LOCUS       DAMKOJ010000001       125342 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000001 DAMKOJ010000000
VERSION     DAMKOJ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 125342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 125342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..125342
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.001"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            109..300
                     /locus_tag="PC592_000001"
     CDS             109..300
                     /locus_tag="PC592_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDF4054034.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMISRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            455..1864
                     /locus_tag="PC592_000002"
     CDS             455..1864
                     /locus_tag="PC592_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF4054035.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKRGEVYKKLGYKDILENLYKM
                     DTTEILGTDNLHFPEGIIKNSQEKASKVFKSDYTYYLVNGSSCGIQSAIMSVCSPKSK
                     IIANRDCHQSVINGCILGDIDIEYVPCEISEDTNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKNMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPSFTQSSMIHIQGNRVNIDKILNMLRMTESSSPSYLLLSSLELAVDIYENKGK
                     GLMEELLNNIRTFKNNIDSNIKMYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTTKDFSSLETALNNVVKEEFKFTKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVYLNFIQVIDLEYI"
     gene            1985..2674
                     /locus_tag="PC592_000003"
     CDS             1985..2674
                     /locus_tag="PC592_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDF4054036.1"
                     /translation="MKGKLIIIESGSDASGKATQTKILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIVIADRY
                     TTSNMVHQASKMDVCDREKYLNWLADYEFNLFKIPQPDCVVFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLQKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKSMER"
     gene            2677..3612
                     /locus_tag="PC592_000004"
     CDS             2677..3612
                     /locus_tag="PC592_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDF4054037.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHRDYKIYIINNAEK
                     MTLEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKSYLI
                     DTGIEEERAQLLATFSRGSIENALNLSQSSEFSVMREDVQQYIQIMLDKNIIEILNIP
                     NNMEKYRGKIITLLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDVKNKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3609..4502
                     /locus_tag="PC592_000005"
     CDS             3609..4502
                     /locus_tag="PC592_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDF4054038.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVFLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4580..5326
                     /locus_tag="PC592_000006"
     CDS             4580..5326
                     /locus_tag="PC592_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDF4054039.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSVKLNGLEERVEIINED
                     IKYIDKVLDVNGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     SRGKFLMIHRPTRLVDIITLGRKYRLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNEDIGEL"
     gene            5327..6160
                     /gene="rsmI"
                     /locus_tag="PC592_000007"
     CDS             5327..6160
                     /gene="rsmI"
                     /locus_tag="PC592_000007"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDF4054040.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGEYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHKFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMFKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDELTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6183..6887
                     /locus_tag="PC592_000008"
     CDS             6183..6887
                     /locus_tag="PC592_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDF4054041.1"
                     /translation="MEIGKIIIESLKREDTHKTFIELDDKHELEKIIPKVSCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNNKDFFPIHLRKHVSNYLNTYIEEGINNLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGINLKLSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSEEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7075..7503)
                     /locus_tag="PC592_000009"
     CDS             complement(7075..7503)
                     /locus_tag="PC592_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF4054042.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7540..8970)
                     /locus_tag="PC592_000010"
     CDS             complement(7540..8970)
                     /locus_tag="PC592_000010"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDF4054043.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLKYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGICKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9102..9686
                     /locus_tag="PC592_000011"
     CDS             9102..9686
                     /locus_tag="PC592_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HDF4054044.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTVIAIITCKFFQRRYR"
     gene            9702..10223
                     /locus_tag="PC592_000012"
     CDS             9702..10223
                     /locus_tag="PC592_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HDF4054045.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10289..10536
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10620..12557
                     /gene="metG"
                     /locus_tag="PC592_000013"
     CDS             10620..12557
                     /gene="metG"
                     /locus_tag="PC592_000013"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDF4054046.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDEAKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKILSCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12587..13357
                     /locus_tag="PC592_000014"
     CDS             12587..13357
                     /locus_tag="PC592_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDF4054047.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIDTSI
                     TAIELAKKYDFIYSAVGVHPHEVSKLDDTAIEILRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKSPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13695..13966
                     /locus_tag="PC592_000015"
                     /pseudo
     CDS             13695..13966
                     /locus_tag="PC592_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
     gene            14128..14964
                     /locus_tag="PC592_000016"
     CDS             14128..14964
                     /locus_tag="PC592_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF4054048.1"
                     /translation="MLTELHCHTNISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEAIVLGEHYGITIIPGIEISAYDYINRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLRYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            14965..15960
                     /locus_tag="PC592_000017"
     CDS             14965..15960
                     /locus_tag="PC592_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4054049.1"
                     /translation="MSFLQVKNVCKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDRDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKKVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDNGINKIAIRPEDIKVEFNRDSKDKDIKEGEILDIE
                     FRGFNYRITVEYCSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            15978..17336
                     /locus_tag="PC592_000018"
     CDS             15978..17336
                     /locus_tag="PC592_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF4054050.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLASLLKNAFM
                     DTSGNFIGILNFSKYIENPSLIASFKNSIFVSIVSSLISLCLAFIYSYAITRTNIKFK
                     NFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKSRDRAFLIVCSLITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAVFGTIFVFFSAYMIEKVDKFPKLRQIAYFLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNIVHFYSVCFITSNSSLKMLDI
                     EV"
     gene            17327..17671
                     /locus_tag="PC592_000019"
                     /pseudo
     CDS             17327..17671
                     /locus_tag="PC592_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
     gene            17863..18393
                     /gene="rnmV"
                     /locus_tag="PC592_000020"
     CDS             17863..18393
                     /gene="rnmV"
                     /locus_tag="PC592_000020"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDF4054051.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQIDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREAFIDALKQI"
     gene            18564..19433
                     /gene="rsmA"
                     /locus_tag="PC592_000021"
     CDS             18564..19433
                     /gene="rsmA"
                     /locus_tag="PC592_000021"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDF4054052.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITGGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLENTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EEIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            19499..20761
                     /locus_tag="PC592_000022"
     CDS             19499..20761
                     /locus_tag="PC592_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054053.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEELEEEDEEVEDNEESNRDEDIEEEEY
                     IIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSSNEEIEEFNNYKEIENYNRVKLQE
                     EYIDIECEEDEEEDEEEVFEVNREDDRFVSSKPTKSKKVQKEQNNIEKIKRVNGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            20912..22027
                     /locus_tag="PC592_000023"
     CDS             20912..22027
                     /locus_tag="PC592_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF4054054.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVV
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEVNGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            22213..23109
                     /locus_tag="PC592_000024"
     CDS             22213..23109
                     /locus_tag="PC592_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF4054055.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDEDLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            23179..23976
                     /locus_tag="PC592_000025"
     CDS             23179..23976
                     /locus_tag="PC592_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054056.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITYGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(24031..25383)
                     /locus_tag="PC592_000026"
     CDS             complement(24031..25383)
                     /locus_tag="PC592_000026"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDF4054057.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYQGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            25602..26480
                     /gene="purR"
                     /locus_tag="PC592_000027"
     CDS             25602..26480
                     /gene="purR"
                     /locus_tag="PC592_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDF4054058.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDIIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            26636..26914
                     /gene="spoVG"
                     /locus_tag="PC592_000028"
     CDS             26636..26914
                     /gene="spoVG"
                     /locus_tag="PC592_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDF4054059.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            27127..28506
                     /gene="glmU"
                     /locus_tag="PC592_000029"
     CDS             27127..28506
                     /gene="glmU"
                     /locus_tag="PC592_000029"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDF4054060.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVIIGNDTIIYPG
                     VMLQGKTKIGSDCIIGMNTSITNSEIGDGTEVKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHNVPDGALAIARERQVIKEGWVEK
                     KNQKDNQSK"
     gene            28600..29550
                     /locus_tag="PC592_000030"
     CDS             28600..29550
                     /locus_tag="PC592_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HDF4054061.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      30389..30474
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            30635..31156
                     /locus_tag="PC592_000031"
     CDS             30635..31156
                     /locus_tag="PC592_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF4054062.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSIKSAALSYYSDTNKIPVTPDGQTGLNVLETYMESLPDKADIGGEYKLIKVG
                     NKLVLQIGKDGEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGEQLKDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            31307..32983
                     /locus_tag="PC592_000032"
     CDS             31307..32983
                     /locus_tag="PC592_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF4054063.1"
                     /translation="MAKKVRIGDKLVEKGYITEDQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            32995..34203
                     /locus_tag="PC592_000033"
     CDS             32995..34203
                     /locus_tag="PC592_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF4054064.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTAFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTPIGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILVSAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISKQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            34218..35930
                     /locus_tag="PC592_000034"
     CDS             34218..35930
                     /locus_tag="PC592_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HDF4054065.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHNKDKFYIKNLNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIIHEFDLILDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQLKAKQMKNILK
                     IAPVVILILAIPYLCLIFSNNLANKELENVNAEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGANNKADNSSSNKTTTDK
                     SSNNETKSNTKSDSNGDKTNNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSTYTFSMTLYLKEGV
                     LTNE"
     gene            35923..36831
                     /gene="pilO"
                     /locus_tag="PC592_000035"
     CDS             35923..36831
                     /gene="pilO"
                     /locus_tag="PC592_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HDF4054066.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGVLIKVIILLSILSYGYFGLYPQ
                     YQKYIVTKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVREYEHFYGVSTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTSYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            36858..37424
                     /locus_tag="PC592_000036"
     CDS             36858..37424
                     /locus_tag="PC592_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF4054067.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGSNYEYNIETPDNIVKYEVSIETKKN
                     TEVYSVTRIEKNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTDKSIYTVSIF
                     YNESVQEGHKNSNLNNKTYTFDVMSRIG"
     gene            37460..37987
                     /locus_tag="PC592_000037"
     CDS             37460..37987
                     /locus_tag="PC592_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF4054068.1"
                     /translation="MSKKNSKRGFSLIEVLVAMAIMGIILFAFFNIINTNNKANIKND
                     TDINSLNYVQSEIENLREKIKSGEFDFDSLDKMEDGTVVYEKLIDKSKKIVYDKVLSE
                     GNVSLYDTPYEKITTIKDEDGNLIDKENITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            38008..39546
                     /locus_tag="PC592_000038"
     CDS             38008..39546
                     /locus_tag="PC592_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054069.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLMFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQQKSISRSKLRNISDE
                     DFNNQNEENLEVERLGYMNNINFYLNKASSDLEKASIELKKLYDLDMLDYRDIEYVDE
                     NIISHRNSILDICKNYTSGDISKINEYILDEDINSTTLVEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSYTYKALDKISLAMQNMIEYRHTFHIDEQKVEVSNGIPNSQQYYELIQ
                     NPIINSKEYSWNSKWDTLENLLETLPNQTQGFNSLRVHLRNNVRKFEELSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEVDKTEDITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDSKKNIIGLGVEENSNSKYKVEAIINFNLNIDTNIVGNYDIKDKILINHDISSY
                     KKVN"
     gene            39646..40728
                     /locus_tag="PC592_000039"
     CDS             39646..40728
                     /locus_tag="PC592_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDF4054070.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTP
                     EVTMQMAKDIAGESMFKVIKEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPENIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKSGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            40709..41491
                     /locus_tag="PC592_000040"
     CDS             40709..41491
                     /locus_tag="PC592_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF4054071.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLISGRKCRYCYEKISSRYAIVELITGILFLIVFMLYGISTSTV
                     YYLVLVSLLIIITFIDIDHFIIPDEILIFGAIFAIIFNLLFKEIPVKDSIIGFFICGG
                     SVWLIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNSLLTALLSVYVGAVYGICVII
                     ISKTKGKEYNSIIPYGPFISVGALITILCGKQLLEFYFSMIT"
     gene            41593..42243
                     /locus_tag="PC592_000041"
     CDS             41593..42243
                     /locus_tag="PC592_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF4054072.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFCNI
                     VQFDYINHIFGLVIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDIDIKKQIPFTPFISLATILIMFTEYNIFNFYYSLLYKFI"
     gene            42257..42817
                     /locus_tag="PC592_000042"
     CDS             42257..42817
                     /locus_tag="PC592_000042"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDF4054073.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEVGQDLADFVLSRFRKEESDNINE
                     ALEKAAYAIDSIIRENIDMSMNKYNG"
     gene            42834..46220
                     /gene="mfd"
                     /locus_tag="PC592_000043"
     CDS             42834..46220
                     /gene="mfd"
                     /locus_tag="PC592_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDF4054074.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYIEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDNLDLERLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTTNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            46251..47246
                     /locus_tag="PC592_000044"
     CDS             46251..47246
                     /locus_tag="PC592_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF4054075.1"
                     /translation="MKKVITLVIAMILVVSVTACNSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFTKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSAKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDASASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            47369..47908
                     /gene="spoVT"
                     /locus_tag="PC592_000045"
     CDS             47369..47908
                     /gene="spoVT"
                     /locus_tag="PC592_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HDF4054076.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            48028..49641
                     /locus_tag="PC592_000046"
     CDS             48028..49641
                     /locus_tag="PC592_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF4054077.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNIMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLMFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICIGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            49748..51196
                     /gene="mazG"
                     /locus_tag="PC592_000047"
     CDS             49748..51196
                     /gene="mazG"
                     /locus_tag="PC592_000047"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDF4054078.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLKNSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEIVPSMSFVDAMFNYLAIDPSEGFKLVDAFEIDNSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEYYDYNQEVCIVNGAGVKDLENKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     EFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            51285..51563
                     /locus_tag="PC592_000048"
     CDS             51285..51563
                     /locus_tag="PC592_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDF4054079.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            51635..51877
                     /locus_tag="PC592_000049"
     CDS             51635..51877
                     /locus_tag="PC592_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDF4054080.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            51939..52193
                     /locus_tag="PC592_000050"
     CDS             51939..52193
                     /locus_tag="PC592_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HDF4054081.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            52194..52727
                     /locus_tag="PC592_000051"
     CDS             52194..52727
                     /locus_tag="PC592_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054082.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKSKN
                     KKKSKPKKKKNKTKKRV"
     gene            52733..53017
                     /locus_tag="PC592_000052"
     CDS             52733..53017
                     /locus_tag="PC592_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDF4054083.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINALKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            53130..54050
                     /locus_tag="PC592_000053"
     CDS             53130..54050
                     /locus_tag="PC592_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HDF4054084.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSNKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQDDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEELEAMSSFIYDEIDKTLNHIKYRGLKTLIGIGGTITSLSAMNQ
                     ELEVYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            54140..56512
                     /gene="spoIIE"
                     /locus_tag="PC592_000054"
     CDS             54140..56512
                     /gene="spoIIE"
                     /locus_tag="PC592_000054"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HDF4054085.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISIGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAIYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            56863..58755
                     /gene="pepF"
                     /locus_tag="PC592_000055"
     CDS             56863..58755
                     /gene="pepF"
                     /locus_tag="PC592_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF4054086.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNGDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDEQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMSDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNGNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            58869..59834
                     /gene="galU"
                     /locus_tag="PC592_000056"
     CDS             58869..59834
                     /gene="galU"
                     /locus_tag="PC592_000056"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF4054087.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEIVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEIRELEIQK"
     gene            60334..61938
                     /gene="rho"
                     /locus_tag="PC592_000057"
     CDS             60334..61938
                     /gene="rho"
                     /locus_tag="PC592_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDF4054088.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKINEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQENRNQRNDYNKTTSVNDCNKPSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            62091..62291
                     /gene="rpmE"
                     /locus_tag="PC592_000058"
     CDS             62091..62291
                     /gene="rpmE"
                     /locus_tag="PC592_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDF4054089.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            62436..63329
                     /locus_tag="PC592_000059"
     CDS             62436..63329
                     /locus_tag="PC592_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HDF4054090.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            63347..64195
                     /gene="prmC"
                     /locus_tag="PC592_000060"
     CDS             63347..64195
                     /gene="prmC"
                     /locus_tag="PC592_000060"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDF4054091.1"
                     /translation="MTIKDIIIKYSDILKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTEFIGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISEIALEIAKKNAITNEV
                     DEKIKYINSDLFTAISNSNIKFDIIVSNPPYIKKQDIETLHTQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKFGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            64239..65303
                     /gene="prfA"
                     /locus_tag="PC592_000061"
     CDS             64239..65303
                     /gene="prfA"
                     /locus_tag="PC592_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDF4054092.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            65432..66112
                     /locus_tag="PC592_000062"
     CDS             65432..66112
                     /locus_tag="PC592_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDF4054093.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGISGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDMSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            66141..67181
                     /locus_tag="PC592_000063"
     CDS             66141..67181
                     /locus_tag="PC592_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDF4054094.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNIIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVAIKINDMIKSNREKGLKTGVMC
                     TSKNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKSVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            67198..67647
                     /locus_tag="PC592_000064"
     CDS             67198..67647
                     /locus_tag="PC592_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDF4054095.1"
                     /translation="MNILIVCTGNTCRSPMAEAILKKAIKESGRSVEEYSISSAGIST
                     ANGMSASENSIKALKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILLQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDSYRSTMREIVYSVNEIVKKI"
     gene            67664..68116
                     /gene="rpiB"
                     /locus_tag="PC592_000065"
     CDS             67664..68116
                     /gene="rpiB"
                     /locus_tag="PC592_000065"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF4054096.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLEGKGIECVDYGTNNATDSVDYP
                     VYGEVVANSVINKDVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNNA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            68152..68781
                     /gene="upp"
                     /locus_tag="PC592_000066"
     CDS             68152..68781
                     /gene="upp"
                     /locus_tag="PC592_000066"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDF4054097.1"
                     /translation="MSKVIETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            69081..69896
                     /locus_tag="PC592_000067"
     CDS             69081..69896
                     /locus_tag="PC592_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDF4054098.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEDVECIFCNTEKEIEEALSQRKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRTITNGRAEKNTGVPG
                     AIKGFSKERVMHSQHDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGARVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            70122..70559
                     /locus_tag="PC592_000068"
     CDS             70122..70559
                     /locus_tag="PC592_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF4054099.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            70744..70971
                     /locus_tag="PC592_000069"
     CDS             70744..70971
                     /locus_tag="PC592_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HDF4054100.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            70976..71362
                     /locus_tag="PC592_000070"
     CDS             70976..71362
                     /locus_tag="PC592_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDF4054101.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAIRLFIMAVVLFASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            71365..72069
                     /gene="atpB"
                     /locus_tag="PC592_000071"
     CDS             71365..72069
                     /gene="atpB"
                     /locus_tag="PC592_000071"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDF4054102.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGQILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            72138..72398
                     /gene="atpE"
                     /locus_tag="PC592_000072"
     CDS             72138..72398
                     /gene="atpE"
                     /locus_tag="PC592_000072"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDF4054103.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            72521..73018
                     /gene="atpF"
                     /locus_tag="PC592_000073"
     CDS             72521..73018
                     /gene="atpF"
                     /locus_tag="PC592_000073"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDF4054104.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKNDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQEKQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            73015..73560
                     /locus_tag="PC592_000074"
     CDS             73015..73560
                     /locus_tag="PC592_000074"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDF4054105.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIAGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            73577..75079
                     /locus_tag="PC592_000075"
     CDS             73577..75079
                     /locus_tag="PC592_000075"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDF4054106.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            75107..75985
                     /gene="atpG"
                     /locus_tag="PC592_000076"
     CDS             75107..75985
                     /gene="atpG"
                     /locus_tag="PC592_000076"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HDF4054107.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIVKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMEVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            75998..77392
                     /gene="atpD"
                     /locus_tag="PC592_000077"
     CDS             75998..77392
                     /gene="atpD"
                     /locus_tag="PC592_000077"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDF4054108.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVKKAKGSM"
     gene            77395..77655
                     /gene="atpC"
                     /locus_tag="PC592_000078"
     CDS             77395..77655
                     /gene="atpC"
                     /locus_tag="PC592_000078"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HDF4054109.1"
                     /translation="MASEFSLKVVTPNNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFVNVTQDKTVILTESAEWI"
     gene            78108..78488
                     /locus_tag="PC592_000079"
     CDS             78108..78488
                     /locus_tag="PC592_000079"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDF4054110.1"
                     /translation="MNIFDIGVDIIEIDRIRKAIEKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            78503..78964
                     /locus_tag="PC592_000080"
     CDS             78503..78964
                     /locus_tag="PC592_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF4054111.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            78985..79575
                     /locus_tag="PC592_000081"
     CDS             78985..79575
                     /locus_tag="PC592_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054112.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDIVELPNTGKNNQYLFIGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            79590..80747
                     /gene="alr"
                     /locus_tag="PC592_000082"
     CDS             79590..80747
                     /gene="alr"
                     /locus_tag="PC592_000082"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF4054113.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKVCGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIVTIPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            80780..81067
                     /locus_tag="PC592_000083"
     CDS             80780..81067
                     /locus_tag="PC592_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDF4054114.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            81036..81419
                     /locus_tag="PC592_000084"
     CDS             81036..81419
                     /locus_tag="PC592_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF4054115.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            81590..82417
                     /locus_tag="PC592_000085"
     CDS             81590..82417
                     /locus_tag="PC592_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF4054116.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            82410..83351
                     /locus_tag="PC592_000086"
     CDS             82410..83351
                     /locus_tag="PC592_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF4054117.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKAF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNVIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIVKTVKEAIIAKRM"
     gene            83773..84867
                     /locus_tag="PC592_000087"
     CDS             83773..84867
                     /locus_tag="PC592_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054118.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDRLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPIIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDNHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            85093..85509
                     /locus_tag="PC592_000088"
     CDS             85093..85509
                     /locus_tag="PC592_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054119.1"
                     /translation="MDVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(85691..86260)
                     /locus_tag="PC592_000089"
     CDS             complement(85691..86260)
                     /locus_tag="PC592_000089"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDF4054120.1"
                     /translation="MKKEFRKKVIESRKNKNANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLDFNNEVQTDNLIKKLLSLKKIVSSPITIKENRTLIPTQITDLKDGLRIGAYGIR
                     EPNEKSPKIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFNSIPKETHDAQLDYIVTETRIITPNN"
     gene            86414..87571
                     /locus_tag="PC592_000090"
     CDS             86414..87571
                     /locus_tag="PC592_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDF4054121.1"
                     /translation="MYLVISKKKAIFLGVILIIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGASKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIVEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTGAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            complement(87753..88907)
                     /gene="nagA"
                     /locus_tag="PC592_000091"
     CDS             complement(87753..88907)
                     /gene="nagA"
                     /locus_tag="PC592_000091"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF4054122.1"
                     /translation="MKSFIYADKFFMKHGTKEKGYLSIINGKFGEFQQERPSTTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNKVEGAKIQGIYLEGPFFTEKYKGAQNEKYFQDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTKYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAIKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLSSGSLAGSVLTMDRAVRNMVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDKGFNIHETYINGICKYKVNK"
     gene            complement(88990..89715)
                     /locus_tag="PC592_000092"
     CDS             complement(88990..89715)
                     /locus_tag="PC592_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4054123.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPSTK
                     VLSFEVVESTKYFSEKLGITPGEKIIKIMRLRLANDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEVIKVADEEFSAGIISDKEATLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            89985..90914
                     /gene="pfkB"
                     /locus_tag="PC592_000093"
     CDS             89985..90914
                     /gene="pfkB"
                     /locus_tag="PC592_000093"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF4054124.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAIGFLGGFNGEFIKNELKKLEIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESRDEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNKDSVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLREIDKYQDLVEVKKLS"
     gene            complement(91043..91960)
                     /locus_tag="PC592_000094"
     CDS             complement(91043..91960)
                     /locus_tag="PC592_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF4054125.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVNQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKHFSINTSMHRDSG
                     TKLEQVEILSKGRIQRIKNLNVLEIEEGGNLILKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECVKAQRLLEKIINSVK"
     gene            92432..93601
                     /locus_tag="PC592_000095"
     CDS             92432..93601
                     /locus_tag="PC592_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF4054126.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEEL
                     RRFIDKISNNHGQFRVIFTGAGTSAYVGNSILPYLKNNNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDVPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPQGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKIATVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            93650..94501
                     /gene="gatY"
                     /locus_tag="PC592_000096"
     CDS             93650..94501
                     /gene="gatY"
                     /locus_tag="PC592_000096"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF4054127.1"
                     /translation="MALVTTTSMLKKAQDGGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLNEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNKV"
     gene            94830..96731
                     /locus_tag="PC592_000097"
     CDS             94830..96731
                     /locus_tag="PC592_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF4054128.1"
                     /translation="MRERIILEALKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFKGNRNITKYRNKFIDNIKLDNIRSTIKNVLNEHYLEANLTELEEILAQIIILYIRV
                     STRVVRSPSDLELYTEDLIIDELLDKIFGDKKYSLTYDEKYYLKQLIKLRTKDKKATI
                     KNIDKNKLQDIMCEFFRDIDKKYNSNFLEDKEFLNLFYLHIACLIERIKKNHKITNPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIKNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESFRFVDHIGNVSSPKQYILGLFDKNHFRCVKEKTKYK
                     DILDSMSQCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDINYENRVPKIIFMISLIKGNLELHKQISKYLSKIMTDKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            96734..97777
                     /gene="ypdE"
                     /locus_tag="PC592_000098"
     CDS             96734..97777
                     /gene="ypdE"
                     /locus_tag="PC592_000098"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF4054129.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELRAYSDKVICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLMTIGGVKPLAQFVQKVRITT
                     KEGKKIHAIINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTNFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELKKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMKIASENNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEKYRHIRNFI"
     gene            97792..98097
                     /locus_tag="PC592_000099"
     CDS             97792..98097
                     /locus_tag="PC592_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF4054130.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            98194..98529
                     /locus_tag="PC592_000100"
     CDS             98194..98529
                     /locus_tag="PC592_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054131.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            98561..99883
                     /locus_tag="PC592_000101"
     CDS             98561..99883
                     /locus_tag="PC592_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4054132.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGEDNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKIFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPIFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLTVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            99893..100963
                     /locus_tag="PC592_000102"
     CDS             99893..100963
                     /locus_tag="PC592_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF4054133.1"
                     /translation="MNNTIERLVSLIDKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQVLDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAISI
                     QEYLSLKNAGFKINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVAREIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            100968..102155
                     /locus_tag="PC592_000103"
     CDS             100968..102155
                     /locus_tag="PC592_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF4054134.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKEAILKRASIGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVLNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDLKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETHIPKANVMKSDSSFLAWIDVR
                     GVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(102352..103224)
                     /locus_tag="PC592_000104"
     CDS             complement(102352..103224)
                     /locus_tag="PC592_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDF4054135.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWNGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVSYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPSCEQNDFSKHYL
                     EFKSRNDVEKINLSGSFTDDIISIGKLKNLQLNPELFKNDALIYTNIDEVSICNNNGS
                     KYVTISMKDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADNINSNKIYKDKKFINKLS
                     KGKVFTASYSININ"
     gene            complement(103618..103809)
                     /locus_tag="PC592_000105"
     CDS             complement(103618..103809)
                     /locus_tag="PC592_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054136.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            104029..105075
                     /gene="cobT"
                     /locus_tag="PC592_000106"
     CDS             104029..105075
                     /gene="cobT"
                     /locus_tag="PC592_000106"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDF4054137.1"
                     /translation="MSLLESISKNIYSLDSSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFNIIEASNYT
                     YKNMATFDEIDMGR"
     gene            105107..105667
                     /gene="cobU"
                     /locus_tag="PC592_000107"
     CDS             105107..105667
                     /gene="cobU"
                     /locus_tag="PC592_000107"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDF4054138.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCLDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFKHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIAG
                     RINQYIASKSNEVYFVVSGIPMKIKE"
     gene            105677..106450
                     /gene="cobS"
                     /locus_tag="PC592_000108"
     CDS             105677..106450
                     /gene="cobS"
                     /locus_tag="PC592_000108"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDF4054139.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLVGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRNKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKIGFIYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSTIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSEVVYLIYIYLLNFMFF"
     gene            106470..107084
                     /locus_tag="PC592_000109"
     CDS             106470..107084
                     /locus_tag="PC592_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF4054140.1"
                     /translation="MIRLILIRHALTNDNKKGKLSGHINSCISEEGKLQINKITRYLS
                     NENIDKIYTTPSTRTKDTIEKISKLKLLEIEEKETLREISFGDFEGITFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLGSKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLDVDSGFTVIDKMNFTDFI"
     regulatory      107151..107330
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            107460..108959
                     /locus_tag="PC592_000110"
     CDS             107460..108959
                     /locus_tag="PC592_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HDF4054141.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKIKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            108998..110374
                     /locus_tag="PC592_000111"
     CDS             108998..110374
                     /locus_tag="PC592_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HDF4054142.1"
                     /translation="MKKILIAGTSSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYRELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDESVPNADYIYIGGGFPEIFGKELEANESMRVSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLNKGNE"
     gene            110375..111346
                     /locus_tag="PC592_000112"
     CDS             110375..111346
                     /locus_tag="PC592_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF4054143.1"
                     /translation="MNILSIYIGYVTDLIIGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLSYDHRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            111378..112442
                     /locus_tag="PC592_000113"
     CDS             111378..112442
                     /locus_tag="PC592_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF4054144.1"
                     /translation="MKDLGHGANVDEMARLYGKDPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRKNISKYIDINPDFIIPGNGATEVIYLLMKSIKKRLAIINP
                     TFSEYRRSAKLNNLDIIDLELESNFKLNIDIIKENIERFDSLFICNPNNPSGNVQDLK
                     ELVNLLGKHNKVLIIDETFMEFVEDESKHSLVKYIESNKNIFIIKAVTKFFGMPGLRL
                     GYGLTSNAEIMNKIYEYKEPWTINSFADILSNFIFEDREYIKDSKEYYIKERSYMLQE
                     LRNIRNIKVYDTDANFILIRTYKKTAKELKKDLFKQGNILVRDASNFIGLDDSFIRVA
                     IKSHKDNKILIENMKNLLGD"
     gene            112444..113331
                     /locus_tag="PC592_000114"
     CDS             112444..113331
                     /locus_tag="PC592_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF4054145.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKDTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVIILEPN
                     KVLDTMKIRLRQDYSRLKTENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     DKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKNMIDALCESNINSVYSK
                     IYTLNIINGGIKGEIEWNT"
     gene            113319..113951
                     /locus_tag="PC592_000115"
     CDS             113319..113951
                     /locus_tag="PC592_000115"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HDF4054146.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVASIIDALRNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKERGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAEESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            113960..115186
                     /locus_tag="PC592_000116"
     CDS             113960..115186
                     /locus_tag="PC592_000116"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HDF4054147.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLSLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVSKNDKNKEY
                     LTLKDIDGLSNNSESQSELYKFIRVYGGIGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRNLIGDNFESILGNNKVLKITIFAPQGEAVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRTSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKISAGIFNTHSKVADARSEILVANLALMGATYEFLN
                     KINQCLTTEEAVELINNSEYRQVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            115183..115791
                     /locus_tag="PC592_000117"
     CDS             115183..115791
                     /locus_tag="PC592_000117"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HDF4054148.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYISKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREVIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            115781..116356
                     /locus_tag="PC592_000118"
     CDS             115781..116356
                     /locus_tag="PC592_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HDF4054149.1"
                     /translation="MRNSEFVTGKVPITKEEVRAISISKLNLVNAKNFIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNIRKFNLKNIEVIKGYAPINLGLNTKVESI
                     FLGGTGNNLEEIIEWSKKNLVVGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            116349..117101
                     /locus_tag="PC592_000119"
     CDS             116349..117101
                     /locus_tag="PC592_000119"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HDF4054150.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSDADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSRLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            117085..118206
                     /gene="cbiG"
                     /locus_tag="PC592_000120"
     CDS             117085..118206
                     /gene="cbiG"
                     /locus_tag="PC592_000120"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HDF4054151.1"
                     /translation="MNIEGNIAIICITENGKKLAVKINSLVNNCVIYQIKNKKSNLNV
                     EETCVHTVQKKLSDFVGEIFNKFDYIVFIMATGIVVRSIAPYIISKFSDPAVLVMDEK
                     GENVISLLSGHIGGANSLTQYISSLIDANPVITTATDVNQKASLDMIAKKLNAYIDTF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLLESKDELRDSFSNIYIEKLVVVSN
                     KINCIEDIENLNLDNKFELYYSTEKIIKVIPKDIVIGIGCRRNTDSELMYNSLKEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKTLKVPFKTFSIDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            118203..118928
                     /gene="cobJ"
                     /locus_tag="PC592_000121"
     CDS             118203..118928
                     /gene="cobJ"
                     /locus_tag="PC592_000121"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HDF4054152.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVAEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKDGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYIDGELMITPRGYTV"
     gene            118925..119677
                     /gene="cobK"
                     /locus_tag="PC592_000122"
     CDS             118925..119677
                     /gene="cobK"
                     /locus_tag="PC592_000122"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HDF4054153.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAN
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKNAITCAKLSNIDYIRFERKSL
                     IDEIDYDNKFIVNTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIIAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            119696..121174
                     /locus_tag="PC592_000123"
     CDS             119696..121174
                     /locus_tag="PC592_000123"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HDF4054154.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSYDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESDEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGVNAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEEDGFNVRVHLKGLGENSYIQDKFVRHALKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            121204..122109
                     /gene="hemC"
                     /locus_tag="PC592_000124"
     CDS             121204..122109
                     /gene="hemC"
                     /locus_tag="PC592_000124"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDF4054155.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLYGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPRGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSKIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            122099..123598
                     /gene="cobA"
                     /locus_tag="PC592_000125"
     CDS             122099..123598
                     /gene="cobA"
                     /locus_tag="PC592_000125"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDF4054156.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSNYLR
                     EAKPDCEFIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLNKISENLMKEGKDKNTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVELREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNIKLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELMPILNNSDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEDKKDEILDILNSNNIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTDTINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            123615..124586
                     /gene="hemB"
                     /locus_tag="PC592_000126"
     CDS             123615..124586
                     /gene="hemB"
                     /locus_tag="PC592_000126"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDF4054157.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEEEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINADMNVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGANMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKNKF"
     gene            124729..125307
                     /locus_tag="PC592_000127"
     CDS             124729..125307
                     /locus_tag="PC592_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HDF4054158.1"
                     /translation="MLYPINLKLDDLDVVIIGGGEVAYRKCKNFLNFNKRVTIVSKQL
                     LNKFYDLKEYINIIEDDYKEVYIEKASIVIAATNNKVLNMEIGLYCRAEHKLVNVVDN
                     VEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEEIYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLITLDLEELKKFDI"
BASE COUNT        50155 a        13398 c        22799 g        38990 t
ORIGIN      
        1 ttttttgtca aaaaaaacaa aaaatacgta tttctttttt catttcggga aaactaaaca
       61 caggaattat ggactttata aaaatttaat tctcgaggag tgatataagt gaaaaaagtt
      121 gctttaattt tagctataat aggtgcgctt aactggggtg caattggtat tctaggcaca
      181 gacttaatag gtagtatctt tggtggaaca tatgaaatga taagtagaat aatatacttc
      241 attgtaggtt tagctggatt atacttaata ccaagtttaa tgtctgatga tagagaataa
      301 tttatgcttt tatgttaaat acctcattct aaatatttag aatgaggtat ttaattttat
      361 aaaaatatta atttgtttct tttttaatgg taaaatagat aagaattgaa gttttaaaaa
      421 gaagtattat ctaaaaaagg agtactatta atatatgttt attattaatg aattaaataa
      481 gattgtaaat gaagaagtaa tatcttttca tatgcctggt cataaaagag gagaggttta
      541 taaaaagttg ggatataaag atatactaga gaatttgtat aaaatggata caacagagat
      601 attaggaaca gataatttac attttccaga agggattata aaaaattcac aagaaaaagc
      661 atcaaaggta tttaaaagtg attatactta ctatctagta aatggtagta gctgtggaat
      721 acaatctgca ataatgtcag tatgcagtcc aaaaagtaaa ataatagcaa atagagattg
      781 tcaccagtct gttataaatg gatgtatttt gggagatata gatatagagt atgtaccttg
      841 tgagataagt gaagatacaa atgttttaaa aggtatatct ataagtaatg tgattgatat
      901 aatagataaa aacttggatg caaaagcggt actgcttact tatcctacat attatgggat
      961 gacatatgat ttagaataca tatgtaatta tgcacatagc aaaaatatgg tagtgatagt
     1021 agatgaagca catggtgcac atttagggct tagtgaaaga cttcctaaaa cggctcttga
     1081 gcaaggtgca gatatagttg tacagagtac acataaaact cttccatcat ttacacaatc
     1141 gtcaatgata catatacagg gaaaccgagt taatatagat aaaatattaa acatgttaag
     1201 aatgacagaa tcttcaagcc cttcatactt attattatct tctctggaat tagcagtaga
     1261 tatatatgaa aataaaggaa aaggattaat ggaagaactt ttaaataata ttagaacttt
     1321 caaaaataat attgattcaa atattaagat gtatgacaca aatgataaaa caaaaatatt
     1381 tatatcatct aaaaatatgg gtttaacagg ttatgaatta gaaaatattt taagaaacaa
     1441 atataacata caagtggaat tatctaatta ttatggagtt cttttaatat gcacaatagg
     1501 aaatactact aaagatttct ctagtttaga aacagcatta aacaatgttg taaaggaaga
     1561 atttaaattt acaaagctag aaaataaaaa ataccctgtt gttattccga agaaaatatt
     1621 aacacctaga gaagcatttt ataaaactaa aaaaagtgtt aaaatatatg acagcatagg
     1681 taaaatttgt ggtgaatgta tagtgccata cccacctgga ataagtgtaa tatctcctgg
     1741 tgaagtaata agtaaagaaa taatagacta cctaatgttt tgccattcta aaggtatgat
     1801 tgtgagtggt ttgaaagatg tatatttaaa ttttatacaa gtaatagatt tagaatacat
     1861 ttaaaactta tgatataaaa gtagatagtt taaaatttcg aagagaaata aatagactgt
     1921 ttatatagag ctatataata agagtattaa aaaagtaaaa agtatttgta tggaggatat
     1981 gaaaatgaaa ggtaagctaa taattataga gagtggttca gatgcaagtg gaaaggctac
     2041 tcagacaaaa atattatatg aaagattaaa aaaagaaggc tatatgatta aaaaggtaga
     2101 atatccaaat tatgaatctc catcatctgc attggtgaaa atgtatttaa aaggagactt
     2161 tggtaaaaat gcatcagatg tagacccata tatagcatca acttttttta cagctgatag
     2221 gtatgcatca tttaaaaccg attgggagga gttttacaat gaaggtggaa tagttatcgc
     2281 agatagatat acaacctcta atatggtaca tcaggcctct aaaatggatg tttgtgatag
     2341 agaaaagtat ttaaattggt tggctgatta tgaatttaat ttatttaaga taccacaacc
     2401 tgattgtgtt gtatttttag acgtgcctat tgaatttagt aaaaagctta tggagaatag
     2461 aaaaaataaa attacagggg aagaaaaaaa ggatattcat gaaagtgaca tagagtattt
     2521 acagaaatct tacaacaatg ctttatatat agcagataaa tatgattgga aaaaaataaa
     2581 ttgtgtttta gataacaaat taagaagtat tgaaagtata cataatgaaa tttataaaat
     2641 agttcttgat tcaataaaat ctatggagag ataaatatgt attttgaaaa tattataggg
     2701 caagattttg caaagaaata tttaacaaat tctataaaga aaaataaact taataatgcg
     2761 tatatgtttg agggaatgga tggaatagga aaaaagaaat ttgctgatga gttatcaaaa
     2821 ctattacttg attatgaaaa tctcgaaaat agtccagact atgtactcat aaagccagat
     2881 ggaaatagca taaaaatagc tcaaatcaga aatttacaat cagatatagt aataagacct
     2941 catagagact ataaaatata tataattaat aatgctgaaa aaatgactct ggaagctcaa
     3001 aatgcacttt taaagacgct ggaggaacct ccaaactatg ctataataat cttagtcaca
     3061 aacaacaagg aatctttatt agaaactata aaatctagat gtgatataat aaagttctca
     3121 cctataccaa ttgaggactt aaaaagttat ttgatagata caggtataga agaagaaaga
     3181 gctcaattat tggctacttt ttcgagagga agtattgaga atgctctaaa tctatctcag
     3241 tcttctgagt tttcagttat gagagaagat gtacaacagt atattcagat aatgttagat
     3301 aaaaacataa tagagattct aaatatacca aataatatgg aaaaatatag aggtaagatt
     3361 atcactttat tagatatgat gataaactat tttcgagata ttattctatt aaaagaaaat
     3421 gtaaacaaga acatgttaat aaatgtagat aagctggtct tcattcaaaa tatgagtgga
     3481 aaaattagtt attctcaatt gtctaagatt attgatataa tagaagatgt aaagaataaa
     3541 ataaaaagca attgcaattt caatataagc atacaagtta tgtctttaaa tatatacgag
     3601 gtgattaaat gataaagata gtaggtataa ggtttaaaag tgctgggaaa atatattatt
     3661 ttgaccctgt tgattttaat atagagcaag atatggatgt agttgtagaa actgcaagag
     3721 gcttggagta tgggaaagta gtcgttggtc caaaagatat ggatgaaagc gaattagttt
     3781 ctcctttgaa gccaattata agaatagcta cagaagaaga taaaaaagta tttctagaaa
     3841 ataaggaaaa ggcaaaagaa acttttgagt tatgtcaaca aaaaataaaa gaacatgagt
     3901 taacaatgtt tttaatagat tgtgagtata catttgatag aaataagttg attttttact
     3961 ttacagcaga aggaagaata gattttagag aattggtaaa agatttagct gctatattta
     4021 aaactagaat agaacttaga caaataggtg tcagagatga agctaaatct ataggaggtc
     4081 taggtccttg tggtagaaaa ctttgttgtt catcttggtt aggtgatttt caaccagttt
     4141 caataaaaat ggcaaaagac caaagtttat ctctaaatcc aacaaaaata tctggaatat
     4201 gtgggagatt attctgttgc ttaaagtatg agcatgatgt atatagtgag gcaatagaaa
     4261 aaatgcctgt tgtaggtgca ttggtgcaat cagatgatgg gaaaggaaaa gttgtagaag
     4321 taaatccttt attagaacaa attaaagtag aatttcaaga taagacagtg aagatatata
     4381 caagagaaga tataaaaata cttagagagc ctaaaaaatg tgatggctgt ggtggtaaat
     4441 gtaaggataa tgatggatta gatgaggcca cactaagaga gctaaagaaa ttagaagatt
     4501 aaattcaagg tagggctttt cctacctttt ttaaagcaat taatgcttaa agttattaat
     4561 atttgaggag aatttatata tgcaattaaa agattcagaa agaatagatg atttacaatt
     4621 aaaaggcctt aaaattatac aagatactaa tggtttttgt tttggtatag atgcagtttt
     4681 attagccaat tttactaaaa taaaaaaaga cgctaaagta gtagatttgg gtactggaac
     4741 tggcataata cctattttga tagctggaaa aagtgaagct aaaaaaatta ttggtgtgga
     4801 aatacaagaa gatgtatatg aaatggcaac tcgttctgta aaattaaatg gattagaaga
     4861 aagagttgag attataaatg aagatataaa atacatagac aaagtcttag acgtaaatgg
     4921 ttaccatgta gtcacatcaa atcctccata tatgcatatt gatggaataa aaaatccaaa
     4981 tgataaaaaa gcaatatcaa gacatgaagt aaggtgtaat ttggaagatg taattagagc
     5041 tgcatctaga ttggttatgt ctagaggaaa atttctcatg atacatagac caacaagatt
     5101 ggttgatata ataactttag ggagaaaata tagattagag ccaaaggtta ttcaatttgt
     5161 gcatccaaga cctcaaaaag cacctaattt agtcttggtt caatttgtaa aagatggaag
     5221 accagagctt aaaatattgg acccattgta tgtttatgga gaagatggga attatacaaa
     5281 agaattaaaa gcaatatata ataatgaaga tataggagag ttgtagatga gtggaaaatt
     5341 gtacatatgt ccaacaccaa taggaaactt agaagatata acatatagaa ctttaagaat
     5401 attaaaagag gtagacttga ttgcggctga agatacaaga catagtataa aacttttaaa
     5461 tcattttgaa atctcaaagc cattaactag ttatcatgaa cataataagg attcaaaggg
     5521 agaatatttg ataaataaac taattgatgg tgaaaatata gctctgataa gtgatgcagg
     5581 tatgccaggt atatctgacc caggagaaga gataataaaa caagctatac aaaataacat
     5641 agagatagaa gtattaccag gtgcaacagc atttgtaaca gctttagttg gttctggtat
     5701 ggacacacat aaatttgttt ttgagggctt tttagataga gataaaaaag ttaggaaagc
     5761 acaattggaa gaattaaagg aagaaagtag aactataatt ttttatgaat caccgcatag
     5821 attgaaggat acactaaaag atatgtttaa aattcttggt aataggaata tttctataaa
     5881 tagagagctt acaaaaaaat atcaagagat aataagagaa aatatagaaa ctacaataaa
     5941 gatatttgaa gaaaaagaag taagaggaga gtttgtatta atagtagagg gttttcatgg
     6001 tgaaaagtca aagaaagaaa attatgatga gcttactgat agggaatatg ttttaaaact
     6061 aattgaaagt ggtatgaaca aaaaagatgc aataaaaata gtttgtaaag atagaaagtt
     6121 aaagaaagat gtggtttata aacaagttct agatttataa aacctgaatc tgaggtgatt
     6181 ttatggaaat aggaaaaatt ataatagaga gtttaaagag agaagataca cataaaacat
     6241 ttatagaatt agatgataag catgaattag aaaaaataat tcctaaagta agctgtatga
     6301 aatctgtagg tgaatgtaaa tatcatgtag taaattgttt tgaacactct ataaatgcat
     6361 taaaagaatt agaaatagta ttaaataata aggatttttt tccaatacat ctaagaaaac
     6421 atgtttcaaa ctatttaaac acatatattg aggaaggaat aaataattta catgtattaa
     6481 agttaggaac atttttacat gatataggta aacctgatag catgacttta gatgaaacag
     6541 gaagagttca tttcacaaat catgaaaaaa taggtgctca aataattgac aatatgggga
     6601 taaatctgaa gttatcaaca gaaacatata gacttataag taaatatgta aggtatcata
     6661 tgatactttt gtctttgtat aagaaaaatg atttaagtag gaaagaatta attaatgtat
     6721 ttaacttagt agatgaggac actataggag taataatgct tggatatgca gatatagtat
     6781 ctacagtaaa attattaggt aagagtgaag aagtcagtgt attaaagaca tatatggaat
     6841 atattttaac aaattacttg tataaaagta attatacaca tgtataaatt tagtcaatat
     6901 aattgagttt taaatggtta attgaagttt gaaatatata gatttcaaaa acataaaaga
     6961 agttgtcttt gttgtaaaat tatgaaagac aacttttttt atatcaaaaa ttgaaatttt
     7021 attaaggata cttaatggtc tattaattaa taaaccatta gtatttaatt tatattacaa
     7081 tattgatttt gcttgtattg gcgttgatag tataacagag gtcttagtag aaccaatttt
     7141 ctttatagta tcaatcacat tttctagctc gtacatatct tttacaatta cttttaaaag
     7201 taagcaatca tcacctgtta tatggtgaca ttctacaatt ctagggtcct ttgcagctga
     7261 ctcaataaat tctgtatatc cattacttgg aagagatata tgaataaatg cctttataac
     7321 tctacctaat gaatctgggt tgacaatagc tttatatcct tctataacac cagactcttc
     7381 taatcttttg actctttctg aaactgcagg agaagttaaa ccaactattt ttcctaagtc
     7441 cttcatagaa attctcccat catcctgtaa aatttctatg attctgtaat ctgtaacatc
     7501 cataaataaa cagtccccct taaataaaaa taattaatgc tataaaactt ttttagaatc
     7561 tatcatttgt gtttttaaat accaaagatt tctagataaa tcaaccttat aaatgtgtgg
     7621 ttttgaaagt cttttgtatt gttcccagat agtacttaat tcatattgta catgattttt
     7681 tatttcaaga acagcttttt tattatattt gcatatgcct tttatataca atggtttaag
     7741 aagctcttta actttgtaat ttgtaaatac ctttgttttc catgtataag taggatggaa
     7801 gatttctaaa ggtttagact catctataac ttcatcatgt aacataatca aatctgcctc
     7861 tgccttattg tcttcgttat atattcttat aactttcttg tacccaggat tatttatttt
     7921 ttctggattc tcagaaatct ttattttagg ttcaagaact cctttttcac aagatgcagc
     7981 taatttataa actcctccaa gagaaggtga atcgaaagat gtaatgagct ttgtacctac
     8041 tccccatgag tttatagtag ctccctctgc tttaagtgat gttatggtat attcgtctag
     8101 gtcattagat gcagtgatgc taatatctga aaagccagca ttatctaact gttttttagc
     8161 ttctttagat aaataagcta aatctccaga gtcaagtctt atacccatag gtttgtatcc
     8221 tttttcagaa atatttttga atacttttat tgcattagga actccactat ttaacacatc
     8281 ataggtatct acaagtagta agcatttgtc tggataaaca tcagcatatg cttggaatgc
     8341 ttcaagttca ttatcaaatt tttgtaccca actatgagct tgtgtaccaa ttataggtat
     8401 atcaaacatt ttccctgcta gtacatttgc agttccagca caaccaccaa ctacagcagc
     8461 cctagctcca tatatacctg catctggacc ttgtgcacgg cgtaatccaa attcaaatac
     8521 agggtctcct tgagctgcaa agcaaactct agatgcttta gtggcaataa gggactgaaa
     8581 attaactatt gtcaacaatg ctgtttcaat gagttgagct tgatacaaag gtgccttaac
     8641 agtaattaat ggctcattag ggaacatgat agttccttct tcaacagcat atatatctcc
     8701 tgtgaattta aattctttta aaaattttaa gaacttgtca gaaaataaat ttaagttttt
     8761 taagtacttt aaatcttcat ctgagaaatg aagattatct atgtattcaa caacctgatc
     8821 aataccacaa actatagtat accctccatc acaagcgttt tttctaaaaa acatatcaaa
     8881 tacaacaatg tcttcatgaa tattcttttc aaaatagcca tttaacatag taagctgata
     8941 taaatcagta agaagtgtta gatttctcat tatttctctc cttaattatt attaaatatt
     9001 aaaaattgta aaaactccca cacttatact aaaacataat atagtacaac tttcaagtat
     9061 aaagtattac ctaactatca taaaattatt taaagaggag gatgattata ataggaaaaa
     9121 tatggtttta tatggtatcg atagggataa taggaagttt aatttctaaa aatatgggtg
     9181 aattaaataa agttatatta agtgaaacat caaaaggtat agagtttgca ataagcctag
     9241 ctggtatcat ggcactctgg atggggataa tgaatatagc aaaagagtca ggcttaattg
     9301 aaaagatagg tcaaaaatta aatcctataa tgagaagatt atttccttct atcccaaaag
     9361 gtcataaggc aatgtcttat atagttatga atattgcctt aaatatgttg ggtgctggaa
     9421 atggtgcaac agcatttggt ttaaaagcaa tgagtgagct tcaaactttg aataacaaga
     9481 aagatacagc tactaatgat atgattatgt tcatggtaat caatatatcc tctatacaaa
     9541 taattccatt tactataatt aaattaagga tggatatggg agctcaaaac ccaagtgaaa
     9601 taatttttac gactttattt gcaaccataa tatctacagt aatagcgata ataacatgta
     9661 aattttttca aagaagatat agataaaggg gatgtagata catggagata ttttcaaact
     9721 tacttatacc aataataatt ttgtacatag tagtttatgg taaatataaa aaaatagatg
     9781 tgtatgatag ttttgtaaaa ggagcgattg atggattaaa agcagcatgg gatatcctac
     9841 catatataat aggtatattt ctagcaatag gaatattcaa aactggtaaa ggtcttgata
     9901 tgttagaatg gctatttact ccaattgcaa atatgatgag tataccaaag gaattaatag
     9961 gtctaataag tgtaaaacct ttatctggaa gtggtgcttt agggatgtat agtgaacttg
    10021 caaatagagt tggaatagga agtttggtag aaaaaatggg tgccacgatt gtaggttctt
    10081 ctgagactat tttttacaca atggcaatat actatggaag tctgaagata aaaaatacta
    10141 gacatacatt atcatgtgct atgattagcc atgttgcagg tgttatagca gctgttttta
    10201 tttgctatgt aatatttgta taatttgttg acaatatggg aaaaatttta taatataatg
    10261 attatataga aacaaatagt aatataaatt acaagctatg aaaagaagag taaataaagg
    10321 ttttttctat cagagagcta gattaggtga aagctagtgt caaaagcttt attgaagatg
    10381 gtcttggagc tttttatctg agcaagtgtg ctagggtaaa acggttggac acgttatagt
    10441 ctactaaggt atctataaaa tgatttctac atttcatgtg aaacataaac attatagatg
    10501 aattagggtg gtaccgtgaa taatctcgcc cctatgttaa ctcataggag gcgatttttt
    10561 attatttaaa tgaaagaatc atatgattac gaacgataaa aaattaggag gtaaataata
    10621 tgagtaaacc gagtttttat gtaacaacac caatatacta tccaagtgga ggattacaca
    10681 taggacatac ttattcaaca gtagctgcag atacaatagc tagattcaag cgtttctgtg
    10741 gatatgatgt aaaattctta acgggaacag atgagcatgg tgaaaaaatt caaaagaaag
    10801 ccatagagca aggaatgtca gagatagagt atcttgatgg aatgataaaa gatataaagg
    10861 ctttatggaa tactatggat atatcttatg atgattttat aagaactaca gaaaaaagac
    10921 atacagatat aatacaaaag atatttacta aactatatga gcaaggtgat atatataaag
    10981 gtgaatatga aggtagatac tgtactcctt gtgagagttt ctggacagaa tctcaattac
    11041 tagaaggaaa taaatgccct gactgtggaa gagaaacata tttagtaaaa gaagaatctt
    11101 atttctttag attatctaaa tatgaagata gattaaaaga gttatttaaa gatgatagct
    11161 tctgttttcc tgctgctaga aaaaatgaaa tggtagcaaa ctttttagac aaaggattag
    11221 aagatttaag cgtaactaga acgacttttg actggggtat aaaagttcct tttgatgaaa
    11281 aacatgtaat ttatgtgtgg gtagatgcct tatgtaacta tataacagca ttaggttata
    11341 tgactgataa tgatgaagaa tttaaaaaat attggcctgc caatgttcag atagtaggta
    11401 aagaaatagt gagattccat acaataatat ggccagcact tttaatggct ttaggtctag
    11461 aagttccaaa acaagtattt gggcatggat ggatactgtt tgctgatgat aaaatgagta
    11521 aatcaaaagg taatgtggtt tatccagaac ctataataga aagatatgga atagacacgc
    11581 ttaagtactt tttattaaga gagtttgcat ttgggcaaga tggaagttat actcatagaa
    11641 attttgtaac aagaataaat tatgatttag caaatgattt aggaaactta ataagtagaa
    11701 ctgtagctat ggttgaaaag tacaataatg gtataatacc aacagcaaaa gtttcaactg
    11761 attttgatgc tgatttaaaa gagcaagctg tatcaactag agaaaacttt gaagctgaaa
    11821 tggataagat gcaattccat gaagcattag agagtgtatg gaaactagtt agaagaacta
    11881 acaaatatat agatgaaact atgccttggg cactagctaa agatgaagct aagaaagatg
    11941 agttagacac agttttatat aatttatgtg aatctataag aataatcgca acactaataa
    12001 atcctataat gaatgagact gctaataaaa tatatgaaca tataggaata aagggtcaag
    12061 atgatataac tacatgggaa agtacaaaaa catttggtct tattggagaa aatgtaaaag
    12121 tatttaaagg tgaaccttta ttcccaagat tagatgtaga aaaagaaata gaagagttaa
    12181 ctaaaatgtt ctctggaaaa cctccagtag aagaaaaacc tttagagcat aaagaagaaa
    12241 ttactattga tgatttagac aaaatagagc ttagagtagg aaaaatatta agctgtgaaa
    12301 aacatccaaa agcaaataaa ttattagtat cgcaagttaa gattggacca gaaacaagac
    12361 aaatagtatc aggaatagct gaatactata agccagaaga tttagtagga aaagaggtta
    12421 cagtagtatg taacttaaaa ccagttaaat taagaggtgt agaatctcaa ggtatgatat
    12481 tagcagcagg tgatgatgga gacccatatg ttttaccatt tacacaaggt gctaaagatg
    12541 gatgcgaggt tcgttagtag gcaattaaag agtaaggaga ttaaagatgt tatttgactc
    12601 acatgcacat ttaaatgatg aaagttttga tgaagataga gatgaactta ttggttcatt
    12661 aaaagataaa ggtgtagatt tggttgtaaa tccaggagca gatatagata cgtcgataac
    12721 agcaattgaa cttgcgaaaa aatacgactt tatatattca gcagttggag tacatccaca
    12781 tgaggtatca aaactagatg atacagcaat agaaattcta agaaaacttg caactgagaa
    12841 tgaaaaagtt gtagctattg gagagattgg attagattat tattatgatt attctccaag
    12901 agaagaacaa aaagagtggt ttaagaagca aattgaatta gctaatgagc taaagcttcc
    12961 aataataata catgatagag atgcacatgg agatactttt gagataataa agaatactaa
    13021 gagtcctgaa ataggatgtg tacttcattg ttatagtgga aatgtagagt tagctagaga
    13081 atatgttaag atgggttgtt atatatcaat tccaggcacg gttacattta agaataataa
    13141 aaaaactaga gaagtagtaa gagaaatacc tctagaaaga ttattcatag agactgattc
    13201 accatatatg tcaccggagc cacatagagg aaagagaaat aatccttctc aagtatcttt
    13261 tgttgctgat aagatagctc aggaaaaagg tatatcttat gaagaagtat gtagagttac
    13321 aaaagaaaat gcaaagaaat tttttaatat aaaatagaca aattaagtcc tataatggta
    13381 tataaaataa gtcattataa gtatagaatg agggtgcctc aaaatgaatt ttttagttca
    13441 tgaggtactc ttttttatat gaaatcaaat atattttcgt catttcaaca atgaaaaata
    13501 agtttatcct attttgatac agtctatttc tatttattta attcatattt taaaatatat
    13561 ttttttaaca ttgttaaaaa agaatttaca agatattcac tagaattaac tcaactataa
    13621 tattcattta acttaccttg tttattatat tattaaagag aagtaaacga aggacagatt
    13681 aaggaggcta aattttgtat acagttgata gtactaagat attgataaat atgaacttag
    13741 agaaactaga aaagatatac tcaatgttaa agtatacatc aaatgtttct ataattaaag
    13801 aacctaagtt ggctacagta atggaagagt taatgaaaat gtaaaaaata caacatttaa
    13861 tttaggggat atattagtta ctgaatgtag tgtagaggta gatgaaagtt tgggttacgg
    13921 aatagttgca gaaaaaacta ataatttaaa taaagcagta agtttattta cctcaagcac
    13981 tattaaagtt ggtatatatg atgaaagaag tagtgtaaaa gaaaataaaa agcagattta
    14041 gtttcagtag atattaacag tgaatatcca aagcttgtaa gtattattgt aaatggaaaa
    14101 gcagtttata aaagggaggt ataaagattg ttaacagagt tacactgtca tacaaatata
    14161 tcagataata attttactac tgaagaaata ataaaaaaag cagcagaaaa gaatataaat
    14221 atcttagcaa taacaaatca tgacacatta tctggattgg atgaagccat tgtgcttgga
    14281 gaacattatg gaataacaat aataccaggt atagaaattt cagcttatga ttatataaat
    14341 agaaaaagag ttcatattct tggatataac atagatttaa acagtcaaga aataaaaaat
    14401 ttgtgcaatc caatggtatg tgacagacac aaagcatctg ttaagatggt aaataaaatt
    14461 atagatttag ggtacaaaat atctctggag gatgtaaaga aatattcatc aaagactgga
    14521 atatttaaac aacatataat gaaggctctt atagataaag gatatacaga taatatatat
    14581 tcaagtctat ataaagaact gtttcataga ggaaacggta aggtatatgt atctttaaga
    14641 tatgtagatt atagagatgc aataaaagct ataaaaaatt ctggtggaat ttgtgtgtta
    14701 gctcatccgg gtcaaatgga taattttagc gctattgaag agatggtaaa agtaggatta
    14761 gatggaatag aagtatatca tccatctcat aacaaagaac tagaaaaaga atcgctttct
    14821 tatgctaaga agtacaatct agtggtcaca ggaggctcag attaccacgg attttattct
    14881 caacataatt atgaacttgg aagtaagagc ttaaataaag aagatttatt taagtttagg
    14941 ttagctttag gaggggtatt ataaatgtct tttttacaag taaaaaatgt atgtaaaagt
    15001 tatggacaag ttaaggtgtt aaaagatata tctattgata ttgaaaaagg agagtttatt
    15061 tgtttactag gaccaagtgg ttgtggcaaa agcacactgc ttagaataat tgcggggctt
    15121 gaggataaac atggtgggaa aataataata aatgatagag atatgactaa ttcaccacct
    15181 gaaagtagaa attttggtat agtttttcaa tcatatgcat tatttccaaa tatgaatgtt
    15241 tacaaaaata tagcttttgg actagaaaat aaaaacataa gtaaatctaa cattgataaa
    15301 aaagttaaaa aagttctaga agttgtagaa ttaagtggat atgagaaaaa atatccatca
    15361 caattatcag gtggacaaca acaaagggtt gcattagctc gtgcgattgc tttagagcca
    15421 gactttttac ttcttgatga acctttatct gcattagatg caaaagtaag acttaaactt
    15481 agggagcaga ttagaagttt gcatagaaaa ctaggcatta caactataat ggtaacgcat
    15541 gaccaagaag aagctctttg tttagctgat aagatggttg ttatgaatag aggagaaata
    15601 atacaagttg gaactccaaa ggaagtatat aaaaatccag aaacaccttt tgtagctgat
    15661 tttataggaa caataaattt tatagataat ggtattaata agatagctat tagaccagaa
    15721 gacataaagg tagagttcaa tagagattct aaagataaag atataaaaga gggagagatt
    15781 ttggatatag aatttagagg atttaactat agaattacag ttgagtattg ctctaagcaa
    15841 atgaagttag atgtagtttc aaaagttgca gaacaaatga aactgtgtat aggttctaaa
    15901 ataaacttta agatacctaa agaaggaatt gtacaatata aatcagaggg atgtgcttaa
    15961 tagctaggga tgaataaatg ataacatcaa aaaataaaag aagaataagt gatagcacaa
    16021 tacaaaaata tttcttgatt ttttcagtaa ttgtactaat agtatttata ttatttccgt
    16081 tagcatcatt attaaaaaat gcatttatgg atacaagtgg aaattttata ggaattttaa
    16141 actttagtaa atatattgag aatccaagtc ttatcgcatc atttaaaaat tcaatttttg
    16201 tatctatagt ctcatcttta atatcattat gtttagcatt tatatattca tacgcaataa
    16261 caagaacaaa tataaagttt aaaaactttt ttaaaactat gggaatgttt ccactttttg
    16321 caccaactat gttatatggt atttcactta tatacctttt tggaaataag ggaatcttta
    16381 caaccatggg tctggaagta ccactatatg gtccattagg aataattatt tctcagattc
    16441 tatttacatt tccacaagct tttttaatat tatctgtagc actttcgatg gctgattaca
    16501 gactttatga agcagcagat agcttgggtg ctagtgaatt taagaaattt tgcaaaataa
    16561 caattcctgg tataaagtac tcattactta gttcattctt tgtatccttt atacttgcat
    16621 ttacagattt tggagcagct aaggtagttg gaggaaacta caatgtactg gctactgaca
    16681 tatataaaca agtagttgga caatttaaca taccaatggg agctactgtt tctatggtaa
    16741 tgttaattcc tgtactaata gcatttacat tagataagat ggcaagtaag aaacaaggta
    16801 tgaccataac tgcgaagtct atgccatata agattaaaga aaacaagtct agagatagag
    16861 cgtttttaat agtatgtagt cttataacgt tgctaatttt tattttgata tttgtttcag
    16921 ttataggttc agttataaaa ttatggccat ataatttaag ctttacaatg gaacactata
    16981 catttaaagg tattttggga agtggaataa aaacatattt aagcagtttg aaaatatcaa
    17041 ctttaacagc agtatttgga actatatttg tattttttag tgcatatatg atagaaaagg
    17101 tggataagtt tcctaagtta agacaaatag cttacttttt atcaatgata ccaatggcct
    17161 tgcctggctt agttttaggt atatcatata taactttttt taactcagca agtaatccac
    17221 taaatttttt atatggaagt acagcaatac tagttatagt aaatatagtt catttttatt
    17281 cagtttgttt tataacttca aactcatctt taaaaatgtt ggatatagag gtataaagtt
    17341 aaaagaggaa ggctatccag tagaagtagt atttccaaaa gaaggttctg gatgagatat
    17401 agaagcaaat gctcttgtga aaaaagataa tataaaagaa gcctcaaaag tatttttaga
    17461 ttgggcaata agtaaagatg caatgaatga atattctaag aactatgcag ttactactat
    17521 ttctacggga aatccaatac cagaaggatt tcctaaaaag ccattagagc aaatgataga
    17581 taatgattta aaatcagcag cgaaaaatag agaagatata ctaaataaat ggatatcaaa
    17641 atatgatggt aagacagaaa aagagagtta agcctgacaa taaaatttaa tacaaaaagc
    17701 gcctagaata taaattttat atctaggctc ttttgatgtg tttgtttaaa atgcatattt
    17761 ctatataaaa ataaatagtt tagtaccttg attaaattaa ataaaaacct taaaataaag
    17821 agatgtaaag aaaaattaaa aacgaataaa aggtgaattt atatgataaa agaaataata
    17881 gtagtagagg gtagagatga cgttacagca gttaagagag caatagatgc agaacttata
    17941 actacaggtg gatttggatt tccaaaaggt gtaatggagc gtataaaagc tgctaatgaa
    18001 agacgtggtg ttataatatt tacagaccca gattttgcag gtgaaaaaat aagaaaaaaa
    18061 atagcatcag aagttccagg ttgtaaacat gcatttctgc caagagagga agctaaaaag
    18121 gatggagata taggtattga aaatgctact cctcaaagta taatagcagc tttgaataag
    18181 gttagaactg aaaatacaga aaaaagagat gaatttaagc aaattgactt aattagaaat
    18241 ggtcttatag gtaatgaaga agcatcactt agaagagatg cacttggaaa aatacttgga
    18301 atcggatatg gaaatgcaaa acaattttta aatagattga ataattatgg agttgaaaga
    18361 gaagcattta tagatgcatt aaaacaaata taaatgtaat gtttaatata tgaaaaatat
    18421 gtatataaaa taaattgtgg aattacggtt aatttaagat aaattattta taatatatac
    18481 cttattttaa atcaatgtaa atacatataa ataagtataa ttaataaaat taaatatcaa
    18541 aataagttaa aaaggagtaa ataatggata gactatcttc acataatgca acaaaggaag
    18601 tagtacaaaa atataatttt aagttttcaa agtctttagg tcaaaatttc ttgatagata
    18661 gtaatataat tgataaaatc ttatctggag ctagaatcac aggaggagat aatatcatag
    18721 aagtaggacc tggtatagga actcttactc gtgagatggg taaaatagca gaaaaagtag
    18781 tggctataga aatcgataga aatctaatcc ctatattgaa agataccctg tcagatttag
    18841 agaatacaga ggttgtaaat caagatatac taaaagtaga catacaggaa ttagtaaaag
    18901 ataaattaaa tggtggacca gttaaacttg tagcaaatct tccatattat ataactactc
    18961 caatagttat gaagttttta gaggaagata tacctgtaac agacatagta gtcatggttc
    19021 aaaaagaagt tgcagataga atgaatgcta ttccaggtac taaagattat ggtgcattat
    19081 ctatagctgt tcaatactat tgtgatacag agattgtggc aaaagcccca agacatatgt
    19141 ttataccaca accaaatgta gattccacgg ttataggctt acatgtaaga gataaaagaa
    19201 aatatgatgt tcataatgaa gaaatatttt ttaaaacagt aaaagcatct tttggacaaa
    19261 gaagaaaaac tcttcttaat tcgttgggag gtcttggctt tcttaataaa gatgaaataa
    19321 gagaaatatt aaaagaagct aatatagacg aaaaaagaag gggtgaaacg cttagtatag
    19381 aagagttttc agttctttca aatataataa atacaaaagt atcttctaaa tagaaggtac
    19441 ttttttttat tttgttaaca tatattgttt agagaaactg tgttaagggg ggattgcagt
    19501 gggttctaaa agaaagttta aaagagacta tataatacta gaagctaaag acataaactt
    19561 tagatacaaa gaacgagtac tgccaaaagc ttttgcaaaa gttgaagtaa acgatgaaaa
    19621 agcaattatt gcattatatg tagaaaatct aaaatatgtt aaagatgggt ataaagcagt
    19681 agcaataaaa gatgaccatg gattaataga cttaggaaat ataattttaa atgaacaagg
    19741 aagaggtgaa tttgttttag atttagaaga ttatgatgat gagataaaag gtattgcatt
    19801 attgtatgaa agaaatatac ctttaattgg atttaaggga aataagcttg aaaattatga
    19861 ggatatatta ttccaagagg tagaggaaga agaatatgaa gaattggaag aagaagacga
    19921 agaggtagag gataatgagg aaagtaatag agacgaagat attgaagaag aagaatatat
    19981 tatagaagaa tatgatgaag atgagtatga agactattgg gaagatgatg aagatattga
    20041 agaaggagaa ttaaaagcaa gaacggaagt agaagattct agtaatgaag aaatagaaga
    20101 gttcaataat tacaaggaaa tagaaaatta taatagggtt aaattacagg aagaatatat
    20161 agacatagaa tgtgaagagg atgaagaaga ggatgaagaa gaagtttttg aagtaaatag
    20221 agaagatgac aggtttgttt cttcaaaacc tactaaatca aagaaagttc aaaaagagca
    20281 gaataatatt gaaaaaataa aaagagtcaa tggagtaagt caaggagaga gtggaaataa
    20341 acaaaccagt acattactta tgccaagaca aataaaaaaa ggtttgaaat tatttaaaga
    20401 agtaaaacct tttgtaacag attatataga taagacaaga tggtggaaaa tagagataaa
    20461 tcctacaaca ttatgtggat atacaatgcc ttatttagga tatttaaacg tgttgaatta
    20521 tactatgtat agtgatgcag ttttacattc atataaatat agacactatt tatttggagt
    20581 tcagtatgat gaatataata agagaaaaca ttatatttat gctatcccag gaaatagaaa
    20641 tgaacagcca gacaatggaa gcacaggatt tttaagatat caggcttgtg ataatagaac
    20701 aaatagttta gggtattggc tatgttttat agattctaga caaagaaata tagttaggta
    20761 aaaataataa aaataaaaaa atttagactc aatttttatt ttactgaaaa aattaatgaa
    20821 atgcagtaca aaactttaaa aactattgat aatatttaaa tattacacta caatatatct
    20881 tgaaatacct attatattat ggaggaaaat tatgataaac gagcaaagaa ttttaaatga
    20941 gtttcttgaa ttagtacaga tagacagttt atctttaaaa gagggaaatg ttgcgaaagt
    21001 attagttaaa aaattagaag aaataggttg ttcagtagta gtagacaatg ctggtgaaaa
    21061 agcaaatgga gaaactggta atataatagc tacactaaag ggaaataaag aaggaaaaaa
    21121 aatattattt agttcacata tggatacagt aactccaggt ataggggtaa aacccatagt
    21181 ggatgaagta aacggaataa taaaaagtga tggtactaca atattaggtt ctgatgataa
    21241 agcaggtata gcagctatat tagaaggatt aagatatata aatgaaaata acatagaaca
    21301 tactgatata caagttgtat tctctatatg tgaggaatgt ggattagttg gagctaaaaa
    21361 tttagactat ggaaaaatag actctgaata tgcttttata ttagatagtg gtggttctcc
    21421 aggggaaata atagtaaaag ctcctgcaca agatgtaata aatgttaaga tattaggaaa
    21481 gactgctcat gcaggtcttg aacctgaagc tggtataagt gctataatgg tagctgccag
    21541 agcaatagaa aatatgaatt tacttagaat agatgaagaa acaactgcta acataggaat
    21601 tataaacggt ggaacagcta caaatatagt aacaggagaa gttaatatag ttgcagaagc
    21661 tagaagttta aaagaaaata aattagatgt tcaaactaaa cacatggtag agacttttga
    21721 aaaagctgca aaagattttg gagctcaaat tgagatagat gtcaatagag catatacacc
    21781 aatagatgtt agtgaagatt ctgaaataat aaaacttgca aagaaggctt tttcaaactt
    21841 aggtatagaa ggtcacactg aatctacagg aggaggtagt gatacaaata tattaagtaa
    21901 gaatggtatc gaagctataa ctttaggaat cggtatgaaa aatgctcata cactaagtga
    21961 acatatagct ataaaagatt tatatgattc tgctaaaatg gtagtggaga taataaagga
    22021 agcataaatt taaataatag tgtataatat atatatcgcc tagcttaagc taggtgattt
    22081 ttcattttat agaagattga taatctctat tgaaagcaaa gagtatacat ttgcatataa
    22141 gagagtgttt aatttatatt cagatgtagg ttcttaataa tatttagatt gtttcataag
    22201 ggaggaataa atatggaaac aaggtatgaa gaagcaaata aaataacaat acaatcaata
    22261 ctttggaatg tagtattaac aataattaag gttatagctg gtgttattgg taattctagt
    22321 gctatgattg cagatggatt acattcagca tcagatatta taagttctat aggagtatta
    22381 ataggcaact atgtatcttc tagacctgga gatagagagc ataattatgg tcatgagaaa
    22441 gcagagacat tagtgtcatt tgtgttatca atactgctta ttttcgtttc tataacaata
    22501 ggtatagagg caattaaatc tttatttaac ttagatgcat tgagtgttcc atcaatattg
    22561 ccattagtag tatcagttat ttcaatcctg ataaaagagt atcaatatag aataacaata
    22621 aaagttgcta aaaagataaa ttctccagcc ttaaaagctg atgcttggca tcataggtca
    22681 gatgctttat cttcagtagc tgcttttata ggtataggtg gttctatttt agggtttaag
    22741 ccattagacc caattgcatc agttgtagtg gctatatttg tggctaaagt aggaattagt
    22801 atacttataa gttctgttaa tgaattgatg gatgtttcag ttgatgaaga ggagataaaa
    22861 gaattaaaat ttattgtagc agatacagaa ggtgttaaaa atcttggaga tataaagact
    22921 agaaaacatg gagctatggc atatgtagat ttaactatat gtgtggatga agatttgact
    22981 gttaagcaag gtcatgatat tgctactaag cttgaaaaac atataataaa acatatggaa
    23041 tttgtaaaag gcataacagt tcacgttgaa ccatgtacta attgccaagg aaataagtgt
    23101 aataattaat taaaacttaa aaaaaagtgt aaaaagttat ataattgttt tatgattata
    23161 aactctaggg gtggttaaat gagcaaaaag agaaaactaa agaaaaaagc tgcaatattg
    23221 ataggagtgg ttgttttctt tataatatac tttatatcct ttagaatagg aataaatatg
    23281 gaaaaggata aaagtgaagt gccaaagaag gtagaaaaag aagaagaaga taataggtct
    23341 ttaaggactc aaataaaaga aaagaagaag gtttatatat cagataaaaa tatagaaaac
    23401 ataaaaattg aggaagatat gtgggatgaa ataaagttat ttttctcaga ttttaagaaa
    23461 gtaagaaata ctacttcttc ttatgaagca gtctatgaag gctattctga tgatggagtt
    23521 aaattttcta ctgaccttaa cttttttaga gtatatactg taaacaaaga agaatattat
    23581 aaagtgccag ttagttctaa ggatgctttt aagaaacttt tagatgagag tatatatact
    23641 tcgtttgacc ttctaagtca ttataaagat tggaaagagg ttactataac ttatggtaaa
    23701 gaaattaaaa aagttcatag atggaagttt gatgatttag cacataagat gatttcaaaa
    23761 agggttgtag gaaaagttca acctgaaaaa agtaaggaaa gaagtgacta taattttact
    23821 ataaatataa aaggtgataa ttttgatgta aaagttgata caatgggaaa agattatgta
    23881 aaagttactt ctaagaaaaa tgtatcttac tatgaggttc atacaagttt atttgattac
    23941 cttaaaaatg aaatatttga aattggaaag aaataatact ttaagaaggc tatcaaatta
    24001 gatatttgat agcctaaatt gttttattta ttatttttca accaacaagt ctgcaacctt
    24061 ataaattgga ccagcaccag cagttattac taaatcattg tccttaacat tttcacgtaa
    24121 gtattttact atatcttcaa attcttttat atatatggca tctacattgt tttgatataa
    24181 tttctcaacc aagtccttag aatgtatatc tccggggtct ttttctctag cagcatatat
    24241 atctgttatg ataactttat cagcagcata gaatgcttct gaaaattcac ctaaaagaga
    24301 ttttgttcta gtataagtat gtggctggaa gatacaccat aaagtagatt tttttaattt
    24361 tttggcagca gctaaagtag cttttaattc agttggatga tgtgcataat catctactac
    24421 taaagcattc ttataatacc ctttagtttc aaatcttctt ccaacgcctt tataaatttt
    24481 tatatttttt cttatagtct ctaaatcaat accagaaaca agagctgcca ttatagcaga
    24541 agaagcattg tatatgttat gaagaccata tacagaaagt tcaaattctc ctaaatctct
    24601 tccttgatac tctattctaa atattccatg accactattg tcaaagtgaa tatcttttat
    24661 tacagcatca ttgtcagaat ctctaccgta ttttataata gtagctttaa catcatacaa
    24721 tatgtcatca atattttcat catcaccatt tattatgaaa tagccttctg gaggtaataa
    24781 ttttccaaat ttgttaaaag aagctttgat ttcatctatc ccagagaaat aatcaagatg
    24841 gtcctcttca acatttaaaa ctatagatat tttggggtta aaattaagga aactatctac
    24901 atattcgcat gcttcagtta taaagtggtt ggaattacct atcttaacat taccacctat
    24961 catacttaag ttgccaccaa ctagtatagt tgggtctaag tctgcatatt caaagattgt
    25021 agataacata gatgttgtag aagtttttcc atgtgttcca gaaactgcta tagaattttt
    25081 atattccctc atgatttggc ctaaaaaagt cgctctgttc attactaatt tgtttttttc
    25141 tttagcagcc acaagttctt cattgtctgg gtggactgct gctgtataaa caaccatatt
    25201 tacatcatct gatatattat cttttttctg accaatataa atagttgccc cttggtctct
    25261 aagtttgtct agtaggtatg attcgtttga atccgaacct gaaacttgat aacctttatt
    25321 gatacatatt tcagctaatg cactcatgct gataccgcca attcctataa agtgtatatt
    25381 cataataaaa ccacctttct ttttaattaa gtcctacaat atgaactatt tctgtggtat
    25441 aataatataa tgttcaatat tttataatta atatgcatat aatattatat gtattttatt
    25501 tttgaatata ataaaacata agtaatatta taccacaata agaattgtta tgcattagtt
    25561 agtttaacgt tatataaagg tacttgtagg aggaaataat aatgaaattt aaaagaacag
    25621 agagaattgg agcaatagtt aaaatactgt ctgataatcc aaataaaata tatacattaa
    25681 gttattttac aaatcaattt aatgcagcaa aatcaacaat aagtgaagat ttattagttg
    25741 tgaaaaatgt atttgagaag ttacacttag gtaaggtcat aactatctca ggagcagcag
    25801 gaggagtaaa atatatacct aaaacttcta tagcagaaaa tgcagagttt ttaatggagt
    25861 tatgtgagag aatatgtgac aagtctagaa tattatctgg tggattttta tacttgattg
    25921 acataattta tgaccctaca atagctgcta agataggaaa gatatttgca tcaaatattg
    25981 agtatgtaga tgcagattat gttgtgacaa tggaaacaaa aggtatacct atggcactta
    26041 tgactgcaaa agctatgaat ttacctctag ttataataag aaaagatata aaggtatcag
    26101 agggtcctac acttagcatg acatatgtga gtggaaacag ctctaaagtt gaaagtatga
    26161 gtttgccaag aaaagctctt aaaccagata gtaaagttat aataatagat gatttcatga
    26221 gaggtggagg tactataaaa ggaatggtag accttatgaa tgaatttggt gcagaagtta
    26281 taggtactgg agtattcata tctacaacga atccttcaga aaaaatggta aaagattata
    26341 tttcattaat tcaattggat gttaatggag ataaaatagt agtagaacca aacttaaaga
    26401 cttttaaaga tgaatataga aatgaagatt tagatgaaga agaagattca gaatttgaat
    26461 ttgagataga tgaagattaa taaaaaaaat atttagaaaa atatgtaaaa ataaaaagag
    26521 gatatcccta gttgttcata gaattattta aaaaacagtt tatattaatt tattccagcg
    26581 ataataattt taatataaat taatttctgt caaaatcaaa gggggatatt ttggtatgaa
    26641 gataactgac gtaagagtaa gaaaattaac agaagaaggt aagatgaaat gtatagtttc
    26701 aataactttc gataatttgt ttgtagtgca tgatataaaa gttatagaag gccataatgg
    26761 gctatttata gcaatgccta gcagaaaagt aggcgaagga aatttcagag atatagctca
    26821 tccaataaat gcagaaatga gacaagtttt agaagatgca gtattacaag catatcatga
    26881 agcattagtt caatgggaag tagctgctga ataataataa atatataaaa tggagagagc
    26941 ccgaacattt aggctctttt taaatgtaga atttctatta aaatatgtac tttttagtaa
    27001 aaaagtgcta tattattagt gataatgtat atgttgtata caaattgtta gataaatgta
    27061 ttataatgta tattgattaa gagaataata cgaataaaat taaattagat tgaatggagt
    27121 gtatcaatga actttaaagc tataatcctt gctgctggca aaggaacaag aatgaagtct
    27181 aaatacccaa aagttataca taaagtatgt ggaaaagaaa tggttaacca tattatagat
    27241 gtttcaaaaa aatcaggggt aaaagatact gtcgtgattt tagggcatga agctgatgta
    27301 gttaaagaaa agcttgcaga agaaattata atagccatgc aaacagaaca gcttggaaca
    27361 ggacatgctg tgaagatggc taaagaatat attaatgatg aagatacaat agttgtactt
    27421 tgtggagata ctccacttat aaaagaagag actctgaaga gactatttga atatcatata
    27481 gaaaataaat atcatgctac agttcttaca acaagagttg gaaatccaac aggttatggt
    27541 aggataataa gagataagaa gggtgatctt cttaaaatag tggaacaaaa agatgcaaat
    27601 tcagaagaaa aaatgataag tgagataaac tcaggaatat attgttttaa tggaaagagt
    27661 cttagagaag cactagattt gctaaataat aacaattcac aaggtgaata ttatttaact
    27721 gatactgcta aaataatgag agataaagga ttaaaagttg gtgcatttgc aggttcaact
    27781 attgaagaac ttatgggcgt taattcaaga gtagaattat caaaggcaga agaaattatg
    27841 agacgaagaa taaatgaatc tcatatggta aatggagtga ctataataga cacgaactct
    27901 acctatatag aatctgatgt tataataggt aatgatacca taatatatcc aggtgttatg
    27961 ttacaaggaa aaacaaagat aggttcagat tgtataattg gaatgaatac atctataaca
    28021 aattcagaaa taggtgatgg tacagaagta aaaaactcaa ctataattga tagtaaagtt
    28081 ggagaaaatt ctactgttgg accatatgca tatctaagac caaagagtga cttaggaaat
    28141 aatgtgaaaa taggcgattt tgtagaagta aaaaatgcta ttatagaaga tggctcaaaa
    28201 gcatctcatc tttcttatat aggagatgca catgtcggca aaaatgtaaa tattggatgt
    28261 ggagtagtat ttgtaaacta tgatggtaaa aataaattta aatcaatagt aaaagacaat
    28321 gcgtttatag gttcaaattc taatttagtt gcaccagtag ttgtagaaga aaaaggatat
    28381 atagcaacag gttcaacaat aacacataat gttccagatg gtgctttggc aatagcaaga
    28441 gaaagacaag ttattaaaga aggttgggta gaaaaaaaga atcaaaaaga caatcaaagt
    28501 aagtagttat gtagtttatt attttggcta aaaatttagc tcgaaattat tataaattat
    28561 attcattagt attttaaaat tttcaggagg gttacataaa tgaatactag cggaagcgag
    28621 attaaaatta ttgcaggtaa ttcatcgaaa gagttagcac aaaaaatagc tgactatata
    28681 ggtgtatcag tactagattg tgaagtaggt acatttagtg atggtgaaat atgtgtaaac
    28741 atgaatgaga cagtaagagg ttgtgatgtg tttgtagtgc aatctactaa cagcccagta
    28801 aatgataact taatggagtt attaatctta attgatgcat taaagagagc atcagcaggt
    28861 agaataacag cagttattcc ttactatgga tatgcaagac aagatagaaa ggctaaggca
    28921 agagatccaa tcactgctaa attggttgca aacttaataa ctgctgctgg agcagataga
    28981 gtattaacaa tggatttaca tgcagctcaa atacaaggat actttgatat accattagac
    29041 cacttactag gtggaacaat attagcaaat tattttaatg aaaagaaaat agaagattta
    29101 gtagtagtat ctcctgactt aggaagtgtt actagatcaa gaaaatttgc taatacttta
    29161 aatggagaag ttccaatagc tataatagat aaaagaagac caaaagctaa tgtatgtgaa
    29221 gttatgaact taataggtga tgttaaaggt aaaaatgtta tactattaga cgatatgata
    29281 gatacagcag gaacaatagt taatgctgca aatgcactta aagagtttgg agcaaaagat
    29341 gtttatgctt gttgtactca tggtgtgtta tcaggcccag ctattgaaag aattgctaat
    29401 tcagagataa gtgagttaat agttcttgat actatacaac ttcctgaaga gaaaagaata
    29461 gataagataa agataaaaac agtagctcct ttatttggag atgctataag aatgatattc
    29521 tctaatgaat cagtaagtaa attattctaa tttattgtat ttatgagagt tgtttaaaag
    29581 gatataagcc ttttgagcaa ctctttttga tttacttatg gaatgttatt tttctcttgt
    29641 tagaaaggta tctattattg tagaaagaga ttatagttta aaatttatgt atatttaatc
    29701 aaaataaatt taataaaaga tatattattc aaaatattat gaatataaaa aatattacaa
    29761 aaaagtattg aaaaaattca gattatgtag tattatgtaa atataaataa agaaagaggt
    29821 gtttccaatg ggaaggttag aagatgaacc cctaataatt aaatgattca gtcacaatct
    29881 aaagtgaata taaaaatcta ttgaaagttt atttataaga attgaaaata gtatctattc
    29941 tatctttagt gtttgtgaga gggttctgga ttatataaaa ttactgtaaa gaaagtaatt
    30001 ttgcacaata agcatatctg taaatgaaga gtttcgttta tataatgatt gtggctgaat
    30061 cataactata atagatagaa tgtttataat agatgatttt ataaaatact atattgtaat
    30121 agcttttagc tttcaaataa atattagcaa aggatggaaa tgacaatgat aaaactaaat
    30181 gataatttat aaatatctcc ttacgatata taataattgt agggagatgt ttcttttttt
    30241 gtatagtata attttttcta gaaattctgt ttcaatatgt aaaaagttgg tatatataaa
    30301 tagtataaac tgtgttgcta aaatatggta gatattatat aatataagtg gatatgtata
    30361 tacattatga gttatataat tttgaattta ataaaataga aacgttgatt tatgttctgt
    30421 aatgtgggca ccttggagca tattgagtta gtggtgcaac cggctatgaa attgtattta
    30481 tttatagata ctattatttt catagctttt tttatttaaa aaatggttat atattagaaa
    30541 taaatttggt tagtacgttt aaataatttt acttggattt ttaaccagat atattataag
    30601 caagtattaa ttaaaaagtt gagggggaat aaaaatgaag ttaaaaaaga ataaaaaagg
    30661 tttcacttta gtggaattat tggtagtaat tgcaattata ggtatattag cagtagtggc
    30721 agttccagct ttatttagta atataaacaa ggctaaggta gcaagtgttg agtctgatta
    30781 tagttcaatt aagagtgcag cattatctta ttattcagat actaataaaa taccagttac
    30841 accagatggt caaactggtt taaatgtttt agagacttat atggaatctc ttcctgataa
    30901 agctgatata ggtggagaat ataaattgat taaagttggt aataaattag tattacagat
    30961 aggtaaagat ggtgaaggag ttaccttaac agaagcgcaa tcagcaaaat tattgagtga
    31021 tataggtaaa gataaaatat atacaggtgt tacaggagat aattttggag agcaattaaa
    31081 agatactaca aaaatagata ataaagctct atatatagta cttatagata atactgtgat
    31141 ggattcaaca aaatagttaa aacaatattt ttataaaaat attgtaaatt taatgaaaaa
    31201 tataatataa aagacaggaa gaaaatcttc ctgttttttt atactatttt ctttaatgtt
    31261 caattatgaa tgatgatata attgagatag taaaggagtg aaacctgtgg ctaaaaaagt
    31321 tagaatagga gacaaactgg tcgaaaaagg atatataaca gaagaccagc ttaaatgggc
    31381 attatcagaa caaaaaaaca gtggaaaaag actaggggaa tttctagtac aagaagggct
    31441 tatagatagt aacttattaa taagtgtatt aaaagaactc ttagatatag aaagcatctt
    31501 tttagaagga acagaaatag atacattagc tacaaagatg gttccagaaa atatatgcaa
    31561 aagatacact gtatttccat ttaaaattga tggaaataaa atatgtctag ccatgtcaga
    31621 cccacaagac agagaagcag ttcaagatgt aagacgtatg tctggtaaag acgtagagat
    31681 atttatatca agcacagaag atataaacaa agcaataggt catgcttatg cacattcaga
    31741 aataaataag gcaatgactg agtacaacaa aaatagaact ggtggagtaa gagaaacagt
    31801 aatacttgaa gaagatgtaa atgctgctcc aatagtacga ttagtaaata acatactaga
    31861 aaatgctgtt agaatggaag caagtgatat acatatagaa caaagtgaaa attacatgcg
    31921 tgttaggttt aggatagatg gaatgttaag agaatatatg aggatgaact cagcaccata
    31981 taaggcagta atcagccgta tcaagataat gtcagatata aatatatctg aaaagagaat
    32041 accacaggat ggtagaatct atttaaaagt agataataaa cccatagact ttagggtttc
    32101 tacaatgcca actaacagag atgaaaaaat agccatgagg gttcttgata agagtaattt
    32161 tatggttagt aaagaagtac taggaataga tgagcatggc tctaagatat atgatgaatt
    32221 aataaacact ccttatggtc ttatattggt tgttggccct actggaagtg gaaaaactac
    32281 tacattgtac tcaatgctaa atcaactaaa tacagaaaat agaaacctat taacaataga
    32341 agaccctata gagtatgaat tacctggtgt aaatcaatct caaataaatg aaaaggcagg
    32401 gcttaccttc gctagtggtc ttagagcatt catgcgtcaa gacccagata taataatggt
    32461 tggagagata agagatactg aaacagcaga aatagcaatt agagcttctc ttacagggca
    32521 tttagtctta agtacattac atgcaaatac agcagttgga gcaatttcac gtcttttaga
    32581 tatggatgtg gaaagttttc tgataacttc atctgtttta ggtgtaatat ctcaaagact
    32641 tacacgaaaa atatgtgagc attgtaaggt ttcatatgaa gcagatattg gagaaaaaaa
    32701 ggctcttggt attgatgtaa atgaatcagt aactatttat agaggaaaag gttgtgaaag
    32761 gtgtaataat actggatata aaggacgtct aggtatattt gaaatgcttg aaattactcc
    32821 agaaataaaa gagttaatag attcatctgc aaatcaaaga gaaattttaa agatggctag
    32881 aaaacaaggt atggttagct taaaagagga tatagttaaa aaggttttaa atggaaagac
    32941 aacagtagaa gaaatgatta gaataatttt gatgactgat taaaggatga tattatgaaa
    33001 agttttaaat acacagtaat aaaagaggac ggaaaaaagc aaactgatgt gattgaagcc
    33061 aacgatttta atgaagctag aaatctcctt agaaagagaa atcttagagt tattgaaatc
    33121 aaagaaagta aaaataaaaa tataagatta tctagtagaa agagaaaaaa agacttagga
    33181 gctgaccaga taagccactt ttgtagacag tttgctatta tagtatcttc tggtataaat
    33241 agtatttctg gattagaaac attagctaga aggtcaacta acattacatt aagagaagaa
    33301 attaatcgta tagtggcaga aataaaagta ggttctacta ttgcagattc aatgctttca
    33361 tcaaaatcaa agtttccaaa gttacttggt gctatggtag ctacaggtga agctacaggt
    33421 aaattagatg aagtattaaa aagtatggct tcattttatg caagtgaaca cagggttaaa
    33481 caaaagctta gaaatgctgc aacatatcca ttaatagttt tgatttcttc atttataatg
    33541 atttttatat ttacagcatt tatggtgcct aagatgatta attcaattac aacagtagga
    33601 gcaactcttc cacttataac aagaattgtt atggggtttg gtatgtttat gaagaagttt
    33661 tggataatag tacttttagt tattatatta tttatctatc agtttaaaaa gtatctaaaa
    33721 acgccaattg gaagagctca taaagataga gttataaaca agatacctgt tttaggaaaa
    33781 ggaataaact gtatggtagc tacacggttt tcaagagcat tgtatctatt tgtatcaaca
    33841 ggatatccat tggttcaagg gcttgattac attatagata gtgtaaataa caccatggca
    33901 gaaaagattt tagtatcagc taaagacgga ataacaagag gagaaggttt agcagaaaat
    33961 ttagagagat atacatattt tgactctgta ttggtacaga tgatagctat aggggagcag
    34021 acaggggaat tagagaatat aagtaaacag atggccgaat tctatgagta tgaatccgag
    34081 atttatttaa ataggatggc atcaatgata gagcctgttt taataattgc agttggtatt
    34141 atagttgcga tactggttgt atcaatattt atgccaatgc ttagtatata tgatgctatg
    34201 taggagggaa atgacaaatg aacaaggttt atgtatcata ttatggcgat tctatttcca
    34261 tagttgaggg cagatataaa cacaataagg ataagtttta tataaaaaat cttaatgtgt
    34321 tttcaataga ggatattgca caagattttt ctaaggaaaa gtatgctcta ttgagatacg
    34381 cattagaaaa tgttaagtta aaatcaagac atgtagtttt ttgtttaaat acaagagatg
    34441 taattttaaa accccaaaaa cttcctaata tggataaaaa ggatttagac ggatttatga
    34501 agctagagat ggacgaaatg atggctttgg agtcagatga atatgtattt tcgtatgaag
    34561 tatctagtga aacacctgat aattcagatg gcgatgaatc aagcttaaat cttatcattg
    34621 gagctataca aaaggaagag gtaaatgcaa ttgtagagat aatacatgaa tttgatttaa
    34681 tattagatag aatagataca ttatcaacag cttacttaag aatgcttaaa aatttagatt
    34741 acaatgatat aatggtaact aatataagtg acaatagcac aattataaat atatacaaga
    34801 aagatacttt atttattagt gataatatac ctataaagat aactgctaaa gatatggaca
    34861 tgcaattatt aaatgtagta gaagaatcaa aaggtcttat gaattactat tcgtcaagaa
    34921 actttggtaa ggttacagat actatattaa tattaggaaa aaggtattcc aataaattaa
    34981 tttatgaaac ttttagctct gcattttcaa gctatgtttc tcaaggtctt actgagataa
    35041 tggatatatc tgatatgata actggagata tagatgaaga tgatataaat tcaattgtag
    35101 agcttttagg aagtatgata gaacctaaag ggaaaagaga ttttgaaaat ataaactttt
    35161 taccaatgga tatacttaga aaacagctaa aagctaaaca gatgaaaaac atactgaaaa
    35221 ttgctccagt agttattttg attcttgcta taccttattt atgtttaatt ttttcaaata
    35281 atttagcaaa caaggaactt gaaaatgtta atgctgaaat aagaaatatt gaatctgcat
    35341 attatcagat tggaaatata gaaaaaatga tacagagtaa aagcgaagaa ataaaggtat
    35401 atgatatgtt aattggaaaa aaggtaaagt gggaaaattt gttggatgat atagataaaa
    35461 atactccaag taaagttgag ctaacaagtt tatcaacgac ttatcaaaat cttggagcta
    35521 ataataaagc tgataactca agcagtaata agactacaac agataaatca agtaacaatg
    35581 aaacaaaatc aaatacgaaa agtgatagta atggagataa aacaaataat gatttaaatg
    35641 aagataagac tacaaatgtg tcagaagcat taactggaaa tagtgagact aatagtaata
    35701 acacagataa agatgataaa actccattgt atgataagat accaaatgtt ataaacatag
    35761 aaggaaatgc taaagattcc tcttatgtag gtcaattttt atataaatta aagggattgt
    35821 attatttcaa ggatgttaaa ttacatagca taaaaagtaa tgcagaagat tctacctata
    35881 catttagtat gacattatac ctgaaagaag gtgtattaac taatgaataa agatatattt
    35941 aaaaaagata taaaagatat atttaaaatg gaagttagtc taaaaggggt tcttataaag
    36001 gttataattt tattatctat tttatcatat ggttactttg gactttaccc tcaatatcag
    36061 aaatatattg ttacaaaaaa ttctgtaaaa caagctactg aaaaattaaa tatatataaa
    36121 gagaaaactg cacttatgcc aaaatatgaa aaacaacttg aagaagttga aagtgagtta
    36181 aaagaaaaaa gcaaaaatct tttatatgat atgcaagatg gtcttttttt aataggttta
    36241 gataaaaaaa tgaaggctta taatattgac ttaactagtt atgacgttgg aaatgttaga
    36301 gaatacgaac atttttatgg tgtatcaaca acaataagtg ttagaggtga ttatagaaat
    36361 gtcaaaaaat taatggctta tttagaagaa caaaaaaatg ttactcaaat actagattat
    36421 acaatgactt catatataga accagaaaaa gaagaggaag aaacaacaaa caataaggat
    36481 ttaattaaaa atgtgaacat aaataaagat acaaaaatat actgggtgga aggcgaaaat
    36541 aagtggcatt tatataagga ttgtccattg ataaaagagg gagagattct aaaaaatgac
    36601 aaacttttag ataggtctac tagttatcta tgtaatactt gtgtacttag agctgcaaca
    36661 gaaaaagaag caaaaaaaga agtcgtagct ccaaaggcag aaggtgtagt agatgctaca
    36721 tttaaattta taatgtacac taaagagaat actacaatga tacttgatac agataatcca
    36781 tcttcatgga gaccgggaaa atataatcca tttaagtcta gtgcgaaata aagctaagta
    36841 agctttaaag ataggtgatg agtttgtaca aaaataatga aaaaggtctt accttattag
    36901 aagtaataat agctgttttt atactgacaa tagttttaag catttcttat aaggtgttta
    36961 atggtataac atcagcagta aaaaagcaac agattattac agatgctcaa gtaaatatta
    37021 acctaattaa taagtatcta aatagagatt tggaaaactg taaagagcta actaaaactg
    37081 gttcaggtag taattatgaa tataatatag agacgccaga taatattgta aaatatgaag
    37141 tttccataga aactaaaaaa aatacagagg tatattctgt aacaagaatc gaaaaaaata
    37201 caattgatac agaaaatgaa gttagagaag agataatcta taatcaacca ctagttcaaa
    37261 acaataaaga aatgaaagaa acaccattta aaatagaaaa gcaaactgat aaatctattt
    37321 atactgtaag tatattctat aatgaatcag ttcaagaagg tcataaaaat agcaatttaa
    37381 ataacaagac ttatacattt gatgttatgt cgagaatagg ataataagaa tttattaaaa
    37441 ataagtaggt tgataaaata tgagtaaaaa gaatagtaaa agaggatttt ccttaattga
    37501 agtgttagta gctatggcta ttatgggaat tatactattt gcgtttttta atattatcaa
    37561 tactaataat aaagcaaata ttaaaaatga cacagatata aattccttaa actatgtcca
    37621 aagtgaaata gaaaatctaa gagagaagat aaaaagtgga gaatttgatt ttgatagttt
    37681 agataaaatg gaagatggga ctgtcgtata tgaaaaatta atagataagt caaaaaaaat
    37741 tgtgtatgat aaagttctta gtgagggtaa cgtgagctta tatgatactc catatgaaaa
    37801 gattacaaca ataaaagatg aagatggtaa tttaatcgat aaagaaaata ttacaaataa
    37861 gataaagact attgtagaag ataaaagtgg tcagatatat aaaatagctg taactgggaa
    37921 aagcatgaat gactattcaa gtaaaaaaga agttaagatt gtaactgaaa tatttaaaga
    37981 taaataattt tacttggggg tgagattttg aggaagtgga ataaatttaa aagtgaaaga
    38041 ggggcagctt tagttttagt tctggttgta gtagcattac tttctattgt tggattgatg
    38101 ttttcaaatc agatagccaa tagaataaaa tctacaaaga ctactaatga gggtatacaa
    38161 gcaaagtatt tagcagagac atgtgtggaa aatagtattg ataaagcata tgaaaaattg
    38221 tatgatgagc ttgagaaaat ggataatgag tttaaaagtg aaaatcaaca aaaatccata
    38281 tctaggtcaa aattaagaaa tatatcagat gaagatttta ataatcaaaa tgaagaaaat
    38341 cttgaagtag aaagactagg atatatgaat aatataaatt tctatttaaa caaagcttcc
    38401 tcagatttgg aaaaagctag tatagaattg aaaaaattat atgatttaga tatgttggat
    38461 tacagagaca ttgaatatgt agatgaaaat attatttcac atagaaattc tattttagat
    38521 atttgtaaga attatacttc tggagatatt agtaaaataa atgaatatat tctggatgaa
    38581 gatataaatt caactacgtt agttgaagca aagttagtaa ataatgatat tcttttaaaa
    38641 atgtttttag aagaaaataa aattgaaaat gaacatttaa attcagcgtt ttcatacact
    38701 tataaggcat tagataaaat ttctttggcg atgcaaaata tgattgagta taggcataca
    38761 tttcatatag atgagcaaaa agtagaagta tctaatggga ttccaaattc tcaacaatat
    38821 tatgaattaa tacaaaatcc tataataaat agtaaagagt atagctggaa tagtaaatgg
    38881 gatacattag aaaatctatt ggaaacttta ccaaatcaaa ctcaaggttt taattcttta
    38941 agagttcatt tgagaaataa tgtaagaaaa tttgaggagt taagcgataa tatatctagt
    39001 ggtaaaaaaa atacagcaaa aaatttctta aagtataaag agttattgta tgaaatatca
    39061 gaccaatgta atcaactaaa aagtatgtct tatgagaaaa tacctgttaa atatgataac
    39121 atggccttga taacaacttt tgactatata caaaatgagc ttttagcaga gataaaatgt
    39181 agattaaaag aattaaaacc tcaagaagtt gataaaacag aagatattac tataaaaata
    39241 cctttttata aggctgacta cgacatgaca aaagaaggat ggcctaaatt aaaagaaaat
    39301 ggttcagggg cggagttaag cttaatggta actggtgata aagatggaat aaaagaagtg
    39361 gaagttacag atagtaaaaa aaatattatt ggtttaggtg ttgaagaaaa ttcaaattca
    39421 aagtataaag ttgaagctat tataaatttt aatctaaata tagatacaaa tatagtcgga
    39481 aattatgata taaaagataa aattttgatt aatcatgaca taagttcata caaaaaagta
    39541 aactagatat aataagtaac ttagtgtgaa taaataataa aataatttta ttatttacta
    39601 ctaaaaaaat aagtaaacta aaaaaagata tggagattaa atattatgta tatttatgat
    39661 ttattagagc aaggtataag actaaacgca tcagatatac acataacagt tggaacgaat
    39721 cctgtagcta gagtaaaagg tggatttgta aaactaagtg aacagatatt gacaccagaa
    39781 gtaacaatgc aaatggcaaa agacatagca ggagaatcta tgtttaaagt aataaaagaa
    39841 catggagaag ctgatttttc agcttctcta aaaacagggg aaagatttag ggtaaatgca
    39901 tataggcaaa aaggaaatta cgcaatagca ataaggacta taacagcaga aattccaaca
    39961 tttgaaaaat taggtcttcc agaaaatata aaatctttta ctgaaaagca taaaggatta
    40021 gttttagtta caggtccaac aggaagtggt aaaagtacaa cacttgcaag tatgataaac
    40081 ataataaatg aaaaacaaca aaaacatata attacacttg aagacccgat agaatatgta
    40141 catcatcata aacaaagttt agtaaatcaa agagaagtag gaactgatac agaaagtttt
    40201 cattcagccc ttagagctat tttgcgtcag gacccagatg taatactaat aggagagatg
    40261 agagaccctg aaactgtttc aatagcatta acagcagcag aaacaggtca cttagtattt
    40321 tcaacactac atacagtagg ggcagctaag acaattgata gaatagtaga catgtttcaa
    40381 ccatcccaac agcaacaaat aaaaacacag ttatctacag tctgtgaagg tgtggtatca
    40441 cagcagttac ttcctacagc agatggaaaa ggcagaatag cagcaattga attgatgttt
    40501 gctactccag caataaaaaa tctgataagg gaaggcaaaa catatcaaat tccaaacatg
    40561 atacaaactg gagttaaatc aggtatgaaa actatggacc aagatttaat ggaactttat
    40621 aaaaatggaa agattacaaa agatatggca cttagtaggt gtactgacca agagtttatg
    40681 acaagaatga taggtggagt aaactataat ggatattata atcgttaatc tatatgtatt
    40741 tatagtgggt atagtgtttg gaagcttctt taacgtctgc atttttagga ttccagaagg
    40801 tatatctatt tctagacctc cctcccattg tatgagttgt aatactagac taaagccaat
    40861 agacttaata ccagtgctaa gctatttaat aagtggcaga aagtgtagat attgttatga
    40921 gaaaatttct agtagatatg ctatagtaga attaattaca ggaattttat ttttaatagt
    40981 atttatgtta tatggaatat ctacatcaac tgtttactat ttggtacttg tatctttact
    41041 gattataatt acatttatag atattgacca ctttataata ccagatgaaa tactgatttt
    41101 tggagctatt tttgctataa tttttaacct tttatttaaa gaaattccag ttaaggattc
    41161 aattataggt ttttttattt gtggaggaag tgtctggctt atagttcttt taattgaatt
    41221 tgtaataaaa aaagagtgta tgggtggagg agatattaaa ctatttgcaa tgctaggtct
    41281 ttacatgggt gttaaaaata gtcttttgac agctttacta agcgtctatg tgggagcagt
    41341 ctatggaatc tgtgtaataa ttataagtaa gacaaaagga aaggaatata attctattat
    41401 accatatggt ccttttatat ctgttggagc attaataaca attttatgtg gaaaacaatt
    41461 actcgaattt tatttttcta tgattacata gataatagtc aagctaaatc aagttttaat
    41521 ttaaaaaaat gaattaaagt attcaataag gacaatatta ttattaaccc tattactaaa
    41581 gtgctacaaa ctatggagta tataataata atttccttat tttttgcaca tttgataaat
    41641 aaatctctat gtgttttttg tgatagagaa aagaaaaact tatataatac gttttttatt
    41701 tacataataa ctgtagtttt atctgtatta atatatctaa aatttggaat tagtgtagaa
    41761 tgtgtacaat atatggtttt aattccattt ctaataatta tatccattgt agattactac
    41821 acaatatatg tatatgatat aacaatagtt agtggtataa tagttcaagg tataattttt
    41881 ttggtctttt gcaatatagt tcaatttgat tatataaatc atatatttgg actagtgata
    41941 ggctttatta taccttatat tattgctaaa ttaacaaaag gattaggcta tggagatgta
    42001 ggtctctata gcttatgttg ctttgcattg ggaaataatt atgggtttta tgtgatagtt
    42061 ttatcattta ttttagcgtt tttgtttttt attattttat acataactaa aatatttaaa
    42121 gatatagata taaaaaagca aattcctttt acacctttta tttccttagc aacaatttta
    42181 ataatgttta cagagtataa tatatttaat ttttattata gtttgttata caaatttata
    42241 taacaggagg taagaaatgt acgtagtagt agggttaggt aatccaggaa agaagtatga
    42301 gaagactaga cataacgttg gatttgatgt gatagatatt cttgctaaag aatacaatat
    42361 tagtgttact aaaataaaac ataaagcttt aattggtgaa gggagagtag gtactgaaaa
    42421 agtattatta gttaaaccac aaacttatat gaatctaagt ggagaaacat taatagatat
    42481 atataaatat tacaaggttg atttaagtaa tatagtagta gtatatgatg atatagattt
    42541 agaagttgga aagatacgta taagaaaaaa aggaagtggg ggaactcata atggcatgaa
    42601 atctataact aagtgcctag gttcaaatga ctttccaaga gtaagagtag gtgtatctaa
    42661 gccagaagtt ggtcaagact tagcagattt tgtactttct agatttagaa aagaagaatc
    42721 tgataacata aatgaagcat tagaaaaagc agcatatgct attgactcaa taataagaga
    42781 aaatatagat atgtctatga acaaatacaa tggatagtga gagggagatt taaatgaatg
    42841 atgttttttt atatcctttg caaaattcaa aagagtataa agatataata aattgtataa
    42901 aaaatacaaa aggttcatta ttggttaatg gacttttacc agtacaaaaa cctcatatat
    42961 cttattctat atttaatgat ttatcacgac aaatgatttt tataactagt agtgatttag
    43021 aagcaaagaa agtatatgaa gatttaagtt tttatattga agataaggtt gaatatttag
    43081 gttttcaaga tatttatttt tatcacttgg atgcaaagga cagaaatgaa gaagcaaaga
    43141 aattaaaggt attgttaaaa ctagcaaata aagaaaaaat aattttagta acttctattg
    43201 aggcagtttt aagaaaatat ataccaaaac aagttttgct cgatagtgta tctcattata
    43261 aggtgggaga taacttagac ttagaaaggt taactgaaaa attagtttca ttgggatatg
    43321 aaagagtttc aaaaatagag gggtttggtc aatttagtat aagaggtgga attattgatg
    43381 tattttcact tgaatataca aatccaattc gtatggaatt atttgatgat gagatagatt
    43441 ccatacgaac ttttgacgta tattcacaaa aatcaattga taaattgcaa caattctcta
    43501 taactccatc tagggaattt atttatccag aaaaaactac agatgcatta gttaaactaa
    43561 aaaaagaaac aactaaaaat actgatgaag gtacatttca aaatatagac tatatatcga
    43621 gtaagactta ttttgaaggt gtagaaaact atatagatta tatttatcca gaagaaaaca
    43681 aaagtatatt tacctatcta gcagatgatg caatagtatt tattaacgat ataacaagac
    43741 ttaaagaaag atgcgaaaac tatataaatg agtttagaga aaattataaa ctaaatcttg
    43801 aaagaggttt ggctattaaa aaccaaggta aattgttata tcactataca gatttagagt
    43861 acttagtaaa agacaagtct gtggtattaa actctctatt gccaaagtct ataaataatt
    43921 tttctataaa atctataata aattttgaaa gtagagaagt tcctaccttt aatggaaagg
    43981 tagatttgct tgtagaagaa ttaaatcggc tgaaatataa tggatacaaa ataattttag
    44041 caacaaatac cttagaaaga gcaaataaac taggaaaaga tttattggac aaaggcttag
    44101 aaacaaccat ttctaaagat agagatattg agattaaatc ttcacaagtt ataattgtac
    44161 ctgcacacat aaacagtggt tttcagtata aatctataaa gtttgttgtt ataacagata
    44221 atgaaatgat aggtgtttat aaaagagcat ctaaaactac caataaaaaa gttaaaaaag
    44281 gaaaaaaaat agaatcattt ttagatttaa gtgttggaga ctatgtagtg catgaaaata
    44341 gtggtgtagg tagatacaca ggaattgaac aaattacagt caatgctatt aaaaaagatt
    44401 atatgaaaat agtatatcaa ggtggagata atctatatgt acctatagac cagatggaca
    44461 aagtacaaaa atatattggt gcagaagtag aaaaagttaa gttaaataag cttggaacaa
    44521 atgagtggac aaaagcaaaa gcaaaagtta aaaaagaaat tgaagatatg acaaaagatt
    44581 tgattgagct ttatgcgaaa cgtgaaaaaa tacaaggtta taagttttca aaagacacac
    44641 cttggcaggc agaatttgaa tctttgtttc catatcaaga aacagaggac caattaaagg
    44701 cgatagaaga aactaaaaaa gatatggaat caagtaaggt aatggataga ctagtatgtg
    44761 gagacgttgg ttatggaaaa acagaagtag ctattagaag tatttttaaa gcttgtatgg
    44821 accaaaaaca agttgctgta ttggttccaa caacaatatt ggctcaacaa cattacaata
    44881 cattcaaaga gaggtttgaa aattatcctt tgagagtaga agttttaagt agatttaaaa
    44941 caccaaaaca acaaaaacag attattgaag atgctaaaaa aggattagta gatattttga
    45001 ttggaacaca tagaataata tccaaagata taaatttacc aaacttaggt cttgtagtca
    45061 ttgatgaaga gcaaagattt ggagtaaaac ataaagaagc tttaaagaaa attaaatcta
    45121 cagtagatgt acttacactt tcagcaactc ctataccaag aacattacat atgtctttaa
    45181 gtggaataag agacatgagt gttatagaag aacctccaca agaaagacat cctgtaataa
    45241 catatgttac agagagtaag gaaagcgtaa ttcaagatga gatagagaga gagttaagta
    45301 gaggtggaca ggtatttttt gtatacaata gagttgaaca tattgaagag atggcaagta
    45361 tgattcaaaa actcgtacca gatgctagag tggctgttgc acatggaaga atgacttcta
    45421 aatcattaga aaacataatc ctaggatttt taaataaaga ttatgatgta ctagtctgta
    45481 ctacaataat tgaaactggt atggatatat ccaatgcaaa tacaatgatt atatatgatg
    45541 cagataaaat gggcttggcg caactttacc aattgagagg tagggttgga agaagttcaa
    45601 gacaaggata tgcatatctt ttatatgaaa aagataaaac tctaagtgag atagcagaga
    45661 agagattaaa agctatcaga gaatttacag agtttggttc tggttttaaa atagcaatga
    45721 gagaccttga aataagaggc gctggaaata ttttaggttc tcaacaacat ggtcatatgg
    45781 cagttatagg ttatgatttg tatgttaaaa tgcttaatga tgcaatcaaa aaagttaaag
    45841 gagaacctat tgtagaggaa attgatgttg aaatagattt aagtgtaaat gcatacattc
    45901 cagataatta tatcaaagat gagttaatta aaattgaaat gtataagaaa atagcttcta
    45961 ttgaaaataa agaagacatg ttggatatac aagaagaact tgaggataga ttctctgata
    46021 tacctaaacc agtccagaca cttcttacaa tagcttatat aaaatcgtta tgtaagatat
    46081 tgaaaataga aaagataaga caattaaaag atgaaatatt attagttcca ataacaaagt
    46141 atagaactaa acagaaaata ggttataata tagttacaga attagaagaa ttattagaaa
    46201 aaatgtgcaa ggtaaaataa cttgtaaatt taagaaggga tgttttaaat ttgaaaaagg
    46261 taataacatt ggtaatagct atgattttgg tagtatctgt gactgcttgc aattctagta
    46321 aaggagaaac tgtggcaaca gttgaaggta caaagatatc atcagatgaa tttaaaaaaa
    46381 ctatagctct ttataaggat tctatggagc aaacttatgg aaaagatata tgggataagg
    46441 aagttgaaaa gggtgtaaaa tacaaggaca agtttaaaga tttaattctt gaccaactta
    46501 taactacaga agtaatatat tctcaagcta aaaaagataa cttacttcct aaaaaggagg
    46561 atgttgaaaa aagctttaaa gaattaaaag atgctatggg gaaagatgaa aaatataaag
    46621 aacagcttaa gaaattaggg atagatgatg agtttttaag agaccaacaa gagaaagatt
    46681 tagcaatgca aaactatcaa agtaacttta ctaaaaagac taaaatatca gatgaagaaa
    46741 tgaaaaaata ctatgataca cataaagatg aatttaaaaa agatgaggta gaagcttctc
    46801 atattttatt gaaaacagta gatgacaata acaagccact ttcagctaag gaaaaagctg
    46861 aagctaagaa aaaagctgag gaggctctta aagaagttaa atcaggtgag gactttgcaa
    46921 aagtagcaaa aaaatattca caagatgctt cagcaagtga tggtggtaaa ttaggattct
    46981 tttcaagggg gcaaatggtt gctgaatttg aagacgctgc attttctatg aaaaagggtg
    47041 aagtatctga tttagttgaa actcaatatg gataccacat aattaaagta acagacagaa
    47101 taaatgagca aacatcattt gaagatgcta aagaaactat aaaagaccaa ctattaaaaa
    47161 ataaatatca agagcaaata gaaaaattaa ctaaagaagc taaagtagaa aaagatgaaa
    47221 aagtaataaa taaaatcaca atctaagacc taaaaaagag taatatgctt aaaaaagcta
    47281 tatctggata agatatagct ttttttgtat atttttctta acaatggtaa aaataaactt
    47341 aaagtaattt atggagggat taaaaaatat gaaagcaaca ggtatagtta gaagaataga
    47401 tgatcttgga agggtagtta tcccaaaaga gataagaaag acattaagaa ttagagaagg
    47461 agacccttta gagatattca cagcaaaaga tggagaagtc atacttaaaa aatactctcc
    47521 aataggtgaa ttaaatgaat tttcgcaaga atatgctgaa acattagctg aagtactagg
    47581 atatggagtg ttgataacag acttagattc tataatagct gtgtctaagc ttcctaaaaa
    47641 agattataaa gaaaaaagta taagtgatga gttagaagca ataataagtg aaagaacagt
    47701 aaagtattca aaagataaaa acattttacc attattcaaa gaagaccaaa aagaatatac
    47761 tagtcaagtt atcatgccta taattagtgc atctggtgac tgtataggtt caattgtagt
    47821 tgtttcaaag gacaaagata caattgcaga aagtgaagaa aaatctttaa aaattgctgc
    47881 taacttttta ggaaaacaag ttcaataatt ttatcataaa gaccttttac atgaaggtct
    47941 tttgaagttt ttgtgtaaaa tattgaacat agcattaaaa atatgttata ttaaagtttg
    48001 ttatataaac agtgtggagg ttatgttatg aacaataaca aaaataaaga ctcctttcta
    48061 aaaggagccc ttatacttgg gctagcaggt gtaatcgtaa aaataatggg tggatttttt
    48121 aggattcccc ttggaaacat gattggttca gaagggatgg gatactatca ggctgcttat
    48181 cctgtgtata ctctattttt aacattagct actgctggat ttccaacagc tgtggctaag
    48241 ttggtttcgg aaaaagttgc cattggaaat tttaaaggtg caaataagat atttaaggta
    48301 tcacatacag ttttatttat tactggtata atatcatttt gtatattatt ttttggagcc
    48361 gactacatag taacaaacat aatgaaaaat ccaggtgcgt tatactctat gaaagctatt
    48421 gctccagcat tactatttgt tccagcaatg tctgcatata gaggttattt tcaagggaga
    48481 caagatatga ctaaaattgc tgtgtctcaa gttgcagagc aattttttag agttgtatta
    48541 ggtcttactt tggcttactt gcttatgaag agtctaggtc agacttttgg tgcagcggga
    48601 gctatatcag gagctacaat aggttcaata gcatctatgc tttacttaat gtttgcttat
    48661 atgctaggga gaaaagagcg tagagcagag atagatgcaa gccaaagatt taaagatgag
    48721 agagtgtctt atatttttaa aaagctttta actgttgcca ttcctataac aataggagca
    48781 tcagtaatgc cacttgtaaa tatgatagat aatgttattg taataagaag acttatggaa
    48841 gcaggcttta catacaaagt ggcaaattca atgtttggtc aattaacagg tatggcaatg
    48901 gccacaataa atttaccagc agtcataaca actgcaatga gtatgagctt agttccagct
    48961 atttctaaag catatgcatt aggaaataag tcaaaagcta gaaaagatac taagagtgca
    49021 gttaaggtaa ctttacttat agtattgcct tgtgcgtttg gtatggcttc tttagcaata
    49081 ccaataatgg ggcttttatt tccacatgaa ccatcttctg taggaactat tttgtttact
    49141 cttactccat gtgtattatt tttaggatta atacagacat tgactggtat aattcaagga
    49201 atgggaaaac caatagtacc tgtaattgct ttatgtgttg gtatgctatg taaaattgta
    49261 ataagttata ctttaacagg tatcccagat attaatgtac tgggttcagc ctttggtaca
    49321 gttacagcgt actttgtggc agccatgatt aacttactat atgttaaaaa acacatgaat
    49381 gtaaactttt ctaaaaaaga atttataata aagccattta taacagttat gacaatgttt
    49441 ataatggtta agttgagtta tggtgcttta gttggattct taggaaacag catatccaca
    49501 ataattgcaa tatgtatcgg tggaattgta tatgtagtag taatacttgg aataggtgga
    49561 attaaaaaag aagagattct aactatgcca aaaggtgata aattatataa attgttaaaa
    49621 aaagttaaac ttataagata atataggaat atatatgcaa ataagggaaa tactatacaa
    49681 atagtaaatc tccttatttg tatagtaata taaaaataat gtgaaatttg ctaataggag
    49741 tgatgttatg ggtaagataa gtattgtagg tcttggacca ggagactatt ctcttataag
    49801 ccaaggtgtg ttagaatctt taaaaaatag ccctaaagtt ttttttagaa cagagaaaca
    49861 tccaataatt gataaactta aagaaactat acaatacact tctttagact acttttatga
    49921 aaaagaggaa aactttgaca atgtttattt gaaaatatct gaatttatca tagaagaatc
    49981 tgcaaagggt gatttagtat atgctgttcc tggtcatcca agagtcgcag aaaagactgt
    50041 aagtataata gagagattgg ccaatgaaaa gcacatagca gtagaaatag tgccttctat
    50101 gagctttgta gacgctatgt ttaactattt ggctatagac ccatctgagg gatttaaact
    50161 ggtagatgct tttgaaatag ataattcata tatagacttg gatacaagta tgataataac
    50221 tcaggtatat gataaattta tagcatctaa tgtaaaatta aaacttatgg aatattatga
    50281 ctataatcaa gaagtatgta tagtaaatgg agcaggtgtc aaagatttag aaaataaaaa
    50341 gtttataaag ctttgtgaat tagacagaaa tgaaaacttt tttgactatt taactagctt
    50401 atatataccc aaaagttcta aaaagatgta taatacagta catgacttag aaataatagt
    50461 taatacactt agaagcccat ctggatgtga atgggataaa aaacaaacac atcaatcatt
    50521 aaaaaattct gttatagagg aagcatatga actttgtaat gcaattgata ataatgatat
    50581 agatgaaatg gtagaagagt taggagatgt tcttttacag gttatattcc attgtcagat
    50641 aggaaatgag gagggctact ttgatttaaa agaagtagta aatggaatat gtaaaaaatt
    50701 aattcataga catcctcata tatttagtgg tgcaaaacta gatatgtcta agtttgaaaa
    50761 aacttgggaa gaattaaaga aagaagagaa aggcgaaagt actataacag atggccttag
    50821 aaggatacca aaacatttac cagctcttat gaaggctagt aaagttcaac ataaagcagc
    50881 acttgtcggc tttgattggg acaatgtaga agatgtattt aaaaaaattg aagaagaata
    50941 tcaggaatta cttgacgaac acagggtcgg gaatataaaa tacataaagg aagagctagg
    51001 cgatttatta ttttcgatag taaatctagc tagattttta gacatagact caggagaagc
    51061 cttgaactgt actacagaaa aattcataaa tagatttgag tttatagaaa aaagtgcaat
    51121 gaacttgaat aaaaaattag aagacatgac acttgaagag atggatgagt tttggaatca
    51181 ggctaaaaaa caataaaatt gtggaaggaa atttgtcaaa aatctagaac ttttatcaca
    51241 aagatagaag tctatattat aaacattttt aggaggtaaa tatcgtgaat aaagctgaat
    51301 tagtatcaaa gatggcagaa aaaagtggat taacaaagaa ggaagcagaa gctgcgttaa
    51361 acgcatttat gagttctgtt caagatgcac tagtaaataa tgaaaaagtt caattagttg
    51421 gatttggaac atttgagaca agagaaagag ctgctagaca aggaagaaat ccaagagatc
    51481 cagagcaagt tatagatata ccagcttcta aagcaccagt tttcaaagct ggaaaaggat
    51541 taaaggatat aataaatgga taattacaaa tcttgtgaaa aagtgtggat aaatttgcca
    51601 cactttttct atagagccaa ggaaggtgat aattatgaga ttagataaat ttttaaaagt
    51661 atctaggatt ataaaaagaa gaactgttgc taaagatgca tgtgataaag ggattgtcac
    51721 tataaatgga aaagttgcta aatcttcttc agaagtgaat attggagaca cattagaaat
    51781 acaatttgga gagaagaaga tgaagtttaa gataaatgaa gtaaaagagc atgtattaaa
    51841 aaatgatgca aaagaaatgt acgaaatttt agaataaaat taatagtcct ctagtatatt
    51901 aatagtagta ttattgaaat atttactggg gggatattat ggaacagaac ataactttga
    51961 aagatagatc aaagctggtt atttcgggag ttgagcacat atactctttt aatgacaaaa
    52021 gagtagagct caaaacttct gtaggcgaga tggtaattga aggcgaaaac ctagatatga
    52081 gcaagttaag tatagacgaa aatataatta gcatagatgg aactataaat tctatggtat
    52141 atgcaaagcc taaaaagcca caagagagtt tcttgaaaaa ggtatttaga tagatgatac
    52201 cttttactca agatgtaagc attttttatg ctactattta tggtggaata cttatagggg
    52261 tgttgtttga tttttataga gggctaagag gaaattttaa attcatcaat tattttgcaa
    52321 taatatttga tgtattgttt tggtttctag ctacagttat aatattcgta acaataaacc
    52381 ttacagaatt ttttgattta agatattatc attttgtggc tttgtttatt ggttttattt
    52441 tatactataa caccataagt aaaattgttt tatcaattat caataaaata attcgttttg
    52501 tgagaaattc ttttaaaaaa gttacacatt acatagtcag ttttttaaac aatttgtatt
    52561 acgttataat ctattcacta cacctactat ttgatattat attttatata ccaaacatat
    52621 ttatagcaac aagaaaaagt ataaaaagaa aatcaaataa aaaatcaaag aacaagaaaa
    52681 aatcaaaacc taagaagaaa aaaaataaaa ctaaaaaaag ggtgtaggaa aaatgaactt
    52741 aagaaaaaaa ttttcaggac agattattgt tatcagttta tttttaggaa tatcaatttt
    52801 tagtatgatg acaggatttg tatttgagta tacaaaagct aaggaatata aaaaagaaat
    52861 agcaagtcta aataaacaat taaaaaagac tgaaatacaa ataaacgcct taaagaaaga
    52921 tgaaaaatca tatgaaggag acttagagga tatagcaaga aaaagattaa atatggtaaa
    52981 accaaatgaa acagtttatg tagatataaa tcgttgatta aaacttgcta ataagtttac
    53041 agatgtattg attttaaaat ttaagattta ataaaaaagt cattcagtta aggatggctt
    53101 tttgttttta ttgaggagga gattttataa tgaaagtagg agctatagat attgggacaa
    53161 actcaatgag attattgata gcagattata gagatggaaa tttcataaac agaaaaaaat
    53221 ttgttaatac aactagaatt ggttatggtg tggatagtaa aggatatata aaggaagatg
    53281 ctattaaaag aaatataaaa gcactaaaag aattttctaa taagtgtaat gatgaaaagt
    53341 gtgaaaaaat ttattgtatg gggacatctg ctcttagaga cagtaaaaat ggagattatt
    53401 ttgttaaact agctaaagaa gaaactggaa tagatgttga tatagttaca ggaatagaag
    53461 aatcaaattt gggatttaag ggcgttttag aaggaataca agatgatgat actattattg
    53521 ttatagatat tggaggaggt tcaacagaat ttattgtagg tgactcagaa ggaattaaat
    53581 ttaataaaag tgaaaatgta ggtgctctta ggatgacaga gagatttttg aagcatgata
    53641 ttattgaaga tgaagagctt gaagctatga gttcatttat atatgatgag attgacaaaa
    53701 cgttaaatca tataaaatac agaggattaa aaactcttat aggtataggt ggtacgatta
    53761 catcattatc agcaatgaat caagaattag aggtttactc tatggaaaaa atacataata
    53821 gtaaaataca caaaaaagaa atagaagaaa ttctacaaaa attaataaag atgacattaa
    53881 gtgataaaaa gaacttaaaa gggctacaag aaaaacgtgc ggatattata actgctggtg
    53941 taaaaatatt gaatataata atggaaaaat tagaaataga agaaataacc gtaagtgaat
    54001 acgataattt ggaaggctta atatgtcaaa agtcaaaaaa aatgtattaa tattttttga
    54061 tttttaaaac cgattatgac aaaaaaaatt actcctcttt gttacaattc ttaatataaa
    54121 caaaagagga ggttttttta tgcaaagaag tgtagcagtt gtgaagaata agactgtaaa
    54181 accaaatgtc ataaaattaa taagcggata tattgatttt actacggcgg cattcgctgt
    54241 gatgggattt ttacttagta ggtctattat agtagactct gtagctccct taggaattgc
    54301 cttttttata tgtgcatcaa agattgataa gtacaaaata cctgtattca tatcaacatt
    54361 attaggaata ttgttatcat ctaatgattt tggaaatgta gcaaaatatg ctgtgtgcct
    54421 tacaatattt atggctatga ataaaaaatt aaaattatca gattcaattg ctaaggttgc
    54481 atttataggt gcaataatac tacttccaat ctccatagga caagctttct tttcaaatag
    54541 gtatgtgtat ggtcttctta ttgcaggagt agaagcaata ataatgttta tatctatata
    54601 tgtgttttct tatggaatag gtttaatggc caatgtcaac aataggatgt ctgtacggac
    54661 agaagaagct atatcaataa gtttactgct aacctttagc ataatgggaa taggagatat
    54721 atccctgttt ggaatatcaa taaggaccat tttatcgact gtattgatat tactgacctc
    54781 gatagtaggt ggagctacca tgggagcatc tagtggtgta attattggtg tagcatccat
    54841 tttaaataat atgacatcag ctatttatat gggaatatat tctttttcag ggttaataag
    54901 tggagcattt aataagataa ataaatattt ctgtatacta ggatatattc taagttggac
    54961 aataatatac ctatatactt ctggtattac ttctaatatg atgcaattaa gagatatact
    55021 attaggttgt ttgatagtat tggtattgcc agagagattg tttaataaga ttgaaaaatt
    55081 aataaaaagt aatgtagcct caaatgaaat cgtatacgat tatattatga gaagcaagaa
    55141 tttgactaat agtcgattga acagtattta taaaacttat gacgaccttg cagatacgtt
    55201 tgataagata agagaaaaag acaaagtatt agaccagaga gatatagcta acgtaataga
    55261 tatgattcat aatgatgaat gtaaaagttg tagtatgaga agaatgtgct gggaatcaag
    55321 atttaatcat acatacacta tgatatataa cattcttgaa aaaattgagg agaaagggga
    55381 gttaagtcta aacgatatac ctaaaaattt tagaaaggaa tgtatgaaac cagagtcaat
    55441 agtgaaaata tcaaatcact attacaaaat gtttgtatta gattatgatt ggagtgtgaa
    55501 gttctcagaa agtagaaagt taatagcaaa tcagataaga agtatttcaa aatcaattaa
    55561 atcgttatct caagatttag aaggtgacat aatgctagat atagaaaagg aaaaaaatat
    55621 atatgaacag ctagaaagat atgatataac agttgataaa gtaagttact taacaaaaag
    55681 taacagtgag tttgaaatat caatagaaaa gaaaacttgc catgatggat gtatgtgtga
    55741 agataaaatc gtaaatataa tttcagactt agtaggagaa aatatgtctg ttagaaaaat
    55801 agggtgtcac tgtttaggag gtaaatgtaa ggcaacattc gttaaatctc aaaaatataa
    55861 ggctgttaca gaagtttcag caatgtcaag ggatggacat attctttgtg gagacaatta
    55921 cacatacatg gagataaatg atggtaaata tatgatggct ataagtgatg gtatgggaaa
    55981 aggtaaaaaa gcatatgaag aatcttctgc cactattgat atactggaaa aaatgataga
    56041 tgcaaaaatt aaagacgaaa tagttattga tactataaat aatatgttgc tattaaagtc
    56101 ttcagaagag atgttttcaa ctttggattt gggaatttta gatttaaaac gaggttgttt
    56161 agaaactata aagatgggag cgtgttctac ttatataaaa agagaggatg gagaagttga
    56221 cttaatatca tcatcatcat tacctgtagg tatattatca gatgtaaaaa ttgatagaaa
    56281 aaatgtaaaa gttaaggaag gagactatgt aataatggtt tctgatggaa ttgtagatgc
    56341 aggaagaaat aacaatttag gagataattg gttaatatac ttcttaaaga atatagagac
    56401 tacaaatcca aaagaaattt caaatttaat attggataga gcattagagt tacaagcgtt
    56461 acaaatcgaa gatgacatga ctgttttagt tacgaaaata tgtacaaaat aaggtttgca
    56521 aaattatgtg tataagatgt ggataacttg tgtataatat gttaatagac ttttgaaaaa
    56581 agtatagtta ttaacaaaaa taacatataa atcaacaaaa tttgttgata agtatggcag
    56641 aaatgttaat aaaatgtaaa aaaagaaaaa acaaaagcta ttatcaaaag agattcatgt
    56701 tgaaataact aaatttctat gtaaagaaaa cctgtgaata tgttgattat tatgtggata
    56761 actattaatt cgatatttat ttatatagta tgaataattg aataatatat ctaaaaaaag
    56821 ccatcctatt attaagtaaa cttattgaaa ggatggcttt ttatgaatag aaaattgtgc
    56881 aaagcaataa tacctttatt tatttctatt ttttgcatgt taataataag tataaaagct
    56941 gaccaaggat atcaaaagaa tggtgacaga gcaattactg tcatgaataa caatgatact
    57001 gaagatgatg ctgaaaaaaa acaagaaata gactatgaaa aaacatgttg gaacttgcaa
    57061 tctttgttta aaagtgatga acagtggaaa aaagaactta agagttttga taaagatact
    57121 aaagagttga aaaattacat aggcaaagta acaaaatcgc caacacattt gtcttttgcc
    57181 ttaaacatta aggaaaaact tgatataaga ctaaataaac tttctgccta tgtaaaatta
    57241 aagcaagata ctaataaaaa ttcatataag tacttagata tgagtgatag catgagtaaa
    57301 tcctatggga attatatggg gatttgctca gatttagaat tagaaatact aaaattatca
    57361 aacaaagatt acaagaaaat tatttcaaat aaaaatataa atagaaaata tggtgcatat
    57421 ttaagagata taagaagaaa taaagtacat tatttggatg ataaatcaga agatattcta
    57481 agcaaagtat cttcaataag tagtcttcca agccaagtat atgaattatt tagaaatatg
    57541 gatagaaaaa ctaatttgac accagctcaa tatgcaagtg aattagagtc atcagataga
    57601 gaaaatagaa aaaaagctta tcaagatgaa cttataactt acaatgataa tataaataca
    57661 attgcaggtt taattactgg tcaagttaaa aagaatattt tttattctca ggaaagaggt
    57721 tatgagtctt ctttagaaat gtacttagaa tctgataatg tagatgaaaa agtatacaat
    57781 aatttgataa ggactgtaaa tggtaatatg gacagtctac acaaatatat agatttaaga
    57841 aaaaaagtat taaaattaga taaggttcat tcatatgata tgtttgtgcc tatggttaag
    57901 gctgttgata ataatattaa ttatgaaaag gcacaaagta tagtatattc agcgttgtca
    57961 cctttaggaa aagaatacaa tgatgtagta tataaagctt tcaatgaaaa atggatagat
    58021 gtttattcac atgaaaataa agtaagtggt ggatactgct tatctgttta tgaaaatcat
    58081 ccatatatac ttttaaatta taataattca ttaggctcag tttctacttt atcacatgag
    58141 cttggtcatg ctgtatacga atacttaagc tctaagaatc agaattattt taattcaaat
    58201 ccttctatat ttactcacga agttgcatct acaacgaatg aagcattact ttacgagatg
    58261 cttataaaag aggctaaagg caatgatgaa aaagcttatt atataacaca gtacttagac
    58321 ttgataaaag atactcttta tacacaaacc atgtatgctg aatttgaaaa aactatacat
    58381 gagttagtag aaaaaggaaa aagtgtaaac gcattagtat taaatgatgt ttggggacaa
    58441 cttcttaaaa aatattatgg acaaagctat gaattagacc aattatctaa ggtcggatgg
    58501 gctagaatcc cacattttta taatagtttc tatgtctata aatatgctac aggttgtagt
    58561 gcaggagtaa gttttgccca agacatacta aaaaatggtt ccgataacta tatgagcttt
    58621 ctcaaaaagg gaagttcaga ttatccaata aacttgttaa aatcaagtgg gataaattta
    58681 actaatacaa agccaataga aaatacaatc aaaaaatttg acagtttagt agcagaactt
    58741 gaaaagctat tataaacatt attataatcc acatggtaaa tatatcgaat taatgataaa
    58801 atatactaaa agtttaaagt cctatcaaga taggactttt tatttattaa ttagtgggag
    58861 atgattctat gcaagttaaa gttaaaaagg ctgtaatacc agcagcaggt ttaggaacta
    58921 gatttttgcc agctacaaag gcacaaccaa aagagatgtt gccaatagtt gataagccaa
    58981 ctctacaata cataatagaa gaagctgtgg cctcagggat agaggaaata ctaataataa
    59041 caggtagaaa taaaaagtct attgaagacc actttgataa atctgtagaa ttggaacttg
    59101 atttagagaa aaaaggtaaa aaagaattgt tagagatagt acaaaacata tctaacatga
    59161 ttaacataca ttatataaga caaaaagagc caaaaggatt aggagatgca atttattgtg
    59221 cgagacattt tataggtgat gagccatttg cagtaatgtt aggtgatgat attgtagata
    59281 atgatgtacc ttgcctaaaa caactaacag atgcatatga ggagtataga actacgatat
    59341 tgggtgttca aaaggtaaat caagaagata ctaataaata tggcataata gaagcaaaaa
    59401 atatagaagg tagagtttat aaggtaaaag acatggtgga aaagccagag tcaggaaaag
    59461 ctccttcaaa tattgctatt ttaggtagat atataataac tcctgaaatc tttgatattc
    59521 ttaaggattt accaccaggt aaaggtggag aggtacaact tacagatgct ttaaaaatat
    59581 tatctaagaa agaagctatg tatgcataca attttgaagg caagagatat gatgttggtg
    59641 acaagctagg atttttagaa gccactgttg actttgctct aaagaaagaa gaccttaagg
    59701 aagattttat aaaatatttg aaacatgtat gtagtgaatt tgataaaaat aacaatgtgt
    59761 tatacaataa tacagatgaa aaaatagatt taattgaagt caatgaaatc agagaacttg
    59821 aaattcaaaa ataattaatg aaaggtgatg tatggtggca aaatcaagtc agaaaagaat
    59881 taatagaata atagctgttg ggattgtggg aatccttgta ttaactagta taacagctgt
    59941 tttgagtatg attgcaacta tgtaataagg taaataacag aagttgatat acataaatat
    60001 aaaaaccata tataacttga tgtagttaaa aaattacaat attttagtta tatatggttt
    60061 ttataattta taaatgtaaa aaaaattttt tataatagtt gcatatttta aaagaaaata
    60121 ttattataag atataaatat agtgataaat ttataaaaac gtgctaagat tggacttgaa
    60181 atacagtaat atagtaggta ataatgtttt aaattttatt tattgaccat aatatataaa
    60241 taatgatatt attagactta actgtttaaa taaaactttt ctttttcatg ccttcaattt
    60301 tcaaaataag tatgtatata aatgaatata tagatgagga ggattttttt gattttagat
    60361 gataaagtat tagaaggatt aggtagtaag accttagttg agctacgaga gatagctaaa
    60421 gaattaaaaa taaaatcaat tactacatat aagaaaaatg agttaattga gattataaat
    60481 tccaaaagta aaaatgagga aaaaataaac gaagagacta aagaaaaaaa cgaagatatt
    60541 aaagaagaca taaaaaatag aaaagaaaat atagagcgtg aaagtataga aaaagaagtt
    60601 gaatataaga gccctaccaa atcatacaac aagaaagaaa tagataccca aaatatttcc
    60661 caaaaccaag aaaatagaaa tcaaagaaat gattataata agacaacaag tgtaaatgat
    60721 tgtaataagc catcaaatat atctaataga atggtcagaa ataataataa aaactattat
    60781 atgcctaaac aagttgatga atctaagata gtagatgaat ttaacacatc aaaagaggat
    60841 gaagtagtag gtgtacttga aattctgcca gatggatttg gttttttaag aggttcaaat
    60901 tatttgtcta ctgaaggaga tgtttatgtt tcaccatctc agataagaag atttaatatg
    60961 aaaacaggag ataagattaa gggaataact agacatccaa aaagtggaga gaaatttaga
    61021 gcgcttttat atgttcaaaa aataaatgat gaaaaccctg acacagctat acaaagaaat
    61081 gcgtttgaaa cattaacacc aatatttcca gaagaacgac ttacactgga aactaataga
    61141 aatgaaatag ctacaagaat tatagattta atttcaccta taggaaaagg acaaagaggg
    61201 ttgatagtag cacctccaaa agccgggaaa acagttcttt taaaaagcgt tgcaaatagt
    61261 atagctaaaa atcatccaaa tgttgaactt atagtactcc ttatagatga aagaccagag
    61321 gaagttactg acatgaaaga gtctattgaa ggagatgtta tatattctac ttttgaccaa
    61381 gtatcaagtc atcatgttaa ggttgctgag atggtattaa atagagctca aagattagtt
    61441 gaacatggca aagatgtagt aattttacta gatagtataa ctagattggc aagagcatat
    61501 aaccttacaa tatctcctac aggtagaact ttatctggag gtattgaccc tggtgcacta
    61561 catggaccta aaaagttttt tggtgcagca aggaatatta gacagggtgg ttctttgaca
    61621 atattaggaa cagcgttagt tgaaactggt tctaggatgg atgatgtaat atttgaggaa
    61681 tttaaaggta caggaaatat ggaattacat ttagatagaa aattagcaga aaaaagaata
    61741 ttccctgcaa tagatattta caagtctggt acaagaagag atgacttatt gcttgatgat
    61801 gaagaaaaga ctgctctttg gagattaaga agagaaatga gtaataattc agtaatggaa
    61861 attacagata aagtcattga acttataaag agaactaaag acaataaaga gtttgtaaaa
    61921 tcaataaaaa atttgtaaaa tcaataatac aaatgtaaat gtagattata taaagtaata
    61981 gaaaaatcac ttgaatggca taataagttg tgctataata atgtagttga taatgtaaaa
    62041 agaaagttaa tataattaat ttttttaaat aaagagaaga ggtgactata atgcaaaagg
    62101 aaatacaacc aaaatacaat ccagttgaag tgcgttgtgc ttgtgggaac acatttgttg
    62161 ctggttcaac taaggacgaa ataaaagttg aaatatgttc agagtgccat ccattctata
    62221 caggaaaaca aaagaacata gaaaaaggtg gaagaatcga caaattcaag aaaagattca
    62281 aaatggacta atttttataa aagtggagtt ggaggaagcc aactcctatt ttattacaaa
    62341 aaaacattca tattctactt taaattgtct ttttgtatta taataataaa tatgtaaaat
    62401 tgagtattct aaatacaata aaatgaggtg agtggatggc aaaacaagct gtaggtgggc
    62461 aagctgttat tgaaggtgta atgatgcagt caaaagacaa aagagcggta gctgttagaa
    62521 aaagtgacgg agaaatagca ctaaaagaag atagaataaa aagttgggta agagataaga
    62581 atatagataa gatacctttt gttagaggtt cttttgttat gatagataca atgattcaag
    62641 gcataaaaag cttaaacttt tcttcagagt tttttatgga agaagctgaa gaggataaat
    62701 ttgatttatt tataaagaaa atttttaaag ataaggcaaa tgatataatc ataatatttt
    62761 cattggttat agcaatgtta ctttctgctg gattattcat ttttatacct acattggtag
    62821 gaggcgcttt ttctaaagta atgcctaatg attttatgct taatttaata gaaggaatca
    62881 taaggatagc tatattattt gcatatatag tattgatttc acgaagtaag gatatagaaa
    62941 gagtctttca atatcatgga gcagaacata aatctatata ttgctatgaa aatgatttag
    63001 aacttacagt agagaatgct agaaaattta aaagattaca tcctagatgt ggtacaaatt
    63061 tcttatttat agttatggct gtatcaataa tattgtttgc attttttggt tggccaaatc
    63121 caatccttag aatatttatg agaattatat gtgtgcctat agtagcaggt ttatcttatg
    63181 aagtaattag agttcttggg aaatatgata atggatttac taaaattatt gcatatccag
    63241 gaatgatgtt gcaatatttt acaacaaaag agcctgatga tgagcaatta gaggttgctt
    63301 tggaagcatt aaaggcagta gtagattaaa gaaaaggata tttgttatga caataaaaga
    63361 tataattatt aaatattcag atatattaaa agatataagt gatactccaa gattggatac
    63421 agagttattg ttacaaaaaa cattgggtgt tgataggtta tatattcact taaatctaaa
    63481 taaagagcta actgaagagc aaaaaacaga atttataggt tttgcagaag aaagattaaa
    63541 tggaagacca atagcatata tagttgaaaa tagagagttt atgggattag atttttttgt
    63601 taaggaaggc gtattgattc caagaccaga tacagaaact ttagtagaag agataattga
    63661 aatatgtaga gaaaaaaaag atgtaagtat actagatata ggcactggtt ctggagctat
    63721 tacaataagt ttagcgaagt acattgaaaa ttctaaaatc atgtcttttg atatatcaga
    63781 gatagcctta gaaatagcta aaaaaaatgc tattacaaat gaagttgatg aaaaaataaa
    63841 atatattaat tctgatttat ttacagcaat aagtaatagt aacataaaat tcgatatcat
    63901 agtttcaaat ccaccatata ttaaaaaaca agatatagaa actctgcaca cacaggttaa
    63961 agattatgag ccatataatg ctcttgaagg tggagaagat ggattagact tttatagaag
    64021 aataacagaa caaggtaaga aatatttaaa taagtttgga atattagcat atgaagttgg
    64081 tcataatcaa gctgaagatg taataaatat tatgaaaagt aatggatata agaaaatata
    64141 tacaaagaag gatattcaag gcattgatag agttgttata ggttacaata tatgatataa
    64201 tcaacaattg atatgttaca tttaatcgag gtgaaagtat gttaaaaaaa ttagaggtat
    64261 tggaagatac atataaagac ttaagtgaaa aaataggtga tccggatgta ataaatgatc
    64321 aaaaagtttg gcaaaaatat ataaaagaac atgctgactt agaacctatt gttatgaaat
    64381 acagagagta taaaagtgtt ttagatagta taaaagaatc aaaagaaatt ttacaagaag
    64441 agtcagatga ggaattaaga gaattagcta aaatggagtt agctgagatg gaagaaaaag
    64501 tagcacctct ggaggaagaa ataaaaatac tattattgcc taaagaccct aatgatgata
    64561 agaacgttat agttgaaatt agaggtggag ctggaggaga tgaagcagct ctatttgcgg
    64621 gtgatttatt tagaatgtat tcaagatatg ctgaaagaag aagatggaaa atagaattat
    64681 tgagtgcaag tgatactgga gttggtggat ataaagaagt atcttttatg ataaaaggta
    64741 aaggtgcata ttcaagatta aagtatgaat ctggagttca tagagttcaa agaataccat
    64801 caactgaatc tggtggaaga atacacacat caacttctac tgttgcagta ttaccagaag
    64861 ttgaagatgt agaggttgaa ataaatccaa atgatttaag aatagacgtt ttccgttctt
    64921 caggtaatgg agggcaaagt gtcaatacta ctgactctgc tgttagggta acacatatac
    64981 ctacaggtga agtagtatct tgtcaggatg gaaaatcaca attaaaaaac aaagagcaag
    65041 ctttaaaaat attaaaagct agactttatg ataaagcatt ggcagaacaa cacaaagata
    65101 tagcagcaga aagaaaaagc caagtcggaa caggagacag gtcagaaaga ataagaacat
    65161 ataacttccc tcaaggtaga ataagtgacc atagaataaa tttaacttta tataagctag
    65221 atgcattctt agatggagat atagatgaaa tgatagatgc tttaattact gttgaccaaa
    65281 cagagaaaat gactgcaata taagtaatgt tttaaagaag ctgtttcttt ctagaaatta
    65341 ttttctattt tgaaacagct attttgcatt ttaggtcatg ttatcgtatt ctactgtata
    65401 taattgttat atacaagtat aggagggtta tatgatacta aaagtaacaa taattggact
    65461 tttggcaggt gttataggga caggattagg aggagtaata tcagctattt ttaaaagaga
    65521 ggttgataaa tatctaagtt tttttatggg aatatctggt ggaataatgt tggctgtagt
    65581 ggtgtttgat ttgatgaaag aatctatgga caaaatgggg ataatcaata cagttatatt
    65641 tacgtttgtt ggagctctca taactatgta cataaaaaca aaattagata tgtctggaaa
    65701 tatggcatcc ggatatctta tattcataag tatattacta cataatttac cagagggact
    65761 agctattggt tcttctttta tgtcaactga aagtttaggt attacacttg ctatagttat
    65821 aggtttacat aatataccag aagggttagc tatggcatta ggtttagtct gtaataaaat
    65881 gaaactaagt aaagttattt tatttactgt aatagctgga ttacctatgg gtctaggaag
    65941 ttttttaggt gtttattttg gaggagtatt tacttctctt ataggagtat ttcttgctac
    66001 agcaggaggt actatgatgt atgttgtatt ggaagaaatt tttccgcatt caaaaagtgt
    66061 gtattgtata attggtttct tgttaggtac aatgattgta aactatatat aaaattaaaa
    66121 tgaaagcagg catacaaaag atgaaaacta taataagtaa tattgatata aataatattg
    66181 attatgagga aataaaaata caagcaaaac ttcttagaga aggtaaaaca gttatttttc
    66241 caactgagac agtttatggg ctaggtgcaa atgcattaga tgaaaatgca gtaaagaaga
    66301 tttatgaagc gaaaggaaga cctagtgaca atccattaat agtccatata tatgaaaaag
    66361 aagaagtata tgatttagcc aaagatataa gtgataaagc taaacttgtt atagaaaagc
    66421 tttggccagg acctataaca attatattaa ataaaaaaga tataattcca tacaaaacta
    66481 gtggagggct tgatacagtt gcaataagga tgccttctaa tattattgcc agggcaataa
    66541 taaaagaagc tggtatacct attgcagctc cttctgcaaa tatctcaggt cgaccatctc
    66601 caacaaaagc aaaacatgta tatgaagaga tgaatggaag agtagatgga atagttttag
    66661 gaggagacag taattttgga ttggagtcaa ctgtattaga tttaacagaa gaaactccta
    66721 tgatactgag accaggaagt ataactaaag aagttttaga ggaacttctt ggagaagtaa
    66781 agcttgaccc atcattaagt aaaaaagaag ataatcaaaa agctaaagct cctggaatga
    66841 aatataaaca ttattctcca aatgcagatg tatatatcat atctggaaaa agagaaaatg
    66901 tagcaataaa gattaatgat atgataaaat ctaatagaga aaaaggtcta aagacaggtg
    66961 taatgtgtac tagtaaaaac cgagagtttt atgatggaga agtaatcgat ttaggaaact
    67021 ctcttgaaga agttgcaagt aatctgtttg atgctcttat agaaatggac aaaaagagtg
    67081 ttgatgtcat atattcagaa gagttcccta agactggagt tggacaagca attatgaata
    67141 gactacttaa gtcagcagga tacaaagtga taaaagctta aaagggagtt gtaaaatatg
    67201 aatatactta ttgtgtgtac aggtaatact tgtagaagcc ctatggctga ggccatatta
    67261 aagaaagcaa ttaaagaatc gggaagaagt gttgaagagt attctatatc atcagcaggt
    67321 atatctacag caaatggaat gagtgcttct gaaaattcta taaaagcact aaaggaaatc
    67381 ggtatagact tatcaaatca tagaagtaaa gtaattacca aaaaattaat tgatgaatca
    67441 gatataatac taacaatgac taaatctcat aaagaaattt tattacaagc agttccaaaa
    67501 tgcaaagaaa aagtgtatac ttttaaaggg tttgcaaata aaaatgagga agatatatct
    67561 gacccatttg gtggaaattt ggatagttat agaagcacta tgagagaaat agtgtattct
    67621 gtcaacgaaa tagtaaaaaa aatatgaaac ggaggataaa taaatgaaga taggattagg
    67681 ctgtgaccat ggaggatata atttaaaaaa agaaataata agctatttag aaggtaaagg
    67741 tatagaatgt gtagattatg gaactaataa tgcgacagat tctgttgatt atcctgttta
    67801 tggagaagta gttgcaaatt cggttataaa taaagacgta gattatggaa tattatgttg
    67861 tggtacagga ataggaatat ctttagctgc taataaggtt cctgggataa gatgtgcagt
    67921 tgtatcagat gtattttctg caaaaatgtc aaaagcacat aataatgcaa atatgttatc
    67981 attaggagaa agagttttag gaaaaggtct agcacttgag atagttgaag catggattaa
    68041 tacagatttt gaaggtgata gacatgctag aagagtaaat atgattaaat caatagaaga
    68101 aaaacataac aaataataaa aattacagtt ttatcaggag gaattatcaa aatgagcaaa
    68161 gtgatagaga caaaccatcc attaatacaa cataaattaa ctttaatgag agataaaaat
    68221 actggttcta aggattttag agagctttta actgaaattg caatgttaat ggggtatgaa
    68281 ataacaaaag atataccatt aaaagatgta gaaatagaaa ctcctattca aaaaacatca
    68341 tctaaagtag ttgcaggtaa aaaattagca ataattccaa ttttaagagc aggtcttggt
    68401 atggtagatg ggttagtaag tttaatgcca gcagcaaaag ttggacatgt aggactatat
    68461 agagacccag aaacattaaa accagttgaa tattactgta agcttcctca agacatagga
    68521 gaaagagata taatagtagt tgaccctatg cttgcaacag gaggttctgc tgtagcagct
    68581 atagatttac ttaagtctaa aggagctaaa agtataaaat tagctaactt agtagctgca
    68641 ccagaaggta tagcagaagt acaaaaatat catgatgatg ttgatatata tgttgcatca
    68701 gttgacgaaa gattaaatga acatggatat ataattcctg gtcttggtga tgctggagat
    68761 agattgtttg gaactaaata aaaataaata actataaata tttattaggg actttcttat
    68821 atagtgtata taattttatg taagaaggtt cctttttata tattttctca aaataggaat
    68881 tattgaattg ataaatttct cgaattgaga ataaaaagtt tttaccaatt aaaaaagatt
    68941 gcttatttta cagggtttta tagaatagta gtctatttta atgtggcatg ttagttgctt
    69001 acgattaagt gtatagatat taagcgtatt agttaaatta agtgttgaat attaataaat
    69061 attattggga gtggtaatac atgaagaatt gtatagtagt aagaggagct ggagatttag
    69121 caacagcagt tattcataaa ttacacaaca gtggttttaa agtagttgcg ttagaaatag
    69181 aagaaccatt agctataaga aggcaaattt ctttttgcga ggctgtttat gaaaaaaaag
    69241 taactgttga agatgtggaa tgcatatttt gcaatactga aaaagaaata gaagaagctt
    69301 tatctcaacg taaagtagcc ttgattatag acccaaaagg agaaaaatta tctaagttaa
    69361 atccaatcgt tttggttgat ggaatacttg ctaagaaaaa tttaggtacg actaaagata
    69421 tggcaccact tacaatagct ttaggtcctg ggttttgtgc aggcgaagat gtagatgttg
    69481 ttatagagac aatgagaggt cataatctag gaagaacaat aactaatggt agagcagaaa
    69541 aaaatacagg agtaccagga gcaataaaag gtttttctaa agagagagta atgcattcac
    69601 agcatgatgg tataatggaa aatgtatgta agataggtga tatagttgaa aagggagacc
    69661 tactttgcta tattaataat tatgaaaaaa aacatgaagt tagagcaaca atatctggag
    69721 ttcttagagg tttattaaaa gatggagcaa gggtcaacaa aaatttaaaa atattagaca
    69781 tagaccctag aaaagaagaa gttaagaatg cttttacaat atcagataaa gctagatgca
    69841 tagctggagg ggttttagaa gccatactaa acaatgggat ttatccccaa aattaattta
    69901 tactagataa agctattaat attttattaa gatgatataa taaatttaat agattaaaga
    69961 gagcatatga cgggtattta aaatttaaat ggtaaaaatg ctcttttttt attggacatt
    70021 caattaacat gtgtatataa tataaaaata agtatttatt taggttgaaa tctaataaat
    70081 acataatacc agtacataag taaagaggag aaaagtaaat tatgagacca tcatgggacg
    70141 aatacttcat ggaaattgca gaagtagtga aaaagcgttc aacttgtatt agaagacaag
    70201 taggagctgt tattgtaaga gataaacaaa tattaacaac tggatataat ggttctccaa
    70261 gaaatcttga acactgtgaa aatattggat gtaagaggca agagttaaat attccctcag
    70321 gagaaagaca tgaattatgc agagcattac atgctgaaca aaatgcgata atacaagctg
    70381 ctcataatgg cattagtgta gatggggcaa ctttgtatgt tactacaaga ccttgtgttt
    70441 tgtgtgcaaa aatgtgcata aatgcaggta tattaaaaat tgtctatgaa ggtgattatc
    70501 cagatgatat gtctacagaa ttattaaaag aagcaggaat agaactcata aaattttagt
    70561 agacaaaaat tatatgacaa taagtgccaa attgtgacac tggaatacaa tggtattaaa
    70621 tgattaaaag aaagtatttg aaaaatcatc agattagtag taagatatat tttataatta
    70681 aataaattta tgagatagat taattacatg ttatttattt tgtaataatg agggatacta
    70741 tttatgagta aaagaaatac acatacagaa attgcaaagt tgtttagttt aataagtcaa
    70801 ataggattga tgattgtaat atcaatatta ggatgtactt tcttaggaaa atttttggat
    70861 agtaaattga atactactcc agttctgaca ataatatttt tattgttggg tgttggaggt
    70921 gcttttagtg gtgtttataa aactctaata gtatatacac gaaggaagtg atatattgga
    70981 tataaaatta cttaaccagg taaggtcagt aacaaaaggt atagtaatat ttgatgtagt
    71041 tttaattgtg ttaatgttga taacatcaac attaagtaaa ccagtattat taggacttat
    71101 atttggctct ataatagcta tgttaaattt tagattatta gcgatatcac tggaaaagtc
    71161 agtgacattt cctgctggga aggcacaagc ttatgcatca gcacaatatg ctattagatt
    71221 atttataatg gcagttgttc tatttgcatc agctacggta ccacatttaa atataatcgg
    71281 aacagcattg ggattattga gcacaaagtt tgtcatatta tcaaaaaact ttataaataa
    71341 attaaagagg aaggaggcat aagtatgaat caagcgcatt attatctcat aggaaacttt
    71401 aagattagtg aaacaatact agtaagttgg ggaataatgg cctttttagc gatagcatct
    71461 tattttttga ctagaaactt aaaaaaagtt ccaactagta aagttcaaat attcttagaa
    71521 tttgcagtag gtggtcttgc taaaatggtt acagatgtta tggggaaaaa tacagtaaaa
    71581 agaatgccat atatgatacc atacatagga agcttgtttt tatttttcgc atgttcaaat
    71641 ttaagcccat tacttggatt aaggtcacca acaaccgact tagacacaac tgctgcatgg
    71701 gcaatgatta cattttttat gatttatttt gcaggagtta aatttaaggg gttatcatac
    71761 tttaaagaat tggctcaacc acttgccata atgttaccaa tcaatattat aggtgagtta
    71821 gctagaccaa tatcattaag tttccgtcca tttgggaata ttttaggtgg aacaataata
    71881 atgggtctgt tttatcaact tttaggtttt atatctagtt tgataccagg attatcaata
    71941 ccaattggac agatattaat accagtccca ttacacttgt actttgactt atttgcagga
    72001 ttgttacaag catatatatt cataatgtta acaatggtat ttatatcaag tgcaggagag
    72061 ttagattaag aaatcaactt atattaagat aaaaataaaa taatttaaaa aattaaagtt
    72121 ttaaggagga aataattatg gaaacagcaa tagtagcggc agcatcagca ataggagcag
    72181 ggatagcagt tgcaacaggt ataggtgcag gtataggtca aggtatagca gcagctaaag
    72241 ctgctgaagc agtaggaaac caaccagaag ctaaaggtga tataacatca actttattac
    72301 taggagttgc tatagcagag tcttcagcaa tatatggttt ggttatatca ataatacttc
    72361 tattcgtaaa tccattcttt aaatacttag gaatgtagat ttagtcctta aatattttga
    72421 gataggttta taggtaaatc atctcaaact tataatcatg agatgaactt tatcatctcg
    72481 tgattataag tagttatgat ttatggaaag gaggataatt atggagaaag cactagtagg
    72541 tataacgtgg gaatttgtat tccaaattgt taatactttt ataatatttt tacttctgag
    72601 aaagctttta ttcaagccag tattaaatat aattgaatca agagaaaatg atattaaaaa
    72661 tgatttggca gaaggcgaaa aagcaaaaaa tgaaggttta gctctgaaaa aagaatatga
    72721 gtcaaaaata aattttgcca aagatgaagg tcaagaaatc ataaaacaag caactataag
    72781 agcagagcag aaatcagatg atatagtaaa tactgcaaag aaagatgctc ttgatataaa
    72841 agaaaaagca aacaaagata tagaacaaga aaaacaaaag gttataaatg aaatcaaaaa
    72901 tgatatatct aacatagcac tacttgcagc atctaaagtt attgaaaaag atttagataa
    72961 atctaaacat gaagaattga tagaaaactt tataaaagag gtaggggaag ctaaatgata
    73021 aatgtaatag caaatagata tgccgaagcc ctatttcaat taggagaaga agaaaattca
    73081 actgatgttt tattcaaaga attagaaaaa gtagtagata tgatgactaa agttagtaaa
    73141 gatttctaca aagttttaaa atcaccatta gtttcaaaat cagaaaagaa aaacttggta
    73201 gaaattattt ttagtaaaga agtaagttct aacataaaaa actttttaaa agttttagta
    73261 gataaagaca gaatatcata tttagaagat atcgaattag cttataaaga attattaaat
    73321 aagaaaaata atgtaattgc tggtgtagca ataagtgcta ttccaatgag tgaaacagat
    73381 attaaagaac ttgaagtcaa actttcaaat aaatacaaca aaaatgttac tatagaaaat
    73441 gttgttgaca agactatact agggggagtt ctagttagaa ttggaaatga acaaatagat
    73501 ggcactgtga aaactcgtct tgataagatg aaagaaaagc tatctgaagt aatatcttaa
    73561 gaatggcggt gaacccatga acttaaaacc tgaagaaata agttctataa ttaaacagca
    73621 aataaaaaat tatgagaata aagttgagtt gacagataca ggtagtgttt taacagttgg
    73681 ggatggtata gcgagtgtat atggattaga aaaagctatg tctggtgagt tgctagagtt
    73741 cccaggtgaa atatatggta tggcacttaa cttggaagaa gaagtagttg gagctgttat
    73801 ccttggagat gacagtgaaa taaaagaagg cgatatagtt aagagaactg gaagaatagt
    73861 tgaagttcca gttggagaag ctttaatagg tagagttgta aactctttag gtcagccaat
    73921 agatggaaaa ggacctatag cgtacacaaa aactagacca gttgaatctg aggcacctgg
    73981 tataatagat agaaggtctg tttatgaacc attacaaaca ggaatcaaat caatagattc
    74041 aatgatacca attggtagag gtcaaagaga attaataata ggtgacagac aaactggtaa
    74101 aacatctata gttattgaca ctatactaaa tcaaaaagga aaagatgtta tctgtatata
    74161 tgtagcaatt gggcaaaaac gttctactat agctcaatta gttagttctt tagaaaaagg
    74221 tggggctcta gattatacaa tagtagtttc agcaacagca tctgaatcag caccacttca
    74281 atatatagca ccatatgctg gagcagctat gggtgaagaa tttatgtaca atggaaaaca
    74341 tgtacttata gtatatgatg atttaagtaa acaagccgtt gcatatagag aaatgtcatt
    74401 gttacttaga agaccaccag gacgtgaggc atatcctgga gatgtattct atttacattc
    74461 aagattactt gaaagagcag ctaagttatc tgatgaattg ggtggaggtt caatgactgc
    74521 cttgcctata atagagactc aagctggtga cgtttctgca tatataccaa caaatgttat
    74581 atctataaca gatggtcaaa tatacttaca accagagtta ttctattcag gtgtaagacc
    74641 agcagttgac cctggtatat cagtatcaag ggttggtggt tctgcgcaaa ttaaagcaat
    74701 gaaaaaagtt gcaggaacat taaaacttgc atattcacaa tatagagaac ttgcagcatt
    74761 ctcacaattt ggttctgact tagatgaaga tactaaaaag agacttgctc aaggtgaaag
    74821 aatcgttgaa atattaaaac aaggtgagca tcaaccaata aaagttgaaa atcaagttat
    74881 gataatatat gctgttataa ataatcatct agaggatatt ccgatagata atatagctag
    74941 atttgaatca gaattgtatg catttgtaga taataattat ccagaaatat caagaaaaat
    75001 attaggtgga gaagacttca ctcatgattt aacagatgca ataaatgaat ttaaagaaaa
    75061 gtttgttgtt gaagtataat cctttttaaa aaaggaggta aattaattgg caggagctgg
    75121 aatcaaagca atcaaaacac gtatgggaac tgttgaaagt acaaagcaaa taactaaagc
    75181 gatggaacta gttgcatctt ctaagcttag aaaagcaaaa gaaaaagctg aagattcaag
    75241 agaatatttt aatactttat acaatacagt aaaagatatt gcccaaacaa cacgtggaat
    75301 tagaaatgaa tttttaaaag aaagagaagt aaaaaataag tgctatgtag tagtagctgg
    75361 agacagagga cttgcaggtg ggtacaattc caatgtatta aaggagtctg tctctcatat
    75421 gaaaggcaaa aaggaaacag ttattactgt tggaaagaaa gcgcatgaat ttttttctaa
    75481 aagaaactac aatatagtga aagatataaa tagtgttgaa gcttgtggat atgaagatgc
    75541 gacagaaatt tcacaaacta ttattgacct gtataaaaaa ggtgaagtag atgaagttta
    75601 tattgcttat acaaaattta aatctgcttt atcacaagaa gttgaaattt taaaattgct
    75661 tccattagtc tttgaaaaag atacagacga acaaggaatg gaagtaaaag aagagaaaca
    75721 aaatagatca aaagtacaat atataccatc agcagaagca gttttaagtt atattgtacc
    75781 tcagtttata tcaggtacag tatatggtgg aattttggaa tcttttgcat cagagcaagg
    75841 tgctagaaga actgcgatgg aatcagccac agacaatgcg aatgaaatgc tatctaattt
    75901 agagttaagt tataacagag caagacagtc agctgtaact caagaaataa cagagatagt
    75961 tggtggagtt gaagctctaa aatagggagg ttaggaaatg gcaaatgtag gtaaagtagt
    76021 acagattgta ggagctgtac tagatgttaa gtttgatagt gaacaaagcc tacctaactt
    76081 attaaatgcg ttagtaataa agttaggaga taaagaaata gttgcagaag ttgctcaaca
    76141 tataggtgat gatactgtaa gatgtatagc tatgagtgca acagatggac ttgtaagagg
    76201 tatggaagtt gtagatacag gaggaccaat aagtgttcct gttggagatg agactttagg
    76261 tagaatattc aatgttcttg gaaaaccagt tgatgggaaa ccagctccaa aatctgcacc
    76321 taaattacct atacatagac cagcaccggc gtatgatgaa ctagaaacta cagcagagat
    76381 actagaaact ggtattaagg tagttgactt actagctcca tatctaaaag gtggaaaaat
    76441 aggtctattt ggaggagcag gagtaggaaa gacagtttta atacaagagc ttataaacaa
    76501 tattgctaag caacatggtg gtatttctgt attttcagga gtaggagaaa gaacaagaga
    76561 aggtaacgac ctttatggcg aaatgagtga gtctggagtt ataaataaaa cagctctagt
    76621 atttggccaa atgaatgaac cacctggagc gagaatgaga gttgctttaa ctggacttac
    76681 aatggcagaa cattttagag atgagcaagg acaagacgtt ttacttttcg ttgataatat
    76741 attccgtttc acacaagctg gttcagaagt ttcagcactt ctaggacgta tgccatcagc
    76801 tgttggttat caaccaacat tagctactga aatgggtgcg cttcaagaga gaataacatc
    76861 aactaagaaa ggttcaataa catctgttca agcagtatat gtaccagcag atgacttaac
    76921 tgacccagca ccagctacaa cattctctca cttagatgca aaaacagttt tatcaagaca
    76981 aatatcatca ctgggtatat atccagcagt tgaccctctt gaatctacat caaggattct
    77041 tgaccctagt atagtaggaa aagaacatta tgaagtagct agaggtgtac aatcaatact
    77101 tcaaagatat aaagaacttc aagatataat tgctatactt ggtatggatg aactatctga
    77161 tgaagataag ttaatagttg cacgtgctag aaagatacaa agattcttat cgcaatcatt
    77221 tacagttgct gagcaattta caggaaatcc aggtcaatat gttcctgtta aagagactgt
    77281 aagaggattt aaagaaattc ttgaagggaa acatgatgac ttaccagagt cagcattctt
    77341 atttgtaggg acaatagaag acgctgttaa aaaagcgaag ggaagtatgt agtcatggcc
    77401 agtgaatttt cattgaaagt tgtaactcca aataatactt tttatgatgg agacgttgaa
    77461 atgatagtag ttagaactac aaaaggagac aaaggggtat tgaaaggtca tataccattt
    77521 gtttcaggta tacctgtagg aactttaaag ataaaaaaag agggaagttt taaagaggcg
    77581 aaaatagcag aaggatttgt taatgtaact caagataaaa ctgtcatatt gacagaatct
    77641 gctgagtgga tttagtaatt taatttaaaa tataaaaagt cattttgacc aaaaaacttt
    77701 tgggtaaaat ggctttttta tattttactg ttaatagaat aacgataaaa ttgtaatctt
    77761 ttagtgataa taaattcaca aaatgtttaa atttactgca aaattatgtt gtaattaata
    77821 taataaagaa gatttagata gcttttatgt aagtgaaaaa gtcttcatat aagaaataca
    77881 tataaaattt ttataaaatt taaaaaattt gcttagttgt gtagtataat aaataatata
    77941 atagatttgt atgtaatatt cattacaaat aattttaaaa gttacagttt tattataatg
    78001 attattaaat taagataagt aacataaact aaataataat atgtattatc gatagtaaat
    78061 tcattattaa ttattgaaag aagtattgta aattttctgg aggaacaatg aatatatttg
    78121 atattggcgt agacataatt gaaattgaca gaataagaaa agctatagaa aagaataata
    78181 ggtttttgga gaagatattt acagatagag aaatagagta ttttaattct aagaatttta
    78241 aagcagaaag catagcaggt aatttcgcag ctaaggaagc tataagtaaa tctataggta
    78301 caggaattag agtgtttaac tttaaagata tagaagttct cagaaatgaa atgggaaaac
    78361 caatagtaaa aacttataat aatctagcaa aaatgtgcat agattataat gttttagaaa
    78421 taaaagtttc aatatcacat tcaaaagatt atgctatagc aaatgcgata accataatta
    78481 aggactaagg agtgattaca ttatgatgga taaaacagca aaagaaataa tgacaacaga
    78541 tgtaatagta gcaaaacaag atgatagtat agcagatgta gctaatatgc taattgcaga
    78601 aaaaatagga ggtctgccag ttgtagattc agagaataga gttgttggaa taatttctga
    78661 aacagatatt cttaaaaaag aaaaatatat agaagcacct ctctatataa atctattaca
    78721 aggattgatt ttcttagatg acttaaaaaa agtagaaaaa gatataaaac aagtagctgc
    78781 ttataaggtt ggagaactta tgtctaaaga tataataaag gttcatgaag atgataagtt
    78841 tgatgatgta gctaatgtaa tgattaaaaa atcaataaac agagttcctg tagtagatga
    78901 tgacaataaa cttaaaggta taatttgtag atatgatata ataaaagctt tatacaatga
    78961 ataaactgaa gtaggaggtg tgatgtgaga aaaaagtgga ccatagtatg tattatgttc
    79021 ttggcactgg ttataattgt aataggatgc caaaaacgac agtccacaaa agaagaagta
    79081 tacaaagatt ttcaaaagca gatttctgat atgaattatt acagttgtaa agctgaagta
    79141 gaagtagttg gaaataaaag cccacataat tatgttttaa ttcatactta taaaaaaact
    79201 gataactata aattagaggt aatttcccca aagcatttaa aagggaaaag tatagaatat
    79261 caaggtgata aaatattagt taaaaatcca aagattagtg atatagtcga gttgcctaat
    79321 acaggaaaaa ataatcaata tctttttata ggagacttta taaaaaacta tcttcaaaac
    79381 gaggagatga aagtaaagtt atccaaagga catttggttt tagagacttt tattcctggg
    79441 gataataaat attttaacaa gcaagtatta tatgtaaatg ctgacacaaa aaatcctgaa
    79501 aaaatggaag tgttagataa agagggagtg ccaagattta cagtaaaata caaagatttt
    79561 gaatacagaa actaaggggg actaaagaca tgcaaaaaat aacagtgcct acatgggcag
    79621 agataaatct agataactta agatttaact taaataatat taaaaattta ttagaagaag
    79681 atattaaggt ttgtggagta ataaaagctg atgcatatgg acatggtgca gtagaagttg
    79741 caaaattgct agaaaaagaa aaagtagatt acctagcagt agcaagaact gctgaaggaa
    79801 ttgaacttag acaaaatggc ataacacttc ctattttgaa cttgggatat actccagacg
    79861 aagctttcga agattctata aaaaataaaa taactatgac agtttattct ttagaaacag
    79921 cacaaaagat aaatgaaatt gcaaaatctt taggagaaaa agcctgtgtt catgttaaga
    79981 tagactcagg gatgactaga ataggtttcc aacctaatga ggagtcagta caggaaataa
    80041 tagaattaaa taaattagaa tatatagatt tagaaggtat gtttactcat tttgctacag
    80101 ctgatgaagt aagtaaagag tacacttata aacaagctaa taattataaa tttatgtctg
    80161 ataaattaga tgaggctggt gtaaaaatag ctataaaaca tgtatcaaac agtgcagcta
    80221 ttatggattg ccctgattta agattaaata tggtaagagc aggaataata ttgtatggtc
    80281 attatccatc tgatgatgta tttaaagata gattagaatt aagaccagct atgaaattaa
    80341 aatcaaaaat cggacatata aaacaagttg aaccaggtgt aggaataagt tatggactaa
    80401 aatacacaac tactggtaaa gaaacaatag ttacaattcc aataggatac gcagatggat
    80461 ttactagaat ccaaaaaaat ccaaaggttc ttattaaggg agaagtgttt gatgtagttg
    80521 gtagaatatg tatggatcaa ataatggtta gaattgacaa agatatagac ataaaagttg
    80581 gagatgaggt tatactattt ggagaaggcg aagttacagc tgagcgtata gctaaagact
    80641 taggaactat aaactatgaa gtgttatgta tgatatcaag aagagttgac cgtgtttata
    80701 tggaaaataa tgagcttgta caaataaaca gttatttgct aaaataaaac catgatatta
    80761 taatctggga ggcgattttg tgtacgataa gagtaaagaa aaaatagaag ttactttacc
    80821 agactctctg atttctgaag ttgatagtat agttcagatg gagaacagta acagagaaga
    80881 ttttgcaaaa gctgcttttc agttctatat aactcagaaa aagaaaattc atattaaaga
    80941 atctatgaaa acgggttata gagaaatggg tcaaattaat ctgtcactag ctgaattagg
    81001 tatgacagtt gaagaagtat cttctgatga taaaaatgaa gggaagattg cccaaggtga
    81061 gtactaattg tgaaataaag cgtggtgatt tatactacgc tgatttaagt ccagttgttg
    81121 gttcagagca gggaggcgtt agacctgttc tgataataca aaatgatgta ggtaataaat
    81181 atagtcctac agttatagta tcagctataa catctcagat taataaagcc aaattaccta
    81241 ctcatgtaga gataagttcc aatgaatatg ggcttaataa agactcagta attcttttag
    81301 agcaaattag aactattgat aaaaagagac tgagggaaaa aattggttgt ctagatgaaa
    81361 atatgatgat aaaagtagat gatggacttc aaataagttt gggattgttt actttttaaa
    81421 gagggatttg tcttttatta gacaatccct tttttctttt aaatatctct tagtgtttaa
    81481 ttttaatgta ctatgttaat aaaattaaaa ataacgcaaa aaaatagcat aaaagtgata
    81541 taataatatg gaattgatat aaaattacga actcaaggga ggtaattgca tgagagacca
    81601 taaaggatta aatgagattg cgcgtatcat aagaagagat atagtttcaa tgatacatag
    81661 agccaaatct ggacatccag gagggtcatt atcagtagtt gaaatactta ctgcgttata
    81721 ctttgatgaa atgaatgtgg attcttcaaa tcctaaaatg gaggatagag atagatttgt
    81781 attatcaaaa ggacatgctg caccagcatt atatgctaca ttggctgaaa aaggctattt
    81841 tgataaggaa gaactgaatg gattaaggaa gataggaagg atgttacaag gtcatccaga
    81901 catgaaaggc acgccaggtg tggaaatatc tactggttct ttaggtcaag gcttttcagt
    81961 tgcatgtggt atggctatgg catcaaagtt ggataatgct ccatggaatg tgtacacttt
    82021 gcttggtgat ggtgaggttc aagaaggaat tgtttgggaa gctgctatga gtgctgcaca
    82081 ttataaactt gataatttaa ttgctttttt agataacaat ggacttcaaa tagatggaga
    82141 tatagaaagt gtaatgagtt taggttcaat agttgataaa tttaaagctt ttggttggaa
    82201 tgtaattgag atagatggac atgattttga ccaaatattt gctgctcttg acatagctaa
    82261 atcaacagtt aaaaaaccta caatgatagt tgcaaaaact ataaaaggca aaggaatatc
    82321 ttttatggaa aatcaagcag gatggcatgg gacagctcca agtgatgagg agctagaaaa
    82381 agccttgctt gaattaggag gtgctgacaa tgagtaaaat ggcgacgaga gaagcatatg
    82441 gtaaagcatt agtaaaatta ggtcaaataa atgacaatgt tgtagtgtta gatgcagatt
    82501 tatcaaaatc tacaaaaaca catgattttt acaaggcatt tccagacaga ttttttaata
    82561 tgggtatagc tgaacaaaat ttaataggtg ctgcttgtgg attatcaact gctggtaaaa
    82621 taccttttgc aagtactttt gctatgtttg ctacaggaag agcctttgag attataagaa
    82681 attcagtttg ttatccaaag ctaaatgtaa aaatatgtgc tactcatgca ggtcttactg
    82741 ttggagagga tggagcatct catgaaagtg tagaagatat tgctataatg agagctatac
    82801 caaatatgac agttcttgtt ccagcggatg gagttgaaac agaaaaaatt atttttgaaa
    82861 tagctaagta taatggtcct gtttatgtta ggttaggaag aagttcagta ccagttttat
    82921 ttgatgaaga ttataaattt gaaataggaa aaggtacagt cttaagagaa ggaaaggatg
    82981 tatcaattat agcttgtgga attatggtaa atgaagctct attagcacaa gaaaagttgc
    83041 aagaagaagg tataagtgct agagttataa acatgtcctc gataaaacct atagacaaag
    83101 atttaatatt agaatcagca aaagaaacga atgttattgt aacagtagaa gaacatagca
    83161 taattggagg attaggttct gctgtaagtg aggtagtggg agagtcttgt ccaaccattg
    83221 taaagaaagt tggaattaaa gatacatttg gagaatctgg tactccaaat gaattgttaa
    83281 aaaaatatga attaacttgt gatgacatag taaagactgt taaagaagct attattgcaa
    83341 aaagaatgta agagatataa attattcatg tttgttaata atataatata tttaaaagag
    83401 agttataaag tgctatatta atttatatct ctcttttttt tatatgatat caatgtatca
    83461 aaaatgtaat aaaatattca aatttttaca aaaatagaga aaatattcaa atatatattg
    83521 actattcaga aaaatatgac taatatataa tttatagaga aattaatttt atatataatg
    83581 actacttaga taaaagaatc taaaaaatta tgaaaggagg actagggtat aaaattagat
    83641 tgtaagtttt aagttattat actaaaaagc tataaaacag ttatcatgta ttttatgtta
    83701 aaggaaattg taggtagttt atcgaattgt ttaagcagaa gaaaaaattt cacatgggga
    83761 ggtaactgag atatgtcaga aaaagtaaat gttaaaacag tcatcagttt cgcaggtgcg
    83821 tatgtagcaa cagtaatcgg ttctggattt gcaacaggac aggaaataat gcaattcttc
    83881 tctttttatg gttttgcagg tattattggt gggataattt caatggtatt attctcatgg
    83941 atgggtgctt cagttatgtc aaaaggtaaa gagcttcaac ttaaagaacc tatcaaaatt
    84001 tatcgtgttt attgtggtaa gtatttagga atattctttg aatggtttgg acctttattc
    84061 ttatttggtg ttttcgtagt aatgatttca ggagcaggag caactttaac tgaatactat
    84121 ggattaaatc catttgtagg tagagtaggt atggcagtag tagcattatt aactgtttca
    84181 ttaggtcttg atagattatc aaagatacta ggtggaatag ggcctataat aataatcttt
    84241 acacttttag ttggtggtat aagtttagct aaaaacatag gtaatatagg agaagctgca
    84301 caagttctta gcactgtaaa gatagctaaa ccagttccaa atgcttatct atctggtgta
    84361 atatatacta cttataacac aattgttgtt atggcattct taactggatt aggagcaagt
    84421 gctgctaaca aaaaagaagc tatttgtggt ggtatattag gtggagtagc acttatggct
    84481 gcagctataa tgatgcactt agctattctt tctgatatag gaaacttata ttcaaaagca
    84541 ataccatcat tattcttagc agataagatt tcaccaataa ttggagtttt attctcaata
    84601 attcttatat taggtatata tacaacagct gtacctttat tatggtcagt aactaataga
    84661 tttgtagatg ataatcatcc taagtttaaa ttaataactt taatagcagc tatattaggt
    84721 cttataggtg gattcctacc atttgataag ctggttggta ttttgtatcc atatactgga
    84781 tatatgggcg tcataatact ggtttgtgtt ctttatagac agattacaaa aacatctgga
    84841 tatcaagaag gaatcagtga caaataaata ttttttaata ttgtaaaccc aagagctata
    84901 tgaaaacaat aaaaatgttt tcatatagct ctttttattt tttagctcgt ttattatgaa
    84961 ataggaaaaa catgtttttt agttacatta catatattta taattatgga taaatatata
    85021 ctaatcaata atttagagtc taagataagt ttataaatca tatatttaga atatatggga
    85081 ggagtgataa gattggatgt aaagtttaat attaaaggta taatttatgg agttatagct
    85141 cttgtattcg ttataggggg atttatattc ataccaagta tgtttgtaga gaaatctaaa
    85201 cccatagatt atacagtatt acaaagaaat tcaataccag aaaagatact agatgtgatg
    85261 gataagtata caaatgaaga aagagcatta gcggctaaaa tcgataataa aatatacatt
    85321 atagtgacta gaggaaataa taaatatggt atagaaatgg acaaaataga aagcgtggtt
    85381 gaggaaggaa aggatgtttt gagagtcaag ataaagtata aagacaagga agattctttt
    85441 ccatacatag ttgttgaaac aaatatgagt gaacttccag atagaataga attaaatgcg
    85501 acgaaataag aaggtatttt ataattaaat aactgcatat tgtacaacaa agtcatggtt
    85561 tttattaatg taagtaaatt gtgtatggtt cttattgttg taaaagccat gacttaaaat
    85621 gcttataaag taagatatta acagtagaat ttattactat attaaataag gtctggaagt
    85681 acttaatgtt ctaattattt ggagtgataa ttctagtttc agtaactatg tagtctaatt
    85741 gtgcatcatg agtttctttt ggaatagaat tgaatatctg gaagtcaaat gctatgccta
    85801 tagttatagc atcttttctt aagttttcta aaaatctatc ataaaatcct ccaccatatc
    85861 ctaatctata gcaatgtata tcatatgcta cagctggtac aattacaaca tccaaggctt
    85921 taatatcaat tttaggtgat ttttcgttag gttctcttat tccatatgct ccgattctca
    85981 atccatcttt taaatctgtt atttgagtag ggattaatgt acgattttct tttattgtga
    86041 taggacttga tactattttc tttagagaca aaagtttttt gattaaatta tctgtttgaa
    86101 cctcattgtt aaaatctaga taaagcatta tattagttgc atttcttatg tcttccattt
    86161 gaagtaattt ttcagttatt aaatttgaat tactaagtac gaaatttgca tttttatttt
    86221 ttcttgattc aataactttt tttctaaatt cttttttcat aaaataattc ctcccttaat
    86281 gtgttataat gtgtacagca attgtattta atataaattt tagtataatt tattgtaata
    86341 aagcaatata tttgggtaaa tgtaataaaa ataacagcta gtcatataat aataatagtt
    86401 tatgtaaaag gagatgtatc ttgtgatttc aaagaagaaa gctatttttt taggggtgat
    86461 tttaataatt ataacagcta tggttacatc agcatttcag ttgacattgg ggaataaagt
    86521 tgtaatatcg aaagaactct atgaagacta taaaaaatat gataagttgt taggactaga
    86581 atctattata aaacaagatt tttataaaaa agtatcagat actgatttgg taaatggagc
    86641 atcaaaaggt ctatttctag gaacaaatga taagtattct ggttattata ctaaagatga
    86701 aatggaaaat ctaattaatg atagtgaagg ttcttatgtt ggtgtaggta tgtatatagg
    86761 ggcatcaaaa gatggtggct tagtagtagt tcctatgaaa gattctccag cagaaaaagc
    86821 aggtgtaaaa tcaggagata aattagtaaa agtcaatgga aaatctgtct catataaaaa
    86881 ttcagatgaa gctgttcgta tgatgaaggg taaaaagggg aaaacagttg agctgactat
    86941 attaagagaa gataaacaat tgaactttaa agtaaaaaca gaccaaatag ttgagaagag
    87001 tatagagagt aaagtaattg ataatgattt aggatatata gaaattaccc aatttatatc
    87061 aagtacatat actgactttg ataaagcttt aaaagaatta aaagcaaaaa atatcaaggg
    87121 attagtaata gaccttagaa acaatcctgg tggaatgcta gatatatgta aagaagttgc
    87181 tgatgagtta attggtgaag gaactatagt atatacaaaa gataataagg gaaatactga
    87241 gtatttgaaa tctgataaag aaaaattggg acttccaata gtagtattga ctaatggaga
    87301 aagtgcctct gctgctgaaa tattaacagg tgcaatcgtt gacaataaag aaggtatttc
    87361 tgtaggtact acaacttttg gtaaagggtt ggtacaatca gttgtaagac tgaaggatgg
    87421 aacaggttac aaactgacta ctgcccaata ttttacacct aatggagatt atatcaatga
    87481 aaaaggtata aagcctacaa ttgaagaaaa agatgaaaat aagcaattag atgtagcaac
    87541 taagtggctt agagaacaga ttgataaata ggatttaatt cttataaact tatattataa
    87601 aataaagagt cttataaaag gagtgtctca aaatgaaatt tttagttcat gaggcacttt
    87661 tttgtaagat gtcgaatgta ttttcatcac tttaacaatg aaaaagaggc ttatctctat
    87721 ttttggacag cctccataac tttatattta acctatttat taactttgta cttacatata
    87781 ccatttatat aagtttcgtg tatattaaag cccttatctg ttactataaa gtctgcatcc
    87841 ataccttgat atatggagcc acagacatta tcaatattac aacttaaagc aggtacatat
    87901 gtagccattt ttattgcatc ttctaaagtc gatatattcc aatcaaccat atttctcaca
    87961 gccctgtcca tagttaatac actaccagct aaactcccac tacttaatct tgcaacacta
    88021 ttttttacat ttacattaaa cttaccaaga gtgtattttc catcctccat agcaccagcc
    88081 ctcatacaat ctgtaattaa agctatgtta ttactagact tagcatccat cattatttta
    88141 atagctatgg ggcttacatg atgaccatca caaattaatt cagcataagt atcttttagt
    88201 accatagcag ctccaaccat tccaggttct ctatgattta aagggctcat cccattatat
    88261 gtatgtacaa acactttagc acctgaatta acaacttgtt taacttgttc aaatgtagct
    88321 gaactatgac caagagaaac tgagatatta tttttagttg catattttgt taattctatt
    88381 gaacctttac gttctggagc aattgctatt tttcttatta aatttttcga ttttttttgc
    88441 cataatttta atatattgat gtcagggtct tgaaaatatt tttcattttg agcaccctta
    88501 tatttttctg taaaaaatgg accttctaaa taaatccctt gtatttttgc cccctcaact
    88561 ttattgaaac tattgcttat attttctaca gaatcactta gtgtatctac ggaatcagtt
    88621 aaagtcgtag gtaggaaaga tgttactcca tattttaata agccttttga aatcgtgttt
    88681 attgcttcaa atgtattgtc catgacatct gcacctaaaa gaccgtgaat gtgagtatca
    88741 actaagccag gagcaatata tttacctgaa aaatctataa cattatcagt agtactaggt
    88801 ctttcttgct gaaattcacc gaatttgcca ttaattatac taaggtaacc tttttctttg
    88861 gttccatgtt tcataaaaaa tttatctgca taaataaaac ttttcaaaac tgcctcctta
    88921 taattatgtt attattgtgt tattgacgtt tataatatca ttaagtttta ttgaaattta
    88981 tttaatttac tatcttacat gccttactct atatacaaat ttatcgcttc tagcaacact
    89041 caaagtaaat tcaatgacta tattatcatc attgtatgtt gtacgaagta attttagaca
    89101 aggtgaatct cctggtactt ctaatagcgt tgcttccttg tcagatatta ttccagctga
    89161 aaattcttca tcagcaactt taataacctc accataatct tctctaaata tttcatataa
    89221 aggtttttgt tcgatttttt cttttgtcaa tcctataaat tctttcatag gtagatatgt
    89281 tctttcaagc atcataggaa ggtcattagc aagtcttaaa cgcattattt ttattatttt
    89341 ttcaccagga gttataccta atttttcaga aaaatacttt gtactttcta ctacctcaaa
    89401 tgataatact tttgtacttg gcttttttcc ttgtgttctc atataatctg taaagctata
    89461 actttccatt aagttttgag aattttgact gagtgcagca acaaaagttc cttttccatg
    89521 tcttttatat atatatccca tatgttctaa ctcagccata gctagtctaa ctgtagttct
    89581 acttactcca tattcatcac aaatttttct ttccgaaagc attctatcgt ttggttccat
    89641 ctcattttca atcttagttc ttaatatttc aacaagctgg tcatatattg gtcttttatc
    89701 atttcttttt atcataaaaa tatagtcctt tctaagtggt tattaccaca atttgattat
    89761 agaatataga attatttatg tcaatgaata aagtttaatc aaaactcaat aagtaagtct
    89821 attaatttat tataaaatta tggtacattg acaaaacaag taaaataatt tatattcaaa
    89881 ttggtaataa ccactttggg tatattgtag acgaggtatt ttttatttta catattaatt
    89941 tattgtttag aaaagtaaaa aattaataat gaggagaatc tagtatgatt acagtaataa
    90001 catttaaccc atctatagat agaatgtata gggtaaataa tataaacata ggtgaggtgc
    90061 aaagggtagt aagtaagaat gcaactgctg gaggtaaagg attaaacgta gctaaggtat
    90121 gtaaaatttt aaaagaaaat cctttagcga taggatttct aggtggattt aatggagaat
    90181 ttataaaaaa tgaacttaaa aaattagaga tacaaaataa gtttacaaaa atagagcagg
    90241 aaactagaaa ttgcttaaat ataattgagg acaataaagt tagtacagaa tttttagaaa
    90301 aaggaccgat agtagaaaaa agcgatttag agagatttga aaatgatata gaggaagtat
    90361 taaaaaatac taaaatacta gtggcatctg gtagctattg tgagaatatg ccgatagact
    90421 attatgaaaa gataggcaat atatgtagag caaataatat aaaatttata ttagatacat
    90481 caggagaagc attaaaaata gctttaaaat caaagccgta tttaataaag ccaaatatag
    90541 atgaaataag acatttatta ggaataaata tagaatcaag agatgaaatt atcttatcag
    90601 gaaaaaaact tattgaaatg ggtgcagaga atgtatgtat atccttagga aaagatggta
    90661 tggtgtattt aaataaagat agtgtatatg atgtaaaagt accagttgta aagtgtataa
    90721 atactgtagg tagtggagat agcacagtgg ctggatttag tgtaggtatt ctaaggggtt
    90781 ataaaataga aaatttactt aaatttgcaa atgcttgtgg tataagtaat gctttaaata
    90841 tggaaactgg atttgtagat ttgagagaaa ttgataaata tcaagattta gttgaagtaa
    90901 aaaagttaag ttaagtatat ttaatgtgaa tatactaagt ttaatgttgt tgtaatagat
    90961 ttaaaattta atataaaaga tatagtctta tataaaaata ggttagagaa attcatcttt
    91021 aacctatttt tataataaat atctatttta ctgaatttat aattttttct agtaatcttt
    91081 gagccttgac acactcttct ccactaatag ctggttttat attattttct atacaatcaa
    91141 taaaatgatt tgatatatct tcaaaaccct tttgttttaa tatatttacc catgcaccac
    91201 tttgttttaa aattaggttt ccaccttctt ctatttctag tacattaaga ttcttaattc
    91261 tttgaatcct gccttttgaa agaatttcaa cttgttctaa ctttgttcca gaatctctat
    91321 gcatagaggt gtttatagag aaatgtttac ctttaagttt atgacttaca aatataagat
    91381 tcttattgtc tgttaaaaat aaatcttctc cactaatttc aacatcttca tttgctaacc
    91441 ataaagcagt gtcaataaca tgtatataat catctataag ggtactgtcg aatctaacat
    91501 ttcttaagga atttaatcca tgtttacata tattgataga tacgatttct gtagcattat
    91561 ttttaatttc tttgtacata ggacagaatc tacggttgaa tccaaccatt aaatttaagt
    91621 tttttttcgt acttaattcg ataagttctt ctccttgatt tactgttgaa gcaagaggtt
    91681 tgtctacata tacatgaaca cctaaattta ataatatttt tataatttcg tagtgtgttt
    91741 ctgtagagct atgtagaaaa atgcaatcac attttttagc taaagactca atagaatcga
    91801 atggcatgat tctataatca ctacagattt tttctctttt aactttattt ggagtaaaag
    91861 ctcctacaaa ctcaaatctc tcagatttag ttaatatagg taaatatgcc ttttgagcta
    91921 tggagccaag acctatcatt cccattttta tatttttcat aatactttct cctaaggttt
    91981 ttatatttac agaattgatt ataattcaga cacgtaaatt tgtaaacttt gtatcaaaaa
    92041 ataaacttaa ggcttatata agtaaattag caaaataaga aatattaata aaataatttt
    92101 gtaggatatc tataaaattg atttatataa atattttatc tattgacaaa aaattcaaat
    92161 taatttatat ttggattagt ggtaattacc actttggtct gaacaagttt ttatcgtaaa
    92221 ataaaaatac taaagtatct agagtatgat tttattaaat ttttaaagac aaactataaa
    92281 aataatcaaa atatatagag tatattttat agtgagttta agtagtaata aaaaatctag
    92341 gcaagaaatt aaaagaaggg tatatttttt tataccttaa agtggttata acctcattac
    92401 caaaaataaa tgttgtaagt atgaaaggag aatgaaaatg tttaagttag aagaacaaaa
    92461 actaaaagat ttaggagcaa taataacaac taatgaaata aaacaacaac ctgaattatg
    92521 gttagaaact tatgaaatct ataaatctaa caaagaagaa ctacgtagat ttatagataa
    92581 aataagtaat aatcatggac agtttagagt tatatttaca ggtgctggaa cttcagctta
    92641 tgtaggaaac tcaatactac cttatcttaa gaataacaat gacataagaa aatacatatt
    92701 tgaagcaata cctactacag atatagtttc aaacccatat gattacttaa aaaaagatgt
    92761 accaacgtta ttaatttcat ttgcgagaag tggaaatagt cctgaaagtt tggctgcttt
    92821 aaatttagga aataagattg tagataattt ctaccattta gctataactt gtaatccaca
    92881 aggagaactg gctaagatga ctaaaaacga cgaaaataat tacttgttat taatgccatc
    92941 aaaatcaaat gatgaaggct ttgctatgac aggaagtttt tcgtgtatga tgttatctgc
    93001 tatgttaata ttcgatagct tagaagatga tgtagaaaag tcatatataa atgcaataat
    93061 tgaaatggga agaaatgtta tagatagaaa agatgaaata catgagttaa taaataaaga
    93121 ttttgataga gttgtgtatt taggttcagg aggattaggt ggtttgacac aagaagcaca
    93181 actaaaactt ttagaactta cagcagggaa aatagctacg gtgtatgatt ctcctatggg
    93241 gtttagacat ggaccaaaat catttattga tgaaaataca cttgtatttg aatttgtatc
    93301 taactgttta tatacaagaa aatatgattt agatgtttta gaggagataa aaagggataa
    93361 aattgctaaa ttcacttgtg cagtgtcagt agaaaatgaa aataacttct caggaacaaa
    93421 gtttgagttt aaagaaaagt ataataaatt accagatgtg tatcttgcaa tgccatacat
    93481 attgtttgca caaactatag cattgtttgt atcggtaaag gttggaaata agccagatac
    93541 gccatcagct acaggaacgg taaatcgagt agtaaaaggt gtaacaatat atgaatatta
    93601 gaagagaaga ttaaaatatt ataactaaat aatttgggag ggtattaatg tggcattagt
    93661 aacaacaaca tcaatgctta aaaaggcaca agatggggga tatgcagtag gagcatttaa
    93721 tgtagaaaat atggaaatgg taattgctgt tatagaagct gctgaggagt taaattctcc
    93781 agtaatatta caaactactc catctactgt aaaatatgca ggtctcgatt attatctagc
    93841 aaatgcaaag gttgctgcgg aaagagtaaa gatacctgta gcaatgcatc tggaccatgg
    93901 gtcaagtttt gaccttgcaa tgaaagcttt aagaagtgga tatacatcaa taatgataga
    93961 tggttctcat gaaagctttg aaaataatat atctatatct aaatcagtag taaaagcatg
    94021 tagcccttct cttataccag tggaagcaga gcttggaaaa gttggaggaa aagaagatga
    94081 tttagatgga gggaatagta atgattatac aaatccaaaa gaggcaaaag agtttgtcga
    94141 tagaacagga atatcttcat tggctattgc tataggtact gcacatggat tgtataaggg
    94201 agaacctaaa atagatttag ataggttatc agaaattaaa aatgtagttt caataccttt
    94261 agtattgcat ggaggttcag gaatacatga tgatattata aaagaagcta taaaaagagg
    94321 tattgcaaaa gttaactatg caactgaatt aagaattgca tatagtaaag gggttaaaaa
    94381 agttttaaat gaagattctg aggttataga ccctaaaaag tatggactag cagggcttca
    94441 atcagtaaag gattttgtaa aagaaaagat taaagtatgt gggtctgtaa ataaagtata
    94501 aaaaataaaa tatcctaaat ttattttaga taagtttagg atatttgtta tatgaaaatt
    94561 ttatattaat tatgggtaaa tggtgtattt ttttcattta attgatgaaa aatatcagct
    94621 tttattggta aagtattaca tatataatta aaatataata aaaattgaac tatatatttt
    94681 attattatga aatatggata ttaaatttta gtgctaaaat gtacgaggat ataatattct
    94741 ataaatgaaa acaaaaggtt gactttataa gaaaaaattt tttatgctac tttgaaaaat
    94801 acaataataa cactgagaga ggtggggata tgagagaacg cattattctt gaagcattaa
    94861 aaaatagtag tggttatcta aacatagatt attttgcaga taagttgggg gtatctactc
    94921 gaactatcag aaatgaaata aaaaagatag aaactataaa agaatgtaat ggtttcaaat
    94981 tagaatataa gtctaaacta ggatatattc taaatattaa agaccaagat aaattcgagc
    95041 attacctaag aaacttaccc tcagatttag ttgaaaatcc agaacaacgg ttagaatcta
    95101 taatagtaga acttttagta aatgaaggtt ataaaactat agaacagtta agtaaaaaat
    95161 ttttagtaag ttcatctcaa ataaaaaatg atttaaaaaa gatagatgaa aaaataaagg
    95221 atacagaatt aaaattggag cgaaaggctc attatggaat aaaaatagaa gggtctataa
    95281 aagaaattca aagtatactg gtggatagtt actttaaagg gaatagaaat ataacaaaat
    95341 acagaaataa atttatagat aatattaaac tagataatat cagaagtaca ataaaaaatg
    95401 tacttaatga acattattta gaagcaaatt taaccgaact tgaggaaata ttagcacaaa
    95461 ttattatatt gtatataaga gttagcacta gagtagtaag aagtcctagt gatttagaat
    95521 tatatacaga agatttaatt atagacgaat tattagataa aatttttgga gataagaagt
    95581 atagccttac ttatgatgaa aagtattatt taaagcaact tataaaatta aggactaagg
    95641 ataagaaagc caccataaag aacattgata agaataaact tcaagatatt atgtgcgaat
    95701 tttttagaga tatcgataaa aagtataact ctaatttttt agaagataaa gagttcctta
    95761 acttatttta tttacatatt gcatgtttaa tagaacgtat aaagaagaat cacaagataa
    95821 caaatccttt ttcagttaaa ataagtcaac agtatccaac tgtttttaat ttatctattc
    95881 aattttcaaa aatcatagaa aatgagtatc acataaaaat aagtcaagat gaaataggtt
    95941 ttatagctac tcacattgct gttccttttg aaaagagaga agaggctaat tttaataaaa
    96001 aatataaaat agcaataata tgctcttctg gtggaggcag tgcatttttg ataaatttga
    96061 gacttaaaga aatctttcca aatgctgaaa taaaaaactt ttcattacta gaagaaaagg
    96121 ctgtaataga atttgcgcca gatttgattt tttcaataac aaatctttta tttgaaataa
    96181 atgctccagt tatacttata aatgaaattt tagacgaact ggattatttg gatattaaag
    96241 aaagttttag atttgtagac catataggaa atgtatcaag cccaaaacaa tatatattag
    96301 gtctgtttga taagaatcac tttaggtgtg taaaagagaa aaccaaatat aaagatatcc
    96361 ttgatagtat gtcgcaatgt atagttgatg agggagcttg ttctccgact tatcccaaag
    96421 atgtgtggga aagagaaagc tatttgagca ctatttacac aaatggtgta gcgatacctc
    96481 atccaattga aatgacaggt aataaaaata ttatatcagt agccttgata caaactgata
    96541 ttaattatga aaatagggta ccaaagatta ttttcatgat ttcattaata aagggaaatc
    96601 tagagcttca taagcaaata tctaaatatt taagtaagat tatgacagat aaggatatgg
    96661 tagatatgct aaataagtca caatcttatg aggaatttat gtataagcta aaaatctatc
    96721 tgggaggtta gacatgaata tagagttttt taagaggtta tcagaagcag atggtatagc
    96781 atctaatgaa gaagaggtta gacatgtttt attggaagaa ctaagagctt atagtgataa
    96841 agttatatgt gatggtctag ggagtataat tttttctaag ataaaagatg aaagtgcacc
    96901 aaacgtaatg atttgtgctc atatggatga agttggattt atggtgagaa gtatagacaa
    96961 acttggtatg attcacctaa tgacaatagg aggagtaaaa cctcttgcac agtttgtaca
    97021 aaaagttaga attacaacaa aagaaggaaa gaaaatccac gctatcataa atgctacata
    97081 taataatggt aaggctgaaa atatatatgc agatattgga gcatatacag aagaagatgt
    97141 atacaaccta gggattaatg ttggggatat ggtaacatat acaacaaact ttgaggaatt
    97201 tactttgcca gaccgattag tgggaaaagc ttttgatgat aggataggat gttttgtgat
    97261 gggagaagtt ttaaaggaac ttaagaaaga aaatctaaat tgtaatattc attttgcagc
    97321 tacaagcagt gaagaagttg gaataagagg ggcaaagacg tcaacgcagt taataaatcc
    97381 agatatagta tttgtaatag atgtagcatg tgctaagaat gagtttgtga gggactatac
    97441 aaatcagaaa caaattgata aaggtgtaat gctaatgcat agagatagga ctttagtccc
    97501 tagtagaaaa atgatagatt atgtaatgaa aattgctagt gaaaataata taccacttca
    97561 acatgatatg tttgaatcag gtgggactga tggaggagaa gcacatctcg taaatgaagg
    97621 gaaaccttgt gtagtaactt gtgtaccagt tagatatggt cattgtgcat tttcaatagt
    97681 aagtaataaa gatttggaaa acattataag attgtataca cagttaattt taaattttga
    97741 tgaagaaaaa tatagacata taagaaattt tatctaaagg agaataagaa aatgtcaaca
    97801 gaagtacaaa taatggaact tatatcaact gcaggagaga gtaaatcgaa agcttttgag
    97861 gctttaaaaa aagttaagtc aaaagatttt aaaggagcaa aattgttaat agaggaggct
    97921 cgtaaaatag atattgaagc tcacaggata caaacagaat taataactca agatttaaat
    97981 gaagacgttg aaagcccagc aatgagtctt ttaatggtac atgctcaaga ccactatatg
    98041 acttctcagc tagcaaaaga cttgatagag gctttgatat attgtcttga taagtaattg
    98101 taatgtagaa atagattatt tatgtaaaaa ttcttttaaa agtttagatg cttttaagag
    98161 ataataaaaa tacaaacttt aggaggaatt attatgaaaa tattattatg ttgtgcaggt
    98221 ggattttcta ctaatatgtt aatgcaaaat atgaaaaagg tggtaaaaga gagtgctaaa
    98281 ctcaatgaaa aagattttga gtttacagct ataccagcag attcaataga aagtgaagtt
    98341 gatgactggg atatagtact tatagggcct caaatagctc acaaaataga tttcttaaaa
    98401 ggaatattag agccaaaaaa taaacctttt gcagtaatag ataaagatgt atatggaaaa
    98461 atggatggag ctacagttat gaagttggca ttaataactt ataagaaaca tcaattagct
    98521 caaggataat aaaaataatg agggaaaagg gagattagat atgttttcaa aatttgaagc
    98581 atttatgaat agagtattta tgcctttagc tcataaggtt gacaatcaac gtcaccttgg
    98641 ttctataaag gctggtatgg ttgctatgac accattcaca atattaggga gtatatttgc
    98701 aatacttcca gcacttccaa atatgcttgg agaagataat ccaataagca aattcatact
    98761 gaacaattca gcaatattgg acttaccagt aagtctttcc ataggcttaa taggattata
    98821 tgcttgtatg tgtattgctt ttaatctggg gaactactat aaattatata taccaggttg
    98881 tgttgcacta tcaacttttt cttttttatt cctagtagca tcatttacac cagatggagc
    98941 tttagaaata ggaaatttag gagctaaagg actatttaca ggtatgatag cagggcttgg
    99001 ttctgtggag ttatataatt tttgtaataa gaagaatatc acaataaaaa tgccagaaaa
    99061 tgtacctgat tttgtatcta ggtcttttga attaatacct actactataa tagtttgtgg
    99121 aacttttata gttgctcgtt ttatttcatt aaaaatattt ggagaattac ctccacagat
    99181 acttactcaa tttttatctc cattagtagg aagtatggat aacccatggt cagttcttgc
    99241 acttaacttt gctatatgta ctatattctt ttttggaata cattcatcag tatttagccc
    99301 tataactaga cctataatga ttacatttat agctgaaaat atagcagcta tgcaagctgg
    99361 agaaacaata cctcatttct ttacagcagg agcttcaagt gcattctttg gatttacagg
    99421 atgtggaatt agtataggtt gtgtaattgc atgtatgtta tcaaaaaatg cttcctataa
    99481 gaagattgga cgtgtatcat tattccctgc attatttggg ataaatgaac ctatattatt
    99541 tggagcacca ataatattaa atccaataat gtttatacca catgtatttg gtggagctat
    99601 aataggtaca ctaccaatgt tttttatgca ctggggatgg ttagcaaagc caatatttga
    99661 ccctccatat gtaggagtat tcttagaagg atttttaact aatggagatt ggcattctat
    99721 attagcaaat gcattgcaat tagtattaac agttttatta tattggccat tctttaaaat
    99781 aatggaacgt caacaaaata ataaaaaaca aaaagaagaa actaagaata tattctctaa
    99841 agaagaagaa gacttattgg atgatttagg attagatttc taatattttg ttatgaataa
    99901 tacaatagag agactagtat ccttaatcga taaaagaggt gttgacgctc ttttgattaa
    99961 agcaaaaaat actaaaagat atataggggc attatcaggt agtggtgtat atgtgcttgt
   100021 tactaaagat aaaaattatc aagttctaga tggcagatat attgatgaag cagataaaaa
   100081 aacgactggt tttataaaaa ggattgtatc tcaaggttct tatataccaa ctataattga
   100141 gttattaaaa gaattaaata taaaaaagtt agcgatagaa aaccaagcta taagtataca
   100201 agagtatctt tcactaaaaa atgcaggttt taaaatcaat ttaataacaa atgaattatg
   100261 gaagctaagg gctataaaat ctaaagaaga aattgaactt attaaaaagg cttgtgagat
   100321 tacagatgaa gtatttgatg aggttatttc tgaaattaaa aaagatatga ctgagctaga
   100381 agtatcagct ctaattcagt atcatgcatt gaaaaaaggt gcaagtggaa tgtcttttga
   100441 gacaatagtg gtatcaggag aaagaggtgc aatgccacat ggaagaccta caaacaaaaa
   100501 gttgaaagtg aatgaagcta taacaataga ttttggtgtt gtttatcaag ggtatcaatc
   100561 agatatgact cgtacaatat ctataggtaa acctcctaaa attattaaag agatatatga
   100621 tgtagtattg gaagcacaat tatctgcaat agagtcaata aaggaaggaa ctagggcaag
   100681 tgatgttgac aaagtggcta gagaaattat agataaacat ggatttggcg aatattttaa
   100741 tcatggactg ggccatggta taggtcttgg agatggtgaa gttcccactc taaatccaaa
   100801 tagtgaagat atattagtgg agggaatggt aatgtcttgt gagccaggta tttatattcc
   100861 aaatgtaggg ggagttagaa tagaagatga cattgttata atagatggaa aaggtgttcc
   100921 actcaataag acatccaaag agtttataat attaggagaa taaaattatg aaatataatt
   100981 ttaataaagt attaaatcgt aaagaaggaa attgtaggaa atggagcaac cacgtaatta
   101041 aagaaaaatt cggcttaaat gaagatgcaa ttcctatgga tttagctgat attgattttg
   101101 agtgtgctcc tgctataaaa gaagctatct taaaaagagc atcaatagga gattatagtt
   101161 atacttttat aggagatgac ttttatgatg ctattataaa ttggaataaa agaagatttg
   101221 atgtatatat agaaaaggat tggataaaat taacttttgg tactgtttca acccttcatt
   101281 atatagtcca agcatatact aaagaaggag aaggtgtatt gataaatact cctgcttatg
   101341 acccttttgc agaggctgta ttaaataata atagaaagtt gtgttgtagc tcattaaaac
   101401 tagataacaa tagatattat ttagatttag aggatatgga aaatcaaatg aaatacgaga
   101461 atataagatt gcttatattc tgtagtccac aaaatccatc aggtcgtata tggacaaaag
   101521 aagaactata tcaagtgtca gagttatgtt taaagtataa tgtaattttg gtaagtgatg
   101581 aaattcatag agatataata tttaaagatt atagatttgt atctttgtgg aatgctcatc
   101641 cagaaattta taaaaatagt ataatctgtg tatctcctaa taaagggttc aacttaggtg
   101701 gattaaaaac atcatatgta ttaataagag atttaaaaat tagggagact ttattagaaa
   101761 ggctaaaaag taattcaata acttctccaa atgtatttgc aataccagca atcgttgcag
   101821 catacaatga aagcgaagaa tggctagatg ctatgactag ttatgtagag gagaattttg
   101881 aaatagttta tgatttcttt gaaactcata taccaaaagc caatgtgatg aagtcagact
   101941 cttctttttt agcctggata gatgtaagag gagtgtttag aaatgaagaa gaatctaaag
   102001 aattttttag acatgcaaac ttaactatgg tagttggaag ttattttgtg aaagatggag
   102061 atggatttat tcgtattaat gtgggatgtc ctagagaaac attaaatgag gctctaaata
   102121 gaatcaaaaa aacgtatata agtatgtatt gttaaattat aaaaaaggta tatatggttt
   102181 atataaaaac acattattta gttatcaaat attactggaa ttttgcattc cagtaatatt
   102241 ttttgattaa ggaatattat tgaagaatat taaataatat tatttcatat ccttatatta
   102301 acttatataa aaatatttta ttattttggg aacgggttag ctaaccttta tctagtttat
   102361 atttatactg taagaagcag taaaaacttt tcctttactc agtttattaa taaacttctt
   102421 atctttataa attttattag aatttatatt atcagcaaga ccataccaag gttctatgca
   102481 taaaaaagga gcagtagaat tggtttcact ataataagga gtccaaatac caactagagg
   102541 gaaatctttc atagatatag ttacatattt actaccatta ttattacata tagatacttc
   102601 atctatgttg gtgtatatca aagcatcatt cttgaataat tctggattta actgtaagtt
   102661 ttttaatttt ccaatagata ttatatcatc cgtaaaagaa ccacttaaat tgattttttc
   102721 tacatcattt ctacttttaa attcaaggta gtgtttagaa aaatcatttt gttcgcaaga
   102781 aggaaggttg aatgcaggat gtccacctat agaaaagaat atatctttag agtcagtatt
   102841 tttcacaatc cattctacct caatgctgtt atcatttaat gtatagttta tgattagctc
   102901 aaaagaatat ggatatttct ttaaagtaga ttcattatct gttaatttat aagatacgaa
   102961 tgtatctcct ttatctacaa tctcaaagtc catatctcta gcaaatccat gctgagtcat
   103021 actatataaa ttttcttcta ttattgtttc attatcaaaa agtttaccta ctataggaaa
   103081 cagtataggt gattgtctac cccaatattt tttgttacca ttccaaagaa tatttttgtc
   103141 gtatttttta gaaaatattt tagttagttc agcaccaaaa ctgcttgatt cgataattaa
   103201 attttcattt tgtaatatat tcatttaaaa tctcctttat tatattttat gagtatatta
   103261 tactataaag tataaagatt attaaatttt atttgatatt atatttgaaa ggtagatttt
   103321 agtatatttt gaaaattttg ttttgaaaat ttgggattat ttaagaaatt ttgtattata
   103381 aatagaagga aatagataaa ttgtatagaa taaaatatat taagataagt taataatgtt
   103441 aaatgggaag tgagtttatg gaaaaaccaa atacaaaagt tgttaacttt caagagtata
   103501 aagacagaaa aaacaaaaga gaagtaaata gagacgaact tttaaagctt ataaaaaaaa
   103561 ttgtaacttc aaaataggga gttgttaaac tccctatttt aatgggtttc ataataatta
   103621 agacattcta agtccatcta tataatcttt gaattgtgag aaatctgatt cactacttaa
   103681 ttctatagtt tctgaacctt ccgtataaaa attcttaaga tagatagtat aattattatc
   103741 aacacaatca tgataaatac atctatatcc atcttcatac aagcttttta acttagaaaa
   103801 atcatccaca atatcatctc cttaaagttc ttttaaatat atttttacaa aaagcatcta
   103861 attgtatgca aattgaaaat gtaaaataaa ggaaatgaat ataaaatgta gaataatttt
   103921 tatatgtatg taaaaataaa aagaaaaagt taaaattttt agaaaataag agtgtttttt
   103981 atctaaaaag agagtttaaa aaataaaaaa atgttgggag gataaaaaat gagtttatta
   104041 gaaagtatat caaaaaacat atattcccta gatagttctt ctattgaaaa aacaaagcag
   104101 agattggata ggcttataca tccaactgga agcttaggaa aaatagaaga tatttgcatg
   104161 caattagcag gaatatttgg taatgaaaat tttgatacga gcaaaaaggt tataattgct
   104221 tttgctggag accatggtgt atatgaagaa ggagtagcac ctgaccctca aaatataaca
   104281 aaactacaat ttccaaattt ctctaaaggc ctatgtggag ttggagtaat aagtaaattt
   104341 gtaggggcag atgttgtagc tgtagatgta ggaataaact gtgatgaaaa actggatgga
   104401 gtattagatt acaagataag aaaagggaca tcaaatatgg caaaaggtcc agctatgagt
   104461 aaacaagaag ctattagatg tttagagata ggtattgaaa tagcagaaca gtgtatagaa
   104521 aaagattata aggttattgg tattggggag atgggtatag caaatactac tccgagcaca
   104581 gcaataatat ctgtaatttc aggttgtgac ccgttagagg ttactggtat aggtgcaggt
   104641 cttaagaaag aaagactaaa gcataaggct gaagtaatta gaaaggctat tgaaattaac
   104701 aatccaaatc caactgatgg agtagatatt ttatctaaag taggaggatt tgaaataggc
   104761 tcaatggcag gtgttatact aggttgtagt gctaatagga ttccagtagt aattgatggg
   104821 tttatttctt atgcagcagc attaattgca tataagataa atccaaaaac tagagaatat
   104881 atgatagcat ctcatttatc agcagaatca ggaactaaaa gagcattaga catattaaaa
   104941 ttagaccctc tattaaatat ggatatgaga ttaggtgagg gaagtggagc tgctttagca
   105001 tttaatataa tagaagcttc aaattatact tacaaaaata tggcaacttt tgatgaaatt
   105061 gacatgggaa gataaatata aaaatttaat atgtaggagt gttttgatga gtaaaattat
   105121 tctagtaaca ggaggcgcta ggtcagggaa gagtaacttt gcagaaaaac tatgtttgga
   105181 cagaaataat aatacagctt atatagcaac ctctattcca tttgatgatg aaatgaaaga
   105241 tagagtaaaa aaacatcaag agaatagacc tagaaactgg aatacctatg aaatatatga
   105301 agatatatat tccataatta aagagatata taaagaacat gaaactgtca tactggattg
   105361 tgtaacatta ttagtaaata atctaatgtt taaacacaat ttaaatatag aagagtctag
   105421 tcaagaagaa ataaacaaat tagaacaata cataaaagaa caagttgtca aacttattga
   105481 agaaatagaa aaaacaaatt tatactttgt atttgtaacg aatgaattag gtatgggaat
   105541 tgttcctggg aataaactta gtagaattta tgctgatatt gcaggtcgca taaatcaata
   105601 tatagcgtca aaaagtaatg aggtttattt tgtagttagt ggcataccta tgaagataaa
   105661 ggagtagtat gtgattatga aaagatttat tttaatacta cagtttttga caaggatacc
   105721 tataaaatta aatgtaggat ttgatgatga attttataag tcaatagtat attttccact
   105781 tgtaggtttt gtcataggta tattatccta tttagtagga tggatttcta tgcttttatt
   105841 tgaaccattt atagcttcta taataataac tctagctggc gtcttaatta ctggaggact
   105901 tcatatagat ggattaggag atacatttga tgcaatatat agttatagga ataaagaaaa
   105961 aatgcttgaa ataatgaaag attcaagatt aggtacaaat tcacttctag caattatgtt
   106021 tgtactttta ttaaagattg gattcatcta cgatataata agtaataatt cattgtgggt
   106081 tataattttt atgccaatga ttgcaagatt aggagtaatg ttattgacat ataaaactgt
   106141 gacaccaagg gaaaaaggaa tgggaaattt atttatagga aaattaacta caagtatgtt
   106201 aataactgct ataatataca cattactgat agttgctctt attactaaat ttatattttt
   106261 attacctaat atagtgttga ttaaagtatt aggttcaact atagtagttt ttgtatttat
   106321 aatattattc aaaaaacata tttataaaaa aattgacgga gtaacaggag atatattagg
   106381 ttgtggaata gaactttcag aggttgtata tttaatttac atatatttgt taaattttat
   106441 gtttttttaa agtaaaaagt ggtgataata tgataagatt aatattaata agacatgcac
   106501 taacaaatga taataaaaaa ggaaaattat caggtcatat aaatagttgt attagtgaag
   106561 aaggtaaact acaaataaat aaaattacta gatatctgag taacgaaaac atagataaga
   106621 tttatacaac accatctaca cgtactaaag atacaataga aaaaatatca aaattgaaat
   106681 tattagaaat agaagaaaaa gaaactttaa gagaaattag ttttggagat tttgaaggaa
   106741 taacttttga agaaattaaa atcaaatatc ccaatgagtt tgaaaaaatg ataaaagaag
   106801 gtaacaacta taggtatcca aatggagaaa gtttgataga ctcttataaa agagtggcaa
   106861 aagaaattga taatataatt ttagaaaatg atagtaattt aggttcaaag acaatactta
   106921 tatgttctca tgcaggaaca ataagaaata taataacaca tttgatttct ggtagctata
   106981 agtatcattg gaactttaaa attgataatg cgtctattac agttttagat gttgatagtg
   107041 gatttactgt aatagataaa atgaatttta cagacttcat ataatttaat caaaatcaaa
   107101 tattacaatc tgtgtttgta atatatctgt aaaattagca atgaaaatag aatattagat
   107161 taaaattagg ttcttaatta gatgttaaaa gggaaaaagg ttagatgcct ttgcagcccc
   107221 cgctactgtg aaaccaacga aactataaat accactgtca gtttgatggg aaggttatag
   107281 aagtaggatg aagttaagcc aggatacctg cctaatttaa tttaaaacaa gaggtcttcg
   107341 gggtgaaaga tttttaatta atatatataa aagtcctatc tttagaagca ttaggacttt
   107401 ttttaatttg gtttttagta aattttaaca aggagggatg gaaagtgggg aaaaaaataa
   107461 tgctacaagg aacagcttca aatgtgggta aaagtgtctt agtagcaggt ttgtgtagaa
   107521 tatttaaaca agatggttat actgttgcgc cttttaagtc acaaaatatg gctttaaatt
   107581 cttttataac taaagaagga ttagaaatgg gaagagcgca agtatttcaa gcagaggctg
   107641 cgaaaataga gccaatagct gatatgaatc cagttttatt aaaaccttct ggaaataata
   107701 aaagtcaagt tattgtaaga ggtaaagttg taggagaaat gccttcttct aagtatcatg
   107761 attataaact ggagttagta gatgtattga aggaaacctt taatagctta aattcaaggt
   107821 atgatattgt ggttatggaa ggtgcaggaa gtaatgcaga gataaaccta aaagacagag
   107881 atatctctaa tatgggtatg gcagaaatag ctgatgcacc tgtaataata gtcggagata
   107941 ttgatagagg aggtgtgttt gcctcattag caggaacaat gcttttatta aatgaagatg
   108001 agaaaagaag agtaaaaggt gtaataatca ataaattcag aggtaaaaaa gagcttttac
   108061 aagatggtgt aaagatgcta gaagacatca taaaagtacc tgtcatagga gtagtacctt
   108121 atacagatat aaaaatagaa gatgaagata gtgtaactac tagatttaag aaaaaaatga
   108181 ataaaagcga tatacacata gaaataatta gaactccaca tatgtcaaat tttacagatt
   108241 ttaatatatt tgagacacaa gaagatgtaa gtattagata tgtagactat ggagaatctt
   108301 taggaaatcc agatatatta ataatacctg gaactaaaag tactatagac gatttaacat
   108361 atataagaaa aagtggtctt gaatcgcaaa tcaaaaattt acatagtcaa ggtaaattaa
   108421 tatttgggat atgtggtgga taccaaatgt taggtaaaaa attaaaagac ccttatcatg
   108481 ttgaaagtga aattgaagaa gttgatggaa taggtctttt agatacagaa acaacgtttg
   108541 agaaagaaaa gactacaaca caagtagaag ccactattgt tgaatgtatc agtgaatata
   108601 tgaataacct taaaggaaag aaaataaaag gttatgaaat tcatatgggc attacaaagc
   108661 gaggtaatga tgtaaggagt ttagatttaa taactaaaaa acttgataaa gaagtgaatt
   108721 atactgaagg aagtgtaaat aaagagggga atgtaattgg gacttatctt catggaatat
   108781 ttgatgaaat aagttttaca agagcaattt taaacaatat aagaaagaaa aaaggtttag
   108841 gagaattaga aagcaaagta aactctttta atgaatttaa agataaagag tatgataagt
   108901 tggctgattt tttaagagaa catttagata tagagaaaat atatgaaatt atgaaataat
   108961 gataaccttt atttataatt taggtaggag gtgtattatg aaaaaaattt taattgcggg
   109021 tactagtagt ggagtaggta aaacaacaat atcattagga ataatgcaag ctttggttaa
   109081 gagaaatatg aaagtacagc catataaagt agggccagac tatatagacc cttcatatca
   109141 cacttttata actggaagac attccagaaa tttagattct tatatgttag atgatgaaaa
   109201 aataaagtat atagtaaata agtcctcaaa agatgcagat atttcagtaa tagaaggtgt
   109261 tatgggctta tatgatggtt ttggaataga tttagataat tgtacaagtt cacatacttc
   109321 aaaggtatta aagtcacctg ttatattagt tataaatggt aaatctatgg cagcatctag
   109381 tgctgctatg gtacttgggt atagggaact agataaagat gtaaatataa aaggtgttat
   109441 agtaaataat gtaaagacta atagccatta tcaaataatt aagagttcta tagaaaaata
   109501 ttgtaatgtt gaagtattgg ggtattttcc tccaaataat aaattctctt tagaatctcg
   109561 acatctagga ttagttccta gtgtagaaat gaaatcacta agggaaaaat tttatacttt
   109621 agcagatgaa attgagcact atatagatat tgatagaata attgaaatat cagaaagtga
   109681 tgaatttgag agtgattttg attttcaaac tttgatagaa aataataaaa taaaagaaca
   109741 tgttaataat aaatcaatag ctatagcata tgataaagca ttcaactttt attatagaga
   109801 aaatatagag cttttagaag aacttggttt agaaataaac tattttagcc ctcttgaaga
   109861 tgaatcagtg ccaaatgcag attatattta tattggagga ggttttccag aaatatttgg
   109921 aaaagaatta gaagcaaacg agtcaatgag agtttctata ttagaagcac ataacaataa
   109981 tatacctatt tatgcagaat gtggaggact gatgtaccta ggtgagaaac tattgaatca
   110041 agaagaacaa gaatttaata tggttggtat attcagtgga attagcaaga tgacatcttc
   110101 tttaaagaga tttgggtatt gcattggtgt agccaaggaa aatactcttt tatctaaaaa
   110161 aggggaatct attaaaggtc atgagtttca tcattcaata tttgaaagtg atgaaaaatg
   110221 tgtgtattca atgagaaaag aacgagatgg aaatatagta gaagagtggg atggtggtta
   110281 tagtaaagga aacactttgg ctacatatct tcatactcat ttttataata acttaaattg
   110341 tatagaaaat tttttgaaca aaggaaatga gtaaatgaat attttatcta tttatatagg
   110401 gtatgtgaca gacttaatta taggagaccc atattctttt cctcatccag tgagatttat
   110461 tggtaaactt ataaatttta ctcaaggtat aataagaaag gtctctaaaa atgataggca
   110521 gttaaaattg ggtggattta tattatggtt tataactgtt ggaataacat atttaacaac
   110581 ttatgctata gtgaagctat ttagttttaa tatattattg agtattgtag tgaatagttt
   110641 tataatttat acaacactag ccacaaaatg tttaaaagat gaagcattaa aaatctataa
   110701 tgtattaaaa actgaagata tagagaaatc taggattcag ctatcttata tagtaggtag
   110761 ggataccact aatttaagtg aacctgagat aataagagca actgtagaaa ctgttgcgga
   110821 aaatactgta gatggtataa ttgcacctat gttttatgcg tttattggag gagcaccact
   110881 tgctatggcc tataaagcta taaatacatt ggattcaaca gttggatata aaaataaaaa
   110941 gtataaagat attggttttg catctgctaa gattgatgat atagccaatt atataccagc
   111001 tagaatatct gttattctta tgacaattgg aagtttcttt ttaagttatg atcatagaaa
   111061 ctgttttaaa atttctatta gagatagaaa gaatcataaa agtccaaatt gtgctttttc
   111121 agagggtgca gtatctggtg ctctagggat acaactggga ggtaccaacg tttattttgg
   111181 ggaaaaggta tataaaccaa caatagggga taagcttagg gagatagata aagaagatat
   111241 aattaaaact aataaaatta tgtatgcatc ttcatttgta tctatgttgg tatttacact
   111301 aatatatgtg ttatgtagga tgattttaat caacttaatt atataaatta ttgtttgtta
   111361 acttaagggg gacatagatg aaggatttag ggcatggagc caatgtagat gaaatggcaa
   111421 gattatatgg gaaagaccca aaagaaataa ttgattttag ctcaaatata aatccaaatg
   111481 tattaccaaa tttagaaaga tacattttaa aaggattaga agagtgtagg aattatccgg
   111541 atataaatta tacaaacttg agaaaaaata tatcaaaata tatagatata aatccagact
   111601 ttataatacc tggaaatggt gcaacagaag tgatttattt gcttatgaag agtattaaaa
   111661 aaagattggc tataataaat ccgacttttt cagagtatag aagaagtgct aagttaaata
   111721 atttagatat tatagattta gagttagaaa gtaactttaa acttaatata gatataataa
   111781 aagaaaatat agaaagattt gatagtttat ttatatgtaa tcctaataat cctagtggta
   111841 atgtccaaga tttaaaggaa cttgttaact tgctaggtaa acataataag gtactaataa
   111901 ttgatgaaac tttcatggaa tttgttgaag atgaaagtaa acatagtttg gttaaatata
   111961 tagaatcaaa taaaaatata ttcataatta aagctgtgac taaatttttt ggtatgcctg
   112021 gtttaagatt aggatatggt cttacaagta atgctgaaat tatgaacaaa atttatgaat
   112081 acaaagagcc atggactatt aattcttttg cagatatact atccaatttt atttttgaag
   112141 atagagagta tattaaagat agtaaagaat attacataaa agaaagaagc tatatgttac
   112201 aagagttgag aaacataaga aatataaagg tttatgatac agatgccaat tttattttga
   112261 taagaacata taaaaaaaca gctaaagaat tgaaaaaaga tttgttcaag caaggaaaca
   112321 tattagttag agatgcgtct aattttatag gattagatga tagttttata agagtggcta
   112381 taaaatctca taaagataac aaaattctta tagaaaatat gaaaaattta ttgggtgatt
   112441 aaaatgaaat cttatggaat atgcccagca tcttgtggag aatttgtaca aggtataatt
   112501 gatgatgaag aatatttatg ttcatatgca atagatatgt attctaaagt gtatattgaa
   112561 gaaaaattag tagatataaa tttagggagg tataagtcaa ggttagcaat tgaaaaggta
   112621 tttgaaaaat ttaatttacc taaaaaagat actaaaaata tttctttaaa tataaatagt
   112681 aaaatacctg ttggaaaagg aatggcaagt tcaactgctg atataggagc taccataaag
   112741 gcaacattat cattgataga taaagattta agtagtgaag agatttctaa attggccgca
   112801 gaaatagaac caacagattc tatatttata gataaaaaca gtatatttaa tcctctaaat
   112861 gggactgtta taaaatacct aggaaatctg accaatgcta aagttataat acttgaacca
   112921 aacaaagtac tagatactat gaaaattagg ttgaggcaag attatagtag attaaaaaca
   112981 gaaaataaag aagtcataaa aaaatcattt gctcttttag aagaaggatt gaaaaaaaat
   113041 aatttatctc tagttggaga ggcttgtact ttaagtagct tagcaaatga gaatatagac
   113101 aaaaaagagt atttaaatga aataataaaa atatcaaaaa aatatggagc atatggagta
   113161 aatattgctc atagtggaac tgtagtaggt attttaattg ataagttcat gaatgataaa
   113221 aatatgatag atgccttgtg tgaatctaac ataaattctg tctatagtaa aatttataca
   113281 ctaaacataa ttaatggagg aattaagggg gaaatagaat ggaatacata aagaatccta
   113341 tgaaaataga agaaaaaagt tttgaattga tacaagaaat aatagacgaa attagaccag
   113401 attataaatt taagaataat atcgaagaaa aaataataaa gagagctata catactactg
   113461 cagattttga ttacttagat atattaaaaa tatcagaaga agcagttgcg agtataatag
   113521 atgcattaag aaataatgca agtatttata ctgatactaa tatggctctt agtggtataa
   113581 ataaaagaaa gttagaatca ttaggatgta agtataaatg tttagtggca gatgatgaaa
   113641 ctgtaaaatt agctaaagaa agaggaatta ctcgttctat ggcagcggta gaaattgcag
   113701 ctaaagaaga aggaagaaaa atattcgttt taggcaatgc accaacagct ttatataaag
   113761 ttatggagat gaaatcagaa ggtagattag atttagatgc agttatagga gttcctgtag
   113821 gttttgtagg agcagaagaa tcaaaagatg aagttgaaaa aacagatata ccatatataa
   113881 tttctaaagg tagaaaaggt ggcagtaatt tagcagcagc aatagtaaat gctatattat
   113941 atactatgta ggtacatata tggaagaata tgtatatata gatggtaaaa aatatagaag
   114001 aggatatact acaggttcat gtgcaacagg tgcatctaag gctgctgtat atatgttgat
   114061 tacaaaaaat agaatcaata ctataaatat agacactcct aaaggaatac cattatcact
   114121 aaaagttgat aatataaata tttctgatac atttgtggaa tgttcaataa aaaaagatgg
   114181 tggagatgat atagatgcaa ctcataccat ggatatttat gcaagagctg aaattgtatc
   114241 taaaaatgat aagaacaaag agtatcttac tctaaaggat atagatggtt taagtaacaa
   114301 tagtgaatcc caaagtgaac tctataagtt tattcgggtt tatggtggaa ttggtattgg
   114361 tgtggttacg aaaaaagggc ttagtgtaga tgttggtaag cctgctataa atccgactcc
   114421 tcttaaaatg ataaatcatg aaataagaaa tcttatagga gataattttg aatctatact
   114481 tggaaataat aaagttttaa aaataacaat ctttgctcca caaggagaag ctgtagcaaa
   114541 aaaaacattt aatccaagat taggtatagt tggagggata tctataatag gtacaactgg
   114601 gattgttgaa cccatgagtg atgagggctg gaagaagtct ctatctatag aacttcaaat
   114661 gaaaaaagaa caaggtttag ataaaataat attggttcca ggaaatcatg gagaacagtt
   114721 tataagagaa aaattaaatt tagatattaa gtatgtagtt aggacaagta atttcatagg
   114781 ttatatgatt aaagaagctc aaagaatagg atataaaaaa atcttaatgg caggtcatat
   114841 aggtaaattt ataaaaatat ctgctggtat ttttaatact catagtaagg tggcagatgc
   114901 tagaagtgag atattagtgg caaacttagc tttaatggga gctacatacg aatttttaaa
   114961 taaaataaat caatgcctaa ctactgaaga agctgtagaa ttaataaata atagtgagta
   115021 tagacaagtg tataatatat tgagtaataa atgcagggag agagtaaagc aatacttgaa
   115081 tgaagattca gatgatattg atgtagaagt aatcatattt tcaatggata agtctttatt
   115141 aggtaaatcg gataatacag atgatttagt ggaggtcttt atatgataaa cataataggt
   115201 ctaggacctg gtaacttaga ctatataaca aaaaaaggtg aaaatttaat ttccacttct
   115261 gatgtattaa ttggtggtaa gagaaattta gagtctataa aaaactttga aggagaaaaa
   115321 atagtcttag attctaattt aagagaaatt atagagtaca taaataacaa taaagaaaag
   115381 caaatatcaa taatagcatc tggtgaccca ttaatatatg ggataggtag atatatatct
   115441 aaaaatattg ataataagat gctaaatatg gtttctggga ttagttcatt acagtacata
   115501 ttttcaaaaa tatatgttga tatgaatgat gtatatatta caagtagcca tggtaaagta
   115561 ccagattttg attacatatt atcacataaa aaagtatgta tggttacaga ctctaagata
   115621 ggaccaaaac aaataagtag agaagtaata gatagaaatc taaataaaat tattgttgta
   115681 ggagaaaatt tgtcatatga caatgaaaaa ataacaatag caaaaccaga agagataata
   115741 agaatggaca attttgatat gaatgttgtg gtgattttag atgaggaata gtgaatttgt
   115801 aacaggtaaa gttccaatta ctaaggaaga agttagagca atatcaataa gcaagttaaa
   115861 cttagtaaat gctaaaaact tcatagacat aggagctgga acaggaagtg taagtgttga
   115921 agctgcatat aattatccta atttaaaggt tatatctata gagaaaaatg atgatgctat
   115981 agagcttata gagaaaaata taaggaagtt taatttaaaa aatatagaag tgataaaagg
   116041 atatgctcca attaacctag gattaaatac taaagttgag tctatttttc ttgggggaac
   116101 aggaaataat ctggaagaaa taatagaatg gtctaaaaaa aatttggttg taggaggaag
   116161 acttgtagct aattttataa taatagatac atttaatcaa actttaaaac tgcttaaaaa
   116221 gcatggattt aaagaaatag atgtatgtgt tttgaatgtt tctaaactag agaaactagg
   116281 aaaaggtgaa tactttaaac cactaaatcc tatatatata atatcttgtg aaaaagggga
   116341 aaatgatgat gaataaagta cattttgtag gagcaggacc tggagataaa gagttgataa
   116401 cattaaaagg atataaatta ttaagtgatg cagatgtagt gatatatgca ggttcacttg
   116461 ttaatcctga acttttggaa tactgtaaag aagattgcca aatacataat agtgcacata
   116521 tggatttaca agagataata gatgttatga gagaaggtat agaaaataat aagtctgttg
   116581 taagactgca aacaggtgat ttttctatat atggttcaat tagagagcaa gtggaagatt
   116641 tgaataaatt gaatatagat tatgactgta ctccaggagt aagttctttt ttaggtgcag
   116701 catcatcttt aggagttgaa tatacagttc cagaaatttc tcaaagtgta attataacaa
   116761 gaatggaagg tagaactcca gttccagaaa aagaatcaat acaatcatat gctaagcatc
   116821 aaacatctat ggtaatattt ttatctgttc aagaaattga gaaagttgtg tctagattgc
   116881 tggaaggtgg atatccaaaa gatactccta tagcagttat atacaaagca acttgggcag
   116941 atgaaaaaat agttaaagga actttaagtg atatagctgt aaaagttaaa gaaaacaaca
   117001 taaataagac cgctttaata atggttggaa gatttttagg agaagagtat aataattcaa
   117061 agttatatga taaggatttc aaacatgaat atagagggta atattgctat aatctgtatc
   117121 acagaaaatg ggaaaaaatt agctgtaaag ataaattctc tagtaaataa ctgtgttata
   117181 tatcaaataa aaaataaaaa aagcaattta aatgttgaag aaacgtgtgt acatacagtt
   117241 caaaagaaat taagtgattt tgtaggagaa atatttaata aatttgatta catagtattt
   117301 ataatggcta caggtatagt tgtacgaagt atagcaccat acataataag taagtttagc
   117361 gaccctgcag ttttggtaat ggatgaaaaa ggcgaaaacg taataagttt attgagtggg
   117421 catattggag gggcaaacag tttgacacag tacataagta gtcttattga tgctaatcca
   117481 gtaataacaa cagctactga tgtaaatcaa aaagcttctt tagatatgat agcaaaaaaa
   117541 ctaaatgcat atattgatac ttttagagaa agtgtaaaag aagtaaattc tatgctagtg
   117601 aacaataaat gtgttggatt atatattgat gaaggatatc aagttgatac tagaggattt
   117661 aaacttctag aaagtaagga tgagttaaga gatagttttt caaatatata tatagaaaaa
   117721 ttagttgtag taagcaataa aataaattgt attgaagata ttgagaattt aaacttagat
   117781 aataaatttg aactttacta tagtactgaa aaaataataa aagtaattcc aaaagatata
   117841 gtaataggaa ttggatgtag aagaaacaca gatagtgagt tgatgtataa ttcacttaaa
   117901 gagtttctta ataaacaaaa tatagatatt agagcaataa atacagttgg aagtatagaa
   117961 ctgaaaaaag acgaaaaagc aataattgaa ttatcaaaaa cactaaaagt gccatttaag
   118021 acattttcaa tagatgaaat atctaaggtt gataatcttt ttgataaatc tgattttgtt
   118081 aaaaaaaatg tgggcgtgta ttcagtagca gagcctgtag catatctttt gagcaaaggt
   118141 aatttgttag ttgaaaaaca taaatataaa ggaataactt tttcagtggg gagaataaaa
   118201 atatgatata cgttgtagga attggaccag gaagtaaaga tacaatgact ttagaagcaa
   118261 taaaagcaat agaagattct gaggctattg ttggatataa gacttatata aaattaatag
   118321 aagaatttat acaagataaa gaaataatcc aaaatggtat gaggcaagaa gttgatagat
   118381 gtaaacaagc agtagcggaa gcaaaaaaag gaaaaaaagt agcagttgta agcagtggtg
   118441 atgctggaat atatgggatg gcaggtctta ttttagaatt aatatctaaa gaagatgaag
   118501 atataaaagt aaaggtaatt ccaggtgtta ctgcaagtat tggtgcagca gctatactcg
   118561 gagctcctat tatgcatgat ttttgtcaca taagcttgag tgatttaatg actccgtggg
   118621 aagtaattga aaaacgattg agattagctg ctgaagctga ttttgtaatt tgtttgtata
   118681 atccaagaag taagggaaga agtgaacatc taagcaaagc atttaaaata atgggtgagt
   118741 ttaaagatgg agatacacct gttggagtgg taaaagatgt aggtagagaa aaagaagaaa
   118801 agtttgtatg tacttttgaa aatatggact ttgaaaaagt cgatatgact acaatggtta
   118861 taataggaaa taaatctact tatattgatg gtgaattgat gataactcca agaggttata
   118921 cagtatgatt ttaattttag gaggaacttc agatagttta tctatatgtg ataagataaa
   118981 tgaactgaaa aaccaaccat atattctttc agtgactaca gattatggaa gggaacttgc
   119041 acaacaacat gcaaataatg taattttagg taagcttgga aaagaagata tgttaaaatt
   119101 tataaaggat aataatatag taaaaataat agatgccact catccttatg cagttgaagt
   119161 atccaaaaat gctattactt gtgcaaaatt atcgaatata gattatataa gatttgagag
   119221 aaaatcttta attgatgaaa tagattatga taataaattt atagtgaata caatcgaaga
   119281 agcctgtgaa atagcaaata aaatagggac aaatatattc ataggaacag gaagtaaaaa
   119341 tttgaacagg tttatagagg aaataagtga taaaaattta gttgtgagag ttcttccaac
   119401 tagtgaagtc atattaagtt gtgaaaaatt aggtttaagt gcagacaata taatagctat
   119461 gaaaggtccg tttagccagt atataaatga agaaacatat aaacattaca atatagattt
   119521 agttataaca aaagaaagtg gaatagctgg tggattctta gagaaggtaa atgcatgtaa
   119581 aactttcaat ataccagtaa taattataaa aagagaatca attaactacg aaaatgtatt
   119641 taatgacata aataaaatta aagacatact tgtgtaattt ttaggaggag aatatatgaa
   119701 gaaagcctta ttagtagtga gttttggtac aagctatcat gaaacgagag aaaagacaat
   119761 agatatatgt gaagataaaa taaaaaattc attaaaaagt tatgattttt ttagagcata
   119821 tacatcaaat atgataataa ataaaataaa aaaaagagat ggaatagaaa tagataatcc
   119881 aatacaagct ttagataaaa tatatgagca aggatatgat gaagtaataa tccaaacact
   119941 tcatattata tgtggcgaag aatttaacaa attaaaagag caagtagatg gctattcttc
   120001 caaattcaaa aagattgtat taggaagacc tttacttaca catattgaag attatcagga
   120061 agctgtagag gcaattaagc atcaaattcc tcatatggaa agtgatgaag cagtagtatt
   120121 tatgggacac ggaacacttc atgaatcaca ttcagcgtat cctgcattag aatacatgct
   120181 tagagacaat ggagtaaatg cttatgttgg tacagttgaa gggtatccag aaatagaaca
   120241 tgtaataaga agactgaaag aaggaaatat aaaaactgta aatttgatgc catttatgtt
   120301 agttgcagga gaccatgcta taaatgatat ggcaggagat gaagaagatt cttggaaaac
   120361 aatattagaa gaagatggat ttaatgtaag agttcattta aaagggctag gagaaaattc
   120421 ctatatacaa gataaatttg ttcgtcatgc tttaaaatgt gcagagaatg ctaagtttta
   120481 tggtatagga gcgggtccgg gagatggttc tttacttaca ataaaagcag ttaatacttt
   120541 aaagaaattg gatattctat acactccaga atcaaaaaag ggtggagata gtctagcttt
   120601 atcaatagtt agtgaatact tacctgaatc agtggaaata aaatctaggc attttccaat
   120661 gagttttgat gggaatgaaa aaagtttagc ttgggataat gtggcacaag aaattatatc
   120721 agatgttaat gatggtaaaa atgtaggatt tgttacatta ggagacccta tgatttatag
   120781 cacgtatgta tatataatga aaagaatatt aggagaggta gaagtcgaaa ctataccagg
   120841 aatttcatca ttttcgaata tagcatctaa tcaaaatttt ccattagtta tggacaaaga
   120901 agcattagtg gtaattcctt gtactatgga agatgataaa atagagtatg ctttgcaaaa
   120961 ttataactca atagtattga tgaaggtata taaaaatttc aaagaaataa taaaaaaatt
   121021 agaaaagtat gatttaatag aacatgctat tttagtaagt aattcttccc aagaaagcga
   121081 aaatgtattt acagatttaa aagaagcgca ccttgaagat aagatatctt atttttctac
   121141 tatactagta aataaagata ataaaataaa ataggtgaaa gcaatattta aaggagattt
   121201 aatatgaata tagtggttgg aactaggggt agtaatctag cacttataca aacagaatgg
   121261 gtaataaatg aattgaaaaa gaagtatcca gaaattagtt ttgagattaa aatcataaag
   121321 acaaaaggag atttaattca aaatgtatca cttgataaaa taggtgataa aggattgttt
   121381 gttaaagaaa tagagcaaca attattgtat ggaaaaatag acatagcagt acatagtatg
   121441 aaagatatgc cttcttattt agcagatgga ttaaaatttg ctcatacgcc taagagagaa
   121501 gacccaagag atgttctaat acttagggaa ggatataaaa atttagatga tttgcctcgt
   121561 ggagcagtaa taggaacagg aagcaaaaga agaaagtttc aattattgaa acaaagacct
   121621 gatttaaata tagtacaagt tagaggtaat gtggaaacta ggataagaaa aataaaagat
   121681 gaaaatatgc atggtattgt gttggcagca tcaggaataa ttagagctaa tttacaagat
   121741 aaaataagtt cttatttacc tgttgatgtt gttattccag cacctgccca aggagcctta
   121801 gctatagaaa ttagaagtaa cgatagtaag atagagggaa tagtaaattc actgaaagat
   121861 gagaatacag aaattcaaat attggctgaa agaggttttt tagatggtgt aaatggaagt
   121921 tgtcatattc caatggcagc ttattgtgaa ataatccaag ataaaataca tcttactgga
   121981 ttatatggag attcagaagg aaaaaaagta gtaatcaagt ctatagatgg agatatttct
   122041 tctcctagag agttaggttt aaagttagct aaacttgtgt tgaaggagta tgagaattat
   122101 gaagggtaag gtttacttag taggggcagg accaggtgat tataaactca tgactttaaa
   122161 gggtttagag tgtataagaa aatcggatgt aatagtatat gatagattag caaatagtaa
   122221 ttatttaaga gaagctaagc ctgattgtga atttatatat gtaggaaagg catcgagtaa
   122281 tcatattttg ccacaagaag atataaatag aattatagca gaaaaagcta aagaaggaaa
   122341 aattgtaact cgtcttaaag ggggagaccc ttatgtattt ggtagagggg gagaagaagc
   122401 agagacttta gtagatgaag gtatagaatt tgaagtagtt cctggtataa cttctgcaat
   122461 aggaggttta tgttatgcgg gtattcctat aacacataga gaccatgctt cgtcatttca
   122521 tgtaataaca ggtcatctga agggtgatga tagtggagaa ttaaactgga atgctcttgc
   122581 aaataataaa ggtactcttg tgtttttgat gggaatctca aacctaaata aaataagtga
   122641 aaacttaatg aaagaaggta aagataagaa tacacctgtt gctcttataa gttgggcaac
   122701 tagatataat caaagagttg ttacatctac acttgaaaat gtttatgaaa ctgctattaa
   122761 agaagaggta aaaccgccaa ctcttatagt agttggaagt gttgtagaac ttagagaaaa
   122821 gttgaatttc tttgaaagta aacctttatt tggaaaaagt attgctgtaa ctaggtctag
   122881 aaatcagaat agtgtattag tagaaaaaat aatggattta ggtggaaatc caatagaaat
   122941 acctactatt aaggtagaaa aaatacaaaa caatattaaa ttagaaaatg aaataaaaaa
   123001 tataaataag tataattatc taatactaac tagtaaaaat gccgtagaaa ttttctttga
   123061 aaagatatat gaaatgaatt ttgatttaag aatactatct aatttaaagg tatgtgctat
   123121 aggttctgct acatcaaacg agttgaaaaa gagaggaatt atagcagata tagtacctaa
   123181 aaaatttgtg gcagaatcac tgtatgaaga gttaatgcct attttaaata atagtgataa
   123241 tatacttata cctagagcag aaaatgctag agattatctg gttgacaaac ttaaggccat
   123301 ttgtgaagta acagaagtac atatatatag aacagtaata gatgaggata aaaaagatga
   123361 gatattagat attttaaatt ctaataatat agattatata acatttacta gttcctcaac
   123421 agtaaataat ctcgttgaaa ttataggaaa agaaaatatt aaaatattag aaaaaataaa
   123481 aacattatct atagggccta taactacaga tacaataaat agtttgggaa taaaattgta
   123541 caaagaatct gctacatcta ctatagattc gttagtagat ttaattataa aaaattaatt
   123601 ttggaggctt gaatatgtta agaagaccaa gaagactaag agcaagtaaa gcaatcagaa
   123661 atttggtaag agaaactaaa gtgaatgtag aagatttaat atatccactg tttgtagtag
   123721 agggggaaaa tataaaagaa gaaattaaat ctttaccaga tgtctatcat ttatcaatag
   123781 acatgttaga agaagaaata aaagaaataa gtgagttggg aattgaacat ataatgttat
   123841 ttggtgttcc agatgaaaaa gatgagtgtg cttcacaagc ttttaatgat aatggaatag
   123901 ttcaaaaggc aattagaaag gtaaaagaaa taaatgcaga tatgaatgta ataacagatg
   123961 tctgtatgtg ccaatataca agtcatggac attgtgggat tttaactgat actggttatg
   124021 ttgataatga taaatcatta gagtatctag ctaaaatatc tgtaagccat gctaaagcag
   124081 gagccaatat ggttgctcca tctgatatga tggatggaag aatacaagca ataagagaag
   124141 ctttagatga aaatggatta gaaaatgttg gaattatggc ttatagtgtt aagtatgctt
   124201 caaattatta tggacctttt agagaagcag ctcactcagc accatctttt ggagatagaa
   124261 aaacatatca aatggatcca gcaaatagta atgaagctat aatagagact gaacttgata
   124321 tattagaagg tgcagatata cttatggtta aacctgcatt atcatattta gatattataa
   124381 gaagggttaa agataatttt gatttacctc tagcagctta taatgtaagt ggagaatact
   124441 ctatgcttaa gtttgctgtg aaggaaggtt tattaaatga agatgtaatt cttgaatcaa
   124501 ttacatctat aaaaagagca ggagcagata taataataac ttattttgct aaggatattg
   124561 ccaagttatt aaaaaataaa ttttagctag aaaaagaatt ttaaaaagta taggaattgt
   124621 aattagatat tatataatat ttttatttaa tttgttgaat aagaatagat actaatttat
   124681 aatttctatg ctttatttgt ataatcaaat aaagtttgga ggtataaaat gctatatcct
   124741 attaatttaa aattagatga cttagatgta gttataattg gtggaggaga agttgcatat
   124801 agaaaatgta aaaacttttt aaatttcaat aaaagagtta ctatagtttc taaacaactg
   124861 ttaaataagt tttatgattt gaaagaatac ataaatataa tagaagatga ttataaagaa
   124921 gtgtatatag aaaaagcctc tatagtaatt gctgcaacaa acaataaagt attgaatatg
   124981 gaaataggat tatattgtag agcggaacat aaattagtaa atgttgttga taatgtagaa
   125041 atatcaaatt ttactgttcc atcatatata aaaagaggcg atttacttat aagtgtatct
   125101 actggaggca agagtccttc actgtcgtca aagataaaaa aagagattga agagatatat
   125161 actgaagatt atgaggagta tttaaatgta ttaggagata taagaaaaaa ggttataaaa
   125221 aaatacgaag ataaaagtaa aagaaaagat gtgcttaaca tgttgataac acttgactta
   125281 gaagaactta agaagtttga tatataaaaa ataaaataaa aaatgttaaa aaagtgttga
   125341 cg
//
LOCUS       DAMKOJ010000002       112918 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000002 DAMKOJ010000000
VERSION     DAMKOJ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 112918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 112918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..112918
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.002"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            21..1553
                     /locus_tag="PC592_000128"
     CDS             21..1553
                     /locus_tag="PC592_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009260080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HDF4054159.1"
                     /translation="METQRTILQQYAKEQGLHVVGEYVDDGWSGTNFERPDFQRMMDD
                     MEAGKVNCIVTKDLSRFGREHVMMDYYLEFLFPEKRVRYIAVAENEDTEKGLSDFVPF
                     KNLFNEWFAKDTSRKVKAAFKAKFATGQRIGAYAPIGYRKHPEIKNKLIIDEETRWIV
                     EKIFDLAIHGRGAASITRILIAEKVPTPGFINFQRDGTFANIYAGAPEEKSYAWTIAQ
                     VKSIMKDETYIGHTIHYRETNISFKNKRRVRKPQSEWVRVENTQEPIISEQVFRQVQE
                     QIANRRRKCKDGTTQIFSGLVKCADCGWSLSYGENRQNSKPYGHYHCSKYGQGTRQCS
                     MHYIRYDVLYAYVLSRLQYWSGLVQHDEERLLKQLLNATDKGQAAARKKQAAELKKAE
                     KRKAEVDTLFARTYEDWAAGRITEYNFSMLSGKYQSEQAELDEKIEQLQSAIATESQN
                     AVDAEKWIALMKECVNPTELTAELLNMLIEKIVVHEAVKGEDGSREQEVEIFYRFIGK
                     ID"
     gene            1639..2088
                     /locus_tag="PC592_000129"
     CDS             1639..2088
                     /locus_tag="PC592_000129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF4054160.1"
                     /translation="MTIDELLSGEKLLSIAEKENKANLQRMCSLLFGIVDLFSFMLIV
                     LPLYPNPINGYIYSVNLFSYTDTAFFNIILYWVSYLALIVMGITKIALTQLKTERGQS
                     IITSLSLGLSILTVLYLGMAREAYAITVAFMLLLIKGILLLKYTQNS"
     gene            2204..3799
                     /locus_tag="PC592_000130"
     CDS             2204..3799
                     /locus_tag="PC592_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006859284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HDF4054161.1"
                     /translation="MPIPHLNIRIVQRSKGSSAVAGAAYQAGEKLFSEYDQKNKDHRR
                     KQKEVVYTEIMLPANAPPEYADRETLWNSAEEVEKQWNSQLARRFVVALPREVPLEMC
                     PQMLQEYCEEYFVSKGMCCDIAIHDPDPPGHNPHCHIMLTMRAIDENGKWMPKSRKVY
                     DLDENGERIKLPSGRWKSHKEDTVDWNEQYHAEEWRHGWEVIQNKYLELAGSPERVDM
                     RSYARQGIDVIPTVHMGAAVSAMERKGIETNIGNLNRDIKSANSLMAAIRKTIKSLLE
                     WIADVSEATKEALAEMKEQNASPTLAGLLNEYLNVRKEERRDWSRYGQNKGSLADVQA
                     VSKAVAYLRDHNLYTLKDLDEALQEVNGRAASIRSAIKTAETRMKTITQIQKAVSVCK
                     EHKAVKDKYLKIGWKAAQAVYAETHKDALSAFDKSFRYLKKQGLDLRVDLTALQSEFD
                     TLEKSVAENNAKLSEVKAELQPLKDVRYWISKVIEPEQGEVEKKPEPKHSVTEKMKYL
                     QEQKKQLEPKSPQHKQKKQNMEL"
     gene            3868..4485
                     /locus_tag="PC592_000131"
     CDS             3868..4485
                     /locus_tag="PC592_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009259716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF4054162.1"
                     /translation="MNVFEAVKPNISTRQAAEMYGIKVNRNGMAVCPFHNDKNPSMKV
                     DKRFHCFACQADGDVIDFVSRLCGLPCKEAAMKLADDFGISYDSRHKPTVRPHIREPT
                     AEQLYQKEEARCYRVLTDYFHLLRRWETQHAPKQPDDVWHPLFVEALQRKSHIEYLID
                     TLIDGTKEEKQALVAEQRKEVMKLEQRIAEYRGRSPKQFGAEPER"
     gene            4418..5767
                     /locus_tag="PC592_000132"
     CDS             4418..5767
                     /locus_tag="PC592_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006573536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HDF4054163.1"
                     /translation="MNNELQNTVDEVRNSLEQSQKGKVYNTAANYKRVLQCDPLLKGA
                     IRKNLLTERIDIVKPLGWYRDSTTLTDVDIKYLVLYFEENYGLTVEKKIVDAITVIAN
                     ENRYHPVCDFLNSLKWDGQERIRHCLHHFLGSEENEYTYEALKLFMLGAISRVFKPGC
                     KFEVMLCLVGGQGAGKSTFFRLLAVNDDWFSDDLKKLDDDNVYRKMQGHWIIEMSEMI
                     ATANAKSIEEIKSFLSRQKETYKIPYETHPADRKRQCVFGGSSNTLDFLPLDRTGNRR
                     FLPVMVCPEQAEVHILEDEATSREYIIQMWAEAMEIYRSGNFKLKLSRSTDEFLKAHQ
                     KEFMPEDTKAGQIIDYLERYSGNTVCSKQLYREALGHDYDEPKQWELREINDIMNNAV
                     TGWKAFANPRYFPEPYRRQRGWERIPIDNEPDNNTGKFHELTEAEMQQLELPKEWLE"
     gene            6021..6188
                     /locus_tag="PC592_000133"
     CDS             6021..6188
                     /locus_tag="PC592_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF4054164.1"
                     /translation="MNTNTIQTTAQHTQPCYRKTIDKTTYVVRVHFSENAKETMEDKI
                     KRLLREEVAKM"
     gene            6227..7057
                     /locus_tag="PC592_000134"
                     /pseudo
     CDS             6227..7057
                     /locus_tag="PC592_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037036.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            7299..7439
                     /locus_tag="PC592_000135"
     CDS             7299..7439
                     /locus_tag="PC592_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054165.1"
                     /translation="MAFFNSAVNVLQTLVIALGAGLGIWGVINLLEGYGNDNPGANAH
                     VR"
     gene            complement(7582..8802)
                     /gene="tet(40)"
                     /locus_tag="PC592_000136"
     CDS             complement(7582..8802)
                     /gene="tet(40)"
                     /locus_tag="PC592_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009247026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(40)"
                     /protein_id="HDF4054166.1"
                     /translation="MFAKNSKAYSVYLLFRFVFSLAVSMSTVLSIVYHLEVVQLDAFQ
                     LVLVGTVLETSCFLFEIPTGVVADLYSRRRSVLIGMFLYGLGFLMEGALPWFAPVLLA
                     QVVWGCGDTFITGALEAWIASEEEDKPIDKVFLRGSQMGQIGGVLGVVLGTLLGNINL
                     QMPVILGGSLCLLLGLVLVRIMPETNFSPAIEERQGLLKDFVCLFKLNLGFVKGAPVL
                     LALLAITLCGGLASEGFDRLSTAHFLDDTVIPVIGPLNSVTWFGVISLIGSGLGILAS
                     QLLIARMEKKGTVSRTSVVMSTSAGYILCLVLFAVGRSFWFMLLVFLLAGLMRTIKEP
                     VLAAWMNDHVDEKMRATVFSTSGQLDSFGQIIGGPIVGLVAQQVSIPWGLVCTAFLLL
                     PALFLVPVAGKKRD"
     gene            9223..9621
                     /gene="mobC"
                     /locus_tag="PC592_000137"
     CDS             9223..9621
                     /gene="mobC"
                     /locus_tag="PC592_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF4054167.1"
                     /translation="MRKKYNTPHRSRVVKTRLTEDEYADFTARLAPYGISQSEFLRQA
                     IRRTTIRPVLHVSSVNDELLSAVGKLAAEYGRIGGNLNQIARYLNEYGAPYHALSGEV
                     RAAIADLAALKYEVLKKVGDAVGNTQTYQL"
     gene            9593..11218
                     /locus_tag="PC592_000138"
     CDS             9593..11218
                     /locus_tag="PC592_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF4054168.1"
                     /translation="MATLKHINSKNADYGAAEQYLLFEHDEFTMKPVLDETGRLIPRE
                     DYRLSTLNCGGEDFAVACMRANLRYEKNQRREDVKSHHYIISFDPRDGPDNGLTVDRA
                     QALGEQFCKEHFPGHQALVCTHPDGHNHSGNIHVHIVINSLRIEEVPFLPYMDRPADT
                     KAGCKHRCTDAALRYFKSEVMEMCHREGLYQIDLLNGSKNRITDREYWAQKKGQAALD
                     KQNAPMIADGITPRQTKFETNKEKLRQTIRKALATAASFDEFSSLLLREGVTVKESRG
                     RLSYLTPDRTKPITARKLGDDFDRTAVLAVLEQNAARAIEKAAAIPEYPWQEKRGIQP
                     AKAPQTAPKQDGVQRLVDIEQKMAEGKGRGYERWAKIHNLKQAAKTLSVYQQYGFTSP
                     EQLEAAVDTAYAEMRQTSGELKALETKLQGKKELQRQVLAYAQTKPARDGLKAQKSEK
                     ARAAYRQAHESDFIIADAAARYFKAHGITKLPARKALQAEIEQLISEKDGLYNTYHEQ
                     KQRFKELQTVKRNINQILRRDEPHRRKEQSHER"
     gene            11208..11594
                     /locus_tag="PC592_000139"
     CDS             11208..11594
                     /locus_tag="PC592_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009259636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP protein"
                     /protein_id="HDF4054169.1"
                     /translation="MSDNLPRMDYRQHRRARRLVHECCNYDEGNCLLLDDGEPCVCVQ
                     SISLSLMCRWFRVAVLPLDGELSAALLYRGSRKRCAVCGAAFVPKSNRGKYCPDCAGR
                     MKKIRAAERKRKQRQRCHALEPFKPA"
     gene            11707..12123
                     /locus_tag="PC592_000140"
                     /pseudo
     CDS             11707..12123
                     /locus_tag="PC592_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605636.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
     gene            12123..13511
                     /locus_tag="PC592_000141"
                     /pseudo
     CDS             12123..13511
                     /locus_tag="PC592_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147943.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            13590..13805
                     /locus_tag="PC592_000142"
     CDS             13590..13805
                     /locus_tag="PC592_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF4054170.1"
                     /translation="MTEQNGTPTAPRNPDSIITTQRNGQTIVAELFFNHSSTETFRDK
                     LLKTILADSSCLSASDGQEPEKSEILR"
     gene            13940..14242
                     /locus_tag="PC592_000143"
     CDS             13940..14242
                     /locus_tag="PC592_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054171.1"
                     /translation="MRTGLTKQEKTTDIWFDEKDPLIHIRTHNTALKKRLLAYSRRYP
                     AICQQTDADPETGCMEFDIEKGRFSFRLTAPYSEERRAVCQREQRRRQAEIELKCS"
     gene            14411..15244
                     /locus_tag="PC592_000144"
     CDS             14411..15244
                     /locus_tag="PC592_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF4054172.1"
                     /translation="MNNNLSRFADSKVYFQCPICTKSMDIQGNSLICRHGHCFDISRY
                     GYVNLLLKSSPKTNYSKRSFDNRHQILEYGMYDVVLEKIIQFISDTPSIRNILDVGCG
                     EGFYARQIQQRTERNIFAFDLSREAIQIASKKDKRKAVKWFVTDLSKIPLKDGSMDCI
                     LDIFSPAHYKEFQRLLSPNGYVVKVIPTKNHLREIRTKVQAHLKNPDYSNESVVEYFE
                     KYLKTISRETVSATVQLSSEQRMSFIEMTPLLFCVEKDCVDWRTLTHLTIEADVLIGM
                     Y"
     gene            15366..15671
                     /locus_tag="PC592_000145"
     CDS             15366..15671
                     /locus_tag="PC592_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HDF4054173.1"
                     /translation="MTTHDETERKKREELQAEIEDGKKKIRQLENREKVLRQKLSQEE
                     RRTRSHRLIVRGAVFESIVPEAKTMTDEEAAAFLRLALTSEEARGYLKKRTEGGKSE"
     gene            15911..17425
                     /locus_tag="PC592_000146"
     CDS             15911..17425
                     /locus_tag="PC592_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005922895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HDF4054174.1"
                     /translation="MIPIAIYHCNISIVSRGKGKSAVAAAAYRSGEKLTNEWDGMTHD
                     YTRKGGVVHTEIMLPPHAPPSFSDRSTLWNSVELYEKAGNAQLAREIDAALPIELSRE
                     EQIRLVREYCSSQFVSRGMCVDYAIHDTGKGNPHCHIMLTMRPLDERGAWAAKSQKEY
                     DLDENGERIRLPSGRYKTHKVDLTGWNDKGNALLWRKAWADISNAYLERAGSPERIDH
                     RSNAERGIGEIPTVHMGVAACQMEKKGIATEKGELNRNIQKANRLIREIRAQIGKLKE
                     WIADLFKAWETAPEQPQQSPGLANLLMKYLSVQREKSRKYSQRWQQQHTADELKTIAA
                     AVNYLTEHGISTLDELDAALSSVSEQADTIRAGMKTAEERMKKLQKLIEYGKNYTEYK
                     PVHDELKKLQNGWTNKRDKYEEAHRAELTLWNAASRYLHANLPKGTKTLPIAEWEQEY
                     ADLKTQRDSDYAKLKDTRADVSELQKIRKCVDIALRADQPEQTQTRTKRHDIDR"
     gene            17440..19341
                     /locus_tag="PC592_000147"
     CDS             17440..19341
                     /locus_tag="PC592_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4054175.1"
                     /translation="MYYTQEQIDRANQADLVLFLQSQGEPLERAGQEYRWKRHDSLTV
                     RGNKWYRHSQSKGGGPIDFVMEFFGKSFTEAVELLTGEKGAAPPPDRPSSAPLSDFRL
                     PPRSPDNRTARNYLTAARRIDEDVTGFFFASGDIYEDAAHHNAVFVGRDEDGIPRYAH
                     SKGTAGNFRLDVKGSDKAFNFCYRGEGERVFVFEAPVDLLSFLCLFKKDWQKQSYLSL
                     GGVGEKALLRFLSDRPNIKTVYLCLDSDEAGNDACSRLVKLMPEGYTVHRLIPLFKDW
                     NEVLQHRAEITDGKYLREAVYGLKEPPQEETVEIIRMSEVDTQTVEWLWEPYIPFGKV
                     TIVQGNPGEGKTTFALRLAAACTNRKPFPHMAVHEPFNVIYQTAEDGLGDTIKPRLME
                     AEADLDRILVIDESKQGLSLSDERIERAIRQTGARLIILDPIQAYVGEKTDMNKANEI
                     RPMFRRLAEIAERTGCAVILIGHLNKAAGGQSAYRGLGSIDFRAAARSVLLIGRVKRE
                     PNVRVIVHDKSSLAPEGKPIAFCLDPETGFSWIGEYDITADELLSGAGGNTATKTEQA
                     ERLILDLLADGKELASEDLVKAAAEAGISERTVQNAKRNMGGVLGARRVGGQWYNFIK
                     KKQPPEPAS"
     gene            19464..19724
                     /locus_tag="PC592_000148"
                     /pseudo
     CDS             19464..19724
                     /locus_tag="PC592_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604475.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
     gene            19731..19997
                     /locus_tag="PC592_000149"
     CDS             19731..19997
                     /locus_tag="PC592_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HDF4054176.1"
                     /translation="MANTKLDRIERDIEKTRAKILEQQKKLKDLEAQKVEEENAQIVQ
                     MVKAVHLDGTQLAAFLSAYASGEITLPQPEATYPAEQEDNDNEE"
     gene            19987..20736
                     /locus_tag="PC592_000150"
     CDS             19987..20736
                     /locus_tag="PC592_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF4054177.1"
                     /translation="MKNKKIIRKFTVLLAALVIMCGFSVTAYAGGGDESDDTPTPVTE
                     ETPAPETEPEETTGGYEPQPLTPDGNMSLVDDITGEASGDKQFITVVTKSGNYFYIII
                     DRAEDGENTVHFLNQVDEADLTALMEDGQTEAPVCSCTDKCVAGSVNTACPVCSVNMS
                     ECAGVEAEPEPEETEQPPEEEKGGGMGILLVVLLVAAAGGGAFYYFKILKPKKDAAKG
                     SSSLDDLDFDEDDEETEVVETEQTEQEDDNL"
     gene            20733..22808
                     /locus_tag="PC592_000151"
     CDS             20733..22808
                     /locus_tag="PC592_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF4054178.1"
                     /translation="MKLVIAEKPSVGAAIAAVMGANEKRSGYFEGGGYLVSWCIGHLI
                     SLADAATYNEQFRKWKYDDLPIVPQEWQFIVASGKEQQFSILKDLMHRSDVTEIINAC
                     DSGREGELIFRFVYEQANCKKPFSRLWISSMEASAIREGFSNLKDGRGYDNLYQSALC
                     RAKADWLIGINATRLFSILYHKTLNVGRVQTPTLAMLVNRDYAISSFKKEKYHVVRLD
                     VGGVAALSERQDDEAAARQMKAACEKSQAVCTSLKKEKKTAAPPKLFDLTALQREANR
                     LYGFTAKQTLDYAQALYEKRLLTYPRTDSKYITSDMEGSTKELITGLCAALPFMQGVK
                     LQADLARICDNSKVTDHHAILPTAEFVKTGFSSLAESEKKLMTLVCAKLLCAVAAPYE
                     YEAVTAVFTCGGYTFTAKGRTTLCEGWREIERLSRAASGEQDEDAEPEAVLPPLAEGQ
                     TFDNPAAEISERYTQPPKAFTEDTLLSAMESAGKEDTPEDAERKGLGTTATRAGIIEK
                     LISAGFAERKGKKLIPTKDGYNLVAILPDSLTSPQLTAEWETRLTGIAKGSDSPADFM
                     RGIEEMTAGLVKTYSAISEDKAKLFTPQREAIGTCPRCGAAVYEGKKNFYCSDRACSF
                     VMWKNDRFFEQRKKAFTKAIAAALLKDGKVKIKGMYSTKTGKTFDGVVLLADTGGKYV
                     NFRVEQNRK"
     gene            22805..23173
                     /locus_tag="PC592_000152"
     CDS             22805..23173
                     /locus_tag="PC592_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDF4054179.1"
                     /translation="MIRLDEKQYRAVKKMTRAACANNDCGNCLLLDDGETCVCVQSIS
                     YSLLCRYFREAVLPADRQLCEQITRSGETDLKRCAVCGSTFAAGSNRAKYCPDCAAKI
                     RRRQKAQSERNRRLRIKTTT"
     gene            23299..26646
                     /locus_tag="PC592_000153"
     CDS             23299..26646
                     /locus_tag="PC592_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF4054180.1"
                     /translation="MPYSSYDHDKLEAAETMRIERRIYFEAKDREIAPYASLPIAQLL
                     SMRSESAAAEQAIFDDLKERAAAWEEQAGRTLLLDKTLEYVRTPHVQHTANEWQTTEH
                     NRHIRSNRVYQMNYYIYENTRYDKEAQKSIPYSWTLTWSVRTNSPSRTQAKIAGQDRK
                     VFTDKAAMEKYLNGRIKAYDRLFTEISPPIPQEYADYFKVNGMLMPDYTIEGEEPPQQ
                     QQAAAIPENTGQEKEREHMSEQFSIMIGNRSRFDAGDPGGYWLDMPATKEQLHEAMRN
                     VGITADNPQDFSIRGYSDDPEKHIALPYEMVCAADVDELNFLAARLEQLDPAEVGKLN
                     AALQQKNGLANIGQVIDFTYNVDFYVHIPEVHNYHDLGDYYLNQSGMVQMPEEWKGGI
                     DLSTFGRNAAAQEKGAFTEYGYIVESGDEWERQFEGREVPEEYRIMSYPQPERGEQDK
                     AYMDAAETQQADAQAAEPQQPRPVVPIILTSEKPAEKVKEITARLEQGVQAIFDSDRY
                     KEFLTAMSKFHDYSLNNTILIAMQGGNLVMGFRQWEKEFDRHVKKGEKGIKIFAPAPY
                     KVKKLVDKIDPETRKPMLDREGKVVKEEKEITVPAFKVITVFDISQTEGKEFPDLSVK
                     PLLADVEQYEDFFAALEKASPVPIAFEQITNGANGYFSLTDKRIAIKEGVSELQAVKT
                     AIHEIAHAKLHDVDLNAPPEQQNRVDRHTCEVEAESVAYTVCQHFGLDTSDYSFGYVA
                     GWSSGKEMTELKASLETIQTTAKELITEIEGHFTELQQQRQAEQEQGDTFSIYQLKRG
                     DETRDLRFEPYDRLQAAGLTIDRVNYELVYTAPLTKDMTLGDIWERFNIDHPADFKGH
                     SLSVSDIVVLHQNDEDTAHYVDSIGFQQVPEFLQEQQTPVFDKLPPEQQQALSDTVQD
                     TLQMLVDADKRIYGDVTGKTLEAIAAQGYSYKDGQLEKQQPEATPDSLLTGETVRTPR
                     GNFHITDMSREQIEAAGFGFHHASEDGKYLIMGNGTQAYAIAAEQPQRDNPLKHVEDT
                     IEQNDNNFDGLINNTPQTPTVADFEQRAKAGEAISVTDLAKAVKAEKREQPQKKPSIL
                     KKLDEYKKQAAQQPKDKQKEHKKDLEV"
     gene            26651..26860
                     /locus_tag="PC592_000154"
     CDS             26651..26860
                     /locus_tag="PC592_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HDF4054181.1"
                     /translation="MNTRFTIEEENIVAIYAEDSRETTLENILAAMPYMDEDMRQLAA
                     AAVNKLQAMTDSEFSEREFILTDEE"
     gene            complement(27062..28396)
                     /locus_tag="PC592_000155"
     CDS             complement(27062..28396)
                     /locus_tag="PC592_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF4054182.1"
                     /translation="MAVTKTHPIKSTLKAAIDYILNPEKTDGKLLASSFGCGLETADI
                     EFAWTREAAGDRGTHLGRHLIQSFAVGETTPEEAHKIGMELAGAVLGGKYEFVLTTHV
                     DKDHLHNHLIFNAVSFVDYKKYHSNKQSYHFIRRTSDRICKEHGLSVVVPGQDKGKSY
                     AEYTAEKQGTSYKAKLKTAIDTLIPQVKDFDELLRRLQEMGYEIKQGKYISFRAAGQE
                     RFTRTKTLGAAYTEEAIKERIKGVYVAKTKTLREDKKIRLVVDLENSIKAQQSAGYER
                     WAKIHNLKQAAKSMNFLTENKIEYYSELESKIADIMTAHDAAAKAVKEVEQRMSDLSL
                     LIKHTTTYRQLKPIYDEYRKSPDKEKYLRGHESEIILFEAAARALKEMQIKKLPDLAA
                     LRKEYRSLNDRKTKLYEDYRQAKKQMQEYGVVKKNVDSILYPSQSRAREQER"
     gene            complement(28357..28686)
                     /gene="mobC"
                     /locus_tag="PC592_000156"
     CDS             complement(28357..28686)
                     /gene="mobC"
                     /locus_tag="PC592_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF4054183.1"
                     /translation="MENRKRNIQMKFYVTEEEKRLIDEKMKQLPIKQYGAYFRKMAID
                     GYILVVDRSDTKAYIRELQAVSRNINQIAKRANATGTVYRQDIEDIKKAVDEIWRLQR
                     RTLLNQP"
     gene            complement(28888..29244)
                     /locus_tag="PC592_000157"
     CDS             complement(28888..29244)
                     /locus_tag="PC592_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054184.1"
                     /translation="MAKRPVPLYDFKAFGAAIKAARNEYGESRKKVSDELYISPRYLA
                     NIENKGQQPSLQVFYDLVTRYHISVDQFFFPNSNAEKSTGRRQLDALLDGMSDKGIRI
                     VTATAREITEVEKAED"
     gene            29601..29786
                     /locus_tag="PC592_000158"
     CDS             29601..29786
                     /locus_tag="PC592_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4054185.1"
                     /translation="MLKKYWIKCPICNGKTRVQVFHNTVLKDFPLFCPKCKLTHIIDV
                     EKLEIVIKNTEKQTFII"
     gene            29803..30786
                     /locus_tag="PC592_000159"
     CDS             29803..30786
                     /locus_tag="PC592_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF4054186.1"
                     /translation="MKRLPKYTPAEVRNDPYGFTYKEMSEVIGENEAKALYEELYKQL
                     PRKKNLSMLVKNICKSSDTEKYVYELKDNKYIETVFIKRRDGGTVCVSTQVGCPVGCI
                     FCESGRNGFVRNLTSSEIVQQIILLRRKVNRIVFMGMGEPLFNYDNLIKAIHILRDRY
                     GLNFPTDGITISTVGPVDQLKKLREEHLKIQLTISLHAATQSARNRIIPHMRIYAIED
                     VVKQALSYSERHNRKIVFAYLLLPGINDRPSDVRQLAKWFRGKKVMINVLQYNPTSNS
                     RIKAPQKREIVAFKHQLEQAGLEVTMRVSHGREINAACGQLANTYNKFKKK"
     gene            31262..32020
                     /locus_tag="PC592_000160"
                     /pseudo
     CDS             31262..32020
                     /locus_tag="PC592_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005921270.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(32075..33442)
                     /locus_tag="PC592_000161"
     CDS             complement(32075..33442)
                     /locus_tag="PC592_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF4054187.1"
                     /translation="MAYIKIFPIKVTDKKALDYIMNPGKTEEKLLISSFACSPESADL
                     EFAFTREEGKKNVMDKGNNLAFHLIQSFKPGEVDAETAHKLGKEFADEVLKGKYEYVI
                     STHVDQNHIHNHIIFNATSFVDHHKYVSNKRSYHKICRISNRICQENGLVTSMPTGEK
                     GKSYKENMEYHRGNSWKAKLKVAVDKAIWSSINYDEFLQKMKLAGYEIRQGKNLAFRA
                     PEQKNFTNMKSLGSYYTEENVLLRLEKNRHKTKSPRNVSREVRLFVNISAYVSTGNRA
                     GFERWAQLNNLKEAARTFNYLSENNLLNYEDFRQHIADIDNSIIATEQRISELISEIS
                     HQELIQKHCSSYRTCRKIIEDAKTAPDPQKYKATHQSEYKLHDSLKQQLQELGITKLP
                     SPERLQKKIDNLRNERSSAVKEKQDLEKRHSTLNTITANFNTLLSNDAHFKDITERRQ
                     KEHDL"
     gene            complement(33409..33732)
                     /locus_tag="PC592_000162"
     CDS             complement(33409..33732)
                     /locus_tag="PC592_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDF4054188.1"
                     /translation="MSNRKRNIQILFCVTPEEKKLIRQKMILSKTRNMGAYLRKMAID
                     GYIINTDTTPIKQVYEEMHKIGVNINQIAKKVNTTGELYPEEMEELKRMVNEIWHILK
                     SSPLK"
     gene            33990..34349
                     /locus_tag="PC592_000163"
     CDS             33990..34349
                     /locus_tag="PC592_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDF4054189.1"
                     /translation="MDREEIFEYVKKQYGTIPEYLWSSSPDSAVLRHQNGKWYAVIMN
                     AEKSKLGLNGDGTVEIIDVKCDPEMTGMIIQTYGFLPGYHMNKQHWITILLDGTVGES
                     KILDFLDMSYDLIDGKK"
     gene            34395..34865
                     /locus_tag="PC592_000164"
     CDS             34395..34865
                     /locus_tag="PC592_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054190.1"
                     /translation="MTKVNTMNTKLTRGDKAHKKFIEKLDVFKDGLKHGMDSLEMIHK
                     QTLDSSVEFTKVVSKSQEVERTALYDIIKKCEDETRRKEAFERLAELDRIKEKEVDTH
                     NDFLKNEREKANRNITGGILCLAVAGGLISSKQVRQMSGKALTTISKNLLRTKE"
     gene            34957..35766
                     /locus_tag="PC592_000165"
     CDS             34957..35766
                     /locus_tag="PC592_000165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054191.1"
                     /translation="MDSNTILSNILQEEVQYFYNCIRDYDEKRIIDIAMVDDVYAKVL
                     EYDMCDVQKEAVMKAGAALNDSNGTVIFAPSRDKTTLVVLSKKVLPQKDLDEVHGTVL
                     HELTHAHDYYDYADYLQISDYNTLFNSQYYNAFFLWTEFHARRIGYKRFIEYKFRKGW
                     KQFKKHRYEFLEGINANFSIYSSKGRLYDLMQAAGRYYTFIELCSSHTENFKGDILDG
                     NVEPDLLNILNEVYCFLAENREFKQFVNNIVIFDELLHKIDSMVSEQIEQV"
     gene            complement(35893..36123)
                     /locus_tag="PC592_000166"
     CDS             complement(35893..36123)
                     /locus_tag="PC592_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054192.1"
                     /translation="MAISNILKDIRIERNLIQEDLAEATGSCSRTIGRIERGERNPSL
                     EMAIRLAHYLNMSVEEIFKLDDGTSSQKKTEE"
     gene            complement(36191..36931)
                     /locus_tag="PC592_000167"
     CDS             complement(36191..36931)
                     /locus_tag="PC592_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDF4054193.1"
                     /translation="MRSIGRIIAENRKKKGLSQPELAELLSQQGIDVTAKAISKWETD
                     AREPGLHVFLTLCKLLDIEDIYDAYFGKNPYSVMDGLNQEGKDKIKDYAKILKASGLF
                     EPVIANIIPFRKKEIFMDIFGDAVSAGTGNFLTDSPKESYEVGDLAPDNADFGVRISG
                     DSMEPEYHNGEIAWIQQKDSICNGEVGIFYLNGDAYIKKLHDEPDGLFLISLNKKYKP
                     IAIQESDSFKIFGKVVGKCDASDILGFQ"
     gene            37124..38371
                     /gene="dinB"
                     /locus_tag="PC592_000168"
     CDS             37124..38371
                     /gene="dinB"
                     /locus_tag="PC592_000168"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF4054194.1"
                     /translation="MGDRTILHSDMNCFYASVEMLHHPELEGKPLAVGGDPEARHGIV
                     LTANYIAKKCGVKTGMALWQAKQVCPDIIFVPPRMDLYIRFSGMAKEIYAEYTDKIEP
                     YGIDEAWLDVTDSSSIKGDGMKIAQEISDRIKYELGITVSIGISWNKIFAKLGSDYKK
                     PDAITQFHRGNYKEIVWGLPVSDLLYVGRQTNKKLQKLGIHTIGQLAQTDEKLLDSHF
                     GKIGLVLWAFANGYDSDPVCTEGYEAPVKSIGNSTTTPRDLETDLDVWIILMALSESV
                     SARLRKHGFKCKVVEISIRDNGLNSITRQKRISQPTNITDEIVKAAFELFKKHYRWEH
                     PIRSLGVRGSDLVMEDIPVQLDLFDNQEKREKLERLDRAVDEIRRRFGYFSIQRAAMY
                     QDKVLSHLDAGTHTVHPHSYFHG"
     gene            38371..38598
                     /locus_tag="PC592_000169"
     CDS             38371..38598
                     /locus_tag="PC592_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDF4054195.1"
                     /translation="MGGIDLKQTLTRKQEESYQCIVRFTEEHGFPPTVRELGELLGVA
                     STSTVFSRIKQLEKSGYIRRLPASPRAIEIL"
     gene            38611..38850
                     /locus_tag="PC592_000170"
     CDS             38611..38850
                     /locus_tag="PC592_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005344271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054196.1"
                     /translation="MNKVYVDVVAEFSKEGCLIPILFVWEDGRKYKIDKILKIERCAS
                     RKAGGVGTMYTCMVQGKESHLFFEVDKWFMERKIS"
     gene            39081..39653
                     /locus_tag="PC592_000171"
     CDS             39081..39653
                     /locus_tag="PC592_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054197.1"
                     /translation="MTDRDYAIKSMKEITFQMATHAQNYLEVTMDRHYEDIKALMVNY
                     QKLILENKMVLEELEMECQEKINEDMAYALSYLDVYGKQLNVTKLRHEMNNLMVIYGL
                     SDMVYRGITLVKYYAPDGVMLSEIIHSCFCSHYNKTDVEVQQELGIGRTSFYKMKKQA
                     LRYLGFYFYEIVVPQAKNKRFKPSLGVEEE"
     gene            39663..40028
                     /locus_tag="PC592_000172"
     CDS             39663..40028
                     /locus_tag="PC592_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054198.1"
                     /translation="MKYENSMVKIADDIIRDQIADRNVQNKKQKWHDEYATLKFFRYI
                     CRNVGNLQEGEIQRLVWKLKQSDKKAVEKHLKGYAWEFDYEKMFSILTQNPVCQKVCQ
                     KNKYTSWMHLISRYCTEDC"
     gene            40190..40504
                     /locus_tag="PC592_000173"
     CDS             40190..40504
                     /locus_tag="PC592_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054199.1"
                     /translation="MDLKAVGQRIKMAREAKGLTQEDLAAMVELSPTHVSVIERGLKA
                     AKLDTFVAIANALEVSADSLLIDVVAHSVTGVTNELSEMIGKLPKEEQKKIIKAVRAL
                     TE"
     gene            40646..40864
                     /locus_tag="PC592_000174"
     CDS             40646..40864
                     /locus_tag="PC592_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation initiation factor Spo0A"
                     /protein_id="HDF4054200.1"
                     /translation="MHRKTIFEKVAEKFHTTPEEVYAEIQRAIDAGYDNPDPEVRAEW
                     RKVKIKGNRPTPEEVINYAVSTLTAEQR"
     gene            40984..41292
                     /locus_tag="PC592_000175"
     CDS             40984..41292
                     /locus_tag="PC592_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054201.1"
                     /translation="MNQDEILTVVANRNQIEDKEDFAKFLVKKCKDNSFQSVKFSTDY
                     GYATSLNLRVYLWEDEIEGQEPVMMVEYKPVEWGMDYDIVHDPEKFQMYVDGELMENP
                     "
     gene            41656..42129
                     /locus_tag="PC592_000176"
     CDS             41656..42129
                     /locus_tag="PC592_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4054202.1"
                     /translation="MYIEHPYKYDGKYYANVDGKMIEITKEVAYAMNNFYRSSQPRKI
                     EIKNEKGEVVERKLREIPYSETNGQDYEFSIEDFPDYSCDVEDSVISSAERRDIHKVI
                     NQLDAEERMIIYGIYFENKTQVQLARIMGVSRQVLAYKLNTILNKMRRMYQENIF"
     gene            42678..43061
                     /locus_tag="PC592_000177"
     CDS             42678..43061
                     /locus_tag="PC592_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF4054203.1"
                     /translation="MKIERGDILMVNLGQVPGTSLQSGIRPVVVVSNNKANTYSPVVT
                     VVPFTSRVYKKRYLPTHVFINRYEMVGLKRHGLVLAEQITSIDIQSIIQKCGHVSSDA
                     MRRITRAVEIQTGVYEEGDYDSRRI"
     gene            43042..43290
                     /locus_tag="PC592_000178"
     CDS             43042..43290
                     /locus_tag="PC592_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054204.1"
                     /translation="MTAEEYRKYLEQDFCDVNIDEMTDLLTIKADRNKSLKERRESYL
                     NKVGNPYLVRIGNMKVKVRFANNGISLEQAFENMLLSV"
     gene            43399..45090
                     /locus_tag="PC592_000179"
     CDS             43399..45090
                     /locus_tag="PC592_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054205.1"
                     /translation="MYQNFNKIYRAAIYVRLSKEDGDLSGSAKMESNSISNQKALILD
                     FLKDKKDIEVVSVRVDDGYSGSNFERPAFQAMLEDIRRGIVDCVVVKDLSRFGREYID
                     SGKYIERLFPALGVRFIAINDNYDSLQGKNQADEIIIPFKNLINDAYCRDISIKIRSN
                     LEIKRKKGECVTPFVAFGYQKVKADKHKLEIDPVAGSVVQDIFKMKLQGMSQDAIANR
                     LNELGVLSPFEYKISSGSHYETGFRQKEQALWSSVAVRRILENEVYIGNLVQGKRTTP
                     NHKVKQSYVKPEDDWIRIEKNHEPLVSERDFEIVQRLLGMDTRTSPDQKQVYLLSGIA
                     VCADCGAPMTRKVSTVGGKKYAYYLCSTNKETKRCSSHRIPEKDLENVVLVMLKQHIH
                     NILHLKRVLEFIGTVPFQEINVKKLQDRLEKKKMETERCKELRMMLYSDMKEGIVSKE
                     DYVELHAAYGKRLRNAEESIRAIQKEMDNMLEKADASNTWLDYFVKYQDIEVLTRTVI
                     VELIREIRVHDKKNIEIVFDFDDCYQALLTQLPAMGVEVATDPDNNLQVKIKEVV"
     gene            45092..46783
                     /locus_tag="PC592_000180"
     CDS             45092..46783
                     /locus_tag="PC592_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054206.1"
                     /translation="MARKSRKSIPETVSSAAVQEEIKRPFRAGLYARISMETEETIER
                     GTIETQVELMKNYVADTEDISVAEVYKDSDYSGTNFDRPGFTQMMEDIKHGKINCVIV
                     KDLSRLGRNYVETSNYIERVFPFFHVRFLAVTDDFDSFREGVDLTVPLKNIINEFYSK
                     DLAKKSSSAKKALWREGKFTGAWEPYGYRKSEQDRHQLVVDEEAAGHLRAIFSMYMDG
                     CSYSDIAKKLNADGVLSPTLQREYYRSGEKPSPESKPWNNYEVKRVLQDVHCTGDSVY
                     GKYQQSVFQGNKQRNRPESEWIYAENTHEGIIDKELFRQVQDKIREFTEEYKKRHQLN
                     NGAIRSQNFYTGKIRCGGCGNRMILSREKSGTFYYLCGANANHKSGGNQCKGHRVKKE
                     YVDEDVLRLIQSHMKTVLDTEKMIREMNSASRNQTQYLLLDKEVGKLRRELSRISKRK
                     SDLYEDYSERLITEEEYMQFSRIYSNEIENIKSRLDAVLTAQVRYSKDYHIEEGWGKV
                     IHTYMSKRKLTKEMVEAFVDSIIIHGKYDYEIKLVYDDQFAELQKIMKEKEVQSR"
     gene            46780..48357
                     /locus_tag="PC592_000181"
     CDS             46780..48357
                     /locus_tag="PC592_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015568863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054207.1"
                     /translation="MTENRKTAVYIRLSMEDENVDGRTKLESDSVTSQRILLKSFVID
                     QLGVDESDILEYVDDGVSGTHFKRNGFQQLQEDMKSGQIGCVVVKDFSRFGRDYLEVG
                     FYIEYIFPLLQIRFISINDSYDSAASSGMTGGMNVALKNLVYNMYSLDLSKKISSAMQ
                     TRMKNGTRLPVNARYGYRKGKDGRLEIDPDSAKVVKMIFQMAAEGMSFAEITRELNKQ
                     EIATCDEQKMSRGEQVQFRRFDTIMKKRWNPTTVSAIIRDEIYIGTRIWGKTRCSMHT
                     GHKAVINDESDWIRLENHHDPIVDRELFEKANRLHPKKSRGVAETRTNYTLARRKKQP
                     ALMLCAHCGHCLVRETEHLLKCSDGRTSGDHVCKSLVVRREPLEKNIMELVHQFAFSM
                     LENRKIVESRNQSKGMETNVAELLKQSRQLSSEKMKLYDEYKDDRIDRELYKQKAGQI
                     GRQLEEIRRKIAESERDAKILEQNNTAKEMKLEEFLSMEKFDTEKLREIIKVIRVHSQ
                     EEIEIEWNFDDVFLGQR"
     gene            48414..48647
                     /locus_tag="PC592_000182"
     CDS             48414..48647
                     /locus_tag="PC592_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4054208.1"
                     /translation="MEWSGTFRQEKRIIFFVPYLTRPHTFRHTFCTNMANKGMSPNIL
                     QYIMGHKNITMTLGYYAHGSFSSARAEMERLSA"
     gene            complement(48905..49705)
                     /locus_tag="PC592_000183"
     CDS             complement(48905..49705)
                     /locus_tag="PC592_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4054209.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYASSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGASKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(49900..51498)
                     /locus_tag="PC592_000184"
     CDS             complement(49900..51498)
                     /locus_tag="PC592_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054210.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGIKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFNYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEVVKLIYNKYLELRSLSKLYKYIYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILEYLKNNGMDIVGTPDKKCGVLTYAKNTTNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRIATGKTALLSGFIKCGKCGSNMRITYKGR
                     KTDKDLKYYYICGTKKTLGADNCNCKNLNGPLVESLIIDKIKNCKEESIISTFNNNNI
                     KTGNIFNVLKSETNLLKNQILDKEKLIKNLVIELAKNTDSIASDYIVSQIENLNSEIN
                     ILKDKLNTLESSNANISSDSINLDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSNLGNLNIIYMGAEMDNSVSLSN"
     gene            51826..52002
                     /locus_tag="PC592_000185"
     CDS             51826..52002
                     /locus_tag="PC592_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054211.1"
                     /translation="MEINVIEIFPKDKAKLNEIEMNKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            52176..53306
                     /locus_tag="PC592_000186"
     CDS             52176..53306
                     /locus_tag="PC592_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF4054212.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLVNSTYQVFEEIVPDPPIEVVVSGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSDTAKKYAQIAKLVGLGNANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILNNIK"
     gene            53547..53897
                     /locus_tag="PC592_000187"
     CDS             53547..53897
                     /locus_tag="PC592_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF4054213.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            53905..54354
                     /locus_tag="PC592_000188"
     CDS             53905..54354
                     /locus_tag="PC592_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HDF4054214.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELNYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKSKNIDEV"
     gene            54457..55032
                     /locus_tag="PC592_000189"
     CDS             54457..55032
                     /locus_tag="PC592_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF4054215.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            55025..56434
                     /locus_tag="PC592_000190"
     CDS             55025..56434
                     /locus_tag="PC592_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HDF4054216.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     ILSKIDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGNLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFEDIL
                     MDENYDETNEVSIDNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGSYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFL
                     DREHGTIQILINKDNNYRNIAIIDDGVGFDSDNINKNSLGTYIIDSYITQMLKGNIER
                     KSNKNGTEILITIPTQINI"
     gene            56618..58051
                     /gene="eutA"
                     /locus_tag="PC592_000191"
     CDS             56618..58051
                     /gene="eutA"
                     /locus_tag="PC592_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDF4054217.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKVDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVIDTGCLDIGGRLIKIDKISKKITYISPKIDKIIKDNNLNLQVGTIATIENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISVDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCKYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYKKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            58069..59433
                     /locus_tag="PC592_000192"
     CDS             58069..59433
                     /locus_tag="PC592_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HDF4054218.1"
                     /translation="MILKTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWILD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIRVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKYG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            59446..60327
                     /gene="eutC"
                     /locus_tag="PC592_000193"
     CDS             59446..60327
                     /gene="eutC"
                     /locus_tag="PC592_000193"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HDF4054219.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRTGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            60347..61000
                     /gene="eutL"
                     /locus_tag="PC592_000194"
     CDS             60347..61000
                     /gene="eutL"
                     /locus_tag="PC592_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDF4054220.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            61011..61715
                     /locus_tag="PC592_000195"
     CDS             61011..61715
                     /locus_tag="PC592_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF4054221.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRIDKVGAGIVTLT
                     ICGDVGAVKSALEAGEIAASRVGTLRTSHIIPRIHDEVTDALFKTKEPKVCEVSEDKE
                     KNFEVTLETTDNVSKNLSEKEDVILDVTENSGNIEKLYSDIDKINKEIETVDDILTEA
                     NKGKIENTNIDKKVLEQVKIENFDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLK
                     KEELINLVKKLSRRDR"
     gene            61718..63187
                     /locus_tag="PC592_000196"
     CDS             61718..63187
                     /locus_tag="PC592_000196"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HDF4054222.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQDKLSKMSQEQIDKIVKAIA
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIISEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISD
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESKKLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHANDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSIDKEELINLLVQKLVKELG"
     gene            63273..63560
                     /gene="eutM"
                     /locus_tag="PC592_000197"
     CDS             63273..63560
                     /gene="eutM"
                     /locus_tag="PC592_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDF4054223.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            63687..64448
                     /locus_tag="PC592_000198"
     CDS             63687..64448
                     /locus_tag="PC592_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HDF4054224.1"
                     /translation="MGVLTENEIKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKTYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKAQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLEEKLEDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            64461..65090
                     /locus_tag="PC592_000199"
     CDS             64461..65090
                     /locus_tag="PC592_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF4054225.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGK
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGLTLGL
                     KAPIKQSGDLEGTLSIKISTQHGEVELDKGLMVAKRHIHMTPKDAENFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKV"
     gene            65132..65857
                     /locus_tag="PC592_000200"
     CDS             65132..65857
                     /locus_tag="PC592_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HDF4054226.1"
                     /translation="MNYDNLVDLIMEEIYKKVNSNEIKISNKPKAVIVFEQDTNKFNL
                     LKDEFEIVEFDKSIKECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMSGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFISFEDEICKFGVEIIKDLNAITKNKLNIKRELESTI
                     GSKKEDTKALDKDVLNLTSVESVKIDNEFSLDLRNRKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            65870..66142
                     /locus_tag="PC592_000201"
     CDS             65870..66142
                     /locus_tag="PC592_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HDF4054227.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKGTYKEGFMVAA
                     DNAGAGNGDLVLISRGSSARESIEKAHVPVDATIVGVVDSFEVFDE"
     gene            66135..66686
                     /locus_tag="PC592_000202"
     CDS             66135..66686
                     /locus_tag="PC592_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF4054228.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     VVGGETSYVNECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDNIVSIGVVE
                     SGKVCAGIKMLDRTLKSGELVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESEDVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            66698..67789
                     /gene="eutH"
                     /locus_tag="PC592_000203"
     CDS             66698..67789
                     /gene="eutH"
                     /locus_tag="PC592_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF4054229.1"
                     /translation="MSINEIIIYVMVIFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEIMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGFAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            67791..68264
                     /locus_tag="PC592_000204"
     CDS             67791..68264
                     /locus_tag="PC592_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HDF4054230.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(68384..69433)
                     /locus_tag="PC592_000205"
     CDS             complement(68384..69433)
                     /locus_tag="PC592_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4054231.1"
                     /translation="MSLNKLFQNLYIYNESELFYKNYYFAKQNPESLKLFIDNLDEDY
                     IVNNNLIIPYIYNEKIPQLMKDETYFECNSKDNVILIKHNRYTPQFVHEHIFFEMIYV
                     LSGKCYQVINHHNVHMKEGDICIVSPGVKHSIGVFDDSIIINVLIRRSTFEDAFFDFL
                     RNNNLLSSFFLNSIYKDKQNDYILFHTNNDKSIEISILEMLSEYNEQDRYYNNILNHL
                     IMVFFAKLLRDYEDSIEVPNVTKKGTLNHTNILTYIQDNYVDITLEELANKFHFSIPY
                     CSKIIKEIAGCNFTQLLQRIRLERAESLLMNTNIPIADISNNVGYPNVEHFIRLFNKK
                     YNMSPSKYRKNTTKV"
     gene            69606..70973
                     /locus_tag="PC592_000206"
     CDS             69606..70973
                     /locus_tag="PC592_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4054232.1"
                     /translation="MTTLKVVDEKNVPGIWRQRIGYGSSDLACNLIWQMISLYLLYFY
                     TDIMGLSAVAISFMFVVTRVIDGITDLLVGYCIDKTNTRWGKSRPYFLFGAVPFALFA
                     VLAFSVPDISLSGKLIYAYVTYIGLSLTYTIVNIPMASILPSLTDDTNERTALSTSRK
                     FFGFLGSTIVSYSALTLVGKFGGTDEALGFKVVMMLFAFIGCAIFLFTFSNVRERVEI
                     KSENVTLFQTIKSLKENKPWKLFALNILFMWTGFFIQSSALIYYFSYNVGSKSLATTV
                     ATIMSIIPILANFLVPILAKRLGKRNLYITSAAVQFIGLGIILIANLNISLIIAGSIV
                     SAFGYGIKESIYFSMQADPVDYGIWKTGINTTGTLNSVNGFLGKCAQAISGGLGGALL
                     AWGGYIAKAEVQPASALVAIKIMYVYIPMALLICSMITMKFYDLDKQYPKIKADLDAR
                     KISEE"
     gene            71004..72605
                     /locus_tag="PC592_000207"
     CDS             71004..72605
                     /locus_tag="PC592_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HDF4054233.1"
                     /translation="MSNITNSIKDFRMEINQDFIDKAEKLKPILIEKLIKPKQIVNIK
                     MGKNDWEVIDTKSIDEISNISLGKGESICIDFGNHQVGYVNFKIKPIGSPPDAPTHLR
                     IKLGETLCEIGEDSSTYKGSISSSWIQEETMHIDILPDKINMKRRYAFRYLEIKVLDT
                     SPKYKVIVEDVSCNFVSSVDMSEINYLSNIDDDLIKIDKIALKTMQDCMQTVFEDGPK
                     RDRRLWIGDLRLQAITNYETFKNNDLVKRCLYLFAGLTQNRGQVGACLFIEPKLLVDD
                     TALFDYSLFFISCLHDYYEATKDMEILNELWKVAYIQAKLALERVGINGVVYDSDDWW
                     CFLDWKEGLNKQAGAQGVLIYALKQAHKLAIILGDNEKKEELEYEIDRVVQGAKNHLW
                     DEKQGFFVSGSEKQVSWISQIWCVLADVFDKETNTKILDNLLDNPPDMDIVTPYAYHH
                     LVECLILNNRKEKALECIRGYWGEMVKDGADCFWELYNPNDKYVSPYGSRIINSYCHA
                     WSCTPSYFIRKYFGRDSKEVTSKYK"
     gene            complement(72752..73351)
                     /locus_tag="PC592_000208"
     CDS             complement(72752..73351)
                     /locus_tag="PC592_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4054234.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGDAISIKVQL"
     gene            73521..74879
                     /locus_tag="PC592_000209"
     CDS             73521..74879
                     /locus_tag="PC592_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054235.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKIRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERIDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHESKISQNQKILLDEKFTLDDSIKNLSNIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFNDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            74872..75504
                     /locus_tag="PC592_000210"
     CDS             74872..75504
                     /locus_tag="PC592_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF4054236.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNTSVEETFKKSGIPVKVDKSNGQVTFGERTMFDIDSDVLKPEAKEML
                     KMFVPKYMETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            75833..76990
                     /locus_tag="PC592_000211"
     CDS             75833..76990
                     /locus_tag="PC592_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4054237.1"
                     /translation="MIERNIKNKKNSKIKALILLFIVSISIYLTGCATSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFINTGNSDAILIQDGKTFTLIDGGDNDDEKLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALASKDLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILS
                     KLDKVDLLKVAHHGSRSSSSQEFLDKVSPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNNNTSKNDSFKNKQNT
                     SNSAEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYVK"
     gene            complement(77109..77744)
                     /gene="lexA"
                     /locus_tag="PC592_000212"
     CDS             complement(77109..77744)
                     /gene="lexA"
                     /locus_tag="PC592_000212"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDF4054238.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLKVKGESMINAGILDEDYVVVDKKNTAFNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(77848..78975)
                     /locus_tag="PC592_000213"
     CDS             complement(77848..78975)
                     /locus_tag="PC592_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4054239.1"
                     /translation="MNNDKKVIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNAECIKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRENGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(79298..80143)
                     /locus_tag="PC592_000214"
     CDS             complement(79298..80143)
                     /locus_tag="PC592_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054240.1"
                     /translation="MIYIIEILKISIINIFCFIGIFIVFGLIFSITESLNNKFIFSSF
                     GKIGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTVMIILIFKILLPDSYMKVTQNIDLNLYVSMINNLDISG
                     FIYIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFAISLITYLFGFDNLNISSLIVKYNIFVSLFMAIGLIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(80172..80543)
                     /locus_tag="PC592_000215"
     CDS             complement(80172..80543)
                     /locus_tag="PC592_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF4054241.1"
                     /translation="MKLKLLVEEYAVCRLNNDTKIPTWIDTERFYSITRTDDELSIVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILNCNGYEVE"
     gene            complement(80696..80956)
                     /locus_tag="PC592_000216"
     CDS             complement(80696..80956)
                     /locus_tag="PC592_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HDF4054242.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGIAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(81145..82089)
                     /locus_tag="PC592_000217"
     CDS             complement(81145..82089)
                     /locus_tag="PC592_000217"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDF4054243.1"
                     /translation="MIENNSEKIKVLENDIKQLIIISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSPYEKVMLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSIVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYTKFRNIGKCL"
     gene            complement(82110..82964)
                     /locus_tag="PC592_000218"
     CDS             complement(82110..82964)
                     /locus_tag="PC592_000218"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDF4054244.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(82979..84340)
                     /gene="accC"
                     /locus_tag="PC592_000219"
     CDS             complement(82979..84340)
                     /gene="accC"
                     /locus_tag="PC592_000219"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDF4054245.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEENNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(84356..84808)
                     /gene="accB"
                     /locus_tag="PC592_000220"
     CDS             complement(84356..84808)
                     /gene="accB"
                     /locus_tag="PC592_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDF4054246.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQATSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADNFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(85078..85524)
                     /locus_tag="PC592_000221"
     CDS             complement(85078..85524)
                     /locus_tag="PC592_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054247.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILTTVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKGNDTNLKESEV"
     gene            85799..86077
                     /locus_tag="PC592_000222"
     CDS             85799..86077
                     /locus_tag="PC592_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054248.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(86206..86952)
                     /locus_tag="PC592_000223"
     CDS             complement(86206..86952)
                     /locus_tag="PC592_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054249.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEI
                     PKEALSLKDMDSINLANNYLIDDSVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VNIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLDFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILNDKNDLNTSQEVLITVNVK"
     gene            complement(87081..87725)
                     /gene="trmB"
                     /locus_tag="PC592_000224"
     CDS             complement(87081..87725)
                     /gene="trmB"
                     /locus_tag="PC592_000224"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDF4054250.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(87863..88183)
                     /locus_tag="PC592_000225"
     CDS             complement(87863..88183)
                     /locus_tag="PC592_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HDF4054251.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(88502..89188)
                     /locus_tag="PC592_000226"
     CDS             complement(88502..89188)
                     /locus_tag="PC592_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054252.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILYIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLDKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(89203..91680)
                     /locus_tag="PC592_000227"
     CDS             complement(89203..91680)
                     /locus_tag="PC592_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF4054253.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMSGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLIAADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRHTRGVNALLPKETLSKIINKGSGYTRVLIESEEEMTENL
                     VNKLSEELSTEKYTVSNTINETKIISDARQKIMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTHILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPTVISPIGVIISVIVAIIVSLFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSVLLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKNILPLYVMNNEISGNGVTLSRLEGTDNIELYNSM
                     FAINYTNFEIKKQVTEAFKDKRSVILNEDTLKKVGLSIGDTITLSKDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRDLFGDTYNWSRTVE
                     EFYNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(91900..93297)
                     /locus_tag="PC592_000228"
     CDS             complement(91900..93297)
                     /locus_tag="PC592_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4054254.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLTLANQNNSSNGTVYFNAIKNNKNDYIYIIYFPLNISKVNMFFDGSK
                     FVGGKSIVFSIIGIIFLIILLSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     TDIYDSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSSI
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRLLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDYTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSKTKIEGTGLGLAITKQIIEVHGGNISVE
                     SILGLGSSFYIIFPI"
     gene            93796..94656
                     /locus_tag="PC592_000229"
     CDS             93796..94656
                     /locus_tag="PC592_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF4054255.1"
                     /translation="MKKQKSPILLEMLGLFLGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(94897..95454)
                     /locus_tag="PC592_000230"
     CDS             complement(94897..95454)
                     /locus_tag="PC592_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4054256.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKKDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(95644..96531)
                     /locus_tag="PC592_000231"
     CDS             complement(95644..96531)
                     /locus_tag="PC592_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4054257.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENGKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            96650..97849
                     /locus_tag="PC592_000232"
     CDS             96650..97849
                     /locus_tag="PC592_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HDF4054258.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(98054..100609)
                     /locus_tag="PC592_000233"
     CDS             complement(98054..100609)
                     /locus_tag="PC592_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF4054259.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKKYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETAMEGFVNDYLKPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     AYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILISVRVVHQLNKYSSIESMKNFKITNTKK
                     RILESVKHSNMTKVLSHKYMTQKKGLFVGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNIEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKIMKPTGEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFNIENYNSVSIKKTEDSNS
                     VELSEDIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFSLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINAPLYIGMIILNITISIVAVIIPVRQILKSDIISEINQK"
     gene            complement(100606..101292)
                     /locus_tag="PC592_000234"
     CDS             complement(100606..101292)
                     /locus_tag="PC592_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054260.1"
                     /translation="MSILVTNNLVKHYGKDETKVKALNGVSIEIERATFTAIVGTSGS
                     GKSTLLNIIGGLDSPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(101367..102275)
                     /locus_tag="PC592_000235"
     CDS             complement(101367..102275)
                     /locus_tag="PC592_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4054261.1"
                     /translation="MFILAFIICTVVIFIVSTKINQKRYDELSLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKLEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRVNLEPFSDIKLVHNKKWIIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVANQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(102277..102948)
                     /locus_tag="PC592_000236"
     CDS             complement(102277..102948)
                     /locus_tag="PC592_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4054262.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQLIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKVCLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDENIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            103210..104274
                     /locus_tag="PC592_000237"
     CDS             103210..104274
                     /locus_tag="PC592_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HDF4054263.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEVNLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            104432..105118
                     /locus_tag="PC592_000238"
     CDS             104432..105118
                     /locus_tag="PC592_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4054264.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSAMKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINVFKQKVKAFLNHFTTKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKNILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLQYIKTVYGMG
                     YMWLGERNEF"
     gene            105108..106139
                     /locus_tag="PC592_000239"
     CDS             105108..106139
                     /locus_tag="PC592_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4054265.1"
                     /translation="MNFKKFSCSSIYLIIAIGIIFTAILFNISIYIITDDLKLVTLLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQN
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVTTECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSEIGKGS
                     TFSIFLPNK"
     gene            106221..106886
                     /locus_tag="PC592_000240"
     CDS             106221..106886
                     /locus_tag="PC592_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054266.1"
                     /translation="MSILQVINLKKYYGQNSNITKALDSVTLYIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            106899..109316
                     /locus_tag="PC592_000241"
     CDS             106899..109316
                     /locus_tag="PC592_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4054267.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKTKNILYQDKNFSSVGAYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGNLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIIGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESIPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIALSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMRADLFIILILSLVMFLTVRISLFKPTRIISKISAIEAMQYTE
                     TKFRKKVKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYKHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPCVKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYRLNLKVGDTVTFNIFSGNDIIKKKMKIMGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEIEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLQNMLYREGLNISIKAICISSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(109497..110288)
                     /locus_tag="PC592_000242"
     CDS             complement(109497..110288)
                     /locus_tag="PC592_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF4054268.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYINKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFRKNTQSNENISIIQGNAMDLSI
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFVAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSVFNVTRLHYVASDGL
                     ALYMREAVDSMNDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(110321..110908)
                     /locus_tag="PC592_000243"
     CDS             complement(110321..110908)
                     /locus_tag="PC592_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4054269.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNKYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGMAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(111086..112477)
                     /locus_tag="PC592_000244"
     CDS             complement(111086..112477)
                     /locus_tag="PC592_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054270.1"
                     /translation="MEKLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFS
                     PKGRFDSYPISITVGILVACFVMFSERLDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSLILFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIISPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSIFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCDTGVEKGLIGLMGGVIAAKGGTWGLVVGFILYFVLIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(112644..112853)
                     /locus_tag="PC592_000245"
                     /pseudo
     CDS             complement(112644..112853)
                     /locus_tag="PC592_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
BASE COUNT        38082 a        19527 c        21230 g        34079 t
ORIGIN      
        1 actatggtga cagcgtaagc attgaaacac agcggacaat cctgcaacag tacgcaaagg
       61 aacaggggct tcatgtagtc ggtgagtatg tggacgatgg ctggtcgggg acgaactttg
      121 aacggccgga ttttcagcgc atgatggacg atatggaagc cggaaaagta aactgcattg
      181 tcacgaaaga cctgtcccgt ttcgggcggg aacatgtgat gatggactac tatctggaat
      241 ttctgttccc ggagaaacgg gttcgctaca tcgccgttgc ggagaatgag gacacagaga
      301 aagggctttc cgattttgtc ccgttcaaaa acctgttcaa tgaatggttt gcgaaagata
      361 caagccgcaa ggtaaaggcc gctttcaaag caaagtttgc cacaggacag cgtatcggcg
      421 cctatgctcc catcgggtac aggaaacacc cggaaatcaa aaacaagctg ataatcgacg
      481 aggaaacccg ctggatagtg gagaagattt ttgaccttgc tattcatggc agaggggcgg
      541 ccagtatcac aagaatactg attgcggaaa aggttcccac accgggattt atcaacttcc
      601 agcgtgacgg gacttttgca aacatctatg cgggtgcgcc ggaggaaaaa agctacgcat
      661 ggacgatagc ccaggtcaag agcattatga aagacgaaac ctatatcggc cataccattc
      721 attaccggga aacgaacatt tcctttaaga acaagcggag ggtacgcaag ccccaaagtg
      781 aatgggtgcg ggtggagaac acgcaggagc cgattatcag cgagcaggtt ttccggcagg
      841 tacaggagca gatagcaaac cgccgcagga agtgcaagga tggtacaacg cagatttttt
      901 ccggattggt aaaatgtgcg gattgcggct ggtcgctgtc ctatggggag aacaggcaga
      961 acagcaagcc ttacggccat tatcattgta gcaagtacgg gcagggcaca cgccaatgct
     1021 ccatgcacta tatccgttat gatgtgcttt atgcctatgt cctctcccgt ctgcaatact
     1081 ggtcggggct ggtacagcat gatgaagaac ggctcttgaa gcagctgtta aatgccactg
     1141 ataagggaca ggctgccgca agaaagaagc aggccgcaga actgaaaaag gcagagaagc
     1201 gaaaagccga agtcgatact ttgtttgccc ggacgtatga ggactgggcg gcggggcgta
     1261 tcacggaata caacttctct atgctgtccg ggaagtacca aagcgaacag gctgaactgg
     1321 acgaaaagat tgaacagctt caatccgcta tcgccactga aagccagaac gccgtagacg
     1381 cagaaaaatg gattgccttg atgaaagagt gcgtcaatcc aacagaactg accgccgaac
     1441 ttttgaatat gctgattgaa aaaatcgttg tccatgaagc ggtcaaaggt gaggacggaa
     1501 gccgggaaca ggaggtagaa atcttctacc gctttatcgg caaaattgat tgaatgatac
     1561 caatatcttt aactatgtga taccggcaga ggatatccga acattgactc actaaaggaa
     1621 atatctaagt tcttttcggt gactattgat gagttattgt ctggagaaaa gctgctttcc
     1681 attgcagaaa aagagaataa agcgaacctt caaagaatgt gcagtttgct ttttggaatt
     1741 gtggatttgt tttcttttat gctgattgta ttgcctcttt atccgaaccc aattaacgga
     1801 tatatttatt cggtgaacct attttcatat actgacacag cattctttaa tataatactg
     1861 tattgggtct cttaccttgc tctgattgtt atgggaatca caaaaattgc tttgacacag
     1921 ctcaaaacag aaaggggaca aagcattata acgagccttt cactgggatt gagtatttta
     1981 actgtattgt atttaggcat ggcaagagaa gcgtatgcaa ttacagtcgc atttatgttg
     2041 ttgctaataa aaggcatact gcttctaaaa tatacccaaa attcgtaaat ttccagttcc
     2101 acgcatcata atgacaattt aataatgact aagccaaagg cgatcaaccg taaaaagttg
     2161 gtcgctttta ttttatccat tatcgagaaa ggagttgatg aaaatgccca taccacatct
     2221 gaacatacga attgttcaga gaagcaaagg cagttctgct gttgccggag ctgcctatca
     2281 agccggagaa aaattgtttt ccgagtacga tcagaaaaac aaagaccacc gcagaaaaca
     2341 aaaggaagtt gtttacacgg aaatcatgct tccggcaaat gctccacccg aatatgccga
     2401 cagagaaacg ctctggaact cagccgagga ggtggagaag caatggaact cacagcttgc
     2461 aaggcgtttc gttgttgccc tgccgagaga agttcccctt gaaatgtgtc cgcagatgtt
     2521 acaggaatac tgcgaggagt actttgtctc caaaggaatg tgttgtgata ttgcaatcca
     2581 tgaccccgac ccaccgggac acaatcccca ttgtcacatc atgctgacta tgcgagccat
     2641 tgatgaaaat ggaaagtgga tgccaaagag ccgaaaggtt tatgaccttg acgagaacgg
     2701 cgagcgtatc aaacttccct ccggcagatg gaaaagccat aaggaagata ctgttgattg
     2761 gaacgaacag tatcacgccg aggaatggag acacggatgg gaagttatcc agaataaata
     2821 tctggagctt gccggaagtc ccgaacgagt ggatatgcgt tcttatgcca gacaagggat
     2881 tgatgttatc ccgacagtcc acatgggagc cgctgtctct gctatggaac gcaaaggcat
     2941 tgaaaccaat atcggtaatc tcaaccgtga catcaaatct gccaacagtc tgatggcagc
     3001 catccgcaaa accatcaagt ctctgcttga atggattgct gatgtaagcg aagccacgaa
     3061 agaagctctt gctgaaatga aagaacagaa cgcatccccg acacttgccg gattgctcaa
     3121 tgagtatctt aatgtcagaa aagaggaacg ccgggactgg tctcgctacg gacagaacaa
     3181 aggcagtctt gctgatgtgc aggcagtttc caaagctgtc gcatatttga gagaccacaa
     3241 tctctacacg ctgaaagatt tagatgaagc tctgcaagaa gtgaatggca gagccgcatc
     3301 aatccgaagt gcgattaaga cagccgagac ccgaatgaaa accatcacgc agattcagaa
     3361 agcggtctcc gtctgcaaag agcacaaagc agtcaaagac aagtatctga aaatcggatg
     3421 gaaagcggca caggcagttt acgctgagac tcacaaggac gctctttctg cttttgacaa
     3481 atcgttccgt tacctcaaaa agcaaggact tgaccttcgt gtagatctga ctgcgttgca
     3541 atcagaattt gacactctgg aaaagtccgt tgcagaaaac aatgcgaagc tgtccgaggt
     3601 caaagccgag cttcagccac tgaaagatgt ccgctactgg ataagcaaag tcatcgagcc
     3661 ggaacagggc gaggttgaaa agaagccgga gccgaagcac tccgtcacgg aaaagatgaa
     3721 gtatctgcaa gagcagaaaa aacagctgga gccgaaatct ccgcagcaca aacagaaaaa
     3781 acagaatatg gaactctaac acggcacttg cctttttcat tgtgaaaagt cgagtgcctt
     3841 ttttcgtttc agagaggaag tgatgatttg aatgtatttg aagcagtaaa acccaatata
     3901 agcacccgac aggcggctga gatgtacggc atcaaggtca accgcaacgg catggcagtc
     3961 tgcccatttc acaatgataa gaacccaagc atgaaagtcg ataagcgttt tcattgcttt
     4021 gcttgccaag ctgacggaga tgtaattgac ttcgtttccc gtctgtgcgg tctgccctgc
     4081 aaagaagcag ctatgaaact ggctgacgat tttggtatca gctatgacag cagacacaag
     4141 ccgacagtca gaccccatat ccgagaacct actgccgagc aactttatca aaaagaagaa
     4201 gcacgatgtt acagagtgct gacagattat tttcatcttc tgcgaagatg ggagacccaa
     4261 cacgcaccga aacagccgga tgatgtgtgg catccgctgt tcgtggaagc cctgcaaaga
     4321 aaaagccata tcgaatatct cattgatact ttgattgacg gcacgaaaga agaaaaacag
     4381 gctcttgtag cggagcaaag aaaagaggtg atgaaacttg aacaacgaat tgcagaatac
     4441 cgtggacgaa gtccgaaaca gtttggagca gagccagaaa ggtaaggtct ataacacagc
     4501 cgccaattac aagagggttc tgcaatgcga ccctctgcta aaaggtgcta tccgaaaaaa
     4561 tctgctgacg gagcgaattg atattgtaaa gcccctcggc tggtatcgtg acagtaccac
     4621 cctaaccgat gtggatataa agtatctggt tctgtatttt gaagaaaact acggactgac
     4681 tgttgaaaag aaaatcgtgg atgcgataac ggtgatcgcc aacgaaaacc gttatcatcc
     4741 agtctgcgat tttcttaatt ctctgaaatg ggacggacag gaacgcatcc gccattgtct
     4801 gcatcatttc ctcggttcag aagaaaacga gtacacttat gaagcattga agctgtttat
     4861 gctcggtgca atctcacgag tattcaagcc gggatgcaaa tttgaagtca tgctctgtct
     4921 ggtaggtggt caaggtgcag gaaagtccac attcttccgt ctgcttgccg tcaatgatga
     4981 ctggttctct gatgatttga agaaactgga cgatgataat gtctatcgca agatgcaagg
     5041 gcattggata atcgaaatgt ctgaaatgat tgccacagca aacgccaaga gcattgaaga
     5101 aatcaagtcc tttctgagcc gacaaaagga aacatacaag ataccgtatg agacccatcc
     5161 ggcagacaga aagagacaat gcgtgtttgg aggttcttcc aatacacttg attttcttcc
     5221 gcttgaccgt acaggcaacc gccgctttct tcctgtcatg gtctgcccgg aacaggcaga
     5281 ggttcacatt ctggaagatg aagctacatc cagagaatat atcattcaga tgtgggcaga
     5341 agcgatggag atttaccgaa gcggcaattt caagctgaaa ctcagccgtt caacagatga
     5401 atttctgaaa gcccatcaga aagagttcat gccggaggac accaaagccg gacagattat
     5461 tgattatctg gaacgctatt ccggcaatac agtctgctcc aagcagcttt atcgtgaagc
     5521 gttgggacac gactatgacg agccgaagca atgggaactg cgagaaatca acgatattat
     5581 gaataatgcc gtcacaggtt ggaaggcatt tgctaaccct cgctattttc cagagccata
     5641 ccgcagacag agaggttggg aacgcatccc catcgacaac gagcctgaca acaacacagg
     5701 aaaatttcac gaactgacgg aagcagaaat gcaacagctt gaacttccga aagaatggtt
     5761 ggaataaaaa ttgctgttcg ttgtcgggca gattgtcaag ccggttgtcg gtctggttgt
     5821 cgggcagaaa gcgaaaattc cttgattttg tggggctttt ctttctctga caacaatgac
     5881 aacagaaata taaaagaaaa agtaaatagt aaaaagatag ataagcccga ttaagaaaaa
     5941 aggttttcag aagtccgttg tcggtacttc gttgtcagac ctttccttgt cgggcttttc
     6001 tcatttcgag gaggtattca atgaacacaa acacaatcca gaccaccgca cagcacacac
     6061 agccttgcta ccgcaagacc atcgacaaga ccacctatgt ggttcgtgtc catttcagcg
     6121 aaaacgcaaa agagacgatg gaggacaaaa tcaagcgtct gcttcgtgag gaggtggcga
     6181 aaatgtgact tttttgtaaa catgattaaa aagtccttga caatttgcat caggcaaaac
     6241 ggcaaagtca atccttattt cctgcggcgc aaggttagcc ccctttgaca tacgggaact
     6301 gcgcgaactc atggaaaccg acgaaatgga gcttgacact ttgggagata gaaaaacggc
     6361 attgttcgtt atcatctccg acaccgacga cactttcaat tttgttgttt ccattctcta
     6421 cacgcagctt ttcaacttgt tatgcgacaa agccgacgat gtttacggcg ggcggctgcc
     6481 tgttcatgtg cgctgcctgt tagatgaatt tgcgaatatc ggtcaaatcc cgaagtttga
     6541 aaagctcata gcgaccatac gaagccgcga aatatcggct tctattattt tgcaatcaca
     6601 gtcgcagcta aaggcaatct acaaggacaa cgccgatacc atagtcggca actgcgacac
     6661 gacccttttc ttgggcggca aggaaaaaac gacgctcaaa gaaatatcgg aaatcttagg
     6721 caaagaaacg attgacagct tcaacacttc cgaaaccaga gggcgggagc tttcgcatgg
     6781 gctgaactat cagaagttag gcaaagagct tatgacgcag gacgaaatcg cggtcatgga
     6841 cggcgggaaa tgtatcttgc agcttagagg tgtgcgcccg ttcttctctg ataagtacga
     6901 catcacgaag cacccgaaat acaagtacct gtccgacgca gacccgaaaa acgcctttga
     6961 catggaaaag catatcaaac gccgccccgc tatcgtaaag ccggacgaag tatttgacta
     7021 ctacgaaatc gacgtacagg aggacgcagc accgtaaagg gaggtggtaa tctatccgaa
     7081 ctgtaaacac gggctatatg gtacgcgccc ctacttggag cgtggcagga agccgcagcg
     7141 tatcaaccct tacaaaaatg acaactgaat accgccgcgc cgcagcagtt taagcagcgc
     7201 gaggacgcag ccgccgaaca caggcggctt ttttcatacc caaaaccaaa aacaaacaat
     7261 ttttatcgcc gcaaagcggc agaaagtgag gatattatat ggcatttttc aacagcgcag
     7321 taaacgtatt gcagaccctt gttatcgctc ttggagcagg cttaggcatt tggggcgtta
     7381 tcaatcttct ggagggatat ggtaacgaca atccgggtgc gaatgctcat gtacggtaaa
     7441 gtatcacaag aaaattatgt cgaattgaca gccgcctccg ctataccgaa taaggaaata
     7501 aagagtcctc aaattttgcg ctactaaatg aagacgagcg gaagtaatct cccgctcgtc
     7561 agtaaactta actatgccat atcaatcccg cttctttccc gccaccggca ctaagaacag
     7621 cgcgggcaac agcaggaaag cggtacagac cagcccccag ggtatggaca cctgctgggc
     7681 taccagcccc acaataggcc cgccgatgat ctgcccgaaa gagtccagct gtccgctggt
     7741 ggaaaagact gtggcgcgca ttttctcatc cacatggtcg ttcatccagg cggccagcac
     7801 aggctccttg atggtgcgca taagccccgc cagcaggaac accaacaaca tgaaccaaaa
     7861 gctccgcccc accgcgaaga gaaccaggca caggatatac ccggcgctgg tggacatgac
     7921 cacactggtt cggctgacag tccctttttt ctccatgcgg gcgatgagca actgagaagc
     7981 cagaatacct aagccgctgc cgataagact gataacaccg aaccaagtga cgctgttcag
     8041 cggcccgata acgggtatta ccgtgtcatc cagaaaatga gcggtggaga gccggtcaaa
     8101 gccttcactg gcaagtcccc cgcatagtgt gattgctaag agcgccagca acacaggtgc
     8161 gcctttcaca aagcccaggt tgagcttgaa caggcagaca aagtctttaa gcaagccctg
     8221 ccgttcctca atagcagggg agaagttggt ttctggcatg atgcgaacca acaccagccc
     8281 caacaacaag cacaaactgc cccccaagat gacaggcatt tgcaggttta tgtttcccag
     8341 cagtgtgccc agcaccacgc ccagaacgcc gccgatttgc cccatttgac tgccccgcag
     8401 gaacaccttg tctatgggtt tgtcctcttc ctccgaggca atccacgcct ccagagcgcc
     8461 ggtgatgaag gtatcaccgc aaccccagac aacctgggcc agcagaaccg gcgcgaacca
     8521 cggtagcgca ccctccatca gaaagcccag gccgtagagg aacattccaa tcagcaccga
     8581 gcgccgacgg ctatacaaat ccgccaccac accggtgggt atctcgaaca gaaagcagga
     8641 ggtctccaga accgtcccta ccaggacaag ctggaaagca tccagctgca ccacctccag
     8701 gtggtacacg atggaaagca ctgtggacat agaaaccgcc agggaaaaga caaatcggaa
     8761 cagcaggtag acagaatatg cctttgaatt tttagcaaac atgaagttac attctccttt
     8821 acgaatcagt gggttgtttt gtgaaacaag cccgactgcc gcgcaggaag ggcaaacttc
     8881 tcagcccttt ctaacagtga ttttagaaaa ggcctcctaa agtgcccaaa gcgccgttaa
     8941 aagacttgtt tctgtttttg cagttatacc tccgatactg aaattagaac aacatggctg
     9001 ttcttcttcg cgatattata gcaaatgggc tttgtgttgt caatgtaaag agaagcgaga
     9061 gcgagagcga gagcaagttt ctaccacggt gccaaaatcc gcaattctgc ggttttgccc
     9121 ctcgcgggaa acttgttggg gagtgccttc cccaaaccct gctatgcggc ttgcgccgct
     9181 tatccccgcc gcgctcatgc ggcaagaaag gaggtcacga ccatgcgaaa aaaatacaac
     9241 acaccccacc gcagccgcgt tgtgaaaacc cggctgaccg aagatgaata cgccgacttc
     9301 acagcgcggc ttgcgcccta tggtatcagc cagtcggaat ttctccggca ggcgatccgg
     9361 cgtaccacca tacgccccgt actccatgtg tcgtcggtca atgacgaact gctctccgct
     9421 gtcgggaagc tcgcagccga gtacggcagg atcggcggca acctcaacca gattgcccgg
     9481 tatctgaacg agtacggcgc gccctatcat gcgttgtccg gcgaggtacg cgccgccata
     9541 gccgaccttg ccgccctcaa gtatgaagtc ttaaagaaag taggtgacgc ggttggcaac
     9601 actcaaacat atcaactcta aaaacgccga ctacggagcc gccgaacaat acctgctctt
     9661 tgagcatgac gaatttacca tgaagcccgt ccttgatgaa accggcaggc ttatcccccg
     9721 cgaggactac cggctgtcta cgctgaactg cggcggggag gattttgccg ttgcgtgtat
     9781 gcgggccaat ctccgctatg agaaaaacca gcggcgggaa gatgtgaaaa gccaccacta
     9841 catcatcagc tttgacccgc gggacgggcc ggacaacggc ctgaccgtag accgggcgca
     9901 ggcgttgggg gagcaattct gtaaagaaca tttccccggc caccaagccc ttgtctgcac
     9961 ccacccggac gggcataacc acagcggcaa cattcatgtg catatcgtca taaacagcct
    10021 gcggattgag gaagtgccgt tcctgcccta catggacagg ccagccgaca cgaaagccgg
    10081 ctgcaagcac cgatgtaccg acgctgccct gcgctacttc aaatccgaag tcatggagat
    10141 gtgccaccgg gaggggcttt accaaatcga cctcttgaac ggcagcaaga accgcatcac
    10201 cgaccgggag tattgggcgc agaaaaaggg acaagccgcg ctggacaagc agaacgcccc
    10261 catgattgcc gatggtatca cgccccggca gaccaagttt gaaacgaaca aggaaaagct
    10321 gcggcagacc atacggaaag cccttgccac cgccgccagc tttgacgagt tttcctctct
    10381 gctgctgcgg gagggtgtga ccgtcaagga gagccggggg cggctgtcct atctcacgcc
    10441 ggacaggaca aagcccatca ccgcccggaa gctgggcgac gattttgacc gcaccgccgt
    10501 ccttgccgtt ttggagcaga atgccgccag agccatagaa aaggccgcag ccatacctga
    10561 atacccctgg caggagaaac gcggcataca gcccgcaaaa gcccctcaaa ccgcccccaa
    10621 acaggacgga gtgcagcggc ttgtggacat tgagcagaaa atggccgagg gcaaaggccg
    10681 gggctatgaa cgctgggcga agatacacaa tctgaagcag gccgccaaaa cgctgtccgt
    10741 ctaccagcag tacggcttta cttccccgga gcagttagaa gccgccgttg ataccgccta
    10801 tgcggaaatg cgccagacca gcggcgaact gaaagcactg gaaaccaagc tgcaagggaa
    10861 aaaggagttg cagcggcagg tgttggccta cgcccagacc aagcccgccc gcgacgggtt
    10921 gaaagcgcag aaatccgaga aagcccgcgc cgcataccgg caggcccatg agagcgattt
    10981 tatcatagcc gacgcagccg cccggtattt caaggcgcat ggcattacca agctgcccgc
    11041 ccggaaagcg ttgcaggccg agatcgagca gcttatctcc gagaaagacg gcctgtataa
    11101 cacctatcac gaacagaagc agcggttcaa ggagttgcag accgtcaagc ggaatatcaa
    11161 ccagattttg cgccgggacg agccgcaccg cagaaaggag cagagccatg agcgataacc
    11221 tgccccgcat ggactaccgc cagcaccggc gggcgcggcg gctggtacat gagtgctgta
    11281 actacgacga ggggaactgc ctgctgttag acgacgggga gccttgcgtg tgcgtccaga
    11341 gcatttccct ttccctcatg tgccgctggt tccgtgtggc tgtcctgccc cttgacgggg
    11401 agctgtccgc agccctctta taccggggga gccggaaacg gtgtgccgtc tgcggagcgg
    11461 cctttgtccc caaatccaac cgggggaaat actgccccga ctgcgccggg cgcatgaaga
    11521 aaatccgcgc cgccgagaga aagcggaaac aaaggcagag atgtcacgct ttagagcctt
    11581 tcaaacccgc ataaatcaag gcttttttcg tgggtgtcaa agggtacgcg atacatttat
    11641 ccttttcccc cggaaacggc gttctaaatg cgtacaaaca ccccaaatcc acccaaagga
    11701 ggaaccatgt cagacaaccg aaaatactac tacctcaagc tgaaagagaa ttactttgac
    11761 gaggacgcca ttgtgctgct ggaaagtatg caggacggta tcctctattc caacatcctc
    11821 ttgaaactgt acctgaaatc gctgaaaaac ggcgggaagt tgcagcttga tgaaaatatc
    11881 ccctacaccg cgcagatgat tgccaccatt acccgtcagc aagtcggcac cgtagaacgg
    11941 gccttgcaga tttttatgaa gctggggctt gtggagccgt tacagaacgg cgcactgtat
    12001 atgagcaaca ttgaactact gatcggccaa tcctctaccg agggggagcg aaaacggcgg
    12061 gcaaggctgg ctttgcagga gcagaaagcc ttgccaaagg ccggggcgga caaatgtcca
    12121 ccatgagtgg aaagccgatt gccaccgaag ccccctatgg ctatgtcaaa tccccggaca
    12181 acaaggattt ttggattatc gacgaggaag ccgccggagt tgttcgtttg atttttcgcc
    12241 tgtttctgga cggaaaaaac cgaaaccaaa ttgccgtata tctcacgcag gcgcaaatcc
    12301 caacgcccac attctacatg aaagagcgcg ggcggggaac ctgtaaaaac agggcgctca
    12361 atgaggccaa ccgctataag tggaacaaag ccaccctgac ccatatcctc acacggcagg
    12421 agtattgcgg tgatgttgtc aacttcaaga ccacaaagca cttccgcgac aagcggaacc
    12481 actatgtaga ccggagccaa tggcagataa ccgaaaatgt gcatgagccg attattgacc
    12541 gcaccgactt tgaaaccgta cagcggattt tggaaaatgc gcccgtcaaa cgccccaacg
    12601 gggacgggga aatccaccct ttgtcgggct tgcttttctg taaggattgc ggtgcgaaaa
    12661 tgcacattcg catagattat cggaatggcg gcaagcgtca tgttgcctat tgcagcgagt
    12721 accacaaggg aaaagccaaa aaccccaaat gcaattcccc gcacatcatt gacgcggatt
    12781 tgctcatgca gaccatcgcg gaagtgctga agaaaatcga ggactattct atcagcaact
    12841 gggcggaatt tgaagcctta gtgaaaaaga accttgccat gcagcagacc gacaagacca
    12901 agaaacagca gaagcgtatc ccgcaaatca cgacgcgcct tgaacagatt gacaaggtgc
    12961 tgaacaagct ctatgaggac aacgccctcg gcacgatccc gcaagaccgc tatgagcaaa
    13021 tgtcgcagaa gtattcagaa gaatactatg cgctgaaagc ggagcttgcc gagctgcaag
    13081 agcagctatc cgcttttgag aacgcgggcg gacgggcgca gaagtttttg aagctgacgg
    13141 aacgctacgc tgcctttacc gacctgaccc ccgccattct caacgagttt atcagccgga
    13201 ttgaagtgca tgagcgcgac aagaaaaggg caaaacaagc cattcagcac atcgggatat
    13261 atttcaacta tatcggcaaa tttgagaacg aagtgacaca gcttacagag ccaacggagc
    13321 aggaaatccg gcaaatgcgg gaggaaatcg aagaagccaa aaaggaaaag agccgcgcct
    13381 atcaccggca gtattcaagg gagtaccggg cgcgaaacct tgaaaagcag cgggagtatg
    13441 accgtatcaa ggcgcgggaa taccgggcaa ggagaaaggc gcagaccgcc gccgcacagc
    13501 ccgcacagta aaacagaata accgacaacc aagagggatt ttccggctac gggaagtccc
    13561 tcttttgcgc ccggagaaag gagccgccta tgacagaaca gaacgggacg cccaccgcgc
    13621 cccggaaccc cgacagtatt atcacgacgc agagaaacgg gcagactatt gttgcggagt
    13681 tatttttcaa tcacagcagc acagaaacat tccgcgacaa gctgctcaag acgatacttg
    13741 ccgacagttc gtgtttatct gcgtctgacg gtcaagagcc ggaaaaatcg gaaatcttgc
    13801 gataacagcc gccccgacga tacattccac gtccgggcgg tttttatcgt caaaaacgcc
    13861 gttttctcca agtcaagagc cggagaaaac acccgaaaaa tgcccctatt gcgtaacagg
    13921 ggcacagaaa ggagtttgca tgagaacagg gcttaccaag caggaaaaga ccaccgatat
    13981 ttggtttgac gagaaagacc cccttatcca tatccgcacc cacaacaccg ccttgaaaaa
    14041 gcgtctgctt gcatacagcc gccgttatcc ggcgatctgc cagcagactg acgcagaccc
    14101 ggaaacgggc tgcatggagt ttgacattga gaaaggccgc ttctctttcc gtctgaccgc
    14161 cccatacagc gaggaacggc gggcggtatg ccagagagag caacgtcgcc gacaggctga
    14221 aatagagttg aaatgttcat agttttgtgc tatacttttt ctaaaagcag agtaatactg
    14281 cggaattgat tggaggacaa cacaatggtt acatttatga gattaagata aaaccgcgag
    14341 ttatgttgcg gttatccgta ttgcataact cgcttattga aacagagatg taattacgga
    14401 ggaaaaacaa atgaataata atttatcacg ctttgcagac agcaaggttt attttcaatg
    14461 cccaatttgc acaaaatcaa tggatataca aggcaatagc ctaatttgta gacatggaca
    14521 ttgctttgat atttcaagat atgggtatgt aaatttgttg ttaaaatcat cgcccaaaac
    14581 caactacagc aagcggtctt ttgacaaccg gcaccaaatt ttggagtatg gcatgtatga
    14641 tgttgtgttg gagaaaatca tacagtttat ttctgatacg ccatctataa gaaacatttt
    14701 agatgttggt tgcggcgagg gtttctatgc aaggcagata cagcaaagaa cagaacgaaa
    14761 catctttgcc tttgacttgt caagggaggc aatacagatt gcatcaaaaa aagacaagcg
    14821 caaagcagtg aagtggtttg ttactgactt atcaaaaatc cctttgaaag acggaagtat
    14881 ggattgtatt ttagacatat tttcgcctgc acactacaaa gaatttcagc gattgctatc
    14941 tcctaacgga tatgttgtga aagtaattcc tacgaaaaat catttgaggg aaatcaggac
    15001 taaagtgcaa gcacacttga aaaatccaga ttattcaaat gagtctgtcg ttgaatattt
    15061 tgagaaatat cttaaaacca tttcaagaga aacggtttca gccaccgtac agttgtcatc
    15121 agaacaaaga atgtcgttta ttgaaatgac gccgcttctc ttttgcgttg aaaaagattg
    15181 cgttgattgg cgtactctca cacatttgac aatcgaagct gatgttttaa taggaatgta
    15241 ttaaagggcg tattgatatt taatattccc atttattgag cagaacggag taaaccaaac
    15301 accctaatca aaaggacagc cgaggaaatc gactgtcctt tttctatgcc gacaggtaga
    15361 aaggagtgac cacccatgac gaaaccgaga gaaaaaaacg cgaggaattg caagccgaga
    15421 ttgaggacgg gaagaagaaa atccggcagc ttgaaaatcg ggaaaaggtg ttgcggcaaa
    15481 agttatccca agaggaacgc aggacgcgca gccatcggct gatcgtccgg ggtgcggtct
    15541 ttgagagcat tgtgccagaa gcaaagacca tgaccgacga agaagccgcc gcctttctcc
    15601 ggcttgccct gacgagcgag gaagcgcggg gctatctgaa aaaacgcacc gagggcggga
    15661 aaagcgaata atccctttgg tacaaagggc gcacttatac acccttacgg gtgcgtgcgc
    15721 tctgccgagg gcttgtcggc acagagagaa agccgcttgc ttccctctct gaccgacatt
    15781 ggcggctttg ccgcaacaag gggctgcacc ccttgcgccg cttacgcggc tatccctgca
    15841 cacccacaaa aacagtatac ccgcctttgg cgtctgtacc atttttgcgg gttttcattt
    15901 tatccgggag gtgataccca tagccatcta tcattgtaat atcagcattg tcagccgggg
    15961 caagggcaaa tcagccgttg ccgcagccgc ctaccgaagc ggcgaaaagc tgacaaatga
    16021 gtgggacgga atgacacacg actacacccg caaaggcggt gttgtccata cggaaattat
    16081 gctgccaccc cacgccccgc cctctttctc tgaccgttca accttgtgga acagcgtgga
    16141 gctttacgag aaagccggga acgcccagct tgccagagag attgacgcgg cgctccccat
    16201 agagttatcc agagaggaac aaatccgact tgtccgggaa tactgttcct ctcaatttgt
    16261 ttccagagga atgtgcgttg attatgccat tcacgacacc ggcaagggca atccccattg
    16321 tcacatcatg cttaccatgc gcccccttga cgagcgcggc gcatgggcgg caaagtccca
    16381 aaaggaatat gaccttgatg aaaacggcga gcgtatccgc ttgccaagcg gcagatacaa
    16441 gacgcacaaa gttgacctga ccggctggaa cgacaagggc aacgccctct tgtggcgtaa
    16501 ggcatgggcg gatatttcaa acgcctacct tgaacgagcc ggaagcccgg agcgtatcga
    16561 ccaccgcagc aacgccgagc gcggcattgg cgagataccc accgtccaca tgggcgtggc
    16621 ggcttgccag atggagaaga aaggtattgc caccgagaaa ggcgaactga accggaatat
    16681 ccaaaaggca aaccgcctta tacgggaaat ccgagcgcag attggaaagc tcaaagaatg
    16741 gattgccgac ctgttcaaag cgtgggaaac cgccccggaa cagccgcaac aatcccccgg
    16801 ccttgcaaat ctgctgatga agtatttgag cgttcagaga gaaaagagcc ggaagtattc
    16861 gcagcgttgg caacaacagc acacagccga tgaactgaaa accatagcgg cagcggtcaa
    16921 ctatctgacc gagcatggta tctctaccct tgatgagctg gacgcagccc tttcctctgt
    16981 cagcgaacag gccgacacta tccgggcagg aatgaaaacc gccgaggaac gcatgaagaa
    17041 gctgcaaaag ctgattgaat acgggaagaa ctacaccgag tacaagcccg ttcacgatga
    17101 gctgaaaaag ctgcaaaacg gctggacaaa caagcgcgac aagtacgagg aagcccaccg
    17161 cgccgagttg accctatgga acgcagcaag ccgctatctc catgcaaatc tgccgaaagg
    17221 aacaaagacc ttgcctattg cggaatggga acaggaatat gccgacctca aaacacagag
    17281 ggacagcgat tatgccaaac tgaaagatac ccgcgccgat gtttccgaac ttcaaaaaat
    17341 ccgcaaatgc gtggatattg cactccgcgc cgaccagccg gagcagacac agacccgcac
    17401 aaagcggcac gacatagacc gatgaaagga gtgagttttt tgtactacac ccaagaacag
    17461 atagaccggg cgaaccaagc cgaccttgtt ttgttcctgc aatcgcaggg ggaaccgctg
    17521 gaacgcgccg gacaggaata ccgatggaaa cggcacgaca gcttgaccgt ccggggcaac
    17581 aagtggtatc gccacagcca gagcaagggc ggcggcccca ttgattttgt catggagttt
    17641 tttggcaaga gttttaccga agccgttgaa cttctcacag gagaaaaggg agccgcaccg
    17701 ccgccggata gaccaagctc cgcgcccctc tccgacttcc ggctaccgcc ccgcagcccc
    17761 gacaaccgaa cagcgaggaa ctacctcaca gccgcccgcc gcattgatga agatgtgacg
    17821 ggctttttct ttgccagcgg cgatatttac gaggacgcag cccaccacaa cgccgtattt
    17881 gtggggcggg acgaggacgg aataccgcgc tacgcccaca gcaagggaac ggcgggaaac
    17941 ttccgccttg atgtgaaagg cagcgacaaa gcctttaact tctgctaccg gggcgagggc
    18001 gaaagagtgt ttgtctttga agcccccgtt gacctgcttt ctttcctctg cctgttcaaa
    18061 aaggattggc agaagcaaag ctacctgtca ttgggcggcg tgggagaaaa agccctgctc
    18121 cgctttctct ctgaccgtcc gaacatcaag accgtttatc tctgccttga cagcgacgaa
    18181 gccggaaacg acgcttgcag ccgccttgtg aagctcatgc cggagggcta caccgtccac
    18241 cggcttatcc ctcttttcaa ggattggaac gaggtattgc agcaccgggc agaaatcaca
    18301 gacgggaagt atttgcgaga agcggtctac ggcttgaaag agccgccgca ggaagaaacc
    18361 gttgagatta tccgcatgag cgaggtggac acgcagaccg tcgaatggtt atgggagccg
    18421 tatatcccct ttgggaaagt aaccattgtg cagggcaacc ccggcgaggg caagaccacc
    18481 tttgccctac gccttgccgc cgcttgtacc aaccgcaagc cgttccccca catggcagtg
    18541 catgagccgt tcaatgtgat ttaccagact gccgaggacg gtttgggcga caccatcaag
    18601 ccccgcctta tggaagccga agcagacctt gaccgcattc ttgtcattga cgagagcaag
    18661 caggggcttt ccctgtccga tgagcgcata gagagagcta tccgacagac cggggcgcgg
    18721 ctgattatcc ttgaccccat acaggcgtat gtgggcgaga aaaccgacat gaacaaggcc
    18781 aacgagatac gccccatgtt ccgccgcctt gccgagattg ccgagcgtac cgggtgcgcc
    18841 gttatcctaa tcggacacct caacaaagcc gccggaggac agagcgccta ccggggttta
    18901 ggctccatcg acttccgcgc cgcagcaagg agcgtcctgc tgatcgggcg cgtgaaacgg
    18961 gaaccgaatg tgcgcgttat cgtccatgac aaatcttctc ttgcgccgga gggtaagccc
    19021 atagcctttt gccttgaccc ggaaacgggc ttttcgtgga taggcgagta tgacattacc
    19081 gccgacgagc tgctgtccgg cgcgggcggc aacaccgcca ccaagaccga acaggcggaa
    19141 cggctgatac ttgacctgct tgcagacggg aaagagcttg ccagcgagga ccttgtaaag
    19201 gccgcagccg aagccggaat atccgagagg acggtacaga acgccaagcg caacatgggc
    19261 ggtgttttgg gcgcaaggcg cgtcggcggt caatggtaca acttcatcaa gaagaagcag
    19321 ccgcccgaac ccgcaagctg aaaacgcaaa gtgcagaccc tttgcgcttt gcactttcgc
    19381 gctttcgcct tgattgtgcg tcaataactc caaataacac ttgacaaaac gcttcatggg
    19441 gaaacgccga agatataaag ccctaccccc tcattgaaga atggggctgg aacagggacg
    19501 attgtatccg ggaaatcaaa gcggcaggat tgccgcagcc gggtaaatcg tcctgtttct
    19561 tttgtccgag catgaagaaa caagagattt tatatctcaa agaacactat cccgatctat
    19621 ttaaccgggc ggcgactttg gaagaaaacg ctatgcccta tcttaaaacc gttaagggat
    19681 tggggcgcag ctattcatgg aaagaacagt ttggaaagga gtaaatgact atggcgaaca
    19741 cgaaacttga ccgtatcgaa agggatattg agaaaacgag ggcaaaaatc cttgaacagc
    19801 aaaagaagct gaaagacctt gaagcgcaga aagtcgagga agaaaacgcg cagatcgtgc
    19861 aaatggtaaa ggcggtacac cttgacggga cgcagcttgc cgcgttcctc tccgcttacg
    19921 ccagcggcga aatcaccttg ccgcagccgg aagccactta ccccgccgaa caggaggaca
    19981 acgacaatga agaataaaaa gataatccga aagtttaccg tattgcttgc cgcactggtt
    20041 atcatgtgcg gcttttctgt taccgcttat gcgggcggtg gcgatgaaag cgacgacacg
    20101 cctacccccg taaccgagga aacccccgcg ccggaaaccg agccggaaga aacgacgggc
    20161 ggctatgagc cgcagcccct taccccggac gggaatatgt cccttgtgga cgatataacg
    20221 ggtgaagcgt ccggcgacaa gcagtttatc accgtcgtta ccaaaagtgg caactatttt
    20281 tacatcatca ttgaccgcgc cgaggacggg gaaaataccg tccatttcct taaccaagtg
    20341 gacgaagcgg atttaaccgc ccttatggag gacgggcaga ccgaagcccc cgtttgtagc
    20401 tgcaccgata aatgcgttgc cggaagcgtc aacaccgctt gcccggtttg cagcgtcaac
    20461 atgagcgagt gcgcgggtgt ggaagccgag ccggagccgg aagaaaccga gcagccgccg
    20521 gaagaagaaa aaggcggcgg catgggtatt ctgcttgtcg tgctgcttgt tgccgcagcg
    20581 ggcggcggcg cgttctacta ctttaagatt ttgaagccca aaaaggacgc ggcgaaaggc
    20641 agcagcagcc ttgacgacct tgattttgac gaggacgacg aggaaacgga agtagtcgaa
    20701 accgaacaga ccgagcagga ggacgataat ctatgaaact tgtaattgca gaaaaaccga
    20761 gcgtcggggc ggcgattgcc gccgttatgg gcgcgaatga aaagcgcagc ggatattttg
    20821 agggcggcgg ctaccttgtg tcgtggtgta tcgggcattt gattagcctt gcagacgcgg
    20881 cgacctacaa tgaacaattc cgtaaatgga agtacgacga tcttcccatt gtcccgcagg
    20941 agtggcagtt tattgttgcc agcggcaagg agcagcagtt ttccattctc aaagacctta
    21001 tgcaccgcag cgacgttacc gagattatca atgcttgcga cagcgggcgc gagggggaac
    21061 tcattttccg ctttgtctat gaacaggcga attgcaaaaa gcccttttcc cgcctttgga
    21121 ttagcagcat ggaagcaagt gcaatccgcg agggcttttc aaatctcaaa gacgggcgcg
    21181 gctatgacaa cctctatcaa tccgcgcttt gcagagcaaa ggccgattgg ctcattggca
    21241 ttaacgcgac ccgccttttc tctatcctct accataaaac attgaatgtc ggcagagtgc
    21301 aaacgcccac ccttgctatg ctggtaaacc gcgactatgc aatcagcagc tttaagaaag
    21361 agaaatatca tgtcgtccgg ctggacgttg gcggcgttgc cgccctttcc gaaaggcagg
    21421 acgacgaagc ggcggcgcgg cagatgaaag cggcttgcga gaaatcgcag gccgtttgta
    21481 cttcccttaa aaaagagaaa aagaccgcag ccccgccgaa actgtttgac ctcaccgcct
    21541 tgcagcggga agcaaaccgt ttgtatgggt ttacggcgaa acagaccctt gactatgcgc
    21601 aagcccttta tgaaaaacgg cttttgacct atccccgcac cgacagcaaa tatatcactt
    21661 ccgatatgga gggcagcaca aaggaactta tcaccggcct ttgcgctgct ctccccttta
    21721 tgcagggcgt gaagctgcaa gccgaccttg cgaggatttg cgacaacagc aaagtaaccg
    21781 accatcacgc cattttgccg acagcggagt ttgtgaaaac gggcttttct tcccttgccg
    21841 aaagtgagaa aaagctaatg acccttgtgt gcgcaaaact gctttgcgcc gttgccgcgc
    21901 cctatgagta tgaagcggtt acggcggttt tcacttgcgg cggctatacc tttaccgcaa
    21961 agggcaggac gacgctttgc gagggttggc gcgagattga aagactatcc cgcgccgcgt
    22021 ccggggaaca ggacgaggac gcagagccgg aagcggtttt acccccgctt gccgaggggc
    22081 agacctttga caatccggca gcggagatct ccgaacgtta cacgcagccc ccaaaggcat
    22141 ttaccgaaga tacgttactt tcggctatgg agagtgcggg aaaggaggac acgccggagg
    22201 acgcggagcg caaagggtta ggcaccaccg cgacgcgggc gggtatcatt gaaaaactca
    22261 ttagcgcggg ctttgccgag cgcaagggca aaaagctaat ccccacaaag gacgggtata
    22321 accttgtcgc tattctgccc gacagcctta cgtccccgca gcttacggca gaatgggaaa
    22381 cgcgccttac cgggattgca aagggcagcg acagccccgc cgacttcatg cgcgggattg
    22441 aggaaatgac agcggggctt gtcaagacct attccgcgat ttccgaggat aaagcgaagc
    22501 tgtttacccc gcagcgggaa gcaatcggca cttgcccccg ttgcggcgcg gcggtttacg
    22561 agggcaagaa aaacttttac tgctccgaca gggcttgcag ctttgtgatg tggaagaatg
    22621 accgcttttt tgagcagcgc aaaaaggctt tcacaaaggc gattgccgcc gcccttttga
    22681 aagacggaaa ggtaaaaatc aaaggtatgt actcgaccaa gacgggaaag acctttgacg
    22741 gagttgtgct gcttgccgac acaggcggca agtatgtaaa cttccgcgtc gagcagaacc
    22801 gaaaatgata aggcttgatg aaaagcaata ccgcgccgta aagaaaatga cccgcgccgc
    22861 ttgtgcaaac aacgattgcg ggaattgtct gctgctggac gacggggaaa cttgcgtttg
    22921 tgtgcagagt atcagctatt cgctgctatg ccgctatttc cgcgaagcgg tattacccgc
    22981 cgacaggcag ctttgcgaac agatcacccg cagcggggaa accgatttga agcgttgcgc
    23041 ggtatgcggc agcacgtttg cggcgggcag caaccgggcg aaatactgcc ccgattgcgc
    23101 ggcaaagata cgccgcagac agaaagccca aagcgagaga aacaggcgtt tacggataaa
    23161 aacaactaca tagcaagcac agcaaacgag tacccgtttg cgagaaatgc ccgcgcttcc
    23221 catagagagc gcgggcattt tgcttgttgg gatagtccca aacccttata tgaccgagaa
    23281 aggacgtgat gaaagaatat gccgtattcc tcatacgacc atgacaaatt agaagccgcc
    23341 gaaaccatgc ggatagaacg ccggatatat tttgaagcaa aggacaggga gattgcccct
    23401 tatgcttcct tgccgattgc gcagctactt tccatgcgca gcgaaagcgc ggcggcagaa
    23461 caggcgattt ttgacgacct taaagaacgc gccgccgcat gggaagaaca ggcgggaaga
    23521 acgcttttgc tggataaaac acttgaatat gtgagaacgc cgcacgtcca gcacaccgct
    23581 aacgagtggc agaccaccga gcataaccgc catattcgca gcaatcgggt atatcagatg
    23641 aattactaca tttacgagaa tacccgctac gacaaagaag cgcagaaatc tatcccgtat
    23701 tcatggacgc ttacatggag cgtgcgcacc aacagcccaa gcagaaccca agcgaagatt
    23761 gccggacaag atagaaaggt tttcaccgac aaggcagcta tggaaaagta tctgaatggg
    23821 cgtatcaaag cgtatgaccg cttgtttacg gaaatctccc cgcctatccc gcaggagtac
    23881 gccgactatt tcaaagtaaa cggtatgctc atgccggact acaccataga gggcgaagaa
    23941 cccccgcagc agcaacaggc ggcagctatc cccgaaaata ccgggcagga aaaggagcgt
    24001 gaacacatga gcgaacagtt ttctattatg ataggcaacc gcagccgctt tgacgcgggc
    24061 gaccccggcg gctattggtt ggatatgccc gccacaaagg agcagttgca cgaagctatg
    24121 cggaacgtcg gcattaccgc cgacaacccg caggattttt ccattcgcgg ctattccgac
    24181 gacccggaga aacatattgc cttgccttat gaaatggtat gcgccgccga cgtggacgaa
    24241 ctcaattttc ttgcggcgcg gctcgaacag cttgaccccg ccgaggttgg caagctgaac
    24301 gcagctttgc agcagaaaaa cgggcttgca aatattggac aggtaattga cttcacctac
    24361 aacgtggatt tttacgtcca tatccccgaa gtacataact accacgattt gggcgactat
    24421 tacttaaatc aatccggcat ggtacaaatg cccgaagaat ggaaaggcgg cattgacctt
    24481 tctacttttg gcaggaacgc tgccgcgcag gaaaaaggcg cgtttaccga gtacggctat
    24541 atcgtggaaa gcggcgacga gtgggaacgg cagtttgagg ggcgcgaagt gccggaagaa
    24601 taccgcatta tgagttaccc gcagccggag cgcggcgaac aggacaaagc ctatatggac
    24661 gcagccgaaa cgcagcaagc agacgcacag gccgcagagc cgcagcagcc ccgccccgtc
    24721 gtccccatta tccttacttc cgaaaagccc gccgaaaagg taaaggagat caccgcgcgt
    24781 ttggaacagg gcgtacaggc gatttttgac agcgaccgct acaaagagtt tctaaccgct
    24841 atgtcaaagt tccatgatta tagtttgaat aacactatcc taattgctat gcagggcggc
    24901 aatttggtaa tgggcttccg tcaatgggaa aaggagtttg accgccatgt aaagaaaggc
    24961 gagaaaggca ttaaaatctt tgcccccgcg ccctacaagg tgaaaaagct ggttgataaa
    25021 atcgaccccg aaacgagaaa gcccatgctt gaccgcgagg gaaaagtggt aaaggaagaa
    25081 aaggaaatca ccgtccccgc ctttaaggtt ataaccgtct ttgatatttc gcagaccgag
    25141 ggcaaggagt ttcccgacct ttccgttaaa ccgctgcttg ccgatgtgga gcagtacgag
    25201 gattttttcg ccgcccttga aaaagcgtcc cccgtcccga ttgcatttga gcagatcaca
    25261 aacggcgcaa atgggtattt cagtttgacc gacaagcgta ttgcaatcaa agagggcgtg
    25321 agtgaattac aggcggtaaa gaccgccatt cacgaaatcg cccatgcgaa gctgcacgac
    25381 gtagacttaa acgccccgcc ggagcagcaa aaccgcgttg accgccatac ctgcgaggta
    25441 gaagcggaaa gcgtcgctta tacggtttgc cagcatttcg gccttgatac ttccgattac
    25501 tctttcggct atgtggctgg ttggagcagc ggcaaggaaa tgaccgagtt aaaagcgtcc
    25561 cttgaaacaa tacagaccac cgcaaaggaa ctcattaccg agattgaggg gcattttacc
    25621 gagttgcagc agcagcggca agccgagcag gagcagggcg ataccttttc catttatcag
    25681 ttaaagcgcg gggacgaaac aagggacttg cgctttgagc cttatgaccg tctgcaagcg
    25741 gctggactta ccattgaccg ggtaaattat gaactcgtct atactgcacc gcttacaaag
    25801 gatatgacgc tgggcgacat ttgggaaagg tttaatatcg accaccccgc cgactttaag
    25861 gggcatagcc tttccgtttc cgacattgtt gtgcttcatc agaacgacga ggacaccgcc
    25921 cactatgtag acagtatcgg ttttcagcaa gtgccggagt ttttgcagga gcagcagacc
    25981 cccgtatttg acaagctgcc gcccgaacag cagcaagcct tgtccgacac cgtacaagac
    26041 actttgcaaa tgctggttga cgcagacaag cggatttatg gcgacgttac gggcaagacc
    26101 cttgaagcaa tcgcggcgca aggatattcc tacaaggacg ggcagcttga aaagcagcag
    26161 ccggaagcga cccccgacag ccttttgacg ggtgaaaccg ttagaacgcc gaggggcaat
    26221 tttcatatta ccgatatgag ccgtgaacag atcgaagcgg cgggatttgg ttttcaccat
    26281 gcgtcggagg acgggaagta tctcattatg gggaatggca cacaggctta tgccatagcc
    26341 gccgagcagc cgcagcggga taatccctta aagcacgtcg aggacaccat agagcagaac
    26401 gacaacaatt ttgacgggct tatcaacaat acgccgcaaa cgcccaccgt tgcagatttt
    26461 gagcagcggg caaaggcggg ggaagcgatt tccgttaccg accttgcaaa agcggtaaaa
    26521 gccgagaaac gggaacagcc gcagaaaaaa ccgtccattt tgaagaagct ggacgaatac
    26581 aagaaacagg cggcgcagca gccgaaagat aaacagaaag agcataaaaa ggatttggag
    26641 gtttgatagc atgaataccc gctttaccat tgaggaagaa aacattgttg cgatctacgc
    26701 cgaggacagc cgggaaacaa cgcttgaaaa tatccttgcc gccatgccct acatggacga
    26761 ggatatgcgc cagcttgccg ccgcagcggt gaacaagctg caagccatga cggacagcga
    26821 gttttccgaa agggagttta tcttgaccga cgaggaatag cccatagaga acaggggcgc
    26881 ggttgccgat ttccggcacc gcgcccctgt tctttttttg tccttgcgtg gacaattaga
    26941 aagccgtttt tgcgggtttg aatatacttt atcgtctatg tcgttttcat gcgctggaag
    27001 ccgcagaaac acaggcgttt tcagccctta acattccact tgccacccca tgttttgcgc
    27061 cttatcgctc ctgctcccgc gccctgcttt gggacgggta aagaatacta tcgacgttct
    27121 ttttgacaac gccgtattcc tgcatttgct tcttggcttg ccgataatct tcatacaatt
    27181 tggttttcct gtcgtttaag cttctatact ccttgcgcag cgcggcgaga tcgggcagct
    27241 tctttatctg catttccttt aatgcccttg ccgcagcttc aaacaggata atttcgcttt
    27301 catgcccccg cagatacttt tccttgtccg gcgattttcg gtattcatcg taaatcggtt
    27361 ttaactgtcg gtatgtggtg gtgtgcttga taagcagcga caaatcagac atacgctgtt
    27421 ccacttcctt aaccgccttt gccgccgcgt catgagcggt cataatatcg gctatcttgc
    27481 tttcaagttc gctataatac tcaatcttgt tttcggttag gaagttcatg cttttagcag
    27541 cctgtttcag attatggatt tttgcccacc gttcatagcc cgccgactgt tgggctttga
    27601 tactgttttc aagatcgacg acaagccgga ttttcttatc ttcccgcagc gtttttgttt
    27661 tggcaacata cacgcccttg atacgctcct ttatcgcttc ttccgtatag gccgcgccga
    27721 gcgtctttgt gcgggtaaac cgttcctgtc cggcagcgcg aaaggaaatg tatttgccct
    27781 gtttgatttc ataccccatt tcctgcaagc ggcgcagcag ttcgtcaaaa tctttcactt
    27841 ggggaatgag agtatctatc gccgttttca gctttgcttt gtagcttgtc ccttgctttt
    27901 cggcggtgta ttctgcatag ctttttccct tgtcctgtcc cggtacgacg acggatagcc
    27961 catgctcttt acatatcctg tcgctggtgc gccggataaa gtgatagctt tgcttgttgg
    28021 aatggtactt tttgtagtca acgaagctaa ccgcgttgaa aatcaagtga ttatgcagat
    28081 ggtctttatc gacgtgagtt gtcaaaacaa actcatactt gccgcctaat accgccccgg
    28141 caagttccat gccgattttg tgcgcttctt ccggtgtggt ttctcccacc gcaaaggatt
    28201 gtatcaagtg ccgccctaaa tgtgtgccgc gatctccggc agcttcccgc gtccatgcaa
    28261 actcaatatc ggcggtttcc agcccgcagc cgaaagagga cgcaagcagc ttcccgtctg
    28321 tcttttcggg atttaagata tagtctatcg cagcctttaa ggttgattta atagggtgcg
    28381 tctttgtaac cgccatatct cgtccaccgc ctttttaatg tcctctatat cctgcctgta
    28441 aaccgtcccc gtcgcattgg cgcgttttgc aatttggttg atgttccggc tcaccgcttg
    28501 cagttcccgg atatatgctt ttgtgtcgct tcggtcaacg acaagaatat acccgtctat
    28561 cgccatttta cggaagtatg ccccatactg ctttatggga agctgcttca tcttctcgtc
    28621 gatcagccgc ttttcttctt ccgtaacgta aaacttcatc tgtatatttc tctttcggtt
    28681 ttccatttcc gcaccgcctt tcggtataag ggtttgggat tatcccaaca agcattttcc
    28741 gcaaacgggt actcgtttgc tgtgcttgct atctactcca tacccccacc gaaaggcggt
    28801 atttgttgcg cgttcctttg attttggacg caaaaaaaga ttgcagccgc catgcgctgc
    28861 aatctcccga tttctcatat tgtgaggtta atcctctgct ttttcgactt ccgttatctc
    28921 ccttgctgtt gcggttacaa tccgtatgcc tttatcgctc ataccgtcca gcagcgcgtc
    28981 aagctgccgc cgcccggtgg atttctccgc attgctgttc gggaagaaaa attgatctac
    29041 cgaaatatga taccgggtta caaggtcata gaatacctgt aaactcggct gttgtccctt
    29101 gttctcgata ttcgcaaggt agcgcgggga aatatataac tcgtcgctta cctttttgcg
    29161 gctctcgccg tattcatttc tcgcggcttt tatagctgcc ccgaaagcct taaagtcgta
    29221 caatggtacg ggtctttttg ccattttcat tcaccctgtt acattttaca gttcaccttt
    29281 ctttttggat atgtccacac aattcatatc attaggttaa atacttcctg ttgtgtattg
    29341 acagtagact gattttctga taaaataaaa tttatgtaaa aggaggcggc gtttatgttg
    29401 catagcatgc gtattagata agcattgaaa aaaaggattt tcccattttc aacatgggct
    29461 tttttgtcat gcttattttg cggatgctat acaaaaaact aacgacgtat agatatagta
    29521 tagacatagt gcaagctatg ccttagtttt gttgtactgc tctgtgcatt tttttgtgta
    29581 aaaaggacga gtgaaatata atgcttaaaa aatattggat aaaatgtccg atttgtaacg
    29641 gaaagacgag agttcaagta tttcataata ctgtattaaa agattttcct cttttctgcc
    29701 ctaaatgcaa attgacgcat atcattgatg tagaaaaatt agagattgta atcaaaaata
    29761 cagaaaaaca aacttttatt atttagaaga aaggatataa aaatgaaacg tttacctaaa
    29821 tatacgcctg cggaagtacg gaatgatcca tacggattta cttacaaaga aatgtcggaa
    29881 gttattggcg agaatgaagc aaaagcctta tatgaagaat tatataagca attaccacgc
    29941 aaaaaaaatc tatcaatgtt ggtaaaaaat atttgcaaaa gcagtgatac tgaaaagtat
    30001 gtttacgaac tgaaagacaa caaatacatt gaaacggttt ttatcaagcg gcgagatggt
    30061 ggaactgttt gcgtgagcac acaagtcggt tgtcctgttg gttgtatttt ttgtgagtcc
    30121 gggcgaaatg gctttgttcg taatctaaca tcgtcagaaa tcgtacaaca gattatattg
    30181 ttgcgtcgaa aagtaaaccg tatcgttttt atgggtatgg gagagccttt attcaattat
    30241 gacaacttga taaaagcaat ccatattctc cgagatagat atgggctcaa ctttccaacc
    30301 gacggcatta ccatatcaac agttggtccg gtcgatcaat taaaaaaatt gcgcgaggaa
    30361 catcttaaaa ttcagttgac aatatcttta cacgcagcaa cacaatctgc aagaaatcgt
    30421 attattcctc acatgcgcat atatgctatt gaagatgttg ttaagcaagc cttatcctat
    30481 tctgaaaggc ataatcgcaa aattgtcttt gcgtatttgc ttttaccggg tataaatgac
    30541 cggccctcag atgtaagaca acttgcaaaa tggtttcggg gcaaaaaagt tatgattaac
    30601 gtgttacaat acaacccaac aagcaattca agaattaaag caccacagaa acgggaaata
    30661 gttgcattca aacatcaatt agagcaagca ggacttgaag ttactatgag agtttctcat
    30721 ggcagagaga ttaacgcggc ttgtggacag ttagctaaca catataataa attcaaaaaa
    30781 aaatgattaa aagtgccaga cgcatagacg cagagccgat aacgcattag gtcaaaaaac
    30841 ctatgtgtta tcggcttttt tatttaatat tgcgcaaaag ccgctgttcc ctattataga
    30901 atggattgcg ggtagtgtat taaagtcgcc cttttttaag gatacggcgg tatcggggag
    30961 gtatcgccgt gtccattttt atttactgta acccgcctaa tgctttgcgg tcaaaaaaag
    31021 ctatgctccg caagcgggat attccggcta tgaatgtgaa ctgtcaatac atttagctac
    31081 tgcttacatt tcctttgcgc ccgtccgcgt cttgcggacg ggcgcatttt gcttttttca
    31141 acttttttct gaaaagcgca ctcaagagcc atctcccgaa cgggtacgga gcgaaagggg
    31201 cagagaggac aagcccttaa ctcccgtcct ctactccacg cgggaaggag gtgaactcta
    31261 tggagctatc ttccagcggc ccggatttca agccatgctt gcggacattg aagccgggaa
    31321 agttggtacg gtcattgtca aggacatgag ccggttaggg cgaaactact tgcaggtagg
    31381 gttttacacg gaaatgctgt tccctcaaaa gggcgtgcgt tttatcgctg tcaacgacaa
    31441 tgtggacagc gcaaacggcg gcatggacaa tgattttacc cctctgcgaa atctgttcaa
    31501 cgaatggctg gtgagagata cgagcaagaa aatcaaggca gttaaaagag caaaaggcat
    31561 gagcggcaag cccgttacca gcaagccggt gtatggctac ctcatggacg aggacgagaa
    31621 ctatatcgtt gacgaggaaa ccgcgccggt tgtccagcag atttaccagc tttgccttgc
    31681 ggggaacggc ccgaccaaga ttgcccgtat gctgacggaa cagcaaatcc ccacgccggg
    31741 gacgctggaa taccgcagga caggcagcac acgccgctac caccccggct atgagtgtaa
    31801 atgggcgacg aacaccgtcg ttcatatcct cgaaaaccgg gagtacaccg gctgtctggt
    31861 aaacttcaag acggaaaagc cctcttacaa gaccaagcac agcgtagaaa atcccattga
    31921 gaagcaggcc atttttgaga accaccatga gccgattatt gacacggaaa catgggagcg
    31981 tgtgcaggag ttacgcaagc agcgcaaacg cccgaaccgc tagggtcagt gatgtacagt
    32041 gtatttgacc ttagctcatt acatatggag attattataa atcatgttcc ttttgtcggc
    32101 gttcagtaat atctttgaaa tgtgcgtcat tggatagcaa ggtgttgaaa ttggcagtta
    32161 tggtatttaa tgttgagtgc cttttttcta aatcttgctt ttccttgaca gcagaggaac
    32221 gttcatttct tagattgtca atttttttct gcagcctctc tggggaaggt aattttgtaa
    32281 tgcccagctc ctgtaattgc tgttttaagg aatcatgcag tttgtattcc gactggtgag
    32341 tagctttata tttctgagga tccggtgctg tttttgcatc ttcaattatt tttctgcagg
    32401 tacgatagga cgaacaatgc ttctgaataa gttcctgatg ggatatttca gagattaatt
    32461 cagaaattcg ctgttccgta gcaataatag aattatcaat atcagcaata tgctgcctaa
    32521 agtcttcgta attcagcaaa ttgttttcgg atagatagtt gaaggttcgg gctgcttctt
    32581 tcagattatt gagttgtgcc caccgttcaa atccggcacg attgccggta ctcacgtaag
    32641 cagagatatt gacaaaaagt cgtacttctc tggagacgtt acgtggagat tttgttttat
    32701 gccggttttt ctcaaggcgg agtaatacat tttcttccgt ataatagcta cccagagatt
    32761 tcatatttgt aaagtttttt tgctccggtg cccggaaagc caggttcttt ccctgacgga
    32821 tctcatatcc ggcaagcttc attttttgaa gaaactcatc atagttgata gaggaccaga
    32881 ttgctttgtc tacagcgact tttagttttg ctttccagct gtttccgcga tggtattcca
    32941 tattttcttt ataagatttc cctttttcgc cggttggcat actggtgacc agaccgtttt
    33001 cctgacaaat acggttgctg attcggcaga ttttatgata gctgcgtttg ttggagacat
    33061 atttatggtg gtcaacaaag ctggtagcat taaaaatgat atggttatga atatggttct
    33121 ggtcaacgtg ggtgctgatg acatattcat atttcccttt tagtacttcg tcagcaaatt
    33181 ctttgccgag cttatgtgcg gtttcagcat caacctctcc aggcttaaag gattgaatta
    33241 aatgaaatgc cagattgtta cctttgtcca tcacgttctt tttcccttct tctctggtga
    33301 aagcaaattc cagatcagca gattcagggg aacaggcgaa actggaaatc aataatttct
    33361 cttcggtctt gcccggattc ataatatagt ccagtgcttt tttgtcagtt actttaatgg
    33421 ggaagatttt aatatatgcc atatctcgtt taccatcctt ttcaattctt ccatttcttc
    33481 cgggtacaac tcaccagtgg tgtttacctt ttttgcaatt tgattgatat ttacaccgat
    33541 tttgtgcatc tcttcataca cctgcttgat cggggttgtg tcagtgttga tgatatagcc
    33601 gtcgatagcc atttttctaa ggtaggctcc catgtttctg gtctttgaca aaatcatctt
    33661 ttgacggatc agcttctttt cctctggagt aacacaaaat aaaatttgaa tgtttctttt
    33721 tctgtttgac atgtcgtttc tctctttctg tacgtaattc gattttggtt gtttctaggt
    33781 ttttaattta gggcagggtt ccctaaattg ccatttttgc ggaagtgtat atacacttcc
    33841 tgtccttgct gttataccct ctaatagata aattcagaga gaaaagaaaa atgcaaaaga
    33901 atttgagaaa ctgaacaggt agtgcagatc atgaaaatgt ggtatgatta ttgtcaagat
    33961 acgagaacat ccaagggtgt gaatagattg tggatagaga agaaatcttt gaatatgtaa
    34021 agaagcagta tggaacaata ccggaatatt tgtggagcag ttctccagat agtgcagtac
    34081 ttcgccacca aaatggaaaa tggtatgcgg tgatcatgaa tgccgaaaaa tccaaacttg
    34141 gtttgaatgg agacggtacc gtggaaatta tagatgttaa atgtgatccg gaaatgacag
    34201 gaatgattat ccagacctat ggttttctgc cgggctatca catgaataag cagcattgga
    34261 ttacgatttt gttggatgga acagtagggg aatcaaagat attggatttt ctggatatga
    34321 gttacgattt gattgatggg aaaaagtgat gatgacaagg taagagagag tattattgaa
    34381 aaggagttta tattatgaca aaagtaaata caatgaatac taagcttaca cgtggagata
    34441 aagcacacaa aaaatttata gaaaaacttg atgtttttaa agacggtctg aagcatggaa
    34501 tggattcgtt agaaatgatt cataagcaga cacttgattc gtctgtggag tttactaaag
    34561 tagtatcaaa atctcaggaa gtagaacgga ctgcacttta tgatattata aaaaaatgtg
    34621 aagatgaaac aagaagaaag gaagcttttg agcgacttgc ggaacttgat cgtattaagg
    34681 aaaaagaagt cgacactcac aatgatttcc tcaaaaatga aagagaaaaa gcaaatagaa
    34741 atattacagg tggtattctc tgtcttgcag ttgcaggtgg actcatatcc agtaaacaag
    34801 tacgacaaat gagcggaaaa gcccttacta caataagtaa aaatttactc cgaactaaag
    34861 aataaatatt ttatagttaa gtccgggata atgtttttga aatagatgag gctctgtttg
    34921 cttttgaata aaaaataata aaagggagat acaaatatgg attcaaacac tattttaagt
    34981 aatatattac aagaagaagt acaatacttt tataattgta tacgagatta tgatgaaaaa
    35041 cgcattattg atattgctat ggttgacgat gtttacgcaa aagtacttga atatgatatg
    35101 tgtgatgtac aaaaagaagc ggtaatgaag gctggtgctg cactcaatga ttcaaacggg
    35161 acagtgattt ttgcaccgtc aagagataaa acaacactgg tagtattatc taagaaggtg
    35221 ttgcctcaaa aagatcttga cgaagtgcat ggaactgtat tacatgagtt gacccatgca
    35281 cacgattatt acgattatgc ggattattta caaattagtg actataatac actttttaat
    35341 tcacaatact ataacgcatt tttcctatgg acagagtttc atgctcggag aatcggttac
    35401 aagagattta tagaatacaa attcagaaaa ggatggaaac agtttaaaaa gcacagatat
    35461 gagtttcttg aaggaattaa tgcgaatttt tcgatttata gtagcaaagg acgattatac
    35521 gatcttatgc aagcggctgg tagatattat acgtttatag aattgtgttc atcacatact
    35581 gaaaatttta aaggagatat cttagacggt aatgttgaac cggatttgct taatatatta
    35641 aatgaagtat actgtttctt ggctgagaat agagagttta aacagtttgt aaataatatt
    35701 gtaatatttg acgagttatt acataaaata gactcaatgg tcagtgagca aattgaacaa
    35761 gtataaaaca tagaaagtta gtattttata aacgaaactt taaaaaaaga acgcttgtta
    35821 gtatatcatt actgtctcaa ttaatttggt gattaatatg ataaggattt aaggcaatag
    35881 aaaaaccggg gattactcct cggttttttt ctggctggaa gttccatcgt ccaatttgaa
    35941 tatttcttcc acactcatat tcagataatg ggcaagtcgg attgccatct ccaaagatgg
    36001 gtttcgctcc ccacgttcaa ttctgccgat ggtacggctg caggagccgg ttgcttctgc
    36061 taggtcttct tgaataagat ttcgctctat acgaatgtct ttcagaatgt tgctgattgc
    36121 catccaatca cttcctttaa ctttattatt gtttcaacag ccggtttgaa tggcacggac
    36181 tgtattacga ttattgaaaa ccgaggatgt cggaagcatc acacttgccg acaactttgc
    36241 cgaatatttt aaaagagtcc gattcctgaa ttgcgatagg tttgtatttt ttattcaggg
    36301 agatcaggaa taatccatcc ggttcatcat ggagtttttt gatgtaggca tctccattga
    36361 gatagaaaat accaacctct ccattgcaga tactgtcttt ttgctggatc catgcaattt
    36421 ccccgttgtg gtattccggt tccatactgt ctccggatat ccggactcca aagtcggcat
    36481 tgtctggagc aagatcgcct acttcatagg attcttttgg tgaatcggtt aaaaaattac
    36541 cggtacctgc agaaacggca tctccgaaga tgtccataaa tatttccttt ttacggaaag
    36601 gaataatgtt tgcaattact ggttcaaaca agccggaggc ttttagtatt tttgcgtagt
    36661 cttttatctt atcttttcct tcctgattca gaccgtccat tacactgtat ggattttttc
    36721 cgaaataagc atcataaata tcttcaatat ccaataattt acagagagtc agaaaaacat
    36781 gcagtcctgg ttctcgtgca tccgtctccc atttggagat tgccttcgct gtaacgtcaa
    36841 tgccctgctg tgaaagtaat tctgcaagtt ctggctgcga aagccctttc ttttttctgt
    36901 tttctgcaat aatcctgcca atagaacgca tatattcgcc tcatttctat gaaattccgt
    36961 tagattctta taggtgcatt atacagcaca tatacaagaa aatcaagtaa aatctccaaa
    37021 atgtagataa cacaaccaaa atgtcagttg actatctcca taatgtcggc ttatactaac
    37081 catgcaagga atgataagaa agccggacgg aggtgagaac aggatgggtg acaggacaat
    37141 tttacatagt gatatgaatt gtttttatgc cagcgtagaa atgctgcatc atccggaact
    37201 agagggaaag ccacttgctg taggtggcga tccggaagca agacatggta ttgtgttgac
    37261 ggcaaattat attgcgaaga aatgcggagt aaaaacagga atggcactct ggcaggcaaa
    37321 acaggtatgc ccggatatta tttttgtccc tccaaggatg gatctttata tcagattctc
    37381 tggaatggcg aaagaaatct atgcagaata taccgataag attgagcctt atgggattga
    37441 tgaagcttgg ttggatgtaa cagacagcag tagtatcaag ggcgatggaa tgaagattgc
    37501 acaggaaatc agcgaccgga ttaagtatga acttggtatt accgtgagta ttggcatttc
    37561 ctggaacaag atattcgcaa aacttggctc tgattataaa aagccggatg ccatcacaca
    37621 gtttcatcgt ggcaattaca aagaaatcgt ctgggggctt ccagtgtcag atttactgta
    37681 tgttggcagg cagacaaaca agaaactgca gaaactgggg atccatacca ttggccagct
    37741 ggcacagaca gatgaaaagt tgctggacag ccattttgga aaaattggtc tggtgttatg
    37801 ggcatttgca aatggatatg attcggatcc ggtttgtacg gaaggatatg aggctccggt
    37861 caagtccatt ggaaacagta caacgacacc gagagacctg gaaacagatc tggatgtttg
    37921 gattattctg atggcattat ctgagagtgt atctgccaga ttacggaaac atggttttaa
    37981 atgtaaggtg gtggaaatat caatccggga taacgggctg aacagcatca caaggcagaa
    38041 gcgtatcagc cagccgacga atattacgga tgaaattgta aaagcagcat ttgaattatt
    38101 taagaaacat tacagatggg agcatccgat acggagcctt ggcgtgaggg ggtctgatct
    38161 ggtaatggaa gatattccgg ttcagcttga tctatttgat aatcaggaga aacgggaaaa
    38221 attagaaagg ctggaccggg ctgtggatga gatcagacga cggtttggat atttcagcat
    38281 acagcgggca gcaatgtacc aggataaagt cttatcccac ttggacgccg gtacacatac
    38341 ggtccatcct cacagttatt ttcatggata atgggaggga tagatttgaa acagacatta
    38401 accagaaagc aggaagaaag ttatcagtgc attgtaaggt ttaccgagga gcatgggttt
    38461 ccgccaacgg tcagggaact gggagaatta ttgggagttg cctcaacatc aacggtgttt
    38521 tccagaatca aacagttaga gaaaagcgga tatatccgga gacttccggc atctccaaga
    38581 gcaatcgaaa tcctttgacg gaggtgcggt atgaataagg tatatgttga tgtggtagca
    38641 gaattcagta aagaaggatg cctgattcca attttatttg tttgggagga cggcagaaag
    38701 tataagattg acaagatact caagattgaa cgatgtgcca gcaggaaagc aggcggtgtt
    38761 ggtacgatgt acacttgtat ggtacagggt aaggaaagcc atttgttttt tgaagtagat
    38821 aaatggttca tggaaaggaa gatttcataa taaaaaagaa gaatattaac cggcggagat
    38881 agtcactttc cctttatatc ccgttggttt tacataagga tctgcattct gatcagccga
    38941 tgttccccac aaacatcaat tgggatatgg atcctgcaat gagtaattta gattgctttc
    39001 catcaaaatc atggggaagg cgaactggtc tgcaagacct accagttagt gtgattgttg
    39061 ataaggagaa taaaagattt atgacagaca gagattatgc aattaaatca atgaaagaga
    39121 ttacgttcca gatggcaacc catgcacaga actatctgga agtaactatg gacaggcatt
    39181 atgaagacat aaaggcattg atggtgaatt accagaaact gatattggag aataagatgg
    39241 tactggaaga actggaaatg gagtgccagg agaagatcaa tgaggatatg gcctatgcgt
    39301 tgagctatct tgatgtttac gggaaacagt tgaatgtaac gaaactgagg catgaaatga
    39361 acaatctgat ggtcatatat ggattgtcgg atatggttta ccgggggatt acactggtaa
    39421 agtattatgc accggatgga gtgatgctca gtgagattat ccattcttgt ttttgtagcc
    39481 attacaataa aacggatgtg gaagtccagc aggaacttgg cattggaagg acttcgtttt
    39541 ataaaatgaa gaaacaggca ttgcggtatc ttgggttcta cttttacgag atcgtggtac
    39601 cgcaggcaaa aaacaaaaga ttcaaaccat ccttgggtgt ggaggaagag taggtgattg
    39661 ggatgaaata cgaaaattca atggtaaaga ttgcagatga tattatccgg gatcagatag
    39721 cagacaggaa tgttcagaac aaaaagcaga aatggcatga tgagtatgct accttgaaat
    39781 tttttcggta catatgcaga aatgttggaa accttcagga aggagaaatc cagcgtttgg
    39841 tatggaaact gaaacagtct gataagaaag cagtcgaaaa acatttaaaa ggctatgcgt
    39901 gggaatttga ttatgagaaa atgttttcta tattgacgca gaatcctgtt tgtcagaaag
    39961 tatgtcaaaa aaataaatat acaagctgga tgcatctgat cagccgatac tgtacagaag
    40021 attgttagga aataagatac cttcttgcat ctatcaatga attattttat ggaataaatc
    40081 ctgtattagt tctatagaac gataacttgt tttgcagctt ctgtatatcg gaacaggcgg
    40141 tagttatact aactttagac cgaaaaatag ttctaaagga ggtgctgcga tggatctgaa
    40201 agctgtagga cagagaatta agatggcaag ggaagcaaaa ggtctgacac aggaagattt
    40261 ggctgccatg gtggaactga gtccgacaca tgtaagtgtg attgagcggg gattgaaagc
    40321 cgcaaaactg gatacgtttg ttgcgatagc caacgctctg gaagtttctg cagattcact
    40381 tctgatagat gttgtggcac attctgtaac tggtgtgacg aatgaattat cagaaatgat
    40441 cgggaaactt ccaaaagaag agcagaagaa aatcatcaaa gcggtcaggg cattaacaga
    40501 atagttttta tgaggagggc ggaagccctt ctttttttgc ggtttgtgtc acaatttgtc
    40561 aaacgaatgg ggattctgtt ttgtttttat ctgtgatata gtagttctaa agaactatta
    40621 ctaattcaaa aagaggagat ataaaatgca cagaaaaact atttttgaga aagttgctga
    40681 aaaattccat accactccgg aagaggtata tgcggaaatc cagagagcga ttgatgcagg
    40741 atatgataac ccggatccag aggtacgggc agaatggcgt aaggttaaaa taaaagggaa
    40801 ccgaccaacg ccggaggaag taattaacta tgcagtaagt actttaacag cagaacagag
    40861 gtgatcatcg aagtgaagag gaaaaagcat acgttattat gtctgttatt ggcagcagcc
    40921 tttgtttcag gctgtgcgca gaaacataaa gagggagagc cggatgtcat tagcagtatg
    40981 aaaatgaatc aggatgaaat acttactgtt gttgcaaaca ggaaccagat tgaagataaa
    41041 gaggattttg caaaattcct tgtcaaaaaa tgcaaggata attcttttca gtctgttaaa
    41101 ttctctacag attatgggta tgccaccagc ctgaatctta gagtatatct ctgggaagat
    41161 gagatagaag gacaggagcc ggtaatgatg gttgaatata agcctgttga atggggaatg
    41221 gactatgata ttgtccatga tccggaaaag ttccaaatgt atgtggatgg agagctgatg
    41281 gaaaatccat agattttcag ataaaaatgg atgagctgtt ggagaaaaag agtaagtgaa
    41341 catttccctt gaaaatgtgt acaatccaat gagaataatg aacttttaag ccccgtaaac
    41401 ggacactttc tgaactttgc tctgatacaa tggttatgct gatgaaagaa ggcatagaaa
    41461 actgaattaa atttgagaga cggaagcctc agtagttaaa aaagactact ggggcttttt
    41521 ttcgtgcctg attttttcag ccaatacctg caggttttat ctggcagtag ttggtggagc
    41581 aggcatgaac cagatcagag gaccgccttc tgaatttgaa actaacaaac aaatttcaaa
    41641 ttcaggagga cggatatgta tattgaacat ccatataaat acgacgggaa atactacgca
    41701 aatgtagatg gaaagatgat tgaaatcaca aaggaagtgg cttatgccat gaataatttt
    41761 taccgaagca gccagccaag gaagatcgaa attaagaatg aaaaaggtga ggttgttgaa
    41821 cggaaactgc gggaaattcc ttacagcgag acgaatggac aggattatga attctctatc
    41881 gaggattttc cggactatag ctgtgatgtg gaagacagcg tgatcagcag tgcggagaga
    41941 cgagatatcc ataaggtaat taatcagctg gatgcagaag aacggatgat tatttatggc
    42001 atttattttg agaataaaac gcaggtacag ctggcaagga ttatgggagt gtcccggcag
    42061 gttctggcgt acaagctgaa tacaatttta aacaagatgc ggagaatgta tcaggaaaat
    42121 attttttgaa aaatctgcag attttttttg catccgggca agtcagttga atttagtaat
    42181 tagagagagt tttaaggact cctcaaaagt acattggaaa ctgaataccc agtaataact
    42241 gacgtgacat cttatgcagg aagcacaagg aagttgccgc caagactctg atgaatatcg
    42301 gacgagcgaa taagcactga ccgaaaatca actggcaggt tgatgatgcg gcgatctgta
    42361 tagggtgcga tacacttgcg gactgtgaaa agtctgtaac cggcaaacct atgaactgtc
    42421 ggagcctgcg tgcgggagca tttgggttgt gatctggcga atgcagtcag ataggttatt
    42481 attccctgcc tgcgtcagca ggataaacga ttcggggtat cgaggataaa tagaatcgag
    42541 cgagcactgt tttataatcg aaaattggct atagaggtta tgcggcagag cgttcatttt
    42601 gaatgtctct gccgtattcc tgtggagcta ataatggatg ctttacgatt aaatttcagg
    42661 atgggaggaa cgaataaatg aaaattgaaa gaggcgatat ccttatggtt aatttgggac
    42721 aggttccggg tacttccctt cagagtggaa tccgtccggt agtggttgtc agcaataata
    42781 aagcgaatac atacagtccg gtggtaacgg tggtgccgtt tacttcaagg gtgtacaaaa
    42841 aacgttatct tccgacccat gtgtttatta accgttatga aatggttggc ttgaaacggc
    42901 atgggctggt actggcggaa cagatcacaa gtattgatat tcagagtatc atccaaaaat
    42961 gtggtcatgt cagctctgat gcaatgcgga ggattaccag agcggtagag attcagacag
    43021 gagtttatga ggagggggat tatgacagca gaagaatata gaaagtatct ggaacaggat
    43081 ttttgtgatg taaatattga tgaaatgaca gatttactga caataaaagc agacaggaat
    43141 aaaagcctga aggaacggcg ggaatcatat ctgaataagg taggaaatcc gtatcttgtc
    43201 cggatcggga atatgaaggt caaagtaagg tttgccaata acggaatatc tttggagcag
    43261 gcatttgaaa atatgcttct gagtgtctga aaaagtactg gaaagtttgg ggtggctgtg
    43321 ctaaaatgtc tgtaaggaca aattatgcag ccccctttta ttacatgggt tttttgacgt
    43381 aataagagga ggtaagatat gtatcagaat ttcaataaaa tctatcgtgc cgccatctat
    43441 gtcagattat ccaaagaaga tggcgatctt tccggttctg caaaaatgga aagtaacagc
    43501 atttctaacc agaaggctct gattctggat ttcctgaaag acaaaaaaga tatagaagtt
    43561 gtttccgtcc gggttgacga tggctactca ggctctaatt tcgagcgccc tgcattccag
    43621 gctatgctgg aagatatcag gcgtgggatt gttgattgcg tagtggtgaa agatttatct
    43681 cggtttgggc gggaatacat tgattccggg aagtacattg aacgtttatt cccggctctt
    43741 ggtgtgcgct ttattgccat aaatgacaat tatgacagcc ttcagggaaa gaatcaggcc
    43801 gatgaaatta ttatcccatt caaaaactta atcaacgatg cttattgccg tgacatttcc
    43861 attaagatca gaagtaacct tgaaattaag aggaaaaagg gagaatgtgt gacacctttt
    43921 gtggcattcg ggtatcagaa agttaaggca gacaagcata agctggagat tgatccggtt
    43981 gcaggcagtg tagtacagga catctttaag atgaaactgc agggaatgag ccaggatgcg
    44041 attgccaacc gcctgaatga actgggtgtg ctttcaccat ttgaatataa gattagcagc
    44101 gggagtcatt atgaaaccgg gttccgacag aaagagcagg ctctttggag ttctgttgcg
    44161 gtacgcagaa tactggaaaa tgaggtttac attggaaacc ttgtgcaggg gaaacgtacg
    44221 acaccgaacc ataaagtgaa gcagtcctac gtaaagccgg aagatgattg gatccgtatt
    44281 gaaaagaacc atgagccgct ggtaagtgaa agggattttg agatcgtcca gcggcttttg
    44341 gggatggata cccgtacttc tcctgaccag aagcaggtgt atctgttgtc cggcattgct
    44401 gtatgtgcgg attgcggggc accgatgacg agaaaggtct caacagttgg tggaaagaaa
    44461 tatgcctatt atttatgttc cacaaataaa gaaacgaaac gctgctccag tcacagaatc
    44521 ccggaaaaag atctggaaaa cgtggtattg gtaatgctga aacagcatat ccataacatc
    44581 ctgcatttga aaagggtgtt ggagtttatc gggactgtac catttcagga aatcaatgtg
    44641 aaaaaactcc aggacaggct ggaaaagaaa aaaatggaga cagaacgctg taaggaactc
    44701 cgcatgatgc tttattccga tatgaaagag ggcatcgtat caaaagaaga ttatgtagaa
    44761 cttcatgcag catatggaaa aaggcttagg aatgcagaag agagtatccg ggcaatccag
    44821 aaagaaatgg ataacatgtt ggaaaaagca gatgcttcta acacatggct ggattatttt
    44881 gtgaaatatc aggatattga agtgctgacc aggacggtaa ttgtggaatt gattcgggaa
    44941 atcagagtcc atgacaaaaa gaatattgag atcgtctttg actttgatga ctgttatcag
    45001 gcattgctga cacagcttcc ggctatggga gtggaggttg caacagatcc ggataacaat
    45061 ctgcaggtca agataaagga ggttgtataa aatggcacga aaaagcagga aaagcattcc
    45121 tgaaacggtc agcagtgcag ccgttcagga agagatcaaa agaccgttcc gggcagggtt
    45181 atatgcaagg atttctatgg aaacagagga aacgatagag agggggacga tagaaaccca
    45241 ggtggaactg atgaaaaact atgtggctga tacagaggat atttcggttg cagaagttta
    45301 taaggattct gattattccg gtacaaattt tgaccgtcct ggatttacgc agatgatgga
    45361 agatatcaag catgggaaaa tcaactgcgt gattgtaaag gatttgtcca ggcttggcag
    45421 gaattatgta gaaacaagca attatattga gcgtgtattc ccgttctttc atgtacggtt
    45481 cctggcagtg acggatgatt ttgattcttt ccgtgaggga gtagatctga ctgttccctt
    45541 aaagaatatt atcaatgagt tctattccaa agaccttgca aaaaagagca gcagtgcaaa
    45601 aaaagcattg tggagagaag ggaaatttac cggtgcctgg gaaccctatg gatataggaa
    45661 atcagaacag gacaggcacc agctggtagt tgacgaggaa gctgccggac atttacgggc
    45721 gattttttct atgtatatgg atggatgcag ttacagtgat attgcaaaaa aactcaacgc
    45781 tgatggcgtc ttgtccccaa ctttgcagag ggaatattat agatccgggg aaaagccatc
    45841 cccagagtcc aaaccgtgga ataattatga agtaaaacgt gtgcttcagg atgttcattg
    45901 taccggggat tccgtatatg gaaaatatca gcagagcgtt ttccagggaa ataagcagag
    45961 aaacagaccg gagagtgagt ggatctatgc agagaatacc cacgaaggga ttatagataa
    46021 agaactgttc cgacaggtac aggacaaaat ccgggaattt acggaggaat ataaaaagcg
    46081 acatcagctg aataatggag ccatccggag ccagaatttt tatacaggca agatcaggtg
    46141 tggaggatgc ggcaaccgca tgatcctgtc cagggaaaaa tccgggacat tttattatct
    46201 ctgcggtgcc aatgcaaacc ataaatcagg aggaaaccag tgcaaggggc acagggtcaa
    46261 aaaagaatac gtggatgaag atgtccttcg cttgatccag tcacatatga aaaccgtatt
    46321 ggatacagaa aaaatgatcc gggaaatgaa ctccgcttcc agaaaccaga cgcaatattt
    46381 gctattggac aaggaagtag ggaagcttcg gcgggaactg agccggatca gtaagcgtaa
    46441 atctgattta tatgaggatt attcggaacg cctgattaca gaagaagaat acatgcagtt
    46501 ttcccgtatc tattccaatg aaatagaaaa catcaaaagc cgtctggatg cagtattgac
    46561 ggcgcaggta cggtattcca aagattatca tatcgaagaa ggatggggga aagtgataca
    46621 tacttatatg tctaagcgga agctgacaaa agaaatggtg gaagcctttg tggattccat
    46681 tattatccat ggtaagtatg attatgagat caaactggta tatgatgacc agtttgctga
    46741 attgcaaaag ataatgaaag agaaggaggt acagtcaaga tgacagaaaa taggaaaaca
    46801 gctgtctata tccgtttatc tatggaagat gagaatgtgg atggcagaac caaactggaa
    46861 agtgacagtg tgacttctca gaggatcctg ttgaaatcgt ttgtgatcga tcagcttggt
    46921 gtggatgagt cggatatcct tgaatatgtg gatgacggtg tcagcggcac ccatttcaaa
    46981 cgcaatggtt ttcaacagtt gcaggaggat atgaaaagcg gacagatcgg ctgtgtagtt
    47041 gtgaaagatt tctccaggtt tggcagggac tatctggaag tgggatttta tattgagtat
    47101 atttttccgc ttcttcagat cagatttatt tccattaatg acagttatga cagtgcagcc
    47161 agctctggaa tgaccggcgg tatgaatgtt gctttgaaga atctggttta taacatgtat
    47221 agcctggatt tgtcgaaaaa aatctcatcc gcaatgcaaa ccagaatgaa aaacggaaca
    47281 aggcttccgg taaatgccag atatggttat agaaagggca aagatggaag gttggaaatt
    47341 gatccggatt cggctaaagt ggtgaagatg attttccaga tggctgcaga aggtatgagc
    47401 tttgcagaga tcacaaggga actgaacaaa caggaaattg ccacctgtga tgagcagaaa
    47461 atgtcaagag gagagcaggt tcagttccga cggtttgata ccatcatgaa aaaacgctgg
    47521 aatccaacca cagtatctgc aatcatacgg gatgagattt atattggaac ccggatatgg
    47581 ggtaaaacac gctgcagtat gcacaccggt cataaggcgg ttattaatga cgagtctgac
    47641 tggatcaggc tggaaaacca ccatgatccg attgttgaca gggaactgtt tgaaaaagcg
    47701 aacagactgc atccgaaaaa atccagaggt gttgcagaaa caagaaccaa ttatacactg
    47761 gcaagacgca agaaacagcc agcactgatg ctgtgtgcac actgtggtca ttgtctggta
    47821 agagaaacag aacatctgtt gaaatgttca gatggacgta ccagcggtga ccatgtctgc
    47881 aaaagcctgg tggtgagacg tgagccactg gaaaagaata tcatggaact tgtccatcag
    47941 tttgcatttt ccatgctgga aaaccggaag attgttgaat caaggaacca gagcaaaggt
    48001 atggagacga atgttgcaga attgttgaaa cagagccgcc agttgtcttc tgaaaaaatg
    48061 aaactttatg atgagtacaa agatgaccgt attgaccggg aattgtacaa gcagaaagcg
    48121 ggacagatag gcagacagct ggaagaaatc agacgaaaga tagcagagtc tgaacgtgat
    48181 gcaaagattc ttgagcagaa caatactgcg aaggaaatga aactggaaga atttctgagc
    48241 atggagaaat tcgatacaga gaagttacgg gaaatcatca aggttatccg ggtgcatagc
    48301 caggaggaaa tcgaaattga atggaatttt gatgatgtat ttttagggca gagataaaat
    48361 gttctggaca agagcgattt tgtggaagat aataaaagtg ctggggtacc tgattggaat
    48421 ggtcaggtac tttccggcaa gaaaaaagaa ttattttttt tgtcccatac ttgacacgtc
    48481 cacatacctt taggcatacg ttctgtacca atatggcgaa caaaggaatg agtcctaata
    48541 tattacaata tataatgggg cataaaaaca ttactatgac gcttggctat tatgcacatg
    48601 gttcatttag ttctgcaaga gctgaaatgg aacggttatc tgcctagtgg tatgactaga
    48661 gtttactact tatttactac ttttgatggc attcttatac ggttaaatgc caacttatgc
    48721 aaagtatctt ccaaaaagaa aatgccgata ctccttgtag atacaggata tatcgacatt
    48781 taccaactta tgaaaagata atcaaattta atataagttt ttatattaaa aaaatgatta
    48841 ctttaaagaa atcatttttt attataatca ctgagacatc aaatattcta aataaaattt
    48901 ttacttatct ggaattgtat attttttcta taatattaac tacagcgtac attgcccagg
    48961 cacagatagc caatacaaat actcccatca ttactaaatc taatttaaac acttgagaac
    49021 catatactat caaatagcct attccatatc ttgaaactaa aaattctcca actattacac
    49081 ctacccatgc cataccaata ttaattttag ttaaatttat taaatttcct gtgtttgcag
    49141 gtaatatgag tttaaataat atttgagatt tactagctcc aaaactcttt aacatcttga
    49201 ttttttcttc gtctatattc ataaaataat tataagctga aagtatagta acaacaaccg
    49261 aaatagttac agctgttacg acgattcctt ctattccagc acctacccaa actataatta
    49321 taggagctaa agcagtctta ggaagagcat ttaaaactac caaaaaaggg tctaatattt
    49381 ttgataattt ttctgaccac caaagagcaa ttgctaccaa aatacctaat acagtaccta
    49441 taacaagacc aagaacagtt tcatatacag atattccaat atgtttaaat aattgaccac
    49501 tagatgcata ttgaataaat aaattgtaaa tatcacttgg tttgctaaat agaaatgtat
    49561 ttataacatt taagtcagct aaaagttccc agattacaat aaaaccaatt aaaattaata
    49621 gctggtagaa taatacattt cttttttctc tttttacacc tttaacatag tttatatatc
    49681 cttcagatct tttattaagc ctcatgtgta tctagctcct tccataatat gtcgaaatac
    49741 ttttgaaaat caggaacttt acgtgtttta agaggcgttt ttgttccatc catgttaagt
    49801 tcaatatcgt aaatattttt tatggtagct ggtcttttag atagtattgc aaccttatct
    49861 gatatgctta ttgcttctac tatagctaaa aaagtgcaac taattgctta aagaaacaga
    49921 attatccatt tcagcaccca tataaataat attaagattt cctaaattgc tatcccaaac
    49981 tatactatta ataatagtag ataataacaa tctcttatca tctaaactgg cattatcaac
    50041 ttcatcatta aatctcttca aattactaac aataatatca agattaatac tatcactact
    50101 aatattggca ttactagact ccaaagtatt aagcttatct tttaaaatat taatctcact
    50161 atttaagttc tcaatttgag aaactatata atcagaagca atgctatcag tattttttgc
    50221 aagctctata actaaatttt tgataagttt ttccttatct aaaatttgat ttttaagtaa
    50281 attagtctcg gattttaaaa cattaaaaat attaccagtc ttaatgttat tattattgaa
    50341 tgtacttatg atagattcct ctttacagtt cttgatttta tctataatta aactttcaac
    50401 taatggacca ttaaggtttt tgcagttaca attatcagcg ccaagcgttt tcttagtgcc
    50461 acaaatataa taatacttta aatctttatc agtttttcta cctttatagg taattctcat
    50521 attagaacca cacttaccac attttataaa accagataaa agagctgttt ttccagttgc
    50581 tatccttggg gttttatcac gatttttatc tagttgattt tgtacttcaa gccatatttc
    50641 aggttctatg actccatggt gttttgcaat tgctgctatt gagttagttg tatttttagc
    50701 ataagtaagg actccacatt ttttatctgg agtacctaca atatccatac cattattttt
    50761 aaggtattct aaaatttcat cattagcttt tacatatgct ggatttctaa gtattctaga
    50821 taaagaacta gggtcaaatt taccaccacg aggacctctt attccattat tatagatata
    50881 tttatataac ttagataagg acctaagttc taaatattta ttgtatatta actttacaac
    50941 ctccatttgc tcatcattta cttgaagctt atacatactt ctttctttta ggttttcatc
    51001 taagaatgtg attttttcgc tgttaaatcc atgaggtgta ttgcctccaa gccatctacc
    51061 actacgagct aattcataca tattatcttt tatacgttct gctattgttt ctctttctag
    51121 ttgagcaaat acacttgata taaacatcat agctcttccc attggagttg aggtatcaaa
    51181 ttgttctttg atagatataa atgatatgtt tagttcattt aatttttcta ttaaggtaga
    51241 gaagtcagat acatttctcg atattctatc taatctatag caaactaggt aattaaattt
    51301 cttatccttg gcatcctgca tcattttctt aaattgtggt ctatctatat tactaccact
    51361 aaacccctca tcttcatata tcaaaaaatc ttttatacca atagactttg cataatcaat
    51421 acataattgt atttgatttt ctatagagtc gccttttcca gtaaatcttg attttcttga
    51481 ataaattgca gctttcaaaa ttaaaacctc ctataagtta ggacatatat ttagaattat
    51541 ttatatacaa tcttttaagt aaacttatta gaatgaattt attaattagg taaatttata
    51601 taattctact ttttataata tatgactatt tattttattt ctttactatt caagttctaa
    51661 atcaataata aattttggta tttaattgta tcaggacaaa tctctaattt catagattat
    51721 taatataaaa tcataagtta gtatgaaaaa attaaaattt aaatatttta aaagataatt
    51781 ttttggaact aatagctata acaaaaattt atagggggat tgtatatgga aatcaatgtt
    51841 atagaaattt tccctaaaga taaagctaaa cttaacgaaa tagaaatgaa taaagctagt
    51901 tggtttgtaa atataataag taaaaaatat cctaaagaag ctttaaatga agcatttagt
    51961 actttagaaa aagaattaaa tataagtaaa gctaatacat aagctttgat tattgatttt
    52021 atatattatt gaatttgtac actatgactt gacattatat taatcaaata gtatattttt
    52081 aaatatagca caatgaagtg ttaaaagagc aatggagctc catagataaa gtctatggag
    52141 cttttttgcg tatttaactt aaggaggaca gaaatttgaa taactttgag attaaaacta
    52201 gaataaaatt tggagaaggt tcactgaaag ctttacaaga actaaaaaac aaaaatgtat
    52261 tgataataac agacccattt atggtgaaat caaaaacaat agataaaata acatctaatt
    52321 tggtaaactc aacatatcaa gtttttgaag aaatagtacc agacccacca atagaagtag
    52381 tagtatcagg gatagaagca tttaaatcta taaatccaga tgtaataata gcattaggtg
    52441 gtggctctgc aatagatgca gcaaaatcta taatggactt ttctaaaaaa atattaaaaa
    52501 ttaacgaagt agagtttata gcaataccaa caacaagtgg aacaggttca gaagtaacat
    52561 catttgctgt aataacagat agtcaaaaaa aatgtaagta tccattagta agtgatgatt
    52621 tacttccaga catggcaata ctagacccag agcttgtaaa aactgtaccg aactttataa
    52681 cagcagatac aggaatggat gtattgacac atgctataga ggcttatgta tctacaaatt
    52741 ctaatgattt ttcagatgca ctagctgaaa aagccataaa attagtattt aaatacttaa
    52801 taaaagcata taaagatgga aatgatatag aagctcgaga aaaaatgcac aatgcatctt
    52861 gtttagcagg tatggcattt aaccaagcat cacttggaat aaatcattct attgcacatg
    52921 tattaggtgg aaaattccat ataccacatg gaagaacaaa ctctatatta cttcctcatg
    52981 taatagaata taattcatca atagtaggat atactaacac aacttactct gatacagcta
    53041 aaaaatatgc acaaatagca aaattagtag gacttgggaa tgctaatata agaatatctg
    53101 ttagaaattt ggtaaatgaa ataaagaaac tacaaaaaga aatgaatatg ccaactaaat
    53161 tgacacagtg caaattaagt ttagaagata taactaatga agaaagagaa atagcaaagc
    53221 ttgctataaa agatacttgt acattaacta atcctaaggt accaactgaa gatgatataa
    53281 taaacatatt aaataatatt aaataactac attttattac atgtaaacat aatcttatac
    53341 aaataaggaa aatgttttta aaaatataaa ttatatattg acaaatataa aacataaaac
    53401 tataatgaaa gtatcacaaa ggcgtgatac tttattagaa agcaatggag cttcttagga
    53461 atattaatat tattcttatg gagctccttt tattttaagc aattatcttt ttagtaaact
    53521 atatttaaag aaagtaggga ataaatttga ctgaagaatc taagcaaaga gttattcaag
    53581 aatatgttcc tggaaaacag gttacattag cacatatcat agctaaccct aatgaagata
    53641 tatataagaa gttaggatta gtacttgata aaaaagatgc aataggaata cttacaataa
    53701 cgccaagtga agcgtcaata atagcagcag atgttgctac aaaggcttca aatgtatctt
    53761 taggttttat agatagattt agtggttcag tagtaatatc aggtgatgta agttctgtag
    53821 aatcagcgtt aaatgatgtt ttggaagtct taggaaatat gttaaacttc tcatctacaa
    53881 aaataacaag gacataataa tacaatgaag aatataatat ttatgggaaa gacagggagt
    53941 ggtaaaacta ctttatgtca aaaattagac cagttagaat taaactataa aaaaactcaa
    54001 tcagtggaac tttataataa tgcaatagac actcctggtg agtatatgga aaatagaaac
    54061 ctgtacaatg ccttaataac aacatcagca gatgctaaaa ttatagcaat agtgtatgat
    54121 gccacacaag aagaaaatta tatagcacca ggttttgcaa gtatgttttg caaagacgta
    54181 ataggaatta taactaaaat aaataaagct actgaaaatg aagtcaatat agcttatgaa
    54241 agactatcac tagcaggagc aagtcaaatc tttaaaatag acacagttga taatattgga
    54301 cttgaaaaat tatttaaata tctagaaaaa tctaaaaata tagatgaagt ttaaggggaa
    54361 aatatttttt tattcaaaaa tattattaaa gtatgataaa ataaaaaaat gtataaacta
    54421 ttttaagaag atttaatctt taagcgaggt aggaacatgg ggaaaaaaat actattggtt
    54481 gatgatgaac cactgttaag gatggataca aaagatatat tagaaagtca tggctatgaa
    54541 ataataggcg aagcaagtga tggatttgaa gctgttgaaa tgtgtaaaaa acacaaacct
    54601 gatttagtta taatggatat agagatgcca atacttgatg gtataaaagc aggaaaaatt
    54661 atatgtaaag aaaatctagc tggtggagta cttttattaa cttcatttga agataaagaa
    54721 tacgtagaaa aggctaaaag tataggtgct tatggatact tggtaaagac agcaagtgaa
    54781 aaatcactta ttccaactat agaaatgtgt ttaaataagg taaatgaatt tgaaaaaatg
    54841 aaaaaagatt tagaaaaagt aaattctaaa ttgaatgaaa gaaaattagt agaaagagca
    54901 aaaggtatac ttataagaga gtttaagatt tctgaggatg aagcatacac tagaataaga
    54961 aaattaagta tggataaaag aaccacaatg atggaaattg ccaaaatgat tataatagga
    55021 tacgatgact aatacgataa aaaaaatatc aactgcacaa acatacttaa ataataatga
    55081 aattgaaaaa attatagaag tatcaaaatc cttagattta atggcttctt tttatgaggc
    55141 tgatgttttt atagatatac taagtaaaat tgatgatgaa gcaattgttg tggcacatgg
    55201 tagacctaaa gaaaagtcaa tgtactgtga aaatgttata ggcaaaaagg ctttaattga
    55261 aaatgaacca ggagttataa agtgcttaaa aacaggagaa agagtaagag atataaaagc
    55321 tttgacacaa gaatataaac tggtcaagca aaatattcag ccaataacgc tagatgacaa
    55381 agttttagca gtattaatag ttgaaaaaga tataagtagt gaagtcaaga atgagtttaa
    55441 cgctagtgaa gacgaagaaa ataaaaattt acatcagttt ataaaactta taggaaataa
    55501 tgacttttta gttgataatt taaattcagc tatactaatt tttgataaaa atggaaattt
    55561 aaaaattaaa aatcgtattg caactgagat atataaaaat cttgggtttg gatatgatat
    55621 acaagatatg cattataatg acttagatat agaaaccaat acatttgaag atatattaat
    55681 ggatgaaaat tatgatgaga caaatgaagt ttcaatagat aatatgtttt ttaaaataaa
    55741 aaccatatac atcaaagatg atgaatttaa ggtttgcaaa atagtacaag atataagtga
    55801 tttaaagcga aaagaagaag aattagtttt aaaaacagta gctataagag aagctcatca
    55861 tagagtaaaa aataatcttc atacagtaat atctataata aaaaaacaaa gtagattatc
    55921 tcaaaatgat gaagttaagc agtgcttgga taatataata aatagggtat ttgcaatact
    55981 ttcgactcat tatttactat ctaaagaagt tgataataat atatctatac gagaaggtat
    56041 caatttatta gtgtcaaata ttcaaggtag ctatttattt agtaaagata tagatatacg
    56101 tataactggt gaagatttta aaattagtgg agaaaaagca acagcaatac ttttagttat
    56161 aaatgaaata ctacaaaatt gttatgacca tgccttttta gatagagaac atggtactat
    56221 acaaatatta ataaataaag ataataacta tagaaatatt gctattatag atgatggagt
    56281 tggatttgat agcgataata taaataaaaa tagtttaggg acatatataa tagatagtta
    56341 tataacacaa atgttaaaag gaaatataga gagaaaaagt aataagaatg gtacagaaat
    56401 attaattact atacctacac aaattaatat ttaaataata actcatctac aaagtagtag
    56461 ttttaattga gcaaagaggc ttaaggttat taatagatta agttaattga atgtatttat
    56521 aaaaattata agtatatatt caatttaata gatatttatt ataactttaa gcctctttgc
    56581 ttgtttaaga catacttaaa ttttaggagg tgagaaaatg agagaagagt tattaagtgt
    56641 tggtattgac attggaacaa gtactactca gttaattttt tctaaattaa tagtagaaaa
    56701 tactgaatca aatttttcag tacctagaat aagtatagta gacaaagaaa ttatttataa
    56761 aagtaaagtt tatttcactc ctcttatttc aaataatgaa ataaatggtc aacaaataaa
    56821 agacatagtt gaaaatgaat ataaaaaagc aaatatatct aaagtggata tacatacagg
    56881 agcagtaata ataactggtg aaacagctag aaaagaaaat gcaaatgatg tgcttcatac
    56941 tttgagtgga tttgctgggg actttgttgt tgcaacagca ggacctgatt tagaaagtat
    57001 aatatcagga aaaggggctg gagctcatat ttattcaaaa gaacattcaa ctacaattgt
    57061 aaatatagac ataggtgggg gaactagtaa tatagcttca tttaaaaggg gtgaagtaat
    57121 tgatactggg tgtttggata taggtggaag gcttataaag atagataaaa taagtaaaaa
    57181 aataacttat atatcaccta aaatagataa aatcataaaa gataataatt taaatcttca
    57241 agtaggtaca atagctacca tagaaaatac aaaaccaata gtagatataa tggttgacct
    57301 attaatggaa agcataggat taaaaaaaca gacaccttta tttgatttta taataaccaa
    57361 taaatcaata agtgtagatg aaaatattaa aaatgtttca ttctctggtg gagtagctga
    57421 ttatatttac tatgatgggg aaataaaaga ttattttgaa tatggtgact tgggaatttt
    57481 acttggacaa gcaataaaaa attgtaaata ccttaaaaaa gtaaatgtag ttaaatctat
    57541 ggaaacaata agagctacag tggttggagc tggttctcat actactgaag taagtggaag
    57601 tacaataact tacactagcg aaaagtttcc acttaaaaac ttgccagttt taaaattatc
    57661 aattgatgaa gaaacaggta cttcaaaaca aatcagtgaa gctataaaaa ataaacttaa
    57721 ttggtttaaa ctagaaaatg atttacaaaa agttgctata gccatgatag gaaagaaaaa
    57781 tccaaccttt ttagatatac aagagtatgc caaaggattt gtagatggaa tgcaacaaat
    57841 tatagaaaat gatttacctt ttatagtaat tgttgaaaat gatatggcaa aagtattagg
    57901 tcaagctata tatgcattat taaattataa aaaagagatt gtttgtatag acagtgtcaa
    57961 ggttgaaaat ggagactata tcgacattgg aaaacctata gttgaaggta aagttttacc
    58021 tgtggtaata aaaacattag tttttaatta atagaaggag gtaagtaaat gattttaaag
    58081 acaaaattat ttggacgtac ttatcagttt aaaggcttat atgatgtaat ggctaaagct
    58141 aatgaagaaa aatcaggaga taaattagca gggcttgcag cagaatcagc tgaagaaaga
    58201 atagcagcaa aagttgtttt atcacatata aaattggagg atataagaaa taatcctgca
    58261 gtagcatatg aagaagatga agtaacaaga ataatacaag atgctgtaaa tgaaaaagtt
    58321 tatgaagaaa taaaaaattg gacagtatcc gaacttagag aatggatatt agattcaaat
    58381 actacaagtc ttgatataag aagaatatca agaggattaa cttctgaaat gatagcagca
    58441 gttgcaaaat taatgtcaaa tatggactta gtttatgcag ccaaaaagat aagggttact
    58501 gcccactgta atacaactat aggagaacaa ggaacattat cagcaagact tcaacctaat
    58561 catccaacag atgacccaga tggaatactt gcatcacttc ttgaaggttt aacttttggt
    58621 ataggagatg cagtacttgg attaaatcca gttgatgact ctgttgaaag tgttactaaa
    58681 gtattaaaaa gatttgaaga agtaaaacaa aaatatcaaa taccaactca aacatgtgta
    58741 ttggcacacg ttactacaca aatggaagca ataagaaatg gtgctcctgc agatttgata
    58801 ttccaatcta tagcaggttc tgaaaaagga aatgaagcat ttggatttaa tggcgatact
    58861 atagaagaag ctagacagtt agctttgaag tatggtacag ctacaggacc taatgttatg
    58921 tattttgaaa ctggacaagg ttcagaatta tcttcagaag cacatcatgg aatagaccaa
    58981 gttactatgg aagctagatg ttatggattt gctaaaaaat acgaaccatt cttagtgaac
    59041 acagttgttg ggtttatagg acctgagtac ttatatgatg ctagagaagt tgtaagagca
    59101 ggacttgaag accactttat gggtaaacta catggcttac caatgggtgt tgatgtttgt
    59161 tacactaacc atatgaaggc tgaccaaaat gatatggaaa acttagctat actattaaca
    59221 acagcaggat gtacgtattt tatgggaata cctcatggag atgatgttat gcttaactat
    59281 caaacaacag gataccatga aacagcatca cttagagaaa tgtttgggct aacagcaata
    59341 aaagaatttg atgcttggat ggaaaagatg ggattctcta aagatggtaa gttaacagag
    59401 ttggcgggag acgcgtctgt attattagga taggaggtat ttaatatgaa tgagaaggat
    59461 ttaaaagcat tagtagaaca attagttgga caaatggttg gagaattaga tactaatgtt
    59521 gtatctgaaa ctgttaaaaa agcaactgaa gttgtagtag acaacaatgc ttgtatagat
    59581 gatataacag aagttgatat aagaaagcaa ttactagtaa aaaatcctaa ggatgcagaa
    59641 gcttatttag atatgaaagc aaaaacacct gcaagattag gtataggaag aaccggcact
    59701 agatataaaa cagaaacagt tttaagattt agagcagacc atgctgctgc acaagatgct
    59761 gtattctctt atgtagatga agaatttata aaagaaaata atatgtttgc agtagaaact
    59821 ttatgtaaag ataaagatga atacttaaca agaccagatt tgggaagaaa attttctcca
    59881 gaaactataa ataatataaa atctaaattt ggtacaaatc aaaaggtttt aatattagtt
    59941 ggagatggac ttagttcagc tgcgatagag gcaaatttaa aagactgtgt gccagctata
    60001 aaacaaggtc taaaaatgta tggtatagat tcaagtgaaa ttttatttgt taaacattgt
    60061 agggttggtg ctatggacca cttaggtgaa gaattaggct gtgaagttat atgcatgttg
    60121 gttggagaaa gaccaggact agttactgct gaatcaatgt cagcatatat agcttataag
    60181 ccatatatag gaatggcaga ggcaaaaaga acagttatat caaacattca caaaggtgga
    60241 acaactgcag ttgaagcagg tgctcatata gctgaactta taaaaactat gttagataaa
    60301 aaagcttcag gaatagacct taaataaagt cgagggagtg tagaatatga aaaacgatgt
    60361 aattcgtcct aatatactag gaattaaaat aatttcgaat ataagtccag aaatggcaca
    60421 aaaactagaa ctaaaatcac atcacaaaag tttaggttta ataactgcag attgtgatga
    60481 tgttacgtac acagctcttg atgaagcaac taaagcttca gaagttgatg ttgtatatgc
    60541 aaaatcaatg tatgcaggtg ctgcaaatgc ttcaacaaaa cttgctggtg aagtattagg
    60601 aataatagca ggaccaagcc cagcagaagt aagaagtggt ctaaatgcag tagttgattt
    60661 tctagaatat ggagcaactt ttataagtgc aaatgatgat gattcaatag catattatgc
    60721 tcactgcgta tcaagaacag gtacatacct ttcagaggta gcaggaataa gagaaggtga
    60781 agcattagct tacttagtag caccaccact tgaagcaatg tatgcactag atgcagcaat
    60841 gaaagcagca gatgttaaaa tgtgtgaatt atttgcacct ccaactgaaa caaactttgg
    60901 tggagcatta cttacaggtt ctcaatcggc ttgtaaagca gcatgtgatg catttgcaga
    60961 agcagtaaaa tcagttgcag acaatccaac aggattttaa ggatagttag atggatgcta
    61021 taggcttaat agaagtaata ggatatgttg ctgcaataga agcttctgat gcttgtttaa
    61081 aatctgcaaa tgttaatatt gtaagaattg ataaggttgg ggcaggtatt gttactttga
    61141 caatatgtgg ggatgttggt gctgtaaaat ctgctttaga agcaggtgaa atagcagctt
    61201 ccagagttgg tacattaaga acatcacata ttataccaag aatccatgat gaagtaacag
    61261 atgctttatt caaaactaaa gaacctaaag tctgtgaagt ttcagaagat aaagagaaaa
    61321 actttgaggt tacattggaa acaactgata atgtatcgaa aaatttatca gaaaaagaag
    61381 atgtaatttt agatgtcact gagaatagtg gaaatattga aaaattatat agtgatatag
    61441 ataaaatcaa caaagaaatt gaaacagttg atgatatttt aacagaagct aataagggaa
    61501 aaatagaaaa tactaacatt gataaaaaag tattggaaca ggttaaaata gaaaatttcg
    61561 attttgatag agatgaccta tcaaagaaca gcgtgaaaaa acttaaagct atggctaaga
    61621 aattagattc ttcaataact tataaagatt taaatgttct taaaaaagaa gaattaataa
    61681 acttagttaa aaagcttagc agaagggata gatagttatg acactcttag ataaagattt
    61741 agtatctata caagaagtca gaactcttgt aagaagatct aaagtggctc aagataaact
    61801 ttctaaaatg agtcaagagc aaatagataa aatagtaaaa gctattgcag atgcagcatt
    61861 taataatgct actaaattag ctaaaatggc aaatgaagaa actggatttg gaaaatggga
    61921 agataaagta attaaaaata cttttgcatc tatgggagtt tatgaaactt taaagaacac
    61981 aaaaactatt ggaataatta gtgaagataa agaagcaaat acaatagata tagctacacc
    62041 agttggagtc gtggcaggtc ttataccttc aacaaaccca acatcaacag taatatacaa
    62101 aactataata tctctaaaag caggaaatac tatagttttc tctccacatc caaatgcaaa
    62161 aaattgcata cttgaaacag ttaatataat aagtgatgca gctataaaag ctggagctcc
    62221 agaagattca atattatgta taactaatcc aagtatagtt ggaactaatg aactgatgaa
    62281 acataaagat acaaacttaa tactagcaac tggaggagaa gcaatggtta gagctgctta
    62341 ctcttcagga acaccagcta taggagttgg acctggaaat ggacctgcat ttatagataa
    62401 atcagcaaat gttaagttag caatcaaaag aataatagat tctaaaactt ttgataatgg
    62461 tgttatatgt gcatcagaac aatctatagt aatagaaaaa tctatggaag agactgtttt
    62521 aaaagaactt aaaaatcaag gtgcatatgt tttaaatgaa gaagaaagta aaaaattagc
    62581 aaaatttata ttgagagcta acggtactat gaatccacaa atagttggta agagtgttga
    62641 ggtaatagca aatttagcag acttaacaaa tgtgcctaaa aatacaaaag ttctagttgc
    62701 aagagaaaat aaggttggcc acaatgtagc ctattcaaga gaaaaactta caccaatact
    62761 agcgttctat gttgaagaaa atgtagaagc tattatgaac agatgtagag aaatattatt
    62821 aaatgaaggt gccggtcaca cattctccat gcatgcaaat gatgaagaat tggtaaaaag
    62881 atttgctctt aacatgccag tatcaagaat acttgtgaat actccttcag cacttggagg
    62941 aataggtgca tcaacaaatc ttgtaccagc actaacactt ggttgtggtg caataggtgg
    63001 aagttcaact tcaaacaata taggaccact tgatttaata aatgttaaaa gagtagctta
    63061 tggaatcaaa gaaatagaag aacttggaag agataaatct caagttgaaa aatcaatgtt
    63121 tgactcaatt gataaagaag aattaataaa tcttcttgtt caaaaactag tcaaagaact
    63181 aggataacta aaataaacaa tgaaacttat agctatagct ataaatttct aaaaatataa
    63241 actataaaat taaatttttg gaggataaga ttatggcaag tgcaaacgca ttaggaatga
    63301 tagaaactaa aggattagta ggagcaatag aagcagcaga tgcaatggtt aaagcagcaa
    63361 atgtacaatt agtaggaaaa gagcaagtag gtggaggatt agttactgta atggtaagag
    63421 gagatgttgg ggctgttaaa gctgctacag atgcaggagc tgcagctgct gagagagttg
    63481 gagaactaat atcagttcat gttataccaa gaccacactt tgaagtagat gctatattac
    63541 caaaagtatc agctgagtaa tataaaaata attttaaaat ttaaattttg attgaaaaag
    63601 aggctatctc aaaaatgagt cttactaata aactcaatgt attttgaggt agtctttttt
    63661 atacatctaa taggagatgt gataaaatgg gtgttttaac agaaaacgaa ataaagagaa
    63721 aaattggaaa aaacaaaaat aatataactg aattttatat agaaaaagga caaataataa
    63781 ctccttctgc aaaatcttat ttagctgaga gaagtattga acttaaatat gttgataaac
    63841 tttcagatgt aaataatgag cctaaagaag ttgtaaagga agtagttaaa gaaaaaacat
    63901 ataaatatac tactgtattt ggtgctaaat tggatgaaaa accagaacac atgactcaat
    63961 taaatggaaa tcttttagtt tttaaagacc ataaaagaat aatattgaga ggaaaaatag
    64021 attctcttga atcagaaata ctaaaggcac agatactttg tcagaaacta gatatgccaa
    64081 agctcgttaa ggaattgcaa gaagttttag actttgtaag aaatataatg agatgtgaag
    64141 ttttagaaga aaaactagag gactttaaac ttttaggatt aactcctcaa gaacttagag
    64201 aacaatctca ctatcctaaa aaatactttg gtataggaca tgagttccca agttatgaaa
    64261 tgggagaagt agtagtagct ataaatagta taagaagtaa tacacgagag gttgaacttg
    64321 cagcctatga agcatttaag ggtgagtatg gaaatgttca tagagaagat ttaataaagg
    64381 cacttaatag attatcgtca gtattttgga taatgatata taaagttaga actaataagt
    64441 ataagtagtt ggaggacaca atggagaatc tattaaatga aatagtggaa gaagtaataa
    64501 ctagagttaa aaaagaagca tttatagaag ttgaagcatc aggaagacac gttcacttaa
    64561 gtagagaaga tgtagataaa ttatttggta aaggatatac tcttacaaaa ctaaaagacc
    64621 tatctcaacc cggtcaatat gcttgtaagg aaagagtcac aataactggt cctaaaggaa
    64681 gtataaaaaa tgtagttgta cttggaccat gtagaaatga aactcaggta gaaatatctt
    64741 taacagatgg tttaactctt ggactaaaag ctcctataaa acagagtgga gacttagaag
    64801 ggactttaag tattaaaata tcaacacaac atggtgaagt tgaacttgat aagggattaa
    64861 tggttgctaa gagacatata cacatgactc ctaaagacgc tgaaaatttc aatgtatgtg
    64921 ataaagaaat tgttgaagcc aaagtgatgg gtcaaagacc tttaacattt gatgatgtag
    64981 taataagagt gagtgacagt tttaaaactt atatgcatat agattatgat gaagccaatg
    65041 catgtggtta ttcaaaaggg actgttgcta aaataataaa gaaagtataa atttaaccta
    65101 ctatataaat tacctctggg gaggatttaa tatgaattat gataatcttg tagatttaat
    65161 aatggaagaa atctataaaa aagtaaatag caatgaaata aaaatatcta ataaacctaa
    65221 agctgtgatt gtatttgaac aagacaccaa taaatttaac ttattaaaag atgaatttga
    65281 aatagtggaa tttgataaaa gtataaagga atgtgaaata gtgatagttt caagactttg
    65341 tatgagggga ttatcgaata tagcacttgg aaattcaaca agtgatgaag aaagatttat
    65401 actaaaaatg attatgagtg gcaaaaaagt gtatgtttta gatgaaggaa ttgaatacaa
    65461 aaaatataag gatactgcac caaaagcatt atataagaaa tttatatcat ttgaagatga
    65521 aatatgtaaa tttggtgtag aaattataaa agacttaaat gctataacta aaaataagtt
    65581 aaacataaaa agagaactag aaagtactat aggttctaaa aaagaagata caaaagcttt
    65641 agataaagat gttttaaatt taaccagtgt agaaagtgta aaaatagata atgaatttag
    65701 tttagattta agaaatagaa aacttatatc ggaagctgac ttaagaaaac caactataaa
    65761 tggagttaaa aacatactag ttaataaaaa aagtataata acaccattag ctgtagattt
    65821 tatgagaata caccatctca aactaaagaa agtataagga ggtaatttta tggatatagg
    65881 aaaagttgta ggtaatgttt gggccacaag aaaagatgaa aaattatgtg gccaaaaact
    65941 tttagttgta aaaattttaa aaactaaagg cacatacaag gaaggcttca tggttgcagc
    66001 cgataatgca ggagcaggaa atggagactt ggttcttata tccagaggtt cctcagctag
    66061 agagtcgatt gaaaaagctc atgttccagt agatgcaact atagttggag tagtcgattc
    66121 gtttgaggtg tttgatgaat aaaagtatag gagctataga atttaaaagt attgctaaag
    66181 gtatagaagt atccaatgaa atgataaaga aatcttcagt tgatgtattg tacttaaaaa
    66241 gtatttgtcc aggtaaattt ctaatagtag taggtggaga aacttcttat gtaaatgaat
    66301 gtgtagatta tggaataaaa cttggagaag gatatattgt agataacttt gtaataaatg
    66361 caatttcaca agaaatatta gatggattta aaaataagta tcaaaagtta gataatatag
    66421 tctctatagg tgttgttgaa agtggtaagg tatgtgctgg aataaaaatg cttgatagga
    66481 ctttaaaatc aggcgaatta gtattagtaa aacttcaatt atcttttgct ataggtggaa
    66541 aattagtata tatagtagca ggagatttaa gtagtttaga atatgcatta aaagaaagtg
    66601 aagatgtagt aagagaaaaa gaagtaatat ataagactgt aataccatca gtagacagtc
    66661 aaataataaa aagtctaata aaataatggg gggaattatg agtataaacg aaattataat
    66721 ctatgtaatg gtaatattca tggtgcttgg agctatagat aaatgtatag gtaacaaatt
    66781 tggtcttgga gagcaatttg aagaaggtat aatggcaatg ggttcacttg cagttgcaat
    66841 ggttggtgtt atatgtttag caccagttct tgctgatgta ttaagaccaa tcgtagtgcc
    66901 agtatttaat atacttggag ctgacccagc tatgtttgct ggaagtttat tagctaatga
    66961 tatgggtggt gctccacttg cacttgaact tgcaaaagac cctaatgctg ggttatttgg
    67021 tggattaata gtaggtgcta tgatgggacc tacaatagta tttataatac cagttgcact
    67081 tggaataatt gaaaaagaag accaaaaatt cttagcaaca ggaatacttg caggtataat
    67141 aacaatacct attggagcat tcgttggtgg attagttgca ggatttgaga taatgatggt
    67201 tcttagaaac ttagtaccaa taataatatt tgcagtagtt atagcacttg gattattgaa
    67261 atttgaaaat gctatgataa aagggttcac atactttgga aagggtgtag taatagttat
    67321 aactttagga tttgctgctg ctatagttga agctttaaca gggatagttg taatacctgg
    67381 aatgaagcca ataagtgaag gtatagaaat agttggagat atagcaatag ttttggcagg
    67441 agcattccca ctagtgtttg ttataacaaa ggtatttaat aaaccattaa tggctttagg
    67501 aaaagttctt ggaatgaatg atgtgtcagc agcagggctt gttgcaagtt tagctaactg
    67561 tataccaatg tttggtatga tgaaagatat ggacaataga ggaaagataa taaatgtagc
    67621 attctctgta tcagcggcat tcgtatttgg agaccactta ggatttacag caggatttaa
    67681 ttctaatatg ataacaccaa tgatagttgc taaattagtt ggcggtataa cagcagtatt
    67741 attggctatg gttatcgcaa ataagacact aaaaaaggag aatgtataag atggatatat
    67801 caaatataga taaaaattta attgaaacat tagtaagaca aataatagaa gaaaaaataa
    67861 gtggaactaa ggacacagta gattttgtta gaaataaaga tattagtgga attacttcta
    67921 taaagttacc aactgtaaaa gttagtgaat ctgatagatt agatacagga aatccaagtg
    67981 atgtagttta cacaaaggat ttatttacat tggaggaaag cccaagatta ggttgtggta
    68041 tgatggaaat gaaagaaaca acttttgatt ggactctaaa ctatgatgaa atagattatg
    68101 taatagatgg aactttagat ataataatag atggaagaaa ggtttctgct tcttcaggtg
    68161 agttaatatt tataccaaaa ggaagtaaga tacaattttc tgtacctgat tatgctagat
    68221 ttatatatgt aacatatcca gcagattggg catctcaaaa ttaacaagaa ccaaattaag
    68281 ttaataataa tcaaataaat agtttaaaat aaaaactctt attaaacaca catatttaaa
    68341 aaggctatga attttaattc atagccttta attatgaaca atgttatact ttagtagtat
    68401 tttttctata tttactggga gacatattat attttttgtt aaataatcta ataaaatgct
    68461 ctacatttgg ataaccaaca ttgttgctaa tatcagcaat aggaatattt gtattcatta
    68521 acaaactttc agctctttca agtctaattc tttgtaataa ttgagtaaaa ttacaacctg
    68581 caatttcttt aataatttta gaacaataag gtatagaaaa gtgaaattta ttagcaagtt
    68641 cttctaaggt tatatcaaca taattatctt ggatataagt aagaatattt gtgtgattta
    68701 aagtaccttt tttcgtcaca ttaggaactt ctatactatc ttcatagtct ctaagtaatt
    68761 ttgcaaaaaa caccattatt aaatgattaa gtatattatt ataatatcta tcttgttcat
    68821 tatattctga aagcatctct aaaatagaga tttctattga tttatcatta tttgtatgaa
    68881 aaagtatgta atcattctgt ttgtctttat aaatactatt taaaaagaag gatgaaagca
    68941 agttgttgtt tcttaaaaaa tcaaagaaag catcctcaaa agtacttcta cgtattaata
    69001 cattgataat aatactatca tcaaatactc ctatagaatg ttttactcca ggtgaaacta
    69061 tacaaatatc tccttctttc atatgtacat tatgatgatt aattacctga tagcacttac
    69121 ctgataagac ataaatcatt tcaaagaata tatgctcatg cacaaattga ggtgtgtagc
    69181 gattatgttt tataagtata acgttatcct tgctgttaca ctcaaaataa gtttcatctt
    69241 tcataagttg aggaatcttt tcattataaa tatatggaat aattagatta ttattaacta
    69301 tgtaatcctc atctaagtta tcaataaata gttttaggga ttctggattt tgttttgcaa
    69361 aataataatt tttataaaat aactcagatt cattataaat ataaagattt tgaaataatt
    69421 tatttaaact cataaaatct ccttcatctc taagattgtt taaatataaa ataaaaatat
    69481 cataaatatg aaaataaatc aattaaattg gttaaaaacg acaatagttc aagcattttc
    69541 taaaggatat aatgatgtta agtcattaga aataataaaa acaacaaaat aaggggggat
    69601 tataaatgac tactttaaaa gttgttgatg aaaagaatgt accaggaatt tggcgtcaaa
    69661 gaataggcta tgggtcatct gacctagctt gtaacctaat ttggcaaatg atatcgttat
    69721 atcttttata tttttacaca gatattatgg gattaagtgc tgtagcaata agttttatgt
    69781 ttgttgtaac aagggtaatt gatggaatta cagatttatt ggttggttat tgtatagata
    69841 aaacaaatac tcgttggggt aaatcaagac cgtatttcct atttggtgca gtaccatttg
    69901 cattattcgc agtactagca tttagcgttc cagatatatc attaagtgga aagttaattt
    69961 atgcttatgt tacatatatt ggattatctt taacttatac tatagtaaat attccaatgg
    70021 cttcaatatt accaagttta acagatgata ctaatgagag aacagcatta tcaacatcaa
    70081 gaaaattctt tggattttta ggttcaacaa tagtaagtta tagtgcttta actttagtgg
    70141 gaaagtttgg aggcactgat gaagctctag ggtttaaagt agttatgatg ctatttgcat
    70201 ttataggatg tgcaatattc ttatttactt tctcaaatgt aagagaacga gttgaaataa
    70261 aatctgaaaa tgtaacatta tttcaaacta taaaatcatt aaaagaaaat aaaccttgga
    70321 aactatttgc cttaaatata ttattcatgt ggactggatt ctttatacaa tctagtgcat
    70381 taatatatta cttttcatac aatgttggaa gtaagtcgtt ggcaacaaca gtggctacaa
    70441 ttatgtcaat aataccaata cttgcaaact tcttagtccc aattctagct aaaagattag
    70501 gaaaacgtaa tctatacata acttcagcag ctgtacaatt tataggtcta ggaataatac
    70561 taatagctaa tttaaatata agtttaatta tagcaggttc tatagtttct gcctttggat
    70621 atggaataaa agaaagtata tacttctcaa tgcaggctga ccctgttgat tatgggattt
    70681 ggaaaactgg gataaataca actggaacat taaactcagt aaatggattt ttaggaaaat
    70741 gtgcacaagc tatatcaggc ggtttaggtg gagcactcct agcttggggt ggatacatag
    70801 ctaaagcgga agttcaacca gcaagtgcat tagtagctat taaaataatg tatgtttata
    70861 ttccaatggc acttttaata tgctcaatga taactatgaa attttatgac ttagataagc
    70921 aatatcctaa aatcaaagca gatttagatg ctagaaaaat aagtgaggaa taaataataa
    70981 tgacacaatc aaggagaata aacatgtcta atattacaaa tagtataaaa gacttcagaa
    71041 tggaaattaa tcaagatttc atagataaag cagaaaaact aaagccaatc cttatagaaa
    71101 aactaattaa acctaagcaa attgttaata ttaaaatggg taaaaatgat tgggaggtta
    71161 tagatacaaa atcaatagat gaaatatcta atataagttt aggtaaagga gagagcattt
    71221 gtattgactt tggaaatcac caagtgggat atgtaaattt taaaataaaa ccaataggta
    71281 gcccaccaga tgcacctact catttaagaa ttaaattggg agaaacatta tgtgaaatag
    71341 gagaggatag ttcaacttac aaaggaagca taagtagtag ttggattcaa gaagagacta
    71401 tgcatataga tattttacct gataaaatta atatgaaaag aagatatgca tttagatatt
    71461 tggaaataaa ggtattagat acatctccta aatataaagt aatagtagaa gatgtatctt
    71521 gtaattttgt atcgtcagta gatatgtcag agataaatta tctatcaaat attgatgatg
    71581 acttaattaa aatcgataaa atagctttga aaactatgca agattgcatg cagactgttt
    71641 ttgaagatgg gccaaaacga gatagacgcc tttggatagg agatttaaga ctacaagcta
    71701 taacgaatta tgaaactttt aaaaataatg atttagtaaa aagatgttta tatcttttcg
    71761 caggattaac tcaaaataga ggccaagtag gagcatgttt atttatagaa cctaaattat
    71821 tagtggatga tactgcttta tttgactatt ccttattctt catatcatgt ttacatgact
    71881 actatgaagc aactaaggat atggaaattt taaatgaatt atggaaagtt gcatacattc
    71941 aagctaagtt agctttagaa agagttggaa ttaatggtgt tgtttatgat agtgatgatt
    72001 ggtggtgttt cttagattgg aaagaagggt taaataaaca agcaggtgca cagggagtat
    72061 taatatatgc tttaaaacaa gctcataaat tagctataat attaggcgat aatgaaaaaa
    72121 aagaagagct tgagtatgaa atagatagag tggttcaagg tgctaaaaat catctatggg
    72181 atgaaaaaca aggattcttt gtaagtggta gtgaaaagca agtttcttgg atatctcaaa
    72241 tatggtgtgt tcttgctgat gtatttgata aagaaacaaa tacaaagata ttagataact
    72301 tattagataa tccacctgat atggatatag ttactccata tgcatatcat catttagttg
    72361 aatgtttaat attaaataat agaaaagaaa aagctcttga atgtataaga ggttattggg
    72421 gtgaaatggt taaggatgga gctgattgtt tctgggagct atataatcca aatgataaat
    72481 atgtatctcc ttatggttca aggataataa acagctattg tcatgcctgg agttgtacac
    72541 cttcttattt tataagaaaa tattttggaa gagatagtaa agaagtaaca agcaagtata
    72601 aatgatattt ttttgtatct taaagagaaa tcaaactcat tatataaatt tgtaatatta
    72661 tataatgagt ttattaattt attacaaagc atagtctttg aaaactttat gatgagttta
    72721 gaaaatttta aaggtgatta ttgttgataa tctaaagttg cacttttata gatatagcat
    72781 caccaatatc atgtgtaacc aaaatagtag acttattctc attcttaata atactataaa
    72841 catcatcaca aactagtagt ctagtctgat aatcaagagc tgaaaaaggt tcatctaaaa
    72901 gtagaatatc tggatttaca gaaagtgttc taataagcgc aactctttgt ctcatacctc
    72961 cagataattc ttttggatac atacttctaa aatcccataa tccataggtc tttaaaaggc
    73021 tttcaactct atctaaagat tttttatctt ttttgccctg aatttccaat ccaatagtta
    73081 tattatccat tatatttctc cattcaagca aattatcttt ttgaaacata tatccaatat
    73141 ttccagtaat ctttatatca ccactagttg gttttaaaag attagtaaga atatttaata
    73201 ttgtagattt accacttcca gaaggaccaa gtaaagttaa tatttctcct tctttcaagt
    73261 taaaattgac atcttttaat acttcaagct cgccttcctt agtgtagaag ttcatattta
    73321 tatttttaac ttctactatg ttgtcattca ttatgccacc ccctataact tttagctcgt
    73381 atatattatg ttattaacaa tatgacctat ttgtaccatt tttcataaat ataatataaa
    73441 tattttgttt atttacgtat tttcttagta acttgtacgt ataaattata gataaataaa
    73501 ttataaggta ggggataaat ttgagtaaca taataacgaa tttaatagag tcaatattta
    73561 ctaatccaat aactatattg tttttacttg caataactgt gtattctgtt tttaaaataa
    73621 tagaaaataa cagagtatat tcatttgtaa gttcaaaatt agacgaaatc aatagagact
    73681 ataagacaag tgagttttat aaaaagataa gggatgacta ctatacatat agtaaagaaa
    73741 atccttatgc agacgtaaat ataacttcat ttatagagga agttgtatct gatttaaagc
    73801 ataataattt accattgtta gaaaagatta gaagtataaa aaattcatct tcaataagta
    73861 tattacttgg agttttaggt acgtttgttg gtctttctac aatgctttta tgtgttgata
    73921 ctaaagacat tataaattca cttccttcaa ctattagtag tatgcaaact gcttttacaa
    73981 ctagtatatt tggagttgta ttttctctaa ttataggtta ctttactaag ataaaagatt
    74041 gtgaacatgt tttgatacaa ataatgttaa agtctgaaaa tttactaaca tctgaaataa
    74101 ctcattttaa gtcagaaaga atagatttaa aagtagaaga ggtaaaaaat acaataaaac
    74161 aaataagcaa gtctatagaa gctattgaaa aattcgataa aatatctaaa gacttaaatg
    74221 actttaatga tgaatttatt agtggtatag aagctttaaa aagcctttta gaaggttctc
    74281 agagttctat taagacattt gaccagagtg taagaaaatt agataagcaa tttaatattt
    74341 taaatataaa gtttgtaaag ctttttgata aatatgataa tcaagataac ataaataaag
    74401 agattttatt tgatataaaa gaatcttcaa aaaatatata caatgccact gaaagtcagt
    74461 tcaaaattag agattatata aaaaatataa atgcaggatt tgccctatat gaaagaagtg
    74521 ctcaagattt attaactaaa ttaatgactc atgaaagtaa aatatctcaa aaccaaaaaa
    74581 tccttttaga tgaaaagttt accttagatg actcaataaa aaatctttca aatattattg
    74641 aaaacttttc taatgaccta caagttaaac tggatatgat gtttgaaaat tctttagata
    74701 ttcaagataa gttagatgtt atgtttaata actcttttat gaatgatgaa gttcctcttg
    74761 atagtgaaga attatttaat gatgatgtta ataatgtatt taatcctttt agtgaagaaa
    74821 tttatgagat agaggataaa gaaataaagg tcataggtga ggatgagtta aatgaataat
    74881 aaatatagaa gaactgttaa cagagaattt gaaaagagta gcttttggcc aacatttaca
    74941 gatttattat ctactgtatt gatggttgtg attcttatct tatttagctc agaaagtatt
    75001 tcaggttctg ttgaacaaga tttagctaag aatgtcaata cttctgttga ggaaactttt
    75061 aaaaaaagtg gaatacctgt gaaagtagat aaatctaatg gtcaagtaac ttttggtgaa
    75121 agaaccatgt ttgatataga tagtgatgtt ttaaaaccag aagctaaaga gatgttaaaa
    75181 atgttcgttc caaagtacat ggagactatt tataaagatt atggagacta tatatccaaa
    75241 atagttatag aaggtcatac agatgatgtg ggaagttata tatacaactt agatttatct
    75301 caaagaagag catatagtgt tgctaaattt atagtgggag atgaaatagg tgactataaa
    75361 tacaaagata aagtgactaa gcatattatt gcaataggaa gatcaaaagc tgaactcatt
    75421 aaaaatggtg ataatagcgt gaatagagat gcatctagaa gagtagaact aaaatatgaa
    75481 ataaatatta atcaaaataa ataattaaat ttttataaaa aaaaagaagg cagttggtgt
    75541 gagctttaag ccttctttaa ggaaaaagtt tatttatttt tgttgatact taacatatta
    75601 taatttttag aatcagtttg caatatatta aacgtaaatg gtcgtttaaa atgcataact
    75661 ggatactact gatataaaat atttcatttt atataatata aaaattatac agtgtcaatt
    75721 ttctatgtta ttgcaccata atctattatt taaaatatta tgtaaaaaaa tatcataaaa
    75781 acgcatatca tgttataatt actagagtat tatgaatatg gaggcgtagt ttgtgataga
    75841 aagaaatata aaaaataaaa aaaattctaa aattaaagct ttgatacttt tatttatagt
    75901 atctatatca atttatttaa ctggttgtgc tacatcagac aatggaaata atcaatcaaa
    75961 taataatgac tctttgtcta gtagtatatc aagtgataag aatgtaaaaa ttcattttat
    76021 taataccgga aatagtgatg caatattgat tcaagatggt aaaactttta cattgataga
    76081 tgggggagat aatgatgatg agaaattaat ggtagattat ctaaataatc aaggtgtaaa
    76141 agatattaaa tatcttatag ctacccattc tcatgcagac catttaggtg gacttgattc
    76201 tgttgtcaaa aatttcaata tagaaaatgt ttttgtatcg aatggttcag cagaaacaaa
    76261 gagttataga gactttataa acgctttagc aagtaaggat ttatctccaa gtgtaccact
    76321 tgaaaataat aaattctatt tagaagattc ttattttgag gttctaaata caaatggagg
    76381 agatactact aatgaacaat ctctagtcct tgtatatact aatggaaatg ataaagtttt
    76441 atttacaggt gatgctgaag aaggtactga aaaagaaata ctatctaaac ttgataaagt
    76501 agacctttta aaagtagctc atcatggttc tcgtagtagt tcatctcaag agtttttgga
    76561 taaagtaagc cctgaatatg cggttctttt agtaggcaag ggtaactcat atggtcatcc
    76621 acatcaggag acaatgaata aattaaaaaa aatgggagta aaagtacata gaagtgatga
    76681 gtgttcagat ataatatttg aatcaacagg tgatggagta tttacaagtt gtaaagatgg
    76741 aagttacaat aaaggcgtta gagaagatgg aaactctgga aaatcaaaca ataatacaag
    76801 taaaaatgat tcttttaaaa ataaacaaaa tacatctaat tcagcggaaa tagtgtattt
    76861 tactccaaaa gggaagagtt atcactctac aaaaaattgt agtgggcttt caagaagtaa
    76921 aaaaatatta tcaggcacaa ttgcagaaag taagaaaaat gacccatgtg atatatgtta
    76981 tgtaaaataa taaaaaatca accatttata tataaagctt ctgagctaca taaaaaaata
    77041 agctataatc aatagataac acattttatc tatacgaata gcttattttt ttatgtattt
    77101 tttaatagct atttaataac tctaaataca ccagttacaa tgcctacaat ttcaacttct
    77161 gagtcattga gcataattgg ttccataaaa tcattctccg gctgaagtct tattaaattt
    77221 ccttctttaa aaaatctctt aactgtagca gattcaccat ttataagtgc aactactatc
    77281 tgagaattaa aggctgtatt ttttttgtct actacaacgt aatcttcatc taaaattcct
    77341 gcattaatca tactttcgcc ttttactttt aatacaaaat tgttactgcc ctttactaaa
    77401 ctggcaggga atggaatgta ttcctctatg ttttgttgag ctaaaatggg ttctccagct
    77461 gttatttgac ctactaaagg aagttctatt atttcttgat tagctccaga aacatcattc
    77521 actttactac gttctaaaac ttcaatagct cttggtttag tagggtcttt tcttatgtat
    77581 cccagttttt caagtttatt tagatgagag tgcacagttg aagtagatct taaccctaca
    77641 gcagtacata tttctcttac agcaggtgga taacctttta atattatttg agactttata
    77701 aattccaata tcaatacttg cttttcagtt agatctaaat acataacatc actcatttcc
    77761 aaacatattt tgtttttatt tccatacact ttatattttt aattataaca taatccattt
    77821 atatctgcaa acatttgttc ctgattttta atcatcctca atccattcaa aattcttgac
    77881 tatatcacgt tttacatttt tcttgtgagc tgcataaagt tgagtagttg tgacattatc
    77941 atggtcaagt aagttttgaa catcatatat agaaaatcct gtttggatta gagaagtcgc
    78001 agctgttgcc cttaatttat gaggactata tccattttct ctcgtagtat caagtggaat
    78061 agatgtatat ttttttacta gtgttcttat agcctttgct gtaattctct tattttgaag
    78121 agataaaaat aaagcatctt tttcttcatc atttaatagt tcatctcttg ttctttcatt
    78181 ttgcaaataa tcttttatta catgttcaca agtatggttt ataggcatta aaacttcttt
    78241 tccgcgtttt ctatatattt taaattcacc tcttgaaaaa ttaaaagagg agatattgag
    78301 ttctctaagt tcatttaatc taagtccata tgtaacaaat aatgctagta tagctttatc
    78361 acgtaactta gtttttctcc aatatacctt ttctttttct gtaagccctt cacctgtttc
    78421 tactgattca agcatcttag caacttcgtc tatctcaaga cgcttaatgg catctggctg
    78481 aggtttagga agctttattg gattgaatcc atccgttata ttattatcta tctgagagtt
    78541 cctgtataag aatttaaata gagtagagat ggatgatttt ttccttgcca aagctctatt
    78601 gttattttca aaaatcaatg tgtttttttc tgtattttta taatatctac tacaataatc
    78661 acccaagaat aaatttatat ctcttgattt tattgtatta aagtcatctt ctgtaatatc
    78721 ttttatacat tctgcatttg ttaattcttt ggtttcaatc aaatatgaac aaaaaaaatt
    78781 aatatcttct aaataagcaa gtcgtgtaga aactgcaaca gagcctttta gatatataaa
    78841 ataatccttc ataaatacag gaagtttatt ttccaaaagt agacattttt ctatgagttc
    78901 attttccttg ataacaatat tatcaggttt atctgattta ttatgtactt ttataacttt
    78961 cttatcatta ttcaaaatta aacctcctaa aactaaaata taaatctttt atattatttt
    79021 ttaaatattt atactgaatg agtataaata tttaatttaa tcattttttg catttttaag
    79081 agattagcag tgctttaatc gaaattctta ctaactattc cctaaatcca catttaaaga
    79141 ctagttgagt ttgagtactc tttttttatt tctcaatata tttatagaaa tattttaaaa
    79201 tatattgaga aattttttat gctctactaa aatctttttt tatataatat ctttatatgt
    79261 tttaacaaaa ccaaatatta gtaaaatatg tatttattta actaaagttt ttaaatggac
    79321 taaccaagct taaaatatag gatattataa gagttactat tgaaaaaata agccctattg
    79381 ccataaataa acttacaaat atattgtatt taactattaa actggatata tttaagttat
    79441 caaatccaaa taagtatgta attagactta ttgcaaaaat aactatgact ataaaactca
    79501 aaccatttaa actatttttc aaatcagcac tactaagtga catatgtgta gatatagaat
    79561 acattaaaaa cataaatata aaatacttta atgaatatac actaggtgtt aacaacatta
    79621 ttcttataaa attagaaata tcgcctaaaa taatgtatat aaaaccactt atgtctaaat
    79681 tattaatcat acttacatat aaatttaaat ctatattttg agtcactttc atataactat
    79741 ctggcaataa tatcttaaaa attaaaataa tcattactgt tccacctata ataggtgcaa
    79801 ttcctataaa gaaatttcct atactttgat aaagattatc ttttttataa ctatgactta
    79861 catatcctag tataccatca tttttacttt ctattggtct gaaaaactta actgaattta
    79921 ttttatgcat aaaaatcaaa cacattatca aatgactcaa ttcatgaaca aacgttccta
    79981 tagctccagt tacaataatt ccaatttttc caaaagatga aaagataaat ttattattta
    80041 gactttctgt aatgctaaaa atcaatccaa atacaataaa tattcctatg aaacaaaaaa
    80101 tatttattat acttattttt aaaatttcga ttatataaat cataagttaa acctcatgta
    80161 aaagtattta actactctac ttcatatcca ttacagttta aaattttaca agcattttct
    80221 atatcttttt cttttactaa tatatagtct gtatcatatg tagaaattgc aaatatgctt
    80281 attttattat ctgctaacaa actacttaac ttagataaaa ttcctacaag tgaaaagtct
    80341 aaaggaccta atatcttaag tattctccac tccttttctg acttaacatc agaaggaata
    80401 ttattattta agcatacaat acttaattca tcatctgttc tagttataga gtaaaacctc
    80461 tctgtatcta tccatgttgg tattttagta tcattattta atctacatac tgcatactct
    80521 tctaccaata attttaattt cataatgtat atttcctcca atcttatttg tttacttaag
    80581 attatacatt aaaagttaca taaaataaaa cagataaagt aaaaaaggtt cactatagtg
    80641 tcctatttct atagccaacc tttaaaactt aattaaattc taataaagag atatattatc
    80701 taggttcaat tataagttta atggctgttt tcttatcacc ttcgatttct atatcagtaa
    80761 atgcgggaat gcaaactaaa tccattccac taggtgcaac aaaacctctt gctattgcaa
    80821 ttgattttat cgcttgattt agagctccag ctcctatagc ttgtatttct gcaatgcctc
    80881 gttctctcag tactccagcc aaggctccag ctacagaatt aggattagat tttgatgaaa
    80941 cttttagtac ttccatttca acatctcctt gttaatttgt taaagtatcc attacctaaa
    81001 gtactaaatc ataattgcca tttactaatt acaatcatca tttaaagtat acttttataa
    81061 aaatatactt ctataatcat tttaagaaaa cctttatttt ttttaaccat tttataatga
    81121 aaaaactaca aatttcttta tattctataa gcattttcca atatttctaa atttagtata
    81181 tctttgagct ataatttcct ctttatccat gtctttgtaa tgatttaatc tttctaaaat
    81241 ataagctttt atttcttttg aaacagcctc tacatctttt tgtgctcctc caagaggttc
    81301 ttttataatc ttatctatta tttttaaatc atataaatca ttacttgtaa gtttcataac
    81361 atcacaagcc tctttagctt tagacgaatc tttaaatagg atactagaaa gtccttctgg
    81421 agaaatcaca gaataaactg aatgttctaa catacaaacg tcatttccta ctccaatacc
    81481 caaagctcct ccactaccac cttcaccaat tacaaaagtg attactggaa cagaaagttt
    81541 actcatttca agtaagtttc ttgcaatagc ttctccttgt cctctttctt ccgcttctag
    81601 accacaaaaa gctcctgatg tatcgataaa cgttattata ggtctattaa atttttcagc
    81661 ttgtttcata agtcttaatg cttttctata tccctctgga tgaggcattc caaaatttct
    81721 ttttatattt tctttagtat ctcttccttt ttggtgacca actatagtaa cattaaattt
    81781 tcctatctga ccaattcctc caactatcga agggtcatct ttaaaaagcc tatcaccatg
    81841 aagctctaaa aaattagaac aaatatgttc tatgtattcc aaggtcgtag gtctttttat
    81901 atctctactt agcattacct tttcatatgg tgataaatgt gaaaaagcat cttctttaag
    81961 cttctccaat ttctcattaa gtgaatttat tttatcactt aaatctatat tatttgcctt
    82021 agaaataatt attaattgtt taatatcatt ttctaagact tttatttttt cactattatt
    82081 ttcaatcaaa acagttcctc ctttatgccc tatttcttgt gcatagcaag aatttgatat
    82141 aatacttcct tcatttttct tctatctact atcatgtcaa taaaaccttt ttcaagtaaa
    82201 aactcagaag tttgaaatcc ttcaggaagt ttttgattta ttgtttgttc tattactctt
    82261 ggacctgcaa aacctatcaa agtatttggc tcagaaatta taatatctcc aagcatagca
    82321 aaactagcag ttactcctcc agtagtaggg tcagttagaa ctgatatata tggtaatgat
    82381 ttttcttcaa gtttagaaag cgcttgagaa gtctttgcca tctgcataag agataccata
    82441 ccttcttgca ttctagctcc tcccgaagca gaacaaataa tgataggtaa attattttca
    82501 gcagcatact ctattgaata agttattttt tctccaacaa tagaacccat acttcccatc
    82561 ataaaatcag gattcattac acaaataact gttttaattc catttattct tccataacct
    82621 gtgacaacag cttctgactc ttttgttttt tccttataag agtctacttt ttctttgtat
    82681 ttaggaaaat ttagtggatt ttgaaattct acatcagaat taaactccat aaaagttcct
    82741 ttatcaatca ataaatttat tctttttctt gctcttaagc cataatgtct tgaacatttt
    82801 ggacatacaa atgaattttc ttctatgtcc tttctaaata catgactatc acaacctttg
    82861 caataggtcc aaaatttatc atctacacta ttctttttaa agttgtcatc taaagaaatc
    82921 gtaacatact tagattcttt tgatgataaa aattttttta tcataatcta tttactcctt
    82981 ataatgtagc aaattctttc ttcataaaga catcttctat aaatttggta tgatgagtat
    83041 cttctctaaa ctcctcactt gttacaagtg ccttttgaaa ttctacattc gtattaatac
    83101 cttctacaat aatttcgtct agagctctat atattctact tatacattct tctctagttt
    83161 cagcccagca tattaactta cctatcatag aatcatataa aggtggtata gtatatcctg
    83221 catatacaaa agtatcaaat ctaacaccaa aacctccagg taaatttaat gattctatct
    83281 tacctggtga tggagcaaaa ttctttgatg aatcttctgc atttattcta cattcaatag
    83341 catgacctct aaaagtaata tcttcttgtt taaaaggaat tttatcccca ttagctatag
    83401 atatttgaag ttttataagg tcaagatttg ttaccatctc tgtaactgga tgttcaactt
    83461 gtattcttgt attcatctct ataaaataaa agtttttatc tttgtcaact ataaactcaa
    83521 tagtacctgc acctatataa cctacacctt ttactatatc tactgcaatt ttatgaagtt
    83581 tttgtctttc ttcatctgaa aggtatgggc ttaaggattc ttctattact ttttgatttc
    83641 gcctttgcat agaacaatct ctatcaccta aatgtattgc atttgaatgt ttatctccaa
    83701 atacttgtac ttctatatgt ctaggatttt ctataaattt ttccatatat aaatcactat
    83761 tagaaaatgc tgctaaagct tctgaacttg ccatatcaaa atttgaaaaa agttcttctt
    83821 cttttctaac gattctcata ccttttccac cgcctccact tgaggctttt atcataacag
    83881 gatatccaat ttctcttgca acttctaaag cttcttcctt agttttcaaa acagattctg
    83941 aaccaggaac aacagggata tttaattcca tcatagtttc tcttgctcta gatttatctc
    84001 ccatcaaaat catttgttct cttgttggac ctataaaaat aatattgttc tcttcacatt
    84061 gttttgcaaa ttcgggattc tctgataaaa atccaaagcc tggatgaata gcatcacact
    84121 ttaatttaag agcaaggtat attatatttt ctatattatt ataactctta cttatattat
    84181 ttggtcctat acaaatagat tcatcagcta tatatctatg aaaacaatct ttgtctattt
    84241 cagaatagat agcaacagtt tttataccta gttctttaca tgttctgatg attctaactg
    84301 ctatatcgcc tctatttgca actagtattt tttttatcaa cttaaatacc tcctactaca
    84361 atggttttat cttaaataaa ggttgattat attctactag ttcttcatta ctaactaata
    84421 cttcaattat ttcaccttta atttcacttg ttatctcatt cataagcttc attgcttcta
    84481 atatacataa agtgtcgcct tcttcaacta catcgccaac cttaacaaaa ttatctgcat
    84541 ctggacttgg agaatcatag aatgttccca tcaaaggagc taccactact gatagattct
    84601 cattagatgt gacaggtgta tcgtttacaa ctggcttttc taaagaaaga tccactactg
    84661 attcttgttg tacacttaaa acaggtgaac ttgtagcttg agctttttta gatacttcta
    84721 atcttaaatc gctactttca agttttacat attctaagtt agttgagtct atggccttta
    84781 ataattcctt aatttcattg atgttcattt tgttaccccc ttgtattatt acctggtgct
    84841 aatattatat cacaaaaaac aaatttataa aagaaaaagt gctgactaga caatcaacac
    84901 atcaatatat cttttaattt taaattaaca accagtaact tatatttgtt ttaattttcc
    84961 attattaata taaattataa gtataaaatg aataaaattc aatatttttt gcaaaataca
    85021 aaagaataca aattaatacc tcgggaattt ttaagacaaa taccaatatt atgcaattta
    85081 gacttcactt tctttcaaat tagtatcatt tcctttattc ttacatagga tatactttaa
    85141 tttagctatt aaaacattac tatataggtt aaaagttatt aaaatcgcag gaattataaa
    85201 gtaaactcta gcacctataa aaccaaaaac tactgtagta agtattaatc ttttatttaa
    85261 agtaaaaaaa ggtatattaa aaatactttt gtctgatgtt tctggagtat aagaatatat
    85321 aactccaaaa atcaaagtca acatacaaag tggaagtagt gtataacttg aaattattcc
    85381 cagaaatcct atactttcaa agtatttgct agcactattt gtataaacaa acatgtatcc
    85441 atttaagtag gcgcatatac atgatataat gccaaaagtt ccccctaagg attgagtgta
    85501 ccaattaaaa aatttagatt ccatatacct cacctcctaa aactgtatat ataatgatat
    85561 gcatttaaat aatgaaatat atctttatgt gcttatgaat aaatttttgt taatttcatt
    85621 aatttatgtt taagaaattt gaagtatagt gtagtatata ttaatgtaga taaaatttta
    85681 tggtacttat tttatagtgc ttaatcaagc tatattatta tagatttaaa agttgttctt
    85741 agggttttat attttgttga gctgaaaaat ttattataaa tgaagggatg ttttcgcttt
    85801 ggtagataca ttagaatttg gtcttaaaat tttatttttt atattatcaa taatttggat
    85861 gggtaaaata atgattttaa gaactgataa gcaaatagta ataaatcctt tgcttattgg
    85921 tatatctgca gtccttgtga tgttgcatac ctcacagagt aacattgaat tttttggatt
    85981 agatgtccag tatataagaa tagttttgta tataatatat tcactgataa ttttaatagg
    86041 aatatgggct actaacagaa gaaatggaat tttttaaata atctatttct ataaaattta
    86101 aaggttgcta gtaacaaagc gctaatatta gtgttctgtt actagcaacc tttattttga
    86161 ttatacactt aaattgaaaa tagaatgact aaataagttg acagattatt ttacattgac
    86221 agtaattaga acttcttgag atgtatttaa atcatttttg tcgtttagta taacttttac
    86281 tactgcttga cctgttttat tacctttgat tatcatatcc tcacatgaaa gtacactctt
    86341 atcacttaca gatacaataa aatctaaatc ttttggaagg ttatcagtaa cttcccagta
    86401 tttataatag ctatcaattt tcttcgtaat tatttttctc aaatcaatac tttcaccttt
    86461 tgctatatta acattatgat atttagagtc cagtttatac tgattatctt ttgtatcgat
    86521 aaagtttaaa tcgcaattta catccacacc attatgagaa agagaattta ctacactgtc
    86581 atcaatcaaa taattattgg caagatttat tgaatccata tcttttaaac ttaaagcttc
    86641 tttaggaatc tcttttatat tattgttcca aaaaataaaa ttgtctacat tttcaagata
    86701 tgatattcct tttaaatttg aaatgctctc accagttgca taaaattctc catctaaagc
    86761 ctttatattg cttatagtca tctcatctgg gtttatatat ctttttacaa ctgctcttaa
    86821 atttgcatca ggaaaaatat ctttaagttg attttcgctc aaaaccttat catttgaatt
    86881 tattggactt aaagctgctg cagaaataat aaatggtatt aaattagcta aattcatagt
    86941 accctcccac ataatttttt tattataata atttaatttc tatgagaggg ttctgtttcc
    87001 ttgttatata tgcctacttt cgtacacttt attaatataa attaaaataa atttctacta
    87061 ttaaacttat aaacatatta ctagttacgt tttttagctt cacatctaaa tattcgcata
    87121 ccttgtgaca taaatttgtc ttcatactct gttgtaacat tattttcata ctcactattt
    87181 cctaaatcaa gagaaatatt ctttaatagc caattatttg cagcaatttc atttaaacta
    87241 aactcgaata atttttcatt atctgtttta aagtgaattt cgccatcatc ttccaaaacc
    87301 ctattgtaca tttctaaaaa tccagaatga gtgagtcttc ttttactcca tctattttta
    87361 ggccatgggt cacagaaatt tatataaatt ctcgataatt ctttagcttc aaagtaatcc
    87421 aaaatattgc ttacatctcc ccataaaaat agtatattat tcaaattaga agcatctgct
    87481 ttttcaacag cctttaaaag aacttcttcc ttaagttcca tggcaatata atttatgtca
    87541 gggttctgct tagctaaagt tgttataaac ttaccttttc cagtcccaaa ttcaacatgt
    87601 attggattat catttctaaa ctttaaattc cacttgcctt ttaatttgtc tatatcgtct
    87661 cttaaaacat attttgtata acttaaaagc ttttcatctg cacctttttt tcgtcttctt
    87721 ctcacaataa ttctccttac atataaaaaa ttagtaaaat acatttttat tatacattat
    87781 ctcaccaaaa aataaaaaga actctcttaa aatagaaatt tatttctata aagagagttc
    87841 taaacttact aaaaacttaa tcttagtggc accctgaaca accagagcat cctcctccac
    87901 cttgatcttt catattttca ggaataactc taaatccaaa tcctgtatct tctattatta
    87961 tatctccata ctgactatat tcatcagagc tcattacaaa ttgtaattct ccaacttcat
    88021 aagttaagtc atcttctttt ttctcatcta aagctaatcc aaaagaagga cctccacaac
    88081 caacacctgc aaagtatact cttatattat taggtttatc ttgattgtct tttaagatac
    88141 tttttaaagt atcgatagct gtttctggta aagtaatttt catcaaatca ttccctttca
    88201 aatattttat taaaacaata tctattatat acccatacaa ggtacataat caattagttt
    88261 ttgcatattt tactaaaact tctacctaat attacctaag gctttaaaat attttatata
    88321 atattttatt accttaaata aataccctat cataaactta gtaaacaaat aaaattatta
    88381 ttctaaaaaa tataataatt ttatttgttg ttttaatatt ataacacatt tgataatgtc
    88441 caattcatat atgcaaaatt tatatacttt aaatgattat ctcaaataca ataattagcc
    88501 cttatacaat taaaccatct gaaactgtaa tagtacgact actacttttg gctgcttctg
    88561 gtgagtgtgt taccataatt atagtttgtc cattgtccct gtttatttta tccagtaaat
    88621 ctattatttc tatccctgtt ttactatcta aatttccagt aggctcatca gcaaataaaa
    88681 tctctggttt tccaattaaa gctcgagcta tagcaacacg ttgttgctga ccaccagata
    88741 actctcgtgg tgtatgttta cgtctatcag ttaaaccaac tatatataag atttcatcta
    88801 attgattttt ataatctttt aaatttttac catctaatag caaaggaagc attatatttt
    88861 cctccacatt taaatttggt attaagttat aaaattgaaa tacgaatcct atatttctac
    88921 gacgtattat gctcattttc tcatcattaa aatgtgatat atcagctcca ttcatataca
    88981 cttttccact cgttggagta tctaaaccac ctaaaatata taaaagagta cttttaccag
    89041 aaccagattg acccatgata gaaacaaatt cacctttcat tacttgtaaa gacacctctt
    89101 ttaacactcg agttgttgta tttccaattt tatattcttt gataatattt tttgcttcta
    89161 cagctaaact attatgtgta attttcatat taacctccat aattattcaa acttaatttc
    89221 ttctatcagt ttcattttct tcccttttat aataggcact atcgaaccta ttaaagttac
    89281 tataattccc aataacccaa caataataaa tgttttaaaa tctaaatctg gtttcattga
    89341 aatttttggt cctgcaacta taaagatagt ttgaatctca agtatagata ttacaatacc
    89401 aataacagct ccaagtaaac ctgaagtaaa cccttcaatc agtgtcactt ttatattttg
    89461 tttattactt agtcctatag atttatacat agctatagaa cgtctttttt gaatataatt
    89521 aatcagtaga ttattaataa tacctactgt agcaagaaga aaaatgaaat aggtcatctt
    89581 attcatagga gacaaaaaac tacttatagt atttaaagaa tcattataaa attcttcaac
    89641 tgtacgactc caattatatg tatctccaaa taaatccctt atctgaatca taacagcatc
    89701 tggattgact gctgtatata ctaaaaaacc ataattagtt ttatcaaaat cattaactgc
    89761 ataatgtgat ggtataacag cttctacatc atttgcacga gatttaaaac tacctactat
    89821 tttataagaa aaatcatact tatctttaga tagagttatt gtatctccta tagataaccc
    89881 tacttttttt agagtatctt cattcaaaat aacagaacgt ttatccttaa aagcttctgt
    89941 tacttgtttt tttatctcaa aatttgtata attgattgcg aacatagagt tatatagttc
    90001 tatattatct gtaccctcta gtcttgataa tgttacacca ttaccagaaa tctcattatt
    90061 cataacataa agaggtaata tgtttttaat tccatccata tgtctaacat cttcaataaa
    90121 ctcttcattc atctttccat ctgcaaaacc ttgtaattct gcgtcacgaa acacatctgt
    90181 tatataagtt ttgacaaagt taccaacaac gcttattgca ataactgcag aaatacttat
    90241 aaatagtaaa gtgatattct gtattatatt tttgttattt ttcatatttc tagcagctaa
    90301 tttaccttca ttccctaaaa tatttttata aacaaactca aaaactatag acatgatatc
    90361 agtaataaga ggaatcaaca caatagtagc tacaattaat cctagtaatg aaaatccgcc
    90421 agctagatac aatgtatttt caggggatat tcttggaagt aaaacagata aaataaacat
    90481 tatacttcct ataaaaagta tagaacgatt tgaaacattc ttttcttcta ctgttcctag
    90541 tacaatattt tttattggca aatggctagc ttttttaaca ggtatatatg cactaaataa
    90601 agaaacgatt attgctacta taacagatat aatcactcca atgggtgata ttactgttgg
    90661 aattgatatt ccttgttcga gagaatttcc taacccatga agcattaaat ttaaaacaac
    90721 tacaccaata ggaatagcaa ttaatcctcc tatacttccg tataatatac tttcaagcat
    90781 caatatatga gttacagttt tttcattggc accaatactt ctaaatgttc caataaaagg
    90841 aagacgttct aatgtaataa ccttataact gctgtatatg ataaatatac taagggttaa
    90901 tgcaaaaaaa cttattaaaa agaaaggcat tatcttttgt ctagcatctg aaattatctt
    90961 agtttcattt atagtatttg atactgtata tttttcagta gaaagttctt cggataattt
    91021 atttactaga ttttctgtca tttcttcttc tgactctata agaactcttg tatatccact
    91081 gcctttattt ataatttttg atagagtctc tttaggtagc agtgcattca cacctcttgt
    91141 atgcctcaaa aatactgtat cataagatgc aatatcacta acttgaaaag tataagactt
    91201 tccataaatc tgtaaagtaa tagaatcacc tttttttatt ttatattttg atgtaaaacg
    91261 gtttggaaga ataattttat caccagaaaa atcagtaata ctatcgccat tttctaatcg
    91321 tggcttgttg attttattta gttgacttaa gtctgctgct ataagactaa attcttcata
    91381 gtatcccccc ttattataaa tagcagagct ttccaataca ccaacctttg attttatagc
    91441 atttaaatca ggtatgtctt ctaaattggt taatatatct ggatttttac tttggacaga
    91501 tatagtcgct gtaccagaca taccttttgc catttttctt tgtgcacttt cataagataa
    91561 tccaatcgag aatgaaacaa aaagtaaaac tgttgataaa actatggaca ataacataac
    91621 tgctgttcta atttttcgtt ctttaatatt tgtgaaaata tactttaata taattttcaa
    91681 atttacacct tcttccttta tctaagatat ttcagtataa tatttttata ctttaatcca
    91741 aattgaatct ctaatagact cctccatact tttatcattc tatttataat atttttaatc
    91801 aaatcacctc cttaaataaa aaagattgat aaactactat ataaatataa taatctatca
    91861 accttaatat attttttatt tgaccttaat taaccttaat taaataggaa agatgatata
    91921 aaatgaacta cccaatccaa gtatactttc aacagatata ttccctccat gaacttcaat
    91981 aatttgcttt gttattgcta gtcctaaacc agttccttct atttttgttt tgcttcctct
    92041 ataataccga ttaaacaaat ttgatgcctc ttctcttgac atcccctttc cattatcaga
    92101 tataatgatt tcaattcttt catttaatgt tatatgtaca caaactttag tatttttatc
    92161 tccatatgta aaagcattga caataagatt actaaaagct cgttttaata gtgtataatc
    92221 aaaatcaaag ttaatattat ctatattact cttaaattca actatatttg attcatattc
    92281 tggataattt aaaatatcaa tggataattc tttcaagagt cttactaaat catagttatt
    92341 tttatttaaa gggattattc cattttttaa ttgataggtt aattttaaat cgtttataag
    92401 tgtatttgta tattctatgt tctttaacat gattgaagca tatttatata ctttttcagg
    92461 tgaataatta atactactat ctgtaagaag ctctgcatac ccttttattg gtgaaagtgg
    92521 agtttttaaa tcatgagtta tatttgaaat ccactcttct ctcataatat cagttttatt
    92581 ttgtatctca tcacttctat gaatttcttc atttaaaata tttaaactat catatatatc
    92641 agtaaaaaca cctttaatat taactggaag atagcttcgt tttgaaatat cactaacagc
    92701 agatgtaata tttgatatgc actttgttac ccagtaacca taagcaattc cagaaagcaa
    92761 aattattaaa aatataatcc ctatgattga aaatacaatt gacttaccac ctacaaattt
    92821 acttccatca aaaaacatat tcactttaga tatatttaat ggaaaatata taatataaat
    92881 atagtcattt ttattatttt taattgcatt aaagtataca gttccattac ttgaattatt
    92941 ttggttagct aatgttaata attcagaatt agaataataa tctttatgct cttttggttc
    93001 taaaaaccca taaactctat ttccactaga atctaaaatt tgcaaccaca attgattttc
    93061 tcgaagcttt tctaatccag actgttttac ttgtggctta ttatctataa atacgatttg
    93121 ttcattaaag ttttctgtaa attttttcgg ccagtcacta cgaataaatt ccccatttgg
    93181 tttctgaata gtaataagtg ataagaaaat acctattact gtcaggatta agcaaataaa
    93241 aatcataaaa aaaataatgt atgaatgaaa taccgtttta taactaggtt tatgcattta
    93301 atcaactctt ttcttaaact tttattttag tttgattgtt gcttatataa aatagacaat
    93361 aattattgac atgtaaaaat ttatttaaaa atacaactat ctacataaat tatatttata
    93421 taattatatg ttatcaagct gtccgttgta tttaataaat ccttttgata acatataaaa
    93481 gtaagataaa attttccatt aaatacctta taattataca caaaatttct atatacgtta
    93541 aacagtatag agaaattttt catagaacca tctttatagg ggatacttta taaaagaatt
    93601 aaaaaattat aatatataaa aaacttcata ggagtgtaac aacatcagta aagatataaa
    93661 aacactatat aaaaattcaa aaatattaag aataatgaaa tacttgaaat tgcttatatc
    93721 aagaaatttt atataatata aactggtcaa atatgttata atattaaatt gtgacaagtt
    93781 catggaggtg tttatatgaa aaaacaaaag tcgccaattt tacttgaaat gcttggacta
    93841 tttttgggtt gtatatcaat gagtattggt ataaatatgt ttttaaaacc acatacaatt
    93901 gctcctggag gacttagtgg tctatcatta gtactaaaca aggttacagg acttccagta
    93961 tcagctatca tgttaattat aggtgtccca ttagtgatac ttgcttttag aattatgggt
    94021 acaaaaaatt cattaaaaac tttatttgga acagttgtat tttcagctat agtccaatta
    94081 acagatccat tatcaaagct aagatttact aatgacttat tattgtcttc tattgcagga
    94141 ggaatcctag ttggtatagg tttaggaata atgtttaaat cagatgcttc tactggagga
    94201 acagacttaa ttgcactcat acttagtaag aagttcccag gaataaaagc tacaaaattc
    94261 atgtcatgcc tagatggaat ggttgttata tcttctggta tagtaaatcg tagtttagaa
    94321 actgcacttt actctggtat agcactttgt gtattaataa aaatagcaga tatgataatg
    94381 gaaggatttg accattcaaa agcatttttt attatttctg atgagcctga aagtttaaga
    94441 caagctataa ctgaagaact tgatagaggt cttactattc ttgatggtaa aggtggatac
    94501 actagagaaa ataaagaagt tctattagtc gtagtttcta aaaaacaaga actttatcta
    94561 aagagattag ttaaaagaac tgaccctact gcatttgtta ttgttacaga tgtgcatgaa
    94621 gttcttggag aaggatttaa aaatttagag aactaataaa aaattaatat tttaagtata
    94681 tatactattt taattaaaat acgatttatt caaagagagt gtctcataaa ctttttggtt
    94741 catgagacac tctcttttgt ataaaatcaa atgcattttc agtattttta caataaaaaa
    94801 caggcttatc tatattttga ggcaaccact ttattgaaat tttatttaga aaacaatcat
    94861 tattaaataa ctagcataaa tattaaatga ttatatctat tgttttttca attcatattg
    94921 ataacaagga acatttttta cagtatttcc agtatgaatt tttttgatat actttcctgt
    94981 acatttaaat cctaataaat ctaatgattt tgtagaattt tggttttctt cataggttat
    95041 tgcaattatt ttatttaagt ttagttctct aaatccatat tgtattactc tttttgttat
    95101 ctcagtagca aaatcatgcc cccaataact tggatttata catataccta tttctgcttc
    95161 taatgcttta ggatttatat tattaaaccc catattccca ataactttat tgtctttttt
    95221 atatactata gcaaaatgtc caattttccc ttttttatag ggatttagaa aaaatgattt
    95281 tataaacttt cttgtatctt ctaaagattt atgctcacta aatggtaaat gttttactac
    95341 tattttattt ttataacagt caaaaaaatc ttcgacatca tctaatgatg caggtcttag
    95401 tatacaattt ctagtttcta aggttttcat ttgaggatat tcagaatcag acatttctaa
    95461 tcccccttta tacattaatc taaatatact gttcatattt aaaatacgat attaattata
    95521 taaatgttct caaattaacc ttatttttat ttttaataaa aactaattac tatatgaatc
    95581 tttcaaattt acgaacttat ctctattttt atattaaatt acttgtgaaa tatgtattct
    95641 aaattatatg ttattagata tcatgcttaa aaattctttg gttgctaagg ataaagatat
    95701 atcttttaaa tggcagtaac ctatatttct cttaggtatt ggctctttta tatctaattt
    95761 aaacaatttc ccattttcca aataatctat gctaaattct tctataacac aagatactcc
    95821 tagatttata tacgcaaatt ctaaaagcaa ttcatgagaa cccaattcta tatccgggtt
    95881 tagttttata ccttttgata aaaaatattc atttacataa agtcttgaat ttgctttatt
    95941 ttctagcatt attaaaggca atgtatttaa ttcttctaat gatatttttc tccctttgta
    96001 ttctatgtaa tcatttgcac acacaaatat atcatgtatt tcaatacact caacaatatt
    96061 tagtgtatca tcttctattg gcatgtttat aattgctata tctatattcc catctttgag
    96121 taaagatata agctctctac tcgttctatt tattgtagat acatgtatat gtggatactt
    96181 cttatgaaaa atttctaaat attttaacaa gaaaaaacgt gcagctgtat ctcctactcc
    96241 tatttttaga gaaccatatt ctaatttttt aaatttattt attctatctt ctcctgatga
    96301 tattaacttt aatgcagtag tgacatgttc acttagaatt ttcccctctg gagttaattt
    96361 tactccctta ttgtttctat aaaataataa agtatctaat tgttcttcta gttgctttat
    96421 tgactgactt acagctggct gtgacataaa caattcctta gcagcaagag aaaaactctt
    96481 attatttaca actgcattaa aaaccttata aagttcaagt tttatattca tatataatta
    96541 ctccttatgt caaatattag tattatttat tttacttata attatatttg aattataata
    96601 tacatggtac taatatgaca atattaattc tttaggagga ttttagataa tggatagatt
    96661 agttggaact gtttcaagag gggttagagc acctattata agacaaggag atgacttagt
    96721 taaaatagtt gttgattctg ttttaaatgc atcaaaaagt gaaaactttg aagttagaga
    96781 caaagatgta attgccgtta cagaagctgt tgtagctaga gcacagggaa actatgctca
    96841 tgttgacaat attgcaaaag atgtaaaaga taaatttgga gatgatactg ttggggttat
    96901 attcccaatt ttaagtagaa atcgttttgc tatatgttta aaaggaattg caaaaggatg
    96961 tagaaaagtt gtattaatgt taagctatcc ttctgacgaa gttggaaacc acttaataag
    97021 tattgatgaa cttgatgata agggaataaa tccttggtca gatgttttaa cagaagaaaa
    97081 atacagagaa ctatttggat ataataaaca tacatttact ggtgtagatt atgttgatta
    97141 ttataagaat ttaatcaagg attgtggtgc agaggtagaa atagtatttg caaacaatcc
    97201 aaaaactatt cttaactata caacaagtat tttaacttgt gatatacata caagacaaag
    97261 aacaaagaga attttaagac aaaatggagc taaaaaagta tattcacttg atgatataat
    97321 gacagcaagt gtagatggta gtggttataa tgaccagtat ggacttttag gttcaaacaa
    97381 agctacagaa gaaacagtaa aattattccc tataaattgt gatgaagttg taaacaaaat
    97441 ccaaggtaat ataaaagaaa tcacagggaa agatgtagaa gtaatggttt atggagatgg
    97501 agcttttaaa gaccctgtag gtaaaatatg ggaattagct gacccagtag tatctcctgc
    97561 atatacaaaa ggattagaag gaactccaaa cgaagtaaaa ttaaaatact tagcagataa
    97621 tgattttgct gacttatctg gtgatgaatt gaaagaagca atttcaaaat acatagttga
    97681 aaaagataat aaatctgatg atttaacagg aaacatggtt tctcaaggta ctactccaag
    97741 aagattaaca gaccttatag gttctttagc agatttaaca tctggaagtg gagataaggg
    97801 tactcctatt atttacatac aaggatattt cgataactat acaaaatagt atgttttaat
    97861 aagatttaaa ttttttggat tatatatatt aacataaaaa tttattaaaa cctcttaata
    97921 gatatgactt ttcaagagtt atatctatta agaggtttat ttaatgttca cagataagat
    97981 atatttaaat aatttaaaca agattgtcag aaatttatat aatcttaaaa atttatataa
    98041 ctctaactct tatttatttc tgatttattt ctgaaataat atcactcttc aaaatttgtc
    98101 ttactggaat aattacagca actatactaa tagtgatatt taaaataatc atacctatgt
    98161 atagaggtgc atttatttta agaattggat ttatatataa atatacacgt tttaccataa
    98221 aataaatcat aaattgtcca ataacacttc caattaccat tataatactt gcatagaatc
    98281 catataaaaa cccttctctt atcatcataa gtgaaaactt attatctgta atacccatag
    98341 ctcttaaaat tccaaactca tgtcttcttg aaaaaattaa gtagcttact gtattgatta
    98401 tatggaataa acttattgca agaagtacaa atacaatacc atatataaat aagagttttt
    98461 gatttaagta ggtattattt ttttcaatag caatagtata atctgttacg atacatcttt
    98521 ttacatcact tacaacactt tttatgtcct cagacaattc cacactatta ctatcttctg
    98581 tcttttttat acttactgaa ttataatttt cgatattaaa gttatttttc atttgtccat
    98641 tcgtcataac tatatccata ccataatcac caatgaaata tatgttattt gccatcacac
    98701 gttttacagt agcagcaact acaaattctt ttgttgtata atcattctta ttttcttctt
    98761 taaatttaac aatttcacct gttggtttca ttatctttgg cactttaact tttattgtat
    98821 ctcctggatt tatatcaact gcatcataca tcccggttcc atccataggt agtctaacta
    98881 taaccttatt atttttaacc atatcatggg tattaatctc cccatctata atataagaat
    98941 ttaacccttc taacatgcca ttgttataac cataaatatt tgtttttaaa agatagccgc
    99001 cttcattttg ctttgtacaa ataccatcaa aaaaagtctt tatcctgtaa tctttttcaa
    99061 gaggtttaaa gaaatttttc caaaatagtt gttcttcttt aatttgcata gctccaaata
    99121 aatatcttac tggatagact tttgatattc cctcaatatt gtttaatctt gaaattttat
    99181 cttttggtat acctacatca aaatctgttg tttgcatagt tatttggtag tcagaattta
    99241 aaccatcatc agctttcatt gtaagttcat tattgttttt agtaagctgt atagagtaac
    99301 tagaacatag aaatataatt ccaccaagtg ataatgaaaa caaaattcca acaaataatc
    99361 cctttttttg agtcatgtat ttatgagata atacttttgt catgttagaa tgttttacac
    99421 tttctaatat tctctttttc gtattagtaa tcttaaagtt tttcatagat tctatactag
    99481 aatatttatt caactgatgt acaacacgta cagaaattaa aattaacaat aataagataa
    99541 ataaaaatcc taaataaata gatttttcac ttataaaaaa tgctcctgga acaatatcac
    99601 tactcaaaaa tatatgtgga aattgttcat atattgtaga cgctactcca atacctagga
    99661 agcaacctat aggaaatcca acaataaaaa gtaaaaataa ttctaaaaat agtagaaata
    99721 aaagttgttt attattagca cctaatactt ctaaaacccc atattgtgat attctctgaa
    99781 gtattgaaac atggaaaata ctatatactg ctgctgcacc aaacactcca acaagtaata
    99841 taattgcatt tgtatttaat tctaaatttt ttaagaactc aaatatatta tatttttcta
    99901 tattttttgg tggttttact ccaaattcaa ctgaaagagg ccagtttata taagcttttt
    99961 cttttgatat gttgaatttt ttcataaatt tataattttg ctttttaata tttttatttt
   100021 catcatattt tacataaact atataagaat ccttttcttt aggctttaaa taatcgttta
   100081 cgaatccctc catagcggtt tctgggtttg aaagacttga taaaatacca cataacttat
   100141 agattttccc atctaaattg atttctgttc caatttcttt gtttacattt aaattgttta
   100201 gagaatatgt gtcaagtact atctctccat ctttactagg aagagttcct tttaataatt
   100261 ttctacctgt catgtctaaa tatgaagaat cagcatttaa aaattctata ataaaaggtt
   100321 catctatctg atttttaggt tttgtaacac caagtctatc tacagtgtat ttctttgatt
   100381 ttttattttc tttaatttta ttaagttgtt ccttatctac tttatagaaa taatgataat
   100441 ctccactatc ttcccttatc ttttcaattc tacttttgtc tgcactatga actaaagaac
   100501 caattcccgt caataatgct actgatagta ctatgcttaa aactatagat atagattgtt
   100561 ttttataatg ctttatatat tgaattgaaa attttactag agacatcata gtacttcacc
   100621 accagtattc accacaactc catcttcaat atggataatt gagtcgcata cttgtgctat
   100681 attttcattg tgtgttacca taagtatcgt ttgatggaat tttgcactac tttcttttaa
   100741 taaacatacc acttccattg tagttttact atcgagattt cctgttggtt catctgctaa
   100801 tataagtgca ggtttatttg ctaaagctct agcaattgct accctctgtt gttgaccacc
   100861 agatagttcg cttggaaatt ttaaacgctt atcccaaatt cccaatgtct tcatcagcat
   100921 ctcaatatat tcatggtcta tatggtttcc tttatctaat gtaacaggaa gagctatatt
   100981 atcataagtg tttaatactg gcattaaact gtagttttga aatataaatc ctatatttct
   101041 tcttctaaat actgtcaaat ctttttttcc tattttagat atgttctttc ctttaattat
   101101 tacatcacct gaggttggac tatctaatcc acctataata tttaacaatg tgctttttcc
   101161 agaaccagaa gttccaacta tagcagtaaa tgtagctcgt tcaatttcta tacttactcc
   101221 gtttaaggct tttactttag tctcatcttt tccatagtgt tttactaaat tattcgtcac
   101281 taatatactc atttaatttc tcctttcaat agatatatgt tctataaaat attgtaagtg
   101341 acgataatta cactcatcct acaaagttag tttaaactct tacaattctg taagaagatg
   101401 ctaaaacaac atccacttcc tagtttagat tctactataa tgtttccatt ttctttttct
   101461 aaaattaatc ttgtaagata tagaccaatc cctgtgccat tttggtttgc cacattttta
   101521 cttctgtaaa atcttttaaa aatatcattt agttctctac tatcaatacc tattccttca
   101581 tctttaatag taatcttcgt atacagttcc atttttatta cagaaatagt aatcgtgcta
   101641 tctgatggtg agtattttat tgcattttct aaaacattta caattgcttc tatgatccac
   101701 tttttattat gaactaactt tatatctgaa aatggttcaa gatttaccct tatattttta
   101761 gcttctgctt tattaaagat agtactgata ctctgaataa gagtatcttt aattagtagt
   101821 tcttctactt caaattctat aactccatcc tctaatttgg tcattttaaa tagggattgt
   101881 aacaaccagt caatcttaaa agtttcattt ttcatctttt gtaaaaactc tttcttctgt
   101941 aatgtggaaa tatttatatt ctccagaagt tcacaataaa tggttatatt tgaaagtgga
   102001 gtttttaatt gatgtgacat atttgatatt aaacccttaa tcgcttcttt ttctaacttt
   102061 gactgttcta cctctatttc tatcatatcc ttaatttttt ttacttggtg agaaattttt
   102121 gacgctcttg tatccttcgt atctggataa gtaacttctt taccttccaa tatttgattt
   102181 aacattaaac ttaattcatc atatcttttt tgatttattt tagtagatac tataaatata
   102241 acaactgtac atattataaa ggctaatata aacatcttat tctacctcat tccataaata
   102301 acccattcca taagctgttt ttatatattt tggattagat gggtcatcct ctacttttac
   102361 tctaagtctt cttatattta cagacacaat attctcatca acataatttt cttcgctgtc
   102421 ccaaatatgg tgtaaaattt gttcctttaa taatatttga cctttatttt caattagata
   102481 acttagaagc ttatattcta cagagctaag ttccaaacat actttatttt tatatacttt
   102541 tagtagcttt tggtccaatt ttattccatt ggaatatatt actttattat tcgatttttt
   102601 tcttattgct actttgactc ttgcctttaa tacagataaa gaaaatggtt ttgtaatata
   102661 atcatcaagc cctatttcta atccttttac ttcatcaatt tctgagtctc ttgcagtaag
   102721 cattataatt ggtatatctg acttttccct tattagttga catacatcaa atccatctcc
   102781 atctggaaga ttgcagtcta agattataaa atctatattt ttactgttaa atatatttaa
   102841 tccttcttgt tttgtataag ccttaaatac attaaatcca tcattctcaa atgcataaaa
   102901 aagaccttca tttaagttta tatcatcttc aataattaat aagttcaatt ttactctcct
   102961 ttagattttt tagataaata attattttct tgcattgtca tactaaaaat attttgattt
   103021 tatttatatc actaaaaaga ttgtatctaa atttgttttc aaaataaaaa cattataatc
   103081 aagcatataa ttatatattc cccaatttaa ttacacttaa attgaaaata taacgttgtt
   103141 cttatataat taaattatac aacaataaag ttatattttt taaatatatt tttactaggg
   103201 ggaatagaat tgaaaagggt tgatgagaga aatactatgt ttgcaagagc aaattacaaa
   103261 aaagatagta ctgcttataa tgactattat aagaaaaatc ctgacaaaaa agaaattgat
   103321 gatagtataa gaaatagacc aaatttatgt agtgaaggaa caatgactta caatgagtta
   103381 aactctccaa tggcaagtag tgcattcgat tttttatctg atatcaaatc tttatgtgaa
   103441 ggaaaagttt ctgatactaa agtagatgta gatgcaaagt caatgacaaa aaaaataaag
   103501 ggtcttgcaa agcagtatgg agcttctgtc gttggtataa ctaaattaaa agactatcat
   103561 atttatacaa ataggggtag acatgaagaa aattacggtg aagaagttaa tctaactcat
   103621 aagtatgcaa ttgtatttgg atgtgagatg gataaagaaa tgataaatag agctccaatg
   103681 atatgtgaag ttatagaaac atcaaagtgc tatgtggatg catctatagt cggcatgatt
   103741 ttaagttact atataagaaa tttaggatat gatgctagaa atcatatgga tgctaattat
   103801 ttagtaatgc ctgtttttat agctcgtgat gctggtttag gagatatagg aagaaatgct
   103861 atacttacaa ataaagatta tggctctaga cttagattag gtgttgttac tacagatatt
   103921 cctcttttgg aagatgaata tgttgatttt ggactagaag atttttgtaa ggtctgtaaa
   103981 aaatgctctt ttaactgccc ttctcattca ctttctaatg atattaaaat tggtgatgat
   104041 ggaaaatata attgggtgat tgaacatgag acatgctata ttaaatggag atatttaggt
   104101 acagattgtg gtatgtgtat atctgcttgc ccatttagcc aaaacctcga aactataaag
   104161 aatactactt catttaaggg taataatgag cttattcaaa aagctttaga tgagtatact
   104221 tcaaaatttg gtaaaagaat atttatacct ggaaatccat cttggttgaa ataattttat
   104281 ttaataaaga atctgtctta gaatttatca taggacgggt tctttattaa atatataaac
   104341 ttttaaatac tttttctcgt ttataacaat tcagcaatgt ttttagtcta taattgacat
   104401 tataaaatat taaactaaaa ggagtaactg tatggaaaaa atattagtag tagaagatga
   104461 ttctatatta aataaaactc tatcatataa cctaattgaa gatggatata taattacttc
   104521 aaaatttaca gctaaatctg caatgaagtc tatttttgaa tgtgaatttg atttaataat
   104581 tttggatatt aatttgccag ataaaagtgg gtttgaatta tgtaatgaaa taaaggaaaa
   104641 ttacaatata ccaataattt ttttgactgc taatgatatg gaatgtgata tgattaaagg
   104701 ctatgaactt ggagctttgg attatataac aaaaccattt aatatcaatg tatttaaaca
   104761 gaaagttaaa gcttttttaa atcattttac aacaaaaaca aaacaagatt actataggga
   104821 tggatatctt gaaattaact tttctgagtt atctgccaat ataaatggaa atcaaattat
   104881 atttacacca ttagaatatc gtactttaaa actgcttact gaaaatccta aaaatatttt
   104941 aacaaggaaa gtacttttag aaaaactctg ggatatagat gctaactttg tagatgaaca
   105001 tactttaaca tctgttataa gtaggattag aagcaaaatt gaaaaagaca atcttcagta
   105061 tattaaaacg gtatatggca tgggatatat gtggttaggt gaaagaaatg aattttaaaa
   105121 aattttcttg tagttctatt tatttaataa ttgctattgg tataattttt acagctattt
   105181 tatttaatat ctcaatttat ataataactg atgatttaaa actagttact ctattattaa
   105241 tatatacaat agtactttgt ggatttatag cattaataat atttttactt cataaaaaaa
   105301 tagttatatt ttgttctaaa atatgtcaca ctttagatag tatgatgaat agtgaagaca
   105361 atattgaaat tgaattagaa gaagaaacta ttttatcacg tatcaatcac agattaatta
   105421 gaatgtatga agttattcaa gaaaatcgca atagtattgc tatagagaaa gctgatttac
   105481 aagaactagt ttctgatata tctcatcaaa ttaaaactcc tattgcaaat ttaaaaatga
   105541 ttaatactac tctactaaat caaacattta aaacagaaat tcaaaatgat tttttaatgg
   105601 atatggaaaa ccaattagat aaattagatt ttttaatgca atctatggta aaaacctcca
   105661 gactagagac aggtataatc acactatcta aaaagaaaaa ttcaatttat gaaacaattg
   105721 ctacagcact tagtggaatt ttgtttgatg ctgaaaaaaa gaatattgaa gttacagttg
   105781 attgtgaccc aaatttatat ataattcatg acaagaaatg gacttctgaa gctattttta
   105841 atatattaga taatgctgta aaatacacaa attctaatgg taagatacgt gtaactacag
   105901 aatgttgggt tatgtataca aaaatagata ttattgataa tggaaaagga atatcagaaa
   105961 gtcatcaagc agaaatcttt aaaagatttt atcgtgaaga agatgtacat gacatagaag
   106021 gtattggaat aggactctat ctttcaagaa aaattatatc tcttcaaggt ggctatatta
   106081 aagttacatc agagattgga aaagggtcga ctttttctat cttcttacct aataaataaa
   106141 tttttaaata tttcatttgt aatgattctg caacattttg gttttatact gtatttacaa
   106201 gatgttaagg aggtattatt atgagtattt tacaagtaat taatttaaag aaatattatg
   106261 gacaaaattc aaacattaca aaagctcttg atagtgtaac tctatatatt gaaaaaggcg
   106321 aatttatttc tattgtaggt acatctggga gtggcaaatc cacattgtta aatatgatgg
   106381 gaggattaga taatcctaca tctggaaagg ttattataaa gggtaaggag ttatcgacta
   106441 tgactgatga acagcttaca atctttagac gcagaaatat aggttttata tttcaaaatt
   106501 ataatcttgt tcctttactt aatgtatacg aaaatattat cttaccaata ggattggatg
   106561 gagagaccat agataaggat tttataaatg aaattataaa tatgctttct cttgaagaaa
   106621 aattatatga tatgccaagt aatctttccg gtggtcaaca gcaacgtgtt gctatagcta
   106681 gagcacttgt aacaaaacca gctattatac tagctgatga accaacaggt aaccttgata
   106741 gtagaactag ttcagatgta ctgagtttac ttaaagttac aagtaaaaaa ttcaaccaaa
   106801 caattgtaat gattacacac aataatgaaa ttgcacaact aactgataga attattcgta
   106861 ttgaagatgg aaaaattgtt aactaggagg tgtagtacat gtttagaaat aataatcgca
   106921 catttataag aaaaatagct ttaaatgatt taaaaattaa taagcttaaa acatatcttt
   106981 caggtatcat tataatgatt tctacatgtt tattattaac agtgacctta gtttcatata
   107041 atgcttccgt agacttagtt aatgcatctc catatcatgc tatatataaa tctgtagatg
   107101 aaaaaacaaa aaatatacta tatcaagata aaaactttag tagtgtagga gcttacaaat
   107161 taattggaag taataaaaag acagattgta ttatgtctat tgtttatgca gatgatacag
   107221 caattaaact tatgaatttt cagccattga aaggcaactt gcctacaaat aaaaatgaaa
   107281 ttgctatttc agaaaaatat ttacaggaat ttggtttaga taaagatatt ggagatagca
   107341 ttaaattaaa ttattatgat gatattacga ataaagaagt tcaatgtgat tttattatta
   107401 ttggatttct agaaaattat tatcaagata atgccaagca gtactataca gtcgtttcaa
   107461 atgattattt taagaatata gcttctacac ctttacaaaa taaaagtaat acttttgacg
   107521 agtcaatacc tgatactgta gatgtattag ttaaactatc agaagaaaat acagagaaag
   107581 attcagcttc aattaagaca cagttaaaga aaattgcttt atctttaggt attaagaaat
   107641 ataatatata cttaaatgat aactatattg aatcaaattt aattgatggt gagcagatta
   107701 ttacagtttt agtagttgga atagttgttc tcttttctag tgtttttgtt atatatagta
   107761 ttttttatat ttcagttgtt aattcagttc agatgtatgc taagttgaaa tcgttaggta
   107821 tgacttcttt tcagttaaaa aaaattattt ctctacaagg aaatattttg tcaattattt
   107881 ttattccatt aggggttata gcttcttgta taattgctta cataattcaa ccattggcat
   107941 ggcaaatgag ggctgattta tttataattt taattttatc actggtgatg tttttaactg
   108001 ttagaatttc tttatttaaa ccaactagaa ttatttctaa aatatctgct attgaagcca
   108061 tgcaatatac agaaactaaa tttagaaaaa aagtaaaaaa ttttagttat ataaatataa
   108121 aaaatctagc attaaagaat atcgagtcaa atagaaagaa aaatttgatt gcattaatat
   108181 cactaagcat tagtggagtt ttatttattt caatcgctaa tcttgctaat tcaatagatt
   108241 tcaaaaaaca actatctcaa caatttgtct ataacgaaga ttatataatt agcattaaga
   108301 gtgataactt atataagcat attacagaaa tccaacaaaa taatccacta acagattctc
   108361 ttaagaatga aattaaatct attcatggag taaaaaaatt aattgaatcc aaatcaatta
   108421 aaagcaatat tatagaacct tgcgtcaaag atagagatga aaaacaattt attactctaa
   108481 ttaaaggtat tacgcctgaa ctttcaaaat cacttgaaga atatattgta agtggaaaaa
   108541 tagactatac acatttagat tcagatagtt taattataaa taaatataga acaaaatcct
   108601 atagattaaa tttaaaagtt ggagatacag ttacatttaa tatttttagt ggaaatgata
   108661 ttattaaaaa gaaaatgaaa ataatgggaa ttattgacaa ttccaataca ggaggtatgt
   108721 tttttgcttc agacaaaact ttagaatctc taacaccata taatacaaat ttagattttt
   108781 ctattttaat agataaaaag cattctaaag aaattgaaga aaagttgtta agtataattc
   108841 agaaaaattc aaatttaatg ctttattcat atgaagatga ttatagaatg attactagag
   108901 catttcaata tataattata gcttcataca tttttgttgg tttaatttct tgctttggta
   108961 tactaaatat gaccaatacc ctaataaaca gcgttttaat tagaaaaaaa gagtttgcct
   109021 tacttcaagc cgttggaatg acaagaaagc aactgcaaaa tatgctttat agagaaggtc
   109081 taaacataag tatcaaagct atatgtattt caagtatact aggttatttt ggttcaaatc
   109141 tactttgcac ttttataaaa gatgtaatta gattagactt tattaatttt aaattttcta
   109201 tatttactat tttaattttt tcattcgtat taattggtat acaagtttta gtgactgaat
   109261 tacttgtaag aaatatagaa aaaaaatcac ttacagaacg cttacgttct cagtaagaat
   109321 gtatataaaa aatatccatt ttttatacaa gttttaacat aattttttaa aagctaaagg
   109381 gataggaaat tttgacttta cataattttc tgtccctcta cttgttttta ttttatacag
   109441 atatacttcc ttatatctcc aagcaacatc accagagaca taaacaagca tattacttat
   109501 tttctaaata tgtcaattgc atgacttgta acccctacta aatcttcacg ttcacaagta
   109561 gcaaggtgat attttaaata taacgcaaat gcatcatcat tcatagagtc tactgcttca
   109621 cgcatatata aagccaaacc atctgatgca acataatgca gtctagttac attaaataca
   109681 gacatcaaat catcaatgtt ttctttacgt acaagctcaa acaaatcctt tggctcagac
   109741 ttagcagcaa atgtctgtgg gtcaatcaaa cctttttcaa tgtattcaga tacattaata
   109801 tttcctctat ggaacccctc gtcaatgaga caaccatcag atataacata tgcaacaaaa
   109861 accacaccac caggttttgt tacacgaatt gcctcatgta aagcttgttg cttatcttct
   109921 ttgttataaa gatgatatag tggtcctaac agtaacgtaa tatcatattt attatctggg
   109981 aaaatagata aatccatagc attaccctga ataatgctta tattttcatt tgattgagta
   110041 tttttacgga aaacctctat attatgttcg accaattcca ctgcgtcaac atcatatccc
   110101 tgacgtgcca gtgtgtgaga atagcgacca gttgcagcgc caatttcaag cacacaatca
   110161 cctgatttta tgtacttatt aatgtaatgc atagtagtga gaaattccac cattccatgt
   110221 tttaatgcaa gtcgactatc ttcatcataa gtattataaa agtcaattaa gtattgtttt
   110281 gtttccataa tttcacctcc tctatattag ttaataaaca ttaaatagac aaattccaat
   110341 ctggtttttc ttgtcttata aaagctgtta atatattttt caacattttt tcagcactat
   110401 atctatctaa tgttaatttt tttgttgctg ttaagacagc catgccatga gtataaagaa
   110461 ataaatctaa aaatattact tttgcacatt ccaactctat tccaatgctt tccgaaaaaa
   110521 gtcttgcctt tttttcattg tcaatttctt tataaaaatc atttgcctct tccatcatca
   110581 aatctaaatc atttataaat aacaacttaa ataaatgagt ttcttcttga gcaaattcaa
   110641 tgtatgaaag cggaagcagt aaataaggac ttacactttt agaattacta taattaacaa
   110701 catacttatt atagtattca tatgcaaaag caagaaattc attttttaat tcattcatgt
   110761 tttcataaca agtaaaaatt ggtcgagtgg aacactgtaa tttacttgca atactcctcg
   110821 catttacagc ttcaaatccc acttctcttg taatatccaa gactgtattc aaaatcattt
   110881 cttttgttat ctttacttta ggtggcatat atgttcacct ctccattaaa tttttaataa
   110941 aatacatacg ttacataact atagtaacat atcaaagaat tatgtcaaga aaaatctttg
   111001 catttttttg caattcctaa aactgataaa taaaacatga gttgcaatta atctattaat
   111061 agataacagc aactcacatt ttcctttaaa tactcttctt tttatctaat atttcatata
   111121 cacaatcttc tattgaatta atatcttttt cttttctttt tttagaatca attaaaacga
   111181 aatacaatat aaaacctaca acaagtcccc atgttccgcc tttagcagca attacacctc
   111241 ccataagtcc aatcaatccc ttctctacac ctgtatcaca tagctccatt gatagctttg
   111301 tacataaata tccttgaact aaaagtgtta ctgacaacgc taatggtata agaggtgtag
   111361 caatctgcgc aattggataa aaacagataa aaattgctga aacccatact aatgtaccca
   111421 taccactaaa aatagactgc attgcttcct ttccaacctt gtacctttga gcaacacttc
   111481 ctgtaagtgt cgcagctaat ggaccgcaca ttggtatata tggagaaatg attgccataa
   111541 aaatatttct tatcccactt ataacattag acctatttga attgaaatct atatattcat
   111601 cttttctatt ttcactttca gaaagtacta aattttcacc tgttataaaa tcaccaaatg
   111661 caattatgta tatcatgaag gccattggta tcccttgtat aaataaaatt aagcttggaa
   111721 aacctattcc aaaaggagat actgtattta tcaaattttt aaaatctact atataaacta
   111781 aattatcaaa actaaatcta ggaatttcta tttctttact aaatataccc actattaaac
   111841 tcactaaaat agctgatact acaccatatt ctcctaaatg aaataaaaat ttattcttaa
   111901 cttttaaagt atcaagtctt tcagaaaaca ttacaaaaca agcaaccaaa attcctactg
   111961 ttatagatat gggataagag tcaaatctcc ctttaggact aaactctgat attatagtag
   112021 atataccaac acccattagt attccacctt taatagaatt tggtatctta ctaactaatt
   112081 ttccagctac accagttata cccattaaaa taaatatgat tcctaaatct atttgtaaag
   112141 ctgttaatgc ttgtattctt tcaataccca tactgaactt taacaaatat gcagttgtaa
   112201 gagttataga agctgtaatc cagccaggta caactgggtc tcccataaaa acatgcaagc
   112261 agtataatat tgaattaatt atagccatac tccatgctac ttcatatggt aatcctaaaa
   112321 tttgtgtact aagaccaatt gtgcctaaac ttgtcatact tgatattata ccttgaatag
   112381 cttctggttt ttcaaacctg taatgtataa atggaattct tatcttgaac attccaaatt
   112441 ttatatgagg ttgttccctt ctagcgagtt tttccataac ttcactccac ctttcaataa
   112501 ctcttataag tttacaactt tataattgtt tataaattat caatgtcgtt aaaattagta
   112561 tataacatgc aaattattta aacaataaat taaatttata aaattgatag attttgtgca
   112621 tatatagaaa tacctcttca tttttagtta tttaaatcac ttgataaagg ttttttataa
   112681 aattcaatag ttctattcca tgattcaaac tgtccttttg aatttccttc tacagttcca
   112741 cctgaagaaa aaatcccccc actcatactc atacataaag tcttctttag aggcataata
   112801 tatgaaattg gtaacggatg tcccatatta ttgtatgtta ataattctac gttattttgt
   112861 tttttctaat tttttttaac catataatat agaatcatta caaacttttt cttagttc
//
LOCUS       DAMKOJ010000003       107930 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.003, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000003 DAMKOJ010000000
VERSION     DAMKOJ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 107930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.003"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(243..656)
                     /locus_tag="PC592_000246"
     CDS             complement(243..656)
                     /locus_tag="PC592_000246"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDF4054271.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRV"
     gene            complement(697..1827)
                     /gene="rodA"
                     /locus_tag="PC592_000247"
     CDS             complement(697..1827)
                     /gene="rodA"
                     /locus_tag="PC592_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDF4054272.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNFLGRYYKALYIISLVLLAIVLLPGIGS
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVIVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQENFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(1911..2195)
                     /gene="minE"
                     /locus_tag="PC592_000248"
     CDS             complement(1911..2195)
                     /gene="minE"
                     /locus_tag="PC592_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDF4054273.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(2213..3010)
                     /gene="minD"
                     /locus_tag="PC592_000249"
     CDS             complement(2213..3010)
                     /gene="minD"
                     /locus_tag="PC592_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDF4054274.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(3034..3717)
                     /locus_tag="PC592_000250"
     CDS             complement(3034..3717)
                     /locus_tag="PC592_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDF4054275.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKVEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(3815..6793)
                     /locus_tag="PC592_000251"
     CDS             complement(3815..6793)
                     /locus_tag="PC592_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDF4054276.1"
                     /translation="MEENKQVDRLKIIKIVMSVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKNLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLN
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEDV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLAARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(6805..7293)
                     /gene="mreD"
                     /locus_tag="PC592_000252"
     CDS             complement(6805..7293)
                     /gene="mreD"
                     /locus_tag="PC592_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDF4054277.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGANALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFIKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(7308..8201)
                     /gene="mreC"
                     /locus_tag="PC592_000253"
     CDS             complement(7308..8201)
                     /gene="mreC"
                     /locus_tag="PC592_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDF4054278.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDIANFKDNSKKVKKLEEENEKLKKDMIS
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISTSVVSKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(8211..9221)
                     /locus_tag="PC592_000254"
     CDS             complement(8211..9221)
                     /locus_tag="PC592_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF4054279.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     VNMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(9342..10001)
                     /gene="radC"
                     /locus_tag="PC592_000255"
     CDS             complement(9342..10001)
                     /gene="radC"
                     /locus_tag="PC592_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDF4054280.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGDKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKATQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSVGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(10046..10630)
                     /gene="maf"
                     /locus_tag="PC592_000256"
     CDS             complement(10046..10630)
                     /gene="maf"
                     /locus_tag="PC592_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDF4054281.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLSDLLKKYFSINLFYGV"
     gene            complement(10850..11821)
                     /locus_tag="PC592_000257"
     CDS             complement(10850..11821)
                     /locus_tag="PC592_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HDF4054282.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     VAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(11837..12412)
                     /gene="rsxA"
                     /locus_tag="PC592_000258"
     CDS             complement(11837..12412)
                     /gene="rsxA"
                     /locus_tag="PC592_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDF4054283.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(12427..13020)
                     /locus_tag="PC592_000259"
     CDS             complement(12427..13020)
                     /locus_tag="PC592_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HDF4054284.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(13033..13602)
                     /locus_tag="PC592_000260"
     CDS             complement(13033..13602)
                     /locus_tag="PC592_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HDF4054285.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMDKSTYKDLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(13602..14579)
                     /locus_tag="PC592_000261"
     CDS             complement(13602..14579)
                     /locus_tag="PC592_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HDF4054286.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFAKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(14602..15939)
                     /gene="rsxC"
                     /locus_tag="PC592_000262"
     CDS             complement(14602..15939)
                     /gene="rsxC"
                     /locus_tag="PC592_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDF4054287.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKTIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTVTGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDVQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(16155..17099)
                     /locus_tag="PC592_000263"
     CDS             complement(16155..17099)
                     /locus_tag="PC592_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054288.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKNGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIDSISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(17210..18484)
                     /locus_tag="PC592_000264"
     CDS             complement(17210..18484)
                     /locus_tag="PC592_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF4054289.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSNPNNSTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGEVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGANNSSNSNSTNNSDKKPSSEESIEGKNGKVTSTVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKNNGWYKVKLSNGTTGWVSGSYISETNEGTKENSNSSSN
                     QNSQSNNNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(18616..18987)
                     /locus_tag="PC592_000265"
     CDS             complement(18616..18987)
                     /locus_tag="PC592_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF4054290.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(19214..19813)
                     /locus_tag="PC592_000266"
     CDS             complement(19214..19813)
                     /locus_tag="PC592_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054291.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(20014..20226)
                     /locus_tag="PC592_000267"
     CDS             complement(20014..20226)
                     /locus_tag="PC592_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDF4054292.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDSVSIEKLKEVIAELGFELKGIE"
     gene            complement(20299..22014)
                     /locus_tag="PC592_000268"
     CDS             complement(20299..22014)
                     /locus_tag="PC592_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4054293.1"
                     /translation="MKRIKVLTVVLAITLMVVGCSNSKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKDVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQSHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKALECLAKVEYANVNPVNQNDNKIKNQKKPAKKNLKKLTPEEEAKAKKAEE
                     DSIKKEAEEKQNREKEEVKKKLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKDYDLALVGWKLSSIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSSSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(22014..22568)
                     /locus_tag="PC592_000269"
     CDS             complement(22014..22568)
                     /locus_tag="PC592_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF4054294.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEQYNKIYGKKGKN"
     gene            complement(22561..23163)
                     /locus_tag="PC592_000270"
     CDS             complement(22561..23163)
                     /locus_tag="PC592_000270"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDF4054295.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNISIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKKLNNLTHPRIREKIISEIEELR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALNRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(23172..25820)
                     /gene="polA"
                     /locus_tag="PC592_000271"
     CDS             complement(23172..25820)
                     /gene="polA"
                     /locus_tag="PC592_000271"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDF4054296.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAEDDGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLLENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLESMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSNDTEQVEEKIEILKLKDIEKFIDEVNEKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITISEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNIDVHLDVDLNVGSSWYETK"
     gene            26139..26221
                     /locus_tag="PC592_000272"
     tRNA            26139..26221
                     /locus_tag="PC592_000272"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26173..26175,aa:Leu,seq:caa)
     gene            26912..28321
                     /locus_tag="PC592_000273"
     CDS             26912..28321
                     /locus_tag="PC592_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF4054297.1"
                     /translation="MIFSSLIFLFLFFPVTLICYYLANPKYKNVMLLLASIAFYTWGE
                     PKYIFLMILSIIVNYIFGIKVSGSKNKKMWVVLSVIYNISILAVFKYSNFFIDNINFL
                     FNTDITIPEVKLPLGISFFTFQIMSYVIDVYRNDAKVQRKLANLALYISLFPQLVAGP
                     IVRYQTVADSIEYREHNWDKFTQGVNRFVVGLGKKVILANQLGVIADGVFNKSAGDLS
                     RFEVWLGIVCYTLQIFYDFSGYSDMAIGLGKMFGFEFLENFNYPYISQTVSEFWRRWH
                     ISLGTWFKDYVYFPLGGNRVSKAKLYRNLFVVWFLTGMWHGTSWTFIILGLYYGILIS
                     VEKAFLEKFLYKMPRIVRHIYLLLIVMIGWVFFRVDDLPAAIKFIGIMFGAGNYPVIS
                     NAFNVFIIEYWYVIVGAILLSTPIVKVLKSLLIKKNKNTLNSTLYQVTNMVFIVSCMF
                     IVIIMLSSSTYNPFLYFRF"
     gene            28337..29530
                     /locus_tag="PC592_000274"
     CDS             28337..29530
                     /locus_tag="PC592_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054298.1"
                     /translation="MSKKKPRIVAISFLIIVFGFFILNFTLPKKKLSITENRNLAKFP
                     TVENLKKGDFIAKFEEYFNDHFAFRDRMISINTKAQASLNKTKVGNYYLGKDNWILGM
                     FPEILDQKQLSRYEKSINYLSNLSKDMGKNVYFTMMPHKTNMLKHLYPKYVDNMDNID
                     INLKNFKNRLNPDLIKYIDMDEYFLSNYSDKERENLYFKTDHHWTGYGAFEGFKMMAS
                     NMDLGLSKQDLDKHFSSYKKSIITDKKFIGSYNQNIDMLIKENEYVVYMTKDNQDYSF
                     DINGEEKEEKEVYATERDNKEWDYGGAYIRGAKTNILTIKNPKALVNKKILIFRDSYQ
                     APTTLLFADMFKEVEIADPRNINSIYKTYKEIIEESNADIVMFMYNSSGFDSMIDSMI
                     DKGIK"
     gene            29647..30027
                     /locus_tag="PC592_000275"
     CDS             29647..30027
                     /locus_tag="PC592_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054299.1"
                     /translation="MSKLNRKKDFYFVSLPHKTNMLKNLYPSGIKGKNNIDINKENLE
                     KQLKDINFLDIDDYFYKSFTEKERENFFLKTDHHGNSLGAFEEYKFILDKLDLSLSKS
                     EIDSHLKRYSTRYVNDCECSFIYV"
     gene            complement(30547..30990)
                     /locus_tag="PC592_000276"
     CDS             complement(30547..30990)
                     /locus_tag="PC592_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054300.1"
                     /translation="MKKNMLYLGIVYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERALDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(30993..31190)
                     /locus_tag="PC592_000277"
     CDS             complement(30993..31190)
                     /locus_tag="PC592_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054301.1"
                     /translation="MKNRLEEIRKERGIKQEELASVLQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDRSIEEIFIYEEE"
     gene            complement(31382..32248)
                     /locus_tag="PC592_000278"
     CDS             complement(31382..32248)
                     /locus_tag="PC592_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4054302.1"
                     /translation="MEWINKLNQAITYIEENLESGIDYAEAAKIACCSTFHFQRMFSY
                     IAEVPVSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNVEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPILEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYSNLPDIELYPNGDINSPDY
                     TTEVWIPIQKPS"
     gene            complement(32473..33342)
                     /locus_tag="PC592_000279"
     CDS             complement(32473..33342)
                     /locus_tag="PC592_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4054303.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDIRIMNRSEVFNNLEKVAGYKGNMIDSPSYIIILSDVKDNYIENSGYIGENIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGIDSDKEVTGIIAIGYGENVNNAKVLNATKTGQNYSK
                     SDMQVVTDKGSSRLGVEDVVYMNEWGNVASIEVLEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVILAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFELKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(33848..34069)
                     /locus_tag="PC592_000280"
     CDS             complement(33848..34069)
                     /locus_tag="PC592_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054304.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEEHEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(34570..35550)
                     /locus_tag="PC592_000281"
     CDS             complement(34570..35550)
                     /locus_tag="PC592_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054305.1"
                     /translation="MGDTSRFYESVRNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDILSWKQIVVLAECDGKNTTDDIINILSNRYRNIPNMREKVMEFFMFYENV
                     YLTFEDNIQTVSSVFEITGNKSYITPLYFTLEIDADNNTNNYFSEITSLLKCMYEKGC
                     RFIEVIGEDILKNKGMRDVFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSRNDDTRIKLKEDIKITSLIKRGHTVVRRDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSNGNVKSYSFQKDKRVYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(35714..36586)
                     /locus_tag="PC592_000282"
     CDS             complement(35714..36586)
                     /locus_tag="PC592_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF4054306.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPVEFDN
                     FKIVQVSDLHNKVFDKNNKVLMDKIKSLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINLENESVRIYKGNSHLNLYG
                     LIVPLECYPYFFANNKKLELSDNFVESNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRMPFVGGVLSPNREFFPKYDWGRYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKSKK"
     gene            complement(36750..37301)
                     /locus_tag="PC592_000283"
     CDS             complement(36750..37301)
                     /locus_tag="PC592_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4054307.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQQGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(37321..38223)
                     /locus_tag="PC592_000284"
     CDS             complement(37321..38223)
                     /locus_tag="PC592_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF4054308.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCISCNRCVDVCPQNISSLFDRTQINNKCDLCGECIKACLKDAICIMT
                     EEMSVEEIVKEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYNKGINIAIET
                     CGYFDWNKVNDVFDKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPEGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(38238..40610)
                     /locus_tag="PC592_000285"
     CDS             complement(38238..40610)
                     /locus_tag="PC592_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HDF4054309.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDERTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKVLVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISISENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSEQETDKKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDNAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLNQLAYLVKNSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMVKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(40831..41535)
                     /locus_tag="PC592_000286"
     CDS             complement(40831..41535)
                     /locus_tag="PC592_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054310.1"
                     /translation="MGGLCMKVKRNINKVAIVVALNLSLALMVGCKSPVSDKNLSSSK
                     QISKDSLKESVEDKKDESIELFNNYSQKMNDVKGREEVKKDLSQRFSKAIIDSGYSIT
                     NSKSDGSFVVSINSVEKPPEENIRSLFYSVSEDDKEGKVTIDILCAKEYPEDEKLSES
                     DKYIKFIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKIKQST
                     KVLKLSLLYKFDISNR"
     gene            complement(41761..43140)
                     /locus_tag="PC592_000287"
     CDS             complement(41761..43140)
                     /locus_tag="PC592_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4054311.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIVQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKIGYIKYSVFFYLFSVY
                     YECLDAVIYRILFFAITGNVISSKESLLIPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLANTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDKLRNNSKEIDEYVNSLKDEIKAFKYIYNTGNMILDIIINEKSEICLKKGIKFICS
                     INFSKVNFVKPIDVSSIFSNVLDNAIEACDKILDENINKYIRIKGTITKSFFVLKCEN
                     SKLNKITFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELSFENSMDKFILNIYIPL
                     DQDTDSWSD"
     gene            complement(43134..43847)
                     /gene="rgbR"
                     /locus_tag="PC592_000288"
     CDS             complement(43134..43847)
                     /gene="rgbR"
                     /locus_tag="PC592_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HDF4054312.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILEDINIEYEIQKYLSGEDLL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFITSLIDYVQEGYEVRAYRY
                     LLKPIELEDLKKHVLTCIKDIEINKKSHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLSKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTVILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(44094..44654)
                     /locus_tag="PC592_000289"
     CDS             complement(44094..44654)
                     /locus_tag="PC592_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HDF4054313.1"
                     /translation="MSVMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYRINKFGGI
                     FYFHKESPRKIKYTVDYYYDAENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGCGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(44750..45553)
                     /gene="zupT"
                     /locus_tag="PC592_000290"
     CDS             complement(44750..45553)
                     /gene="zupT"
                     /locus_tag="PC592_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDF4054314.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGGWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGVFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(45704..46867)
                     /locus_tag="PC592_000291"
     CDS             complement(45704..46867)
                     /locus_tag="PC592_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4054315.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     MGIPYVSAGGTGVIATIKGANSGKTVALRGDMDALQVVECTEVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKKIPGILERIAKS
                     TAGAYRAEAELEYGYLTPAVINDKECSKIATEAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(46927..48114)
                     /locus_tag="PC592_000292"
     CDS             complement(46927..48114)
                     /locus_tag="PC592_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054316.1"
                     /translation="MEAITAFCLVLISLTIGDVVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTAEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVMCLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIAGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(48477..50177)
                     /locus_tag="PC592_000293"
     CDS             complement(48477..50177)
                     /locus_tag="PC592_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054317.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIRDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPEGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(50417..50692)
                     /locus_tag="PC592_000294"
     CDS             complement(50417..50692)
                     /locus_tag="PC592_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054318.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEIEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(50811..51362)
                     /gene="mobB"
                     /locus_tag="PC592_000295"
     CDS             complement(50811..51362)
                     /gene="mobB"
                     /locus_tag="PC592_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDF4054319.1"
                     /translation="MKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGYRVGVIKH
                     TCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKDKSPLYKMIQLYEDMDLI
                     IIEGYKNYRFKRLEVTRKDKYEDIFSNKSDLVGIVSDIKYNLNIKQFDLNDYKNISKY
                     IESCIKNDILSISNVEIKNILKE"
     gene            complement(51367..52548)
                     /locus_tag="PC592_000296"
     CDS             complement(51367..52548)
                     /locus_tag="PC592_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDF4054320.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKRVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGEVFNRVLNKGEAVKIMTGGKIPRGANC
                     VIKKEDVTVIGDMITLNVKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVRDMLQNADFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVATLGEKLLFGLSGNPHAAIIVFDNVVVPVIEYLTYKKGIHYIKAIFKGEFNKLSN
                     KDRFVNGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDIVI
                     R"
     gene            complement(52760..53494)
                     /locus_tag="PC592_000297"
     CDS             complement(52760..53494)
                     /locus_tag="PC592_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054321.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINGNKVVNVETNSFSSQGIAVVDAESSIVIEKSDHEKSAVSLENFR
                     RIDLGEYVGVEESRITEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            53857..54762
                     /locus_tag="PC592_000298"
     CDS             53857..54762
                     /locus_tag="PC592_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4054322.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVNK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(54922..55764)
                     /locus_tag="PC592_000299"
     CDS             complement(54922..55764)
                     /locus_tag="PC592_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF4054323.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(55748..56506)
                     /locus_tag="PC592_000300"
     CDS             complement(55748..56506)
                     /locus_tag="PC592_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4054324.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHLADRYAEEGNIEGVERIQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(56523..56993)
                     /locus_tag="PC592_000301"
     CDS             complement(56523..56993)
                     /locus_tag="PC592_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054325.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDELLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDINMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(56993..57736)
                     /locus_tag="PC592_000302"
     CDS             complement(56993..57736)
                     /locus_tag="PC592_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HDF4054326.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEIAIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENNIEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLELGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(57740..58153)
                     /locus_tag="PC592_000303"
     CDS             complement(57740..58153)
                     /locus_tag="PC592_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4054327.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVKLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(58178..58930)
                     /locus_tag="PC592_000304"
     CDS             complement(58178..58930)
                     /locus_tag="PC592_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4054328.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(59170..60564)
                     /locus_tag="PC592_000305"
     CDS             complement(59170..60564)
                     /locus_tag="PC592_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF4054329.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENGYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAVPLALHGIVILNDGTKVEIS
                     IGEEDNDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLDDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(60584..60793)
                     /locus_tag="PC592_000306"
     CDS             complement(60584..60793)
                     /locus_tag="PC592_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDF4054330.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(60821..62266)
                     /locus_tag="PC592_000307"
     CDS             complement(60821..62266)
                     /locus_tag="PC592_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF4054331.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESMDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINEKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            62376..63170
                     /locus_tag="PC592_000308"
     CDS             62376..63170
                     /locus_tag="PC592_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF4054332.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQNKYKDKISIKKGIEFGVQTQLIDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLRQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            63220..64542
                     /locus_tag="PC592_000309"
     CDS             63220..64542
                     /locus_tag="PC592_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF4054333.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALTISIV
                     ASFNSSFLSIKFLKDAKLNLFILAVCPAIVIITISNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGVISG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKAIH"
     gene            complement(64642..65874)
                     /gene="cdeC"
                     /locus_tag="PC592_000310"
     CDS             complement(64642..65874)
                     /gene="cdeC"
                     /locus_tag="PC592_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HDF4054334.1"
                     /translation="MQDYKKNKRRMTNQPMPTMNEEEVYTEEINSEDMRGFKKSHHHN
                     ECNTDNKCDCHDDCKPCNPCKPNPCNPCKPNPCNPCKPNPCDDNCGCHDHCKCDCEPC
                     EMDSDECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGE
                     PLTFETEVVEVFGSVPSAGKASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGR
                     NCETTFEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALA
                     FPAVRAGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILK
                     LECNECCEPFYELIIPNDIDLVLCLQNTVSTLISEQIVVLASPNPIQPRLVDTFSKVC
                     DFSQCGPNHESGKPSCHR"
     gene            complement(66059..66239)
                     /gene="ssrS"
                     /locus_tag="PC592_000311"
     ncRNA           complement(66059..66239)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PC592_000311"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(66354..67265)
                     /locus_tag="PC592_000312"
     CDS             complement(66354..67265)
                     /locus_tag="PC592_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054335.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHSNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSKDERKILIKIESVL
                     DLVRGIKKLNNIDMVDIEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNEDEDNN
                     EGLNNEDEELDYEDKELDYDDEELTDEDEMEDNEDELVEDNKTDYENIENDEDIVYDE
                     ELYNINEQESEYNYNAKNTKTRTKKKR"
     gene            67477..67875
                     /locus_tag="PC592_000313"
     CDS             67477..67875
                     /locus_tag="PC592_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054336.1"
                     /translation="MKKLDAESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDTIMEKISDAETQRDTKPAKTKKTKPTKGKS
                     NSPAPKNTPTGQQKKSKGLFKKTKKSNPHE"
     gene            complement(67997..69013)
                     /gene="ccpA"
                     /locus_tag="PC592_000314"
     CDS             complement(67997..69013)
                     /gene="ccpA"
                     /locus_tag="PC592_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HDF4054337.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVSGF
                     NDVKIAKMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVI
                     ERKK"
     gene            complement(69266..69466)
                     /locus_tag="PC592_000315"
     CDS             complement(69266..69466)
                     /locus_tag="PC592_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054338.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSSGGFFDGEVGCGC"
     gene            complement(69500..69679)
                     /locus_tag="PC592_000316"
     CDS             complement(69500..69679)
                     /locus_tag="PC592_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054339.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(69861..70067)
                     /locus_tag="PC592_000317"
     CDS             complement(69861..70067)
                     /locus_tag="PC592_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054340.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(70115..70540)
                     /locus_tag="PC592_000318"
     CDS             complement(70115..70540)
                     /locus_tag="PC592_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054341.1"
                     /translation="MKYVGLLLTSIGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            70712..70939
                     /gene="acpP"
                     /locus_tag="PC592_000319"
     CDS             70712..70939
                     /gene="acpP"
                     /locus_tag="PC592_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF4054342.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(71080..72084)
                     /locus_tag="PC592_000320"
     CDS             complement(71080..72084)
                     /locus_tag="PC592_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF4054343.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVPNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(72098..73000)
                     /locus_tag="PC592_000321"
     CDS             complement(72098..73000)
                     /locus_tag="PC592_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF4054344.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKINEEKANFEPQDLNLQIIYDDFDIIMVNKLPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGCVDEELINRQALHAYRLEFEQP
                     RTKEKLKFKADIPEDIKELISKLR"
     gene            complement(73197..74372)
                     /locus_tag="PC592_000322"
     CDS             complement(73197..74372)
                     /locus_tag="PC592_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF4054345.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTSLIVKR"
     gene            complement(74460..75305)
                     /locus_tag="PC592_000323"
     CDS             complement(74460..75305)
                     /locus_tag="PC592_000323"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HDF4054346.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(75403..76200)
                     /locus_tag="PC592_000324"
     CDS             complement(75403..76200)
                     /locus_tag="PC592_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF4054347.1"
                     /translation="MSTSDVKVYENVAVEVNGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPEILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(76219..77229)
                     /locus_tag="PC592_000325"
     CDS             complement(76219..77229)
                     /locus_tag="PC592_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF4054348.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVEVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(77248..78030)
                     /locus_tag="PC592_000326"
     CDS             complement(77248..78030)
                     /locus_tag="PC592_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF4054349.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(78089..79225)
                     /locus_tag="PC592_000327"
     CDS             complement(78089..79225)
                     /locus_tag="PC592_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDF4054350.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(79933..80400)
                     /locus_tag="PC592_000328"
     CDS             complement(79933..80400)
                     /locus_tag="PC592_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HDF4054351.1"
                     /translation="MSISNVREYFKQFGKDDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLIPEEVLEFTGHAIGGVCPFG
                     LKNSLKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(80479..81021)
                     /locus_tag="PC592_000329"
     CDS             complement(80479..81021)
                     /locus_tag="PC592_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054352.1"
                     /translation="MKKFIKVSFFIFGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDIGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGINKCSSYVNIDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYVVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(81073..81759)
                     /locus_tag="PC592_000330"
     CDS             complement(81073..81759)
                     /locus_tag="PC592_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF4054353.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLMSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGLIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDMANAKYINLYSMTFLTIIIFIISMYFSI
                     RISKKNKFNY"
     gene            complement(81759..82619)
                     /locus_tag="PC592_000331"
     CDS             complement(81759..82619)
                     /locus_tag="PC592_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054354.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     EFDRERFDEYLNKFDIEENMHIKNLSKGQSEKLMLSSALSHNAKLLILDEPTTGIDPI
                     VRSEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            82753..83553
                     /locus_tag="PC592_000332"
     CDS             82753..83553
                     /locus_tag="PC592_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HDF4054355.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            83578..84147
                     /gene="yfcE"
                     /locus_tag="PC592_000333"
     CDS             83578..84147
                     /gene="yfcE"
                     /locus_tag="PC592_000333"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDF4054356.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YTESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(84405..85457)
                     /locus_tag="PC592_000334"
     CDS             complement(84405..85457)
                     /locus_tag="PC592_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HDF4054357.1"
                     /translation="MKIKSRKIIAFVLSLGIMMPSCVYADTISKNQNTEVDMNNYLQG
                     RKSPKEETLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKEFLEDMGVLVSRIGGADREE
                     TSLLLTKQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTETYIVGGEYSISKKLEGQLVNAERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(85664..86890)
                     /gene="pepT"
                     /locus_tag="PC592_000335"
     CDS             complement(85664..86890)
                     /gene="pepT"
                     /locus_tag="PC592_000335"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDF4054358.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEELNVITYVKDSPELVEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFNVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIATEISEMFPADERPETTEGYEGFWHLNSIDGNVENVS
                     MSYIIRDHCREKFEYRKSIMVENIEQINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELNIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            complement(86983..88035)
                     /gene="ytvI"
                     /locus_tag="PC592_000336"
     CDS             complement(86983..88035)
                     /gene="ytvI"
                     /locus_tag="PC592_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF4054359.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGGI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSVKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDIEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            complement(88183..89436)
                     /locus_tag="PC592_000337"
     CDS             complement(88183..89436)
                     /locus_tag="PC592_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF4054360.1"
                     /translation="MLESPDNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            complement(89567..93094)
                     /locus_tag="PC592_000338"
     CDS             complement(89567..93094)
                     /locus_tag="PC592_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4054361.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNLQLQSLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQNSYEESKTVYEEQLKLEKNELRKNELDLKNGEIKEKI
                     ALVENDSNAKKVDPYIGSVQNLEKKIDEDSFTVSNLEKKLVILNQELEVIKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDKELKELKESGINLNKTKVELEKVKQMS
                     ESRKDAVTKSIKEVEGKINKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKINKLEEI
                     LKETEDINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KADNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEQLK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKLSGYLSIEKMKTKELEDVKGKLGDIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYIGLKTITKVSNLLSKVKEIRENEKELELLSIGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYLEKKLSRDNKYKEVINITKGDLAKNLLHSVEEDICKILEQEESSKK
                     KLEQQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     ADEVKKLIEEILEHEEEQKLLAFKIKSSKEKLNGRSVKKESFEQLKDEIYNLKVEIGN
                     ISKNIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            complement(93081..94292)
                     /gene="sbcD"
                     /locus_tag="PC592_000339"
     CDS             complement(93081..94292)
                     /gene="sbcD"
                     /locus_tag="PC592_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HDF4054362.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITCATQGCTKLNINGENVVVATLPYPSEKRLNEVFSSE
                     DDFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDKEIWSYFEINTEEVISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            complement(94336..98163)
                     /gene="addA"
                     /locus_tag="PC592_000340"
     CDS             complement(94336..98163)
                     /gene="addA"
                     /locus_tag="PC592_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDF4054363.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRISLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSAEYKKIVDISQACNKSWDETYKK
                     MSSMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISNIVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNEFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFEMDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRTNNKESEIEEEEK
                     LDNIQLEARMVGKIIKDLMKVNEEGKLQKVYDKGIGGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYNEFKDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGVENSDTISQYEILKGKNFLDWIMPCVLKHRDLSN
                     LLDEVGLDAVFSVEHNSKWYGKLWDKNDILVEKKNNEEKESIEKILEKIDVDSPDSDY
                     YNEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEERDKISGAERGTIVHLVMEVLDLKNVSNVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFESNIGKRMLNAELINREKSIYAQVNMKDIYIYEKLINNDDKKLYDEESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            complement(98163..101630)
                     /gene="addB"
                     /locus_tag="PC592_000341"
     CDS             complement(98163..101630)
                     /gene="addB"
                     /locus_tag="PC592_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDF4054364.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRMLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQAGFVSSITEMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDVNYTGYSKADMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSKQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     EKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINVLENYVLANGIKGKKWFDEKWDYRITQSLSGE
                     ESEFELELKDKINEIKNRVLEPIVTLQEKLKGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSQTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDEDILKKITVKSPTFNELINVIKNYDSDGYNKEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHRIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKARKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLSWRGIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKIVLENGQEVSLIGQIDRVDEFEEGENKYIRIVDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDKDININPAAILYCRINNPIAKFNEDKDDVEIQEAILKELRMKG
                     LVVKDSHIVKKMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVKH
                     AIKDLCEDMLSGEICIAPYKHKDGTSCDFCDYSAICQFDSTMKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            complement(101620..102450)
                     /locus_tag="PC592_000342"
     CDS             complement(101620..102450)
                     /locus_tag="PC592_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDF4054365.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDNKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMSLNGDTIQAKYDLVVIGNNNIDIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYNEEKHETNRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            complement(102559..104778)
                     /locus_tag="PC592_000343"
     CDS             complement(102559..104778)
                     /locus_tag="PC592_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF4054366.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILVLTYMNSAVNNFKGRIRKILEEHKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKNIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGQKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENRNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVEYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINIKWYDSWKFEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLVFEELGPNSLSKRRVINNIASIIDFILHCDD
                     IEKLIVVLDKVFIDTDNEEELKYFLEKLKNYSTEEIIYDFEFSKLDNDLIEFNEESDI
                     YLNFKRGINIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLASENI
                     NMDLEDVYNLLFDVKNKVFNHIIDVVYEINGYEPEPGSITICNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLGRLNRHIIKKRSN"
     gene            complement(104771..106684)
                     /locus_tag="PC592_000344"
     CDS             complement(104771..106684)
                     /locus_tag="PC592_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054367.1"
                     /translation="MEYLIDKSSLKECGNEPLDKYREILDKTKNNSRSILLLVPNNNT
                     KIQYERSLRLNYSEELKITTYISFVKKELLKYWPLIIENCDEINKKAVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIAKSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNSLSVYLYNQYLLNDDFYVKSLFKEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDMDYINEKIISKIK
                     SKEENIKRKEIGIEDLYLLPATIKLNQSSQLYNEMLDLISEKIISLIEEGVSLRDIAI
                     ISPINNSILEYQIRDSLIEKNIDVFNIKKDKKAVDYPYGNALVVATCMFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNMDEHSQYRDILQYIEEKKKSDLKIHE
                     FLIQFYIDKMLSLKDGKKNVGLCKKIIAESESFSESLSLLGMKKEEIFIEALKTAIND
                     YYSVVDIEELKSKDKIVITTPYSYIASNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAYKSEYAINGYIQESILYSI
                     LLKISHKGDENYD"
     gene            complement(106916..107875)
                     /locus_tag="PC592_000345"
     CDS             complement(106916..107875)
                     /locus_tag="PC592_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4054368.1"
                     /translation="MISTNVINKVNGITKDNVTNNRVYGADRHETNANVIKKFYTDDE
                     LEAILVAKSDVLVDALAAGPLAASLKSPILITPKTYVSAYHKTNLETKSANKVYKIGG
                     GLTSKVMSSIASSLSKHNTTPADPGSNNGAKTVMIDPGHGGSAPGNSFGGMIEKDYNL
                     NTSLATTEYLRSKDINVIMTRDTDKTLSLGSRTALSNSLKPDLFTSIHYNGDNNRKGH
                     GVEVFYKFKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRTN
                     NIPAVLVECAFLDNEKDVSLINSPAKVKEMGIQIGKGIEDSLK"
BASE COUNT        34189 a        19356 c        11299 g        43086 t
ORIGIN      
        1 atataagttt aaatatatat aataatagac ttaattatat ttcatattat taaaatagag
       61 taatagttta aattctacta ctctatctat aatctatttc ttaattattc aatctcaaat
      121 ttagctcctc atcatttaaa tctttcataa gatttctaaa ggtactaggt ttgttgcaaa
      181 agaaagacta tggcattaaa cacttatata tctgtttctt taaactgtaa tattaatatt
      241 ttttaaacac gctgactttt gctttttcta acttctctcc atgatagctc tcccctatca
      301 agagctttta taaatatttc tgctgaagct aaatttgtag ctattggaac atgataaaca
      361 tcacaaagtc ttattaaagc ttgtatatct gtttcatgag cctgagatgt caatgggtct
      421 cttaaaaaaa taactaaatc tatttcttgt gttactatta aagaacctat ttgttggtct
      481 ccacctaaag gaccagatgc taatctgttt atatttaatt cagtttcatc catgattctt
      541 tttcctgtag ttccagttgc atatagtcca tactttttta aaattgattc ataacctata
      601 caaaatccga ccatagtatt tttcatttgg tcatgtgcta ccaatgctat attcatatat
      661 ctaatctcct caatttatgt ttagatgtat ttaaatttag aaatttattt tctttcttct
      721 catacacaca tttagtacta accctaagtt cgctaaagat gtcaataacg aactacctcc
      781 ataacttaca aaaggtaatg ttactccagt tactggtatt aacgcaaccg tcatacctat
      841 attttggatt atctggtaac caaacattcc cataacacca accacgatga gggttccata
      901 aaagtctttt gcatctcttg caattgctaa aagccttaat aggaatatca taaataagat
      961 tatcaacact gccattccta ttacaccaag ttcttcacct acaacagcaa atataaagtc
     1021 actatcttgt acaggtaaaa agttttcttg attttgactt ccattgtaaa gtcctttacc
     1081 agttacacca ccagaaccaa ttgcaatcag agattgcata acttgatagt ttccttttag
     1141 tgttacatct tctgggttta gaaaagcttc tattcttacc ttttgatggt ctgccatcat
     1201 taaatacatc agtggcattg acaccaatag tatgattatt cctcttttta tcaactttga
     1261 actaagacct gctgtaaaca gcattgcaaa tatcatacaa caaaatacaa ttcctgttcc
     1321 caagtctggc tgtgcaatca ataatccaat aaatggaaga gaataaacta taacaggcat
     1381 aacttccttt aatgtattta atttatcctt tttggattca agtatttttg cataacttag
     1441 tacaaatgtt aatttgacta tttcagatgt ctgcaagtca agtggtccta aattaatcca
     1501 cgacctagct ccacctttta ctgacccaat tccaggtaat aaaacgatgg ctaacaaaac
     1561 aagacttatt atataaagag ctttgtaata cctgcctaga aaattataat caaaaaataa
     1621 tatgactata atcattccta tcccaagtac aaaggctaac ccttgtttaa tcaattgatt
     1681 atatgaacct gttgaattag catgtgttgc actactaagt atgacaagtc caaaaataaa
     1741 gatagctaat actgtaacta taagtttcca gtctaactgt tttatcaact taattgtcga
     1801 cttataatta atattgattt ttttcaaaga atcaccgtct ttctatcttt aaacatataa
     1861 ttaataaaag gggcatatac caataaggat atcccccttt taagcactaa ttacatacat
     1921 ctatctttta tattctttag tggtatatta gcaactaatg cagatacagg tttgtcatca
     1981 tgctcacctc tgcatttaga catttttatt tcaaggccat catcttctat ttctgcataa
     2041 ttagctatta cttttaaaat gtctgttttt atcatctcta aaagttgtgg tgaacaatct
     2101 actctatcat gaactaaaac tagctttaat ctctctttag caacagactt actagtttta
     2161 gcttcgttag aaaaaactct aaataaatct aacacagatg tatcctcctt tgctacttag
     2221 ccatgctaaa cattttttta agtctaccaa agaatccatc ttcaacttca agatcaagta
     2281 gaggaacttc ttcatttagt atcctttttg cgatattttt gtatgcttga ccagcaagtg
     2341 acttagaatc aagtatagct ggctctcctt tatttgttga tataattata ctttcatcat
     2401 caggaacaag acctaacaaa tctattgcta atatttctat tatatcttgt ttatccatca
     2461 tgtctccacg cttaaccata tcatttctaa ttctatttat aaccaatctt atctctttta
     2521 tttcatttgc ttctaataga cctattattc tatcagcatc tcttactgct gatatttctg
     2581 gattagtaac tacaatagct ctatctgctc cagctactgc atttttaaaa ccttgctcaa
     2641 tacctgctgg acagtctatt attatatatt cgaaagattc ttttagtttc tcacacaggt
     2701 caatcatctg ttcaactgag acagcatttt tatctctagt ttgtgctgct ggtaataaat
     2761 atagattatc aaatcttttg tcttttatta gagcttgctt aagcctacaa gttccttcaa
     2821 ctacatctac tatgtcataa actattcgat tttcaagacc cattactaca tctaagtttc
     2881 taagtccgat atctgcatcc actactactg tttttttatt ttctaggctt agcgcagttc
     2941 ctaagtttgc tgcggtagta gtttttccaa ccccaccttt accagatgtt ataactataa
     3001 cttcgctcat aatactaccc cctatttttc tttctatttg tctaactttg acaaatagct
     3061 ttcgattaca attcttccat tacttacaaa ggctatttct gggctaattt ctgattcact
     3121 ttcataattt tcttcatcat ctggagcttc tgcaatatta tctgctattt gtaatatttt
     3181 aggattaaga tttccagcaa caacatatgc aaattcatta ccttctgcac ctgcatgtac
     3241 aaaaccttct attttgccca ttacaaaaac attacctcct gctacaacct tagcaccagc
     3301 atttatatct cccataacaa ctgtatttga ttttgaaagg acctttgaac caggtttcat
     3361 atcattcaat ataactacat caccttcaaa ttcaatattt tcaccagatc ttagggtatt
     3421 gacatatttt gttggaaaat tactattttc ttcaactttt tgatcttcaa caaattccac
     3481 atcaaatcta gaagtaattc cttctttcag ttctagaatt tccatgtcag ttaaacaatc
     3541 actgttaatt ttactaattt tagccccatt aaaaaagcca acatatgctt ccaatttgtt
     3601 tattattttt tcctgtattt cctcaaatgg agcttctctt tttatattta ctattatccc
     3661 tcttttatta cccttgaact ctactagttc ttgactacaa atttctctta aagacataac
     3721 aacctccaga gtgatatatc atttatattc ttcaaatacg ctttaaaccc ttttattttt
     3781 tctatataaa gctaaagttt atacatggat tgagctatct attaatttgt gactcgaaat
     3841 ttatattttc gtcagaagaa ttgttaacat cattcgtctt gttgtcattt ttactattag
     3901 ttggctctaa tcccatataa gttccaataa cttctctagt tggtaaaagt gagaatacac
     3961 ttgaatcacc ttgaggaatt acacatacaa cagctatttc tgggtcatct gctggagcaa
     4021 aagcaacagt ccatgtaaaa gaaccataat cttgcttaaa tctatctatt tggtcatctg
     4081 ttattttggg atttaattct tttatagctt ttcttagata tgaagaattt accttatcgg
     4141 tgtcctctaa tctaactttt actccatctt ctaattcttc ctctaatttt tttctttctt
     4201 cgtctttcaa atctttattt tctaatttct tttttatttc cttttcctta gctaaagaaa
     4261 gctctttttc tttttctgct ttcatcttat cagctagttt aattgcatca tttaggttaa
     4321 cattataaga tgacatatga ctttttaaat attcatactc attatctgta ggtattttcc
     4381 cactcttctc agctgtacca gtttttgctg ctacatctat tgggaaatca gcaaaggcac
     4441 tcttagctgt accttgtctt gcagccaatt tcataccttt tgttaattct tttaagttat
     4501 ctggattttt aaaaggtatt ttttctactt tcttctggtc attaatttta actgatgaat
     4561 agtcacttga aacagctcta tcaactacag ataattctac tagattacct ccatttgcta
     4621 tggcagctac atatcttgat atttgagctg gtgtataagc attttcacct tgacctatag
     4681 ctaagttgaa tgtatctgca gtactccatt ttgcaaagtt aaaataactg aatactgcta
     4741 aatctgctac atcttctatt ctatcttctt taacattcat tttctttagc ctattcattg
     4801 tttcaactct accaggagtt ttcttttctg ctgcccaact tacaatctca ttaattcttt
     4861 tctcatattc tttaggattt ttttctctag ttatatcaac aaaatcattt gccatttctc
     4921 tttctaaatt cgactttaga agagcttgtg ttgatttcaa tttatcttct gtgctaggaa
     4981 ctttacctgc tctttcttct acttcatctt gaagacctgt attttgatca agtccaaata
     5041 attttgcata ctcaagtatt ttatttgcat tcatatctat accaatgctt tttccatctg
     5101 gccatgtttt acctgtacca attgttgcca tatatatatt acaagactct tgtattgctt
     5161 tatataagtt tgtcatacca tggtttcctc taccatggtt ccatacatag tcaccaaaag
     5221 attttttacc taacattata accccagggt catttatagt aaagtttgga ttcaaaccat
     5281 tctctaacgc tgccattgaa gttaccatct taaatgaaga acccggctga aattcccctt
     5341 gtgtaaccaa gtttaaaagt ggacttcctg ctagtaagtc atttggattt tttggttgaa
     5401 gtgctttata atcttctgta gaaattcctt ttgcaaattt atttgggtca taattaggat
     5461 aacttgatga agctaatact tctccatttt taacatcaat agctataaga gctgctgatt
     5521 gtgcttttcc tgcatatgca ctaattggtt tgtccccaaa tttactttta aaggtaccac
     5581 ccttagaagc aacttcgatt atctgtttta atgcattatc tgaaacttct tgtaaatctt
     5641 tatctagtgt aagatataca gtatctcctg atttaggttt tttagactca atttctttac
     5701 tgattctacc cagtgcatca actttaacca ttttataacc atcagttcct cttaatctac
     5761 tttcattact cttctctact cctgcaagac ctaccatatc tccagtttca tacccctttt
     5821 gaaggtatga ttctatttga gtggatggca tttttcctac atatcctaac atatgagaag
     5881 ctaatgaccc attaggataa tatcttactg gttctactgc tattgaaaca ccaacaaggt
     5941 ccatagcact ctcttcaatt tgagcaattg tagtttctcc tacatccttc gcaatagtta
     6001 ctggattata ttgagagtat ccttttgatt ttatcaaatc tcttacaacc attatttttc
     6061 ttgcatcttc atcacttaag tttttatcaa tttctaatgc atcactattt cttacttttt
     6121 caaacgcttc tttggcactt agtttagttt cttttatctt ataactagcc aaccaatctc
     6181 tcttatctct ttctgctgtg aacatccatt tactaactaa aataggtgga taatatccat
     6241 tttcatttag ttttgcctgt aatcttgtcg catccaatct tttatcttct tgagataata
     6301 ttccagctga tataagttta tctaccaagt aataaaaact ttccttagca ttataatcat
     6361 ttggaatacc attttctgac ttatattccc taatatctct gtcatatgta taatagtact
     6421 ttccattttc tacatatata ggaaactcat ctacatattc ttcaccattt ctctccagca
     6481 aatttataag ttttaatgat atttcatttg ctcttgaatg cttatttgca tcttttttat
     6541 taatatcgtt acctgaaact tgaacagtaa ataagttttt atttcctgcc aacagtcttc
     6601 catatctatc ttttatttct cctcttggag cttctattgc caacttttta tatgttttat
     6661 tctcagctaa ctcattgtaa tattcatatt taaatgtagt catatagatt atttttacta
     6721 aaatagctaa aaatatcacg ctcatgacta tcttaattat ttttagtcta tcaacttgtt
     6781 tattttcttc catgaaatca ccaactaatc ttctttaagt tttaaaactg ctcttttaga
     6841 taagcgatat attactaaac caattaaact attcactatt ggtgctacta gtaaaccttt
     6901 tataaaaagt gttgatatat tgtagctttg ataaattata ctagatgtac ctatattgac
     6961 aattgaatca attaaactgc ctataaaaat taaaacgaaa gtaataatat aactaccttt
     7021 atatagctga tctctcatgt acccaattgc atatgcaata ataaacaaaa ttaatgcatt
     7081 tgcaccaaaa attccaccaa cggttatgtc tttaataagc cctattattg ctgctataat
     7141 cccaccttct aattcatcca aataaagaga gattatggtt acatatataa gaactaaatt
     7201 aaagcttatg ccaaaaatat ctatataatt tgttatacta ttttctatag tcataagcac
     7261 aatccccaac agacaaagta aaactttttt cattgttttt atccccttta tcctatattt
     7321 cttggttcta tgactacaac gtcatttata ttcttaaaat caacataagg ttttacaact
     7381 acatatttta atgacttatc tttatcatca accacttttt caacttcgcc aattggtata
     7441 ccatctggga agaatccaag acctgatgtt gttattatat ctccttgaat tacattatat
     7501 gatgagtcaa acatatatcc ttgcaaatat cctttactat tataactatc tttattatct
     7561 aaagtagtat tttgagtaat tgtaccttta gcattggcat cctttgctag tttaaagctt
     7621 acagatgcct tagaatccaa tagtgaaatt gccttactat aattgttgga aacttcataa
     7681 actatgccaa ctaacccact accattcata actatacttt ctttttttac acctgaattt
     7741 tttcctgcac ctatgacaaa actctcatac cagtttccat catttttact aacaacactt
     7801 gttgaaatac ttgtcgcctt atactcttct tgtacaaagt taagtgtctt ttttaactct
     7861 tctagcgatt ctgttttatc tagtttggca tttaaagata tcatatcttt tttaagtttt
     7921 tcattttctt cttctaattt ttttaccttt ttagaattat ctttaaaatt tgctatgtct
     7981 ttaaaaccat ttttgataaa agaaaatcca tcatttattc ctttacctac acttgtaata
     8041 gcatctgaag ctactcctaa atttactggg ctaccactag aaaatttacc aattgatata
     8101 cccacaattc caattaaagt gatagcaact acgcccgttg ctatcacttt aacattaatc
     8161 ctttttttct catttttgtt cttgtcaaat ctcaaggcca tcaccaactt ctaattctta
     8221 gtattcatca ttaatacttt ttcaaagatt tcttggtctt caacagattt tcctgttcca
     8281 agtgcaacac aatcaagagg tgtttctgct atttgtacag acataccagt ttcttgtgta
     8341 ataagcttat caagacctct aagcaaagct cctcctcctg ttagcattat tccgttttcc
     8401 attatatctg atgctaattc tggtggagtt ctttctagtg tagattttat tgcatctact
     8461 attgaactta caggttcttt taatgcttct ctaacttctg tagagcatat ttctattgtt
     8521 ttaggtaatc ctgagattaa atctctacct cttatttgca tatttacttc ttcatcatct
     8581 ttaaatgtag agcctatgtt aatttttaca ttttcagcag ttctttcacc tatcataagg
     8641 ttatattctt tttttacata agccactata gactcatcaa attcgtctcc acctattctt
     8701 atagatttag cagtaacgat tcctcctaaa gatattacag ctatttctga agtacctcca
     8761 ccaatatcaa ctaccatatt accttctggt tcttcaactt ttaatccagc ccctatagcc
     8821 gctgccattg gctcttctat aaggaatgca tctttagctc ctgcttgtct tgcagcctct
     8881 tctatagctc tcttttctac ttctgtaact ccaaaaggaa cacatatagc tattcttgga
     8941 cttacaacac cttttttatc agccgctttt tgtataaaat aactaatcat tgattgagtt
     9001 atgtcaaaat cagctattac cccatctttc ataggtctta tagctactat atttcctggt
     9061 gttctaccta tcattttttt ggcttcttca cctactgcta atacctcttt actgtcatct
     9121 cttattgcga caactgatgg ttctctaaca acaatacctt gtccttttat gtaaactaat
     9181 gtatttgcag tccctaaatc tattcccata tcctttgtca tcttattaaa actaaaaaaa
     9241 cctttttttt ctttcttttt ttccttagcc atgattttac tccttcctac tattaagaat
     9301 catgtttaaa acattctctt cttattttat cacatataaa gttaaattat catattttct
     9361 ttaaagctaa agtataatcc atctccaata attatatggt ctattatttc tattccaatt
     9421 atttctccac atttaataag tcttgatgtg atatttttat cttctcttga tggttccaca
     9481 cttcctgaag ggtgattatg cattactatt atcttacttg cacttcttct tatagcttct
     9541 ttaaaaacct ctctaggatg gactaatgac gagcttaaag tccctacaga tacatctaca
     9601 tcagatatta tctcattttt tgtgtttaaa agaaccgctt taaaaacctc tttttttaaa
     9661 taccttaggc tatccatata atatctctgt atatcccaag ggttccttat tttatacttt
     9721 ataggtttaa aactagctac tctagagcct agttctaaag ctgctttaat ttgggttgct
     9781 tttgataacc caattccatc tatattacac agctcctcta ttgtcatatc ttctaaatgt
     9841 ctaataccct gaatatctct atttattata tagttggcta attcaatagc atttttattc
     9901 ttgtcgccag ttcttaaaag tatcgccaac aactcagcat ttgataagct ttttacccct
     9961 ttggcaagca tcttttctct gggtctttcc tctggtgcca tttcttttac cttaatggtt
    10021 gaattaaatg actttttcag acaaatcaca ctccataaaa aagatttata ctaaaatatt
    10081 tttttaatag gtcgcttaac cttgaaattg gaagaccaac tatattaaaa taatctcctc
    10141 taatttcttc aactaacaaa gctccatatc cttgtatacc ataagctcct gctttgtcaa
    10201 atgactcatt agttttcaga taatcctcaa tatcttgctc tgataacgtt ttaaatttca
    10261 cattgctgat tacatagtca attacctttt tatcttcgca caagtttatt aagctaatac
    10321 ctgttatgac ttgatgctct cttccagata gtctttttaa catatctctt gcacaagact
    10381 catcttttgg ttttcctaaa atagcattgt ctaaaacaac aactgtatca gctccaataa
    10441 caacatcttc attatgttca gatgctacag acatactttt ttcaaaagct aacctcataa
    10501 ctaaatgttt tggtgtttca ccttccaata taatctcatc aatttcattt ttaattatat
    10561 caaatcttac atttgtattc tctagaattt ctttccttct tggagaggct gatgccaaga
    10621 ttatattcat ttattcacct catttgtacg taatttgtac ctatttagtc tatcactata
    10681 ttgtaaaaaa ttcaacagaa atgtcgaacc ttttttgtta cactattgtt atatttatta
    10741 ccattagaat aaatatacat aaaatagagg tatggaaatt attccatacc tctgttttat
    10801 gtactcatta gagatatgga aattattcca tatctttatt ttgtccatat tacaaaattt
    10861 taatagcttt ctttggacat ttttccatac ataaatggca tcctacacat ttatctgcat
    10921 ctaccttatg tttttctttt aattctccct ctattgcatc aaacttacat tgttttttgc
    10981 acactgtaca tccaacacaa agttcttggt caatagtaac tttctttttc ttagttatgt
    11041 cacctgatat tacttttgta gggcattttg ctacacattg catacaacct acacatttat
    11101 tagggtctat cttagctatt ttgtcttcaa atattattgc atcaaattta caagctttta
    11161 cacacattcc acagccaata catccagcag tacatttttc cttaacagct ttaccaaact
    11221 ctttgctatt acactctaca actacttctt gactctctgg ttttgtgatt attataccct
    11281 tagggcaaac ttctttacat tttccacaat ttacacactt ttcttcatct attactgcta
    11341 ctccatcaac tatagaaata gcatcaaatt tacaagcatc tttacatgtt ccaagaccta
    11401 agcatccaaa tttacacatc ttggcacctg agtttaaaac atttgctgct ctacaatctg
    11461 atattccttc atactcatat ttatcttttg cacttgaaca agttccttta caaataactt
    11521 ttgctacttg tttctcacct gcttcagcgc ttattcccat tatttctcca acttttgcac
    11581 caacatctgc tccacctaca gggcaaccat taactggtgc attgccttca actatcgcat
    11641 ttgcaagacc tccacaacct ggaaatccac aacctccaca gttggctcct ggaagtactc
    11701 ctagtatagc ttccactctc tcgtctactt ctacagcaaa ctttttagat gcaaaatcta
    11761 gtactatccc gaagattaag cccataattc ctaaaactaa tacagctgta agtatcacca
    11821 ttttcacccc tcttttttat agctttataa gtcctgtaaa tcctaagaaa gctattgaca
    11881 ttaaacctgc tgatataagc gttataggga aacctttaaa tgcttctggt atatcagcta
    11941 attctagtct ttctcttata cctgcgaata ttactattgc taaagtaaat ccagctccgg
    12001 ctccaaatcc atttattatt gtttctacta aattataact tttttgaaca ttaactagag
    12061 ctataccaag aactgcacag tttgtagtta taagaggtaa ataaactcct aatgcttgat
    12121 ataaagatgg actcatcttt tgaattacca tttcaacgaa ctgaactata gaagctataa
    12181 ccaatataaa agctatcgtt tgtaagaatc cagttccagt ttttactaat aaaatctgta
    12241 taaaataagt tataattgaa gctagagtta aaacgaatgt aactgcaact cccatcccta
    12301 ctgctgtatc aaccttctta gaaacaccta agaaaggaca tatacctaag aattgagatg
    12361 ttataacgtt attaacaaga acgatactta aaaataaaag tattaaattc atttattaca
    12421 cctccactat gcttttttac ttcttaattt attaaatcct gcaaataaga atcctaatgt
    12481 taagaatgca cctggtggta atataaatat taatactggt tggaaagatg ctccaaataa
    12541 tgtcattcca aataaactac catttccaag taattctctt actgcaccta ttattgtaag
    12601 tgcaacagta aatccaagcc cttgacctac accatcaact attgaaggca tagcccctgt
    12661 tttgaaagca aaactttctg cacgagctaa tattaaacag ttaacaacta ttaatggtat
    12721 atatatacca agagccttat caagagcagg aacatatgct tttaaaagca tacctactat
    12781 tgtaacaaat gtagctataa ctactataaa tataggtatt cttatcttat ctggtgtaat
    12841 ttttcttatt aaagatataa ctaaatttgc acatattaaa actgctgctg ttgaaagacc
    12901 cataccaatt ccatttattg ctgaagttgt aacggctagt gttggacaca tccctataac
    12961 ttgaacaaat gttgggttct catctattag cccattttta aatactttag ctaaattcat
    13021 aattaaccct ccttatttat taagagcact attgaaaaca tctatagcag catttactcc
    13081 tgtagtaact gctgtagatg taatagttgc acctgatatt gctaatattt gattatctgc
    13141 tgttgtactt ccttttgcta cttcaagagg ttcagcagtt tttcctttgt attgaccttt
    13201 aaatgcatca tccttagctt tcgctccaag acctgctgtt tctgacatgt taccaatgtc
    13261 aacacctgta acttgacctt cagatgagat acctaccata acttcaattt ctccaccata
    13321 tccacttggt ttagctttta aagtgtaccc aaccacttca gaaccatcta aaccttcata
    13381 cacttcagct ataagaccat ctccaaggtc tttatatgta cttttatcca tttctttaaa
    13441 ttcttttgct tctggaagta ctgcttttct aagttcatta tttgcttgta tatttctttg
    13501 ttctattact ggagctgtaa cctgatttgt agctccaaga gctaatgcag ctattgcact
    13561 tatagcaagt aaagtaccac ctaatctcac catactgttc attatttagc cacctcccca
    13621 aatactctat ttctaacaaa cttatctata agtggagcaa gacagttcac taatagtatt
    13681 gagtaagata caccttctgg atatccacca tacattctta taacagttgt tataagacca
    13741 gctaatacag catatattat ttgacctttt ttagtcatag gcgaagttgt ataatccgta
    13801 agcatgaaga atccacctaa cataagacct ccagcaaaca gttgatatat tgcgaaagtt
    13861 atattaaatc cacctaaaag gaatgttaat ataaatacag ttgctatgta aaatactggt
    13921 ataacataat ttattatgcc tttatacatt aggtatactc cacctaataa taataatatt
    13981 gctgatgtct cacctataca tccaccaata ttccctatca tcatatcagc aagactaatt
    14041 ccattgctag aaaggtccgc tagtcctgct gctccatttt tcaaaaagct taatggagtt
    14101 gctgtagtaa ctgcatctaa atttttacct atccagttga cacctggttg agtccaagca
    14161 gtcattgcta ctgggaatga tgctaataaa aatgctcttg cagcaagtgc tggattgaca
    14221 aagttacatc caattccacc aaataccatt ttaactacta atattgcaaa tattcctcct
    14281 actagacaca tccaccaagg aagtgatgct ggtacgttaa atgctaataa taatcctgtt
    14341 acaacagctg aaaaatctcc tatagtactt ttttgcttcg caaatttttg atataaaaat
    14401 tcagtaccta ctgtaccaag tatacaaaaa aacatagcac tcaaagcatt aagtctaaag
    14461 aagtatactc ctgctactgc tgctggaagg agtgctataa taacttgttt cattatatat
    14521 gaagtatctt cattacttct cacatgagga gaagatgata ctatcaactt attttccatc
    14581 gtttttcccc cttaactttc tttatttctg agcagcttgc tttcttctct ttgctcctat
    14641 ttctctcttt gctgatctta tagattgaag taatggtctt cttgctggac aaataaatga
    14701 acaagaccca cattctatac aatccattgc tctatgatat tcagctgtgt catagtcatc
    14761 ttttaaagaa tatgcactta tgaaaagtgg ttgtaagaat gatggacata catctgtaca
    14821 tcttccacat cttaaacagt tttgaacatc tggagtacgt gattcttctt catccaaaca
    14881 taaaattcct gaagaacctt tgttagtcgc tatttcagta gtatattgag ctattcccat
    14941 cataggtcca cccattataa ccttaccaat cttcttatct tctttaaatc caccacattg
    15001 ttctattatt tctgaaacta atgttccaac ttttgttatt aggttctttg gctctttgat
    15061 gcaactacct gttactgtag tgattctttc taccaaaggc atacctgttt taatagactt
    15121 agctatttgt gctgctgtgg caacgttgtc aacaactgca cctgctgcta ttggtaatcc
    15181 accagatgga acttctttgc ctgtacatgc gtaaataagt tgtttctctg ctccttgtgg
    15241 atatttcact tgaagaccaa caacttcgat ttcactataa tctttagcta cattttgaat
    15301 tgcttctata gcatctggtt tatttgtttc aattcctata aatccttttt taacatctaa
    15361 taccttcatt aatgctctta aaccaaatac aacatcttct ggattttcaa ccattaatct
    15421 gtggtctgca gttaaatatg gttcacactc tgcaccattt aatataacta cttctgcctt
    15481 gctatctggt ggaggagata cttttacatg gttaggaaat gtagctccac ccatacctac
    15541 tattcctgcc tcttttatga tacctactat gtcttctttg ctcaaatcct ctaactgacc
    15601 ttttggttga acactctcat gtaattcttc cttaaagtca ttttcgataa ctacacattg
    15661 agctgaacca cctggtactt catgttgttc aatagcaata actttacctg atactgaaga
    15721 atgaacgtta catgaaacaa aaccttgttg ttcacctatt ttttgcccaa actttacttc
    15781 atcaccaact tcaacaatag ttttagctgg tgcccctata tgttgctgaa gaggaatgta
    15841 aactatcttt ggagcttgag ctttttcaag tgcctttgtg ttagagtact cttttctata
    15901 tggaggatgt atccctccct taaaagttaa gagtttcatt gttttacccc cttatctata
    15961 aaaaaacatt ttttctgcct tctataagta tactatatat attaaaaaat cttaacaatt
    16021 gttaaaaaaa tatccgtatt tttataattt attttataaa tcaatgtctc tatattaagt
    16081 caaatcgagg aaaaggattg cttaattaaa caatcctttt cattcagctt tctaaagtcc
    16141 aaattttctg tattttattt tatagaattt ataaacatag agtactcctg catagatgat
    16201 aaaagtagac ttttacttac actatatttt tcttcatttg ctgcttttga agctgtatca
    16261 attttttcat tcacattctt tacatactct attaaattat ctttaaataa acgcatttca
    16321 gaataatcaa ttttttcagc ttcttttgat atattttgtg atattgcctt tctatttgtc
    16381 aaaatagtat tatatttttc catatctaca ttattttcag cattcgacca aaaacttgat
    16441 tcttctttaa agtttgttat taatttattt aattctttag atatactatc tatataagca
    16501 tagttacttg tatactctaa agataacata ggtgcatcta agtgtgataa aaatgcatct
    16561 ggaaacacct ttcttacact gcttatctgc tttctaacat cattttcatc aaaagaggaa
    16621 tatgtctgta ttttttttac tccatccttc tccataactg aaaaaggtat atcattgtta
    16681 actaatgatg tctgtatttt tttcaaatca tcattattat ctattgcagc aacttgaata
    16741 gtgtacatat cccagccttc tatagtagct aatttaactt cttctggctc tttagtgtta
    16801 tttaccgctt tttctggatt agtttcttgt ttatcatctg aattggtttg tgatttagat
    16861 ttttttccgt tttttattga atttaattca tcagatatat ctttataagt tatatctgat
    16921 gaattattta gaaatggtat tttagccgat acatactcca atatcttgct atcttttatt
    16981 tttgtataag aataatagcc aattagacac aagcaagcaa tcgttataac atatttacgt
    17041 aaatcaatct tatgtctatt attattaaat cctctgtata tcgtttttct tctattcatt
    17101 agtttgtccc tcccaaaatt atattattaa taaagtatat ttttaagagt cacaatttat
    17161 gaatataaat aattatttat tctaattttt taataagaaa ttgtacttac taaacaaatc
    17221 ttcttgcacc aagtaatact ttagaccaat atgaactagt taaattatcc actttaacct
    17281 tattaggatt agtttgagta ccactacaat gaataaattt actattgcct acatatatac
    17341 ctacatgatt agttgttcca tcaccatcag tatcaaaata aactaaatct cctggtgcat
    17401 aattccccat agaaattgca cttccaaaat tagcctgttc tctagaaact ctaggaatag
    17461 aaacgcctac agaatgttta aaaacatact gtgtaaatcc agaacagtca aatttatcag
    17521 gtcctgaagc tccccattga tatggtattc caataagagt atatgcaaaa tctacgattg
    17581 ttgaaccttt tgctgtagat ttatctgaat ttccagtaaa tgatggcttt gagttattat
    17641 tagattgaga attttgatta gatgatgaat ttgaattttc ttttgtacct tcattagtct
    17701 cagaaatata actgccactc acccatccag ttgttccatt cgatagtttt accttatacc
    17761 aaccattatt tttagctttt aattcaacaa catctccacc atttaatttt cctattatag
    17821 aatagcttgt cccaggacca cttcttacat ttaaactcac agtagatgtt accttaccat
    17881 ttttaccttc aattgattct tcgctagatg gttttttatc agagttatta gtactatttg
    17941 aattactgga attattcgct ccaacatctt ctgacgtttt agagatatat tggctactag
    18001 cccatccagt aaccccattt gatagtttta ttttatacca tccattgctt tgttctagta
    18061 actttactac ttctccatta tttgctttac caactaatga atagttagta cctgcaccac
    18121 ttcttacatt cagtctagag ctcacattta ctttaccatt tccactgata gttgttccac
    18181 ttgaagttga attatttgga tttgatgtac cttcagatga accacttgtt gatatgtatt
    18241 ttgcacttcc ccatccaaca acagagcttg atacccttac tttataccat ccattagatt
    18301 tttctaaaat ctctacagtt tttcccttgt acaattttgc taccttatcg caatcagagc
    18361 ttggtccact tcttatgttc aaggcacttg ctgttactgt tcccttctca agagcacttg
    18421 catttatgga gctaacagat actgctactg ccccaattcc taaagccgct atagctttct
    18481 tcactactat cactcccccc aacaaatttt tatagtcata aatccataac attattatcc
    18541 atttttagta cctataattt aatgataact tattctctta ttaattgtaa agaaattata
    18601 aacatatcct taaaattaat gatttttagg aagtatttca atccaataat tatctgggtc
    18661 cgctataaaa taaattccca tactttcatt ttcaaaacat atgcaatcta aatctttatg
    18721 aagttttttt gcctcatcaa actcctcaac ttctaaagcc agatgaaatt cattatctcc
    18781 taaattatat ggtctgtccc aatctctaag ccaagttaat tctaatgtat gactagtaat
    18841 gccatctcct aaataaacta atataaaact tccatcttct gcttccttac gctttacctc
    18901 tttaagccct aaagcttttt tataaaaatc taaacttttt tctaagttag taacattgaa
    18961 attgttatgg caaaaattaa acttcatttt gaaatcactc tccaattttt atttttttat
    19021 attatatcat tattataaat ttatttaaat catattaagc taaaaatttg aacgatgata
    19081 aacaattacc agatactggt aaattattta aaggaatatg tcaaaaaaag aataagctct
    19141 ttcaaatgca taaaagattt atacctaagt tatacttaat catgcaaatt gacagaactt
    19201 attctttaaa actttaactt ttaagttttt ctttgatgat ataatttatt actttttttc
    19261 taatatcttc agcattataa tcatcttcta cttctatatc caaaagtttt gctattgacc
    19321 tcatatcttc tctagtcttt gacctatagc ttgatattaa ttcatctttt attttctcag
    19381 gctctaaaag atattcttca tctcctcttt tgaaaacaac gtatttttga gcatatgaac
    19441 ttctattgta gtatatatat cttgatattt ttcttaaaat ttgattatat gaaagtcgct
    19501 tgttaatatc aagttttaag tactctgaaa aagcaaatag ctcttttttt gatttaaata
    19561 atgcttcttt ctttatagtc cttgatattg aagttacact ttcttgatat gcacactttt
    19621 ttaacatttt taaatatact ctattaagac cgatactttg attgaatttt tttatattat
    19681 tattaataat cttatccaag ttaccttcaa agtatttttt tgctcctttt tgtgatacat
    19741 aactctcaag ttctttgtgg gccatatcaa gtatcatttt ttttaaatcc tctttatatc
    19801 ctctagattc catgatactc cctcccttag ctatttatag tatattcaaa aagctcaaga
    19861 aatgtgagtc attacaaatt ttttttactt tttatgtata tattaattta aaaggggaga
    19921 taatagtaat gtaaaatcaa acatactcaa tctcccccat ttttagacct ctattactcc
    19981 cccaatagag gtcttttttt agtttattaa cttctattca attcccttta gttcaaatcc
    20041 taattctgct attacttctt ttaatttttc aatagataca ctatctttca tatctacaga
    20101 tgcacacttg ttttctaaat ctacatctaa aacttcaata ccatctatat cttctgttaa
    20161 tgcagtttta agatgattta cacaatgacc acaactcata ccttctacta atagtttctt
    20221 cttcatttaa ttacctcctt ataccctata agggtatttt atcatatagt ttatactttt
    20281 aaaatagaaa ttaatcattt aatttgattc attcgatttt atatctagat tagatattcc
    20341 ctcatataca tcaaaatcat ttggagtaat tttacctttt aatctactac tacttacaat
    20401 atagttgttt ctaacagcta aacttataaa tgttgcatta tcttttatat atgtctgtac
    20461 atctttgtat gctttttttg tttcaatttc agatgtagaa cttgtaagtg cagacatata
    20521 tccatttagc ttatcatcag tatatccact actagctata atactacttg catctggtat
    20581 acttgataat ttccatccaa ctaatgctaa atcataatct ttagaattaa gagcattttc
    20641 catgtcctta tctgacagct gatttactgt actatttatt cctatagcct ttaagttttc
    20701 atttattatg tttgcagttt ttattctctc actattatct ctgtttacta ttatttttaa
    20761 gttcatctca gaaagttttt tctttacttc ctctttttct ctattttgtt tctcttcagc
    20821 ttcttttttg atgctatctt cttccgcttt tttagctttt gcttcttctt ctggagtaag
    20881 cttctttaaa ttctttttag ctggtttttt ctgattcttt attttattgt cattttgatt
    20941 tactggattt acatttgcat attctacctt agcaaggcac tctagtgctt tatctttatt
    21001 aaactctaaa tccttcattt cactattata gtattttgat tttgaattaa gtggaaaatt
    21061 aactggagta gcatcatcca tataaccttc actaataatt ctatctttat ctatagagtg
    21121 cgcaattgct tttctaaaat tgacatcttt aaaaaaagga ttattataat taaataatac
    21181 acactcataa tctctacctt gatattttgt tatattaaac tctttttctt gaaacttact
    21241 taaatcattt aatgtaacat tggttatatc actatcgaga gccataacca tagatgtcct
    21301 tgcatcttca ttaggcacca tacctacttt tatgttcttc atggtctttg gaacttcttc
    21361 atagtagtct ttgtttacag ataaaaccat tccttctctt tctgtatatg attctatttt
    21421 atatttccca tttcctatca tattattatt cttgtcattt acatcttttg aatctaaatg
    21481 actttgagat actattggaa aaattaaact atcaattgag aaagcatatc tagctttaaa
    21541 ttttattgta aaatctttat ctgatttaat attcacagaa gctatatttt tggtaaattc
    21601 attatatgga ctatctgcac ttttttgaat taaaccaata gtatagttta catcatttga
    21661 agtaacatct tttccatcat gccactttgc atctttcagc tttatatcta tactcattcc
    21721 atcctgagct atattatact ccttaactaa ttgaggaatt acattgtagt tctcatctat
    21781 agtaaataaa ctatcataaa ctaaattcat tatataacca acagacttat cagtattagt
    21841 tataggattt atagtttttg gagttaccat tgttaagttt atatacttag catctataga
    21901 actttgactt tgtaaacttg aatcactact actttgtttt gttttactat tactacaacc
    21961 aaccaccata agagttatag ctaaaacaac tgttaagact tttattctct tcattagttt
    22021 tttcctttct tgccatatat cttattatat tgttcataat tattttttac tttttctaca
    22081 tattttgaag tttgcttaaa aggtatatca tgtagatttt cgccatcttt actatactca
    22141 ttattttcta accatttttt cacattacct gaaccaccat tatatgcagc tatcactaaa
    22201 tctaatttac caaattcttt gtataactta cttaaatacc aacaaccaag tcttatatta
    22261 gtctctgggt cgaaaatatc cacatttttt agatttaatt cctctgctcc ccaatctcta
    22321 gttatgtcta atatttgcat taatcctttt gcttcttttt ttgaaacagc agaactatta
    22381 aacttacttt cggctttaat aacactgtaa actatatttt catctaaatt aaattcttta
    22441 gaatactttt ctacatattc tgaatatttt ttaggatata aaaatttatg tattactttg
    22501 ctttccatta atagtgctcc aaataagatt ataaaaatag atagaatcaa tactttctta
    22561 ctattcacgc caattctcct tcatgtactc aataaattta tgtgctttac tttctaattc
    22621 agttattgtt cccgaattat ctattatata atcaccatat ttggattttt cttcctgact
    22681 catctgtgaa tttatcctat taagtgcttc ctgctcactg caattatctc tcttttgtat
    22741 tctactaatt tgtacttctt gtttacaagt aactactagt agcttgtcaa ccatatctaa
    22801 aaaaccactt tctaccaata ttgccgcatc taatactact atattttcgc ctttttttct
    22861 caattcttct atttcactta ttattttttc tcttattcgt ggatgtgtca aattatttaa
    22921 cttcttaagt ttttcttcat cactaaaaac tattttccca agagcttttc tatttagagt
    22981 tccatcatca ttttttatac tttgcccaaa atggacaaat actttttcta ataacaactt
    23041 atcctcaaat atcttcctgg atataatatc agcatccact atagaaatgt taagatttct
    23101 aaatatattt gataggctgc tttttccaca gcctattcct cctgtaagtc ctaatatcaa
    23161 cataaaatca cctactttgt ctcataccaa gaactgccta catttaaatc tacatctaag
    23221 tgaacatcta tatttacagc attttccatt tcttctttta ctattttctt aactatatct
    23281 atttcatcat caattgcttc aactatcaat tcgtcgtgaa cttgtagtat aagttttgat
    23341 ttcaaattgt tctcttccaa ttttttatga acatttatca tagcaatttt tattatatct
    23401 gctgcacttc cttgtattgg tgcattcatt gcaaatctct ttcctctatt tctttccata
    23461 aaattgcttg actttatttc tggtatatat cttcttctgt ttaaaattgt tacagcatat
    23521 ccatcttcac tagccttttc tactgttgtg tccataaact cttttatttt atggtattta
    23581 gcaaaataac tttcgatata ttctttcgcc tttggaacag gtatatttaa atcatcagct
    23641 aagccaaagt cacttttacc atatataata ccaaagttta ctgctttagc tgcacctctc
    23701 aattcactag tgacatcttc cataggaaca ttaaaaactt gtgaagctgt tttagtatga
    23761 atatcttcat gatgtttaaa tgcttctatc atattttcat cctgactcat atgtgcaaga
    23821 actcttagct ctacttgtga gtaatcggca tcaaccaact tacagttatc atctgcaata
    23881 aacacttttc ttatttttct acccatttcc atttttatag gtatattttg aaggtttggt
    23941 tctgtagatg aaattcttcc tgtagtcgtt atagtttgat taaatgatga atgtattcta
    24001 ttactttctg gatttattat atttaaaagt ccttcaacgt aagtagaatt taattttact
    24061 atttgtctat actcagttat cttatctatt attggatgct tatctcttaa tttttctaga
    24121 acatctgcat tagttgaata tccagtttta gtttttttaa ttattggaag ctctaatttt
    24181 tcaaataata tgacacccaa ttgttttggt gaatttatat tgaatggctc tcctgataat
    24241 tcataaattt ccttttctaa tgtagctatt atttctttaa actctacact caattcatcc
    24301 aatatacttt tgtctacttt tataccttca tactccatat gtcctaatac ttctactaaa
    24361 ggcatctcca catgataaaa aagaccatcc atactcatat ccattagact tctttccatc
    24421 ataggaactg tttctttaac tgtgcatatt atttgaccca tatactcagc taaatcctca
    24481 aattctaaat cttcatagtt tttagattta acaccttttc ctaataattc ttcctttgat
    24541 ttaacctttt ttgataaata tttcatagct attgcactac aatcatatga agtagatgaa
    24601 gttgaatcta ttaagtactc agatattgtt atatcaaaat acatattttc taagtttata
    24661 ttatatggtt ttaaagatat ataatcatct tttaaattat atccatactt tttgatttca
    24721 ttatttgaaa atatactatc taactttgac acttcatttg aatctacata atatattttt
    24781 tctccatcta cacttataaa aatatatatt atattttttt caagtatatt accttgtcct
    24841 ctaacagttt ttaaaataac ttgtcctttt tcatttactt catctataaa tttttctata
    24901 tcttttaatt ttaatatttc tattttttct tctacttgtt ctgtatcatt tgaatcgacc
    24961 aaatcaacta gccttgacaa aaggcttgta aatccaaaat atctaaattt atctaaaagt
    25021 tcatctttat cataatcgcc aaaaatcata ctttctaaat ctacttctat tggcacatct
    25081 cttataattg ttgcaagtct tttactttga atagctattt ctttattttc ctctattttc
    25141 ttttttacac tgcctttaag tttatctgta ttctctaata agttctctat actagaaaac
    25201 tcttttataa gctttatacc tgttttctca ccgattccag gtactccagg tatattatcc
    25261 gacttatctc ccataagacc ttttaaatca ataaattgtg ttggagtcat ctcgtatttt
    25321 tcaattacag aattaaagtt gtattcttca acttctccaa ctcctttttt tgttataaga
    25381 gtagttgtat tatctgaagc aagttgaata gcatctttat ctccagttac tatgtatacc
    25441 ttatagccat catcttctgc ttttttagaa acagttccta taatatcatc tgcctcatag
    25501 ccatctattt ctaatctatt tattttaaat ttatctaaaa ggtcttttag tggctgtaat
    25561 tgttctgcca attcatctgg cattcctttt cttccagcct tatattcttt atactctaaa
    25621 tgtctaaatg taggtgcttt tctgtcaaaa gctacactta tatgtgttgg tttatatata
    25681 tctatcattt taaatagcat tgttgtaaac ccatatatcg cattagtctt taacccttct
    25741 ttattgttca tttctggcag agcataaaaa gctctgttta ttattgaatt tccatctatt
    25801 ataattaatt ttttttccaa attatatcac tcctaaaaat tatctatttt tgtaacatat
    25861 atattatata ccaatatagt gttatttaat attcccataa taataatagt atattaaaat
    25921 taaatatgtt gcaaacaata tatttttttg ctataataat atacatgaca tgcccgagtg
    25981 gtggaattgg taaatacaat ggattcaaaa tcaactgtgt tgattcataa gtttttatga
    26041 tgttttacag tttgatgagt attttgtatt caatattcct cttgcatatt cttggaaaat
    26101 ctggtaggat atacaagtag ttcggattta aaatataagc cgctgtggcg gaactggcat
    26161 acgcatacga ctcaaaatcg tacgggaaac catatgggtt cgagtcccat cagcggcacc
    26221 aataaaaaaa actctttagt atatactaaa gagttttttt attgtaatat tctttcatct
    26281 ttatttctag tcttgtataa gtataaatac catagtcata acttcttgaa ctcctaaaat
    26341 atatctaaac aaagtaggat tttttatgta ttcacttaat aaatccatac ttcttatcat
    26401 attgattttt tcccactctc taaaactttt ccttctctaa aaatatttat aaccaatcat
    26461 cattattcag tataatgatt ctatattatt ttaaagtatt tgtcatttaa aacaaacttg
    26521 tgataaaagc atatctgaaa gtattctgat tctaatactt aataaagagt tctttttaca
    26581 gttatagata taaacaactt ctatcttaat agactgtata gaagcacaat caaatgcaaa
    26641 cacatatagt taagtaatat gtccttgatt tttctttatt attttattgt aatagcttta
    26701 ttaattcatt ataatattac atcatttaaa aaaaattata tgaaaagtca aaatttacat
    26761 atagattaat taaacttgta aaaacacata taaattcgta caattaagta cttaaaactt
    26821 gaaaatagtt actttgctat atattttaga taaagatata atttatttgg ttaagaaaag
    26881 aagtggtaaa tataaaaata aggagtctaa tatgatattc agtagtttaa tatttttatt
    26941 tttattcttt ccagttacac tcatttgcta ttacttggca aatcctaagt ataaaaatgt
    27001 tatgttactt ctagcaagta ttgccttcta tacatgggga gaaccaaaat atattttttt
    27061 gatgatacta tcaataatag taaactatat atttggtatt aaagtttctg gcagtaaaaa
    27121 taaaaaaatg tgggttgtgc tttctgttat ttacaatata tctattcttg ctgtatttaa
    27181 gtatagcaat ttttttatag ataatattaa ttttttattc aatacagata taactatacc
    27241 tgaggttaaa ttacctttag gtatctcatt tttcacattc caaataatga gctatgtaat
    27301 agatgtatat agaaatgatg ctaaagttca aagaaaatta gctaatttag cattgtacat
    27361 aagtttattc cctcaacttg tagcaggtcc tattgttaga tatcagactg ttgcagatag
    27421 cattgagtat agagaacaca attgggacaa atttactcaa ggtgtaaaca gatttgttgt
    27481 tggtcttgga aaaaaagtaa ttctagcaaa tcaattaggt gtaatagcag atggtgtatt
    27541 taataagtca gctggagatt tatcaagatt tgaggtatgg ctaggtatag tttgctatac
    27601 acttcaaata ttctatgact ttagtggcta tagtgatatg gccattggtt taggtaaaat
    27661 gtttggattt gagtttttag aaaatttcaa ctatccatat atctctcaaa cagtatctga
    27721 gttttggaga agatggcata tatctttagg tacttggttt aaagactatg tatacttccc
    27781 attaggtgga aatagagtct ctaaggcaaa actatataga aatctatttg tagtatggtt
    27841 tttaaccggc atgtggcatg gaactagttg gacttttatt atattgggtc tatattatgg
    27901 aatattaata tcagtagaaa aagcattctt agaaaagttt ctatataaga tgccaagaat
    27961 tgtaagacac atatatctac ttcttatagt catgattgga tgggtatttt ttagagttga
    28021 tgatttacca gcagctatta aatttatagg tattatgttt ggtgctggaa attatccggt
    28081 tatcagtaat gcattcaatg tgtttataat tgaatattgg tatgtaattg ttggggcaat
    28141 ccttctatca actcctattg taaaagtttt aaaatcatta ttaattaaga aaaataaaaa
    28201 tacattaaat agcacattat atcaagttac taatatggtt ttcattgttt cttgtatgtt
    28261 tattgtaata ataatgttaa gtagctcaac ttataatcca ttcttatatt ttagattcta
    28321 attgggaggt ataaacatga gtaaaaaaaa accaaggatt gttgccattt catttttaat
    28381 tatagtattt ggatttttca tactaaactt cacacttcca aagaaaaaat taagtataac
    28441 tgaaaataga aatcttgcaa aatttccgac tgtagaaaat ttaaaaaaag gtgactttat
    28501 agccaagttt gaagaatatt ttaatgacca ttttgcattc agagatagaa tgatatcaat
    28561 aaatacaaag gctcaagcta gtttaaataa aactaaggta ggtaactatt atctaggaaa
    28621 agataactgg atattaggta tgtttccaga aattttagac caaaaacaat taagtcgata
    28681 cgaaaagtcc attaattatt tatctaatct aagtaaagat atgggaaaaa atgtgtattt
    28741 tacaatgatg ccacataaaa ctaatatgtt aaaacatttg tatcctaaat atgttgataa
    28801 tatggataat atagacataa atttaaagaa ttttaaaaat agattaaatc cagatttaat
    28861 taaatatata gatatggatg agtatttttt aagtaactat tcagataaag aaagagaaaa
    28921 tttatatttt aaaactgacc atcattggac tggatatgga gcatttgaag gctttaaaat
    28981 gatggcatca aatatggact taggtctatc taagcaagat ttagacaagc attttagtag
    29041 ctataaaaag tctataatta ctgataagaa atttatagga agttataatc aaaatataga
    29101 tatgctaatt aaagaaaatg aatatgtagt ttatatgaca aaagataacc aagattatag
    29161 ctttgatata aatggagaag aaaaagaaga aaaagaggtt tatgcaactg aaagagataa
    29221 taaagagtgg gattatggtg gtgcatacat tagaggagct aaaactaata tattaactat
    29281 aaaaaaccct aaagcattag tgaataaaaa aatactaata tttagagatt catatcaggc
    29341 tcctacaaca cttttatttg ctgatatgtt taaagaagta gagatagcag accctagaaa
    29401 tataaactca atatataaaa catacaaaga gataatcgag gaaagtaatg cagatattgt
    29461 aatgtttatg tataatagtt ctgggtttga ttcaatgata gattcaatga tagataaagg
    29521 aataaagtag taaataaaaa gattaaacaa aagtattatc taactaaaga tggatggcta
    29581 ttaggcaact ttgccaaatt attatctgat tatcatataa aatcttactc caaagccatt
    29641 aataacttga gtaagttaaa tagaaaaaaa gatttttact ttgtttcact tcctcataag
    29701 acaaatatgc ttaagaactt gtatccaagt ggtataaaag gtaaaaataa tatagatatt
    29761 aacaaagaaa acttagaaaa gcagttaaaa gacataaatt tcttagatat agatgattac
    29821 ttttataaaa gttttaccga aaaagaaaga gaaaacttct ttttaaaaac agaccatcac
    29881 ggaaattcat taggagcatt tgaagaatat aagtttattc ttgataaatt agaccttagc
    29941 ttatctaaat cagaaataga tagtcattta aaaagataca gtactcgata tgtaaatgac
    30001 tgcgaatgta gttttattta tgtataatag ctttggattt gctggaatga tacaagaaat
    30061 gattgacaag ggaatagcat aacaatttga atcaactcct ttttatacaa aaaatagttc
    30121 tcaataattc ctaatctata tgataattta gtacatctct ttaacaataa aaataaaatc
    30181 acataaattc ttataccatc acttatcttt atgataaatt ggttgagaaa aaattttata
    30241 atttatatga tatgtaatct taattaattc tttacttttt aattctttat ctactgcaac
    30301 ctttgataaa agaaaccatc caagactatt aatatgaatt tatataaaaa ttactttcaa
    30361 ataaagtact gcaatatttt tatttaaagt atctataatc tttaaccaca aaaagccaca
    30421 aaatacaatg tatacctatg gctttttata aatttacata attgtatata aagatatact
    30481 ctaaaactgt cttaagaatc taaagtttaa aaatacaata tttttattgt gaatttaaac
    30541 tttttattac aactttttat ctaatttatt gtatacaaca acactacaaa taaattgaaa
    30601 taaaataagc aatccaagaa caactaaaac ccacttgctt attaccatta cagaaaatac
    30661 actcaatata gaaacaataa atataagaat tacaagaaca taggacatga tttgattagt
    30721 gatacgtcca gctttatcac gtaacataat tcttctttca tcattcatct ctatcctttg
    30781 gttttttatc ttttcttcat aatctaatgc tctttcaggc ttactccaat acatatattg
    30841 aagaatcata catacacctg gacctaaagc agctccagat aatccccaaa taaaagcctc
    30901 aaatgaaaac tcagtaaacg tagccaataa aacaagtaaa attccacaaa taaaatatac
    30961 tattccaaga tataacatat tctttttcat ttttactcct cctcataaat aaatatttct
    31021 tcaatactcc tatcaaagta tctagctatc ttaaaggcta agatgataga aggattatac
    31081 ctaccatttt ctaatgaacc tatagtttgt cttgatactt gcaaaacaga agcaagttct
    31141 tcttgtttta tgcctctttc ttttcttatt tcttctaatc tatttttcac atctatcccc
    31201 ctttaatatc tcaactacgg aaagtctact ttccataatt atacaactat attccattta
    31261 tgtaaagctt actttccata tttacaaaaa aataacagac tattttcaga ctgtaatttt
    31321 agaatttcat gttgtttatt aattttaatg ttatttatta attccatatt atttattaac
    31381 tttaacttgg tttctgaatt ggaatccaaa cttctgtagt ataatcagga gaattgatat
    31441 cgccattggg ataaagttca atatctggta aattagaata cacataccca gaacttggta
    31501 accactcagt aataattctt ttttgcaact cctgtattgc cagagcattt ggcattggag
    31561 aaacacattc aaatactgcc catgtacctg atggtattaa gtattcatga gtatcttcta
    31621 atataggctt atctgttggt gcagcaatat aataatctaa gcccttacta tttgtacaca
    31681 cactaactcc aagcaatcca caaggttcgt tatttattaa ctctgaaagt ttatcaattg
    31741 ttccattttt tatgcattta gcccataact taggaacttt ctcaaaacac tcttctacaa
    31801 tcatgttcat actttctttt ataccaacaa tacgaaatcc tttcttttct acaatacgat
    31861 attgcatttc tacatttcct tttacataaa tgcttaatgt catcttagga tatgctttta
    31921 aaacaacgcc ttttgctcta gctgcagatg gagaaatgtt atgtatattt tgaaaagctc
    31981 tattaaaaga tgttggtgaa tcgtaaccat acttctcaga tagttctaaa attttgatgt
    32041 tactgttctg cagttcaaat gcagccttag tcatacgtct tcgtctaata tattcagata
    32101 ctggtacttc cgcaatatat gaaaacattc tttgaaaatg aaaagttgag caacatgcaa
    32161 tttttgctgc ttctgcataa tctattccac tttcaagatt ttcttcaata taagtaatag
    32221 cttgatttaa tttatttatc cattccattt aatattacct ccaaacaaat tatacagttt
    32281 aataaaataa tatacctctc tattcatgca caaaattgta agcatttaaa ttcataagca
    32341 ttttctaatc catcaataca ataaatgtaa aaattatatt atacaataaa aaagttcaat
    32401 aacattatat aatattattg aacttcttat aaaaattaat ttaagtgtag ttaaattaag
    32461 tattacacta tcttatatat tacaatatcc aactatcttg tagtcttctg gcactttata
    32521 atctttatct ggagtaccta aattccattt taactcaaac atagttgcac ttattattgt
    32581 tgcaaaataa agcataacta taccaatatc tattttttct tcatataaat tagtatggcc
    32641 atcttttcta acagctaaaa ttacagtgcc tccatcaact ataaatctcc atggttgtct
    32701 atttaatgta gatggagcta atcttgcata atgaaatgca tcaagaagtg ctctttcttc
    32761 taaaacttct atgcttgcaa catttcccca ttcgttcata taaacaacat cttctacacc
    32821 tagtctagaa gaacccttat ctgttacaac ttgcatatca gattttgaat aattttgccc
    32881 agtttttgta gcatttaaca ctttagcatt atttacattt tctccatatc caatagctat
    32941 aattcctgtt acctctttat ctgaatcaat tccaagtttt tcttttactt tttttccatc
    33001 ttcaaaagta acccaacaag aaccaattcc tagttctgtt actttaaaga ttatattttc
    33061 tcctatgtac cccgaatttt caatataatt atcttttaca tcagataata ttataatata
    33121 acttggagaa tctatcatat ttcctttgta tcctgctact ttttctaaat tattaaagac
    33181 ttcacttcta ttcataattc ttatatcaac atctatttct ggaactagtt tcttacaaga
    33241 ttctgagtat ttcttaattt cactaagata ttcctcttta atatctgtgt tcttatattc
    33301 tctaacagac tttctattta atataattgt tttataatcc ataattttat cctccccaat
    33361 ctagtcttgt tttaattata tacccattaa tatattattt tactcattta tttaataaat
    33421 aatgattaca attttgtaat tattatttat caataacatt ccacttttac attaataatg
    33481 accagttgtg taaaatccat tgccaaccac caaataaaaa catattataa aggtaatata
    33541 aaataacaaa caaatcttaa caaaaaatta aacttttttt acacgaaaga aggcttcccg
    33601 ttgccttctt tatttttata aaaaaataag ctgtttctaa aatgatttca catttttgaa
    33661 acagccaagt tattctataa tgacaactat aatttgagga tgtgagggag agttgtcatt
    33721 ataaatttag ggtaattata ttatgtttta agctagttct ttctatattt atataataca
    33781 ttttatatat gaattttata tgagattggt ataaatgata tatgaaatta catatgatta
    33841 cattatatta aattttatta ttacattttc cacaacaata ctcatatgtc tccacattat
    33901 tcggaatatt tacaaacaca aattctttac agttctcaca atactttaat atagatatag
    33961 ttccacaagt gtaacattca aatattacac aatcctcatg ttcctctact atttcaaact
    34021 ttttactatg ttcaccacac tctgggcact tgtgattatt tacattcata aatactcctc
    34081 cttattggta tagttacatg tcaaaaactt aattaatgta ttctatatta cttattatat
    34141 attctataat aaatcatatt ctaatataat aaaacaaatt aaataaaaaa aaaccataaa
    34201 ttttaaattt atggattaat tcttgtaatg ataactctat ttgaggatgt gagggagggt
    34261 tatcattaca atagggtatt atattatggt ttttaagcta gtctttctac acttcatata
    34321 atacatatgc tatatgaatt ttatatgatt tttacataaa tattttatga aatttaaatt
    34381 ttttagtcat tttgaaattt gtaaaaagtt ctctaaaaat ccacagcata ataaatagcc
    34441 aaaatttaag taaaacatca taaaaaaatt tgtccaataa ttttaacaag tcacctcacc
    34501 tcattataat tattgacaca aacttaaata aacaatctat aaaccttcta caaaatttaa
    34561 attttcctct tattgataca caatctctag tttgtcaatt ttattttgca tctctaagaa
    34621 aatttcttca acagaattgt taaatatatt gcctaaatag actcttttat ctttttgaaa
    34681 tgaataagat tttacattac cattagaaga aatatataaa tgactccact ctgctccata
    34741 ttttgaaaat ctctcctttg tatctttaaa cctcatatct tctattttta ttgctttttc
    34801 tctgtctctt cttactacag tatgacccct ttttattaaa ctagttattt ttatatcttc
    34861 ttttaatttt atacgtgtat catcatttct tgaatatact ttccatatca ctttatgacg
    34921 ataattatct aattccttta ttaaacttct atcaatagta aagctatctt tagttaccac
    34981 aattaaatca aaatggtcta acatatattg aaatacatct ctcatacctt tattttttaa
    35041 aatatcctca ccaataacct ctataaatct acagcctttc tcatacatac actttaataa
    35101 acttgtgatt tcagaaaaat aattatttgt attattatct gcatctattt ctagagtaaa
    35161 gtacaaagga gtaatgtatg atttgtttcc tgttatctca aatacacttg atactgtttg
    35221 tatattatct tcaaaggtta agtatacatt ctcataaaac ataaaaaatt ccataacttt
    35281 ttctctcata ttagggatat tcctatatct attggataat atatttatta tgtcgtcagt
    35341 agtatttttc ccatcacatt cagccagtac aacaatttgc ttccaactta agatatccac
    35401 atttccgata ctttttttat atccatcttc ttcatcataa ataggaccaa ttataatgtt
    35461 ttcttttggc cacagatgaa ccctagttcc atcttttaat ttcggatatt tatttcttac
    35521 agactcataa aatctacttg tatcacccat tattctttac taccccccat attttaaata
    35581 ttctatgcta aaaatagcac tttattttta ttaattcaac aattattcaa aattggttat
    35641 taaatatgtt taaatggatt taacatcaac cttatttata tgttattgat gttcatatat
    35701 gttatataaa agcttatttc ttagacttca atgtaatttt aactatttct ggcttacaat
    35761 taagcctaat taaaactttt gagcccccta agcctttatt taaaatcata gtgctattat
    35821 ctttttcata tctgccccaa tcatacttag gaaaaaactc tctatttgga gataacacac
    35881 ctccaacaaa aggcattctt attatacctc catgaacatg tcctgctaaa accaaatctg
    35941 ctccccattt tgcatatttt tcaaagaaaa atggcgtatg tgctagaaga atattatact
    36001 cattttcatt tactttacct agattacttt ctacaaaatt gtcacttagt tctaactttt
    36061 tattattagc aaaaaaatat ggataacatt ccaatgggac aattaaacca tataaattaa
    36121 gatgactatt ccctttatat attcttacag attcattttc cagatttatt attttctttg
    36181 aatatagttc cttaaaataa tctttatata gatgtttata tttttttatt aaagattttt
    36241 gttcatgatt tccaattata tggtatactt catatttttc aaccaaatta tctattaaat
    36301 ctaatgcaac ttgaaaattt ttattttctc catctactaa atctcctgtt ataaatataa
    36361 catctggatt taatgattta attttatcca tcaacacctt attgttttta tcaaatacct
    36421 tattatgtaa atcgctcact tgaactattt taaagttatc aaattccact ggaatttttt
    36481 tgttgaaaat agtatattct gtcgtttcta tatgctgagt ttcgtactta tacagaatat
    36541 acaataatat taatactagt actgtcattg aaacctttat aatcatattc tcttcctctt
    36601 tattctattt tattaatatt attataatgc ttttatgttt tttttaaaac aataacatca
    36661 tcacatacat ataaatcttt tcgacattat aaaaataagt tatccttttc taaaattttc
    36721 atttatttta gaaaagaata actataaaat tatctataaa cctctatatt gtgaaatata
    36781 gtttttcctt tatttaaatt tttatatata tgctctaaag ttccatcaaa cctaatagaa
    36841 tgcccagact ctaaaatata agttttccca tccacattaa ggtcaagttt accttctatt
    36901 actagcacat actcttccaa aacatgacta tgtgtagatg aaacatgagt acagttttct
    36961 tcaagctcaa ttataaaaag ttcaaacctt ctttgagggc taaaagggta tattggatat
    37021 agtttcatat tcccttgttg ctcaacaata ggctctactt cttctttttt tataacctca
    37081 taagtatttg tattttcatt taatagtgta gtaaaattta ttttaaatcc agatgaaatt
    37141 ttccataagg tggatactgt tggacttgat tcacctctct caatctgtcc aagcattgct
    37201 ttactgacac ctgtcatctt tgaagcttta tctaaactta tgcccatttc ttgtctcaat
    37261 aatcttaaat tttctcccac attaggaaat ttattatcca tgttaaaatc ctcctgatag
    37321 ctatttgtat tctatgattt ttacccctgt aagttctact atctctttta attttaacat
    37381 atgattgtta caaatttcat caaattcata tatataatct tcaagtccta atgccttata
    37441 tttatcgatt ccaaatttat gatatggaag taattccatc tttccttctg gaacattctg
    37501 cttcacaaat aatgcagtat ttcttatgtt ttcttcacta tcatttactc cataaataat
    37561 tggcactctt ataaccatag atttattcaa ttttgaaagt ctacatatat tatctaatat
    37621 aattttatta cttactcctg tatattcttt atgaatatta tcatccatgg attttatatc
    37681 tacaaatatg tggtctattt tatcaaatac atcatttacc ttattccaat caaaatatcc
    37741 acaagtttca attgcaatat ttatgccttt attataaaaa atatcaacta attctcttaa
    37801 aaaatcaatc tgaagtgtag gctcacctcc agaaaaagtt atccctccat tagattcaaa
    37861 gaaaaatata aaatcttttt caacttcctt tactatttct tcaacactca tttcttcggt
    37921 cattatacaa atagcatctt taagacatgc tttgatacac tctccacata aatcacattt
    37981 attatttatt tgtgttctat caaacagtga acttatattt tgaggacaaa catctacaca
    38041 tctattacaa gatatacatt tatctttcat aacacctaat ttcactatat tactccatga
    38101 atctggattg gaacaccact tacattttaa tttacatcct tctaaaaata tagtagtcct
    38161 tattccatct ccatcattta ctgaaaaatg ttgcactttt acaactctac cttttttact
    38221 cataatctac ctcataatta aaaattacta tgtgaatttc tagctattat agcatcttgc
    38281 atttctcttg ataaattaac aaattgagta ctatatccag caactctcac taataaatct
    38341 ttatattctt ctggattttc ttgagctttt aatagagtat catttgatat cgtattaaat
    38401 tgtacatgaa atcctcctaa ggcaaaatat gatttaacca tagatgttag atttctaagt
    38461 cctctttctg tttccaccaa gtcttgattc agtcttaaat ttagaagtgt tccaccagta
    38521 tgaacatcat gatttatttt tgatgcagat ttcatagctg ctagtggact tgttgtatca
    38581 gtaccaacaa atggagaaac tccctctgtc aaaggttttg ttgcttttct tccgcaagga
    38641 gttgcaccta cgatttttcc agttggtaca tagtttgata tacccataaa tgcactatta
    38701 aatttagaac caaaaatatc cttgtatttt ctagtttcag tataataaaa atcagaaact
    38761 tcaattgcta atgaatctac ataatcatta tcatttccat acttaggaac atctaacgca
    38821 agttttctta actcttcata accttcccaa tcattattta gtgctttggt taattcttcc
    38881 aatgtagtaa ccttatcttc aaatactaat ttttttatag ctgccaatga atttgaaact
    38941 acacctaatc ctataccagt taatacaggt cctatattat attttgctcc tcctttgctt
    39001 aaatcgaccc ccttatctaa acatccatct acacaagtag ataaaaatgg tcttggtacc
    39061 atttctttat gaatttgttg agcaacagta gttcctataa cagaattttt tacaagatat
    39121 gctaattgat ttaaaaactc atccttaagt tcttcaaaag aagtaaattc tgtgatattt
    39181 tttgtatcta gacccatttt ttctccagtt aacctactct taccttcatt catagcatat
    39241 tctaaagctg ctgcaaaatt gatatttacg gctgaagtcc actgtcctgt ttttctaaaa
    39301 tgaggaacta cacatccaca gttactccaa tctctagcgt cttctgcatc atatccatct
    39361 tgtagtaaca tttgtgcccc tgcattatcg ctgtgtatag cagggaagcc agttccttgt
    39421 tttactaatt tagcaactgc catgacaaaa ttatctggtg ctccttgact caccctaaca
    39481 cttaatcctg gctggtgagt ttttacactt tctgtagcct ttaaacacat atatgagata
    39541 tcattcgtcc catcagtacc atttctcttt ttaccaccaa cagtaagatt ttgaaattga
    39601 ttatatcctg caaaataatt tgccgtattt gctgatatag tccataccca ttctgataac
    39661 ttaatccaaa gtgcttctat caattcttga gcttctgatt cagttatttt gccttctcta
    39721 gcgtcgtttt cataatacgg atacatatat tgatcaaatc tacctaaatt taatgccaat
    39781 ggattttctg atagaatacc acctagttga acaaaccata caaattgtat tgcttcataa
    39841 aaattagttg gagggtttgc tggtacattc atacatatct ctgaaatttt tataagttct
    39901 aactttctct ttttgtctgt ttcttgttca ctcatctctt ttgcaagatt tgaatatctt
    39961 tgtgccaatg tcataatacc ctgtgcaact atagaaacag acttataaaa gtctattttt
    40021 tcaatatttt ctgaaatcga tatatctaat tctttaattt ttttatctgc atcttcctta
    40081 atccctttat atccttttac aaacagtata tcttgataat ctggtgttac ctcaccaact
    40141 gcctgtctcc acttagaatc attatctatt attcctgtat ctactaatac cttagctgta
    40201 tcttctggga ttcttgctaa aaaaacttct tccaaagatt ttcccttcca atatggaaat
    40261 atttcttttc ttataaattc tatttgttct tttgatatta catatgggtc ttgagttctt
    40321 tcatcaaaag tatccatttc tttgtctacc cattgccaag aaaactctgg tgttaatatc
    40381 cctgttcttc taaattttcc tgctgtacct actattaatt cattttcaaa gatttttata
    40441 ggaagctctt tacatgtctc caaaaaagct ttagctcttc ttatacagat agcttctccc
    40501 tcagtttttt tatgtgattc agtaaaaatc ctagctcttt cacaacatat cataggttta
    40561 gaattaatat attcttgtct aaatgcttct attctattag tttgactcat ttaaaatccc
    40621 cctttggata aatatatact tatatctttg tatgttataa catactttaa ttatattata
    40681 ctgtccttta gcataaaatg gaagcaaaat aatttatttt ttcatctacc ttgaacacct
    40741 atatattaat actttttttg ctaaatttgt aaaatctaaa aaatttgtct atgatatatt
    40801 ttttatattg ttatagttat ttctagtata ctaacgattt gaaatatcaa atttatataa
    40861 taggcttagt tttaaaactt tagttgattg tttaattttg ttaacttcaa catgtatatc
    40921 tttcatataa ggaagctcta caacacctac tcccttatta aagtcttctt caaccataga
    40981 aaaaatttct ttctcagtta agttcgtatt agtcaatgac ttaaataaat tatatataaa
    41041 tttaatatat ttatcactct cagataactt ctcatcttct ggatactctt tagcacagag
    41101 aatatctatt gttacttttc cttctttatc atcttcagat acagaataga ataaacttct
    41161 aatattttct tcaggtggtt tttcaacact atttatagac actacaaagc taccatctga
    41221 ttttgaatta gtaatactat aaccactgtc tattatggct ttcgaaaatc tttgagataa
    41281 atcttttttt acttcttctc tacctttcac atcattcatc ttttgcgagt aattattaaa
    41341 taactcaata gattcatctt ttttatcttc aactgattct tttaatgaat ctttactaat
    41401 ttgttttgaa ctacttaagt tcttatcaga tacaggagac ttacatccta ccatcaatgc
    41461 taaactaaga tttaaagcca caactattgc cactttattt atatttctct ttactttcat
    41521 acacaatcct cccatcagac taacctctct aaaacattat tcattgtatt agaatatgtt
    41581 tatattctct ttatattaaa aatttattac tcaacacata tcaccttcct atctaattct
    41641 tatagattac tattagtaaa attataaatt ccttaataca aaaataagga tgttatcttt
    41701 tgttattaaa agataacatc cttgtttttt tgtatcaata catatgtccc aactagtaac
    41761 ttaatcgctc caactgtcag tatcttggtc caatggtatg tatatattta gtataaattt
    41821 atccatacta ttttcaaatg ataattctcc attatatttt tgtaaagaag atttaatact
    41881 ttgaatacct attccgtgca caaacttatc cattttgttt gttaacaata tatttttatt
    41941 gaaagtaatc ttatttagtt tactattttc acatttaagt acaaaaaatg actttgttat
    42001 agttccttta attctaatat atttattaat attttcatcc aatattttat cacatgcttc
    42061 tattgcatta tccaaaacat tagagaatat acttgaaaca tctataggtt ttacaaaatt
    42121 tacttttgaa aaatttatag agcaaataaa tttaattccc ttttttaaac atatttcact
    42181 cttttcattg attataatgt ctaatatcat atttcctgta ttataaatat atttaaatgc
    42241 ttttatttca tcttttaaac tgttaacata ttcgtcaatt tctttgctat tatttctaag
    42301 cttgtctata caataaatgt gattatttat atcatgatat agtttcttaa ctcgcatatg
    42361 agattcttga atacttaaat aatgtgcata ttgcatatct aacttatttt ttattaattc
    42421 agcttgagat tttaatctat tttcttttat tatttcttta aacaatagta taagaaatat
    42481 actactagct cctaccaatt tgggattcac aaaattatca aaatagtatc cttctgaatg
    42541 taatgaccca aaccgttcta atttttttaa tacataattt acaagcatat tcattgtatt
    42601 agctaataag gcaaataata aatatacata atttctctta tcttgactaa ttaattttat
    42661 agacttccta aaaaagctaa atataagata tataagaata attattaaat tactatatat
    42721 ctgaattttt atagattcta agtgaggtat taataaggat tctttagatg aaataacatt
    42781 acctgtaatt gcaaaaaata gtattctata tataacagca tccaaacatt cataatatac
    42841 actaaataga taaaagaaaa cagaatactt aatataacct atcttataaa aataattata
    42901 gtatcctccc caagcaataa atgctaatat ataaaataaa tagtttatat tactaaagta
    42961 atttcctcca ttaaataatc tacttatctg aactataatg taaataagaa acaaaacaat
    43021 ataaaatact attttttcat tttttttact atccttttta taaattaaaa ttccgttcat
    43081 tatagaaaac tgtataaata tagataaaac tactaatagc tcagtcataa aatttagcat
    43141 attgtatcac caagaaattt taaaaatttc tccttaactt ctttatatct atatctacta
    43201 ataggtacct cttctccact ttccaatatc acagtattag gctttatatt ttcaacatat
    43261 cttaaattta ctataaaact tttatggcat cttataaatt tatatggatt taattctttt
    43321 tctattttac ttaaactata ttttatatca aaattcttat ttattgtgtg tattagcata
    43381 tctttttttt gaacttctat atattttatt tcatttaaat aaatcttata tgtattagac
    43441 ttatttttta ttgtaatatg acttttctta tttatttcaa tatctttgat acaagttaac
    43501 acatgttttt ttagatcttc tagctctatt ggctttagta aatacctata agctcttacc
    43561 tcatatcctt cttgcacata atctattaat gaagttataa atattatttc catttcatta
    43621 tctacttctc taatctttct tgcagtatcc attccattta gtttttccat ttttatatca
    43681 agaagtaata tatctatatc ttttaaatta ctttccaata gatcttctcc agatagatac
    43741 ttttgtatct catattctat atttatatct tctaatatat tctcaaggta atcttctatt
    43801 aaaagttgtg tttctttttc atcttcacaa actgctatct taatcataaa atgcctcctt
    43861 acataatttc tagttaatac aattaaaatt tttataatat atttaaagat aattttgtat
    43921 atctgatact ttaggataac attttcaaat tatttttatc aatactcaat cctatacaac
    43981 tgttattttg atatctcaat ttaaagacag aaattactat aattaaaaac agtacttact
    44041 gataaaagaa gatgtcttaa aatatcaaaa aaataatttt aggacacctt cttttattta
    44101 aactttttaa gccttaaata atacattaat ctcctatata attgtactgc atataaaatc
    44161 aacaatataa tctgtagtac aatagcagtt acagatgctc cacaaccact atataaattt
    44221 cttatttcaa tattcaataa atatataaat attactacta acataaagaa tataaacata
    44281 ttcataaata aaattgactt tactttattt tttttatcag aatcactata taatttagga
    44341 ggtatgtctt tgtattcttt cgaccatata taccatgcag atgtacccat aaaactgcca
    44401 atactcctaa acacaagatt ccagccattt gatttatgtt catcaaaata attattctct
    44461 gcatcatagt agtaatcaac agtgtatttt atttttcttg gactttcctt atgaaaataa
    44521 aatattcctc caaatttatt tatcctatat aaattatatc ctttagcttc aatatcttct
    44581 aaccatttct ctatcttatc aggtgaacta taccagtcaa atttgaattt tattttcttt
    44641 tccataacac tcattctcca aaatgatatt tttaaatagc ttaaaaatct atttaaataa
    44701 ttatatcatt ttgatactaa ttttaggtta caatcagata tttaaaaagc tatttaaata
    44761 gtaataaact aatggccata acgcccattc ctgcaatcaa tccataaatg gataaatgat
    44821 gttccccgta ctctctagct gatggtaata attcatctag tgatatgaat accataattc
    44881 ctcctacaat tgcaaataca attcccagag ttatatcatt caaaaaattt ctaagaagta
    44941 catatccaat gatcgctcct aaaggctcag acataccaga taaaaaggaa taataaaaag
    45001 ctttcttttt atctcctgtg gcataataaa ctggtacaga tacagatata ccttctggta
    45061 tattgtgtat tgcaattgca attgctatcg gtatagctat tgtaacatca tcaagagctg
    45121 atataaatgt agctaatcct tcaggaaaat tgtgaattgc tatagccatt gctgtaaata
    45181 cacctgttct caaaagagac ttattttttt tgatattctt ttcttctata ttctccattt
    45241 tctttatttc atgtggattt tcttcttgtg gaattagctt atcaataaca gcaatgatag
    45301 ccatacctat aaaaaaagct attacagttg accaacctcc caatttttct cccatagatt
    45361 ttgtcaaagc atcttgtgct ttaggaaaaa tttctatcat agaaacataa atcataacac
    45421 cagcagaaaa tcctaagctt atagaaagaa acttcgtatt tgttttttta gcaaaaaatg
    45481 ctatacaact tcctatacca gtagataaac cagccaataa tgttatcaaa aatgcaaata
    45541 ttacattatt caaataaatc accttctttt taattgatat tgattatcat ttcatttatg
    45601 ctatcatata tattttatat agtcaatatt tatcaaaaat atacacaata aaaaagcaga
    45661 gatataacct tagtctctgc tttttcttca tagtatatta aaattattta ttcaagaaat
    45721 ccactgcata ttgcacatat aaagcagttc caatttctag ggcatcttca tctatattaa
    45781 aacatccatg atgatgagga taacaagcac cttttgattc atttctagct cctacaaatg
    45841 ctagtgcacc aggagctata ttcataaact cagctaaatc ttctgctcct gttacttttt
    45901 caaatagtgt tatacagtct tctccaaata gcttaattgc tgcttctgta gctatctttg
    45961 aacattcttt gtcatttata actgctggtg ttaaataacc atattctaat tcagcttctg
    46021 ctctatatgc tcctgctgta gattttgcta tacgttctaa aattccagga attttctttc
    46081 taagctctgg attaaatagt cttattgtac cttctaagac agcttcactc gcaattacgt
    46141 taaatctagt tccagaattt aaaactccaa cactcacaac caatggttcc agaggactta
    46201 cttctctact aaccatagat tgcaaattca taactattgc tgaacttgca agcactgcat
    46261 caactccttg atgaggaagt gaaccatgac cacctctacc ttttacagta attttaaaga
    46321 aatcagcaga agccattctt ggtccttctt ctactgatat agttccagat tctacatcag
    46381 tccaaagatg tattccaaac acactatcta caccttccat agcaccatct tgaatcatag
    46441 ctcttgcacc tttgccaact tcttctcctg gctgaaaaaa taattttaca gttccattga
    46501 tactatcttt aatatcattt aacacttttg ctgcccctag aagcattgat gtgtgaccat
    46561 catgaccaca agcatgcata agtccttcat ttttagattt gtattctact tcagtacatt
    46621 ctacaacttg taaggcatcc atatcacctc taagtgctac agtctttcct gaattagccc
    46681 cttttatcgt tgcaattaca cctgtacctc cagctgatac atatggtatt cccattttat
    46741 caagttcttc tttaaccctc tttgatgttc taacttcttc catacttttc tcaggatttt
    46801 catgaaattc ccttctaagc ttaattacat agtctttata actctttgtt atttctttaa
    46861 tatccattac agacctccaa gtagtacaca ttcttcttat ttaaaatatt ttttattagt
    46921 taaatactat attagattta caaagatacc cgctattact acagaagcta ttgtaactgt
    46981 agtaaatcca ccaacaagca tctttggaag cattttatcc attaaaaatt ctttttcttc
    47041 tggtgtttca gccagagcct ttactgcttc ttcagttaat atatagtttg gcggaaaacc
    47101 gtaaagtgat gtaagtgaaa ctgaaaaagc catttctttg ctttcaccta aaagctttcc
    47161 tgctataata gaaaaaattc ccatacctat tacaccaaat attatgattc ctacaagagg
    47221 aactgccatt tcaacaagca ttgctggtgt agcttttgct aaccctgcaa atataaaagc
    47281 catcaatgat gtcattaacc atccaaatga accagattta ttaagtggtt ttctatcaac
    47341 tattccaagt tctgatgcta ttacaccaaa tattaaacac ataacatatc ttgatacaac
    47401 ttcatttgta agatttgtaa attgtactgc taaccatgct acaaacccta atctaagtat
    47461 tatcatatat gtcgtatcat atttttctgg taagtctgga attatcttaa atctgctttt
    47521 ttgttcaggt aaatccttaa ctttttcttc agctgtattt acagttactt ttccacttct
    47581 aaaatccgat aaaagtcttt ttccttcttt tttaagcatt aatgctgtaa taggataacc
    47641 tgcaaatcct tgtgcaacat acattaaaat tgcaagtact gacaaacttg caagaccttt
    47701 tgcagtagca gcatctgcca tcattataga tgcaactagc cctccagtaa gaggaggtgt
    47761 agctattact gctgtatccc atccaaatac tactgtcccc aatgccaaag cacctacaca
    47821 tattcctact attcctgcca aggctattac gattgttttc cattgacctg ctaattcctt
    47881 aatactcatc atagttccca tatgagttat taacaaaagc atacctaatt gagctagtgg
    47941 tgttcccaaa gcggctaagt ccacaatatt ttctgggaaa aaagtccaaa atcctactat
    48001 aaatataatt gctgatacaa aaaccgacgg aacaaaagct ttagtttttg ctgaaactac
    48061 atctcctatc gtcagagata ttaaaactaa acaaaaagct gttattgcct ccatacaaaa
    48121 tcccccctca taataaatgt atttttataa aatgtatgta tagttatcca ttattttact
    48181 acttttgaaa aacatttcaa gtcaaatttc gttttttttc ataaaattct ataaattcta
    48241 caaattaaag ttagttttct aaattattct ttttataaaa acgttatccc tcggattggc
    48301 tattttactc tatttttaca aggagaatta agtgtaattt tcaaaaaata aaacatagaa
    48361 catattttat tcataaaacc ttccattaat ataaaatgaa ttgtttttat gaatcttaat
    48421 atatcctatg tttgtaagtt taatgcgtat gttagctata gtgtaaaact tatatactag
    48481 ttattgtgta acctactata tactccattt ttgtttacta actcttcatg agtacctctt
    48541 tcttcaattc ctttatctgt caatactatg atttcgtcag cattttttat agtagtcaat
    48601 ctatgtgcaa caactaaatt tgttctatct ttacttaatt cttctaaaga ctcttgaatt
    48661 tctctttctg tgacattatc taaagcagat gtagcctcat ccaatattat tattggagga
    48721 ttctttaaaa agattcttga aattgaaatt ctttgttttt gtccacccga taattttact
    48781 cctctttctc ctatataagt atcatatcct tctggtaaag tctctacaaa gtcatgtatc
    48841 ctagcttttt tagcagcagc tatcatttct tcatcagttg cattagggtt cccacaaaga
    48901 atattatctc ttatagttcc tgtaaataaa aatacatcct gttgaactat acctatattt
    48961 tttctcaatg attttaaact gacatctctt atactctttc catctatttt tatatcaccc
    49021 ttatcaaatt cataaaatct tggcaacaaa ttacacaatg tagtctttcc tcctccagaa
    49081 ggtccaacta atgctatagt cttaccagct tttatagata agctcaaatt atctaaaact
    49141 tgagtcttat cttcatatgt gaaagatata ttttctatct caatatcacc ttttacattt
    49201 tcaagttcaa tagggttttt agcttctttt tgatggtctt gttccattat ctctataaat
    49261 cttttaaaac ctgtcatacc attttgatat tgctctgtaa agtttattaa ttttttcata
    49321 ggttgtataa acatttttac atatagtata taagcagcaa aatcacccaa agtaattttt
    49381 cctatataag taaagtaacc acctgctatt acaactaccc actctaagat atccatgtac
    49441 aaattcatac cagagtagta ttctgccatt actttataag aatcttgtct tgctcttcta
    49501 aataatttat tgcttcttac aaacttattt aactcttctt tctcagtaca aaaagactta
    49561 gttactttca tacctgctat actattttct aaagtagcat ttacatcacc tatagtgact
    49621 ctactcttca taaaagcaat attcatctta tcttttttag ctattgcaaa ccaaattata
    49681 aatggtaata tagcaaatat tataagcgta agaggaatat ttatatctat aagtataaag
    49741 aatgaaccaa ccaacattac tatagagatg aataaatctt caggtccatg atgtgcaagt
    49801 tctgttatat ccattaagtc atttactatt ctagacatag ttactccaga tttgttatta
    49861 tcaaaatacg tatttggaag tctttgtaag tgtgtaaata cttcatttct catatcagct
    49921 tgcatatcta caccaataac atgtccccaa tactgcataa aatagttaag ccctgctttt
    49981 gctataaata taagtataag tgctactgca aaaaccacta acattcttaa gtttttattt
    50041 ggaacaacgt catccattat atttctagtt atcataggat aaactaaatc acataaggaa
    50101 aataaaaaag ctgctataag gtctagtgta aaaattttct tatatggctt ataatatttg
    50161 acaaattgtt ttatcataag tattaaatcc ctcctttatt agtacttcta aaaaataccc
    50221 ataaattagt ataacataac aataacttta aatcttttat aaacttataa atgaaaacaa
    50281 tatttttcat aaaattgaat atttatcata tagttgtatg cttgaaataa cataaaaaga
    50341 gctatatctc tataaataaa aatttataaa gatacaactc tatatttaat actgaacttt
    50401 ttttataaat acaaaactac ttcaatgcat tcaatatttt tttatccaat gccgttgtat
    50461 ttatacctgt tatatatcct gttgccttta ttgtaggtat atcataagtt gttggtagta
    50521 tagtagtaga tacgattaaa tcagcacctt cttgttttgt tgaacattca gcaattttac
    50581 attgctcaat ttctgcttgt atattatttt ctttaaccaa cctttctact ctgtcacaaa
    50641 ctattgttga tgttgcgatt cctgccccac atgctactaa tatttttttc atatattgtc
    50701 ctcctacact ttcttcaata ttttataatt taaaatacaa ctgataaatt tcctatatct
    50761 ttatctatat aaataattat atcattttat atcaaaagaa catcttaaaa ttattctttt
    50821 agtatgtttt ttatttcaac attgcttata cttaaaatat cattttttat acaagactct
    50881 atgtactttg atatattttt atagtcattt aaatcaaact gttttatatt caagttatat
    50941 tttatatcac taacaatacc taccaaatca gacttattag aaaaaatatc ctcatattta
    51001 tcttttctag ttacttccaa tcttttaaat ctatagtttt tatatccttc tatgataatt
    51061 aagtccatat cttcgtataa ttgaatcatt ttatataatg gactcttatc ttttagttct
    51121 tcaatatatg ctactcgttt atctgatatt atacagactt ttctcgcccc agattttcta
    51181 tgtttgtaag tatcttttcc ttcctcatcc atatcaaaat cgtggcaagt atgtttaata
    51241 actcctacac gatacccttt tttatttaat tcttttatta taccttcaat caatgtagtt
    51301 ttacctactc ctgaatagga gacaactgac aatatattat acataaaatt gtgtcctttc
    51361 ataaaactat ctaataacaa tatcgactaa ttgattttct tttattgttt cattcttttt
    51421 aatcttaatc atacaattac ttcttagagt tgcagataat ctagcttttg catctttctt
    51481 atcatttaac tctacataca atttcccttc acttgtatat agttttccat ttacaaatct
    51541 atctttattt gaaagtttat taaattctcc tttaaatata gcttttatat aatgtattcc
    51601 cttcttatat gttaaatact caataacagg aactaccaca ttatcaaata caatgattgc
    51661 tgcatgtgga ttaccagaaa gaccaaacaa tagcttttct cccaatgtag ctacataaca
    51721 agctccacca ggcttaatgt ttatcttcca aaataattct gttgccccta tttttttgaa
    51781 tacatctgga attaaatctt tatctccaac agagacacca cctgttgtaa ttaaaaaatc
    51841 tgcattctgt aacatatccc ttaccttttt ttctaactcc aatatatcat cagaacaatt
    51901 gcatattgta tctgcttgta ttccaagttt taataatctt gaatataagg tatatctatt
    51961 actatcgtat atcttaccat tctctaaagt ctcatttata tcttgtagtt ctgtgcctgt
    52021 attcaaaatt ccaactttta aatcatcata aacagttact ttggatattc caagacttgc
    52081 taatactcca ataccatcat atcctatatt ctggttttta ttaataatca attgcccctt
    52141 ttttatatcc tcacccttaa atatataatt atcgtattcc tttaatttta catttaaagt
    52201 tatcatatca cctataaccg ttacatcttc tttttttatt acacagtttg caccccttgg
    52261 tatttttcca ccagtcatta tcttcactgc ttcaccttta tttaataccc tgttaaatac
    52321 ttctcctgca tacaaagtcc ctataacctt taaatttcta ttttcagaat ttgcattata
    52381 tgcataacca tcatatggtg acctatcaaa tggaggacta tcaattgttg aatatatatc
    52441 ttctgcaacc actttattta ctgcatctat gagatttact ctcttgaccc tgtttattgg
    52501 taaaacattt ttttcaataa tttttatggc atcttctaat tctatcattt taaatactcc
    52561 ccaatatatt ttttatttaa gatatttcta tgttaatata ttatatatta caaaatttgg
    52621 aaatactttt atcttatctt taattataac taatagttat ctataagtgc agttcaaatt
    52681 ttataaatct aataaaaaaa ctgttcccag ctagaaattt ccttctatct tgaaacagaa
    52741 tcgtatgctt tagaatattt tattctaata aagttccttt tattattttc acaattttat
    52801 cactttcaat agtttttata gattttattt tgttatccac aatacttatt gtaagtacct
    52861 ctttttttaa tattttgtta tcttctttca atctatagct cttaactact ttactacctt
    52921 catgattata tgctgttaaa tcataattcg catctcctac aatttcagtt attctagact
    52981 cttcaacacc aacatactct cccaggtcaa tacgtctaaa attttctagt gatacagccg
    53041 atttttcatg gtcacttttt tcaatcacaa tactagattc agcatcaaca actgcaatac
    53101 cttgtgatga gaaagaatta gtttcaacat tgacaacttt atttccgtta atatcaacat
    53161 ataaagcact tccatctagt tcgtcatttc cagtatattt tggataaact aatgtcatat
    53221 aacttgatgt atttatatct tgcattgtat ttgattcttt taaaacttta ggttttatat
    53281 aataaaatgt attataaggt atacccatat tctttataat atacttataa tctttattca
    53341 taatttcatt aacatcattt tgaacttttg tcatagtttt ttgctgtgtt gctttacttg
    53401 ctacttgatt tttctcttta gtattttctt tatgacatcc aacaagtata atacctaaaa
    53461 tagttacaca aactaatgac ctttttaact tcataaatca atcctccttt cttaaatttt
    53521 atagtattta tctatatatc aatttacagt tatctctttt ttcaataatt atatttatta
    53581 tattataaaa taattatata atatttattt gaatttaata agattaagaa gctaattgta
    53641 atttttctgt aataaaacat actttaaagt tgaattttga aaattcaatt tacgatattt
    53701 ttattattaa gtaccttaca acattatacc aaattattcc taaacaatca aaaactccat
    53761 gaatatttaa aggttttcta ttttaaaaat cacctttgac tattaattta tcaaatatgt
    53821 tataatagtt ttagataatt taaggaggat taaataatgg attttaaaca acttgaagta
    53881 tttgttgctg ttgcaaaaca tcagagtttt tcaaaggctg caagagaact ttttttaact
    53941 caacctactg taagtgcaca catacagaat ttagaaagag agttggaaac tgttcttata
    54001 aatagaagca acaaagttat tacactcaca aaatctggtg aaattcttta tgaacatgct
    54061 atatatatat taaataattg taaacgtgca atttatgata taaaagaata ttcaggaaaa
    54121 atagaaggta ttatagatat agcatgtagt tccatccctg aaacttatat tttacctgat
    54181 tttatgaaga gtttttctat gagttatcca gatgtaaaat tttccataag ccattatgat
    54241 tctcaatatg ctatatcaga aattttaaat gaacgaataa gctttggatt agttggttct
    54301 aaaatcaata atcctcaaat agagtaccta gacttattag atgatgaact tgttcttatc
    54361 actccttcag attttaaaat tgataataaa aataattgta tcgatatagg agaattggct
    54421 tatctgaatt ttattatgag aaaagaaggg tctggtacaa gaaacttaat actaaacaca
    54481 cttagtaaaa ataactttcc agtaaataaa ttaaatgtaa tagctcatgt agaatcaaat
    54541 gaggctatta aggaaatggt taggttaggt cttggagtat cctttatatc gtacatttca
    54601 gctattgatt atctcaatgc aggcaaaata aaatgctata aaataaagga tgttgatttt
    54661 actagaaaat ttttctttat ttactctaaa aagaaaactt tttccccatt agaagataaa
    54721 tttctaaaca gattatgtga gtatttcgaa atcataatat aataacttta ataaaacatt
    54781 gcttaatttt agatttacaa ccaattaata atctaattat aactatcaca taaatactta
    54841 taaattatta taaatcatct ttctttttta tttaatttag tcaaaaaatc cctcattcaa
    54901 atgaacttgg gatttttttg tttatactac tccaatagca gctaatacta tacaaataat
    54961 cataactgaa attagtatcg tagttgtctt tacctttttt cctaataacc aatacataat
    55021 accgaatatc atagctggaa gcatacatgg cattatttgg tctaagtaag tttgaatagg
    55081 ctctgcccat tctccactac ctacattaac actaagtttt aacattacat tagatgcagt
    55141 catacctcca attaccataa gtcctaacat tgaagctgct tccataactt ttgaaactat
    55201 acttgaacca ctcacatctt taaagaattg agttccatac ttaaatcctt tatctagaca
    55261 tatataacgt ataataaaat gaggaacatt tattattaaa aggaacaaaa tcggtcccat
    55321 tatgttgccc tgagaagcta aagctatacc aactccagct gctataagct ttaatgttcc
    55381 ccagaaaaat gaatctccta ttccagaaac tggacccatt aaacttgatt taacagcatt
    55441 tatactatta gcatcaaatt ctttgttctt tgcattttct tcttccatag ctccagatat
    55501 acctaccaaa agagtactta tatgaggagt aactgacata aattctaaat gtctttttaa
    55561 agccttagat ttcttttctt tatcatcttt atacaatcta cgtattattg gtgccatcat
    55621 gtatgcatat gctatatttt gcatacgttc gtaattccaa gatgaatcta atgtcaatga
    55681 ccttctaaaa catttccaaa agtctttcct cgttatttta ctgtctggtg aaattgtctc
    55741 taacttctta gaactcgttg tcatctacta ttacctcctt ctctcctaca aagttaacat
    55801 atattaaggc tattgctaat ccaaacaatg caactcctgt tactgttatg tttaagtaag
    55861 caaccaatat aaatcctaat aataaaaatg ctactgtttt cttattaagc atcattctag
    55921 ctaacatggc aaaacctatt gctggtatca cacctgctgc aacatccatt ccatgagtta
    55981 catatgatgg tatgaatgaa agtattttct ctattactgg aacacctaat gaaaatccta
    56041 ttcctactat tattgctaat atcaatttat ttcctatacc aaataataat tgtatacgct
    56101 ctacaccttc aatattcccc tcttctgcat aacggtcagc aaggtgagct ccccaagtaa
    56161 gtactactgt catcaagaag ttatctataa gcaatactag agttgctata ggaactgcaa
    56221 gtacaactgc tgctgataca tcttgaccag ttaatattac aaatgctgtg gcaataatag
    56281 acccagatac aaaatcagga ggattacttg ctccaacagg aaatgcaccc ataaatacta
    56341 attctaatgt tgaacctatt actatacctg tgtgtaaatt acctagtgct aaaccaacaa
    56401 gtggtgcaac aactataggt ctattatgca ttgtagaacc tacaaaacta tgcatatatg
    56461 caaagaatgc aattagagtt atcaaaataa cttgtgtaaa ttccattttc atccccctaa
    56521 aattatatta atttcattac atttgtagcg tcatcatcag gaactaactg tacaaataca
    56581 tttacgcctt ctgaatctaa ctctttaatc atatttatat catcttttga tacatgtact
    56641 gctttagata tattttcacg attatcatct gattttgttc caccaaggtt tatagattta
    56701 atagctttta cctctttagc aagtctataa acatcttcta cagattcaca aagtatcaat
    56761 aagttatatt tatcagtaac acctgagtta agtgctttta tagaatctgc tatgcttttc
    56821 attactagct taacattaga tggtttagcc attttaagtc ctgccattcg taactcatct
    56881 tttaataatt catcacttgc tattaatata cagtctgtgc ttaaaaactt tgtccacgta
    56941 aatgctactt gtccatgtat aagtctgtgg tctactctta ctaatttaat cattataatt
    57001 cctccctaat ttttttgatt tcatccatga atgtttttac gtgttctaca ctaacatccc
    57061 caaaatcttt gtaattatct ttaaagtaac ttcctattat tgccatatca cctaattcaa
    57121 gctgtttttt tgcattttct aatgtaactc cagcagctat aaccaatggg aaatctccta
    57181 aatttttacg aaacagttct attttttcca ttgatgtttc ttgacctgta gcattttctg
    57241 taactgctat agcatcacac cttgtcattc ctatttttaa atcttcttca atattatttt
    57301 ctgataatac tggttgatat ttaaaacgta cgcctccgat taaatatgct ggacatttcg
    57361 aacgttgtaa tttaaaaaat tcttctaaag tagcctcatc tctaggttta acatgaccta
    57421 ctacagaatc aacctgtata taactggcat tatattttgt tgccagttcg aatcccatag
    57481 tatcaacatt taaacagttt actccatatg gtattgataa attagctttt gatacatact
    57541 caagtattct ttctaaatca taataattac catagtaatt ttctaacatt attccatcta
    57601 caccattttc ttcaaaaatt gcaatctctt ttttagctct ttcaaagata tcttctggag
    57661 tgtctccttt taagtgtatc attgctataa ttggcttttt acttttaaat actgataata
    57721 ttcccttttt tttcataaac taaaatacct cttcttcttc tttaatttgt aatgtcacgc
    57781 tttgtattcc tcttctagat tcttctacta attggtctat atcttcaact gttaattcat
    57841 cagaaaatct tgtaagaagt tctagtacca tattcaaatt cattccagaa aataacttaa
    57901 cattatgtag attagttaat cttaacattg ctgtacatac acttgctcca tataagtcag
    57961 ataaaattat atattcacat tctttatctt ctgatattgt tttttctaat tctaaagcaa
    58021 aatctgaagc actttgtcca gggtataaac catacgaact aacacaatct gctaaatctc
    58081 ctactatcat ttttactgca tttaaaagcc cttttgaaaa gtctccatgg gatgctaata
    58141 ttatcttttt catacttatc ctcctactaa atataaatta tatttctgct gatactgcat
    58201 atttgtactt atcacttctt ataaattgct cattgtaata taatacatca ttattttctg
    58261 tatacaccga ttgtcttact ttcaatagtg gcatattact tgcacattta agatggtcag
    58321 aatattcttt gtttgaatgt tttacctcaa atatattttc tactcgctta ggtaatgtgc
    58381 ttatattatt agatataacc tccattaaag atttatcttc tagttcttct tttaataaaa
    58441 acatataatc tattctaaaa taatcaactt caaaaataac aggtacttca tctattaatc
    58501 taagtctttt gatacatatt accttttctt ctagttcaat acttaaagct tcagctactt
    58561 gcttatcagc tttttttatt aaaacagaga ttattttagt gcttggtttt gcattaatac
    58621 gatgacaaga attagtaaaa ctatttcctg cacatgttgc ttctattctc tctggtattg
    58681 ttacataagt tcctttacca cgttttttac ataatatatc ttcttttaca agttcattga
    58741 gtgcatttct aactgttata cgacttatat taaattcttt acataagtct ccttcagatg
    58801 gaagtttatc tcctggttta tatatgccag atgctatttg tttttttatg ttgtcatata
    58861 gttgttgata taaaggaaca aaggaattta cttctaaatc catttctttt ttttgtctct
    58921 tttcatccat tttgctcacc tccctatgta acatttttat aacattatat aacaagttct
    58981 ttattacata ttataacaag atgaaatcgt tgtcaatttt tttttaaata atttttaatt
    59041 tgacagtatt ttattttatt ttctccagtg tgacatattg ctatttttac aaaaaaataa
    59101 gactgttgta caacaggtta aattgtttat acaacagtct ttattaactt attatgctta
    59161 tatttttact tataaattta tattaaaaaa tgccttatat cccttataca tttcatatat
    59221 gtctacttta gagacaatct catgtggtgc atgcatattt aaaactccaa caccacaatc
    59281 tataacctct gcaccttggt ttgccaatat atgggctata gttccgcctc ctccttggtc
    59341 tacttttcca agttcagcag tttgccatac tacatttcct ttattaaaaa ttctctttac
    59401 ttctgacata aattcagcat tagcatcatt acatccactc tttcctcttg aacctgtata
    59461 cttagttaaa actactccat ttcccatata tgcagaattt ctcttttcat acgcttctcc
    59521 aaaatttggg tcatatccag cagaaacatc agctgataat accttactat ttgctaaagc
    59581 ccttcttact ttaatatcac aataatctcc ttctaaagca atcagttcag ccacagtatt
    59641 ttcaaaaaat tttgagtgca tacctgtatt tcctttagaa ccaatttctt ctttatctac
    59701 acataatgca actgaagtaa actctggttg ttcagtttct aatatagctt ttacagcagc
    59761 atatgaacac accctatcat catgcccata tcccaacacc attgacctat caagccctaa
    59821 atctctagcc ttaccagctg gaactacttc aatttcagca cttaataaat cctcttcaac
    59881 tatattatat ttttcattta aaatctttaa tatatttgct gttataggtt ctttttcttc
    59941 atcatctaaa ggaatattcc caattaatat atttaaagct tctccactaa ttccttctga
    60001 taatttcttt tgcatttggt ctccagccaa atgaatcaat aggtcagtta cacaaaatac
    60061 tgggtcatta tcttcttccc caatagatat ctccactttt gttccatcat ttaatataac
    60121 aattccatgt aaagcaagtg gaacagccgt ccactgatat ttttttattc ctccataata
    60181 gtgggtctta aaaaaaccta gattactctc ttgatacaat ggatttggtt ttaaatctaa
    60241 tcttggtgaa tctatatgac ttcctataat cttcatacct ttttctatat aatttttacc
    60301 tattacaaaa agtgctactg ccttctcttt atttataaca taaatcttat caccacaact
    60361 tatgcttcct ttttccatag cttcatctat tgaaatatag ccattttctt tagccaattt
    60421 tataatttct tttactgaaa gtctttcagt ctttgactta cttaaaaatt ccatataatt
    60481 gcgagaatat tgcataattt gttcaatagt attttctttt ctttcaaaat cccaagcatt
    60541 cttaaattcg tactttaagt tcatactttc ctcctactaa attctaattt ttattgtttt
    60601 tcatgtattg ctcatattct tctggtgaaa ctactttgac actatctagt cttgacctaa
    60661 agtgggctct gaaattttca agatattctt tccttaaaat ttctctttct ttgatttcat
    60721 cagcagaaag gattccctct ttatttttct ttgctaattc attaatccta tctaatttct
    60781 ttttgtcaaa cattttttcc tcctaaaaac ttctatttat ttaataaaat aatttattgc
    60841 tttttatatc taacttgttt ttatattcac aaaaaaactc atctatatta tcacttatta
    60901 tagatattcc cttttctagc tcttccatgc ttggacgagc tatatttatt ctaaaaaatc
    60961 tatcatctac tagattgtca aaaaaataag tccctggaag cattgacaca cctttgttta
    61021 acataaaatt tgtaaatgct tgagatgtat atcctcttgg taattctaaa aaaaagttta
    61081 ttcctccaca agattttcta acttttaatt taccactcaa tttctcatta atcaagtttt
    61141 ttgccaattt atacttatca gtatatatct tctctatatg actcaaataa tttttccaat
    61201 caaaattatt catatagtaa tacattgatt tttgaattaa acctggtgtt gatatatctg
    61261 atgaatattt agcccataaa acttttttta acaactcatt tggcatttct acaattccta
    61321 tcctaagacc tggcataagt atttttgaaa agctttttat atatactact ctatttttat
    61381 catcataact tctaattgtt ctattgtcca ttgattcaaa aacaaaatca cttataaaat
    61441 catcttctat tatataaaaa tcatgttctt ctgccaattc tattaatttc ttttttttat
    61501 atgttgagta agatattccg gttggatttt gaaaattagg cataatgtat ataagtcttg
    61561 gttttatttt ttccaacttt aattttaaaa tacctatatc aattccatca tctagcatag
    61621 gtatagatat tatttttgca cctctgcttt taaacacttc aattgctcca ttataagaag
    61681 gttcttccat aaaaacaaca tctgaataac ttataagacc tttacaaact atgtctatac
    61741 cttgttgagc acctgatatt atttgaatat tttccttagt agtttttata tttccatcac
    61801 ttagatactc caccatcttt tctcttaatt cttcagaacc aagaccttca tcatattcaa
    61861 atattgagct accgtcttta gataatgcca tatttacagc atttttaaat gaatcaatag
    61921 gaaacatatc attagatgga ttcccattgt caaaatgaat taaatcttct ctttgcacaa
    61981 taatcttatt ttttctgtta tctataccgc ttttataaga atttaaacta gatacaaaag
    62041 ttccactccc tataatttta tatacatatc cttcgttttc taaaagttcg tataccttaa
    62101 ctatagtggt gttgtttact tgtaaaaaat ttgatagttt tcttattgga ggcaattttt
    62161 cgtgttcaac taactcttta tttattatca attcttttat atgattaaat atttgtatat
    62221 atttagttga ttttttctca tttaaatcta ttctgtattt ttccaaattt atcaccgctc
    62281 attgtattta tattttattg atgcttttac gtatatttga tattatttag tatgtatata
    62341 taataccaaa atttttataa aaaggggaaa tatttatgtt ttacgactat cacatgcact
    62401 caagtttctc tacagacgga aaatctacaa tggaggaaat ggtaaaaaaa tctattgaac
    62461 ttggtttgga ggaaatttgt ttcacagacc atgttgacta tgatgtatat gctgatgatt
    62521 ccttttcaat tgtctacgaa gattatttta agagtttaga gactcttcaa aacaaatata
    62581 aagataaaat atcaataaaa aaaggaatcg aatttggagt tcaaactcaa ttaatagata
    62641 catacaaaaa ggaagcacat caatatccat tggactttat aatatgttct atccatgcta
    62701 tagatacaat ggacttatac cttggtaatt attttaaaga taagactcaa cacgaagttt
    62761 acgaaaatta ctacctttat ttatataata ttgttaagaa ttataaagat tactctgtct
    62821 taggtcattt agatttgatt aaaaggtatg caccttatga cactatttta gatgatagat
    62881 tattttctga tataattgaa gaaaccctta gacaagctat ttatgatggc aaaggtatcg
    62941 agataaatac ctcttgttat agatataatc ttccagacct aaccccatct aagtatatcc
    63001 ttcaaatgta caaagacttg ggaggggaaa tcataactac aggttcagat tcacatcata
    63061 taagtcaagt tgcatgtgag tttgactaca tatattcatt actaaaaaat atgggattta
    63121 aatatgtatc taaatttaat aaattgaaac cagaatttat aaaattataa atttttacac
    63181 ctccttgtga atatatttaa aagataagga ggtgattttt tgaaagtacc ttatttagta
    63241 ctatcaacag ttattttatt tatatccaat tttattgtaa gaatatttgg ttttttatat
    63301 aaaatattct tatcaagagc actaggtgaa acaggtctag gtatctatca tatgattttt
    63361 aactttttga tgatttgctt agctgttaca acaacaggta tacctactgc acttagttgt
    63421 ctagttgcaa aaagaaaagc tttaaatgat agacacaata ctaatgcttt atttatatca
    63481 actttatata tatcattttt cgtagcacta actatatcta tagttgcatc tttcaacagt
    63541 tcttttttat caattaagtt tttaaaagat gctaaattaa acctatttat actagctgtt
    63601 tgtcctgcta tagttataat aactatttca aatgtactaa gaggatatta ctatggcata
    63661 aagaatgtaa aaatccctgc tattggacaa atcattgaac aaattggtaa aatattattt
    63721 gtttttttac ttgttatgta cataaataat aaatctatga attgttatat agccctatta
    63781 ggtatatcaa ttggtgagtt gagcaacatt atatttatgc ttatttgctt atggcgagat
    63841 tcatcatttg acaataggta tattataagc ataaaagatt tttataattc ttctatggaa
    63901 acattaaaaa tgtccattcc cataacttgt aatagaatgt caaacatact tttgcaatct
    63961 ataagttcta tgatgatacc atcaagatta gcattatcag gaatgactta tcaacaatct
    64021 ttaagtatgt atggcgtcat cagtggtatg gtaatgcctt ttatattttt accttttact
    64081 gttggttcag cgcttattgt aaatttaata ccaactattt cacaggaaat ggctctaaga
    64141 aagcgtaaga gtgtaattaa aaaaatcaaa tactcaatac ttcttacttt atttgtaggc
    64201 atactatcat caatattttt ttatttcttt ggaaaagatt tatgtatatt agtatttaaa
    64261 aatacacttg caggagaata tctaaaagct atgtttttag ttccactatt tatgtcacta
    64321 aatcaaactc tatctggcat tttacattca ataagaaaag aattagcttc aagtataaat
    64381 actatcactg gtatgttaat tcaactgata gctttatatg tatttcttcc aattccagga
    64441 cttaatattt atgcatatat atacacaatg acgatagtat caatctttac ttgtctatta
    64501 catactatag tgctttttaa atcactaaaa gctatacact agttataaaa acgtgaaggc
    64561 taccaatgta aattatacat tttggtagcc ttccttagat gatttttatt tataatttaa
    64621 actgtctata tctctaccta tctatctgtg gcaacttggc tttccacttt catgattagg
    64681 tccacattgc gaaaaatcac atactttaga gaaagtatca acaagtcttg gttggattgg
    64741 atttggtgat gctaaaacta ctatttgttc acttattaat gtgctaactg tattttgtaa
    64801 gcaaagtact aaatctatat catttggtat tattaattca tagaaaggtt cacaacattc
    64861 gttacattct aattttaata tagattttcc tatacaatct acagttaagt tagtttgata
    64921 ttcttgtctt aaagtaacag ctcttccgtc agctggcaag catattggtg ctgaaagtgt
    64981 gttaaaagta aattctacat aatcaactct tctcttacat ccacctcctg ctctaactgc
    65041 tgggaaagct aatgcaacga actctgtaca tccacatcta cctcttagct ctagtactaa
    65101 attacgaact gctacagtta atcctctttg tttataagct actgattttc cttttccttg
    65161 tctacagcac tcagcatttc tttctccaca aactgcaaat tcaaaagttg tttcacagtt
    65221 tcttcctact atatctccta atgggtctaa atcgaaatct tctaaagttg tcattcctgt
    65281 atctataact attccatcat tacttaaaca tattttttct atagttacac ttgctttacc
    65341 tgcacttgga actgaaccaa atacttctac tacttctgtt tcaaaagtta atggctctcc
    65401 atttggtcct gttgcatctg taaatgtttg gaattgcata gtatcaaata ttctattagc
    65461 ctctattgca aatggcactg catttgatac agagaagttt cttggagata taggattaca
    65521 gcattctggt ccacatttgt tttcaaaaca ttcatctgaa tccatttcac atggttcaca
    65581 atcacattta caatggtcat ggcatccaca attgtcatca catggattag gtttgcatgg
    65641 gttgcatgga ttaggtttac atgggttaca tggattaggt ttacatggat tacatggttt
    65701 gcaatcatca tgacaatcac atttattatc agtattacat tcattatgat gatgtgattt
    65761 tttaaaccct ctcatatctt ctgaatttat ttcctctgta tacacttctt cttcattcat
    65821 tgtaggcatt ggctgatttg tcattcttct tttatttttt ttataatctt gcatttttta
    65881 ttgccctccc tgtaagcgat tcttattaag tctttggctt tttaaagcct aattaatact
    65941 atgctctttt gagcttaatt gttacttcgc tttttaaatc tatcaataat tagtcagatt
    66001 tagtaaaaaa atgcattttt aataaaaaaa gtactactat ttgaaatagt agcacttttt
    66061 ttgtcccgaa acaccggtgg ctaagtaaat tcacacccta ggcactccca ggtgggtgac
    66121 ttgccagtaa cctttaacgt ccaaactaac taggcatgtt ataatttacc agacacggtc
    66181 tcccgtattt catttgtagg ttgaatttaa aaaagcctta tcgtatgttt caggatttca
    66241 tattattatt atataataaa ttttgaattt tttaaagtgg ttttatatag taattgagat
    66301 aatcttattc tatcattact ttttcttcct tttttcttta tgtatttagt taattatcgt
    66361 tttttcttag ttctggtttt agtatttttt gcattataat tgtattcgga ttcttgctca
    66421 ttaatgttgt atagctcctc atcatatact atatcttcat cattttctat attttcatag
    66481 tctgttttat tatcctcgac taattcatct tcattatcct ccatttcatc ttcgtctgtt
    66541 aactcttcat catcataatc caattctttg tcttcatagt ctaattcctc atcttcatta
    66601 ttcaaccctt cattattgtc ttcatcttca ttattactat catcacctct taaaagactt
    66661 cctaacaatt tgagattatt catactgcca agattgttta tatttgccaa agagcttaaa
    66721 ctaaatccgc cttcaccaaa gtcatctggt aaaaataatt ctgcaaataa atctatcttc
    66781 tttttcattc ctatagcttt ttcaactgaa ttttttcttt tttctgggaa tacatctata
    66841 atttccttta tcatcatatt ctttttatca tcactatcca tttttctgaa aaaatccgtt
    66901 tcatcttcta tatctaccat atctatatta tttaattttt ttattcctct aaccaaatct
    66961 aaaacacttt ctatttttat tagtattttt ctttcatctt ttgacatgta ctttttagtt
    67021 cttgttatta tttccattcc catttctaaa tcttcttcac ttaaatccat gagccttaag
    67081 cctcttttta tgtcatttgc atcaaacctt aaattgctat gtgtagactg tgacagttta
    67141 tcatttgcat tttttttgtt ttttctaact ctattatttc cttttgattt atttttatca
    67201 tcaaatatag agatattacc attactcaat gcaatcactc caatcaaaaa tagtaagtta
    67261 ttcaagacaa ttccccctta tattatataa ttgccctata ttaaagtatg tttttcatat
    67321 tttaatgttc catttttaaa gctcagtgca tatatattat ctataagaat ttttatttat
    67381 attatatatc actcacaatt caccacttca atattatttc tatatataaa tagtatgaat
    67441 ataattcaat atatatttat agaaaggggt ttttttatga aaaaattaga tgcagagtca
    67501 ttagaaaaaa tggctaaaca aaaaaatatt gacaaggata aaatagaaaa gatggctgat
    67561 agttacaaag gaaaatcaga aaatgaactt atggaggaac ttataaaaat aggtaaaaac
    67621 ttagatggaa gagatgaagt agtatcaaaa ttcaaagcgt ttttagatga aaatcaacgc
    67681 aaaaaattgg atactataat ggaaaaaatc tcagatgcag aaactcagag agatactaaa
    67741 ccagctaaaa ctaagaaaac taaacctact aaaggtaagt caaattcacc tgcaccaaaa
    67801 aatacaccaa ctggtcaaca gaaaaaatct aaaggtttat ttaagaaaac taaaaagtct
    67861 aaccctcatg aatagataaa ataaactatt taaataatta gacaattatt tttagttaat
    67921 ctagtattaa atttgatatt attaacaaga aaaatcaggt agtgctctaa gcactacctg
    67981 attgatttta atagttttat ttttttcttt ctatgacact ttctctatca acaattctat
    68041 aaggtaattc tattttctta ttttcaatta attccttatt tattaacttt atgaccattc
    68101 ttattgctac tgctcccata tcgtataaag gttgatatac tgtagtaagt ttaggtctat
    68161 acattttagc tatcttaaca tcattaaatc ctgaaactga tatatcttct ggaactttat
    68221 atccagcatc acatatagca tttatagcac ctatagcagc ctcatcacct gttacaaaag
    68281 ccgcatgagg tattattcca tcatctaata gttctttcat actattgtat ccactctcat
    68341 aatcagttcc accatactta atcaaactct tgtctaattc tatattgttg tttgaaagtg
    68401 ctttctcata accagcaagt ctttccattt ctaaaacagt atcatcttta ctagtcatta
    68461 taaaagctat cttttcatga cctttcttta taagatgctc tgtcatatca aaagtagctt
    68521 cttcgttact agtacttact gtatatatat cataatttct agcagtttta cttatatatg
    68581 tcgctggtat tccacaattt tgtatatagt tgatatgctc ttgttcaact atccacgaaa
    68641 tcataactat accttccact tgttttgctc tcaatagatt tatactctta agttcttgct
    68701 ctttatcaga gtatgtattc gctaaaagaa tatcatagtc atacatttta gcaacctctt
    68761 ctattccatt taacacctca ttaacaaaag aatctgaaac ttctggaact attaccccta
    68821 ttaattgact tttctttgtt actaaacttc tagcaagcgg atttggtata tatccagtct
    68881 cttttataac ctctaaaact ttttgtttga cttcatcagt tacaggtttt gaatcattta
    68941 taactctaga tacagtagat attgacactc ctgcttgttt agcaacatct tttatcgtta
    69001 tattgccttt catcttcatc ctccttattt tactaaattt atctaaaact gaaccaaatt
    69061 tttgaaggtt cctattttaa ctacatttat ataagttttt attttaccat aaaagcaagt
    69121 acatttaaat acattatatt ttatattata ccctatattc aacaaattta ataatattca
    69181 ttcttaattt aaatcatatt aaaaaataaa ataaaaaaaa tactggtata aaataccagc
    69241 attttttatt ataattattt cagtattagc agccgcagcc cacttcacca tcaaagaatc
    69301 caccacttga acaagttatt agtaataata ttaagaaagg tatccatgac attatgtcaa
    69361 tgtctctcca gcaatcttca aaagctaaga ataggaagaa tagtactatt atccaccatc
    69421 ctcctccacc aaaacatcct tcttctccaa aaaatctatc taacataaca aagccctcct
    69481 ttttttaata actgtactct tattctaagc atccaccaca gcagcaaagt attaataaaa
    69541 ctattaggaa tggtatccat gccattatgt caaattctgc ccagctatct ccaaaagcta
    69601 agaataggaa gaatagtact attatccacc atcctcctcc accaaaacat ccttcttctc
    69661 caaagaatct atctaacatt atacgttacc tcctgttgat attttgttga gcttttcgct
    69721 cctaacatat actatgcatt gggtttccat tttgctaatg tatttttatt tttttttaaa
    69781 attttttaat ctgaattaaa aaaggcaaaa ccataacttg tataagttac tggttttacc
    69841 tatttaataa tcaatatttt ttagcaacaa caaccatcat cgaagttaaa taataacaac
    69901 actattaata taacccatat ccatatattg tcatcacata ataaatcttc taaaatgtct
    69961 gtgcataata ataagaatac tataactatt attatcaaca ttttattacc aaaaaatcct
    70021 tcgcatcctc caaagaaacg ttccatattg tcttctaatt ttgtcataac taatcctcct
    70081 tgaatcatta agagactaag ttttgtctct ttaattaaat atatgtagta atagacagat
    70141 aagttacttc taaaaaattt ttattgatta gtttatttat ttctttttca ccaagtttat
    70201 tgtatctatc aacttcatca agataatctt ttttctcctc tgatatagta tagattaaac
    70261 tttctattga ttttattttg tactccttat atctttctat caagaaggat gtttttgaat
    70321 tttctattcc tttctttaca tgcattaacc ttgatatgta gtcttctttt tcattagata
    70381 cataactctc cttttcagct acatcttcaa ggattaaatt ggtctccatt acataatcct
    70441 ctatacgttg catatctaaa gttattgaat tataataaaa atttactgct ataagtaaaa
    70501 acattcctat tgaagttagt aatagtccta catatttcat agcatttcct cctaagttat
    70561 atttgttatc aataaagttt attcatcaaa taatacttta ttactacatt tataaaattt
    70621 tattattttt tatagattcc atattgaaaa attcttgata ttatattaaa ctaacattaa
    70681 aattaattaa aactgcttta ggaggcttaa aatgtttgaa aaaataaaag aaataatagc
    70741 agaacaatta ggggtagaca atttagatga gataactatg gaagcatctc taatggatga
    70801 cttagaagcc gattcattag atgctgttga aattattatg gcacttgaag atgaatttgg
    70861 aatagagata ccagacgagg aagctgagaa ttttaaatgt attggtgata tatgtaaata
    70921 tatcgaagaa aacaaataat atcgttttgt ctacaaatat aaatagtctg tgtaaacttc
    70981 tacataataa attatattag agttcacaca gactagatta gattgattca caatatacaa
    71041 gagataatct cttatattta atttatacaa atatataaat tacttttctt cataaaacgt
    71101 cacattcttt attattatat ctatagtccc atcttgattt tgttttacag tatacttcat
    71161 tgggtcttca aaatcagtta gattcccttt tatatcaaaa ccattatccg tttttatact
    71221 tcttttttta agctttttct caacccattt tttatctata ctaaaacttt catcaagacc
    71281 tttttcttcc atatgctctt taaagctatc ttttaactca tcatctttaa ttgaattatc
    71341 aacaaagtca tttatatcaa cttcatgttt ttcctttagt gtataattta atatacttct
    71401 tacatcttca gcttgcttta tatcattact aagagcattg gttatccaat tttcagctgt
    71461 atttttaaac accttggtct tgtacttatc atcatctatt tttttagcat ttaaaaattc
    71521 tgtcacaaac ttagattctg acccttcttt ttcagcatcc ttatctaaaa gccttagatg
    71581 aaactcatca tttatgccac ttaaactaat caaagctcct tgcttttgtc ttaaagtctc
    71641 tggtatacca atttcatttg gaaccatttg aatattaaat ttatcatcta caaattcaat
    71701 tgaatgagtg tacaactttt tataatctaa tttaagtata gctacactct tttcatcttt
    71761 aatagtgtat aaacaaattg ccaaatcaca agattctagt gcagcattaa ttttcataac
    71821 atcaaacaaa taagatgcaa tttctttaga atttttcaaa aaagtacttt catcatatat
    71881 tatttgttca caacagtttt taattaaatt atcattataa tctttaaaaa caccttttct
    71941 taaatcctca tcttttgcaa ttctttttat ggctttctgg aaaaaaccat ctacctcttg
    72001 attaactttg ccttcaaagt catttaatat tggaacatca ctatttttgt ccaaaacatg
    72061 tattataaat ttatgtatta tcatatatat caccccatta tcttaatttc gatattaact
    72121 cttttatatc ctctggtata tctgctttaa attttaattt ttcttttgtt cttggttgtt
    72181 caaactctag cctgtatgca tgaagtgcct gcctatttat aagttcttca tctacacaac
    72241 catacaactc atcacctatt attccatgac ctatatgagc catatgtacc cttatttgat
    72301 gtgttctacc agtttctaag cttacttcta ataccgttgc attttctagt ctttctatta
    72361 ctttatagtg agtaacagat gattgtcctc tttcatctat tatcctcttt attgaatctt
    72421 ctgtaggtct ataaattggc tcatctatag ttccctcatt ttcttttata attccatcaa
    72481 ctactgttat atactttttt tcaactttat tttcactcat tgctgtggat aaagtatgat
    72541 gtgcataagc attttttgct acaataacta accctgaagt attcatatct aacctattta
    72601 caaatcttat ttttacattt tctttttgat tatctatata gtaactaata ccatttgcta
    72661 ttgttttatc atagtggctt tttgttggat gaactaccat aaatggaagt ttattcacca
    72721 taattatatc aaaatcatca taaattatct gtaaatttaa atcttgaggt tcaaaatttg
    72781 ctttttcctc atttattttt acttctatta aatcaccact atacactttt aaactcggct
    72841 ttttatatac tccatttact aaaacactct tttccctctt catttttgat aatgacctaa
    72901 ctgagaaatt tagcttgtcc aataaaactt cttttaaagt catttcttct tcatttgtat
    72961 acgatataag attatatctt tgattctctt ttttaaacaa acttttacct actttctttt
    73021 atgtcttcct acttttttta tatctttaaa atcatgatat tatatatttt acaccatttt
    73081 tgtttaatag ataataatta tttttaacta taaaaacctg taagaataac aaatagttat
    73141 tcttacaggt taaattcata gttaaatatt taatttgtaa atattataat ctaaaactat
    73201 ctcttaacta ttaaactagt tcccattcca ccacctatac aaagtgtagc aagaccagtt
    73261 ttagcatctc ttctcttcat ttcatataaa agtgtagtaa gtattcttgc tcctgagcat
    73321 cctattggat gtcctatagc tattgctcca ccattaacat taactttatt catatctata
    73381 tttaagtctc ttattacagc tacagattga gcagcaaatg cctcattagc ttcaactaaa
    73441 tctatatctt caatagtcat attagcagct tctaaagctt ttttagttgc tggaactggt
    73501 ccatatccca ttattttagg gtcaacgcca gctgttccat aagaaactat agttgcaaga
    73561 ggctctattc ctagttcttc agctttttct ttagccatta ctactagcat agcagcacca
    73621 tcatttattc ctgatgcatt accagcagta actgttccat cttttttaaa tgcaggtctt
    73681 aatttagcaa gtttctccat tgtagtacca ggcttaatat attcatcttt atctactaca
    73741 gtgtcacctt ttcttccttt tataacaaca ggaactattt cttcatcaaa ttttccttca
    73801 gcttgagctt tttcagcttt attttgactt gcaagagcta attcatcttg ttcttctcta
    73861 gttatattcc attgctctgc tatattttca gcagtaatac ccatgtgata gttattaaat
    73921 atgtctgata atccatcttt tatcattgaa tcaacaaaag cagcatcacc cattcttgca
    73981 ccatatctcg cacttggtac taaataagga gacatactca tattttcagc tccaccaact
    74041 aacattatat cagcatcacc caatgctata agctgagatg ccattgaaac agatcttaat
    74101 ccagaaccac aaactatatt tatagtcata gctggttttt ctactggtat tcctgctcct
    74161 aatgctattt gtcttgctat attttgtcca agacctgctg taagtactcc ccctaaaaga
    74221 gattcatcta tcatatctgg agttatatta gctcttttta tagcttcttt agctgctgtt
    74281 acccctaact ctaccgctga aactgattta aatgctcctc caaaacttcc tactgctgtt
    74341 ctagctgcac tggcaattac tacttctctc atattcatta cccccattaa attagatttt
    74401 tcatatatcc gaaattgttt ttttaaacaa ttttatttaa atttttaatt cccaaactct
    74461 tatttattat aatcatagaa tcctatctta gtttttcttc ctaattgatt agctctaacc
    74521 attttagcta aaagtggatg aggtctatat ttagtatctc caaactcagt atataaaaca
    74581 ttcattatag ctaaaacaac atctaatccg attaaatcac ctaatgctag tggtcccatt
    74641 ggatggtttg ctcctaattt catagcttca tctatttctt ctttacttgc aacaccatcc
    74701 gcatatatac caacagcttc atttatcata ggtataagta ttctatttac tacaaatcca
    74761 ggagattcag atacatctac tggtacttta ttgatactct tagataattc aaatactgta
    74821 tcaaaagtaa cttttgatgt taactgacca cttataactt caactaattt catcatagga
    74881 actggattga agaaatgcat tcctataact ttatctggtc tcttagtaga agaagctatt
    74941 tctgttatag ataatgatga agtatttgtt gccaagatag tatcttcttt acataattca
    75001 tctagtaact taaaaacatc tttctttata ttcatatctt ctacagatgc ttctattatt
    75061 aaatccatat cttttaaatc ttcatagtta gtagttgaac taacatgact taatatttct
    75121 gcttttgtag cctcatccat ttttccctta gtaactaact tagttaaatt tttatctaat
    75181 aaagctaaac atttatctat agcaccttga gttctactct ttaaacatac atcatgtcca
    75241 caacttgcaa aagtttgtac aataccactt cccatagttc cactacctat tacagctaat
    75301 ttcatagtta taacctcctg ttattttagt atttatattc tgttaactag attaaaatac
    75361 tattcaatct agttaacagc aaatatattt ttaattagat ttttaccctt ttataaagtt
    75421 ggcttctctc ttttcaacga aagctgacat tccttctttt tggtctttag ttgaaaaaca
    75481 aagtccaaat aaattagatt ctatatctat tccagtattt atatcagttt gagcaccaag
    75541 ttgtattgct tctttagagt atctaactgc aagttgagca tttttagcta ttatcttagc
    75601 taatttctca acctcttcta ttaaaatttc tggctcaacg actctattta ctagccctat
    75661 tttttcagct tcatcagctt ttataacttg acctgtaaag attaattctt ttgcttttgc
    75721 cattccaacc aatcttgtaa gtctttgagt ccctccatat cctggagtta ttccaagagt
    75781 tacttctggt tgaccaaatt tagctttagc agatgcaatt cttatatcac atgccattgc
    75841 aagttcgcat cctccaccta aagcaaatcc atttacagca gctatcacta cttttttact
    75901 attttctatc tctccaaaag cttttgctcc taatatacta aaatctttag cagctacagc
    75961 atctaaatct ttcatgtatg caatatctgc tccagctaca aatgcctttc cttcccctgt
    76021 caatattaca acatcaatag tttcatcatt attaatatct acaaatactt cataaagttc
    76081 ttctaaagtc tttgaattta ttgcattaag ggctttaggt ctattcattt taactgtaca
    76141 tatatttcca tttacttcaa cagctacatt ctcataaact ttaacatcac ttgtactcat
    76201 aataccctcc ccaagaaatt agttagctaa aacttcacct ttttcttttg caacacttaa
    76261 ctgactgata agttctggaa gtactttatg aacatctcca actataccaa catcagcata
    76321 tttaaatatt ggagcttctg gatttttatt tatagcaact ataaactcag catcttccat
    76381 accagctata tgttgtattg ctccagatat accacatgct atataaaggt ctggtcttac
    76441 agttttacca gtttgaccaa cttgtcttgc tttatctaac caacctgcat ctatagtggc
    76501 acgagaacca gaaacttctc cacctataat ttcagctaat tcataaagta tgtctaagtt
    76561 ttcttttcca cccattccac gtccagcaga aactaatatc ttagcatctt ctattttaac
    76621 ttgtttctta gcttctttta ttacttctac aacttgaact aatttatcag catcattaaa
    76681 ttctaccttg aaacgattaa ttacagcttc tttagtttcg tcaggttcat ttttcttcat
    76741 aactcctggt ctaactgtag acatttgagg tctgaaatct ttacaaacta ttgttgccat
    76801 tatatttcca ccaaaagcag gtcttgtcat taataataat tttgtatctt cagctactgc
    76861 aagacctgta cagtcagcag taagacctgt atgtattcta gcagaaactc taggtgctaa
    76921 atctctacct attgaagttg caccaaataa tacaactata gggtcagctg cttttattgc
    76981 ttcataagct gcttttgtat atggttcagt tgtatacact gctaaagctt catcatctac
    77041 tactattacc tcatctgcac cataatgtgc taatgtatct attaaacctt ctaccttact
    77101 acctaaaagt aatgcagaaa cttttgtatc atagtctttt gctatttctg tagcctttcc
    77161 tagtaattct aaagaaacag tttgaattac attttctctt tgttctatta ctactaaaac
    77221 gttacccatt ctttatcccc ccttaaatta tatgatatac ttctctttta atttatctat
    77281 gataattcca gctgatgttt tcgcatcttc attgtatatt gtaccagctg gtttaactga
    77341 ttttgtaaat gatttaaata cactagttgg agaaccttta agacctaaat tagaagggtc
    77401 aacctctata tcttttacag tccatgtttc tactacatca ttttcgaaag catcatatat
    77461 tcttccaact ttcatgtatc ttggtgtgtt catatcttta agagttgtta taaggcatgg
    77521 cattttaact tttaagtcat ggcaacaatc ttcaaattgt ctttttacta atacatattc
    77581 accttcagtt tttatttctt cagcatatgt tattgatgga agatttaaat gttcagctat
    77641 ttgaggtcca acttgtgcag tatctccatc tatcgcctgt cttccagcta ttataatatc
    77701 aaaatctata ttttttaatg ctcctgctaa tgctgatgaa gttgcccaag tatcagcacc
    77761 tgcaaatgct ctatctgtta ataatattcc tctatctgca cccattgcta aagcttcttt
    77821 taaagccata tctgcttgag gaggtcccat tgttataaca gttacatgag cacccatttc
    77881 ttcttttaat tttatagctt cttctaaacc tgctttatca tcagggttta ttatacttgg
    77941 tactccatct ctaattaaag tacctgtatt aggatctagt ttaacttctg ttgtatctgg
    78001 aacttgtttt atacaaacga ctatattcat aaatccttcc tccatatcta ttttaatatc
    78061 gacctattgt gtatatttta atatttatct attttaataa ttttcctgaa ataaccattc
    78121 tttgaacttc actagttcct tcatatattt cagttatctt agcatctctc atcattcttt
    78181 ctactggata gtcacgagtg tatccatatc ctccatgaag ttgtacagct tttgtagtaa
    78241 cttccatagc tgtttcagcg gcaaataatt ttgccattgc tgcttctact ccataaggtt
    78301 ttcctaagtc tttatttata gctgcttgat atacaaggtg tctagccgcc tgtaccttaa
    78361 cttccatgtc agctaattgg aattgtgtat tttggaattt tgataatggt ctaccaaatt
    78421 gtactctttc ttttacatat ttaacagttt catcaagagc accttgtgct aaacctaaag
    78481 cttgtgcagc tataccaatt ctaccaccat caagagtaga cattgctatc ttaaatcctt
    78541 gaccttcttt tccaagtaaa ttttctttag gtattctgca atcctcaaat attaactcac
    78601 tagtagctga acctcttata cccattttct tttctttaac tccaaagcta aatccaggag
    78661 ttcctttttc aactataaat gctgatatgc ctttgttccc cttagattta tcagtcattg
    78721 ccattactac atatatgtca ccagctattg catttgttat aaatattttt gagccattaa
    78781 gtatgtattc atccccatct aaaacagcag ttgtttgttg gccagacgca tctgtaccag
    78841 cattaggctc agtaagacca aatgctccta atttttctcc acttgctagt ggtcttaaga
    78901 atttttgttt ttgttcttca ttaccatatt gatatatagg ccatgaacca agagatgtat
    78961 gagctgataa tataactcct gtagtaccac aaactctaga caattcttca actgccatta
    79021 tatatcctac agtgtctcca ccttctccac catattcttt tggatacggt atacccatca
    79081 ttcctgcttt tgccatcttt tccactgttt cataaggaaa tctttcttct tcatcaagtt
    79141 ctgttgctaa aggtttaact tcattttcag cgaagcttac atataactct ttaagcatct
    79201 gatatttttt agaatttaaa tccataatag cctcctcagt attttataaa tattttattt
    79261 tcatttatta attaaaatct cggcaacatc tataataaag tatttgaata tacgtcgaga
    79321 aatttataac cttaatcaaa ctacgctcta tatttatatg tgattatact aaccaattat
    79381 gacattaatt taatcacaaa ttgttaattt aaaatcaact acacctaaaa aaaatctcgc
    79441 tttttggaat tttgtgaaat ttcaagttaa aataagattt ctttcacatt gattacaaat
    79501 aaaataattt gtttacaata tttatatcag ggtatactaa atagtaaata ttgtgtgtat
    79561 agctgttttt tagccatgta cagaatattt ttatcgcata aaaattattt taataaagct
    79621 aaataatcat atttttatct gactattttt tatttttaaa tatcttacat ttataatagt
    79681 atcactcaaa ggataatttt tcaataattt ctaattattt ttttaacaat atttattaca
    79741 ttttttccac ttttttgtca tttttttatt gtttcgaaaa aaaatcagaa ttttttaact
    79801 ttattttgga ttattagttt aaattagatt ttcctcttag atttataaat atttacacaa
    79861 aaaactacct ctgcatagat tgtatacaga gatagttttt tactaatttc tactatagtt
    79921 tactatattt ttttaccaat ttttacaaac atctacccat ttttcacact tagaaaactt
    79981 ctccatttct tcacatgtaa gttctattgc agagttacta ctaccacatg caggaaatac
    80041 tgtatcaaat ctcttcattg aatcatctaa gtacactttt agagaatttt ttaaaccaaa
    80101 tggacaaaca ccaccaatag catgtccagt aaactccaag acttcttctg gtatcaacat
    80161 tttagcctta caattaaatt cagccttata cttcttattg tcaatcttag catcaccagc
    80221 tgtcacaatt aaaattgcat catctcctat tttgaatgag agtgtcttag ctattcttgc
    80281 tggaataacc ccagctgctt cagctgcaag ttctacagta gcactagatt gttcaaattc
    80341 taatatactg tcgtccttgc caaattgttt aaaatactct cttacattac ttattgacat
    80401 taaatctccc tcctagtctg aacttttata aatttcatat tattcttaat tatatctata
    80461 attgatttat ttttcaaatt attccataat attagcattc catgtatcat tattttttcc
    80521 aactactaga tacagtcctt ttgccattgg aatattaaca acatattctc ccttatattc
    80581 tacactcata ccagattcgt taaagtacct ataatcaaaa tttagtcctt ttggaattac
    80641 aaaatcaaca taaccttgat tgtttggttt tattccatac ttcagagttc tttcagttat
    80701 agaatttttt tcattaaata aatctatatt cacatatgaa gaacacttat ttattccctt
    80761 tttattttcc acacaatttt caaacttcat tttagcactg tttaatttat aactatattt
    80821 actattatta cttattttaa atcttacaat agtaccaata tctctgcttc tcctgctatc
    80881 aaaatcaaaa acaatttcct ctaaatgatt tatttcataa tctttgacac ttaccatatc
    80941 tctatatact aatttattta tagctatgaa tagtgtaaaa atcccaaaaa taaaaaatga
    81001 aacttttata aactttttca tttctagtct ccttatattt tgtgctattg tgctataata
    81061 ttaatttaaa ttttaataat taaacttatt cttttttgaa atcctaatag aaaaatacat
    81121 tgatattata aaaattatta ttgttaaaaa tgtcatacta tataaattta tatacttagc
    81181 attagccata tcagttacat aatttgaaag atatactcct ccaactttac tataattaaa
    81241 atgctttact tgatatacaa tcatactaat catcttcaaa agacttccat atacaaaata
    81301 aattaaaata cttactataa gaccacaaac tttcattttt ccatatccaa acttaaaaat
    81361 taaaggaagt aaaatcgtca aaattgctaa aaatatattt acagaaaaaa atacatcatt
    81421 taaaaccata tttctaaaga atactaatga tgtcaattta ctcattaagg acacaattat
    81481 tgttacagaa attattagtc ctacacctaa taaatatttt gagtaaacta tatcttctat
    81541 gctaactggc atactcctta taaaaatcct tgaatcattt tcataatcac actcaaacgt
    81601 atttataaat atcagataac taacgacaat acttactgta taatatgaaa ttgaattaag
    81661 gaaaaaataa aacacaaaaa atagcaatat gtactttaaa ttacggatac catctgaact
    81721 aatccctatt attaaatctt ttcttattaa attgaacatc atctcacctc atttacataa
    81781 taatacatta gttcttctat agtaggattt ttgaccttat gcttatcaat ttctatcaat
    81841 aggcttttta ctttcaagct atctccaact ttaacaagtg cctcattata atatttatac
    81901 tctttaacac caactatact ttctttaatt gcttctagct ctgctttatt tgccctaatt
    81961 attttatatt cttgttctat taattctttc ttaacagtaa aaatctgatt tcctctattt
    82021 ataaaaacaa gataatcagc aattttaatt agattatcag tattatgagt agaaattatt
    82081 acactactac ttccattttt aacaaaatct tgtaaatact gcattatttc actccttaca
    82141 attgggtcta tcccagtagt tggttcatcc aaaatcaata acttagcatt atgactaagt
    82201 gcacttgata acataagctt ctcagattga cctttagata aatttttaat atgcatattt
    82261 tcctctatat caaacttatt aaggtattca tcaaatcttt ctctatcaaa ctccttatag
    82321 aataaagaaa ctatttttct aaattcctta acctttaaat gtggataaaa ttgtaaagaa
    82381 tcatatacaa aaccaatatt gtttttaaaa cttattggag aattttcaat agtttcatta
    82441 caaagttcaa tttctccttc atctgcatca ataatcccca ttataatttt tattaaagtc
    82501 gtttttccag aaccatttgg tcctataatt ccaacaatat ccccttcctt taactctaag
    82561 tttatattat ttaacttgaa ttttcctaat ttttttgtga tattccttat gctaaacaca
    82621 tcttcacctc ttacgcattt tttataccca cctatacata ttttaacaca ttcactacaa
    82681 aggtcattta taaatttata aattaagaat tataaaacta tgttataata caaagtatga
    82741 agaggtgaat atatgaaaag aattataact ataaatacaa accaattaaa taaatccctt
    82801 gagactaaag aactcttaac tagaaaactt atcaatgctg gctttgaagt gtattcagat
    82861 atttatccag atacagagct tattatatca attggtggtg atggctcttt tttaagaaca
    82921 gttagagatt tcgattttcc tgagattccc ataatgggaa taaatacagg gcatctgggt
    82981 ttttttcctg atattttacc agataagatt gatagtttta ttgaagctta tacaaaaaaa
    83041 gattatatta ttcaagaaat gtcacttctt aatgcagaag tatatacaac tactagtggt
    83101 tctaatatgc ttgctgtaaa tgaggttgtt ataagaggag acaagtctag gactatacac
    83161 ctaaatttaa gccttgataa taaacatata caaaatttta gtggagatgg tatgattatt
    83221 tctacttcca caggttcaac agcctacaat tattctgctg gaggtagtat tgttgatata
    83281 aatcttgaac ttatgcagat tacaccttta catccgataa acaccaatgc atataggtgc
    83341 tttacatcaa gcataatatg ttcaaatgaa tctgttataa aaattgcacc agaatataga
    83401 tttgaagatt ctgtattgat tgtcgttgat ggagttgagc atagatttag acaaatcgaa
    83461 aacataaaag ttagtatttc tgatgcaaaa ataaaattac ttagaatgtc aaactatgag
    83521 ttttggcata gagtatctga aaaattttta tagactgtac ttaggaggat ttttaatatg
    83581 aaaataggaa taatgagtga tactcatggt agcttacttt actttgaaaa agcgttaaat
    83641 gtattatctg attgtgatgt tttattacat ggtggagatg tcttatatca tggacctaga
    83701 aatgatattc cagaaggata taatcccaaa aaatttattg agacattaaa caagttagaa
    83761 aacattgtga ttgtaaaagg aaactgtgat gcagatgttg accagatggt tatagaacac
    83821 cctattcaga gtccttatgt catgagccaa tttggtgaaa ttagaattat attgaatcat
    83881 ggttatacag aatcagaaga agaaattatt gacaaagcaa agaaaatggg tggtgacata
    83941 ttagttttag gacatactca tgtaaaaaaa ttatacatgg atgataattt aatagtaata
    84001 aatccaggaa gtacttctat cccaaaagat ggaagccatt ctgtcgcaat tatagatatc
    84061 ataaaaactg atgatgagga tgaacttgaa cttgatataa acttaattga catcaatact
    84121 gggaatataa taaatattaa tgattagtaa attttaaata aaaacaaagt aaactttaat
    84181 ttattaaatt cataataaaa aacaagtaaa ccgttttatt tctatctcaa ttagaagttt
    84241 aaggtattgt acttaaattt ctaattgaga tagaatctgg tttacttgtt ttattgtata
    84301 ctatattgaa atataactta gtttacttgt ttttactata tattatgcta aagtataact
    84361 tagtttactt attttattat atattcattt tgatttacac aatattactg taatgctaat
    84421 gcctctgcat atggtttact attcttacct ccaccaactt gtacaaattt atcagccttt
    84481 acttttttta taaaactttt ctgtgcacta cttaaacttc cacttgcaag tactacaggt
    84541 gactttgttt ttgatgctaa tactccagca gcaagaccat caactaaatc agcttctcta
    84601 ccacttccat cttttgcaaa atacatatta ttaaccttac ttgatttccc ataaaacttt
    84661 tctaaaactt ttgcattagt atcttttcta tctgttcctg ctagtctttc tgcatttact
    84721 aactgtcctt caagtttttt acttatactg tactcaccac ctactatgta tgtctcagtt
    84781 gagttttgtg taataaaatt ctttgcctca cttcttatgc tatctttacc tgtatatatt
    84841 atagctgtat tatcacttgc cgctggactt gatattgaag ttgcgtctgc cagtccatta
    84901 taaccattaa ccactgccac ttttgagaca cctaaatcac cagtatcatc tagctgttta
    84961 gtaagaagta aagatgtttc ttctctatct gctccaccaa ttctactaac taatactccc
    85021 atatcttcaa gaaattcttt tacacttgat gaaatagctc cttcacttcc aattaaaata
    85081 acttctgctg gattaagcct ttttatttcc tctgttacat tatatggtat actattttta
    85141 ttggtaagta gtattggtgc atccaattta cttgccaaag gagttgaagc caatgcatct
    85201 ggcaatgaat ttgagttaac taaaaacacc ctttctgaac cattattcca tccactttga
    85261 gatattttta tggctgtatc aaatctatct tcaccaataa gtgtttcctc ctttggagat
    85321 tttctgcctt gaagataatt attcatatct acctctgtat tttgattttt actaatagtg
    85381 tctgcatata cacaacttgg catcataatc ccaagtgaaa gtacaaacgc tattattttt
    85441 ctagatttaa ttttcaatac aattccccct tttaaatgtt aatacctatt aatatccata
    85501 ctttttattg ataccctaaa ctaaaaataa ttatctttta taaaaataat cataaaaata
    85561 gctatatcat ttcagataca atacaaactt atactaagct tgacttataa agaatgatat
    85621 agctattata actttaaatg cttaattttt aaatactttt taactaaact ctttcagcat
    85681 atttttcagc tattcttaca attaatttag tagctttctc catagaacta actggtatac
    85741 actcattttt cccatggaag tttaatcccc cagtaaatat atttggacaa ggtaatccat
    85801 taaaagataa tcttgctcca tcagtaccac ctcttacagg aactaaacgt ggttttatat
    85861 ttaattcctc catagcttct ttagctatat caactataaa cataactggc tcaatttttt
    85921 ctttcatatt gtaataagaa tcttttaaat ccaattccac tctattatca tatttcttat
    85981 ttatttgttc tatattctct accataatag attttctata ttcaaatttt tctctacaat
    86041 ggtctctaat aatataagac atacttacat tctcaacatt tccatctata gaatttaaat
    86101 gccaaaatcc ttcatatcct tctgttgttt ctggtctttc atctgctgga aacatttctg
    86161 atatttcagt agctatatgt atagcattta ccattttatt tttagctgaa cctggatgaa
    86221 catttctacc atgtatagta atagttgcat ttgcagcatt aaagttttca cattcaagtt
    86281 ctccaactat tcctccatct aaagtatatg catattttgc tccaaatttt tcaacattaa
    86341 ataaatcagc acctctacca atttcttcat ctggtgtaaa tcctattttt atatctccat
    86401 gcttaatttc tggatgattt attagatatt ctattgcagt cactatctca gctataccag
    86461 ctttatcatc agagccaagt agagttgttc catcagtgac tattaaatcg tcacctttaa
    86521 attctaccaa ctcaggagaa tcctttacat acgtaataac atttaactct tcatttaaaa
    86581 ctatatcttt tccatcataa ttttctatta ttcttggttt aatatctttt ccactaacat
    86641 cttcaattgt atctaaatgt gatatgaatc ctatagtatc cacaccatca gtatttcctt
    86701 ttaaagtagc cattatataa ctattttcat ctaaactaac atcatcaaca cccattgttt
    86761 ttagctcttc aactatatac ttagctaaaa ccctttgacc ttctgaagat ggacagttct
    86821 cacactgaga attagatgtt gtatcaaatg atacgtattt taaaaatctt tctactactt
    86881 tttgcttcac gtatataccc tctttcttaa taagattaat gaaatttttt atttactagt
    86941 gaataaaatt ttatctttta aaaaatttat caattattat aattaaaaaa tatccacctt
    87001 cttaagtata tcatgcatac ataccaaacc caaacaaaaa attactccaa ttattccttt
    87061 tacttggatt ccaataaaaa tcgctgctag ggtagctaat ggatttagtc caacatttac
    87121 cgatactagt ttaggttcaa gtatttctct aatcaaagac aagacaaaaa atatcacagt
    87181 catgcttata gctataaaat aattttttat aagaaaataa taaacaatta ctggaagata
    87241 tattgttatt atacctagaa atggaattaa atccatcaaa gcccccacaa atcctactat
    87301 tagaccgtat ttcaatccaa ataaagcaaa acttccccat attgcaaaaa atgttatagc
    87361 catgagtatt gtataggctc ttatatatcc aacaagtgaa agacctgcct ctttctttac
    87421 gttttttacc ttctttctga catcaacagt gaacatattg taaaaactat tttcaatctt
    87481 atcaaggtct tttgctataa agtatgtagc aataaacaaa gtaattataa atattataat
    87541 atatggaata gaagtagcca atccaagtat actagtaaga agattttttg taatttgcat
    87601 tacttcacca ctgaatttgt ttactaattg ttctatatca aagttggcta tttcttgaaa
    87661 tgacttcata aaatcattta ttttatttaa aaaatacata atagtattac ttatatcttc
    87721 aggattagca gatatattat ttaaaaatcc cattagttct ttcactgaat ttattactat
    87781 tattgtagta actgtactga ctatagccac tgcaagaaaa cttagaacaa gcgtagagat
    87841 acctttattt atatgaaact tattttctaa cttttgagat ataggattaa tcataagtgc
    87901 tattatacca cctagaaaaa atggagctat gtatggaaaa gctttgtaaa taaaaataaa
    87961 taacaatgta tatatacaaa aaaagatagt gttgttcttt aatttatata aaaaattatt
    88021 ttctagtatg ctcattttca aaatctcctt tcttctaatt tatattttta ttttgtccat
    88081 ttcatactag ttttatttga atataaataa aaagaagtat atgaatataa aagccaattt
    88141 ttatattcat acacttctaa taaatttaag aacattatta cattatgtat atattcttat
    88201 ttttttaatt ctattttttt ctatactttc tatacaaaat cttatattat cgacttcaat
    88261 tacttcattt tcttctggca atctgcttag gtgtccaatt ataaaacctc ctatggaatc
    88321 aaactcctca gattctagat ttacaccaat aagttcatta acatcaccaa ttttagtact
    88381 tccatctacg atatactcat cttcttttat aacttgtatt tcatcctctt cttcatcata
    88441 ttcatcctct atatctccaa caattacttc tactaaatct tctatagtta aaagtccaga
    88501 tgtaccacca tactcatcta caactatagc catctggctt ttttcaagtt tcatttcttc
    88561 aagaagttgt gttatctttt tgaactcata cgtgaaaaaa ggctctctca tataattttt
    88621 aatatcaaat gactctattt cttcatcaga taaaaatata atatctttta tgttaagtat
    88681 tcctacaata tcatctatag tttcttcata cacaggcatt ctacttaatt tttcagtttt
    88741 aaacacctgt attatctcat cataactatc ttccatatct atagctacca tatctattct
    88801 ttgtaccatt gcatttttgg cttgcatatc tccaaattca aacacattat ttatgatttc
    88861 tctctcttcc atttcaagga cgccttcttc atgacttaca tttaccattg tttttagttc
    88921 ttcttcagtt atgaacgatt tagctccttt atttgttata ccaaataatt taaatataat
    88981 atttgtaatt atattaaata tccacactat tggtcttaat ataaatataa ttgcttttat
    89041 aggtttggat actaatagag aaaccttttc tgaattattt gctgctattg tttttggagt
    89101 aatctcacca aatattaata ctaatactgt cataacagct gtagcaagtg ccactccttt
    89161 ttctcccatt aatcctataa acaaagatgt tgatatagat gttgctgcta tatttacgac
    89221 gttatttcca accaaaatag aacttaaaag cttatttgga ttttctatta atgaacttac
    89281 tagcttagct cctttaactc cttcatcttg catatatctg attctgattt tactcaatga
    89341 cattaaagcc gtttcagatg ctgagaaaaa tgcagatcct ataagtaata ctattaaaaa
    89401 tataatctga atcaaattat cgggcgattc caacacttac cacactccta attacacgtt
    89461 tttatattaa tattaattat aaataacttt aatattagtt tttattatat cacaattaca
    89521 tattatttgg aaatattaga taatatattc aattaacata tattttctaa ctatattcaa
    89581 tttttacttt tgaacctatt ccagcctcac tagatgaaac taatagctta acaggaactc
    89641 tatttttaag ttcctcgaca tgacttatta tacccacact tagattatta ctatgcaatc
    89701 tttccaagga ttctataaca atttccaaaa gttcactatc taatgaacca aagccttcat
    89761 ctaaaaagaa aaattctagt ggtgcacttc cctttaattg tatttgagat gaaagagcaa
    89821 gtgctaatga taaagatgtt aaaaatgtct ctccaccaga tagagtatca atacttcttc
    89881 tttctcctcc attaaagtta tctctcatta caaagtttag tgttgaatca atttcaagtg
    89941 catatcttcc ttttgttatt ccatccaatc tttttgatgc ttccaacgct atatatttta
    90001 attggtttgt agaaacatat tctacaaatt tatttccttg tacacattta tctaattctt
    90061 ccaataagtc cacattgtgt tcaactactt taagttgttt attaaaatca tttatcttat
    90121 ctaaagagtc ttttaatgtt attaactgat tttgattggc tccaatattt ttggatatat
    90181 ttcctatttc tactttcaaa ttataaattt catcttttaa ctgttcaaag gactccttct
    90241 ttacacttct tccatttaat ttttcttttg atgattttat tttaaatgct aataattttt
    90301 gttcttcttc atgttccagt atttcttcaa tcaatttttt tacttcatca gcatctaata
    90361 aagctctttt tactgcatat atgctttcaa atttattttc tgccaacagt ttatttagtg
    90421 ttgatttttg gtctttatat tgttccttag cagttttaag tctaccatct atattgtgct
    90481 tttcagcaat gtttttttca tattctaatc tctgctgttc caattttttc ttgcttgatt
    90541 cctcttgctc taatatctta catatatctt cttcaacact atgtaaaaga tttttagcta
    90601 aatcaccttt tgttatgtta ataacttctt tatacttatt atctctactc aatttttttt
    90661 ctaagtataa ttctctagcc tttattaact ctatctctat ttcatgtagc ttactttcat
    90721 tttctcttat tttaatatct agagagtctc tattttttaa taaatttgaa tgaccaatac
    90781 ttagtaattc taattccttt tcattctctc ttatttcttt tacttttgac aatagattgg
    90841 agactttagt aatcgtcttt aatcctatat actcttgttt aagtttttta catttatttt
    90901 ctaaaccttc tatttctatg tttaaatctc ttgttaattt cttataatta ttcaagctct
    90961 ctcttatttt taattcttct ttttcaattt tatttttttc ttctttggct aatgttactt
    91021 tattttcggt actctctttt tctttctccc actcctgaat attagacttc aataatgcaa
    91081 gctttctttg ctcctcatca agttttttta ataattgact agatggaata tcccccagtt
    91141 ttccttttac atcttcaagt tctttagtct tcattttttc tatagataaa tacccactta
    91201 atttagcatt taattcctct atattgtttc ttatacttat tttttctttt tctaatttct
    91261 ccagcttttc tttgacaaag gatatatttt catcatactt agttatatta tgattttcat
    91321 gatgttttga cccacaaact ggacaaggca tattttcttt taattcacgt ctaagttcag
    91381 aggccaaatt taaatacttt agttgttcta attctttttc taggtcatct ctattctttc
    91441 tattattttc aagtttttca tttagtaaat ttacttccct ttcagtatta aacttacttt
    91501 caagtattat ctttaattca tcttgtatac tacttttttt gatttcattt tctttagtat
    91561 tatctgcctt atttcttaac tcagtaacat attcagattt taaaagtaaa tctgcactct
    91621 ttccaggaca ttttttaaga agaacatcca agtgaagaga taaattttct aaattacgat
    91681 ttacatcatt cttatcttta tcaatatatc taacttttaa gtttatatct tctgtctctt
    91741 tgagtatttc ttctagttta tttatctttt gatttttttc ttccaataca ttattgtaat
    91801 ctttctcgta ttcatatgct agaaatattt tttgttttaa ttctgcactt atatttactt
    91861 tattaatctt tccttcaact tcttttatag atttagtaac tgcatctttt ctggactctg
    91921 acatctgctt tactttttct aattcaactt tagttttatt taagttaatc ccactttctt
    91981 ttagctcttt taactcttta tctaataaaa ctaattcttc ttctaatttt attgcctgtt
    92041 gtaatcttat tttttcttca cttaatttag gaacttcttc attcttaatt ttgtttattt
    92101 tttcatatct attttttata acttcaagtt cctgatttaa tattactaat ttcttttcta
    92161 aattacttac tgtaaagcta tcttcatcta tctttttttc taaattttga actgaaccta
    92221 tgtatgggtc taccttttta gcattactat cattttctac aagagcaatc ttttctttta
    92281 tctcaccatt tttcaaatca agctcatttt ttctaagttc atttttttct agctttaatt
    92341 gttcttcata tactgtttta ctttcttcgt aagaattttg agctaggtct aaagcattat
    92401 tcttatcttt ttccaaattt tttaactcta ttaattcttg atttatattg ttgtatactt
    92461 cttctgtaat tccatcatat tgacttaatt ttgattttaa atctttcaaa ctttgtaact
    92521 gtaaattttt tctctttttc actttttctc caagacttct tccatatttc tcaagattaa
    92581 aaattctctc taacatatct cttctatctg cacgtgataa tcttagaaat tcattaaatt
    92641 tgtcttgtgg taaaactact gacctagtaa aatcatttgc agttagtcct acaacttgag
    92701 ctactttttc atttacttcc acaactttat cagccaaaac attttgggta ttgtcattta
    92761 atacttctat taatctggca ttagaggttt ttgtccctgt tttacttcta gcaatggttc
    92821 tatctacaat gtatcttctt ctagtgtttt tacttcctat ctcaaactca tacgatataa
    92881 ttgccttatc gcacacactg tttatatatt cttttgtatt tctggatata tttccataca
    92941 tagcaatagt tattgcatct aagattgtag attttccact tccagtagtt ccaaatatcc
    93001 caaacaaacc tctttcaatt aatttttcaa agtctataac ttgtttatca atatagctat
    93061 tgagccctgt aagttctaat ctaattggtc tcatctgctg attcaccttc ttcacttatt
    93121 atatctagaa ataaatccat aagttctcct tttggctcta cacctttact aaaagaataa
    93181 aattctctaa ataactctgc catagacttt tcttttatat ctacactttc ttgttcataa
    93241 caagatgtta ttattggctt tatttctatt atgtctttta atagttcttt cattttttta
    93301 atttcattct gtgatattac ctcttcagta tttatttcaa agtatgacca aatctcttta
    93361 tcttgatttt gttcacatat atctagtgct tcttctattc cattacattt aaatacttct
    93421 ataggtttat aattattaaa atatacatct tcaattattg gtttttcacc agcttttata
    93481 tccactatgt atgccccttt ggtatatgct ctttcatcct tgctatattg aagtggagag
    93541 ccagaatagt atgcatttaa acgttcagaa gctttttgtt gtttgtgtaa atgacctaat
    93601 gcagtatatt gagccttttc tggcaagtct tttctttcaa ccaaaaaact tccacctagt
    93661 tgtataggtc tttctgattc agtactctct ccacctatta caaatatatg tgatacagct
    93721 atatttatag tatcacttct aaaattttct tctaaacttc taaatatatc tcctaccttt
    93781 tcagaataat ttttttgttt ctcaaaatca tcttcacttg aaaaaacttc atttaatctt
    93841 ttttcacttg gataaggtaa tgtagcaacc acaacatttt ctccatttat attcagtttt
    93901 gtacatccct gagttgcaca tgttatttca aaccctttat acttagcttc tatcgtagca
    93961 cttaatggat aaccatatat aagtatgcct tgttcatgtg ctagaggcgt tattgcagaa
    94021 agtctctctg gattatcatg atttcctgaa attattaata cacacctctg accattatta
    94081 gcaagtcttg atacagtctg ataaaatagt ttttctgctt gtgctggagg attagaagta
    94141 tcatatacat ctccagcaat tataaccata tctatttcat ttgattctac tatttttata
    94201 aattcctcac aaaactttgc ttgttcctca attctagaat ggccttctag ggatttccct
    94261 agatgccaat ctgatgtatg aataaatctc attgtttccc cttcctctat cttttaggtt
    94321 taatttatat ataaactaat aacaaacagc ttcatcaact ccaaataaat atatacattt
    94381 ttcttttacc gacttaccag ttaaagtttc aatgatatct gcatacaaat ccaactgttt
    94441 tttatatttc tctattattt gatttatatt ttcttcattt acaaaatctg ttttataatc
    94501 caccaaaact atttgattat cttcttcaaa ataagcatca actatccctc ttaacatgac
    94561 actttcttca tcataaagtt ttttatcatc attgtttata agcttttcgt aaatatatat
    94621 gtctttcata tttacttgtg cgtaaattga tttttctcta tttataagtt cagcattcaa
    94681 cattcttttt cctatgttag attcaaaaaa cttatatatt ttatatggat ttactatact
    94741 agcctgtttt tctgttatta taccttttga aacaaaacct cttatttgtg attttatatc
    94801 atttacatta cttacatttt ttaagtctaa aacctccata actaaatgaa ctattgtacc
    94861 tctttctgct ccacttattt tatctctttc ttcttcattt tgaataaata gaggcttttt
    94921 taatattact ttttgttcaa atatagtatt tattaactct tcttcataat tattttgtat
    94981 cttttttatt tctgtaacag atatagtagc aggttttctt gtgctaaatt catatggata
    95041 tatatagttt aatttctctt ctatttcatt gtaataatca ctgtcaggac tatctacatc
    95101 tattttttca agaatttttt caatactttc tttctcttca ttattcttct tttccactaa
    95161 aatatcattc ttatcccaca actttccata ccattttgaa ttatgttcaa cactaaaaac
    95221 tgcgtctaat cctacttcat ctaataaatt agataaatcc ctatgtttta atacacaagg
    95281 cattatccaa tctaaaaaat ttttaccttt taatatctca tattgtgata ttgtatctga
    95341 attttcaacc ccatttgacc atctctttat actatcttgt atatttctag tagaacctgt
    95401 tataatcaat ttttctttag cccttgtaaa tgcaacatat aaaactctca tctcttccga
    95461 taaattttct atatttattt tgctttttaa cgcttcttta gctatacttg gaaaagaaat
    95521 ccgtctctca taatctacaa actgaggtcc ataccctaaa ttgtgatgat ataaaatact
    95581 ctttttaaaa tcttgagtat taaaattttt acccattgca gagcatataa ctactggaaa
    95641 ttctagacct ttacttttat gaatactcat tattctaaca acatttgcat tctcaccaag
    95701 tgtttttgca cttcccatat cagaactaga cttttttaat ttctctataa aatttacaaa
    95761 gttgaatatt cctttaagac tagtctcttc aaattgtttt gctctctcaa acaatacttt
    95821 taaatttgct tgtctttgac ttccacctgg taatgctcca acataagcat agtatccagt
    95881 ccttgtgtac aaataccata taaattcatc tgtactcatg tacattgact tttctttaaa
    95941 ttcctttaac ttaattaaaa aatctttact tttgtttatg cactcttcac ttggtataaa
    96001 ttcagactca ttttcattct gagaatcttt aaactcattg tactctgctg tactttttaa
    96061 aacctcataa aaaattttat ctttactctg aactctaata tctatcaaat cctctggggt
    96121 aaatccaaat ataggtgatt ttaatacaga tataagaggt atatcttgca ttggattatc
    96181 tattatttga agtaatgaca atattgtttt tatttcaatc gtatcaaaat accccactcc
    96241 gacatcagca tatgttggta tatccatatt catcaactca tctgcaaaca ctggagccca
    96301 tgcagatgta gctcttaaaa gaataactat atctctaaat tccacaggtc tatatccacc
    96361 tattccttta tcatagacct tttgaagttt tccctcttca ttaactttca ttaaatcttt
    96421 gataatcttt ccaaccattc tagcttcaag ttggatatta tctaattttt cttcttcctc
    96481 tatttcactt tctttgttat tagtcctatc gtctttatcg tttataatat catcatcaag
    96541 tttattatct ttttgtatta gatgtatctc tgttgctcca ccaataatag atttctcgtc
    96601 tgtatccatc tcaaaatttg cacctaaatt tagtctttct ttttctgtat attcaatctc
    96661 tcctatattc tcattcatta tattttcaaa tatataattt acagcatcta caacttcttc
    96721 tctacttcta aagtttttat aaagcattat ttttctatgg gaacttccct ttttatcatt
    96781 atagttatta tatttttgca aaaataattc tggctttgct tgtctaaatc tatatatact
    96841 ctgttttaca tcaccaacca taaatctatt tggagtttct gtattggcca cagctttaag
    96901 caggacttcc tgcactaaat tactatcctg atattcatct ataaatattt cataaaactc
    96961 attcctatat ccaactgcta tatcagaagg tacaatattc cctttttcat ctacatcagt
    97021 aagtatattt aaggcaaaat gctctatatc attaaaatct attattcctt tttctctttt
    97081 cttattacta tattcctctt caaatctcag tacaatatta gatattggtt taactatgtt
    97141 ataaagatat tttatttctt ctctaataga atcattatct ttattgaatg tagcacttac
    97201 tatactttct aaagacttct tagtcttatc tcttatggtt tttgcctttt cttttgattc
    97261 ttttatatac gagggagcat cttttgaaat tctttttact ccttttacat aattttcaaa
    97321 ggacatactt gacatctttt tatatgtctc atcccaagac ttattacatg cttgtgaaat
    97381 gtcgactatt tttttatatt cagcagataa cttttctgca aaagtttcta attcttctat
    97441 tgattccact tcttttaatg ccctttccat gtttagacaa agaccattaa tctctatttt
    97501 tacagtgtct aatatagctc tagcccaaat agactgtgaa aaatcaaaat tttcatcaat
    97561 attaaatctt tctgctgagt caatcaacca ttttttaggt tcaggagaag ccattgcaaa
    97621 tgaatatatt cccaaaataa tatcttgtac ttctttatct cctcctcttt ctgcataact
    97681 ttcaactaaa tttaaaaaac cctcatctct ttcttcatat aaatcttcaa atacttcctc
    97741 tattgcttct tgtttcaaaa tagcacattc agtttggtct cctattctga aattagggtc
    97801 taagcttatt ctatgaaagt ttgattttat aacatccaaa cagaatgagt gtattgttgt
    97861 aatactagat ttatttaata aaacaagttg attttgtaaa tgtttatttt ctgggttttc
    97921 atctaaggct tttcctatgg catctcctat cctctctctc atttctgatg cagcagcatt
    97981 agtaaatgta acaactaata acttatctat atcaattgga ttttctctac ttgttatcat
    98041 ttgaattata cgctcaacta gcacagctgt ttttcctgaa ccagcagcag ctgcaaccaa
    98101 tagattacat tctctacttt ctatgacctc tagttgctct tttgtccatt taggagaact
    98161 cactaattaa catctccttt catcattttt attatttctt cattgctctt attatttaaa
    98221 tttttatatt tattatcttt catagttgaa tcaaattgac atatagcaga ataatcacaa
    98281 aagtcacatg atgttccatc tttatgttta tatggagcta tacatatttc tccacttaac
    98341 atgtcttcac acaaatcctt tatagcatgc tttacatatt ttctgagtag tttaaaatcc
    98401 tcatagctta ttgctgaagt acttttgcct acatttccat ctttagtaag acctactggt
    98461 attactaaag agttttttct ttctccatct attaatgatt tatccatctt tttaactatg
    98521 tgagagtctt ttactacaag ccccttcatt ctaagttctt ttaatattgc ttcttgtatt
    98581 tctacatcat ctttatcttc attaaatttt gctattgggt tatttatcct acaatatagt
    98641 attgcagctg gatttatatt tatatcttta tcctttgcac tttcaaggat tgcatctaaa
    98701 tacacaagta attgtaattg tagaccataa tatatttctg ttagacttat ggacttattg
    98761 cctgacttat aatctactat tcttatatat ttattttctc cttcttcaaa ttcatcaact
    98821 ctatctattt gtccaatcaa acttacttct tgtccatttt ctaacactat ttttataggg
    98881 ggatattttc cattgtcacc aaatttaact tcataatcta ttggttcaaa tgaaccttgt
    98941 tttatttgct gactaattat agttatagca gttgtcaaca tattctttaa tctatatgca
    99001 aggtatttat acctctcaga actatttaat atatatcctg gtatctttaa aattatttca
    99061 tcaactatta tacctatctt taattctata tatttttcat caatacctct ccaagataaa
    99121 ttatcttgta aaagttcttt tgaaaaccta tctaaaatat tatgaataaa agttcctaaa
    99181 tctggtggtg taaatgaata ctctttacgc tttcttgctt ttagaccata ttgtataaaa
    99241 taagcaaatg gacattcagc atatttttca agcctagata tactaagaga attactttta
    99301 tacaatgacc ttattttttt ctcttcaatc ctatgaactt gattagtata actaagacct
    99361 tttataactt tttttgttat agaactatag atttcatctt ttaaatagta cctatatata
    99421 tctaaccaaa tactattaat ctcttcttta ttgtaaccat cactgtcata attttttatt
    99481 acatttataa gttcattaaa tgtaggagat ttaaccgtta tttttttaag tatatcttca
    99541 tcagtgcttt tattttcttc tactaaataa cttttatttt ctatatttgg aaatatcttc
    99601 ttaagtcttg atataattat tgatggtcta agtgttttac cctcatggtc cgatattgga
    99661 tatgttatgg ttaaattctt agatgtcgaa gtaagggctt tatatacaag aaactgttct
    99721 tcaaaacttc ttgtctgact atcaatatcg acttcgattc ctttgtttcc aagactttct
    99781 ctatcattat cacttaatat tccactatcc tttgtaatca gaggaaatac tccatcagta
    99841 gttccaacta gatataaata tttggtatct ggatttttca ttctatcaac actacttaca
    99901 agtacttggt ctatactagg aggaactaac cctaattcat attcatcaaa acctaaggtt
    99961 attaatttta taaatttttc taaagaaatt atttcatcac ccataagttc caccatttgg
   100021 tctaatatat ccaccactat gtcccaaact tgtgaatatt gatttgcaac atcaagttct
   100081 cctttatcct taaaatttac tattaaactt tctatagttt ctggcatatt tatatctaat
   100141 aaaaattcat atatatacct acaaatttct tttactctat tttttccttt taatttttct
   100201 tgtaaagtaa ctattggctc tagtactcta ttttttattt catttatttt atcttttaat
   100261 tccagttcaa attcactttc ttcacctgaa agactttgtg ttattctata atcccatttt
   100321 tcatcaaacc atttcttacc tttaatccca ttagccaaga cataattttc taatacgttt
   100381 atatcatcat tatcaattcc tataagtcca ctttttaaat acctaaacat agtttcatac
   100441 ccatatcgtc tattcttcat ttctaaagct gaaataatta aaataactat tggattactt
   100501 tttgcctctc tcttcttatc tataaagttt ggtatattat attcattaaa tatagagtgt
   100561 actaaaaaat catatctatt taaatctctt gtagcaatag ttatatccct atacctgaca
   100621 ttcttctctc taactaaatg tacaatttct ctggctattt cttccacttc tgaatataaa
   100681 ttgttaaact cttttatctt tatattttca gtttgctttg aatatatttt atatggataa
   100741 gcattataaa atctttctag gtgctgtaat tccttaacct tttcaaatct ttttataaca
   100801 cctgtattta aatttacttg tggcagtatt tttattcctt cttcgttgca caattgagtc
   100861 aattttgaat aagtaaattt cgttctagaa aacatatcag ctttactgta cccagtatag
   100921 ttgacatcat ctacagtcaa agagatatta acacttttag atttatttaa tatactcttt
   100981 atgacattgt actgatttgg tgtaaaacct gtaaattcat ctatataaac gcaagctcca
   101041 tctaaataac tgcttaattc aattttactc gccaatgaag ttaacatatc ttgagcatcc
   101101 acataatttt catgcaattt cccttcaaaa gagttatata ttttacttat atcttttaat
   101161 tttaaactta aagtttcatt atccaattct ccagatatat tttctaacat ttcagggctt
   101221 atattgtatt gtttcatttc tgatatcatc tctgtaattg agcttacaaa accagcctga
   101281 gattttgatt ttgaaaacac atttaattct tcacttacat cttcaatagc cctatacacc
   101341 atcattgctt ttccactaga atttatattt acatctgtta atcctcctac ttgtgaaaaa
   101401 actatattac ttagtgtctt aaagctaagc atcctaactc ttaaatactt atctttttct
   101461 tttcctaaaa atagtttact tactctattt tcagcctcaa atgtgtactg ttctggaact
   101521 aaaagtataa ttgatgtcgt ttcatttttt tgagcttctt ttttaatctc atctagtata
   101581 taggtggatt ttccacttcc acttctacct aatacaaacc taagtcccat aaatttccgc
   101641 ctccaaaata ctataatcta tttctttgcc attacataac ttattaaatt cacaatactt
   101701 gcaatgcttt ttatttctat agcacatacg ttcttcttta ttatatacct tttctatatc
   101761 attgtataga ttgtcttcgt atgtatgttc ttcataatta gtgtttttta tcatacttat
   101821 ataattttga attttatttc tatttgtttc atgtttttct tcattatata aaatggtaat
   101881 tggtaagtca tcaaattcag gctgataata tctcatattt atatctttaa catttatgtc
   101941 catttttaaa actttaggta ttacttcttt tgctaaaaac atataaacaa tagtttgtat
   102001 tctattttct acgtgtttat agtcaatctt tttagactcg gttttccaat cccatatatc
   102061 tatattgtta tttccaatta caactaaatc atactttgcc tgtattgtat ctccatttaa
   102121 ggacatcctt acttcatatt ctggcaaata cgtttttcct ttttcaatag gaacaacttt
   102181 ttttatgttt tccatccact ttaaaaactt tttactattt ttattgtcct cattaaaata
   102241 gattccaaga ggtatattgc taaaatatct ttcacaaatc aaatgaaaat ctcttcctgt
   102301 ttttaaagtt tcataatact ctctactacc aacatcatca tttttccaat ttattctatc
   102361 aatatattta tatttaaatt tcagtggaca tgatttatat gtgttaattg aattttgact
   102421 ataagaaaaa tattttaatt tatcgttcac tcatatcact tctctcttaa ctttattttt
   102481 taatagttac ttactgtaca tattgttcta tcccatttta aaagtatttc aagcaatagt
   102541 ttaataactt attatacatt aatttgacct ttttttaata atatgtcgat taagtctgcc
   102601 taaatatata catggttttt gctcttttct cttattacct atatcacttt catctctata
   102661 agcacttcct gaaagtacta acatctcctt tgctctagta attcctacat ataaaagtct
   102721 aatcttttca tttatagaat caatcttcgt tttatgagca taatctgttg aaatacttcc
   102781 tttcaatata gcttcgactt ctgatttaat aattgccata ggatttttat atttttcttt
   102841 taaataccat ttatcactct ggaacttttg attaatattg tcagggaaat tatattcaac
   102901 aagacctagt aaaaatacac aatcccactc catccccttc gacttatggt agttacatat
   102961 tgttatacta ccaggctctg gctcatatcc atttatctca tataccacat ctattatatg
   103021 attaaatacc ttattcttta catcaaacaa taagttatat acatcttcta aatccatatt
   103081 tatattttct gatgctagat attttatata aaaggatata taatcaagta cagctttatc
   103141 ttctttttct aaattaagtt ttttcccaat aaacaaaact aagaggtcta accttattat
   103201 tggatattct aatatctgct ttataatatt tattcctctt ttaaaattta aatatatatc
   103261 actttcttca ttaaattcta ttaaatcatt atctaactta ctaaattcaa aatcataaat
   103321 aatttcttcg gtagaatagt tttttaattt ttctaaaaaa tactttaatt cttcttcatt
   103381 atcagtatct ataaaaactt tatcaagtac aactattaac ttttctatat catcacaatg
   103441 taaaataaag tcaataatag atgctatgtt atttataact ctccttttac tcaaagaatt
   103501 tggccctaat tcttcaaaga ctagattgtt ctctctaagt tctttagcaa cttgtgtcac
   103561 ttgctcatta aatggaacca agatacctat acttttatct ggatatttat tttttatacc
   103621 cttaacgtat ctagcagttt gttctatttc aaatttccaa ctatcatacc actttatatt
   103681 tatattataa tgttctggat taggattttc tttatatccc attccatttg gcacagtttt
   103741 tatttgcata tcttcaagag catgtctaca ctcttcctgt ctaaattcct ttgtaacata
   103801 ttccacaaga gtgtttgcta aatcaagtat atcttttgaa cttcgatttg acatatccat
   103861 cctataacag aaatctgcac tatttataaa ttctttaaaa aacttagggt ctgatgatga
   103921 aaatgttcct gttatactct gatttatatc tccaacccta actaagtttc tattttcact
   103981 agatataatt tttattatat taccttgaat ttcatttgag tcctgacatt cgtcttcaaa
   104041 tatatatttg tatctagttt gaaatttctt tctaagccct tcgtctaagc ttaaagtttt
   104101 ttctgctaaa attaatatat catcatagtc tagtaatcca ttttgcttca atttcctatc
   104161 atataattta tatattggta aaataatttt aagcattcct ttttgtcctc ttgacaatat
   104221 ttcttcaagt ttatctggag aaattccctt atacttaagt tcacttattg catttcccgc
   104281 aaattcaaaa aaacctcttt cccaagcttc aagagttatt tctttccaac gttcatcttt
   104341 ttgctccttt aaaaaccatc taaaagctct ttctccacct tcaaatctaa atctacttat
   104401 acattcattt aatataatat ttttttgcaa atcgtcagct atattaaaat cctcacttaa
   104461 cattacaact tctggctttt cctttattat ttttacagcc aaactgtgta tagtcattac
   104521 ttcatacgaa ttagtatcat ctattttatg ctcttcaaga atctttctta ttctaccttt
   104581 aaaattattt acagcactat tcatatacgt aagaactaat attttaccac ccttgtgctt
   104641 ctgttcaagt aatagtttag ccactaaatt tgttattata aatgtttttc cagcacctgg
   104701 tactgctggt actgccatag taccattatc gtaatttatt attggtattt ggtcttctct
   104761 ataatttata ttaatcataa ttttcatctc ctttatgtga gatttttaaa agtatactat
   104821 ataatatact ctcttggata taaccattaa tcgcatattc acttttatat gcatagattt
   104881 tctttgcatt taatagcaaa ttatagactg tattgtatag ataatatttc ttatagtatt
   104941 cttccatttc atttgtataa attttttttt cttcaaaaga ttttctaagt acaattaaat
   105001 tacttatatc tttttctatt ttcatattcc aagcattact tcctatatct acccatattt
   105061 gtatacttct atctatattt gatgctatat atgaataagg agtagttatt actattttgt
   105121 ctttggattt caattcttct atatcgacaa cagagtaata atcgtttatt gcagtcttta
   105181 aagcttctat aaatatctct tcttttttca ttccaagtaa acttaaactt tcactaaaag
   105241 actcactttc ggctattatc tttttacata acccaacatt ttttttacca tcttttaaac
   105301 ttagcatttt atctatataa aactgaatta aaaattcatg tatttttaaa tcactcttct
   105361 ttttttcttc aatatactgt aaaatatcac gatactgact atgttcatcc atattatcaa
   105421 tacttaaatg tcttgtttca ttaaaaatct taaatgcttt tatcctattt atttctaaaa
   105481 gtgtttctaa aaagcttaag tattcatcat cctttataaa atctaaatat ccatagaaca
   105541 tgcatgtagc cactaccaat gcatttccat atggataatc tacagctttt ttatctttct
   105601 taatattaaa aacatctata tttttttcta tcaaagaatc tctaatttga tactccaata
   105661 tactattgtt tataggagat ataattgcta tatctcttag agatacacct tcttctataa
   105721 gagatatgat tttttcactt attaagtcta acatttcatt gtataattga cttgattgat
   105781 ttaattttat agttgcaggt aataagtata aatcttctat tcctatctcc ttccttttaa
   105841 tattttcttc tttggactta atttttgata ttatcttctc atttatatag tccatatcca
   105901 cattattaaa tacagaataa tccctactat agtcaaaata tatataactt tgtaatgtat
   105961 tatctaatgc ttctgttata aaatcaactt ctgcattact tgagctttca aggctatcta
   106021 ctattatata tctaacttct ttaaataagc tttttacata aaaatcatca ttaagtagat
   106081 actgattgta taaatataca cttaatgaat tatctaaaat ggaatttgat agtaatgaat
   106141 ttatataata tgatataatt tcatccatct gagtgtatga aaatctatat atactatctt
   106201 tatttttctt tgatgaatat attttttctc caataaaatc aaaatcaatt aaattaaatg
   106261 ctgacttatt tatattagtc attatactct ttgctattga tttatttgtt ccagtaatgt
   106321 cttcaaaata tccttcttgt atcctttttt ccttaacttt ttgcactatt aaatattcac
   106381 ttaaactatt tgatataaag gttggagata cagccttttt atttatttca tcacaatttt
   106441 ctattattag tggccaatat ttcaataatt ctttcttcac aaaacttata tatgttgtta
   106501 ttttcagttc ttcactataa tttaatctta aagacctttc atattgtatc tttgtgttgt
   106561 tgtttggtac taataaaaga atacttcttg aattattctt agttttatct aatatttctc
   106621 tatatttatc taaaggttca tttccacatt cttttaaact acttttgtca attaaatatt
   106681 ccacataatc accttcctca attaaattaa gtgtatttta tctaattata tcatattgtg
   106741 taatttacaa aatacaatca aattattgca tttaattaca aaaaaagact atatatacat
   106801 tcttgcattc atatatgcaa atgtacatac agtctctact attgatacac ttatatttca
   106861 ttttataact ttagtataaa tttacattaa gtttttaaat aatttttatt tctatttatt
   106921 ttaatgaatc ttctattcct ttgcctattt gtatacccat ttcttttact ttcgcaggtg
   106981 agtttattaa actcacatct ttctcattat ccaaaaatgc acattctaca agtacagctg
   107041 gtatattatt agttcttaaa acgtataaat aatcttttgt agagtcacta ggaagtactc
   107101 ttgtttttat gcctctgttt gtaagtttaa atttctctaa aattctattt aatatgtttg
   107161 tagctacagt cttagtagtt cctccatttt tatctttaaa cttataaaag acttctactc
   107221 catgaccttt tctattatta tcaccattgt aatgtatact tgtaaataag tctggtttaa
   107281 gtgaattaga taaagcagtt ctacttccaa gagataaggt tttatctgta tctctagtca
   107341 taattacatt tatatccttt gaacgtaaat attcagtagt tgcaagtgaa gtatttaaat
   107401 tgtaatcttt ttcaatcatt cctccaaatg aatttccagg tgctgaacca ccatgccctg
   107461 ggtcaatcat tactgtctta gcaccattat tacttcctgg gtctgctgga gttgtattat
   107521 gtttagataa tgatgatgct atagaactca ttaccttaga agtcaatcct ccacctattt
   107581 tatatacctt attagctgat ttagtttcta aattcgtttt atgatatgca gatacatacg
   107641 tctttggtgt tataagtatt ggcgatttta aactagcagc caatggacct gctgctaaag
   107701 catcaacaag tacatctgat ttagctacta aaatagcttc taactcatca tctgtataga
   107761 atttttttat tacatttgca tttgtttcat gtctatctgc tccatacacc ctattattag
   107821 taacgttatc cttagttatt ccatttacct tgtttataac atttgttgat atcatttgag
   107881 gaccacctat aaaataagca ttttgtaaat cctcattctc tagccattta
//
LOCUS       DAMKOJ010000004        79693 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000004 DAMKOJ010000000
VERSION     DAMKOJ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 79693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79693
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.004"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(40..813)
                     /locus_tag="PC592_000346"
     CDS             complement(40..813)
                     /locus_tag="PC592_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HDF4054369.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(813..1199)
                     /locus_tag="PC592_000347"
     CDS             complement(813..1199)
                     /locus_tag="PC592_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4054370.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDMFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1224..1541)
                     /locus_tag="PC592_000348"
     CDS             complement(1224..1541)
                     /locus_tag="PC592_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HDF4054371.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHGLIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     MEG"
     gene            complement(1553..1813)
                     /locus_tag="PC592_000349"
     CDS             complement(1553..1813)
                     /locus_tag="PC592_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDF4054372.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1813..2109)
                     /locus_tag="PC592_000350"
     CDS             complement(1813..2109)
                     /locus_tag="PC592_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF4054373.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2178..4604)
                     /gene="gyrA"
                     /locus_tag="PC592_000351"
     CDS             complement(2178..4604)
                     /gene="gyrA"
                     /locus_tag="PC592_000351"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDF4054374.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDIAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFNLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4622..6523)
                     /gene="gyrB"
                     /locus_tag="PC592_000352"
     CDS             complement(4622..6523)
                     /gene="gyrB"
                     /locus_tag="PC592_000352"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDF4054375.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESH
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPVTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPAKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6524..7639)
                     /gene="recF"
                     /locus_tag="PC592_000353"
     CDS             complement(6524..7639)
                     /gene="recF"
                     /locus_tag="PC592_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDF4054376.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRVNKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRTFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKSIHVDEALLDVYDDTLARYGSYIYILRRDFIKKIASISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEISHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7656..7862)
                     /gene="yaaA"
                     /locus_tag="PC592_000354"
     CDS             complement(7656..7862)
                     /gene="yaaA"
                     /locus_tag="PC592_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDF4054377.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(7999..9105)
                     /locus_tag="PC592_000355"
     CDS             complement(7999..9105)
                     /locus_tag="PC592_000355"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDF4054378.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9347..10669)
                     /gene="dnaA"
                     /locus_tag="PC592_000356"
     CDS             complement(9347..10669)
                     /gene="dnaA"
                     /locus_tag="PC592_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDF4054379.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11325..11462
                     /gene="rpmH"
                     /locus_tag="PC592_000357"
     CDS             11325..11462
                     /gene="rpmH"
                     /locus_tag="PC592_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDF4054380.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11540..11884
                     /gene="rnpA"
                     /locus_tag="PC592_000358"
     CDS             11540..11884
                     /gene="rnpA"
                     /locus_tag="PC592_000358"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDF4054381.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEVYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11916..12167
                     /gene="yidD"
                     /locus_tag="PC592_000359"
     CDS             11916..12167
                     /gene="yidD"
                     /locus_tag="PC592_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDF4054382.1"
                     /translation="MNKIIYILKEISRYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFIKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            12199..12906
                     /locus_tag="PC592_000360"
     CDS             12199..12906
                     /locus_tag="PC592_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF4054383.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYILAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12875..13504
                     /locus_tag="PC592_000361"
     CDS             12875..13504
                     /locus_tag="PC592_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HDF4054384.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKIKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13616..14995
                     /gene="mnmE"
                     /locus_tag="PC592_000362"
     CDS             13616..14995
                     /gene="mnmE"
                     /locus_tag="PC592_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDF4054385.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGERALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDKENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKDKTDELKKEIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVERSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15093..16985
                     /gene="mnmG"
                     /locus_tag="PC592_000363"
     CDS             15093..16985
                     /gene="mnmG"
                     /locus_tag="PC592_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDF4054386.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKEQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQVRRT
                     RGGKGE"
     gene            16978..17697
                     /gene="rsmG"
                     /locus_tag="PC592_000364"
     CDS             16978..17697
                     /gene="rsmG"
                     /locus_tag="PC592_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDF4054387.1"
                     /translation="MNNMELLKNGIEGFNIDTNDSMLEKFKIYREILIDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDRLELTLLDS
                     LNKRINFLEEVSRVLELDNIKFIHGRAEDFGKNENYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEIDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17860..18645
                     /gene="noc"
                     /locus_tag="PC592_000365"
     CDS             17860..18645
                     /gene="noc"
                     /locus_tag="PC592_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDF4054388.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKIQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18780..19553
                     /locus_tag="PC592_000366"
     CDS             18780..19553
                     /locus_tag="PC592_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF4054389.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19555..20418
                     /locus_tag="PC592_000367"
     CDS             19555..20418
                     /locus_tag="PC592_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF4054390.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETPEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLADSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20451..21593
                     /locus_tag="PC592_000368"
     CDS             20451..21593
                     /locus_tag="PC592_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF4054391.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKSLEKKGIENTVVKCDYEGFLNYEDLEKAIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYNIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRAAVIALNIGNMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21729..22304)
                     /locus_tag="PC592_000369"
     CDS             complement(21729..22304)
                     /locus_tag="PC592_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HDF4054392.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGNDTSKKETKSNTNVEQ
                     PKEENSTEKEVPNNKTKPTPKEETKTQSATIYSFDVDKTDLIENKVDLSKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAEALMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22564..23856
                     /locus_tag="PC592_000370"
     CDS             22564..23856
                     /locus_tag="PC592_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF4054393.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEITLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            23961..24563
                     /gene="yedF"
                     /locus_tag="PC592_000371"
     CDS             23961..24563
                     /gene="yedF"
                     /locus_tag="PC592_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDF4054394.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDKLEEGVVVTIVDNETAKENV
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNIVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24636..24899
                     /locus_tag="PC592_000372"
     CDS             24636..24899
                     /locus_tag="PC592_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDF4054395.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILIENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24914..25099
                     /locus_tag="PC592_000373"
     CDS             24914..25099
                     /locus_tag="PC592_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDF4054396.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25202..26398
                     /locus_tag="PC592_000374"
     CDS             25202..26398
                     /locus_tag="PC592_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF4054397.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDADGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26612..26890
                     /locus_tag="PC592_000375"
     CDS             26612..26890
                     /locus_tag="PC592_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDF4054398.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            26927..27361
                     /gene="ssb"
                     /locus_tag="PC592_000376"
     CDS             26927..27361
                     /gene="ssb"
                     /locus_tag="PC592_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF4054399.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27380..27607
                     /locus_tag="PC592_000377"
     CDS             27380..27607
                     /locus_tag="PC592_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDF4054400.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27750..28070
                     /locus_tag="PC592_000378"
     CDS             27750..28070
                     /locus_tag="PC592_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF4054401.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28078..29034
                     /locus_tag="PC592_000379"
     CDS             28078..29034
                     /locus_tag="PC592_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDF4054402.1"
                     /translation="MNNKIRLSKAMSIIILAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFSDISYALNICIMYSLPGVVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNTFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSRLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29045..31039
                     /locus_tag="PC592_000380"
     CDS             29045..31039
                     /locus_tag="PC592_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDF4054403.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRHHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31040..31489
                     /locus_tag="PC592_000381"
     CDS             31040..31489
                     /locus_tag="PC592_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDF4054404.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRALGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31508..32836
                     /gene="dnaB"
                     /locus_tag="PC592_000382"
     CDS             31508..32836
                     /gene="dnaB"
                     /locus_tag="PC592_000382"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDF4054405.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33041..33349
                     /locus_tag="PC592_000383"
     CDS             33041..33349
                     /locus_tag="PC592_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054406.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKSEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33431..34720
                     /locus_tag="PC592_000384"
     CDS             33431..34720
                     /locus_tag="PC592_000384"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDF4054407.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKMDNISTENIKISNRA
                     HVIFPYHKELDVLSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAIRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35051..35126
                     /locus_tag="PC592_000385"
     tRNA            35051..35126
                     /locus_tag="PC592_000385"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35084..35086,aa:Lys,seq:ttt)
     gene            35133..35207
                     /locus_tag="PC592_000386"
     tRNA            35133..35207
                     /locus_tag="PC592_000386"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35166..35168,aa:Glu,seq:ttc)
     gene            35212..35287
                     /locus_tag="PC592_000387"
     tRNA            35212..35287
                     /locus_tag="PC592_000387"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35245..35247,aa:Val,seq:tac)
     gene            35321..35395
                     /locus_tag="PC592_000388"
     tRNA            35321..35395
                     /locus_tag="PC592_000388"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35353..35355,aa:Thr,seq:tgt)
     gene            complement(35777..36769)
                     /locus_tag="PC592_000389"
     CDS             complement(35777..36769)
                     /locus_tag="PC592_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4054408.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSLDDE
                     ISKIGLRLAKIVLLNPKSKDEIVKKTKENIESLKLKKEKLLTENNIPLDYLEIKFQCV
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKSSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDSNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36778..37836)
                     /locus_tag="PC592_000390"
     CDS             complement(36778..37836)
                     /locus_tag="PC592_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF4054409.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNSSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSVKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIIKACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            37961..39424
                     /locus_tag="PC592_000391"
     CDS             37961..39424
                     /locus_tag="PC592_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HDF4054410.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNIEYINNTKSNIDKIYLHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSVGRFGYGENTINVTNWFPIVCVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLVNDKHDNKKMLYEIEAKNVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFRPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39509..40306
                     /locus_tag="PC592_000392"
     CDS             39509..40306
                     /locus_tag="PC592_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4054411.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     IDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTENDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSNAGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40319..42421
                     /locus_tag="PC592_000393"
     CDS             40319..42421
                     /locus_tag="PC592_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HDF4054412.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     VYQEYLSSLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELDSYIEIFKTKWLFTSIIVSMTSSVLFVRLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNRMGTNLMSAL
                     LFIFLMHFMWFFGIHGGNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGFLLCLVIAIFLSEKRINVRKLAKIASIPAVFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYISTGSIRGSLLQLFNLCVG
                     VMIYIPFIKISQNRYTYMFKNNIENLTKLVKRYELTGEQPNFLNHNGKIGSISKMLAS
                     DLKFAMKRGEIEIFYQPQVNYNGDVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACVDLKKSEKLLRNSVKFSVNISPDQLDEPKLPEQIKNIISSNDINPNM
                     LGIEITEQVALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENMDQRDKLYRLGCEIYQGYYYS
                     KAIPFEEFIEYANQEREI"
     gene            42489..42968
                     /gene="rlmH"
                     /locus_tag="PC592_000394"
     CDS             42489..42968
                     /gene="rlmH"
                     /locus_tag="PC592_000394"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDF4054413.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSSKEMEIIKDKEGKKILGKVKHNSYVIALAIDGKSLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43117..43428
                     /locus_tag="PC592_000395"
     CDS             43117..43428
                     /locus_tag="PC592_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054414.1"
                     /translation="MIKIMLSCSAGMSTSLLVTKMEIAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43476..43793
                     /locus_tag="PC592_000396"
     CDS             43476..43793
                     /locus_tag="PC592_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF4054415.1"
                     /translation="MDEKIIEISFNIIGYAGKGKGLAFEAIKEAKNGNIEKAKDLLKE
                     SKEVINKAHKYQTELIQNEASGNKTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44005..44706
                     /locus_tag="PC592_000397"
     CDS             44005..44706
                     /locus_tag="PC592_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4054416.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTSSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLDKDILLGRKRKTYDESDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            44927..46228
                     /locus_tag="PC592_000398"
     CDS             44927..46228
                     /locus_tag="PC592_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4054417.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKATLDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVESVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISAALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSSHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGIIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46366..47460
                     /locus_tag="PC592_000399"
     CDS             46366..47460
                     /locus_tag="PC592_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF4054418.1"
                     /translation="MERRLGISVYPEHSKMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILEISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATSTKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVDRYQVVFNVVAKEKTSEIEKTIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTNIFKRGDVVIGNDDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            47462..48595
                     /locus_tag="PC592_000400"
     CDS             47462..48595
                     /locus_tag="PC592_000400"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDF4054419.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSNMMNIDEDELKNAVKKYKDFVVGIKARMSK
                     SVVISNDIKPLKVAKRIKNELNLPMMVHFGSSPPMIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDVAMKSKDAEIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIINKVTKNAAKAISLKNKGLIKEGYDADLTIFDV
                     VDEEKELQDSLNKSVITSISIKPRAVVVNGEYLNIGKSIRENE"
     gene            48613..49721
                     /locus_tag="PC592_000401"
                     /pseudo
     CDS             48613..49721
                     /locus_tag="PC592_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420588.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
     gene            49786..50526
                     /locus_tag="PC592_000402"
     CDS             49786..50526
                     /locus_tag="PC592_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDF4054420.1"
                     /translation="MNCTPQYYKNRVCLNVLAGSIKNAKEVYDACDGHILVGLLSKNY
                     STVEVAIEDIKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQDDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVHIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGDTKVEDIEVLYKIMKELLG"
     gene            50531..51523
                     /locus_tag="PC592_000403"
     CDS             50531..51523
                     /locus_tag="PC592_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDF4054421.1"
                     /translation="MNILAFGEIMMRLSVPGYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANVRKLGVKDDFITYGGNHIGVYFLESGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEGMDVVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERSYDDLVNDYKKILPYCHGLFASCRDINKILNIDNLDIKSSSE
                     LIKKEFDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESKEYKLEIYDRVGAGDGYVA
                     GIIYSYLENMSNEDIVEFGVASSVLAHTTYGDNSLVSTSHVLRLMNNEKIDILR"
     gene            complement(51711..52592)
                     /locus_tag="PC592_000404"
     CDS             complement(51711..52592)
                     /locus_tag="PC592_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4054422.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKSLEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEHK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVASNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52865..54253
                     /locus_tag="PC592_000405"
     CDS             52865..54253
                     /locus_tag="PC592_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054423.1"
                     /translation="MEDKFYAKGKGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLVYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLIILDVEDLTRPKCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKSWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFLGPRLAVTEDIIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54281..55234
                     /locus_tag="PC592_000406"
     CDS             54281..55234
                     /locus_tag="PC592_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF4054424.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSICVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNVIGTKVAEATGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTKLAQVRQLGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYIEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTPEFKERKTAYNFIEPLTKEKQAGASLR"
     gene            55287..55511
                     /locus_tag="PC592_000407"
     CDS             55287..55511
                     /locus_tag="PC592_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054425.1"
                     /translation="MNEKPSFKQIEIILVVICLVFAHYNVRLTPEFIAIIIPLYLSYF
                     IVSIIANQIAIKLLEIRQTREATSYNIGNG"
     gene            55504..56016
                     /locus_tag="PC592_000408"
     CDS             55504..56016
                     /locus_tag="PC592_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDF4054426.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMEYMNFNQNLELFLTLSILGFFAVVIAS
                     SFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAIAMAVGIWYVGVGVDLFTRY
                     ILSKDKKKLN"
     gene            56048..56902
                     /locus_tag="PC592_000409"
     CDS             56048..56902
                     /locus_tag="PC592_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HDF4054427.1"
                     /translation="MVMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDIENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGVSKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVA
                     ELWFEGEEEWYKAVVEEAKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57528..58049
                     /locus_tag="PC592_000410"
     CDS             57528..58049
                     /locus_tag="PC592_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF4054428.1"
                     /translation="MVLLIVDTQKLITNEELYNFNEFVVNLVKLIDTARKKYIEVIYV
                     RHDDGIDCELTKGKHGFEIYEEFKPCDEEKIFDKDVNSAFKETGLLEYLTNKNEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPSYANTTIDNSFMSAEQSYKYYNEFIWNGRYA
                     ECISLDETLKRMN"
     gene            58538..60619
                     /locus_tag="PC592_000411"
     CDS             58538..60619
                     /locus_tag="PC592_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4054429.1"
                     /translation="MDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKINDM
                     LKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKAERLLYMYLMLFIN
                     MEDISINHFINSIKVSRSTVNLDFKDLIPNLEKKGIEVKNNRINGYYLVGNEMEIRRV
                     LIKSIIETLSNEKSSRVFDIFIKEYNLDSFEEDKEIILKLIKKYEITFVEDRLIEFIY
                     IFIFLKARMYSTRIVTHENVDIPNIAVMSSMKEYKFAKELLETYESEDKIKSHNIMYI
                     SAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFRPA
                     YYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHFAT
                     LFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENMSEP
                     VDIVFTTNYNTEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEVMN
                     IIKKYANVTSESILSSELLTYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNWED
                     AIRQSASVLVENNKTTEGYVEAMINSAKASGPYIVITKHVALPHARPEAGSKEIAIGI
                     ATLDSPIEFGNDENDPVKYVFCLSAIDNNSHLRAMSELVELLEEEEFFKVLDSAKEPK
                     EIIDYIKTHEL"
     gene            60634..60921
                     /locus_tag="PC592_000412"
     CDS             60634..60921
                     /locus_tag="PC592_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054430.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIVKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKHLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            60948..62219
                     /locus_tag="PC592_000413"
     CDS             60948..62219
                     /locus_tag="PC592_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDF4054431.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFITAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNSSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            62276..62875
                     /locus_tag="PC592_000414"
     CDS             62276..62875
                     /locus_tag="PC592_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF4054432.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACNLIFEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTPAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKGTLETLKINGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIVLQSLSVALQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            62880..63764
                     /gene="dapA"
                     /locus_tag="PC592_000415"
     CDS             62880..63764
                     /gene="dapA"
                     /locus_tag="PC592_000415"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF4054433.1"
                     /translation="MKYKGIICAMITPFDENQNINSRATCQLIDYLIKNGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVIDLSKRMEAVGASALS
                     IITPYFVTPTQQELILHYETIANSVNLPIIMYNMPDKTGINIEPESVCKLSKIKNIVG
                     IKDSSGKLDNMKAYIEVTKNEDFSVFSGSDSLILDSLKAGSQGAVAATANFLTKIDIS
                     IYENFMRGDLEEAQKAQSSIEEFRRILKLGTIPSVLKKTIVLNGIDVGTARLPVIEPT
                     GDALEEIKNVVENYREMF"
     gene            63893..64525
                     /locus_tag="PC592_000416"
     CDS             63893..64525
                     /locus_tag="PC592_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HDF4054434.1"
                     /translation="MKKMNITKRMAECGALAIVREEKLNRACEIVEGCIKGGITVVEM
                     SYTLNNAGEIIQGLNKKYGEALCVGAGTVLDSETARHAILHGAQFVISPNYNEDVAKI
                     CNRYQIPYAPGCTSLTESVEALSLGAAFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINLENLHVWLENGVDVCGFGGLLTKGTVEDIAKNAKKIREIIKNIREV"
     gene            complement(64711..65988)
                     /locus_tag="PC592_000417"
     CDS             complement(64711..65988)
                     /locus_tag="PC592_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4054435.1"
                     /translation="MENTVKNSKIFYGWWILLACIIVMALGYAPIVSLASLFIKPITE
                     DLGFTRSAYTLSTAIISLMCMFMASITGKLMSTKHMHLIHVICVAGLSIFYGLYSLAT
                     SIFHFYVVSFFIGLFTYGATKMPVSILISNWFYEKRGLALSLSMAGTSISGTLLSPLV
                     VKLITNYGWRQTYVYLAIVMFLIMVPATIFIVRQFPSCKGLQPYGYDRHQDNTNKNTI
                     KNEWNISLKEAKKLPVFWTFTFGVTLILLTGCILGHIPAYLEDSGYNPSLTASIVSTY
                     LFIAIWGKVVLGHVFDKLGSKAGVLLGNICFIISIVCLLFIEFKPMLYLMTFFFGIGT
                     CIGTVTTPVLTSRIFGTKHYPEIYGFVASCTCIGSIIGTPAIASIFDLTGSYKMAWII
                     LIILSIIMTLALVYSINEGHKYRLKDVSQQTIK"
     gene            complement(65990..67180)
                     /locus_tag="PC592_000418"
     CDS             complement(65990..67180)
                     /locus_tag="PC592_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4054436.1"
                     /translation="MSDMFMNLAKQFESEIISWRKHFHENPEIGMELPNTVNFIQKKL
                     EEFNIEYKVGCNGYSITGLIGNKNSGKCILIRSDMDALPVIEQTELEFKSNNNYMHAC
                     GHDAHMAILLGAAKILKLKENELEGSVKLMFQPGEEVFEGAKAMISEGVLENPKVDSA
                     FGMHVVPTMPNKSVVYGKEFMSSCYGFKITIKGKGGHGSQPENCIDPINTGVHIYLAL
                     QELISRECPPQELATLTLGQFKSGEACNVIPNEAVLQGTLRTFSPTTRDLLINRINEV
                     VQSVSITYRCSADIEVLSNVPALICNDELNKKFMSYIYELDKNIKMSEFNHTMGSEDF
                     AYISEKVPTCFMYLGAGIEDTSKWYVAHNPKVMFNDKCLALGSAIYAQCAYQWLKNMS
                     KESL"
     gene            67365..68243
                     /locus_tag="PC592_000419"
     CDS             67365..68243
                     /locus_tag="PC592_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4054437.1"
                     /translation="MNLNYFQYLVEVANIGSISKAAEKNFVSQPYLSGIIKKMEDEVG
                     FLIFKRTNLGIELTEKGEIFINEAKKILIGIENIKNINTKNEEGLSIGMVYSLFFTKC
                     FLKFKKFKPTDLQDKVYEMSPMEIFKALIDNKIRLGLFSYATKKKDKYWNIAKKHHLK
                     CWSIYEDLHPYVIMSRSHPLALNDSITISDLNSNPYVVYDKSEFLIYLDMIGIRKHPD
                     LLLVSDRGSFSDAILDNNYLGITTYFSEINEQDNKFIYIKLEDCDETIGIGYAILDNY
                     KLSQREKDFIKFIKNK"
     gene            69022..71529
                     /locus_tag="PC592_000420"
     CDS             69022..71529
                     /locus_tag="PC592_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4054438.1"
                     /translation="MKEDIGLHRMCKEEQVTKNEVISEDILKSMSMGVSKHFLDDSFT
                     ILWGNTSFYQLFGYTEEEFLFKFSSLKDYYEQNLYNFESMKNHFLEAYHRGEKSTEYQ
                     ICISANNVDPVWVIMNGILIESEENEKSMVYILYSRINELEIKQEEASKMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKQSCNILQASVNELIGRKCYEVIQDRTSPCPFC
                     TNPYLKKNDVYEWEFYNKKLKRTFMIKNRMLNWKGRRARIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRVDARDYLTILWYNDIFLNMIEYTKEQFAEELDNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEARIYTRSREERIWTVTLCYVSGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQYISEKDALTGIYNRAETERQIKKYFEENLNSMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMCDSDVVGRIGGDEFTIFMKDISSVKDAEKKAEEL
                     LYMFRHLFQKEKSSLKVTCSIGIAIYPKDGTTFKEIYTRADKALYQAKNIGKNNYVIY
                     NQDSFKELEAFNCSSLGTVIDSEKQYAECPDNLTRYIFRMLYQTDNIDETINMILEVV
                     GKQFNVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNNNYQDYEDYEKLFGDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDKVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNKKFNQQMQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKLQIGQPCYLDAVDIHKISIAWNQKEAYLCISMI"
     gene            71872..74040
                     /locus_tag="PC592_000421"
     CDS             71872..74040
                     /locus_tag="PC592_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDF4054439.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKFNKNYSNWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGEFPN
                     TNTNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFDKISEVGESGILYISTQNKDT
                     INKILKELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSR
                     EASILRLNGYSKLDIITRVIRSILRIMILSSITSLLIYIIYILKLNLGVRACLYFVIF
                     SIICILINIFISILIVGFNIRSSKYVLTLNGKKPYGFVNIIHFTLKIVFVSFLILSIN
                     NCILNYNILQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKSLVE
                     EKDAFLIDTTNFEKLENGSYMYEINSKGKKPEVSQYGKNIKINKNYLKVNPIYSNGKE
                     IFNLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNEELNRDLNKTK
                     KSDLNVNIIYVDNNQSYFTYNSLVMDDNRNLINDPIAIVDIDNIDDSFYLSYISRCVY
                     FNSKKLDALADISKIIEAQGVEANIQSLRAVYNEYGLEINKLEKYLNSEIFTIIIIAI
                     SNLMITYNIVVSYYERNKYKLYIKKIFGYSATARSILLIISLILTNVIPIGIISTRVD
                     LSNNIVLFGLLILVVEVIISIILDKIISNSSFNKIIKGEH"
     gene            74045..74662
                     /locus_tag="PC592_000422"
     CDS             74045..74662
                     /locus_tag="PC592_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054440.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVESNLKIAL
                     KYQKNINRDEKINYVLESVGLGKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNNNGKTIVLVTHDLELSEQVDKIIKL"
     gene            74851..75195
                     /locus_tag="PC592_000423"
     CDS             74851..75195
                     /locus_tag="PC592_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDF4054441.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLELEGDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSAIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVIKKA"
     gene            75767..76633
                     /locus_tag="PC592_000424"
     CDS             75767..76633
                     /locus_tag="PC592_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF4054442.1"
                     /translation="MISIHKNIYDDKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCMNLQPDFKCSVHDNLMKRGFKGCTAYDCFGAGQKVAQVTYKGIDWMQSPELA
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKINLRIEETEKITNMSSEQIVDLD
                     IISHREKVNSLLLQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKTNLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PVSLIRPKYWGK"
     gene            76746..77150
                     /locus_tag="PC592_000425"
     CDS             76746..77150
                     /locus_tag="PC592_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HDF4054443.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNEYYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            77326..77775
                     /locus_tag="PC592_000426"
     CDS             77326..77775
                     /locus_tag="PC592_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4054444.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIKFLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKAFDRSEIDGQGNPFPILHMKLI"
     gene            complement(77932..78309)
                     /locus_tag="PC592_000427"
     CDS             complement(77932..78309)
                     /locus_tag="PC592_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF4054445.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLESNPNNPVMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSRETIEEISIKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            78571..79488
                     /locus_tag="PC592_000428"
     CDS             78571..79488
                     /locus_tag="PC592_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDF4054446.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYIYELMKPFEFKWKC
                     MNVPIVAKQKGGYDVIIASEMLGVLSPKDIDEKQKKNINMLSTDKIWNTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGIAENFAKWMFGEEMVGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVEEFWE"
BASE COUNT        30435 a         9564 c        13177 g        26517 t
ORIGIN      
        1 catctttaaa acagtaggtc aatacttttt tatatttttt tataaatttt tttcatattc
       61 ttttttcagc ttctctacta cctttttctc tagcctagaa acagtcattt gagatatccc
      121 taattcctta gctatactag attgtgtttt atcaaagaaa aatctatctt taaaaatttt
      181 aacttctaat tcatttaaag tttcaataaa cttattaata aaatcttcat actctatact
      241 tccaaagtta ccttcttctt taccaatctt atcaataaga gttatatctt tatcctctga
      301 atcatcatta cttgatgaat ccaaagacat tggttgatat ccataagaag cctccatagc
      361 ctctagaaca tcttcctcac taacgcctat ataatcagct atatctttta cctttggatg
      421 ctttttattt tcttgttcta atttaatctt cgcatcactt atctttttgc ttaattcctg
      481 tatccttctt gggactctaa gtgtccacac cttgtctcta aaatactttt ttatttctcc
      541 tactatagtt ggtgtcgcaa agctggagaa ctcaaaccct ttctcaacat catatctatc
      601 aatagcataa attaatgcca atgaagcaac ttgatatata tcttcaaaat caacaccttt
      661 gtttatatac ttcttagcta acaatcttgc taaatacaga tgtctttcaa taagaatatt
      721 cctaatatct acatttttat ttttattata taaattaaat agctcttttg tatccatatt
      781 taggtaatgt gtagcattag ctacattttt cattaaatat caactcctaa atatttagtc
      841 atttttattt ttgtcccctg attatgttct gattcaatat ctacatcatc cattaaagtt
      901 ttaattataa ataatccaag accactctct tttggattct ctaaatctgg tgtacttatt
      961 gagctaacat catatccttt tccattatct tgaatttcta tattaattgc attatctaaa
     1021 atattaaata ctatattaaa catatcatct ttactatgtt ttattgcatt tgtacatgct
     1081 tcagatactg ctacttttat atcttctata tcatctattg gaaaacccat cttattggca
     1141 attccagagg ctgttaatct tattatacta acataatctg gatttgtagt aatttccatc
     1201 tttatagtct cacaagccaa agtttatccc tccattttaa atattttatc tagacctgtt
     1261 atagtaaaaa tctttcttac attactctta ggatttacta tgtatatctc tttttcattt
     1321 atttttaatt tttttaatac acctatcata gctcctaaac ctgttgagtc tatataatct
     1381 agatctttaa gattaatctt tacatctaac atattctttt ctattaaacc atgtaagtgt
     1441 tcctttagtt tatctgctgt agaaacatca agttctccat caaggcaaac attccaaaat
     1501 ttattttgtg aatctaaatt tgaatcaata ttcatagaca tgtaaaaacc tcctatttcc
     1561 ttttaataat tttaaatata tttcctatac tcaatatttt attaattaca taaactatat
     1621 catctattcc ctttgatatt gatgatgcat tttcaacaat atcttgtata tgtctttcat
     1681 tataatctac aatcttatat gccttttcaa caactttatt tatgctattt agagttttag
     1741 ctaaataaat tgctactatg agagcagagc ttcctactaa cactgctcca atctgccacc
     1801 cccatgcatt cattagttaa catctccctc atcatcaaag cttttactta ttactatatc
     1861 ttcttctgaa atctttatat cttcttcatt attatcatcg tctactaaat ttattattct
     1921 ctctttaaca tcattaaatg tttcatgtag aacttctttt ggattttctt taacatcatt
     1981 aaacttctct tttgtttctt ttcttagttc agaacctttt ttgggtgcaa aaaacatacc
     2041 aaatataaac cctaaaatag ctcctaataa taaaaatcca ccttttttac aacttctttt
     2101 attgcacata acaattactc ctttcaattt taaattttta tctaactaca ttatacaaaa
     2161 agaataggat atttatccta ttcttcttca atatttattt tggcaatcga aactacatta
     2221 acttcatcat tcgtcttcat taatttaaca ccacttgtaa ctcttccaaa cagtgatatt
     2281 tcattgactc ttattctaat aagaactcca tcagaattta taatcattat ctcatcatct
     2341 tcattaacca tatctgcacc tacaattgta ccagtctttt cagagatatt ataagtttta
     2401 attcctttac cagctcttat ttgacttcta tactcttcta tatttgtcct ctttccaaaa
     2461 ccattcttac ttacaactaa cacatctgta cctttactgc aaaggttcat agacacaaca
     2521 aagtcttctt tacttaaagt tatacctttt acacccatgg ctgttctacc catatatctt
     2581 atatcatttt catcaaatct tatagacata ccttctttag ttactaaaag tacttcttgc
     2641 tttccgtctg taagttctac tccaataagc tcatcatcat ctcttaagcc tatagcaata
     2701 agacccgatt tatttatatt tttgaactct tccctcttag tcttcttaac aatacctttt
     2761 ttcgttgcaa gtaataaata ttcattttca tcattaccat caataggtat tagagtagca
     2821 attttctcat ctgctgacaa ttgaagtaaa ttcactatag cagttccttt agcctgtctc
     2881 ttaccttcag gtatttcata tgcatttaat ttaaatactc tacctttatt tgtaaagaat
     2941 aatagtctac tatgagtagt tgtagttact aagtgtctta caaaatcttc ttctctagtt
     3001 gtaagtgctg aaatacctct tccacctctt ttttgactct tataagtatc agatggaagc
     3061 ctttttatat atccaaagtg agtaagagtt attgctattt cttcatcact tataagatct
     3121 ctcatatcta tttcgccttc agcatgtctt atttctgttc ttctctcatc agagtaattt
     3181 tcttttatta ttgtaatttc atcctttatt acattcaaaa gtaatctttc atcagctaaa
     3241 atttctttta atctatttat cttcttgatt aagtcttcat attcagcttc tatcttatct
     3301 ctttctaaac ctgtaagtct ttgaagtctc atatctaata tagcttgtgc ttggatttca
     3361 gttaagttaa atttttctat taaacctaac ttagcttctt gcccagtctt tgaagctctt
     3421 atcaagctta taacagcatc tatattatct aaagcaatct ttaatccttc taaaatgtgt
     3481 gctcttgctt cagctttatt tagttcaaac ttagttcttc ttgtaacaac atcttcttga
     3541 tgtttaatat aatgatataa tatttgtttc agatttaaaa ctcttggctg accatctaca
     3601 agtgcaagca ttattatact aaaagtatct tccatttgag aatgtttata taaattattt
     3661 aatactatat tagcattagc atccctcttt aattctataa caattctcat accatttcta
     3721 ttactttcgt ctcttaggtc tgatatacct tctattctct tttctttaac taactcagct
     3781 attctctcaa ctagtttagc tttatttact tgataaggta tttctgtaac tattatttgc
     3841 tgttttcctt ttggtagttc ttctataaaa gctctagacc taactttaac ttttcctctt
     3901 ccagttctgt atgcttctgc tatactttct ttccccatta taattgcagc tgtagggaaa
     3961 tctggtcctt gaacaaattt tattaaatca tctacactac actctggatt atctatcaaa
     4021 tatacagttg catcaattac ttctgctaag ttatgtggag gtattgaagt tgccatacca
     4081 acagctatac catttgagcc atttactaat aaattaggat atctcgctgg caacactgaa
     4141 ggctctttta atgactcatc aaagtttggt ttaaagtcta cagtttcctt ttcaatatct
     4201 ctcagtagtt ctaatgataa tttactcatt ttagcttctg tataacgcat agcagctggt
     4261 gaatctccat caacagaacc aaagttacca tgaccatcta ctaaaagtgc tctagttgaa
     4321 aaatcttgtg ccattcttac catagcataa taaacagcaa tatctccatg aggatggtat
     4381 ttacctaaaa cgtccccaac aatacgagct gacttcctgt atggtttatc tggagttaaa
     4441 tttaactcac tcattgaata tagtattctt ctatgaactg gctttaaacc atctctaaca
     4501 tcaggaagag cacgtccagc tatgacactc attgaataat caatataaga ttttttcatt
     4561 tcttccgcta tttcaatagg gagtattttg ttattttctt ccatgtatac taatcccctc
     4621 tctatatatc taagtttcta acaaatcttg cattttcttc tataaattct tttcttggag
     4681 caaccttatc acccataagc attgaaaata cttcatctgc aattgcagca tcctccacag
     4741 taacttgtaa taaagttctt gtttcaggat tcatagttgt ttcccataat tgctctgcgt
     4801 tcatctctcc aagacctttg tatctttgaa gttcaacacc atttcttcca atttcatcta
     4861 ataagatatt taactcttta tctgaataaa catagtgctc cttcttttgc tttgttactt
     4921 tatataaagg tggttgtgct gcataaacat acccttcatc tataagaggt ctcatatatc
     4981 taaagaagaa tgttaataat aaagttctta tatgggctcc atctacatcg gcatcggtca
     5041 taattataat tttatgatac ctagccttat ctatatcaaa atcttctcca ataccacaac
     5101 cataagctgt tatcatattt tttatttcat ctgaagataa tatcctatct agtcttgact
     5161 tctcaacatt aagtatttta cctcttaatg gaagtatagc ttgactattt ctgtctctac
     5221 cttgcttagc tgaacctccc gccgaatctc cttcgactaa aaatatttca cttttagctg
     5281 gatctttttc tgcacaatct gcaagttttc caggtaaaga tgtactttct agtacacttt
     5341 ttctccttgt taattccctt gctttttttg cagcttctct agctctttgt gctcttaagg
     5401 ctttatcaac tattattctt gctgttactg ggttttcttc taggaaagaa cctaattcat
     5461 caactgttac actatcaact atgcctctca taaagctatt tcctagcttt gttttagttt
     5521 gaccttcaaa ttgaggttct ggtaatttaa ctgatactac tgctgtaaga ccttctctta
     5581 tgtcttcacc aagtagatta acatcatttt ccttcaaaaa cttatttctc ttagcataat
     5641 catttacagt tttagtaaga gctgctttaa atccacttaa atgagaacca ccttcgtgtg
     5701 tatttatatt gtttgcaaaa gaatatatgt tctctgtata accatccgta tattgcatag
     5761 ctagttcgac aaaacaatca tcaacctttt tatctatata aactatgtca tcatgtatac
     5821 cagttctaga tttatttaaa tacttaatat attctaccaa accacctgta tagtgaaatt
     5881 cttttctttt ttcttgtcct tctcttttat cttcaaatac tatttttatt cctttattca
     5941 agaaagaaag ctctctaagt ctatattcca atgtttcata tttaaactct atttcatcaa
     6001 atattgtctc atctggcata aattgaatca ttgttccttt atcgtgagat tctccaacta
     6061 cttcaagctt agatgttggt aatcctttct catatgtttg cttatatatc tttccattta
     6121 agtaaacctc tgctaccatc cattttgaca atgcattaac tacagaaaca ccaactccat
     6181 gaagacctcc agatacttta tatcctccgc ctccaaactt tcctcctgca tgaagattag
     6241 ttaatactgt ttctaaagtt gatttgccag ttttaggatg tatttcaaca ggtatacctc
     6301 ttccgttatc ttttactaaa acactgccat cttcattgat agatacatat atgtctgaac
     6361 aatatccttg taaagcctca tctatactat tatctacaac ttcataaact aagtgatgta
     6421 aacctctagg gcttgtacta ccaatataca tacctggtct ttttctaacg gcttctaatc
     6481 cctctaatac ttgtatctga cttgcaccgt attcttgttt catttaattt cctccattct
     6541 ctatgctaat aacatcgcca ttttcaatat taaatattgt aacatttttt tcatcaaata
     6601 tttttttatg tgaaatctca gcacttgtta taaacatttg aacattgctt aaattattta
     6661 ctaaaagttt ttgtcttgct tcatctaact cactaaaaac atcatctaaa attaacactg
     6721 gatactcttc aacctcattt tttattaatt ctatctctga taactttaat gatattgaag
     6781 cagttctttg ttgaccttgt gaaccaaaaa gtcttgcatc taaatcattt atgaatatat
     6841 ttaagtcatc tttgtgtata ccatatctgg tagtcttaga ttctatatca ttaggcctat
     6901 tcgatgacaa cttggctaaa aatttattat atactgtatc tatagtatct tcgtcagtta
     6961 tatttatttg atttttgtat cgaattgata atctttcaac tccattagtc aaattcatat
     7021 gcatattctc agatatacta gctatctttt ttataaagtc tctacgcaaa atataaatat
     7081 aacttccata ccttgctaat gtatcatcat atacatctaa taaagcttca tcaacatgta
     7141 tacttttaag caccctactc ctttgagaaa gtgttttatt ataattggta agatatttat
     7201 aatatttagg tataatctga ctaatctctt tgtctataaa tgtccttctt tctttaggac
     7261 cctctttaac caacctcaaa tcctcaggag aaaatataac aacatttaag ttgccaagca
     7321 gttcttgtat cttttgcaaa ggaactttat ttactcttat ccccttttta tcttttccaa
     7381 taattagctc tattagacta tatttattat attttgaaaa acttcctcca atatataagt
     7441 tttcactatt aaatctaacc atttctttat ctttgttagt cctaaatgat tttccaaaag
     7501 aaagcatata aatagattct actatatttg tctttccttg accattttta ccaacaagta
     7561 gatttacttt cccattaaat tccagatgca actttttata atttctaaaa ttaacaagtt
     7621 gcaaactttt aagtttcaca aaaagttctc cttttttaca atacttttat tttagttcct
     7681 tctatttcaa ctatatctcc tgattttatc ttttttcctc ttcttaattc tatttcatca
     7741 tttactgtca ctaaaccttc ttgaattaaa aattttgcat gacctcctgt tgatgcaatc
     7801 tctgctaatt taagaaattg atctaacttt atatattctg attctatagt tatttcagtc
     7861 ataatagttc ctccttgtca ctattttaaa caaattccta ttgatacact aaaagtatat
     7921 tataccataa atatgcttat aaaaggagtt gtctaagatt agaaaaattt tctacaaaag
     7981 acaactcctt catgtctgct atatatttga tgatattctt actggaagca gtaagtaaat
     8041 ataattaaca tcatctgttg gtttaattat acaaggattt acatttgtag taaattctat
     8101 aaagatttcc tcattatcta tatttttcaa accttcaata aaatatctag aattgaaagc
     8161 tatgtctaga taatctccat ctaaatctat ttcaacctct tcatacacat ttcctttttc
     8221 tgtattagaa gtaattgcca ttaccttatc tcttatagat aactttataa gattattttt
     8281 ttctgactga gacaataaag acgctctctc tatactattt aaaagctcct tagtgtttaa
     8341 tttaactctg ctgttatgtt ctcttggcaa taacttttta taatcaataa aatctccttc
     8401 aagtaatctt gtgataattt tagtatcatt aattataaaa atagcatttt tttcgttaaa
     8461 cccaacttta acattatctt ctccagaaag caaactattt acatctataa gtgtctttcc
     8521 aggaattatg acttttatat tttcagttaa actatcaact gaacaacttt ttacagctaa
     8581 tctatatcca tcaattgcta ctaaatttaa gtttctatct acaatttcta aaagttctcc
     8641 cattaaaaca ggctttgttt ggtcctgtga gatagcaaat acggtttgtt taatcatatt
     8701 ttttaagatt tcttgaggta tactatataa atcttcttca tttaattctg gtaatttagg
     8761 aaattctttt gctgcatacc ctttaatttt aaatcttgaa tttacacaat ttatgtaaat
     8821 attattttct gaatcagttt ctatctcaac gaaagaatct ggtaattttc taattatatc
     8881 tccaaatagc cttgcatcta caacaacatc tcctttttct atgatttctg cttgtacata
     8941 agtttctatt cctatttcag catcatatcc agtaagtttt aattgacctt cttctgtaga
     9001 tataagtata ccttttaata attctattgt tgtttttcca ttaatagctt tttgagcaat
     9061 tccaattcta tttgctagga ttttttgatt acaaattatt ttcaatgtgg ataacctcct
     9121 ctggcttttt atatataaaa ataagttaaa atcatagtag taatagtagt aggtgttgtt
     9181 gataatgtta ataagtatgt ataacattat aaatacaaag atattaacat gtgtataaga
     9241 tgttaatatc tttgttattt tagacttgat aatttgttaa tactttttgt tcaaaaaaag
     9301 tattaacagg ttattcaaga gatataaaca tacaattgtg tataaattat cccttcaaat
     9361 ctgatataat tttgtctatt ttagtcttaa tttcttcact ttcttctata tccttagaca
     9421 ctttgtcatg agcatgaatt actgttgtat ggtctctacc tccaaactct tcacctattt
     9481 taggaaggga taaatcagta agttcgcgcg ttaaatacat agctatctgt cttggataag
     9541 ctattgaacg tgttcttttt ttagaattaa aatcttccat ctttaaattg aatacagaag
     9601 atactttttc ttttattctg agaacattta tttcttcatt tttagaagtt gttataatat
     9661 cttttaaagc ttctgtagca agatcaaaag atattaccct attactaaga gaagaataag
     9721 caactactct agttaatgca ccttctagtt cccttatgtt tgacttaata ttttttgcta
     9781 tatatgacat aacctcattt ggcacatcta tacgttctag ttgagccttt tttctaagta
     9841 tagcaattct tgtctcaaag tctggtgctt gaatatcagt tataagtccc atttcaaatc
     9901 tcgatcttag tctatcttct agtgtaggta tatcttttgg cggtctatca ctagatataa
     9961 ttatttgttt gtttgcttca tgaagagtat tgaatgtatg gaaaaactct tcttgagttc
    10021 tttcttttcc tgctataaat tgaatatcgt cgattaataa tacatctacg tttctatatt
    10081 tattcctaaa ttcttcgttt ttgtcgtctt ttatagagtt tataagttca ttagtaaatt
    10141 tttctgaaga aacgtaaact acttttgaat cttttttttg actaacaata tgatgaccta
    10201 tagcatgcat taagtgagtc ttacctaatc ccactcctcc atacaaaaaa agtggattgt
    10261 aagctttagc tggagattct gcaactgcaa cacatgcagc atgtgcaaat ctattgctat
    10321 taccaataac gaacgtatca aatgtgtatt ttggatttag attagggtaa agaactctat
    10381 aatttaaatc tgtactatca gaatttaaat cagcaacttc tttttcgctc aatacaaatt
    10441 taatattata tttttttaat gacagctgac taatagcatc ttcaattaaa tgtaaatatc
    10501 tattctctaa gatatcttta ttaaaatcac taggagccag taatattaaa tcattaagat
    10561 gtatttttaa tggtacgatg tttttaaaaa aggtattaaa acttaccgaa gttaagtcac
    10621 cttttattaa ttgtagggtt ttgtcccata aagaaactat atccataata taaacctccg
    10681 aacagaataa ttaatatttt ccacaaagtt attaacagaa aagcaaaaat atatataaat
    10741 tttacagaat aactaaattt atggataatg gtgttgataa attaataata gtataaatta
    10801 ttaaaaaaat atgaaaagat ataaacaata tgtagataaa gttataaata acataaacat
    10861 acaataaatg gtgattataa ctagagtatt gtcagtaatc ttaaaagtta tacacaaaag
    10921 tatccacaag ctgtgaataa tttctaataa gttgataaca tttatgcaca ttatcaacaa
    10981 gtatatttat aatatcaaaa tatatgtcaa acttcaatga tttgtaacta atttatccac
    11041 aatattaact aattgttgat aaaaatataa acatgttaaa attactttat ttgtgtatat
    11101 aattgaaaaa aataatttag aataaaatta aatagatttt tactagtatt ttcaataaaa
    11161 aaaatacata atatatatat ggtagatttt gtgatataag cgtcccaaaa actcgttgac
    11221 aacagtagta aaagtattta taattatatg tgttatgttt actttgaggg taaagttatt
    11281 atttttataa acggaaaata aaatctgaaa ggcggtgcaa aataatgagt aaaagaactt
    11341 atcaaccaaa aaagagacaa agaagtaaag aacatggttt cagaaaaaga atgaagacgt
    11401 ctaacggaag aaacgtgtta aagagaagaa gagctaaagg aagaaataga ttaactcatt
    11461 aattacaaaa gggccgctgc aaaggtggcc tttttgtgta aataattaca attcatagct
    11521 gtgtttatgg aggttaacta tggactttaa taggactaaa gggttgaaaa aagactctga
    11581 ttttagaaaa gtatataaac acggcaaatc ttttgcaaac aaatatttag taatatatat
    11641 acttaaaaat aaatcagatt atagtagagt aggtatttct gtttcaaaaa aagtaggaaa
    11701 agctattact aggaatagag taagaagatt aataaaagaa gtctacagat taaatattga
    11761 tgaaaaaatt aagcctggat atgatatagt atttatagca agagtatcta gtaaggatgc
    11821 tacttttaaa gacatagaca agtctataaa aaatttagtt aaaagaacgg atatttctat
    11881 ttaattgtat gctataaata tggaggttaa tgactttgaa taaaataatt tatatattaa
    11941 aggaaataag taggtattta tcgaatttat gtatttattt agtgagattt tatcaaaagt
    12001 atatatctcc cttaaaggga cctacctgta gattttatcc aacttgctca caatattcaa
    12061 tagaggcgtt taagaaatat ggatttataa agggtatgta tttaacgata agaagaattt
    12121 taaaatgtca tccttttcat ccaggaggtt acgaccctct aaaataaaag agagtaacta
    12181 ttaggaggta taaaaaaatt gaatataata ggaaatttct taggattgat tcttaaggta
    12241 atatttgaat ttgttaatca ttatggtatt tctataatac tttttacgat acttgtaaag
    12301 attattttat taccattgac aattaagcag actaagtcaa caaaggcaat gcaagatata
    12361 caacctcgta taaaagagat acaagaaaaa tataaaaata agccagaaaa acaaaatgaa
    12421 gaaattgtta agttatatgg agaagctaaa attaatccac tatctggttg tttaccttta
    12481 ttaatacagt ttcctatatt aataggatta tttagcgttt tgagagagcc agttgctcat
    12541 ggcgtttttg caaacaaagc tgcattttta gcagctgaca atgggttttt atggataaaa
    12601 agcttaacat caccagatta tatattggca gtattttcag gagcaagtgc atatgtcatg
    12661 caaaaagtaa tgacaccaaa agatcagtta caaggctcta tgaaagtaat gacatatgta
    12721 atggcaggta tgtctttcta ttggggattt atattcccag caggacttac attgtactgg
    12781 acagtaagta acttattctc aatagctcaa tattacttaa taatgaatcc tttaaaagct
    12841 aaactggctg ctaactctaa ggaggaaaaa gttaatgaga aaaagcctaa aattaataaa
    12901 aagtaagagt aaagaggaag ctataagtaa agctatagca gagttaaatt taaaagcaga
    12961 ggatatagag gtagaaatac ttgaaaatcc aagcaaagga tttttaggtt ttataggtgc
    13021 taaagatggt acttatgaaa tttttgttat cgagagggaa gtagatgtag ctaaaaattt
    13081 tatagaggta atgttgaaaa atgcaaatgt tgatgccaaa gtcaatgtat ctcaaaaaga
    13141 taatttaatc atggttgata ttgaaggcaa agaagctgca agtttaattg gtagaagagg
    13201 ggaaacttta gattctattc aatttttgac tggattagct cttaataaaa taaataaaga
    13261 ttctcataca agagtacttg tagatataga aaattataga tcaaaacgag aagaatcttt
    13321 aataagatat gctaataaag ttgctagaga agtagcgaaa acaagaaaaa ttaaaaaatt
    13381 agattatatg aatccatatg agagaagaat aatacattca gctcttcaaa atgacaaata
    13441 tgtaattaca tatagtgaag gaaccgatcc atatagaaga ttagtaattg agtgtaaaag
    13501 ataaagtcaa cctcctaaac attagggggt tttatttttt aatattatta aatcattaaa
    13561 gattggttaa atataaatct atatgtaaaa aattatgaat taagaggtga taaatttgtt
    13621 tatagatgat acaattgcag caatagctac agcacctgga gaaggtggta taggtatact
    13681 tagaataagt ggagaaagag ctttgaaggt tgcagaagaa atctttaaat ctatgtcggg
    13741 aaagagtatt gaagaataca ataagagaac attaatatat ggaaatatag tggataaaga
    13801 aaatataatt gatgaagttt tattggcata tatgaaagga ccaaactcat atacaggaga
    13861 agatgttata gaaattaatt gtcatggtgg atttatttcg gtaaagaaga tattagaact
    13921 aatactatca aaagatgtta gattagcaga agctggtgag tttactaaaa gagcattctt
    13981 aaatggaaga atagatttat ctcaagcaga ggctgtaatt gatgttataa aagccaaaac
    14041 tgatatagct catgaagttg ctcaaaatca attagagggc tctttatcaa agaagataag
    14101 agaattgaga gataaggtca ctgagatatt agctcatgta gaagttgcta tagattatcc
    14161 tgaagaagat attgagcata taacgtatca aactcttaaa gataaaactg atgaacttaa
    14221 aaaagaaatt aaaaaattat atgatacagc tgaaagtgga aaaatactta gagaaggttt
    14281 aaagacagta attgttggga aaccaaatgt aggtaaatct tcacttctta actccatttt
    14341 aggagagaat agagcaatag ttactgatat accaggaact actagagatg ttatagaaga
    14401 gtttgtaaac ataaaaggta tacctttaaa aattgttgac acagcaggta taagagatac
    14461 tgatgatatc gttgaaaaaa taggtgttga aaggtctaaa gaatcattta ctagcgcaga
    14521 tttgatagta atggttttag atgcatctag aaagttatca gaagaagata tagagatatt
    14581 agaaaaactt aaggataaac aaacaatagt gttgttaaat aagaatgatt tgaaacaaga
    14641 aattgaggaa gaaaaaatac ttaaatatgt agaaaataat agtataataa aaatatcagc
    14701 tttacaacaa gaaggaatag aagaattaca agataaaata gagtctatgg tatataaagg
    14761 tagtatcaaa aataattcta gtttagtagt aacaaattca agacataaag atgcacttag
    14821 taaagcatat aaatctgcaa cagatgcttt aattgctttg gaacaaagca tgccatttga
    14881 ctttgtagaa gtcgatttaa aaaatatatg ggactatctt ggatatatta atggtgatac
    14941 agtaacagaa gatttactag ataatatatt ccataatttc tgtattggta agtaatgtac
    15001 aaaagtaaat ttgtttttat tatagatatt ttttaaaaat ttgtagtgtt tctcatgaaa
    15061 cattaatttt aaacagaaag gaattataaa tgataaagtt tgaagcagga aaatatgatg
    15121 ttatagtagt cggagcagga catgctggat gtgaagctgc tttggctact gcaagaatgg
    15181 gatataaaac tttgataata acaatgtctt tggattctat agcattaatg ccttgtaatc
    15241 catcgattgg ggggactggt aaaggtcaat tagttaaaga aatagatgcc ttaggtggtc
    15301 agatgggact aaatatagac aagacatata tacaaagtag gatgttaaat actgctaaag
    15361 gtccagcagt gcactctttg agagcacaag cagataaatt taaatatcat gaagaaatga
    15421 aaaagacatt agaagatgaa ccaaaccttg atatagctat ggatgaagtt gtagaaatac
    15481 ttcacgaagg aaatgttgta ataggggttg gaactaaact aggatgttca tttaaatcta
    15541 aagctgtaat attggccact ggagtttatc ttaactcaaa gatatatatg ggtgaagttg
    15601 cattttatga aggtcctaat gcactgggtt atgcaaaata tcttacagat agcttagttg
    15661 agcttggtct tagaatgaga agatttaaaa caggaactcc agcaagagtt catagagata
    15721 gtatagactt ctctgtaatg tctttacaag agggagatga aaaagtaact ccattctcat
    15781 ttatgaatga aaatatagaa aaagaacaag aaccttgtta cttaacaaga actacagaag
    15841 aaactcaaaa agttatacta gataatttaa aaagatctgc tatgtatagt ggagtaatag
    15901 aaagtactgg tccaagatat tgtccttcta tagaagataa agtagtgcga tttagtgata
    15961 aaacatcaca tcaactattt atagaaccag aagggttaaa cactaaagaa atgtatatac
    16021 aaggaatttc aactagctta ccttttgaag ttcaattaga tatgtacaaa actataaaag
    16081 gacttgaaaa ttgtaagata atgagacctg catatgctat tgaatatgat tgtgttgacc
    16141 caactcaact aaaaataagt ttggaaataa agggcgttga gaacttattt agtgcaggac
    16201 agttcaatgg gacttctgga tatgaggaag cagcagctca aggacttatg gcgggtataa
    16261 atgcagttag aaaaatagaa ggaaaagagc catttgtatt agaccgttca gaagcttata
    16321 taggtgtctt attagatgac cttgttacta aaggaactaa cgaaccttat agaatgatga
    16381 catcaagagc agaatatcga ctatatttaa gacaagataa tgcagatatg agattaactc
    16441 aaaaaggtta tgatatagga ttagttaaaa aagatagata tgaaagattt ctaaataaaa
    16501 aggctgctgt agagaaagaa tttgaaagat taaaaaatga aagagttaca ccgaaagaag
    16561 taaatagttt gctagaagaa aagggagcaa caccaataaa ggttggaata tctctatatg
    16621 aatttttaaa gagaccagag gttacttacg aattgcttga agaattagga aaaggcgctg
    16681 gagaagatgt ttcaagagaa gttaaagaac agtgtgtaat aataactaaa tatgaaggtt
    16741 atatagagaa acaattgaaa caaatagacc aatttaaaaa acttgagaat aaaaagctgg
    16801 atgagaaaat aaattattca tctatagaag gtcttagatt agaggctaga cagaaattgg
    16861 atgatataaa acctatttca ataggtcaag catctcgtat atctggtgtt tccccagctg
    16921 atatatcagt tttacttata tacctagaac aagtcagaag aactagaggt ggcaaaggtg
    16981 aataatatgg aacttctgaa aaatgggatt gaaggtttta atatagatac gaatgatagt
    17041 atgttagaaa aatttaaaat ctatagagag atattaattg actggaataa aaagatgaat
    17101 cttactggaa tagaggatga aaaagaagta tatataaaac attttttaga ctctatttca
    17161 gctgtaaaga atggatatat aaaaaatggt atgtctataa tagatgttgg tacaggtgct
    17221 gggtttcctg gaataccatt gaaaatatgt ttagatagat tagaacttac tttgttagat
    17281 tcgttaaata aaagaataaa ctttttagag gaagttagta gagtattaga gttagataat
    17341 attaaattta tacatggaag agcagaagat tttggtaaaa atgaaaacta tagagaaaaa
    17401 tatgatgttg ctacagcaag agctgttgct ggattaccaa ttcttatgga attttgtgta
    17461 ccctttgtaa aagttggagg atattttatt tgcttaaaag gtccaaatgc taatttagag
    17521 ttagaagaat ctcaaaaggc tattgatgtt ttaggcttag agtatattga aaaaatagat
    17581 gtagaactac cagaaataga tttaaatcat aatatattag tttttaaaaa agtaatggaa
    17641 acaccagtta agtaccctag aaaggctggt aaaccagcta aaaatcctat taagtaatga
    17701 aaaaattatt agcggtaagc ttaattattt ctcaggaaat aattaagctt atcgtaaaaa
    17761 aacaaaaata aaggaattat taaagtagat gcagaaataa atttgtatgt acatatagag
    17821 aacaaaaata atttatatct aaaataagag aggtatgtta tggaagataa aagagttatg
    17881 gagataccta tagaagatgt agttccaaat ccatatcaac caagaaaaat attttcacaa
    17941 gtttcattgg aggaattgag taattctata aaggtatatg gtataattca acctataaca
    18001 gttagagcaa aagatggcaa atatgaacta attgcaggag aaagaagatt aagagcagct
    18061 aaattagcag aacttaaaac cataccagca attataaata atatgaatga tgaatcttct
    18121 gctgttctag cgttattaga aaatttgcaa cgagaagact taaatttcat tgaagaagca
    18181 attggttatg aaaacttaat aaaagaacat gcttttactc aacagcaatt agcagaaaaa
    18241 ttgggcaaaa atcaatctac tgtagcaaat aagcttagaa tattaaagct tccaaacgat
    18301 ataaaaatga agctaataga gaataattta acagaaagac atgctagagc atttcttaaa
    18361 ctaccaagtg aagatttaat gcaaagtgtg ttagacaaag tcataaaaaa tgaattgact
    18421 gttaaaaaaa cagaaaaatt gatacaagat gtattagaag aaactaaaat tcaagaagag
    18481 cctgataaaa aacagaatat aaagggtgct atgagtataa gaatttacat aaatactata
    18541 aagcaggcct ttgatgctat atcaaataca ggaattgatg ctaagtataa tgaaatagat
    18601 aagggagatt atatggaggt tgttgtaaaa atccctaaaa aatagagatt actgcttacc
    18661 agtaatcttt ttttgtaata taagccttgt aatataaatt gatttataga cattatttat
    18721 acttaaaaaa cacctattca acatttaaaa ttaatttaat tcttaaaggg gggaacatca
    18781 tgggcaaagt tatagctgta ttcaatcaaa agggtggagt tgggaaaact acaacaaatg
    18841 taaatttaag tgctagttta ggaactttag gaaagaaaat attagtatta gatttagacc
    18901 cacaaggaaa tacaactagt ggatatggta ttaataaaaa tgaagtagaa aatacaatct
    18961 atgaaattat gttagatggg ttacatatta aagaagcaat aataagtact gaatttgaga
    19021 atgtagatgt agttccatca gctactgaac tatcaggtgc agagatagag cttacatcta
    19081 aaactaatag agagtatatt ttaaaaaatt ccataaaagc agtaatagat gaatatgatt
    19141 atatattttt agattgtcca ccctcactag ggatgcttac aataaattgt ttaactgctg
    19201 tagatagtgt tttaattcca atacaatgtg aatattatgc tttagaaggt gttagtcaat
    19261 taatggagac tataaaatta gtaaaatcaa gactaaatgc tgatatagaa attcaaggtg
    19321 ttgttttaag tatgtttgat ggaagagcta acttatcaat acaagtagtc gaagaagtca
    19381 agaaatactt taaagggagt gtatatacaa ctctaattcc aagaaatgta agacttgcag
    19441 aagctccaag tcatggaaaa cctgtaattt actatgataa aagatgtaga gggtctgtag
    19501 cttatttgga actagcagaa gaatttatag atttagaaga ggaggaatgg tagtatggag
    19561 aataagtcta aaagaagtaa tagattgggt agaggtctta gtgcattgat accagaaatt
    19621 aaaggagaaa ctccagaaaa agaaatagtc aacatagata tagacaaaat atatccaaac
    19681 gaagttcaac ctagaaagca atttgatgaa gaaaagataa aagtattggc tgactctata
    19741 aaaaattatg gtgtattaca gccaatagta gttaaaatgg atgaaaataa taaatacatg
    19801 ataatagctg gagaaagaag atttagagca tcaaaacttg caaataaaaa tcaaatacct
    19861 gctataatta aagatataga tatgaaagat ataatggaga tagctttaat tgaaaactta
    19921 cagagggaag atttaaattc aatagaagag gctctagcat ataagagttt aatagaacat
    19981 tacaatgtaa ctcaggaaga gatatcagaa gctgttggta agagtagacc tcatataact
    20041 aacacactaa gacttttaaa tcttggacaa gatgttatag aaatgataga cagtggtaga
    20101 attacagcag gtcatggtaa ggctttattg agaattgcag ataaagattt gcaacttcaa
    20161 atagcaaaaa aaatagaaga agaagaactt tctgtaagag aagttgaaaa tatagctaaa
    20221 aaaatatctg aaaataaaca agaagaaccg aaaaaatcta aacctaagga tgtatttatc
    20281 ttagatgttg aagataaact tagaaatata tttggaacaa aggtgaatat ctctaaagga
    20341 aagaaaaaag gtaaaataga gatagaatac tataatgatg atgatttaaa tagtattgta
    20401 tcaatgcttc ttgaatagaa caaaaatata aaacagagag gaagattgtt atgatttatt
    20461 tagataatgc tgcaactaca tatccaaaac cagaaagagt gtataatgct gttttagatt
    20521 gtatgaaaaa ctattgtgca aacccaggta gagcaggtca taaacttgct atgagagctg
    20581 ctagggagat atatgacaca agagagaata tagctaagtt gttcaatgta agtaatccta
    20641 tgaatatagt atttacatct aatgcaacag attctttaaa tttagcaata aaaggcgtat
    20701 tacaagaagg agaccatgta ataacaacat ctatggaaca taattcagta ataagaccta
    20761 taaaatcatt ggaaaaaaaa ggtattgaaa atactgtagt aaaatgcgac tatgaggggt
    20821 ttctaaatta tgaggattta gaaaaagcga taaagagtaa tactaaattg attgtaacaa
    20881 cacatgcatc taacgtatgt ggaactttaa tagatataaa aaaagttgga gaaatagcta
    20941 aaaaacataa tatactattt ttagtggatg catcacaaac agcaggtgtt tataatatag
    21001 atgtaaatga atgtaatata gatatgttgg caatgccagg tcataaatgc ttatttgggc
    21061 ctcaaggaac aggtatatta tatgtaagag aagggttaaa cttaaatata ttaaaagaag
    21121 gtggaacagg tagtaaatca gaagaaatag ttcaaccaga gttattccca gataaatatg
    21181 aatcaggaac tcataatact ccaggcatag caggtcttaa ccaaggtata ttatttatat
    21241 ttgaaagagg aatcaacaat ataagacaac atgaagaaga attatgtcaa tatatgatag
    21301 acaaattaga ggaagtccca gatataaaga tatatggacc aaaagatagt aaaaaaagag
    21361 cagcagtaat agctctaaat ataggaaata tggattctgg agaggttact ttcttattag
    21421 acagtgatta taatatagca accagatcag ggatacattg ctctccacta gcacatacca
    21481 ctttagggac tttaaaacaa ggagcagtaa ggtttagtat aggatatttc aacacaaaag
    21541 atgagataga taaagcagtg gaagctttga aaaaaatttc taaaaataaa tagcatgaaa
    21601 tttaagaata tataaaaata aagaaaggag atgtttcaaa ataaaaattt gaatcatctc
    21661 cttttttgta caaaaaagaa aaggggttcc taagaatccc taatctattt gataattgtt
    21721 tcaagaaatt attttaagta atctccttct tcaagaacta tatgaccact ttcataatta
    21781 gaaccatcaa cagtgatttt tatttgttca acattcatat tttttatgta agtacgagca
    21841 actgaatcaa gcattaaagc ttctgcatca ctacctaaat ttgactttgt aaaatcggag
    21901 ctaacatcta atataccagt ttttacacca tcaatgtctt ttgtagtaaa tgaatttaat
    21961 tttgcagatt ctggaacaac tttaagtttt tgaagttctt caaataaagt gttttcatca
    22021 attttactta aatcaacctt gttttcaatt aaatctgtct tatctacatc aaaagagtaa
    22081 atagtagctg attgagtttt agtttcttct tttggagtag gtttagtttt gttattagga
    22141 acctcttttt cagtactatt ttcttctttt ggttgttcaa catttgtatt actcttagtt
    22201 tcttttttag atgtatcatt tccattttga gcattagtac aaccaactgc gaatatagat
    22261 atagataata tacttaacac taacattatt ttcttatttt tcataaaaat ttctcccttc
    22321 ttaaaaacta ttcttatata taattatagt cgttatgagc aaatatatga atacaaaata
    22381 gtaacaaatt taaaaaatga tttatttaaa ttaattaaat tcaaaataaa ctaaatttta
    22441 gtcattttta tgggaaatca tttaatgtac actgaaaata ttgtaaaata aaagtagtgt
    22501 ttttaaaata aatataagtt ataattatat tataaaaaaa tgtcttcaaa aggtgggaat
    22561 agtatggaaa ttttgagctt aggagaaaag attaaaaaat taagaaaaga aaaaaacatg
    22621 acattaaaag aattagctgg agataggata acagcagcac aaataagcca tatagagagg
    22681 gataaatctc atactagtta tgaactgttg gaatatctag gcgataagct agatgtaagt
    22741 gtagaatatt tattagagac caaggaaatg caatcaaaaa agataactga taatttaata
    22801 ctacagagcg aaatttatat aaaagaaaat gagttaaaca aggctgagga ccaaataaaa
    22861 gaagttttag atatatgtaa gagatacgat ttaatggaga actatggcag atgcaatttt
    22921 ttaatggcta atattaatct gaaaaaatct aattataatg atgctataga aaactttgaa
    22981 aaggcattgt acttctttat aaaaaatagt gatagtgaaa atatacttaa gtgttattta
    23041 aacataggga aaatatatat gcaggaagac ttttataaag gtgctataag ccactttaat
    23101 tttgcagagg aaattttgtc agagaataaa tttgaggatg ttaacataca caaggaacta
    23161 tatagtaaga tggcatattg ttacataaaa ctagataatc caaatatgtc attgaaatac
    23221 atagaaaaaa taaatgaaat agataataga aatgatagaa aagaagatgt cgatattttg
    23281 gtattaaaag caaataatat gcttgaaatt gggaaatatg aggaatcaag agattacttt
    23341 aaaaaagcgc taaaaatact tgaaagtgaa gataataaaa ctggattagc aaatgtgtat
    23401 ttaacaattt gtgacgttta cagaaaaata ggtgaaacag atagagtact tgaatattca
    23461 caaaaggtat atgacataaa gaaaaatgat gaagatgaat atatgatgtc aggattattt
    23521 aagataatag aagcatatat agataaagaa gattatgatt tagctagaaa atattgtaag
    23581 atagccttag cttcatcaat aaaaaataaa aataaattca atgaatataa agcattgaga
    23641 ttctatgcta atatgtataa aaatcaaaat gaaataactc ttgcaattga atatttgatt
    23701 aaatgcataa aaatagtatc agatttagga aacaatagaa tattggccaa tttatatata
    23761 gacttaggtc aattatattc aaatatatca aaagaaaaag agttagaata ttatcaaaaa
    23821 ggtgtattta tgtacaaaaa cttagaaata atgtagagta aataaaccta taagggtata
    23881 gaaacaatct ataacaagca agataatatc tatgataaaa tataaattgt atgaatattt
    23941 ttaaggagat gaatcagaca atgagtataa aaatagatgc aagagggctt gcttgtccta
    24001 aaccagttat aaatacaaaa agagaattgg ataaactaga agaaggtgtt gtagttacaa
    24061 tagttgacaa tgaaacagct aaggagaatg tattaaaact tgccaaatct ttaagttgtg
    24121 aagcaaatat tgttgatgaa aaagagaatt ttatatctat agaaattaga aaaggtaaga
    24181 atatactaga taaacaaaat attgtagata ataaagaaag tgaattagac aatacatgta
    24241 tatttatatc ttcagataag atgggacttg ggaatgacga attaggaaaa gtgttaataa
    24301 aaggatttat atatacatta acagaatcta aaccttatcc taagtatgta cttttagtta
    24361 atggaggagt aaaattaagt gctgaaaatg aagaaactat agaaaatcta aaaatacttg
    24421 agaatatggg tgtagaagtt ttatcttgtg gtacttgctt agattattat aatttaaaag
    24481 ataaattaca agtaggtaca gttacaaata tgtatactat agttgagaca ttaaagaatg
    24541 catcaaatac tatttctata taatgtattt ttgtttagta atataaaact aataataaag
    24601 attaactcaa atagatagtc agaaaggatt aagtaatgaa tcaaatgtat atagtgtcat
    24661 ttaattcgac acatcatgcg ataagatcag aaaagttatt tggtgaaaat agtctaaaag
    24721 taatggctct tccaacacca agagaaataa cagcaagttg tggaatatca attaaatttt
    24781 cttttgaaga tatggaaaag ataaaaacta ttttaattga aaataatgta gatataaaag
    24841 gaatttattg tataagtaaa ttagaaaatg gttcaaaaga agtagagaag ttagattagg
    24901 aggctaatta tttatgccaa tggatttaaa aataggtgat attgttgaat taaaaaagca
    24961 acatgcatgt gggtgtaaag agtttgaaat cataagaaca ggaatggata taaagataaa
    25021 atgtactaaa tgttcaaggc taataatgct tgatagagag accttagaaa agagagtaaa
    25081 aaagctaata aaaaagtgat aaaaatttaa cacttaaaaa atgtcaaata ccgtatatta
    25141 atatccaaaa ttttggtata ataagaattg aagaaaacat tttcatgggg gtgctttaat
    25201 tatggcagtt aaatatgcaa aaagaatgca aggtttacaa ggatcagaaa tacgtgagct
    25261 tttaaaactt actcaacaac cacaaataat atcttttgct ggtggaatgc cggctccaga
    25321 gttatttcca gttgaggaaa tgaaaaaagt atcagttgca gtgcttgaag aaaatggaag
    25381 atcagctatg caatatacta caacagaagg atatgaacca ttaagagaaa aaatagcagc
    25441 tagaatgaat gataaaaaca aaactaatgt aaacaaagat gatatattag ttacaagtgg
    25501 ttctcaacaa ggtctagatt ttgcaggaaa agtatttatt gatgagggtg atgtaatttt
    25561 atgtgaaagc ccatcttaca taggagctat aaacgcattt aaatcttacc aacctaaatt
    25621 catagatgtt ccaacagatg ctgatggaat gataatggaa gaattagaaa aaatactaga
    25681 aacaactgat agaataaaaa tgatttacgt aatacctgac ttccaaaatc caacaggaag
    25741 aacttggcca cttgaaagac gtaaaaaatt catggaaata gtaaacaaat ttgaaatacc
    25801 agtaatagaa gataatccat acggagattt aagatttgaa ggagagactt taccatcttt
    25861 aaaatcaatg gatacaaaag gattagtaat attcttagga actttctcta aaatattctg
    25921 tccaggatac agattaggat ggacttgtgc ttctccagaa attttatcta aatttaactt
    25981 tgcaaaacaa ggtgcagact tacaagcatc aactatatct caaatggaag taagcaaatt
    26041 tatggatatg tatgacttag atgcacatgt tgacaaaata aaagcagttt atgttaaacg
    26101 tagagatgta atgcttaaga ctatggaaga agaattccca gaaggattag tatttactca
    26161 tccagaaggt ggattgttta catgggtaga gcttccaagt aatttaaatg ctaaagaatt
    26221 aatgccaaaa tgcttagata agaatgttgc ttatgttgct ggaggaggat tcttccctaa
    26281 tggtggtaga gaaaatactt tcagacttaa ctattcaaat atgccagaag aaaaaataat
    26341 agaaggtata aaaaatatag cagctgtatt aaaagaagct atgggtgtag aagcttaatt
    26401 aaaaataata acttatatat aatacaaggg atggttattg ccatcccttg tttgtttgaa
    26461 aaatatataa tctaccttac actaaacttt gtccaaaatt taaattgaca gaaataagaa
    26521 taaatgataa aatgtgtagg tatgagattt tagtctcatt tctctgctct aagagtgtag
    26581 agccgttaag tccaaaggga ggtgaattat agtgagaaat tatgaattag tttatgtggt
    26641 aaagccaaac tctgatgaag aagtaagaga ggctatacta aacaaagtta aggaagttgt
    26701 tgcaactgac ggagaaatag ttaaagttga tacttgggga actaaaaaat tagcttatcc
    26761 aatagctaag tttacagaag gtttctatgt attagttaac ttcaaatcag cagtagacgt
    26821 tcctaaagag atagacagaa acttaaagat aaatgaaaac gtaataagac acatgatagt
    26881 tgttgcttaa taactggttt tattataaaa aataggtggt gtttttatga atcaagttgt
    26941 attagtggga agattgacta gagaccctga attaagatac atcccaggta caggaacacc
    27001 agtggcatcc tttacaatag ccattgatag agactatgta aaaaaagatg gatctaaaga
    27061 aactgatttt atacctgttg aagtaatggg taaatctgcc gaattttgtg ctaactacat
    27121 aactaaaggt agattagtag cacttcaagg atctataaga gtagacaatt atcagacaca
    27181 atcaggtgaa aagagaactt ttacaaaagt aagtactaga tcagtacaag ctttggatag
    27241 taagaataaa tcggaaaatt catatagaga gagtgctcca gcttttgagc caagctttga
    27301 acctcaaggt ttagacccac aaggtttcca agctatagat gatgacgata taccatttta
    27361 aaaaggaggg aaaaaagtca tgatgaataa aaaaagacgt aagaaaaaaa gagtttgtca
    27421 attttgtgct gacaaaaacg ctaaaataga ttacaaaagt actcaaagat tacaaaagta
    27481 tataactgaa agaggaaaga tattaccaag aagaatatct ggaacttgtg ctaagcatca
    27541 aagagaatta acagttgcta taaaaagagc gagaaatata gcacttttac catatacatt
    27601 agactaaaaa aatgagcctt gtgctcattt tttattatat ggatttatat atctaaatga
    27661 ggcgagctat aaagctcgtt tttttgttta tatacttaaa tatattatta tttatgatat
    27721 aatattatat attaaggagg gttgtaaacg tgaaaataga taaaggttct gagataacaa
    27781 gaaacataaa gataatagaa tggatgaaaa cagaaatatt aatgagtgta agtgatttgt
    27841 ttaatttatt gtttaaaggg gtaaaaccat tagatgaagc aattcaagat actttagcaa
    27901 atataataat gataacatat ctcttagcca agagattagg aatcagtttt agagatgtgg
    27961 attataaagt caaggaaaaa ataaaaattg gtatagatga ggaccatagt gttgaaagat
    28021 ggtatggaga tttatctaat ttaaaaaaac atatggataa tagggagtga tattaaattg
    28081 aataataaaa ttagactatc taaggcaatg tctataataa ttttagctat aataatcgct
    28141 ttagtaatag cctatattcc aatgctagga atatttagta tgttagcagc tgttccatat
    28201 gtaattatag gtgctattac tgatagaaag tattctctta tatctatttt ggttacattt
    28261 tgtgtactga ttctcttttc agacatttct tatgcattaa atatatgtat aatgtattct
    28321 ttaccaggtg tagtaatagg aaagatgcta aagagaagtt ttgaacaaga ggacagtaat
    28381 aaattcgaac cgatatatgg tggaaccata atatttgtac tttcaatgct tgtatatttt
    28441 tttgtattaa agacattttt aaatgtgaat ctattagatg aagtttctaa gatgatatca
    28501 gaaattgtaa atattcaaaa aaatactttt tctgcaaccg agcttaaagt gtttgataaa
    28561 atgaagccag atgagattgt aagttatttt acaaatatgc taccaatgat gttattttta
    28621 caagggttgc tatcagcgtt tgtcacatat tatttgagtg tattttttat aaaaaggatt
    28681 acaaagatga atataagatt tcctaaattt gctgattttt atttaccggg aaatgctata
    28741 ctcacaactt tcttacttta tttattggtc ttatttattc aaattattgg ttcaagacta
    28801 tacacagaat tgataatgac taatttacag ctagttttta atttaatgtt tgtaattcaa
    28861 ggtatagcag tttgcattta ttttttaaag aaatggataa gacagggacc aaataaaatt
    28921 atgttttttt cagggataat tttatgttta tttggattta tgggaatatc ttttgttggt
    28981 atggtagata gtataattga ctttagaaag gtaagaagct ataaatccac ttaggaggat
    29041 agaaatgagt aataaacaaa cctttaaatt aaatatgcca gaaataaatt tatatataat
    29101 tgttattggt atttctagta taattttgct ttattacaac ttgtatgtag ggtgtttatt
    29161 tttctgtatt tttgtatata tggttttcca taattggaga acaactaata tcagacatca
    29221 tgaatggaca gagtatattc aaaatttatc tttagatata gatgaaacaa ctaaaaaagc
    29281 cataataaat cttccaatac cattatgtat tttagaattt gatggaaata tatcctggta
    29341 taatggaaag ttttatgata tgattggtca aaaagattta ctagataaaa atatagaaga
    29401 tatagttaaa aatcttaatt taagaaaagt attaaatgaa aataaagaga tgtacacaga
    29461 aataaactat aaagaaaaag aatatacaat aatttataat gttataaaaa atgatcaaga
    29521 aaaaaatcct aaatatttga tgatattata ctggatagat aagactgaat atttaaaagt
    29581 aaaacaaaat tatgatgatg aaaaaaatgc aatgatgcta atacaagtag atggatatga
    29641 tgaagtatta aaaagtgcag cagaagataa gagagcttta attaacgttg aagtagagaa
    29701 aatactttct gctttagaat taaattcaaa tggtgcattg agaagaacct caaaagacaa
    29761 attcttcttg gtaatgcata aaaaagagtt aaaaaaattg gaagctgaga agttttctat
    29821 tttagataca ataagacata ttgattatgg aaataatctt cctgttacta taagtatagg
    29881 aattggtata gatggagata cattaaatga gaacctaaaa cttgctacag gtgctctcga
    29941 tttagcactt ggtagaggtg gtgaccaggc tgttgtaaaa acaaaagata aatttgtgtt
    30001 ttatggagga aaatctaaag ctgtagaaaa gaagaccaag gtaaaatcta gattaatagg
    30061 tcatgcttta agagaggtta tacaacaaag tgaccaagtt tatataatgg gacataaata
    30121 tcctgatatg gatgctatgg gagcagcagt tggtgtttat gatatatgta aatcatgtaa
    30181 caaaactgca aacatagttt tacaatctgt aaatgaatct atagaaatat ttataaataa
    30241 aataaatgaa aataattact ataaaaaatt gtttattggg aaagaggagg ctattgacaa
    30301 ctgtactaaa aatacattag ttgtagtagt tgatactcat agacctaatt atactgaatg
    30361 tgaagagcta ttaaagctat cagaaaaggt agtagttata gaccatcata gaagaggtgt
    30421 ggagtttata aatgatgcag tgcttttatt ccatgagata tatgtatcct caacgtgtga
    30481 aatggttaca gagttagttc agtatatgga tgaagatgta acaataaata aacttacagc
    30541 tgaaggactt ttagcaggta taagtctgga tactaaaaac tttgcattca aaacaggtgt
    30601 taggactttt gaagctgctt cttaccttag aaaagttgga gcagatacta tagaggtcaa
    30661 gaagttcttc aactctgatg taaaagactt cataataaaa gctgaaataa ttcaaagtac
    30721 taaaataatt aataatagaa tatgtttagc atattcaagt actgagatag atagtataaa
    30781 tgttataata gctcaaactg ctgatgagtt actaaacatc aaagaagtag aagcttcctt
    30841 tgtattaggt gaaaaagatg atactatatt tataagtgcg aggtctttag gacaaataaa
    30901 tgtacatgtg cttatggaaa aattaggagg cgggggacat atagacatag ctggagcaca
    30961 gttaaaaaat gtttctctaa aagaagctta taagatggta aataaaataa tagaggagta
    31021 tttggaggag gaagaataga tgaaagttat attattaaaa gatgtaaagg gaactggtaa
    31081 gaagggagaa atgaaagaag taagtgatgg atatgcaaga aatttcttat ttcctaaaaa
    31141 gatggctgtg caagcagata gtgtagcaat aaaagaatta aatgaaaaga ataaatctaa
    31201 agaaataaaa gcacaaaaag agtatgaaga agcagtttta ctaggtaagc aaatggaaga
    31261 aattaatata gaaatatatt caaaagcagg agaaggtgga agattatttg gttcaataac
    31321 ttctaaagaa attgctgaac aattaaagaa acaaaaagat atagatgtag ataaaagaaa
    31381 aatattatta gatgaaccaa taagagcttt aggttcaact tttgtagaaa taaaaataca
    31441 tcaaaaggta actactaaaa taagagtgga tgtaaaagaa aaacagtaat aattagaggt
    31501 gattaagatg gaagatatga cgagaattcc tcctcatagt gtagaatcag aacaatcaat
    31561 attgggttct atacttttag ataaagatgc tataataacg gttacagaaa ctataaagcc
    31621 tgatgatttc tataaagaag ctcacaaaat aatatatgaa tgtatgataa ctttaagtaa
    31681 taaaggtgag cctatagact tgataacatt aacagaagaa ctaagaaaac aagggcatct
    31741 taatgatatt ggaggaatca gttatattac aagtctttct actatagtac cgacgacttc
    31801 aaatgtaaaa tactatgctg acatagtaaa agaaaagtct gtacttagaa agcttataaa
    31861 agcttctaat gaaataataa atctaggata tagtggagca actaagattg aagatgtttt
    31921 agaacaagct gaaaagagta tatttgatat atcacaggag aaaactagtg acgattttaa
    31981 atctataaac ttagttttga tggatgccta tgatatgata gaaaaattat atactaacaa
    32041 gagcgatgtc actggtataa ctactggttt taaagattta aacaaaaaaa taaatggtct
    32101 acaaaggact gatttaatat taattgcagc tagaccagca atgggtaaaa ctgcattttc
    32161 tttaaacttg gttcaaaatg cagccttaaa aggtgatgct tctgtagctg tatttagttt
    32221 agagatgtct aaggaacaat tggtacaacg tatgttatct tcacagtcta gtgtagaatt
    32281 aaaaaaaata aagactggaa cacttaatga taatgattgg cctagaatta tagatgctat
    32341 ggcagtgtta tcagatgcca aaatacacat agatgatact cctggtataa aaatatcaga
    32401 actaaggtca aagtgtagaa aattaaaaat agaaaaagga ctagacttag tgcttattga
    32461 ttatcttcaa cttatggaag gtgaaggtaa taatgaaagt agacaacaag agatatctaa
    32521 gatatcaaga tcactaaaaa tattagccaa agaattaaac tgtcctgtag tagcactatc
    32581 ccagttatca cgtgcaccag aacaaagagc agaccataga cctatgttat ctgatttaag
    32641 agagtctgga gcaatagaac aggatgcaga tatagttatg ttcttatata gagacgaata
    32701 ttatcatgct gattctgaga gtaagaatat aggagaagta ataatagcaa aaaatagaca
    32761 tggtgaaact ggttctgtgg aacttgtttg gcttggtgaa gttcaaaggt ttggggataa
    32821 gttgagagac ctataatata acgaatatcc acagaacgtc ctttctttct acaggaaaaa
    32881 tgtggataca tgtcactaaa tatgtctaaa cattgaaatt tagctaaaaa attatccaca
    32941 gtatccacag atagcctgtt gataagtgtg aataagtaga taaagcaagc ttttggcttg
    33001 ctttatctgt gtataaatat taattattag gaggaataat atggaaaaaa taagcttaaa
    33061 atatatatat cccaatataa ttaaagtact tgatgaaata aacttattta gagtaattga
    33121 taataattta agagaatcta ttgttgttta tgctaataat gtggataatc agtatcatat
    33181 aaacatgact aatacaaact ttggaaacat aattaacata tgtaaattag aaaaactttt
    33241 agatgtggat aagtttatgg aaaaagttat aaaatcagaa aaagaaataa tagagaaaga
    33301 agagttttca aaaatagaag aatatatgtt aaatattgga gaatactaaa aaagttgaaa
    33361 aaaatacgaa tgtttgatag aataagtaag tagagtgttc gagagtatat aaaatataga
    33421 ggtgaattac atgaaaacag ttgcaattgt tggttctcaa tggggagatg aaggtaaagg
    33481 taaagttata gattatcttg ctactcaagc agatgtagta gtaagaggac aaggtggaaa
    33541 taatgcagga catacattag ttgtggaagg taaaaaatac gcattacatc taattccatc
    33601 tggagtttta aatccaaata cagtgaatat aatcggaaat ggaatagtgt ttgaccctaa
    33661 aggattttta gaagaattgg aaatgtttaa aatggataat ataagtacag aaaatataaa
    33721 aataagtaat agagcacatg tcatattccc atatcataaa gaactagatg tattgtcaga
    33781 agaagccaga ggcgatttaa agataggtac aacaaaaaaa ggtattggac cttgttatat
    33841 ggataaaaca gagagatctg gtattagaat atgtgactta atggataaag ataaattcgc
    33901 tataaaatta aaagctcaaa tagatgctaa aaatgaaata gttaaaaata tatatggaaa
    33961 agaagaatta tttgattttg aaactatata taatgaatat ttaggatacg cggaacaaat
    34021 aagaaaatat gtggcagata catcagttat tgtatatgat gcaataagag caggtaaaaa
    34081 agtattgttt gaaggagcgc aagggacttt attagattta gatttaggaa cttatccatt
    34141 tgttacatct tctcatccaa catctggtgg atttgcaatt ggtgcaggta taggaccaaa
    34201 tatgataaaa gatgttgttg gtatagtaaa agcatatact acaagagttg gagaaggacc
    34261 atttgttaca gagcaaataa atgaaactgg agataaaata agagaacaag gtcatgaatt
    34321 tggggtaact actggtagac caagaagatg tggatggttt gatgcagtta tagttaagta
    34381 tgcagctaga gttaatggat tgactagtat ttcatttatg ctacttgatg tattaactgg
    34441 atttgataag ataaaagtct gtacatctta caaaatggga gataagataa taacagattt
    34501 cccagcttca ttagatgatt tagcaaaatg tgaacctgta tatgaagaat tagatggatg
    34561 gaatgaagat ataactcaaa tagataactt tgatgacctt ccagaaaatg caaagaaata
    34621 tgtagccaaa atagaagaac tagttggagt aagtgtagat atggtttctg ttggtccaaa
    34681 tagagctcaa accataataa gaagaaatat atttgcttaa tattttatca attagataat
    34741 ttaaattgta aatagttgaa gaagagcatc ttaagataat gtttataatt attagagatg
    34801 ctcttttatg ttcgacttaa atttattttt tattaagtta aaattactga cacacattct
    34861 aactgaaatt aaagttgaat ttgtgtagag atgtataggt ttttaaaaag aattttgttg
    34921 aaaataaata gctaaagatg attttaatta tatgctaaaa aaaataaaaa aaactattga
    34981 ctaaaaattg tatagaagct ataatataac ttgtgagtga aagaaacgac gaaaaaagtc
    35041 gaaaaaatgt ggtctattag ctcagtcggt agagcacctg acttttaatc agggtgtccc
    35101 gcgttcgagt cgcggataga tcaccaaaat atggctcgtt ggtcaagagg ttaagacacc
    35161 gccctttcac ggcggtaaca ggggttcaat tcccctacga gtcaccagta tgggactata
    35221 gctcagctgg gagagcacct gccttacaag cagggggtca caggttcgag ccctgttagt
    35281 cccaccatat ttttaattag agataaaaac tagattatat gctggtgtgg ctcaacggta
    35341 gagcagctga cttgtaatca gcaggttgta ggttcgattc ctatcaccag ctccacaaag
    35401 tacataaatt taaattaata taattttcta tgttacagga tacttttaag tatctttttt
    35461 taatttcatt ttttattgta ttaaaaatga aatttacata taacaaaata ttgaattact
    35521 tgtaatgtga tagttttgaa tctaaaattt agaaacattc tagaatagta ttatgtaatt
    35581 agcaaattta atttatagta ccaataaata tagattgcta agaatataaa tgatttgtta
    35641 ggttaagata cattagatat gtaaatagaa aaataaaaag tatggtttaa tttatgtggt
    35701 ataagtttta aacagagaag caagtttgct cttacctctc tatttaaaaa taaaaaaatg
    35761 ttttttaagg gctattttat ttgaatcttt cccatctcaa atcatctcca gtaaattcta
    35821 aaatcctaaa cttatccaag attctagaga gagttctttg agtataagta tttcctatct
    35881 gagatggtgt taagttggtt gaaataatga tttttttacc agcaacaagt cttgtattta
    35941 caatattaaa gatttctcca ctagtaaaag aattattaag ttcagtacca aggtcatcta
    36001 ttattaataa atcgcaatca aacaagtttt tataattatc ttcacttatc tgattatttg
    36061 agtctctcct aaatttataa tcttcaagaa tatctaagat tctaaaagaa gtttgataga
    36121 ttacaacatt gcctttatct aacaattcct ttgcaataca attgcacata tatgtttttc
    36181 ctagtccagt agaaccataa aacagtaaat tttcactatt atctttctta aaatcatgaa
    36241 caaaattttc gcagatactt aaattgttta gcatattttc tctaggagat atttccccat
    36301 cagaactttt cttaggagaa aatatattca agttaaaatt cgaaaaattt tcctgactta
    36361 aaatcctatc taaattagac attttataag cttcatttac aatttcttgt ttaaggcaag
    36421 aacatttttc accattaggt aaaaatcctt tatctttaca agaaacacat tgaaacttta
    36481 tttccaaata atcaagaggt atgttatttt cagttaaaag tttttctttt tttaatttta
    36541 aagactctat attctcttta gtcttcttta caatttcatc tttagattta ggatttaaaa
    36601 gtactatttt agctaatctg agacctattt tagaaatttc atcatctaaa gattttattt
    36661 cagggattct attatatacc tcattttttc tatgttctaa taagagttca ttatcatctc
    36721 ttctcttagc atatttagca agtatttttc ttattttatc ctcattcatt taatcaccta
    36781 cttaaacttt tctttttgac tttttttaat aatctcatcg agctcatcag atgtatattg
    36841 agtgaatgtt tcgttgaaat tatgaaactt agttttcttg taagtattgt tgttttgagt
    36901 agtattaatc tgcttcttat taatattctc cttaactata cgttcttcct ctttttgctt
    36961 taaatcattt aaatttttta tatttttttc attccaattt ttaattatac catttatata
    37021 agatatactt gggtttgaaa tgttcttaga cttggaacat gcttttatta tcaaatctat
    37081 atccatatta aatttatcaa accaagtgtc cataagttct ttttctgact ttgatggttg
    37141 tcttgaaaat cccaattcat tgaaaatcgt tttatataaa atatatcttt cacttcttac
    37201 caaaaagctt tcttcaacat cttttggtgt atataaattt gaatcatacc aatttctaat
    37261 aataccttca atatatttaa ctggctttga tgtaccagtt ttatctttga cgtattcata
    37321 tgcgcaaagt atcatatcag ggctcatatt gtatttattc attatatcca taatactcat
    37381 cttttcactt gggtcgagat atcgcccaac tattttattt atagagttaa acatttttct
    37441 aatgcttgga ttttcagaag tagatacaac cttatctgta ttagatttta cagatgaatt
    37501 attgcttaat atattctcaa tatagaaatt ttttaaatct aaaaattcta ttgaataatt
    37561 aaaattatca tattctccat tgtcatgtat ttttataatc ttcttttcct cccagaattt
    37621 ccaagcagat aacacatcag acaatggtat atttaggttt ttggctattg aactattatc
    37681 gaacttagga ttagaagtaa tgtcgcatgc ctgtctatat cctaaaagat aaacttttac
    37741 gtataagccg tccgccattg gcataaatat atctataaag atattgggaa tagtgatttc
    37801 acctaaatct atttcattgc tttctttaaa aaacatttta tcacctcaga ttaaattata
    37861 tcatttttta tattatattt gtctgtaaac aaataaaagg tcacaagatt agcatgtaaa
    37921 tattttctaa aagtattcat tttgaaaagg aggagatatt ttggttataa aattcaacca
    37981 aaaagtaaga agaacattat cagtagcgat tctatttatg gtattaataa taggttgctt
    38041 tatagaaaag gatgacagtt tagaaacata caaagaaaaa actaattcaa aaataaatca
    38101 atataatatg gatgttatat ttgatgatga gactaagagg ttaatgtgca atcagaatat
    38161 tgagtacata aataatacaa aatcaaacat agataaaata tatttacata tatatccaaa
    38221 tgctttttcc aaaaaagatt ttgctccttt tgaaaaaagt gaaatgacaa gggcctatcc
    38281 taatggattt aacgaaggat atatagatat aaagaatata ttaaataaca atagtaaaat
    38341 ggagtataaa attaaagggg acaaaaatga catattagaa atagaattgg ggaaagagtt
    38401 aaaaccaaat gaaagaatgt cattagacat aaaatataac gtaaaaatac caaactcggt
    38461 tggaagattt ggatatggag aaaatactat aaatgttact aattggtttc ctatagtttg
    38521 tgtaaatgat gaaaggggat ggaatttaaa gagttatgaa actattggtg acccatttta
    38581 tagtgaaact agcgattttc atgtgaaact attgattcca aataaatata aaattgctca
    38641 tacaggaaaa cttgttaatg ataaacatga taataagaaa atgctatatg aaatagaagc
    38701 taaaaacgtt agagattttg catttatatt aagtagtaaa tttgatgtga ataaagtaga
    38761 ttcaaagggc gtagctatca atacatataa tttaaataaa aagctttcta aaaaagcaac
    38821 tgaagttgca aaagattcaa taaatatatt tagtgaatta tttgggaagt atccttacaa
    38881 agaattttct gttgtagcaa gtgacttttt tataggggga atggaatatc ctatgcttgt
    38941 tatgatagac caaagtttat ataatgaaaa aaatgaattt ttactagaat atgttattgc
    39001 tcatgagaca gcacatcaat ggtggtattc tgccgttgga aatgatgaaa taagtgaacc
    39061 ttggttagat gaagcactta ctgaatattc cacaatagtt tattttgaac aaaagtatgg
    39121 taaagatatg gcaaataagc ttataaaaac tatggagata cagacaaaaa gttatttgag
    39181 cgaaaatata tttaggccag cgaatgaata taaaaattct actgaataca gtttaaatgt
    39241 ttatacaaaa ggcgcaatag cgtttaatga aataagaaaa gaagttggag ataaagtatt
    39301 ctttgagact ttaaatgaat actataataa atataaacat aaaaatgcta atggaagagc
    39361 ttttgtggaa ctatggaata gtaaaggggt agatataaat aagattataa gtgaatgtaa
    39421 gtaaatttct tatagagtat taaattttat ttaatactct atttttttgg tataatataa
    39481 tttataaggc agaaaaagag gtgaaggaat gctaaagtat tgttcagtag ggagtggtag
    39541 tagtgggaat tgccactata taggatataa aaatactaat atactagtag atgcaggatt
    39601 aagtggcaag agaataacta caggtctcaa agacattggt atagatgcag ataaattaaa
    39661 aggaatattt ataacacatg agcatgttga tcatataaaa ggagcaggta tactatcaag
    39721 aaagtttgat ataccagtat ttgctaatat aaagacatgg tgttctatga aggacaaatt
    39781 aggtgatatc aaagataaaa atatgaaagt atttgaaaat gataaaacct attcattagg
    39841 tgatatcata gtgagacctt tttcaataga acatgatgcg tctgacccag ttggatataa
    39901 tttttataca gagaatgatg aaaaaatgtc tatagctact gatataggat gcataactca
    39961 aaatataaaa aaacatctat ataaatctaa gttagtagta ttggaatcaa attatgaccc
    40021 taacatgctt atgatgggtt catatacata tgctttgaag aaaagagtaa tgtcaaatgc
    40081 tggtcattta tcaaatgaag atgcagctaa tttctgtgtt gaacttatta atgaaggcac
    40141 agaatctata ttattagcac acttaagtaa agaaaataat tttcctgagt tagcatatga
    40201 gacctcaaaa ggagtattag catcaaatga tatagtagtt ggacaagatg taaaactaga
    40261 tgtactatca cgaaatgatg tttctaatgt ttatgagatg aagtagaggt gaataacttt
    40321 gctaaagaga aatttcgaaa acgttgaaga taataaaatt ttatactcta taaagcaggg
    40381 aatgatttta gcaatacctg ctattatgac tggttcaact gctcttgtaa ttttgaatct
    40441 tccaataaag gtttatcaag aatatttatc aagcttgttt aatggagagg ttacaaatat
    40501 tcttaacttt ataaatgatt ctactttagg aattatttca ttaataatat tattaacaat
    40561 aagctatagt tatgggaaaa tatatgggag caagtataca gtacttgttc ctatagttgc
    40621 aatgtgctct tttttagtat tttcacatgg taatgagctt gattcctata tagaaatatt
    40681 taagacaaag tggttattta catctataat tgtttctatg acatcttctg tattatttgt
    40741 aagacttaca gaatcttttg ttacaagtgt aaaatttcat acagaagggg ctgatgcaga
    40801 ctttaatatg gtagtttcag ctatagttcc tttcataata gtagtatttt tattctctat
    40861 ttttagagta ataatgataa gtctaattgg cagttcaaac tttcaagata tattttataa
    40921 tttattttca aatgtgttta atagaatggg aacaaatctt atgagtgctc tgttgtttat
    40981 ttttttaatg cactttatgt ggttttttgg gattcatgga ggtaatgtat tagatactgt
    41041 tgcaaaaaat ttatttgaaa atagcatggc aattaacata aatttagtta ataataatca
    41101 gttaccaaca gaaattttta ctaaaacttt ttttgataca atggttttat tggggggatg
    41161 tggcttttta ctatgtctag taattgcaat ttttcttagt gagaagcgta taaatgtaag
    41221 aaagttagct aaaattgctt ctataccagc tgtttttaat ataaatgaga tgctagtttt
    41281 tggaatacca attgttttta attatattat gtttgtacct tttgtaatta ctcctataat
    41341 tttaaccatt acaagttatg tggctatgtc tacaggcatt gtaccctgta cagtttcagc
    41401 tgtagaatgg acatcaccga tatttttaag tggatatata tctacaggtt caataagggg
    41461 tagtttgttg caattattta atctatgtgt tggtgttatg atttatattc catttataaa
    41521 gatatcgcaa aatagatata catatatgtt taaaaataat atagaaaatt taacaaagct
    41581 agtaaaaagg tatgaattaa caggggaaca gcctaatttt ctaaaccata atggtaaaat
    41641 aggctcaatt tcaaaaatgt tggcatcaga cttgaagttt gctatgaaaa gaggagaaat
    41701 agagattttt tatcaaccac aagtcaatta taatggagat gttgtagggg cagagggatt
    41761 acttagatgg aaacattcga taggagggtt catttatcca ccactagtta taattttggc
    41821 taaagaagaa ggttttctag atgaattagg agagtatatc ataaataaag catgtgttga
    41881 tttaaagaaa agtgaaaagt tattgagaaa ttctgttaag ttttccgtaa atatatctcc
    41941 agaccaactt gatgaaccta agttaccaga acaaataaaa aatatcatta gtagtaatga
    42001 tataaatcct aatatgctag gtatagaaat tacagagcag gttgcattat caggttcaca
    42061 aataattatt gaacgtatca atgcgataca taacttggga ataaagctaa ttatggatga
    42121 ttttgggatg ggacatagtt ctcttatata tcttcaaaat aataattttg atatagttaa
    42181 attggatggt tcattagtta aagagatact tacaaataaa agaagtagtg aaattataat
    42241 gactattgta aatctttcaa aaaatttaga ttttgatata gttgttgagt atgttgaaaa
    42301 tatggaccaa agagataagt tatataggct aggatgtgaa atatatcaag gatattatta
    42361 tagtaaagct ataccttttg aagagtttat agagtatgca aatcaagaaa gagagatata
    42421 attttataag agcttgtaaa ttctagtaag gtatagattt gtaataaaat taagtttagg
    42481 agaaatatat gaatataagt atagtagtag taggtaaaat taaagaaaaa tatttaaaat
    42541 taggtattga tgagtttaaa aaaagacttt ctaagtattg taagttagaa attatagagt
    42601 tggatgatga aaaagctcca gagaatttga gttctaagga aatggaaatt ataaaagata
    42661 aagaaggaaa gaaaatttta gggaaagtaa agcataatag ctatgttata gccttggcta
    42721 ttgatggaaa gagcttgtcc tctgaagaac ttgctaagac catgagtgat ttagcagtta
    42781 gaggtaatag tagtctatgt tttataatag gaggttctct agggctttct gatgaggtct
    42841 taggaagagc tgattatagg ttatcttttt ctaggatgac ttttcctcat cagatgatga
    42901 gattgatatt gctagaacag atttataggg cttataggat aaataatgga gaaccgtatc
    42961 ataaataaat gatacggttt ttgttagttt gccacttaat aatattaaaa taacaaaaaa
    43021 gtattgaaag tatattgtat ttaaggtaga attaaataaa atattataac attataatgt
    43081 ttagagggtt gttaataaaa atttggagga aaatatatga taaaaataat gttgtcctgt
    43141 tcagcaggaa tgtctacaag tttattagtt actaaaatgg aaattgcagc taaagaaaac
    43201 ggtatagagt cgcaaatttg ggcaatacca gaatcaacta tacaaaatga aatagaaaaa
    43261 tgtgacgtat tattactagg accacaagtt agatacgtat tacctaaggc tcaggaaatt
    43321 gctaagccat ataatatacc agtagaagtt ataaatatga tgcactatgg aacagtcaat
    43381 ggagaagctg ttttaaatag agctatagaa cttaacaaca ctaagtaata taaaatataa
    43441 tgtattttta atatatcaat tgggagaatc aaagaatgga tgaaaagatt atagaaatat
    43501 cttttaatat aataggttat gcaggtaaag gtaaaggatt agcctttgag gcaataaaag
    43561 aagccaagaa tggaaatata gaaaaagcaa aagatttatt aaaagagtct aaggaagtta
    43621 taaataaggc acataaatat caaacagaat taatacaaaa cgaagctagt ggaaacaaga
    43681 ctgaaataag tgttatactt atacatgcac aggaccactt aatgaatggt atgaattttc
    43741 aacagttggc tgaggaaatt gttgatttac atttaaagct acaagataaa taaaaattaa
    43801 agaaaataaa ttaagagagt tcttaaaata tacattatgt gtagcacact aattgttaga
    43861 ttattgttta atatttggtg agcaatacat taagtttatt ttgaggactc tttttgtatt
    43921 tagtttaaag ttaatagata tttattatta ataatataag attatatgtt ataatattat
    43981 aacatataat ttaagaggtg aatcatgtta agaaatcaac cattatatat acaagtcgta
    44041 gatatattaa agcaaaaaat attaaataac gaatataaaa ttgatgaaaa tattccaaca
    44101 gaaagggaat tagagcaaga gtttggtgtt agtaaaatta ctattagaaa agctattgag
    44161 atattagaat cagaagggta tgtagagaaa aaaagtggaa aagggacaaa agtaataagt
    44221 aatagccttt ttaataagct atcaaaagcg gagtcttttt caagcatact tttatctaag
    44281 ggacataagt tatctaaaga gactatttca attgaaaaaa taataaacga tacaagttca
    44341 caagtattta gtatatttgg agaaaaatgt agcaagatta ctagaatgta ttacttggat
    44401 agtaagccat atatattttt tactcattat ataccttttg atgaaaatct aactgttgaa
    44461 agttttaata atgaaagttc tttatatatg tatttatata ggagaaatat aaatataact
    44521 agatttgaag atgaattttt tatagaagaa tcagaactag aggtatcaaa ggctctaaat
    44581 ctagataaag acatattatt aggaagaaaa agaaagacct atgatgagag tgacaatata
    44641 gttgagttat catttgcaag atataataca gaagtacaaa attatgtaat taaatatgaa
    44701 atataataag aatcctgagt ttattaaaat gataatatac tcaggatttt tatttagttg
    44761 taaaaaataa tattataaca ttataatgtt tacaaacaaa cattataatg ttataatatt
    44821 tttaataaat aagtgatatt atcaattaca taaaaattag tttgtattat gaaatcgtta
    44881 ttgcattata aataaaggat aatatcaata atacaggggg ataactatgg aaaaattcgc
    44941 aagtttttta gagcgcaaga ttatgcctgt agcagcgaag ataagtaatc agagacatat
    45001 gagagctgta agagcaggta taatagcaac attaccacta acaatagtgg ggtcgttttt
    45061 cacaatatta ttaaacatac ctattgatgc ttatatggat tttatagctc catttaaagc
    45121 aaccttagac ataccattta gatatactgt aggattttta tctctatatg ctacttttgg
    45181 gatagcatca tcacttgcta aaagctatga tttagacacg acaggtgttg gtatgcttgc
    45241 agttatggca tttttagtct ctacaatagt tccaactcaa gtagttgaat cagtaggtgg
    45301 cgttatagaa gctggtagat ggatggatat ggcaaaactt aattcgccat cattatttgg
    45361 agctattgta acatcattaa ttacagttga aatatatcgt tttatgaagg aaaagaatat
    45421 tacaattaag atgccagcag gagttccagt agaggtttca aattcattta ctgcattatt
    45481 accaacagca gtaatcttaa tgttattctg ggtaataaga catattctag ggtttgatat
    45541 aagtgctgca ctaagtgcta tgttatcacc tttaaaagga ttcttatcag gaaatagttt
    45601 aggtggtggg ttactgacag tattcctaat aactttattt tgggtacttg gaatacatgg
    45661 tccagctata atgggaccag taataagacc tatatgggat atgtctatag cagaaaatat
    45721 aactgcattt acagaaggag tatcatctca tgcaatgcca aacatattta cagaacaatt
    45781 tttacagtgg tatgtatgga taggtggagc aggagctact cttgcattag ttgtaatgtt
    45841 tatgttttct aagtcgcaat atctaaagag tttaggtaga ttagggtttt taccagggtt
    45901 attcaacata aacgaaccta taatatttgg agcgccaata gttatgaatc caatactagg
    45961 gattccattt ataattggac ctataataat gacaattcta tcatatgttc ttactattac
    46021 agggattata cctatgatgg tagcaagatt accgtttgca atgccagcac cgatagcagc
    46081 agtaatgagt actaactgga gtatactagc aggtatctta gtattaatca actttgtgat
    46141 atcatttgct gtttattatc catttttcaa agtttttgaa aagcaacaat tacaaagaga
    46201 acaagaagaa atgagcgaaa atttataaaa atacatatac atagaagttt tttactatat
    46261 aaaatataga aaaaagctta taagttatta aaggtgaagg taggaggaat gaccttcgcc
    46321 tttaatttta tatattttaa ataatgtgat ttgaggagga gaaatatgga aagacgatta
    46381 gggatatcag tatatccaga gcatagtaaa atggaagatg ataaggcata tataaaaatg
    46441 gcttcaaaat acggattcaa aagaatattt atgtgtatgc tttcaattac aagacctaag
    46501 gaagaagtta aaaaacattt taaagagatt ataacctatg caagagagtt aggatttgaa
    46561 gtaatccttg atatagctcc aaacatattt gatatattag aaatatctta tgatgattta
    46621 acattcttta gtgagttaaa tgctagtgga ataagacttg actatggata tgatggaagt
    46681 aaagaagcta tgatttcttt caatccatac gatttaaaag tggaactaaa tatgagtaat
    46741 gatgtagcat acttggataa tataattact tacaagccaa atgtaaacaa tatatatggc
    46801 tgtcacaatt tttatcctca aagaggtaca ggcttgccat atgatttttt tgtaagatgt
    46861 tcaaatagat ttaaaaagta tggaataaga actgctgctt ttgttaattc aaaatatgca
    46921 acaatcggac cttggaatat aaatgatgga ttgtgtacgc ttgaaatgca tagaaactta
    46981 gatattgcta catcaactaa acacttattt gcaacaggat tgattgatga tgtaattgta
    47041 ggaaatgcat atgcaagtga agatgaatta aaaagaatgt ctgaagtaga tagataccaa
    47101 gttgtattta atgtagtagc taaggaaaaa acttctgaaa tagaaaaaac aataatggta
    47161 aatgagcaac actttagaag aggggatata actaatcagg tagcaaggtc tacagaagta
    47221 agaaaaaaat atgctaaaga aaatttccct aagcatgata atactaacat ctttaaaaga
    47281 ggagatgtag taattggtaa tgatgacttt ggaaagtata aaggggaatt acagttaata
    47341 cttcaagatt gtacagatga aagaaaaaat aaggtaggta gaataaaaga agacgaaata
    47401 atacttttag actttattga accttggagt aaatttaaga ttattttaga gggagagtaa
    47461 agtgaagata gacatattaa taaaaggtgg aaaaacagta gataaaagta taatagatat
    47521 agctatatta gacgataaaa taatagaagt aaaaaatcag atagatgatt ctaagtatca
    47581 ggcaaaccaa attataaatc tggatggaga gaaatttatt agtgcgggtt ggatagatat
    47641 acatacgcac tgctacgaaa gactagacct ttataaggat tatccagatg aggttggaat
    47701 aaaaagtgga gttactactg tagtagatgc aggaacaaca ggagctttag atataggtaa
    47761 attttatgaa gatactaaaa agtataaaac taatgtatat gctttaataa atattgctaa
    47821 gcagggaata acatctcaag atgaactttc aaatatgatg aatattgatg aagatgaact
    47881 taaaaatgcg gttaaaaaat acaaagattt tgttgttgga atcaaagcta gaatgagtaa
    47941 aagtgtcgta atttcaaacg atattaaacc tttaaaagta gctaaaagaa taaaaaacga
    48001 acttaactta cccatgatgg ttcactttgg gagttctcct ccaatgatag aggatatatt
    48061 cgactatatg gaaaaaggag atatattaac tcatatatat aatggaaagc caaatggaat
    48121 acttagaggc aatgaggtta aaaaggaaat tatagaagct agagaaagag gtataatcct
    48181 tgatgtaggt catggaactg aaagttttag tatggatgtt gcaatgaaat ctaaggatgc
    48241 agagattttt ccagatacta taagtacaga tatatatatt aaaaacagaa taaatggtcc
    48301 agtatataat ctatctacaa caatggaaaa gtttatctat atgggttact cacttgaaga
    48361 tataataaat aaagttacta agaatgcagc aaaagcaata agtttaaaaa ataaaggttt
    48421 aataaaagaa ggatatgatg ctgatttaac tatatttgat gtggttgatg aagaaaaaga
    48481 acttcaagat tctttgaata agtcagtaat tacaagtata tctataaaac caagagcagt
    48541 agtagtcaat ggagaatatt taaatatagg taagtctata cgagagaatg agtagaaggg
    48601 agaaactatt gtatgagtag catatttgaa aaatactctg taagacgtgt tataaatgct
    48661 tcaggtaaga tgactatact aggagtatca acagtagata aagaagttat tgaagcaata
    48721 ggtgaagggt gtaaaaattt ctttataata gaagaacttg taaataaaac aggtgaatat
    48781 atagcaaatt tattagggtg tgaaagtgca caatagtttc tagtgcatct gctgggattg
    48841 cacagagtgt gggggcaatg atagcaaaag atgatatgag tctagtttat aatgtaaata
    48901 atcctaagaa gcaagttaaa agagaaataa taattccaaa ggggcacaat gttgattatg
    48961 gagttccagt agaagtaatg ataagacttg gaggaggaga agttgttgag gctggttatg
    49021 ctaatatgtg taacaaggaa catataataa gagagataaa tgaaaataca gcagcaatta
    49081 tgtacattaa atctcatcat tgtgttcaaa agagtatgtt aagtgtgtta gatgcagtac
    49141 aagttgctaa agaatataat ttacctttga tagtagatgc agcggcagaa gaagatttaa
    49201 atgtatacta tgaattagga gcagatttag tgatatacag tggtgctaag gctatagagg
    49261 gtcctagctc agggttagta ataggtaaga aaaaatacat agataatgta aagcttcaat
    49321 caaagggtat aggaagagct atgaaaatag gaaaagaaaa tattgtaggt ctaacatgtg
    49381 caattgagag atatataagt aatgataaag taactttaaa agaaatggag gacaagctaa
    49441 atccatttat agataagata aatactctaa agggagtgag tgctagtata actagagatt
    49501 cagcaggtag agagatactt cgtggagaaa ttgactttaa tgaagatata ataaataagt
    49561 ctacacaaca aattataaat gaacttagag gtggagagat agccatatac actagggact
    49621 ataaggctaa tgaaggtaag attgagattg atataaggag tgtaactgga ggtgatttag
    49681 atataattta taataaaata aaagagataa tagagaagta gagagtggaa taagtgacat
    49741 tataatgatt taataaattg aattttacca atggagggga taaatatgaa ttgtacacca
    49801 caatattata aaaatagagt ttgtttgaat gttcttgcag gaagtataaa aaatgctaaa
    49861 gaagtatatg atgcttgtga tgggcatata ctagtaggat tattatccaa gaattatagc
    49921 actgtagaag tagctattga agatataaaa aaatactcaa aggaaataga taatgcaata
    49981 tctgtgggcc ttggagctgg agacccaaat cagtcaaata tggtatctca gatttctaaa
    50041 gaacttcagc cacaacatat aaatcaagtg tttacaggtg tagctacatc tagagcattg
    50101 cttggtcaag atgatagtat aataaatgga ttagtttctc caactggtaa accaggattt
    50161 gtaaaaatat ctacaggtcc attaagttca aaagaaaaag atggtatagt tcatatagaa
    50221 acagccatag ccatgatgaa agatatggga ggaagctcaa ttaaattttt cccaatggga
    50281 gggcttaaaa caaaggatga atatatagaa gttgcaaaag cttgtgcaaa gcataatttt
    50341 tatctagaac caacaggagg tatagactta gataacttta aagagatagt tcaaattgca
    50401 cttgatgctg gtgtagaaaa agttatacct catgtttata catcaataat tgataaagaa
    50461 acaggtgata caaaagtgga agatatagaa gtactttata aaataatgaa agaattattg
    50521 ggataaattt atgaatatat tagcttttgg tgaaataatg atgagacttt cagtacctgg
    50581 ttataagttt ttaacacaaa ccaatgaact aaattatata attacaggta cagggttaaa
    50641 tatattatct gggcttaaaa actttggata caatacctac atgttgacaa agttgcctaa
    50701 taataatgta ggtaaagcat caagtgcaaa tgtaagaaag cttggagtaa aagatgactt
    50761 tatcacatat ggaggaaatc atataggagt ttactttctt gaaagtggat atggagaaag
    50821 accctcagaa gtgacttatt taaacaggtt aaatagttca ttctgcgaga gtaaattaca
    50881 agattatgat attgataaat gtctagaagg aatggatgta gtccatattt gtggtattgc
    50941 tatgcaactt acagattcag ttaaagagat tgctttagaa ctagctagaa agtcttatga
    51001 aaaggggata aaagtattct ttgactttaa ttttagacaa tctctaaatc cagaaaggtc
    51061 ttatgatgat ttagtaaatg attataagaa aatacttcca tattgtcatg gactgttcgc
    51121 tagttgcaga gatataaata aaatacttaa tatagataat ctagatataa aatctagttc
    51181 agaattgatt aaaaaagagt ttgatataga tattgtagct ggaacgatga gaagatttga
    51241 tgatatgaat aatagattta taaagggata tatatcaaat gatgatggtt attttgaaag
    51301 caaggagtat aagttagaaa tatatgacag agttggtgct ggggatggat atgtcgcagg
    51361 aattatatac tcatatttgg aaaatatgag taatgaagat atagttgagt ttggggttgc
    51421 tagttcagtg ttagctcata caacttatgg ggataattct ttagtaagca caagtcatgt
    51481 acttagattg atgaacaatg aaaaaataga tatattgaga taacaccttt atatagaata
    51541 aaatttttat ttttttcaga gtcacctttg acttgcttat atttgttaaa catagttctt
    51601 tttagtgatt atgaatatta aattaaaagt taaataataa aatagtagaa aatagcatta
    51661 accatagaaa aaatggttaa tgctattttt atagtcaaga ttaattaatt ttatattata
    51721 gaaatgaact tttctaatgc tggatttgta ttttttttat tccatacaac tacaacttca
    51781 attctatttt ctacttcttt tataggtact attgcaatat cacgttctat cattgtatct
    51841 gtaacgcaaa atgaaggtaa aatggatata cccatgttag aagctaccaa tgattcaata
    51901 gtattaagat tatttgaacg ttgtaccaca ttaggtacaa accccgcttc acgatatcta
    51961 ttctgtatca ttgacttttg tccatactca tcccctgttt cctttacaaa aataaattta
    52021 tcatgttgta attcaattaa atcgatagaa tcctcattgt aaagtggatg accaggaggt
    52081 aaaagagcta ccaaagaata tctttctaca gttttatgtt caaaatcttt taatggttga
    52141 ttttctggat taataacaaa agcaaggtcc atagaattat tttttactaa gtttaaaagt
    52201 tcggttatct cattagtaca aatatccata gatatattag ggtatgtatt agaaaattct
    52261 tttaaatatt gttgaagttt gtttttttcg tatcctatta aggttccaat gctcaaagtt
    52321 ccaaaaaaac catgtgcaaa ttgttgtgtt tttgcaatag catcattgat attttttatt
    52381 atagtgcgtg cctcagataa aaaaactttt ccagctggtg ttagttcaac atggcgttta
    52441 cttcttgtaa atagagttac atttatttgt tcttctaaag attttatttg ctgtgtaaca
    52501 gcagtttggg aaatataaaa tttttctgct gttttggtaa aacttagatt ttctgctaca
    52561 gatataaaat attctaattg tttagtattc aaataatcac ccctatttaa acttgattgt
    52621 ttgtaaacct tatttatata taattaaaac ttattatagt ataagaaaat ttacttttaa
    52681 agaatattgg aaaatatttg tataaaaata tatgttttaa gtatttcttt gtgttagatt
    52741 ttataaattt attaataaga ataacttata tattcccatg aaaacgatat tggatttaag
    52801 taagtttgtc tcataaaatg aaagtatatc aattgataat acttcaaata agaagggaga
    52861 aaaaatggaa gataaatttt atgcaaaagg caaaggaaat aatggatata ttaaaaatct
    52921 tgaagtttgt tccttcaata acttggatgg aacttgtgga atgtttcaaa tggctctgta
    52981 caaaagagat gaaaaatact atttatatgg atgctgtttt ggaggaaata aaaaaaatgg
    53041 agtaatgatt agtgatatta cagaccctta taatccacaa tttataaaac attttcaaat
    53101 gttagaccct aaagagtatc ctacaacaac aactccaaaa attcaaatag cagatgattt
    53161 aatgatagta gcaatgagtt gtggaagtgg gccaggagca cttgttgacc aggctaaatt
    53221 agcaaatatt aagtgtgaag caggaattag aatatatagt ttaaaagaag accctttaaa
    53281 tcctaagttt ttaggatatt gggattgtgg tttaaagcat gtaatgggtg ttcatagatt
    53341 catgtacaat ggtggaagat atgtacattt atcaagtgat tgtgttggct ttgaaggcct
    53401 ggtttacaga gtcatagata taataaatcc tactaatcca gtggaaatag gtaaatggtg
    53461 gagaccagac caatatgcag atggataccc aaatagaact tttgatgcag gagcacctca
    53521 ttgcccagaa tttatggata aaggatggct tcatggacct ccatttgtaa gagatggaaa
    53581 agcatattgt ggttatggag gagctggttt aattatatta gatgttgaag atttaacaag
    53641 accaaaatgc ttaggtgaat tgccatttat gcctgcattt tctagtagac ttgcaggtgc
    53701 aagaactcat acagcattac cattgccagg aagagattta gtcgttgtcc aaaatgaggg
    53761 agaacgattt caattcttta aaccagataa tattacagat gttcaagcta tgaataatat
    53821 acatatggtt gatgttagtg acccaacaaa accaacatta attgctcaat ttccatatcc
    53881 tgaagtgcca aaagatttcc cttatcctaa ctttaatgtc gcaggactag gaaaaccagg
    53941 accatttggt ccacataatc ttcacgaacc aatggataat aagtcatggt tagagcaaag
    54001 aggagataga gtatattgct gttatttcca tgcagggtta agggtttatg atgtatcaga
    54061 cccatattat atcaaagagc tagcatattt tataccacca aatccaaata aaacaccaga
    54121 agagtcttat ttcccaggat ttctaggacc acgcttggca gtaacagaag atattattgt
    54181 tgatgataga ggctatatca tcatagatgc tttagatgat ggattttata tattaaaaat
    54241 gaaagaagat taaataagta ctaaagaggg agagttgaaa atgaaaatac taggtatttc
    54301 ttttggaaca aaaaatggaa ataatgacac aatgtgtaaa gttgcactta aaggtgccaa
    54361 agaagcaggg gctgaagtag aatttattca aatgtcatct attaacatta aacattgtac
    54421 tggatgttgt gcgtgcgtta agactttatt atctggaaaa ggtagtatat gtgtattaaa
    54481 agatgatttt gaatggttgc ttgacaaaat gaaagatgca gatggtatag tagtttcaga
    54541 ccctattttt gaagaagggg catcaggatt attccatact ataatggatc gttttggacc
    54601 aagagcagat agaggaaata atgttatagg gacaaaagtt gcagaagcta caggaggaaa
    54661 aattccagat tcaagaatgc ttaatgataa agtaatatca tttatgggaa tagggggttc
    54721 tgactggggg acgagagttc agtgtgaaca tgctatgcta gctctaatac caatgtggaa
    54781 agttatagat aacgcttggt tcccatgggc aaaggaatta gtaatggatg atacaaagct
    54841 tgctcaagtt cgccaacttg gtttaaatat agttgaagca gcaaaagatt ttgaaaaagc
    54901 ttcataccaa ggagaagaag gtgtatgtcc acattgccat aatagattat tctacattga
    54961 gccaggtact aaaaaggcaa tttgtgctct atgtggtata gttggagaat tagatactat
    55021 aagtggaaaa actatattta gttttccaga agagcaatta ggtcatgctc atgacacttt
    55081 accaggtaag tttatacatg gtgatgatat taagaaaatg gaaggtcatt atgcagaagt
    55141 tcgtaaaaca ccagaattta aagaaagaaa aacagcttat aattttatag aaccattaac
    55201 taaagaaaag caagctggag cttcattaag ataataatta aaatactaag actctttttt
    55261 aagggatgtt ataggaggct tattgtatga atgaaaagcc gagctttaaa cagattgaaa
    55321 ttattttagt agttatttgt ttagtatttg cacattacaa tgttagatta actccagaat
    55381 ttattgctat aattatacca ctatacttaa gttattttat agtatctatt attgcaaacc
    55441 aaatagcaat taagctatta gagataaggc aaactaggga agctactagt tacaatatag
    55501 gaaatggata gaaagaaaaa agaaatatta acactgtcca tgggtattgc tttactacct
    55561 cctttatggg cagtattagc accttatata ggaataaaaa ctggagctgt agcactaatc
    55621 tgtgcaggat tatatgtaac taatggtaat aagcaaaaag atggattaaa aataatgttt
    55681 ggtttttggt gtggggattt atgggcagtg ttagccattt taattatgga atatatgaac
    55741 ttcaatcaaa acctggaatt atttttaaca cttagtatat taggtttttt tgcagttgta
    55801 attgcatcct catttgaaaa aataattttc ctaccatcat ggctttgtgg ttgggctata
    55861 ggtctaacta ttatgacagg tgaaaatatt attaatttac aagatatttg tattcaaatt
    55921 gctatagcta tggcagtagg aatttggtat gtgggtgtag gtgtagattt gtttacaaga
    55981 tatattttga gtaaggataa gaaaaagtta aattgaaagc atgtgaatat actttggtta
    56041 taggagaatg gttatgggtt ttgaatttaa aataatgaga agtttaatat atgtaggact
    56101 tgccaaggaa gaatatagac ctaagttaat ggactggtta tatcgtcacc atattccaga
    56161 tagtattagc acttttggac catattgtac taaatatgcc ttttatcaag catatcctac
    56221 accaaatgaa ggtgagcgtt ttggtgcacg taagatgcag ctaacagaac attattggct
    56281 tgtagatgag catatgcctg aaatggcaaa tagaattatg acagaatata tgcctatgga
    56341 tgttctacgt tggcaaggat gtataccaga tatagaaaat aaaagggttc atgaaaatgc
    56401 agaaagtgga gatgcaggac gtgcagtggg tggagataac ggatgtccac catttatatt
    56461 tgcatttgtt ccaataaact gggaagaaga ttttagagga aaaggacgta ctgtacaaga
    56521 tggaccaaac tatcgttggc aatttatgat taagtatcca gatggtgttt ccaaagaaga
    56581 aggagaaaaa tggttctatg atgaggtagt tccatacttt acaaactgtt gctatgttaa
    56641 tcgttttgtc agtagtaaaa taatgattaa ttatggagca actgcttttg accgtgtagc
    56701 agaactatgg tttgaagggg aagaagagtg gtataaagct gtggttgaag aggcaaaatc
    56761 gtttattaaa aagccagaat gggcacaaga agaggagttc ccatatttaa aaccacaatt
    56821 caatatcgca tcagtatttt taggtgatat agcaactatg gatgcatact cacagtatcg
    56881 tggatatatt ccaatgagat aatatagttt atggtaagta gaggaggtac ttgctattac
    56941 tagagaaaaa gacttgttgt agctttaaaa gtaggtgaat atataatttt aaaataaatt
    57001 tataaaaact aagattaata aatatgagac aatagcatta gaataatttg atatatttgt
    57061 taaaagaata tttagaatgt gtttaaatat gaagatgttc cttttatgat gtcagatagt
    57121 tgaaacaata aaactgttat catgaaggga atatttttat gtctaggaaa tcatttaaaa
    57181 taaaaattaa atgtgtttaa tgacatctta aagtaaaaga aatattgtta gaaatatgta
    57241 gataatatag tatttataat gtattatatt aacaagttta cacttggatt ataaaataaa
    57301 aagagtgatt ctaaaggttg taaatactat actgactttg atacttcaaa gtttagataa
    57361 tgctgtagtt gttaatagaa atacgtttaa tgagcataaa taatttatct aataagtagg
    57421 aaaatataat gtatgtaatt ggacaagtac ctaaattttt aggaatgttc agagacatac
    57481 taaaatttta tgagggaaaa gattagttaa gaacaggagg aatagatatg gttttattga
    57541 ttgttgatac acaaaaatta ataacaaatg aagagctata taattttaat gaatttgtag
    57601 taaatttagt aaaactaatt gatacagcta gaaaaaaata tatagaagta atatatgtac
    57661 gacatgatga tggaattgat tgtgaattaa ccaagggtaa acatggtttt gaaatatatg
    57721 aagaatttaa gccatgtgat gaagaaaaaa tatttgataa agatgtaaac agtgctttta
    57781 aggaaactgg tctattagaa tacttaacaa ataagaatga aaaagatata attattgctg
    57841 gacttcaaac agattattgc attgacgcta ctataaaatg tgggtttgaa catgggttta
    57901 atataatagt tccatcttat gcaaatacaa ctattgacaa ttcattcatg tcagcagaac
    57961 aatcatacaa atattacaat gaatttatct ggaatggaag atatgcagag tgtatttcat
    58021 tagatgagac acttaaaaga atgaattagg taagtatcat tttattatat gagataaact
    58081 ttaactttct tagtttaaaa tattaaagtt aaaaggaaca tttattatta gatattttat
    58141 ttatataaat taattgaaga aaaaaggaat taaactacaa gttaaaaaat aaatttaata
    58201 cattagaatt ataaataagg cacatcaatt ttttttatat taatgtgctt tttatttata
    58261 gtaatttagg cataattagt atcgttttga ttttttaaat aaatttttct tgagtttctt
    58321 tacctaaaga aacctttttt atttataaaa tatataagtg taatatagta tctattttaa
    58381 ataagtttaa tttttgtctc aatctaaaac aaaagttata cttaaatgaa attgaaaacg
    58441 ataaaattct caaataaaat aagtattgtg gaggtgataa aaaaatccaa tgataatatg
    58501 aagactaatc ttaataagaa agtagggatt aattatagtg gacaaagaaa ttgtatcaat
    58561 tctccaaatt ttattaaata gcacattgat tacgactaat ggattacaag aggaatctaa
    58621 ttcatcaaag agacaaatta cttatagaat aaataaaatc aatgacatgc ttaaagtaaa
    58681 aaatgtacca cttatatgtt taagagctga taaagatatt atcgttagaa aagaaacaaa
    58741 aaaagcaatc aaagaaattt tagaaaaaaa ctattctaag aatacttatt actttagtaa
    58801 agctgaaaga cttttatata tgtatttaat gctttttatt aatatggagg atatatcaat
    58861 taatcatttt ataaattcta taaaagtaag caggtctact gtaaatctag atttcaaaga
    58921 tttaatacca aatcttgaaa aaaagggcat tgaggtcaag aacaatcgta taaatggtta
    58981 ttacttagtt ggaaatgaaa tggaaataag gagagtgctt attaagagta ttatagaaac
    59041 cttgtctaat gagaaaagtt caagagtatt tgatattttt attaaagaat ataatttaga
    59101 cagttttgaa gaggataaag aaattatatt gaagttaata aaaaaatatg aaattacttt
    59161 tgttgaagat agattaatag aatttatata tatatttatc tttctaaaag caaggatgta
    59221 ttcaactaga atagttactc atgaaaatgt agatattcct aatattgcag ttatgagttc
    59281 aatgaaagag tataaatttg ctaaggaatt attagaaaca tatgagagtg aagataagat
    59341 aaagtctcat aatataatgt atattagtgc ttggatttta ggtatatcag taggaaatta
    59401 tgaagaagat acagaagata aggatgtaat ttcaaaaatt gtaaataaaa tgatgacaaa
    59461 gtttggatat ttaagtggag tttactatat aagtcaagaa aaaatattta aacaattata
    59521 ttctcatttt agaccagcat actatagact tttatttaaa ttacctatct ataatccgat
    59581 ttgtgaaaaa gtaaaagaag aatataaatt agtttataga attgtaagta atgcaatgaa
    59641 agagttttgc ggattatttg gagaagaaat tcaggaagaa gagttagcat atcttacaat
    59701 gcactttgca accctttttt caaataaaaa agaatttgat ggttttagaa aaagaatagc
    59761 attaatagtt tgttcaaatg gcgttggtag ttcagccatt ttacatgcag aacttacaaa
    59821 cttatttcct gatttacatt ttataccaat gtcggaatca gttggattgg aaaatatgag
    59881 tgagcctgta gatattgtat ttactactaa ttataacaca gagggtttaa aaacagatgt
    59941 gccagtaatt aaagtaagcc ctgttatgac tacaaaagaa aaatataaga ttacacgtga
    60001 agtgtatatt caattaggtg atattttttt aagacaacct aaaatagatg aggttatgaa
    60061 tataataaaa aaatatgcaa atgtaacttc tgaaagtatt ctttcaagtg agttattaac
    60121 ttattttaca cagatagaga attttacatc taaagaagga gaggggccta tgctaagtga
    60181 gattactaat gaaacactag taaaaataaa ggtaaaagct aagaattggg aggatgctat
    60241 tagacagtca gcttctgtat tagttgaaaa taacaaaaca actgaagggt atgtagaggc
    60301 tatgattaat tcagcaaaag catctggacc atacatagta attacaaaac atgttgcact
    60361 tccacatgct agaccagaag ctgggtcaaa agagattgca ataggtattg ctactttaga
    60421 tagtcctatt gagtttggga atgatgaaaa tgaccctgta aaatatgtat tttgtctaag
    60481 tgcaatagat aacaatagcc atctacgtgc tatgtctgaa ctggttgagc tattggaaga
    60541 agaagagttt tttaaggttt tagatagtgc taaagaaccc aaagaaatta ttgattatat
    60601 aaaaacacac gaattataaa ggagaattta attatgtata aaattttaat tgcatgtaga
    60661 gcaggagttg gctcaagttt aatgttaaaa ataaagactc aacaaattgt taaggaaaat
    60721 aactttccaa ttgaagtaga acatggttca ttagattcat taaatggatt caatggagat
    60781 gctgtagaaa cattaattga tgttgctgaa gaattaaaaa ataaacattt gaagtttgat
    60841 ataattggga ttcacaatat tgttgaccgt aacgaaataa agacagcact agaaaaattc
    60901 cttgcttcaa aagagggata aatttaggat aataaggagg aatatttatg gaatttatta
    60961 ttagtttgct gagtacacct gctgttttgc ttggtgtagt tgcatgtata ggattgattc
    61021 ttcaaaaaaa atcagctgtt gaagtattta cagggtcttc aaaaacactt ataggatttt
    61081 taatatttgg tattggtgcc tctgctatga caggagcact tcaaaatttc aataaattgt
    61141 tccaacatgg ctttggaatt actggtgtta tagcttcacc agaagcagct acagcacttg
    61201 cacaaggtac atatggtttt gcagtttcgt gtacattaat tcttggattc atattaaatt
    61261 tagtatttgc gcgtattaca aagtttaaga atattttctt tacgacaggt cacagtttgt
    61321 tcttttcttg tgtattagtt ttaatcatga aagcacatgg attcgataat acaatcacta
    61381 ttttaatagg tggaactatc ttaggattta tgtctgctgc actacctcaa ttctgtcaac
    61441 cctttatgcg tgaattaaca ggtggtgacg aacaagctat tggtcacttt aacatgattg
    61501 gttatggtct atcaggttat attgggcgtt tattttcgaa acataaagat gatacaacag
    61561 aaactataga atttcctaaa tggttatcaa tattcagaga tttcttaatg ggtctatcca
    61621 tagttatgtt aatcttattt tatattgcaa cattaaaagc tggtcaagca tttactcaag
    61681 aaattgctgg ctcaacgcat tggttagttt tcccacttat agaggcattt acatttgtag
    61741 caggtatgtc aatattgatg tcaggtgttc gtatgttctt agctgaaata actgcagcat
    61801 ttgtaatcat ttcagaaaag tatattccag gttcacgtcc tgcactagat gttccaacag
    61861 tatttccata tgcaccaaat gcagttatta ttggatttat cacagcatat gctgcaggtc
    61921 tattagcaat tgctattatg gcatcatttc ctagtatatt tcctgtagta attattccag
    61981 ctgctcatat atgttttttc tcaggaggta cagctgcaat atttggtaat agttcaggag
    62041 gatggagagg ggctattgct gggtcatttg ttgtggggtt attacttgca tttttaccag
    62101 ttatactata tccagtttac gggactcttg gtatagaggg tgcaactttc cctaatattg
    62161 attataacgt agttggttcg atattacata atattttaca atttataaaa cctatttaaa
    62221 ctaaattata taaagatata gtcatagtca ctatatttta aggaggatac attttatgga
    62281 aaatacatta tctgaatttt tagataatat atctaatgaa ttgtcagaat ttattgcctc
    62341 aatagatgag acatccataa ataaagcatg caatttaatt tttgaagctg aaaaaaatca
    62401 tggacgtgta catgtgactg gtatcggcaa accaggacat gtatcaggat atatttcatc
    62461 attgctttca tctactggaa caccagcata tatattacat ggtacagaag cagtacatgg
    62521 atcaagtgga caagtagttg aaggagatgt tgttattgca atatcaaata gtggtgaaac
    62581 tcaagagtta aaaggaactc ttgaaacact aaaaataaat ggagcaaaga taattggtgt
    62641 aagtggcaat gagagttcat ttttaaaaaa tatttctgat atcttcttgt ttgcaggtgt
    62701 taaacaggaa ggtgattgcc tcaataaagc tcctcgtgct tcaattctag ctgaaacaat
    62761 agtattacaa tcattgagtg ttgcactaca gtatgctaaa ggtcttaata cacagcagta
    62821 tttgaagtgg catccagcag gaagtcttgg aaaatctatt agagagggaa tataatttta
    62881 tgaaatataa aggaattata tgtgcaatga taacaccatt tgatgaaaat caaaatatca
    62941 attcacgagc aacgtgtcaa ctaattgatt atttgattaa aaatggaatt tatgggttat
    63001 tcattttagg cactaatggt gaatgtcatg tgttgacaga tgatgaaaaa gttgaatttg
    63061 caaaaattgt tattaatcat acaaataatc gtgtgcctgt ttttgttgga acaggtggca
    63121 attcaactcg tgaagttata gatttgtcta agagaatgga agcggttgga gcaagtgcat
    63181 tatctattat tacaccatac tttgttacac caacacaaca ggaattaatc ttgcattacg
    63241 aaactattgc taattcagtt aatttaccta ttataatgta caacatgcca gacaagactg
    63301 gaattaacat tgaaccagag tccgtgtgta aattgtcgaa gataaagaat attgttggaa
    63361 ttaaggatag tagtggtaaa cttgacaaca tgaaagctta tattgaagta actaagaatg
    63421 aggatttcag tgtattttca gggtcagatt cacttatttt ggatagtcta aaagctggta
    63481 gtcaaggtgc tgttgcagca acagcaaact tccttacaaa gattgatatc tctatctatg
    63541 aaaactttat gagaggggat ttggaagaag ctcaaaaagc tcaaagtagt atagaagaat
    63601 ttcgacgtat cttaaagctt gggacaattc catctgttct gaagaaaact attgtattga
    63661 atggaattga tgttggaact gcacgacttc ctgtaattga accaactgga gacgcacttg
    63721 aagaaattaa aaacgtagtt gaaaattata gagaaatgtt ttaataaaag tagtgagaac
    63781 agataacata actggcggaa gttacattag tatataatta atatatgtat tataaaatat
    63841 ggctaaaatt attggatagg taaagtggtt tgatgagtat agaggtgata atatgaaaaa
    63901 gatgaatata accaaaagaa tggcagaatg tggtgctctt gcaattgtaa gagaagaaaa
    63961 gcttaaccgt gcatgtgaaa ttgtggaagg ttgtataaaa ggtggtataa cagttgtaga
    64021 aatgagttat accctgaata atgctggaga aataattcaa ggacttaata aaaagtatgg
    64081 tgaagctctt tgtgtgggag caggaacagt tttagatagt gaaacagctc gtcatgctat
    64141 attacatgga gctcaatttg ttatttcacc aaattacaat gaagatgtag cgaagatttg
    64201 caatagatat cagattcctt atgctccagg atgtacatca ttgactgagt ctgtagaggc
    64261 actgagttta ggagcagctt ttataaaagc tttcccaata tcagatttct atggacctaa
    64321 actagtaaaa gtatttaaga caccaatacc tgatatgcca gttttagcaa gtggaggaat
    64381 taaccttgaa aacctacatg tatggttaga aaatggggtt gacgtttgtg gatttggtgg
    64441 tttattaact aaaggtacgg ttgaggatat tgctaaaaat gctaagaaga ttcgtgaaat
    64501 cattaaaaat ataagagaag tttaatattg ggtttgtatc atagcagttt ataattgcta
    64561 tgatacaaac cctttagtat ttgttatctt aatttaaaat atagatgaaa ttagtaatgc
    64621 aactatataa ggattgctaa tcaatatata ttttttatgt atttatgaat ttgtaggtaa
    64681 gtacaaaaga taaatatttt atttataaat ttactttatt gtttgttgtg aaacatcttt
    64741 tagcctatat ttatgacctt cattgatact ataaactaat gctaaagtca taattataga
    64801 cagaattatt aaaataatcc aagccatctt gtaagaacca gttaagtcaa agatgcttgc
    64861 aatagctggt gtacctataa ttgagcctat acaagtgcaa gaggccacaa acccatatat
    64921 ttctggataa tgttttgtac caaatattct acttgttaaa acaggggtag ttactgtacc
    64981 tatacaagtt ccaattccaa agaagaatgt catcaagtaa agcattggtt taaattctat
    65041 aaaaagcaaa caaactatag atattataaa acaaatattg cctaataata ctcctgcctt
    65101 agagcctaat ttatcaaata catgccccaa tacaacctta ccccatattg ctataaataa
    65161 gtacgtagat actattgagg ctgttaaaga agggttatat ccactgtctt ctaaatatgc
    65221 tgggatatga ccaagaatac atccagtaag caatattaaa gtaacaccaa atgtgaaagt
    65281 ccaaaatact ggtaactttt ttgcttcttt aagagagata ttccattcat tttttatagt
    65341 atttttgtta gtattatctt gatgtctatc atatccataa ggttgcaaac ctttgcaaga
    65401 aggaaactga cgaacaataa agattgtagc tggaaccata attaaaaaca taacaatagc
    65461 aagataaaca taagtttgtc tccatccata attagtaatc aacttaacta ctagagggct
    65521 aagtaatgtt ccactaatag aagtaccagc cattgaaaga cttagagcaa gacctctttt
    65581 ttcataaaac cagttagaga ttaatatgga tacaggcatt ttagttgcac cataagtaaa
    65641 aagaccaata aagaatgata ctacataaaa gtggaaaatt gatgttgcta atgaatataa
    65701 accgtaaaat atagaaagcc ctgcaacaca gataacatga attaaatgca tatgtttagt
    65761 agacataagt tttcctgtga tagatgccat aaacatacac attagtgaaa ttatagcagt
    65821 agatagagtg taagcacttc tagtaaaacc aaggtcttca gttatgggtt ttataaataa
    65881 acttgctaag ctaactatag gagcatatcc taaagccatt actataatac atgctaagag
    65941 aatccaccat ccataaaata ttttactatt tttaactgtg ttttccatat tataaactct
    66001 ccttactcat attttttagc cattgatatg cacattgagc atatatagct gaaccgagag
    66061 caagacattt gtcgttgaac attacttttg gattatgggc aacataccat ttagaagtat
    66121 cttctatacc agcacctaag tacataaaac atgtaggaac cttttcagaa atataagcaa
    66181 aatcttcaga acccatagtg tgattaaatt ctgacatttt aatgtttttg tctaattcat
    66241 agatataaga catgaatttt ttatttaatt catcattaca tattaaagca ggtacatttg
    66301 ataaaacttc aatatcagca ctacagcgat aagttataga gacactttgt acaacttcat
    66361 taattcgatt tattaataaa tcccttgtcg ttggagaaaa tgtacgaagt gtaccctgta
    66421 aaactgcctc attggggatg acattacaag cctcgcctga tttaaactga cccaaagtta
    66481 gagttgctag ttcttgaggt ggacattctc tactaatgag ctcttgaaga gctaaatata
    66541 tgtgaacgcc tgtattgata gggtctatac aattttctgg ttgagaccca tgaccacctt
    66601 ttcctttaat ggtaatctta aatccataac aagaagacat aaattctttg ccataaacca
    66661 cagacttatt tggcatagta ggcactacat gcattccaaa tgctgaatct acttttggat
    66721 tctcaagaac tccttctgaa atcatagcct ttgctccttc aaaaacttct tctcctggtt
    66781 gaaacattaa ttttactgac ccctcaagtt cattttcttt aagctttaga atcttagcag
    66841 ctcctagaag tattgccata tgagcatcat gtccgcatgc atgcatataa ttattatttg
    66901 atttaaactc cagctctgtt tgctctatta ctggaagcgc atccatatca ctacgaatta
    66961 atatacattt tccgctattc ttattaccta ttaaacctgt tattgaatag ccattacaac
    67021 caactttata ttcaatgtta aattcttcta attttttttg aataaagttg actgtattgg
    67081 gaagttccat acctatttct ggattttcgt gaaaatgttt tctccagcta ataatctcac
    67141 tttcaaactg ttttgctaaa ttcataaaca tatctgacat atttatctct ccttttaaag
    67201 attttaagtt ttaattatac ttatccaaaa acttgtaatt aatactaagt tgtgttagtt
    67261 ttatgatagc atattaaatt tgtcaatcgg tattagcaaa aaaacatgag gtataaggaa
    67321 aaggttatat caatttataa tatatactag tttaggggga tatgatgaat ttaaattatt
    67381 ttcaatattt agttgaagtt gcaaatatag gctctattag taaagccgca gaaaaaaatt
    67441 ttgtatcaca accatattta agtggtatta tcaaaaaaat ggaagatgaa gtagggtttt
    67501 tgatttttaa aaggacaaat cttggtatag aattaactga aaaaggcgag atttttataa
    67561 atgaagcaaa aaaaatttta ataggaattg aaaatataaa aaatataaat acaaagaatg
    67621 aagaagggtt gtcaatcggt atggtctact ctttattttt tacgaaatgt tttctaaaat
    67681 ttaaaaagtt taaacctaca gacttacaag ataaagtcta tgaaatgagt ccaatggaaa
    67741 tattcaaagc attaatagat aataaaatta ggctagggct attttcctat gcgactaaaa
    67801 aaaaggacaa atattggaat attgctaaga agcatcatct aaagtgttgg agtatatatg
    67861 aagatttaca tccttatgta attatgtcaa gaagccatcc tttagcatta aatgattcaa
    67921 ttacaatatc agatttaaac agtaatcctt atgtagttta tgataaaagc gaatttttaa
    67981 tatatctaga tatgataggt ataagaaagc atccagattt gcttttagtt tcagatagag
    68041 gtagtttttc tgatgcaata ttagataata attatctagg tataaccact tatttttcag
    68101 agattaatga gcaagataac aaatttatat atataaagtt agaagattgt gatgaaacta
    68161 taggaatagg ttatgctata ttagataatt ataaattgag tcaaagagaa aaagatttta
    68221 ttaaatttat caaaaataag taaaatattc catatttaat gtgggtagat tgtcatattt
    68281 caaatcaata aataattagt atataccata taagtaattg cttatatggt tatttttagt
    68341 gaagcaatta ctttagaaaa tgaaacagat aattatgtaa taaataagag atagaatttt
    68401 tatttatcta acattaagta taaaagaaaa ttactatgac ttaataaaat aagatattaa
    68461 caatgaaatt cttgataaat accttttaat ttaggcatta taaagtttaa ttgtacatgt
    68521 gttacatatt ttcttgaaat ttataattaa tattaaactt cctcagttca ataataatat
    68581 actaaattta taagttagta ttattcatat gtaaagctga gtgctttact aatttatatc
    68641 gcataaaatt tcagcaattt tatcttaact tttctatata aaaagaactg ctttaaaact
    68701 tggggtatga tataatttca ttaaaagaag acggttttta gtaaatacta gaaaataata
    68761 tgtttttata gaaaaagtta aatatggatt taagtgaata agaatcaata agtaaggtat
    68821 taaattatga atagggtaca aaacattact gaattaaaag ttttagaggg agaagtttag
    68881 caaggatgtg tgaaaattaa ttctcaaaca ggaattattg tatatgagat aaatttacac
    68941 acattgaaga ttcactttta tttatactaa aaagtagatt gtcttaaagg tgggtctaaa
    69001 gataggagga taatcaaaat aatgaaagaa gacattggat tacatcgaat gtgtaaagaa
    69061 gaacaagtaa caaagaatga agttatttcg gaggatattt taaaatccat gagtatggga
    69121 gtcagtaaac attttttaga tgattcattt acaatactat ggggaaatac atcattctat
    69181 caattatttg gatatacaga agaagaattt ttatttaagt tttctagttt aaaagactat
    69241 tatgaacaga atctttataa ttttgaatct atgaaaaatc attttttaga ggcttatcat
    69301 cgtggagaaa agagtacaga atatcaaatt tgtatttcag caaataatgt agaccctgtt
    69361 tgggtaataa tgaatggtat attaattgaa tcagaagaaa atgaaaaatc aatggtctat
    69421 atattgtatt caagaattaa tgaattagaa ataaagcaag aagaagcatc taagatggaa
    69481 aaagagagta cagagaattt taaatggatg atgtcagagt atgctggaaa tgtttatatt
    69541 agtgatatgg atacatatga attactatac ttaaataagc aatcatgtaa tatcttacag
    69601 gcatcagtaa atgaactcat tggaagaaag tgttatgaag taattcaaga tagaacttca
    69661 ccatgtccat tctgtacaaa tccatatttg aaaaaaaatg acgtatatga atgggaattt
    69721 tataataaaa aactgaaacg aacgtttatg attaaaaatc gtatgttgaa ttggaaaggg
    69781 cgtagagctc gtatagaatt atcttatgat atgtatagtg ctgaatataa attagcaaaa
    69841 aaagatcaag aaagagaatc aattttgaaa accattccag caggaatggt tcgagtagat
    69901 gcaagagatt atcttactat actttggtat aatgatatat ttttgaatat gattgaatat
    69961 acaaaggaac agtttgcaga ggaacttgat aatcaatgtg gatatttatt ttctgaagat
    70021 tataaacgta gtaagaagct agcacaagat ttaaaggagt ctggggataa tgttgtattt
    70081 gaagcaagaa tatacacacg ttcaagggaa gaacgtatat ggaccgttac attgtgttat
    70141 gtcagtggag aagacagctg ggatggaata ccatcttttt atagtatagg tattgatata
    70201 acaaaggaaa gaaaacagat tgagaaatta cagtatatat cagagaaaga tgcattaaca
    70261 ggaatttata atcgtgctga gactgaaagg cagattaaga agtattttga agaaaattta
    70321 aattctatgg gtgcactgtt tatgattgat acagataatt ttaaacagat taatgataca
    70381 gaagggcata tgattgggga tatagtgctt actgagatgg catcaggtat gaaaaaaata
    70441 atgtgtgaca gtgatgttgt tggaagaata ggtggagatg agtttacaat ttttatgaag
    70501 gatatttcct cagttaaaga tgcagaaaag aaagcagaag aattattgta tatgttccgt
    70561 cacctatttc agaaagaaaa aagttctcta aaagtaactt gcagtatagg aatagctata
    70621 tatccaaaag atggtactac atttaaggaa atatatacaa gagctgataa agctctgtat
    70681 caagcaaaaa acataggaaa aaataattat gtaatctaca atcaagattc ttttaaagaa
    70741 ttagaggcat ttaattgttc ttctcttggt acagttattg attcagaaaa gcaatatgct
    70801 gaatgtcctg ataatcttac acgttatata ttccgtatgc tttatcagac agataatata
    70861 gatgagacga ttaatatgat acttgaggtt gttggtaagc agtttaatgt aagtcgtgtt
    70921 tatatttttg aaaatacaga ggatggtcga tatacttcta atacctatga atggtgtaat
    70981 gaaggaatct cttctcaaat ggcttatttg caaaacaaca attatcaaga ctatgaggat
    71041 tatgaaaagc tttttggaga tgaattagtt ttttattgtc gagatatcca cacattaagt
    71101 cctaaactag aagaattgtt ttctagtcaa ggtatccact ctacacttca atgtgcatat
    71161 aaagaagata aagttttcag tggatttgtt ggatttgatg aatgcacagg attacgtcta
    71221 tggtcacaag aggaaataag tacattatca ttgatttctc aaattatatc aatgtttttg
    71281 caacgtaaaa aaaataaaaa atttaatcaa caaatgcaac aatatcagaa tattttagat
    71341 aatattgacc agtgcatttg tgtgattaac aaagaaaata attttttatt gtatgtaaat
    71401 aaaaaattta aaaatacata ttctaaatta caaattggac aaccttgtta tcttgatgct
    71461 gtagatattc ataagatatc cattgcatgg aatcaaaaag aagcatactt atgtattagc
    71521 atgatttagt ggtaaggtaa agtttgtatt gaacttaaac taaatttagt tttaaataaa
    71581 atattatttt ggttgattac tgaaaatact agaatctatg ttaatgaatt atactaattt
    71641 tgtaccacta ttaaaatatt gtttgataaa aataaataaa aatcttaaaa cagttggtta
    71701 taaaaaatta actgtttttt attgttttta tatttgtgac aaaatagaca catgccattt
    71761 agaatgtgac aatatagtag ttgtttaaaa gagatgcaaa gcattatact ttaattaaag
    71821 tatagtgtat ttttgctttt aaaataaaaa caattagggg gagagttata attgaaaaaa
    71881 ataatatatg tattatttac aattgaacta ttaatagtat ctttattagg tctaaatata
    71941 gttaaagata atgaaattaa taatatttta tataatgata caacaagtat atctgtaatg
    72001 tttaaagatt ataaaaagtt caacaaaaat tatagtaatt ggattaaaga tattgcagac
    72061 gaaaataatg tgactatatc aaagtatgtt tttaataata atgaaaaatt atctatatat
    72121 acaactgata caagtttaaa taataatata aagttaaaat caggagaatt tcctaatact
    72181 aacactaatt caaatgaatt tattagtaat ataaacacta ataatagtaa tcaagtaggt
    72241 aaattctcaa ctatgagtaa agacatatca attttgatta gggattttga taaaataagt
    72301 gaagttggag aatcaggaat tttatatatt tcaactcaaa ataaagatac aataaataaa
    72361 atattaaaag agttaaatgt agacagaagt atttttgtag caagactaca tgatagatat
    72421 gttaattcaa atttatactt aaatccttca ataattagag atttaatact aattatcctt
    72481 tgcttcttgg ccacaataat acattattca attagtgtga gtagagaggc ttctatttta
    72541 agattaaatg gatattctaa gttagatata attactagag ttataagaag tatacttaga
    72601 attatgattt tatcatctat cacatcatta ttaatatata taatctatat tttaaaatta
    72661 aatttgggtg ttagagcatg tttatacttt gttatatttt cgattatatg tattttgata
    72721 aatattttta tatctatatt aatagtgggt tttaatatta gaagttctaa atatgtgcta
    72781 actctaaatg gaaaaaaacc ttatggtttt gtaaacataa ttcatttcac attgaaaatt
    72841 gtatttgtat catttcttat attatccata aataactgca ttttaaatta taatattcta
    72901 caaactcagt taggaaatct atctgagtgg gataaagcaa aaaatgttta taaccttact
    72961 cttaaagata caggtgaaca atctttagga aaggaagaag taataaaaaa tgccaagatt
    73021 aaaggatttt ataaaagttt agtagaagaa aaagatgctt tcttaattga tacaactaat
    73081 tttgaaaaac ttgaaaatgg aagttacatg tatgaaataa attcaaaggg taaaaaacca
    73141 gaagtaagtc aatatggtaa aaatataaag ataaataaaa actatcttaa agttaatcct
    73201 atttactcaa atggcaaaga aatatttaat ctaattgact atgacgataa gactataaat
    73261 ttattagttc ctaaaaagtt acaggtacat gaaaatgaga ttaaaaaaga gtttagagaa
    73321 ttattttatt ttgaaaaaat agaagtagaa aatatgtata atgaagaatt aaatagagat
    73381 ttaaataaaa caaagaaatc agatttaaat gttaatataa tatatgtaga taataatcaa
    73441 agctacttta cttataactc acttgttatg gatgacaata ggaatctcat taatgaccca
    73501 atagcaatag ttgacataga taatattgat gattcttttt atctttccta tatatctaga
    73561 tgtgtatatt ttaattctaa gaaattagat gctcttgcag atataagtaa aattattgaa
    73621 gctcaaggtg tagaagcgaa tatccaaagt ttacgtgctg tttacaatga gtatggttta
    73681 gaaataaata aattagaaaa atatttgaat agtgagattt ttactataat aataatagca
    73741 atatcaaatt taatgattac ctacaatata gtagttagtt actatgaaag aaacaaatat
    73801 aagttatata ttaaaaaaat atttggttat tcagctacag ctagaagtat attgttaata
    73861 atttcattaa tattaacaaa tgttattcca ataggcatta tatcaacaag agtagattta
    73921 agcaacaata ttgtcttatt tggacttctt atattagttg tagaagtaat tatatctatt
    73981 atattagaca agattatctc aaatagttca tttaataaaa ttataaaagg agaacattaa
    74041 aaagatgatt tcattaataa atatatcaaa aaaatttaaa gataaatcta taatagacaa
    74101 atttaaccta gaaatttcta agggcgaatt tgtagcgata acaggaaata gtggctcagg
    74161 taagacaact ttacttaata taatgggatt attagaaaaa cctaattctg gtgatattat
    74221 aataaataat ataaaaaatc caaatagtaa acaaataaga attttacaaa gggattttta
    74281 tggttaccta tttcaaaatt atgctttaat tgagaatgaa aatgttgaaa gtaacttgaa
    74341 aattgcttta aagtatcaaa aaaatattaa tcgtgatgaa aaaataaatt acgtacttga
    74401 gtctgtaggt cttggaaaat acaataaaaa aaagatatac gaattgagtg gaggagaaca
    74461 acaaagggtg gcgttagcaa gagtaatatt aaaagagtgt gaagtaatat ttgcagatga
    74521 gcctacaggt aatttagata aaaaaaatag agatatagta tttgatatac ttaaaagtct
    74581 aaataataat ggtaaaacta tcgtattagt aactcatgat ttagagctat cggagcaggt
    74641 agataaaatt ataaagttgt aataatatca attacaataa atatgggaaa gagattacag
    74701 ctaaatcaaa ttcaacaata ctaggaatat aatttaaata ttaaataaat tagtagtttg
    74761 taaatataag tataatatga tattataaag gctcaaaaga aattttatat aataagaaat
    74821 ctaaaaataa taaatggagg acatataaat atggaaaatt taccaaattg cccgaaatgt
    74881 aattcagaat atacttatga agatggaact cttttagttt gtccagaatg ctctcacgaa
    74941 tgggcattag gattggaact agaaggagat tcaaatatta tcaaagatgt aaatggaaat
    75001 gtattaaatg atggagattc tgttacagta attagagacc ttaaagtaaa aggaagttca
    75061 tcagctataa agattggaac aaaagtaaaa aatatccgtt taatccatga ctcatcagat
    75121 ggacatgata tagaatgtaa gatagatggt tttggagcta tgaagctaaa gtcttctgtt
    75181 attaaaaaag cgtaatatta taactaaact atattgttta ttattttcaa gtatagtata
    75241 aaaccataag aatctattaa gtaataaaaa tttacttatt tatctttata ttttcttatg
    75301 gttttattaa atatagattt tattgaatac caaaatattc tctcctctgc aaataagcca
    75361 atcttattta tttaaactaa tatattttgt actatttata ttaaaattgt aaatttaaat
    75421 gctatgttat ttagctttat atagttaatt tacaaatttc tgattttata aattgtattt
    75481 attatatctt taatgctaaa atcattaaaa gtttcaattt ctgtaaagat ttacaatttc
    75541 tcaaatacat tatgaatatg tgaaaaattt attactacaa tactacattt aaaataagta
    75601 ttagtataaa ggtattgtta caagtataaa gaaatttatg tatactattg gaataaataa
    75661 taccttaaat tataattaag aatagaactg ttaaataaga gatttgatta tcatttgatt
    75721 atagataatg tactattaaa aataaagttt aatgaggaga aaaaatatga taagtataca
    75781 taaaaatata tatgatgata agttatttga ggagctaaag attgactgta agaagtgttt
    75841 tggactttgt tgtgtagctc tttatttttc tgcgtcagac ggatttccta ttgataagga
    75901 atcaggaaaa ccctgtatga atttacaacc agattttaaa tgttctgtac atgataatct
    75961 tatgaaacga ggttttaagg gttgtactgc atatgattgt tttggtgcgg gtcaaaaagt
    76021 agcacaagta acatacaagg gtatagactg gatgcaatca ccagaactag caaatcaaat
    76081 gtctgaagta tttttaatta tgagacaact acatgaaatg ttatggtatc ttaaagaagc
    76141 atctgtatta aatatatcag atacaatcaa atcaaaaatt aatttaagaa tcgaagaaac
    76201 tgaaaagata accaatatga gttcagaaca gatagttgat ttggatatca tatcacatag
    76261 agaaaaagtt aattcattat tattgcaagc gagtgagtct gtgatgggaa aggttaaatc
    76321 ctttatcaaa acctctactc ttaaaaacat gaaaaaatta agcaaaaata tagatttaat
    76381 aggagcagac cttagaaaaa caaatctaat aggagcagat ttaagaggta gatttctaat
    76441 agcagcaaat ttaagaaata cagatttgag tggggcaaat ttaataggag cagacttaag
    76501 agattgtgat attagaggtg ctaatcttga aaatagtata tttttaacac aattacaagt
    76561 taatactgca aaaggagatt ctagtacaaa gttgccagtt tcactaatac gtcctaaata
    76621 ctggggaaaa taattaaatt aatacataat tttacaaaat atgaactttt ttgaccttga
    76681 ttcatattat acattagaga ttctttataa gaatttctta atataatata gggagagata
    76741 taaaaatgag ttatcaaaat tataaatgtg aaagagatta tgtgtatgat gattataaat
    76801 acaataagtg taacgagtac tataatgatt atgaggaaat gacacatgtt catgaatatt
    76861 cagaaagtgt taagttagca gaagaatgtg aggatagaca taaccaccgt gcagcaggag
    76921 ttactggtga agttatacca ataaatggag gtacaaatca tgttcataaa ataaatgata
    76981 atgtagattt ccttgaccat ttccataaga tatgtgttac aacagggcca gcaattagaa
    77041 tacctggaac tgataaacac attcacttaa tatgtggaga aactactgtt aatgatggtc
    77101 attgccataa attccttttt actactcaaa tagaagctcc tttagtataa gctgatgtga
    77161 actattgtag taaatttgct agattatagt atataaatgt taaaaatata taatagataa
    77221 tatttaaact taatgaggac tatgatattt aaccttcgta gtcctttcta agttttgtat
    77281 aaagaagtgt tatacaatta aaagtgatat agggaggaaa tttttatgaa atctggaata
    77341 attcttgaaa tgaaacagat aaattcaaca gaatatgacg aaatgttgca agtctgggaa
    77401 tcgtcagtaa gagcaactca tgatttttta acagaaaaag atattaaatt tttgatacca
    77461 ttagttgaaa ttggacttaa agaagtagaa aatatagttt gtataaaaga taatgatata
    77521 ataaagggct ttataggaat agataaagat aaaattgaga tgctctttat agaagataaa
    77581 tatagaggaa atggtattgg taaaaaatta ataaaatatg ctatagataa atacaatgta
    77641 aaatatgttg atgtaaatga gcagaataaa aaagctgtag gattttatat tcatttaggg
    77701 tttaaagcgt tcgataggtc tgaaatagat ggacaaggta acccatttcc aatactacat
    77761 atgaaattaa tttaaagtga tacttctcac ttattcgcaa aaatatttac ttaaattttt
    77821 tatacaaata aaagtcgtga cagtcttagg acacgacttt tttactacac tattaaattg
    77881 aaatttatct gttctatatt atgattatta gatgtagttt ttttatttta actatgtact
    77941 taaataccaa gtatacccat acctatcaag tacttcagca gcaccatcat tttgatgtgg
    78001 tggtgggtgt ggtaaaaatt cttgtacaag cgtaccaccc tcggcaagtt ttatagatat
    78061 ttcttctatc gtttctcgag atggtagaac aacacaaatc gccatgccag aaattacaac
    78121 aggcttgtct gtatccgcac ccattataca accttcatat tttgtgaaag taacacttgc
    78181 gtgcataaca ggattgtttg gattgctttc taatcgtgca aatatagttt ttcctcctcc
    78241 gaaagcctca gcataaaaat taaatgcttt ttcacaagta ccattaaata ttaaatatgg
    78301 agttagcatg acaaatatat cctccttgat atagaataat ttatagttgc acctgataat
    78361 ctaaattctg atttagtaaa ttgtatcata gggaaacctt gatgtatata attttttatt
    78421 attagattat acaaatctat taatttaaaa aaatgttata tgtaaggaag gtttatagga
    78481 taaaatataa taaaaagagt aaggtgacat tataaaaaat gtatattgac attgacgcta
    78541 cgtaattgta tatactttgt cttaaaggag atggtaaata tgaatattat agaaattcgc
    78601 tcagataaaa tatacaagaa gataatggat gcaccaataa acaaaaaaga agatatatac
    78661 atatatgaat tgatgaagcc ttttgaattt aagtggaagt gtatgaatgt tccaatagtt
    78721 gctaaacaaa aaggcggata tgatgtaatt atagcaagtg aaatgttagg agttttatcg
    78781 cctaaggata ttgatgaaaa gcaaaaaaag aacataaata tgttatctac tgataaaatt
    78841 tggaacactt gcaaagaaac catagaaaac tctataaatg cttttataaa agaagggtat
    78901 gatttaaata ttaaggatta taaatattca atattattag ctaatccaaa tagtccttat
    78961 acaatattaa gtgatggata ttggggtgat ggtgggattc ctggatatat atttctatca
    79021 ttggttccta atgaatatac tatcaataga ttaccagtat taatagcaca tgaatgtaat
    79081 cacaatatta gattccagtt tatagagtgg aataataata taacattaga agaaatgatg
    79141 ataaatgaag gtattgcaga aaattttgca aaatggatgt ttggagagga aatggtagga
    79201 ccttgggtca gtagaacaga tatcgaaaca ctaaacactt atataaagcc aataataaaa
    79261 agtgctttaa aagaaactgg atttcaaaat ataacatctt atctttatgg tgatgacata
    79321 gctaaaatgc aaggatattt tccagtaggg ttgccttatt gtgcaggata tgcttgtgga
    79381 tattatatga ttaagtatta tttagaaaag acaaataaat caataatcga agctacttta
    79441 ttgccttata gtgagataat agaagcagta gaagagtttt gggaataaat tttattaatt
    79501 gcatgatttg aaataaatca tgcaattatt ttatttttaa gaaaaaataa attgacaata
    79561 aattataaga aatatacaat aatatatata aagaaatatt tcaatatgta aaagttttaa
    79621 gatttcatat ctagagtacc taacattaca tgttagtttc ttgttactta tctaattaat
    79681 ttatatttca tag
//
LOCUS       DAMKOJ010000005        70116 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000005 DAMKOJ010000000
VERSION     DAMKOJ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70116
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.005"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            54..431
                     /locus_tag="PC592_000429"
     CDS             54..431
                     /locus_tag="PC592_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4054447.1"
                     /translation="MMIRKIPQAELKVIKFIWRVDNTVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDKYTNYAIIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            424..1458
                     /locus_tag="PC592_000430"
     CDS             424..1458
                     /locus_tag="PC592_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF4054448.1"
                     /translation="MNNYMIYVFDNLIKTTIVCSLGICLLLFLKRYVFKKFSKRFNYY
                     IWVVIVFRMLLFLFNYTVIYEVKEPKENIIGNNLIRIDISIDNNFMLYLAYLWLVVTI
                     VIAVYTFVKYTRFKNLVVDVSYDIEDNDVNCIYKNLLKKLNIKKKIELRSSDELISPA
                     GMGLFKSYIFLPDYPYSKDELNWILKHELMHFKNKDILIKFLVFSVKTIYWFNPLVYI
                     MSNKVNLDCELCCDESVLMDCSLEDKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKSGILVLLISFALFSVTYFNFESISFDNSNSLRNIGILEKTGADLKE
                     EDDISVRVVN"
     gene            1520..2122
                     /locus_tag="PC592_000431"
     CDS             1520..2122
                     /locus_tag="PC592_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF4054449.1"
                     /translation="MKSLKKILIVTGCLTIISTSLAFASTNNDVNVSKSNEDQATNSF
                     TITGYEFTYENAPQPIKSDYEKKCKELNINPSKNDTIFINEKFIDSYNINIDDYNIEP
                     KAFIIRYKKDLNRFDVTGPISYSVNINTTVVGYGHIEKGNPVHLVQLLCQQINGSSIN
                     PDSKFGPDTYNQVKILQGRLGVTKDGVVGKATWQAAGERY"
     gene            complement(2256..3272)
                     /locus_tag="PC592_000432"
     CDS             complement(2256..3272)
                     /locus_tag="PC592_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF4054450.1"
                     /translation="MNYNDLLKSARENFNEKCKVCKICNGLACAGNVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTLLNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNCGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQLQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMTVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKAVKGKITILVDGGVRSGVDV
                     VKMLGLGADAVLMGRPFVIASFGGGLDGVEFFIEKVRSELCETMILTACQNVKDIDGR
                     VIWK"
     gene            complement(3602..3784)
                     /locus_tag="PC592_000433"
     CDS             complement(3602..3784)
                     /locus_tag="PC592_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054451.1"
                     /translation="MYKDESDECIHLMTAYIDSLSGYYSFIDTQLEDFMVKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4100..4519
                     /locus_tag="PC592_000434"
     CDS             4100..4519
                     /locus_tag="PC592_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HDF4054452.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYVFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIIQIENCIV"
     gene            4650..6491
                     /locus_tag="PC592_000435"
     CDS             4650..6491
                     /locus_tag="PC592_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4054453.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLNNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGVSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDINKANLYIDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIEA
                     LYIKIKKINDFNCKKMYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPMA
                     INNLAKSEVYLEKIKNQNLKEVAKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     IMKNIEEYTMYDLEIIYHQAKIYYIFGYYENALNTNKKLLEKSKNAKNYNYVKLAYKN
                     IYLCFEKIQDYEISMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYIDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITMIIKKYLKKDMLMIRYGGEEFLILSICKDYKKSKIFGRKLCRTVKKFLNNNL
                     TVSIGIDTCKNSSIDIREIIKNADKALYKAKESGRNRCLHYNDFKNF"
     gene            6533..8404
                     /locus_tag="PC592_000436"
     CDS             6533..8404
                     /locus_tag="PC592_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4054454.1"
                     /translation="MEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNTKLEDD
                     SRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDVYVISKIYIYLTLSAIS
                     IRKYDKANNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIDLVEEVSFF
                     KNLNNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLRLAQENNLYSIEAFCKCIIS
                     LCYLESGNNVEAIKYINNVLDVAHNNNSISVTERVSIKIDLIWAYLKEDMNKEAEVIL
                     LKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYESFGDV
                     FIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYGLIANG
                     YELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLVDDNKK
                     LENDILKDGLTKLYNRRYLEQQLNLFNGTRDKNMVAILVDIDCFKSYNDNYGHLAGDK
                     VIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESISVEEIDNIELYIKRVFKLLE
                     FEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEMLIEDADKNLYKSKKAGRNQYIII"
     gene            8412..10412
                     /locus_tag="PC592_000437"
     CDS             8412..10412
                     /locus_tag="PC592_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4054455.1"
                     /translation="MILLQKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEAVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEIDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRNFKTKQSLSNSEVDKFNSETTASAEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            10674..11933
                     /locus_tag="PC592_000438"
     CDS             10674..11933
                     /locus_tag="PC592_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF4054456.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKALGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINS"
     gene            11994..13781
                     /gene="iorA"
                     /locus_tag="PC592_000439"
     CDS             11994..13781
                     /gene="iorA"
                     /locus_tag="PC592_000439"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HDF4054457.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKDYVKNAKKMVTVPANAQIRRGVVEERMETLKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTSDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDNNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            13783..14358
                     /locus_tag="PC592_000440"
     CDS             13783..14358
                     /locus_tag="PC592_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HDF4054458.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELNRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            14411..15481
                     /gene="buk"
                     /locus_tag="PC592_000441"
     CDS             14411..15481
                     /gene="buk"
                     /locus_tag="PC592_000441"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF4054459.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDNGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGKYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGNVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            15697..16398
                     /locus_tag="PC592_000442"
     CDS             15697..16398
                     /locus_tag="PC592_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054460.1"
                     /translation="MGKMNLKSMARLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVIIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVLMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSD
                     EHKCKSSIVIKNEQN"
     gene            16458..16964
                     /locus_tag="PC592_000443"
     CDS             16458..16964
                     /locus_tag="PC592_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDF4054461.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEDGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEESLEGAIREAKEEIGIDITKDEMKIFRSMTH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLSE
                     IDNNKLNI"
     gene            17137..18159
                     /locus_tag="PC592_000444"
     CDS             17137..18159
                     /locus_tag="PC592_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF4054462.1"
                     /translation="MEDNKGLAHDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSYLNIPDSLIIIVLYALFAMLLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKKFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMRFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAIETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(18304..18612)
                     /locus_tag="PC592_000445"
     CDS             complement(18304..18612)
                     /locus_tag="PC592_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF4054463.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINEKNASCETFEMK
                     "
     gene            complement(18672..19100)
                     /locus_tag="PC592_000446"
     CDS             complement(18672..19100)
                     /locus_tag="PC592_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054464.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIKCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFTCSICGSTENVDVYHVNKNLGRETSKDVVVKCNKCICK"
     gene            complement(19321..20778)
                     /locus_tag="PC592_000447"
     CDS             complement(19321..20778)
                     /locus_tag="PC592_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF4054465.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGIIFLYYLCATLFPIDKIIGKIYPIFGAILLLSAAGVGVGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELIGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIVKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNM
                     NISYVLAAIFTVLYAILTVHSGRKLKSRADTKLAD"
     gene            21196..22110
                     /gene="nadA"
                     /locus_tag="PC592_000448"
     CDS             21196..22110
                     /gene="nadA"
                     /locus_tag="PC592_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDF4054466.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTILMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYITLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            22123..23424
                     /locus_tag="PC592_000449"
     CDS             22123..23424
                     /locus_tag="PC592_000449"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDF4054467.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMRAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFVDIPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            23405..24241
                     /gene="nadC"
                     /locus_tag="PC592_000450"
     CDS             23405..24241
                     /gene="nadC"
                     /locus_tag="PC592_000450"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDF4054468.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGNVGVELYKNDGDRVENREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSKYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGGVKNAVELARKNTSFVRKIEVEVETLDMVKEAIEAKADIIMLDNMSL
                     EMAKQAVDIINGRAIIEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            24499..24831
                     /locus_tag="PC592_000451"
     CDS             24499..24831
                     /locus_tag="PC592_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDF4054469.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPIGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            24993..25178
                     /locus_tag="PC592_000452"
     CDS             24993..25178
                     /locus_tag="PC592_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054470.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIVTKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            25206..26291
                     /locus_tag="PC592_000453"
     CDS             25206..26291
                     /locus_tag="PC592_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF4054471.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGSKVTIIYLISGFLVPFLVGFLGNCFGKEELSLHNDLEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAAIVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            26284..26742
                     /locus_tag="PC592_000454"
     CDS             26284..26742
                     /locus_tag="PC592_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054472.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            26771..27856
                     /locus_tag="PC592_000455"
     CDS             26771..27856
                     /locus_tag="PC592_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4054473.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKQKEEAKAGKDDYTITVG
                     YYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGAIP
                     KGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLPTD
                     PSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKANGK
                     EYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEVAL
                     RTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGADD
                     FDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            27861..28085
                     /locus_tag="PC592_000456"
     CDS             27861..28085
                     /locus_tag="PC592_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054474.1"
                     /translation="MENIKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            28095..28658
                     /locus_tag="PC592_000457"
     CDS             28095..28658
                     /locus_tag="PC592_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054475.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPKKMGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            28619..29248
                     /locus_tag="PC592_000458"
     CDS             28619..29248
                     /locus_tag="PC592_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4054476.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFIYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIIPASLPDILTGSRIAISTGWMSVI"
     gene            29288..29425
                     /locus_tag="PC592_000459"
     CDS             29288..29425
                     /locus_tag="PC592_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4054477.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            29425..30177
                     /locus_tag="PC592_000460"
     CDS             29425..30177
                     /locus_tag="PC592_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054478.1"
                     /translation="MKLSVRDINKTFVNNRVNTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSESGDVFINDKKVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEILLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            30190..30675
                     /locus_tag="PC592_000461"
     CDS             30190..30675
                     /locus_tag="PC592_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054479.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNMEKEYIESTLQYFIDKNIMVVDGDSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDVRINSICSVTGREIEIVIKNEKIEYVNNPSLRVLHINLDKYSNWAAN
                     C"
     gene            30682..30831
                     /locus_tag="PC592_000462"
     CDS             30682..30831
                     /locus_tag="PC592_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054480.1"
                     /translation="MNFFWTKSDFDAWTIEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKIIL"
     gene            complement(30963..31784)
                     /gene="yidA"
                     /locus_tag="PC592_000463"
     CDS             complement(30963..31784)
                     /gene="yidA"
                     /locus_tag="PC592_000463"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDF4054481.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNDIEVKYIQKDKIDESIKICKIMIVDEP
                     EKLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCANLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            32278..33972
                     /locus_tag="PC592_000464"
     CDS             32278..33972
                     /locus_tag="PC592_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDF4054482.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLGCVEDINNSHNYKEQQKNIHKLN
                     LLRNKIETLSNIALIRYSTDTLNKFYQEEKDYWDEYMPLYEELNSHFYNAIVNSKFKC
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKIRELANKAYYNFFEKNETKFDDIFDKLVKLRDKISKKLGFEDFVEL
                     GYIRMMRSDYREDMIKSVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFNFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSAIKFIPYGVIVDEFQHYIYKNPNIDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLDRGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DTGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      34304..34414
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            34518..34889
                     /locus_tag="PC592_000465"
     CDS             34518..34889
                     /locus_tag="PC592_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HDF4054483.1"
                     /translation="MIIITNNPKVKEEVQDREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVVLKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            34985..35932
                     /gene="trxB"
                     /locus_tag="PC592_000466"
     CDS             34985..35932
                     /gene="trxB"
                     /locus_tag="PC592_000466"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF4054484.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            36018..36335
                     /locus_tag="PC592_000467"
     CDS             36018..36335
                     /locus_tag="PC592_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HDF4054485.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            36602..37888
                     /locus_tag="PC592_000468"
     CDS             36602..37888
                     /locus_tag="PC592_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF4054486.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            38001..38474
                     /locus_tag="PC592_000469"
     CDS             38001..38474
                     /locus_tag="PC592_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:38133..38135,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HDF4054487.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            38506..39816
                     /gene="grdB"
                     /locus_tag="PC592_000470"
     CDS             38506..39816
                     /gene="grdB"
                     /locus_tag="PC592_000470"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:39553..39555,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF4054488.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            40063..41595
                     /locus_tag="PC592_000471"
     CDS             40063..41595
                     /locus_tag="PC592_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HDF4054489.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIVGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            41606..42751
                     /locus_tag="PC592_000472"
     CDS             41606..42751
                     /locus_tag="PC592_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HDF4054490.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFADIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            43057..44136
                     /locus_tag="PC592_000473"
     CDS             43057..44136
                     /locus_tag="PC592_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF4054491.1"
                     /translation="MSKVKKVVELLESKGIDALYLTKKTNVNYISGFPDEEAYAVICK
                     YGNFLVTDSRYMELAENVCEGFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYIKDEEEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGEASEKQLEIYNLVKEAQNVGVENMKVGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEDGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            44247..44846
                     /locus_tag="PC592_000474"
     CDS             44247..44846
                     /locus_tag="PC592_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054492.1"
                     /translation="MYKKHKFIKNIKQAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSVNFIKRPSRKYINTDVSSNFFIDNNLSKKSQE
                     SSQNNVMNVKNTIGFTSETDNYEKKIPTNNTEDFEDGETSELQIVIATVICVVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSRPD"
     gene            complement(45026..45898)
                     /locus_tag="PC592_000475"
     CDS             complement(45026..45898)
                     /locus_tag="PC592_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4054493.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISSYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTKNLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            46315..47718
                     /locus_tag="PC592_000476"
     CDS             46315..47718
                     /locus_tag="PC592_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054494.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISPDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASTKDKEEILKVVDPEGKLDVSTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVINFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            47745..49289
                     /locus_tag="PC592_000477"
     CDS             47745..49289
                     /locus_tag="PC592_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF4054495.1"
                     /translation="MNNEGTFEELSGRLRNKKLCDLIMNADEAAKFIKDGMVVGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEDGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGIVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            49320..50711
                     /locus_tag="PC592_000478"
     CDS             49320..50711
                     /locus_tag="PC592_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDF4054496.1"
                     /translation="MGKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKIAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKAQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            50904..52400
                     /gene="abfD"
                     /locus_tag="PC592_000479"
     CDS             50904..52400
                     /gene="abfD"
                     /locus_tag="PC592_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HDF4054497.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSTDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKTIAGIKKEEALNL"
     gene            52535..52810
                     /locus_tag="PC592_000480"
     CDS             52535..52810
                     /locus_tag="PC592_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054498.1"
                     /translation="MTCGVRFCGGCNPRYERGKALAIIKEHFNGRVDFSIAQENLEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            52834..54141
                     /locus_tag="PC592_000481"
     CDS             52834..54141
                     /locus_tag="PC592_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF4054499.1"
                     /translation="MSWRELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPTFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSDFDYIVEKSQPLYELEPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFVNNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAIEFEKRFKEKY"
     gene            54161..55279
                     /locus_tag="PC592_000482"
     CDS             54161..55279
                     /locus_tag="PC592_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF4054500.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVPPKKIKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     AQIDEFTDSTIANQQRLLANNYVELNREEIREIFANLY"
     gene            55564..56484
                     /locus_tag="PC592_000483"
     CDS             55564..56484
                     /locus_tag="PC592_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDF4054501.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLIIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPTRYEDVAYEVKEEEK
                     TDEDNEVDTIINKGMNYLTHIKEANKNIKSESMCDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            56599..57756
                     /locus_tag="PC592_000484"
     CDS             56599..57756
                     /locus_tag="PC592_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF4054502.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTSDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(57844..59343)
                     /locus_tag="PC592_000485"
     CDS             complement(57844..59343)
                     /locus_tag="PC592_000485"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDF4054503.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            59938..61362
                     /locus_tag="PC592_000486"
     CDS             59938..61362
                     /locus_tag="PC592_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDF4054504.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWIIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TIAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDNTSLEEAKAKVSDMKSVSKNSKKDIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDVLFKRLESK"
     gene            61396..63525
                     /locus_tag="PC592_000487"
     CDS             61396..63525
                     /locus_tag="PC592_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF4054505.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGMLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEESIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKTIEILSENRLLNLMDKCIIRK
                     VEGTLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMEIDFSMDIPLDEVGYITMHIRGAKQRSSSNHNALNLDDIEVMDITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYVYNGVE
                     KISRIIKDKLSINSIPESEIGYIAMHFASAIEKNLMMYANINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QLIKEKIKSIAQNKLINLNVKNGTKNKNKIYAQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCISERIDIMK
                     LSIIKLENRIILDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMILEVKDIVFNFYTNRLKAFIDK"
     gene            63555..63977
                     /locus_tag="PC592_000488"
     CDS             63555..63977
                     /locus_tag="PC592_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4054506.1"
                     /translation="MNKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            63996..65147
                     /locus_tag="PC592_000489"
     CDS             63996..65147
                     /locus_tag="PC592_000489"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF4054507.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVEAEIITTAVGPLVLTKIASTIAK
                     GIKNRKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYIGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFIYDIVKSAMVESGEGLIKKYNFDSEAHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYDLSVDNLILGIGAALHYN
                     NSEDAQSVELQELIKSNGVKKAVAKIANINNDEELLNNIEKSYIFMENL"
     regulatory      65253..65354
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            65537..66109
                     /locus_tag="PC592_000490"
     CDS             65537..66109
                     /locus_tag="PC592_000490"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDF4054508.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFEGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANNVRLESLAVVESIDNGTVKFR"
     gene            66173..66823
                     /gene="fsa"
                     /locus_tag="PC592_000491"
     CDS             66173..66823
                     /gene="fsa"
                     /locus_tag="PC592_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF4054509.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            66975..69899
                     /locus_tag="PC592_000492"
     CDS             66975..69899
                     /locus_tag="PC592_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4054510.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKS
                     GIKDKDLASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCENEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSQIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTIG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKDHIEKQIKEYDASIEVKPIAFLNNNLEDELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        27599 a         7586 c        12667 g        22264 t
ORIGIN      
        1 aaaaattcac atattgtaga attaaggtag caagagtttt gagggaggtg taaatgatga
       61 taagaaaaat accacaagca gaactaaaag taataaaatt catttggaga gtagataata
      121 cagtaacatc aaaagatgtt attgaggtta tggaacaaaa atatggctgg aaacaaacta
      181 ctacactgac acttttatct aggctggtaa aaagagggtt cttagatgct caaaaaatag
      241 ataaatatac aaattatgca ataatagtaa aacacaaaga ttatttaagt tttgagacaa
      301 aggatttcct aagtaatata catgatgatt ctttgaaaag tttaatttca gcattacatg
      361 atgatgaaaa tataggtaaa gataagctag attttttaga aagttatttt gataatttaa
      421 aagatgaata attatatgat atatgttttt gacaatctta taaagacaac tattgtatgt
      481 agtcttggta tttgtctatt attatttttg aaaagatatg tgtttaagaa gtttagtaag
      541 cgattcaatt attatatttg ggtagtaata gtctttagaa tgttactttt tctatttaat
      601 tatacagtaa tatatgaagt aaaagagccc aaagaaaata taataggaaa taatcttata
      661 cgaattgaca tttctataga taataatttt atgctgtatt tagcttattt atggttagtt
      721 gtaaccatag tcattgcagt ttatacattt gtaaagtata caagatttaa aaatcttgtt
      781 gttgatgtat cttatgatat tgaagataat gatgtaaact gtatctataa aaatttgttg
      841 aaaaaattaa atataaaaaa gaaaattgag ttaagaagtt ctgatgaatt gataagtcca
      901 gcggggatgg ggttatttaa atcgtacata tttttgccag attatcctta tagtaaagat
      961 gagctaaatt ggattttgaa acatgaatta atgcatttta aaaacaaaga tattttaata
     1021 aagtttttag ttttttctgt taaaacaata tattggttca atccacttgt ttatataatg
     1081 agtaataaag taaatctaga ttgtgaatta tgttgtgatg aaagtgtttt gatggattgt
     1141 tctttagaag ataagaaaga atatgcatta gcacttataa agtcaattaa acttagtaag
     1201 aattataata gtggtatttt gacgactgaa tttaataaaa caagtttgga aaagagactt
     1261 gacagtattg ttaagaaaaa aggtaaaagt ggaatattgg tgttattgat ttcgtttgca
     1321 ttattttcag ttacatattt taattttgaa agtattagtt ttgacaattc aaattcttta
     1381 aggaatatag gtattttaga aaaaacaggt gcagatctta aggaagaaga tgatattagt
     1441 gtgagagttg taaattaaca tatttttgca gtgttaaaag aacattataa tttattaaca
     1501 aattaggagg aattttgaaa tgaaaagtct aaagaaaatc ttaatagtca cagggtgctt
     1561 gactataata tctactagtt tagcatttgc aagtactaat aatgatgtaa atgtatcaaa
     1621 aagtaatgaa gatcaagcaa caaattcgtt tacaataact ggttatgaat ttacttatga
     1681 aaatgcacca caacctataa aatctgatta tgaaaaaaaa tgtaaagaat tgaatataaa
     1741 tccatctaaa aacgatacaa tctttattaa tgaaaaattt atagattcat ataatattaa
     1801 tatagatgat tataatattg aaccaaaagc atttattatt agatataaaa aagacttaaa
     1861 tcgttttgat gttactggac ctataagtta tagcgtaaat ataaatacta ctgtagtagg
     1921 gtatgggcat atagaaaaag gtaatcctgt gcatttagta caacttttat gtcaacaaat
     1981 aaatggttct agtattaatc cagatagtaa atttgggcct gatacatata atcaagtaaa
     2041 aatacttcaa ggaagattag gtgtaacaaa agatggtgtt gttggaaaag ctacttggca
     2101 agctgctgga gagcgttatt agaaaagagg ttgtcgcact aagaaatagg gcggcaacct
     2161 ttttatatag agtatattaa tcagtatctt ctaaaaatag ttgttattat atctaaagag
     2221 tctggaaata taagtgttat aaaactattt cacaatcact tccatataac tctaccatct
     2281 atatccttaa cattttgaca agcagtcaaa atcatagtct cacacaattc acttctaacc
     2341 ttctctataa aaaactccac accatcaaga ccaccaccaa aagaagcaat aacaaagggt
     2401 cttcccatca aaacagcatc agcacctaaa ccaagcatct taacgacatc aacaccactt
     2461 ctaacaccac catcaacaag tattgttatt tttcccttta cagctttagc tatatctggt
     2521 agtacctcac aagtaccagg ggtataatca agtactcttc cgccatgatt tgaaacaata
     2581 atagcactag caccagattc tacagtcatc aaagcatcat ctacagtcat aattcccttt
     2641 ataataaaag gcaatctagt agactcaacc aattctctaa tctcatcaat tgtcttagga
     2701 gaaaaaggat tttcttgaag ctgattattg ataagtccac aagcatcaag gtctacacca
     2761 actgcaaaag cacctgcttc ttcagacaat ctaatctttt ctattatctt tgaattattc
     2821 caaggcttta taaatacaat tccatttcca caattatctt ttaacacatc taaattatcc
     2881 agtaaaaaag tatctacatt ggtatcgcca accatagcat aaattccaga attagaacaa
     2941 cctctaacaa caggttctat gtattctttt tcagaaactt taccacccat gttcaataaa
     3001 gtacctgata caggggcagc gaatatagga gaactcattt ttctaccgaa taattctata
     3061 gatgtatctg gctttgaaac attatgtatt actctcatat ttatctttat tttttctaga
     3121 ctctttctat tttcaatgaa agatgaacca cttcctttac cacccatacc aggaacattt
     3181 ccagcacaag ccaatccatt acaaatttta catactttac atttctcatt aaagttctct
     3241 ctagctgatt ttagtaagtc attataattc atacaaaatc tctccttttt ataatattaa
     3301 aattaagcat tactatattg aaaatatctt agttgtaaat atagagatga tgttatgatg
     3361 agataaacta gataatacat attagatatt ttttattgtt gcagatagtt aaattatatc
     3421 atattagata gtaaaatttt gaaaaaaact aacttattta agtatacatt ttaaaaaaat
     3481 taaaaaagct atatatagat ttttaaagaa atctatatat agcttttaag tttatgacaa
     3541 tcttttttta ttaatgaata aataatatag aatacaatgt acaaaaaagc ttcttaaaat
     3601 gctaagataa tccccattta caaagcaaca tcattatact atgcaagttt gaatcaacaa
     3661 tgttttcacc atatttcacc ataaaatcct ctaattgtgt gtcaataaat gaataatatc
     3721 cacttagact atctatgtat gcagtcatta agtgtataca ttcatcactc tcatctttat
     3781 acatatatat ctccacctat atacaatata taaatttaga tactaaatcg tatcatatta
     3841 aatagttaag tatgtcacat ctatgtagtt atatatttat atccttatat taataactaa
     3901 agtgaatttt gacaatagat tttgggaaac tggatgttca aaatgtaaac ttggatttta
     3961 aaatgattaa ttaaaatagt gcatagtata tatgtataca taaattaatt aattataaag
     4021 attataaaca attactttta ttaactttat ttaagtggta gaataacttg gagattaata
     4081 attataagga ggatataata tgagtttata taagtttata tatgatgata aggaatattt
     4141 attaaaagag gagaattgta gtgctttaat aaatgatgaa gaaaatccag ttcaaggagt
     4201 aagtatttca aaaataattg atatacttaa tgaagcagaa gaagttgatt ttgatgtaga
     4261 atattatcaa gaagcatgtc cattatgttt agaaggggta aaggaaaaga aaaaattctt
     4321 tccttttttg gaatatcact tttatgtttt cagtaaagat ggagaatatg taataagtaa
     4381 tatatctgtt gattataaag gattatcttt taataaacta tcaagggcaa ataaagttga
     4441 taatagttat attgtaagtg tgataatttg tgaaaattgt caggattata taattcagat
     4501 agaaaattgt atagtttagt gtaaagtatg tcttaattta agagaaattt ctaaattgag
     4561 acatcgactt ttttcaaaaa tagtatggaa aattactaaa tttatgagat aatgtaagtc
     4621 ggaggtgagt tacaatatat agtaaatatt tggaagagat agatgataca attttagatt
     4681 caatgtttaa gctaaccttg aatgaaagat tattgaataa taacgatttt attgaaaata
     4741 aaattgatgt agtaaagaat ttaatcgatt gctataaaac cgaacaaaat agtttgatgt
     4801 tattaaaatc aaattttttg ctagctttat tatatggtat tcaaggggtt agtgaaaaaa
     4861 tgaaagagta tattttgatt tcctgtaaat atattgataa atgcttaccc aaagattata
     4921 agtttctagc acgattttat tcacaaatag ctattttaag tttaaaaaat gaagatataa
     4981 ataaggcaaa tttatatata gataaattta atcttatttg tgatgaaaat aattttctaa
     5041 ttgaagaaat tatttttaaa tcacaactta tttatattaa ggcaagtaag tgtatagaat
     5101 cttctgtaat aattaaagaa atagaagctt tgtatataaa aataaaaaaa attaacgatt
     5161 ttaactgtaa aaagatgtat ttttttatta ttggtaaaat atatttttta tttttagatg
     5221 atgctctaat tgctaaggtg aattttttaa aagcaagaaa atatgcagat ttactaaagg
     5281 atatgcaagt atcttcatta tgtaatataa agataggcga gtgtgaatgt tcatttgaaa
     5341 attatgaatg ttcgatggaa tatttcaatg aagtaataag caataaaaag tatagaaatg
     5401 taaatataat tcaaaaatat agagcatcaa acaatataac taaaatatta ataaagacta
     5461 gaaattatcc tatggcaata aataatttag caaaatccga agtatattta gaaaaaatta
     5521 aaaatcaaaa cttaaaagaa gtagcgaagt ttgatttatt tataagctta gctatgtatt
     5581 atgcaaaaag taatgaaaaa tcttttgaac aatcaatctg ctatttagat agagctaaaa
     5641 acatattaaa tataatgaaa aatatagaag aatatacaat gtatgattta gaaataattt
     5701 atcaccaggc aaagatatat tatatctttg gatattatga gaacgcttta aacacaaata
     5761 aaaaacttct tgaaaaatct aaaaatgcta aaaattataa ttacgtgaag ttagcatata
     5821 agaatatata tttgtgcttt gaaaagattc aagattatga aataagtatg aaatacttta
     5881 aaatgtatta tgagttaaaa atgatgtata taaaagctcg aaatagaaat tatatagatt
     5941 ctttaaatta tagacatgag tatatagaaa aagaaataaa taacatgaga aaagtaaaac
     6001 ttgatttaga taaaaaaaag tatattgacc atttaacaag tgcatataat agaacttttt
     6061 tgaacgattt tttagaaaaa caagaagtta gtgaatattg tacagcattt atgatagatg
     6121 tagattactt taaagaatac aatgatactt atggacacta taatggagat attgctctta
     6181 aaaatataac tatgataata aaaaaatatc taaaaaaaga catgcttatg ataaggtatg
     6241 gaggagaaga atttctgata ttgtctatat gtaaagatta taaaaaaagt aaaatatttg
     6301 gaagaaaatt atgtaggact gtaaagaaat ttttaaataa taatttgaca gttagtattg
     6361 gcattgatac atgtaaaaat agtagtatag atataagaga aataattaaa aatgctgata
     6421 aagctttata taaagcaaag gaaagtggta gaaatagatg tttgcattat aatgatttta
     6481 agaattttta actgttgaaa taggattggt gatttacttg aaaaggagtt taatggaaga
     6541 tttaaaaaga aatataaaca agatagaata cgatatgttg actaaattct atctaaattt
     6601 aacagactta aactacatct tggattatca caaagacctt ttaaatacaa aactagaaga
     6661 tgatagtaga gtatatactt tatatttaat tagtcttata aactatataa aaaaagatag
     6721 agaagcatca tacaactatt tgatagagtc attaaagtat attaagaaat tgtcattaaa
     6781 ggatgatgta tatgtaatat ctaaaattta tatttatctt actttatcag ctatttctat
     6841 aagaaaatat gataaggcaa ataattttta tttctcagca aaaaaaatta taagacaaaa
     6901 ccatttaaat gagttgttgg tcttgttaaa tatgagttta tgtgtagaaa taagtgcttt
     6961 atatcagacc aaaacggatg taatagattt agtagaagaa gtgtcttttt ttaaaaattt
     7021 aaataataaa gctcttgtaa gtagggcaaa ttatatattt gggagagttt atctatattt
     7081 atttaataac tttataaaaa gtatggagta cttaattgaa tgcctaagac tggctcaaga
     7141 aaataactta tactctatag aggctttttg taaatgtata ataagtttgt gttatttaga
     7201 gagtggaaat aatgtagaag ctataaaata tataaataat gtattagatg ttgcacacaa
     7261 taataactca atatcagtaa ctgaaagagt gtctataaag atagacctta tatgggccta
     7321 tttaaaagaa gatatgaata aagaagcaga agttattcta ttaaagacta taaaattaat
     7381 gaaagttgtt gaaggtgtat ataaggatta tttatattca tttatatttt tatattcagc
     7441 tgaaattgag ttgaagaaag ataattgtag ttttgaaaag gtaaatacct atttaatttt
     7501 atcaaaaaat atatatgaaa gttttggaga tgtttttata tataattcta aactagatta
     7561 catatataag ttgtatggag atttatatat aaaatttggc aatatagacg aaggtataag
     7621 ttgttatata aaaggtttaa atttagttaa aaagagttca ttaaatctta ggaaaatctc
     7681 tatattttat gggctgatag caaatggata tgagctaaaa aaagatttta aacttgcaat
     7741 agaatattat aaaagtatgg attggtattc tgatagatgg gaaaaaaata attcctataa
     7801 aacatctcaa gcaattcaca aacaatatga acttagacaa aaacaagaga gtttaagatt
     7861 attagtggat gataataaga aattagaaaa tgacatttta aaagatggac ttactaaact
     7921 atataataga aggtatttgg aacagcagtt gaatttattc aatggaacta gagataaaaa
     7981 tatggttgca atactggttg atatagattg ttttaaaagt tataatgata attacggtca
     8041 tctagcagga gataaagtta tagttaaggt aactgatatt ataagaagtg tatttataga
     8101 tattactgaa cacataatca gatatggggg agaagaaatt ctaatactag tagattctat
     8161 agaatcaata agtgttgaag agattgacaa catagaatta tatattaaaa gagttttcaa
     8221 actgcttgaa tttgagggta tcgaacatat atattctaaa ataaaaaact atataactat
     8281 aagtgctgga gtaagtataa aaagatgtcg tagtagaaaa gatgttgaga tgttaattga
     8341 agatgcagat aagaacctat ataaatcaaa aaaagcaggt agaaatcaat acattataat
     8401 ctaaaattga ggtgatttta ttgcaaaaaa aaataggaat tatagcctct gatattgaat
     8461 taaaagaaag aatagaagaa ttatatagag aagatgtaga aaatgggact ataataatcg
     8521 acatacttaa cctagactta atggaaaatc aaggtcgtat acttgttgaa aaaggtgctc
     8581 aagccataat tggtaggggt ggaggttata gtttagtaat agatacagta aatgtacctg
     8641 ttataccaat gaatatgaag tcaactgacc ttttaagagc aatagaaata gcaaagaaat
     8701 attctaaaaa agtagtatta attcttggag acaatgaagt ttcttttgac tatgttggct
     8761 ggagaaatgt cataagtact gaaataactg aagaatggtt tgaatctaag tatgagataa
     8821 gaagtaaagt tgtaaaatat atagaccaaa aagatgaagt tgtaatcgta ggtggaggtt
     8881 tggcatgttc ttttgcaagg caatatggaa ttgatagtgt atttgcaact gctagtgatg
     8941 aatctataag agaagctgta gaatattgta aaaagttgtt ggatacatta ggtgaagaaa
     9001 aatttaataa tgaagtgtta cgaaatatac ttgatggtat aaaagatgga gtaattgcta
     9061 tagatagtaa tggtagtata attttgtaca atgaaagcgc aaaaaatatg cttaaagtag
     9121 agagaaaatg tgcgcttaat aaatacattt tagatgtatt tcctaaaatg gagtggatgt
     9181 tagattgttt acatgaaaaa gaggctgtag aagatagaaa aataagaaat ataaataatt
     9241 taattgttaa tactagaacg acattgataa aagttgataa tagtacttat ggagttttag
     9301 gaataataca agatataacc aagctacaaa acttagaaag aaaaataaga tttgacttga
     9361 atcaaaaagg tctttatgct agatatactt ttgatgattt tttatttaaa gataaattaa
     9421 ctaaagaatt tattgaagaa gccaaaaaaa ttggaaaaag tgattataca actttacttt
     9481 atggagaaag tgggtcaggt aaagaaatta tagcccatag tatacacaat ataagtaaaa
     9541 gaaaagatag accctttgtt gccataaact gtgctactat agcagaaaat ttacttgaaa
     9601 gtgaactttt tggatacgaa gaaggtgcat ttactggtgc tagaaagggt ggaaaaagag
     9661 gattgtttga acttgctcat ggaggtactc tttttctaga tgaaataaat agtctatctt
     9721 ttaatattca gacaaaacta ctaagagtaa tagaggaacg tcaaataatg agaattggtt
     9781 ctgattatat aatacctcta gatataagga ttatagctgc aacgaatgaa tctttaaccg
     9841 aaaaaatagt tatgggtacc tttagggcag acttatttta tagattgagt agtttagaga
     9901 taaacatccc acctttaaga gacagaagag aagatataat acctttgttt aacaattttg
     9961 taaatgaagt attgaaggat gatggtctca atggaataaa cagtatagat gaaaattttg
    10021 ttttgactaa agatgaaatt gataagctat ataattatag ttggcctgga aatgtaagag
    10081 agttaaagac aatagctcaa aaatatgttg tgacaggtaa aattaaattg agacaagata
    10141 ggaattttaa aactaaacaa tcactttcta actctgaagt agacaaattt aattctgaaa
    10201 cgacagcaag tgcagaagtc caagatgagt ctataaatat aagtaaaata aatgatggta
    10261 agataagtat agatataaaa gaagtaaata agtatgttga agaaaaaata ataagtatgc
    10321 tttttgctca ggggctttct aaaaatgaag ttgcacaagt tcttggaata agtaggacat
    10381 ctttatggaa gaaatataat aaaaatattt aaatataatt acatataaat tattttgaag
    10441 taatgttaat ttttttaaac aagtgttaag aaaaattaac attatttttt tgcaaatttt
    10501 tattttttta gacaagcata tatatttata agaaaaatag ctaaaacact taatttaata
    10561 atgaaaaaaa taataattct aaacaaaatc agttttacat aaagtggaat ttattggcat
    10621 aataattgct taatatataa tgcaagagta aatacaattt taggggtgat ggtatgagtc
    10681 aaagtatggt tggtaagcat gcaatgtggc caaaagaaaa tgatgttata tttagcatat
    10741 ctggtagagc tcaagcagca gagaaggctc tcggtatgga taatgtaata aatgcaacaa
    10801 taggcgcgct aatggatgat tcaggaaaat taataacaat gaaaactgta tatgaagaat
    10861 ataaagcatt agataactgt gagataggtg catatgcagc tcttgaaggt caaccagatt
    10921 acttagaagc agttaaaaaa gtatttttca gagattactt accagaagga catataagag
    10981 tattagcttc accaggagga agtggtgcaa taaaattagc tgtatggaac tatactaatg
    11041 aaggagatga ggtattaaca tctgattggt tctggagtcc atatgtaagt atagctgaag
    11101 aggctaatag aaaagtagtt aattaccaac tttttgatga aaatagaagg tttaattttg
    11161 agtctttcaa agaaaaattt gtaaatatag cagaaaaaca aggtagagtt tttacaatta
    11221 taaacacacc agcacacaat ccaactggat atagtgtcgc agatgatgag tgggataaaa
    11281 tattagactt atcaaaagaa gttgcaaaag ataaagacaa aaagataata tttttcgtag
    11341 attcagcata tattgacttt gcaggtgatg atgatgtatg tagaaagttt tttaagaaat
    11401 tttctaattt gcctgaaaac gttctcgtat tggttggctt cagtatgtca aaaggattta
    11461 cagcttatgg tatgagaatg ggggctataa tttgtatatc ttcaagtgaa gatgtagctg
    11521 aagagttcca ttattcatgt gttcattcat gcagagcaaa ttggtcaaat tgtaatagaa
    11581 gtgccatggc agtattatct aacattgtaa atgaccctaa aaaattcaaa gaatatgagg
    11641 atgaaaaaga aatatacaaa aacatgctta ctagaagagc agatgtattt gtaaaagaag
    11701 ctgaaagagt aggattagaa attcttccat atatagcagg tttctttgta agtataccat
    11761 gtgataatcc aaaagaagta tgtgaagaat taactaaaca taatttattt gcagttccat
    11821 taaaaatggg attgagattt gcagtttgtg cagtttctga agataaatgt aagaaagcac
    11881 caagtattat aaaagaagca cttgaaagtt tagaagtaaa aataaatagt taatttcatt
    11941 gaacaaattg ggtggactat gaatttaata attgtagatg gagggaattt tatatgaaac
    12001 aattgatgac aggtaatgaa gcaattgcac gtggagccta tgaagctggt gttaaatatg
    12061 catctgcata tccagggact ccaagtacag aaatattaga aaatatagca acatataaag
    12121 atgcaatagt tgctgaatgg gctccaaacg aaaaagtagc acttgaggct gctatagggg
    12181 gttcaattgc aggagcgaga acaatggctt ctatgaaaca tgttggcttg aatgttgcag
    12241 ctgatccaat atttacttat gcatatacag gagtaaatgg tggtatggta cttattacag
    12301 cagatgaacc gggaatgcat tcatctcaaa atgagcaaga caataggatg tatgcaaaat
    12361 ttgcaaagat acctttattt gaaccatcaa ctagtcaaga agctaaagat atgataaaag
    12421 aagcttttga agttagtgaa aaatacgata caccagtttt atatagagtt acaacaagac
    12481 tctgtcattc aaagggatta gtggagtgct atgatagaga agaagttgaa attaaagatt
    12541 atgttaaaaa tgctaagaaa atggtaactg ttccagcaaa tgctcaaata agaagaggcg
    12601 ttgttgaaga aagaatggaa acacttaaaa aattctcaaa tgaaactgat ttaaactact
    12661 atgaaataaa tgatacaaaa ataggtgtta tagcttctgg tatgtgttgt aattttgcca
    12721 aagaagtctt tgggaaaaat gcatcatata tgaagctagg attcacaaat ccattacctt
    12781 atgaaaaaat aaaagaattt gcagagaaag ttgataaaat ctatgttata gaagaaaatg
    12841 acccatttat agaagaacaa ataaaagcat atggaataga ttgtattgga aaagatgtaa
    12901 taccaccata tggagaaatg acaccagatg ttttaagaaa agctatattt ggaaaaacaa
    12961 gtgatactat agaatacaaa tctgaattag taacaccaag accaccaagt ttctgtgcag
    13021 gatgtccaca tagaggattt ttctatgaac ttggaaagag aaaaaattta atagttggtg
    13081 gagatatagg ttgttatact cttggatttg ctcctccata taatggaata gattatgttg
    13141 tttgtatggg ttctgctttt ggaactgcac atggagctca aaaagttctt aatatgaagg
    13201 ataataatga aaaaagatta gtaggtgtac ttggcgattc aacattcttc catacaggaa
    13261 taaatgggct tttagatgtt gtttacaata gaggaaattc tatttcagtt atattagata
    13321 atagaataac tggaatgaca ggtcaccaag aaaatccagg ttcaggatat actttacaag
    13381 gtgctaaaac taaagaagtt gatatagaag gattagttaa agcttgtgga atagaacatg
    13441 taagagttat aaaccctaat aatttaaaag aagtaaatga agcgctagat tgggctttag
    13501 ctatagaaga tgaaccatca gtaataataa caagatggcc atgtgtactt aaaaaattct
    13561 ctaaagagga tatagaggaa tttaataatc catttaagac taagtgtaaa gttgaccatg
    13621 ataaatgtat aggatgtaaa ttatgtttga aaactggatg tccagcacta tcatttgata
    13681 aagagaataa gttatcaaat atagatagaa accagtgtgt aggatgtgga gtatgtgcac
    13741 aagtttgtcc aaaacaagca atagttaagg aggaaaaata atatgactaa gagtatactt
    13801 ttggtaggtg taggaggtca aggaactata cttgctagta aattattaac tatgggattg
    13861 atggaagctg gatacgatgt aaaaatgagt gaaatacatg gaatgagtca aagaggaggt
    13921 tcagtttcct cacaagttag atatggagat tgtgttcatt ctccagttat agaaattggt
    13981 ggagcagata tattagtatc ttttgaaaaa atggaagctt taagatggtt caattatcta
    14041 aaaccagaag gaaaagcttt agtaaataat cataggatag attctatgac tgttttaatc
    14101 ggaggagctg agtatcaaga aagtgatata gatgcggagt taaatagatt aaatgcaaaa
    14161 gttataaatg cagctgataa agctgaagaa ctaggaaatt caaaaataat gaatgttatt
    14221 ttattaggat gtctagttaa atctatgcaa ttagagtcta ttgactggga aaaaattata
    14281 agtgaaaatg ttaagccaaa atttgttgaa ttaaacataa aagctttcca tgaaggtatg
    14341 gaaatggtta gcaaatagtt tataatagat ataaatagac tatagaaatt aaggtgaaag
    14401 gaagaaaatt atgacttaca gaatattagc cataaatcca ggttctactt ctacaaaaat
    14461 agcagtatat gatggagaag aacaaattct tgtgaagacg atagaccatc cagctgaaga
    14521 gattgcaaaa tataatacta tacaagacca gtttgaaatg cgtaaggaag cagttttgaa
    14581 tattcttaaa gaaaatagta tagatttaaa atctcttagt gcaatagtag gaagaggtgg
    14641 agttttacca ccagtaaaat caggagcata tttagtaaat gaagaaatga ttgatgtact
    14701 tagacataga ccagtgcttg aacacgcttc caacttaggt gctgttgtag cacatgcaat
    14761 atcagaacct cttggaataa attcatatat ttatgattct gttgcagtag atgagcttat
    14821 agatgtagcg agaatatctg ggctttgtgg aatggataga tcaagtgcag ggcatgcatt
    14881 aaatactaga gcaatggctt taaaatatgc taaggataat ggaaaagatt ataagagctt
    14941 aaatttaata gtagctcata ttggtggagg agtaagtatt tatcttcatg aaaaaggaag
    15001 aatggttgat atgttatctg atgatgaagg accattttct ccagaaaggt caggaagagt
    15061 acctgccaca aaattagtgg ctgcctgtta ttcaggtaaa tactcagaaa gagaaatgac
    15121 taaaaagata agaggtaaag gtggtatagt ttcataccta aatactgtag atgctagaga
    15181 agttgaaaaa atgatagcag aaggaaatga agaagcaaaa attatttatg aagcaatggc
    15241 ttatcagtta gcaaaaggta ttggagagtt agcaactgta gtagatggaa atgtagatgc
    15301 tataattata acaggtggaa ttgcatattc tgaaatgttt acttcaatgg ttaaaaagaa
    15361 agttgagttt atagcacctg tagaaattat ggcgggagaa aatgagttgg aatcacttgc
    15421 ttttggaact ttaagagtac taaatggaga agaagaagct agaatttata gtgaaaatta
    15481 ataagaaaaa ctaaaaatgt ttatatacta aaaaagtggt atatccgttt tttatacacg
    15541 aaagcttaga gtataggtga aaatgtataa agtttggatt gccacttttt ataattaaaa
    15601 ttttatctta agctaataaa taattctgta aaatttcgta tttatatata ttttattggt
    15661 atttattgtt attattatta tgaggagtga tttttgatgg gaaaaatgaa tttaaaaagt
    15721 atggcaagat tattttcagg tttttttata tttgcaattt cttctgtgct tatgattaat
    15781 gcacatgtag gtcttatgcc ttgggatgta cttcatcaag gtttatctat aaagctaggt
    15841 ataactatag gtcaggcttc tataatggta ggagtcataa ttgttatatt ggatgcagtt
    15901 tttggtgaaa atataggatg gggtacttta ctcaacatga cgtttatagg aatttttatt
    15961 gatttagtaa tattttctgg agtgatacct catgcaagta acacttatat aggtgtgctt
    16021 atggttgtta taggaattat tttggcagct atagcaagct ttctatattt aggtgtttgt
    16081 ctaggaagtg gaccgagaga tgggcttatg attgctcttc agaaaaaaac taataaatct
    16141 gtacgtcttg ttagaacaat tcttgaaata ctagcattgg ttgttggttg gttattagga
    16201 ggttctgtag gtattggtac tcttgtaagt gctttaggtt taggatatgt attacaaata
    16261 gtgtttagaa tatttaaatt tgatacaaaa ttactaaaac atagatttat tatagatgat
    16321 ataagagaat ggaaggaaaa gaaaagtgat gaacataaat gtaaatcaag tattgtaata
    16381 aaaaatgagc agaattaatt atgctaaaat atatttatag tttatcaaag ttatagtaaa
    16441 ggcaaggaga ctttgaaatg gaattatggg atttatataa tgctgatgga attaaaacag
    16501 gaaatgttat aaaaagaggt aattctattg aagatggtta ttaccatttg gcagttgaag
    16561 tgtggatttt aaatagtaac tctcaaattt taattcagaa aaggtctaaa agtaaaaaga
    16621 cattgccaaa tatgtgggga atgacaacgg ggtgtattgt ttctggggaa gagagtttag
    16681 aaggagcaat tcgtgaagca aaggaagaaa tagggataga tataactaaa gatgagatga
    16741 agatttttag aagtatgact catgaagata ccctttggga tgtatatttg gtgaaaaagg
    16801 aatatgatat atccaaagcc attttacagg aggaagaagt aagtgatata aagtgggtaa
    16861 gcacagatga aataagacaa ttactaaaag aaggtttatt ttttgaatat ccagagatat
    16921 acgaattgct atctgagata gataataata aattaaatat atgatgtaga gcagatttca
    16981 gtataagtat gattaaaaat ttatcttctc taaattttaa tattgtttta tgaaaattaa
    17041 taagttattt ttagtatttt tctacttgtt ttttaagatt aaaataaaaa agggcggtca
    17101 ttgtaaagtc ataaaaattt ggggaggctt taaactatgg aagataacaa aggattggca
    17161 cacgacagtt caaagtataa aattgtttct atatctgttg tagtaattat tctaattaca
    17221 ttttggtata tgttaaatat ggtgctttta acattcatta tgacttttat tttctataac
    17281 ttgcttgtag ccacaagaaa acgaattaag aaattttctt atttaaatat tccagattca
    17341 ttgataatta tagtgttata tgcactattt gccatgttgt tggtattaat tagttatgca
    17401 gttgtaccaa taattatagt tcaacttaca gagttgagta gggtttttag tgattttgat
    17461 gtaaatcaat ttgctcaatc tttaggacca aaactgtatc ctattgtttc aaagctagat
    17521 tttaataaat atatttcaca agcagggcta ctcatagcat caacagcgac aaaagttgga
    17581 agttttggag taaatatatt attagctttt ttgttgagtt tacttctttt acttgaaaaa
    17641 aatgaaatta aaaagtttgg agataaactt tctgatagta agatttcttt tatttataat
    17701 tcgcttgtat tttttggaaa gagttttgtt aaaaattttg gtgaagtaat gaaagtgcaa
    17761 gtgatgattg cctttataaa ttctgttgtt tctatgattt ttttaggttt catgagattc
    17821 cctcaaatat gggccttagg atttatgatt tttgtgttag gtcttattcc agtagcagga
    17881 gttattgtgt ctttgattcc attaactgta atagcattta atacaggagg aataacaaag
    17941 gtttttggag ttttacttat gatttgtata gtgcatgcaa tagaaacata catattgaac
    18001 cctaagttga tgtcaaatag aactaaactt ccagtttgtt ttgtttttat cattttactt
    18061 gtaggagaac actacttagg tgtatgggga ttactaattg gagttccaat atttatgttt
    18121 cttatggata ttctaggtgt taaatttact tctagataat atattaaaat aataatttat
    18181 ttttatatat attatgaatt gttttaaaaa agaacctata aatagacatc attaataaag
    18241 atatctattt gataggttca attttgattt ttataaatac tataaactta aatgaaaaga
    18301 aatttatttc atttcaaaag tttcacaact tgcatttttt tcatttatat gaactttttc
    18361 agctttgcaa agttcatttt tattgtattt acattttaca gcttcacaat gaatgttatc
    18421 tgtatcaact tggttagttt cattagaacg actagttatt ccagatgtat atttgtcttc
    18481 aaaagaagca caataagtat tttctgtagt agttgcttgc attccatcta cttttatact
    18541 accagcataa cagtatccac tagtattata agcacaatta gtagcagcac aatttaaatt
    18601 attatttttc ataaataacc tcctaagttt tatttaaact tattatgtga agttatctaa
    18661 attttataca cttatttaca aatacattta ttacatttaa caactacatc tttggaagtt
    18721 tctcttccta aatttttatt aacatgatat acatcaacgt tttcagttga accacatata
    18781 gaacatgtaa aattattttc tagtagagtt ctttctttaa ataacttcca atacatagaa
    18841 ttgatgtaat cattataatt taccttgagg catgtctcaa ggaagtttat gtatagattg
    18901 tctaaatctc ctgtatttaa ctctgtatat tctggttcaa aatattcaca acatcctcta
    18961 aaatcaggct ttgtatctga aataacacat ttaatatcat atctatagtc taggctaggc
    19021 cccttaaatg aaagatgtgt gcaaaaagaa caagatgttt ctggtagatt tttttcaagt
    19081 tcatgtaatt tattattcat aagtattcct ccaaaaaatt tattttaagt ataaatgaat
    19141 agattatttt aaaactttta tttatttata ttagaaatat aggataaata ttccaataag
    19201 gagtaaatac ttaaatgttt atttctgtat taaataaaaa agaggcaaat ctaacttgag
    19261 attgcctact tttttattac tttttaataa aatttaatct aaatattatt ttatttacct
    19321 ttagtcagct aatttagtat ctgctctgct ttttaacttt ctaccagagt gtacagttaa
    19381 aatagcatat aatacagtaa atatggcagc taaaacgtat gatatattca tgtttaagtt
    19441 aaatccaatt tgagcattaa atatataact aaatataaca aaagaataaa acatacctgg
    19501 aattaagctt ataatataat tcttttcttt tactataagg taaactgtaa tcattgcaaa
    19561 cgcaaatatg gcgatagttt gattactcca agagaagtat ctccacaata tattaaatcc
    19621 agaggcacta agttttgcaa atataagaat ggctatgaca ggaataaata tacagattga
    19681 taatataaca cgatgtttct tttccttttg gtcataatga aagtaatctg caagcattaa
    19741 tcttaaagat cttaaagctg tatctccaga agttattggt aaaacaatta cacctattat
    19801 agctatgata ccaccaatag agccaagtaa atctcttgca actaaaccta ttacatcagg
    19861 agaacctatt aattccttag gtattccttt attgtagata cccatagcag cagcagccca
    19921 aatcattgca attagacctt ctaaaatcat catattataa aaagtagtct ttccttcttt
    19981 ttcatttgaa actgatcttg ctataagagt agcttgagtt gagtggaatc cagaaacgat
    20041 accacaagca actgtaacaa agaatgtagg aataagagga atcccatcag gatgaatacc
    20101 tttccaattt gcaagactta aattagccaa atcataacct tgtgtaaaga ttccaactcc
    20161 aacaccagca gcagataaaa gtaggatagc tccaaatatt ggatatatct ttcctatgat
    20221 tttatcaatt gggaatagtg ttgcacataa gtaatataga aagataattc catagactat
    20281 ccagacaact ggattattta tagtcgattt catatttaaa atttgagtaa caactaaatc
    20341 tccaggtgta taaataaaaa ctgcaccgac taaaagcatt aaaagacaaa ggaatatatt
    20401 atagacttga aatactttat tacctaaaaa tctacttata agagaaggca tttgtgctcc
    20461 tttttctctt atactaatca ttccactcat atagtcatgt aaagctcctc caaatacaca
    20521 gccaataggt attagtatga atgctattgg accaaacaat ataccttgta taggtcctag
    20581 aattggtcct gtaccagcta tattaagcaa ctcaattaga ctatttttcc attttttcat
    20641 tggaacatag tctactccat cactttgagc aagtgcaggt gtttttctgt catctgggcc
    20701 aaatactttt tcacaataag caccgtataa agcacctcct attagtaata tagccaagcc
    20761 gattaagaat gttgtcataa tatcacccca tttataaaat tttttggtct ttgtatacat
    20821 attatctaaa tgtgtagatt tatatgacat ttaattctgg acaacctaca aattctataa
    20881 agtattaaaa ctaatataat ttcagaaata aatacatata cataaccatg tacttagtat
    20941 acaggtattt gatattattt tcaatattat atcaataaag aatataaaca aaattctgat
    21001 aatattttac aaaaaaatta aaaaatataa aaaatagttt aaatagatga ggaaaaaagg
    21061 aaaatgaatt gatactgtaa atgtctatat cttaacaata ttaagaggtt taaaattctt
    21121 gaagaaagaa tagtcaagtg atataatgag tttacaggtg tatatacact agtacatata
    21181 gaaagcggtg caattatgga taaagattta acatatcaaa tcaaagagct aaagaaagaa
    21241 aaaaatgcaa taatacttgc ccatttttat caaccaccag agatacaaga attagcagat
    21301 gcagttggtg attcatatta tttaagtgag attgctagag attgtaaaga agaagtggtt
    21361 gtattttgtg gagtaaggtt tatgggagaa agtgctaaga tattatcacc tgaaaaaact
    21421 atattgatgc cagtaagtaa tgctgggtgt gctatggcag atatggtaga tgaagaaggc
    21481 gtgataaaat taaaacaaca gtatccaaat gctttggttg tatgttatat aaactctaca
    21541 gctaaagtta aggcacattg tgatgtttct gttacatctt ctagtgcaat taaaatatta
    21601 gaaaacatag ataataaaga aattatattc cttccagata aaaatttagg aggatatatt
    21661 gcagaacaat ttccagataa aaactttata ttttgggacg gatattgtaa ataccacaac
    21721 aatataaggg ctgaagaaat aattgagtta aaagataagt ataaaaatgc agaagtatta
    21781 gtacatccag aatgtaaaaa agaaataaga gatttaggag attatgtagg tagtacatca
    21841 ggaataataa aatatgctac taatagtaaa aacaaagact ttataatagc aactgaagaa
    21901 ggtatattac atgaattaaa gaaaaataat cctaataaaa atttttatat ccctggtgga
    21961 aaaatactat gtacagatat gaaaaagaca acattagaaa atttatatat tacacttaaa
    22021 aatatggaaa atgaagttat tgtagaagat gaaattatgg aaaaggcttt aaattcactg
    22081 cttaacatgc acaaattagc agaaggatag aggtatagac ttatgaattt agaacaagat
    22141 gttttaatag ttggaagtgg agtttcagga ttatattgtg cattaaattt agataaaagt
    22201 ttaaatgttc tagtagtatc aaaatcaaca attgaaaaca ataatacata tcttgcacaa
    22261 ggtggaattt caactgctag aaatattgat gatatagaat cctttgtaga agatacaatg
    22321 agggctgggc agtataaaaa tagagttgaa gcagttcaag tacttgcaga tgaatctata
    22381 gaaaatgtag ggcagatagt agaatatggt atgcctttag ataaagaaaa tggagagata
    22441 gattacacaa gagaaggagc tcatagtgta aatcgaatag ttcatagtaa ggataatact
    22501 ggagaagttg tttttaaaac tttattaaaa gaagctaaaa ctagagaaaa tataactctt
    22561 atagaagatg cttatctttt agatatacta aaagatggta ataaatgtat aggggctaga
    22621 atttttaaat ctaaaaaaga gattcatgtt ttttcaaaaa tagtagtttt agctacaggt
    22681 ggaattggtg gactttttaa aaattctact aatcaaagac atcttacagg tgatggaatt
    22741 gcaatagctt taagaaataa tataaaaata gaaaatttag aatatattca aatacatcct
    22801 acagcttttt atgaagaaaa taatgaaggt aggagaatgc ttatatctga atcattaagg
    22861 ggagagggag ctaagctttt aaataaaaat aaagaaagat ttgttgatga acttcttcct
    22921 agagatgtag tttcaaaagc tatttttgaa caaatggaaa aagataagtt accttatgtg
    22981 tatttagatg caacacatct agatagtgag tatttaatta atagattttc ttttatatat
    23041 aatgaatgct tagctagagg aacagatata acgaaagaat gtataaaggt atctcctgca
    23101 caacattatt ttatgggcgg tatacatgta gatttggatt caaaaacatc tatggaaaat
    23161 ttgtatgcag ttggtgaaat tagttgtaca ggtgttcatg gagccaatag attggcaagt
    23221 aattcattac ttgaagggct tgtattttca aaaagggcag ctaaaaatat aaactcggtt
    23281 atagataatg taaaagttaa gtttgtagat ataccagata tggatataga tatagaacag
    23341 gtaaaaaaag aaaataaaat attagtcata aaagaaattg aaagaacaag tgaggatttt
    23401 ggtgatgaat tatttgatta ttgatagaat gatacaagat gctttgatag aagatgttcc
    23461 aagtgaagat ataacaacaa attctattgt agatgaaaac tctaaatcta ctgtagattt
    23521 aatttgtaaa caagatggta taatagctgg cttaggtgta tttaagagag tttttgagat
    23581 acttggtaat gtaggtgtag aattatataa aaatgatggt gatagagtag agaatcgtga
    23641 aaagatagct gtattaacag gtagtactag aaatttactt gtaggagagc gtgtagcatt
    23701 gaattattta cagagaatga gtggcatagc tactattaca agtaagtatg ttgaaaagct
    23761 tgaaggtaca aatacaaaat tattagatag tagaaaaacg atacctaatc ttagaatatt
    23821 agataagtat tctgttaaag taggtggggg atgtaatcac agatttaatt tatctgatgg
    23881 aatattgctt aaagataacc acattggggc tgctggtggt gttaagaatg cagttgaatt
    23941 agctagaaaa aacacttctt ttgttagaaa gatagaagta gaagtagaga ctttagacat
    24001 ggtaaaagaa gcaatagaag ctaaggcaga tataataatg ttggataata tgagtttgga
    24061 aatggcaaaa caagcagtag atattataaa tggaagagca attatagaat tttctggaaa
    24121 tgtaaattta gataccatag aagatatagg aaaaatcggt gtggatgttg tttctgtagg
    24181 agcacttaca cattctgtta aagctctcga tataagtatg aagaatttga gaaatatata
    24241 aattttatat tgaaataaat ttaattgaaa tagactcctt aaatttgatt tataaattta
    24301 aggagtctat tttttattca ttaaaattaa taaaaatata aaaaaatcaa tcaataattt
    24361 aataaaaata gataaacact atatacactt ttaataatat agttattatc tattttacag
    24421 ataaataaga ataaacttat aatataattg tatctgtaaa attttgtaaa aatataaaaa
    24481 gtataggggg gaataaaaat gaaagtagct tatattttta gtagtactaa tacacacaaa
    24541 attctagaca aaatgataat accacaactt gaacaaggaa ctcatggagt agatgttcta
    24601 gggatgtttt tctttatgga taatacccta tttttatcta aaggtaatcc tataggggag
    24661 agattaagta aattacatga aaaaactgat atgataataa tggcttgtga ccaatgtgct
    24721 atagaaagag gtatagagaa taatttggtt gatggagcta caattggatg tttcccaaac
    24781 ctatatgctt gtttaggcag tgcaggtgtg gaccaagtta taacgttata aattagtgta
    24841 ggatacaatc catagaaaaa tttattttct gtggattatt ttaagtaaaa gataaattgt
    24901 ttaaagtagg ggatgagcaa atgtctaaaa ttttagttga atttataaac acttgaccat
    24961 cttgtgatga gcatggagtg tttataaaaa aaatgtcaga aaagtatgct gataaattgg
    25021 aaataaaatt atatcaagca ggcaaagatt tttcatatat aaaaaaatat gggattgtaa
    25081 caaaaggaac tttaataata aatcagaaaa agaaatatga tagattaaat aaagacacaa
    25141 ttgaaagggc aatagtagaa gctataaaca ataattaaaa gtttaaaaat taggagtatc
    25201 aaaaaatgaa tatattagaa attgttttaa atggagttaa agatactata gtagcttcca
    25261 tagttacatt aaatggagca tcaggatggc ttatgataag ttttatatta gcaggagtgc
    25321 ttcacaatgt tttaactcct agaagatttc aaaaacaact tggaaataag aaattttcct
    25381 ctttgattaa aagtactatc tcaggaatgt ttttaccaat atgtagttgt ggggtaatac
    25441 cacttggaat aagcatgtat tattcagggg catatttagg accggtactt gcttttatga
    25501 catcaactcc aataataaat ccaatagctg tagttctttg tctgggtctt ttagggtcca
    25561 aagttacaat tatttatcta atatctggtt ttttagtacc atttttagta ggatttttag
    25621 gaaattgttt tggaaaagaa gaattatcac ttcataatga tttagaggaa gaagtaatag
    25681 aattagaaga agaaaaaaga agttttatgg aaaatatgat tgatggtctt aaatggtctt
    25741 tcggggagtt ggctcttact attagtaaat atgtagtaat gggtatggtt tttgcaggat
    25801 ttataacaac catttttcca aatagtataa ttcaaaaata tttaggaaat ccaggtttgt
    25861 tatctcttgg aagtatagca atacttgcat gtgttatgta tgtatgtgct gtaggacata
    25921 taccgtttat agcagccatt gttgcaagtg gagcatctcc tgggatagct ataacatttc
    25981 taatagctgg agcagctaca aatctaccag aacttataag tatgtttaaa cttattggaa
    26041 aaagaactgt tattatatat tctgtaactt tgacactgtc ttcaataata attggatata
    26101 taacaaattt acttttagtg aacaataact cagtaaattt agatgcaaca aattcttcaa
    26161 tacagttggc aaataaacta atgttaaata tacctgatag ttttgagtat gtatgtacga
    26221 ttttaattat tttatttgca tttaaatcaa taataccaaa gatgaaagag gtcataggaa
    26281 atcatgctta aaaagatagt tataatatcc tgtatagtag ttgtgttaat cattttatca
    26341 aaaatagttg atgataacat caaagaagat gcctctattc caaatgtgaa taaagaaaca
    26401 ttagaatatt ttagaaaaaa ttataaagaa gacataataa cttgtgctga agaagactta
    26461 aataatgatg ggaaaaaaga tttagtagtt atatataaaa aaagcaataa ttcaaatgaa
    26521 atggtagttg tggtttctga taaaaatagc cattatataa caaagccaat accagcacct
    26581 atagagaatc aaactataac ctttaaaaat attgatgata aagcaccaat agaagtaata
    26641 gtatcagggt ctaaaaatgg taatgtagga tatgctattt acagagtaga gggtaagaaa
    26701 tttgttgatt tatttggcga agatatggac aaatgttgct aaaaataata cataaaggtg
    26761 ggaaatttat atgaaattat ctaagaagat tcaagcatta atcttatttg gtgtaatggg
    26821 tacatctata ttaacaggat gtagtagtaa acaaaaagaa gaagcaaaag ctggaaagga
    26881 tgattataca ataacagtag gttattataa ttgtgaccat atgactgcgg gaccagtagc
    26941 agaatcagca ggaatatata aagatttagg tcttaatgta aaaactgttg gaaatggtaa
    27001 agttcctgaa gctatggcag caggaaaaat ggatgcaggt tacataggaa ctaaaggttt
    27061 agttggagca atacctaagg gttcaccaat aacaatagca gctaacaacc atactggtgg
    27121 ttctgaatat ttaatagttt caaaagatat aaaagaacct aaagatttaa ttggtaaaaa
    27181 aattgcaaca gatatgagtg atttcttatg gacaagtgat tatggtccag aaacaggttt
    27241 accaactgac ccatcaaaat atgaagttgt aaatatggat tcagacaaag ataaatattt
    27301 agctcttaaa actgggaaaa ttcaagcttt tacatcttgt gacccttggg gttctgtagc
    27361 tgaaaatgac ggtgcaggaa aaataatagc atctactcaa tataaagaaa aagctaatgg
    27421 caaagaatat aactgttgtt cattctcatt gaacaaaaac tttataaaag aacatccaga
    27481 tttagcaaaa aaattggttc tagcacatac aaaagcaata gaatatatat atacaaatcc
    27541 agctgaagca gctaaaatat ttgcaaaata ttataatgta gaagaagaag ttgcacttag
    27601 aactatctat aagaagactg ttggagaagg tagaactctt acttggaaag ttacaggtga
    27661 agaatataaa aacaatttac aaatgtataa agatttaaag gctttagatg atatacctaa
    27721 atatgaagat acgattgata caagcttatt agactcttgt ggagctgatg attttgacaa
    27781 atttataaaa gaaaaagtta acccagagtt tcctgaaggt atgagttatg aagattggaa
    27841 agcaaaggta ttataaataa atggagaata taaaaaatat aataatactt tttatcatta
    27901 ttttaggaag tatatttata atatttttta attttgaaga taaagaagaa ataaaaggaa
    27961 aactaagaat aggggtatct gatgatacct ctggttttgt aataaattat atggtaaata
    28021 gagactactt tgaaaatata aaagtaagtg atataatgga tatttttaca attaatgatt
    28081 gctgagcaag tacaatgcag tgggctctga gttcagagga aatagatata gcaatcatat
    28141 gtaaagatgc tgcaaaacaa tatgtaaatg taaatagtgg atttgaaatt gttggtactg
    28201 tagttcaaaa ttctgatata tttctattaa gtgataataa tcctaaaaag atgggagtca
    28261 ttcaaaatag agattaccag tcagaattgg ttaaaaaata ctacaagaat gtggaagtag
    28321 ctcccttatt agggactgca cttgcatatg gattagaaag taatttagta gacggtgttg
    28381 taatagattg cataaagtca attgggttag agggtaaaag aaaatctaca actaaattag
    28441 gagattatga tacctatgta ttagttgtaa gtaaagagtt taaaaaaagt aaagcatata
    28501 gtgattttat aacactttac aataaaagtg ttgatgcttt aaagaataaa gctacattta
    28561 agaaagcatt aaaagagtac aggaatataa gaaatataga tatggaggaa ataagcaatt
    28621 ggaaattaaa atttctaaag ataaaagcga tagattaact aagaaaaaaa ctgatggtag
    28681 tatggatatt ttatataaaa taatactatt agttattata tttttagtct ggcattttgc
    28741 agcaaaagat atagggagtt ctttattact tccaatgcca gtagatgtaa taaaaggttt
    28801 ctttttctgt gtgacagatg cagagacagt tactaatctt tttataacat tgcagagagt
    28861 acttaaaggt tttatctatg cattattgtt tgggcttcca ataggattta ttatgggatt
    28921 ttctaaaacc tttgaaaggg ttttatctcc agtagtagat tctgtaagac aagttccaat
    28981 aatggcatgg gttcctctta ctatagtgtg gtttggtata ggagatggtc caacaatatt
    29041 tttaatagct ttttcagggg tcttccctat aattttaaat actattcaag gagtaagagc
    29101 aatatcaaag gattattata atgcagctag aagtatggga gcatcaccaa ttgtgatatt
    29161 tacaaatgta attattccag catctcttcc agatatacta actggttcaa gaattgctat
    29221 aagtacagga tggatgtctg ttatctgagc cgagtttata gctacgagtg ccggtctcgg
    29281 ttactcaatg gtacaagctc aaacattaat gcatacagat gtattaattg ggcttatgat
    29341 atttgcagct ttaatagggt ttataataga tagggtatta aagtttataa ataaaatcct
    29401 ttgtagatgg aggtttgcag attaatgaag ttaagtgtaa gagatataaa taagacattt
    29461 gtaaataata gagtaaatac aaaagtttta gaagatataa gtatggatat agatgatgga
    29521 caatttgtct gtcttttagg accatcaggt tgtggaaaaa caactttact tactataata
    29581 ggtggatttc aaaaatcaga aagtggagat gtttttataa atgataaaaa agttaaaaaa
    29641 ccaggaatag atagagcttt tatatttcaa aattatgctt tatttccttg gaaaactata
    29701 agaggcaatg ttctatttcc tatgaaacag cagaaaatac caaaagaaaa aagagaagaa
    29761 atgctagaag aacttttggt tatgtcagac ttgaaaggaa aggaaaaact gtttccacat
    29821 caattatctg gaggaatgaa acaaagagtg gccatgataa gagctttagc atgtaatcca
    29881 gagatattac taatggatga accattaggg gctgtagatt ttcaaatgag acaaaattta
    29941 caggaagagc tagaacgaat atggataaag aagaaaataa ctgcattaat ggtaactcat
    30001 gatgttgatg aagctgtata tatgagtgat agagttatag taatgtcgag agataaagga
    30061 agaattattg atgatataaa tatagatatt ccaagaccta gaattagagg aagccaaaaa
    30121 tatgaagagt acaaaaacaa attaactgat actttatcaa agtgttatga agtttaaaga
    30181 ggagtagaca tgagtcaaat agaaaaatac aatagtttgg ataatacaca acagaaaata
    30241 agaatctcta ttatggatat gataatagat aaaggttcta gtgttacact tcaagaagtg
    30301 actgaatata taagtaaaaa gttgaatatg gaaaaagaat atatagaaag tacactacaa
    30361 tattttattg ataaaaatat aatggttgtt gatggagata gtataaattt tatatatcct
    30421 gtatcagcat tgccaacaaa tcataaagta actttgagag ataatagaag ttttagtgca
    30481 atgtgtgcta tagatgctat agggacatct tgtaccttta accaagatgt aagaataaac
    30541 tctatttgta gtgttacagg tagagagata gaaatagtta taaaaaatga aaagattgag
    30601 tatgtgaata atccgagctt aagggtgctt catataaatc ttgataagta ttcaaattgg
    30661 gctgctaatt gttgaaatat aatgaatttc ttctggacga agagtgattt tgatgcttgg
    30721 acaatcgaag ctgggttatc tgatgacgaa gatatatatt gtttagatat taatgaggca
    30781 atagtagaat cgtataaaat atttaaactc aaacaaaaga taatattgta gatatacata
    30841 aaaaactaaa aattaccttt aggtaaaaat gatagataat atccatactg tataaattag
    30901 tatagagtat ggatatgaaa agtatttaaa tctaaaggta tatttttagt ttttttatat
    30961 gattagatag ccttattaag tatatattta tttataacct ttgcaactcc attttcatta
    31021 ttagtatcag taacataatc tgcaatttcc tttatactat tacgtgcatt tcccatagcc
    31081 acaccaagac ctgcatactt tatcatatgt tggtcatttt cttcatcgcc aacagcaata
    31141 gcattttcta taggtatgtt tagattagca cataatgttt taagtgcagt tcctttatta
    31201 gtagttttac ctaaaaattc tagataaaaa ggagcagacc ttactatagt atatttattg
    31261 aataaatttt taggtagctg ttgtatgatt tcttccaatt tttctggttc atcaactatc
    31321 ataattttac agattttaat agattcatca attttatctt tttgtatata tttgacttct
    31381 atatcattta atttcgcttc atgaagtgta tattttccag gagtttcatt tggtgtaatt
    31441 aaatttgtca ttgtatttat gtgtatttta gtcttatatt ttttacaaac gttattatat
    31501 ataaaatcaa aatcatctaa agtcatttct acatcatgta taattttctc acttttaacc
    31561 tcctgaataa ttgctccatt aaagcatata acataatccc cttcatctgt taaatttagt
    31621 tgatttagaa gctcttttac accaggaaga ggtctgcctg ttgttataac tacttttgcc
    31681 ccagcccttt ttgcctcttg aatggactca aagacttcag gagtaatcct tttttgtgta
    31741 tttaatattg ttccatcaat gtctagtgcg attaatttgt acatatcaac ctccaataaa
    31801 ttatatactc aaatttcctg tgaaaacgtt ggcacgacta gttttgaaca aagtttcagt
    31861 gggaaatatg gtttgttttg tatactatta tatcaagaga taagtaattt agaaagttta
    31921 ataatattaa ttttttgata aaaatattac ctatgtgaga tgagagtgta aaaactttgt
    31981 aatcaataat tccaaaattt ttaattacaa ataatggtat cgtttgcatt gttaatataa
    32041 atataatgta tattatatag ttagaagttt gaataaatag actgatggta atttgttata
    32101 ttagttagtt ttgtgttata aaatattgta attccattaa tcatatgtta ttattcaaca
    32161 tgattgcaat ataaagaata tttaatatat ataataattt ataaaagagt attacatagt
    32221 acatgtaaag ttatatttat aaatacaata aaataaagtt gtaaaggagt gttttaaatg
    32281 aagttttcag agtttaagta tgaaagaccc aattataata gtatgaaaaa agagtttttg
    32341 ggttgtgtag aagatataaa taattctcat aattataaag agcaacaaaa aaatatacat
    32401 aagcttaatt tattgagaaa taaaatagaa acgttgtcaa atatagcatt gataagatat
    32461 agcacagaca cacttaataa attctaccaa gaagaaaaag attattggga tgaatatatg
    32521 cctttatatg aagaattaaa ttcacatttt tataatgcta ttgtaaattc aaagtttaaa
    32581 tgtgatttga taaaagagtt tggagaacaa tttttcacaa tagtagagta ttctttaaaa
    32641 agtttttcta aagaaataat aagtgaatta caggaagaaa ataaattgtg ttcagagtat
    32701 actagacttt tagcctcagc tgagataatg tttgatggga aaataagaaa tttatctggt
    32761 atggggaaat ttatgtattc taagaataga aaaataagag aactagcaaa caaagcatat
    32821 tataatttct ttgaaaaaaa tgaaactaaa tttgatgaca tatttgataa actggttaaa
    32881 cttagagata agatatctaa aaaacttggt tttgaagatt ttgtagagct tggatacatt
    32941 agaatgatga gaagtgatta cagagaagat atgataaaaa gtgttagaaa acaagtatta
    33001 aaatatgtgg ttccaatggc taatgagctt tatgaaaaac aagctaaaag aattggtcta
    33061 gaatatttaa gttatattga tgaaggtgtg gaatttttaa caggaaatgc aagcttaaaa
    33121 ggagattcaa gatacataat tcaaaatgga aaaaggatgt attctgaatt gtcaaaagag
    33181 acgaatgaat tttttaattt tatgttagaa aatgagctta tggatttaga aacgaagaaa
    33241 ggaaaaggag ccggagggta ttgtacttat ataccagatt acaagtcacc attcattttt
    33301 tctaatttta atcaaactgc tgatgatata gatgttttaa cacatgaggc aggacatgca
    33361 tttcagttgt atatgtctag atggattgat atgccagaaa ttaattttcc aacgcttgac
    33421 agttgtgaaa tccattcaat gagtatggaa tttataacat ggccatggat ggacttattt
    33481 tttaaagaag atacagataa gtacaaattt actcacttat catctgcaat taaatttata
    33541 ccttatggag taattgttga tgaatttcaa cactatattt acaaaaatcc taatatagat
    33601 aagtcaaaga gaaaagaaat ctggaggttt ttagagaaaa aatacttacc tcatagaaaa
    33661 tatggtgata attctttttt agataggggc tgttggtggt ttaaacaagg acatatattt
    33721 aaaaatccgt tttattatat agattatgta ttagctcaaa tttgtgcgtt acaattttgg
    33781 aaaaaaatga ttcaagatag agatacagga tggaaggatt atataaatat ctgtaaagtt
    33841 ggaggaacaa aatcattttt agatattgtg agtatgggaa atttgtattc tccatttgat
    33901 gatggatgta ttgagtctat tataggtgat gttaaatctt ggtttgatga aataaatgac
    33961 agcaaattat aaaaaattat gagaatttta ttgtataaaa ttaaaaaatt aaaaaatata
    34021 taaaaaacga ttatttgttg tgaaaatagt cttgttttta actaaattga taaaataaac
    34081 taaaaaagat ttgcacttaa aaaaaaaaga aaatacaaga aatatgcaat atcaacattt
    34141 ggaaaaaaaa gtaaaaatgt atacaaaata catataaaaa aactattgca aattttatag
    34201 aatgtttata tacttaagtc aacagagata gaaaaaagct atttatagaa aacaaaggat
    34261 aaattgctta attttaaatt ttctgaaaaa aataataatc cggatgaaga gtatgggaga
    34321 ctgctttata aaaagcgacc gaagggacaa gtttaatctt acttacccaa aagattagat
    34381 gaaattctca ggtaaaggtg actgtacttg gacggggctc tgaaaatgat tttaacaggg
    34441 aaggcaaatt gggagatttg tttttcctgt tttttattta tcaagaaata aataaaagtt
    34501 tgaaagagag taaaaaaatg ataataatta cgaataatcc aaaagtaaaa gaagaagttc
    34561 aagacagaga agttttgttt aaagacacaa cttatattgg aatcttagaa gcaagtagag
    34621 acttgataca tgaaggttat gaacttttat ctcatccact ctatgggagt gtaaaaccaa
    34681 atgaaacacc ttacaggact gttgtactaa agaaaggaaa tcgtttggat ataaactctt
    34741 taaccttaat tgaagaagca atcatcactg caagtaaatt tcagaataat aaaaagactc
    34801 caaaatggac agaaagtgtt caagatgatt ttagagtaat tgattatgat atattttata
    34861 atacaataca aagaatgcag tatgaataaa gaaaattgtt aaaaagttat taaaacagcc
    34921 taaatattaa atctaattta atattaaata aaatgagaaa tttaattggg gaggataagt
    34981 caaaatggaa aatgtgtatg acttagtaat aattggttca ggaccagcag ggcttgcagc
    35041 aggtctttat ggagcaagag caaagttaaa aactctaatc ctagaaaaag acaagactgg
    35101 tggacaaatt gtaataacac atgaaattgc aaattatcca gggtcagttc caaatgcaac
    35161 aggaccaagt ttaatagcta gaatggttga acagtgtaaa gagtttggag cagaaatgct
    35221 aagagacaac attgttgata ctgagctaga tggagatata aaagttttaa aaggggaaaa
    35281 ggcagaatat agagcaaaag cagtaataat tggtacagga gcaacaccaa gaaagattgg
    35341 ttgtcctgga gaaaaagaac ttactggtaa aggggtttca tattgtgcaa cttgtgatgc
    35401 agatttcttt gaagattttg aagtatttgt tgtaggtgga ggagatagtg cattagaaga
    35461 agcaatgtat ttaactaaat ttgctagaaa agtaacaatt gtacatagaa gacaaggatt
    35521 tagatgtgct aagagtgttg aagaaaaagc aaaagctaat ccaaagatag agtttttatt
    35581 agatacagta attgaagaaa tcaaaggtga tggaatatta gaatcagttg tatttaaaaa
    35641 taaagttact ggagaaacac atgaatactt tgcagatgaa gaagatggaa caatgggagt
    35701 atttgttttc gttggattag atgctcaaac tgatttattc aaaggcaaag ttgatatgga
    35761 tgaaaaaggt tacataataa ctgatgaaga tatgagaact aatataccag gggtatttgc
    35821 agcaggagat tgtagatcta agactctaag acaggttgta actgcaacta atgatggggc
    35881 aattgcatct atagtagcag agaaatatat tgatgaaaaa tttggaaact aatatcaaat
    35941 ttggaaacta atatctgtaa attaaattta atgaacaata ttaaaataaa ataaaaattt
    36001 caaggaggaa taagagaatg ttagatttag ataaggctac atttgaagaa gaagttttaa
    36061 atgcagaagg ttttgtattt gttgattttt ggagtgaagg ttgtgagcct tgtaaagctt
    36121 taatgccaga tgttcataaa ttagctgaga cttatggaga taaaataaaa ttctgtaaga
    36181 tggatacaac aaaagctaga agattagcta taaaacaaaa agtattaggt cttccaacta
    36241 tggctatata caaagatgga gaaaaagtag acgaagttac taaggatgat gctacagttc
    36301 ctaatataga aaacatgatt aaaaaatatc tttaatatgt tgataaagta ttaacagtaa
    36361 aagaaaaatc tatttttctc tgaagataag aagaaaaaag tttttatgtc taactttgtt
    36421 aaaaaaataa ttttaaataa aataattttt ttacaataaa cattttttag taataaaata
    36481 aagatttaag acataaaaac acaagaatat atcttaaaaa aataagataa attgtaaaat
    36541 gatataattt tgagaaaaac tcaaatgcat atacacaaat taaataacag gaggtgcaag
    36601 tatgcgtctt gaattaggga aaatctttat aaaagatatt caatttggtg atgtaacaga
    36661 agtaaaagat ggagttttat tcatcaataa gcaagagatg ctacaagaaa ttggtggaga
    36721 tgagcatatt aaatctatag atatagaatt agctcgtcca ggtgaaagcg taagaataac
    36781 acctgtaaaa gatgttattg agccaagagt aaaagttgaa ggtaatgggg gaatcttccc
    36841 tggtatcatg tctaaggttg acactgtggg agaaggaaaa actcatgctt taaaaggtgt
    36901 agctgttgta actactggaa aaatagtagg tttccaagaa ggtataatag acatgactgg
    36961 agaaggagct aagtacactc cattttctaa attaaataat gtagtagtaa tagctgaacc
    37021 tattgacggt ttaaaacaat acgctcatga aaaagctgtt agaatgatag gattcaaagc
    37081 agcaatgtac ttaggagaag tagcaagaaa tcttactcca gacgaagttt cagtatatga
    37141 aactaaacct cttcttgaat caataaaaga atatccagag cttccaaaag taggatatgt
    37201 ttacatgctt caaactcaag gtttattaca tgatacttat gtatatggag tagatgcaaa
    37261 acaaatagta ccaactttat tatatccaac agaattaatg gacggagcaa ttgtaagtgg
    37321 taactgtgtt tctgcatgtg acaaaaaccc aagttatgtt catataaaca atggggttgt
    37381 tgaagattta tatgcaagac atggtaaaga tataaacttt gtaggtgtaa ttataactaa
    37441 tgaaaatgtt tacctagcag ataaagaaag atcttcaaac tggacttcta aattatgtaa
    37501 atatttagga ttagatgcag ttatagtttc acaagaaggt tttggaaatc ctgatactga
    37561 ccttataatg aactgtaaga agatagaaat gcaaggtgtt aaaacagtta tagttacaga
    37621 tgaatatgct ggacgtgatg gaggttctca atcacttgca gatgcagatg taagagctga
    37681 tgctgttgta acaggtggaa atgccaacca agttgtagtt cttcctaagt tagataaagt
    37741 tattggtcat ttagaagtag tagatgtaat agctggtggt tctgatggaa gtttaagagc
    37801 tgatggaact attgaagttg aaatccaagc tataacaggt gcaactaatg aaacaggatt
    37861 tggtcattta actgctaaag gatattaaga agtatttcat taaacgattg agtaatgtta
    37921 ataaaacata ttatagataa attataataa gtgttataga tatataaaaa tatattagaa
    37981 atataataag gaggattatt atgagtttac ttagtaataa aaaggttctt ataataggtg
    38041 accgtgatgg tataccagga cctgcgatag aagaatgtgt aaaaacagta gaaggagcag
    38101 aggttgtttt ctcatctaca gaatgctttg tctgaacagc tgctggggct atggacttag
    38161 aaaatcaaaa cagagttaaa gatgctgctg ataaattcgg agctgaaaat gttgtgattt
    38221 tactaggtgc tgctgaagcc gaagctgcag gtcttgcagc cgaaacagta actgctggag
    38281 atccaacttt cgctggacca cttgctggag ttgccttagg attaagtgtt taccacgttg
    38341 ttgaggagcc aattaaatca ttatttgatg aaagtgtata tgaagaccaa ataagtatga
    38401 tggaaatggt tttagaagtt gaagaaatag aagaagaaat gtctggtata agagaagaat
    38461 tttgtaaatt ttaatgccta aaagcaaaag gggtgaaact aagagatggg aaaactaaaa
    38521 gcagtacatt atattaatca gttctttgct ggtataggtg gagaagaaaa agctgatact
    38581 aagccacatg tggcagaaac tttacctcca ataagtttac aacttgataa attattaggt
    38641 gaagatattg aaatagttgg aacagtagtt tgtggagata gctatttcaa tgaaaatatt
    38701 gatagtgcaa gtgaagaagt tttatcaatg gtaaaaggtt ttgaaccaca acttttcata
    38761 gctggtcctg catttaatgc tggtagatat ggagttgctg ctggaacaat aactaaagtt
    38821 gtaaaagatg ctttaaatat accagcttta acaggtatgt atgttgaaaa tccaggagca
    38881 gatatgttca aaaaggatgt ttatgtagta gaaacttctg attctgcagc aggtatgaga
    38941 aaagcacttc ctaagatagc taaacttgca gtaaaacttg ctaatggaga agaaattgga
    39001 actcctaaag atgaaggata catagctaga ggaataagag ttaactactt ccatgaagac
    39061 agaggttcta agagagctgt tgacatgtta gttaagaaaa taaaaggtga accatttgaa
    39121 actgaatacc caatgccaaa ctttgataga gttgacccaa gcaaagctgt aaaagattta
    39181 tcaaaatgca aaatagcttt agttacttct ggtggtatag ttccaaaagg gaatccagat
    39241 agaatagagt cttcttcagc ttctaaatat ggaacttatt ctatagcagg agttatggat
    39301 ttaacagaag agacttatga aactgcacat ggtggatatg acccagtgta tgcaaattta
    39361 gatgcagata gagtattacc tgttgatgtt cttagagact tagaaaaaga aggtgtaatt
    39421 ggaaaattac atgagacttt ctatacaact gtaggtaatg gtacatctgt tgcaaactct
    39481 aaaaaatatg cttctgaaat tggagcagca ttagtggctg atggtgtaga tgcagtaata
    39541 ttaacttcta catgaggtac ttgtactcgt tgcggtgcaa cgatggtaaa agaaatagaa
    39601 aaaactggac ttccagtagt tcatatgtgt acagtagtac ctatttcatt aacagtaggg
    39661 gctaatagaa tagttccaac tatagcaata cctcatccac ttggaaatcc agcgcttgac
    39721 cctacagaag aaaaagccct aagaagagga cttgtagaaa aagcattaaa tgctttaact
    39781 acagaagtag atggtcaaac agtatttgaa aaataaaaat aacacacaca tatattatat
    39841 agataaaaat ataaacacac actaaaaata aaaaataact atacacaaaa aaataatata
    39901 gatttcatga atggataaat tggagttatt cattcatgaa atcttaaaaa atgccaaaat
    39961 acataaacaa taatagaatt aaatatacaa taaaatacaa taactagaat ttttaataag
    40021 attaaaaaat aagtgttcat aaaatttatg gaggtgcaca aaatgactta tccagtttta
    40081 aaaggggcag gctatgtact tattcatact ccagatatga tagtgcaaaa tggaagtact
    40141 tgtacagttg aaagagcaac aaatccagac tcagaatttt taaaagaagt aagtaatcat
    40201 ataagaagtt atgaagatgt agttaactac atgccaaatc aagtttatat aggaaataga
    40261 agaccagaag aattaagaga tttaccaatg ccatggtgtg aacaaaagat tgagggaact
    40321 agaaatggta agtttggaga aataatgcct caagatgagt tcatagcttt aatgcaaata
    40381 agtgatgcat ttgatttagt aaaattatca caagaattta ttgatgaagt aaaaccaaaa
    40441 attgaaaaca actaccctga aattgcacca tttgtaggta aattaaaggg tgatgatata
    40501 gaagaaggta aagaattagt agcaacacac atagctgaag gattatacca tgatggaaaa
    40561 ttcgttggtt atgtaaaaag agcacatgat gtagatgtta acttaaatgc ccatacaatg
    40621 tttgaaaatc tagtagtaaa agcatctgga gttttatctg ctattcaaat gctaagacat
    40681 agtaaaatag accctgctga aatagattat gttattgagt gttcagaaga agcttgtgga
    40741 gatataaacc aaagaggtgg aggaaacttt gctaaatcaa tagctgagat agtaggactt
    40801 caaaacgcaa ctggttctga cacaagagga ttttgtgcag caccaactca tgcattaatt
    40861 caagcagcag ctttagtaaa agctggtata cataaaaatg taatggtagt agcaggtgga
    40921 gcaagtgcta agcttggaat gaatgctaaa gaccatgtta aaaaaggtct tcctgtactt
    40981 gaagatgttg ttggaggatt tgcagtactt gtatctgaaa atgatggtgt aaatccagtt
    41041 ataagaactg atttaacagg taagcatact gttggaactg gttcttcacc acaagcagtt
    41101 atgacagcac ttataacttc aggtcttgat agagctaatt taaaaataac agatgttgat
    41161 gtatattcag ttgaaatgca aaatccagat ataactaagc cagcaggagc aggagatgtt
    41221 ccagaagcaa actacaaaat gataggagca cttgctgtta aacgtggaga cttagaaaag
    41281 aaagaattga aagattttgt ttctaacaaa ggattaccag gatgggcacc aactcaagga
    41341 catataccat caggagctcc ttatatagga tttttaatag atgatttaac tacaggaaat
    41401 agaaatagag ctatgatagt tggaaaaggt agtttattct taggaagaat gactaactta
    41461 tttgatggag tatcttttat agctgaaaga aatacaggtg ttactgaaga gacttcagga
    41521 atatctaagg atgaaattaa gaagataata gctgaatcta tgaaaaaact agcattagat
    41581 atgttagaag aataggggtg aggatatgtc aaaaaaagta atcgcagatg tattcttaga
    41641 agtagctaat gcaatagaaa gcggcgaatt tggcaaaaaa gtaaaaattg gtgttactac
    41701 acttggaagt gaacatggtg tagagaacat ggtcaatggt gcacaattag caaaatctaa
    41761 tttatttgat attgtgctta ttggaccaaa agtggaaact gaccttgaag tagttgaagt
    41821 taatgatgaa aaagaaatgc atgcaaaaat ggaagaatta ttagattcag gatatattga
    41881 tgcttgtgtt actatgcatt ataattttcc aataggtgta tctacagtag gtagagtaat
    41941 aactccagca aaaggaaaag aaatgatact tgcaacaaca acaggaacaa gtgctactaa
    42001 tagaatagag gcaatggtga gaaatgccat ttatggtatt gctacagcga aatcaatggg
    42061 taacaaatgc ccaaaagttg gaatacttaa tgttgatgga gcaagacaag ttgagaagtg
    42121 cttaaaagaa ttaaaagata atgggtatga tatggaattt gcggattcaa ttagagcaga
    42181 tggtggatgt gtaatgagag gtaatgattt acttgtaggt gcacctgatg ttatggttac
    42241 tgatacatta tctggaaata tatttatgaa agtattttct tcatatacta caggtggaga
    42301 ttatgaagct caaggatttg gatatggacc tggagttgga gaggactatg atagaaaggt
    42361 acttatagta tcaagagcat caggttctcc ggtagtagca aatgctttaa aatacgctta
    42421 tgatgtcgta aagggagata taagtaatgt tgcaagaaat gaatttgcaa aggttaaaaa
    42481 agcaaaattt gctgacatta tatcctctct tactaaaaaa gaagttaaag ctgaaaaagt
    42541 agaagttaaa atgccagata aagagattgt tactcgtcaa atagctggtg ttgatataat
    42601 ggatttagaa gatgcagtgt ctgagttatg gaaaaacgga atctatgctg aaagtggtat
    42661 gggttgtaca ggtccaatag ttttagtaaa tgaagctaaa ggagacttag cagttgaaac
    42721 tttagttaaa gctggatata ctgcaaaata agtacacttt ttatgtaaat aagaacatat
    42781 acttataatc aataaaatta taagtatatg ttctttttat tttctacttt gtcaatgttt
    42841 atatattaac ataatctttt tatttgattt tctagctaat ttatcatatt tgttcaattg
    42901 aatttaagtt tttagctaaa taaaactaat aaaatattaa agtaaaatta ataaaatctg
    42961 aaaaaatttt agaaataaac tatctattag ataaaaagaa ggctaattag tgatataata
    43021 taattaggat aaaatttatt atttggaggc aaaatcatga gcaaagtaaa aaaagtagta
    43081 gaattgttgg aatctaaagg tattgatgca ctatatctaa caaagaaaac taatgtaaac
    43141 tatataagtg gttttcctga tgaagaagca tatgcagtga tttgtaaata tggaaacttt
    43201 ttagttactg atagtagata tatggagctt gcggaaaatg tttgcgaagg ttttgaaatt
    43261 ataaattggc ataattttga tagaagtgtt gcaaaggcag ttaaaagtgt atgtgataaa
    43321 gtgggaataa agaaacttgg atttgaaaga actaatatag tgttcgataa atatgaagaa
    43381 cttaaaaatc tgattgagaa ggataatgga gaattaatac ctacggaaaa tattgtagag
    43441 actttgagat atataaaaga cgaagaagaa atcaaaaata caagaaaagc ttgtgaaata
    43501 gcagataaag cattagaaga attgattcca catataaaag ctggagttag cgaaattgaa
    43561 ctggctacga agttagagta ctttatgaag atgaatggag cacaaaatat aggatttgaa
    43621 actatattga tatcaggagc aaagacttca ttgcttcatg gtaagcctag tgataagatt
    43681 atagaaaaag gtgattttgt acttatagac tatggtgcta tgtataatgg ttatatatct
    43741 gacacaacta gaacttttat agttggggaa gcttctgaaa agcaattaga aatatataat
    43801 ttagttaagg aagcccaaaa tgtaggggtt gaaaacatga aagttggtgt acatgcgaca
    43861 attccagatg ctgagataag aaaagttgtc aaaaaatacg aagactatta ctatcagggt
    43921 ataggacatg gagtcggtag agatgttcat gaagaacctt tcattggtaa ttatggtgat
    43981 aaaatcatag aagatggatg tataataaca atggaaccag gtatttattt ccctggatgg
    44041 ggtggagtta gaatagaaga cactgttttg attactaaaa atggaccaga aagacttact
    44101 aaattcccta aagatttgat gattttagac aaataattta atttatatat atttttacat
    44161 aaaatataac ataatctcac tattaagccc tatttacata ttatgataaa gagggcttaa
    44221 ttttattgtg agaggtgata atgtccatgt ataaaaaaca taaatttata aaaaatataa
    44281 aacaagcctg gtataaaatc aaactaattg atagatgcct tataattgta atggcaatat
    44341 taatgtttca atctatatac aatttatttg ttaatgaagt aaattcacaa gacactacaa
    44401 ctattgatgt agtagtaaga actacttcag cagctatatt tggatacttt ttaagtgtta
    44461 attttataaa gagaccttca agaaagtata taaatactga tgtatcttca aattttttta
    44521 tagataataa tttatctaag aaaagtcaag aatcaagtca gaataatgta atgaatgtca
    44581 aaaataccat tggatttact tcagaaactg ataattatga aaagaaaata cctactaata
    44641 atactgaaga ttttgaagat ggagagacta gtgaattaca aattgttata gctactgtaa
    44701 tttgtgtagt agcattaaca gtactttttg ttgtaagaaa ttttacaact acaacatcag
    44761 cttctttagg tactatttca cagatgagag attttgtctc aggatgcgtg ggttttttac
    44821 taggttgtcc aagtagacct gattaaaaat gtgattacta ataaaaaaga ttgttaaaag
    44881 tatcagtata ataatactta gacattaagg catataatta taatcttata agatttgata
    44941 tcctattttt atactgatac tctaaaatat ttattaaaac atttttaata ttacatttaa
    45001 ataaaatatt atggctacat aaaagttaat ttatatgaat agatgccata tattcaataa
    45061 aaagtttcat actatgagat atgtattgat ttcttctcca aagaacccca atatttgcag
    45121 taattgcacg ctctaatggt attgaacaga gattttttgt attttgaaat atttctttat
    45181 atagtattgt tgaagccaag tcattttcta gtaaataacg tatggtagaa agttggtttg
    45241 agtgtaaaat tatatttggc ttagcttttt caagtctttt tgtaataatc ttatagtgat
    45301 aagaaccttc agataagatt acaaaaggta cattttttaa catataactt gatataatgg
    45361 ggtgttttgc caattcattt ttgggatttg taactaaata taattctgtc ttatagattg
    45421 tctttgaatc tatatcatca taaatatcac tatcaattat accaatacaa aaatcaagtg
    45481 tagattcttc aatcatttta gctccaacaa atgttggaac ttcaaaaatt ttaagctcta
    45541 tatctggata aattacatta aatctaggaa gtattttcga aagtaaaaat gtacctaaaa
    45601 ctgtaggaat acctattttg agagaagctt ttctcttttt tcccaaatcc agtgcgtcac
    45661 attgaaaatc ctcaaattgt tttataaaat gttttgactt gtctaaaaag atttttcctt
    45721 caggcgttaa ctctatttta ttacctattc tataaaaaag ttcaaagcca agttcttttt
    45781 ctaattcttt aattgctaat gttatggatg gttgagaaat gtgaatactt tccgcagcct
    45841 tagtcatgtt tttatattta cagacagttt gaaaatagta taaatagttt atattcattt
    45901 ggtattactt cctttcattt acgtattagt gacaagtata taattaacaa tagtataagt
    45961 tttgtatatt gttgtaaaaa aatagaatag ttttaaacta tcatatcata agtttttgat
    46021 attttcaatc tattgagaat agtgttatta ttaaattaac aaaagagaat agctgatatg
    46081 gtttactcta aatcaatcta taatacagtt atatcaacga atattaaaaa aatatctatt
    46141 aaaaaataaa aaatattttt acaattaaat tgttaattaa atcgtaaaga aaaaaatgat
    46201 attatcaaga taaaattttt ttaattagaa gtgttaattt aataacaaaa tagagtctta
    46261 gggagaaagg agaaatatat tttttaataa tatttgttaa tttaataaca aaaaatgaaa
    46321 gggagtgatt tggtgaagtt tgaattgatg gattttttaa tgaatccttt tgtccttatg
    46381 tttgctgcag taattacagg aattttattt ggaaaaatta aatttgggaa gtttaatttt
    46441 ggggtatcag gagcattatt tacaggatta tttattggat ggcttgcata tagcttggga
    46501 aatttaataa tagcaaaagg agaaacagca gcaggatata aggcagcaac tgtaatgatg
    46561 gggaatggaa ttatttctcc tgacttcttt gatttctttt taataatatt tgttgcagca
    46621 gttggtctat tggcagcaaa agatatgaaa gctgtattaa agaagtatgg agcaagattt
    46681 gtaattttag gcgttcttat aactttcata ggtggctcta tgacttatgc aatgacttta
    46741 ttatcaagtg ataaaggaag tagcgcttat gaagtttctg gtgtttacac aggagcatta
    46801 acaagttcac ctggattagc cgctgcttta gaaacagctg gtaaacatgc agaagatgta
    46861 tcaaaagaat ttgaaaaagc ttcaacaaaa gataaagaag aaattttaaa agtagtcgac
    46921 ccagaaggaa aattagatgt gagcacaact acatcactga ctcaagagca aatagataag
    46981 tacattgcat atgctgaagc tggtgttggt ataggtcatg cagtcgcata tccttttgga
    47041 gttttaatag taatcttagg tgtaaatttc cttccaaaat tatttaggat ggaccttaaa
    47101 gaagaaagaa gaaaatatga gaaggaaatg aaagaagcaa gagatagtgt ttctggtaaa
    47161 acgataccag aagtcccatt taatataata acatttttct tgacatgttt agctggatac
    47221 ttagttggag gaatacatgt atttatggga ccactagggt actttacact aggagcaaca
    47281 ggaggttcac taattgtatc tctagttctt ggatatatag gtaagatagg ggtaataaat
    47341 tttagaatgg aagaaaaggt tttaaatatt ttaaaacaaa tagggctagt atttttctta
    47401 gcaatagttg gattaagata tggtggaaaa gtagttgatt caattatgac atctggtatg
    47461 cacctagctt tagtagcaat agcagtgggt gttacagcta tgatgatagg attcttagtt
    47521 ggtaaatatg tatttaaatt aaattggatt ttactatctg gagctgtctg tggtggtatg
    47581 acatcaacac caggccttgg agctgctgtt gatgctcttg atagtgatga cccagcagca
    47641 ggttatggtg ctacgtatcc atttgcatta ttaactaaag ttatattggt tatagtttta
    47701 cacaaacttc caatgtaaat aagattttat atggggggat atttatgaat aatgaaggaa
    47761 catttgaaga actaagtgga agattaagaa ataaaaaatt gtgtgattta ataatgaatg
    47821 cagatgaagc tgctaaattt ataaaggatg ggatggttgt tggagttagt ggatttacac
    47881 cttcaggtta tccaaaagca gtaccattag cagtttcaga aagagctaaa agtggagaaa
    47941 agataaaatt aactgtatat tcaggagcat ctttaggtcc agaagttgat ggagcatggt
    48001 cagaagcagg tataattgaa agaagacttc cttatcaaac taattcaata cttagaaata
    48061 atattaataa aggtgttgtt gattatatag atatgcacct aagtcattct actcaatttt
    48121 taaattatgg aactataccc aaagtagatg tagctatagt agaagcactt gcaataactg
    48181 aagatgggaa tattatacca actagtggaa taggtaattc tccatctttt ataaaaagtg
    48241 cagataaagt aatagtagag ataaatcttg caaaaccaat ggaaatggaa ggtatggcag
    48301 atatatatat tacggaaaat ccaccaaata gaaaaccaat agaaataaat catcctaaag
    48361 atagaattgg aacaacatat ataccttgtg gtttggataa aattgcagga atagtaatta
    48421 ctaatatgca agataaaacc cgaccattgg gtgtagtaga tgaagcttcg aaaaaaatat
    48481 caaataatat tattgctttt ttaagagaag aagtaaaggc aggtagactg tcaaagaatt
    48541 tacttcctct tcaatctggt gtaggaagtg tagcaaatgc agtattatat ggattatgtg
    48601 aatctgaatt tgaaaattta acttgttaca cagaggttgt acaggattct atgttggatt
    48661 taataagaat gggcaaagtc acaatggcat ctactacatc tgtaagtcca tctccggaag
    48721 gattaataaa atttgaaaaa gatattgatt tttttaagga taagattata ttaagacctc
    48781 aagaaattag taataatcca gagatagcta gaagaattgg tgtaattgca atgaacactg
    48841 caattgaagt tgatatttat ggaaatgtaa attccactca tataatgggg tcaaagatga
    48901 tgaatggaat tggtggttct ggtgattttg ctagaaatgg agcaataact atatttagta
    48961 ctgagtcaat tgcaaaaaat ggtgatatat catcaatagt acctatggta tctcatgtag
    49021 accacactga acatgatgta atggtaattg taacagaaca aggatatgct gatttaagag
    49081 gtcttgcacc tagagaaaga gctataaaaa taatagaaaa ttgtgcccat ccagattata
    49141 aagaacaact tagagattat ttaaatagag cttgtaaaag tggagcaaaa caaacacctc
    49201 acatattgga tgaagcttta tcatggcata gtaaatttat gagtacaggt acaatgaaaa
    49261 aggctgaaac ttttaaaagt gcattataaa atatttaata aattggaggt agattttaaa
    49321 tgggaaaagc agtggaaaat tttgaagatt taagtaagga atacattaat ggttatattg
    49381 agagagccag aaaagctcaa agagagtttg aatgttatac tcaagaacaa gtagataaaa
    49441 tagtaaaaat agttgggaaa gtggtgtatt ataatgctga atatttagct aaacttgctg
    49501 tagaagagac tggaatggga gtatatgaag ataaggtagc taaaaataaa agcaaagcaa
    49561 aagttatata taacaattta aaagataaaa aatcagttgg tataattgat atagatagag
    49621 aaactggaat aacaaagata gctaaaccgg ttggagtagt agcggcaata actccttgta
    49681 caaatccaat cgttacacct atgagcaatg caatgtttgc gcttaaggga agaaatgcaa
    49741 ttattatcac acctcatcat aaagcaattg gatgtagtac aaaaactgtt gagatgatta
    49801 acgaagaatt agaaaaaata ggagcaccag aaaatttaat acaaatactg gaccaacaat
    49861 caagagaaaa cacaagaaat ttaatttcat cagcagatgt agtaattgcc actggcggaa
    49921 tgggaatggt aaaagctgca tactcaagtg gaaaaccagc acttggtgtg ggagcaggaa
    49981 atgttcaatg tattatagat agagatgtag atattaaaga agcagtacct aaaatcatag
    50041 caggaagaat ttttgataat gggatcattt gttcaggcga gcaatcagta atagtagcag
    50101 aagaaatgtt tgataagata atggatgaat ttaaaaataa caaaggtttt atagttagag
    50161 ataaagcaca aaaagaagct ttcagaaatg ctatgtttgt aaataaatct atgaataaag
    50221 atgcagtagg tcaatcagtt catacaatcg caaaaattgc aggtgttgaa ataccagagg
    50281 atacaaaaat aatagtaata gaagctgatg gaccaggaga agaggatatt attgcaaaag
    50341 aaaaaatgtg tccagttata tctgcatata aatataaaag ttttgaagaa ggtgtagcta
    50401 ttgcaaaagc aaatttaaat gtagaaggaa aagggcatag tgtatctata cattcaaata
    50461 cagttaagaa tatagaatat gcaggagaaa atatagaagt atcaagattt gttattaatc
    50521 aatgttgtgc tactagtgct ggaggaagtt tctttaatgg tcttgcacct actaatactc
    50581 taggttgtgg ttcttgggga aataacagta tctctgaaaa tcttgattat aagcatctaa
    50641 ttaatatttc tagaattgct tattatatgc cagaaaatga agttcctaca gatgaagaac
    50701 tttggggata aaatttagac aaaaaatatt cattctaaat taaaataaga atatatttta
    50761 atttagaatg aatttaagac ataaattaaa tttaaattag tctattagac caaatttaaa
    50821 atattaagag acatatagaa gaaggaagta ttataattta aaataaataa aaaattctat
    50881 aaaagagaag gagtggtttt attatggcat taatgacagg agctcaatat attgaaagtt
    50941 tgagaaaatt aaatactaag gtttatatgt ttggtgaaga ggttaagaat tgggttgacc
    51001 atcctatgat tagaccatct ataaattgtg tagcagcaac ttatgactta gctcatgacc
    51061 ctgaatatgc agatttaatg acagttactt caaatatcac aggtgaaaaa ataaatagat
    51121 ttggtcatct tcatcaaagt actgatgatt tgataaaaaa agtaaaaatg caaagactat
    51181 gtggtcaaaa aacagcttct tgtttccaaa gatgtgttgg tatggatgca tttaatgcag
    51241 tatattcaac aacatttgaa tgtgataaag cccatggaac taattatcat gataattttg
    51301 taaaatactt aacttatata caagaaaacg atttagtagt tgatggagct atgactgacc
    51361 ctaaaggaga tagaagttta tcacctagtg ctcaacctga cccagatatg tttcttcata
    51421 tagtagaaag aagagaagat gggataattg taagaggtgc aaaggcacat caaactggtt
    51481 caataaattc acatgagcac cttataatgc ctactataag catgactgaa gcagataaag
    51541 actacgctgt atcatttgca gttccttcag atgctgaagg agtatttatg atttatggaa
    51601 gacaatcttg tgacactaga aaattagaag aaggtgcgga tgttgattta ggaaataagg
    51661 agtttggagg tcaggaagct ttagtagtgt ttgataatgt atttgttcca aatgatagaa
    51721 ttttcttatg tggagaatgg gatttctctg gtatgttagt agagagattt gcaggatatc
    51781 atagacaaag ttatggtgga tgtaaagtag gagtaggtga tgtaataata ggagcagcag
    51841 ccttagcagc tgattataat ggagcaaaca aagcttcaca tataaaagat aaactaatag
    51901 aaatgactca ccttaatgaa agcttatatt gctgtggtat agcatgttca tcagaaggtc
    51961 acaagacaga agctggaaac tatcaaatag atttacttct tgcaaatgta tgtaaacaaa
    52021 atgtaactag atttccttat gaaatagtaa gacttgcaga agatatagct ggagggctta
    52081 tggttactat gccttcagaa aaagacttta aatcagacct taaagttgga acaagtggaa
    52141 tgactattgg cgaagtatgt aacaagtatt ttaaagcttc ttcagtagct tcaacagaag
    52201 aaagaatgag aatattaaga tttttagaaa atatatgtct tggttcatct gctgttggtt
    52261 atagaactga gtcaatgcac ggggcaggtt caccacaagc tcaaagaata atgatttcaa
    52321 gacaaggaaa cataaatcaa aagaaagaat tagctaagac aattgcagga ataaaaaaag
    52381 aagaagcttt aaatttataa aaagttgata tataaaggga aattatatat taatgtttat
    52441 taattaatga aaaaatatgg agtataagag ataattataa aattatggtg gtttttagct
    52501 aagtaaagaa attttttata aggagaattt acacatgacc tgtggagtta gattttgtgg
    52561 cggctgtaac cctagatacg aaagagggaa ggctcttgca ataatcaaag agcacttcaa
    52621 tggtagagta gattttagta tagcacaaga gaacttggag tatgatttgc tacttataat
    52681 tggaggatgc gcaactctat gcgcatccta tcaacaatat aaagtgaaaa atgaatgtgt
    52741 taagatgtgg gattttagcc atatagaaag agttataaat gtgattgaat cagcaatttg
    52801 tgaaacttaa aaaagctaaa tggggggatt tcattgagtt ggcgagaatt gtatcaaagt
    52861 aagttatgta gtgctacaga agctgtaaaa cagattaaaa acggagatac tgtagtattt
    52921 gcacattgtg taggtgaacc tcctgcacta gtagaggcta tgattgaaaa tgctgaacaa
    52981 tataaagatg ttgagattaa acatatggta agcttgggta gtggtggata tactgctaag
    53041 ggaatggaag ctcattttag agtaaatcca atgtttgtaa gtggaaatgt aagaaaggca
    53101 attgaaaacg gagatggtga ttttacgcct acattcttcc atgaagtacc aaagttgctt
    53161 agagaaaaaa gattaaaatg tgatgttgtt ttagcacagg taactccacc tgatgaacac
    53221 ggatattgta gcttagggac atcagttgat tatacttatg aagctattaa aactgctaga
    53281 acagtaattg ttcaagtgaa tgaccagttt cctagaactt atggtgaggt agtccatgta
    53341 tcagattttg actatatagt ggaaaaatca caacctttat atgaattaga acctgcaaag
    53401 attggagaag tagaagaagc aattggtaaa aactgtgctt cattaattga agatggttct
    53461 actttgcaac tagggattgg tgggatacca gatgcagtta tgttattttt aacagataaa
    53521 aaggatttag gaatccattc agaaatgatt tcagatggga ctttggctct ttatgaaaaa
    53581 ggtgttataa atggtaaata taaaaatttt gataaagaga aaatgacagt tacgttctta
    53641 atgggtacta aaaaattata tgactttgta aataataacc ctgcggtaga ggtaaaacct
    53701 gtagactatg taaatcatcc agcaattata atgaaacaac ataagatggt ttccataaat
    53761 tctgctatac aagttgattt gatgggacag gtagttgcag aggctatggg acttagacaa
    53821 tttagtggtg ttggaggtca agttgacttt atacgtggag tgtctatggg agaagatgga
    53881 aaagcaatta tagctatgcc ttcaataact acaaaaaaag atggtacagt aatttcaaaa
    53941 attgtatcta ttgtggatga aggtgcacct ataacaacat caagaaatga tgttgactat
    54001 attgtaacag aatatggtat agcagaatta aaaggaaaat ctcttagaga aagagctaga
    54061 aatttaataa atatagctca tccaagtgta agagaaagtc tagcaataga gtttgagaag
    54121 agatttaagg aaaaatatta ataatagaga ggtgttaata atggaagcac ttagagtagt
    54181 tccaaagata ttttattttg atacatttaa agaatttaat gaagaattta aaataggaaa
    54241 aaatgattta gtaattacta atgagtttat atatgagcca tatatgaaac ctcttggaat
    54301 agatacaaat ttaatttttc aagaaaagtt tggaacaggt gaaccatctg atgaaatgat
    54361 agattccatg acaaaggaaa tgaagaaata caattttgat agaattattg cgtttggagg
    54421 aggaacaata gttgatatat gtaagatatt agcgcttgat gttccagaaa agtctattga
    54481 tttatttgaa ggagaagtac cacctaaaaa aataaaagag ttagtagtag ttcctacaac
    54541 atgtggtaca ggtagtgaag taacaaatgt agctattgca gaattaaaat ctaaacatac
    54601 taaaaagggg cttgcagtag aagaaacata tgcagactat gcagtgctaa ttccagagac
    54661 agtaaaaggt ttaccttata aattctttgt tacaagctct gtggatgctc ttatacatgc
    54721 tattgaatct tatctttctc caaaagcaag tccatttaca gaaatgtatt ctctgcaagc
    54781 aataaaaatg attatggatg ggtataaaaa gatagttgat aaaggagaag aagagagatt
    54841 taatcatctt agagactttg tccttgcatc aaattatgca ggaattgctt ttggaaatgc
    54901 tggttgtgca gcagttcatg cactatctta ttcaataggt ggagctttcc atgttgcaca
    54961 tggtgaagca aattatcagt tctttactga agtatttaag atgtattcta gaaaaaaacc
    55021 taatggaaaa attataaaat gtacaaaaat tttagcagat gcccttgaat gtgaccctaa
    55081 ttgtgatgtt tatggagaat tagaaaagtt tttaaacaag ttaatagcta aaaaagcttt
    55141 gagagaatat ggaatggtgg aagctcagat agatgaattt acagatagta caatagcaaa
    55201 tcaacaacga ttacttgcta ataattatgt agaacttaat agagaggaaa taagagagat
    55261 atttgcaaat ctttattaat aaaatttttt atttatatgt atagtcaaca taagcaatgt
    55321 taattatatt tatgtacaaa taaaaacgag ggaacttaaa tttaattaaa gttaagttct
    55381 cttattttta tatggagtta aatgtaagta tatttttgat ttaaaatgta cttacattta
    55441 agtctattac tttatttgga acaatttgta gaatttcaaa ttccttgaca gtaataagta
    55501 agtaattgta taatcaaact gcaatatatt aataatatta gtgaaaatga aaggatataa
    55561 aatatgtata aatcagaaaa tttttcaaaa aaatctgtat taataaattc atttttaagt
    55621 aaatttttaa aaataattgg atggggttta gtaagtttat ttacattatc agcattagta
    55681 ctttcaacta tttccattat aatcggatgg gctgtaatac ttcctatcca agtatgtgca
    55741 gtatttttaa ttataggagg agtttgtatt tttaaaggta agaggttagg agaccaaatt
    55801 tctcgttata aaaaatattg tacaattata aacaatagaa atattattcc agtagaactt
    55861 attgcagaaa atacatctaa atcattaaat tttataataa aagatgtaca aaagatgata
    55921 gacaaaaatt actttataaa tacttacatt gataaaagaa ataatcagat tgtactgaca
    55981 aatgaagatt ttgttccaac aagatatgaa gatgtagcat atgaagttaa agaagaagaa
    56041 aagactgatg aagacaatga agttgataca attataaata aaggaatgaa ttatctaaca
    56101 catataaaag aagctaataa aaatattaaa tcagaatcaa tgtgcgataa aattgtacaa
    56161 gtagaagatg ttacaagtaa aatatttgat gttgtaaaac atgacccatc aaaacttact
    56221 caaatacaaa aatttatgga ttattatctt ccaactactt tgaagctatt aaattcatat
    56281 catacattgg aagaacaagg cattgataga gaaaatataa caacaactat ggaaagtatt
    56341 gaaaatacaa tgaatacgat tgtagtagct tttgaaaatc aattggacta cctgtttgaa
    56401 gatgaagcaa ttgatatttc tacagatatt actgttttag agaatatgtt agttcaagaa
    56461 ggattaacga gtggtaaatt ttaacttcaa tagaaaaaat attctgttat ttttaaacaa
    56521 ttaattagtc ataaagtata aaatatgtgt tagataagtt aagcagtact ttatgaagga
    56581 agaggagaga aagatataat gaataattta gatgatatac cagttatgcc aactttgacg
    56641 cttgacccat ttggagaaga atcaaacact agtgatatag ataattctga cttattaatg
    56701 aaaaaggatg aaaaagaccc agaagaagaa aagctgtctg aatctgaacg taagatggta
    56761 aaggaatttg cggaaaaaat agatattaca aatacaaata tgattttaca atatggagct
    56821 ggtgctcaaa aaaaggtggc gagcttttct gaaacagctt taaagagtgt caaaacaaga
    56881 gatttaggag aagttggaga tatgcttaca aatctagtta ctgatttaaa agcattttca
    56941 gcagatgaaa aagaacaaag tggttttttg ggaattttta aaaaggcaaa taataaaatt
    57001 tcaaatctaa aaactaagta tgatagtgca gaggtaaatg tagataaagt aagcaaagaa
    57061 cttcaaaagc atcaggttaa aatattgaaa gatatagcaa tgcttgataa gatgtatgag
    57121 ttgaacttag cttattcaaa agaacttact atgtatatta tagccggaaa acaaaaacta
    57181 aaagatatga aagaatatga gatgccaaag ttgagagaaa aagctcgttt atctggttca
    57241 acagaagatg ctcaatctgt aaatgatatg gtttcacttt gtgacagatt tgaaaagaag
    57301 attcatgact tagaattaac tagaatggta tcgcttcaaa tggcgccgca gataagattg
    57361 gttcaaaata gtaataatct gatggcagaa aagattcaat caactatagt aaatactatt
    57421 ccattatgga aaaatcaaat agtacttgct cttggaattt ctcatttaaa tcaagctatg
    57481 aaagcacagc gtgaagttag caatatgaca aatgagcttt tattaaagaa tgcagaaact
    57541 ttgaagatgg gaacaataga aacagcaaaa gaatcagaaa gaggaattgt agatatagat
    57601 acaattaaga aaactaatca atctttaata tctactattg atgaggtcgt taagatacaa
    57661 catgatggta gaataaagag acaagaagca gaagttgaat tatcaaaaat agaaaatgaa
    57721 cttaaaagta agcttcttga atttacagtt aaataaaaat tatactaaga taaaaaagag
    57781 actatcccaa aatagagata agtctctttt tcattgttta aatgattaaa gtatatactt
    57841 atattataaa tttctattat cttttaacat aacatcatga gccccacctt caactatact
    57901 agtagaagat acaagcgtaa gtttagcatt tttttgaagt tcaggaatac taagtgctcc
    57961 acagttacac atagtagaac gaactttact taaagaaaga gttacgttgt cttttaaaga
    58021 accagcataa ggcacataag aatcaacacc ttcttcaaaa gaaagtttct tatctccacc
    58081 aaggtcatat ctttgccagt ttctagcacg agcagaacct tctccccaat attctttcat
    58141 gtaactacca tttatattaa ctttgttagt tggactctca tcaaagcgag agaagtatct
    58201 accaagcatt ataaaatctg cacccatagc taaagctaga gttatatgat ggtcataaac
    58261 gataccacca tcagaacaaa ttggaatata aatacctgtt ttttcaaagt attcatctct
    58321 agcttgagca acttcgatta tagaagtagc ttgtccacgt cctatacctt tttgttcacg
    58381 agttatacat atagaaccac caccaatacc aactttaacg aagtcagcac cagcttcagc
    58441 taggtaaagg aatccttcac ggtcaactac atttccagct cccactttaa ctgtatcacc
    58501 atatttttca cgaatgaaat caagagttat tttttgccac tcagaaaaac cttctgaaga
    58561 atctatacat aaaacatcag caccagcttc aactaaagca ggaacacgtt cagcaaagtc
    58621 tctagtatta ataccagctc caactacata tcttttagaa gaatctaaaa gttcaagtgg
    58681 attttcttta tgagaagaat aatctttacg gaataccatg tacataagat taccattatc
    58741 atcaagtaca ggtagagagt taagtttgtg gtcccatata atgttgtttg cttcttttaa
    58801 agtaacatct ttgttagcgt aaactataga tgacatagga gtcataaatt cactaacttt
    58861 agtatctaaa tccatacgac ttatacgata atcgcgactt gcaacaatac ctaataattt
    58921 accagttgaa gttccatctt cagtaacagc tactgtagaa tgtccagttt tttcttttaa
    58981 gtcaagtatg tctttcaatg tgttatcagg tttaatattt gaatcactta caacaaaacc
    59041 agctttgtgg gatttaacac gtgccaccat agcagcttca ttttcaatag tttgagaacc
    59101 gtatataaat gaaataccac cttctttagc aagtgcaata gccattttgt catcagaaac
    59161 agattgcata atagcagaag tcaaaggtat attcatataa atatctgctt cctcgccctt
    59221 tttgaattta gtaacaggtg tttttaaact tacattagca ggtatacaat cagtagaaga
    59281 gaaacctggt acaagaaggt attcactgaa agtatgtgat ggtgtatcaa aataaaacgc
    59341 cattttttaa tcactcctta tatttttata ctttttataa ttgatagtat taattataac
    59401 ttattcttta attttattaa agtattttgt caaatattga gatttttgaa aaatttaaac
    59461 tattttaatt gaatttgttt aatatatatt gccttatagg gtaaagttgt atattaaata
    59521 atgtttagta tttaatagta gctaatttga aattaatatt tagttattca tacattaaag
    59581 ttgtatattt tatgttgata atgtgaacct agagtgtata aatgtcaaaa gtatagataa
    59641 attaaatcta tattagtata tccaaaagta cccttaataa atttgtttaa ttgaattatt
    59701 atcgtttttt ctattaaatt taaatatttt ataaaaatag tattatttat aaaactagac
    59761 accctaaaat actacataaa taaaattaaa caaaaactaa aatggcaaat gtcattatct
    59821 aaagtgacat agaaacggtt tcttaaagtt gttactataa aatataaact ttataataaa
    59881 agtataacaa aagggaatca tatcgatata gaatataatt caaaaggagg caaaattatg
    59941 agtagttcta atcaatcgac aataaagaca tctatacagc gagtagggaa atttttaagt
    60001 ggcatggtaa tgccaaatat aggagctttt atagcatggg ggcttataac agcattattt
    60061 ataccaacag gatggatgcc taatgaaaaa ttgagtacta taggtgaccc aatgataaaa
    60121 taccttttac cactattgat agcttatact ggtggtaaag caatagcagg acaaagaggt
    60181 ggtgtaatag gtgcagcagc agctatggga gtaattgttg gggcagatat accaatgttt
    60241 atcggagcaa tgataatggg accatttgca ggatggataa ttaagaagtt tgataaattt
    60301 gtagatggaa aaataccaac aggatttgaa atgctagtaa acaacttttc aataggtata
    60361 ataggtatgc ttcttgcaat actaggattt tatgcaattg gaccagcaat agtagcaggt
    60421 acagctctta tagaatctgg agttcaattt atagttagca aaagtttatt accgttagtt
    60481 tcagtattta tagaacctgg aaaagtactg ttcttaaaca atgcaataaa tcatggtata
    60541 ttaggaccta taggtatagc tgaggcaaaa gaagcaggta aatctataat gttcttatta
    60601 gaaagtaacc ctggaccagg tttaggagtt ctattagcat attggatgtt tagtagagga
    60661 agtgtaaaac aatcagcacc aggagctgta ataatacatt tctttggtgg tatccatgaa
    60721 atttatttcc catatatttt aatgaatcca gttttaatat tggctacaat agcaggtgga
    60781 gcagcgggaa tactaacttt ctcaatatta ggagctggac ttgtagcagc accatcacca
    60841 ggaagtatat ttgcacttat ggcactagct ccaaagggag gattacttcc agtattagca
    60901 ggagttgcag tggcaacagt tgtatcattc ttagtggcag caccatttgt taagagagct
    60961 tcagcaaatc aaagtgaaga agacaatact tctttagaag aagctaaagc aaaagtgagt
    61021 gatatgaaat ctgtaagtaa gaactctaag aaagatattg aagaaaaaca gctggaagta
    61081 aatgaaatta agaagattgt atttgcatgt gatgcaggaa tggggtctag tgcaatggga
    61141 gcttctagat ttaaaaatag aataaaaaat ttagatttaa atatagaaat tacaaattca
    61201 tctgttgata atcttccaga tgatacacaa atagtagtaa ctcataatac attagttgaa
    61261 agagttgcta agaacaattc aagtgttgag atagtttcaa taaacaattt tttaaatgac
    61321 ccaaatttag atgtactatt taaaagacta gaatctaaat aaaataaaaa gtaccactaa
    61381 ttaggagtgg ataatttgaa aaaaaagaag attacatcta ggcaaaaaaa gataatacta
    61441 atgatagtag aaaattcaaa gaaaaatatt ccaataacta tttctgaaat tgcagggatg
    61501 ttggagttaa gttcaagaac tgtacttaga gatatgtctg gaattgaaaa atggtttgat
    61561 gaaaatgatt ttaactttgt aaaaaaacca ggagtaggat tgattttaga ggaaagtata
    61621 gaaaatcaaa attttataat tgaattatta gaagaagaaa aaatagaaaa agaatacagc
    61681 aaggaagaaa gaaatttaat catattatca aagctactag tttctaacga gccagtaaag
    61741 tcttattatt ttgcaaaaat attaaaggta tctgaagggg tattgaataa tgattttgct
    61801 ttagcaagta aatggctgga aagatttgat attgagcttg ttagaaaacc agggctgggt
    61861 gtttacttaa aaggtcaaga aaaaagcttt agagaagcat atgtaaatct tatatatgat
    61921 tcatttaatg aaaaagaaat actagatatg gtcagaaata taagtgaaaa tatacaaaca
    61981 gataaaacaa tagaaatttt aagtgaaaat agacttttaa atttaatgga taagtgcata
    62041 ataagaaaag ttgaaggtac attaacaaag aaactttcag atttagatgt aaatttagct
    62101 gatagtgcat atataggtct tgtagttcat atttcattgg ctttacagag gataaaaaat
    62161 ggtgaaaata taactatgga taaagaattt ctaaaagaat tatctataac agaagagttt
    62221 aaattagcta aagaaatcgt aaaaggtatg gaaatagatt ttagcatgga tataccacta
    62281 gatgaggttg gatatataac tatgcatata agaggtgcaa agcaaaggtc atcttcaaat
    62341 cacaatgctt taaacttaga tgatatagaa gtaatggata ttacaaataa gatgatagat
    62401 ttagctgaag atgaatttaa aataagttta aaaaatgacg agaggttatt taaagaccta
    62461 gcaaatcact taggaccttc tataaataga ttgaatatgg gattagaaat aagaaatcct
    62521 cttttagatg aaataaaaag caagtattca tatgtctata atggagttga aaagatttct
    62581 agaattataa aagataaact aagtataaat tcaatacctg aatcagaaat aggatatatt
    62641 gcaatgcact tcgcatcagc catagaaaaa aatcttatga tgtatgctaa tataaatatt
    62701 gttgtggcat gtcccactgg aataggtact tcaagattcc tatcaactaa gattgagaat
    62761 aaatttccta atttaaatat acttgaaacc atctcagcta taaacataga tgaagagtat
    62821 ttaaaggaaa aagatgttga tttaattgtg tctacagttg agttaaatac aagtttaaat
    62881 tatatatgtg taggtccatt tatgagttta gatgacgaac agttaatcaa ggaaaaaata
    62941 aaatctatag ctcaaaataa attaatcaat ttaaatgtaa aaaatggtac taaaaataag
    63001 aataaaatat atgcacagat aacagaaagt atgaatatag gaaaagatat tcttcaattt
    63061 ttagaggaaa ttaggtttga aaaatttgaa agtaaagatt taagtgagct tattgaagac
    63121 tcatcaaaaa tatttgcaaa atctagtgaa gatataatat ctataaaaga atctttaaaa
    63181 gaaagattaa aaatctcaat tccatatata gaagaatcaa aaattctatt attacattgt
    63241 attagtgaaa gaatagatat tatgaagtta tcaataataa agctagagaa tagaatcata
    63301 ctagattcaa atgaagaaat cgacaatgta gtttttatgt tacttcctaa aaattcacca
    63361 agttatcaaa gacaaataat gagtgaaata agtggttcat taatagataa tataattttt
    63421 acgaataaga taaataaatt ctctatagaa gagatgatat tagaggtaaa agatatagtt
    63481 tttaattttt atacgaacag attaaaagca tttatagata aataaaatta atattgaaaa
    63541 ggaaggttga tactatgaat aaagtattga atgagaataa tatattttta gggttagata
    63601 gtgtttcaaa ggaagaagct ataactttag caggaagaaa gttagttgaa aatggatatg
    63661 taaaagaaga atatatacca gcaatgctag aaagagaaaa agtaatgact acatatatgg
    63721 gaatgggagt tgctattcca catggtgtaa acgaagcaaa aaaagaaata ttatcttctg
    63781 gaatagttat attacaattc cctaatggta tagattttga tggtgaaaaa gcatatttat
    63841 taataggaat agctggtgtt ggagatgaac atttagaaat actatctaat atagcagtag
    63901 ttttagatga tgacttaaca gaaagactaa aaaattcaaa tgacaaacaa gcttttatgg
    63961 aagcttttgc caactaatct taggaggact ttaaaatgaa aaaggcaatt cagtttggag
    64021 caggaaatat tggaagaggt tttattggag gcttattagt taagtcgggt tatcatgtag
    64081 tatttgctga tgtaaatgag gagatattaa actcaataaa caaagataaa aaatatacta
    64141 tacacataag agatgtagaa tgtatagatg aagtaattga taatataagt gcggtttcat
    64201 ctataaaaga agaaataata gatgagattg tagaggctga aataataact acagcagttg
    64261 gacctttagt tttgactaaa atagcttcta caattgcaaa aggcataaag aatagaaaag
    64321 aaaagggatt aacaagtaat ctaaatataa tagcttgtga aaatgcaata tacgcaagct
    64381 cttctttaaa agaagaggta cttaagtatt taaataagga agaagtggaa tatttagaga
    64441 tgtacattgg ttttccaaat tgttcagttg atagaatagt tcctcctggt aaaaatgaaa
    64501 atcctcttga tgtaacagtt gaaaattttt atgaatggaa tgttgaaaag caaggattta
    64561 aaggagaaat accaactata gttggtatga atttagctga taatcttatg gcttatatag
    64621 aacgtaagtt gtttacacta aatacaggtc atgctataac agcgtatata ggatatttaa
    64681 aaggatataa gactatagaa gaaagtataa aagataaatt tatctatgac atagtaaaaa
    64741 gtgcaatggt agaaagcgga gaaggattaa ttaaaaaata caattttgac tcagaagcac
    64801 actataaata tattgataaa attttaaata gatttaaaaa tccatatctt aatgatgatg
    64861 tattaagagt tggaagggag ccattaagaa aattaagtga taaagataga ttgattaaac
    64921 ctttaatgac agcaaaatca tatgacctat cagttgacaa tttgattctt ggaataggtg
    64981 cagcgcttca ttataataat agtgaagatg ctcaaagtgt agagttacaa gagttgataa
    65041 agtctaatgg ggtaaaaaaa gctgttgcta aaatagcgaa tataaataat gatgaagaac
    65101 ttttaaataa tatcgaaaaa agttatatat ttatggaaaa tttataaatt tgcttgaaaa
    65161 aagttagttc tgataaagta agcataacat attattctac acagtttgaa ttatttgttg
    65221 aataatagag aattataata tataattaaa aagaataaat taatatattt acctgtatat
    65281 gtttgataat atggttcaaa tgtttctact aagctaccat taatagcttg actacaggag
    65341 tgaagaagat atagtttata cttattttaa attatatatt aagttaatta ctttgaattt
    65401 taagctcctg tctatgatat agacaggagt ttttttatta tcttaatata aaatacttac
    65461 aagaatagat agcaaagtta gagcaaatat aattttttta ttaatataac tttagaaagg
    65521 attgggtgga agtttaatga aggctttaca agaaaagata ttgagagaag gcagtgtttc
    65581 aggaaatgat atactaaaag ttgatagctt tttaaatcac caaattgatg tagctttttt
    65641 aaatgaaata ggaagagagt ttaaagagag atttgaagga gaaaaagttg ataagatatt
    65701 tacaatagag gcttcaggaa tagctatagc atcaattgtt tcacagtatt ttgataatgc
    65761 acctgtagta tttgcaaaaa aatcggaatc taaaaatttg gataaagatg tatatgaaac
    65821 taatgtatat tcatttacta aggcaagaga atattctgtt aaagtttcta aaaagtacat
    65881 aaacaaaggt gaaaatatac tgatagtgga tgatttcttg gcaaatggaa gagctgctct
    65941 tggacttaaa gatttaattg agcaagcaga ggctaactta gttggagtag gaattgtcat
    66001 tgaaaaagga ttccaagctg gaggagcact tttaaaggct aataatgtaa gattagagtc
    66061 tttggcagta gttgaatcta tagataatgg aactgtaaaa tttaggtaat ttatgatatt
    66121 atatacttgt gtttagcaca tattttaact atgtaattat ggaggatttt ttatgagatt
    66181 ttttatagac acagccaata ttgaggaaat aaaagaagca aatgatttag gtgtaatatg
    66241 tggtgtaact accaatccat ctctaatagc taaggaaggt agagatttta tagaagtagt
    66301 taaagaaata agtgaaatag tagatggacc aataagtgca gaagtaataa gtttagaaca
    66361 taaaggtatg atagaggaag cagaaaaatt atctaagata cataaaaata tagttataaa
    66421 gatacctatg acagcagaag gtctaaaagc agtgaaagta ctatcaagta aaggtataaa
    66481 gactaatgta acacttatat tctctgcggg acaagctctt ttagctgcta gagctggagc
    66541 tacatatgta agtccttttg ttggtagatt ggatgatata tcacaaaatg gtcttgattt
    66601 aattgaagaa atcgttgaca tatttagtgt aaatagcatt gaggctcaaa taatagtcgc
    66661 tagtgttaga aatccaatac atgttttaca agctgctaga atgggagcag atatagcaac
    66721 agttcctctt aaagttataa accaaatgat taagcatcct ttgacagaca aaggaataga
    66781 tagctttatg aaggattggg aaggtgcttc tttaaaattg taattataaa ttacgtttta
    66841 taagtatatt aaagaggtta ttatggaaat tctaagtaat aaggctaggc tattttgcct
    66901 agtcttattt tggtgtataa tatattgaaa catgttattg aaatagatta attttttaag
    66961 tgaggaggcg aaaaatggat aaaatattaa gagagataca aagagaagat aaaaaaaatc
    67021 catatactga ccaagaactt gctgaaatgt taaatgtagc taggtctgaa gtaatatcag
    67081 ttaggaaaaa aaataatatt ttagattcaa gagaaagaag aaaaaaaata ttaataaaag
    67141 atatatcaaa aattgtaagt gaaaatcctc aaatgtctga aagaaaaata actgaaatat
    67201 taatagaaaa tggatataat atatcgagaa gtgcagtgtc aaaattatta aaagaggaaa
    67261 atttaaatca gtcaaagagt gggattaaag ataaagacct agcatcatca ggaaagtatg
    67321 taaaggtgag taaagttgta gaagaagatg gatttgaaga attgataggt ataaagggaa
    67381 gcttgaaaga aaaggtaaat ctagctaagt cagcgataat gtatcctccc aatggccttc
    67441 atactataat atatggagaa acaggagtag gtaaaagtga attagctaca tgcatgtata
    67501 aatatgctat aaaaaacaac atcaaagaag agaacagtcc atttatagtg tttaactgtg
    67561 cagattatgc agaaaatcct aacctattga tagctcaact ctttggagta gtaaaaggtg
    67621 catatacagg agctgatgca aatagagagg gtcttgtaga acaagctaat aatggaatat
    67681 tgtttttaga tgaaattcat agattgcctg ctgctgggca agaaatctta ttttcattaa
    67741 tagatagagg agaatttaga agattaggag aaagtagttc taatagaaag gcaaatgttc
    67801 tcataataag cgctacaaca gaaaatccag attctaactt acttcaaaca tttagaagac
    67861 gtataccaat ggtaataaat ttacccaata tgagtgaaag accaaagtct gaaagatatg
    67921 aaataataat aaagtttttt gaaagagaag caaagcgagt aaacaagaat tttataataa
    67981 ctaaagaagt tatgtgtgca cttatgaatt ataagtgtac tggaaatata ggtcagttaa
    68041 aaagtgatat acaagtaact tgtgctagag cttttagtaa atcgatattt tctagcgata
    68101 aggtaattat agatttagat agtttaaggg attatataaa aagtggatat tatgattgta
    68161 attgtgaaaa tgaaaagtat tctgagtttt cagttgaaga tatatatata gatattagtg
    68221 aattggtgag tggaaaaaat agaattttat ccgataatga gataagtgag atatataatt
    68281 atgcagaaaa agagcttaag gttttggaaa gtaagtgctt ttcagaagaa gaattaaaaa
    68341 atgcatttat agaaaagtta gacaagaagt ttaatgctat taaaaacaat aaaaatttat
    68401 ctgatagaag aagtcaaata gactggggag gacaattaaa agagtctaca ttggagataa
    68461 tggataaggt aattgtattt atcaaggagc agtttaagca tgtaaatcaa ggcttgtatt
    68521 tggctctagc aattcacatt gagcatgcta taggaaggat aaaagatgga aaaactataa
    68581 taaatccgag tttagataaa ataaaagcat caatgccaat ggaatatgag ctatcgagat
    68641 atataatggg tatagttgaa gatttgacac aagtaacatt tccagaagat gagcttggat
    68701 atttggctta ttatataaat aaattttgtt ataatgagga aagtataaaa gataaagtta
    68761 aagtagtaat agttacgcat ggtaaagttg gaattgaaat gtctaaagtt gtaaaccata
    68821 ttttaggtat agaatgtaca ataggtatag aaatagcact tacagattca ccatcagagg
    68881 ggatagaaca tgtattagaa gagcttcaaa agatagaggc tcgaaaaggt attctagttc
    68941 taattgatat gggttctttg gtaattcttg gtgatgaagt tgaaaaaaga cttggaatta
    69001 gatgtaaaac tgtaaataga gtagatactt tactggcaat ggaagcagga aaacttgcaa
    69061 ctattgaagg aaaaagttta gatggtataa tagcagattt aaagaaaaat aagaattatg
    69121 ctatgataaa tacaaataaa tttagttaca gaaaaaacga gtatggaaag aaaaatgtaa
    69181 tcattacttt atgcttgagt ggtgtaggta cagctttaaa tttaaaagat catatagaaa
    69241 aacaaattaa ggaatatgat gcttcaattg aagtaaagcc aattgctttt ttaaataata
    69301 atttggaaga cgagttaaat gatattgaag ctgaatataa tattattgct atctgtggaa
    69361 ctattgatat agattataaa aacgtgcctt ttatttctta taatgaggtg cttggtaaaa
    69421 atggtattaa taaagtatta gagcatttaa atagtaaaca gccagcttta aatattgaaa
    69481 atcagttgaa taatttaata catgaagatt tgattttata caattttgaa ggaatttcaa
    69541 aggagtatat aattgatact cttgtttcaa agcttgaaga aggtggatat gttgattcaa
    69601 agtatatatt aagtgtatat aaaagagaag caatgggaag tgtcgtaatg gcctctaagg
    69661 tagctgtgcc acatggactt ccagaaaacg ttataaagcc tgcaatagca attgcaaggt
    69721 tgaataaacc tatagtatgg gacaataaat ttatggtgga tttggtggta ctattggcac
    69781 ttaaagaaaa taataagaaa gaaatacgaa gcttattttc aaaaattaat gaccagcata
    69841 ctttagaagt tttattaaat actgaagata aaaatgaaat aaaagaactt ttaagctaat
    69901 tattagtaca gagaagaaag acaaaaaatt tgctttagta taaaatttaa aactacttaa
    69961 ttgctaagta gttaattact cgagataagg ctagttctat gaaatttatt tatatgattt
    70021 tatagaatta gcttttttct tggtaaataa aatatatgaa tttatttatg caaaaagtaa
    70081 attttattgg acaattctat gaaaattttt ttctat
//
LOCUS       DAMKOJ010000006        69725 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000006 DAMKOJ010000000
VERSION     DAMKOJ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69725
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.006"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            231..476
                     /locus_tag="PC592_000493"
     CDS             231..476
                     /locus_tag="PC592_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF4054511.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGIKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            511..1236
                     /locus_tag="PC592_000494"
     CDS             511..1236
                     /locus_tag="PC592_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF4054512.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDVNPQLYGEETREETTFIYPEVDEFDLIAINI
                     ALGLQKPILGICRGLQILNVSLGGTLYQDNNLKEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDEKFVVGVQWHPE
                     MMVDYCNKMEKLFKYFINICSNL"
     gene            1259..2572
                     /locus_tag="PC592_000495"
     CDS             1259..2572
                     /locus_tag="PC592_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF4054513.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKAFGVASIFVY
                     MFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTTSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARVCFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            2778..3317
                     /locus_tag="PC592_000496"
     CDS             2778..3317
                     /locus_tag="PC592_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4054514.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQNIIDFYNEVGGETHFLSFGKD
                     EYKISLKEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            3406..5391
                     /locus_tag="PC592_000497"
     CDS             3406..5391
                     /locus_tag="PC592_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDF4054515.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKINDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTITLKGKTYKLKDTYLPTIDKKDPYKLTIEEKNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDRMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKKLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            5617..6585
                     /gene="spoIIIAA"
                     /locus_tag="PC592_000498"
     CDS             5617..6585
                     /gene="spoIIIAA"
                     /locus_tag="PC592_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HDF4054516.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKISNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMALDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKVIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIDD
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            6575..7096
                     /locus_tag="PC592_000499"
     CDS             6575..7096
                     /locus_tag="PC592_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HDF4054517.1"
                     /translation="MQIKIIIIALLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGRNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            7113..7310
                     /gene="spoIIIAC"
                     /locus_tag="PC592_000500"
     CDS             7113..7310
                     /gene="spoIIIAC"
                     /locus_tag="PC592_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HDF4054518.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            7326..7712
                     /gene="spoIIIAD"
                     /locus_tag="PC592_000501"
     CDS             7326..7712
                     /gene="spoIIIAD"
                     /locus_tag="PC592_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HDF4054519.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSVQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            7797..9002
                     /gene="spoIIIAE"
                     /locus_tag="PC592_000502"
     CDS             7797..9002
                     /gene="spoIIIAE"
                     /locus_tag="PC592_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HDF4054520.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSENKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLVGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTIYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            9061..9678
                     /locus_tag="PC592_000503"
     CDS             9061..9678
                     /locus_tag="PC592_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HDF4054521.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGSYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNNAKSNSSANEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLSLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            9690..10244
                     /locus_tag="PC592_000504"
     CDS             9690..10244
                     /locus_tag="PC592_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HDF4054522.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKNDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            10271..10957
                     /locus_tag="PC592_000505"
     CDS             10271..10957
                     /locus_tag="PC592_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HDF4054523.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSNNVDKQDGKESADIDIVDSKTSKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNNK"
     gene            11067..11429
                     /locus_tag="PC592_000506"
     CDS             11067..11429
                     /locus_tag="PC592_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF4054524.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            11514..12020
                     /gene="nusB"
                     /locus_tag="PC592_000507"
     CDS             11514..12020
                     /gene="nusB"
                     /locus_tag="PC592_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDF4054525.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDRVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            12004..13074
                     /locus_tag="PC592_000508"
     CDS             12004..13074
                     /locus_tag="PC592_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HDF4054526.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVMDNSK
                     GLRQSEAVFQHVNNLGILSDRIKSFKDRFHVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     RLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNRFISVHMSGGTTEILLTSKQDSHH
                     NVCDIDLSKFAKTSIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGVKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIIKDNGDNANQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVSEVVFAGGVSASKYIFRELTMKLGKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            13071..14276
                     /locus_tag="PC592_000509"
     CDS             13071..14276
                     /locus_tag="PC592_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDF4054527.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGIKVIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIRRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RLSKSLTNQIELDQYRLEAVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLRLE
                     DEKLVKIGALLHNLSPLATMDRGYSIAQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IEKIENKEV"
     gene            14278..14493
                     /gene="xseB"
                     /locus_tag="PC592_000510"
     CDS             14278..14493
                     /gene="xseB"
                     /locus_tag="PC592_000510"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDF4054528.1"
                     /translation="MNLTYEEAYKRLESILNELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            14496..15383
                     /locus_tag="PC592_000511"
     CDS             14496..15383
                     /locus_tag="PC592_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDF4054529.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDESKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLNGLAEYIIDREY"
     gene            15413..15850
                     /locus_tag="PC592_000512"
     CDS             15413..15850
                     /locus_tag="PC592_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HDF4054530.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGVVTALILM"
     gene            15884..17749
                     /locus_tag="PC592_000513"
     CDS             15884..17749
                     /locus_tag="PC592_000513"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDF4054531.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KESESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYINTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKDLIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSGKVKSMSTSVGEKLVDMANNNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     RELELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDNGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEDMLKVLLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNADELYDFVGLSPKSIADKIRKLFIK"
     gene            17882..18694
                     /locus_tag="PC592_000514"
     CDS             17882..18694
                     /locus_tag="PC592_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDF4054532.1"
                     /translation="MKKRIDLLLVEQGHFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCNIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEIVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNDGYEFDGEIYNNKIVEVVEASHNLEK"
     gene            18714..20393
                     /gene="recN"
                     /locus_tag="PC592_000515"
     CDS             18714..20393
                     /gene="recN"
                     /locus_tag="PC592_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDF4054533.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNTYLKKILEENDISIEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYRKIK
                     DRLDEILNRDERVEQLKSKLMKIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGLFTLDGVDDIEFMISFNLGEDINPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            20608..21474
                     /locus_tag="PC592_000516"
     CDS             20608..21474
                     /locus_tag="PC592_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054534.1"
                     /translation="MNKKDTLHLIFIIVIFILLWYVVVTVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDVDVQLSKLGENGKVFF
                     MYKEESNKWNETEMTKHGELSYVCEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFSSGIRDNREYFIEMVENSNLFNHESEKSKNKAYNNIRLEKVDIIVNEGKKD
                     TVYKAKLVESLDDGKTNNSNRNQVNYEASFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEN"
     gene            complement(21567..22058)
                     /locus_tag="PC592_000517"
     CDS             complement(21567..22058)
                     /locus_tag="PC592_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4054535.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKVLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKIGYTHMRLDTLPSMKSAQGLYKKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(22119..22559)
                     /locus_tag="PC592_000518"
     CDS             complement(22119..22559)
                     /locus_tag="PC592_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4054536.1"
                     /translation="MKLNVRIADINNWRDLVNLSVDKSQLDYIESNALSIAESKFITA
                     WIPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGRGYGKASLDFLVNHLKKEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            22720..23778
                     /locus_tag="PC592_000519"
     CDS             22720..23778
                     /locus_tag="PC592_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF4054537.1"
                     /translation="MNKINKNFKKIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNQDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNRYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            23920..24744
                     /gene="spo0A"
                     /locus_tag="PC592_000520"
     CDS             23920..24744
                     /gene="spo0A"
                     /locus_tag="PC592_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HDF4054538.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            25156..26277
                     /locus_tag="PC592_000521"
     CDS             25156..26277
                     /locus_tag="PC592_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054539.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSYQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            26295..27170
                     /locus_tag="PC592_000522"
     CDS             26295..27170
                     /locus_tag="PC592_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HDF4054540.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLANVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIVLKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNSLGNTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            27194..27886
                     /locus_tag="PC592_000523"
     CDS             27194..27886
                     /locus_tag="PC592_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4054541.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDINQINEIIVVDDGSIDN
                     TAKAVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADVIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            27894..28718
                     /locus_tag="PC592_000524"
     CDS             27894..28718
                     /locus_tag="PC592_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF4054542.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            28723..29790
                     /locus_tag="PC592_000525"
     CDS             28723..29790
                     /locus_tag="PC592_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HDF4054543.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPNISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFVASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADVVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLNKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            29792..30328
                     /locus_tag="PC592_000526"
     CDS             29792..30328
                     /locus_tag="PC592_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF4054544.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     VKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVHEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            30396..31001
                     /locus_tag="PC592_000527"
     CDS             30396..31001
                     /locus_tag="PC592_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDF4054545.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPSSSNN
                     ILNNINPAVEYYNLNISIKDAVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILTLISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTVSIGIIKFLAK"
     gene            31013..31927
                     /locus_tag="PC592_000528"
     CDS             31013..31927
                     /locus_tag="PC592_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4054546.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLI
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKSQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDIELQKAEAK"
     gene            31969..33141
                     /locus_tag="PC592_000529"
     CDS             31969..33141
                     /locus_tag="PC592_000529"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDF4054547.1"
                     /translation="MSRVIWIVIDSVGIGALPDAENFGDSKDVSTLGNIFREYPDINI
                     PNMRKLGIGNIDGVDFFESIKTPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIDEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKKDLF"
     gene            33188..34000
                     /locus_tag="PC592_000530"
     CDS             33188..34000
                     /locus_tag="PC592_000530"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDF4054548.1"
                     /translation="MFEKIAQSSKFINAKINIKPKIGLILGSGLGDLANDIEDSVTIK
                     YSEIPNFPISTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEVLIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRLGDRFPDMSDAYSS
                     RYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQSLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            34203..35528
                     /locus_tag="PC592_000531"
     CDS             34203..35528
                     /locus_tag="PC592_000531"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDF4054549.1"
                     /translation="MRMYDIIRKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFINSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLIASSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFDLA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAYDFDDGVEKIRESIKSGDAIHKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYINKIKAEDVGVSAMILGAGRETKDDVLDLSVGIILEKKVGDYINEGE
                     VLAYMYYNDEQKLSLAKDRFIDSYSIVDSKVEKNKLIYGIVTKEGIKKF"
     gene            35741..36820
                     /gene="mltG"
                     /locus_tag="PC592_000532"
     CDS             35741..36820
                     /gene="mltG"
                     /locus_tag="PC592_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDF4054550.1"
                     /translation="MNFKENRLKIAALIIVILIILAGIFVSMQIGPYNKNNKKDVIID
                     IPNGASIGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKKLNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPDKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            36992..37666
                     /locus_tag="PC592_000533"
     CDS             36992..37666
                     /locus_tag="PC592_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDF4054551.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKIQKPKRVLEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFENNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLIPIGDGVALSYKESKRG
                     DVDGIK"
     gene            37653..38900
                     /locus_tag="PC592_000534"
     CDS             37653..38900
                     /locus_tag="PC592_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF4054552.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YKDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEAMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            38972..40636
                     /locus_tag="PC592_000535"
     CDS             38972..40636
                     /locus_tag="PC592_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDF4054553.1"
                     /translation="MSKKKTPFLKKVGKRSWCVFTIILIIYSALIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKYQVLVVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQAKNIDKNMKKELEKNGIMIEEKTMRYSKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTID
                     NKDKDRHLKTTIDYNIQRKLEQILNKEENPTAAIISEVSTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIMANNGTFKPLYLYKSLVDNDMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIQ"
     gene            complement(40734..41018)
                     /locus_tag="PC592_000536"
     CDS             complement(40734..41018)
                     /locus_tag="PC592_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4054554.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(41044..42558)
                     /locus_tag="PC592_000537"
     CDS             complement(41044..42558)
                     /locus_tag="PC592_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054555.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQSLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADIVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHNYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKTSDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELSKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNAKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHED"
     gene            42740..43552
                     /locus_tag="PC592_000538"
     CDS             42740..43552
                     /locus_tag="PC592_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054556.1"
                     /translation="MCNFKKILGLFMIIMLSVSMVACSSGGDSKDESKGKDKQFIEDL
                     GKGLKKRWDLASKEEAGTLNLEQNEAYEKFVEVEMDAVSKYKDAEFDSPELGKLAKDY
                     IKALEDSKEAIKYYSNDQLKFSELWEKPYNERSTILLTLVDKFGLKVDEKEFKVLKDN
                     AQIVNEENDLKEKVNAMAKGIKFEKVKDEYDWKTYQATVENTSDLDLQDFYLDINLID
                     KDGVIIETQTSTSVNGTWKKGQKVRLEFSTDKDFEKIEWTPHYSANNYSITE"
     gene            43592..45037
                     /locus_tag="PC592_000539"
     CDS             43592..45037
                     /locus_tag="PC592_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4054557.1"
                     /translation="MKIKKLLTIGLSLSMFIASCHISANALDKIESIKGADKYETTGI
                     IADKQNYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVREKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVNDTNSTR
                     LGGTDRYDTNKKIINKFYGGVKEFYIASGTDLVYALVGSTVAKNNAIVLVNNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGRQYTVEDAANAVKKLLGVKKFYYN
                     ENYPEDEDVIFLLDENFEFSGKQFYAFGYVTENSEGDVRYCVEKNDMSKVYTYNVSGV
                     MQVCNPDDYKKKEMISEEKAKQLALEECARKHKVGVDLLKVNIAYIDDFDDIKVYAVR
                     IDSKPHPNQTYGWYFIDVYSGYAYKDVWNNI"
     gene            45175..45333
                     /locus_tag="PC592_000540"
     CDS             45175..45333
                     /locus_tag="PC592_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054558.1"
                     /translation="MDNFLLSILASILASYIVYLISKLFRKRKKPLKAGTKSGWELDF
                     KIKFHKFK"
     repeat_region   45620..46246
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45620..45648
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(46324..46458)
                     /locus_tag="PC592_000541"
     CDS             complement(46324..46458)
                     /locus_tag="PC592_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054559.1"
                     /translation="MFEKTNINTSVMNIIESDERPIRDDELIIFAKIFGVSINYILGL
                     "
     gene            46637..46888
                     /locus_tag="PC592_000542"
     CDS             46637..46888
                     /locus_tag="PC592_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054560.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(47053..47241)
                     /locus_tag="PC592_000543"
     CDS             complement(47053..47241)
                     /locus_tag="PC592_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054561.1"
                     /translation="MIGFKKRDTKYLLKIVARAHGISVAEAIVEMQTTINNARNNPDP
                     EKQAEFIISLNTIFTKNL"
     gene            complement(47699..48358)
                     /locus_tag="PC592_000544"
     CDS             complement(47699..48358)
                     /locus_tag="PC592_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4386 family protein"
                     /protein_id="HDF4054562.1"
                     /translation="MNIVVGVLSILSAFCIAGSMIGLMFSFGYPKIIRENPIIILKRM
                     QNKKTMISLLFYLFGIGGFMVVQASIALRFIEQSKGEFIWSNFAYINGIIYGVLLFVG
                     ILRYTKTFPMLSNQMINKQITEKEAGQLYKVLNTYIGETMTEHVAFVFLSFMIFCNSM
                     SLLSINYVANWIGLLGIIIAIGLFIGNLEFLGIKKLFIVNRVFSSLSAFWLLLLGICI
                     I"
     gene            complement(48414..48851)
                     /locus_tag="PC592_000545"
     CDS             complement(48414..48851)
                     /locus_tag="PC592_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF4054563.1"
                     /translation="MEEHEIFNTFVQILNWASERNKNSKSYGTDDKLYIAEIHTLVMI
                     GKMPGILQKELCKEVGVTKGRMSVIIAHLQEKNLIEMRREQGNGCTIPIYLTTLGEQI
                     YHNHNEQEMNMKIQIYQVLSKCSQEEIEKFNGILRDILEILRQ"
     gene            complement(49175..49339)
                     /locus_tag="PC592_000546"
     CDS             complement(49175..49339)
                     /locus_tag="PC592_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF4054564.1"
                     /translation="MFFHSTYNNGSYISHIGIYIGNNHMYHVNNPIGYADLTSAYLQQ
                     HLIGAGRIKQ"
     gene            49875..50384
                     /gene="vanZ1"
                     /locus_tag="PC592_000547"
     CDS             49875..50384
                     /gene="vanZ1"
                     /locus_tag="PC592_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HDF4054565.1"
                     /translation="MKSKKYNITKGLFIVYIIILTWIILFKLQFDVSSIETMNLRSIN
                     LVPFAGSLIINNKVDISEIILNVAIFIPFGIYICMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINILAFIVTIIVVLF
                     LGLVIFANL"
     gene            complement(50493..50687)
                     /locus_tag="PC592_000548"
     CDS             complement(50493..50687)
                     /locus_tag="PC592_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDF4054566.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(51180..51596)
                     /locus_tag="PC592_000549"
     CDS             complement(51180..51596)
                     /locus_tag="PC592_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4054567.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEIHTTFYMLFSTIIYI"
     gene            52163..52525
                     /locus_tag="PC592_000550"
     CDS             52163..52525
                     /locus_tag="PC592_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054568.1"
                     /translation="MKIRKRGFISIECVISIAILYVAVYLVSTSLYSCYSFVSRNISD
                     RKMLSTAKKYIEDEKYRIQNSKYELIENKIEKNYINGYEISSRVEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            52509..53228
                     /locus_tag="PC592_000551"
     CDS             52509..53228
                     /locus_tag="PC592_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054569.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFKLGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDISNSEGEFREYFLGNNMIECIKKIKDTSYSS
                     VEGLSLKVENNTIYDREDFFEFDIESSVREKEFLKTIKVRVKIKNPWVGIDIEDYMNK
                     SNNNKIYDKKFNNYKASENNEILNQFKNESENISNQEVVEPTEEDNEEYEEELKQNII
                     ENIKKNFDEKKLVQVYKYRGV"
     gene            53248..53667
                     /locus_tag="PC592_000552"
     CDS             53248..53667
                     /locus_tag="PC592_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054570.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNIENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIILPKNVKIARSIETIKFKSDG
                     SPQKASTIEIYNNRLRKIITITPVSGRVLLKEGKYET"
     gene            53657..54187
                     /locus_tag="PC592_000553"
     CDS             53657..54187
                     /locus_tag="PC592_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054571.1"
                     /translation="MKHKYGYLLLESVVSLSSMLIMILVLYSIFLSTISLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIINVSNYEDTFKKATSIKCRYVDENVNNNEESISNK
                     EIILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSINNNGQYVNIKLKLSKRSQK
                     YETEFKIKVWNFSENI"
     gene            54500..55057
                     /gene="efp"
                     /locus_tag="PC592_000554"
     CDS             54500..55057
                     /gene="efp"
                     /locus_tag="PC592_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDF4054572.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYDQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            55149..55604
                     /locus_tag="PC592_000555"
     CDS             55149..55604
                     /locus_tag="PC592_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF4054573.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFAEAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            55766..56476
                     /locus_tag="PC592_000556"
     CDS             55766..56476
                     /locus_tag="PC592_000556"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDF4054574.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGV
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINEDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            56530..57600
                     /locus_tag="PC592_000557"
     CDS             56530..57600
                     /locus_tag="PC592_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4054575.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPTDTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYSPFTLEESVN
                     IVKKVLALFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKLGVILKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            57628..61182
                     /gene="smc"
                     /locus_tag="PC592_000558"
     CDS             57628..61182
                     /gene="smc"
                     /locus_tag="PC592_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDF4054576.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDIYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKILEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELENNKLSSSGELSALQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNVRDENINLEITELNKNIDIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSTNLQDSISEHSKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KINNIKHEISQLELKRESLDKDIKNIKSEIDSHESKIKDLEKSIIIKSTSIENIESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKRDNVRKDIEELDNLYNQNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEAYNSIVRDIKRISGENYELEEKNKQLEESLNYEE
                     QEIIKLQDSIATEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRNLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAKEITDII"
     gene            61209..62480
                     /gene="ftsY"
                     /locus_tag="PC592_000559"
     CDS             61209..62480
                     /gene="ftsY"
                     /locus_tag="PC592_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDF4054577.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDEEEVVDSVDSLENLEETIFSGLEE
                     EVIDKDEDIEEKTEESVNNEGTEEIENFEKIDVEMDSDGKEVENISDNDSQEEIIEEL
                     ENYDEIESKEIEAKEEKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELLEDL
                     EEILITADVGVNTTMDIIERLRDKIKQKGIIEPIKVREELKSIVEDILTNENSTLDIE
                     PAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWANRTN
                     VDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKIVDR
                     EFPEAKREVLLVVDATTGQNAVIQAKTFKEVADITGIVLTKLDGTAKGGVVLAVKSEV
                     DVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            62583..62951
                     /locus_tag="PC592_000560"
     CDS             62583..62951
                     /locus_tag="PC592_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDF4054578.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            62948..64300
                     /gene="ffh"
                     /locus_tag="PC592_000561"
     CDS             62948..64300
                     /gene="ffh"
                     /locus_tag="PC592_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDF4054579.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEADVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIARGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            64338..64610
                     /gene="rpsP"
                     /locus_tag="PC592_000562"
     CDS             64338..64610
                     /gene="rpsP"
                     /locus_tag="PC592_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDF4054580.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            64675..64902
                     /locus_tag="PC592_000563"
     CDS             64675..64902
                     /locus_tag="PC592_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDF4054581.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            65010..65525
                     /gene="rimM"
                     /locus_tag="PC592_000564"
     CDS             65010..65525
                     /gene="rimM"
                     /locus_tag="PC592_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HDF4054582.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLSVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGIEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            65534..66229
                     /gene="trmD"
                     /locus_tag="PC592_000565"
     CDS             65534..66229
                     /gene="trmD"
                     /locus_tag="PC592_000565"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDF4054583.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSIAKH
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            66403..66753
                     /gene="rplS"
                     /locus_tag="PC592_000566"
     CDS             66403..66753
                     /gene="rplS"
                     /locus_tag="PC592_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDF4054584.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            67075..67971
                     /gene="ylqF"
                     /locus_tag="PC592_000567"
     CDS             67075..67971
                     /gene="ylqF"
                     /locus_tag="PC592_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDF4054585.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADKDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALKLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEIPENVKR"
     gene            68360..69652
                     /gene="brnQ"
                     /locus_tag="PC592_000568"
     CDS             68360..69652
                     /gene="brnQ"
                     /locus_tag="PC592_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF4054586.1"
                     /translation="MGKTKDIIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIKPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKVI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLHSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT        28143 a         7165 c        12450 g        21967 t
ORIGIN      
        1 aatattaata ggtttttaaa ataggattag ataggtaata ggttaagtta aaataaccca
       61 ttacctattt ttatttgtag gaaaagtgtc tatgaaatta aaagtaaaaa ataccactaa
      121 taaaacgatt gaaaacacta gataaataat aaataaaaat aattataaat tttggcacat
      181 atattgctaa tcatagaaat aagatgacaa aataataggg aggtttaata atgaaataca
      241 aaacaacagg gacttgtgct acagaaattg aatttgaggt aaaagaaaat aaagttacaa
      301 atgtaaactt tataggtgga tgtgatggaa atttaaaagg gataaaagta ttagttgaag
      361 gcatgaatat agaagatgta atacaaaaat taaaaggaat agagtgtaaa acaaagccaa
      421 cgtcttgtcc agaccaactg tctctagcat tggaaaatta tatgaatata aaataataca
      481 taaaacaatc gattagttag gagtttaatt atgaaaccaa taatagggat tttaggaaat
      541 ttaataataa tggaaaatgg tatgtttcca ggtcttgaaa ggtcatatgt aaataatgat
      601 tatataaatg cagtactaaa aggtggaggt agtccagtaa tcattcctgt aaatacagat
      661 aaagaagtta taaaaaaaca gattgaaatg gttgatggag tcttaatatc tggaggatgg
      721 gatgttaatc ctcaactgta tggagaagaa acaagagaag aaacaacatt tatatatcca
      781 gaagtggatg aatttgattt aattgcaata aatatagcat tagggcttca aaaacctata
      841 ttaggtatat gtaggggact acaaatttta aatgtaagtt taggaggaac tttatatcaa
      901 gataataatc ttaaagaagg aagttatata aaacacacac aatcttccaa aagacatgta
      961 gctactcata aagttgatgt taaagaagga agtattttag aaggaatatt gggaaaacaa
     1021 ttacttacaa atagttatca tcatcaaagt gtcaaccagc ttggaaaagg attaaaagcc
     1081 atagcatact caaaagatgg tataatagaa gctattgaga aagaggatga aaaatttgta
     1141 gtaggagtac agtggcatcc agaaatgatg gtagactact gtaataaaat ggaaaaacta
     1201 tttaaatatt ttataaatat ttgttcaaat ttataatata ccttggaggg gattgaacat
     1261 gaacgaaaag aataaaatgg gattgataag tattatactt ttaggcatta atgcagtagt
     1321 aggagctgga gtttttctat taccaggaga tgcaatgaag gcatttggtg tagcaagtat
     1381 atttgtatat atgtttgata tgttattagt tttatctatg gcattctgtt ttgctgaggt
     1441 tgcaggtaaa ttcaataaaa atggtgctgc ctatgtatat accaaagaag cttttggaga
     1501 tttttgtggt tttgaagtag gtcttatgaa atgggtaata ggatgtatct cttggggagc
     1561 tttaatagta ggttttccta catccttatc agcagtatgg gctccagcag gtgaaccaca
     1621 tatacaaaaa attataattg tagccatgat agttggactt acaattataa atttattagg
     1681 tgtatctcta tcaaaaattg tacaaaatgt tataactgta ggtaagctaa ttccattaat
     1741 attatttata ggaataggta tattttttat aaaaggagtt aattttacta cttcaacaat
     1801 ggtgcctcca ggagctggag ctacagagtt tggagcagca gcacttttaa tgttttattc
     1861 atttacagga tttgaatcta tagcagttgc agcagaagat atggaaaatc cacaaaaaaa
     1921 tataccaata gcaattataa gtgtaatagt aattgcatca ataatatata tattaaatca
     1981 agttgtatgt gttggtatac taggagattc attatctagt acatctacac cagtggcaga
     2041 cgctgcaaga gtatgctttg gaaatatggg agctggactg gttacatttg gaacattggt
     2101 ttctgttggt ggaatttgta tgtgtggcgc ttttgtaaat ccaagaagtt gtgtagcttt
     2161 agctgatgat aaaatgttac cgagaatatt tgcaagaaaa gataaaaaag gtacaccata
     2221 tgtagcaata atagctacta tgttaattac tatcccaata gctctatctg gaagttttgc
     2281 tgaattagca gcaataagtg cagttgctag atttatacaa tatataccaa catctttatc
     2341 agtattagtg tttagaaaga aaagaccaga attagtaggt acttttaaaa ctccttttgg
     2401 agcagtgatt cctctaattg ctgtatgtgt tggaacatgg ttattattcc aagcatctat
     2461 gcatcaatta attatgggat taggagcttt ggcaattgga gtaccattat actttataat
     2521 gaagtcttat aatagaaaag tttatggtga aaatttaaag aaaatagttt aattatgtta
     2581 taacagttta ttgatttaaa gttagatatt ggcagaaaat taaatacaaa taagtatcta
     2641 taaggctata ttaaaatatt attgattttt tattttaata tagccttata ttgttaatca
     2701 gtaagtgaaa aatattgtaa caacaaaaga acaatagtat tatgtttata gacaaaaact
     2761 tattaggagg taaagttatg ccaacaataa cattaaaaaa tggtgtagat gtacttatta
     2821 gagaaggagt aagagaagat gctcaaaaca ttatagattt ttataatgaa gttggtggag
     2881 aaactcattt tctgtcattt ggaaaggatg aatataaaat atctttgaaa gaacaagaaa
     2941 atgctataga atcagcaaaa gcatctgata attcggttaa actgattgca tttatagatg
     3001 gtgaaatagt tggtattgct acaattgatt ctaatcaaaa ggcaaaagga aagcatgttg
     3061 gagtattagg aattgttgta aaggaaaaat attggggaat tggactgggt aaaaggctta
     3121 tgttagacct tatagaatgg tgtaaatcaa atggaataac caagaagata actcttgtca
     3181 ctaatgaaga aaattataat gctataggat tatacaaaaa agttggattt gaagtagaaa
     3241 gcatactaaa gaaagaatgt tattataatg gtgtttacac tgatttaata ggaatgtcac
     3301 ttttgttggg aatataatta gtgtacattt tatatcgaaa aaactatatt aagtatggta
     3361 taattaaaaa agaatataac ttaatataat tttggaggac gaattatgaa aaatctgtgt
     3421 aaaatatcag atgattattt aaacagcaag cttaagtatt taaagttatt atcaaaacaa
     3481 tatccaagta tatcaaaagc aagtacagaa ataataaatt tagaggctat attaaatctt
     3541 ccaaagggaa cagagcattt tataacagat gtacatggtg aatatgaacc atttgtacat
     3601 gtattaaaaa atggttctgg tgtaataaag agaaaaatag aagaattgtt ttcaaataca
     3661 ataagagaca gcgaaaaaaa aatgttagca actcttgtat attatcctga acaaaagtta
     3721 gacctaataa ttaagcaaga ggaaaatata gatgattttt atagaataaa tatttatagg
     3781 cttatagaac tttgtaaata tgcttctagc aaatatacta ggtctaaagt cagaaaactg
     3841 ttaccagaaa attttaaata cataatagaa gaacttttgc atgagcatgt taaaagtgaa
     3901 cataaagaag agtactataa aagtatagtt gaaacaatag ttgatatagg aatagctaaa
     3961 gagtttataa ttgctatttc tacagttata caaaaattag ttgtagatag acttcatgta
     4021 ataggagata tttatgatag aggtccaaga ccagatataa ttgtcgataa gcttattgaa
     4081 catcattgtg tggacattca atggggaaat catgatatct tatggatggg tgcagcatca
     4141 ggtgaaaaaa cttgtatagc aaatgcactt aggatatcag ctagatatgc aaatttagac
     4201 attgtagaag acatatatgg aataaatcta ttgcctttag ccacttttgc gatagagatg
     4261 tataaagatg acccttgtaa agaatttatt ccaaagatta atgaccaaag tgtaacaaca
     4321 acagaaaagt ctttaatggc aaaaatgcac aaagcaataa gtataattca atttaagctt
     4381 gaaggtgaag ttataagacg aagacctgag tttgagatgg aacatagact tttacttaat
     4441 atgataaact atgatgaagg tacgattact ttaaaaggaa aaacatataa attaaaagat
     4501 acttatttgc ctacaataga caaaaaagac ccatataaat taactataga agaaaaaaat
     4561 gttattgata aattagtatc ttcatttaga ggaagtgaaa aattacaaaa acatgtttca
     4621 tttctgttct ctaaaggaag tatatattta aaagctaact caaatttact gattcatgga
     4681 tgcgtaccat taaatgaaga tggaagcttt atgtctatga atataatggg caaagagtat
     4741 aaaggtaaag cccttatgga tagaatggag tctctagcaa gagaaggatt tttctttaaa
     4801 gataaggcag aagaaaaact gtatggcatg gatattatgt ggtatttatg gactgggaaa
     4861 tgttcatcat tatttggtaa agatgatatg actacatttg aaagatactt tatagcggaa
     4921 aaagagactc ataaagaaaa taagaatcca tattttaaac ttagagaaaa tgagatggct
     4981 tgtaaaaaat tatttgaaga atttgattta gaacttgatg aatctcatat aataaatggt
     5041 catgttcctg tagagagtaa aaatggagag agcccaataa aagctaatgg taaaattctc
     5101 gttatagatg gtggtttttc tagagcttac caaaaaacta ctggtatagc tggatacact
     5161 ttgatataca attctagaac tttgcaatta gtatcgcatg aaccatttaa ttctgctgaa
     5221 gaagccattg caaatgaaag tgatatctta tcaacaactg ttgtagtgga acataaggca
     5281 aagagaaaaa tggtgagaga tactgatgaa ggagtaaaaa tacaagagga aatagaagat
     5341 ttaaaactac ttttaatggc ttataagaaa gggctaataa aagaaatgta gatactatag
     5401 aggcacttca taattgaagt gtctttttgt taatacttat taaatatatt atatagatta
     5461 ataatagtaa tttataacct tatacttact aagtgaatcc aagataaatg ggttcacttt
     5521 ttttatttat aaacattata aaaaaatata gatgttttgg ttatattcct tgtcctttat
     5581 aaatagaatt atataaacaa aggaggagga caagaaatga ataaactttc tgatgaaata
     5641 ataaactctc tttctacaac tataagagaa aaggtagaaa aaatctcaaa caataatcta
     5701 aacatagaag aaattaggtt acgctcacaa aaaccattga tactaaatgc aaactctaaa
     5761 gattattttt acaatcaaaa aactatggca ctcgatttaa atcaacaaaa ctcatatgta
     5821 gtaacaagag aagatgtaga gcaaactttt caaataatat gtaaatattc aatacattca
     5881 tttatggatg acataaaaaa aggatttata actttgagag gaggtcatag agtaggatta
     5941 gttgggaaag taatagtaga agatggacaa gtcaaaaata taaagcatat atcatcttta
     6001 aatataaggg tatcaagaga aattattgga tgctctgata aaattttaag tcatatcata
     6061 aagggaaaaa atcagattaa taatactttg ataatatcac cacctcaatg tggaaaaaca
     6121 actttaataa gagatatagt aagaaattta agtaatggta atgaagatta tggatttaaa
     6181 ggtttaaaag tagctttagt agatgagcgt aatgagatag caggagctta tctaggtgtt
     6241 ccacaaatgg atgttggaat aaggactgat ataatagaaa cttgcccaaa agacttgggt
     6301 attacgatgc ttttaaggtc tatgtcacca aatgttattg tgacagatga aattggaagt
     6361 gaaaaagaaa taaaggcatt atacacagca ttaaatggag gtataggatt aataactact
     6421 gtgcatggag attcaataga tgatatacaa aatagaaaag aattaaatag acttctggat
     6481 aaagagttat ttaaaaaagt tataattctt tccgcaaaaa gaggagcagg aacgattgaa
     6541 aaaatttatg atttagaaga aaagagatgg tattttgcaa attaaaataa ttattatagc
     6601 tctcttgata ggaagtagtt atttgatagg tgaacaaata tacaaaactt atactcgtag
     6661 acataaacaa ttgaacgatt taataagagt tttagaaatt ttgaggatgg atttatcttt
     6721 cggactttat acattggaag aaatctttaa tagaataggt agaaataaag agttttgttt
     6781 ttggaaattt ttctatcaaa tatcagaagg acttcacaat gaacaaagta aaactttgga
     6841 aataataata tcagagaata ttgatgtctt aagcaaagaa acttatctag gcaataaaga
     6901 aattgaggaa ctgaaaaatc taatacttac tttagggaaa agcgatatag agtcacaaca
     6961 aagaatgata gatttatcta tagaaaattt gaaaaaacaa acctatgaga caaaggaaga
     7021 tataaacaaa aaaggcgtat tgtataaaaa attagtgaca tttataggta taggtatatg
     7081 tattatattg atttaatatg gggaggttca ttatggaaat atcattgata ttaaaagttg
     7141 caggtgtcgg tattctaata tcagtattga atatgatatt ggaaaaaaca gatagaaaag
     7201 attgggcagg tcttactaca ttagcaggtg taataatcgt attgggtatg gtaataacag
     7261 aaataagtga tttgtttaat actgtaagaa caatgtttca actttactaa agaggaggga
     7321 gtaatttgga aataatgcaa ttaataggaa ttgcaatcat ttcaactaca ctctgtttag
     7381 taattaaaaa agatagacca gagatagcaa atttcatagc aataataact ggagtaataa
     7441 tactattgtc agttatgttt aagctaaatt ttatagtaga tagtgtacaa gatttggcta
     7501 acaaggctaa catcccaact atgtatatat cattaataat aaaattaatt gggatagcat
     7561 acctaatgga atttgcgata caactttgta aagattgtgg ggaaggaaac attgcttcaa
     7621 aactagaatt tggaggtaaa ataatagtta tgtcaatgtc tttccctata cttttgtcca
     7681 ttgtagaaat ggtggtgaat ataattccat agatgtgtat cttggaatga ctataagtat
     7741 attatagagc tttcgttgta ttgaggttta tagagtgaag agaggcatgg ttgcttatga
     7801 aaaaaagatt tttaccaatg attataggtt ttttatttac tttctttttt gtaaatatct
     7861 ttgctattat gatatttgct aatgaagtgc caagtagtga aaataaagaa tatggtgaaa
     7921 caaaaaatag catagataaa tatatagatg gtcaattaga caagctggat ataaatgaaa
     7981 ttcaagacta tataaataaa gaaatagtta ttaatgatgt taatttaaaa tcatttgtaa
     8041 aagatttaat tagtggagaa aaaaatatct tagatttatt caataaagat ggtttgaaga
     8101 tattgatgtt tgatgaattt aaagcaagtt taaaggtagt agcagtgatt ttggtattgg
     8161 ctctgttatc atccatttta aagagtctgg aaaattcttt ttcatcaggt gcagtaagtc
     8221 aaatagcaac atatataata tttatcacaa tggtatcact tacacttgtt ggttttaaag
     8281 atgtattgca gatttgctat gatgcaatag accatactgt aggtcttatg caagttataa
     8341 tgccaatttt aataacattt ttacttttaa ttggattccc aataacgtcg actactttga
     8401 atcctatttt cataggagga gtaacattca taaatgtatt ttttaaaaat tttctatttg
     8461 tatctattac tgttgcattt ggaattttaa taataaataa tttatcaaaa aatataaggc
     8521 taaagagatt tttctccttt gtaaaacaaa taaattatgt ttctattgga gcaatgttta
     8581 ctatttactt aggtcttgta tctatacaag gattgtatgt aaccagtttt gataaattca
     8641 gtgtaaaaac tgctaaattt gctataggta attttattcc tgttgtcggg ggatttgtat
     8701 ccgattctgt agatatttta ttatcttcat ctcagcttat aaaaaatata tttggaggaa
     8761 tagggcttat attacttgtt ggaatttgtt tacttccagt gataaaaatt ttatcagtaa
     8821 tagtagtata caaattagca gcaataattg tagaacctgt tggagaggat ggaatatcta
     8881 attttttaaa tgaagtggca aatttaatga taataatgct agcatcagta attgctataa
     8941 cagtaatgtt ctttgtaact gtagctatct tgacctcgat aagtgtcgta agtcaaggat
     9001 aatttatata tcaattaaaa ataattcatt taatctaaag tttttagaga ggaggatgct
     9061 atgttagagg gcataaaggc gtggatagtt agtgttttga taggagcatt tatagtaaat
     9121 atagtagata tgattttacc aagttctaag ataaaacctt atgtaaacct agttttaaat
     9181 tttatgtttg tatttattgt aataactcca gtggtaggat ttttttcaaa agatatgagt
     9241 ttagaagata gaatattgaa atctatggga agctacaaca aacagtatgt agatagtaca
     9301 aatgctttag caaaagagac tggaaataat agtctatcta agggatatga ggatgggtta
     9361 aaagaagtac ttaaattaaa acttgatgaa tatggttatg atttagaaga tatagagctt
     9421 aatggagcaa atataaataa tataaaaata aaagaaaaga acaataatgc aaaaagtaat
     9481 agcagtgcca atgaagaaaa taaaaataat agtactaaaa gagaggaaga aaacataaac
     9541 tctaatgaca aagaaaattc taaacaagtc ttcaaaaaag gtacagagta tgggttgagc
     9601 ctaaatgaag aaaaattaaa aaatgactta ataaaggtgc tggatgtttc tatagaagat
     9661 atacaaattg ataaatagga gttgggagaa tgttgaaaaa cttaaatgac aaagataaga
     9721 gaaaggtata ttcactaata actatagcag gaatatgtgt ggtttcatta gtattattat
     9781 cttgttttcc tagtagcaaa aatgataaac aagttggaaa aacagagacc aataaaaatg
     9841 ctgaaaagca agtcactaaa gaacaagaaa aagatgattt agaatcaaaa ttaacagcaa
     9901 tactatctaa aattgatgga gcaggagatg ttgatgtaat ggttacattt gaatcaagtg
     9961 aagaaataca acctgctttt aattcaaata atacaacaga aacaacagag gaaaaagatg
    10021 cacaaggtgg agaaagaaca gttacgactt ctagtgaaaa taaaacaatg ataacttcaa
    10081 attcaagtga ccctgtagtt ataaaaacta cagagccaaa gataaaggga gtgatagtgg
    10141 tagcaagtgg agcaagtgac ccaagcgtta aagagacact ttatagtgca gtacaaacat
    10201 cattacaagt agctggtcat caagtagaaa tatattctaa ataaatacat ataaccgggg
    10261 ggataaatga atgaagttta attataaggg aagaggattt gtaataataa ctttaactgc
    10321 aatgttagtg gtagtaggaa cagtcaatta tcaattaagt aagaaatctt tattagaaac
    10381 atcaaaagag tttaaggcat atgaagaagc gcagttacaa aaaaatactg atgatagtga
    10441 tagtagtaag acagaggatt ctaataatgt agataaacaa gatggtaagg aaagtgctga
    10501 tattgatata gttgatagta aaactagtaa agtaaaagaa aaggcaactg agacaagtaa
    10561 ggaaataaaa gctcaattat catcagagaa aaatatgaaa aaggcatctt atattttaga
    10621 tatgaaaatg aatagagaaa aacaaagaaa tgagttggtt caagatttaa atgaaatgat
    10681 aaataatcca tctacaacag aagaatctag aaaagaagct tctaatatga aattaaatat
    10741 agttaaaata caagaaaaag agcttcaaat agaaaatctt ttgagtacaa aaggatatga
    10801 agaagcatta gtttatataa gtgataacaa agttaatgta gttgtaaacg aagctaaatt
    10861 agaaaagaaa gatgcagcaa aaatatttga tttagttgca gaacaagcca atgtaaagta
    10921 tgaaaatatt aaacttacaa ataataataa taagtaaagt ataaacctca gaattaactg
    10981 aggttatttt cttgcaaagt agacttgtat ttggtattat tatacttata aaaatagttc
    11041 cttaaaatca ggaggtaagt tttaatatgg aagataataa atttggacaa gtaaaaatat
    11101 ctaatgatgt aatagctaca atagctggtt tagcagcatt agaagttgaa ggcatagaaa
    11161 ctacagcaac attaacagat aagttgttaa aaaataatgg agtaaaaata caaatcgaag
    11221 aagaggatgt taatctagat gtaatggtta cgataaagta tggaatgtca ataccagata
    11281 cagcttttaa agttcaagaa aatgtaaaaa atactgttga gacaatgaca ggactgaagg
    11341 tttctcaagt aaatatacac attcaaggaa tcagctttaa gaaggataaa gttgataaag
    11401 aagaagcaaa agcaactaag aaaaattaat attagccctc tgaaaagtca gagggttttt
    11461 tgctgataat tgattttata tggataatta aacttaaagg agaattttaa ttgatgaaaa
    11521 aagatagggc acaaaagagt acaacaagag aatatataat gaaacttata taccaaataa
    11581 atattaataa agaagatttt gaaactttag aagatagggt agataatttt ttaaaagata
    11641 attcagaaca tattataaat agatataagg agcttgcact tcagtattca aaaaatacaa
    11701 atttaaagtt agaagatact gaaattgaag atgttataga caaaaaatat ataaatacag
    11761 tatgcaaagc actaaaagaa aatcatgaca agatagatga gttaataaat aagcatgcta
    11821 aaaactggac agtagataga atgccaaaag tagatgtttc tatacttaga ttatctgtgt
    11881 gtgaaatact ttatttagac actcctaata aagtatcaat aaatgaagca gtagaacttg
    11941 caaaaatata ttgtgatgat aaatctccta aatttataaa tggtatattg ggaagtgttg
    12001 ttgatgaaat tgggaaataa tataataatt ggaattgata ctagctgcta tactacttct
    12061 atagcagcta tctctttaga taagaaagtt atattcaatg aaaaaataat gttagaagta
    12121 atggataatt caaaaggttt aaggcaaagt gaagctgtat tccaacatgt caataattta
    12181 gggattctta gtgataggat aaaatctttt aaagataggt ttcatgtaga aggggtttgc
    12241 tcatcaaaaa aacctagacc tgttgaaaat tcatatatgc ctgtattcaa tgtaggtcat
    12301 aattttggga gattattgtc tagtatatat ggttgtagat tttatgagac tactcatcaa
    12361 gagaatcaca ttgaagcaag tttattaaat agtaaattaa aaaataataa tagatttatt
    12421 tctgttcata tgtctggtgg tactacagag atacttttaa caagcaaaca agatagtcat
    12481 cacaatgtat gcgatattga tttaagtaaa tttgccaaaa caagtattaa aaaagatgat
    12541 aaaagtaagt tatacaataa ttttggatat aatatagata taattggagg aagtaaagat
    12601 attagctttg gtcaacttat agatagggta ggagttaagc ttggatataa atttccttca
    12661 ggaaagtatt tagatgaaaa tgctttaaat tgtaatctta aaatagaaag tggtctgaaa
    12721 acctctgtaa gagatggata tatgaattta tctgggttag aaaatcaggt aaataagatt
    12781 ataaaggata atggagataa tgctaatcaa aaagaatata tatctaaatt agtattagat
    12841 tcagtagtta gaaatatgtt taaatcttta gtatatttat gtgaaactta taatgtaagt
    12901 gaagtagtat ttgctggtgg agtttctgca agtaagtata tttttagaga attaaccatg
    12961 aaattaggaa aaaagcatat agaagcttat tttacagaac cacaatattc aactgataat
    13021 gctgttgggt gtgctataat aggattgaat aactttttag gagaaagagt atgaaactaa
    13081 gagctttaga tataagtgaa gcaaattcat atattaaaag aattttaata aatgacccaa
    13141 tactttctaa tcttaaagtt aaaggagaga tttctaattt taaggttcat agtagtggaa
    13201 atgtatattt atcacttaaa gatgaaacat caaagttaaa ctgtgtaatt tttaaaagta
    13261 attttaatcg taatctaaaa ctagataatg gtattaaagt tatagctaat ggatatatat
    13321 cagtttatga aagagatggt gcgtatcaat tatacattaa tgaaattgaa atagagggaa
    13381 tagggaattt acacatagaa tttaatagat taaaggaaaa acttaataaa gaaggattat
    13441 ttgaccctaa atacaagata cctataccta aaatgccaaa ctcaattggc gttataacat
    13501 ctccaacagg tgctgttata agagatataa taaatgtgat aagaagaaga tatccgaaag
    13561 ttaatataaa gctttatcca gtaacagttc aaggagataa atcagctgaa gaaatctgtg
    13621 aagcaattag atttttcaat catatgaaga atgttgatac acttatagtt ggtagaggtg
    13681 ggggttcaat agaagaactt tggtctttta atgatgaaat ggtagcaaga gaggttttta
    13741 attctcaaat tccgataata tcagcagttg ggcatgaaac tgattttact atttgtgatt
    13801 ttgtatctga tatgagagca ccaacaccgt cagcagctgc tgagattgct actccatcat
    13861 tggatgatat aaactataag cttggaaaca taaaaagtag gttgagtaag tcccttacaa
    13921 atcaaataga gctagaccaa tatagattag aagcagtatt taataagata aataactatt
    13981 tagattctta cacaataaaa gataaagtta tacaattgga caaaatatat gataaaataa
    14041 tttttggaat agaaaataat ttaagattag aagatgaaaa gttagtaaaa attggagcat
    14101 tacttcataa tttaagtcca ttagctacta tggatagagg ttatagtata gctcaaaaaa
    14161 atggaaaagt aataaatagt ataaaaggat taaaaataaa ggatagtata gatatagtat
    14221 taaaagatgg aaatttagaa tgtatgatag aaaaaattga aaataaagag gtatagtatg
    14281 aatttaacct acgaagaagc ttataaaaga ctagagagca ttttaaatga gttagaatct
    14341 aaaaatgcta gcttggatga atctttaagc ctatatgaag aaggtataag cctttataaa
    14401 cattgtaata agcttttaga tgatgctaaa ttgaaaataa gtaaatttaa tcaattagga
    14461 atagaagaag actttaaaat agaggaggaa taaaattgga atttaaacaa tgcctaaaag
    14521 aaaaagcaag ttttgtagaa aaagtactta aagaatatat gcctaaagaa gaagggtatc
    14581 aaaaaactgt tattgaagct atgaactata gtttaagtgc tggaggtaag agattaagac
    14641 caatacttac attagaggca tgtaaaatag ttggaggaaa tgaagatgaa gctattcctt
    14701 ttgctattgc aattgaaatg atacatacat actcactaat acatgatgat ttgccagctc
    14761 ttgacaatga tgatttaaga agaggaagac caacaaatca taaagtatat ggagaagcta
    14821 tggggatttt agcaggagat gccttgttaa actatgcttt tgaagtaatg cttgcaggct
    14881 caatcaataa agaaaatcca gaaaagtatc taaaagctat aaatgaaatt gccaaaggtg
    14941 ctggtatata tggaatgata ggtggtcaag tagtagatgt agaaagcgaa aacaaacaga
    15001 ttgaaaaaga aaaattagat tatatacata tgaataaaac tgctgcaatg atggtaggct
    15061 gtatgagagc aggagctact ataggtggag caaattctga acaaatggaa gaaataacta
    15121 aatatgcaaa aaatatcgga ttatcattcc agatagtaga tgatatacta gacatagtag
    15181 gagatgaatc taagttaggt aaaaaggttg gaagtgatat agaaaatcat aagtcaacat
    15241 acccatctct tttaggttta gataaatcta aagaaattgc acataatttg attgatgaag
    15301 caaagaaaag tatagaaaaa ttatctgatg atgtagattt tttaaatggg ttggctgaat
    15361 atataataga tagagaatac taaaatatac agctaaaatc gaggagggaa aaatggattt
    15421 tttttcggag atttttaaca atggggcttt gggaataagt ctgattgctt gtttcttagc
    15481 acaatttata aaaatattta ctggtaagga aaaaagaatt gagttatcaa gaatacttat
    15541 ttcaggaggc atgcctagtt cccatagctc ttttgttaca agtttagcta cagtggtagg
    15601 tattgaaaaa gggtttaatt ctactgattt tgctataatt accgtgcttg ccttaattat
    15661 aatgtatgat gcagcaggtg ttagacgggc tgttggtaaa caagctacta tattaaatca
    15721 aatggtggca gatatacagc atgggaagca tatagagcag aagaaattaa aagaattaat
    15781 aggacataca ccactagaag tttggtttgg agctttactt ggagtagtaa cagctttaat
    15841 attgatgtaa attgaaaatt tacagaataa aggtgaggat aatatgtata aatatttaga
    15901 taaagtaaat tctccaaagg atataaaaaa tatgagtata gaagaaatgg atttacttgc
    15961 aaaggatata agaaagttct tagtaaaatc tgtttcaaag acaggaggac acttagcttc
    16021 taatctagga gtggttgagt taacattagc acttcataaa gtatttgaca gccctaaaga
    16081 taagattgta tgggatgtag gacatcaatc ttatgttcat aaaatagtta ctggaagaaa
    16141 agattgtttt gtatctttaa gacagtttaa tggactaagt ggttttccaa aggagagtga
    16201 aagtcctcat gatatttttg acacagggca tagcagtaca tctatttcta tagctacagg
    16261 tattgcctgt gctagggata taaaaaaaga aaactatagt gttatatctg tgataggaga
    16321 tggttctata acagggggta tggcgcttga agctttaaat caattgggat atataaatac
    16381 caatatgata gtaatcctta atgataatga gatgtccata gataaaaatg ttggaggtat
    16441 gtctaaatat ctgtcaagta ttataaggaa ctcaacagtt gagaaaatga cagatgaagt
    16501 tgataaaatt ttaaatgtta cacaaacagg tgaaatttta tctaagactg cacatagatt
    16561 taaagataaa ctaatgtata gcttttctcc tcaggactgt tcattttttg attcattagg
    16621 tataagatat tatggaccta tagatggtca taatactaaa gacttaatag atatattgag
    16681 aaaagctaaa cacaaaaaag gacctgttct tttgcatgta attacgaaaa aaggaaaagg
    16741 gtacaggttt gcagaagaac aacctgataa atatcatgga gtatcaaagt ttgatataaa
    16801 gacaggtgtt acatctggga aagtcaagtc tatgtcaact agtgttggag aaaaacttgt
    16861 tgatatggct aataataatg aaaatatagt agcaataaca gctgcaatgc catctggtac
    16921 agggctaaac ctatttgaaa gtgcatatcc aaaaagatat tatgatgttg gtatagctga
    16981 acaacatgca acaggatttg cagcaggtct tgcaaaaaat ggtatgaaac cttattttgc
    17041 tgtgtactca tcatttttgc aaagggcata tgaccaagtt attcacgatg tatgcataac
    17101 aaaaaagcca gttacttttc ttatagatag agctggatta gttggaaatg atggagaaac
    17161 tcatcatggt atgtttgatt taagttactt aaattctatt ccaaatattg tagtaatggc
    17221 gccaaaagac acaagagagt tggaacttat gatggatttg tcattaaaat tagattgtcc
    17281 actagcaatt agatatccaa gaggaagtag ttattaccta gataagggag aatatggaga
    17341 gattgtattg ggtaagtatg aggtattaga taatgggcaa gatacagtta tactttgtat
    17401 tggaagtatg gtaaaacatg ccttagaggc taaagaaata ttatcaagag aaggaataaa
    17461 tccgacaata gttaatgcta gattcttaaa gccaattgat gaagatatgt taaaagtatt
    17521 attaaaaaat cataaaaatg tagttactat agaggataat attgtaactg gaggatttgg
    17581 aagtagaata aataagttta ttatagataa tgaatataat gtaaatatac ttaatatagc
    17641 aataccagaa gaatttgtaa aacatggcaa tgcagacgaa ttatatgatt ttgtgggatt
    17701 atcgccaaag agtattgctg ataaaataag gaaattattt attaagtaaa aatttaatgt
    17761 agatattgta aattaaaact tatataaaat ataaaattta tcaattagaa taaatatcaa
    17821 gtgtgttact tcaagctact ttagttatta ttaaagtagc ttttaacaga aaggtaattg
    17881 tatgaaaaaa agaatagatt tattgttagt agaacaaggg cactttgaaa gtagagaaag
    17941 agccaaaaaa gcaataatgg ctggattggt ttttgttgat aatcaaaggt gtgataaggc
    18001 tggtacagaa gtaaaagaag actgtaatat agaagtaaaa ggaaatccaa taccatatgt
    18061 tagtagaggc ggtttaaaac ttgaaaaagc aatgaaaaat tttgatttga ctattgatgg
    18121 gaaagtatgt atggatatag gtgcatccac aggtggcttt acagattgta tgcttaaaaa
    18181 tggagcaata aaagtatttt ctatagatgt tggttatggt caacttgcat ggaagttgag
    18241 acaagatgat agggttgtgt gtatggaaag aaccaatata agaaatgtga caatagaaga
    18301 tacaaagcag tttgcagatt ttgcatcaat tgatgtatct tttatatcgt taaagttagt
    18361 tcttccaaag gcaaaggaat tagtacgtca tgatggggaa attgtcgctt taattaaacc
    18421 tcaatttgaa gcaggaagag aaaaagtagg taaaaaagga gtagttagag agaaatctac
    18481 acatatagaa gttataaaaa tgatttctga tttttcagtc gaaaatggat ttgagatttt
    18541 agggttagat ttttctccta ttaaaggtcc tgaaggcaat atagaatatt taattcattt
    18601 gagaaatgga aatgatggat atgaatttga tggtgaaata tacaataaca aaatagtaga
    18661 agttgttgaa gcttctcata atttagaaaa ataggttaaa agggggctta gatttgatcc
    18721 tcgaattata tatgaaaaat tgcgccttag ttgaagaact aaggttgaat attgataaaa
    18781 acttaaatat acttacaggt gaaactggtt caggaaaatc tataataata gatgcacttg
    18841 gactttgttt aggtgacaaa tatgataggt cttttttaag aaaaggaaca gataagggac
    18901 ttgttgaggc tgtatttttt tcagacaata catatcttaa aaaaatatta gaagaaaatg
    18961 atataagtat agaagatgat aatttattgg taataaccag attgatatac tcagatggta
    19021 agagtactgc tagagtaaat ggaaggactg ttaaagtgtc tcttcttaaa gaaattgcat
    19081 ctacacttat agatatacat ggtcaacatc aaaatcaagc tttatttaat aaagatactc
    19141 acttaaaatt tctagacctt tttggagaaa atgaattaga agagtttaaa attgcttata
    19201 aaaatgtgta ccataagtat agtgaagtaa aaaaagcttt aaattgtttg acagaaaata
    19261 aagatgagat gcaaatccaa cgagaaatag atttattaag atttcaaata aatgaaattg
    19321 aagctgcaaa tctaaataag aatgaatatg aagatttatt aaaacaaaga gaagtttata
    19381 gaaatagtga aaagatatat aataatctaa attcgagtta tagcaagtta cataatggcg
    19441 aatataatgt tattgaccta ataggtcttg catctaaaga acttaatgac atatctaaat
    19501 atgacagtgt tttaagtgaa tatagtgata ctgtagagag aattatgtat gagttacaag
    19561 atatatctgg ggagataaga aattacaaag ataatataga ctttgaacct tatgagctag
    19621 agcagattga gcttagaatt gatgagatta ataatttaag aagaaaatat ggagatagta
    19681 tagacgatat atttgagtat tatagaaaaa ttaaagatag attagatgaa atattaaata
    19741 gagatgaaag agttgaacag ttaaaaagca aactgatgaa gatagaagaa gatttaaaaa
    19801 taaaagctag taaattgact aaagctagaa tagaagtagc aactacttta gaaaaaatac
    19861 ttcttgatga attaaaaagc ttaaatatga aaaatgtaat gttcaaggtt aattttgaaa
    19921 aaggtctatt tactttagat ggagtagatg atattgaatt tatgatatct tttaacttag
    19981 gagaagacat taatcctata tataaagttg catcaggtgg tgagatgtct agatttatgt
    20041 tagcatttaa aaccatattg gctgatatag atgatattga tacattggtg tttgatgaaa
    20101 tagatactgg gataagtggg atagcagcac agattgttgg tgagaaattg agtgatatag
    20161 caaagaaaaa acagataata tgtataactc atttacctca aattgctgca aatgcagaca
    20221 ctcattactg tatagagaaa gatacttcaa ataataggac gtttaccaat gttagtaagt
    20281 taaatgaatc tcaacgaaaa aatgaaattg ctagacttat agcaggtaac aatataacag
    20341 aaaaaactat tgaacatgca agtgaaatca ttgaattggc taaaaagtgt tagtgaaaaa
    20401 taagcatttt aataggtgta aagaattttt atagaaatgc tttacatcta ttttttatga
    20461 tgaaattatc ttaaaatatc tagttcctat actgaagaaa agtgagttta aaaatggaat
    20521 aaaatttgta taaatttgta actttgaaat ttctaaatgc ttaagtataa tattatttat
    20581 taaggtagta gtgaggggag gcataaaatg aataaaaaag atactttgca cttaattttt
    20641 ataatcgtaa tttttatttt attgtggtat gttgtggtaa cagtaagtga gattaataaa
    20701 aatattgaaa gttgtagtaa caagctagat tatttgtcac aagagattat gagcactaag
    20761 tcggatatta gtaatactat aaatgaagaa atgtcaaaaa gttatataac aaaaagtatt
    20821 gacctaaaag taaaaaaaat cgagaaaaaa gaatgtatta ttgatgtaga tgttcaatta
    20881 agcaaacttg gagaaaatgg gaaagtattt tttatgtaca aagaagagag taataaatgg
    20941 aatgaaactg agatgacaaa acatggagaa ttatcgtatg tatgtgaaat aaagataaat
    21001 acaggaagtg aatatgacta taaagtagtt acaagtggag ctatatctga aagttctgat
    21061 gtgcaaaaac tgactaaatc tgattatatg cctgaacaac ctatatttag ttctgggata
    21121 agagataata gagaatactt tattgaaatg gtagaaaata gtaatctttt taatcatgag
    21181 agtgaaaagt caaaaaataa ggcttataat aatattagat tagaaaaagt agatattatc
    21241 gtaaatgaag gaaaaaaaga tactgtatac aaagctaagt tagttgaaag cttagatgat
    21301 ggtaaaacta ataattccaa tagaaaccaa gtgaattatg aagcaagttt tcctaaaagg
    21361 gatattgatg acataattta tattaaagct aaacttacat acaataatgg agtagaatat
    21421 acaaaggata taactgaaga tataactatg ggattgcaag atttagaaaa ttaaatacat
    21481 atttaaataa atattcaagt ggatttgttc aataaaatag agtataaata aaactgtagt
    21541 agttttattt atactctatt aaaaaattat aattttaatt ccatatatct agcgccttca
    21601 attggattat aagtataagg ttctatatca taaaaaccaa actttttata taatccttgt
    21661 gcacttttca tgcttggaag agtatctaac ctcatgtgtg tatatccaat ttttttagct
    21721 tcttcaatga tttcttccag tagtattttt cctattttta atcctctaaa ttgatttctg
    21781 acatataatc tttttaattc acatatttta ccttcaagtt tttttaaagc aacacaacct
    21841 gctaaatttt catcaacaaa tgccaatatc aatgagcctg aaggtttttt atattttcct
    21901 ggaagtgttt ttaattcatt attaaagtct tgaaaacata agtctatatt tagagaattt
    21961 gaatattcag taaatagaac ctttacgttt tcaaggtttt ctaagtcttt ttcttcaaca
    22021 aattgtaaag ttatattttg agccatttta tccgccatta tataaacatg tttatataat
    22081 gacttcacct ccttgatata tgtatatttt tcttaatatc aattagattt taataccatt
    22141 actttttcac cgccatagtc aagctctcca ttaaactcaa atccaaaatc tttataaagc
    22201 ttaatagcca ttttattgtc ttcgaatata ctaagatata gttcatcaca gttatattcc
    22261 tttttaagat gatttacaag aaaatctagt gatgcttttc catatcctct accttgatat
    22321 tttgaatcaa tcataaatct atcaagccaa actctatcat cttctaaacg accatacata
    22381 gcaaatccta ttaaagaatt ttcatcatat attccaacag gtatccaagc tgttataaat
    22441 ttagattcag caatagaaag tgcattgctt tctatataat ccaattgact tttatctaca
    22501 gacaaattaa ctaaatcacg ccaattattt atgtctgcaa ttcttacatt taatttcaag
    22561 atattaccgc ccttcaaact ttttgttaca atataatact atcatattat gtattaaaaa
    22621 tcacttatta aggttttaag tgaacttttt gaatgaataa attctcagga aaaaggaatt
    22681 ataaatacat aataatacag cataggagta gatggatata tgaacaaaat aaataaaaat
    22741 ttcaaaaaaa tttggataat attaggagct gtatcgattt ttactatggt tataattttc
    22801 aataaaaatt gtaatgtaaa taaagagacc caaatagaag cttttacaat taagaatcaa
    22861 gataaaaaat ttgtatatcc tatgggaaat ataattggag taaaagcaaa tacagacggt
    22921 gtattggtct taggatatga ggaagaggat gtagactata ttggaggcat acaaattggt
    22981 gataatatag taaaaataga taataaaagg ataaaaaata gtcaagatgt atcagagatt
    23041 ttgaataaga ttaaaaaaag taaagttgaa gtgacttttg agagaaaaaa taggtataaa
    23101 acagaagtaa tagaaactaa aaaagaaaat ggcaagtata agcttggctt atgggtaaga
    23161 gataaaatat ctggaattgg aactatgact ttttatgacc ctagtatgga aaagttcaaa
    23221 gcaatcggtc atgctataaa agattcggat actaatgaac tattaaagat aaagcaagga
    23281 tatatatata agccagaaca attgaaaata gtaaaggcta gtaatgaaaa agtaggtaaa
    23341 ataaaaggag attttaatga cagcaattta atgggtaatt tctcaaataa ttcagagcta
    23401 ggtataagtg gtaatattac agaaaaccat aataaagaat ttaatgtagc gaataaagaa
    23461 aagcaattaa tagaagttgg aagaccacaa gatgtaaaaa taggagatgc agtaattctt
    23521 tttgaggata aaaacaaaaa cataacaagc tatgatataa aaatagaaag tatagtgtat
    23581 gataaaggaa attatagaga tatggtaata aaagtagtag atgacaagtt attggaatac
    23641 acaggaggta tcgtacaagg gatgagtgga gctccaataa tacaaaataa taaaattatt
    23701 ggtgcaataa ctcatgtttt tagagataat ccgaaaaaag gatatggtat ttttatagat
    23761 gaaatgataa aattgtaggt gaggcattaa aaaattttat tattttatca attatctagg
    23821 aggaatataa ttttggagtg tcgaatatgc tttagagtag ataattagga agcaattgtg
    23881 taaaaagttt agttttctgt aataagaaga tgttttttaa tggggggatt tttagtggaa
    23941 aaaatcaaaa tagttttagc agatgacaat aaggattttt gtcaggtatt aaaagagtat
    24001 ttgtctaatg aagatgatat cgatatatta ggcatagcta aggatggaat tgaagcatta
    24061 gacttagtaa aaaagacaca accggactta ttaatactag atgtaataat gccacatcta
    24121 gatggattag gtgtaattga aaaattgaat actatggata tacctaaaat gccaaaaata
    24181 atagtactat cagcagtggg tcaagataag ataactcaaa gcgcaataaa tctaggagca
    24241 gattactaca tagtaaagcc atttgatttt gttgtgttta taaacagaat tagagaacta
    24301 gtttctaata gagttacaca agttgagcca aaacctagac cagttcaaga gactcaaatg
    24361 actagaagtg attttgttaa gaatgtagga aatatagaga cagaaatcac aaatataata
    24421 catgaaatag gagtaccagc tcatataaaa ggctatttat atttaagaga agcaataaaa
    24481 atggttattg ataatgttga gcttttaggt gcagtaacga aagagttata tccaagtata
    24541 gctaaaaaat tcaatacaac accaagtaga gttgaaagag caataaggca tgcgatagaa
    24601 gttgcatgga gtagaggaaa agttgacaca ataaatcaac tatttggata tacggtacac
    24661 aatactaaag gaaaaccaac taactcagaa tttatagcaa tgattgctga taaattaaga
    24721 ctagagcata gtatggttaa ataaacagac ataaaaagta aggcttttta attaaagcat
    24781 tggctataaa tgcgcattac aagcagcgaa acggtataac cagtagggtt ataccgtttc
    24841 gctgttttaa taaatataaa aaatttcctt attatttgtt tactatatca atataataat
    24901 tttattatac tatggatata gtatgtgtct ttacaagttg tgaattgaca gtggtttatt
    24961 ttttaatata aatattgatt ttggtgcagg taaactttgt atttttaagc gtattatgga
    25021 atatgttaaa taaaaaaatg atgaaatata gtattgtaaa tgccaaagat gcaaaacaaa
    25081 cttaaaacat ttattttatt gttaagtaat gctataatat aatgtgattt taataatgat
    25141 agtggaggtt taaatatgag agtcgaggcc cctataaaag tagatcgaaa aaccaaaaaa
    25201 cttgctaaaa gagttgaaag tggggaaata gcagttataa atcatataga catagatgaa
    25261 gttgctgcaa actctttagt agaagctaaa ataaaacttg tcataaatgc ggctccttct
    25321 ataagtggga ggtatcccaa taaaggtcca ggaatattaa ctgaaaataa tatactaata
    25381 attgataatg ttggagaaga attatttgaa gaattaaaag aaggagaaac tatagaagtt
    25441 gtagatggaa agatatatag aaaaggaaaa tttttaggtg caggagaagt tttagacaag
    25501 tatgaggttt cataccaaat aaaggctgcc tatgagaatt tagctgtaga attggataga
    25561 tttatagata atactataga ttatgctaaa aaagaaaaag gatttatact tggagaagta
    25621 gaaattccaa aagtgaaaac taattatgct aataaacatg tattgatagt tgtaagaggt
    25681 caggactaca aagaagatct aagtactatg ctttcttata tagaagaggt aaagccagta
    25741 ttggttggtg ttgacggagg agcagacgct ttaattgagt ttggatatac tccagatgtg
    25801 attgtagggg atatggatag tgtaagtgat gaagctttaa aaaaggctag tgaaatagta
    25861 gtacatgctt atacagatgg aagagcacca ggtcttaaga gggttgagga attaggctta
    25921 gatgcagttg tatttcctgc gccaggaact agtgaagata tagctatgct tatcgcttat
    25981 gagtataaag ctgagttaat agtagcagtt ggtacacatt caaacatgat tgattttctt
    26041 gaaaaaggaa gaaaaggtat ggcaagtact tttttagtta gactaaaaat aggttcaaag
    26101 cttatagatg ctaaaggagt taatttgtta tatagaagta aattaaaaat aaagtacata
    26161 tgggcattaa tagcaacagc attatttcct gtgttggtag ttgcatcatt gtcaccagga
    26221 gttcaacagt ttatacaact aatgcaatta aagtttagag tattattaca gatgtaaatt
    26281 ttaggaggat aaatatgcat attaatatga aatattatat agtcactata ggggctatat
    26341 ttatagcttt gggtataggc atgttagtag gttttaattt aaataataat caacaattaa
    26401 gtgagcaaca agcaaatata ataaatgatt tggatgataa gtttaatatt ttaaaagaaa
    26461 aaaatgataa acttgacagt gacttagcca atgtaaatag agattatgaa gaggcagtta
    26521 attttataaa taaaaatgta gataagattt tagctggctc attgaatggt aaaagtatag
    26581 gaataatatc ggctaatgaa aatgatgatt atacaaaaaa tatagaagac ataataaata
    26641 aatctaatgg aagtattgca tttaatatag tgttaaaaga aaatataaca aatccagaaa
    26701 agttaaagga aatgtcaact aaactaggta cagatgtaaa aaatgcaaat gatgcagtta
    26761 attatataat cgacactctt aaaaaagaag atgcaagtga tattttaaca tatcttcaag
    26821 aactagatgt aataaagttt aactctcttg gaaatacata tctaaaatat gattctgttg
    26881 taatagctgg tggaaatgat gcaaaagaca gtacaaaaca gtttgaaaaa atagaaaaat
    26941 ttgtagtttc aaaacttaaa tcagaaaata aatatttagt agaagttcaa aatacaggag
    27001 ttaaaacttc ttatgtagaa ctatattcta aaaataaagt tgcaactata gacaatattg
    27061 atgaaggtat aggaagtata tctctagcta ttcttctaca acaaggtaat atagttggta
    27121 attttggtag attagatact gcaacttcat tgttgccatc tattaagtag aaataacttt
    27181 aaggagagaa aaaatggatt cttatataag tataataata ccagcttata atgaagaaag
    27241 tagaataaaa tatacattag aaagcatatt ggacattaat caaataaatg aaataatagt
    27301 tgtcgatgat ggttcgattg acaatactgc taaagctgta tctgaattag aaaatgaaaa
    27361 gattaaattt tttaagttag ataaaaatag aggtaaagga tatgctttaa attatggtat
    27421 caagttagca atgaaaaatg cagatgttat aggttttctt gatggggatt taggaagctc
    27481 tgctaaagaa gttgaaaaat taatagtacc tatattaaat ggtgaggcgg atgttacaat
    27541 agccaagttt cctcctgcaa aaagaaaagg aggtttggga tttgtaaaag gtttagctaa
    27601 aaattctgtg tttgagatga ctggcgttga gttagatgca actttatcag gtcaaagaat
    27661 atttaaaaga gaagttttag aaaagtttga tgaaatacct tttggatatg gagtagaagt
    27721 tggaatgacc atcgatatct taaagtatgg atttaaaatt aaagaagtat tagtaaatat
    27781 gacacataat gaaacaggaa gaaatttaaa aggttttatc catagaggga aacagtatta
    27841 tcatataaaa aaggttttag gacaaaaaaa gaaagaatgg aggtaatatc ttagtgaaag
    27901 attatatact ttataccatt ttattgttaa ctggattatt tggaacctat gctgtaattc
    27961 cactatttaa aaatttattg ataaatggaa atgtacttag accaaactac aaaaaagata
    28021 tgataccagt aagtatggga attgtatttt tacctatgat tgtaattaat ggaataatac
    28081 ttgctttctt tactacagaa tttaaggatt tagcgtatat atttatgttt atgtttggta
    28141 tgatatccat gttttttgca gggatattgg atgatgtcat tggaaataga gatgtaagtg
    28201 gtttaaaagg gcattttaaa agcttattta aaggaagtct tacaacagga ggttttaaag
    28261 ctttatttgg tggatttgta gggcttatag tttctgttgc tatatcaaaa gacataattg
    28321 atataatagt aaatacacta ataatagctt tatcaactaa tttaatgaat cttttggatt
    28381 taagaccagg gagagcaata aaagcatatt tattcataat ggtaattata tttttaacat
    28441 tgacaggatt tgttcaagtt cttccattac ttatagtacc aaatgtactt gcatacttta
    28501 actatgattt aaaagcgagg gctatgatgg gagatactgg ttcaaacgtt ctcggaatat
    28561 ctattggaat gctcatttct tttgggtatc catttaacat tagattagga tggttaatat
    28621 ttgtagttat tatgcatata ttcactgaga aatactcgtt aactaagata atagaaaaaa
    28681 acaaactatt aaattttata gataaattgg gaaggtagta ttatgataag caaaagagtg
    28741 ggtattgttg aatcaatagt aagtcaaact gaaactctag atgatataag agtaaatata
    28801 aatggagaaa tacaaagggc atataattat ccaaacatat ctggaactat aaatatagga
    28861 gatgaagtcg ttttaaatac aacagcagta gaactgagct taggtacagg tggataccat
    28921 tttgtaataa ctaatttaaa taatatagaa tctactttaa ctgaaggcgg tcatataatg
    28981 aaacttagat atacacctct tcaaataaaa gtagattctg ttgaggaaca agaaagtatt
    29041 tatcatgata aatttgcgaa ttttaaaggg ttagaaggtc tttctgttgt agtagggact
    29101 cttcatagta tgttaactcc atttgtagct tcatttaaaa gaaataatcc aaataaaaaa
    29161 ttagtatata taatgactga tggagcatct cttccaattt atttaagtaa aaatgtggat
    29221 actttaaaag aaaaaaagct aatagatagt acaataacta taggaaatgc gtttggtgga
    29281 gattatgaat gtataaatat atatactgca ctaattacag caaaagaaat actaaaagca
    29341 gatgtagtat ttgtaagtat gggacctgga attgctggga caggaacaaa atatggattt
    29401 acagggattg aacaaggctc tattcttgat gctgtaaaaa aacttgaagg aagagcaatt
    29461 gcaattccaa ggattagttt tgctgataaa cgagaaagac atcaaggtat ttcacatcat
    29521 agtatgaccg tatttaaaga aattgtaaat gtaaatgtag acataccaat aactatatat
    29581 gatgatgaaa aattgaactt tataaaagag caaatcaatt taaatggttt aaacaaaaag
    29641 cataatataa tttatataga taataataaa acgaaagagg atttagacta ttttaatcta
    29701 aaagtaaaga gtatgggaag aaattatgaa caagatgagg catttttcaa agctgcaagc
    29761 acagcagcat attacttaat ggaggtttaa gatggtatta gaagaaaaaa ctattagtag
    29821 tgatagggtt tatacaggta aagtaattac tttaaaggtt gatactgttg aaattccagg
    29881 gcaaggatat caaaaaaggg agttagtaga ggttggtgga gcagtaggaa tagttgcaat
    29941 tacagatgat aataaagttg tactagttaa gcaatttaga aaacctatag aaaagccaat
    30001 ctttgaaatt ccagctggta aactagaaaa aaatgaaagt ccaaaagaat gtgctgaaag
    30061 agaattaaaa gaagaaactg ggtatagtgc aaaaaatgtt aagttaatac ataagttttt
    30121 cacttcagca ggtttttcta atgagataat gtttgtatat ttagcaacag gtcttactcc
    30181 aggagagaat aatttagatg cagatgagtt tttagatgta catgaaattg agcttgaaga
    30241 agcatataat atggtactaa aaaatgatgt tgaagatgca aaaacttcta ttggattatt
    30301 attagtaaaa gatatgttta aaaattaata tttataaaat gaataaccct ttgtcctaaa
    30361 gcatattatt ttataaagga caagggggaa ttaaattgag aagaacatat agaaaaaatg
    30421 attttagaga attaaataga caaataatta ttataggatt gttgtttatg atgtctattg
    30481 ttgttgggtc ttacataaat aaaatattgc caagttctag taacaatata ttaaacaata
    30541 taaatcctgc tgtagagtat tataatttaa atataagcat aaaagatgca gtgatacaaa
    30601 atttaaaatc agatgcaatc tttatgggct caatagctct attaagtctg tttgtagtaa
    30661 caattccagc agtgttggta gcttttgtat taaaagggat gtcaattggt tatacaataa
    30721 atagttgtat attggcatta aaatttaaaa gtataaaaat gattttaata atattattta
    30781 aaaatttgat tattattcca tgtgcaatca tattaacatt aattagctta agttatttta
    30841 aagaaatggt ttatgaattt aaaaagaaaa atagaaaaaa tatgcaattt ttaattaaga
    30901 ggtatatact aaatattata attataatag cactatcatt ggggttgcaa ttaatattaa
    30961 atactgtaag tattggtatt attaagttcc tagctaaata aaggagttta taatggatat
    31021 tatagaggga tatatagatt acataaaaga taaaaaaaaa ttatcagaga atacagtggc
    31081 atcatacttt atggatataa aaaaatatat ggaatatata aatcaaaaaa gcattaaact
    31141 aatagatata gtagaaaatg atattataag ttacttaata aagttggaaa aagataatgt
    31201 atcaatagct acaatagcga ggatgatatc ctctataaaa tcttttcatg attatttatt
    31261 tttaaatcat atatgtacaa ataatcctgc aaaggatata aaaaaaccta aaataaaaaa
    31321 agaaaatata aatatactta cagaagaaga aattgaaaga ctattaaatt ttccaaagtt
    31381 aacaacacct aaattgatta gggacaaggc tatttttgaa gtattatatg gtactggtat
    31441 aaaagtatct gaattagtag agatgaatat agaagatatt gacctagaca ttgattatat
    31501 atattgtaat tcatgttgta aaagtcaaag agtgatacca ctttgtgata ttacaaaact
    31561 ttatttagaa aagtatctaa aagaagcaag acctaaaatg gctgtagaag gtgaaaaatc
    31621 attattcgta agttcgttag gtcaaaggtt tacacgacaa ggtctttgga aagtcataaa
    31681 aaaatattct aatctagcca atatcgataa aaatataaat cctacaatgc ttagacattc
    31741 atttgcaatt catctgttaa atgaaggtgc taacattgct gttgtaagta aaattttagg
    31801 aaatgttaat ttatctagtt tacaagtata tttaaatcat atagataaaa acgtgagaag
    31861 agaaataaag gaaaaacatc ctagaaatga tgttgatata gaattacaaa aagcagaggc
    31921 taaatagact atatagcaaa ttttataatt tagaaggagc atatttgtat gagcagagta
    31981 atttggattg taattgatag tgttgggata ggagcattgc ctgatgctga aaattttgga
    32041 gatagtaagg atgtaagtac tcttggaaat atatttagag aatacccaga tataaatatt
    32101 cctaatatga gaaaattggg tataggaaat atagatggtg tagatttttt tgaaagtata
    32161 aaaaccccaa taggttgttt tggaaagtgt aaagaaatgt ctcagggaaa agatactact
    32221 acaggtcatt gggaaatgac tggtataata gttgacaaac catttaagac atttgaacat
    32281 ggattttcca aggagataat agacgagttt gagaaaaaaa ctggaagaaa agtagtggga
    32341 aataaaccag cttcaggaac tgtaataata gatgagtatg gagagcatca aataaaaact
    32401 ggtgatgtaa tagtatatac atcagctgat agtgtatttc agatagctgc taatgaagaa
    32461 gtaattcctc tagaagaact ctataatatg tgtaaaatcg ctagggaaat aatgatgggg
    32521 gacaatgcag tagctagagt aattgctaga ccattcatag gtaagaaaaa aggtgagttt
    32581 gtaagaactt caaatagaag agattattca ttagacccat ttgaaccaac agttcttgac
    32641 aatataaaag aatcaggtct tgacgtttta gcagttggaa aaatagaaga tatttttaat
    32701 ggaaaaggaa ttacagatgc tatccacact aaaagtaata tggatggagt agatgaaact
    32761 ttaaattata tgaaacaaga taataaaggt ctgatatatt caaatcttgt tgattttgat
    32821 tctaaatatg gtcatagaag agacccagaa ggatataaga aagctcttga agagtttgat
    32881 agtagacttc ctgaaataat ggctaatatg agagaagatg atattttaat aatcaatgca
    32941 gaccatggaa atgacccaac atataaaggt acagaccata caagagaata tataccagtt
    33001 atgatttatg gcaataagat taaaaaaggt tttaatttag gagtaaaaga tacttttgct
    33061 gatattggag caactgttgc agatatacta aatgtaaagt tgcctaaaca tgggtcaagc
    33121 tttaaaaaag atttatttta aattagaaaa taacaaaaac ttagtttaat aggatggaga
    33181 gattggaatg tttgaaaaga tagcacaaag tagtaaattt ataaatgcta aaattaatat
    33241 aaaacctaaa attggtttaa tattaggttc tggactaggc gatttagcaa atgatataga
    33301 agactctgtc acaattaaat atagtgaaat tccaaacttc cctatatcaa cagtagcagg
    33361 acatgctgga caacttgtca ttggaaaact tgaaggaaaa gaagttattg ctatgcaagg
    33421 tagatttcat tattatgaag gatattctca aaaagaagct acttttccag taagggttat
    33481 gaaagaatta ggagttgagg ttcttatagt aaccaacgct gctggaggtg taaataaaga
    33541 atttaaagca ggagatttga tgcttataag agaccatata aactttagtg gaagtaatcc
    33601 attagtagga aaaaatgatg acagacttgg tgatagattt ccagatatgt cggatgcata
    33661 ttcttctaga tatgtagatg tagttaaaaa ctgtgctaaa gaatgtaata tagatgtcaa
    33721 agaaggcgtt tatatgtttt ttagtggtcc aaactatgag acaccagcag aagtgagaat
    33781 ggcacaaatt ttaggtgctg atgctgtagg tatgtctact gttccagaag tcatagtagc
    33841 ttcacactct aatataggag ttattggtat ctcctgtata acaaatatgg ctgctggcat
    33901 cttaaatcag tcactaagtc atgaggaagt aatagaaact actcaaaaag ttaaatcaga
    33961 atttatgaat ttagttaaaa caacagttaa aaatttataa gttgaagatt attataaatt
    34021 ttttgagcaa atttataata aaatagttaa tgtttaattt aaaaggatta ataaagagct
    34081 gtcttgatat agaaagttat ttctaataag ggacagtttt tttataatac tacaacattt
    34141 gaaagtgttt taaagtttaa tatttattta aattattata ggttagaatg gagatttcaa
    34201 ttatgagaat gtatgatatt ataagaaaaa agagagataa cctagagctt agtaaaaaag
    34261 agataaacta ctttatagaa aattattcaa agggagatat acctgactat caagcttctg
    34321 cactattaat gtctatttat ttgaataaga tgaataaaca ggaaactgta catcttacag
    34381 aagcaatgat gaactctgga gacatgataa acttatctga gatagatgga ataaaagtag
    34441 ataagcatag tacaggtggt gttggagata agactactat agctcttata cctttggttg
    34501 cttcatgtgg agcaccagtt gcaaagatgt caggtagagg tcttggtcat actggtggta
    34561 cgattgataa attggagtct ataccaggtt tctcgacaga aatggagata agtaaattta
    34621 ttaattctgt aaataagtct aaaatagcgg tttgtggtca aagtgcaaag gtagcaattg
    34681 cagataagaa aatatatgct cttagagatg ttacagcaac tgttgataac atatcattga
    34741 tagcatcaag tgtaatgtct aaaaaattag cttcaggagc tgatgcaatt gtgttagatg
    34801 taaaaactgg tgatggagca tttatgaaga cgttagaaga gtcttttgat ttagcaaagt
    34861 ctatggttga tataggcact ggtatgaata gagatacaat agggattgta acagatatgg
    34921 atgaaccttt aggttttgca gtaggaaact ctttggaagt tatagaagca attgagactt
    34981 taaaaggaaa tggtcctaaa gaccttgttg agctatgtga agtactagga gcatatatgc
    35041 tggttttatc aaaggtagca tatgattttg atgatggtgt tgaaaagata agagaatcga
    35101 taaaatctgg tgacgccata cataaactca aagagtttat agagaaccaa ggtggtaata
    35161 aagatgtagt agatgattat tctttattca aaaaatcaaa gtataaatat ccagttaaat
    35221 caactaaatc aggttatata aataaaatta aagctgaaga tgttggtgta tcagctatga
    35281 ttcttggggc aggtagagaa actaaagatg atgttttaga tttatcagtg gggataattt
    35341 tagaaaagaa agtaggagat tatataaatg aaggtgaagt tttagcgtac atgtattata
    35401 atgatgaaca aaaactttca ttggcaaagg acagatttat tgattcctat tctattgtag
    35461 attcgaaggt agaaaaaaat aaactaatat acggtattgt aactaaagaa gggattaaaa
    35521 agttttagaa aattttagaa aagtgattat aaaaggccta acatgtcaaa aataatgtta
    35581 ggttttttat tttttgataa gttgtaaatt ataccaaaaa tatatatttt aaaacatttt
    35641 ttacaatata aataagttta ttctacaaga tgattgaaaa ttaaagtatc tagctttata
    35701 atagaaaatg gataaatata cataaggagt agattatatt atgaacttta aagaaaatag
    35761 attgaaaata gcagcattaa taattgttat tttgattatc ttagcaggta tatttgtgtc
    35821 tatgcaaata ggtccttata ataaaaataa caaaaaagat gtaattattg acattccaaa
    35881 tggagcatct attggaaaaa tatctgatat attatatgaa aataaattaa taaaaaatga
    35941 actattattt aaacttttgg taaaggttag caataaagct ccatctataa aatcaggaac
    36001 atacttactt aatcaatcgt actcaaataa tgatataata agtcttttag tttcaggtaa
    36061 aatatatcag gatggtataa aagtgactat tccagagggt gctacatcta aagaaattat
    36121 agcaatgtta gtaagtaaaa atttaggaga taaagctact tttgaaaatt taataaaaaa
    36181 acctcaagaa ttttatgata aatttccata cttaaaggaa gatggaataa cttctttaga
    36241 agggttcctg tatccagaaa cttattattt taattcaaag aaacaatcag aagaagatat
    36301 tttaagcgaa atgttaaagg tatttgacag taaatacacg gacaagttta aaaagaaaca
    36361 aaaaaaatta aatatgactc ttcaagaagt aatggaaatg gcatcaataa ttgaaaaaga
    36421 agctgttctt gacaaagata gaccaataat agcaagtgtg ttttataata gacttaaggt
    36481 aggtatgcct cttcaatcag atgcaacaat acaatatata tttgaagaga gaaagaaaat
    36541 tgtaacgtat gatgatttaa aaattgattc accatataat agttataaaa ataagggatt
    36601 acctcctaca ccaatatcaa atcccggtat aaaatctatt gaagccgcgt tatatccaga
    36661 taaaacagac tatttatatt ttgtagctaa gattgatggt ggaaataatt atagtacaaa
    36721 ctatcaagac catttaaaat atgttaaaga atataaagaa gcaagggata aacaatcaaa
    36781 agatacaaaa gcaacaaata aagaaaatac aaaaaaataa accatgatta taaaaagcct
    36841 aacagggtaa gaataatgtt gggctttttt attgaaaatt gttattctta gatttataat
    36901 aaagaaagtg taaatatata caacaatatg aatttaaaaa ataataaatt aatataaaac
    36961 ttgaacattt attattttag ggagtgtttt tatgagtaat atagttaatg atttggtcga
    37021 agattatata agagtgacat taaaagaaaa agaaggattt ttaaaagatt tagaaattta
    37081 tgcagaggaa aatagtgttc ctataataca taaagaagtt tcagatttat taaaagtctt
    37141 attaaagatt caaaaaccaa agagagtttt agaagtagga tgtgcaattg gttattcttc
    37201 tatttttttt gcaactatta taggaaaaga tgcagacata ataactgttg agagaaatga
    37261 aaaaatgata gaaaaagcaa aagaaaacat aaaattagct ggatttgaaa ataacataac
    37321 tatactagaa ggagatgcag aagaaaaact tagtcaagtc caaggtgaat ttgaccttat
    37381 atttatagat gcagccaaag gtcaatataa gctatttttt gatttagtta tagataaatt
    37441 aaaagatgga ggacttttag tatctgataa tattttatat aagggtatgg ttgctcatga
    37501 tgattttgtt gtaagaagaa aaaagactat agttaaaaga atgagaaatt atttagatta
    37561 tatatgtaat tgtgattatt taagcacatc attgatacca ataggtgatg gtgtagcact
    37621 aagttataaa gaaagtaaaa gaggtgatgt agatggaatt aaataaagta gaacttttgg
    37681 ctccagcagg tgatttggag agattgaaaa tagctataac atatggagca gatgctgttt
    37741 atataggtgg agaaattttt ggaatgaggt ctgcagcgaa gaattttagt aaagaagata
    37801 tggcagaagg agtagctttt gcacatgaaa gaggaaagaa agtatttgta acagtaaata
    37861 taatacctca taatgaagat tttctacaat tagaagacta tttgttggaa ttagaagaga
    37921 taggaataga tgcagttata atagctgacc caggagtact tagtgttatt aaaaaagtaa
    37981 ttcctaatat ggaaatacat ttaagtacac aagcaaatac gaccaattat ctaagtgcga
    38041 acttctggta cgagcatgga ataaaaaggg ttgtagtggc aagagaatta tcttttgatg
    38101 aaatatctga gataagagca aaaacacctt tagacatgga tatagaagcg tttatgcatg
    38161 gtgctatgtg tatttcttat tctggtagat gcttaataag caactatatg actggaagag
    38221 atgcaaacaa aggttcttgc gctcaatctt gtagatggca ataccactta gttgaagaaa
    38281 aaagacctgg tgagtatttc ccaatatatg aagatgaaag aggtacattc ttctttaact
    38341 caaaagattt atgtatgata gagtatatac cagagttaat caaatctggt ataacaagtt
    38401 taaaaataga aggtagaatg aagactgcat actatgtagc tactgttgta agagcataca
    38461 gaatggcaat agatgaattt tacaaagacc cagaaaactg gaagttcaat ccaatgtgga
    38521 tggaagaact aaaaaaaggt agtcatagac attttacatc aggtttttac ttgaataaac
    38581 caacaacaga agaccaaaat tatcaatcag catcatatgt tagaaactat gattttatag
    38641 ggatagttag agaaacagaa gatgaagatg gtcttattgt tgttgagcaa agaaataaaa
    38701 tgtgtgttgg tgatgaaata gaggtcatgg gaccatataa agaaactatg tttactaaaa
    38761 ttgaagcaat gtacaatgaa gaaggagaag ctatagaatc ggctcctcat cctagacaaa
    38821 tagtgaagtt aaaactatca gtaaaagttg gtaaagatta tatgcttaga aaagttatag
    38881 aagaaaaggt tgaagaataa taaaaaattg ataaaaatag tattagcccc ttagaaattg
    38941 tcaataatga aattatctaa ggggtgattt catgtcaaaa aagaagactc catttttgaa
    39001 aaaagtggga aagagaagct ggtgtgtatt tactataatt ttaataattt atagtgcttt
    39061 aatttatagg ctagttgata tacaagtatt aaaaggtgat aaatacaaac aaagtgttga
    39121 atcacaaagt gttgagaaag tcgagctaaa cagtggaaga ggaataatat atgatagaaa
    39181 caacaagaag cttacagata caagtaagta tcaggtatta gttgttgaaa aagaaaaatt
    39241 aaataataac tataaaattt tggagcttat taagaaagct actaaaatga atgatttaga
    39301 tatatataaa gctgtacaag agcaattgac acgccctata atacagattc aggctaaaaa
    39361 tatcgataaa aatatgaaaa aagaacttga gaaaaatgga ataatgatag aagaaaaaac
    39421 tatgagatat tcaaaagatg gtttattatc acacacaata ggatatataa aagaagatga
    39481 taaatcaggt cagtcaggaa tcgaaaaaag tatggacagt gtacttagaa attcaaatga
    39541 aaagtatata agtgctttta aagctggaga tgcaggaaat gaaaaatctc taaacatact
    39601 aaagggaagt gtaaaaacta ttgataataa agataaagat agacatctaa aaactactat
    39661 tgattataat attcaaagga aattagaaca aatattaaat aaagaagaaa atcctacagc
    39721 agcaataatc tcggaggtat ctacaggtga aattcttgca atgtgttcta gacctaattt
    39781 tgaccaaaat gatatatcaa aaagtttaaa aggaaaaaat ggtgaatttg aaaatagagt
    39841 tataaaggcg acatatccac cagggtctgt atttaagatg gtagtcttat tttctgcact
    39901 tgaaaatggt gttatagatg aaaactatac gtacaactgt acaggcaaga ctaaagttgg
    39961 gaatactaat gaaatactac gatgtaataa aagagatggt catggtttcc aaaatttaag
    40021 acaagctttt tctaattcat gtaatcctgc atttttagat atagctatga agcttggaaa
    40081 agaaaagata cttaaatctg ctgaaaagtt gcatttattt gaaaaggttg atattggtct
    40141 tgatgaagaa aaaattagag aagctccaaa aaacatatca ataagaaatt tagctatagg
    40201 tcaagaaaat atagaattta caccacttca aataaatcaa atgactcaaa taatggcgaa
    40261 caatggaaca ttcaaaccat tatacttata taagagcctt gtggataatg atatgaatac
    40321 aataaaaact tataaatcct caaaaaagga agaacttatt tctccatatg tatgtacaca
    40381 agttaaagaa tatatgaaat ctgtgtctag gactggtaca gctaaggacc taaaagatat
    40441 tgagggtgga tgtggggtta aaactggtac agctcaaagt agtttgaata aaaaagcaat
    40501 agaccatgga tggataactg gattttatcc tgaagaaaga cctaagtatg taataactgt
    40561 attagtagaa ggaactcaaa aaggaaataa atctgcaaca cctatattta aggaaatatg
    40621 tgaaagtata caataaaatt atatactata aaatttaagg atatatcgta atcttgattt
    40681 tagatagaaa gttttgtcta gtgatgtacg atatatcctt taaaaatgta gtattaactt
    40741 tcttgaacaa gctctttttc tagtttttta agagcttttt tctcgattct agatacatat
    40801 gacctcgata tatcgagttt ttgtgcaatt tctctttgtg tcttatagcc ataaggagtt
    40861 aacccatatc ttaactggac aatttctctt tctctaggag taagaatttt gtttagttgt
    40921 tcgtaaagct ttccaacttg aacctttagc tcaacttcat caagaacata gttagcttct
    40981 gtgccaagta tatctaaaag acttatttca ttacacacta ctctttatat gttattggta
    41041 ttactagtct tcatgtaatt tcaaatgaac cattaattca aaagaatcca atttttgttc
    41101 tttagactta taataaactg ctttatcaat tacagatttt aggagtttat tttttccaag
    41161 ggaatctgaa tcatggtaaa gtgataacac agttttaata tcttctatta ttttagcatt
    41221 gtctttttta acagtactca atctattttt tactgtctta attgaatctt taatttcttc
    41281 agttcttgaa cttatattgt tggacctttc aataaatgta tcttcatcat atattccacg
    41341 ttctaataaa tcatataact tatttttttg cttactcaat tcttttaatt cagtttctaa
    41401 accctttaag actcgctttt gaaattctat attactgtct ttattatttt tatctaagtc
    41461 tatgtcagat gtttttaatt gatatttttt tacagtgtct tccaaagatt ttaaaatagc
    41521 agcttcaata aattcaaatc gagaactttt attgcaacca ggatggtaac aaattatata
    41581 gttgtggtct gcatatggtc tatatactaa tggcctacca caatttttac aaatcactat
    41641 tcctgcaagt ggatttttta tttgattacc atagctgaca tgaccatttt ttttgagtat
    41701 attttgagcc tttttccatg ttatttcact tattaaaggt tcatgctttc cttttgcttc
    41761 aatccattca tctttaggtc ttaatttaac tgtttttatt ttatttggat ttttagattt
    41821 tttatagtcc tttttttgcc actgaatgta gccacagtag actttatttt ttattatatt
    41881 tgtaattgca gaattgtacc aattagcacc tgtagcagtt ttaatgccta ggttatttag
    41941 gtattttgat attttactac aacccatatc ttcattgata tataagtcaa agatagtcct
    42001 aactatatca gcatctttat ttggtacaag tattctttct tttctaccag ttgttacagc
    42061 atcatatcca aatggagcag aagttcctat gaaattccct tcttcaactg attttattct
    42121 acctctttgc atccttcttg atataagttt tagttctttt cttgccataa atgcttcaaa
    42181 ttctgaatac tcttcatcaa attcatctgt taggtcgtat gtttttctag gtgtgatgat
    42241 tttggtctta ctttctttaa atgtttctag tatgatacct tggtctttca tgtctccacg
    42301 accaagtctg tctaagtcca ttactaagac tgcgtcgtat ttattttctt cgacttcttt
    42361 tagaagttca agcattttgg gtctatgtat tatactttca ccagaaacta attcttcttt
    42421 tatctcaatt acatctaagc tttgttcttt tgctagtttt agtagggttg atttatgcct
    42481 acttaaagtt tcaaattcgc cttgtttttc tgcttcttca tcagcacggg attttctcaa
    42541 gtatatggca acactcatat aagtaatcac actccttagg tactattata tattatatta
    42601 aggatataat gggataattt atgctaatta aaacttgata taattgtaaa aatagtatga
    42661 aaatttagca tgaatcgaca gcattcaatg agaaaatata gtataatgca attgagaata
    42721 atttttaggg ggtaattata tgtgtaattt taaaaaaata ctaggcttgt ttatgataat
    42781 tatgttatca gtttctatgg tagcatgttc tagtggggga gattcaaaag atgaaagcaa
    42841 aggtaaggac aagcaattta ttgaggattt aggaaaaggc ttaaaaaaaa gatgggattt
    42901 ggcatctaaa gaagaagctg gaacactaaa cttagagcag aatgaagctt atgaaaaatt
    42961 tgtagaagta gaaatggatg ctgtatcaaa atataaagat gctgagtttg atagcccaga
    43021 acttggcaag ttggcaaaag attatataaa agctcttgaa gattcaaagg aagctataaa
    43081 atattattca aacgaccaat taaaattttc agaactttgg gaaaagcctt ataatgagag
    43141 aagcacgata ttgttgactt tagttgataa gtttggtttg aaagtagatg aaaaagagtt
    43201 taaagtatta aaagacaatg cacaaatcgt aaatgaagaa aatgatttaa aagaaaaagt
    43261 taatgctatg gcaaaaggta taaaatttga aaaagtaaaa gatgaatatg attggaagac
    43321 ttatcaagct actgtagaaa atacaagtga tttagatctt caagattttt acttagatat
    43381 aaatctaata gacaaagatg gtgtaataat cgagacacaa acatcaacat cagtaaatgg
    43441 aacttggaag aaaggtcaaa aagttagact tgagtttagt acagataagg attttgaaaa
    43501 aatagagtgg acacctcatt attctgcaaa taattatagt ataactgaat agataatttg
    43561 tatttaaaaa tatttagaag gggaagatat tatgaaaatt aaaaaattat taacaatagg
    43621 gttatcttta tctatgttta ttgctagttg ccatatatct gcaaatgctc ttgataaaat
    43681 tgaatcaatt aaaggtgcag ataaatacga aactactggt ataattgcag ataaacaaaa
    43741 ctatactaca gctatattaa ttaatgcaga tagtacaatg gctgatggat taagtgcaag
    43801 tggacttgca ggagctacaa acgctccaat tcttttgact aagaaaaata acataccaaa
    43861 tgctacactt aaacgattag aaaaggcaaa aaaagtatat ataattggag gagaaaactc
    43921 tattgataaa tatactgaaa ctgttctaaa aggtaaagga atagagatta aaagacttca
    43981 aggtagtgat agaattaaga caagctataa tgttgcaaaa gaaataaatt caattaacaa
    44041 agtaaataaa gtgatattga ctaatgcttt taaaggagag cctgatgcaa tgagtgctgc
    44101 acctgtagca gttagagaga aagcagctat agtattaact gatggaaaaa gtgttccatt
    44161 taatacaact ggtgtagaaa gttatgtaat aggtggtact tcatcaatga atgacaaact
    44221 agttaatgat actaattcaa ctagattagg tggcacagat agatatgata ctaacaaaaa
    44281 gataataaat aaattttatg gtggagtaaa agaattttat atagcaagtg gtactgattt
    44341 agtgtatgct cttgttggtt ctactgttgc taaaaataat gctattgtgt tagttaataa
    44401 tgatagtaat aaaagtgtat taaaaagcac aactaaatta actgctatag gaaatttgag
    44461 tgatagtata ttacaacagt gtttaaatgt aacaaaaaat ataggagatt ctaatactgg
    44521 aagacaatat acagtagaag atgctgctaa tgcagtaaaa aaactgctag gtgtgaagaa
    44581 attttattat aatgaaaatt atccagaaga tgaagatgta atattcttac tagatgagaa
    44641 ttttgaattt tcaggaaaac aattctatgc atttggttat gttacagaaa attctgaagg
    44701 ggatgttaga tactgtgtag agaaaaatga tatgagcaaa gtttatacat ataatgttag
    44761 tggagttatg caagtatgta acccagatga ttataaaaag aaggaaatga tatcagaaga
    44821 aaaagcaaaa caattggcat tagaagagtg tgccagaaaa cataaagttg gtgttgattt
    44881 attaaaagtt aatattgctt atattgatga ttttgatgat ataaaagtat atgctgtaag
    44941 aatagattca aaaccacatc caaatcaaac ctatggatgg tattttatag atgtttatag
    45001 tggatatgct tataaggatg tttggaataa catttaaata gtgtttttaa ttatataatt
    45061 taccaatata tgttataata attttagcaa gaagatgtaa tctacaatct atagagtgga
    45121 gttcatacaa acaaaggatt atcctcccca ttttaagaag ggaggtgatt atgtatggat
    45181 aattttttac ttagtatatt agccagtatt ctggctagct atatagttta cttaataagt
    45241 aagttattta gaaaacgtaa aaaaccactc aaagctggca ctaagagtgg ttgggaactt
    45301 gattttaaaa taaagttcca taaattcaaa taacatcgtt tatgatgaac tccactctac
    45361 tgctaaatag attgtagttc ttcttgcttt tattatacca caaattggtg cagatattca
    45421 aaaataatat atttataata taataaaatt atagaagttt tgcagtgagc gaaatttgtg
    45481 ataaaatatg gcttaacaat tggaatataa tgcattgaag atgtgtgata agtattatca
    45541 attgcactac tcatggttca ctgcaaattt aagagagttg tatagatgta agtattggaa
    45601 atactcaatt tgttttgggg ttttatatta actaagtggt atgtaaagct caaaattaaa
    45661 tagttggcta tggttaaggg attgccgttt tatattaact aagtggtatg taaagataat
    45721 agcagatatg atgtttaata acggaagtat aaggttttat attaactaag tggtatgtaa
    45781 agctgaatga acctaaggta gttgaacaga ttgaaaagac gttttatatt aactaagtgg
    45841 tatgtaaagt atgtcaggac ttcttaaacc atattcagca tacactcgtt ttatattaac
    45901 taagtggtat gtaaagaaat ttaatattgc tggaaaagga gaaatggata ttggttttat
    45961 attaactaag tggtatgtaa agaatgctga acttaaagta atgatgctat tttgggacag
    46021 ttttatatta attaagtggt atgtaaagaa atttgcaagg ctaaattgcc ccttaattaa
    46081 tggtggtttt atattaacta agtggtatgt aaagagtttt tctatatatt cagatatttc
    46141 acttttatct tgttttatat taactaagtg gtatgtaaag gaaatatgta tagaagcatt
    46201 gaaacaagat aaatattgtt ttatattaac taagtggtat gtaaagttta tattcctcac
    46261 acatataata caattaattc agttttaatt gtcattatgc tcaatattta gtttttctgt
    46321 atcttataaa ccaagaatat aattgataga gacaccaaaa attttagcaa atattattaa
    46381 ctcatcatct cttattggtc tttcatcaga ctctattata ttcataacac ttgtatttat
    46441 atttgttttt tcaaacaatt atttttgtga cctattcata ttttccctaa tatatttaat
    46501 cacttgactt atgttcatac atgatcacct cgaaaaattt ctattgtaga gttgtaaaaa
    46561 atttagcttt aaaatataga atatcaagtg attttaagta agaattgtaa caattaaata
    46621 agtataagac aagtttatga gttcatattt tataacaagg ggtgatgtta tgaaaatact
    46681 acaacaattt aaaccataca aatatgataa agaaaaaaat atagaatatg atgaaaaaat
    46741 tatagctaat caaaacacag aagtttatat agtatatcca cgtatatctg atgaagaaaa
    46801 taggagaaga tgggaagagt tcaatgaagt agctaaagaa gtagccatta atatagctat
    46861 gaagaaagtt gagacagtag aaagttaaga gaatagagaa gttgctaata cttagcactt
    46921 tctcatagaa gaaaattgga caactatttt taaataacta ggaataaaaa agttaaatca
    46981 tatttgaaaa aaggtgataa aattgttgag tattgttatt agtaataaga atgtattaac
    47041 tattaaaaga aactataagt ttttagtaaa tatagtattt aaggatatta taaactctgc
    47101 ctgtttttcg gggtctggat tgttccttgc attgtttatc gttgtctgca tttctactat
    47161 ggcttctgca acagaaatgc catgtgcacg ggcaacaatc tttaacaggt attttgtatc
    47221 tcgtttctta aatccaatca tatatatgac tcatttctta atttgaccat ttgcaaccat
    47281 aactcatggt gtgatttatt ttatgacacc cttataagag aaactataat aaatgagaat
    47341 gaataaaacc gtatcctgtt aatcacatgt ttaatgtgaa atacggttac ggtttttctt
    47401 cgttgaattt atagccaaca ccccaaacag tcaatatgta ctgtagatta tctgaggacg
    47461 gctctatttt ctatcttatt tcttaacttt cgtataaatg atgtcagatt gctaccctct
    47521 ggcgcattat tgaagctcca tatgttatca tatagttgtt atttcgtgaa taccattcct
    47581 ttatggcaaa agagaaaata catcaaatca aattctttag cagttatata tataatttcc
    47641 cctttttccc acctacttta tagcaaacaa atctaaatat tcttaagtaa cataatcttt
    47701 atataataca tattcctaat aacaatagcc agaaagcact taatgatgaa aaaaccctat
    47761 taactatgaa caatttttta atacctaaaa attctaagtt gccgataaaa agaccaattg
    47821 ctatgattat acctaaaagc ccaatccaat ttgctacata atttatagac agtaaactca
    47881 ttgaattaca gaaaatcata aaacttaaaa atacaaatgc aacatgctct gtcatggttt
    47941 cacctatata tgtgtttaat actttgtata attgtccagc ttctttttca gtaatctgtt
    48001 tatttatcat ctggttagac aacattggaa aggtctttgt atatctcaag attcctacga
    48061 atagaagaac tccgtagatt attccattga tatatgcaaa gtttgaccaa ataaattctc
    48121 ccttactttg ttcaataaaa cgtaatgcaa tagatgcctg gacaaccata aaaccaccaa
    48181 ttccaaatag atagaatagc aaagaaatca tagttttctt attctgcatt ctctttagaa
    48241 ttataatagg attttctcta ataattttag gataaccaaa actaaacatt aaacctatca
    48301 tacttccagc aatacaaaaa gctgataata ttgataaaac acctacaact atattcatat
    48361 tttcctcttt tctaaattat attttttaaa tatatcaaag taataaaact aacttattgt
    48421 cttaaaattt ctagaatatc tctcaatatg ccgttgaact tttctatctc ttcttgacta
    48481 cattttgata aaacttgata aatctgaatt ttcatattca tttcctgctc attgtgatta
    48541 tgataaattt gttctccaag agtagttaaa tagataggaa ttgtacatcc gttaccttgt
    48601 tctcgtcgca tttcaattaa atttttttct tgtaaatgtg caataatgac ggacattctt
    48661 ccttttgtta cacctacttc tttacatagt tctttttgca gaatacctgg catttttcca
    48721 atcattacaa gtgtatgaat ctctgcaata tataatttat catcagttcc ataggacttt
    48781 gaatttttat tacgttcaga agcccaattt aaaatctgta caaaagtatt aaatatctca
    48841 tgttcttcca tttttgttca cctctaaata cagtttaccc cgtaaactgt aagaggtcaa
    48901 gtcatatttg atagaacatt ctattattat aaaaaacatg taaataaggg ttactgctat
    48961 ttagatgtag aagtaaggtt ttatatttat cttactttaa catcttccag ttgctatctt
    49021 tgtgaatcct caactcaaac tgtgaaatct gtgtcacctt tgtctgatta tcaataaact
    49081 tcactgacaa gccgattttc attgttcgtg agtttttctg ttttattact tttttctcgt
    49141 tctctttttt cttgaacatg atttcaattc ctttctattg tttgatacgt cctgcaccta
    49201 ttaggtgctg ttgcaagtag gcactcgtaa ggtctgcata gccaatcgga ttgttcacat
    49261 ggtacatatg gttgttgcca atgtatattc cgatgtggct tatatagcta ccgttgttat
    49321 aagtagagtg gaaaaacatg aggttgtcag cttttgcctg taaaagcggg atgagctata
    49381 aaagagaaag attatttaaa agttgagaaa aatagtttct ttagttttat tcataacaat
    49441 tcatttaagg gttttatttc agcactacat gatgatgacg ttttagatag taaaagcttg
    49501 gacaaattag aagaatattt taaaaatttt caagaaaaat gtattgatga ctaataaagc
    49561 tatcagtatc tttttagttt gagaaaattg agaatagtgt tttgatttaa tgctagtgtt
    49621 atgtaatggt agaaaattat ataaagaaaa gtgcttattt ccttgtattt gatagtaaaa
    49681 aatttagaaa ataataccga ttaaaattta aagaaatata tgaaatacta caatagttta
    49741 aatcatgcaa atatgataaa taaattgaaa ttataaaagc tatataattt tagaagaaat
    49801 agttgacaga taaattgcct tactatatta ttgtattaaa tcattaatac aataatatag
    49861 taaggaggta atgaatgaaa tctaaaaaat acaatattac aaaaggatta tttatagttt
    49921 acataattat tttgacatgg ataatactat tcaagttaca atttgatgtt tcatccattg
    49981 aaaccatgaa tcttagaagc ataaacttag taccttttgc tgggtcactt ataattaata
    50041 ataaagtaga tatatcagag attatattaa atgtggctat atttatacca tttgggatat
    50101 acatatgtat gctaaaagaa gagtggagct ttataaaaaa agttatacct atttttataa
    50161 ctagtttggc atttgaaaca cttcaatata tatttgcact aggtgcaagt gatataaccg
    50221 atttgatagg aaatacacta ggaggaatca taggaatagc tgtttttatg ctattgtcga
    50281 aaatatttaa gaataatacc ataaaaatta ttaatatatt agcatttatt gtgacaatta
    50341 ttgttgtatt atttttaggc ttagttattt ttgcaaactt atagaaataa gtatataggt
    50401 ttaacttaaa atagagcgta aaatacagtt acatataaac ttatttacac ataagaagca
    50461 cctatataga catataagtg cttcttaaat tattaaagaa ttattgtatc ttgaaactct
    50521 tgtatattca attcttgatt ttctcttgtt ttttctaata aatctaacgc acaatttata
    50581 caaactttaa tttctgcatt ggtatttttt tcataataag ttatatattt gtttctatat
    50641 ttatctattt cttttccaca acgactacac attacaatta cgctcatagc ttagtacctc
    50701 catctctaat tattcttaat atattcaata gtatcacttt tctgaaaata atgattgtta
    50761 aaactgtatc aaatatagat ttacttttta ttataatgca ttttaataaa aaaataaagg
    50821 ttatgagtaa aatatttata gaaaaaagta tattattgaa ttgattataa agttttatta
    50881 tttttatcat tcttaaatac acattaatat ctataaaatg acaaaataaa atatactatt
    50941 taaatagata ttaaaaaatt gatgccaagt atttgtttgc tatatgaata acaatttatt
    51001 taggagcttt gatttgacac tgtataatga taacgtaatt gttaaaaaag tttgctgatt
    51061 tggatgtgtt tttagaaaat agaaaaatat atacttactg actaatgata attttatatg
    51121 tattttagtt tgagtgattt aagaaaagtg ttttgaaggg ggagtatttt atagagtaac
    51181 taaatatata taatagtaga aaataacata taaaaagtag tgtgtatttc attaccttct
    51241 ttatctgttc cgatagggtc ttgtagagat acttgagttt tatttttttt gttagaccta
    51301 atattcatta aaatttcatt ttcaatacat ctagaagcat atgttgctaa tcgagttcct
    51361 ttatctatgt tataagtttc tatagcttta attaatccta ttgtacctat agatattaaa
    51421 tcatcctggt cttctgttga attattatat ttctttgcta tataagctac taatctcatg
    51481 tttctttcaa ttaatgtatc ttttgcactt ttatcgtttt ctattttaaa tttagttaaa
    51541 tactcaatct cttcttcagg ggttaagggt ttttcaaaag atttaagagc tgccaatagg
    51601 tcaccccctt ttcaacggtc actttaaatt atatgaagga gacttatcca agttgcctgt
    51661 tatctaataa aataatatgc atatttttag aatttaaaac atatatttgc aaacttttag
    51721 atggaatatg acataaagag tgggaattta aatttaagtt tttgttgtat atatatgaaa
    51781 caaggcgaag gaattattga tttataaagt ataaattgaa actgaggtgt caataaatat
    51841 aaaggaaata gtatttatgt atgttttgat gttgaggtaa aaaattaatg aaaaacatta
    51901 gaatctataa aaaatatgaa tataggaggt gtaattttgc aataattaaa aaagtaaatg
    51961 caattaatta tttggataaa gttgattgca agtaaaaagt attagtcata gttaatactg
    52021 ttaagggtga aggtggtgtg ttaatctgta tgtgtgtagg aagagttttg agttataatg
    52081 aaaaaactta taaaaggtat ttatgaaaaa cttatagtta accatctata tataaaatat
    52141 tatttagggg ttgtttttat tattgaaaat aagaaagcgt ggttttatat caatcgaatg
    52201 tgtaataagt attgctatat tatatgtggc tgtttattta gtttctacat cattgtatag
    52261 ttgttatagt tttgtcagta gaaatatatc tgacagaaaa atgttaagta ctgcaaaaaa
    52321 atatatagaa gatgagaagt atagaataca aaatagtaag tatgagttaa ttgaaaataa
    52381 gatagaaaaa aattacataa atggatatga aattagcagt agagtagagc aaattttaga
    52441 ttattatcaa tgctatgaaa taaatataga gataaaaaat gaatttaaaa aattgaggtt
    52501 taatagctat gttactagaa aataaaggct ccatattaat aataacattg ataatattct
    52561 ctattataag tactgtgtgt attatgtgta taggtttaat ttatacacat aataatatgt
    52621 ttaagttagg atacaaggac attcaactaa aagaaatttc tttaagtgga atagaaatat
    52681 cagtaagtaa tgtactttct tgtgttgagg aagctattga tatatctaat agtgaaggtg
    52741 aatttagaga atatttctta ggaaataaca tgattgaatg tataaaaaaa ataaaagata
    52801 cttcttatag tagcgtagaa ggactttctt taaaagtaga aaataatact atttatgata
    52861 gagaagactt ttttgaattt gatatagaaa gtagtgttag agaaaaagaa tttttaaaaa
    52921 caataaaagt aagagtgaaa attaaaaatc catgggtagg aattgacatt gaagattata
    52981 tgaataaatc taataacaat aaaatttatg acaaaaaatt taataattat aaagcatctg
    53041 aaaataatga aattctaaat caatttaaaa atgaaagtga aaatataagt aatcaagagg
    53101 ttgttgaacc tacagaagaa gacaatgagg aatatgaaga agaacttaaa caaaacataa
    53161 ttgaaaatat aaaaaagaat tttgatgaaa aaaaactagt acaggtatat aagtataggg
    53221 gtgtataact ttgaaaaaag aaggaatgtg actgtgatag aattaatagt atctattagt
    53281 ataatactct tgatagttac attatctttt ccaaaagata atattgaaaa tcataaaata
    53341 aatttatttg cacgtcaact ttgttcagat ataaggtatg ttaggcgaat taatatgttt
    53401 agtaactaca atacatatat atactatata aatcaaggta aacatgaagg ttatgtattg
    53461 agaaaagatg gtaaaaatat taagtcaata atactgccta aaaatgtaaa aatagctaga
    53521 agtattgaaa caataaagtt taaatctgat gggtcacctc aaaaggcatc tacaatagag
    53581 atatataata atagattaag aaaaattata acaataacac ctgtaagtgg aagagtactt
    53641 ctgaaagagg gaaaatatga aacataaata tggttactta cttttggaaa gtgtagtatc
    53701 attgtcctca atgttgataa tgatactagt tttatattct atatttttgt ctacaataag
    53761 cttaaaatta aaagtagaag ataagataga actacaacaa caaagtcttg aaatcataaa
    53821 atctatggaa ggaattatta gcaattctat gggaataata aatgtatcta attatgaaga
    53881 cacatttaaa aaggcaacat ctataaaatg tagatatgta gatgaaaatg taaataataa
    53941 tgaagaaagc ataagcaata aagaaattat attgaatgaa agacgaaata agttatttgt
    54001 aaattcttta aatggcgaaa gtagtcaagc aggtggttat gaaataggag attatgtaga
    54061 tgagatgtat gtatcaatca ataataatgg ccaatatgtt aatattaaat tgaaattatc
    54121 aaaacgtagt caaaaatatg agactgagtt taaaataaaa gtatggaatt ttagtgaaaa
    54181 tatataaaaa tacataaatt tatagagaaa gaaataatat caataagtca tataaaatat
    54241 aattattgag aactatataa ataaataata tcaatatgta aagtgcatag attaagaata
    54301 tagaggataa taataaaaat atagaataag taatttgcca aatacttgtt tatattgtat
    54361 aacttatgat attatgatat tagtaaaaat ttgtaatcct gacttgacag aattcaagta
    54421 agagatataa ttttaaaggc atagtaatgt aaaatttact aaaaaataag aaatttattt
    54481 taatatggag gaacaaaaaa tggtatcagc aggtgatttt agaaaaggtg ttacatttga
    54541 aaaagatgga caaccatgtt tagtagttga ttttcaacac gttaagccag gtaaaggagc
    54601 tgctttcgtt agaactaaat acaaaaactt aaaaacagga gctataagag aagaaagttt
    54661 caatccaagt gaaaaattcc ctaaggctgt tatagataca agacaaatgc aatatctata
    54721 caatgatggt gagttatatt attttatgga tcaagaaaat tttgaacaaa taccattaaa
    54781 ttatgatcaa gttgaagatg caattaagtt cttaaaagaa aatgaagttg ctacaataag
    54841 attttaccaa ggacaaccat tccaagtgga agctccaaac tttgcagagc tagaagttac
    54901 agatacagag ccaggtataa aaggtgatac agcaagtaat gtaactaaag cagctacagt
    54961 tgaaactggg gcagtcgttc aagttccatt atttataaat actggagata aagtaaagat
    55021 agatactaga acaggtgaat atttatcaag agtataaaaa tttatgtata taaaagctta
    55081 tatgtcttaa taatataaga tatatgagct tttagtttat atataaaaaa gaaagcgagg
    55141 ggtgttacat gaaacattta tatgaagaag ttgcatactt aaaaggccta gcagaaggac
    55201 tagaaataag tgctgaaagt aaagaaggga aaatgataca taaaatagtt gatgcattag
    55261 aagtatttgc agaggctatt gtaacattgg atgaagaaca agaagaactt caagattttg
    55321 ttgaatctat agatgaagat ttagcagatt tagaagaaga tattgctgac atggaagaag
    55381 atctttatga agaagatgac gatgaggatg atgaggactt cagctatata gaaatggaat
    55441 gcccaaattg tggagagtta gtagaaatag acgaagattt gttatatgat gatgaagtag
    55501 atgttgtttg tcctgattgt aaggctgtga tattatcatc agaagatgat tgtgatgatg
    55561 attgtacatg tggtggttgt tcaagttgtg atgatagaga gtaaaaattc ataagaatta
    55621 aaactgccta tgatgcctat gagatatttt gcttcatagg tagttttatt tttatgagga
    55681 aggtattatg tattttggtt ttgcaatact tggacaaaaa tagtacacta gaatttatag
    55741 aataggattt tggagggatg taaatatgaa aataagtaaa aaattgctag ataatataca
    55801 aagatttgaa aatgttataa attataaatt taaaaataaa gaatatatac tagaagctct
    55861 tactcatagt tcatattcta atgaaaataa aaaatataat tttaacgaaa ggttggaatt
    55921 tttaggagat tcggttttag gcatagtgat aagtgattat ttgtttaacg aagaagctaa
    55981 tctgcccgaa ggggaactaa ctaaacttag agcaaatata gtttgtgaag attcgttaag
    56041 tgaagtagct aatgatataa atttaggtgt gcacatgtta ttaggtagag gagaagaagc
    56101 aacaggagga agacatagga cttcaatatt agcagatgca tttgaagctg taatagctgc
    56161 tatatatctt gatggaggat ttgaaagtgc aagacagttt atacttcatc atatggaaaa
    56221 tataatttat gattcaagaa aaggaaatat atttagagac tacaaaacgc atcttcaaga
    56281 agtgttacaa gggaatggag aaaataatat ctggtacagg cttatagaag aaaaaggacc
    56341 agaccataat aaaagatttg taatggaagt tggaattaat gaagatgtat tgggtatagg
    56401 agaaggcaaa agtaaaaaag aagctgaaca gttggctgct aaaatagctt taaagaaaaa
    56461 attatgggaa aaataaatat aatatgtaaa aatataaaaa gaaataatta tattagaagg
    56521 atgttgtaga tgaaaaagag aattatacct atatttgttc ctcacaaggg atgtcctcat
    56581 gattgcatat tttgtaatca aaaaaaaata acaggtgtga gtactgatgt tactagtgaa
    56641 gatgcaagaa atataattga agaatgttta gagactatag ataaagatgc agatgtagaa
    56701 atagcatttt ttggtggtag ctttactgct atagatattg atatacaaaa aagtttatta
    56761 tcagttgcta aagaatatgt agaaaaaggt cttgtaaaag atattagaat gtctacaaga
    56821 ccagattgta ttgatgaaga tatattaagt atgctaaaag aatataagac aagtataatt
    56881 gaactaggag tacaatcttt agatgaaaaa gtattattag atagtataag aggtcatcaa
    56941 tctgaaattg tatacaagag ttcaaagatg ataaaaaata gtggaattaa actcggatta
    57001 cagatgatga ttggtcttcc aactgataca gaagaaaagt gtatatttac agcaaaaaaa
    57061 tttgtagagc taaaaccaga ttgtgttaga gtttatccaa ctttggtagt aaaagacaca
    57121 ggacttgaaa agttaatgga acaaaataaa tatagtccat ttactcttga agagagtgta
    57181 aacatagtaa aaaaagttct tgcactgttt tatgttaata atattaatgt aataagagtt
    57241 gggcttcaag ctactgatga tatacaaatt ggaaaagctg ttttagcagg accatatcat
    57301 cctgcattta gagagttagt agaagctgat atgataaaag attatttaga atttgttatt
    57361 ttgcaaaata aaaatataaa gcagatgttg gtcaaatcta ataaaaagaa tatttctaaa
    57421 atcataggaa ataaaaaaac aaatgttaaa tatatggaag aaaaacttgg tgtgatttta
    57481 aaaacacaag aatcagattt agatataaat caattagaaa ttgtgttaga tggaaaaagt
    57541 ttaattagtg ctaatatgag agacattcat agaaaattgt atgacattta tgacctttag
    57601 ttttaataat gaagggagag aaaagatttg tatttaaaaa gactagagtt aaagggattt
    57661 aaatcctttc cagtaaaaac agatattatt tttaaagaag gaataacagc catagtagga
    57721 ccaaatggga gtggaaaaag taatatatct gatgctgtaa gatgggtatt aggagaacag
    57781 agtattaaga gccttagagg tgataaactc gaagatgtaa tatttgcagg tacagataca
    57841 aaaaaaccta tgaattattg tgaagtggct cttactattg ataattctga aaatcaattg
    57901 gaattagatt ttacagaagt aactataaga agaagggctt atagaaatgg tgaaagtgaa
    57961 ttttttctaa ataataaaag ttgcagatta aaagatataa aagaagtctt tttagatact
    58021 ggtattggaa aagatggtta ttcaatcata gaacaaggaa aagtagatga aatattaagt
    58081 aataatcctt taagcagaag aaaagttttt gatgaagctt gtggcatatc aaaatataga
    58141 tataaaaaac aggaagcaga aaggaattta agcaatacaa aggaaaattt agaaagaata
    58201 gatgatatat atatagaaat tgaaaatcaa ttaaaacctc tttttaatca acaaaccaag
    58261 gcaaaaaaat acttagaaat aagtgaaaaa ttaaaaatac ttgaagtaaa tagctttata
    58321 agagaaattg aaggaataga aaaagaatta agtgaggtta atgaacatcg taaggttatt
    58381 gaaaaggaac tcaatgaaaa agaagaacaa aaaaatgttg tagagaaaaa gcaagaagat
    58441 attaataaag aggtagaggt attacaggat gtaattgaaa aatctgtaga ttatataaat
    58501 tcaatcaaag gagttatatc aaaaaaagag tcccaaataa atttaattaa ggaaagaata
    58561 agaaatttta cgaatgaaat tagtagaaaa aatttagaaa taaatgatat aaaagagaaa
    58621 ctaaatgaaa ataagcaata cataaaagaa ttagaaaata ataaattatc aagtagtgga
    58681 gaactatctg ccttgcagga aaatataaaa gtattggaag caagtaaaga taaacaaaaa
    58741 attaagttag aatccctaaa taatgagata gaattattga aagaaagtat aattgatata
    58801 ttaaataaga aacaagagtt tagtaataag ttgtccactt taaacgcaaa taaagaaaat
    58861 atgaatgtta gagatgaaaa tataaatttg gagataacag aactaaacaa aaatattgat
    58921 ataaaatcat ctgaattaga tactataaat aaagagttta atatgcaaaa tgaaaattta
    58981 aagaatgtaa ataataggca taaagaatta tcaactaatt tgcaagattc aattagtgag
    59041 cacagtaaac tagaagatga aatacagaaa agtaaatata atctaaatgg atataattca
    59101 aaattaaatg tctatataga tatggaaaat cattatgaag gatttaatag aggagtaaaa
    59161 gaagtactaa aaaataaaaa tttaaaaggt gtacatggag cattaggaca aattataaat
    59221 gtacctgaaa aatatgagaa atctatagaa gcagcacttg gtgcttatat gcaaaatatt
    59281 ataactgata atgagtttag tgctaagtct gcaataaact atctaaaaca gaataatttg
    59341 ggtagagtaa catttcttcc attaaatata attaaatcaa ataaaataag cctaggaaat
    59401 ctaaaagcaa atactaagtt cataggaata gcaagtgatt taattacatt tgatgaaaaa
    59461 tatagaaata taattgaaaa tatacttgga agaacaatac ttataaataa tatagatgag
    59521 gggataaaat ttgcaaaaga aactggacat aggtttaaaa tagtaacttt agatggtgaa
    59581 atcttaaatc caggaggttc tttgactgga ggaagtctaa agactaatgg gaatatacta
    59641 tcaagaaaaa gatacattaa tgaatataca gaaaagataa ataatatcaa gcatgaaatt
    59701 tcacaattag aattaaaaag agaatctcta gataaagata taaaaaatat aaagagtgaa
    59761 attgattcac atgaaagtaa aataaaagat ttagaaaaaa gtataataat aaaaagtaca
    59821 agcatagaga atattgaatc tgaaattgaa tcgttaaaag gtagtattac taaattagag
    59881 aatgagaaaa atgatttaaa ttctaaccta aattatacac ttgaaaaaag agataatgtt
    59941 agaaaagata tagaagagtt agataattta tacaatcaaa ataaagaaaa aattgatgca
    60001 ttgaatgagg aaataaaaag atacaatgat ttatatgata aagaaaaatc tgaatttgat
    60061 gaattaaact taagcttagt gaagaaaaca gaagcttaca atagtatagt tagagatata
    60121 aaaagaatat ctggtgaaaa ttatgagcta gaagaaaaga ataaacaatt agaagagtca
    60181 ttaaactatg aagaacagga aataattaaa ttacaagatt ctatagctac tgaagaaaaa
    60241 gaaaaagaaa atctaacaaa acaactagga gatagtaata gaaatcttga aactagaaaa
    60301 atagcaaaag atgatttgaa aaatagtttt gatgaaatta ataaagaatt aaaaactata
    60361 gatagacagc atatagagct taaagaaagt ttatttaaag ttggtggaag attagaaaga
    60421 ttaaaaacta gtcaagacac atatataaat aagttgtttg agcaatatga tatgacttta
    60481 gtacaagcat tggaaattaa agatgaagat ttggatatag atagaaaatt cttagaaagt
    60541 ctaaagagag aaataagaaa tcttggaaat ataaatatag actctataaa ggaatatgag
    60601 gaaataaaag aaagatacga tttttatagt gaacaaaagc aagatttaga agagtctatg
    60661 gaagagatag aaaaacttat acatacttta gaagaaaata tgaaatctga atttgaaatt
    60721 aagtttgaag aaataagtaa aaattttaaa tatgtatata agagattatt tggtggtggt
    60781 tgtggagaat taactatctt agataaagaa aatttattag aaagtgatat actaataaca
    60841 gctcaacccc caggtaaaaa aatgaaaaat ttaaacctct tatctggtgg agaaaaagct
    60901 ttaacggcaa taagtatatt atttgctata ttgattacaa agccaacacc gttttgtata
    60961 ttagacgaga ttgaagctcc acttgatgat gcaaatatat ttagatttgg agagtttttg
    61021 aaggatttat ctaaagagac tcaatttata tcagtaactc ataggagagg aactatggaa
    61081 gctgctgatt atatctatgg agttacaatg caagaaaaag ccatttcaaa agttattagt
    61141 ttaaaattaa aagaagctaa ggaaataacc gatattatat aacttagatt gacataggag
    61201 gaataacagt gttaaaaaaa ttatttggtt ttggaaaaga caaggaaaag gaaatagaaa
    61261 agaaagatga agaagaagta gtagacagtg ttgatagtct agaaaacttg gaagaaacca
    61321 ttttttcagg acttgaagaa gaagtgatag ataaagacga agatattgaa gaaaaaactg
    61381 aggaaagtgt caataatgaa ggcactgaag aaatcgaaaa ctttgaaaaa atagacgttg
    61441 aaatggatag tgatggaaaa gaagtagaaa atatttcaga taatgattct caagaagaga
    61501 taatcgaaga attagaaaat tatgatgaaa ttgagtctaa agagatagaa gctaaagaag
    61561 aaaagaaagt taacttgttt gaaagactaa aacaaggatt gacaaaagca aagcaaggaa
    61621 taactgatag aatagatgag gttttaaaat catatacaaa aatagatgaa gaattacttg
    61681 aagatttaga ggaaatttta ataacagcag atgttggtgt aaatacaact atggatataa
    61741 ttgaaagact aagagataaa ataaagcaaa aaggtattat tgaaccaatc aaggtaagag
    61801 aagaacttaa atctatagtt gaagatattc ttacaaatga aaactctaca ctagatatag
    61861 aaccagcacc atgtataata ttaatggtgg gtgtaaatgg ggtcggtaag actactacaa
    61921 taggtaagct agcaaataga tacaaaaaag atggtaaaaa agttttatta gcagcagcag
    61981 atacatttag agctgcagca acagagcaat tagaaatttg ggcaaataga accaatgtag
    62041 acataataaa acaccaagaa ggagcagacc ccggagctgt agtatttgat gctataaaag
    62101 ccgcaaaagc tagaaaaaca gatgtattaa tatgtgatac agcagggaga ttacacaata
    62161 aggctaatct tatgaatgaa cttggaaaag tatttaaaat agtggataga gaatttccag
    62221 aagcaaagcg tgaagtactt cttgtggtag atgctacaac aggtcaaaat gcagttattc
    62281 aagcaaaaac ctttaaagaa gttgcagata taacaggtat agtacttaca aaacttgatg
    62341 gaactgcaaa aggtggcgta gtgcttgcag taaaatcaga agtagatgtg cctgtaaaac
    62401 ttattggagt tggagaaagt gtggaagacc tacaagattt caatgcaaaa tcattttcag
    62461 atgcattatt tggtaactag tgttctttta aaaataatgg ttgacaagag tgtttttatg
    62521 atataaaata caatagtgta aagtaaataa cctttacagt atactgctag gaagtgtaag
    62581 atatgaatat agaaaaaatg gtcgaaatag gattgttatt tgaacagtat aaagaattat
    62641 taactgacaa gcagaaagaa atagttgctc tatactatga agaagattat tctttaggtg
    62701 aaattagtga gaatctgaat gtatcaagac aaggtgtgta tgatacctta aagcgttcag
    62761 aaaaaatact aagagattat gaagagaagt tacacttagt atcaaagatt caagagcagg
    62821 aaaaaaatat taagattata aaagataaaa ttattgacat taaagaagat ttattgcaca
    62881 atagagattg tgctaattta atccctaagc tagaaaatat agaagatgta tgtagggaga
    62941 tgataaaatg atatttgaag gattgtctga taaactacaa ggggcattta gtaagttaaa
    63001 atctaaagga aaacttacag aagcagatgt aaaaaatgct atgagagaag ttaaacttgc
    63061 tcttcttgag gcagatgtta actttaaagt agttaaagat ttcataaaaa aagttcaaga
    63121 gagatgtgtt ggacaagaag ttatgcaaag cttaactcca gctcagcatg ttatcaaaat
    63181 tgtaaatgaa gagcttacaa gtctaatggg agatgtacaa agtaaagtaa tgatttcctc
    63241 aaagcctcct acaattttaa tgatggttgg attgcagggt gcaggtaaga ctactacagc
    63301 aggaaaactt ggaggatatt ttaaaaagca aggtaaaaaa cctctattag tagcttgtga
    63361 tatttataga ccagcagcta taaaacaact tcaagttgtt ggagaaaaat tggatatacc
    63421 tgtattcaat atgggagaca aagaaaatcc agtaaatatt gcaaaagcag gtttaagcca
    63481 tgcaattaaa aacgctaatg atttagttat tatagataca gctggtagac ttcatataga
    63541 tgaagtactt atggatgagt taaagtctat taaatcagaa gttaagccac atgagatact
    63601 tttagttgta gattctatga caggtcaaga tgctgtaaat gttgcagaaa gcttcaatga
    63661 ggcacttggt gttgatggag tagtattaac taaattggat ggagatacta gaggtggtgc
    63721 tgcactttca ataagagcag ttacacaaaa gcctataaaa tttatgggga tgggagaaaa
    63781 gctagatgat atagaacctt tccacccaga tagaatggca tcgagaatat taggtatggg
    63841 agatgtctta agcttaatag aaaaagcgca agaaaacata gacttagaga aagctaagga
    63901 attagagcaa aaaattaaaa aacaagagct tgattttgaa gatttcttac aacaaatgga
    63961 acaaatacaa aatatgggac ctcttgacaa gatacttggt atgatacctg gtatgggaaa
    64021 tgtaaaagac caacttggag atgtagattt gaatggtaaa gaaatgaaga gaacaaaagc
    64081 cataattcag tcaatgacta catatgagag acgaaaccca ggagtattaa atgcttcaag
    64141 aaagaaaaga atagctagag gcagtggaac cagtgtacaa gatgtaaata gacttataaa
    64201 acaacttaat gaaatgaaaa aaatgatgaa gatgtttgct ggttcgcaaa agagtatgaa
    64261 gaaaaggggc ggcttaggcg gtttaccttt ttttaaataa aatataaaaa agtaaaaatt
    64321 attcggaggt gactgtaatg gcagttaaaa taagattaaa aagaatggga gctaataaaa
    64381 aacctttcta cagaatagta gtagctgatt caagagctcc aagagatgga aaatttatag
    64441 aagaaatagg atactataat ccaatttctg agcctaaaca agtaagaata aacgatgaaa
    64501 aagctataaa atggttagct actggtgctc agccaacaga agtagttaaa aaattacttg
    64561 taaaaaacgg agtaatagaa aaattcgaag cttctaaaca agcaaaataa ttttttcttg
    64621 gcaatcagtt taagtaagta ctcattgcta aggttacttt aggagatgaa atatatgaaa
    64681 gagctagttg tagatatagc taaggctcta gttgataatc ctgactcagt tgttgttgag
    64741 gaatttgaag ataatgacgg tatcgtttta aagcttacag ttgctcaaga agatatgggt
    64801 aaggttattg ggaagcaggg aagaatagct aaagctataa gaactgttgt aagatctgtt
    64861 gcaaatagag aaaatataaa agtttctctt gagatagtat aaaataggag gattaggtat
    64921 aatgcctagt cctttttata taaatttgta ctttaagatt ttatgatgat atgaccacat
    64981 aagattaaat tttttaagaa ggtgataaca tgaaagaaaa attaactcat tttaaggtag
    65041 gtcaaatagt aaatacacaa ggtctaaaag gtgaggtaag agtttatcca cttactgatg
    65101 atatagagag gtttgatgaa ttaaaagatt tctatttggg aaaagattta aataataaat
    65161 tgtctgttga aaaagtaaga tacaaaggtt ctatggttat aatgaagata aaaggtatag
    65221 atagcataga gaaagcagaa aaactaaaaa ataaatttat gtatgtatct agagaagata
    65281 gcagagagct tgaagaaggc gaatttttta tagcagatat gattggaata gaagttttaa
    65341 ccgtagatgg aaaatatgta ggaatattag aagatgttct tcagtattca gcaaatgatg
    65401 tttatgtagt aaaaggtgag gaagataaag aatttatgat accagctata aaaaaatttg
    65461 tacctacaat agatattgat gaaagaaaaa tgattataga ccctattaag ggaatgatag
    65521 attaggtggt aatatgagat ttcatataat gacacttttt ccagaaatat ttaattcgta
    65581 tatggatgaa agtataatga agagagcagt tgaaaaaggt ataattgagg ttcatatata
    65641 taatataagg gatttttcta ataataaaca taaaaaagta gatgattatc catttggagg
    65701 aggagctgga atggtaatga ctcctcaacc tatatatgac acgtataagc atataataac
    65761 aactcataat ataaataatc caagtgtaat ttatcttact ccaaaaggta aggtatacaa
    65821 tcaatctata gcaaagcata tgtctttaaa agaagatata atactgttat gtggtcatta
    65881 tgaaggaata gatgagagaa tcattgattt aatagttact gatgaaattt ctattggaga
    65941 ttatgtatta actggaggag agctcccagc acttataatg atagattcta tatcaaggtt
    66001 aataccaggt gtattaaacc aagaagaatc atttgaagaa gaatcattta aagataattt
    66061 attggaatat cctcattaca ctagacctag agattttgaa ggattaaaag taccagaagt
    66121 gcttttatca gggaaccata aaaagataga tgaatggaga agagaagaat ctataagaat
    66181 aaccaaagaa agacgatttg atttatataa aaagtctaat gaaaaataaa aatataataa
    66241 atatgtatac aataaagtac ctataaatgg aattaaaaac ataaaagtgc ttgtaataac
    66301 tattgaagta tagtataata taaaatgttg aaaatacggg cgttcctctg tttacactgg
    66361 tcgggtagtt aagaacgtct atgatatcta ggaggaagaa agatgaatga aatgctaaga
    66421 gcaattgagc aagaacaatt aaaaaatgaa gttcctaatt ttggacctgg ggacacagtt
    66481 aaagtacacg ttagaattat agaaggaaaa agagaaagaa tacaagtatt cgaaggtgta
    66541 gtattaaaga gacaaggtgg aggagcaaga gaaactttca cagttagaaa aatgtctttc
    66601 aatgttggtg tagaaagaac tttcccagtt cactctccaa aaatagaaaa aatagaagtt
    66661 actagaaaag gtaaagtaag aagagctaaa ctaaactact taagaggtag agtaggtaaa
    66721 gctgctaaga taaaagaagc tagaaataaa taattaaaaa ctttacttat aaatgggggg
    66781 ctgatttatc agtcctcttt ctattttaat gaaaattaca gcaaataatt atactaaaaa
    66841 taaatagaaa tatttgttga aaatatacat tatttatcta tgaatttata acttttaaaa
    66901 tgaaaaataa aattggtaaa tattgcattg tattttgtaa caatattaaa aataagagta
    66961 cagtattttg taaagtatga cgttaaaaag atgacaatat tatagtttgt gaagatatat
    67021 ttttttagtg aaattaggat ataataatat aatatttaat aaggagtgat acatatgtca
    67081 aatgaatatg aagagtatct tatggatgac aatctacata taaactggta tccaggtcat
    67141 atgaaaaaaa ctaaggagtt agtaaaaaac aacttaaaat tgattgatgt agtaattgaa
    67201 cttttggatg ctagaatacc gtttagtagt aaaaatccag atatagacag gcttgtagga
    67261 gataagccaa gagttgttgt acttaataag agtgacatgg cagataagga taaattgaat
    67321 caatggattg aatactataa aaaaattaat ataaaagcta tacctgtaga tacaataaaa
    67381 ggtgttggta taaataagat aatcgaagaa tgtaagaatg taactagaga aaaaatgagt
    67441 tctttaaaag ataaaggtag aaaagaaaga gctatacgaa taatgatagt tggggttcca
    67501 aatgttggta aatcttctct tataaacaaa ttaacaggta gaaaaagtac gcaaactgga
    67561 gataaaccag gagtaacaaa agggaaacaa tgggttagat taaagggaaa tcttgaactt
    67621 ttagatacac ctggaatact ttggcctaag tttgaagacc aagaagttgc attaaattta
    67681 gcatttagca gagctataaa ggatgagatt ttagatactg agactttggc tttaaaactt
    67741 atagaaaaac ttatgaaaat agaacctgag aagttgaaag ccagatataa gctagactgt
    67801 ctaggagaaa ctccaattga aactatggat atgattggtc ataaaagagg gtttataaca
    67861 ggtaaaaaag aactagatta tacacgtata gccacaactg tattgaatga atttagagac
    67921 gggaaaatag gaaatataac attggaaatt ccagaaaacg ttaaaagata aattttaaaa
    67981 caaaatcaaa aatttaatgt taaaaattta aaaaagccct tccagaaagg cttttttatt
    68041 tttttgaaat atagacaagt atttctgtat aaaagtataa attaggttag aaaaccttta
    68101 aaaatattaa tttaagacaa atatatctaa tattttgaaa attaaaatga gtgtgattat
    68161 ttaaaatctt ggcatattga cttgcttgtt tcgtataata tataataagc acaaataaat
    68221 acaatatatt aaaaatttaa tttatttaat tttattaatt taataatgag ttcttattgt
    68281 ttaatttaac ttatttatgc aaacgtaaac aatcgagata ttttattaat ttaataaggt
    68341 taaaaagggg gattttataa tgggtaagac caaggatatc atagtatttg gatttgcgtt
    68401 atttgcaatg ttctttggag caggtaactt aatatttcca ccttacttgg gaataattac
    68461 aggtccagaa tggttaattg ccttcttagg atttacattt gctgatgctg gattggcact
    68521 tctagcagta atggctacag ctaaattcga tggaaacgta gttgaaatgt ttaaaagatg
    68581 tggtatgaaa ttagggattc ttataggttg tgcagatatt ttatgtatag gaccattctt
    68641 agctatacca agaactggtg caacaactta tgaaatgggt ataatgcctt tatttggaac
    68701 ttcaattcca gtgttattat tctgtatact tttttttgcg atttcatatg tactaacaat
    68761 aaaaccttct aaggtcgtag atatagttgg acagttttta actccagctc ttctaatagc
    68821 tttagcattt ataattataa aaggtattat atcacctctt ggagatatag tagataaacc
    68881 tatgatacct aatgtatttg cagaaggtat aggtcaagga tatcagacaa tggatgcttt
    68941 tgcagcaata gcacttgcat cagtactaat agtatcttta aatgataaag gatattctac
    69001 tattagtgac aagttaaaaa tgattggtaa agctggtgtt cttgcttgtg gaggattagc
    69061 tctagtttat ggaggattat gtttccttgg ggcaactgta tcaacaatgt atggaacaga
    69121 tgcagtacaa tcacaagtaa tagtaaatat aactgaaggg ttacttggaa atgttgggaa
    69181 agtgatttta gcagtagtag tttcattagc atgtttgaca acatctatag gtcttacatc
    69241 tgctacaggt caatatttct ctagactcac aaaaggaaag ttgagttatg aaaaaatagt
    69301 attagctgta tctgtattca gtgcagtagt agcatctttt ggtgttggaa ctataataaa
    69361 gatagcatct cctatactaa gtatagttta tccaccatca attgttttaa taattttagc
    69421 tttcttcaat gaaaaaatta agaatgataa tgtgtacaaa ggagctgtat atatgtcatt
    69481 gcttgtaagt atactaacag ttatatctag ttatggagta gctgttccag tagtaaattc
    69541 tttacctctt cattcattag gatttaactg ggtggtgcca gttataatag ctggaataat
    69601 tggtaatttt ataccatcaa agagtcaatc taacacactt ggaacaaact aagttttgtt
    69661 taattaaaat ctaaaagtaa aaggagttat ttgtataaat aactcctttt acttttagat
    69721 tttat
//
LOCUS       DAMKOJ010000007        69257 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000007 DAMKOJ010000000
VERSION     DAMKOJ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.007"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(282..2240)
                     /locus_tag="PC592_000569"
     CDS             complement(282..2240)
                     /locus_tag="PC592_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2075 domain-containing protein"
                     /protein_id="HDF4054587.1"
                     /translation="MKRAYYSSSVNEFIGKDIFTIFGEITCNDQFEANDLQKNTWKKE
                     IEILKRELSTFKDGHLLFEYTIPRIGSRIDNVLIYKGIVFLLEFKVDEDTYPRYAIEQ
                     VTDYALDLNCFHKESHDKLLVPILICTKAPQRNQRIRLMKENILETYCSNEFNIGKYI
                     EEVCTTYNKSSFNPDAWMDSLYMPTPTIIEAAQALYMGHNVEDISRNDASAKNLNQTT
                     KAINKIIDYSKIHNKKSICFITGVPGAGKTLAGLNIAIERQKVDENEHAVFLSGNGPL
                     VDVLQEALARDDVTRNGTRKTEAIRKAKEFIQIIHHFRDEAISVDTPPIERVTIFDEA
                     QRAWDEPNLTNFMKRKKGVLDFNMSEPEFLISILNRHIGWATIVCLIGGGQEINKGES
                     DGISGWFASLRNNYSDWDVYISNKIIDEEYSKGNSFDELTEGVNYRIIDDLHLSVSLR
                     SFRSEKVAAFVKAVLDVDKIAANELYNQFKKDYPICVTRDLELAKKWVRDKSKGSQRY
                     GMTASSGAKRLRKYGVWVQSKVDAKNWFLNGKDDVRASYFLEETATEFDIQGLELDWT
                     IVCWDGNLRFKNEQFEYYNFNGTKWQNINKEDNILYLKNAYRVLLTRARQGFVIFVPT
                     GDESDITMQPSFYNGVYEYLKEIGIEEI"
     gene            complement(2922..3254)
                     /locus_tag="PC592_000570"
     CDS             complement(2922..3254)
                     /locus_tag="PC592_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HDF4054588.1"
                     /translation="MYVLLSKYFTQKELAKKQLLNYTALLSFEIDAKDVNDIKKFVNK
                     LDLFKIGVSWGGHESLVFAPNIAILNEMTLEQAKALNVSPYTIRISLGLENSEDLIND
                     LNDALSIL"
     gene            complement(3233..3717)
                     /locus_tag="PC592_000571"
                     /pseudo
     CDS             complement(3233..3717)
                     /locus_tag="PC592_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895448.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
     gene            complement(3698..4210)
                     /locus_tag="PC592_000572"
     CDS             complement(3698..4210)
                     /locus_tag="PC592_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054589.1"
                     /translation="MKRLVAELTKEYLNKSMCYKEIMDCYIILIFYELLEIHKTKNEK
                     TLTSDSKINIDNIAEMMKYIEGNYAQTTLREVAKKFHFHPNYLSTLIKKTTGKSFKDI
                     IHEQRLKKATTLLKSTDMSIEDISIEVGYNNQTFFYKKFKETYSLTPKKYRIKSRILL
                     KEVSHETIYS"
     gene            complement(4294..4761)
                     /locus_tag="PC592_000573"
     CDS             complement(4294..4761)
                     /locus_tag="PC592_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HDF4054590.1"
                     /translation="MKDKTLEDILKQKTQAERYILECIDTNNVKKLDNKKIMSILHTI
                     LCWEEVNGTIVLTDKNILSLDEDIMVSKHHRFIDIPKHKHNFIELIYVYSGSCTQIID
                     GKETILKEGEICLLDMNVEHSINAVKENDIIINCIMRREYFDASFFLEFRLMS"
     gene            4947..5267
                     /gene="rhaM"
                     /locus_tag="PC592_000574"
     CDS             4947..5267
                     /gene="rhaM"
                     /locus_tag="PC592_000574"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDF4054591.1"
                     /translation="MNTVHKCFKMKLFKGFENEYKKRHDELWSEMIDMIHEYGGSNYS
                     IFLDEETNYLYGYIELKDAKLWDKSSETAICKKWWNYMSDIMETNEDNSPISIELKSM
                     FYLK"
     gene            6205..6780
                     /locus_tag="PC592_000575"
     CDS             6205..6780
                     /locus_tag="PC592_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4054592.1"
                     /translation="MSKIIAFVGSPRKNGNVDTIINEIIKGANKNKVDVKKYYLNDMN
                     IKGCQGCLYCRKNHSCSLKDDMIQVYEDIKKAEYVIIGSPVYICQVSAQTKLLLDRLY
                     PLTTIDKGKHIPRFGNKRIIMVYTQAAPLPIFFKRYFRYTSKHLKGMGLNHYKTIIAT
                     KAFEKNSIENNPKILKKAYNLGFKISKDINV"
     gene            complement(7450..7617)
                     /locus_tag="PC592_000576"
     CDS             complement(7450..7617)
                     /locus_tag="PC592_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054593.1"
                     /translation="MNWKELWMTLFGTTEWFGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKGDAKESYK"
     gene            complement(7630..10395)
                     /gene="mgtA"
                     /locus_tag="PC592_000577"
     CDS             complement(7630..10395)
                     /gene="mgtA"
                     /locus_tag="PC592_000577"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDF4054594.1"
                     /translation="MNKKENRMAVRQTVEKTVIRDEQNRRIQFAATNPIKEVLKKFHT
                     TPRGLEVDAIPVSRAKYGTNKVTHEKKKSLAKRLAGAFINPFTAILFCLAVVSTITDM
                     IFPYFSLFGSVPEDFDYLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNQEKKEIPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTSIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLEAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEATDSRLTDLSENYVKVDEIPFDFTRRR
                     LTTVVQDKGGKTQMVTKGAVEEMLSICAFAECNGEVQPLTDDIRYRILETVANLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECEMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVADSTDVFAKLTPDQKVRV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIILNLIYDLSC
                     TAIPWDNVDEEFIAKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFLQSRAS
                     APVTLLTMTGITVLTIIPFTVFGTMLGFVALPATYFAYLIPCILLYMILATSLKKAYI
                     RHFGELL"
     gene            complement(10560..10871)
                     /locus_tag="PC592_000578"
     CDS             complement(10560..10871)
                     /locus_tag="PC592_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF4054595.1"
                     /translation="MDFTCIFFGILFTFAGFWLAVGKGYRHLSLWKNMPKEEKDKINI
                     VPLSRNVGGIIALNGIIFLMKGVLPGFSNHWFIFSIIAWLIVASFDVWYIEKSVRYRN
                     Q"
     gene            complement(11255..11758)
                     /locus_tag="PC592_000579"
     CDS             complement(11255..11758)
                     /locus_tag="PC592_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF4054596.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDYAKDLLSGIQEMIR
                     GEVSSLLLGSSEESDCPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYLLDNSNIMAFIRKLRKKIEPAPDSPTYILTIWGIG
                     YKFNDQI"
     gene            complement(11774..14437)
                     /gene="mgtA"
                     /locus_tag="PC592_000580"
     CDS             complement(11774..14437)
                     /gene="mgtA"
                     /locus_tag="PC592_000580"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDF4054597.1"
                     /translation="MSKATLFDSRIKKYAYCEISEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFLASNFARNATTAIII
                     FSMILISGVIRLIQELRAKSAAAQLDRLVHESVTVRRGGKLIEIPGEELVVGDIVLFS
                     AGDCVPADVRLTKITDLFISQAAITGESAILEKSCRKLSYGEQETLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKDSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITGGKWMESFAFALSVAVGLVPEMLPMVITACLAKGSLAMSKKQTIIKNINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDILGNENAEVLDLAYLNSSYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNYVEYHGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGISTERILTS
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLKLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIGFTYLTFAGGASLFGLTKLPLW
                     YFVFLLLVVFLYMLMNSVAKYFYKKKYQELI"
     gene            complement(14536..14745)
                     /locus_tag="PC592_000581"
     CDS             complement(14536..14745)
                     /locus_tag="PC592_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054598.1"
                     /translation="MVKVKTKKTFVCTHMCKVEIPMSVRKLYEKVLASSIRAPNLEGM
                     IEKFDKDLPHSNDTDLIELKNAISK"
     gene            complement(15341..15571)
                     /locus_tag="PC592_000582"
                     /pseudo
     CDS             complement(15341..15571)
                     /locus_tag="PC592_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(15562..15762)
                     /locus_tag="PC592_000583"
     CDS             complement(15562..15762)
                     /locus_tag="PC592_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054599.1"
                     /translation="MNDGYISYTFNESYTKDEDETAYCTKVTDTLIELFKIDMETQKY
                     NPQGNASLEGAEFTWKSYVGYN"
     gene            16380..17717
                     /locus_tag="PC592_000584"
     CDS             16380..17717
                     /locus_tag="PC592_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4054600.1"
                     /translation="MESFIMLDMFITIVSSIIELWACKKVFDYTSKVKTSLINLYFLI
                     STFIIISTFYTNVGADNRILICIFVMFVFYKLNYDVNIYKCLIVLFSYWAILVCINAL
                     SMIVIVSINNLSSMNILLNDNFYRYETIVLGNIVLIVLLYIYKFISNDLQVTKREIYM
                     CIPIVANMISFFIFYKYILKLLDISSATKLDILIMVILLTFSNIALIYSLVKILKNNK
                     KYIELTKLQEKINAENKYYSNIKKYYIKTKELNHDMKNHLICIKEMNKKNIDTSNYIN
                     NIEKKLDEYSTVFDTGNITLNIILSEKKELCIEKEIDFTININFSDCNFIKEEDTCSI
                     FANALDNAIEACEKIKNDDKKIKLQGMIVNKFFVIKITNTKSNDILLKKNTFLTTKED
                     KEFHGLGIKSIKNSLEKYGGAISINFSENLFCLNMMIPIRKSQKDSNIAYENS"
     gene            17760..18347
                     /locus_tag="PC592_000585"
     CDS             17760..18347
                     /locus_tag="PC592_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF4054601.1"
                     /translation="MIKSCADKIAFLFVLNQVIEKDDLEICSYGLEILLSSIINTLSS
                     LMIGLILGRLIYSIVFLISFCIIRQFSGGYHANSNKNCILIFNSIFFISMVLGIILND
                     SNPIPLFLVILSSFNFLSIFIFAPVCHANNPLNETKYKKNKLMSRIISITLFLIILLG
                     CKYLSFYNYVVYTFLALLWINLLLIIQIIINKKII"
     gene            18360..18494
                     /locus_tag="PC592_000586"
     CDS             18360..18494
                     /locus_tag="PC592_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF4054602.1"
                     /translation="MKKILYHFMKACGVLAMFVAFLSANTTSLWHVYQPKTPEKLKKF
                     "
     gene            complement(18688..20253)
                     /locus_tag="PC592_000587"
                     /pseudo
     CDS             complement(18688..20253)
                     /locus_tag="PC592_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013280575.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            20701..21522
                     /locus_tag="PC592_000588"
                     /pseudo
     CDS             20701..21522
                     /locus_tag="PC592_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003520701.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(21547..22167)
                     /locus_tag="PC592_000589"
     CDS             complement(21547..22167)
                     /locus_tag="PC592_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4054603.1"
                     /translation="MSDNLVNDTNSTRLGGIDRYDTNKKIVNKFYNGAKEFYIASGTD
                     LVYALVGSTIAKNDPIILVDTNSDKNILEGSSKITAISIENSSIIQQCIDVSNGIKKY
                     GWIKLGDSWHYYNKDGTEVSNYDLALKKANKVLGDKYEAYLIENTDSLPNFAQTYLDE
                     CYFFGITYKIDDSDSAILVNKKNFYAFQIDSVGRISELEKYSDPSF"
     gene            complement(22416..23777)
                     /gene="rlmD"
                     /locus_tag="PC592_000590"
     CDS             complement(22416..23777)
                     /gene="rlmD"
                     /locus_tag="PC592_000590"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF4054604.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEEACKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMNEFKDMLLGIDLKSELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKRYGYEIRMVKCMDMFPNTPHCETIVKL
                     VRE"
     gene            complement(23804..24526)
                     /locus_tag="PC592_000591"
     CDS             complement(23804..24526)
                     /locus_tag="PC592_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF4054605.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYVSATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEIKLIEER"
     gene            complement(24526..24855)
                     /locus_tag="PC592_000592"
     CDS             complement(24526..24855)
                     /locus_tag="PC592_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HDF4054606.1"
                     /translation="MPQIKIRGINEDDICKISEKMIDDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEIAWFDRGQEVQDTVARIITDSIRTNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            25185..26111
                     /gene="fba"
                     /locus_tag="PC592_000593"
     CDS             25185..26111
                     /gene="fba"
                     /locus_tag="PC592_000593"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HDF4054607.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(26726..28357)
                     /locus_tag="PC592_000594"
     CDS             complement(26726..28357)
                     /locus_tag="PC592_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4054608.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     KNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNKNNVVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLKGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNIIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(28839..29876)
                     /locus_tag="PC592_000595"
     CDS             complement(28839..29876)
                     /locus_tag="PC592_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF4054609.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(29895..30680)
                     /locus_tag="PC592_000596"
     CDS             complement(29895..30680)
                     /locus_tag="PC592_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF4054610.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEYDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKIGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(30713..31846)
                     /locus_tag="PC592_000597"
     CDS             complement(30713..31846)
                     /locus_tag="PC592_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF4054611.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAAGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(31894..33021)
                     /gene="hadC"
                     /locus_tag="PC592_000598"
     CDS             complement(31894..33021)
                     /gene="hadC"
                     /locus_tag="PC592_000598"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HDF4054612.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTKLVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(33021..34247)
                     /gene="hadB"
                     /locus_tag="PC592_000599"
     CDS             complement(33021..34247)
                     /gene="hadB"
                     /locus_tag="PC592_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HDF4054613.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEMAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLIEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(34262..35062)
                     /gene="hadI"
                     /locus_tag="PC592_000600"
     CDS             complement(34262..35062)
                     /gene="hadI"
                     /locus_tag="PC592_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HDF4054614.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(35101..36300)
                     /gene="hadA"
                     /locus_tag="PC592_000601"
     CDS             complement(35101..36300)
                     /gene="hadA"
                     /locus_tag="PC592_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HDF4054615.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKGQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            36994..37992
                     /locus_tag="PC592_000602"
     CDS             36994..37992
                     /locus_tag="PC592_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF4054616.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENIVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLIKTEDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            38366..38893
                     /locus_tag="PC592_000603"
     CDS             38366..38893
                     /locus_tag="PC592_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HDF4054617.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASIVAGIIGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            38920..39516
                     /locus_tag="PC592_000604"
     CDS             38920..39516
                     /locus_tag="PC592_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HDF4054618.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAMFIKEKSSIKIRINTNG
                     LSDLIHNKKTAIMLKDVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPKEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(39581..41164)
                     /gene="asnB"
                     /locus_tag="PC592_000605"
     CDS             complement(39581..41164)
                     /gene="asnB"
                     /locus_tag="PC592_000605"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF4054619.1"
                     /translation="MINLEEKYSTRKDTCMIKILEYNGHIRNWKVLCEELGIDSSLGR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYKTEN
                     GKLLYSSSIRKLMEQPGFVKELNEEMLQMYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIERYWKPEFHPDYSKSIEEWTDEIHTTLQKIMPEIKSEDETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEEWFDESKLAQQTTDILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNVYHKAKCYGENLKTFYI
                     GNTNIMKEDEKRKILKKYNPDVLPIKLTKRIYEETEELDTLTNMSNIDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRMPSEYKVKGGENKIAFRKAASKVLPEEIA
                     FRNKLGFIVPIRIWMADDKYNQDIRDKFNSEIADKFFNIDEINEIFNDYISGNSNNWR
                     KIWTIYTFLVWYEIYFVKC"
     gene            complement(41731..42567)
                     /locus_tag="PC592_000606"
     CDS             complement(41731..42567)
                     /locus_tag="PC592_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4054620.1"
                     /translation="MNYIIKKVLNSSVVLVHDANDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDISVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSVDDLLFNQMKRSNPKEMSIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(42591..44057)
                     /locus_tag="PC592_000607"
     CDS             complement(42591..44057)
                     /locus_tag="PC592_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF4054621.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGSKGWSVSDVAKAHFDVDV
                     KDYKSNNEITTRDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDTEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEGVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLAAQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEQDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDVTSGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRIDYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(44060..45922)
                     /locus_tag="PC592_000608"
     CDS             complement(44060..45922)
                     /locus_tag="PC592_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4054622.1"
                     /translation="MDYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVDRAQFQVVIGNSVVDVYDEILKVCPLDTNDSAIKTEEKINLGTRFIE
                     FIINIFQPLVFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLIAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPSIAYNAQVFPAILCVS
                     FLSIMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAVLPFMVATGMHKALTPYAINTIGKLGYEALYMTASLAHNISESGVC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAILGVVLSSAISGIFLG
                     LFTVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNIE
                     QSSIENVVEEEPIEGKEVNILVSPVEGKVIDLSKVSDELFASKTLGEGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNSNGADYDYKVLNQSYGNVTKGSILFDVKGGI"
     gene            complement(46169..47032)
                     /locus_tag="PC592_000609"
     CDS             complement(46169..47032)
                     /locus_tag="PC592_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF4054623.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDKVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFVKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKVIWEIFNNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(47087..48019)
                     /locus_tag="PC592_000610"
     CDS             complement(47087..48019)
                     /locus_tag="PC592_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HDF4054624.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKYVISHDYEYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENSLDEFTTLTEATHWSGTTYGGES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEHLKTLLCVGGVHFEK
                     SFSDIIKNKEFNISIGHVLPNQWIVSGMYDDESGLEKLEKCINSIADGIDGIVFHDKL
                     KGTYKEQCRKLGEKLNIPVFKHKILKNPKDLPIW"
     gene            complement(48105..48656)
                     /locus_tag="PC592_000611"
     CDS             complement(48105..48656)
                     /locus_tag="PC592_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4054625.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDVDHFIEDDGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYVVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYV"
     gene            complement(48881..49372)
                     /locus_tag="PC592_000612"
     CDS             complement(48881..49372)
                     /locus_tag="PC592_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054626.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMNDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(49400..49960)
                     /locus_tag="PC592_000613"
     CDS             complement(49400..49960)
                     /locus_tag="PC592_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF4054627.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVNNWIDIEKIIKQGI"
     gene            complement(50112..51269)
                     /locus_tag="PC592_000614"
     CDS             complement(50112..51269)
                     /locus_tag="PC592_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF4054628.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVLIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDNILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASRNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKSRTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(51306..52247)
                     /locus_tag="PC592_000615"
     CDS             complement(51306..52247)
                     /locus_tag="PC592_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054629.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDKKKNEEISNNKNL
                     NNKQNKNIQNKESNEEGSNNIKEKNNSDSNVSVNNKSEKQEDTTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNTETNSIN"
     gene            complement(52334..53026)
                     /locus_tag="PC592_000616"
     CDS             complement(52334..53026)
                     /locus_tag="PC592_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF4054630.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYENMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(53135..53947)
                     /locus_tag="PC592_000617"
     CDS             complement(53135..53947)
                     /locus_tag="PC592_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDF4054631.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(53998..54909)
                     /locus_tag="PC592_000618"
     CDS             complement(53998..54909)
                     /locus_tag="PC592_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4054632.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYIFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVRIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIKAGKIELNNEIFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLHQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(54968..55699)
                     /locus_tag="PC592_000619"
     CDS             complement(54968..55699)
                     /locus_tag="PC592_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDF4054633.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFEKLNDVYKSLPVGNCLGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTKKNPCPFKDNNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMTLDSNIYSSGCIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEPEIRKRTIDRIKRIILV"
     gene            55788..56039
                     /locus_tag="PC592_000620"
     CDS             55788..56039
                     /locus_tag="PC592_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054634.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            56273..56692
                     /locus_tag="PC592_000621"
     CDS             56273..56692
                     /locus_tag="PC592_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054635.1"
                     /translation="MQIYFRVKAIGKRKPMLKLAPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIVNFLTNEEIESQANIGRVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSPINLKSGDIFTFIRLTLLAGRMF"
     gene            56717..61774
                     /locus_tag="PC592_000622"
     CDS             56717..61774
                     /locus_tag="PC592_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDF4054636.1"
                     /translation="MLERTRVEKNPKIIENLKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISSYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQEVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMISKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEVYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETSFDLSNTPIDKDFNARKEQFESLKHTLENLNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNREIVLTLLRKLELTDMELDKITNLLSLKTSSIRQTVIKILLEQDDSKLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTDRKELYKKLILLIKDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDNSPSLSKLDKIISNTSLSTNEDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLNLDYKLILDILFYSISTCGYNEIEKSWF
                     SSIYSNVLDSKKQNKISTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEVYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTKEQVNREMISGYNATNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPQSFMDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACAIAMENLA
                     RSAGFEDINRMMWALETEKLNEVAYIFKPKNIDRTSLWIDVDEKGKTSIKVQKGDKAL
                     KSVPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGEIYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQVQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PIIFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKVNNVNFEGSHA
                     LIEGTLGEYSVHMGSGIVHKKGIGALNILPVHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            62089..64656
                     /locus_tag="PC592_000623"
     CDS             62089..64656
                     /locus_tag="PC592_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF4054637.1"
                     /translation="MNLRFTRYIKSYKARSLAIAVSIILATSLVVGIGTLSRSAQQAD
                     VDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYTSTDVNEKLPINILYAN
                     KNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETFKVV
                     GILEDRFIEKQKGQCEIFSNLNESKLNDFTTYIEFNEGSDINTNIDNIIKNAMLDEKS
                     IGRNSMLIESTMKNGTLDNASKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLRAIG
                     STNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFVIPD
                     KIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTTVNYLISKLTLNM
                     SVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYMNAD
                     FILSNVYLNEIGSNTSFKDIKGFSDSQIDKIKNIDGIDKVKTASILNTRIEVNKINRL
                     DYYEAINSNPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINLKEM
                     KKENLAIVYVPEISKTQKYTKTFTPGEGTPAIDIKVGDTIKVKYPKGGMDTGLYESLK
                     DNYEYLEYEFRVGAIISYTFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYADLN
                     ENANKKKINNLLGKIGSEVSGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFIISVL
                     NIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGLIIQF
                     KMYYTQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINITE"
     gene            64668..65339
                     /locus_tag="PC592_000624"
     CDS             64668..65339
                     /locus_tag="PC592_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054638.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVAGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIEDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKVDKIISIIDGE
                     LKLTL"
     gene            65366..65707
                     /locus_tag="PC592_000625"
     CDS             65366..65707
                     /locus_tag="PC592_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054639.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(66060..68702)
                     /gene="adhE"
                     /locus_tag="PC592_000626"
                     /gene_synonym="adhC"
     CDS             complement(66060..68702)
                     /gene="adhE"
                     /locus_tag="PC592_000626"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF4054640.1"
                     /translation="MEKKENVVEKSSVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNAKIVGQPAHIIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTASSGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGNTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLEGLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        23405 a        11638 c         8701 g        25513 t
ORIGIN      
        1 aaaagatata caaactaata agttgtaatc tcttttaaac tctaaattaa aattatttta
       61 tacaatataa ttaaatatat tgcttataat aaaaaccata tttaaatttt agattggttg
      121 aaaattatta atattcattt ctcaactcag cttgcttctc ttcttttttc ttgttatctc
      181 ttgaatgtat tctttagtta caaggtttta cttttctcat atattataaa gaaaaatagt
      241 tttttacaaa taatccattt aatactatcc ttacttccaa cctaaatttc ctctattcca
      301 atttctttta agtattcata tacgccatta taaaaacttg gttgcattgt aatatcactt
      361 tcatcacctg tcggaacaaa tataacaaaa ccttgtcttg cccttgtaag aagaactcta
      421 tatgcatttt ttaagtatag tatattatcc tctttattga tattctgcca tttagttcca
      481 ttaaaattat agtattcaaa ttgctcattc ttaaatctta agtttccatc ccaacaaaca
      541 attgtccaat ctagctctaa gccctggata tcaaactctg tcgcagtttc ttctaaaaaa
      601 tatgaagctc gtacatcatc cttaccatta agaaaccagt ttttcgcatc aactttactt
      661 tgtacccaaa ccccatactt tcgaagtcgt ttagcgccag aacttgcagt cattccgtaa
      721 cgctgtgaac cttttgattt atctctcacc cactttttag ctaattccaa atccctagta
      781 acacatatag gataatcttt tttaaactga ttatataatt catttgcagc aattttatct
      841 acatctaaaa cggctttaac aaaggctgct actttttcac ttctaaaaga acgtaatgat
      901 acagataggt gcaaatcgtc aattattcta taattaacgc cttctgttaa ttcatcaaaa
      961 gaattacctt tagaatattc ttcatcaata attttatttg atatgtaaac atcccaatca
     1021 gaataattat ttcttagtga tgcaaaccaa cctgatattc catctgactc tcctttattt
     1081 atctcttggc ctccaccaat caaacaaaca atagtcgccc atcctatatg acgatttaaa
     1141 atactaatga gaaattcagg ctctgacata ttaaaatcta atacaccttt ttttcttttc
     1201 ataaagttag ttaaattagg ttcatcccat gcgcgttgtg cttcatcaaa aattgtgact
     1261 ctttcaatag gtggtgtatc aacagatata gcttcatctc taaaatgatg gattatctga
     1321 ataaattctt ttgcttttcg tatcgcttca gtttttcgtg ttccatttct ggttacatca
     1381 tcacgagcta atgcttcttg taaaacatca actaatggac catttccaga aaggaagact
     1441 gcatgttcat tttcatctac cttttgtcgc tcaatagcaa tattaaggcc agcaagcgtt
     1501 ttacctgctc caggaactcc tgtgataaaa catattgatt ttttattatg aatcttacta
     1561 tagtctataa ttttatttat agctttagtt gtttggttta aatttttagc acttgcatca
     1621 tttcttgaaa tatcttcaac attatggccc atatataaag cttgtgcagc ttcaataatt
     1681 gttggagttg gcatgtataa tgagtccatc caagcatctg gattaaatga acttttgtta
     1741 tatgtagtac aaacctcctc tatatacttt cctatattaa actcattact acaataagtt
     1801 tctaaaatat tttccttcat caatcttatt ctttgatttc tttgaggagc ttttgtacaa
     1861 ataagtattg gtactaaaag tttatcatga ctttccttgt gaaaacaatt aaggtcaagg
     1921 gcatagtctg taacttgttc aattgcatac ctaggataag tatcttcatc aactttaaat
     1981 tcaaggagaa aaacaatgcc tttgtaaatt aacacattgt caattctact gcctattcgt
     2041 ggtattgtat actcaaataa taagtgtcca tctttgaaag ttgagagctc tctttttaat
     2101 atttcaattt cctttttcca tgtattcttt tgcaggtcat tagcctcaaa ttgatcatta
     2161 catgttatct caccaaatat agtaaaaata tctttaccta taaattcatt tacgctactt
     2221 gaataatatg ctcttttcat acatcctcct cctttatatc taattaacct tatagtctac
     2281 atctatccta cagtctaaac tataacccct atgatatcaa tcctgtagtc taaaatctga
     2341 ctcctatact ctataaatac actgaataga tatgtttatg tatggtactt tgataataat
     2401 ttttctttgc taagtaaatt atcaaatttt caacaactat ggatatttct gaaaaatgga
     2461 ctcagaaaat tagaaattgg actcaaattt tagctcattt aagtatttat tttgaataaa
     2521 aaaatttaac tctaagttaa taaacaagca tttcaaaaaa tcaaaaagtt ttctgaaagt
     2581 gataataatt ttgcaaaaat agaaaaattc aaaaaaggct ataattttta aagtcatagc
     2641 tttaccaata aatgtttact tgtcacttaa aaaataaagt tttgtttaaa gaatacatat
     2701 aaacatttcc agactcagat ttatttaaaa tttatttact aagaagtttg atactttctc
     2761 catcaccttt tgtacaataa gttatgtgat atcttataac actcatctca agtcaataaa
     2821 ataataataa attttattat atactagcaa gacttatcaa acaaaaagaa aaaacatata
     2881 gactatttag ttaatatgtt tttccatata ttcttattat attataaaat ggatagcgca
     2941 tcatttaaat cattgattaa atcttcacta ttttcaagac ctaaacttat tctaattgtg
     3001 tatggtgaca catttaacgc tttggcttgt tctaaagtca tttcatttaa tatagctata
     3061 tttggagcaa acactaaact ttcatgacct ccccaactca ctcctatttt aaataaatct
     3121 aatttattta caaatttttt aatatcattt acatcctttg cgtctatttc aaaacttaat
     3181 aacgcagtat agttaagcaa ctgtttcttt gctagttctt tttgagtaaa atatttagat
     3241 aaaagtacat atattctcca agattataat tagtatatag tgtagtcatt aaaaagttca
     3301 ttattgtatt atcattttcc aacaaagata taatataatc aaaaaactct ggtttattat
     3361 aaaattaatt atgatgtctt cttcgttact agcttctatt tcatgaataa catgctgatt
     3421 taaaaatatt aattctcctt gttttaaatt aattttatat tcatctatag tttgtaccaa
     3481 ttttcctcta taaacataat taaattctat ataattatgt ttatgttttg gaaattgtgt
     3541 aaatcttgta tgttttctta tatgtatcaa ctcatctata ttcaataact tgttgctatc
     3601 tattataaat tgagaattat cagtataaat acttttatct attatataat ttccttctag
     3661 tatatttttt tcttcttctg ttatttccct caacttatca tgaatatatt gtctcatgag
     3721 atacctcctt taataaaatc cttgatttta tacgatattt ttttggagtc agactatatg
     3781 tctctttaaa ttttttatag aagaaggttt ggttattata tcccacttca atagaaatgt
     3841 cttctatact catatctgta ctttttaata atgtagttgc ttttttaagt ctttgttcgt
     3901 ggatgatatc cttgaatgat ttacctgttg tcttttttat taaagtactt aaataatttg
     3961 gatgaaaatg aaatttttta gcaacctccc ttaaagttgt ttgtgcataa tttccctcta
     4021 tatatttcat catttctgca atattatcta tattaatttt actatcagat gttaaagttt
     4081 tttcattttt agttttatgt atctctaaca attcataaaa tattaatata atgtaacaat
     4141 ccattatttc cttataacac attgatttat tcaaatattc cttagttagt tcagctacta
     4201 gtcgtttcaa tttaaaatta tttttagcat taaatatata ataattatca catctttttc
     4261 ctttgtgtat agctcctgct aaaaaattat atattaactc attagacgaa actctagaaa
     4321 aaaagatgca tcaaaatatt ctctcctcat tatacaatta ataatgatgt cattttcttt
     4381 tactgcattt attgaatgtt ctacattcat atccaagaga catatttcac cttcttttaa
     4441 tatggtttct tttccatcta taatttgagt acatgaacca ctataaacat aaattaattc
     4501 tataaagtta tgtttatgtt tgggtatatc tataaatcta tgatgtttgg ataccataat
     4561 gtcttcatct aaagaaagta tatttttatc tgttagtact atagttccat ttacttcttc
     4621 ccaacataaa atagtatgca atatagacat tattttttta ttatctaact tttttacatt
     4681 attagtatct atacattcta atatgtacct ttctgcttgt gttttttgtt taagtatatc
     4741 ttctagcgtt ttatctttca tttatatccc tccagaatta gctatacttt attacagttt
     4801 taaattagat taagaatatt ctttatttaa ttgtatcata ttaatttttg acagtaataa
     4861 tgttaaatta tgacatttaa aaataccttt ttttgtttta aaataaattt ataagtaaac
     4921 atttaaaatt taggaggtat ttttttatga atacagtaca taaatgtttc aagatgaagc
     4981 tttttaaagg atttgaaaat gaatacaaga aacgtcatga tgaattatgg tctgagatga
     5041 tagatatgat tcatgaatat ggtggtagta actattctat ttttctagat gaagaaacca
     5101 attatttata tggatatata gaacttaaag atgcaaaact atgggataaa agttcagaga
     5161 cagcaatctg caaaaaatgg tggaattata tgtctgatat aatggaaacc aatgaggata
     5221 atagtcctat atctatagaa cttaaatcta tgttttattt aaaataaaga caagaattat
     5281 tataaattat aaaaatgggg atgtatcaaa ataaaaactt gagttatctc cttttttata
     5341 taaaaagaga agtgattcct aaaaacctct aacctatatt ataattgttc tgtgaaaaac
     5401 taaaaataca tttcgattat agtagctaca aatgctataa acaagtggta tttctactag
     5461 acattgaaac aattattctc aaagataatt cagtaagact atttaaccta actttagagt
     5521 aattgatata tcttatgttg ctgtttatat taattaaagt atataattta tactatgatt
     5581 actattttct ttcaaactta gaatatgttc ttgctaattt ttttatttct cttgcgttgc
     5641 attctttgtg ttcccttata tatgttaaaa ctgaataata taattatgta ttatctacat
     5701 ttttatttac tttttttctt atctagcata ttcaagatat tgaataaact gttttaagca
     5761 aatttaaata gtaggtatta gataaatatt ttgtttgaca atttgaataa gtgactagta
     5821 ttcctataat tagtattata cagtattaat cataggaata tttatgttaa ggtgatttaa
     5881 ttttcaataa gtatatataa agagtactct ataaatgaat tttacaaaga aatttaatta
     5941 agtaaatcta tactaacaaa tatgttagat agattagaag ttcaggggaa tatataaaaa
     6001 cttgtgtgat tgtaataaaa gaattacact catattaaac actataaaag tagataatgt
     6061 tattaaaata actgaaaatg caataaataa aatagataca atattttata gtaattttga
     6121 aattgaagac atgaaaaagt tgaaaaatat ttagagcaaa tatttcctaa tctcaaaaat
     6181 atatattaaa taggagtgtt gaaaatgtct aaaataatag catttgtagg aagcccaaga
     6241 aaaaatggta atgtagatac aataattaat gaaataatta aaggagcaaa taaaaacaag
     6301 gttgatgtaa aaaagtatta cttaaatgat atgaatataa aaggttgtca gggatgttta
     6361 tattgtagaa aaaatcattc atgttcactc aaagatgata tgattcaagt atatgaagat
     6421 ataaaaaaag ctgagtatgt aattataggt tcaccagttt atatatgtca ggtatcagct
     6481 caaaccaaat tattattaga tagactttat ccacttacaa caatagataa aggtaaacat
     6541 atacctagat tcggaaataa aagaataatt atggtttata ctcaagcagc acctttacca
     6601 atattcttta aaagatattt tagatataca agtaagcatc tcaaaggaat gggtttaaat
     6661 cattataaaa ctataattgc tactaaagca tttgaaaaaa actcaattga aaataaccct
     6721 aaaatattaa aaaaagctta taaccttgga tttaaaatat caaaggatat taatgtataa
     6781 agtctacttt agatatttcc agactcgata tttcctgaaa gatggtgaac attataataa
     6841 ttcaccatct tttttataat tctatttgta aatattctac ttaaaaagta ttatatatat
     6901 aaaattagat gacaatatta tttgataata gagtatattt tttaaaatct ataaatattt
     6961 cattatatta ttttttataa taaacattat tctataaaag tgacgtacta ttttctcctg
     7021 aatatctgta gttgttttta catcacattc ctcaataaat ttttttaata tttcgttttt
     7081 attaaagata aaaaatgtgc atcttccttt gtatagtgat atttgatatt ttgattatca
     7141 caacttttta gaagaataca cactttattt taaatacact gctactatgt tattagaaaa
     7201 tggtgctagt ataaaagata tccaacatat actacatcac actaaaattt caacaactat
     7261 ggatacatat tcacatataa ctaattttat tcttctttca cagatttcct cattttatcg
     7321 aaacttcttg tacagacata cattccataa taaaatctac cttttaatat tatttcacga
     7381 tttcgttata gacgcgtaaa caaacaataa aaaactgtgc atctcccttg cttcattcat
     7441 actgacattt tatttataag actcttttgc gtctcctttt ggtttcatgg accaaaacac
     7501 tacattcatt acaatgacaa tcagtaatac aactgccata gccacccaaa agccgatatt
     7561 aagaccaaac cattcggtag ttccgaaaag ggtcatccaa agttctttcc agttcatcat
     7621 tgcacctcct taaagtagtt cgccgaaatg acggatatag gcttttttca aacttgttgc
     7681 caaaatcata tacagcagaa tacatggaat cagatatgca aagtatgttg caggcaatgc
     7741 aacaaatcca agcatagttc caaacacagt aaacggaata attgtcagaa ccgtaattcc
     7801 tgtcattgtt agcaaagtca ccggagctga tgcacgactc tgaaggaaag gcagctttgg
     7861 agtacgaatc atgtgaatga ccaatgtctg gctccacata gattccacga accatccagc
     7921 ttgaaacatt ccgatatact gcgcctgaag cattgccagc tctgcaccgc tgaaatgggc
     7981 aggcaaatca ttgaataaca caccattcga tacgaacaat gggcaaaata caaagtacat
     8041 aaaaatatat gttgtaaaat cgaagataga gctagttggt ccaatccaga tcataaaact
     8101 tccaacactg gaagcgtccc atttacgtgg tttggcaata aattcctcat ccacattatc
     8161 ccaaggaatt gcggtacagg ataaatcata aattaagttt agaattataa gatgaacact
     8221 catcattggt aggaagggta acagagcaga tgcagcaagc actgaaaaca tattgccgaa
     8281 gttggatgaa gcagtcattt taatgtattt aatcatgttc gcatatgtct ttcgtccttc
     8341 aatgataccc tgttccaaaa ccatcaggtc tttttccaat agaataatgt cagcagattc
     8401 ttttgccaca tccacagcgg tatctaccga aataccaata tcggcagctt tcatagcagc
     8461 agcatcatta ataccgtcac ccatgaaacc gaccgtatga ccattttcac ggagaacaga
     8521 aaccacacga actttctgat cgggggttaa cttcgcaaat acatctgtag aatctgccac
     8581 tcttgcaagc tctgcatcgc ccatttgttc caaatctgaa ccgagaagca tattgcgaac
     8641 ctctagtcct acctgcttgc agatagttcg agtcactttg tcgttgtcac ctgtcaaaat
     8701 tttggtgata acaccatggt ctttcagagc tttaatagca tctgcagtag attcttttgg
     8761 aggatcaagg aatgccagat atccaatcag taccatctca cactcatctt taacaccaaa
     8821 tgcgccgatt ggggaaggat tactcttctg tgcaatcgct agcactcgga atcccttatc
     8881 gttaagattg gccactgtct ccaaaattct gtaacgaatg tcatcagtca gaggctgcac
     8941 ttctccatta cactctgcaa acgcacaaat agagagcatt tcttccacag caccttttgt
     9001 taccatctgg gtcttaccac ctttatcttg taccactgta gtcagacgac ggcgtgtaaa
     9061 gtcaaaagga atctcatcta ctttcacata gttttcggac aggtctgtga gacgagaatc
     9121 tgtggcttcc tcttcctcag ttttatggat aattgccaaa tccatcaggt ttttatagcc
     9181 agtctggaag taactattga ggtaagcgtg acgcagtact cgcgtatcgt cctcgccatt
     9241 tacattcaga tggtattcca gcacaacctt atcctgagtc agcgtgccag tcttatcagt
     9301 acaaagaata tcaatagcac cgaagttctg aatggaattg agatttttaa cgattgtctg
     9361 cttcttgctc atggaaacag cgcctttcgc aagacaggtt gttacaatca taggcagcat
     9421 ttccggtgtc aaaccaacag caatagaaac tccgaataag aaagcctcca accaatcacc
     9481 cttggtgata ccattgacaa agaacaccag tggaaccata atgagcataa aacggatcaa
     9541 tacccaagaa acggcgttta cacccttggt aaagcttgtt tcaaccgcct ctccggcaac
     9601 tgcggacgcc atagagccaa acagagtatg atcgccaaca caaacaacaa cagctgttgc
     9661 gctaccagaa attacattac tccccataaa agcaatgctt gtgtaatcag tcacgctttc
     9721 tttctgagca cttacattgg gggttttttc gataggttca ctctcaccag taagacttgc
     9781 ttgactgaca aacaaatcct tcgcatccaa aatacgaaca tccgccggaa tcatatctcc
     9841 agcagacaga tgtacaatat ctcccaccac caaatcatcc ataggaattt cttttttttc
     9901 ttgattccta cgagtaactg tacaagtggt cgtaatcata gctaacaatt tctctgctgc
     9961 atttccactt ctggattcct gtacaaaacg aagtgtaccg gaaatgaata ccattgttaa
    10021 aatgattaca acagtcaggt aatcaaagtc ctctggcaca ctgccaaaca gggaaaaata
    10081 cggaaaaatc atatccgtaa ttgtggatac tacagccaga caaaataaaa tggcggtaaa
    10141 tggattgata aatgcaccag ctagccgttt tgctagagat ttcttttttt catgagtgac
    10201 tttattggta ccatatttag cacgacttac gggtattgca tctacttcca atccacgagg
    10261 tgtggtatga aattttttta aaacttcttt aataggattg gttgccgcaa attgaatgcg
    10321 gcggttctgt tcgtcacgga tgactgtttt ttctacagtc tgacgaacag ccatacgatt
    10381 ttcttttttg ttcattgttc ttacctcctt gaattttcat aggagcaagg aatattatat
    10441 gagtgacacg gaatctccaa attctcatct aatattctct gcatttgtgg actgacatca
    10501 gagtccatgt ctttcacctc acaatcttaa aaaatatcta tgtgaaaccg caatgcggat
    10561 tattggttac gatagcggac acttttttcg atataccaga catcaaagct ggcaacaatc
    10621 aaccatgcga ttattgaaaa tataaaccag tggtttgaaa atcctggcaa aactcctttc
    10681 attaagaata taattccatt taatgcaatt attcctccaa cattacgaga aagcgggaca
    10741 atattaattt tatctttctc ttccttcggc atatttttcc acagggaaag atgacgatat
    10801 ccttttccca cggctaacca aaagcctgca aaagtaaata aaattccaaa aaagatacat
    10861 gtaaaatcca tcgcttgttc ctcctttcaa tgcttaaacc tgtttcttag tttcgtcagc
    10921 ttcataagtt taatgaggag cacaatcata gtaacagcaa gaataaacca gatcataaca
    10981 ctcacctgat accatatctt aaagattgcc attctttgtt cagataaatt ccaacccaaa
    11041 tagctacata gtattgtaaa tacagggtag aaataaaaaa gaattgcctg tttcaaatct
    11101 ttgatttctc tcctcactca caacacctcc ctttaactac taacaatata taaaaaatcc
    11161 aagtagaatc atatggctaa agtcttgcga ttttcttgcg atttggtaag aaaatagacg
    11221 gactgaaacc gaaaatggtt ttagtccgtc tttgtcatat ctgatcatta aatttatatc
    11281 caatacccca gatagtcaaa atgtatgtgg gagaatctgg ggcaggttca attttttttc
    11341 gcaacttccg gataaaagcc ataatgttgc tgttatccag aagataatct tcctcccata
    11401 cggcacgata aatctgttcc tttgtaaaaa cttcaccttt gttctggaca agaaagtaca
    11461 aaatatcaaa ttcttttgga gtcaagttga cttcagaacc ttttatcagt acttttctgc
    11521 ctcttggata aatttcaaga tcccctgcta ggattctgtc tgacagagta cccactggac
    11581 aatcgctttc ttctgatgac cctaacaata acgaagatac ctctccgcga atcatctcct
    11641 gaatgccaga aagtaaatcc ttcgcataat cactgtctgg tggatctctt aatagttttt
    11701 ctaatagcca gatttcaaga gccgaatcca tcggaatata actaatattc tttttcatca
    11761 tgaatgcctc ctcttaaatc aactcttgat attttttctt ataaaaatat ttagctactg
    11821 aattcatcag catatagaga aataccacca gcagtaaaaa tacgaaatac caaaggggca
    11881 atttcgtcag tccaaacagc gatgcaccac cagcaaaagt aagataagta aagccaataa
    11941 tccctactag agttatagaa atgactggtg cagatgccct gctctggaaa aaaggaatct
    12001 tggaagttcg cagaaaatgt aaaatcaaaa cctgtgtcca catagattcc aaaaaccatc
    12061 cagtctgaaa cagagctaca tactgaagtt tcagagaagg atctgtaagc tgcagatagg
    12121 ttgcccctcc acatagcatc ggacatagga aataatacaa aaacaggaag gtaacaatat
    12181 caaacagaga actgattggt ccgaaagata gcataaactg tcttagtgtt ttgccagacc
    12241 agtctcttgg agatagcatt tcttcctcat ctacattgtc ccagggaagc acaatacaca
    12301 acgtatcata cagcaaattc aaaagcagaa tctgaattga agtcataggt aggaacggta
    12361 aaaaggcact ggcacaaatg atggaaaaaa tatttccaaa gttagagcta gcagtgattt
    12421 taatatattt cagcatattg gtaaaagttt ttcgcccctc cattacacct tgctctaaaa
    12481 cattcaagtc cttttgcaac aaaaccacat cagcagcatc ttttgctgca tccactgctg
    12541 tatccacaga gattcccaca tttgcttcat ttagtgctgg aatgtcgttg actccatctc
    12601 caagaaatcc cacggaatga ccattatcct gcatagcaga gaccagacgc accttatgtc
    12661 ccggagtaag ctctgcaaaa acatgagtat gttccacagc ctttttaagt tcacagtctg
    12721 tcatttcgtc cagttgtgta ctagttaaga tacgctctgt agaaataccc acccgacggc
    12781 aaacagatac agcaatcgct gcttggtccc ctgtcagaat cttaggaatc acttttaatc
    12841 ttttgagtgc agttacagac tcctttgctg tctgctttgg tgcatcaaag aaggatagat
    12901 acccaactag agtcatgccc cattcatcat caggagtaat tttcttttgt gctcctacat
    12961 tttttcgtgc caccgcaata accttcattc catcctgtaa catttcacct actacagaag
    13021 atacactctg tctcgcatcc tgccccatgg ggagaagttt tccatgatat tccacataat
    13081 tgcagcgtga aaagatatgt tcgatatccc ctttcataat aagctgacta ttcccattgc
    13141 tatcctgtac aagtgtgctg acaaacttac gagcatagtc aaatggaatt tcatcagctt
    13201 tttgaaattt tgtcagaaga tttgcataat gggcttcccg ccctggcatg gtattgcagg
    13261 caagaatggc attatcaatg gtattgcaga caccagaatg ataggagcta ttcagataag
    13321 caagatcaag aacctctgca ttttcatttc ccaagatatc catataatat tccagcagga
    13381 tactttcatt ggtaagagtc cccgttttat ccatacaaag cacatccatg ctgccaaagc
    13441 tctgcatagc attaatattt ttgataatag tctgcttttt gctcatagca agacttcctt
    13501 tggcgagaca ggctgtaata accataggaa gcatttctgg caccagacct acagcaactg
    13561 acaaggcaaa agcaaaggat tccatccatt ttccaccagt gattcccagt aatataaata
    13621 caatgggaac taatatcgcc atgaaacgaa tcatcaccca ggcgatagaa tcagctcctt
    13681 ttttaaatga atctttatca tcagaatccg gtttggtaaa tcctccatac agggtatctt
    13741 tacctactgc caacacaatt ccttcccctt ttccactgat gactgtggtt gccataaaag
    13801 cgaggttttc aagctgagtc agcgtctcct gttctccgta actgagtttg cgacagctct
    13861 tttcaaggat agcactctca ccagtgattg cagcctgaga gataaagaga tctgtaatct
    13921 ttgtcaatct gacatctgcc ggaacacaat cacctgcgga gaatagtaca atatccccta
    13981 ccactaattc ttcgccagga atctctatta actttccacc gcgcctcact gtgacgcttt
    14041 catgaactag gcgatcaagt tgagcagcag cgctctttgc tcgtagctcc tgaatcagac
    14101 gaattacgcc actaattagt atcatggaaa agataataat ggcagtagta gcatttctcg
    14161 caaaattgga tgctaagaaa acatctgtaa caagagaaac aatgcccaga acaaaaagaa
    14221 tcacatgaaa tgggttaata aatgctcgtc tcaatcgttg catcgtcgta tcattttttc
    14281 gcccattgaa gctgttcgct ccatatttct cccgcattga accaatttgc tcaatagata
    14341 gaccatctgg agatgagcca atgtctcgat agatttctga tatttcacag taagcgtatt
    14401 ttttaatacg actatcaaat agtgttgctt ttgacacgaa acatcccctc ctttataaat
    14461 ataaataaag atatccacat tataacacag tgttctaaaa atgctatatt tatattcttg
    14521 cttttttctt gcgatttact tcgatatggc atttttcagc tcgatcaaat ccgtatcgtt
    14581 agagtgaggt aaatccttat caaatttttc aatcattcct tctaaatttg gagcacggat
    14641 ggatgaagca agcactttct catagagctt tcgcacagac ataggtattt ccactttaca
    14701 catatgagtg cagacaaacg tcttcttggt tttcaccttg accatgtatc aaatttaaat
    14761 taactactta gagaagtttc tcatagtgat atatgtatta tgagtgatag aatggcaaaa
    14821 gtggcagtat agaaaacgag tgtaaaagca atacaattag tttgtatgga atatctgaac
    14881 tacataatta accactctgt agtttataaa acaatacaat gcgtaaattg gaacggaaca
    14941 gaaaaaacca atagtatttt taataattcc acttcactat tgattactct tatctattat
    15001 tgctatttac aacaaaataa aacaacagaa attttaaata tgttgactgg cataattcat
    15061 atgtatagaa agtctacagt taagatgcga tttttctaat ccaaatatat taagaaagga
    15121 attttacgaa gccattagta ctttgtttaa gatgtctttc ataaatataa agaataatgt
    15181 tcttaacaaa ggcgtgtaaa tttatataga aatgcatact ttaaataatt atcccacaat
    15241 atttcagtta ctgtctttat gtcccacaag ttcaaactac gacacctaca ttgcctttgt
    15301 ttgattgtca atgaatttca cagcacctta actttcacat tgtacccaac ttctcgatac
    15361 tccatacaat ctcatctgta actgtgtagc tggtcggtat atccgttcta atggtggtat
    15421 ctacattcaa gtcctgcaat tcctttgtca gataaccgct gattgtctac atccttactt
    15481 cgatagcttc tttgctacta ttccaagtgt agtagaactt tacaaagttt ttgacgaagt
    15541 ttttaatccc gttggtatca ttcagttgta gcctacataa gatttccatg taaactctgc
    15601 tccctctaaa gaagcgtttc cttgtgggtt gtatttctgt gtttccatgt caatcttgaa
    15661 aagttcaatc aaagtatctg ttacttttgt acaatacgct gtttcgtcct catctttcgt
    15721 gtagctctca ttgaatgtat aactgatata accgtcattc attacttttt caacaatccc
    15781 gatacgccct gtcgattctg tccaatacta tttatcagac gcatgaacca ctggtaatga
    15841 cagtagcaaa ggcaagaacg cccatacaca atcgctttaa tatttttttc ataattctaa
    15901 atactcattt cattttgtaa ttgggtaaaa aaatagacac ttattttgaa gtgaacatct
    15961 tgctttattt tagtactttt ctcttaaaac gcaatattct tcattatcta ttattatttt
    16021 atagcgagat tgatttaata atcattgatg aagtagataa tattgtttgg agaaatgaaa
    16081 gaagcactcc tatagaaaga gtacttttag tgtatattca agaatttctc taacatgatt
    16141 ataacatgtc ttatgtttta gtatgataat tttcgttcgt ttcgttcgtt ttattattac
    16201 aatgcatatt atagttttac tcatttatat taataattac atatgtagat aaaattattt
    16261 atatatatat aatatttagc aacttcatcc aagtataatc tattttatga tataattatt
    16321 ataaaagttc aaatcatttt cgtgttatta aaggaaattt atgcaaaatt gtttaagtta
    16381 tggagagttt tattatgtta gatatgttta taacaatcgt ttcttctatt atagaactat
    16441 gggcatgcaa gaaagtgttt gattacacaa gtaaagtaaa aactagttta ataaatttat
    16501 attttttaat ttccactttt attattattt ctactttcta tactaatgtt ggtgctgata
    16561 atagaatatt aatatgcatt tttgtaatgt ttgtttttta taaattaaat tatgatgtta
    16621 atatatacaa atgtttgata gttttgtttt cttattgggc aatactggtg tgcataaatg
    16681 cattaagtat gatagtaata gtttcgataa ataacttgag ttctatgaat attttattaa
    16741 atgataattt ttatagatac gaaactatag ttttaggaaa tatagttcta attgttttgt
    16801 tatacattta taaattcata tctaatgatt tgcaagtgac taaaagagaa atttatatgt
    16861 gtataccaat agtagcaaat atgatatcat tttttatatt ttataaatat atcttaaaac
    16921 ttctagatat ttcttccgct actaaattag atatcttaat tatggtgata ttattaacat
    16981 tttctaacat agcattgatt tatagcctag ttaagatatt aaaaaataat aaaaaatata
    17041 ttgaattaac taaactacag gaaaaaataa atgctgaaaa taaatattat agtaatataa
    17101 aaaaatatta tattaagaca aaagaattaa accatgatat gaaaaatcat cttatttgca
    17161 ttaaggaaat gaataaaaag aatattgata ccagtaatta cataaataac atagaaaaaa
    17221 agcttgatga atatagtact gtatttgata caggaaatat tactttaaac attatattat
    17281 cagaaaaaaa agaactttgt atagaaaaag aaattgattt tacaattaat ataaacttta
    17341 gtgattgtaa ttttattaag gaagaagata catgttctat atttgcaaat gcattagata
    17401 atgcaatcga agcttgcgaa aaaatcaaaa atgatgataa aaaaatcaaa ttgcagggaa
    17461 tgatagtaaa taaatttttt gtaataaaaa ttactaatac aaaatcaaat gatattttat
    17521 taaaaaagaa tactttttta actacaaaag aagataaaga atttcatgga ttaggaataa
    17581 aaagtataaa aaattcttta gaaaaatatg gtggtgcaat ttctataaat ttctctgaaa
    17641 atttattttg tttaaatatg atgataccaa ttagaaaatc acaaaaagat tcaaatattg
    17701 catatgagaa tagttaatat ccataattta ccaataaaat tatttaagga gaaaactaaa
    17761 tgataaaatc ttgtgctgat aaaatagctt ttttgtttgt tttaaatcaa gtaatagaaa
    17821 aagatgattt agaaatctgt tcatatgggt tagaaatttt actatcttcc ataataaaca
    17881 ctctatcttc attaatgata ggtttaatat taggtagatt gatttattct atagtgttct
    17941 taatatcttt ttgtataata agacaatttt caggtggata tcatgcaaat agcaataaaa
    18001 actgtattct aattttcaat agtatttttt ttatatctat ggttttggga ataattttaa
    18061 atgattctaa tcctattccg ttatttttag tgatattgtc tagttttaac tttctaagca
    18121 tttttatttt tgctccagta tgtcatgcta acaatccact aaatgaaaca aaatataaaa
    18181 aaaataagtt aatgtcaaga attatatcta taactttatt cttgattatt cttctaggat
    18241 gcaaatactt atctttttac aattatgttg tatacacttt tttagcttta ctttggataa
    18301 atttattact aattattcaa atcattataa ataaaaaaat aatataagga gatattaaca
    18361 tgaaaaaaat tctatatcat tttatgaaag catgtggtgt attagctatg tttgtagcat
    18421 ttttatctgc aaacacaact tctctgtggc atgtatatca accaaaaaca ccagaaaaac
    18481 taaaaaaatt ctaaaaatca ccaaaaagaa ggggctgtcg cataagcaaa ttaaatttgt
    18541 tctgtgacag ctcttttttt acttatttta ataggtatat ttttaattgt tttatattaa
    18601 gtttatattc taagtaaaat tatgcataac aaataaaggt ataaaaatac cattttttta
    18661 gataatattt aattataaac aataaattta gaatattttt tttaaatgat gaagatatat
    18721 tccatgttta ttttttacca ttttattgtg tagtctagaa atattatgag ctatcgctac
    18781 aataatacat tctgatagaa cattttcttt acctcagctt aaaaatcttc taaatttcat
    18841 atttttttta cttgagcgaa agctccttct gcttatatac ttctattcat tctaggttca
    18901 aacccttccg ggcttataat tctctttaag ttttcttttc ttttttcata aaataactta
    18961 gatacttgta agtttttagt cctattttca agaggaatct tactattact tctcttaata
    19021 caactgcttt tatattgaca ataacagcat tcttcacaag tataacaatt tatttcactt
    19081 ttatatcctg tttttgattt tctattgatt attttattag caaaagtttt tgccattttt
    19141 acaaatataa taatcatttt tttcatcata atccatatta tcaatacgcc caatctcatt
    19201 tttatatttt ctagttttac taatttcata atttgcaggc tttatgaaag acaattgatt
    19261 attacgctct aaaaatgtat agttttcctc accttcatag ccagaatcag ctactatttt
    19321 aggatattta aactttatat ggtcttcaat agattttaaa aatgatatta atgttgtagt
    19381 atcagtaggt tgatgccctg aacttaccaa aactatgtat tctgaatcta caccaaattg
    19441 tatgttatat gctgatttca attggccatt tttcatatgg tcttctttca ttctcataaa
    19501 agttgcgtca ttatctgttt tagaataact atttcgttca cccattatat gaaggtcttt
    19561 agtatatttt ttcaatctat caatataatt atttaattgc tctatagatt tttgaatgat
    19621 agattttttc tttccttttt catgaacaaa tactatattt aattcttttg atatttttct
    19681 tagtttcttt aaaagttttt ttagatgata gattttgatt ttatctttat agattatttt
    19741 aataccaaaa tcaatctcac atttcaatat gaagtcagat ctattagcag attactctat
    19801 ttttgtacca tcaataagca gagtatcctt tgaaatctcc ttattatatc caataaagtt
    19861 tgtaaactgt gcaatcaaat ttttgcttac ttgtgaaaaa taaatactac gaaatcttgc
    19921 aattgttgaa tggtctgggg cggaggctcc gcctagaaga tacataaagt taatatctct
    19981 tttgcatgct ttttctattt ctcttgaaga ataaatgcag ttcatgtttg catatattat
    20041 aattttcaaa agttgtctag gggttacttt atttcctcta attcgagaat aagtcttata
    20101 taatttttct aaattcatct cctcaataat ttgacttaat aaccttacag aatcatcttt
    20161 tggaatcatg taatcaatat ttagtggtaa tttaaattga taattatcac cataagtagt
    20221 ataatcaatt tgtatagtat tttgtttttg catacaatta ttatacaaga atcccaagct
    20281 cttttgaact tgggattttt ttatacaaaa aaatggcgta gcactatttt ctagtgcgac
    20341 agccccaact ctatattatt tagaaattat tactgtaatt ttactatttg aacatgtaca
    20401 ttcaaaatac aagtctagaa attagcttta tttgtaagat aaataaaatc agtcccatta
    20461 tcttctgtat gcaaactaat taagttattc ttttttaaat atttaattgc atatttttcc
    20521 tatatacata gcatttataa agaaagtttt atatacttaa actattatct tatttaaaga
    20581 tattaacaat aaaaacctaa aacaagaatt gtaatacaag ataaaatatt tgtctaaata
    20641 atattgctta tcactaagac aaaaactaaa ttaatataaa aatagaggtg attagatata
    20701 atgaataatt ataattctat aaataactta caaattggaa aaacatattc taatgacgaa
    20761 ataaaagaaa tatttaaatg ttctactcaa ggtggtatga taaaatcaaa tactacaaag
    20821 actctagtta tattctctga tcatacaaaa agtatatatg atgatatttg gtatgataat
    20881 acgttaatat acactggtat gagaaagaag ggtgatcagg tattaaaagg taatcaaaat
    20941 ataacacttt atgagagcga aactaatgga ataaaagttc atttatttga gacttttgtc
    21001 tcaactaaac atatttataa aggatttgtt aaactgtcag gtacaccttt tataggtgag
    21061 caagaagatg ttgatggaat aaatagaaaa gtatggttat ttcctttgaa attaataaat
    21121 aatataccta tagaaaaaaa tctattagag tataataaaa atcttaaatc taaaaaagct
    21181 agaaaaatga ctcaattaga actaaaagat aatataaaaa ataaaaccat ctacaagaac
    21241 tgttatatca aaaccatatg taagagatga gctagtttct caatatgcaa aaaatagagc
    21301 aaatgagatt tgtgatctat gtggttctaa tgctcccttt aatgctctca tggtaaccca
    21361 tacttagaat atcaccatat taagtggctt tctgatggtg acgaagatag tttatataat
    21421 actgttgcac tttgtcctaa ttgtcataaa aaaatgcata tatgtaattt aaatgaagat
    21481 atacataagt tattagacaa gataaaaaat tacgaaaagt aaattagtta aacaaatata
    21541 ataaatttaa aaactaggat ctgaatattt ttctaattca gatatcctac ctactgaatc
    21601 tatttgaaaa gcatagaaat ttttcttatt tacaagaatt gctgaatctg aatcatctat
    21661 tttataagta atcccaaaga aataacattc gtccaaatat gtttgtgcaa aattaggtaa
    21721 agaatctgta ttttctatta aatatgcttc atatttatcg cctagaactt tattagcttt
    21781 ctttaaagct aaatcatagt tactaacttc tgttccatct ttattgtaat aatgccaact
    21841 atctcctaat ttaatccacc catatttctt tattccattt gatacatcta tacattgttg
    21901 aattatacta ctattttcta tactaatggc agttattttg gaactaccct ctaatatgtt
    21961 cttatcacta tttgtatcta ccaaaataat aggatcattt ttagctattg tagaaccaac
    22021 aagtgcatac actaaatctg ttccacttgc tatataaaat tcttttgctc cattatagaa
    22081 cttatttact attttcttat tagtatcgta tctatctata ccacctaatc tagttgaatt
    22141 agtatcattt actaagttat cactcattga tgaagtacca cctattgcat aactttctat
    22201 tccaggctaa tattaaagat atacaacata gattagggca tgctaaaata tcaacaacta
    22261 tggatacata ttcacatgta actaacaaca tgagaaacca gacagtaaat atttttgaaa
    22321 gcattgtaga gtaaatttgc caccgaaaaa taattacggt ggcaaaccgg tggcaaaccc
    22381 acctttatag catcatatag atagctgaaa gcctcctatt ctctaacaag tttaactata
    22441 gtctcgcaat gaggcgtatt cggaaacata tccatacact taaccatcct aatctcataa
    22501 ccatatctct taaaatcaac caaatccaca accaaagact taggattgca agaaatataa
    22561 acaatctcct ttgcaccaaa tccacaaata tccctaatag catctttatg aatacctggt
    22621 ctaggagggt caacaataat caaatcaggc ttgtccttta aatccttaac aaccttagcc
    22681 acatccccag caataaactc acaattagta agcccattca acttagcatt ctcattagca
    22741 gcaacaacag cctcctcaac tatctcaata ccatacacct tcttagcagc accagccata
    22801 acctgtccaa tagacccagt tccactatac aagtcaaata caaccttatc attgtaatct
    22861 ccaataaaat ccctagcaat actataaaga acttctgctc ctttagtatt agtctggaaa
    22921 aatgaaaatg gagaaatctt aaacttaaga cctaaaattt cttcttgtat ataatctctt
    22981 ccatataaaa ctcttaactc atcacattgg accgcatctg ctaaaccatc attaatagta
    23041 tgaagtaccc ccaccaactc agattttaaa tcaatcccta aaagcatatc tttaaactca
    23101 ttcatatcaa aatcttcttg agaagaagtt actatattaa ccataatctc attagtatga
    23161 atcccttttc taactacaag atgtctcaaa tatcctttat gattcattgt tctatagtaa
    23221 ggaagctttt tttcattaaa aaactctaca ctagaaacta atatctttga gaagtcttca
    23281 tcaaccaaca tacactcctc aacagtctgt atatctatat gttttccttt tttatgaagc
    23341 cctaatgtca aaggtccatt ttttacttca tctccaaaag tgtattccat cttatttcta
    23401 taatatttgt tttctggact tccttctatc cctaaaaatt gaaatccaaa taaatcttgc
    23461 tttaaaaata aatccataac ttgtttttct tttatttcca attgtttttc atatggcaca
    23521 gacagtaatg tgcatcctcc acactctcta aagtgcttgc aagcttcttc agtttcaagt
    23581 ggtgagtttt ctaatagttc tatcatctta acttcagctt tcttacttct aactttttta
    23641 actccagctc tcaccttttg accacttatt ccacccttca tatggataac tctatctcca
    23701 acttggctta aagatgtacc accaaattcc atcttatcta cttcaaattc tataacatct
    23761 tttttcttca cagacattcc tccagtttac tatagtatct ttattatctt tcttcaatca
    23821 attttatttc ttcatctgtt aactctctat attcacctaa ctctaaactt tcatccaatt
    23881 ttaaattacc catagacaat ctttttaagt atactacttt tttgcctaca ctttcaaaca
    23941 ttctttttac ttggtgaaac ttaccttcat gtattgtaag ctctatctct gattcatcat
    24001 cactctttaa gatatttagc tgagatggca tagttttata tccatcatca agtactacac
    24061 cttctaaaaa agcttctaca tcttcttcag taactactcc atcaattttt gcataataag
    24121 tcttaggcac atgcttctta ggagataaaa ctctatgaga aagctttcca tcattagtta
    24181 aaactaataa tccctctgtg tctttatcta atcttccaac aggaaatggt tcaaaagcta
    24241 agtatgataa atcaattaaa tctaagaccg ttgggtcata tttatctgta gttgccgata
    24301 catatccatc tggtttattc atcattaaat atatatactc tctatatata acttcttctc
    24361 cattaaacaa tatctcatca ttttcagtgt ctacttgagt tcctggattt gaaacttcac
    24421 ttccatttac tactacagac ccttgcttac aatacttctt tatttcactt ctacttccat
    24481 agcctaaatt tgaaagaatt ttatctatac gttgcttttt agccattaaa aatgctctcc
    24541 attctcataa tatttttctt tttcaaatac tgtaaatgct aaatccatac tttctacatc
    24601 taaattagtt cttatactat cagttattat tcttgctact gtatcttgta cttcttgtcc
    24661 cctgtcaaac caagctatct caacaaaagg atatacatct gctattttac catctcttat
    24721 tgcaactgac tttatacatt ctatttcaaa gtagtctctt ggacatttta cagcttcaac
    24781 taaatcatct atcatttttt cacttatttt acatatatca tcctcattaa ttcctcttat
    24841 ttttatctgt ggcatagttt acctccttta ttttaaattt ttagtgaatt atcatccact
    24901 taattacctt cgataacgtc tgaagtggta gcttcttggt caagataact attgttatca
    24961 gtatctccaa actaataagg tagttcctac ccttatagtt agcattatat agctaagttt
    25021 cctgaattgt ttatattctt tattatttta tttaatccta ttgtcttcta tttaacatta
    25081 tacttgtaat ttatagttat tacaatttac tatatacttt ttttgattta acgttataat
    25141 ataagtgatg ggtaaatttt aaaagttaat aggaggagtt taaaatggca ttaattacta
    25201 caaaagagat gtttaaaaaa gcttacgaag gtggatttgc tataggtgca tttaacataa
    25261 gtgacttaga acaattacaa ggtgttttaa aagctgctaa agctaaaaat tcttatgtta
    25321 tgatacaagc ttctatgtca gctgttaaat atgctggacc tcatacatta gttgaaatgg
    25381 ttaaggctgc ttctgatgaa ataggtgtag acgtagctct tcacttagac catggtccaa
    25441 atatggatgc tattaaaact tgtattgatg ctggtttctc ttcagttatg atagatggtt
    25501 ctcattttga ctttgaagaa aatgttagaa taactaaaga agctgttgaa tatgcacact
    25561 ctaaaggtgt tgttgttgaa gcagaacttg gtgttctagc tggaacagaa gatgatgtta
    25621 cttctgatgt tcacaagtat actcaaccag ctgaggcagt tgagttcgtt gaaagaacag
    25681 gtgttgattc attagcaata gctattggaa cttctcatgg tgctttcaaa ttcaaaggag
    25741 aagctaaatt aagattcgat atactagaag aaatccaaag caaattacca ggtttcccaa
    25801 tagttcttca tggtgcatct gctgttgacc aaaacgctgt tgctacatgt aatgaatttg
    25861 gtggaaatat agctggtgct aaaggtgtac ctgtagatat gttaagaaaa gcatcttcta
    25921 tggctgtttg taaaataaac atggatactg acttaagact agctatgact gctgctatca
    25981 gaaaattctt agctgaaaat ccaaaagaat ttgacccaag aaaatacatt ggtgctggta
    26041 gagatgctat acaagctgta gttgaaagca agatagatga tgttttaggt tctgctaact
    26101 ctataaacta atataacttt taaatattta taaaagaaaa gagatgactt aaagtaatta
    26161 aatttatttt taagccatct cttttaagtt gtatatatct ttttatataa acaaatatat
    26221 gttatttttt tactgtattt ttaactatgg taccatctct aaacccttta gctatttctt
    26281 ccacattcat ttttacatta ttagaagtat ctgcaaatga tttatttgta agcaaacaaa
    26341 atccacctaa accaatcagt accgttaatc ataaagccat aaactatttt tttatgatta
    26401 ttatatgctt ttttgttatt ttctaaataa taccataaaa atgtttatgt gctaatacaa
    26461 aaacactttt agcgataata ctccttactg tgattggtaa gttataaatg tgttattcaa
    26521 tctagtagat tcttactttt ttagaagact ggaacaaatc atatgagtac acatctatag
    26581 tgtttctacc aaaaaacaaa aaaatatcac tggaatcaaa acctccagca atatttaata
    26641 ataaaaaata tatttacata aatctatgta cattttccta ataaagtata tttcatcaat
    26701 tctaattact ttaccaaact aacaactata catgaatatg tccactcttt atctttctat
    26761 ggatggtaga aggatatata cctataactt cagcagcctt tgttattgaa ccatacttat
    26821 ttatagcctt acttatcatt atttggtcca ctattttata tgcatcatta agattcataa
    26881 ttccatttac cactattggt gataaatcat ctgtttcatt atcaatcata tctaaattta
    26941 taagcatatt aaattcatct tctccaatta tatttttagc tgataatact acgaatcttt
    27001 caataatgtt ttttaactct cttatgtttc ctggccaaga atattcttct agtaactcaa
    27061 taaccttagg tgaaacttct acttctctat tatacttttc attgtaaagt tttaagaaat
    27121 aatttactag tggtactata tcttcttttc tttctctaag tggtggtatt tttactggaa
    27181 taacactcaa tctatagtac aaatcttgtc taaatttaag attatttcta aggtcttcat
    27241 gagaaatatt agtagcactt atatatctaa catctatctt tataggctta ctaccaccta
    27301 ttctagtaat agtattttct tgtataactc taagtaattt tttttgcatc tgcattggta
    27361 attcacctat ctcatccaag aaaatagttc ctccatttgc ttcttcaaaa agtccctttt
    27421 tgcctttttt cttagcacca gtaaaagaac cttcttcata tccaaaaaac tctgactcta
    27481 ataattcatt tggtatagct ccacagttta tagctataaa aggtttgtct cttcttgaac
    27541 tatacttata tattgttctt gctattattt cttttcctac acctgattct ccatttataa
    27601 atatagaaga atctgatgct gcagctctct taacaacttt ttttatattg tccataatct
    27661 tactttgact tatatattct gtgtcttctg atatatcact atattttatc tgagattcaa
    27721 gcttgataac ccttgaaata tctcttcctg ttagtactcc tcccttaagc tttcctttag
    27781 aatcccatct tggaactgct gtgtatgcaa taagcttccc atctgggtaa acgatatttc
    27841 tataaatctt tttcttcact ttaagcatgt ttaatattat tggttcttca actaatcctt
    27901 gtcttacaag gtctgttata tttctaccaa gtacctcagt tcttttgaag ggtaatatct
    27961 cgtcactgac agtattcatc ttttcaatta ccccatcttt gttaaacaca acaacaactt
    28021 catctatatg ctctattata tcttcaatta ctttatcaga tattagagac ttctcaaata
    28081 aataaactac attattttta ttattattat ctttcatatt gtatatatgt gcagtcatcc
    28141 ttaactctct gaaagctatt ttctttttac tatctgtcag tatttctgtt ttgtcaaaat
    28201 ttgaatctaa ttcatttata tttttaggct tttttatatc tagaaaacta aaaatactat
    28261 ctattagatg attacagtat attatttcgc ctgattcttt acataaaatg gctggatttt
    28321 ctacatgttc tataagccct attaaattat tatccattaa tattcgcacc tttcattaag
    28381 taatttattg aactacatac aaaatttatt gtttgcttac aataaatacc atcagcacat
    28441 ataatcaact ccttataata tttgtctttt caagtagttt ctttcattaa aacgtaacca
    28501 agatataatt ttaatgatta tagtttgtta aaaatttcat tttgctttta attgtatttt
    28561 atcacatatt tagtaattat ttgtctattt aatacaattt aattaaattt aagatttatt
    28621 gaaaaaacaa agataatcct tacagaatat gactcacaat ttgtaagcaa tatacatata
    28681 aggattatct agattatctt gtattataaa attttattca aacagacttt ttaataactg
    28741 acaaatacgc actagcaata acttatcaaa gggttaataa ttatgttact aactaataag
    28801 acttattcaa tcagtaatat ttatatagtt tgtatctatt aagcttttat agcttctaat
    28861 aaatcatcaa cgctatctaa tttttctata agcattggaa ctatttcatg taagtctcca
    28921 actactccat agtcagcgat ttctaaaatt ggagctgctg ggtttttgtt tatagcaatt
    28981 atgaaatctg atgattgcat acctgctaaa tgttgtattg ctcctgatat accacaagct
    29041 atatataggt ttggtttaac agtagttcct gtttgaccta cttggtgaga atggtctatc
    29101 catccagcat caacagcagc acgagaagaa ccaactactc cacctaattt gtcagctaat
    29161 ttcttaagca tttcaaatcc ttctggtcca cctaatccta gaccacctga tactataaca
    29221 tttgcatctg taagagatac taaatctttt ttagttttaa ctgtttctaa aacagtagtt
    29281 cttatatcat cttgagttat tttgtaatct aatgctataa cttcaccagt tcttgtttcg
    29341 tctttttcag ctttatccat aacaccaggt ctaactgtag acatttgagg tctatggttt
    29401 ggacaaatga ttgtagccat tatgtttcca ccaaatgctg gacgagtttg ttttatcttc
    29461 ttatcttctg ggtctatttc taatttagta cagtcagctg ttaatccagt tccaactctt
    29521 gaagctattc taggtgctaa gtctctacct atatgagttg ctccgaaaag cattatttct
    29581 ggttttattt catctattgc atcttttatt acttttgtat atgcatcagt tgtatatttt
    29641 tctaaaagag cgtcatctgc aacataaact ttgtcagctc caaaagtgat taattcttta
    29701 gctaatccat caacatcttt tcctaataat attgcacaaa gctctgcatc tacttcttta
    29761 gctaattttc ttccttctcc taataattcg ataactactg gagctatttt tccttctctt
    29821 tgttctgcaa atatccatac gtttttataa gaacttaaat cttttatatc attcatagtt
    29881 tgtactcctc caacttatat aatgtgcttt tgttttagac cgattattat tttactagct
    29941 atttcatcag ctttaccttc taagatttct ccttttcctc ttggttcagg agtaaatgat
    30001 ctaaatactt tagttggtga tgcttttaaa ccaacttctt ctttatttac atctaaatca
    30061 tcaattgtcc aaacttttac atcatgttta tatgctttta ctattttatc aacagacatg
    30121 tatctaggtg tatttaactc ttttactgct gttaaaagta caggtgtact tacttttatt
    30181 aattcatatc catcttctaa ttgtctttga actattatat cttttccttc tattttaaaa
    30241 tcttgtacat atgtaacttg aggaatgtct aatttctctg caatttgtgg tccaacttgt
    30301 gcagtatctc catctattgc ttgtcttcct gcaaatatta tgtcatagtc acctatttta
    30361 gatattcctg ctgcaatagt atttgatgta gcccaagtat cagctcctcc aaatgctcta
    30421 tcacttaata atattgcatc atcagcaccc atagctaaac actctcttag cataaagtct
    30481 gcttgaggag gtcccattgt tataactgtt atagttacat catcatactc atctttaatt
    30541 tttaaagctt cctctaatgc atttgcatca tctgggttta atatacttgg aactccatct
    30601 cttataagag tacctgtttc tttatttatt cttacttcgt tagtatctgg aacttgtttt
    30661 acgcaaacta atattttcaa agtctatacc tccaatttca ttagattatt tattatttta
    30721 atacgtttga tgaaattacc attttttgaa cttctgatgt tccttcgtat attgatacga
    30781 ttctagcatc tctgtacatt ctttcgattt cataatcttt tataaatcca tatccaccgt
    30841 gaagttgtaa tgctttataa gcaacttcat ttgcaatttc tgatgcatag tatttagcca
    30901 tagcagattc ttgagcaact ctcattcctg catctctctt ttgtgctgca tcataaacta
    30961 atcctctagc tgcacaaact tttgtttcca tgtcagctat agtaaattga gtattttgga
    31021 atttagctat aggcttacca aattgaactc tttgttttgt atatttaaca gcttcatcta
    31081 aagcaccttg agctattcct aaagctaagg cagcaacacc tattctacca acttctagag
    31141 tacccattgc tatcttaaat ccttgacctt cttttccaag taagttttct tttggaactt
    31201 taacgttttc aaatattaag tcagaagttt cagttcctct tatacccatc ttatcttcat
    31261 gagctcctgt tgagaaacca tcccatttac tttctactat aaacgctgat gttcctctaa
    31321 gtcctttact tctatctgta actgctatta ctatagctac atcacagaat ggtccattag
    31381 ttatgaaagt ttttctacca tttaatatat agtggtctcc aactaattct gctgttgttt
    31441 gttgtcctgc agcatcagaa ccagctcctg gctcagttaa accaaatgct cctattaatt
    31501 cacctgttgc tatacctttt aagtattttt gtttttgctc ttcagtacca ttgtaaagta
    31561 ttggtaatga agcaagagaa gaaccagctg taacaaaagt agctgttgaa gcacatcttc
    31621 tagctatttc ttccattact atagcgtaag aaacatatcc tgctccccca ccaccatact
    31681 cttctgggat attactgctt ataaattttg catcagctaa ttttttgatt aattccttag
    31741 gcattacacc tgttttatcc atttctgctg gtaaagtatc taattcttta ctaacaaaat
    31801 ctcttactgc ttttcttaaa agttcttgtt ctttgttata taacatagct tcctccaatt
    31861 ttcatatttt atagtaaatt tattttaatg aacttacgct aaactcatca tctcagcaaa
    31921 agtttgaata cgagttctgg cttgttcatt attctgagtt tgttggtcga tttcaacata
    31981 taaagtaggt attccactat cttctatatc ttttctaact aaaggataat cgtattcttc
    32041 tgggtcacag aatttcatca tacagaagat aacaccatct atatctttct ttttaacttc
    32101 atctactata agtgacccac gttttttctt agggtcataa gctaatgaac atccttctat
    32161 gtttgaccat tgtcttgcta atctttccaa cgcatcatca cctgctggta catctgttct
    32221 gaattgtctt gtttcttgtg ctaagtcatc agctacaact gatatattgt tgtcttctaa
    32281 aatatctaat atatctttag aatcagctaa tatacctgtt aataaaactt tctttccaga
    32341 acagacttct tctggcatag catttaattt tgctattaaa tctttcacta gtttagtgtg
    32401 ttcttctttt ctcataaaga atccactctt aattactaag cttcttattg atggttttat
    32461 agtattagaa tgtttataag ctacttcaac aaagtctctc atagtttttc tatgttcatt
    32521 gtaaacttct atactttcat gaatttttgc ttcttctatt tcatatccac atatttcttc
    32581 aagctctctt tttacgcctt tgtactcact gattaagtat tttacaccag cttcaagttt
    32641 tctattttgt gggtgtacta atgatatata ttttatatga ggtactgctg atttccagtt
    32701 ttgtcctaaa caaattaatg tatcacacat acctggtata ataactccag ataattcatc
    32761 ataagcacct tttaatccat attctaaaca tgattgcatt attgaacatg caaatgcagg
    32821 gaaatattgt ttagctaaat ctaattctgt ttgtcctccc catataccaa ctggaagcat
    32881 tccagctgca tgtataattt cttctgggca ataaactggg aaacaaccta tagctttttt
    32941 accagtttca cttttatatt tttttacagc cgcatttgga ttttcaacta cttctttcat
    33001 tttagataaa atagcttcca ttatatctca cctctattaa gtttttttct ttcttccatt
    33061 acttcaacta aaccttgaat tcttgtttca aattgagcat tagtgaaagc tctagggtct
    33121 gcttggtcac catcaaatcc agcatatggt aatccagttt cttcagctgc tcttctttgc
    33181 atttcatatt gtattaaact cataagttta caacttctgt tcatatgata aaatgctcca
    33241 tcacatttac cctctattaa agaatcaact ctatattttg tcatacggtc tagatttaca
    33301 ttgttaaaca tagtactata tgctactgcc attccatcta aatcattaac ttcatattgt
    33361 aatgcccaag catgtgggta aacactacct gtcatgttaa ctccaaattt agctaatgtt
    33421 ttcatcttgt atcctatata tggccaacaa ggtatacctt ccatcattat tctgtatttt
    33481 tcttctcctc tgaaagaaga tttaccagtt ttcatgttgt cctctaattc ttctataagt
    33541 aacttaaatg cttctgtagt ctctttttta cctctagcac aaactattac agccatataa
    33601 gtaaataagt caaatccatt cattggagaa ggagaagaat ctgctggtaa actcatagaa
    33661 tacttccata gtcttccgtt ttcagctgat attttcatta cctcttcaaa tttcttaggg
    33721 tcaaatttct ttcctgatat aatttctagt tgttttatag cttcttcaaa ttgagcttta
    33781 atataatcta ttcttgattg agtaacttca tcttcattat tgaaagttgt atcaatcatt
    33841 attaaaggta tatctaattc tcttgaaata ttttcatacc attttataac ttggttacat
    33901 atattgttac agcaaagtag gaaatctgga gctggcatat ccaaagcttc acatccacca
    33961 ttttctaaaa gaccaaaatt tgttcttgca tatgcacata ggtcaataga atatccttta
    34021 gattcagcca tttcacataa ttctaaagaa ccttttttag ctgctactcc agccgcttgg
    34081 ttttctggat ataatacgtt taagtcaaat acttctgcta attcttgagg aaatactgat
    34141 gttgaccaac ctacaggtct tccttcttct ttagctttaa atgcatttgc atattgttca
    34201 gctaataaat cattaattac tactctagct tctttttttt cagacatttt catccctctt
    34261 tttatatatt tttcacttct ttttgtgatt cttttgcttc atcaaaagca tataacgctg
    34321 ctcctaaagc accagttaat tgaggtatat caggtacaat aatttctgtg ttgatttctc
    34381 ttgccatagc tcttacaata ccactatttc tagcaactcc accaaccata actacatttc
    34441 tttgtactcc tattcttttt actaggctag aaactctctt tgctactgaa gtatgaatac
    34501 ctgctactat atcttcaatt tttgcatttt cagataaatg tgatataacc tcagactctg
    34561 caaatactgt acatgtactg cttattgata cttcattttg agaattcata gatatacttc
    34621 cgagttcaga tacatcaacc tctattattt ttgccattac atctaaaaat cttcctgtac
    34681 ctgcagcaca tttgtcattc ataagaaagt ttagtagtct tccattatta tctaacttta
    34741 atacctttgc atcttgacca cctatgtcaa taatggttct tgtctctgga attatgaaat
    34801 ttactcccct agcatgacag cttaattcac ttatttgctt atcagcatct gaatagttca
    34861 ttcttccata tcctgtaact acaacttttt taatatcttc tcttgcaaga cctgtcttgc
    34921 catataattt ttctaaaact cttgatggtc cagtagtccc agtaccagag gatattgttt
    34981 cagaagctac aatatcttct ccattcttta agattactcc ctttgatgca gttgaaccta
    35041 tatctaatcc cattgtgtac atctttagca ttctcctttt aaaaaatcta gaattactaa
    35101 ttaatatctt acaactttac tatctttaaa gttatttatt ttctcttcat catagcctaa
    35161 agattttaat acttctacag tatgttgacc tacttttggt gctggtgtat attctttaat
    35221 tccttcattt ctaaacataa ctggagtatt aactaagaca cctgtatttc cgctatcata
    35281 tgttttctta aataagaagt catttgccca agcttgttcg tcatctaata aatcttcaca
    35341 gctttgaatt ttttcaaatg gtaaatctgc ttcttctaat aaagctgacc actcgtctag
    35401 tgttttttct aacatagctt ctccaactat tttaactaaa tcttcaacat gattaaccat
    35461 tgaatctatg ttattgtatc tatcatcttc taatatatat tctctattta taaccttaca
    35521 gaatttgcct aaccacttgt tgtattgtat taaagctaat tgaatccatc ttccatcttt
    35581 acatttatat gtagtcatta atgggctgtt tggattttct cttgataaag gcatttcatt
    35641 tccgtattgt gctgttgtta tcattgttcc cattccatat atagctgtat ggaaaagact
    35701 tactgttact ctctcacctt taccagtttg acctttttta tgtaatgctg ctaaacttcc
    35761 tgccgctagt gctagacctg cataatggtc accaaatcct gctgctgtat ttgctggaga
    35821 tgttcctttt tccataacag attggctaac tcctcctctt gcgaagtatg cagtatagtc
    35881 aaatcctggt ttatctttta aaggtccttt ttcaccatat cctaatattt gagagaatat
    35941 taatcctgga tacttatctt ttatttggtc ataagctata cccatttttt ctaatgcttg
    36001 aactctaaca ttagttacaa atatgtctgc ttctgataat aatttatgta atatttctac
    36061 tccttctttt gattttacat taatacttac acccttttta tttccatttt ctaattcaaa
    36121 catagggttt tcatcatctg atgctggaga tttaaatgtt ccacccataa ctcttattcc
    36181 atcaccttct ataggttcaa tcttaataac ctctgcaccc cagtcaccta acatttttgc
    36241 acaacatggt gctgcaatga aacttgaaag ttctactact ttaactcctt ctaaaagcat
    36301 aacgttttcc tccttaatag tatcaattat aaaatttcaa ttaaatcact cataaaatac
    36361 tttttctgat attaactgtt tgatgtcaaa gttcctaatc ttatctaaaa taacttaaaa
    36421 attattaaaa ttatttttta ttgttttatt gtcttacacc tatattgtta agcatttatc
    36481 gtgccaactt tatatttaat caaaatatcg cttgatttga atgtttttta acaatatcca
    36541 atcaaataat ctttttcata tcgtggcatc ttgcaactat ccattgcatt ttgctattct
    36601 ttctatctct ataaaagttt tttttatata tttttttatg aaaaagcttg acatttcaaa
    36661 aaaagttttc attgctaaac tcaaaaacac atgttatcat tgtaattaat cagcaagtta
    36721 gttaactaat ttcaaactta gataattttt taataatatt taatctaaaa aataacaatt
    36781 tctttgataa atttttagag taattattac attaaataaa aaattactaa atatcaaaat
    36841 aacacaggga aaacaatttc aaagctaaat ttttaacctt aaaaattttg tataaaaaat
    36901 atagccttat ttaatacata ttattattta atacatatta tttctaaatg aaaaattacc
    36961 ataataattt aataattaca ggagggtatt gatatgaaaa tactagtatt tggagcacgc
    37021 gattatgaag aaccagtaat aaaaaaatgg tctgaagaac ataaggatgt tcaagtggat
    37081 atttatcctg aaaacatgac tgaagaaaat atagttaaag ctaaaggata tgatggtata
    37141 tctatacaac aaactaacta tatagataat ccttatattt atgaaacttt aaaagatgct
    37201 ggggttaaag ttatagcttc aagaactgca ggggttgaca tgatacattt tgatttagtt
    37261 aatgaaaatg gacttattgt tacaaacgtt ccttcttatt cacctaatgc aatagctgaa
    37321 ttagctgtta ctcaagctat gaacctttta agaaagactc ctctagtaaa gaaaaaagtc
    37381 tgtgaaggtg attaccgttg gatagctgaa cttcttggaa cagaagttag atctattaca
    37441 gttggtgtta taggtacagg aaagataggt gctacttctg caaaattatt caaaggccta
    37501 ggagctaatg taattgcatt tgaccaatat ccaaatagtg atttaaacga tatattaact
    37561 tataaagatt ctttagaaga ccttctaaaa gaagctgacc ttataacatt acatactcct
    37621 ttacttgaag gaacaaaaca tatgataaat aaagatactc tagctataat gaaggatgga
    37681 gcttatatag taaatactgg tcgtggtggt ttaattaaga cagaggactt aatagaagca
    37741 ctagaatcag gaaaaattag agctgctgcc cttgatacat ttgaaactga aggattattc
    37801 ttaaataaaa aaatgaatcc aggagaatta actgacccag aaataaataa acttctttct
    37861 atggaacaag ttatattcac tcatcacctt ggtttcttca ctagtacagc gattgaaaat
    37921 atagtttatt ctagtttaag tagtgctgta gaagttataa aaacaggaac tgctactaat
    37981 agagtaaatt agtattttat aaatatattt tttcattaat tagctattat ctaacaaaat
    38041 agcctttaat ttcccaagta tgagagagtc agctcaatat atattgagta gactctctta
    38101 tattattttt tatattaaac ttatactctt cttattcata ccaaattaca tttatattaa
    38161 tttattctaa ctactcttac tctacatata ttttacccat ttttactttt ctaatttttt
    38221 ctaattatat acatttgaat gggtacaatc tgtattttac aaaaaaaaca cttaacaaac
    38281 tatgaaaatt gtatgattaa tattaatata tttataagaa aacattacaa ttatgttagc
    38341 tctggatttt tagggaggga gtatattgga aaaaatgaat aaagttactt ctaaaaaaac
    38401 tacctatatt gttacttcag cattatttgc atccataata tgtctgacaa tagcatatat
    38461 actacatatc ccagttggtg gaaacaatgg atatgtccat ataggagatg cttttattta
    38521 tctagctgca actattttgc caacaaacta tgctatagct gcttctgcaa ttggtgctgg
    38581 tctagctgat ttatctacag gtgctgctat ctgggtaata ccaactataa tcataaaacc
    38641 aatacttgta ttatttttca cttctaaaag tgacaagata ataaataaga gaaatatagt
    38701 tgcttcgatt gtagcaggta taataggatt agttttatac atgtttgctg aaggtataat
    38761 tattggaagt tttacaagtg catttgtaat gagtttactt ggcttattac agccaatagg
    38821 aagttttatt gtttttataa tcttaggtat ggcacttgat aaacttgatt ttaaaaaacg
    38881 ttattttaat taagaattta aatttatgga gggaaaatta tgaatatctt atatacaatt
    38941 gaaaatagta tctatgtgaa tataactaat acatgtccat gtagttgtgt tttttgtata
    39001 agaaatgaaa aagatgaagt tgcaaatagt ggtagtttat ggttggagca tgaaccaagt
    39061 gtagacgaag taaaagaagc cttcaataaa tacaatttag acgattatga tgaaatcgta
    39121 ttttgtggat atggcgaacc attaatgaga ataaatgaat tgatagaagt agcaatgttt
    39181 ataaaagaaa aaagtagcat aaagataaga ataaatacaa atggtctaag tgatttaata
    39241 cataacaaaa aaacagctat tatgttaaaa gatgttatag atgcagtatc aataagtctt
    39301 aatgctccaa ataaagaagc ttataataga gttactcaac caaagtttgg agaaaaatca
    39361 tttgattata tgttagattt tgcaagagat tgcaaaaaat atataaaaga agtggctttt
    39421 tcagtagtag atgaaatatc tccaaaagaa atagaagaat ctaaacaact agcaaaaaaa
    39481 cttgatatac cattaagagt tagacataag aactagcaag taaaattgta aaacattaat
    39541 aatcacctga aaggtgtttc aggtgattat ttctcttgta ttaacatttc acaaaataga
    39601 tttcatacca cactaaaaat gtgtaaatcg tccaaatctt tctccaatta ttagaatttc
    39661 cactaatgta gtcattaaaa atctcattaa tctcatctat gttaaagaat ttatctgcta
    39721 tctcactatt gaatttatct cggatatcct gattatattt gtcatcagcc atccatatac
    39781 ggattggtac aataaatcct aatttattcc taaaagcaat ctcttctggt aatacttttg
    39841 atgcagcttt acgaaaggca attttattct ctccaccttt cactttatat tctgatggca
    39901 ttcttgatgc aatatcaaag attcttgtat ctgtaagggg cattctgact tccaatccaa
    39961 ctgcagtact cattttatct atattaaaat aaatgtctcc ttccaaccat atttgaatat
    40021 ctatatttga catattagta agtgtatcca gttcctctgt ttcttcataa attctttttg
    40081 tcagtttaat aggaagcaca tcaggattgt atttcttaag aatttttcgc ttctcatctt
    40141 ccttcataat gttcgtattc ccaatataaa atgtctttag attctcccca taacactttg
    40201 ccttatgata tacattatat ccaccaaaga actcatccgc tccttctcca gagtaacaaa
    40261 tatttgtgtt ctcagctgct gccttgcatc caatagcaaa aacaatagca gatgcatctc
    40321 cagttggttg ctccatatgg tacattacat aaggtactga cgcaaaatac tcttcaggtg
    40381 taattatata tctcgaattt ttacatccaa gaatatcagt tgtctgttgt gctaattttg
    40441 attcatcaaa ccactcttcc tcataaccac atgagcctgt tttttctata tctgacattg
    40501 ccaatatata agatgaatca acacctcctg ataggaataa ctctgcagtt tcatcctctg
    40561 attttatctc tggcataatt ttttgaagtg ttgtatgaat ttcatctgtc cattcctcaa
    40621 tggacttgct gtagtcagga tgaaattcag gtttccaata acgctcaata catactgttt
    40681 tgttctgata gacaaggtaa tgtcctggca taagcttttt tactccacgg aagaatgtat
    40741 tttcacctgc tacatatgta aaagacatat acatctgtaa catttcttca tttaactctt
    40801 tcacaaatcc tggttgttcc ataagcttac gaatagatga actatagaga agcttcccat
    40861 tttcagtctt ataataatag aaaggtttta ctccaaactg gtctcttagg caaaaaagct
    40921 tcttttccac tgtatcccat agtgcaaaag caaacattcc atgcatgtga tttgccatat
    40981 catatcccca ggttttgtat gcttctacta aaattgctcg ctcacgctca tctctaccta
    41041 aagaagaatc gattcctagc tcctcacaga gaactttcca atttctaata tgtccattgt
    41101 attctaaaat ttttatcata catgtatctt ttcgtgttga atacttttct tctaagttta
    41161 tcatatgtgt atcctttcat attaaaacat ttaattctta aatttattga ttgtttttat
    41221 ttatatttat tcacttataa tcattgaaaa tctacttttt tcaaagtaaa ctctttttta
    41281 attagtgcta atatgctctt tgttaaggtc accaatatga ttattaatta ttatcagtgt
    41341 tataacattg aattttttat ttttcataaa tattgccctc ctttaaatta ttagctaaat
    41401 ataatatatc ttatgttact tacatattct ttaagaaatg ctgaagattt tataaagttt
    41461 tctgtagtat aattaattaa aaatacaatt ctagttataa agcatatttt ctattaaaca
    41521 aaaaatagtt aaaataaatt cataataaca taaacttatt ttaactattt gtatatttta
    41581 gttataaata ttgacttaaa tttttaacag gatacactca taaaataaac acgataaaca
    41641 ataaaataat atatcttagt ttctttatat actttgtctt ctttcaattt tctaccatgt
    41701 agacggttaa gataatatta gtaattcact ctactgctta actcgtgcga tatggacaac
    41761 caagaaagct atttcctcat ttgttaactt ttttccatat ttcttttcta aaaaatctct
    41821 aacttttaat gcaattgaca tttcttttgg atttgacctt ttcatttgat tgaataataa
    41881 atcatctaca ctacttaaca tgctatctga aaaaaatctt tccacaaaaa attttatatg
    41941 tgttataaat ctcatataat gcatactttt tttatctaag gttctattca aagaaaaaac
    42001 aaaaatatta attatttctc caattacttt ggcatattta atcgtatcat atgaatttcc
    42061 atctgaagcc atagcgtttg caaaatgaaa agcaatattg gctgcttctt cttctggtaa
    42121 ttgaatgccc aatctctctt ctaccatgta aattgcaacc attccaacct taaactcatt
    42181 tggataataa ttttttattt cccaaaatac tcgatttgta atttttattc ctttacgcat
    42241 cctttcaatt gcaaagttaa aatggtctgc taatattaag tataagtttt tattaaaaga
    42301 tgagttcaat aatttttctg cctctactat tatttcctgt gttatcttta aaatgtcgac
    42361 agaaatatca tccattaatt ctaaaaattg ttttgatttt gtattttcaa cagggacaaa
    42421 catttgatta tcattggaac cacaaatata ttctcctgtt tttttaccat atccaattcc
    42481 tttccctagc aaaataaatt cattatcatt tgcatcatga actaaaacaa cgctcgagtt
    42541 caaaactttc tttattatgt agttcatttt atttgctcac cttctattgg tcatttaaaa
    42601 tctatactat tattttcaat tactttttta taccaataaa aactatcttt cttatatcga
    42661 ttatatgtcc cctttccata atcatcagca tccacataaa tatatccata gcgttttgac
    42721 atttgtttcg ttgattcact gaccaaatcg atacaacccc atgaagtgta tccccaaagt
    42781 tcaacaccat cttcaataat cgcatctaac atacatttaa agtgttcttt taaataatca
    42841 attctatatt ggtcatggac ttttttatct tcagttaaaa tatctttcgc tcctaatcca
    42901 ttttcaacta taaataaagg ctttctgtat ctatcatata attcaatcaa agatatgcgt
    42961 agaccaattg aatcaatttg ccaaccccac tcactcattt ctaaataagg attttttaca
    43021 gctaataacg tattccctga tgtaacatct aatccagttg tatcggctgc ttcacaagaa
    43081 gacatatagt aagagaatga aataaaatct actggatact ttttcataat ttcatcatcc
    43141 tgttcttctt ttactatttg aatgttatta tttttaaaat atgacaataa atatactgga
    43201 tactcaccaa aaacctgcgt atcactgtat gcataaatac ttctcatttt ttgttgggct
    43261 gccaaaacat cttctggtct acatgtatat ggataatatg ttaattttgt taacatacac
    43321 cctacttttg aatttggaat aatctcatgg caaatttttg ttgcaagagc actagctaca
    43381 aattgatgat gcatagcttg aaaaataact ccctcaaagt ttttatcctt aaaacggtct
    43441 cgaaccaaac caccagtagt gtatggatgg cgaatcatag aatcaacttc attaaatgta
    43501 agccaatact tcactttgtt tttatatctt tcacagatag tttctacata cctaacaaac
    43561 atattgataa cttgtcgtga ataccatcca tcatagttta aaacgatatt taatggtggt
    43621 tcataatgtg acatagtaac aagtggttca attccataac ttattaactc atcaaataca
    43681 tcatcataaa actgtaaacc ttcttcattt ggttctgtat catctccatt tggaaaaata
    43741 cgagaccaag caatactcat tcgatatgtc ttaaatccca tttctgccat cagagcaata
    43801 tcttctttat agtgatgata aaaatcacta ccgtgacgtt ttggataatt tacttcatct
    43861 tcaggatgtg ctaatccttc ttctatgtct cttgtcgtaa tttcattatt ggatttatag
    43921 tctttcacat ccacatcaaa gtgtgctttt gctacatctg atacagacca tcctttacta
    43981 cctaaattcc aaccaccttc aaattgattg gcagctgtag ctcctcccca aaggaatcct
    44041 tctggaaatt ttctcatact tatattcctc cctttacatc aaacaagatg cttccttttg
    44101 ttacattgcc ataagactga tttaacactt tatagtcata atctgcccca ttactattta
    44161 caatcataac agttgaatct aaattagcat gtgagatttt gtctaaatca aactgaatta
    44221 ataaatctcc ttcttttaca ttatcgcctg tcttaacaaa tgttttaaat ccatctccat
    44281 tcatacttac agtatttatt ccaatatgaa tcaaaatctc agccccattt tttgttctta
    44341 aaccaattgc atgttttgtt tcaaatagca tcacaacttc tgaatcacaa ggtgcgtata
    44401 aatttccatt ggtcggtata attgcaactc cttctcccaa agtcttactt gcaaataatt
    44461 cgtcactaac tttacttaaa tctatcactt ttccttctac tggagatact aatatattta
    44521 cttcttttcc ttctattggc tcttcttcaa caacattttc aattgatgac tgttctatat
    44581 ttgtatcttc cttccaaata attagtgtaa taataaacga acctaatatt gcaataacaa
    44641 aaccaatgct tgcaaaaatt aaattatttc cattgtttgg gtcaataaac atgctcatac
    44701 tagcaagccc tggtccaaca attacaaatc cttttactgt aaataaccct aaaaatatac
    44761 cagaaatcgc acttgacaat acaacaccta gtattgctct tttatgttgt aaagtaatac
    44821 cgtataaagc tggctctgta attcccatca atgcagaaat tcctgcagat aatgctgttt
    44881 gttttaatgt ttcatctttt gttcgcaatg ctactgcaaa acaaacacca ctttcagaaa
    44941 tgttgtgagc taatgaagct gtcatatata atgcttcata acccaacttt ccaattgtat
    45001 taattgcata aggtgttaat gctttgtgca ttcctgttgc aaccataaat ggaagaacag
    45061 cagcaagtaa tcctacaact aagaatccca ttttgttata taggaataaa ataatggttg
    45121 taaaaattgt cccaacatta tatcctaaag gacctaaaat agttagagta attggaacag
    45181 taattgccaa agacatcata ggaacaaaga aagttcgaat tggttttggt gaatacttgt
    45241 taaaaatttt ctccattatt gacaagaaag acacacataa aatagctggg aaaacctgtg
    45301 cattataggc aatacttgga atcgtaaatc caaataattc gacaccttca cttaaagcag
    45361 tcgtcgttgc tggaagtaat aagtatccaa cagcagcaat agctactaaa cgattacatt
    45421 tcaatacatt ggcagtagtt acagccacca tgagaggtaa gaaatagaat gttgcatctg
    45481 aaatagcaat taacaatgta tatatagtag aatctgattt taaaatatta aacattgcta
    45541 ataacattaa cagtgatttt agaataccag ctcctgcaat agcgaaaact aatggttgaa
    45601 aaatattaat aataaattct atgaatcttg ttcctaaatt tattttttct tcagttttta
    45661 tagcactatc atttgtatct aaagggcaaa cttttaaaat ttcatcataa acatcaacaa
    45721 cactatttcc aatgacaact tgaaattgtg ccctatcaac tatactcata acaccttgta
    45781 ctttttttaa agcatcttga ttgactttac ttctatcaat caacttaaag cgtagtctag
    45841 ttgaacagtg ttccaaagct agaatatttt ttgagccacc aacttgttca ataatgtcaa
    45901 tggcagtttt tttataatcc atcttgtaat ctccttctcc ataatttttt atgaatggcc
    45961 attcaagatg caaaaaaggc agaacctata taaacacctt gaaaaatcaa agcaatatat
    46021 tcgatcctgc ctgcattacc agtaacatgt cttctattta tactattttg tactaccata
    46081 ttaacatttg cctaaaagaa ttgtcaatac ttttttaaat tttctgatac taactaatag
    46141 cgcctttgta attcattttt catatcaatt aaagtaacag tagccaccca ccaattagta
    46201 tcaaaattga acctggtatt ttttctttta tattttcttt gaatataaaa tgagcaagta
    46261 ttaaagttat tatcatagat acttgagaaa atggttcagc tatactaagt tctagattat
    46321 ttaaagcaat taataacgct aaataagagt atccattaat agcaccactt aaaattgaaa
    46381 gccctttttt attattaaaa atctcccaaa ttactttttg tttcttttta aatgctaaaa
    46441 atataaataa atttaaacct acaaaaaaat acagtatagt tgaatataat ataggagata
    46501 cttgtacaaa aaaagctttg tccaatactc ttcctactga ctgtaaaaat atgtacaaaa
    46561 acattaatct acatggtaaa ttgttaaaaa ttacagagac attctttaca aaggagctta
    46621 ctttttttaa tataaacact ccaccaatca taattattat tcctgcaact tttgctaaac
    46681 ttaaaccttc acctaaaaat ataactgata aaagtagtaa aaacaatgaa tttaaactgt
    46741 ttattggagt aacaagtgaa acttctccag ttgctaaaga tgtcacatat gctactgagc
    46801 caattgaata tactaaacta cttatataac atggtattaa aaaagaccaa tcacttactt
    46861 tatccattat actaaatggc agtaaacata ctcctcctat aaagaaaaat aaaaatgatg
    46921 aagctatatt tttataaata tctccttctt catcacccaa taatcttaca actactcttt
    46981 caaaagctaa aagcactact ctaattaata atgcaaaata agataatatc atttttgacc
    47041 tcgcttaaaa attaatctga cttattgtta tattgattgt acaaaactac catataggta
    47101 aatcttttgg attttttaat attttatgct taaatacagg tatattaagt ttttcaccta
    47161 acttacggca ttgctcctta taagtacctt ttaacttatc atgaaaaact atgccatcaa
    47221 tcccatctgc aatactattt atacactttt ctagtttctc aagtcccgat tcatcatcat
    47281 acattccact tacaatccat tgatttggca atacatgccc aattgatatg ttaaattctt
    47341 tattttttat aatatctgag aaagatttct caaaatgtac ccctccaaca cataataaag
    47401 tcttcaaatg ttcatcacaa tcaaatactc taattaatga ttttgccaat acctgtattg
    47461 ctatactatt attaaaacta tcactactac ttcctatctc aatgtccaac ataggtacag
    47521 aatattctgt aattaattta gattctccac catatgttgt tccagaccag tgggttgctt
    47581 ctgttaatgt agtaaattca tcaagtgaat tttcattttt tatatcttca atagcattaa
    47641 ttaggttttt aaagtatctt ggatttgaat tgccaaattc tcctgttgga acatctccaa
    47701 ttgtatgagc tgttaggata tgttctggag cattttctcc ctcatgccaa tttacaactc
    47761 ctgcaaaatc ataatctctg aaatgtctat ttaaaattgg aagataatat tcataatcat
    47821 gacttattac atattttgtt tttacaaaat gaaataagtt attgttttta tctttaaact
    47881 ctaatacaaa attatcatca ataacaatat cagtttgatt taaatccatt atttcctcac
    47941 aacactttat tacattacta gctactgggt ctttctttaa atcactacaa aagaaaaaaa
    48001 ctgctttttt attattcatc cataaatcac actcctataa cttaaatata atctgttctc
    48061 atacttaaaa ttatttaaat atcactctag ctccattaaa ttatttatac ataatatact
    48121 accatactca ttttagctat gcctttgcct gagtttctat atatatgtga tacatcagct
    48181 ttaaatctta tagaatttcc actagataca acataatctt ctccatttat tttaatggtt
    48241 acctcaccac taaaaacagt tataaactct tgtgttcctg gaagttcagc atttgaatct
    48301 aaatttccac cctcctctat ttcaatcata aatatctcaa accttctttt cgaatcaaat
    48361 ggaaatattg gatagcttat atattttcca tcatcttcaa taaaatggtc tacatcactt
    48421 ttttgaatca attctatatc actttcctgt ctctccatca atgatgtaaa tgagattttt
    48481 agtccattag ttattttctt caaagtagat atggtaggat ttacctcaca cttttcaatt
    48541 tgagacagca tactcttact tacaccacta agttgtgcaa tcttatctaa gctaagatgt
    48601 ttttctttcc ttatcttttt taagttctca gcaattattt catttaaact ttgcataaat
    48661 tcctcctaat atgcttaata aaaacaagtt attttgatta tttaatagat ttagtaactt
    48721 aatacaattt ttatccatta taatgtacat tatgtttaat atacattact tctttaagaa
    48781 tgtaaatagt tttctgaaat tttgtaaaag tggacaaata aaaagctagc aacctatatt
    48841 tttacaaggc tactagcttt tattatcata atatttcatt ttaactataa aacttagatg
    48901 cacctataag ctgtctctta gaaacaatct tagctaagtt tgctaatgaa gaaattttta
    48961 tatctttaaa agaaactaaa aatacaaact taaaatctgt aaattcttga tttatattgt
    49021 atatatcaaa ataacatctc aaattatcaa ataagtaatt atcttgtaaa tctgcttcta
    49081 tctcatcagt agcatctttt aaatacgctc ttacgtcttc aaataaaaca ctgaaataag
    49141 attcatctat ttcttcacct aattcttcta atatttcttc tatatctaaa tcgttcatat
    49201 caaaagaatt tcctgtcaac tgacaatcaa atactaatat attttcttga tttatagtat
    49261 ttgatatatc ttgtacatat tcaaaatctg gacgtaattc taaaatgtct tttatttcac
    49321 tactctttac atggattttt ccttttctat tttcaatttt taaatctatc atatgctccc
    49381 cctttcaatc tacaaatctt taaatacctt gttttataat cttttcaatg tctatccaat
    49441 tattaactct aactatattt tgatgtttaa catctttatt atagttagta tccagaagta
    49501 ttactttaac accatcatca gctagttgca ctgagtttaa agggttatct tctataaata
    49561 tgtcacaact cagctctctc gccttttcaa ctttataatc acttcctaat aagtaaacat
    49621 ctatatctga aaatccttgt ctcgataacc aatttttagt tacatcagtt aaacactcat
    49681 gtctagctgt tacaaaagat aaattatgtc ctttagataa tgtgctaatt acctctgtag
    49741 caccctctac aatctttgct tcatcatatg aatgtatata cttattatta aactctgcat
    49801 atacatccct tattcccgaa ccatacaatt cttcccaatt atgtgttata cactctgctt
    49861 cagtgatatt tttattaaaa atatcattta ggtatggaag aaaatgataa gggcttgtta
    49921 ttgtcccatc tatatcaata catatattca atttgttcat ttttacctcc atgtaacatt
    49981 tattgatttg attaatcaaa cattatagca cagctttaat tataaatcaa aactctagat
    50041 atgactatac ctatataata ccaaaaagcc tgcatattta agcaagcttt tcgtaaattt
    50101 tacattttta actaatatat aagtttttct aaggttggtt ctactccaaa ttgtgatttc
    50161 agttctttat attcttttaa tgctttatca ttatttgttc tagattttat agctcttatc
    50221 attaaatttt ttggtgtgtc aagtggagat atgtattcta ctacagaagt atcatatcca
    50281 ttgccctcca ataacaatgt tcttaaacca tcagttatta agtctgcaaa tctagcttta
    50341 aatacaccat gttttaatat tggttccata gcttcatatc tatattgacc caataactcc
    50401 ttatgacaac atggcactac tactatagct tcagattttg ctctaattcc taaacctatt
    50461 gccatatctg tagctgtatc gcaagcatgt agacttatta caaggtcaac atccctatta
    50521 ggtgtataat tagtcaaatc ctcttttata aatgacatat ttttataacc taaattttta
    50581 gccatatttc ttgatgcttc tataactaca tctgaataat ctatacctat aaaataacaa
    50641 tttttcttca atacctcttt tatataaaag tttaagacaa agcttaaata agattttcca
    50701 caagcacaat ccaagatagt tatacagtcc ttatccttta tttcttttaa gatattatct
    50761 atcaattcaa caaaatggtc tatctgattg tattttctta ttttatcatt ttttatctta
    50821 ccatcttttg taagcactcc aatttctttt aaaagtgcat ttgcctgtcc tacttttaca
    50881 taataatctc tgttttttat ttgagatgct gtaaattcat ctattttagg tacttcttcc
    50941 ttattatcta aatattttac atttaccttc ttattgtctc cttcaattaa aacaatagtt
    51001 cctcgctcaa catatttaaa cactaatcca tcataatttt ctgcctcttt agaaatattc
    51061 ttaagcaatt cattaaatgt atataaatct gattttcctt taaaattaaa tttatattta
    51121 ttatcttcct ctattgcaat tcctttaaac tcttttcttc cagatttaaa aattacctct
    51181 aactcaataa aaaaatccct gttatcaaga tttctttgag taatccccat aaaaaacata
    51241 tttagttttc ctatactctg cttattcatt gtaatctccc ttttaactta tatccttaaa
    51301 tcttattaat tgatactatt tgtttctgtg ttatttattt cttcttttaa atcattcaat
    51361 ctatttttaa aactttctat ctgcttatct gataaatcaa gatattctgt tatcttccct
    51421 atatacttag ggcttttagt atttattaat ttcaaagcac tttccataga tttttctcta
    51481 agttcatatg ctttctttac atcatctcta gcattactca atgtttctgt atacttctcc
    51541 ttagaaagtt ctggaatctg catattttca tattctttta caacttcttt acacttattt
    51601 cttgcatttg taacatcttt ttttatacta gataatttag ttatattttt tgcgatatcc
    51661 ttagtgtaag gtatacattc tctcattgga actaaagctg ctctttctat attataaatt
    51721 tctttcttaa aaattcctat actttccata tctatttttt ttatatcttc actatttttt
    51781 tctttacttg tatatttatt attttctttt gtagtatctt cttgtttctc tgatttatta
    51841 ttcactgaaa cattactatc agagttattc ttttctttta tgttattact tccttcttcg
    51901 ttgctttctt tattttgtat atttttattt tgtttgttgt ttaaattttt attatttgat
    51961 atctcttcat tctttttctt atcctgtttt aaatcagtac tttctttttc cttaaagttt
    52021 gatacatact tttcgtcata tgtctcatca gaaatataat tgtgataata catagattct
    52081 tttattttat taagtccact catataaata ttacttatca ttattgttgt agccaatact
    52141 acataaatac tactatagat acaagacctc ttaaaattct tgtaatttct gaatatcact
    52201 actaaaggaa taagatataa aaatataaaa actaatatcc acctcataag tcgtgtctcc
    52261 tttctcaaaa ccgaaatccc tcaaatattt atttttaatc atgtatctta tagtatttac
    52321 caatttatgt tttttaatcg tgaactttta ttaaattaaa ttctgtatag tcacaagatg
    52381 ctaatgtata ttctactcca tttcgaatcc ctttcaatcc cattttaaaa gattctttac
    52441 catgcaagtg accataaatc accttttcaa cattatattc ttcaaataac tttgtaaata
    52501 aagattcttc taatttatca tttgtaggag gataatgagt aatcacaatt atttttgagt
    52561 gaccactttt acgagcagat tctaatgata acctaagtct atgttcttct cttttataaa
    52621 ctttttcatc agtctcatca aacttaacat cattaggaca tatccagccc ctacctccac
    52681 aaattgcata atctttatat tcataaaaat ttgtctgaat aaaacgcata ttttcatata
    52741 acttatttaa acttgtaacg gttgtccacc agtaatcatg atttcctttt ataagtattt
    52801 tctgacctgg aagtttgctt attatatcta aatctttttt agcttctgat aaattaattc
    52861 cccaagatgt gtctcctaat actaagacca tatcttcttc cttaacaact tctttccaat
    52921 tatctataat cttcttttca tgaccatccc aattacttcc aaagatattc attggtttat
    52981 tgactgatgt tgaaaaatgt aaatcaccta tagcatacaa actcataata tcattccttt
    53041 cttgattaca ataaataggc tgtctctttt tagaaattat tttccattaa gaggcagccc
    53101 cattaatatt tagcaacttt tctacaagta gtttttactg aactacttta tcatctacct
    53161 tagtatcctt atattgctct agtaatatat ctatttcttg ttttaattcc aaaatttcag
    53221 ttatattttt atctgtttca gttctatcaa gttttctttg atactgcata gctttatgtg
    53281 tatcacccaa gtcatataac tcttgtattc tatttagagt atctctaata gctatagact
    53341 tcatttggta catagcctga gctttcatta tatcttctct tatttcactc atttcttggt
    53401 ctaaaagaaa ggcagcatca gatgctcttc taagtctttc agcaagagtc tcaggtatgt
    53461 aatggtcata tttatatttt aatgaatgtt ctattgtagc ccagaaattc attgcaagag
    53521 ttcttatttg tatttcacat ataatttcct ttgaacctgc aatggagttt atagggtatt
    53581 ttattataac atgatagctt ctataaccac tatctttgta atttgtaata taatcttttt
    53641 ctcctattat agtcatatca tttcttactt ttatcaaatc aactatagca tatatatcct
    53701 caacaaactg gcacattatt cttataccag caatatcatc aatttcagtt tctatatctt
    53761 ttgcatttat cctttttaac ttagatatta tggaagatat tttttttgtt ctgcctgtga
    53821 caaactctat gggagaatat tcaccttttg ctaaatattc ttttcttata tttttaaatt
    53881 ttattttcaa ttcctctact gcatgttcat aaggtgctag tatctcattc catttttcgt
    53941 attccatatt gctcaccctt tatttgtttt ttatgacctt ctttatttta tcataattta
    54001 ttttgttttt gtatagtaaa gcaattctcc attttccaat atatacccta tttcttctaa
    54061 atcaactaag taacttatga cagatactaa cgaagattta aaaaaatgat actctttata
    54121 attattgctt aaattattgt tatttataat gttttttaat aaaatttcta aagatttcgg
    54181 ttctacaagc aactctctta tttgatgtaa atattttttt aaagcattca aatgtttttc
    54241 gattaattta taagaatctt cttttgatat aacttgcttg ccatgaccta aaactaagta
    54301 ttcaaaatct atatttttta atttttctaa tgaatttatt tgttcttgta tatcatatag
    54361 aaacaagaag tcgtattttg aaagaatttc atcccctatc aataaatcgc caacaaaaat
    54421 cacattatcc ttcgtcaaaa cagctatact accaggtgta tgcccctgaa actcaattat
    54481 atcaaatatt tcattattta attcaatttt tccagctttt atagatttat ctatctttat
    54541 atcatccaac attttatttt ttaagatatt atccataaat acattgctct ttccaccaac
    54601 aatatacttt gaaaataatt ctggattttc tatatataac ttatcgtatt cagatgacat
    54661 tatacgcaca tctttatagt actctttaaa ttgattacaa gctccataat ggtcatcatg
    54721 accatgagta tttataatat atctaacttg tatattattt tcatctaaca ctttatttac
    54781 tctcctaggt cttgaaccac ataaccctgg gtctatcata agtgctgtgt tatcttcaaa
    54841 tatatatatg cctgtatttg tgccaccttt tataaaaaag gtatttcctt ttacttttgt
    54901 aagattcacc ttcttcacct cattttgaca atatttatga tacaatttat tacttgctaa
    54961 tataaaacta tacaagaata atccttttta ttctatctat agttcttttt cttatttcgg
    55021 gttctttaga tatccttatt ttcacattat atgctaaatt tctataaagt aatgactcta
    55081 taaaatattc aactatacct ctatccctaa agtctatatc tatacatcca cttgaataaa
    55141 tatttgagtc taatgtcata agctcatcaa aaaagcttaa tctcttagat ttacttaaat
    55201 aatctttatt tggaataaat ctatcacaat aatctatcct gtaatttact acttcatcat
    55261 ttatttcaaa tccatattgc tttttcatta actctctata gttattattt ttctcaataa
    55321 cattatctaa atttttatta taatcctctt ttttccaatg tccaaacatc ctacaattta
    55381 atggtctaac ttcatatatt aaacatctat tattattatc tttaaatgga catggattct
    55441 tttttgtata ctcctcaaaa taataatcta atattttact tatacagctt ttttttaaat
    55501 caactctatc ttcaagataa caaaatatat tcaaaaactc aattaaattt atacctactg
    55561 actccataca acaatttcca catcccaaac aatttcccac tggcaaggat ttatatacat
    55621 catttagttt ctcaaagagc ttatttttaa tggaataatc tatacaattt aaaatatctt
    55681 tattttttat actagtcatt attattactc cttgttataa ttattaagtt aatacaaaca
    55741 attattataa catatttttt aaatttaatc gcatatggag gtattttatg aatagatata
    55801 caaaaataat taacatgatg ggaagttatt acacaaaaga ctttgaaaaa gaaaaaaaga
    55861 acgtaataaa agttagagaa gttaaagaag atacagttag aaaatttttc ttacaaggtg
    55921 actgtgaggt tcttgtagta tttgaggata ctggaaaaga aatacttatt gatgactttt
    55981 ctcctgaaga agatatcaaa aaatatttag gagcaaaatt cataaataaa aaaagataat
    56041 tatcaaaaat aattctaaaa ttaaaagtta ataaatataa agttataatt ctatataatt
    56101 atagttaaaa gttatctttt attgcttttt tagactttaa gatagctttt tttctatttt
    56161 ttgtaaaata gttccataat tcacattaat aattcacaaa atgatataat ataacaaata
    56221 gataaatttt taaatttcta aatacataat taatattttg cgaggtgatt ttatgcaaat
    56281 ttattttaga gttaaggcta ttggcaaacg taaacctatg ctaaaacttg ccccttttga
    56341 tgtatctgac aacatcaact gcctaaaaga agctatctct gaaattgtat ctaaaaatgt
    56401 tcttgaatat aatgagaaaa tcccagaaaa atcaatagta aacttcttaa ctaatgaaga
    56461 aattgaatct caagctaata ttggaagagt tggatttggc tctatttaca atgagaataa
    56521 acaatctgta gaaaaggcaa tagaagtagc gttacaagca tttgaagatg gaatctacaa
    56581 agtgcttata aatgaagatg ttattgaaaa acttgattct cctataaatc tgaaaagtgg
    56641 agatatattt acttttataa gacttacctt gcttgctgga agaatgtttt aaaataaata
    56701 acttggaggt acataaatgt tagaacgtac tagagtagaa aaaaatccta aaataattga
    56761 aaatttaaaa aacaatttta ctaaatcttc ttcaaaacag tattacgact tagcaaaatc
    56821 tctttgggac tgcatagaaa atagttcata ctattataga gaacctgaag acaaattctt
    56881 aaatatgata aagaaatact acaattgcca ctactacgaa attaaaaata tggacgagct
    56941 cctttctgga cctttaaaaa atgcattaga attaatattt acttctgaac aagtagagga
    57001 actttgccaa ttaattaaaa gaaagatgga ttatacatat tcaggaggat attatcgtaa
    57061 aggatatcgc tcaaataaac ttgtggatta ttttagaggc attataaggt ttatttccag
    57121 ttatgttgat ttgatttatt atgatttttc agttatagat tatcttactc ttccaaataa
    57181 agtcttgtac tatgactcta taatgagtga taaaatagca ctagaaatag acaaaggaaa
    57241 tcaagaagta ataagtgcct tagaagaagt aatatttgga gaaaatcaaa ctgctctact
    57301 tacaagacaa atgataattg gtatcatgaa gagtcatagt gataaatgct atgaaatgat
    57361 ttctaaactt cttttggcag ctaaacaaca agagggactt agacagcaaa ttgtagaaag
    57421 tttagatgag ggtacaattt ctgcatcaat atacatgtta aaaactattt tggacaataa
    57481 tttagagcga tttagttctg ttataagagc cttggataca tggacaggac ttggtttttc
    57541 agaccaaaaa cctggaataa tacgtaaatg tttagaactt tcatataaat cattgactga
    57601 tgaaaagttc cgtatagaat caattaatag caatgataat cttgaagttt attttgcctt
    57661 atgggctact gcaacttaca acatatatga ctcttactct cttattgaaa acttactttc
    57721 ttgtcaggaa aaatataaaa aacttgtagc tctttacttt ttatcgcata cagaaagtac
    57781 atattttaaa cattctatag catctaaaaa cattaagggt gatgatttag agatactagc
    57841 atgggtaatt acaaatttct atgtagaagg ttctgttggc tactactata gttggcaaaa
    57901 cagagaaact agttttgacc tgtcaaacac tcctattgac aaagacttta atgctagaaa
    57961 agaacaattt gaaagtttaa agcatacttt agaaaattta aattcaaaga caaaatcatt
    58021 ttcaggaagt gtatttccat ggacttggat tgaaatttct tctcatgaaa tacttaagtg
    58081 tatgatgact ttaacagcat acgatatgaa tgctcaattt atagatgttc ttatggaaaa
    58141 ttgtcatctt atgagttcag atttaagagc ttcacttata gtaaattttg taaatgaacc
    58201 aaagacagat agacaacgtg aatttttatt ggaatgttta agtgataaga gtgtttcaaa
    58261 tagagaaata gtattgactc tacttagaaa acttgaacta acagacatgg agttggataa
    58321 gataaccaat ctattatctt taaagacaag ctctattaga caaacagtaa taaaaatttt
    58381 acttgaacaa gatgattcaa aattggagaa tattgcttct tcactgataa aatcttcaaa
    58441 ttctcaaaaa tgccttggag gtcttgaaat tgtaaactta ttaaaagaca atactgatag
    58501 aaaagaacta tataaaaagc ttattttact gataaaagat attgataaat ctaaaaagaa
    58561 tacatctcaa gttcaaatac taattgataa tttactaggt aaagcaaaaa atgattattg
    58621 caaagaaaat ggttttggaa tatataaccc agaaaataag gttcaaattc cagaacaatt
    58681 tgattttaaa gataattctc ctagtttatc aaaacttgat aaaattattt caaatacaag
    58741 tttatctact aatgaggatt ctgtttctgt agcaacaaaa aaagaagcaa aaaaaattct
    58801 cgatacagat ataaataaaa taataaaagt ttatgaaaaa tttgatgagc ttattactga
    58861 aaatgcagat tatgaatatg aagttgaaag atggtcaggt aatgtagaca aagtactttt
    58921 aggctattct acttataatt tgactcctat taaatataaa gtttctaatg atactctaga
    58981 taattatcca ttggcagaac tttggagaga aactagtaaa aaacttaact tagactacaa
    59041 attaatactt gatatattat tttatagtat aagtacatgc ggatataatg aaatagaaaa
    59101 aagttggttt tcatctatat attcaaatgt ccttgactct aaaaaacaaa ataaaatatc
    59161 tacaaaactt gaaaaattaa aattcaatgg acttacaaga aagcttctaa gagttttact
    59221 aaatgagttc gaccataaag aaatatttaa ctattgtttg gaagtatact ataaacttag
    59281 aaacttatta actatagaac aatgtaaaaa gcaaagagtt gagtttacta aaaattatta
    59341 tagacaaaat gaatactgcc ctgctttaaa tgcccctatt ttaaattatt ggcttgataa
    59401 agcacattca tttatttatg atgatatttc ttttactaag tttttctaca ctacattttc
    59461 aaattatcag ttgctagaat ataaatttcc tttttatact agcataaatg tatttgctcg
    59521 tgcacatgaa ttaggattaa tgactaaaga gcaagttaat agagaaatga taagtggata
    59581 caacgcaaca aatataataa gaacgttaac aaatcctaga tgggctggtg acacattaga
    59641 aaaatatcct tggcttaaag ataacttaaa aaccgttaca aaccgaatta tagaaattga
    59701 atcacgtaga ggtgatatgc caacagaagt gtctcatcta gctaataata tacaatactt
    59761 tgaaggtata aattattttg taaatatctt agttgctctt ggtaaagaaa ctttccagag
    59821 aggatattca tatggtagca attattcaaa aaaagatgtt ttaagttctc tacttaaaaa
    59881 ttgctatcct acaaaagaag atgattcaaa aaaattaaaa agtttactta aaaataccga
    59941 cattactgag ttaagattga tagaatctgc tatgtatgca cctcaatggg taaacataat
    60001 tgaaaaatat ttaaactgga agggtctgaa aagtacaatt tggtacttcc acgcacatat
    60061 aaatgaagga ttctctgcac aaaaagaatc agaggttgct ctattctctc ctatatcacc
    60121 acagagtttc atggatggag catttgatgt agattggttt ttagattcat ataaaactat
    60181 tggggaagaa agattcaata tactttacaa atcagctaaa tatataacta gtggcggaaa
    60241 ttctcataga cgagcacaac tctatgctga tgctacactt ggaaaacttg ataaagatat
    60301 gctgatgaaa gaaattgaaa caaatagaaa tcaagataaa ttgagaagtt tctctttact
    60361 tcctatgaaa aaaggagacc ttaaagaagc aactttccgt tatgaattta ttcaaaagtt
    60421 tgccaaagaa agcaaacaat ttggtgctca acgtcgtgaa agcgaatcaa aagcttgtgc
    60481 aatagcaatg gaaaacttag ctagaagtgc tggttttgaa gatattaatc gtatgatgtg
    60541 ggctcttgaa acagaaaaat taaatgaagt tgcttatata ttcaaaccaa aaaatattga
    60601 tagaacttca ctttggatag atgttgatga aaaaggaaaa acatctataa aggttcaaaa
    60661 aggtgataag gctttaaaaa gtgtaccaaa agctattgct aaacatccat atgtacttga
    60721 acttaaatct gttcaaaaag atttaaagag tcagtattct cgtgcaaaac agagtttaga
    60781 gcaagctatg aaaaatgaaa tagtatttac agttaaagaa attgccaata tctataaaaa
    60841 tccagttatc tgccctttga ttaaaaatct agtatgggta tgtgatgata atattggata
    60901 tgtttataat gataagtcta agttctttat ttgcaatata gaaggtgaaa tttataagtt
    60961 gacagcgaaa aataaattaa aacttgcgca tccagttcat ttgtttgagt ctggtaagtg
    61021 gagtgagttc caacatgatt tatttagtaa gcaaattgtt caaccattta agcaagtatt
    61081 ccgtgaatat tatagaataa acagtgatga attatctgaa aaaactatat ctcgtagata
    61141 cgctggtcac caagtccagc caaagaaaac tgtagcactt cttagaaatc agctttggac
    61201 tgtcgattat gaagagggat tacagaaagt attttataaa gaaaatatag tggcaaagat
    61261 gtttgcactt gcagattggt tttcaccagc agatatagag cctcctacta ttgaaacagt
    61321 agaatttttt gatagaaaaa cttataaaag cttggaattg gcttctatac ctccaattat
    61381 attctcagaa gttatgcgtg atatagacct tgttgtaagt gtcgctcatg ctggtggtgt
    61441 tgaccctgaa actagccatt ctactgtaga gatgcgtata gcaattgcta aagaactttt
    61501 attattatta aaagttaaca atgtcaattt tgaaggctct catgctctta ttgaaggtac
    61561 tttaggtgag tattctgtgc atatgggttc tggtattgta cataaaaaag gaataggtgc
    61621 tttgaatata cttcctgtac attctcaaag tagaggtaag atattccttc cattcgctga
    61681 tgaagatcct aaaactgctg agattatgtc taagatacta ttacttgctg aagatagtaa
    61741 gattaaagac cctagtatct taagtaattt ataagtataa aaactatccc taaaatatat
    61801 tggactttct taaaaaaatt agaaagtcca atatatacta tactgtaatt tatataaatt
    61861 aaatcataat tacaaataat ttttatatac acttctctta tacattatct ttatggtact
    61921 tattatgtca cacaaaaagt atttttcttc tattttcact agaatctttt aaccctataa
    61981 aatctatata aaaagtcttt ttctagagat ttgtttaata tggcattttc ttgaaaattt
    62041 ataaacctta tctctaatga agatttattt ataggtataa ccttatgtat aaatcttaga
    62101 tttacaaggt atataaaaag ttataaagct agatctttag cgattgctgt gagtataatt
    62161 cttgctacat cactcgttgt tggtattggt actctatcaa gaagtgctca gcaagcagat
    62221 gtagatagat tgaaaagaga gcttggaact gaccatgtat actttaaaaa tataaagaaa
    62281 aatcaattaa agtccataaa atctagcaaa gatattaaaa atctgggtat aacatcttac
    62341 tatacgtcta cagatgttaa tgaaaaatta cctataaaca tactatatgc aaataaaaat
    62401 tatttgacta gtcattctaa acttataaaa ggtcgatttc caaaagctag caatgaggtg
    62461 gtagtcgaga aatggatttt aaatagtatg ggcttaaaac cagagataaa tcaaaacctt
    62521 acttttaaat tatatcaaaa agaaaatcca gaaactttta aagttgttgg aatccttgaa
    62581 gatagattta tagagaaaca aaagggacaa tgtgaaattt tttctaatct caatgaatca
    62641 aaactgaatg attttacaac ttatattgaa tttaatgaag gcagtgatat aaatacaaac
    62701 atagacaata taataaaaaa tgctatgtta gatgagaaaa gtataggaag aaactcaatg
    62761 cttatagaat ctactatgaa aaacggtact ttagataatg caagtaaata cgttgcaatt
    62821 gctatgagtc tatttgctgg tattgtaata tatagtatct atgttatatc aatataccaa
    62881 agagtacagg aatatggtgt cttaagagct attggttcca ctaactttag gattttcaaa
    62941 cttatgcttt atgaactttt catacttgct ctaatagcaa tgcctatagg tatatgtata
    63001 ggtatggggg gtgcacaaat atttaatagg tctgtaggaa atattcaatt tgaaggaaat
    63061 ataaatgtta caccttttgt tattccagat aaaataatcc tcttatcaat tgcatgtaca
    63121 atactaataa tactaattat aagtttcttt acatacttaa aaataagaag aatttctcct
    63181 attgatgcta tcagaaaaac ttttggtgct gataaaaatg taaccacagt taattattta
    63241 atatcaaaat taactttaaa tatgtcagta acaaaatcta tatctgcgaa aaacatcttt
    63301 agaaataaaa aggggttcat tataattgta ttatctatga gtataggagg tataatcgtc
    63361 ataaaagaca attataaata ttctttttta gatgtgcaaa acaaatccac tcaagagcaa
    63421 acatatatga atgcagattt tattctatca aatgtttatc tcaatgaaat tggtagcaat
    63481 acttctttta aagatataaa agggtttagt gatagtcaga tagataaaat aaaaaatata
    63541 gatggaattg acaaagtcaa aactgctagt atcttaaaca caagaataga ggtaaataaa
    63601 ataaatagat tagattacta cgaagctata aattcaaatc cttattataa actaaatcct
    63661 ctgttcataa aaaataagac tactggcaaa tatacactaa agcaaaaact aaaaggttat
    63721 aatgatgaga tgataaagtc attagaaaaa tacttagtaa gtggaaatat aaacttgaaa
    63781 gaaatgaaaa aagaaaattt agctattgta tatgtaccag aaatttctaa aacacagaaa
    63841 tacacaaaga cttttactcc tggtgaagga acaccagcta tagatataaa agtaggtgat
    63901 actataaaag tcaaatatcc aaagggtgga atggatacag gactttatga aagtctaaaa
    63961 gataattatg aatacttaga atatgaattt agagttggag ctattataag ttatactttt
    64021 gcagataatg gtatgtactc tggagatgac ggtgtagatg taataacgag tagcgaatat
    64081 ctaaaaaaat taactggtgt agataagtat aacttagttt atgcagacct taatgaaaat
    64141 gcaaacaaga aaaaaataaa taacctttta ggtaaaattg gaagtgaagt ttctggaact
    64201 acaacagtag atatgatggt agaaaaagaa aattctgata agatgacatc tagaactatg
    64261 atttatagtt atggcatagt agcaataatg ttcataatca gtgtacttaa cataataaac
    64321 aacataagtt ataacttaac ttcaagaact agtgaatttg gaatgttaag agctattggt
    64381 atctctgaga gaggatttaa aaatatgata ctttatgaag gaatattata tggtgtactc
    64441 tcaagtataa ttactattgt gtcaggactt ataatacaat ttaaaatgta ttacacgcag
    64501 ggctttgtat catatggatt aggattttca atagattaca aaatatacat actagttgtt
    64561 gtagcaaata taattgtagg tattctagct acatatattc catcaaggaa gataaataaa
    64621 attagtatag ttgaagctat aaacattaca gaataggagg gataattatg cctatattgg
    64681 aaactattaa tttaggtaag atttatggaa aaaaggaaac atctgtacat gcactaaaga
    64741 atgcaaattt aaaaataaat aaaggcgaat ttgttgctat aattggacca agtggaagtg
    64801 ggaaaagtac atttctacat ttagtaggtg gtcttgagag accaagtaat ggtactataa
    64861 aagttgctgg taaagatata tgttgtcttt cagataaaga actagcaaga tatagaagac
    64921 aaaaagtagg atttgtcttt caacaatata acctaattcc tgtattaaat gtaaaggaaa
    64981 atatagaatt accattaaag ttagacaata aaaaaataga taaagaatat attgaagacc
    65041 ttataaattt attggggctt aatgaaagga aaaatcatct tcccaaccaa ttatctggtg
    65101 gtcaacagca aagagttgct attgcacgtg ctttatctgc aaaaccaagt ataatcctag
    65161 cagatgaacc aacaggaaat ttggacagta aaactacaga agaagtcatg gatttactaa
    65221 aaagttctat aaaaaaatat aaccaaacac ttataataat aacacataat gaaaatattg
    65281 ctagaaaagt agataaaatt atatctataa tagatggaga gcttaaatta acactctaaa
    65341 actatttata gaaaagagga tttaaatgtt attgatttta ggtaatttaa atttaaactt
    65401 ggattttgac tacagaataa taagagaaga aaatgatgat gtagatatat tcatagatat
    65461 taattatcgt agcttagata tagatactga tggttctaac ttatttaatt ctagaataca
    65521 atttccattt gtaagagcat taattctaag gctaaataag aacaatcaat gtatgacaat
    65581 tcatttgtta agagatatag atttattctc tgcttttgcc aactttgaag tggattatac
    65641 tgactctata ataaatataa aaaatcaaaa tgagaaagta attttaaata aatctatcaa
    65701 aaaatagtaa gggggcctta ataggcccca atttttttct tttctaaatt tattatatca
    65761 tgataaataa attagtcaat agaattttct gaatattttt ataatttttt cataaagttt
    65821 tttatatatt atgctttaaa attatatgta atagaaaatt tttccgacta attttaaagt
    65881 tactttatta aatacacata ttcaaaattg acattaaatt attgactttt tatcatttca
    65941 atttagaatt taagttatta tttataacta tttatacgta tctctaataa aactctattt
    66001 atattcaagt ccaataattt atatacaaaa ccaatagaac ctatgttgta caatgaatat
    66061 tatttaccat aataaacttt tagatatatc tcttttaatt cactcatcaa tgggtatcta
    66121 ggattagcac ctgtacattg gtcatcaaaa gcttgttcaa ccatagcatc cagtccttct
    66181 aagaatttag attcttctac tccagcctct tttatagtct taggaagacc tacttttgcc
    66241 tttagttcat ctattgcttt tataaggtta tctacttttt cttggtctgt atttccctta
    66301 attcctgcaa aagaagcaaa ttcagcatat ctttgtatac aatcaggata tctgtattgt
    66361 gagaatgcac ccatcttatt tggagcttct gcacaattaa acttgattac ttcatttatt
    66421 aataatgcat ttgcaacacc gtgttgaaca tgatggaatg cacctaattt atgtgctaaa
    66481 gagtgacata ttcctaagaa agcatttgca aaagacattc ctgccatagt agatgccatt
    66541 gccatttttt ctcttgcttc tttatcattc tttccatttt tatatgcacg aggtaaatat
    66601 tcaaatatta ttttacctgc ttgtagagct aaaccgtcag ctggttcagt tcttaacata
    66661 gatacatatg cttctagtgc atgtgttaaa gcatcaacac ctgatgacgc tgttagtctt
    66721 ggtggcatct ccatcatcat atcagcatca attatagcca tgtttggcat taattcataa
    66781 tctgctaatg ggtattttac gcctgaatct tggtcagtta taactgcaaa tggagttacc
    66841 tctgaaccag ttcctgctga agttgggata gcagcaaagt atgctttttc acccatctta
    66901 gggaatacat atactctttt tcttatatcc ataaatctca tagctaagtc ttggaaatct
    66961 acttctggat gctcatacat tacccacatt atcttaccag catccattgc gctacctcca
    67021 cctacagcta ttattaaatc tggttggaaa tcagccatag ctttagctcc ttctcttgca
    67081 caagctaatg ttgggtctgg agctacatca aagaatgtag tgtgcttaat tcccatctca
    67141 tctaataaat cagttaactt cttagtatat ccattattat ataggaaaga gtctgttact
    67201 ataaatgctt tctttttatc cataacatcc ttaaattctc ttgctgctac acctaaacat
    67261 ccttttttga aataaacttt ttctggtgct ctgaaccaaa gcatattctc tctcctttca
    67321 gctactgtct tgatattaag caaatgtttc actcctacgt tttcagatac tgagtttcca
    67381 ccccaagaac cacaaccaag agtaagagat ggtgccaatt taaagttata taaatcacct
    67441 ataccacctt gtgatgatgg agtattaact aatactctac aagtcttcat agcatttaca
    67501 aacttttcta ctctctctgg atgatttata gagtctgcat ataatgaaga tgtatgacca
    67561 tatcctccat ctgcaactaa tttttctgct ttggcaactg catcttcaaa acttttagac
    67621 ttgtacattg caagtacagg agaaagtttt tcatgtgcaa aaggttcatt taattcaaca
    67681 gattctactt caccaattat tattctagct gtttttggaa cttctacatc tgccatttta
    67741 gctattatat gtgctggttg tccaactatt ttagcattta atgaaccatc aattattact
    67801 acttttccta ctttttccgt ttcttcttta tttaagaaat gtgcaccacg atatttaaat
    67861 tcttttttaa cttcttcata tattttttct ggcacaatta ctgcttgctc tgaagcacat
    67921 atcataccat tgtcgaatga ttttgatact aatattgaac ttacagccat ttttatatct
    67981 gcactctcat ctattattgc agggacattt ccaggtccaa ctccaacagc tggcttacct
    68041 gaggaatatg cagatttaac cattccaggt ccaccagtag ctaatataag gtctgcctct
    68101 gccatgacaa cattagttaa ttcaatcgaa ggaacatcta cccaacctat aagacccttt
    68161 ggtgcgcctg ccttaactgc tgcatcatgt acaactctag ctgcttctat agtacagttt
    68221 ttagctcttg gatgaggaga gaaaattata ccatttctag tttttagtgc tattagggat
    68281 ttgaatattg cagttgatgt aggattagtt gtagggataa ctgctgataa aacacctact
    68341 ggttcagcaa ttcttgtaaa accaaatgct tcatcttttt ctattacacc acaagtttta
    68401 gtgtctttat aagcattata gatatactct gaagcaaaat ggttttttat aaccttatct
    68461 tcaacaatac ccataccagt ctcttccact gccatttttg ctaaaggtat tctttgttga
    68521 ttagctgcag ttgaggcagc taagaaaatt ttatctacct gttcttgcgt aaatgttgca
    68581 aattcttttt gtgctaatct aatttcttct aatctcattc ttaatgtttc aacactgttg
    68641 acaatttcag gactacatac ttcaacactt gatttttcta ctacattttc ttttttctcc
    68701 atactacaaa cctccctaaa ataattatac atctacaatt tttataaatc ttaaatacat
    68761 catctgtact tttaacttat acttaaaata attttataga tttcatctct ataccttaga
    68821 ttttatttac tttactttct taggtcaaga agtttttttc tgaatatttt gtcaatttat
    68881 tttttaacaa atatattact ttttttactt ttactaaatt tttttatcta aatgagatat
    68941 atttcatttg aataatttac tttgactaaa taaaatacta aaatgataat ttatatcttt
    69001 catttttttt acttattaaa ttttatatgt tatttgtaca agcagtaaat aaaatttttg
    69061 tcgtattttt ataaaataac acttattttt gacttgtgtg caatttttct ttttatagca
    69121 actgtatggt tttaaaaaat atacaaacta aaattattct aatttctata agttattttt
    69181 aagtcaatat acaataatta tacttttcat atggataaat aatttttata ttcatcccgt
    69241 taatttttta atgataa
//
LOCUS       DAMKOJ010000008        68966 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000008 DAMKOJ010000000
VERSION     DAMKOJ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 68966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.008"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..777)
                     /locus_tag="PC592_000627"
     CDS             complement(<1..777)
                     /locus_tag="PC592_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDF4054641.1"
                     /translation="MAQHAILRFEKHKGNPARPLEAHHERQKEQYASNPDIDTSRSKY
                     NFHIVKPEGRYYHFIQSRIEQAGCRTRKDSTRFVDTLITASPEFFKGKSPKEIQAFFQ
                     RAADFLIGRVGRENIVSAVVHMDEKTPHLHLTFVPLTKDNRLCAKEIIGNRANLTKWQ
                     DDFHAYMVEKYPDLERGESASKTGRKHIPTRIFKQAVSLSRQARAIEAALDGINPLNA
                     GKKKEEALSMLKKWFPQMENFSGQLKKYKVTINDLLAENEK"
     gene            complement(962..1357)
                     /locus_tag="PC592_000628"
     CDS             complement(962..1357)
                     /locus_tag="PC592_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF4054642.1"
                     /translation="MTNTIYIHQPEKAFSFTRLPNFLFEAPTFKPLSNEAKVLYAFIL
                     RRTELSRKNGWADDCGRIFLYYPICEVVDLLHCGRQKAVNTLRELQYAGLVEIQKQGC
                     GKPNRIFPKSYEAVPNTDFKKSRSGTPED"
     gene            complement(1469..1882)
                     /locus_tag="PC592_000629"
     CDS             complement(1469..1882)
                     /locus_tag="PC592_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDF4054643.1"
                     /translation="MRNNPYKDLPPLERRPDGSLYRMTPAQRKQAASLIRRECCCCED
                     GNCIVLDDGDTCTCPQTVSFSVCCKWFRWAVLPLDGTLEAEIFRDKDLKRCVVCGGVF
                     VPKSNRAKYCPGCAARVHRRQKTESERKRRSAVDS"
     gene            2197..2997
                     /locus_tag="PC592_000630"
     CDS             2197..2997
                     /locus_tag="PC592_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054644.1"
                     /translation="MALPGTPGQRISDLCNGNHITQKELAEKIGVSASQLSRIVSGET
                     RTVSSDILIGVAKEFKVSTDYILGLSTVSVRKSYDISELGLSEGAVRGLVTGAVDVQI
                     LNRLLEHRNFPKLIDLIRIYFQDTAAKGIMARNQLIEMATASLSDLMKEHPEHRAEAK
                     QDLQLLNAQKMGEHEAEIEKIKNVFLAILRDIKKDIDNGEQPGEAVTAAMFQAMRDTM
                     AEQKQNPLSIDDVTAMIAGQIGQLAPMDKETADLFQQLAKKMIEQAGK"
     gene            3023..3652
                     /locus_tag="PC592_000631"
     CDS             3023..3652
                     /locus_tag="PC592_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4054645.1"
                     /translation="MATKIFVHGSGHKATSWEKTISYMTNNEDIVCPNLSSILEGKEA
                     SYENLYSSFVKYCNEFDGQIHLCGLSLGGILALNFALDFPQKVKTLVLIGTPYKVPKV
                     AFSFQNIIFRFLPKSIFETMAFDKKNTFALGDTMKNLDFSDRVKNIKCPTLILCGKKD
                     SANMKSADYLSQSIRSAELKIIENTGHVVNEENPKALADILNEYYLKNS"
     gene            3858..4724
                     /locus_tag="PC592_000632"
     CDS             3858..4724
                     /locus_tag="PC592_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase AadE"
                     /protein_id="HDF4054646.1"
                     /translation="MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFD
                     ITFFVTDMDSFTSDDKWLDIFGERLILQKPEDMELFPAVEKGFSYLMLFTDDVKIDLT
                     LLPLELIDEYFTWDKLVKLLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHMNDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYVP
                     EELWERLMSTYNMDSYPHMWESFEQCMALFREVSSEVACQLDYQYPLYDEKISNYVIR
                     QKKKYGIEDDNK"
     gene            complement(5244..5468)
                     /locus_tag="PC592_000633"
     CDS             complement(5244..5468)
                     /locus_tag="PC592_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDF4054647.1"
                     /translation="MAQKTGALIFDEQTDRYDIRFDIADYYGGLHCGECFDVFTGGKW
                     KPTRIEMSAAQEWYLVGIRAEDLNGLRVRI"
     gene            complement(5483..6403)
                     /locus_tag="PC592_000634"
     CDS             complement(5483..6403)
                     /locus_tag="PC592_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4054648.1"
                     /translation="MAVFRVERNKGYTVMSNHHLRNKELSLKAKGLLSQMLSLPEDWD
                     YTLAGLSFINREKIDAIREAVKELERAGYIVRSRERDEKGRLRGADYVIFEQPQTPPV
                     SDLPTLENPTLDNPTLEKPTQKKPTLENPTQLNKDIQKTNLPKKEKSNIDLSSTDSIP
                     IHSLNPLPYDGEAAEPPERKRKEATDAYSVYEEIIKDNIEYDHFVRYGQVDKDRLDEI
                     VSIILETVCSKRKTIRIAGDDYPAELVKAKFMKLNSSHIEFVFDCMKENTTKIRNIKQ
                     YLKAVLFNAPNTIDSYYTALVAHDMATGKI"
     gene            complement(6614..6976)
                     /locus_tag="PC592_000635"
     CDS             complement(6614..6976)
                     /locus_tag="PC592_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005422970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054649.1"
                     /translation="MKNVLLDKGIILPSGEISKDKVNLVTGAITQPFAEMVWVTTGGD
                     METVNRLTDVLVTMNTPADRGKLFKIIKMLYGLMGLPFSEEAEPMDADPAVLEYFIFS
                     FTADFGEVIQDLIAEEAE"
     gene            complement(7149..7976)
                     /locus_tag="PC592_000636"
     CDS             complement(7149..7976)
                     /locus_tag="PC592_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF4054650.1"
                     /translation="MPKGSNQKFKLYRLAEIMLEKTDDEHYITMSEIKESLEEYGITA
                     DRKSLYADLKDLEILGIEVEGEPVKNKYHYHVINRPFELPELKLLVDAIQSSKFITEK
                     KSNTLIRKLEKLVSKYDAQKLQRQVYVSGRIKTMNESIYYSVDAIHNAITENKKIKFQ
                     YFQWNVKKEMELRHGGAYYYISPWGLSWDDENYYLIGYDSEASMIKHFRVDKMLHIAL
                     LDENREGKEHLKKMDMADYAKKSFGMFGGKEQTVKLLVDNTLSGVIIDRFGKNVIFY"
     gene            complement(8117..11218)
                     /locus_tag="PC592_000637"
     CDS             complement(8117..11218)
                     /locus_tag="PC592_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HDF4054651.1"
                     /translation="MAMNRNMTMAEKEVRDYAQKQMERAEQWENILFTEEQKEQVLEY
                     AAMTGDDYDIRKMIRDLADAVRSSDEEKVDEILRDAREEIDEFPDRSVGMAELKGYGY
                     TADDMFPLRQEMALELHRVGEKVYCLQSEGTHGDYASREMILEHEGLYGIEKEAWQRM
                     QEQEDEIDFEEAGLYQPPMIDLDRNEALRMFDAGETVYLITTYPRPIAVRKRMEIERG
                     PERYQMEREDVERIRTLEKRMQEYPQITSLKEAKLLLGTENRYGIYQIIDGSPGRKYE
                     FMDLNFIERHGYQVKKEDYELIYSDEMHYGDTLDSLYEKFNIAHPEDYTGHSLSVSDI
                     VVLNENGNVKAYFVDSISFRELPDFLQLEPELNQEEVAYRIGDQYFAIQVATEGYDYS
                     FYDKEYKLMDGGILENPDISMRQAIQDILEDEGLEQLERIPVDYDELQEKAEEVEAEI
                     LQEVRSQRKRVPVISDYIKAEAGLNGMSRSEIEETIWAIAQAEIIENDLDARIQAVRV
                     YGSRTRDGLYKQDSDVDVVIAYEGTVREDDLFSALNEAGYKVGNMRVDMNPIRPDKTG
                     TLEDFLEKSERYLDEKTEQMKARGEYKPLAKVEELEEANYNMIDNVLNNMPPKKEPYL
                     EYYAAECDEYHSLGKIYKSTNLDEIFAKYREIIDDPTLSYYGNGMGIIYRDPNDTFYD
                     EAEVSLVSRKSIRGDSLDDVAFLAALPMVHEALEKIVEAFPDFRYYPPKELDVHYYPE
                     KMNADELAAALDQLAEDFDHYDYHDNFSPEEDMVETVALELRCGYAHRYIPFLKDIID
                     EECEESPRAEELLEKLKAYQPEIPETAVPVVRINFCEDKEMDISGYQKLGSLDEITAK
                     MDAELASQADSKTGMPEKTVQMYFTIYYPDHDQMQELKGKINIGDGNGGIVSQLKNQN
                     EMKMHDESWLNYQKGKGEESFQAYIADLTDMQEHVLPYLQSFCSLEERAPERSVESTT
                     VSKSEMEAGKTITSGKNEKAKPVEPVKKSIHERLKINKEIIAKQQGKDEPERGVGKDL
                     RTV"
     gene            complement(11232..11996)
                     /gene="srtB"
                     /locus_tag="PC592_000638"
     CDS             complement(11232..11996)
                     /gene="srtB"
                     /locus_tag="PC592_000638"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HDF4054652.1"
                     /translation="MKRTEKVLLIVFLVVTLICGKYLLDYWQDSYDNRQNYRQVEEIA
                     FPEKDTEEDGTGSNADNPMTEIDDFDYQALLDENADCIGWLKIDGTDISYPVVQGEDN
                     EFYLRHDFQKNYAICGTLMLDCRNDIDAGQEHLIIYGHQMKDGSMFKQLNGYKKEEFY
                     HEHKEITLYLENQKYQYEVAAVYVTNVAQSGGYYDFLHKETRKQQMDYLQKMAAYQLY
                     PLGVTVREDDELLSLSTCEYSSTNGRLIVLARRIGA"
     gene            complement(12178..13638)
                     /locus_tag="PC592_000639"
     CDS             complement(12178..13638)
                     /locus_tag="PC592_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011133547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HDF4054653.1"
                     /translation="MSMIKIENLTFSYPTSYDNVFENVSFQVDTDWKLGFVGRNGRGK
                     TTFLNLLLGKYEYSGKILSSVQFDYFPYPVSDKNRITEDILQEVCPLAEEWELMRELS
                     YLDVDVDVLWRPFETLSNGEQTKVLLAALFLNEGHFLLIDEPTNHLDAKARKSVATYL
                     KKKKGFILVSHDRRFLDDCVDHILSINRANIEVQRGNFSSWMSNFEQQQEFELAQNER
                     LQKDIRRLQQSAKRSAVWSERVEASKIGAADKGYVGHKAAKMMKRSKSIEARQQQTIE
                     QKSALLKNVETAEALKIQPLNYHTDLIASLSNVVVCYDGISVCEPVSFEIRQGERIVL
                     DGKNGSGKSSLLKLVVGQSIDYTGTVTLGSGLVISYVPQDTSYLCGTLSEFAEENNLD
                     ESLFKAILRKMDFERIQFEKDIKDFSGGQKKKVLIAKSLCEKAHLYVWDEPLNFIDVY
                     SRMQIEQLITEFAPTMLLVEHDNVFRDTVASNIVNI"
     gene            complement(14089..14235)
                     /locus_tag="PC592_000640"
     CDS             complement(14089..14235)
                     /locus_tag="PC592_000640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054654.1"
                     /translation="MKFVIGGALTILFWDDPVTAFFGKSKKLRHSLGRPSRSDFVHFE
                     FYGQ"
     gene            14378..15220
                     /locus_tag="PC592_000641"
     CDS             14378..15220
                     /locus_tag="PC592_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013976755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4054655.1"
                     /translation="MYEDIFELVTIAAQKKNLKESTTKAYCHALSPFLNATGKPWQEL
                     TVADADDYLTTKRRMGILPETYNHYYGALRFMYKRVLKLNWDEDEIPRMKRDRSLPTV
                     LSREEVNAILDVTTNLKYKAIFAVMYSGGLRVSEATHLHYDDISRSNHSIHIRNTKNR
                     MDRYTILADRTLDILTQYWFQCQRPRNILFPSQTTGEYLDISAVNQVLRRSSERAGIP
                     KHVTSHAFRHSFASHLLEDGCDIKYIQALLGHLDPKSTEIYLHVSNKTLLGIKSPFDI
                     QEDS"
     gene            15220..16371
                     /locus_tag="PC592_000642"
     CDS             15220..16371
                     /locus_tag="PC592_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005343049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HDF4054656.1"
                     /translation="MKHPTVQDIFLRFYPEYLDKYKPSSQQFKVANCIINCKTGAYGA
                     NVSMCEDCGHLQIHYNSCRNRCCPMCQALPKEMWIDKRREDVLDAPYFHVVFTVPQEL
                     NSLIYSNQQLLYDAMYHSVSATINELTEDTKYLGAKIGYICVLHTWGSEMNYHPHIHV
                     ILLGGGLTSNNQWRDKGEEFFLPVKVLSKLFRGKYLDELKNLWEERKLQFHGSSEKYR
                     NHYAFKELLNTCYEKDWVPHCKKTFNGAQSVINYLGKYTHRIAISNHRIIRMDEDTVT
                     YYVKDYREEGKWKEFTISGVEFIRRFLMHVPPKRFVRIRHYGLLCTRTKTRHLTLCRN
                     LLGCKQYLSRLKDLDTPQILETLYGIKVTVCKRCGGHLRKPQQRIPLRI"
     gene            complement(16763..24442)
                     /locus_tag="PC592_000643"
     CDS             complement(16763..24442)
                     /locus_tag="PC592_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF4054657.1"
                     /translation="MANKLYAMEQLTEEVAKDIAAKPEEWMRFLDTASRLYKYTFDEQ
                     LLIFAQRPEATAVASMEVWNKRMYRWIRKGSKGIALIDYTSSPKNRLRYVFDISDTYK
                     VRNLGKDPALWVLPQDDRFLAADYLQRAYGLDEGDGGLAGTLHQAAQESVREWLPDAF
                     DELKQDVQGTFLEELDEQNQEVEFRDLMTDSVWYVLLKRCGMDTEEYLSVDSLRHITD
                     FNDLRVLGHLGTAVNEICRPILMQLGRYVLMDLENDRKTVAKESEVVYNEFNTLIRES
                     GEITPEPEIEENKEVTEHERDHLQQERGLSDPGYQTGGDQGNHREIRDDAEGISEEPQ
                     ESQIQHTGTAEQAGQPSDESGQRSQTESGRPDHAASGESPGTGEISRQHGMDPSHEPD
                     PRTGRGDGGSGDYIQLSLFPTEEEQFGEIRKAAAALTQPAAFFVSDEIVDDVLRTGSG
                     RKNTLFHITAKLVEGIDHEKLRSFLIQEYGTGGKGFEFSGQKFSVWYDGDGMRFRRGE
                     SARHNYDRMLTWEEAANRIQDMYDAGTYVSNVIMQNSIKVECDELSSQLALHFRDTGA
                     IRGIYSHTETTERFRAGLDDPKQTREYYQMLEELERDMERHPENYMRYQIRNNPIYKQ
                     RVYDLGRTLDWSRQEEIIIPPEMAFITQDEIDSVLRRGGNVAGGRSRIYEFFMEHHDE
                     KEAADFLKHEYGDGGCTPGIQGSDLSDEWHDAKGIRLSKGQISNPSLTTLVKWKQAAS
                     RTRQLIRMDDFLSPEELEKYEERQEAQRLADMEEVKQSLGTEEVSEEVEEVHAEENVE
                     DKPEESGQPLRAEDVQNLVLVNRQYSSVSRTTEYDFTCEIRGEQDILHYMVEYHDDGE
                     GFTIHTEKDDIWERMSEPELERLERVLEREALYFQYHEDIENAANLEELREVQYSIME
                     NESIYFRQISERVWSEYGQRERELSVEIPPVNFHITDDQLGYGTAKEKFRANVMAIRV
                     LKKCESENRYASPEEQEILSNYVGWGGLPDAFDESKASWSEEYQELKDLLTKEEYAAA
                     RESTLNAHYTQPVIIESMYQLLQNLGFEKGNILEPSMGVGNFFGMLPDKLQQSRLYGV
                     ELDSISGRIAKLLYPNADIQIKGFEKTDYPNDFFDVAIGNVPFGSYKVNDRQYDKYHF
                     MVHDYFLAKTIDQLRPGGVAALITTKGTMDKASPEVRKYLAERAELLGAIRLPNNAFK
                     ANAGTEVSADILFFQKRESISMEEPEWVTLGEDVNGISINRYFITHPEMVLGTMAEVS
                     GPYGMETACLPLEGADLAEQLEDAVAKIHGTMVPAVTAETELDEIMESIPADPSVRNY
                     SFTVVDDQIYYRVNSLMNPVKLPATTAERVKGMVEIREVVRELIALQMEENATNEAIQ
                     ELQVKLNQVYDAYTEKYGVIGSNANKRAFSDDSSYCLLCSLEELNEDGTLKRKADMFT
                     KRTIKKAVAVTSVETAAEALTISLNEKARVDLPYMAGLTGKTEEKVAEELTGVIFRDP
                     VNGQWETADEYLSGNVREKLKMARIFAENHPEFTSNVNALKQVQPVDLDASEIEVRIG
                     ATWIAPEIYRDFMVELFDTPGYLVGRVIDIRYSEASGAWNISGKNADSDRNVLTTATY
                     GTSRINAYKILEETLNLKDVRIYDTKLDAEGNEIRVLNKKETMLATQKQDAIKEAFKD
                     WIFRDQEQREKLCRIYNERFNSIRPREYDGSHLTFPGMNPEIELRPHQKNAVAHQLYG
                     DNVLLAHVVGSGKTYEMVAAAMESKRLGIAQKSLFVVPNHLTEQWGAEFLQLYPGANI
                     LVATKKDFEPSNRKKFCARIAMGSYDAVIIGHSQFERIPLSEERQKKIIEEQIEELEE
                     GIQQAKLESDGSRFTVKQLEKTKKSLRRRLEKLENKEKKDDVVTFEELGVDRLYVDEA
                     HYYKNAFLYTKMRNVAGIAQNEAQKSADMFNKCQYLDEITGRKGITFATGTPVSNSMT
                     ELYTMQRYLQYGKLNRMGLGHFDSWASTFGEVVTSIELAPEGTGYRAKSRFARFYNIP
                     ELMSMFKEIADIKTADQLELPVPEAEYETVVLKPSEHQKEIVESLGERAEVIRDGGVD
                     SSVDNMLKVTNDGRKLALDQRLVNPLLPDDGDSKICACVEKSFAIWKETASKRSAQLI
                     FCDLSTPKGDGTFNVYDDLKKKLMAKGVPEAEIAFIHDANTEVKKTDLFSKVKSGQVR
                     FLLGSTAKMGAGTNVQDRLIALHHLDVGWKPSDLEQREGRIIRQGNRNKKVHIYRYVT
                     EGTFDSYMWQLIESKQKFISQIMTSKSPVRSCEDVDDTALSYAEVKALATGNPAIKEK
                     MALDVEVSKLKLLKANFVSNHYRLEDDIAKNFPQQIAVLRESIEGFKADMEQYQANKT
                     TDPEKFVMEVGGTVFYEKKEAGAALLAVCQSMKQADAMINVGQYQGFSIRLKFDSWNK
                     EFILSLKNENVYRVSLGSDENGNIIRINNALEAIPQKLAEAERKLETVQGQLKNAMEE
                     VKKPFPKEEELNQKLERLSELNALLNMDEKETVVEGEEEQGEEKEEHQSLHNRITAIK
                     QNSQRQDGKEPAMRTSEVCIG"
     gene            complement(24460..25101)
                     /locus_tag="PC592_000644"
     CDS             complement(24460..25101)
                     /locus_tag="PC592_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HDF4054658.1"
                     /translation="MRRKYGIDQVSVRLVKEAPILSEKEISTPEDAIRVLGDTFKDYD
                     REVVGVVHLRSDNVPINMTIISMGTLNQSLVHPREVLKAAFLSNAASILLFHNHPSGS
                     LKPSKEDIALTGRMQQLCMLAGIPVIDHVILGNDQSYFSFREKQILPMEQIQYSVDLN
                     DINLKVAEKEAENYGYEKPHKKSIKESLEENRKKITSGQKTSGVKKKRETTIE"
     gene            complement(25079..25225)
                     /locus_tag="PC592_000645"
     CDS             complement(25079..25225)
                     /locus_tag="PC592_000645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054659.1"
                     /translation="MSSKMKKEERKRLSGYLRKCLESQKDQEFILQIPLKRGASESEK
                     KIRN"
     gene            complement(25222..25539)
                     /locus_tag="PC592_000646"
     CDS             complement(25222..25539)
                     /locus_tag="PC592_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HrcA family transcriptional regulator"
                     /protein_id="HDF4054660.1"
                     /translation="MYMSEWCLYGDDIREKFERRLEPDSLEGELIRYKEVLGEEFGLK
                     ELLTIQDLRVKVLIAQAINNVPEFLLDQIGKARNSYEFPSLVRELERIADVMEEVVEG
                     EGE"
     gene            complement(25600..26688)
                     /locus_tag="PC592_000647"
     CDS             complement(25600..26688)
                     /locus_tag="PC592_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054661.1"
                     /translation="MMNRKDFFEYVKDNVKDYLPEKYADANIHLQEVVKKNGLTLTAV
                     VIPAKDTNITPNVYLDSFYQEYRNGKSPDACVGDVADLWIEKMDTDLDVDVNGMMDYG
                     NVKDKLQVRMCDPEKNREWLEDKAVTMHGDFAAYYTVNLSENKDGIASVSVTKALLEA
                     WKIDVQTLHQDAMASDKNRGPALYAINDLMESSIMGEKPQNLLNGERRAEEFFMPMFC
                     LTNETKMNAASLILHEDIRKQIGEFMKGDFYILPSSIHETLLLPDNGDFDVKALNAMV
                     KEVNATEVALEDILSDKVQFCDGRTAVMENAEKREARLEKEKAAAAEKPAEKTGIHGK
                     LEKAKEEMKAGDVLVKPQGKTRDTAMVM"
     gene            complement(26695..26835)
                     /locus_tag="PC592_000648"
     CDS             complement(26695..26835)
                     /locus_tag="PC592_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054662.1"
                     /translation="MKKTMNTVQAGREMQERSFKRMMAYQKKAEQAVNKKRMNQHMIR
                     RG"
     gene            complement(26914..33282)
                     /locus_tag="PC592_000649"
     CDS             complement(26914..33282)
                     /locus_tag="PC592_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDF4054663.1"
                     /translation="MRRTGHLRRLVSGFLAGLTMLSTVLSPMTAYAAEPKAEEKPPLY
                     EEVKDLLDEDEVVKAKDFEITVGSEFDVTCDFTGLEIKDDKKVKVTFEEAKNEEGKDF
                     ALDHADSYKAVYYVEPVNEAHPKYQISRNLIVKEAETEVQAASEGGGEDAGSGGTEEA
                     ADDGEADSQTFSAEESETTETSMETEAATEPVTEAEPETETVESTEVLPEEELDAALE
                     ESEGQETVDSETGLSVSDVLEQGEEQGIDMLSLEEGETVQFQAQALFASARSTTSVSV
                     TRGAYYYYADYGLGSYLTAPYTVKFGDVTATAYCVQPSKPGPGDGTYTITKLSDGKTL
                     AKVCYYGTKASGDEGFFAEKHPDFSTGKRFIITHLAAAYANGSSDAFSGTNSTGQALA
                     MELYNYCVSQPEIPDVAMSFSNAKVKAYIDGNSQRTEEITFKADALQTITMKLPSGVK
                     FHNVSTGKTSAAGASVEVSGGTKFYLSAPLTQAEDVSGSWAVTMKGSITKDYSAYKIT
                     TGSSTQDLALVFGEGVTDEKYVDFSVEWVKMAKIEIVKKDAGSNAKVAGAVYGIYSDE
                     AGKNLIAKMPATDANGASSITIEKTQNTVYLKEISVPNGYVLDTKAYGINLVIGGTTK
                     KDVTDKEQFADLTVYKEGEVLTGASVTDSGVVFQYTKQRLKGAVYNVYAGADIKAADG
                     RVIFQKGALVKEGLTTGEDGSATLKNLHLGTYVVTETKAPADYVCKGESKTVTLSYAG
                     QNVEVAVGNVTFANDRQKASVSVVKQDDTTKNPLSGGIYGLYAAENIADVSGNVVVGK
                     DTLIEKATTGTDGNAVYQADLPINHSYYVKELQAPANYFRNSEDVFSFRFQYTNDKQA
                     SVAFTHTFENERVNATIHLVKKDKETGRNTQGDAAFEGAVYGVYARENIIHPDGKTGI
                     LYKAGSQVATMTVDKKGDASVVDLYLGKYYVKEITPPIGYLIDEGEYDLECSYEGDLV
                     KTVERSTESSEQVMKQPFQVIKAANNGKTDADLLKGAGFTAYLKSSLKTNPDGSYDFA
                     SAKPVVLTADGKTEMFTDAKGYACSIPLPYGTYLVKETTTPHNYKPVDDFLVTISENH
                     PDEPQIWRILLDDEFKAKLKIVKKDDETKRPVLVAGTEFKIYDLDHKKYVEQVTTYPT
                     TVTHKSYFTDSQGYLILPNNLSIGHYRIEEVTAPDGYTLNQNYVEIAVDSNTAYQMDS
                     VSGDVVIEVDYENHPVKGKLTVYKKGEMLAGFNKDFIYEEQFLKDAVFEVYAAEDIYS
                     TDYQKDADGKRIVVYAKNTLVTTITTGDDGMAVAENLPLGAYRVVEKTAPDGFVLNPE
                     AAEVVFVYEGQDTPVVEQEVTVGDERQKVAITVEKQDAENGAVVAGAVFGIYNKEDIT
                     ADGKVIVEADTLLQEMTSDEKGQAGCTLDLPLGSYYVKELKAPAGYVSSNEVLNFDAS
                     YQGQDVETVVLKAVKKNQPTTVEITKSDITTGTELDGASLKVLDKDGNVVDEWTSVKD
                     APHVIKRLVVGETYTLREEFAPYGYLKATDITFTVEDNGDVQKVEMKDEVPTGLLIIN
                     KKGEFLDKVTLLDNAKGTVEHLFEYITGSLTEVTFHVYAAEDIKAADGVSEDYFKADE
                     LVGTITTDTNGIAQLGDLPVGKYYVKEAETAHGYVLDGEPRYVDLSYRDQDTPVVTYD
                     EAWQNNRQKVKVTVLKKEKDTERVLAGGIFGLFTREDIKNASGDVLLEADTLIELKTT
                     DENGQITFTADLPVDGNYYVKELYAPDGFVTTNEEQDFIFEYAGADQAEVSYDFTFEN
                     EATTVELTKSVLTTGDELPGAHLKVTDEDGNVVDEWVSTEEAHVIKELVVGKTYTMTE
                     TKPADGYVTAESIEFTIENTAEIQKHEMKDDVTKVQISKTDITGDQEIPGAKLTILDE
                     NDQVVESWTSTEEPHYVEKLPIGRYTLREEQAPKGFILTADVSFEVKDTGEIQTVVMK
                     DDTAKGKVILNKTDKETGEPLKGVEFELRDSKGKVLETLKTDAAGHAESSLYEIAEYK
                     DGKFAGEKKYYLVETKTLDGYTLDETEHEVVFAYKDDSTPIVEVTFDLTNDKPEVPQT
                     TEGTPGTPSADNPKTGDETNLWIPVVLLAVSVSGIAGLLADRRKRKRK"
     gene            complement(33348..35420)
                     /locus_tag="PC592_000650"
     CDS             complement(33348..35420)
                     /locus_tag="PC592_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005344197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF4054664.1"
                     /translation="MKLVIAEKPSVAMALAKVVGARERKDGYVEGKEYLVSWCVGHLV
                     AFCDASEYDERYKKWRYEDLPIIPEEWKRKVLDGTKKQFQILKKLMNSKEVDEVICAT
                     DAGREGELIFRFVYEQAGCKKPVKRLWISSMEERAIKEGFASLKDGSCYEDLYQSALC
                     RAKADWLVGINASRLFSVLYNQNLKVGRVQTPTLAMIVDRNQKVKEFVKEKYYVAHLT
                     FGEFDAVSEHFQKKEEADQVAADCSERMCQVEKEDVQTKTVRAPKLYDLTSLQRDANR
                     IFGYTAQQTLDSVQEMYEKKLVTYPRTDSQYLTDEMGNSTKQLIQLLLSRMPFAEGIA
                     YEPDISKVLNSKKVSDHHAIIPTSEVEKADLQKLKEKERNILYLISARVLTATADPYI
                     YETHKCQLTCNFHTFYFNARKTKQEGFQAIEKKLKQFLGVREPEQEAEFDLYLGRNIG
                     PCSTSVSENFTQPPRQYTEDTLLAAMERAGNEELTEDTEKKGLGTPATRAGIIEKLIQ
                     SGFVKREKKNLVPTDAGNVLVTVLPDEIKSPKMTAEWEMALNHIAQGTETAEHFLNGI
                     TDMLGELISRYHSISEEESSRFPGTAMGEVIGKCPVCGSDVREGKKNYYCTGQECRFS
                     LWKDDHFLASQGKKMDKATAKKFLKKGKVHYKDLVSKRTGKSYEATVEMVADSEGKAQ
                     FNLHFPQR"
     gene            complement(35422..35982)
                     /locus_tag="PC592_000651"
     CDS             complement(35422..35982)
                     /locus_tag="PC592_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007593032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine methyltransferase"
                     /protein_id="HDF4054665.1"
                     /translation="MKKYPVIYADPPWQYRVYSKKGLGRSAESHYPTMGIDEIRALPV
                     AELAEKDCALFLWVTIPCLLEGLSVLQAWGFQYKTIAFVWIKQNKKADSLFWGMGYWT
                     RSNAEFCILATRGSPKRQSAGVHQVIVSHIEEHSKKPQEARERIVQLMGDVPRIELFA
                     RQKTPGWDVWGNEVESDIDMESRKDE"
     gene            complement(36001..37380)
                     /locus_tag="PC592_000652"
     CDS             complement(36001..37380)
                     /locus_tag="PC592_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF4054666.1"
                     /translation="MNLEKMKEQRAPGRHRKWGSNVKRGVFAVTTFLCMATPFFSARS
                     IYAAESTNPAIAIEKPDGWKQGDTSVSITVDASQMGEGFKVAKIEAKTGKDGSWQDVT
                     ESRSITINGNQTIYVRVTDAEGTVYEQNRSIRCYDTEKPTLSASLTDGVLTIQGNDAV
                     SGISAVTVNGTTYTELSDGKLKVQLTQKDFTTKQIEITVTDGAGNTSDKYTLQNPYYE
                     WAVRQAQQQSTANSDMSTTGSAATTEETATSPLPQDAQASEPTEARGTVDDRTVTGIE
                     EELAASGEDAENITQTATEGTKEFYTISTKSGKVFYLVIDNSRSQDNVYFLTEVSEKD
                     LMNFTLSDTVTLPEVDTVYAEPETEEPEPTQEPEEEEQETEEVQMPEDKSPVGSYLLI
                     GLAAAGALGAGYYFKVYKPKHEYDDEDEYEDDESEEAEEPAEPDDAEEETLPDEEDPE
                     EVLEDEEES"
     gene            complement(37319..37639)
                     /locus_tag="PC592_000653"
     CDS             complement(37319..37639)
                     /locus_tag="PC592_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HDF4054667.1"
                     /translation="MKSLEKAVADYEKAKEKMEASRARYEADLKRFKAAEAAKTEAEN
                     LEIVRIIRGMDMTIPELNAFRERMKTELPTLAGFQKEETRADDEFRENERTEGTGQAQ
                     EMGQ"
     gene            complement(37677..40457)
                     /locus_tag="PC592_000654"
     CDS             complement(37677..40457)
                     /locus_tag="PC592_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDF4054668.1"
                     /translation="MAEQRMKAREKTVQKMTKDGLVEENLADKSTVRVSSRTRDVQMS
                     KKDTGKGMDLSNRRGTREDSTDPVRHSVQNSRDAPAKAQTVDKAKSRKMIREQAEGSS
                     KLSLEEKKNGSGKLQEKHTDLAQSRGDARKKQNGGSKKPGQKQRLKFAYEETAEAVRD
                     GNSSAKLNRMDADGVNFRHDAQKKRNQKMAHTEAERKNAPKKHSMKEKVYQENAESAG
                     AKKKSRLKFEGESPKDTSLVKKAGTAAAVSVHRQVRKNDDGNAAVEGANSLAEGSEGL
                     YHLEQRSARRRNRRKSRSSAYQAKKTAQAAAESSINQERSYLKKLIQKQRIKKEYSKA
                     KQSEQAMGTAAVGTIDYIKKIGGKVTNFFKEHRKVYISIAALIGMMFLIMTSVTSCSS
                     AFMQSLINYTGTSYISSDEAIRQADLYYTQLETNLQERINQMESEEPGHDEYRYNIGP
                     IEHDPFVLISYLSAKYEEFTFEQVKPELDRLFALQYQLETEVVNETVTETTTVRVGES
                     LGNVVTSGYCNCPICCGIWSGGPTASGVYPTANHTLAVDASNPFVPMGTKVVMNGVEY
                     TVEDTGAFARYGVQFDVYYDSHSAASAHGHQTWECFLADDNGSREVEVTRTRDVDVLN
                     VTLNSGSLTGICQSRLGIFQRELFAAYNETKGNLQMFGTPFDFNWYYNVSSYYGYRIH
                     PISGANQLHNGVDIGVPEGTEVLAGLTGTVTTSAYNDSYGNYVVIKDSKGYELRYAHL
                     KSRSVFAGAAITKGDVIGLAGNTGNSTGSHLHMELLKNGERMNPIFYLETGEGTIFGG
                     NEYTSEAAQRLLQEAARYLGTPYVWGGYSPSGFDCSGFVSYCLTNSGVRNTGRLTAQG
                     LYDICTPVSESDVQPGDLIFFTGTYNAGVPVTHIGIYVGGGQMIHCGHPVQYTSIYSS
                     YWQSHFYGFGRW"
     gene            complement(40571..40798)
                     /locus_tag="PC592_000655"
                     /pseudo
     CDS             complement(40571..40798)
                     /locus_tag="PC592_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
     gene            complement(40960..42843)
                     /gene="ltrA"
                     /locus_tag="PC592_000656"
     CDS             complement(40960..42843)
                     /gene="ltrA"
                     /locus_tag="PC592_000656"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF4054669.1"
                     /translation="MTMKKKKQLLCEDNLRHNEYYGMQNTIDNLYQASLNGEVFTDLM
                     SVILQRENILLAYRNIKKNTGSKTNGTDNLTIEDIGRCSPDEVVEKVRFIINGSEHGY
                     RPKPVRRKEIPKPYDPSKTRPLGIPCIWDRLVQQCIKQVMEPVCEAKFSKNSYGFRPN
                     HSVENAIARSYQLLQHANLHYVIEFDIKGFFDNVNHAKLIRQIWAMGIHDKKLIFVIR
                     RILKAPIKLEDGTFITPDKGTPQGGIISPLLANIVLNELDHWVESQWQWCPICKRNTR
                     PDNGYRQAKKSNLKEMFIVRYADDFRIFCRTKDSAERTKCAVTLWLKERLKLEISEKK
                     TRIVNVRNHYSDFLGFKMKVHRKGNKLVVISHIADKNLEHKREKLKEQAKRIAHPRKI
                     YGEQGEIRLYNSMVTGMQNYYCIATHVNHDCASLNRTVMTLLTNRLSTRTGNRLVKTG
                     RELTEFEKARFGKSKMMRYVAGTNEPVYPIGYTQHKNPLFRKKSWNYYTPEGREGIHN
                     CLRINIPMMLALMRQPVYSNSAEYADNRISLFSAQWGKCAITGVEFSSVGEIHCHHKL
                     PRHLGGTDAYENLILIKNSVHKLIHASKAETIYKYMDLLQLDNKQLIKVNHLRELASM
                     QPI"
     gene            complement(43576..45813)
                     /locus_tag="PC592_000657"
     CDS             complement(43576..45813)
                     /locus_tag="PC592_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4054670.1"
                     /translation="MAKKKKQAQQQCLEAAARKNRQERRKRNDKKEREKEKLRKKQEK
                     ERKRQKNIPHTAQQSIPYQRMFADGICQVSKNFFSKTVQFYDINYQLALNEDKTTIFE
                     NYCDFLNYFDSSISVQLSFINQQVDVAEFEKSIDIPDQNDDFNEIREEYRTMLKNQLS
                     KGNNGLVKSKYITFGIEAESLKVARPRLERIEADILNNFKVLGAQAHPLNGVERLEIM
                     YHVFNQDRIEPFRFNYKMLPQTGLKTKDFIAPTSFNFSKNSSFMMGKTLGSVSYLQIL
                     APELTDRMLADFLDVDESINVNIHIQSIDQTSAIKMIKSKISDLDKMKIEEQKRAVRS
                     GYDMDVLPSDLVTYGEEAKNLLEDLQSRNERMFLVTVLVMNTAKKRQKLDNNIFQVQG
                     IAQKYNCSLRPLDYQQEAGLMSCIPLGVNRIEIQRGLTTSATAIFVPFTTQELFQEGE
                     ALYYGLNALSNNMIMVDRKRLKNPNGLILGTPGSGKSFSAKREITNCFLITEDDIIIC
                     DPEAEYYPLVQALHGQVVRISPVSTQYINPMDLNLNYSEEDNPLSLKSDFILSLCELI
                     VGGKNGLEPVEKTIIDRCVRLVYQEYLSDPVPEKMPILQDLYDLLRGQDEPEAQRLAT
                     ALEIYVTGSLNVFNHRTNVDINSRIICFDIKELGKQLKKIGMLIVQDQVWNRVTVNRS
                     AHKSTRYYVDEFHLLLKEEQTAAYSVEIWKRFRKWGGIPTGITQNIKDLLASREIENI
                     FGATR"
     gene            complement(45698..46159)
                     /locus_tag="PC592_000658"
     CDS             complement(45698..46159)
                     /locus_tag="PC592_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF4054671.1"
                     /translation="MAYVPVPKDLTKVKTKVALNLTKRQLIFFSLAAVVGVPLYLLAK
                     KPLGSSVSAILMVTVMLPFFFMAMYEKDGLPFEKVMGNIIRQKFICPAKRPYKTENFY
                     QAVDSLVKKEGVPDGKKEETGTAAVPGSGGKKKPSGKKKKKRQKGKGKGKA"
     gene            complement(46188..47057)
                     /locus_tag="PC592_000659"
     CDS             complement(46188..47057)
                     /locus_tag="PC592_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054672.1"
                     /translation="MNTIIERITEAIKEILIGMIQNGLEGMFVEVNDKVGTIASQVGQ
                     TPQGWNTGVFNLIQNLSQTVIVPIAGLIITFVLCYELITMVTQKNNFHEFETYNIFLW
                     IFKAYVAIYLVTNTFNITMAVFDVGQHIVNGAAGVISGSTAVDASAAIATLTESLEEM
                     EIGELFLLAMETLLISLTMSILSVIITVIMYGRMIEIYLYTSVAPIPFATMTNKEWGN
                     IGNNYLKGLFALAFQGFFMLVCVGIYSVLVNAMTISTNLHGAMFSVAAYTVVLAFSLF
                     KTGSLSKSIFNAH"
     gene            complement(47069..47284)
                     /locus_tag="PC592_000660"
     CDS             complement(47069..47284)
                     /locus_tag="PC592_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HDF4054673.1"
                     /translation="MAFFTSAITTLKTLVVAIGAGLGVWGVINLLEGYGNDNPGAKSQ
                     GIKQLMAGAGIMLLGTTLIPQLATLFG"
     gene            complement(47359..49260)
                     /locus_tag="PC592_000661"
     CDS             complement(47359..49260)
                     /locus_tag="PC592_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDF4054674.1"
                     /translation="MTNKLKAKARVTLSALDMKKLILTNLPYLFIFLLADRASCLYRA
                     SPGADMGNKLLYAMEHADRILTGFLPSLYYMDVLVGAGIAAVVKILVWQKQADAKKLR
                     KGVEYGSARWGTAEDIKPFMADDFWMNIPLTATESITMESRPKNPKFARNKNICVIGG
                     SGSGKTRFFVKVSIMMMNCSMVITDPKGTLIEECGKMLAKGPPKRDKHGNVVKDKSGK
                     VVHEPYVIKVLNTINFSKSLHYNPFAYLKSEKDILKLVTVIIANTKGEGEKATEDFWV
                     KAEKLLYTALIALIWYEGDEDEKNMNTLIDLLNESETREDDENYKNPVDMLFEDLEKR
                     NPEHFAVRQYKKYKLAAGKTAKSILISCGARLAPFDIAELREIMSYDEMELDKVGDRK
                     TALFLIMSDTDTTFNFVIAMLQSQLFNLLCDKADDQYGGRLPVHVRVICDEFANIGQI
                     PQFDKLIATIRSREISASIILQSQSQLKAMYKDSADTILGNCDTMLFLGGKEKTTLKE
                     MSELLGKETIDLYNTSETRSNQKSFGLNYQKTGKQLMTEDEIAVMDGGKCILQIRGVR
                     PFYSDKYDITKHPNYRLLADYSEKNRFKVEKELDPKYSPKPDDEVEVMEMDLSEDGNE
                     QENNEERNN"
     gene            complement(49281..49772)
                     /locus_tag="PC592_000662"
     CDS             complement(49281..49772)
                     /locus_tag="PC592_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDF4054675.1"
                     /translation="MQEEVTQKTVTFCVRTTKMTADVLKKVIAAYLRHQKQKSAEKKA
                     QKNQPKQGKITVKELAKQNAGMTNIEITPKNIKSFERYARKYGINYALKKDKTKDPPV
                     YMVFFKGRDQDAITAAFREFSQKEIQKANRPSIHKRLAAYRSIVAGKTKGKARNKHQE
                     VSR"
     gene            complement(49855..50652)
                     /locus_tag="PC592_000663"
     CDS             complement(49855..50652)
                     /locus_tag="PC592_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4054676.1"
                     /translation="MTDSRNVADFLGEDGCLRCGVCGKRKQLRINFMGRDRVVGCLCD
                     CEAQARKEKEEQLRREEAQRELYQRKSVGLRDRRFWEWRFENDNGSNDKMLIARQYTK
                     NWEKMKKENVGLLLMGPVGTGKSFFAGCIANALLEQGERVMMTNFSRILNEMTNYQAD
                     KNQIVQNLVDYPLLIIDDLGIERNSEFALEQIYNVIDSRYCKMKPLIITTNLGLNDMK
                     DEALDVAHKRIYSRILEMCVPVYCGGADKRREEGTEKLGRMQSLISG"
     gene            complement(50649..51461)
                     /locus_tag="PC592_000664"
     CDS             complement(50649..51461)
                     /locus_tag="PC592_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF4054677.1"
                     /translation="MDYEYFRVEESEQFSFFRIPKALFTEKEFEGLSTDAKLLYGILL
                     DRINLSKKNGWVDADGYVYIIYTVAELQEVLHMSHTTVTKLLRELDSVHGIGLIERYR
                     QGCNRPSVIYVKNFVKRIRAKPAVYYPSGTQEICCPERKNLEVRSAKKLQSGTQKIGS
                     PERKNFATNNTDINKTDKNDTDRSKSRSSEKESTCLYGRFGNVRLSVEENRELRKLYP
                     YDFQRMIDQLSAYMKSTGKTYQDHFATILLWAGREELKTGSGRYDFEEGESL"
     gene            complement(51475..52398)
                     /locus_tag="PC592_000665"
     CDS             complement(51475..52398)
                     /locus_tag="PC592_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF4054678.1"
                     /translation="MSNQDYMPVECLLVPKALFKDARYCSLSTTAKVLYSLMLDRLRY
                     AAQNKWIDQKGRPYVIYPKSEMIRDLNSTRYRMDYAVSELESMGNMVRVVKDNGRPNR
                     FYINDISKMNEEEKTMMTINDLMTMVGPEEAEEIMDKMVTAAREIVDDLMKKGYIEII
                     REGCPEGGPLEDGVPPIDLGEDEFNPEDLSPMEFRCYCDENGNLDDEAIEDDASEFGM
                     DLAFGVIELLENDPDRIEAIRQYFNHVYKMESMKRFMAVVETTAVICGNSPEWIEDMH
                     ACNKGARRIYLKELVSVFNMYLNMFKNKEME"
     gene            complement(52391..52783)
                     /locus_tag="PC592_000666"
     CDS             complement(52391..52783)
                     /locus_tag="PC592_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054679.1"
                     /translation="MVMLNKEYMINHMRNENGSINIKNVVLAAACEATELFQCLIVMD
                     SNFTDWSRFVDRLEKNVERQDYEKVHELCQTMYAMRHLSEELEGLYLVRDDAELCSLY
                     YQIFVGMLDLTVFSTEAMVDLNGGKHDE"
     gene            complement(52796..53194)
                     /locus_tag="PC592_000667"
     CDS             complement(52796..53194)
                     /locus_tag="PC592_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF4054680.1"
                     /translation="MNTAIISGRLVRDPGYNETQNEKGLHKIAKFVLAVRRNYSDDVS
                     FIPVKAFAKKAEFVRDYLVQGTKVMVEGEIVTGSYDNKETGKKVYTTELFADRIEFAG
                     AKVQEKMPEPMEGDGFLNIPESMEEEMPFR"
     gene            complement(53209..53607)
                     /locus_tag="PC592_000668"
     CDS             complement(53209..53607)
                     /locus_tag="PC592_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054681.1"
                     /translation="MRERIKNKQITKEIRGQLPVIAPAMFRERGCSYCPYYAGSYEKF
                     PRCMMASCAWDDEEEHFHPVLRQMLPEFKRKMEKAEEKYLELKTAYELLMSMFEAEMA
                     QEELEKDECYDCCYAKCGPCIGLCYKTLKE"
     gene            complement(53823..54134)
                     /locus_tag="PC592_000669"
     CDS             complement(53823..54134)
                     /locus_tag="PC592_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4054682.1"
                     /translation="MTIMDVIKKALLPLAAMAFWLWMVKTIMGVTGNTDLFMFLFLAG
                     LPFGIHKMCIILIPRGYDVGGTVGMIALSVIVGGLLGSLMIPYYIVRAIYVTIRYIVK
                     R"
     gene            complement(54112..55041)
                     /locus_tag="PC592_000670"
     CDS             complement(54112..55041)
                     /locus_tag="PC592_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF4054683.1"
                     /translation="MAGKKKSTPIPLQSLDALFGTTSEEQAGIQQIALDNLHSFSNHP
                     FKVLDDDKMIELSESVRTHGVLVPGIVRIKDTGGYEIIAGHRRKRACEIAGLKTMPVI
                     IKDLTDDESTVIMVDSNIQREELLISEKAFAYKMKYDALKRQGKRSDLTSCQVGKKLA
                     AEDISQNSEDSTRQILRYIHLTELLPVLLDMADHKQLPFNTAVELSYLKKEEQDILLQ
                     YMGNHEMVPSMKQAQEMKKCSKEHLLTYSEIDCICCQGKTEKLQVKLPEKKLRMFFPE
                     SYTKEQIEDVIFKLLEEWADNKERVQNDNHGCD"
     gene            complement(55031..55816)
                     /locus_tag="PC592_000671"
     CDS             complement(55031..55816)
                     /locus_tag="PC592_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF4054684.1"
                     /translation="MAKIISVVNQKGGTGKSACAANLGVGLALMNKKVLVVDADPQSD
                     VSAGFGFRDCDNSNETLTTLMEMVLNDEDIPEDCFIQHTEEGIDIICSNIGLAGTEVQ
                     LVNAMSREFVLKQILNRVKDRYDTVLIDCMPSLGMITINALAASDEVLIPVEASYLPI
                     KGLQQLLKTIGKVRRQINPKLQIAGILFSMVDAHTNDARNNMELLHNAYGNQIHVFDN
                     YIPFSVRMKEAVREGQSIFKYEPKGKVAKAYMNFTEEVLEHGR"
     gene            complement(56107..56768)
                     /locus_tag="PC592_000672"
                     /pseudo
     CDS             complement(56107..56768)
                     /locus_tag="PC592_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(56837..57343)
                     /locus_tag="PC592_000673"
     CDS             complement(56837..57343)
                     /locus_tag="PC592_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4054685.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPNPYTEQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAVLGYWLARNYWGKGITTN
                     AVKEICKIAFEKYNLNKIHANVYSYNRRSSKVLEKCGFKIEEYCHNSIIKNRNMIDCH
                     VYSLIRTQ"
     gene            complement(57357..58283)
                     /locus_tag="PC592_000674"
     CDS             complement(57357..58283)
                     /locus_tag="PC592_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054686.1"
                     /translation="MSDILSRISNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSSIDPEEIHTLESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARAIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNDTVEMVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(58408..59190)
                     /locus_tag="PC592_000675"
     CDS             complement(58408..59190)
                     /locus_tag="PC592_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF4054687.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVATHEYRSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(59346..59966)
                     /locus_tag="PC592_000676"
     CDS             complement(59346..59966)
                     /locus_tag="PC592_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF4054688.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNAKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     KGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLKCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(60724..61260)
                     /locus_tag="PC592_000677"
     CDS             complement(60724..61260)
                     /locus_tag="PC592_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF4054689.1"
                     /translation="MQGGVDIRQVKSFVFPVISLIFLDQISKVLIGLFLMGFEIDITG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVIIGILHS
                     REISMKEYIYFCYRQFKR"
     gene            complement(61651..62160)
                     /locus_tag="PC592_000678"
     CDS             complement(61651..62160)
                     /locus_tag="PC592_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054690.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVELEVDNLKVISEKLEIINLQLVQRKNMRRKMFHWLF
                     ILLCSVIVIVFMVLGGLNSPYLNWNYTNPETAVFGVAFHAFECLFVRLTPIVLIGAII
                     GSFLTRKKI"
     gene            complement(62437..62586)
                     /locus_tag="PC592_000679"
     CDS             complement(62437..62586)
                     /locus_tag="PC592_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054691.1"
                     /translation="MNVNDNLKSINRELCVKTYDNFKILHDKEINRLKELKLNGYKLI
                     SSMKI"
     gene            complement(62607..62693)
                     /locus_tag="PC592_000680"
                     /pseudo
     CDS             complement(62607..62693)
                     /locus_tag="PC592_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606463.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            63573..64010
                     /locus_tag="PC592_000681"
     CDS             63573..64010
                     /locus_tag="PC592_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HDF4054692.1"
                     /translation="MDKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQSGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            64149..64937
                     /locus_tag="PC592_000682"
     CDS             64149..64937
                     /locus_tag="PC592_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4054693.1"
                     /translation="MKVVIIPGHTLTGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNVTTSTPGGTETIYKTNNEKTY
                     AERVNTRLATVFKNRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGVNKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALKQIDKL"
     gene            64985..65443
                     /locus_tag="PC592_000683"
     CDS             64985..65443
                     /locus_tag="PC592_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054694.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSNGKADLLYSCRLQKILKEIYINQSRASYMSGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(65543..65893)
                     /locus_tag="PC592_000684"
     CDS             complement(65543..65893)
                     /locus_tag="PC592_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054695.1"
                     /translation="MNNTITINISIIYLLLAILACIALVYLIIVLVKLHKILNTVGTM
                     LNENTQNINTTLNNLPSVVENFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(65895..66278)
                     /locus_tag="PC592_000685"
     CDS             complement(65895..66278)
                     /locus_tag="PC592_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF4054696.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLENKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            complement(66784..67167)
                     /locus_tag="PC592_000686"
     CDS             complement(66784..67167)
                     /locus_tag="PC592_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054697.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKEYLYV
                     SSMYAIKEAKLESRINSGRVKQYDG"
     gene            67516..68007
                     /locus_tag="PC592_000687"
     CDS             67516..68007
                     /locus_tag="PC592_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF4054698.1"
                     /translation="MNNQQQEVYKKLDELNIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            complement(68132..68869)
                     /locus_tag="PC592_000688"
     CDS             complement(68132..68869)
                     /locus_tag="PC592_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF4054699.1"
                     /translation="MKQNKYDDDKFFNKYSKMERSINGLAGAGEWHTFRKMLPNFKGK
                     RVLDLGCGFGWHCQHAVENGATSAVGIDISEKMLKEARNKTTFDNIKYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGDFVFSVEHPIFTAHGSQEWHCDK
                     DGNNLHWPVDRYFEEGLRKSNFLGEEVIKYHKTLTTYLNTLIKTGFEVLEIIEPQPEE
                     KLLDAIPGMKDELRRPMMLLVSAKKDK"
BASE COUNT        17706 a        16670 c        12675 g        21915 t
ORIGIN      
        1 cttctcattc tccgccaaca ggtcattgat tgtgaccttg tactttttca gttgcccgga
       61 gaagttctcc atctgcggga accacttttt cagcatggag agggcttcct cttttttctt
      121 tccggcgttc agcgggttaa tgccgtcaag ggcggcttca atggctcttg cctgccggga
      181 gagggaaacc gcctgtttga aaatccgggt ggggatatgc ttccggcctg tcttgctggc
      241 actttcccca cgctccaagt cgggatattt ctccaccata taggcgtgaa aatcgtcctg
      301 ccacttcgtc aggtttgccc ggttgccgat aatctcctta gcgcacaggc ggttgtcctt
      361 tgtcagcgga acaaaggtca aatgcaggtg gggcgttttc tcgtccatgt gtaccaccgc
      421 cgacacgata ttttcccgtc ctacccggcc aatgaggaaa tctgccgccc tttggaagaa
      481 cgcctgtatc tcttttgggg atttcccctt gaagaactcc gggctggcgg ttatcagcgt
      541 atcgacaaac cgtgtgctgt ctttcctcgt ccggcatcca gcctgctcga tacggctctg
      601 aatgaagtgg taatagcgtc cctccggctt gacgatatgg aagttgtatt tactccggct
      661 tgtgtcaatg tcggggttgc tggcgtattg ttctttctgt ctttcgtgat gggcttccag
      721 cggccttgcc gggttgccct tgtgcttctc aaaccgcaaa attgcgtgtt gtgccattct
      781 gctcctttcc ccattccttt cctatccggg gttttccaca gggaaaatcc cgccggaatt
      841 atctctgata cgataggaat ggaatggata taaataaatc atttttatct ttgtatttct
      901 atataccgtc cggttttcgt acttcaagag gggcggtttc cgtacttcat gggtacggtt
      961 ttcagtcctc cggcgtacca gaacgggatt tcttgaagtc agtgtttgga accgcttcat
     1021 aggattttgg gaaaatgcgg ttgggttttc cacagccctg cttctggatt tccaccagtc
     1081 cggcgtattg cagttcccgc agggtgttca ccgctttctg ccgcccacag tggagcaggt
     1141 caaccacctc gcagatgggg taatacagga aaatccgtcc gcagtcatcc gcccacccat
     1201 tcttgcggga caactctgtc cggcgcagga taaaggcgta cagaaccttt gcctcgttgg
     1261 acaggggctt gaatgtgggg gcttcaaaga ggaaattcgg gagccgggtg aagctgaacg
     1321 ccttttccgg ctgatggata tagatggtat ttgtcatagt gcgttttgtg gacggttaga
     1381 agcccgtttt ccggggcggg cgatacttta taccacctgc cccggtttgg ggcttgcaaa
     1441 gcctgataaa tcaaggcttt tttcgctcct aactgtccac agcagacctc cttttccgtt
     1501 cactttctgt tttctgccgc ctgtgaactc tggcggcaca gccggggcag tattttgccc
     1561 ggttggattt ggggacgaac acaccgccgc agaccacaca gcgtttcaag tccttatccc
     1621 ggaaaatctc cgcttccagc gtcccgtcca gcggcaagac cgcccagcgg aaccacttac
     1681 agcagaccga gaaagaaacc gtctgcgggc aggtgcaggt gtccccatcg tcaaggacaa
     1741 tgcagttgcc gtcctcacag caacagcact cccggcgtat caggctggcc gcctgtttcc
     1801 tctgtgccgg tgtcatgcgg taaagggaac cgtccggcct gcgttccagc ggcggcaagt
     1861 ctttataggg gttatttctc atgcgttccc tccattttgc tttccgttgc cgttttcccc
     1921 gaaaggattt ccagctttgg cacgctcccc gcagcttcgg gacattttgt cccgaagtcc
     1981 ggttccttgc ggtgcttccc cagccggggt attccttttc ggacggtcat tctgttttca
     2041 aggtgctgtc catcgatgaa ctatcctaag tctacacgaa aaaaatgcaa tccccggaat
     2101 tttgcgagaa ttgcattttg atgaagttta cactttggaa attgcatttt tgcaatcatc
     2161 ctgtataatg gaagtatgcg gaggaggtgc gtgtctatgg ctttacccgg aacacccgga
     2221 cagcggattt ccgatttatg caacggaaac catatcacac aaaaggaact tgcggagaag
     2281 ataggcgttt ccgcttccca gttgagccgc attgtcagcg gcgaaacgag aacggtcagc
     2341 agtgatattc tcataggtgt ggcaaaggaa tttaaggtat cgacagacta catactgggc
     2401 ttgtctaccg tgagcgtccg caaaagctac gatatttctg aattaggctt gtccgaggga
     2461 gccgtgaggg ggcttgtgac gggtgctgtt gatgtgcaaa tactcaatcg cttactggaa
     2521 cacaggaatt ttcccaagct gatagatttg atacggattt attttcagga cacggcggca
     2581 aaggggataa tggcacgaaa ccagcttatc gagatggcaa cggcttccct gtccgacctg
     2641 atgaaagaac acccggaaca ccgggcggaa gcaaagcagg atttacagct tttgaacgct
     2701 cagaagatgg gggaacatga agcggagata gagaaaatca aaaatgtgtt ccttgctatc
     2761 ctgcgggaca ttaagaaaga cattgacaac ggggaacagc cgggagaagc tgtgaccgcc
     2821 gctatgttcc aagccatgcg ggacactatg gcggagcaga aacaaaaccc gctttccatt
     2881 gacgatgtaa cagcgatgat agccggacag atcggacagc ttgcgccgat ggacaaagaa
     2941 actgccgacc tgttccagca gttggcgaag aagatgattg agcaggcagg aaaataaaac
     3001 ataaaattca aaggagatac ttatggcaac aaaaatattt gttcacggct caggacacaa
     3061 agcaacaagt tgggaaaaaa caatttcata catgacaaac aacgaagata ttgtatgtcc
     3121 aaatttatcc tccatccttg aagggaaaga ggcaagctac gaaaatctat attcttcatt
     3181 tgtaaaatat tgtaacgaat ttgacggaca aattcattta tgcggtcttt cattaggtgg
     3241 tattttggct ctgaattttg ctttggattt cccgcaaaaa gtgaaaacat tagttttaat
     3301 cggaacgcca tataaagtcc cgaaagtagc atttagtttt caaaatataa ttttcagatt
     3361 tttaccaaaa tctatttttg aaactatggc atttgataaa aagaacacat ttgctttagg
     3421 ggacactatg aagaatttag atttcagtga tagggtgaaa aatattaagt gccccacttt
     3481 aattctttgc ggaaagaaag acagtgcaaa tatgaaatca gcggattact tatcacaaag
     3541 tattagaagc gcagaattga aaattattga gaatacaggc catgttgtca atgaagaaaa
     3601 tccaaaagcc ttagcagata tattgaatga atactatttg aaaaattctt aaacaattct
     3661 gaaagaaact cgaaaactac aagcataaaa gtttagaaaa taaatagcaa agccagccga
     3721 gccagtcaat ggtcaagatg aacggcgcat ttcatgcgcc gccgttgaca gtcccgcccg
     3781 tctttgctaa agggtaatca aggcgggaaa gccctaaaat ggtttcacac ctatttcaat
     3841 aattggagga gataaaaatg agatcagaaa aggaagttta tgatattgtt ttgaattttg
     3901 caaaaacaga caaacgcatt cgcatggtta ctttggaagg atctagaaca aatacaaata
     3961 ttccgcctga tgattttcag gattttgata ttactttttt tgttacggat atggacagct
     4021 tcacaagtga tgataaatgg ctagatatat ttggtgaaag gttgattctg caaaagccgg
     4081 aagatatgga attatttcca gctgtagaaa agggattttc atatttaatg ctgtttactg
     4141 atgatgttaa gatagattta actttgctgc cgctggaact gatagacgag tattttacat
     4201 gggataaact ggtaaagtta ctgttggata aagacaaccg tatcgtaaag ccgccaatac
     4261 caacggatat agactaccac ttgcagaagc ctactcaaag aatgtttgac gattgctgta
     4321 atgaattttg gaatactaca acatatgtag taaagggctt atgccgcaaa gaaattcttt
     4381 ttgctattga ccatatgaat gatatagtac gaaaagaatt gcttcgcatg atttcctggc
     4441 tgattggtat caaacaggga tttcatttca gtttgggaaa aaactataaa tttatgaagc
     4501 aatatgtccc agaggaattg tgggaacgac ttatgtccac ttataatatg gattcctatc
     4561 cccatatgtg ggaatccttt gaacaatgta tggcattgtt ccgggaggtt tcgtcagaag
     4621 tggcatgcca gttggattac cagtatccac tatatgatga aaaaatcagt aattatgtga
     4681 ttcggcaaaa gaaaaaatat ggcattgaag atgataacaa ataaaatttt ttcaatcgaa
     4741 aaaatttatt ttgattattc aattttgaaa aactgaatac ctcaaaatca gaaagagcgc
     4801 ggacaagcac tttgagggat tggccgcctt gtccacccat tcagtgggac ggcgggtggc
     4861 ggtcaaggcc gggtgtaaac ccgttcattt cagccttgac ggttacccgc tgtcctgtta
     4921 cttttccggg agtgtagcca caacttcggg acactttgtc cacaagtcgg agcgtaggac
     4981 gagggacggg ggctttcata tacgccctgt ctgctgatga aaacagacct gcgcttgcgg
     5041 ctccacgcca cacaagcaca gccctgtttt cctgccgccc ctccccggcg gcaacggcat
     5101 tttcacggca acgccgacag agcgtataac acactaaagg gctatggtct tttcgttgat
     5161 ttcatcttgc atttaccgtc ctcctttcgc ggtagtctga tagtgttagg gtggtacgcc
     5221 gctgcggtag ccgcccataa gctttagata cggacgcgca agccgttcaa atcctcggcg
     5281 cggataccca caaggtacca ttcctgcgcc gcgctcattt caatgcgggt cggcttccat
     5341 ttgccgcctg tgaatacgtc gaaacactct ccgcaatgca agccgccgta atagtcggca
     5401 atgtcaaagc gaatgtcgta gcggtcggtc tgttcgtcaa aaatcaaagc tcctgttttc
     5461 tgtgccatgt ggtaatcctc ctttagattt tgcctgtcgc catgtcgtga gcgacaaggg
     5521 cggtatagta gctgtcaatg gtattcggcg cattgaacag caccgcttta aggtactgtt
     5581 tgatgttgcg gattttggtg gtattctctt tcatgcagtc aaagacaaat tcaatgtgac
     5641 tgctgttgag cttcataaac tttgccttga caagctctgc cgggtaatcg tccccggcga
     5701 tacggattgt ctttctcttg ctgcataccg tttcaaggat aatcgaaaca atttcgtcca
     5761 gacggtcttt gtctacctgc ccgtagcgta caaaatggtc gtactcgata ttgtccttga
     5821 tgatttcctc ataaacgctg tatgcgtctg tcgcttcctt tcgtttccgt tccggcggct
     5881 ctgccgcttc cccgtcgtaa ggcaagggat ttagggaatg gataggaatg gaatcggtac
     5941 ttgataaatc tatatttgat ttttcttttt tgggtaagtt agtcttttgt atatctttat
     6001 ttaattgcgt tggattttcc aacgtaggtt ttttctgcgt aggtttttcc aacgttggat
     6061 tatccaatgt tggattttcc aatgtaggta aatccgatac aggcggggtc tgcggctgct
     6121 caaaaatcac ataatctgcg ccgcgcaagc gtcctttctc gtcgcgttcc cttgaacgca
     6181 cgatataccc ggcgcgttcc agttccttaa cggcttcccg gatagcgtcg attttctccc
     6241 ggttgataaa ggacagcccc gcaagggtgt agtcccaatc ctctggcaag gacagcattt
     6301 gcgataacag cccttttgcc tttagggata gctccttatt gcgtaagtgg tggttgctca
     6361 taaccgtata gcccttgttg cgctccactc tgaaaactgc catagcttca tcactccttt
     6421 gctgcatacc tgttacgcaa tagaaacgcg attttgaggg tttaggtatc aatcccttat
     6481 ccgctgaaaa ccgcgtccgc aaagccgcgt aaatcaaggg ctttttcatg cctactgcgt
     6541 aacaaagggc atgaaaaaag cggcgttcct gttcttcctt gtgggaagtg agaaacgccg
     6601 cctgtgcggt gcgttattct gcttcttcgg ctatgaggtc ttgtatgact tcgccaaagt
     6661 ctgccgtaaa ggaaaaaatg aagtattcca aaacggcggg gtctgcgtcc ataggctcgg
     6721 cttcctcgga aaagggcaag cccataagcc catagagcat ttttatgatt ttgaacagct
     6781 tcccccggtc ggcgggggtg ttcatggtaa caagtacgtc ggtcaagcgg tttacggttt
     6841 ccatgtcgcc gcctgtcgtt acccatacca tttctgcgaa tggctgcgtg attgctccgg
     6901 ttacaaggtt taccttatcc ttgctgattt cgccggacgg gagtataata cccttgtcta
     6961 aaagtacgtt tttcatgtcg tcctcctata atttgtggtg ccaaaatggt gcccggtctt
     7021 acaaaatcat cttatacgga gatatggcaa gataaatgac gatatgcaga aaaccttgat
     7081 tttaagccat tttcgcgagg ttttataaac acttgcgcgg gcttataaga agatttccgt
     7141 ctatcaaatc aataaaaaat tacattttta ccaaatctgt ctataataac ccccgacaat
     7201 gtattatcaa ccagtaattt aactgtctgt tctttcccac cgaacattcc aaagctcttt
     7261 ttcgcataat cagccatatc catttttttt aaatgctctt ttccttctct attttcatct
     7321 aacaaagcaa tatgtagcat cttgtccaca cgaaaatgct taatcatact tgcctcagaa
     7381 tcatatccta tcaaataata gttttcatca tcccaggata atccccaagg gctaatatag
     7441 taatatgcgc caccatgccg caattccatt tcttttttta cattccattg gaaatactga
     7501 aatttaatct ttttgttctc tgtaatagca ttatgaattg catctactga ataataaata
     7561 ctctcattca ttgtttttat tcttccggaa acatacacct gtctctgcaa tttttgagca
     7621 tcatatttac ttaccagttt ttccaattta cgaatcagcg tatttgattt tttctccgta
     7681 atgaattttg atgactgaat tgcatcaacc agtaatttta attctgggag ttcaaaaggc
     7741 cggtttatga catggtaatg atatttattt ttaacaggtt caccttcaac ttcaatgcca
     7801 agaatttcta aatctttcaa gtccgcatac aagctttttc tgtcagctgt tattccatat
     7861 tcctcaagcg attcttttat ttctgacata gttatatagt gttcatcatc agtcttttcc
     7921 agcattattt ctgccagccg atataattta aatttttgat ttgatccttt gggcatagca
     7981 tacctctcct tcgcatatag caatagtata tcacacctgg gaattttatt gtacatgtta
     8041 ttcaagcaca catttccaat tctatatgca aaaaagccgg aagtagctat ataattatag
     8101 tacttccagc cccctgttac actgttctca gatctttacc aactcctctc tccggttcat
     8161 cttttccctg ttgtttagca ataatctcct tattgatttt caatcgctca tgaatagact
     8221 ttttcaccgg ctccaccggt ttcgcctttt cattcttacc agatgttatt gtcttccctg
     8281 cttccatttc agattttgat accgtggtcg attctactga tctctctggt gctctttctt
     8341 ccaaactgca gaaactctgc aaatacggca gcacatgctc ctgcatatct gtaagatcag
     8401 ctatatatgc ctgaaaggat tcttcaccct tacctttttg gtaattcagc cagctctcat
     8461 catgcatctt catttcattc tggttcttca actggctcac aataccgccg tttccatctc
     8521 cgatattgat tttccctttt agttcctgca tctggtcatg atctgggtag taaattgtaa
     8581 agtacatctg tacagttttc tccggcattc cagtctttga atctgcttgt gaagccagtt
     8641 ctgcatccat tttggctgtt atttcatcca gacttcccag cttctgataa cccgaaatat
     8701 ccatttcctt atcctcacag aaattgatgc ggacaaccgg tactgctgtt tccggtatct
     8761 caggctgata ggctttcagt ttctccagaa gttcttctgc ccggggagac tcttcgcatt
     8821 cctcatctat aatatctttc aaaaacggaa tgtacctatg ggcatagccg catcttaatt
     8881 ctaatgcgac agtttccacc atatcttcct ccgggctaaa gttatcatga taatcataat
     8941 ggtcaaagtc ttccgctaat tgatccagtg ctgcagccag ttcatccgca ttcattttct
     9001 ccggataata atgaacatcc aattcctttg gaggataata ccgaaaatcc ggaaatgctt
     9061 ctacaatctt ttccagtgct tcatgtacca ttggaagggc tgccaggaat gccacatcat
     9121 ccagactgtc tccccggatc gatttccggc tgaccaaaga tacctcagct tcatcataaa
     9181 aagtatcatt cgggtcacgg taaataatgc ccatgccatt tccatagtag cttaacgttg
     9241 ggtcatcaat gatttcccgg tattttgcaa atatctcatc cagatttgta ctcttatata
     9301 ttttgccaag actatggtat tcatcacatt ccgcagcata gtattccaga tacggctctt
     9361 tcttcggagg catattgttc aggacgttat cgatcatatt gtagtttgcc tcttccaact
     9421 cttctacttt cgccaatggc ttgtactccc ctctggcttt catctgctcc gttttttcat
     9481 ccagataccg ttcggatttt tcaagaaaat cttctaacgt accagtctta tccggtctga
     9541 tcgggttcat atctactctc atatttccga ccttataccc tgcttcattc aatgcagaaa
     9601 acaaatcatc ctcacgtaca gttccctcat aagcaattac cacatccaca tcagaatcct
     9661 gtttatatag cccatccctt gtacggcttc cgtacacacg cacagcctgt atcctggcat
     9721 ccaggtcatt ttcaataatc tctgcctgtg caatcgccca tatggtctct tcgatttctg
     9781 accggctcat tccatttaat ccagcttccg ctttgatata atctgaaata accggcacac
     9841 gctttctctg gcttcttact tcctgaagaa tctctgcctc cacttcttcc gctttttcct
     9901 gcaattcatc ataatctaca ggtatccgtt ctaactgttc cagtccctcg tcctctaaaa
     9961 tatcctgaat agcctgtctc atagaaatat ccggattctc caaaatgcct ccgtccatga
    10021 gcttatactc cttatcataa aaggaataat catatccctc cgttgccact tgaatagcaa
    10081 agtattgatc cccgatccgg taagccactt cctcctggtt cagttccggc tccaattgca
    10141 agaaatccgg caattcacgg aaactgatac tgtctacaaa ataggctttt acattcccat
    10201 tttcattgag gacaacaata tcactgaccg ataaagaatg cccggtataa tcttccggat
    10261 gggcaatatt gaacttttca tacagggaat ccaatgtatc gccataatgc atttcatcgg
    10321 agtagattaa ctcatagtcc tcttttttta cctgatatcc atgtctttca atgaaattca
    10381 gatccataaa ttcatatttt ctgccgggac tgccgtctat gatctggtat attccatatc
    10441 tgttttctgt ccccagaaga agtttcgcct cttttagtga cgttatctgc ggatactcct
    10501 gcatccgttt ctccaacgtc ctgatccgtt ccacatcttc tctctccatc tgataacgct
    10561 ccggtcctct ttcaatctcc atccgtttcc gcactgcaat cggccttgga taagtggtaa
    10621 tcaaatatac ggtctcccct gcatcgaaca tccttaatgc ttcgtttcta tccagatcta
    10681 tcattggggg ctgatataat ccagcttcct caaaatctat ttcgtcctcc tgctcctgca
    10741 tacgctgcca tgcctctttt tcaattccat agagaccttc atgttccaat atcatctccc
    10801 tgctggcata gtccccatga gtgccttctg actgcaggca gtacaccttt tccccgacac
    10861 gatgaagctc cagtgccatc tcctgacgaa ggggaaacat atcatctgcg gtataaccat
    10921 atccctttag ttctgccata ccaacggaac gatccgggaa ttcgtcaatt tcctctcttg
    10981 catccctcag aatttcatcc accttctctt catccgagga acgaacagca tctgcaaggt
    11041 ctctgatcat tttcctgata tcataatcat ccccagtcat agccgcatat tccagaacct
    11101 gttctttctg ttcctctgta aataaaatgt tttcccactg ttctgcccgt tccatctgtt
    11161 tctgggcata atcccgaact tctttttctg ccattgtcat attcctgttc attgccatat
    11221 gcctttcctc cctatgctcc aattcttctg gcaagtacaa tcagcctgcc gttggtgctg
    11281 gaatattcac aggtagataa agaaagcagc tcatcatcct ccctgacggt aacccccagc
    11341 ggataaagct gataagctgc cattttctgt aaataatcca tctgttgttt tcgtgtttct
    11401 ttgtgtaaaa aatcataata accaccgctt tgtgccacat tagtcacata cacagcagcc
    11461 acttcatact ggtatttctg gttttccaga tatagtgtga tctccttatg ctcatgataa
    11521 aactcttctt ttttatatcc attcaattgc ttgaacatac tgccatcttt catttggtga
    11581 ccataaataa tcaaatgttc ctgcccggca tctatatcat tccggcagtc cagcattaag
    11641 gttccacaga tggcataatt cttttgaaaa tcatggcgaa gataaaactc attgtcttct
    11701 ccctgcacga ccggataact gatatcggtt ccatcaatct tcagccaccc gatgcagtct
    11761 gcattttcat ccagcaaagc ctgataatca aaatcatcta tctctgtcat tggattatcc
    11821 gcattggaac cagtcccgtc ttcctctgta tccttttccg ggaatgctat ctcctccacc
    11881 tgacggtaat tctgcctgtt gtcataagaa tcctgccagt aatccaagag gtatttccca
    11941 catatcaacg taacaaccag aaacacaatc aacaatactt tctctgttct cttcacatag
    12001 cacctccttc cgggcatgaa aaaaccggca ggtatttcac tgccggtgta tatcggttat
    12061 aaaacataat tgaatttttt tacttttagt tccatcgtca ttaaatgttg attcagctct
    12121 aaaaactgaa atttgagtct ctgtaaaact ggaattaacc catacaatta ttttaattta
    12181 gatattcaca atattacttg ccacagtatc tcgaaaaaca ttatcatgtt ctaccaggag
    12241 catggtcggg gcaaactccg ttatgagctg ttcaatctgc atacgtgagt acacatcaat
    12301 aaagttgagc ggttcatccc atacatacaa gtgtgccttt tcacaaaggc ttttcgcaat
    12361 taggactttc ttcttttgcc cgccagaaaa gtctttaata tccttttcaa actgtatacg
    12421 ctcaaagtcc attttcctaa gaattgcctt gaacagactt tcatcaaggt tgttttcttc
    12481 tgcaaactcg gaaagggttc cacataaata cgatgtatcc tgtggcacat aagaaattac
    12541 aagcccagag ccaagtgtta ctgtacccgt ataatctatg gactgcccga ctaccaactt
    12601 taataggcta cttttgccac tgccgttctt cccgtcaagc acaatgcgtt ctccctgtct
    12661 tatttcaaac gaaacgggtt cacaaactga aatgccatca taacaaacta ctacattcga
    12721 taatgatgca atcaaatctg tatggtaatt aagcggttgt atcttgagtg cttctgcggt
    12781 ttccacattt ttcagcaatg ctgatttttg ttcgattgtc tgttgttgtc tcgcttctat
    12841 agattttgaa cgcttcatca ttttggcggc tttatgaccg acataacctt tatctgctgc
    12901 cccaattttg gaagcttcta cacgttcaga ccatactgca gagcgttttg ccgactgctg
    12961 taatcgtctg atgtcctttt gcaaacgttc gttctgagcc agttcaaatt cttgctgttg
    13021 ctcaaaattt gacatccatg atgaaaagtt tcctctttgc acttcgatat tcgctcggtt
    13081 aatcgataga atatggtcaa cacaatcgtc aagaaagcga cgatcgtgag aaactaagat
    13141 gaatcccttt ttctttttca gatatgtcgc cacacttttt ctcgctttgg catccaaatg
    13201 gttggtaggt tcatcaatca gtaggaaatg cccttcatta agaaaaagag cggcaagcaa
    13261 aacctttgtc tgctctccgt tggaaagtgt ttcaaaaggt cgccaaagca catcgacatc
    13321 aacatcaaga taagaaagtt ctcgcataag ttcccattct tccgcaagtg ggcaaacctc
    13381 ctgcaatata tcctctgtaa tacgattctt atctgaaacg ggataaggaa aataatcaaa
    13441 ctgtacggat gataggattt ttccgctata ctcatatttc ccaagcagaa gattcagaaa
    13501 ggttgtttta cctcgtccgt ttctgcccac aaaaccaagc ttccaatcgg tatcaacctg
    13561 gaaactgaca ttttcaaaaa cattatcata acttgtcgga tatgaaaacg taaggttttc
    13621 aattttaatc attgacataa atattatcct cctttgcgtg tcatacgata caaagtcggt
    13681 tcggtgaatg tttactccgt atagatttca ccaaaaggaa ccgacactat acggagtgaa
    13741 tcatgtgtaa ctatctgttc tgcactattc ataaagcacc tccaaaacaa aataagagcc
    13801 gcaagaaagt ttatccttgc agctcgtcat agcataataa caccactaag caaaagtggc
    13861 aacagcacta tattgagtaa gatagacata taactttctt gcaatagaca caataatgcc
    13921 aaagtatagc actaccgcat attttgattt tatttgcaag aaaagttaat catctttcca
    13981 cctctttcta aatttcaaaa cattatacca taaatcgcag gcaaatacaa gtggttacaa
    14041 gaatttaaca aatcgcttat aatacaatca tataacttta ctcattcctt actgaccgta
    14101 aaattcaaag tgaacaaaat cgctgcgcga tggcctgcca aggctgtggc gcagcttttt
    14161 actttttcca aaaaaggcag tgacaggatc gtcccaaaat agtattgtta aagcaccacc
    14221 aataacaaac ttcaaacacg ggcttagtcc caacaactgc ctatgaaaat gataccacct
    14281 tcaggctgct ttcacaagca gttttatttt gcaaatgctc ctccatgatg ggtagttact
    14341 gttgttatta ctacttttat ttcatggagg ttattttatg tacgaagata tttttgaatt
    14401 agtaactatt gctgcacaga aaaagaatct taaggaatcc actacaaagg cgtattgtca
    14461 cgcccttagc cctttcctga atgctaccgg taaaccctgg caggaactta ctgtagctga
    14521 tgcggatgat tacctgacca ccaaaagacg gatgggcatt ttacctgaaa cctacaacca
    14581 ttactatggt gctttacgct tcatgtacaa gcgggtactc aaactcaact gggacgaaga
    14641 tgaaattccc agaatgaaac gtgatcgttc cctgcctacg gttctatcaa gggaagaagt
    14701 gaatgccatt cttgatgtca ccacaaacct gaagtacaag gccatctttg ctgttatgta
    14761 ctcaggcggt cttcgggtat ctgaagcaac ccacttgcat tatgatgata tatctcgaag
    14821 caatcattcc attcacatcc gcaataccaa aaacagaatg gaccgataca ccattctggc
    14881 tgaccgcact ctcgacattc tgactcagta ctggtttcag tgccaaagac ccagaaatat
    14941 cctctttcca agtcagacaa ccggagaata tctggatatc tctgcggtaa accaagtatt
    15001 aagaagaagc tctgaacgag ccggaatccc taagcatgtc acttcccacg cattcaggca
    15061 cagcttcgcc agtcatcttc tggaagacgg atgtgatatt aaatatattc aggcattgtt
    15121 aggtcacttg gatcctaagt ctaccgagat ttatcttcat gtcagtaaca aaactttact
    15181 tggcattaaa agtccttttg atatacagga ggattcataa tgaagcatcc tactgtacag
    15241 gatatatttc tacggtttta tcctgaatac cttgataaat acaaaccttc ttcccagcaa
    15301 ttcaaagttg caaactgcat catcaactgc aaaaccggtg cttatggtgc caacgtaagc
    15361 atgtgtgagg actgtggcca cttgcaaatc cattataatt cctgccgtaa cagatgctgt
    15421 cccatgtgtc aggcactgcc aaaagaaatg tggattgaca aacgccgtga ggatgttctg
    15481 gatgctcctt actttcatgt ggtatttact gttccacaag aactcaattc tttaatctac
    15541 agcaaccagc agcttctata tgatgcaatg tatcattctg tttccgcaac tataaatgag
    15601 ctgaccgaag atacaaaata tctcggagca aagattggat atatttgcgt gttacatacc
    15661 tggggctctg aaatgaatta ccatccccat attcatgtca ttctactcgg tggtggtctg
    15721 acttccaaca atcaatggcg tgataaagga gaagaattct ttcttccggt aaaagtgtta
    15781 tcaaaactgt ttcggggtaa atatctggat gaactgaaaa acctctggga agagagaaaa
    15841 cttcagtttc acggaagcag tgaaaagtac cgcaaccatt atgctttcaa ggaactccta
    15901 aatacttgct atgaaaagga ttgggttccc cactgcaaga aaacctttaa tggtgcacag
    15961 tccgttatta actaccttgg gaaatacacc caccggattg ccatcagcaa ccatcgtatc
    16021 atccgcatgg atgaagatac agttacttac tatgtcaaag actaccgaga agaaggcaaa
    16081 tggaaggaat ttaccatttc cggtgttgaa tttattcgcc ggtttcttat gcatgtgcca
    16141 ccgaaacgct ttgtcagaat caggcattat ggattactat gcaccagaac caaaaccaga
    16201 catctgacat tatgtcggaa tctccttggc tgcaaacagt atctttcccg gctgaaagac
    16261 ctggatactc cacagatact cgaaaccctc tacggtataa aggttactgt ctgtaaacgc
    16321 tgtggcggac accttcgaaa accacaacag cggataccac tacgtattta aagcttagta
    16381 ttcatatttt ttgaaaagcc tcagaaatga ggtttatttg tcgtgcttag attcagaaac
    16441 gagctatctg ccacaatggc acaaccttta tcttatagta aagtgtaaag attgaaagtc
    16501 catacatagc ggctccggtg acgcgacttt gttcactata gaaaaatcga aattgatgta
    16561 aacgataggg cagtttatca aatattgtaa gctgctttat cgtttacacc aacttcgatt
    16621 ggtttctaat caagtttctg ttccctataa aataaattta tcgggattta ccaaatcgcc
    16681 aaacaacgat ttgttcattt aaaggggcat aaccccatgc ccctattcta caacattttt
    16741 ctcctgttgt atatccgaaa gattatccga tacacacttc tgatgttctc attgcaggct
    16801 ctttcccatc ctgtctctgg ctgttctgtt tgatagcagt aattctgtta tgaagagact
    16861 gatgttcttc tttctcctcg ccctgctctt cttccccctc caccacagtt tccttttcat
    16921 ccatgttcag caaggcattc agttccgaga gacgttccag tttctggttc agttcttcct
    16981 ctttcgggaa tggttttttc acctcttcca tcgcattttt cagctgtccc tgcaccgtct
    17041 caagcttacg ctctgcttcc gccagttttt gcgggattgc ctccaatgca ttattgatcc
    17101 tgatgatatt accgttttca tcggaaccaa ggctgacacg atatacgttt tcatttttca
    17161 gggaaaggat aaattcctta ttccaggaat caaactttaa gcggatggaa aatccctgat
    17221 actgtccgac attgatcatg gcatccgcct gtttcatgga ctggcagaca gcaagaaggg
    17281 ctgctcctgc ttcttttttc tcatagaata ctgtcccacc aacttccatc acaaatttct
    17341 ccggatccgt ggtcttattt gcctgatact gttccatatc cgctttgaat ccctcgatgc
    17401 tttccctaag tactgctatc tgctgtggga aattctttgc gatatcatct tccagccggt
    17461 aatggttgct cacaaaattc gctttcagca gtttcagctt cgatacttcc acatctagtg
    17521 ccattttttc cttaatcgcc ggattccccg ttgccagggc ttttacttcc gcataggaca
    17581 atgccgtatc gtctacatcc tcgcagcttc gtaccgggga tttgctggtc atgatctggg
    17641 aaatgaattt ctgcttgctt tcgatcagct gccacatgta actgtcgaag gttccttccg
    17701 tcacataccg atagatatgc actttcttgt tcctattgcc ctgacggatg atacgccctt
    17761 ccctttgttc cagatcagaa ggcttccatc ctacgtccag atgatgcagg gcaatcagac
    17821 ggtcctgcac gttggtaccg gcacccattt tagcggtaga acccagtaaa aaacgaacct
    17881 gtccggattt tactttactg aacagatccg ttttcttcac ttccgtattg gcatcatgaa
    17941 taaatgcgat ctctgcttcc ggcactcctt ttgccatgag tttctttttc aggtcatcat
    18001 aaacattgaa tgttccatcc cctttcggtg tgctgaggtc gcaaaaaatg agctgggcag
    18061 atcgttttga tgccgtctct ttccagatag caaagctctt ctccacacag gcacagattt
    18121 tactgtcccc atcatccgga agcaatggat tcacaagacg ctgatccagt gccagcttcc
    18181 ttccatcatt ggtcactttc agcatattgt caacagaaga atccacaccg ccgtcccgga
    18241 ttacttctgc acgttctcca aggctttcca cgatctcttt ctggtgctcg gatggtttta
    18301 aaaccaccgt ttcatattcc gcttccggca ccggaagttc cagctggtct gccgtcttaa
    18361 tatcggcaat ctccttaaac atactcataa gttccgggat attgtaaaac ctggcaaatc
    18421 tggattttgc ccggtatcca gtaccctccg gagccagttc gatactggtc acaacctcac
    18481 caaaggtgga tgcccaggaa tcaaaatgtc ccagtcccat ccggttcagt ttgccatact
    18541 gcaggtaacg ctgcatggta taaagttccg tcatgctgtt gctgaccggc gtgcccgttg
    18601 caaatgtaat gcctttcctg ccggtgattt catccagata ctggcatttg ttaaacatat
    18661 ctgccgattt ctgtgcttca ttctgggcaa tgcctgccac attcctcatt tttgtgtaaa
    18721 ggaatgcatt tttgtaataa tgagcttcat ccacatacag acggtctacc cccagttctt
    18781 caaacgttac cacatcatcc tttttctctt tgttctccag cttttccaga cgcctcctga
    18841 gactcttttt ggtcttttcc aactgtttta ccgtaaaacg gctgccatca ctttccagct
    18901 ttgcctgctg aattccttct tccagttctt cgatctgctc ttcgatgatc tttttctggc
    18961 gttcttccga taaggggatc ctctcaaact gggaatgccc gatgatcact gcgtcatagc
    19021 tgcccattgc gattctggca cagaactttt tacggtttga cggttcaaaa tcttttttcg
    19081 ttgccaccag gatattggct cccggataaa gctgtagaaa ctctgcgccc cactgctccg
    19141 tcaggtggtt gggaactaca aaaaggcttt tctgggcaat accaagacgt ttgctctcca
    19201 tagctgcagc taccatctca taggtctttc cgcttcccac gacatgggca agcaggacat
    19261 tatccccata aagctgatgg gcaacggcat ttttctggtg cggacgaagc tctatttccg
    19321 gattcattcc cggaaaggtc agatggcttc catcgtattc cctgggacgg atggaattga
    19381 aacgttcatt ataaatccgg cacagctttt ccctctgttc ctgatccctg aagatccagt
    19441 ccttaaatgc ttccttgatc gcatcctgtt tctgggttgc cagcatcgtt tcttttttat
    19501 tcaacacacg gatttcattt ccctctgcat ccagctttgt gtcataaatc cgtacgtctt
    19561 ttaaattcag ggtttcttcc agaatcttat aggcattgat ccggctggta ccatacgttg
    19621 ctgtggtcag cacattccgg tcactgtccg catttttacc gctgatattc catgcaccac
    19681 tggcttccga ataccggata tcaattaccc ttccaaccag ataccccggg gtatcaaata
    19741 gttctaccat aaaatcccgg tatatttccg gggcgatcca tgtggcaccg atccggactt
    19801 caatctctga tgcatccagg tctaccggct gcacctgctt aagggcattt acattgctgg
    19861 taaattccgg gtggttttct gcaaagattc ttgccatttt cagcttctcc cggacattcc
    19921 cggatagata ttcatccgca gtctcccact gtccattgac cggatcccga aagattactc
    19981 ctgtcagttc ttctgcaact ttctcttccg tcttacctgt cagccctgcc atataaggaa
    20041 gatcaaccct tgctttttca ttcagggaaa tcgtcagggc ttccgccgca gtttccacac
    20101 tggtcacagc cactgctttc ttgatcgtcc gcttggtaaa catatccgct ttccgcttta
    20161 acgtaccatc ttcgttaagt tcctccaacg aacagagcag acaataagaa gagtcatcgg
    20221 agaatgcccg tttgtttgca ttgcttccga tgaccccgta tttttccgtg taggcgtcat
    20281 agacctgatt cagtttgacc tgaagctcct gtatcgcctc atttgttgca ttttcctcca
    20341 tctgcagggc gatcaactcc cggaccacct cacggatctc taccataccc tttacacgtt
    20401 ccgccgtggt tgccggcagc ttcaccggat tcatcaggga atttacccgg taatagatct
    20461 ggtcatccac cacggtaaaa ctgtagttcc ggacagacgg atctgccgga atgctctcca
    20521 tgatctcatc cagttctgtt tctgccgtta ctgcaggaac catcgttcca tggatttttg
    20581 caacagcatc ttccagctgt tctgccaggt ctgccccttc cagcggaaga caggcagtct
    20641 ccatgccata aggtccggac acctctgcca tcgttccaag taccatttcc gggtgggtaa
    20701 taaaataccg gtttatgcta attccattta catcctctcc aagagtaacc cattccggct
    20761 cttccatgga aatgctctcc ctcttctgga aaaacagaat gtcggcactg acttcggttc
    20821 ctgcattcgc cttaaaagca ttgttcggaa gacggatcgc accgagaagc tctgccctct
    20881 ctgcaagata cttccttact tccggcgatg ctttatccat ggttcccttg gttgtgatca
    20941 gggcagccac gccacccggt cgtaactggt caatggtttt tgcaaggaaa taatcatgga
    21001 ccataaaatg atacttgtca tactggcggt cattcacttt ataggaacca aaagggacat
    21061 tcccgattgc cacatcaaaa aaatcattgg gataatcggt cttttcaaat cctttgatct
    21121 ggatatcagc gttcggataa agcagttttg cgatcctgcc gctgatgctg tccagttcca
    21181 ctccataaag ccgggactgc tgtaacttgt ccggaagcat tccaaaaaag tttcctacac
    21241 ccatggatgg ttccaggatg tttccctttt caaatcccag attctgaagc aactgataca
    21301 tgctctcgat gataacaggc tgtgtataat gggcattcaa cgtggattcc cttgccgccg
    21361 catactcctc tttggtaagc agatctttca gttcctgata ctcctcactc caggaggctt
    21421 tgctttcatc aaaagcatcc ggcaagcctc cccagccaac atagtttgac aggatttcct
    21481 gttcctctgg tgatgcataa cggttctcgc tttcacattt tttcaaaaca cggattgcca
    21541 tcacattggc tctgaatttt tcctttgctg ttccatagcc cagctggtca tccgtgatat
    21601 gaaaattgac aggcggtatc tcaacagaca attcccgttc tctttgccca tactcactcc
    21661 agacacgttc cgatatttgc cggaaataga tggattcatt ttccatgata ctgtattgga
    21721 cttcccgaag ttcttccagg ttcgccgcat tttcaatatc ctcatgatac tgaaaatata
    21781 gtgcttcccg ttccagtacc ctctccagcc gttccagttc cggctcagac attctttccc
    21841 agatatcatc tttttccgta tggatggtaa acccttcccc gtcatcgtgg tattccacca
    21901 tataatgcag gatatcctgc tccccacgga tctcacaggt aaagtcatac tccgtcgtcc
    21961 tgctcacaga ggaatactgg cggtttacta agaccaggtt ctgcacatct tctgccctta
    22021 atggctgccc gctttcttcc ggcttatctt ccacattttc ttccgcatga acttcctcaa
    22081 cctcttccga aacttcctct gttcccagtg actgctttac ctcttccata tcagcaagcc
    22141 gctgggcttc ctgccgttct tcatactttt ccagttcttc cggtgacaaa aaatcatcca
    22201 tccggatcag ctgcctcgtc ctggaagctg cctgtttcca cttgaccagt gttgtcaggc
    22261 ttgggttgga tatctgtcct ttgcttaaac gaatcccttt tgcgtcatgc cactcatcgg
    22321 aaaggtcgct tccctggatt cccggtgtgc atcctccgtc tccatactca tgttttaaga
    22381 agtcggctgc ttctttttca tcgtggtgtt ccatgaaaaa ctcatagata cggctcctac
    22441 cgccagctac atttccaccc ctccgtaaaa cagagtcaat ctcatcctgc gtaataaaag
    22501 ccatttccgg cggtattatg atttcttcct gccgactcca atcaagcgtc cttccaaggt
    22561 cataaaccct ctgcttgtat atcggattat tccggatctg gtacctcata tagttttccg
    22621 gatgacgttc catatcccgc tccagttcct caagcatctg gtaatactcc cttgtctgct
    22681 tcggatcatc cagacctgca cggaaccttt cagtcgtttc tgtatggctg tatattcccc
    22741 tgatagcccc ggtatcccgg aaatgcagtg ccagctggct ggaaagctca tcacattcca
    22801 ctttaatgga attttgcata atcacgttgg aaacataagt ccccgcatca tacatatcct
    22861 gaatacggtt tgccgcttct tcccaggtaa gcatacggtc ataattgtgt cttgcggatt
    22921 ccccacgtcg gaaacgcata ccgtccccgt cataccagac gctgaatttc tgtccggaaa
    22981 actcaaaccc tttcccgccg gtaccatatt cctggatgag aaaacttctc agtttctcat
    23041 ggtcaattcc ttccacaagt tttgcagtga tatggaataa tgtattcttc cgtccgcttc
    23101 cggtacgaag cacatcatcc acgatctcat ccgaaacaaa aaaagcggct ggctgtgtga
    23161 gtgcagctgc cgctttcctg atctctccaa actgttcttc ctctgtgggg aacaggctta
    23221 attgtatata atctcctgaa ccaccatctc ctctgcctgt gcgcggatct ggttcatgtg
    23281 acgggtccat gccatgctgt cggctgattt ctccggtgcc ggggctttct ccagaagctg
    23341 catggtcagg tcttccactt tctgtctggc ttcgctgtcc actttcatca gatggctgtc
    23401 cagcctgttc tgcagtgcca gtatgctgaa tctggctttc ttgtggttcc tcagatattc
    23461 cttccgcatc atcccgtatt tcccgatggt tcccctggtc tcctccagtt tgatatccgg
    23521 gatcagataa tccccgttcc tgctgtaagt gatctctctc atgctctgtt acctccttgt
    23581 tttcttctat ctctggttct ggtgtaattt ctccactttc acgaattaac gtgttaaatt
    23641 cattatagac cacttccgat tcttttgcaa ccgttttcct gtcattttcc agatccataa
    23701 ggacataccg tccaagctgc atcagaatcg gtctgcagat ctcattaacc gctgtgccaa
    23761 ggtgcccaag cacacggaga tcattaaaat ctgtgatgtg ccgcaggctg tccacagaca
    23821 gatactcttc cgtatccatc ccacaccgct ttaacaggac ataccataca ctgtccgtca
    23881 taaggtcccg gaactccact tcctggttct gctcatccag ttcttccaga aatgtcccct
    23941 gcacatcctg tttcagttca tcaaacgcat ccggaagcca ctcccgcaca ctttcctgtg
    24001 ctgcctgatg cagggttccg gcaagcccgc catctccttc gtccaatcca tacgctctct
    24061 gcagataatc tgccgcaaga aaacggtcat cctgtggcag cacccacaaa gccgggtctt
    24121 tccccagatt ccgaacctta taagtatccg aaatatcaaa cacataccgc aggcggtttt
    24181 tcgggctgga tgtataatca atcagggcaa tgcctttcga gcctttcctg atccatcggt
    24241 acatccgctt attccatacc tccatggatg ccacagcggt tgcttccggt ctctgggcaa
    24301 agatcaggag ctgttcatca aaggtgtatt tatataaccg ggatgcggta tccagaaaac
    24361 gcatccactc ttccggcttt gctgcgatgt cctttgcgac ttcttccgtc agctgttcca
    24421 tggcatacaa tttatttgcc atatctgttc atcctcctct cattctattg tcgtttcccg
    24481 ttttttcttc acaccggatg ttttctgacc ggatgtgatc tttttccggt tttcctccag
    24541 ggattccttg attgattttt tatgtggttt ctcatatcca taattctctg cttccttttc
    24601 tgctactttc agattgatat cattcaaatc cacagagtat tgaatctgct ccataggaag
    24661 gatctgtttt tcccggaaag aaaaatagga ctggtcattt ccaagaatca catggtcaat
    24721 cacaggaatc ccagccagca tacaaagctg ctgcatcctg cctgtaagtg caatgtcctc
    24781 cttcgagggt ttcaggctgc cgcttggatg gttgtggaac aaaagaatgg aagcggcatt
    24841 cgataagaac gccgctttta atacttccct cggatgcacc agtgactggt tcagtgtccc
    24901 catactgatg atggtcatgt taatgggaac attgtcactc cgaagatgaa ccactcctac
    24961 cacctcccgg tcatagtctt taaaggtatc tcccaatacc cggatcgcat cttccggtgt
    25021 agagatctct ttctcactca ggatcggtgc ttcttttaca agccgaaccg atacctggtc
    25081 aattccgtat tttcttctca ctttctgatg ctcccctctt taagggaatt tgaagaatga
    25141 actcctggtc tttttgtgac tccaggcatt tccggagata tccggataac ctttttcttt
    25201 cttccttttt cattttgctg ctcattcccc ttctccctcc acgacctctt ccataacatc
    25261 tgcaatccgt tccaattccc ttacaaggga agggaactca taactgttcc tggcttttcc
    25321 aatctgatcc agtaaaaatt ccggtacatt gttgattgcc tgcgctatca atacttttac
    25381 ccttaaatcc tgaatagtca gaagttcttt gagtccaaat tcttcaccca aaacttcctt
    25441 atacctgatt aactcgcctt caaggctatc cggttctaac cgtctttcaa acttttctct
    25501 tatatcatca ccatataagc accactctga catatacatc ctccttcata taagggaacc
    25561 tccacaatgg aagtcccctt ataactctgc ttattattgt tacattacca tagccgtatc
    25621 tctcgtttta ccctgtggct ttaccaggac atccccggct ttcatctctt ccttcgcctt
    25681 ttccagcttc ccatgaatcc cggttttctc tgccggcttt tctgccgcag ccgctttttc
    25741 tttttccaga cgtgcttccc gtttctccgc attttccatc acggctgttc tgccatcaca
    25801 aaactgcact ttatccgaaa gaatatcttc cagtgctact tctgttgcat tgacttcttt
    25861 taccatggca ttcagggctt tcacatcgaa atctccatta tccggcaaaa gaagtgtttc
    25921 atggatggaa gaaggcagga tataaaaatc acccttcata aactccccga tctgttttcg
    25981 gatatcctca tgcaggatca gggatgccgc attcattttt gtttcgttcg tcaggcaaaa
    26041 cataggcatg aaaaattcct ctgcccttct ttctccgttc aacaggttct ggggtttttc
    26101 tcccataatc gaggattcca tcagatcatt tattgcgtat aaagccggtc cacggttctt
    26161 atctgatgcc atcgcatcct gatggagcgt ctggacatca atcttccacg cctctaaaag
    26221 tgctttggtc acggaaacag aagcaatgcc gtctttattt tccgacaggt tgaccgtata
    26281 ataagctgcg aaatccccat gcatggtcac agctttatct tccagccatt ccctgttctt
    26341 ttccgggtca cacatcctga cctgcagctt atccttgaca ttcccgtaat ccatcatgcc
    26401 atttacatca acgtccaggt ccgtatccat tttttcaatc caaaggtctg ccacatcccc
    26461 tacacaggca tccggacttt tcccgttccg gtattcctgg taaaaggaat ccagatatac
    26521 attcggtgtg atattggtgt cctttgcggg aatgaccacc gccgtcagtg tcagcccgtt
    26581 cttctttact acttcctgca gatggatatt ggcatccgca tatttttccg gaagatagtc
    26641 cttcacattg tccttcacat attcaaaaaa atcttttctg ttcatcatac gcaattaccc
    26701 ccttctgatc atgtgctggt tcattctctt tttgttgact gcctgctctg cttttttctg
    26761 gtatgccatc attctcttga atgatctctc ctgcatttct ctccctgcct gcactgtgtt
    26821 cattgttttc ttcatattct ttacctgtcc tttcttgatt ttgctatgat aaaagggagc
    26881 ctcaaatcaa gactccctgc tcatataagg tttctatttt ctttttctct ttcttctgtc
    26941 tgccagaagt ccggcaatgc cgcttacaga tactgccagc agtaccaccg gaatccagag
    27001 attcgtctca tcaccggtct tcggattatc tgctgacggt gttcccggcg taccttccgt
    27061 tgtctgtggc acttccggct tgtcatttgt caggtcaaag gtcacttcca caatcggtgt
    27121 gctgtcatct ttgtaggcaa ataccacctc atgctcggtc tcatccagtg tgtatccatc
    27181 cagtgtcttg gtttctacca gataatattt cttctcaccg gcaaatttac cgtctttgta
    27241 ctcagcgatc tcataaaggc tgctctccgc atgaccggca gcatccgtct ttaaggtctc
    27301 cagcaccttt cccttgctgt cacggagttc aaattccacg ccttttaacg gctcgccggt
    27361 ttccttatct gttttattca ggatcacttt accctttgcg gtatcatcct tcataacaac
    27421 cgtctggatc tcaccggtat ctttcacttc aaaggagaca tctgctgtca ggataaatcc
    27481 tttcggtgcc tgttcctccc tgagtgtgta tctgccaatc ggcagcttct ccacataatg
    27541 cggctcctct gtggaagtcc agctttccac tacctggtca ttttcatcca ggatcgtaag
    27601 cttagcaccc ggaatctcct ggtctccggt gatatctgtc ttgctgatct gtacctttgt
    27661 cacatcgtcc ttcatttcat gcttctggat ttccgcagta ttctcgatgg taaattcgat
    27721 gctttctgcg gttacatatc catctgcagg tttggtttct gtcattgtgt aggttttgcc
    27781 gactaccagc tctttgatca catgggcttc ttctgtggat acccattcat ccaccacatt
    27841 gccgtcctca tcggtcactt tcaggtgggc accgggaagc tcatcccctg ttgtcaggac
    27901 agattttgtc agttccacgg ttgtagcctc attttcaaag gtaaaatcat agcttacctc
    27961 tgcctgatcc gcaccagcat attcaaagat gaaatcctgt tcctcattgg tggtcacaaa
    28021 accatccgga gcatacagct ctttcacata atagtttccg tctaccggca ggtctgccgt
    28081 aaaggtaatc tgaccgtttt catccgtggt cttaagctca atgagcgtat ctgcttccag
    28141 caggacatca ccgctggcat ttttgatatc ctcccttgta aacaatccga agataccgcc
    28201 tgccagtaca cgctccgtgt ctttttcctt tttcaggacg gtcactttga ctttctggcg
    28261 gttgttctgc catgcttcat catacgttac caccggggta tcctggtcac ggtaacttaa
    28321 atccacatat cttggctccc catccagcac ataaccatgg gcagtttctg cctctttcac
    28381 atagtatttt ccaaccggaa gatccccaag ctgtgcaata ccattggtat cggtggtaat
    28441 ggttcccacc agttcatctg ctttaaaata atcctcgctg acaccatctg ccgctttgat
    28501 atcttcagcg gcataaacgt gaaaagtaac ttcggtaagg cttccggtga tatactcaaa
    28561 cagatgctcc accgtgcctt ttgcattatc cagaagcgtt actttatcca ggaattcacc
    28621 ctttttgttg atgatcagaa gcccggtcgg cacttcatcc ttcatttcaa ccttctggac
    28681 atcaccgtta tcctcaacag taaacgtgat atccgttgct ttcaggtatc catacggggc
    28741 aaattcttcc cggagtgtgt aagtctcccc gactaccaga cgtttgatca catgtggggc
    28801 atccttaaca gaagtccatt catccacaac attcccatct ttatccagca ctttcaggct
    28861 tgcaccatcc agttctgttc cagtagtaat gtcagatttt gtgatttcca ctgtggtcgg
    28921 ctggtttttc ttcacggctt tcaaaacaac cgtttccaca tcctgtcctt gataggaagc
    28981 atcaaagttc agaacctcat tggaagatac ataacctgcc ggggctttca gttctttcac
    29041 atagtagctt ccaagcggaa gatccagtgt acagcctgcc tgtcccttct catccgaagt
    29101 catttcctga agaagggtat ctgcctcaac aattactttg ccgtctgcgg taatatcctc
    29161 tttgttgtag ataccaaata cggcacctgc cacaacagca ccattttccg catcctgttt
    29221 ttcaaccgta atcgctacct tctgtctttc atcaccgacc gtcacttcct gttctaccac
    29281 cggagtatcc tgaccttcat agacaaagac aacttctgca gcctccggat ttaacacaaa
    29341 tccgtcaggg gctgtttttt ccactacccg gtaagcacca agcggaaggt tttctgccac
    29401 tgccattcca tcatcaccgg ttgtgatcgt agtcaccagt gtattctttg catagactac
    29461 aatccgtttt ccatctgcgt ctttctggta gtccgtggag taaatatcct ccgctgcata
    29521 cacctcaaag acggcatctt tcaggaactg ctcttcgtaa ataaaatcct tgttaaatcc
    29581 agcaagcatc tcaccttttt tgtaaacagt cagctttcct ttgaccggat ggttttcgta
    29641 atctacttca atcaccacat ccccgctgac agaatccatc tggtatgccg tattggaatc
    29701 cactgcgatc tccacgtaat tctggtttaa ggtatagcca tccggggctg tcacttcctc
    29761 gatccggtaa tgtccgatgc ttaaattgtt cggaagaatc agataaccct ggctgtccgt
    29821 gaagtaggat ttgtgggtaa cagtggtcgg gtaagtcgta acctgttcca catatttctt
    29881 atggtccagg tcataaatct taaattctgt acctgccacc agcaccggtc tctttgtttc
    29941 atcgtctttc ttcacgatct ttaactttgc tttaaattca tcatccagaa ggatccgcca
    30001 gatctgcggc tcatccggat ggttttcact gatggtaaca aggaaatcat ccaccggctt
    30061 ataattgtgc ggggttgttg tttcctttac aaggtaagta ccatacggaa gcgggatgct
    30121 gcaggcataa cctttggcat cggtaaacat ctctgtcttt ccatctgcgg tcagtactac
    30181 cggcttggca gatgcaaaat cgtaactgcc gtccggattg gtcttaaggc tgctctttaa
    30241 gtaagcagta aatccggcac cttttaacag gtctgcgtct gtctttccat tgttcgccgc
    30301 tttaatcacc tggaacggct gtttcatgac ctgttccgaa gattccgtac tgcgctccac
    30361 agtttttaca aggtctccct cataactgca ttccaggtca tactcaccct cgtcgatcag
    30421 gtatccaatc ggcggtgtga tctctttcac atagtatttt ccaaggtaca ggtctactac
    30481 agaagcatca ccctttttat caaccgtcat ggttgccacc tggcttcctg ctttatagag
    30541 gatgccggtt tttccatccg gatggatgat gttttctctg gcatacactc cataaacagc
    30601 gccttcaaag gcggcgtctc cctgggtgtt tcttccggtc tctttatctt tcttgaccag
    30661 atggatcgtc gcattgacac gttcattttc aaacgtatgg gtaaatgcga cggatgcctg
    30721 tttatcattg gtgtactgaa atctgaaaga gaatacatcc tcactatttc ggaaataatt
    30781 tgccggtgcc tgcagctctt tcacataata gctgtggttg atcggcaggt ctgcctggta
    30841 tacggcattg ccatcggttc cggttgttgc tttttcaatc agggtatctt ttcccaccac
    30901 aacattcccg gatacgtcag cgatattctc tgccgcatac agtccgtaaa ttcctccgga
    30961 cagcgggttc tttgtggtat catcctgttt caccacagat acgcttgcct tctggcggtc
    31021 attggcaaag gtcacatttc ctactgccac ttccacgttc tgccctgcat agcttaaggt
    31081 gacggttttg gattcccctt tgcacacata atctgccggg gctttcgttt ctgttacaac
    31141 gtaagtgcca agatgcaggt tcttaagggt tgcactgcca tcctcaccgg tggtcagccc
    31201 ctcttttacc agggcaccct tttggaaaat aacccttcca tctgccgctt tgatatccgc
    31261 tccggcatac acgttataaa cagcgccttt caatctctgt tttgtgtact ggaacaccac
    31321 gccggaatct gtgacagaag caccggtcag cacttcccct tccttataaa cggtcaggtc
    31381 tgcaaactgt tccttatcag ttacgtcttt ctttgtagtc ccgccgatga ccaggttgat
    31441 cccataggct ttggtatcca gcacatagcc attcggtacg gaaatctctt tcaggtacac
    31501 ggtattctgt gtcttttcaa tcgtgatact ggatgcacca ttggcatcgg ttgcaggcat
    31561 ctttgcgatc aggtttttcc ctgcttcatc actgtaaatg ccatagactg caccggctac
    31621 cttcgcattg cttccggcat ccttctttac gatctcaatc tttgccatct tgacccattc
    31681 cacactgaaa tctacatact tctcatctgt gacaccttct ccaaatacca gtgccaggtc
    31741 ctgtgtagat gaccctgtgg tgatcttata agcggaataa tccttggtaa tgcttccttt
    31801 catggtcact gcccaggaac cgctgacatc ttccgcctgt gtcagaggtg cggaaagata
    31861 aaactttgtg ccgccggata cttctacgct tgcccctgcc gcactggtct ttccggttga
    31921 aacgttgtgg aatttcacgc cggatggaag cttcatcgta atggtctgaa gcgcatctgc
    31981 cttaaaagtg atctcttccg ttctctggga attgccgtca atataggctt ttaccttcgc
    32041 attggaaaat gacatcgcca cgtccgggat ctccggctgg ctcacacagt agttatagag
    32101 ttccatggcc agcgcctgtc cggtggagtt ggtgccggaa aaggcatcac tgcttccatt
    32161 tgcataagcg gctgccagat gggtaatgat aaaacgcttt ccggtagaaa aatccggatg
    32221 cttttctgcg aaaaatcctt catccccgct ggcttttgta ccgtagtagc agactttcgc
    32281 taaagtcttt ccgtcactga gctttgtgat cgtataagtt ccatcccctg gccccggctt
    32341 ggatggctgt acgcaatagg cagtagcagt aacatcacca aactttacgg tataaggtgc
    32401 ggtcaggtaa gaacccagac cataatctgc ataataataa tatgcccctc tggttacact
    32461 gacggaggtc gtggatctgg cacttgcaaa cagtgcctgt gcctgaaact gtaccgtctc
    32521 gccttcttcc aggctcagca tatcaattcc ctgttcttcg ccctgttcca gtacatcaga
    32581 tacggaaagc ccggtctccg agtcaacggt ttcctgccct tcgctttcct ccagtgctgc
    32641 atccagttcc tcttccggaa gaacttcggt gctttctact gtttccgttt ctggttcagc
    32701 ctctgtgact ggttctgtgg cagcttccgt ctccatggac gtttctgttg tttcactctc
    32761 ttctgcagaa aacgtctgcg agtctgcctc cccatcatct gccgcttcct ctgtaccgcc
    32821 ggaaccggca tcttcgccgc ctccttctga agcagcctgc acttcagttt ccgcctcttt
    32881 tacgatcagg tttctgctga tctggtactt cggatgtgct tcattgaccg gctccacata
    32941 gtagacggct ttataactgt ctgcgtggtc taaagcaaaa tcctttccct cttcattctt
    33001 agcttcctca aaagtgactt ttactttttt gtcatctttg atctccagcc cggtaaaatc
    33061 acaggtgacg tcaaattcac ttccaacagt aatttcaaaa tccttggctt ttaccacttc
    33121 atcttcgtcc agcagatcct tgacctcttc ataaaggggc ggcttttctt ccgctttggg
    33181 ttctgccgca taggctgtca tgggcgataa caccgtggat aacatcgtca gccctgccag
    33241 aaatccggat acgagtctcc ttaaatgtcc tgttcttctc atagatcatg tcctctcttt
    33301 cattttttat atgaaaacag acagcctttt agctgcctgg ttcctaacta ccgctggggg
    33361 aaatgcaggt taaactgtgc ttttccctca ctgtcagcta ccatttctac ggtagcttca
    33421 taacttttcc cggttctttt cgataccagg tctttgtaat ggactttgcc tttcttcagg
    33481 aatttttttg ccgttgcttt atccatcttc ttcccctggc ttgcaaggaa atggtcatcc
    33541 ttccacaaag aaaagcggca ttcctgcccg gtacagtaat aattcttttt accttccctc
    33601 acatcactgc cgcagaccgg acatttcccg atcacttctc ccattgctgt tcccggaaaa
    33661 cggctgcttt cctcctcaga aatcgaatgg taacgggaaa tcagttctcc cagcatatcc
    33721 gtgatcccat ttaagaaatg ctctgccgtc tctgtcccct gtgcgatatg gtttaatgcc
    33781 atctcccact ctgctgtcat cttcggggac ttgatctcat ccggaaggac tgtgaccagt
    33841 acattccccg catctgtcgg caccagattc ttcttttccc tttttacaaa gccggactgg
    33901 atgagttttt caatgatccc ggctctcgtt gccggtgtac caagcccctt cttttccgta
    33961 tcctctgtca gttcttcatt gcctgcccgc tccatcgccg ccagaagcgt gtcttccgta
    34021 tactggcggg gcggctgggt aaagttttct gaaacagaag tgctgcacgg accgatattc
    34081 cttccaaggt aaaggtcaaa ttccgcttcc tgttccggtt ccctgacacc taaaaactgt
    34141 ttcagtttct tctctatcgc ctggaaccct tcctgttttg tcttccttgc attgaaataa
    34201 aacgtatgga agttgcaggt cagctggcac ttatgggtct cataaatata gggatccgcc
    34261 gttgcggtga gtaccctggc actgatcaga tacagaatgt tcctctcctt ttctttcagc
    34321 ttctgaaggt ctgctttctc cacttccgaa gtggggataa ttgcatgatg gtctgatacc
    34381 tttttagagt tcagtacttt agaaatatcc ggttcatacg caatcccctc tgcgaaaggc
    34441 atcctggata acagcaactg aataagctgt ttcgtactgt tccccatctc atccgtcaga
    34501 tactggctgt ctgtcctggg atacgtcacc agcttctttt catacatctc ctgaacagaa
    34561 tccaacgtct gctgtgccgt gtaaccaaag atacggttgg catccctctg gagagaagtc
    34621 aggtcataca gtttcggtgc ccgcacggtt ttcgtctgca catcttcttt ctccacctgg
    34681 cacatgcgtt cgctgcagtc ggcagccacc tgatccgctt cttccttttt ctggaaatgc
    34741 tcagagacag catcaaactc cccgaatgtt aagtgggcta catagtattt ttcttttaca
    34801 aactccttca ccttctggtt cctgtccacg atcatggcaa gagtcggggt ctgcaccctg
    34861 cccactttca ggttctggtt gtaaaggacg gaaaaaagac ggctcgcatt gattcccacc
    34921 agccagtctg cttttgccct gcataaggct gactgataaa ggtcttcata acacgaaccg
    34981 tctttcaacg atgcaaaccc ttctttaatt gcacgttctt ccatggatga gatccagagc
    35041 cttttgaccg gctttttgca tcctgcctgc tcatagacaa aacggaagat cagttcccct
    35101 tcccttccgg catctgtggc acagatgacc tcatccactt ctttgctgtt catcagtttc
    35161 tttaaaatct ggaactgctt ctttgtcccg tcaaggactt tccttttcca ttcttccggt
    35221 atgatcggga ggtcttcata tctccatttt ttataacgtt catcatattc cgatgcgtca
    35281 cagaatgcta ccagatgccc gacacaccac gaaaccagat actcctttcc ctccacatat
    35341 ccatctttcc gttcccttgc tccgaccacc tttgccagag ccatcgcaac agacggcttt
    35401 tctgctatta ctaacttcat ctcactcatc ctttctgctt tccatatcaa tatcggattc
    35461 tacttcattc ccccagacat cccatccggg cgtcttctgc ctggcaaaca gctcaatgcg
    35521 gggcacatca cccatcagct gcacgatcct ctcccttgct tcctgcggct ttttgctgtg
    35581 ttcctcgatg tgggatacaa tcacctgatg gactccggca gactgccgtt tcggtgaacc
    35641 tctggttgcc aggatacaga attcggcatt gctccttgtc cagtaaccca ttccccagaa
    35701 caggctgtcc gctttcttat tctgcttgat ccagacaaaa gcaatggtct tatactggaa
    35761 tccccaggcc tgcaggacgg aaagcccttc cagcaggcac gggatcgtca cccacaaaaa
    35821 cagggcacaa tccttttctg ccagctccgc caccggcagg gcacggatct catcaatccc
    35881 cattgtgggg taatggctct ctgcactccg ccctaatcct tttttggaat acacacggta
    35941 ctgccacggc ggatctgcat agataaccgg atattttttc atctgcatca aaacacccca
    36001 ttatgattcc tcctcatctt ccaggacttc ctctggatcc tcttcatccg gaagtgtctc
    36061 ttcttccgca tcatccggtt ccgcaggttc ttccgcttct tcggactcat catcctcata
    36121 ttcatcctca tcatcgtatt catgcttcgg cttatagacc ttgaagtaat atccggcacc
    36181 caacgcaccg gcagctgcca gcccgatcaa aagataggaa ccaaccgggg atttatcctc
    36241 cggcatctgc acttcctctg tttcctgctc ttcctcttcc ggctcctgcg tcggctccgg
    36301 ttcctctgtt tccggttctg catacacagt atctacctcc ggaagcgtta ccgtatcgga
    36361 aagtgtgaag ttcatcaggt ctttttcact gacttccgtc aggaaataca cattgtcctg
    36421 cgacctggaa ttatcaatga ccagataaaa caccttgccg cttttggtgg aaatggtgta
    36481 aaactctttc gtcccttccg ttgctgtctg tgtaatgttt tctgcatctt ccccggatgc
    36541 tgccagttct tcttcaatcc ccgtcacagt acggtcatcc acggttcccc ttgcctccgt
    36601 cggttccgat gcctgtgcgt cctgcggaag cggggatgtg gccgtttctt ccgttgtggc
    36661 agcactgcca gtggtactca tatcgctgtt cgctgtactt tgctgttgtg cctgacgtac
    36721 cgcccattca taatacgggt tctggagagt gtacttatcg gaagtattcc cggcaccatc
    36781 cgtcactgtg atctcgatct gctttgtggt aaaatctttc tgtgtaagct ggaccttcag
    36841 ttttccatcc gaaagttccg tataggtagt accgttgaca gttaccgcag agatcccgga
    36901 taccgcatca tttccctgga tggtcagcac accatccgta agggaggcag aaagcgttgg
    36961 tttttccgta tcataacagc ggatggaacg gttctgttca tacaccgtcc cttctgcatc
    37021 cgtcacccgc acatagattg tctggtttcc gttgatggta atgcttctgg actccgtaac
    37081 gtcctgccag ctcccatctt tcccagtctt tgcttcgatt tttgcgactt taaagccttc
    37141 ccccatctgg ctggcatcta cagtaatgga aacagaagta tctccctgtt tccacccgtc
    37201 cggcttttca atggcgatgg cagggtttgt gctctccgcc gcataaatgc tccgggcaga
    37261 aaaaaacggg gttgccatac ataaaaatgt ggtaactgca aaaacgcctc tttttacgtt
    37321 actgccccat ttcctgtgcc tgcccggtgc cctctgttct ttcattttct ctaaattcat
    37381 catcagctct tgtttcctcc ttctggaatc ctgccagtgt cggcagttcc gttttcattc
    37441 tctcccggaa cgcattcagt tccggtatgg tcatatccat gccacggatg atccgcacga
    37501 tttccaagtt ctccgcttct gtctttgccg cttccgcagc cttaaaccgc ttcaggtctg
    37561 cttcataccg tgccctggat gcctccattt tttcctttgc cttttcataa tcggcaactg
    37621 ctttttcaag gctcttcata ctgctccttt ccgggcggca tgaccaccgc ccttttttac
    37681 catcttccaa atccataaaa atggctctgc cagtaggatg aataaatgga tgtgtactgt
    37741 accggatgcc cgcagtggat catctgcccg ccgcctacat agataccgat atgcgttacc
    37801 ggcacacctg cattataggt tccggtaaag aagatcaaat ctcccggctg gacatcggac
    37861 tctgataccg gtgtacagat atcataaagc ccctgggcag tcagccttcc ggtattcctt
    37921 acccctgaat tggtcaggca gtagcttaca aaaccggaac agtcaaaccc gcttggggaa
    37981 tatccgcccc atacatacgg ggttcccaga tatctggctg cttcctgcag tagcctctgt
    38041 gctgcttcac tggtgtactc atttccacca aaaatggttc cttcccctgt ttccagatag
    38101 aagatcgggt tcatgcgttc cccgtttttg agaagttcca tgtggagatg gcttcctgtg
    38161 gaattgccgg tatttcctgc aagccctatc acatccccct tggtaatggc agcccctgca
    38221 aaaacacttc tgcttttcag atgtgcatac cgcagttcat agcctttgct gtctttgatc
    38281 accacataat tgccatagct gtcattatag gcagaagttg ttaccgtacc ggtcagccct
    38341 gccagtacct ccgtaccttc cggcactccg atatccactc cattgtggag ctggtttgca
    38401 ccggagattg gatggatccg gtatccgtaa tagctgctta cgttgtaata ccagttgaaa
    38461 tcaaatggtg tcccgaacat ctgcaggttg ccctttgttt cgttataggc ggcaaacagt
    38521 tccctctgga aaatccccag acggctctgg cagatgcctg tcaggctgcc ggaatttaac
    38581 gtcacattca aaacatccac atccctggta cgtgtcactt ccacctcccg gcttccgtta
    38641 tcatccgcaa ggaaacactc ccaggtctga tgcccatgtg cggatgccgc cgaatggctg
    38701 tcataataca catcaaactg gacaccgtaa cgggcaaatg ccccggtatc ttctaccgtg
    38761 tattccacac cattcatgac cacctttgtc cccattggaa caaacgggtt ggacgcatct
    38821 accgcaaggg tatggttcgc tgtcgggtac accccggatg ccgtcggtcc tcctgaccat
    38881 atgccacagc agatcgggca gttgcagtaa ccgctcgtca caacatttcc aagggattcc
    38941 cctacccgga ccgtcgttgt ctctgtcaca gtctcattca caacttctgt ctccagctgg
    39001 tactggagtg caaacagcct gtccagttcc ggcttgacct gctcaaaggt aaattcttca
    39061 tacttggcag acaggtagct gatcaaaaca aacgggtcat gctcaatcgg tccgatattg
    39121 taccggtatt cgtcatgtcc cggctcttcc gattccatct ggttgatcct ctcctggagg
    39181 tttgtttcca gctgtgtgta gtaaagatct gcctgccgga ttgcctcatc cgaagagata
    39241 taactggttc cggtgtaatt gatcaggctc tgcataaatg ccgaggaaca ggacgttaca
    39301 ctggtcatga tgaggaacat catcccgatc agggcagcga tgctgatata taccttccgg
    39361 tgttccttga aaaagttggt aactttgccg ccgatcttct tgatatagtc aatcgtgccg
    39421 accgctgcag tccccattgc ctgctcactc tgttttgctt tggaatattc ctttttgatc
    39481 cgttgtttct ggatcagctt cttcaaataa gaccgttcct ggtttatgga agattctgcc
    39541 gcagcctgcg ctgttttctt tgcctgataa gcacttgacc ggctttttct ccggttccgc
    39601 cttctggcac ttctctgttc cagatggtaa agcccctctg aaccttctgc taaactgttt
    39661 gcgccttcca ccgccgcatt gccatcatca ttttttctga cctggcgatg gacagatact
    39721 gccgcagcgg tgcctgcctt tttgacaagg gaagtatctt tcgggctttc cccttcaaat
    39781 ttcagccggc ttttcttttt cgcccctgca ctttctgcat tttcctgata gaccttttct
    39841 ttcatggaat gcttctttgg tgcgttcttc ctttctgcct ccgtgtgagc catcttctgg
    39901 ttccgtttct tctgggcatc atggcggaaa tttaccccgt ccgcatccat ccggttcagt
    39961 ttagctgaag aattaccatc cctgactgcc tccgccgtct cctcataggc aaacttcagc
    40021 ctctgcttct gccccggctt tttacttcct ccgttctgtt tcttcctcgc atctcccctt
    40081 gactgggcaa ggtctgtatg cttctcctga agtttcccac tgccgttttt cttctcttcc
    40141 agtgacagtt tggaactgcc ctctgcctgt tcccggatca ttttccggga ttttgctttg
    40201 tctactgtct gtgcctttgc cggtgcatcc ctggagttct gcacagaatg cctgaccgga
    40261 tccgtactgt cctctctcgt ccctctccgg ttggaaagat ccatcccttt tccggtatcc
    40321 ttttttgaca tctgcacatc ccgggtacgg ctgctgacac gaacagtgga tttatctgcc
    40381 aggttttctt ccactaaacc gtcctttgtc atcttctgga cagttttctc cctggctttc
    40441 attctctgtt ctgccatctg ttacctcctt catttttttc ctgcatgcac gatacaggta
    40501 agaaccagac cacataccat acctgctgta aatgtcagaa aatatgctaa tacatgcatc
    40561 gtttttcctc ctatgcctga tctcccgtct cttccggacg ggtggttaat agctgataca
    40621 gtttgttctt cgggaacctg tccacaaacg ggatgatgac atttccatag aacaaaagcc
    40681 cctcaccttc attgctgttc gtcacatagg acagctgggt cggtgaaatg ttcagctgct
    40741 ttgccaggat ctgccggtca ccggatgcct ggttgagcat gtaaatgaaa tccgagttct
    40801 atagtgatag gtaagcctct gatatcatct cgggcttttc ccccactcca caccgtgcat
    40861 gcgactttca ccgcacacgg cgttccatcg gttagtattt ttcattgtct aaacaatcaa
    40921 cctttgaata gaataaaaac tgtagtagtt gaaataagat taaataggtt gcatggaagc
    40981 caactcacga aggtggttaa cctttataag ctgtttgtta tctagctgta gtaaatccat
    41041 atatttgtaa atagtttccg cttttgaagc atgaatgagt ttatggacgg aattctttat
    41101 gagaataaga ttctcatagg catccgtacc gcctaaatgt cgaggtaact tatgatggca
    41161 atgaatttcc ccaacagagg agaattcaac accggttata gcacattttc cccattgggc
    41221 tgaaaagaga gatattcgat tgtctgcgta ttccgcacta ttggaataga ctggttgacg
    41281 catgagagcc aacatcatag ggatgttgat tctcagacag ttgtgaatac cttcacgtcc
    41341 ttcgggagtg taataattcc agctcttctt acggaaaagc ggatttttgt gctgtgtgta
    41401 tcctattgga tacacgggct cattcgtacc agcgacatat cgcatcattt tggatttacc
    41461 aaaacgggct ttttcaaact ccgtaagctc tcgccctgtt ttcacaaggc ggttgcctgt
    41521 gcgagtgcta agcctgtttg tcagcaaggt catgactgtg cggttaaggg aagcacaatc
    41581 atgattaaca tgtgtggcaa tacagtagta attctgcatg ccagtgacca tactgttata
    41641 gagtctgatt tcaccctgtt cgccatatat tttgcgaggg tgagcaattc tctttgcctg
    41701 ttcttttagc ttctcccttt tgtgctccag atttttatct gcgatatgag atataaccac
    41761 gagtttgttg cccttcctgt gcactttcat tttgaatccg agaaaatcag aataatgatt
    41821 tcttacattt acaatcctcg ttttcttttc agaaatttcc agtttgagcc tttctttcag
    41881 ccacagagtg actgcacatt tggtgcgttc agcagagtcc ttagtcctgc aaaagattcg
    41941 aaaatcatct gcatagcgga caatgaacat ttccttcagg ttagatttct tagcctgtcg
    42001 atagccattg tcgggtctgg tattccgttt gcaaatcgga caccattgcc attgactttc
    42061 cacccagtgg tctaattcgt taagcacgat attagccagg agtggcgata tgatacctcc
    42121 ctgtggggtt cctttgtcgg gcgtgataaa agtcccgtcc tccagtttga taggtgcttt
    42181 gagaattcgt cttatgacaa aaatcaactt cttgtcatga atacccatag cccatatctg
    42241 tcgtatcagc ttggcgtgat tcacattatc aaagaatcct tttatatcga attcaatgac
    42301 atagtgaaga ttggcatgtt gaagcagctg ataacttctt gctatggcat tctctaccga
    42361 atggttcggt ctgaatccat agctgttctt gctgaactta gcttcacaaa cgggttccat
    42421 tacctgtttg atacattgtt gaacaagcct gtcccaaata catgggatcc ctaggggtct
    42481 tgtcttactt gggtcgtatg gttttggtat ctccttacgc cttacaggtt ttgggcgata
    42541 cccatgttca cttccattaa taataaatct aactttttca acaacttcat cgggggagca
    42601 tcttccgatg tcctcgattg tgagattgtc tgtgccattt gttttacttc ctgtattttt
    42661 cttgatattt ctgtacgcta gaagaatgtt ttccctttga aggatgacag acattaaatc
    42721 tgtgaaaact tctccgttca aacttgcctg gtatagatta tcaatcgtat tctgcattcc
    42781 gtaatactcg ttgtgacgca gattatcttc acatagcagt tgctttttct ttttcatggt
    42841 cataaggcat cactctcctt tcttgggaaa gtgtcccttt ttgtcatact cgtaatcctt
    42901 ataagattga atgacaataa ttgtttctaa ccgactaaag cccattcctc gagcccgcct
    42961 ttttcgtagg gctgtcatag gttcgagctt cgcttttcag cacagattaa gcggcttata
    43021 tgattcgtcc gcagattgct tatgagcaac tctgtacctt tccacgttcc gataattcta
    43081 tctgtgcata tatccttagg tgtccgctat agtcctgtca gcttgattgt gcctataaca
    43141 caatacggag tttcatattt tcgattctta ctccaccgca ctgacccaca attaagtgtc
    43201 catacatttc tatatggtaa acatctagac ccgtacattc gcggttttcg tcagtccgtc
    43261 gtggacattc tcaccataga tattttatag actcccgacg tgtcatctgc atacggtacc
    43321 tctaccgcac tttcgacagc tgtatttcta cactgtttcg gcagacttcc gccgacttta
    43381 tcgagctcca gaccccaacc attacagtca gagccggtcg aagtatcaga gaaggcattt
    43441 cagggcgtta ccccatcatt ctacctttcg aattatcagt tgttgcttac ctcgtatgga
    43501 agtaagcccg acgattttag catcgcatgg ccataagtct atgaagtttt accctcatag
    43561 agcgatgttt gtgcgtcaac gtgtcgcacc aaaaatgttc tcaatctcac ggcttgccag
    43621 aagatccttg atattctggg tgataccggt cgggatacct ccccatttac ggaacctctt
    43681 ccagatctcc acactgtagg ctgccgtctg ctcttccttt aaaagcagat ggaattcatc
    43741 aacatagtac cgggtcgatt tatgggcgga acggttgacc gttaccctgt tccaaacctg
    43801 gtcctggacg atgagcatcc cgatcttttt cagctgtttt cccaactcct taatgtcaaa
    43861 gcagatgatc cggctattga tatccacgtt tgtccggtgg ttgaacacat tcaatgaacc
    43921 ggtaacgtaa atttccagtg cggttgccag ccgctgtgcc tccggttcat cctgcccccg
    43981 gagcaggtca tacagatcct gaaggatcgg catcttctcc ggcaccggat cggaaagata
    44041 ttcctgatac acaagacgca cacaccggtc aatgatggtc ttttccaccg gttccagacc
    44101 gttctttcct cccacgatca gctcacaaag agacaaaata aaatccgatt tcagagataa
    44161 aggattatcc tcctcggaat agttaaggtt taagtccatc gggttgatat actgggtcga
    44221 taccggtgag atacggacta cctgcccatg cagtgcctgc accagcgggt aatactctgc
    44281 ttccgggtcg cagatgataa tgtcatcttc cgtaatgagg aagcagttgg taatctccct
    44341 ttttgctgag aaggatttac cggaacccgg tgtacctaag atcagcccgt ttgggttttt
    44401 aagccgcttc cggtccacca tgatcatgtt gttggacaac gcattcagac cataataaag
    44461 ggcttcccct tcctggaaca gttcctgtgt cgtaaatggc acaaagatcg ctgttgccga
    44521 ggtggtaagc ccacgctgga tctcgattct gtttactccc agtgggatac aggacatcag
    44581 ccccgcttcc tgctggtaat ccaaaggacg cagggaacag ttatacttct gtgcgatgcc
    44641 ctgcacctgg aaaatgttgt tgtccagttt ctgccttttc tttgccgtat tcatcacaag
    44701 gacagtgaca aggaacatcc tctcattcct ggactgcagg tcttccagaa ggttcttcgc
    44761 ttcttcccca taggtcacaa ggtcagatgg cagcacatcc atgtcatagc cggaacgcac
    44821 cgcccgcttc tgctcttcaa tcttcatctt gtccaggtca gagattttac tcttgatcat
    44881 cttgatggca gaggtctggt caatagactg gatatggata ttcacattga tgctctcatc
    44941 cacatccaga aaatctgcca gcatacggtc agtcagttcc ggtgcgagga tctgcaggta
    45001 gctgacgctt cccagtgttt ttcccatcat aaaagaggaa ttctttgaga aattaaagga
    45061 tgtcggtgcg ataaaatcct ttgtcttaag tcccgtctgt ggaagcatct tgtaattgaa
    45121 ccggaacggc tcgatccggt cctgattgaa cacatggtac atgatctcaa gacgctccac
    45181 cccgttcaat ggatgagcct gtgccccaag cactttaaag ttgttgagga tatccgcctc
    45241 aatccgctca agcctcggtc ttgccacctt taaactctcc gcttcaatcc cgaacgtaat
    45301 atactttgat ttcaccagac cgttattccc tttggaaagc tggttcttta acatcgtccg
    45361 gtattcttcc cggatctcgt tgaaatcatc attctggtcc gggatatcaa tgctcttttc
    45421 aaactctgcc acatccacct gctggttgat aaaagacagc tgcacactga tggacgagtc
    45481 aaagtaattc aggaaatcac agtagttttc aaagatcgtg gtcttatcct cattcagggc
    45541 aagctggtaa ttgatatcgt aaaactgtac ggttttggaa aaaaagtttt tcgatacctg
    45601 gcagatgcca tccgcaaaca tccgctgata agggatgctc tgctgggcag tatggggaat
    45661 gttcttctgc cgtttccttt ctttctcctg ttttttccta agcttttcct tttccctttc
    45721 ctttttgtcg tttctttttc ttctttcctg acggtttttt cttgccgccg cttccaggca
    45781 ctgctgctgt gcctgtttct tcttttttgc catccggcac gccctccttc tttacgaggg
    45841 aatccaccgc ctgatagaag ttctccgtct tgtacggacg tttcgccgga cagatgaatt
    45901 tctggcggat gatatttccc atcacttttt caaaagggag accgtctttt tcatacattg
    45961 ccataaagaa aaatggcagc atgacagtta ccataaggat cgctgacaca ctggaaccaa
    46021 ggggtttctt tgccagcagg tataacggga ctcccactac tgcggcaagc gaaaaaaaga
    46081 tcagctgccg ctttgtcagg ttcaatgcta cttttgtctt gaccttggta aggtcttttg
    46141 gtactggtac atacgccata ggtagtactc ctttcttttc ctgcccatca gtgggcattg
    46201 aatattgatt tactgaggct tccggtctta aacagtgaaa atgccagtac gaccgtatat
    46261 gccgccactg aaaacattgc cccatgcagg ttcgtggata tggtcatcgc attgaccaat
    46321 acggaataaa taccgacaca gaccagcatg aagaatccct gaaatgccag ggcgaacaag
    46381 cctttcagat agttgttccc gatattgccc cattccttat tggtcatggt ggcaaacggg
    46441 atcggtgcca cggaagtata aaggtagatc tcaatcatcc tgccatacat gatcaccgtg
    46501 ataatcacgg agaggatgct catggtaagg ctgatgagaa gtgtttccat tgccagcaaa
    46561 aacagttccc cgatctccat ttcttccaaa gattccgtca gggtagcaat ggcggcagaa
    46621 gcatccaccg ccgtacttcc ggagatcaca ccggctgcac cgtttacgat gtgctgcccc
    46681 acatcgaata ccgccattgt gatattaaat gtgttcgtca caaggtaaat cgccacatat
    46741 gccttaaaga tccagagaaa aatgttgtaa gtttcgaact catggaagtt attcttctgt
    46801 gtgaccatcg tgatcagctc ataacaaagc acgaacgtaa tgatcagacc ggcgatgggc
    46861 acgatcaccg tctgagacag gttttgaatg aggttaaaaa cccctgtgtt ccatccctgc
    46921 ggtgtctgcc ctacctgact ggcaatcgtt cccaccttat cattgacctc cacgaacatc
    46981 ccttccagac cattctggat catcccgatg aggatctcct tgatggcttc cgtgattcgt
    47041 tcgataatgg tgttcatcca ttaccccatt aaccgaacag cgttgccagc tggggaatca
    47101 gggtagttcc cagcagcatg attccagctc ctgccatgag ctgtttgatt ccctggctct
    47161 ttgcgccggg gttgtcattc ccataacctt ccagaaggtt gatgacaccc catacgccaa
    47221 ggcccgcccc gattgctacg accagggtct tcagagtagt aattgcactg gtaaaaaatg
    47281 ccatataaat caccaaaact aactttgccg ggtgtaaccg ggaatgaaaa acgccggtaa
    47341 caataccggc gcaccctgtt agttattcct ttcctcatta ttttcctgct cattcccgtc
    47401 ttctgaaaga tccatttcca tcacttccac ctcatcatca ggtttcggtg agtacttcgg
    47461 atccagttcc ttttccacct taaaccggtt cttctcactg taatccgcaa ggagccggta
    47521 attggggtgt ttggttatat cgtatttgtc cgaatagaac ggacggacac cacgtatctg
    47581 caggatgcat ttcccgccgt ccatgactgc gatctcatcc tccgtcatca gctgtttccc
    47641 ggttttctgg taattcagcc cgaatgactt ctggttgctg cgtgtttccg aggtgttata
    47701 aaggtcaatc gtctccttcc ccagaagctc actcatctct ttcagggtgg tcttttcctt
    47761 gcccccaagg aacaacatcg tgtcacaatt ccccagaatt gtatccgcac tatccttgta
    47821 cattgccttc agctggctct gcgactgcaa aataatagaa gcagagattt ccctgcttcg
    47881 gatagtggca atcagcttat caaactgtgg aatctgcccg atgttggcaa actcatcgca
    47941 gataacccgt acatggaccg gcagcctgcc gccatattga tcatctgcct tatcacagag
    48001 caggttgaaa agctgggact gcagcatggc gatcacaaag ttaaaggtgg tatctgtatc
    48061 tgacataatc agaaacagcg ccgtcttccg gtctcccacc ttatccagtt ccatctcatc
    48121 atagctcatg atctcccgaa gctcggcaat atcaaacgga gccagtctgg caccacagct
    48181 gatcaggatt gattttgctg tcttaccagc cgccagcttg tatttcttat actggcgtac
    48241 cgcaaagtgt tccggattcc ttttttccag atcctcaaac agcatatcca ctggattttt
    48301 gtaattctcg tcatcctccc tggtctcgct ttcattcaga aggtcgatca gggtgttcat
    48361 gttcttctcg tcctcgtccc cttcatacca gatcagggca atcagtgccg tgtacagcag
    48421 tttttctgct ttgacccaga aatcctcggt tgccttttcc ccttcccctt tggtgttggc
    48481 gatgataacc gtcaccagtt tcaggatatc cttttcggat tttaaatagg caaacggatt
    48541 gtaatgaagc gatttagaga agttaatggt atttaggacc ttgatcacat aaggctcatg
    48601 caccaccttc ccggatttat ctttcacaac atttccatgc ttgtctctct ttggcggtcc
    48661 tttggctaac atcttcccgc attcttcgat aagtgttccc ttcggatccg tgatgaccat
    48721 ggaacagttc atcatcataa tagagacctt tacgaaaaac cttgtttttc cactgccgga
    48781 accgccgatg acgcagatgt ttttatttct ggcaaacttt gggttcttcg gacggctctc
    48841 catggtaatg gattccgttg ccgtcagcgg aatgttcatc cagaaatcat ctgccataaa
    48901 tggtttgatg tcttccgctg ttccccacct ggcagagcca tactccacgc ctttgcggag
    48961 cttttttgca tctgcctgtt tctgccagac cagtatcttc acaactgccg caatcccggc
    49021 acccaccaga acatccatgt agtaaagact tggcaggaac ccggtcaaaa tccggtcagc
    49081 atgttccatg gcatataata gtttgtttcc catatctgcc ccgggacttg cccggtacag
    49141 acaggatgcc ctgtctgcaa gcaaaaagat gaacaggtac ggaagattgg tgagaataag
    49201 ctttttcata tccaaagcgg acagcgtaac tctggctttt gctttcagct tgttagtcat
    49261 accaccggca gtaagctttc tcaccgggat acctcctgat gcttattcct ggctttgccc
    49321 ttcgtcttcc ctgcaacaat actcctgtat gctgccagac gtttgtgtat ggaagggcgg
    49381 ttcgcctttt ggatctcttt ctgggaaaat tcacggaaag ctgcggtgat cgcatcctgg
    49441 tcacgtccct taaagaacac catataaacc ggaggatctt tggtcttatc ctttttcagg
    49501 gcataattga tcccgtattt tctggcatac cgttcaaaag acttgatgtt cttgggtgtg
    49561 atctcaatat tcgtcatccc ggcattctgc tttgccagct ctttcaccgt gattttcccc
    49621 tgtttcggct gatttttctg tgctttcttc tcagcacttt tctgtttctg atgccgcagg
    49681 tatgcggcaa tcactttttt cagcacatct gccgtcattt ttgtggtacg cacacaaaaa
    49741 gtcaccgttt tctgtgttac ttcttcctgc atgaatttcc ctcctttcag cgtattactt
    49801 gctgtcccaa cctaagacca ttggtatcac ccctttcatc aaaaaaagaa ccgatcaacc
    49861 actgatcaga ctctgcatcc gaccgagctt ttccgttcct tcttcccttc ttttgtctgc
    49921 cccgccacaa tagacaggta cacacatctc caatattctg ctgtaaatcc gcttatgggc
    49981 tacatccagc gcttcatctt tcatatcatt caacccgaga tttgttgtga tgatgagagg
    50041 cttcatttta cagtacctgc tgtcaatcac gttatagatc tgctccaggg caaactctga
    50101 attacgttct atccccagat catcaataat cagaagcggg taatccacca gattctgcac
    50161 aatctggttt ttatctgcct gatagtttgt catttcattc aggatacgtg agaagttcgt
    50221 catcatcacc cgctccccct gttccagaag ggcattggca atacacccgg caaaaaaact
    50281 cttcccagtc cccaccggac ccatcaggag aaggcctaca ttttcttttt tcatcttctc
    50341 ccagtttttt gtatactgcc tggcaatgag catcttatca tttgacccat tatcattttc
    50401 aaatcgccat tcccagaacc tccggtctct aagtcctacc gattttctct ggtaaagctc
    50461 cctctgggct tcttccctgc ggagctgctc ttctttttct tttcttgcct gagcctcgca
    50521 gtcacacagg cagcccacta cacggtccct tcccataaaa ttaatcctca gctgtttccg
    50581 tttcccgcat acaccacacc ggaggcatcc gtcttcccca agaaaatcag ccacattcct
    50641 gctatctgtc atagactctc tccttcctca aagtcatatc ttccagaacc ggttttcagt
    50701 tcttcccttc ctgcccagag aagaatcgtt gcgaaatgat cctgataggt ttttccagtg
    50761 gatttcatat aagctgaaag ctggtcaatc atcctctgga agtcatacgg atacagtttc
    50821 cgcaactccc ggttttcttc cacggaaagc cggacatttc caaaccgtcc gtacagacat
    50881 gtgctttcct tttccgaaga gcggctctta ctcctgtcag tatcattctt atcagtctta
    50941 tttatatcag tattatttgt ggcaaaattt ttgcgttccg gacttccaat tttttgcgtt
    51001 ccggactgca atttttttgc actccggact tccagattct tgcgctccgg acagcaaatt
    51061 tcttgcgttc cagaaggata ataaactgcc ggttttgccc ggatgcgttt tacgaagttc
    51121 ttcacatata tcaccgatgg acggttgcag ccctgtcggt accgttcgat cagaccgatg
    51181 ccatgtacac tgtcaagctc cctgagaagc tttgtgaccg ttgtgtgtga catgtgcagc
    51241 acttcctgaa gttcagctac cgtgtagatg atatacacat aaccgtcagc atccacccag
    51301 ccatttttct ttgaaaggtt gatcctgtcc agcaggatgc catacagaag ctttgcatcc
    51361 gtggacagcc cttcaaattc cttttctgta aacagtgcct tgggaatacg gaaaaatgaa
    51421 aactgctcgg attcttctac ccggaagtat tcataatcca ttttttcatc ctcattattc
    51481 catctctttg ttcttgaaca tattcaggta catgttgaac acactcacca gttccttcag
    51541 atagattcgt ctggcacctt tgttgcaggc gtgcatatct tcgatccatt ccggggaatt
    51601 tccgcagatc acagccgttg tctctacgac agccataaat ctcttcatgg attccatctt
    51661 gtaaacatgg ttgaaatact ggcggattgc ctcaattcta tccggatcat tttccagtaa
    51721 ttcaatgaca ccgaaagcca ggtccatacc aaattcactg gcatcatctt cgattgcctc
    51781 atcatccagg ttaccgttct catcacagta gcatctgaat tccatcggac ttaaatcttc
    51841 cggattaaac tcgtcctctc ccagatcaat tggcggtaca ccatcctcca gaggccctcc
    51901 ctccggacag ccttccctta taatctcgat gtagcctttt ttcataaggt catccacaat
    51961 ttccctggca gctgtcacca tcttgtccat gatttcttct gcctcctccg ggcctaccat
    52021 tgtcattaaa tcattgattg tcatcatagt cttttcctcc tcattcatct ttgaaatatc
    52081 atttatatag aaacggttcg gtctgccatt gtctttaaca acccgaacca tgtttcccat
    52141 actttccagt tccgaaacag cataatccat ccggtacctg gtgctattca gatccctgat
    52201 catttcactt ttgggataga tcacatacgg tctccctttc tggtcaatcc atttgttttg
    52261 tgctgcatat ctcagccggt caagcataag gctgtataat acctttgccg tagtggataa
    52321 agagcaatat ctcgcatcct taaacaatgc ctttggcacc agcaggcact ctaccggcat
    52381 ataatcctga ttactcatca tgcttccctc cattcagatc gaccattgcc tctgttgaga
    52441 aaacagtcaa atccagcatt cccacaaaaa tctgataata cagggaacaa agctctgcat
    52501 catcccttac cagatacaaa ccttccagtt cttctgacag atgcctcatg gcatacatgg
    52561 tctggcagag ttcatggact ttttcatagt cctgtctttc cacgttcttc tccagacggt
    52621 caacaaaacg gctccaatct gtaaagttgc tgtccattac aatcaggcac tggaacagct
    52681 cggttgcttc acaggcagcc gccaatacta catttttgat attgatggaa ccattttcat
    52741 ttctcatgtg gttgatcatg tactctttat ttaacattac cattggctta tcctcctatc
    52801 gaaatggcat ttcttcttcc atagattccg ggatgttcag aaaaccatcc ccttccatag
    52861 gctccggcat tttctcctgc acttttgcac cggcaaactc gatacggtct gcaaaaagct
    52921 ctgtcgtata tacctttttg ccggtctctt tattatcgta actgccggtt acgatttcac
    52981 cctctaccat tacctttgtc ccctgcacca gataatcacg gacaaactcc gctttttttg
    53041 caaaggcttt caccggaatg aaactgacat cgtctgagta attccttctg actgccagta
    53101 caaacttggc aatcttatga agacctttct cattctgtgt ctcgttatag cccggatcac
    53161 gaaccagtct tccggaaata attgctgtat tcattacctc gcatcctcct attctttcaa
    53221 tgttttatag cacagcccga tacatggacc acacttggca taacaacagt cgtaacattc
    53281 atccttttcc agttcctcct gtgccatttc agcctcaaac atactcataa gcagttcata
    53341 cgcagttttt aattccagat atttctcttc tgctttttcc atcttccttt taaattccgg
    53401 aagcatctgg cgaagaactg gatggaaatg ttcttcttca tcatcccagg cacaggatgc
    53461 catcatgcat cttggaaatt tttcataact tcctgcataa taagggcaat aagaacagcc
    53521 cctttcccgg aacatagccg gtgcaataac cggaagctgc cctctgattt ctttcgtaat
    53581 ctgtttgttc ttgattcgct ctctcatgtt cgttctcctc cgtctttttc tttatgcaaa
    53641 aggggattcc ccctgaattg cctgctttat cgcacatttc gcagctttgc tgctcaatga
    53701 ccgttagctg tcaaatacaa atccaaaaca tttttggctt tgtactttcc agctttatcg
    53761 cacaaaaaaa ggcaggctta cgaatttgtt ttttcgcaag cctgcctcaa atctgctact
    53821 cattatcttt ttactatata ccggatggtc acatagattg ccctcacaat ataatatggg
    53881 atcataaggc ttcccaataa accacccaca ataacactca atgcgatcat tccaacagta
    53941 cccccaacat catagcctct ggggattaaa atgatacaca ttttatgtat tccaaacgga
    54001 agccctgcaa ggaataggaa cataaataaa tctgtattcc cggtcactcc cataatcgtt
    54061 tttaccatcc agagccagaa tgccatagct gccagtggta acaatgcctt cttaatcaca
    54121 tccatgattg tcattttgaa cacgctcctt attgtctgcc cattcctcta acaatttaaa
    54181 aatcacatct tctatctgct cttttgtata actctccgga aaaaacatcc ggagcttctt
    54241 ttccggcagc ttcacctgta atttctctgt tttaccctgg caacagatac aatcaatttc
    54301 cgaatatgtc agtaaatgtt ccttagaaca cttcttcatt tcctgtgcct gcttcatgga
    54361 cggaaccatt tcatggttac ccatatactg aagcaatata tcctgctcct cttttttcaa
    54421 atatgataat tcgacagcag tattaaacgg gagctgttta tggtcagcca tatccagaag
    54481 aaccggaagt aattccgtca gatggatata cctgagaatc tgccgtgtgc tatcctctga
    54541 attttggctg atatcctctg ccgccaactt cttgccaact tggcaagaag ttaaatcact
    54601 tcgtttgccc tggcgtttca atgcatcata tttcatttta taggcaaatg ccttttcact
    54661 gatcaacagt tcttcacgct gaatgtttga atcaaccata atcacagtcg attcatcatc
    54721 tgtcaagtct ttaataatga ctggcatggt tttcaaacca gcaatctcac acgccctctt
    54781 acggcggtgc cctgctataa tttcataacc gccggtgtcc tttattctca caataccagg
    54841 caccaaaact ccatgcgtcc tcacgctttc agacaactca atcatcttgt catcatccag
    54901 aaccttaaac ggatgattag agaaggaatg cagattatcc agagcaatct gttggatgcc
    54961 tgcctgttcc tcacttgttg ttccgaatag ggcatctaat gactgtaatg gaattggcgt
    55021 tgatttcttt ttacctgcca tgttcaagaa cctcctccgt aaaattcata tatgctttcg
    55081 caactttacc ttttggttcg tatttaaaaa tactctgtcc ctctctgacc gcttctttca
    55141 tcctgacaga aaatggaata taattgtcaa acacatgaat ttgatttcca tatgcattat
    55201 gaagcagctc catattgttt cttgcatcat ttgtatgggc atccaccata ctgaaaagga
    55261 taccggcaat ctgtagtttc gggttaatct gtcttcttac tttgccgatt gtcttcaaga
    55321 gctgctgcag tcctttgatt ggaagataag atgcttctac cggaatcaat acttcatccg
    55381 atgctgccag ggcattgatg gtgatcatac ccagagatgg catacaatct atcaaaactg
    55441 tatcgtacct gtcttttacc ctgtttaata tctgtttcag gacaaactca cggctcattg
    55501 cattcacaag ctgtacttct gttcctgcca atccaatatt ggaacagata atatcaatac
    55561 cttcctctgt atgctggata aagcagtctt ccggaatatc ttcatcattc aacaccattt
    55621 ccatcagcgt tgttaatgtt tcattactat tatcgcagtc acggaatcca aatccagcag
    55681 acacatctga ctgaggatca gcatccacga ctaacacctt cttattcata agagccaacc
    55741 ctacaccaag atttgccgca catgcggatt ttccagttcc gcctttctgg tttactactg
    55801 atataatttt tgccatattc tttatcacct ttctttgatc tcaaataaaa aagaggactg
    55861 aaccagacgg ccagaactaa tgtccgtgcg agctaattca gtcctaaaaa taagtatatt
    55921 cagttatcac cgctttcgtg gtatgcaaat ccatatccag tgttctggac ttacaataat
    55981 tcgtattctg gaatgacagc gctgcctcat ttatcccctt ttcagggaat taaaaataag
    56041 gactaaatta gtgcaacccc ctgtatttcc tagggttttc taacttgtcc ttattataac
    56101 tcaatcatgt ggcgtaatct ttggtagctt gtcctcatga gtcttattat acttcttgac
    56161 taacgctctt aacatgcttt gataattggt tgcttacttt ggtaacccat cacgtttaag
    56221 gaataagaag ttttgataaa catcaacaat gattggtttt gctttagcgt tcttacgccg
    56281 ttccacgata cgttcaaatg attgataagc tctttctcag tcattggaat ttctcgctta
    56341 ccctgtgtgg tctttggaac ttctacataa tagccaatct tggtatcact caacaattga
    56401 tggtctacca taatggcttt atttttcata tccaattcta aagtcaaacc gcataattca
    56461 gaaatgagta gtcctatttc taagaggata acaacatcat cataatattt acaataagta
    56521 ttatcgctct ccataaagga taataagtcc atttcctgtt ctgttgttag agcgattttt
    56581 ggttctgttg tatcttccaa aacatcactt aactgaaaat caaatggatt ttttctaata
    56641 tagtcgtctt gaattgccat gaaaaacgac gctttcagtg aacgcttata attgtcaatg
    56701 gatttataag cacacccatc ttcactcatt cggatagccc agcttttagc gtctgataat
    56761 ttaaccatat caatgctttt cgcacctagt ggcttattgt tcagaatatt cataagataa
    56821 tggcgtcctt taaatgctat tgcgttcgaa ttaaactata tacatggcaa tcaatcatgt
    56881 ttctattctt tattatggaa ttgtgacagt attcttcaat cttaaaacca catttttcca
    56941 atactttact tgaccttcta ttgtaggaat atacattagc atgaattttg ttaaggttgt
    57001 atttttcaaa ggcaattttg catatttctt ttactgcatt tgttgttatc cctttacccc
    57061 aatagttcct agcaagccag taacctaata cagcattttt attaatagag gtatcttctt
    57121 caaatgttag gctgatactt ccaatagccc tttcttgata aaaaatagca tagctaagtt
    57181 gtttaacatc tggagttgcc aaacaaaaac taataaaatc tctagcgttt tgctccgtat
    57241 aagggttggg gaagttgtca cgaagattct ttgcaatttc tttatcattc gcaaactcaa
    57301 ctaaatcggt aatataagca taattccact ctataagttc catttttctt ctccttttat
    57361 gaaacagcta caagaaatct ttctaagcca ataccactta tcaaacagcg ttctttttta
    57421 tttccaagca tttgataagt ccagtcaaca aatccaccat caaccatttc aacggtatca
    57481 tttccttgtt tgaccgataa tttgaaattg atacctttat aataattatt atcaacatca
    57541 tcattatgaa ttgataactc tatattagga aaaataagtt tgatagtttc aaccattctg
    57601 tcgaaaaatc cgtcattatc tttgtatccg tttcttttgc gtagaataat agagaaacga
    57661 acattttcta tttcacttaa tatatcttta taatagttta agtgcttttc taacaacatt
    57721 ttttcacaag tgtaagaccc tgtatctata ccagatgaaa ccatacaata taagccaaaa
    57781 tgtgaatata aacctttacc tacaaaattt tgtgctctta ttgccctagc agtagtagcc
    57841 atgtggatag gtatggtatt attttcttct tttcttttta atttatcagc aataattatt
    57901 gccaacatat ttgaggggtc tgcaagtgtt tctgtccctc gtagagcact tactacgtta
    57961 tattgatcta cggagccaaa aacgctacaa ctacctaatg gagcagatgg agaaagcata
    58021 atcgtcttga tatccatatt gaatgctttt ctcaataatt ttgattccaa agtatgaatt
    58081 tcttctggat ctatactgct agggatagta aatctattta gttggtatga ctttagaata
    58141 tcagttgcag ttaaagtatt tgcttgtcta tcaaacactt ctaatagaag tgagttcaaa
    58201 tctgattttg atagagctga taacttatca actatattct tatccccaat tttatttgaa
    58261 attctactta aaatatcact catagttatc ctccttactg ttactttcaa aataattata
    58321 gaatggttac aacaactaat ctaggtcgtt tgaccaaaaa tgaaaaaaca ctgaatattt
    58381 accattcaat gtttttttac tttgggttta tttgattaaa tcttgaaaat actgtaatgc
    58441 aaccctttca gcttcaacct ttcggacaat aggactttgt gataattcct ctcttaactc
    58501 aagatacagg ttgatagtag cctgcaatgc attaacacag cttctatatt catgggtagc
    58561 aaccgtcttt tctaatgctt caatatattg gggtgcatcc aattcgattt ttctaactcc
    58621 acgaggtaat ttacctaaga gaagctgtat caatggggca agtactgatt gtcttaaaaa
    58681 agataaaaaa tcaattgttt caaatagttc tctacgtcca atcttagtgc aagcgtaatg
    58741 aacccaaatc caaaatctat cttcaatcca ctgtaagtct ggagttggga agtatgcttc
    58801 ttttttagaa taaatttctg ttatgcagtt gttttcttca tagagaatag ctgaatcttc
    58861 aaccctatct agtaaaccat ctaaggttgt aaacttaaaa tcaacatgaa gaacagggga
    58921 atcatagagg gaaattatca atcgaggttc tccaacgtgt tcgccagtaa aagcagaaac
    58981 taatgttcca aactgttcca caataagtaa tctctcttcg ataacttctt cataggattt
    59041 atcatctgct acaatcagaa aatccaaatc agaatattca tctaacgatt ttgtgatata
    59101 agaaccgcta attgcaagtc ctattatcct actatctctt ttggaaaatt ctaatacgtt
    59161 ttgtatcatt tcctgttgtg ttttagtcat aatataacac ctctcacttt cttttattag
    59221 ctatcaatcc aacataatta tgcataggag tattatataa tgaagaaata aaaaaaaata
    59281 ggtcacttga cccgaaataa aaaagtattg aataattatt atccaatgct tttttgaaat
    59341 tatacttatg ttgtaggaag attctttaat acctctcgct gattaattac actaaatctt
    59401 ttgttttcat aagcaattag atgttcttgt acacattcat ttatagcacg attaatgctt
    59461 ctaattggag cgtttacttc gctagcaagc tgttttttgg taagcagatt taattcactt
    59521 ctataatagt gtaaggatat acacttcaga agtcgttctt taacacttaa agatgataat
    59581 tcttcaatta attcagcatt tacaactaat ttactagata tttctcgaat cagaaatttt
    59641 gtagcttcaa aatctccctt tagccagttt aaaaaatcat ctctatgaag tttatataca
    59701 ttacaatctg tgaaagcgac aatttcaacg ggttttttcc catcattaaa ttgttccatt
    59761 tctccaaaaa aactaccact tctataaaga tgaatagttg agatgtttcc tttcgcattt
    59821 aagatgaatg cttctgcaat accgtcaatc ataagaatta catattcatt ttcttgctca
    59881 gcaaaaagaa tagtctcttt ctttttatac gtttttttaa caagcttctt tttaatatct
    59941 tcattcataa aatcaattaa atgcatattc atccctcctt accaaatatt tgattaaatt
    60001 atatcatctt tcaattagtt aggtaagata gtaaaaatat atttacatag aaactattcc
    60061 attattattt tccagttgtc atttttctgc aaagtaagct caaactggga aagctgtgta
    60121 actttggttt ccttatcata gaaaaggaac accttttttc gtgttccatg ttctattaaa
    60181 tatttagttt tatttgatac aatactgagg tgtttatacc gtatttttgc atttctagga
    60241 cttatcaacg tatcaaggct cattcggtag tagtaaatta gtagtaaaat ggctttgtta
    60301 gtcctgtgta tatgcggata ggtactgtgt tctaggggat aatcagattt ttagtatgtt
    60361 ttttaaatta aaataaagcg taaatttttg attatcttct tataaactta ccatgttgcc
    60421 agtatgaccc tattttatgg gttttactgg ctttttattg cctccaatta tacataaata
    60481 cagttatttt tttattacct atgcttaaat ttctataaaa gaaaaaacag ccaacttttt
    60541 aatcaaaatt aactgtgttt tatattcaat atttaatttt catttttgta ctccgttttg
    60601 tgctccgttt gttagatagc agagacctaa tgagtgctca cagtttagcc caaaatctga
    60661 agtgagccaa ctatttgctg tgattaaata gtttaccttg aaacttaaat ttatcttcta
    60721 aaattatctt ttaaactgac gatagcaaaa atatatgtat tctttcattg atatttctct
    60781 actatgtaaa attcctatga taacaaatat tatttctgca acagtaagat agcagtcttt
    60841 taagtcgaaa ataaaaaagc ttggtatctg caaaaaatct aaacttcctc cccaaaataa
    60901 tttatctatc aagctacata ttgtaccagc aagtccacaa gacataatta cttttactga
    60961 atagctcgtt tgttcatttt ttgatttgta aaaagcatat ccagatataa taactaggat
    61021 aactaaaatg ttaaacaata ccaataccca taaattagat agaataccaa taaaatttcc
    61081 tccataagag agatttgtat tttgaacagg attgaatctt aaaaattttc cagttatatc
    61141 aatttcaaag cccattaaga ataatcctat aagaactttg ctaatttggt ctaagaatat
    61201 taaggatata actggaaaaa caaaagactt tacttgtctg atatcaacac ctccttgcaa
    61261 aagtcattca ctttttcctt actcagtatc gttaaacccc aaaaaggaat ttcaatttat
    61321 taatttcaca tcaataatta taacatgggt aaattatcaa gtcatttctt ttctgatttc
    61381 gtaatatatt tctactcgta atcgttgtac aaattgttgc aaatcatgct atcagactta
    61441 gcatttcttt gtttgcttct gcctctgacg catgggcgta taagtccagc agtcttgctt
    61501 tcacttaata cggttttggg cttctgtcgt cctcaatgac ttcgcttagt tggaaatcaa
    61561 aaagattctt ccttacatag tcgtcctcga ttgtcatgta gaatgacgct tttaaggaac
    61621 acttgctgta ttataaaaag cagagttgct tcatattttc ttacgtgtca aaaagcttcc
    61681 aataatcgcc cctataagga caatcggtgt taatctgaca aatagacact caaacgcatg
    61741 aaaagctact ccaaaaacag cggtttcagg gttggtataa ttccaattca agtaaggact
    61801 atttagtcct cctaagacca taaaaactat tactatgact gaacataata aaataaataa
    61861 ccaatgaaac atttttcttc tcatattttt tctttgtaca agttgcaagt ttataatctc
    61921 taatttttca gaaatcactt ttaagttatc aacttccaac tcaacaatag tttctccaag
    61981 taaagtgctt accggcgttt caagtacctc tgatatagaa atcaacatat cagaatcagg
    62041 aactgacaat ccttgctccc atttagatat tgtttgtcgc actacattca attttatagc
    62101 aagttcttgt tgcgaaagtc cttttgactt tctgattgtt ttaatgtttt cgcttaacat
    62161 tagggctaac cacctttctt tcagttgtta ccgatattat aggcaaaact gcttgttgct
    62221 tcaagcaacg cattttaaca ttcaactgaa actcccacgc ctaaaggtgt gtggtttttt
    62281 tagatactac atgaagttct acaatactct taattataat aaatcataac ctacaacata
    62341 ttctcactaa tcatattacc taagactttt attaacaaaa tatctgtcga caccattaac
    62401 attaatatta ggctcgtttc tcaacctata tagtttttat atcttcatac tagatattaa
    62461 tttataacca tttaatttta attcttttaa cctatttatt tctttatcat gtaatatttt
    62521 aaagttatca tatgttttaa cacacaattc tctgttgatt gactttaaat tatcattaac
    62581 attcattatt aaaaatgcat aatagcaatc tctttgaata acatatcttc taagccttct
    62641 atattaaata tttttcttct atatctggga cagaatacaa agtgataatt aattaaactg
    62701 acagttgttt gagttttcta tatttattct ccatatactt atattaacat tatatgtgta
    62761 tgtatcaata ctttttatac actatttatg atatccatac cacatctaaa ggagtgggct
    62821 ttccgaacta ttctgtaaat ttcttatttt tcctttaacc gctttgctta tatatacagt
    62881 gtttatacgg atattctcga tttttaagcg ctttttgtaa taaaaataga tatgtccagt
    62941 aattaaaact gtagaaatat ttataaaggc ataagacaaa tttacctaca atttttagtg
    63001 tttagattct aaaaaataaa aataattata attgagttca taattttaaa acttattgaa
    63061 tataattata tgtcggttaa agacgtatga aaataaaagg aatttataag ttatgtgttg
    63121 tatagatact gtatatgcag catgtaataa atcttagcac tatttatatt ctatacaaaa
    63181 agatatttga agggagatta aaaatgggaa tattagaagg cgctgcaatg ataagagaga
    63241 ttgcaattaa aatagctaaa gaaaaaggta ttacagaaca aaaggcatgg cctgaagcgg
    63301 taaaagaatt taaagaaaaa tatgaacttg tattataaac tttgactgta aaactgtctc
    63361 tattttattg agacagtttt ttatattata acattcatat tatgaagaat aatatatata
    63421 attttagatt ccttgtaact ttaacttaaa gtaaaataat ttagaataaa aacagtatta
    63481 ataaatttta tttgtcatat aaatttgttt ttaatattat tttttaaggt ataaatccta
    63541 tatattagat ataaattttg gaggtatatg atttggataa aaaacttgaa aatagatgct
    63601 catggcaaga atattttatg agactgtgtg aaacagtagc tgaaagagga acttgtgata
    63661 gagcttatgt aggagctata attgtcaatt cagaaaacag aatagtgtct actggatata
    63721 atggtagtat ttctggggat aagcattgta gtgaagttgg tcatgaaatg agagatggac
    63781 attgtattag aactattcat gctgaacaaa atgctcttta ttattgtgca aaagaaggta
    63841 tttcggttaa agattgttct atttatgtaa ctcactttcc ttgtttaaac tgtactaagg
    63901 ctataattca atctggaatt aaacatatat attatagaac tggatataga atagatgagt
    63961 atgctataaa attattgcaa tcgagtaatg tcttatatac aaaattataa ctttaacact
    64021 atttaaataa tattctatat ttttacaaaa taaattataa taaaagtgta agatataaaa
    64081 agaaacaaaa ttctaagtta tgcatatatt aaatagaagt taaatttaat tgtaaaggag
    64141 atgctaattt gaaagtagta ataataccag ggcacacttt aactggaaaa ggtacaggag
    64201 ctgttgggta tataaatgaa agtaaagaaa caagaatact gaatgactta attgttaaat
    64261 ggcttaaaat aggtggagct actgtttata caggaagagt tgatgaatca agtaatcatt
    64321 tagcagatca gtgtgctata gcaaataaac aggaaactga tttggctgtt cagattcatt
    64381 ttaattcaaa tgtcacaact tcaactccag gaggaacaga aacaatatat aagactaata
    64441 atgaaaaaac atatgcagaa agagtgaaca ctaggctggc tacagtattt aaaaataggg
    64501 gcgcaaagtc tgatgttaga ggcctttatt ggcttaatca tactattgca ccagcaatat
    64561 taatagaagt atgttttgta gatagtaaag cagatacaga ttattatgtt aataataaag
    64621 ataaagttgc taaattgata gcagaaggta tactaaacaa atctatatca aattctcaag
    64681 ggggaggtgt aaataaagtg tatgaaaatg taatcgttta tacaggtgac gctgataaag
    64741 tggctgctca gattttacat tggcaattga aggattcttt aataattgag gcgtctagct
    64801 ataagcaagg tttaggtaaa aaagtttatg ttgtaggcgg agaagctaat aaacttgtaa
    64861 aaggtgatgt agtaataaat ggtgctgata gatatgaaac tgttaaatta gcattaaaac
    64921 aaatagataa attataaaat tatgattatt ttataaaaaa taaataagtc aggataaaga
    64981 aaaaatgata agaacaaaag ttgtagagtt aatagcaaca gtatgcagag aaaacaaacc
    65041 acataaatgg gttgatgaaa attatactcc ttatgataaa agtggtaaag ttgaattaat
    65101 gtcaatagaa gatttaaatg agttaatatc aagcaatgga aaagcagatt tactttatag
    65161 ttgtagatta caaaaaattc taaaagagat ttatataaat caaagtagag catcttatat
    65221 gtcaggttgt ggattatttt ggagttcgta ttgggatata cttgaagaaa aatttgaaga
    65281 atggttatat aattcttata tcttttttga tgaagatgat gaatatttag aaggaatgga
    65341 agattttgag cttgaatgta aagatgttct tatggatgta attgaaacaa caagcataga
    65401 tatatatgtt caaatgataa agaggaatat taccaattat taaaaacaca tagtgtcaaa
    65461 ttaagctaat aaaacgacct tataaatact attttaaggt cgtttaaatt atatctctta
    65521 gacttctttt atattaaact tattattttt tatctagaaa aatattttta attatagtca
    65581 atatatcaac tataacatcc atatttgatt taacactgtc tttagtaaca agaaaatctg
    65641 ctgtaacttc agtaactacc tctgttacat ctttcatatt ttctcctact tcgccaaaat
    65701 tttctacaac actcggaaga ttatttaaag ttgtatttat attttgagta ttttcattta
    65761 acatagttcc aacagtattt aaaatcttat gtagtttaac aagtacaata attaaataaa
    65821 ctaaagcaat acaagcgagt atagctaata ataaatatat tatacttata ttaatcgtta
    65881 ttgtattgtt catattattc ctcagtaaca ctaactggtt caacaatatc tattatttta
    65941 tcttcctcac tagaattttc aacacttttt ttgttatcta tatatttttt tatttttttc
    66001 tttgattcta taaagtttcc ttttttattc tctagcttct cagatacttt gccttttaca
    66061 tctacagttt tcatatttat cttttcagca atttgttgtg aagcatcttt tatatcttct
    66121 cttgtctctt ttccagattt aggagccaaa agtactccac tcactgcacc agtaacagct
    66181 cctaatacta caccagctgt agcaatttta gctttcttaa ctttttcagc tctctgttta
    66241 gcttttcttt tatcttctat tttctttgat agattcatgt ttaatcgccc cttattataa
    66301 tatttctaaa cattataata cattttttac cataatgata tagtttctaa ctaaattctt
    66361 aaaaatcaat aaaaattctt tttaattact tactatccat tacaatttaa atttttataa
    66421 ggattttcta tatattttta ttttattagt atataatatg tatcacatat agattataaa
    66481 tatcttattt aattagtttc atgtatataa ctaaaaattt tttagtataa atgaccttca
    66541 atctttctat atagattaaa ttagtatctc aaaaaacaat aagagaggaa ttaatcctct
    66601 ctttttaatt taattagatt tggcagggcg gcgtatcctg catctctatt aactactcta
    66661 tagtagcgta ttgggtgcct tttccaacct caaatctaac taataaatat ctacatgtat
    66721 attaatatta taacctatat gataatattt ttcaatattt tcggggaaat taataatatt
    66781 atgttaacca tcatattgtt ttactcttcc actgtttatt ctactttcta atttcgcttc
    66841 ttttatagca tacattgaag agacatataa atattctttt tttgtatcta attctgtagc
    66901 cactaaaata taatcatcaa ttttttttat aaactccaca cttttcccag gttttttagg
    66961 atgacttcct atatattcag gtgactttaa taccattttt atagtatcta ttatatcatt
    67021 aaaaatatcc ttactcagtt gacatctatg ttttttcttt atatgtttta taacaccaga
    67081 agaagcataa attttaccag tatattcaat tcctgcaagt tctgccgttt cttcatctat
    67141 gattccaaca actttgtctg tagacatata aagcacattc ctttctaaga taatttactg
    67201 ttaatactgt aaaatttatt taaattaaat atccatattt aaagtatagt ttattccaaa
    67261 aagaaaagat agtataatat agttttttca tatatgactt tatataatcc ctttttatat
    67321 aatttataaa tggcaaataa ggttctattt tcaaggtatt tttagaaact gtttaatttt
    67381 tttaagtttt attgagtact cttgcttctt tataaaaata taatctaata cctatattat
    67441 ataaaacgtt ttcttttaaa gttttctgtg ataatattat ttatatataa aataaatttc
    67501 taataggagg aaatcatgaa caatcaacaa caagaagtat ataaaaaatt agatgaatta
    67561 aacatacctt atgaggctgt aaatcatcca ccagtttata caattgaaga aatggaagaa
    67621 ttaaaaacat tacatatgga atttgttgta aaaaatttat ttcttcgtga tgctaaagga
    67681 aaagaacatt ttttagttgt attaggtaaa gacaaaaaag cagatttaaa agatattcgt
    67741 caacaaattg atagtaaacc tcttagtttt gcatcagaag aaagacttca aaaatacttg
    67801 aaacttacta agggagctgt aactcctttc ggtatattaa atgataaaga agctgttgta
    67861 aaagttgtat ttgataagga tttattaaaa atggataaaa taggtataca tccaaatgat
    67921 aatactgcta ctgtattttt aaaatttgaa gatatgaaaa agcttataga agaaaatgga
    67981 aacgaaatat actacgtaga agtataattg caacttaaaa aatggcaaaa gcaatgaatg
    68041 cttttgcctt cttactactg ctgtaatcaa tgctattaat ataatcattt ccattagtat
    68101 aattattttc tacaataatg attatttatg tttacttatc tttttttgca gatacaagta
    68161 gcatcatagg tctacgtagc tcatctttca taccaggaat tgcatctagc agtttttctt
    68221 ctggttgagg ctcaataatt tctaatactt caaatcctgt tttaattaaa gtatttaaat
    68281 aagttgttaa tgttttatga tattttataa cctcttctcc tagaaaattt gacttacgta
    68341 atccttcttc aaaatatcta tctactggcc agtgtagatt attaccatcc ttatcacagt
    68401 gccactcctg acttccatgt gcagtaaata taggatgttc aacagaaaat acaaaatcac
    68461 ctttatttga aagacaatta cttatatttt tacatatatc ttcaaatgat tgaatataat
    68521 gaaatgctaa agaactaata accacatcaa aactatcttt tggaaaatta atatcttcaa
    68581 taggcataca tatgtatttt atattatcaa atgttgtttt gtttctagct tcttttagca
    68641 ttttttctga aatatcaatt ccaacagcag aagttgcccc attctcaact gcatgttgac
    68701 aatgccatcc aaatccacat cctaaatcta aaactctttt tcccttgaaa ttaggtaaca
    68761 tttttctaaa agtatgccat tctccagcac ctgctagtcc atttatagaa cgttccattt
    68821 tactgtattt attaaaaaat ttatcatcat catatttatt ttgtttcata aagctccctc
    68881 cattttaaat atatttattt atcaatactc tatcaaatat aaacttttat cacttttaca
    68941 tgaaataata aaagtttata taaaca
//
LOCUS       DAMKOJ010000009        68746 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000009 DAMKOJ010000000
VERSION     DAMKOJ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 68746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68746
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.009"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..1975)
                     /locus_tag="PC592_000689"
     CDS             complement(<1..1975)
                     /locus_tag="PC592_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
                     /protein_id="HDF4054700.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTGKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSGGSSSSKVGQIKFNATDKQIKMASGDKTVDPSDNTYVLKLTNGTVKDGDVK
                     ANVEVTGLPSGLDYTAVGNKSANTITITVSGTASQALQADLDNVSVLVKAGAVSETTA
                     TDSIANATFEVKKYVAAPAVGQLTFDATDKQIKM"
     gene            complement(2399..3793)
                     /locus_tag="PC592_000690"
     CDS             complement(2399..3793)
                     /locus_tag="PC592_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4054701.1"
                     /translation="MTKLNKKLSISISIVVVVVYIVSITINSMFIHRYYLHEKRNILD
                     NIENEIKDKDIDKLKSDIDSIEEKNNADIVYIELDKNHKDKGNIDRINQDLLNAFWKK
                     GLSLNKFWIEENSLKNIGKKSINKIYNQGKTKYSLLVKFIKKDNYLFAISIPIEHSEE
                     TIGIVNRFNIIMGVFSVVIITILTFILSNRVIKPIEKLKFLSKDISELNFRIEDIKTN
                     DEIEELAYSINMMSEKLEKAHNELNKRNENLKTFISDASHEIKTPIALIKAYAIGMKD
                     GLDDGTYTDTIIEQAENMTNTINSLLYWAKYEKKERSLCLVDLKERLYKSLKNYELLI
                     DKGGISVKCNVDDRELIISSDEDSIEVVFNNLISNAIKYTNNNEIEINLFEENERIIL
                     SIKNGIDCDMEDEIENIWKPFYVLEKSRSKELSGTGLGLTIVRTILEENNFRYRVEIC
                     DKIIAFYIIFIKLI"
     gene            complement(3786..4433)
                     /locus_tag="PC592_000691"
     CDS             complement(3786..4433)
                     /locus_tag="PC592_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4054702.1"
                     /translation="MNILIADDEISMLKILCAYFKKENFNVLTAKNGEEALDIFYKNK
                     IDLAILDWMMPIIDGIEVCKEIKENSNTKVLMLTAKSQSEDEIEALNIGADEYIKKPF
                     DPRVLIIRAKKLVNYKDTINIKDLKIDFESSKVFKGDNELLLTKKELELIRCLINNKG
                     MILSREKLLDLVWGLDYEGDFRTVDTHIRRLRVKIGEDIIKTYRGLGYSLEDFND"
     gene            complement(4868..5707)
                     /locus_tag="PC592_000692"
     CDS             complement(4868..5707)
                     /locus_tag="PC592_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF4054703.1"
                     /translation="MSDIKNEVAKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAISGIV
                     GLF"
     gene            complement(5731..6489)
                     /locus_tag="PC592_000693"
     CDS             complement(5731..6489)
                     /locus_tag="PC592_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4054704.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNENVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6546..7019)
                     /locus_tag="PC592_000694"
     CDS             complement(6546..7019)
                     /locus_tag="PC592_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054705.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNNGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELIAKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(7048..7464)
                     /locus_tag="PC592_000695"
     CDS             complement(7048..7464)
                     /locus_tag="PC592_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4054706.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAVIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLNL"
     gene            complement(7510..8562)
                     /locus_tag="PC592_000696"
     CDS             complement(7510..8562)
                     /locus_tag="PC592_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF4054707.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGTEVKSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDRDGADIVIESAGTPMTCGQVLLLAKKGGTILYAGVPYGDVVLTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSTGLYHMKKGAMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIGN"
     gene            8958..9638
                     /locus_tag="PC592_000697"
     CDS             8958..9638
                     /locus_tag="PC592_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF4054708.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSIKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9768..10088)
                     /gene="sugE"
                     /locus_tag="PC592_000698"
     CDS             complement(9768..10088)
                     /gene="sugE"
                     /locus_tag="PC592_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDF4054709.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            10470..11297
                     /locus_tag="PC592_000699"
     CDS             10470..11297
                     /locus_tag="PC592_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF4054710.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGDLIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGVAICYDIRFPE
                     LSRLMALKGAEIVILPASFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGKIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            12090..12764
                     /locus_tag="PC592_000700"
     CDS             12090..12764
                     /locus_tag="PC592_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4054711.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNSYEVYTAQSGKDALKKISK
                     NPDIILLDINIPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIDNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETIWGV
                     GYKWIK"
     gene            12752..13912
                     /locus_tag="PC592_000701"
     CDS             12752..13912
                     /locus_tag="PC592_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4054712.1"
                     /translation="MDKINNMSLKKVFFVLTLSSLIIASILTTFSYILLNNLYNYIQD
                     KYLKTPINTGFITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIKNLDENISIIAKQEGKSFTLKSQINNVNLL
                     FDENIILRVVENIISNAFRYARNNVSILIYIEQELLTFVIEDDGIGFSKESLKSALRP
                     FYRDKTLNESNAHFGMGLYISKILCEKHGGSISIENNLTNSAKITAKFSTKN"
     gene            complement(14186..15376)
                     /locus_tag="PC592_000702"
     CDS             complement(14186..15376)
                     /locus_tag="PC592_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF4054713.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTVGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSEKGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEQKVILTPEQEERLLAFMEKDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRVLNIDHQLLKDSEMGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILKNRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(15455..15658)
                     /locus_tag="PC592_000703"
     CDS             complement(15455..15658)
                     /locus_tag="PC592_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF4054714.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENLDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(16034..16273)
                     /locus_tag="PC592_000704"
     CDS             complement(16034..16273)
                     /locus_tag="PC592_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4054715.1"
                     /translation="MNNTRPSFYLISSAVDGNVNSIEKILAFYDPYISKCCLRPFYDR
                     YGNVCIVVDMELKGRIREALIKMMLDFDIPLETEE"
     gene            complement(16266..16694)
                     /locus_tag="PC592_000705"
     CDS             complement(16266..16694)
                     /locus_tag="PC592_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4054716.1"
                     /translation="MKPSNFQRTIQCQFDCKLKRVVKGIVRNYRKELKRRRNKEISYC
                     ELPEIVVEKLAVWDEYESDYTAFDVCGIEVRVLDDDLAEAIKYLSEKDREILLMYFFL
                     GMSDTEIGDRLKINRSTSFRSRKNSLEEIKKKLKENMNDE"
     gene            complement(16975..17199)
                     /locus_tag="PC592_000706"
     CDS             complement(16975..17199)
                     /locus_tag="PC592_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054717.1"
                     /translation="MIGLKKRDIKKALKAGAKAGGVSLSDVRADIEATIDEAMNSTDP
                     EVQANFKKYFGNKRPTSEEYIYKITQKTKV"
     gene            complement(17326..19059)
                     /locus_tag="PC592_000707"
     CDS             complement(17326..19059)
                     /locus_tag="PC592_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054718.1"
                     /translation="MKKLKEILFLSDKGYTDLKKAIIACTITNLAMLLPFCITVMVFS
                     ELLNPFLGQELDWQNIWLLWGAGIISAIIVFLASKNDYRKTYIASYKESNVTRLRIAE
                     HLRKLPMSFFNTKDLSELTTNMMSDCSSMESMLSSTIPPLIANGISVTLTCVLLALFD
                     WRLALCVFITLPIAFLVIWCSRKYQIKLFEKQVETKLNASSQVQEYLEGIKIIKSCNL
                     SGVHFRTLNRALLEMKKIAVKVEMVVGIFMSSASMILQAGIGITIFVGTILLVNGQIE
                     LLPLLMFFLIVTKIYGPILAILSQLTTLLNLNVVTERMKTLLTTPAMSGKEETPQTYN
                     IKLNDVSFAYNNEDVIHNVSCTIPQGSITALVGPSGSGKSTIAKLIARFWDIQSGSIT
                     IGNKNIKTINPENLMEKMSFVFQDVTLFNDTVFNNIQMGNPNATKEQVYKAAKVAYCD
                     EFVRNLPNGYDTILGENGSTLSGGERQRISIARALLKDSPIILLDEATASLDPENEVF
                     VQKALAHLIKGKTVIMIAHRLRTVVDADQILVMENGKIVEHGTHNELMERKGLYHKLY
                     SIQQESLGWSV"
     gene            19109..20659
                     /locus_tag="PC592_000708"
     CDS             19109..20659
                     /locus_tag="PC592_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018213172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054719.1"
                     /translation="MFPHFSITSIFLKKTRVVAYCRVSTGSDEQLVSLQAQKAHYESY
                     IKANPEWEYAGLYYDEGISGTKKENRSDLLRMLSDCETGRIDLIITKSISRFARNTTD
                     CLEMVRKLIDLGVHIYFEKENINTSSMESELMLSILSGLAESESISISENTKWAIQRR
                     FQNGTFKISYPPYGYQNIDGQMIINPKQAEIVKYIFAEVLSGKGTQKVANDLNQKGIP
                     SKRGGRWTATTIRGILTNEKYTGDVILQKTYTDSHFNRHTNYGEKNMYLVENHHEAII
                     SPEDFEAVDAILNQRAKEKGIEKRNSKYLNRYSFSSKIICSECGSTFKRRIHSSGTRK
                     YIAWCCSKHISNITECSMQFIRDEDIKTAFVTMMNKLIFGQKFILRPLFHGLRNQNNA
                     ASFRRIEELETKIENNMEQSQVLTGLMAKGYLEPALFNKEKNALEAERERLLAEKDQL
                     TRSVNGNFAKVDEVDRLLKFATKSKMLTAYEDELFEDYVERIIVFSREEVGFELKCGI
                     TLKERLVN"
     gene            20660..21073
                     /locus_tag="PC592_000709"
     CDS             20660..21073
                     /locus_tag="PC592_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054720.1"
                     /translation="MGHTPYGYRIEDGKAVVDEKTSEQVKELFSGYLAGLSLKEAAKK
                     AGIDCYHATAGKMLQNKHYLGDEFYPPIIDEETFEKAREEKRKRAEKLGRIREPKDEP
                     KTDYPVKFKAKPLVQKYEDPYKQAEYAYSLIESEV"
     gene            21077..22648
                     /locus_tag="PC592_000710"
     CDS             21077..22648
                     /locus_tag="PC592_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4054721.1"
                     /translation="MAVSRNVTVIPAIKRVGNNKTSESKPKIRVAAYCRVSTDSEEQA
                     SSYEIQIEHYTNYIKKNKEWELAGIFADDGITGTNTKKREEFNRMIEECMAGKIDMII
                     TKSISRFARNTLDCLKYIRQLKDKNIAVFFEKENINTMDSKGEIMLTIMASLAQQESQ
                     SLSQNVKLGIQYRYQQGEVQVNHKRFLGYTKDENKQLVIDPEGAEVVKRIYREYLEGA
                     SLLQISRGLEADGILTAAGKAKWRPETLKKILQNEKYIGDALLQKTYTVDFLSKKRVK
                     NNGIVPQYYVENSHEPIIPRELFMQVQEEMVRRANLRGRKGGKKRVYSSKYALSSIVY
                     CGHCGDIYRRVHWNNRGYKSIVWRCVSRLEEKGSECTAPTINEETLQTAVVKAINELL
                     ANKEPFLSTLQKNIATVFNEENDNATDDIEGKLEELQQQLLIQAKSKNDYEDVADEIY
                     RLRELKQNALAENAEREGKRQRIAEMTDFLNEQSCELEEYDEQLVRRLIEKVTVFDDK
                     LTVEFKSGVEIDIEI"
     gene            23003..23872
                     /locus_tag="PC592_000711"
     CDS             23003..23872
                     /locus_tag="PC592_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF4054722.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            23853..24587
                     /locus_tag="PC592_000712"
     CDS             23853..24587
                     /locus_tag="PC592_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF4054723.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            24620..25528
                     /locus_tag="PC592_000713"
     CDS             24620..25528
                     /locus_tag="PC592_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HDF4054724.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPAEEKGYSYIILFDDYNKIDLT
                     LLPLEELGNYLNDDKLIKIILDKDGRIQQAVVPTDMDYHIRKPSAREYDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            25525..26067
                     /gene="sat4"
                     /locus_tag="PC592_000714"
     CDS             25525..26067
                     /gene="sat4"
                     /locus_tag="PC592_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HDF4054725.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            26160..26954
                     /locus_tag="PC592_000715"
                     /note="aph(3')-IIIa"
     CDS             26160..26954
                     /locus_tag="PC592_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HDF4054726.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            27230..27802
                     /locus_tag="PC592_000716"
     CDS             27230..27802
                     /locus_tag="PC592_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDF4054727.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            27775..28182
                     /locus_tag="PC592_000717"
     CDS             27775..28182
                     /locus_tag="PC592_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF4054728.1"
                     /translation="MVLNRFCRLRNEYRNFRVDRIKSICIEEELCQSHDGSLEQILKQ
                     MLSYKKLYNVILRAEKGETYNSIKNRYSLGFLEETDLGSKMEIEFQTDSFEILSKQLI
                     EYGSGIEIVQPDELKCITRKHLAQITNHCLNLI"
     gene            28293..28952
                     /locus_tag="PC592_000718"
     CDS             28293..28952
                     /locus_tag="PC592_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RibD family protein"
                     /protein_id="HDF4054729.1"
                     /translation="MKPKIIMHTQISLDGRIKGFDNPEVYYQVAGGIHSDAVLFGSNT
                     VFTAFEKYPAETEADFEKIITSPEDPRPIGVIPDSRGILRSLHCLRNLGYLKEIVILV
                     STATPKEYLNYLEERHYPYIVSGNDHVDYEKAFQILHEQYGCKYMRTDSGGGLTNKLL
                     ENGLIDEISLVISPCFVGNKEKQLFDNLLLSEKVNLELQGTENAEHGCLSLRYAVKNK
                     D"
     gene            29614..29865
                     /locus_tag="PC592_000719"
     CDS             29614..29865
                     /locus_tag="PC592_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054730.1"
                     /translation="MIHVVKIPVKNKTKEVVRITVYCRVSKNIEEQRSGLNSQIAYFK
                     ELSNKVIEIDLAEVYHDVGRSGLIKNGRTSYKKMIVDGL"
     gene            29984..30355
                     /locus_tag="PC592_000720"
     CDS             29984..30355
                     /locus_tag="PC592_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008818840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054731.1"
                     /translation="MSCHSIGHGLNSVSKKVLELYDEGKIEFSVAKDLLYTTRNAVHY
                     CDGNTYEAIACFDGCRCARCLKKTNELYGLYDALDECREYYDIFSNKEDGVLSGDLCK
                     DCFDEICEKHHSIIIEDEVVY"
     gene            30674..31074
                     /locus_tag="PC592_000721"
                     /pseudo
     CDS             30674..31074
                     /locus_tag="PC592_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566808.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(31786..33603)
                     /locus_tag="PC592_000722"
     CDS             complement(31786..33603)
                     /locus_tag="PC592_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054732.1"
                     /translation="MAKKTPKQVKPKTGLARCMELASNKKGLIFISAILSSLASIASF
                     IPYIAVYFIIRSILQVYPNLNSLDVNEVIGYGWLALGGIIANILLYFLAIFCSHLAAF
                     GTLYELKVKFAEHITKIPLGYHLTIGSGRLRKIMDENIESVEGFIAHQFPDFVASVTA
                     PIVMVILLFAIDWRFGIASLVGIILAFIVQFMGYGSGAMKENMGKYQIALEDMNNASV
                     EYVRGMPVVKAFNQTANSFEQLKHAISQYTEWVLKFSLGWQNCMPAFTTIINNIYLVL
                     IPVGILIGTNAVNQKEFLMTFIFYLLFVPAVAGILNKIMYVSESFMQINGNVARMDEI
                     FNIPVLKDTQISKTFDNDNVTFDNVSFSYTGKENELAIKNVSFEAKQGEITAIVGLSG
                     GGKSTIANLISRFWDVTSGSIKIGNVDVREVGTNDLMKHISFVFQDIFLFKQSIFDNI
                     RMGNPNATKEQVISASKAAQCHDFISKLPNGYDTVVGTQGIHLSGGERQRIAIARAII
                     KDAPIIVLDEATAFSDPENEYLIQKAFEKLMQDKTVIMIAHRLSTIRNANKIIVMENG
                     RLIESGKHNDLIQKNGRYAEMWKHYTEAIDLKVQTKVVQ"
     gene            complement(33727..34686)
                     /locus_tag="PC592_000723"
     CDS             complement(33727..34686)
                     /locus_tag="PC592_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054733.1"
                     /translation="MIGMDNRFNKSWYGDKAQLVDSDNDCVIIDYGCKGKGIITSYNL
                     YDGITLCFLDFYTDEIMPSQKFNPDIISIVHCQAGRYECEFSNHQMFYLSEGYFSIMG
                     TKHLPISFSFPLKKCYAFSLVIDKHALSADTQKILNDFCLDMDKISERLKLNKNGYLS
                     HADFELGHLFEEFYNAKDKESITYFRVKAIEFLYFINKLSGNEETEFRYFNKKYIQIT
                     KDVCKYMTEHLEEKVSLEQLAYEKGINLSLLYKVFAQVYGDTPYSYIKKYKMNIASNE
                     LRNSKRKINDIALSLGYSNASKFSIAFQSVYGILPKDYRKAEN"
     gene            complement(34799..35710)
                     /locus_tag="PC592_000724"
     CDS             complement(34799..35710)
                     /locus_tag="PC592_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4054734.1"
                     /translation="MFKKNKKQTETIKEPKEKKVRTVKVGTHKKTVIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELCLQDTNGIENFVKNFAKSYYTWNNSKEAIEARTQA
                     ISGYLTKELQDLNVDTIRTDIPTSSTATNVIVWSIEQSGTNTFSATYEVDQQIKEGEK
                     TSNVKATYTVKVHIDADGDMVIVQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATA
                     FLETFFKLYPTATEKELAYYVSGNVLEPIGRDYLYSELINPIFTKDGENVKVKVAVKF
                     LDNQTKATQVSQYELVLHKDSNWKIIG"
     gene            complement(35727..36734)
                     /locus_tag="PC592_000725"
     CDS             complement(35727..36734)
                     /locus_tag="PC592_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF4054735.1"
                     /translation="MKLKHIALIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITV
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCQNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKYTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLMQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLSNSYWQQHLIGAGRVK
                     Q"
     gene            complement(36731..38941)
                     /locus_tag="PC592_000726"
     CDS             complement(36731..38941)
                     /locus_tag="PC592_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF4054736.1"
                     /translation="MKERIKGAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTANGFSSSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGADRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLFIFNIGITIFVFLLM
                     GIMMLSQILFIIFAMFLPISFLLSMIPSQENLAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISKDYPFFMVAFLQIVCFAGIFIKLGDLMNMFSLNAGDSQNMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQRRQNIADKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTIPKPSVEKMQEVKRPATATTSKISEPVKTSVIKERPLSSGASDRKASQPIQP
                     AHRQNVEKVVSQETHQNYKAERTTKAQTFEQSKRTTEHTEKNRNLVMKKGQKKK"
     gene            complement(38941..41391)
                     /locus_tag="PC592_000727"
     CDS             complement(38941..41391)
                     /locus_tag="PC592_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4054737.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLETNDFGYLIEHLYGRDGVAYEDYEYQLPKKKLRRE
                     TQIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSDSRGLLHVIDELRREDTPVSRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVAKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(41369..41767)
                     /locus_tag="PC592_000728"
     CDS             complement(41369..41767)
                     /locus_tag="PC592_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4054738.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(41877..42380)
                     /locus_tag="PC592_000729"
     CDS             complement(41877..42380)
                     /locus_tag="PC592_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF4054739.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNSMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GMCEIPY"
     gene            complement(42398..42901)
                     /locus_tag="PC592_000730"
     CDS             complement(42398..42901)
                     /locus_tag="PC592_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF4054740.1"
                     /translation="MQETRVLVETRGTTGEETISYWFDLPIDVAEFEEKLGVGAESGD
                     YRIIEKVLAFANEVHEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVFENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(42820..43116)
                     /locus_tag="PC592_000731"
     CDS             complement(42820..43116)
                     /locus_tag="PC592_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4054741.1"
                     /translation="MSDIFKDMQVKVGCEYISDQPSYKRKVWQEMKRLNLADYEERQL
                     EDFSKYVFGMPYQTLKDVMKQQKGREEQCRKQGCWWKREEQLAKKQYHTGSTCR"
     gene            complement(43217..43690)
                     /locus_tag="PC592_000732"
     CDS             complement(43217..43690)
                     /locus_tag="PC592_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4054742.1"
                     /translation="MDYIIREIKKEEYDLLNDFLYNAIYIPDGVEPPPKSIINCPELQ
                     EYVFEFGKRKDDRALVAEVQGNVVGAIWVRIMNDYGHIDNDTPSLAMSVFQKYRGQGI
                     GTSLLQQLLLVEKTSGYSKLSLSVQKNNYAVKMYKKAGFLVVDENSEEYIMTVNL"
     gene            complement(43767..43988)
                     /locus_tag="PC592_000733"
     CDS             complement(43767..43988)
                     /locus_tag="PC592_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054743.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(43989..44123)
                     /locus_tag="PC592_000734"
     CDS             complement(43989..44123)
                     /locus_tag="PC592_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDF4054744.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILNIGKEADYEMKQLEESEDN
                     "
     gene            complement(44135..45331)
                     /locus_tag="PC592_000735"
     CDS             complement(44135..45331)
                     /locus_tag="PC592_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF4054745.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLALASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGRYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEQQAKLTEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(45576..45992)
                     /locus_tag="PC592_000736"
     CDS             complement(45576..45992)
                     /locus_tag="PC592_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054746.1"
                     /translation="MEIKEINKIIQSEDKDEKSKSVKCICINYGDFLADCEGFVQKRY
                     HDFKCNPKHQFEKKADTILENAIHEKNFMPDLFLIRLNRKQSACNSQIDFVFELLDKS
                     FLETDPIRKSEISEETLNLCLSADVSFIMVYIGMNR"
     gene            complement(45996..47378)
                     /locus_tag="PC592_000737"
     CDS             complement(45996..47378)
                     /locus_tag="PC592_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4054747.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     CTDWEHFSLLENDLTLSPYNFITILIATGACVLVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGSLKLMNNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGRLAQERQ
                     VMPEQQGKEN"
     gene            complement(47479..47805)
                     /locus_tag="PC592_000738"
     CDS             complement(47479..47805)
                     /locus_tag="PC592_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054748.1"
                     /translation="MDLNIVLAVICGAVALVGAFCVVFQIYHMTVIDATARGLKHPKF
                     WGVFTMSGNNSSGLLMYLIGRRKYPIVNMSESNSKELEKRKKSAGVGLLFLAIGVIGI
                     ICATLI"
     gene            complement(47821..48228)
                     /locus_tag="PC592_000739"
     CDS             complement(47821..48228)
                     /locus_tag="PC592_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4054749.1"
                     /translation="MEIGKKLKNARVQSGMTQENVAEKINVSRQTISNWENEKSYPDI
                     ISVIELSNLYSISLDVLLKGDEKMIEHLEESTNVVKSNQKMIWAIIVNIIVVALLITL
                     NMFIPDNRYFLVGIFCLMVITSSALLYQIIKKF"
     gene            complement(48395..48778)
                     /locus_tag="PC592_000740"
     CDS             complement(48395..48778)
                     /locus_tag="PC592_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF4054750.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGSPQNHTPQGQSKK"
     gene            complement(48794..49120)
                     /locus_tag="PC592_000741"
     CDS             complement(48794..49120)
                     /locus_tag="PC592_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF4054751.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKKFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            complement(49355..52399)
                     /locus_tag="PC592_000742"
     CDS             complement(49355..52399)
                     /locus_tag="PC592_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF4054752.1"
                     /translation="MKKMLKRLCTGFLALATVVTALPTTPVHAESKQYWTESKERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFRNGYKTRADASTRMSADQISDVA
                     LSIEYVKQYTDSHSGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFSGARAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKASSNTSITDGNG
                     NYSIAGATYGVFADKDCTKQLATLTTDENGNTDVAEVKAGTVYIKELSAPAGYKVDKT
                     VYSLKVEAGTTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDGDGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQAGDKSEQIKGLYVTQITEDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNENAVLVEGKLYKKNEVVKTIR
                     TDIEGITSTSADLLPYGKFRIVESEAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGENHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVVDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENTELIIDGKRVENDYTFVADDEEMKVEISYTFNASALGGKNLVTFEELYD
                     FSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTFIDTVT
                     LEGLEVGTQYKLVGWQMLREENAELLINGKRVESDYTFIADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPETPPTPEKPN
                     RPSDSPKTGDNTNLYGLLALLLTSGAGLAGIFFYKRRKMKKS"
     gene            52766..53434
                     /locus_tag="PC592_000743"
     CDS             52766..53434
                     /locus_tag="PC592_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054753.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSIIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHSEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            53437..55905
                     /locus_tag="PC592_000744"
     CDS             53437..55905
                     /locus_tag="PC592_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4054754.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITLGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLIGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGASENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRGIGAEPNQIYKIVILQILILCTIAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTSISLI
                     FSFISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSILDKIDNM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSTLEDFK
                     NGSICFIKNPLAISTPGVKTKYTNLKPKDNITINKKQLDIYSTVDKMFFLQGNGWVNG
                     VDIIVYDSVYNTLTNKNKFNQINIYAKDKSDLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIELLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAILGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISILAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(56146..57570)
                     /locus_tag="PC592_000745"
     CDS             complement(56146..57570)
                     /locus_tag="PC592_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4054755.1"
                     /translation="MKNQSLATQFRRTFIFIIIASIVATVITYVFAFYLFIYSLNKDI
                     YPPNYYERQVPRIKKYIDEKNIALLSQSNEEGLKRTIRGDGMLYQVVDDNGNILYGNN
                     PKKPFKTKEELFNNFINTTVRKGGYIYTVPIKGTNGKIEGAVILFYQVKMTFANSMGR
                     LTFAVIVIAMFSPFLYVIGFTIWLSKQFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKNSLSAQWKMEQERVEMVEALAHDLKSPLSIVLGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNPVPINLPEFLVQ
                     KVQDYELQAHQKDVELILKMYGNIQSPIQIDLDRLTRIFDNIISNSLQYTPSGGNISI
                     IAKAEKNCISYEICDSGSGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(57589..58281)
                     /locus_tag="PC592_000746"
     CDS             complement(57589..58281)
                     /locus_tag="PC592_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4054756.1"
                     /translation="MSKILIIDDEIDLVMLLEDELKAKGHEVLIAYDGQAGIELSKNE
                     PDLIILDIMMPKMDGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFEKLCLYMKERAIKIDGKDIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(58333..59112)
                     /locus_tag="PC592_000747"
     CDS             complement(58333..59112)
                     /locus_tag="PC592_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF4054757.1"
                     /translation="MIKLLSSEWLRAKRTAVQGLTLYMPIIFSLCVVAYLTIKSGSTQ
                     EFAFEGFFTIWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMNIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGAKVWAFVPWTWPVKLGMLPGTYFIKEAGTISTEV
                     FYSKMMQSATVVFIVVAIGLIIFLIGGVIWFKIWEGRKSYE"
     gene            complement(59109..59879)
                     /locus_tag="PC592_000748"
     CDS             complement(59109..59879)
                     /locus_tag="PC592_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF4054758.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QINSWAWESLLALIFNWWSMMFLSIGFALFATLVASQEKKAGNYRALRTHNVSPMTIW
                     INKIIAMAVYSFISTLVLIVVTIMTGLILKAGPIPFGQIIGASIVCWVGSLAILPIQL
                     WLATWKGMFLSMGVGALGMIFGVLAASKPFWVAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(59876..60580)
                     /locus_tag="PC592_000749"
     CDS             complement(59876..60580)
                     /locus_tag="PC592_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF4054759.1"
                     /translation="MKDLIIETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTDGRIIFDRKPWKRESLEKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLNDPELLILDEPTNGL
                     DPFGIQELRELIASFPEKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            61358..61615
                     /locus_tag="PC592_000750"
     CDS             61358..61615
                     /locus_tag="PC592_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054760.1"
                     /translation="MILNRTELFRGYSLDRFNEICNILSVNKIKYKYKVKNNTYSKKP
                     FYNEITLGNLGQKEDFSYEYLIYVHKDDYEQAEALINSKLR"
     gene            61758..62384
                     /locus_tag="PC592_000751"
     CDS             61758..62384
                     /locus_tag="PC592_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HDF4054761.1"
                     /translation="MKINIKSTLNEFIKQNNLFDDNRIISYLPNITIDTDKIKTIMIN
                     EVVPTNTNDDFYSIDKDADYLKTTIPLFNNAGIEVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            62755..63141
                     /locus_tag="PC592_000752"
     CDS             62755..63141
                     /locus_tag="PC592_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4054762.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            63144..64943
                     /locus_tag="PC592_000753"
     CDS             63144..64943
                     /locus_tag="PC592_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HDF4054763.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSNTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDILNILLLILWIIGILIMIVITIHCNIKIKSMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNRDMLINYIMCFFQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDNHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNKQTMYEDLSKYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRDNSHIPWDGKHHSNISWNEDQDLFSAMENS
                     VNWYFQTLDKKTGIKNIQTYLEQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFNFEDKNIETVKDSLLISKKDGVSLSGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGISASKITLSILNDKKIYNP"
     gene            complement(65296..67392)
                     /locus_tag="PC592_000754"
     CDS             complement(65296..67392)
                     /locus_tag="PC592_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDF4054764.1"
                     /translation="MIKVVYMRKNKKARKMIIFGFLMCLLIVIIVFLAKFILDGLNKN
                     KPDEVFKQYMSFANKKQYEKMYDLLDEKSKSENKKEDFVLRNKKIYEGIDAHNISIKI
                     NDIKKNKNNDKLINYDSKMDTLAGEILFSNEVLLTRDRQKNYKIKWQSSVIFPELEED
                     NTVRVSKLKGKRGRILDRNGVMIAGQGLASMIGLVPGKMSDNIEDLKKLSTLLNVSVE
                     QIEKKLNASWVKENSMVPIKTIEKIKENPDGTVKEEDKELQESLLSIPGVKISNTEVR
                     VYPFGEKTGHLTGYVQNVNAEILKEKEGKRYNANSIIGKIGLESLLEDRIRGIDGYEI
                     IIADRYGDKKETLVTEPKVDGEDVKLTMDSKLQSKLYDQMKNDKGCAVVMNPKTGEVL
                     SLVSSPSYNPNEFILGMSEDRWNELNKNENKPMYNRFKARLCPGSSFKPVTAGIGITT
                     GKINPNENFGHSGLSWQKDSSWGSYKVTTLKDYGNTVNMENALIYSDNIYFAKAALKI
                     GEDVLSKELLKLGFDESMPFEFGLSSSKFGTDNKFETEIQLADTGYGQGKLLVNPVHM
                     ASIYSAFVNDGDMIKPHLEFKKNLQAEFWKKGVFSKEAVKIIRDDLLQVVESPNGTGH
                     SAMIKGIRIAGKTGTAEIKASKDDVTGTELGWFNAFTVDGNNDKQYLAIAMIEDVKSR
                     GGSHYVMPIVKSVFED"
     gene            67753..68331
                     /locus_tag="PC592_000755"
     CDS             67753..68331
                     /locus_tag="PC592_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4054765.1"
                     /translation="MPTKGEQTKQFIIDTSIMLFSEKGYSNVTMKDICEACNLSRGGL
                     YRHFNSPKEIFISILNTHKHYSQNLLDKGIKENISAKHMLEYFFQQQKADINGKYCGF
                     DFAIHEFAFIEKDQRDYMNKRYSSAITMLSNLIDYGQSKSEFKKCDSKSVAIHIMFLF
                     DSMKTSASILKLTNKDIDNQIKIIKDMVILYE"
     gene            68324..68626
                     /locus_tag="PC592_000756"
                     /pseudo
     CDS             68324..68626
                     /locus_tag="PC592_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895500.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
     gene            68604..68741
                     /locus_tag="PC592_000757"
     CDS             68604..68741
                     /locus_tag="PC592_000757"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054766.1"
                     /translation="MMIIRLSPEPPMTKVTEFLLHRILHTKICLTNSPQAIPIVPTVL
                     T"
BASE COUNT        21999 a        12662 c        10996 g        23089 t
ORIGIN      
        1 ccatttttat ttgtttatct gttgcatcaa aagttaattg acctactgct ggtgctgcca
       61 catatttttt tacttcaaat gttgcatttg caattgaatc tgtagcagtt gtttcagata
      121 ctgctcctgc tttaactaac acacttacat tatctaaatc agcttgtaat gcttggcttg
      181 ctgttcctga tactgttatt gttattgtgt ttgctgattt atttcctact gctgtataat
      241 ccaatcctga tggtaatcct gttacttcaa cattagcttt tacatctcca tcttttactg
      301 tcccatttgt taattttagt acatatgtgt tatctgatgg atctactgtc ttatcacctg
      361 atgccatttt tatttgttta tctgttgcat taaattttat ttgacctacc tttgatgaag
      421 aacttcctcc actacctcct ccatgtgaag aacctccact tgatgaactt cctcctgaag
      481 agttagaact tggactattt ccacttattg ttggagaatt atctccctta acactactta
      541 ttgtaccttt attatctata gtagtccctt tagaattatt tgtaactgta gttatctttc
      601 caccattagt cacttttact tgacttgctc cagatgctac tgttaaacta ccaatctcac
      661 ctttagaatt attctctatc ttagctccat ttttatcatt aacctttaag ttggttatct
      721 ttccatagtt aacaaaagtt ccatctttta catcatctat aactacatca tccacttttg
      781 catagttatt tacatcacca ttaggcatgt tgatagtcac agtctttgta tatgtaccat
      841 ttaagtttac tgttactgct ttatcagttt gtattgtaaa tgcttcttta acctcactag
      901 ttggcttaaa gtttataaca tcattagcag tagctttatc tatagctgat tttaattcag
      961 aaattgtttt agcttcaact gtttttactt cttgtagtga tttcatttca ttaaatgctg
     1021 tctcattacc atttccacca actttagtta tcttatcaaa actcttagag ttaactagag
     1081 atttttgtga agctgataag ttctttccaa ctaaaactac tggtgattga tttttagcac
     1141 ctaatacacc tactgctagt gcatctataa gttggtcttg tttattcatt ccatctttag
     1201 ttacataagc attttttaaa tctgtctttt tataaaattc ttttattact tttgcatttg
     1261 tatcatttct atctgttccg cctagtcttg tactatttgg tagtttattt ttaacagctt
     1321 cagaaattga actctctcca cctactacat aagattgagt tattccagca tcttttataa
     1381 atttgtctgc aactgctgtt ccatttttag aatcagcaag tattactggc atattgtttt
     1441 gtgcagctgg tgctcctaca cttacagcat ctgcaagtcc tttttcacca ttaactacag
     1501 ctattttctt aacatcactt atagcatcta atttctttgc caattctaag gatgtttgat
     1561 atctctcagc tccagagatt ctttcaaaag atatttttaa atcttttatt tctttttcta
     1621 tgtttgtgct taatacagaa gttccaccta ttaagtatac ttttttagct tttaatcttt
     1681 gtatttctgc tttcgtctta tcatttaatt tatctttacc tgttaaaagt attggagcat
     1741 tttttgcctt tgcaaatggt gttgcagata gagcatctgc tatagatgag tcgtttacta
     1801 ttactacctc atcagcattt ttccatccat cttgacttat tttaacagca gtttcatatc
     1861 tttcttgccc tgttaaattt gttgccacag tttgtgcact agctatgcct gctgttgaac
     1921 ttccagctat cattgttact gtaagcattg cagcaatctt ctttggtatt ttcattgtat
     1981 tttcttcccc cttgtccatt tgatattact taatttttta actttgttcc cgttctaatt
     2041 ctaaaggata cttaatatct aattttaaag aggtttctaa ctataatgat ttcataatta
     2101 atttgtaatt attttgatac attgcagtca ttatataagg aataaagaaa tttttttatt
     2161 gattgaaaaa tttgtaaatt tatattttaa ggtaagtttg atttttatgt taatgaattg
     2221 ttgtaaaaag tagggtttca cataaaaaag tagcctttag aattaaaagt gctactcttt
     2281 ttacaaataa attttattat ttatacttgt aattatatat taaataacca attttatcca
     2341 tatgaaaaac aaataattgc tatatttttt taattattct ttatatttgc attttaattc
     2401 aaattaattt tataaatata atataaaatg ctataatttt atcacaaatt tcaaccctgt
     2461 atctaaaatt attttcttca agtatagttc taactatagt aagaccaaga ccagttccag
     2521 aaagctcctt acttcttgac ttctctaaaa cataaaaagg cttccatata ttctctattt
     2581 catcttccat atcgcaatct ataccatttt ttatggataa tataattctc tcattctctt
     2641 caaaaagatt aatctctatt tcattattat tagtatactt tatagcatta ctaattaaat
     2701 tattaaatac cacctctata ctatcttcat ccgaacttat tataagttct ctatcatcta
     2761 cattgcactt aacacttatc ccacctttat ctatcaacag ctcatagttt tttaagcttt
     2821 tatataatct ttcctttaaa tctaccagac acagacttct ctccttcttc tcatattttg
     2881 cccaatataa aagagaattt attgtattgg tcatattctc tgcttgttca ataattgtat
     2941 ctgtataagt cccatcatcc aagccatctt tcatacctat tgcatatgct tttataagtg
     3001 ctattggagt ttttatttca tgagatgcat ctgatataaa agtttttaga ttctcatttc
     3061 ttttattcaa ttcattatgt gctttttcaa gcttttcgct catcatgttt atgctgtaag
     3121 ctaactcctc tatttcatca ttcgttttta tatcttcaat cctaaaattt aattcagata
     3181 tatctttaga taaaaacttt aacttttcta taggttttat gactctgttt gataatataa
     3241 acgtaagtat agttattata actactgaaa aaactcccat tattatatta aatctattta
     3301 caatgccaat agtttcttca gaatgttcta tgggtataga tatagcaaac aaataattgt
     3361 cctttttaat aaattttaca agtaaactat attttgtttt accttgattg tatatcttat
     3421 ttatactttt cttcccaata ttttttaaac tattttcttc aatccaaaac ttatttaaac
     3481 ttaacccctt cttccaaaat gcatttaata aatcttgatt tattctatct atattacctt
     3541 tatctttatg atttttatct aattctatat atacaatatc tgcattattt ttttcttcaa
     3601 ttgaatcaat gtctgatttt aatttatcta tatctttatc tttaatttca ttttcaatat
     3661 tatccaatat atttcttttc tcatgtaaat aatatctatg aataaacata ctatttatag
     3721 ttatagacac tatataaaca actacgacta ctatcgatat acttatggac aattttttat
     3781 tcagtttagt cattaaaatc ctccagacta taccctaatc ctctataagt ttttattata
     3841 tcctctccta tttttactct taatcttctt atatgagtat ctactgttct aaaatcaccc
     3901 tcataatcta aaccccatac taaatctaaa agtttttctc tagataaaat catcccctta
     3961 ttatttatta aacaacgaat taattctaat tctttcttag tcaataatag ttcattatca
     4021 cctttaaaaa ctttacttga ctcaaaatct atttttaaat ctttaatatt aattgtatct
     4081 ttatagttta ctagtttctt agctcttatt attaaaaccc tagggtcaaa tggtttttta
     4141 atatattcat ctgcaccaat attgagtgct tctatttcat cttcactttg acttttggca
     4201 gtcaacataa gtacctttgt attactattt tcctttatct ctttacaaac ctctattcca
     4261 tcaattattg gcatcatcca atctaatatt gctaagtcta tcttattttt ataaaaaata
     4321 tctaaagcct cttccccatt ttttgcagta agtacattga aattttcctt tttaaaatat
     4381 gcacaaagta tcttaagcat actaatttca tcatcagcaa ttaatatgtt catttattca
     4441 catccctaaa attcattatt atatttaata ttatatccat tactttaatt atataaaata
     4501 tatgttacag gaagtttaca actatttata atacattagt tatatattat aatacctcga
     4561 caatatcttg attatatatt ttaatatgta actaatatat tataatattt taattgtata
     4621 aatttatatt tttgtgaaat tacttaatat tttatatgaa aatgaaaaag cacctcattc
     4681 tgattaaaaa tctttctgag atacttttta aaatattaaa tactaaatat agcttatata
     4741 agcttaaatt ttaatctatt ataaaattac cctaattgct aaacttttta ccataagttt
     4801 tcctacatct tacaaatata atcaatagat gtagaatcat aatttacaca ccaacatata
     4861 tatttattta aaataatccc acaatacctg aaatagctcc cactactatt aatataaaca
     4921 ttatttttat tggagaaagt cctttcttta aggcaaaaag tactaataat gtaagtacca
     4981 aaggaattaa tcctggaaat atcttatcaa gtaaatccgt ttgaaggcta aatttaaaat
     5041 ctccactagt ataacttatt ggtgtagaca aattaataaa cctacctaca agtcccccca
     5101 tgactaaagt acctagtata gaagcacctt ctataacctt atttactatt ccaccttgga
     5161 gtatactttc aacagctttt ttcccatact tatatccatt cgtccacatt ccaaaagaaa
     5221 ttgaagtcat tattatatat tgagctatta caaataatat aggccctgca attgatgctc
     5281 ctccctcagt taaaccaata caaacagcta atactatagg agttataact ccttgagtta
     5341 aagtatcacc aatccctgct agtggaccca tcaagcctgt tttgatagca ttcataccat
     5401 ctccacttat ttcatctgct ccattagctt tttcttcctc catagctatt gttattccat
     5461 gtataacaca tccacatata ggctctgtat taaaaaatgc tagatgagtc tccacttctt
     5521 gttttagctc ttccttatct ggatataact ttttaagtac cggtaacatt gaatgtgaaa
     5581 aagctgttga ttgcaatctt tcataattgt aattagattg tgcaaagaaa aaccatctta
     5641 accacgattt tattacatct ttcttgctta acgttttctt agctacttca ttttttatat
     5701 ctgacataat attttccccc tcacatgtat ttaagatgta gcactatctt ttccgtactt
     5761 aattgaagta attgtaagag caagtattac tccaataaca gatattacta ttatatctac
     5821 tttaaaataa acagccatta gtattcctaa tatgaaaaag ggcatagtaa atttgtttcc
     5881 aatcaatttt aaattcatag caattccaag tgctggcaac atagccccaa ttacattaaa
     5941 tacatgtaac acattctcat tcattacttc caacatacca tctatcgcat ttggaccaaa
     6001 ataaacaact aatagtgctg gtataaagct cattgcaaat aacagtatct gtggtggtac
     6061 tatatttata aatgctactc tatcaacatt ccctttttga acctctctat cagcccaatg
     6121 tgcaaaaaaa gaatttactg tcatctttcc aatccaaagt acagttgcaa cagttcccaa
     6181 tggtacagct attgccattg cagtacttac atctagctta gatgctatag ctaaagcagt
     6241 gcctacatat cctgcaaaag ctgggtctcc catctgagct cctcctgctg atataaaacc
     6301 tagatatatc atatttatac ctgctcctat aattgctcct tgaacagggt ctcctaatat
     6361 aattcccgtt acaaatccag ccaatagagg tctattccat gtaaaaaatc caacataagt
     6421 caaccatgga ctccaagaaa gataataaaa aattgctatc aatactgctt gaattagtga
     6481 aatatgcata cttttcctcc ttattttctt ctaaagattt acaagataat cttctttata
     6541 aagctttata ataatgttcc tacatcaatt ttctttgcat ctggtactat ttgtataaag
     6601 catttaacat cctttgctat tagctctcga aatatttctt tttcttcatc tgacacagat
     6661 atatttttat aaaaactttt tctaccaagt ccagctccca tacctccaac attcaattcc
     6721 tttaaatcta ccccattatt tactaaacct aaaacagttt taggatattt gaccaatact
     6781 attaaatttt catctccatt atgtgatttt aaaacttcag cacctgattc tacatcatgt
     6841 acttcaacct taacagttga tggagctgcc atttgtaaaa cttgaactat aaatgggtcc
     6901 tttactacta aatcgtccac gattactatc ctttttgctg atgtaatctt acaccaagca
     6961 gtaataactt gcccatgtat taatctatca tcaattcttg ttaatgctat attactcata
     7021 ataattcctc cagattttta atttattcta taaatttaaa acagttttaa catctttgat
     7081 tcctgatatc ccaacttcct cacataaatt cttcaagtct ttcaacttca tagtatctct
     7141 gtttaaaaat aattctaaaa gcataggtaa atttacacct gtcaaacatt ctaactcaca
     7201 taccttagca aatttattta ttataacagc agatgtatta aatggagtcc caccataaaa
     7261 atcaagcaat actaaaactc cttcatcctt atatttctca attccatctt ctaactttct
     7321 actaaactca tctatgctat caccatggtt taatcctaaa gtctctacat tctcctgttt
     7381 acctactatt agttcagcac tttctaacat cgctttagcc atatttccat gtgtagctat
     7441 aattattcct gccatatgaa tcataccttt cttaactaaa cttttttata tggattattc
     7501 tttagtactc taattaccta tattaatcat tatcttacca aagaaaatat cccttttata
     7561 tactttttca aaatacgctg gtacttcttc taaatttatt ctatgtgtta ctaatttttc
     7621 aacattcata gcaccctttt tcatatgata cagtccagta ctccattctt ttcctggaaa
     7681 tggaaaggag tttccaaacc aagttccctt tacagttaat tcacttctta ctatcttttc
     7741 aaattgttct ctagtcaaaa ctacatcccc atacggtaca cctgcataca atattgtccc
     7801 tcccttttta gctaacaaca acacttgacc acacgtcatt ggagtaccag ccgattcaat
     7861 aacaatatct gcaccatctc tatcagttaa cctttttatt tcttctacaa tattcttttc
     7921 ttttgcattt atacaaatat ctgcccctaa ctcttttgcc aagtctaact tctcatcaaa
     7981 tacatccaca gctattattt ttgtcgagcc aaatatcttt gcccattgta ttgaaaataa
     8041 tcctattgga cctgttccaa gtactacaac agtatctcca actttagctt ctgacctaaa
     8101 aagaccatgt cctgctatac atactggctc tagtgcagca gcagtttcat aacttatctc
     8161 atctggtatt tttattaaat ttctctcttt tacctttgta tactctgcaa aacaacctcc
     8221 aagttcttta tttcctatta ttgctacgtt attacatctt gaatacaatc cttttttaca
     8281 ttcatcacat tcaaaacatg gcatggctgg acaaacagca actctatctc ctattttaaa
     8341 gcttttcacc tctgtaccaa cctgtgctac ttctccagaa aattcatgcc ctaaaatctc
     8401 tccaaccata tgtggacctg tctttgaata ttttgatata tcagagccac atattccagc
     8461 tacttttact ttaattatta catcatcttt ttctaatatt tttggtacat ctacatcctc
     8521 cactcttgtg tctcttatac catagaatct aactgacttc acgattaacc acccctactt
     8581 tttatttgag aatatatact tattttttat atgttaaata tctaaagcaa ctttcatgcc
     8641 aatatatgta agtattgttt tcatgcactt tataaaatta tcattagatg tgtgtcaaag
     8701 tgtgtcaaaa cttttttata cgaaaactta tgtgtgtcaa tataaacgac actcacattt
     8761 tatactagtt ctcctattat aagttttata aaatgtactt tttttgttat ttttataaaa
     8821 ttgttcggaa attccccctc tatttgtgat ataatattaa atataaggta tcaatataaa
     8881 ttttcatacg aatatcagaa cttttttgac actaatgcct tattcaatat aataatttaa
     8941 ctttttggag gttgtttatg aaaaaagtgt atcaaggaaa gactaaagat gtttttgaat
     9001 tagataatgg aaattactta cttaaattta aagacgatgt aactggtaaa gacggagtat
     9061 ttgacccagg cgaaaatagt gtaggtctaa gtatagatgg aattggtaga gctaatttag
     9121 agacatctat taagttcttt gaaattctaa acaatgctgg aattaaaact cattatgtaa
     9181 gtgctaattt agaagaggca actatggaag ttctaccagc aaaagttttt ggtaatggat
     9241 tagaagttat ttgtcgttat agagctgttg gtagtttctt acgtcgttat ggttcatgtg
     9301 ttgaagaagg agctaaacta gattgttacg tagaagcaac tttaaaagat gatgaccgtt
     9361 gtgaccctct tataacatct gaaggtttag aagctttaaa cattatgact caagctcaat
     9421 ttgattcaat gaaaagcatg actcaaaaaa tttctaacat agttcgtgat actatagctg
     9481 aaaaaggtct tgaactttat gatatcaaat ttgaatttgg attctacaat gatgaagtaa
     9541 tcttaataga tgaaatagca tctggaaata tgcgtgttta taaagatggt gtaatagttg
     9601 accctatgga tttaactgct cttttattag ataaatagta tatacatata aatttcaaat
     9661 ataataaact tataaataag ataagctatg aagtaaagac tttttaaatg ttgattattt
     9721 ttaaacattt tctcgccttt aatttcatag cttatttaaa ttatactcta attggtagac
     9781 aataacttta accctacaat tcccaccaca ataaaaccta tacatgcaat tcttgatata
     9841 ctaataggct catttaagat agccatgcct acaatagctg taccaacagt accaattcca
     9901 gtccatattg catatgaagt tccaagtgga agatgtttta gtgctaatga caaaaaataa
     9961 aaacttacaa tcattccaac aacagtaagt atacttggag ttaatttaga aaatccatgt
    10021 gaatttttta gttgaaaagc ccaaaacact tcaaacaaac ctgcaacaaa taaaaataac
    10081 catttcataa actcatccct cttttcaaat atatctctta tttttccaat aaaataacct
    10141 gagaaatatt ataaaatatc tcccaggttt ttgtccttcc gtgttcacaa caaaaactat
    10201 gttgtgggtt ttatctcgga ccagaccaat cattaataat tgcggaaccc tataaaactc
    10261 tattaattat tctattttat ctataataat actatcaaca tatataaaaa aagtcaatat
    10321 atgggttcca tctataataa aaataacttt tatatacctt ttaatattct tattcacttc
    10381 tctccatacc catttaggtc aatctaagaa tatctaattt ttatttaata tgttataata
    10441 acataaaaat attgaaagga gtaatttcta tgaatttcta taaaattgca gtatgccaga
    10501 tgattactac agaaaataaa attgaaaata tcaatcatgc tgtagatatg gtaacagaag
    10561 ctgccatcaa tggagctaaa attgtagttt tgccagaaat gtttaactgc ccatatgaaa
    10621 ataaatattt tcctaaattt gctgaagaat atccaggtga aacaacaacg atattgagta
    10681 aattagctga gaaacatgga atttatttag tttctggtag tattcctgag ttagaagatg
    10741 gaaaaatcta taatacttgc tatgtatttg ataaaaatgg agatctaatt ggaaaacatc
    10801 gtaaaatgca cttatttgac attgaagtta caggaaaagt tagttttaaa gaatcagata
    10861 ctcttacagc tggaaatgat gtcactgtaa tagatactga atatggaaaa gttggtgtag
    10921 ctatttgtta tgatattcgt ttccctgagt tatcacgttt aatggctctt aaaggtgctg
    10981 aaatcgttat cttacctgct tcatttaata tgactactgg tcctgcccat tgggagttat
    11041 ctataagaat gcgtgcttta gataatcaga tattctatgt tggtgctgca cctgctagaa
    11101 atatgaatgc ctcctacata gcttttggca attcaagaat ttcagaccct tggggaaaaa
    11161 tcattgctca agctgatgaa aaagaatgta ttatttatgc tgacattgat agagatttaa
    11221 ttcctgacat aagacaacag ttaccacttc ttaaacacag aagaactgat ttatatgaac
    11281 ttaatacttt gaaataaaac agaacataac cccataaatc ataaattaag tgttaaaaaa
    11341 atttatgggg ttctcattaa tttgatttaa aattaatttc ataaaaataa tactaatatt
    11401 aatttaatta aataatacta ataatactaa tgattatgct aattatcagt atttactaat
    11461 ttaatcacta ttagttattt cttttattaa atatatttac tttttttact tattatgtct
    11521 tctagcttta catttggatt atggcatctc tttctacttt tagtcacatc tttctattga
    11581 attacttgct taaaacacca atacatacat gccagacaat gttcacaatt atgtaaaaat
    11641 cttgctctac cttattcaat gttgatatta tctctcctaa aatttctttt aattaaaaaa
    11701 caacattcgt tgatatatcg agtatgtttt aagcaactga aaaaaacaat aataattgat
    11761 atatcaacta attaatgtag attaattcat ttttataatt tatatacttt ttaacctttt
    11821 taattaaatc cttcctttct atttatccat tttaaactta aattataaga tttcatcagc
    11881 tgtgtttttg cattccaata agtattaaat atcaaatata tattctatta aaatttctaa
    11941 taatttcatc cttgatttat ttaacatata aaaatatact aactttaatg attaagtttt
    12001 gaaatataac taagaatttg agaatttatt gagattttta tactaaagta tacatactat
    12061 acaaacttaa tttagaaggg agcattctta tgaacaataa aatactcgtc gtagatgatg
    12121 aggaaggtat aataacactc ttaaaagatt actttgaaat gaatagttat gaggtttaca
    12181 ctgctcaaag tggaaaagac gcattaaaaa aaatatccaa aaatccagat attattctac
    12241 ttgatataaa catccctgaa atagatggaa ttgaagtttg taatagaatt agagattatg
    12301 tatcatgccc tattctattt cttacagcta gaattgaaaa tactgacaag ataaatggtt
    12361 ttcgtgctgg tgctgatgat tatattgtaa aaccttttga tttagacgaa cttggagcta
    12421 gagtatctgc ccatttaaga cgtgaacaaa ggaagtcaaa tcaaactaaa attaaatttt
    12481 ataatgattt aacgatagat tacgaaaaaa ggttaatttg tatagataac aatcagattt
    12541 cactttcaaa aaaggaattt gatatagtag aacttctctc tatgaatcct ggacaagtat
    12601 ttgataaaga aaaaatctat gatagagttt ggggatacaa tagcaatgga aatagtgatg
    12661 ttataatgga acacattaga aagatacgaa tcaaactatc aaaacatact cttgaaaatt
    12721 atatagaaac aatctgggga gttggttata aatggataaa ataaataata tgtcattaaa
    12781 aaaagttttc tttgttctta ctttatcttc actaattata gcatcaatac ttactacttt
    12841 ctcatacatt ttgcttaata atctatataa ttatatacaa gataagtatt taaaaacacc
    12901 tataaatacg ggttttataa ccatagttca aaacaatgtg aaccaattta gtgattatga
    12961 taaaacgtta cttaatataa tcaacatact tcagcttgta cttccactta tattttttat
    13021 aggactttta ttattagctg atataatttt ttacaaggta aaactaaaaa cacccataga
    13081 aatactcaat aaaggtgcaa tggaaatatc caacaacaat ttagactttt gtttagaata
    13141 taataataat gatgaattag gtaatctatg taatgctttt gaaaaaatga ggtctgaact
    13201 aaataaaaac aacataaaga tgtggactat gattaatgat agaaaacaac ttaatgctgc
    13261 tttttctcat gatttaagaa atcccctaac agttctaaaa ggttactcaa actatttaac
    13321 aaaatacata ccaacaggca agcttagtga tgagaagatt ttatcaacca cacagcttat
    13381 gtctgagcat attaacagaa ttgaatacta tgtagaaaat atgagtaatg cccaacgatt
    13441 agaagactta gttgtttcaa aatctatgtc aaatataaac aagtttataa aaaacttaga
    13501 tgaaaatata tctatcattg ctaaacaaga aggaaaatct tttacactta aaagtcagat
    13561 aaataatgta aatctattgt ttgatgaaaa tatcattctt agagtcgtcg aaaatataat
    13621 atcgaatgct tttagatatg ctagaaataa tgtatccata cttatatata ttgaacaaga
    13681 acttcttacc tttgtaattg aagatgatgg tataggattt agcaaagaat ctctaaaatc
    13741 agctttaaga cctttttata gagataagac tttaaatgaa agcaatgcac actttggtat
    13801 gggtctttat atttcaaaaa tattatgtga aaaacatggt ggctctattt ctattgaaaa
    13861 taatttgact aacagtgcta aaattactgc taaattctca acaaaaaatt aaagcaatat
    13921 taaatcaatt ttttaggctt tcactcctct tttataaact ttataactta gagtttacaa
    13981 agtgtttttt tgaaataaat tttttgtatc aaaaacttac taaatttctg attatctttt
    14041 cataagttgg taaatgccga tatatcccgt attttagggc tttatcggta ttttcttttc
    14101 ggaagatacc ttgcataagc tggcatttac cagcatgaaa atgcaaccaa aagtagtaaa
    14161 tgagtagtaa atataagctc cgatattaac aagccagtct ttccagttct gcttttgcag
    14221 attgaaatgt accgtgtgcg taatagccaa gtgtcatggt tatgttagcg tgtcccatga
    14281 ggtattgcag agtgtttggg ttcattcctc tgtttgccat attcgtacaa taagtatgtc
    14341 tgaatgaatg tggcgtgatg ttcggtaact tgtccgtgtg atacttgtta tacttcttaa
    14401 tcagtcctcg caccatgccc tcatagtttc ctgcaacttt aggcaagccc tcacgattta
    14461 ggaataggaa attgctgtaa ccacctacaa tcagcggttg tgcctttcct ctgttcttta
    14521 gtattctttg gattgcttga taagcccgtt ctgtcaatgg aagttcccgt tttccgtttt
    14581 tggtctttgg cgtttcaata tagtaaccca tttcgctatc tttcaataac tggtggtcta
    14641 tattgagtac tctgttctgc atatcaatat gcgtcgtcag tccgcaaaat tcagaaatac
    14701 gaagtcccgt ttccagcaga agcacaacct catcataata cttactataa attttgtcct
    14761 tttccataaa ggcaagcagg cgttcttcct gctctggtgt aaggataact ttctgttcgg
    14821 tatcatcttc cagaacatca cttagcttaa attcaaatgg gttctttctg atacagtcgt
    14881 cttgtatcgc catgtaaaat gacgctttca aggaacgctt atagttatca atcgttttat
    14941 aggcatatcc tttttcactc attctaatag cccattcttt agcgtccgac tgcttaaccg
    15001 tatcaatcgc cctcataccc aatgggtcat ttttcagagc gttcataaga tactgtcgtc
    15061 ctttttcagt agcccttttg atgttctttc tttggctgtt cttcttgtcg tagagctggc
    15121 agactgtcat tttaccgccg actgtgtcga taccgtcgtt aaggtctttt tttatctgtg
    15181 cttctttttc cctcaacgat atatcatcac gctttccagc aggtgtcttg tctgtcggta
    15241 caagtttcca agaatagata aattgtggct ttccgtatat atcggtatat ttataaacgt
    15301 atcttccgtc ttttcgctgg ctctctccat tacgcaaatt gcgattttta ctgtcttttc
    15361 gtttcacatt agacatagtg taaagctcct ttccgtcatg gaatgagccg tgatacgcta
    15421 taccttatta taccatatct acggctcaat gacattagat ttcgtccaat gtatctatga
    15481 ttttttcaaa ttgttttcgc ttaatctgaa tacgattacc gttcacgata acccagccag
    15541 cgtcaagatt ttcttcggct aatttacgca atttcttttc gccaatacgg aagtatttag
    15601 acgcttcttc aatcgtcagc gtatattttt cccagatagg cacatcagta ttgttcataa
    15661 tctatacacc ccctttactg tgtgtcgttt tttacaagca ggcagacggc tttggaaagc
    15721 tccgttagta tctcaactat tcccattctt gtgggcagaa ccgcaccatg cggacgtatc
    15781 attattctgt gaggataggt cgtggcaaaa cgacttttcc aacagtcgct ctcggatcac
    15841 tgcgtgggtc gctcgctttc tttttgaaaa ggtcgtggcg tacagtcccc gtggctcgct
    15901 atctcacaaa cgtatctgtc tgctttattc agttgtcaaa gagctgtggc gaaagcgtgt
    15961 tgctttcatg taaaagcagg agcagagcag gaaagagggg attgaacaaa tcatgctctg
    16021 cggttactgc ttcttattct tcggtttcta aaggaatatc aaagtccaac atcattttga
    16081 taagtgcttc tctgatacgt ccctttaatt ccatgtctac gactatgcag acattaccat
    16141 atctgtcata gaatggacgt aaacaacatt ttgatatgta cgggtcataa aatgccagta
    16201 tcttttcaat cgaatttacg ttgccgtcca cagccgacga gataaggtaa aatgacgggc
    16261 gtgtgttatt catcattcat gttctccttt aactttttct tgatttcttc aagtgagttc
    16321 ttcctactgc ggaacgacgt tgaacggtta atctttaatc tgtcgccgat ttctgtatcg
    16381 ctcatgccta agaagaagta catcaacaag atttctctgt ccttttcaga cagatactta
    16441 atcgcttctg ctaaatcatc atcaaggaca cgaacctcaa taccgcatac atcaaaggcg
    16501 gtataatcgc tttcatattc gtcccagaca gccagctttt ccacgacgat ttctggaagt
    16561 tcacaatagg aaatttcctt atttcttcgt cgctttaatt ctttgcggta attacggaca
    16621 atgcccttta ctacacgttt gagcttgcaa tcgaattgac attgtatcgt tctttggaag
    16681 ttcgacggtt tcatatcatc acaccccctt tccgttatga cgtgaaaagt gtttatccct
    16741 ctttccgcac catatctgta cggcaaggtg tgatttgttg caggaatttg aaaaaaattg
    16801 aaaaaatttt ttcgggtaca aaaaaagccc gcacaaaaca tatagtttta tacgagctat
    16861 taaagctgta aaatattcag tttttaataa aatgctatta ggtagtgtat gattgtatag
    16921 aatttcgctt aaaatgttcc ataatacaat cccccttaca gcacttgttt tgtattacac
    16981 ttttgtcttt tgggtaatct tgtaaatata ttcttctgat gtagggcgtt tatttccaaa
    17041 atacttttta aaatttgcct gcacctctgg gtcggtgctg ttcatagctt catcaatcgt
    17101 tgcttcaata tccgcccgaa catcagacaa tgatacaccg ccagcttttg ccccagcttt
    17161 caatgctttt ttaatatctc gttttttcag accaatcata tgtgtgtttc tcctttaagc
    17221 ataaacatct tgaaaagcaa gttatgatat tgtaaatcat tgaaaattta atgtttctgc
    17281 tcttataata ctatttttct attctatatc agtttttcta tacgattata cagaccaccc
    17341 cagactttct tgttgaatag aatataattt gtgatatagc ccttttcttt ccataagctc
    17401 attatgtgtt ccatgttcaa ctatttttcc attttccatt actaatatct ggtctgcatc
    17461 taccacagtc cttagacggt gtgcaatcat aataactgtt ttacctttta tcagatgtgc
    17521 aagtgctttt tgtacgaaaa cttcattttc tgggtcaaga gaggcggttg cctcgtctaa
    17581 aagaataatc ggagagtctt ttaataaagc tcttgcaata gaaattcttt gacgttctcc
    17641 acctgacaat gtacttccgt tttctcctaa aatagtatca tatccatttg gcagattacg
    17701 aacaaattca tcacagtaag ctactttggc agctttatat acttgttctt ttgtagcatt
    17761 aggatttccc atttgaatat tattaaaaac tgtatcatta aacaatgtaa catcttgaaa
    17821 gacaaaggac atcttttcca ttaaattttc aggattgatt gttttaatgt ttttattacc
    17881 aatcgttatt gaaccgcttt gtatatccca aaatctggca atcaattttg cgattgtact
    17941 ttttccgctt ccagacggac caactaacgc tgttatgctt ccctgtggta ttgtgcatga
    18001 aacattgtga ataacatctt cattgttata agcaaaagat acatcattta acttaatatt
    18061 ataagtttga ggtgtttctt ctttcccact catagcagga gtagtcaata atgttttcat
    18121 tctttctgta acgacattaa gatttaataa tgtagttaat tgagataaaa tagctaatat
    18181 cggtccatat atctttgtta caatcaagaa aaacataaga agaggtaata gctcaatttg
    18241 tccattgact aataagattg tccctacaaa tatagttatt cctattcctg cttgtaaaat
    18301 catgcttgca ctggacataa aaataccgac aaccatttca actttaacag caattttttt
    18361 catttccaat aacgctctgt tcaaagtcct aaagtgaacg ccgcttaaat tacatgattt
    18421 aatgattttt attccctcta aatattcttg tacttgactg gacgcattta attttgtttc
    18481 cacttgcttt tcaaataatt ttatctgata tttcctgcta caccaaataa ctaagaaagc
    18541 aatcggtaat gtaatgaaaa cgcataatgc taaacgccaa tcaaatagtg caagaagaac
    18601 acaggttaaa gttacagaaa ttccatttgc aattagaggc ggaatagtac tacttaacat
    18661 tgactccata ctactacaat ccgacatcat atttgttgta agttctgata aatcctttgt
    18721 gttgaagaaa ctcataggaa gtttacgcag atgttcagca atacgcaatc tagtaacatt
    18781 tgactcttta taagaagcaa tataagtctt gcgataatca tttttggaag ctaagaaaac
    18841 aatgattgct gaaataatac ctgctcccca aagcaaccag atattttgcc aatctaactc
    18901 ttgccctaaa aaaggattta atagctcact aaaaaccata actgtaatac aaaacggaag
    18961 taacattgct aaatttgtaa tcgtacaagc aatgattgct tttttcaaat cagtatagcc
    19021 tttatctgat aaaaataata tttcttttaa ttttttcatt ttactgcacc acctttgttt
    19081 gaactttcaa atcaatcgcc tctgtataat gtttccacat ttcagcataa cgtccatttt
    19141 tttaaaaaaa acacgagtag ttgcctactg tcgagtttct acaggcagtg atgaacaact
    19201 tgtcagcttg caagcacaaa aggcccatta tgagagctat ataaaggcta atccagaatg
    19261 ggaatacgca ggcttatatt atgacgaggg tatcagcggc acgaaaaagg aaaaccgctc
    19321 tgacctactt agaatgttat cagactgtga aactgggaga attgacttaa ttattacaaa
    19381 gtcaattagc cgatttgcca gaaatactac agattgcttg gagatggttc gaaaactgat
    19441 cgaccttggg gttcatatct attttgagaa ggaaaacatc aatacgagtt caatggagag
    19501 cgaattgatg ctctccattt taagtgggct tgcagaaagt gagtcaattt ccatttccga
    19561 aaatacgaag tgggccattc aaagacgatt ccaaaacgga acctttaaaa tttcctaccc
    19621 accatatggg tatcaaaaca ttgacggtca gatgataata aaccccaagc aagctgaaat
    19681 tgtgaagtat atttttgcag aggtattatc gggcaaaggc acacagaaag ttgcaaatga
    19741 tcttaatcaa aagggtatcc cttcaaaaag aggtggtcgt tggacagcta ctacgattag
    19801 agggattctg accaatgaaa aatatactgg cgatgttatt ttgcaaaaga cttatactga
    19861 tagccatttt aacaggcaca ccaattatgg tgaaaaaaat atgtatctag tagaaaacca
    19921 ccatgaggca attatcagcc ctgaagattt tgaagctgta gatgccattc tcaatcagag
    19981 agccaaggaa aaaggaatcg aaaaacgcaa cagtaaatat ctaaaccgat attccttttc
    20041 tagcaaaatt atctgctcgg aatgtggcag tacctttaaa agacggattc attcatctgg
    20101 tacaagaaaa tacattgctt ggtgctgcag taagcatatc agcaatataa cggaatgttc
    20161 catgcagttc attcgagatg aagatataaa gactgcattt gttacgatga tgaataaact
    20221 catattcggt cagaagttta tattaagacc actttttcat gggttacgta accaaaacaa
    20281 tgcagcgagt tttcgtagaa ttgaagagtt ggaaactaaa attgaaaaca acatggagca
    20341 gagccaagta ctgacaggtt taatggccaa agggtatctg gaacctgctc tgtttaataa
    20401 agaaaagaat gcactggagg cagaaagaga aaggcttctt gccgaaaagg atcaacttac
    20461 tcgttccgtc aatggcaatt ttgctaaagt agatgaagtt gaccgtctgc ttaagtttgc
    20521 cactaagtcc aaaatgctca cagcttatga ggatgagttg tttgaagatt acgtagagag
    20581 gattattgtc ttttcacggg aggaagtagg ttttgaatta aaatgtggaa tcacattgaa
    20641 ggaaaggttg gtgaattaga tgggtcacac accctatgga tatagaattg aagatggaaa
    20701 agctgttgtg gatgaaaaga cttctgagca ggtaaaagaa ttattttccg gatacttggc
    20761 aggcctttct ttgaaggaag ctgctaaaaa agctgggata gattgttatc atgccacagc
    20821 aggtaagatg ttgcagaaca agcactacct aggcgatgaa ttttaccctc ccattattga
    20881 tgaggagaca tttgaaaaag ccagagaaga aaaacgaaaa cgagcagaaa agctcgggag
    20941 gataagggaa cctaaagatg aaccgaaaac ggattaccct gtaaagttca aagcaaaacc
    21001 tctggtgcaa aaatatgaag acccatacaa gcaggcggaa tatgcctaca gtttgataga
    21061 aagtgaggtg taacaagtgg cagtgagtag aaatgtcaca gtgattccgg caattaaacg
    21121 agtcggaaat aataaaacta gtgagagcaa acccaaaata cgagtggctg cttactgtcg
    21181 tgtttcaacg gatagtgagg agcaggcttc aagttatgaa attcagattg aacattatac
    21241 aaactatatt aagaaaaaca aggaatggga attggcaggg atttttgcgg atgatggtat
    21301 cacaggtaca aataccaaaa agcgtgaaga gttcaaccgc atgattgagg aatgtatggc
    21361 aggaaaaata gacatgatca ttacaaaatc catcagccga tttgccagaa acacgttaga
    21421 ctgccttaaa tacatccgtc agttaaaaga taaaaacatc gctgtattct ttgaaaaaga
    21481 aaatatcaac accatggatt ccaagggtga aattatgctg actattatgg cttcccttgc
    21541 ccaacaggaa agccaatcct taagtcagaa cgttaagctg ggcattcagt atcgatatca
    21601 acaaggtgaa gtccaggtca accataagcg tttccttgga tacaccaagg atgaaaacaa
    21661 gcaactagtc atcgaccccg agggtgcaga ggttgttaaa cggatttata gagagtacct
    21721 tgaaggagct agtcttttac aaatatcaag aggactagaa gcagacggta ttcttacagc
    21781 ggcaggcaaa gccaaatgga gaccagaaac actaaaaaag atattgcaga atgaaaagta
    21841 catcggtgat gcccttctac aaaagacata tacggttgat ttcctttcta aaaagcgggt
    21901 caagaataac ggcatcgttc cccagtatta tgtagaaaac agccatgagc cgattattcc
    21961 aagggagctt tttatgcaag ttcaagaaga gatggttcga agagcaaatc ttcgtggccg
    22021 caaaggcggt aaaaagcgag tctatagcag caagtatgct ttatcgagta ttgtttactg
    22081 cggacactgc ggcgatattt accgacgggt acattggaat aacagaggct acaagtctat
    22141 tgtttggaga tgtgttagcc gattggagga aaaagggtct gaatgcactg ctcctaccat
    22201 aaacgaggaa acattgcaga cagcagtggt caaggctatt aacgagcttt tggctaacaa
    22261 agaacccttc ctctcaacct tgcagaaaaa catagctact gtatttaatg aagaaaatga
    22321 taatgccacc gatgatattg aaggcaaatt ggaagaatta caacaacagc ttcttataca
    22381 agcaaagtcc aagaatgact atgaagatgt ggctgatgaa atttaccgcc ttcgagaatt
    22441 gaagcaaaat gcacttgcag agaatgcaga gcgtgaagga aaaaggcaac gaatcgctga
    22501 aatgactgat ttcttaaatg aacaatcctg cgagttggag gaatatgatg agcaattagt
    22561 aaggcggctt attgaaaaag ttacggtatt tgatgataag ctcactgttg aatttaaatc
    22621 aggtgttgaa atagatattg agatatagga tatcagaaat ggcgaccaat tgagaggtgt
    22681 tacttccttg attggtggct tttcttattt acggattgac tttgactgtg aatatacgta
    22741 taataatatc aacaatgttg ttgatattat tattaataag gagtggacaa catgattgat
    22801 gtaaatgagc tattttagca aaatgaatgg taatttaaag gctattgaaa agacttcatc
    22861 taatcagcag aggtataaaa agacaattga taagttttaa ctatcttttg tgaaattaaa
    22921 aaaattataa atatgttgag tagaagcaaa agatttggct tggaattttt acagcagtga
    22981 atcgataaaa ggagcatgct tgatggtaga taatattatt aaatcagtag cagagaaatt
    23041 atcctctctg tcttatatag aaggtattgt tttaggtggt tcacgtgcaa ggggcaccca
    23101 tacagaggat tcggatatag atatcggcat ctattacaat tcagaatcat ttgacataaa
    23161 tactattaat caattcgcta caaagctgga tgatgagcat agaaataacc ttgttgtacc
    23221 tcccggagca tggggtgatt ggattaatgg cggcggatgg ttagtcataa acgggtatca
    23281 tgtggattta attttacgtg atattaaacg tgtggaacaa ataatgaaag atacagagca
    23341 cggaattgtt actgccaatt atcagactgg gcatccccat ggttatatta gtgcaatgta
    23401 tcgaggagaa ttagcgatta gcaaaatact atatgctaag aatgaaagct tatgcgaatt
    23461 aaaaaaacag gcagaaactt atcccaatgc tttgcagaaa agtttagtta acttttttat
    23521 gtttgaagca gggttctctt taatgtttgt aaaagcaaat tcgggaacag acgataaata
    23581 ttatattgcg ggtcatgttt ttcgtatagt ttcatgttta aatcaagtgt tatttgcatg
    23641 taataatgct tattgtatca acgaaaagaa agctataaaa ctgcttgaaa cttttgaaca
    23701 taaacctgaa aaatataccg agaaggtaaa tcatattttt gaagtactcg gtatctcact
    23761 ttttgaatgc tacgacatga ccgagaagct ttataatgaa gtgaatgaaa ttgtatcgga
    23821 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
    23881 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
    23941 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
    24001 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
    24061 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
    24121 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
    24181 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
    24241 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
    24301 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
    24361 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
    24421 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
    24481 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
    24541 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
    24601 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
    24661 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
    24721 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
    24781 gtttatatct aatgatgact ggcttaatca atttgggaat attataatga tgcaaaaacc
    24841 ggaggatatg gaactattcc cggctgaaga gaaaggctac tcctatataa tactttttga
    24901 tgattataat aaaatagacc ttaccttatt gcccctggaa gagttgggaa actacctgaa
    24961 tgacgataaa ttgataaaga ttattctgga taaggatgga aggattcagc aagctgtagt
    25021 tccgaccgac atggattatc atataagaaa acccagtgcc cgggaatacg atgactgctg
    25081 caatgaattc tggaacacca ctacctatgt ggttaaggga ctgtgccgta aggaaatttt
    25141 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
    25201 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
    25261 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
    25321 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
    25381 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
    25441 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
    25501 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
    25561 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
    25621 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
    25681 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
    25741 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
    25801 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
    25861 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
    25921 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
    25981 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
    26041 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
    26101 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
    26161 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
    26221 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
    26281 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
    26341 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
    26401 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
    26461 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
    26521 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgcttag
    26581 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
    26641 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
    26701 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
    26761 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
    26821 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
    26881 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
    26941 atgaattgtt ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag
    27001 acatctaatc ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt
    27061 tctaaaagtt cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt
    27121 ttgtgagtat ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa
    27181 gaacgcatag gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat
    27241 taacagagta acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga
    27301 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
    27361 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
    27421 cctacttccg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
    27481 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
    27541 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
    27601 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
    27661 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
    27721 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
    27781 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
    27841 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
    27901 aaacaaatgc tttcatataa aaaactatat aatgtaattc ttagagctga aaaaggggag
    27961 acatacaatt ctatcaagaa caggtattct ctcggcttcc ttgaagaaac cgatttggga
    28021 agtaaaatgg aaatcgaatt ccagacagat tcctttgaga tattgagcaa gcagctgatt
    28081 gaatatggat caggcattga aatagtccaa cctgatgaat taaaatgcat aacccgtaaa
    28141 cacctggcac aaattacgaa tcactgccta aacttgattt agagaaagcg attggtctgt
    28201 tatgtatttt ttgtaaggtt tcatatcccc tgctgacata cagctgtcag tgtattatga
    28261 tattctacta tcaaaaagga ggattgaaaa atatgaaacc aaagataatt atgcacacac
    28321 aaattagcct tgatggccgc attaaaggct ttgataatcc ggaagtttac taccaggttg
    28381 ccgggggaat tcattcggat gcggtgctgt ttgggtccaa tactgttttt actgcatttg
    28441 aaaaatatcc tgctgaaaca gaggctgatt ttgagaaaat cataacaagc ccggaggacc
    28501 ccagaccaat aggagtcata cctgacagca gaggtatctt gagaagtctt cattgcttaa
    28561 gaaatcttgg atatctgaag gaaattgtca ttctggtatc aactgccact ccgaaggaat
    28621 atttgaatta tttggaggaa aggcattacc catatattgt gtcaggaaat gatcatgtgg
    28681 actatgaaaa agcctttcag atcctgcatg agcaatatgg gtgtaaatac atgcggacag
    28741 acagtggcgg tggattaacc aacaaattat tagaaaacgg acttattgat gaaatcagtc
    28801 ttgtgatatc accatgtttt gtaggtaata aagaaaaaca actatttgat aaccttctgt
    28861 tatctgaaaa agttaatttg gaattgcagg gaacagagaa tgcagaacat ggctgtctgt
    28921 cattgcgcta tgctgtgaaa aataaggatt agtgcagcat actttaaaaa gtgtctgttg
    28981 ggacagtgtc ctaaaggaag cataagctca tggctagcgg cggtgttaaa gtaacggcac
    29041 tcggccccaa tatatagttg atatgcccct aagcctttga gggcaaggcg gtcaaccgcg
    29101 ccttttccgg tccgcataca gtcgttcaat gagggtatca agctcggcaa tgcggcggtg
    29161 cttctcggtg gttcgtttct tcgccgccgt tttcggctaa ttctaattga tccgaactgt
    29221 aaggataagc aattatccgg ggctagttaa gtatcttaga gaggaagata aagataagta
    29281 aaccaatttt aaagttgtac cgaataaagc cttcaagagg acaacatgct tttgaaggct
    29341 ttattgctta caattacttg gattgtaacg caaaagcagg caccaaatca atgaaaaata
    29401 gcctatccag gcgactgttt cagaaatatg ggcttccgcc aaggggatac cagtggggtg
    29461 cgacatcttt tttgcccact caaggcatgt agagtccatt gttctgttgc gaaaaagata
    29521 aaaaatcaaa tcagttttat agagatgtaa gttgttgatg ataacttgca tctttttcat
    29581 atgttaagat tggagtgata aggatgataa aaaatgatac atgtagtgaa gataccagtt
    29641 aaaaataaaa cgaaagaagt agtaagaatt acagtatatt gtagagtaag taaaaatata
    29701 gaagaacaac gttcaggttt aaatagtcaa attgcatatt ttaaagaact ttctaacaaa
    29761 gtaatagaaa tcgatttagc tgaagtgtat cacgatgttg gaagaagtgg gttaataaag
    29821 aatggaagaa caagctataa aaaaatgatt gtagatggat tataaggcaa atttgattac
    29881 attattacaa aatcagttag taggtttata ataaagcatt gtagtaaaat aaaaaaatat
    29941 gatatattta gattagtgat aataaaaaaa aggagctaaa aatatgagtt gtcatagtat
    30001 tgggcatgga ttaaattcag tgtctaaaaa ggtattagag ttgtatgatg aagggaaaat
    30061 tgaatttagt gttgcgaaag atttattata caccacaaga aatgctgtac attattgtga
    30121 tggaaatacg tatgaagcga ttgcatgttt tgatggatgt agatgtgcta gatgtttaaa
    30181 gaaaacaaat gagttatatg gtctttatga tgcattagat gagtgtagag agtattatga
    30241 tatttttagc aataaagaag atggagtatt atctggtgat ctttgtaagg attgttttga
    30301 tgaaatttgt gaaaaacacc attcgattat catagaagac gaagttgtat attaaaaaag
    30361 ttttactcga taatgggtaa atcttcaact tttagcggaa ttattagcag atagtaataa
    30421 tatacctatg atatttgtga agtttaatct tatattttca ataagggatt actatacaca
    30481 ttgcttatct cttttaatct ttgattcacg ttgagagtgt tgtcttgatg tcaagggttc
    30541 agaagtaaca tgtgaaaaag gcttgaaaat aggtcatttt aaaaatagat tgtaattttt
    30601 aagtacattg aaatcacgaa aatgcttgta aatcagggca tggaaacata tcaatacgga
    30661 cagtggagtt gacagagtag taaccaaaat tgaaggtgtg aactggtctt ttagcgataa
    30721 aatgtttgtc tactttataa atgatttaga gatgtatagt aagtgggaat attcaggtga
    30781 aagtgagttg cttatgttgg aatataaaga gggcatacta tcttttgata atataatgca
    30841 attctattta gataaaatga tgcgggataa ggttattgat tcaattcctt cattttttca
    30901 gcagttactt agaatctgta aaaagtttaa agcattaaaa gacattagta acgcatttgg
    30961 aagggataaa ttaatccaag taactaaaga aaatatttta ataatattcc atcaagtctg
    31021 gcaaaggtat ttatacaggg aaaatatttc tgtattcaaa actatggaaa atgagctgta
    31081 tacaattttc aaaggaatga aatggaacag ttttatgaat aaaataaaag tattcgttca
    31141 gaagccggaa gtaaaatata tcaatctgta acctttgcaa tggtggaagc atattggaat
    31201 aaggataaaa gtattataga taagcagggt tgagaggaag agtctgagta tggaccagat
    31261 taatagttga actatctaaa cataaattgg cagatttcgg aatagaattt actattgtaa
    31321 atctttaaaa tatgcgtcag ttttatcttg cttttccaaa aactacgtat tgtgtcgcga
    31381 attgagttgg acacattatc gcttgcctat gcgagtggag aaaccccgtg aattttaacg
    31441 aataaattta ctccaccatt atgtaatgaa aatacttttg tcatggtgta taaggccttt
    31501 attttactgt atgtggagtc atagcattgc tatgtagagt tgaaaagcct gataaacaaa
    31561 ggctttcttt tatttatgtc tactcaaaaa tactgctttc atttgtattt taataaaaaa
    31621 ttatgttatg ctcgatatgg aataaaaaac acatttaaaa tggaatagga gaatgtcaag
    31681 atgaagatta atataagtac cattatagag gcgattgaaa tggcagatga taattttaca
    31741 ttttttttat ctgataaaaa taatatttct tttaattttt tcattttact gcaccacctt
    31801 tgtttgaact ttcaaatcaa tcgcctctgt ataatgtttc cacatttcag cataacgtcc
    31861 atttttctgt attaaatcat tatgttttcc actttcaatt aagcgaccat tttccataac
    31921 aataatttta tttgcattac gaattgtaga aagacggtgt gcaatcataa tgacagtttt
    31981 gtcttgcata agtttctcaa aagccttttg tatcaaatat tcattttcag ggtcgctaaa
    32041 tgcagttgct tcatctaata caatgatagg ggcgtcttta ataatagctc ttgcgatagc
    32101 aattctctgt cgttctccac ctgaaagatg tataccttgt gttccgacta ctgtatcata
    32161 tccgtttggt aatttagaaa taaaatcatg acactgtgcc gctttagaag ctgatatgac
    32221 ttgctctttt gttgcgtttg gatttcccat gcgaatatta tcgaaaatac tttgcttaaa
    32281 aagaaatata tcttgaaaca caaagctaat atgtttcatt aagtcattag ttccaacttc
    32341 acgaacatca acatttccta ttttaatgct tccagaggtt acgtcccaaa aacgagaaat
    32401 caaattagca atcgtacttt ttccaccacc agataagccg acgatcgctg ttatttcccc
    32461 ttgctttgct tcaaaagaaa cattttttat tgccagttca ttctcttttc cagtataaga
    32521 aaaactaaca ttatcgaatg taacattgtc attatcaaaa gtctttgata tttgtgtatc
    32581 ttttaagact ggaatattaa atatttcgtc cattcttgca acatttccat tgatttgcat
    32641 aaacgattct gaaacataca taattttgtt aagtataccc gctactgctg gaacaaagag
    32701 caaatagaag atgaaagtca tcagaaattc tttctggttt actgcattag taccaattaa
    32761 aatacctacg ggtataagca caagataaat attgttaatt atcgttgtaa atgcaggcat
    32821 acaattttgc caacctaatg aaaatttcaa tacccattct gtatattgag agattgcatg
    32881 ttttaactgt tcaaatgaat tagctgtctg attaaaagcc ttaacgactg gcatacctcg
    32941 tacatattca acagacgcat tattcatatc ttcaagagca atttgatatt tccccatatt
    33001 ttctttcatt gccccacttc cataacccat aaactgaaca ataaaagcta aaataatacc
    33061 aacaagagaa gcaatgccga atctccaatc aatagcaaat aataaaataa ccataacaat
    33121 cggagcagtt acggaagcca caaaatcagg aaattgatgt gcaatgaaac cctcaacact
    33181 ttctatattt tcgtccatga tttttcttaa ccgtccactt ccaatcgtca aatgataacc
    33241 taaaggtatt ttggtaatat gttctgcaaa tttaaccttt aattcataca atgttccaaa
    33301 agccgcaaga tgagaacaaa atatcgccaa aaaatacaac aaaatatttg cgataattcc
    33361 acccagagcc aaccagccat accctattac ttcattgaca tctaagctat tcaaatttgg
    33421 ataaacttga agaatagaac gaatgatgaa gtaaactgca atataaggaa taaatgaagc
    33481 aatcgacgct aaggaagaaa gaatagcgga tataaaaatc agtcctttct tatttgaagc
    33541 cagttccata catcgtgcca agccagtttt aggctttacc tgttttggcg ttttctttgc
    33601 cataataaat cctcctaact aaaaaatgat gtagttagct cttgctaaca tacatcattt
    33661 tactttttat atttatttgc ttctactcca tagctatata tctatccaaa aaatagccca
    33721 aaagtgttaa ttttctgcct ttcgataatc tttaggtaaa ataccatata ccgattgaaa
    33781 tgcaatagaa aatttacttg cattactata tccaagactt aacgcaatat catttatttt
    33841 acgctttgaa tttcttaatt cattagacgc tatattcatc ttgtattttt ttatgtaaga
    33901 ataaggagta tctccatata cttgtgcaaa gactttatac agtaacgaca agttaattcc
    33961 tttttcataa gctaattgtt ccagagatac tttttcttct aaatgttctg tcatatattt
    34021 gcaaacatct tttgttattt gtatatattt tttgttgaaa tatcgaaatt cagtttcttc
    34081 attgcccgac agtttgttga tgaaatataa aaattcgatt gctttaacac gaaaataggt
    34141 aatactttcc ttatctttag cattataaaa ttcttcaaaa agatgtccta actcaaagtc
    34201 tgcatgactt aaatatccat ttttatttaa ctttaatctt tcacttattt tgtccatatc
    34261 taagcaaaaa tcatttagaa ttttttgtgt atctgcacta agggcgtgtt tatctatgac
    34321 taagctaaat gcgtaacatt tttttagggg aaaggaaaaa gatataggca aatgtttagt
    34381 ccccataata ctgaaatatc cttctgacaa ataaaacatc tgatgattag aaaattcaca
    34441 ttcataacgc cccgcttgac aatggacaat agaaattata tcaggattaa atttttgtga
    34501 gggcataatt tcatctgtat aaaaatcaag aaaacaaagt gtgataccgt cataaagatt
    34561 ataacttgta ataatacctt ttcctttaca gccataatct ataataacac aatcattatc
    34621 actatcgact aattgtgctt tatctccata ccaagattta ttaaatctat tatccatacc
    34681 aatcatctct ttttgttaat ctattctaat tttaatatta acatatatct gaaacgtgag
    34741 caacgttttc tgcttttagg gtaaaggggg ctatcttttt ttgataaccc cttaatactt
    34801 atcctataat cttccagttg ctatccttat gtagcacaag ctcatattgc gatacctgcg
    34861 ttgcctttgt ctgattatca aggaatttca cagcaacctt gactttcaca ttctccccgt
    34921 cctttgtaaa gatagggttt atcagttcag aataaaggta atctctgccg ataggttcaa
    34981 gtacattacc agatacataa taggcaagtt ctttttctgt ggctgttggg tacagcttaa
    35041 agaatgtttc cagaaatgcg gtagcgtcgt ttacagtatc agcgtctaca cttgcgtctg
    35101 cttctggtgt cttaggctca tagtctgatt tttcgattgc tggtgcaagg gtagggttct
    35161 gaacgattac catatccccg tcagcgtcta tatggacttt tacggtatag gttgctttca
    35221 cattgcttgt cttttctccc tcttttatct gctgatctac ttcgtaggta gcagaaaaag
    35281 tgttcgttcc cgattgttcg atactccata caatcacatt tgtagctgtg gagctggtcg
    35341 gtatatccgt tctgattgta tcaacattca agtcctgcaa ttcctttgtc agataaccgc
    35401 tgattgcctg cgtccttgct tcgatagctt ctttgctgtt attccatgtg tagtaggact
    35461 tcgcaaaatt cttcacgaaa ttttctatcc cgttggtgtc ctgcaagcaa agttcaatga
    35521 tttctttttc atgggtcgtg tgctggtcga tagcagtaaa attcttatac actccaaagc
    35581 tcacgcttgc gataagcacc acccacaacg caatcacggt tttcttatgt gtgcctacct
    35641 taacagtacg cacctttttt tcttttggtt ctttgatagt ttctgtctgt ttcttattct
    35701 tcttaaacat atttttcaag tcctttctat tgttttactc gtcctgcacc gattaagtgc
    35761 tgttgccagt aactattact taggtctgca tatcctatcg ggtcgcccgc atggtacatc
    35821 tggttatttc ctacataaat gccgacgtgg gttacatacg aaccagcgtt ataggtggaa
    35881 tggaaaaata ccaagtcccc agcctttgcc tgcgaaagcg gaagatgttg ggtagcgtca
    35941 tattgtgctt gtgctgttct cggtaaggag ataccagctt ttccataaca ccattgcatc
    36001 agtcccgagc agtcaaagga agtgttggga ttgctaccgc catacacata cttccagcct
    36061 tgatatttca acgcttcatt cattaccttt tgtgccagct ctcccgatac ctgcggaaca
    36121 gttaaatact gattgactaa ttccacatag aacatatttc catagccata ccgccagccc
    36181 ccgttctttg caacggctat cgggttggtg taggttactt tctttccacc cgatttctca
    36241 cgggcgaagc tctctgcaag attaaaggta tatttctttc cttttcctgc cacatatccc
    36301 acataaccac cgccataatt ataggactgt atcgctacat tcaagtcgtc gataccttga
    36361 ttttggcagg aagaaagcag ggacgcaaaa tatttacacc cctgcttgat tgaactttcg
    36421 gtatctaaag agttgggtgg tagtcccaaa ctttccgaac tctgcataac atcttctgcc
    36481 gtaccgccac tttctacttg aataatagca agtagcacat tgacatactc ggagataccg
    36541 ttttctctgg cgtatttttc caccataggc tgatgtttca aaacttctgc ggataaattc
    36601 ataaccgtaa tgccagaaga aaagttgctg ttttcgtcgt cgctgtccgc actaatgagg
    36661 acaccaaaga acagcaccag agaaaagagg ataggaaaca gactgccaat aagagcgata
    36721 tgtttcagtt tcattttttc ttctgtcctt tcttcattac aaggttacgg ttcttttcgg
    36781 tatgttccgt tgtacgcttt gattgttcaa aggtctgtgc ctttgtggta cgctctgctt
    36841 tgtaattctg gtgtgtttcc tgcgatacca ctttttctac attctgccta tgtgctggct
    36901 gtataggctg ggacgctttt ctatcagaag caccagaaga taacggacgc tctttgataa
    36961 cacttgtctt gactggctca cttatctttg aagtggtcgc tgtggcaggg cgtttgactt
    37021 cctgcatttt ttccacactc ggctttggaa tggtcgaagc tgtggctggt cgctcatggg
    37081 gacgggtagc tcccgttgtc gctgatccgt cagcctttcg ctgtgcctgc cttgcttctt
    37141 gtgctttttg aagctccata cgcttgtcag cgatattctg cctgcgttgc tcctgctttt
    37201 ccaatcgtcc cgtctgtctg gactgctgtt cctgcaccat gccacgcttg aaatctgata
    37261 cgctggactt tgccttttcc tttgcggaat ataccgcata agcggtctgt gtcggcatat
    37321 ccttgatgtt ttctttgaca gcgtttgcct tgtctttcac tttatttttc gtatctaaga
    37381 cagcacccac ctttgagcct gctcgctgtc ccatgctgga agtggtattg ccccgatttt
    37441 ctttagaagc tgtatttttt ctttccgctc gtttgccagc aacggcactt ccagccaccg
    37501 caccagccac accacccgaa ataccgccag cacttactgc ccttgcaata cggtgttcca
    37561 tacgcctagc tctatgtcgc ataaacagat acggtctgcg gaatatcctg cgtcccatat
    37621 tttgactgtc gccagcgttc aaagagaaca tattcattaa gtcgcctaac ttgataaaga
    37681 tacctgcgaa acacactatc tgtaagaacg ccaccataaa aaacgggtaa tctttggaga
    37741 tgttataaaa catactggaa atactgaacg ccaccgttac aatgagcgtt attcctgccc
    37801 gtgtcattat ggtattaaac accctcacga ttgcctgctt tgccagattt tcttgactag
    37861 gtatcatgga aagaagaaaa ctgataggca aaaacattgc aaagataata aaaagtatct
    37921 ggcttaacat cattatcccc atcagtaaga atacaaagat tgtgatacct atattaaaaa
    37981 tgaataggaa gaacaccata cccaagcggt ttaccacctg cggtatcgtc agattgttgt
    38041 tgtcgttatc ctcgatttct gttttcacga cttcctctct ggtctttccg tcctcgtcct
    38101 ctgggcttgc cgatacaaga gcttctacac ggtctgcccc gatttcttct gcgttgctgt
    38161 tcccgaattg taagagtaac cacggctgtt ccacttgaat agaaaataga ctgtcccgta
    38221 tcaagtctac gctgtccttg ccctcgctgt cagagtttgg gagcatgatt tttgttccca
    38281 agtcaagtga agcggtactg atgtctgatg aaaactcatt tatcttcttg atgtagtcgg
    38341 gagcataggc aataaacgaa gcggacagca cgaacaccac cacaaagttg ataacggcat
    38401 gaagtgcttt actggtttcc cgtttgataa gtcccgtata tgcaacataa agtcccacca
    38461 ctaagataat gagaagcagg aaaccaacat agaagccaga gctggaaaaa ccgtttgccg
    38521 taacacctgc aagggtctgt atgctttttc cgatactgtc tgccatatcg ttaataaaat
    38581 caagtttgta ggcttcctgc accacatagc ccgtagcatt gcttaaatat aggcttatcg
    38641 tccagacaaa gttggtaatg cagtaaagcc cgtactgcac cgattttccg ataccgtcca
    38701 gccagttcca cggaagccac gaccagctat tatccacata aaaatcaagc tggtagttgg
    38761 aaaggggata ttttgagtaa agattttctg cgtttatggt atcgtccaca agccccgtcg
    38821 catgagccac cgtccccaaa agtgaaagca ggataaggga gagtgccacc acgaacagag
    38881 ccattttaag aaagtggaaa atcttctttt ttgtgaacgc accttttatc ctttctttca
    38941 tcactccacc tcatttctct gtacgggcgg tcttgtatca aaggcgtgta gcagttcttc
    39001 aaaaacgggg tgtatctgca ccacaccgac acgcccgtat aaatcctgta ataaacattg
    39061 tccgttctcc aaatcacgca agcgtttctg gttattttcg tcgtccttgt caatgccgaa
    39121 aaattctaag gtctgcttta tctcgttgat gtcagtagaa cgaaaggcaa acttcaagcc
    39181 gatattgttt ttcagacttt cctttgccac gtccccagaa gattgtgtaa cgaaataaac
    39241 gcctgcctgc atagctcgtc cagcacgaac cagcttgttt gataaggttt cgccttgtgc
    39301 cacatttaag aacgcccacg cttcgtcaag gtctacaatc ttaaaaatac ttctgtcaga
    39361 atggataaaa tcaagggcaa aggtactaat cacaatcagc atagacaccg acaataattc
    39421 aatggtcgtg tattcctcaa aagttgtgtc cttatctggc aacacaaggt cagctacttg
    39481 aatgatattg agctgattat ccagactgat agcattttcc accgtaccgt ctgaaaacag
    39541 caggtgtgca aagtcgtagt ccgtgaagct gtcgatatgg tctgcgatat ttcttgatac
    39601 tggcgtatct tcacggcgta actcgtctat cacatggagc aagccccgac tgtcgctctg
    39661 ggtaacagaa cgtaccgctt ttcgtaacac gggaaatttt tcgccgtccc tagaggaaat
    39721 acccgtaagg aatgttaaga tgtcgattgc cagactttca gcgtccttaa cattcttcat
    39781 aatcacgaat gggtcaagaa gtcctgcatt gtccttgtcg cttgttaggt ttacgatatt
    39841 gatttcatgg gcgatttctg ggagcgtttc tttccagttg ccacgctcac ttttagggtc
    39901 taacagaagt gcttgaccgc caaacagcac cgaataatac accagaagat tgttacagaa
    39961 cgatttccca ccgccaagcg aaccgacaaa agcagacgct aaagcgttgg taactgtacc
    40021 ttttacacct tgactggcaa gggacggttg caggtacaca tttcttcccg tatcaacaga
    40081 atagcccata tagatacccg tagtttctcc taactgctgg gtagcaccaa aaccaagccc
    40141 tgctagaaaa tctgatttta catactgcac ataatcattg atatatcgct tgctggcagg
    40201 aagaaattct gaatgaagcc ccagcatatc cccagcagga cgcaccagtt ttacattgag
    40261 gtcgtcgtaa aagtccttga cttcatcaca acggcgtttc agctcgtcaa gatcgggtgc
    40321 agacacccgt atgacgtagc ttaacttata catactttct ttgctctggt ctaagtccgt
    40381 ttccagctcg tccacgctat ctaatgcgtc caccacattt gagctggttt cacttcctgc
    40441 ttgataagcg tgattgtcaa ggtctttcaa ttcctttttc ttgttgcgga ctgtcgttaa
    40501 tgctttccga ttttccacga tttctacatt catagaagta tcaacgggga atgtgaattg
    40561 ctgttgctgg aaatagaaga tttcactgga cggaaaatcc agctcgccca caatcgcatt
    40621 gacggtaaag taggacacat agctttcctt gtcctcatgt tccaatcgta aatacctttg
    40681 gctttcctca atcacacatc ttgtcggacg aataaggtcg tagtatttta tctgcgtttc
    40741 tctcctcaat ttcttctttg gtaactgata ctcataatct tcataagcga caccgtccct
    40801 accgtaaaga tgttctatga gatacccgaa gtcgtttgtt tccaagcgtc gcaccttgaa
    40861 acgacgggat attttgtttt ccagtaactt ttccattttc atgtagcggt tgatttcatc
    40921 atttggcatg gaaacaaagt cattcatcag cgtgtggttc acttcatgga gaaattccgt
    40981 gaacgtcagc cacgccgatt ttttgatgtt cttcagattg agctgttctt ccgtaaccat
    41041 gagcttaaag ccaagaaaaa agcggtagtc cacttgatta tccccaatca tagatactaa
    41101 cgcttcggtc tgttcgtcta tcttctgata ggcaacttcc tttaattttc cagttaccag
    41161 cttttttgac tgctcctgca tacttcggat tgagctttct gtggcaatct gcaacgcatg
    41221 aattttaccc tcacgggact gtgcaatgag ctgtcgaaag ctgtcatgca cgataaattt
    41281 ctgctctgcg gataagaaag aatagttgta cggtatcagc tcataatagg caaacacctc
    41341 attgtccttg ttccagacaa ggttattgtc aatatatttt atcgggaaca tagttcacac
    41401 tccttactgc cgtgattgtt tcattgagta tctgcttatg cagttttacg gcttttcctg
    41461 cataagtgat ttttggtcgc agggcatagg ttatctgtga tttcaaaaag ctgtacggct
    41521 tctttccgtc aaaagttttc tgcgacataa accaagtgag agcaacggga ataccgaagt
    41581 atttgagaaa tgctccctca atcatggaaa gtgggggaat atccccaaac agaatgatga
    41641 taaattctgt aatcacaaac catgtaatct gcgtaaaggt aacgggaaag ggcaagttaa
    41701 agtcattaat tgcatacaag actttttcca cgttccagat acccgtataa gatttaatct
    41761 ttttcaagtt ctttcagctc ctttcaaaat agaaaaggac agccatgttt cagactgtcc
    41821 cttaaaagag aaatacgctg tcagtagcaa caatgcttgt cgctgatctt ccagcgttaa
    41881 tatggtatct cgcacatacc tcggcttgtt tcaatgaagc aaccgcccat atccaaatct
    41941 cgcccgtagg cttcatagtc aatgtagttc tgtaagctgg gtggaatgtc gccaagtgcc
    42001 tgcaattcgt ctatgtagta gtaggcaacg tctgtcatgg tttcacagtc tggataataa
    42061 taaatatcgt ccttgtgttc cacgacttct tccagcgtcc cgtagtggct gataaattcg
    42121 tccagacact ctacgatata gtcgggaagt tcctctatca tttcatacat agagttcagt
    42181 tcttcaatgg aaacatactc gccaatcgca atgggaaagt tatcggtatc atggattgcg
    42241 tattcctcat actgttcatt caagccgatt ttttctttca catcttcctc gtcaatgggg
    42301 aacgtgaacc acgcaccgac taaatagccc tcgttgtatt tgccaagatt agcaatataa
    42361 accgccatat catcaatcat aagcaccacc tcatttccta ctctggcagt tcaaagatac
    42421 cgtgttccgt tactaaaaat ttcccgtgtt cctgcaagtg agaagcgtag gcttcaaagt
    42481 caaagtaata ttcttgacag tcctcggata aatgtttgaa cgtcgggtcg ttcatcagct
    42541 tttgccttgc aacatctatc atgcttttgc agtcgggata aaccgtaatc acgttcctgc
    42601 aaatataaag tgcttctaaa ttctcaaaca ccgtaagaag tgatacatat tcttcctgca
    42661 tatcgcttga aagctggcgg tacataaaat ctaattcgtt gagctgatac acgctggtat
    42721 gttcgtgaac ttcattagca aaagccaaca ccttttcaat aatgcggtaa tccccacttt
    42781 ctgcaccgac acctaacttt tcttcaaact cggcaacatc tatcggcagg tcgaaccagt
    42841 atgatattgt ttcttcgcca gttgttcctc tcgtttccac cagcaccctt gtttcctgca
    42901 ttgttcctca cgtcctttct gttgtttcat cacatctttt aaggtctggt acggcatacc
    42961 aaacacatac tttgaaaaat cttctaactg tctttcttca tagtcggcaa ggttcagccg
    43021 tttcatttcc tgccacacct tacgcttgta agagggctgg tcggaaatat attcacagcc
    43081 aacctttacc tgcatatcct taaaaatatc gctcatttca tcactccaat ctgaaattta
    43141 ggtaagaaaa aagcagtcaa tcctaagact aactgctttg tgtgtatgga tatgaaattg
    43201 taaactagat tatctgttat agatttacag tcataatata ttcttcgcta ttttcatcaa
    43261 caacaagaaa acctgctttc ttatacatct ttactgcata attatttttt tgaacagata
    43321 aggaaagttt tgaatatcca gaagtttttt ccaccaacaa taactgttgc aataatgaag
    43381 ttccaatccc ttgtcctcta tacttttgaa aaacagacat agcaagggac ggtgtatcat
    43441 tgtcaatgtg tccgtaatcg ttcattattc gtacccaaat agcaccaaca acatttcctt
    43501 gaacttccgc aactaaagcc ctatcatctt ttcgctttcc gaattcaaaa acatattctt
    43561 gcaattctgg gcagttaatg attgatttag gtggtggctc aacaccgtct ggaatataaa
    43621 ttgcattata caaaaagtca ttgagtaaat catattcttc cttttttatt tctcgtataa
    43681 tataatccat agcttaactc ctaatctatt ttatcttttt tcacaccccg attatatcat
    43741 tcgcatatca gtaccacaat aaaattttat gcaccaataa tcttattgaa cagctctaac
    43801 agtacatctt tcacaccgcc agcattgaat accaaaccga cagcaatcaa ggcaactacc
    43861 aagaagccaa taagttttga aaactcacgt ttaaacccta agtagatacc gataaccaca
    43921 atcgccataa gcactaagct ctgtgcgttt gataaaaacc attgatacaa attttgtccg
    43981 aaattcattt aattgtcctc gctttcttct aattgtttca tttcatagtc agcttctttg
    44041 ccgatattca aaatacacat caagactaca ccgataccca ttcccataga taccagcagg
    44101 aagtctttta ataataccca catttttatc actcctaact ttctactaaa tcttttgcag
    44161 gggtcgtctg ctgtttgatt atcatttcat gcttttctgt gagctttgcc tgctgttcga
    44221 ttgtttccat gtagtctgta ccgtttccct tatcaatctt tttcagcatt ttcaaggttg
    44281 gtgctacctg cctttgtacc caccgcaatg tacggtctaa ggtataaggc tctggctttg
    44341 tcgtcagctt caagctctgt ctgttatcgc cgataaacca cgcccagcgg tcattgagtt
    44401 tccagtcatt ttttcgcttg tctggttctt catcaacaaa ccgcacatac tggttgatga
    44461 tagaaaaggc ggtctgctct gcgtcataat aggtcagcaa atctcgtact gcataatagg
    44521 ctcgttcatt ccgaagccgt atctcaaaac ggttgataat gtcggcttct tccagaggtg
    44581 tccccagctt gacgtactgc tcatagtcct tttcatagat acagaaatac acatctgatt
    44641 tcagcgaacc aagataaagg gtacgtccca tatattctct gtcgtcctct ctgtgcttga
    44701 taagctcgcc cgactggtaa aacttatagc ttctggactt tccgatatat tcccgtttcc
    44761 tgcatttttc cgcaagctct ggaatatcca aaatgcccgt atggtcgttg atagcaaggt
    44821 cgatacgctt catcacgcca ccgtctacga gtgcgtccat gagaaagtca taccagcttc
    44881 tttgctgtgc cagcaggtaa ctttcaaact gcctgcaccc acgccccttt aactctaaaa
    44941 ggacaccttt ttcttcgtca gccgacgtat agataaagat gtcccctaaa gaataatgct
    45001 ccgtataact gtaacgcccg taatcttcat ggagcatata gttgatattc agttttaata
    45061 tgtctttgat gatgtgctgt atatccagcg tgggaaaacg gattttcaca taatcaaaca
    45121 gcatggtaag cggtgcttct ggattgaacc ttgccagttc tttatgcaga gtttccagaa
    45181 gttcttttga cggcttcatt tttccacttt ctatcttgtt gagatattcc cttgtgatac
    45241 cagaagccaa cgccagcctg ccttgtgaga taccataagc aatccgtttc tcccgtaatt
    45301 cttttatcca ttgttcttca ttcagaacca tacccccaat ctgtaaagtg tgaagttttt
    45361 taaggcgact tcacagccga tttttactag gaaaccatgt cagaagcctt atgtttccta
    45421 tgttttttgt ctattgttta tttgcaaacg tacccctctg ttagataccg aggggttcat
    45481 cagcagagca gggacaagcc ctgctctgca aaacggcttc cacggtcgta tttgctccgc
    45541 cgaccgttcc tgccgttgtg caggcagaac ttatcctacc tgttcatacc aatgtaaacc
    45601 atgatgaatg aaacatcagc ggataaacat aaatttaatg tttcttctga tatttcactt
    45661 ttacggatag ggtctgtttc cagaaaagac ttatcaagca attcaaaaac aaaatcaatc
    45721 tggctgttgc aagccgactg ttttctattt aagcgtatca agaacaaatc gggcatgaag
    45781 tttttttcgt gaattgcatt ttcaagaata gtatcagctt ttttctcaaa ctgatgtttt
    45841 ggattacatt taaaatcgtg ataacgtttc tgcacaaatc cctcgcaatc ggctagaaaa
    45901 tctccataat tgatacagat acattttacg ctcttagatt tctcgtcttt atcttctgat
    45961 tgtattattt tattgatttc ttttatttcc atgagttagt tctcctttcc ttgttgttct
    46021 ggcataactt gtctttcttg tgcaagcctg ccgatagtct gcaaaaaatc atgtcctttc
    46081 gggactaaag gcgtgtaaaa ttcacttatc acgcttgttc ccacatcaca ataaccacgc
    46141 cccttgatac gcttctggaa aaactgcttt ttcacgtctg aaccaaacag cataccgtaa
    46201 cctaattcac tgatacgccc aagtcccaca cggaaattga agttatctct gataccgtct
    46261 gaaaaatact ttgcgtctgg acgctggcag gcaacgataa ggaaatatcc tgcttgtcgt
    46321 cccaacataa cgattttctt taactggcta agcaggctca cgctttcttt cgtcccaagc
    46381 atttcaaaaa atgctacata ttcatcaaag ataagaaagc agggtggaag tcccagatag
    46441 gcgtagtttt cgccagtctt atagttcggg tgtcgcttca tttcctcact tcgctgtacc
    46501 atgccctcat aaaaggcatt gacgcaatct atcatttctt ctttggtgtg atacacattt
    46561 cccataactg tccctaagtc tgcaaggtca gcgttcttcg ggtctaagat ataaaggaca
    46621 gcgttggtat gcagtaaggc ttcaatgagc gtcagcagga aataggtttt accgccaccc
    46681 gttccaccag caatcagagc gtgagggagt gcgtcatatt cccagacaag attgttcatc
    46741 agtttcagac tgccgttttc tgcccgtact tcatcaatgg taatgcggtt cgctatcata
    46801 tcataaagca gggtatattc gatatagccg tcatgcaggg tcttgtcggt cagctcgcaa
    46861 tacaagccac tttccaattt atcctctaac cgtaaaagct ggtcttgata ttttcctaat
    46921 gtgatttcac agcggatatg aagcagtccc ttttccattt gataataaat ctttggaaac
    46981 cagacgattt tttcccttga tctgctttgc aggtcagtaa aaaaaccgct gtcttgtacg
    47041 gtatcggctt cataccactt attttccagt atcattcttg ccagcttttg acggtgcagg
    47101 agcttcttga aactgtcgta acagaagcgg taatacagaa aagcgaccaa tacacaagca
    47161 ccagtcgcta tcagtatggt tatgaagttg taaggggaga gcgtcaagtc gttttctaac
    47221 aagctgaaat gctcccaatc ggtacacatg agctgtttga tattcagtag cagaagaacc
    47281 gccacgaaca caaacagaag cgtccctatg gaaaagtggt agacaaggtg cttgtcgctg
    47341 gctctgatac gatgtccttt attccaaatc ttacgcataa atcattcgct cctttctggg
    47401 tatgaaaaaa gcagtcaatc gtatagacta actgctttgt aaatgttgca agatataatc
    47461 ataaatctgc atttttagtt atattaaggt cgcacatata atgccaatta caccaatagc
    47521 caaaaataac agtccaacac ctgctgattt tttacgtttt tctaattctt ttgagttgct
    47581 ttcactcata tttacaatag ggtattttct tcttccgatt agatacataa gcaaaccact
    47641 tgaattattc ccactcattg taaatactcc ccaaaattta gggtgcttta atcctctggc
    47701 tgttgcgtct ataacagtca tatgataaat ctgaaacaca acacaaaacg ctcctacaag
    47761 tgcaactgct ccacaaatta ccgctaaaac tatgttcaaa tccataacaa aatatcctcc
    47821 ttaaaacttt ttgattatct ggtaaagtaa tgctgatgaa gtgataacca taagacaaaa
    47881 tattccaact aagaaataac ggttatctgg tataaacata tttaatgtta tcagcaatgc
    47941 tacgacaatg atatttacaa taattgccca tatcattttt tggttgcttt ttacaacatt
    48001 tgtactttct tctaaatgtt caatcatttt ttcatcaccc tttagcaata cgtcaagact
    48061 tatagaatat aggttgctca actctattac actgataatg tctgggtaag atttttcatt
    48121 ttcccagttt gaaattgtct gccttgatac attgattttt tctgcaacat tttcttgtgt
    48181 cattccagac tgtactcgtg catttttaag tttcttacct atttccatat ttcgattgct
    48241 cctttcggtg tcattgtcat atattaaccc tcaaatgtct atccaatatc ttcgacaaag
    48301 ccttttttcc ttgtcaaaat tgttttacat agcttaaata cggctctttt ggctcattat
    48361 actgtaattt cagagtaaaa tctatgacct agatttattt ttttgactgt ccttgcggtg
    48421 tatggttctg tggactgcct gcgttctggt tgcctttatt cttcaacaca atatcctctg
    48481 cctttacata ccagtccaca tctgcacccg tataagtttt tcgtgatact gtatcggcta
    48541 ctggattgac aagctccacg actgcattgt acggaaattc ccttaacggt acttctggcg
    48601 gtacagacac ggggataatt ccaccatgca gactgcactt caaatcatag atacgctttt
    48661 taagctgggt actcggtgtc ccgtcctcat tctgtaagaa cacatcacgc accgctgtaa
    48721 attttaattc tccaaatgtt ttttctttgt caataacaaa cccgtttgat aatctcataa
    48781 attcttcact cctttacttt tcttcaactg ctacaatatc atcagcaact aatacataat
    48841 cggtatgtcc catatccccg attgcgtaac ctctgccgta taacttcgga ttgacaagtt
    48901 ttactttctg ctcatacttg aacttctttt cgccagcctg cacgggaatt tccaccacaa
    48961 cattttcgcc tttctgtacg tcagaataaa ggttatagct tcgtctggct aagaccctac
    49021 ggttattttt atctctttca aagataggct cgctttcgcc tgcaaattca agagttccaa
    49081 aagactgtgc catatctggc acgacatatt tcatttccat attgttttac ctcgtttctt
    49141 tctattttta ataaattgat tgtgatttct tattctggcg gtttgggaag taccagcaat
    49201 cccacagata gtaaagggta aaatcaatgc ttacgcaccc ttgactatcc gtgttcttgc
    49261 aggttgttgg cagacaagcc agaataagcg gaagtctgcc gtttgacagc ttcggcggag
    49321 agcgtgattt ttcttttctc ataccgttac cgccttatga ttttttcatt ttacggcgtt
    49381 tgtagaagaa gatacctgcc agtccagcac cagaggtcaa aagaagtgca agcagtccgt
    49441 aaaggtttgt gttatcgccc gttttgggac tgtcgctcgg tctgttaggc ttttctggtg
    49501 tcggtggtgt ttcgggtttc tctggttctt ctggcttttc cttaaaggta attgtctgtc
    49561 ccttatcctc aatatcctta tgttcggtaa ctttcttcgg ttcgtctgga ttgctcaaat
    49621 cgtacaattc ttcaaaagtt acaagctgtt tgccgtcaag agaagtagcg tcaaaggtaa
    49681 aggcaacttc cactttcata gtttcgctgt cagcgataaa cgtataatca ctttccacac
    49741 gttttccatt gataagaagc tctgcatttt cttcccttaa catctgccag cccacaagtt
    49801 tgtactgtgt accgacttcc aagccctcta aggttacggt atcaatgaat gtaacgtctt
    49861 ttccagcttc aagctctttg ttgccgtcct tatccgtagc agtcgtatgt atcttgatga
    49921 tacgttctgt aattaaaacg gtctgcccgt cgtcctcaat gtctttatgt tccgcaactt
    49981 tcacgggttc gtctggattg ctgaaatcat acaattcttc aaaggtaaca aggtttttgc
    50041 cacctaaagc agacgcattg aatgtatagg aaatttccac tttcatttct tcatcatcag
    50101 cgacaaaagt ataatcgttt tctacacgtt tcccgtcaat gataagctct gtattttctt
    50161 cttttaacat ctgccagcct ttgagctgat actttgtgcc ttttgtaagt ccgtctaatt
    50221 tgacagtatc aacgattgtt acctcttttc ctgcaaggat agttttttcg ccgtctttgc
    50281 tggttgctgt ggtatggata gagatttctt tttcgtattc atcagtcagc gttcctaaat
    50341 caaccacaag gttatttctt gataccacga tttcaaaagg tgggataagt tcaaaacctt
    50401 tgttactgtc gcaacgcatt tcttcaatga tgtaggtatc ataaggcaac gcacccttgc
    50461 tgtcgtctgg ttcagaagtt ccaaaccaca caccgtcctc gctggtcttt cctgcgtttg
    50521 tattgtgctt atgtgaagcc cagtcagcag aagtggaaaa ctgcccgtta tcatcagtta
    50581 ccacaacatg attttcgccc gtcgtcttgc ttgtgatcct aaagggaaca tcagcaagac
    50641 gcttgtgtgt gcctgcaccg atttttacac cctcaatatc tccacgctta atctgattat
    50701 agatagaatg ggcttcgtct gttaagtcca cgatttttcc attttctgtg attgtaaaat
    50761 caatcggttt tgcaccgtca gttaagtaac cgttgggagc ttcactttca acgatacgga
    50821 attttccata aggtaaaagg tcagcagaag tagaagtgat accctcaata tctgtacgaa
    50881 ttgtctttac cacttcattt ttcttataga gcttaccctc aaccaatacc gcattttcat
    50941 ttaaggaaat gatgtcaaaa gctgtatctt tcaaagtggc acttccttgt ggctttgtat
    51001 cgcccgtttc taaatctcgt ttctgaattt tgacaccgcc acggataacc ttgtctgata
    51061 cggaaaactg gttacttcca gataatacgg caaggtcgcc gtcctcggta atctgtgtta
    51121 catataagcc cttaatctgt tcggacttat cgccagcctg catatatgca ccgtctaaca
    51181 agtagccgtt tggagctttt gtttcttcaa cggttagcgt tccaagtgga agaaccgcct
    51241 tgccgtcctg catatagaag ctgtcgccag ataccttgta agcgtccgct aattttgtaa
    51301 tataatgggt tgtcccgtcg ccgtctgttt cagcgattgt ctttgtaacc catgtacgag
    51361 tagcttcggc agggagattg tctttgttat agaagcctgc ataatacttc catgtaaatt
    51421 ccgcacctgc tagagaagcg ttcccctgcg gattgtcttt ctgtgtttcc atatcaatct
    51481 tgaaaagttc aatcaaagtg tccgttactt tcggcgtatc agatacattc aaggttgctg
    51541 tcgttccagc ttcaaccttt aaggaatata cagttttatc tactttatat cctgctggtg
    51601 cggataattc cttgatatag actgtgcctg cttttacctc tgcaacatct gtgtttccgt
    51661 tttcatcagt cgtaagggtg gcaagctgtt tcgtgcagtc cttatcagca aagacaccgt
    51721 atgttgcacc agcgattgag taattcccgt taccgtctgt aatgctggta ttactggaag
    51781 ccttttgaag tttcgcattt ccgacattca gtttcgccca gaattgtccc aattcctgcc
    51841 cctcgccaga gtagatataa ccgccacatt catagcgtcc tttattttct ttgacaaagg
    51901 ctctagcacc agagaaaact tcgtcctgcg ttgcctttgg aatttcatca taagaagctc
    51961 gcacgttatc acattgccag ccaagatgta cgctcaatct ctgccagact acaagctgtc
    52021 ttaaaaggta agcgtgattt ttgcttattc cgctgtggct gtctgtgtac tgtttcacat
    52081 attcgataga taaggcaacg tcgcttatct ggtcggcact catacgggtg cttgcgtcag
    52141 ctctggtctt gtagccgttc ctaaaatctg tgttaatgtc gatacagtaa gcgtcctcgc
    52201 cctcaacggt taaatgtccc tcattaaagg tagaaccaat cgaaccgtca ttcattactt
    52261 tttcaacgat accgacacgc tcttttgact ccgtccagta ttgcttgctt tctgcatgaa
    52321 cgggtgtcgt cggtaaagca gtaacgacag ttgcaagagc taagaagccc gtacacaatc
    52381 gttttaacat ctttttcata aatctaatgc tcctttcatt ttgggtaata aaatagccgt
    52441 ccaataagaa cggctggaaa tagaaaagga acgtcatgtt aggcgttcca tagtctatag
    52501 gttattcaat tttttcttgt ttcaatactg atgtgttgta ccatatcttt gcatatctag
    52561 gaaaacttgc gtatcaaggc tcattcgtta gtagtaaata agtagtaaat tgatgtgttt
    52621 gtttccttga aaatgctgat agatactgta ttttagcgga taatcagatt tttattgtgt
    52681 ttttagtaaa caaaattaaa aagttgagaa aaaattgagt tttaaaactt acactcttct
    52741 tatatagaaa aggagagtgt tttttatgat tataaaagca aaacaattat caaaaatata
    52801 tggttctaat aacaataaag ttatcgcact taataatgta aatttagaaa taaactcagg
    52861 tgaatttgtt tctataattg gaccttctgg aagtggaaaa agcacacttt tacatatttt
    52921 aagtggatta gataatccta cctctggaca agtgttactt gatgataaag atatatataa
    52981 acacagtgaa aaagaactat ctgcacttag aagaaaatcc tttggattcg tttttcaaca
    53041 gtttaatctt ttacctgttc ttacagcatc tgaaaatatt tcaatgcctg tacttctaga
    53101 taaaaaacaa cctgataaag actatttaaa tgaaatttca tcattacttg gaattgcaga
    53161 tagactcaat catcttcccc atgaactttc aggtggtcag caacaaagag ttgcaattgc
    53221 tagagcactt attgcaaaac cagatataat atttgctgat gagcctacag gaaacttgga
    53281 tagtaaaagt ggcagtgaag ttatgaatct tcttataaaa acttcaaaac agtttggaaa
    53341 gactttagtg gtaattactc atgatgatag aattgcaaaa cttgctgata gaaaaatttc
    53401 aattattgat ggtgttctta tggaggtgaa atagaaatga agaattacct ttcactttca
    53461 ataaaagaat taaaaagcca gaaacttatg actacattca tcattatagc aatagtacta
    53521 tcaactatta tgacaactgt ggttggacag tcaattggta tcctacaaaa tttaagaatt
    53581 gaacaagccc gttcttttaa tggtgataga catgtatcct ttcaccaact cactaaaaat
    53641 caagttgatg acataaagaa agatgataga gtttatcaag ctggtacttc aataactctt
    53701 ggcagtagta aaataaagga ttctggtatc tctgtacttg taaaagagta tgataaaaca
    53761 ggactttcta actaccccaa attaatgaaa ttaaaatctg gacatttgcc taaagataaa
    53821 aacgaaatag ccttagatga aaacacacta aagcttatag gtataaaacc aagactagga
    53881 gtgactatac ctatgaattt agatatttca cttttaaatg atacaatacc accatataat
    53941 tacacagcta actttaaatt gagtggtatt ttggaggatg attatacagg atacgtaagt
    54001 ggtatagtaa acggtattgt gggcaaaggt gcatcagaaa atctattacc taagagatat
    54061 attttatcct ctttggattt taaaataaaa cagcaagaga agtttcaaga aatagtaaat
    54121 caattagcta aaaaaataaa tctttctcac aattcaattc aatataattg gatttactta
    54181 aatgctctca aaatacagtt tgaaaaagat gaaaatagtt ctaatagtga tggtatatct
    54241 atgattatat tggtatcttt atttgttgcc ttattggttt tactggcttc tggacttgta
    54301 atctacaata ttttaaaaat ctctgttaca aagaaaatta aagagtatgg atgtttaaga
    54361 ggaataggag ctgaaccaaa ccagatatat aagatagtta ttttacaaat cttaatttta
    54421 tgtactattg ccatacctat tggagctgta attggaatta tatcttctaa aggcataact
    54481 ggaatggtca ctaatatctt aaatccagat atacttctag caaatgataa taaagaaatt
    54541 actgagctta tacataaaaa cacaacagca tatatgttcc cattagtatt aagcactagt
    54601 atatctttga ttttttcatt tatttcagca ttaccatcag caatatatgc ttcacatgtc
    54661 tctcccaaaa ttgctatggc tggcagtact accaaaatca aaagaaaaat taaacgagaa
    54721 aaaacaataa aaaactttga aagacatcta gcatggctaa acttaaaaag aaataaagga
    54781 agaactataa taaccatact atcattattt atgagtataa cagtattcgt tgcactgagt
    54841 gagttctcta atgtattaga tgtatctagg tcagtaagta atttaaaaga aggagatttt
    54901 tccttaacaa atgaaatatc tggttttgat aagtcaatac tagataaaat agataacatg
    54961 aaaaacgtca atcgcacttc ttttataaag tactctgaat acaaacaggg cgaaatagat
    55021 acagatataa attttgaaaa tagtggtgag atgttaaaaa tcattggaat tgatgaacaa
    55081 actttaaaag acttaatgcc ttctattaca gattctacat tagaagactt taaaaatggt
    55141 tctatctgtt ttataaaaaa tccacttgct atttctacac caggtgtaaa aactaaatat
    55201 acaaatttaa aacctaaaga taatatcaca attaacaaaa aacaactaga tatatatagt
    55261 acggtagata aaatgttctt tttacaaggt aatggctggg taaatggtgt tgatattatt
    55321 gtatatgatt ctgtttataa caccttgaca aataaaaaca agttcaacca gataaatatt
    55381 tatgctaaag ataaatcaga tttagaacaa ataagattgt ctattgaaca gatttgtgaa
    55441 aataatcctg gctctcattg gatatcatat attgaatcag ataagcaact taaagagagt
    55501 tttaaacaaa tagaacttct agcatgggca gttatattat ttgtgggatt gattggtact
    55561 ttaaacatca ttaacacaac tcatacaaat ataaatacta ggactaatga gattggagtt
    55621 aaaagagcta ttggtatgag taatagtagc ttatataaga tgtttttatg ggaaggtgtt
    55681 tattatggaa tttttgctgc tatacttggt tcaattgctg ggtatgctag tgctattatt
    55741 ataaacatgg caactataga aaagcttgat tttactaata taccaattac ttcaatttta
    55801 caagctacta ttatttctat acttgcatgt attatagcta ctcttattcc attaagaaaa
    55861 gttaaaaaaa tgaatataat tgactgtata gatatcaatt tataactatt ttacagataa
    55921 taatataaat cagattatca atgactgtct ccattttctt tcaaatctaa ctaataaacc
    55981 tttccaacta taatataagt tttaaaaaaa ggcctgtctc aaaatagaga taaacctttt
    56041 ttcattgttg gaatgatgaa aatatattta acttcacaaa aaaagagtgc ctcacgaact
    56101 aaaaatttcg ttctgagaca ctccccttta atttaaaata tatagttaaa tgctatgcca
    56161 aaatttcaca catgctccac ctgattttga attttctatt ttaacagacc ctccaagctg
    56221 ttccactaat tgtttgacaa tgtaaagccc aagaccagaa tgcccacctt tagtctgtct
    56281 agcttcatct cctcgataaa atttatcaag agcctttttt aaatctttag agctaaaccc
    56341 actgccagaa tcacaaatct cataagaaat acaatttttt tcagcctttg caataatact
    56401 aatattacca cctgacggag tgtattgcag actgttagat atgatattat caaaaattcg
    56461 tgtcaatcta tctaagtcta tttgaattgg tgattgtata ttaccataca ttttcaatat
    56521 aagttcaacg tccttttgat gagcctgtaa ttcatagtct tgtacctttt gcaccaaaaa
    56581 ttcaggtaaa tttataggaa caggatttaa ttgtatattt gacttttcta aatcagacgt
    56641 atattgcatc ttttggacaa gagcagcact tttttccgta ttttctctta tcactgtaag
    56701 atacctatga agtttttcat tgtcatctgt attattacca ataagtgcat ccgtatatcc
    56761 caaaacaata gaaagaggag attttaaatc atgtgctaga gcttccacca tttcaacacg
    56821 ttcctgctcc atcttccact gtgcagataa agagtttttt aattcgtctt tcatttcaga
    56881 aaaggcacta caaagtttac cgagttcatt atctgaataa tagtcgattt caaaatcaag
    56941 gtctttttct tttatcttct tggatgcatc aatcaataga tgtaatggtt gattgatatt
    57001 ctttacaaac tgcttagaaa gccatatagt aaaacctata acatatagaa atggagaaaa
    57061 catagctatt acaataactg caaacgtcaa cctccccata ctatttgcaa aggtcatttt
    57121 cacttggtag aatagaataa cagctccctc aatttttcca ttagtacctt taattggaac
    57181 agtataaata taaccacctt tacgaacagt tgtatttata aaattattaa ataattcttc
    57241 ttttgtttta aatggttttt tagggttatt accatataga atattgccat tatcatccac
    57301 aacttgatat aacataccat ccccgcgaat agttcttttt aaaccttctt catttgattg
    57361 tgataacaaa gctatgtttt tttcatcaat gtatttttta attctaggaa cttgtcgctc
    57421 ataatagttt ggtggataaa tatccttatt caaggaataa ataaacaaat aaaaagcaaa
    57481 tacataagta atcactgtgg caactatact agctattata ataaaaataa aagtacgcct
    57541 gaattgggtg gcaagtgatt gatttttcat ttaatgacct ctctcccttt acattttatt
    57601 ccacttatac ccaatccccc aaactgtgga aatgtattct ttttctggtg tcacagcaga
    57661 aaacttagct cgtatttttt tgactcgttc aacaacagtt gatgaatcac cttcagaatc
    57721 acacccccat actttttcat agatttgttc tcttgagaaa acttgtcctg catggagtgc
    57781 tagtaattca acaatatcat actctatttt tgttaaatca atatccttac catcaatttt
    57841 aattgcacgt tccttcatat ataagcataa cttttcaaaa tacaaagtag acctcttgtt
    57901 ctcctcattg atatactgtg aacgcttttc cctacgcaga ttagcttcaa tccttgccat
    57961 aagttcacgc aatccaaatg gctttgttac ataatcatcc cctccaaagg tcaacccttt
    58021 gattttgtcg gtttctgatt gttttgcact taagaatata attgggcaca aaacatcatc
    58081 tctaattgcc tggcatacct caaacccatc cattttaggc atcataatat ccagtataat
    58141 gaggtcaggc tcattttttg atagttctat acctgcctga ccatcataag ctattagcac
    58201 ttcatgccct tttgccttca attcgtcctc aagtagcatt actaaatcta tttcatcatc
    58261 aataatcaat attttactca atataacacc acctttctct tatgggaagg ttagtattaa
    58321 aacaatattc gtctattcgt aacttttcct tccctcccat attttaaacc aaataacgcc
    58381 tcctatcaag aatataatca aacctattgc tactactata aatactacag tagctgattg
    58441 catcatttta gagtaaaata cctcagttga aatagttcca gcttctttaa taaaataagt
    58501 acctggaagc atacctagtt ttactggcca tgtccaggga acaaatgccc agacttttgc
    58561 accaacgcta gttaatccaa gtattgctgc catcaaaatt ccaccaatac taataccaat
    58621 agacgcaccc ataccccatg caaaactcac ccaaagatga atagctaata gtggaagagt
    58681 cccaatcacc acaagtcctg ctgctgacag gaataaccat attgttgctc cagatggcac
    58741 tgcaatattc attcctatgc agagtatcaa cgtagcaata aatgtgcata tagttaggca
    58801 aaacagaaga aaaagaaatt ttcccagata taatctaaca cgagaaatac ctacacataa
    58861 aaaaccatta aaatttccag caagctcttc ctcctgcact ataaatcctg ctaaaatacc
    58921 tactccaata ggaatgatga atacagtcca tattgtaaaa aatccttcaa aagcaaattc
    58981 ttgtgtactt ccagatttaa ttgtgagata agcaaccaca cataatgaaa aaataatagg
    59041 catataaaga gtaagacctt ggactgccgt cctctttgct ctaagccatt ctgatgataa
    59101 tagttttatc atttgtcatc cctcctattg aaccaagctg cagtaagtgc tgttaatact
    59161 ataaacacaa ccaaagaaac aacaatccca ataggaatca ctgaagtatt caaaagtggg
    59221 tctccagctt ctaatatagt accattagga tgtatgttga tgattgggca taccattcta
    59281 actgcccaac tccaaggtac tgcaacccaa aatggttttg acgcagcaag gacaccaaat
    59341 atcatgccta aagctccaac tcccatactt aggaacatac ctttccatgt agctagccat
    59401 agctggattg gaagtatagc aagagaacca acccaacata caatacttgc ccctataatc
    59461 tgtccaaaag gaattggtcc agctttcaat attaaaccag tcataattgt tacgactatt
    59521 aaaactagcg ttgaaataaa actgtaaact gccatagcta taattttatt aatccaaatt
    59581 gtcatgggag acacattgtg tgtacgtaaa gcacgataat ttccagcttt tttttcctgg
    59641 gaagctacca aagtagcaaa caatgcaaat ccaatagaca gaaacatcat tgaccaccag
    59701 ttaaaaatca atgctaaaag actttcccat gcccaagaat ttatttgaga tagtggattt
    59761 tgcataagtg ttgattgcat tataaatgca tatgctgcaa aagatactgg gaaaaaaaca
    59821 ataagtttac ccataaaggt tcttttatac tttagaagtt ctgattgtaa agcattcatc
    59881 tgttttgtcc tcctttaaga ataacatctg taaaaaattc ttctagattt tcattagggt
    59941 caggcattcc ttgaaatagt agtcttcctc catttataat tcctatatta tctacaactt
    60001 gagcaacctc tgatagaata tggctagaaa gaattacagt tatacctttt tctggaaaag
    60061 aagcaatcaa ttcacgcaat tcttgaatgc caaaggggtc aagaccatta gttggctcat
    60121 ctagtattaa caactctggg tcattcaaaa gtgcaatagc aattcctaac ctttgtttca
    60181 tacccataga aaattgtgaa gctctctttt tacctgtatt tttcaaattt actatttcca
    60241 acacctcata aattttatct ttaggtattc ccaatatttt tgtatgtact aacaaatttt
    60301 cctctgctgt aaggtttcca tacaatgcag gagattctat taaagaacct attttttcaa
    60361 gagattctcg tttccaaggc tttctatcaa aaataatacg tccatctgtt gggcgaagaa
    60421 gaccaacaag cattttaagt gttgtggact ttcctgcacc atttggtcct aaaagtccat
    60481 atatactatt tcgttcaatt tgtagagaaa cattgttaac tgccatttgt tctccatatc
    60541 tttttgataa gttttttgtt tcaataatta aatctttcat atttatttct cccttcttgt
    60601 aatactttaa atctattact aagagaatac taacatgaaa aaataacaat tctataacac
    60661 ctaataattt taataaaaat taaaataaaa aatagagtta ccaattttat tttggcaact
    60721 ctatttaagt ttatgtttta cagttatatt agatttaagc ttagtttcat tatcacacta
    60781 acttcaaatt tactctataa tccttaaatc aagcactaat ttattaatca aacactaatc
    60841 tattaattta tatttcttta gacatctaat atagtctgct actaaacaat aattatttat
    60901 atcatattta tctaatcctt taaaagcagt tatttcatca ttatttttca tatacatatt
    60961 tccactgctc acttttttct tgtgatactt cttgagtaag tgtacttatt ttttcttgag
    61021 atattttttc aattaaactc tcctttcaat acttaaatat ccttctgaac ctccatgact
    61081 aaagtcacaa ggttcctaat tcatagaatt ttgcatacta aaatatgtct tactaattct
    61141 ccacaggata tcccccatag ttcctatggt tcttacataa gttatctatt ttaaattgtt
    61201 attagttaga ttctaaaaat tatttgtttt atcactaata taatactcat aaaaacttta
    61261 caaatcaatt taaatttgct accttttatt tataacaact tatagtacat ttctcctatg
    61321 cttttcaata tattactttt aaaaggaggt tttccttatg attttaaata gaactgagct
    61381 tttccgagga tattctttag atagatttaa cgagatatgc aatatattat cagtaaataa
    61441 aattaaatat aagtataaag tgaaaaataa tacttactct aaaaaacctt tttataatga
    61501 aataaccctt ggcaatttag gtcaaaaaga agatttctct tatgagtact taatttatgt
    61561 tcataaagac gattatgaac aggcagaagc tctaataaat tctaagttgc gatagattat
    61621 tgataaaaca tgacattctg ttgtcatgtt ttatatgtta ttatactttc aaatatgtta
    61681 ctatattttc aaaattatat accttaaaac tatactttta tagtaattta aagcttaaaa
    61741 ctaaggagac tcgttatatg aaaataaata taaaatcaac attaaatgaa tttattaaac
    61801 agaataatct ttttgatgac aacagaataa tatcctacct tcctaatata acaatagaca
    61861 cagacaaaat aaaaactata atgattaatg aagttgtccc aactaacacc aatgacgatt
    61921 tttatagtat agataaagat gctgattatt taaaaactac tattccttta tttaacaatg
    61981 caggaataga agtatctaat ataaatgata tcctagatat gggtatctat ataactaatg
    62041 ccgtaaaact tcctaaatca gaatatacaa taactcgtga tacaattaaa ttacatatgc
    62101 ctattttaga agaagaaatt aaattgttta aaaacctaga ggtagtaatg ttaatgggag
    62161 atgttgcaaa gaaatctttt aatatgatta ctaaaaaaca tataaaaaag aatgtcatcc
    62221 cttccatttc aacatataaa cttcgtaata atgaacttta ttatgataat ttaagagtat
    62281 ttccatcata tattatgact ggtggaaaca tactgattga aaaatcaaaa tttgaaatgg
    62341 catcagaaga tataaaaaaa atgttcgaga ttataaacgg ttgagattgc aaaataataa
    62401 aaactaattt agacaaataa taagtgcctc aaaaaattct atttataagg cacttttatt
    62461 ttatattagt gtaactatat gctattaata taactatata ctattaacat aattctaaaa
    62521 atatatcttt cacactcatt accccacttt ggctttttat caactatatt tttagctatc
    62581 aatataaacc ttttatttag tttaaagcta tacttgcaca gcttaaataa aaattttatt
    62641 taactatata cgtttattta atcaactata aatgaattat ttttaacaat tgacaaacta
    62701 aattaatgat aatatacttt atgtattaca aatgtaagta gaaggaggta tagtatgaaa
    62761 aagttaccac atatttcaga agcagaatat caagttatga aaattatttg gaaatatgct
    62821 cctatcagca ctactgaagt aattgaaaag ctggtagaaa caagtacatg gagtcctaaa
    62881 acaattcaaa caatgttatt gagattagtt aaaaaaggag ctttaacata tgaaaaaaat
    62941 agcagagtat tcgtttatac tccacttgtt aaagaagaag aatacgtagc tacagaaagt
    63001 agttcttttt taaatcgttt ttataatggc actcttaatt ctatggtact aaacttttta
    63061 gaaaatgata aactatctga agatgatatt gaggaactga gagaaatctt aaataaaagg
    63121 acgactaagg gggataaata aatatgtatg ccccattctt tatacgattt ttactcagta
    63181 cattaacctt atcaatatta attgttgtaa ttttacttgc caaaaaagta tttaaaaaac
    63241 atatttctgc aaagtaccaa tacaatattg gatttatatt gcttataatg ttaataattc
    63301 catttgtccc tcttaaatat attaatcttg gaaatgtatt taactattta tatactttta
    63361 atcaacttgg aagcaatact aataggactt ctatgataaa aaatagtcca aattctataa
    63421 ttaacaattc aaatgcatta aacgattttt cagtatccct aaaccaagtt aattttgata
    63481 ttttaaatat tttattgcta atattatgga taattggaat tttaatcatg atagttatta
    63541 ctattcattg caacattaaa ataaaaagta tgaaaaaatc aatacaaatt ttaagagatg
    63601 aggagatagt ttttatattt gaaaagtgta aaaaagatat tggtataaat aaggatttta
    63661 tactatgcaa atcacctatt ataaatacgc ctattacatt tggatacttt aaaccacaca
    63721 ttatattacc agataagtct atatctaaat tatctttaaa agatataaaa tatatcttac
    63781 ttcatgaatt gcaacatttt aaaaatagag atatgctgat aaattatata atgtgctttt
    63841 ttcaaatatt atattggttt aatcctcttg tatggtatgc atttaaagaa atgcgtatag
    63901 accgtgaaat tgcatgtgat atttcagttt taaaaaagct tgataaagat aatcatatag
    63961 aatatggaca aactctaata aactttgtag ataatatttc aagaccatca aatcttacac
    64021 ttacatcaga tattggtggg tcaaaaaaac aaataaaaaa acgactattg aagataatgg
    64081 attttcataa tgaatcaaat actttaaaat tcaaaagcat tttaattttt acattgatag
    64141 ctttaattgt atttggaaat attcctaaac tatctattat ggcagatatc aacgaaaaat
    64201 atagacctac aaataaacaa actatgtatg aggatttaag taagtatttt aaaggttttg
    64261 atggaagttt tgttatgtat gatttaaaat ccaagcaata tcatatttac aataaagaaa
    64321 aaagtaaaac aagaatttct ccaaattcta cctataagat ttatagtgca ttattgggat
    64381 tggaaaatgg gataataaca agagataatt cacatatacc ttgggatgga aaacatcatt
    64441 ctaatatttc ttggaatgaa gaccaagatt tattttctgc tatggaaaat tccgtaaact
    64501 ggtactttca gactctagat aaaaaaacag gcataaaaaa catacaaact tatcttgagc
    64561 aaattggata tggtaattat gatgtttcag gtggtatctc aaacttttgg ctagaatctt
    64621 cattaaaaat atcacctatt gaacaggtag aattacttga aagtttttat acaaataagt
    64681 ttaattttga agataaaaat atagaaactg taaaagattc attgttaata tcaaaaaaag
    64741 atggggtatc actttctggt aaaacaggta ctgctaatat aaatggaaaa gatgtgaatg
    64801 gttggtttat aggctatgta gaaaaaaatg aaaataccta tttctttgct acaaatattc
    64861 aaagcaaaga ttattctaat ggtatttcag catctaagat aacattatct atattaaatg
    64921 acaaaaaaat ctataatccc taatatattt actatacatt ctaaaaaatt cacataattt
    64981 tcatattaat tatctattaa attcatatac aaggcttatt atataaacat aaaagatagt
    65041 aaaactagct taaaaacata atataatacc ctatacaaat agtggcaact ctccctcaca
    65101 tcctcaattg ttgccactat ttaatttttt gtattaagta aaatatattt ttatcattta
    65161 aacaatgaaa aagaggcata tctctatttt gaaacagcct ctttaattgt tttagaattt
    65221 actaaaaagt ctaaaaacaa tttatctaaa atattattct caactgaata agattaattt
    65281 tcaaattgag taaatttaat cttcaaatac tgatttaaca ataggcataa catagtgact
    65341 tcccccacga ctctttacat cttcaatcat agcaattgct agatattgtt tatcattatt
    65401 tccatctaca gtaaaagcat taaaccaccc aagttcagta cctgtaacat catcttttga
    65461 tgctttaatt tctgctgtac cagttttccc agcaattcta attcctttaa tcatagcgct
    65521 atgacctgtg ccattaggac tttcaacaac ttgaagtagg tcatcacgaa taatttttac
    65581 agcttcttta gaaaacacac ctttcttcca aaattcagcc tgtaaattct ttttaaattc
    65641 aagatgaggt tttatcatgt ctccatcatt tacaaaggct gaatatattg atgccatatg
    65701 tactggattt acaagaagct taccctgtcc ataaccagta tctgctaatt gtatttcagt
    65761 ctcaaattta ttgtcagtac caaattttga agaggataac ccaaattcaa atggcatact
    65821 ttcatcaaat ccaagcttca acaactcttt tgacaataca tcttcaccta tttttaaggc
    65881 tgccttagca aaataaatat tatcagaata aatcaaagca ttttccatat ttacagtatt
    65941 tccataatct tttaacgtgg ttaccttata gcttccccaa ctagaatctt tttgccaact
    66001 tagaccgctg tgtccaaaat tttcatttgg attaatcttt cctgttgtta taccaatacc
    66061 agcagtaact ggtttaaaag aagacccagg acataatcgt gctttaaatc tattgtacat
    66121 tggtttattt tcatttttat tgagttcatt ccatctatct tctgacattc ccaatataaa
    66181 ctcatttgga ttgtacgacg gactacttac aagtgataaa acctctcctg ttttaggatt
    66241 cataactact gcacaacctt tatcattttt catttggtca tatagtttac tctgtagttt
    66301 tgaatccata gttagcttta catcttctcc atctaccttt ggctcagtta ctaaagtttc
    66361 tttcttgtca ccatatctat cagctatgat aatctcatat ccatcaatac cacgtattct
    66421 gtcttccagt aaactttcta aaccaatctt accaattata ctattagcat tgtacctctt
    66481 accttctttc tcctttagta tctctgcatt tacattttga acataaccag ttaagtgacc
    66541 agttttttca ccaaatggat atactctaac ctctgtatta gatattttaa ctccaggaat
    66601 actaagaagc gactcttgta gttccttatc ttcttctttt acagtaccat ccggattttc
    66661 ttttattttt tcaatagttt ttataggtac cattgaattt tcttttaccc aagatgcatt
    66721 taatttcttt tcaatttgtt caactgatac atttagtaag gtagataatt tttttaagtc
    66781 ttctatatta tcactcattt ttccagggac taatcctatc atagatgcaa gaccttgacc
    66841 agcaatcatc acaccatttc tatctaagat acgtcctctc ttacctttca gctttgacac
    66901 ccttacagtg ttatcttctt caagttctgg aaatatgacg cttgactgcc attttatttt
    66961 ataatttttc tgtctatctc tagttaatag tacttcattt gagaataaaa tttcacctgc
    67021 taaagtatcc atcttagaat catagtttat taatttatca ttgtttttat tttttttaat
    67081 atcattaatc ttaatactta tattgtgcgc atcaattcct tcatagattt ttttatttct
    67141 taaaacaaaa tcttcttttt tattttcaga cttgctcttt tcatctaata aatcatacat
    67201 tttctcatat tgttttttat tcgcaaaaga catatactgc ttaaacactt catctggttt
    67261 gtttttattg agtccatcta gtatgaattt tgctaaaaaa acaataataa ctataagtag
    67321 acacattaga aaaccaaaaa ttatcatttt tcttgctttt ttattttttc tcatataaac
    67381 cacctttatc atttaatata ttacatacgt aagctttaag gttaaagtaa tcttatagac
    67441 gtaactaatc tatgttttta ttatgttttt tagtatctca taaaaatatg taagcagtat
    67501 aattgatagt aatttatata ttacacatgt aagttttaaa agtcaataat aatattatta
    67561 tttaattatt ttttacatca acttaaaaat aaatcagttc cattatattc ttttgtattc
    67621 ttcaactatt ttataaatta accttattgt attgtaatta ttttatagta tataacttta
    67681 acttgacaaa acgacacaaa tgtctcataa ttaaaagtga cacttgtgtc gttaaaaagg
    67741 aggttaaaac atatgccaac aaaaggagaa caaactaaac aatttatcat tgatacatca
    67801 ataatgctat tttctgaaaa aggatatagt aatgtgacaa tgaaagatat atgtgaagca
    67861 tgtaatttaa gccgtggtgg tctatataga cactttaatt caccaaaaga aatttttatc
    67921 agtatattaa atactcataa acactactct caaaatttat tggataaagg tatcaaggaa
    67981 aatatatcag ctaagcatat gctagaatat tttttccaac aacaaaaggc tgacataaat
    68041 ggcaaatact gtggatttga ttttgcaata cacgaatttg cttttataga aaaagaccaa
    68101 cgtgattata tgaataaaag atacagttca gctatcacaa tgctttcaaa tttaatcgat
    68161 tatggacaat ctaaaagtga atttaaaaaa tgtgattcta aatcagttgc aatacacata
    68221 atgttcttat ttgatagcat gaaaacatct gcttccattt tgaaacttac aaataaagac
    68281 attgataatc aaataaagat tataaaggac atggtgattt tatatgaata aacaaaaatt
    68341 ctataaaatt gatttacaaa actgggaacg atatacacat ttttactact tttcaaaaat
    68401 gacaaatgta gggtttaatt tgactataga aatagatatt actaatttac ttaaggaaac
    68461 gaaaaaaaga aatattaaat tttatccagc gtatttatac acaataacta cttgcttaaa
    68521 tcgatataga gaactaaaaa tcgcatatga tgaagatgaa cttggatatt ggaacacgtt
    68581 aacgccactt tatgcgattt ttcatgatga taataagact ttctcctgaa cctccaatga
    68641 ctaaagtcac agagttcctg cttcatagaa ttttgcatac taaaatatgt cttactaatt
    68701 ctccacaggc tatccccata gttcctacgg ttcttacata agttat
//
LOCUS       DAMKOJ010000010        66945 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000010 DAMKOJ010000000
VERSION     DAMKOJ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66945
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.010"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            349..2904
                     /locus_tag="PC592_000758"
     CDS             349..2904
                     /locus_tag="PC592_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF4054767.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELDVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNISAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDGERIKIKD
                     RKFKKNILKYQPNRVNKQKKLNTVPKIRVKVKNLEQLEAVLNYDVDLIYYEDINTLSK
                     ALQMVSSISIDSSISTDLDTSSSSSISKELMGSNPNNIDTLNNKRSNTAVTDKKLIYS
                     APRIVRNKEYKQFEILDNIKGINNVQIGNWGCMEYFKDKDLYIDCYLNAFNSESINHF
                     KEEGASTVCLSQELNLNEIKQTLKYTDVETEAVIYGYAPMMVTEYCPMGVVVRDCKKD
                     KRVAKCKESNYALRDFTDASYRITQDVFCRSTIYNSKVTCMLDNLCELDEIGIDVFRI
                     DFTVEDSEMVKKVIEAHIEVLSNNYKLGEKATDLYKKLDEIGTVAGHYYKGVE"
     gene            3008..3586
                     /locus_tag="PC592_000759"
     CDS             3008..3586
                     /locus_tag="PC592_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF4054768.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRDLAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            3620..4096
                     /locus_tag="PC592_000760"
     CDS             3620..4096
                     /locus_tag="PC592_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HDF4054769.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYNNGKLKDYNVSFLD"
     gene            4630..5451
                     /locus_tag="PC592_000761"
     CDS             4630..5451
                     /locus_tag="PC592_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4054770.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVVEYNRESFELEPEKLLNFIKFRRSIRQYKDIEIEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIEGLYNLALNTDDNDPVRSMYKNT
                     FKKMYKRYKENGKDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVI"
     gene            5673..8189
                     /locus_tag="PC592_000762"
     CDS             5673..8189
                     /locus_tag="PC592_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF4054771.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSYIFSFSINAIANDNRTIRIA
                     YPIQKGLTEIDEQGNYYGYTYEYLLEIAQYTGWNYEFVQVPGDINESITKLMKMLENG
                     EIDIMGGTLYNESLQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQGVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNEEQLEALKNGKADVLLNVSMNPIEDVRTV
                     AKFSSRPFYFITPKGSTDLTQRLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKDTEKLKVGVLLNKPPFQNIDKNTGELKGISIDLLNHICDLTGLEFELVPIKS
                     QKDLEKMTKNHEIEIVAGIIYDYEYSRKHNIIMSRPFVSTQYAMMINNKLNENSLDGK
                     CLALTRGLNYEGQFKENIVWYDTLEECIEAVNKGDVDYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYEAQSICFGIIKKDKQELLNIFNKAITSISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDRESENNNNIANEIDKIRREYNKKFFDVIKSQ
                     ENGTTEMYSIVFDDTFHWIRITSKIIYNDRKIPMYVIGKISNIDYEKEEKNRLLDKVQ
                     RDSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLVGDKILID
                     VAKVLDESFTKDDIVGRLGGDEFSVYINDIINNEELINKCNDVYNRIHLIKLPNGKSL
                     SISMGVVIAKCGQEYDELYQIADNALYDSKREGRNRFKIV"
     gene            complement(8393..9844)
                     /locus_tag="PC592_000763"
     CDS             complement(8393..9844)
                     /locus_tag="PC592_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HDF4054772.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLITVNEEDGMNGADALDPSL
                     IKGQYILNLDSEEEGYLLVSCAGGKTCVVSLPVEYKKVEGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLDVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKDSKLEKICCETYERLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANIWDYVIEILKSMNQY"
     gene            10161..12539
                     /locus_tag="PC592_000764"
     CDS             10161..12539
                     /locus_tag="PC592_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF4054773.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKAEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTTDSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKSGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIERLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTHKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            12607..13020
                     /locus_tag="PC592_000765"
     CDS             12607..13020
                     /locus_tag="PC592_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF4054774.1"
                     /translation="MILVSACLIGINCKYSGDNNENEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGINVKSEKDL"
     gene            13346..15046
                     /locus_tag="PC592_000766"
     CDS             13346..15046
                     /locus_tag="PC592_000766"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDF4054775.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFAK
                     LENGDEEAKELWQWFRDESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKH
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLRLLGMHAPERM
                     "
     gene            15300..16223
                     /locus_tag="PC592_000767"
     CDS             15300..16223
                     /locus_tag="PC592_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054776.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLIIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVTYFKKE
                     KLLFEYLLSSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKFEDYDEESILLNILNVLYDVYMEDRTVEDEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKKIDPRSLIRLEEGNTIIDPIFNQ
                     ITVISKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(16228..16434)
                     /locus_tag="PC592_000768"
     CDS             complement(16228..16434)
                     /locus_tag="PC592_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054777.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            16570..18324
                     /locus_tag="PC592_000769"
     CDS             16570..18324
                     /locus_tag="PC592_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HDF4054778.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVDMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYDAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQNLDE
                     IPSPYENLNPREYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLERIKRDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREAENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            18342..19484
                     /locus_tag="PC592_000770"
     CDS             18342..19484
                     /locus_tag="PC592_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF4054779.1"
                     /translation="MDFKIEKYLLRKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     AYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEEVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEIQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(19658..20596)
                     /locus_tag="PC592_000771"
     CDS             complement(19658..20596)
                     /locus_tag="PC592_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4054780.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIIELEEELG
                     VKLLVRGNRKITLTNEGKLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGGGETEA
                     MRLIARTAHNFHQKYPNVKYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYTQI
                     PATDVWGLLMRKDSTLASQNTINPKDLCNIPLIISRQTLVDKAISKWLQDSTEKLNIV
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSILLDTSELDISKLNTPEVK"
     gene            20822..21400
                     /locus_tag="PC592_000772"
     CDS             20822..21400
                     /locus_tag="PC592_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF4054781.1"
                     /translation="MNINEFLTHVNQGKPVSSKSEIHKFMVKLSNEAMRITSELNSYY
                     HEPEEIHSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKDVAENTIVGGVPAKILRVIDKITE"
     gene            21515..22426
                     /locus_tag="PC592_000773"
     CDS             21515..22426
                     /locus_tag="PC592_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF4054782.1"
                     /translation="MIKKLDDILDQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKVKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGDNVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            23033..24952
                     /gene="cooS"
                     /locus_tag="PC592_000774"
     CDS             23033..24952
                     /gene="cooS"
                     /locus_tag="PC592_000774"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF4054783.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMEADAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            25261..26040
                     /locus_tag="PC592_000775"
     CDS             25261..26040
                     /locus_tag="PC592_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4054784.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            26289..27965
                     /locus_tag="PC592_000776"
     CDS             26289..27965
                     /locus_tag="PC592_000776"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDF4054785.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNEENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKALGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFKFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLERLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            28050..28682
                     /locus_tag="PC592_000777"
     CDS             28050..28682
                     /locus_tag="PC592_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HDF4054786.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVDKVKTEVDKLVEDGVKICDEVYTKVEKALGK"
     gene            28774..29646
                     /locus_tag="PC592_000778"
     CDS             28774..29646
                     /locus_tag="PC592_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HDF4054787.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQDEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSSVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLNKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            29681..30355
                     /locus_tag="PC592_000779"
     CDS             29681..30355
                     /locus_tag="PC592_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HDF4054788.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKVLGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNAENDCAWIKIYERLEAIGQLDNLVEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            30391..31272
                     /locus_tag="PC592_000780"
     CDS             30391..31272
                     /locus_tag="PC592_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDF4054789.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRVAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            31316..32701
                     /gene="lpdA"
                     /locus_tag="PC592_000781"
     CDS             31316..32701
                     /gene="lpdA"
                     /locus_tag="PC592_000781"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF4054790.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVIEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            32757..33527
                     /locus_tag="PC592_000782"
     CDS             32757..33527
                     /locus_tag="PC592_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4054791.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            33547..34491
                     /locus_tag="PC592_000783"
     CDS             33547..34491
                     /locus_tag="PC592_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HDF4054792.1"
                     /translation="MTFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NPPKIGIQISDVYPESWTDSYKELYKDVAKCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYSHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            34522..35889
                     /locus_tag="PC592_000784"
     CDS             34522..35889
                     /locus_tag="PC592_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HDF4054793.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDSKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRIALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            35939..36745
                     /locus_tag="PC592_000785"
     CDS             35939..36745
                     /locus_tag="PC592_000785"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF4054794.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            36802..38928
                     /gene="cdhC"
                     /locus_tag="PC592_000786"
     CDS             36802..38928
                     /gene="cdhC"
                     /locus_tag="PC592_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HDF4054795.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            39015..39392
                     /gene="gcvH"
                     /locus_tag="PC592_000787"
     CDS             39015..39392
                     /gene="gcvH"
                     /locus_tag="PC592_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDF4054796.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            39504..41432
                     /locus_tag="PC592_000788"
     CDS             39504..41432
                     /locus_tag="PC592_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HDF4054797.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTIFRKSDFKVTITYVQKQKKLTIINIEEGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            41457..42329
                     /locus_tag="PC592_000789"
     CDS             41457..42329
                     /locus_tag="PC592_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4054798.1"
                     /translation="MNKNLSEKVKVAFDIKLKNFGNKIEFAYPNQTLALSTTNNKCSL
                     KCAHCNGHYLNNMVPIEDYEEKVQSRNITSFLLSGGCSYDGDVPMSTHIQTIKRLKEQ
                     GYRLNAHLGLMDKESIIELCKYLDIVSFDLVFDKETIREVYKMEKSKDDYIEVYNTIR
                     ENTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIILIPTKGTEYENVEPPELE
                     RVADILCEARINLPYTEINLGCMRPRGVYRKELDQLSIMCGVNKIVLPSRSAKNKAIE
                     MNMTITECKECCVL"
     gene            42326..43264
                     /locus_tag="PC592_000790"
     CDS             42326..43264
                     /locus_tag="PC592_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4054799.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVVWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQINKFFSAGVDKIGIAIDAANKELYEKIKGNNYNEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKGNDITISLFAFTPVRGTKMEKIN
                     QPNIESYRRVQLMSYMINKGYSKEYFTFKNGYLDSIKLDNDIVKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            43311..44126
                     /locus_tag="PC592_000791"
     CDS             43311..44126
                     /locus_tag="PC592_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDF4054800.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLAKELYEKYKNEEYNKKR"
     gene            44277..44468
                     /locus_tag="PC592_000792"
     CDS             44277..44468
                     /locus_tag="PC592_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HDF4054801.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            44487..44903
                     /locus_tag="PC592_000793"
     CDS             44487..44903
                     /locus_tag="PC592_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HDF4054802.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            44919..45269
                     /locus_tag="PC592_000794"
     CDS             44919..45269
                     /locus_tag="PC592_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HDF4054803.1"
                     /translation="MIFDREIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            45538..46317
                     /gene="hisJ"
                     /locus_tag="PC592_000795"
     CDS             45538..46317
                     /gene="hisJ"
                     /locus_tag="PC592_000795"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HDF4054804.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDIGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKANL
                     NKYGEELEDSLLSVHIIKIDDDYYCVDYSIEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEDLIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDIV"
     gene            complement(46633..47508)
                     /locus_tag="PC592_000796"
     CDS             complement(46633..47508)
                     /locus_tag="PC592_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HDF4054805.1"
                     /translation="MKKRLIIILSLVLVLSSVLTIFAYSNIKYNNKLIYSNMIDKRTQ
                     NSVEEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPYNL
                     EKLQDNWMKKFPDYMDVNCRITAFRLFKDFINSNNKFTGDSIDLNVDLDTIMNNKDAK
                     FSTKDVEKFINFFSAIPAKDTSDISKIAEQIKNEWKKRKISFKNNKNISIINGFLRYP
                     ETKNVFIGHTGICIKTKNGILFVEKYGPTSPYQVTKFKNKKDVKNYMFNRLKMSESEI
                     ELPDPVIMENDKLMK"
     gene            48060..48572
                     /locus_tag="PC592_000797"
     CDS             48060..48572
                     /locus_tag="PC592_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054806.1"
                     /translation="MKVKKFKSGIVMALTVMVIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKVNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNVILREEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(48877..49974)
                     /locus_tag="PC592_000798"
     CDS             complement(48877..49974)
                     /locus_tag="PC592_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF4054807.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLNILEKYIIEHSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQDIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVDEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSRLEIKKVI"
     gene            50267..51793
                     /gene="glpK"
                     /locus_tag="PC592_000799"
     CDS             50267..51793
                     /gene="glpK"
                     /locus_tag="PC592_000799"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF4054808.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDKELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTNQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            51834..52949
                     /locus_tag="PC592_000800"
     CDS             51834..52949
                     /locus_tag="PC592_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF4054809.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGVIGGLIA
                     GFNLSMVIINMIPVIILSVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(53230..53994)
                     /locus_tag="PC592_000801"
     CDS             complement(53230..53994)
                     /locus_tag="PC592_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF4054810.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            54253..54343
                     /locus_tag="PC592_000802"
     tRNA            54253..54343
                     /locus_tag="PC592_000802"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:54287..54289,aa:Ser,seq:gct)
     gene            54431..55219
                     /locus_tag="PC592_000803"
     CDS             54431..55219
                     /locus_tag="PC592_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HDF4054811.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISDNN
                     ELDPFIKKGLELMVDGVDAVTIRSILESQIQITSKRHKEGIAIFDSAGGYAPTMGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            55240..55980
                     /locus_tag="PC592_000804"
     CDS             55240..55980
                     /locus_tag="PC592_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF4054812.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDNLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAVVKDNSREKIIQIGKMLNEMNSYIRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSNDK"
     gene            56158..56526
                     /locus_tag="PC592_000805"
     CDS             56158..56526
                     /locus_tag="PC592_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054813.1"
                     /translation="MGNKNTKYKDKTRERYNKKVENLNKEKLNKANKESKKVDKIDDI
                     INKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVKAL
                     FSIFVIVCFLIAFKYVVNPV"
     gene            56618..58078
                     /locus_tag="PC592_000806"
     CDS             56618..58078
                     /locus_tag="PC592_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF4054814.1"
                     /translation="MNRCKFAKLIITLMIVLLLTGCSLKKEDNYKLDPENPISIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGSERGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELSEYIDEYVEEGRINSKGEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFNGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLEVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDLNKINELV
                     KSGTSKKDAVAQFNNDKNFETWFESFKAELEKAIKK"
     gene            58131..61160
                     /locus_tag="PC592_000807"
     CDS             58131..61160
                     /locus_tag="PC592_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4054815.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEARINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIRIISNDLIYLLRKNSVTGAFIILSDKNIKDNPVDSNGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQEGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRIMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNDDMAFENVISNGYSLKEKFWNGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLNLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYVASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNADNVFCTKEFFSVFITESKFEEYGYMEK
                     SKFLKKLRGLDKYLQESYETENTYIYKFESKDKKPKWVRLNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKVAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSINYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGI
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            61237..63303
                     /locus_tag="PC592_000808"
     CDS             61237..63303
                     /locus_tag="PC592_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF4054816.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLKNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLISSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKVIKCSQGDGGSVTYISPHDSEEEAL
                     YIAKEIIDEIKKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    63831..64041
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            64265..65080
                     /locus_tag="PC592_000809"
     CDS             64265..65080
                     /locus_tag="PC592_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF4054817.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDSGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKNVTEGMAAAIKKADNNKEFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            65108..65785
                     /locus_tag="PC592_000810"
     CDS             65108..65785
                     /locus_tag="PC592_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF4054818.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            65844..66566
                     /locus_tag="PC592_000811"
     CDS             65844..66566
                     /locus_tag="PC592_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF4054819.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEVLLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT        26191 a         7399 c        12564 g        20791 t
ORIGIN      
        1 ggggatggcc tgtggagaat tagtaagaca tattttagta tgcaaaattc tgtgaagcag
       61 gaaccctgtg actttagtca tgggaggttc agatacttta tatatagcaa atattatata
      121 aagtaattaa agtattttaa gtatattaat cagtgcataa gttaatagaa atatcctaag
      181 tatagtaaat aatgtatatg ttaactcaaa tcaaccaagt ataaataact aatatataaa
      241 ttaactcaaa tattttaaac atagtaagaa atatgtaaat ttaatataaa tatttgagtt
      301 atagatataa ttatattaac ctaacaagta taaatagagg agaaaaatat gaaaaaaata
      361 gaattacttg caccagtagg ctcttttgat tcattaaaag cagcagttca aaacggagca
      421 aatgctgtgt atttaggtgg taaagacttt agtgccagag catctgcaaa taactttgat
      481 agaaatgagc tgattgaggc tgttaaatac tctcacataa ggggagtgca agtctttgtt
      541 actgtaaata cattgataaa acagtatgag atagaagatt ttgtagagta tgtaaaattt
      601 ttatatgata tagatattga tgctttaata gtgcaggaca taggaatggc aagacttata
      661 aaaaaactat tacctgactt tgaactacat gcaagcactc aaatggtagc acattcctta
      721 gaagatgtga aataccttca gagtgtagga tttgatagag ttgttttagc aagagaatta
      781 gatgttgatg agataaaatg gatttgtgaa aatacaactg tagatataga agtttttgta
      841 catggagctt tatgtgtatg ttactctggt caatgtctta tgagtagtat gataggcaat
      901 aggtctggaa acagaggtag atgtgcacaa ccatgcagac aaaagtatga gttgatagat
      961 ataaatacag gagaagtagt aaaaagtaac ggagattatc tgttgagtcc tagagattta
     1021 agtactatag aagatttaga taaaataatt gaagcaggtg tattatcttt aaaaattgaa
     1081 gggagaatga aaaagccaga gtatgtagct actgtggttt caggatatag agaagcgatt
     1141 aatgaatttg tagataagaa aaaaataagt atttctgagg aaataataaa taatttgtat
     1201 actatattta atagaaaatt tacaaaagga tatattttag gtgaagttgg taaggatata
     1261 atgaactcta atagacctaa taaccaaggt ctatatattg gaaaagtttt agattataat
     1321 agaaagaaca aaagacttag agtaatgcta gaaaatacgc ttaaaaaagg tgatggaatc
     1381 aacttaggcg gaggtactat tggaaggata ataaaggatg gagagataac tacaatagcc
     1441 cataaagggg atttgataga attagatttt gttggagaag caaagcgaaa tcagcttata
     1501 tataaaactt ctgatagcga attaatggat agagtacaag ctacattcca gcaagataaa
     1561 gagttcataa aaactaatat aagtgcaaaa gtgagtatta aactaggtaa aaaaccagaa
     1621 ctttttataa gtgatttttg tggaaataaa tctgtagtag aaggagacaa aatagttgaa
     1681 aaagctataa aggtggcttt aagtaaagaa aaaatagaaa cacaaattca aaagcttgga
     1741 aatacgccat acaagttaaa agagatagaa attgacttgg acgaaggtgt aagtatgcct
     1801 ataagtgtgt taaatcaaat gagaagagat tgtattgagc ttttagatgg agaaagaata
     1861 aagataaaag atagaaagtt taagaaaaat atattaaaat accagccaaa tagagtaaat
     1921 aaacagaaaa aacttaatac agttcctaag attagagtta aagtcaaaaa tttggagcaa
     1981 ttagaagcag tattaaatta tgatgtggac ttaatctatt atgaagatat aaatacatta
     2041 tcaaaagctt tacaaatggt ctcaagtatt tctatagatt caagtatttc tactgattta
     2101 gatacttctt cgtcttcaag tatttctaaa gaattaatgg gttcaaatcc aaacaacata
     2161 gatactttga ataataagcg ttctaataca gcagttactg acaagaaatt aatctattca
     2221 gcaccaagaa ttgtcagaaa taaagagtat aagcaatttg agatattgga taatataaaa
     2281 ggaattaata atgttcaaat tggtaactgg ggctgtatgg aatattttaa ggacaaagac
     2341 ttatatatag attgctactt aaatgcattt aatagtgaaa gtataaatca ctttaaagaa
     2401 gagggagcaa gtacagtttg tttgtcacaa gaactaaact taaatgaaat taaacaaact
     2461 ttaaaatata cagatgtaga aactgaagca gtaatatatg gatatgctcc tatgatggtt
     2521 acagaatact gtcctatggg agtagttgtt agagattgta aaaaggataa gagagttgct
     2581 aaatgtaagg aaagtaatta tgctttaaga gacttcacag atgcaagtta taggataaca
     2641 caagatgtat tctgtagaag tacaatttac aattcaaagg ttacttgtat gttggacaat
     2701 ttatgtgaat tagatgaaat tggaatagat gtatttagga tagattttac agttgaagat
     2761 agtgaaatgg ttaaaaaggt tattgaagct cacattgagg tcttgagtaa taattataaa
     2821 cttggggaaa aggctacaga cttgtacaaa aaattggatg aaattggaac agttgcagga
     2881 cactactata aaggtgtaga atagatataa catgaaaaat atacatgaat atatataaaa
     2941 acttgaattt atgtgtatta atatataaaa atatcatata tatgaaaaaa cagggggatt
     3001 agtgaaaatg agagaagaag ctttagaaat tttatttaag tatttagaaa ctgatagaat
     3061 gagaaaacat tgttatgctg ttgaagctgt catgagagac ttagccaaaa gattagagcc
     3121 agaaaaagaa gaagagtggg cagtggcagg tcttttacat gatttggatt cagatatagt
     3181 tggaagaaag ccaggagaaa tatgtgaagg acatgctaca acaacagtag aactgcttaa
     3241 aaaagaaaac ttcggtgatg aagaaatgta tagagcaata cttggtcatc atgatgggat
     3301 gggagttaca agaactagcc taatggaaaa agcaatatat gcagcagacc ctataactgg
     3361 ctttataact gctatagctt tagtttatcc agataaaaaa cttactagtg taaaaactaa
     3421 gtctgtgatt aaaagaatga aagaaacgag atttgcttca aatgtaaata gagatgcaat
     3481 gagaagtata gaagatatag ggattccatt tgatgaattt gcagagcttt ctcttaatgc
     3541 aatgaagaat ataagtgatg tgcttgaaag tgctgaaaat aattagttta gaatataaag
     3601 agaaagtaag gcgagatata tgaaacttac aactatttgt tatatagaaa aagatgacaa
     3661 gactttgatg ttgtacagaa ataaaaagaa agatgatata catgaaggta agtatgttgg
     3721 agttggagga aagtttgagc aaggagagac tccagaagaa tgtgtaatca gggaagtaaa
     3781 agaagagact ggtcttactc ttaagtcttt gtcatataaa ggattgataa cttttccaaa
     3841 atttaaagat gaagaagatt ggtatatgtt tttgtatttc tcagatgaat ttgaaggtga
     3901 attatctgaa aaagatttaa atgactgtaa agaaggaaat ttaatttggg ttgataatga
     3961 taaaatattc gatttaaata tgtgggaagg cgacaggttg ttcttaaatt gggctaagac
     4021 aggaaacatt tttagtgcaa agattgtata taataatggg aaactaaaag attataatgt
     4081 aagtttctta gattaattaa gattgtagtt tttagattaa ttaaggtgta gtttcttaga
     4141 ttatttaaga tagagatatc aatgcaagta tcaatctact aaacttagcc atataaatgg
     4201 caatcataag agctaggaac tagcctaata gcttggagat actgataaca atagttactt
     4261 gaacaagaag ccaccacttc aaacattacc gtaggtagtt aagtggatgg tagttcacat
     4321 tgattggcat aatattaaga taaataacat tagttgagaa aaagggttat ctcaaaatag
     4381 agataagcct tttttattgt tgaaatgata aaaatacctt gatttcacac aataaagaat
     4441 atctcatcaa ctaaaaagtt cactttgtga cacctacttt tcttatcttt cattttgaat
     4501 aagttctaat atatatttct caattaaagt gtagttaaga ctaatatatt gttaaaaaaa
     4561 taaaaattga cttagacaac tatttgtttt atactaaagt aaatttttta aaaggaggaa
     4621 taatttggaa tgatagacat aaatttagaa aaatgtgtag gctgtgggat gtgcgaatca
     4681 gactgtcttg taaatgcaat aaaagttaag gatgataaag caaaggtgaa aaatattctc
     4741 tgtattaact gtggtcactg tatggcaatt tgtccaacag atgcaataga aatgcaggga
     4801 tttgataaaa atgaagtagt agaatacaat cgtgaaagtt ttgaattaga gcccgaaaag
     4861 ttattgaatt ttattaaatt tagaagaagt ataagacaat ataaagatat agagatagaa
     4921 gaagaaaaaa taaaaaacat agtggaagct ggtagataca caccaacagg tgggaataga
     4981 cagcctataa gatacatatt agtaaaagaa aaactaaaag aagtaaaaga actagcaata
     5041 gagggtctct ataatttagc attaaatact gatgacaatg accccgtacg ttctatgtat
     5101 aaaaacacat ttaagaaaat gtacaaaaga tataaagaga acggaaagga ttctttattt
     5161 tatgatgctc ctctacttat ggtagttgta ggtgatatgt ctctaggtgg aagtgcttat
     5221 gtagatggag gattagctgc atctaatatg gaacttatgg cttattctca aggattagga
     5281 atttgttata atggattttt tgttatggca tcaaatgtag agccaaagat aaaagaattg
     5341 ttaggaatga gcgagaatga agcagttata acttcattta tactgggtta tccagatgtg
     5401 aaatataaaa gaactgtaaa tagaaacact gctaaatttg aggttatata gaatttagcc
     5461 tcactacaat ttgtaaaatt atgggatata gggtaggtat ttagcagggt aaatttgttg
     5521 taatagatat ataaatgagt tataatttaa atatatagta tatattaagg atatttaaat
     5581 ttctgagtaa atttatatat ccttttatat actaatctat tttttcatgt ctacaagttt
     5641 atgcagtaat ttatactgta aatcttaact atatggagga ttgtgtagtg aatttaaaaa
     5701 aattactttt attaattatt gtaattacat ctatattcac ttcttacata ttttctttta
     5761 gtatcaatgc tatagctaat gataatcgta ctattcggat tgcttatcct attcaaaaag
     5821 gtctaactga aatagatgag caaggtaact attatggata tacatatgaa tatttactag
     5881 aaattgcaca gtatactgga tggaattatg aatttgttca agttcctgga gatataaatg
     5941 aatctattac aaaattaatg aagatgttag aaaatggtga aattgatata atgggaggta
     6001 cattatacaa tgagtcattg caaaaaatat ataattatgc agggaatagt tatggagtag
     6061 caaatacagt actacaagca ttatatgaaa atacagatat tgataacata atgagttctc
     6121 aaggtgtaaa aaaaattcgt attgctgtaa tagaaaattc tgatactagg cttaaggagt
     6181 tagatgagta ttgtaagatg aatttgatgt cacctgaatt ggtatactgt aaaacaaatg
     6241 aagaacagtt agaagcacta aagaatggta aagcagatgt acttcttaat gtgagtatga
     6301 atccaataga agatgtacgt actgtagcaa aattctcatc aagaccgttt tatttcatta
     6361 ctcctaaagg tagtacagac ttaactcaaa gactcaattc agcaattaat aatattgaac
     6421 agaaggatcc atatttttca actactttat atgagaaata ttttacacca gagaataatc
     6481 agatgttttt atctgatgaa gaaactaact acattaaaga tacagaaaag ttaaaggtag
     6541 gagtactttt aaataaacca ccatttcaaa atatagataa aaatacaggt gagttaaaag
     6601 gtatatcaat tgatttgtta aatcacatat gcgatttaac agggctagaa tttgaacttg
     6661 tacctataaa atctcaaaaa gatttggaaa aaatgaccaa aaatcatgaa attgagattg
     6721 tagcaggaat aatttatgat tatgaatatt ctcgtaaaca taatataatt atgtctcgac
     6781 catttgtttc tactcaatat gctatgatga ttaataacaa attaaatgag aatagtcttg
     6841 atggaaaatg tctagctcta actagaggac ttaattatga gggtcagttt aaagagaata
     6901 ttgtgtggta tgatacttta gaagagtgta tagaagctgt taataaagga gatgtagatt
     6961 atacttatgg tgaaggttat tctatgcagt actatatgaa tcaacctaag tataaaaatg
     7021 tgcgtctagt tcctcaaact tatgaagcac agagtatttg ttttgggata attaaaaaag
     7081 ataaacaaga attactgaat atatttaata aagctattac aagtatttca tcagaaaaaa
     7141 tgcaatcaat tgtctaccaa aatactacat atagacaaga tttttcatta ctttatatta
     7201 tgcaacagaa tccaattgag actattttta ttgtagctag tttgttaatt tgtattattg
     7261 gatttatggc atttggttta catactcgta cgagtatgaa cgagaagata tctttggaac
     7321 tcaaaaaaca tactcagttg tatgaaatga caagtgaata tttttttgag tatgattata
     7381 agcaagataa attgataatt tctatgccag aaaagggtat tgagacttat tatggtttag
     7441 ataaaaatga tagggaaagt gaaaataaca acaatatagc aaatgaaata gataaaataa
     7501 gaagagaata taataaaaag ttttttgatg taataaaatc acaagaaaat ggaacgactg
     7561 aaatgtattc tattgtgttt gatgatactt ttcattggat tagaattact tcaaaaataa
     7621 tttataatga tagaaaaata ccaatgtatg taatcgggaa aatatctaat attgattatg
     7681 aaaaagagga aaagaataga ttattagata aagttcaaag ggatagttta accaatattt
     7741 ataatgcagc atatattaga aaactaactg cacaaaattt attgaattta tcaactgaaa
     7801 aaaatggtgc tttattgatt atagatattg attattttaa gtcaattaat gatacttatg
     7861 gtcacctggt aggagataaa atactgattg acgttgcaaa ggtacttgat gaaagtttta
     7921 caaaagatga tatagtaggt cgtttaggtg gagatgaatt tagtgtttat atcaatgata
     7981 taataaataa tgaagaactt atcaataagt gtaatgatgt atacaatcgt attcatctca
     8041 ttaaattgcc aaatggaaaa agtttgtcta ttagcatggg ggtagttata gcaaagtgtg
     8101 gtcaagagta tgatgaactg tatcaaatag cagataatgc tctttacgat tctaagagag
     8161 aaggaagaaa tagatttaaa atagtataag aattaatttt aaaacagaat aaagcttaat
     8221 aatatttaaa ttacaataaa gcctaatgat acatgttact atctatcatt aggctctatt
     8281 tctataagtt aatattgaaa gtaaatgtta tactaacagt agtattaact tacagagtta
     8341 attttatata gattacttaa gactaaaatc tatttagaat caaaacttaa atttaatatt
     8401 ggttcataga ttttaatatt tcaataacat aatcccaaat attagctaca gaagggatac
     8461 taacatgttc atttggagta tgaacatcaa acatatctgg tcctatagag atagcttcag
     8521 catgaggaag tttatcaagt aataatccac actcaagacc agcatgtaga gccataacag
     8581 taggaacttt accagttaat ctctcataag tttcacagca tattttttct aattttgagt
     8641 cttttttaaa ttcccaagct gggtattgag ctataaggtc gtaattagca cctaaagctt
     8701 gagctaaaag tcttattcta tcagcaattt catctctaat agacataaca gaacttctaa
     8761 cagaagttaa aaattcaata gtagattctt tagtttcaat tatagcgaag ttagtagaac
     8821 tttcaactaa tccttctata tcaagactta ctgattgaac tccatgagga gttaagcaag
     8881 acatttgaac aaccttttct ttacaatctt tagtaagaac tttgtctaca gaagtttcag
     8941 ctactgagta agtcatgcca gggtcagaag tagtgaactc atgtttaaat gcagttaaaa
     9001 tgtcatttat ttgtttttta gcagattcaa catcagcttt attaacagct attacacact
     9061 tagcttcacg aggtatagca ttgtgcttag taccaccatc aacagaagct aattcataat
     9121 caacatctaa tacacttaat actctagcta ttgctttgtt agcatttgct ctttgtaaaa
     9181 caatttccat accagagtgt ccacctaata atccagtaac ttcaactaat aatccttgtt
     9241 tgtcaccttc aacctttttg tattcaacag gtaaactaac aacacaagtt ttaccaccag
     9301 cacagctaac taataagtat ccttcctctt cggagtccag atttaggata tattgacctt
     9361 taattaagct agggtctaat gcatcagcac cattcatacc atcttcttca ttaacagtaa
     9421 ttaaaacttc tagtgcagga tgctctaaag tattatcttc taatatagcc atacccatag
     9481 caacagctat accattgtca gctcctagag tagttccagt agcatatatc atgtcaccat
     9541 caattcttaa ttttataggg tctttaagaa aatcatgttc aacattcttt tctttttcgc
     9601 aaaccatatc catatgtcct tgaagaacta cacctggaca attttcatat ccttttgtag
     9661 caggctttct tattattatg tttaagcttt catcttgaat agtttcaaga cctaaatttt
     9721 taccaaagct aagtaaaaaa tcacttatgc ccttttcatt tccagaacct ctaggaattt
     9781 gagatatttt ctcaaagttt ttaaaaacac tttctggttt taatccttct aatacgtttc
     9841 ccatgactca tgttcctcct taatttatct atataagtag ctattttttt ttaagctaaa
     9901 ataaactcct ttaaaaatat taaagaagat tttttaacag attatattac aaataaagca
     9961 tgtttatgta taatatatag atagctacat acatagtata atacaaaata tgtgtaaaat
    10021 atatctaaaa gagaaaaaat ataataattt tagaaatgaa aaagaaataa aacttgcagt
    10081 ttttattgga aatgcttgaa aacatacatt tttaaaatta aataaaaaag ttaaaatatc
    10141 gaggatggtg aatatagaaa atgaatgaga aatcgttaag agttctagaa tacaataaaa
    10201 taatagattt gttaaagaag aaagcctcat cttccttagg tctaaaatat atagaaaatt
    10261 tagtaccaaa tactgatttt gtagaagtga aatctatgct agaagaaact agtgaagctc
    10321 aatcaattat tataaagagg ggttcagtag gcttggaagg tattcatgat atagaagaca
    10381 aggtaaagag agcttatata ggtgcttctc ttgacccagg aagtctgatt atgatagcag
    10441 atactttaag agtggctaga agattaagaa atagcttatc tagcagtgat gaagaagatt
    10501 ttaattatcc aataatacaa tctctatcaa attctctata tgtatataag gacatagaag
    10561 accagatata caatgctata attagtgaag tagaaatatc tgacaatgct tcaagtacac
    10621 ttagagatat cagaagaaga atagctcaaa aaaatcaatc cattaggtca aagctaaatt
    10681 caataataag ttcaactact tatcaaaaat acttacaaga tgcaataatt tctctaagag
    10741 gtgatagatt tgtagtacct gtaaaagctg aatataggtc gcaagtagct ggtatagtgc
    10801 atgaccagtc atcttctggt gcgacacttt ttatagagcc aatgactata gtagagatga
    10861 acaatgaatt gagacagttg aaactaggag agcaagaaga aatagaaaga attttatcag
    10921 agctttctgc tatggttgga gaagtgagtg aagatttaat ctcaaatcaa gagatacttg
    10981 gaagattgga ctttgcattt tcaaagggaa aactttctat acagatgaga ggaatagaac
    11041 caactttaaa tgaggataaa tatttaaaca taaaaaatgg aagacatcca ctgttggata
    11101 aaaagaaagt agtagcaaat acgatttatt taggaagaga tttccacaca ttggtgataa
    11161 caggtccaaa cacaggtggt aagactgtta caataaaaac tgtaggtcta tttgcactta
    11221 tgacacaaag tggacttcat atacctgctg attatggaag tagtatgtgt gtatatgata
    11281 atgtatttgc agatatagga gatgaacaga gtattgaaca gagtctatca acattttcat
    11341 ctcatatgac gaatatagta tcaatattac aaaacgtaac aacagactcc ttagttatat
    11401 ttgatgagtt aggagcagga acagaccctg ttgaaggagc tgcccttgcg atagcagtat
    11461 tagaagatat aaattctgta ggagctaaat gtatagctac cactcactat agtgagctta
    11521 aaaattatgc tcttactaaa tcaggtgtag aaaacgcagc agttgaattt gatatagaaa
    11581 ctttaagccc gacatataaa ttacttatag gtgttcccgg aaaatcaaat gcatttgaaa
    11641 tttctagaaa acttgggcta agtgattatg tgatttcacg tgctaaagaa tatataaata
    11701 cagaaaacat agctttagaa gatgtgttac agaatgttga aaaaaataga atcaaagcag
    11761 tagaagatag agaagaagct gaaagattaa aagaagagat tgaaagactg aaagtagagt
    11821 atgatgaaaa acttgaaaaa ttggttagtc aaagagataa gatgattgaa aaagctaaat
    11881 cagaagcatt ttcaattata agacaagcta aagaagaagt agacattata ataaaagaac
    11941 ttagaagtct tgaacaagaa cgagcttcaa aagaaaagaa tcgtaagata gaagaactta
    12001 gaaaagaatt gactagttct atgggaagtc ttcagccaac cgtaaaaagt atgatagttc
    12061 caaaggtatc aaataaggag ataaaagact taaagccagg tgaagaagtt aaggtaataa
    12121 ctttaaatca aaatggtagt gtagtttcag tagataaaaa gagaaaagaa gcagtagtgc
    12181 aaattggtat aatgaagatg actctacctt ttaagtcttt acaaaaaaca cacaaagatg
    12241 tttcaacaaa tgtaaccaaa tcaactagaa atattataag gtcaaaatct ggtagtgtaa
    12301 aaaatgaagt tgaccttaga ggattaaacc tagaagaagc tataatggaa gtcgaaaagt
    12361 atcttgatga tgcatatgtg gcaggtttag agtctgtaac agtaatacat ggaataggta
    12421 caggagtatt aaaagcaggg ctacaagaca ttttaagaag aaatagacat gtaaaatcac
    12481 aaagaggtgg tcaatatgga gaaggtggag caggagtaac aattgttaaa ttaaaataat
    12541 ttgtataaga atacattagt aatttgtatg agaatatatt aataatttgt ataggagcac
    12601 atttttatga tattggtatc tgcatgttta ataggaataa attgtaaata tagtggcgat
    12661 aataatgaaa atgaaaaagt taaggaatat ttaaaaggca aagaatttac acttgtatgc
    12721 ccagagcagt taggtggtct atctacacca agaccacctg ctgagatagt tgatggaaaa
    12781 gtaattacta aagataataa ggatgtaaca gaaaactttg taagaggggc taatgaaact
    12841 ctaaaaatag caaatttata tgtatgtagc gaggcaatac taaaagaggg tagcccctct
    12901 tgtggatgta atctaatata tgatggtagt ttttcaggta aaaagatacc aggcaaaggc
    12961 ataacggcaa gattactgga agaagaagga ataaacgtta agagtgaaaa agacttatag
    13021 caaattaaca ctgatgcata aaaaatgata aaagagtaaa aaagtatata aagtcaacat
    13081 tgatgtatga aaaatggcaa aagagtaaaa aagtatgtaa attcaaacgg gtagtataag
    13141 aaacaataag atagaaaaaa gtttataaaa aaccaataat cgtgtgatta aaaattgtaa
    13201 ttatagtatt tttaatatat acagaaaaca taattattaa agtgttttgc actgtaatga
    13261 aatacttgaa aaaacacgaa atttgattta acataaagag ataagcacaa tataaaccag
    13321 gaacaatgta gagaggagca acagaatgca agatttcaag gtggcaatat caaattgcct
    13381 taaagaaaaa atagaagatt tatcgaaaga agagatagag gcacttatag aagttccacc
    13441 aaataaggat atgggggact atgcttttcc atgctttaaa ttagccaaag tgtttagaaa
    13501 agctccaaac atgatagcaa gtgaattggc ggaaagtata gaaccaagtg gagagataac
    13561 aaaagtaata caattaggcg gatatgtaaa tttctttgta aataaatctc aattagcaga
    13621 aactgtaatt aaaaaagttt tagatgaaaa agaaaattac gggcatagtg attttggaaa
    13681 agacaaaact gtaatagttg aatattcttc tccaaatata gcaaaacctt tccatatagg
    13741 gcatataaga actacagtta taggtaatgc tttatataag atatatgact cacaaggata
    13801 taagactata agaataaatc atttaggtga ctatggaact cagtttggta agttaatagt
    13861 ggcctttaaa aagtggggag aaaaagaagt agtagagtct aatccaattc cagaattact
    13921 aaaattatat gtaagattcc atgatgaagc tgaacaacat ccagaaatgg aagatgaagc
    13981 aagagcatgg tttgctaaat tagaaaatgg tgatgaagaa gcaaaggaat tatggcaatg
    14041 gtttagagat gagagtttaa aagagtttaa cagagtgtat aaacttttag atatagaatt
    14101 tgattcttta gcaggtgaga gtttctattc tgataaaatg aacagggtta ttgaactact
    14161 ggaagagaaa catcttttaa aagagtctaa gggagcaaga attgttgatt tagaagagta
    14221 taaaatgcca ccagcactta ttactaagaa tgatggttca acattatata tgacaagaga
    14281 tttagctgct gcaatatata gaaaagaaac ttatgatttt gacaagtgta tatatgtagt
    14341 tggttctcaa caaaacttac atttccaaca atggtttaag gtaatcgagc ttatgggata
    14401 tgattgggca aaagacttaa ttcatgttgg atttggtatg gtagctcttg aagaaggaac
    14461 tatgtcaact agaaaaggaa gagtcgtatt tttagaagat gctttaaatc aagctataga
    14521 taagactaag gagattatac tagcaaaaaa cccaaatgcc aaaaacgtag atgagatatc
    14581 taagcaagtg ggtgttgggg cagtagtatt ccaagagtta tctaatagta gaattaaaga
    14641 ctatactttc tcttgggaaa gaacgcttag ttttgatggt gagactggac catatgttca
    14701 gtatacacat gctagatgct gtgcagtttt aagaaaagca gaagtagaag tgacttctga
    14761 tatagattat agtctattag ctgatgaaga tagtgcagaa gttcttagag ttatagaatc
    14821 attcaataag aatattttac ttgctttaaa gaaaaatgag ccacatatag tgactagatt
    14881 tatgctagat ttagctcaag cgtttaataa attttatcat gacaatccaa ttttagtaga
    14941 aaatttggaa ataagaaaag caagacttgc gttagtttta gcaacaaagc aaactttaga
    15001 aaattctctg agattgttgg gaatgcatgc tccggaaaga atgtagcatg acaaaatgtt
    15061 gaaataaaaa gaataaaatt gaacttagta cgcaatttgt ataactgtaa aatataggga
    15121 tgtcgaaaac tgatgcttta catataaaaa agtagtatcg tataataata tatagatagt
    15181 agattacaat gatttttgta cactactatc cccctatata tgacagcttc ttaaatgggc
    15241 tgtctctttt tttttaataa caatttattt acattcaatt tttcagaaag gatatattta
    15301 tgaatgacga attactaaaa aaagtctata catcttcttt tagtagtgca agtagggctc
    15361 ttaaagattt gattataata aatacaaaat ccttaataga tgataaaacg caaagatgtg
    15421 tgtatataga cgaaaataga ctgagagatg aacttattta ttatagattt tatggagaaa
    15481 aaataggcaa tatcaatttt ttaaatattt tattaccact aattttatca aatactaata
    15541 ttcaaaaaag cgaagatgag gttattaaac taataaaaaa atatgttact tattttaaaa
    15601 aagaaaaact tttatttgag tatttattaa gttctgtagt gtataattcc attatgcaca
    15661 atcttataaa taatagtaaa atagaatatg tcgaattact acagagtatt aaagacaaga
    15721 taataggatt ttctatagaa ttagacaaat cagatgttgt aaagtttcag atggcaagga
    15781 ttaaagcaat acaattaatt gataaatata ttgatttgaa atttgaagat tatgatgaag
    15841 aaagtatttt attaaatatt ttaaatgttc tatatgatgt atatatggaa gatagaactg
    15901 tagaagatga aggaattaat agcataaaaa aatctatatt atccatccta ggtgaagata
    15961 gtaaattaaa tgaagataat atagatttta ttttttctat gtctgaatat gtagttaaat
    16021 tgagaaaata taaaattgga gttaaggcat acaataaaaa aatagaccca agaagtctta
    16081 taagacttga agaaggtaat actataatag accccatatt taatcaaata acagttatat
    16141 caaaaacctt taatgataat atattaagca taaaaataaa ttctaaatca ggtatttata
    16201 tattaaagtt taaaaaggtt taggtgatta gagtgtgcta tttttttcta gataatctaa
    16261 aaaatctttt tccttagtgt cagttaaaaa acataattcc tttactatat tattcctaag
    16321 gtcaatgaaa tcactaattt gagtattttc attagtgtat tcaagagact ttataataag
    16381 tagtaaatct ctttttgata aagagttgat agatactttt tcaattaatt ccataaaaaa
    16441 cttcctttcc tcacattact tgaaattaat aaattaatta tatagatatt atttagactt
    16501 tacatatact attttaacct ataaggggta caaaaagaca gtataatctt aaaaagaggt
    16561 gagaaatatt tgaaaatttt attaacaaca ttaaattcta agtttattca tacaaatttg
    16621 gctataagat atttaaaaga atttgtaaga gatttgatag aagttgatat gaaagaatac
    16681 acgataaaca acgatttgga ctatattttg aaggatatat ataaaaacga atatgatata
    16741 atattgtttt caacatatat ctggaatgtg ggagacatag ttaagctttg cgataatcta
    16801 aagaaaatta gacctaatac taaaatagct ttgggcggac cagaagttag ttatgatagt
    16861 tatgatgcaa tgaaaaagta tgattttgtg gattatatac tttatggaga gggagaatta
    16921 atttttagag acttagtact tcatttgcaa ggaaagatgg aaataaatga tgtaaatgga
    16981 cttgtatata gacaaggcaa tgagataata gtgaataagc ctatggaatt acttcaaaat
    17041 ttggatgaga ttcctagtcc ttatgaaaat ttgaatccaa gagaatatga aaatagaata
    17101 gtgtattatg aatcatcaag aggttgccct tttaactgcc agtactgttt atcatctact
    17161 attccaggtc taaggtattt tagtttagag aggataaaga gagatttaaa agccttaata
    17221 gatgcaagag tatcacagat aaagtttatt gataggacat tcaatgcaaa tagaaaagtg
    17281 gctatggaaa ttatggattt tcttatgaaa aatgataatg gatatacaac ttatcatttt
    17341 gaagttacag cgtatttgat agatgataag atgcttgaat ttttggctga ttgcaaagaa
    17401 ggtctttttc aatttgaaat aggtgttcag tcaacgaatg aaaaaacact tgatgcagta
    17461 ggaagaagag atgattttaa aaagttgtcc catgttgtac agactgtagc atcttataga
    17521 aatatacatc agcacttaga cttaatcgca ggactgcctt atgaagatta taagagcttt
    17581 gaaaattctt ttaatgatgt atttaatcta ggtatagaac atctacaatt aggattttta
    17641 aagatgatta aagggacagg tatgagaaaa gttgcagatg agcatggttt caaatataaa
    17701 gattacgctc catatgagtt tttatacaat aattatataa gctatgaaga aactttgaag
    17761 ctaaaggata tagaagatat actggagaga tactacaatt ctaaaaattt tgtgttatct
    17821 atgagatata ttataggcag attttataaa caaagtcctt ttaaattctt tgaagttttt
    17881 gctaagtact ttgatgaaaa tggctacttt gatttggcac aaggaaagaa tcaattatat
    17941 aaaatattga tggatttcta taatgaaaaa atcaatatag ataatgatgt attcaatgat
    18001 atattaaaat atgactatat atcactgggc aaaacatcaa atataccaca gttttttaat
    18061 aagctagatg tggatgattt taagaataga tgccatgtat ttttacaaga taatgataac
    18121 ttatcaacat atttacctag ttttgttgat aaaccagcta agcacataat aaaatatgtt
    18181 cattttgagc catttagatt taatgttgtg gatttaaaaa atgatataaa tacagaaata
    18241 agagaagcag aaaatgtagt cttatttgag tatgatgata aaaaaatatt tgagaaatct
    18301 aaaactcata aagtagagat ttaagtattt gggaggataa aatggatttt aagatagaaa
    18361 aatatttgct aagaaaagca gaggaattag cttttataac tataaaacat ggtggagagt
    18421 ttaaattaaa aagctatgaa gtaccaaaag gtggattaga tgtacctata aaaaacgagg
    18481 tattagtaaa aggcataaaa gaaaagactg ctcaagataa gttaaattca atgtctatag
    18541 cagatgcaat gatatatata attgggatag atagtaagtt taaaaacaat gcagagtatg
    18601 agaagttttt aaatgcttta tcaaaagata ttgatttgga tttgaaagcg tatatgggat
    18661 atatgtcgag aaaatacttt gaaatcggtg aacatacaga ttctttaata tatataaaag
    18721 catttataac aatgtatcca gatgatttag atgcaatgta taattatgcg attgtttgtc
    18781 aagagatagc aaaacagtat caaaaagata tggatgataa ggcaatgaat gcattcttac
    18841 ttgaagcaat ggctaagctt gaagaggtaa ttgatgttga tgagaacttt gcattaggtt
    18901 attatcactt aggctaccat tattataatc aaggtcaata tttaaagact aagttgactt
    18961 gggaagaggc gttaagacta gggctagatg ctgatttggt agctgagata caagagaatt
    19021 taggcaagat ggattttaaa gttcaatatg aagaaggata tacacttgta ttccaaggta
    19081 agtttaaaga aggattagaa aagttacttc cattagaaga agaacatatg gattggtgga
    19141 acttgctgtt catgatagca cttggatata agggtatggg cgaaatagaa caggctaaga
    19201 tgtatcttga gaagatatta ataataaagc ctaatcaggt ggatactata gtggaattag
    19261 ggctttgtga ggcttataag aataatctag ataaagcaat agagtatttt gaacaagcag
    19321 ctaagataaa ggaagaccca gaaatacttt gcaatttagg aatggcttat ttaaataatg
    19381 gtgatattga tgatgcaact tactatatag aaagagctta tgaattaaat ccacaagatg
    19441 aaattacgat tgcttgttta agagagcttg gaataaataa ataaataagg atattgttag
    19501 gttgtatttg attttattgg ttaaatgagg ctgtctcaaa atagagataa gcctcttttt
    19561 attgctgaaa tgattaacat atatttgact tcatacaaca aagagccatt atgaagtaaa
    19621 aagttcattt tgagacacct taatttttta ttattattta ttttacttca ggtgtattca
    19681 acttagatat atccaactca gatgtatcca acaggataga agaaaaatct ttttgtatct
    19741 gaagtaaaaa tttttctgct gcttttgaaa atatttgatg ttttttccat ataatattta
    19801 atttagcttc taaaggagga gatagaggtc taaaacaaag gttactattt tctgtagtat
    19861 tgacgagtct atctaaacac agagcatagc ccagaccttc ttctaccaaa agagaagcat
    19921 tataaactaa attgtatgtt gcaacaatgt ttagtttttc agtactgtct tgaagccatt
    19981 tagaaattgc tttatcaacg agtgtctgtc ttgaaataat aagaggtata ttgcataaat
    20041 cttttggatt tatcgtattt tgtgatgcga gggtactatc tttacgcatt agtaaacccc
    20101 atacatcagt agcaggaatt tgtgtataat catacttctg tatatttgca ggttcaatta
    20161 aaataccaaa atcaagaagc cctttgtcca atttttcagt tacatcatca gcattcccac
    20221 taaaaaggtg gtattttaca ttgggatatt tttgatgaaa attatgtgca gttctagcta
    20281 taagtctcat agcttcagtt tcaccacctc ctatatatat atcaccacta ataatttcat
    20341 tgggattgtc aaactctaat tcaactttat caactaatga tataatttct tctgctcttt
    20401 tatgtaaaag tttaccctcg tttgttaagg tgatttttct atttcctcta accaataatt
    20461 taactcctaa ctcttcttca agttctataa tctgtctaga aagtgttggt tgtgttatat
    20521 gtaaaaaggt tgctgcacca gatatacttt cttctcttgc aattgctaaa aaatatctca
    20581 atactcttat ttccataatt atcactcctc aatattaatt tgtttattat atgattatat
    20641 caattattat gctttttaag tatagttaag tatttaatat agatatttga tatagataga
    20701 attatatatt acactaaaag gagcaataat attgcctaaa aaataaatta aattagttat
    20761 tattaaaata ttatttagaa ggtacaaata aattaaagcg catattgaag ggatgtataa
    20821 aatgaatatc aatgaatttt taacacatgt caatcaagga aagcccgtct ctagtaaatc
    20881 agaaatacat aaatttatgg ttaagttgag taatgaagct atgagaatca caagtgagtt
    20941 aaactcttat tatcatgaac cagaagaaat ccatagttta ttttctgagt taattggaaa
    21001 gaaagtagat gaatcatttt ttatgtttcc accattttat acagattgtg gaaaaaacat
    21061 tacaatagga aaaaatgttt ttataaatag cagttgccat tttcaagacc agggtggtat
    21121 tgagattgga gataacactc aaattgggca taatgtggta ttggctacac ttaaccatgg
    21181 cattgcacca gaaaaacgtg gtacaactta tccttctcca atcacaatag gaaaaaatgt
    21241 atggattggt gctaatgtaa ctgtagttcc aggcgttact ataggagata atgcaattat
    21301 agctgctgga gcagttgtca caaaagatgt tgcagaaaat actattgtag gtggtgtccc
    21361 tgcaaagatt ttaagagtta ttgataaaat cacagaataa aatattaaac ggtcttttag
    21421 ttatataaat tctttataac ataaaaataa attgagaaaa ggtatattaa atatggtatt
    21481 atttagttaa atatatataa gggaggggtt acttttgata aaaaaattag atgatatttt
    21541 agaccaactt aaaggaggag agaaaattgt actctctgta gcagcagctc atgataaaga
    21601 agttttaatg gcaataaaag atgctgtaga aagaaatata attactccta tattggttgg
    21661 aaatgaaggc aaaataagag aaatatcaaa agaaatagga tttgatttaa gtggtatcaa
    21721 aatagtggat aaggatgata tcaaagagtg tgcagaaata gcagttaaat tagtatcaag
    21781 taaagaagcc gactttgtaa tgaaaggatt attagataca tctgtcatat taaaagaagt
    21841 tttaaataaa gactatggtc ttagaactga tagtttatta agtcatgtta tggtatatga
    21901 gttagaaaaa taccataaat tacttataac tacagatgga ggtatgaata tagctcctga
    21961 ttatgaacaa aaggtaaaga tattaaaaaa ttctataaaa gctgcaaaag ctttaggaat
    22021 ggaaactgta aaagttgcgt gtttggcagc taaagagaaa gtaaatccta agatgcaagc
    22081 aactgtagat gcagatatgt tagcaaaggc ttgcaaagaa ggagaatttg gtgacaatgt
    22141 aattgtagaa ggtcctctgg cttttgattt ggctgtttca aaagaagcta gtgagataaa
    22201 agggtttaaa agtgaagtat ctggagatgt agatatcata ttggttccaa caatagaggt
    22261 tggtaatgga atagggaagg cctttacata catggcagac tctaaatcag caggtataat
    22321 tatgggtgca aaagctccta tagttttagt gtcaagagct gattcacatg aatctaaatt
    22381 atattctatt gcatatggtg ctattgtagc taaaaatatg aaataggata aatattttga
    22441 aataaataaa ttaaagtaga aaaaatagta aaaatgtcta aattaatatt gtattaaaaa
    22501 aattttatat aaaaaataat tatagcttca aatgaatata tacaaatgtt caatttgaag
    22561 ctataattaa tattaaagta ggaaaaataa aaaaattcaa aaaaattagt ccaaaaaatg
    22621 ctattctaag aagtttttac taattaagtt tagggagcaa aaatctgtaa taagtccaaa
    22681 tagtagtgaa agataataaa tacacaaaca atctgtaata atataaaaat gactagaaaa
    22741 atttcaaatt tgatttaaaa aaatcaaaac ataatttaat taaactgaag tatcaaaaaa
    22801 gtaggtttag atattaacaa atagccaaaa ataagcgata aaatcaactt aaattaagta
    22861 caaaaaataa aatttttatg tattatctaa ttttgttaaa aaaatattta aatctaaagc
    22921 aaagcactga aaattagtat ataatcaact tagaaagcat ttattttatt attttatgac
    22981 atgaagtcag tcacctgggg gattttaaaa atcaaaaaaa ggggatagga atatggatga
    23041 aaaaatgtta acaattgatt taaacagcca gaagatgata gctaaagcta gagaagaagg
    23101 cgtagaaaca atgtatgata gaaaagaagg ctttaaggca caatgtggtt ttggtcttca
    23161 aggtgtttgc tgtagaatat gtggaatggg gccatgtaga ataagcccta agactccaag
    23221 ggggttatgt ggagcagatg agcatactat agtaggtaga aactttgcaa gaatggttgc
    23281 tggtgggaca gctgcccatt cagaccatgc tagagatata gcacatacat tagcattagc
    23341 tgatccaaat ggaaactata aaataagaga cgaagctaag ttaattactt tagctaaaga
    23401 atgggatgta gagacagaag gtagagatat ctatgatgta gcacatgaag tggcagaaat
    23461 tgcattaatg gaatttggaa aaccttttgg gacattaaga tttataaaaa atgcaccaga
    23521 accaagacaa aaaatatgga aagaatatgc tatagagcca agagctatag atagagaaat
    23581 tgcaacaata atgcactcta ctcatatagg atgtactggt gatatagata gtttaataca
    23641 catgagtctt agaacttcta tggctgatgg ttggggtggt tctatgatag gtactcgtct
    23701 aagcgatatc ttatttggaa ctccagtgcc aagaagaaca gaggctaact tagcagtatt
    23761 agaagaaaat aaagttaata taatattaca tggacatgag ccagcattat cagaaatgat
    23821 agttttagca tcagaagaac cagacctagt agctttagct aaagaagttg gagctgatgg
    23881 aataaactta gcaggtatgt gttgtacagg taatgagatt acaatgagac atggtgtaaa
    23941 aatagcagga gacttccatc aacaagaact tgcaataata actggagcag ttgaagctgt
    24001 aatagttgat gttcaatgta tattccctgc attagctaga gttgcagatt gttaccatac
    24061 taaatttgta acaacttctc caaaagctaa gataacaggt tcaacttata ttgaatttag
    24121 agaagaacaa gcacttgatg atgctaaagc aatagttaaa gaagctattt taaactttaa
    24181 aaatagagat aaatcaaaag tacttatacc tgaattaaaa tcaggagcaa cagttgggta
    24241 tagtgtagaa gcagtagtaa atcaattaga cagagttgta aactctcata tagacccagc
    24301 aggaacagtt aagccattaa cagactgtct aaaagctgga gtattaagag gagcagctgg
    24361 tgtagttgga tgtaacaatg ctaaaggagt ttcaaatgaa gctcacgtaa caataatgaa
    24421 agaattaatc aaaaacgaca taatagtagt tactacagga tgtggagctt cagcagcagc
    24481 taagtttggt ttaatggaag ctgatgcggc tgaaaaatat gcaggtaaag gtcttgcaac
    24541 tgtctgtaaa ttagtaggaa tcccaccagt actacatatg ggttcttgtg ttgatataag
    24601 ccgtatacta gatttagttg gagcagcagc taattactta gatatggata tgtgtgacct
    24661 tccagttgta ggtatagctc cagagtggat gtcagaaaaa gcagttgcta taggatgcta
    24721 tgttgtagct tctggtatag acacttatct aggaataatg cctccaatag ctggttcttc
    24781 aagagcagta gatatattaa ctagcgaatt aaaagataaa gttggagcga catttactgt
    24841 aaatacaaat ccaaaagagt tagcagctac aataatagaa gatatagaga agaaacgtgt
    24901 tcactttgaa gcattagttg aagaaaaaat ggcggaaaaa gctgaagctt aagaaatagc
    24961 gaagttatag aataaacgtt tttataagaa gtttatggct gaataaagtt gaataacgta
    25021 aaatattaaa gtaaagaact taaaatataa tgaatatact gaataaataa aatataaaca
    25081 atattaaaga ataataaaac tatacatgct gctttgaaaa gctagtaggg taaatctaat
    25141 tggttcctgt aaggactagc tgtagtttat ttttagtgta taaaaataga gagtataaaa
    25201 aatatttaac tataaaatta actactaaaa agcaaatagt aataaaaggt ggtatggatt
    25261 atgaagatag caataacagg taaaggtgga gtaggtaaaa cgactttttc ttcaatgctc
    25321 tctaggatgt ttgctgaaga cggatacaga gttgttgctg ttgatgccga ccctgatgct
    25381 aatttagctt tagcactagg ttttccaaaa gaagtatatg aatcaatagt acctatatca
    25441 gaaatgaaaa aattagtttc agatagaaca gctgcttctg taggttcatt tggaaaaatg
    25501 tttaagatga atcctaaagt agacgatatc cctgaaaatt tctgtaaaga atacaatggt
    25561 gtaagattac ttacattggg aacagtagat tctggtggta caggatgtgt atgtccagag
    25621 catgttcttt tgaagaggct ctgctcacat ctaatactac aaaataaaga tgtagtggtt
    25681 atggatatgg aagcgggaat tgaacactta ggaagaggaa cagcccaagg tgtagatgct
    25741 tttatagtag ttgtagaacc aggagagaga agtctacaga cttatagaaa agttaagaaa
    25801 ctaggacatg atataggtgt aaataaagta tttgtagtgg gaaataaaat tagaaataag
    25861 gaagatgaag aatttataat ccaaaactta gaagatggag aatctttagg atttatttat
    25921 tataaccaag atgttattga ttctgataga gctaatcaat ctccatatga ttctagtgaa
    25981 acaacgaaag aacaaattaa ggcaataaaa gataaattaa tgtcacttaa agataaataa
    26041 aataaataga atttttgatt tgggatttta agttggttaa aggttagaca taggcaatag
    26101 ataggtaata agtaagtaat tagataaata actagctatt aagtttgaat attttaatag
    26161 cttagtagct agtttttaag taattttaca tgtataatta tcttataaaa tataattttt
    26221 acatattaat acaattttca caaaaattat attttaaatc tatttaggtt gtgggaggag
    26281 attcagttat gggatttaaa tctgacattg aaatagctca agaagctaag cctcaagata
    26341 ttagagaggt tgcaaaaaaa ttaggactag gtgaagatga tgtagaactt tatggtaaat
    26401 acaaagcaaa agttgactac aatctactaa aaagagaaac tggtaaaaaa gctaagttaa
    26461 tactaactac agctataaac ccaactccag caggtgaagg aaaaactact actactatag
    26521 gtgttgctga tgcatttgct aaattagata aaaatgtatt agttgcttta agagaaccat
    26581 ctctaggacc agtatttggt gttaaaggtg gagcagcagg tggaggatat gcacaagttg
    26641 ttcctatgga agatataaac ttacacttca caggagattt tcatgctata ggagctgcta
    26701 acaatctttt agctgctatg cttgataacc atattcacca aggaaatgca cttagaatag
    26761 accctaagaa aataacttgg agaagatgtg tagacatgaa cgatagacaa cttagaaata
    26821 tcgttgatgg tatgggtaaa aaaggtgatg gagcagttag acaagatgga ttcgatataa
    26881 ctgttgcttc tgaaataatg gcagcgttct gtttggcaag tgatatatct gatttaaaag
    26941 aaagattagg aaatataata gttggataca gttacgaagg tgaacctgta acagctagac
    27001 aattaaaagc taacggtgct atggctgcat tattaaaaga tgctttaaaa ccaaacctag
    27061 ttcaaactct agaaggaaca ccatcatttg tacatggtgg accattcgca aatatagctc
    27121 atggatgtaa ctctgttata gctacaagaa tggctatgca ctttgcagat tatgtaataa
    27181 ctgaggctgg tttcggtgct gaccttggag cagaaaaatt cttagatata aaatgtagaa
    27241 tggctaactt aaaaccagat gctgttataa tagttgctac tgtaagagca ttaaaataca
    27301 atggtggagt tgctaaagca gacttaaatg aagaaaacct agaagctctt gaaaaaggac
    27361 ttccaaactt attaaaacat gttgaaaaca taactcaagt atatggatta ccagcagttg
    27421 ttgcaattaa cagattccca cttgacactg aagctgaact taaacttgtt gaagacaagt
    27481 gtaaggcatt aggtgtaaat gttgctcttt ctgaagtatg ggcaaaaggt ggagaaggtg
    27541 gaattgcagt agctaaagaa gttttaagat tattggatga agaagaaaat aactttaaat
    27601 tctgctatga agatgattta tctataaaag acaagataaa tgctatagct actaagattt
    27661 atggagcaga tggtgtagat tatactccag aagctgataa ggaaatagct aacctagaaa
    27721 gacttggatt tactaaagtt ccagtatgta tggctaagac tcaatattct ttaactgatg
    27781 accaaactaa attaggtaga ccaacaggat ttagaataac tgtaagacaa gcaacaatct
    27841 cagcaggagc tggatttata gttgcactta ctggagaaat aatgaagatg ccaggattac
    27901 caaaagttcc agcagcagaa aaaatagatg ttgatgaaaa tggagtaata gctggattat
    27961 tctaaggaaa ttaatttata aataaagagt aggaaatatc tctaaaataa tttgagatat
    28021 tttcctacat ccttttaagg aggattatca tgaaaatagc agataaaact tgtgttgatt
    28081 ttgtagaagt actatcttct aaagaagcag taccaggtgg cggaggagct gctgcactag
    28141 taggtgcaat aggtatggct ctaggcagta tggtatgtaa tcttacaata gggaagaaga
    28201 agtatgctga gtatgaagaa agtgtaaaag agatactaag taaggcagga aagttagaaa
    28261 aagatttatt aaaaatgata gatgatgatg cagaatgttt cttaccatta tcaaaagctt
    28321 acgggcttcc taaagaaacc gaagaagaaa aaagaataaa agcagaaaca atggaaaaag
    28381 cattaaaagt tgcttgtgaa gtaccattaa acatagtaag agtttgctat gaagctatta
    28441 aattacatga agatttagtt gataaaggct caagacttgc tataagtgat gttggtgtag
    28501 gagttcagtg tttaagagct gctatacttg gaggacaatt aaatgtagtt ataaatataa
    28561 attctataca agacaaggaa tatgttgata aagtaaaaac agaagtagat aagttagttg
    28621 aagatggtgt aaaaatttgt gatgaagttt ataccaaagt tgaaaaagct cttggaaaat
    28681 aatttttaaa tgacgaaagt agatactatg ttattaatat atggtatata gaataaatta
    28741 atttaagttt gcttgtaggg gagttgtgaa tgtatggaag gaatgtcaac taaaggacaa
    28801 attataaaag gaaaacctgt agctgataaa attagtgagg aattaataaa agaagtcgat
    28861 ttactagtta aagaaggtat aaatccgaaa ctaacaatag ttagagttgg ggcaagaagt
    28921 gatgatttat cttatgaaag aggagcatta aagagatgtc aaaacattgg tataacaaca
    28981 gaagtgttag agttagctga ggatataaca caagatgaat atattgatgt attaaagaga
    29041 gttaatgatg acaaaaatgt taatggtata ttatgtttta gacctcttcc aaagcactta
    29101 aatgaagaag ttataaaata tgttattgca ccagaaaaag atgtagactg ttttagccca
    29161 ataaactctg ctaaggtaat ggagggagat aaaagtggat ttccaccatg tactcctaca
    29221 gcagtagtgg agatattaaa acattataat gttgatttaa aaggaagtaa ggtaacagtt
    29281 cttggaaggt caatggtagt tgggaagcca gtatcaatgc ttttattaag cgaacatgca
    29341 actgttacaa tatgtcattc aaaaactaaa aatctatcaa gtgtagctgc agaggctgat
    29401 gtattaatag cagctattgg tagagctaag atggttgatg aaagctttgt taaggatggg
    29461 gcagtagtta tagacgttgg tataaatgtt gatgaagaag gaaatttatg tggagatgtt
    29521 gatacaaatg cagttttaaa caaagtatca atgataactc cagttccagc gggggttggt
    29581 tcagttacaa catctatact tgcaaaacat gtagttaagg cttgtaaatt acaaaacaat
    29641 aaatagatat atatgtggaa ggtttagggg ggaagtagat atgataattt ctgaaaataa
    29701 accattagaa gaagtgctag ggtacttgaa ggattttgac aagctggttt tagttggttg
    29761 taatcaatgt gcagcaactt gtaaaagtgg tggagaagaa gaagttttaa aaatgaagga
    29821 aactcttgaa ggtgaaggca aaaaagtctt aggatatgta atgcttgacc ctgcttgtaa
    29881 ccttttaaag tctaaaaagg atttaaaggc tctaaaagaa gagactaagg aagctgatgc
    29941 agttttatct ttagcatgtg gagatggtac acagacaata gttaagaatc taaaagataa
    30001 gccagtttat ccagccaaca atactttgtt tataggggaa gtacaaagag ttggagaata
    30061 tgaagaagcc tgtaaggctt gtggagactg tgaacttggt tggacaggtg ggatatgtcc
    30121 agtaactatg tgtgctaaag gtcttatgaa tggggcttgt ggtggagcta aaaatggtaa
    30181 gtgtgaagta aacgcagaga atgactgtgc ttggataaag atatatgaaa gattagaagc
    30241 tataggacaa ttagataact tagtagaaat aagaccacca aaagactatt ctaagcaaaa
    30301 taatccaaga agtttaagtg caaagaaaaa gaaagaagca gcagcaaatt cataaaagtt
    30361 ttttttagaa ggttaaaagg gggattagag atgagcttat taagagaaac attagaaagt
    30421 ggaaaatttg cagttactac tgaaatggct cctccaaaag ggactgacct ttcacattta
    30481 atagaatgtg caaagccgtt agttggaaga gttcatgcag caaatgtaac agattttcaa
    30541 tcggcagtta tgagagcaac ttctcttgct acatgtaaat tattaaaaga tgctggatta
    30601 gagccagtta ttcaaataac agggagagat agaaatagga tagctataca aggagaaatg
    30661 ttgtcagcag gtgtatttgg gataaacaat ctgttggcac taacaggaga ccatactagc
    30721 gtaggagacc atccacaagc taagggagtg tttgacttag attctgtggg gatacttcaa
    30781 actgctgaga ctttaatggc aggtacggat atggctggta ataaattaaa aggttctcca
    30841 gatttttatc taggagcatc agtaactcca gaatattctc caatagaagt tcaattatta
    30901 aaaatgaaaa agaaaataaa agcaggggct aaatttttcc aaacacaagc actttatgac
    30961 ataaatacaa tgagaaagtt tagagaatta acaagggata tggattgcaa ggtattagca
    31021 ggaatagtac ctttaaaatc accagggatg gctaaattta tgactgcaaa tgtaccagga
    31081 atatttgttc cagatgaaca aatcgaaaga ttgagagtag ctggaaaaga aaactgggta
    31141 agtgaaggaa taaaaatggc aggagaactt atcaaacaat taaaagaaga agatttatgt
    31201 gatggtgttc atataatggc aattggggca gaagagaata tacctgctat actggatgcc
    31261 gcaggtttat agtattgcaa gattgtagat tatattaggt ttgggggaat taaggatgaa
    31321 gatagtagta gtaggtggtg gaccaggagg atatgtagca gctataaaag cttctatgct
    31381 tggtgcagat gtaacagtta ttgaaaaaag aagagttgga ggaacttgct taaacgcagg
    31441 atgtatacca actaaagcac ttcttgcttc ttcaggagta ttgaatactg taaaagaagc
    31501 aaaggatttt ggtatagaaa tagatggtac agttaagcca aatttcactg ccataatgga
    31561 aagaaaaaac aaagttgtaa accaattaat aagtggtata gagttcttat ttgaaaaaag
    31621 aggagtaaac ttagttaatg gttttggaaa gttaattgat aaaaacacta tagaagtaac
    31681 taaagatgat ggaacagtag aaactataaa agcagataag ataatactag caaatggttc
    31741 tgttccagtt gtaccaagaa tgttcccata tgatggaaaa gttgtaataa ctagtgatga
    31801 agttcttgga cttgaagaga tacctgaatc tatgttaata gtaggtggtg gagttatagg
    31861 atgtgagata gggcagttct ttagagcctt aggaacagaa gtaactatag ttgagatggt
    31921 tgaccaaata ctattaaatg aagataaaga tgtagctaaa caactactta gacaatttaa
    31981 gaaagataaa attaaggtta tcacaggtat tggagtacaa acttgtgaag tagttgatgg
    32041 taaggctgtt gcaactcttt ctaatggaaa ggttatagaa gcacaatatg cattagtatg
    32101 tgttggtaga agacctaacc ttgataattc tggagtagaa gatataggaa ttgaaatgga
    32161 aagaggaaaa gtagtagtta atgaacatct tgaaactaat gtagaaggta tatacgcaat
    32221 aggtgatata atagatactc ctttcctagc acatgttgct tctaaagaag gtatcgtagc
    32281 agttgaaaat gctttaggta agactaaagt agtagattat agagcaattc caagatgtgt
    32341 ttatactgaa ccagaagttg ctggtgttgg taaaactgaa aagcaacttg aagctgaagg
    32401 tgtagaatac aatgtaggtc aatttgattt tagaggtctt ggaaaagcac aggctatagg
    32461 acatttccaa ggatttgtaa aagttatagc tgataaagaa actgataaga taataggtgc
    32521 agcagtagta ggacctcatg ctacagattt attgacagag ttgtcacttg ctgttcatct
    32581 aggattaaca gtagaacaag taggggatgc aatacatcca catccaagtt tatctgaagg
    32641 actaatggaa gcgcttcatg atgtacatgg ggaatgtgtt cattctgtac ctaaattata
    32701 atagacagac agagtacata aggctctgtg gctagattta agggggaagt cttaaaatgg
    32761 gatacaatat agctgttgca ggaaaaggtg gaactggtaa aacaagtctc acagggcttt
    32821 tgattgatta tttggttaag gacaaaaagg gaccagtatt agttgtagat gctgatgcca
    32881 atgctaacat aaatgaagta ttgggtatcg aagttgaggc aacaatagga gaaataagag
    32941 aagaagtaaa tcaaagagaa aagttaggca atgcattccc tggtggtatg acaaaggcac
    33001 aatatcttca atttagatta aattctataa ttgaagaagg cgaaggatat gacttattag
    33061 taatgggtag gtcagaaggt gaaggatgtt actgttttgt aaatggaata cttagagaac
    33121 aagtaaacaa aatatctggt cattacaaat acttagtcat ggacaacgaa gctggtatgg
    33181 aacatctaag tagaaaagtc actagacatg ttgatacact tttattggtt agtgattgct
    33241 caagacgtag catacaagct gttgctagaa taagagattt agctgaggaa ctaaagttaa
    33301 gtgttggaag aatacttcta attgtaaaca aagttccaaa tggggttatg aatgatggtg
    33361 tcaaagaaga aattgaaaag cataacctag agttaatcgg tgtcgtacct atggatgaat
    33421 tgatatatga atatgattct acaggtattc ctttagttaa cttacctgaa gattcaaaat
    33481 ctaaagtggc tatgaaagaa atttttgcta aattagaatt aaaataggtt taagggggaa
    33541 aaaaatatga catttaaaat gtctactcaa aaatattctg gaaaaatatc agaagttgaa
    33601 gtaggaatag gggaaaaagc aattaaatta ggtggggaaa atgtattacc tttttatagt
    33661 tttgatggag aagtaggtaa tcctccaaaa ataggtatac aaatatcaga cgtttatcct
    33721 gaaagctgga ctgattcata taaggagtta tacaaagatg tagctaaatg tccagtagaa
    33781 tgggctaaat atgttgaagc taacacacaa gcagatttta tttgtttaaa atttgatggt
    33841 tctgacccaa atggattaga taagtcagtt gatgaatgtg ctgatgtagc taaggcagta
    33901 attgaagcaa taaaattacc tctagttgta gctggttcag gaaatcatga aaaagatggt
    33961 aaattgtttg aaaaattagc tcaaacattg gatggacata actgcttatt tatgtcagca
    34021 gtagaagata actataaggg cgtaggagca tcagctggta tggcttattc acataaagta
    34081 ggggctgaat cttctgttga tataaaccta gctaaacaat taaacgtatt gttaactcaa
    34141 ttaggtgtta aaggtgaaaa tatagttatg aatgttggat gttcagcagt tggttatgga
    34201 tatgagtatg ttgcatctac aatggataga attagacttg cagcatttgg tcaaaatgat
    34261 aagacattac aaatgcctat cataacacca gtagcttttg aagtaggtca tgttaaagaa
    34321 gctatagctc caatagaaga tgagccagat tggggttgtc cagaagaaag aactatagca
    34381 atggaagttt caactgcagc aagtgtttta gtaggtggtt caaacgcagt tatacttcgt
    34441 catccaaaat caatagaaac tataaaagaa ttggttaacg cattagctta attaaattgt
    34501 taaggttagg gggaaaaaat aatggcatta aaagctttag atatatttaa attaacacca
    34561 aagaaaaact gtaaggattg tggattccca acttgtatgg ctttctctat gaaggttgct
    34621 tcaggagctg tagaagtagg taaatgccca catatgtctg atgacgctat agcaaaatta
    34681 tcagaggcta ctgcaccttt aatgaaagct ttaaaagttg gtgctggtgc atctgagtat
    34741 gaactaggtg gagaaacagt attatttaga catgaaaaaa cattagtaag tagaaataga
    34801 tatgcagttt cattctgtac ttgtatgagt gatgaagcag tagattctaa aatagctaac
    34861 atgaaaaaag ttgactatgt aagaattggt gaacaaatga aagttgaaat ggctgtttta
    34921 gagtattgtg gagataaaga tgcgtattta aaattaatag ataaaataaa aggcagtgga
    34981 ttagaagtag cttatatttt agcttgtgat gatgcacaag tagttaaaga agctgttgaa
    35041 gtattaaaag atgctagacc aatggtgtat ggagcaacta aagagaacta caaagatatg
    35101 atagaagtag ttaaaggagc aagtttacca ctaggtgtaa aagccggtag cctagaagaa
    35161 ttatatgaaa cagttgagtt aattcaagct gctggatata aagaattagt attagatgta
    35221 acaggagaaa acataaaaga tacttacact aatgctatac aagttagaag aatagcttta
    35281 aaagagcaag atagaacatt tggatatcct tcaatagtat ttgcaaatag attatctaat
    35341 tcaaacccta tgatggaagt tgctttatca tcaatattca ctataaaata cggttctata
    35401 atagtaatag atgatattag ttatgctaag gcattaccat tatttgcact aagacaaaat
    35461 atatacactg acccacaaag accaatgaga gtcgaaccaa agatttatcc aatcaacaac
    35521 ccagatgaaa attctccagt attagttact gttgactttg cattgactta cttcatagtt
    35581 gctggggaca tagaaagatc aaaagttcca gtatggttag taataccaga tgcaggtgga
    35641 tattcagttc ttacatcttg ggctgctggt aaatttggtg gaaactcaat ttctgctttc
    35701 atcaaagaaa gtaaagtaga agaagtaact aattgtaaag accttatcat tccaggaaaa
    35761 gttgcagtac ttaaaggtga tatagaagat aacttaccag gatggaatgt agttatagga
    35821 ccagaagaat ctatggaatt acctaagttc ttaaaaggat accaagaaaa agcatgccaa
    35881 acaaactaat aaaatattaa ctaactatta atattaaatt taaaggggga cattataaat
    35941 ggaaaaattt atgattatag gtgaaagaat acactgtata tcaccttcaa taagaaaagc
    36001 attagcagaa agagacccag ctccaatctt aaaaagagca aaagaacaat tagaggcagg
    36061 agcacactat atagatttta atataggacc tgctgaaaga gatggcgaag aaataatgac
    36121 atggggaatc aaattacttc aatcagagtt caacaatgtt cctatagcat tagatacagc
    36181 taataaaaaa gctatcgaag ctggacttaa agtttacgat agaactaatg caaaaccaat
    36241 aataaactct gctgatgctg gttcaagatt tgatttaata gatatagcag ctgaatatga
    36301 agcaatggtt ataggtttat gtgcaaaaga aggtatccca agagataatg atgagcgtat
    36361 ggcttactgc caagaaatat tagaaaaagg cttaatgtta ggaatggagc caactgatat
    36421 actattcgac ccattatgct tagttataaa aggtatgcaa gaaaaacaag tagaagtttt
    36481 agaagctata aaaatgatga ctgagatggg acttttaact acaggaggat tatctaatgt
    36541 atctaatgga tgtcctaagc atgttagacc tgttttagat agtgcattct tagcaatggc
    36601 aatggccaat ggatttagtt cagctataat gaatccatgt gacccagaat taatgaaaac
    36661 tgtaaaatct tgtgacataa tcaacggggc atctttatat gcagactctt tcttagagct
    36721 aaatgaaggt ggatttgctt tctagggttt ttagggtata gttaataaaa aataggtgta
    36781 aatattaaag ggggaaatag aatgaatcta tataatataa tctttacagg gtcagaacaa
    36841 gctttaggtg cggctcaagc tatgctagct gaagctatag aaaaaaatgg aaaagaacat
    36901 aaagttgctt tccctgatac agcatattca ttaccttgta tatatgctgc aacaggacaa
    36961 aagatgaaca ctttagggga cttagaaggt gctttagaag tagtaaaatc tttaataaat
    37021 agaactcatt tactagaaca tgctttcaat gctggcttag ctacagcttt agctgcagaa
    37081 gtaattgaag cattaaaata ttcaactatg gatgctccat atagtgagcc atgtgcaggt
    37141 catataactg accctataat cagatcactt ggtgtaccac tagttacagg agatatacct
    37201 ggtgttgcag ttgttcttgg tgagtgtcca gatgctgaat cagcagcaaa agttataaaa
    37261 gattatcaat ctaaaggttt gctaactttc ttagttggta aagttataga ccaagctata
    37321 gaagctggag taaaaatggg tcttgaacta agagttatac ctctaggata tgatgtaact
    37381 tctgttattc acgttgtatc tgttgcagta agagcagcat taatattcgg aggattaact
    37441 cctggtgatt taaacggatt attagagtac acagctaata gagttcctgc atttgttaat
    37501 gcatttggac cattaagtga attagttgta tctgcaggtg ctggagcaat agctttagga
    37561 ttcccagtta taactgacca aacagttctt gaagttccaa tgaacctatt aactcaaaaa
    37621 gattacgata agatagtagc tacttcatta gaagctagag gaataaaaat aaaagttact
    37681 gaaataccta tcccagtttc atttgcggca gcatttgaag gtgagagaat tagaaagagc
    37741 gatatgtttg ctgagtttgg tggaaacaga acagaagcat gggagcttgt tgttaagaaa
    37801 gaagcaacag aagttgaaga ccataagata gaaataatag gaccaaatat agatgaagtt
    37861 gatgcagatg gtgtattaag attaccactt gctgtaatag ttaaaatagc tggtaaaaat
    37921 atgcaagaag atttcgagcc agttcttgaa agacgtttcc actacttctt aaactatata
    37981 gaaggtgtaa tgcacgttgg acaaagagat atggcttggg taagaatctc taaagatgca
    38041 tttgataaag gctttagact tgagcatata ggagaagttt tatatgctaa gatgttagat
    38101 gaatttgaat cagttgttga taagtgtgaa ataactataa ttacagatgc tgaaaaagtt
    38161 tctgaattaa aaggtgaagc aatagctaag tacaatgcta gagatgaaag attggcttca
    38221 ttagttgatg aaagtgttga tactttctat tcttgtaact tatgtcaatc atttgcacca
    38281 gctcacgttt gtgttgttac tcctgaaaga cttggtcttt gtggagcagt tagctggtta
    38341 gatgctaagg ctactaaaga attagaccca acaggtcctt gtcaaccaat agaaaaaggc
    38401 gagtgcttag atgatagaac gggtgtatgg aactcagtaa atgaaactgt aaaccaaata
    38461 tctcaaggtg cagttgaatc tgttacacta tactctatat tagaagaccc aatgacttct
    38521 tgtggatgct tcgaatgtat ctgtggtata atgccagaag caaatggatt tgttgtagtt
    38581 aacagagaat ttgcaagtgt tactccagtt ggtatgactt tcggagaact tgcttctatg
    38641 acaggtggag gagttcaaac tccaggattt atgggacacg gaagacattt catatcttct
    38701 aaaaaattcg cttatgcaga aggtggacca gaaagaatag tttggatgcc aaaagaatta
    38761 aaagattatg tagctgataa attaaatgct acagttaaag aaatgactgg aatagaaaac
    38821 ttctgtgata tggtttgtga tgaaactata gcagacgatt ctgaaggagt attagctttc
    38881 ttagaagaaa aaggtcatcc agcattagct atggaaagtg taatgtaatt gatggaaaat
    38941 ttaaaataat atgatataat attaatatga tttaagtaat ttaatcaata atataatatt
    39001 gggggtctat cgaaatgaaa ttattaccag aattaaaata ctctaaggat catgagtggg
    39061 taaaagtaat tgatggagat gttgtatata taggtataac agactatgct caagatcaat
    39121 tgggagaaat attgtttgtt gaaacaccag aagtagaaga tactgtaact aagggagtag
    39181 attttggagt agttgagtct tctaaagtag cttctgattt aatatctcct gttaatggtg
    39241 aggtattgga agttaatgaa aaattagaag atgagccaga atgtataaat gaagacccat
    39301 atgaaaactg gatattaaaa gtaaaactag ctgatgtggc tgaacttgat acgttattaa
    39361 gtgataaaga atacgaggct ggattagaat aattaaagat taggatatta ttataattgg
    39421 ggaaagtata gtaaaatttg agtgcacgca aatttagcta tactttcctt ttatcatata
    39481 cagaacaaat tgggagggat aacatgataa aagtgagttt tacaccaaac aataaagagg
    39541 tttattgtaa tgagggggat atattactag aggttgcaag aaatgcagat atattcatag
    39601 atgctccctg taatggaaac gtgtcttgtg gtaagtgtaa agtaaaatta ttgaatggaa
    39661 aagttgatac agaaaaaaca agacatataa cagatgatga gtgggagcaa ggttatatac
    39721 tagcttgttg tacaaaggta atatcagata tagaaattga agttccttct aaagtatcat
    39781 cttctatgca tggtatgaag atagaaggta gtaataaaaa agaggataga gaaatatttg
    39841 aaagagctaa aaaaataatt gaagaacata accttcaatt taaaacaaat ataaaaaaga
    39901 aatatataga aatggaagaa ccaaatttag atgataatat aagcgacgta gatagattgg
    39961 aaagatatgt tagaaataac ttagggtaca atgaaataga ttttagattg gatatactta
    40021 gaaagatgcc aaccatattt agaaagagtg attttaaggt tacaataaca tatgttcaaa
    40081 aacaaaagaa acttacaatc ataaatatag aagaaggaaa taaagaaaat tccttatatg
    40141 gagttgcaat agatattggt acaacttcag tagttgtttg cttagtagac ctatactcaa
    40201 aagaggtagt agataaagca tcttctggaa atgcacagat aaaatacgga gcagatgtta
    40261 taaatagaat tatatattca actaagaaaa atggattaga gacacttcac aaagccatag
    40321 ttgaggaaac tataaatcca ctgctaaaaa caatatatga gagaaatgga atagataagg
    40381 aggatgtagt tacattagtg gctgctggga atacaactat gacaagttta ttcttgggtg
    40441 tatatacaga cttcttaaga caagagcctt acataccacc atttttaaaa tctccaaaac
    40501 ttatgggaga aaatgttggt ctttttgtaa atgacagtgc atatgtgtac ttagctccat
    40561 ctgttgcaag ttatgtagga ggagatataa cagcaggtgt attatcagca ggtatatggt
    40621 caagtgaaga aaatgtttta tttatagatt taggaactaa tggagagata gtatttggaa
    40681 ataaagatta tatgatgagt tgtgcatgtt cagcaggtcc tgcctttgaa ggtggaggta
    40741 taagctgtgg aatgagggca tcagcaggag caatagagaa agtaattatt gataaagaaa
    40801 ctttagagcc aacattaaaa attatagatg aatgtgcacc agttggtata tgtggttctg
    40861 gtataattga tttaatctgt caaatgatta ctaaaggtgt aatagataga agaggtaaaa
    40921 tatacaggga tttagataac aagagagtta gatttaatga gcatgagata ggagagtatg
    40981 tattagcatt taaagaagaa tttgatttag aaaatgatat agtagtcaat gaagttgaca
    41041 tagataattt cattagagct aaaggagcta tatattcagg tgcatacact cttgtagaca
    41101 gtttaggtat ggattttagt atattagata gggtttatat agcaggtggt ataggaaata
    41161 acctagacat agaaaactca ataattatag gtttacttcc tgatattgat agagaaaaat
    41221 ttacttatat aggaaatagt tcacttgttg gttcttattt agctctcata agtaaagatg
    41281 caaaaaataa acttgaagaa ataggtaatc aaataactta tgttgaactt agtgtatatc
    41341 caagctatat ggatgaattt atttctgcat gtttcttacc acatacgaat atagaacagt
    41401 ttccaacagc aaagaaatta ttagaagagt aaaatgaact taagaaggaa taaactatga
    41461 ataaaaatct atctgaaaaa gtgaaagtag catttgatat taaattaaaa aattttggaa
    41521 ataaaataga gtttgcttat cctaatcaga cactagctct tagtaccaca aacaataaat
    41581 gtagtttaaa atgtgctcat tgcaatggtc actatttaaa caatatggta ccaatagagg
    41641 attatgagga aaaagtacaa tcaagaaata taactagttt tttattaagt ggtggatgta
    41701 gctatgatgg tgatgtccca atgagtactc atattcagac tattaaaaga ttaaaggagc
    41761 aaggttacag attgaatgct catttaggac ttatggataa agagagcatt atagaattgt
    41821 gtaagtattt agatatagtt tcttttgatt tagtatttga taaagaaaca ataagagaag
    41881 tttataagat ggaaaagagc aaagatgatt atatagaagt ttataataca ataagagaaa
    41941 atacagaagt agcaccacat atatgtattg gtttaaaagg aggacagata aaaggtgaat
    42001 atgaaattat cgaataccta cagaaaaatc ctcctaataa acttacattt ataatcctta
    42061 ttccaacaaa aggaactgag tatgaaaatg tagaacctcc tgaattagaa agggtagcag
    42121 atattttatg tgaagctaga attaatttac catatactga aattaatcta gggtgtatga
    42181 gaccaagagg agtgtataga aaagagctag accagttatc tataatgtgt ggagtcaata
    42241 aaatagtatt accatcaagg tctgccaaga ataaagctat agaaatgaat atgacaataa
    42301 ctgaatgtaa ggagtgttgc gttttatgat tagactatca gttggaacag caatagaact
    42361 tggaatatta aacaaaaaaa gcgatatacc tcctactaca gcatatataa tgattggaga
    42421 aaaatgtata aataaatgta gtttttgctc ccaatcaata gaaagtagta ctagaaaaga
    42481 taaattgtcc agagtagttt ggccagagtt ttcaaaagag gaaatattag atgcgttaaa
    42541 agcttataaa ggaaaaaata taaagagaat atgtattcaa tcaatggcaa gtgaagaagc
    42601 acacaactct gttttagatt ttataaacta tataagtggc aagatagaca tgccaatttc
    42661 actatctgca aaattagaaa atgatgaaca gataaataag tttttttcag caggagtaga
    42721 taaaatagga atagcaatag atgcagcaaa taaagaacta tatgaaaaaa taaaaggcaa
    42781 taattataat gaaaagttaa aatttataac tgaaatgtca aaatcatatc ccaataaaat
    42841 aagtacacat ataatagttg gtatgggtga aagtcatgaa gatatataca atttatatac
    42901 ttatttaaag ggaaatgaca taacgattag tttatttgca tttactccag ttagaggaac
    42961 taaaatggaa aagataaatc aaccaaatat agaaagctat agaagggtac agttaatgtc
    43021 ttatatgata aataaaggtt attcaaaaga gtattttacg tttaaaaatg gatacttaga
    43081 tagcataaag cttgacaatg atattgtaaa agacataaac aaaggttatc cttttgaaat
    43141 aagaggttgt aaggattgta atagaccata ctataatgaa agaccaggta gtactatata
    43201 taactattca agacctttaa atcaaagtga gatagattta gcaataagag aaataaatct
    43261 atagaggatt tctaggatat atttatacta aaaatggggg cgtaataatc atgaatcagt
    43321 ggagagttat acataataaa tcatatgaag gagcaatgaa tatggcaatt gatgaagcta
    43381 tatttactgc atataagaag ggacataata agccaactct tagattttat acatgggaac
    43441 cagcttgtct gagtatagga tattttcaga aattggaaga tgagatagat ttggacaagt
    43501 gtagatgtat gaatatagac tatactagaa gaattacagg tggaagggct gtattacatg
    43561 ataatgagct aacttatagt ataattatag gagaagataa tcctttaatt gataagagca
    43621 tcaacctgtc ttatagatat ataagtgaag gtctagttaa aggactgaat ttaagtggta
    43681 tagaaacaga taatttgaat agaggcgaga gaataagtag ggaaaattta tcagctgcgt
    43741 gtttcaatgc acatgcatca tatgaagtta ccattaataa taagaaagta attggaagtg
    43801 ctcaaagcag aaaagatggt gttttattac aacatggttc aataatactg gattttgatg
    43861 tagaaaaatt gtttaaatta ataaaaacga agacaccaga actgaaagaa agggctatga
    43921 aatttacagc taaaaaagca agtggaatag aaaatgaaat tggcagaaaa atagacatag
    43981 atattctaca aaaaaacata gtaaagggat tagctgaaca atttaatgtt gagtttgtgg
    44041 agggtgattt aactgattac gagaagcaat tagctaaaga actatatgaa aaatacaaga
    44101 atgaagagta taataaaaag cgttaacttt aattgacttt atataaatta aagtgctata
    44161 cttaaggtat aataatatac aaaaactgaa atcatgaagg tttctttggt gtattgaaat
    44221 acctaaggaa atcttttttt gatttttaat aaaaatcata ttaggaggag atttatatgt
    44281 gtgaatcatc agctttcatt tgtaaaagta ataatgagtt agaaaaggtt atggaaaatg
    44341 tggttaatat agacccttgt gatggaaaga tttatttaac ggatttatta ggagagcaaa
    44401 agataataga tgggataatt aaagaaataa gattgatgga ccataagata ataatacaag
    44461 aaaattaatt aataggggaa tttcatatga taatagcagt gatagatgga atgggtggag
    44521 gtattggagc ccagatagtt tcttctttga gagaagagtt acctacatat gtagaaattt
    44581 atgcactagg gactaattct atagcaacta gttctatgat gaaggctcat gctaataaag
    44641 gagctacagg ggaaaatgct atagtagtat cagctaaaaa agcaaatata atagttgcac
    44701 ctatttctgt aataatacct aattctatga tgggagaagt tacttgtaat ataagtgaag
    44761 ctattgcaga tagtgaggca cttaagatac ttttacctat tatgccagaa aatgtggagt
    44821 tagttggatt agaaggtaaa ccattagcac tacttgtaaa agattctgta aatcttataa
    44881 aaaaagagtt taatataaaa taacaggggg aataactaat gatttttgat agagagattg
    44941 taagatatca tcatggacat catgaccatg accattgcca cgagcatact catggagata
    45001 tatgtcatga acatccacat gaccatgctc atgaccatga ccacgaacat agtcatgagg
    45061 aatcatcaga gtctaaggat gaaaaaactt taaaaatact tttggtacat tggataaatc
    45121 ataatgaaac tcatgaagaa ggatttagag agtgggttga aaaggctaga gctattggaa
    45181 aagaagaaac agcaaagagt attgaaaagg ctatagagta tatggaagaa gctaataaaa
    45241 tgttgttaga ggctaaaaaa catatgtaaa tataattaat cgcttatacg tttgatataa
    45301 gcgattttta tgttttttga tgcttaatta ttaaatttct tatctaatgg attgtctcaa
    45361 aatagatata agcctctctt tcattgttga aatgataaaa atatacttta aaggctgttt
    45421 aaaattgctc caagattaga tataataaga attagtataa ttaaaaatat tgttttgaag
    45481 ttaaaaaatt tatgtattta tataagattt tttctttaaa aaaggagtga attatttatg
    45541 aaagatggtc atatacattc accttattgt cctcatggga gtaaggatga ttttgaaaaa
    45601 tacgtacaaa gagcaatgga tattggaata acagaaatga cctttacgga acattttcca
    45661 tatgcaaatg gatttagaga ccctgctcct gaaaatgata gttgtatgag tattgaagat
    45721 ttgccaaagt attttaatga tgtcaagaag ttgaaagaaa agtatgaggg taaaatcaag
    45781 ataaatgttg ggtcagaagt ggattttata gaaggatacg aagaagggat aaaggcgaat
    45841 ttaaataaat atggagaaga attagaggat tctcttttat cagtacatat aattaagatt
    45901 gatgatgatt attattgtgt agattacagt atagaagaat ttcaaaattt aatcgacaag
    45961 ctaggtagta ttgaagctgt ttataataag tattatgaaa cactgataaa agctgtaaat
    46021 tcagatttag gtatacataa accaaaaaga ataggtcatt taaatttagt tagaaagttt
    46081 aatcaggtat ttccatacga ttataaagga aataccattc ttgaagattt aataaagtta
    46141 attaaagaaa aaggttatga acttgattac aatgtttctg gaaatagaaa agagtactgc
    46201 aaagagcctt atatagatgg atacttatta gagttggtaa aaaaatacga tattccatta
    46261 gttttaggct ctgattctca ctgtgcagag gaaataaata aatacgatat tgtttagata
    46321 tatttgcata aaagactgta gataagtttg aataaaataa atttatctac agtcttttgt
    46381 aaatttatat gattaaaaat agtaatagaa cttaaataaa ataataatga gttctaagta
    46441 aaataacaat agaatctaag taaaataata ataataaaat tcaatagaat aataggattt
    46501 agaattaatc tatcttattt atataaacat tcttatataa gattgtagat aagcttgtat
    46561 ttacacaaat ctatagatat tctctattat attgacttag taattataag tactattttg
    46621 catttaaagt tattatttca taagtttatc gttttccatt attacagggt caggcaattc
    46681 aatttcactt tctgacatct tcaatctatt aaacatataa ttttttacat ctttcttgtt
    46741 tttaaattta gtaacttgat aaggtgatgt agggccgtat ttttctacaa atagaatgcc
    46801 atttttagtt ttaatacata tgcctgtatg acctataaat acgtttttag tttctggata
    46861 acgaagaaat ccatttataa tagatatatt tttattattt ttaaaagata tttttctttt
    46921 tttccactca ttttttattt gttctgcaat tttagatata tcacttgtat ctttagctgg
    46981 tattgcagaa aagaagttga taaatttttc tacatctttg gtgctaaatt tagcatcttt
    47041 attattcatt atagtgtcca agtcgacatt taaatcaata gagtctccag taaatttatt
    47101 atttgaattt ataaaatctt taaaaagtct aaaagcagtt attctacaat ttacatccat
    47161 ataatcaggg aattttttca tccaattatc ttgcaatttt tctaggttat atggaacttg
    47221 ttttgcattg attgaagaat atccagattt agatatattt atattatttt gaagtatttt
    47281 aacttgcaat ttattataat tgttgactgc tttaataaat gtatctatgt ctttttcatt
    47341 aattttattt tcttttagaa tttcctctac actattttga gttcttttat ctatcatatt
    47401 agaatatatc aatttattat tatatttaat atttgaatat gcaaatatcg taagtacact
    47461 tgatagtact aagacaagag ataatataat tattaatctt tttttcattt tgagttctcc
    47521 tttttaaatt tattgtgtcg acatatttat agtatatagt acctttaaat ttaccttcaa
    47581 tatgttttta attacaaaac tgttgtaaaa aatataacgt tatttaaaac ttttttttaa
    47641 tatgtaaaaa tatatactga tagggggtat ttgtttttag aatattcagt aaaatagttt
    47701 tgagatatta tatatatttt gtatgttaaa aataaagaaa ttattgttaa aacagataaa
    47761 gaccttaaat tttttatcgt aagcttttaa gtaaataaga cgtattgaac taattaaaaa
    47821 tttttatttt gtaaaaatga gtatttattt atatggataa atttgatttt aaatctatca
    47881 atatagataa aatctcatta tttaacttca actattcctc aaaaaagtaa cttttaagga
    47941 atagttgaaa caaaaagttt ggttacataa tagtaatttt agttacaaga atgaaactgt
    48001 aatacttagg attttcttta tataatttca ttgagaacat ttaacttagg aggtaagata
    48061 tgaaagtaaa aaaatttaaa agtggtatag taatggcatt aacagtaatg gtaattggag
    48121 catcattgac aaatgtatca gctatggaat taaataagag taaggagttt gaaactaaat
    48181 acaatgaaat gaagagggat tttcaagagg aatatggaaa agaagacaaa tttaatataa
    48241 cattggatga tgaatttaca aaagaagaag taaatggagc taaagggatt ataaagacaa
    48301 ctaataaagt gaataatgag gttgtagtat taaattattt tgatgaaatg aaatctggga
    48361 ttgaatttga gttgaagcca aaagcagaaa aaaatgtaat tttgagagag gaatttcaac
    48421 aaggttatgg aaaggaagat aaattcaaag ttgtgttaga tgatgaattt acaaaagaag
    48481 aggtaaatgg agctaaggga attataaaga ctacagataa agaaacaggt gaggttatcg
    48541 tatataatta ctttgatgag cttgaaaaat aatgtgtaaa gattactttg attgaatgca
    48601 aaggtaattg ttttgagaat atgaaatgac tgaataaaaa acgattgtat caaaaacaaa
    48661 taataattga atgtaagtat aattgtatca aaaatataaa ataaattaaa agaaaaagat
    48721 tatactgaag gaaaaagatt tgaaataggg gtgaacttta catattatag ttcaccctta
    48781 tacaaaaata taaaatataa tttattatag gaaaatttaa aaaaatcaga ttatttaatt
    48841 tatactgata tgttgtagga ttttacaaac aaactgttat ataacttttt ttatctccaa
    48901 tcttgatttt aatatatcta agaatttata acaatcttct ggatatattt ctcccatatt
    48961 tgcaacttgg aatatgttag catctaggaa tttgcctttt cctggatata caacatagcc
    49021 actttccctt tctagcccta atataaactc atctacattg atttctttag gtagaaatac
    49081 agatgttact gtattagaca tatacttatc tggaagtaaa aatgttagac ccaattcttc
    49141 catgccattc cttaaaatag cagaacattc tttgtatctt tctattttac tgtcatcttc
    49201 caaaaactca gttaaagctt cattaagggc aaatattaaa gtaacattag gtgtatttgg
    49261 tgtttgagaa gatgatttag caactttata gtgtttataa agattaagat acacattctt
    49321 acattgattt tctttaatat cttgtaaaat actctcttta gcacaaaggt atgcagaacc
    49381 tggaaatgct ccaagagctt taccaccaac acctgttatt atatctatat taaactcttc
    49441 cacatcaata tattcacctg ctgatgcact tattgcatct acaaaaaata ttttgttata
    49501 cttcttagca agttttccta gttcaggaac cggatttatc attcctgaac tagtttcatg
    49561 gaacaccata gcaattactt ttatatcaga atgttcaatt atatattttt ctaaaatgtt
    49621 taggtctggg tattctgccc attcaaaatt aggcttatat gtttttacat tataagtaga
    49681 taatatttct tctagtcttt ctccaaaaac accattacta actagcagaa ctgcatcttc
    49741 tttatcaaag atagaagata gtacacattc atttacagat gttccagagc cagatacaat
    49801 taatgagtag taattagaag ttgcattata tagtttattg attttttgtt gtgtatcttt
    49861 gaataaatcc ataaactcat ttcctctatg gcatatatca tagtgaagaa gtgaatttct
    49921 gactttatct gtaaccatta ctggtccagg actgaataga tatgtttttt tcattgtaaa
    49981 gcctccttaa aaagttaaat ttaaattttt gaatgactga ttatgtgtaa atattagaat
    50041 attatgtgtt attttaacta gattatagaa taaaataata aatattgcaa taatatttta
    50101 ataaaaatac ttttttaatc atgttaatta aaaataacaa aaaatattgt aatgaatatt
    50161 gcataaatcc acatgatgat ataaaatata aataacttga atagattata tattcaaaaa
    50221 ataaaaaaga atttattaat tctgaaaata aagggggaca tttaaagtga aatatgtatt
    50281 agcaattgac caaggaacaa caggaacaag agcagtattg ataaacgaaa aatcagagtt
    50341 tgtttttagc gattatatgg aacatactca aatatatcca caatctggat atgtcgaaca
    50401 tgaccctata gaaatttgga ataatacaaa aactgtgagt aataatgtat tacaacaggc
    50461 ttttgaaaat ggaatcaatg aaagcgatat aaaaggaatt ggtatagata atcaaggtga
    50521 aacagtaatg ttatgggata aaaatacagg taaaccactt tacaatgcta ttgtatggca
    50581 gtgcaggaga acttatgatt atgtggaaaa tttaaagaat ataccaggtt tagaaaataa
    50641 gataatagat aagactgggt taattataga cccatatttc tcaggcacaa aaattaaatg
    50701 ggtaatagat aatgtaaaag gtgtaaaaga aaaaattaaa aatggagaag tacttgcagg
    50761 aacattagat agttggttaa tatggaaaat gacaggagga aaatcttttt taactgatgt
    50821 atctacagca gcaagaacaa tgctttttaa tataagagat atggattggg ataaagagtt
    50881 gcttgacatt ataggagtgc ctagaagtat tttagcagat ataatgccta caagtggtga
    50941 ttttggaact acagataagg aggcattttg tggggtttct ataaaaatta ctgcttcaat
    51001 ggtagaccaa ccagcagctt tatttggcaa tggatgtttt gaaccaggaa tggttaaaaa
    51061 tacttatggt acaggatgtt ttctatatat gaatataggt gaggaactaa atatagcagg
    51121 taatggcatt ttgacaactg ttgcttggaa aataggagat aaagttacat atgcttatga
    51181 tggtggagtg tatatagcag gtgctgcaat acaatggctt agagatggaa ttggagttat
    51241 aaaaaattat tcagaaactg atgacatggc aaattccata tcaagtactg gaggtgtata
    51301 ttttgtacca gcatttgcag gtatagcagc accttattgg gaccaatatg ctagaggtac
    51361 aatggttggg ataacaggaa gtactaaaaa agagcatata gtaagagcga ctcttgagtc
    51421 tgttgcactt caagtcaagg atgttgttga ttctatgaac ttagcctcag ggaaaaaaat
    51481 aaaaatgttg agagtagatg gtggaattac taaaaataac tttacaatgc aatttcaatc
    51541 cgacatatta ggcataccaa ttgaaattgc agaaaatccc gagacaacag tacttggagt
    51601 aggatatatg gcaggtcttt cctgtggtgt ctggaacagt attgatgaaa ttagaagtga
    51661 atttacaata agcaaaaaat atattccaaa tatgactaat caaaaaagag aagaaatatt
    51721 acttggatgg aatcaagcag taaaaagagc tatgaattgg gaaaacgata ccaaaaaagt
    51781 gtgtgctaat taagttacaa tagagtattt tacatgtata ggaggaatta aaaatgccct
    51841 ttgataaaat tatattatac ataatggctg tgggagtgct tttaggagcg ttagatagaa
    51901 taattggaaa taaatttgga cttggagagc agtttgaaga agggtttaat tcaatgggtc
    51961 cattggcttt aggaatggtt ggtatagttt gtttagctcc agtaatttca gatgtactag
    52021 gtcctataat aataccaatt ttcaatctct gtggagctga cccatctatg tttgcaacta
    52081 ttttagcgaa tgatatggga gggtatccat tggctatgga acttgcacac aataaagagg
    52141 caggaatgct tgcaggattg gtcgtgtcat ccatgcttgg atgtacatta gtattttcaa
    52201 ttccagtagg actaggtctt atagaatatg aagacagacc attctttgca aaagggttac
    52261 tgataggcct gataacaata ccttttggag gtgttatagg aggattaata gcaggattta
    52321 acttatcaat ggtaattata aatatgatac cagtgataat attgtcagta atattggcag
    52381 taggtttaaa atttaattct acacttatga taaatgggtc attagttttt ggaaaattta
    52441 tatctatatt gataacgata ggtttgggag cagcagcatt tcaagaaata acaggtatag
    52501 tacttataaa aggcatgaca cctataagag aagggattca agtaattgga agtattgcaa
    52561 tagtgttatt aggtactttt ccaatattac atttattagt taaagttctt aataaaccac
    52621 ttacaatagt gggtggaaaa ttaggtatgg atgccactag tgcagcagga ttagttttta
    52681 ctttagccaa tagtattcca gtatataaaa tgatgaaaga tatgagtcca aaggggaaag
    52741 tagtaaatac tgcttggttg gtttgtgcta cagcagcttt gggagaccat ttaggattta
    52801 cagcaggagt agttccagag atgattacac ctgttgtaat tggaaaattg gttggaggag
    52861 tattggcaat tgcacttgcc atacttatga caaaagattt aactttagaa gaagaacaaa
    52921 gtattaaaat gaagaaagat gcagtgtaga ataaataata attaagtcaa atttaaacta
    52981 ttttaaagta ggagtttaaa taactaaaaa taaattaaaa agacagacaa ttaaaaaata
    53041 atcgaatatc caaaacttat aaattaaata aaatggcaat caaataacta aaaatgataa
    53101 gttaactgaa agtaattaca taattaaaat ataaagtata gtttagacat aaatggagct
    53161 aaataaataa ttatttggct ccttaatttt aatttattac atcaaggaac taaaaatcaa
    53221 tcatacaaac taattatcag ctatgactaa aggtattcct ttttgagaaa actctattat
    53281 tatattatgg tctatactag cagaggtaat aatagtatct atatgttcta taggagctac
    53341 tgatgcaaat gaatttatac caaacttagg aggttcgaca actactatag attttctaga
    53401 cctttcaatc attttttttc taacaagtgc ttcttctaag tgatagtcag agattccatt
    53461 ttcaagagtg atacctccag cacctaaaat agctttatca acattaaatt gttcaatagc
    53521 tgacagtgta agcggaccag aaaaagaacc ttcagtttct ctaagatagc caccaagcac
    53581 atatactttt atattagtat tcataagttc gtttgcaact aaaattgagt tggttattac
    53641 agttagattc tttttatctt tcaaattttt tgaaacttca agtacagtag ttccagtatc
    53701 cataaaaata gtatcatttg tatttataaa ctcactacat ttaatagcaa tctgtttttt
    53761 atcgtttgag tttatttttt ttcttttaac atagttaagt tctacgctac ttgctataac
    53821 tggtatagca ccaccataaa ctctttttaa aagaccgata ctctccatat gggctaaatc
    53881 tcttcgtgca gtttctattg atatatcaaa catttgaact atgtcattta ttttaattat
    53941 attatctgat ttgagaatac ttaaaatctt ctcgtatctt tcctgtggta acataaaata
    54001 tcctccttgg actagtatta ttttagtttt ggcataactt acaattaagt cagagtttag
    54061 gtatatttgt taatgtatgt atatttatca aataatatta taagtgttat gcaagataat
    54121 tttaccatat ttaaaactta catttaagca aaaaagtaaa aatagatgtt taataattca
    54181 aaataactca aattttataa aacaattgac taaaatatga ttttattata taatttatta
    54241 gtatagagat atggagaagt actcaagtgg ctcaagagga tcccctgcta agggattagg
    54301 ctgggtaacc ggtgcgaggg ttcgaatccc tccttctccg ccaattgtta aaggctattt
    54361 ttattaaaga tagtcttttt atgatgtcat aaatgattag atatgtataa ctaaagaaag
    54421 gagggaatag atgacaactt taattttttt catagtgggg atagcatctt tggtagttgc
    54481 ttttgtaatt gatggggggc atgttggagc gttatttgta ttttcatcag cactcgttgt
    54541 ttttggtgga actataggag ctgttggagc ttcgacgcca ttccctgtat ttaaaaagtc
    54601 tataaagata atgttattag cttttaaaaa taaaaagcct aataacatag aaaatataat
    54661 ctatttcaaa gaaattgcaa caaaggctag gaaagagggg cttcttagta ttgacaagga
    54721 aataagtgat aataatgaat tagacccttt tattaaaaaa gggcttgaac tgatggtaga
    54781 tggagtggat gcagttacta taagaagcat attggaatca cagatacaga taacatcaaa
    54841 acgacataaa gaaggaattg caatttttga ttcagcaggt ggatatgcac ctacaatggg
    54901 gataataggt acagttatgg ggttagtaca tattttaggt aatctttcaa gtaatccaga
    54961 tgcattagga cctcaaattt ctgttgcatt tttggctact ttgtatggtg ttggttctgc
    55021 caatttaata tggttaccaa tagcatcaaa acttaaggct ataaatcaac aggaaataag
    55081 tgaaagactt ttggtgatag aagcaatatt atccatactt gagggtgata attctaattt
    55141 aatgacagaa aaattaaaaa tatttttaaa ttcaaaagaa ctaattgaac ttgaagaaat
    55201 tggtggtaga gctgaataat ataaaaggat ggaatgttta tgttgtatga tgaagatgaa
    55261 aaagaagaaa acaatgagcg atggctttta acttattcag acctcataac attacttatg
    55321 attttctttg taataatgta ttctatgagt aatgttgatg cggagaaata taaacaatta
    55381 tctcaatctc taaattctgc ttttggtggt tcttctggag ttattgaagg tggtaatagt
    55441 aaaatagaac cagtagttga accaggaagt aatgatttag ataatttaca aaatgctaag
    55501 tttaaaaaag ttggtgaaga aatccagaag tatttaaatg aaaatggtat ggctaattca
    55561 gtatcattaa gagttcaaga tagaggatta gtaataagtc ttaaagatac aatactattt
    55621 gatacgggga aagcagttgt aaaggacaat tccagagaga agattattca aataggtaag
    55681 atgttaaatg aaatgaatag ttacattaga gtagaaggtc atacagacaa tatgtctata
    55741 aaaaattcag agtttaagtc aaattgggat ttatcagtta tgagagcaac caatgttgtt
    55801 caacttctta ttgacaatgc aggtatagca ccagataaat tgtctgctgt aggatatggt
    55861 gagtttagac cgatagcaga aaattcatct gaagaaggta ggtcaaaaaa tagaagagtc
    55921 gatatagttt tagttgatag taaatatgat aatgtagaaa atgtttcaaa tgataaatag
    55981 ttaaattagc tgtctcaaca cagaattaat tctaaagggg atggcttttt tatgcgaaaa
    56041 ttaaaaatag atagatagta agttaccttt ttgtggtaat atatggtatc ttaaatatat
    56101 aatatttaaa taatatataa gctcaattaa aaaaatttta tagaggatgg gaaatgaatg
    56161 ggaaataaaa atacgaaata taaagataaa acaagagaaa ggtataataa aaaagttgag
    56221 aatttaaata aagaaaaatt aaataaagct aataaagaat ctaagaaagt agataagatt
    56281 gatgatatta tcaataaatc tagcattgta ttatgtgtac ttctagtagt gttttcatta
    56341 ctttacttat tcaaattagt tcaacttaat ataataatga tacttttagt aattacagta
    56401 gctattcaac agggattggt gtcatttggt gcatttagaa ataaaaatta tgtaaaagct
    56461 ttattttcta tatttgtaat tgtatgtttc ttaattgctt ttaaatatgt tgtaaatcct
    56521 gtttaaatat atcaataaac gttctataat taatataaat agtgaagtta tagttttaat
    56581 gctattgtaa attttataat ttgaaggagt agattttatg aataggtgta agtttgcaaa
    56641 attaattatc acattaatga tagttttatt acttacagga tgtagtttaa aaaaggaaga
    56701 taattataag ctagacccag aaaatccgat atcaatacaa atttggcatt attataatgg
    56761 acagcaaaaa atggcttttg ataaacttgt taaggaattt aatgacacag taggttctga
    56821 aagaggaatt attgttgaag cattcagtca aggtaatgta gttgatttat cagagaaagt
    56881 tttagattct gcaaataaaa aagttggctc tgaagatgta ccaaatatat ttgcagcata
    56941 ctcagatact gcatatgaaa tggataaatt agggctacta gtagatatgg ataagtacat
    57001 aagtaaagaa gaattaagtg aatatataga cgaatatgta gaagaaggta gaataaattc
    57061 taagggtgag tttaaacttt tcccaattgc aaaatcaact gaaattttga tgttgaataa
    57121 aactgattgg gataaatttg caaaagctac aaattcaaat ataaatgata taaaaacaat
    57181 tgaaggatta gtagagacat caaaaaaata ttatgaatgg acagatagtt taacgaaaga
    57241 gcctaatgat ggtaaagcgt tttttggaag agatgcttta gcaaattata ttattatagg
    57301 aagtaaacaa ctaggagtag aaattttttc tgttaaagat ggtaaagtta cattaaatat
    57361 tgatgaaaaa gttatgaaaa aactatggga taatttctat gtaccatata taaatggata
    57421 ttttgcttct tatggtaagt ttcgttctga tgatgcaaaa acaggtgata tattagctct
    57481 tgtaggctcc agttcaggag cagcatactt tccagataga gtaatgctaa atgacaatga
    57541 gagttataat attgaaacat ctgtttttca agcgccacgt tttaatggag aaggaaaata
    57601 tgctgtacaa caaggtgcag gaatggctgt aacaaaatct actaaagaag aagaatatgc
    57661 atcagtagaa tttttaaaat ggtttacaga taaagaacct aatataaaat tctctattgc
    57721 ttctggatac ttaccagtaa agaaaaaaac gaatgattta gaggttataa aagaagttat
    57781 gaagaaagat aatttgagcc tatctgataa agttgaaggc tcaatagctt catctattga
    57841 acaaattaac agttgtaatt tatatactaa taaagcattt gatggtggaa ctaaagctag
    57901 acaaatactt gaatattcaa tgcttgataa agcaaaagaa gatttaaata aaataaatga
    57961 attagtaaaa agtggaactt ctaagaagga tgcagtagca caatttaata atgataagaa
    58021 ttttgaaact tggtttgaaa gttttaaggc tgagcttgaa aaagctataa aaaaatagat
    58081 gaattggcag ttagtgtgtc gacaagcaca aaggtatagg tggaataagt atggaaaata
    58141 atctaagaaa aaacaattca ataatgaaaa agatgatatt tcccctaatt attgttatgc
    58201 taattcaaac aagtttattt tgtgccacaa ttttatgggg aggaactatt aagaaattaa
    58261 atgataattc gtttgacatc ttaaatgaaa gagtaattaa tcgtaaaaat tatatacaaa
    58321 atgaaatgtt acaaagatgg tcaaatacaa gtgaaacaga agctagaatt aattcctctg
    58381 taaaaaaagt cttaaatgaa aaaaatgctt taattgagga tgtaggcaac aatgaagaaa
    58441 ttaacaaaga cattataaga atcatatcaa atgatttaat atatcttttg agaaaaaatt
    58501 ctgttacagg agcttttata atattaagtg acaaaaatat taaagataat ccagtagata
    58561 gtaatggtga aataagtagg actggattat atataaggga tttagaccct aaatttaatc
    58621 caaatgataa ttctgatttg ttaattgaga gaggttcatc agatatagca agaagttttg
    58681 gaatatctat ggacagttat tgggaaccta aattttcatt taaaagtgaa aatgaacaag
    58741 aaggagatga ttttttttat aaaccattta gagctgcaat tgataatcca aatgtatcaa
    58801 gttctaattt gggatactgg ggaagtaagt ttttattgac aaatgcaggt gataggatta
    58861 tgacatatac agttccactt atttatgaag atggaactgt atatggagta cttggaatag
    58921 atttaagtgt aaattattta agagaattac ttccatactc agagataaat ggaaataaaa
    58981 aaggtaatta tattttaggt gtggatagaa atgatgatat ggcatttgaa aatgtaattt
    59041 caaatggata ctcattaaaa gaaaagtttt ggaatggttt acattctaat ttagagcaga
    59101 aggaatcgta taaaaatata tataagatta aaaataaaga taatgaatgt ggtaatggca
    59161 atatttatgc tagtgtacaa tacttaaatt tatataattc caatactcca tttgaaaatg
    59221 aacgttgggc tcttttgggt attattgaag aaaaaagtct tttatctttt tcaaaaaggg
    59281 tagagaaatt agttataata tctatagcaa tttctttatt aataggtcta ataggtattt
    59341 atgttgcatc tagattattt acaaaaccaa ttgttctttt agccaacaaa gttagaaaca
    59401 gtaatccatc aaaaccagta aatcttgata agataaatat atctgaaata gatgaattat
    59461 cttcagctat agaattactc agtgcaaatg ttgcagattc ctcatcaaaa ctatcgcaga
    59521 ttattgaaat ggtagatatg ccaattgggg cttttgaatt atacaaaaat gcagataatg
    59581 ttttttgtac aaaagaattt tttagtgttt ttattactga aagcaaattt gaagaatatg
    59641 gttatatgga aaaaagtaag ttccttaaaa aattaagggg attagataaa tatttgcaag
    59701 aaagttatga aacagaaaat acatatatat acaagtttga atctaaagat aaaaagccta
    59761 agtgggtaag actgaatatc tttgaagatg agttaaaggt tcttggcgtt gttgttgatg
    59821 tcacaaaaga gtttattgag aaaagaaaga tagaatatga gagagatttt gatattttaa
    59881 cgaatctttt aaataggaga gcttttcatt cacagataca agaaaaattt aagaataaag
    59941 atgaacttaa ggtagcagca ttcattatgt gggatttaga taatttaaag tatattaatg
    60001 atacatatgg acatgatgct ggtgatgaat atattagatg tgctgcagac atacttaaga
    60061 agtttatatc gtggaatggt atagtatcta gactttcagg tgatgagttt tatgtattta
    60121 tatatggata tgaaagtaaa gatagtataa gagatattat taattctgtt aagaaacaga
    60181 tgaataatac cttattaaaa cttcatgatg gaacagaatt taaaataagg gcatcagcag
    60241 gaatttcctg gtaccctgat gattcaatca actatgatga gttaatgaga tacgcagatt
    60301 ttgctatgta tcaaattaaa aatacaatca aaggtgaagt tagtgaattt gatattaata
    60361 tatataataa ggattcattc ttattgagca atagagaaga attaaacaag ttaattgatg
    60421 gtcaactagt tgaatatgca tttcagccta ttgtagattg taaaggtaaa gtatttgcat
    60481 atgaagcact tatgagacct aaaataaaaa cttttagttc accaatagat gtcattagat
    60541 tagctcgttc acagtctaaa ttatatcaaa ttgagcgtat tacatggttt aaggcactta
    60601 aatcatttaa aaaatacaaa gaaaaatttg gtgattgtaa actgttctta aattctattc
    60661 caaataataa tttatcaaaa gtagattttg aggaaattga agatttatat ggtgaatatt
    60721 taaatagagt agtattagaa ataacagaga atgataagat taatgaagat tttattgaga
    60781 aaaagaaagc atatatagac cattggaata tagaaattgc tttggatgac tttgggacag
    60841 gttataatgg agatgctgta ctattatata taatgccaga ctatgtaaag attgatatgt
    60901 ctattgtaag aggtattgat aaagatgaaa atagacagaa aatattaaaa aatcttatct
    60961 catattccaa cgaaagaaat attaaagtga tagcagaagg tgtagagaca aaaggtgaaa
    61021 tggaaacact aattaatctt ggaatagatt atatgcaggg ttactatatt agtaaaccat
    61081 catttatacc tgaagatata agtgataaaa ttaaaaaaga gctcaagata tgtcatgaaa
    61141 ataggaatga tgtggtttaa tagaggaaaa attaaattta tttttatgaa cttttagttt
    61201 ataattaaaa agaaaataat ataattataa attaaggtgg tggagctaat aatcacaaca
    61261 aatatagata taagaaagtt aaatgaaaat caattagaag cagttgagca tatagatggg
    61321 ccttgcatga tacttgcagg gcctggttca ggtaagacta gagtaattac atatagaata
    61381 gccaatatgg tcgtaaacaa aaacatagca ccaacaagaa ttttggcaat aagttttacc
    61441 aaggcatctt cgatagaaat gaaaaataga gctttgaatt taagtgatga tataagactt
    61501 aataaggtaa cctatggtac tttccactct gtatttttta aaattctaag atactttgaa
    61561 agatataatt tagatagtat atttgatgaa aaatcaaagc gaatgacaat aaaggcaatc
    61621 ttaaaaagtt taaatataga gaatgctgat gatgatgaga atataggaca agttataaat
    61681 gaaatttcct atgtaaaaaa tgaacttatg gataaaaatg aatttaattc agaagtatta
    61741 acaaaagatg agtttttaaa agtatacaac ttatatgaag aacaaaaatc taaagttaat
    61801 aaaatagatt ttgatgatat gcttataaga acttattatt tacttttgaa aaataagtct
    61861 gcactagaaa tggttagaaa tgtgtataaa tatatattga tagatgaatt tcaagatata
    61921 aataaagtac agtttgaagt tttaaagtta atttctagcc cattgaacaa tatatttgca
    61981 gttggagatg aagaccaaag tatatatgga tttagaggtg ctagaccaga ttttttgctt
    62041 gaatttgaac agtactttaa taatactaaa aaaataatat tagatataaa ttacaggtct
    62101 aaaagtgaga tagtgcatac tgcaaataga cttatcgaca aaaataagaa tagatatgaa
    62161 aaagttatta agtgtagtca aggtgatgga ggaagtgtta cctatatttc tccacatgat
    62221 tcagaggaag aagccttata tattgccaag gaaataattg acgaaataaa aaaagattat
    62281 gtagagtatt cagattttgc agtgatttat agaactaata tacagtcaag agcattagta
    62341 gatgtattta tggatatgag gattccattt gtagtaaaag attcagtaat tacaatatat
    62401 gaccattggg caagtcaaga tatactagct tatttaagaa taggtattaa tccaaaatca
    62461 aataaagatt ggttgagaat tataaataag ccttttagat atatatccaa agacagtata
    62521 aatatggtta aggatgaaaa agattttata acagcattaa taaataagtg taatcttcat
    62581 cctaaacaag ttaaaacaat aaatgatttg gaaatagatt taagctattt aaatacttta
    62641 aatcctaaaa atgcaatatc ttatattaga actagccttg attatgatag atacgtttta
    62701 gattattgta gcaacagaaa gataaagact aatggacttg tagagatatt aaatgaactt
    62761 gagagctcag caactaattt taatactgtt acagagtttt tagagcatat tgatagagta
    62821 aagactgagt taacggaaaa taacaagaat aagcagactg aaggtgttat atttacaact
    62881 atgcatagtg caaaaggatt agaatttaga aatgtttata ttataggtgt aaatgaagga
    62941 acaatacctc atgaaaaatc atatgatatt tgtaaggaag agaaaaaaga agaacaatta
    63001 gaagaagaaa gaagacttat gtatgttgct attacaagag ctgaagaaaa attatgtata
    63061 agctctactt taaataagta tggtaagaaa gttgataaat cattatttat taatgatata
    63121 aaatctccaa cgaaaaaaga aattgatagt attggtgtag gggataaggt ataccataaa
    63181 aaatttcatg aaggagaaat aattaaaaaa gatggaatta tgtttacaat aaagtttaaa
    63241 gatagagagc gaatcttgga tttgaaaact tgtttattga agaatataat ttatactatt
    63301 taatttagaa cctaaattta gatacaatgt attatttata tggatagact agtaagaagt
    63361 atattcttta ttgtgtgtaa gtaaaagaga tatgtgtaaa atgtattatt taagttatta
    63421 gaaaagagaa ataaacgttt aatatattat ttatagttgt taagaaaaag caaaactgtg
    63481 aaagatatta tttagcatta tttaagaaaa agcaaaactg tgaaagatat tatttagcat
    63541 tatttaagaa aaagcaaaac tgtgaaagat attatttagc attatttagt aaaaagcaaa
    63601 actgtagaag atattattta gaattattat agtaaaaagc aaaactgtag aatgtattat
    63661 ttaagaaata gctaaaaata taaaatatac tatttgtaat tatataaaga atatcaataa
    63721 atatacacag tagtatttat ataatttaca agcaaaaatt attaaaaaaa taaaaaactt
    63781 attgacaaaa atattataag gaagtacaat tgtattaaca atttaaggaa acaaatccag
    63841 tgatagagaa agtagcatat atggatttac agcgagttag ggattggtgt aagcctagca
    63901 atgaagttta tgtgaagaga gctctggagg agattatcag aaattttagt atgataattg
    63961 gtctgcccgc cttaagggat tgagaggata agtacttact tatcaaaaag agtggtaacg
    64021 cggatataat tcgtctctta gctgtaaagc taagggactt ttttgattta aaaatcaaaa
    64081 tatccatata gctaaagcta acaatcacaa attttgaaag taatagaagt atttatcaat
    64141 aagagtggta acgcggtaaa gtcgtctctt agtcattaaa gactgagaga ctttttttgt
    64201 aactcgaaac atttaagtat taaaatttga gggaaattat aattaaaaga gaggggtagt
    64261 taaaatgaaa gtatttaaaa aattattaag tttaggatta gtattaggat tgacattatc
    64321 gctagtagga tgtagcggtg gaggagaaaa gacaaagtta gaacaaataa aagacagtgg
    64381 aaaattggtt gttggtacta gtgcagaatt tcctccattt gaatttcaca aggtagtaga
    64441 tggaaaagat tcaataaaag gattcgatat aatgttggct gaagaatttg caaaagaact
    64501 tggtgtaaaa gttgaaatta aggatatgtc atttgatgga ttgataggtg ctttaaatgc
    64561 agaccaagtt gatattgttc ttgcaggtat gtctccaaca ccagagagag aaaagagtgt
    64621 tgatttctca gaattatatt atttaagtag aaatgcagtt atagttaaag atgcagatat
    64681 agacaaagta aaaactgaag acgatttaaa gaaacttaga gttggagttc aagcaggaag
    64741 tatccaagaa gaatatgtag ttaacacttt aaaaatgaca actacaaaat ctttaaaagc
    64801 aatacctgat ttaattacag aattaaaaaa tggaaacata gatgcagttg ttactaatga
    64861 agccgtttct ttaataaatg ttaaaaaata tgatggaata aaaatggcaa atactgaagt
    64921 tggaaaaaat gtaacagaag gtatggctgc agcaatcaaa aaagctgaca ataacaaaga
    64981 gtttatagaa ctattaaaca aaaagataaa agaattacaa gatggtaaga agatagaaga
    65041 atttttaaat gaagcatcta ctgaagctgc ttcaaattag taagaaagtt atgtgggaga
    65101 tgaaattatg agtttagatt ttagtttttt aagtagattt gggacttctt ttttggaagg
    65161 aacaggtgtg acagtatcaa tttctcttgt ggcattatgc tttggattta taataggtat
    65221 aattatctgt atggcaaaaa tatcaaagag caaagtatta agagcaatat catcaatcta
    65281 tattgaggtt ttaagaggga ctccattatt agtacaaata tatatagtat ggtttggttt
    65341 acctcaatta ggaataagat tccctatgtt gtttggtata ccaagtgaat ttatagctag
    65401 tgcatttgca ttatcagtaa actctggtgc atatgtggca gagatactta gatcaggcat
    65461 acaatcagtt gataatggac aaatggaagc aagtagatca ttaggattaa attattggtc
    65521 gactatgaga tatataataa tacctcaagc tataaagaat atattacctt cattagcaaa
    65581 tgagtttatt acacttgtaa aagaatcttc aataatatct gtaataggag ttgttgagat
    65641 aatgcgtact gctgatatag taaaaaatgc agcatttaga gcattagagc cattaatagt
    65701 agcagcagca atttactttg ttataacatt tactctatca agattagttg gattattaga
    65761 aaagaaacta tctgtgtcta actagatgag agcatgttta gcatttaggg aaaacataga
    65821 atagtaaaaa ggaaagtgat aatatgatta caataaaaaa tttaagtaaa tcttttggag
    65881 atttaaatgt attaaaaaac atagacttag aaatcgctaa aggcgaaata atggttatag
    65941 taggcccaag tggttctggt aaaagtacac ttcttagatg tatgaattta ctagaaatac
    66001 ctacaggtgg agaaataata tttgaaggaa aaaatttggt cgataaaaaa actaatattg
    66061 atgaggttag acaaaatata ggtatggtgt ttcagaactt taatttattc ccacataaga
    66121 ctattttaga taatataaca ttagcaccaa ttaaattaaa aaagatgact aaggaagaag
    66181 cagaaaaaaa agcagaagtt ttgttgagta gagttggtct tttagataaa aaagattcat
    66241 atccatcaca attatctgga ggacaaaagc aaagaatagc aatagctaga gcacttgcta
    66301 tggaaccaga tatgatgttg tttgatgagc caacatctgc tcttgaccca gaaatggtaa
    66361 acgaagtttt ggatgttata aaagaacttg ctaaagaagg tatgacaatg gcaattgtaa
    66421 ctcatgagat gggatttgct aaggaagttg cagatagagt tatttttata gatggaggaa
    66481 gtatacttga agataatact ccagaagaag ttttcggaaa tccaaagcat gaaagaacaa
    66541 aagcattttt agcaaaagtg ttataatata taaaaaggat gttattgaca ttagaaattc
    66601 aatacatcct tttttaatga tggttaatat aaattttaaa actaaagtta tattaatatt
    66661 aactttagtt tttcaaatct ttgcaaaaaa aaaagagctc ggggtaagct ctttttttcc
    66721 accgaattaa tttccgttac taatccgatt tttaataaat ataaaatata tccttatgaa
    66781 agggtattgg gaatagatat attaactaac tagggttacc agggggataa ccttaattta
    66841 ttataacaaa atgcgacaca aaaatcaata ttttttttgg aataaattat aaaagttatt
    66901 tttataacaa gtaagcttat aaatttaact tttatagtaa aaata
//
LOCUS       DAMKOJ010000011        65292 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000011 DAMKOJ010000000
VERSION     DAMKOJ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 65292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65292
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.011"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            71..415
                     /locus_tag="PC592_000812"
     CDS             71..415
                     /locus_tag="PC592_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF4054820.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEILAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(576..2672)
                     /locus_tag="PC592_000813"
     CDS             complement(576..2672)
                     /locus_tag="PC592_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDF4054821.1"
                     /translation="MIKFKLYISGLYSGNVIFDDDLLIEKLNPFTNKIESLKPISREE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWDKTHKDEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPNFIDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWKPMIHEREDGDSTINWIVSQEWSDGTVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNGMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPIEYYSVGSNIWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDSRLEEKCDSYIYNPKDPSIQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDVFSEEF
                     TITGDIKLEFFASSSARDTDWVIKIMDVDLDGNSIKLADGILSARFRNGFYESEFMEE
                     GKIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(2685..3845)
                     /locus_tag="PC592_000814"
     CDS             complement(2685..3845)
                     /locus_tag="PC592_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF4054822.1"
                     /translation="MNTLFSNPGSILAVMTLMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFTSFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(3864..4931)
                     /locus_tag="PC592_000815"
     CDS             complement(3864..4931)
                     /locus_tag="PC592_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HDF4054823.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVISVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNVPLYKVLGGFDSKVQTDITISIDKPEKMAIEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNIKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKSISGGF
                     VMDGDIMNLLNKPGLGIEVNL"
     gene            5282..5848
                     /locus_tag="PC592_000816"
     CDS             5282..5848
                     /locus_tag="PC592_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054824.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTPEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDVCMGEKIVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(6066..7052)
                     /locus_tag="PC592_000817"
     CDS             complement(6066..7052)
                     /locus_tag="PC592_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HDF4054825.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSISGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYISTFIQEKDF
                     TINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSKGEVEKFLSNEYKVTNEIDRMGCRLD
                     GESIKHINGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(7082..7777)
                     /gene="pxpB"
                     /locus_tag="PC592_000818"
     CDS             complement(7082..7777)
                     /gene="pxpB"
                     /locus_tag="PC592_000818"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDF4054826.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLKIDFDSLIESLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEIPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(7797..9017)
                     /locus_tag="PC592_000819"
     CDS             complement(7797..9017)
                     /locus_tag="PC592_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDF4054827.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(9046..9837)
                     /locus_tag="PC592_000820"
     CDS             complement(9046..9837)
                     /locus_tag="PC592_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HDF4054828.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVNKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNAEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            10424..11053
                     /locus_tag="PC592_000821"
     CDS             10424..11053
                     /locus_tag="PC592_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4054829.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAKTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(11164..12678)
                     /gene="glpK"
                     /locus_tag="PC592_000822"
     CDS             complement(11164..12678)
                     /gene="glpK"
                     /locus_tag="PC592_000822"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF4054830.1"
                     /translation="MEKKYIMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDKDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASIQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVNIDRPKIVETTALGAAYLAGLS
                     VGFYIERNEITSKWQVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            12922..13464
                     /locus_tag="PC592_000823"
     CDS             12922..13464
                     /locus_tag="PC592_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4054831.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLDIIFTEIRNFINKVHNVQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            13478..15970
                     /locus_tag="PC592_000824"
     CDS             13478..15970
                     /locus_tag="PC592_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4054832.1"
                     /translation="MNSNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     VCIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIILILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGVAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCLSLMFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSITPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKYLLD
                     KVQSADTTNITNITKEISTTMFDEKVPSIISKIQKNVQKGIDGTQSGINGIEEGESKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGIDKGIKGMEQGLKKQDKAIDELTT
                     AYNKIPTTEKIPTNNENNSNEQNQDNASNSESDATNNDSTENKNNNSNDNKPNLNEQK
                     ESLNAQIQKLKKTRNELNAKLQKNKAQKNELSKKLKSMESQKKELQSKLNNSINQKKD
                     MEKSLDTMQQQKKSLQAVLEKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFVILLFYKENKTR"
     gene            16388..16786
                     /locus_tag="PC592_000825"
     CDS             16388..16786
                     /locus_tag="PC592_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4054833.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     IVMSIADYFNVTTDWLLYGKEKVNSNNSVKEDKEDYLHINNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(17003..17212)
                     /locus_tag="PC592_000826"
     CDS             complement(17003..17212)
                     /locus_tag="PC592_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054834.1"
                     /translation="MCKLDSDGVIECCKAIDDFITALSNIKSLNMERLNILTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(17244..17453)
                     /locus_tag="PC592_000827"
     CDS             complement(17244..17453)
                     /locus_tag="PC592_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054835.1"
                     /translation="MDARRKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            17749..18168
                     /locus_tag="PC592_000828"
     CDS             17749..18168
                     /locus_tag="PC592_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054836.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSISEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKDKNLKKTEYNKTKDEKIDK"
     gene            18396..18851
                     /locus_tag="PC592_000829"
     CDS             18396..18851
                     /locus_tag="PC592_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054837.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(19062..19322)
                     /locus_tag="PC592_000830"
     CDS             complement(19062..19322)
                     /locus_tag="PC592_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054838.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(19585..19938)
                     /locus_tag="PC592_000831"
     CDS             complement(19585..19938)
                     /locus_tag="PC592_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054839.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQNKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLSQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(19955..25132)
                     /locus_tag="PC592_000832"
     CDS             complement(19955..25132)
                     /locus_tag="PC592_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome condensation regulator"
                     /protein_id="HDF4054840.1"
                     /translation="MKQNKLLQRGAYFNDKNILIDDFDKRYNDYDFVEFFTGISNSTF
                     GLKSDGNLYACGDNTGFQLGLGKDSSERRMFSKVKIDNVKYVSCGSKHSVAVTKDGFA
                     YGAGTSNVGQLGVIESTVYYEFTKLPIYDVKTVACGYDFTFVLKNDGTLYSAGLNSSG
                     QLGLGDTNNRATFTKVNIDSVKDVITYNQSVFIIKMDGTAHACGLNSNGQLGINSTLN
                     KSVFNKIEGMDNVKQIACGSSHTILIKNDGTMYTTGYNGVGQLGTGNNNNSIVFTLSS
                     INNVKYASCGNNHTMILKYDNTLFSTGQNNYGQLANANKDVASRNTFVKVNVENIKDI
                     KCGSQFNFLINGSKEIFVSGCNLAGQLGSFFHTTFLYEFSKVQSSNLDNYSGLLVNDD
                     YLYVTKDNSEFLNVKLSDNFQDYKKIELTDNNMFIVMNDGTLYACGLNNYGQLGLGDT
                     VNRSVMTKVDIDNVLDIKGNGNSTFVLKNNGTLYSCGLNNYGILGLKDEVNRNIFTKI
                     EIENVKEFCVESEYIIALNHSKEVYGWGYSANSNIERTSNYPDKQNINGIEKIATYYR
                     SVYMINSEGKLYVSGYNSYYQLGTGNSSSTNKTLVSKYRTVTLSTSSSNLSDLPKIVN
                     VFPFNYGCAIIDKSGFVYLAGQHRYPDTSKSNPSINDYSRYGSFIETTSSYYNTYFTQ
                     VNAFNGIEKVIGTSNNILYFKKGSTYVTGYPKTFGSSATGYKSYTTISSEYSNLGSLF
                     IITSSSSKLYGHGVANNGEFGNITNLDGVSSYDTGLKDIKDIIVKNNTVVVVDKNNNI
                     YVTGTNQFNKLGIGEYNNQPIRKFTNITEQSNSFIFMDDIKEITTSRNTMFIVKNDGT
                     AYATGNNSSGQLGLGDIINRNKFTQINLDNIKKISTSIDGNTTFAIRNDGALYSTGLN
                     TKGQLGLGDIVNRNTFTKVNIQNVRDVVLGTTHSHAIKDDNTLYSCGENTHGQLGLGS
                     ESNHPDVLTFTVNNITNVRDVYCSDTTTFIVKDTNIAYCCGYNNNSQLGMGNTTDQYS
                     FIKCMENVKEVIPNEINTYIITIYNTAYSTGLNTDYCLGLNSNSNQSSFSEIPISNVV
                     KVAPNRNNAVLLLTSEGDVYTAGKCSNGSGTGSETPEKIKKIASKAKDIGMNYRCGHY
                     VSDNGDLYGTGFNDCGQLGVGDVTKRDTFIKTNTRVKKILPLEYANIAIKDTNDIYIC
                     GLNNYGQLGVGNRYDSRNNDNRIFNYKHMNFVMGDLTSIKNRHNFILLNNKIVIPTTK
                     DIDYGLVLGNLYKGDLYTELPYENIKEVSISKTHIIILLNDGTMYGCGTNYHGELLQD
                     LSINQVDEFVQINVSDVKHVSCGDNFTYFIKSDDSLWSIGKNSEYQLGIGHNNPVTEL
                     QRITTVSSCKEVHCGKNYTLVVTTGNELFVQGYNDKGALGLGSDNENAIIKFFTKALT
                     DIREIKSYGSDHILVLKNDNSVWVTGKNRDVYKIEQPVEFLKEFTIVPISEDVNTVKD
                     VLATDNTLYIISEVGTTNAAIEITEKSISSIKIKIQDPNKDISRIEMLINGESVKSVS
                     DLTTEKISFEVPPDKIKIGENKILFRAYCKGDDLYASLFIFKESTGNSIIKDSYVMIG
                     NRMYKVVNTTSNEQDITITLDRGLEEDLNLGDPIYQLINKTKVQVKINKSDLFKDMKL
                     VEIKKSDSSYQEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(25154..26140)
                     /locus_tag="PC592_000833"
     CDS             complement(25154..26140)
                     /locus_tag="PC592_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF4054841.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVNIGDVNILTTDSKDLSGAINEVVKKIENISFDDVISGQIQTDISVLKNSY
                     NKLSEKVLDILIYLELESEVTVDEAGYWYDTLTNGNNIVAIEGLKLDLNRKCITGEIG
                     NVIFRDVVLPFSANRVRYIHDMDNNFVETKSSNTYLKEQKDITLSKYSYEIR"
     gene            complement(26141..26839)
                     /locus_tag="PC592_000834"
     CDS             complement(26141..26839)
                     /locus_tag="PC592_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF4054842.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSIVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(26836..27888)
                     /locus_tag="PC592_000835"
     CDS             complement(26836..27888)
                     /locus_tag="PC592_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF4054843.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMISGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGENGTVINNGTVI
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKRYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEINISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTAGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(27881..28309)
                     /locus_tag="PC592_000836"
     CDS             complement(27881..28309)
                     /locus_tag="PC592_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF4054844.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVSVRSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(28309..28635)
                     /locus_tag="PC592_000837"
     CDS             complement(28309..28635)
                     /locus_tag="PC592_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HDF4054845.1"
                     /translation="MANPINEFIGIIREEGKHHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMLDRQIETFDTETNQEHKHEVKNPFIDTFESGDMVIMFRIGEKFAIV
                     SKLVSL"
     gene            complement(28651..30180)
                     /locus_tag="PC592_000838"
     CDS             complement(28651..30180)
                     /locus_tag="PC592_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF4054846.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLMQSEVSYNFKDKLVEDIAK
                     QVFAENRISVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEGYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRKDFNTARRV
                     L"
     gene            complement(30462..30884)
                     /locus_tag="PC592_000839"
     CDS             complement(30462..30884)
                     /locus_tag="PC592_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054847.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKATVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(30884..33337)
                     /locus_tag="PC592_000840"
     CDS             complement(30884..33337)
                     /locus_tag="PC592_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054848.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASSRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNELNSNIMIILIFKAKSDEIEKTKNKLLGNLKKIGGK
                     VWKIVIKAKDMTKRVISSILGNLKRVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASSIISKVFPKLRLFAGKVWRGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQRDVDNYYEDLLDIADKTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSSKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KVTSKLVSSIKMAQLGGVL"
     gene            complement(33337..33504)
                     /locus_tag="PC592_000841"
     CDS             complement(33337..33504)
                     /locus_tag="PC592_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054849.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(33531..33977)
                     /locus_tag="PC592_000842"
     CDS             complement(33531..33977)
                     /locus_tag="PC592_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF4054850.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(34091..34519)
                     /locus_tag="PC592_000843"
     CDS             complement(34091..34519)
                     /locus_tag="PC592_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF4054851.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(34533..35597)
                     /locus_tag="PC592_000844"
     CDS             complement(34533..35597)
                     /locus_tag="PC592_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF4054852.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAILGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(35602..36045)
                     /locus_tag="PC592_000845"
     CDS             complement(35602..36045)
                     /locus_tag="PC592_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054853.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEESCFFVSILS
                     VICTPIMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYALNFSVTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(36294..36734)
                     /locus_tag="PC592_000846"
     CDS             complement(36294..36734)
                     /locus_tag="PC592_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054854.1"
                     /translation="MENKKDILFKETDERLHNYKYLDIKIKNINLDIKRYENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKIEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIVKLSEIL"
     gene            complement(36838..37035)
                     /locus_tag="PC592_000847"
     CDS             complement(36838..37035)
                     /locus_tag="PC592_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054855.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            37204..37524
                     /locus_tag="PC592_000848"
     CDS             37204..37524
                     /locus_tag="PC592_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF4054856.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFDVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            37606..38112
                     /locus_tag="PC592_000849"
     CDS             37606..38112
                     /locus_tag="PC592_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054857.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGMKIISLL
                     SNLKQNTKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIIGIINSGVTCVYEMADILNVEINFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            38813..39568
                     /locus_tag="PC592_000850"
     CDS             38813..39568
                     /locus_tag="PC592_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF4054858.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(39711..40139)
                     /locus_tag="PC592_000851"
     CDS             complement(39711..40139)
                     /locus_tag="PC592_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF4054859.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(40560..40760)
                     /locus_tag="PC592_000852"
     CDS             complement(40560..40760)
                     /locus_tag="PC592_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF4054860.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(40943..42112)
                     /locus_tag="PC592_000853"
     CDS             complement(40943..42112)
                     /locus_tag="PC592_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF4054861.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANIEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            42348..43169
                     /locus_tag="PC592_000854"
     CDS             42348..43169
                     /locus_tag="PC592_000854"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HDF4054862.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVHFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDENILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(43245..44636)
                     /locus_tag="PC592_000855"
     CDS             complement(43245..44636)
                     /locus_tag="PC592_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4054863.1"
                     /translation="MLVGKKFNNKKIVTLRTVFVRYSSLFFAITVVLVSILILSFPIL
                     LSLNIILPANYVEKQIYENKDKIISSKQVTKDLIPDLCEYGVYTLNGKVISGTFNKNE
                     SKEVWDLMRGFERRTITSSKNYIKLSRKNEVCIIRYSIVAEFVSPTLRTYLPKPELLG
                     MIIFSIIFLIEIIILSKLFGKKLNAEMELLKNTTEKIEQQDLDFVIESSKIREINNVL
                     FSMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPEL
                     SEYMEYIAKGATQIEKYINTLIEISKTETGYILNKEVINVSEFIEDILIQIEALARTQ
                     NLNVEFSKQGNLPESITIDKELLFRAIMNVISNAIDYSPSQSKLYISVSVSNKYLKFV
                     ITDCGSGFSKADLSKATGQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILHIENSIK
                     TGGAMVTIEIPIV"
     gene            complement(44770..45540)
                     /locus_tag="PC592_000856"
     CDS             complement(44770..45540)
                     /locus_tag="PC592_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF4054864.1"
                     /translation="MTQLVRIFCSDLIKLKRTFIILMHFCIALIGMGLCLGYYKYSSA
                     DDISKIAAYLQVIAIAFPLLSSIMCSLCIEQEYYSGSYKHMLTSSNPKYLTLISKYII
                     LICLGFGATLVSVLGFKFGVSSISNEVYFTLDFYMISIMILVGSNLFVYILHLFLSLR
                     FGKGASIGVGIVETLLSAVLLTGLGARIWPYIPCVWGVRFISIWSSFSSSKTIEYIKV
                     ESIKGYQSIGLVCGFVTILAFIILCIWFSKWEGKKSEE"
     gene            complement(45542..46261)
                     /locus_tag="PC592_000857"
     CDS             complement(45542..46261)
                     /locus_tag="PC592_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF4054865.1"
                     /translation="MEKLVRAEFQKMKRTFGIRLIWIAPIFSIIITFLLGGGQNGVYN
                     WWYTMFLPGVLTLISSLIVQKDEKKKYRGILSLPIEKKDVWTGKILYCIICCFITSII
                     FMIGIFLVGMLYKEVISVSQNIIGTILLVLLFMWQIPLCMFLASKFGMFITIIINMFF
                     TIIGVAVFSTTEMWYAFPYSITPRLMAPVLHILPNGLPVPEGSEFLNSNVILPGVLIS
                     IVLFILLSLATNAWFNNREVK"
     gene            complement(46263..46970)
                     /locus_tag="PC592_000858"
     CDS             complement(46263..46970)
                     /locus_tag="PC592_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF4054866.1"
                     /translation="MSNYILEVKGVSKKFKDEVVVDNISIAIKHNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLKIVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVLGYQGEVSKEQN
                     LEELFMKVVAENRKRGN"
     gene            complement(47090..47626)
                     /locus_tag="PC592_000859"
     CDS             complement(47090..47626)
                     /locus_tag="PC592_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054867.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDDD
                     VREETTSKMINSKNTTKIPIEIISKDGKIVKYLQIDEESTLKDKLRLILDTLSKEYFN
                     GLDMEVEVKEKDNLVKINLIEPDEKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(47728..48798)
                     /locus_tag="PC592_000860"
     CDS             complement(47728..48798)
                     /locus_tag="PC592_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF4054868.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDVSVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSKDEGVFINNIEEYIPENVNIKEKIGRHSNYDNEFNLYSNMPIAKYLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEVIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNRLEL"
     gene            complement(48791..49849)
                     /locus_tag="PC592_000861"
     CDS             complement(48791..49849)
                     /locus_tag="PC592_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDF4054869.1"
                     /translation="MSLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIISSLGSPKSIAKELILQTKEKNIQEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMSTDILNGKFSRFKSNIKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSVTIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGIEILAWQLLLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLKDIENKKGEDKYE"
     gene            complement(49836..50168)
                     /locus_tag="PC592_000862"
     CDS             complement(49836..50168)
                     /locus_tag="PC592_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF4054870.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DKGGNELE"
     gene            50367..51488
                     /locus_tag="PC592_000863"
     CDS             50367..51488
                     /locus_tag="PC592_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HDF4054871.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKESIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDFSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKEICCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSDSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYRLVS
                     NEFDSIINFMKKNLEEFKTVIHPEKIADYISELIDKHYS"
     gene            complement(51616..53514)
                     /locus_tag="PC592_000864"
     CDS             complement(51616..53514)
                     /locus_tag="PC592_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HDF4054872.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLDDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVSPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEEGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAVENKDYQAASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            53829..54605
                     /locus_tag="PC592_000865"
     CDS             53829..54605
                     /locus_tag="PC592_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF4054873.1"
                     /translation="MEYIIFDLEFNQGFDKKFNKTISNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKEIHPFISRMTNIKDSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFILEDAKQRKNK"
     gene            complement(54697..55449)
                     /gene="xth"
                     /locus_tag="PC592_000866"
     CDS             complement(54697..55449)
                     /gene="xth"
                     /locus_tag="PC592_000866"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDF4054874.1"
                     /translation="MRFISWNVNGIRACAGKGFLDFFKEVDADVFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLISADIHTEVLGSDHCPVELEIK"
     gene            complement(55570..56520)
                     /gene="galT"
                     /locus_tag="PC592_000867"
     CDS             complement(55570..56520)
                     /gene="galT"
                     /locus_tag="PC592_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDF4054875.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDKEC
                     PFCKGNEAYATDALFEIEGEEGWLVKSVYNKFPIIDDMARDIYGVHEVMIESSKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLNRRVVYNGEAFLVIIPYATKYSGE
                     VRIIFKDKIKFGELNDNNIKELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEELTKKLKID"
     gene            56905..58101
                     /locus_tag="PC592_000868"
     CDS             56905..58101
                     /locus_tag="PC592_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF4054876.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYNMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(58320..58772)
                     /locus_tag="PC592_000869"
     CDS             complement(58320..58772)
                     /locus_tag="PC592_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4054877.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(59073..60518)
                     /locus_tag="PC592_000870"
     CDS             complement(59073..60518)
                     /locus_tag="PC592_000870"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDF4054878.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYNSSYAVSGQTYTRKLDYQVVSILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINKRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(60657..61568)
                     /locus_tag="PC592_000871"
     CDS             complement(60657..61568)
                     /locus_tag="PC592_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4054879.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKKY"
     gene            61825..62649
                     /locus_tag="PC592_000872"
     CDS             61825..62649
                     /locus_tag="PC592_000872"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF4054880.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKRPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            62689..63219
                     /gene="lepB"
                     /locus_tag="PC592_000873"
     CDS             62689..63219
                     /gene="lepB"
                     /locus_tag="PC592_000873"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF4054881.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRIIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKIFAMGDNRENSNDSRFPDVGMIDEDEILG
                     KVMVRLLPLDNIGKVD"
     gene            complement(63299..65080)
                     /locus_tag="PC592_000874"
     CDS             complement(63299..65080)
                     /locus_tag="PC592_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF4054882.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINKDVKVVPKVTPFKGIN
                     TDLLYVKDGKILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLDEYLNDENDEINLNLFLLDVC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEEVQIKDVISIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLIIFTHTKQLRNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKAFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        21572 a        10796 c         7396 g        25528 t
ORIGIN      
        1 tagtatagac tttttttaat ttattattta gatttttaat agatttttta actatggagg
       61 tatttaaaat atggaaataa agagatatga aggaactgga agaatgagta gagctgtagt
      121 tcataacaat acagtttatt tatgtggaca aactcatgct gaaggaggag taattgaaca
      181 aacaactgaa attttggcta aaatagaaga tttattaaac aaatatggtt cagataagca
      241 acatttacta tctgttacta tttatttaag agatatgaaa gactttgaag ctatgaactc
      301 tgtttgggat gcttgggttg aaaaaggatt tgaacctgct agagcttgtg ttgaagctag
      361 acttgctaga gagcatttgt tagttgaaat gagcgttgtt gcagctacaa aataatcaat
      421 ttagcttata gggggggctg tctcaaaata gagagataag cctctttttt attgttgaaa
      481 tgatgaaaat atattcgatt tcatataaaa gaaagtgcct cacgaaccaa aaagttcatt
      541 ttgagacacc tcctcactat ttaatctata taaatttact tattctctat tggcaatatc
      601 aatttagatg gatatttacc tccatgataa atcgtattct ttgcttctat atattcaata
      661 ctattatatc cctctgtcgt gttactattt tggaaaataa agtttttagc actagatgtt
      721 atgtctagtc taattttatg accaacttta aacgtgtttg atatttttga agttataatc
      781 gtaaatttat aaatttttcc ttcttccata aactctgact cataaaaacc atttctaaat
      841 ctagcactaa gtataccatc agctaattta attgaatttc catctaaatc tacgtccata
      901 atttttataa cccagtcagt atctctggca gaacttgatg cgaaaaattc taactttata
      961 tcacctgtta tagtaaattc ttcactaaaa acatctgatg tataacacaa catgtcactt
     1021 cttttttcta aatctttgta gttatttgga actccaactt cattctctga catatcaatt
     1081 agttgtattg atgggtcttt tggattatat atataactat cacacttttc ttctaaccta
     1141 ctatcaaata ctaatctacc atttcctaaa gatgtgttag catttccatc acttattaaa
     1201 tacatactct tatctatctt gtttattatt ggccaatttt cttctgtctt ccatatatta
     1261 gaacctacag agtaatactc tattggagca gttgtatcta tgttattttc tatacctttt
     1321 aagtatttat caaaccataa cagataatta taatctaaat catatcttaa tgaactattt
     1381 cctaaagaaa taccatttat atctcttaaa gtatttgaat tatgcatcca tggacctaga
     1441 atagcctttc tctttccttt ttcatagtct tttataacat ctaaggcctc tgtagttccc
     1501 ataccattat catcatacca cccagataca accaacgcag gtacatttat tttatctttc
     1561 tgtaaatgcc aatccatcaa atcccaatac tcatcttttt ctactctctt taaccattct
     1621 tctagaaatt caattctata cccaagagct tcaacaggta tattctctat tggtcgtatg
     1681 tttaaaacat catcccaatc atctcttacc attttacttc tatcaacttt atttcttgat
     1741 accataaacg cccatgcaag cataccagat acgaaagctc ctccttttct tggtatgtca
     1801 ataaaagggc ttcctgatgt tactatacta actaaagctt taagatgctt attacctgaa
     1861 gatgcagctg cccactgaac atagccaaga tatgatgctc caagcattcc aactgttcca
     1921 tctgaccatt cctgtgatac tatccagttt atagtactat ctccatcttc tctttcatga
     1981 atcataggtt tccacttacc ttctgattcg tttcttcctc taacatcctg tattacaaca
     2041 gcatatcctc tttgtacata tttataatat atttctttat cattttcttt tccatatgga
     2101 gttctcataa gaattgttgg tgcttttttg gtagaatcta taaaattagg gagatataca
     2161 tctgtagaaa gttttatacc atctttcata tcaatcatat aatttccacc aaatcttata
     2221 gaatatatct cttcatcttt atgagtttta tcccattctt ttaatacagt atactcttca
     2281 tatccatcca taattaatat agtacaagtt tctctggata aacaaataaa acctactatt
     2341 ttattatcta caataattat atctagtggg aactttttat ttctttgaac ccatatatat
     2401 tcattaagtt tagaatgcgt ttctcctaag ttatttataa ctgtgtcttt atctgtgttt
     2461 actaaacttt tagtatatac atcaaagtta ttaaataaag actttaaatc tatttttgta
     2521 agatttaaat agtatgtatt ttcttctctg cttattggtt ttaaactttc tattttattt
     2581 gtaaaaggat tcaacttttc aattaataaa tcgtcatcaa agattacatt tccactgtat
     2641 agtccagata tgtataattt aaattttatc aattaaattc ccccctataa tcccagagac
     2701 atctttattg catatgccac tgatatacct gcataatttc ctaatactcc accaattact
     2761 cccattacaa ctgctacact tacaagtgaa ttccattttg cagaagcagc tactaaagct
     2821 gaagtaggac catcagcaat tgctcctact atagaaagta ttacatattg atattttatc
     2881 tttaaaagtc tagttatgcc taaatggaac acaaaagaag taaaaattat gctaaaacag
     2941 taaagtgtta tagtaaaagt tgaacctaaa aactctttta tatctactga aaaacctatt
     3001 gtacataaaa agaataatgc aacaaataac cctaaatcta aatttccctt tagtttcttt
     3061 actggcttta attgagcaat tataattgaa attgttgtaa ctaaaagtat tcttgctgca
     3121 ctactaaagc ttgaattgaa atatccagca agtattgttg agacctctgt aacaacaaaa
     3181 cctatagcca acatccaagc gatatcttta atactccact cttttgactc cataaattct
     3241 tcattttgac aatcttctaa ttctgattct tctacatgat atggccaaag ttttttaaac
     3301 ttctttgagt tttttaatat ggctggtaga gcaaacataa atatcaatgt tggtactcca
     3361 attacatagt ctgctgcatt tgccgcagca agagtttgtc tacttacatt aagacctgtt
     3421 ccaatggctg taagattagc acttccacca gtgtatgtac ctacaaacat tccagcaact
     3481 ttccaacctt ctgatatttt ttctgcaaat actagcccaa ataaaaatgc catgatactt
     3541 acagttaata ctgctacaaa aattgcaatc aaaggttctc ttgataactt tgtcatttct
     3601 tttaaatcaa cactcatcaa cattatagtc atagaaactg gaatcgcata tgttgaaata
     3661 gttccatata attcagtact tactggaact acttttaagt ttgaaagtat tattcccatt
     3721 atgattattg taagtgctgg tcctaagctt ttaatggctt tgtatctttg taagtaaaaa
     3781 cccaatgcaa tcattaatgt cattacagca agtatactac ctggatttga aaaaagtgta
     3841 ttcatattta acctccaatt ttatcataag tttacttcta ttcctaaacc tggtttattg
     3901 agaagattca taatatctcc atccattaca aatcctccag atatactttt tgattcttca
     3961 caaaacataa agctatcaag gtcagcttct gttatattct ttttagatgc tattaaattt
     4021 gctgctgctg ttataccaat tctcgtttct agcatacatc ctaacataca atttactcca
     4081 cttgcctcag ctatgttgtt gatttttata gcaggatata ttccacttga cttcatcaac
     4141 ttaatattaa atgtatcaac tgcattcttt tttatagctt taattgcatc tattggtgaa
     4201 tgcaatgatt catctatcat aatctttata ttactcttat ttcttatgta agcagtacca
     4261 tctaaatccc agtgtggaag tgcttgttca attgcatcaa cattaaattc ttccaatttt
     4321 ttgatagtat ttatactgct atttacgttc catccttgat ttgcatcaat tctaattctt
     4381 atactctctc caacagcttc tctaattaac tttacagctt caatatcatc ttcaggattt
     4441 atacctgctt taagctttaa tatcctaaaa ccttctttta ctctttctaa agcttctatt
     4501 gccatttttt ctggcttatc tatacttata gtaatatctg tttggacttt actatcaaaa
     4561 cctccaagaa ctttataaag aggtacattc ataatttttc ctttaatatc atataaagct
     4621 atatcaatag ctgcttttgc agaagtattg cctataataa ttccatccat gattgtatgt
     4681 atggtttcaa tatctagtgg gtctttacct attaactctt ttttaaacat aagtaatacc
     4741 gaaataacat tgtccaaaac ttcacctgta actgctgcaa gaggtgctgc ttctccaaat
     4801 ccacaatagc cttcatcagt ttcaattttt aaaattatac tttctccata ttcaattact
     4861 ccaaatgaaa ctactacagg tttttttaat ttaattctca gcttttcaaa tttgatatct
     4921 gttatcttca tattaccctc cttatttttg aagttataat tcaattttta aaattttata
     4981 ctttaaatta tattattact tcaatatata tgtcaagata atttactgaa aatttacgct
     5041 tttccaaaat ataatgtaat aatattaatt caattaacac tcttccatta aattttttta
     5101 ttattattct ctttatgtta atttagcaat aatttatttt catagacttt tctttgcctt
     5161 taattaaatt ttaattgtca aaatctacta agtattctta ttgccactac ttctatgtta
     5221 tgctataatt actttgtttt aagcgaatat tttatattaa ttttattatt tggaggttct
     5281 tatgctaggt gaaaagatga gaaatataag aaaaagtaag aaaaaaacat taagtgatgt
     5341 ttccaaattg acagatttat ctataagtta tatctctcaa atagaaagag atgctattga
     5401 accatcctta tcttcattga gaaaaatcgc tgaagtttta gacactcctt tatatatgtt
     5461 tatggatgat aacaatactg atgatttagt cattagaaaa gaagatagag ttatgatgaa
     5521 atttccaaag agtgaaatgt tttacgagat agtatctcca atgcctacac ctgagtttac
     5581 accttcaatt ttatttgtag agtttgaact taaaccagaa agcgaggatg ccaaagatta
     5641 tatctatcat gcatcagaag aaatcatggt ggtaacaagt ggtgtggtgg atgtttgtat
     5701 gggcgaaaag atagtgagat taaatccagg tgactcaaca tttataaaag ctaatgtacc
     5761 acataaaatc atcaacccaa gtaaggatac aatagctcgt ggatatggag ttatatcacc
     5821 tccaatttgg ccaataaaat ctaaataaat tcaataaaca tatctacttt ttatagatac
     5881 tacaatagat ttaaatatca cttttatttt aaaattgaag tatttattta aatttaacat
     5941 atttaatcaa actaaaaaaa tagctatttg actaatctaa accatcttaa ttatggtaaa
     6001 tagtaaatag ctatttgtaa gttatatttt aaattataat aaaaattata tttattaaaa
     6061 ttaaattaaa ctgctatatc atttaatact tttgctttta caactcttat attcttcatg
     6121 ctcttgtaga tatcttgaat cttatcttct tgttctctca atagtctatg tgcttcatat
     6181 atatccacaa gttcaaattt tactacatca ttcggctttg cttgtgctaa cttatataaa
     6241 tctacactta taacgtttcc tatcttagta taaccaccac tagtctgtct atctgataac
     6301 attataatag gttttccatg accaggtact tgtatagctc cataagagat accatcagat
     6361 ataatatctg ctccattaat gtgctttata ctctctccat ctagtctaca tcccattcta
     6421 tctatttcat tcgtaacttt gtattcattt gataaaaatt tttctacttc acctttagaa
     6481 aaagcatcaa attgaggacc ttttacaatt cttagtacga tttctgagct ataagttgga
     6541 atatattttg aatttaattt tttatttatt gtaaaatctt tttcctgaat aaaagtactt
     6601 atataatctc cttttttaag tgctctacct tcaaacccac caattttagc tcttgtataa
     6661 gttgacttac tccccattgc aagtggaaca tctattccac cagagattga tacgtaggct
     6721 ctagcacctg atttcacacc tctaaatgat aatacatcac ctggatttat ttgatatgac
     6781 ctccagtttt gaatttcttt tccgtttatt ttagccccta aatctccccc agttactgct
     6841 atttgcgtat attcatcaaa ggtaattgta gggcctaaca ttaaaacttc taaagaagcc
     6901 tcatcttcag aatttcctac taatatattt cctactctat gtgcatactc atccattgct
     6961 ccacatccag atacaccata ttgaccatat ccaactctac ctctgtcttg tattaatgtt
     7021 tggaaacctc ctaattcaac tttgaatccc atatatacca ctccctgtac tataacgata
     7081 tttaaatact taagttattt ttttcgattt ctataaattc atctaatgtt attggaacaa
     7141 attttataaa gtctccagct ctaagcaaaa tctgttcttc tctattttca tcatataatt
     7201 ttaaaggtgt tctaccaatt atttgccatc caccaggact atcgatagga tatacaccag
     7261 tctgagaacc tgctattcca acactcccac cataaatttt ggttcttggt atttctaatc
     7321 taggtgtagc tattctttca tccataccac ctagatatgg aaatccagga gtaaacccta
     7381 gcatatatat caagtattct ctacttgtgt gtatttttat aacttcatct acagtgagat
     7441 tattgtaact tgcaacattt ttaatatcta taccaaaaac ctcatcatag catactggaa
     7501 tctcatgtat tttaggtttt ggtaatacta tactttccaa attatcttct atttttttta
     7561 aactctcaat caaactatca aaatctattt ttagtggatt ataacttatc ataagtgacc
     7621 tatatgttgg caccatttct gttacaatac ctttaagatt tgatatttct attgctctca
     7681 taaatgaaat tacttttttg tttatatctt ctgatatctc atttccaaat tcagcaacca
     7741 ctgccttatc ccctgatatc aagtatctag tttccataaa tgtcacctct tctaaattaa
     7801 gcaaataaag cacctaggct gctaagagaa gttattcctg tatatgcaga tattaaaact
     7861 actattagtc caaatattaa gagccatgta ggatgcttgt aatctccaac aatatctttt
     7921 ctcttagatg ctataagcat aattcctaat gtgattggaa gtatcaatcc atttaaagcc
     7981 cctgctaaaa ttaataaagt agctggtttt cctataaatg ccattataag tgttgatatt
     8041 gctataaatg ctattatgaa atatttttca tatttatcta taaaaggatt tagtgtcttt
     8101 aagaaagaaa ctgatgtata ggcagctcct atgactgatg taattgcagc agaccataat
     8161 acaagcccaa agaatttata tcctattgct cctgcactaa atttaaaagc tgaagcagct
     8221 ggattttctg ggtcaagttg aagacctttt gaaactactg ctagtattgc taaaaataaa
     8281 agaactctca tcattgtggc aactaatata cccaaaagag aagatttagt tatttctttt
     8341 atattttctt ctcctgttat tccaccatct attaatctat gtcctccagc aaaagttata
     8401 taacctccaa cacttcctcc aagtagagtt attattggga atatcaatcc ttttggattt
     8461 tctggtttta ccattctaga aactgcctct ccaacaggag gatgatttga tattgctaca
     8521 tatccaacta taattatcat tcctaatgct aaaaatttag ttatcttatc tactagagaa
     8581 tttgaatttt ttgacataaa tacaaatata gctattaatc cacttaatac agttcctaat
     8641 gtcatattca tattaaacat tacattcata ccaagtgcag ctccaccaac atttcctata
     8701 ttaaaagcta atcctccaag agctactaaa aaagctacta aatagcctaa tccaggtatt
     8761 attttatttg ctatatcttg acctctaagt cctgatacac caattactct ccatacattt
     8821 acttgagccc ctataaaaag gattgttgta attaaaatta caaatgaaaa attcggtcca
     8881 aaatcttgag taaattgtgc agtctgagtt aaaaatcctg gcccaattgc tgatgttgcc
     8941 attataaatg cagcccctat aagcgctcca acatcttttt tatttttagt tttatctgta
     9001 atattttttg tactcatatt ttatctcccc ctcatgttat cagtcttata ctatgttctc
     9061 tgatgaacaa acttctatgt tttctaatgg acaaacttct atactttcta attcaaaacg
     9121 ctttcttatt tctttaacaa actctattgc ttttggattg tccccatgta cacatataga
     9181 atctgctttg atatgtataa cttcacctgt taaagtttct acagttcctt cttttaccat
     9241 cctaacaacc ctatctattg catgttttgt atcatgtata actgctcctt ctgcatttct
     9301 tggaactaaa aaaccattat tatcataagc tctatctgca aatacttcat ttgcaaacct
     9361 aagtccaatt tctttagcag aatttatcat ttcactatta tatagcccca acaatataat
     9421 atctttattg acttcatata tagcttcaca aatccccata gccaactctt tatctttagc
     9481 tgccatattg tataatgctc catgtggttt cacatgttgt atattacatc catttgaact
     9541 tgcaaatgcc attaaagcac ctaattgata ttttgtataa tctttagctt cctgcttcgt
     9601 tattttcatc tcacgtcttc caaatcctat taaatctaga aaacctggat gtgctcctat
     9661 tttcactcca ttttttttag ctagctgtac tgttttttcc atatgactag ggtcacctgc
     9721 atgaaaccca caagctatat tggctgatga aatatatttt aaaacttctt catctaaacc
     9781 aatcttatac gttccaaaac tttctcctaa atcactattt aaatctactt tatacaattt
     9841 atgacccccc ttgctaacat tttgatagaa taagtagttt caatttttaa attttgttta
     9901 ttttatatat tgcatgaaat attttattac ttgtattcaa ttttattttt gcaactattc
     9961 tattgcattt aattaatata attttaccat ttaaggaata tttttgcaat tattttaatc
    10021 aaacattcat ttgtatttct ttttcaaaaa atgtttttac cattttttag ttaacattta
    10081 attattttca cttaaaacaa aggctttaac cttcattttt aaagtatttt tcatttttaa
    10141 tcactttata tgcaagacag aatcattttt cttcattcat ttgtttgttt catctatata
    10201 attatcattc tttgtaaata aaatatcttt atatttttat aattaattct ttatatagtt
    10261 ttaagtataa taaaatcatg tatactaaat gcatgttaaa atattatttt aaaacatgca
    10321 caatatttgt acatattgta gacatataaa cctataaatt atacaatagt attgttaaga
    10381 ttatataatt ttttaacata aattttgtat tgggggaaaa acaatggata aaaactatac
    10441 gatgccaata taccaaaaaa tagcgttgga tattgcaaat aaaatataca cgggtgaaat
    10501 acaagaggat tcagtattat ttggacgctc tgttttggct ggtaaataca atgtatctcc
    10561 agaaacgata agaagagctg tcaaaatttt agaggacatt ggcgttgtta aaagcataaa
    10621 gggtaaaggt gttattgtac tatctccaga caaagcttct tcttttataa aaaaatatag
    10681 agatattaca aatatatcat catataaatc aacactttat aatttaatag atactaaatc
    10741 taatttagaa aatgaaatat tagatactat aaataaaatt ttagactact ctaacagact
    10801 tgaaataatc aatcctttag tgcccgttca gttcaccata aattctaatt gcaaatatat
    10861 tggtcaaaca gctgcaaaaa ctaaattttg gcaaaataca ggtgctacaa tagttgcaat
    10921 taaaagaggt gaagaactta taatatctcc tggaccgtat attgaatttc tagaaggaga
    10981 tattctctta gttgttggtg accaacatat ttacaactct ataccaatgt ttttatatga
    11041 aaatgaaaag taaattatat aatttagtat gattatataa aaatacaaaa ttaacaaaaa
    11101 aagagcttca tattttacat aaagctcttt ttaaattcaa ataaatttaa ccttgattaa
    11161 tttttaaata tccaattcat cttctttttc ccagcttaaa gctcttgata cagctttttt
    11221 ccagccttta tataatttac atctcttctc ttcactcata tttggattaa actctttttc
    11281 tacttgccac tttgaagtaa tttcatttct ttcaatataa aatccaacag acaatcctgc
    11341 taaataagca gctcctaaag ctgtagtttc tactattttt ggtctgtcta tatttacatt
    11401 taatatatct gactgaaatt gcattaagaa attattatta cttgctccac catcaacttt
    11461 taatgacttt aattttaatt ttgaatcatt ttgcattgct tctaaaacat cctttgtctg
    11521 ataagcaatt gactccaatg tagctcttac tatatgttct ttttttgctc ctcttgtaag
    11581 acctaaaatt gaacctctag catacatatc ccaataagga gctccaaggc ctgtaaatgc
    11641 tggaactaca tatacaccat tagtatcctc tactctattt gcatacattt cactatcttt
    11701 tgcagattcg attatcttta attcatctct aagccattga attgatgctc ctccaataaa
    11761 tatacttcct tctaatgcgt atgttacttt tccatcaacc ccccaagcaa ttgttgtaag
    11821 taacccatgc ttagatttaa ctatgttact gcctgtattc ataagtaaga aacaacctgt
    11881 tccataagta ttttttgcag taccttcttc aacacaattt tgaccaaaca atgctgcttg
    11941 ttggtctcca gcacatccag caataggtat tttagctcct gataacatgc gctcatctgt
    12001 atgaccataa acataactag atggttttac taatggtaac atgcttattg gtatatccaa
    12061 ttctcgtaat atatccttat cccattctaa atcatttata ttgtacatca ttgttctaga
    12121 tgcatttgag taatctgtta catgtacttt cccacgagtt aagttccata ttaaccatgt
    12181 atctatagtt ccaaataata actctccttg ttcagctttt tccctagctc cttctacatt
    12241 atctagtatc cattttactt ttgttgctga aaagtatgca tctatcaaaa gacctgtttt
    12301 ttcttttatt gattcttcca atcctttatt tttaagttca tcacatattt ctgatgttct
    12361 cctacactgc catactattg cattataaat tggtttccca gtatacctac tccaaacaac
    12421 tgtagtctct ctttggttag ttattcctat tgaagcaatt tcttctggtc ttatacctgc
    12481 tgtttctata acttctctca ttactccact ttgtgaaccc catatttcca tagggtcatg
    12541 ctctacccat ccagcttttg gataaatttg attgaactct ttttgtgcaa tttttactat
    12601 ttcgcctttt ttattaaata gtatagctct tgaactggtt gttccttggt ctaatgccat
    12661 tatatacttc ttttccatca tcatattctc cttatcatat aaatatttaa tttattaaaa
    12721 agaaaattta acattgtata tttcaataaa taatcatact taagtacaaa tttaatacaa
    12781 tagataattt ataagaagac acttattttc tatcatatct acataataat attatacatt
    12841 atagcttaca tattgattaa taaattttaa aggagtataa taaacagtgt tcataatatt
    12901 tttaatgaaa gaggtggtaa tatgccaaag attttagaaa atgtaaaaga agatatatta
    12961 aaagtatctc gagatatgat tttagaagaa gattactcga atattagcat aaggaaaata
    13021 gctcagaggt gtggtataag cgcaggtaca gtgtataatt actttaactc aaaacaagaa
    13081 ataatagaat acattacaaa atctgaatgg gatttattaa taaggcgaat tgaatactca
    13141 aataaaaata ctgaagatta catcaaaaaa ctagacatta tttttactga aataagaaat
    13201 tttataaaca aagttcataa tgtacaatac aatgactttt taaatacttt tgaaacagag
    13261 agattttttg aaatgaaaaa acacaaggat gactttcatg aacagctttc aaataaagta
    13321 tatgaagctt tagaaaaaga aagctttttt aataacgata aattagtatg caatatcata
    13381 ataaaaatgt ttttttcata ttcaacatat cttcatatag aatttgaaga tttaaaaccc
    13441 tatattgaaa aattaataca ttaaggtggt gtttaccttg aattctaata ctagtattaa
    13501 gaacaaggac agtaatccaa aaatattttt agtacttaca ctttatctat taggtatatt
    13561 tatgggagct attgatactg gaatagtatc accagcaaga acaattatac aaaatagcct
    13621 tggagtaaat gaaaaaacag gaatttggat gattaccata tacacattaa catatgcttc
    13681 tgtaattcct atctctggaa aattagcaga taaaatagga agaaaatatg tgtatctagt
    13741 tagtatattt ctatttggta gtggttcatt aatatgtgga ttatcatcac tattttccaa
    13801 cttctatatt ttactaatcg gtcgtgttat tcaagcaatt ggtggtggtg gaattatgcc
    13861 gattgctaca gcagaatttg gaactacctt cccagaaaat aaaagaggta tggctttagg
    13921 tttagttgga gcaacatatg gtattgccaa tattttaggt tcaagtattg gtagcacaat
    13981 tctaagcata tttggaactc aaaattggaa gtggctattt tttgtaaatc tcccaatctg
    14041 tttaatcata cttattggtg gagttttctg tattaaaaac aataaatctg aatctaaaga
    14101 aaaaatagat aagcttggta cattaatgtt ggtatgtata atcgtatcac tattatatgg
    14161 tcttatgaat atagactttt ttaattttaa aaattctata caagatatat cagtttatcc
    14221 atacttattg acatttattg tacttatacc tattttcata tttattgaaa atagagctaa
    14281 agaccctatt ttaagctttg aatatttttt aaatccaaga atattgataa tacttatttt
    14341 atctttaatt gttggtattg gaatgatggg tatggtattc gttccacaat atgctgaaaa
    14401 tgcattaaag ataaatgctg gttctggtgg atattttgta gctatactag gattatttgc
    14461 aggtgttgct gctcctttaa gcggaagact tattgataag tttggagcaa agaaaatact
    14521 attactagga ttttctgtgt ctatgatagg ttctctttat ctagtcttaa ttgctctaaa
    14581 aaccaataca gtattcagtg tatgtctaag tctaatgttt atgggattag gtatgggatt
    14641 tactatggga acacctctaa actacatgat gttatcaaat acaagattag aagaatctaa
    14701 ttcagcactt gcaacattat ccttgatacg ctcaattggt acttcaatta ctcccgctat
    14761 aatgattgga tttatagcac atgcaggatt atctgtacaa gataatatta tggacttagt
    14821 tggaaaaccc tcaacgccta aaatagttca acttgaagaa cttgaaaaca tgatagatga
    14881 cttaaaatca gaccctgaaa tggcaaaaaa tttaaaaaat gtctctattc caaatatgaa
    14941 tgatacttca aatataaata tggacatgac aggtggcaaa cttccaaaat acttacttga
    15001 taaagttcaa tcagcagata caaccaacat tacaaatata acaaaagaaa tatcaacaac
    15061 aatgtttgat gaaaaagttc catctataat ttctaaaata cagaaaaatg tacaaaaagg
    15121 aatagatgga acacaaagtg gaataaacgg tattgaagaa ggtgaaagta aactaaatag
    15181 tggtattaaa ggagttcaaa ctggtatcga caacatggta aaagctagag ctggtatcaa
    15241 tcaaggaata gatggtgtaa aaaaaggtat tgctggtatt gacaaaggta taaaagggat
    15301 ggaacaaggt cttaaaaagc aagataaagc tattgatgaa cttacaactg cttacaataa
    15361 aatacctact acagaaaaaa ttcctactaa taatgaaaat aactcaaatg aacaaaacca
    15421 agataatgcc agtaattctg aatcagacgc aactaataat gattccacag aaaataaaaa
    15481 taacaattcc aatgacaata aaccaaattt aaatgaacaa aaagaaagtt taaatgctca
    15541 aatacagaaa ttaaaaaaga caagaaatga attaaatgca aagttacaaa aaaataaagc
    15601 tcaaaagaat gaattaagta aaaaactaaa atcaatggaa tctcagaaga aagaactaca
    15661 aagtaagtta aataattcta taaaccaaaa gaaagacatg gaaaaaagcc ttgatacaat
    15721 gcaacagcaa aaaaaatcac tacaagcagt tttagaaaaa acacaggagg taaaaactga
    15781 aataccaaag gcttttgata aatcaaaatt ggattatata aattccatag aaaataatag
    15841 aacaaaaata gagaatacac tacaatctac tctaaactca ggatttaaac agatgtatat
    15901 aacagtattc tgtgtaaatc tactagcatt cgtaatatta ttgttctata aagaaaataa
    15961 aactagataa aagagtgtta tagtattata ttgtaaatct atcttattct taaatatttt
    16021 atcctaaaga ataaatgcat aaaaattttt gtaatggatt aatataaatt acaatataat
    16081 actatttttc tattaatctt ttttactatt aaaggaatca aaaggtatct tagcttatct
    16141 aaataaattt atacaatcta ttcatacaca cctttacatt tttataacaa ttaaacttat
    16201 tgttatatac aaatcaaaat aaaccatata ttttcaacta taatatgtta aaatcatatt
    16261 atgagcatat taatttaagc aaaatgtcat ttagacttta atttagtagt tttatattac
    16321 aattttttat atttttaatt ttaaatgtca tttagacatt atttataaaa agaaaggagt
    16381 gtattttgtg gatactttag gaaaaagaat tgcttattta agaaactcca aaaaacttac
    16441 tcagcgcaaa cttatggata ttttaaaatt tgaaaactta ggcaagtatg aaacaggaga
    16501 tagaaaacct aattgcgata tagtaatgtc aatagctgat tattttaatg ttacgactga
    16561 ctggcttctc tatggtaaag aaaaagtaaa ttccaataat agtgtaaaag aagataaaga
    16621 agattactta catattaata atgatgaaat gactatatta aatctatata gacaattaaa
    16681 cgaacgtgat aaaataaaaa tagaaggaat acttgaactt aagatatctg aatacaaaga
    16741 cttaaaaaag cattcctcta ataataatga agataaaatg gtttaaacat acataatttg
    16801 atacgatttt acatcatcta ttaactttct tttttggtag tatattacta aaatatggat
    16861 attggattat ttaaaaacaa gtatagtcta atttcaagca catttataat atttagatta
    16921 tcttatccat attttagttt acgtactttg aaaaatataa tacatttcta tgtataattt
    16981 atattcctaa gaaatgtatt gctcatgttt ttaattcttc caacatcttt ctatatacaa
    17041 ttgtacatcc ttcataattc ccctctttaa gaaggattga acatgtacta gaatatttag
    17101 tcaaaatatt taacctttcc atatttaagc tttttatatt actaagtgct gtaataaaat
    17161 catcaattgc tttacaacac tctataactc catctgaatc caatttacac acaagaatat
    17221 tcacctactt tatatactat ttattaatca tcttctgaat attctatatt aagcaattga
    17281 taaattgatg atttatattt tttacctgtt cttctcccat ttaaaatagc tgacaaatag
    17341 ttttcattaa cacctatttt cttcgctaat tctctttgag tcatatttaa ttcaataagc
    17401 ctttgcttga cttgtactcc caaaaaaggt atccattttc ttcgagcatc catttatcaa
    17461 cttcctttct aagtaattta tatttacttt tatattttag tttacgcacc ccctctattt
    17521 agtatatatt tttaatatgt acacatatta agtatataaa tttatttaat actaaataag
    17581 attttttgat tactttgtgc taaaattagg atgtaaattc gtatcattaa gttaattata
    17641 aagtcatttt gaccttaagt caatgatttt tatgtcattt tgacctttat tttaaaacta
    17701 tttatgtctt aaaaagtctt tttgacatta attgaatgga gagtgtttat ggatacttta
    17761 ggagaaagaa ttgtttattt gagaaaagca aaaaacctta aacaatatga actagaagaa
    17821 atgttgggct gtgacaactt gagtaaattt gagagaaaca ttagaaaacc aaattatgaa
    17881 atattaaaat ctatatctga gatatttaat gtttcagtag actggctatt aaatggagat
    17941 aatctatcac ataaatcaga tttaatttgc gattcctcct caaactatcc acttaatagc
    18001 ataaactcta atgaaataaa acttttaaac aactttagaa aattaaatga ttatgacaaa
    18061 gccaaaatag aaggtatgat tgaattaaaa cttcatgaat atgaaaaaga taagaattta
    18121 aaaaaaactg agtataataa aactaaagat gagaaaatag ataaataata tttatgttgc
    18181 ttttgatacg attttacatc atttctttgt tctaatattt ttatttcatt tattttcttt
    18241 tttataattt tatgataaaa taattagtat attttgcttt acttgaatgt aattatttat
    18301 acaaaagtca aacataatat aaatgtagta aatttttagt ttcaagtaat atctcgttat
    18361 tataactaaa tatttattaa aattaggagg ataaaatggg cttaagagac aaattcgcgc
    18421 aatcatttgc tagatcaaaa actatgagtg gccctgagaa aaaggctaat gaaataatgg
    18481 gtaaattgct tcttaagaaa gctatattac ctatcgtttt aatgttcgtg ataataatcg
    18541 ctggagctat gcttaaaatc aattcttggg ttacacttgg cataaattta gttattgctg
    18601 ttggtgcttt cttctacata agaaattcta gtaaaaagta tcagaacttt aaaccttatg
    18661 ttggcaattt gattagttta gagaaaaaag gtaaaaaaga gtacgttgct attataaaac
    18721 aaggtaagtt accagttaag ttacaaattg cttatggtgg tgaagacctt gaacatgtta
    18781 agaaaaatca aatggttcag ataagttata acccagatgc taaaatagct attttggtta
    18841 atagacaata atttaataaa aaaaggagtt gtcttaaaat tgattttttc taatcaaatt
    18901 taagctcaac tcctttttga atttttatat attattttta ttactttttt taattaatat
    18961 tttaaaatat taaatccttc tcaataaaat agggtactat ctacaatact actttatcat
    19021 ttcccaacaa tatataatct ggtgctactg ctacgttcat gttatacacc gttttgtaac
    19081 atacctttta tatcagtaac atcttcctta atttcctcta catctgtttt cattattccc
    19141 atttgaacaa gtatattctt atttatttct tgttgttgtg tagataattc tataaaattt
    19201 tctacagttt ttttatacat gtctctatct tcttttttct cttgcatagt atttttaaat
    19261 aatagagcac atagtatgcc gattgcccct agactactca attcggttat taatttatcc
    19321 attatagcct cctattgtcc aattttttta taattataac tttaattttt gttacattct
    19381 tacatcatgc aatattatat tttcaggatt atcaatttaa tcttttgtat tttaaattgt
    19441 aggtgtaatt tatagattga ataaataata aatatatata caatttctaa tataacaaaa
    19501 aataagtaca aggcttactt attaaagtta agaccttgta ctttacataa aaaaaataac
    19561 taatacatag ttattctaaa tttactattc aactggtatt tctaattctt tacatctaat
    19621 tctaacttgc tctctaatta ctgctggtac ttcttctatt gtttttttgc ctcttaaaat
    19681 taaagctaca tatacttcta ccattccact ctcacctcca gattttctta cactaaaagt
    19741 gcttatatta cttgcttcat tgacagaact ttgacttaac aacatctcat atatttccgc
    19801 atttgctata aaattatttg ttatatcatc atcttgcttt acttgaccta tacttatgtc
    19861 tgagatatct ttattctgca tttctacttt tctaccttgt ttgatttgtt ctattttatt
    19921 tttatcgaat ttaaacaatt ttcacacctc cattttaagc ttgtggctcg ttgttttcag
    19981 catcatatct aaaaatcata gatggacgtt ttatagctgt ccatttatct cctttttcta
    20041 ctatgatttt aggctgagca ctttttatgt tggcttcttc taattcatag atttcttggt
    20101 aacttgagtc tgattttttg atttcaacta gtttcatgtc tttgaataag tcagatttat
    20161 ttatttttac ttgaacttta gttttattta ttaattgata tatagggtct ccaagattta
    20221 aatcttcttc aagccctcta tctagtgtaa ttgtaatatc ttgttcatta gatgttgtat
    20281 taactacctt gtacattcta ttacctatca taacataaga atctttaatt atagaatttc
    20341 cagtactctc tttaaaaata aataaagatg catataaatc atcaccttta caataagctc
    20401 taaatagtat cttattctct cctattttaa ttttatctgg tggtacttca aatgatattt
    20461 tttcagtagt taaatcactt acagatttta cactttcacc atttataagc atttctattc
    20521 tacttatatc tttattaggg tcttgtattt ttatcttaat tgatgaaatt gatttttcag
    20581 taatttctat agcagcattt gtcgttccta cttctgatat aatatataat gtattgtctg
    20641 ttgcaagtac atcctttact gtatttacat cttcagaaat aggtactata gtaaattctt
    20701 ttaaaaattc tactggttgt tcaattttat atacatccct attttttcca gtaacccata
    20761 ctgaattatc atttttaagc accaatatat ggtcacttcc ataagatttt atttctctta
    20821 tgtctgttaa tgcttttgta aagaatttta taatagcatt ttcattatcg cttcctaacc
    20881 ctaaagctcc cttatcatta tatccttgta caaataattc attacctgta gttactacta
    20941 atgtatagtt tttaccacaa tgtacttctt tacaactaga tacagttgta attctttgta
    21001 attcagtaac tggattattg tgacctatac ctaattggta ttcagagttt ttaccaatag
    21061 accaaagact atcatcagat tttataaagt aagtaaagtt atctccacat gaaacatgct
    21121 ttacatctga tacattaatc tgcacaaatt catctacttg atttatagat aaatcttgca
    21181 ataattctcc atggtagttt gtaccacatc catacattgt tccatcatta agtaatataa
    21241 taatatgagt cttagaaata gatacttctt ttatattttc atatggaagt tcagtataaa
    21301 ggtctccttt gtacaaattt cctaatacta aaccataatc tatgtctttt gtggtaggta
    21361 taactatctt attatttaga agtataaagt tatgtctgtt tttaatagat gtcaaatctc
    21421 ccattacaaa gttcatatgc ttataattaa atattctatt atcattattt ctactatcgt
    21481 atctatttcc aacacctaat tgtccatagt tatttaatcc acaaatatat atatcattag
    21541 tatcttttat tgctatattt gcatattcta aaggaagtat tttctttact cttgtattgg
    21601 tttttataaa tgtatctctt tttgttacat caccaacacc taattgccca caatcattaa
    21661 aacctgtacc atataagtct ccattatcgc ttacataatg tccacatcta taattcattc
    21721 caatgtcctt tgcctttgat gctatttttt taatcttctc tggagtctca cttcctgtac
    21781 ctgaaccatt actacattta cctgcagtat atacatcccc ttcacttgta agtaaaagta
    21841 ctgcattatt tctgtttgga gctactttta ctacatttga aattggaatt tcagaaaatg
    21901 aactttgatt actgttacta tttagaccta aacaataatc agtatttaaa cctgtactat
    21961 atgcagtatt atagattgtt attatataag tatttatttc atttggtata acttctttta
    22021 cattttccat acactttata aaactgtact ggtcagtagt atttcccata cctaattgtg
    22081 aattattatt gtatccacaa caatatgcaa tgtttgtatc ctttacaatg aatgttgttg
    22141 tatctgagca gtacacatct cttacattag ttatattgtt tacagtaaat gtcaatacgt
    22201 ctggatggtt gctttcgctt cctaagccca gttgcccatg agtgttttct ccacatgaat
    22261 ataatgtgtt atcatctttg attgcatgtg agtgggtagt ccctaaaaca acatctctta
    22321 cattttgtat atttactttg gtaaatgtgt ttctatttac tatatcacct aatcccagtt
    22381 gtcctttggt atttaatcct gtggagtata gtgctccatc atttctaatt gcaaatgttg
    22441 tgttaccatc tatacttgtt gatattttct ttatattatc aaggtttatc tgagtgaact
    22501 tatttctatt tattatgtca cctaatccca gttgtccaga actattattt cctgtggcat
    22561 aggctgttcc atcatttttt actataaaca ttgtatttct tgatgttgta atttctttta
    22621 tatcatccat aaatataaat gagtttgatt gttcagttat atttgtgaat tttcttattg
    22681 gttgattgtt atattctcct atacctagtt tgttaaattg atttgttcct gttacatata
    22741 tattgttgtt tttatctact actactacag tgttattttt tacaattata tcttttatgt
    22801 cttttaatcc tgtatcataa ctacttacac catctagatt tgttatattt ccaaattctc
    22861 cattattagc aactccatgt ccatatagtt tagaactgct agaagttata ataaaaagac
    22921 ttcccaaatt tgaatattca gaactaatag tagtgtaact tttatatcca gtagcagaag
    22981 aaccaaatgt ttttggatat ccagtaacat atgtactacc ttttttaaag tataatatat
    23041 tatttgatgt tcctattact ttttctattc cattaaaagc gtttacttgt gtaaagtaag
    23101 tattataata agaactcgta gtttcaataa aacttccata tcttgaatag tcatttatac
    23161 ttggattgct ctttgatgta tctggatatc tatgctgtcc tgctaaataa acaaatccac
    23221 ttttgtcaat tattgcacaa ccataattaa aaggaaaaac attaactatt ttaggtaaat
    23281 cacttagatt gctagaacta gtagacaatg taactgttct atacttagat actaatgttt
    23341 tatttgtgct actactattg cctgtaccta attgatagta actattatat ccagatacat
    23401 ataattttcc ttcactattt atcatatata cagaacgata atatgttgct atcttttcta
    23461 taccatttat attttgctta tctgggtaat tagaagttct ttctatatta ctattagcac
    23521 tataacccca cccatatact tcttttgaat gatttagtgc tataatatat tcactttcta
    23581 cacaaaactc ttttacattc tctatttcta tttttgtaaa tatatttcta ttaacttcat
    23641 cttttaaccc taatatccca taattattta aaccacatga atataatgtt ccattattct
    23701 taagtacaaa agttgagttt ccatttccct ttatatccaa aacattatct atatccacct
    23761 tagtcataac tgacctgtta acagtatctc ccagtcccaa ctgtccataa ttatttaaac
    23821 cacaagcata taacgtacca tcattcataa caataaacat attattatct gttaactcta
    23881 tcttcttata atcctgaaaa ttatcactta actttacatt taaaaattca ctattatcct
    23941 ttgtaacata caaataatca tcattaacca ataaacctga ataattatct aaatttgaag
    24001 attgtacctt tgaaaactca tacagaaaag ttgtatgaaa aaatgaacca agttgacctg
    24061 ccagattaca gccagataca aatatttctt ttgaaccatt tattaaaaaa ttaaattgag
    24121 aaccacattt aatatctttt atattttcta cattaacctt aacaaaagta tttctggatg
    24181 ctacatcttt attggcattg gctagttgac cataattgtt ttgtcctgta ctaaatagtg
    24241 tattatcgta ttttaatatc atagtatgat tatttccaca agaagcatac ttaacattat
    24301 ttatactaga aagagtaaat acaattgaat tattattatt tcctgtacca agctgaccaa
    24361 ctccattata gcctgtagta tacatagttc catcattctt aataagaatt gtatgactac
    24421 taccacacgc tatctgtttt acattgtcca taccttctat tttattaaaa acacttttat
    24481 ttaaagtact attaattccc aactgcccat ttgaatttaa tccacatgca tgtgctgtcc
    24541 catccatttt tatgataaat acagattggt tataagttat tacatccttt acactatcta
    24601 tatttacttt agtgaaagta gctctattgt tagtatcacc taatccaagt tgaccacttg
    24661 agtttaaacc tgctgaatat aatgttccat catttttaag tacaaaagta aagtcataac
    24721 cacatgcaac agtttttaca tcatatattg gtagcttagt aaattcataa tatactgtag
    24781 actcaattac acctaattga cctacattgc ttgttcctgc tccatatgca aatccatctt
    24841 tagttactgc tacactgtgt tttgaaccac aagatacata ttttacatta tcaattttta
    24901 ctttactaaa catccttctc tctgacgaat cttttccaag tcctagttga aaacctgtat
    24961 tatcgccaca agcatataaa ttaccatctg attttaaacc aaaagtacta ttacttatac
    25021 cagtaaaaaa ttccacaaaa tcataatcat tatatctttt atcaaaatca tcaatcaata
    25081 tgttcttatc attaaaataa gcaccacgtt gtaaaagttt attttgcttc attattagta
    25141 ctacctcctt tatttatctt atttcatatg aatatttact tagagttata tctttttgtt
    25201 cttttaaata agtattacta gattttgtct caacaaagtt attatccata tcatgtatat
    25261 atctaactct atttgcacta aatggtaata ctacatctct aaaaatcaca ttaccaattt
    25321 cacctgttat gcattttcta tttaaatcta acttaagccc ttctatagct actatgttat
    25381 ttccatttgt taatgtatca taccaataac cagcctcatc tacagttacc tctgattcta
    25441 attctaggta tattaatata tctaacactt tttcagataa tttgttatag ctatttttta
    25501 atactgatat atcagtttgt atttgaccac ttataacatc atcaaaagat atgttttcta
    25561 tttttttaac tacctcattt atggctcctg ataaatcttt ggaatctgta gttaatatat
    25621 ttacatcacc aatgtttact tttatttctt ttatattttt atcgaactta tcatctaaat
    25681 cttgaatatc cttttgagtt acaaaaacca atgtcgggtc tacttctaat gtaacatttg
    25741 aagtattgga caattgtaaa atcattttta caaccaaatc tttaatactg ccatcttcag
    25801 cacgtggctt atacgtctct ggatacttac ctatagctat tatattattc tcattatcca
    25861 gaacagcagc ttctcttatc ataaatccac caactgttcc tggtaaaata gtctctataa
    25921 ctatccaatt aggatttttt tcatcaattc ttagagaatt tatatttcct tcccaaacta
    25981 cattctttaa agcagtttgt tcctctgttg gctcataata ttctccatta ctatctccaa
    26041 cttgaaactt ggttagtcca acaagttctc ctagtgcagt tgcatttgct attttttctc
    26101 taccaatttt ggttaatatt atataaaatt tttcttccaa ttataccacc tccgatttag
    26161 gataaactac tacattttct acacctgtat catttgcaat agctatatta atcttacaat
    26221 tattttcaat acatttaatg cttaaaggat aaacctttat ttcttctcta cttaacattc
    26281 cagctccaca gtttacaaca gcactgcatt ttataattgg ttcaaagtat ggatgaactt
    26341 ttacctcttc actacatacc atacctccac cacaatagac tatactttta tctagtatta
    26401 ttggttctaa atagtgtaat aagtgagcag gttttactct ttcaatcata tcgctacaat
    26461 ctaaaagagt tttatagtca cagttatttg ctataaaact caatacgaat gtaaattcat
    26521 cactataaac ttttatatct gtttctgatt ttgtatatgc ctcacatata ctttttataa
    26581 cttcaatagt actagtacct ctgcttctca ttttagcttt tatattgcta cgtcttgtgt
    26641 caaaatcaag ttcttttttt tcaatgcaga gtatatcttc ccacatatct aatccccatg
    26701 tcgctgtatc aacaaataat tggttgaagg tatcatcaat atcttcttta agaatattta
    26761 attctgtatc gtatgcacct tgtatctctt ctacaatgta atttctatca aatgatggta
    26821 gtttatcaat cagcttcatt gattttccac ctcactaaaa ttaacagttg ttacactagg
    26881 tattttatct tcattaatag ttatattgtc tgtacttcca tttataagta ggttgcttaa
    26941 atcatgtaca ccagcagtat ttataagtat tcccatgact tttgtataga ttatctctcc
    27001 tctaatatct ctaaagtatg tatttatact ttctaggaaa gattctttga cattatccaa
    27061 tgtatatcca tcttctagtt tcattactgc acttatattt atttctattg gtaatggcgt
    27121 cacaactgtt atagttggtc caataggctt ctcttcatct atatgttgtt gacatctttc
    27181 aatcgtttct gtatcaacag cttgattatt tttcccaaat atcaagactt taactgttcc
    27241 tggaccatcc catcttggat aaaccttaac attatagact ccatctactt ccaaagccca
    27301 ttcttcataa tgagctttat ttccacttgt agcttgattt ctttggattt tataaaatct
    27361 ttcctttagc tcttcatctg tctctatatc tgtaccacct tcaaaacttc ttgtgttagt
    27421 aatctttgtt actccagata tattatcaac tagtttaaat tcacaatttg taggtaaatt
    27481 atatctctta ccaacttcca gagcttgaac tggactattg tcaccttcct cactaccaat
    27541 agttacatct tttattacta caaagagtaa atctctatat gatattactg tgccattatt
    27601 tattacagtt ccattctctc caataaattc aacttctcca tttgactctg tacccaactt
    27661 tctatataca ccaaattcat tgactctttt atcaagaaac tggttatatg tgtcttgtat
    27721 aaaagccatt ttatgtatct ttgaaagttc tagatatatc tttgaaagtt ctagattgtt
    27781 tccagatatc atgttgttta gaaaagaacc ttctccttta taaatatcaa gattaatatt
    27841 ttcaagagtt ctatttttta ttacttcata tgtctggtca ctatacattt atttccacct
    27901 ccccatagat agtggatact tttacatttg cactcaatat gtctctgtta aagttagcac
    27961 ttcttacact tacttctaat atatatggat ttattagaag ggcctctttt atgaatctac
    28021 tagcttcact ttctgtaaga ccttttgtat atttttgtcc tattagttct gaaagctctg
    28081 tcccatattc taaagagtat atctcatgtt catatctatt tgtctttata cacttgtata
    28141 tccaaacttt taaggcttct tttttctcaa ttattttaaa atcacctttt tctaaaatag
    28201 gttcatcttt ttcaaaatcc catgccactt cacgaaagat tggcaattct tctgttttag
    28261 gtaagatata atcctctggg acacctataa aaggaaatat tgtactcatt ataagctcac
    28321 caacttactt acaatagcaa atttttcgcc tattctaaac attattacca tatccccaga
    28381 ttcaaaagta tctataaatg gattttttac ttcatgtttg tgttcttgat ttgtttctgt
    28441 atcaaatgtt tctatctgtc tatcaagcat ccaactatct atcaaaatat cttctttttc
    28501 taatatgatg ttatttgtct ctatctttaa atctggtaat ttacttttaa tttttccaat
    28561 aaaaaaagaa ggttgattat gatgctttcc ttcttctctt attattccta taaattcatt
    28621 tattggatta gccattatat caccatcctt ttataatact ctccttgctg tattaaaatc
    28681 ttttctacta cttaacttac ttattttaac tacatcacct ttttgtggag catgtaaaaa
    28741 ttctccatta cctatatata gtccaacatg gctgactgga ttatgaaaaa atactaaatc
    28801 tcctgcttga agattttttt gttctacttt cttgcctttt ttagattgtt gatttgatgt
    28861 tcttggcaaa ctaacattaa cttttttaaa acaatagacc attaaaccag aacagtcaaa
    28921 actacttggt ccatttccac cccatttata tggtttacct agatgttttt ttgcttctga
    28981 tattactatt ttagctttat cagatacatt accagaataa ccaccgataa taatttttcc
    29041 ttttcttctt ccaaatttac tagcttcttc aacatttcca aataaaatat ctatgtggta
    29101 tgttccattc ttttctatag ttattgcagg tcctacgtca tttactttat agactccatc
    29161 acgaccagaa actcctgtaa ttacctgtat ttcatctcca tagtttaata gaggatgttt
    29221 atttaaaaac tcttttgtat aataagtttg ctcatattta ccaaccatag gagcagcgca
    29281 agttttttta gatgggtcaa gttttttctt tctacaatct gtatctccac cttcttcttt
    29341 tctaggacag taagctgtaa attctgctgt aaactctttt cctcctgcat aaccttctcc
    29401 tcctaaatta ctttcttcct taggttcatc ctgtcctgct gacttttcat ccataagatt
    29461 ttgaaaatta agttcaagtt caatttgata ctctccattt tgccaggtat gtttgtctgt
    29521 atctatataa aatagtccta caagctttgt ataagaatct ttgactttta cccctctacc
    29581 agttatacaa cttacatctc cataaccttt aagagaacag cttttttcta tcccattaaa
    29641 ctcgctatca atatctacat cttgattttc ttgttgctga attacttttt gcattattac
    29701 atttacttcc ttaaaaattt cattatctat tttttcgcta atcttacttc catactggtc
    29761 taccactatt actttatttt ttacattttc catactctcc gaaaaggtgg tatttataat
    29821 attaaatccc tcttcaaaca taacacttaa tgtaacagtt cctttttcaa taacattaaa
    29881 cttatctaaa tttgcctcta tcatatactt tttctttgtc tttttacttg cctctgtata
    29941 tgcactcatt attgtgtcat aaccatttac tcctataaac atctttgtat acttgacatt
    30001 ggtctttgct attgttccaa ctgaaatcct attttcagca aatacttgct ttgctatgtc
    30061 ttcaactaac ttatctttaa aattgtatga cacttcactt tgcataagta gaaatcccat
    30121 atctttagat acaaaactaa tttcattact gcttgaatct ttagacctat taattatcat
    30181 tcctctaaaa agttctttat catctacgta gaaacaaact gtactagcta ttggtatatc
    30241 tatctgttgg aaatttacat caaatgatga ttgtattatt gaaaactcta gtgtccttga
    30301 tggagattta taatcacctg accatgatac cttgtctact atgtcagtta tgtcatatat
    30361 acttccgttt tttatgtgta cccaaatctt aataataaaa aatcacctgc cttttcattt
    30421 aattctatca gcagttattt ataacttatt atctataata gttattgttt tggagttact
    30481 tttggtattt ttattctttt atactctttt aagtctaatg taaaatacac atctcgagtc
    30541 ccatctcgtt cttcatagct aaagccctca attatgacct ccatatttat atttgtttct
    30601 gtaattgtaa atcttagtat aaaaccttcc ttcatccatt tttcaatctt atttacacaa
    30661 tcatatggtg atggaaaacc tgtatagtca cagaaagtat agtctttatt tggaaaaaaa
    30721 cttgatattg aaatgctttt aagagctaca ccaccaaaag ttgctatttc acctattttg
    30781 agtatactag aagagtttac agtagctttt ccattaatac taaaggaaga tggaaatact
    30841 ggaaatctaa atctatcttc ggcttgtcta agccacattt ccattataat acacctccca
    30901 attgtgccat ttttatactt gaaactaatt ttgatgtaac tttttctata tcagcttctt
    30961 ctctaatcac tattgtatca gctaacttag ctatgtttat atttccacca ttttttctgc
    31021 ttctatattg atttgcttct tgtttagtta aaaccatttc accttcatgg agtctggttt
    31081 gatagtcatt ataaggaaca tagttcaatc caaatgcatt attacctttc ttacttgaat
    31141 aagctttacc agaatcacca gcctttgttc cagcatatgg attatctttg taattttttt
    31201 tactcttttc cactagattt aaaactgttc ctgtgatgct tccatttttt atcttattaa
    31261 tcatagtttg ccaccatttg catatatctt taactatttt acatacttta tctaatatgt
    31321 taaaaaaagc tcccaatatt ggctctataa ttttccatcc agtttccaac agaggtccta
    31381 aggtctccca tacagttttc caaataacac ccagtgtctc tataaaattg tttatttgag
    31441 gtgcatattc acctaaaaaa gtaaaaattc ttgtgataat aggactaaca gcttcaacta
    31501 caggcccgat taattggaat gctgtagtta ctattgtacc aaatatactt attaatcctt
    31561 gtgcaattgg tgatttattg tttatactat ctagtaaatt atttactaag tttactactg
    31621 gaagtaatga atctattaat gctgtaaaat cgatattttg taatagtgta cttcctgcgt
    31681 taacaattgc ttttggtgca ttccctatca ttgttgctgc atgattttca aaacgttctt
    31741 gcttattttc aaccatcatt ttacgctttt cagcctcatt agaaattcga tattgagtag
    31801 aatcagaaaa ctcttttcca ttttttacac ttctagattg catctggtca tatttgttgc
    31861 caataattat cttaccattc attacattgc ctattttacc agccattttt tcagataagc
    31921 cagctaaatt gcctaatcca ctttctataa aagtttttat tttctttagt ccttgaccta
    31981 aaatatcatc aaaaggttta acaatactct tcaaaccatt gttaatgctc gtttgagctc
    32041 ctgatattat acctggtatt gtattactca tttctttagc taatcccatc tgctttacac
    32101 ttataccttc caatgcttca tcaaaagttt tataattttc tcctaccaga gtattaagag
    32161 attccatatt tccttttgct gcacttaaga aagctgctga tacatcttgt tcactacttg
    32221 tattcatatt taaagctcta acatctacca tagcctgagt tatatctttt tcttttttac
    32281 caccagtaat attactaatc attttagctt tagttcccat tgcaacaaca tcttcagggt
    32341 caaaaggtgt cttatctgct atatctaaca aatcttcata ataattatca acatctcttt
    32401 gattaacttt tccagtattt cttttcatta cactttctag aacaactttc tgattttgtt
    32461 cctgaccaag taagtcaaca ccctttttca cagcgacacc tatagtagca ccatttgtca
    32521 aatcagatat cttccctttt attgaaccaa gtattccact tgccatatcc tttacagcta
    32581 ttgcacctct ccatacctta cctgcaaaca atctcaattt tggaaatact ttacttataa
    32641 tgctacttgc catatctttt atagctatta caccactcca aaaagtattt ttaaacaaca
    32701 ttaacttagg caaaattcta cccatagcac tgcttaccat atctttaaga ttaatacttc
    32761 cttgataagg acgtttctct actcgtttta aatttcccaa gatactactt atcactctct
    32821 tagtcatatc ttttgctttt attacaatct tccaaacctt gccaccaatc ttttttaaat
    32881 ttccaagtaa tttattttta gttttttcta tttcatcact tttagcttta aatattaata
    32941 taatcataat atttgaattt aactcatttt tcttttgaat caacttatta aaataatcaa
    33001 taatcatagc tatagttatt gctagtctca taatacttcc atttaaactt ccaataactc
    33061 ctgaaacagc atttatgcta gaacttaatt ttgtcatagt tgaacttaca ctgctagcgg
    33121 tagtctgaac ttttcttaac gaagaattta aactgtttac tctactactt gcacttccaa
    33181 tagaattttt tatgctacta gccatcacat tagtagaaag tgaaacagcc acagttgctc
    33241 tcctaaaatt atcagttact gatataattt gattcatttt tggtgtgtaa ttatctgtaa
    33301 gatacatatt tataccttct tctcttacat ttcccattac ataccacctc ctgtcaaagg
    33361 acacactcca tatccatgtt tcattttttc aacttcttcc tcaatttcta aggcgaaaaa
    33421 agcttcaata agctttaatt cgcctttatc cattgcataa aaaagggacg gccttatacc
    33481 ttttttcttc caataatagt acattattgt agtcttggta tccgtcccta ttagtttttt
    33541 acctcttcta tcactgcatt tttaccataa cccataacat cttgaagtat tctatataag
    33601 ttggtaattt cacctggtag taataatttt cttgccaatt cttttggtgt tggagcctta
    33661 aatttatcca ttagctcctt atttttaaat aaaagctttc catctaaatc acaaacacct
    33721 tctataattg taagcatctg catctccggt aagtctatat ccgttttcat attttcatca
    33781 attttaagac aagtattttg tatctcttca tctttactta ttgttaaagc tctacacatt
    33841 actttaaatt cctgcccaaa tatagttgat aatctcttaa gttcaactat agtgctcggt
    33901 ctttctaagt tttctgtatc tgaatttaaa agtaaatcta ctatatttat attttttgat
    33961 aatccatttt cactcattat tatttgctcc tttatcaatc aaattcaatc aactaacttt
    34021 tttacttatt aactatctga atttattaag tatatactta ctaaatatca ttataaaacc
    34081 aaatataaaa ctaaattata tcaagaaaat catactcagt aaatgtgaaa ggtgcttcta
    34141 tctctccttt tactccaacc tcccaatcag ctaaagttaa atcatcaaac gctatatttt
    34201 ttactgctat tctttctgct ccataagaat ctgggtcatt taatttagat atagcaacaa
    34261 atctaggttc agaacctctc tttatctttt ctccaattaa cttatgcatt cttgaactaa
    34321 catggtatag agttattgaa ccttttcctt tatatcccat atactttgta tcagtaccca
    34381 tttgacctgc tattataata tcctcttttg taaattccat ctttgcttga aacttcttta
    34441 cttctgctac tttgtttcca tcaagccaaa gttctcccca agtaccactc attacatttc
    34501 tagcttccat atttgccata ttaataatcc tcctatattt ctattgataa atctatatct
    34561 tccatagcat caagtacttt tatttttgct tttaaaaata ctttagaacc tgtgttagct
    34621 tcttttattt cttgtaatgt catataagat aaatctactc cttttgattt taaatacgat
    34681 ttttgtgctt caaaatctat ttcaacagta gaatcagatt ctataagtgc agatttttct
    34741 aattcttcta aataactttt tatagctact atcaataaac atttgttgtc ataactgtta
    34801 gtaacctttc ctatatagtc atctattatc acctttctta tatcactatg tataatatct
    34861 aaagtgtcaa ctatttttat tttctggaac atttctcctt tttctgctgt taattcagtt
    34921 aaagaattta ctcctctagc aattcttata gctcctgctt ctttaataag tataagctct
    34981 cctttattaa cccttgattc tgcatcaact ttagtcatct taggtatatc gactacatca
    35041 ctaagcttag tataggttac tgattgactt aaaggtgtac ctgctataag cccagctacc
    35101 ctacttgtaa actcatcaac actgtatttc ttttctccaa ctaacacatc ttctgtagta
    35161 aaattaatta tcccttcatg atttcctaca acttttccta atatagcttt aaccttaacc
    35221 ttatctatat ctctaagttt aattatccaa ttttttatag cagtcttatc agcttctact
    35281 gcttttggca tacatagata attaaattcc ttagtctcta ggaagtctaa tgcagtttga
    35341 atatctgctt ctccttctat tacataaact aataacttat ttggagtgtt aacatttccc
    35401 atcaaagcta aatttatata ttctttattt tcagcagata aatcaactgg tatatcctct
    35461 ttttcatgta tctcgttaag acctaatgcc ttagcatctt taagcaccat tgcaattatt
    35521 cctctagctg aacgttcttt aacagttgta gctagctcct taaatgatat gttgatactt
    35581 ggtaatccta tagccatact atcactctcc taaatttaaa ttgatttctt ccatattttc
    35641 atatactaca tcttcttcat atacactatc cagatagttt agtgtaaccg aaaaattcaa
    35701 tgcataaatt gactcttctt ttttaatact ttgttctagc tttgttatat ttaattttct
    35761 gtctgttacc tttatatttc tgttaaatag cttatttaat tcatctgaaa tttcatacat
    35821 tctaatactc tttgactgtg gttttggtaa gtattttata gagataacaa tatctttgtt
    35881 attcgtattt aacattatag gtgtacaaat aactgataat atacttacaa aaaaacaaga
    35941 ctcttcagag ccttgcacac tttcatcatc aataaaaata ctttcagtaa agtttttttt
    36001 gagaatctca ataattgttt ctaatatttc cttgtattta agcaaataat caccacacta
    36061 tcactaaata ttcttgctta atctgataat cttactataa atgatataag tcatttttaa
    36121 atatacatct catttattcc tgtcaagtat cttctatatt tctaggtaat attattcttt
    36181 tcaatctatc acctccttca atatggattt ctttcacaat aacattatct cacatatttt
    36241 attacctatt gttgcaatgt tgtatataaa gtgttgtaaa attgtcctat tttttataat
    36301 atctcactca atttaactat catctttttc tttaagttgt agcaggatgt tctatctaag
    36361 tgtagtttca tagaaatata cgtcatattg ttttttgtct tactattata aaaaagatta
    36421 aaaaattcca tttctatatc atttagacat gttagagcat tttctatctt ctctttttct
    36481 atttctatat cttctttttc tatttttaat tttcttaatc gttcctccct tttcaacacc
    36541 tcattttcta cagaggaact tatattatat gtgttactag tcttttctgt atataccatt
    36601 gctccacatc cagagtattc attttcatat ctttttatat ctaaattaat gttctttatc
    36661 tttatatcca aatacttgta attatgtaat ctttcatctg tttctttaaa taatatatct
    36721 tttttgtttt ccatagtatt tctccttttt atatatttat tgttagcttc aaatttacaa
    36781 caatcttttt agtactaatt tttttattaa tcttaataat tttaagaaca ttttgttcta
    36841 taactgtata aaaaaaactt cttctatatt ttgttctaaa atgctagaaa tcttcttggc
    36901 cataagaagc ccaggatttt ttatacctct ttctatttga gatatataat catttgtaat
    36961 tccagccttt ctagcaagtt gaatttgtgt cattcctttg cattttctat aatatttcaa
    37021 attattttta aacattgttt tatacctcca ttactattaa gaatattttg ttctcctata
    37081 tttagattat atagaattat ttgttcttta tcaatagatt ttagaaaaaa atattctttt
    37141 atactttact agttttattt tttagaacaa tttgttataa tctatacata aggtggtgtt
    37201 ataatgtttg ccaaaagatt aagagaactt agaaaggaat ttggattgac tcaaagagaa
    37261 cttggagaaa aagtaggtgt ttcccaaaga gtcttaggat actatgaaac agaaaacaga
    37321 tttcctgatg aacacatttt aaataaattg gctgatgtat ttgacgtatc agttgattac
    37381 cttcttggaa gaaccctagt taaggaaaat attgatacag tagctgcaca tagaaaaaat
    37441 ccacatgaag agttacctga agaagcacaa gaacaactta atgattatat agaattttta
    37501 ctaaataaat ataaaaaaaa ataaaccata tgatgagcag tctatttttc tgctctttta
    37561 atataactca aaggcaaaca tacattctat tttaggggga tttttatgaa taatttggat
    37621 aagctttttg aattagcttc tcaagaagag ataataattc attataccac ttatattgca
    37681 ggtgatttag aaggactata tataaataag cacggtatga aaatcatatc attactcagt
    37741 aatttaaaac aaaatacaaa aaaattgaca tccatcttag ctgaagaact tggacatcat
    37801 tttactagtc ttggatacta tgtatcctct tataatgatt attatacaaa aatcattata
    37861 gataagtgtg aaaataaagc cttaaaatgg gcttgtgagt tcttaattac tgaagaggat
    37921 ataataggca taattaattc tggcgtcact tgcgtttatg aaatggcaga tatacttaat
    37981 gtggaaatta atttttttca aaaaagatta gaatttttat cattaaaaaa acagtcttta
    38041 caacttggaa ataataaata tttaatatta actaatttgc cgtatttcta catatttgat
    38101 ccaatttcat aataaaaata gtagtaattt taactggctt accagtaaaa tctatatatt
    38161 tattttaaca aattttggtt tctataaatt caatattaat atataataat gatatcatat
    38221 tatttaaaat tctaaaaaca aatatatgct tttgttaaga aaggttgttt gatgaatgta
    38281 taaagaaaag ttgtttgata attattttaa gttcttagca ttattttttt ggccaataat
    38341 gtggtataag tggatagtaa tttcaaatgg tactcttgaa aatatgttat ttaccaccta
    38401 cgcaattatt gcaattgttt tcatcatttt atattcagta tctatgataa aatataaaga
    38461 cattacacaa atagatttct tttacaggat aagtactcta cttgctttta tatttacact
    38521 ttttagcttc ttaatatacc caaagagttt atttttcttg tatttaaaga ttatttttac
    38581 tggaatatac ctttattatt caatagtaaa aacacttaaa tttaaagatg acgagggtgt
    38641 agtgggtatt atgagctcac ttttattaat tgtaataact ttattctact aaatttaatt
    38701 ctatttgact taatatggct ttaaatatta gacatctaca ttgttttctg atattattta
    38761 agatggtagt tttatattaa taatgaaata cactatgaag gagttaacta ttatggaaaa
    38821 aaaagtttta gcaacagttg gagaaaaaga gataactaat attgacattg aaaatgcatt
    38881 aaaatcatta gacccttatc aagctatgca atttaaaact gaagaaggaa aaaaacactt
    38941 actaaatgat ttagtaaatc aagaattatt cttcttagat gctaaggaag aaaaattaga
    39001 tgaagaagaa atatttaagt tagaaatgaa aaagatagaa gaaaatgtat taaagcaatt
    39061 tgctataaat aaagttttat ctagtgttaa tgtaacagaa gatgaaaaag taaaattctt
    39121 tgaagctaat aagagttctt tctctaaacc agaaagtgca actgctaaac atatattagt
    39181 agatagtgat gaaaaagcta aagaaatact tgctcaaata aaatcagaag aaatatcttt
    39241 tgaagatgca gctcttaaac attcttcttg cccatctaaa gatatgggtg gtgatttagg
    39301 aacattcggt agaggacaaa tggttcctga atttgaagaa gctgtattct ctatggctaa
    39361 aggtgaagta agtgagccag ttaaaactca atttggatat catataataa aattagaaga
    39421 ccttcaagaa agtacagagt ctacatttga tgaagttaag gctgaggttg aaaaaagttt
    39481 attatatcaa aaacaaaatg aagtttatgg aaataagata aacgctctta atgctaagta
    39541 tggaaacctt gtaaaataca acgattaatc ataaagtaat gtataaaaaa gctgtctttt
    39601 cacaatattt attataaaag acagcttttt atattaaagt ttaaatatcc agcttaatat
    39661 tatcattctt ttattgcaaa gaactcagct taaaagttta aataagattt ttaattatca
    39721 ttagctaaat ttttatatcc acgtattatc tcataacaat aacctattac atctcttctt
    39781 tttattatcc caataaatgt gtcttggtca tctataacag gaatgaagtt ttgatttaaa
    39841 gattttataa ctaaatcttc aatatctgcg ttgatggaaa caggagaatt atccattttt
    39901 ctattaatat ctgtcactgg aacatcttcc aatcccttta agtccagatt taaatcgttt
    39961 tttaatgtcc ataaaaaatc accttctgtt atagttccaa catatttacc atccttactt
    40021 attattggaa ttgcagagta tttgtgatat tccatttttt ctagagcttg ccttatagtg
    40081 tagtcttcat atatatatgc tacttcactt tttggtgtta gaaagaataa tatgttcatt
    40141 acactaccca ccgttactga aaacttataa atattattca atatttataa tgttactttt
    40201 ttgcagtaac tttctccttt cttattttct aagtattctt aatactatac gctgtaacaa
    40261 gcgtttttct tttggtcatt ttaatcttat tatgctttat taatattttt atatggtcta
    40321 tcagtatcac ttattctctt tttagaaaat tcactaaaaa ttaattgact taaacttagc
    40381 cataataatt ttactctaca ctattaattt taacatattt atctcattat taatgatttt
    40441 attttaataa ttttaattta ttttgatatt aattttattt acaaaaactg aaaaaaccgc
    40501 taaatgatta gcggcttatc tctcatatta ctagaacact aatatatatg aatttttaat
    40561 tataatctaa ctacgttagc agcttgagga cctttagctc catctactac ttcgaactca
    40621 acgctttgtc cttcttctaa tgttttgtat ccatctccag ttatagctga gaaatgtacg
    40681 aaaacatctc cttcaccttc tacagatatg aatccaaatc ctttttcgtt gttaaaccat
    40741 ttaactacac cagttttcat taataaatcc tcctaaaaaa acacaaatat ttagctactc
    40801 ttttctgtaa ccttattact actctatcat atatagctat gtttgtcaat tattattatt
    40861 tttatacatt aataatcaat ttttttactt tataatttta aatcattatt atcttttaca
    40921 ctttattttt ctttatattt tttcaataat ttatttttat tatatggaat cttatggact
    40981 tatcactcca acctaaatcc catggcacca acattctatc cgtattatgg caagttacca
    41041 aaggatatcc tcttgagtct aatcctgtca ctgtcgaaac atgtgttatt ctgcctttct
    41101 tctcataacc aacaaaatct cctggacgta aattataagc ttctttgtat acttcttcat
    41161 aagaaccttt agcaattaat gaacctcttc cactatacag tgcataattt ttaaaagctt
    41221 gtgcatttac ccatgctttt gtacctgctc tttcactata attccaaatt gagttctttt
    41281 tgaaccttcc actttcaaac attatctgtg atgcaaagtt tgcacaatct ccaccttctg
    41341 gattataatc cctatagttt ggattaaatt tcataccatg ttcttcatca gctgcggctc
    41401 cacagtattt atgtgcataa tctattgcct ttttttgctc atctgtaagc tgtaactcta
    41461 caccatcttg ttgaccaata tagtttctta tatcatcaga ttttatattt tctaaattta
    41521 aagagtctgc aaaagggtct gtataccact ctttagttat gacatattga ttatctataa
    41581 tttttacatt tagataatga tatgtaccta ttctaaaggc attttctttg tccttttgat
    41641 tttcatatga atacttatat tcagtcgata ctgaacagat tataccatag aggtcttttt
    41701 ctttttcctt tattttttta atcttaaccc ttgtctttat atctttaaat tttacgcctt
    41761 gcttactaga ccagttttct aaatacttca tcttttttac ttcattttca taagcccaaa
    41821 gaccaaattt tttatctgtc tcataaagac cttttaaaat attttcattt ttctctaata
    41881 ttgccttatt tctgtagtca aataagtttt caagcaatag tttatattgg tcttttacat
    41941 catcaccttc aatatttgca gattccatga ctttttcttc catatttttc atacttaaat
    42001 cattgattaa aaatacacct gctgtagtag ctaaagataa aaatacaaat gccattatac
    42061 ctttgatgta cttattctta tttttcagta ttttcaaagc tacacctccc aaatagtaca
    42121 ccttacaaat caaattacaa agaatattct gtcacataca ataattttca tacttaataa
    42181 ttctatattt tattatgtcc aatattaaaa attaattgta tcaatacact gtttttttta
    42241 caatttttta ttttataatc tacttttttc ttttttttat agtaatatat atgtatataa
    42301 atattttggt atcattataa ttaatacata ctaatggagg gttttttatg caaaaaaaag
    42361 tcgcagcaat taatgactta tctggaatag gaaaatgctc attatcagtt gctataccta
    42421 tactttcagc attaaaggtt caatgttgtc catttccaac agccatactt tcaagtcaaa
    42481 ctggttatcc tgaatttact tttttagact ttactgatga aatggtaaaa tattcaaatg
    42541 tttggaaaaa tttaaaagtc cactttgata gtatatacag tggttttttg ggttcaaagc
    42601 atcaaattga gatagtggct aattttataa atgattatcc caatgctttt attgtagttg
    42661 accctgtgat gggtgataat ggagttatgt atccaatatt cacagaagag atgagacaag
    42721 aaattaaaga attagttaaa cattcagatt tgactactcc taatttaaca gaagcttgtt
    42781 tcttaactgg aaatgattat actaaaagtg attataatag agatgaactt atatatattg
    42841 caaaatctgt atctgattta ggacctagca aagtcgttat tactggtata ttagaagatg
    42901 aaaacatact aaacttagct tatgatagag ataatgacca tgtattcttt acatcagtta
    42961 aatacaataa ttgttcttat agcggaactg gagatatatt cacatctata ctttgtggta
    43021 tgttagtaaa taaacatgat ttaggagtag ctgttaatac tgcaacagat tttatatata
    43081 aaactataaa ttacacatct caatttgata ctgatagaaa tgatggagtt atgtttgaaa
    43141 actttttatc agatttaact aatatataaa atcaaaaaaa ttatccattt tataaatacc
    43201 tatgaatcat aaaatttagg tatttacaaa atggatatta tttactaaac tattggtatt
    43261 tcaattgtta ccatagcacc accagttttt atagagtttt caatatgtaa aatcccatta
    43321 tgtttttgta caatattatt tacaatataa agacccattc cataatgaga tttagagttt
    43381 ctacttaaat ctcctgtata aaattgtcct gtagcctttg acaaatctgc tttagaaaaa
    43441 ccacttccac aatctgtaat cacaaatttt aagtatttat tacttactga tacacttatg
    43501 tatagtttac tctggcttgg tgaataatct atagcatttg aaattacatt cataatagct
    43561 ctaaataaca attctttatc tatagttata ctttcaggca aattaccttg tttagaaaat
    43621 tcaacattca agttttgtgt acgagctaat gcttctattt gaatcaagat atcttctata
    43681 aattcactta cattaattac ttctttattt aatatataac cagtctctgt ttttgatatc
    43741 tctattagtg tattaatata tttttctatt tgggtggcac cttttgctat atattccatg
    43801 tattctgata actctggatt ttcatttatt tcaattagta agtcagtatt tccatgtata
    43861 atagtcaatg gtgtttttat atcatgtgct aatgcagata tctgttcctt acgattctct
    43921 tctaacatcc actgtttttc taaagaatct tttaaagcta acttcatttt atccatagaa
    43981 aaaagaacat tattgatttc acggatttta ctagattcta taacaaaatc taaatcctgc
    44041 tgttctattt tttctgtagt attttttaaa agttccattt cagcatttaa ttttttgcca
    44101 aataattttg atagtataat aatttcaata agaaatatta tactaaaaat aatcattcct
    44161 aatagttctg gctttggtaa atatgtcctt aaagttggag aaacaaattc tgctactata
    44221 ctataacgta ttatacaaac ttcatttttt ctggacaatt tgatatagtt ttttgatgac
    44281 gtaatagtcc ttctttcaaa tcctcgcatc aaatcccata cttcttttga ctcattctta
    44341 ttgaaagttc ctgaaattac tttgccattt aaagtataca ctccatactc acataaatct
    44401 ggaattaaat ctttagttac ttgtttactt gaaataatct tatctttatt ttcatagatt
    44461 tgtttttcca cataattagc aggtaatatt atatttaatg ataataatat aggaaatgat
    44521 aatatcaata tagatactaa gacaacggtt atagcaaaga ataaagatga atatcttaca
    44581 aaaacagttc taagtgttac aatcttttta ttattaaact ttttacctac aagtatcctc
    44641 accacatcct ccaaacttta attagtttat agttaattat aaactagctt ttgatttgat
    44701 tattttttat ttttatcact aaactatatt ctaacataat aatataagta aatagtaact
    44761 tttttatttt tattcttcag actttttacc ctcccattta gaaaaccaaa tacataaaat
    44821 tataaatgct aaaatggtta caaatccaca tactaatcct attgattgat atcctttaat
    44881 tgattcgact ttaatatatt caattgtctt agaacttgaa aaagatgacc atatacttat
    44941 aaatctaaca ccccatacac aaggaatata aggccaaatt ctagcaccta atccagttag
    45001 caacactgct gagagtaaag tttctactat acccactcca attgaggctc cttttccaaa
    45061 tcttaaactt aagaataaat gtaatatata tacaaataaa ttactcccaa ctaaaatcat
    45121 aattgaaatc atataaaaat ctaatgtaaa ataaacctca ttagaaatac tagatacacc
    45181 aaatttaaaa cctaatacag atactagtgt tgctccaaaa ccaaggcaga ttaatattat
    45241 atacttactt ataagtgtaa gatattttgg attagatgat gttaacatat gtttataact
    45301 tcctgaataa tactcttgtt caatacataa tgaacacata atacttgata ataaaggaaa
    45361 agctattgct ataacttgta aatatgcagc tatctttgat atatcatcag cacttgaata
    45421 cttataatat cctaagcaca atcccatgcc tattaaagca atgcaaaagt gcattagtat
    45481 tataaaagtt cgctttaatt ttattaaatc agaacaaaaa attcttacta gttgtgtcat
    45541 attacttcac ctctctatta ttgaaccaag catttgtagc taaagaaagt aatataaata
    45601 aaacaataga tattaacact cctggcaaaa ttacattact atttaaaaac tcacttcctt
    45661 ctggtacagg aagtccattt ggtagaatat gcaatacagg agccattaat cgtggagtaa
    45721 ttgaatatgg aaatgcatac cacatttctg tagtcgaaaa aacggcaact ccaattatag
    45781 taaaaaacat gtttattata attgtaataa acataccaaa ttttgatgcc aaaaacatac
    45841 aaagaggaat ctgccacata aataataaaa ctaataatat ggttccaata atattttgac
    45901 ttactgaaat aacttcctta tataacatcc caacaagaaa tatacctatc ataaaaataa
    45961 ttgaggttat aaaacaacat ataatgcaat aaagtatttt tccagtccaa acatcttttt
    46021 tttcaattgg caatgataaa attccacgat acttcttttt ttcatctttt tgtactatta
    46081 gagaagaaat caatgttaat acacctggaa gaaacatagt gtaccaccaa ttataaacac
    46141 cattttgtcc tccaccaagt aaaaatgtaa tgattataga aaatattggg gctatccata
    46201 tcaatctaat tccaaaagtt cttttcattt tttgaaattc tgctctaact aatttttcca
    46261 tattaatttc ctctctttct attttcagct acaactttca taaaaagttc ttctaaattt
    46321 tgctcttttg atacttctcc ttgatatcct agtactccat tagaaattat tccaatttca
    46381 tctacaactt gttcaacctc agacaagata tggcttgata aaataactgt aatcccttgc
    46441 tttgggaaag aacgaatcaa ttctcttagt tcttcaatac ctatagggtc aagaccattt
    46501 gtgggttcat ctaagattaa aagctttggg tgatttaata atgcaatagc aataccaaga
    46561 cgttgcttca ttcctagaga aaattgacct gaacgctttt taaaagtatc tcttaggtcg
    46621 acaatcttta aaacttcttc aatgcgagaa tcaggaagac caagtaaagt agtatgaact
    46681 tttaaatttt ctcttgctgt taaattctca tatatagcag gagactcaat aagagaacca
    46741 atatttgata aatcctttct agtccatcta tgcccctcaa acattatttt tcctgaagtt
    46801 ggatttaaaa ttccagttat catttttaat aaagtggatt taccagctcc gtttggtcct
    46861 agtaatccat aaatagaatt atgtttaatt gctattgaaa tattatcaac tacaacctca
    46921 tccttaaact ttttagaaac tccttttacc tccaaaatat aattactcat aattttcatc
    46981 ctttcttttg acaaacttat ttacaagaat cattctaaat cataaatata aggattttat
    47041 aagaattaaa aaatcacaaa aaaagatgtg ttaaaaaaca catctttttt tatcttaact
    47101 ctattaattt cccattgtag tatatttcta cttcttcaat ccaaatacta ttatcttctt
    47161 cttggatgac atttttaata atattattta tagtgtatat tatattttgc tcattcaaat
    47221 aatcatcttt ccaagaaact ctactttttt catctggttc tatcaagttt attttaacaa
    47281 gattatcttt ttccttaact tccacttcca tgtctaaacc attaaaatac tcctttgata
    47341 atgtgtctaa gattaatcgt agtttatctt taagtgtact ttcttcatca atctgtaagt
    47401 actttactat cttaccatcc tttgaaatta tctctatggg tattttagta gtattcttag
    47461 aattaatcat tttactagtt gtttcttctc tcacatcatc atccttcttt acaactgctg
    47521 actctttaga atcaactagc tcaactgcgc tgatgctata atccatacat gctgtactca
    47581 ataaagtagt agcaattatt aaaaaactta ctgctatttt attcataagt atccctctcc
    47641 taattctctt tcgatactta ttataccata gtatagatta tatttttata cttttaaatc
    47701 aatttataaa ttattatagt aaattattta caattctaat ctatttgaat ttatttttat
    47761 agtatattct ttctctaaat tcgacagatt tttattcaaa agccctttta tttccctcgt
    47821 atttctatac ttgttgctat gttcttcact atgttcataa tcatatgaat cattgtcata
    47881 ttcttcatca ttattaaatt cttcgattac ttcttttgac tttatatcac aattaaattt
    47941 atacttattt actggtatat caagtcttac cttagaattt ggaacttcta tatccagata
    48001 cttagcaatt ggcatattag aatataagtt aaattcatta tcataatttg agtgtctacc
    48061 tattttctcc tttatgttta cattttcagg tatatattct tctatattat tgataaatac
    48121 accttcatcc tttgaagata tatccaatga ctctgattct atatttacat ttttaacacc
    48181 taaaattgac tttgttgata gatgaagatt gctattagat attaagttta agttttctaa
    48241 tctatttact ttattttctg ttatagctct gctaaaacct ccagaagaag ttttatatgt
    48301 tatattattt gaatctacat catcagatat aaataagtac gaacttatac ttgatgcatt
    48361 tatatctaca ttatttggta catatattct aatttctcta taatcacgtg aaaacatact
    48421 atttatagat gtatttaata agtggtcgaa acttctaatc tttttaattt tattttcaga
    48481 ttttctttcg ccttttacaa ctaaagtctt atcttgtagg gttacactgt atttgtaaaa
    48541 ttcattattc cctcttgttg tcacacgcac atcttcattt gaactttttc ttatcataac
    48601 atttatattg tcaacagata catctaactt gtcaatattt actttttctt gataaagttt
    48661 gttttctttg tttaattcag cttccttttc taaaccaaag tttattaagc ttggcataac
    48721 taaaatccct gaccatgttg tccctattat acctattacc aataataccg cagcaaatat
    48781 ggcaagtttc ttattcatat ttatcttctc ctttcttatt ttctatatct ttaaggtcct
    48841 tatatatcgc ctcaaaattt atactatcat cattatattc atcagtttct tttatgcttt
    48901 cttcttctct attgtagtaa tcattattat atgaatcttc attaatgtct ttattcaaat
    48961 cttcatcatt taaagtagct ttttttcttt tttccatctt ttcatttgcc tttatataaa
    49021 tattttttct ctttatccaa tgtatataat tatttagtaa ttgtttacct agttttatgg
    49081 caaatagtaa aagttgccat gcaagtatct caatccctac aaatgctatg gttgcgaaaa
    49141 tacaaaacat cataacatct ggaaccattg ctataaattt aatcacaaat ggaattaata
    49201 taacaaaagc aattaatgaa catactaatg caatagtaac agatacaata gcacatacaa
    49261 acgcaaatgc tggaacaatt agaaataaag ataacactac taataatccc tttataactt
    49321 gtctagataa tccccctaca ccttcttcta tacttggtgt aagtttatca tttatatttt
    49381 cttttgattt attgtacttt tccttagctt catctttcaa gatagagtaa tcctttttta
    49441 tatttgattt aaacctacta aatttaccat ttaatatatc tgtactcatt atttttccat
    49501 ctatattttc ttttgattta ctatactttt ctttagcttc atcttttaag atagaataac
    49561 cctttttcat atctgattta aatttactaa acttatcatt taaaacatct gtatttatta
    49621 ttttttcctc ttgaatattt ttttctttgg tctgtaggat aagttcttta gctatagatt
    49681 ttggtgaacc aagtgatgat attatctcca tatcactctt tccttctata agaccatcta
    49741 caaaatattc ttcataatct ctcaatatat cattaacttc gctctcagaa aaatcttttt
    49801 ttagataatc ctttaaaatt tcaagaaact cagttttatt caagctcatt acctccctta
    49861 tcttcactta ttaaaatttc aacagccttt acaaattctc tccactcttc catcagattg
    49921 gataaatttt cttttcctag tgaagttatt ctatagtatt ttctagcagg accttcatta
    49981 gattctagta tatatgtttc gaaatacaaa tcttttgtaa gtcttcttag aataggatat
    50041 attgttcctt catttacatc tattacttta gaaatgttat gtactatctc atatccatac
    50101 atatctttct tagatatgag agcaagtaca caaatttcta agacaccctt tctaaattgt
    50161 gtgttcatat actccatcct ttctttaaat acacagtatt gtgttttaca aggtactatg
    50221 ttaaaacttc ttatatcccc ataatagcac agtactatgt tctgcacaat agttattttt
    50281 aaatattatt gttgattaaa tccttctata aatgtataat actctaatca gatatatttt
    50341 atgaaagtgg tgataagttg gctaaaatga aagatgataa aacaatatta atcttaactg
    50401 ctcaatttgg agctggacat ataagtgctg caaaagcagt caaggaatct attattgaaa
    50461 aatacagtaa ctataatgtt gttatacaaa actttataaa tgcaagtatt cccatgatga
    50521 ataagcctat ggtaaaactt tatgaaaaca atacaaaata tactcctgga ttatataatt
    50581 actattatta ctttaagaaa tcgtttgatt caagacatga tttttctcat aaattatata
    50641 cacctaaact ttctgagtat attgctgata taaatccaga tttgattatc tctacatttc
    50701 cactagctgc tgcttgtgta aataacttta agataaaaaa tcctgatata aatataccta
    50761 cacttacagt tataacagat gttgtagata gtatggaatg ggtttttgaa aatacagact
    50821 tgtattttgt tccttctcct gaaataaaaa atagattttt tcagaaagga ataaatccag
    50881 attccataaa ggttactgga gttcctgtag ataagagatt tcaaattgaa agtaaagaaa
    50941 tatgttgtga taaatataga ctattgcttc taggtggagg aagaggtcta tttgatatag
    51001 atgaggactt tatgcattgg atagatgaat ttattgaaga acatagtgat tctatagaaa
    51061 ttacaatagt tactggtaaa aacaaaaaat tatacgacaa tctaactcat aaaaaacctc
    51121 taaaaaatat taaagtactt ggatttgtaa acgacatgta taatctaata agagagtgtg
    51181 acctaatgct aactaagcct ggaggagcaa ctatatttga agctattcaa tcacaaactc
    51241 cagtacttgt aaaaatgcca aaagttggac aagaaattga aaatgctaaa tttataatag
    51301 ataaggggct tggcatgatt tatagtgatg acctagacct aaaaaacata ttttataggt
    51361 tagtatcaaa tgaatttgat tctataataa actttatgaa aaaaaattta gaggaattta
    51421 aaacagtcat tcatccagag aaaattgctg attatatatc agaattaata gataaacatt
    51481 acagttaaat tgtgctatta caaaatttta aacaaaaaat taaaggcaat caagtatgct
    51541 tttacacttg agaatttact catagtgctt aataatacat gattgccttt atcatatcaa
    51601 aatcaaattg ttatcttagt atatattttt cttgtactgc atatatagtt gttgtatttc
    51661 ttccatactt ctctttaact ctatttgtaa atctgatgca gcctgataat ctttattttc
    51721 tacagcttct ctcactctag taaatagcga ctctctagtt aaagtatcct tcataatatt
    51781 gaactttaaa tctgatattg agttccaaac tacttcatca agtgcatcca tattttcttt
    51841 tgtgtgtatc ttgacaatac ttcttatttt ttgaatccct tcttctatta ttctagtttt
    51901 taatttcttt tgccacttat ctatagctcc aatcttaaag gattctatta tactatcagt
    51961 aaatacatca ccttgtttta aagattttag ttttgaagca tatatttcta agtttttcat
    52021 attttcataa actgtagctg gtgggattcc aaatcttgca tttctttctt ccaaactgta
    52081 atgttcaaat acatcatttt catctctata tgctctatct ttttctaaat agaaactttc
    52141 ttcacctaca tttttagata attctttttc aagttctttt gtactaagac cactcttagc
    52201 tgctgctttt ataccatcca acattgtttg ataacaccct gctattacta aatatgtgtt
    52261 agatagaggg cttggtgatc tcaactcaaa tcttacagtc tttggatttt tcatatctct
    52321 tattaatcca acaagcactg acctatttct tgatggaatc tcataactat gacctaaaga
    52381 tgtaactata catacaggag cttcaaatcc aggaactaat ctattaaatc catcattaga
    52441 agctgttaca attgggttta aaacttcata gttgtaaaga agtcccataa gagccccata
    52501 tcccagttca cttagataat cttcttttaa atcttttgga gcaaatagat tttttatact
    52561 tccatccttt aacttcgcac ttactcctac atgtgtgtgt ccaccacttc ctgctactcc
    52621 atgaattggt tttgctttaa atgtaacttc tagtccatgt gatgtaaata catcttctat
    52681 aacatctctt actaataact cattatctgc tgcttgtaat ggtgtagaaa acttccaaga
    52741 aacctctaat tgctccatag catggtttgt tcttccatct atactaatag aactttgtat
    52801 tcctccaacc tctttgtgag ccatttcagg gcttacacct agtttttgaa gtataattaa
    52861 acttttctct aaacaagttc ttataatacc atgagttctt ttccagtatt gctcttttag
    52921 gctttgtgat acatataatt tctctaggtc agctttatct tcaggagtat taacccagaa
    52981 ctcaagctct gtagctgctg ttaacattat ttcctctata tcatctactg aatctattcc
    53041 tatgttattt attacatgtg gatattctct aaatatttca tacattgatt ttttaaaata
    53101 cttatctgct ttttgaagta ctcctctaga acatactttt ttattatcat gtattaaaaa
    53161 tgcaggtatc tttaatgttc caacaggtag acctacttct tcgtctatat attccatatt
    53221 ataatctaca taccaatgac aacttttatc cggcattaaa tctacttttg cattatttaa
    53281 tgtagctatg ttataaagct caacacttga accatcagtc tgtatagctg attccaaaaa
    53341 cttatctatg tcatccaaaa ataattctac aggaatcttt tcatctgttg cattgcctcc
    53401 taaatcaacc cccattaagg aaacaaatct tatattttta ttgcttttta ggatttctct
    53461 taattcttca ttagtatgtt tatctttctc tattacgtat aatagactat ccatttttcc
    53521 actctcccat aatttttatg taaattttat tttgttaaat acaagataaa tttcattttc
    53581 cttacattta tgaatttttc ttgcaaatta ttcgtgtttt attcgtgttt ttatttatat
    53641 tattatatat caagtacaaa aagttcgcaa tattttttat tggaaaaaat attatacata
    53701 caatagttta acatttttat aaatatgggg tatactaaaa taaaagtatt tttatttgaa
    53761 aatttaattt tatttataat ataatctata gtaaaagaaa taataaaaaa atttaggaga
    53821 taaactttat ggaatacata attttcgatt tagaatttaa tcaaggattt gataaaaaat
    53881 tcaataaaac tatatccaat gaaaagtgtc cttttgaaat tatacaaata ggagcaatta
    53941 aattggattc taaattcaat ataatagata catttaatag ctatgtaaag cctacgattt
    54001 ataaagaaat acatcctttt attagtcgta tgactaatat taaagattct gattttaatg
    54061 attcgcctac tttccctgaa gtttacaaca attttataaa atttatatca tcacaagacc
    54121 ctatattatg tgtctgggga gctggagatt taaaggaatt atacaggaat atcaactacc
    54181 acaaactacc atcaaattcc ttacctaaat cttatattaa tatacagcaa catgcatcta
    54241 aatattttaa taatccagca ggaaaaagca ttggattaca aaatgctatt tctatattgg
    54301 aacttgatga aaaaatgtct tatcacaatg ctttaaatga tgcatattat actgctaaag
    54361 tttttattaa gatatacaat ccaagtatag taccagatat atatctttat acaagtatca
    54421 aacctaaaac tataagatat tccaataaaa aaagagttga ttatgataag ttatttgatg
    54481 agtttaggaa aattttgaat cgtgaattga ctaaagatga gaaaaaaatc attaacttag
    54541 cttataacat gggaaaaaca aatcaattta tattagaaga tgctaaacaa agaaaaaaca
    54601 aataaagttt acttaggtta aaaataggca tgtagattaa ataattagtt agctttaaat
    54661 ttatatctac agcccaattt ttatcctaat taatctttat tttatttcta actcaactgg
    54721 acaatggtct gaacctaata cttcagtgtg tatatctgca cttatcaatc tatcttctaa
    54781 ttttttggat gcacaaaaat aatctattct ccatcctgca ttattttttc ttgcattaaa
    54841 tctatatgac caccaactat agacaccttc tttatcagga ttaaaatatc tatatgtgtc
    54901 tataaaccca ctatctaata atttagaaaa cttctctctt tcttctttag tgaaacctgc
    54961 atttttcata ttatttttag gattttttaa atctatttct ttatgtgcaa cgttcatatc
    55021 tccacacaca attacaggct tatgattatc tagttttgtt aaatagtcta taaagtcgtc
    55081 ttcccatcta gttctatatt ctagtctttt taattcagat tgagaatttg gtgtatacac
    55141 tgtaacaaag taaaaatctt caaactctag agttatcact ctaccctctt tgtcatgttc
    55201 ttctatattt attccataca ttacttttaa aggctctttt tttgtaaata tagcagtacc
    55261 tgaataaccc tttctttcag cataattcca atattgaaaa tatcctggca aatccaactc
    55321 tatttgtcct tcttgtaatt tagtttcttg taagcaaaat acatctgcat cgacttcttt
    55381 gaaaaagtcc aaaaatcctt tcccagcaca agctcttatt ccattaacat tccatgatat
    55441 aaatctcata ctatactcct catctaaaca gtaaatttct tgttattctt catttgcttt
    55501 tattttaaca ataatatact ataatttcat ctaaaattac tatttactta atacctaaaa
    55561 atatatgttt taatcaattt tcaacttttt tgttagctct tcaggactca ttgaagaaac
    55621 atacatgttt gttccaagtt caaatcctcc aaaattgtat tttcttggga ttatgtgcat
    55681 atgaacatta aaatacgatt ttgtttcaat ctttgttgga tgagtgtgaa tacataagtt
    55741 aaatggcata tatccattga tattgtacaa tttcttaaac aacttttcaa atattgtaga
    55801 aagttccttt atattattat catttaactc accaaacttt attttatctt taaatattat
    55861 tcttacttct ccactatact tggttgcata tggtataatc actaaaaaag cttctccatt
    55921 ataaacaact cttctattta aacttatttc attttctatt aaatcatcat acaaagagct
    55981 tttattgctg tcataatact cctttgaaac taacagttca ttcgtaattt caggaggaat
    56041 aaaagacata gacaatattt gagcatgtgg atgcatcaaa gatgctcctg cctttcttaa
    56101 gaagtttttg aagatactaa catactccac tttatcatct ttggacaaat ctctaaatct
    56161 atttctatac ataaaaaaaa catcttcaaa ttctttttga ctcatgttat aaaaactacg
    56221 attatgttta ctgctctcta tcattacttc atgaacacca tatatgtctc ttgccatatc
    56281 atcaattata gggaacttat tgtagacaga ttttacaagc catccttctt caccttctat
    56341 ttcaaataat gcatcagttg cataagcttc atttcctttg caaaatggac attctttatc
    56401 gtattcatta gtttcttcat cttcatttgg tatatctgct gtatctaaag gtctttttaa
    56461 cctatcagta gcaaatataa caacatcatt ggtaattgga tctattctta attctttcat
    56521 agttaacacc tcttagttaa tagcctttaa tataattata tgatatttat cgtatctgtt
    56581 aaataaattt ataatatttt ttataatttt gcatatttat tattatatat tttgtctata
    56641 gctgaaagat tataactaaa aaattactat cagtgtatca gaatattatc ttaccataaa
    56701 ttaattcata aatacataat ttagtggcat aaacatgggt atttaactat aatttgttaa
    56761 aagtttattt taaaactata ttaatttttt ttgatgattt ttacccataa gtatgttatt
    56821 attatcttgt aaagatgtct tgtattcaaa catacaattt acataataca atatacgtat
    56881 ttaaattaaa tagggggtat taaaatgaat tattcaaaca gagttagtgc aatgcaagcc
    56941 tctccaatca gaaaacttgt tccatttgca caagcagcaa aagataaagg aatcaaagta
    57001 tatcacttaa acataggaca accagacata aaaactccta agggattttt tgatgctgtt
    57061 aaaaactttg atagcgaagt cttagaatat gctacatcag aaggtattcc agaattatta
    57121 gaagcacttc aaaattacta taaaacttac aatatgaatt ttgaaaaaga tgaattacta
    57181 gtaactaatg gaggtagtga agctttactt ttcactatga tggcagtttg tgacccagga
    57241 gataatctat tagttccaga gccattctac acaaactaca atggatttgg tcaatctgta
    57301 aacgtagaag ttaatgctgt tacaacaaaa gcagaaaacg gtttccacct tccatctaaa
    57361 gaagaaatac tgtctaaggt agatgataaa actaaggcta taattctttc taacccagga
    57421 aatccaactg gtgcaattta tacaaaagaa gaacttaata tcctagctga aatagctaaa
    57481 gaaaaagatt tatggataat agcagacgaa gtttatagag agtttgttta tgatgggctt
    57541 gagtatacaa gctgtggtaa cttagagggt gtacaggata gagttataat aatagacagt
    57601 gtttctaaga gatacagtgc ttgtggtgct agaattggtt ctatcgcttg taaaaataaa
    57661 ggtcttatag ctcaaatact taaattatgc caaggaagac tttgtgttcc tacattagag
    57721 caaataggag ctgttgaatt atataaaact cctgtttctt acttcaaaga agttaatgaa
    57781 gagtacaaaa aaagaagaga tgtattatac aatgaattaa tgaaggttga aggagttata
    57841 tgtaaaaaac caactggtgc tttctatata gttgctaaat taccagttga aaatgcagaa
    57901 gacttcacaa tttggatgtt aaaagaattt aacaaggata atgaaacagt tatggtttgc
    57961 cctgctgaag gattctatgc tactccaggt ttaggacgtg atgaaataag attagcttac
    58021 atcctaaatg aaaaagacct tcatagagct gctacattat taaaagaagg tttagagcaa
    58081 tatgtagctt tacaaaaata attttttaaa attaatttat ataaatttaa tgataaaaaa
    58141 tatccccttt tcagatatta tttgaaaagg ggatattttt tatagagatt ataaaaaagc
    58201 acatcaagaa aatttaagat atacttttta gattgtattt agatttataa ttatatagct
    58261 aaattcataa caaaaagtta atcttaatac tattaaatat aaaaattttt gtattttttc
    58321 tatctaaatt cttctttgtt caatatatat tgaagagtat ttattgcttc taaatatttt
    58381 tttctgtctt cttcagttaa tttagaaagt ttttctccta aaccatcact taacttatcc
    58441 ataaaatcag ttgctatctt atctccctct tcagtaatat caattagata ttttcttcta
    58501 tcaactaaat ctctttttct tgttacatac ttcttatcag ttaaatcatc aaccatacta
    58561 gttaaactgc ctttttctat atttaactta gagcataaat cagtcatact tattactcca
    58621 taatttttta tgaaaactaa tgctcttaat tgtgttttat ttacattata atctggtgca
    58681 aattttttta ggtcttctaa atacaggcta gaataaatct taggaaatgt ttttactaaa
    58741 aaacttatgg tatcttttac tatatagttc atataatcac ctcggttgtt ttaaaattta
    58801 ttaaattatc taaataactt tatttcagtt tacattaaaa atattgcaag tacaatagtt
    58861 tttgctgaat gtttaaattt aattagtaat cttatcattt tttattttta tttatattaa
    58921 atactattta tatagctatt ttattaaatt catggtatag taagtaaaga agaactcttc
    58981 acagcggtga agagaagacg ctagcccatt aaaacggcta tcttatttat aaataagata
    59041 gccgttttta attatatttt atctgtataa ttctataccc ttaagtctac atctactttt
    59101 cctaagtctt ctttataatc ttttatagca ggttctacaa cttcatttac aaactctaca
    59161 acttgttctg gagctctacc tataaagttt tttgggtcca ttatagataa tatttcttct
    59221 ttgctcatct taaatgaatc atcattcatt ataagttcaa tcaaattatt atccttacct
    59281 tcatgtttta ctctataggc agctttcata gaatattctc ttattatttc atgtaattcc
    59341 tgtctatctc cacctctttt tacagcttcc ataagtattg tttctgtagc cataaaagga
    59401 agttcttcat ttacacgttt atttatcata ttttcatata ctactaaacc atcagttaca
    59461 tttatcccta tttcaagtat agcatctgct gccataaatg cttgaggtat tgccaatctc
    59521 ttattagctg agtcatctaa tgttctctct aaccattgag tagcttgtac cattgcaggg
    59581 cttatagact cagagattat atacttagat aaagatgcta ttctctcact tctcattggg
    59641 tttctcttat aagccattgc tgatgaacct atttgatttt tttcaaatgg ctcttctaat
    59701 tcttttaaac tttgtaaaag tcttatatca ttagtcattt tatgcatact ttgagctatg
    59761 cctgataata tgcttactac ttgataatct aactttctag tatatgtctg tccacttact
    59821 gcataagaag aattgtatcc catctttttg caaattttct tatctaactc ttttactttt
    59881 tcatggtctc cttcaaataa gcttaaaaaa cttgcttgag taccagtagt acctttaact
    59941 cctcttaact tcatattatc tattctatag tttaaatctt ccaaatcaag aattaaatct
    60001 tgagcccata aacaagctct ttttcctact gttgtaagtt gagcagcttg gaagtgtgta
    60061 aatccaagtg ctggcatatc tttgtactta agtgcaaatt cttttaaatt gtttattaaa
    60121 tttacaagct ttactcttag aagttttaaa gcttcattca tttgtataac atctgtattg
    60181 tctccaacat atgcagacgt tgcccctaaa tgtattattc ctttggcttt ttcacattgt
    60241 aacccataag cttttacatg agacattaca tcatgtctta cttctttttc tatttttcta
    60301 gcttcatcaa aatttatatt atctatatta gctcttagct catctaattg ttcttcagtt
    60361 atattgattc ctagctcatg ttcaccttct gcaagtgcaa cccataacct cctccatgta
    60421 gagaatttaa attgtggaga aaatatataa ctcatgtcct tgctacaata tctatctgta
    60481 agtgggtttg aataagtagt atatttatta tctatcatta tattagcacc ttccttaaat
    60541 cttttgtcgt atgattactg tgtacacatt agtacataaa taattatata taattttacg
    60601 aactataaca agactttttt attttttgtt catatttata tagtgttttt tatttattaa
    60661 tattttttat ttatatccaa attatccttt tcaattaagt aatccactat ttcactatca
    60721 acaaaattta atacatactt atatctaatt gcatagtatt tatcactcca tccaagctgg
    60781 ttttttacat cgctctcatc tgccccaagc cttaaactta ttgctgcaaa tgaatgtcta
    60841 aaatctcttg ctgaatattg agaaagccca gctaaatcta atgctttttt gactataagt
    60901 ctgacatttc tatctgttat agaattactc ttttgagttg taaaaataaa atcatcacta
    60961 ggtattatta cctctggaag cccagaataa ttcctgtaat cttctaaaag tttaaaaaag
    61021 tatggatgta atttaactac tctttctttt cttcccttac ctaatcttac atatgagtta
    61081 tcgttttcat ctaccataag gtctttccac tttaagctaa ctaattcatt taataaacac
    61141 ccagtagtaa ctagacagac tattattact ctatctctta tatttaattt tggtaggata
    61201 cctataagtt tatttatttc ttgtatactt agaacgtcat cttttgtttt tattcttgtt
    61261 actgttggtt tttctacata tctaaatgga tttatatcta tgtatccttc tttttttaag
    61321 aagttataaa aactatgtaa ataactatat atcttttcac aagttgattt cgcatattta
    61381 gtctgtatat aatctacaaa atttttacaa tcttcttttg tagcataaat caattccttc
    61441 ccttttaaaa actctttaaa cagtataacc tttgataaat aatcgtgttt tgtgtttgga
    61501 tttaattttg tagaaaaaac attaaaagtt tcatactcat aatcatctag tatttttgta
    61561 ctatacataa taactccttt ccttttcata aaataaaata actatacttt tactatacca
    61621 tatatttccc cctcaaatat accccttatt caagggatga cttttaagtt tattttgtta
    61681 tattatgaag gttttatgaa aatgtcaatc ttccattgtg cactacacag tactatggta
    61741 ttataagtta gtaaaaggtg gcattttttt attaatatat gaataaaata tgctactata
    61801 aatttgtatt ggaggtattt tggtttggaa acatttagtt tgcttgaaat ttttaaggca
    61861 gtcattttag gaatagttca aggaataaca gaatggctac cagtaagtag tacagggcat
    61921 atgatattag ttgatgagtt tataaaattg aatttttcaa atacatttat aagtacattt
    61981 ttagttgtaa ttcaatttgg ttcaatatta gctgtacttg ttatattttt tagaaaatta
    62041 aacccttttg atagtgcaaa aaatattaag cagaaaaaag aaacagttcg tttatggctt
    62101 aaggttataa ttgcagttat accatctgga gttattggaa tactgtttga agatgatata
    62161 gatagattat tctttaattc aacagtagtt gctattgctc ttattgtcta tggtataata
    62221 atgatagggc ttgaaaagag aaataaaaga cctaagtata aagatttttc tcaagttaca
    62281 tataaattag ctctttgtat aggattattc caatgtctag ctcttatacc aggtacatct
    62341 aggtctggtt ctactataat aggtgcagta ttacttggta cttctagata tgtagcagca
    62401 gagttttcat tcttcttagc tatccctaca atgcttggag ctagtgcatt aaaacttcta
    62461 aaagctggat ttggatttac tggatttgaa tggcttattt taggtgttgg ttctgtggta
    62521 gcatttgttg tttcaattgt agttattaaa ttttttatgg actatatcaa aaaacatgac
    62581 ttcaaagtat ttggttatta tagaatagtc ctgggtatag tggttcttgc ttatttcttt
    62641 ctattataat gtattctaat ttaataacaa atgataagga gaaaagttat gagtgttaaa
    62701 aaagaaatat ttgattggat taagtcaata gctatggcta ttgtacttgc atttgtaatt
    62761 ctacaattta taagaccttc tattgtcagt ggagaatcaa tgtatcctac tttagatgat
    62821 aaagattacc taattttaaa taggatatca tacaaagttg gtaaacctga aaaaggcgat
    62881 attgtagttt ttaaaaccaa tttagttgat ggagaaacag gaaagaaaaa agacttaata
    62941 aaaagaatta tagctactga aggtgacaga ataaaaatat caaattctaa ggtgtatgta
    63001 aatggaaaat tattaaatga gccatatata cataataact atacttctgg agatatagat
    63061 actgttgttc caaaaggtaa aatatttgca atgggagata atagagaaaa tagtaatgat
    63121 agtagatttc ctgatgtagg tatgattgat gaggatgaaa ttcttggtaa ggttatggtg
    63181 agactattac ctcttgataa tattggaaaa gtagattaaa aaaaagagac tgaattggta
    63241 aaatttattt tacaaatctc agtctctttt tatttactta aattaaaaat attttttact
    63301 aaatatcttt tgattctgta ataagtctta ttatatcact tgcttcttca ttaaaagttg
    63361 ttactatact taagtagtct gttgctctac tcatagctaa ataaacctta tttaaatctc
    63421 ctacaaaatc atttacttga taatcttgct caatatcatt tatagtttga ttgtataaca
    63481 tttctaattc acatactatt actgctttat attctaaatt ctttattgca tatatatttg
    63541 ctattgtagt tcctaccttc ttacttatat ttgttaagtt atcttctgca catatataag
    63601 gaatttttgc ctcttctaat gcttttttta acatatactg gaaataaata gtttttccac
    63661 tttttaattt cttcttatta taaggataaa caatagcaac ttcggaataa tcaagacctt
    63721 ttttacttat taaatactca atttcccata ttacagaact tatttggtca tcaaggtcac
    63781 ttacttttat tatatcaaca gacttatttc cacctctaag tgctttagta taaaagaaag
    63841 tactaaattc tgtatttggt cttaattcgt tgatatatga gttagaatta tttgaaaatt
    63901 tatttgtaaa atctacaatc tctttggctt gtctataatt tttacttaag ataatcttat
    63961 catcaaattc tataccatta tataactttt taaatatatt taatctatta gagatattca
    64021 aagagttaca agaacacaca ttaaatataa attttgtttt atataaaaac tctcttataa
    64081 aatctatttc atactctaaa aagctttctg cttcatctat aaaaatagct ttaaacatat
    64141 ttttattttt tataatgttc tgtgcttgtt ttacaagatt attaaacgcc ttttcgtaat
    64201 cattttttaa catgttatag tctacaatta aattgaattt tttagctagt ttaaatataa
    64261 aagaactaaa tgtgtgaact tctaaattat tattatcttt atataacaac tctatcctct
    64321 ctctaagctc attgcgcaat tgttttgtat gtgtaaatat gattaattta tgatgtggat
    64381 atacttttgc taattttata gctctagaaa gcataattgc tgttttacct ataccagagc
    64441 caccttcaat aagtgtattc ccatatttaa tagaaataac atctttaatt tgaacttctt
    64501 ccatcatagt tgctgtatac ttatagtcat cattgtagaa tgaaattttt ttaaattttt
    64561 catttaaatg aagtttgtca tttattatat agtattctga acatacatct aataaaaata
    64621 aatttaagtt tatctcatca ttctcatcat taagatactc atccagcgaa cctttattca
    64681 ttatatcttg aagcttattc ttatctatta tattgttatt aacaaattct tcaaattcat
    64741 atgtttcctc aacttcaacg tatggcataa tgtaaacgta gttataactt atatttctat
    64801 tcttttgtcc catttttagt ttcaaaagtt catattcctc attcataact tcaagtaact
    64861 cttcttctaa aataaaaaat atatcttccg ttgtatccat aaattttata aataaaattt
    64921 ttccatcttt aacatacaac aaatcggtat ttattccttt aaaaggagta acttttggca
    64981 ctactttaac gtccttattg atattctcgt aaaatatttt ctcaaattct ttcaatttta
    65041 gggcgtctaa ctgagaattt atatttatgt attggctcac ttacattacc tccttctgtt
    65101 atacttaatt ataccatttt gaactatatt tttatatata ctttttatag gcaaatttag
    65161 taaataaatt caaaataaat acaaataaat acaaaacagc taaaaaaatt ttgcaataag
    65221 tacagatatt tattgttata gaatatttta tgtaaatagt aaaatgatga atttcataat
    65281 taatacttac aa
//
LOCUS       DAMKOJ010000012        60592 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000012 DAMKOJ010000000
VERSION     DAMKOJ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 60592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60592
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.013"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(49..900)
                     /locus_tag="PC592_000875"
     CDS             complement(49..900)
                     /locus_tag="PC592_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HDF4054883.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHYFEQGTKIKVSYSGGVFKSGDLILESLKKY
                     LNKARFD"
     gene            complement(1010..1924)
                     /gene="murQ"
                     /locus_tag="PC592_000876"
     CDS             complement(1010..1924)
                     /gene="murQ"
                     /locus_tag="PC592_000876"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDF4054884.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAVEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVEYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKNILDRQEGYISEALKSIERL"
     gene            complement(2023..3120)
                     /locus_tag="PC592_000877"
     CDS             complement(2023..3120)
                     /locus_tag="PC592_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF4054885.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKVAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKMKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEVNMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKSTERFNKYGLRTAVFVTSQNESTFGPWPITDGLPTIEIHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DNLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(3353..4699)
                     /locus_tag="PC592_000878"
     CDS             complement(3353..4699)
                     /locus_tag="PC592_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4054886.1"
                     /translation="MLDKFTEFLDIKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYIKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKVVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEVY"
     gene            complement(4789..5097)
                     /locus_tag="PC592_000879"
     CDS             complement(4789..5097)
                     /locus_tag="PC592_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054887.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGTKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKGFADEVGVPCALIKAQAYSPLGGPKLLKQVQELLSE
                     "
     gene            complement(5363..5752)
                     /locus_tag="PC592_000880"
     CDS             complement(5363..5752)
                     /locus_tag="PC592_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054888.1"
                     /translation="MSNNKKKKNNNYKNAKITKSNKNTKREMEKNQKTDYNIPTISFK
                     SGLILIVSSLVSTVIFPVLLSIFGIDNRLGVIIGNSLITSFAVAYTRYFIETKRGFSL
                     GFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(5754..6914)
                     /locus_tag="PC592_000881"
     CDS             complement(5754..6914)
                     /locus_tag="PC592_000881"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDF4054889.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGSGRNTKIKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCYKANFNIENLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAHETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNVALQNIGGIGNITIIPKSCNIEDVFAFDTGPGNMIIDGVCQKLFNKRYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQSPPKSTGREIFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIRYIKELLLGVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKSKVILGNITPKPFGGK"
     gene            complement(7334..8353)
                     /locus_tag="PC592_000882"
     CDS             complement(7334..8353)
                     /locus_tag="PC592_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4054890.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNRYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYINLYNCIEDSGEIDSYLVDGQSFEENLIKDIIENLK
                     MKNNSDIESYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSNIEDSLDIKNQIAKI
                     NFLVNSILYSSRSNTMFEDLFVNKFNLDKMVRMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYILEQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGLYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LNLDS"
     gene            complement(8347..9027)
                     /locus_tag="PC592_000883"
     CDS             complement(8347..9027)
                     /locus_tag="PC592_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4054891.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEIVLDEFVDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIDILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(9179..11086)
                     /locus_tag="PC592_000884"
     CDS             complement(9179..11086)
                     /locus_tag="PC592_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF4054892.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPIIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMNRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSKVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMVSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(11087..11839)
                     /locus_tag="PC592_000885"
     CDS             complement(11087..11839)
                     /locus_tag="PC592_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054893.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPAVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(12157..13311)
                     /locus_tag="PC592_000886"
     CDS             complement(12157..13311)
                     /locus_tag="PC592_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4054894.1"
                     /translation="MINKAIKFRFIIFYFLSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDKINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTSKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYNSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSVNIGYNYTLMVLSLFGCLAYGLIVLLNYLKE"
     gene            complement(13314..13781)
                     /locus_tag="PC592_000887"
     CDS             complement(13314..13781)
                     /locus_tag="PC592_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4054895.1"
                     /translation="MFFKRKKEVITINSYIDGRIINLEEIPDKVFSTKVMGDGFAMIA
                     KDNALKSPAKGVISFIAQTNHAIGIKLQNNVQILIHIGLDSATTKKENFKLKVKQGQE
                     VNMGENLVEIDNKLLENTLYIPLVIIENPNTVKYHLSNLHQEGNSGIKVINFD"
     gene            complement(13795..14283)
                     /locus_tag="PC592_000888"
     CDS             complement(13795..14283)
                     /locus_tag="PC592_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054896.1"
                     /translation="MITNKIKNVTAVLKDENIFLSVIMGCFLILPVLYIVYLELTSLF
                     TNISFSELLNNDVNASLNLVSNFSAVYSAYVIYNLKKNKDIKENMIAFYLVLLGQIFQ
                     IYTLTIVIMFTYVYKFVGIKQIISSIKELQWGKSYKALFSSVAVCLISLFIMIIRIKL
                     IM"
     gene            complement(14297..15628)
                     /locus_tag="PC592_000889"
     CDS             complement(14297..15628)
                     /locus_tag="PC592_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF4054897.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVDKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGVAYGLRTIGPVIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(15642..17207)
                     /locus_tag="PC592_000890"
     CDS             complement(15642..17207)
                     /locus_tag="PC592_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF4054898.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYVHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHVQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFAAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFIAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYIIQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDTEETKLYTKNEYLEAKDEKGNKLSKASQQAAE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(17376..18161)
                     /locus_tag="PC592_000891"
     CDS             complement(17376..18161)
                     /locus_tag="PC592_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF4054899.1"
                     /translation="MRLEEMIFLNYNKLNETDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(18326..19525)
                     /locus_tag="PC592_000892"
     CDS             complement(18326..19525)
                     /locus_tag="PC592_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HDF4054900.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLENKDEYIKRIRSTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKEVVDRYDSMNPKIKMPDDIFVKKELILKDVIKG
                     KIGYMYLPSMSSKNGSINNDLKIIGDYISTLKKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTTARNIKLNPVESLPASVKENAPKEIIKDFNGFE
                     DTSYTIKSTDDLKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKSGVCDEEFKTTPEFKVKDCKRTADFKEDNCIRKAL
                     EFENINY"
     gene            complement(20047..21384)
                     /gene="xylA"
                     /locus_tag="PC592_000893"
     CDS             complement(20047..21384)
                     /gene="xylA"
                     /locus_tag="PC592_000893"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDF4054901.1"
                     /translation="MNEIFKGIGQIKFEGVKSNNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKANMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKVNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(21488..23035)
                     /gene="xylB"
                     /locus_tag="PC592_000894"
     CDS             complement(21488..23035)
                     /gene="xylB"
                     /locus_tag="PC592_000894"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDF4054902.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDSEGKTLRKSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEVTG
                     YVTKDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLDEDVYDIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDTIIKTSTKLEPISENVDIYKTYHRLYKKIYKSLKDDFRLLDE
                     AVNCKNK"
     gene            23243..24403
                     /locus_tag="PC592_000895"
     CDS             23243..24403
                     /locus_tag="PC592_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF4054903.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSMSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHDSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKKLYYEDNQNTKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(24559..24963)
                     /locus_tag="PC592_000896"
     CDS             complement(24559..24963)
                     /locus_tag="PC592_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4054904.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTNELVVKLEKIGKDNISMVEQNTSLLSDDE"
     gene            complement(24984..25466)
                     /locus_tag="PC592_000897"
     CDS             complement(24984..25466)
                     /locus_tag="PC592_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054905.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKM
                     HNINVGNMSSRKDTTVLKPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(25486..26295)
                     /locus_tag="PC592_000898"
     CDS             complement(25486..26295)
                     /locus_tag="PC592_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF4054906.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIIVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(26288..27067)
                     /locus_tag="PC592_000899"
     CDS             complement(26288..27067)
                     /locus_tag="PC592_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4054907.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQAQQYTVVGGMDEDE"
     gene            complement(27067..29145)
                     /locus_tag="PC592_000900"
     CDS             complement(27067..29145)
                     /locus_tag="PC592_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HDF4054908.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     KFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEIECPLEEIPIFLKQDSSYNFKE
                     LKNILSEVKS"
     gene            complement(29753..29920)
                     /locus_tag="PC592_000901"
     CDS             complement(29753..29920)
                     /locus_tag="PC592_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054909.1"
                     /translation="MTGYVANISQTSQALCGIRSINGIIPIVLTVAMLVQMYSLAERK
                     CREVINELRSK"
     gene            complement(30091..30612)
                     /locus_tag="PC592_000902"
     CDS             complement(30091..30612)
                     /locus_tag="PC592_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF4054910.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPYVRQFGEYLKNNYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCSELMDKINDIQMVEGKGIFIEELEKLLKEYNLE
                     IPIVGFDEIREGK"
     gene            30778..31344
                     /locus_tag="PC592_000903"
     CDS             30778..31344
                     /locus_tag="PC592_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF4054911.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISNKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTYSHS"
     gene            complement(31615..31788)
                     /locus_tag="PC592_000904"
     CDS             complement(31615..31788)
                     /locus_tag="PC592_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HDF4054912.1"
                     /translation="MSNEKYIIKNILLKTLRKLRNNNSYGYDISEFKDMYELFIENED
                     VFVSIRKLAKYDF"
     gene            complement(31865..32734)
                     /locus_tag="PC592_000905"
     CDS             complement(31865..32734)
                     /locus_tag="PC592_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF4054913.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRAGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDELDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIETVKC"
     gene            complement(32754..34670)
                     /locus_tag="PC592_000906"
     CDS             complement(32754..34670)
                     /locus_tag="PC592_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDF4054914.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKADELIQRCIDG
                     KVAIRKGNSSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDERKNKSAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMVGVLDKSGVLLDKNKFKEEILKREEISSTGFGMGIAIPHAKTDAVKIPRVAVGV
                     SKEGFDFESEDGSLVHIIFMIAATDNGDNLHLKTLSQLSAKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(34673..35593)
                     /locus_tag="PC592_000907"
     CDS             complement(34673..35593)
                     /locus_tag="PC592_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDF4054915.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFNVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLEKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGESIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(35695..36447)
                     /locus_tag="PC592_000908"
     CDS             complement(35695..36447)
                     /locus_tag="PC592_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF4054916.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINQSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(36839..37114)
                     /locus_tag="PC592_000909"
                     /pseudo
     CDS             complement(36839..37114)
                     /locus_tag="PC592_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898145.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(37501..38280)
                     /locus_tag="PC592_000910"
     CDS             complement(37501..38280)
                     /locus_tag="PC592_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HDF4054917.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDLCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLMGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEEVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LVQERVYEHAMLCDKEVKMWLRRNNIELVDFKDIFKANNYI"
     gene            complement(38273..39700)
                     /locus_tag="PC592_000911"
     CDS             complement(38273..39700)
                     /locus_tag="PC592_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF4054918.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNIST
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLAPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTPTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKRKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPIGIIFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEIQLDELRKQADA"
     gene            40091..40813
                     /locus_tag="PC592_000912"
     CDS             40091..40813
                     /locus_tag="PC592_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4054919.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNAEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKIGSEVYYLHRLRYIDNVPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            41010..42677
                     /locus_tag="PC592_000913"
     CDS             41010..42677
                     /locus_tag="PC592_000913"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF4054920.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLSSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEELLKEAHKRDLKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDKTTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGVKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALIILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSHSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNILVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDTIENEMEIKPYESIMIYCK"
     gene            complement(42772..44091)
                     /locus_tag="PC592_000914"
     CDS             complement(42772..44091)
                     /locus_tag="PC592_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF4054921.1"
                     /translation="MEKGIKLGFWSIVLLGINAIVGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGNFIGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKQLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSSSSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLVGSTTPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYPKKYNNVEVK"
     gene            complement(44129..44881)
                     /locus_tag="PC592_000915"
     CDS             complement(44129..44881)
                     /locus_tag="PC592_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF4054922.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CEAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDINPLIWKEEPHNKLGAISPKRDVF
                     DMKLLKYALDMKKPVLGICRGEQIINVAEGGSLYQDLSLIEGAYIKHNQQHLSNIPTH
                     TALIKEDTKLYEILGEKEILVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTKDYDNMKKIFMAIVKEASKEK"
     gene            complement(45125..47134)
                     /locus_tag="PC592_000916"
     CDS             complement(45125..47134)
                     /locus_tag="PC592_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4054923.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGIAMISDKGNVIICNNSLSNILDIQGNIIGKNIDELENENIKKIFRLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSLKMERTKELGMKIAKSDYTVLITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKEDRFRADLYYRINVLPVNIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     SDLPHNLLNITEDFSKEISILKDRTSLEKVKLVMGCLKNANNLNKNIGRNGIVNSINE
                     LGYSITEGEVRGILNILKELDLIICESGRRGSELNRRGKNILNSM"
     gene            complement(47570..49003)
                     /locus_tag="PC592_000917"
     CDS             complement(47570..49003)
                     /locus_tag="PC592_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF4054924.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGTSCSDMCTGGSQTVSK
                     RITRTIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEVPFAITEKYNGWASREVIDLYMNYCEAIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFISQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPNDVVKTQEDNRVMNYFCGDVQVRG
                     EYPTYMNRYFRENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSESKESNTSGNI
                     LGGVKNPYLESSEWGWQIDPKGLRYALNEIYDRYRIPMMVVENGLGAYDKKEPDGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFNWYKQVIESNGERL"
     gene            complement(49019..50443)
                     /gene="ascB"
                     /locus_tag="PC592_000918"
     CDS             complement(49019..50443)
                     /gene="ascB"
                     /locus_tag="PC592_000918"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF4054925.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEGGRGLANVDVIPQGKDRFPV
                     LTGKMKMFECDEEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGIE
                     EVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKDKIKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMIAAGNTYANTCNPLDVWKSIEKDRENYFFIDVQSRGEYPAY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPEVNILTEGNVFESL
                     KNPYLDASEWGWQIDPLGLRITINSLYDRYQKPLFIVENGLGAVDNPDETGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFDWYKKVIESNGKEL"
     gene            complement(50530..52446)
                     /locus_tag="PC592_000919"
     CDS             complement(50530..52446)
                     /locus_tag="PC592_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4054926.1"
                     /translation="MRKYEQLSKEIIENVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSTGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSGSDSPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVFLASKLEKMFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKMKELCIPAIISGICGVTEPAIYGITL
                     PRKKPFIYSCVGGAVAGAVMGVMNVKSYVMGGLGIFGIPNYINPTTGDMTGVYATTIS
                     IIVAIVVGFVLTFFLWKDDTIVEISKDNNSKGAVEKNKREVIYSPIKGEVKALEHMQD
                     AAFSTGVLGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLLTFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHISNSQELITVLA"
     gene            complement(52520..53380)
                     /locus_tag="PC592_000920"
     CDS             complement(52520..53380)
                     /locus_tag="PC592_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4054927.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGDHISKDKI
                     DKIFKLSDPNICDKFKELIADIPMKYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVNVKNVLLWDIKRFYKNEFNIGLKALDYIEKKFEIRLPEDEAGFIALHI
                     VNAQMDQSIKIIYDITQIIQEIANVVKYHYRIVFDEDSVYYHRFITHLKYFAERVVSN
                     NLHENNEDDLLKVIKVKYKNAYKCIEKLDEFIHKKYNYNLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(53733..54920)
                     /locus_tag="PC592_000921"
     CDS             complement(53733..54920)
                     /locus_tag="PC592_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF4054928.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMEEYGFDTIYPYCNMETAFRAELGNNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDINPMVYVHEKEFLSYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(54934..56325)
                     /locus_tag="PC592_000922"
     CDS             complement(54934..56325)
                     /locus_tag="PC592_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF4054929.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKRFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQITPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDSNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFIIPLMVALTVL
                     VMVFLTIGLYLGF"
     gene            complement(56921..58621)
                     /locus_tag="PC592_000923"
     CDS             complement(56921..58621)
                     /locus_tag="PC592_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF4054930.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVYALGLSGIIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NVNKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFLAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYREKQSVDAGKTVYNNAVGDEVDDKDTELVHSIIEGLGGSSNIKNVTNC
                     ATRLRVELNSIDGFYDDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(58593..59996)
                     /locus_tag="PC592_000924"
     CDS             complement(58593..59996)
                     /locus_tag="PC592_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF4054931.1"
                     /translation="MIVNKELIIDYLKSNQENIIKDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIKIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNNKKDLVESLAYYTEIEEVEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLERIKGLNDKGVIIKDILNSYFTDDNHGKKIGIYKEDVDMGVSTICIMS
                     IFLDKNELNMKIDFRYPKGISLEFITNRINEIGKKENLIIDIYKNLKLLYVEPDSELI
                     NKLSSAYKQGFEKEAELFTKGAASYARVLENGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
BASE COUNT        19765 a        10920 c         6489 g        23418 t
ORIGIN      
        1 tttagctact aactcatgac taaagtcaca agtatgcgta gctatttttt aatcaaatct
       61 cgctttattc aaatattttt taagtgattc taatatcaaa tctcctgact taaacactcc
      121 acctgaataa gataccttta tctttgtacc ttgttcaaaa taatgctcta atcctattat
      181 aagcctactt aattcataag ctgcatcatc aaatatttta ctagcagtat tatcaccttc
      241 aataactgct tttaaacata tcgtagcaaa ctttgctatt tctattctat ctccttgtat
      301 ttcatcattt acatatttta ttatgtcata atcattctct atattaagat gtctttttat
      361 taaatcatat aattttgttt ttgaacacct tccatcagac tgcattgtga acatttttag
      421 ggtagccatt cctatataat atgctgaccc ttcatctcct aatacatagc cccatcctcc
      481 acatctgtga agattcccat ctttatctaa agcctgtgct attgaaccag tacctgcaat
      541 tatatttata cctttttccc catttaaaga acctgctaat gctatttcta catcattacc
      601 taaagtataa tttatatggc tatatgcatt ttttgttgct acttctaatg catacaatac
      661 ttcttttatt tttccatatc cagcaagtcc aacaaatgca tacgttattt cttctacatt
      721 tatcttagca tctttacaaa cttcttccaa cccagttatt aataatttcg ttagattatc
      781 aaatcctatt tgattataat gacaagttcc tttggttatg gttcctacta tatttaattc
      841 ttcatctact aatgtaaatg ttgttttcgt tcctccacca tctaccccta aaaaatacat
      901 actatcctcc tacaatattt ttaataattc tttcaatact taatatctaa aaataacctt
      961 ccaatgcagt tcttttaata ttgaaaggtt atcagtatta ttatttattt tacaatcttt
     1021 ctattgattt taaagcttca cttatataac cttcttgtct atctaggata ttctttgcac
     1081 tatccttatc taaaccactt tttatcataa atatagccaa tttaacgcta ttatctgctt
     1141 cttctaagaa tttttctgca acgtcatatt ctacatttgt agctatcatt attattcttt
     1201 ttgctctttc aaccaacttt tcatttgatg tcttaacatc taccatcaag tttgagtata
     1261 cttttcccat cttaaccata gaagctgttg tcaacatatt acataccatt ttttgagctg
     1321 taccactttt cattctagtt gaacccatta ttacttctgc ccctactata atgtttattg
     1381 gtaaatccgc ttttttactc atttcactat tcggattcat agttattgat agtactgcac
     1441 accctaattc cttagcatac tccattgcac ctatcacata aggagtcctt cctgatgcag
     1501 ctataccaca tataacatcc ttagatgtaa ctcctctatc tattatatct tgttttccaa
     1561 gttctttatc atcttcagca ccttctactg ctttaaatat tgcttgattt ccaccagcta
     1621 ttatagcttg aacaagctca aaatccactc cgtaagttgg aggacattct gtggcatcta
     1681 gtatccctat tctcccactg gtacctgctc ctatatagaa taatctacct ccctgcttca
     1741 ttctatctac tattatatta acagcttttg ctatactctc cttttgttct tcaacagcat
     1801 aggctacagt tttatcttcg ttatttatta attctattat gcctaatgta tcttctttat
     1861 ctatttgcaa tgtattctta tttctacctt ctgtaactaa gttttctaaa gtttttatta
     1921 acatatcatt tcctcatttt cttaatatta aatttttaaa cacattttaa ttccaacctt
     1981 catgattata tctacataat aaattaatat tttcataata aattattttg ttgaaggctt
     2041 aaaattaaac ttttgccatg gtttaatgta atctaatata aataattctt cttttcttat
     2101 atatcctact acattcgatt taccactgtt tttcatatca gtcaaagcta tttgtaactc
     2161 ccccgcataa tgaccatatt cactactttc aattactata tctcctcttt ttattatttt
     2221 aggagtatta aatagttcga atttgtatcc tttatattta acacgagatt gagtagacct
     2281 tatcagatta tcagatatat cccctctatt aaaatgtatt tcttcaaaga gtatcttctt
     2341 ctcaacttct cgtatatttt cctctattgc tacatcaaat gtaaccatat cttttctcat
     2401 agaacctaat accttaagct cctcatatgt tggataacaa tttgatatta ttatatcatt
     2461 tatattattc atagctatta tatgctttac ttgaatatct ataggtagat ttctgtgaat
     2521 ctcaattgtt ggaagtccat cagttatagg ccatggtcca aatgtacttt cattttgact
     2581 tgttacaaaa actgctgttc ttaatccata cttattaaat ctttctgtag attttataaa
     2641 gtgttctaaa tttaatccac tatatctgtg tggataaaag ttatgacatc ctatcaaatt
     2701 ctctttgttt ggttggtagt ccattattgt atctatataa ttagtattgt tactcatatt
     2761 gacttctatt ttaaggttct gaggattaaa agtcattaat gcctcttcag accctgtaaa
     2821 tcccatatca agccttattc catctgcctt catcttttta aaaaaagtca aatctttgta
     2881 gcttatttct aattcaccaa atactctggg atttacatca agtattacct caaaaccttt
     2941 aaacttagcg tattcgttta tacttttaaa ttttttaatt atattttctt tagtatcttt
     3001 aactgataat aaacatgaaa atatacgtgt aaatccattt tcagcaacct tatctatata
     3061 atcatatatt tccttagatg ttgttttttc tggataaatt gatattccta atcttcccat
     3121 ctgtgtcatc tccttatatc ctatatgtgt ttaaatttat ttagaattac acgaaacttt
     3181 tttaaaaatt tggtgaaaaa aagtttcata tatatttata aaaaaagaaa agtttacctt
     3241 ttcttttttt ataaacaatc aacaaaatat ctttgttact tatttcataa ctgttatact
     3301 ttgaaattta tactaatcta atatagtttt taattttcaa tatagtttct aattaataaa
     3361 cttcttgctc ttcaactttt tcttcatgaa gcaacctctt atcgtacatc ttgacaaatg
     3421 gatagtaaat tattattgat atagctatac ataataagtt gagaactgaa gctctccaat
     3481 ctccaccagt ggctaaatat gcccctactg gtcctggtaa tgtccaagga gcagtaacta
     3541 ctactctaga tactaaatta gcactcatag caaaccacga aactgttgcc attactattg
     3601 gtgctacaac aaatggtatt attaatattg ggtttaatac tattggtgct ccaaatatta
     3661 ttggttcatt tatattgaat attgctggta ttacagttgc ttttcctaaa gactttccat
     3721 aagctgattt tgctctaaat gcaagaagta aagctaagcc tattgtagct ccagaacctc
     3781 caatccatat aaaccattga aaaaatggtt cagcagcaat acctggaact gcttgacctg
     3841 cagcatatga agctgtatta gcatctaata attgtatcca taaaggtctt gccaatgaac
     3901 ctattattga tacaccatgt attccaaatg accaaaaaaa cgttattaaa aatattagta
     3961 taattactga tggtaatgtg tcagtggctg aaactaatgg agttactagt ttagctatga
     4021 aaccatgcca atcaaatcct aggaaataag taacaatagc cattaaaatt attattaatg
     4081 cagctggtgt cagagcttca aaagaccttg tgactgatgc tggtactgct tctggcatgg
     4141 ttatcttgaa cttagatttg tcagtaaatc tataaatctc aacacctatt atagacgtta
     4201 caatagcaac aaacattgaa cctccaccaa gattagccat tggcatttgc catccttgag
     4261 gaattgaatt ataccaagct aaaagttctg gactcttttc aactaccttt aataaatcag
     4321 gggtaagacc ctctattgca gtaggaacta ttgtcaaaag gaatgtagct gtagctaata
     4381 aacctcctgt caatccatct aacttatatg actttgccaa actataacct atgccaaatg
     4441 tagaatatac tgatataata aaaaatgtca tcctatatgg tagtaatatt gtaactgcat
     4501 tttcctttat atactgagtt accccccatg aatctggtaa tggaggaaat gctaatatca
     4561 agaaaaatga accaactatt ataagtggta gtgaagctac gattccatct cttacagctc
     4621 ttaagtgacg ttgttctgcc aatctagcca tagatgttga taatttaatg tctaaaaatt
     4681 ctgtaaattt atctagcatc ttttctctcc ttaattaata tttattttta ttatcattaa
     4741 aatttttgta aaattaactt tcttctactc tagcaacttc taaaactgct attcactcaa
     4801 cagctcttga acttgtttta ataactttgg ccctcctaat ggactataag cttgtgcttt
     4861 tattaatgca catggtacac caacttcatc agcgaaacct tttaaatagt caaatctatg
     4921 tctgacttgt ggagctacca tagcaatatc ccatccattt ttaacttcat cctcaaactc
     4981 ttgagtgcca acagctaaaa catctatatc tattccattt tttgttcctt ctttttgtaa
     5041 tgcattaact gctatagcac ttgacatacc tgatgaacaa acaaataaca ctctcatatt
     5101 tattccccct tattttttta tttcttttca atcattatag catgtatttt taattacagg
     5161 aatacatttt cacgcttttt tcattattta caaaattact tgtaatttta tttcaaatat
     5221 ttatatctta ttttaatcta tttatatacc taatcattct ttttactaaa attacacaca
     5281 acttcaaata cttatatctt cttttacaaa aaaaagcatg gagactatct cattattacc
     5341 ataaaatagt ctccatactt ttttaaatat gtataccttt atatatccag aagtaaccta
     5401 ttattgcaaa tgacaaagca aataaaatat acagtctaaa aaatcctaaa gaaaaacctc
     5461 tcttagtttc aataaagtac cttgtatatg caactgcaaa agatgtaatt aatgaatttc
     5521 ctataataac tcctaatcta ttatctattc caaatataga taataaaaca ggaaaaatta
     5581 cagtacttac tagagatgac actattagta ttaatccact tttaaaactt atagttggaa
     5641 tattataatc tgttttttga tttttctcca tttctctctt agtattttta ttactttttg
     5701 taatttttgc atttttataa ttattatttt tctttttttt attattagac atgtcattta
     5761 cctccaaaag gtttaggtgt tatattccct aaaataactt tacttttagc ccctgttgca
     5821 gatattacat tagaaaaaga attatttaat gtttcattgc ccaagattac aaatgccaaa
     5881 gcctcctttg catcagaaga atacccatat tcatcctgag ttaatacttc aacccctaat
     5941 aataactctt ttatatatct tattaaagtt agattatgag ctcctccacc tccaattaat
     6001 aaagtatcta cattaacctt tggaagtatg aagtttttat aattataata tatagctttt
     6061 gctgtaaaca tagttactgt tgctatcaaa tcatatttat ctacatgttt atatttgtta
     6121 agcatgttat ctaaatagac ctgtccaaat atctctcttc cagtgctttt tggtggtgat
     6181 tgactaagat atttatgact catcaaatct tttaacattt cttcattaat tttacctttt
     6241 gatgcaaagt atccattttt atcatacctt ttattaaata atttttgaca tactccatct
     6301 attatcatat ttcctggacc tgtatcaaat gcaaagacat cctctatgtt acatgattta
     6361 ggtattatag taatatttcc tattccacca atattttgaa gtgctacatt tttattgtta
     6421 tcactatata ataaaaattc actatatggg actaatggag caccttctcc acctgctgct
     6481 atatccatca ctctaaaatt agatattact tttgtatttg tttcatgtgc tataactgct
     6541 ggttcaccta tttgaagcgt tgaagataca aaattattat aacttcttgg tatatgaaag
     6601 attgtttgac catgagatgc gataaaatcc aaattttcta tattaaagtt tgctttataa
     6661 catactgatt ttacagcttt actaaataaa tatccaagct taaaatttaa gctacaaatt
     6721 aaatcaacac tcgattcctc ttctatacag cactttctta tttcgtcttt tatatcttta
     6781 ggaatttcta gagttataaa ttctatttgc ttaattttgg tatttctacc actcccacta
     6841 atttcagcta gtactgcatc aactccgtct aaggaagttc ctgacattaa acctacacta
     6901 tacatagtta tcatcctttt aagtttatag ttattcctcc ccaatcaaag tattaagttt
     6961 aataatttta gaattaatat tattccatct tgaattatga taatttactc ttacgaaatt
     7021 aattgagtta atcttatata cggtttttac cttagctaaa tcttacctca atttattttc
     7081 agtgtcaatg taatctcatg taattttttt tcacatacaa aacacattct atctccaaaa
     7141 aacatattaa aatagttgct acaaataaaa aacataccag gtatctatct ggtatgtttt
     7201 tcatatataa taattattat tttataagat ggatagagca tcatttaagt cactaattaa
     7261 atcttcacta ttttcaagaa ctaaacttat tcttattctc tatggcgata tattttatag
     7321 cctttataat aacctaacta tctaggttta aataatcaga tatatcataa aaataaatat
     7381 taaaaattgt atatgaacca ttttccgaac atacctcaat ctcatgccct aaactatcta
     7441 tcattttctt tacaaaatac agccccattc cagtagactt atacaattga tttcttccat
     7501 ttttccccgt aaatcccttg tcaaaaactc tagatatatc ttcttcattt atacctatac
     7561 caaaatcttt tatagataat accactccat tttctaattt ttttgaatta aattcaatct
     7621 taccaacttc ctttgaatac tttatagcat tattaataat ttgttctaaa atatatgaca
     7681 tgcatttaga atctgtataa acatcatttt ctaattcatt caaactaact tctacattat
     7741 tttttataag caaaaatgaa ttatttttta tagacattct caccatttta tctaaattaa
     7801 atttatttac aaataaatct tcaaacatag tgttacttct actactatac aagatagagt
     7861 ttactaagaa atttatcttt gcaatctgat tcttaatatc caaactatct tctatgttac
     7921 ttaacctatc tgtaattata cttaaagaag atattggaat ttttatttca tgaacccatt
     7981 tagctatgta ttcatctaat tcttttaaag actgtttata actctctatg tcactattat
     8041 ttttcatttt taaattttct ataatatctt ttattagatt ttcttcaaaa gattgtccat
     8101 caactaaata actgtctatt tcaccactat cttctataca attatataaa tttatataac
     8161 tatttctaaa atttatataa tctataacaa aaaataccat tattataaac agcactaaaa
     8221 aatctaagta tattaactct gaatatctat ttttaaaaat atctatagca aataaataga
     8281 tatttattat actaactaca actaaaggta gagcaatata cttagaccta ccttttaaat
     8341 attttactag cattgtatta tatatcctat tcccttctta gtttttataa aatcatcaaa
     8401 acctaattct ttaactttac ttctcaatct attcatattt acagtaagtg cattgtctgt
     8461 cacaaactca tcattatccc atagagtcat cataagactt tcccttgata caaccctatt
     8521 cttatttttt aataataatg ttaaaatttt tatttcgttt ttagtcaact ctatactttt
     8581 atccttatac ttatgtttta taatcccttt ccccacatca aacatcaaat cttcacaata
     8641 caaaatacta ttagaatcac tataattata gactcttctt attataccat ttattttggt
     8701 aaccaatatg tctatagaaa atggtttggt aatataatca tctgctccat tatttatacc
     8761 cattattaaa tccatatcag aatcccttga tgataaaaat attaatggta catttgaaat
     8821 agctcttatt ttttcgcacc aataaaatcc attatataat ggtaaattta catctaaaag
     8881 tactacatct ggttttttat ccacaaattc atctaatact atctcaaaat catcaattaa
     8941 ttctacttta aatccccatt tctcaagtgc taacgcaatc tcttttgata aatcaatatc
     9001 gtcctctact aataaaattc tatacatttg tatattctcc attatcctaa tatttcacta
     9061 tgccacgaat tattaatatc ataacatatt ttatataaat ttattaccca aatcatttag
     9121 ttaatcaaca aggagactct tattacaaga atctcctttc tctttattaa tatataaact
     9181 aatttttata cactacactc ttaaacttat taacagatac tgctccatat attatgaata
     9241 ttatcaaaca tatcactaaa cttagtatat atataccaaa taagtcggtc atcaataaat
     9301 ctcctgctaa tctcaatgca aaataactag atatagttgc acttaccatt ggcaaagtat
     9361 aaaatatagc tacttcttta agtatagctc tatttatatc tttttctgta gtacctattt
     9421 ttaataaaat cttgtatttt tctttatctt catatgcatc actatatatt ttcatatata
     9481 ttatacttcc agctacaatt gcaaagacta agaataaaaa cacaagcact acatatgcaa
     9541 acttcatcca ttgactctcg ccttgagctt tatatccatt ctgaatatat ccatttttta
     9601 aacttaagtt cttttcaata ttgttgaaca ttactttgct attttcttct tgaaatacct
     9661 ttgcaccata aaaatatact tgttgaccct tatctcttaa tttgaaatat gtatcgtcat
     9721 ttactactat gatactttga ttaagtcctg tccctagtac tggaactttt acttctcccc
     9781 ttgaaatatt atataactga ccatcaagtt ttatcttggc ttcttttgta gctattgatg
     9841 ctatcgtttg agggcttttt aactctatta cattatttcc actaactaat ctttcaccat
     9901 actcttttaa ttctttatca ttgccattca ctttaagagt attacaaaaa tcactatatt
     9961 tcattatagt atctgttgta tcataagctt cttttatatc tgttttcttt aaaattgtta
    10021 gttctgggtt tactgaatac tttatcttat tagtatcttt tattatattc tctatttgtt
    10081 ttttattcac ttcatcttta tccattgaaa ctatgctaat agtgtacaca tttctttgtt
    10141 cttgggcatt cttatgtata cgattcatcg caactgaagc accaagagtt gatattgttg
    10201 tagttataat tatagctatt atagcataag ttttatagtt tttatttaat cggtagttta
    10261 tattgtttat tgcaattata ttatttccat taaataatat ttttttattt ttgattataa
    10321 tatcaaatat aacaggcata actgatttga ataagccata agtacctact attattatac
    10381 ctataatagg tagtacacta gttatatctc cagttcttat attagtagaa agatagtagc
    10441 catatcctat tactataatt gatactatag ctaatatata tatacctatt cctacctttg
    10501 gtattttttc ttgtttttta gatatattga ttagatttat tacactactt ctacatattg
    10561 ttataaaacc ttttacagcc attattataa atatagaaat aaatattaaa gtagcatata
    10621 gtatagcttc tatgctaagt ccattagata cctttatatt aaatccagat aactttatta
    10681 tcactacttg aaaaaatcta gatgttatta tccctataat tattcctgtt atacaagaac
    10741 ttattcctat aagcatattt tctacaaaat atatttttcc tatagtatat aaatctaatc
    10801 ccataaagga caatattcca atttctttag acctattctt aaaaaatata tttgttgcat
    10861 accatataaa gaaaaataaa aatactgata gtatcattat tacagctact aacactgata
    10921 gtgtaaattt tttattttcc tcttgtaaca catttatagc atcaccatat ctcaataatt
    10981 caaaattagt tagcacaact actgaaaaaa ccatagatat aaaaaatgct agataagttc
    11041 ttatgttact cttaaaatta ttataagcaa ttccaagtat actcacttac atctcacctc
    11101 ccatagaggc tagcatatcc ataatctttc cataaaattc ttttctacta tttcctttgt
    11161 ttaatttaca ctttatattt ccatcattta tcatatatac ttcatttgaa tagcttgccg
    11221 ttagagggtc atgtgtaatc attataatag tagcgttgtt ttctctgttt attttttcta
    11281 atgattctaa aagttcatat gctgatttag agtctaaggc acctgttggt tcatcagcaa
    11341 atatgactgc tggatttgta attaatgacc tagctgctgc gcctctttgt ttttgtcctc
    11401 ctgataactg atatggatat ttatctaaat gattttctaa tccaaatttt ttggctatag
    11461 aaaatacctt agcttctatc tccttacttt tcttttttcc taatgctaga ggaagtgcta
    11521 tattgtccat tagtttcata ttgtctaata gattatagtc ttgaaatata aaccctattt
    11581 tttctcttct tagttttgat agttcattat tttttacttt tgatatatta attccatcta
    11641 gtattatttc tcctgaagtt tgtttgtcaa gtgtagacat taaatttagt aatgttgtct
    11701 ttcctgcacc agatggaccc attatcgcta taaaatcacc ttcattgact gtaagagata
    11761 tattttttaa cacatttgtt ttaaatcctt ttattccata atcttttgag atatttttta
    11821 tttttaatat ttctttcata ataatagcct ccagttgcta attttttaat atatctttat
    11881 tttaaaggtt ttatataaat aaatccttaa gtaaatatta cattttaact gttagcatta
    11941 cacttttgta acatatggaa gactattata gttatagtgg aaatatctta aaataaaagc
    12001 atgattcact tttttgtata aacaaagaaa agaagcccct aagaagcctc taatctatac
    12061 aataattctt ctctataaaa aaccaaaaat acaaccttga ttgtggtaaa tacaggtact
    12121 ataaacaatt gatattacca ctatatatta aaacaattat tccttaagat aattcagtaa
    12181 gactatcaag ccataagcta agcatccaaa aagacttaat accattaatg tataattata
    12241 accaatatta acgctcaaaa aaccagcaac agttggaata atcagagatg acccccccat
    12301 aaatatactt aaagctatta attggctact acttctaagt tttttaggag aaacttcaaa
    12361 tattaatctt tttgaagtaa ttaaaattaa aggagtagaa aacacttgaa aaacacacag
    12421 tataataatg atatttgaat catttgttaa agcaaataat agaaactgaa ctgttatcat
    12481 aatagcactt aattttaata agtttaaact gttatatttt tttaataaat aagaaccagc
    12541 taaatatgtt ggtatctcta ataatgactg taaagaccac tttaaagata tttgagaatt
    12601 tgtagcattt aaagctatca ttttatctat tacagtacag ttatttgcta ccaccattga
    12661 atatagtaaa aataaaatac atactagtaa gatatatttt ttatctttta ataattcaat
    12721 aatatcttta ctggttacat ttattttttt gttaatcttt tcaatatcag gtagtaaaag
    12781 tatatttata ataagtaata ctacaattaa accaatagct acagataatc caaaatacga
    12841 gaatctaaga atcaagtaag atgccaccat acttccaata gcccatccaa ttgacccaaa
    12901 agtcttaata aatgacaaat aattattaat tttatctcca caacctatta tccatgtatc
    12961 atataaacta cagcaagtat ttaataatcc tcctgacaaa gcaacaagta ataagtatat
    13021 tataaaagtt gcagattcag tagaaaacat aataactgat gcaattccat atactgatag
    13081 actaattaaa acaatttttt tcattgtttg atacttatca gctaatactc caaataataa
    13141 ttgaaataat atattggtta ttgcatagct tgataatata attcctcttt caaatgctga
    13201 gtaacctaat tttgataaaa aaggtgtgaa ttttgttgat gcaaaggcaa aaataatata
    13261 tgagagaaaa taaaatatga taaatctaaa tttaatcgct ttattaatca taatcaatca
    13321 aaattgataa ctttaatacc actatttcct tcctgatgta agtttgaaag atgatatttt
    13381 accgtattag gattctctat aataactaaa ggaatatata aagtattttc aagtaattta
    13441 ttatcaattt ctactagatt ttcccccata ttaacttctt gaccttgttt aacttttaat
    13501 ttaaagtttt ctttttttgt tgttgcacta tccagtccaa tatgaataag aatttgaaca
    13561 ttattttgta atttgattcc tatagcatgg ttagtttgag caataaaact tattactcct
    13621 ttagcaggtg atttaagagc attgtccttt gctatcatag caaatccatc ccccattacc
    13681 ttagttgaaa atactttatc tggaatttct tcaagattaa ttatccttcc atcaatatag
    13741 gaattaattg taattacttc tttttttctt ttaaagaaca ctataaacac tcctctacat
    13801 aattagcttt attctgatta tcattataaa taacgatatt aagcatactg caactgagga
    13861 aaaaagagcc ttatagctct ttccccattg tagttcttta atactgctta tgatttgttt
    13921 aattccaaca aatttataaa catatgtaaa catgataaca atagttagtg tgtaaatttg
    13981 gaatatctgc cctaataaga ctaaatagaa agcaatcatg ttttctttta tatctttatt
    14041 cttttttaaa ttataaataa catatgcact atatactgca ctaaaattag agactaaatt
    14101 taaacttgca ttaacatcat tatttaaaag ttctgaaaat gaaatatttg taaataatga
    14161 tgtcaattct aaatacacta tatataaaac aggcaatatt agaaaacaac ccattataac
    14221 tgaaagaaat atattttcat cttttaatac tgctgtgaca ttttttattt tatttgttat
    14281 catgttttta ttctccttat ttaaaagttg gccagaaatc cttattagcc acaatcattt
    14341 catctaagat ttcttttgct acttttgcac ttggaacagt tttactcata gtaaacgact
    14401 gccataattt ttgataactt ttttctatcc acgcttctac agctaatttt tcagaagcaa
    14461 cttgttgttc cattagacct ttttggaaag ttggaatttt acctatagac ataggctcaa
    14521 ccatatcttt tccaacaaga caaggaattt caaccattgc atcatctgca aaattttcaa
    14581 tagctccatt attaggaaca atcagtaaaa atctttcctg agtattgaat gctaatgcac
    14641 aagctaattc aacaataaat tgagaatgtt cacttgcatc aaaccatgta tctcttgctg
    14701 taccattttt tataattctt tcacattctt cgaatgtatc cttttctctt ctatccataa
    14761 tttcatttgc tcttgtataa tttggattgg catgttcaac agtttcatca gccattaaat
    14821 aatattttaa ataagtatta ggtaatgtag ttggttctat ttctaacaaa tcctttgccg
    14881 ctctcatagt ttctagccaa ctagattctt tatgttgacc ttgaggtgta aattcctcat
    14941 atcctttttt agcacaatat tcctgtaatt taggcattaa atcatttcct tctttgtcct
    15001 taatacttgt ccaccatcca aaatgattca atccataata tctaacatca aaatctttac
    15061 gagaatttaa acctaaaact ctagcaaata tttcctctag acatactggc atatcacaaa
    15121 tattaataat tcttgaattt ggtcttaata cacgacatgc ttctgcaact atagctgctg
    15181 gatttgagta attaagcatc caagcatttg gagaatattt ttccatatag tcaatcattt
    15241 ctatcactgg acctattgtt cttaatccat aggcaactcc acctgctcca caagtttctt
    15301 gaccaacaac cccatatttt agtggaattt tttcatcttg ttcacgtaaa gcatataaac
    15361 caacacgaat ttgtgccatt acaaaatcaa tatcagtaaa tgcttcttct ggatttgttg
    15421 tataactaaa tttaatttct ggatttttct ctctaacaat tattgcacat gcttcagcaa
    15481 cttttctttg tctctcatca ttattatcat ataatttaat tgattcaata ggaaatttat
    15541 caacactttc aattaacatt gttacaattc cagcagtata agtactacct ccaccagcga
    15601 ttagtatcct ctgtcttttt ctttccatct ttccttctcc tttacaataa attttcaaat
    15661 tcttctctta cacttggtac tgaaagtcca ataataatct gaatagcttt tccattatgc
    15721 actaaaccat gtgcacctac tgccttaaaa tcttcttctt tagaaatgat tgagtcatct
    15781 ttcaaggtta atctcagcct tgtagcacag tttgtaacat ctacaacatt ttctgctcca
    15841 ccaactaatt ttatatattc agctgcttgt tgagatgctt tacttaattt atttcctttt
    15901 tcatctttag cttctaaata ctcatttttg gtatatagtt ttgtttcttc agtatcttcc
    15961 tctctaccag gagttttcat atcaaacttc ttaattaaga aagtaaatac aaagaaccag
    16021 ataaacgaaa agataatccc tacaacaact tgaataatat ataccttcca gtgatacatt
    16081 ccaagaggaa gccaatttaa tacaacccag ttaataattc ctccaccaaa atcaccaaca
    16141 actcctaagg caaacgaaat cgtttgcaag catgcatcta aaaatgcatg tactaggaat
    16201 aaaagtggtg ctataaataa aaatgtaaat tctaacggct cagtaattcc agttaatact
    16261 gcagtaagag tagcaggaat cattaaacct aacactttct tctttttttc tggctttgca
    16321 gttacataga aagcagcaaa tactcctaat gaaccaaaca ccttcgatag cccagataat
    16381 gaaaatccaa ttggatacat ttcctttaga gtcttagctg aagtttgaaa gtcctgaata
    16441 tgagtagccc aatatactga tgtaccacct ggaacaacaa cactatcata acaaattggt
    16501 gcatatacaa aatgatgtaa tccagttggt attaaaatct tttgtaagaa cgcataacac
    16561 caaacgccta tatttccact atttataaaa aacgtttgca aatgtctaat aacattttga
    16621 acatgaggcc aaataaagca agttaataat gcaactggta tcataacaaa gaaacaaatt
    16681 gcaactacaa gtgatgaacc tctaaataat ccaataaaat ctggtagttc tttatcataa
    16741 aatctattat gaacataaat aacaatacct gatattaaca aagcaccaac cataccagta
    16801 tctagtgttt taataccagc aatgcttaca agtccacttc cagcacttat ttcagctgcg
    16861 aaatcaactc caaagctttt tccccaaaaa cttaacatag aacctacaaa ataattaaaa
    16921 gtcaagtatg ttgctaaagc ttccatacaa gctcttgctt gttgcttttt tgcaagtgct
    16981 atgggtaaag aaatagcaaa taataatggt aattgattga ataccatcca agctccacta
    17041 gatataacac cccaaaattg gtaccaaata ttttctggtg tagcaagtga acccataatt
    17101 gactgatttt gaaatacaat tgagaatcca accattatcc cagcaaaagc aaataatagt
    17161 gttggtgtaa acattgcccc tccaaaacgt tgtattttct tcatcatata aagtactccc
    17221 ctcctcatat ttttatttta tctttggcct tagatatcta ttattttaac atgttaataa
    17281 atatatacaa tctttggact acattcggag cttattcaca gtcaaataag tttttgcaca
    17341 tttttatgtt caaattttca aaaaaaaaag aatgactaca atttgcaatc aatcccttct
    17401 gtaatcattc tatgcctttt ataaatacta tatttaataa ataacaactc aatcaatata
    17461 aaatataaca ttgtcaattt ataactaggg tgcatttgta aaaatgagat attagtcgct
    17521 gaaatataaa ttgattcatc acttaaatca gtcaatgtat tatttttaaa ctctgtaatt
    17581 gaaattattt tagttcctat taattttaat cttctagcaa tattaagtgt attctcattc
    17641 tcaccactta gggatataat aatcataaca tcatttttac tgacaatatt gtaaaaagaa
    17701 tcatcaaatg ttcttccctc aaaatcatat attatttctt gacatgataa gaacattctc
    17761 tttatctgtt ttgcaaccac attttgaata tcacctgaac cataagcgta tattgttctt
    17821 gattcataaa gaagtttaca caatgcatca taatctttat ttttttgatc ttcaacatac
    17881 ttaattattg aattgcatgc aatatcaaat gactgatttt ctataacatg aaccttttct
    17941 gattcccagc ttaataatac tttaaattca ctgaaacctt ttaaatctaa ttttttaaca
    18001 aatcttgtaa tagttgcacg agacacatta catttcatag caagttcatt tattgacatc
    18061 ttactacaat gttttttatt tgcagttata tatttccata ttaataaatc tgtctcattc
    18121 agtttattat aatttaaaaa aatcatttct tctaatctca taaactatta tcccctttaa
    18181 ttaaaaattg tcataactat tataccaata ttcaacatta aattacagca tattcttata
    18241 tttactattt agcctataaa attgactata aaaaatacag ctataattga tgttaaaaaa
    18301 agtagtttta attctattct tttatctaat aattaatatt ttcaaattct agtgcttttc
    18361 ttatgcaatt atcctcttta aaatcagcag tccttttaca atcttttact ttaaattctg
    18421 gagtagtttt aaattcctca tcacatactc cactcttatt taaatacata caacttgcca
    18481 ttctaactat tagaccacta ttttttaaat taaacaatac agggtctata caccctccat
    18541 ctccaccagt agtttcacca actaaagttg caaatttagt ttctttacaa aacattgcaa
    18601 atgactctga tgatgaatat atttttctat caacaagtaa gtatatatta cccttaaatt
    18661 ttaaatcatc tgtagatttt atagtatagg aagtatcttc aaaaccatta aaatctttta
    18721 taatttcttt aggtgcattt tcctttacac ttgctggtaa actttctaca ggatttaatt
    18781 ttatatttct tgcagttgta tattttttta ctatttcatt attatttcta taaattctat
    18841 aaccatttat tttgacatca ttttttatga gtttagatac gattccttgc caatacctat
    18901 cacttccacc taaattacct cttatatcaa taattaaagc tttatgtttt tttaaagtgc
    18961 taatataatc tccaattatt tttaaatcat tatttataga cccattcttt gatgacattg
    19021 atggtaagta catatatcca atcttacctt taataacatc ctttaaaatc aattcttttt
    19081 ttacaaaaat atcatctggc atttttattt taggattcat agagtcatat ctatctacaa
    19141 cttctttatc attaagaaaa tcataccaat cattattaga gtatgatttc ttaaaaagtt
    19201 catatctttt cttgttatct attacttctg tgtgcttatt atttaaatca gataatatag
    19261 atgacagttc ttctataaat tcttcgtcat tttcagtact tcttattctt tttatatatt
    19321 catccttatt ttctaaccaa tcaatattat taagcctctt atttacacct agatatggat
    19381 atcctgtttt tacaacatta tacacataat taaagtcatc taccttttct tcttcagaca
    19441 actgattctt ttgagaataa gtagaattac ctaataagat tataaatgct aaaataatta
    19501 ctaaaaataa tactttcttt ttcatgtaat tctcatccac tttcagattt tatattttaa
    19561 tacattgtat cattatttta ttatcaccta aacaactaaa agaaattctt gaagatatat
    19621 tccactatta ttctctttaa aatattttta tttatatttt taaaattatt tcatgaaaat
    19681 tataaaataa caatcatatt caaatatctg ttttacttcc atatcctgaa agtaaattct
    19741 tatcagtgat atactaaaaa agatgtgcta aaaaatttat ccattataag ggcttaaatt
    19801 tagatacttt actgattttt atttattagt tgagaaagat attgataatt aaaaatattg
    19861 ataactatag aaatgattat tttttatata aatttaagga tataaactaa ttatacttaa
    19921 gtctatatcc ttaatttatc atgattacga aaatttttac aaacacttat atttgtctgt
    19981 tttagaataa aaacaaggac atatcctgtt attttattca aacatccaag tttaattact
    20041 acacaattac ttgttagaaa ttgtatctac ttcatatata tatctgttaa gtatagcttc
    20101 tagcatttct tgtcttccag acttattctt tataactggc atttgcagtg cataagattc
    20161 taactcttta aatccaacct taccttctac tatatcttta cctataccct cactaaaact
    20221 tgcatatctt tctttagtaa agttttcaaa tacctcatct tctaataatt tatgagctat
    20281 taacaatccc tttgcaaatg tatccattcc tgcaatataa gctaggaata agtcttctac
    20341 ctcaaaagat gctcttctta ctttagagtc aaaattaaat cctcctggtg ctattccacc
    20401 ttgctttaag acttcataca tagcaagtgt tgcatcatat atatttgttg gaaattggtc
    20461 tgtatcccaa cctaataata ggtctccttg atttgcatct atactaccta aaacattgtt
    20521 tattctcgct atatttaatt catgttggaa agtatgccct gcaagtgttg catgatttgc
    20581 ttctatattc actttgaagt atttatccag attatacttt cttaaaaatc ctaaaacagt
    20641 agcagtatca aaatcatatt gatgtttagt aggctctttt ggcttaggct ctattaagaa
    20701 ttgtccagta aatcctattt ccttagcata atctacagcc atttgtaaga atcttgcaaa
    20761 gttatccatt tcaagttctg tattagtgtt aagtaaagtt tcataacctt ctcttccacc
    20821 ccagaataca aaattttctc ctcctaagta cttagttatt tccatagctt ttttaacctg
    20881 agctgctgca tatgcatata catctgcatt acatgttgta gatgcaccat gaacaaatct
    20941 tggatttcca aacatattgg cagttcccca taataacttt atacctgtct tttccatatt
    21001 agcttttata tactcaacta tttcatctag tatcttattt gtctcttcta aatctcttcc
    21061 ttctggagct atatctctgt catgaaaaca gaaatactca attcccatct tagacataaa
    21121 ttcaaatcct gcatcaactt taatctttgc tatctcaatt gggtctgtta tattattcca
    21181 aggtctctct actgtaccta ctccaaatgg gtcattaccc tctccacata aagtatgcca
    21241 atagctcatt gcaaatctta agtgttcttt catagtctta ttccctacta cttgttcagg
    21301 attgtagtat ctaaatgcta actcattgtt agattttact ccttcaaatt ttatctgtcc
    21361 tattccttta aatatttcat tcatttcatg tcctcctaat attttacaca tataatatat
    21421 gtagtatgtt ttcttaattt aaaactattt tctatcttta ttttcttttt attttaagct
    21481 atcttgtcta tttatttttg caattaactg cttcatctaa caacctaaag tcgtctttca
    21541 aagatttgta tattttttta tacaatctgt gatatgtctt gtatatatct acattttcac
    21601 ttattggttc taatttagtt gaagttttta ttatagtatc acaagctttt tgtatatttt
    21661 catatattcc agctcctact aatgcaagaa ttgcaactcc aagtgctggt ccttcacttg
    21721 aatttatagt atatacatct tgattaaaca tatctgcttg catctgtctc catactttac
    21781 tttttccacc tccacctgag gctcttactt cattaacgtc tatattaaga ttttctatta
    21841 tatccataca gtctttaaga ctatacgaaa caccttccat tattgacctt gcgatttctt
    21901 ttttagaatg gattggagac aatccaaaga acacgcctct tgcataaggg tcaagatgag
    21961 gagttctttc tcccatcata tatggtaagt aaagcaatcc attacatcct gttggtactt
    22021 gacttacttg attatttata atatcataca catcttcgtc taaagaattt gaaacttcca
    22081 cttcactttg acagaaatta tctttaaacc attttaatga caatccagct ccttgagtaa
    22141 ctcccataac atgccatgta tttggtattg catgacagaa agtatgaact ctaccttctt
    22201 tatcaatttt tggctctttt gtataagcaa atactacacc tgatgtacct atagtggacg
    22261 aaactactcc atctttaact attccatttc ctatagctcc tgctgcttgg tctccagctc
    22321 ctcctaccac tattgttcct tctttaagcc ctgtcaaact tgctacatct ttagtcacat
    22381 aacctgtaac ctcttgtgat tcataaactt tacctaaaag atttttatct atatttaact
    22441 tttctagtac ttcatcgctc caatctcttt ttcttatatc gagcaactgc ataccacttg
    22501 catctgatac ttctgtagca tattcacctg tcaatttgta tcttatataa tcttttggaa
    22561 gaagtatttt attagtattt ttatatatat ctggttcatt gtttctaacc cataatatct
    22621 ttgatgctgt aaatcctgta agtgctggat tagcagttat ttcaatcagt ctttcttcac
    22681 ctactaaatc agttatctcc tcacactctt ttactgttcg ttggtcacac catattatag
    22741 attttctcaa tgttttgcct tcactgtcca gcataactag accatgcatc tgtcctgata
    22801 atccaattcc ttttatacat tcactactta tatttgaact ttgaactact tctcttatag
    22861 attcgactac agctttccac caatcatttg catcctgttc cgcccaacct gatttttctt
    22921 gtataagagg atattcatac gtacaacttt ttatagtatt tcctagttta tcaaataaaa
    22981 ctgttttagt acctgatgta ccaatatcca cacctaatac atactccaac ttcatccctc
    23041 cttgaatgcc acttcataat tatcgttttc ctatcctaat ttttttatat tttaggtata
    23101 ttttacttgc tttatttttg ttagtatatt aaactaactt atgaactaat aataaaatat
    23161 ttaattatct ttgtcaatgc aaaataacct tttatttttg tgtaaaaagt attacaatat
    23221 tattttaagg aggaatatca aattggttac tgataaatac actattcgag aaatgaacga
    23281 aagattagta cttgaacaaa ttataaaaaa tggtcctatt tctagggcaa gtatagcttc
    23341 tactatagga ttgaataaag caactatatc tgctattacc aaaaaactta ttgatgaatc
    23401 tctagttcat gaaataggaa ttggaaatag tactcatagt ggcggaagaa aacccatatt
    23461 attagtattt aataaatgtg cagggatttc tttaagtatg gatattggat acgactatat
    23521 attttcttct atgtcttact tagatggaac tattataaat tctaagaaat taacagatat
    23581 acaagtaagt aaagacaatg ttatacaatt gatagatgaa attataaata gttataacat
    23641 atccaaaata gacactcctt ataaggtaat cggtctcact ttggctatac atgggattac
    23701 ttgtgaaaat aaagtattat ttactccata ttacaatctt aatgagattg acttatatag
    23761 catccttagc aaaaaatatg actttcctat tcatatagaa aatgaagcaa acttaacagc
    23821 tttagccgag aatacttttt caactgtaca tgactcacta ctcagtctca gtattcacag
    23881 tggatttggt tcaggaatta taataaataa taaattatat agtggcagaa atggtatgag
    23941 tggagaaatt ggtcatacta tcatcatgcc taatggtaaa ctatgtcctt gtggaaaccg
    24001 tggctgttta gaacagtatt gttcagaaaa aaaggtattt gaacagcttt cttctttaga
    24061 aaatattcct aagatagatt ctgatatagt aaagaaacta tattatgagg ataaccagaa
    24121 taccaaaaaa gttatccatg aattttgtag ctacttaaca atagctataa ataatgctat
    24181 tacaacctat gctcctgaga taatatattt aaatagccaa ataattagtg atatccctga
    24241 gatattacag attacaaaag atatgttagt tagctctttt aacaaaggaa taaatataga
    24301 aatttcatca ttagggtctg aggcatctct atatggtggc tctgctgtaa atatcaagag
    24361 ctttttgaat atacaaaatt taactttaat taatgaaata taagggttat gactatatac
    24421 agccataacc ctttaaatta tacattctaa aattaaattt attacataga ttacgcaaga
    24481 ttagctatat cttttaaaaa ttgtatatca attaagcatt aacataagta ttttgtttta
    24541 aatattaata taatcttcct actcatcatc agataataaa cttgtatttt gttcaaccat
    24601 agaaatatta tctttaccta ttttctctaa ttttactacc aattcatttg tatctaaaaa
    24661 agctgattca ataaccatac ctaaatttag ccctgaaata attttaattc gactatcatt
    24721 attggctact aataaagcag cattgcatgg agttccacct agtaaatctg ccattataat
    24781 tatttctgaa ctttccttgt acacttctaa agcttttttt aatttttcta ttgttccttc
    24841 tattccatca tcttgtttca tatttacagt aggataatct atagaatccc ctattatcat
    24901 ttttgcagaa tttaatactt cttcagccat attaccatga ctcatcaaaa taatactatt
    24961 cactttaata cacctcttta aatctataag atgtctacaa gataagtttt cttatcatca
    25021 ggcgtcatta tagttgtaat ctcaattcct tcatctaaaa gtcttttaaa tgcttctttc
    25081 tcttcttcag taacactgat attaggtttt agcactgttg tatcttttct acttgacata
    25141 ttacctacat ttatattatg cattttaaat cctgcctcta caaatggaat aaggtccaca
    25201 ggagacttaa caattagtaa tacattttgc ccttcatact ttcctgcagt aatatttttt
    25261 atagcagtct cttctgtaat tatagatgac gctatacctg caggtgtagc cattcttaaa
    25321 acttgttttt gaacagaatt gttagctact gcatcattta ctaccattaa tcttgtaaca
    25381 cctaatttat tactccacat agttgcaact tgaccatgga ttaaacggtc atctatacga
    25441 atatttttaa tacctttcat ttccatatct aataccatcc tttccttatt ttaaaatacc
    25501 taatgcatat aaaattattg aaacaaccat tactcctaaa attaagtata taggttttat
    25561 attcttttta agagcccaat aaacaatcac aactaaaatt gcaggaacta acccaggcat
    25621 aatttggtct aatatttctt gacctttcat tgtaaaatca ccttgttgaa agttcaaagc
    25681 aacattagct tttactactg aaggtattaa ggcacctaca accattaatc ctaaaataga
    25741 tgtgctctca gttaaaatct ttaaactttt ttcaattgaa gatattagct tagtacctga
    25801 tgtataacca gcattaaata gcggtatact taataatttc aatgctacac tcactataat
    25861 ccacagtaag attccaaatg gacttccatc tatcgccata ttagctgcta tagctccaaa
    25921 aattgtccac ggaataacaa caaataaact atctcctaaa cctgctactg gtcccatcaa
    25981 gcctgtttta attgaagcaa cagcttcttc agtctcttca cttgataatt cctccattgc
    26041 tacattaata cccaaaatat aaggtgccac ccaaggatta gtattaaaaa actgtaaatg
    26101 atttaataca gcgctttgta atttttctgg attatctttg tatactactt ttaaaaaagg
    26161 tagtactgca taacagtatg ccaaggcctg catcttctca taatttgaag aaacagaact
    26221 agtaaaaaac cagcgccata agacactttt tttcactttt tcatttgatt tatttaatga
    26281 taccttatca ctcatcttcg tccatacctc ctactacagt atattgttgt gcttgatttt
    26341 ccaaattctt tttgtaaatt ataagtgcaa ttgctccacc aattaaagct acacctaata
    26401 atggtacttt catatatact gctaaaacaa aaccaattac taaataacta aaatactcct
    26461 tagcaggaag atatctaagt aataatccta tccctactgc tggaagtagt cctccagcta
    26521 ctgttaaacc acctgttaac cattcaggcg tatattttaa aattgtatta attaaagaag
    26581 gtccaaatat tacagataga gcaactggaa tacctgttgt agctgctgtt aataacactc
    26641 ctaacatctg catatatgtt atatttttat aatttccttt tttagctcca tcttctgctt
    26701 tatgcactaa ccatataccg atagtatttc taagaacatc taattgtacc atcaataaag
    26761 caactggaat acctatagaa attcctacag atgcttcttg cttagttgta atagttataa
    26821 atgtggctac tatactggct gtctgataat caggtattga tgctccacca aaattactaa
    26881 tacctaatga taatagttgt aatgtacctc caatatataa ccctgtattt atatctccta
    26941 agataagacc agtaataaaa cctgctgtta ctggttgata tgttccaaac attgttgaat
    27001 ttttttcata gtttataaaa aatccatata gtacgattaa taataattgc cataattgtg
    27061 gctccattat gatttcacct cactcaaaat attttttaat tctttaaagt tataactaga
    27121 atcttgcttt aagaaaatag gaatctcttc cagtgggcat tcaatttcat aagttttccc
    27181 accttcataa ctaactccac taaatatatt ttcccatgta tgtccttttg gtaaatatac
    27241 ttttctactt ctatctttat aattcattat tggagctacc aaaatttcat ctccaagcat
    27301 atatgtatta tccacctccc aagttttatc atcttcagga aattcataaa atagagttct
    27361 cataactggt gttccatctt catgtgcttc tttcatcagt ttttttaaat aagtttttaa
    27421 actctctcta atttttataa atttcgtaag aattacttca acttcttcac cataagacca
    27481 tatttcatta ggagctccag ttaccattga gcctccacct ttatttgaca atggtttact
    27541 atgaggcaat ctatctccat gcattctcaa aattggtgaa aaagtagcat attggaacca
    27601 tcttaccata agttctctaa actctgggtc tttaggattt cctccatgga aacctccaat
    27661 atcagtagtc caccatggta tacctgccag tcccatattt aaccctgtat ttacttgatt
    27721 attgaaagcc tcaaaactag agtcaatgtc accagaccat actaaagctc catacttttg
    27781 agctcctgcc caagctcctc tcacaagagt tacaacagac tctatgtcat tatgtaagcc
    27841 atcataaatc atttttaaat aatcaatagg ataaatatta ccacaactta aaacattacc
    27901 ttttttatat ctatagttat caaaatcata cacagaatag ccaggttcag ctacatctaa
    27961 ccaataataa tcaattccaa gttgtttata atttttatct attctatccc aaacatattc
    28021 tcttgcattt tcatttgtca tatctacaaa gactgtattt ccttgaattt gcattgtcat
    28081 tctaacacca cgattaacat tgactaaata accattttct aaataatcat tgtagttttc
    28141 tgcatcactt tgaactgtag gccatacaga tactattggc tctactgaat actcttcttt
    28201 caatttttta actaactctt taggattttt ccaataatct aaatcaaatt tatattcacc
    28261 ttgcttaggc caatgaaaat agtcaattgc aattgatgaa agcttaattc ctcttttaga
    28321 atattccttc acaacatcta aaacttcttc tgaagttcta tatcttagtt tactttgcca
    28381 tagtcctaaa aggttttcag gcatcatagg aacagttcct gtaacttgag aatagttttt
    28441 attcaactct tttgggcttt ctccacaagt aatccaataa tctataaatt ttgtagaaaa
    28501 catcttccat tctgtcatat ttttagcaaa agatactttc ccaatacccg gattgttcca
    28561 taaaagtcca taacctagac tagaaatata aaaaggaact gatatttgag aatttctttg
    28621 ggctaactcc aaaacagtat tctttaaatc taaaaattta tgttgatatt gtcccattcc
    28681 aaaaatcttt tcagaaggct cagattcaaa tctagtagtt acttcaaatt ctccactata
    28741 gcttggtcga tattctcttg attttaactt tagagtagag ttaaaatctt tggtaatttc
    28801 aattgtccct acatcttctc caccatcatc atgttttaca gctcttaatc gaatatattc
    28861 tttcaataat atttcatttt tatcattgta aaaagtaatt ctatctctat ggtctaagac
    28921 agcttttatc tttccatttt taatgattgc acttccatct tcatttttat taattgtaat
    28981 atcatcttta tttaacttag gtttttcgtt aagagcatag ttttcatcaa caaagttttg
    29041 gtctacaaac gacctgatac gtaaagagtt ttttccccat gcttctattc gcaatagttc
    29101 attgtcaaat cttttttcaa tatagtcttc agatattttt atcacggcta cctcctaaat
    29161 caatggtata atattctatc tttgtgtagc ttaagttaaa taatgtcatt tagtttcgtt
    29221 atttataaat tagattttat ataattcatt tgtacattaa actaacttac caataatata
    29281 ctttatttga ctttgtttgt caatcgcttt ccggatttta gtaaaatttt ctaatatatt
    29341 gatggaaagt catccttaat attttttatt tatacttttt aatatctgtg atgataccta
    29401 tatacatcta gatttttaaa acacatacag gaataatgtt tacctcttat gtaaacaata
    29461 ctggacttaa aaatatgtat agcgacctta taaatacaga tgataatata ttagatatta
    29521 ttcaaaacaa aggattttat aattataaat aatttatgaa attatttaag aaaatatata
    29581 attgtacacc aagtcaaaaa cggcaataaa taaataaaac taaaaaatac gttgtctcaa
    29641 aatatagata aatttatttt tcatttctga aatgattaaa atatatttga tttaatataa
    29701 aaaagagtgt ctcatgaact aaaaagttca cttttagaca ctcctttata tattatttac
    29761 ttcttaattc atttattacc tctctacatt ttctttcagc tagtgaatac atctgtacta
    29821 acatagctac tgtaagtact attggtataa taccatttat agaacgaata ccacacaaag
    29881 cttgtgaagt ttgagaaata tttgcaacat atcctgtcat agatagtacc aaataccaat
    29941 atgaatatta atgataatat tgattttttt aaatttttct ttaggagtac taattcctcc
    30001 acttaaaaat gcttcatgta ctgtccatca gtcatatttt tctaccaaat atgatgttgt
    30061 ttcataatga gacaataaat atttatacat ttacttacct tctctaatct catcaaatcc
    30121 aactataggt atctctaaat tatactcttt aagtagcttt tctagctctt ctataaaaat
    30181 acctttccct tccaccattt gtatatcatt tattttatcc atcaattcac tacaaccact
    30241 taactcacca aaccaacgtt tagaactaca tgtcttatta tatccacaac ttgggctacc
    30301 atctattgca ataatacttt ttatatcata attatttttt aaatattcac caaattgtct
    30361 tacataaggt attaacattt gcctacattg ttctctaaaa aacaaattgt caaactgttc
    30421 ttttacatgt ccccacctat ttattccata cataatcatt tctggacatg gtagttgaat
    30481 tattccatac cctttattta ttaaatctat tgctatattt tgtgctcctt taaattctga
    30541 caacccctct actttagaat tacaatttaa tatacagtga catactacta caatctctct
    30601 atttctcttc ataataatct ccttagttat tcttaatttt aatgatacta catattttga
    30661 taattatatt atttatttgt tctatatttc caatattcta tatagaaata tacaattagt
    30721 aatcttttat aatctatact atgataaatg tatatatttt tttaggaggt attataattg
    30781 gatactaaaa aagtcacatt ttcttcaatg tgtatagtta ttaatattgt cttaggtatg
    30841 gttatatcta tgataaatat accattatta tttttagata cagttggtac tgtacttggg
    30901 gctgtcgtat taggtccttt ttggggtgct cttattggtg ggtgtacaaa cttagtttta
    30961 ggtgttatat caggacctac aaatatacct tttgctcttg taaatattgt tcttggtctt
    31021 attgttggat atatttctaa taaaaaaggt tttggttata aagaagctat tattacaggc
    31081 gtaattttat ctattgtttg tcctttaatt ggtactccta tttcagtttt attgtttggt
    31141 ggtttaagtg gaagtggtgc tgatttattg gttggttttt tagttcagtc tggtcagaag
    31201 atatttactg ctgcgttctt tccaaggatt cttagtaata tagtggacaa gcctttgtct
    31261 tgtattatgg tggtatattt tataagtaaa atgcctaaag gttttataaa acaatatagt
    31321 aaaaatacgt atagtcattc ttagtaaact gtatatatta tatgatttgc taaaggttat
    31381 aatgagttta tacacattta tttgtataat atattttgca ctttattatt cattaatttt
    31441 agtattggtg atttaattat gtgttatctt tattaattta attaaataca acctcttaat
    31501 ataaatttag gttctaaaac tgtattaaga ggttatattt ttattttata atatatttaa
    31561 agttttatga gaacttatag aatatacatt ttttatttta gttaaaatct ctctctaaaa
    31621 atcatatttt gcaagttttc ttatactaac aaatacatcc tcattttcta taaacaactc
    31681 atacatatct ttaaactctg atatatcata tccataagag ttattatttc ttaattttct
    31741 aagcgttttt aataatatat tctttattat atatttctca tttgacatct taaatataca
    31801 aaataaagta agatatctac tatagatatc ttactttatt ttcatttata attatatttt
    31861 attattaaca ctttactgtc tctattgctt ttcctacaca tccacaaact tccattctac
    31921 tcttaacaaa atctttaact gactctaaac cttttttacc atatttctta gggtcaatta
    31981 cctctgggtc agaattaagc acatccttaa ccccattact ataagcaatc cttaattctg
    32041 ttgcataatt aaccttgcaa atccctcttt ttatagattc cttaataacc tcatctggta
    32101 ttccagaccc accatgtaat actaatggaa ctgatacaac ctctctaatt tcagataatc
    32161 tatctaaatc aagctttggc tctcccttat atagcccatg tgccgtacct attgctactg
    32221 ccaaagatga tacccctgtt ctctctacaa actcttttgc ttctaatggg tctgtatatg
    32281 ctccaccatc accaccatct aattcgtctt ccttacctcc aactttacct aattcagctt
    32341 caacaggtat atctgaaggc atacatgcat ctacaacaga tttagatatt gaaatattat
    32401 cttcgtaact ttcatgagaa ccatcaatca taatagaagt atatccagct ctaagtgcct
    32461 gcatagctag tccaaagctt gaaccatggt ctaagtgcat tgctactgga acacttgcct
    32521 tctctgatgc tacctttaca ttcgctaaat aataatctag tcctgcatac tttattgttg
    32581 aaggtgttgt ttgcaatatt actggtgatt taagctcttc agcagcctct attactgcca
    32641 taaccatctc catattttca acattaaatg cacctactgc ataatgccct tcttgtgcat
    32701 ctaataatat ttgtttagtt gtaactaatg ccataatctc tcctcctata tgtttatact
    32761 gatttgattt cttcgttatt taattttgat actatttccc tacttgtctt gctatttaat
    32821 aactcattta aaaattcttc attcattaat tttgcagata attgagataa tgtttttaag
    32881 tgtaaattat caccattgtc tgtagctgct atcataaata taatatgtac caagcttcca
    32941 tcttctgatt caaagtcaaa cccttctttt gatacaccca ctgctacacg tggtattttt
    33001 actgcatctg tttttgcatg tggtatcgct atccccatac caaaacctgt agatgatatt
    33061 tcttctctct taaggatttc ttctttaaac ttatttttat ctaaaagaac accagattta
    33121 tcaagtactc caaccatttc atcaattaca tctgttttat tttttccctt aacatctaaa
    33181 attactgttt cttcgctata taaagagata ttattagata cgttttccga ttctgcactt
    33241 ttatttttac gttcatcttt agttgcattt gtattttcta tagtattttt ctcatttact
    33301 actttaggtg taaccatcat ataaagtaca gcacctacta atgaacctac aaatatacac
    33361 cctacccata aaagtggctt attgactaat cctagaacca aaaaccctcc atgtggagct
    33421 ggtacttcta ttttcattat ataagttaaa attgatgata ttgatgatgc aatcataagt
    33481 actggcaaca cttttaatgg attttttgct gcaaaaggta ttgccccctc tgttatatga
    33541 gtactaccta gtatataatt gattaatcct gcggctctat cttcttctgt aaatctgttt
    33601 ttaaataaag tggatgctat tgctattacc aatggtggtg ttatacaagc tgcagataca
    33661 cctgccatga ataaataatt tccctgtcct agaagcatag ttccagttac atatgctgct
    33721 ttatttactg gacctcccat atcaaatgct gacatacatc ctattactat tcccaagatt
    33781 atagggcttg aattttgcaa ccctgataga aagttcatca tagcattgtt aagtgctgag
    33841 catggtccac caagtaacaa catggctaca cccacaagac ctacacttac aataggaatt
    33901 ataaaaatag atttaagacc ttctaattgt cttggtaatt ttcttaacaa atgcacaaat
    33961 aatttaacta agtaacctgc taaaaatcct gatatgattc cacctaaaaa acccgaacct
    34021 gtatcgaatg atatcattcc tccaacaagt cctgccaaca taccagctct tcccgatata
    34081 gattgagcta taaatgctgc caacacagga accatcaaat tcatagaata tccaccaaca
    34141 gattttaatg tagctgctat ttgattatat tgttctgaat ttgggtcaaa tgaataaatc
    34201 ccccataaaa atgatatagc cgtcaatact ccacctgcta ctactaaagg taacatgtga
    34261 gatacaccat tcattaagtc tttatataac ttttgaccaa acgataaatt tccttcttct
    34321 gcaattttac tgcttgatga gtttcctttt ctaatagcta cttttccatc aatacacctt
    34381 tgtataagtt catcagcttt atgtatacct tctttgacag gtacttctat tactggcttc
    34441 ccattgaatc tgtccatatc aacattttta tcacaagcaa ctattattgc atctgccatt
    34501 tcgatatctt ttgctgttaa cttattttct acacctatgg ctccattcgt ttcaactttt
    34561 atatcacacc ctaattccct agctgaattt tttaatgctt cttctgccat aaaagtatga
    34621 gctattccag ttggacaacc tgttacccct agaatcattt tctttcccat ttttatacca
    34681 cctttctgac tcttatattt tttatataat cttccacatt ctccaaatta cctataccat
    34741 tactttcagc cacacttgct cctgttgctg ctgacctttt taatgcttct tcaatatgtt
    34801 ctggattttc caaccatata cttaaaaaag cagctaatgc agaatcacca gcacatgcag
    34861 agctgactac ggtaactggt tgggcactag cataataaat tgattctcca ttataaaaat
    34921 aagaaccttt ttctcctaaa gttagtaata tattttgagc gccttttaaa tgcagtaatt
    34981 taagtacatc cttaatatct tcttcatctc ttacaataat tccaaatata tctttgattt
    35041 cttcatcatt tggttttatc aaatatggat tatactgtag taactccttt aattttggtg
    35101 aacttatatc gagtattgtc tttatacttt tatttttaca aatcttaaat atatcctcat
    35161 aataattatc atcaatacca ggaggcagac ttccacttat tgataaataa cttatatctt
    35221 ctaatgactg tatcttctct agcatatcta atttttgttt ttcgtttaca tacgacccag
    35281 agtttacaaa tttaaattca tcacttccat catttaaaaa tatatttata cgagttgtat
    35341 cttctaccca agtaggcaat acattaaatc ctctcttttc actttcttca actatatatt
    35401 ttcctgaaaa acctccaaaa aatcctaata tcttagattc tataccataa tgacctagta
    35461 caaatgttac atttaatccc tttccattag gagaatatac agcatttgat gtacgattta
    35521 ctaattttct ctttatccca ttagtagata tattcatatc tattgcagga ttcgtagtta
    35581 atgtatatat cattgtcttc ccccttgctt gtgctgtgta tgttttcatt ataataaaaa
    35641 agtctatgaa aatcttttca caaatagaaa atcgattttc atagactttt caatttaatt
    35701 ttcagaatta ttatatctga ccatataatc tatgattatc ctagatataa tatacaaggg
    35761 caatctagag gatacttcat attcagaaat tgatatatgt tcatgtttgt atcctacaat
    35821 atataaatct gaatacttta taagttttgc actttcacta caacaacaag ttataacttt
    35881 agctccaact aaattggcat tctgtgctga ttctacaagc tctatggtat ttccattcaa
    35941 tgaaaatata attataagtt cgtctttttt tattgattta gattttattt tcattatgtt
    36001 ggggtcattt ataaaaacaa cattaaaatc aagtaattgc agtttaagac taaactcttt
    36061 tgctacatat tcagtaagcc ctcttgctaa aatatatatc ttactagatt gatttatagt
    36121 ttttattata ttaattagtg tagttaaaga tatttgttct ataactctct gtgcttctat
    36181 aaaggattta tttattatat ctcccatatt ttgtatatca tcattttcat cttttactgt
    36241 taatctatac ctaagttcat tgaatccatt taaaccacat tttctaattg ctcttgaaac
    36301 agttgctgga gatgaatatg tttcatgagc aatctctact atagataatt ctggtaatat
    36361 tgattcattt tcatttataa atttaattat ttcaagttcc gtcttcgtta gattttcaga
    36421 attacttttg tttagctcaa ttatcatatg ttatctcccc ttatataagt tttatttgtc
    36481 taaatttacc gagtaatata atatattacc tcttaactat ttatttttat atacaattaa
    36541 gatttagtca atgtctatat atgtaaattt ataatatcat aattttttac ttaaagttta
    36601 ttatgttatt ttatagcatt ttaagataaa aaagaattgt accgctacta aaatccggct
    36661 gaaatacaat aaatattcct catcctgata tgtttataat taaaggtata aatataaact
    36721 ttgctatgaa tcacataatt aataaatcat tttatttaca attataaccc cccttataaa
    36781 actatattaa taatatatac agtatttata aaggaggtta tttatattta aaaactattt
    36841 acttttctct taattcttct ccattagttc ttattacatt ttgataccaa taaaaactat
    36901 cttttttata acgttctttg tttccatttc cattattatc tatatccaca tatataaatc
    36961 catatctttt ttccatttcc tgagatgaac aacttactat atctattggt gaccacatac
    37021 aataagctaa tatttcagtt ccatcagcta tagcttcacc tatttgctct atatgttttg
    37081 ataaataatc tatcctgtaa ctatcatgaa cttttcagat actcataatc tcggttttga
    37141 taataaagta tacatagtta ttactacttt accaattagt gatagatatc ctataccctt
    37201 tgtttatgta aatccttacc taaacggaaa gaattatgac aatatccaaa ttaaatttct
    37261 tcatattata aggtagaaaa aatatactta ttgtacaaaa ccatttagaa atgtacttta
    37321 gtgaatcttt atttatgaaa aatatctatc tctttttatt atacataaaa aatgtgtact
    37381 tcctatattg atagggatga ttcaaatttt tattttgata catctctatc aatattcttt
    37441 tagaaaatac acattttttt aaatacttat ttttaattaa aactttaagt aatctattct
    37501 ttatatataa ttattagcct taaaaatatc tttaaaatca accaattcaa tattatttct
    37561 tcttaaccac attttaactt ccttatcaca tagcattgca tgttcatata ctctttcttg
    37621 aacaagagaa gatgatttta taagactata atctataaat cctggatgag taaccatcaa
    37681 tgttatatct ttatctaaat ttatatactt ttcttcaaat aatttaacaa aagatttatt
    37741 taacttataa aaatcattct gaggatattt acttggcata ctaatacatg aatctaaata
    37801 atagggacaa cttggtatac catattcttt agcagcatca cacattgctg atattgatac
    37861 ctcttcttct ataccatgta tatcaatata ctcaggcaac ttactcatat acaacttgta
    37921 agtttcaatt tgagcacaaa cttcttcata tacttcttca taattaaaaa cctctttacc
    37981 catcagtaac tgcgttcttc ttattttgct agaaacaaat tttccacctt catctaacaa
    38041 attctttatc ttaatatgtt ctttgcaaca aggttctcct attactaagt taacatgtaa
    38101 accaaaacat aaatcatcat tttttaccat ttctatggct tgtcttgaaa aaggcatatt
    38161 caccatgatt ccggcacttg taacaatacc attcttataa gaagatatta taccgagtgt
    38221 aacaccttct gaatatccta tatcatctgc cctaactact aatttcttca ttttatgcat
    38281 ctgcctgctt tctcaactca tcaagttgta tttccatctc atcctttact ttaacaacat
    38341 ccgttcctat gattatttga actgatgtat tactcaattt aattacccct ttagctcctg
    38401 tttttttaat attatcatca ttcaaaatag tggcatcttt cacttctaaa cgcaaccttg
    38461 tcatacaatt attaagagtc actatatttt cataaccacc acaattttta attatctgct
    38521 tagccatata tgaaaaatta ccatgagaaa gttttaaatt cttttctttt tcactaactt
    38581 tatcacctat ctctatctca acttcacgtc ctggtgtttg tacattatct tttattatta
    38641 tatatttaaa tgttacataa tataatacaa agaatataat tcctataggt ataactaacc
    38701 atgctttatc tccataacta aaacttaaaa cataatcaat tatacttgct ccattaaatg
    38761 aacccaagcg agcacccagt aaatatagta caactccacc tagaccagaa taaaaagaat
    38821 gaattatata taactttgga gatgcaaata aaaacgaaaa ttctataggt tcagttactg
    38881 ttgccataaa agaagtcaat gccccagctg tcattgctcc ttttacttct tgtttccttt
    38941 tatcttgtgc tgttttatat atagcataag aaatagcagg tattgagaac atcataatta
    39001 tgtaaaatcc tgtccagaag aatcctgcat ttgggtctcc tgccataaat ctaggaattt
    39061 ctcctcttat aacttctcct gttggtgttg tatattcacc catttcaaat aatatgtaag
    39121 catttaaaac ttgatgtaac ccagttggta ttagtgcacg gttacagaat aaaaataaga
    39181 atattcctat tgcaccagct cctcccaacc aaaaaccaaa ttgattcatt gcagcttgtg
    39241 gatatatcca taataaacta aatatatatg ataaaattaa agcaactact ggtgctagtg
    39301 taattacaca tttttctcct gcaaagaagc ttaaaaatgc tggaacttta actttatatg
    39361 ttttattgta agtccatgct atacaggctc caacaattat cccaccaaat acacctgcat
    39421 ttaatgtatc attcaataac tctaaatttg acttaaatat catatatgca actactgctg
    39481 caaccattac acttgtctta tctttagact ttgagtaggc actagctgct cctaataaaa
    39541 ataagtagtc cacatttgaa aatactatag tagatatatt agatatagct ggtacattaa
    39601 gcatatttgg tccaaataat aatcctaata tacctgctgc tggcattaca gctattggca
    39661 ctagcatagt ttttcctaaa agtgacagtt gttgcatcat tttgtttaag aatctcttca
    39721 tatccaatcc cctttctatt tcggtttaat tttttgtgaa aacgatttgt ttacatttta
    39781 tattttaaat attatatttg tttaaacaaa ttgtcaatat tttttattta ttttatcttc
    39841 atcatttagt ttcacatcta aactcttttg agtatattgc tatatctagc ctattttttt
    39901 agttcatttt ttttattttt aaaatatgtt taaccattta tttgaagtaa gctacaaaat
    39961 agttcagttt tatctttttt atagcttata taattctatt ttcactatac atgtctaaac
    40021 acatttgata taatttgttc atatcaattc aataatatta ctaaagacct ttaaggaggg
    40081 gtaggggtat atggctaaaa ataaattttc agagatatat gaagtattaa aagaagaaat
    40141 acttgatggt aaatatacaa gtaatatgat gttgcctact gagcttcaac ttattgaaag
    40201 gttttcatgt agcagaaaca ctgtacgtag ggcaatttct caattaaacg cagaaggata
    40261 tgttcaaagt ataaaaggca agggtgttgt agtgttagaa aatagttgtt ctaatgattt
    40321 ttttctaaat atgcataatt tcaaaggtgt agaatcgatt gtagaagata aaaaggttaa
    40381 tactgctact agtgttctcc acttcagcaa aatcttaatt gataataagt tatctaaaaa
    40441 gacaggtttt aagattggta gtgaagtata ttatcttcac agactaagat atattgataa
    40501 tgtacctaaa atactagaca ttaactattt tctatgcagt atagttaaag accttgatgt
    40561 ttctatagca caaggctcta tttataaata tatagaagag tgtctaggta caaaaattgt
    40621 ttcatccaga aagatattta aaattgaaaa agctacagag cttgagttaa aaacgctacc
    40681 tctaaatgat tataattgtg ttggtgttat taaaaatagt gtatatactg atgatggaaa
    40741 gctttttgaa tatactgaat caaagcatac acctgaaaca tttgtattca tggatgttac
    40801 tcaaagatat taaaaaaatt atgtttaatt aaacataatt tttttacgtt tagacacttt
    40861 atactatact aatctcacta ttctataaat aattatatgt ttatacaaat aatcatttat
    40921 tttatatttt acctttagtt tcagttttat tcttgacaat ttgtttaaac atattataat
    40981 taacttataa attacaggag gtatcaagta tgaaaaattg gtggaaaaaa gcaaccgtct
    41041 atcaaatata tccaaaaagt ttcaaagata gcaacaatga tggtataggt gatataaatg
    41101 gtattataga aaaattagat tatctttctt cattaggtgt tgatttatta tggttaactc
    41161 ctatgtacgt ttctcctcaa agagataacg gatatgatat agaagattat tataatatag
    41221 acccaaaata tgggacaatg agtgactttg aagagctctt aaaggaagct cataaaagag
    41281 acttaaaaat aatgatggat atggttctaa accatacatc tactgaacac aaatggttta
    41341 aagaatctaa aaaaagtaaa gacaacccat atcgtgatta ttatttctgg aaggatgcta
    41401 aacctgatgg ttctgtacct aataactgga tatccaggtt tagtggaact gcttggaaat
    41461 atgataaaac tactaaccaa tattatttac atttatttga ggaaactcaa gctgatttaa
    41521 attgggaaaa tgaaaaagtt cgtgaagaat gttacaaaat actagaattt tgggccgata
    41581 aaggtattga tggttttcgt ttggatgtgg tcaacctact atccaaaaca cctggattac
    41641 ctgatgaccc tataacaggg ccaaagggag atggaagaac tcactacgct gatggtcctc
    41701 gtatacacga atatttacat aatatgaatc aaaaagtttt caaacctaaa aatatagtta
    41761 ctgtaggtga aatgtcatcc actacacctg aggaatgtat caactatact agagaaaatc
    41821 gagaagaact atctatggtt tttagctttc atcatatgaa aacagattat aaaggaggcg
    41881 taaaatggac taatgaaatg ttctctttgg ataaattaaa aaaagcacaa tctgactttc
    41941 aatataaaat gtatgaagga aaaggatgga atgctctatt ttactctaat catgaccaac
    42001 ctagagcttt gtctcgattc ggagatgata gattttttcg tcaagaaagt gctaaaatgt
    42061 tagccataac actatttggt ttacaaggta ctacctatat atatcaaggt gaagaaatag
    42121 gtatgacaaa tgcctacttt actaaaatag atgaatatga tgatgccgag agtaaaaatg
    42181 catactatca tatgattaaa tctggcattg atgaaaaaga agcattgatt atacttcaac
    42241 agaaatctag agacaatgct cgtactccta tgcaatggga taataccatt tataagggat
    42301 tttctaatca taaaccgtgg ctaaaagtta ataatgacaa cattagtgta gaaaatgagc
    42361 ttaatgattc tcattcagta ttttatactt atcaaagatt aataaaatat cgtaaacaat
    42421 atgatatttt tacagaaggt acttatagat tgttagatga aaatcataaa aatctatttg
    42481 tttatgaaag agagtataaa aaccaaaata ttcttgttat aagtaacttc actcatgata
    42541 atgtagtgta taaattacct gaaacctatt tgaataaatt aaactacaca atacttgaaa
    42601 ccaattacac tagagataca attgaaaatg aaatggaaat aaaaccttac gaaagtataa
    42661 tgatatattg taaataaagt tatttatgta aaaatcggta taacatcaga gtgttatacc
    42721 gatttactaa attcaaaata atatttatag aatctctata aattacaata attatttgac
    42781 ttctacatta ttatatttct ttggatatac tttagtcata tagaaatata taggaactac
    42841 aattatcatc ccacctaatc cccaaactat cttcataggc tcatctatac ctgcttttat
    42901 cagtaataat atacttataa taactgcaaa tattggtata attgctcctc caggtattct
    42961 aaaatttaca tctttaccag catacttctt tctcaatatt agtacagcta agcaggtagg
    43021 aatatattga ataaatctag atacaacact tatttgagat aatgttgtaa atgagcccga
    43081 ccatgctatt agtagagttc ctatgacaga tactataatt gctatatatg gagctccatt
    43141 tttattagtt tttcttatag acttaggcat taatccttgt tcaaccaaag cagcagcaga
    43201 ccttggtgta aatatggatg atgcaatatt tatacctcca acagatacta tggttcctat
    43261 tgtaattata tacccaccta tagggcctaa catcttaatg gcagcatctg caacaggagt
    43321 agttgaacct actaagccat tacctaatac tcctatactt attcctagta taagcatata
    43381 tattactgat actacaaaca ttaccattac cagtgcttta ggtacatttt tcttagggtt
    43441 ctccatatct tttgctgcaa cagctaaaga ttcaaaccct gtaaaagcat aaaataaagt
    43501 tatagatact gctacaaaag ctgatgatga actttgacct ttttgtatta ttacaaatgg
    43561 tgtaaaatta gaacccttta taaagaataa tcctacagct ataaataaaa ctattggtaa
    43621 taattttcct atagtcatta tattatttaa ttgcttagat tgtttcatcc ccataaagtt
    43681 tataatccca agccctacaa ctaatatacc aattattata tttttagtaa gtggttctgc
    43741 tgcttgtggc catacagatg atagtgttac agcaaagaaa tttgccatag tcgcccaagc
    43801 aatcatacta actatccact tcataaatcc aacttcaaat ccaataaaat ttccaaatgc
    43861 ctcttttgca taaagatatg gacccccatc agtatcaaac caactacctg cttcagcaaa
    43921 acataaagca atagaaacag ctaaaagcat acaaaaaact aatactaata tacttgctgg
    43981 acctatatct gtataagcat caccaggtaa tccaaatata cctgacccta ctattgcatt
    44041 gattcctaat agtacaatac tccaaaaacc taacttaatg cctttttcca ttgttattcc
    44101 ccccaaagcc aacttaatat agttataatt atttttcttt tgatgcttct ttaactattg
    44161 ccataaatat ttttttcata ttatcataat ctttagtcat catttctgga tgccattgta
    44221 ttcctattac aaactcactt ccttcctttt ctatagcttc aattaaaccg tctttagatg
    44281 tagctgaaac aatatatcct ggtgctactt tgtttacaac taaatgatga aaactattaa
    44341 ctaaaatttc tttttctcct aatatttcat ataattttgt atcctctttt atcagcgctg
    44401 tatgtgtagg tatgttagat aaatgttgtt gattgtgttt aatataagcg ccttcaatta
    44461 gagataaatc ttgatacaaa ctacctccct cagctacatt tataatttgt tctcctctac
    44521 atatacctaa aactggtttt ttcatatcta aagcatattt taataatttc atatcaaaaa
    44581 catctctttt tggtgatatt gcacctaact tattatgagg ttcttctttc catatgagtg
    44641 gatttatatc ttgtccccca gatagtataa gcgcatctat attagatact tgttccttta
    44701 taatctcatc atcatataca attggtacaa tatatggtat agcttcgcac ataactactg
    44761 attgtatata gtcattattt acataagctc tttcatagcc aggaaacatt cctccttcat
    44821 caattaataa attacccgat attcctatta ttggatattt ctttttaacc aatttcttca
    44881 ccccttcact tattcgtaaa caataaaaaa tgctacttct cttaaagagc aagtagcata
    44941 ccaatatttt atttatttga atattataat ttattttaga aatacttttt ttaaatacta
    45001 gtaatataaa taactttctt tacttatatt ttattttaat cctgtttagt ttgacttttt
    45061 taaattgttt taagtacaat taataggtaa aataggtatt tatattttcc tttttattaa
    45121 cctattacat gctgtttaat atatttttac cccttctatt taattcactt ccccttctac
    45181 cagattcaca tattatcaag tccagctctt ttagtatatt aagtattcct cttacctcac
    45241 cttctgttat actatagcct aattcattta ttgaattaac aataccattt ctacctatat
    45301 ttttattaag attattggca ttttttagac accccatcac taactttact ttttctaaag
    45361 atgttctatc ctttaatata cttatttctt tactaaaatc ttcagttata tttaataagt
    45421 tatgaggtaa atcacttatt aaaataacat cttcagagct cataatgtta atatacatag
    45481 cagtattttt taattctctt atattacctg gccattcata tgcattaata atgtcttgaa
    45541 catcttgact aattgctctc ttccttttca taaaatgctt caacataact tctatatctt
    45601 cttttcgctc tcttaaaggc ggtatattta caggcaatac atttatccta tagtataaat
    45661 ctgctctaaa tctgtcttct tttatcattt ctaataaatt tttatttgta gctgcaatta
    45721 ctctaacatc tatatctatt acattctctc ctccaactct cattacctga ttctcttgta
    45781 atactctaag taatttgctt tgtaagtata taggcatgtc tcctatttcg tccaaaaata
    45841 tagttccatt gttagcttgt tcaaataatc cttttttacc tccttttaaa gctcctgtaa
    45901 aagcaccttc ttcatatcca aaaagttcgc tttcaagtag attttctggc atagctgcac
    45961 agtttattgc tataaatggt tgactatgtc ttggtgatgc attatgaata gactgagcca
    46021 taagttcttt tcctgttcca ctttctccag ttataagaac cgtataatca gatttagcta
    46081 ttttcatacc taattcctta gttctttcca tctttagcga aactgttttt atatcgtcga
    46141 aagtatatct agcaacttgt cccttttctc taagcttctt tgataggttt tgctccaatt
    46201 ttcttatgta agttatttct tgaatacaaa aataatatcc agtaaccctt ccaaaactct
    46261 ctatattata cttatttacg tttaagtact tattattaaa ttttataact tcatcatgtg
    46321 ccttactcaa cctaaaaatc tttttaatat tctcattctc taattcatct atatttttcc
    46381 ctataatatt accttgaata tctagtatat tacttagact attattacaa ataattacgt
    46441 ttcccttatc tgatatcatt gcaataccta agtttgataa atttattatg gaatttaatt
    46501 catctgcttt tatagtaagt tctttgtatt tagtatttat tcctgagtat aaactaatta
    46561 tttcatctgt atacttaatt agcctctcag taatttcctt atcatccagt ttgagttttg
    46621 ctattatttg aataaatgtt gaactatcaa tatatctatg ccctaaatca ataacttctt
    46681 ctatgtattt tggaactaaa cttgcctctc ctggtgttat agctatctta atatttctat
    46741 attcttcatt gggattatat ggtataaaat tcaagtgatt tattcctata ttatataaat
    46801 tagatattgt ttccaataca gtatgtttat tatcgtttac tactaataca tctattcctt
    46861 ctggcaatga gaataactta tatatatcct tttgttttat actcctattt atagttatta
    46921 tctttgagac atcttctaca tattttttta tttttaatac tctatcatct atcattacca
    46981 atattatgtc atcttttatc agctcctttt ctgttatttt atttaaataa taatttttta
    47041 tcattacttt atctttaaat atcatttcta gatttttatt taaaaaacat tctaatttag
    47101 acaatccatc agttactact gctattgttt tcattttatt actcctttta aaatatactc
    47161 tactctttta taatatacat ttgatttcca ctttaatagc ataaaaaatt gtacatttag
    47221 tatactaaca tattcattta ttagttttat ttccctaaac atcatagttg caatatatat
    47281 catatttctt aagcttatac agcaaaaaat gtgccaaatt aataattttc ttacttttat
    47341 tttaaagttc ttcaatcgta tttacagact tagcatttat aaattataag tctttatatt
    47401 attaatctat ttttataggt taattataca aatcatatac cacttttacc cattaaattc
    47461 attataaaaa agatggaata acgaattgtt actccacctt ttttgtaata aaaaattgta
    47521 tatataaaca ccatttgaca ctcttctaag tacaaacagt atctacatgc tataaccttt
    47581 caccattaga ttctattact tgtttatacc agttaaaact ctttttctta atcctagaca
    47641 agtctccact tccatcatca tacttgtcca catatataaa cccatatctc ttggccatct
    47701 caccagtaga tgcgcttact aaatctatac atccccatgg agtatatcca aacaaatcaa
    47761 caccatcttc tacagcttcc ttcatttgct ctatatgtgc tttcaaatac tctatacgat
    47821 agtcatcatt tatcactcca tcaggttctt ttttatcata agctcctaaa ccattttcaa
    47881 ccaccatcat aggtattcta tatctatcat aaatttcatt tagtgcatat ctaagccctt
    47941 tagggtctat ttgccatccc cattcactag actcaagata tgggtttttt actccaccta
    48001 atatattgcc acttgtatta ctttctttag actcactact tacacatgta gacatatagt
    48061 aactaaatgt ataaaaatct acacaacctt cttttaaaat ttctaaatct cctttttcca
    48121 tttttatctc aatattattt tctctaaaat atctattcat ataagttgga tattcaccac
    48181 gcacttgtac atctccacag aagtaattca ttactctatt atcttcttga gtcttaacta
    48241 catcatttgg attacaagta taagggtaca ttgttgcaaa tatctgcata catccaactt
    48301 gataatttga atctatttca tgagctaact tcacagcctt agcacttgct acaaattgat
    48361 gatgtaaccc ttgaaaacga agttgaggta tatctacttg gcttataaaa tctgtagttc
    48421 cttcatttaa tatcccttgt gacaagtacc ctcccatagg cattgtagct gaatttattt
    48481 cattaaatgt taaccaatac tttactttcc ctttgtatct tttaaatatt gcctcacagt
    48541 aattcatata caagtctatt acttctctcg aagcccatcc attgtatttc tctgttattg
    48601 caaatgggac ttcatagtga gatattgtta ttaatggttc tatattatat tttaagcatt
    48661 catctattac attttcataa aatttaagcc ctgcttcatt tggttctttc tccattccag
    48721 ttggaaatat tctagtccat gctattgaaa atctaaatac cttaaatccc atttctgcaa
    48781 ataaagctat atcttcttta tatctatgat aaaaatctat tgcttcatga cttgggtaga
    48841 acgttccttt ttctatagtt cttgttattc ttttacttac tgtttgagaa cctccagtac
    48901 acatatctga acaagatgta cctttcccat ctaaattcca tgctccttca cattgatttg
    48961 ctgctgttgc tccaccccat aaaaaatctt ttttaaatga catatctata tcctcctatt
    49021 ataattcttt accatttgat tctattactt ttttatacca gtcaaaactc ttctttttac
    49081 tacgttttaa agttccgttt ccatcattat ctttatccac atatataaat ccatagcgct
    49141 tcttcatttc tccagtactg gcacttacta agtctataca tccccatggt gtgtatcccc
    49201 acaaatcaac accatctaac tcaacagcat ctatcatagc ttttatatga gcacgtaagt
    49261 aatcaattct atagtcatca tttatattcc cagtttcatc tggattatct actgcgccta
    49321 atccattttc aactataaat aatggttttt gataacggtc atacaaagaa ttaatagtta
    49381 ttctaagccc tagtgggtct atttgccatc cccactcact tgcatctaaa tatggatttt
    49441 taagactttc aaaaacattt ccttctgtta aaatatttac ttcagggtct gcacttgtaa
    49501 gccttgatga ataatatgag aatgatataa aatctactgt gttctcttta agtatctttt
    49561 tatcatcttc ttccatcacg atatttattc cttttcgttc caattctttt aatgcataag
    49621 ctggatattc tccacgagat tgtacatcta taaaaaagta gttttcccta tctttttcta
    49681 tagatttcca tacatctagt ggattacaag tattggcata agtattcccc gctgctatca
    49741 tacaccctat tttaaattct tgatttatgt tatgagctag tttagtaact aatgcacttg
    49801 caactaattg atgatgtgca gcttgatatt ttatttgttc ttcattttct ccctcttcaa
    49861 tatagagacc tgcacctata aatggtaaat gaagtatcat atttatttca ttaaatgtta
    49921 gccaatactt tatcttatct ttaaatcttg taaaaataac ttcacaatat tttacatata
    49981 aatctactag cttacgattc ctccatgctc catatttttt tactaaatac attggaacat
    50041 caaagtggca gattgttact actggttcta ttccatactt taaacactca tcaaacaaat
    50101 cttcatagaa ttttagaccc tcttcatttg gaacttcctc aattcctgtt ggaaatatcc
    50161 tagtccatgc tattgacata cgatagcatt taaaccccat ctcagcaaat aattttatat
    50221 cctctttgta attgtgatac atatctattg cttcatgagc tggataataa tgctcctcat
    50281 cacattcaaa cattttcatt ttcccagtca aaactggaaa tctatctttt ccctgtggta
    50341 taacatcaac attagctaga cctctaccac cttctttata cccaccttca cattgatttg
    50401 ctgctgttgc tccaccccac aaaaaatctt ttctaagtgc cataactcta cctccaataa
    50461 tttatttata gtaaatttat tttaaaataa aaatacatat atctaattct caattaataa
    50521 agccgtcctt tacgctaaaa cagttatcaa ttcctgacta ttacttatat gcttttgtgt
    50581 attttctacg atatccacat aatcagaata atttgtaacg actactggag tttctaagca
    50641 atatccttct tttgatatgc tttctatatc aaaagttagt aatgtctgac cttttttaat
    50701 cttatctcct tgattgacaa aagatttgaa atacttacct tctaactgaa tagtatttaa
    50761 ccctatatgt atcaataatt cacaaccatt atcagatata attcctattg catgttttgt
    50821 tggaaataaa gtcattacag tcccatcaaa tggtgctact acttttcctt cttttggtgt
    50881 tattgctaca ccttttccca atacacctgt tgaaaatgct gcatcttgca tatgttccaa
    50941 agcctttact tcacctttta ttggactata tattacttct cttttgtttt tttctacagc
    51001 gcctttacta ttattatctt tggaaatttc tactatagta tcatctttcc aaagaaagaa
    51061 tgttaataca aatcccacca caatggctac tattatagat attgtcgttg cataaacacc
    51121 tgtcatatct ccagttgttg gatttatata attaggtata ccaaatattc caagtccacc
    51181 cattacataa ctttttacat tcattactcc cattacagct cctgctacag caccacctac
    51241 acaactgtat atgaatggtt ttttccttgg taaagttatt ccatatattg caggttctgt
    51301 tacaccacat attcctgaaa taattgcagg tatacacaac tccttcattt tcttatcttt
    51361 taatttaaag tacattgctg ccactactgc tgtttgtgca aaagatggta caaatgctcc
    51421 cactaatatt gtgtcaaatc ccatagtcat aaggtttgac atagctattg gtactagtcc
    51481 ccaatgtagc ccaaatatta caagcacttg ccacaataaa ccagttaatg cgccacatag
    51541 aattggtgaa aagttaaata aagctaaaaa tccatttcca actatattag aagcataggt
    51601 agctataggc cctataacca taaatcctaa tggtaaagaa actagtaaaa ctgccattgg
    51661 tacaaagaaa ttttttacta catctggtat tattttagca aacatttttt ctaacttaga
    51721 tgctaagaat actattaaaa ttactggaac tactgttgaa gtatagttca ttgctattac
    51781 tggtaatcct aagaaagtta tatatactgg tgattcaaat attgttcctg taaatagatt
    51841 gtataaaggt tgacctgttg atgccagagt gtccaattga atacctgaat agcacaaaac
    51901 tgcacctata agcataccga taaatggttt tagcttaaat ttcttagcag ctgtatatcc
    51961 aagaattata ggcatatact ggaacattgc atcaccaatt gcatttaaca taatatacgc
    52021 accatcagtt tctccataca aacccagtgc tgtaaatact gcattgaaac cttttatcat
    52081 accagcagca cacagtactc ctagtattgg ttggaaaact cctgatatta tgtctataaa
    52141 cttattaagt aatccttttg gtgaatctga acctgaatta tctattgtat ctcctcctaa
    52201 tccagccaaa tcacacacaa cttcataaac atctggaaca tggttaccaa taactacttg
    52261 atattgacct gtacttttca ttacagtaac tattccatcc atttttttta gtacatcatc
    52321 atttgctatt gactcatctt ttaacttaaa acgtagtctc gttatacagt gagataaact
    52381 gctaatatta tcctttcctc ctacattctc aatgatttct tttgatagtt gttcatactt
    52441 tctcattttt tatcctccat tttctttttg aaatatgaag gtttggccaa cttaatgtca
    52501 ccacccaata tatataaacc taattattag gatttatatc tgatttaata cttttgctta
    52561 ccaccctttc gacatgaata gttaagtata atttttcctc atctgttaaa ttgtaattgt
    52621 attttttatg tataaattca tctaactttt ctatgcattt ataagcattt ttatatttga
    52681 cttttattac ctttaataaa tcatcttcat tattttcatg taaattatta ctgacaactc
    52741 tttctgcaaa gtactttaag tgagtgataa atctatgata ataaactgaa tcttcatcaa
    52801 atactattct ataatggtac ttaaccacat ttgcgatttc ttgtattatt tgcgtaatat
    52861 catatataat ttttatactt tgatccattt gtgcattaac tatatgtagt gcaataaatc
    52921 ctgcttcatc ttctggcaat ctaatttcaa attttttttc tatataatct aaagccttta
    52981 aacctatgtt aaattcattt ttataaaatc tttttatatc ccaaagtaat acatttttta
    53041 catttactcc ttcacgagct ctttctattg cagtatacat atggtctgtt aaagaaatat
    53101 aaatactatc atttaatctt ttccctagtt tttctttagc atataaaatt atttcatctg
    53161 ataattccat atatttcata ggaatatctg ctattaattc tttaaattta tcacatatat
    53221 ttggatctga aagtttgaat atcttatcaa tcttatcctt tgatatatgg tctcctgtac
    53281 gttttttata agctaaacct cttcccataa ctactatttc cttatgattt tcatcagttg
    53341 taataattac attattattg agtatttttt caataatcat tttgatgcct cctttattag
    53401 cattaagtta aaataaatct tttttaatta tttagaatat ttaaaatgta atttattaca
    53461 taaaaaaaaa cctatttatt acacattgaa tagactccca tgagccctga gtaataaata
    53521 ggtttagctt gtatttaaac aatcactatc cgtttgtatt ttattttaat tattatttat
    53581 tatatgttag caaatttatt ttttagtgtc aactttttct taatatttta atttttaata
    53641 aactatataa attgaatcca caaaaatatt atttttatca ataatcaata taaaaaaagg
    53701 tattactttt tttaagtaat accaatttat ttttaattta agtgattttt tttaatctca
    53761 tcaagtagtc catcttctaa ataaatttct aatgcacatc ctaccattgc ctttactgct
    53821 ttgtgaagtt tgtcataagc ttcctcagaa tttgcatagc ttagaaactc tttttcatga
    53881 acatatacca ttggatttat atctaaagct atttctgtat acatagtagg acaaacttga
    53941 cttacattcc ctatgtctgt agaacctact ggaccatctt taccttctaa tatatctgtt
    54001 atacctgcct caatcaaatt attttttgtt atcttttgaa gaactttatt atttattatg
    54061 ttgtcaaaag aattttcaaa atatctataa gaaagcttcg ctcctgtcat taactctgca
    54121 ccttttgcac agtttataac ctttttagtt acttcatcta aataacttct ttcagcagct
    54181 cttacaaaaa acttacaggc tgctttttct ggaactatat ttggagcttc tcctccattt
    54241 gaaactattc catgtattct aacatctgat tttacatgtt gtcttagtgc atttatccca
    54301 gcaaaagtaa gttgtactgc atctagtgcg ttgactccca tatgaggatg actagccgca
    54361 tgtgctgata ccccttcaaa actaaactct aatgaatcta ttgccaaagc cttgcaattt
    54421 atattattaa aagcttctat atgcatttga taacttacat caacatcatc aaaagctcct
    54481 gccttaacta aatcacattt tcctcctgtt gtttcttcag ctggtgttcc tattagtaca
    54541 atttttcctt taaaattttc ttttaactta cttaatacta tacaagctcc tagtgtagat
    54601 gctgcaatcc agttgtgccc acaagcatga gctggttctt tattttctcc atatccagga
    54661 agtgcatcat actcagctaa aaatgctata gtaggtccat cattatttcc taattcagct
    54721 ctaaaagcag tctccatatt gcaatacgga taaattgtat caaatccata ttcctccatt
    54781 ttctctacta agtattttga tgatatatat tcttcttccc ctaattctgg attgttaaat
    54841 ataaaattac aaacttcttc aatttctttt ccaagttcat tctctatctc ataagctctt
    54901 ttctttatac tctctatcat aacttacctc ctactagaat cctagatata atcctattgt
    54961 caaaaatacc attacaagaa ctgtcaatgc taccattaaa ggaattatga atctaaccca
    55021 ctttgaccaa ggaatattgg ctactgctag tgctcccatt aaaacacctg atgtaggtgt
    55081 tattaagtta gttacaccta taccaaattg ataagctgta actatcattt gtctagatac
    55141 atctactaag tccccaagtg gtgcaagtac aggtattgta agtgatgcaa gtcctgatgc
    55201 tgatggtatt aaaaatgcta ttaatccttc tattaagaaa gttaaattta taaatatagt
    55261 ttttggtaat ccgtttaata aatttgctgc agaatttaaa attgtatcta ttataaatcc
    55321 attttctgct attattacga ttccacgtgc aaatgctata cacaatcctg ctgtcattaa
    55381 atctccagct ccacttataa atgaattaac tatatcatct tgtttaagac ctgatgctat
    55441 acctgatatt atacctatag ctgtaaatat cattgcaatt tcagttatat accatcccaa
    55501 ctttaaaact ccatatatca taatcgccat acctattgtg aaaattgcta ttaccatggc
    55561 ttctcttttt gtaaattctt ttatgtttga atcactatta accattgact cttgatttag
    55621 agatatatcg tgtactaaag attttttagg gtctttttta actttattgg catacatcat
    55681 aacaaaccct atagatatag ccatatatat tataaacata acaactctaa actctattcc
    55741 agaacctgga gttatttgtg ataatgcttg tgctattccc acagagaaag gattagtagt
    55801 agctgctcca aatccagctg ttgctcctat aaatactgtg gccactgctg tcaatgaatc
    55861 atatcccata ctggtcataa gtggaataaa tatcatataa aaaggtagtg tttcttcact
    55921 cattccaaat gttgttccac ctagtccaaa tagaatcatt gaaataggta ttattaaaaa
    55981 ttgaaacctc ttcattttat ttacggtatg agctataaca gcttctatag cccctgtttt
    56041 attaactatc ccaaaagctc ctccaactat taaaacaaat ccaactactt cagctgcatc
    56101 tataaatccg tttataggtg ctgtaaatac atcagtaatt ccttgtggat ttgatggtgc
    56161 tttttcataa gttccagcta caacaactga ccttccatct atatctactc tttcaaaatt
    56221 tccacttggt actatccaag taagaattgc cattaacact attagcaaaa atattattgt
    56281 aagtgtctgt ggcatagtaa actttttctt ttttaaactg ctcattttta atctccccac
    56341 tttttaaatt aaaatatttt attattgcat ccctttatcc tattttgtat agatgtaaaa
    56401 aagctcaaca tggatacatg ttgagctaaa tgtgctaaat acaacatacc tgcatcttcc
    56461 ctttatcttg tttaagatag ctctccatca aaattcggga taattttgat gacagtactg
    56521 tacctattaa atacagtccc agcactagct tcggacacta gtacttcggc acttactcct
    56581 tttatattgc ctcattggtt tccgacctct tcaatattaa tcttagtaaa tgcaacctct
    56641 acctcaatct ttttattaga tgaggtaatt cttattaatt tttattaatt caaagtaatt
    56701 gtagcataat atgtcgagat tgtaaatatt ttcagtataa taattcttac tttatgatat
    56761 gattcaattt ttcacaaata attttttctc catataattt aaataatgta gcatattttg
    56821 aatacacaca aattttccat gaatttcaaa ttattttaat acccttataa taaaaaatta
    56881 aagccatgta aacttatcaa tttacacggc tttatataca ttaatctaca ccaagtaccg
    56941 ctttgagttt tgatgctatt gtaataactc gtggtccaaa tataacttga actgagtttt
    57001 tctttttaac aactccactt gcacccaatt catttaccca gaaaccatca tcatagaatc
    57061 catcaattga atttaactct accctaagtc tagttgcaca gtttgtaaca ttttttatat
    57121 tactacttcc tcctaaacct tctattatag agtgtacaag ctctgtatct ttatcatcta
    57181 cttcatctcc tacagcattg ttatatactg ttttaccagc atctacagat tgtttttctc
    57241 tatattcttt cttgctataa agcttaactt cttctgaact tcttcctggt gtctttatat
    57301 caaacttctt aattgcccat gtaaatatta tataagtaac tataaaaaat attggtatca
    57361 aaaataataa tggtaatgca tccacttttt ggggttgcaa tagattagga aacatatttc
    57421 taaatgattc ccccattata gaaacattaa acatttctgt aaatacatac gtcaatcctg
    57481 ctagtggtac atatgctaaa aagtacaata atggtgcaac aaataagaat gtatactcta
    57541 ttggttccgt tactcctacc aacatggctg ttactattgc tggtattaat atacttattg
    57601 cttttttctt attgacatta tcagccaact tatacatagc taaagctgct gctggtaata
    57661 ttgcaaaatg tattaataaa cgtcctgttg tgaagttacg agttatataa gatagtgtat
    57721 ctgggtctcc catttgagct aatcttatat tgttaacacc ctcgtaaatt gctccaccta
    57781 cttccattgt tccaccaact cttgtatatt ctataggaaa tgcaattaag tgatgtatac
    57841 caaatggtaa taatgcttta tccattgctc caaaagtaaa tgttcctaat aatccactag
    57901 aacctatcca attaccaagt ttagataatg ccaaccctac tggtggccat ataaagtaca
    57961 ttgctgtacc caatactatt gatgctataa acatcataat cattgaaaat cttggtcctg
    58021 agaaaaaaga taatgcacta ggaagttcta tgtcaacaaa tttgttatgt actgcactag
    58081 ctacaaatcc agctattata gctccaaata tactacaatc atatgaaaat attcccaaga
    58141 aagaaccata taaggaactt cgactatatg cttctgcctc gcctaatcca gatgccataa
    58201 acgcttctgc tgtaactgta tctgaattta taccatttgc tgctagcaat gtacttataa
    58261 ctgtgtgcat tcctataaat aaaacaattc ctcctaatgc accccatcct ttttcctttt
    58321 tagataatcc aaaagctata cctgtaacaa agaatattgg taaatatctc attaccataa
    58381 accctaggtc gtttattact ttaaagaata catttataaa tgacccttct tttattattc
    58441 cgctaagccc taatgcataa acgttttcca tatttgcaaa agctgaccct aaccctataa
    58501 atactcctgc tacaacaagt aatataacag gaatcatcat tgctccagaa agtacttgta
    58561 atttatcctt catagtatta tttcctccat ttttattgaa atgccaggct atataatgca
    58621 tatatatata cttctattgc tttgtataat gtatctatac ttatattttc atttgcctga
    58681 tgtgaatttg gattatctcc ctctattgtg ggtccaaatg caactccatt ttctaatact
    58741 cttgcataag atgcagctcc ttttgtaaaa agttctgcct ctttttcaaa accttgttta
    58801 tatgcacttg ataatttatt tattaattca ctatctggtt ctacatacag taattttaaa
    58861 ttcttatata tatcaattat taaattttct ttttttccaa tttcattaat tctattagtt
    58921 ataaactcca aacttatacc cttaggatat ctaaaatcta ttttcatatt caattcattt
    58981 ttatctaaga agatactcat tatacatatt gtagaaacgc ccatatctac atcttcttta
    59041 tatatcccta ttttttttcc atgattatca tctgtaaagt atgaatttaa aatatccttt
    59101 attataactc ctttatcgtt tagcccttta attctctcta aatcttttgc taaactaaat
    59161 gcacagttat atgacctgtg tggatttctc gacaaagctc tttctcctgt atatcttact
    59221 aatacttttc cttcttctac ttcttctatt tctgtataat aagctaatga ttctactaaa
    59281 tctttcttat tattagtttt aaagacagcc tcaattttgt cacatacaaa tccatcttct
    59341 ttgtttgact ttatatcaac taaattgtga tttctaaatt tatctttatc tattttcttt
    59401 cttagattga agtataaaat acctttttct ccatttacta ttgggaagtt tccatctgga
    59461 gaaaatgcaa attttggctg ttcatttaca ctaaaataat gttccataca ttcccaagtc
    59521 gtctcctcag ctcctcctac tatcaatcta atctttctct ttggcttttc attaagttct
    59581 cttaagaaaa gtaatgcata taaaatccct atcaaaggtc ctttgttatc attaactcct
    59641 ctaccataaa gatagttatc tttttgacat actttaaaag gtttactctt ccaaagttct
    59701 ttattatata ttggcaccac atctatatga ttaagcaccc ctactacttc ttctccttct
    59761 ccatattcta tatgaattgc atatccatca aaatctttta caacaaaatc tttgtctttt
    59821 gctattttaa taagcttatc gaaggcattt cttatttcta tcccaaatgg ttgatttata
    59881 tctgttgtac tttcatctct aattgaaggt atttcaacta aactcctaat atcctttatg
    59941 atattttctt gattggattt taaataatca ataattagtt ctttatttac tatcatctta
    60001 attatttatc acccctttat attagtttta caaagcattt cagttcatat ttacattata
    60061 aattttgagt attatttttt caatatttca aatacttctc taaattacca taatgatacg
    60121 gtaaataatc aacagattat gacaaaatta tactatacct actattaata ttttatctta
    60181 tctattacat cttttttaat gtaattttat tccattaaat gatattaaaa gtaaaacatt
    60241 agagatattt taaatatata aaaaatggat gtaggtaaat ttatttttat gtaaatctac
    60301 ctacatccca tgattttatt aaacaattat attataatat tcatatctat gtgttctata
    60361 cctttaatag ttatagcttt atctaatact ttactaatca actaattaaa ttcaaaagat
    60421 tttcttttaa ataacattct aaattaagtt acataaatct tgaataaatt gcctctgtta
    60481 ttaaaacatc tgaccccata atataaaata aatacataca ctttacaaca ttttaatttt
    60541 gtaaatacta atttcatgta tataagataa atttcctatt aatattaata aa
//
LOCUS       DAMKOJ010000013        60207 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000013 DAMKOJ010000000
VERSION     DAMKOJ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 60207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.014"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            389..3043
                     /gene="adhE"
                     /locus_tag="PC592_000925"
                     /gene_synonym="adhC"
     CDS             389..3043
                     /gene="adhE"
                     /locus_tag="PC592_000925"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF4054932.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIKEAQKI
                     FATYTQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDESADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMDKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     VASFLGLKGNSEEEKFQSLLSAIEDLKFKVGIPKTIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3319..5538
                     /locus_tag="PC592_000926"
     CDS             3319..5538
                     /locus_tag="PC592_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4054933.1"
                     /translation="MTRRSKSFTLIIILFLTSLFLTMGYIYIEDTKNLLMSEAKIHIK
                     EVAIQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDELENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYADEVNKSIKKITISVPLLNNDK
                     VVGVLYCTYNINTLMKLINVSFYENNSISYVVKNDGTVILHPQEDSISKNIYKLLKQD
                     NDIREVNSLKKELQENKTGATVLKMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSEKIINRAIYAVLFIILIFIAIIFYIIYIKKSNEKEILSLAYEDKVTHIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVFARLSSDYFAIFCDYKNGRNKIIRKLDSIRNNIESNLSIVFEISLCVGIYFVEED
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVNGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFEKVCTD
                     LSEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIQMYNLSSDLIEIEITETVAINE
                     LNILKNVLNELRKYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLDGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            5792..6454
                     /locus_tag="PC592_000927"
     CDS             5792..6454
                     /locus_tag="PC592_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054934.1"
                     /translation="MIDVSIDKKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TLNKNLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSEESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6824..8233
                     /locus_tag="PC592_000928"
     CDS             6824..8233
                     /locus_tag="PC592_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDF4054935.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGILFVAYIGMAIFFRNHFYF
                     GTTINGVRASGKTVEQVNDLLTSSTNSYTLNLDERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMVTLSYNKDLLEKRFNALSCLDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEVPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKNITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNRDDIGNTYVEISLSNQHMWFFKNGEMLVSTDIVTGNLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGGIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8348..8623
                     /locus_tag="PC592_000929"
     CDS             8348..8623
                     /locus_tag="PC592_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054936.1"
                     /translation="MNEKLTKILEKAKNDDEFRKELIKSREQRDVMDSFCKVVTSRGY
                     DITVGELFSIGEEYTSNLLKSVNGGATYPIEDWSDWYEDFFIMLSNI"
     gene            9253..9564
                     /locus_tag="PC592_000930"
     CDS             9253..9564
                     /locus_tag="PC592_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054937.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAKERKSKAIEAVIGKVV
                     R"
     gene            9566..11491
                     /locus_tag="PC592_000931"
     CDS             9566..11491
                     /locus_tag="PC592_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDF4054938.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEEQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDGLRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHAESIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIALVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGVLGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            11494..11985
                     /locus_tag="PC592_000932"
     CDS             11494..11985
                     /locus_tag="PC592_000932"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDF4054939.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            12037..12600
                     /locus_tag="PC592_000933"
     CDS             12037..12600
                     /locus_tag="PC592_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HDF4054940.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            12615..13592
                     /locus_tag="PC592_000934"
     CDS             12615..13592
                     /locus_tag="PC592_000934"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HDF4054941.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKVMSSAILEAFDVYSKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            13579..13902
                     /locus_tag="PC592_000935"
     CDS             13579..13902
                     /locus_tag="PC592_000935"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDF4054942.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            14019..15797
                     /locus_tag="PC592_000936"
     CDS             14019..15797
                     /locus_tag="PC592_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDF4054943.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTIKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            15794..17167
                     /locus_tag="PC592_000937"
     CDS             15794..17167
                     /locus_tag="PC592_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDF4054944.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            17173..17841
                     /locus_tag="PC592_000938"
     CDS             17173..17841
                     /locus_tag="PC592_000938"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDF4054945.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDAAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSAAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            18118..19167
                     /locus_tag="PC592_000939"
     CDS             18118..19167
                     /locus_tag="PC592_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF4054946.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADVIWGLSAMNMIELKE
                     DGALEAYKPKHYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGAKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPVEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYSHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLSSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            19263..20252
                     /locus_tag="PC592_000940"
     CDS             19263..20252
                     /locus_tag="PC592_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4054947.1"
                     /translation="MSYLKIKNVFKNYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGDIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKISKEKIDNKVKEVLEIVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            20257..21975
                     /locus_tag="PC592_000941"
     CDS             20257..21975
                     /locus_tag="PC592_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF4054948.1"
                     /translation="MNNNAIGYKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASETLLNSLKNTIFVSVISTVISLALALVYAYALTR
                     TNLKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGIHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLNSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGIVGIIAFGIISVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFDFMDTIYLKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILITNILVKAIHEFIKNRLE
                     KRTNFN"
     gene            22403..23134
                     /locus_tag="PC592_000942"
     CDS             22403..23134
                     /locus_tag="PC592_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HDF4054949.1"
                     /translation="MGRAKYYDIYIDLKNRIENKEYLYQDLLPSEYTLIEEYNCSRNT
                     IRRAIQELANQGYVQSKHGKGVFIIYKANKQSEFLLGGTESFKESAIRNKKEYKTKVV
                     HFEEMVIDDKKSQITNFEVGTEVYYIQRVRILENKPSIIDHNYFMKDIVKDINEEIAS
                     NSIYEYMESELNETIVTTKRTMTVEKATKLDKKYLELGDYNCVAVVSNNTYNAQGIMF
                     EYTQSRHIPDGFIFFHQSQRINNIK"
     gene            complement(23150..24907)
                     /locus_tag="PC592_000943"
     CDS             complement(23150..24907)
                     /locus_tag="PC592_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054950.1"
                     /translation="MKGLYQMNIKEIPFSYFGSYMSISYSDELGFTLKSLRGKSKKNM
                     DVLRIIPTVNNMPVDYEFEANYFSILIKFNNGSISICFEGDSKIVFYGKGKNVGLKLD
                     TLPIYNFEYNYLMGKKGSEYCVINSYKNLTKFLVFSVNGKVGLSQNIFIDDCASTNKA
                     NNTSIIDVKSNSDNEFICVIEDIPTHMKVPDYKEYNFETSLNSTKKLFDEYYLAQPKV
                     DEKYKNSLLKASYINWSSFVKPQGYLKRYTILASNSTFLGAWSWDHCFNALALAGVND
                     KLAFDQMAVLFDYQDEYGQIPGSLSDSTIRWNFTKPPIQGLFFSKMMKKINFTKETLE
                     KIYNYIEKQVLFYVKFKDSNMDGIFEYHHGNDSGQDNSTIFKGAMVVDTPDLTAFIIN
                     AMDMLSKVAEKLNRNSEKEYWSNKADELTKLFLNYFIVDDLPVARETVTGEILSNNAL
                     LPLVSLVLGNRLPKYIRDKMIDLVTSERYLTKWGIATEAIDSDEYQDDAYWRGPIWAP
                     TTLLFVEALEECGENELAIDIAKRYCELVDKNGFAENFNAITGEGLRDKSFTWTASTF
                     IYLAAKVYEYNSQRINNIK"
     gene            25137..26570
                     /gene="treB"
                     /locus_tag="PC592_000944"
     CDS             25137..26570
                     /gene="treB"
                     /locus_tag="PC592_000944"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HDF4054951.1"
                     /translation="MRKNKILNSKESISKIIEYVGGKENIQSATHCVTRLRLILKDTS
                     KANISKLEDIDIVKGCFNAGGQFQIVIGTGVDKVYKDLIDQTGAEEVSKEEIKQQVNE
                     KSNKFQKFIRILADIFIPILPAIVASGLLMGVNNMIANPGIFYEKSVIEVNTDIAGIS
                     GIINLIANTSFTFLPALIGWSAAKKFGGNPLLGVVLGLVLVHPALMSAYDFAANPSAA
                     PTWDIFGMKVAQVGYQGQVIPVLIATYILAKLELFLKKTVPDAVQLVLVSPIALLITG
                     MLTFVVIGPITMTGANMITNGVVYLFEVAPVFAGALYSFISPPLVITGMHHLFLGVNL
                     QMAGTLGYVTLWPISETVTLAQGAATLAMFFILKNNKNLRGVSITSTISAWLGITEPA
                     IYGINLRFRYPFIAVMVASAIGGAFISYHNVKATAVGVGGVFSFLSVMPQYWGVYFTG
                     MAITFVITIGLTYLFYKSGKFKTNDNI"
     gene            26633..28291
                     /gene="treC"
                     /locus_tag="PC592_000945"
     CDS             26633..28291
                     /gene="treC"
                     /locus_tag="PC592_000945"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF4054952.1"
                     /translation="MLDFKKSIVYQIYLKSFNDTTNNGLGDLNGITEKLDYLEFLGVD
                     YVWITPFFVSPQNDNGYDVADYYNIDPIYGTMDDLENLIKEAKKRNIGIMLDMVFNHT
                     SIENEWFKKALKGDEYYKDFYIFKNPKEDKSAPTNWESKFGGNAWEFVEEFNQYYLHL
                     FDKTQADLNWENPNVRKELKNILKFWIDKGIKGFRFDVVNLISKPEKYEDDLQDDGRR
                     FYTDGKKVHQYLKEMCEESGILENDMLTVGEMSSTTIENCVKYSNPDEKELSMCFNFH
                     HLKVDYKNQNKWMLQDCDFIKLKKILNEWQIGMQKGNGWNALFWCNHDQPRIISRFGD
                     DKKYYKESAKMLATMIYLLRGTPYIYQGEEIGMTNACFTNIKQYVDVESLNYFDILKS
                     KGMKDGEIYNILQERSRDNSRTPMQWNNSKNAGFSESKSWIEVINNYRNINVENSLKD
                     KDSIFYYYKKLIALRKKYDVVAYGDFRPLLEEHDSIFAYKRCYEKESLVVLNNFYDKE
                     IDVVLENEELEKYKCIISNYGDRKIVSTITLRPYECIALFKNEK"
     gene            28544..29248
                     /locus_tag="PC592_000946"
     CDS             28544..29248
                     /locus_tag="PC592_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4054953.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVLANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADEELSGKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCAYKIAMSEREVQAVISNKECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            29448..29759
                     /locus_tag="PC592_000947"
     CDS             29448..29759
                     /locus_tag="PC592_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4054954.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            29781..31094
                     /locus_tag="PC592_000948"
     CDS             29781..31094
                     /locus_tag="PC592_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4054955.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQAGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            31171..32481
                     /locus_tag="PC592_000949"
     CDS             31171..32481
                     /locus_tag="PC592_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF4054956.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEDG
                     KEKLEIVGNLAKRMVKKAGIDMQINLTLDRREALKDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVEGDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNNGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPKFNR"
     gene            32507..33238
                     /gene="chbG"
                     /locus_tag="PC592_000950"
     CDS             32507..33238
                     /gene="chbG"
                     /locus_tag="PC592_000950"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDF4054957.1"
                     /translation="MTKIIINADDFGYCEAVNYGIVSVHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKSLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDYDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLISLKPVIEKIVNKYNLPIRGGFEYNLEYSK
                     IVPLIDSFYKENVCEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLDKNDLVISSYRDI"
     gene            33251..33568
                     /locus_tag="PC592_000951"
     CDS             33251..33568
                     /locus_tag="PC592_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF4054958.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(33690..34154)
                     /locus_tag="PC592_000952"
     CDS             complement(33690..34154)
                     /locus_tag="PC592_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054959.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     KDELLYFMEKGTAKISAKAIVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIIEKIEDVVVGTSIPYNYEKSKF"
     gene            34423..35361
                     /locus_tag="PC592_000953"
     CDS             34423..35361
                     /locus_tag="PC592_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4054960.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNAEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPIATANVDSYETDKLPSYIREELKDVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSRL
                     FDKEEETKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMISMEGLTDIDADHIVVIATESDKKDLENSAIWAQIRAV
                     KDGNVTILDSAPFFSQSYNPMGKELLLESVKNELTK"
     gene            35490..36503
                     /locus_tag="PC592_000954"
     CDS             35490..36503
                     /locus_tag="PC592_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF4054961.1"
                     /translation="MTKVSKKNITYLLILVSIVVLVFGILLSITIGAKDMNLSTVIDS
                     LIKMEDGINIRIVRDVRLPRAIAATLVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFTISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVNWEGIKLLFIAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNIVRFVCIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            36509..37531
                     /locus_tag="PC592_000955"
     CDS             36509..37531
                     /locus_tag="PC592_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF4054962.1"
                     /translation="MKNIIKINSKTLLVILILVVLIFITLLVSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALVGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSVWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            37546..38328
                     /locus_tag="PC592_000956"
     CDS             37546..38328
                     /locus_tag="PC592_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4054963.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPKSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMDDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDIV"
     gene            38340..39680
                     /locus_tag="PC592_000957"
     CDS             38340..39680
                     /locus_tag="PC592_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4054964.1"
                     /translation="MENQEALRHEKIWILLFKYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLIFLEDMLFILGASKDSISYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVTHYFMR
                     GKSNLKLKICNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKKYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDPDLMNIAVRGININLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPIADFIAMIIVLLFLKREFKTSQV"
     gene            complement(39771..42053)
                     /locus_tag="PC592_000958"
     CDS             complement(39771..42053)
                     /locus_tag="PC592_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4054965.1"
                     /translation="MNFENTKNKKIIATLLLTLLIIVSLTCVTFIMNLNKVTHNETER
                     YLIEISQSISTTIDVKCKSIFKTLYSVGDTYFEVNDSDKEVNKYLSKKLKLFEFDWLG
                     IINSNGNFISALKDTGNVKGQDFYIKALQGKETITPVKSPFGTYGILYSVPLYKDDKI
                     VGAVAAWNTIDTMRNLLSVESFNGEGFSQIIDQNGNFIVSSANKNAPKNVVNFFDMIE
                     HKGKQVDKNKLDEMKTNLKKNKTGSMYYTLDDGISKAMHYIPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAILINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDMEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLKPEE
                     LLCRVSNDQFNVLIKTIPQKEILSYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQEPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMIRNKYDIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHIIESIVNLTKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKTLEETSMDSFVK"
     gene            complement(42383..43546)
                     /locus_tag="PC592_000959"
     CDS             complement(42383..43546)
                     /locus_tag="PC592_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF4054966.1"
                     /translation="MKLMGYLRENGQFGIRNHVLVIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKDLSSEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVGKMAREVSKEVRVEFDMSEIILALECGGSDPTSGI
                     ASNPSIGVASNLLIDEGGSSILSETTEVIGAEHLLATRFEDGKMKDKFLKFVSDVEKR
                     AITMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADTVPTDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEVFNEIVEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            complement(43559..43834)
                     /locus_tag="PC592_000960"
     CDS             complement(43559..43834)
                     /locus_tag="PC592_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF4054967.1"
                     /translation="MNIIIHANEKDNLVTCVRPLVKGEKISIDGKSYIVNDNIPVFHK
                     MATENVKKGDVVYKYGEVIGIATVDIKAGDYVHVHNIESTRGRGDKK"
     gene            complement(43855..44829)
                     /locus_tag="PC592_000961"
     CDS             complement(43855..44829)
                     /locus_tag="PC592_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF4054968.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVYPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGNPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVILGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKAIFKTNKNIEVN"
     gene            complement(45099..47012)
                     /locus_tag="PC592_000962"
     CDS             complement(45099..47012)
                     /locus_tag="PC592_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4054969.1"
                     /translation="MKSGGIIMKEILVIAPTKGTYEKSIHIVRKNKYTNIDVMFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSDEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVIDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLNKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGSNKVIPIDVKIICASNKDLKNLMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSNKYNKTPLIITPNIKKALLQREYEGNIRELEGIMERAVIVESFDSIL
                     LEKDSNEYTNNIVDKNNTDFEYNNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIENDV"
     gene            complement(47188..48402)
                     /locus_tag="PC592_000963"
     CDS             complement(47188..48402)
                     /locus_tag="PC592_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF4054970.1"
                     /translation="MNQEYVKGKPIFTNINKIPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CASALEELDTFIELYGNKCDYARRDTLLYTANKLEIKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIEDETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNKNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            48646..50028
                     /locus_tag="PC592_000964"
     CDS             48646..50028
                     /locus_tag="PC592_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF4054971.1"
                     /translation="MLSKDIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVNIMKVAYKSAKEFSSDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPAQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDKPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDVLMNIDMVGNNLKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            50040..51389
                     /locus_tag="PC592_000965"
     CDS             50040..51389
                     /locus_tag="PC592_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF4054972.1"
                     /translation="MELKSFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     QYNAVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMFIGFVVPIIEDNEQKYDGIGYNIASSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILFNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIMQDIGEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEVIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            51539..52072
                     /locus_tag="PC592_000966"
     CDS             51539..52072
                     /locus_tag="PC592_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF4054973.1"
                     /translation="MSDAHYNMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDEKHRELNEMWVNISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGDSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            52156..52965
                     /locus_tag="PC592_000967"
     CDS             52156..52965
                     /locus_tag="PC592_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4054974.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LKYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFDDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFDYSGHAIFYDELKLFNQEFLQFLEE"
     gene            53376..55421
                     /locus_tag="PC592_000968"
     CDS             53376..55421
                     /locus_tag="PC592_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4054975.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCSIDNLIYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIIHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KIIDINTVIEIFTKLNISIDKLHIIKEKYDEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASIDKLGKFIYCNKVFSNLIGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKDISAIQVLEDKIQNKFQAKGFVSKYTFESVVG
                     ESKIIKEKINIARKIAITDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYEEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDISLISKYFLDEINSNKCFTEESMKALKLYEWPGNVRELKNLVYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSVETWNNKNILLGRNKL
                     QEILKEKGIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYIKFKGVI"
     gene            55682..56881
                     /locus_tag="PC592_000969"
     CDS             55682..56881
                     /locus_tag="PC592_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF4054976.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     SRVKSIVDEKIFISLHEHPVLFPEYLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     ATKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGRNILR
                     VLKQVWK"
     gene            56933..57628
                     /locus_tag="PC592_000970"
     CDS             56933..57628
                     /locus_tag="PC592_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF4054977.1"
                     /translation="MDYLKLANHPLLWIASTIAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCILEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            57641..58318
                     /locus_tag="PC592_000971"
     CDS             57641..58318
                     /locus_tag="PC592_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054978.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNIIILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            58483..60084
                     /locus_tag="PC592_000972"
     CDS             58483..60084
                     /locus_tag="PC592_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF4054979.1"
                     /translation="MMYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDYKINGNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKYWNNFTEYCDLISKSGISINMGFLLGHGTIRWSV
                     MGGSKDRHPTEEEKNEITNIINDGMKSGAFGISTGLAYIPSKYADIDELVDIAKQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVD
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALKNEEGRALILKEAFIL
                     GDRGSIILLNTKDIDMEKKSIREIAIQKDIDEDKLLLDLLLDGDEELIFCLGGMYRSD
                     FPDKLHDNKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFSIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIEIENYSYPRSEDIDFSKPQSLAKGVEY
                     VIVNGKIALEDGNITENKCGEVLRR"
BASE COUNT        22561 a         7196 c        10473 g        19977 t
ORIGIN      
        1 ctttttgtat atttaactat atttacttta acttgttaat caagttatta ttttcatttt
       61 caagtatttt tatttttaaa cttgatacag caccatatta aaaatcattt ttataaagtt
      121 ttatttgtaa aaaatacaaa aatataaacg ttaaaaaaat aacgttatcc ttaagttttt
      181 agatgatttt attagtaatt tacgtaaaaa ataaagtgac atctagttaa attaagtatt
      241 tgtaaagcta gatattatta gtataaatga tgttatatta gataaaaaat aaaatgttaa
      301 aaaaataact tgaaaataga aaaagtgaat gctataatgt taataaatta acataataaa
      361 taaaaaacta tctcaggagg ttgttaaaat ggctcataaa gaacaagtaa taatagaaaa
      421 taaaaaagaa aatgaagtta tgtcagttgg tttagatact gtaaataacg ttgaaagctt
      481 agttaaaaaa ctagcaaaaa tcaaagaagc tcaaaaaata tttgctacat atactcaaga
      541 gcaagtagat aaaatttttt tagcagcatc tttggcagct aataagcaaa gagttcctct
      601 agctataatg gcacaaaaag aaactggtat gggaattgct gaagataagg ttataaagaa
      661 tcattatgcc tcagagtata tatataatgc atataaagaa actaaaactt gtggtgttat
      721 agagaaagat gaagcatttg gtatgactaa aattgctgag ccaataggtg ttattgcagc
      781 agttgtacct acaactaatc caacttctac tgctatcttt aaagcacttt tagctttaaa
      841 aactagaaat ggaataattt tctctccaca tccaagagca aaaaattcta ctatagaggc
      901 tgcaaaagtg gttcttgagg ctgctgtttt agctggagct cctgaaggta taataggatg
      961 gatagatgag ccatctttag aattaactac aactgttatg aaagaggtgg atttgactct
     1021 tgctacaggg ggtcctggga tggttaaatc agcatattca tctggaaaac cagctattgg
     1081 agttggtgca ggtaatactc cagcaataat tgatgaaagt gcagatataa aaactgctgt
     1141 aaactcaatt cttgtatcta agacttttga caatggtatg atatgtgctt ctgaacaatc
     1201 agttatagta ttggaaaata tatataatga agtcaaaaaa gaatttaaag agcgtggtgc
     1261 ttatttatta gataaagatg aaacagaaaa aataagaaat ataattttag taaatggagg
     1321 attaaattct aaaatagttg ggcaaacagc ttgtactata gcaaaacttg caggatttga
     1381 agtcccagta gatactaagg ttttaatagg tgaagtagaa tcggttgaaa tagaagaggc
     1441 ttttgctcat gagaaacttt caccagtgct tgcaatgtac aaggcaagtg attttgatga
     1501 tgcagttaga aaagcagaaa aattagtaga agatggtgga tttgggcata catcttcatt
     1561 atatattgat gatgtaaatc aaagagaaaa acttgataag tttacttcag ctatgaaaac
     1621 ttgtagaatt ttaattaata ctccttcttc tcaaggtggt ataggggatt tatataattt
     1681 taaactagct ccttctctta ctttaggatg tgggtcttgg ggtggaaatt cagtatctga
     1741 aaatgtagga gttaagcatt tacttaatat taagacagta gctgagagga gagaaaatat
     1801 gctttggttt agagcaccag aaaaagttta tttcaagaaa ggttgtttag gagtagcatt
     1861 aaaagaactt aaagatgtaa tggataagaa gagagctttt attgtaacag atacattcct
     1921 ttacaataat ggatatacta aagcagttac tgacttatta gatgaaatga atattaagca
     1981 cactacattc tttgaagtag aaccagaccc aactttggaa tgtgctaaga taggtgctaa
     2041 agctatgaga gaatttaatc cagatgtaat aatatctata ggtggaggaa gtgcaatgga
     2101 tgcaggaaag ataatgtgga cattgtatga gcatccagat gtagatttcc aagatttagc
     2161 tatgagattt atggatataa gaaaaagagt atatacattc cctaaaatgg gtgaaaaagc
     2221 taactttgta gctataccaa catcagcagg tactggttca gaagtaacac catttgctgt
     2281 tataactgac caagatacag gggtaaaata tccattagct gattatgaat tgatgccaaa
     2341 tatggctata gttgattctg atatgatgat gaatatgcca aaaagcttaa catctgcttc
     2401 tggtatagat gccttaactc atgcattaga agcatatgta tctatgcttg caaccgatta
     2461 tacaaatgga ttagctttac aagccattaa gagtatattt gaatatcttc cacgtgcata
     2521 tgacaatggt gcaaaagacc cagaagctag agaaaaaatg gcaaatgctt ctacaatggc
     2581 aggtatggct tttgcaaatg catttttggg tgtttgtcac tctatggctc ataaattagg
     2641 tgctttccac catgtaccac atggtgttgc aaatgctctt ttgataacag aggttatgaa
     2701 atttaattct tcagacgcac caaagaaaat gggagcattc tctcaatata aatatccaga
     2761 agcattaaag agatatgctg aagtagcttc attcttagga ttaaaaggaa attctgagga
     2821 agagaaattc caaagtttat tgtcagctat tgaagattta aaatttaaag ttggtattcc
     2881 taaaactata aaagaatttg gagttgaaga atctaagttt atggactcaa tagatgaaat
     2941 ggtaattcaa gcatttgatg accaatgtac aggagcaaat ccaagatatc cacttatgaa
     3001 tgaaataaaa gatatgtatt taaattcata ttatggaaga taaatttact ataaaatagg
     3061 aaaaataaaa attcttatac ataaaacaaa gttttattgt ataagaattt tttttgattg
     3121 gaaaaatgta tagtttttat tctttaattt aaaattcaat taaatagtgt tattataata
     3181 ataaaagaat gtttttatgg ttattaggtt gattttatgt gtaacattta agaatagtta
     3241 ttacaatata aatgatgaat tggtataaaa aggatatatt atctatatga agtattgact
     3301 aattatggga ggagtcgaat gacaagaaga agtaagagtt ttacattaat tataattctt
     3361 tttttgacat cattattttt gacaatggga tatatttata tagaagatac aaaaaatctt
     3421 cttatgtcag aagcaaaaat acatataaaa gaagttgcaa tacaaggctc tcaactagca
     3481 caaagacaga ttgaaaaaga tttagatgtt ttaaatattt tttctaacta ttatgcttca
     3541 aatccagaca tacctaatga ggaaaaaatg aagaatcttt tggatgagtt ggaaaatcaa
     3601 aaattttaca ctatggcaat agttgatata aatggtaatg ctgaaaatac caaaggtgat
     3661 aagttttcag tgaaagatag agaatttttc aaaaactcaa ttaaaggtaa aaagtatgtt
     3721 tcaagtccat atgctgatga agtaaataag tctataaaga agattactat ttcagtgcca
     3781 ttattaaata atgataaagt agttggagtt ttatattgta cctacaatat caatactttg
     3841 atgaaactta ttaatgtatc tttttatgaa aataatagta tatcttatgt tgtaaaaaat
     3901 gatggtacag ttattcttca tccacaagag gatagcatat caaaaaatat ttataaattg
     3961 ttaaaacagg ataatgatat tcgagaagta aatagcttaa aaaaagaact gcaagaaaac
     4021 aaaacaggtg caactgtatt aaagatgttg gaagaaagaa gatatttagg atatgctact
     4081 atggataatg ggaatagtga aaataactat ataaaagatt ggaatttgat tttttcaatt
     4141 ccagaaactg ttgtgtttag taattcagaa aaaataatca acagagctat atatgcagtg
     4201 ttatttatta tattaatatt tattgcaatt attttttata taatttatat aaaaaaatct
     4261 aatgaaaaag aaatattaag tttggcttat gaagataaag ttacccatat aggaaatcaa
     4321 aataaatttt atagagagtg tagtaagtat cttttagata aaccatcttt aaattatatt
     4381 atagtatatt ttgatattaa taactttaag atgattaatg atacttttgg atatgaattt
     4441 ggtgacaact tattaattac gatagcaaaa gctttaaaag aagaactgac agaaggggaa
     4501 gtatttgcac gactttcaag tgattatttt gcaattttct gtgattataa aaatggaaga
     4561 aataaaatta taagaaaact tgatagtata cgaaataata ttgaaagtaa tttgagtata
     4621 gtctttgaaa tttctctgtg tgtgggtatt tattttgttg aagaagatga agtagatatt
     4681 caaaaggctg taaataaagc aaatatggct aggtctgttg ctaaaggtaa aaatataaat
     4741 tatgctattt ataatgaaga tgttaggaat aagcttagtg aagaatcaat gattttagat
     4801 gatataaaaa tagcattggt aaaaaatcaa tttgaagtgt attatcaacc taagttttca
     4861 cttgtaaatg gagaaatgat agggagtgaa gcactaataa gatggaatca tccagaacat
     4921 ggttttataa gtcccgcagt atttattcca atagcagaga aaagtaagtt gattttaaaa
     4981 attgggagat ttgtatttga aaaggtttgc actgatttat ctgaatggaa aaaacaaggt
     5041 aaaaagatag ttccagtttc agtaaattta tctagagttg aattgtatca accagatatt
     5101 gtaaaattta tcaataaaac aatacaaatg tataatctaa gttcagattt aattgaaata
     5161 gagataacag aaactgtggc tattaatgag ttaaatattt taaagaatgt tttaaatgag
     5221 ttgaggaagt atggattttc tatttctatg gatgactttg gtacaggata ttcttctatt
     5281 agttgtttaa gagatatgcc aattgatata ttgaaactgg ataagtcttt tcttgatggt
     5341 attgaacatg atgagagaag tcgcaatata gcaaaatcaa tagtgtctct agcaaaatca
     5401 ctagatttag ttgtaattat agaaggtgtt gagagtaaag aacaagctga gttaatgaaa
     5461 caatttggat gtgatttagt tcaaggattt tattttgcaa gaccaatgcc agctaagaat
     5521 tttttagatt tactttgaaa taaaatttga tttttatata aagcactatt atgaatgctt
     5581 gattttaata aatcactgct aaataattag tgttttttta ttttatcaat gtattatcta
     5641 atataaggta aaaaataatt gtattttata aaaattatat taaaaataaa tttattttgc
     5701 taataaacat gtcattaaca aaagaatagt actataatgt atagatgata aaaactttaa
     5761 taaaaattta gtgtatagga gttgtttaag tatgatagat gtaagtattg ataaaaaact
     5821 taaggaaaga tggcctaatg ctaagctggg ttgtattcaa gcaaaagtag cagtaaataa
     5881 aagctcagaa aaattaatta atgaaataaa tgagttttgt gatactctaa ataaaaatct
     5941 aaaagttgaa gacattacaa aactagataa aattaaagat gccagaaatg catataaaga
     6001 acttggaaaa aatccaagta gatatagaac gtcttcagaa gccttggtta gaagaattat
     6061 tcaaggtaag ggtctttaca caataaacaa tatagtagaa ataaacaatt taatatcaat
     6121 aaaatcatta tatccagtag gtacatataa tgtaagtaaa ttacattcac cagtatgttt
     6181 tactgtagga gatgaaggag aacagtataa gggtattggg aaagaattaa taaatataga
     6241 aaatcttcct atattgtctg attcagtggg taaatttggg agtccaacta gtgattctga
     6301 aagagcaatg ataacagaag atgcgaatga aatattaatt tgtatatttt cttttagtga
     6361 agaatctgat attgaagaat attttggata tgctaaggaa ttacttaaag aatacgctga
     6421 tggaaaagat atagaaacta aaataattaa atagaatcca tataacaacg ttatgttaag
     6481 ctaaaattca atataaaaat aagttatgat aaagaaacta acacaaaatt agtttctttt
     6541 ttgaaagagt agtttagtgt tacaaaaata gatagatatc cccacgagta ttaaaagtat
     6601 ggtaatatat taatatagaa gggattgtat ttaagggatt ttgaaaggag tgatttataa
     6661 taactgtttt ttctaaaaga taaaatggtt ttatggaaat aactatatat ttaaaaatat
     6721 aaataataat acagtgattt gggtatataa aataagacat acatggtttt gtttaaaacc
     6781 aataaagtac ataggtaatt acaatgtaag gaaggattta attatgattg atggaaaaga
     6841 ggtaaaacaa gaaagtggac aaaaaaatct aaaatttaag atagctatag tagtaggtat
     6901 tttatttgta gcttatatag gaatggcaat cttttttaga aatcattttt actttggaac
     6961 gactattaat ggtgtaaggg cttcaggaaa aacagttgaa caagtaaatg atttgttaac
     7021 atctagtact aattcctata ctttaaactt agatgaaaga aacaataaga aagaacaaat
     7081 aaaagcaaaa gatattgatt taaagtttac accagatgat aaagttcaaa agataaaaga
     7141 tagtcagagt gctattggat ggattggtgg gatatttaag tctaaagagt ataacaatat
     7201 ggtaactctt tcatataata aagatttact agaaaaaaga tttaacgctc tatcttgcct
     7261 tgatagtaaa aatgttgtag agcctaagag tgcttatcct aagtatgata gtactaaaaa
     7321 tgcttatgtt atagtgccag aggtacttgg aaacaaagtg aaaaaagatg atttttataa
     7381 gttagtacaa aactcaatta attctggtaa tacttctatt tctttagatg aaagtaaagt
     7441 gtatgaagtg ccaaataaca caaaggattc agaaaagttg aaacaagcta ttaagacact
     7501 agataagtat gttggtgtag ttgttacata tgattttagt gaccgtaagg aaactttaga
     7561 tggttctgag attaataaat ggttaaaggt agactcagaa aagaattatg atataacttt
     7621 cgataatgat gctatggtag agtatacaag aggtttaagt aaaaaatata gtacttttgg
     7681 agattcaaga ccatttaaaa ctgcaacagg taaaaatatt acaatttcag gtggaattta
     7741 tggatggttg atagacaaaa agaaagaagc tgaagcatta gttgatgttg taaaagctgg
     7801 taaaaatgtt acaagagaac ctatttacat acaaaaagct gtatctcgta atagagatga
     7861 tattggaaat acatatgtag agattagtct ttctaaccaa catatgtggt tctttaaaaa
     7921 tggagaaatg cttgtatcaa cagacattgt aactggtaat ttagctagag gatttgctac
     7981 accatcaggt atatatcctc ttaattataa ggctagaaat gtttcattaa ctggtcaagg
     8041 ttacagttcc cctgtaagtt attggcttcc atttaatgga aatataggta ttcatgatgc
     8101 tacttggaga aattcttttg gtggaggaat atataagtct tcaggttcac atggatgtgt
     8161 aaatacacct ttttctaagg caaagaaaat atatgaaaat atagaaccag gtacaccaat
     8221 tattttatac tagtaaatgt gttactaaca gttaagcgaa gtcatcttag tttatttagg
     8281 gtggcttcct ttttatataa agtttattga agtttacata aagactattt aaaaggagaa
     8341 atacataatg aatgaaaaat taactaagat tttagagaaa gctaagaatg atgatgaatt
     8401 tagaaaagaa cttataaaat caagagaaca acgtgatgtt atggattcat tttgtaaggt
     8461 tgttacatct agaggttatg atataacagt aggggaactt ttttccatag gagaagaata
     8521 tacatcaaat ctacttaaaa gtgtgaatgg aggggcaaca tatcctattg aagattggag
     8581 tgattggtac gaggattttt ttataatgtt gtcgaatata tagagtaact aatgttatta
     8641 tctacttaag attaacacct taattttaaa aaaaactatt agagctaagt gtaaatttta
     8701 tcaatcttta aaaatattga tttatttcta gctatatata aaaaaattag attaaaaata
     8761 aggtgacaaa aatcgatata ccttgatgat ttataaaagt tagacaaaat agtgctagat
     8821 atttctaaaa attcaaaaaa aacaataaac ttcaagagct agaggttgaa aaataaaata
     8881 aaaaactttt atatgtaata aattaaattg aaattataaa aaaaataaaa aagaaatttt
     8941 aaatgtcgac atagcgttaa ttttaagaca aaataacgct attgacaaac tatatcgctt
     9001 taaattataa ttattgaaaa taatggtatt taaaaatcat actcatgcaa tagtctaaaa
     9061 gtaagtcaaa aaaaaatgta aatctaggca agtactattc taaaatatgt tttattaaga
     9121 aataaacgtt gaaaaatatt aattattata taaaaatgct gtttatactt taacaatgag
     9181 gtagtaatct aattagaata aaaaaatcta attggttata tacatagtaa aaaggtaaga
     9241 gaggtgattt ggatggcttt tgaaataata aaaagcattg ttgaggcaga gcagacagca
     9301 gacagtatca aagtaaaagc tgttactgat gcagagtcta tcagagctga tgctgtaaac
     9361 aaatgtgaaa gcatatttgc tgatgtaaaa aaacaagcaa agcttatgga agaaactctt
     9421 attgagaagg cagtcaccga cagtagagca gaggttgata aaatcttagc taatgctaaa
     9481 agtgaatgtc tgaaaattga aaaaactgct aaagaaagaa aaagtaaggc tattgaagcg
     9541 gttattggaa aggtagtgag ataatatggc aatagttaat atgaacaaaa tatctattgt
     9601 tggcttagaa gctcaaaaaa gccagatttt aaagctactt atgaaccgtg ggtttgttca
     9661 gattgatgat agtgcctttc ttactgagga ggaggaatta aaaaattatc ttgtaaaaga
     9721 tagtgaagaa tctgaagtta taatgctaga gcagaagatg tctcatgtaa accaagcaat
     9781 taatattgtt tcttcactag tgaaacaaaa aaaatcccta cttgcaccaa aaagagagtt
     9841 taacaaaatt gatagtgaaa aagaagagca agtttatgct gaagctcttg agttaaacaa
     9901 tttacacaag gagataggta caataaggtc taacataaac ttacttaaca acaataaaag
     9961 tatgttagaa ccgtgggtaa actttgatat tcctcttgaa aatatggaaa ctaagtatac
    10021 aaaaactata cttggaactg tacccataag tgcaaacatt gatggtttaa gagtaaaatt
    10081 agaagatgaa ataccagaaa gtgttattgg gattgtcaat tctgacaagt taatgaacta
    10141 tgtttattta atcactttaa aagaaacttt tgatgatgtt ttagaagttt taaaagaatt
    10201 taatttttca gtggtttcat tgccaaatga agaaggtaca ccgttacaag ctatcaagaa
    10261 atacaatgaa atgataatta gacaggaaaa cgtttctaaa gacaaaacag aggaaattaa
    10321 aagacatgca gagagtatac acatgcttga aaatctatat gatttttaca ctatagaaag
    10381 agaccaaaaa aagattatag agagacttgt caaaacaaaa acaacattct gtcttaatgg
    10441 ttggttacca agcaaaaggg cagatgagct aattaaagaa attacagaaa agtttgattg
    10501 ttgcgttcag actgaagaag gaagtaaaga agaaggcttc ccaattttgc ttgaaaacaa
    10561 taaactagta acaccttttg aaagtgtaac taacatgtac agctatccaa gtacaaaaga
    10621 tattgaccca aatacaattt taacattctt ttttgttgta ttctttggaa tgatgctaag
    10681 tgacgctgca tatgggttaa taattgcact agtctgtgga tttgttgtat ataaattaaa
    10741 gatacaaaaa ggtgaaggaa atttaattaa acttattggt atctgtggag tttcaactac
    10801 tgtatggggg cttatattcg ggggtgtttt gggggattta attcctataa aagcattaat
    10861 taatccttta gaggatgtta tgacacttat gggaatgtcg ttactgttcg gtattatcca
    10921 tatatatgta ggtttgggaa taaaagcata tacattaata agaagtggaa aggtaataga
    10981 tgcaatcttt gacataggtt tttggtattt gtgtataaca ggtgtatgtc tacttataat
    11041 accttttgtt gcaggggaca taggtgtatt ttcagaagta ggaaaatatt tagcaattat
    11101 aggtgctata ggtcttgtac ttactcaagg aagaagcttt aaaggtattc ctgttaagct
    11161 ttttaaagga ttttcaagtc tctatggcat aacaagttat tttgctgata tattatctta
    11221 tacaagaatt atggcacttt gtttaacaac aggagttata gcacaagtta tcaacctttt
    11281 aggagctata gctggtccga tacttgcagt tgtaatcggt gttgtaggac acacaataaa
    11341 ccttcttata aatgcactag gtgcatatgt tcatacaagt aggttacagt atgtagaatt
    11401 tttcaataag ttttatgaag gcggaggagt tccttttgtt ccgtttaagt ataaaacaaa
    11461 atatacaagc attaataaaa aggagatgta aatatggaat ttttaaacgc gttaggaaat
    11521 ggtcaatttt tggcaatatc aggagctgct atagcagcat tatttgcagg tatgggttct
    11581 gctaaaggta cttcaatagc aggtcaagcc gcagcaggtg ttgtaacaga agaccctagt
    11641 aaattcggtc aacttctagt tttacaactt cttcctggta cacaaggttt gtatggattt
    11701 atcatagctt tccttatttt atcaaaagca gggattattg gtggagatgc aataccaaca
    11761 tcagctcaag gtttacaact tcttatggca ggacttccaa ttggtttagt tggtttagta
    11821 tcaggtatag cacaaggtaa agcagcagca gcaggggttg gaatagttgc aaaaagacct
    11881 gaagaacttg gtaaagctat aacatttgca gcaatagttg aaacatatgc tcttttagga
    11941 ctacttgttt ctttcttagc ttacaatgga attgcaattg gttaattata gattataatt
    12001 cataagtaaa aaaaatgaaa aggaggaagc actcctatgg gtaatgaaca aaaaatgatt
    12061 gacagaatta tagctgatgc caaacaagaa gcacaagaaa tattggataa ggctaaaagt
    12121 gaggcagatt taaaagtaaa ttcagctaat gaaaaagctg aaaaggaaat ggcttcctat
    12181 acaaagcttg cagaggcaga agcagaaaaa gcagcttcta aggaaatatc aggagcttat
    12241 atggaggcta aaaaacaaat attatcaaaa aaacaagaga ttttagaaga ggtaatttta
    12301 gaagctaaaa acaaacttct aaatcttaaa gataatgaat atgaagagat tatactaaac
    12361 atgattgaaa aatcaaattg tacagatgat tcagagatag tattatctaa aaaagataaa
    12421 aaaacattaa aagatgtgct atcaaaaaaa ggcattaaag tgtctgatga aactagagat
    12481 attactggag gtttcatagt taaaaaaggt gacattgagt acaattattc atttgaagcc
    12541 ataattgcag tagagcatga atatattgaa caaattgcag cagaaatttt gtttaattaa
    12601 ggaggggtta aaaaatggca gaagaaaaaa cttatcccta tgccgttgca cgaataagag
    12661 tgcttgaaaa acagcttctt aacagacaaa tgtttattca aatggcagaa gccaaaagcc
    12721 ctgaagactc tttaagaatt atagctgagg caggttatgc tgatacatca aataataata
    12781 tacataattt tgagaatatt ttgactcaag aattatcaaa aacatatgaa attcttaaaa
    12841 gtctagctcc tgaagaaaaa tttgttgatg tgtttcttta taaaaatgac tatcacaatt
    12901 taaaagtgct gattaaagaa gaaatttctg gtgtagatgg tgagaaatat ttaattgatg
    12961 gaggtacaat tcctcttatt aagcttagag aatctttagc aaatcgtagt tttagtgatt
    13021 tacctaaggt aatgtcatca gctatattag aggcatttga tgtttatagt aagacacaaa
    13081 atggccagat ggttgatatt gttctagata aagcgacttt tactagtatg aaagaaactg
    13141 ctaaagaaag tcaaaacaaa tttgtaatag attatgttat gaaagtttgt gatttaacaa
    13201 atctaaagag ttttataaga gtcaaaaata tgaagaaaga ttttgatatg tttatgaatg
    13261 tgtttgtttc aggtggctca cttgataagg aaaaattttt agaagctttt tcctcagata
    13321 ctccagcatc atgttttaaa tctacttctt actctgatgt ttgtaaaaat ggcatggata
    13381 gtggttttac tgtctttgaa aaactttgtg atgactatct tatggaatat gttagagggg
    13441 caaaatttaa gccacttaca ttagaaccac taattgcata tttatatgct aaagaatcag
    13501 aaataaaaac aattagaatt attttgacta gtaagcttaa taatatagac gcagatacta
    13561 taaaagaaag gctaagggat gcttatgtat aaggtaggag tagttggaga taaagatagc
    13621 atcatgggat ttttagctct tggaatagat atcttcccag cctatgatag tgacgaaatt
    13681 aaaaaaagta tacataagtt ggttgaagat gaatatgcga taatttatat tacagaacag
    13741 gcatcattgc ttgcaaaaga atcaatagca aaatacaaag attaccaact tcctgctatt
    13801 atagttattc caggtattgg aggaagtatg ggactaggta tgaatgaagt aagagaatct
    13861 agtaaacgtg ctataggtgc agatatatta tttaaagaat agatgaaagt tgaataaaag
    13921 acaatctcaa attttattgg tattaaagat atctactaat aaaatatagg agggaatatt
    13981 taaattttga taaagtatat gattgcaggt gagagaatat gaaaacaggc acaattgtaa
    14041 aggtgtcagg accgcttgtt gtagcggagg gcatgagaga tgcgaatatg tttgacgtcg
    14101 taagagtttc agataaacat cttataggcg agattataga aatgcatgga gataaagctt
    14161 ctatacaggt ttatgaggag acttctggtc taggaccagg ggaagaagta gtttctcttg
    14221 gaatgcctat gagtgttgaa cttggaccag gtcttatttc aactatttat gatggtattc
    14281 aacgtccact tgaaaaaatg tatgatattt caggtactaa tataactaaa ggggttgaag
    14341 tatcttcact tgatagaaca attaagtggg aatttaaacc taagaaatct gttggtgata
    14401 aggttgtagc aggagatatc attggtggag ttcaagaaac agcagtagta gaatgtaaaa
    14461 ttatggttcc ttatggagtt aagggaacta taaaagaaat atattctggt gaatttactg
    14521 ttgaagatac agtttgtgtt attacagatg aaaaaggtaa tgatatacct gtaactatga
    14581 tgcaaaaatg gccagttaga aaagaaagac catatagaga aaagaaaaca ccagattcac
    14641 ttcttgttac aggtcaaaga gttatagata catttttccc aattacaaaa ggtggggtag
    14701 cagctatacc agggcctttt ggaagtggaa aaactgttac acagcatcag cttgctaaat
    14761 gggcagatgc agatatagtt gtatatatag gctgtggcga gcgtggaaat gaaatgacag
    14821 atgttcttct tgaatttcct gaattaaaag acccaagaac aggcgagtca cttatgcaaa
    14881 gaactgtgct tatagcaaat acatcagata tgccagttgc tgcacgtgaa gcttctatat
    14941 acactggtat tacaatagct gaatatttta gagatatggg atatagtgtt gcacttatgg
    15001 cagactctac atcaagatgg gctgaggctc ttagagagat gagtggtcgt ctagaggaga
    15061 tgcctggtga agaaggttat cctgcatact taggttcacg tcttgctcaa ttctatgaga
    15121 gagcaggaaa ggtaaattgt ctaggtatgg atgaaagaga aggaacactt acagcaattg
    15181 gtgcagtttc tcctcctggt ggtgatacat cagaacctgt cagccaagca acacttcgta
    15241 tagtaaaagt attctggggt cttgatgcat ctttagcata taaacgtcat ttcccagcaa
    15301 ttaactggtt gactagttat tcactctatc aggaaaaagt tgatgtatgg gcagataaaa
    15361 atgtaaatga taatttctca gctcaaagag ctcaagctat gaaactttta caagttgaat
    15421 ctgaacttca agaaatagtt caattggttg gtgttgactc actttcagat ggagatagat
    15481 tgatactaga ggttactcgt tctataagag aggacttcct tcatcaaaac tctttccatg
    15541 aagttgatac ttatacatca cttcataaac aatatagaat gatgggactt atattaaaat
    15601 tctataagtc agcacaagat gctatcaagc aaaatgttac tataaacgat attatcaagc
    15661 tttcagttct tgaaaagatt ggtcgtgcta agtatgtaga ggaaggcgac atagatgcag
    15721 cttacgattc aattgaagat gaaatagaca acgagcttgc agaccttatt aaaaagaggg
    15781 gggctgaaga actatgataa aggaatataa gtcaatacaa gaggtggccg gtcctcttat
    15841 gctaataaac ggcgtagaag gtgtaaaatt tgatgaactt ggagaaattg aactttcaaa
    15901 tggagagatt cgccgttgta aagttctaga ggtaaacgga gatactgcac ttgttcagct
    15961 tttcgaaagc tcaacaggta taaaccttgc tgaaagtaaa gttcgtttct taggaaagag
    16021 tcttgacttt ggagtttcac cagatatatt aggtcgtgtt tttagtggaa tgggtagacc
    16081 tattgatgga ggtccagaaa ttataccaga taaaagactt gatataaatg gagctccaat
    16141 aaatccagca gcacgtgact atccggctga atttatacaa actggagttt ctgccataga
    16201 tggacttaat acactggtta gagggcaaaa acttcctata ttctcagggt ctggtttgcc
    16261 acatgccaat cttgcagttc agattgcaag acaggcaaaa gtacgtggaa ctgattctaa
    16321 gttcgccgtt gtatttgctg cagttggtat aacttttgaa gatgctgaat tttttataag
    16381 tgatttcaaa gcaactggtg caatcgaccg ttctgtagtg tttgtaaacc ttgcaaatga
    16441 cccagctgta gagcgtgtat ctacacctag aatggcactt acagcagcag aataccttgc
    16501 ttttgagcaa gatatgcatg tacttgttat aataacagat attacaaact atgcagaggc
    16561 attgcgtgaa gtttcagcag ctaaaaaaga agttccagga cgtcgtggat atccaggata
    16621 tctttatact gaccttgcta ctatgtatga aagagcagga aaaatgaaag ggcatgaagg
    16681 gtctataact atgattccaa tacttacaat gcctgaggat gataaaacac atccaattcc
    16741 tgaccttaca ggatacatta cagaaggaca aattatactt agccgtgaac tttataaaaa
    16801 agatatacag cctcctatag atgttttacc atcactttct cgtctaaaag ataaaggtat
    16861 tggtaagggt aagactcgtg aagaccatgc agatacaatg aaccagcttt ttgcagctta
    16921 ttcaagaggt aaggatgcaa aagagcttat ggctatactt ggtgaatctg cactttctga
    16981 aattgattta atgtatgcta agtttgcgga tgaatttgag aaagaatatg tttcacaagg
    17041 atttagaact gatagaacta ttgagcagac attagaaatc ggatggaagc ttcttagtat
    17101 gttaccaaaa agtgaactta aacgtattcg tgatgaatat tttgaaaaat atatgcctaa
    17161 ggagtgatat ctgtggctag attaaatata aatccaacac gtatggaaat gactagactt
    17221 aagaaactcc ttaaaactgc tacaagaggt cataagcttc ttaaagataa acttgatgaa
    17281 cttatgaaac aatttcttga gattgtaaga gaaaataagc gattacgtga agaagcagaa
    17341 aatgctcttg atgctgctta taaaaatttt ataatcgcaa gagcagttat gagtcaggag
    17401 tatctgggtt cagcacttat gatgccaaag caatctgttt cagtagatgt ttctactaga
    17461 aatataatga gtgttgatgt tcctgtgttt gactttaaaa ctgaaaacaa tcaaagtgat
    17521 atttatcctt atggtcttgc ttttacatca ggtgaattag attctgctat ggaagctttc
    17581 tcagctgcta tgcaaccact tttaagactt gcagaaagtg aaaaaagtgc acagcttctt
    17641 gcacaagaga tagaaaagac acgtagacgt gttaatgctc ttgaaaatgt aatgatacca
    17701 aattacattg agactattaa gtatatagct atgaagcttg aagaaaatga gagagcaagt
    17761 actactagac ttatgaaagt taaggatatg gtgcttaaaa aagcacttga agaaaagaaa
    17821 aaaaatgatt tggttgtata attaaatact tataaaaata agtctaacat tctaatttat
    17881 agaggttagg cttattttta tgtttaaatt aaaagtgtaa atagtataaa aatcaataca
    17941 ttgtttaaaa acagactgta tttaactaaa aataatatat ttaacaaaaa tttctaaaaa
    18001 ttaacgaact gttaatttac acttaacttt atattaacaa attaggtgta ttatataaac
    18061 ataagcaaaa acaataaaaa acaaataaaa aaagaaaaaa acacaaaggg ggaagatatg
    18121 aaagaattta tatttacttg tctgtgcatt gtagtgatta catttatgac aagttgcata
    18181 tcaacaacac cacaaactac tcaaggaaaa ggaaataata aacttacaat atatgcagca
    18241 ctagaggaag agcagatagc ttactatatg gaaggtttta gagaagagta tcccaatata
    18301 gatgtagaga tagttatgga ttctcatggt gtaatagctt caaaattatt agcagaaaaa
    18361 gataatccac aagctgatgt tatatgggga ttatcagcaa tgaacatgat agaactaaaa
    18421 gaagatggtg cacttgaagc atataaacct aaacactatg ataaagttga taaaaaattc
    18481 aaagatactg aagatgatgt atcttgggta ggaatgagtg tcccggaaac agcaatagta
    18541 gttaattata aggaacttaa gaaactaggt atagatattc caaaaagtta tgaagattta
    18601 ataaaaccag aatataaagg acttataaca atgccaaatc cagcatcatc tggaacaggg
    18661 tatcttacag tatcaggcct tattcaaatg atgggtgcaa aagatgctta caattacatg
    18721 gataaattac ataaaaatat agctacatat acacactcag gttcaaaacc tgcgaaacta
    18781 gctggttctg gagagtatcc aataggtatt acacttggat atagagctac acaacaatta
    18841 tccagtggag aacctgtaga agttgtattt ccaaaggaag gttcaggttg ggacttagaa
    18901 gcaaatgcct tagttaaaaa agataatata aaaaaagaag caaagttatt tttagattgg
    18961 gcaataagtg attcagctat ggatagatat tcacatgaag tagcagttac ttccataaag
    19021 acagataatc cagttccaaa aggttactct aaacaaccat ttgaacagct tataaaagaa
    19081 gttgatttaa gttctgcggc taaaaacaga agtacagtac ttaaaacttg ggaatctaaa
    19141 tatggttcaa aatctgaaag taagtaaagt ttaaattaat aatttagatg aaagaatttt
    19201 agaaaaaaag gtaggatata gaatttaaga taaaaatata actatataag gagagataag
    19261 atatgagtta tttaaaaata aagaatgtgt ttaaaaatta tgaccaaaaa agagttttaa
    19321 ataatattag tttggatatt gaagaagggg aatttctatg tttacttggg cctagtggat
    19381 gtggtaaaac tacattactt agaataatag caggtcttga agatgtaaat agtggagata
    19441 taattcttca ggataaagat attacaaatt tagaaccatc aaagagaggt tttggtatag
    19501 tatttcaatc atatgcatta tttccgaata tgactgctta taacaatata gcttttccac
    19561 taaaagagag aaaaatttca aaagaaaaaa tagataataa agttaaggaa gtacttgaaa
    19621 tagttgggtt gaccaatgaa gctcataaat atcctaaagc attatcaggt ggacaacaac
    19681 agaggattgc aatagcaaga gcattagcac ttgagccgaa gtttttactt ttagatgaac
    19741 caatgtctgc attagatgca aaggttagac acaagcttag aatggacatt aaaaggctac
    19801 aaaaagaact taatataacg acaataatgg taacacatga ccaagaagaa gctataacta
    19861 tggcagacaa aatagctatt ctaaatggag gagatataat gcaaatagga actccagagg
    19921 aaatatacca aaatcctcaa aacctattta cagctcaatt tataggagat acaaactgtt
    19981 ttgataatgg agattctata ttaactgtaa gaccagaata tgttcaaata gagaaatcga
    20041 caaaagaaaa ttaccaaggt ataatatcaa atatagagtt tagagggaat ttattaagag
    20101 ttgaaataaa agataaacta aatgaaaatt tcataataag tgatgtttct ataaaagagt
    20161 gggttaattt aaatttagta gaaggtgacc ttgtaaagat aagtatagac gaaaaatact
    20221 atttaaagta tccaaaagtt aaaggagcat aaaggtatga ataataatgc tataggttat
    20281 aaaagtataa gtcttaaatc aaaaatgaat ttagatataa aaaaatgtat gcttacagta
    20341 ttagttatgt ctttagtaat atttttattg gcacctataa tatatctatt tgtacaggct
    20401 tttttagata aagatggagt ctttgtagga ttacaaaact ttcaagaata cttggcttct
    20461 gaaactctat taaattctct aaaaaataca atatttgttt cagttatatc aactgtaata
    20521 tcactagcac tagcactagt atatgcatat gcattaacta gaacaaatct taaatttaaa
    20581 ggttttttta aatcattagc aatgtttcct atgtttgctc caacaatgat gcatgcaata
    20641 ggtctagtat atttatttgg gaatcaagga ttggtaacta atttacttgg aatacatgtt
    20701 ccaatttacg gagcagtagg aataatactg gcacagatta tatatgtatt cccacaatca
    20761 tttcaaatac tttatatatc tctaaattca actgattata gactatatga agctagtaat
    20821 actatgggga taagcaagat aagagaattt ataagcataa caattccaag tataaaatac
    20881 tctttaataa gttctgcatt cgtatcgttt acattatgct ttacagattt tggagctcca
    20941 aaggtaatag gaggagagtt taatgtatta tcaatagatg tttataagca aattataggg
    21001 caacagaata tgccaatggg agcaactgta tcaatattac ttttaatacc tgcaataata
    21061 tcgtttatag taactaaaaa aattgaaaaa aatcaaaact catatataac ttcaaagtca
    21121 attccatata aggttaaaac taataagtta agagatagta ttttaggagg aattgtagga
    21181 attattgcat ttggtataat atctgtaatg ttaactgtaa tcttatcatc attaatatca
    21241 gtttggccat atgatttaag gcttacactg gaacactttt ctatgaaaaa tagtattgat
    21301 ggaattaaac catttataaa ttcaataaaa atgtcattat tgacagccat tctagggacg
    21361 agctttgttt tcttatttgc atatttaaat gaaaaaacag aaaaagcccc ctatttaaaa
    21421 tcatttgggt attttttaag tacattgcct atggcattgc caggattagt tttaggtata
    21481 gcttatgtat tattctttaa taaattggag tttgatttta tggatacaat ataccttaaa
    21541 aatctgttta atggattata tggaacattg cttattatgg ttatatgtaa tatagttcat
    21601 ttcttttcag tagcatttat aacagctact actgctatta agaaagtaga taaagaattg
    21661 gatatggtag ctaaatcaat gggaataaac agcgcatcaa ttcttaagaa tgtaactata
    21721 ccactttgtt tgccagcagt tttagagaac tttatgtact ttttcctaaa ctctatggtt
    21781 acaatatcag cactagtttt tatatatact gcaagttcaa aagtagctgc aatatcaatt
    21841 gtacaactag atgataaggg gagtactgca caggcagcag cactagctgt gttaatatta
    21901 atcacaaata tattagtgaa agcaatacat gaatttataa agaatcgttt agaaaaaaga
    21961 acaaacttta attaaagaaa ttattctaca aaattataaa tttaaaaagt ctattctcac
    22021 aatttattat ttacagaata gactttttaa atttattatt aatattattt attaattttc
    22081 cttttgttat catacatttg agaatctgca taattatact tataaaataa agaaatattt
    22141 attaaaattt tctgtaaaat ttttagtttt actggaagat tagattcaga atattatcaa
    22201 gctaagtttg actaattatt aagtttcgca tcaaaacaat gttttaatag tgtttacagt
    22261 tgaagttttt tataaaaagt ttagttcccg tttaaaattt atatttattt tgatattttc
    22321 ttaatttata atatattata ttaatacata gttattagaa ataagacaca attaaataat
    22381 tatataaaat tgggaggtta aaatgggaag ggccaaatat tatgatatat atatagattt
    22441 aaaaaataga atagaaaaca aggaatattt ataccaagat ttattaccat cagaatacac
    22501 attaatagaa gagtataatt gttctagaaa tacaattaga agagctatac aggaattagc
    22561 aaaccaagga tatgttcaaa gtaagcatgg aaaaggagta tttataattt acaaggctaa
    22621 caagcaatca gagtttttat taggaggaac agaatcattt aaagaatctg ctattagaaa
    22681 caagaaagaa tataaaacga aagtagttca ttttgaggaa atggttatag atgataagaa
    22741 aagtcaaata actaactttg aagttgggac agaagtgtat tatatacaaa gagtaagaat
    22801 tctagaaaat aaaccatcta ttatagatca taattatttt atgaaagata tagtaaaaga
    22861 tattaatgaa gaaatagcat ctaattctat atatgaatat atggaaagtg aattaaatga
    22921 gactatagta acaacaaaaa gaactatgac agttgaaaaa gcaactaaac tagataaaaa
    22981 gtatttagaa ttaggagatt ataattgtgt tgcagttgtt agcaataata cttataatgc
    23041 ccaaggtata atgtttgaat atacgcagtc tagacacata cctgatggat tcatattttt
    23101 tcatcaatct caaagaatta ataatataaa atagagtaca atttgtactc tattttatat
    23161 tattaattct ttgagagtta tactcataaa ctttagcagc taagtatatg aatgtactag
    23221 ctgtccaggt gaaagattta tctctaagac cctctcctgt aatagcgttg aaattttcag
    23281 caaagccgtt tttatcaact aattcacaat atcttttggc aatatctatt gcaagttcat
    23341 tttcaccaca ttcttctaaa gcttcaacaa ataatagtgt agtaggagcc caaataggcc
    23401 ctctccaata agcatcatct tgatattcat cactatctat agcttctgtt gcgattcccc
    23461 atttagttaa atatctttcg ctagtgacta aatctatcat tttgtctcta atatatttag
    23521 gaagtctatt tcctaaaact aaagaaacaa gaggaagtaa agcgttgtta gaaagtattt
    23581 caccagttac agtttcgcga gctacaggta aatcatcaac tataaaataa tttaagaata
    23641 actttgtaag ttcatctgct ttattagacc aatactcttt ttcactattt ctgtttagtt
    23701 tttcagctac ttttgatagc atgtccatag catttattat aaatgctgtt aaatcaggag
    23761 tatcaacaac catagctcct ttaaatattg tactattatc ctgtccagaa tcatttccat
    23821 ggtgatattc aaaaatacca tccatatttg aatctttaaa ctttacataa aacaatactt
    23881 gtttttctat gtaattataa attttttcta atgtttcttt agtaaagtta atttttttca
    23941 tcatcttact aaaaaataat ccttgaatag gtggttttgt aaaattccat ctaatagtag
    24001 aatcgcttaa ggacccagga atttgaccat attcatcttg gtagtcgaaa agtactgcca
    24061 tttggtcaaa agctaattta tcatttacac cagctaaagc taatgcgtta aaacagtgat
    24121 cccagctcca tgcacctaag aatgttgagt ttgaagcaag tatagtatat ctctttaggt
    24181 atccttgagg tttgacaaaa gaagaccaat ttatataact cgcttttaaa agtgagtttt
    24241 tatatttttc atctacttta ggttgagcta gataatattc atcaaataat ttttttgtgc
    24301 tatttagtga agtttcaaag ttatattcct tgtaatctgg aactttcata tgagtaggaa
    24361 tgtcttctat aacacatata aattcattat cactattact tttaacatct attattgaag
    24421 tattattagc tttatttgta gaagcacagt catctataaa tatattttgt gataagccaa
    24481 ccttaccatt aacagagaat actaaaaact tagttaaatt tttgtagcta tttataacac
    24541 aatattctga acctttttta cccataaggt agttatattc aaaattgtat atgggaagtg
    24601 tatctagttt aagacctaca ttttttccct taccatagaa tacgatttta gaatctcctt
    24661 caaaacatat agatatacta ccattgttga atttaattaa tatactaaaa tagttagcct
    24721 caaattcata atctacaggc atgttattta ctgtaggtat aatccttagt acatccatat
    24781 ttttctttga ttttcctctt aatgatttta atgtaaatcc aagttcatct gaataagaaa
    24841 tagacatata agatccaaag taactaaacg gaatttcttt tatattcatt tggtatagtc
    24901 ctttcatgat ttattttata gatttactct gcttgtttat acaagtaagt atatatttaa
    24961 cttaccaaat aataaaataa ttatcaagag ttaatttatc aaaaaaataa ataagaaaat
    25021 gttttcaaaa aactattgac taaaataata taaaatatta caataaagtt gttcaaacaa
    25081 gttacttgtt taaacaactt attacttata ataaaaaaga gaaaggataa gtagatatga
    25141 ggaagaataa gatactaaat tcaaaagaaa gtatttccaa aattattgag tatgttgggg
    25201 gaaaagaaaa tatacaaagt gcaacacact gtgtaacaag attacgttta atattaaaag
    25261 atactagcaa agcaaatatt agtaaactag aagacattga tatagtaaag gggtgtttca
    25321 atgcaggcgg acagtttcaa atagtaatag gaactggagt agataaagta tataaagatt
    25381 taatagacca aacaggagca gaagaagtat ccaaagaaga aattaaacaa caagtcaatg
    25441 aaaagtcaaa taaatttcaa aagtttataa gaatccttgc agatatattc attcctatat
    25501 taccagctat agttgcatca gggttactta tgggtgttaa taatatgata gctaatccag
    25561 ggatttttta tgagaagtct gttatagaag taaacacaga tatagctggg atttcaggta
    25621 ttataaattt aatagcaaac acatcattta catttttacc agcattaata ggttggtcag
    25681 ctgcgaagaa atttggagga aatcctttat taggtgtagt tttaggtctt gtattagttc
    25741 acccagcttt gatgtctgca tatgattttg cagcaaatcc atcagcagca ccaacatggg
    25801 atatatttgg tatgaaggtt gctcaagttg gataccaagg tcaagtaata ccagttttaa
    25861 tagctacata tattttagct aaacttgaat tattcttaaa gaaaactgtt ccagatgcag
    25921 ttcaactagt attagtttca ccaatagctt tattaattac aggtatgtta acttttgtag
    25981 ttataggacc tataactatg acaggtgcaa atatgataac taatggagta gtatatttat
    26041 ttgaagtagc accagttttc gcaggagcac tatattcatt tatttcacca ccattagtaa
    26101 taacaggaat gcatcatttg tttttaggag taaacttaca aatggcagga actttaggat
    26161 atgtaacatt gtggccaata tcagagactg ttactttagc tcaaggtgct gccacattgg
    26221 caatgttttt catacttaaa aataataaga atttaagggg tgtatctatt acatctacta
    26281 tatcagcatg gctaggaata acagaaccag ctatatatgg tataaactta agatttagat
    26341 atccatttat agcagttatg gtagcaagtg caataggagg agcatttata tcatatcaca
    26401 atgttaaagc tacagctgtt ggggttggcg gagtattttc attcctttca gtgatgcctc
    26461 aatattgggg agtatatttt acgggaatgg caataacatt tgtaataaca ataggattaa
    26521 catacttatt ctataagagt ggtaaattta aaacaaatga caatatataa atataattcc
    26581 cttggtttta tatcaaggga tgttaatatg cattggatag ataggagaca atatgttaga
    26641 ttttaaaaag agtatagtgt atcaaatata tttaaagtcg tttaatgata caacaaataa
    26701 tggtttagga gatttaaatg gaataacgga aaaattagat tatttagaat ttttaggtgt
    26761 tgattatgtg tggattactc cattttttgt atcaccacaa aatgataatg gatatgatgt
    26821 agctgattat tataatatag accctatata tggaactatg gatgatttag aaaatttaat
    26881 aaaagaagct aaaaaaagaa atataggtat catgcttgac atggtgttta atcatacgtc
    26941 tatagagaat gagtggttca aaaaagcact taaaggagat gaatactaca aagattttta
    27001 tatatttaaa aatcctaaag aagataaaag tgctccaaca aattgggaat caaaatttgg
    27061 aggcaatgct tgggaatttg tagaagaatt taatcaatat tatttacatt tatttgataa
    27121 aactcaagca gatttaaact gggaaaatcc taatgtaaga aaagaattaa aaaatatatt
    27181 aaagttttgg atagataaag gtataaaagg atttagattt gatgtcgtaa atttaatatc
    27241 taaaccagag aagtatgaag atgatttaca agatgatggt agacgttttt acacagatgg
    27301 taaaaaagta catcaatact taaaagagat gtgtgaagaa agtggaatat tagaaaatga
    27361 tatgttaact gtaggagaaa tgtcttctac gactatagaa aactgtgtaa aatattcaaa
    27421 tccagatgag aaagaattgt ctatgtgttt taattttcat catttaaaag ttgattataa
    27481 aaatcaaaat aaatggatgt tgcaagattg tgattttatt aagttaaaaa aaatacttaa
    27541 tgagtggcaa ataggaatgc aaaaaggtaa tggatggaat gctttatttt ggtgtaacca
    27601 tgaccaacca cgcataatat ctagatttgg agatgataaa aagtattata aagaatcggc
    27661 taaaatgtta gctactatga tttatctctt aagaggaaca ccatatatat atcaaggtga
    27721 agaaataggt atgactaatg catgttttac taatataaaa caatatgtag atgttgagag
    27781 tttaaattat tttgatatat taaaatctaa aggaatgaaa gatggtgaga tatacaatat
    27841 attacaagaa aggtctcgtg ataattcaag aacacctatg caatggaata atagtaagaa
    27901 tgcaggtttt agcgaatcaa aatcatggat agaggttata aataattata gaaatataaa
    27961 tgtagaaaat agtttaaaag ataaggattc tattttttat tattataaga agttaatagc
    28021 attaagaaaa aagtatgatg tagtagccta tggggatttt agaccattat tagaagaaca
    28081 tgattctata tttgcatata agagatgtta cgaaaaagaa tctttagtag tgttaaataa
    28141 cttttatgat aaagaaattg atgttgtttt agagaatgaa gagcttgaaa aatacaagtg
    28201 tataatatct aattatgggg acagaaaaat tgtttcaaca attactttaa gaccgtatga
    28261 gtgtatagct ttatttaaaa atgaaaaata atctaaaatt aaaatcatga aaaatttatg
    28321 tatacttttt agataaattt tatttttgaa gtcataattt aatatttatt agtaaggctg
    28381 tgattgtaaa aatcatagcc ttattttaat attttttcca catatacaaa ttattgttta
    28441 tattaaggaa atttaattta tattaaatgt atagacattt tctttgtttg tatataaaat
    28501 tatcttatta tataaaaaat ttaattaatg aggagtgaat taaatgaaag agccaattta
    28561 taaagttata gaaaatcatg ttagagagtt aataaattca gacagcttga aagaagggga
    28621 tttaatccct tctgaaaaac agttgagtga agagtttaac gtaacgagga tgactgtaag
    28681 gtctgcactt aataacctag ttaaagaagg atatataact agacaaagag gagtaggtag
    28741 tatagttctt gcaaataata tatacgataa tatatcatct gtaagtgggt ttactaaaga
    28801 gatggaaagc aaagggtata aagtatctaa tatattggta tctcttgaaa tagttcaagc
    28861 agatgaagaa ctatcaggta aattaaatat aagtttagaa gaaaatgttt gggaaatcaa
    28921 aagggtaagg ctagcaaatg atgcaagagt ttcatatatg attacttata tgccagttaa
    28981 gttatttcca aatttaaata agactcattg tgaaaattct ctttataatt ttgttgaaga
    29041 agtgtgtgca tataagatag ccatgtcaga gagagaagta caggcagtaa tatcgaataa
    29101 agagtgtatg gataatctaa aactagaaga accagagcca cttttatata taagccaaat
    29161 ctgtaagtta caaaatagtg agatttttga atactcacac acatatcact atggatatac
    29221 attaactttg aatgctgttg tcgaataaaa tttaaataaa atgaaaaagt tttcttgaaa
    29281 tgtatataca tttggtatat aataatatca agaattaaat gtatatacat ttaaaaataa
    29341 gatatataca ttaagaaaag attaatagaa aagcatactt taaatgtata gtttaaaaaa
    29401 cttatgactt aaaaagtatt taatgaattt aatttggagg ggaaaaaatg ataaaaataa
    29461 tgttagcttg ttcagcagga atgtcaacta gtttattggt tacaaaaatg gaggatgcag
    29521 caaaggaaaa cggtatagaa gcaaaaatat gggcaatatc agaagtgaac ttaaaaaatg
    29581 aaatagaaaa ttgtgatgtc ttacttttag gacctcaagt tagatatgta ttgggaaaag
    29641 caactgaaat ggcaaaacca tataatattc cagtagaagt tataaatatg atggattatg
    29701 gaagatgtaa tggaaaagct gtgttagaca gagctgtaga gttgaatagt tcaaaataaa
    29761 gtcgtactgg aggatgtaaa atggaaaaat tcatgtcatt tatggataaa tatatagtgc
    29821 ctgtagctgc taaaatagga gctcaaaggc acttggtagc agtaagggat gcatttatag
    29881 taatgatacc tataactatg gtaggtgcat taggaacatt gataaataac ttaccattag
    29941 aagcatacaa aaatttgatg gcaagtatat ttggagaaaa ctggactacg tttggaggag
    30001 acctttggtg gggagcaata ggtacaatgg cagtcttctt agtaataggt gttgcctatt
    30061 ttctagcaaa atcttatgaa agtgatggat tacaagctgg gcttatagca ttatctatct
    30121 tttttataat ggccccacaa attggtaaaa tagttcctga gggaggaact acagtagttg
    30181 aaggatgggg aatgatacaa caaacttact taggtacagc agccttattc tcttctatat
    30241 taataggatt gctatcaact gagatatttg taagattatc taaagtaaag aaattaacta
    30301 taaaaatgcc agatggagtt ccaccagcag tttcaagatc atttgcaaag ttaataccag
    30361 gaatgttaac tataatgata tttactgtaa taggaatatt tataaaaatg ctttcaaatg
    30421 gaagtttctt aacagatatt ttaaatactt atttaggagc accactatca aatgtagctg
    30481 atagcctagg ttctacaatg cttattgcat ttataattca tatactttgg actgttggac
    30541 ttcatggtgc aaatatagca cttcctttta cagaaactat acttatgaaa ttaggtggag
    30601 aaaatgctgc cttggctcaa gcaggagcaa cagaaggata ccatgtactt gcaggtgcat
    30661 tctttgatgc atttgtatat ttaggcggtt ctggaatggt attgggatta attgtagctt
    30721 tattaatagc tggaagaaga cgtaaagaaa tgatagtatt aggtggacca cctgcaatat
    30781 ttaacatagg agaaccattg atattcggac ttccaatagt tttaaatcct atatttatga
    30841 ttccatttgt acttgcacca gtaatatgta gtgctgtatc atacttagca atagattttg
    30901 ggttagtagc accagtaatt ttacctaaaa taccttgggt aacacctcct atattaggtg
    30961 gagcaatggc tacaggtgac tggactggtg gagctttagc actatttaat ttaatattat
    31021 caatattaat atatattcca tttgttatag cgtctgaaaa aatggaggct aataaattga
    31081 aaattaacaa ctaggtagtt ttatttcggt aaataaatgt atagggtttt gtatagtgta
    31141 ttaaattata ggtaaggatg gtataatgag atgaaaaagg gactaaaaat agttacaatc
    31201 ggaggaggtt caagttatac tcctgagctt gtagagggtt ttataaatag atatgaagag
    31261 ctacctgtaa aggaattatg gcttgtagat atagaagatg gaaaagaaaa actagagata
    31321 gttgggaatc tagctaaaag gatggtaaaa aaagctggaa tagatatgca aataaatctt
    31381 accttagata gaagagaagc actaaaagat gcagattttg tgacaacaca acttagagta
    31441 ggtcttttag atgcgagaat aaaagatgaa actattcctt tatctcatgg agttatggga
    31501 caggaaacta atggtgctgg aggtttattt aaagcccttc gcacaatacc agttatattt
    31561 gatataataa aagatgtgga agaattgtgt ccaaatgcat ggatggtgaa ttttacaaat
    31621 ccaacaggaa taataacaga ggctgtattc aaatatacta attttagaag atatataggt
    31681 ctatgcaatg tgccaattca tttaaaaaat gatgttgcca aactatttaa tgtagaaggt
    31741 gacagaataa gtatggattt tgcaggtctt aatcatatgg tttatggtct aaatgtatct
    31801 ttagatggag aagatgttac aaaagaagca attgataagt ttgtcaaagc agatataagt
    31861 atgcaaaata taaaggcaat tgattttaat gctgaatttg taaaatcttt gggtgcgata
    31921 ccttgtccat atcatagata ctactataaa actaaagaaa tgcttgaaga tgagttaaga
    31981 gagtttaaag agggaaaagc tagaggtcaa gtagttaaag aattggaaga acaattattt
    32041 gaattatata aggatgaaaa attagatgta aaaccacctc aacttgaaaa aaggggagga
    32101 gcttactata gtgatgctgc ttgtaattta ataagttcta tatacaatga taaaaaagat
    32161 atacaagtag ttaatacatt aaataatggt tctataagag attttaaaga tgaacaagca
    32221 gtagaagtaa gcagtgtaat aacaaaaaat ggtccaaaac caataagtat agggtattta
    32281 ccagattctg tgcatggatt agtaagccaa atcaaatcat ttgaagtatt ggcagctaaa
    32341 gcagccgtat atggtgatta tgaatctgct cttttggcac tttgtataaa cccattgatt
    32401 ccatctgatg acttagcaaa aactatatta gacgaaatgt tggaagctca taaagattat
    32461 cttcctaaat ttaatagata gttgtctata gaaagtaggt tatggtatga ctaaaattat
    32521 aataaatgca gatgactttg gatattgtga agctgtgaac tatgggatag tgtcagttca
    32581 taataatggt atagttaggt ctacttctat gatggcaaat atgcctgggg tagaacatgg
    32641 agtagggtta cttaaagaaa ataagtcttt aaattgtgga gttcatatga ctttaagttg
    32701 tggtagacca ttattgtcta acttaaaaac tattgttgat aaagacggtt tttttattag
    32761 gaggattaca gacgaaatta ttgaaaaaat ggattatgat gagatttata gagaactttg
    32821 tgctcaaata gatagagtaa aagggcttgg aatagatata tctcatttag acagtcacca
    32881 tcatatccat actttaataa gtttaaagcc agtaatagag aagattgtga acaagtataa
    32941 tcttccaata agaggtggat ttgaatataa tttagagtat tctaaaatag ttcctttaat
    33001 agatagtttt tataaggaaa atgtatgtga agaatatttt ataaaaaata tagacgaaat
    33061 aatgaagtat gatgtagtgg atattatgtc tcacccagct tttttagatg attatatttt
    33121 aaattctaca tcttatgcta ttgatagaac gaaagagcac aagatactta catctaaaaa
    33181 agtcaaagaa tttttagata agaatgattt agtcatatca agttatagag atatttagga
    33241 ggacgaataa atggatgaga agatgataga gatatctttt ggaataattg gatttgcagg
    33301 tgatgcgaaa gggctagcat ttgaagcaat aaaagaagca aagagcggga atatagataa
    33361 agctagagaa tgtattgaaa agtcgaaaga atcaattcat aaagctcata aattccaaac
    33421 agaattgata caaaatgaag ctaatggtaa taaaactgaa ataagtgtaa tacttattca
    33481 tgcacaagac catttaatga cagctatgaa ttttcaacaa ttagcagaag aatttataga
    33541 tgtatatgaa agattagaaa gtaagtaatt taaaattatt attaaaaaag agtgccttta
    33601 ataattataa aaattatttt tataattatt aaaggcactc ttttttattt aagtagagtt
    33661 tagtaatata gtattatgtt attgttactt taaaatttcg atttttcata attgtaaggt
    33721 atactagtgc caacaactac atcttcaatt ttttcaataa taagccaatc atccatattt
    33781 ccttgatggt caaaatcaag aggtgttatt tcttcaacat tttcaaattc aactaagcat
    33841 aaacattttt tatgccaacg aactttttgc ttttcggata aatttaattt tggttgattt
    33901 tcatttaaaa ttttagaaat ctcgtcttct gttaacttaa catagttttc tactttttta
    33961 acaatggctt ttgcagatat ttttgcagtt cctttttcca taaaataaag taactcatcc
    34021 ttaaatactc tactgtgtgg tatttttcta ccagcagcac ctctaatcac cattgttttt
    34081 gttccagcta agattttatc taaaaccttt tctccttttt ttcctgcatt atcacaatat
    34141 actaaatgta ccatttttcg aatcctcctt actaacttcc ttatctataa gttgcatttt
    34201 atcattgttc aactaaaaag tcattctatt tatatctaat tttttaaaaa atactattta
    34261 atatgagaaa accttatctg agctatatat aattaagatt aattaggaat ttttatcttt
    34321 ttacaaaata atattgacta aaaatagaaa aatgctataa taaatatatg cttatgataa
    34381 tcaatatcat ataagtataa taaacagcta ggagaaataa tcatgaaaaa aataaaatca
    34441 cttgcaatat ttatatctat tataactacg ttagtacttg ttacagcatg ttcagataag
    34501 aatgcagagg ataaagataa atcagagaca agagttgtac aatctgttaa aggagaggtt
    34561 aagataccat caaatcctaa aaaaatagtt gacatatcag gaagtagtga agaactacta
    34621 ttagcaggtt ataaacctat tgcaacagca aatgtagact catatgaaac tgataaatta
    34681 ccaagttaca taagagaaga acttaaagat gtaaagatag ttgggcactc aatgatggat
    34741 actatggata tggaagctat attagaagta aatcctgatt taataataat gagtcaaaga
    34801 caagaaaaaa tatatgacca attaaaagaa atagctcctg tagttatgat gaaagattat
    34861 gcaaatgact ggagaagtaa gttaactgat gtttcaaggt tatttgacaa agaagaagaa
    34921 actaaaagtt ggctacagaa gtatgatgaa aaagctacaa agttaggtaa agaagttata
    34981 gaaaagaatg gagaaaaaac ttatttacca gtgttggcaa gttcagggca atttatggta
    35041 tttagtgatg gtggaatagg tactctaatc aatgatgaca tgaaattagc tagacctaag
    35101 aatatgccaa aacaggatgg aataacacta ccaatgataa gtatggaagg tttaacagat
    35161 atagatgcag accatatagt tgtaattgct acagaatcag ataaaaaaga tttagaaaat
    35221 agtgctatct gggctcaaat aagagcagta aaagatggta atgtaacaat acttgattct
    35281 gctccatttt tcagtcaatc atacaatcca atgggaaaag agttattatt agaatcagtt
    35341 aaaaatgaat taacaaagta attcttaact tagtaggtgt gagataatga tattcatttt
    35401 tcacacctat ttttaataaa gcttaaaata aaaaatattt aatagatgat attatactga
    35461 ctattaaaag ggaaaaggag gtaggataat tgactaaggt aagcaaaaaa aatataactt
    35521 atttattgat attagtaagt atagttgtac ttgtatttgg aattttatta tccataacta
    35581 ttggggcaaa agatatgaat ctatcaactg ttatagatag cttgataaaa atggaagatg
    35641 gaataaatat tagaatagta agggatgtta gacttccaag agcaatagca gctacacttg
    35701 ttggaggttt tttagctgtt tccggggcaa taatgcaagg gataacaaga aatcctatag
    35761 ctgaaccttc tgttatagga attacacaag gagctacatt tacaatttca atatcactgg
    35821 tacttcaaaa aaaacttcct caacttatac atggaagttt tagtgtaatg atgtttgcat
    35881 ttattggagc aagtataagt ggattattta tatattttat aagttctaaa tcaagaggaa
    35941 gagttaataa tgtaaaatta gcacttgcag gagtagctct tggtacattg ttaatttcct
    36001 tggcatcagc aatatctatg tattttaacc tatctcaaca gttgagtttc tggatatcag
    36061 gagggcttgt aggagtgaat tgggaaggta taaaattgct atttatagct ggaggtattg
    36121 gatttatttt agctattatt atggctccaa gaataactat attaagtctt ggagaagaag
    36181 tggcaatagg attagggcaa aaaactaaca tagttagatt tgtatgtata gtacttgtga
    36241 tactaatgac tggagcatct gtttcagtgt ctggcaatat tatttttata ggtcttatag
    36301 ttcctcaaat agctaaagga atagtaggtt cagattataa gtatataata ccgagttctt
    36361 tagtattagg agctgtattg cttgtatata cagatatatt aagtaggatg ataaatcctc
    36421 catatgagac accagtaggt tctataacag cacttatagg agtgccaata tttatatacc
    36481 ttgttagaaa gggggagaaa taggtactat gaaaaatatt ataaaaataa attctaaaac
    36541 attgcttgtt atattaattt tagtggtact tatttttatc actcttctag tgagtttaaa
    36601 tatgggctca ttttctatag aaccaatgga tgttataaag acttttttag gtcagggtca
    36661 gcgtaatcat gaaattgcga tatttaaatt gagattacca agaatagtaa tagcactttt
    36721 ggttggttct gcattatcaa cagcaggtgt aatacttcaa ggagttacaa agaatgattt
    36781 agctgattct ggtattttgg gaataaattc aggtgctgca ttgtttgtag tagtttatat
    36841 ataccttatg aatggtaatg tatatgaagg tatgagtaat ctgactgtat ttacaatgcc
    36901 tattgttgca cttgtaggag ctttatttgg agcatttctt atatattctc ttgcatggaa
    36961 aggtggtata aattcgtcaa gattactact tattggtata ggtgtaaata tagcttttac
    37021 ttcaattttg actatatttc aattgaaatt tacaacacaa gaatttaata gggttatggc
    37081 gtggacatca ggaagtgttt ggggaactag ttggaaatat gtaatagctg tacttccatt
    37141 tatagtgatt tttatgggga taactattta taaatccaaa tatatagatg tattaaactt
    37201 gggtgatgaa gtatctataa gtcttggtgt agatgtagaa aaacaaagaa gaagacttat
    37261 aatatatgca gtaattttat ctggtgtatc gacagcagta gcaggtagta tttcattttt
    37321 aggtttaata gctccacata taggtagaaa aataataggt ccaaagcata aaagattaat
    37381 accagtatca gcattgatag gaacattatt gcttttaata gcagatacta tatcaagaaa
    37441 tcttctagca cctatagaaa tacccgtagg tatagtagtt tctataatag gagtgccgta
    37501 ctttatttat ttaatgttgg taaatgatta ggaaagggtg ttgttatgaa ctgtataaat
    37561 actaagaatc taaatgtatc atatggaaat acagatatta taaaaaatct aaatttaaat
    37621 ataccaaaag gaaaaataac tactatcata ggggctaatg gttgtggaaa atcgacaata
    37681 cttaaaacta taggtaggat tattagccct aagagtggaa aaatatatat aaatggagag
    37741 gatatctaca aaaagaagtc taaagaaata gcaaaggata tggctgtact tccacaaagt
    37801 ccacaagctc ctagtggtct tactgtttca gaattaattt cttatggaag gtttcctcat
    37861 aaaagtggat ttggtaattc tagtaaagaa gacagagaga ttgtaaattg gagtttagaa
    37921 gttactggaa ttgcagaatt taaggataga aatatggatg atttatcagg agggcaaagg
    37981 caaagggcat ggatagctat ggctttggca caagagactg atatattatt attagatgag
    38041 cctacaacat atttagattt ggcacatcaa ttagaaatac taaaattatt ggatgaatta
    38101 aataaaaaac aaggaagaac tattgtcatg gtaatacatg aacttaataa tgcagcaaga
    38161 tttgctgacc acatgatagg tattaagaaa ggaaaaatag tttgtgaagg tgatgcatat
    38221 gatgttatga cgaaagataa tctaaaagaa ttatttaata ttgatgcaga aatagcaaca
    38281 gacccaagaa caaataaacc aatttgtata acttatgaca tagtgtaaat ggtgacaaca
    38341 tggagaatca agaggcatta agacatgaaa aaatatggat tttattattt aaatattcga
    38401 tacctgcaat aatagcaatg atggtaactt cactttataa tgtagtagat agagctttta
    38461 ttggttctat ggagggcatt ggttctatag ctattgcagg tcttggtgta actatgccag
    38521 tatttactct aataatagct tttggaatgt tggtatcagt aggtgctagc acaagattat
    38581 ctataaagct aggtgaaaga aatagagaag aagcagagaa gatattaggt aatgctttga
    38641 cattatctat aattatctct ttaattataa ctatattagg attaattttt ttagaagata
    38701 tgctttttat tttgggtgct agtaaagact ctatttctta tgcaaaagac tatatgagtg
    38761 tcatattagt tggaagtata ttcaatttag ttgcattttc tcttaataat gcaattaggg
    38821 cagaaggtaa tccaaaatta gcagcaagga caatgattgt agggtgtgta ttaaacttga
    38881 tattggaccc tatattcata tttgtgttta atttaggtat aaaaggagca gctatagcaa
    38941 cagtactctg tcaaatagta gtattctttt gggtaacaca ttattttatg agaggtaagt
    39001 ccaatttaaa actaaaaata tgtaatttaa aattgaataa agatatagta aagaaggtat
    39061 ttgcaatagg tatgacacct tttgctatgg aggtagctat aagtataact cacatgttta
    39121 caaataattc gctaaaggtt tatggtgggg atttagctat tggggctatg acagcactta
    39181 catctatttt attgatgttt atgatgcctg tatttggatt gaatcaaggt atgcaaacta
    39241 taatatcata caattatggt gcaaaaaaat atgagcgtgc aaagaaaact ttgatattat
    39301 ctatcatagt gtcagttgtc atattatcgt ttgggttttt agtagtacaa gttttcccag
    39361 aagtatttgt aggtatattt aataaagacc cagatttaat gaatatagca gtaagaggta
    39421 taaatataaa tctaattaca ttgcctataa tgggaatttc tattgtaggg cctgtgtatt
    39481 ttcaatgtat aagtaaagtt aaacactcaa tgtttttaac tcttttaaga caatttattt
    39541 tatttatacc attaatcatt gtacttccaa ttcaatttaa tttagatgga gtttggttgg
    39601 cacagccaat tgcagatttt attgctatga taattgtatt attattctta aaaagggagt
    39661 ttaaaacaag tcaagtataa gaaatctaga aattaaaatg aaattagaag ataaaaagac
    39721 ttgtctttat aaagtgatta aaattatttt ataaagacaa gtcttttatt ttatttaacg
    39781 aaactatcca tactggtttc ttctagtgtt tttccaaaag tcattttctc aaatatttct
    39841 tgaggcagag gttttgaaaa aacatatcct tgtatcatat cacaattaat ttttttaaga
    39901 taatccattt gcaagattgt ttcaacgcct tctgagatac tattcatatt taattttttt
    39961 gtcagattaa ctatagattc tattatatga ttttcagcaa tattatctgc attaggtgaa
    40021 ctaaaaaaag cacggtcaag ttttaatgta tcaactttta tttcttttaa catattgagt
    40081 gaagaatatc cacttccaaa gtcatctagt gaacattgaa aaccttcttc atggatttgg
    40141 tctattatat taattagttt ttgtagattt tcaaatacaa gtgtttcagt taattcaatt
    40201 tctaagagct tagctggaat atcatattta ttacgaatca ttctgtattt ttctaaaaaa
    40261 tctatattat ttaaattagc acgtgaaaaa ttaactgaaa caggtattgg agtttctcca
    40321 ttatctatcc atttccttat catactacat actttttcaa aaacatagtg gtctagtttt
    40381 gtaataaaac catttttttc aaagaaagga ataaactcat ctggtggtat aagaccttta
    40441 tttggctctt gccatcttac taatgcttca gcacctacaa tagtattatc tttaagactg
    40501 attttaggct gaagatatac tataaattcg ttattattta atgcttcctc cattctattt
    40561 tccatttctt tttctttaat catttttaag cgttctaaat cactataaaa aacacatgta
    40621 taaagtggat gatttccaat atttccttta ttgttttttc gtgcaacatt tgcacggtct
    40681 tgaattgaaa ctaaaggtag atttgggtca tcaattttat atacacctat agatagagct
    40741 ataaaatact tgcattcttc atttttattg aaactgttaa tatcattagt aatgttttct
    40801 atgtaactaa gaatttcttt ttgaggaata gttttaataa gtacattaaa ctggtcatta
    40861 gaaactcgac aaagtaattc ttctggtttt agataattac taataacatc atgtatgtac
    40921 tttaatgttt tatcacctgc ttcactacca aaagaatcat taataagttt gaacttctga
    40981 atgtttatag ataccaatga atagctttct gatgaagatg attgtataat ttttttagct
    41041 tccatatcaa agcgtgcttt gctgtaacct ttagttacag agtctacata tgcgattttt
    41101 ataagttgtg ccctgttttt ttgatttata aacataatca atataataag caataaaaat
    41161 agtataacaa ttaaaatatt gattaagatt gcttttttta gaagtaaatc aaactgtgca
    41221 cttgctgttt ttgttggaac aatcgaaagg agatataagt tttcttcttg taatggaata
    41281 tagtgcattg ctttagaaat accatcatct aatgtataat acatagaacc agttttgttc
    41341 ttttttaagt ttgttttcat ttcatcaagc ttatttttat caacctgttt tcctttatgt
    41401 tcaatcatgt caaaaaaatt taccacattc tttggagcat ttttgtttgc cgaacttaca
    41461 ataaaatttc cattttggtc gataatttgg gaaaatcctt caccattaaa gctttctaca
    41521 cttaataaat ttctcatagt atcaatagta ttccaagcag caacagctcc aacaatttta
    41581 tcatctttgt atagtggtac agaatataaa attccatatg taccaaatgg tgatttaaca
    41641 ggcgtaattg tttctttacc ttgaagggct tttatataaa agtcttgtcc tttaacatta
    41701 cctgtatctt taagggcact tatgaaattt ccattagaat tgataatacc taaccaatca
    41761 aattcaaata attttaattt tttggataag tatttattta cttctttgtc actatcatta
    41821 acctcaaaat aagtatctcc cacagaatat agtgtcttaa atatactttt acatttcaca
    41881 tcaattgtgg tagaaatgct ttgtgaaatt tctataagat atcgttctgt ttcattatgt
    41941 gttactttat ttagattcat aataaaagtg acacatgtta aggacacaat tataaggagt
    42001 gtcaatagta aagtagctat tattttttta ttttttgtgt tctcaaagtt cattcttttg
    42061 tttcatcctc catcctctat ttgtttacaa ataagaattc tctcagacat attataccaa
    42121 atatcttttc atacaaagac attaaatttt atttatttga ctttatttaa tctttttagg
    42181 gagtagataa gatatattta tagtttaaat cgtattttat gatgttttaa gtaaaagagg
    42241 ataaaaagga actgttctca aaataacttt gatacagttc ctttttagta ttgtaaattt
    42301 ttataagatt agaaagggtt tttagtttat acatctacat aagtattatc tttataaaaa
    42361 atattttatt gtctattgca atctaaaatg tagatgaaat tctgtaaata ccaaattctc
    42421 tatgaccaag actttcagct ttggtatgct taccattaca gacttccact atttcattaa
    42481 atacttcttg acctatatct gctattttag cgccatctgt tataattcta cctgcattta
    42541 tatcgatatt gtctggcatt ttgttgtatg tatcactatt tccagtgatt ttaataactg
    42601 gtgaaatagg acttcctgtt ggagtacctc taccagttga aaagattaca atttgtgcac
    42661 cacctgctac cataccagtg atagaatcta tatcctgacc tggagtatcc ataaaatata
    42721 aacctttttt atcagtaggt acagtatcag catactcaag agcacctttg aatggcttgt
    42781 tgcctgcttt atacatacat ccaagtgatt tttcttcaat tgttgaaagt ccgccagctt
    42841 tattgcctgg agtaggttga ccactgcgta aatcttctcc catagtaatt gctctttttt
    42901 ctacatcact tacaaattta agaaacttat ccttcatttt tccatcttca aaacgagtag
    42961 ccaacaaatg ttctgcacca attacttctg tagtttcact tagtatgcta cttccacctt
    43021 catctataag aagatttgat gcaacaccta ttgaagggtt tgaagctatt ccacttgttg
    43081 ggtcagaacc accacattca agtgctaata taatttcact catatcaaat tcaactctta
    43141 cttcttttga tacttcacga gccattttac ctactatttc agctccctta gaaactgttt
    43201 ttaatgtccc accacattct tgtataacaa cataatctac cttttttcct gttgtagcta
    43261 tttcagatga taagtctttt gcttgaatac catcacatcc aagaccaact actaaaactg
    43321 cggcgacatt aggatttttt ccaaatccta ttaatgtctt tgctgtaagc tctatatcag
    43381 aaccaatttg acaacatcca tgttgatgag ggatggctat tgctccaggt acaagtgatg
    43441 ctattcttgt agctgtctca cttgaacata cagatgttgg aataactaaa acatgattac
    43501 gaataccaaa ttgtccattt tctcttaaat aacccattaa tttcatttta acttcctcct
    43561 attttttatc tccacgacca cgtgtacttt caatgttgtg tacatgaaca tagtcaccag
    43621 cttttatgtc tactgttgca attcctataa cttcaccgta tttgtaaaca acgtctcctt
    43681 tttttacatt ttctgtagcc atcttatgaa agacaggtat attatcattt actatgtaag
    43741 actttccatc aattgaaatt ttttcacctt taactaaagg tctgacacat gtaactagat
    43801 tatctttttc atttgcatga ataattatat tcattaattt tacctcctta agtattaatt
    43861 tacttcaata tttttatttg ttttaaaaat agcttttttc tttttttctc ttttatctag
    43921 ataggaaact aacattggac aacatattgc tgtaacaata atagcagcag caacctgtac
    43981 tgttgaaaca gctgcaattg tagctagagt agggtcgata gctgctaaag cttcaggagt
    44041 accagctgca tttccggctg ttgtacctgt agctgcacct actgctgggt gttctgcacg
    44101 tataagtttc attacaaaat acccacccat acctgttatt attgtaactc ctaaaccaag
    44161 tataactcca ggtaatccag cagttataat ttgattaaag tttaatgctg cccctaaagg
    44221 aaaagcgaag aaaggaatta ataatgttgt accaggtgca agaaattctc gtatatcttc
    44281 atcgagatta ccaagtataa atccaagtag tattggtata agtgctgcaa atagtgctac
    44341 tataggtaca tttgcaagtc cagttactcc aaaagcaagc attgtgaaaa aaggaccatc
    44401 atttagagat aagatagata ttgctccaac atctgtagag tctccatatt cacctgcaag
    44461 agcagcaaat agaccaccat ttgaattagt catagtagca actatggcaa gaggtgtaat
    44521 accaattata cctttaggtc caataaattt actaacaata atacctaata ctgcaccaat
    44581 tataaatttt gttgctgtaa gtactatacc tttagtcaat ggattaccag cttgtctgat
    44641 gttgatttga gctccattac atagacaaaa tagagcaagt atgctcattg caccagtttt
    44701 aaataaggat gttgtgaatc ctccaatttc aagagcttgt ggatatactg tattaaagag
    44761 tgctcccaat aacaggggac agaccataag tcctcctggt atctttttca ctgattttaa
    44821 gatgtgcatc tagtatcact ccctttcatt tttatatagg tatttaaaag caattactat
    44881 gccaatatat agagtttata tttttagtta ttatgattat ttttgataat cgattgaaat
    44941 actgtagatt acttataatt aaaagtatga ttgaggagaa ttttacatta aaaagattct
    45001 ttttatcata taattgtatt ttttattaaa aataaataaa cgtcttatgt attaaaatta
    45061 aacataaaac gttttgatat attaagtatg tattattttt aaacatcatt ttctatttct
    45121 tttaacttac gccatagagt agagcgagtt atctttagaa tttcacaggt ttttgtagta
    45181 tttctattat tttcgttata aattttatag atatattttt tttctaaagt ttttaaatct
    45241 aaattattat attcaaaatc agtattattt ttatcaacaa tattatttgt atattcatta
    45301 ctatcctttt ctaataaaat cgagtcaaat gattccacaa taacagccct ttccattata
    45361 ccttccaatt ctcttatatt accttcatat tcccgttgaa gaagtgcttt tttaatattt
    45421 ggagtgataa ttaaaggcgt cttattgtat ttgtttgaat atttatgtat aaaaaattct
    45481 gataatttta taatatcttc ttttctttct tttaatgaag gaagatataa tgttagtata
    45541 tttattctaa aataaaggtc ttgcctaaat aaaccgttgc gcatcagatt ttttaagtct
    45601 ttatttgaag cacagataat ttttacatct ataggaataa ctttattact gccaattctc
    45661 ataacttgtt tttcctgcaa taccctcaat aatcgacctt gaagttcaag agggatttca
    45721 cttatttcat ctaagaagat tgtaccttca tgtgctagtt caaatacgcc tgctttgcct
    45781 ttttttctag cacctgtaaa tgaaccttct tcataaccaa aaaactcact ctctattaaa
    45841 gatggaggta tggcagcaca atttacagca acaaaaggtg catttttacg cttactatag
    45901 ttatgtatgc tttgacaaaa tagttcctta ccaacgccag attcaccagt aataatcatt
    45961 ggtgtatcat aacaagcata tttttttgcg agttctatac aatcttttgt cttttcacta
    46021 gcatgtatta tatcatcaaa agtgtattta gcagagagac ctttatttaa taagctcctt
    46081 cttattgtat gttcaaaaga gcttatctcc ttgctgtctt gaaatgttga aacagctcct
    46141 tgaatttgac catcaacaat gattggaact ctatttgtaa taatttttgt acttcctata
    46201 ttttgtattt caccaatttg aggttccata gtttcaacca cttgtggaag aactgtgttt
    46261 ggaataacgt ctataacatt atgataaagt gcattttctt tttttatacc aaatattttt
    46321 tcggcactct tattaaataa tgttatttta aaatttttat caactgttat tattccatca
    46381 tgtacaaaat ctgtcatagc ttctatctgt aatcttcttt tttgttcatc cttggttgct
    46441 tcgagtattt gctctgcttg ttgaatggct ctaagtatgt tttcttctct agattcgatt
    46501 aatattccct tgcaattaag tctcttaaca atatgtgcaa cagtggtgtc tcctatatac
    46561 gtgtttatac ctttctttct gtacttttct atagcatcat aaatttcctc ttctttttca
    46621 atttcaatca tagttatttt cttattcaat atttcttcta taatatcgaa accgtagatg
    46681 acattattaa atccaattat tccaaatggt tcatctgaat tttttacctc tttgtagctt
    46741 tttataatat cataagcgtc tactttaatt tcaactatag gtatattgta agtggctttt
    46801 aacatattgt aagttccacc tcggcttatg ataattctag taccatgatt aatacttttt
    46861 tcagcaagag gtataccttc ttttagattg ccaaacataa catcaatatt tgtatatttg
    46921 ttttttctaa ctatatgaat tgatttttca tatgttcctt tagtgggagc aataacgagt
    46981 atttctttca taataatccc tccagatttc atcaaataaa cttaaatatt atcttatgac
    47041 taaattttat tagttatatt ttaatatttt actttgtatt taattataaa taaagtattt
    47101 taaaaagaac attataaaag actgtatcaa agttaacttt tagaattata aagtttcatc
    47161 tttttacagt cttttaattt acaatatcta tttatcaaat ctatctactt taaatagttt
    47221 catattttta ttttgtttgc caagatataa ttcacttaac attatacctc ctaaaattgc
    47281 aaagagtatg ccatttgctc cataacctaa gcaataccat agatttttat ttttattatc
    47341 tggaccaata aaacctaaat tgtctaaagt tgaagcaaaa caaccacaat atttatattc
    47401 aacttcaatg tcttttatat ccttaaacat acttttcaat ctttgttcta aaatatcata
    47461 cttttcatta gctaaagttt catcttctat atcatcaaaa cttacatctt caccacctat
    47521 aattaatcgg ttgtctttag tagttcttag ataattatat gggtcacagt tatctctaat
    47581 taaaatgtta tttttccaag aagcaatgtt tttaagtggt tttgtggcta tattaaaagt
    47641 atttgattta gttgcaaaat ttctttttgt aaataaactt gtattgtacc ctgtagctac
    47701 aattaatttt ttaccatgaa ccttgtatcc atacgatact tcagcagtaa ccttatcatt
    47761 tgataaatct acttttttta cttctgtatt ttcatatact tgaagaccat tttttaaact
    47821 tacatcaatc aaatggtgac tatatttata tgggtctaat tctcgtcctc cattctttgc
    47881 tatcaatcct gattttaaat caaagctaaa agggtttgta gattcatcaa tatattcaac
    47941 atcaaatcca ttttcttttc ttaagttata ttcttctttg atagccttaa tttcaagttt
    48001 attggcagta taaagtagag tatctcttct ggcataatca catttatttc catatagttc
    48061 tataaatgta tctaattctt caagtgctga agcacagaga ttgtatgctt ttagagcatc
    48121 ttttagagtc ataacctctg ttaaatctat caaattgtca tctaattcat actgtaacag
    48181 agaagttgtt acgctagtgc ttccatgtgc aatccttcct ttttcaagaa taacagactt
    48241 tatattgttt ttagctagat agtaagcaca aatacatcca gttacgccac caccaacaat
    48301 tataacatca gtatcaatat catcagtaag gtatggaaat tgtcttggaa ttttattaat
    48361 attagtaaaa ataggctttc cttttacata ttcttgattc atatatttca ctcctaaaat
    48421 ttattatgta tgagtgtatt attttctata gcaaataata ttatacattt taattatcta
    48481 gttatatggg tatgtataga taaaatgtga taacatttta gcataaaaca tatatataat
    48541 atattcataa tcaccttatt ttaagtaata tagtatataa tgtttgttaa caagtaaaaa
    48601 gattgaataa aagttaatta aaaatttaaa gtaggaggta aatttatgct ttcaaaagat
    48661 atagcttcaa aggtattaga aaagtgtcta attactggag gagattttgc tgagattttt
    48721 gaagaagaca ctataaataa ttctattagt ttaatagata ataaagtaga aaatgcaata
    48781 ggtggaagaa attatggtat aggaataaga atatttaaag gattaaagag tatatatgct
    48841 tatacaagtg acaattcatt aaatagtctg ttggatgtag catacaaagc tgctgttgct
    48901 ttaggtaaat tggaagatgg caaaagtgta atattaaatg acagtattaa aataaataat
    48961 atacataata taaaaattta tccaaattca ataggaaata gagataaagt aaatattatg
    49021 aaggttgcat ataagagtgc aaaagaattt agtagtgata tatctcaagt aagtgttagc
    49081 tatttggata aagaccaaaa aatattaatt gcaaatactg aaggtatata tgttgaagat
    49141 agaagaataa gaaccagact gggaataagc tcaattgcat ctaagggtaa tgaaaatcaa
    49201 actggatttg aaggacctgg aggttgtaaa gggtttgaaa tatttgaaga aatagatcca
    49261 gaatactatg caaaagagtc agctagagta gcacatacta tgttgcatgc taaaaattgt
    49321 ccagcaggta atatgatggt agcaatagat aatggatttg gtggagtaat attccatgaa
    49381 gcttgtggac attctttgga agctacatca gttgcaaaag gtaactctgt atttgcagat
    49441 aaattaggtc aacagattgc ctctacaaag attacagcta tagatgatgg tacaatacca
    49501 aactactggg gctctatgaa tatagatgat gagggaaatc cagctcaaaa aaatatactg
    49561 attgaaaatg gaattttgaa gtcttatatg atagataaac ttaatggtag acgaatggga
    49621 atgaatccta caggaagttc tcgtagacaa aactacaaat ttgctccaac ttcaaggatg
    49681 actaacactt atattgctgc tggagaagat aaaccagaag atattataaa gtcaatacca
    49741 gatggacttt atgctaaaaa aatgggtggt ggttctgtaa atcctgtaac aggagagttt
    49801 aattttgcag tttcagaagg ttacttaata aaaaatggag aaatacaaga gccagttaga
    49861 ggtgctagtt taattggaaa aggtagtgat gtacttatga atatagatat ggttgggaat
    49921 aacttaaaac aagctcaggg gatgtgtggc tcatcatcag gaagtatacc aactaatgta
    49981 ggtcaaccta tgataagggt aaaagaaatt actgtaggtg gaagataggg gggataattg
    50041 tggaacttaa aagttttaag gatatattat ttaaaaaggc tctaagtgaa ggttttgaag
    50101 agtgtgaaat atattattat acaggagaaa atttaagtat aaatatatat gaaggagaag
    50161 ttgagaaata caatcttgat aaatcttttg gtttatcttt tagagggaag gtaaatggaa
    50221 aaataggtta ttcttataca gaaattttag atgataaagc tgttgatatg ttgataaaaa
    50281 atgtaaaaga cggagtgaac accattgaaa atgaagatgt acaatttata tatgaaggtg
    50341 ataaacaata taatgctgta aagacttatt ctaaagaatt agaaaattta gaggcagaca
    50401 agctgattga tttagctcta gaaatggaaa gagagactaa ggcttattca gataaggtgg
    50461 taaatttatc taaatgtact atatcttatt ctgtatcaag taatggtata tctaatacta
    50521 aaggtcttaa tttaagtaat aaaactaata tgtttatagg atttgtagtt cctattatag
    50581 aagataatga gcaaaaatat gatggaatag gatataatat agcaagttct atcgaagaaa
    50641 taaaaccttg tgagatagca aaacttggtg ttgataatgc tttatctaaa gtaggtggaa
    50701 agagtattcc atcaggcaaa tataaaacta tattgtttaa tgaagctatg gtatctttgc
    50761 ttagcacatt ctctggaata tttaatgcag attcagctca aaaaggatta tctttattaa
    50821 aaaatagaga aggagatatg atagcatctc ctatagttac aatagttgat gacccacttt
    50881 tagaaaatgg tatggcatct actccttttg atgatgaagg agtagctaca tttaaaaaag
    50941 aagttgtttt aaatggaaag cttataactt tacttcataa cttaaagacg gctaataagg
    51001 caggtgtaaa gactacagga aatggaataa aatcttcata ttcatcacct ataagcatat
    51061 atccaactaa tttttatata gagaaaggag ataaatctct agatgaaatt atgcaggata
    51121 taggtgaagg attgatggtt actagttttg caggtcttca ttcaggtgca aattcagtaa
    51181 caggagattt ttctttagct gctaaagggt tttatattaa agaagggaaa aaagtatttc
    51241 cagttgagca aattacagta gcaggaaact attttgactt gttgaaagat attgaagtta
    51301 taggggaaga tttagaattt ccaatgagta gtataggttc accttcagtt gttattaaag
    51361 agctatcagt agctggaaaa gatgaataat taaaaagtaa ttttgtggat aaaaggtcat
    51421 gttaatttta attaatatgg ctttttatta tttaagtaga ttttattatc taagttatat
    51481 gaaaaagtcg tgatgcatac aattaatatc atacattaaa tttaaaggag gagatattat
    51541 gagtgatgca cattacaaca tgcacaagcg aaatggatat tcaagtgatg agccatatcc
    51601 agaaataaaa gttttaggtc caaataagta ttatgcagaa ttattgatgg atgactatgc
    51661 tggagtatca agtgaattta cgagtgtaaa tcaatatcta taccataatt ttgatttaga
    51721 tgaaaagcat agagagttaa atgaaatgtg ggtaaatata tctataacag aaatgttaca
    51781 tatggagata ttagcaaaga ctataagatt attgggtgga aatcctgtat atagaggttc
    51841 tacaagttct tgtggtgcat attggaatgg tggttttgta tgctatggag actctatttg
    51901 taacagatta aaattagatt tgcatttgga acatgtggct attaacaatt attataaaga
    51961 tataagtctt attgaagacc cttatataaa agctatatta aatagaataa tcctagatga
    52021 aaaacttcat gtaagtttat ttgaaaaggc aatagagaag tattgcaagt aaattttaaa
    52081 atttagttat tcattatttt attcatatat ataaaataac tatcatacat tttcttgaag
    52141 ggggttgctg tttatatgta ttatgtatat gtgaatgata taaatatagc agtatatgat
    52201 ttgaatccga gtgctaaaaa aactgtactt tttatacatg gttggccatt aggacataag
    52261 atatttgaat atcaaacaaa tatattgcca aaactcggat atagaacagt ttcaattgat
    52321 ttaagaggtt ttggtaaatc tgatgcaaca tcaggaggat atacttatag ccagttagca
    52381 gacgatattt ataaggtggt acatgctatt ggtttaaaag actttaccct tgttggtttt
    52441 tcaatgggag gagcaattgt acttaagtat atgagtttat ttaatggata tggagtgtca
    52501 aaattagtat tagctgcagc tgctgcacca tcatttgtac aaagacctcc agaatttcca
    52561 tatggtatga cacgtgaaga tgtcaataaa ttgatagcac aagcatgtac tgatagaccg
    52621 gaaatggtaa ctgattttgg agaaaaagta tttgcatcaa atccaccaga aagctttaga
    52681 agatggttta acgatattgg ttttagtgca tcaggtattg gaactattgg aactgctgta
    52741 tctttgagag atgaagaatt atttgatgat ttaaaatgtg taagagtgcc tactggtata
    52801 tttcatggga aattagatga aatatgtcca tatgaatttg cagtttttat gaatgaaaaa
    52861 atagaagatt caattttata tacttttgat tatagtggtc atgctatatt ctatgatgag
    52921 cttaaactat ttaatcagga atttttacag tttttagagg aatagttata ttttattatc
    52981 acttagaaaa agagtaatat tatgtgaagt gatttaagct aaattttatg atgtatttta
    53041 cactaaacaa atagggtttt agaacttgta actaagttct gagaccctat tattatatat
    53101 tcctaaaatt tgttacaatt tattctttat ctttcttaaa aattgtcgat atattaataa
    53161 tttcatatta aatttttatt tctattccaa taatgtcaaa ataatcgttt tagaaattta
    53221 aattatatgt gaaaaaagat aatctacatt attttattgt ggaaaataat agaaaatggt
    53281 acaaaatttg atttttaaga tttaaaactt ttttaaaaag tgctacaata gaccaaatta
    53341 ttactttcta tactcattaa acaggaggtg ggactatgaa aaaacataat attttatttg
    53401 tatcaactga tgataaaata aatatagata tatcaaaaca attggaaaat atatttggag
    53461 aattttgtag tatagataac ttgatatatg taaataggat aaatattgaa ctatcaagtt
    53521 atgaacttgt agtatgctca gacaatgata taaaggaata tatacataat aatattgata
    53581 aaaatatacc tattgtaata atacatcgta ctataaatat tgaaaatata aatcagataa
    53641 taagtataga aaatgattct gatgttatgg ttatagatgc ttataaagag tcagcagatg
    53701 aaactgccaa aataattaga aaactaggat taattcacat taatctaata ccatattatc
    53761 caggttgtga taagtctaaa tgtgagattg gaattattac aggaagcaga aacagcatac
    53821 cacaaaacat aaagcaaata attgacatag gcgataaaat aatcgatata aatacagtta
    53881 tagagatttt tacaaaacta aatatatcta tagataaatt acatattatt aaagaaaaat
    53941 atgatgaaga tacagtaagt ggatacaggt attacacaac tatgaataaa accatgaaga
    54001 gttttttgga gattatagat gaaggtattg cttctattga taaattggga aaatttatat
    54061 attgcaacaa agtattctct aatctaattg gaatagacca aaatgaaatt atatctaata
    54121 attttatgga tttatttagt gacaaggttg tcaaaaaaat attttttcaa gaggatgaag
    54181 ttaatgatga agtagtaaat ttaaataaca aaaaactgat aattaataaa gttaatgttt
    54241 atgaaaataa tgaacgaata aagagtatta taagtattaa agatataagt gcaattcaag
    54301 tacttgagga caagattcaa aataaatttc aagcaaaagg ttttgtatca aagtacacat
    54361 ttgagagtgt tgtaggtgag agcaaaataa taaaagaaaa aattaatatt gcaagaaaaa
    54421 tagcaattac agacttttct gtgttgatac ttggagaaaa tggaacagga aaagaaatat
    54481 ttgcccaagc aatacataat gaatctctaa gaaaaaacaa gccattcgtt gcagttaatc
    54541 tatcttcttt atcagataca cttattgaaa gtgaactttt tggttatgag gaaggaagtt
    54601 ttacaggagc aataaaaggt gggaaaatgg gtatatttga aagagcacat acaggaacaa
    54661 tttttttaga tgagataggt gatatatctt tagatgtaca gcaaagattg ctaagggtat
    54721 tacaagaaaa agaagttatg agaatgggtg gaagtaaaat tataccaata gatgttagaa
    54781 ttatagctgc aacaaataaa gatttaaaga aaaaaattaa agaaggttct tttagagagg
    54841 atttgtatta taggattaat gtattacata tagaaatacc tagacttaga gagcgtaagg
    54901 aagatatatc tcttataagt aagtattttt tagatgaaat aaatagcaac aaatgtttta
    54961 cggaagaatc aatgaaggct ttaaaattgt atgaatggcc aggaaatgta agagagctta
    55021 aaaatttagt ttattatatt gatactatag ttgaggaaga tagagtagat tatgagcatt
    55081 tgccagaaca atttagattt gaaaaaaaca atactttagt taatgaaaat tttgactcaa
    55141 ttatcctaga tttcaaacaa tcgaatttct ttgaggaaag tatatgtata ttgactagtg
    55201 tagaaacttg gaataataaa aatatattat taggaagaaa taaactgcaa gaaattttaa
    55261 aagaaaaagg tatagtttta agtgtagacc aaattagaaa aagaatagat aaattaaaga
    55321 gtcatggttt acttttatct ggagtaaaaa aacaaggtag ttttataact gatgagggca
    55381 agaactttat atcatatata aaatttaagg gagtgatata gggggctaaa aaggcaaaat
    55441 accctaaaag aatccctata gtagatagaa ataaataaaa ttatttttaa gattaagata
    55501 attcaaaaat attgaataaa taatctaaaa agattatttt taataaaaca gtagtaaata
    55561 tcaactttac taccgttttt attttttgaa agatttattc tacaattaaa atttatattt
    55621 tggcatatca attgctatat agaaaaaata taaaaaattg tagaacttgg aggatattgt
    55681 tatgaagtca gcttataaag gatatgaagc ctatagttat ttagaaaaag gaaaagatat
    55741 ttcatctatt gagatgtgta aaggagataa aagagttaaa gaatacctta ttgaattaga
    55801 tgatattcaa gaatctaggg ttaaaagtat agttgatgaa aaaatattta tatcattaca
    55861 tgaacatcca gtgttatttc cagaatacct agaaagagat atatttgaat acaatagaga
    55921 aggtaaacaa agatgtgctt atgaagcatt atcaagagga tattatgatg ctatatttga
    55981 taatttaatg gatggtgtat gtacgataac atcaaattca ggatggaaat gggatgatat
    56041 attaatagat ttgggtatga gactatgtga tttagctcat caagattttg tcataaagtg
    56101 tgaaaaagta gaagatatat acagagctaa aagtgaaggt aaagtggcat tgatacctac
    56161 actagaaggt gcagcaccaa tagaaaatga acttgataga atagatatac tatatggatt
    56221 tggtataagg ttaatgggta taacatacag cgaatccaat gcattaggtt caggactaaa
    56281 ggaagaaaaa gatggaggtc ttacaaattt cgggaaaaaa gctgttgaaa gaatgaataa
    56341 aattggaatg gcaatagatt gctctcacgt tggagttcaa actacacttg atgttataga
    56401 atatagtaag gacccaataa tattaagtca tgttggggca agaagtttat ggaatacaaa
    56461 gagactaact ccagatgaag tattaatagc atgtgctaaa aaaggagggg ttataggcgt
    56521 agaagcagca cctcacacta caataacaga aaagaataaa gaacattcaa tagagtcatt
    56581 tatggaacat tttgagtata ttaaaaattt agtaggaata gaccatgtag cttttggacc
    56641 agatacagta tatggtgacc atgtaaaatt acactcagta ctagctacta aatttgatat
    56701 aaaaaaaata acaggtacaa aagaacatcc aaaagtagaa tatgtaaaag gtcttgagaa
    56761 cccgacagaa acttcaaaaa acattgtcag atacttagta aaacatggat atagtgatga
    56821 ggaaatagaa aaagtactag gtagaaatat acttagagta ttaaagcagg tttggaaata
    56881 gatatattag aaatattaac aaaatctgag gatttatagg gaggttttat aaatggatta
    56941 tttaaaatta gctaatcacc cacttttgtg gatagcgagt acaatagccg tatcaatagt
    57001 agtggtacaa tcccttatat ttgctataaa atcttgcaaa gttggtaaaa caatgggaat
    57061 aacagataaa caaataaagt cagctgttaa gagtagtgct atttcagcta ttggaccttc
    57121 aatgactata tttgctggaa tggtatcact tatagtaact atgggtggtc ctatagcatg
    57181 gatgaggtta tcgtttatag gttctgtaat ttttgaatca atgtcagcag gatttggaac
    57241 agatgcatta ggtataactt taggttctcc tgaaatgaca aaacttgcat ttacaaatgc
    57301 agtttggact atgatattag gttctttagg atggataata tttacattac tatttggaca
    57361 taagctagat aagataacca atgtcatatc tagtggaaag aaatcattta taccaataat
    57421 atctctaggg gcaatgttgg gttcatttgc atatctaaat gctgataggg tgttgcgttt
    57481 tgataatgga acaattgcat gtataagtgg aatggctata atggtaatat tgtgtatact
    57541 tgaaaagaag aaaaatataa aatggctaag agagtggggg cttacaatat caatgtttag
    57601 tggaatgata atagcctcag taatataagg ggggagtttt atgagcaaag taaaatctat
    57661 atacaatgaa gaatatttac cttttatgat aagatatgga agattgacac tatctttggg
    57721 tattatagca gcattagttc ctggaataat tttgagcttt gggtttggta ttatgcctcc
    57781 aatatcagca ttattagcaa gtacaatggc aattgtcagt atgagtgctc caaactacat
    57841 aatagaacca gtttcttatt caccaatctt aggtatacca ggaacttata tgagttttct
    57901 ttctgggaat atatctaata tgaggctacc atgttcaata gcagctcaaa aggcagcaga
    57961 agttgaatca ggtacagaag aaggctcgat aatatctaca ataggaatag ctgtatctat
    58021 tttagtgaat ataattatac taactatagg ggtaatttta ggaggaagtg tattatctaa
    58081 aattccagct gaagtagtag agaaattaaa cttaatttta ccagctctat ttgggtcagt
    58141 ttttggacaa gtatttttac aagataaaaa actaggtcta gtagcaattg taatatctgt
    58201 attgactatt atattatcaa agcaaggtat aataccacag tctttagtag ttcttatatg
    58261 tgtatttggt actatattaa ttgcaagagc tatgtataaa gataagctta gtgactaatt
    58321 acaatgaaat aataatgaat tttcaaatat aaaatacaat gatttgatta cgcaaaatta
    58381 tatgaagcag gaactctgtg actttagtca tgggaggttc agtttaaaat ataaaaatta
    58441 cattaagact atttaaaaac tggtttttaa ggagggaata ttttgatgta tgatttaatc
    58501 ttaaaaaatg gatttataat agatggtaca ggtaatcctg gtttttatgg agatatagca
    58561 attaaagaca acttaatagc aaaaatagat tataagataa atggcaacac aaataaagag
    58621 attgattgct gtggaaaagt tataacacct ggatttattg accctcatgt tcatgaagaa
    58681 atagtagcaa tactagatgg taaatttgaa aagtttctaa aacaaggagt tacaacaact
    58741 ataaatggta attgtggaca ttctataaca ccatattctt ctgaaaatgt atatgaatat
    58801 atgtataaaa atggtctatt acttgaagaa gaaaaaaagt atcttataga taaaaataaa
    58861 tattggaata attttacaga atattgtgac cttatatcta aaagtggtat ttctatcaat
    58921 atgggatttt tgttgggaca tgggactata agatggagtg ttatgggagg ttctaaggat
    58981 aggcatccta cagaagagga aaaaaatgaa attacaaata taataaatga tggcatgaaa
    59041 agtggtgctt ttggaatatc tacaggattg gcatatatac caagtaagta tgctgatatt
    59101 gatgaacttg ttgatattgc aaagcagatt aaagaatatg atggtatata tacatctcat
    59161 atcagagatt acataggaag atataacgca gtaaaagaag ctatagaggt tgggcaaaaa
    59221 agtggtgcta gggttcaagt atctcactta agcccagttg aaatagaagc atttgatgag
    59281 atattaaagg ctaggtataa tggtgttgat ataatggttg atacagttcc aagaagttct
    59341 gggcattgta tgaagaaaaa aagagtaatt caatttatta tggcaatatc atcaagttta
    59401 tttgaattag gtatagacgg ggtaatggat gctcttaaaa atgaagaggg tagggcactt
    59461 atattaaaag aagcatttat acttggagat agggggagta taatacttct aaacactaag
    59521 gatattgata tggaaaagaa atcaatacgt gaaatagcca tacaaaaaga tatagatgag
    59581 gacaaattat tactagattt acttttagat ggagatgaag agcttatctt ttgtttagga
    59641 ggaatgtata gatctgattt cccagataaa ctacatgata ataagataat tgataatcca
    59701 tttgttatgg ttggttcaga ttgtttattt agtgtgggtg gggatatgtc atggtttgaa
    59761 ctacaaagga gaggagcttt ttcaattttc ttcaatatgt acagaaagtc tggcgttaga
    59821 ttagaagaga ttgtaagaag agttacttca ttaccagcta ggcagtttaa aataaaaaat
    59881 agaggtattc ttaaagaagg gttgatagct gatatagcag ttattgagat agagaactat
    59941 agttatccta ggtcagaaga tattgatttt tcaaagccac aatcactggc taaaggtgtt
    60001 gaatatgtaa ttgtaaatgg aaaaattgca ttagaagatg gaaatattac tgagaataaa
    60061 tgtggtgagg tattaagaag ataaggtttt aaaaataata gggatttaga aagcaaataa
    60121 atgtctaagt aagtaaagac gaagtttgag atttatttaa ataagaatca tgcttcgttt
    60181 ttacttatag tattaagatt tatttta
//
LOCUS       DAMKOJ010000014        59774 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000014 DAMKOJ010000000
VERSION     DAMKOJ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59774
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.015"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(122..457)
                     /locus_tag="PC592_000973"
                     /pseudo
     CDS             complement(122..457)
                     /locus_tag="PC592_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
     gene            complement(583..1587)
                     /locus_tag="PC592_000974"
     CDS             complement(583..1587)
                     /locus_tag="PC592_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4054980.1"
                     /translation="MRFKRILIFILTVAMTAGMLVGCDSNQSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFETGFKEGVKFSNSSIKDISVEYADVFKDRK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIGAVRTKNKKVIATNKDQHELAPENVISSI
                     VKDFENSTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVSKNNK
                     "
     gene            complement(1875..2723)
                     /locus_tag="PC592_000975"
     CDS             complement(1875..2723)
                     /locus_tag="PC592_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF4054981.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEKEYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEGREILYIAGSATATGTYQSAVM
                     AKNDVEGKIYTYDSNLLCMGTGLLVIKAGELASEGKTVDEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMEDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(2758..3228)
                     /gene="trmL"
                     /locus_tag="PC592_000976"
     CDS             complement(2758..3228)
                     /gene="trmL"
                     /locus_tag="PC592_000976"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDF4054982.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPETLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(3422..4279)
                     /gene="nth"
                     /locus_tag="PC592_000977"
     CDS             complement(3422..4279)
                     /gene="nth"
                     /locus_tag="PC592_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDF4054983.1"
                     /translation="MKNVNLKEINKKEVIDKEEINKKGIDKKDVTEKEKINKKSEHDK
                     KTKNSSSSKDTQKLSKGIKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNYGTAF
                     ELLIATILSAQCTDVRVNKVTSELFKKYNTAKDFANLSIEEISKEIKSCGLYKSKSQK
                     IKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSN
                     RIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCN
                     YYKELNETK"
     gene            complement(4477..6714)
                     /locus_tag="PC592_000978"
     CDS             complement(4477..6714)
                     /locus_tag="PC592_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4054984.1"
                     /translation="MKYNNTSEINPLDCILGQERAVEAMELGLKINNPAYNIYIAGES
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQDYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEGNEEGIARFIASQCDKNNLRHFTKSAVEEVVKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVPIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVQDGKFKIYTVERVEEAIEILTDVKFEEIRKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(6820..7734)
                     /gene="queG"
                     /locus_tag="PC592_000979"
     CDS             complement(6820..7734)
                     /gene="queG"
                     /locus_tag="PC592_000979"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDF4054985.1"
                     /translation="MNNRELKEFCNLIGLNCVGVAGVDKYDNLENILKDRYKKGYLTG
                     MEEPIIENRINPRNIMEDANSIIVCAFPYYINRQEKNKNSNLSKYCHGKDYHIVVKKF
                     LQQICDYISKKVTDFKYKIFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSQE
                     EKAVLKSGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGKNIIKRNMEIILDKYND"
     gene            8492..8896
                     /locus_tag="PC592_000980"
     CDS             8492..8896
                     /locus_tag="PC592_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF4054986.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYNISYNIFEK"
     gene            complement(9130..10125)
                     /locus_tag="PC592_000981"
     CDS             complement(9130..10125)
                     /locus_tag="PC592_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF4054987.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADDVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(10408..11244)
                     /locus_tag="PC592_000982"
     CDS             complement(10408..11244)
                     /locus_tag="PC592_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDF4054988.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     NEKDIIKFQEIRKANNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIDRLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(11727..12290)
                     /locus_tag="PC592_000983"
     CDS             complement(11727..12290)
                     /locus_tag="PC592_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4054989.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(12388..13317)
                     /gene="glsA"
                     /locus_tag="PC592_000984"
     CDS             complement(12388..13317)
                     /gene="glsA"
                     /locus_tag="PC592_000984"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDF4054990.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(13915..15582)
                     /locus_tag="PC592_000985"
     CDS             complement(13915..15582)
                     /locus_tag="PC592_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HDF4054991.1"
                     /translation="MKKINLKIEGKDKEYSLEENSHGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEVDVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDNNKRVILIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLED
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(15656..16411)
                     /locus_tag="PC592_000986"
     CDS             complement(15656..16411)
                     /locus_tag="PC592_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDF4054992.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSDLCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELRGFDIRYFNLHLGYV
                     MTNRVRRNRDKYLENSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDDYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLDNIVGEG"
     gene            complement(16421..16957)
                     /gene="lepB"
                     /locus_tag="PC592_000987"
     CDS             complement(16421..16957)
                     /gene="lepB"
                     /locus_tag="PC592_000987"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF4054993.1"
                     /translation="MNETIKEEIVEWIKIIITALFLAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(17123..17659)
                     /gene="lepB"
                     /locus_tag="PC592_000988"
     CDS             complement(17123..17659)
                     /gene="lepB"
                     /locus_tag="PC592_000988"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF4054994.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDVDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHAI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(17759..19069)
                     /locus_tag="PC592_000989"
     CDS             complement(17759..19069)
                     /locus_tag="PC592_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDF4054995.1"
                     /translation="MTKLPKEFLEDVEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLGLFDLNQISWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINVSRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSHAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRRENLYLLPK
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKETSGVIKNHYPKGLRKVF"
     gene            complement(19148..19864)
                     /locus_tag="PC592_000990"
     CDS             complement(19148..19864)
                     /locus_tag="PC592_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDF4054996.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVILLWKINLDKLE
                     KYMNNSKKVFFGNLRKKKKK"
     gene            20101..21372
                     /gene="sleC"
                     /locus_tag="PC592_000991"
     CDS             20101..21372
                     /gene="sleC"
                     /locus_tag="PC592_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HDF4054997.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTTYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRFFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVRIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(21846..22502)
                     /locus_tag="PC592_000992"
     CDS             complement(21846..22502)
                     /locus_tag="PC592_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054998.1"
                     /translation="MKKGDFIWSGILICIIAVLAIPSSREVFMEATGAHPYIGGFFKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGIVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(23703..24113)
                     /locus_tag="PC592_000993"
     CDS             complement(23703..24113)
                     /locus_tag="PC592_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4054999.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEKDL
                     EKIKTEGLKIMKPITIKNEDGSQISIAYNYAAID"
     gene            complement(24329..25687)
                     /locus_tag="PC592_000994"
     CDS             complement(24329..25687)
                     /locus_tag="PC592_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF4055000.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNASTENYTLKKAGDSTGKNNSDKFEIMSSIE
                     NIMMLEMLGILSFIVTIIFSILLCFRYIKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGIGLVFATENKEINEVESF
                     GLTKNEKSVLSISSDSTELYTPKVDSNISVSMSKVSMNKSSESKSYEDISMNKVRNTE
                     NYSEVSVEKSSKSNDYEDVLYTPSAEYSIQKNNYNEGVLVISRKGNLLAVNNIQYRTS
                     IK"
     gene            complement(25698..26057)
                     /locus_tag="PC592_000995"
     CDS             complement(25698..26057)
                     /locus_tag="PC592_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4055001.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(26262..27041)
                     /locus_tag="PC592_000996"
     CDS             complement(26262..27041)
                     /locus_tag="PC592_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDF4055002.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKMGDIFVNGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICENKDNLGVFKSMSASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
     gene            complement(27503..28114)
                     /locus_tag="PC592_000997"
     CDS             complement(27503..28114)
                     /locus_tag="PC592_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055003.1"
                     /translation="MKMVKKLILSSIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGIADALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANNLVKSYVTDEKNYDKKEKEVQDDMAK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(28206..29195)
                     /locus_tag="PC592_000998"
     CDS             complement(28206..29195)
                     /locus_tag="PC592_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDF4055004.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNIPV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGVGGQGEPQLEAMIEARNLDEVRVFSR
                     NKENREKFVEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVFNGNLVKKG
                     ALISAVGSYMPDMQELCPICLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGMDWKW"
     gene            complement(29263..30120)
                     /locus_tag="PC592_000999"
     CDS             complement(29263..30120)
                     /locus_tag="PC592_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HDF4055005.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLKNASIN
                     LNNKEAVSVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSNKI
                     VERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSIKV
                     RYYTYSGGAHGFYQDTAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELEKK
                     DEENIGIYNFKGIKENQNFYLQDDNLVIYFDLYDITPYAAGIPEFSINKKLISSMLKP
                     EYVDLFDLK"
     gene            complement(30226..30822)
                     /locus_tag="PC592_001000"
     CDS             complement(30226..30822)
                     /locus_tag="PC592_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HDF4055006.1"
                     /translation="MGRFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGCQMKLCADKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(30862..31665)
                     /locus_tag="PC592_001001"
     CDS             complement(30862..31665)
                     /locus_tag="PC592_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDF4055007.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIERKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSIFPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSNTKYKYVKPAIYKR"
     gene            complement(31701..32141)
                     /locus_tag="PC592_001002"
     CDS             complement(31701..32141)
                     /locus_tag="PC592_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDF4055008.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPEADYNERTCIIITKVDEYQVGIIVDRVIDVIPI
                     ENLNLLATTNSNNININKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(32154..34256)
                     /locus_tag="PC592_001003"
     CDS             complement(32154..34256)
                     /locus_tag="PC592_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDF4055009.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEDYVSTLELSSSMKSKDNASLESTDEIEVIDLNFAYREG
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFLDFYPKDVETNAESTEYIKNYGFYIQ
                     FVAKEDNSIVYKIIEENLYVKEYINISKKEIEMKSTSNNNEVENKLKDSNKVSKSYKN
                     NYTEDELQEDVLNEKTDIEKDGLSGENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKSTRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLTEPFMHLIRNAMDHAIEPIEERIAKGKKEVG
                     KIVLSAENLGGEAVISISDDGRGIMKDKILAKAKEQGLLKHQTNEYTDEEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKPDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEENKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMHGNMIIIENENKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(34427..36130)
                     /locus_tag="PC592_001004"
     CDS             complement(34427..36130)
                     /locus_tag="PC592_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HDF4055010.1"
                     /translation="MKREVKLSKLAIVLLVIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQNIIFSSDYINSQEKMDSLI
                     NEFQEDIVARSNAKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVDFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVKIAKETANALELVVNGVEKTTDYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKEREVRESSW
                     V"
     gene            complement(36156..37115)
                     /locus_tag="PC592_001005"
     CDS             complement(36156..37115)
                     /locus_tag="PC592_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4055011.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKALTKDNFKVKKAFNAIEAKK
                     FIEEFIPDIILLDIILPDNSGFDFCKEVKSNARTADIPIIFITSKNADTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTIISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEDAKILSERIRKEIKEFDFNYKENKIKCTITLG
                     VVEVNSNISLEENISLADKVMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(37251..37769)
                     /locus_tag="PC592_001006"
     CDS             complement(37251..37769)
                     /locus_tag="PC592_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HDF4055012.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMITNCMYIVVTEIKDLVVGFV
                     VDRVDDIISLEKSEISPPPRVTIEYSDYFVSGIGELDGKVITLLDLEKLLTDKDEILI
                     DELINGFDCTIM"
     gene            complement(37812..38297)
                     /locus_tag="PC592_001007"
     CDS             complement(37812..38297)
                     /locus_tag="PC592_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HDF4055013.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKYKFADTGIKELIKSMENIGANRIYIKAKIAGGAQMFLGNSN
                     SAIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELIVDSINKGKKK
                     L"
     gene            complement(38294..38911)
                     /locus_tag="PC592_001008"
     CDS             complement(38294..38911)
                     /locus_tag="PC592_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HDF4055014.1"
                     /translation="MINYLELDDAHIDALREIGNIGSGNAITSLASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEVP
                     LDDIEEIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFVENKFKMSDNYFTSHILMIPEMSSLREILVKLGLEI"
     gene            complement(38976..39338)
                     /locus_tag="PC592_001009"
     CDS             complement(38976..39338)
                     /locus_tag="PC592_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF4055015.1"
                     /translation="MGNKILIVDDAIFMRMIIKEALGKSGYNNLVEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVDAIKLGALDFI
                     VKPFKTETLVKVVNNALK"
     gene            complement(40073..40570)
                     /locus_tag="PC592_001010"
     CDS             complement(40073..40570)
                     /locus_tag="PC592_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF4055016.1"
                     /translation="MNYEIVEISEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKSDKTIGLYTDYQGDFTSPYNFVACCEVNSNSDKDKNLEELNTNNTVGEIII
                     SKVIPAGKYAKFVIAGGQKEVGDFWLEFWQMDFDRTYVSDFEEYQSNTFDTNKHEIHI
                     YIGIK"
     gene            complement(40727..41638)
                     /locus_tag="PC592_001011"
     CDS             complement(40727..41638)
                     /locus_tag="PC592_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF4055017.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMMKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNIINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKEEVFSRKVIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDNTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLKELSKIYSL"
     gene            42365..43216
                     /locus_tag="PC592_001012"
     CDS             42365..43216
                     /locus_tag="PC592_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF4055018.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVIGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKNTKEI
                     KSTKGEC"
     gene            43220..43690
                     /locus_tag="PC592_001013"
     CDS             43220..43690
                     /locus_tag="PC592_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055019.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            43703..45013
                     /locus_tag="PC592_001014"
     CDS             43703..45013
                     /locus_tag="PC592_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4055020.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYNNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKEGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHSSDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVKITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIVPAK
                     AMALTVVDLLFDNAKNAKDILDAFTPVMTKEEYLTFLEKHDKTL"
     gene            45568..47109
                     /locus_tag="PC592_001015"
     CDS             45568..47109
                     /locus_tag="PC592_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF4055021.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SVVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAKLDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMIFNIPLGPGIL
                     PSYSM"
     gene            47144..48250
                     /locus_tag="PC592_001016"
     CDS             47144..48250
                     /locus_tag="PC592_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF4055022.1"
                     /translation="MLDKNRLINNFIDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPVLDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPENLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDRVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGIVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(48557..49843)
                     /locus_tag="PC592_001017"
     CDS             complement(48557..49843)
                     /locus_tag="PC592_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF4055023.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDNDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFKLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRYSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAISENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(49966..53064)
                     /locus_tag="PC592_001018"
     CDS             complement(49966..53064)
                     /locus_tag="PC592_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF4055024.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKALRINDISNMK
                     CYEAIQGRDSPCEFCTNSILKEDGYYVWENTNTLINRHFILKDKLIKWEGKLARIEIA
                     LDITEKENISKSISEKLEIKELLVGCIKHLITESSFSDAVDLVLSSIGKFHKADRAYV
                     FEVSEDRKKVINTYEWCNEGVDEQKQLLTNLDIKELKNWFLLFKQKGFIIIDDVEDIK
                     EEHPMEYEILKPQKIKSLMASSLKEDDKIIGFIGVDNPRKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTSAYNRNRYIKYIDTFQKDKVKSIGVVFIDINGLKDIND
                     NFGHASGDAIIMSVSVMIQKYFHSYYVYRIGGDEFVVLCEDISKQLFEELVSWLTEEL
                     KDNMECSAAVGSIWSEDDIDIHKLIKVADERMYQDKKRYYNKIELRNNEMKVVSDLSD
                     STNNISLKCRDLDNEVYFDDLMIKGYSKAYEKLAYNTYDIILSICMDTNLITPIYQSE
                     SNILNFPIKENIEKIFSYIKKHLIHPDDIILFDDNLLLKSIDSPNNSKQGDLELNFEY
                     RHLGIDEKYHWALLYILKISSKNNLGEKQTHILVAIKNIDYLMQIHKNQKDTLTGLYN
                     YESFCEQTSLMLKRYPGKRYAIIMMDIDKFKVINDIYGIRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDREIHKVIYNIKNNLNRKKFEYMLVPCFGVYKILDNH
                     IPITSACEMAGYAHKKVKKQSINHYIFYDDTIRNDALEEKHMEREMEYALENGQFHVY
                     LQPKYNLNTNKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIKLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYGIPKSFLELELTESLFIKN
                     IKLFTKVIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNGEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSDDFEKLLY
                     QK"
     gene            53787..53927
                     /locus_tag="PC592_001019"
     CDS             53787..53927
                     /locus_tag="PC592_001019"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055025.1"
                     /translation="MLYVVGICFCIAGFIGHYPAFAGATLSFFATTMIAVNQGKTKKK
                     MK"
     gene            complement(54216..54920)
                     /locus_tag="PC592_001020"
     CDS             complement(54216..54920)
                     /locus_tag="PC592_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055026.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQGNINNDAPKSFEVKNLKIDYENHTVLINDEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(54911..56518)
                     /locus_tag="PC592_001021"
     CDS             complement(54911..56518)
                     /locus_tag="PC592_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HDF4055027.1"
                     /translation="MKKERLQHEDLKEYDYDEDVYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGIACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESS
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPVYDEEGKDKWK"
     gene            complement(56774..57952)
                     /locus_tag="PC592_001022"
     CDS             complement(56774..57952)
                     /locus_tag="PC592_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055028.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(58176..58670)
                     /locus_tag="PC592_001023"
     CDS             complement(58176..58670)
                     /locus_tag="PC592_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF4055029.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTRIKENEKYKNSINKI
                     KQQK"
     gene            complement(58671..59432)
                     /locus_tag="PC592_001024"
     CDS             complement(58671..59432)
                     /locus_tag="PC592_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF4055030.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFIGVSIAVGMFLVLGLYFKLGGI"
BASE COUNT        19591 a        10582 c         6230 g        23371 t
ORIGIN      
        1 cagcaattca agtagtattg gataggttct atcctatctc tacatataag tttccctata
       61 tgctgactat tttagctact aactcatgac taaagtcacg agtgtgcgta gctatttttt
      121 aatcaaaatc ttcgtcagcc ctttttaagg ctgatagtac attattatta tatgattcat
      181 tatttaagtt ttcagtatct aataatactc caacagtttt tcttacatat aaatcatctt
      241 ctgtctcatc ttctttattc ttacttttac tatttgattt atccttttct gctaaagtcg
      301 gtacattttt agactcactc tgttttgatt tagcactatc tatattagaa ttattcttat
      361 ttactttatc aaacccaaaa tcaaaattac atatagctaa tataaaaatt gtaaaaacta
      421 ccacaaagca aaccatcaat atccttttta ttttcacaaa attcactccc tgatttagat
      481 aggcattacc tacctctaca tatgcctttc tatatatgtc tattataaca gccagttcaa
      541 ctcataacta aagtcataag tattcctgga tattatagaa gattatttat tgttcttact
      601 aacatattct aacacatctg gaggaatatt ttgagaacta ttttgggcaa gcccagtact
      661 tccagactta actgtatttt ctataacttt tccaccttta taatttcctt ttacaaagct
      721 ttgtatcaaa ttataagtag aattctcaaa atcttttaca atagaactga taacattttc
      781 tggagctaac tcatgttggt ctttatttgt tgctataact tttttatttt ttgttcttac
      841 tgcacctatt acagcttttg aatcatcttc agtagtagaa aaaataatat ccactccatt
      901 atccatcatc tttttagcta tagattctac tgattttcta tctttaaaaa catctgcata
      961 ttcaactgaa atatctttta tgctactatt agaaaactta acaccttctt taaaacctgt
     1021 ttcaaatttg tctctactcg aactctttgt tccacctata aaaccaacct tatcgctttc
     1081 agtcatcttt ccagcaatta atccagctag gtatccagat ttattatctt cataagaaat
     1141 tgaagttata ttagaaggtt gcttgtcata ctcatagtct ataattgcaa attgttgctt
     1201 tggatatttc ttggctacca tctccaaagg ttttgcaaat ctagctccta cagctataat
     1261 taaatcgtaa ttgtcattac ataaaatatc tatactatta gaaaaagttg atgaatcatc
     1321 tgattccact ttgtttgtgt ctatattaag tttcttttga gcattgttta atgctaataa
     1381 agctgaatta ttcatagctt cattatttgt tccttcaata tctagtatca tagatacaga
     1441 tttttttgaa ttacttttgt cgcttatatc acttttatta tctttgctag aactaggatt
     1501 attactttga ttactatcac atccaaccaa cattccagct gtcattgcta cagttaatat
     1561 aaatatcaat attcttttga aacgcattaa atttcactcc tcatacattt atgatatttt
     1621 tactcttatt tacttttaca tcctatttat aattttttta tatacaattt acaagtacat
     1681 tttgaaaatt ttttaataaa tattactata aaaaagtgtg caatagactc ttatctattt
     1741 acacacttcc ctacaaacta aatctaataa atcaacactt aattttatcc aaaataaatc
     1801 caatttagca tctcaatatt tagtattcta tcctaattta ataaaaaaat aaataatatt
     1861 acctcaaaat atatttattt attttttaaa catatgatac cagtgacacc aggaccagca
     1921 tgtgcaccta tacacacccc aatttggaaa aatctaattt ctttaggtct taattcatct
     1981 tccataacct tagataattg ttctttttcc ttaaaatcat cactatatcc tatatacaca
     2041 atttggtctg ataaatcatc cccacaattt gattttatca attccatcat cttagaaatt
     2101 acattctttt tccctcttac ttgagatatt tgcgaaacta gtccatctct tatttcaaga
     2161 atcggtttta tatttaatat acttcctatt gctgccttag tagatgatat tctacctccc
     2221 ttttgtaagt attccagtgt atctactgaa aatataacaa aagccttctc ttttaattca
     2281 tccaaaacag gcaatatttc atcaacagtc tttccttcac ttgcaagttc tcctgctttt
     2341 attacaagta aaccagttcc catacaaagc aagttagagt catatgtata tattttaccc
     2401 tctacatcat tttttgccat tacagcactt tgatacgtcc ctgtagctgt agcagaccct
     2461 gctatataaa gtatctctct accctcattt gtatattttt caaaaatttc cttaaattgg
     2521 gcataagtag cttgagaagt ttttggatat acattttctt ctctaagcct tttataaaat
     2581 tcatctccag atatatcaat tctatccttg tattcttttt cctccagtat aactgttaac
     2641 gaaactatat ctatatcata tttatctaac aaatcttttg gcacgtccga taaactgtca
     2701 cagattatct ttagattttt cattaagtat gctcctttct catttaggct tgttaaacta
     2761 cctcatattt gggtatccta tttgtcttaa agcctcgtac actacaatag caactgaatt
     2821 tgataaattt aatgacctag ctttttcaac atctaacata ggcactctaa tacaagtatc
     2881 catatttgct ttcaacaaag tctctggtaa tccctttgtt tctttcccaa atactataaa
     2941 acaattttct tcatatttca catctgaatg tgactgttta gcctttgttg tagaaaaaaa
     3001 gtatttactg tttggatact tttcttgtaa ttcttcaaag ctatcgtaat attgtatatc
     3061 agctatatcc caatagtcaa gcccacatct ttttaggtgt ttatcatcca atgaaaaacc
     3121 cagtggcttt actaaatgta aagttgaacc tgttgctgca caggttctta ttatatttcc
     3181 tgtattttga ggtatttctg gttctactaa cactatattt aatgacattt taatcctccc
     3241 taaatattgc ttctatttat caaattttat cttataaata gaataacaat aatattatac
     3301 tattatataa aataatgtta ataataattt ttatttcatg tatataatag ttttttatct
     3361 aacattttca caagtattat tatatcagaa aatgactctt gtacaactta ctttctaaaa
     3421 gttatttcgt ttcattaagt tctttataat aattacaatc ttcttttatt gggcaacttg
     3481 cacattctgg atttctagct ttacacattc ttcttccatg aaaaattaat acatgatgtg
     3541 agtgtgacca tctttctttt ggtatagctt ccatgagtgc aaattctgtt ttttgaggat
     3601 ttggctcatc cactattcct attctattgc taactctaaa tacatgagta tctactgcta
     3661 ttgctggatg attaaaagcg ttgctaagta caacccctgc cgtttttctt ccaacaccag
     3721 gtaattttat aagcttttct aagctatcag gcacttcacc atcatataat tcacatagct
     3781 gttcagatgt atcctttatt ttttgagatt tgcttttgta aagaccacaa ctctttattt
     3841 ccttactaat ttcttcaata ctcaaattag caaagtcttt agctgtattg tactttttga
     3901 acaactctga agtaacttta ttcactctta catcagtaca ttgtgctgat aaaatagttg
     3961 ctatcaaaag ttcaaaggcc gtcccataat ttaactcaca tttagcatct gggtacaact
     4021 tttctaactc atctaaaatc ttatttacat ctttttcatt tgctgactca tttttaattt
     4081 tagacttact tttaattcct ttacttagtt tttgcgtatc cttactagaa ctactattct
     4141 ttgttttttt gtcgtgttca ctttttttat ttatcttttc tttctcagtt acgtctttct
     4201 tatctatacc ttttttattt atctcttctt tatcaattac ctctttttta tttatctctt
     4261 ttagatttac atttttcata attatccccc tttaaaatac taatttataa aacgctattt
     4321 atacatagtt taatcatatc aacaaaaaat aaacatcaat atataaaaca tacaaaataa
     4381 gaatttaatt tatatagatt tcacaaaaaa agcaaaaact tattaaagtt cttgcttttt
     4441 attatacata aatacccatt aaattctata ataaacttat tcttttgaca cagtttgtat
     4501 cttactgaaa gatattaatt tttcttttac cagtttcctt atttcttcaa atttaacatc
     4561 tgtcaatatc tctatagcct cttctactct ttcaacagta tatatcttaa atttcccatc
     4621 ttgcactgca tcattaactt catctgataa aacgagattt ctttgatttt ttctaggaat
     4681 tatgacacct tgctcaccat ttaacccttt ggttttacat atagaataaa atccttctat
     4741 cttttcactt ataccaccaa ctacttgtat atcacccttt tgatttatag aacctgtaac
     4801 agcaatattt tgtttgattg gtactccact aagagatgat aatagtacat ataattctgc
     4861 agaagatgca ctatctccat ctattccacc ataattttgt tcaaaacaaa catatgcatt
     4921 tagtgacaat agcaaatcct gtgcaaaatt ctcagaaaga tagccgccta atataagcac
     4981 tcctttgtta tgtatagagc cactcatatt tacttctctt tctatattta ctataccttt
     5041 acttcctggg ctagtggtag ctgtaatcct tgaagctcta ccaaaagagt attctcctgt
     5101 acttaagact gacagaccat ttatcactcc tacttttctt ccctctgttt ctattagagt
     5161 aaatccattt tcaattgatt catccatatg tgtttccact ctattgattc tttttctctt
     5221 ttcacttatt gcttttttaa catcacactg ctctgtatac tctgaatttc taaattctgc
     5281 ataagcactt ccttcgatta caacttccat tattttatta aacttagttg atagtttttc
     5341 taaatcaccg gacaatctag tgctaaattt aacaacctct tcaactgccg atttagtaaa
     5401 atgtcttaag ttattcttat cacattggga tgctataaat cttgctattc cctcttcatt
     5461 accttcattt ttatccattt cactatcaaa atctacaaat actttaaaat atttttcaaa
     5521 atcttcatca tatctatata aaatatcata tatatagtga cttccaatca gtactaactt
     5581 aacatctaat ggcatatttt ctggtttaat tgctgtttgt gtttccaata ttactttttt
     5641 agtctgcaaa gtctttttaa gaatttccca agacattgta tattttagta attggtctgc
     5701 ataaagtact aaataaccac cattagccct atgaaatgct cctgataata gttttgtgaa
     5761 atcagtcttt atatttccat ttgcataatc atactctgcc tttccaaata gatttgctgg
     5821 acttgggttt atctctacta caacaggtgc tgattcttta ttttttgaac ttccgttgtc
     5881 tacaaataag ttaattttat atttaataaa atgctcttta tcatacttat cttttaactc
     5941 ttcttcatct aaatagaaca aatacatata ttctattata tctttcttta tattttccag
     6001 ataatcttga atcttatcat aattttcata tttttcacac aatctcttga tatgaggttc
     6061 tactacaagc ttagctatct cttcttcaag ctctaacact gctttttcag ctatttcttc
     6121 taagtttcta attttatata cgacctgtat cgccatattt tctagttctc tcttagcttt
     6181 gtaaaactct tcatcagact catcactttc atcttcctct tctttcaaag ggataaaaac
     6241 tattcccatt ttactctgtt ttaatttaaa tcctttttct tctccatatt tcttaatttg
     6301 cttcaaaagc atatcttttt ctatttcata ttcatccaaa agtttatttt tttctatttc
     6361 aaaattttca ctttcaaaag cattcttaaa atcttccaaa agactctcaa ttaatttctc
     6421 catatctttc ttaagttctc ttccaaaccc cttttctaac tcaactataa taggctctct
     6481 agggttttca aaattatata tatagcacca gtctttatgc gtattttttt tggatgcata
     6541 ttcatttaaa acctttagag cataagtact cttaccagtt ccagattcac cagctatata
     6601 tatgttgtat gctggattat ttatttttaa acctagctcc atagcttcta cagctctttc
     6661 ttgacccaat atacaatcta gtggatttat ttcagatgta ttattatatt tcaatattcc
     6721 cccacctccc catatttaac tttaatgata taatatgact ttcacacaac aagtgttaaa
     6781 gtaaatacac attaaagtat atgaaacaga ctcttattat tagtcattat acttatctaa
     6841 aattatttcc atatttctct ttattatatt tttccctctc cagctaaaag ccctatctcc
     6901 atatctcctt ttaaattctt tatttgaaat attttgtatc tcatcataat ccaaataatc
     6961 tattatattt tctttaaatt ccaaaatatg agttgttggt atttcaacat tatgtggaca
     7021 tacttcttga caaatatcgc atccaaatac ctttttgcca ctctttaaaa cagctttttc
     7081 ttcctgtgac aaatctcctt ttttttgagt tatatatgat aaacatttct taggattcat
     7141 atcataattt cccaatatag catttcccgg acaatatttt acacacttac cacatttaaa
     7201 acagcttttt tctagtggtt tatcttcttc aaacttataa ttatttacta tataccctat
     7261 aaatacgtaa gaaccatatt catcagttat gatattatta tttattccaa aatatcctat
     7321 tcctgataaa taagctaaat acctgtcaac taatggtcca ttatcagcaa atatcttata
     7381 tttaaaatct gttacttttt tagaaatata atcgcaaatt tgttgtaaaa atttctttac
     7441 tacaatatga taatcctttc catgacaata ttttgataaa tttgaatttt tatttttttc
     7501 ttgtctattt atataatatg gaaatgcaca cactattata gagttagcat cctccattat
     7561 atttcttgga ttaattctgt tttcaattat tggttcttcc ataccagtta aataaccttt
     7621 tttatacctg tctttaagta tattttctaa attatcatac ttatctacac ctgctactcc
     7681 tacacaattt aatcctatta aattacaaaa ttcttttaat tccctattat tcataaaatt
     7741 attccttttt aatctattta accttttaat ttatttaact tttttatata ctcgaccttt
     7801 ttacccattt aattttttta tctacttagt ttttttatat actcaacctt tttacccatt
     7861 taatttttta tctgcttagt attttttact tattcaacct ttttacttat ttaatttttt
     7921 tatctactta gtctttttta tttaacttac ttaacacttc tatcctactt agtctttttt
     7981 agatcttcaa ttttttaact acttaactct tttatctact tagccttttt tagctattta
     8041 atgtttttac tcacctagcc tttttaatct attcaatctt ttttacccac ttaacctttt
     8101 tggtttttaa tctaaattct aaaaattcaa atatcattag ttatattttg acattcttcc
     8161 tataattaat gtaagaagat tgattttttc ttatatttaa tattccattt acattactgt
     8221 ttattaagtc tttacttgac ttatattgtt ctcttttttt ctcttcacta aacttatgtt
     8281 cattaatatt gtgataagtt tataatagcc taatatgaat atattcagca tatatcagat
     8341 tttaaaattt gtaaataaaa cacttgtctt atatcactac atccaaagtg gaaaagttca
     8401 caaataagct ctgtaaaaac actttaaata acaatttgct tttaaaccat atacagatta
     8461 taataaatac tgtataagga tggtgaaaaa tttgattaaa ataacaattc caggtagacc
     8521 tattagtaaa tctaatttta aacttcacaa cataaatggt caagcatgga tgccttcaaa
     8581 gggaaaatat tctaagtatc ttgcatacga aaacatgatt gcaggtttta taaaccaaca
     8641 gtatcaagga gaaactgttg aagaaaatct aataacagtc ttgaaattat tcttcccaaa
     8701 taagagaatg ggggatttac ataattatcc aaaaagtatt tgtgatggta ttgaaaaaag
     8761 tggaataata aaaaatgata aacaactcaa gccagtactt ttatttgatt ttatagataa
     8821 agataaccct agggttgaaa ttgaacttta tccagtatct aaatataata tatcctacaa
     8881 tatttttgaa aaataaagat tttgtatgtt attcgccatt atattgatgc tctagtattt
     8941 gaaactatac taatacaaca aataatattt gtgttatatc tatactcacg caaatattta
     9001 ataagtatta aacaaatatt aaatttatat aatgcctata actatgtaaa tttaatattt
     9061 gtatataaga ccacatataa taaaaagaaa tcggagtaaa tttactacac cgatttcaat
     9121 aaacaaaatc tatcctagtt tttcgacaac agtcttcagc atttctctta taggaagttc
     9181 atatggacat cggctctcac aaagcccaca gtcaatacac tcagtaggtt taacatccat
     9241 aacctcatat ttttctttag cccactcttt taatccatat ctagtataat aaccttcaca
     9301 taaaaaactc aatggtatat ttattcctac agcacaaggc atacaatatt cacatcttct
     9361 acagaatttt ttacctaaag aatttcttat ttcttcaatt tccttattat ctttttcatc
     9421 tagcacaaga ttttcaagta cggccacatt ttgtctaacc tgttcaacac tctccatacc
     9481 tggtataact acatctatgt aatctttaga tagtatatat ttaatagcca atgttgcatt
     9541 atctaaagca cctccagcta aaggcttcat tactattatc ccaattcctt tttcatgagc
     9601 ttttttaaac acatcatctg cttgtccttc aactatattg taagggaatt gtatagtgtc
     9661 aaattttcca tcttctatag ctttttctat agtatttaaa ttgtgactag ttataccaat
     9721 atgttttatc ttaccttgct cttttgcctc taaaagggca ctataagcca ttttatcttt
     9781 aaaaagatta tcatattcct cttctttaac attatgaaat tgatataaat ctataaaatc
     9841 agttttaaaa ttatttaaac ttatttcaac atctctcttc attgaatcat aatctctaga
     9901 catactttta gtagctaaga aaaatttatc tctttttcct tcaatggcaa ttccgattgc
     9961 ttcctcactt atcgtatacc ctcttgcact gtcaataaag tttattcctt gcttttctaa
    10021 ctcatttata actaagttgg tatcatcttg agtaatcctt tgtattggaa tacctccaaa
    10081 accaactctc tttattttca tattagtatt gcctaaattt ctcatatctt tccccaccta
    10141 acttttaata attttttata taatataaat atgtcacctt taattataca acaaattatg
    10201 agaatctttg caatatattt acatactatt cataatatag ttatatttta tatcagtcta
    10261 ttcataatat catcatactt tatacccagt taattcgtat acaattttcg ttattcctat
    10321 ctattaattt aaattattac atttcatgat tgtatctcca ccctaattat gttaagagtg
    10381 gagtatttta catgtttaaa taaaatttta tttactagat aatatttctt ttatcatttt
    10441 aagctctctc ttatgacctt catcatcaaa aggagtttct aagaaaaatg gtaaatgttt
    10501 taaactagga tgttccataa aatcaattaa tgcttttaat cctatctttc cttcccctat
    10561 aggagcatgt ctgtcttttt tatctccaaa gggcatcata ctatcattta gatgaacagt
    10621 tttcaacctg tctataccta taaccttatc aaactcttcc aaaaccccat ctaaatcatt
    10681 cactatatca taaccagctg aaaaaatatg acatgtatca aggcacacac ctattttttc
    10741 tttgtgttcg attttatcta ttatactttt taattgctca aatttaaaac ctatttcagt
    10801 tccctttcct gacatggttt caagaagtat agttatattt tcatcgccct ttatagcatt
    10861 gttcaatcct tttactattc tatctatacc aaaatctaca ccaccaccta catgacttcc
    10921 aggatgaaag cacatgtatt caattcctaa tgaatccatc cttcttatat cctcatctat
    10981 cacccttgtt gcaaattcgt atacatcatc ctttgtgcca cccaagttca tagtatatgg
    11041 tgcatgtgca agcagtggtg caaaattatt tgcttttcta atttcttgaa atttaattat
    11101 atctttttca ttaaactctt tagcatttcc tcctcgtgga tttctactaa aaaattgaaa
    11161 tgtatttgca ccaatatata cagctgtctc agctgcatta gcaaatcctt ttgctattga
    11221 aagatgtgtt cctaatttaa tcatattaat ctccttttat ttgtactaca acttgtactc
    11281 aattttaatt ttgaactact ccaccttagc tactttcagc caacatctaa agatgaagat
    11341 tcctatagta cttttacact aaaaatttat aggctctaag ggatgttcca tccccactaa
    11401 tttcattcct cttttaatat atttctacca ttgatttaat ttatattaat ttttaatttt
    11461 aatatttaca ttttaattat acccattcta atcaatttca aatattataa tcttacaaac
    11521 tttgtataca ttatctaagc acttcttaga tagtgaatac atcttacaca ctatctatca
    11581 tttacaaaca caatagtata aagagacaaa aaaatagaga ttaaaaatca ttactttacc
    11641 ataccaaaaa ctattttttg attattaagt aaattttgat gttcaatctc taatcttata
    11701 tctttaatta agccataatt aattctttaa ctaggacatt cctcctcaag agtaggaact
    11761 ataaccatag ctatatcata cttagaacct tcaacattgt gttgtctttt atttaaaatt
    11821 tcatctatct ttgacttcat agtgtcacta agttcaacta attcatcatg agtaagagaa
    11881 atatcatgat aatcaactat attttcattt tctaaaacat cttcctctgc tgccttataa
    11941 aaaacttcac tcatattttc aaattttgat atgtacaatt cttctttttc ttccccattg
    12001 tctaaagaaa aattaagtat cctattccct ataaccacat tttttgcact tggataatag
    12061 tacttttcca caatccccga ctttattttt tcctcaacta attctaaaat accaactttg
    12121 tataacattt ttatatggta gtttattttt gcatgaggtt cttccaataa ttgagataat
    12181 tgttttgctg acaatggcga tttgtcaaat gcttttagaa tatctattct acgtggatgc
    12241 gcaatagcct ttatgcactc caaatctcgt aataccaata cctctttcat tgacccctcc
    12301 taaaaaattt atttaattca tatttcttta caatttaatt atatattaaa ttatatgttg
    12361 ttgtcaaaaa aatcctttct taatatttta aaaaatattt aatttgagtt tatttgacaa
    12421 ctcctctaaa actttaactc ctgcgacgct gttacctttt ttgtcaagcg caggtccata
    12481 aacaccaatc cccatgcgtc ccggcacaga agccattata ccacccccaa ctccagattt
    12541 tgcaggaatg ccaactttaa tagcaaattc cccagaagca tcatacattc cacaagtcat
    12601 cataaatgtc ttgacaattc tagaaaccat ttcactcatt aaatgctcgc cattttctat
    12661 atccactcca taatttgcaa gatttattcc aattctcgct aaatctacag aatctatctc
    12721 aattgagcat tgtttaaaat aaaggtctag aacatcttct acattacctc tgataaatcc
    12781 atcacttttc aataagtaag ccatagctct gtttctatct ccagtcattt tttcagactt
    12841 atagacatca tagtttattc ctatattatc attttttgct aactttctaa agaaactaag
    12901 cattctttct tctttttctt ctaaacaact cccatttata agggaagtag ttactatagc
    12961 ccctgcattt atcattggat tacagggttt ttttgtgtca ttaatttcaa gtttcattat
    13021 tgaattaaat gggtctccac ttggttccat tccaacgttt gaaaaaacgt cttcccaatc
    13081 attgtccata agtgccatag caagcacaat tggttttgaa atactttgta tagtaaactt
    13141 tgtgctacag tttccagcac tataaagatt attttcgcta tctatgatac aaattcctaa
    13201 atcatttctt ctagcgtttt ttaattctgg tatgtaacta gcaacttgtc cataattagt
    13261 atacttctta ttagaactta taatttcttt taataatgtc tcatctaacg tattcatatg
    13321 cacctcttat attatgttat atattctatt ttagcacaag tttgtactat aataaaacag
    13381 tgttaaaaaa aattatactt taaagttatt ttctacaaga atcaattcat ttttcaaaca
    13441 atttaaatag tttaaatggc ttaataattc agtaatctag taattcaata atttagtaat
    13501 ttaacaacct agtaatttag caattcagta atctaataat ccaataattt aaatttttat
    13561 aacaccaaaa ttttctaact caatatcttt tactctttta ctcttttact cttttactct
    13621 tttactcttt tactctttta ctcttttact cttttactct tttactcttt tactctttta
    13681 ctcttttact cttttaaaaa attatcacac aaattaacaa aatattaaac aaagaagtaa
    13741 actttaaaat aaaaagcttg cttcatacaa aagtataaaa caagcctttt tatatatcaa
    13801 ctcaaacttt aaaatctgta tcaatttaat tttccattta atatacttca cataaaccaa
    13861 tcgcactatt tactatgcca tttaatcttc ataaaataat ctataataca catattaatc
    13921 aactatttta cttcctccaa taaattccct aagaattgaa atacctggta tatcagaagt
    13981 gtcgtccaat tcaacaaaat actgcaaaaa ctttagtaat ctagtagctt caatatgtgc
    14041 aggattatct tcctttatat cttccaacaa aggtttcgca aatcgtttta aaactgccaa
    14101 ttcatataca caagcagagt taaatatagc atctgcctct tcttggtatg ggaatatatt
    14161 cttcttttct cctcttctaa ctgatgccca ttgtaaaata gtattatcag cactatatcc
    14221 tctaaaatta tagtctctaa caattcttct tatcattctc aaatcagcag tagggattcg
    14281 attatggtca tccaaattta tttgagtaag ggcacttatg tatatcttaa atttatcttc
    14341 atctggtata gatgatgtta aaataggatt tagcccatgt ataccttcta atataattgg
    14401 ctgatttgaa tctatcttta tttttttacc agtatactct ctcttgcctt ctttaaaatt
    14461 gaatcttata tcatcaattt cttcaccagc taaaagtttc tttaagtcta agttaaactt
    14521 ctctaaatct attgcataaa ttgattcaaa atcataattt ccatattcat ctaaaggggt
    14581 atgttttcta tctataaaat aatcatctaa agaaatcgaa atagggttta aattattcac
    14641 tctaagatgt attgataatc tgtgagcaaa acttgttttt ccagatgaag atggagctgc
    14701 tattaaaatt actctcttat tgttatcctt tatcatatct gctatttgag ataacttctt
    14761 ttcatgcaat gcttcaaatg ttcttattat atctccatat tcattgtttt ctattatctt
    14821 attaagagat actaccttgt caattcccat aagtcttgac cattcttctg cttcataata
    14881 tacacttgat agcttaggtt gaggtacaaa tttcatagga agagtcttat cttcttcact
    14941 aggacctaaa attataacac ctccattata aagcttaata tcaaatgatt ttatataacc
    15001 agttgatggc aacatataac cataaaaatg gtctatatag tttctacact tatatacttt
    15061 agcactatca tactctttgt atttcaaaag ctctgccttt tcatacattt cattattttc
    15121 aaagatagaa atagcttcat ttcttgtaac ttcaattttt tctataacat aatcgttgtt
    15181 tactatctct ttcatcttgt tttttatatt ttcaacatcc acttctttaa gctttctatc
    15241 tatatgaact tcacaatata gcccatctga taacgaatgt tctattgtaa ctctactatc
    15301 ccaaaagatt tctctacaag ccattacaaa tataaacgac atgactctaa agtaaactct
    15361 ctctccatct tcattagtag tatctaaaaa atttatctca caatccttct taactctaca
    15421 atttagctct tttagtttat tgtctacaac tgcaagtgtt atataaccct tatgctcatc
    15481 acaaaattct ttggctatat ctcccaatct gataccatgg gaattttctt ctaatgaata
    15541 ttccttatct tttccttcta tttttaagtt tatttttttc acttcaacat ctccttcctt
    15601 ttgatgaata taaattttaa ttaatgaggc atatcaacaa gataaagaga ggtatttaac
    15661 cctctcctac aatattatcc aatttactta tagtatcttc aatatcttcg taatttattt
    15721 ctaatactaa atattctgca tctagtgtta agacctcttt aatcccctct tcagataaaa
    15781 ttcctcttcc tataccaaca tgtgtatcat tgataccatc attatcactt aagtgtatca
    15841 gccttatttt atcctttaag ttctttacat aatcatcctc atcaattaaa cagtgtccag
    15901 tatcgtaaca aaaacaaatc ttagaatttt taatcctctt aaatatatat tcaaaatcat
    15961 aagatatatt tccaatattt gaaaaatccc caccttttga ataagtattc tctatacata
    16021 catatgaatt tgtatttagt ttgtctaaaa aatccacact attttctaaa tatttgtctc
    16081 tattccttct aactctattt gtcataacat atcccaaatg aaggttaaaa taccttatat
    16141 caaatcctct tagttcaaat tctatcttct caataaaatt tatccatgaa tttcgtatat
    16201 actctatgtt ttcgcaagta tttaactcca taggcaagtg tatccctata gataatccta
    16261 acttagaaat tctctcttta tatttacata gatcactaca ttcagatata ttgtcaattc
    16321 caatctctaa atgagttatt tgctttatac tctcacaaat gtttaaagcc tcctcaatat
    16381 taaacaataa ggatgctata ccaactgcca tacaaatcac ctactcaaaa atacctatat
    16441 ctgtaaaagg aaatactctt aaaataactt ttcctttaat attttcttca tctactaatc
    16501 ccacttcttt atatctactg tctaaactaa cttctctatt atctcccatt gcaaatactt
    16561 ttcccttagg aatcaccata tcaatatcgc cttcagtata attatcatgt atatatgaaa
    16621 cttcatttaa taacttacca tttatataaa ccttagaatc cttaattttt agatggtcac
    16681 caggaacacc tataaccctt tttacaagct cttttttcct tccattctct tgtaataaat
    16741 cagtcttaaa tatcattata tctccacatt ttggttctga taacttatat gtcatcctgt
    16801 ttgctaccaa ataatcatgt gatttaagtg ttgggtacat tgattctcca tttactagtg
    16861 ttggttttat aaaacgagtt ataataaatg ccaaaaaaag tgcagtaata attattttta
    16921 tccactctac aatctcttct ttaatagttt cattcattca caaattctcc tttatagtta
    16981 tattatcttt attaataatg tctcttaaac actatctttt agataagtct actaaataag
    17041 gtgttgtctt ttttatatag acaactattg tgtatggtct ggtgatatca gttaatcagc
    17101 gattgctcca aattttatat gtttagtcaa tagtccctat cttagaaaat ggatacaatc
    17161 tgactagaac ctttcctaaa atggcatgct cgtcgaccaa tccaacctca tcgtatctac
    17221 tatctaaact tttttctcta ttatctccca ttgcaaataa ttttccttct ggaactacga
    17281 tatcaacatc tccatcagta cgattattat gtatatagga agtttcatct aacaatttat
    17341 catttacata taccttggag tcttgtattt ttacatggtc accaggaacc ccgataactc
    17401 tttttactaa atcttttttc tttccatttt cctctgttaa gtcggttttg aatactatta
    17461 tatctttgta ttttggctct cctaccttgt acgcaattct attaactatc aaataatcac
    17521 gttcaaccaa tgtaggatac attgattctc ctttgactat tgttggcact ataaaacgag
    17581 ttattgcaaa tgccaaaaca agagctatga caatcacttt tatccattct acaacttctt
    17641 ttttaactgc ttcacccact aaaatcgtct cctctgtatt aaatattaag tcaatctaca
    17701 gcaaaataat ctactataaa cctacaatat aaatattata cttctttttt ctactagttt
    17761 aaaatacttt tctaagacct ttaggataat gattcttaat tacaccagaa gtttcttttc
    17821 cccaacctaa aggtatgcct tcaactgaaa ccaaaaccca tcctctacta tcattagaat
    17881 ttacaacatc cccttttaaa tatttaagaa ttgattcact ctgtacactg aagttttcaa
    17941 cattttttac atcttcaact tttaagtaat gagatagtgc atgagaaggc tcaaatctat
    18001 tcttctttaa aacccctaaa tgcaaaccgt atctcaatac ttttagtttt tttgtatctg
    18061 gatatatttt aggaagtagg tacaaatttt ctcttcttaa ataaaattta ttttttttat
    18121 tactataaaa atcaaccttt aaaaatttct tttcaaactc cctataatcc tttatttctt
    18181 tatctaaatt ttttattttt aattctttga cattacattc ttcttcttct aattttttta
    18241 ttttggcaac aaaatgccct tctcctttta tcttatgagg ccataatctt tccatttcaa
    18301 taagttctgc atgtggatat tcactgataa attcatttat aacatgctca ttttcttctc
    18361 ttgaaaaagt acaagttgag taaattaaaa taccatcctt ctttaacatt ttatatccat
    18421 ctcttataat ctctttttgg atggactgac actctactac ctttgcatga ctccaatctg
    18481 atatagcaac ctcgtccttc ctaaacatac cttgcccaga acaaggtgca tctataataa
    18541 ccttatcaaa atacccatta aacgtctttc ttaagctatt agaatcagtg tttgttataa
    18601 tacaatttct cgctccaaat cgctctagat tttcccctag agccttaatt ctactaacat
    18661 taatttcatt agaaaccaat aaacctgtat catttagctt agatagtata tatgtagatt
    18721 ttccaccagg agcagcacac atatcgagaa ctttttcacc ttctttaata tctgcctttg
    18781 gtattacact cattgcagaa ggctcttgca aatagtatgc tccagcctca tgcagtggat
    18841 ttctaccagg tctatcaatt ttatcatcat aataaaaacc ttcttctgcc catgatattt
    18901 gattcaaatc aaacagaccc aaatcaaata attttttctt gtcaattttt agagtattta
    18961 ttctaagccc agtagtctta ctttcttcat aactttttat aaaatcatca tattcatctt
    19021 ttagtatttc ttcaacatct tctaaaaatt cttttggtaa ctttgtcaaa tctataatcc
    19081 cccttcaatc tgctttactt gtgtgtcatt tattatactt taattattta tttctttctc
    19141 ttaaatttta tttcttcttc tttttcctaa gattaccgaa aaacactttt ttagagttat
    19201 tcatatattt ctcaagttta tcaagattta tcttccacaa aagtattaca taaactataa
    19261 gtaatataat agcccatcta tattctatca tcaatatgaa atcaaaaact ccatgtaata
    19321 aaattggaat taacactgcc ataaacaaat actcacgtct tttattttta tttccctcaa
    19381 atttatactt agaaatatag taacccatag taattgcaaa cattacatga gctggtatag
    19441 agatgactgc tctattaata ccaacttgca gtgctagatt tctactttca gaaaaaatat
    19501 aaaccatatt ttcaattgtt gcaaatccta aagctaaaaa tacagagtaa ataataccat
    19561 ctaacttttc agtaaaatgt ttttctttaa ttaaggcagg aatcagtatc agagctttta
    19621 ccccctcttc tacaagtcct gcaacaacaa atgatacata tattagttct gaataacctt
    19681 caaatacatt aaacttcatc agtaaatttt ctaaaagtat aattataaca cttagaaaag
    19741 caccgattaa aaaaaattta attagatgta ttagaggttc tctacaatat ctatctttag
    19801 accttatcca aaacattcct atcaatatag gaactattgc taataaaaat aaatctagct
    19861 tcatagatta ttttcctttc aaaaattttg atttatttat gacttatatc atctacttat
    19921 ttttaactta tttatgtttt aaatacacac taaaatatac attaaattat tttaaattat
    19981 ttaaatacaa atatactcaa aaaaatttaa atttatatct atattattta acaaatttca
    20041 agctatattc atatcttgaa atataaggga actaaattca tttaaagaaa gggtgatttg
    20101 atgcaagatg gtttcttaac agtaagcata attgatgcta ctaacaatag acctattcaa
    20161 aatgcagtag taaacatata ttcaatgtct aatggtagcc aaagctcatc aactttatac
    20221 caaaacctaa gaagtaatga atctggtcaa gtgactgggt tagtattacc agcaccagat
    20281 gtagattact ctctacaacc atctgatgtt agaccttaca gccagtatat agtggaagcc
    20341 atagcagatg gatatgagac agttgtcata gagggaacac agttattagc tacaattgaa
    20401 gcaagacaag gagttcccat gtctcctaga acaagaagta aacgttcttt ctcaagacaa
    20461 agtgagttga tttttgacat aggagaacat actttatatg gtacttatcc tcctaagatt
    20521 ccagaaagta acttaaaacc attaccacct cctactggtt tcgttgtatt agataaccct
    20581 gtagtgcctg aatttatagt agttcacgat ggtttaccag aagattcatc agctccaaac
    20641 tattggattc catttaaaga gtacattaaa aacatagcat catctgaaat atattcaact
    20701 tggcctgagc agacaatcta tgcaaatgta atagctataa tatcatttac tttaaataga
    20761 gtctttactg aatggtatag aaataaagga tacaacttta caataacttc aacaacaaca
    20821 tatgaccata aatttataaa taatagaaac ttatttgaac caattaacgt agtcgtagat
    20881 gctattttta atacctttat aaaaagacct cctacatcaa gacagccact attagcacaa
    20941 tattgtgatg gacaaaaatc ccaatgtcct gaccaaatga ctcaatgggg cagtaaagat
    21001 ttaggtgacc aaggatatga ctatgagagt atactaagat ttttctatgg agatgagata
    21061 gtgtttgaaa gagcacctat agtaagtggt gtaccagtat cattccctgg tactacacta
    21121 caagttggtt cttctgggca gtatgttaga actatacaaa atcagttaaa tgccatatct
    21181 aattcttatc cagctgtccc aaaagttata gaagatggta tctatggaac agatacagaa
    21241 aatgctgtta ggatattcca aggcatcttt ggtttacctc aaagcggagt agtagatttt
    21301 aaaacatggt atgaaatatc cagggtttat gtagctacaa ctagaatagc ttctttaaat
    21361 cctttaattt aaagcttgat ttagaatata aactcaaatt attaaataaa attattaact
    21421 taaaataaaa atggctgtta tgaactaaca tataccataa gtatttttac ttataagtat
    21481 tgtagtctta acagccattt tttagttata acttattttt ttagaacctt aaaactttaa
    21541 atgggggatt ttaagcttct taaaaacagt gcttagcaac tttaatttct ttaaaaatct
    21601 tatctttatt tttaaattta ataaaatgct attttaatga aaagcttact ttttacttag
    21661 agcctcaatt cttatttaaa atgctacttc tcatttagaa tattactcct tattatttaa
    21721 aacattattt ctcacttaga atattacttc ccatctaaat tattatttat tcattataaa
    21781 tataaacact attaatttaa aaagttattc ctaattttaa taataccatt tccttatcaa
    21841 tagacctaaa ccgcaacttt agacttatta gctaaagcca atattagacc taaagctata
    21901 gatgcaaatg cagaagcaat tactctatac tcagcaggga ataagaatac aattgtatga
    21961 catggtatcc agaaaaatgg tatagttttt aaaacactaa aaccaagata agcattccag
    22021 tccacaatat ttaccacatc tttaagtttt accttaatac cctttccaac ttcatatttt
    22081 ttatctataa aacaatccat aaccttatgg aataaaaata cagttggtga cattagtata
    22141 ttcatagttg cgctcttaaa tagagcattt gcaaaagcta ttccctcaaa tggaagcata
    22201 ccatccactt gtgcttgacc tacacctgat gagtaaattg acattccata tgtggtaact
    22261 atacctatta ttccccaaac tattgctcta taaaatactc ctactggtat tttccagtcc
    22321 ttatacaaaa ttctagcacc aagtaaatct cccattgtag ctaatacagc aaacttaaaa
    22381 aaacctccaa tatatggatg tgcacctgtt gcttccataa atacttctct actacttggt
    22441 attgctaaga cagcaataat gcaaataaga attccactcc atataaaatc gccttttttc
    22501 atattataaa tactatttaa tatataaata gttctccttt ctattaaaga tttatttaat
    22561 ttacaatcta tctacaatta tttattaatc actgattatt agatattcat tttccatgtt
    22621 taaatttatt ctagcccttt atctatttat tttcttactt tttttatcca ccactatcta
    22681 tatatttatt ttacgattac tctttcaccc taacccttta actatctatt tgttttttac
    22741 tactcttatc taccagtatc tatatatcta ctttacaagt actctttcac cctaactctt
    22801 taactatcta tttgtttttt actattctta tctatcagta tctatatatc tactttacaa
    22861 gtactctttc accctaactc tttaactatc tatttgtttt tttactattc ttatctacca
    22921 gtatctatat ctactttaca agtactcttt caccctaact ctttaactat ctatttgttt
    22981 tttactattc ttatctacca gtatctatat atctacttta caagtactct tttaacccaa
    23041 cctcctatac tttatatagt aatatgtttt taactttttt cattattctc aatatgtttt
    23101 ataactacaa atactctccc tccttaaaaa taagaataaa attaaccaac aaatttataa
    23161 tcatattatt actttatgta ttaagcaatt actatgccaa taaattttaa tttttttaaa
    23221 caactcttaa aaatgctaaa atgctaattt tctttaactt ttaatgaatc taatagataa
    23281 catttaattt ttgttatatt tttcagaatg tttcaattat tatttttaag ataaaaaaat
    23341 aatgttaaca tttcttaaca tacattaaaa aatgttaaca ttataaattg ggtttaatac
    23401 ttttactttg actcgattta cttttattct acttctttac tttattttaa cttagacttt
    23461 atttttttat cacttatttg agtcttattt attttattct cattctatat gttcaattaa
    23521 atttgtctaa gttctttgat atttttatta cataatttta acaagcttaa gtgttatttg
    23581 ggtagtgcaa ttgataatta tttaaataat catcaattgc atgtttgtat catcatagta
    23641 gcttcatgta tttaatcatg tttacttagg attttgaaat atcttagaga ttatatataa
    23701 cattagtcaa ttgctgcata attgtaagca attgaaattt gagacccatc ttcatttttt
    23761 atagtgatag gcttcataat ttttaatcct tcagttttta tcttttctaa atctttttcc
    23821 attttcttaa ttgtttcctc aagatctttt tgacttacat ctttaaccgc attagggtct
    23881 ttagcataat cttttaattc ttgaatatgt ttagcatatt cttcataagt ataatgctca
    23941 acaccatatt tttctaattc agtagggtca gttattcctg attttattag agattcaagt
    24001 ttaggtaaag caatattaga tgaatcattt ccatttgcaa atactgctcc agttcctcct
    24061 agtaccattg cagataccat cattgcactt ataagggatt tttttatttt cataaccaat
    24121 cttcctttct tatatattta tttggatagt gtagtttaaa acgactattg caatagttat
    24181 caaccacaca tttagactac cacaatagtc atatttatgt caagtatttc actaaaattt
    24241 tttaataaaa aatactacct caaaacaaac ttaattattt taagatagta ttttaattct
    24301 aattgctttg tgctattatg atttgcactt actttataga agttctgtat tgtatattat
    24361 taactgctaa caaatttcct tttcttgata taactaaaac accctcatta taattatttt
    24421 tctgaattga atattctgct gaaggagtat aaagtacatc ttcataatca ttagatttgc
    24481 ttgatttctc tacagatact tctgaataat tctcagtatt ccttacttta ttcatagata
    24541 tatcttcata acttttagat tcacttgatt tattcataga tacttttgac atactaacag
    24601 agatatttga atctactttt ggagtatata actcagttga gtcactactt attgaaagta
    24661 cacttttctc attttttgtt aaaccaaaag attcaacctc attaatctct ttattttctg
    24721 ttgcaaaaac aagacctatc ccacaaacta atacagttga aactaaaaaa gtaacataag
    24781 ttgatttttt aaatttcata atattaacta ttctcttttc tatttttgtc tttccaaacc
    24841 cactacatat tgtcattgaa aatggattat tctcctctgc taaacttatt agtgtagttg
    24901 cataatcagc cctatattcc tcaccaagta tactcataac cttttcatca caactaaatt
    24961 ctatgtcttt atttagtaaa aaaaacatca cccaaactaa gggattaaac caatgaacaa
    25021 caagagctac aagcataaac agcttcaaca gattatcaaa actattaata tgaaccattt
    25081 catgagttaa aacaaagtct aaagtttgat tattagcata attcatttgc ttcggcaaaa
    25141 taattcgtgg ttttaaaata ccagatgtaa gtggcgttct agtaaattca gatatacaaa
    25201 caataaatct tctaaaacgg ctattcttac acatccattt tttaatgaac tcgtgatttt
    25261 ttatatgaat tgaagtttta aaaagattaa ttattttaat atatctaaaa cataaaagta
    25321 tgctaaatat aatagtaact ataaaagaca aaatgcccaa catttccaac atcataatat
    25381 tttcaatact agacattatt tcaaatttgt cagaattgtt tttacctgta gagtcaccag
    25441 ctttcttaag agtataattt tccgttgatg cattccccaa ttctacatca aaagtcgatt
    25501 caattatact ataaatacta aaaccagaat ttaaacttac tggtattaga agtttaaata
    25561 aaacaatcaa ccacaataat acaaacacct ttttaggtaa ttttttaaat aaacatgctc
    25621 ttataaaaat aactattaaa agtaatactc cagaagtaaa actcatttct aacaatttaa
    25681 tgaacataaa tcttacctca ctttaatttt tcaacaatct gtttaagttt tgtaatctca
    25741 tcacttgaaa gattttcttt gttaataaaa gctgaaagaa atttttctga agaccctcca
    25801 aacattttat taattaaagt ttctgtttcc tgtttttgta cttcttcctt gcttattaaa
    25861 gctttacaaa caaaattcgg ctcaattctc tctattgcac cttttgacac caattttttt
    25921 ataaccgtat acgtagtgtt tctattccat cctgtttctt cttttaaaat ttttactaac
    25981 tctccagcct tgctttctcc tctctcccat agaacttcca ttactttaag ttctgaatca
    26041 aataatttta tctccatata aaatcgctcc tcaaatatag ttatcacaat agtcattact
    26101 ataataaaaa actatcatag tagtctatgc tatgtcaatc ctttattttt taataataaa
    26161 aactgccttt taaaaaattt cttataaaag acagttttat caatgttata ctttgatgtt
    26221 taatcaaagc catattttat ttgaatgtat aactatctat cttaatacat agtataagat
    26281 ttttctttat ctaatagtat atcctctacg tctgggtttt cttttactaa ttgtctataa
    26341 aagttacaat tagtaacacc tacatatgga attaaccata gtagacctat tccaagagta
    26401 gctattgaaa gtatatacca tcctataaaa ctaaagttta gtacaaataa tttaagtaca
    26461 tttcctttca tcatatctaa actagcactc attgatttaa atacgcccag attatccttg
    26521 ttttcacaaa ttaggaaagt agcttgagaa acatataata gcaatatata aactggtaac
    26581 ataagaacga gtattataag aactagagtt attccagtag aaataatagt tcctattcca
    26641 acattgtcac ttgataaata ttcaattgca ccactagtaa gtaaaactcc aaatgataaa
    26701 aatgctccta taattgtgat tataaaagaa taaatataaa caataattga ttcaaataaa
    26761 taaaaaccaa aacttcttaa ataaattctc ccatttacaa aaatatctcc catcttgact
    26821 ttttcatctt tagtaatttt caagaacata catgtgaatc ctgctgaaac acagaaagct
    26881 attacagcca ctacaatagt agtcaatggt tcaaaaggta atcctacaat tgatattaac
    26941 actatcaatg caatatatac tgccatagaa attgcacata taccccagtt tccagacaac
    27001 tgagctttag atactctttt taattcttgc cttgatacca taaaaaacac ccctttcatt
    27061 ttataaaaaa acttttaaaa atataaataa tcttttaaca tataatatta atatatcata
    27121 ttttcgacta tataacatac aattattcac catgttttat caagatatgt cataattgtg
    27181 ttactagttt tatatagtca atattaccaa gtacatcaaa taaatttgac taattatacg
    27241 acaaataata aaatacatta tactaatttt actttattta ataaacaaat tatccaataa
    27301 aatacattac ttaataaagt atattaatta gtaagataaa ttatttatta ttagtaaggt
    27361 aaattattta ctatttgtca agataaatta tttataaaat aaatcactta taaaatataa
    27421 tttatacttt gagaataaaa taaactatct tccaaacatt ttattatatg cttaaaagat
    27481 agttttgtgt ctttaaaata aattaaattg tatatattcc ttcacataac ttttgtatat
    27541 tactaggtgg ttgccattta ccatcttttt tagtatatgt aatcatagtt gtaacttcct
    27601 tagtcggctt cttattgtaa aggtctataa tcatttttgc catatcatct tgaacttctt
    27661 tttctttttt atcgtaattc ttttcatcag ttacataaga ttttactaaa ttgttcgctt
    27721 cactcattac tttactagta tctaaagctt tgcttacaac tttcaaagtt atcttatcct
    27781 tactagaaga ttccactgtt acagtctttt caacaccttg aattaactta acaattgttt
    27841 cgtatatctt ttcagcattt tctttaccat aaagaggtgt caactgagca atcattgaaa
    27901 ccttatcctt gctgttataa gtttgaatct gtttatattc agcttctgtt aatgcatcag
    27961 caattccttt ttcatcatac ttatacattt ctaatgcagc taaattagct tcaaaatttg
    28021 actttacttt ttcttctgca ttagaacacc ctatagttag aactaaaacg agagccataa
    28081 tagaagataa tattaacttt tttaccattt tcatacaaat atcctccctc aattaaaata
    28141 ataaaaaatt tatttatcaa cattataaca taaatttatc taactataga attattttga
    28201 atattttacc atttccagtc cattccgata ccgttttctt ttgctttgtc gtatattctt
    28261 tttgctgtta cgacgtcttg tacacctatt ccgacagttt taaacacaat tatctcatca
    28321 tcatcttctc tgccaggaat agttccattt ataacatttc ctaaatcacc actaaaatca
    28381 tctttactta tcttcccttc ttttaatgga atcaatatat ctcctgactc agataaaact
    28441 gcatctgttg attcaaaaaa tatcttagat gctctagtta aacaaattgg acacaactcc
    28501 tgcatgtctg gcatatatga gcctactgca cttattaaag ctcctttttt tactaagttt
    28561 ccattaaata ctggttgttt tgatggagta gctaaaacta ttacatctgc attatctatg
    28621 gcttcatcag atgattcaac tgcaactatt ttagtattat atttacttaa ttttaaattc
    28681 atttcttcta caaatttttc tctattttcc ttgtttctac taaaaactct tacctcatcc
    28741 aaatttctag cttctatcat agcttcaagt tgaggctcac cttgtcctcc aacacctatc
    28801 aaagctccaa tcttagaatc ttttttagcc aaaacatcta tggctgctcc agatgctgct
    28861 ccggtacgaa tttgagttac ataagtacca tccaatactg cacttacttc tccagtttca
    28921 ccatctaata gtagtactgt tgctggaatt actggcttgc ctttttgagc atttttagga
    28981 aatacagata caatttttat tcccccacac cctaattctt ctacataccc tggcatgaat
    29041 aacatactag catcttgact tggaactggt atattggttc tcaagggatt tacactcttt
    29101 ccttcacaat aaattctaaa agcttcctta tcagcttcaa ttgcatctct cattgtaaat
    29161 acttttttta tgtcgtcttt ttttaaaagt agcattttta taccccccaa ttttaataag
    29221 tctctatgtt aaatattata gcataacatt taatttaatc ttctatttca aatcaaataa
    29281 atctacatat tctggtttta gcatagagct tatcagtttt ttatttattg aaaattctgg
    29341 aatccctgct gcatatggag ttatatcata taaatcaaaa tatataacta gattatcatc
    29401 ttgcaaataa aagttttgat tctcttttat acctttaaaa ttatatattc cgatattttc
    29461 ttcatccttt ttttcaagtt cagctatttg tcttttaatt tcttcatcta taacttcttt
    29521 atatttagta ttatccttaa ataagtccat taattctaaa aattttccag ttctcatatc
    29581 cacattatat gctgtatctt gataaaatcc atgtgctcca ccactataag tataatatct
    29641 cacttttata ctaagagcag aatcagtatt ctttttaagt tcaaaatcta catttgcaac
    29701 aaacttattt ttctcatcag gattatcctt aagatactgc tttgcttctt tatatgattt
    29761 attataaaat tcaaatatgt cattttttat cttatcattt gtagaccttt caacaatctt
    29821 atttgaattt gttattacag gcatgtttat agtactttct aaatactcat catttttcac
    29881 tattgtttta cttcctattg tacttactga taaagtttgt ttactatttg tattaccctt
    29941 tggtaatgac tgattactca taacgctcac tgcttcctta ttatttaaat taattgaagc
    30001 atttttcaaa ttattatatt tatagtcatg tttaattgcc aaaacagcca ttatagtcaa
    30061 ggttaaaaca aatacatatc ttaaaacttt agcttttgta tccactttaa aaaatttcat
    30121 attatcattt tcctcctaaa tataaatctc tcttattata tttggagttt ctagggtttt
    30181 ttatccatat aatttaataa aagattaatt tttatttata aaaaattaat ctttttgttt
    30241 taaaatatta atatgtctta tcaaacagtt tgaaatttca ccaagaggta attgtaacat
    30301 aacagaaccc ctatcaaaag ctaccattgg cattccatat actatacaag aattttcatc
    30361 ctgtccaatt gtaaatgaac cattttcttt catttttaaa agtccatttg ctccatcata
    30421 acccatacct gtaagtatta ttcctatcga atttttacct gctacttctg ctactgaatc
    30481 aaacaataca tctactgatg gacagtgacc acttattctt tctccttttt cacaagttac
    30541 ataatatcct tgtttatccg cacacaattt catctggcaa cccccaggtg caattaatac
    30601 atttccttgt tcgactctat cattattctt agcttctctt acattcataa tacactgctt
    30661 gtcaagccgt tgtgcataca tataagtaaa tatagctggc atatgttgaa ctacaacaat
    30721 ccctggtgtt gattttggta agtcttttat aatttcaagt attgcttctg taccacctac
    30781 agatgcgcct atagcaataa ccatattatt aaaacgtccc acattaccgc ctccacaaaa
    30841 tcatatatca aaactagcat tttatctttt atatatagca ggttttacat atttatattt
    30901 agtattactt ctgttaatta cctctgcatg tcctacaaac aaaaaactat cttttttggt
    30961 agcattataa aatttattta taagttcttc tcttgttttt aaatcaaaat aaatcataac
    31021 atttctacaa aaaatcaaat caaaatgttg atatgaaaaa tcattcatta aattaaatgg
    31081 cttgaaaatt acactttttc taatcttatc acaaatttta aatgtaccat ccttattgtc
    31141 tataaaatac ttcttcttcc ataactcagg aacattgtta acatttgatt ctatgtatat
    31201 acctctttta gctttttcaa gtgagttagt tgaaatatct gtggctatga ttttaatgtt
    31261 ccacaactct ttattatatc caaaataatc atccaaagtc atagctattg aatacgcttc
    31321 ttctccactg gaacagcctg cactccatat atttatgttt cttattttat tattttcttc
    31381 ccagaaagga aatatactat tctgtataaa ctcaaagtgt tgaggttctc tcataaaaaa
    31441 tgtatgattg gtgctcaatc tatttattag gtttatagct tcatttcctg tcttatcttt
    31501 aaataataga ttcatatatt gactaaaaga actaagtttt ctctctatca ttgtattgta
    31561 taagcgacct tcaattaacg ctcttttttt gcttaaatca ataccatatt ctttttttac
    31621 atggtttaca agaactataa attcttcatc tgtgagtttt atcatgcaaa aacttcctcc
    31681 tgctaattta tcaaaactaa ctatatgcta ttaatcaaaa actttcgaat atctaaaatt
    31741 aatatagaat tatcttcaac tttcgcaatt tcttttatat ctttattaat attaatattg
    31801 ttagaattag ttgtagctag caaatttaga ttttctatag gaataacatc aataactcta
    31861 tctacaataa ttccaacttg atactcatca acctttgtaa ttattataca agttctctca
    31921 ttataatcag cttcaggaag attatacttt atatgcatat taataactgg tattattctt
    31981 cctcgcaaat taataactcc acttatatat gttggaagac atggtacata cgttattgat
    32041 tgaaatctta tggtctcaat cacattttct aattctattc cataaataac atcattgaca
    32101 taaaatgtta atacttgttt aataatttca tctttagcca tactttaaat cccctaatat
    32161 atttctataa tgctatctgc atctataatt aagcttatac ttccatcccc aagtattgtg
    32221 caacctgata aacccttatt ttttatattg aatcggttaa agtaaactgg aaatggtttc
    32281 acaacaactt gttgattacc tattatttca tcaacaaaaa tgcatactgc tttattctca
    32341 ttttcaataa ttatcatatt accatgcatc agattggtta cttttgtttg aatattatat
    32401 attttatgta atcttataat aggaatacat gctccatata ttgtaattaa ctctgtttta
    32461 ttttcttctg taattatttg atttaagtct gtaagtttaa atgttctcct tatagatgat
    32521 attggtaaag taaatagtga atctccaact ttaaacttca taccctctac tatagaaaga
    32581 gttagtggta tttttatagt aaaagttgtc ccttcatctg gtttactttt tacttcaatt
    32641 gaacctccaa ccttttcaat acttttacga acaatgtcca tacccactcc tctaccagaa
    32701 aattcagtta tagattcttt tgtagaaaaa cctggagtca taatcaaaga attgacctcc
    32761 tcatcagtat actcattggt ttgatgttta aggagacctt gttccttagc ttttgctaaa
    32821 atcttgtctt tcataatgcc tctaccatca tctgaaatac ttatcacagc ttctccacct
    32881 aaattttcag cagataaaac tatctttccc acttcttttt tgcctttagc tatacgttct
    32941 tcgataggct ctatcgcatg gtccatagca tttcttataa ggtgcataaa aggttctgtt
    33001 aaattatcaa ttacactctt atctacctct gtctctgctc ctatagttat taactctaca
    33061 tttttatcta attttttatt catgtctcgt acaattctat gcattttttg aaatacacca
    33121 gcaatttgaa tcatacgcat agacattact atatcttgca attcatctgt aagcttgtgt
    33181 aattgtcttg ttgacttatt gaaattatct atatcaacac ctgtagaatt tacactattt
    33241 acaaccattg attccataat tacaatttct ccaactatat tttgaagtaa gtccaatttt
    33301 tctaaattta cactcataat actctgctta cttattggta aatgttcatt ttctccactt
    33361 agaccatctt tttctatatc agttttttca tttaaaacat cttcttgtaa ctcatcttct
    33421 gtatagttat ttttataact tttacttact ttgttactat cttttaattt gttttctact
    33481 tcattattgt ttgatgtact tttcatttct atttcttttt tactaatatt tatatattct
    33541 tttacataga gattctcttc tatgatttta taaactattg aattatcctc tttagcaaca
    33601 aattgtatat aaaacccata atttttaata tattctgtag actctgcatt tgtttctaca
    33661 tcttttggat aaaaatctag aaattcacag taatctctaa gttcaaatac aagcatgaaa
    33721 gctctcacat tttccatcat gcaaccttgt tcaaagatta tttttactac atcagaacct
    33781 tctctgtatg caaaatttaa gtctattact tctatttcat ctgtactttc taaacttgca
    33841 ttatcctttg atttcataga acttgataat tccaaagtac tcacataatc ttcaattcct
    33901 tcgataaaat tagagtaatc agaagatata caacctcttg attgtaactc atctatatct
    33961 cttcttataa aatctaaaga ttgaaaaact aaatcaaata ataggtcatt gtctaaaact
    34021 tctattttac cttcacgtat agcataaaac aagtcttcta cactatgtgc taaagcagat
    34081 atattgtcta accccatcat agatgctgaa ccttttatcg tatgcattat tctaaaagtt
    34141 tcattaatat tgttatgagt aaatactttc tctttttcta tttgaatcat aatttcatct
    34201 aattgttcga gtaatagact tgtctcaaat ataaacatat ctaacatttg tctcatactc
    34261 ggttcaatat aattcacatt tatcacctac gacctacaaa taattttcta ttatatatgc
    34321 atctcataat ttaaatcctt gatgattcta ttatttcact atatatgtac ctcataattt
    34381 aaatatacaa taactctctt atttcgttat atatgcacct cataatttaa acccatgatg
    34441 attctcttac ttccctttcc tttagatgaa atttttctac taattctttt aaaatttgcg
    34501 cttgagcaga catctcttct gaggctgctg cactttcctc tgctgttgct gagttcattt
    34561 ggactactat ggaaatttgc tctattccag ataaaatctg tgtaattgct acttcttgac
    34621 tatgtacagc tgaagaaata ccattaatat aatcagtagt tttttctaca ccatttacta
    34681 ccaactccaa tgcatttgca gtctctttag caattttgac accattttct actgttttaa
    34741 tagcttcttc tatgagaata gctgtatttt gagctgcttt tgcacttttt ccagccaaag
    34801 acctaacttc atctgctaca actgcaaatc ccctaccata ttgacctgct cttgctgctt
    34861 caacagctgc atttaatgca agaatattag tttgaaatgc tatctcatct attgttttaa
    34921 ttatttttga tatttcactc gatttttcac ttatttcacc cattgatgtc atcatatcat
    34981 ccatacatct acttccaaaa tcaacttgtg atgcagattg gtcagatacc tcacatgcaa
    35041 gactagcact atctgcacac ttcttaattc catctgatat ttcattaatt gtggaagcca
    35101 attcttctac tgaactagct tgttcagtag caccctgtga aagagcttgt gcacctgctg
    35161 caacctgttc tgatgcactt gcaacttgct ctgctgataa atttatttca gaaaaatcac
    35221 cattaaaaga gtttattata ctttctaaag atatttttat tgatttaaaa tcacctataa
    35281 attcttggtc tatttctact cttaaatctc cttttgcaat actagttaat gtactgtcta
    35341 taaggtctat ataatttaaa agcatacttt gcatcttttt gacagaactc actaacagcc
    35401 ctatttcaga tttactttct tcaacgtcta tacttgttct taaatcccca gatgcaattc
    35461 ttgaaaagtg tttttctact ttattaatag gaataactat ttttaatttt attactgtat
    35521 attctattat tgtcagtatt attaagagag aaagtataaa tattgttctt aatattagac
    35581 tttgtaattc tttttttact tctacaattt tggcatttga acgggcaact atatcctctt
    35641 gaaattcatt tattaaagaa tccattttct cttgggagtt tatataatca ctactaaaaa
    35701 ttatattttg agctttactc ttatcattac tttcgactgc ctttattgca ctttgttctg
    35761 ttggtaccaa agaatctgat atttcttttg cttctaagat tttatttgac tcgctctttg
    35821 taagaccaat tttctctaat ttgttcaaag ctgattctct tgtttttccg tacaattctt
    35881 tttcataaat atctttattc tttttttctc ctgtaaatac atatcttctt aatacatcac
    35941 ttatctctct agttgtatct tttatatact gactttgagt tctcaaatta ttcatatcat
    36001 taatactttt ttctactttt tcaaatgctt tataagatga aatagaagaa aaaatccctg
    36061 ctagaacagc caatactata ataaccagca atacaattgc taatttagaa agctttactt
    36121 ctcttttcat atctgtactc ctttacaaag taagtttata tcttttttaa tcctttcatt
    36181 gtactcacta cgctacaatc ttttcctaag tttttaccct catacattac tttatctgct
    36241 aaggatatat tttcttctaa tgatatattt gagtttactt ctactactcc taatgtaata
    36301 gtgcacttta ttttattttc tttatagttg aaatcaaact cctttatttc tttacggatt
    36361 ctttctgaaa gtatcttagc gtcttctatt ggagtatttg tgagcattat caaaaactct
    36421 tctccacccc atcttgatac agtgtcaatt tgtctacaat tcttttttat tatacttgat
    36481 attattgtta acacgaagtc ccccgcttca tgtccataag tatcattgat aaccttaaag
    36541 tcatcaatat caccaaggat aagggatatt gatgtttcac tatatttatt aattcttctt
    36601 tgctccataa gttgattaat tatatgtcgc ctattgtaaa gacctgtaag ataatctctt
    36661 acaacgagtc tattcaattt ttcaagagaa gattccagtt cattatttat cttttttaat
    36721 ttatcttgag atttctttac ttcaagatga gctataacac gagcttttaa ttctgtcata
    36781 ctaaaaggtt tcaccatata atcaattgct cctacaccaa atccttttac tatgtctgta
    36841 tctgcatttt ttgaagttat aaaaattata ggtatatctg ctgtgcgagc attagatttt
    36901 acttccttac aaaaatcaaa accagagtta tctggtaaaa ttatatcaag caaaataata
    36961 tctggtataa attcttcaat aaactttttt gcctctattg cattaaatgc ttttttaacc
    37021 ttaaaattat cttttgtaag tgctttatct attaagtcac acatcagaac actatcatca
    37081 acgactaaaa ttgttccctg ttgcttattt ttcatataca aacctctctt aaacataata
    37141 tatttaaatt ttaattattt aaaattttta tacttaataa ttataccact atattcttaa
    37201 atgttctcat aacaatcttt ttataataac attccaacta catccctata ttacatgata
    37261 gtgcaatcaa acccattgat taattcatct attaaaattt catctttatc tgttaaaagt
    37321 ttctctaaat ctagtaaagt aattacttta ccatctaatt ctccaatacc gcttacaaaa
    37381 taatctgaat attctatagt aactcttggt ggaggagata tttcactttt ttctaggctt
    37441 attatatcat caactctatc aaccacaaat ccaactacta agtcttttat ttcagttact
    37501 actatataca tacaatttgt aatcattaat tcatcttttt taagtctcaa acgcatatct
    37561 attattggaa taattttccc ccttagattt attatacctt tagaatatgt aggtagttct
    37621 ggaataaata taatttcttg atttccagta atttctatta ctttttcaag ttcaacccca
    37681 aaatcttgtt catctacttt aaactttaaa tacttaattc cttcatcaat taatccataa
    37741 tctaaatatg ggtcatctgg aaatctcatt taatacctcc ctactaaaat atactttcta
    37801 taaaatctat attatagttt ctttttcccc ttatttattg aatctacaat taattcacct
    37861 gtttcagtat aaaaacgtat tgttcttcca taattcatac ctgtgtcctc agctaatatt
    37921 ggaatattta atcctaaaag agtttttttt actgcctcaa cattcctgtg tcctatactt
    37981 gcaattgctg aattgctatt tcctaaaaac atctgagccc ctccagcaat ttttgctttt
    38041 atatatattc tatttgcacc tatattctcc atagatttaa tgagctcttt tattcctgtg
    38101 tcagcaaatt tatacttatt ttcaatgttg atagcatctt tactatatgg caacataaca
    38161 tgcaacattc caccaattcc agctacttta tctatcaaac atactcctac acaagaacca
    38221 agtgcataag taactaaaac atttggtcta taggctatct tcatatctgc aatgttcact
    38281 actatctccc tattcatatc tctaatccca acttcactag tatttctcta agtgagctca
    38341 tttctggaat catcaaaatg tgactagtaa agtaattatc actcatttta aacttatttt
    38401 ctacaaataa aactttgtca ccaacatctg aaaatcttat cataggcaca tttagaacag
    38461 ctccaaccat atcaatacat atatctggaa ttgaaacact tatagtcatg tttaacatag
    38521 atgcaatagc atttacatat gaacttgcca taatatttcc tatttcttta attgctgaaa
    38581 tttcaatttc ctcaatatca tctaaaggaa cttcttcttt attaaaaaga gaacttagca
    38641 taagttgagt tattgattca tccaacaaaa acataaacat tccattaata tcgcctttca
    38701 tatcgagtaa aatacatact actttgtttt ctggaccacc aagcaaattt gtcgcttcgt
    38761 tatattcaag tatcttgacc ataggtatta atacttctac attactattt atcatggatg
    38821 caagtgaagt aattgcattc ccagagccta tattaccaat ttctctaaga gcatctatat
    38881 gagcatcatc aagttctaaa taatttataa tataaacccc tccctctatt attaaattta
    38941 tttgattttt attgtatcag tatatattta cacttttatt ttaaagcatt atttacaact
    39001 ttaactaatg tttctgtttt gaagggtttc actataaaat ctaatgctcc aagttttatg
    39061 gcatctacaa tcatattctc ttgtcctatt gcagagcaca ttacaacctt agcacttgaa
    39121 tccaactttt ttatttctct tagcacctct aaaccatctt tttttggcat tgtaatgtca
    39181 agcaacatca aatcgggctt ttcatattta aatatattac acgcttcttc tccatcattt
    39241 gcttctacta aattattata gccactttta cccagagcct ctttaattat cattctcata
    39301 aaaatagcat catctactat caaaatttta tttcccataa aactaactcc tccatatgta
    39361 caacaataaa cgcttttatt ttcagttatt atctatacta tcttactatt tttcgctaca
    39421 aaataaatac atttcattga taaataaaag taattactta tgtcatatta tgcttaattc
    39481 tcttaacata atttttcaac aaaaaaactt atatatctat tgtaatatat gtttggtgtt
    39541 ttgacgagtt attaaaaata taattgtata aaacatcaaa agtaatcaaa ttataataaa
    39601 acataacttt ataccttatt tatatttgta taaaaataat tttcagattc attaaaatca
    39661 tttctgtaga tttatataag atttgacttt cttaatatat aatagatagt tgtttattta
    39721 cttaattata tttctatata tgtattatcg attaaattat atttagcttt atacattatt
    39781 ttttatattt ttcaaattgc atactcataa atccaaaagt gttatcacat acttataatg
    39841 ctttttttca tatttcaaat taaatgacaa gtcattatat ttacaagtat cattttacaa
    39901 caaacaatat taaatgaaga atatgtctaa atattcaaag tgataatgat actgttaatt
    39961 attaaaaaag cagtaaatct gtaaaagatt tactgctttt ttaataatta aactttctat
    40021 aataaatcta ctatactcga tacttccttc attcaatata atagtaacaa atctacttta
    40081 ttcctatgta aatatgaatt tcatgtttat ttgtatcaaa agtattactt tgatactctt
    40141 caaaatcact tacataagtc ctgtcaaaat ccatttgcca aaactccaac caaaaatctc
    40201 ctacttcttt ttgacctcct gctataacaa actttgcata cttacctgct ggtataactt
    40261 tactaataat aatttctcca acagtattat tagtatttaa ttcttctaaa ttcttatctt
    40321 tatcagaatt actatttact tcacaacatg caacaaagtt atatggactt gtaaaatcac
    40381 cctggtaatc tgtatataga cctattgtct tgtcactctt cttacccttt atagcattat
    40441 atataccttt gcccataaat tttttccaca attcccctat atcatttact gcttgtccat
    40501 ctttatttgt agtttccttt gatattccta taactatttt ctcacttatc tctactattt
    40561 cataattcat actttatacc tcactttgtt tttattaata tattttactt tgaactaatt
    40621 caattataat ttataatata cgacaccttt atgtcatatt tttaatataa ttaaactcag
    40681 tgagatatta taatatacct aataaacttt ttaatctagc attatattat aaggaataaa
    40741 ttttagacaa ctcctttagt ctagttatta cattatccct aacatcttta ggttcaagta
    40801 cttcaacgtt gtcgccaaag gataaaatat atccataaat ccattcacca ataggaaatt
    40861 ccgtaattac atcatatgta ttatcttcat ttttagttat taaatcttta ttaaaatcat
    40921 caaatactct aaaaagcatc ttttctttaa acctcaattt caacgttata gtattttcct
    40981 taattacttt agagtcattc aagcatactt cttctattac ctttcttgaa aacacttctt
    41041 cctttataga taaattcctt attctactaa ttctaaatat cctaaaatca tcttttagct
    41101 tacaaaatcc atacaagtac caagtcttac tcttatacat aagcttaagt ggttcgacag
    41161 ttctgtttgt ctggcttgac aaactattta cataattaaa atttataata ttacgcctta
    41221 aaatagcttc ttttattttt gtaaatttat catcttcatt aaaattgctt ccccattcag
    41281 taaagtctat ttcaatccag tttgaaaaat tctgctctcc aaatattgaa ccaattttat
    41341 ttactactga atttatttct ggatacttag tcgcctgtaa tgttttcagc gccactatta
    41401 aactctcttt atcttttttt gacaatatag ccttatctat agaatattct tctattaaag
    41461 atatacctcc tcctttgcct ttcatcatat atactggtac tcctgacata gacagagttt
    41521 ctatatctct atagatggtt cttgtagaaa cttcaaatct atctgccaac tctttagctg
    41581 ttactagttt tttatttaat agaattacta ttatttctgt taatctattt attttcattc
    41641 attaccacct actaaaatta ttaaacttat ttaatctaaa ttaattatac caatttttaa
    41701 gcaaataaaa tcttagaatc ttatctagat tattcttata tgattttatt tactatctat
    41761 tatctttctc actttggata ttattatctt aatttactta ttactatctt acttaattta
    41821 cttattgcta tgtcaattcc cttattataa tatcatttgt catcatttta cttaacttgc
    41881 ttattatcat ttactttatt aaatttctat atcaaaaatt agtatctata cttaatactt
    41941 acaattaatt caaagtcttt ccatagtatt tattttttat tatactattc atttcaatgc
    42001 tttctaaacc actctcactc atttatttta aaatttcaat ttactatttc tcaattctat
    42061 gttattattt ttaaatttta tatcactaat tttgaagctt tttaattatt actcatacaa
    42121 tatttaaaca actttttcat aataaagcca tattacaata tattcaaaat atgtaatatt
    42181 ttagatattt ttcgttgaca atgttaaatt tttgttttat ccttaattaa ggacatgtta
    42241 ttgacatttc tgaaacttat ttgaaatagt ttttttattt catttaggaa aacgtattat
    42301 acttaagaaa acgtatttta tcatttcaaa taagtacaat atttattctt ttggggagga
    42361 aatcatggaa attaataaaa aacattttat tcaagtattt ttaacttgct taatcttagt
    42421 agtaatatgt gaatttatag ggcaaagaac tatagctatt ggaaaagctt ctatagtact
    42481 gttccctatg ctttatgcag ttataattgg acttataata acaccagatt tattaggtaa
    42541 aaaaattaaa gcacttaaaa aagtaattgg agaaaaagaa ataaatattg ctggtgaagt
    42601 tgttggaatt gcactagtaa tgcttggtat aaagtatggt actacagttg gaccaaacat
    42661 tgacaagata attcaagccg gaccagcatt cattgcccaa gaatttggtc atatacttgc
    42721 accaatcgtt gcattacctc ttgcattaat gtttggaatg aaaagagaag ctgttggagc
    42781 tactgcaagt ataagccgtg aaccttcttt aggagttata tcagaaaaat atgggataaa
    42841 ctctccagaa ggtagtggtg tacttggtac atatttaatg ggaacagttc ttggtactat
    42901 atactttagt gtcctgggtt caatatctat ctacagtggt cttcacccat atgctttggg
    42961 aatggcctgt ggtgttggta gtggaagtat gatgacggca gctgctggtt cattgtctac
    43021 catggtacca cctgaaatgg cagatacaat acttgcctat gctgcaacaa gcaatatgat
    43081 gtctagcata acaggaatta tattcttagt ttttgtatct ttaccattta ctaattttat
    43141 gtataagatt ttagaaccta aattttcgag aaataaaaat actaaagaaa ttaaatctac
    43201 aaaaggagag tgctaacaaa tgtttgctaa tttaaatttg aagaaaagtt catatcaatt
    43261 attggttatg tctgttattg gggttataat tcttattgga caaagaatta gcgttggtac
    43321 atctatagtt acagctcttc ctggtatggt gatgctaata ttagctgcta tggcggctat
    43381 gattataaaa gatttatttc ctaaatcaat ctttccagct tttggatttg caactataat
    43441 aggcctttta cttagtatgc catatagtcc aacatctgaa gtattcttaa ctaacactaa
    43501 taatattaac tttatggcta taactactcc actactagct tttgcaggaa tttctgttgg
    43561 aaacaaaata gaagctttaa aagaaatgtc atggaaaata gttataatct cacttattgt
    43621 atttacaact atattctttg catgtgcgag tatagctcat atagttttaa gtattcaagg
    43681 taaaatatag gaggaattta ttatgaataa agaacaatta aaatctctag taataaaaac
    43741 tatagatgaa aatagagaaa aaatattaaa aataggtcaa ggaatataca ataatccaga
    43801 atatggatat aaagaattta aaactacgga agctgtttca aacttttttg agcaggaatt
    43861 aaacttatct gtagaaaaaa acatagcagt tacaggatgt aaagcagatg caaattctag
    43921 caaggaaggt cctcatatat ctatacttgg agaattggat ggtatatcat gtaaagaaca
    43981 taaagatgct aatgaaatag gtgcttctca tacttgtgga cataatattc aaatagctgg
    44041 aatgttaggt gccgctgttg gtttagtgaa aagtggtgtt ttagaacatt tagatggtaa
    44101 agtatctttt atggctactc cagctgaaga gtttattgag ttggaataca gagaacaatt
    44161 aaaaaaggaa ggaaaaataa cttattttgg tggaaaacaa gagttaataa aaagaggtta
    44221 ttttgatgat atagacatat ctatgatgtt tcattcttct gatttaggag aagataaggc
    44281 tctagttggt cctgaaagta atggatttgt tggaaaaaaa gttaaattta taggtaaaga
    44341 atctcatgct ggttctgctc cacatgatgg aataaatgct ttaaatgcag caatgcttgc
    44401 tataaataat gtaaatgcac ttagagaaac ttttaaagag tctgaaagag ttagattcca
    44461 ccctatcatt acaaaaggtg gagatatagt aaatgttgtt cctgctgacg ttcatatgga
    44521 atcatatgtt agagctagaa ctataaatgg tatgattgat gctaatgaaa gaataaataa
    44581 ggctttgatg gctggtggga tggcagttgg agctgatgtt aagataactg aaattcctgg
    44641 atatcttcca atattaagat acaaaagcct tgataattta tttaaaaaca atcttgaaga
    44701 tttaggtcta aagggaaaag ttattgatgg tggagatttt acaggttctt ttgattttgg
    44761 agatgtgtct catataatgc ctactcttca ccctatgatt ggtggtgtaa aaggagctct
    44821 tcatacaagg gattttgaaa tagttgatga agatttagct tacatagttc ctgctaaagc
    44881 aatggcactt acagttgtag accttctttt tgacaatgct aagaatgcta aagatatatt
    44941 ggatgccttt actccagtta tgactaaaga agaatatcta acattcctag aaaaacacga
    45001 taaaacttta taagtctatt tttataatac aaaattgagt gtctaaagat gaatttttta
    45061 gtttattaga cactcttttt tgtatgaaat caaatatatt tttatagttt tagttataaa
    45121 aaagtctata tctattttga gaaagatatc cttattatca tttattgtta tatctgccta
    45181 ctatttgtcc ttttaacttt taaacaaaat aaatacccta atataggaat taaaataaaa
    45241 aatattatct ttaataaaac tcaataaaat caataactta atcttccact agctttttat
    45301 aaaattttgt tttaaaatta attttaaaga ttatatactg caaagatata ttaaatacaa
    45361 ttcatcataa atctacttaa agtatattta actaacacta ctcaaccaga aaattcagaa
    45421 aactgcattg acataggaaa aagtttattt tatacttttt ttaggacata ttgtggacac
    45481 gtcttaaatc aacaagcaga atttacatga aagcttaacc acaatactta ttttttaatt
    45541 atatttttaa atattaggga ggatattatg aatgataacg tagttaagaa gaaaaacttt
    45601 tttgacagaa cattaaacag aatagaaact gttggtaata aactaccaga cccggttacg
    45661 atatttttag ggttatgtgt acttttactt atactatcta gtgtagttgg ttctatgggg
    45721 atatcagtag ttcatcctgg tactggagaa actataactg ctgtaaattt attgactgta
    45781 gaacaacttc aaattctttt aggaaacata gttagcaatt tccaaggttt tgctccttta
    45841 ggtctagttt tagtaactat gataggtgct ggtgtatgtg ataaaacagg acttatgaca
    45901 gcaacaatca aagcatcagt aagcaagatt cctgaaacaa gagtaactct tgttgtaatg
    45961 actataggta tgcttgccaa tatagcttca gatgcaggta caatactatt tccaccatta
    46021 gctgcacttg tatatcttgg tgttggtaga catccactta taggtttatt ttctggatat
    46081 gcagcagtct gtctaggatt tgctgcaaac attatgataa gcgtcaatga tatacttgct
    46141 gcaagtttta cagttccagc agctcagatg attgattctg gatttcaagc caatgcaaca
    46201 atgaacttat tttttatgat agcatcaact tttgtcctaa tacttttggc aacatgggta
    46261 acagaaaaaa ttgtagctcc tagatttggt aaatatgaag gaaatgcaaa attagatgtt
    46321 gatggaagcc ttagtgatgt agaaaagaaa gggcttaaaa aagctggtat aagtatatta
    46381 atatatgtag ctattatagt agctcttagt gtaatcggta aaaaaccatt cttagctgac
    46441 ccggaaacag gagatttact atcaaacaat gctcctctta tgaagggtat ggtacctata
    46501 atagcactag cattttttat acctggtgtt gtatacggaa aaactatagg taaaataaag
    46561 aaggataagg atgtagtctc tataatggct agtgcaatga gtgatatggg tggatatata
    46621 atactagcat ttgctgcttc tcaattttta caattattca caaatagtaa tttgggtctg
    46681 atattagctg taaagggtgg agaattttta aaatcagcag gaataaatgg acctttatta
    46741 ttgataggat tcattatatt atcatgcttt ataaatttat ttataggtag tgcatctgca
    46801 aagtgggcta ttcttgcacc tatatttgta ccaatgttta tgatggttgg atacaatcca
    46861 gcacttactc agatggctta tcgtataggt gattgtataa caaatccact tagcccatta
    46921 tttccgtact tccctattat actagcattc acaagaaaat acgataaaga tgctggtatg
    46981 ggtactgtaa ttgctaatat gataccatat tctatatcat tcttaatagt gtggactata
    47041 ctattgatat tgtttatgat atttaatatt ccactaggac ctggaatact tccttcatat
    47101 agcatgtaat ttatttaaat ctttctaaaa ggagaaataa tttatgttgg ataaaaatag
    47161 acttataaat aactttatag acatggttag aattgatagc ccatctaatc aagaattaga
    47221 aatgtctaag tggttggtaa actacttaaa agaaagaaat atagatgcca ttatagatga
    47281 tgcaggtgaa aaatatggtg gtaacacagg taatgtcatt gcctatataa agggtgaaga
    47341 aggaagtaga ccactttgtt tatgtgcaca tatggaccaa gttcaacctt gtttaggtgt
    47401 aaagccagta ctagatggta atgtagttag aagtgatgga actactacac ttggtgcaga
    47461 tgataaagct ggaatagctg ctatacttga agctttagaa catgttatta cagaaaaaat
    47521 accacataga gatatttatc tttgttttac aatctgtgag gaagctggta tgcatggtgt
    47581 caaaaacttt aatcctgaaa acttgccttg taaagatatg gtgattttag attctggtgg
    47641 agctattggt tcgatagcat acaaagctcc tgctcaacaa tctataaaaa tctcttttca
    47701 tggaaagaaa gcacatgctg gtatagaacc tgaaaaaggg ttaaatgcta tattagtagc
    47761 ctctcatgca ataagcaata tgcacatagg cagaatagat tcattgacta cctcaaatat
    47821 aggtaaaata gaaggtggtg gagctacaaa catagtaact gatagggtta cattgactgc
    47881 tgaaattagg tctcatatcc ctgaaacttt agagtatgag cttaatcata tggaaaaatg
    47941 ttgtaaggat gctgcatcta aatttaatac tacttatact tttgaacata atatgtctta
    48001 ccctagtttt gaacttagta gagatagtca tgttttcaag ttaagtgaag aagcaataag
    48061 acaagtcggt attgttccaa atccaatggt aattggtggt ggaagtgacg caaatatatt
    48121 agctaatctt ggatataatt gtgctatatt aagtctaggt atgtatgatg tgcacacggt
    48181 taatgaatat gtaaatatag atgaattata tgatactgcc aaaatagttt atcatatgat
    48241 taaattataa atatcataat ataactcttt agattataaa aataaaaacc tatgtatctt
    48301 caactttaca agttatatat taaaaagttg ctttacatag gttttagttt tttatatagt
    48361 aatttattct agcattttta ataataagct ttagtttttt atatagtaat ctgttgtaat
    48421 atatttcata ataagcttta gttttttata tagtaatttg ttatagtatt ttttataata
    48481 agctttaata tattatatag taatttgttg tagaaattta tatgatataa tgatttatac
    48541 agctttataa agtatcttaa aacagtattt cagtaatatt ttttggtctt cctccaccaa
    48601 tactagtctc ttttgcacat attcgaccta aacctgcatt tactatttta tttaatatac
    48661 gtcttgcact tctttcactt acatttagat actctgctaa ctcttttgaa tcataaatct
    48721 tactttttct attctcactt atagcaataa tttttgcaac cgactcacaa ctcattccag
    48781 tctttttaga tatttctatt accttttcat cagatagcat caaagaataa tttaattcat
    48841 tttctgaagc taaaggtcct cttatgtttt catcttcatc tactaaatat ataccaattt
    48901 cttttgaatc tatggagtat cttaatgctt tatgtgcatt attttcagcc tgatacgcag
    48961 ttactccagt accaattcct atactaagag aaaagcccat gtcttttatc tctctcttta
    49021 gcttgaatag cttatcataa ttatactcat tatcagctac ccctttatga acaaatacaa
    49081 cataatcatt tcttccaagt aaaaataagg aaccttgaat acttcttaca tagtttacta
    49141 caagcttatc catatcagat ttttttatca tgtcagaata atagttatct atcttctctt
    49201 tataatctat tagactcaat atttcgacag caatttgaga aaatcttgcc ttgcttagag
    49261 catattcact ctttacctta tcataacttt ctttgattaa ttgtatagta gcttgtaaac
    49321 gaaatacagg atagcctctt tcttttaatt cattatatac tgcaccaaaa ccagttaaca
    49381 ttatatctgt cttattttct tcaaataatt ttatatgcca ttctacaagt tcagactctc
    49441 ctacttccaa agagaatgga ttacaaaata cactagttgc tttaatatca aattctttaa
    49501 gcgcatcttc cacaacatat ctatcaacta catctatact gaatttatct aattttatat
    49561 ttgcactttt tattgcccaa aatgccttca ttatactagt cccacttctc ggtacaaatg
    49621 aatgtggctt acttatctca tacttagatt ttataaattc ataaactgca catccggtaa
    49681 atataatagc atcacattca tcttcacatt tagaaataac ttctattgta tctaccactt
    49741 tttctcttac atatatttta gtctttaaat cattgtctat ctgttttaaa tcatccttta
    49801 tcttaaaccc agagtctgaa ggacctataa tacccactat cataaacttc gctcctaatc
    49861 cataaatatt atacttttta aaaattatat cctcactatt ttttgcttct atttaattat
    49921 tttgaactac tccatcctac ctacgtttag aatggaataa ttcgcttatt tttgataaag
    49981 taacttctca aaatcatcac ttggaatagg cttacaataa taataacctt gaattactac
    50041 acaatccaaa cttactaaaa attcagcttg ttcttttgtc tctacacctt ctgccactac
    50101 atccatatct aaatcttttg ccatggctat agtgtgcttt aaaactattt tttctctatc
    50161 tgtgattcct tcaccattaa agaaaccaca atctatcttt aatgtatcaa tattaatatt
    50221 ttttaacata tttaatgaag aatatgctga accaaagtca tccatattta aaacaatacc
    50281 atccattcta aggtcagcta ttaccttagt gaataatttt atatttttaa taaatagact
    50341 ttctgtaagc tctaattcta aaaaagattt tggtatacca tatttattta ttaagcttaa
    50401 aacaatttct ttaaaatgtg gattatgcaa atgtaatctt gatacattta cagagatagg
    50461 aactggctct tcacctaaat ctatccattt tctaatcaaa gaacatactt gttcccatac
    50521 atacatgtct aatttgataa taaacccatt cttttcaaat agtgaaataa atttaattgg
    50581 aggtattata cctttttctg gatgaaccca tctaaccaat gcctctgccc caacaatttt
    50641 atttgtatta agattatact taggttgtaa atatacatga aattgtccat tttcaagtgc
    50701 atattccatt tctctttcca tatgtttttc ttcaagtgca tcatttctta tagtatcatc
    50761 ataaaatata taatgattga tactttgttt ctttactttt ttgtgagcat atcctgccat
    50821 ttcacatgca cttgtaattg ggatatggtt atccaaaatt ttataaaccc caaaacatgg
    50881 tactaacata tattcaaatt ttttcctatt caagttattt ttaatattat aaattacttt
    50941 atgaatctct ctatcagagt aactctcata aaaaatgcaa aatacatctg catacatacg
    51001 acaacatata ccattagaac caatgttttt ttgaatcaat tctgcaacat atattaaggc
    51061 tttatctcct cctctaattc cataaatatc attaattact ttgaacttat ctatatccat
    51121 cattataatt gcatagcgct tgccaggata tcttttcagc attaagcttg tttgttcaca
    51181 aaaactttca taattgtata atcctgttaa tgtatccttt tggtttttat gtatttgcat
    51241 aagataatct atatttttaa tagcaactaa aatatgtgtt tgtttctcac ctaaattatt
    51301 tttactgcta atcttcagaa tataaagtaa tgcccaatgg tacttttcat ctattcctaa
    51361 gtgtctatac tcaaaattta gttctaaatc accttgtttg ctattattag gactatcaat
    51421 agattttaaa aggaggttat catcaaataa tattatatca tcagggtgaa tcaaatgctt
    51481 tttaatgtat gagaaaattt tctcaatatt ctcttttata ggaaaattta aaatattgct
    51541 ctctgattga taaattggag taattaaatt tgtatccatg caaatagata aaattatatc
    51601 atatgtatta taagctaatt tttcataagc cttagaatac ccttttatca ttaaatcatc
    51661 aaaatacact tcattatcta aatctctaca tttaagtgaa atattatttg ttgaatcgct
    51721 taaatcacta actaccttca tttcattatt tctaagttcg attttattat agtatcgttt
    51781 cttatcttgg tacatcctct catcagcaac tttaattaac ttatgtatat caatatcatc
    51841 ttcactccaa atacttccta ctgctgcact acattccatg ttatctttaa gttcttcagt
    51901 tagccaactt actaattctt caaataattg ttttgagata tcttcacata atacaacaaa
    51961 ctcatctcct ccaatacggt aaacataata agaatgaaag tatttttgta tcattacact
    52021 gactgacata atgatggcat ctccactagc atgtccaaag ttatcattaa tatcttttaa
    52081 tccatttata tctatgaata caactcctat agatttaact ttgtcttttt gaaaagtatc
    52141 tatatactta atatatctat ttctattata tgcactagtt aagaaatcat agtagctcat
    52201 ataatttaat ttattttcta cttttctttt tttcatttca gttaataaaa aataagatag
    52261 ggatgtcaaa agagaggtgt ctccaacagc cttacgtgga ttatcgactc caataaatcc
    52321 tattatttta tcatcttctt ttaatgaaga cgccattaaa cttttgattt tttgaggttt
    52381 taaaatttca tattccattg gatgctcttc ttttatatct tctacatcgt caattattat
    52441 aaatcctttt tgcttaaata ataaaaacca attttttaat tccttaatat caagatttgt
    52501 tagtaactgt ttttgttcat caacaccttc attacaccat tcatatgtat taattacttt
    52561 ttttctatct tctgatactt caaaaacata tgctctatca gctttatgaa atttaccaat
    52621 actgcttaat acaaggtcta cagcatcaga aaaactagat tctgttataa gatgtttaat
    52681 acatccaact aatagctcct ttatctctaa cttttctgat attgatttac ttatattttc
    52741 cttttctgta atatcaagag ctatttctat ccttgcaagt ttaccttccc atttaattaa
    52801 cttgtccttt aatataaagt gtctatttat tagagtattt gtattttccc atacgtaata
    52861 tccatcttct tttaaaatag aatttgtaca aaattcgcaa ggagagtctc taccttgtat
    52921 tgcttcataa catttcatat tagatatatc attaatcctc agtgcctttt tcccaatttc
    52981 attaatatat aaaagttcat atgtatctaa agaagaaaca tatacaattt catccaattc
    53041 atctattaaa tttattacat ccatttatat atatctcctt ttattcattt tcccagattg
    53101 aattttaaat cttttaaaat tttgctatgt atttagcaat gatgttatgc ttctttatat
    53161 tttaaaatag caccttaata aagttctatt ttttagtcaa tagagttatt atcgtgtcaa
    53221 ttgtacagta gagctttgta atacttaatt taatatatct ataattaatt atcgtattgt
    53281 gtatttacaa ttaatcatca tataaataat aaatctccac ttcaattaag tattccaatc
    53341 atatagaaag ataatacttc attcatttaa aaatataaaa ctattatata ttaagatttc
    53401 tcaatattaa taagttattt agtttgttac ttttatatat tatataatat cacaaaggct
    53461 gacataaaaa gataaaaagg gcaatttttt tatatcaaaa aagagttaaa ttgatttatc
    53521 catataaata ttatatctaa caattctact tacttttctt acacttatta gcatatagtt
    53581 ttcgagagct tattacaaac taacacttag cacaccttaa aaaatatggt ctgataagta
    53641 atcatacaaa gaatacacga taaaccataa aatatgacat actttttcac gtcatcaaaa
    53701 ctgatgattt cactattaat atatgataaa atatgcttaa taaattaaat tttaaaggga
    53761 gaatagttat gaaaatattt agtttcatgt tgtatgtggt gggaatatgt ttttgtattg
    53821 ctggatttat aggacattac ccagcatttg ctggtgcaac attgagtttt tttgcaacta
    53881 caatgatagc cgtaaaccaa ggcaaaacta agaaaaaaat gaaataagta aatgccaact
    53941 ttacaagcta gtattacaca agtagttagt ctaaaattgg cttacttttt ctattataga
    54001 aatacatcat caactttaca ttctcttgga aaaataaaaa tagctatgta aattcaatat
    54061 tagatagact aactctctat ccatttcatt ataaaatata catagctatt tgtattcgat
    54121 ttaaaatact tatattttct tatataacaa ataatttcta tctgattact actcatattc
    54181 atttggtgac cactcatcaa ctacccattt agtatctatt catctgccat acggtaacct
    54241 accccaacct cagtcaaaat atattctggc tgagcaggat tcttttcaat ttttcttctt
    54301 atacttgcca taaaaactct aagtgactga ttttcacttt catagtaatt tccccaaact
    54361 ttatctatta tgaacttatg agttaaaact cttcctgaat acttagacat caactcaata
    54421 atcttatatt caattggagt taaatgtatt tcttcatcat taattaacac agtatgattt
    54481 tcataatcta tctttaggtt tttgacttca aaagattttg gagcatcatt atttatattg
    54541 ccttgttgag ctttatttct aagagctaca cgtactctag ccaaaagctc tgttacacta
    54601 aaaggtttag ttaaataatc atctgcccct ccatctaaag cctccacctt atccctctca
    54661 tgctcccttg ctgaaacaac aattatttta ttagtcttgg cacatgccct aactcgtcct
    54721 attacctcaa ttccatcaat atctggtagt cctaaatcca aaattatcaa atctgggtca
    54781 agagaatgta taagtgatat agctgttcct ccattatctg tctctacaca cctataattt
    54841 tgagtttcaa gagatacttt tataaattta caaattggct tatcatcttc tacaattaaa
    54901 actaatggct ttatttccac ttgtcttttc cctcctcatc atacacaggt atgctaaatc
    54961 taaatgtagc tcctccagaa ggattattaa aggcgacaat ttctccacca tgagcttcta
    55021 ctatagattt acatatctcc aatccaagac caatacctct tctttcaaga tttctagact
    55081 tattcttagt ataaaaccta ttaaaaatat taccaatatc ttcatttggt attccttttc
    55141 cattatctgc aacttcaaat agcacttgac ttgactcttt ttttacagtt agttctatct
    55201 tagaattttt aggtgtatgc cttatagcat tatcaattag gtttactaaa acttgttcta
    55261 tcaataatac atccacatgc acgattatta tctcatctgg aatattggtt tttatatctc
    55321 tactattggc aaactttttg actcttaata tagactctgc tattatttca tcaacaacct
    55381 ctggtcgttt ttcaatatcc aattttcctt catctattct ggtcatacta agtatattct
    55441 caacagaatg agttagccaa ctcgtatctt catatatatt ttttaataat tccactctag
    55501 tttctttatc tatcacatca tcattttcaa gtatagttga agatgaaccc aatatacttg
    55561 taagtggagt tcttaaatca tgagaaattg acctaagcaa gtttcctctt aatctctctc
    55621 tctctgcctc aagatttgct tttttatttt tttcaaataa attttctcta tcaattgcca
    55681 acgcaacctg tgttgaaact gcttctaata gtatcttttc attttctgta ataatatcta
    55741 tcttaaaaca cgcaatacct ataacaccaa gaacatttga ttcttgacct tttataggaa
    55801 aataatatgc actgctgttt ttacaatatt ttgtcccaat tccaactggg ttacccgtcc
    55861 taaaagcttc ttttatagct tccttttcta atactgaatg gaatatattc tcacttccat
    55921 cattattaca aatataaata cttggcttac ctagattatt attttcatct gcaatagtca
    55981 ctattacagt tctatttaat atatttacta aattagaccc acaaaattca ataatttgat
    56041 ttttattttt tgctttaagc aacgttttgt tattctcata aagtaatctt atcatttttt
    56101 ctctcttatg agaaagtctc acttctcttt ttatcctaga agttaaagta cttgttataa
    56161 ttgctgccat cagcataata caaaaggtca tagggtaatc ttttctataa gctaaaaaag
    56221 tatataatgg atgtgtaaag aaaaaattaa atgatagcac tcctattact gaagaaagta
    56281 ttccaaaaaa atatccatag gttatacttg tagcaaatag tacacctaat atatatacta
    56341 gtataatatt agattcatta aaacctactt tttcaaaaac tactgatatt ccagtagcaa
    56401 ttgtcataac taatatagtt tttatgaagt ccttaataat tatcttttta ctgagataaa
    56461 catcttcatc ataatcatac tcttttaagt cttcatgttg tagtcgttcc tttttcattt
    56521 actacaattc ctccttattg ttactgttta aattggctct attttatata atacaatttt
    56581 atcataataa attcaatcaa tacatttaat taatgtattt aaattactaa aaggtgctgt
    56641 cttaaaatga aaataaatct ctatttcaaa acagcacctc tatatattta aattgataat
    56701 ttaattttta tatacttaaa ttattagttt tatttaattt cataaattat aatacttgat
    56761 ttatcgaata ttcttatcca acgagcataa atataaagtg ggcacatata cctgcacata
    56821 aaccacctat agtatgcgaa agtatcgctt taccagctaa tggtcttgca tctagagcat
    56881 ccatcatacc tatgtgtgta cttaaatatc cactccaaca catacccatt gctgtgaata
    56941 ctgctatatc attaggagtt atagcgcctg attttataaa ctctggtact aaagatattg
    57001 ctgctccaac agctcctaat gcagttacag ggaatgctat tgcttctggt gatgtaaatc
    57061 caaataatgg ctctattata aagctaatct tatcaccaat agcaggtaat aattttatac
    57121 cttcatatgc agctcctgtg taaacagcct gacctgtagc agggtctgta gatggtccaa
    57181 aagttaataa cataactaat gtacaaacta ctaaaacgcc tggtattata gccataccca
    57241 tttcaacacc taacttacca ccttcaagta tagcatccaa tgttctttgg aatacattac
    57301 catctcttat ttctctaaac tcttcaagtt ttgcaccttt atcatttatt tgcttttcag
    57361 tatcattttt agggtcataa ttataatact ttttagtaaa agtcaacata attctaacac
    57421 taataatact acctattatt gcgccaacat tacctattat agctggtagt acatattctt
    57481 taccttgagc tatcataaaa gttgttacaa taagtcccat accaaaggct gttcctaaat
    57541 tacataaagc aggtacttga tacttcttaa aatattgtgt aaatgttttg tctttagcaa
    57601 atggtataat agctggatta tcagataaat atgttgcaac tactcctgct atactagcac
    57661 caggtaagcc ccatataggt ctcataagcc ccttaaatat cttattaact aaagatatta
    57721 ctccaaactc tgaaagcaac gcactaagtg cacctgcaag aactgccata gccattatta
    57781 aaaatactgt gtctaataaa agcgcatgtg ctgtactcat tattacttta aacatcattc
    57841 ctgcacccat gatgcttcct acatatccaa atcctaccgc caatagtaca ataaatacga
    57901 aggtttccat acttactgcc ttgactcttc tcttatccga cagcttttcc attttgaaat
    57961 cttccccctt ttaattttaa attaaggttc ctaacattgg tacaaacttt ttggtacaaa
    58021 ctgagttcta aaacttacac tcgtaatgca agttgtcagt tttttgaaat aaaaaaatta
    58081 cgttcataga ataagaatat catctttatt ttggatactc ttattctatt ttatgttatt
    58141 atattatcat ccttttgttt aaaagtcaat tttttctatt tttgttgttt aattttattt
    58201 atactatttt tatatttttc attttctttt atccttgtaa gcactccata taagttgact
    58261 tttctaaata cagtagttat aaataccaaa cctaatgcaa ttgagcttgc acatgataat
    58321 gtactcacac catattctac agcttttata taattattgg ttaaaacaga atacatagta
    58381 ttatatattc cataaccagg tactaatatt attaaacaac aaacacttaa tgtagttgct
    58441 ggagtcatat aaattcttgc acataactca caatatatcg caaaacaaac tgtagctata
    58501 aaaaaacata agttttctgt tactcccata tttaaaagaa atttatatga aaaccaagct
    58561 atacttccac ctattcctgc taatattaag ttttttcctt tcatattaaa tagcactcca
    58621 aagcttaagg cagtaaaaaa agctgctatt acttctataa acaaatgcac ttatatcccc
    58681 cctaacttga agtacaatcc aagtaccaag aacattccta ctgctataga tacacctata
    58741 aaaaatactt ctgctaattt tgcaagacca gaaatcaact gtccatctaa caaatctctt
    58801 agtgcattag tcaaagcaag cccaggaact aaaagcatta ttgctcctgc tattagatgg
    58861 tctagcgtct ttataaatcc aagctttaaa atcaaaattg aacaagaagc tataataact
    58921 gctccaattg catttacaaa aaagtcatta agggaagatt tacttaagta cataataaca
    58981 aacttagtca aaatcccaac agtaaatgca gctataaatt cttccacatt tcctccaaat
    59041 aatatcgaaa aagttgctgc tgcaatacct gcaaaaaata ttgttattaa atctgagtaa
    59101 tagttatctt cacttatttc atccaaaatt ttctcacata attcaatatc taaattattt
    59161 atacttattg ctcttgataa tgagttaact tcatgaacca agtttaggtc tactcttctt
    59221 gagcttattc ttttaattgc tgaatgtaat tttccatcta caaatacaga tgccatcaca
    59281 gctgttggag tagcaaatac gtccacatga tctattccaa aagattgaca tattctagct
    59341 atcgtttctt caactctata ggtttctcct ccgctttgca acatagcttt acctgcattt
    59401 gaggaaaagt ttaaaattct atctatatcc acaaaacata tctcccattc ttttatagta
    59461 ttattcatat tttaatacaa gttattattt atttaaacta tttcaaataa ataatatcca
    59521 atatttacat tttatgaaaa aacttgtttt ttatgcttgt caaaaccaaa ttttaaggtt
    59581 gtttacacca taaaatggct gaattaatat ttgacaaaca ctttcaacca tttatataac
    59641 cttctaaatt gtataacttt ttactacaaa taaaattata tctcttttta ttctttctct
    59701 tggctcttta agtttacagc aacttcatat ttatatatgt acaatataaa atattatttt
    59761 tatgatacaa aata
//
LOCUS       DAMKOJ010000015        57757 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000015 DAMKOJ010000000
VERSION     DAMKOJ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57757
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.016"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            727..1929
                     /locus_tag="PC592_001025"
     CDS             727..1929
                     /locus_tag="PC592_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF4055031.1"
                     /translation="MKASILITLIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGAVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            1934..2704
                     /locus_tag="PC592_001026"
     CDS             1934..2704
                     /locus_tag="PC592_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055032.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSSIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYENYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSERSDIELSSGNSNLYKYKKETVNQDIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNNDYEVTVSRSKVKEFRLLMHI"
     gene            2850..4271
                     /locus_tag="PC592_001027"
     CDS             2850..4271
                     /locus_tag="PC592_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF4055033.1"
                     /translation="MVSFLGSIVVLIVGYFIYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGIYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            4537..5019
                     /locus_tag="PC592_001028"
     CDS             4537..5019
                     /locus_tag="PC592_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF4055034.1"
                     /translation="MDTKKYKDKLLKERESLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGTCDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            5068..5847
                     /locus_tag="PC592_001029"
     CDS             5068..5847
                     /locus_tag="PC592_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4055035.1"
                     /translation="MKKSIWGICICLLSIVGVYTYNHNTHNQDDLKEAYSLSENKISD
                     YEDVIIKKGSDDEKVIALTFDDGPDEVFTPQVLDILKKNNVKATFFVVGEKVEYNKEL
                     LKRQYTEGHEIGNHTFTHINVAKNSYDKVEKEITDTQNAVKNVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKKMNIILWSNLDPRDWSNPGVGNIINTILTKVQNGNIILLHDYNNRRN
                     DKSQTIQALEVVIPKLKEKGYKFVTISELIQHLDKNKQVQK"
     gene            6006..6452
                     /gene="lspA"
                     /locus_tag="PC592_001030"
     CDS             6006..6452
                     /gene="lspA"
                     /locus_tag="PC592_001030"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF4055036.1"
                     /translation="MLYILIIILLIGLDQLSKMWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHISGKLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            6421..7368
                     /locus_tag="PC592_001031"
     CDS             6421..7368
                     /locus_tag="PC592_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF4055037.1"
                     /translation="MFYFLKVKVGDLMYEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKIEKAKYLVKEEDNIVIEIPEPKVLEVVPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKENKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRAKLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            7727..8260
                     /gene="pyrR"
                     /locus_tag="PC592_001032"
     CDS             7727..8260
                     /gene="pyrR"
                     /locus_tag="PC592_001032"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDF4055038.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDVTLYRDDLEKIDVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            8543..9751
                     /locus_tag="PC592_001033"
     CDS             8543..9751
                     /locus_tag="PC592_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDF4055039.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFNMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILGLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAFILLIGLGTTYLSNKGISIGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEE"
     gene            10039..11691
                     /gene="abc-f"
                     /locus_tag="PC592_001034"
     CDS             10039..11691
                     /gene="abc-f"
                     /locus_tag="PC592_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HDF4055040.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYIYLTESYSYISQSENNIEICSDSKEKSLLNAPDRFEEYLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEEMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRAYFEYQEYVKEKKRLEKALLHKKSLS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKASIEMKIK
                     IQNGMEIISKNLVEIKDMTLKLGNKLLLDNVSFKIKRGKKIALLGDNGCGKSTMIKEI
                     LNNKNDNIKINNKVKVGYFDQHQSLLDEAKSVLYNTKVNSSFDESFIRTNLNLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLIFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDTKIREFDCNYDEYIINRNKKNPSRESKIKKENLLV
                     LENRLITIVSMLSIEKDGLKKELYESEYNELLKQINKLKNSF"
     gene            complement(11884..13659)
                     /locus_tag="PC592_001035"
     CDS             complement(11884..13659)
                     /locus_tag="PC592_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDF4055041.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTIKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDAISKDLFIKNLEESEESIFKSIYSKFLGISPIIAKEICYRAG
                     INQNTIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIVIDKKVDRVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNNVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFMSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            13955..14989
                     /gene="ltaE"
                     /locus_tag="PC592_001036"
     CDS             13955..14989
                     /gene="ltaE"
                     /locus_tag="PC592_001036"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDF4055042.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDENGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVGLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKDFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            15276..16106
                     /locus_tag="PC592_001037"
     CDS             15276..16106
                     /locus_tag="PC592_001037"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDF4055043.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDSEFKVTSMLM
                     GVPHTVVIVDELDVEDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            16110..16991
                     /locus_tag="PC592_001038"
     CDS             16110..16991
                     /locus_tag="PC592_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDF4055044.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            17021..17638
                     /gene="gmk"
                     /locus_tag="PC592_001039"
     CDS             17021..17638
                     /gene="gmk"
                     /locus_tag="PC592_001039"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDF4055045.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKSAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            17641..17907
                     /locus_tag="PC592_001040"
     CDS             17641..17907
                     /locus_tag="PC592_001040"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDF4055046.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKAKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            17912..19111
                     /gene="coaBC"
                     /locus_tag="PC592_001041"
     CDS             17912..19111
                     /gene="coaBC"
                     /locus_tag="PC592_001041"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDF4055047.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVNPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GAGKLANPDIIVEEVLANLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAISRGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILVGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            19350..21875
                     /gene="priA"
                     /locus_tag="PC592_001042"
     CDS             19350..21875
                     /gene="priA"
                     /locus_tag="PC592_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDF4055048.1"
                     /translation="MNSILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSEVI
                     RIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIESKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQKAVDEIKSNMFLDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKYGEYKLINIKSRANDKPLPNIEVVDMKEELDKGNRSIFSL
                     KLQKEIRCAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DDILNKFKDKKADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVVKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNISVSIDINPNSVL"
     gene            21893..22333
                     /gene="def"
                     /locus_tag="PC592_001043"
     CDS             21893..22333
                     /gene="def"
                     /locus_tag="PC592_001043"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF4055049.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHELDHLDGILFVDKIEK"
     gene            22348..23277
                     /locus_tag="PC592_001044"
     CDS             22348..23277
                     /locus_tag="PC592_001044"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDF4055050.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDTIKSLNPDVIVVVAFGQILPKGILEIPKFG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDAGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            23287..24039
                     /locus_tag="PC592_001045"
     CDS             23287..24039
                     /locus_tag="PC592_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HDF4055051.1"
                     /translation="MTDIKKYLTSVGILILILGLLIGVVNFFIISLTQIFSLIINIII
                     ISLILIILCSTAVTYRVIKGKNINSNIMKINFNIVSGLFPIISFIASSFGMSKSEIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCEECGRCNVGELI
                     KLKEKTNVKIFVATGGTLARKIIIDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMIDIEKAIEFLTGKNILACN"
     gene            24108..24809
                     /locus_tag="PC592_001046"
     CDS             24108..24809
                     /locus_tag="PC592_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDF4055052.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            24871..26196
                     /gene="rsmB"
                     /locus_tag="PC592_001047"
     CDS             24871..26196
                     /gene="rsmB"
                     /locus_tag="PC592_001047"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDF4055053.1"
                     /translation="MDAREVGFKVLCDIEKNNNYSNIAINKHFKNLEISDIDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANSEKPSIYIRTNMLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEDSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLIKSTVNRLGLKNVCVERFDASEIDENSISKFDYVLADVPCSGLG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASRYVKVGGTLVYSTCTIQDDENINIVAS
                     FVEENHNFEFDSIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            26204..27235
                     /gene="rlmN"
                     /locus_tag="PC592_001048"
     CDS             26204..27235
                     /gene="rlmN"
                     /locus_tag="PC592_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF4055054.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     EDMNNIPKSLRNKLEEISCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIKEILDACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            27255..28007
                     /locus_tag="PC592_001049"
     CDS             27255..28007
                     /locus_tag="PC592_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDF4055055.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            28024..30027
                     /gene="pknB"
                     /locus_tag="PC592_001050"
     CDS             28024..30027
                     /gene="pknB"
                     /locus_tag="PC592_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDF4055056.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPILAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     EEEEEIMRAKKNQRTKSAPSKRTKKKKKKQESPKSRRRLKVIATVLILILCAQVFLAY
                     KFLFSGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCIISQTP
                     EGGSTNIKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYEYSSI
                     YKEGTVLNQSPGAGSSRVQEGDEISLYVSKGSEKSNTQTPTVPNKTPTTPNNDTPTEP
                     GSNSGSSGGSSGGSNSGNSGGNSGNNGNNSGGSNSGNSGGNSGGSNSGDNGGNSGGSN
                     SGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            30135..30872
                     /locus_tag="PC592_001051"
     CDS             30135..30872
                     /locus_tag="PC592_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF4055057.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTRLNEENFSIKLFKADVSNREDVENMVDYCIKEFGGLDVLVNNAGISQDKLFTDITD
                     VDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDILVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            30970..31854
                     /gene="rsgA"
                     /locus_tag="PC592_001052"
     CDS             30970..31854
                     /gene="rsgA"
                     /locus_tag="PC592_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF4055058.1"
                     /translation="MLEGKIIKGISGFYYVDTHNGIYECKARGIFRKHKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKKIYELSGYKVIPVSNITKLNIEKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVANGEISKERY
                     ESYIQLLNEIRQNNSRRY"
     gene            31859..32530
                     /locus_tag="PC592_001053"
     CDS             31859..32530
                     /locus_tag="PC592_001053"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF4055059.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPIDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVDKVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            32539..33180
                     /locus_tag="PC592_001054"
     CDS             32539..33180
                     /locus_tag="PC592_001054"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF4055060.1"
                     /translation="MKICIVLNGEIEDYEVTRGIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     KGDAKGVTLTGLEYPLDNYYMRYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            33311..33940
                     /locus_tag="PC592_001055"
     CDS             33311..33940
                     /locus_tag="PC592_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF4055061.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIDLSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERNNLLNECSLKECEYLSENGAKLFDDIENTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFVDFECPGNTGLHKGENNKLIIERNKLKNPI
                     YIGDTQGDANSAKFAGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            33995..34651
                     /locus_tag="PC592_001056"
     CDS             33995..34651
                     /locus_tag="PC592_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4055062.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVIIKRRDLMEKIADVITKKQQEILVEMEKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            35046..35768
                     /locus_tag="PC592_001057"
     CDS             35046..35768
                     /locus_tag="PC592_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012422616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055063.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIIDIMMPKMDGITLTMKLRENHNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVENKEQKVDDDDGVFAIGGLELNENTKEVSVDG
                     KHIKATPIEFKILSLLMRNAGRVFSADEIYERVWNDNAVNTDTVMVHVRNIREKIEVD
                     PKNPKYLKVVWGVGYKIEKIQR"
     gene            35737..38070
                     /locus_tag="PC592_001058"
     CDS             35737..38070
                     /locus_tag="PC592_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4055064.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVDNMYKGSYVLYHNMKEEQEGKMIQPSKLFISKETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNQNFENWESFIKESGKNLKYYLVDKESNFEFFNDNKELGALD
                     TTKNYASKEDSDENKSKNTEMSDEERQKQIKDIKENYRFYIVMNFDKDGKVNVLDSYG
                     VNQKVISQMLLSKAREDLMNTTLGGNPISYKLSPIKNVTLVYAVPKVISKGDGGEYSY
                     GNIYNNDSISSYINNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIILAILQGIVDLYPTSIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIKEYFIKNTVTGMFFVWLIKSGKVVINQIRITDLK
                     EKPNKTIAIILGINLLIIVIMCSFWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLEVNMERDLGFFNPIKDELGNIQAGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKVNSGD
                     VHLNIMNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVSIMLKNMSATEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(38349..41027)
                     /gene="mngB"
                     /locus_tag="PC592_001059"
     CDS             complement(38349..41027)
                     /gene="mngB"
                     /locus_tag="PC592_001059"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF4055065.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRKKLAIGPWYTQTDQLVISGESIVR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDTIGKLKVKSSTNNVYFPNG
                     FDQAPIRKNLPDILKKANKIDTENEYEISDIENYVDSVRNERNEFTELKGEFVNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLILKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDFHMRLISTQIKNNNEEITLTVFNGL
                     PEARNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITDYILTQTIKLNPSKKIYI
                     PKTVYRAKIALSVKNIPPMGYTQLIVELDTKNKCEIKTSSCKKIENKYYKITANKNGS
                     VEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNVQEE
                     MTLKYSLTIPASLEERTIGKVSVKMPVTMKITLEPKEQIIKFNINIKNDQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTALEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQKGVALITGCVREYQIVGANLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFNFGLYIYNNKFDKSNIANTAKRFLTPIQIYEYADFLNGRLIFVFNDEKQ
                     IYENEYSFMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDSKGSLNINKNINAAYN
                     AMLDEIYDNTNKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(41101..42207)
                     /locus_tag="PC592_001060"
     CDS             complement(41101..42207)
                     /locus_tag="PC592_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF4055066.1"
                     /translation="MSKKNNSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPSMGAGFIGGL
                     IASNTNAGFLGAVTAGFFAGYICKFLKKKIKISGSAAGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGSMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSRFSKTLSETGKGNIVMGIIGITEGAI
                     PFTLKNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISVGSGWAYLVGAIF
                     GALVIAILSTILVDFNEDETAENTEFDEIELDIM"
     gene            complement(42322..42630)
                     /locus_tag="PC592_001061"
     CDS             complement(42322..42630)
                     /locus_tag="PC592_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF4055067.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHKIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGVALKKPEAVLTKCIETIS
                     "
     gene            complement(42633..43085)
                     /locus_tag="PC592_001062"
     CDS             complement(42633..43085)
                     /locus_tag="PC592_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055068.1"
                     /translation="MVLQEKNIFIDKDLKSKEEVLNFIADSAYILGITTNKDALLKDL
                     LKRESEFPTGIRDGFAIPHTKSANVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HENEGNIHLKTLSKLATCLMEDDFISEVKNASDASHLVKYITNKMKEE"
     gene            43320..45248
                     /locus_tag="PC592_001063"
     CDS             43320..45248
                     /locus_tag="PC592_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4055069.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSINE
                     TLEKNGAIIKIKKGEGYYIDILNLALYQHYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQKIVLSEINKFNINFLDFNLK
                     NFIIHLSITISRILGGYCLDNVLDVVLTDFQSNTAVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRADTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEISLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSRIYSNLLDNFFDKNLF
                     IVNPKIKEKDELIKLMCNKLTQSEIVIPSFTESVFYRESLSSTNIDDFLAIPHPMELS
                     SIKTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDSFLSIIKSII"
     gene            complement(45507..46268)
                     /locus_tag="PC592_001064"
     CDS             complement(45507..46268)
                     /locus_tag="PC592_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4055070.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKKHHNKLLVKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIRENYGKDIIVASNKKFKNMSK
                     QDYEDWQNLSIEIISKLKKAFKTGDASSELAQEVARLHHKWLSYTWSTYSKEAHASLA
                     QMYVCDERFTSYYDKEQPGLTKFLRDAIVVYTRDN"
     gene            46487..46963
                     /locus_tag="PC592_001065"
     CDS             46487..46963
                     /locus_tag="PC592_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF4055071.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDVIYKVFSKNGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            47061..47213
                     /locus_tag="PC592_001066"
     CDS             47061..47213
                     /locus_tag="PC592_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HDF4055072.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(47373..47561)
                     /locus_tag="PC592_001067"
     CDS             complement(47373..47561)
                     /locus_tag="PC592_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDF4055073.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            47922..48272
                     /locus_tag="PC592_001068"
     CDS             47922..48272
                     /locus_tag="PC592_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF4055074.1"
                     /translation="MSAKVTNQYGSIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            48291..49934
                     /locus_tag="PC592_001069"
     CDS             48291..49934
                     /locus_tag="PC592_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDF4055075.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKDLVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVETDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGDFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGNNIEIKNADLDTNI
                     STSMDFAKSTISTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKDINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALSSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            50015..52072
                     /gene="recG"
                     /locus_tag="PC592_001070"
     CDS             50015..52072
                     /gene="recG"
                     /locus_tag="PC592_001070"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDF4055076.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDSEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKDLIIQEYMPQRIIDKYRLCSIDFAVRNIHSPNSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIINALPFKLTKAQNRALGEIIQDMDSEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQVKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGVNPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETLAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMGLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            52131..52685
                     /gene="rsmD"
                     /locus_tag="PC592_001071"
     CDS             52131..52685
                     /gene="rsmD"
                     /locus_tag="PC592_001071"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDF4055077.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKACTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            52687..53184
                     /gene="coaD"
                     /locus_tag="PC592_001072"
     CDS             52687..53184
                     /gene="coaD"
                     /locus_tag="PC592_001072"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDF4055078.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            53188..53712
                     /locus_tag="PC592_001073"
     CDS             53188..53712
                     /locus_tag="PC592_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055079.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLKEIL
                     EEVKRDKAELRPKK"
     gene            54141..55433
                     /locus_tag="PC592_001074"
     CDS             54141..55433
                     /locus_tag="PC592_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF4055080.1"
                     /translation="MEGVKVGMLKKLCSLAMVAIMTTTLITGCTSGNGKDSKKDGEKE
                     KLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISAGEGPDV
                     GYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAANPGVLY
                     YNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFGNLNWNW
                     YPYLWQAGGDIFNNDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEMIESVFG
                     PGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSSAKNKEL
                     AYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKDVYRPLVVGPHG
                     VEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            55531..56448
                     /locus_tag="PC592_001075"
     CDS             55531..56448
                     /locus_tag="PC592_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF4055081.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVTFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTIVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGAIWSLQVFDLVYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            56464..57273
                     /locus_tag="PC592_001076"
     CDS             56464..57273
                     /locus_tag="PC592_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF4055082.1"
                     /translation="MKTTRRILSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFLNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            57330..57503
                     /locus_tag="PC592_001077"
     CDS             57330..57503
                     /locus_tag="PC592_001077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055083.1"
                     /translation="MEISYVLKDCTFKHNKYSVIETETWEDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTID"
BASE COUNT        22529 a         6239 c        10018 g        18971 t
ORIGIN      
        1 tacaataata aagtaaatta aatcaatata ttattataaa aaatttactt atattaaata
       61 atatgtttta tattaactta gataataaaa attttctgga atttttatta ttatacgtga
      121 taaaaatagt tatgatcata taattcagaa aataaaattt aggggtatcc cttttggaag
      181 aattatttaa caataattat ggaagtaact ttcaaggttg gcaaattatt atggtaaata
      241 tacattataa gcattataat gatttattgt taaacatatt attttaaata taggatttat
      301 ttactttatc catatacggc tatataataa atatataaca cagagatgat aatgtgtgtt
      361 tagcacaatt aaatcaaatg agatatttga acaaagaata gtataaaatt tttaaagaaa
      421 tatgttgtat gagtaataat ctacataaca ttgtattata taatattcga aagtattact
      481 tctaagaaaa gagatttcta aagtataaaa ttaaatacta gaattgtaaa gttaatgata
      541 actacaagtt attacaagct tgtgttagtc agttagtatt agttgttaat agaagtatat
      601 ccattttttt atttaattaa aaggttaaat gtggaaaatg tcgagatagg attacttcaa
      661 atatacaatt tacaacaaac ataataaatt tagagtgtgt aaagatttat tttttaaagg
      721 ggaaatatga aagcatcaat tttaatcaca ttaatagaaa agacaagcct cattgtagta
      781 ctatttcttc taataacaaa gttaaaaata tttaagcaga tatttcaaaa agaagaatat
      841 agctttaatg atttggtctg tatagcatta gtttttactt ttttagccat atttggaact
      901 tacagtggta taaattatat ggggtcaata gtaaacacta gaataatatc tatagtatca
      961 ggaggcattt tatttggtcc aatggtaggt attacagcag gagttttttc ggggattcat
     1021 agatatttta tggatattgg agggataaca tctgttccgt gtcttttatc aagtatacta
     1081 gcaggtgtat tatcaggatt tctatataag aggataccaa agcaacatag agtaatgtat
     1141 ggtatattgg taggcatgat ttctgaaagt tttactatac tacttatata cttaatatca
     1201 tatccacatt ctttagcaat tcaaataatt ggtggaatat atttaccttt aatagttggg
     1261 cagattggaa taggatttgt tatatctata gtagagggga ttgagaaaga taaaaaggat
     1321 atagaagcga gaaataaagc agaaataaaa gcacttcaaa gacaaattaa tccacatttt
     1381 ttgtttaatt ccctgaacac aatagcttca tttataagat ttagtccaga taaggctaga
     1441 gagttaataa taaatttatc aacttatcta agatataatc ttgaatatag tgataattta
     1501 attgatataa ataaagagat tgaacaggtt aaatcttttg tagagataga aaaggctaga
     1561 tttggagagt tgctaacagt atcttatgat atagaagatg taaatataaa gattccaagt
     1621 ttaattatac agccactagt ggaaaatgca ataatacatg gtattttaga aagtggtaga
     1681 gctggtgcag tgaaaatatc cataaaaaag ttgccatatt cattagaaaa tactgtgaga
     1741 atatcaatag aggataatgg tataggcata agtgaggaaa ttataaataa tgtatatcaa
     1801 gacaatatgc cagaaaataa aattgggctt tataatgtac atttaaggct taaactgatg
     1861 tatggaagag ggcttaatat aagaagaata gataatggga ctttgatagt attttatgta
     1921 aaggagtaga agtatgagag ctataatagt ggaagacgag tttccagcaa gaaaggaatt
     1981 gagatatttt attgaaaata aaagtagtat cgaggtagta agtgaattta ccaatggtat
     2041 agaggtatta gactttattc aggaaaataa aatagatgta atttttttag atataaatat
     2101 acctcatctt gatggaatgc tacttgcaaa aacattaaat cagtttaaat caagacctaa
     2161 aattgttttt ataacagcat atgaaaatta tgcagtagat gctttttctt tggacgtatt
     2221 tgattatata ttgaagccat attctgaaga gcgaattatt tctatgctga ataaattaga
     2281 aaaaagtgag aggagtgata ttgaactgtc tagtggtaat agtaatttat acaaatataa
     2341 aaaagaaaca gtaaatcagg atatagaaga aataacacat aaaattagcc tttggaaagg
     2401 tgataaattg gttgtaatag atattgatga tatatattat tgtgaagcta atgaaaggca
     2461 gacattcata tatactgaga aagaaaagtt tatattaaaa gaaggcatat cagaagtcga
     2521 aaatcttata aatgataaaa cgttttttag aacacatagg tcttatatcg taaacttaac
     2581 aaaagtaaaa gaaattatac cctggtttaa taatacatac atattgaaat taaaaaataa
     2641 tgactatgaa gtaactgtca gtagaagtaa agtaaaagaa tttaggttgt taatgcatat
     2701 ataaagtcat ttcatgtact taaatatgca cttaatgtaa ttaatattta tattagcata
     2761 aaaaagtatt actatttgaa ctggaaatag ttttcttaaa ctcataaaaa tttataaagc
     2821 aattatataa aaactaaggg gatgaattta tggtaagttt tttaggttca atagtggtac
     2881 ttatagtagg ttattttatc tatggtactt ttgtagaaaa ggtttttgga atcaatgaca
     2941 aaaaccaaac tccagctata gcctgtagag atggagtaga ttatgtgcca atgaaatgga
     3001 agagaatctt tttaattcag tttctaaata tagcagggtt aggtcctata tttggagcta
     3061 tacaaggggc gttatttgga ccatcagcat ttttatggat tgtatttgga acaatctttg
     3121 caggtggagt acacgatttt gcttcaggat atttatcaat gaagaacaaa ggtacatctg
     3181 catcagagtt ggtaggtatt tatctaggaa atggtgcaaa aatagcaatg agaatattta
     3241 gtgttattct tttagtattg gttggagttg tatttgtaac aggtccagca ggattgttaa
     3301 agacattgac aggtgtaaac gcacaaatat gggttggagt aataatactt tattatatta
     3361 tggctactgt tttaccaata gataaattga ttggaaaaat atatccttta tttggagcag
     3421 cattattaat tatggcagta ggtgtagctg gaggattaat aataaaggga tataacatac
     3481 caaatataaa tttacaaaat atgaatccaa atggaacacc tttattccca tatttattta
     3541 taacaatagc atgtggagca atatcaggtt ttcatgcaac acaatcacca cttatggcga
     3601 gatgtgttga aaaagagagt gaggcaagac cagtatttta tgggtcaatg gttgcagaag
     3661 gtataatagc tttagtttgg gcagcagcag ccatgtcata tttccatggt atacctcaac
     3721 ttaatgtaat atttaatgat ggtggtgcag caacagtagt aaacacagta tctgttggat
     3781 taatgggtcc tattggagga gctttagcta tacttggagt tgtggcatgt cctataactt
     3841 ctggggatac agcatttaga agtgctaggc taacaatagc agatgcaatg aattataatc
     3901 aagatgcagt aaaaaataga tttttaatag ctttaccatt gttcgcggtt ggcgttgctc
     3961 ttacatttat agattttaat ataatttgga gatatttctc ttgggcaaat caaacacttg
     4021 caatgataat gttgtggact ggttctgcat atttagttaa agcaaataaa aaccattata
     4081 taactacatt accagcactt tttatgactg tagtaacatt tagttatata atgcaagcaa
     4141 aagaaggatt tagacttcca gttaatatat ctaatggaat aggtgttatt gtagcaataa
     4201 ttcttggtct tttattcttt aaaaaagcga aacatattaa ggaacaaaat aatcataaat
     4261 tggcaagtta gtaaaataat aactataaaa attaaaaatt tatatttaaa ctatgttcaa
     4321 agaagaggct gtctcaagat agagataagt ctctttttca ttgtgaaatt ataaaaaata
     4381 tatttgactt tatacaaaaa agaggattta atgaactaaa aaatttattt tgagacattc
     4441 cattttttga atcaaatctt atttttattg tatgtttaat ttacttttcc acatactatt
     4501 tttatgatat aaatattaaa attagaggtg ttaaaaatgg atactaaaaa gtataaagat
     4561 aaattattga aagaaagaga aagtttaact aatttagtag aggatatgaa agataatact
     4621 ttatttggag atacgactaa acatacaagc gaaaagtatt catcaggaga attatctagt
     4681 tatgataatc atataggaga catgggaaca gatttatata tgcaaaatat gcaaaacagt
     4741 ctaataaatc atgaagaggg aagattatat caaatagatt tagcattatc taaaatagag
     4801 aatggaacat atgggacttg tgacttatgt cataatcaaa tagatttaga aagattggat
     4861 atattgccag atacaagttt atgtaatgat tgtgcaaaga aagaaaataa tttattaggt
     4921 gatgcaatgc aaaatcctga tgtagaagat tctaattttt attcagaaga cctaacaaat
     4981 ttaactgatt taaataagaa tggaatatta agagattaga aaactgaatc atatattgtt
     5041 agaatgaatt agaaaagagg taatgacatg aagaaatcta tatggggtat atgtatatgt
     5101 ttattatcta tagtaggtgt atatacatat aatcataata cacataatca agatgactta
     5161 aaagaagctt atagtttgag tgaaaataaa attagtgatt atgaagatgt aataattaaa
     5221 aagggaagtg atgatgaaaa ggtcatagct ctaacgtttg atgatggtcc agatgaggta
     5281 ttcacaccac aagtacttga tatactaaaa aagaataatg tcaaagcaac tttttttgta
     5341 gttggagaaa aagtagaata taacaaagaa ttattaaaaa gacagtatac tgaaggacat
     5401 gagataggaa atcatacatt tacacatata aatgttgcaa agaatagcta tgataaggta
     5461 gaaaaagaaa taacagatac acaaaatgct gtaaagaatg taatcggagt agaaccaaaa
     5521 atatttagac ctccatatag agcaatgagt aagagtgttt gtgatattat agtttctaaa
     5581 aagatgaata taattctctg gtcaaaccta gaccctagag attggtctaa tcctggagta
     5641 ggcaatatta taaatactat tcttacaaaa gttcaaaatg gtaatataat acttttacat
     5701 gattataata atagaagaaa tgataagtca caaactatac aagctttaga agtagtaata
     5761 cctaagctaa aagaaaaagg gtataagttt gtaacaatat cagagcttat acaacattta
     5821 gataaaaata aacaagtaca aaaataaaaa ataattatta aaatattaat gatgcttgta
     5881 ttttaaattt ataagcatca ttaatatttt aagatagttg ctctttagag catttttttt
     5941 gtataataat aatagtgtgt ttcaaataaa attgtttttt aaataattta tagggggaaa
     6001 aatcattgct atatatatta ataataattc tactcatagg cttagaccaa ctgtctaaaa
     6061 tgtgggtatt gaataatttg gtagatgtat caacaatacc aataataaat aatgtatttc
     6121 atttaactta tgtggaaaat agaggtgcag catttggatt attacaaaat aatcaatgga
     6181 tatttataat tgttgcatta cttgcaacag tatttgggtt atactatctt aatacaagaa
     6241 aagtacatat atctggaaaa ttgggaatta tattaattat atctggtgca ttgggaaatc
     6301 taattgatag agtacgatta ggttttgtag tagattactt cgactttaga attatatggg
     6361 aatatgtatt caatgtagct gatgtatttg tagttgtagg aactgtgttt ttatgtatat
     6421 atgttttatt ttttgaaagt aaaagtaggt gatttaatgt atgaagtaaa agagttttta
     6481 gtacttgaag aggaagaaga agttagactt gatatttatc tagcagaaca attaggtgat
     6541 atgtcaagaa gttatataca aaaaattata aaagatggaa aagtaaaggt taataataaa
     6601 atagaaaagg ctaaatatct agttaaagag gaagataata ttgttataga gataccagaa
     6661 cctaaagtat tagaagttgt acctcaagat attccaatag acattgtata tgaagatgat
     6721 gatgttttaa taataaataa acctcaggat atggttgtac atcctgctcc tggaaactat
     6781 gaaaatacgc tggtaaatgg gattttatat cattgtaaag ataagttgtc atcaataaat
     6841 ggagttatta gacctggtat agttcataga atagacaaag atacttctgg tcttcttatg
     6901 atagctaaga ataattatgc acataatttt ctagcagaac aattaaaaga acatactata
     6961 actagagagt atgaatttat atgctatggt gtggttaaag aaaataaaat aactgtggat
     7021 aaacctatag ggagaaatcc taaggataga ttaaaaatgg ctgtagtaaa agatggaaaa
     7081 aatgcaatca ctcattttga agttgtagaa agatttgata aatttacaca tatgagagct
     7141 aagcttgaaa ctggtagaac tcatcaaata agagttcatg ctttgtctat aaatcaccca
     7201 cttttaggtg attatgtata tggtccaaaa gaaactaaat ttaaattaaa aggacaaact
     7261 ttgcatgcta agaagttggg atttatacat cctactacta aggaatatat cgaatttaat
     7321 tcagaattac ctgagtattt taaggaagtt attaaaaaga taaaataatc atttgtataa
     7381 tacttataaa tcattttttg tttttatgta agtaaataaa tttagtgaaa tttaaataaa
     7441 atatcttata ttaaagtatt ttgtttaaaa aagcttgaaa aatttgaaat ataaatatat
     7501 aatttgaatt gatagattaa aaaattatct ttaaacgata cagagatatc gtaagacaat
     7561 tgctaaatta cactgtatat tttttatata agagcttctt gtcttgtgat gagaagtttt
     7621 ttgttgttta aattgaaatt ttaagtaaaa ataaatttat aaaaatttaa aagaaaggag
     7681 tagatttgtc aaatagatat attatatctt tgacaataat tatgatatgg tagaaaaagc
     7741 tcaattaatg gatgaaaagg caatagcaag agcaattact agaataagtc atgaaataat
     7801 tgaaagaaat aaaggtgtag aaaatctagt tttagttgga ataaaaacta gaggtgtacc
     7861 aattgcaaat agaatttcta agaaaataga acagatagaa ggaacaaaag tagacacagg
     7921 agatattgat gtgactttgt atagagatga tttggaaaaa attgatgtcg aacctgtagt
     7981 taaaggaact tatttagatt ttaatgtaaa tgataagaca gtagttttag ttgatgatgt
     8041 tttatatact ggaagaactg ttagagcttc actagatgct attatagata taggaagacc
     8101 taaatcaata caattagcag tgctagtgga cagagggcat agagagttgc ctataagagc
     8161 agattatgta ggaaaaaatg tacctacttc tagacatgaa attatatctg ttagtttatt
     8221 agaaattgat ggagaagatt cagttacaat caaagaataa taatttttaa gtattatata
     8281 aaagcttagc attgaatagt caggaaggag gataaagctt acatagattg cacaaaataa
     8341 atattataat tttatggatg tgggtcttaa tgtagtcttt attctccttt atttgagttt
     8401 tgatgtcgta aaatgtaaaa taataataaa ttatataata agtatataga ggttaaaaaa
     8461 tagaatctag ggaatgataa ttaattaaaa gatattaatt aaacagagga tttatttata
     8521 tataataatt ttggaggttt ttatgaaaaa aacgataatg tctttacaac atctattagc
     8581 catgtttgga gcgacagtat tagttcccat tttgacaggt tttaatccgt cagttgcaat
     8641 tttctgtgct ggtgttggta cattgatatt tcatttttgt acagaaggaa aagtacctgc
     8701 ctttttaggt tcaagttttg cgtttatacc agttatatta gcagctaaag aggcgtatgg
     8761 tggagattta gcgtatgctc aaggtggtat aatagttgca ggattaattt atattataat
     8821 gtcgattata gtaaaaatag ttggagtaaa taaaataaaa ttatattttc ctgcacaagt
     8881 tacaggagct atgatagtag ttataggatt aaatttattg ccaacagctt ttaatatggc
     8941 ttcagccaat tttgtaatag cattcataac tttagcaata gcaattttaa ccaataagtt
     9001 tggtagagga tttataaaac aattaggaat attaatagcc gttttttctg gatatataat
     9061 ctgtttgata ttaggattag tagatataac tacaattaca gaggcaagtt tatttgcaat
     9121 acctaacttt acagttccta agtttagttt aggagcaatt gtgattatat ctccagttgt
     9181 gttagctgta tttatggaac atatagggga tatgactact aatggtgctg tagtaggtaa
     9241 aaattttata gaaaatcccg gattaaatag aactttactt ggggatggat ttgcaactat
     9301 agttgcaggt tgtttaggag gtccagccaa tacaacttat ggtgaaaata cagcagtact
     9361 tgccataact aaaaattatg acccttcaat acttagacgt acagcaatat ttgccatatt
     9421 gcttgcatgt gtaggaaagt ttggtggatt tcttcaaagt ataccaggtt cagttatggg
     9481 tggaattagt ataatgctat tttcaatgat aacttatgta ggattaaaaa ctataagaga
     9541 tagttcttgc gtagaaagta agataaatat attgataata gcatttatat tattaatagg
     9601 tcttggaaca acatatttgt ctaataaagg tatttctatt ggaatcccta taacaagtac
     9661 agtaaagata actggcctta gtctagctgc aattgttgga attgtattaa acagaatttt
     9721 aaataatcag gattttaaag ttgaagaata ataaattgta tattgaataa tttaaattag
     9781 ttaattttct atagacattt gtaattaatg ttgatataat gattaaaaat aaatgaaaga
     9841 aagggcaagg taactgggac aatgagaata taatctattt tttataatta aagtattgta
     9901 atttttgaaa agcctatttt ggtggcttta tttgcgatgc ttaaattaag gagagtagat
     9961 tatagtctat acgtttattt gttatgccta tttatagaat ctctccttat atttaagagt
    10021 gttaaggagg gattttttat gttattagta aaagtagaga acttaaaaaa atattatgca
    10081 gacaaattaa ttttagatat agataaactt gaaatattag aaaacgacaa aatagggcta
    10141 gttggttcaa atggtcaagg aaaaacaaca ttattaaaag caatattggg tgaaatagaa
    10201 attgatgaag gatatattta ccttacagaa agttattcct atataagtca gagtgaaaat
    10261 aatattgaaa tatgtagtga tagtaaagag aagagtcttt taaatgctcc agatagattt
    10321 gaagagtact tatcaggagg ggaaaaagtt aagttaaaaa tagcagatgc actgagcaat
    10381 aaaaaaaata tcataatagc tgatgagccg acttcaaact tagataaaaa aagtattgga
    10441 gttttggaag agatgtttaa aaggcatgag ggagcattat tattaatatc tcatgataga
    10501 cgttttctgg atgagttgtg tacaactata ttagaactag aagatggaaa actaaaagcc
    10561 tacaaaggca attacactga ttatttaatg caaaaagatg aagaagtaaa aagagcttat
    10621 tttgagtatc aggaatatgt taaagagaaa aaaaggcttg aaaaagctct tttacataaa
    10681 aaatctttaa gtgatggcat aagaaaaaca ccaaaaagaa tgggtaattc agaagctaga
    10741 ttgcacaaaa tggggggtca gactaataag aaaaagttgg actcaaatgt gaaggctata
    10801 aaaagtagaa ttgataaact tgaggtaaaa aataaaccta aagcttctat agaaatgaag
    10861 attaagattc aaaatggtat ggagataatt agcaaaaatc tagtagagat aaaggatatg
    10921 actctaaaat taggaaataa actgctatta gataatgttt cttttaagat aaaaagaggt
    10981 aaaaagatag cattattagg tgataatggg tgtggaaaaa gtactatgat aaaagaaata
    11041 ttgaataata aaaatgacaa tataaaaata aataacaaag taaaggtagg ttattttgac
    11101 caacatcaaa gcttattaga tgaggcaaag agtgttttat acaatactaa agttaatagt
    11161 tcatttgatg aatcttttat aaggacaaac ttaaacctgt ttggatttaa aggagatgat
    11221 gtctacaaaa aagtaaaagt acttagtggt ggagaaaagg taaaaatagc actatgtaaa
    11281 ataatattgg aagataataa ttttttaata tttgatgaac caacaaatta cttagatata
    11341 aaatctatgg aagcactaga aaaggcactg ataaatactg ataaaactat gcttatagta
    11401 tctcatgata gagtatttgt atcacatatt tgcaactata ttatagagat aaaagacact
    11461 aaaataaggg agtttgattg taattatgat gaatatataa ttaatagaaa caaaaaaaat
    11521 cctagtagag aaagtaagat taaaaaagaa aatcttctag tattagaaaa tagacttata
    11581 actattgtat ctatgttatc tatagaaaag gatggtctaa aaaaagaact ttatgaatca
    11641 gaatacaatg aactactaaa acaaatcaat aaattaaaaa atagctttta gtattaactt
    11701 tttaattata tctatataag aagactaaaa atacttatta ggaatataag tatagttatt
    11761 agaatataaa agtgtgttga ttagaaagtg gccttattat tgtacttcat aataagacca
    11821 ctattttcat tttaaatgat aatgtgtgct tgtctaacac ttattttata tttagtgcag
    11881 aatttattca gatttaacct taagtttagc tactgtttct tcttcaggag taacataaat
    11941 agtactgtta gtctcataaa taaccatacc tggtttagaa ccactaggtt tttttacatt
    12001 ttttctttta gtataatcta caggcacctg agaagaaagt tttgacttac taaagaatgc
    12061 ggctagcatg gctccttcaa atacagtatt atcagggact tctttaccag cacactttat
    12121 tattacatga gaaccaggaa tattctttgt atgcatccat aagtcgtcgt tatcagcaag
    12181 tcttagtgta agatagtcat tttgcttgtt gtttttacca accaatattt taaatccatc
    12241 agaagacata aattcatgag gctttgtaga tggaatagta tcctttttac tgtttttctt
    12301 ttgagtcttg atatatccaa ctttagcgag ttcctctttt atatcttgta attcagctaa
    12361 attttcacaa ttttcaatac ttaaaattat attttctaag taatctattt cttccttatt
    12421 taaggaaatt tgatgagata tctcgacttt agcatgtttc attttattat actttttaaa
    12481 gtatttttga gcattttcag atggtgtcaa gtttttattt aattctattg ttacattatt
    12541 acaattttca tcatagaagt tagcaacttc aatactttcc ataccttttt ctaccatata
    12601 gatgtatgaa gtaatcaatt ctccttttat cttataaata tctgcatttt cagattctga
    12661 taattcttct tcttgttttt taagtttatt ataaagtcta tcaagtttaa cagatatgct
    12721 cttttttaaa tcagatgaac gttgattaat tctatcttta atatctttag ttctatagaa
    12781 atcttcaagt atacgagaca tactatcctt atttatatat gataaatcac taaataatgt
    12841 aaggtttata cagctgaaat caactaccct atccaccttt ttatctataa caatgcaagg
    12901 tgagtattta ttagaattta tatcattaaa taaattacaa aatactttgt gtaaagaatc
    12961 aaattgctca tcagatatat cttttatgat ggtgttttga tttatacctg ctctgtagca
    13021 aatttcttta gctataatag ggcttatacc tagaaattta gaatatatag acttaaagat
    13081 agattcttct gattcctcta ggtttttaat gaacaaatcc ttagatatag catcaagagg
    13141 gtttagtttg ttttgctctg gaggtaatga ataatcatga ccaggtaaaa cttgacgaac
    13201 tctacttata ctaaaaggga ctctttttat agaatctata attttatttt cttcaccatg
    13261 agttattatt atgttgctat gtcttcccat aatttcaatc ataatatttt taattgtctt
    13321 ttcctttagt tcatctaaag attcaacact tatttttatt attctttcaa aacctatttg
    13381 agaaatttct actatatttc caccttgtat gtattttcta agtaacatac aaaacatagg
    13441 tgcttttaga gggttttctt tttgataatt gcttgtaaga taaactctag gatttgaggc
    13501 acttgcactc aaaaccaatc taaaattttc tttattattt cttatattaa aaattacctc
    13561 atcatcttca ggctgatgta tcttatctat ttttccacct gtaagttttg atgataattc
    13621 atcgactatt gaatgtataa ctaatccatc taatgccatg tatagcaccc ctttctttga
    13681 ccaaaatgag tcagtaaatt aattatacac ataatatacg ctttgtgact agagggaatt
    13741 taaacaatag agattaatat ttaaattgta taattattta tacttattag aaaggaaact
    13801 ttatttttaa aattaataat ttaaagtaga ttaaatataa agtaaatata gtataattat
    13861 tgtgtaaagt ataagctatg aaagtatatg aactttacag aaaaaatcaa ttttaaggtt
    13921 ctatagtata taaatatgaa agaaggttga aaaaatgaga tttatcgatt taagaagtga
    13981 tactgttact atgcctactg atgaaatgag agaagctatg gcaaaggctc ctgttggaga
    14041 ttcaatcttt agagatgacc ctactgtaaa taaacttgaa gaattagcag cagctaaagt
    14101 tggaaaagag gatgctattt ttcttccaag tggaactttt ggtaatcaat tagctctatt
    14161 cacacattgt ctaagaggac aagaaataat tattggtaaa ggatatcaca ttgtaactca
    14221 tgaggttggg gcacctgctg taatagctgg agttcagctt agaactatag atgaagacga
    14281 aaatggagct cttaatcctg aacttgttga aaaggcaatc agaagagatg acatacatga
    14341 accacagaca gggcttatat gtgtagaaaa tgcatattca ggtggaactg ttgtgggtct
    14401 tgataattta agagaaatta aaaaaatagc tgagaaacat aacttgccag tacatctaga
    14461 tggagcaaga ttatttaatg cagcattaac tttgggtgta gaagctaaag aaatagcaaa
    14521 gtgttgtgat agtgttatgt tctgtgtgtc aaaaggttta gctgcaccaa tgggttctat
    14581 acttgctgga agtaaagact ttatagcaaa agctagaaga aagcaaaaag ttatgggtgg
    14641 aggaatgaga caagtaggta tagttgcagc agctggtata attgccattg aaaaaatgac
    14701 tttaagattg aatgaagacc atgaaaatgc aaaatattta gcttgtgaac taaataaaat
    14761 tgatggcatt gaagtgaaca atgttaatcc agatataagt atggtatttt ttaagatgag
    14821 tgaagatatt ataaaagagg atgttttaat aaaagaattt tttgaaagaa atataaaaat
    14881 taataaaatg gaaaatggtg aatatagatt tgtaactcat gtagatatta ctaaggaaga
    14941 tttagactat gttttaaaaa cacttaaaga attaataggt gtatgttaat agatatctac
    15001 caaaagaatt atagctggtt atcagatgtt taattaaaaa attcatagac agtttaaata
    15061 aaacatacat aaaattcata tagaaatatt attatataaa catagaaaga actagcttaa
    15121 aaacataata taattaccct aattgtaatg gcaactctcc ctcacatcct caaattatag
    15181 ttgtcattac aaaatttttc ccataaatta taagtttatg ggaatttttt tatgttataa
    15241 tagtttaagt gttaatttac gaaggagcga tacttatgaa attttggaaa ctacatggaa
    15301 taggaaatga ttttatagca atagatggaa gattcgacca gataaaccca tctgattata
    15361 ctgctttagc aaaaaaagta tgccatagaa gattttctgt aggagcggat ggattgttag
    15421 ttgtgaaaga ttcaaaagtt gcagatgtag aaatggtata ttataattct gatggttcaa
    15481 gagcagctat gtgtggaaat ggtcttagat gtttttgtaa atttgtttat gataattgta
    15541 tagtcaaaaa agaaagtttt acagtagata cattagatgg tataaaagat ataaaaataa
    15601 accttaccaa tagagaaata aactctataa gagtcaatat gggaaaagga agttttatag
    15661 ctaaggatgt tcctgtactt acaaataaag aacgttttgt gcaagaaagt ataaaggttt
    15721 tagatagtga gtttaaagtt acttctatgt tgatgggggt tcctcataca gtagttatag
    15781 tagatgagtt agatgtagag gatgtttgta aatatggaaa agagattgaa aataataaaa
    15841 tatttcctga aaaaacgaat gtaaattttg taaaggtaga agataagtat aatatacatg
    15901 tttatacttg ggaaagaggt tgtgggtata ctctaggttg tggtactggt atgactgcat
    15961 cagcaatagt gtgcaattta cttaatatgg tagaaagtag tgtaaatgta acgtctcaag
    16021 gtggaacagt taaaatagat gtaggagatt tctcttatat gacaggtcca gcagtaaaaa
    16081 tatgtgaagg tattttggag gtttaattaa tggctataag tatgactggt tttggaagag
    16141 gagaatacaa ggatgataat tattactttt tagtagagtg taaaacgata aatcataagt
    16201 attcagatat aaacatacgt cttccaagaa aaatttcatt tttagaggat aaagttagaa
    16261 atttagtgaa aaattatgta aaaagaggaa gagtagattt atacataaag tttgacttat
    16321 taggcaaaga agatgtaaac ttaaattttg atgagggatt agcatctcag tatatagaca
    16381 tactaaaaga aataaaaaac aaatttgaca ttatagatga tattagtgtt atgaatgttg
    16441 caaagtttcc tgatattgtg aaaatagaag aaaaggaaga agatgaagat ttattatggt
    16501 caatgttgaa tcaagcagtt gaagatgcat taattaaatt aagagaaatg agaagtgaag
    16561 aaggtaaaaa gttagctgaa gatattgcca tgagatgtga tttattaaaa aatcatatag
    16621 aagaaattga aaaatattca agtagtgttg tggaagatta tagagaaaaa ttgaatttga
    16681 gaataagtga attactggat gacccaagta taatagatga gaatagatta gcgcaagaag
    16741 ttgcaatata tgcagataaa agcagtataa cagaagaaat agttagattt aaaagtcata
    16801 tagggcaact taaaaatact atatttaaag acgactctat aggtagaaaa atagatttct
    16861 taatacaaga aatgaataga gagactaaca ctataggttc gaagtcgtct gatataaata
    16921 taactaattt agtagtagaa gtaaaaagcg aattagaaaa aataagggaa caaatacaaa
    16981 atatagagta agaatacaat attagaaggg gaatgcttaa atgtttgtga aaaaaggatt
    17041 attgctagtt gtatcaggac catcaggtgc aggaaaaggt actatttgca aagaactact
    17101 taaagaaaat gatacaataa aactttctgt atcagctact acaagaaaac ctagaactgg
    17161 agaagttgat ggagtaaatt atttcttcat aagtaaggaa aagtttgaag agatgataga
    17221 aaaaggtgag tttttggagt atgctcaaat ttatgataat ttttatggaa ctccaaaatc
    17281 agcaataatg gaatgtttag aaaaaggaca agatgtatta ctggagattg aaatgcaagg
    17341 agcaaaacaa ataaaagaag tttgtccaga aggagtattt atatttgtac tacctccatc
    17401 acttgaagaa ctaaaaaata gaattgttgg aaggggtaca gaaacagaag ccgaaataga
    17461 gaagagattt agctgtgcat atgaagaaat taaaatgatt aaggattatg attattttat
    17521 atttaatgaa gatgtaaaaa catctgctaa agaaatagaa ggtataatat catctgaaaa
    17581 gaataaagtt agcagatata aaaatattat aatagagaaa ttcaaggagg aattataatt
    17641 atgttaaaac catctatcaa tgaggtacta gaaaaaatag acaacagata ctatttagta
    17701 gggactgttt caaagagagc aagaaaatta attgatggag aagagccata tgtttcaaat
    17761 aaagctaagg agaagcctgt atgtgtagca actaaagaag ttgcaagtgg aaaaataaca
    17821 tatagattat tgacagaaga ggaaatagag atagaagaag ctagacacca tgctgagcaa
    17881 caccaacaaa tttcagaaga ggagtaaggt catgctaaaa gataaaactg ttgtaattgg
    17941 cataagcggc ggaatagctg catataaggc ttgtgatgtt gtaagtaagt taaaaaaact
    18001 aaatgcaaat atccatgtta taatgacaaa atcagcaaca gaatttgtta acccacttac
    18061 atttcaatca ctgagtcaaa attatgtagt agaagatatg tttgaagaac caaaaacttg
    18121 ggaagttgaa catatatcat tagcaaaaaa agcagattta tttttaatag tgccagcaag
    18181 tgcaaatgtt ataggtaaga ttgcaaatgg tatagctgac gatatgttga caactactgt
    18241 tatggcaaca aaagcacagg ttcttatagc accagctatg aatactaata tgtatgaaaa
    18301 tccaattgtt caaaaaaata tacaaacttt aaagagcttt ggatataaat ttattgaacc
    18361 agaaagcgga agacttgcat gtggagatat tggagcaggt aaactggcca atccagatat
    18421 aatagtggag gaagttttag ctaatcttac taaagaacaa gatttaaaag gtcaaagtat
    18481 gatagttaca gctggtccaa ctgtagagag tatagaccct gtaagatatt taactaatag
    18541 gtcttctggt aaaatgggat attctatagc aagagaagct atatctagag gtgctgatgt
    18601 aacactaata tcaggtccta caaatctttc tatcccacaa aatcttaaaa aatttgttca
    18661 aatagagtca gcacaagatt tgtacgaagc agtagtatca aatttaagtg aaaataaaat
    18721 agtgattcaa agtgcagcag ttgcagatta taagccaaaa acttattctg ataaaaaaat
    18781 taaaaagaag aatgatgatt tatcaataga gttaagtaga aattatgata ttgcttatga
    18841 aataggaaaa ataaaagaag ataagatact agtgggattt gcagctgaaa ctaatgacct
    18901 gatagaacat gccaaaggaa aaataaaaaa gaaaaaccta gattttattg tggcaaatga
    18961 tttaactaaa gaaggtgctg gatttagagc tgatactaat attgtaaaaa taatagatgt
    19021 agaaggaaat attactgagt atcctaaaat gaaaaaagaa gaagtagcca atgttatttt
    19081 agataaagtt aaagcgttgc ttgagaaata agaccttttt taaatatgat atttgtgtat
    19141 tttatcacag ctaaagtggc tgaaagctgc aatttaattt tagcgagtaa aaactcgcaa
    19201 atgtcagtta aattgtagtt ttcagcattt attttgtcat aaagtataaa atataattaa
    19261 tagttaatta ttaaaataaa gttaatatta ataacttgga attgtttata aattatgaaa
    19321 ttttaatgtc ttgtaaagta tattaaaata tgaacagtat attaaattta agtagaggtt
    19381 ttataatgaa aaaatatgca aaggtaatag ttagaagtaa tactatatac acagataatt
    19441 tatttacata ccaaattcct gtatttttat ctgaggtcat aagaatcgga cacagaatat
    19501 tagtaccatt tggaaaaggt aataaaccaa cagaagcctt tgtatttcaa tttacagata
    19561 gcttagatga aaaaataaaa ataaaagaaa ttattgatat attagatgaa aatccaatat
    19621 ttagaaaaga agatttagag ttggtttatt ggatgaaaaa tagatatttg tgcacttata
    19681 tagaatgtat aaatttgata tatccaaagg gatacaaact aaataattat aaagtagtcc
    19741 tattaggtga aagtttaagt ggattaaatg atattgaatt gaaggaaaaa atatcaactt
    19801 taagtgataa aaatagagaa atagtagaaa aagtgattga gagtaaaggt aaaattaagg
    19861 ttgataagtt aaaatatata ccaaacttaa atagttcttt gtacacaatg aataaaaatg
    19921 gaattataaa attatgttgg gaatataaaa atcacaaaaa tgaaaagaaa gtatgttata
    19981 tatctttgag tttggaaagt gataagattg atgattatat agagcaaaat aaaataaatg
    20041 taggaagtaa acaaaaagag atattaagtt ttcttaaaaa taatgaaaat gtagagataa
    20101 atgatttatt ggatttatta aatgcttcaa aacaaagtat aaattctcta agcaagaaaa
    20161 aactaataac cttagaattt aaggattatt atagagagcc aaaaagtatt tacaaatccg
    20221 tgttaaaaag tataaaatta aacaatgagc aacaaaaagc agttgatgaa ataaagtcga
    20281 atatgttttt agatgataaa aaaccatact taattcatgg agtaactgga agtggaaaaa
    20341 ctgaagttta catggaaata atagaatttg ctctaaatca aggcttagac agtatattct
    20401 tagtacctga gatagcatta actcctcaaa caatagatag gcttaaaagt aggtttggag
    20461 atttagttgg tgtgtttcac agcaaactat ctgaaggaga aaaacatgat gtttataagg
    20521 ctgtcaaggc aggtaaagta agagtgttaa ttggagctag gtcggcttta tttgcacctt
    20581 ttaattcttt aggcttaata ataattgatg aatgtcatga gtcatcatat aagtctgaga
    20641 agaatccaaa atttaatgct atagaagttg ctagatttat ggcattaaaa aataatataa
    20701 ctcttatttt aggttcagca acaccatcaa ttgaagagta ttatagggca aaatacggag
    20761 aatacaaact tataaatata aagagtagag caaatgacaa acctcttcca aatattgaag
    20821 tagtagacat gaaagaggag ttagataaag gaaatagaag catatttagt ttgaaattac
    20881 aaaaagaaat acgttgtgcg attgaagaaa ataatcaagt aatactgttt ttaaatagaa
    20941 gaggttatgc aaattttgta tcttgtagaa agtgtggata tgtgtttcaa tgtgaaaatt
    21001 gtgatatatc tttaacttat cataagaaaa gcaatactgg aagatgccac tattgtggat
    21061 atgagaaaga aattccaaaa gagtgtcctg aatgtaaaag tacttatgtt aagccatttg
    21121 gagttggaac tcaaaaaatc gaggaggaat taaaatatat ttttccagat ataaaaactt
    21181 tgagaatgga taaagataca acttcaaaaa aaggtgcttt agatgatata ctaaataaat
    21241 ttaaagataa aaaagcagat gtactaattg gaacacagat gctaagcaaa gggttggatt
    21301 ttgagaatgt aactttagta gggattttgt ctgcagacat gatattaaat tttccagatt
    21361 ttaaaagttt tgaaactaca tttcaattga taactcaagt ttctggaaga gctggaagag
    21421 ctgataaaga aggaaaagta gtacttcaaa cttatgatac tgaacactat gctattaagc
    21481 atgctattga atatgattat gaaggttttt atgaagatga gataaaaata agaaaagcat
    21541 ttggatattc tccttttaat aacatgttaa gtgtagttgt tagtggtgaa gatgagcgat
    21601 tggtagtaaa aaatataaaa aatatgcatg catctttaat ttatttatta gaaaaaaggg
    21661 gtataaatga tttaggattt atattaggtc caaacccatg ttcaatatca aaaataaatc
    21721 aaaattatag atggcaaata ctctttaaag acgaaaatat tgaaattaat ctcttaaagg
    21781 gtataataaa atatatatgt ataacaaaac gagatttgat atttgataag aatatcagtg
    21841 tatctataga tattaatcca aacagtgtat tataaattta ggaggaatta taatggcttt
    21901 aagacaaata gttcaaatag gagaaccagt attaagaaaa aaatcaaaaa aggttgaaaa
    21961 aattgatgaa aagataatac aattattaga tgatatggca gaaactatgt atgatgcaga
    22021 tggcgttgga ttagctgcac cacaagttgg aatcttaaaa agagtagtag taatagatat
    22081 tggagaagag cttatagaac ttataaatcc tgaaataata gaaacatctg gggagcaaat
    22141 agatgaggaa ggatgcttaa gtgttgttgg agaagcggga aatgttagaa gaccaaatta
    22201 tgtaaaggtt agagctttaa atagaaatgg tgaaacaata gagttagagg gagaagaact
    22261 tttagctaga gcattttgtc atgaactaga ccacttagat ggaattttat ttgttgacaa
    22321 aatagaaaag tagtaggagt tgatttaatg aaaatagtat ttatgggaac tcctgatata
    22381 gcagttccat gtttacaaaa aataatagat gagaagtatg aaatattggg tgttgtaact
    22441 caaccagata aaccaaaagg aagaggtaaa aaactgggta tgagtccagt aaaagaactg
    22501 gcaattgaaa ataatatacc tgtatatcaa ccagtaaagg ctagagataa agaatttata
    22561 gatacaatta aatctttaaa tccagatgta atagtagttg tagcttttgg acagatactt
    22621 ccaaaaggaa tattagagat tcctaagttt ggatgtataa atgttcatgt ttctttactt
    22681 ccaaaatata gaggtgcggc acctataaat tgggtaataa taaatggtga agaaaagact
    22741 ggtgttacaa ctatgtatat ggatgaaggt ctagatactg gagatatgat actaaagaca
    22801 gaagtaaacc ttgatgaaaa tataacagca ggagaacttc atgataaaat gatgaatata
    22861 ggagcagaga ctttaaaaga aacattaaga ttaattgaag aaggaaatgc tccaagagaa
    22921 gtacaaaatc atgaagaatt ttcatatgcc ccaataatga ataaatcatt aggtaacata
    22981 gacttttcaa aaagtgctag ggaaatacac aatttagtta gaggggtaaa tccatggcca
    23041 agtgcttata ctacctataa tgatgtcata atgaaagttt ggaaaactaa agtgttagat
    23101 gagaaaagta caaaagatgc aggtacaata attgatgtaa gcaaagatgg aataaaagta
    23161 agtactatag ataatgtact tttaattgaa gaaattcaga tgccgaataa aaaaagaatg
    23221 ttggttggtg aatatataaa agggaatact atagaaactg gtttagtatt gggttaggtg
    23281 aaaagtatga cagatataaa gaagtattta acaagtgttg ggattttgat tttaatatta
    23341 gggcttttga taggagttgt taattttttt ataataagtt taactcaaat attttcctta
    23401 ataataaata ttataataat atcactaata cttataatac tatgttcaac agcagttact
    23461 tatagagtaa ttaaaggaaa gaatattaac tcaaatataa tgaaaataaa ttttaatatt
    23521 gttagtggat tatttcctat tatatctttt attgcatcat catttggtat gtcaaaaagt
    23581 gagattagaa gaatatatat aaagttaaat aatgaatata tatacagtaa taaatataat
    23641 tttaatccag aggatataat aattttaata cctcattgta ttcaagagaa tagttgtaaa
    23701 ttaaaagtta ctaatgatat agataattgt gaagaatgtg gaagatgcaa cgtaggagaa
    23761 ttaattaagc taaaggaaaa aactaatgta aaaatatttg tagctacagg aggaacacta
    23821 gctagaaaaa ttataataga caataaacct aaagctgttg tagccgttgc atgtgaaaga
    23881 gatttgacat ctggaataca agatattaaa aaaattcctg ttttaggtgt atttaacaaa
    23941 agacctaatg gaccttgtgt aaatactaat gtagatatga tagacattga aaaggctata
    24001 gaatttttaa caggaaaaaa tatattagct tgtaattaaa ctgtttttaa gttaagtgaa
    24061 tattaagagg atgtataata aaaatatatt ttaggagagt gttatttatg taccctgtat
    24121 atggcggttt ttggggattt gacccaacaa tggttgtatt aattccagct atattactta
    24181 ctatatatgc acaatttaaa gtgagttcaa caacaaacaa gtatttaaga gtaaatacac
    24241 gtcgaggata tactggagag caaacagcaa gaagagtact tgattcaaat ggtttgtatg
    24301 atgtaaagat agaaatggtt agaggacatc taagtgacca ttatgaccca agaagaaagg
    24361 ctgtaaggtt gtcagaagat gtatattatg gaacatctat aacttctgtt gcagtagctg
    24421 cacatgagtg tggtcatgcc atacaacatg ctaaaggtta tgcacctctt caaataagaa
    24481 gtagtttagt accagtagtg aattttgctt caagtatatc ttggttttta atatttctag
    24541 gatttattat ggctggtcca tttttaaaaa ttggtatact attgttttcg gcttcagtgt
    24601 tattccaaat aataacattg cctgtagaat ttaatgcttc aagtagagca atagttcaac
    24661 ttggaaattt aggtattata gatgagagtg agtcaagaca aagtagaaga gtgctttcag
    24721 cagcagcttt aacatatgtt gcagcagcat tggtttcaat acttcaatta cttagattgt
    24781 tactaatagc tcaaagaaga aatgactaaa agtaaagtgg gttgtttaga aacaaccctt
    24841 ttttatgttt aataaaaggg agaaatttat atggatgcaa gagaagttgg atttaaggta
    24901 ttatgtgata tagaaaaaaa taacaattat tcaaatattg caataaataa gcattttaaa
    24961 aatttagaaa taagtgacat tgatagaggg cttgcaacag aattaattta tggagtaata
    25021 gaaaataaat attatttaga ttatataatc aataaacttt caaaaataaa ggtaaaaaaa
    25081 atgtcaactt atgttaaaat ctttttaaga atgggaacat atcagatttt gtttttagat
    25141 agtatatctg attatgcagc agttaatgaa actgtgaaat tatctaagaa atatgataaa
    25201 aaatcttctg gtttcataaa tgctattctt agaaatgaaa taagagctaa agagactata
    25261 atggacataa ctgaggaaga tagtgtaaaa tacctatcta taaagtattc ctataactct
    25321 tggattataa aaaactggat agataaattt ggacaagaat ttgctgaaga tttattggaa
    25381 gcgaatagtg aaaagcctag tatctatata agaacgaata tgcttaaaat aagtcgagaa
    25441 gaacttattg aaaaattaag tgaaatgggt attgtatgtt taaaagttcc tatggtagaa
    25501 gaagctatta aagtcgaaaa aatgaaaaat atagaaaaaa atgaattatt taaggctggt
    25561 ttatttacaa ttcaagatat aagttctatg atagtaggga aagtaattaa tccaaaagaa
    25621 gactcatttg ttttggacgt atgtagtgct cctggaggaa aatctactca cttagccact
    25681 ttaatgaaca acactggtca agtagtagct agagatattt ttgagcataa actaaaactt
    25741 ataaaatcta ctgtaaacag attgggactt aaaaatgtat gtgtagaaag atttgatgct
    25801 tctgagattg atgaaaatag tataagtaaa tttgattatg ttttagcaga tgttccttgc
    25861 tctggtcttg gtataataag acgtaaacca gagattaaat ataagaaaga agaagagtta
    25921 aaagacatca cttctataca aaagaaaatt ttagaaaatg catccagata tgtcaaagtt
    25981 ggtggaactt tagtatatag tacatgtaca attcaagatg atgagaatat aaatatagtt
    26041 gcttcttttg ttgaagaaaa tcacaacttt gaatttgatt cgattgatac agtaaatgta
    26101 gatttagata atcaagataa aggatattta aagatatatc ctaatattca tggtatagat
    26161 ggttttttca tagcaaaatt aaagagaata aggtagtgag agaatggaaa agaaaaagat
    26221 agtattaaaa aattttactg aagatgaact taaagaattt atgaaaacta tagatgaaaa
    26281 gccctttaga ggaagccaaa tattctcttg gatatataag ggtgcaaaaa cttttgagga
    26341 tatgaataat ataccaaaaa gtttgagaaa taaattagaa gaaatttcat gtataggtca
    26401 tatagatata gaattaaagt tagaatctaa ggtagataat acaaaaaaat atttgttttt
    26461 attagatgat ggaaatataa tagaaactgt gatgatggat tatgatagta gagttactgt
    26521 ctgtgtctct aatcaagtag gttgtaggat gggatgtaat ttttgtgcat ctacaatgga
    26581 tgggttaatt agaaacctag agccatggga gattttagac caagttatta aaattcaaga
    26641 agatactggt aagagggtat caaatcttgt attgatggga agtggtgaac cacttgataa
    26701 ctttgaaaat acaaaacaat ttttaaaaat aattaacgaa aaaaatggtc ttaatatagg
    26761 gtatagacat ataactcttt caacttgtgg gatagtacct aaaatgtatg agttggcaga
    26821 tttagaaata gctataaatt tagctttatc acttcattca ccatatgatg aagaacgaag
    26881 aaaaattatg cctgtagcaa atgcttattc tattaaagaa atattagatg catgtagata
    26941 ttatataaaa aagacaaata gaagggttac atttgaatat tctcttataa aaggggtaaa
    27001 tgactcagaa aaagaagcaa aggcattagc taagctccta aaaggtatgc tatgtcatgt
    27061 aaatttaatt ccaataaata aagttgaaga aagagaatac gaaaagccag ataaagcatt
    27121 tatttataaa tttagggata gtttagagaa aaacaatata cctgccacag ttaggatgtc
    27181 tatgggttct gatattagtg gagcttgtgg gcaattgaga agaaaataca agtaatttgt
    27241 aaggaggaag tcgtatggtt tatagttgtg cctcccatat aggaaaaata agaaaaaaca
    27301 atgaagacta ttgtgaggga gaagttatag atacagaaca tggtccaata ggaatatttg
    27361 ccatagctga tggaatgggt ggacataaaa aaggtgaagt cgccagtaaa ttagcagtag
    27421 aaaatataat tgattttcta aaagaaaact tattacaaca tgataatgta aaaatagact
    27481 atatagatga tatattaaaa caggcttata ataatgtaaa ctcaattgtg cacaaaaaat
    27541 ctatggaaga tatagaattt gaaggaatgg gaactacatt agttacagct atagtgtata
    27601 ataatgtctt atatgtggca aatgttggag atagcagatg ttatttgtta acagatgaaa
    27661 aatttgataa aataactata gaccattccg tggttgaaga acttatgatg gctcatgtca
    27721 ttacagaaga agaggcaaga agacatccac agaggaatag aataactaga gcaattggga
    27781 cagatgatat ggttgttgta gatattttta agaaagaaat caaaaaaagt gatataatac
    27841 ttcttgcgac agatggatta actgggttta ttgatgatga agatataaga gatttaatat
    27901 tagattatga atatgagaga actagtaata taagtgaaga attgataagt atggccaatg
    27961 atgtttctgg taaagataat gtttcggtta tagtgataaa agtataatta ggacggtgat
    28021 attgtgggag atacaatttt aggaaatcga tatgaaatca tcaggaagat tggtgatgga
    28081 ggaatggcct ttgtatatga ggctaaagac agattattaa acaggactgt tgcacttaaa
    28141 gtacttagac ctgaatttgt agatgatgat gaatttttaa caaagtttaa aagagaggca
    28201 gaggcagtag caagtctttc ccatccaaat atagtaaatg tttatgatgt tggtgaagat
    28261 ggaaaggttc actacattgt aatggagttt gtagatggaa aaaatctaaa agagattata
    28321 caagatgaag gtatattaga tgaatatact gcattagata taacaaaaca aatagctatg
    28381 gcacttagtg ccgcgcacaa aaaggggatt atacatagag atataaaacc tcataatatc
    28441 ctcatatcga atgaaggaag agtagtaaaa gtggctgact ttggtatagc caaagctgtt
    28501 tcaaattcaa caatgactaa tattggtagt ataataggtt cagtgcatta tttttcgcca
    28561 gaacaagcta aaggtaaatt tgtaactaat aatgctgatt tgtattctct aggtatagtt
    28621 ttatatgaaa tgttgatagg aaaagttcca tttaggggag acagtccaat ttctatagca
    28681 cttcaacaca ttaatgatga tatagacttt acatcagaag aaaaagttag gattcctcaa
    28741 agtgtaagaa ctacaataaa aaagcttaca gaaaaatcta gtgcagatag atatcaaact
    28801 gctgaagaat tgatagaaga tatagagtat atagaaaaaa atattgattt agattttata
    28861 aaagaatatg atgattttgc aactaagaaa attgatgaaa aggaaattaa taaagttgta
    28921 aatccaatac ttgcaaaacc agcccctgaa aaagtggtta agcctgttga agtagctgat
    28981 ttggatgatg atgaagatta ctatgatgat ttttatgaag aagatgaaga agaggaagag
    29041 ataatgagag ctaaaaagaa tcagagaact aaaagtgctc caagtaagag aactaagaaa
    29101 aagaagaaaa aacaggaaag cccaaaatct agaagaagat taaaagtaat tgcaactgtt
    29161 ttgatattga tattgtgtgc tcaagtattc ttagcatata agtttttatt ttctggaggg
    29221 tttggcaata aatctttgac tgttcctaat cttgtaaata tgacattaga agaagctcaa
    29281 agtgctgttg aaaaagaagg gttataccta agtgtaaaaa gcgaagagta taatagtgaa
    29341 gttgatgaaa attgtataat atcacagaca cctgaaggtg gaagtacaaa tatcaaaaag
    29401 ggtgatacta taaatgttgt tgtaagtaaa ggttcaagtc aggcatcggt tccaaatgta
    29461 gtgggactta ctctaagtaa tgcaaaacaa cttattgaag aaaataactt aaaagtggga
    29521 actgttaagt atgaatatag ttcaatatat aaagaaggaa cagttttaaa tcagagtcca
    29581 ggagctggtt catcaagagt gcaagaaggt gacgagataa gtttatatgt aagtaaaggt
    29641 tcagaaaaat caaatacaca gactccaaca gtaccaaata aaacaccaac aacaccaaat
    29701 aatgatacac caacagaacc tggttcaaac tcaggaagta gtggaggaag ctcaggaggt
    29761 tcaaattcag gaaatagtgg agggaactca ggaaataatg gaaacaactc aggaggttca
    29821 aactcaggaa atagtggagg gaactcagga ggctcaaatt caggagacaa tggagggaac
    29881 tcaggaggct caaattcagg agacaatgga gggagctcag gcggttcaaa ctcaggagac
    29941 aatggagata gttcaggagg ctcaaactca ggagataatg gaggaacttc atcaggcact
    30001 ggtgcaaata ttggtaaaac agaataaata ttaataaaat aagagctgtc cttttataga
    30061 aaatattttc tttaaagggc agtttgtttt gtataaaata ttgaattggt tataatataa
    30121 ggagaaaagc atttatgaaa aagaaaacag ttttaattac aggaggagct agaggaattg
    30181 gcaaagctat gtctaaagct tttgcaaaag aaggttataa tgtattagta aattttaata
    30241 agtcagaaaa tgaagctaaa gagttgtata ctagattaaa tgaagaaaat ttttctataa
    30301 aactttttaa ggctgatgtt tcaaatagag aagatgtaga gaatatggta gattattgta
    30361 taaaagaatt tggaggattg gatgtacttg taaacaatgc tggtataagt caagacaagt
    30421 tgtttacaga tataactgat gtagactggg ataatatgat gaatattaat ttaaaaggaa
    30481 gtttttattg ttcacaagtt gctttaaaat acatgatatc agaaaaaaaa ggaaatataa
    30541 ttaatatatc ttcaatctgg ggtatatcag gtgcttcttg tgaagtgcat tattctataa
    30601 caaaagcagg tataatagga atgacaaaag cattagctaa agaagtagga ccatcaaata
    30661 ttagagtaaa tagcatagct ccaggtgtca ttaatactga tatgttatct ggatataatg
    30721 aggaagatat agatattctt gtggaagaaa ctcctctaat gaggctagga actccagaag
    30781 atatagcaaa ttgtgctatt ttcttggcat cagacaaatc aaattttata actggtcaag
    30841 taattagtcc aaacggagga tttgttattt aaaaaaaatg tggtattata taaaaatagg
    30901 aaagaataac acgatatact actcataaac agtatgtgtt tatataaatt ttataaaggg
    30961 aggcatttga tgctagaagg aaaaattata aaggggatta gtggatttta ttatgtagat
    31021 acgcataatg gtatttatga atgtaaggct agaggaatat ttagaaaaca taaaataaca
    31081 cctctggttg gtgatagagt caaaataagc attgttgatg aggatgaaaa aaaaggtatc
    31141 ttagaagaaa tagacagtag agatacagaa cttataagac ctcctatagc aaatgtagat
    31201 aaggcactaa tagtattcgc aataaaaaat cctaaaccaa acttatctct tttagataga
    31261 tttatagttt tggcagaaaa agaaaattta gaaactgtaa taatccttac aaaagcagat
    31321 ttagatgata atgatacact agaaactgtt aaaaaaatat atgaacttag tggatacaaa
    31381 gttattcctg taagcaatat tactaaatta aatatagaga aagtaaaaga agagttaaaa
    31441 gaaaatgtag tagtgtttgc aggaccatct ggagttggaa aatcaagttt actaaatgaa
    31501 atagatgaaa actttaaact tcaaacagga gtggtaagtg ataaaataaa aaggggaaaa
    31561 catactactc gtcatgctga acttttaaaa ttggaatttg gtggaatggt tgcagataca
    31621 ccaggcttta gttctcttgc acttgaagat atagaggaag ttgaacttaa agattatttt
    31681 atagaatttg ataaatttaa tgattgtaag tttggttcaa aatgtattca tgaaaatgaa
    31741 cctaattgtg ctataaaaga agctgttgca aatggagaaa tatctaaaga aagatatgag
    31801 agttatatac agctactaaa tgaaataaga caaaataata gtaggaggta ttagaaacat
    31861 gattaaatta gcaccatcaa tattatcagc agattttgca aaattattag aggatgtaag
    31921 aaaggtagag agtgcaggat gtgaatatct tcatatcgat gtaatggatg gacactttgt
    31981 accaaacatt acattaggac cacttgtagt caaaagtttg aagaaagaaa atataaatat
    32041 ggtatttgat gctcatctta tgatagaaaa tccagaccag tatattgaag agtttgtaaa
    32101 agcaggatgt gatataataa ctgttcatca agaggcttgt gttcatctac atagaactat
    32161 acaaaatata aaatcacatg gaataaaagc aggtgtagtg cttaatccag ctacaccaat
    32221 agatactatt aaacatgtac tacctgattt agatatggta ttattaatgt ctgttaatcc
    32281 tggatttgga ggacaatcat ttataccttg tgttttagat aagattaaag agttaaaagc
    32341 tattatagat agtcaaggat taaatattga tatagaagtt gatggtggta taagccctaa
    32401 aaatgtggat aaagttgtac aagcaggagc taatgtaata gtagcaggtt ctgcaatatt
    32461 tggaagtgat gacattcaag aaacagttaa tttatttaga aagaatgctt ctcttgaaga
    32521 attagtttaa atttaagaat gaaaatctgt attgttttaa atggtgaaat agaagattac
    32581 gaagttacaa gaggtattat aattaaagaa tgttatgact gcataatatg tgcagatgga
    32641 ggagcaaatc acacttataa aatggaaata atgccagatt atatattagg agacttagat
    32701 tcagtagaag aagaaaagat aaacttctat aaaaataaag gtgttaaatt tgaaaaattt
    32761 ccatctaaaa aagatgagac tgatacagag ctttgtcttt ttttagctaa gacacttaaa
    32821 gcaaatcata ttgatttttt tggtgcttta ggaggtagga ttgaccacac tcttgcaaat
    32881 ataaagctat tatattattt aaaagaagat ggtatatatt ctaggatact ttctgataaa
    32941 gaagagatgt atatagttga aaatgaagaa atttcactgt atggaaatcc aggagacact
    33001 atttctgtaa tagctataaa aggtgatgct aagggtgtaa cacttaccgg attagaatat
    33061 cctctcgata attattatat gagatactct gtacctattg gaatatcaaa tgttatgttg
    33121 agtaattctt gtaagattaa agtagagcaa ggatgtgtac ttgtagttag aaatttataa
    33181 aatttggttt tgacaattga ttttatattg tagagcagat acaatcaagt aaaatatatt
    33241 tatgattgta tctgcttttt agtatataat tataaataga taataaactt tgacataagg
    33301 gggatttttt gtggtagata gtattatttt tgatttagat ggaacgttgt gggattcaac
    33361 tgaagaagta tgcaaagttt ggcaggatgt tttaagtaaa cataaagaaa tagatttaag
    33421 tgtcacaaaa gatttattta gaagtcttat ggggctttct tttgaggaaa tagcaaatcg
    33481 tttatttcca aatttaagtg aagaagaaag aaataattta ttaaatgaat gttctttgaa
    33541 agaatgtgaa tatttatctg aaaatggagc taaattattt gatgatatag aaaatactct
    33601 taaattacta tctaaaaaat ataaattatt tatagtaagt aattgtcaag ctggatatat
    33661 agaatctttt ttaaaagcac ataaactaga acagtatttt gtagattttg aatgtccagg
    33721 taatactggt ttgcataaag gggaaaataa taaacttata attgaaagaa ataaattaaa
    33781 aaacccaatc tatattggag atactcaagg tgatgcaaat agtgctaagt ttgcaggtat
    33841 cccttttata tatgctaaat atggatttgg gaatgtagat gtatatgatt attttataga
    33901 ctcatttaaa gatttgttag aacatgatat attaaaatag gatgagttta aaaattatat
    33961 taaaataata aaaaagttat ggggggattt aaaaatggaa ttacaggata ctatttttaa
    34021 aagacaaagt gtaagaaagt ttaaaaatca agatgtgtca gatgaagata ttttaaaaat
    34081 gataaaagca gcaggtgcag ctccatcagg aaagaatatt caaaactggc attttgtcat
    34141 tataaaacgt cgtgacttaa tggaaaagat agcagatgtg ataactaaaa agcaacaaga
    34201 aatacttgta gaaatggaaa aagtatcagt agataaggct aatagattta gaaaatttgt
    34261 taaaaacttt acactatttt acttaaaagc tccagtttta gtattagttt ttacaaaggt
    34321 atataatcca tcaggatatt atgaattaga gcttatagat gcacctaagg aaactataga
    34381 taaattattc ataagaaatc caggtatgca gagtttaggt gctgcgattg aaaactttac
    34441 attatcagca attgaacttg ggtatggttc ttgttggttg acaagtcaaa actacgcagc
    34501 agatgaaata gaagctgttt tagaagcaga aactggattt gaaaaaggag agtatttttt
    34561 aggtgcaatg ttggctcttg gagtgccaga ggataatttg aagagcccat ctaaaaaacc
    34621 agtagaagaa atatgtacat ttataaaata aaagacaata atttttaaga ttcaaaatga
    34681 gttaaaaata aatagttaaa aataaaaagg taggttttat tgatattaag tttatgtttc
    34741 aaatcattga tttaattaat gcaataaaaa ctaccttttt tgtgcatatt aattttgaat
    34801 aactccaaat ctttagaaaa tctttagaaa agtatatgta atatcttaag tttttaactt
    34861 taatattaag tatataaaat gaaaaaacta aatttatact agagggaggt ctctaaggtg
    34921 tacattaaat aaaaataact attagaaaga tataaatata taaaaaaatg gaaaaacttc
    34981 tatcatattg tataatcata tatgtaaaga aaatttataa attaattggt ataaaggaga
    35041 ttaaaatgaa ttcatataat attttggtgg tagaagatga aaaggaaata gcagatgcta
    35101 tagagatata cctattaaat caaggatata atgtttttaa aggatacaat ggattagaag
    35161 gacttaaggt tatagaaaat caagaaatac atttagcaat aattgatata atgatgccta
    35221 aaatggatgg aataacactt acaatgaagc ttagagaaaa tcataatttc ccagtaataa
    35281 tgctatctgc aaaatcagaa gaagttgata aaataatggg gcttaatata ggggcagacg
    35341 attatgtaac aaaacctttt aagcctttag agctattggc tagagtaaac tcacaactta
    35401 gaagatacac taagtattta aatatggttg aaaataaaga gcaaaaagta gatgatgatg
    35461 atggcgtgtt tgcaataggt ggattagaat taaatgaaaa tacaaaagaa gttagtgttg
    35521 atgggaagca tataaaagca actcccatag aatttaaaat actaagctta cttatgagaa
    35581 atgcaggaag agttttttct gctgatgaaa tatatgaaag agtttggaat gataatgctg
    35641 taaatacaga tacagttatg gtacatgtta ggaatataag ggagaaaata gaagtagacc
    35701 caaaaaatcc taaatattta aaggtggtgt ggggtgttgg atacaaaatt gaaaaaattc
    35761 aaagataaat atatagttac tattatagtt tttatactta tgttatcagc atcattaggt
    35821 atgattagtc aatattctac tattcaagca ggggctaaag gtggagcaaa gaatccattt
    35881 gaacaggaaa gttttgtaga taatatgtat aaaggaagtt atgttttata tcataacatg
    35941 aaagaagaac aagaaggtaa gatgatacaa ccctcaaaac tttttataag taaagaaact
    36001 atgaactata taaaaaatgt aagtaaagaa aaagatactt atgatggctc agagacttat
    36061 tatacagatg atagtattaa tgcagatttt aatcaaaact ttgaaaattg ggagtctttt
    36121 attaaagaat caggaaaaaa tttaaaatat tatttagttg ataaagaaag taactttgaa
    36181 ttttttaacg ataataaaga attaggagca cttgatacaa caaagaatta tgcttcaaaa
    36241 gaagattctg atgaaaataa atcaaaaaat acagaaatga gtgatgagga aagacaaaag
    36301 cagattaaag atataaagga aaactataga ttctacattg taatgaattt tgataaagat
    36361 ggaaaagtaa atgttttgga ttcttatgga gtaaatcaaa aagttattag tcaaatgtta
    36421 ttgtctaaag caagagaaga tttaatgaat acaactttag gtggaaatcc aatttcatat
    36481 aagctatctc caataaaaaa cgtgacatta gtatatgcag tacctaaggt aataagtaaa
    36541 ggggatggtg gagagtatag ttatggaaat atttataata atgatagtat aagttcatat
    36601 ataaataatg tagaaaataa ttcttactat aagatttctg gaatgatttt aaaaattata
    36661 ttagctatag ttgtgattgt agctttagca ttcccatata gaaaatctaa agaattacta
    36721 ggatttgata cattatcaag aataccatta gagatattat ttattattct tgctatttta
    36781 caaggaattg tagatttata tcctactagt ataataagta atactttgag tggaaattat
    36841 gtagaatatc tgataaacaa tgacataagt gctaaaatgg ctagtatatt ggtaagttta
    36901 atgaatctaa cttattggtt tgtaatattc tcaataatat ttgtatttat aatactttta
    36961 aaacatattt taaatgttgg aataaaagag tattttataa agaatactgt cacaggaatg
    37021 ttttttgtat ggttgataaa atcaggaaaa gtagttatta atcaaattag aataacagat
    37081 ttaaaagaaa agcctaataa aactatagct ataattttgg gaataaactt attaattata
    37141 gttataatgt gtagtttttg gttctttgga ataatacttg cattgatata ttcagtagta
    37201 ttatttaaga tattgtcaga ttactctaaa aagacaatat atgaatataa tcaactttta
    37261 gatgttacaa agaaaatttc agatggaaac ttagaagtaa atatggaaag agatttagga
    37321 ttttttaatc ctataaaaga tgaattagga aatattcaag ctggatttaa aaaagctgtt
    37381 gatgaagagg ttaagagtca aaagatgaaa acggagctta tatcaaacgt atcacatgac
    37441 ctaaaaacac ctctgacatc tataatcact tatatagatt tattaaaaga tgaaagtata
    37501 acagatgaaa atcgtaagtt gtatattgat acattagata gaaagtcaca aagattgcaa
    37561 catctaatag aagacttatt cgaagtaagt aaggtaaata gtggagatgt tcatttgaac
    37621 ataatgaatg tggatattgt gtctctaatg aaacaaacac ttttagaatt agatgacaaa
    37681 cttgcagatt catctctaat agtaaagaat aacttttcta atgaaaaaat aatattacca
    37741 ttagatagtc agcgtacatt tagagtattt gaaaatctta taataaatat aagcaaatat
    37801 gcaatgccaa attcaagagt gtatattgat attttagaaa cagacaataa agtaagtatt
    37861 atgcttaaaa acatgtctgc aactgagatt gattttagtg tagatgatat aatggaaaga
    37921 tttgtaagag gagataagtc acgcaacaca gaaggttctg gtcttggttt agcaatagca
    37981 aaaagtttta tagaattaca gggtggtaag atgaatataa gtgtggatgg tgatttattt
    38041 aaagttacaa ttacttttaa taaaaattag aatagacttc tttaataatt ataaaatcca
    38101 taaaataata ttttataggt attgttttaa agtagttttt aaacattatt tcaaaacaac
    38161 ttgtaaatct tattttaaaa tagaatgttg atttatttaa aaaaggtgaa tcctaatata
    38221 taagattcac ctttttattt tataaaatgt tacttagtgt tatagatatt ttaaatagtg
    38281 taaatttgga tttaccatta acataaggtt agtaatttct tttgaaatct tgtataagct
    38341 attttatatt atttaattac tattgtttgt actttacaat gtgacaaaga atttacttct
    38401 acagttttag tatttacctt aagcttgtta gtattatcat agatttcgtc aagcattgca
    38461 ttataagcag cattgatatt tttattgatg ttaagacttc ctttagaatc ctcatttttc
    38521 ataccattga agattctaac tacaattccg tctccttttt cttctttctt tattgcactt
    38581 actgtgaaat ttgaattatt tacattcata aaactatatt cattttcata tatttgtttt
    38641 tcatcattaa atacaaatat aagtctacca tttaaaaaat cagcatattc atatatttgt
    38701 ataggtgtta agaatctctt agcagtatta gctatatttg atttatcaaa tttattgttg
    38761 tagatgtaaa gaccaaagtt aaagtttaac tctttgagta attgtgcatc tggtgttgct
    38821 attatttttt ctccagaagc tcttcctggt ctataaagta aattttctct tcccatatat
    38881 ccaaatgacc taaatagtgt taatgctatt gtatctaaat tagcaccaac tatttgatat
    38941 tctctcacac aaccagttat taatgctact cctttttgtc catcttctaa agtaacaaaa
    39001 ctttgcattg gttcaatagt tataggcttt tcttgccatg agtaattgtc tcttttccat
    39061 aatgcaaggt ctttttctaa tgctgttggt ctttgtatta ttccaaattg ttgatctgct
    39121 atagaaaact tagatgctat ttccgtatta aataaaactc ttactctatg agataatgct
    39181 tggtcatttt ttatattaat attaaactta attatttgct ctttaggttc taaggtgatt
    39241 ttcattgtta ctggcatttt cacagaaact ttacctatag tcctttcttc tagtgaagct
    39301 ggtatggtca atgaatattt aagtgtcatt tcttcttgaa catttgattt tagcacttct
    39361 actgaagata cagaatctaa agatgaaaca taaatatctt ttcttggagg cgaatagttg
    39421 tatgaatctc catcatctcc attatcttca attacagctt ggtttttata agtcttatta
    39481 gactctttat ctaatatttc tactgaacca tttttattgg ctgttatttt atagtatttg
    39541 ttttctattt ttttacaact acttgttttt atttcacatt tatttttagt atctaattca
    39601 acaattagct gagtatatcc catgggtggt atatttttta ctgaaagtgc aatttttgcc
    39661 ctatatacag tttttggtat atatattttt ttacttgggt ttaattttat tgtttgagtt
    39721 aatatataat ctgtaatatc ttctttttct tttattatat aattaagaat ttctccattt
    39781 ttgttcttta tcacaaaatc ttgacctgga atataagtat caaattctac aacttcattt
    39841 ctagcttctg gtaatccatt gaatactgtt aatgttattt cttcattatt atttttgatt
    39901 tgagtactta taagtctcat atgaaaatct aacaaattta tactcaaatc tctggcttgt
    39961 ttgtatcttg tgtatacatc ttcatttgtt gtgtcactat tacaagaacc tatgctgtca
    40021 tgagctgcat tttcgaacat aagtttccat atatctttta aaattaggtg agggtattca
    40081 tttccaagtg aataacttaa tgttaataat ggttcaagta catttgtaat ataattttct
    40141 aatttattat tcattatctt aaggtctgac cttgaggaga atattgattt gtgtattctc
    40201 atatgtttag catttacaaa ttcaccttta agctctgtaa attcatttct ttcatttctt
    40261 actgaatcta catagttttc tatatcactt atttcgtatt cattttcagt atctatttta
    40321 ttagcttttt ttaatatgtc aggaaggttt tttcttattg gtgcttggtc aaatccattt
    40381 gggaaatata cgttattagt agaggattta accttaagtt ttccaattgt atcttttaaa
    40441 tattctttta aatctgaatc atcttctggt atattacctc catagtaata accaaatggt
    40501 atttgaactg ctaatacctt tgagccatca gaacctttcc atataaattc tgttgtatct
    40561 accatatcat cagaaactcc acgccaaaat aatgaactat ctattccaaa acctctatat
    40621 atttgtggca tttgagctga ttgtccaaaa gaatctggta catatccaac cctcataggt
    40681 tcgccaaatt cattgcatct atctattcca tagtaaaggt ttctaactat agattctcct
    40741 gatataacca attggtctgt ttgagtatac caaggtccta tagctaactt ttttctttga
    40801 actaaatctc ttattctata ttcatcctga ggtctccatt ttaaataatc atctaagaga
    40861 gaagcttgtg catccatagt aaagtattta aagtcttctt tttcttctaa tatgtctaat
    40921 atatcttgaa aatctttcat tagatatatt tttgaccttg atgttgtaaa ataccattct
    40981 ctatcccaat gactatgtgg aactacatgt acttttgtct tcttcataaa atcctcccta
    41041 aatttaattg agaattgaga gtacgctcaa ttctcaacta gctaaaatta aatctttaat
    41101 ttacattata tctaactcta tttcatcaaa ttctgtattt tccgcagttt catcttcatt
    41161 aaagtctact aaaattgttg ataatattgc tattactaaa gctccaaata tcgcacctac
    41221 taagtaagcc catccagaac ctactgatat aaatccatat aatccaccaa ctggaggcat
    41281 tatagcatgt acacctaata aagctgataa tcctacaccc aaagcacatc ctatcatatt
    41341 gacaggaact aattttaatg gattttttaa agtgaaagga attgcacctt ctgttattcc
    41401 aattataccc ataactatgt tgccttttcc tgtttcagat aatgtcttag agaatcttga
    41461 ttttctaatg aatgtagcta aaccatatcc tagtggaggg ataactattg cgcagtttac
    41521 caatattgct ggtagataga tgccctctaa caataatgca tttcctgcca tccaagctgc
    41581 tttatttacc ggtcctccta aatcaaatcc tatcattgaa cctaaaatta aagccaatac
    41641 caccgaattt gttccatttt gacacatttc agctacccaa gcatttaatg aagtatttat
    41701 gtttcctaaa ggccctgcta atacaacact cattaaaaac cccgttaatc caactgttat
    41761 aagtggcatt attataagtg gcatcattcc tgctgccgac ccagatattt taattttttt
    41821 ctttaaaaat ttgcaaatat atccagcaaa aaaacctgct gttactgctc ctaagaatcc
    41881 tgcattagta ttacttgcta tgagtccacc aataaaacct gcacccatag atggtttttc
    41941 acctattgaa aatgctataa atcctgctaa tacagtattt aatagaccta tgccagtcca
    42001 accaacttgt tccattaagt aaagaatatg ataaaaaccg gatacatttt tgtaagcatc
    42061 taaacttgtt atacccattg ctaaagctgt aagttttggt atagctacaa ctagagatga
    42121 gcctattaca agtggcaaca tatatgaaat acctgtcatt aagtgtcctt taagttcact
    42181 taaaagagag ttattttttt tactcatttt taatcctcct atataagttt gttatatttt
    42241 ttgataatat gttataatta cattagataa ttttttaatt tttgattttt ctcattctag
    42301 attagagtga gattcttttt attaagaaat agtttctata cactttgtta agacagcttc
    42361 tggttttttt aatgctacac ctattttaac ttttattact tttttaccat caaatctttc
    42421 cattccagat atagtttggt cagatgctat aagtataaag tctgcatctt gtgcttcttc
    42481 ttttgttata gtatttactc gtcccatagc accttgttgt tctactttga ttttatgccc
    42541 catttttgat gcagcttgtt ccaaagcttt tgctgccata ggtgtgtgtg ccaatcctgc
    42601 tatacatgat gttattgcta ctattttcat aattattcct ccttcatttt attagttata
    42661 tattttacta aatgacttgc atcactagca tttttaactt cacttataaa atcatcttcc
    42721 attaagcatg tggctaattt agatagagtt ttcaaatgta tatttccttc attttcatgt
    42781 ggagctaaca aactaaatac atatctaacc ttactatcat ctaaagtttt ccactctaac
    42841 tcgttagttg ttttaatata gagtatagaa gcttctttta catttgcact ttttgtatga
    42901 ggtatcgcaa atccatctct tattcctgtt ggaaattcgc tttctctttt tagaaggtct
    42961 tttaaaagag catctttatt agttgtaata cctagtatat aagcactgtc tgcaataaaa
    43021 tttaatactt cctctttgct ttttaagtct ttatctataa atatattctt ttcttgtagt
    43081 accatatatt ttttccactc cattcgtaat gtcttaactt atatttatat tgtaatcgtt
    43141 atcctaatta aattaaatat aactaatttc cacttcgaca tggaaattta tattatgata
    43201 ataactaatt tccatgtcga agtggaaata aattatgata atacaatttt attagagtaa
    43261 ttgtattata tgagtgtaaa tagtataatt tagaagaaat tctataaggg gggatattta
    43321 tgcacaagag attgctcacg ttatttaaac tattaaatga aagtgatgat aaaattactt
    43381 gtaaaacttt aagtaatcat ttaaaagtga gtgagagaac tataagaaat gatattactt
    43441 ctataaatga aactttagag aaaaatggtg ctattattaa aataaaaaaa ggagaaggat
    43501 attatataga tattcttaat ttagcattat accaacatta tctagcatta atatctgatg
    43561 atattatgga ttcaagtgaa ataccagatt ctcctataga aagaaatcaa tatattttaa
    43621 aatatattct ttataacaat acatatataa aactagaaga tttagctaat agcttgtatg
    43681 tgagtaaatt tacaatacta aatgatataa aaagaataaa gcctattttg tcaaagtata
    43741 atttaatatt agtttctaag ccatattatg gagttaaggt tgaagggaag gaaatagata
    43801 ttcgaagatg tatttctaat aatatgataa ataggaattt tgaaaattat ataattggaa
    43861 ttacagatag agaaatagaa ttatttaata atgtagattt aatagagctt cagaagatag
    43921 tgctaagtga aattaataaa tttaatatca atttcttaga ttttaatcta aaaaatttta
    43981 ttattcattt atctattact ataagcagaa tactaggtgg ttactgctta gataatgttt
    44041 tagatgtggt tttaacagat tttcaatcga atacggctgt tgaaaatata tttaattata
    44101 ttgagagtaa atatactata attatttcaa aggcagacag agtttattta tataatcatt
    44161 ttataactaa aagttctctt ttggataacg tttccaatag ggcagatacc aaaattatag
    44221 agtatgttga ggaaatttta gaagtaatca acaatcaata tacttttgac cttagaaatg
    44281 atagtgtatt atttgatgat ttagtactgc actttaaatc aattcttaat tctaaatctt
    44341 ataatttaaa taaggtgaat ccccttataa atacaataaa aagtaattat cctttagcat
    44401 ttgaaataag tttaaatgct atagaaaaag tttttaaaaa tagtatttac tctttaacag
    44461 aagatgaaat tggatatgta tccctacata taggtgctgg aatagagaga ttttttcaaa
    44521 acaatattaa gtgtaaaaac gtagtattag tatgtggttc agggtatggt tcaagtaggt
    44581 tattagaggt tcaattaaac aaagtttttc atgataaaat aaatatactt caatgtctat
    44641 catttaatca atttttagct agtgaattgt cagatgtaga tataataata tcgacaattc
    44701 ctttaaatca tgatagtatt cctattgtat tagtagattt aaaactatta aaaaaagata
    44761 tagagaatat atctaagtca atcactaata attctcgtat ttatagtaat cttttggaca
    44821 atttctttga taaaaattta tttattgtta atcctaaaat caaagagaag gatgagctta
    44881 taaagttgat gtgcaacaaa ttaactcaaa gtgaaattgt aattccatca tttactgaat
    44941 ctgtattcta cagagaaagt ttatcttcta ccaatataga tgatttttta gctatacctc
    45001 atcctatgga attaagctct ataaaaacta agatttgtat ttccatattg aatgaaccaa
    45061 tatattggag tgaagattct actgttaaat taatcatgat gttggctata aataaagatg
    45121 attatataaa aataaactcc atttatgata tccttttaaa gataattcat gacaatgata
    45181 ttagagatag tatatctaat tgtaatgatt ttgatagttt tctttccata atcaagtcta
    45241 taatataaaa ttttatatta cataagtttt ataaaaaata aatagaacaa ttttttgttg
    45301 ataatataaa tagtaatgag taatttttat attattttct attactttat actgattgta
    45361 attagataca atagagggtc tgtctcaaaa tagagataat ccttttttta ttgttgaaat
    45421 gataaaaaca tatttgattt catataaaaa agagtgtctc atgaactaaa aagttcattt
    45481 tgagacatcc tctttattat tttatattaa ttatctcttg tatatactac tatagcatcc
    45541 ctcagaaact tagttagtcc aggctgttct ttatcataat aagatgtaaa gcgttcgtca
    45601 catacataca tctgtgctaa agaggcatga gcttccttag aatatgtgct ccaagtgtag
    45661 ctcaaccatt tatgatgtaa tcttgcaact tcttgagcaa gttcactgga ggcatcacca
    45721 gttttaaaag cttttttaag cttactaatt atttcaatgc ttagattttg ccaatcttca
    45781 taatcttgtt tagacatatt tttaaatttt ttatttgagg caactataat atctttacca
    45841 taattctctc taatttcagt tccataattt ttttcatttt catcaatcat cttttcttta
    45901 aaaccttcaa atttttctat atctgtcata gtgtattttc cctccttcag agctatagtt
    45961 ttagttacat tttctattag taaatcaatt tgctttcttt tgactagtaa tttattatgg
    46021 tgttttttta acgcacttaa actatcgaag tttggtgaat ttataatgtt ttttatattt
    46081 tctaagttaa ttcctaattc tctataaaaa agtatttgtt gaagtttatt aacttcattt
    46141 tgaccatata tacgataacc tgaagaattt attttaagtg gcttaagaag acctatttca
    46201 tcataatatc taagtgtcct agtacttata ccagctagtt tacttaattt ttgaactgta
    46261 tattccataa ttagtacctc ctataaacta aatatacact tttacgcaac gtaaatgtca
    46321 atatattaaa atataaaaat ttatatcttt taataaaaat ataaaaaaat atctttactg
    46381 gatattttac acacaagtgt caatactcac tagtgaaaat taaaaaataa aatttataga
    46441 ctatttttat taaaatatag aaggtctata gtttaggagg aactgtatga atttaaaaag
    46501 aagcaatgaa aaacgagaag agtatagaag aatgtattca gataaagaaa gttttttaag
    46561 tttgattcaa aattttacaa gtgtctcaat cgcaaaggaa ttaactctta aaaatataga
    46621 attagaaaca tcttttatat gtgaatataa aggaaaagaa gttgatgtaa tttataaagt
    46681 gttttctaaa aatggtaaag tatcacatta tatagtatta gagtttcaaa cagaaatgga
    46741 tactgaaatt gtaccaagat taaaatcgta tagagaacag atttggaaga gttttattat
    46801 gaaaaaaagt cttgaagaaa tagaagataa aaattttaag cttcctaaag ttataccagt
    46861 cgttttatat agtggacctg aaaggttaag cagaaaaaaa ggaattttgg atattgtaga
    46921 atctatatcg gagttcagta ataattctag tatgaaaaat taaaactaca taatatgttt
    46981 attggtctaa aatggaaaac tgtcgcataa acttgaatat gaaaatattt atagatacag
    47041 gttctatgtg gaggtgttcc atgagaaata acaagtctaa ggtattgcta ggaatacttt
    47101 gtctggcaac aggaatggct gtaattcttt caatgttgct tcctggctgg atttggtcag
    47161 cacttaccgc attaatactt attggatgtg gagcattatt atttttttgt taaaatagtt
    47221 ttaactataa agtgtggggt gagtattgat gaaagtagta acaataaaat taccaaaatg
    47281 gatttcaagt ataatcctaa aatttatgag aaagagtaaa aatgattaaa ttaaaaagcc
    47341 tacttacgga agtaggcttt taaacgtggt tactaagctc tttcaatttt accagaacgt
    47401 aaacatctag tacaaacttt tactctctta ggagctccat ctataatcgc tcttacgctt
    47461 cttaagttag ctgaccatgt tcttttatta tgtttatttg agtgtgatac ttggtttcca
    47521 gaaaccttac ctttaccaca tacgctacat acttttgcca tctacgcaca cctccttaaa
    47581 atgataacta tttaaagact aaaaacatat ttatattatc ataaataaca aaaatttgca
    47641 atagaaatat atatttgcct tacacatatt gaagaatttc ttattatcat ataaaattat
    47701 atatataatt ttatataaag taaatatatt tggaaaataa ttattatttt tctttgaata
    47761 tatatactat agaagaaatt ttatccaaaa acttttctag gtttaaatta taccatattt
    47821 atagtatgat atgattataa ttttatataa taaataagta agaatagtaa aaaataaatt
    47881 aagaaatgtt tttaataaaa ataagcttaa gggggtcaac catgagtgca aaggtaacga
    47941 atcaatatgg aagtatagaa atagataatc aagtaatagc tcaagtcgta tatagagctg
    48001 caatggaaag ctatggctta gtaggtttag catataagtc taaaggaata gtagagctat
    48061 taaaaggtga gaacgcaact aaaggtgtaa gagttgagga agtagaagaa gatgccatag
    48121 caatagaact ttatgttata atacaatatg gtacaaatat atctactgtt gccaataata
    48181 taatagatag agtaaaatat gtagttgaaa aaatgactgg cgtaagagtt actagaattg
    48241 atattaatgt acaaggaata agagttaagt aatttcatag gaggaaacaa atgattcagt
    48301 atatagatgg taaaaggtta agggagatgt ttatttcagg tgcaaacaat ctccaaaaca
    48361 ataaagattt agttgacaag ttaaatgtat tccctgtacc agatggagat acaggaacta
    48421 atatgtcatt aacaatatct tatgccttaa aagaattagc aaaagttgaa actgataata
    48481 tatcagacat cggaaaagca ttatctaaag gctctttaat gggagctaga ggaaactcag
    48541 gagttatact ttcacaaata atcagaggta tagctaaatc tatagaagga aaaagtaaat
    48601 tatcaacaga agatttagca aaagctttta aaaatggttc agacacagca tataaagctg
    48661 tgataaaacc aattgaagga actatactta ctgtggttag agaaagtgga gattttgcaa
    48721 taaaaactgc aaaaaaagaa aaagatgtag taaagttttt aagtatgctt gtgaaggagt
    48781 ccaattcttc attagagaga actccagacc ttctaaagaa tctaaaagag gctggtgtag
    48841 ttgactctgg tggaaagggt cttgtactta tatatgaagg aatgttagct tctataaaag
    48901 gcaataatat agaaataaaa aacgctgacc tagatactaa tatttcaaca agtatggatt
    48961 ttgcaaagag tactattagt acagatgata taaaatattg ttattgtaca gaatttattc
    49021 tagaaagttc taaggtagaa gatactaaaa taagagacat aatgatggct tatggtgata
    49081 gcctagcagt agttggagat gatggagtca taaaggtaca tgtacacact aatgacccag
    49141 gaaatgtact tcaagaagct ctaaagtatg gtcaattatt aactataaaa atagaaaata
    49201 tgaagttaca acatgaaaat acattactag atgtagaaga aaagaaagaa aatgatagtg
    49261 aacctttaga agaagaaaaa gagtttggat ttatagctac ttctatgggt gaaggtttgg
    49321 caaatatatt taaagatttt ggagttgacc atataataga aggtggtcaa actatgaatc
    49381 caagtactga agattttatg aatgctataa aggatataaa tgctaaaaat atatttattt
    49441 tcccaaataa cagtaatata ataatggctg ctaatcaagc aaaagaattg agtgataaaa
    49501 atataatagt tatacctacg aaaaacacac ctcaagggtt tgctgcacta gtaacattta
    49561 atggagaatt aagtgaagat gaaaataaag aagctatgat gaatgcctta agctcagtta
    49621 aatcaggtca agtaactttt gctgttaggg atacagtgat gaacgaaatt gatgttaaag
    49681 aaggtaatat aattggaatt gcagaaggaa atttattatc agcaggagat tatgtggatg
    49741 aagtaacatc aaaccttatt gaaaagttgg ttgatgaaga tactgctata ataacattat
    49801 tctttggtga agatgttaca gaatctcaag caaatgaact acgtacttct ttagaagaaa
    49861 aatttgaaga tgtagatgta gagttatatt atggaggaca acctctttat tattacttaa
    49921 tttcagttga ataatgatta taagaacctg tatgaccaag tagcttttat aaaattggtt
    49981 gtacaggatt tttgtgtagt aggtgatata tttgttggat ttatataaag atgttcaata
    50041 tgttaaggga ataggaccta aaaaagcaga taagttaaat aagctgggta tatttacact
    50101 aaaagaccta ttgtattatt ttccaagaca atttgaagat agaaataatc taaagaaaat
    50161 agcacaatta gaagatagtg agaaagttac aataaaagca gtaatatcaa gtataaatac
    50221 atttagccca aaagaaggga tgactttaac aaaaattgat gtaaaagatg agacaggttc
    50281 ggctaaatta gtatttttta ataagagtta tataaaaaat acttttcgtc caggagattc
    50341 aatattagtt tttgggaagg ttaagaaaaa gtttaataac ttagaactta catcatgtga
    50401 attagaatat cttactaatt cacctaagaa tacatgtaga tttatgcctg tgtaccagct
    50461 tacatatggt gttacaaata aagaaattat gagtataatt agaacagtac ttgaagataa
    50521 agacttaatt atacaagaat atatgccaca gagaattata gataaatata gattatgtag
    50581 tatagatttt gcagttagaa acatacattc accaaatagt aaggaatcat taaaaatagc
    50641 tttatataga attgtatttg aagaattact tatactacaa ctagggttgt tcgtatttaa
    50701 aagtggaaga aacaaagaag atggaataaa atttgaaaca agtaaagatt taaaaaaaat
    50761 aataaatgct ttaccattta aactgactaa agctcaaaac agagcattag gtgaaattat
    50821 acaagatatg gactcagaga aaataatgaa tagattggtt caaggtgatg taggaagtgg
    50881 taagacagta gtagctctct tagcacttgc aaattgcgtt ttaaatggtt accaaggtgc
    50941 tttgatggct cctacagaga tattagcagg gcaacattat atttcactta ctgagtctct
    51001 aaaagatttt ggaataaatg taggtctatt aataggtagt cttacaaaaa aacaaaagga
    51061 tacagtattg gaacaagtaa agaataatga gattgatata ttaataggta cacatgcact
    51121 aattgaagac aaggttgaat ttaataatat tggtttagtt ataacagatg aacagcatag
    51181 atttggtgtt atgcaaagga gcaaactttc attgaaaggt gtaaatcctg atatactagt
    51241 aatgacagca acaccaatac caagaacttt agcacttata ctttatggag acttagatat
    51301 ttctattata gatgaacttc ctccaggaag acagccaata gaaacacttg ctattgaaaa
    51361 aagtaagaga gatagagcat ataacaacct tgtaagaaga gaggttgaat cagggagaca
    51421 ggtgtatatt gtatgtcctc tggtagaaga aagtgaagcc atagaagcca aatcagcagt
    51481 tgaacttgtt gaggagttaa gagcggaata ttttcacgac ttaaggcttg ggttgcttca
    51541 tggcaaaatg aagtcaagtg aaaaagatga agtaatggga ctttttaaaa ataaagaaat
    51601 agatatttta gtttcaacaa cagtaataga agttggtgtc aatgtgccaa atgcaacatt
    51661 aatgataata gaaaatgcag aaagatttgg acttgcacaa ttacaccagc ttagagggag
    51721 agttggaaga ggaagtcata aatcgtactg tgtactaatt tatgattcta aaacagatgt
    51781 atgtagacaa agaatggcta taatggaaga gaccaatgat ggttttaaga tttcagagaa
    51841 ggatttagaa ataagagggc ctggggaatt ttttgggaca aggcaacatg gtcttccaga
    51901 acttaaggta gcaaacttat ttaaacatat aaaaatactg aagttagcac agcaagaagc
    51961 tcgatatata ttgggtgaag ataataatct acaattgaaa gaaaacatgg cactcaaaaa
    52021 agaaattata gataaattta aagatacact gaaagaaatt tcattaaatt aattttaaat
    52081 tatgttaaaa tattactaat gtaataatgt gctgaaggga gattgtcata ttgagagtaa
    52141 tttcaggaaa agcgagagga ttaaaactaa atactccaaa aaatgaagat gtaaggccaa
    52201 ctacagatag agtaaaagag tctctattta atatgataaa ttcatatata atggaaagtg
    52261 aagttctaga tttatttgct gggactggct ctttaggaat agagtgctta tctagaggtg
    52321 ccaaggcatg tacttttgtg gatatcagta aggaaagcat agatattgtt aagtccaata
    52381 taaaaaaggc aagagttgaa agcgaaagta ttattttaaa ccttgatttt aaaactgcaa
    52441 tagataaact taaattacaa aatagtaaat ttgacataat ttttatggac cctccgtatt
    52501 ataaaaatat gtttatagaa gctattgaaa aaattgataa ttccaaccta ttgaacgaag
    52561 atggaataat agttgtagaa catgatacga atgatttatt tccagataag atatgtaaat
    52621 tagagaaaac tagagataag aaatatggaa atactacatt aactttttat aagatggagg
    52681 cataatatgg aaaataaacc tagaaaagct atatttgcag gaagttttga cccaattact
    52741 aatggacatt tagatattat ttgcagggct tcaaagttat ttgacgaatt acaaatagga
    52801 gtattaaata atcctaataa aaagggtcta tttagctttg atgaaagagt aaaacttata
    52861 gaaaaaagta caagccattt aaataatata aaagttgtga cttttgatgg tttattaata
    52921 aattactgtc aagaaaatgg aattggagca ctagttagag gcgtgagaag tggtgctgat
    52981 gttgattatg aacttcagat ggcgcatatg aatagagagc ttaatccaga tatagagact
    53041 ataattttac caagttgtac aaaatattca tttataagtt catctttaat aaaagaggtt
    53101 ttgctctttg atgctgatat aaaaaatttg gttccaaaga ttgttttgga agagttaaag
    53161 aaaaaaacta gtgggggtaa ttgatatatg aagatagatt tagaaatgat tgaactattt
    53221 gagcagttag aggagatatt tagaagtgct tctacaattc ctttctcaca taaatgcaca
    53281 gtggataaag acgaagtttt agcaataatt aatgatataa gaactttaat accagaagaa
    53341 gtaacacagg cagtatggat taataaagaa agaaataaaa taataagtca agctaagcaa
    53401 gatgctacaa atatagttga acaagctaaa aaagaagctg agagaataca acaagaatat
    53461 caagacaaca tagaggaatt aaagaaaaat tctgaagatg tagtaaaggc atatgtagaa
    53521 tccagtgaac ctgttgttca agcagaccaa agagctaaag atatagttga tagagctgag
    53581 agaatagcca atgaaataag aattgggtca attgaatatg cagaagatgt gctttctagt
    53641 gttgagtata atttaaaaga aatattagaa gaagtaaaaa gagataaagc tgaacttaga
    53701 cctaaaaaat aaattttaaa taaataaaaa tggagctatc acacaaaaaa ttctaattga
    53761 tgtgtgatag ctctctttta atacaacaat tttttgttat ctaattgtac ttttcatatc
    53821 acttatattt cattttgata ttataatgca atttaatctt ttatttgttt aaatcagatg
    53881 ctgtattaat aggattctta attgctatgt taacatctac agctttttat tattgtatat
    53941 taaaaagatg agtaattagt ttttaaatgg gtgaaaatag attggcaaat atcaattgta
    54001 aatattagaa acgttgtcat agaaaaaaac tatattaaaa aaaagtacat agaaaaaact
    54061 gattagacaa taaatacatg ctttgataat attttaaatg gaataaaaat gtgtagaatt
    54121 ataatgaaaa agaaaataaa atggagggag taaaagtggg tatgttaaaa aagttatgtt
    54181 cactagctat ggtggcaatt atgactacaa cacttataac agggtgtaca agtggaaatg
    54241 gaaaagattc aaaaaaggat ggcgaaaaag aaaaactagt tctttggatg ccaccagtag
    54301 aaaataatat gaaggaagtt tgggacccta ttttagataa atttgaggaa aaaaataact
    54361 gtgaagtaga tttacagata attccttggg ataattattc tgaaaaattt gcaacagcta
    54421 taagtgctgg cgaaggtcca gatgtagggt atatgtatgc agaaatgtat ccacagttta
    54481 tagaaagtgg agcagtagaa gatttgacta attatgcaac taaagaagat aaagagcaat
    54541 ctatttatat aaaaacatct gaaatgatgg gtggaatgta tggtatgcca ttccaagcag
    54601 caaatccagg ggtactatac tataacaagg atattttaga gaaattagga gaaaaacctc
    54661 ctaaaacatg ggaagatttt aaaagaattt gtaaaaaagc aacacaagat actgatggtg
    54721 atggaaagat agaccaatgg ggattagctc agggatgggg agctaaaact tttggtaact
    54781 taaattggaa ctggtatcct tatttatggc aagctggtgg agatatattt aataatgatt
    54841 taaaatcagt taaatttaat gataagagtg gtttagaagc agctaatttc ttaaaagaat
    54901 tacaagcata tgtgcctgaa gattctttat ctaaagatag taatgaaatg atagaaagtg
    54961 tatttggccc aggaaaagca gcatttacaa taatgttatc ttctgctgca acaagtgtat
    55021 ttgatgaatc attcccagac ttaaattggg gatttgtaac tggactagaa gataagaaag
    55081 cagcaacttt tggagcagta gaccatttat ctttgatgtc atctgcgaaa aataaagaac
    55141 ttgcgtacaa gttaatacaa catatgttaa gtgttgaatc aatgacagaa tttcataaag
    55201 caataccaag agcaccaata acaaaaggtg aaccatatca aggtgatgaa agattcaaag
    55261 aaatggtgga aaatgacaag gatgtataca gaccattagt agtaggacct catggagttg
    55321 aaatatatga atatttatgg aaagaacttc aaactatgat ttcaggagat aaaactccaa
    55381 aacaagcatt agatgatgct gcaaaatatt caaatgattt attagcacaa taaaagttta
    55441 aagctgtaat atgttgtaaa gtactttaca gattaaaatt agcattgtat ttataaatac
    55501 aatgctaata tttatattgg agaggataaa atggaaaact tagttagaga gtttgaagaa
    55561 aattcaaaaa gaaaaaaaac aaaattaaat attaaaccat atatgtatat attgccactg
    55621 ggaataattt tagtgacgtt ttatgtgata ccaataataa tgtcaatata ctttagtttt
    55681 acaaagtata atattattag tccagctact tttataggtt tagaaaatta taaaaaatta
    55741 tttacagatg aaacattaaa agtatctatt ataaatacta ttaaatttac tattgttgta
    55801 gtaccttgcc aaactatatt atcattgatt ttggcagttt ggattacagg aaagggaaat
    55861 agtaaaatag cttcatttgc taaaggtgct atatttatac cagtattatc atctatggtt
    55921 ttgataggta tggtatggag agctttattg aatggagaag gttctattat atatcaggta
    55981 ttaggtgctt ttggaataga gtcatctaaa cttttaggag atagtaagac agcattacct
    56041 acacttatgt ttatatctat gtggaaaaat atagggtatt tcatggtgat ttatatttca
    56101 gctataatga atttaccaaa acactgctat gaagtagcta aggttgatgg ggctacaaaa
    56161 cttcaagaat ttataaaaat aactgtacct ttattgaaac caactacaat aatggttgta
    56221 tttttagggg cgatatggtc actacaagta tttgatttag tttatactgt gacaggtgga
    56281 ggcccaggta tatctactat gagtatagtt atgcatgcat ttaacttaaa ctttaaaaac
    56341 tttaattctg gatatgcaat gactgtagca aacgtattat ttttattaat agcagtagtt
    56401 tctattttac aaaataaact tgtaaaacga gacaattcag atttttagaa aggtaggtat
    56461 aatatgaaaa caacaagaag aatattgagt gatggtttac ttttatttat agcgtgtgca
    56521 agtttggtac cttttatata catgttgata atatcattga agataacata taactcatat
    56581 agtttggata tatctttctc aacagtaacc cttcaaaact atatagatat ctttactaaa
    56641 aaagggtttg cacaatattt tttaaataca gcaatagtat ctttttcagg tgtattatta
    56701 aatttagtat ttagtacatt agcaggatat tcttttgcga agatggattt taaaggcagt
    56761 gataagttat ttttatttat gataatgact ttaattatac cttctcaagt tacaatgata
    56821 ccactatata taataatgaa acatttagga tggataaata gttatcttgc acttattatg
    56881 ccaataccaa ctgcatttgg tgtatttata atgagacaag ctattttagg agtgccaaaa
    56941 gagttattag aatcagcaaa gatagatggt tgctcggact ttagaatttt aatacagata
    57001 gttttaccac taatcaaacc agcattaatt acactagcaa tatttacttt tatgggagcg
    57061 tggaatgagt ttatgtggcc tcttatagcg acaactaagg atgcaatgag aacattaaca
    57121 gttggattat ctactcttaa gacattccag ataactaatt atggacagat gatggcaggt
    57181 gctacaataa catttttacc tccatttatt ttctatttga ttttgcagag taaatttgtt
    57241 gaaggtgtgt ctttatctgg cataaaaggt taaatagtat aatttaataa tataaaataa
    57301 acttatataa atatggagga atttaaacta tggaaatttc atatgtactg aaagattgca
    57361 catttaaaca taataaatac tcagttatag aaactgaaac ttgggaagat aaggatttgg
    57421 atattgtagt agctaaaggt gaaaaatttg catttcaaat tatgctaaaa gcaacagaag
    57481 aatttaattg tacaattgat taaaaaatag ctacgcacac tcgtgacttt agtcatgagt
    57541 tagtagctaa attagtcagc atatagggaa acctatatgt agagatagga tagaacctat
    57601 ccaatactac ttgaattgct ggaaacccct aaagctaacc aaactaaaac ataaggatga
    57661 aataaaccta agtgtgaaag ttgcgaaagt agaaaaaatt ggttagatgg tataaggtta
    57721 aaccctaagt actttaaaat gggcaatcag caggtaa
//
LOCUS       DAMKOJ010000016        54557 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000016 DAMKOJ010000000
VERSION     DAMKOJ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54557
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.017"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            3..79
                     /locus_tag="PC592_001078"
     tRNA            3..79
                     /locus_tag="PC592_001078"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Asp,seq:gtc)
     gene            90..164
                     /locus_tag="PC592_001079"
     tRNA            90..164
                     /locus_tag="PC592_001079"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:122..124,aa:Gly,seq:gcc)
     gene            174..247
                     /locus_tag="PC592_001080"
     tRNA            174..247
                     /locus_tag="PC592_001080"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:208..210,aa:Arg,seq:tct)
     gene            1158..1997
                     /locus_tag="PC592_001081"
     CDS             1158..1997
                     /locus_tag="PC592_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDF4055084.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            1994..3175
                     /locus_tag="PC592_001082"
     CDS             1994..3175
                     /locus_tag="PC592_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055085.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMNDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVHGTIEDPIQGQKEVY
                     LKANIPQGVTIEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKKNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVNLNDNKDNDALKNYKLSKEQVTIKGKKEDIDKINYIKTKPIDLADLANGE
                     EKEVSLEVPEGITLEGASITIKLNDTKQLSAEFLYSAGDIELRNIPTNMDNPSVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            3479..4381
                     /gene="ptb"
                     /locus_tag="PC592_001083"
     CDS             3479..4381
                     /gene="ptb"
                     /locus_tag="PC592_001083"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HDF4055086.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            4403..5482
                     /gene="buk"
                     /locus_tag="PC592_001084"
     CDS             4403..5482
                     /gene="buk"
                     /locus_tag="PC592_001084"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF4055087.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            5472..6149
                     /locus_tag="PC592_001085"
     CDS             5472..6149
                     /locus_tag="PC592_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4055088.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6192..6407
                     /locus_tag="PC592_001086"
     CDS             6192..6407
                     /locus_tag="PC592_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4055089.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            6436..7515
                     /locus_tag="PC592_001087"
     CDS             6436..7515
                     /locus_tag="PC592_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF4055090.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGRLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            7515..8267
                     /locus_tag="PC592_001088"
     CDS             7515..8267
                     /locus_tag="PC592_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF4055091.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8268..8825
                     /locus_tag="PC592_001089"
     CDS             8268..8825
                     /locus_tag="PC592_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF4055092.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            8997..10343
                     /locus_tag="PC592_001090"
     CDS             8997..10343
                     /locus_tag="PC592_001090"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDF4055093.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCMPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQSAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSELASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            10610..12442
                     /gene="glmS"
                     /locus_tag="PC592_001091"
     CDS             10610..12442
                     /gene="glmS"
                     /locus_tag="PC592_001091"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDF4055094.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEEEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELVSEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIVLDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKDIPSKIQEIL
                     DNEEYIKEVAKTVVNSDHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            12934..14229
                     /locus_tag="PC592_001092"
     CDS             12934..14229
                     /locus_tag="PC592_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HDF4055095.1"
                     /translation="MANDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDKKDEVLEQALKTKRIDIDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADNENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFENSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGFTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFTSNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFVLVDNRTWDEYIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            14700..15437
                     /locus_tag="PC592_001093"
     CDS             14700..15437
                     /locus_tag="PC592_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HDF4055096.1"
                     /translation="MKRVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNIKINSVINHNLSNKEFYNIFIEIINNLKLDKKGINWNRKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGRTLIYIATPIIKLDY"
     gene            15458..16711
                     /gene="murA"
                     /locus_tag="PC592_001094"
     CDS             15458..16711
                     /gene="murA"
                     /locus_tag="PC592_001094"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDF4055097.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            16798..17862
                     /gene="spoIID"
                     /locus_tag="PC592_001095"
     CDS             16798..17862
                     /gene="spoIID"
                     /locus_tag="PC592_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HDF4055098.1"
                     /translation="MKNPLIVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIKDKSNKEEKNIVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            17928..18596
                     /locus_tag="PC592_001096"
     CDS             17928..18596
                     /locus_tag="PC592_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDF4055099.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVNVKKEQKITEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            18694..18954
                     /gene="spoIIID"
                     /locus_tag="PC592_001097"
     CDS             18694..18954
                     /gene="spoIIID"
                     /locus_tag="PC592_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HDF4055100.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19151..20170
                     /locus_tag="PC592_001098"
     CDS             19151..20170
                     /locus_tag="PC592_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF4055101.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20186..20614
                     /gene="fabZ"
                     /locus_tag="PC592_001099"
     CDS             20186..20614
                     /gene="fabZ"
                     /locus_tag="PC592_001099"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDF4055102.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(20725..21234)
                     /gene="yyaC"
                     /locus_tag="PC592_001100"
     CDS             complement(20725..21234)
                     /gene="yyaC"
                     /locus_tag="PC592_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HDF4055103.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      21423..21526
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            21662..22855
                     /locus_tag="PC592_001101"
     CDS             21662..22855
                     /locus_tag="PC592_001101"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDF4055104.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGIVDYLRPDGKTQVTVEYEGNKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEDTKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVASGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23168..24265
                     /locus_tag="PC592_001102"
     CDS             23168..24265
                     /locus_tag="PC592_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055105.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     VGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGIFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCILYRRITKTEGYKENKSEIS"
     gene            24529..26748
                     /locus_tag="PC592_001103"
     CDS             24529..26748
                     /locus_tag="PC592_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDF4055106.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKVYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIDVINKNPYQLAEDIRGIGFKVADSIANKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELSGKIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEENKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMISSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYVLFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPITWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            26751..27533
                     /locus_tag="PC592_001104"
     CDS             26751..27533
                     /locus_tag="PC592_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDF4055107.1"
                     /translation="MKICNDNFIKDFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIHHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKIVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYVLFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENIKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            27865..29778
                     /locus_tag="PC592_001105"
     CDS             27865..29778
                     /locus_tag="PC592_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4055108.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNEIANDFECSERTIRNDCKY
                     IDEWLSTFCNACIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEIGKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMFTIEENMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSSNIKKSLYLNEELANYTRKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            29919..30227
                     /locus_tag="PC592_001106"
     CDS             29919..30227
                     /locus_tag="PC592_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF4055109.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30252..30578
                     /locus_tag="PC592_001107"
     CDS             30252..30578
                     /locus_tag="PC592_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4055110.1"
                     /translation="MKRKVYLFCSFGMSTSLLAEKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            30618..31952
                     /gene="celB"
                     /locus_tag="PC592_001108"
     CDS             30618..31952
                     /gene="celB"
                     /locus_tag="PC592_001108"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDF4055111.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     SNFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSVHEFIFKFL
                     QIPLLKLGNTLSATAIAYVFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGT
                     KLPNIITAQFQDMFATFGGAGSTLSLIIAMLLICKSKRIKSIGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFALVPTVNIIIAYFCMSTGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLIILGIFMYIPFIKMLDKQYLKDEKSNVEGEDDDISFDDLVL"
     gene            31963..32481
                     /locus_tag="PC592_001109"
     CDS             31963..32481
                     /locus_tag="PC592_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HDF4055112.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEPFLNE
                     SKVIATLFCGDEFFINNEEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKADIPAFAAMSEENIDVINEYKNDICIVRTPKKGGIGLNDSLNNICKLAKAMANK
                     EDITLMKEEFCY"
     gene            32577..33536
                     /locus_tag="PC592_001110"
     CDS             32577..33536
                     /locus_tag="PC592_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HDF4055113.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEEYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            33585..34637
                     /locus_tag="PC592_001111"
     CDS             33585..34637
                     /locus_tag="PC592_001111"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF4055114.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKIRNLNNYIGYAEHGDSEDYVCVIGHVDVVHEGDGWKYQPYKGE
                     EINGRIYGRGVLDNKGPIISALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVLLGFIENVSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKFSFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            34640..35314
                     /locus_tag="PC592_001112"
     CDS             34640..35314
                     /locus_tag="PC592_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDF4055115.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIERV
                     VNSVKIPVNVMIRPHAKSFVYSKEDINIMQKDVSVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKTLKDYDKIINILTSGGKGSIVDNIQIIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRMNNSPFEDIDRQKLRQL
                     VNIISR"
     gene            35867..36418
                     /gene="raiA"
                     /locus_tag="PC592_001113"
     CDS             35867..36418
                     /gene="raiA"
                     /locus_tag="PC592_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF4055116.1"
                     /translation="MNIIISGKQIELTDAIKNKIESKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            36550..39225
                     /gene="secA"
                     /locus_tag="PC592_001114"
     CDS             36550..39225
                     /gene="secA"
                     /locus_tag="PC592_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF4055117.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPISKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39240..40347
                     /gene="prfB"
                     /locus_tag="PC592_001115"
     CDS             join(39240..39314,39316..40347)
                     /gene="prfB"
                     /locus_tag="PC592_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDF4055118.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNKQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEEDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            40492..42633
                     /locus_tag="PC592_001116"
     CDS             40492..42633
                     /locus_tag="PC592_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDF4055119.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAENYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKENFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVNSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DREVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHIAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIDEIDEKIKEIGLKELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMILKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            42781..43947
                     /locus_tag="PC592_001117"
     CDS             42781..43947
                     /locus_tag="PC592_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4055120.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIEEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPVDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTYGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIADELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVIYTIINGKVVYEKK"
     regulatory      44007..44124
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44248..44853
                     /locus_tag="PC592_001118"
     CDS             44248..44853
                     /locus_tag="PC592_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF4055121.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            45183..46223
                     /locus_tag="PC592_001119"
     CDS             45183..46223
                     /locus_tag="PC592_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF4055122.1"
                     /translation="MNLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENLERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKSQTEELCLEAIKYNYK
                     ALEYVKEQTEYICLEAIKKDCNALKYVRNKTEGLIIKVIRHSTNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVENQTEKMCIEAVKQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVDNKTEEICINAIRYLNKKYNIKDVLCYVDNYT
                     EDMCIEIVRQNGKMLMYIKNQTEKICIEAVKENYKSLKYVKEQSERICKEALKQNYKA
                     KEYVKIAIDDCI"
     gene            46362..46814
                     /gene="tsaE"
                     /locus_tag="PC592_001120"
     CDS             46362..46814
                     /gene="tsaE"
                     /locus_tag="PC592_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDF4055123.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIKDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            46814..47530
                     /gene="tsaB"
                     /locus_tag="PC592_001121"
     CDS             46814..47530
                     /gene="tsaB"
                     /locus_tag="PC592_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDF4055124.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTANNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     MNFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVIEFDALVEEIVSTNEEFIM
                     VGEAVYKYKDKLENIENIKIPSPANNVSKAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            47520..47996
                     /gene="rimI"
                     /locus_tag="PC592_001122"
     CDS             47520..47996
                     /gene="rimI"
                     /locus_tag="PC592_001122"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDF4055125.1"
                     /translation="MEDNINLIVNDIKIEEMTIEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLDGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48002..49018
                     /gene="tsaD"
                     /locus_tag="PC592_001123"
     CDS             48002..49018
                     /gene="tsaD"
                     /locus_tag="PC592_001123"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDF4055126.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANMDFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAQKGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDSGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            49315..52023
                     /gene="hpdB"
                     /locus_tag="PC592_001124"
     CDS             49315..52023
                     /gene="hpdB"
                     /locus_tag="PC592_001124"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HDF4055127.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLNEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTHHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKSVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLREDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52027..52284
                     /gene="hpdC"
                     /locus_tag="PC592_001125"
     CDS             52027..52284
                     /gene="hpdC"
                     /locus_tag="PC592_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HDF4055128.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDEACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            52277..53227
                     /gene="hpdA"
                     /locus_tag="PC592_001126"
     CDS             52277..53227
                     /gene="hpdA"
                     /locus_tag="PC592_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HDF4055129.1"
                     /translation="MSSQKKLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKAYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSSEVFNKIFEDIDFAFIDIKHMDREKHKEQTGVYNDLILKNIS
                     NLANSDWNGRLVLRVPVISGFNDSVKNISDIISFMHKNNLVEINLLPFHRLGESKWVQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(53335..53562)
                     /locus_tag="PC592_001127"
     CDS             complement(53335..53562)
                     /locus_tag="PC592_001127"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055130.1"
                     /translation="MYKKTNDNVYLYNLEKTLDEIFQLFDLSLRYSFKTFSNLETMEN
                     TSFLEGTSGIILLLISISSKDSTYKKLLFLS"
     gene            complement(53591..54385)
                     /locus_tag="PC592_001128"
     CDS             complement(53591..54385)
                     /locus_tag="PC592_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4055131.1"
                     /translation="MMILPLSSVAIAKFYTEGLNNDMYKFYSLIILFFLIYSLLIILR
                     LLNLINNSEFTIINLILTFISSLSIIIYSSNTKNLYPVKNIKAGSLLIIYFMISVIVP
                     TSFLLILQGTQPSYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDRFGKKLG
                     VIILGMCWSLWHLPLIFTLYTPETPILGLILRSIHIVGIAIFLGYLYMKTKNVWFCAI
                     IHILNNSAFLITNVEESIITYSDILIVSMVSLIFYVPFLFTKEYKG"
BASE COUNT        21991 a         5813 c        10338 g        16415 t
ORIGIN      
        1 gcggcctggt agttcagttg gttagaatgc cagcctgtca cgctggaggt cgagggttcg
       61 agccccttcc aggtcgccaa attaaataag cgggaatagt tcagtggtag agcgcaacct
      121 tgccaaggtt gaagtcgcga gttcgaatct cgtttcccgc tccataataa tttgggtgca
      181 tagctcagct ggatagagca acgcccttct aaggcgtgtg tccggggttc gaatccctgt
      241 gcgctcatta agaaaagttt actataattt atagtaaact tttatattgt ttaaaaagac
      301 acaggtaata tacatgtatc ctgtgtcttt ttatttataa actttaaact atgtaaaaat
      361 tatagtatat tctaatagag ttacagtata ttcattaatg ttgtaaacat atgaagggta
      421 atgtataata gtctacaagg tgtttatgaa ggcaatagtt aaatatgact aattggatag
      481 aaactatata cattatattg tatactttat ggtatttata aagagattca ttttgcctaa
      541 acaataagta taagaaatta tacaaaaatt agatactata atggattgac aatttaatgt
      601 aatgtttata agttatacta aataaattat tatactgtga agtatatata actttaggta
      661 ttgtgtatta ttttcactgt agaagattct atctagttat acatgatgag ttttaatgat
      721 agtttatagt aagatattaa aatatattta tctaatctag atatgaaatg agttattact
      781 ttaatataaa aatgaaccta atgaaacaat attgatgata agtaatactt aaattttgta
      841 tctgtatata gttgataaat gtattataga atttacaata attaatatat tttagagaat
      901 aaaattgcat taaggcgcga gtactacttt gtattcgcgc cttgatagct tgaattattt
      961 aagtaaaagt aattttaata aaaaataagt atttattaag ttgatatttt taatgtgttt
     1021 agagattatt taacaatctc taaatataaa actagaatta tttacataaa agttaaatag
     1081 tttgtataga gttagattta tatagtataa tacttagtgt aaataattaa gaagttatca
     1141 aacaggagga taaaactgtg ttagatataa attctttttt aaatggattt tttaatataa
     1201 tattaagaat gagtatatat gatttaattg acatatctat agtagcatat attttttaca
     1261 aaatatttat gtttataaaa gatacaagag cagaacaagt gtttaaaggt ataatatttc
     1321 ttttattagc aactcaactt agtaacacct ttaaattgca taccgtttat tggatatctc
     1381 ttaaggcttt agattatgga gttatagctg ctcttataat ttttcagcca gagtttagag
     1441 caggacttga acatatagga agagcaaagt ttaatttatt tggaaagaat gtaaatactt
     1501 ctgaagaaac tctcaataga aatatagaag aaattgtaga agctttatat tcactttcta
     1561 gacaaaaaat aggtgctctt atcataatgg agagagaaac tagaataagt gatataataa
     1621 atacaggaac tattattgat gctgaaattt ctaggcaact gttaataaat atatttatac
     1681 caaatacacc attacacgat ggagctgttg taattagaga ttctaaggta aaagcagctg
     1741 catgtttttt gccattgaca gaaagtaagg atttaagtaa agatttgggg actagacata
     1801 gagcaggaat aggagtaagt gaggtgtctg actgtataac cttgattgta tcagaggaaa
     1861 caggtggcgt atcaattgct aaagcaggta agttatatag agatatttct agagaaagaa
     1921 tgatgaatat attacgtagt aatttaaaaa caaatacaga aacaagaagt tttttcaaag
     1981 gtggtatatt taaatgataa acagattaaa aaataatacc aaaataaaaa taatatcatt
     2041 tttaagtgca attgcattat ggatgtatgt tatggctgta gttgaccctg aagaaactaa
     2101 agggtttgaa gatatacctg tatctataag taatatgaac gatttgaagg ataaaaatct
     2161 tgttatatat ccagacgaaa aattaacagc agatgtatat ataaaaggta gtttatcaaa
     2221 ggtacaaagt gttaagaaag aagatataca tgtacatgga actattgaag acccaataca
     2281 aggacagaag gaagtgtatt taaaagcaaa tattcctcaa ggtgttacta tagaatttaa
     2341 gcatgatgtt ttagtagtga atcttgaaaa aaatataaaa gaaaaaagag atataaaggt
     2401 agaagtaagt ggaaattcaa aaaaaaatat aaataaaatt gaacttagta aggaatttgt
     2461 cgatgtgtcg ggtccaagaa ctctagttaa agaagtcaaa agtgtaagag ctaatttaga
     2521 tgttggtaat gagacagatg atttttctaa aaaattgcaa ttaataccat taaatagtga
     2581 tggaactaaa gttgaaggag taacattaag ctcatctttt gtgactgcaa aaatagaact
     2641 gttaaaggaa aaaattgtcc caataagagt aaatctaaat gataataaag ataatgatgc
     2701 actgaaaaac tataaattaa gtaaggaaca agttacaata aaagggaaaa aagaagatat
     2761 agacaaaata aattatatta agacaaaacc tattgactta gctgatttgg ctaatggtga
     2821 agaaaaagaa gttagcttag aagttccaga gggtataact cttgagggtg cctctataac
     2881 aataaaatta aatgatacaa aacaattgag tgcagagttt ttatatagtg caggagatat
     2941 tgaattaaga aatatcccaa caaatatgga taatccaagt gtaatttctg atgtagatat
     3001 aaaagttgtt gtagagtcaa cagaagattt gagtaagtta aataaaaaag atatttcatt
     3061 atatattgat ttatcacaag gtcctgagga agatagtaaa tataaaataa aatatgaaac
     3121 aacatatcaa tttaaaaaaa taaatataga acctaatatt gttgaagtgg aatgaacaaa
     3181 tatttcgaat atttagttgt tacaagatgc gacaaaaaaa cctataaaat taagtttgtt
     3241 aattttatgt ttttgttgca tcttgtttat tttagttata ttataaaata aggacaatga
     3301 gatatttgtt aaatctaaaa agcgctagat atatgaaaaa agactgataa atagatttaa
     3361 ataaatattt tgaattaaat atttcaatta tctctaggaa aacgttgctg aacgagttat
     3421 aatttaattg agatataaaa agttctattt caaaaaattc aagatgaggt ggaaatgcat
     3481 gagaagtttt gaagaagtaa ttaagtttgc aaaagaaaga ggacctaaaa ctatatcagt
     3541 agcatgttgc caagataaag aagttttaat ggcagttgaa atggctagaa aagaaaaaat
     3601 agcaaatgcc attttagtag gggatataga aaagactaaa gaaattgcaa aaagcataga
     3661 catggatatc gaaaattatg aactgataga tataaaagat ttagcagaag catctctaaa
     3721 atctgttgaa ttagtttcac aaggaaaagc cgacatggta atgaaaggct tagtagacac
     3781 atcaataata ctaaaagcag ttttaaataa agaagtaggc cttagaactg gaaatgtatt
     3841 aagtcatgta gcagtatttg atgtagaggg atatgataga ttatttttcg taactgatgc
     3901 agctatgaac ttagctcctg atacaaatac taaaaagcaa atcatagaaa atgcttgcac
     3961 agtagcacat tcattagata taagtgaacc aaaagttgct gcaatatgcg caaaagaaaa
     4021 agtaaatcca aaaatgaaag atacagttga agctaaagaa ctagaagaaa tgtatgaaag
     4081 aggagaaatc aaaggttgta tggttggtgg accttttgca attgataatg cagtatcttt
     4141 agaagcagct aaacataaag gtataaatca tcctgtagca ggaagagctg atatattatt
     4201 ggctccagat attgaaggtg gtaacatatt atataaagct ttggtattct tctcaaaatc
     4261 aaaaaatgca ggagttatag ttggggctaa agcgccaata atattaactt ctagagcaga
     4321 cagtgaagaa actaaactta actcaatagc tttaggtgtt ttaatggcag caaaggctta
     4381 attttaaggg ggaaataggc aaatgagcaa aatatttaaa atcttaacaa taaatcctgg
     4441 ttcgacatca actaaaatag ctgtatttga taacgaggat ttagtatttg aaaaaacttt
     4501 aagacattct tcagaagaaa taggaaaata tgagaaggtg tctgaccaat ttgaatttcg
     4561 taaacaagta atagaagaag ctctaaaaga aggtggagta aaaacatctg aattagatgc
     4621 tgtagtaggt agaggaggac ttcttaaacc tataaaaggt ggtacttatt cagtaagtgc
     4681 tgctatgatt gaagatttaa aagtaggagt tttaggagaa catgcctcaa atttaggtgg
     4741 aataatagca aaacaaatag gtgaagaagt aaatgttcct tcatacatag tagaccctgt
     4801 tgttgtggat gaactagaag atgttgctag aatttctggt atgcctgaaa taagtagagc
     4861 aagtgtagta cacgctttaa atcaaaaggc aatagcaaga agatatgcta gagaaataaa
     4921 caagaaatat gaagatataa atcttatagt tgcacacatg ggtggaggag tttctgttgg
     4981 agctcataaa aatggtaaaa tagtagatgt tgcaaacgca ttagatggag aaggtccttt
     5041 ctctccagaa agaagtggtg gattaccagt aggtgcatta gtaaaaatgt gttttagtgg
     5101 gaaatatact caagatgaaa ttaaaaagaa aataaaaggt aatggtggat tagttgcata
     5161 cttaaacact aatgatgcta gagaagttga agaaagaatt gaagctggtg atgaaaaagc
     5221 taaattagta tatgaagcta tggcatatca aatctctaaa gaaataggag ctagtgctgc
     5281 agttcttaag ggagatgtaa aagcaatact attaactggt ggaatcgcat attcaaaaat
     5341 gtttacagaa atgattgcag atagagttaa atttatagca gatgtaaaag tttatccagg
     5401 tgaagatgaa atgattgcat tagctcaagg tggacttaga gttttaactg gtgaagaaga
     5461 ggctcaagtt tatgataact aatgataaaa gaataagaat cataactggt cactatggaa
     5521 gtggtaaaag tgaatttgcg atgaactatg ttgttaagtt aagagatatg gtttctggca
     5581 aagttgctat agccgattta gatgtggtaa atgtatactt tagaactagg gaaaagaaag
     5641 agttaatgaa atctttaggt atacaaccaa tagatagctc aattaatgct ccaacattag
     5701 atttaccagc agtatcagca gaggtgatgt ctcctatggt ggaccattca tacaattctg
     5761 ttatagattt aggtggagat aatgtaggtg ctagggttat aggaagattt agtcatttgt
     5821 taaaagaagg cgactatgat atgctttttg taataaatgc aaatagggag aaaactcaaa
     5881 cttctgaaga agttatccaa tatataaaag aaatagaaaa atcttctaaa ttaaaggtaa
     5941 caggtctaat taataatact catcttatta gatttactac tattgatgat gttttaagag
     6001 gtcagaaagt tgcaaaagaa gtttctgaaa aatgtaatat accaataaga tatgttgcat
     6061 gtttagaaaa tcttgttgaa cagttaccaa aagatttaga aggagaaatt tttcctataa
     6121 aattatatat gagagaagac tggatgtagt ttgagctcaa atatatagaa agtttaagga
     6181 ggcttaggta aatggctaaa ggaaaagtat cttttaatca agaacgttgt aaaggttgtg
     6241 gattgtgtgt tgaagcatgt ccagtaaaaa tcatacaatt agactcaaat gtaataaaca
     6301 aaaaagggta taacccagca actgtttttg aaatggaaaa atgcatagga tgtgcaagtt
     6361 gtgcaactat gtgtccagat gtagttataa cagtagaaag agattaattt aattaatatt
     6421 taagggggaa ttttaatggc taagatactt atgaaaggta acgaagcatt tggaaaagca
     6481 gctatagaag ctggttgcaa atatttcttc ggttacccaa taactccaca aagtgaatta
     6541 ccagaatatt tatcaagaga gttacctaaa ataggtggag cgttcgttca agctgaatca
     6601 gaagtttctg cgataaacat ggtttatggt ggagcaggtg caggagcaag agttatgact
     6661 tcttcatctt caccaggagt tgctttaaag caagaaggaa taacatatgc agtaggagca
     6721 gaagttcctt gtgttgtact taatgtaatg agaggtggtc caggacttgg aagtatacaa
     6781 ccttcacaag ctgactactt catgtctaca agaggtggag gaaatggaga ctacagaact
     6841 ccagtattcg caccagctac agttcaagaa gctgttgata tgataatgga agcttttgat
     6901 gttgcagatt attacagatc accagttatg gtagttgcag atggtatgat aggtcaaatg
     6961 atggagccag ttgaatttag agctcctgag aagaaaagag aattgcctcc taaagattgg
     7021 gcaactgttg gaactaaagg aaaaagaaaa cctaatgtaa taaactctct atacttagag
     7081 ccagaagtac tagaagacca ttgttggcat ttacaagaaa aatttgatgc aatggaaaaa
     7141 aatgaagtac aatatgaaat gtacaaaaca gaagatgctg aatttgtatt tgcagcttat
     7201 ggaactactt caagagtagt aaaaagtgca attgatatat taagagaaga aggaataaaa
     7261 gcaggtctta taagacctaa agtattatgg ccattcccat tcgaagcatt caaccaaatt
     7321 cctaatgcta gaaacatatt gactgttgaa atgagtatgg gacaaatggt ggaagatgtt
     7381 aaaatggcag tagaaggtag attaccagtt tacttccatg gaagaccagg aggaatgact
     7441 ccaacaccag cagaaatagt tgaaaaagct aaaaaaatta ttgccggaga attggttgca
     7501 ggaggtgcta gataatggct gttgtattta agaaaactga aggattacaa gatactcaaa
     7561 ctcactactg tccaggatgt acacatggta taatccatag attagttggt gaagtgttag
     7621 aagaactagg agtattaggt gatgctgtag gtgttgttcc agttggatgt tcagttttag
     7681 gatataaata ttttaactgt gacactcaag aagctgctca tggtagagca ccagctgctg
     7741 ctacaggaat aaaaagagtt catcctgaaa atacagtatt cacttatcaa ggtgatggag
     7801 acttagcttc aatcggtact gctgaaatag ttcatgcagc tgctagagga gaaaaaataa
     7861 ctactatatt tgtaaacaat acaacttatg gtatgactgg tggacaaatg gctccaacta
     7921 cattagttgg acaaagagct actactgctc aatcaggaag aaatgctgaa actcaaggat
     7981 atccaataag agtaagtgaa atgttagcta cattaacagg agctgtattt gtagaaagag
     8041 tagcagttga tactccagct catgttagac aagctaaaaa agctataaag aaagcattcc
     8101 aagttcaaca agcaggatta ggatttggaa tagtagaagt attatctact tgtcctacaa
     8161 actggggact agctccaaat gatgctttac aatggttaag agacaatatg ataccatact
     8221 atccattagg aaatttcaaa aatgttgaag ttgaggaggt gaagtaaatg tctacagcta
     8281 gagtaatatg tgcaggcttc ggaggccaag gtgttatgtc tatgggacaa ttacttactt
     8341 atgcagggat gctagaagga aaagaagttt cttggttacc atcttatgga ccagaaatgc
     8401 gtggaggtac agcaaactgt gcagtaactg tatctaatga accagttggt tctccactta
     8461 taacagatga tgcaactgca gctatattat taaatatacc agcatttgaa aaattcaaag
     8521 atgatgttat tcctggtgga aaaataatag taaatagttc tttaataaaa gaaaaagttg
     8581 atagaacaga tgtagatgtt tattatatac cagcaaatga attagcagct gaattaggaa
     8641 atgataaagt tgctaatatg ataatgttag gagcttactt aaaagtatct gatactgtag
     8701 atatagaatc tgtactagaa gcattcaaaa aagttttcgg acctagaaaa gaaaaattcg
     8761 ttccgttaaa cagagaagct ttacaaaaag gtatggatgc tacatgctct aaagcaacta
     8821 actaataaag aagaaaagat gtcaaaaaaa agacaataga attatttcta ttgtcttttt
     8881 tgctgataag tattaaaata tttttatgac tgaaattaag cctataatga tattttatga
     8941 actataaaaa tataatacaa attacaagct tttcaattat gaaaggagaa tctttagtga
     9001 gaaagtattt tggaacagat ggagttagag gagtagcaaa tacagaacta acatgtgatt
     9061 tagcatataa acttggtaga gctggtgggt ttgtcttagc tcaaggagac cacagagtaa
     9121 aagtagtagt aggtaaggat actagaatat caggtgatat gttggaagca tctttaatag
     9181 caggacttat gtctgttgga tgtgatgtta ttactgttgg aataatacca acacctgcag
     9241 tggcatattt aactagaaaa tatggtgctg attgtggtgt ggtaatatct gcatctcaca
     9301 atcctgttga atataatgga atcaaattct ttaataagaa tggatataaa ttagatgatg
     9361 aaattgaatt gaaaatagaa gaatatatag atgatataga caaaattgat tgtatgccaa
     9421 ttggtgaaaa tgtaggaaga aaattacatg agcattgtgc acaaagagat tatgtagact
     9481 atttaaaatc aataataagc actgacttta aggggttaaa agtagtttta gactgtgcta
     9541 atggtgcgtc atataaagta gcaccaatag tgtttgatga attaggagca agtgtaattt
     9601 caataaatag ttcaccagat ggaaataata taaactataa atgtggctct acgcatccag
     9661 aacaacttca aagtgctgtt ttggaacata atgctgactt aggtcttgca tatgatggag
     9721 atgctgatag attaattgca gtaaatgaaa agggtcaaat tgttgatgga gaccatataa
     9781 tgatattgag tgccttaaat ttaaagaaaa ataataaatt agcacaagat actttggtag
     9841 ttacagttat gagtaatata ggattaacaa tagctgctaa ggaaaatgga ataaatttat
     9901 ctactacagc agttggagat agatatgttt tagaagatat ggttaaaaat ggatataatc
     9961 ttggtggaga acaatctgga catatgatat ttttagatta caacactact ggagatggag
    10021 tgcttagttc tctaatactt gcaaatataa tcttgcaaga aaagaaacct ttatcagaac
    10081 ttgcatcaat aatgagtcaa tatccacaag tattagtaaa tgcaacaata aaaaatgaaa
    10141 ataagaacaa atatatggaa tatccagaaa taaaaactga gatagaaaga atagaatcta
    10201 ttttagatgg aaatggtaga gttttgataa gaccatcagg aactgagcca ttagttagag
    10261 ttatgttaga gggtaaagag gaaggtcaaa taaaagaatt agcaacaaat ttagctaatc
    10321 ttatacaaga aaaattatcg taatttaaag ggtattctca gatataaata ctgaggacac
    10381 ctttctaagc gccagaactt agttatagac ataattattg agtaatatag gaactaagtt
    10441 gacgaggtca gagttaatcg aattgtcggc ggatgctctg cggtgtgttt accatcgaaa
    10501 gacttcttta aataatagga gtaatcctat ggacaaaggg aagccaaagt aaacttatat
    10561 gacctaactc ttaaaatata taaataatat ttttaggagg acacaaataa tgtgtggaat
    10621 agttggatat ttaggaagta gaaaggcagc agaagttata gtagaaggac tttctaagct
    10681 agagtacaga ggttatgact cagcaggagt agcagttaat agttctaatg aagaagaact
    10741 taatattaga aagtttaaag gtagactttc tgtacttgca gaagatttag aaaagaaccc
    10801 tattgatggg aatttaggga tagggcatac aagatgggca actcatggag aaccatctga
    10861 tgtaaactca catcctcatt ttaatcaagc caaaacaata gcagttgttc ataatgggat
    10921 aatagaaaac tatatggaaa taaaagaaga attagtttct gaaggtgtta aatttgaatc
    10981 tcaaacagat acagaggtaa tagcacattt agtagataaa tattatgagg gtaatttatt
    11041 agatgctgta tacaaaacta tatcaaaatt aagaggagct tatgcattag gtgttatatg
    11101 taaagaacat ggaaatgaat tagttgcagt aagaaaagat agtcctcttg tagttggtgt
    11161 tggtgaaggt gaaaacttta tagcatcaga catacctgca ttattaaaat atactagaga
    11221 tgtttatttc ttagaaaatg gagaagtagt tcatctaaaa gacgaaaatg taacagttta
    11281 tgactctaat agaaatcttg tggaaaaaga agtatttcat gtaacttggg atgtagaagc
    11341 tgcgtctaaa ggtggatatg actacttcat gtcaaaagaa atccatgagc aaccaacagg
    11401 agttagagaa actttagaaa gaagacttga tgataatgga aatatagtct tagacagtat
    11461 aaatatttct aaagaagatt tagaaaagat aaataaagtt tatatagtgg cttgtggaac
    11521 agcatataat gctggattac ttggtaagta tgctatagaa aaatttgtaa atataccagt
    11581 aataactgat atagcctcag aatttagata tagcgaccca tttgtagatg aaaattcatt
    11641 agtaatatta gttagccaat ctggtgagac agcagatact ctagcagtat taagagattc
    11701 aaaggctaaa ggagcaagaa tactttcaat aactaacgtt gtaggttcat ctatagcaag
    11761 agaatcagat gatgtattct atacttgggc aggacctgaa gtagcagttg catcaactaa
    11821 ggcatatact actcaaataa cttctttata catgatagct ttagactttg ctatcaaaaa
    11881 aggaacaata actagagaat tttatgatag tatgatttct aagatgaaag acataccatc
    11941 aaaaatacaa gaaatactag acaatgaaga atatataaaa gaagttgcta aaacagttgt
    12001 taattctgac cacgcattct atttaggaag aggtatagat tatagcttag caatggaagg
    12061 ttcattgaaa ttaaaagaga tttcatatat acatgcagaa gcttttgcag caggagagct
    12121 aaagcatgga acaatagctt taatagaaaa aggaactcct gtaattgcca tagctactca
    12181 agaaaagtta tttgaaaaaa tggtttctaa tatggaagaa gtaagagcaa gaggagctta
    12241 tgtagtagca atagctcaaa gccataataa ggatgttgag aaagctgctg ataaaataat
    12301 ctatatacca aattcagatg atattttatc accaatatta gcagttgtac caatgcaatt
    12361 acttgcttat catgtctctg tattaagagg atgcgatgta gataagccaa gaaatctagc
    12421 taaatcagta acagttgaat aaaaatagat taaaaattaa atagataata tttattgaaa
    12481 aaaactcatc ctgttatttg tattttatag gatgagtttt ttagataaat attaaatttg
    12541 ttttgttttt gctataataa attttataaa aagattgaat taaatcatct gtaaaatgat
    12601 aaatatatag accatataag gtatagagaa taataaatat atagttcata taaagtatag
    12661 tgagtactta ataaacatat agtcgatatc agatatagtg aatacttaat aaacagatag
    12721 tcaatataag acataaaaaa tactagatta tgagaaagat taaaatacat aaggtattag
    12781 taaccttgtg ataaaataaa gtgagtagtt taaaataaaa atataaggaa ctatttataa
    12841 aagaatataa tgaagctaat agagtataag aaaattactt tattttacta aaatgatttt
    12901 aaataaaaaa tttttaaatt gggagtataa attatggcaa atgattttaa aaaagaaaag
    12961 aaagaagatt attttgttaa tcttaaggca atatctactg aagttttaca agaaaaagtg
    13021 caagataacg cttgggttat agttgatact cgcttaaatg atgcttataa tggctggaag
    13081 ttagatggag taaaaagagg tggacatata aaaggagcag tagatttttc tgctaattgg
    13141 ttaagtgtat actcagataa aaaagatgaa gtgctagaac aagcattgaa aactaaaaga
    13201 attgatatag ataaaaatat agtattatat gatgcaaatg gaaaagatgc tttggttgta
    13261 gcagattatt tatctaaaaa aggatataaa tatctatata aatatgatat taaacaatgg
    13321 gcagacaacg aaaatcttcc aatggaaaga tataaaaatt atcaaatgat agttcctgct
    13381 tttataataa aagatatatt ggatggaaaa attcctgaga catttgaaaa ttccaagaat
    13441 ataaaaatga ttgaagcgag ttggggagaa gaatcgtata caaaagggca tatacctaca
    13501 agtgttcatg taaataccga tattatagaa cctcctccaa catggatgct tgataatgat
    13561 gataacttga ctaagtttgc tttagactat ggattcacaa aggatgatac tgtaatagtt
    13621 tcaagtagta cacctatggc atcttataga ctagctgtta tattgagata tataggagta
    13681 aaagatgtaa gagttttgaa tggcggaaca aactcatggt tatcagcagg atatgaatta
    13741 gaatttacta gtaatccaaa acattcatgt actaattttg gagcagatat accagttaac
    13801 tcacaattag ttgttactac atctgaatta agacaaaaac taaaagaaaa aaataagttt
    13861 gtactagtag ataaccgtac ttgggatgaa tatataggaa aagtatctgg atatacatat
    13921 tatgataaaa aagggcgtat accaggagct ttatatggac attcaggtag tgatagtgtt
    13981 tcactagaag aatatcgtaa tattgataat acaatgagaa ataaatatga gattctagaa
    14041 atgtgggaca aggaaaatat agatgtgaat aaacagctta tatttatgtg tggaagtgga
    14101 tggcgtgctg ctgaagtatt aacatacgca aatgtcatag gagtggaaaa tacctcactt
    14161 tatagtgatg gatggatggg ctggagtctt gataattcaa atttaattga agtgggagaa
    14221 cacaaataaa gtttttgaaa gtacgataga gttatttaaa acaaaggtgt ttttgattta
    14281 ttaggaagag tatgtaaatt gtgttttggg aagtgtactt aggtatgttt atttggagct
    14341 atggaaattg ataaaaaagt attatctgtt tattttgctg gtaaaatgtg aatagattat
    14401 agattataga ttatagatta tagattatag attatagatt atagatttag gtatagacta
    14461 agtaatttat attacagaag agaatatata agaactagtg caagatgtat ttgatacata
    14521 taaaaaattg gcaaatccag aagaaggata gagaaaattg agattgaaga gtttgaaaga
    14581 gccttattag atgaaaaata caaagatgta taaaaataca tattgagaaa gtatatctct
    14641 cttaaatttg ttaataattc tattatacag aaaaacatgt ttaaggggga ttttttacta
    14701 tgaaaagagt aaaattagct ataagctttt ttatattaat gattatagga atgacaatat
    14761 cttatgcaga tactagtata aatactagat acaatagatt aagcaaagct cttgaaattt
    14821 cagaagcaaa ttttaaattt tataatatta aaattaattc tgttataaat cataatttat
    14881 caaataaaga attttataat atttttatag aaataattaa caatctaaag ttggataaaa
    14941 aaggaataaa ttggaatcga aaagggtctg gcgataaaat acaattatgt gctactataa
    15001 aaggtagcga taaagaaatt tctataaaag gaataaataa aaataacaaa gaaagttaca
    15061 tagtagttga catattggat aacaaagtat ataaacataa agaggttatt tatagtaacg
    15121 tagaaaatgt gttaaataaa tattcatctc aagtagatgt gtctgcttgt attgttggag
    15181 aatacacaaa aaggttacaa aacaacaaat atgatgatat tttacaaaaa atattatata
    15241 atatgagtgc taagcaaata gatgaagtga aagacgtaaa ctttttatct ataacagcat
    15301 atagtaaagt attaaatgat tatgaattag aatatttagg ggaaaaaatt aatttaaata
    15361 taggaattaa atataatgag gacgacggaa gaacactcat atatattgcc acaccaatta
    15421 taaaattaga ttattaatta tgaggagatc aaaaaatatg gctaagataa tagtaaaaaa
    15481 gagtaatcca cttaaaggta gtgttaaaat agatggtgca aaaaatgcag ttttaccaat
    15541 aatagcagcg actttattag caaacgggaa atcaacatta aatggagtac caaatttaag
    15601 agatgttcat gttatatcag atttattaag acatgtaggg gcagaagttg aatataaaga
    15661 aaatacactt actgttgatg caagcaatat aaaaacttgt gaagctccat atgagcttgt
    15721 aagaaagatg agagcttctt ttttggttat ggggccatta cttgctagat ttaatagtac
    15781 gaaaatttct atgccaggag gatgtgctat aggaacaaga cctatagatt tacatttaaa
    15841 aggatttaaa gctttaggtg caaaaataga gatggaccat ggttttgttg aagcagcaac
    15901 agaaaaatta gtaggaaata aattatattt agattttcca tctgttggag caactgaaaa
    15961 tataatgatg gcagcttctt tggcagaagg aactacaata atagaaaatg cagcagaaga
    16021 gccagaaata gtagatttag caaacttctt gaatgaaatg ggagcagatg ttaaaggagc
    16081 aggtactaat actataaaaa taaaaggtgt taaagagcta aaaggagcag aacataatgt
    16141 aattccagac agaatagaag cagcgactta tatggttgca gcagccatga caaaaggtga
    16201 tataactgtt gaaaatgttt taatggagca tttaaaacca gttgtagcta agttgagaga
    16261 agctggttgt gaaataacag aaatggacaa ttctgtaaga gttgtaggtc caaaggtatt
    16321 aaaaccaata gatataaaaa ctttaccaca tccaggattt cctacagatg ttcaagcaca
    16381 atttatggct atgcttactg tagctaatgg aactggtgta gttatagaaa ctgtttttga
    16441 aaatagattt atgcatgttg ctgaatttaa tagaatgggt gctaatataa aaatagatgg
    16501 aagaagtgcg gttgttaatg gtgtagatga gctacatggt gcagcagtaa acgctactga
    16561 tttaagagca ggggcagccc ttattttatg tggtcttata gcagaaggag aaactcaaat
    16621 aggagaaata taccatatcc aaagaggcta tgttgatata gataagaaga taacggcatt
    16681 aggtggtcaa atcgaaatag tagaagatta ataattggtt tatagaagaa agttataaat
    16741 taatagggtt gttcatatac ttaaatacaa ggttttaaaa gctaaggagg agagtatatg
    16801 aagaacccat tgattgtttt gctaggattt gtaacttgct ctgtgttagt tccatcactt
    16861 ataactttag tttcttataa aaatgtagaa ttaactgaaa aaccagagag cccagtatct
    16921 ataaacaaaa ctattaaaaa aagtgatatt aaagacaaaa gtaataaaga agaaaagaac
    16981 atagtgaact atgaaactgt aaataaaaaa gcaccaatca tcaatgtata taatcatata
    17041 acaggaaaaa ccgaaaaaat ggacatggag aattatttat gtggagtatt agctggtgag
    17101 atgtcttcag agtttgatat agaggcttta aaagctcaat ctgtagcagc tagaacatat
    17161 gtagtatata aacaggaaca tggtaaatca agtaaacata aaaatgcagt agtatgtact
    17221 gattataaac attgtcaaga atataagagt tatgatactc ttaaaaaatt aaatggtgaa
    17281 gaatggatta agaataaata ttccaaaatc caagaagcag ttagaggaac taaaggtcaa
    17341 ataataactt ataatgataa agcaatactt cctctttatt tttctacatc ttcaggaaaa
    17401 acagaaaata gtgaagaagt attttctgca aaatatcctt atttaaaatc tgtggaaagt
    17461 ccttatgata agtattcccc taaatttgca tcaacactta aaataagtaa cacagatttt
    17521 gttaagagtc ttagaagggc atatagcact attgttatag atgtgaataa tttaagtaaa
    17581 caagtctcaa taactaaaag aagtgatgct ggaactgtgg aaaaaataaa attaggaaat
    17641 aaagaattga ctggaaaaga cattagaact gtttttaagt taaactctgc aaactttgac
    17701 ataaaatttg gagaaggata catagacttt gtagtaaaag gatatggtca tggtgttggt
    17761 atgagccagt ggggagcaga aggaatggca gaagagggct ataaatatta tgatatatta
    17821 tcacattact acacagatac aaaaataaaa gatatatact aataattgta taaaatgcca
    17881 aaaacacgtc aataatccaa atgtagaaat atatttggag gtgcaaaatg aagaaaaagc
    17941 tgttagaaaa agatggtttt tatttatctt tgtttgtatg tgtttgttta ttagcagtag
    18001 gtggagtttg gtttacaaat aataatgtag ataaattggc ttctaataaa ggaataatgg
    18061 aaaatgctaa taaagatagt gaagaggaaa tacatttaat tgaaaaagac aagaaagatg
    18121 ctatccctac tgcaactgat tcaaaacaaa acttagaaaa agctaaatca aaagaggaaa
    18181 ataaatcgag tacaacaaaa ttaaattaca ttggagataa agtaataaga ggatattcag
    18241 aaaaagaacc tagttattct aaaacacttg atgtttggga aactcataaa ggtgtagata
    18301 ttagttgtac taaaggcaaa gaagtaaaat ctctattaaa cggaatagta gtagatgtat
    18361 ttaatgatga agaatatgga caatcagtca agataaaaag tgataataac attgtagtag
    18421 tatattcaaa tctagataaa aatgttaatg ttaagaaaga acagaagata acagaaggac
    18481 aatctctagg cactgtaggt agtacttctc aaatagaaag tgaagaaggt atacatgtgc
    18541 atttagaggc atatagtgga gaaaaatcta tagacccaat gagtctaatt aagtaaaagt
    18601 ataacaagtt taatcatatt tggttaagct tgttatattt tttggtgttt ttacatatat
    18661 atcattaaag ctattatgtg aggggggtaa tctttgagat ctcatataga ggaaagggcc
    18721 atagtggtag caaaatatat acttgaaaaa aacactacag taagacaaac cgccaagaca
    18781 tttggagtaa gtaaaagtac aattcataag gatgttacag aaagattgaa ggaaataaat
    18841 ccatcccttg ccaaagaagt taaaaatgtg ctagacaaaa ataaatcaga gagacatatt
    18901 agagggggat tagcaacgaa attaaaatat gagaaagaac ataaaaaaat gtaggttaaa
    18961 aacctacttt ttttatttaa ttaaattata aaaagaaata tattaagtaa ttataaatag
    19021 caaaataata atactctcaa aagatttatt ttctcttgat taaagcgaca tttttgtata
    19081 tgctttatta taggagtatt aaaataggct tataatataa tctaatatta taaataaagg
    19141 agttgaaaga atggctggag ctgatatagg catagattta ggtactgcaa atgtgcttgt
    19201 ttatgttagt ggtaagggaa tcgttttaga agaaccatct gttgtggcga tagacaaaag
    19261 aacagattct gttttagctg tgggagaaga agctaaaaag atgataggaa gaacaccagg
    19321 taatatagtc gctataagac ctttaagaga tggtgtaatt tcagattatg atgtaactga
    19381 gaagatgtta aaatctttta tagataagat agttgataaa aagggatttg gaagattttt
    19441 tatgccaaga attatggtat gcgtaccaac aggtgtcaca gaagtggaaa aaagagcagt
    19501 agaagatgct acgagacaag ctggagctag agaagtatat ataatagaag aaccaatagc
    19561 agcagccata ggagctggtg tagacatatc acagcctaat ggtaatatga ttatagatat
    19621 tggtggaggt actgtagata tagctgtaat atctctagga ggagctgttg taagtgaatc
    19681 tataaaggtt ggtggagata gatttgatga tgctatagtt aaatatatga aaaaacaaca
    19741 caatcttctt ataggagaaa gaacagcaga gaaaatcaag tttgaaatag gttctgcatt
    19801 taagagagaa gaagaaaaat atatgaagat aacaggaaga aatttaatta caggacttcc
    19861 tagttctata actataaatt caacagaaat gttggaagca cttagagaat gtgttgagca
    19921 aatagtagtt gctactcatg ctgttttgga aaaaacgcct cctgagttag cagcagatat
    19981 aggggatgtt ggtataataa tgactggagg aggttcatta ttatatggat tagataaaat
    20041 aatagaacag agaacaggaa taactgttac aatagcagat gaaccattat cttgtgttgc
    20101 aaaaggtaca ggaatagctt taggttcaat agacctactt gaaactggtg ggtctttcaa
    20161 aagaaaataa ttaggagagt ttagaatgtt aaatatagat gaaataaaaa aattaatacc
    20221 acatagatat ccgtttttat tagtagacaa gattacagag ctagaagtgg ggaaaagggc
    20281 tgttggtata aagaatgtaa cagttaatga accatttttc caaggtcact ttccagaata
    20341 tcctttaatg ccaggagtac taatagtaga agctctagca caagtgtgtg gagtggcaat
    20401 gatgtctgta gaggaaaaca aaggaaaatt aggtgtattt gcaggtatag ataaagttag
    20461 aattaagaga gaagtaagac caggagatac attaactatg gaagttgaaa tgacaactct
    20521 tagaaaaaac atagccaagg cagatgctaa ggcatatgta ggtgaagaac ttgtctgtaa
    20581 aggtgaatta atgtttgctt tagtagaaaa ataagaactt aaaatataaa agtaaaaagg
    20641 tagataattt ggagtattta ataagatact ctaaaatatc taccttttta tataaagaat
    20701 tttatcattt agtttatatt gggattaggt ggatactaat aaagccaagg ctattgtttc
    20761 agctaaatcc aatataaagc taagacgtat attattaaat gaaagtttat tattttcatc
    20821 aattttatct acaattccta ctatagaata atttcctatt tgaggtagtt ttttgccaac
    20881 accttttccg ggcaggatag gtccttctct aatctgtata ttacctatgt tactctgcga
    20941 ccccaagcaa gcatctatag ccaagaagtt accttgtata tgtgtatttt ttatagtatc
    21001 tagagactca tatatattta aggcgtgaat agggttatct agtgtaccgt aaacggggta
    21061 tttaaagtta ctgttcttaa gtattgttcc aactaaaggg cctaaagtat cacctatagc
    21121 cctgtctgtt cctatgcaaa caacaatcgt attttcatta attatagttt ttagaactga
    21181 acttagcatc tgtataacat catcatcgct gtaatttact ttagctaaat acaataggaa
    21241 cacccccttc aaaaaaatat atgaataaaa agcattaaaa agacctaact ttaaatttca
    21301 gatagataga aacttttatt tgtcttacaa aaaaaggaat agaaaaaata tgactaaaaa
    21361 tattgacaaa attttaaaaa aatagtaagc tagtaaagta aaacaaaact taaatcttga
    21421 ttaccttatc aagagaggct gagggatagg ccctgtgaag cccagcaacc acccaaatgg
    21481 gaaaaggtgc taattcctac aagacaagag tcttgaaaga tgaggtcagt taattagtat
    21541 gtaattacga ttattaacct cttcttataa aggagaggtt ttttattttg agtaaatttc
    21601 taaaattaaa aataaggtaa aacctataat aaaaactaag aataaacaag ggggaataaa
    21661 aatggcaaga catttattta cgtcagaatc agttacagaa ggacatcctg ataagatatg
    21721 tgaccaaata tcagattcaa tattagatgc attattagaa aaagacccgc aatctagggt
    21781 agcttgtgaa actacagtta ctactggttt agttttagta gcaggagaaa taagtacatc
    21841 tgcttatgta gacattccta aattagtaag agaaacagta agagaaattg gatatacaag
    21901 agcaaaatat ggatttgatt gtgatacttg tgcagttata acttctattg atgaacaatc
    21961 tggagatata gctatgggag ttgatgaagg tctagagagt aagactggag aagagataga
    22021 agaggaaata gaaaaagttg gagctggaga ccaaggtata atgtttggat ttgcatgtaa
    22081 tgagactcca gaattaatgc cacttccgat atctttggca cataaattat caagaagact
    22141 tacagaagtt agaaagacag gtatagttga ttatttaaga ccagatggaa aaactcaagt
    22201 tactgttgaa tatgaaggaa ataaagctgt aagagtacat acagttctta tatcagctca
    22261 acattgtgaa acagtatcaa atgataaaat aagagaagat ttaattaatc atgttattaa
    22321 agaggttata ccagcagaat tacttgatga agatactaaa atttatataa atccaacagg
    22381 aagattcgtt ataggaggac cacaaggaga tacaggtctt acaggaagaa aaataataat
    22441 agatacttat ggtggatatt ctagacatgg tggaggagct ttttcaggaa aagaccctac
    22501 aaaagttgat agatctgctg cttatgccgc tagatatgtt gcaaaaaata ttgttgcatc
    22561 tgggcttgca gataaatgtg agatagaact tgcatatgct ataggtatag ctagaccatt
    22621 atctatattt atagatactt ttgggacagg taaagtttca gaagaaaaac ttgttgaatt
    22681 agtaaataaa cactttgatt taagaccggg agcgataata agagacttag atttaagaaa
    22741 gcctctttat aaaaaagttg ctgcttatgg tcactttggt agaactgata tagatttgcc
    22801 ttgggaaaga actgacaaag tagagcagtt aagaaaagat gctttaggtg aataattttt
    22861 aactaaaaag ctgttagaat gtaattttac aattactttc taacagcttt ttattatgag
    22921 ttaaatattt ttaataaatg ctaatttatc atcatataat acataaacag tatttaatct
    22981 ggtcaataca ttttttataa taatctacta aatttataaa tattatgaga tatatgttaa
    23041 aggatggtta agaatgtgtt aactaatgtt aaataattaa aaatatattg aaatatcata
    23101 ataatgagtc taatataatc ttaataaact tacactttaa aataatttta attgggggga
    23161 gtagtgtatg tcaggtaaag taaatattaa aacggttata agttttgctg gagcttatgt
    23221 tgctactgta ataggttctg gatttgcaac tggtcaagaa atactacagt tttttacgtt
    23281 ttatggatat gctggtattg taggtggaat aatatctatg gtactatttt catggtttgg
    23341 agcagaagtt atagataagg gaagagaatt aaaacttaag gagccaataa aaatttatca
    23401 agtgtattgt ggaaaatacc ttggaatatt ttttgaatgg tttggtccat tgtttttatt
    23461 tggaacatta gtaataatga ttgcaggagc aggagctaca ttatcagagt actatggatt
    23521 aaatccatat gtaggtagga ttggtatggc aatcgtttcc ctaataactg tttcattagg
    23581 tttaacaaga ctttctaaaa tactaggtaa tataggccct ataataataa tatttacact
    23641 tttggtagga gcaattagtt tatttagcaa tattgatgct ttatcaaatg ctggaaatat
    23701 ggttgatagc ttaaatatta aaactgctac atcaaatgga tacttttcag gagtacttta
    23761 tacttgttat aatgtaataa tagtaataac attcttgaca ggaatgggag cttctgcagt
    23821 aaataagaaa gatgctgttt ggggtggtat agtaggtgga gtagcactta tggcagctgc
    23881 tataatgatg aatttggcac tactttcaga cataggaaac atatacacaa aagagatacc
    23941 agcactttac ttagctgata agatatctcc aataataggt attttattct cagtagtact
    24001 tttactagga atatacacta cagctgtacc attgttatgg tcagtaacta acagatttgt
    24061 agaagatgac caccctaaat ttaaaattat aacaatagta gtaagtatat tagcttgtat
    24121 aggaggtcta ctaccatttg ataagttagt aggtacacta tatccatata caggttacat
    24181 gggaatttta attttactat gtattcttta tagaagaatt actaaaaccg agggatacaa
    24241 ggagaataaa tctgaaataa gttagcactg taatattctt atgaaattta atttatactc
    24301 taaacataga gtaattaaaa taaaatagat atttaaatat ggtacctgta tttcatggta
    24361 ccatatttta tggatgcaga ttttttttgt ttctgataaa atgtataata gttggaaatt
    24421 acgttaagta taaaaatata aaacttttct aagattatca tagttttaat atataaaatt
    24481 atactaacat ttaaatggag cgattattag tatttttagg agataaaaat ggaaaaatta
    24541 gaaggaatga taagtgaaat agtctttaaa aacgaagata atggctatac aatagctcat
    24601 ctggtaaatg aaaatgatga gattgtcgtt gtaggatgta tgcctacttt ggcaattgga
    24661 gaaagcatag aagttgaagg aaagtgggta aaccataagg tttatgggac tcagtttgaa
    24721 gtgaatagtt ttatgccagt aacaccatca tccttagaag gaatttatgt ttacttatct
    24781 tctggaatga tacatggtat tggtgaaaaa atggctaaga gaataattga taagtttggt
    24841 gtagatacgt tagaggtgat acaaaattca ccagaaaaac tacaagaagt agaaggtata
    24901 gggagtaaaa aagtaaaaca aatagtaaaa agttatgaag aagacagaga attgagaaat
    24961 ataataatac agctatctcc ttttggaata acaccaaatt actgcctaaa aatatataaa
    25021 aaatataaaa gcagtgcaat agatgttata aataaaaacc cataccaact tgctgaagat
    25081 ataagaggaa ttggatttaa agtagctgat agtatagcaa ataaaattgg tatagataaa
    25141 aactctaagg atagaatttg tcagggtatc ctatacactt taaataaatc tttaagtaat
    25201 gggcatacat atttaccaga gcatgttcta atacaagatt cggaaaaatt attggagcta
    25261 agtgggaaaa taataaaaga gtgtgtaatg atgctagttt ataatcaaaa aatacatata
    25321 gagaaagtaa acaatgaaaa tctcatatat cttatgccat actatctagc tgaaaatgga
    25381 gtatgtagtc aaatagtaaa attatcacag tatgaatttg aagacttaaa aatagatata
    25441 gataacgaga ttaatgtttt agaagaaaat aagaaaatta agttagcaga aaaacaaatt
    25501 ttagcagtca aagaatctgt taatagtgga gtattaatta taactggtgg gccaggaact
    25561 ggtaaaacaa ctactatcaa tgctattata gacatatttg aaaacaatgg taaaagcgtg
    25621 actttggcag ctccaacggg aagagcagca aagagaatga gtgaaacttc taataaagaa
    25681 gcaaaaacta tacatagatt gctagaaatg ggattctcaa cagatgatga tttaactttt
    25741 tttaaggatg aagaagaccc aataaattca gatgtaataa ttgttgatga ggtatcaatg
    25801 gtagacatta ttttaatgta caacttgctt agagctataa agttaggaac aagagtaatt
    25861 ttagttggag atagtgacca attaccctct gtaggtgctg gaaatgtact taaggacatg
    25921 attagttcta atattataaa tgtagttaaa ttaaacgaaa tatttagaca agcgcaagaa
    25981 agtatgataa ttgtaaatgc ccataagata aataatggag aaccacttta tctaaataca
    26041 aaaggtaaag atttcttttt tataagaaaa tcaactaatg aagaaatttt aaatgaaata
    26101 ataggattgg ttaatgaaag attacctaaa ttttataaag ttgataaatt aaaagatata
    26161 caagttttat cttcaatgag aaaaggtgaa ttaggagtta ctaatctcaa tatagagtta
    26221 cagaagtatc ttaacaaaaa agaaaaattt aaagttgaag aaagtttttc taaaagatta
    26281 tttagagttg gcgataaggt aatgcaagta aaaaataatt atacaaaaaa atgggaaaca
    26341 gaagaccaaa aagaaagtgg agaaggtatc tataatggag atataggata tgtttatcac
    26401 atagataaag ataagaaaac tatttatgta ttatttgacc agactaaaat tgtatcatat
    26461 ctatatgatg aattagatga aattgaccat agtttttgta caacgataca taaaagtcag
    26521 ggaagtgaat ttccagttgt agtattgcca ataacttggg ctcctcctat gctacttagc
    26581 cgtaatttat tatatacagc agtaacaaga gcaaagaaat tagttgtatt agttggagat
    26641 gtgaagtatc ttgaatatat gataaaaaat aatagagtta atcaaaggta ttcaaattta
    26701 gggtataagc taaataaatt taagcaagaa gggttgttga tagaataaat atgaaaatat
    26761 gcaatgataa ttttattaag gattttaaaa atatgattaa taaatgtctg gattttatat
    26821 atcctgagaa tataagttgc ataatttgtg ataaatccat aaagaaaaca aatacttatt
    26881 caatatgtaa aagttgtttt aaagaaatga attttataca agatggttgc atgaagtgtg
    26941 gaaaaccaat aatacatcat tcaattgaaa aagagtttat tgaagagtgc agttattgtt
    27001 ttaacaaaga cttttacttt gataaatcaa tatcttgtat tgaatataat gatgtaacaa
    27061 aaaagatagt gttagggctg aagtataacc aaaaaacctt tatggctaag tatatagctc
    27121 aaataatgaa agaaaaatta tatttagaaa acataaaatt tgattatgta ctatttgttc
    27181 cacttcataa aaaaaggtta aataaaagag gttttaatca ggcgcaaaaa atagcattta
    27241 atttaagtaa aatagtaaat attccattat tggattgtat aagtagaaaa aaatatacaa
    27301 gaatgctata taaattaaat aaaaaagaac gaaaagaaga gttaaaaaat gtatttgttg
    27361 ttaaagaaaa tattaaatta ataaacaata aaaatatact tttaatagat gatatattta
    27421 ctactggtct aacaacaaat gaaatctcta aacttttaaa gttatccggt gctaataagg
    27481 tttttgtatt aactctactt acaaaagcaa atgataatta tattatggaa taatcttata
    27541 tattgacaat tttaatttaa aatattaaaa tgaataggtg atatttaggt ctgtggttga
    27601 aagtccaagc cagtcgcagg caaaaggatc cacgtaagtt aacactaaaa attgggttaa
    27661 tgatcatggt gcggcttaga agtaagacct accgataata aaatcgagag agagtagtag
    27721 tgcggcgaac ccaagcgaac cctccagtag gcgagtgtgg ggtcaaaaac caggtcagct
    27781 aaatatcata ttaaaagaga gctagcatac ctttatgtat agctcttttt tatatataat
    27841 aaattaaggt tgagtcataa agaggtgata tgtttgaata aaagacaaga aaatttatta
    27901 acaacattgc tattaaaaga agagtttata aatgttaatg aaattgccaa tgattttgag
    27961 tgttcagaaa ggacgataag aaatgattgc aaatatattg atgaatggct atctactttt
    28021 tgtaatgctt gtatcaaaag aaaacctaat attggaatta aatttagtgg agatggaaca
    28081 gataaaatac tggtaaatca gaagttgcga ggtgaagtta aaagagtaaa tagtgagctt
    28141 cataagcaag ttgagatatt aaatttacta ctttgtaata ataaaaaagt tactttaaat
    28201 gatttgtcta ataagttgta cataaataaa aatattgtca gagaagaaat aggtaaatta
    28261 tcagtggcat taaataatta taacctaaat atctcaacta aaaaaggtag tggtatatat
    28321 attgaagggg atgagaaaga cataagaata atgttagtat cattcttatt taaatacata
    28381 gataaataca gattaaacat agatgaaata gaatatttcc atatagtaga tataataatt
    28441 gtaaaaaaca taatgtttac tatagaagag aatatggata taagacttac agatatatca
    28501 ttcaagcaat tgatgctatt tttgcttata aatataatac gaataaggct aggaaattct
    28561 ttaaaagtat caaatactaa gaaagagctt aagctaaaaa tgcttatact agatatagaa
    28621 gatgaactaa aatctaattt atctatagta ttaaattatg aagaaaagct gtttatagaa
    28681 tctttaatat tgggtatgaa taaacaaata aatagcagta atattaagaa atctttatat
    28741 ctgaatgaag aattagcaaa ttatacaaga aaaattataa atttagtatc agaagaatca
    28801 ggaataaatt tcaataatga tatattactt tatgaacaat taatatgtca tctgaatgtt
    28861 acaatgcatc aaatgaaaag caatgtttac ttagaaaatc cacttttaga taacataaaa
    28921 actaaatttt gttttttatt tacagtaata tcaagttcaa tagaaattga attaaaagga
    28981 aaacaaataa cggaagatga aatcggttat cttacacttc actttcaaac ctctctagaa
    29041 agaaaataca gtaaaaggga atcaaataaa aaagcaagta ttgtatgtcc atttagtttt
    29101 ggagtaagta tgctattaaa agtaaagata gaaaagagat ttgacaacat aaaaattatt
    29161 gaaacattaa gagaggaaga tttaaaaaga gataacttca ataagacaat agattttata
    29221 attgcatttc aagagtatga gaatattcaa aaaccaattt ttataacaac accattattt
    29281 actgatgagg atgagaataa acttaaagag ttcacaaaca aaataaaaga aaaagatact
    29341 tcatataagc ttatgaacag attgatgatg tctgattatt taataagaga gttagaacat
    29401 gatgatattt atgaagctat aacatattta actaatttat tgattgaaaa acattatgca
    29461 gaaaaagagt atttacaatc tattataaca agagaaaagt catacccaac caatgttggg
    29521 aaaggaatat tattccctca tggagatatg aaatatataa aacaatctgt tttatgtttt
    29581 gcaaggttaa aaacaccaat aaaaattaga aatggaaaag atataaagat tatactttta
    29641 ctagcctata aaaaagatga tgatagaaaa gtatttagag aattatttaa agaaatatct
    29701 aatttaactg aggatgaaaa tatgctagat attctaagta aatgtgacat tgaaaaagta
    29761 aaagatattc ttatataaaa ttcatagaga cctatggata agcacaaaat tttccatctg
    29821 atggaaaaag ttgtgcatgt tttttgtttt ttataagata ttatatgttt ataaggtata
    29881 aataatctaa aaacagagaa gcaatttagg aggaaaaaat ggaagaaata gtcttaaaga
    29941 ttataattca cgctggaaat gcaaaatcta tgctttatga agcgcttgat tatgcgaagg
    30001 aaaacgattt taaaaaagcg gatgaattaa ttgaaaatgc aaatgaagaa atcttaaaag
    30061 cacataaagt acaaactgaa cttatacaaa aggaagctgg gggagataaa tcagatatat
    30121 ctattttatt aattcactct caagaccatt taatgacttg tatgagtgag agaaatctta
    30181 taaaagaaat gattatgtta agaaaagaaa ttcaaaaatt aaaatgaaaa atttaagggg
    30241 gatttaaaag aatgaaaaga aaagtatatt tattttgtag ctttggtatg tcaacaagtt
    30301 tacttgcaga gaaaatgcag aaggtggcag atgaacacaa tttaccaata gaagtagagg
    30361 catttccaat agcagaaatt gataaaatag ttgaagaaaa aaatccagat tgtatattat
    30421 taggaccaca agttaaatac atgctaaagg aattaaaacc aaagtttgag gctcaaggta
    30481 aacttataga tataataaat gaagttgatt atggaactat gaatggggaa aaagtactaa
    30541 agcttgctat aaagttaata aaatctaagc aagcatagga ttataaataa aaaacaatga
    30601 gagatgaggg tggatagatg aatagattgg aaagaatact tatgccattg gctgaaaaaa
    30661 taggtaaaaa taagttatta attgcaatta gagatggttt tttaatatca tcaccattat
    30721 taataatagg ttcattattt ttattagtat caaacttccc aataaaagga tggaatgaat
    30781 ttgtaggtca aatttttggt ccagattggg ctgtaaagtt acaacaacca actgtagcaa
    30841 catttgaagt aatgactcta cttgcagttt taggaattgg atattcttat gcaaagcaaa
    30901 tagatgtaga cccaatagca tcagcagcag ttgcaatagt tgcctttttt ataataacac
    30961 catttgtaat accatataca ccagagggaa cagaatcagt atacatggtg acaggtatac
    31021 cactaggttg gatgggttct aagggaatgt ttgtaggtat gataacagca ataacctctg
    31081 taaaattatt tgctgcagtt gtaaaaaaag gatggacatt gaaaatgcca gatggagtcc
    31141 ctccaactgt atcaaaatca tttgcagcat taataccaag tgcaatagtt atggtagttt
    31201 tctttttagt taagatagct tttgaagcta caccatatgg aagtgtacat gaatttatat
    31261 ttaagttttt acaaatacca ttattaaaat taggaaatac tttaagtgct acagcaattg
    31321 cttatgtatt cttacatcta ttctggttct ttggaataaa tggaagtagt gttgttggag
    31381 ctgtgtataa tccaatatta aaaattctat cagctgaaaa cttagctgct tttcaagctg
    31441 gtacaaaact accaaacata ataactgctc aatttcaaga tatgtttgca acatttggtg
    31501 gagcaggtag tacattatca ttaattatag ccatgttatt aatatgtaaa agtaaacgta
    31561 taaaatcaat aggaaaatta tcaattttac caggtatatt tggtataaat gaaccattaa
    31621 tatttggtct accaataatg cttaatccaa tactattgat accatttgca ctagttccaa
    31681 cagtaaatat aataatagct tatttctgta tgtcaacagg attagtgcca cttacaaatg
    31741 gagttcagct accatggaca actccaatta tattctctgg atttctaaca acgggatggc
    31801 aaggggcagt tttacaatta gtacttatta tactaggaat atttatgtat ataccattca
    31861 taaaaatgct agataaacaa tatttgaaag acgaaaaatc aaatgttgaa ggggaagatg
    31921 atgatatatc ttttgatgat ttagtattat aggaggaaga ttatgaagaa aatagtaatg
    31981 atattggatc aaatacaagc tggagcggga ggaaaagaga aaagtaatat acctcctgct
    32041 ggaaaatcaa gcccattagg accaggtgta atgatggaac catttttaaa tgaatctaaa
    32101 gtaatagcta cattattttg cggggatgaa ttttttataa ataatgaaga agaagtgact
    32161 agtaagatga tagctatggt aaaaaaatta aaccctgatg tagtaatctg tgggccaagc
    32221 tttaattatg aaaacttttc taagatgtca gcaatactgt ctaaaaatat aaacgataag
    32281 gcagatatac cagcttttgc agctatgtca gaggaaaata tagatgtgat aaatgaatat
    32341 aaaaatgaca tatgtatagt tagaactcca aaaaaaggtg gaattggtct taatgattcg
    32401 ttaaataaca tatgtaaatt agctaaagca atggcaaata aagaagatat aactttgatg
    32461 aaagaagaat tttgttatta atatgagtat taattattag caagtttgaa tattacacta
    32521 tttataataa gcatatatta ttaaaatcta tatagtttaa ggaggggaat tttagcatgt
    32581 ggggaatgat tgcgacatgg agaatggccc tagaaggaat aactgaggca tcagaacatt
    32641 tagaaaaagg catggaagca ggtgatgctg tagagcttgc tgtaagaaga gttgaagact
    32701 atccattcta taaatcagtt ggatatggtg gacttccaaa tgaaaattgt gaggtagaac
    32761 ttgatgctgc atttatggat ggtaacacat tagatattgg agcagttgct ggtataagag
    32821 attattctaa tcctgtcagt atagctagga agttaagtta tgagaaggta aataattttt
    32881 tagttggaat aggtgctgaa gagtacgctc ataaaaatgg atttgaaaga aaaaatatgt
    32941 tgactgatag agcaaagtta cattataaga aaagaaaaaa agagacttta gataagggat
    33001 taagtccata tgctggtcat gatactgttg gtatgatatc tttagataaa actggaaaaa
    33061 tgtgtgcagc tacatcaaca agtggattgt ttatgaagaa aagaggtaga ataggagatt
    33121 ctgcactgtc tggttcggga ttctatgttg atagtagtat aggaggagct acagcgactg
    33181 gtttgggaga agatttaatg aagggatgta tatcttatga gatagttaga cttatgaaag
    33241 aaggaaaaca tccacaagaa gcatgtgata ttgcagtaaa cgaacttgat aaacagctta
    33301 ttaaaagaag aggaaaagct ggtgatttgt cattagttgc aatgaataat aaaggtgaat
    33361 ggggagtagc tacaaatata gctgatttta ctttttcagt agtaactaaa gaagaatccc
    33421 ctactgtata tatttcaaat agagtagatg gaaagactat acataaggtt atatcaaatg
    33481 agtggatgga agcatatgag gctagaataa aagcaccaat agaagtaagt gagtaaagta
    33541 gtagttacat aattaaaata gagttttata ataaggagat ttttatgaat atcataagta
    33601 ataaaataga tgaattaaaa gaagatttat taagtgatat tatagatatt gtaaaaatac
    33661 ctagtgtcaa aggggagtca gaaaatggct tcccttttgg tgaaaaagta ggggaggcac
    33721 ttaataaagc attagaaata tcagaaaaat tgggatttaa gattagaaat ttgaataatt
    33781 atattggtta tgcagagcat ggagatagcg aggattatgt ttgtgtaatt ggacatgtag
    33841 atgttgtaca tgaaggagac ggttggaaat atcagcctta taagggagaa gaaatcaatg
    33901 gaagaattta tggaagagga gtactagata ataaaggtcc tataatatct gctttatatg
    33961 gattatatgc tattaaagaa ttaaatttaa aattagataa aagagttaga ataatatttg
    34021 gtacaaatga agaaagtgga tttgaagata taccatatta tttagaaaaa gaaaaagcac
    34081 ctatcatggg gtttacacca gattgtaagt atcctgttgt atatggtgaa aaaggcatgg
    34141 caaagattag aataaaaagt aaaataaatt atgaagaaga tgtattatta ggttttatag
    34201 aaaatgtgtc tgaaaatgtg cttgttacat ataaagagct aaatatagaa aatagtgata
    34261 ctatattgga tataaaggta aaatacgatt ttagttataa attaaaagat gtattagatg
    34321 aaataaaatt tagttttcca aatagtatcg atatagaggt aatttctaat tttaatcctg
    34381 tatattttga taaagagagc aatcttgtta aaaagcttca gctggcttat gaaagggtta
    34441 catcactaga tggaactcca gtaacaacta atggaggtac atatgcaaaa gtaatgccaa
    34501 atatagttcc gtttggccct tcattcccag gacaaaaagg aatagctcat aatcctgatg
    34561 aatatatgga tatagaagat ataatattaa atgcaaagat atttgcaaat gcaatatatg
    34621 aattagcaaa ggagtagtta tgttagagat aataggaatg tcagtagaag acgctaaaat
    34681 tatagaagat tgtggtgcag atagaataga gttagttagt gctttaactg aaggtggatt
    34741 gacaccaagt tttggtctta tagaaagggt tgttaacagt gtaaagatac ctgtgaacgt
    34801 aatgataagg cctcatgcga aaagttttgt atacagtaaa gaagatataa atataatgca
    34861 aaaagatgta agtgttgtta aagagattgg tgctaatgga gttgtatttg gtgtattgga
    34921 taaaaacaac aatatagatg agaaaaatct aaatgtttta ttgaaatgtt gtgataatct
    34981 tgatgttaca tttcatagag ctatagatga atcaaataca atagatagtg ttaaaacttt
    35041 gaaggattat gataaaatta taaatatatt aacatctggg ggaaaaggaa gtatagttga
    35101 taacatacaa ataataaaga atatgatgct tagttctaat cacataaaaa ttcttttagg
    35161 tggaggactt aattttaata atatagaaaa gataaaggaa ttaactaagg caagtaattt
    35221 tcattttggt acagctatta gaatgaataa cagtcctttt gaagatatag atagacaaaa
    35281 gcttagacag cttgtaaata taatttcaag atagtatata aatataaaat acttagttta
    35341 aataaagaga gtaagttaat tataatttgg gtatatgaat gttaataggt attacatatg
    35401 aaattattgt tgagtatgct ttacaacttt taagtagttt taaatataaa taatgaaagc
    35461 aaagatatag taacgaggtt ttagagggtt tatatttatt aaaaaattat aaaggtatac
    35521 tggcatataa cacatataat ttcctaaaat taccatctta tgacataaat tcacatatta
    35581 ataaacaatt aatggagatt tttgtggata gaaataggag caaaaatagc tttaaataaa
    35641 caaaaacagg agttattaac agttttatcc acattatcca caggtgtttg taataatatt
    35701 aatccacata agtataaatt taactaaaaa tgataaataa ttctatcaat tgaatagaaa
    35761 aaatcataaa agtaaataat aaaaagagga ttatgagagt tcgcgtagaa tatattatta
    35821 aagtataaat tttcttatac tggcataatt gaagggagat gtacttatga acataattat
    35881 atctggaaaa caaatcgaat taactgatgc aataaaaaat aaaatcgaaa gtaaactaag
    35941 taagttagat aattacattc atccagacac tgatgtaaaa gttacagtaa gtgcgagaaa
    36001 agcaagacaa aaaatagaag taacaatagc tactgtaaat ggacctataa ttagagcaga
    36061 agatatgcag gaaaatttat acacagctat agatgttgta tatgataaat taagtaaaca
    36121 attgaaaaaa tataaaaaga gactacaaga taagcataaa gacaacaaga gtataagatt
    36181 ccaagacgca gagataaatc tagctgatga acaagaggat tatggggatg aaaatcaaga
    36241 attagtaatt caaagacgta agaaatttag tgttaagcca atgagtgaag aagaagctgt
    36301 attacagatg gaactaatag gacatgattt ttatatgttc aagaacatag attcagatga
    36361 aatagcagta gtttataagc gtaataatgg tggatatggt ataatagaac atgaataaag
    36421 caatttagat ttaatcatat tagctatcga taaataaatt atcgatagct ttttaaatta
    36481 atattaaaag tatagttttt atggtaaaat gaataatagt acaataaaga acgaggagag
    36541 atgtaaaata tgagctttat ggataattta ttcaacatgg cagataaaaa agaattaaaa
    36601 aagttcaata agactgttga tataatagat tcattagaac ctaaatttga atctatggca
    36661 gactcggaac ttaaaaatat gacaaatata tttaaagaaa gattagcaaa tggtgaaagt
    36721 atagatgata tacttccaga agcttttgca gtagttagag aagtttctaa gagagtgtta
    36781 ggacttagac actacagagt tcaaatgatt ggaggtatag tactacatca aggaagaata
    36841 gcagaaatga aaacaggtga aggtaaaact ttggttgcta ctgctcctgt ttatttgaat
    36901 gcgcttactg gaaaaggtgt acatgttgta acagtaaatg attaccttgc aaaacgtgat
    36961 agagaccaaa tggcaaaaat ctatgagttt ttaggaatga gtgtaggcgt tattatacat
    37021 ggtcaaaacc caaaagtcag aaaagaacaa tatgattgtg atataactta tggtacaaat
    37081 aatgagtatg gatttgacta tttaaaggac aatatggtaa tacacaaaga gcaaagagtt
    37141 caaagaggat taaattatgc tatagtggat gaggttgact ctatactaat agatgaggct
    37201 agaacaccac ttatcatatc tggacctgga gacaaatcaa ctcacttata ttcggatgca
    37261 aacacatttg ttttaacatt aaaaccagat gattatgaat tagaagaaaa agataaggct
    37321 gtatctctaa cagcatcggg tatacaaaaa gcagaagtat attttaatgt tgataatata
    37381 acagatatat ctcatacaga attataccat catataaatc aagctttaag agcacatgta
    37441 ataatgaaga aagatgttga ttatgttgct aaagatggag aaatagtaat agtagatgag
    37501 ttcacaggta gacttatgtt tggtagaaga tattcagaag gtttacatca agcaatagaa
    37561 gctaaagaag gtcttaaaat acaaagagag tctaaaacac tagctactgt aacattccaa
    37621 aattacttta gaatgtacaa aaaactttct ggtatgactg gtacagcaaa aacagaagaa
    37681 gaagagttta aagcaatcta caaaatggat gttttccaag tacctactaa taagcttatg
    37741 ataagggaag acttgccaga ttgtgtatac aaaagtgaaa taggtaaatt caatgctgta
    37801 gcccaagaaa taattgaaag gcataaggtc aatcaaccaa tacttgtagg tacagtatca
    37861 atagaaaaat cagaattatt gtcacaaata ttaaagaaaa agggcataaa acatgaagta
    37921 ttaaatgcta agcatcatga taaagaggca gaaataatag cacaggctgg tagacttgga
    37981 gctgttacaa tagctactaa tatggctggt cgtggtacag atatagttct aggtggaaat
    38041 ccagactttt taactaagag agaaatgaga agaaatggat ttaaagaaga aatagtaaat
    38101 agagtagata ctccaataga aggtatacct gtaaaaggta atgaaatttt atttgaagct
    38161 agagaagagt atgaaaaact atttgaaaag tttaagcaac aaacgcaaga agaacaaaaa
    38221 caagttgtag aagcaggtgg acttgctata attggtacag aaagacacga atctcgaaga
    38281 atagataacc agttgagagg tcgtgctgga cgtcaaggtg acccaggtag ttcaagattc
    38341 tatataggtc ttgatgatga ccttatgaga ttatttggta gtgatagaat atctggtatt
    38401 gtagataaga taggtcttga agaagacatg cctatagaac atagaatatt atctaagtct
    38461 attgaaggag ctcaaaagaa agtcgaaggt aaaaactttg gaataagaaa gcatgtactt
    38521 caatatgatg atgttatgaa taaacaaaga gaaataatat acgcagagag aaaacgtgta
    38581 ttagaaggcg aagatttaca agaacaaata caatcaatga ctcattctat aatagaagaa
    38641 gcagttactc tttatacaca agataaagga tttgatgaag aaggattcaa agaacatatg
    38701 tataatctgt tcttgccaaa aggtagcata gaaataccag aaatagaaaa acttaatcca
    38761 gttgaaataa cagaaaaagt ttatgaaata gctatgaaga tatatacttc aaaagaagaa
    38821 caagttggct atgagagaat gagagaagtt gagagagtaa tcttacttca agctgttgat
    38881 aaccattgga tagaccatat agatgctatg gaccaattac gccaaggtat cggtcttcgt
    38941 gctgtaggtc agcaagaccc agttattgct tataaaatgg aaggttttga tatgtttgat
    39001 gaaatgaata aacatatcaa agaagatact gtaagatatt tatttaatat aacaatagaa
    39061 actccagtgg aaagaaaagc agttgtagat gttgaaaatc tatcttctcc atcagatgga
    39121 acacttccaa taagtaaaac tgttaaaaaa gatgaaaaag ttggaagaaa tgacttatgt
    39181 ccttgtggaa gtggtaaaaa atataaaaac tgttgtggaa gataatcttg gaggattaaa
    39241 tgttaaagtt acaagaatat agacatagta tggagcagat ggcttcaaat ttagaagaat
    39301 tgagggtttc tctttgacat agcttcattg atgaaaaata tacaaattaa tgaagaaaag
    39361 atgaataaac aagacttttg gaatgataat gaagtcgctc aaagagtact tcaagaaaat
    39421 aagtccttaa aagagacatt agaagaatat gaaagcttaa aaagcttatt agaagatata
    39481 gaagtattaa ttgaaatagg tctagaagaa gaggatgatt ctgtagaaag agatatagaa
    39541 aagtccatag aatcaatgga agaaaaatta tccgaaatga aaataaagac tcttctaaat
    39601 ggagagtatg ataaaaataa tgctatatta tctataaatg cgggtactgg tggattagat
    39661 gctcaagatt gggctcaaat gcttttgaga atgtatataa gatggtcaga aagtaagggt
    39721 tataaagtta agctcttaga tataatatca gaccctgaag cagggataaa gacagctaca
    39781 attcttgtag aagggacaaa tgcttatggg tatttaaaga gtgaaaaagg agttcatagg
    39841 ttagtaagaa tatctccatt tgacccatca ggaaaaagac atacttcatt tgcatctata
    39901 gatgtaacac cagagttaga tgaaaatata gaagtagaga ttaatccatc agatttaaag
    39961 atagacacgt atagagcttc tggagctgga ggacaacatg taaatacgac tgattcagca
    40021 gttagaataa cacatattcc tacaggtgta gtagttcagt gccaaaatga aaggtctcag
    40081 catctaaata aggatagagc tatgagactt ttaatggcaa agttgataga attaaaagag
    40141 ttagaacaaa aggaaaaaat agaagatata caaggcaaat actcacaaat aacttggggt
    40201 agtcaaatta ggtcatatgt ttttcaacca tataaattgg ttaaagacca tagaacaaat
    40261 gctgagtttg gaaatgtaga tagtgtaatg aatgggaata tagacttgtt tattaatgaa
    40321 tacttaaaaa tgaataaaat agtttaataa atatgcattg taattaagat atatgtataa
    40381 gaaggttagt gcttaatatg cacttacagc acttaggctg aggacgataa ccctcagcct
    40441 tcgttctgtt ttgttatact tatgaaaaaa ctaacattag gagtgaataa attggatata
    40501 aatcaaatct taaaaaaaga gtttaatctt agagatgaac aaataaataa tacattaaaa
    40561 cttattgatg aagggaatac aataccattt atagctagat acagaaaaga aatgactggt
    40621 gaaatgagtg atgttacact aagagaattt tatgaaaaat tgatgtattt gagaaatctt
    40681 caaagtagaa aagatgatgt agttaggcta atagatgaac aaggtaaatt aacagatgaa
    40741 ataacacaaa atatagaaaa agcaaaaaca ttgcaagaag tagaagatat atatgctcca
    40801 tataaacaaa agaaaagaac tagagcaaca atagcaaaag aaaaaggatt agaaaactta
    40861 gcattgtcaa tactagagaa taatttagat aatattgaaa tagaggcaga gaattatctt
    40921 gatgaagaga aagaagttct ttctattgaa gatgctctaa aaggtgctag agatataatt
    40981 gcagaattag tatcagatga tgctaagatt agaaagtata taagagaatt agcattaaga
    41041 gaaggtatga tagttagtaa aagtgccact gatgagaaat cggtttatga tatgtattat
    41101 gattatagtg aagcagtaaa aagtatggct ccacatagag ttttggcaat aaacagaggt
    41161 gaaaaagaaa atttcttaaa ggttaagtta gaaataaata atgataaggt tttaaattac
    41221 ataataaatg aatatgtaaa tgataaaaat ttcaaaaata aagaagaaat tgtaaattca
    41281 atagaagatt cctataaaag attaattttt ccatcaatag aaagggaaat aagaaatcat
    41341 ttaacagaaa tagctcaaga aagagctata agtgtgtttg gaaagaatgt taaaagttta
    41401 ttacttcaac caccagttaa agacaaagta gttatgggat ttgaccctgc atttagaact
    41461 ggatgtaaaa tagctgtagt agataaaaat ggtaaactac tagactatac aacagtatat
    41521 ccaacagacc ctcaaaatga tgtagaagga gcaaaaaaag ttttaaaagg attgattgaa
    41581 aaatacgata tagatataat ttcaattgga aatggtactg catctagaga atcagaaact
    41641 tttgtatcag aaatgataaa agagatagat agagaagtgc agtatgtgat agttagtgaa
    41701 gccggagcat ctgtttattc agcatctgaa cttgcaaatg aagaacatcc agatataaat
    41761 gtatcaataa gaggagctat atctatagct agaagattac aagacccatt ggcagagctt
    41821 gtaaaaatag accctaaaag tattggtgtg ggtcaatatc agcatgattt aaataaaaag
    41881 agattagaag aagtactaga tggagttgtt gaagattctg taaacagtgt tggagtagat
    41941 ttaaatacag catcatactc tctactagag catattgcag gaataagtaa agctattgca
    42001 aaaaatataa tagcatatag agaagaaaat ggagatttta catcaagagc acaattgaaa
    42061 aaagtaaaaa gactaggacc tcaagcattt actcaatgtg ctggatttat gagaatctta
    42121 gagggtaaaa atccattaga taatacaggt gtgcatcctg aaagttatga tatatgtaaa
    42181 aaaatgattg agataatcgg gtattcttta gatgatgtaa agaataaaaa tatagatgaa
    42241 atagatgaaa aaataaaaga aattggcttg aaagaattaa gtgaaaaact agaagtaggt
    42301 caagttacat taaaagatat catagctgaa atcaagaagc caggaagaga ccctagagaa
    42361 gaaggtataa aacctatact tagaactgat gtcttaaaaa ttgaagatat acaagagggt
    42421 atgattttaa aaggtacaat aagaaatgtt gtagattttg gtgcatttgt agatattgga
    42481 ataaaaaatg acggattagt tcataaatca gaaatgagta atagttttgt aaaagaccct
    42541 atgagtattg ttacagtagg tgatatagta gatgtaaaag tcattggaat tgacttaaac
    42601 aaaaaaagag ttgccttatc aatgaaaaaa tagataagtt tatgtatggt tatagtactt
    42661 aaattctatg tttgtaaatg aagttaccag agtgtataaa tgttaaaaac ttgtaaaggt
    42721 atatagtaag aaaatacatt aaaataagaa cgatagtctt gaaaatcagg aggaaaatga
    42781 atgattttta taaaaaatgg taaaataaat accataacaa atgggataat tcatggagat
    42841 atacttatag aggaaggaaa aataatagaa atcggagaag atttgatagc acctttagat
    42901 gtagaggtca tagatgcaag taataaactc gtgtttcctg gatttataga tgctcataca
    42961 catttaggtt tatgggaaga tggtataggg tttgaaggag cagacggaaa tgaagagact
    43021 gacccaataa caccacaatt aaatcctgta gatggaatta atccaatgga taggactttt
    43081 aaagaagcat ttgaaggtgg aataacttct gtttgtacaa ctcctggaag tgcaaatgtt
    43141 atgggtggtc aatgtatagc cataaaaaca tatggaaaaa gaattgataa aatggtaata
    43201 aaaaatccag ttgcgtctaa aattgctttt ggggaaaatc caaagagctg ttacggtcag
    43261 gatgataaat ctccccaaac tagaatggca atagctgcct tacttagaga aaacctaaaa
    43321 aaagcagaag aatatttgga agatattgat atgtatgaga gtcatgatga tgaagactgt
    43381 gaaaaacctg aatatgatat aaaaatggaa agtttaatac ctgttttaag aagagaaatt
    43441 ccttttaagg cacatgctca tagagcagat gatatgttca cagcaataag aattgcaaaa
    43501 gaatttaatt taaagcttac attagaccat tgtacagaag gtcatcttat tgcagatgaa
    43561 ttagtggaag aagggtttcc tgtaatagta ggtccatctt tgtcagaaag gtctaaattt
    43621 gagcttagaa atttgacatt taatacagca ggaatacttt caaatgcagg tcttgatgta
    43681 tgtataatga cagaccatcc agtaatacca gttcaatatc ttccaatatg tgcaggtatt
    43741 gcagtcaaac atggtatgaa agaagaaaaa gcaatagaat caattacgat aaatccagct
    43801 aagactttag gaatagaaga tagagtaggc tctatagaag ttggtaaaga tgcagaccta
    43861 gtaatttggg ataattctcc actagagatt caaagtaatg taatttacac tataataaat
    43921 ggcaaagtag tatatgagaa aaaataactt gacaattatt aaaaaattaa ctagtataag
    43981 agtgtaagga aaattaaaaa atcaaagaag atcttcgggg cagggcgaaa ttccctaccg
    44041 gcggtatagc ccgcgaacta cttaagtggt tgatttggtg agattccaaa gccgacagta
    44101 aagtctggat gagagaagat atttatggaa gataaataag tttattttag tttgtttaaa
    44161 ctatatccat aaaaactcga agatagggtc ttcgagtttt ttgtttttcc taaaaaatat
    44221 aaacatattg attaggggga aataattatg caaaacacag ccaaaagagg caatatgatt
    44281 tcaacaagaa ctttagtagt aatgtcaatt ttatctgcaa tatcttattt attaatgttt
    44341 attcaagcac caataccagg tatatttcca gatttcttaa aaattgactt atcagatatt
    44401 ccagcaatat ttggaggaat gtctctagga ccattagttg gatttggaat agttgtagta
    44461 aaaaatgtgt tacaagcaat aacagcaaca acaactggag gaataggaga atttgcaaat
    44521 atattaattg gtggttctta tgtaatgata ctttgttatt catataagag aagtggagat
    44581 ttaaaaggtg tattgattgg ttttgtatta ggaacaatat ctatgactat aattggttca
    44641 ttagtaaatt attttgtaat gttgccactt tatggtcaac ttatgggact agatgctata
    44701 ataggtttag gttcagctat aaatcctcaa gttcatgatt tattcacttt tgtaatttgg
    44761 atgatagctc catttaatgt gctgaaggct gttataatat ctttagtaac attgccactt
    44821 tataaaaaaa tgggaaatat aataaaaaaa taatttagac aagaaaatat aaaattaaat
    44881 gtattgaata gccatagttt atttataact tcagtcctat attgtgattg atatattaaa
    44941 tatattatgg ctttattaat ttatcaaaaa atgtatataa aataagaaat atttagacaa
    45001 atttaaattt taaaataaag gaagaattaa aacgattaac tattaaaata tgaaaaaggt
    45061 atctgcaata tacagagcga atttataata agcaaaaaat aaagttatta ttaaaaaaat
    45121 ataaagatta gtaatcaaat ttttaataat aactaattta ataatgatgg gagtgtatat
    45181 tcatgaactt atctaaaaag ataaaaaaat tatttttaga tgataaaggg tattatttta
    45241 atagtaattg gaaagatatt catattggta tttatgatac aaaactagga gattctttaa
    45301 agtatatcac taatgaatat attgaaaatc tggaaagggt aaaatatgat tatcgtgaat
    45361 taaaaaatat agaaaatcaa actgatggta tgtgtatttt agcaataagg cagaattaca
    45421 aggcattaga gtatgtgaaa agtcaaactg aagaattatg tttagaagca ataaagtata
    45481 attataaagc acttgaatat gtaaaagagc aaacagaata tatatgtctt gaagctataa
    45541 aaaaggattg taatgcactc aagtatgtac gaaataaaac agaagggctt attataaaag
    45601 taatacgtca ttctaccaat atagatgttg taagtatact aaaggcttta gagactcaaa
    45661 caagaagaat atgtttagaa gcaattaaaa aagatggcag gtgtcttgca tacgttagag
    45721 aacagagtga agaattatgt atagaggcca ttaaacaaaa ttataaagca ttaaaatatg
    45781 tagaaaatca aacggaaaaa atgtgtatag aagctgttaa acaaaatggt atggcattac
    45841 aatatgtaaa taaacaaacg gataaaatat gtatagaagc tgtcaaacaa gatggaagaa
    45901 gtctacaatt tgtcgataat aagacagaag aaatatgtat aaatgctata agatatttaa
    45961 ataaaaaata taatattaaa gatgtgctgt gttacgtaga taattataca gaagatatgt
    46021 gtatagagat tgtaagacaa aatggaaaaa tgcttatgta tataaaaaat caaacagaaa
    46081 aaatatgtat tgaagcagta aaagagaatt ataagtctct taagtatgta aaagagcaat
    46141 ctgagagaat atgtaaagaa gcattgaaac aaaattataa agcaaaagag tatgtaaaaa
    46201 ttgccattga tgattgtata taaggtgtat ctacaggcat caataatgaa agataaaaaa
    46261 agataaagac aagtacttta taataatctg ggcttatact ataattaatt aagcagtgat
    46321 ataaattcac atgacgatta tatcaaaatg gagatgaatt aatggcaaaa atatatttag
    46381 aaaatgaaaa taaaactaga gaaataggat ataaattagg taaactttta aaagaaggta
    46441 gtgttatctg tttagtagga gatttaggag ctggcaaaac tacaatgaca caaagtttgg
    46501 cagattcatt agggataaaa gattatataa caagtcctac ttttactata ataaatgaat
    46561 atgaaggaaa aatacctttg tatcattttg atgtttatag aataggcagt agtgatgaaa
    46621 tgtatgatat tggttatgat gaatatgtaa attcaaatgg aatctgtata atagaatggg
    46681 ctaatctaat agaagacata cttccaaaag aatatttgaa tatagaattg agatataaag
    46741 atgaaggaag agaaatgata ttaactccaa aaggagagtt ttataaagaa atagttgagg
    46801 agttgattaa ataatgaaaa tactaggtat ggatacatct tctatggcag caagcgtagc
    46861 agttgttgaa gatgataact taatatgtga atttacagcg aacaacaaaa aaactcattc
    46921 gcaaaagctt atgccaatga tagaaaatat gttgagcatg agtgatttaa gtataaaaga
    46981 tatggattta ttagctgtat gtataggtcc aggctcgttt actggactta gaataggtat
    47041 ggccacagta aaagctatgg ctcatgtaaa taatatacca ataatagcag taaattcttt
    47101 agaatctcta gcaaataaca tgaatttttg tgatagaaag atatgttgta tattagatgc
    47161 tcagaaaaat caagtttatt cagctaaata caagtttgaa aatggagaga tgatagaatt
    47221 agatggtgtt gatgttatag agtttgatgc tttagtagag gaaattgtat caactaatga
    47281 agaatttata atggttggag aagctgtata caaatataaa gataagctag agaatataga
    47341 aaatataaag ataccttcac cagctaataa tgtatctaaa gcaggaagtt tatgctcttt
    47401 agcattaaat aaatataata aaaatataga tgtacatact tgttatacaa taaatcctat
    47461 gtatatcaga aaatctcaag ctgaagtaca atatgatgaa aaaatgaaga ggctaaataa
    47521 tggaagataa tataaattta atagtaaatg atataaaaat agaagaaatg accattgaag
    47581 atatagatga agtttttgaa gtagaaaaaa attgttttga agattattgg tcaaaagagt
    47641 cttttagaaa agagttatct aatgaagtag caaggtatat agtagctaag ttagatggaa
    47701 aaattgttgg atatgtggga atttggctta tacttgatga aggacatata aataatgttg
    47761 cggttcatag tgactataga gggaaaaaaa taggggataa attgataaaa ggcatagttg
    47821 atttatgtaa agataataat attgcatcta tgacattaga agttagagca tcaaataaaa
    47881 tagcacaaaa tttatataga aaatatggat ttaaaatggg tggaataaga aaagaatact
    47941 acagtgataa taaagaagat gcaattataa tgtggaacca attaaaagag gtgtagagtt
    48001 tatgagtgat ataataacat tagctataga gagtagttgt gacgaaacag ccgcatcagt
    48061 tttaaaaaat ggtagagaag tactttcaaa cataatctct actcaaatcg agacacataa
    48121 aaaatttggt ggtgtagttc cagaagtggc ttcaagaaaa catgtggaaa atattgatat
    48181 agttgttcaa gaagctttag acaaagcaaa tatggatttt aatgatatag accatatagc
    48241 agttacatat ggacctggac tagtaggtgc tttactggtt ggtctatctt atgctaaagc
    48301 acttgcctat actttgaata ttccacttgt aggagtaaat catatagaag ggcatttaag
    48361 tgcaaactat atagagcata aggatttgaa acctcctttt ataacattaa tagtatctgg
    48421 aggtcatact cacttggttg aagtaaaaga ctatggaaag tatgagattt taggaaaaac
    48481 aagagatgat gcatctggag aagcctttga taagatttca agagcaatga atttaggcta
    48541 tccaggaggt cctattattg ataatctagc ccaaaaggga aataagcatg ctatagaatt
    48601 tccaagagcc tatttagaag aagatagtta tgattttagt tttagtggat taaaatcttc
    48661 tgtattaaat tatctaaatg gaaagagaat gaagaatgaa gaaatagtag ttgaagatgt
    48721 agcagcatct ttccaagagg ctgtagtaga ggttttatct actaaagcac taaaagcagt
    48781 aaaagacaaa ggatacaata tcataactct ttctggtggg gttgcttcta attcggggct
    48841 tagagctaaa ataacagagc ttgctaaaga cagtggtatt actgttaagt atcctcctct
    48901 aattttatgc acagataatg cagctatgat agggtgtgca ggatattata attttataaa
    48961 cggtaaaacc catgatatga gtttaaatgc agttccaaat ttaaagataa atcagtagag
    49021 taagataaat ttgtaaatat aaaagtattg tttcaaaaaa gtaagtagaa gtaaaattaa
    49081 atacaataaa aattaatata gtgtatatta aaacttgaag taaaactatt tataatcttt
    49141 atgtcccaat gaattgcaac acattttagg atataaaggt tgtctttggc ttagatttgc
    49201 ttcaagttta attttttctg tagaaagatt attttaaaaa gtgggtaata tacccttttt
    49261 tttcattctt aaaaagtttt atactaatta tagaaagatt aaggagggga agaaatgagt
    49321 caaagtaaag aagacaaaat aagaagtatt ttggaagcaa aaaatattaa atcaaatttt
    49381 caaaataaag aaaatttaaa tgaatttaat gaaaaaaaag caagtaaaag agcagaagac
    49441 ttattagatg tatattataa tacattatct actgctgata tggaatttcc atattggtat
    49501 aatagagaat atagaaaatc agatggtgat ataccagtag ttagaagagc taaagctctt
    49561 aaagctgctt tttcacatat gacaccaaat ataatccctg gtgaaaaaat agtaatgcaa
    49621 aagacacacc attatagagg ctcttttcca atgccatggg taagtgaaag cttctttgtt
    49681 gctcaaggag aacaaatgag agaagaggca aagaaattgg ccagtaacac agctgatgag
    49741 cttacaaaat ttgggtctgg cggaggaaat gttactgaaa gttttggaaa tgtcgtttca
    49801 atagctggta aattcggaat gagaaaagaa gaagtacctg tacttgtaaa aatggcaaaa
    49861 gaatgggttg gaaagtctgt tgaagattta ggttttcact atgaaaaaat gatgccagat
    49921 tatgatttaa aagaaaatct aatgagcacg cttatatgca tgtttgattc agggtataca
    49981 cttcctcaag gtagagaagt tataaattat ttttatcctt taaattatgg attagatgga
    50041 attatagaaa tggcaaaaga atgtaaaaag tcagttgcag gaaatgcatc tggagatggg
    50101 cttattggta tggaccgtct atatttctat gaggctgtta ttcaagttat tgaaggatta
    50161 caaacttgga ttttaaatta tgcaaaacat gcaaaatatt tagaaagtat agagacagat
    50221 ttagaagcta aaaaagaata ttcagattta gtggaaatat tagaacatat tgcacataaa
    50281 caacctcgta catttaggga agctcttcag ttgacttata caattcatat agcatcagta
    50341 aatgaggatg ctatatctgg tatgtctata ggtcgtttcg gtcaaatttt atatccttgg
    50401 tatgaacaag atatagaaaa aggattaatt acaaaagaag aggttatcga attattagaa
    50461 ctttatagaa taaaaattac ttgtattgac tgttttgctt cagcgggcgt aaatggagga
    50521 gtactatcag gaaatacgtt taacacttta tctataggtg gattaagaga agatggttct
    50581 acaggagcta atgagctaga agaattattg ttagaagcaa gtatgagatg tagaactcct
    50641 caacctagtt taactatgtt atatgatgaa aagcttccag aagatttctt aatgaaagct
    50701 gctgaatgta caaagcttgg ttctggttat ccagcatggg taaacaattc aaatggaaca
    50761 acatttatga tgaaacaatt tgctgatgaa ggtatgactg tagaggaagc aagagcattt
    50821 gcgttaggtg gatgtttgga aacgtctcca gggtgctgga aacagttaac tttaaatggg
    50881 aagacatact ctattgcagg tggagcaggt caatctgctg gttctggagt tcactttata
    50941 gctaatccta aaatcttaga acttgtactt atgaatggta aagactatcg tatgaatata
    51001 caagtgtttg agcctcataa taagccatta gatacttatg aagaagtcat agaagtattt
    51061 aaagattatt ataaacaagc aataaatgtt ttagaaagag caaataatat tgagttagat
    51121 atatggagaa aatttgatac ttctataata aattcactat taaagccaga ttgtctagat
    51181 aaaggtcaac atataggaaa tatgggatat cgttataatg caacattaaa cgtagaaact
    51241 tgtggtactg ttactatggt caattcattt gcagcactta agaaacttgt atatgatgac
    51301 aaagcattta cgatagagga aatgaaggat gccatattaa ataattttgg ctttaaagat
    51361 gcattagaag taggaaatta ttctatggca gaccaagtaa aagtagataa gactgggaag
    51421 tatgatgcta tttataaggc gtgtcttgat gcacctaaat atggaaataa tgatttgtat
    51481 gcagacaata ttcttaaaaa ctatgaggta tggttatcaa aagtatgtga agaagcacaa
    51541 tctttatatg ctaagaagat gtatccttgc caaatatctg tttctacaca tggaccacaa
    51601 ggagctgcta ctttggctac tccagatggt agattaagtg gaacaacata ttcagacggt
    51661 tcagtttctg catatgcagg aacagataaa aatggagtat atgcattatt tgaatctgca
    51721 actatttggg accaagcggt agttcaaaat tctcagatga atttaaaact tcatccaaca
    51781 actataaaag gacaacaagg aactaaaaaa ttattagatt taacaagaag ttatttaaga
    51841 aaaggcgggt tccatattca atataatgtt gtagattcag aaacattaaa agatgcacaa
    51901 aaaaatcctg acaattatcg tcaattaatg gtacgtgttg ctgggtttac tcaatattgg
    51961 tgtgaattag gtaaaccaat acaagatgaa gtaattgcta gaacagagta tgaaggggtg
    52021 taaaatatga gaaagcatag tgattgtatg aatttttgtg cagtagatgc aaccaaagga
    52081 atttgtagat tgtcaaaaca aatgattaat ttagatgatg aagcatgtcc agagataaaa
    52141 gtaatgccaa aatgtaaaaa ttgtaaaaat tttgttgaag ctaatgatga aggtataggc
    52201 aagtgtgttg gtctagaaaa ggaagactgg gtatattcaa cattgaatgc aattacttgt
    52261 gaaggacatg tgtttaatga gtagtcaaaa gaaattagaa ggtatgattt ttgatgtaca
    52321 aagcttttca gttcatgatg gtccaggttg tagaacaact gtatttttaa atggatgtcc
    52381 actgagttgt aaatggtgtg caaatccaga aagttggact gtaagaccac atatgatgtt
    52441 tagtgaatta tcttgtcaat atgaaaatgg atgtactgtg tgtcatggta agtgtaaaaa
    52501 tggtgcattg agctttaatc ttgataataa gccagttata gattggaaca tctgtaagga
    52561 ctgtgagagt tttgaatgcg tcaactcatg ttattataat gcgtttaaat tatgtgcaaa
    52621 agcttatact gtagatgaac ttgtgcaggt aattaaacgt gattctaaca attggagaag
    52681 taatggagga gtaacattta gtggaggtga gccactactt cagcatgaat ttttacatga
    52741 agtattatta aagtgtcatg aggtaaatat acacactgcc attgaaacga gtgcatgtgt
    52801 atcaagtgaa gtttttaata aaatatttga agatattgat tttgcattta ttgatataaa
    52861 acatatggat agagaaaagc acaaagaaca aacaggtgtg tataatgatt taatactaaa
    52921 aaatatatca aaccttgcaa attctgattg gaatgggaga ttagtactta gagtaccagt
    52981 tatctctggg tttaatgata gtgttaaaaa tataagtgat attatatctt ttatgcacaa
    53041 aaataattta gtagagatta atctattacc atttcacaga ctaggtgaat caaagtgggt
    53101 tcaattaggt aaagaatatg agtattctga taagggtgat gttgatgaag gtcatcttga
    53161 agaattacaa gatatatttt tggataatgg tatagcttgt tatgttggtc atgagacagc
    53221 tttctaaaat caaatacaag ttttaattaa aaaaggatgt tgtactaaaa gctagagtca
    53281 catccttttt tatgaggttt ttatgtataa agagttataa tatattttac taatttaaga
    53341 taaaaataat aattttttat aggtggaatc tttgcttgat atagaaatta ataataagat
    53401 tattccactt gttccctcta aaaaggatgt gttttccatt gtttctaaat tactaaatgt
    53461 tttaaagctg tatcttaatg ataaatcaaa caattgaaat atttcatcta aagttttttc
    53521 aaggttgtat agataaacat tatcatttgt ttttttgtac actgatgtca ttatagacaa
    53581 aatttaataa ctatccttta tattcttttg taaatagaaa tggaacataa aaaattaaag
    53641 aaaccataga tactattaat atgtcagaat aagtaataat tgactcttca acatttgtta
    53701 taagaaaagc gctattattt aaaatatgaa ttatagcaca aaaccagaca tttttagttt
    53761 tcatataaag atatcctaaa aatattgcaa ttccaactat atgtattgaa cgtaatatta
    53821 atcctaatat tggtgtttca ggtgtatata atgtaaatat tagtggtaag tgccacaaac
    53881 tccaacacat acctaatatt ataactccta gttttttacc aaacctatca aaaaaaatat
    53941 tctgtaaaaa acctctccaa gcatattctt cactaaaaaa aatataaata gtagttaatg
    54001 atgttattgg agtaaatata aattttatga tcccgctata actaggttga gttccttgta
    54061 gtattaagag aaatgatgtt ggaacaatta cagaaatcat aaagtaaata attaacaaag
    54121 aacctgcttt aatatttttt acgggatata aattttttgt atttgatgaa taaattataa
    54181 ttgataaact acttataaaa gttaatatta ggtttataat tgtaaattca ctattattta
    54241 ttagatttag caacctaaga ataattaata atgaataaat aagaaaaaat aatatgatta
    54301 gtgaataaaa tttatacata tcattattta atccttcagt ataaaatttt gcaatagcaa
    54361 ctgaagatag aggtaatatc atcatgaatg atgcaaaatt ttctggatta ataaatttat
    54421 tataatataa tagtaaacct aatgaataag ttaaaccaaa gtttataaag aaaaatatga
    54481 taatttgtaa tttttttctt tttatttcat ttttaataaa tatgggattt agaatattta
    54541 tccagattaa ttttaag
//
LOCUS       DAMKOJ010000017        54261 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.018, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000017 DAMKOJ010000000
VERSION     DAMKOJ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54261
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.018"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            11..87
                     /locus_tag="PC592_001129"
     tRNA            11..87
                     /locus_tag="PC592_001129"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Ile,seq:cat)
     gene            105..181
                     /locus_tag="PC592_001130"
     tRNA            105..181
                     /locus_tag="PC592_001130"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:139..141,aa:His,seq:gtg)
     gene            190..265
                     /locus_tag="PC592_001131"
     tRNA            190..265
                     /locus_tag="PC592_001131"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:223..225,aa:Lys,seq:ttt)
     gene            273..346
                     /locus_tag="PC592_001132"
     tRNA            273..346
                     /locus_tag="PC592_001132"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Cys,seq:gca)
     gene            354..430
                     /locus_tag="PC592_001133"
     tRNA            354..430
                     /locus_tag="PC592_001133"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:388..390,aa:Arg,seq:acg)
     gene            443..518
                     /locus_tag="PC592_001134"
     tRNA            443..518
                     /locus_tag="PC592_001134"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Val,seq:tac)
     gene            594..1007
                     /locus_tag="PC592_001135"
     CDS             594..1007
                     /locus_tag="PC592_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055132.1"
                     /translation="MYIVIGNEIVDSEELKVIIDKNSKFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLISEQCNLASLSDEEKFDEYMTLSDELALNLEELMPKYTIINARAYKL
                     DEVDGVVKIILAVAYADLGHLKLSDVLMRISRQVD"
     gene            1320..4751
                     /locus_tag="PC592_001136"
     CDS             1320..4751
                     /locus_tag="PC592_001136"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDF4055133.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHHEEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKAEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNIKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYSKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPEEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            4993..6921
                     /locus_tag="PC592_001137"
     CDS             4993..6921
                     /locus_tag="PC592_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF4055134.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISNYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLKNSELVEVEKAKAGDIVVVTKINSLK
                     TGDTISIDKDAEALENIDFPKPQIYYAVTPKNKGDEEKVASVLNRLVEEDPTLHSYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGKSDVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFAEEIFGGSVPKQYIPAVEKGIKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASVAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            7378..7842
                     /locus_tag="PC592_001138"
     CDS             7378..7842
                     /locus_tag="PC592_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDF4055135.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGNQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            7849..8343
                     /locus_tag="PC592_001139"
     CDS             7849..8343
                     /locus_tag="PC592_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDF4055136.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            8359..9384
                     /locus_tag="PC592_001140"
     CDS             8359..9384
                     /locus_tag="PC592_001140"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDF4055137.1"
                     /translation="MKENIVMKSRVRLARNLNNYSFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAESDKSAVIVKKDKTVSIMINEE
                     DHIRIQTMCDDLNLEYAYSVANEIDDLLESSLEYAFSTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRIMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            9371..11818
                     /locus_tag="PC592_001141"
     CDS             9371..11818
                     /locus_tag="PC592_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDF4055138.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKGLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWSKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            11998..13371
                     /gene="radA"
                     /locus_tag="PC592_001142"
     CDS             11998..13371
                     /gene="radA"
                     /locus_tag="PC592_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDF4055139.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVTINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     EVVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVIKDTKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            13374..14444
                     /gene="disA"
                     /locus_tag="PC592_001143"
     CDS             13374..14444
                     /gene="disA"
                     /locus_tag="PC592_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HDF4055140.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAITNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            14533..15627
                     /locus_tag="PC592_001144"
     CDS             14533..15627
                     /locus_tag="PC592_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDF4055141.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYFIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKDIKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            15756..17933
                     /locus_tag="PC592_001145"
     CDS             15756..17933
                     /locus_tag="PC592_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055142.1"
                     /translation="MRKKIISFLATFIIILTSASQYIFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSVNENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVVFVELGDTYRLDLYKPNLNEKTYENMKNKIEKNIDVYLKNIFSMVGEND
                     TIYIASAFPSDLDYKNKRRLSPIVKLNGVGKGLLSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKKYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSVIVFSLLILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGAFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILALMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYIIVPMITLSVNLTALKE"
     gene            complement(18112..18963)
                     /locus_tag="PC592_001146"
     CDS             complement(18112..18963)
                     /locus_tag="PC592_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4055143.1"
                     /translation="MNRNSFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCTYHNTSILLQVPMSFLNKYIPDFK
                     NCYFDFKVNANDNNYKRNSSKVKLILENMREIKLSSPPAANLQFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTNINYKSPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILETHGFTNTKLFYRIFKEKFKCTPKHI
                     RKNLPKI"
     gene            19180..20346
                     /locus_tag="PC592_001147"
     CDS             19180..20346
                     /locus_tag="PC592_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HDF4055144.1"
                     /translation="MYIKGVNLGGWLVLEKWMTPSLFEGTEAEDEYYLPRQLSRDVYE
                     SKIKTHRSEYITERDFAIIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFYWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGVCSWSQNPEYVEFTLNVLERLAKRYGMRRELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKDMARRSKPNSLEFLRDFYIKAYKVMRPYMS
                     EENVIVFHDAFELKSWKDFMKEEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIRDN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTAGGQSPLNGIESNIDKLSKDERRELYR
                     KIAKAQIDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            20368..22014
                     /locus_tag="PC592_001148"
     CDS             20368..22014
                     /locus_tag="PC592_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDF4055145.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVFGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDNGKKWISSLDWETREGYEKPGVICL
                     VEYCIEKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHGVTMGR
                     SKNIWGPYEKDLMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETPSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTEDNWLRMEDGSNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNKLGLQYYAPRISPLSFADVNSRTGYVRIRGQESRTSLNRVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIKGRKSYFEWSYDGEKYQRIGETFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIADESKDVD"
     gene            22112..23485
                     /locus_tag="PC592_001149"
     CDS             22112..23485
                     /locus_tag="PC592_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4055146.1"
                     /translation="MNKEVNVKATTIKYEKISFFERVSYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLISRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     ISAILLFSVPSSLGVTSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQDQYERGVL
                     SIFRMILATCGTLIINGLTLPLVEHFGNNLSAWTKTFFIFGIASIIVFFITFTGTKER
                     VKAVKQNKNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFAPINMVSNVSQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIAGQNYIG
                     VISASAIKGIGSAGIAATMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGGVLSIGGYVGTSATQSNSAIVSIKACFIYLPIFITILQIIIMFFYKLDKEYSTI
                     LNELNTK"
     gene            complement(23730..24908)
                     /locus_tag="PC592_001150"
     CDS             complement(23730..24908)
                     /locus_tag="PC592_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055147.1"
                     /translation="MTINHTRLLQTFVELGINSYRQRGTDILKKLYFRFIAYFTTGLF
                     IFLVYFITLFILLNQLIYPEDSHKFLYVIDSSIIYFPSTLIFTFCFITGGILFCLFLV
                     RPLYLIISSISNLSRGNYTISEKAFTKNGKLKWYNFMYREVIINIKDLGNKLQETEIE
                     REKLEVAKTDWLASVSHDLKTPLSYITGYSSLMLNKNHSFSEEEMLTFLNNIYTKGIY
                     IEKLIDELSLTFFIDSHNKIHLKHTQVEIVSFLRNLIADITNNPKSEKHIFEFHTDLQ
                     HLNLVIDETLMYRAIYNLLINCVEHNPSGTEIDVVLTQKSDEIYININDNGIGINPET
                     LNDIFAKYYSSKNQNTQNKGLGLFIVKQIIDAHEGNISVSSIMGKGTSFQIMLKQHKP
                     "
     gene            complement(24832..25566)
                     /locus_tag="PC592_001151"
     CDS             complement(24832..25566)
                     /locus_tag="PC592_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055148.1"
                     /translation="MNDKFKNSERILIVDDEEGLLTLLKITLNKEQYNNITCVSTGAK
                     ALECIENNQYDLIILDVMLPDYSGFDLCTNFRKKTIAPIIFLTARASDYDKLSGLAIG
                     GDDYITKPFNTMELVARIKAIFRRQQLERSVLCNHSENILVYNYGYIVLDMAHALLTV
                     SGKNVECTAKELELLEFFCQNPNRVFTTSHLYDKIWGLQGYGDEKTVTIHISKLRKKI
                     LDDNKPYKVITNLRGIGYKFIPPKGN"
     gene            25734..27185
                     /locus_tag="PC592_001152"
     CDS             25734..27185
                     /locus_tag="PC592_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl protease family protein"
                     /protein_id="HDF4055149.1"
                     /translation="MIKSLKSRGISILLCGALIVGVMTGCTSKATSPKSSTPKSTPKT
                     VEKVTRANCEKQLKEVKAKYKKNPNDEAIRLEYAQILFKLGNITEAQEILNPLLNSKK
                     PSPDAIFLSARIEYLNGNYTQAEKLYDNLIEQYPDKFKSKAEDELALTYYQTNQYQKA
                     DKLSSVKTNNALLEMMKAFKDKHPNKIDWNGKKETVIPFVTGDPLPIIPMEINGKRIN
                     TIIDNGAPMFVVDEKIAEEIGINLASKEENTKFAGGNSIGINFGQANSLTIGDVNMEN
                     IPVMLGPFDGFEKLFKDYGNVHGIMGTTVLKEFVPTMDYPSGQLILRPRNEVGRDNLN
                     KMLTNDKILEEVPFTLASTHFMFGKGSINQKVGLNFFVDSGLGDEKGAGIVLTEEIMN
                     SLKIPMPELKKAEEGKGGMAGSDYKEGYFNLSSYGLGDLQLKNVLGYYFTGDTLDYDE
                     GIGFVRDGLISHHYLKNYKWSIDFDSMKMTFSK"
     gene            27389..28342
                     /locus_tag="PC592_001153"
     CDS             27389..28342
                     /locus_tag="PC592_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDF4055150.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDSLTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            28380..29342
                     /locus_tag="PC592_001154"
     CDS             28380..29342
                     /locus_tag="PC592_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDF4055151.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLRNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            29367..30353
                     /locus_tag="PC592_001155"
     CDS             29367..30353
                     /locus_tag="PC592_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDF4055152.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGVVPEDDYVIEIGKADIKKEGTDVTVITYGRMLQSV
                     EEAAENLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            30366..31412
                     /locus_tag="PC592_001156"
     CDS             30366..31412
                     /locus_tag="PC592_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDF4055153.1"
                     /translation="MVANKVKATPAARNQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTEKETIVSTNTSKFSE
                     KKETKIENENSSMFNTVEGVFEKPNPMRATVARRMSESYFSAPVFTFNIEVDATELKA
                     LRVKLIDTVKESTGVKLTMTDLIVMAVSRILPNHQALNSAWTDEGIFRYKDINIAIAV
                     GLDEGLYVPVVKSVNKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            31579..33309
                     /gene="lpdA"
                     /locus_tag="PC592_001157"
     CDS             31579..33309
                     /gene="lpdA"
                     /locus_tag="PC592_001157"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF4055154.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAAIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEAKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVEVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPKMDKDLSE
                     SLKYSLGKKGINVLTKKKVSEFKEEGNNILVCIEDEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGMNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPADEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            33715..36663
                     /locus_tag="PC592_001158"
     CDS             33715..36663
                     /locus_tag="PC592_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4055155.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSMLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKELQDSDNL
                     KLYKESDDKKEEINNNRENTDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFALESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADESKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETKLTNKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKQKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIVGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LNSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRNISEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEAITIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGIDIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKYNNTKVNFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKVKLNQINNLIDTNQISETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKNPIVWSKNKVKIILLLAVDQKCFNPLSTLLSFIETDEFKQIKNIKDRDFIRE
                     MILDGVNENN"
     gene            36641..37105
                     /locus_tag="PC592_001159"
     CDS             36641..37105
                     /locus_tag="PC592_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055156.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKASYIQ
                     AVIAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            37184..37486
                     /locus_tag="PC592_001160"
     CDS             37184..37486
                     /locus_tag="PC592_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4055157.1"
                     /translation="MGVTNVTKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLIKDVLEKLEL"
     gene            37548..38912
                     /locus_tag="PC592_001161"
     CDS             37548..38912
                     /locus_tag="PC592_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421211.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF4055158.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIIMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMIIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLK
                     KKFGLFGEPLIMGSVIGVIIGVAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSESAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     FIEE"
     gene            38947..39420
                     /locus_tag="PC592_001162"
     CDS             38947..39420
                     /locus_tag="PC592_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055159.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYINFNLNIYSF
                     LIIVCTYGIFNTFISSSNPKKIIIDNKCIHFSSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINEGNLFKGRYWIRTNMFNNSIELYSYLIELEECLYPDSLKFRNKRFENKNI"
     gene            39583..40233
                     /locus_tag="PC592_001163"
     CDS             39583..40233
                     /locus_tag="PC592_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF4055160.1"
                     /translation="MLLDKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLIPSDIVIVDVDGNVIDGKWKASVDLPDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSNKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            40409..41341
                     /locus_tag="PC592_001164"
     CDS             40409..41341
                     /locus_tag="PC592_001164"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF4055161.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVHHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLLTLGLGVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSDKSTESNATKSVSSKVTNIKFLLEKNISYFLDYCVEYLKSNIKNIKELELDEED
                     IKNVYNLVEDKYKKIEWTYGKTPKFQVVLPFNNKSKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            41616..42329
                     /gene="ispD"
                     /locus_tag="PC592_001165"
     CDS             41616..42329
                     /gene="ispD"
                     /locus_tag="PC592_001165"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDF4055162.1"
                     /translation="MYSVIIVAAGSGRRMHLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKELDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERSLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            42326..42811
                     /locus_tag="PC592_001166"
     CDS             42326..42811
                     /locus_tag="PC592_001166"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDF4055163.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIENMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    42906..43113
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            43177..44892
                     /locus_tag="PC592_001167"
     CDS             43177..44892
                     /locus_tag="PC592_001167"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF4055164.1"
                     /translation="MKMSKMFMPTLKEVPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSTEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNVASEKEEMKELEEVYTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGVVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDRDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAEKIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKFRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            45014..46459
                     /locus_tag="PC592_001168"
     CDS             45014..46459
                     /locus_tag="PC592_001168"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF4055165.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRIEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAVCDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            46903..48384
                     /locus_tag="PC592_001169"
     CDS             46903..48384
                     /locus_tag="PC592_001169"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDF4055166.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHDEGVVLDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSIERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALKEKIEKAEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            48605..48760
                     /locus_tag="PC592_001170"
     CDS             48605..48760
                     /locus_tag="PC592_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055167.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            48905..50302
                     /locus_tag="PC592_001171"
     CDS             48905..50302
                     /locus_tag="PC592_001171"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDF4055168.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDGFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            50287..50700
                     /locus_tag="PC592_001172"
     CDS             50287..50700
                     /locus_tag="PC592_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDF4055169.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREHLIRQNTQKK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            50806..51564
                     /locus_tag="PC592_001173"
     CDS             50806..51564
                     /locus_tag="PC592_001173"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HDF4055170.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            51577..52314
                     /gene="rlmB"
                     /locus_tag="PC592_001174"
     CDS             51577..52314
                     /gene="rlmB"
                     /locus_tag="PC592_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDF4055171.1"
                     /translation="MANIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEHKYYELDELIDLVKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLGKSK"
     gene            52317..52844
                     /locus_tag="PC592_001175"
     CDS             52317..52844
                     /locus_tag="PC592_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDF4055172.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            52909..53556
                     /gene="sigH"
                     /locus_tag="PC592_001176"
     CDS             52909..53556
                     /gene="sigH"
                     /locus_tag="PC592_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HDF4055173.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            53630..>54261
                     /locus_tag="PC592_001177"
     CDS             53630..>54261
                     /locus_tag="PC592_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDF4055174.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTD"
BASE COUNT        22052 a         5819 c        10129 g        16261 t
ORIGIN      
        1 aatttaatgt gggccattag ctcagttggt tagagcgccc ggctcataac cggtaggtct
       61 ggggttcgag tccctgatgg cccaccacat taaattaaat tatggtgggt atagctcagt
      121 tggttagagc gccagattgt ggctctggag gtcgtgagtt cgactctcat tatccacccc
      181 aacttatatg gtctattagc tcagtcggta gagcacctga cttttaatca gggtgtcccg
      241 cgttcgagtc gcggatagat caccaaaaag gtggcgacat agccaagtgg taaggcagtg
      301 gactgcaact ccttgatccc cagttcgaat ctgggtgtcg cctccaataa aatgcgctca
      361 tagctcaact ggatagagtg tctgactacg aatcagaagg ttaggggttc gaatcccttt
      421 gggcgcacca tataaatagc gagggattat agctcagctg ggagagcacc tgccttacaa
      481 gcagggggtc acaggttcga gccctgttaa tcccaccagt gcaaacctct agtaatttta
      541 ctaggggttt tatttttgat tgaaaaagtt tttatattta ggaggtaaga aacttgtata
      601 tagtaatagg aaatgaaata gttgatagtg aagaacttaa agtaattata gataaaaata
      661 gtaaatttaa agtagaaaag gatttaagta aaagcacaaa aagagaagat gtaatagcat
      721 atcagttaag tatagattta aattatttag attctcttat aagtgagcaa tgtaatttag
      781 ctagtttatc tgatgaagag aaatttgatg aatatatgac tttgtctgat gaacttgcac
      841 tgaatttaga agaacttatg ccaaaatata caataataaa tgctagagca tataaattag
      901 atgaggtaga tggagttgta aaaataatct tggctgtagc atatgcagat ttaggacact
      961 taaaactttc tgatgtatta atgaggatat ctagacaagt agattaggat acgaatgaat
     1021 atgaactata ttaaaaaaat gtataaaatc ttacgtaaag atgaaaataa ttatgtaaac
     1081 acagaaaaaa acagtataaa atcaagtcaa ttgtagaaat tttcacataa attcatctga
     1141 aattctataa aaaatgcctt aattttaatg aggtaaatcg agtttacaca gtctaaaaat
     1201 tacttatatt tataaattta tcttattaat taaggaactt tcttaaacat cttcaaaaat
     1261 aaagtatttt agtctataat ctttaatatt acacaaacaa taaaggagaa gaatagagta
     1321 tgcttaaaaa gtttaataaa atactagtgg ctaatagagg cgaaatagct ataagaatat
     1381 ttagagcctg ttcagaattg gggataaaaa gtgttggtat atatagtaag gaagataaat
     1441 atggcttatt tagaacaaaa gctgatgaat catatttgat aggagaaggt aaagggccaa
     1501 tagatgcata tctagatatg gatggaataa tagacctagc aaagagaaaa aaagttgatg
     1561 ctatacatcc aggatatggt tttctagcgg agaatgcaga atttgctcgt aaatgtgaag
     1621 agaatggaat tacttttata ggaccatcat ctaaagtaat gaatatgatg ggggataaga
     1681 ttaactctaa aaaaatcgca aaagaagtta atgttcaaac tataccagga gtagaaaaag
     1741 caataagaag tactgaagaa gcaaaggaag ttgcaaacaa aataggctat cctgttatga
     1801 taaaagcatc taatggtggt ggcggtagag gtatgagaat tgtacatcac gaagaagact
     1861 tagagcttga atatgaaact gcttgcagtg aatcaagaaa agcttttgga gaagatatta
     1921 tatttataga aaaatatata gctgatccaa aacatataga agttcaaata ttaggagata
     1981 actatggaaa tatagttcac ttatatgaaa gagattgttc tgttcaaaga agacatcaaa
     2041 aaataataga atatgcacca gctttttcgc tagatgataa agtaagaaaa gagatatgtg
     2101 aagatgcagt taagctatca aaacatgtgg gttattctaa tgcaggaaca ttagaatttt
     2161 tagtagatgc aaatggcgga cattatttta tagagatgaa cacaagagta caagttgaac
     2221 atactgtaac agagatggtt acaggaatag atatagttca aagtcaaata ctaatagccc
     2281 aaggttacag tttagatagt gaagaaatca atataaaatc acaagatgat gtggaaataa
     2341 gaggttactc tatccaatgt agaataacta cagaagaccc taagaataaa ttcatgcctg
     2401 atacaggtaa aattcaagtt tatagaactg gttcagggtt tggtataaga ctagatggag
     2461 gaaatggatt tacaggggca aacataagtc ctcactatga tagtttattg gttaagacaa
     2521 tatcttggga tagaacattc caaggagcaa taaataaaac tataagatct ataaaagaac
     2581 ttagagttag aggtgttaaa actaatgtag gattcctagt taatgtttta aataatccta
     2641 tattctcaaa tggtaaatgt agtactaaat ttatagatga aaacccagat ttatttgaaa
     2701 taacagaaag taaagacaga ggaacaaaat tacttcagtt tataggagat gtaattgtaa
     2761 atgataatgc ttgcaaggaa aagccattat ttgatgcatt acatgaccca agaatggata
     2821 aggatggttc aaaagcagaa ggaagtaaaa tactttttga taagttaggt aaatctgcat
     2881 atatagaaaa gataaaaaat gataagaaat tattattaac agatacaaca atgagagacg
     2941 cacatcaatc attattagca acaagaataa gaacatatga cttattaaaa gctgctaagc
     3001 caacagaaaa atatcaaaaa gatttattct cacttgaaat gtggggagga gctacttatg
     3061 atgttgcata tagattttta aaagaatcac cttggcgtag attacaaaaa ctaagagaag
     3121 aaataccaag tataatgttc cagatgttgc ttagagcatc aaatggagtt ggatataaaa
     3181 actacccaga taatgtaata gaagaattta caaaagaatc tgcgagacaa ggtatagatg
     3241 tatttagaat atttgactca ttaaactggg ttgaaaatat gaaaccatct ataaatacag
     3301 ctttagaaac tggaaaaatt gttgaagcaa ctatgtgtta tacaggtgat atactagata
     3361 agactaaaac taagtataat ctagaatatt atattaaaat ggcacaagaa ttagaaagct
     3421 taggagcaga tataatagca ataaaagata tgtcaggact tcttaaacca tattcagcat
     3481 acactctagt taaagagtta aagaaaaata taaaagcacc aatacattta cacactcatg
     3541 atacaagtgg aaatggtgta gcaacttgtt taatggcatc agaagctggt gtagatataa
     3601 ttgacgctgc attagaatct atggcagggc ttacaagtca accatcactt aatgctatag
     3661 tagaggctct taaaaataca gaaagagata caggtataga tttatttgga tatgatgagt
     3721 taggtaaata ttataaggat ttaagaaaag tttatagcaa atttgaaagt gatttaacga
     3781 actcttgcgc agaaatatat aattttgaaa taccaggagg tcaatataca aacttaaaac
     3841 ctcaagctga tagtttagga ttagttaata gatttgatga agttaaagaa aaatataaag
     3901 aagctaatga agttgtagga gatataataa aagtaactcc atcttcaaag gttgtaggag
     3961 atttagctat ctttatgact aaaaataaat tagataaaga caatataata gaagaaggta
     4021 aaaatttatc attcccagat tctgttgtgg attattgtaa aggtatgatt ggtcaaccag
     4081 aaggtggaat accaaaagat ttacaagaag tagttctaaa aggtgaagaa gctatcacag
     4141 taagaccagg ttcattatta ccagaagaag attttgatga aatagctaaa tatctaaatg
     4201 aaaaatatga tataaatgct aacataagaa atgttataag ttacgcttta tatccaaaag
     4261 tatatgaaga ttatatcaaa catttacaac attataatga tatatctaaa cttgaaagtg
     4321 atgtattctt ctatggatta aataaaaatg aagaatgtga agtggaaata gaagaaggta
     4381 aagtattaac aataagatta gttgaaatag gtgaagttaa ggaaaatgga tttagaacta
     4441 taggatttga gctaaatgga atggttagag aagtagaaat aaaagataag aacttctctg
     4501 gaaaaattaa taatgttgaa aaagctgata tgaatgaccc tcttcaaatt ggagcaagca
     4561 taccaggaaa agttataaaa ataatggtta aagaagaaga tgaagtaaaa gcaaatcaac
     4621 cattaatcgt tatagaggct atgaaaatgg aaactataat agttgccaag actgatggag
     4681 tgattaagtc aatcaaagta aaagaagatg atatggttga agacaaacaa ttattaatga
     4741 taatgaagta attaaattaa aataaactaa aaagcactct gaaatgttta ataaaaaatg
     4801 ttttagagtg tttttattta ttttaattaa atatttgtta aaaaaaagag gacaatcatg
     4861 tccatatgta gaaataaagt tagtaaggaa aatgttatct aaaaattcta aatatagtaa
     4921 atattttccg taatatttct taggaaataa cagcaaagag aaaatacata aatttaaaag
     4981 gtgggtgctt atatgaaggt ttatgatagt aaaatgttga gaaatgtagc ggtattagga
     5041 catagcggat gtggaaaaac aaatctaatc gaaactatag cttacacagc aaacactaat
     5101 aagataccta aattaacaga caaggtaaat atgacttata gcatgggatt aatacctata
     5161 gagtataatg attataagtt taacttattg gataccccag gatattttga ctttagcgga
     5221 gacgttgtgt catctcttag agcaagtgat gcagcaataa tagtaataga tgcaacagcg
     5281 cctattcaag ttggtacaga gaaatcatta gaactaactg agagtattcc taagataatg
     5341 tttataaata aaatagataa tgaaaaagca agatataaag acgcaatagc aatgttaaga
     5401 gaaaagtaca acaataagat agttcctatg ataagtccta tatacaaaga taaaaacttt
     5461 gtaaagttac ataatgtttt tgaaaacata gatgatttag aaggtgaatt taaggaacaa
     5521 gctatgagtg ttaaagaagc attaatggaa cttatagcag agacagatga ccaaatatta
     5581 gataaatatt ttaatggaga agaattaact acagaagaaa tacaaaaagg tattattata
     5641 gggatacaaa gaggagatat tatacctgta atatgtggtt caactataaa taatatagga
     5701 acaaaagaaa tattagatac tatatcaaat tacctagaac ctatttttac ggaagaaagt
     5761 aaaccattta gaggattagt atttaagact atggttgacc catttgttgg taaaatgtca
     5821 tatataaaaa ttactgaagg tgtactttct aaagataaag atgtctttaa tataaataaa
     5881 aatgtaaagg aaaaaatagc taatatatat acattgaaaa atagtgaatt agtggaagta
     5941 gaaaaagcta aagctggaga tatagtagtc gtaactaaaa ttaactctct aaaaacagga
     6001 gataccatat ctatagataa agatgcagaa gctttggaaa atatagattt ccctaagcca
     6061 cagatatact atgcagtaac tcctaagaat aaaggtgatg aagaaaaagt agcatctgta
     6121 ttaaatagac tagtagaaga agaccctaca ttgcattctt atagaaacac agagacaaaa
     6181 caagcacttt taggagggca aggagaactt catataaaaa caattaaaaa taaaatgaaa
     6241 gataaatttg gtgttgatgt tgaattaaat gaccttaaag ttccttatag agaaactata
     6301 aaaggaaaat cagatgtaca aggaaaacat aagaaacaat caggtggtca tggtcaatat
     6361 ggagatgtaa aaataagatt tgaaagatgt gaatctgatt ttgaatttgc agaagagata
     6421 tttggaggtt ctgtaccaaa acaatatata cctgcagttg aaaaaggtat aaaagactct
     6481 atgcaaaaag ggatattagc aggttatcct gttacaaaca taaaagccac gctttatgat
     6541 ggttcatacc atgatgtaga ctcttctgaa atggccttta aaatggcagc aagtgtagct
     6601 tttaaaaaag gtatggaaga agcacatcca atactactag agcctataat gaaacttaag
     6661 ataactgttc cagaagaata tatgggagat gttatgggtg atataaataa gagaagagga
     6721 aaaatatttg gaatggaacc agatgacaaa ggtaaacaaa taatatttgc agaagctcca
     6781 caggcagaga catttaaata tgcaatagat ttaagagcaa tgacacaagg cagaggatac
     6841 tttgaaatgg agctagagag atatggagaa gttccatcac agtttgcgga aaaaataatt
     6901 gggttagcta ctgcaaagta atgaacaaaa ataaatagaa taataagtaa ttaatagata
     6961 ctattaaaaa tatgtttagg attttaacta ggtataagtt tatgttaagt aaacttatac
     7021 ctagttttta tatgttttta atagataaaa aaatataaaa tactttcttg aatattttaa
     7081 taaaaagaaa gtattttatt attattattt ttacaaatgt ttagcaataa agatgagaag
     7141 gtatatttaa aatatagagt atttaaaatg ttgaaatcta atcatgaagc aaaaaaatag
     7201 agtttggtta tcataaatat agtaaataaa aactcgtaat taatgaaaga ataaattcat
     7261 atctaaattt ctataaaaaa tttaaattta tacaatttag ggctttaaaa atttaaataa
     7321 taggtgtaaa ataatagtca aagaaagtca aaaataaaaa ggtgtgtggt gatattaatg
     7381 gcaactatga cagatataat tgaaaaattt attaaagatt tgatggaaga agataatagc
     7441 atacaaattc aaagaaacga actagcaaac ttgtttagtt gtgcaccatc acaaataaat
     7501 tatgtcttaa caacaagatt tacaatagat agaggatatt acattgaaag taaaaaaggt
     7561 ggcggaggat atgttcaaat agaaaaaata cgaaaaagta aagatggaca tattagagaa
     7621 ctgttaaatg aaaaaatagg aaatcaaata tcctataaaa aagcaaaaga attattggaa
     7681 ggtttaaaag agtcagactt gattaacgaa agagaattaa aattaatatt atatgcaata
     7741 gatgataaat cattatgtat gccaatatat gaattaaaag agaaggtaag gtctaatatt
     7801 ttaaagaata taataatagg attatttagt atagaggagt gataatttat gctatgtcaa
     7861 aaatgcaata agaataaagc gtctgtatat tataataaga tagtcaatgg agaaaaaaca
     7921 gagatgtatc tatgtagtga gtgtgcaaaa gagaatacag aaatgaattt taatttagat
     7981 atgccttttt caatgatgga tatattttct aatttaggtt ttcaacctaa aaaagaactt
     8041 gaggaaaagt tagtttgccc taaatgtaat acaacatata gtgaatttaa gaataatggt
     8101 agatttggat gtagtgaatg ttacaatgca tttagtagtc aagtaaatcc aatgcttcaa
     8161 aatatacatg ggcatataga acatacagga aaagcaccta aaaaatcttt ttataaaata
     8221 agtgtagaaa atgagattaa agaattaaaa gaagatttag atagagctat aaaaaatgaa
     8281 gaatatgaat tagcggctca atttagagat aaaattaaat acttaaaagg ttctattgac
     8341 taagattgga gtgatattat gaaagagaac atagtcatga aatcaagagt taggctagct
     8401 agaaatttaa ataactattc ctttccaaat aaattagata aagaatgtgc catggaaata
     8461 atagaaaaag taaaaaatgc atttataaat tctaacttag aacaaaaaga agaatttgat
     8521 ttctataaaa ttgaagattt agaccaatct aaaaaaatgc ttatggttga agaacatata
     8581 ataagcccgg atttagcaga aagtgataaa agtgcagtta tagtaaaaaa agataaaacg
     8641 gtaagcataa tgataaatga agaagaccat ataaggatac aaactatgtg tgatgattta
     8701 aacttagaat atgcatatag tgtagcaaat gaaatagatg atttgttaga atcaagttta
     8761 gaatatgcat ttagcacaaa gctaggttat ctaacatctt gtccaactaa tacaggaaca
     8821 ggaatgagag cctctgtaat gatgcattta ccagcactaa gtcagctagg ttatatggat
     8881 gaactttata aaatttcatc acaaataggt atagcaatta gaggtatata tggagaacga
     8941 acagaagcat taggaaatat atatcaaata tctaatcaac ttacacttgg aagaacagag
     9001 tctaatatta tagaaaatgt aagtggactt acaaaagatg caatttcaaa agaaataaaa
     9061 gcaagagaaa tattgcaaaa aaaattaggt ataaaattag aggataaaat atttagatcg
     9121 atagggacac ttgaaaattc aagaataatg agtagtgcag aggcaatgag ccacctatca
     9181 aatataaaaa tgggaataga aatgaactat atagataaac tagatttaag agctatagaa
     9241 caacttatga taggtataca accagcacat cagtcaataa tgtataagag tgatgatgtt
     9301 gagaatagag atataaatag agcaacatat attagagaaa ctttggaaaa attaagagga
     9361 gggatgaatt gtgaacttca atagatttac acaaagagct aaaaaagcta ttgatttagc
     9421 gtttgaatct gctaaaggtc tagggcataa tattgtcgga agtgaacata tacttttagg
     9481 tcttttaaga gaagaagaag gtatagctgc taaagttcta agtaaagttg gatttacaga
     9541 agcttattta gaaggcaaaa tagttgatat ggaaggtaag ggagaagaaa tctcagaaga
     9601 tatagtatta agtccaagaa gtaaacaaat acttgagtta tcaggcatgt ttgctaataa
     9661 attaaaaaca aattatattg ggactgagca tatattatta gcaattattc aagaaggtga
     9721 aggaatagct aataagattt taaattatgc aggagtaaat gataggactt tagcccaatt
     9781 aacaattgat atgatgggta ttagtgataa aaatcaatac aaagcagaaa atagttacac
     9841 gggcaaccag aatcaagcag aatctaaagt acttgataag tatggaagaa atcttacact
     9901 atatgcaaag cagaataaaa tagaccctgt aataggtaga gaaaaagaaa tccaaagagt
     9961 aatacaaata ttaagcagaa gaactaaaaa taatccagtg ttaataggag acccaggagt
    10021 aggtaaaaca gctatagctg aaggtcttgc tacaaatata gccttaggaa atgttccaga
    10081 aacactaaaa aacaaaactt tatactcttt agagatgggg tcattattgg ctggggctaa
    10141 gtatagagga gaatttgaag aaagaattaa agaagttgta gatgaagttg ttaaaaatgg
    10201 aaacataatt ttatttatag atgagatgca tacaataata ggagctgggt ctactggaga
    10261 aggctctata gatgcttcaa atatattaaa accagcttta gcaagaggag aaatacaagt
    10321 tataggtgca acaacaattg atgaatatag aaagcatgtt gaaaaagatt ctgctctgga
    10381 aagaagattc caaccagtta tggtagatga gccaactaaa gaggactcaa taaaaatatt
    10441 agaaggatta agagataaat atgaagctca tcataaagtt aaaataactg atgatgctat
    10501 aaaggcggct gtagaattat caactagata tatatcagac agatatctgc cagataaagc
    10561 tatagacttg attgatgaag ctgcatcaaa agtaagatta aaagaaaata cacctccatc
    10621 agagataaaa aaattagaac tagaaataga aaatatagat aaagaaaaag aagaagcagt
    10681 aagatgtcaa gactttgaga aagcagccaa aataagagat gaacaaggtc tacttaaaaa
    10741 acaattagaa gatgttagag agagatggag caagtcatct aagcattcag atttagttga
    10801 tggagaagtt attgctgaag tagtaggctt atggacagga atacctgtta ataaaattct
    10861 tgaagaagag gctgatagac ttttaagact cgaggaaata ctacacaata gagttatagg
    10921 ccaagaacaa gcagtaaaat ctatctcaaa ggcaatcaga aggtcaagag caggtcttaa
    10981 agaccctaat agaccaattg gttcattttt atttttaggt ccaacaggag taggtaaaac
    11041 agaattatct aaggcattgg cagaagtaca atttggagat gaaaatcaaa taattagaat
    11101 agatatgtct gaatatatgg aaaagcatgc tgtttcaaga atgataggtt cacctccagg
    11161 ctatgtaggt catgatgaag gtggtcaatt aactgaaaaa gtaagaagaa atccatattc
    11221 agttatctta tttgacgaga tagaaaaagc tcatccagat gtatttaata ttctattaca
    11281 aatcctagat gatggtagac taactgattc aaaaggaaga actgtagact ttaagaatac
    11341 cattgtaata atgacatcaa atgttggtgc atctacaatt ggtagacaaa aaactttagg
    11401 gtttagtata gctaaaggag acgaagaaga aaaatctcag tatgaaaaaa tgaaagaaaa
    11461 tataatgggt gaattaaaac aaagattcag accagagttt ttaaacagaa tagatgatat
    11521 aattgttttc cattcattaa atgaaaatca tatatcaaaa atagtacttt taatggcagc
    11581 aaaactacaa gagagattaa aagaaatgga tataaaatta gaaatgagtg atgaggctgt
    11641 taaattaatt tctaaatctg gatttgactt agaatatgga gcaagacctc ttaaaagagc
    11701 tttacaaaaa gagttagaag atgagttgtc tgaagcaatc ttaaaaggca atgtgaaaaa
    11761 gggaagtaat gtagtagcaa aagtcaaaga tgaaaaaata gtttttgaaa ctaaataatt
    11821 taatagagtt gcattttaaa atattgcaaa tataagcttt ataatctaaa caaaatttta
    11881 agggcaatga atctataata attcattgtc cttaattatt ttatttaatc tttacatatt
    11941 gtctttcaga tatgctaaaa ttatagtata gaataataga ttaaggatga taaaagtatg
    12001 gcaaaaataa aaacaaaata tgtatgtcaa tcttgtggat atgaaacagc taaatggctt
    12061 ggtaaatgtc cagaatgtac aaaatggaat acattcgtag aagaaataga ccaaaaaagt
    12121 accaaaaaag aggtctttat aatagataaa tcttcgtcta aaccagtaac tataaactca
    12181 atagaaagta aagaagaaga gaggtttaca acagatataa atgaattaga tagagtgctt
    12241 gggggaggta tagttaaagg ttctttagta cttgttggtg gagaccctgg tataggtaaa
    12301 tcaacacttt taatccaagt atctagcaat gttgctaatt taggaaaaac tgttttatat
    12361 ataactggag aagaatcaga atctcaaata aaaatgagag ctaaaagatt aggtattaac
    12421 tcagaaaatt tatatatatt tgctgaaaat aatttaagta taattgaatc ttatttagaa
    12481 gttgtaaatc cagaattaat aattctagac tcaattcaaa ctgtcttcag tccagaaata
    12541 tcctcggcac caggaactgt cagccaaatt aaagaaggta cttcaaaatt catgaaaatt
    12601 tctaaaaaaa tgggaatttc aacattcata gttgggcatg ttacaaaaga aggttcacta
    12661 gcaggaccaa aattattaga gcatatggtt gatactgttc tatattttga aggagaaaga
    12721 tataatactt atagattagt aagagctgtt aaaaatcgat ttggctcaac taatgaactt
    12781 ggagtatttg aaatgaggga tttaggatta gtggaacttg ataatccgtc taaaatttta
    12841 atctctgaaa aaccaaaaga tgtagcaggt tcagtaataa tatctactgt agaaggtacg
    12901 agaccaatgt tacttgaatt acaagcatta gtttctccta caagttttgg tataccaaaa
    12961 agaacatcta caggagtcga ttacaataga gtaggtatgt tattagcagt attagaaaaa
    13021 cgtgttggtt tgcaaataca aaatcaagat gtctatataa acatagttgg aggaataaag
    13081 ataaatgaac cttcaattga cttagggata gctatttctg tagcatctag ttttaggaat
    13141 ataccaatag atgaagatat agctgtcaca ggagaagtgg gtcttacagg agaagttaga
    13201 gcagtaagct ttatagaaaa gagaatagct gagtgtaaaa aacttggatt taaaaagata
    13261 gtagttccta gaagtaatta tgatgttata aaagatacca aaggcataga aatatggcca
    13321 gtagataact taagacaagc tataaatata gtgcttggga ggaatcaata aatatggaga
    13381 attttctaga taataaaaat atgctatatg cattaaaaat gatatctcct ggaactccac
    13441 ttagattagg tctaaacaat gtactaagag ctaagactgg tggattgatt gtaattgcaa
    13501 cgaacgaaga tgtaatgaaa atagtagatg gaggatttgc tataaatgca gaatattcac
    13561 catcatatct atatgaatta gctaaaatgg atggagctat agttttaagt ggtgatgtaa
    13621 agaaaatatt atttgctaat gcacaactta tacctgatta ttttatagaa acatcagaga
    13681 caggaacaag gcatagaaca gcagaaagag tagcaaagca aactggtgct atagtcatag
    13741 ggatttcaca aagaagaaat gttataacag tttatagagg aaatgagaag tatgtggtcg
    13801 aagatatatc taagatattt actaaggcaa atcaggctat acaaacttta gaaaaatata
    13861 agacagtatt agaccaagct ataacaaatt taaatgcctt agagtttaat gatttggtaa
    13921 ctatttatga tgtcgcatta gtcatgcaaa agatggaaat ggtaatgaga gttacaagta
    13981 taattgaaaa atatgtgata gaattgggtg atgaaggaac tttagtaagt atgcaattag
    14041 aagaattaat gggtacgacc agaatagacc agaaactaat attcaaagat tataataaag
    14101 aaaatacaga aataaaagaa cttatgaaaa aggtcaaaaa tttaaattca gaagaactaa
    14161 tagaattggt caatatggca aaactattag ggtatagtgg tttttcagaa agtatggata
    14221 tgcctataaa aacaagaggc tataggattc ttagtaaaat acatagacta ccaacagcaa
    14281 taatagaaaa cttagtaaat tattttgaaa actttcaaca aattttagat gcatctattg
    14341 aagaattaga tgaagttgaa ggaataggtg aaataagagc aacatatata aaaaatggac
    14401 ttataaaaat gaaacaatta gtattattag atagacacat atgatgaatt ttaaatgaat
    14461 tttactactt ttttcttgaa tataatatac actttggtct ataataaata agtataacta
    14521 gggggtgaag cattgataag gaaagtaaca agaatattgt ttattttact tggatttaca
    14581 ataggtataa caacctattt aacattaatg aaagattttg aaatattaac atttggaaaa
    14641 gaaacatatg gttatatcgc agctgtagta gcaggtataa taatagccat tttaggatat
    14701 tttatagaac catgggttgt aaataaagta aaagaaattg ctaaaatagt agataaagaa
    14761 ttgtcaaaat atcctcagac tgatatattg ttagggtcta tgggtcttat agtaggattt
    14821 gttattgcat atttattaag tggattagta aatagaatac caatagtagg tggaatacta
    14881 tccttactat tatatttatt cctaggatat cttggaatga aagttgcgct taaaagtaaa
    14941 aatgatttat ttaatattgg aaaactagga agattagcaa atcctattaa ggataaagat
    15001 aaggataaag aaaataaaaa agatataaaa gccattcctc caaaagtatt agatacaagt
    15061 gtaataattg atggaagaat agctgatatt tgtaagactg ggtttataga aggaaaactt
    15121 attattcctg cttttgtttt ggaggaacta agacacattg cagattcttc agatgattta
    15181 aaaagagtaa gaggtagaag aggtctggat atattaaata taattcagaa agaattaaat
    15241 atagaagttg aaataagtga gagagacttt gatgatatag cggaagttga tagtaaatta
    15301 ttaaagcttg ctcaggtttt aaatggaaaa gttgttacaa atgattataa cttaaataaa
    15361 gttgctcaat tccaaggtgt tgaagtatta aatataaatg agttagctaa tgctataaaa
    15421 ccagttgcta taccaggtga ggatatggtt gttcaagtgg ttaaagaagg aaaagaggct
    15481 caacaaggtg ttgcatatct agatgatgga actatgatag ttgttgatgg aggaagaaaa
    15541 tatatgaatg agactataaa agtacttgtt acttctgttc ttcaaactcc tgcaggtaga
    15601 atgatatttg caaaacctaa aaattaatat gttcaaagaa acctataatt tgggctgttt
    15661 attttaaata gatggtccaa atttatttat ttataacgat aatgtttaat gtattcttaa
    15721 agatggggat ttaaatcaga aagcagggag aatttatgag aaaaaagatt atatctttct
    15781 tagcaacatt tatcataata ttaacatcag caagtcagta tatttttgca gatgatatat
    15841 caacacgtgg aaaagtaata tttatagata tgaatagaac tagtatgagt aatatgttaa
    15901 gaataaaatc attaagagaa gaactagaca atagagggta tatcggtttg atgaatataa
    15961 gaggcgataa aggaagtgat gatagacggt catatgctag tatgggtgct ggtggtagag
    16021 ctaatgtggc taatgaagaa gatattaatt ttgaaagctc gagtaaggat agaaatatag
    16081 tttttgaatc agctacagga aagagcgcaa aaggtataaa taatttaact ataaataaat
    16141 ctgtaaatga aaatttaaac tttggagagt atggttctgt attagggtca ttaggacaaa
    16201 gtttatctga taatggacta aaagcatctg tattgggaaa ttcagatata attgaaaatg
    16261 gccaacttat aaaaaataga aacttatgtc taactgcaat ggatgaatat ggaagaatac
    16321 ctaatggaaa tgtagatact ataaataaaa aagacttatc tatgccttat ggaatatcaa
    16381 ctgattatga taaattgatt gtagagacca aagaagctta caaaaataat gatgtggttt
    16441 ttgtggagct tggagataca tatagattag atttatataa accaaattta aatgaaaaaa
    16501 catatgaaaa tatgaaaaat aaaatagaaa aaaatataga tgtatattta aaaaatatat
    16561 tttctatggt tggagaaaat gacactatct acatagcaag tgcatttcca agtgatttag
    16621 attataaaaa taaaagaaga ctttctccaa tagtaaaatt aaatggagta gggaaaggtc
    16681 tattatcatc ttcaactact agaagagaag gtattgtaac aaatttagat gttggggttg
    16741 aaatattaga caactttaat ataaaaaatc aaaatatggt tggaagaaaa tatgaactta
    16801 ttaacagaga tgataataaa gaatttttga tggatgaata tcaaaagata gtatctatct
    16861 caagcataag gtctacaatt ctgaatggtt ttgtaagcat agttttcttg tcatggatag
    16921 ttgctatgat tgcaatttta tttagaaagc atatatcaaa aaaatataaa gaaacaacat
    16981 tttttatatt aaaggaactt ttaaaaatag gaatagtaat gccactgtca tttatgataa
    17041 caccaataat gaatttcaaa acaccattag caatatcttt aggaataatt ataataacac
    17101 ttactatata tcttataagt aaagttttaa taaagaatga tttaaaaaac atgctgtttt
    17161 ttactggatt aactatagta attatggtta ttgatgctgg atttggctca tatttaatga
    17221 aaagcaatgt tatgagttat gactgtataa ttggagctag atattatgga gtaggaaatg
    17281 agtatcaagg tgtggcaatt ggtagtgcaa tatttacatt tgcaatttta cttacatata
    17341 aaaacatacc aaagtggtct gtaatagttt tttctttgct tatcttaatt acaagtgcat
    17401 ctccaattat gggagcaaat gttggaagtg ctatttctga atgtgttgca tttttactat
    17461 ttatactatt aatatataat gtgaagatag acttcaaaaa aattgtatta ttaggtatag
    17521 cagtattatt tgtattagga gcttttgtag caatagatat gattttggga agtaattcac
    17581 atttaggtat gtttgtaaaa gaaatttact ttaatggacc aggagagata atacaaacat
    17641 ttagtagaaa gatagagatg aatttaaagc tagctcaaac cagtgcatgg gtaaatatac
    17701 tgttaactgg aataggggta attttagctc ttatgattaa tcagattaga tactttaagc
    17761 aacttatgga tgagtatcca attgtattta aagggtttat agcatcaata gcgggatgtt
    17821 tagtaactct tttagtaaat gattctggga ttgtgtcatc agctacagcc tttatttata
    17881 taattgtacc tatgataaca ttaagtgtaa atctcacagc attaaaagaa taagcactat
    17941 atgagcacta tgtaaatatg aacacattaa tttaacttcc ttctttattt tataaagaag
    18001 gaagttaata aaaaataaat tataataaaa aagagtttat ctcaaaattg atttttctaa
    18061 tcaaattttg gggtaaactt tttttattat aaaggcaaat aacatataat cttatatttt
    18121 aggtagattt tttcttatat gtttaggggt acatttaaat ttttctttaa aaatcctata
    18181 aaataatttt gtattagtaa atccatgagt ttctaatata ctgcataagg tatcatttgt
    18241 attaattaag tctttataaa tatgagaaat acgtacatca tttaaatact ctaagtaagt
    18301 ttgccccata tattgtttaa attttctaca aaaatattct ggttgtaagt gtgccacctt
    18361 agcaattttg ttaatagaaa taggagattt gtaattaata tttgtatatt ctaaaactgg
    18421 ttcaaatttt gacaaatcaa gtactgtttt tttcatattt ttattaccta cagatatttt
    18481 aaagtttgta tataattcaa ataaaagttc aaataataag cttgtaaatt gcagattagc
    18541 tgctggagga gaactaagtt taatttctct catgttttct aatataagtt taactttact
    18601 tgaatttctt ttatagttat tgtcattagc attaacctta aaatcaaagt agcaattttt
    18661 aaaatcagga atgtatttgt ttagaaaaga cattggtact tgcaataata tagaggtatt
    18721 atgataagta catctagttg agtgaataat tccagaatta atgaacatac actcgttagc
    18781 ttttaagtta taagtgtaac cttccatgtt aatttgtaaa tcaccagagg ttatataaat
    18841 tatttctaat gagttatgcc aatgatttgc tacataacta ccactatcat caaatagttt
    18901 aaaattaaca tctaaattat caataggttc aattatttca tgtgaaaaac tatttctgtt
    18961 cataataatc tcctccttat aactttaaat tataactagt aaatttataa tattcaatat
    19021 taaaaagata atatagacta ataaattaga caataaacat acttaagaaa acagataaaa
    19081 tcaaatataa taactgtata tttaaataat ttaaaaaaat tattttagta taagtgtaaa
    19141 atatacctat ttaaataaga taagagggga ggactttatg tgtatataaa aggtgtaaac
    19201 ttaggaggtt ggttagtttt agaaaaatgg atgaccccaa gtttatttga aggtacagaa
    19261 gccgaagatg aatactactt accaagacaa ctttcaagag atgtatatga atctaaaatt
    19321 aagactcatc gtagtgaata catcacagag agagattttg caataattaa atctatggga
    19381 tttaattcag ttcgtatacc agtaccatat tttatttttg gagattgtga accctttata
    19441 ggttgtgtta aagaacttga taaagcattt tattgggcag ataagtatgg acttagtata
    19501 ttgatagatt tacatacagt tccaggaagc caaaatggat ttgataatgg aggaatatca
    19561 ggggtatgta gctggtcaca aaacccagaa tatgtagagt ttacattaaa tgtactagaa
    19621 agacttgcaa aacgttatgg gatgagacgt gaattgtatg gaatccaaat tttaaatgaa
    19681 cccataacag aaagaatgtg gaatataatg aatgttccaa atcgatttaa ggctgtagat
    19741 aaggatatgg caagaagaag taaacctaat tcattagaat ttttacgtga tttttatata
    19801 aaagcatata aagtaatgcg tccttatatg agtgaggaaa acgttatagt atttcatgat
    19861 gcatttgaat taaaatcatg gaaagacttt atgaaagagg aagaatttaa aaatgttgtt
    19921 ctagatacac accaatattt gatgttagct gaagcagatg gatgtgaaca aagtattgat
    19981 agttatctca aatatattag agataattat gctaaagata ttttacaaat gcaaaagtat
    20041 tttcctgtta tatgtggaga atggagctta tttaattcat atgcttgtgg tatagataca
    20101 gctggaggtc aatcgcctct aaatgggatt gaatcaaata tagataaatt atcaaaagat
    20161 gaaagaagag aattatatag gaagatagca aaagcacaga ttgatgcatg gagaaatgga
    20221 agtggtcact attattggaa ctataagtta ttactagata cagttaatga agaaggctgg
    20281 ataggttggg atagttggga cctaggcaaa tgtgtagctc aagaatggta tcctatagaa
    20341 tattaaacta aaattggagg aaaagatatg attaaaaacc ctatacttcc aggctttaat
    20401 ccagatcctt gtatttgtag aaagggagat gattattatc ttgtagtttc atcttttgaa
    20461 tggtttccag gtatacctgt ttatcactct aaagatttaa aaaattggga gctatacact
    20521 catattttaa cagatgaaac aaaaatagat ttaaagaagc ttccttcatc taaaggaatt
    20581 tgggcacctt gtttgactta ttgtgaagaa gaagatttat tttacatagt ttttggaatt
    20641 atgaactcta tgaatgcaag atattttgat gttgataact atttaattac atcaaaagat
    20701 ataaagggag agtggagtga accagtatat ctacattcat caggttttga tgcgtctatt
    20761 tttcatgatg ataatggtaa aaagtggatt tcgtcattag actgggagac tagagaagga
    20821 tatgaaaaac ctggtgttat atgtttagta gaatactgta tagaaaaaaa agaaatagta
    20881 ggatatccaa agagaatatg gtcaggagga actgatagag gttgtattga ggcaccacat
    20941 ataaccaagc gtggagatta ttattatata atgtgtgcag aaggtggaac tggatatggt
    21001 catggtgtaa ctatgggaag atctaaaaat atatggggac cttatgaaaa agatttaatg
    21061 aatccaattg taacttcaat tccaggagat ttttatgaaa ggcatgaccc tgaccatcta
    21121 aagcctaaat actataatcc agaatcaaag cttcagaaat ctggtcatgg aagctatata
    21181 gaaacaccat caggtgaagt gtatttagtt catctcacat ctagaccatt tgtaccagag
    21241 ttaaggtgta ctttaggtag agaaacagct attcaaaaaa tgaaatggac agaggataat
    21301 tggcttcgaa tggaagatgg aagtaatttg gcaaaagaat atgtatcaga aagtaagcta
    21361 gaagagcatt tagtttcatc tataccaagt tttgatgact ttgattcaaa taaattaggt
    21421 ttacaatact atgcccctag gatttcgcca ttatcatttg cagatgttaa ttctagaaca
    21481 ggatatgtaa ggattagagg gcaagaatca agaacatcat taaatagagt gagcatatta
    21541 gcaagaaagt tgacttcagt atatgcaaga ataactacta aaatggagtt ttatccagag
    21601 gtacatcagc atagcgcagg tttgataatg tattatgata atatgaatta tataaattta
    21661 agaaagtact atagtgaaac attgggtcaa agtgcactat caataataca tcttgaaaat
    21721 ggagagaaaa cagagttttt aaatactagg ataccaataa aagatatacc aatatatctt
    21781 cgtctgtata taaaaggtcg taagtcgtat ttcgaatgga gttatgatgg agaaaagtac
    21841 caaagaatag gagagacatt tgatacaact aagttttcag atgagtactg taaatatgga
    21901 gaatttacag gtacatttat aggattaact tgtgcagatc gtgtaaagca taaacactat
    21961 gctgattttg atttctttga atatatagca gacgaatcaa aagatgtaga ttaataaaat
    22021 tattactaaa atttttagag cataaggtaa aacttatgct ctgaaataag aaacattaga
    22081 aggtaaatct tacaagaagg agtatggtat tatgaataaa gaggttaatg ttaaagcaac
    22141 tactattaaa tatgaaaaga tttcattttt tgaaagagtt tcttatgggt gtggggattt
    22201 aggatgcaat atcatatatt cagcaatgtc agcattttta ttgttttatt acactaatta
    22261 tgcagatgtt agtgcagctg ctgtaggtag tattatgctt atatctagga tattggatgg
    22321 gtttagtgac ttgacaatgg gaattatagt ggatagaact aaatctaaat atggtaaggc
    22381 taggccttgg attttaagaa tggcgattcc ttttgccata tcagcaatat tattattttc
    22441 tgttccatca agtcttggtg tcacttctaa attaatttat atttttatta catataactt
    22501 agtttctact gttatttata cagcaatcaa tgtgccctat gcaactctaa attcacttat
    22561 aactcaagac cagtatgaaa gaggagtatt aagtatattt agaatgatat tagccacttg
    22621 tggtacttta ataataaatg gacttacatt acctctagtt gagcattttg gaaataattt
    22681 atcagcatgg actaaaacgt tttttatatt tggaatagca tctataatag tattttttat
    22741 aacatttact ggaactaagg aaagagtaaa agcagttaag caaaataaga atgaagtaat
    22801 accatttaaa atcggtatta aatctttatt tagaaataag tactggatac aaataacatt
    22861 atgtttagtt tgtatattta ttgtatttgc aataaatggt ggttcatctg tatattatgc
    22921 aaagtttatt ttaggagatg aaaaattatt tgctcctata aacatggttt caaacgtatc
    22981 tcaaattata gctatgttta tggttgctcc ttttataaaa aaatttggga aaagaaatgt
    23041 attaatagta ggttcaataa tattaatatc atcaaatgtt atgtttataa tagctggaca
    23101 aaactatatt ggagtaatat ctgcaagtgc tataaaggga atagggagtg ctggaatagc
    23161 agcaacgatg tttgctattg tttcagatac tattgaatat ggagaatgga agactggata
    23221 tagaactgaa ggtcttataa atagtgcatc tagttttggg tttaaagtcg gaaatggact
    23281 aggttcagca atattaggtg gagtattatc aattggtggt tatgtaggga catcagctac
    23341 tcaaagtaat tcagctatag tatcaataaa agcatgtttt atatacctac ctatatttat
    23401 aaccatatta caaattataa taatgttttt ttataagctt gacaaagaat atagtactat
    23461 acttaatgaa ttaaatacta aataataaaa tattttctat tcagtcttag atttaattaa
    23521 ggattattat agtttattat ttatgaaaaa ctattatata ttcatgatat attaaagcgt
    23581 ttttagaaaa ataaaaaaga aaaactaata ctaaaaatat aaatatatcc agtaaaaaac
    23641 atcttaaaat ctatttattt ggattctaaa agaataaagg agatacctta aaataaaaat
    23701 ttgagttacc tcctttttta ggcaataatt taaggtttat gttgtttcaa catgatttga
    23761 aatgatgtac cctttcccat aatgcttgaa actgaaatat ttccttcatg tgcatcaata
    23821 atttgcttaa caataaataa tcctaacccc ttattttgag tattttggtt tttgctacta
    23881 taatacttag caaaaatatc atttaatgtt tctggattta tcccaatacc attatcatta
    23941 atattaatgt aaatttcatc agatttttgt gttaagacaa catctatttc tgttccagaa
    24001 ggattgtgtt caacacaatt aattaaaagg ttataaatag ctctatacat tagtgtctca
    24061 tcaataacca aatttaaatg ttgtaaatcc gtatgaaatt caaatatatg tttttctgat
    24121 ttcgggttat tggttatatc agcaataagg tttcgaagaa aagaaactat ttcaacttgt
    24181 gtgtgtttaa gatgtatttt gttatgtgaa tctataaaaa acgtcagact taactcatct
    24241 attaattttt caatatatat tccctttgta tatatattat ttaaaaaggt taacatctct
    24301 tcttcactaa aactgtggtt tttgttaagc attagagatg aatatccagt gatatatgac
    24361 aagggggttt ttaaatcatg cgacacacta gcaagccaat cagtttttgc aacttcaagt
    24421 ttttctcgtt caatctcagt ttcttgaagc ttgttgccta agtcttttat atttataata
    24481 acttctctgt acataaagtt ataccatttt agctttccat ttttagtaaa agctttttca
    24541 gatattgtat agtttcctct agataagttg cttattgaac taattatcag gtagagtggt
    24601 cgaacaagaa ataaacaaaa tagtattcct cctgtaataa agcaaaaagt aaatataagt
    24661 gtgcttggga aatagataat agacgaatca attacatata aaaatttatg tgaatcttca
    24721 gggtatatta attgattaag caatatgaat aatgttatga agtatactag gaatataaag
    24781 agacctgttg taaagtaagc aatgaaacga aaatataatt ttttcaatat atcagttccc
    24841 ctttggcggt atgaatttat acccaattcc acgaaggttt gtaataacct tgtatggttt
    24901 attgtcatcc agtatctttt ttctaagttt ggatatatgt attgtaactg tcttttcatc
    24961 gccatatcct tgtaatcccc aaattttatc atacaggtgt gatgtagtaa agaccctatt
    25021 tggattttga caaaaaaatt ctagtagttc taattctttg gctgtacatt ctacattttt
    25081 accacttaca gtaagtagtg catgagccat atcaagaaca atatatccat aattataaac
    25141 taaaatattt tctgagtgat tacataatac agaacgttcg agttgttgac gtctaaaaat
    25201 agctttgatt ctagcaacaa gttccattgt attaaatggt tttgtaatat aatcgtcacc
    25261 accaatagca agtcctgata atttatcata atcactagct cttgcagtta gaaaaatgat
    25321 aggtgctata gtttttttgc gaaaatttgt acataagtca aatccactat aatctggtag
    25381 cattacatca agaatgataa ggtcatattg attattttct atacattcaa gggctttggc
    25441 ccctgttgat acacaggtaa tattattgta ttgctcttta tttaaggtta ttttcaatag
    25501 tgttaaaagt ccttcttcat cgtcaacaat aagtattctt tcagagtttt taaatttgtc
    25561 attcataata attcatctcc cagtatacaa aaatagtatc attataatac catacatgca
    25621 aagtgtaagc aataaattat tcttttgatt ttactttaac tttactttta ttttactttt
    25681 gtactgtatc ttatagataa caagaaagaa aaaaataaaa ataggaggta aaaatgataa
    25741 aatcactgaa atcaagagga ataagtattc tattatgtgg agctttgatt gttggtgtaa
    25801 tgacaggatg tacatctaaa gctacatccc caaaaagctc aacacctaaa tcaactccta
    25861 aaacagtaga aaaagttaca cgtgcaaatt gtgaaaaaca actaaaggaa gtaaaagcaa
    25921 agtataagaa aaatccaaat gatgaagcta tcagattaga atatgctcaa atactcttta
    25981 agttgggaaa tattacagaa gcacaagaaa ttctgaatcc gttactaaat tcaaagaagc
    26041 cttcaccaga tgctattttt ctttctgcac gaatagaata tctgaatggt aattatactc
    26101 aggctgaaaa actatatgat aatcttatag agcaatatcc tgataaattc aaatcgaagg
    26161 ctgaagacga gttggcactt acgtattatc aaacaaatca atatcaaaaa gctgacaagt
    26221 tatcctccgt gaaaacaaat aatgctctat tggaaatgat gaaagctttt aaggataaac
    26281 atccaaataa gattgactgg aatggaaaaa aagaaactgt aattccattt gtaacaggtg
    26341 acccactacc tattatacct atggaaataa atggtaaaag aataaataca attattgata
    26401 atggtgctcc aatgtttgtt gttgatgaga aaattgcaga agaaattggt attaatctag
    26461 cttcaaaaga ggaaaatact aaatttgctg gtggtaatag tattggaatt aattttggtc
    26521 aagccaattc acttaccata ggagatgtaa acatggagaa tattcctgta atgttaggac
    26581 catttgatgg atttgaaaag ctgtttaaag actatggaaa tgttcatgga ataatgggaa
    26641 caactgtatt aaaggagttt gtacctacaa tggactatcc tagtgggcag ctaatattaa
    26701 gacctagaaa tgaagtaggc agagataatc ttaataagat gcttacaaat gataaaatat
    26761 tagaagaagt tccatttaca cttgcttcta ctcattttat gtttggaaaa ggttcaatca
    26821 atcaaaaggt tgggttaaat ttctttgttg attcaggtct tggtgacgaa aaaggagcag
    26881 gaattgtatt aactgaggaa ataatgaatt ccttgaaaat tcctatgcct gagctaaaga
    26941 aagcagagga aggaaaaggt ggaatggctg gaagtgatta taaagaagga tatttcaatc
    27001 tttcatctta tggtctagga gatttgcaac ttaaaaacgt ccttggatat tattttacag
    27061 gtgatacgtt ggattatgat gaggggattg gatttgttag agatggattg ataagtcatc
    27121 actatttaaa gaactataaa tggtctattg actttgattc tatgaagatg acatttagta
    27181 agtaaagata gtatataata tgaattaagt gggaaagttt caactgttca aggaaacggt
    27241 gatacaagaa aagtatcacc gtttttttta ttatacaaaa aacagttgac tttttatatg
    27301 aacccctcct ataatgttac tgaaattaag taaaatgatt gaacaaatgt aaagataatt
    27361 gaaaaagctt gattttggag ggaagcaaat gaaaaaaatt ggagacttaa gattaatgat
    27421 gaagtgttgt tcactttatt atgaagataa tttgaatcag caggaaatag caaatcaatt
    27481 gggaatatca agaccaacaa tatcaagaat attaaaagaa gcttttgaac aagggatagt
    27541 aaaaatacag atagttgatg ttttgaaaaa tgattaccaa aaaatagaga gaagtttgga
    27601 gagaaaatat aaattaaaag aagtaatagt agtagatgat aaacaggatt cactaacaca
    27661 aaaacaagaa ttagcaagag ctgtatctga atatttaacc agggtagtaa aggaaaatga
    27721 tataataggt gtttcaatag gaacaacact aaaagaaata ccaagatatg tggaaaaaag
    27781 taactgtaaa aatgttacat ttatacctct attaggaggg attggagaca atgaaataga
    27841 tattcatgca aatcaaatag cagtaagttt agcaagggcc tttggaggtg attttaaatt
    27901 attacatgct ccagctgtta tgtctgactt atctacaaaa gagaaacttt gcaaagacga
    27961 aaaaattaaa gaagtactag atttaataga taaaacaact atagcaattg tgggtatagg
    28021 aaatcctatg agtttaaact caaccataat ggcttctgga tatatgaatg aagcagatat
    28081 agaagattta aaaaaataca actcaatagg tgcaatttgt ttgcaagctt ttgataaaga
    28141 agggaaaact tctatacttg aatttaatca aagagtatta ggagtaaaac tggaagattt
    28201 aaaaaagata aaaagaacaa taggtgtcgc ttcaggagat gaaaaaatag aggcaataaa
    28261 ggcatcatta aaagcgaaat ttataaatag tttagcaatt aatcacagtt tagcacttaa
    28321 attattagaa gattgtgact aatagaaaga tagataaaag ttaacaggag ggaatatata
    28381 tgtcaatatc aaaagaaaca ttgcttgaaa tgtataagag aatgaatcag gctagaaaat
    28441 ttgaagagaa agttagttgg ttttttgcaa gaggtatggt acatggaaca actcacttat
    28501 ctgtaggtca agaagcatca agtgtggcag ctgtaatggc tttagaaaaa ggagatttag
    28561 tatcattaac tcatagaggt catagtcaat ttataggaat ggggatagac ctaaataaaa
    28621 tgatggctga actaatgggt aaagaaactg gcttttgtaa gggaaaagga ggctcaatgc
    28681 atatagcaga tattgagtca ggtaacttag gagcaaatgg agttgtaggt ggaggtctta
    28741 caatagcacc aggggctgca cttacacaac agtataaaaa aacaggcaaa atagttttat
    28801 gtagttttgg tgatggggca tcaaatgaag gtacttttca tgaaggaata aatttatcat
    28861 caatatggaa attaccaata atattttact gtgaaaataa tttatatggt atgtcaacaa
    28921 gtataaaacg tcatatgaat atagaaagta ttgcaactag agcagcttct tatggaatag
    28981 aggggatatc aatagatgga tataacccaa tagaggtata tgaaacagta caaaaagctg
    29041 ctgaaaagtg tagaagagga gaagggcctg tattaattga aagtaggact tatagatggc
    29101 taggtcattc aaaatcagat gcaaatgtgt atagaacaaa agaagaaata gagtcatgga
    29161 aagcaaagga ccctattgaa tttttaagaa attatcttat agaaaataat ttatctaatg
    29221 aagatgaatt agataagatt caagaatttg caaaacaatc aatagaagat gcagtagagt
    29281 ttgctcaaaa tagcccaaat ccaaaaatag agtctttatt agaggatgta tatgcagact
    29341 aagaatagta aaggaggaaa ataaaaatga gtacaaggga attaacatat gcacaagcaa
    29401 taaaggaagc aatgtcagaa gaaatgagaa gagatgaaaa tgtaatattt atgggagaag
    29461 atataggaat atatggagga gcatttggcg tatcagttgg tatgatagat gaatttggac
    29521 cagaaagagt gagggatact cctatatcag aagcagctat agcaggagcg gcagcaggag
    29581 cagcagcgac tggtttaaga cctattatgg aagtaatgtt tatggacttt gtaacaattt
    29641 ctatggacgc aattgtaaat caggcagcaa aaatgagata tatgtttgga ggaaaagctc
    29701 aagttccaat ggttgttaga tgtccaggtg gttctggaac tggttcagca gagcaacatt
    29761 cacaaagttt agaagcttgg ttttgccatg taccaggagt aaaagtagtt gcaccttcta
    29821 ccccagcaga tgctaaggga ttgttgaaag cagcgataag agataataat ccagtcatat
    29881 ttgttgagaa taaattgtta tacagaaaaa aaggtgttgt gccagaagat gattatgtaa
    29941 ttgaaattgg aaaggcagat ataaaaaaag agggtactga tgttacagta atcacatatg
    30001 gaagaatgtt acaaagtgtt gaagaagcag cagagaatct atcaaaagaa aatataaacg
    30061 ttgaaattat agatttaaga actttatacc cattagataa agagactata gtgaaaagtg
    30121 tatgtaaaac tggaagagtt ttaatttgtc atgaagcagc taagactggt gggttaggtg
    30181 gagaaatatc agccttgata acagaaagtg aatcatttga ttatttagat gctccagtaa
    30241 aaagaatttg tggaaaagat gtgccaatac catataatcc agagttagaa aaagcagttg
    30301 tcccaagagt tgatgaaata gaagaagcaa taaaatcttt aattgttaga taaggaggga
    30361 tagatatggt ggcaaataaa gtaaaagcca caccagcagc tagaaatcag gcaagaaaag
    30421 acaatataaa attagatagg ctgattggaa gtggagagaa tggaaggatt catttagtgg
    30481 atgtgttaaa ttatttaaaa gataacaaag caaatactac tcctttagct agaagaatag
    30541 cagaagattt aaatatagat ttagaaacta ttgtaggtac tggatataat ggaaagataa
    30601 gaaagtgtga tgtggaaaaa ttaactgaaa aagaaactat tgtatcaact aatacgtcta
    30661 aatttagtga gaaaaaagag acaaagattg aaaatgaaaa ttcaagtatg tttaatacag
    30721 tagaaggagt atttgaaaaa ccaaatccaa tgagagccac tgtagcaaga cgaatgtcag
    30781 aaagttattt tagtgctcct gtatttacat tcaatataga agtagacgct acagaattga
    30841 aggcacttag agtaaagtta atagacacag taaaagaatc aactggagta aaattaacta
    30901 tgacagattt aatagtaatg gcagtatcta gaatacttcc aaatcatcaa gcattaaact
    30961 cagcatggac agatgagggt atatttagat ataaagatat aaatatagcc attgcagttg
    31021 gtctagatga aggtttatat gttccagtag taaaaagtgt aaacaaaaag tctttaaaag
    31081 aaatagcaaa agaaagcaaa gaacttgccg aaaaagtaaa gacagggaaa cttatgccag
    31141 cagaccaaga aggtaataca tttacaataa gtaatgtcgg aatgtatggt ataactacat
    31201 ttacacctat aataaatatg ccttcaagtg caattttagg ggtaggtgct acacaagata
    31261 agtttgttcc agtaaatgga gaggctaaaa taaaacctat aatgaactta tcattgacat
    31321 cagaccacag agtaatagat ggaacagtag ccgcaaaatt cttaaaagat ttaaaagaat
    31381 tgttagaaaa tcccttatca atgcttgtat aggttttgac atttcgttac tgatataaat
    31441 agtttgaata gattatatta ttataattat ctcagtaaat ttaaaacttt tatatattga
    31501 gaattatttt taaaggtaac tgtatatgaa tatgatttgc ttaattaaaa tatatgaaaa
    31561 taaataggag gagagcctat gtcagtagaa gtaataatgc caaaagcagg tgtagccatg
    31621 gaagaaggta ctatagtatc ttggctaaag caagaaggcg aagaagtaaa gattggagaa
    31681 cctatattag aaataacaac agataaagtc aatatggaga tagagtcaga aggagaaggt
    31741 acacttgctg caatcataca taaagaggaa ggtgaagtat taccagtatt tacagtaata
    31801 ggtgtaatag cagaaaaagg agaaaatcaa gaggaagtaa aagctaaata tttatctgga
    31861 aatgtttcaa aagaagatat agttgaagag aatcaaaaca tagaagctaa agaagaaaaa
    31921 ataaacaaaa aagagtgtaa tcatgattat gatgtagtgg taataggtgg aggacctggg
    31981 ggatatttat cagcattaaa agcagctctt ttaggtggaa gagttgcttt agttgaagaa
    32041 aatatactag gaggtacttg tttaaataga ggttgtatcc ctacaaagac ttatataaaa
    32101 acggcagaaa tattagaaga aattgaccag ttatcaaaga gaggcgtaaa agtaactgta
    32161 gataaagaac aggacattaa gaaggctata aaatataaaa atagagtagt taaaaaactt
    32221 acagctggtg ttggtggact attaaaaagt agagatgtag aggtgtttaa tcttaaagct
    32281 agtgttaagg aagagcataa agtaatttta tcagatggaa aagttttaga tacagaaaat
    32341 ataataattg ctacaggttc taaggtaaga atattaccta taaaaggaat agaatcaaat
    32401 ttaataataa ctagtacaga agctttagat ttagaaacag taccagaaga attagtaata
    32461 attggtggtg gagtgattgg ttgtgaattt gcagagatat tcaattcaag aggctctaaa
    32521 gtaactatag tagaaatgga agatagagta attccaaaaa tggataaaga tttaagtgaa
    32581 tctttaaaat attctcttgg taaaaaaggt ataaacgtgc taactaaaaa gaaagtttct
    32641 gaatttaaag aagaaggaaa taacatatta gtgtgtattg aagatgaaga accaataaaa
    32701 gcagatttat gtctatatgc tataggaaga gaagctaatc tttctggtat agaggactta
    32761 gatattaaaa tagataaagg ttcaatagtt gtaaatagca aaatggaaac aagtatacca
    32821 agcatatatg cagtaggtga tgtgactgga ggtgtaatgt tagctcatgc agcttttaaa
    32881 atgggagagg tagcagcttc aaatgctcta ggtatgaata aagaagttga tttaggtgca
    32941 ttacctagtt gtgtttatac aattccagaa gtagcatcag ttggtattac agaagaggat
    33001 gctagaaaaa aatataatgt aaaagttggt aagtttaatt ttgctggaaa tggaagagcc
    33061 ttagcttctg gtcaagaaca aggatatgtg aaagtagtag cagatgctaa atatggagaa
    33121 attttaggta tacatatgtt tggatgtggt gtagcagaac ttataaatca tgcagcatca
    33181 ttcaaagcat tagagatacc tgctgatgaa gctagtgagt taatttttgg tcatccatgc
    33241 acttcagaag ctttgatgga ggctttagca gatgtaaatg gagaatgttt acacttacct
    33301 aaaaaataaa ttgttaatgt aagtctatta ttaatgttaa tttatatcat aaagttttaa
    33361 aagaattact tagccatacc ctttgttgta caaataaatt atttgcacaa caaagggtat
    33421 tttttatgga aaaatatata gtatgaaacc tttgtagttt ttgttataca aaaaagatag
    33481 taatataaaa taacagtatt attttagaat gatttcaatt gtaattagaa aaaatgattt
    33541 ttttgttttt aagaaaagta ttatttgtaa aatgtaaaaa aaattttctt aatatttcaa
    33601 taaaagaata gcttgattta aatgttatta ctttataaaa aaataataag cacaaaaaaa
    33661 acaatatatg gcatataagt tgctatataa ataataagga gggaacaatt ataaatgagg
    33721 caaagaataa aaaacttaat tgaaaatgaa gataaaaaaa atcctttaac agatgaagcg
    33781 atttcaagta tgttaaatat tcgaagagaa gatgttacct ttttaagaaa tgagttaaaa
    33841 atagaagatt caaggcaaag aagaaaagtt gttttaatta aagctataaa agacatttta
    33901 aaagaagaaa aaactataaa taaaaatgat ataacaagaa gattaaacag cattggtttt
    33961 acagtatcaa gatttacagt tatacagtac ttaaaagagc ttcaagattc tgataactta
    34021 aaactttata aagaaagtga tgataaaaaa gaagaaataa acaataatag agaaaacaca
    34081 gatatagcat ttgataaact cataggtagt agtggtagct taagtacaat tataaaacta
    34141 gctaaagcag caattctata tccacctcat ggtcttcata ctatcattat gggaccaact
    34201 ggtgttggaa agagtgagtt agcagagtgt atgtataaat ttgcactaga atcatccaga
    34261 ttccctaaga atgcaccatt tatagttttt aatgcagcag attattcaga gaatccacag
    34321 cttttgttat cacagttatt tggacatgtt aaaggtgctt ttacaggagc tgacgagagt
    34381 aaagaaggat tagtatcaaa ggcagatgga ggaatactgt ttatagatga aatacataga
    34441 ttacctcatg aaggtcaaga aatactattt caattgattg ataaggggat ggtcagaaaa
    34501 ttaggagaaa caaaactaac aaataaaata gatgtaatga ttatttcagc aacttctgag
    34561 ccaatagatt ctcatttact taatacattt aaaagacgta tacctgtaac aattgaaata
    34621 ccagaattag ttgcaagacc attaaatgag aggtttgata ttataaataa tttcttctta
    34681 atagaagctc aaagaatggg agcaaacata catataaagt cagatgtatt aaaagctctt
    34741 atgctttacg actgtatagg taatgttggt caactgagaa gtgatattca agtagcttgt
    34801 gctaggggac tactaaatca acttacaaat aaacaaaaag aagtaaacat aagcatatca
    34861 gatgtacctg gatatgttaa acaaggtctt ataaaaatca gaaattgcag aggtaaaata
    34921 gaaaattatg tagatggaga cttaattata gactcaaatc ttcaaggtga aatagaaaag
    34981 aaaaatgaag acatatatac ttttccagat gaaatatata aacttactga aagaagacat
    35041 attgatttat tggaacaagg tttagatttt gatgttataa atagaatcgt tggaggagaa
    35101 ttagaaagtt gcattcaaaa atacataaag caagttaaaa aagtttctat tagtaataat
    35161 cttccagata taagtccgat tgttggaaaa tatatagtag agctaactta tgaagtaatc
    35221 aaaatagcat cacaatatct taattcatta gaaccaaatc tacatttatg tttagcagta
    35281 cacttaaaag ccgcttttga gagattaaaa gaagggaaag taatatcaaa tgctcatttg
    35341 aaagaaataa taggaaatta tccactagaa tattctgtag cagaaaaggt ggctcaatat
    35401 ctaaaggaaa gatataacat aaatttgcca aaagaagaaa taggtataat agcaatatat
    35461 tttaaaatga gtagcagaag aaatatatct gaacaaaaaa agataggtgt acttcttatg
    35521 gctcatggaa gggtagcatc ttctgtatgt gaggttacaa ataaactatt aggaattaat
    35581 catgcaaggt atttagatat gccatttgag aagaaaccag aagaaatgat tgaagaagct
    35641 attacaataa taaaagatat tgatgaaggt agaggtgtaa ttatactagt agatatgggt
    35701 tcactttcat attttggaga tattatttct ggaaagactg ggattgatat aagaacaata
    35761 tctagatttg atacattgct ttctatagaa gttatacgaa gagcagtttt accagattta
    35821 acaatagacg agatagttga tgaagttaaa ggtatagagc cacaagtaaa agaaaaagtt
    35881 agtaaatata acaatacaaa agtaaatttt agaaaaccta taattttaac attatgtatt
    35941 actggattag ggggagcttg taagataaaa aaaatcctag aggaaaatat taaaagtata
    36001 actgaaaagg ttgatataga gcctataggt atgattgaat atccaagtct tgatttagag
    36061 ataaaacaaa taagtaatga taaaaatgta attgccatag ttggaacaat tgaccctcag
    36121 atagcaaata tccctttttt tagcctagta gatataaatg ataaagtaaa gttaaatcaa
    36181 ataaacaatc taattgatac aaatcaaatt agtgagacaa ataaaaaata tgaattatca
    36241 gatttaatac ataaagaaga tatattcgta gatttacaag ttaaatccaa agaagaagtt
    36301 ctaaaatata tgagtaaaaa acttagagag aaaggttacg tgacaaaaaa tttctataaa
    36361 aaagtagtgg aaagagataa cttatttcca actgaattat cagatgaaat agcaatacct
    36421 cacacagatg gaatagatgt aattagacca gctataagca tagctatttt aaagaatcct
    36481 attgtgtgga gtaaaaataa agtaaaaata atacttttat tagctgtaga ccaaaagtgt
    36541 tttaatccat taagcactct actttcattt atagaaacag atgaatttaa gcagataaaa
    36601 aacataaaag atagagattt tattagggag atgatattag atggagtcaa tgaaaataat
    36661 tagtagtaat ttaattttta aaaatattga agtgtctaac aatgaagatg cattaaagtt
    36721 tttgggacaa cgtttatttg atgaacagta tgtaaaggca agttacatac aagctgttat
    36781 agcaagagag aaaaagtatg ctacaggatt accaacagaa atatatggag tggcaatacc
    36841 acatacagat atagtacatg taaatgagcc aggaatagca attgggatac tgaataaacc
    36901 tgtaaaattt ataatgatgg gtacagatga tacagagatt gatgtaaaag ttgtatttat
    36961 gttagccgtg aaagagccac aagaacaatt gcaactatta gaaaaactta tgactatatt
    37021 tcaagataag aatatactaa ataatattgt tgacttaagc gaagaaagtg tgagtgattt
    37081 attaaactct aaattgaaaa attgaatata taaagtatat taaaaaataa aaatgttatt
    37141 gaagatttct aactataggt atctttaaaa taaaataatt tcaatggggg tgactaatgt
    37201 gactaaaaag atattagttg catgtggaac aggagtatgt acttcaacaa ttgctataaa
    37261 caaattaaag aaagcgcttc aagatattgg taaattggat atggttaata ttacacaatg
    37321 taaagtggta gaagttgcat caaaagcacc tgattatgat ttaataattt gtactacaca
    37381 agtatctagt agtataaaaa caccagtgat aaatggatta ccttttttaa ctggtgtcgg
    37441 aatggataaa ttaatcaagg atgtattaga aaagctagaa ttataatcaa aaaaattaag
    37501 gaacatggtc tctaaaatta taagttttag agacttaaaa ttaaataatg gagggtcttt
    37561 atatggagat attaaatttc attgttggtc taggcgcaca agtaatgatg ccgataataa
    37621 tatgtatttt tggtttgata ttaggtacaa aactaggaaa atctttaaga gctggtttaa
    37681 ctgtaggagt tgggtttata ggtcttaata ctattatagc tttgctaaca gataatttag
    37741 gtccagctac acaacaaatg gttaagaatt taggactaag tttatccata atagatgtag
    37801 gatggccagc agcatcggcc atagcttttg catcaacagt aggggcttta attattccaa
    37861 taggtcttgt ggtaaatata attatgttaa ttactaatac cactcaaact gttgatgtag
    37921 atatatggga ctactggcat tttgctttta caggagcttt agtggcaggg gctactcaaa
    37981 gtgtaatgtg gggagtattt gcagcagtag caaatatgat aattgtattg gtaatggcag
    38041 atttaactgc tccagggata gaggaatatt taggtatgcc aggtatatct cttcctcatg
    38101 gatttacaca agcatttgtt ccaattgcta tagtagtaaa taaattatta gacctaatac
    38161 caggcataaa taagattgag ataaatgctg atacattgaa gaaaaagttt ggattatttg
    38221 gagaaccttt aataatgggg tctgtaatag gggtaataat tggtgttgca gcgaaatatg
    38281 atataaaagg aatattacaa ttaggtgtaa ctatgggagc agtattaata ttaattccaa
    38341 agatggcagc gttattaatg gaaggattat taccagtatc agaatctgca caggaattta
    38401 ttgaaaagag atttaaaaat agaggtaaga tttacatagg cttagattca gcagtaggaa
    38461 taggtcatcc tgttacacta tcagttgcat tagtgttggt tcctttgact atacttatag
    38521 cagctatatt gccaggaaat aaagttttgc catttgcaga tttagcagta attccatttg
    38581 cacttgtatt aattgtgcca attacaaagg gaaatgtgtt tagaacatta ataataggaa
    38641 taattataat tacttctggg ttattaatcg caactaattt agctccatta tttactcaaa
    38701 tggctttaaa tgctagtttt aaaatgcctg aaggagcaac tatgatttca agtatttgtg
    38761 atggtgcgaa tccattaagt tgggtatttg taaaagttat gaactataaa gttattggag
    38821 gagtagtttt tggagtcata gctttaggaa tggctattta caataggaat agaataataa
    38881 atgaaaataa aaagctattt atagaagaat aaggttaaaa caattttatt aaggagtgta
    38941 taagttatga aaaaatataa atatgattct aaaaggtact tacttagcgt tacaatacca
    39001 ggatttttta tgattttaat attgatttat gcactgttta ataactatat aaattttaat
    39061 ttgaatatat atagtttttt aataattgtt tgtacttatg gtatattcaa tactttcata
    39121 tcatcaagta atcctaaaaa aattattatt gataacaaat gtatacattt ttcttcattt
    39181 atgactacac ataagtatga aattaaagat atagaaaaga taagaataag agaattttat
    39241 aataaaaaaa tttatctaaa aattaatgaa ggaaaccttt ttaaaggtag gtattggata
    39301 agaacaaata tgtttaataa tagtatagaa ttatatagct atttaattga gttggaagag
    39361 tgcttatatc cagattcatt aaagtttaga aataaaagat ttgagaataa gaacatatag
    39421 aaataaaaaa attaaattga agcctagttt aatatgtttt gatagaatat gagtttgagc
    39481 ttcatgctga atttttagaa ttttcaatta aaataataat ataatgtcta agcaattaga
    39541 gacgtataag gcatgtatat aatgaatggg aggatttaat taatgttatt agacaaatta
    39601 agaaaagaag tattacaagc atctttagac cttttaaatt ataatttagt gacattaaca
    39661 ggaggaaatg taagtggtag agatgaacaa actggctata tagcaatcac cccaagtgga
    39721 atggattata gaaatcttat accaagtgat attgttatag tagatgtaga tggaaatgtt
    39781 atagatggaa aatggaaagc atcagtagat ttaccagacc acttgtatat atataaacat
    39841 agagaagaca taaatagtat aattcataca cattctacat actcaagttg ttttgctatt
    39901 ttaaatgaac ctatagaatg tgcaagtaca actcttgcaa atgaagtagg aggttcagta
    39961 ccagttgcaa aattttcacc accaacgtct aataagatgg gaaaatgtgt tattgaagca
    40021 attggtgaca aaagagcatg tcttttagca aatcatggtg taattgcagt tggtccatct
    40081 gtaggacacg ctcttacagc tgctgtaatg ttagaagatt cagcaaaagt atattactta
    40141 gcaaaatcaa ttggcacacc agtgctactg cctgatgaag aaattcaaag agctagagat
    40201 gtatttttta atgtctatgg tcaggataaa taaacgagat aaaattttaa aagtaatatt
    40261 aaaatataga tattcaatga tattaaggag atttataatg atataataag tttaatagtt
    40321 aagaagtaaa atatgaaatg taatcgtata taaattcact taagactaac aaataataag
    40381 ataaaataaa aaaggagtct gtatttctat gtattactta ttaaacaaaa gcacaaatcc
    40441 ttactttaat ttagcattag aagaatatct gtttttaaat gataaatata atgatgatat
    40501 tataatcata tggaggaatg aagaatccat ttttataggt aaaaatcaaa atccatatca
    40561 ggaagtacat catgatgtta ttgaaaaggg cgaaattcct attttaagaa gaatatctgg
    40621 aggaggcact gtttatcatg atttaggtaa tattaatatg tcattcatac aaaaagatag
    40681 acaacttcat gagatagatt ttttggagca tactaagttt atgcaaaaga tgctcttaac
    40741 cttgggatta ggtgtatcta taactgaaag aaaggattta tttttaaatg ggaaaaaaat
    40801 ttcaggctct gcacagtcta taaaaagaaa aaattctctt tatcatggaa ctcttcttta
    40861 cgattcagat ttaaataaat tgactaagta tttaaactca gataaatcaa ctgaatctaa
    40921 tgcaactaag tctgtttcaa gtaaagttac aaatattaag tttttgctcg aaaaaaatat
    40981 aagttatttt ttagattatt gtgttgaata tttaaaatct aatataaaaa atataaaaga
    41041 acttgaatta gatgaagaag atattaaaaa tgtatacaat ttagtagaag ataagtataa
    41101 aaagatagag tggacatatg gtaaaacgcc taaatttcaa gtggtgctac catttaataa
    41161 taaaagtaaa attaatatac atgttaatag atggaaagta tcaaaatttt ttatttctta
    41221 tgatgataat gtaattaata tggacaagtt gttggattta aatttcttta aagaagaaat
    41281 aaaagagagt attttagaaa attatccaca ttacatagat ttaattaatt taatatttta
    41341 atataaaacc tctaatttga taaaattgtc ttatatcaaa ctagaggttt ttaatatttt
    41401 tacatatcaa taaccattaa aaaattgtaa aattaaaaac aatactattg aaaaatcaat
    41461 atatattgta ataaatatac atgtttttca ttagtaaata gacattagct atttatacaa
    41521 ccgaaaattt aatatataat taatcagatg gttaaaataa aaaatattaa aagttttaat
    41581 aaatgatggt taaaaataaa atacgaggtg ataccatgta tagtgttata attgttgcgg
    41641 caggaagtgg aaggagaatg cacttagaca taaacaaaca gttcataaaa ttaagagaaa
    41701 aagaaattat tgctcataca attcaagttt tttatgaaaa tataaatata gatgaaatag
    41761 tggtatgtat aaagaaagaa gaagaagatt tttttaagga aaacataata aataaatata
    41821 attttaaaaa cataaaaata gcatatggtg gaaaagaaag acaggattca atatataatg
    41881 gtttaaaaga attagataaa aattgtgata tagtacttat acatgatgga gcaaggccat
    41941 ttgtagacca tagaataatc aacgaatcaa taaaggtagc taaagaaaaa aaggctgtgg
    42001 ttgtaggtgt tccagtaagt gatactataa agatagtatc agatggaaca gtacaagaaa
    42061 ctccagaaag aagtttgctg tgggcagcac aaacccctca aacatttgaa tataatctca
    42121 taatagatgc ttatgaacaa gcatataaaa ataattatta tggtactgat gattcaatgt
    42181 tagtagaaaa tataggtcaa agtgtcacta tggtaatggg ttcatatgaa aatataaaaa
    42241 taactagtcc agaagattta aatatagcag aacaaatatt aaatatggaa aaaagagatg
    42301 aagttaatag tagaaggaga attatatgag aataggatta ggatatgatg tacacaaatt
    42361 aacagaggat agaaagctta taatcggcgg tgtagagata ccgcacgata aaggtttgtt
    42421 ggggcattct gatgctgatg tattgataca tgcaataatg gattctattt taggtgctct
    42481 agcattagga gatataggga aacatttccc agatacagat gaagaatata agggagcaga
    42541 tagtatgaaa ttattagaac atgtgtataa tctaataaca agtaaaggat ataaaattgg
    42601 aaatatagat agtactataa ttgctcaaag tcctaagatg gctccataca ttgagaatat
    42661 gagaagtaat atatcaaaag ttttaaacac agacattgat aatataaaca taaaggcaac
    42721 aacagaagaa ggtcttggtt ttacaggagc aaaacaggga atagcttcac aaagtatttg
    42781 tttattattg ttgacaagtc agaataatta atatattatt agtaataagt ttaatggata
    42841 tcaagtaata ggcctatata gaatatctat aatgtgtgaa tttaagtgaa attaatataa
    42901 atataaaatt agctatgata aagaaatagt aaatgatgaa atcttcacag agaggaaacg
    42961 gtggtgagag ttttcaagag gaagtctttg aacctgtctt ttagcttaaa ggtataaaaa
    43021 tctttacggt aggaaccgtt atattcccaa aagagagcta ttcatatagc taactagagt
    43081 ggtaccgcgg aaattaaacc tttcgtctct atacttgtat agagatgaga ggttttttat
    43141 attttcagaa agttaatatt caggaggaat ctattaatga aaatgtcaaa aatgtttatg
    43201 ccgacattaa aagaagtccc agcagatgct gagattacaa gccatcaatt aatggttagg
    43261 tcaggcatga taaaaaaaat gacttcaggt gtttataacc aattaccaat ggggttaaga
    43321 gtgttcaaaa aaattgaaca aataattaga gaagaattaa ataaaaaaga ttgtcaagaa
    43381 atactttgtg cagccttact tccttctgaa ttatggaaag agtctggaag gtggactgct
    43441 atgggtgaag aaatgtttag attaaaagac agaacagaaa gagagtattg tcttgggcca
    43501 acacatgaag aagcattcac tgacataata agacaagaaa ttacttcata taaacaattg
    43561 ccactgaact tgtaccaaat acaagtaaaa tatagagatg agagaagacc aagatttggt
    43621 gttatgagaa ctaagacttt tacgatgaag gatgcttata gttttgatgt agatgataaa
    43681 ggtctagata agtcatatca agatatgttt gatgcatatg taagtatatt tgatagatgt
    43741 ggattggaga atagccctgt acaggcagat tcaggagcta taggaggttc tacatcaact
    43801 gaatttatgg ttaagtcaga agttggtgaa gatgaagttg tattttgtag tggatgtgac
    43861 tatgcagcca atgtagaaag agcagaatct tgtaatgtag catcagaaaa agaagaaatg
    43921 aaagaattag aagaggttta tacaccagga gcagctacaa taaaagagct agaagaattt
    43981 ttaaaaactt ctccagataa gtttgctaaa actttagtat atgaggcaga tggaaaaaca
    44041 gttgtagtcg ttgtaagagg tgatagggaa gttaatgaaa tcaaagtatc taatgctatt
    44101 ggctctgtta tagaatttgc acttgctaca gatgatgtag tgagaaaggt gactaatgca
    44161 gaagtaggat ttgcaggacc aataggtata aatgctgatt atgtatttat agataaagaa
    44221 attgttgaac aaagaaacat agttgttggg gctaataaaa ctgagtacca tataaaaaat
    44281 gctaactatg gaagagattt tgaaggagta gttggagact ttagaaatgt tcaagaaggc
    44341 gacaaatgta tagtatgtgg taagccactt gaaatagcta ggggtgttga agtaggacat
    44401 atatttaaac taggaactaa gtactcagaa tctatgaatg caaacttcat agacagagat
    44461 ggaaaatcaa agcctatagt aatggggtgt tatggaatag gtgttgaaag aacagcagca
    44521 gctataattg aacaacataa tgatgagaaa ggtataatat ggcctttatc agtagctcca
    44581 taccatgttg tgatagttcc agcaaatatg aagaatgaag aacaaatatc aatagctgaa
    44641 aaaatatata atgatttaca ggctatgggt gtagaagttt tattagatga cagagatgaa
    44701 agaataggtg tcaaattcaa tgattcagaa ttaataggaa tacctatgag aattacagta
    44761 ggtaaaaata ttaatgaagg taaagtagaa tttaaattta gacataaaga agataaagag
    44821 ataattgaca tagaagaaat aaatgaaaaa gtaaaggcag agtttatcag aaataatgtt
    44881 aggttaggat aataacttaa ataagatatt gtatagataa tcagagttgt actttataga
    44941 caccatttta tctatatata aggatataaa atggtgtttt tttataaaac aaataaatga
    45001 ggaggtaatt gaaatggcaa aaaatgaaaa acaatttgtt gaagaaataa caaagatgga
    45061 agatgatttt ccacaatggt acacagatgt aataactaag actgacttag ttgattatgc
    45121 accagtaaaa ggttttatgg ttgtaaagcc atatggatat gcattatggg aaaagatgca
    45181 ggaatttatg gataaaaaat ttaaagaaac tggacacaaa aactgttatt ttccattatt
    45241 aataccagag agtttattaa acaaagaagc agaacacgtt gaaggttttg ctccagaagt
    45301 tgcatgggta acacatggag gaaataaaaa attagaagaa agattatgtg taagacctac
    45361 ttcagagact ataatatgta caatgtatgc gaagtggtta aaatcatata gagaattacc
    45421 atacctttat aatcaatggt gctcagttgt tagatgggaa aaatcaacta gacctttctt
    45481 aagaacatct gagtttttat ggcaagaagg tcatacatta catgaaacag cagaagaagc
    45541 acaagaagaa acaatacaac aattagaagt atataaagca ctatgtgaag aattacttgc
    45601 aatgccagtt gtagctggtc aaaaaagtga aagtgagaaa tttgcaggtg gtgaaagaac
    45661 atatactata gaagctatga tgcatgatgg taaagcatta caatcaggta caagtcactt
    45721 cttaggtcaa cactttacta aggcttttga tattactttt gcagatagag aaggaaactt
    45781 agctaatcca tatcatacat cttggggagc atcaacaaga cttataggtg gacttataat
    45841 gactcatagt gataacagag gtttagtatt accaccaaga gtagctccaa ttcaagttgt
    45901 tatagttcct atagctgcca aaaaaggaaa tgtaatggaa actgttgata aaatatatgc
    45961 tgatttaaaa gctaagggag tagctgtaga agttgatgat agagataact atacaactgg
    46021 atggaaattt aatgagtggg aaatgaaggg tgttccagta agaattgaaa ttggaccaaa
    46081 agatatagaa aacaatcaag ctatggtatt tagaagagat actttagaaa aggattctat
    46141 gcctttagaa ggattagctg atgctgtatg tgatttattt gatgttatac acaatgatat
    46201 gtttgaaaaa gcaagaaaac atagagaaga caatacatct atagttgaaa atatggatga
    46261 gtttagaaaa gctttagaag aaaagccagg attcataaag actatgtggt gtggagatgc
    46321 agaatgtgaa gctaagatta aggaagaaac aggagcaact ataagatgct taccttttga
    46381 acaagaaaac ttaggtcaca agtgtgtgta ctgtggaaaa gaagcagata gtatggtagt
    46441 aatggcaaaa gcttattaaa ataatacatt taaataaaaa ctggggtaga aagtatttaa
    46501 tactttatcc cagttttttt attttttatg agaaataaaa tcgtgtttgt agatgtatca
    46561 taagataagt cataaatgct tatattaaaa agaatataat agagaactat ttttaataat
    46621 tacatattaa tgaaagaaaa atatgtttga tatgtaaatt ttcaataaag taaacaataa
    46681 atataattga atattaataa agagtacttt taatttttag aaaataaatg acttaaaaga
    46741 aagatttatg aaattaaaac taggattttc tgatataata aacatgtgta tttttaaata
    46801 aaaaggatat tattattaga tttgattaaa aataaacttg caaaacaatg tactagttta
    46861 atattatagt tatattgaat aaaatatcag gaggaagtaa aaatgaatgt aagagtaagg
    46921 tttgcaccaa gtccaacggg atttgtacat ataggtagtt taagaactgc tttatataac
    46981 tatttatttg caaaaaaaat gggcggagaa tatatattaa gagtggaaga tacagaccaa
    47041 agtagattag tagaaggtgc aatagagaat atgcttaatg ctatgaaatg ggctggtgtc
    47101 aaccatgatg aaggtgttgt attagatgat agtggaaaag tggtacaaaa aggagaatat
    47161 ggtccatata ttcaatctca aagattagat atataccaag aatatataaa gcaacttttg
    47221 gatagtggaa aggcttatta ctgtttctgt acaaaagaaa gactagatga agtaagagat
    47281 gctcaaagag cagcaggaga aacagctaaa tatgatggtc attgtaaaaa tctttccaaa
    47341 gaagaagtag aagcaaatat aaaagcagga ataccatatg ttataagatt aagattgcca
    47401 gaaaatcata caattaaatt tacagattta gttagaggag atatggaatt taacactaat
    47461 gacttagatg accaagtatt aatgaaaaca gatggatttc caacttatca ttttgcagta
    47521 gttgttgatg actatttgat gaaaattaca catgttataa gaggagaaga atgggtatca
    47581 tctactccaa aacatgttta tttatatgaa gcttttggat gggaagcacc tgtatttgtg
    47641 catttaccaa atatacttaa taaagaaaag aaaaaattaa gtaaaagaca aggtgatgta
    47701 gcagttgaag actttaagaa aaaaggatat ttaccagaag gattagtaaa ctatgtagca
    47761 ttagttggtt ggtctccaga agataatcaa gaattgttta caatggaaga attagaaaaa
    47821 gccttctcta tagaaagagt atctaaaagt ggtggagtat ttgatactga aaagctaaat
    47881 tgggttaatc agcattatat aaaagatggt gatgatgctt acctaacaga cttagcaata
    47941 ccatttttaa tagaagatgg atttataaca gaagaagagg ctactaataa atatgatttc
    48001 ttaaagagta tgatatcagt acttaaagag aaattacaat atgtaaaaga ggttactgag
    48061 catgcaagta tattttttgg agataaaata gaggtagaaa ctgaagaggg aagagagttc
    48121 ttaagattag aacatatacc tactttaata gatgctttga aagaaaaaat agaaaaagca
    48181 gaagtattaa atgctgagtt cgttcaagct atgcttaaag aaatacaaaa agagtacaaa
    48241 ataaaaggaa aaaatttatt tatgggctca agaataattt taacagggca aatgcatggt
    48301 ccagatttac caaaagtaat ggaagtttta ggaaaagaaa cttgcttaaa tagaatagct
    48361 tatgtaaaaa ataatatatt atagtcataa aagtccgcta atttagaagc ggactttttt
    48421 cgtgttagta tttggtgaaa atatctgctt aagaaaatga aggtatttaa ggtaataaat
    48481 ttaatatata aaaagcaaag caaaaatata aataaaatat gaataggaaa ctaataaaat
    48541 attaagcata gaagaaggga atctattatt ttagtttgat ttaattatta agggggtaat
    48601 tattatgtat agtaatattg atgatgttaa aaaggaatta aaggagctat gcttagaata
    48661 tgttacaatt ttagaaaaat taaaagatga aaaaatgatt acagaagaaa cttttgaaaa
    48721 gtgctcttct caaaaaaaga tatttttaga agaacaatag aggatagtaa tagtattatt
    48781 attatgtagt ttgaaagata gtacgaaaaa tgatagtaat actattattt attgcaattt
    48841 tcaactataa tataatatat aatgttaaga agataattta taaaaataca gtgaggtgat
    48901 gagtgtgaaa gtttataata cattgactag aacaaaagaa gaatttgttc cattagaaga
    48961 aggaaaggta aaaatgtatg tgtgtggtcc aactgtttat aactatatac acataggtaa
    49021 tgcaagacca tttataatat ttgatactct aagaaggtat ttagagtata gaggatacga
    49081 tgtaacttat gtacaaaact ttacagatgt tgatgataag attataaata gaagtcatga
    49141 ggaaggaata tctcctgaag aagttgctgc taagtatata aaagaatatt ttgtagactg
    49201 tgatgggcta ggaattaaaa gagctactgt tcatcctcag gttacagata atatacaaca
    49261 aattatagag tttataaaag aattggaaga taagggatat gcatatgcag taaatggtga
    49321 tgtatatttt gatacaaata aatttgaagg atatggaaag ctttcaggtc aaaaacaaga
    49381 agatttagaa gcaggggcta gaattgaggt taatgaccaa aaaagacatc ctatggattt
    49441 tgttctttgg aaagcaaaaa aagaaggtga gccaggatgg gatagtcctt ggggagaagg
    49501 tagaccagga tggcatatag aatgttctgt tatgtctaag agatatttag gtgagacaat
    49561 tgatatacat gcaggtggtc aggatttaac attcccacat catgaaaatg aaatagctca
    49621 aagtgaagct agaagtggaa aaacattctc aaaatactgg atgcataatg gatatataaa
    49681 tataaatgat gaaaagatga gtaaatcaaa aggtaatttc tttacagtaa gagatatatc
    49741 aaaactatat gatttagaga tagtaagatt tttcatgtta tcagcacatt atagaaatcc
    49801 agtaaacttt agtgatgaga tgttaaatca agctaaagca ggtcttgaaa ggttatataa
    49861 tactaaagaa aaattagagt ttacgttaag taatttagta gaatctcctt taacagaaaa
    49921 agaagtagaa cttgttaaag aattagatgg atttagacaa aagttcatag atgctatgga
    49981 tgatgatgtt aatacagcag atgcagtaag tgtaatattt gaattagcta agttaataaa
    50041 ttctaatgta gatgaaaatt cttctctgga gtttgctaaa aaatgcttag atgaatttaa
    50101 tgaacttaca ggagtattaa atattgtaaa taagaaaaag gatactgtat tagataaaga
    50161 cattgaagaa ttgatacaaa aaagaactga tgcaaagaaa aacaaagagt ttcaattagc
    50221 tgatgatatt agacaacaat tactagatat gggaattgta ttagaagaca caagacaagg
    50281 tgttaagtgg aaaaggatat aaaaatggaa aaaaccgaat tagttactat gtcaccacta
    50341 gttttagcat acttaggtga tacagtttat gaaacatata taagagaaca tttaattaga
    50401 cagaatacac aaaaaaaagt taatgatttg cataaattag ctataaaata tgtaaaagct
    50461 aaagctcagg caacaataat tcatgaaatt gaaattgaat taactgagga agagagtaaa
    50521 atttataaaa ggggaagaaa tcaaaagtca aatacttctc ctaagaatgc agatattata
    50581 gactataaac atgcaactgg gtttgaagcg ctagtgggat atttgtattt aaataatgaa
    50641 atagagagac ttcaatatat tatcaataaa ggaatcaaaa ttattgaaag agatatgtaa
    50701 atattaaaga gtgttgtctt aataataagt aataaggcaa cacttttttt ataactaatg
    50761 tataataaat atatagaaat tagtaatgag aaaggataaa aaattatgaa agtaaaatta
    50821 atatcacata cacctgaacc agaaaaagta atagctatgg cagctaagct atgttattca
    50881 ccagttggga cagacgaaat agaaaaagac ttaacagatg aaagtataga gaaattttta
    50941 aatatgttat taagtatagg tcatgggtca atattagaac atgcatcatt tacattttca
    51001 atagaaggta tttcaagagc ttgttcacat caaattgtta gacatcgtat agctagtttt
    51061 tcacaacaaa gtcaaagata tgttaaatta gaacaatttg agtacataat tccgccagaa
    51121 atagaaaaaa tagaaaaggc aaaagagtta tttatagact ctatgaaaaa agaccaagag
    51181 aattatgata agttagttga aatattgttt gaaaatcatt ataatgacct gataaaaaac
    51241 ggtaaaaatg agaaaacagc taaaagacaa gctgaaaaga aagcaataga agatgctaga
    51301 tacgtatttc caaatgcatg tgaaacaaaa atggtattta ctataaatgc tagaagtttg
    51361 tttaatttct ttgaacatag atgctgtgaa agagcacagt gggaaataag aaatttagct
    51421 gtggagatgt taagagaggt taaaaaggtt gctcctatat tatttaaaaa gacgggtcca
    51481 agttgtgtaa atggaagttg tccagaagga actatgacct gtggagatat agttcaagtt
    51541 agagaaaaat ttaaggcctt gtaggaggtg aatagtttgg caaatataga aggaagaaat
    51601 ccagtaatag aagcaataaa aagtgacaga gaaatagata aaatattaat tgcaaattca
    51661 gctaaagaag gttcaattaa gaaaataata ggaatggcta aagataagaa tataattatt
    51721 cagtatgttg ataaacataa gttagatgaa gtaagtacaa gtcattcgca tcaaggtgta
    51781 atagcttatg caagtgagca taagtattat gaattagatg agctaataga tttggtaaag
    51841 aataaagatg aagacccatt tttcattata ttagatgaga taacagaccc acataatttg
    51901 ggttcaataa taaggaccgc agatgcagta ggggcgcatg gagttatcat tccaaaaaga
    51961 aggtctgtac acataactcc tgtagttgcc aaagcatctg ctggagcagt agaatatatg
    52021 ccagtttgta aggtaaccaa tatagttaat acaataaaaa ggctcaagga agaagggttg
    52081 tggattgctg cagctgatat ggatggagaa actttttata aacaaaatct tactggtcct
    52141 cttggtgtag taattggaag tgaaggtttt ggaatctcta gattggttaa acaaaactgt
    52201 gactttatag taaaaatgcc aatgataggt aatgttacat ctttaaatgc atctgtagca
    52261 ggtggaatac ttttatatga gatattcaga caaagactgg gtaaaagtaa ataggtatga
    52321 aaaaaaatat aaatcattac ttaataatag atggctacaa tattataaat gcgtgggaca
    52381 atttgaaaga actggctaaa gaggacttag aagattctcg agaaaagctt attgatgata
    52441 ttatagaatt ttctgagttt atgggttata agactataat agtttttgat gcttataatg
    52501 ttaaaaattc tcgagaaaaa gttgagaaaa gaaaacacat aacaatagtt tatacaagag
    52561 aacaccaaac agcagatagt tatatagaaa aatttataac ttctttatca aagtatgatg
    52621 atgtaaaagt agccactaac gactatgcag aacagcaaat gattttagga aaaggtgcta
    52681 ctagaatgtc tgcaagagaa ctaaagttag agttagatcg ttccaagaat aaaatgaagg
    52741 aaaaaaatat cggtttgagg aaaaaaattc agcgaaattg gttggaggaa aggttagata
    52801 aagaaacatt gtcgaaactt gagaacattc gtagaaagcg ttgaaattac taggttcttt
    52861 agactataat atacctataa atttgtttta tatatggggg agatttacat gttggtagca
    52921 aaagaaaaaa gttatgagtt agtggacaat tgtcagcagg atgagtataa cattgtatta
    52981 agagcaagtg aaggggataa aatagcacta gagtacatta ttactaaata cagaaatttt
    53041 gtaaaggcaa aagcgaagtc atatttttta attggcgcag ataaagaaga tataatacaa
    53101 gaaggaatga taggccttta taaggcagtt agagattttg atggaagtaa gaccaattca
    53161 tttaaatgtt ttgcagaaat atgtataaca agacaaataa taactgctat aaaaactgca
    53221 acaagacaaa aacatatacc tttaaattca tatgtttctt tgaataaacc aatatatgat
    53281 gaagagtcag acagaacact tttagatatt atagctacaa gtatagtaac agatccagaa
    53341 gagcttataa ttagtaaaga agagttaaaa aatatagaat caaaaatgaa cgaattgtta
    53401 agtgacttgg aattagaagt actagaatta tatttaaatg gaaagtcata ccagtttata
    53461 gcggacaagc ttaaaagaga tgtaaagtca atagataacg ctttacaaag ggttaagaga
    53521 aaattagaaa aacatcttga aaacagaaat gattaatagt aaaatactta ccataagctt
    53581 attgtgagca aaattaattt atatcgaaag ataagggagg aaattcaaaa tggctaaagc
    53641 taaatacgaa agaacaaaac ctcatgttaa tatagggaca ataggacacg tagaccacgg
    53701 taaaactaca ttaacagcag caataacaaa aacattatat gacagatatc aattaggaga
    53761 agcagtagat ttcgcaaaca tagataaagc tccagaagaa agagaaagag gaatcacaat
    53821 atcaacagca cacgttgagt atgaaacacc aaatagacac tatgcacacg ttgactgccc
    53881 agggcatgct gactacgtta agaacatgat aacaggagca gcacaaatgg acggagcaat
    53941 attagtttgt tcagcaacag atggaccaat gccacaaaca agagagcata tactattatc
    54001 aagacaagtt ggagtaccat atatagtagt attcttaaat aaatgtgaca tggtagatga
    54061 tgaagagtta ttagagttag tagagatgga agtaagagat ttattaacag agtatgattt
    54121 cccaggagat gacactccaa tagtaagagg atcagcgtta atggcattag aagatccaaa
    54181 gagtgagtgg ggagataaga tagtagaatt attcgagcaa atagatgaat atataccagc
    54241 accagagaga gatacagata a
//
LOCUS       DAMKOJ010000018        53058 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.019, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000018 DAMKOJ010000000
VERSION     DAMKOJ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53058
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.019"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(73..168)
                     /locus_tag="PC592_001178"
                     /pseudo
     CDS             complement(73..168)
                     /locus_tag="PC592_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
     gene            complement(262..1206)
                     /locus_tag="PC592_001179"
     CDS             complement(262..1206)
                     /locus_tag="PC592_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HDF4055175.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVED
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFIKKYEKNEQFSFEICDTHQELIVDSDVVISTVTYTDEYLSEYKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQGKGRENDDERIISY
                     NIGLSIHDILFANKIYELCEILNCEEIELKEPKEKYWI"
     gene            complement(1226..2458)
                     /locus_tag="PC592_001180"
     CDS             complement(1226..2458)
                     /locus_tag="PC592_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF4055176.1"
                     /translation="MKRLMILGSIKYFENIVMSAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYVANELNLPCVISCNQLESVT
                     NKAVMKKYFKNNGIPTTDYCIVESLKDLEKIQELNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEVSQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEINFDEIKKYNMHLSKCVYALPIYIKPGTI
                     KKINNVDKIESLDYVTQILLLVKEGDTIGLYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            complement(2550..3545)
                     /locus_tag="PC592_001181"
     CDS             complement(2550..3545)
                     /locus_tag="PC592_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HDF4055177.1"
                     /translation="MNNIRINKFEKSCEKHWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIIYKGEEILAVVPACEIYENGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQSFNKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DIVANFRYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSIEEL
                     LDFKNNRLKDIVEFYAVYIDGIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKNALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            complement(3554..5668)
                     /locus_tag="PC592_001182"
     CDS             complement(3554..5668)
                     /locus_tag="PC592_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF4055178.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIYDILEIFKKNADVGMIGVAGVKDI
                     PVNGIWWDSDKKVGKVYDSHTGKMDIYEFSNFDECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIIPKQNKPWCMHDSGVANINNGYDEYRIRFVKEYI
                     NLDLDRENFYEFDEKKASTILKSNKHVMDCMKEELTEQLILKNYKDVLDIVSKIARFS
                     VFNHTGLYSCEKCERALIECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPEWLLKAIDDSGGEIISLDLISDDYLKRAMALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGASIADIVIDFSE
                     ASQLITLNKRGIDKSEILPILLKEKEVFSKSEIRKQYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENIYWKTLSNVTDNRVICFGTTTNIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDRFDYKNIKEVID
                     MIKRYNTSEFDRNKIKEKQSGIKHFVIDKHCIEIKNYIDKIYNEANHHKVKCDLYKND
                     EIEEYQLFVALYGYMVKNKNMS"
     gene            complement(5661..7538)
                     /locus_tag="PC592_001183"
     CDS             complement(5661..7538)
                     /locus_tag="PC592_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF4055179.1"
                     /translation="MNTPILVNEKSKDIIKDWQYTYTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKDKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNSKNLGFPKGCNQGIE
                     LANGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSVE
                     EMFIFAQKINKSNINLWKYRLKLVGFCMLIKKSVIDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCKDTFIHHFGSISFKENRNKYTDIMDINRRKFETKWGFNPEYSGIIRT
                     DLISKIDDSPETNINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYKKNFFDYIILGDVLEHLIDPWKIVNKLKQYLKKDGYLVSSIPNVMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITAISMPLSEID
                     NRFIDTMCKESCKEMRQQYESYQYIVKATKSIDTKKYSSISMVNLKYALMRIDNELDI
                     DGNLSYIFDNYNITEPCFVDDIEYLVDTFVINKVTLLNRLGVEAFNRGLGDFSINMFM
                     KVLEMDRDDIDSIYNITSVLCELEEFDIAYNLIKNSSEKVQSESDIQEILYFIEGKRY
                     E"
     gene            complement(7562..9703)
                     /locus_tag="PC592_001184"
     CDS             complement(7562..9703)
                     /locus_tag="PC592_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF4055180.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRDSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFEELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLERYESVISEYNNIEDIEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKLDLLDIFYEMEYVWIEKYLKYLLALERSFNLALYKYIISCPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLNIKNKVNSANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFRDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDVKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            complement(9796..10668)
                     /locus_tag="PC592_001185"
     CDS             complement(9796..10668)
                     /locus_tag="PC592_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HDF4055181.1"
                     /translation="MRVNTNVSALIANNQMGRNVSAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNVDGASGTDAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            complement(10769..11104)
                     /locus_tag="PC592_001186"
     CDS             complement(10769..11104)
                     /locus_tag="PC592_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDF4055182.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISSKLDERQEIINSV
                     SEIDRNDFIQLYNKMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYSLNRE
                     KVNIFNKKV"
     gene            complement(11107..12630)
                     /gene="fliD"
                     /locus_tag="PC592_001187"
     CDS             complement(11107..12630)
                     /gene="fliD"
                     /locus_tag="PC592_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDF4055183.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNIIQESKDLYDKYLSVDSPNSIVSQKAYSSTKITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FVSDAGGNKLASVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMKSFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKSLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            complement(12651..13007)
                     /locus_tag="PC592_001188"
     CDS             complement(12651..13007)
                     /locus_tag="PC592_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF4055184.1"
                     /translation="MELNLAELGKLSKEELLLMLVDATVKYTNISKDALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNKIKI"
     gene            complement(13007..13402)
                     /gene="fliS"
                     /locus_tag="PC592_001189"
     CDS             complement(13007..13402)
                     /gene="fliS"
                     /locus_tag="PC592_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF4055185.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQRAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            complement(13424..13636)
                     /gene="csrA"
                     /locus_tag="PC592_001190"
     CDS             complement(13424..13636)
                     /gene="csrA"
                     /locus_tag="PC592_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003373164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDF4055186.1"
                     /translation="MLVISRKKDEAVLIGENIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNINILKSLK"
     gene            complement(13630..14022)
                     /locus_tag="PC592_001191"
     CDS             complement(13630..14022)
                     /locus_tag="PC592_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HDF4055187.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDSLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVMLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            complement(14039..14971)
                     /gene="flgL"
                     /locus_tag="PC592_001192"
     CDS             complement(14039..14971)
                     /gene="flgL"
                     /locus_tag="PC592_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDF4055188.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMEIYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKIKEIANALNATHEGKYIFSGSNTGIPPVECVDNADGSVSLKFN
                     SSIDLNKLKDSLSMDVAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGEMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKEILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFSVSILDYI"
     gene            complement(14990..16300)
                     /gene="flgK"
                     /locus_tag="PC592_001193"
     CDS             complement(14990..16300)
                     /gene="flgK"
                     /locus_tag="PC592_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDF4055189.1"
                     /translation="MAGLFSILNTANSGMNSHQKAIQTISHNISNLDTEGYSRQRTEF
                     ATNSPMYMPSLSNSIGRGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKGDIDSNIDTEIKQINEMLKSLEDLNKSIDIISGSGSMPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNADGTWKTGVSGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVRDFFVTSNVDGEDIIKVNPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAELVGLDSKKVNQDEVNQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            complement(16318..16734)
                     /locus_tag="PC592_001194"
     CDS             complement(16318..16734)
                     /locus_tag="PC592_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDF4055190.1"
                     /translation="MITDLKVIMYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSKDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPVDKQTTTYNSYGNIRK"
     gene            complement(16739..17014)
                     /gene="flgM"
                     /locus_tag="PC592_001195"
     CDS             complement(16739..17014)
                     /gene="flgM"
                     /locus_tag="PC592_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDF4055191.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGVKKVEDVKKINKTDKIELSKFAK
                     EMASVSNMSDESIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            complement(17166..17480)
                     /locus_tag="PC592_001196"
     CDS             complement(17166..17480)
                     /locus_tag="PC592_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF4055192.1"
                     /translation="MNSKKEDIYELNFGQLIEEQSGIIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLNKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     IN"
     gene            complement(17504..17932)
                     /locus_tag="PC592_001197"
     CDS             complement(17504..17932)
                     /locus_tag="PC592_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HDF4055193.1"
                     /translation="MGINIDKLKISPSINIEVKKLKENNKFSDRLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            complement(17941..18609)
                     /locus_tag="PC592_001198"
     CDS             complement(17941..18609)
                     /locus_tag="PC592_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF4055194.1"
                     /translation="MNEISSLINILALTQLSGSNNTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNGYNISSNSENLFNELENVVNNTTSRFIDVDTKDKNVKLRIENAVEQA
                     SKKYNVDANLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            complement(18647..19630)
                     /gene="rfbB"
                     /locus_tag="PC592_001199"
     CDS             complement(18647..19630)
                     /gene="rfbB"
                     /locus_tag="PC592_001199"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDF4055195.1"
                     /translation="MKKILITGGAGFIGSNFVHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVRGDISNREQMYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSPINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLKVVKIILNLLGKSEDLISYVND
                     RPGHDLRYAIDASKIQNELGWKAKYDFDFGIKETVKWYIENESWWKSVLSV"
     gene            complement(19668..20225)
                     /gene="rfbC"
                     /locus_tag="PC592_001200"
     CDS             complement(19668..20225)
                     /gene="rfbC"
                     /locus_tag="PC592_001200"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDF4055196.1"
                     /translation="MGKINVIKTKIEGLYIVEPSVFCDERGYFMESYNKRDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVRYPQGKLVRVTEGEVFDVAVDLRKDSKTFGEWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFNYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICIRR"
     gene            complement(20274..21143)
                     /gene="rfbA"
                     /locus_tag="PC592_001201"
     CDS             complement(20274..21143)
                     /gene="rfbA"
                     /locus_tag="PC592_001201"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDF4055197.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLKITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLEKAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYKKGYISRAQLMELAKPLIKTE
                     YGQYLLKLASEDM"
     gene            complement(21252..22124)
                     /gene="rfbD"
                     /locus_tag="PC592_001202"
     CDS             complement(21252..22124)
                     /gene="rfbD"
                     /locus_tag="PC592_001202"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDF4055198.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSMSQPKYAILATTRNDFDI
                     YNQTNVDNFILNNKPDVVVNCAAYTKVDACEDNIETAYKVNALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDSKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLTKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFELKNIDIKVNPIKSNEFKCKAQRPLYSVLDNFMLKLIGLNSFRNWEE
                     SIEEYLERYDMNEE"
     gene            complement(22328..27409)
                     /locus_tag="PC592_001203"
                     /pseudo
     CDS             complement(22328..27409)
                     /locus_tag="PC592_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013725947.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
     gene            complement(27420..28952)
                     /gene="purH"
                     /locus_tag="PC592_001204"
     CDS             complement(27420..28952)
                     /gene="purH"
                     /locus_tag="PC592_001204"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDF4055199.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKAKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            complement(28945..29538)
                     /locus_tag="PC592_001205"
     CDS             complement(28945..29538)
                     /locus_tag="PC592_001205"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDF4055200.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQDAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            complement(29532..30608)
                     /locus_tag="PC592_001206"
     CDS             complement(29532..30608)
                     /locus_tag="PC592_001206"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDF4055201.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHEIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVNERELHKSFNMGIGLVLIVDKANADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            complement(30602..31969)
                     /gene="purF"
                     /locus_tag="PC592_001207"
     CDS             complement(30602..31969)
                     /gene="purF"
                     /locus_tag="PC592_001207"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDF4055202.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKESELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            complement(31981..32679)
                     /locus_tag="PC592_001208"
     CDS             complement(31981..32679)
                     /locus_tag="PC592_001208"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF4055203.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            complement(32685..33161)
                     /gene="purE"
                     /locus_tag="PC592_001209"
     CDS             complement(32685..33161)
                     /gene="purE"
                     /locus_tag="PC592_001209"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDF4055204.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     STFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            33611..34123
                     /locus_tag="PC592_001210"
     CDS             33611..34123
                     /locus_tag="PC592_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4055205.1"
                     /translation="MLEVIKNRRSIRAYINKSVEEEKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKKLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWVGVFPKNKVVNKVRQTLDLPVKLVPYSLISIGYSEEKNEFIDRFDEN
                     KIHRNIYKNR"
     gene            34673..34888
                     /locus_tag="PC592_001211"
     CDS             34673..34888
                     /locus_tag="PC592_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055206.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            34894..35187
                     /locus_tag="PC592_001212"
     CDS             34894..35187
                     /locus_tag="PC592_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDF4055207.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWFKPYDKPIQQLTCSYKESQNVID"
     gene            complement(35369..36082)
                     /locus_tag="PC592_001213"
     CDS             complement(35369..36082)
                     /locus_tag="PC592_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF4055208.1"
                     /translation="MINLIFDVDDTLYNQLTPFYIAYNKVFSSIKNISIEDLYMSSRK
                     YSDEVFHMTENGEMAIKEMHIYRIMKAFEELGTSITEKDAQSFQDEYIYQQSQITLIP
                     EVEWVLNFSKERNINLGIITNGPSTHQRMKLKQLNIENWVDKNNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYMGDSYRNDVLGAKKAGWKSIWLNHRRHEVEGVFYKPDFL
                     ILEHKDLMSLFIKICSKKC"
     gene            complement(36170..37435)
                     /locus_tag="PC592_001214"
     CDS             complement(36170..37435)
                     /locus_tag="PC592_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HDF4055209.1"
                     /translation="MKKLPIKTVVQRLLELQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKIADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPEIGYEVGTEETNGGLTSTETYETFITRLKVELDKRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SSIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVDKTSNIRHVLLVNAIECGRWRK
                     WVIGEQKNLTTEDIFKNEVLSNEILDIAGHYTFNNDDVKKEIEVLYANLSKNNIDGQR
                     FVIDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            complement(37539..37847)
                     /locus_tag="PC592_001215"
     CDS             complement(37539..37847)
                     /locus_tag="PC592_001215"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDF4055210.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKEIEEATCVILTNDVEIRNMERFKGKKVVRMSVSDIIKKSDALIKKIKDTFQ
                     "
     gene            complement(37918..38973)
                     /locus_tag="PC592_001216"
     CDS             complement(37918..38973)
                     /locus_tag="PC592_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDF4055211.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMVGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAILMKLVKKDVKEDE
                     EIEEDLDDSIELIFEEL"
     gene            complement(38975..39427)
                     /locus_tag="PC592_001217"
     CDS             complement(38975..39427)
                     /locus_tag="PC592_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055212.1"
                     /translation="MSKLVNVKCSFKIHANSKEEAIISLVDVVSKEGYLRDKNQFLED
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEGED"
     gene            complement(39424..41454)
                     /locus_tag="PC592_001218"
     CDS             complement(39424..41454)
                     /locus_tag="PC592_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055213.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKPVIQKMNKGVLIIPDNFQVVCINNNEYVFSLTERVSIMKIISMFKIENLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKAFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGISLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESVSLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLNQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLINDYQINIVDSIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     VICQELGYSDERALSRQLNLGDLIGIDTIRIIDEDMKWEDAVKISSNILANCDFVSSQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVRIIF
                     CLASKDKKEQIPAIINLTKMVYKTNFISMLESAKTKEEAEGLIHKYEKEVTV"
     gene            complement(41719..43947)
                     /locus_tag="PC592_001219"
     CDS             complement(41719..43947)
                     /locus_tag="PC592_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4055214.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISSKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDIGI
                     IDLEGKAEFLSGKKFDLKNTDSYKKGIEGKEYSEVIESMGFVFYSVPIFNDNHEVSSI
                     LIGVSNKESMDEILNIDNFNGEGTIEIINSQGRPLFIGKNTELIKDLGHKYKSSGDEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYYPITKGLNDWHFVLIVPEDAVLGELNK
                     LNSFTIIMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSILVKP
                     LILESPDSTYMMVAINIKDFKLINDCFGSKKGNLTLKHLYNVLYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADINYFNKNRENPYFLRISAGIYTIENHNEDLIT
                     IQDHANTARKSFNKAHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKLICNKYNVPTYLIDLELTESIFLENPEAVD
                     IIDDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFEDFAYENNKIK
                     NI"
     gene            44596..48024
                     /gene="uvrA"
                     /locus_tag="PC592_001220"
     CDS             44596..48024
                     /gene="uvrA"
                     /locus_tag="PC592_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF4055215.1"
                     /translation="MIINNYQNQSIITNPKKFENEYQYLPDTPIELLKVVQNLIIHGD
                     QGKLYGISFNKQQSDEELLRTVPQMLKRIFEINSNSLTIPRTPKQRLVGMCRDYSLLL
                     VSFLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTATKRWIKIDAQIDDIQKNYF
                     QINFDAHDVRRIDGFLTGSEAWIKCRQEHTHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNKKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELANPLELEKKFKFTKAINKPIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNKITVITGVSGSGKSSLAFDTIYEEGKRRYFENLGNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGNQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKTPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESRGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELTNQLQQKELSLVNDILTELKIRVSYLLK
                     VGLSYLSTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPNAGIKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPNKNYTELTGFDAIDDFILMDQTAIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYIADQWVTCNKC
                     QGKRYKKEILSIQYKGKAIADILDMEVAEAKTFFSDCSDIYRKLYLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGMNGGEIVASGTPDEIKVNPNSITGHFI"
     gene            48209..49042
                     /locus_tag="PC592_001221"
     CDS             48209..49042
                     /locus_tag="PC592_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4055216.1"
                     /translation="MSWKHIKIPNGDTMIFCNSFITSKLSMNIIVTHTPIVTTLEMQK
                     AYEPFTKYNVNIFAFDFSGTGKSDGYEKDFSRNSIIKDLDSIITYIEKNYSSNIHLYG
                     NTGIGGMFAQYYACSDNKLKSFAQFACVDYKNTTGVGYPYLTVKLLNLFFKFLPNFHI
                     TVKPPKYKGYNEVYDNEFYKIFEEKNPHIWKNSTKIINTMLECFIAEDSKIKDGVNIP
                     TLVFKTLHDRYFKTQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVEN
                     Q"
     gene            complement(49171..49737)
                     /locus_tag="PC592_001222"
     CDS             complement(49171..49737)
                     /locus_tag="PC592_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF4055217.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(49734..50297)
                     /locus_tag="PC592_001223"
     CDS             complement(49734..50297)
                     /locus_tag="PC592_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF4055218.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKHFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCCVCVMQVFYKKRKNK"
     gene            50417..51292
                     /locus_tag="PC592_001224"
     CDS             50417..51292
                     /locus_tag="PC592_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4055219.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETSLFDRLPRGVCLTRCGISLLEEARSILTACRNLDKRISRLEECTPINIVSSITIAS
                     FLLPPILSRLKNLFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSEQTLSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPIWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLLHKKLRLIELDGIDMENKMLAILHKDKNI
                     TQPLKIILDNISNVL"
     gene            complement(51440..52627)
                     /locus_tag="PC592_001225"
                     /pseudo
     CDS             complement(51440..52627)
                     /locus_tag="PC592_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
     gene            complement(52745..>53058)
                     /locus_tag="PC592_001226"
     CDS             complement(52745..>53058)
                     /locus_tag="PC592_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF4055220.1"
                     /translation="DLQVKNMIRNHKLSRLISDVSWSEFIRQLEYKANWYDRQIVKVG
                     KFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLITIQN
                     K"
BASE COUNT        17156 a         9379 c         5684 g        20839 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcataa ctaaagtcac aagtgtgcgt
       61 agctattttt taatcaaaag gtattacttt atttgattct aatgcaacta aatttcctat
      121 atattcattt ccaatagata cgaacttaat taaattatat ttatccataa atttatctat
      181 cctattcata ctaattttct aacaatatat tacttcatat tcatatttaa aataaattac
      241 cataaatatg aatgaaataa actatatcca atatttttct tttggttctt ttaattctat
      301 ctcttcacaa tttagtattt cacacaattc gtaaatttta tttgcaaata atatatcatg
      361 tattgacaaa cctatattgt aagatattat tctctcatca tcattttctc ttcctttacc
      421 ttgtttactt aaaacatcat aaaattcaca agaatactta tatctatcta tattttctag
      481 gtgtttcaaa tgattataat catctaaata taccttatca aatagataat caacatttcc
      541 aaatcccata acatgtacag gtaataataa agcacctttt ttaaaccatt tatattctga
      601 taaatattca tctgtatatg tcacagtaga aataactaca tctgaatcta caataagctc
      661 ttgatgtgta tcacatattt caaaactaaa ttgttcattt ttttcatact tttttataaa
      721 tgactctgct tggtctttat atttaagtaa ctttatattt atatttttat ctttaagagt
      781 atacgaaagc atattcatta tagcagaagc agttacacct aaacccataa tagcaatagt
      841 attaaaatct tttttagcaa atgtatcaat agccaaggca gcaacagcag cagtcctaaa
      901 agctgtaata taattaccat ccaaaatagc ctttaattta gcatcttcca tattatatag
      961 aaatatctct gaatttaaac ttggatttct ccctggcaac cttgtaacca tttttattcc
     1021 accaatcata tgattatgat ttagggaagg cattacattg taaaatacat gtccatcttc
     1081 taccatgctt atttttggtg gtaattgaca atcttttttt gttaaaaagg attcttttat
     1141 ccactcatac ccttgtttct gagaaatgtt taatgacata atttgttcat gagttatcag
     1201 cttcatatct atcatactcc cttatttaaa aattttctat catattctca ttattttcat
     1261 caagtatttc tatcatttca tgaatacatt tcttctttat atttgcatca aatatattat
     1321 ttgctattcc ataaactctt ccacaatcct gtctctcatc ttcatataat cctattgtat
     1381 ctccttcttt tactagtaat agaatttgag tgacataatc taagctttct attttatcta
     1441 cattatttat cttttttatt gtcccaggtt ttatgtatat tggtaatgca tatacacatt
     1501 ttgatagatg catattatat ttctttattt catcaaaatt tatttcatta ttcacactaa
     1561 agtttgcaaa taagcttcct atgtctaaat ctgttatttg agaaatagcc atatagtcac
     1621 aacctccagg taatcttggc attacttcag atacctttat tccatatgct cccactaaca
     1681 tttgtacata aagaggtcca ttttttatat caaaagcctg tgttatattt tgatatatag
     1741 attttatttc ttcctcatat tgaaaacagt actttgatgg ataaattaat ctatctggtt
     1801 ttccagctct tcctgtatgt atatttacaa gctctctatc tccaatataa aatacatgag
     1861 actctccatt atgaacccaa gctagacctt gtatttcctc actttcataa aattcctcaa
     1921 ttatgacttg tccatcttgt gaaacttcct tagaatattc aaacttttct attaattctt
     1981 ctatatttga tacaaaatat acaccccttg aaccatagcc atcaacaggt tttattacga
     2041 gtggaaaatt taattcttgt attttttcta aatcttttag actttcaaca atacaataat
     2101 cagttgtagg tattccattg tttttaaaat attttttcat aacagcctta ttggttacag
     2161 attcaagttg attgcaagaa attacacatg gtaaatttag ttcatttgca acataaacat
     2221 atggtttcat taaagaatct gtaaatccag ttaaaattcc atctatcttt ttatctatag
     2281 ctatactttt tattttatca aaatcaaata catcaacatc tattgcttca tcacaaatct
     2341 ttttagcagg agtatcaatt ctattatcac aaacaattgt gtatattcct tcttttttag
     2401 ctgacataac aatattctca aaatacttaa ttgagcctaa aatcattaat cttttcatat
     2461 ataaaccttc tttataaact aattattttt atctaagatt agagtactat atatttacta
     2521 tactctaaaa actctctaaa acattattat cacttattta tatttttata gtacgttctg
     2581 ttgcaaattg cacttgagcc aaaaccttct ttaaatgtag ctaaaccctc gtctaagtat
     2641 ttacctctat ttagagtgct aattccaaaa gaaagatact taaaatttct ctctaaagca
     2701 ttttttatta gattataata taaaaatatc attggataat atttattata tgtcgaattt
     2761 gatgctagat attgagtatg ataaactctt tcttgaaagt taaataccat actcccacaa
     2821 atcataatgc catcaatata tactgcataa aattctacaa tatcttttaa cctattattt
     2881 ttaaagtcca gaagttcttc tattgaatgt attactttag ctcctttact atctaaacaa
     2941 ttagaaagta aattaaaaaa acaaactata tcttcatcac tatacagtct tttaaaggta
     3001 agattgttct tcaaagaata tttaaaatct cttcttttac tatatctaaa attagctact
     3061 atatcttctt tatacttact taattctaaa aacatactta attcatcata aaacatgtaa
     3121 ttattcttaa atagaaaata ttctagtaat gaagtatcct ccttacaaaa tattcttgat
     3181 gtatttttta aatatacttt attgaaactt tgttcttgta aatatatttc taacttattt
     3241 gtaatagcat ttacatgcct aatatcatta aaaccacttc ttattataat acctccaaaa
     3301 gtgcttccta aatgagaaaa aaatattctt tcaccatttt cataaatttc acatgcaggt
     3361 acgactgcta gtatttcttc acctttatat attattaatg agtggtcagt aaattttccc
     3421 tcttcatgat aattaaggaa atttctagtt tgcagaaatg taccatttat agatttattt
     3481 tctacaaaat aatcccagtg tttttcacag cttttttcaa atttattgat acgaatattg
     3541 ttcattttac cacctatgac atgtttttat tttttaccat ataaccatat aatgctacaa
     3601 aaagctgata ttcttcgatt tcatcatttt tatataaatc acacttaact ttatgatggt
     3661 tagcttcatt atatattttg tctatatagt tttttatttc aatacagtgt ttgtctataa
     3721 caaaatgttt tattcctgat tgtttttctt ttatcttatt cctgtcaaat tcactagtat
     3781 tgtacctttt tatcatgtct ataacctctt ttatattctt ataatcaaac ctatctataa
     3841 aattccacat attcgtaaaa attggtgaaa cttcattttt aaacttaaca ggaattaaat
     3901 catataaaat tgcatctaat tttgaagtgt gacttcctac catgaaagac tctagatata
     3961 tatccgaaat cttataaaaa tcgtctatat ttgttgtcgt cccaaaacat ataactctat
     4021 tatctgtaac gttacttaga gttttccaat agatattctc tgtatcaact cctacaacaa
     4081 taataattgt attatccgta ttttcaatca atgttttagc aattttaaag taattaatat
     4141 catttacact attgtatttt ctttcactag caatagtcaa tattattgtc acatcatcct
     4201 ccaaattata ttgttttcta atttcagatt ttgaaaatac ttctttttct tttaatagaa
     4261 ttggtaatat ttcagattta tctatacctc ttttattcaa tgtaattagt tgactagctt
     4321 cactaaagtc aataacaata tccgcaatac ttgcccctaa ccaaaaagtg ctgtcataat
     4381 gattaacatg taaaataggt attttcccat caactccaaa agcaacaaca ggtattgtat
     4441 cccacatatg aacatataaa ataactatat cagcccagtc ataagctatt tttctcaaag
     4501 ccatagctct ttttaaataa tcatctgaaa ttaaatctaa agatataatt tcgccaccac
     4561 tatcatctat tgcttttaat aaccattctg ggagtgtgtc tgattgccat gtagttacaa
     4621 ctgaatgaac agagtctttg tcaatctcaa tccagttttt aactagtctt gtatgacctc
     4681 ctgttgaata tccttcactt aaaacatgta atacttttct tctttttaaa tctttttttg
     4741 taaataattt cgtattttct atttctggta aattatttgc acattctatt aatgctctct
     4801 cgcatttttc acaagaatac agtccagtat gattaaaaac agaaaaacga gcaattttag
     4861 aaacaatatc taaaacatcc ttataattct ttaatattaa ttgttctgta agttcctctt
     4921 tcatacaatc cattacatgc ttattactct taagtatggt acttgctttc ttctcatcaa
     4981 attcataaaa attctctcta tctaaatcaa gatttatgta ctcttttaca aatcttatcc
     5041 tatattcatc atagccatta tttatatttg ctactccaga atcatgcata caccaaggct
     5101 tattctgttt tggtataata actttgtatt tattttgtct aaactccata ctctgtgaca
     5161 aatcataaaa atgccatcca tcaaacttat cctctctcca gaatacatca tattgagtaa
     5221 tcataatcaa tccatctata gccataactt cattaaaaca ttcatcaaag ttactaaatt
     5281 cataaatatc catcttacct gtatgactat catatacttt ccctactttt ttatcagaat
     5341 cccaccaaat tccattcaca ggtatatcct ttactccagc tacaccaatc attcctacat
     5401 ctgcattttt tttaaatatc tctaaaatat catatatgaa atttttatta attataaaag
     5461 tatcttgatg taaatatacc ttatacttag aatctgtttc tctcatagct ttattataag
     5521 cagaggcaat agaatcggct cctcttaaag ctactgtttc tatactaaag tttttaggaa
     5581 tatctaggct atttatatat acaagacatt cttcataaag tctttcatca tttacacagg
     5641 ttataaaaca tatcttatca ttattcatat ctcttcccct caataaaata aagtatctct
     5701 tgtatgtcac tttcactctg tactttttcg ctactatttt taattaaatt ataagcaata
     5761 tcaaattctt ctaattcaca taatacactt gttatattat atattgagtc aatatcatct
     5821 ctatccatct ctaatacttt cataaacatg tttatactaa aatctcctag acctctgtta
     5881 aatgcctcaa ctcctaatct gtttaataga gttactttat ttatcacaaa tgtatcaact
     5941 aaatattcaa tatcatcaac aaaacatggt tcagttatat tataattatc aaatatataa
     6001 cttaaattac catctatatc caattcatta tcaattctca ttaaagcgta ttttaaatta
     6061 accatactaa tactagaata ttttttggta tctatgcttt tagtggcttt cactatatat
     6121 tgataagatt catactgttg tctcatttct ttacagcttt ccttacacat tgtatcaata
     6181 aatctattat cgatttccga aagcggcata ctaatagctg taatactatt tattatgtaa
     6241 ttactatcat taaacatttt cgttatctca tttaatgtaa aaaaccttaa atgggtcttg
     6301 tccagaatcc ctgaatcttc atatgtaaaa ttacctaaca caagatttct taaaacagaa
     6361 acatgcataa catttggtat actagatacc aaataaccat ccttttttag atattgtttc
     6421 aatttattga ctatcttcca tgggtcaatt aaatgttcaa gtacatctcc caatattata
     6481 taatcaaaaa aatttttttt ataatccaat tttacttttt ctatatctgc tattagcacg
     6541 tctgcactat attttgcaag tttaccagct gactcactaa tttctattcc atatattgat
     6601 gcatttttat atatattttt tatttctaaa agagtagctc ctataccaca tccaatttct
     6661 aaaacattga tatttgtctc tggactatca tctattttag aaatcaaatc tgttcttata
     6721 attccactat attctggatt aaatccccac ttagtctcaa attttcttct attaatgtcc
     6781 attatatctg tatatttatt gcgattttct ttaaaagata tacttccaaa atggtgtata
     6841 aaagtgtctt tgcataataa taacttatat cctgactcta tcattctaaa agataaatca
     6901 tcatcttcaa aatttccagg cgtgaatagt tcatctaaaa ctcctacatt atctattaca
     6961 gattttttta ttaacataca aaaaccaact aacttcaatc tatatttcca tagattaata
     7021 ttagatttat ttattttttg tgcaaatata aacatctctt caactgattt gtagtcaaca
     7081 tcaatctgtt gatagtatga acatgcattt gttattggac ctacagctcc tatattatct
     7141 tgtgaccata aagccttatt caaattataa agccaatttg gagtaactat tacatcatta
     7201 tttaacaaca atatattttc accattagcc aactcaatac cttgattgca accttttgga
     7261 aatcctaagt tcttgctatt atacacagat tttatatcag attgtccctt taaccactca
     7321 actgttccgt cagaagagtt attgtcaatt attattattt catatttatc ctttggggta
     7381 aatttcctaa tactttcaat gcataactta gtatattcta tttgattgta tgtcaatatt
     7441 attatgcttg taaattttat atcttcattt gtatatgtat attgccaatc ttttattata
     7501 tctttagatt tttcattaac caatattggt gtattcattc ttcaattctc ccatttttga
     7561 cttatcttaa actttttaaa tattctatat tatatatagt gtcttcattt tctacatcta
     7621 atgataatgc cttttttaac ataaagtcag ctttgtcaag cttattttca aacatatata
     7681 aaattccctt tatgtttaaa atctttacat catccacaaa tgtttttgag tagtcatcta
     7741 ccaataattt cgcatcattt attttgccag tttcaatcat attttctata ctaataataa
     7801 aactatcttt taaatcccta aactcttcac tttcttttat attttcttct aattcaccta
     7861 taagtatttt tattatttta ttataaaaag gatactcatt tagtaatttc ctcatactat
     7921 gtatatactc taatttttca ttagcactat ttactttatt tttaatgtta agtagatgct
     7981 taaattctat agtgaactta tctaaatcat tacaaacaaa ttttattaat tcaaagtcac
     8041 ttaaattgct atatatgtat cttatgtact tataagaata cattatataa agataaaaaa
     8101 tttccttata tttttcatca cttaagctta tactttctaa aactacttta gatatagctt
     8161 tatatactct tatcttttcc atatctgatg tatttggaca actaattatg tacttatata
     8221 gcgctaaatt aaaacttctt tctaatgcta aaagatactt tagatatttc tctatccaga
     8281 catattccat ttcataaaaa atatctagta aatcaagctt ctcttcaaaa gctattttta
     8341 taatatatgc ataaattatt tccttttctt cattgagtat ttctttacat ttatctatag
     8401 atacacattt atttatcctt atctgattta aaatgccata attaccttca atgtcacaaa
     8461 gaattttata tacatactct ttttcatctt ctttaatatt atttataact tcttctatat
     8521 ttctataaaa actatttttt tcaatttttg aatttgaaac ttctttataa tagtttttta
     8581 tatcttcaaa tctattcaat ttatataggg acataaataa actaaagtac acattctttt
     8641 tcttttctat atcttcaatg ttattatact ctgaaattac agactcatat ctttcaagct
     8701 tataataaat ctttataagt gtaataatag cctcatccct aagccctaca gtatcagtgt
     8761 ctgaaaacaa actatttgct tgtgtactta tttcataatt atctaacaaa taaatgtatc
     8821 tcttatacga atctatacta ttttcatact tccctaaatc tacttgtgct tgtgcaatat
     8881 aataatatat atcaatatta ttcatgtctt tcttaatata ctttagacac aatttttcac
     8941 acttcttatg ttttcctaaa tataaatatg tttttacaag gcttgttatc aagtaaccag
     9001 gtgccgattc tagtttagaa tataattcat aagacttctc aagataatat aaagcctcct
     9061 gatattttcc taatataata aaattttttc ctaattgata atttgtatat ggagaattat
     9121 cattctcttt taactcttca aataatagtt tttcatttct ttttacttta tttaatctta
     9181 tttcttcatc ttcaaacaaa tatccataat gttcaaagtc agcaacatta ttaaatatag
     9241 ggtttttgta tattggttgt tcatgtactt taccatggta tctaaaatca acgtttttaa
     9301 aaagtctaag cactgaacaa tatccatata attttttatc atatgagtaa agatttttta
     9361 attgtattga agcagaatta aattttttat caagaccatc tttaaaaaat ttcacaatag
     9421 ttgaagaatc aatcagtatt tcgtctgcat ctaatataag taaccattcg cccttggcat
     9481 aggatattga tatatttctc atactagaaa aatcattatt ccaattatga aaatacactt
     9541 tttctgtgta ctttttagat atttttatag tatcatctgt agaacctgta tcaactatta
     9601 taagttcact ctctatagaa tctcttaatg tggttaatga ttttaaagtt ttttcaagta
     9661 ttttttcttc atttttaaca atcataacta tactaagcaa catatatatt ttcctttcaa
     9721 aagtatattt ttaaaaaaag aaaggagtaa agcaaagcct taccctttct tctatatcca
     9781 atatacaaaa ttattttatc ctaataattg taaaactcct tgtggttgct gattagcttg
     9841 agcaagcatt gactgtgatg cttgaactaa tatattcatt ttagataagt taaccatttc
     9901 tgaagcaaca tctgtatctc ttattcttga ttcagctgct gtaacatttt ctatagtatt
     9961 atttaagttg ttttgagttg attctagtct attttgttgt gcccctaatt ttgctcttga
    10021 tgtatttaat tctttaagag ctacatctaa actagatacc atttgtttgg ctgcatctgt
    10081 tccagaagct ccatctacat ttaagcttgc tattgtagaa cttgttatac ctgccttact
    10141 cattatgctt gaagtattta ctagcgcaac ttttatttca ttgttgttgt tagttgttcc
    10201 tgcaacattt gttccaaaat tagctccaac ttgtaatctt atttctgtag aacttccatc
    10261 aagtaatttc ttaccattaa actcaattga gcttgatatt ctttcaactt catcctttaa
    10321 ttgtaacaac tcatcagcta tcttttgtct ctcttcagca gtattagttt catttgaaga
    10381 ttgtactgat aaagttctca ttctttgtag tatattacca gtttcttcta atgcaccttc
    10441 tgctgtttgt acaacagata taccatcttg aacgtttctt cctgcttggt ctaaaccttt
    10501 tatttgagct ctcattttct ctgatatagc aagccccgca gcatcgtccg cagctctctt
    10561 aattctaaca ccagaagaca gcttctccat agacttactt tgtgcactta cgtttcttcc
    10621 catttggtta tttgctatca aagcacttac atttgtatta actctcatta ttttaccctc
    10681 cttagtatag ttgacatcct tgtcatttct actcttaact tttttattaa ttcttcattt
    10741 atataatcgg acaagactat atataacttt atactttttt attaaaaata tttacttttt
    10801 ctctatttaa gctataatac attgtgttca cttgtttagt aagcttatac tcatgtaatt
    10861 ctttttttac ttctaataat tgtccttgta aaatatctct tattctacta tcaatttcaa
    10921 ttaattccat tttattataa agctgtataa aatcatttct atcaatttca cttacactgt
    10981 ttataatctc ttgtctttca tctaatttgc tacttatctt tatatattct tccttttcaa
    11041 tcaaatttat aatttgtaaa gagatatctt tatataaatt taatttttct tttaatttat
    11101 ccataattaa ttaccttgtg cttgtgagaa ataattcatt tgggaagaat actgattcaa
    11161 caaagattct aaagctgaat atttagcata aagtcttttc tctttatcat tcattttttc
    11221 aactaaccta cttatatttc tttcttgctc tgcaatttgt tttgaataaa cattttcact
    11281 agcagaagca gttttttcta tacctgcttt tttaggaagt ttagaagttg aacttccaga
    11341 atattcatat acaatatctt ttagcttttc aaacattccc ttatcatcat aattcgaaga
    11401 atagcctgct agtgatttgt ataccttatc actatcatct ataagagcct ttgaaaaagt
    11461 atctgcatta aacgatattt gacccttttt attgtaattt tcgctttcat tgatacctag
    11521 ttttcttaat gcaataatat tttttccatc tccaaaaaat gcagattgaa tatcttcaac
    11581 aaaacctctt agctcatcat catttctaag tataccttct ttagctttct tttcccattt
    11641 ttctatttct tcagttgtca tatcttcttt ttgggcatct gtaagagggg gataatcctt
    11701 tggtttttta gtagtaacta aaccatatac cttgtccata agtttattat aatcatccac
    11761 aaatgacttc atatttttaa cagcttcttc agtatcagtt acagaagtta actttgcagt
    11821 tccttttgaa tttacattat agtcaatatt atctatatta aacgaattct gttctttact
    11881 tatatgagtt actcttccat gttcatcagt tacatcagct tctagatttt ttccatatac
    11941 acttgccaat ttgtttccac cagcatcact tacaaatgtg ataccattat cattagcaat
    12001 ttgctgagct aaattgtcat ttccaattac tcttaaatta atatctgatg atgaaccagt
    12061 ctgttttctt gaaataatca attcacctgt catctcacta taagaagcct ttatatcatt
    12121 atctgcacaa agcgagttta tcttacttac aatagtgctt gtagtatctt gttcagagat
    12181 tggtatattt acatctccta tagttaaaga actagctcca ctagcatttg gaggaaactg
    12241 ttgaacaata ggttcacttg aatttaattt gatagtaaat tttgctggtt cagccatttg
    12301 agaaactgca aattgataat ttattttttc tgcaccagct gagccttttg ctactataat
    12361 actttcatca gaactagtta tttttgtaga agagtatgct ttttgactta ctatactatt
    12421 aggagaatct acacttagat atttatcata aagatctttt gattcttgta taatatttct
    12481 atatatttct tgcttccatt taacgatttg ttgctcttgt tttgctttat caactttttc
    12541 cttatctcta atcatactag cttctattat gccttccata tcaaaatttc ctgaaagacc
    12601 tgtaactctt ataggactta tacttgacat ccctctatcc ctccatccaa ttatattttt
    12661 attttattgt aaacttcatg ccatgtatct ctaatttgtt ttactattgg caatatatca
    12721 tcaattattt taatatcttt attttcatca gctattgcta attcagattt tataaattca
    12781 taaactttat acatatcctt tgcccattgc cctgcatctt ggtctaatgt agtcattagt
    12841 tctgtaaata tattttgaac tcttacaagt tcattatgtg cttttaaata atcgttattt
    12901 aaaagagcat ctttggatat gttagtatat ttgactgtag catctacaag catcaatagt
    12961 aattcttctt ttgataactt acctaattca gctaaattta attccattat ttatacctac
    13021 ttctttcctc tttacttttt ttatcagctt catgccatgt atctttaatt tgttctatta
    13081 caggcaacac attatctatt atctgaatgt cttttctaat attagctctt gaaagttcat
    13141 atcttacaaa atcataaact ttatacatat cctttgccca ttgccctgca ttttggtcta
    13201 atgtaaccat tagttctgta aatatatcct gaactcttac aagctctcta tgtgctctct
    13261 gcgtattttt atctaagata gctgctctgg ctattttggt atattttact gctccatcaa
    13321 caagcataag caataattgt tcctttgatg ccataaaaac agcattttgt ttataagaat
    13381 tataaggatt ttctccatac atatattact tcctccaagc ttattatttt aatgacttta
    13441 aaatatttat atttttattt gtagctttaa tattctcact ctttactttt tcgtatattt
    13501 cttttcttaa tatgcttata ttgttaggtg ctgatatagc tagtttcaca ttgtttccat
    13561 ctacccctac aatttttact tctatgtttt ctcctataag tactgcttca tctttttttc
    13621 ttgaaattac tagcatccac tatcacctct caataatgga tgccttattg aatatttatc
    13681 atcttgtaaa attatttgca ttccaaaatt agtttttata tttatcacta taggagcttt
    13741 catgtttaca gttgattctt caaacgtctg accaagagta attatattaa atagcataac
    13801 atcctttgga gattttactt ctagtttttc tatggtttct tgatttaaaa ctatttcata
    13861 ttcattaata atctcaaatg gcgatacaac aacaaatcct ataccttctt cttcagtaga
    13921 attaaattct tttaaagaat cattatcttc tatatctaaa agctcatatt cttttaaatt
    13981 ttcaaaccct aatatacctt tttttaatgt aaccttcatc atatctgcgt tatttttact
    14041 atatataatc taatatagat acactaaata actttcctcc tgtttgtagt gaagcttgat
    14101 aagttaactc tgctgccttt aattgaacaa gcttttcacc atagtctatt tcttcatttt
    14161 gtgacagaat ctcctttaac tgtatcaaac tatcatcatt tttttccttc atagcctcta
    14221 ctgtatttgc ttttgtccca tatatagacc taacatttac tgtattttct attagttgtt
    14281 ccatttcacc taaacaagtt gttgtgagct cttttatagc atcagcatct ggatttgcta
    14341 atttctttga tatattattt aactcttcaa acgggtcagt ctttgttggg tcaaatccaa
    14401 ggctactcaa tttaacatta tagtctacac ttattccttg agctacgtcc atacttaaag
    14461 aatcttttaa tttattaaga tctatactag aattaaactt taagcttact gagccatcag
    14521 cattatctac acactcaaca ggtggtatac ctgtatttga acctgaaaat atgtacttac
    14581 cttcatgtgt tgcatttaaa gcatttgcaa tttcttttat tttttcattg gtttcattac
    14641 taagggtctt tagttcgtca tctgaatatg caccatcacc acttgccacc aaagttttct
    14701 ttatgtccga taataatttc ccaagctgat ctaatgcagt atcagtagtt tctaaccaat
    14761 ttcctgtatc tttacaattc tcaacataaa tctccatagt ttttatttca ctttttgagt
    14821 ttaatatttt tattgcttta tatggattat ccgatagctt gtttatttct ttggttgtat
    14881 taacttgtct attaactttg tccaatcttt gtagattatc ttgcagggag tttagataac
    14941 tgctagacat catacctgta ctaactctca ttataaattc ctccttctat taaattattc
    15001 catttattac aacatccaac agttgcacag ctgttgacat aacttttgca ctagcttgat
    15061 aggaacgttg tatttttata agctctgtca tttcttcatc caaagataca cctgaaacac
    15121 tcattcttga attatcaata ttatttataa ttttacgttg attcacttca tcttgattca
    15181 cttttttaga atctaaacct actaattctg caaaggcttt atagtggtca cttattgtac
    15241 ttacttttcc accagccact ccaatatcta ttttttcatc ctttaactta gcaatttttg
    15301 aagcctcatc agcagtaagc tttaattcat ttgggttact ctttatagct ggatttacct
    15361 ttatgatatc ttcaccatct acatttgaag ttacaaaaaa atctcttact gttattccag
    15421 cagacgtatt atagacatca tttatctgtt tagctaatcc atcagagacg tcttttaaat
    15481 cgcttttata tgtatcaatc ttaccatgca tttcaaataa tccttgtaag gttcctgata
    15541 cacctgtttt ccaagttcca tctgcatttt ttaattcatt aagttctaat ttaccatctg
    15601 caagcatatt tttaacatcg ctattttcaa aatctagctt aaagctcaag ttgtctaata
    15661 ttctatctct ttcatcaagc aaatcatttg gcatagagcc agaaccagag ataatatcaa
    15721 tagatttatt caaatcttca agacttttta acatttcatt gatttgtttt atctcagtat
    15781 ctatattaga atctatatct ccttttaact tgtcaagctt cttataactt tcgcttatta
    15841 aggttgctaa attagatgca ttttctacta ctagactttt tttactgtca ctatttatat
    15901 cctttgataa cgactcccat cctttaaaaa aatcatctat acctgcagat attccatagt
    15961 ctgatggttc atttagtata gtttctatag tattataata atcatatttt gaaactgtct
    16021 taccatactt atgagcttct gctctaaatt ggtaatcata aaaactattt ctagctcttg
    16081 ttacatctgt tacatgtact ccagtaccta attgtcctct tccaattgaa ttactcaaac
    16141 taggcatata catagggcta tttgtagcaa actcagtcct ttgcctagaa taaccttctg
    16201 tgtctaggtt acttatatta tgagaaattg tctgtattgc tttttgatgt gagttcattc
    16261 ctgaattagc tgtatttaaa atggaaaata atcctgccat atttctcctc ctaatattta
    16321 ttttctaata tttccataag aattataagt tgttgtttgc ttatcaactg gttttatgaa
    16381 attaatcatt ttttttgtaa aaataagttc tttctttatc agagaatcat ttgattcttg
    16441 ttgattttta gctaaagcaa gaatgtgttt taggtctgta tatatttctt ttaaatatcc
    16501 atctttacta ttttcaacaa cctcactcat tgaaatatca tcaccaaaaa gctgtcttct
    16561 ctttatttct atggatgcaa gttccctact aatatcttct agtttaggat ttaacatatt
    16621 taaattttct aagtcttttt caactatata atcaaattgt tcttttaata attccatcat
    16681 cttactaatt atattttttt cttcatacat tataactttt aagtctgtaa tcatgacttt
    16741 atcctcgcat atcctctatc attttttttg caatttcttt tggttttatt ttgtaagttc
    16801 cattttctaa tgcatttttt atttcatcaa cttttttatt cctaatactc tcatcactca
    16861 tatttgatac acttgccatt tcctttgcaa acttagatag ttctatctta tctgttttat
    16921 taattttttt aacatcttcc acttttttta caccagatgt attctttaaa taattattca
    16981 ctacaatatt tgaacttaca tttttaatat ccatagtttc acctccaaaa ttacatactt
    17041 ataatttaat tatcgctcag aaaataaaaa catttatata attcacacat attttaaact
    17101 ttttataaaa atatcccctt agctaaactc atacagagta gcctaaaggg atactattta
    17161 aaatgctaat ttatatctga atcttctatt ttagataatc ttacagataa cttctcattt
    17221 gtaataatac tttctccata agcaaacaat ctatcatttg catatatatc taatttttca
    17281 tccacattct tatttagttt tattatagag ccttctttta aatctaatat attttttatt
    17341 gtttctgttg tatttcctat agaaacagct acatttactt ttgcattaaa aacattttga
    17401 ttttcttcta taataccaga ttgttcttct attagttgcc caaaattcaa ttcatatata
    17461 tcctcttttt tactattcat aaaacttttc tccttgtata atcttatcta tacatatcta
    17521 tcaacaaacc ttgtatcata tcaacagtag aaacaatgtc tatgttttct ttttcttcac
    17581 taattaactt actagtcata tcctcaagtt tactgtcaac aatctttaca ttcttataat
    17641 actgatgttc ccaaaaacta ctattcttat caagtgaata catattatct acaacagatt
    17701 ttaggtattc ttttactgca tttttatata tactaatatc gccatagttt tgagtaagta
    17761 caagcctttc tcctgccttt tttacactct ctaaatttcg ttttatatct tctagtgaag
    17821 aagattgttt taaagagttt aatctatcag aaaatttatt attttctttt agttttttga
    17881 cttctatatt tatacttgga cttattttta gcttatctat atttataccc ataataaagc
    17941 ctaccctcta taatatttca taaccttagg aatataattt tgtgtttctt ttggcatttt
    18001 atacaggtca gaaattgatt ccactcctct actcttcatc cttccaggac caccattata
    18061 tgccatcaac cccatttcta tacttcctcc aaacatatca atatattcct taatatgtct
    18121 agttccagca tctatattct gctctatatt aaaagggtct gtaacaccca aatctctaca
    18181 attttctggc ataagttgca taagaccctt agcaccagca gaagaaacag tatttggatt
    18241 aaagtccgat tcaactttaa ttattgcttt tataagattc gcatctacat tatatttttt
    18301 tgatgcttgt tctacagcat tttcaattct caactttaca tttttatctt ttgtatcaac
    18361 atctataaat ctactagtgg tattatttac tacattctca agttcattaa acaaattctc
    18421 agaattagac gatatattat agccattaga agtatgttga ttattttgtg ataatgcttt
    18481 taacaaggtc atcataatca tatcaaatcc agatgaatta ttatatgtac aattacattg
    18541 atttgtatta ttactaccag ataattgagt caatgctaat atattaatta gtgaacttat
    18601 ctcattcaat ataaaacccc ccttctaaat tttataaatt tcaaagttac actgataaaa
    18661 cagatttcca ccaagattca ttttctatgt accacttaac agtttctttt ataccaaaat
    18721 caaaatcata ttttgccttc caacctaact cattctgtat tttagatgca tcaatagcat
    18781 atcttaagtc atgaccaggt ctatcattta cataggatat taaatcctca gatttaccta
    18841 aaagatttaa tataattttt actactttta gattacttct ttcattatga cctcctatat
    18901 tgtaaatctc ccctatattc cctttatgta ttattaagtc tatagcagta caatggtcat
    18961 atacatgtaa ccagtctctt acattttccc cattaccata tactggtaat tgtttatttt
    19021 ccaaagcatt taaaatcata agaggtatta atttttcagg aaaatgatat ggtccataat
    19081 tgttggaaca tctagatata gttgtcaaca atccatatgt tctataataa gaacttacca
    19141 ataaatctgc tgatgcttta gaggctgaat atggagagct tggatttata ggtgattgtt
    19201 ctgtaaagaa taaatccttt ctatcaattg gcaaatcacc atacacttca tctgtagaaa
    19261 tctgatgata ccttttaacc ccatatttta tagatgcatc taaaagtact tgtgttccta
    19321 taatgtttgt ttttataaat aaatcaggat tctcgactga cctatctaca tgagattcag
    19381 cggcaaaatt aacaactata tcaaaccttt cttcttcaaa tagcttatac atctgttccc
    19441 tatttgaaat atctcctcta acaaatttat aattggaatt gtcttgtatt tctattaatg
    19501 tctctaaatt accagcataa gtcaacaagt ctagattaac aataaaataa tctacatact
    19561 tattaagcat ataatgtaca aaattgctcc caataaatcc tgctcctcca gttatcagta
    19621 tctttttcat attttttctc ctaaatgtta attctaataa atttttatta acgtcttata
    19681 cagatatctt taaaactttt ttgtttttta tccttttctg ataaaaatat ttcttcaatt
    19741 ccttttaaag gccactcaat agatatttgc ttatcattcc atataaaacc attctcaaat
    19801 tctggataat aatagtttgt acatttgtaa ttaaatactg ctttttctga taaaactaaa
    19861 aatccatgtg caaacccttc tggaatataa aattgttttt tattcttatc agacagtatt
    19921 acaccttccc attctccaaa tgtttttgaa tcttttctta aatcaactgc aacatcgaaa
    19981 acttctccct ctgtaactct gactaatttt ccttgaggat atctaacctg aaaatgcatt
    20041 cctcttaaaa ccccttttct tgaactagac tcattatctt gaataaagca catatcaaga
    20101 ccttgctcta taaaatccct tttattatag ctttccataa agtatcctct ttcatcacaa
    20161 aatacacttg gttcgactat atacaatcct tctattttag tctttatgac attaattttt
    20221 cccattataa caaactccct taataaaatt tataataaat tttatctacc atattacata
    20281 tcttcactag ctaactttaa tagatattga ccatattcag tttttatcag tggcttggct
    20341 agttccatta attgtgctct acttatatat ccttttttat atgcaatctc ttctaaacat
    20401 gctatatata atccctgtct tgtttgaacc acttcaacat agttagaagc atccaataga
    20461 cctttatgtg taccagtatc aagccaagcc atacctcttc ctagaagttc tacttttaat
    20521 tttcctcgtt ttagatactc actgtttata gaggttattt ctaattcacc tctatctgat
    20581 ggttcaacta gctttgctat ctctacaaca tcattatcat aaaaatacaa tcctggtata
    20641 gcataattag atttaggaac tgtaggtttt tcttctattg acaatacatt aaaatcctta
    20701 tcaaattcta caactccaaa cgaatttgga ttacttacat gatacccaaa tatagttgct
    20761 ccttttcttt taactgcttt ctccaatctt tcactaaatc catatccata aaatatatta
    20821 tcccctaata caagagacac tctgtcattt cctataaatt cttctcctat tataaatgct
    20881 tctgcaattc catttgcttt ctcctgaatt gcatatgtta ttttaagacc taatgaactt
    20941 ccatctccaa ataattcctc aaatgctttt atatctcttg gtgtagatat tattaatata
    21001 tcttgtatcc ctgccaacat aagaaccgac atagggtaat atatcattgg tttatcatat
    21061 attggaagtg tttgttttga tatacatttt gttataggat atagtcttgt accagaccct
    21121 cctgctaaaa taattccttt catctttttc catccttaaa tttgtttttg tcatattatg
    21181 attatcggat aaataaaaga aatatttata ttttttataa tatcttattt tcttttctaa
    21241 aaataataca tttactcttc attcatatca tatctttcta aatattcttc aatggattct
    21301 tcccaatttc taaaagaatt taaaccaatt aacttcaaca taaaattatc caatacagaa
    21361 tataatggtc tttgagcctt acatttaaat tcgttactct taatcggatt tacttttatg
    21421 tctatatttt ttaattcaaa tatctttttg gcaaaatcat accaactaca ctcaccttca
    21481 catgtagcat gataaactcc ataatgttct gtttccatta ttcttattat aatttttgtt
    21541 aaatctactg tgcttgttgg agttccaaac tggtcattaa ctacattaac ctctttattt
    21601 tctaaagaaa gttttatcat agtctttaca aaattattcc cattaccata taaccatgct
    21661 gttctcaata taaagtactt atgtgaaaat tgttcaacaa acttttctcc cataagttta
    21721 ctttttccat acacagaatt gggttcagtt ttactgtctt ccctatatgg atatttagaa
    21781 aaaccattga atacataatc agttgatatg tgaataagtt tagcattaac tttttctgat
    21841 gctattgcta gatttcttac tcctaaggca tttactttat atgcagtttc tatattatct
    21901 tcacatgcat caacctttgt atatgctgca cagtttacaa ctacatcagg tttattattc
    21961 aaaataaaat tatctacatt agtctgatta tatatatcaa aatcattcct tgttgtagct
    22021 aatatagcat atttgggttg actcatactt tgattgattg cttctaattg gttaaccaat
    22081 tcttttccta attgaccatt agaccctgtt attaatattt tcattaatta tgttatcctc
    22141 caataaatgt tcaattttac ttaataatta attataacac agcttgcatt ttaacttagg
    22201 ttgaacttat tatttcttat ataaataaaa aagagatgta atattaaatg attatcatca
    22261 tattattaca tctctttaaa tctaaatata taaaatatat tgtaattacc aattaattat
    22321 tagaaactta tctaaaatat ttaactccag attcaaatat cttttggtct ttttcaccta
    22381 taatgttctt aaatacttcc tcaccaattc tctcagaatg tcccatctta ccaaacactc
    22441 taccatcagc actagttata ccttcaacag catagaatga accatttgga ttaaactcaa
    22501 tattataagt agcttcatta ttaaaatcaa catattgagt cgctacttgt ccattagcaa
    22561 ttaattctct cataacatct tcactagcaa caaatttacc ttctccatga gaaattgcta
    22621 tattatgaat atctccaaca ttagtttgag ctaaccaagg agatttatta gatgaaattc
    22681 tagttctagc aatcttagct tgatgacgac caatattatt gtaagtaagt gttggagcac
    22741 tttcacttgg aactcttatt tctccatatg gaactaatcc taatttaatt aatacttgga
    22801 atccattaca gatacctaac attagtccat ccttttgagt tagaaattca tttatggctt
    22861 cttgaactct cggatttcta aatacagtag ctataaattt accagaacca tctggctcat
    22921 caccagcact aaatccacct ggtaacatta ttatttgaga agattttatt tcatttacta
    22981 ttgtatctat agaatcttct atatctttat aagttaaatt cttaaatact cttatgtttg
    23041 cattagctcc tgctctttca aatgctcttg cagaatcata ttcacagttt gttccaggga
    23101 atgctggtat gaatactctt ggagtagcta tacttagtga tgatttttta gcttctcctt
    23161 gtgatatata acttatagtc tctatctttg attttacttc ttctgcttta gttgggaata
    23221 taggctctaa agtactacaa tgtgatttat ataattcatc taatgcaagt tcttcacctt
    23281 tgataaatat actagcttct ttaactgtac ttccaagcac aacataattg tatccttcta
    23341 acatacttaa atcatcattt gctaattcaa gtactatatt tccataacta gcctcaaata
    23401 atttatcatc tttaaatgct ttttcagttt cttcactaaa cttaaatcct attttattac
    23461 caaaagccat tttacttatt gcttcaccta cacctgcaaa tcctaatgca tatgttgata
    23521 aaattttatt tccatgtata agctctctta ctttgtctaa gtttctcttt aattcatcaa
    23581 aatctataac atcattttct gccttgttta cgcataacat tactactttt gaatctattt
    23641 ttttaaattc tggagatact actttcttcg catctactgt atcaacagca aatgaaacta
    23701 atgttggtgg aacttcaata tctttaaatg taccagacat actgtctttt ccacctatag
    23761 caggtatctc aaatttactt tgtgcataaa atgctcctaa aagtgctgag aatggtttac
    23821 cccatttttc tggattgtta ccaagtttct caaaatactc ttggaatgta agtcttgttg
    23881 tactgtaatt tcctccaatg gcaaccaatt tacacacaga ttctactact gcatacaaag
    23941 caccatggaa tggactccat tttcctacct ttggattgta tccataagtc attattgtag
    24001 aagtattagt ttctcctcca agcactggta tcttagcaac cataccttgc gttggagtag
    24061 cttgatactt tcctccaaat ggcataagta ctgtattacc accaattgta ttatcaaaca
    24121 tctctactaa tcctttttga gagcaaacat taaggtcaga caataccttt ataaatttgt
    24181 ctttcatact tgcacactta acatctttta ctatttcatt agagctaaag aatgtatttt
    24241 cttcatctac tttagtaaca cggacatcag tagtttgttt tactccattt gtgtccaaaa
    24301 actctctatt tatatctaca attgcttttc cattccagaa cattcttaaa tatcctgtat
    24361 ctgttactgt agctacatgt gtagcttcta agttttcttc tactgccaat tgtataaatt
    24421 tatctttatt ttcttttttt atagctactg ccatacgctc ttgtgactct gaaattgcaa
    24481 gctcagttcc atcaagtcca tcgtattttt taggcactaa gtctaagttt atatctaaac
    24541 tatcagcaat ctctcctata gcaacacaaa ctccacctgc tccaaaatca ttacatcttt
    24601 ttatcatttg agcaacttct ttatttctaa agaatctttg tatctttctt tcgttaggag
    24661 catctccttt ttgaacttct gcactacaag ttaagattga ttcttcacta tgctctttag
    24721 atgaaccagt tgctcctcca cagccatctc ttcctgtttt tcctccaaga agaactatta
    24781 catctcctgc ttcaggtctt tctcttacta cattttcctt tggtgctgct gctataactg
    24841 cacctatttc cattctcttt gcaacaaagt tttcatcata tacttctgca acttgtccag
    24901 ttgtaagacc tatttggtta ccatatgaac tatatccatg agcagcttct gtcgttattt
    24961 ttctttgcat aagttttcca ggtaaagtgt cctctaaagt tgttcttggg tcagcacttc
    25021 ctgtaacacg cattgcttga taaacataac ttcttcctga taacgggtct cttatagctc
    25081 cacctaaaca agtagctgct ccaccaaatg gttctatttc agttggatgg ttgtgagttt
    25141 catttttaaa cattactaaa tacttttcca tcttaccatc aacttcaaca tctacattta
    25201 tactacaagc atttatttct tcactttcat ctaggtcatt taatttccca tttttcttta
    25261 attcttttac tgcaacagta gctatatcca ttaaacatat atctttatgt ctgttcacat
    25321 atacattgtc tcttgagtta agatacattt gatatgcttc ttttactata tcattaaact
    25381 taccatcttc tatctttaca ttttctattt cagtcataaa agtagtatgt ctacaatgat
    25441 cagaccaata agtatctaga acttttattt ctgttatagt tgggtttctc ttttctgtat
    25501 ccttaaagta tttttgaacg tgttgtaagt ctcctaaagt cattgctaat cctttttcac
    25561 ttacaaatgt tcttaatcca tcttcatcta aatctataaa tccatctaat acttcaactg
    25621 ttgttggtat ttcagtttcc atttttaatg tttctggttt ttctaaagat gcttctctac
    25681 tatctactgg atttatacag taatctttta ttttagaaaa ctcttcgtca gttattttac
    25741 ctgataatat ataaactttt gctgtattaa tagcaggtct tatcccttga tttacaattt
    25801 gtacacattg agctgcccaa tcacctcttt ggtcatattg accaggaaga aattctattg
    25861 caaatactct ttcatcattt aattttggta tttcttcata atatactaca tctagatttg
    25921 gttcagagaa tattgtcttt gctgcatttt cataaacttc ttctgatatt ccttctacat
    25981 catatctatt taatattctt aaattttcta tattatctat gtgtaaactt tccaccaagt
    26041 ctttttttaa agctttagcc tcaaggtcaa aaccttctct tttttcaact agtactcttc
    26101 taaccattga gtctttattt tcagtattca acatacctta tcctccattt tagaaaaatt
    26161 atcttcctat gtctgttcta tagtgcattc cttcaaagtt tatcttcttt atattttcat
    26221 aaactttttc tgctgcatct ttaactgtag ctgactttgc agttatacca attactcttc
    26281 ctccattggt aactaaatta ccatcaagca tcttagtgcc gctatggaat actactatat
    26341 catcatccaa gttttcaaga ccagttataa ttttcccttt ttcataactg tctggatatc
    26401 ctcctgatgt aagcataaca catacagctt catcatcact ataatttatt tctatatctt
    26461 ttaacttatt atctagtata gattccatta tctcatgtaa atctgtttct aatctaaata
    26521 aaacagattg tgtctcagga tccccaaatc ttacattata ttcaagtact ttctctccat
    26581 cttcagttat cataagacca acaaataaaa tacctttaaa atcaagtcca tcttttttga
    26641 aaccttctaa agttttttct aatactgtct cttttactct atttgctaat tcttctgtat
    26701 atatttcact aggtgaaaaa gttcccattc ccccagtgtt tggcccttgt tcatagttgt
    26761 ttactttctt atggtccttc gcacttgcca taggaactat tgtatcatta tctacaaatg
    26821 ctagaattga agtttctatt ccttttaaaa actcttcaat tactatttta tctccagcag
    26881 ctccaaactt cttatctgac atcatttctt ttaaagttgc tatagcatct tctctatttt
    26941 caggtattac aacacctttt ccagcagcca atccgtccgc ttttattact actggatatc
    27001 caaagttatc tatttctgat atagcttctt ctaagtttgt atattcttta tattttgcag
    27061 taggtatgtt atgttttatc ataaattctt ttgaaaaagc tttgcttcct tcaagttgag
    27121 cacatttttt attaggtcca aatactctta atccttcttt ttcaaactca tctactattc
    27181 ccataactag tggtacttct ggtcctacta ttgtcagacc tatttcattt tctttggcaa
    27241 attttaaaag ttcttctata ttagtatcac ctatatttac gcattctgct acatttgcaa
    27301 ttcctgcatt acctggtgca caataaattt tttctacatt cttttctttg cttagtttcc
    27361 agcatatagc atgctctcta ccgccaccgc ctacaaccaa tatcttcata atatcctcct
    27421 tagtgtttga agtgtcttat tcctgtaaat accataacca tatcatactt atcacaagct
    27481 tctattgaat ctttatcttt tatagaacca cctggttgaa ctactgctga tattccatat
    27541 tcatgagcta atgttacaca atcatcaaat gggaaaaacg catctgacgc taaaacagct
    27601 cctgtaaaat ctttatcttt gttattttca agagcatttt ttaatgccca aattcttgag
    27661 gtttgtccac aacctaaagc tagagtttgt ccatttttta ctattgcaat tgcatttgat
    27721 ttcatatttt ttactactct cataccaaat tccatgtcct taagctgtgc atctgttggt
    27781 tttgcctttg ttacattttc acttttttct gctaatatat tatttctatc ttgtatcaat
    27841 aattttccat ctaaatattt catttcatat ggttgtaaac tattttctat tttagctaat
    27901 tttaatattc ttagattttt cttttgctta agtatctcta aagcttctgg ttcaaaatca
    27961 tatgccacta ctatttctaa gaatatttca tttaatttct ctgctgtagc tttgtctata
    28021 gtagaagtta ttcctactat tccaccaaat attgaaacct tatccgcttc ataacatttt
    28081 gtatatgctt caaaggcatc ttttcctaga cctaccccac atgaattagc atgttttata
    28141 gctactgaaa ctacttcttc gctatcttta aattctctca ttacttctaa acatccatgt
    28201 aagtcattta agttgttaaa agaaagttct ttaccgccta attgctcata atttaagatt
    28261 ggattttttg catttgattg tgaatataag aaaccatttt gatgtggatt ttctccatat
    28321 cttaaagttt gttctttttg gaaagttaaa tttaatatgt cagggtacgt atctccaact
    28381 tctccagcaa aataactaga tattaacgcg tcatatcttc ctgtagttga gaaagcttta
    28441 tatgataatt tttttctgtc ttctaatgtc attgtatctg tttttaattt ttctattata
    28501 gaatcataat cttttatatc tactactact attacatctt tatagttttt ggcagcagaa
    28561 cgtatcatag atggaccacc aatatctata ttttcgatta tttcatcatg actttttcca
    28621 gcttttaaag ttccttcaaa atcatataga tttacagcta ctaaatctat tgaatgtatt
    28681 ttatgttcat ttacagtttc tacatgagat tctttatctc ttttataaag tataccacca
    28741 tgtatatatg gatttaatgt ttttactctt ccatctaata tttctggaaa atttgtaaca
    28801 tcttcaactt gcattacatt aacaccattt tcttttaatg ttttaaatgt atttcctgta
    28861 gatataattt cataatctaa cttatttaac tctttagcaa attccactac accagtcttg
    28921 tcagttacac ttattaaagc tctcttactc atttataaac actctcctac cttgaagttt
    28981 taatttattt tcacaaaaaa gacttatact ttcttttaaa atcctatgtt caacttctaa
    29041 cactcttttt gcaagtgtct ttgcatcatc atcttgattt accttaacta catcttgcat
    29101 tatgattggt ccagtatcag caccttcatc aacaaaatga actgtagcac cagttacttt
    29161 agctccgtaa tcgataacac cttgatgaac tttttctcca tagaatccag ctccacaaaa
    29221 tgaaggaatt aatgatggat gtatgtttat cattttgttt ctaaactcat taaccagctt
    29281 tgggctgatt atttttaaat aaccagccaa aactactaaa tctattttat tttccttaag
    29341 aatttctatt atcttgtctt catcagtttc acaaattgct tttatgttat gatttttagc
    29401 tctctctagt ccataagcat cttgcttact tgaaataact actttaacct gaccttttat
    29461 ttctccagac tcagtgccat ctataactgc ttgtaaattt gttcctccac cagatattaa
    29521 aactcctata tttagcataa ctctacacct tcatgactat ctactacttc accaattata
    29581 tacgctttat cttctaataa ttcactgtat tttttatcta cataagcagc attgtcattt
    29641 tctctattat ttataaagtt tacaacatca tcagcatttg ctttatctac tattaaaact
    29701 agcccaatgc ccatgttaaa acttttatga agttctctct cattaacagc attaaaacct
    29761 tctatcattt taaatatagg aggcttctcc cacgattttt tattgatatc tagtcctaag
    29821 cctttaggta taactcttgt tatattttct ataagtcctc caccagttat gtgagctatg
    29881 gcttttattt catgtttagc taatacatct aaagccaatt taacatatat tttagttggt
    29941 gttaaaagtg cttctccaac tgtcattcct agttcttcaa catattgttc cattttataa
    30001 ttgtaagttt ctaaaaatat ctttcttata aaagaaaatc cattactgtg tactccactt
    30061 gaagatatac caaccaatac atctcctgac ttaacattat ttccagaaac aatcttttct
    30121 ttgtctgcta ttcctacaga aaatcctgct aaatcataat catcttctcc atacattcca
    30181 ggcatttcag cagtttctcc accaattaat gcacaaccag acattttaca accgtctgca
    30241 attccaccaa ctattttttc aatatgctca ggaactaatt tcccaagagc tatatagtca
    30301 aggaagaata atggttttgc tccttgacaa attaaatcat tcacacacat tgcaactaaa
    30361 tctattccaa cagtatcatg cttgtccatc atttgagcta tttttaactt agttccaaca
    30421 ccatctgtag atgcaagcaa aactggctct ttcataccta caaaatcttt taaactgtat
    30481 aatccgctga aattacctaa atctccaact acatttccat cataagttcc ttttatttta
    30541 ccttttataa ggtctactgc tctatttcct tcatctatat ctacacctga ttctttataa
    30601 gttaacatga aagtagttcc tccttatcaa ttttcttaac tgggtattct ccatcaaaac
    30661 aagctttaca gaaagtagac ttgtgttctg ttgcatctaa cattccttct atatctagga
    30721 attttaaact atcacatcca atgtattctc tcatttcttc tacgttgtta cttgatgcaa
    30781 ttaatttaga gcgatttgga gtatctattc catagtaaca agaataagct actggaggag
    30841 aagttattct aagatgaatt tcttttgctc ctgcttctct taaagatttt actaattgtt
    30901 tagatgtagt tcctcttaca attgagtcgt ctactaaaat tatagacttt ccttttatta
    30961 ttgttgaaag aggatttaat tttattttta ctgctatttc tctttcttct tgtgtaggtt
    31021 ttatgaatgt tcttcctaca tatctatttt taactaagcc ttcacttatt tttaatccac
    31081 tagcatttgc ataaccaata gctcctggcc aacctgaatc tggaactgga actaccatat
    31141 cagcttttac agtttcattc tgagctaatc tttcaccaca tttaattcta aattcatatg
    31201 catttacatt gtctatagtt gcatcatttc ttgcaaagta tatgtgttca aatatacaac
    31261 ttttcttaac tggtttataa ttttctgaat aaaaatatga ttttagttct ccatctttaa
    31321 ctactattat ctctcctggc tctacatctc ttataacttc tccgccaagt atatctattg
    31381 cacaattttc tgatgcaaat atatattcat cacccttttt accaagtaca agaggtctga
    31441 atccatgtgg gtctctaact gcaaccaatt cttcttgact cattattaca agggcatatg
    31501 caccttttat ataatccatt gtcactttta aactttctac tatatcccct ttgtaatatc
    31561 tcgcaagtat atataaaatc acttctgtat ctgaattagt ttggaacata tatccatctt
    31621 cttctagcat atcttttaaa taatttgcat taactagatt tccattatga gctatggcta
    31681 attgtctttt tctacaactt ccaactaaag gttgacagtt agaaacatga cttcctccag
    31741 ctgttgaata tctaacatgt ccaatcccta tatttccttt taacttagat aattcacttt
    31801 ccttaaaaac atctccaact aatcccatat ctttcttgta cttaatttct ccatcatcta
    31861 aaagagctaa accacagctt tcttgccctc tgtgttgcat agaatataaa gaataatata
    31921 gttctttagt tacatcttta ttagagtaaa tccctaaaac tccacacata catttgcctc
    31981 ctatttatta ttcattcttg aaagtacttc cgtataacct tctacaaggt ctccaaggtc
    32041 ttttctaaat ctgtccttat ctaacttttc atttgtgttt acatcccaaa gtctacaagt
    32101 gtctggtgat acttcatctg ccaatattat atttccttca gaatccttac caaattctat
    32161 tttaaagtca actaacttta ggtttaattt taagaaaaat gcttttagta actcgtttat
    32221 ttttaaagtt tcttctctta agaactttaa ttcttctcta gttgctaact tcattgctac
    32281 tgcataatca tcatttaaca ttgggtcacc ataagcatca tttttgtagc ttatctcaaa
    32341 aattggctcg tcgaaaacta caccttcttc aagaccaact cttttacaaa tagaacccgc
    32401 agcaatattt cttactatta cttctaatgg taaaatctct acttttttaa ctaacatttc
    32461 tctatctgat aaactcttta taaagtgagt atttatatta ttttctttta acatttcaaa
    32521 gattattgtt gatatcttat tatttagtat accttttgaa gatatttctg cttttttttc
    32581 tccattaaat gctgttgcat catctttata ataaacaaca tattcatttt cattatctgt
    32641 agaatatact tgttttgctt ttccttcata taataacatc tctgctaccc ccttaaattc
    32701 ttgtcgtctt ctaacacctt ttgtgccatc tcttctctat atgatttcaa atcctctttt
    32761 aattttgggt attttaaagt cattatttgt aatgccaata aagctgcgtt taaacctaag
    32821 tctattgtaa ctgttgcaac tggtattcct tttggcattt gaactattga taaaagtgag
    32881 tctagtccat ccatagttga tgatttaata ggtaatccta ttacaggaat taatgtttgt
    32941 gaagctatta cacctggtaa gtgtgctgct tttcctgctg ctgctattat tacatcagta
    33001 tcatcttcta tttcttttag gaatgttgaa agttgttctg gtgttctatg agctgatagt
    33061 gctcttgcta caacttctat tccatatttt tcaagcagtt ttatcccttc ttctaacttt
    33121 ggataatctg attttgaacc cataactact gctactttca ttagacttcc cctctccgtt
    33181 tataagttat tttacactat aaatcattcg tatgattata cgaattatac accttaaatt
    33241 ttatattaat atacatatat tatcaactct tttttgaaat ttttaaaaaa aaatatttct
    33301 tgtatttttt tattcgtcac gtatcgaact ttatttatgt ttttttatta aaataaaaaa
    33361 cagattatct caaaattgat ttttctaatc agattttaaa cttaatctcc tttttaaaat
    33421 tttgtatatt attttttatt acttattttt taattaatat cttaaattta tagtcttgtt
    33481 ttttaactct gaatgttact ttcgcttgga taaaactaat acatagttta ttctttatct
    33541 aagtaatagc taaaacttaa agtgatgata ttatatagat agatataatt ttatttaaag
    33601 gagaatctgt atgttagaag ttataaaaaa tagacgttca ataagagcat atataaataa
    33661 aagcgtagaa gaagagaaaa taactgaaat actaaaatca gctatgcaag caccttcatc
    33721 aaaaaatgct caaccatggg aatttatcat agtagatgat aaggaactac taaaaaaact
    33781 ctcaaaatca caacatagag caaagcatat agaatttgca ccattatgta tagtagtgct
    33841 tggaaataga gataaattct taaaacctgg taaatggata caagatttag gtgcttgcac
    33901 acaaaattta ttattagagg ttactaacca aggtctagct gcttgttggg taggagtatt
    33961 tcctaaaaat aaagtggtaa ataaagttag acaaacttta gacttaccag taaaattagt
    34021 accttattca cttatatcta ttggatatag tgaagaaaaa aatgaattta tagaccgatt
    34081 tgatgaaaat aaaatacata gaaatatata taaaaataga tagtgtttta tttcctctaa
    34141 actagctggg acataaaaat ctcctatata tactagtgct atattagggg atttttcttt
    34201 gttttgtaat tgatattaaa aacaagactt aagaccttgg ttttattttt aaaattcatt
    34261 ttatctaact ataaaattta agatatagaa agtacagcag ttaattattt taaatttgtt
    34321 gagaatatct taaaattagc cattttcctt aaaatatttt agtaaattaa tacttcctat
    34381 caaaacttca gtaaaaatat accacttaat tattattaag attaatcttt gtacaaaaat
    34441 tcatattgcc tcttaaaaga gtacatacaa ataaatttta tctaattggc atttaaataa
    34501 actatcttac aagtatttaa tagtaactct cctacaaaat tttattagta tatgagttaa
    34561 ctaaatttta atataaagag aacataaaat actgtaaaaa agtgttatgg ttatttcgtt
    34621 gaaaagaaag acatactatt aaagcataaa ttaaaatata ggagatgatt aaatgagaat
    34681 actttcagaa actgaaaaaa tatccttagc agcagttata aaaatggaat ctgatggatt
    34741 acttatgcaa agagcaataa atatgttaat atcagatgaa gacctaaaaa gacaatcaga
    34801 atctagtata ttagcaacag aaggaagaat taaagctata caacaattta tagttgaaaa
    34861 tgaaatacta atttctgagg aggtatagat aatatgagaa atatgataga aaatctaatt
    34921 aagaacaata cttatataga cgataaagta ataatgttaa gtatgctttc atctgctaaa
    34981 gcatctgcca atatgtatct taattctgca ttaacaagta gtacacctga attaagagct
    35041 atatattcag cttcactaac tcaaatggtc gaaggtcata cagcacttac agaattaagt
    35101 attaataaag gatggtttaa accatatgat aaacctattc aacagttaac atgcagttat
    35161 aaagaatccc aaaatgttat tgactaaact aaataaaaca tatttctaac tatttcactt
    35221 taattaaata ataaaaaggg gatattcaaa ttttttaaga tttccccttc ttctaaataa
    35281 tctatttttt aatataaaat agattgctta caatctaaag atataatttt atatagttat
    35341 tattaattat tttagacaat tctatttatt aacatttttt actacatatt tttataaaca
    35401 aagacatcaa atccttatgt tccaaaatta aaaaatcagg cttataaaac accccttcta
    35461 cttcatgtct cctatggttc aaccatatac tcttccaacc agctttttta gctcctaata
    35521 catcatttct ataagaatca cccatataat atgtattttc tctatctaaa ttcataacat
    35581 tctcagctac tctaaaaata ttagtatctg gcttagaaaa tccaacctca ctagatataa
    35641 aaatattatt tttatcaacc cagttttcaa tatttaactg ctttaacttc attctttgat
    35701 gagttgatgg accattagtt ataattccta gattaatatt cctttcttta gaaaaattta
    35761 aaacccactc aacttctggt attagtgtaa tttgtgattg ttggtatata tactcatctt
    35821 gaaaactttg tgcatctttt tctgtaatgg aagttcccaa ttcctcaaaa gctttcatta
    35881 ttctataaat atgcatttct ttgattgcca tttctccatt ctcagtcata tgaaatacct
    35941 catcactata ttttctacta ctcatatata agtcttcaat agaaatattc tttattgaag
    36001 aaaacacttt attatatgca atataaaaag gtgttaattg attatataaa gtatcatcta
    36061 catcaaaaat taaattaatc aaaatattag tcctcctaaa tttaatagtg gtaagtataa
    36121 ttataactat aaatacctag tataacaata ctcaccacta taagtcccat tatttattta
    36181 aaatccttgt agtaacacct tttaagttat aacattccgc ataatcacgt aaaggacgtt
    36241 taatgtggtc tataacaaat ctttgaccat caatattatt cttacttaaa ttagcataaa
    36301 gcacttctat ttcttttttg acatcatcat tattaaatgt ataatgccct gcaatatcta
    36361 atatttcatt agataaaact tcattcttaa atatatcttc agtagttaga tttttttgtt
    36421 ctcctattac ccattttctc caacgtccac attcaattgc attaacaaga agaacatgtc
    36481 tgatattaga agttttatca actaaaccct ctttttctaa tttacactca acttctgcta
    36541 attttaaata tgctctagtt tcttcagtac catattgagg agctacattt gtagcaataa
    36601 tactagatgg tatatgttct aataaagtta catcatctaa gtaatcacca ttatgctctt
    36661 ttaaaccaac tccatatttc ttagccattt gagctaaatc ataagcattt ctaaaattaa
    36721 aagttcctac ttgttctgtc tttctagtta aagtaccagt ttgaccaact ataaatgttg
    36781 gcattggcaa acctctctta tcaagttcaa cttttagtct agttataaat gtttcatacg
    36841 tctcagttga agtcagacct ccattggttt cctctgtacc aacttcataa cctatttctg
    36901 gtagattgag tctttttctc tcattttcac aatattcaat taattctaca gttctttcta
    36961 gtactacatc tagtggaatt acttttccaa tttcaaatgg gtcttttgta gggtcaatca
    37021 ttaataggtc aaaacctgct tcaatgtccg ctaaataaga tttttttcct aactccattg
    37081 cctcatcaac aggtaaatgg tcatttctct ccttatctct ttgccatggt ccaccatggt
    37141 ctctacataa ataatataaa ccatcaaatc caactttatc ggcaatcttc ttaatatctt
    37201 ttgtaaaagt ttcttgattc caaccattta catagccgcc acctagttca tctgcatcta
    37261 cttgatttct gctcgcaata aacattaaag gaaaatcatc atcttttgct aattcaaaac
    37321 ttgcttgtaa caagtttggt gacataggac caattcctaa aagagttgca cttttcccct
    37381 cttcttgtaa ttctagtaat ctttgtacga cagtctttat tggtaacttt ttcatgacta
    37441 tatctccttt tattctattt ttaagatatt ttcaaagatg tttttaataa aaatctcctt
    37501 aaaaacatct ttgagttata tgtaaaacaa atcaattttt attgaaaagt atcttttatt
    37561 ttcttaatta atgcatcaga tttcttaatt atgtcagata cactcattct tactactttc
    37621 tttcccttaa aacgttccat atttctaatc tcaacatcat tagtcaatat tacacaagtt
    37681 gcttcctcaa tctctttaag cgacaattca ttatctatcc cagagcttcc ttgagtttca
    37741 acctttattt ctatgccaaa ctttttggct gataattcaa gtgattcagc tgacatgtaa
    37801 gtatgtgcta ctccactagg acaagatgtt actgctacaa ttttcatatt cttatctcct
    37861 ttagacttat atttttatat atttactttt ttatacaaat tcctttctta tttatattta
    37921 taattcttca aatattaatt caatcgagtc atctaaatcc tcttcaattt cttcatcttc
    37981 tttcacgtct ttttttacta atttcattaa tattgcaaca actactgctc cagttaatac
    38041 tgatgcaata taccccaacc tattgtcaac tacgggtaat actatcagac ctccccaggg
    38101 tgcatgattt aaacatccta ataaaaaagc cataatgttt cctataatcg acccaaccat
    38161 aatacaaggt attactctaa cagggtctga tgttgcaaat ggaatagctc cttctgtaat
    38221 tccaacacat cccattaata gtgaagcttt tcctgaatct ctttcttcct tgctaaattt
    38281 ttttggaaac aataatgtag ctaatcctaa accaattgga ggtatacaaa ttgcaacacc
    38341 aactcccccc attaaatatg gaagtgtgtc aacttgagtt tgagcaaaag tagctgcaac
    38401 cttatttata ggaccaccca tatctgaagc tatcattcct cctaaaattc ctcctaaagg
    38461 aattttagaa acaccagaca ttccatttaa ccaattagtc atccatgtca taaaagaagc
    38521 tataggttct ccaattaaaa atacaattat accacctgta atcaatgtac caatcaaagg
    38581 ataaataaat atcgaaccta aagtcctcat tgtaggagct aatttaattt tctttaattg
    38641 taaaacaaca aatcctgcta taaatcctgc tatgatacca cctataaaac ctgcatttac
    38701 ttcttttgct aaatatgcac ctatcatacc tggagctaat cctggtttat ctgccatact
    38761 aaatgctata tatccaccta atataggaat gaataaggcc aagccggcag ctccaatttg
    38821 attcagttta gccaaccatc ctgtttcagg aacagcagct tgtccactta gagttactga
    38881 taaagcaaat aatattcctc ctgcaactac aaatggaatc atataagatg ttgctgtcat
    38941 aagatgtttt tgcaaaaact ttaaaattct cattttaatc ttccccctct attttttctt
    39001 ttataagatt ataaacagtt tgttcatctg aacatctaat ttgatttcta aaactttcat
    39061 gcatcaataa acgtgctaat ttcgataaaa tctttaaatg aagattattt tcattgtctt
    39121 ttgttactga tattaaaaat attaaatcca ctttttctcc ttcttctgtc cattcaatag
    39181 gagtatcaag ttttcctata gtaatacaag agtttttaac acccacactt tgactatgag
    39241 gaagacctat accatgtcca atataagttg acaatgtttc ttctctcttt aaaacatcct
    39301 ctaaaaattg atttttatct cttaaatatc cttcttttga tactacatca actaatgata
    39361 taatggcttc ttcttttgaa ttagcatgta ttttaaatga acattttaca ttaactaatt
    39421 tactcataca gttacctcct tctcatattt atgaattaaa ccttctgctt cttcctttgt
    39481 ctttgcactt tctaacatag aaataaaatt agtcttataa accattttag ttagattaat
    39541 tattgcagga atttgctctt ttttatcttt gcttgctaaa caaaatatga ttctaacctt
    39601 tttatctcca aaactaactg cttctttaca tattaataga cttatcgaac ttactttgac
    39661 taatgaacta tcattaccat gtagtaaagc aaattcgtta tcttttacag cataaaaacc
    39721 cacatttttt aaaatatcta taatattttc agcatattgt gatgatacaa aatcacaatt
    39781 agcaagtata tttgaactaa tttttacagc atcttcccat ttcatatctt catcaattat
    39841 ccttatggta tcaattccta ttaaatcgcc taaattaagt tgtctagata atgctctctc
    39901 atcactgtat ccaagttctt gacatataac acttaatact cttttttgag catcttcttc
    39961 taaaaagtcc aacctttttt ttattgacat ataattagtt aagacgttct ttctttttat
    40021 acctttttcc tcaaacttca aataatcctc ttcttgtaaa aatggattta tctcaataat
    40081 tgttttaggc aagtctatta ctatctttga tgttgttata atgaagtcaa tactttccca
    40141 gtctttataa tcttgtaact tatatgatgg aatactgtcc actatattta tctggtaatc
    40201 atttattaga ctatctttta acatagcaat tacaccatag ccaaatccac aaactaacaa
    40261 tatatttttg tagttattcc tctcatttct atgtatactt cctaaaaaat gtattgccaa
    40321 aagtattgtt tcattttcat tctttatttg atttaaaact ctgttctttt gaatagaaac
    40381 cttagtagct tcaagtacat attggtactt atctggtatt acatgaagta attcttcata
    40441 aatctgtatg ttctgtttga ttctctctat caatggggca atatgattta gtaatccttt
    40501 ataaagaatc atatcttctt taaaactaat ctctaatatt tctgacatat tgtaaattaa
    40561 atcttgaact ataatctctg tactaatcag atccatatcc tcatttaagc ttgcatattt
    40621 atttgtaaaa aatacaaaac tctttaacag aaaaatttgt tccttagtca actttttttg
    40681 aataattgtt tcaaactctt ggtcaaactt attttcaaaa catggctcac ttaatgaaac
    40741 agattctaaa ggatgttttt catctgaatg tatataccat gtaaaaagga aaatgtttga
    40801 cacataccat gtgaaagatt catcatttaa agtccatccc atttgcaata ataaattcat
    40861 agaccaatta tatatatcaa tcaaagaaat ccccttgaat attttttcaa tcacattcac
    40921 taaatacttc tcaaatacac ttaaatcaga tttttcttta ccaaaaagat aagaatatga
    40981 ttttaatata ttcaatcttt gcttatatat aatgtcttct tctccactta ttttaaaagc
    41041 tttatcataa gtaatagtta tttgatttct ttctaattca cttgataaaa cattaaggtc
    41101 atttttaatt gaacttctag aaacctgaaa ttctttactc aatttttcta agtttagatt
    41161 ctctatttta aacattgata taattttcat aatagatact cgctcagtta aggaaaatac
    41221 atattcgtta ttatttatac atactacttg gaagttatca ggaataatta acacaccttt
    41281 gttcatcttt tgtattactg gcttgtttaa tgaacgcaaa acaatattta aattatttat
    41341 atcatatcta acttttcttt cttctatgct aagttgtttg ctaatatcct tgtaacttgt
    41401 cttatttttt ccttttagaa aattcatgat gagtaacatt ctcccactta tcatattttc
    41461 cctccttcca aaataattag agttattaat atagcaaatt ttacattgtt atgtatgttt
    41521 tagttttttt atctaaaaca gtaactatct ttctatattc agaataatac aataaagctt
    41581 tagccacaac ttacaacatt tgaaaattat ttttacaaaa tctgcaaata cattttttat
    41641 taaatatata aataaaaaag gcaagttatg ttttaattat ataacttgcc taaatttttt
    41701 atcttatcca tttaataatc agatattttt aattttatta ttttcatatg caaaatcttc
    41761 aaagtcagaa attagtagtg gtttagaaaa aacataacct tgaatatagt cacatcccac
    41821 attttttaag aactcaactt gctctaattc ttcaattcct tcagcagtta ctttcatacc
    41881 tagccttttg ctaagttcaa taatagactt aataactacc ttaccacggt ctatattatt
    41941 tttgctgaca aagaacgaac ggtctaactt aattatatca actttaaaat cctttaatat
    42001 tcctaatgat gaatatccaa atccaaaatc gtctatagaa catttaaatc cattagaatg
    42061 aatatcatct attatatcta cagcttctgg attttctaag aaaatagatt cggtaagttc
    42121 taaatctatc agatatgttg gtacattgta tttattgcat ataagcttat atttttctaa
    42181 aaacaattta tcattcaaat gttgacgtga tacattaaca gaaattctca atacttcttt
    42241 accttctttt atccatttag aaatcaattt gcatgtttct tcaagtatat acaaatctaa
    42301 cttacatata aatccacttt tttcaaaaag aggaataaaa tcacttggat aaattatgcc
    42361 tttttccgaa tttttccaac gcacaagaga ctctgcacca ctaatttttc cactttttat
    42421 atcaatttta ggttgtaaac acataaaaaa ttctttattt tcaagggctt tttccattaa
    42481 atttgaaatt tccttttcag atattaatcg ttttctttct atatcactat aaaaagaaaa
    42541 atcactttga tgagctttat taaagctttt tcttgctgta tttgcatggt cttgtatcgt
    42601 aattaaatct tcattatgat tttcaattgt gtaaatacct gccgatattc ttaaaaagta
    42661 tggattttct ctatttttat taaaataatt tatatcagct tctattttat ataataactc
    42721 caaggcttct agcactggtc tattcttaat aagcaaatag aaaaggtctg catcatgacg
    42781 gcacacaaat tcttcatttt catcaatatt tttatataaa acattgtaaa gatgttttag
    42841 tgtcaaattt ccctttttac tgccaaaaca atcatttatt agcttaaaat cttttatatt
    42901 tatagctacc atcatgtaag tactatcagg tgattctaaa attaaaggtt ttactaagat
    42961 actgaattta gttgaattta taccatttgt tatactatct aaatatgcaa tattctctat
    43021 ttgatttaca tattttcttc ttataatata taaaatcaat gttataattc caataataca
    43081 tgtaattata aatgtcatta ttattgtaaa agagtttaac ttattaagtt caccaagtac
    43141 agcatcttca ggtactataa gaacaaaatg ccaatcattt aaaccttttg taattggata
    43201 ataggttaat aggcattgta caccttttga tgaagttatt gtaatatttc ctgatttatc
    43261 atttttaaaa tcattaagca tcttttgtgc ccaaggttca tctccagaac tcttatattt
    43321 atggccaagg tcttttatta attcagtatt tttccctatg aaaagaggtc ttccctgact
    43381 gttaataatt tcaatagttc cttctccatt aaagttatct atattaagaa tctcgtccat
    43441 actttcttta ttagatacac ctatcaaaat actagacact tcatgattat cattgaatat
    43501 aggtacacta tagaaaacaa aacccattga ctctattact tctgagtatt ctttaccttc
    43561 aattcctttt ttgtaggaat cagtattctt taaatcaaac ttttttccgc ttaaaaattc
    43621 agctttaccc tctaaatcta ttattcctat atcataatac ttgtaactag tctttctttt
    43681 agataaatac tcatatcgac tatcaccttc atattgctta ataaaatctg ccattattct
    43741 taaatcggat aaaataaatt tgattttaga atcaacattc attacaatct gtgtagatac
    43801 atcatttaaa tagtttttag attgtttact agatatattg tgtagtttta cagtattaaa
    43861 aacagtaatt acaaggattg aaataataag tgaacataaa attatagaca gaactaaact
    43921 atttttctta taccttgata atttcatttt tttcctccaa attataaacc tattttttaa
    43981 tgtatattga cacttacaaa tttttttact aagaaccctt cacactatat tatattatag
    44041 tattccattt attaatattc aataatacaa tcttaacatt tcattaatat ttcatatata
    44101 ataattttat taaataatta tattatatgt aatttttaat atttattgat taaaaacatt
    44161 atgacatgtc atatatcaat aaagaactat acctaaattt ggtatagttc tttattttaa
    44221 taacaccttc gatattctat aaaaaatcta ttacaatagc tactgcttat ctcctctaat
    44281 aatatggcaa ttatatcata atctatagta ttagatagta ttgattttga aatgatgtgt
    44341 ccacctatcc aaacatcatt tctaattttt taacttgagt agttgtagtt ttacaaaact
    44401 taaatctatc atccattttt tatacaaata gctcttattc ttactacagc aaatataaaa
    44461 taaactatat ttgtattaca atttatcatt gtatcatttt ttatttattt ttaaatttta
    44521 tccgaaaaat ttagattgcc cttgcatata acaccatgtc aggatatatc atccacttag
    44581 agaggtgaaa tataaatgat aataaataac tatcaaaatc aaagtatcat cacaaatcct
    44641 aaaaaatttg aaaatgaata tcaatattta ccagatactc caattgaatt attaaaagtg
    44701 gttcaaaacc taataattca tggagaccaa ggaaaactat acggtatatc ctttaataag
    44761 caacaatctg atgaagaatt gcttcgtaca gttcctcaaa tgttaaaaag aatatttgaa
    44821 ataaattcta actcactaac tattccaaga accccaaaac aaagacttgt tggaatgtgc
    44881 agagattatt ctttacttct tgtgtccttc ctaagatatc gaggttttga agctagaatg
    44941 agagcaggtt ttgctaatta ttttgaaagt gaacttactt atgaagacca ctggcttgta
    45001 gaatactatg atactgcaac aaagagatgg ataaaaatag atgcacaaat agatgacatc
    45061 caaaaaaatt attttcaaat taattttgac gctcatgatg tcagaagaat agatggcttt
    45121 ttaactggtt cagaagcttg gataaaatgt cgacaagagc atactcatcc agatgacttt
    45181 ggatataata aaaattggaa aggttggcat tctgtaaagg gtaatcttct acatgacttt
    45241 aataatatga ttggtttgga attacttcca tgggatttat ggacagaatt aagttccaaa
    45301 aaatacaatc aattaacaag agcagaaaaa aatttattag atgaaatggc agagatatta
    45361 tcaagcggaa ataaaaaaat agaagacctt aatttgttaa tagaaaaatt gcctgaagat
    45421 tatttgaaat caatcttttc tcagttaaaa atattaggta tttcggaaat aaaagaatta
    45481 gctaatcctc ttgaactaga aaagaaattc aaatttacaa aagcaataaa taaaccaatt
    45541 aaaaattcac tttgtcataa taaaagctct atctatttaa aaggaggaag acaaaacaat
    45601 ttaaaagatg ttgaagttac aattccaaag aataaaataa ctgtgattac aggtgtaagt
    45661 ggtagtggaa aatcttcttt agctttcgac acgatttacg aagaaggaaa aagacgttat
    45721 tttgaaaatc taggtaatgg agcaaaactt tcagaacagc ttcaaaaacc ggaatttgat
    45781 ttacttcagg gattaacccc tactatagct atcgaacaga aaaaaggaaa ccaaaatcct
    45841 cgttctactg ttggtactct tacaagcatt tgggactact taagaatgtt atttgtatca
    45901 atcggaaaaa gttactgtcc atattgcaaa actccattag aaaaaaagaa taatacaaaa
    45961 aattattgtc cacattgcca aactattttt tctaagataa atacttcaac cttcaatgct
    46021 aactcccata ctggagcttg tcacgattgt aatggattgg gttttaccta tcaagttaat
    46081 cctcaattaa ttgtaaaaga cccaactatt tcaatattag atggagctac ttactatttt
    46141 ggaaaattga gggggaaaaa gccaaatggt aattggatgg taggtgaatt atatgcaata
    46201 gcaaaagata aaaatataga cctagatata ccttggaatg aattgccaag agattttata
    46261 gatgcaatct tatatggtac agacgataag atatacgaat ttagttttga atcaagggga
    46321 cgagaatcaa agattagaag acctgcttca ggagcaatca accacattca aagacttttt
    46381 agagaatcta gttctgaaaa taataccctg catcaatata tgaacaaaat tccttgcaat
    46441 acatgtggtg gcgaattgct gtgcattgaa gctaggttca ctacaatcaa aggttatcgc
    46501 ttccctgaac taacaaaaat gacgatagaa cagttatgga attggttgtg tgaattgaca
    46561 aatcaacttc aacaaaagga gctatcttta gtaaatgata tattgacaga attaaaaatt
    46621 cgagttagtt atctattaaa ggtaggtctt agttatttat caacagatag aacagctcca
    46681 accttatctg gaggagaact acaaagagta cgattatcaa gtcagctagg aagtgaatta
    46741 gtaggattaa cctatatttt agacgaacca tctattggtt tacacccaag agaccataat
    46801 ctaatcatca aaatgataga agaattaaga gataagggta atactgttat agtagtggaa
    46861 catgataagg atacaatact gtctgctgat tatattattg atgtaggccc aaatgctggt
    46921 ataaaagggg gcttcatcat tgcagaaggt acaacccaag aaattataaa aaatccaaat
    46981 tctataacag gcaaatattt gagtacatac aataagataa gttcacaaaa taaaattata
    47041 ccaagtaaat ggttaagctt aaagggatgc catgcaaata acttaaaaaa tattgatgta
    47101 gaaattccct taaactgtat gtgctctatt acaggtgtta gtggttctgg taagagttct
    47161 cttgtatttc acagtttact tcctgctcta gaagaaaaat taaaacaaaa atctatccca
    47221 aataaaaatt atactgaact tactggattt gatgctattg atgattttat cttaatggac
    47281 caaacagcta ttggaaaatc tagccgttct acacctgcta catatatcaa tatttttgat
    47341 gaaattcgtt ctctatttgc tgaaactcca caagcaaaac aaaaattatt ggatgaaagc
    47401 tattttagct ttaatagcaa aaaggggcaa tgcccaaact gtcaaggatt aggtaaaaca
    47461 aaaattattc tacaatatat agcagaccaa tgggtaactt gtaataaatg tcaaggtaag
    47521 agatataaaa aagaaatact gtctatacaa tacaagggaa aagcaattgc agatatactt
    47581 gacatggaag tagcagaagc aaaaacattt tttagtgatt gctctgatat atatagaaaa
    47641 ctctacttat tagatgaagt gggacttggc tatctaaagc ttggacaaaa tacattagga
    47701 ttaagtggag gagaatctca aaggataaaa ttagcaaaag aattgggaac aaaaactaaa
    47761 aaacgaatgt tatacatatt agatgaacct actactggac ttcattttaa agatatagaa
    47821 aatttgttaa ttacttttag aaaacttgta aatgagcaac attcactttt aattattgaa
    47881 cacaacacag aggttatacg tgcttctgat tggattatcg atataggtcc agacagtgga
    47941 atgaatggag gggaaattgt cgcttctgga actcctgatg aaataaaagt aaatccaaat
    48001 agtattactg gacattttat ataaaaacaa ctaaataaac atggacttag acataaaatt
    48061 atagaatatc ttatattatg gaagaattat tataatagta gtataataaa aaaattaact
    48121 ttagtatatt gtttgtgata aaatatgaat aatctataaa atagagtata agaattatta
    48181 tgttttataa tagagaaagg aaaatcaaat gagttggaaa catataaaaa taccaaatgg
    48241 agatacaatg attttttgta actcatttat tactagcaaa ttatctatga atattattgt
    48301 tacacacact cctattgtca ctacgcttga gatgcaaaaa gcatacgaac catttactaa
    48361 atataatgta aatatatttg cttttgattt ttcaggaaca ggaaaaagtg atggatatga
    48421 aaaagatttt tctcgcaatt caattataaa agacttagat tctatcatta catacataga
    48481 aaaaaattat tcttccaaca tacatctata tgggaataca gggattggtg gcatgtttgc
    48541 gcaatattat gcatgttcag acaataagtt aaaaagtttt gctcagtttg cttgtgttga
    48601 ttataaaaac acaacaggag taggctatcc ctatctcact gttaaattat taaacctttt
    48661 ctttaagttt cttcctaatt ttcacataac agtaaaacca cctaaatata aaggttataa
    48721 tgaagtctat gataatgaat tttataaaat atttgaagag aaaaatcctc atatttggaa
    48781 aaatagtaca aagataatta atacaatgtt agagtgcttt attgcagaag atagtaagat
    48841 aaaagatgga gtcaacatac ctactcttgt ctttaaaaca cttcatgata gatattttaa
    48901 aacccaatat tttgatagct attataattc attaaaatgt aaaaagaagc ttgttgaaat
    48961 taataatgtt cataatagtt actatataga tagtgagaaa ttttgccaag aagcttatga
    49021 ttggtttgta gaaaaccagt gatataatct aaatgttata tggatttctg attatctttt
    49081 cagaatttat taaaaatcca aatagcctta ctttattggc tatttggatt taagatataa
    49141 aaaaatagat atcctttact tatcaaaaac ttataaataa aaaaatattc ccagtatacc
    49201 acttattatt ataatgacaa taggattaat tttccactta cgtactatca gtagcgtaac
    49261 aaaaaagatt attagtgcag tccagtttag catctcaaat atagaattga agtacacttt
    49321 attcgtacca aataatgcaa ggattataat tgtagccgca gctgagataa ttaaacctaa
    49381 tgaagctgat tttagaccat ttaatatttc aaatatataa gtagagttct gatgcttttg
    49441 aaaaaaatta tataaaaata gagatattac tacaccacat aatacacaac ctaaagtggc
    49501 tgcaactgct ccccaaaacc ctccaatttg aagcccaaca aaagtagaag tattaacagc
    49561 caatggtcct ggtgtcattt gcgaaatagt tataatatct gtaaacattt tctcacttat
    49621 ccatccagtt tgatttacta ctttctcttg gattaaaggt atgattgcat agccaccacc
    49681 aatactaaac aagcctattt ttaaaaatat aaaaaataag ttccaaattg tattcattta
    49741 tttttcctct tcttgtagaa aacttgcatt acacatacac aacagcaaac agataatata
    49801 aaaattacat ttatactcat cacaaagttt gcaaagaaag caataggtat catagctgat
    49861 aaaaatagag aacgttgttt taatatcata gagcacatgt caataatcaa atccacaatt
    49921 agtgcagcaa caccagcttg cattcctttt aatactgcag ttacaatagc attagatata
    49981 aaagtggtgt aaaatgctga tactaatcca agaataacga gtggaggtat tatagctgct
    50041 atacaactaa tgacaacccc taaagtacca gctactcgat aacctgccaa agcagataaa
    50101 ttaattgcaa tagctccagg agttgattgt gcaactgctg ccatactcat caaatcatct
    50161 tctgtaaaga aatgcttttg atttacaaaa taacgtctaa tcataggtac aactacatac
    50221 cctccaccaa aagtgaatgt gctaataaac aagttaataa ttaaaagcca aaaatatgtt
    50281 tttctgcttt gattcaaaat attcctcctt cttttcactt catattattc agtatacctg
    50341 ttgctttgca atctgtaaaa tgatagaatt taatggaatt aatcaatttt attcatgtct
    50401 agtgaggata tttattatga taaacatacg atatttagag attttagaag caattgaaca
    50461 aacaggtact tttacaggtg ctgcaaaaaa attacatatc acacaatctg ctgtatctca
    50521 tgctatagct gaacttgaac aacaagctga aacatcatta tttgacagat taccacgagg
    50581 ggtatgtctt actcgctgtg gcatttctct tttagaagaa gcacgcagta tcttaactgc
    50641 ttgtcgcaat ttagacaaaa gaatcagtcg tttagaggaa tgtacaccta taaacattgt
    50701 ttctagcatt acaattgcct cttttttact tccaccaatt ttaagtcgac taaaaaattt
    50761 gttcccatct cttaaagtga atgtacgtgt cgaaagtgct aattcagcca tggatatttt
    50821 aaaaagtgga gaagctgata tatgtttttg ggaaggtata gaaccacagg gggcattccg
    50881 tacaatttta ttaggttcct ataagttatg tgttgcatgt gctccaactt ttcctttatc
    50941 tgaacaaacc ttatctctac gacagttatg cacgtttccg ttattgttac gtgagcaagg
    51001 aagtgctatt cgcgatactt tagacagtgt attatctctt tcaaaccaaa aggcttatcc
    51061 tatttgggaa agtgttaatt cttttgcact tattaaagct gcagaagcag ggttaggtat
    51121 aaccattttg ccagagaatt tattattaga ttcactctta cataaaaaat tgcgattgat
    51181 tgaattagat gggatagata tggaaaataa aatgttggca atattacata aggataaaaa
    51241 tattacacaa cctttgaaaa taatattaga taatataagc aatgtacttt aatttaaaga
    51301 tttaattttt taacattcta ttttttagca taaaaagtgt gtactattcc ttaatgttgt
    51361 gattttaatt ataatcactt tttaaaataa tacacacttt attttaagta caatctaaac
    51421 ttaaataaga taaaagtttc tattgtatat gttttaaatt aatactatat tcttgtttac
    51481 ctttttcaat tttaaattta tcatttttat taggataaat agttacaaca ttatctttat
    51541 actctgattc atcacatttt atattaattg gcataacttc agcttcacca tatacatagc
    51601 taacaggctt attattattc attacaacaa tctgcaccat gtcatcaccc tttggagatg
    51661 atatatttct ccatttatat cctattgttt tatatatatc atctgcagat gttccagatt
    51721 taaaaacata tattttatcc cattcaggag tctttacttc tgataatcgt atttctttct
    51781 tatctttact tactttatta attgaagaaa taaattctcc aaatttgtca ctttcttgat
    51841 ttttttcaaa tttaatcaat ttactagatt tgtcaactat attccattta tcattggttt
    51901 tttctaattt aaaattaatc ttagaaatac attctccatg ttttcctggc tcagtgacta
    51961 taacattttc tcctgattta tttttataat catgttgctc aatttgaaca tgattatgac
    52021 ctgcaactat agcatcaatt ccatcaactt gttgagctaa atcttgtatt ctatttcctg
    52081 ggtttctagg cttcttaggt ttctcacctg tatgtgccac agcaactata atgtcaggct
    52141 tctctttttc cattatacta acccactttt tagcatcttc tactaaatca ttcatataca
    52201 attcaccatt gtagccctct tggtctttta gttctaaaga cttagagtca acaagttttc
    52261 catctttcca ctgtttcctc tcaccaactt cttttatagt aagccctaaa attcctagtt
    52321 ttacgtttcc ttcaggtgta ttaatatttt ttattatgta tggttttgta taactgtctc
    52381 catttttttt gtaagtattt gctgataaaa tatttatttt ttgcttctca aaatcagata
    52441 tcatattatc cagataaaat ttattgttgg atataaattc atgattccca agaactgcaa
    52501 catcataacc tacctctttc atatcttttg aaataggcgt ctcaatgtaa cgctcagtgt
    52561 tactatcaat atccttattc ctagcactaa aataactatc catgctagaa ccagatactt
    52621 ccccactctg aacctcccat gactaaagtc acagggttcc tgcttcatag aattttgcat
    52681 actaaaatat gtcttactaa ttctccacag gctatcccca tagttcctac ggttcttaca
    52741 taagttattt attttgaatt gttattagtc ttaatccttc ttttagtata tttatacttg
    52801 catttatatc tctatcgtga gtttcattac aactaggaca aatccattct cttatattta
    52861 agttcttaac ttcctcgttt ttatacccac atttattaca tatttgtgaa cttgcaaaga
    52921 atttacctac ctttacaatt tgtctatcat accaattagc cttgtattct aattgacgaa
    52981 taaactctga ccatgacaca tctgaaatta agcgagatag tttatgattt ctaatcatat
    53041 tctttacttg taaatctt
//
LOCUS       DAMKOJ010000019        53032 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.020, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000019 DAMKOJ010000000
VERSION     DAMKOJ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53032
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.020"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            212..1288
                     /locus_tag="PC592_001227"
     CDS             212..1288
                     /locus_tag="PC592_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF4055221.1"
                     /translation="MKTQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1391..2233)
                     /locus_tag="PC592_001228"
     CDS             complement(1391..2233)
                     /locus_tag="PC592_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF4055222.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNKTFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKIEVIDSLSGSIGIGQLVLKAAILIEEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEVGSVMGTYTSKGAIL
                     ITAI"
     gene            2417..2989
                     /locus_tag="PC592_001229"
     CDS             2417..2989
                     /locus_tag="PC592_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4055223.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKNDIIYDIADTHLEVITSAILNCVKNVKSKNSQIDMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERMRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLINHWI"
     gene            complement(3152..3424)
                     /locus_tag="PC592_001230"
     CDS             complement(3152..3424)
                     /locus_tag="PC592_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055224.1"
                     /translation="MLRERFVVRNHHNPHTSECCGTGGKGCCGGDNNEHSHQHSHSHG
                     HEHEHINGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDEHTHEHK"
     gene            complement(3538..4410)
                     /locus_tag="PC592_001231"
     CDS             complement(3538..4410)
                     /locus_tag="PC592_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF4055225.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIVAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4697..7804)
                     /locus_tag="PC592_001232"
     CDS             complement(4697..7804)
                     /locus_tag="PC592_001232"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDF4055226.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEIYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAERAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVVKK"
     misc_binding    complement(7896..8128)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8303..8830)
                     /locus_tag="PC592_001233"
     CDS             complement(8303..8830)
                     /locus_tag="PC592_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDF4055227.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCKENTA
                     LREKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8865..9650)
                     /locus_tag="PC592_001234"
     CDS             complement(8865..9650)
                     /locus_tag="PC592_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDF4055228.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITRKGKIKVQARLIV"
     gene            complement(9660..9917)
                     /locus_tag="PC592_001235"
     CDS             complement(9660..9917)
                     /locus_tag="PC592_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDF4055229.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9936..10394)
                     /locus_tag="PC592_001236"
     CDS             complement(9936..10394)
                     /locus_tag="PC592_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDF4055230.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10433..11137)
                     /locus_tag="PC592_001237"
     CDS             complement(10433..11137)
                     /locus_tag="PC592_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDF4055231.1"
                     /translation="MGSIKDNLSEIRSKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGNKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYDKK"
     gene            complement(11147..11782)
                     /locus_tag="PC592_001238"
     CDS             complement(11147..11782)
                     /locus_tag="PC592_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055232.1"
                     /translation="MKKVKYTRLVILGIFIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGAIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYREQKIDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVINEQSQSV
                     KFVILEGITYENESSVFVDYYKNDLNGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12162..13202
                     /locus_tag="PC592_001239"
     CDS             12162..13202
                     /locus_tag="PC592_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4055233.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13658..15013)
                     /locus_tag="PC592_001240"
     CDS             complement(13658..15013)
                     /locus_tag="PC592_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HDF4055234.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDESDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VREMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLNVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15039..15308)
                     /locus_tag="PC592_001241"
     CDS             complement(15039..15308)
                     /locus_tag="PC592_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF4055235.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15598..17559)
                     /locus_tag="PC592_001242"
     CDS             complement(15598..17559)
                     /locus_tag="PC592_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055236.1"
                     /translation="MKKYEIFIFISIVVLCFISFPYKVFGQEENCLEDFERWVQENKN
                     NKEKIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHVENGGSISIGINNIIATDGTALYVEEGGDLYIKSSYESVEKIKANGKDAI
                     GIYTENDIRIINKDIEVTGERAIGVYSKGDVEIEESSIKAYSNNNENELLRDNNKLVQ
                     SIISESKKVYIIDSYNELIPSIAEDSGYNIVKCCYRGIGVFSEEIKVSKDDKIENIKF
                     PQYMVLETSSGNQLDIDVEWDFTDYYEKLEKGEKFNITGKFKTETLNKEKIIINDDVV
                     PILNIYVMDKKPIDNLELEFQNTKKGYVAALFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRIRVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEQEND
                     DIDGDRGGGGRDDPDRDKDDNSQNGNNGNDNNDSNNNQNNNNENDNSDEKQPNAPKDD
                     VESSTGSNENKNPQGDIPKEGNIPKDGNKENNSDKEKGVFNKSSIIENDGDYDLNLKS
                     IFGINEHSFPYRESISNKNQDTNKNKSNISDYNGIINNNYKLESKEYNLKKDIIFLAC
                     ILTPIMIGSILIVNSDTRKSIIKFIKEKK"
     gene            complement(17742..19217)
                     /gene="spoIVA"
                     /locus_tag="PC592_001243"
     CDS             complement(17742..19217)
                     /gene="spoIVA"
                     /locus_tag="PC592_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HDF4055237.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIMQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19307..19483)
                     /locus_tag="PC592_001244"
     CDS             complement(19307..19483)
                     /locus_tag="PC592_001244"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055238.1"
                     /translation="MYIKFFNCICSGIDRTAQLHLDSNTRILQRGDIVIHSRQVWYEN
                     YRAENERISICKRN"
     gene            complement(19496..19678)
                     /locus_tag="PC592_001245"
     CDS             complement(19496..19678)
                     /locus_tag="PC592_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I V"
                     /protein_id="HDF4055239.1"
                     /translation="MFCYINPKGTTVGIEKHIVSASFSEYMTDKSFVIKDVGSKIFEM
                     RYVKDVGDNALLKYVS"
     gene            19688..19960
                     /locus_tag="PC592_001246"
     CDS             19688..19960
                     /locus_tag="PC592_001246"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055240.1"
                     /translation="MFPEDLGVHDSDISLMITGESIKERNKILLNNLVDTGYIPAKDL
                     DIINDIIISFYQNLLFLKKNTGKNSDDDELTMKTISSIEYIIKHAK"
     gene            complement(20116..21135)
                     /locus_tag="PC592_001247"
     CDS             complement(20116..21135)
                     /locus_tag="PC592_001247"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF4055241.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIILAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTWLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(21166..21780)
                     /gene="plsY"
                     /locus_tag="PC592_001248"
     CDS             complement(21166..21780)
                     /gene="plsY"
                     /locus_tag="PC592_001248"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDF4055242.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVVITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(21814..23133)
                     /gene="der"
                     /locus_tag="PC592_001249"
     CDS             complement(21814..23133)
                     /gene="der"
                     /locus_tag="PC592_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDF4055243.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKELTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(23167..24495)
                     /locus_tag="PC592_001250"
     CDS             complement(23167..24495)
                     /locus_tag="PC592_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HDF4055244.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLEVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNGKSASKTIEQIHQMQQKYLKQLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEDILKRDKKVSIATG
                     HSAYEFIQSMANAMMDKFKNLQINVYEIKNKFFGETITVSGLLTAKDLKEQLENKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMKIKIIPCLNEGKDFVDKILK"
     gene            complement(24731..24931)
                     /locus_tag="PC592_001251"
     CDS             complement(24731..24931)
                     /locus_tag="PC592_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055245.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(24933..25865)
                     /locus_tag="PC592_001252"
     CDS             complement(24933..25865)
                     /locus_tag="PC592_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF4055246.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLISQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLLLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(25911..26843)
                     /locus_tag="PC592_001253"
     CDS             complement(25911..26843)
                     /locus_tag="PC592_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF4055247.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYDLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNDVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKRTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(26898..28187)
                     /locus_tag="PC592_001254"
     CDS             complement(26898..28187)
                     /locus_tag="PC592_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4055248.1"
                     /translation="MEDLNSVYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLKSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILRFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(28216..28908)
                     /locus_tag="PC592_001255"
     CDS             complement(28216..28908)
                     /locus_tag="PC592_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055249.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(28923..29684)
                     /gene="pgeF"
                     /locus_tag="PC592_001256"
     CDS             complement(28923..29684)
                     /gene="pgeF"
                     /locus_tag="PC592_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDF4055250.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCKEIDEKLKSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLICSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(29681..30142)
                     /gene="nrdR"
                     /locus_tag="PC592_001257"
     CDS             complement(29681..30142)
                     /gene="nrdR"
                     /locus_tag="PC592_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDF4055251.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIEEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKDLDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(30164..30427)
                     /locus_tag="PC592_001258"
     CDS             complement(30164..30427)
                     /locus_tag="PC592_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF4055252.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(30531..31304)
                     /gene="sigG"
                     /locus_tag="PC592_001259"
     CDS             complement(30531..31304)
                     /gene="sigG"
                     /locus_tag="PC592_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HDF4055253.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(31396..32118)
                     /gene="sigE"
                     /locus_tag="PC592_001260"
     CDS             complement(31396..32118)
                     /gene="sigE"
                     /locus_tag="PC592_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HDF4055254.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(32143..33015)
                     /locus_tag="PC592_001261"
     CDS             complement(32143..33015)
                     /locus_tag="PC592_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HDF4055255.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTIPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     KLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(33314..34588)
                     /locus_tag="PC592_001262"
     CDS             complement(33314..34588)
                     /locus_tag="PC592_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF4055256.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGGIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEVPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(34873..36030)
                     /gene="ftsZ"
                     /locus_tag="PC592_001263"
     CDS             complement(34873..36030)
                     /gene="ftsZ"
                     /locus_tag="PC592_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDF4055257.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLETKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(36220..36573)
                     /locus_tag="PC592_001264"
     CDS             complement(36220..36573)
                     /locus_tag="PC592_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HDF4055258.1"
                     /translation="MLWVLGGLAFGVVIGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGISLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(36672..37346)
                     /locus_tag="PC592_001265"
     CDS             complement(36672..37346)
                     /locus_tag="PC592_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF4055259.1"
                     /translation="MKKKIVILGAFILGIFISTYIKSLDPNRVYITLGQTENIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSSVTGPG
                     ITITMKDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFTK"
     gene            complement(37351..38049)
                     /locus_tag="PC592_001266"
     CDS             complement(37351..38049)
                     /locus_tag="PC592_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF4055260.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEISSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(38072..38812)
                     /locus_tag="PC592_001267"
     CDS             complement(38072..38812)
                     /locus_tag="PC592_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HDF4055261.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNINLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSVDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(39073..40299)
                     /gene="murG"
                     /locus_tag="PC592_001268"
     CDS             complement(39073..40299)
                     /gene="murG"
                     /locus_tag="PC592_001268"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF4055262.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDVVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEEKL
                     VFTGNPVRKEILLSRKNIARKNLSISEEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMESISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(40317..41447)
                     /gene="spoVE"
                     /locus_tag="PC592_001269"
     CDS             complement(40317..41447)
                     /gene="spoVE"
                     /locus_tag="PC592_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HDF4055263.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIERNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGVALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(41499..42854)
                     /locus_tag="PC592_001270"
     CDS             complement(41499..42854)
                     /locus_tag="PC592_001270"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDF4055264.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDIDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSNEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKTNIFMNQTSEDFCV
                     LNYDDEIVKGLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(42873..43841)
                     /locus_tag="PC592_001271"
     CDS             complement(42873..43841)
                     /locus_tag="PC592_001271"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDF4055265.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIVTVVLAWISIIAVF"
     gene            complement(43884..45257)
                     /locus_tag="PC592_001272"
     CDS             complement(43884..45257)
                     /locus_tag="PC592_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDF4055266.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGNISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLSKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     ANTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDIYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(45424..47403)
                     /locus_tag="PC592_001273"
     CDS             complement(45424..47403)
                     /locus_tag="PC592_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HDF4055267.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASKIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGIEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDVKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(47415..47762)
                     /locus_tag="PC592_001274"
     CDS             complement(47415..47762)
                     /locus_tag="PC592_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055268.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGTKCILLIATFAVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(48239..49174)
                     /gene="rsmH"
                     /locus_tag="PC592_001275"
     CDS             complement(48239..49174)
                     /gene="rsmH"
                     /locus_tag="PC592_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDF4055269.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAINTAKERLSEYEGRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKTIETTGELVDIIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKYLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEVEANPRSRSAKLRVAEKI"
     gene            complement(49204..49950)
                     /locus_tag="PC592_001276"
     CDS             complement(49204..49950)
                     /locus_tag="PC592_001276"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDF4055270.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKESKRVGIKEDD
                     VLNIAIIAIPAGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGLIAHIYLSKKNKNNISEE"
     gene            complement(50349..51635)
                     /locus_tag="PC592_001277"
     CDS             complement(50349..51635)
                     /locus_tag="PC592_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF4055271.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPLGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPKSVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINDNFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKKIILDYIEKSKKEGLSKEEFDRTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(51650..52915)
                     /locus_tag="PC592_001278"
     CDS             complement(51650..52915)
                     /locus_tag="PC592_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF4055272.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSISEFGYEDEIDSITSKELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIIDIPRADFIKNVDEVKVVDEQMEITQGKLVMGYRANVDYADTDRYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSILFISSGIETKDYDKAVEL
                     IKEQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFAFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
BASE COUNT        16404 a         9742 c         5529 g        21357 t
ORIGIN      
        1 cataacttta tagacttaat ttattacttt tatagaattt tcacaataaa aagtcatttt
       61 acttctgtat ttaatgcaaa aacagagatt aaacttaata taaaaaatat ataacaaaat
      121 ttttttatat ttctaaaaga aaagtatact cttttttgtt taataatgct aaaattgatt
      181 tgtattgaat tttgattagg aggaaattat tatgaaaact caaagattaa atgctgtact
      241 tgaacaaatg aaaaaagatg atatttctca aatgttagta agtgacccta cttcgatatt
      301 ttatcttaca ggggtactaa tccatccagg tgaaagatta ctagcattat acttaaattt
      361 aaatggcaat aataaattat ttataaatga attattccca gtttcagaag atttaggtgt
      421 tgaaatggtt tggtttaatg atactcaaaa tccagtagaa ataataactg aacatataga
      481 caaaaatgct actatgggtg ttgataaaaa ctggccagct agattcttat taaacttaat
      541 agaattaggt ggaggaagta agtttgtaaa ttcatcttat ataatagata ctttaagaat
      601 gtgtaaagat gaagaagaaa aagagttaat gagaatagct tcaaaattaa atgacaaggc
      661 tatggaacaa cttaaagcta ctgtttctgg tgaacttaca gagaaacaac ttgttggtaa
      721 attatctaaa atatatgaag acctaggtac tgatggattt tcatttgacc ctattatagg
      781 ttttggtcct aatggagcta atccacatgg tgaacctgga aatgcacttg tgaaaccagg
      841 agatgcaata atattagata taggttgtat aaaagataac tattgtgctg atatgacaag
      901 aactgtattc tataaagaaa tacctgaaaa aggtagagaa atatttgaaa tagttcttga
      961 agctaataag agagctgaag ccattgtaaa accaggagtt agattctgtg atatagatgc
     1021 agctgctcgt gattacataa ctgaaaaggg atatggacaa tactttactc atagaactgg
     1081 tcactctata gggcttgaag ttcatgataa aggagatgta tcttctataa atacagatac
     1141 tgtacaacca ggaatgatat tctctataga accaggtata tatttaccag gtgagtttgg
     1201 agttagaata gaagatttag tacttgttac tgaagatggt tgtgagatat taaacaaaca
     1261 cgacaaagaa atatgtgtag ttggttaatt ctaaaatcaa tttgataaaa ttaaaaaacc
     1321 atataaaaat gtttaaaaca tttttatatg gttttaattt ctcaatctat gatttatttc
     1381 aatccatcat ttatattgca gttattaata ttgcaccttt tgaagtatat gtacccatca
     1441 ctgaaccaac ttcacatatt acaacatctt tatattttac atccttttcc ataacttccc
     1501 ttaccttttg agccttttca gggcaattag catgtcctat aaataaaacc ttttcttctt
     1561 tatctttaat ttttgactct actaaagtaa tcagcttttt caaactattt ccttcgcctc
     1621 ttgccttatc tataggagtt acaacgccat ctgcaacttg tattatcgcc ttaaaattca
     1681 aggtatttat aatttttcct gctattggat ttatcctacc acccttaata gcattttcta
     1741 aagtttcaag agttccaaaa aatggaggat tatctttata tttatttatt attgaaacaa
     1801 tctcttcaat ttcttttcct tcttctatta atattgccgc ttttaacact aattgtccta
     1861 ttccaattga cccactaagt gaatctatga cctcaatttt cttgttattt ccttcttttt
     1921 caaacatatc ttttgctaaa agtgcactat tataagtccc agataatcct gaacttatat
     1981 taattaccaa tacactttct tcctgacaat ggtatgcttc taaaaattta tctggagaag
     2041 gacatgatgt ttttggtagt actttgctct cactcatttt tctatagaat gttttattat
     2101 ctatttcctt tccagatata taactttctt ctccaaaaga tacatttaaa ccaacaactt
     2161 ctatgttgta tttttctatt atatcatctg gtaagtcaca tgcactgtcc actatcaatt
     2221 ttattttatc catattaacc tcactataag atattatttt atttattcag tcggtcgtac
     2281 gaccgattta attattattt tatatattga atgaaaaaaa gtcaatagat atagattctc
     2341 cctttattga caataaatat tcataagctt ataatgttat taatttgtta taagtataca
     2401 tggagaggta ggttttatga aaacaaataa tatgaaacag gctattttat catctgcaac
     2461 taatttaata gccaaaaatg gagttcaaaa tactagcctt gctgatattg caaaagatgt
     2521 aaatataagt aaaggcactt tgtattatca ctacgcatct aaaaatgata ttatatatga
     2581 tattgcggat actcatttag aagttataac tagtgctata ctaaactgtg taaaaaatgt
     2641 caaatcaaaa aattctcaaa tagatatggt taacttaatc ttagagaaaa tctctactat
     2701 agaaagtcgt ggtagggtac atatgtatct tatttgtgag gcaattactt caaataatga
     2761 tttaaaagaa agaatgagat taaaatatat tgaatggaga actactctta aatctgaaat
     2821 tgttgaatca ctagaaaaat ataatagtag cgaaaatgaa caggatgctg aatcattttc
     2881 ttttttactc atgtcaatag ttgatggttt agttgtccaa agtttattaa aaacagaaaa
     2941 aataccttat gaaaatatag cttctttttt aattaatcat tggatttaaa tttaatactt
     3001 agataattaa taaaagtgaa ctatttaagt tatctactct aacagttcac tttcttattt
     3061 attatcaata aattttactt aaaaccttca atttttattt aaaccttcat ggaatcacaa
     3121 aataaaaatc tcttataaat ttaaaatgtt tttatttatg ttcatgtgta tgctcatctg
     3181 aatgttcatg accatgtgta tgtgtatgtt catggctatg ctcatgagta cctgaaaaac
     3241 catcatcatg attatggtcg tgacctacac catttatatg ctcatgttca tgaccatgac
     3301 tgtgagaatg ttgatgtgaa tgttcattgt tatctcctcc acagcatcct tttcctccag
     3361 tcccacaaca ttcacttgta tgtggattat gatgatttct tactacaaat ctctctctta
     3421 acataattct tatacctcct agtatattat tgagtacttc atgtactcca ttaattacag
     3481 tatacatcta actaggtata atctcaatac atatggtatt ttttaacatc tatagtatta
     3541 aagaaactta tccttaaaac ctccaccttt tacttcttca acattattga cagaaataaa
     3601 agcttcacta tccatatcat aaattaaatc tttaaattta cctatttcat ttgcagatat
     3661 tatgcaataa atcatctttt tcttattctg tgtatatgca ccttctgcct ctaaaaaagt
     3721 gactcctctt cccattttat tcattattac tttagatatt tcatcatatt tatttgaaat
     3781 taaaagtatg gatttttttc tatcaaagca atcttttcct atatccatag taaaagaaat
     3841 tatatacatt gtaattaaag tgtacatcac caatttagct ccaaataaga aagcccctgc
     3901 acatactaca aaaaaattaa taaataaaaa tgtatttttc ataggtatat catactttct
     3961 tttcattata gctgctacta tatcaagtcc tccagcagta gctcttgctt taaaagtcaa
     4021 tcccatgcct ataccagtta atgcaccacc ataaatacac tgtagcatag tatcatctat
     4081 cgggaaatat ttagcaatat cttgtgttaa cccaagtgct aaagaaaata gtaacatatt
     4141 gacaaaactt atcaataaaa acttattatc aaaatacttt ctagctataa taaatattgg
     4201 tatgttcatc aagaaacttg atattccctg atttatgcca aacaatttat ataatataac
     4261 acaaattcca gctactcctc cacttaataa tttggctggt gctagatata aatttattcc
     4321 taaggttgat agaatcatac ccaatataat aagacaatat tgtaaaaata tgttattatc
     4381 aatacttagt tttttgcttt caccatacat caaaacgcac ccctttgcat aataaataaa
     4441 ctaccctgca aaacacacga taaatttata aataaattta tcagaagtag cttactaaaa
     4501 atattattca tcctcactta aacgtttatt cattaatatt ctatcacatg atatgaataa
     4561 tttatatgat ttatatagaa ttatttattg taaattttgg aatattaaaa cattttagtg
     4621 aatagataat tatattacac aaaaaatccc tatagaaatc tataaactaa tttctatagg
     4681 gattttgatt aactaactat ttttttacaa cttttatacc tgtcatatgg tcgtttaagt
     4741 tttgttcttc taaagattta tcatctactc tgtttatttc taaagctaaa gtttcagact
     4801 tgatgtattc attaaaatgg tcaacagcct tagcaatttc gtcatcacca cagtattcta
     4861 ttactatatt atctaatact tcaaagttat tagattttct caattgctgt actttagata
     4921 taaattctct agcataacct tcattaatca actcttcagt tagcttagta tctagtataa
     4981 caaaaagatt gttttcaaca gatacattaa atccttcctt agcagttata cctattaata
     5041 ctaaatcctt attaaattca aaagcttcac catctaaatc aactgttaga gtctcacctt
     5101 tttcaagttt attagcagtt tcatgagcat ttaatttact taaagctcca acgaataaat
     5161 tcatcttaga acctaataat ggtcctgctt ccttaaagtt tggttttaaa ctaaagttca
     5221 tatactcatc taaatcctta gcaaagatta cctctttaac attaagctct tcttttatta
     5281 aatcaactac atcgcttatt gtatcttcaa acttaccatc tactaaaact ttttgtaatg
     5341 gttgacgaac ttttattctt tcaacttctc ttgaagctct acctaaagta actaagtttt
     5401 tagctaaatc cattttttct tctaatttag tatccactaa ctcttcatta cacttaggat
     5461 attcagctaa atgaacagat acttctcctg ttaagtttct atacatttcc tctgacatat
     5521 atggtgcaaa tggagctata gctctacaaa gaccatgtaa caattcataa gttgtgttgt
     5581 acactgcttt cttatcttct gttaattcag ttgcccagaa tcttcttctt gaacgtctta
     5641 tataccagtt agataaatca tcatttataa aatcttgtat cattcttaaa gttttattta
     5701 actcaaatat agctaaattt tcttctacat ctttcattaa attattgaat ttagataata
     5761 tccatctatc aagttctggt ctatctttat attctacaaa aaattcagtt ggatttatat
     5821 catctgtatt tgcatataaa gtaaagaaat tatatacatt cttcatagta cctataaatt
     5881 tactttggat ttcttttaat ccatccatat caaatttagt tggagtccat ggtggagaaa
     5941 catatagtaa ataccatctt aatgcatctg ctccatattg gtcaaataat tccattggat
     6001 ttactgtgtt tcctcttgat ttactcattt tcttaccatc tttatcaagt acaaggtctg
     6061 gaactaaaac actcttatat ggtgctttcc ctaatacaaa tgttgatact gcaagtaatg
     6121 agtagaacca tcctctagtc tggtctatac cttctgatat ataatcagct gggaatagtt
     6181 ggtcaaagtt ttccttattt tcaaatggat agtggtgttg agcaaatggc atagccccac
     6241 tatcaaacca acagtctata acttctgtta ctcttgtcat tggttttcca catttttcac
     6301 attttaagtg tatatcatct acatatggtc tatgaagttc aactgtttct ggatttacat
     6361 cttctatagc tctttcagct aattcagctc ttgaaccaac tgaatctgta tgaccacatt
     6421 cacatctcca tataggaagt ggagttcccc aatatctagt tcttgatatt gcccagtcat
     6481 ttagattttc tagccagttt ccaaatctct tctctcctac aaaacttggg aaccatttta
     6541 caccattatt attttctatt aatttgtctt taagtttagt catctctata taccagcttg
     6601 gttttgcata gtatactaat ggagtttgac atctccagca gtgtggataa ttatgaacta
     6661 ctttttcttt gctatataat ttattttcag aagctagcca ttttattatt tcaacatcta
     6721 gcccatcttc cattacaaat ctaccttccc aaggagtaga tgtaaattta ccagtttcat
     6781 ctactggttg aataactggt aaatcatatc ttttacctgt gttgtagtca tcttcaccaa
     6841 atgctggtgc tgtatgaact ataccagtac catcttcagt agttacataa tctcctactg
     6901 taataaaaaa tgcttttttg tcaacttcta caaaaggcat taattgttca tattccaaac
     6961 cttctaggtc tttacctttc atttcttcta aaacttcata atcctcacct agtactttat
     7021 cagctaaagg tttagataca taatatatct catcaccttt tttaactttt aaataatcta
     7081 catcagcatt tactgttaac gaaacatttg atggtaaagt ccatggagtt gttgtccatg
     7141 ctaagaaata ttcatcagca tcttttttct taaatttagc tataactgta ttagttttta
     7201 cttctttata tccttgtgca acctcatgac tagcaagacc agttccacat cttggacaat
     7261 aaggaagtat tttgtgacct tcatagatat atccttcttt gttgaattta ttcagtatcc
     7321 accatacaga ctctatatag ttattatcta aagttatata tggattgtct aaatcaactt
     7381 cataagccat tctctcagtc attattctcc attgtttttc aaatgagaaa actgattctc
     7441 tacatttttg gttaaattca gctattccat actcctctat ttgttgttta ctagtaagac
     7501 ctaattcttt ttctacttgt atttcaactg gtaatccatg tgtatcccaa ccagcttttc
     7561 tttttacttg ataaccagac attgttttat atctacaaac tgaatcttta agtgttctag
     7621 ataaaacatg gtgtactcca ggatttccat tagctgttgg aggtccctca taaaatacga
     7681 aacttgggtc atctttccct ttttctaaag ttttttcaag tatatttata tctttccaat
     7741 aatcaaaaac ttgtgcttct gcttgtttta cagaactgtc taccaatggc ttaaatttcg
     7801 ccatgtaaat caccctttcc tataaatatt ataattccaa aattttttat tctttcacat
     7861 aaatttaaat actaaaaaac tcgccccctt taaaccaaag ggacgagtta taaatcgcgt
     7921 taccacccta attctatatg taaactaaat actagctaca tataacactc taatagtata
     7981 acggtactaa ccggcacagc ttagtagaat ttaatcgttc agcctgcagc tcaagagtga
     8041 tttttacctt tataaattca ttggttctca gcatacccaa ttctctgtaa aattatctaa
     8101 agataaacgt ctctatcaac gcttttaaaa atttatctgt gtttatatga aattctataa
     8161 caaataattt gaatagtcaa tatatttttg aaaaatataa taatttctat ttttcttaca
     8221 tttttatcct atttttaatt tttgttatag atttctcaaa cttacacaat gattctacat
     8281 aacaaataac caaattacaa gcttattcta aagttgtagc agcttcatca ttactataat
     8341 tatacactgt tgttccttca aatgcattta cacatttttc atctacatca taaaaaatct
     8401 catctacact tcttatttca tcttctaaca atgatttgaa tttatttcta aatatcttaa
     8461 attctttgac taaagcatca tactcttttc ttatctctat aacacggtta ttagcttgtt
     8521 ctataatttg tctagctttt aaatcagctt cttcaacaat tatcttagcc tttttattag
     8581 ccgcgctaca agtgtcttct gctgcacttt gagcagttat taaagtagct tttagtgttt
     8641 cttcaatatt ttcatactta tttacttggt cttgatataa ccctaatttt tctctaagag
     8701 ctgtattttc cttacataga gactcataat cttccttgat gatatctaaa aattcatcca
     8761 cctcttcatc tctatatcct cttaaacctt ttttaaactc tttattttct atctcaattg
     8821 gagttagcat tacatttcct cccagctata atttaaatta gtccttatac aattaatctt
     8881 gcttgaactt ttatttttcc ttttctagta atatctccta tttgtgttac cttagctctt
     8941 cctttacctc taatagaaat caaatcatca ttttttacta ttttagaagt tgaagttatc
     9001 ttttcataat tgacatggac tttttctcca tttatgtatt ttgcactatc ttgtctagat
     9061 atattgtaaa taccacttat cacacaatct agcctatctg aagatactgt aaatgacact
     9121 tctttatatt ttgaagaact attaacaata ttttctctgg aaatttcctt tacaattaca
     9181 ttatttcttg aaactttttc taagtttaca attataaaat cgcaaatatc actacttaca
     9241 actacttgac aaaagctatc atgtataatt atatctccaa ttttttctct ttttatacct
     9301 agacctagta ttgaccctaa gtaatcttta tgagatatat ttttaaattt aaaattccct
     9361 tctatttgta aaaatctaag agtatcttct atatcttcat attccatgta aaatggataa
     9421 ataaatacag tgcttctttc agcttgttca taacctccat ccacactgta ttttatttca
     9481 tttgtagaat ttaatattgc tacagcattt ttcacttcat atggattaag aaactccgta
     9541 gacttaacat catagttttt tatacaacta ttagccttgt ctatcacttt aaacatttta
     9601 tttttcaagt ctatatcctt tatgtgattt gttagtttta atttatccat cctatcacct
     9661 tagaatataa ccaatactaa ttgtcttagg aacatcaata atactattgc aattaaagga
     9721 gaaaaatcta taggcccatt tgtatattta tacattatgg accttattgg cccttctatt
     9781 ggctctgtaa gattttctaa aatatcaaaa attttacttt gtcttccatt tggaaaccaa
     9841 gtcatcaagc tttttataac tatcatccat gctattatat ctaaaagata ataaagtgca
     9901 attcttattg ttcccataca ttaaccgcct ttttactatt tattttgcca agggaagaat
     9961 gctttacttt ctaattcttt tttcatattt gcatctatat ccacattatt aggagctagt
    10021 ataaatattg atttagaaac cttctgtata cttccatcta atacataaac tgccccattc
    10081 ataaagttaa atatagattt acgaacttca gaattagtca atccttccaa attcactata
    10141 actgcccttc tttgttttag atggtctgct atagttgcag cttcatcata aaccttaggt
    10201 tcaactatta caactttcat ttgactagtt gtatgtaaat ttacaatttt atttgctttt
    10261 gcagtactaa atccactgtt catttcttct tcttgaacta tatcgtccat accactttca
    10321 tattcatctt caatgtaatc ttcttcttca tcaactatcc aattcttaaa tttagatatt
    10381 attccatttg acattattaa cttcctcctt aaaatttatt caatttgagt aattattttt
    10441 tatcgtagtt tctttctcca aagattgatg ttccaactct aacaatagtg gccccttcct
    10501 ctatagcaat ttcataatcg tgactcattc ccattgataa aacatccatt cctacattag
    10561 ggatatttag ttcttttatt tgttttgata aatctttaag acctttaaat acacctctta
    10621 tctcatcttc atcttctata aaaggtgcca ttgtcattag accttttatt tttatatttt
    10681 tatatttttc tgacacttct ttgacaaagt ctacaacttc ttctctatca agtccatgct
    10741 tagattcttc tttagatata ttaacttgta ctaagcaatc tatttctctg tttatttgct
    10801 ctgcacgttt ttgaatttct tcgcataatg caattctatc taaagagtgt atcatacaaa
    10861 ctttatcgat tatgtactta actttattgg tttgcaaagt tcctatcaaa tgccagttta
    10921 atttgttacc tataatatca tactttctag ctaattcttg tggtttattt tcaccaacag
    10981 aagtaattcc ttccctcatt gcctcattaa ctaagtccac atcaacagtc tttgtaactg
    11041 ccaaaagggt aatctccttg ctatctctat ctactttttt tgcagcttta tcaattttgc
    11101 ttcttatctc agacaaattg tctttaatag aacccattat tatcacctac tttatcctta
    11161 tatttgtgtt tatactgtta ggtcttaaaa ttattttgtc atatagatta acacttgtaa
    11221 ctccatttag gtcattttta taataatcca caaatacaga agattcattc tcataagtta
    11281 ttccttctaa tatgacaaat tttacacttt gtgattgttc attaattaca tatacaccac
    11341 gtttattgtc ttttgttttt atagaagttt taggtatttt taaacattcc atctgattat
    11401 atattatatc aaattcttcg acacttgtat cctgatttgc aacaatttgg ttacttattt
    11461 ttaattttac cattatttta ttattatttt catatatttt gtaaactttt gcatctattt
    11521 tttgctcacg atattcaatt attacatttt gatttttttc aaagttatta gaatcttctt
    11581 tactgatgta tgtagataga taattgcttt ggtcattggc atctttttct atagctcctt
    11641 ttacatgaat ctttgcatcg actttttcat tttttaacac caatgtatct acatttttgc
    11701 taattatcat tactaatata ttaaatacta aatatataaa aataccaagt atcactaatc
    11761 tggtatattt aacctttttc aaagactctc cccctataaa atttctttca ttataagtac
    11821 ttcttctaaa aaatgtttat tcctttttta taacctaata ttttacattc taataattat
    11881 tttttccata ttaaatttat tttttatcaa tcttcctata caagactgca ttatttatat
    11941 ataattatat tataaagtat aagtttaatt tacattttat acgttaagct tactttatat
    12001 gttttatagt tatttttatt tttagatgca atataaaacc aattaagatt taaaataact
    12061 tttgttctgt tgacatttat ttaggtaatt atttatgcat taggataacg ttgtcacaac
    12121 aaaagtttat gtcctaaaaa aaatacaagg aggattttct tatgtcagaa attttattag
    12181 gaacaggttt acttttattg gttctatgtt gtttcacaat ttttagttac aaggctccat
    12241 atggtatgaa ggctatggga gctttagcaa acgctgcatg tgctactttc ttagtagagg
    12301 cattcaacct ttctttactt ggtgatgttc tgggtatgga attttttaga agtgtcggag
    12361 ctgctaatgg tagtcttggt ggagttgctg ctgctatact tgtgccttta gctttaggtg
    12421 tatctccagt ttatgcagtt ctaataggat tatcttgttt agatttttct atattatctg
    12481 gattcgttgc tggatacttt gtttctttct taattaaatt tatagagaaa aaagtaccac
    12541 ctggagtgga tttagtggtt gtaattcttc tatgtgcacc actatctcgt cttatagcat
    12601 caaatgtaga cccattagtt aatagtacac tactacaaat tggacaagtt ttgatagaag
    12661 ctacaaacat tagccctata ataatgggaa ttatactagg aggtctaata acagtggttg
    12721 gaacatctcc acttagttca atggctctta catctataat tggtcttact ggccttccta
    12781 tggcgatagg agcattaggt gcttttggtt cagcttttat gaactcaacg ctatttgcaa
    12841 aattgaaatt aggttctaaa aaagatatta tatctgttgc tattgaacca ttgactcaat
    12901 cagacataat ttcagctaat ccaataccta tatattctac taatttcttt ggaggagcct
    12961 tttctggtat cattgtagcc ttgatgggtc ttgtaaacat gactccaggt acagctacac
    13021 ctgtggctgg ttttgctata atgtttgctt ataatccagt tcaacaagtt cttataacag
    13081 ctggtttatg tgctttattc aatgtaattg caggattttt aggttcaaaa atattcagta
    13141 cctttaaagt tcttactgct ggtgaaatac gtggtactga tgtagaagaa gaaattgctt
    13201 aaaaaaacaa taagatttat aaatttatat ctcaagtagt agagttttat attgtaggca
    13261 attttatcaa ttgcaaacgt tttatttttt atttatgttt atgattatta tgtgtgttga
    13321 atatttagat aaatttttat ttattatttt tgtttagttt tttatttggt tgatatatta
    13381 ggaataagaa ttagtatact tcattactaa ttaaataaca taacttttta ttaaataaca
    13441 taacttttta gatatataaa aaactttata ttaattagat attattaaaa taaaagcgat
    13501 acatgacctt ttaaatgtcc atgtatcgct ttatttttgc cacaatctta acaactaatt
    13561 tttaaaattt attatcttaa ctataatatt taaatacata tacttattta atttaaccat
    13621 ataaatattt aattaaatat tatcatatgt aatatatcta atttttaaat gaatgtatag
    13681 gggctggaat ccttcctcct ctttgagtaa atagttcaga tgaatttgta tttataggca
    13741 ttactggtgc tcgtcctaaa agacctccaa attctaccat atcacctaca tcacatcctg
    13801 gggctggtat aattctaact gctgtagtct tattattaat catacctatt gctgcctcat
    13861 cagctatcat ggctccaagc gtacctgctg tagtatttcc tggcacagct atcatgtcaa
    13921 gacctacaga acaaatagca gtcattgctt caagcttatc tatacttaaa gcgcctttga
    13981 taacagcatc aatcatacct gcatcttcag atactggtat aaaagctcca ctaagtcctc
    14041 caacatgtga acatgccatt actccacctt ttttaacagc atcatttaaa agtgctaatg
    14101 ctgctgtagt cccatgagta ccaacaactt caagacccat ttcctctaat atgtttgcta
    14161 ctgaatcacc aatagcaggt gtaggagcta atgataagtc tattattcca aatggaacat
    14221 tcaatctact agaagcttcc tttgccacaa gttgtccaac tcttgtaatt ttaaatgctg
    14281 tctttttaac tgtttctgaa acaacatcaa atggctctcc ttttactttc tctagagctc
    14341 tcttgacaac accaggacca cttacaccaa cgtttataat tctatcagct tcaccaacgc
    14401 catggaaagc tcctgccata aatggattat cttctactgc attacaaaat actactagtt
    14461 ttgcacaacc aaaacctttt gcatcttttg ttaattctgc agtttctttt atgatttctc
    14521 ccatttctct cactgcatcc atatttatac cacatcttgt agagcctaca tttactgaag
    14581 cacatacttt attagtactt gctaaagctt ttggaattga cttaattagt atcttatcac
    14641 cttttgtata tcccttttga actaatgctg agaatccacc aataaaatct atacctaaat
    14701 cctctgcagc cttatccaat gtctgtgcaa actttacata gtcactttca tctgttgcac
    14761 ctgcaataat ggaaattgga gttactgata cccttttatt tacaattggg ataccaaatt
    14821 cacgctctat atcctttcca accttcacca aatctttagc agagctcata atcttattgt
    14881 atattttttc tctagcttta tctccatcag ggtctataca atctaataaa gaaatcccca
    14941 tagttatagt tcttatatcc aactgttctt catctatcat ctttattgtt tcaagtatat
    15001 ttcctacatt cactgttatc acctcccctt actgtctact acagattatg cattgaatta
    15061 aatatttctt ctcgctgaat ttttacatct actgataatt tcttacctct ttcaaccaag
    15121 tcctcaaccg ttttctcaaa agaatttaat gatttttcta agtcaactat cataatcata
    15181 gtaaaataat cctgtaatat cttttgtgat atatctacta tattgatatt ttgcttgtat
    15241 aattcatcac taattcctgc cactatacct ggtttatcct ttccaattac tgttaaaatt
    15301 gctttcataa taatatcctc ccttattttt ttatgaatct tatattttta caaattgaac
    15361 tatgtattaa catacatttc atttatttgt taataaatca ctttttatgt atatatttaa
    15421 tatattttaa tacctataca ttcatttgtc aatttttttt caatattcta ttatttttat
    15481 actatttaga aaattcacgt attatatatg ttttctcaac attaaataca gttttcataa
    15541 taatgaaagg tattacttag taatctcatg agtttataaa taataccttt ctaaaaatta
    15601 ttttttttct tttatgaact taattatact ttttctagta tcagaattta caattaatat
    15661 agaaccaatc ataattggtg ttagtatgca agctaaaaaa ataatgtctt tttttagatt
    15721 atattcttta gattctaatt tataattatt atttattatt ccattgtaat cacttatatt
    15781 tgacttattt ttatttgtat cttgattttt attagaaata ctttctctat aaggaaaaga
    15841 atgttcattg atgccaaata ttgattttaa atttaaatca taatcaccat cattttctat
    15901 aatagagctt ttattgaaaa ctcctttttc tttatcagaa ttattttctt tattaccatc
    15961 tttaggtata ttaccttctt tgggtatatc accttgagga tttttatttt cattgctacc
    16021 agtacttgat tctacatcat cttttggagc atttggttgt ttttcatcag aattatcatt
    16081 ttcattatta ttattttgat tgttattact atcattatta tcatttccat tatttccatt
    16141 ttgactgtta tcatccttat ctctatcagg gtcgtctcta cctcctcctc cacggtcacc
    16201 atcaatatca tcattttcct gttcatcatc tggcgtctct tggttgtcgc cacctcccat
    16261 tataaaacct ggtttaaaaa ctatatttga atatccttct tttaatcctc ctaccactct
    16321 tattctaaag caacgcaact taaaatcttc aaagaaaagt atagcttggt ctctaatatc
    16381 ctcctgttct tcagatatcc aattgattcc gtcgcttgaa tattcaacaa aaaccttact
    16441 tgcactatac ggcatgtcat aaaataaagc agctacatat ccttttttcg tattttgaaa
    16501 ttccaattct aaattgtcta ttggtttttt atccataaca tatatattca aaataggaac
    16561 tacatcatca tttattataa ttttttcttt atttaatgtt tctgttttga actttcctgt
    16621 tatgttaaat ttttctcctt tttctaattt ttcataataa tcagtaaaat cccattctac
    16681 atctatatca agttgattac cactagatgt ttctaatacc atatattgtg gaaattttat
    16741 attttctatt ttgtcatctt tacttacttt tatttcttca ctaaatacac caatccccct
    16801 ataacaacat ttcacaatat tgtagccaga gtcttcagct atagagggta taagttcatt
    16861 ataactatca attatataaa ctttcttgct ttctgatata attgattgta ccaacttatt
    16921 attatctctt aataactcat tttcattgtt gttactatat gcctttattg aagattcttc
    16981 tatctcaaca tcacctttag aataaacacc tatagcacgc tctccagtca cttcaatatc
    17041 cttatttatt attctaatat cattttcagt ataaattcct attgcatctt ttccatttgc
    17101 ctttattttt tcaacagatt cataggatga tttaatatat aagtctcctc cttcctcaac
    17161 gtataatgct gtcccgtcag tagcaattat gttatttata ccaatactta tacttccacc
    17221 attttctaca tgtattactc cttcttttcc tccttcacct attatattta gttcattatc
    17281 atcaataata aatctcccat gattttttat caatatttta tatttgttag tatctattgt
    17341 aaaattgctg tcataaggaa tataaaatct aaactcttcg tctattacca tatcgcaaga
    17401 aagagtataa actatttttt ctttattatt tttattttct tgaacccacc tttcaaaatc
    17461 ttcaagacaa ttttcctctt gtccaaaaac tttatatgga aaacttataa aacataaaac
    17521 tactatactt ataaaaataa atatctcata ttttttcatt ttacactcct agaaattttt
    17581 tagctttaaa caatcttgtc gaaacatata cttcacttac tataattttt ccataattat
    17641 caattattgt caatttatat aagtactttt attaattgct ataaataaaa agctacttac
    17701 taaagtaaac agacgtttaa ctttaataag tagctatatt tttataacaa aatagttata
    17761 atattagaac ttccttcatt tacaattttt tgtaaagtct tttgcatctt gactcttatt
    17821 tcttctggca tagtatataa tttactttgt aattgttctt ttactaagtc atgtaatgat
    17881 ttgccaaaca tatttgattc ccataagtct gctggttgct cttcaaatac ttccataaga
    17941 tattttatca tctcttcacc ttgattttga tttccaacta ttggagaaac ctctgtcgat
    18001 atatctgctt ttataatatg aagtgatggt gcattggctt ttaacttgat accatattgt
    18061 tttccttgtt tcattatttc tggctcttcc agactaagtt cttctaaaga aggagctact
    18121 actccatatc cttttatctt ggcatctatt aaagcacttt ctattttatc atactcattt
    18181 ttaactttag atagtctagt tatcagacta agaagttgat aatctccttc aattttaaat
    18241 ccactttttt cttcaaggac attatagaat aaatcttgct ttgtctgcaa atcaatattt
    18301 ataacacctt ctcctaactc tacattatca acacctgtat cttccaaaaa ctctaattca
    18361 gaaaatcctt gcataatacc ttctatatct cttattttac ctatatctat aatactttgt
    18421 tttaatgttg ttattatgct actttttatc caatgatttc tttcaagacc ttcaacccat
    18481 tttggtaggt tgattcttat ttctgtaagt ggaaaatcat ataatacagc ttccataacc
    18541 tcttctatat cttcttcttc catttcaacc acattcattg gaagaactgg aacttcatac
    18601 ttttcttcca attcacttct aagcatgctc gtttcctcac tttttggact taacgtattt
    18661 aaaaccactg caaatggttt tttaaggttt ttcaattcct gtataactct ctcttctggc
    18721 tctacatagc tctttctgtc aattccagta actgaaccat ctgtcaagac aactatccct
    18781 attgtggaat ggtcttttat aaccttttta gttcctattt ctgctgcctt ttcaaatgtc
    18841 atagcttctt gtgaccaagg agtagatact aatctttgtt ttccaccttc ctcatgccct
    18901 aaagctcctt caactatgta tccaacacaa tctaccattc ttacttttaa agatactgtg
    18961 tcttttattt ttatttctac tccatctgct ggtacaaatt ttggttctac tgtcattatt
    19021 gttttacctg aaccactttg aggtatctca tcccttgttc tatccttttt aaattcattg
    19081 tctatattag gtataaccaa cttttccata aattttctta taaaagttga ttttcctgtt
    19141 cttacaggtc caactactcc aatatatata tccccctgag tccttttgga tatatcttcg
    19201 tatatgttat tattcatatt attcctccta tacatctaat cttattaaat tatatttgga
    19261 tttcgaggtt aatattctta aaatggaaaa ataaagacca gcaatattaa tttcgtttac
    19321 agatagaaat tctttcattt tctgctctat agttttcata ccaaacctgt ctactatgta
    19381 ttactatatc tcctctttga agtattctag tattggagtc taaatgaagt tgtgctgttc
    19441 tatcaatccc tgaacaaata cagttaaaaa attttatata catataagga tacttttaag
    19501 aaacatattt tagtaaagca ttgtctccta catcttttac atatctcatt tcaaatattt
    19561 tacttccaac atctttgata acaaatgatt tatcagtcat atactctgaa aaacttgcag
    19621 atactatatg tttttctatt ccaacagttg ttcccttagg atttatataa caaaacaata
    19681 ttatgatatg tttccagaag atttaggtgt tcatgatagt gacatatctt taatgattac
    19741 aggagaaagt ataaaggaaa gaaataagat actattaaac aatcttgtag atactggata
    19801 tataccagct aaagatttag acataattaa tgatataatt atttcttttt atcaaaatct
    19861 attattctta aaaaagaaca caggaaaaaa ttctgatgat gatgaattaa ctatgaaaac
    19921 gatttcttct attgaataca taataaaaca tgctaaataa aattaaaata tggctgtctc
    19981 aaaatagaga taagcctttt ttattgttga aataataaaa atacatttaa tttcatacaa
    20041 aaagagtgtc tcataaacta aaaagttcat tttgagacac ccctaaaaca aatttattat
    20101 ttattataca atagtttata tatcatcacc taaaactact tcttccattt catgcttttt
    20161 acttctcatc attagttcta ttccaacttc tttaggattt gaacctttct ttattacaga
    20221 atatatagca ttagttatag gcatatctat atctaatttt tcagcgacat catgtgctac
    20281 ttcagtagca gttatacctt ctacaaccat ctttacttct tttaaggtat cttctaaact
    20341 cataccttta cctatgagta taccagctct tctatttcta ctatgcatac ttgtgcaagt
    20401 aactattaaa tctccaatac ctgaaagacc tgcaaaggta gacatattag ctcccatagc
    20461 aattccaagt ctgctcattt cactaatacc tcttgtcata agagctgctt ttgcattatc
    20521 accatatcct aatccatcac atatcccagc tccaaatgct ataatatttt ttaatgctcc
    20581 tccaagttct actccaacta tgtctggatt cgtataaact ctaagtttag ggctcataaa
    20641 taagtcttgt atcatctgtg ctatttttaa atctttagaa gcaactacta cggtagtagg
    20701 aatatccctt gctacttctt cagcatgaga cggcccagat agtattacat atggattttg
    20761 tggtaattct tcttcacaga cttgagataa cctaagccaa gtcccttttt caagaccttt
    20821 ggctacatta acaataactt gtccttcttt tataaatggc tttatttttt ggcaagtact
    20881 tcttacagcc tgtgatggaa ctgctaaaat tattacctta caatctttta tagttttttc
    20941 tatatcagta cttatagtta tattatttgg aaataatact cctggtaaat agtctgtatt
    21001 ttctttagtt ctgtttattt ttttagcttg ttcctctttt cgagtccaca tgctcacatc
    21061 attacctttt tttgcaagcc ctaaagctaa tgcacttccc cagcttccag tacctaatac
    21121 acatactttc tccatgttta acaccacctg agtataatat atttactatt ctttcttttg
    21181 accaattttt ctctctgtcc catttaataa tcgctttata tttgctctgt gattatatat
    21241 tactgatgca gttaagaaca aagctactat taaaccagct ttatttttta ccataatcat
    21301 aaatattggt gagcatccta tccctacaac agaacctaat gaaacatact ttgttataac
    21361 taccaccaat ataaatactg ctagacacat tagtgttatt actggattta cagctagcat
    21421 tgcccccagc gaagttgcaa cacctttacc tcctctaaat cctaaaactg ctggccaatt
    21481 atgacctgcc acaacacata taactgccag atatccagct aaaagagtat ctattccaac
    21541 caatcttgct gcaaactctg atattaaaac agccatcaca cctttaagaa catcacctaa
    21601 aaatgtcatt gctcctgctc tttttccaag tgtcctaagt acatttgttg aacctgcgtt
    21661 accagaacct tgagtcctta tatcaacccc agcaattcgc tttgcaacta tgtatgaggt
    21721 agatatattt cctaaaagat atgcaactac agcaataatt atataactaa atatctccac
    21781 tgaatttccc ccctttagtt atattttaga tatttatttt ttattttttt gtctatactc
    21841 aaactttatg gaagttcctt caaatccaaa attttctctt atcttattct caaggtatct
    21901 ttgatatgag aagtgagtta attccttatc atttataaac aatgtaattt taggaggtct
    21961 aatgtcagtt tgagttccat agtaaatttt taatcttcta cctttgtcag atggtggttg
    22021 atttaacatt acagcttctc caattacttc attcaatgct gaagttgata ttctcttaga
    22081 atgttcattt gacacatatt caactgtatc tagtatcttg ttcattcttt gattagtctt
    22141 tgcagaaaca aatacaattg gagcatacat cataaatgga aatttttctt ttatatcttt
    22201 tgtgtaattg ctcatagtct tattatcttt ttctattaaa tcccatttat tgattacaaa
    22261 tatgcatcct tttccttcat catgtgctat acctgcaacc tttgtatctt gttctgttac
    22321 accttctaag gcatctatta ctatcaatac tacatctgct ctatctacag cactcatagc
    22381 tcttattaca ctgtattttt ctattgtctc atatatttta ctttttcttc taagacctgc
    22441 tgtatctatt agaagaaatt tctgtccatt tttttcaaaa taagtatcaa ttgcgtctct
    22501 agtagttcct gcaattggac ttacaattac tctttcttct ccaagtatct tattaagtat
    22561 agaacttttt cctgcatttg gtttacctgt tatagctact cttattatat cttcttcata
    22621 ctctgtatct aatcctgctg gaaaattttc aactatctca tctaataaat ctccaaatcc
    22681 catactgttg gctcctgaaa ctgcaaaagg cgttccaaac cccaactcat aaaaatcgta
    22741 tatattatca aattgacttt gactatcaat cttattaact actaagatta ctggtttttt
    22801 tgtctttcta agcaattgtg caatttcttt atcagcagct gttattccag ccttaccatc
    22861 aactataaaa agtattacat gtgacatgtc cattgcaagc atggcttgat ttctcatttg
    22921 agataatatt atatcttcgc tatcaggttc aattcctcct gtatccacta atgtaaaata
    22981 tttatctaac cattccactt cagcaaaaat tctatctctt gtaactccag gtgtattttc
    23041 aactatcgat atcctttttc ctgcaaattt attaaatatt gtagacttac caacgtttgg
    23101 tctcccaact acagctacaa ctggcctact tatactcatt ttgtttctcc ttccatcttt
    23161 tgttttctat tttaaaattt tatccacaaa gtctttacct tcattcaagc aagggataat
    23221 ttttattttc ataagttctt ctaattgatt taattcaata ttatctaaga aaatttcttc
    23281 atctgctttt agcatacttc ttgttatata aagagcttct cctaattctt tattttcaag
    23341 ttgttctttt aaatctttag ctgttaaaag accagataca gttattgtct ctccaaaaaa
    23401 tttattttta atttcataga catttatttg aagattttta aacttgtcca tcatagcatt
    23461 tgccatactc tgtataaatt catatgcaga atgaccagta gctattgata ctttcttatc
    23521 tctttttaaa atatcctcag gcaatatatt tagatactct tcaatctctg tttttaactt
    23581 acgtatcata cctacaccat cttcaaactg taaaaaacct tcatattctt catatccagg
    23641 caattcacta ttagatagta tataaaattc atctgataaa aatgcaaatc gagtacctaa
    23701 ttgtttaaga tatttctgtt gcatttgatg tatttgctct atagttttac ttgcgctctt
    23761 accattaaat atatttaatt ctactagatt ttctctatgc tttgtaatcc caactggaac
    23821 tatagcaaca ctatttacat acggataaag ttgagctagt tcttttattg ttctatccaa
    23881 ttcctttcca tcatttatgc ctggacataa aacaatttga cagttcattt ctatatgagc
    23941 atctgccaat ctcttcatta taccatataa ttttcctgca aatttattac ttatcatttt
    24001 ttgtcttaac tctggattag ttgtatgcac agatatattt ataggactta ttctatattt
    24061 tataatatta tttatatctt cttcactcat atttgtaagt gtgacaaaat ttccttgtaa
    24121 aaaagacaat cttgaatcat catctttaaa ataaagagtt tctctcatac cttctggcaa
    24181 ttggtctata aaacaaaaca tacacttatt tctacagctt ttagcttggt caattattgg
    24241 atttgtaaat tcaacaccca aatcttcatc atagtctttt tctatctcgt atatgtagac
    24301 ttcaccatct tttttttgta tttctacctc taaatattca tcacttagta agaatctata
    24361 ctctattata tcatgtattg gttgttcatt cacagatata agtaaatctc ctacctctat
    24421 acctatttct tctgcaatac tatctttgta aaccttactt ataatattat ttactttttt
    24481 tacatttact tccaatattt tcaccactct tttgtattca tcaatgctta ttataatata
    24541 tttttatata tagtttactt atttattata ttttatggta gcatttttaa gcatttcatg
    24601 tcataataac acattttaat tctaatagtc aatataagta gatagctata aactagatta
    24661 aaacaaataa tattcaaatt taagtttttt aaaaatttga atattatttg ttcttaaaaa
    24721 atttataaat ttaatgtttt actatgatta gcgtcccatt cgtcatatca tgaaccattc
    24781 cacctacaca ctttgacatc aacaatgcct tattttgtaa gtctttctca tcgtttgcat
    24841 aaaatattgg acaacctcca ccatttttca tattcttatc aagtgtaact atagctaggg
    24901 tatattcatt taaacctata tccatcccca tcttatgcac ttcctttctt tcctatttta
    24961 taatttttta gtgataagtt ttttccttta gagcttgaaa gtattgggca tgactttaca
    25021 gcttccatta ctttttctac attcttatct actggtaaat aagcaatcat tatactttca
    25081 tcctctttat ttcttctagg taatggtaca aatgaaggtt ctccataatc tccatataaa
    25141 cctaacctcg aatatatatt gtatactatt gcttgtcttt gaccagaatc aaataatatt
    25201 cctgcattag cataatcttt attcttagga attatttgta ttcctacacc tctattaata
    25261 tatacttctc tatcactttt tagacctata tttgttatac cttttaaatc tccaaccttt
    25321 agtatagact cgtccacaaa actaatctca gcaggcatta catcagctat gtctccaata
    25381 ctttttctag taaggagttt ttttaatata aaagctagca ataatccaca aattgaactt
    25441 attaccaaac tcatcccttc acttattttc gtttctgcaa gtattacata gtacaaccct
    25501 attgttaaaa aagaggtaac tatgcacata taatttctca cttcataggt tctagctatc
    25561 tcttctatga atgcagcacc tctctttaca agctgaactt cttctaaatt ttgcaacgta
    25621 tttctcctat ttgctctcac ttgtctaaat tgttctgctg ctagagataa aaatgttata
    25681 gatgtataag aacgatttat aagagctgga accaataatg ctcctaatga agaagcgacg
    25741 aatgctaata taagttgaga tattaaaaca tttggttgcg ttggatactg tttttggtct
    25801 aaattcaaca ttataattct agatgttata ccaataataa cagcaacaaa aaatactcta
    25861 tccattaaat cactcctaaa atattttagt ttaaaatttt acatgtaaat ctacaaagtc
    25921 tttctagaaa aatcactctg ctttcctttt gatgtctcta tgataggtgt acttttcact
    25981 acatctatca tgacgtctat atctttgagt attggcatat acggtataac cacagtacgt
    26041 ttttccaaat tggtcttaga tatagcaaca atatcaacct catctacatc tctatctatc
    26101 cccatatgaa taaatagatt atgtattata gcttgtcttt gccctatatc gtttactatt
    26161 ccaaatgcac ctaaatctct tggtataact tctatcgcca gacattcatt tctatacttt
    26221 tctctcgtac tttctagacc tatattggtt attattacat catttaccat taaaatagga
    26281 ccttcaaagc ttatttttgc aggaactata tctgctatat ctgcaatact gtttcttctt
    26341 aaaaatcttc taaaaatcaa accaacaata gctcctgaca caatagctaa gattgtacaa
    26401 taaaaaaagc taaggtcgta ctttcttgca aaaacgatat aaactatcga agatactagt
    26461 gcagaaaaaa gacttatata acttctagat tcatacgtag atgctatttc ttcaacgtaa
    26521 gcatctcctt ttggtactaa ttcttcatta tcgatattct ttagtgttat tctttcttgt
    26581 tccgcaagac cttgaaactg ctgtattgct actgcaaaaa atgtcaaggc tgcaaactcc
    26641 ttatctataa gtgcaggcaa tgctatagca cctaatgaag ctgaaagccc agatataatt
    26701 atctgttcta aataatcttg tggtcttgat gggtattgtt tgtctgtaac tcttaaaact
    26761 agtcctctac ataatattcc tacgactaat gcaactataa aagagtgtct aaataaattt
    26821 gcatttaata aactttcttc cattttctca gctccttctc ttatatagtt tgtgcaaaaa
    26881 acaaaaaaaa tttccttcta tttaaggaaa tttttttgta atattgtaac tataaattcg
    26941 ctaccaatgc caagttcact ttttactttt atacatccat ttagtgattt aactatatgc
    27001 tttgttatag ccaatcctaa acccgttcct cctacatccc tacttcttgc tttatctacc
    27061 ctataaaatc gttcaaatat gcgttctaca tcttcttttg gtatacctac accattgtct
    27121 ataactttaa ttactatttt ttcttcatct tttaacacta caacttgtac aatcccatta
    27181 tcttgggtat actttatagc attatcaact agatttaaga acacttgctt tatatagtct
    27241 ttattagata gtatacttat tgatttatca tcacatttat ataaaacttc tatatttttt
    27301 tcactagctg aatgttgagt tatttcatat acttctttaa atacatcata cactacaaca
    27361 ttttccataa gaagagtatc tttattttct acaaacgata acagcaatat atcatcaatc
    27421 aatcttttta atctatctga ttcgctttct attatttcta agaatctatt tctagtattc
    27481 acatctatat tttcatttga ctttagtgtt tcgacaaatc cacttataga tgtaagtggt
    27541 gttttaagtt catgacttac atttgcaaca aaatcacttc tcatattttc aagtttaact
    27601 tttttagtaa tatcttctat atttactatc gaacctatta ttacgttgtt agtattttga
    27661 agataaactg ggtctacttt tattttatat actatatcat ctttagtagt aatattggca
    27721 gtttcattat ctttagagcc aataaatcga agtatttgtt ttaatatttc ttcttctttt
    27781 attacaacat taatattatg accttcaact aattgatttg gttcactctt tatcatttct
    27841 tttgcttcat catttatcag aagtatattg ccatttacat ctatagccaa aattccatga
    27901 gatatactct ttaatataga ctttaactgt aaatgcttat actgcacttc ttctaatgtc
    27961 ttatccatat tctttatcat atgattaaaa tttctagcta attcaccgag ttctccttta
    28021 gctgatatat taagcctagc atgatattca ttattactta ctttttttga gacgtatata
    28081 aattctttta aatatttcct taatgttatt gtgtatctta cagctaatat cacaatagct
    28141 atggacaaca taacaataaa aaaatataca ctatttaaat cttccacaag ataacactcc
    28201 taaaatataa cctttttaat ctattttgta tcctacacct cttatagtct ctatatattt
    28261 ttctgattta tcttcatctt ctattttttt tcttaaatat cttatatgaa catctactgt
    28321 tctagtttct ccatagtatt catatcccca tattttatcc aaaagataat ttcttgaaag
    28381 tacttttcct ttattttgaa tcaatagttt taataattca aattccttaa gagttaactc
    28441 tatcttttca gaacctttgg taacttcatg ttttgataaa tctagtttta aattacctgt
    28501 agtaagtata ttgttttctt cacctaagct agtcaaatta tatctcctta aaacagaact
    28561 aatcctagct aacaactctt ttatactaaa tggcttagtt atatagtcgt cagcacctat
    28621 ttcaagccct tcaaccttgt cattttccat atttttagca gtaagcatta taacaggaat
    28681 attttttaag tccttatcac ttcttatttt tctcaaaact tctattccac ttatatttgg
    28741 taacatccaa tctaaaagta ttaaatctgg tttaatttcc ttggccttta taaatccatc
    28801 aaatccatca tatgaataac taacttcgta atttgacacc tccaaattga attttaatag
    28861 ctcaactata tgcatttcat catctataac aagcacttta gtattcatta aaaagctcct
    28921 ctctatttta tctgtagtac cgttcctatt cgttctgatg ccttattatg ttttctataa
    28981 gagtggaatt tatctgctct acaactagtg cataaattta aatttattat attttctttt
    29041 ttaactccac tacatataag catatactca ttaattttcc ataaatctaa atagtaactc
    29101 ccctctttta ttatatagaa cttttcatca ttatttgtaa gaattgtgtt aaatttttct
    29161 actaaatctt cagacacttc ataacaacaa ggtccaattg atggcccaat tatacatact
    29221 aaatcttcgg gaactgtttt atagcattca gacattaatt ttattgtttt atgacctata
    29281 ttactaaaag tacctctcca acctgcatga gccagtccta tggctttatt tttagcatct
    29341 ataattgata taggtacaca gtctgctgta aacagtaaaa gtggtacttt ttccaagttt
    29401 gttataagtg catccccatc tcttctttta cctatggtgt ctttattaac tatgttaact
    29461 atatctgaat gtatttgaga attactagtt aaattttcaa atgtcaagtc acattcttta
    29521 catactttta acatatcttc tctatttttt gcatctatat tcttacatgt tataactaga
    29581 tttacagatt ttaacttttc atcaatttct ttacaattac cacttaaatt aacatactct
    29641 ttaatatctt gtacattttt tatatttata taatctttca tcatttgtct cctttttcta
    29701 tcaatatact tttaagttca tttacaaaag tatttatatc tttaaattgt ctatacacag
    29761 aagcaaatct tacataggca acttcatcta aatctttcaa tttatccatt accatctcac
    29821 cgattttttt ggtttcaatt tcttctataa aacatttatt tatttcattt tcaatatgta
    29881 caacaatgct ttcaatctct tcaatagaaa caggtctttt ttcacatgcc tttaacaatc
    29941 catattttat cttttctcta tcaaaatatt ctctactatt atcctttttg attaccatta
    30001 aaggagttgt ttctattttc tcatacgtag taaacctctt tttacatgat tcacactcac
    30061 gtcttcttct gatagatttt aaatctgtat gtctagaatc tattaccttt gattctttat
    30121 aattacaata aggacattgc atctatattc ctcctttgtt taactatatc tcaaactcat
    30181 ctaagcttaa ttctgaacct atatttacta ttattgtatc acaacctatt ttaagtatat
    30241 cattccaaaa tataacttct tcatcccctc ctcttgaaaa aaaacttcta cttccatctc
    30301 caaaaatggt aaatgagact actttacctt cgtgaatatc catgtctatg tctattataa
    30361 accccatcct ttttccattt tttacattta taatttcttt ttccattata tcagaaactc
    30421 taatcatatt gtactcaccc tttctttaaa aataaatatg tatcgaagta aaaaaaaatg
    30481 acctatatag gtcatttaaa ttaaaataat gtttacagtc catggattac ttatacatat
    30541 tttctcatat tttttaaagc attcttttca attcttgata cttgtgcttg agatataccg
    30601 atttcatcag caacttctat ctgagttctt cctttgtaaa accttaaatc taataccaac
    30661 ttttctctac tatttaattt cttaatagct tctttaagtg atatttcttg caaccaattt
    30721 tcatcagtat cttttttatc ttgaacctga tccataacga atattgcatc tccattgtct
    30781 tgatacactg ggtcaaacag agatatcggg tcttgtatgg catcaagtgc cattacaacc
    30841 gactctactt ctaactctaa ttcctttgct atttctgata ctgtaggttc tttagaattt
    30901 gttctaatta atctttctct aacttgtagt gccttatatg ctatatcttt taatgaccta
    30961 cttactctaa ttgggttatt gtctcttaga tatcttctaa tttctcctat aatcatagga
    31021 acagcataag ttgaaaatct tacgttttga cttaaatcaa agttatctat agcttttata
    31081 agaccaatac aacctatttg aaataaatcg tctatatttt ctcctctgtt gttaaacttt
    31141 tttattacac tcaagactaa tcttaaattc cctcttacaa actgttgtct ggcttcttca
    31201 tcaccatttt ttatttgtaa taaaagctcc ttcatttgct tatttttaag aactggaagt
    31261 tctgatgtgt taacgccaca tatttcaacc ttattaactt gcatatattt tcagtcctct
    31321 ctcaaaagta ttcatctatt gaaattattt acatttccaa tttttttata ctttttaaga
    31381 agaattaatt taacattata caaatttttt catttctttt tgcaaccttg aaattatttt
    31441 cttttcaagt ctagatatgt aggactgtga tattccaagc attcctgcaa cttctttttg
    31501 tgttttttcg atacctttat caataagacc aaatcttaat tccataattt gcttttctct
    31561 gtcacttaat ctgtcaagtg ccataaccaa caaatctcta tctatttctt cttcaattat
    31621 tttgtatatt tcatcatttt ctgtacccaa tacatcagat aataaaagtt catttccgtc
    31681 taaatctata tttaaaggtt catcaaatga tacttctgtt ttctttttat tattttttct
    31741 taagtacatt aatatttcat tttctataca tctcgaagca taagttgcca attttatatt
    31801 tttattcagt ttaaaagtat taactgcttt tatcaaacct atagttccta ttgaaatcaa
    31861 atcttctaca tctattcctg tattttcaaa ttttctcgat atgtagacta ctaatctaag
    31921 atttctttct attaaaattg actttacact ttcatctgtt tctagctttt gtaaaagttc
    31981 catttcttct tctggtttca atggaggagg aagtatattt gcccctccca tatagtatat
    32041 tccctttggc tttattattt ttaatttaat acctaacata gtaataaagc ttataattct
    32101 ttctttcaat cgtaacattc cttgtccccc ttaaattttc acctaaaatc caggtaatat
    32161 atttggattc attattgctc catattctct atcattaaaa tttgaaatac caagtattat
    32221 atttcctatc ttttgttcat ctacttctat ataatcagct tttaaaccta ttattatgct
    32281 tgtcttattg cttccagcat gtttataagg tattattcta actctacctg aagttttatc
    32341 atctaaactt cctataattt cttgtgcttt tttcatatct atatcttcat aattaatatt
    32401 taatagtttt tctggaataa atccttctag cacacttgac ttaactatta ttacatcact
    32461 ttgacttatt gggtctttta acaaattacc actatctact aaagccttac agcaaaaact
    32521 tttttctagt aattttatat ttatagtctt tgtaagctcc ttaatgtact taagcatttt
    32581 caaatcttta taaatgtatt ttaataattc acaactcaca taagtacatg caattaaaaa
    32641 agatattttt aagtgactta ttcctgtaaa ataaattata aaataagtgc ttccagaaat
    32701 aaaaatgttt actagataaa aaactaaagc tacatgaaca taatcttttt tgctcttgct
    32761 tctaaatgaa attaaagtta ttatactcat gattattatt ttaaatggta tagtaaatag
    32821 tatattcatt gatggataca aataagcaac agaataggca cctcctaaac tagcccccaa
    32881 caacttattt tttttaggat tatatctttt agtaagaata gaagtacaac ttataataat
    32941 ataatttatt actaggtttt ctataacata gtactcaata tacaccatgt atcccccctt
    33001 aaaaccttta aacatattat aagatagtat gtacaaaatt ttatgtcact tttgatggtc
    33061 gaatccaaaa caaattctat ttaaaaagaa caatgatata tgtcttatac tttatgtcgc
    33121 caaaagatat ttttttaatg ccaaacaaat aggctttttt gtagaatcca atatatctag
    33181 gtagaagtta ttcgttctac ttttggtata tttccataaa aaaaagacta cataatttaa
    33241 taatatatca agtaaatctt ttacttatct aaaattaaat tatgtagtct gtaaattcaa
    33301 atataaattt aaattattgt gctaataatc catttgcata ttttgcagat tcatttagtg
    33361 cttgttctgg agttatgtct ccagctatca tcatttgaag ttgtttccat aagtattcat
    33421 atatctctac tccatgaggt ccaactgtta atggtctata catatgttta tctcttgtaa
    33481 ccatttcttc aaaccttggg tctccttggt atttttcacc tttagcaact ggagctctag
    33541 gtacttcttt gtggaaagct tccattgatt ctttgctcaa catgtattca agaagtttaa
    33601 atccaagttc tttattttta catgctgaca ttaatgttaa atcatctact gaagcaaaac
    33661 ttccaactgt cttatcttct aatgatgtta catatcccca gtttaaatct gggaatgatt
    33721 tatcaaatgt acttgtagca gcagaagaca acattatagt aaatgcagct tttcctggtc
    33781 caaatacact ttcaatcatt tcattactat cttttgacaa agcatcttct ggaatatact
    33841 ttttcatatc atttataaag tttgcagctt tcaaaccttc tgcattatta aatttaactg
    33901 attttaaatc atcattatat atacctccac cagcttgcca taaatacgga taccagttcc
    33961 agtttaaact cccaaatact ttagaacccc aaccttgtgc aagaccccac tggtctattt
    34021 ttccatctcc atcagtatct tttgttgctt tttcacatat tcttttaaaa tcatcccatg
    34081 tttttggagg tttctctcct aatttttcta gtatatcttt attgtaatac aatacacctg
    34141 gattagcagc ttctataggt aaaccataaa taccacccat catttttgca tcatctaagt
    34201 atagataatt atctgaagtt cctgattttt ctagataagg tgtcaaatct tctaccgcac
    34261 ccatttctat aaattgaggg aacatctctg catacatgta tcctatgtct ggaccttcac
    34321 ctgcacttat tgctgttgca tatttttctg cgtagttatc ccatggtact atctgaaatt
    34381 caatttcaca gttattttct ttttcaaatt tttcaaatat cggcttccat gcatctgcat
    34441 catggtctgt taatggtgca gaccacacaa ctaatttttc cttaccctct ttgcctttag
    34501 aatcttcttt ttttgaacac cctgcaagaa ttgatactga cagaatccct accataacta
    34561 aagaaagaac cttttttagt ttaatcatgc ttaatcccct ttcagacttt aatttgtctt
    34621 tttcctcaaa tgtttacatt taattcagat ttaatattaa caaataagac tactcttgtc
    34681 taatcacaaa aaactatact aactaccata actatatttt ttttctatac atattagatt
    34741 taatttacac taaaaaactt actttttaaa ttttgtcaat atttaaaagt gtttttaatc
    34801 ctagccacaa actaactatt taaattgagc aaaataaaaa gaagtctatt gacttcttta
    34861 taagcttaca tattatcttc ttcttcttaa gaatgtaggt atctccatac tctcatcatc
    34921 atcttcttca attatacttg cctttttagg aggctctatt ttttcctcag caattacttc
    34981 ttcttcaatt tcttttacag cttgttttac tgttgtattt aatgaggaac gtatgcttga
    35041 tttaggctta gtttctaaat ccaaggcacc attttgtaat ccttcaaatc ctgttgcgat
    35101 tactgtaatc attatttcat cacccaaatc ttcttttata gaagctccaa atataacatt
    35161 tgcttctggg tcacaggatt ccataactaa agttgatgcc tcattaactt caaataatcc
    35221 taggttagga ccacccgtaa cattaagaag aacaccttta gctccttgta ttgatgtttc
    35281 tagaagtgga gattgaatag cttgtctagc agcatcaatt gctctagttt caccactagc
    35341 actacctata cccatatgag caagtccctt gtctttcatt atagtagtaa cgtctgcgaa
    35401 gtccaagttt attaaccctt caactgctat aaggtctgaa attgattgta taccttgttt
    35461 taatacatca tctgcaactg caaaagcatc taacattgat gtattttttt gtactatctg
    35521 taaaagccta tcatttggta ttgttataag agtatctact tttgatttaa gctctgctat
    35581 tccaccttca gcattcttca tccttatctt accttcaaat gcaaaaggtt tagtaactac
    35641 acctactgta agtatcccca tttcttttgc caagcctgca actactggag cagctcctgt
    35701 accagtacca ccgcccattc cagctgttac aaaaaccata tcagctcctt gaagcaactt
    35761 tactatttca tctttactct cctcagcagc tctttttcct acttcaggat ttgctcctgc
    35821 tccaagtcct ctagttaatt tttctcctat ttgaacttta tattcagctt ttgatgtata
    35881 taaagcttgt ttatctgtat ttactgatat aaattcaacg ccttttagtt gagcttctac
    35941 cattctattg acagcattgt ttccaccgcc acctacacct attactttaa tttgtgcaca
    36001 ttcttctaat tctacgtcaa agtttagcat cataaacccc cttctctcat gattcaaagt
    36061 tatcgtatgt attaattata tcattttctt cttttatttt gttaaccttt aagtaacata
    36121 ttccacaaaa acgtaaattt tcctttttaa atttcttact tatattgtca aatattactc
    36181 tttaagtata aaataattta cgtatatatt aaatgctctt taatttttac gttttttatt
    36241 cataatatta ctaataatat atcgtctaat tatagataag ttattaaaca atctcatacc
    36301 aaaaactaat acagcaacat aataaagaga aattcctaac ttttctccta tataagtcaa
    36361 taatatagcc aatatagcat tacctatgaa acctgtaata aaaattacat tatcatagtt
    36421 atcttcaaaa ttggatttta tcgctccaaa aatagaatcc attattgcaa gaatagctac
    36481 tgacatatat atggaataat ccatagaata tgtaaatgga atatagtaac ctattactac
    36541 gccaaatgct aatcctccta aaacccataa cataaatctt cacctcttta ttttactttg
    36601 aaacacaact acattacaat cctttttgtt aatttttttt actttttctt tatttttttg
    36661 tatttttcgt tttattttgt aaataaattc actttatttc cattattttc ctgcactttt
    36721 atattaattc catatatatc cttaagagat ttagcgtatg attctggaga gtttatagca
    36781 gcactcaata aatctatatc tcctatagct tttattatga atggttgtcc atatgtagta
    36841 tcatttactg taatagtagc tcctgaacat tttatcttac tcgttgctag tactctttcc
    36901 ccatttatag aaattgctct tgctccagcc ttttttaaat catttaaaac tctcaaaata
    36961 tctatatcat gtataatcaa atcattcgga ttctgtccgt cttttaactc tctctcacta
    37021 tccttcatag taatagttat gcctggtcct gtaacacttg aataaccact taattcttta
    37081 acttcttcaa gttctttttg cataagtgtt tggatagatt cattaccatt cttttttgct
    37141 tctttatatt cattcaaagt ttttttgttg tttttaagcg tttcttttaa attttttatt
    37201 tctttttttg tattttctac ctcactttca atattttcag tttgacctaa tgttatgtat
    37261 actctatttg ggtctagtga ttttatataa gttgatatga aaatgcctaa tatgaatgca
    37321 cctaatataa ctattttctt tttcatactg ttatttcccc tctgctttgt ttatatcact
    37381 atgaccattt atttctatat tgtcttcctt ggtcactttt actttggcat tataatatgt
    37441 ttctatttcc cagacaatac catactttat attaagtgca gaagccaatg tatcagaatc
    37501 accaattgct tttattataa ttggttcttt tataacagtg tcattcatat aaagcttgtc
    37561 ttcttttaaa tacatatatg tattagaaac tattctctgg tcgtttatag atatggcact
    37621 tgcttgtgct gaatttaatt tatttatcat tgacaataat aaatcataat tatatagtat
    37681 actatcattt ttatcagagt ttcctaagtc ttttgtagaa cttatctcaa tttttatacc
    37741 tgttccttct acatctgtat atccagctaa tgtttcatat ttttctattt ctgacttaag
    37801 tatgtcttgt tcaccttcat tatttttgcc tctataagtc tctatatctt tcttcacact
    37861 attaacttct gattgtagat tctctttttc tttttttaaa gatttaagtt cttctgtgag
    37921 ttgctctcct cttttaaaag ttgtcatccc tctattttct atattaataa ttttaagttg
    37981 taaactaaca agaacaccta atacgatact tcctatgatt atacttttat ttataaatct
    38041 ttttttcaat atatcacttc cttacaattg tctatccttc tggactatac actgccaact
    38101 tcccataatt aagatttata gtacctccat tagtattttt attttgcagg tcaatcaaaa
    38161 ttttacttac cctagatata ttataatcta agttatcatc attagaaagt aagattttta
    38221 tattacttct tgtaagcatt tctatattgc tttctttttt taagtttaca taatttattt
    38281 ttctataaat cccttcttct tttaaataat ttaaagtttt aaatacattc tccttagttt
    38341 tataattttt aaattttata gatttattat catcaacact ataatctaca tctactatca
    38401 agtctttttt actttcatta gaacctctta gttcttctaa caaattgcct tttttatcta
    38461 tataacaata attatcttca tcttttaata ctgcaaatat ttctttttct tttaaactta
    38521 taattatctt attgggaagt tttcttttta tttccacatt ttctatatat ggatttttta
    38581 taagtttatt tttcatatct ttaaaattgt atgcaaaaat attttcattt agatttatat
    38641 ttagttcttt cattatattt gatttagtta ctctcttatt tccaattaca tctattttct
    38701 ttacatcaaa taaatcactt tttacaatta tacatataca aaaagataac ataagtataa
    38761 aaactaagac tatcatgaca ttattcgtat ttaattttct tctttttttc aaatataatc
    38821 aacccctttg gttaataaat acacctttag agcttatttt tcctacaaaa aaattataat
    38881 atttaaagtc aaatttttgc attttattac ataacatcca attaaagtat taaatcttat
    38941 aagtaaatca atatttcatc aaaataaata tagtatgcta tatatagtta aatccgtata
    39001 tatacaaata aacccctaat ttagaataat ttagaaaatc taatatatta taaattaggg
    39061 gtaaatattt acttatcttt tctttattcc tattacttta gcttgacctt ctatactcgg
    39121 agtcgtttct ttttttattt cttttacttc cttaataact ttttcttttt ttgttttttt
    39181 agaagttgac ttttgtgttg aattgtatac tttcattatc tcatcatata taaggtctat
    39241 ggcttcaggc ttacctatag ttttacttgc atttgccatg tcaaccaaaa gttctctatc
    39301 ccctaaaagt ttaaatactg ctgtatttag gctctctgga gttagatttt tttctaaaat
    39361 agcaattccc gcgccttgtt tttctatact cttggcatta tactcttgat gattttcagc
    39421 agtataagct ttaggtatta ttatagatgg ctttccaaga gctgttatct cagctaatga
    39481 aattgctcct gcactaccta taactaaatc acttgctgca agtgcatttg ccatatcttc
    39541 taagtaaggt acaacctttt gatatggttt aagatttata tcgctaatac tttccataaa
    39601 ttcatcataa tagcttttgc ctgtagcaaa tataaaagct atatcttcat ttaccatatt
    39661 ctttattaca agtctcattg catcatttat ttttcttgaa cctccactac caccatagca
    39721 aagtaccatt cttttttctt cacttattga tagatttttt cttgcaatat tttttcttga
    39781 taataaaatt tcttttctaa ctgggtttcc tgtaaaaact aatttttctt ctgctgcctc
    39841 aggaaatctt ttatgtgaat cttcaaaact tgtaagtacc tttgtaactg ttttagataa
    39901 aatcttatta gttacaccag gaaaagaatt ttgctcatgt attatggctg gtattttccc
    39961 catagatgca ttaaataaaa caggtccact aacataacca ccagttccta taactacatc
    40021 tggcttaaat ttcttaacaa tctttcttga ttgctccaaa cctttaaaaa gcttaaaaac
    40081 tctttttaca ttatcgaaat ctatttttcg cttaaagcct tgaactgtta cagtctttaa
    40141 ttcaaatcca tacttaggaa ctatttctga ctctattcct ttttccgtcc caacaaaaat
    40201 tatctcggcg tctggatgct catctcttat tttgttcgca atagctatag ctggatacac
    40261 gtgccctcca gttccaccgc ctgataataa aactttcatc aaatcatcat ctcctgttaa
    40321 ttaattttga catgctttga gatgtttaac actattccta cagctcccat aaagatggtg
    40381 agtgaagttc ctccataact tataaatggt agtgctacac ctgtagctgg cattgatgat
    40441 gttgcaactg ctatatttaa agctgcttgt attccaattt gtgcacctat acctataaca
    40501 accatacaag caaatacatt agaagttttc aatgctattc ttacacatct gtagactaaa
    40561 actacaaaca gcataataac tattatacaa ccaatcaatc ctaactcttc tcctattata
    40621 gcaaatataa agtcattttg cggctctggt atataaaaat acttttgttt actctttcct
    40681 aagcctagac caaacaatcc acctgaacct agtgcatata gaccttgtat tacctgatac
    40741 cccttaccaa gagggtcttg aaaagggtct aaaaatgatg taacacgact aagtctatat
    40801 ggttcagcaa ttactaatgc agcaaataaa gcaaccccac tccctatcat agcaaataca
    40861 attttcatat ccattccagc aacaaatatc atcacaaaag taactagaat tacagtacct
    40921 gctgttgaca aatttggctg aagtattatc aacgcaaaaa atatacctgg aactactaga
    40981 agtggtacaa caccttttgt caaagatttt attttatcat aatttctttc aattaatttt
    41041 gcagttaata ttattgtagc aaactttgcg atttctgcag gttgaaatgt taaagcccct
    41101 attcccaacc atctttttgc tccatttgct tctatcccta aaggggtcaa aactaacaat
    41161 aataatacta ctgctatagc tccaattgct gtagcatttt tcttccaaaa actataatct
    41221 attctcgatg taataatcat aactataaat ccaagcacag catatattac attctttttt
    41281 agaaaatagt acgcatcatt atgtttaaat gaagattgta taaaacttgc actaaacacc
    41341 ataactattc ctacaaatac taaaagcata gtagtataaa atactactcc atcaaattca
    41401 gtcttcatcc ttatgtcaat ttgttttttc aaattttctt taggcatcca actaatctac
    41461 ctccattctt ccatttaagt aagtttagag gtaagagatt attttaaatt gtttacatta
    41521 tctttgaagt cttttcctct tacttcaaaa ctttcataca tatcccaact tgcacaagct
    41581 ggtgaaagaa gcactatatc tccgcttttt gaaatttcat aagaagtctt aactgcttct
    41641 tccatatctt ttactatatg tatgtcatta aatcctttat ttttagcaca attttctata
    41701 tttgatgcag tttctcctaa tagaaccaat gatttaacat atgactttgc agtttcaaga
    41761 agttcatcaa aattacttcc cttatccatc cctcctgcta taagtattat aggtctatcg
    41821 taagactgta tagcttttat agtagaatct ggattagttc cttttgaatc attaacatat
    41881 attacattat ctaaatttct tacaaactct tgtctgtgtt ccactccttt aaatgtcata
    41941 agtacatcct ttataacctc taagtcaatt ttgcatacat atgctattgc tatagctgcc
    42001 atacagtttt ctaagttatg acctccaggt aaacttacat catctttatt tagaaatttg
    42061 attttatcat ctatatctat tattatgtca ttattttcta aatatactcc tccatttact
    42121 tttttagttc ttgaaaagta aattacttta gcattgcatt tatcagctag accttttact
    42181 atctcatcat cataatttaa tacacagaaa tcctcagaag tttgattcat aaatatattt
    42241 gtctttgctt ctatatactt ttccatagta tgatgtctat ttaagtggtc ttctgtaata
    42301 tttaatatgg cacttacttt aggtctaaat tcatctatac tttcaagctg aaaactactt
    42361 aattcagtta ctagcacaga ttcttcattt gaagtttcta tagtatctat cacaggattt
    42421 cctatattac caactacata tgtatctcgt tttgctcttg aaaaaatttc tcctaccaaa
    42481 ctagttgtag ttgtttttcc atttgtacct gtaattccta taaaaattgg attatttgat
    42541 agtttaaaag ctaattctac ctcaccaatt atatacttgc ctgaattttt taatttcaat
    42601 atgaatggta ggtctagtgg tacacctgga gacactacaa ccatatctat atcatctata
    42661 tcttctggat gatgtcctaa tatgtatttt atatcattta tagattttaa ttcatcaagt
    42721 atatttctca atttattttc atctttgata tcatttacta ttatacttgc acccaattta
    42781 tctaaatgtt taattgtaga tataccagtt tttgcaagtc ctactaataa aacttttttt
    42841 ccttttaaat ccatttttta ttccccccag ccctagaata ctgctattat acttatccaa
    42901 gccaaaacaa ctgtaacaat ccaaaaaata aatacaactc ttgtttctgg ccaaccacac
    42961 tgttcaaaat ggtggtgtat tggagccatc ttaaagaatc tctttcttgt tgctttaaaa
    43021 tatccaactt gaatcaaaac tgatagagcc tctgcaaaat aaattcctcc aattataggt
    43081 attataagca ctgagttagt tagaactgaa aatgctacaa ctgcacctcc taatgccatt
    43141 gaacctgtat cccccataaa cactctagct ggatatgaat taaatcctaa aaaacctaaa
    43201 catgctccaa cagttgctgc tgctaaaact gcgacttctg tatttccagc aatagaactt
    43261 gcaaatagca taaagaatac agaaactatt aatgttactc ctgatgctaa tccatctaat
    43321 ccatcagtca aatttacagc atttactatt gctacaatta taaacatcat tattggtata
    43381 tataatattc caacatttat tacaaaatct gtaaatggta tcataagttg tgaagcactt
    43441 gatgatgatg tatattgata aaaagcaaca taaaaagata atgcaacttg aaggattatt
    43501 ttttgatatg cttttagtcc aagtgatctt tttagcttta tttttataaa gtcatctaaa
    43561 aaaccaataa aaccaaaacc tgcaatacat ataagaccta ctgccatatc atgactaact
    43621 tttactcttg taagtccagt tattaaaatt gcaacaatca ttataattcc acccatagta
    43681 ggtgttccgt ttttagctag atgtgtttga ggtccatcat ctctaactgt ctgaccaaat
    43741 ttaaattttc taagcattgg tataaatatt ggtcctatta taattactat taaaaacgca
    43801 atcaatgcgg tgtacgtaag ctctgttatt cctaacatca taaaactcct ctcccttgtc
    43861 aattaactct cattagttta agcttattta tttagatatt cgactatttt ttctaatctc
    43921 atgcctcttg agccttttac taaaatagtg tctcctgttt ttactaattc atttaacttg
    43981 ttaaatacat cttctctatt ctcaaagtga tatatattgg ctgaattgaa tcctaattgt
    44041 tttgcttctt ctccaataaa cactgaattt tcacctatag ttattataat atcagtatta
    44101 ttcatagatg attttccaac taatctatga ccatactctg aaatttcacc catttctagt
    44161 atatctccaa gtattgctac tcttctacct ttatatcttc caagtatctt taaagcagca
    44221 tccatagaat ctggactagc attatatgaa tcattaatta ttgttaattt ttcatttttt
    44281 attatgtcta gtctcatttt tgtcccttta aaatttttca aacctttttt tatataatct
    44341 aaagaaatat ttagacataa accaactaat atagcagaca ttgcattata tatattatgt
    44401 tctcctattg ttggtataaa tatttcctct tttttcccat ttattacaca tataaatgtt
    44461 aaactatcct cttccatagt ataactttca caataaatat cattattttt attaaagcca
    44521 aatgttttta acttatatac atgttctttt tcctttaatg tagataaaaa cttatcatct
    44581 ccatttacaa ttaaagtatt tgcttcatca aagtttgaag taatctccat ctttgctttc
    44641 aaaatcccct cttgtgaacc taatttttct acatgtgata atcctatatt cgatatgact
    44701 gcgattttag gatttactat atccactaaa tattttattt cattgaatcc agacataccc
    44761 atttctatta cagcacactc atgttcttta cttagattaa ataaagtcaa tggaactcca
    44821 aaatgattat ttaagttttt ttcatttttt agtatattta gctttgcaga tattgcagaa
    44881 taaatcatat ccctagtagt agtttttccc acactacctg taacacctat aaacggaata
    44941 tcaaattttt ctttatagta ttttgaaata tttcctagag ccaaagatgt atcttttacc
    45001 tctattaaat ttatatccga actttctaat tttattccat tactttcatt ttttataaaa
    45061 gttttacatc cactatcata tgcagacttc ataaatgtat gcccatctaa attttctcca
    45121 actatggcta caaatgcatt ttgggcattt gcctccctgc tatctataac tatatcactt
    45181 acacagtcat tataatctcc atatattaac ttcccattag ttgcaagtac taactctttt
    45241 attgttaagc actccattat caaactcctc ctttaaaacc ttagctatat tctcttagca
    45301 acaaaaggca atgtataccg ttatatatac attgcctacg ataactctta actttataat
    45361 tatatactat atttctgttt ttttgaagat gtttatgggt atatgttaat tatctgttac
    45421 tttttagttt tcaaaatata gggttatact tgagtcttca ttaactttta ctccaggttt
    45481 tgggaatata tcctttacct ttgtatcttc tggaagttct atatctgcat ctaagtctgg
    45541 ttttaacttc acatcctcca atgcctttac agcatctcct atttttagat ttcttacatc
    45601 tggcacttta acttgcttct tctcatactc agctttttct tcttctttgt atactggttt
    45661 aactcctaaa tattttaaag aatcattcat tatttctttc actattggtc ctgctgtagt
    45721 actaccaaat gcgcttactc ctgttggttc gtcaacaata gcaagaacta ctatttgtgg
    45781 gtcatcacaa ggtgctattc caacaaatga acatatatat tttcctggag catacttacc
    45841 atctataact ttttgagctg tacctgtttt accaccaagt ctataccctg gtatatatgc
    45901 tatctttcct ccaccttcag ttacaactga ttctgcaatt tctaacattt ttttagatgt
    45961 ttctttagat ataacacttc ttactttttt tggttttact gtttcagtta tatttccttt
    46021 attgtcagta taagatttta ccactcttgg ttgcattaaa tctccaccat tagctattga
    46081 tgatatagct gttataagtt gtattggagt tactgatata gattgaccaa atgatattgt
    46141 agccaattca actggtccta catttttttc gttatacaat attcccttag cttctcctgg
    46201 taaatctata cctgtcttat ccataagacc aaatgattct atataatcat acattttccc
    46261 aacacctaat ctgcttccta actcaacaaa tactgggtta caagaatttt gtactgcttg
    46321 tttaaactct tgtgttccat gaggtctgta atgtctccaa catttaatct ttcttcctcc
    46381 aacagttaca ctacctgtac atgtgaattt ttctccatct ttaattactc cttcttcaag
    46441 agcactggaa gatgtaataa gcttaaatgt agaacctggt tcatatgtat cacttactgc
    46501 cggatttctc cacatttgat aatatccttt tattttatct ttatcattat atttttcaag
    46561 ttcttcttga taatatggat atattggtgt tcttgaatca ttagggtcat aatctggttt
    46621 tgatgctaaa gcaagtatat caccagtttt agggttcata gctattgcag taaccttttt
    46681 tgcattattt aactcatacg ctttctgtac tgctttttca gtatagtgtt gaattacttc
    46741 atctatagac aacacaagac cattaccttg tacaggctca taatattttt ccattccctg
    46801 tggtatttct cttcctgagg catcagtact tactataagc tttccaggct ttccttttaa
    46861 ttttttatca tattgcattt ctataccaga tatacctgtt gcatctgaag aagtatgtcc
    46921 caacacatat ggtgcaaaat tcccatatgg gtaatatctt tgattatctt ctgctaccca
    46981 tattccactt aatttagcat ctcttatttt acttgcctta tcatcatcta tccatctttt
    47041 tacttttaca agagccatat tttttttact tattaaagca taaatatctt tataatcttc
    47101 atccaaaatc tcagctacct tttcggcggc ttccttttta tcttctactt ccacaggttt
    47161 acaccaaaca gtatacttag ttacacttac tgctaactct ttcatatttc tatcatatat
    47221 agttcctctt ttgggttcta ttggtatatc tcttgtttgc tgttctagag cttttgtact
    47281 taaccaattt cccttcataa gttgtagata cccagtccta ataacaaggc aaaaaaataa
    47341 tgcgcatgct agaataagaa cgagtaccag ccttttctta cttatcctct ttacttttct
    47401 caaatctatt ccccctagtt atccacatct atatacttta tttgtccatc ttttggatag
    47461 tccatattga gcaattcctt agcctttagc tcaatttctt ttatcgatgt tttttcagtt
    47521 tcttttgcct ttagttcctc taatactatc tctttttttc ttaaatcttt ttgtaaataa
    47581 taaatatcgt acttcatttc tgagattttt gaataaccac atagattcaa tattattact
    47641 gcaaaagttg caatcagtaa aatgcattta gttcctattt ttttcttatt tctcttttta
    47701 taattattct tttttttatt tttatattca tttagattat gtattttata attttttttc
    47761 aaattatcac ctcgatagta tatagtttaa attttcctct atactatatt tgttgttaat
    47821 catatttctt cctctaaaat ttcatcgcta aattaataca ctattgcaca atctaattgt
    47881 gtttttttct atacacaaca aaaacctata aattcactta tacttttata tgaatctata
    47941 ggttagatat taatttttat ttatttttat cacttctaat attttcagat aatttcttcc
    48001 ataaatataa tatgtaacta actatctact ttctaatttc tccattatat tacttaatat
    48061 catctatatc tatattttta tacctaaatt ttcattatat atctcattag caaaaaacat
    48121 ttcttatagt gttaattatt ttgtaattac tttaccagtg caacaaaata tacgatactt
    48181 tttaattaat tataacaaat cttattttat acataagatt actctttaac tttataaatt
    48241 atattttttc tgctactctt agcttagcac ttcttgaacg tggatttgct tctacttctt
    48301 cctcactagg taatataggt tttctagtta ttatttttac ctcagattct ttgtcacatt
    48361 ggcatatagg taaatgttgt ggacatatgc aatctgatgc tagatactta aatgcatttt
    48421 tcactattct atcttctaat gaatgaaatg ttattataca tattcttcca ccttcattca
    48481 ttatagaaga agcatcattt atcatctttg taattactcc aagttcatta ttcacttcta
    48541 ttcgtattgc ctgaaaagtt cttttagctg ggtgaggacc atctattctg gcttttttag
    48601 ggatagcttt tttaattata tctactaact ctcctgtagt ttctattgtt ttgtttgctc
    48661 tttcttcaac tataaattta gctatacgtt tagcccagtt gtcttcacca taatctttta
    48721 ttatcttagt taattcatct tctgtgtaag tatttacaac gtcatatgca gaaaactcac
    48781 acctaacatc cattctcata tcgagtggtg catcttgcat ataagaaaat cctctatcag
    48841 cttcatcaag ttgatgagat gaaactccta aatcagctaa tacaccatca atcttgtaaa
    48901 ctcctatttt ttctaactcc tcttttatat tttcaaaatt gctatgaaca aacttcactc
    48961 taccttcata ttcactcaat ctctcttttg ctgtgtttat agcattttta tcttggtcaa
    49021 accctataaa taatccctta tctgaaagtt tttttactat ttccttagaa tgtcctgctc
    49081 ctcccatagt acagtcaaca tacactccat ctggctttat atttaaattc tctatacact
    49141 catttaaaag aactgataca tgatgaaatt ccatagttac ctcccttaaa ttcacttttt
    49201 aaactattct tcactaatat tgtttttatt tttctttgat aaataaatat gtgcaattag
    49261 accaccaata actccaatta gacttataac ttgtgccatt ctaagtggac ctaacattaa
    49321 actgtctgtt cttaatccct ctataaaaaa ccttcctatt gaatataaag ttatataagt
    49381 aactataact tgaccttcat attttttatt ttttctaaat agtaataaaa ctataaatat
    49441 tccaaagtcc catatggatt catacaaaaa agttgggtgt acctttactc catcaaccat
    49501 tattccccaa ggtaaattag tagcacctcc atgtgcttct ccattaataa aatttcccca
    49561 tcttccaata gcttgtgcta agggcattcc aagtataact gtatcagcca tttttaagaa
    49621 gttaatattt ttaatcttag tgtatatata accagctaat attccaccaa ttaaccctcc
    49681 atgtatagca agtccaccac ctctaaaatt aaaaatttga gacatatttt gagcatagta
    49741 actccaattg aatacaacat aatagattct tgcacagatt aatccagctg gaattgctat
    49801 tatagctata tttaatacat catcttcttt aattcccact ctttttgatt cttttattgc
    49861 tattagagtt cctaaaatca taccacatgc cataagtatt ccataccaca tgatgtctat
    49921 gccaaacagt gtaaatgcta ctctatccat aacgtcacct ctttttatta attaaaaata
    49981 tttccaaaga aatatcctat aattacaatt aattgtaatt atactaaatt atgataacac
    50041 attaatgtta attctacaaa aaatattaaa atttattcta tagataccta tactatatta
    50101 taccaatcta attgatataa aattctttga actgaacctc acatgactaa aatcacaagt
    50161 gtgcatagat attttttaat caaaaagatt gatgtatgta tacaccaatc ttttatatat
    50221 cttatctata actcttaaat tttttaactc aacttctata aagatatttc ataaatttgt
    50281 tttactaaaa taaacattca aaaacataaa ctaacattta actatttatt cttattatga
    50341 ttaaatttct atttaggctc tacaatagaa ataacacaat actcctcttt aaaatgttct
    50401 tttaatcttt cttcaacttc ctcaaaagta atatctttaa taacatctaa ataatccaat
    50461 aaatttatat ccttaaacac ataagatata aaactatttc ctataaagtt tatagaatca
    50521 aagcacttaa taaatgaacc tatttttttc tttttagttc tatcaaactc ttcttttgat
    50581 aagccctctt tttttgattt ttctatataa tcaagaatta ttttttttac ttttttaggt
    50641 tctttagaat ctcctgctat tatgctaaaa gcataatcta cttgagatga aaatccagct
    50701 ccaaaattgt catttattaa accttgcata tataaatctt cataaagctt acttcctttt
    50761 ttaaataaca ttcctacaag tatatcagtt acaatctctt tacgtaaaag ttcttttcct
    50821 tttaaaccaa cattactatc tttaaaacct atgttgaaca taggcataga tatagggaat
    50881 ttttctatga cctctttttc ttttacactt tttggttctt ctggataaaa cctttctata
    50941 ctcttagaga gtttatctac tttgtaattg tttgattttt tagttacatc tataactttt
    51001 tctacatcta ggtcaccaac aacaaataga gccatatttc ctggattata aaaagtgttg
    51061 taacatttat ataactcttc tttagttatt ttatatatac tatcgactgt acctgctata
    51121 tcaattctag caggataatt tacatacatt gcctttaaac aattaaagta tacattccaa
    51181 tcagggtcat cattatacat ttttatctct tgtgctatta tacctttttc cttttcaaca
    51241 ttttcgtctg taaaataagg tgtttgaaca tagtcaatta gatgttctaa actctcataa
    51301 aaattttcag tagcagaaaa taagtatgct gtcattgtaa aattagtaaa tgcatttgca
    51361 tttactccta atttagaaaa tttatcaaat gcatctcctc catcaggttg ctcaaacatc
    51421 ttatgctcta gaaaatgtgc aataccttca ttcactctaa tttttttatc ttctccaagt
    51481 ggtacaaact ctaaatcatt cgaaccataa ttagtagcca aaatggcata ctttttcata
    51541 aaaccccttt taggcataaa atatacatct aatccatttt gcaatttctc ataataaact
    51601 tcttctttca atatatcatt aactattttt tccatagaca tctcctccat taatttctca
    51661 agaagtatac agtatcaagt tctatatttt ttatagcttc aactatatct ttttttgtaa
    51721 ccttttctat actagatatt atgtcttgta cttcagaatt tgtctttgcc atagactgag
    51781 agaaagcaaa gtcagacata ccacctatat tatcagttat agatttcata gaattaacta
    51841 aagcaagttt actgttttct aattcttcat cagatatgtc acctgctttt acactttcta
    51901 cttgttcttt tatcaattcc acggctttat cataatcttt agtttctata ccagatgata
    51961 taaacaggat acttttatac ttctctattg aagagaatat atagtaacat aaactttctt
    52021 tttctcttac attaacaaat aatttagagt gtggaccacc acctaataca ttgcttccaa
    52081 ctactaaagc ataatatcta tctgtatctg cataatccac atttgctcta taacccataa
    52141 ctaacttacc ttgagttatt tccatttgtt catctacaac ctttacctca tcaacatttt
    52201 ttataaaatc tgctcttggt atatctataa tttcttctct ttcaaatttt agatttttac
    52261 ttattatatc tacaacttta tcttcatcaa aattaccttc tacaactata tctataggtg
    52321 atgttttaag tatgttttta taatgttcat ataactcttt tgaagttata ctatctattt
    52381 catcttcata accaaattca cttatactat atctctcacc tttacacata gcctcaatac
    52441 atttatcttg tgcatattcc tttttatcat ttattattga ttgtatcttt tctcttaaat
    52501 tctctttttc aatatttaaa tattcttctt taaatccgcc atctacaaca agcgtattat
    52561 ttatcacttc attaaaaaat tctactactt cttcaaatat actctcatct aaatactttt
    52621 cacttatgtt aattacttta aaactcaata cttgacgttc tccacgtttt acagcatcag
    52681 ctcccataga tgaaccatat aaatcatcta atttattgga tattgctcta gcactaggat
    52741 atttggcgct tccacttgct attattgatg gtattagagc attttttgta gtttcttttt
    52801 catccaatag tctctgaaca tataaactta taagattcga tttaaacttt tctgttttta
    52861 tcaaagtaag attaatatta ttacctaaat ttattatttt tttagtatta accatatgta
    52921 cctcctattt ttatttaaac atcaatttta aaattgaaat ttatttattt tttaatttca
    52981 tatactcaca tataaaaacc ttctatttaa ttatatcctt tttattattt tc
//
LOCUS       DAMKOJ010000020        52926 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000020 DAMKOJ010000000
VERSION     DAMKOJ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52926
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.021"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(205..1008)
                     /gene="proC"
                     /locus_tag="PC592_001279"
     CDS             complement(205..1008)
                     /gene="proC"
                     /locus_tag="PC592_001279"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF4055273.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAKDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVANSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKAMFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(1333..3702)
                     /locus_tag="PC592_001280"
     CDS             complement(1333..3702)
                     /locus_tag="PC592_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF4055274.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFKSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(3707..4615)
                     /locus_tag="PC592_001281"
     CDS             complement(3707..4615)
                     /locus_tag="PC592_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF4055275.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSRCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIDKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKYADLFLYDIKLIDEEKHIKFTGKSNDLILKNVKVLSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTEIGG"
     gene            complement(4960..6039)
                     /locus_tag="PC592_001282"
     CDS             complement(4960..6039)
                     /locus_tag="PC592_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF4055276.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVGKSTGSSTP
                     IIVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTNNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTTMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASKAEGLGFAIPINTAKSIVEEVIKTGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TLSKGASTKITVNRGGKAVTINVNF"
     gene            complement(6194..7543)
                     /locus_tag="PC592_001283"
     CDS             complement(6194..7543)
                     /locus_tag="PC592_001283"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF4055277.1"
                     /translation="MRKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDFLLVIGIGGSYLGSRAAIDMVSHSFRNR
                     LKKEQRNAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDSSKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKNNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITINSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            complement(7807..9435)
                     /locus_tag="PC592_001284"
     CDS             complement(7807..9435)
                     /locus_tag="PC592_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF4055278.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPIALGVGIILYLFGNNPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPILGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPIVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNFIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            complement(9558..11162)
                     /locus_tag="PC592_001285"
     CDS             complement(9558..11162)
                     /locus_tag="PC592_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055279.1"
                     /translation="MLRISNVKLGIDKDISLLKDIVLKKLRIKEKNLIKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILKSKIKDVTKIKEIRYINVPMGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVVINDTEKIDTDTIILAVGHSARDTYEMLYSRGVKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASTSNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGNVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSVRNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            complement(11210..11527)
                     /locus_tag="PC592_001286"
     CDS             complement(11210..11527)
                     /locus_tag="PC592_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055280.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGNEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            complement(11532..11897)
                     /locus_tag="PC592_001287"
     CDS             complement(11532..11897)
                     /locus_tag="PC592_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055281.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            complement(11978..13015)
                     /locus_tag="PC592_001288"
     CDS             complement(11978..13015)
                     /locus_tag="PC592_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF4055282.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSLFESYVSIYEVKEISAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKKERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            complement(13268..13852)
                     /locus_tag="PC592_001289"
     CDS             complement(13268..13852)
                     /locus_tag="PC592_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055283.1"
                     /translation="MRLNNREKNLLKILLILVIMVASDIVVNYLEENLTSLKNEKQNI
                     INKINNQDNYQIKGNKHIDDKYIESVELNENEELKNNFNNSFLDKKTNKDIVLLVENE
                     LKNIVNIEYINQESSLDNHNKKQVNLEIKVNGELENVLKFEDVMKKLRLNNKLEKIEI
                     NKLKVNNFDAQNILSEYKQEKDNIVECKMTVRVT"
     gene            complement(13867..14310)
                     /locus_tag="PC592_001290"
     CDS             complement(13867..14310)
                     /locus_tag="PC592_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055284.1"
                     /translation="MKVDKTINFLNGFKKTKSCNKVYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKHTISTTDKTREKFSKIKLNEIKKIYETIGINSITRIWIDK
                     NKLEIEGVCSDLDVLDNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            complement(14311..15183)
                     /locus_tag="PC592_001291"
     CDS             complement(14311..15183)
                     /locus_tag="PC592_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF4055285.1"
                     /translation="MATIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFNIK
                     NDSNSIEKIKYIEDVVRFVKEEIDKSKISYKNLYFNIQIQDIVIRNVEVLDTKKKRDI
                     LSMIEFEITQYIPINISNYSIKYKVINSINDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIEETYLLSKERK
                     SYEFIKRLLRDFKYIYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDTDLE
                     DNSINYISSIGMII"
     gene            complement(15237..15587)
                     /locus_tag="PC592_001292"
     CDS             complement(15237..15587)
                     /locus_tag="PC592_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF4055286.1"
                     /translation="MINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKLNAD
                     YTNAANIVTAASMAINDDENIIDSLSVEALKEKGYLNTVPVPQSTSGKFELVINDNGT
                     DISVNINSKQFYPK"
     gene            complement(15641..16726)
                     /locus_tag="PC592_001293"
     CDS             complement(15641..16726)
                     /locus_tag="PC592_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF4055287.1"
                     /translation="MRLSKNIFCNLEKFYLVLNRISDKEIRVICKEIGILMESGCEIT
                     KIFEIIESQSSKKVKNLLNIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKIKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTSNG
                     IEPPLITRVLMGISTVVTNNLAYLIFSFILFSIGSIYFFITNDNIKKLTNSLKFKVPF
                     VKRINQLVATTRFSRALSILISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMTNTGEESGKLDKSLDVINKFYENELNNKIEQIMKFIEPV
                     LIVFMGLIIGIFVLAMVVPMFDAITSF"
     gene            complement(16897..18276)
                     /locus_tag="PC592_001294"
     CDS             complement(16897..18276)
                     /locus_tag="PC592_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF4055288.1"
                     /translation="MIKIILEENSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVVKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDDFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            complement(18269..18949)
                     /locus_tag="PC592_001295"
     CDS             complement(18269..18949)
                     /locus_tag="PC592_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF4055289.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKGKLDKEIDSMKKNQKNSEKISQIETLRDSLSYSDMKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKLNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(19552..20631)
                     /locus_tag="PC592_001296"
     CDS             complement(19552..20631)
                     /locus_tag="PC592_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4055290.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNRQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVNKVY
                     YLAGEIGTGKTTLLNKVYNKAIEKGLNVEVYHYPLIPEKIETILLTDLDIGITISTNF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDNLVKRILKYEENL"
     regulatory      20917..21032
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21207..22577
                     /locus_tag="PC592_001297"
     CDS             21207..22577
                     /locus_tag="PC592_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4055291.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPTNEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQSKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGIIALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGSVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATVRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNKSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     gene            complement(22841..23452)
                     /locus_tag="PC592_001298"
     CDS             complement(22841..23452)
                     /locus_tag="PC592_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF4055292.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23442..25805)
                     /gene="lon"
                     /locus_tag="PC592_001299"
     CDS             complement(23442..25805)
                     /gene="lon"
                     /locus_tag="PC592_001299"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF4055293.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGKVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVISKSDLEAYLGKDMFKYQLAEVNPQIGLVNGLAWTAVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPDFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            25985..26497
                     /locus_tag="PC592_001300"
     CDS             25985..26497
                     /locus_tag="PC592_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF4055294.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            26485..27012
                     /locus_tag="PC592_001301"
     CDS             26485..27012
                     /locus_tag="PC592_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF4055295.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATVGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(27081..28331)
                     /gene="clpX"
                     /locus_tag="PC592_001302"
     CDS             complement(27081..28331)
                     /gene="clpX"
                     /locus_tag="PC592_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF4055296.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(28350..28934)
                     /gene="clpP"
                     /locus_tag="PC592_001303"
     CDS             complement(28350..28934)
                     /gene="clpP"
                     /locus_tag="PC592_001303"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF4055297.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(29084..30370)
                     /locus_tag="PC592_001304"
     CDS             complement(29084..30370)
                     /locus_tag="PC592_001304"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF4055298.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(30564..31034)
                     /locus_tag="PC592_001305"
     CDS             complement(30564..31034)
                     /locus_tag="PC592_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF4055299.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTHMLEKKATEIDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDNINIEEIRI"
     gene            complement(31034..32383)
                     /gene="rph"
                     /locus_tag="PC592_001306"
     CDS             complement(31034..32383)
                     /gene="rph"
                     /locus_tag="PC592_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF4055300.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTVKEMPITNFV
                     SAISVGIVNGTHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRTDLNLL
                     LELGEKGNKELIRLQKEALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIDIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            complement(32542..34566)
                     /gene="ligA"
                     /locus_tag="PC592_001307"
     CDS             complement(32542..34566)
                     /gene="ligA"
                     /locus_tag="PC592_001307"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF4055301.1"
                     /translation="MSIKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEDYDLESHSDSLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLEYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVELERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDDVMSATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLAKANDLGIKVIDEERFLELLKLSSKDEVKAILES"
     gene            complement(34753..35691)
                     /locus_tag="PC592_001308"
     CDS             complement(34753..35691)
                     /locus_tag="PC592_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF4055302.1"
                     /translation="MKVLFTINYGKEKFDKIRDLGYDVIHYSEDIIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGLE
                     IWGVNTAGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECIEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYILENKPVDNVVDISRGY"
     gene            complement(35793..36215)
                     /locus_tag="PC592_001309"
     CDS             complement(35793..36215)
                     /locus_tag="PC592_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF4055303.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGDNIIRDILDGNISSECENGIKSKSVIFNNAPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            36403..36981
                     /locus_tag="PC592_001310"
                     /pseudo
     CDS             36403..36981
                     /locus_tag="PC592_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            37308..37580
                     /locus_tag="PC592_001311"
     CDS             37308..37580
                     /locus_tag="PC592_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF4055304.1"
                     /translation="MQYLLIIIIGLLLFIEVDKLKKQVKSQQKQIDTLCEQTGNNQLA
                     TYHISDEDKELILHLKNSGKDVEAVKKVREITAMELEEAKQYVDSL"
     gene            37615..37833
                     /locus_tag="PC592_001312"
     CDS             37615..37833
                     /locus_tag="PC592_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HDF4055305.1"
                     /translation="MDNGGVQMDKRHWFLLGYLIIPVCFFVAVIVVGLLRSHSLIEIY
                     NDGLGITALYYLLLSLFVYIRWQYFSDK"
     gene            37854..38039
                     /locus_tag="PC592_001313"
     CDS             37854..38039
                     /locus_tag="PC592_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HDF4055306.1"
                     /translation="MYIIYTVLAAIVGMALVVTVDMGITKIFDKKSIFQKNYIKMPLS
                     YFIGIFVFLLIVRLIFS"
     gene            complement(38105..38413)
                     /locus_tag="PC592_001314"
     CDS             complement(38105..38413)
                     /locus_tag="PC592_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006426016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055307.1"
                     /translation="MKKKLLFATIILVLLAGILYYISLPDYLVFNSMSFSNGANRDTE
                     LQVIVYQYWNTDEVVAEIEAEHNQINGTPTTLIINLYHSKWSFHNGYEPFYSTIINYD
                     "
     gene            38527..38742
                     /locus_tag="PC592_001315"
     CDS             38527..38742
                     /locus_tag="PC592_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055308.1"
                     /translation="MKYGHLELHIEELLKEKGISKNTICKELDIPRSNFNRYCRNEFQ
                     RLDAQLICKLCSYLDCGIEELIEYVKE"
     gene            complement(38935..39618)
                     /locus_tag="PC592_001316"
     CDS             complement(38935..39618)
                     /locus_tag="PC592_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4055309.1"
                     /translation="MNTIAERIKFAMKAKNKKQVDIVKDTGISKGAFSSYLSGQYNPK
                     ADKMELIADSLDVDLRWLYGQNVPMEHTSQNDNALQYVFYNNSCSEYLLDDLDDIYIA
                     MMTQYAALIPRFYVLVNRAGNAMHILPLFLKEDSSQFYECPSDFFYSDRHTIFTRDFE
                     SIHMVLTTATIYYYGIDTKTYEPKVTMLSYSQADDCFHINNGIQGGHIKAFEKELMKE
                     ALYLKHNDQ"
     gene            39867..40196
                     /locus_tag="PC592_001317"
     CDS             39867..40196
                     /locus_tag="PC592_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055310.1"
                     /translation="MQITLTKEQVKEAFGELRFMGADNCYRYDKDSKKKTEEVEALKL
                     HLGSMKLGNSVDIRLEATELPKIEPYAVVELEESVYAPYVQRGNFPVLVEKITCKGIR
                     PVPNKNM"
     gene            40255..41364
                     /locus_tag="PC592_001318"
     CDS             40255..41364
                     /locus_tag="PC592_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF4055311.1"
                     /translation="MATPLQIGGMGNLEERSGSFLPELPYTNRGVIRQKEALSALIDW
                     CQITIKEVPLEAVIEDVLRIPLELMTVTGYEKGIAGHEVVAIFDNIKVLKPTGNAQYQ
                     GFQILMSGKGCRNYENFLQLNEETWFDFLNRVCQYHINVPRIDLAIDDRKPYLSIPDL
                     IVRTKEGLLSTKLREIDFHDSGELKEEVFQSKGGSLYLGSSASNLRLVFYEKGYEQNK
                     KYGTELDENWNRYELRFRQEMAVSVVQELLRYRDVAGLAMEVLNSKMRFLEKPTDSMT
                     TRKRLYPTYQAWAELMKDIGKVKLTMQPQKKSLQKVWKWLEKYVAPSLKLFAEVGKIE
                     QRDYIGNLVKNGEMNIAQKQLYDDYIKARKLDERG"
     gene            41384..41566
                     /locus_tag="PC592_001319"
     CDS             41384..41566
                     /locus_tag="PC592_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4055312.1"
                     /translation="MNLKEVSEYLGIGETKTRELLRDRNCPFSMKIGYRWYANKKILD
                     KWVQEQSEKKGGNYSI"
     gene            41652..42926
                     /locus_tag="PC592_001320"
     CDS             41652..42926
                     /locus_tag="PC592_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4055313.1"
                     /translation="MGKSLKGKELGAGLYQRKDGKYCGRFYDRFGIRRYVYGKTISET
                     KEKLNTAMYEDKMEMNVADNTVTLDEWYQKWLEIYKYKVIAPSTRVQYESIYKKHIQT
                     DFGHMKLKDIQPLQIRGKLVNLDKKGFGYETQNKVRILLLDMFNKAVADNVAMKNPVR
                     NIKVVRDEEKEPRVLSTEEQSAFFDTCKGTFYDNLFNVAISTGLRPGELYALEAEDLD
                     FEKKVIHITKSLSYQKFEGDTGKTFHMGKTKTKSSYRDVPMNRRCEIALKKQLLQKRV
                     VSGRNGAKTLKGFENLIFTTKYDTPLNAQIYADAIKVIVEQINLMREELEQFETFSGH
                     CFRHTFATRCFEAGIQPKTVQKYLGHATLQMTMDLYTHVLENHLSDEMDKLDSRLEMI
                     ELSSDDLAEQRFEREYRKQNEVLSSDKLIRIG"
     gene            43035..43745
                     /locus_tag="PC592_001321"
                     /pseudo
     CDS             43035..43745
                     /locus_tag="PC592_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(43821..44336)
                     /locus_tag="PC592_001322"
     CDS             complement(43821..44336)
                     /locus_tag="PC592_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF4055314.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(44336..45712)
                     /locus_tag="PC592_001323"
     CDS             complement(44336..45712)
                     /locus_tag="PC592_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF4055315.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(45737..46288)
                     /locus_tag="PC592_001324"
     CDS             complement(45737..46288)
                     /locus_tag="PC592_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF4055316.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIIKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYQDGKEVEQVILDENKKIAYKCDLCKDSEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(46509..47342)
                     /gene="fdhD"
                     /locus_tag="PC592_001325"
     CDS             complement(46509..47342)
                     /gene="fdhD"
                     /locus_tag="PC592_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF4055317.1"
                     /translation="MNNIYSKTKLQQNSKDKVFENSYSLVEHKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNNKYINTFLCTPSNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIHEKQKNQNEQIIFLNSLDYITCAPVESNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSIFNFDKRIVTCEDVARHNAMDKAIGFCVLNDIALKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(47391..49535)
                     /gene="fdhF"
                     /locus_tag="PC592_001326"
     CDS             complement(47391..49535)
                     /gene="fdhF"
                     /locus_tag="PC592_001326"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(49119..49121),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDF4055318.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYAASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIEAQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAKKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYKSLKDKMTATNI"
     gene            complement(49786..50844)
                     /locus_tag="PC592_001327"
     CDS             complement(49786..50844)
                     /locus_tag="PC592_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF4055319.1"
                     /translation="MDRLKSIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPQKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            complement(51055..51714)
                     /gene="cprR"
                     /locus_tag="PC592_001328"
     CDS             complement(51055..51714)
                     /gene="cprR"
                     /locus_tag="PC592_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF4055320.1"
                     /translation="MSKILVIDDELDVLKLIENVLKRDGHEVKVISDIENAMDIEFNS
                     FNLIILDVMMPKMDGFEVCKAIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVLIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHVKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            52024..52653
                     /locus_tag="PC592_001329"
     CDS             52024..52653
                     /locus_tag="PC592_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HDF4055321.1"
                     /translation="MDEKIRSSNYNVPFDYARKKFKELDPHTISNLSNISFNNDSNKF
                     ILNFFDRQYIIDYPSGEVWNDDGSICKNFELKILIIRYLTNAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLSRLSEVFTCQIDKYKLVMENMGAEKVDMGDLAYKFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIIYYFNAEDLAVVPDTAIDAILNKINQL"
BASE COUNT        16465 a         9230 c         6332 g        20899 t
ORIGIN      
        1 ttatttttcc acaataatgt atctcaaata tagttaaaaa tatatctatt taattattaa
       61 tatttaagta ataaagtctc actcaatcat taaattcctt tttatagcaa attactctta
      121 tttcacttat gcttaataca tttatagata taaatactaa aaaagcaatt caataaacca
      181 tatgataaac ctaatttatg tctgttattt gctcatatct ttagacttat ctatacaagc
      241 aacaatagat tttataactg ccgctctaaa tccttcttct tctaatacct taacagcttc
      301 tatagtagtt cctgctggag aacaaaccat atcttttaac tcacctggat gttttccagt
      361 ttcaagaacc atcttagctg accccattac tgcttgagat gcaaatttat aagcttgttg
      421 tcttggcatt ccagctaata ctgctgcatc tgccatagcc tctataaaca taaatacata
      481 tgcaggagaa gagccactaa tacctgtaac tgtatccatt aaatattctg atactatctc
      541 tgcctcacca aaagattcaa acatagcctt aatcatattt aactcttcat ctgttacatt
      601 actattttta caaagagctg acattccttc cccaacaagg gctggagtat taggcattac
      661 tcttactatt tttttatctg agcctataaa actttccaga ctttctatag ttttacctgc
      721 tgctatagat actattattt tatttgcatc tattaattct ttaagtggag ttaaagcctt
      781 ttcgcatata ttaggtttaa gtgctactat taccacatca gaatttgcaa cagctacctt
      841 tgagtcagtt gtagtattta ctccaaattc ttcttttact ttatctaagg caacttggct
      901 taagtctgat acagttatgt cttttgcttt tactaatcct gactgtacta taccacctat
      961 cattgcactt cccatattac ctgaaccaat aaatcctaaa gttttcatat caaatctcct
     1021 tttttctatt agttttattt taaagtagct aaattaactt tattttaact gcttaaaatt
     1081 atcttatttt tataaaatat aaccttatta taattataac aaattacttt tttgtatgta
     1141 ttacttacta atatatgtat gatttattaa atataaattt aacgattttt tcattaaact
     1201 taacgagcta acttcctgtt tagaaagtta gctcataatt aatctaaaat ttttaaaata
     1261 taatcaaacc atttatactt tattatatca gttacgattt tatatagtaa gaagttttat
     1321 ttgcaagcaa tcctagaatg tttgctcagt tcttcctatt atctcatctt gtagtgttct
     1381 acttaaatta ttgaaatggt cactatatcc tgcaactcta actattaaat ctttataatc
     1441 ctgaggattt ttttgagcct ctaacagtac atttttatca aatacattaa attgtatatg
     1501 atgaccatcc atattaaagt atgctctcac tagattagcc atattgtcta accctttttc
     1561 tccttgaact actgatgggg caaatctttg atttaatagt gttccaccag tttttatgtg
     1621 gtccatctta gcacaagatt ttataactgc tgtaggcccg ttagtatctc cacctttttc
     1681 aggtgaaatt ccctctgaaa ctggttttgc acaaagtcta ccatttggac ttgctcccat
     1741 aatttctcca aagtatatat gacaagttgt tggtaacata tctactctgt attctccacc
     1801 acaaacagtt ggtctaccag ttacctcatt gtaatatgca ttgaatatct cttgcattat
     1861 ctcatcagca taatcatcat catttccata tttaggagtc ttatttgaaa ctaaattaag
     1921 tatagcttcg tatccttcaa aattagcatc aagtgcttta agtaatgtgt ccatatcaaa
     1981 ttttttctta tcaaatacat tatattttat tgctgtcaaa ctatctgtta tagttcctat
     2041 accaacacct tgtatatatc tagtgttgta tcttgctcca cctctttggt aatccttgcc
     2101 tttttctata caatcatcaa ctattgtaga cataagtgga caaggcatgt gttttgcaca
     2161 tatattttct atcacagcat ttccttctat ttttatgtca atcatataat gtaattgctt
     2221 tttaaatgct tcaaatagtt cctcataaga tttgaaattt ctagggtctc cagtttcaat
     2281 acctatttgt tttttactaa ttgggtcata tccattattt aatgttaatt caagtatttt
     2341 tggaatgttc atatatccag ttaaaacata tgcttcttta ccaaaacatc cagtttcaac
     2401 acaaccacta gttccaccaa gtcttgcatc ttctatagtt tttccagctt ccataagctc
     2461 ttgaactatt gcttcagtat tataaaatgc tggttgaccc catccttttc ttgatatttc
     2521 acaagctctc tttaggaatt tttgaggagt ctttttactt atttgaacat ttgaactagg
     2581 ttgtatcaat ttcatttcat ccataacatc aagtattata taactaactt cattaacacc
     2641 atcttgacca tctggattta ttccaccagt gtttatattt gcaaaatctg tatatgtgct
     2701 actttctttt aatgttatac caacttttgg tggtgctggt tgattgttaa atttaaccca
     2761 taaacattca agtaattctt gtgctctatc tctatctagt attccatttt ctacatctct
     2821 ttcatagaaa ggatttagat gctggtcaag tcttcctgga gtaaaagcat cccatatatt
     2881 aagttcagta gtaaccccta tatgaacaaa ccaatacatt tgtatagctt gatgataagt
     2941 ttctggtttg tgagctggta caacatcaca agtttcagca attagtaata aatctttttt
     3001 cttagcttca tctgtttctt cttctgccat ttgtcttgct ttctcagcat atcttttacc
     3061 taatataacc attgcatcac aagctattgc catagcttct aaatcagctt ttttattata
     3121 tgcatctaaa tcattaagaa aatctagctc ttttaatctt gcttctatat ctttctttaa
     3181 atctaaaaat ccttttttgt atattgtatc tccacaaact gtatgtcctg gagctctttg
     3241 ctccataaac tctgtaaaca tacctgcttc atatgctgct aaccactcag gtgtcattgc
     3301 atttattatc ttatctcttg tttgtctctt tttccaaaaa ggaattattt cttctttatg
     3361 tatttttcta gcttcttcag atacgctaaa atttattata tctctattgt gcattacttc
     3421 taaatcttcc attgtatgac aacaaatttc tggatatgtt ggtgctccat taggagaatc
     3481 acctttttca cctactatta attctccatc atttatgcta agagttctat tctcaatata
     3541 atgcttaaat gataaagcac gaagtacagg aatctctaca cttccctcat attttttata
     3601 agcttctgtc ataagtactg ctctttcaat agatatgtgt ggttctgcat taatactttc
     3661 ttctcttaat tttttagttc tctcaaaagt tcctcttgcc attttattac cctccaatct
     3721 cagtattgaa attacttgct tcaaaaagtc tttttatttc ctctaatttt tcttctgatg
     3781 gtctttgtag ttcttctcct tcatactttt tataaatctt atcatactta tgtttaccaa
     3841 tattatgata tggaagaaga ctcactgctt gtatattcaa aggttttaaa aactctatca
     3901 tttttttaac ctctaaattt tcatcatcta catttactcc tacaattaat ggtattctta
     3961 tatttatgtt agcccctaat tcacttaaaa ccttaacatt tttcagtatt aagtcatttg
     4021 attttcctgt aaattttatg tgcttctctt catcaataag cttaatatca tataaaaaca
     4081 aatctgcata tttagcaact ctttcataat tttctgactt tgcatagcca catgtatcaa
     4141 ttgctacatg gattcccttt gatttgcaca tatttattac tccacaaatg aagtccatat
     4201 cttgagccat tacttctcca cctgacagag ttactccacc acctgattct tcatagaaaa
     4261 ttctatcctt gtctatctct ttaaccaagt ctcttacaga atactcttga ccaacaatct
     4321 cccttgcatt gtttacacaa tagtctaagc aagtttcaca aaattcacac ttatcttggt
     4381 ctaggcatat ttttgtttca cctttgtaaa ttgccttatg agggcatata tttatacatg
     4441 cttcacatct tgaacatctt tcttcattat acaaaacttg ttttgtatat gtttgactct
     4501 ctggattatg acaccaaaca cattcaagtg gacacccttt aaaaaatact gtgcttctta
     4561 tccctggtcc atcatgtatg ctgcattttt gtaagtttat aactaatgga ttcataattt
     4621 ttcaccccta aataatatcc attccatttt ttcattttta tgtaatttat cttcatagaa
     4681 tatacctatg aaaagcattt ctacaattac ataatactat acttgttatt attttgtcta
     4741 tatcttttta gtaatattaa aaaattttat tttattatga tatttatatt gtttttgtaa
     4801 attaaattta aatatttatt aaatttattt ttataagaaa atatagcaat aagccataaa
     4861 caatacatca ttttaattaa tttagatgta tatactataa aaattaaata aaaatagaga
     4921 ctacacttta ccatgtagtc tctatttttc tggtcatatt tagaaattta catttattgt
     4981 tactgctttt ccacctctat ttactgttat ttttgtacta gctccttttg ataaggtata
     5041 caacttttta tttaaatcat tcatacctgt tatgtctgtg tctcctactt tagttataat
     5101 atctcctacc tttacaccag ctttttctgc tgatgaacca gatattactt cagcaacata
     5161 aacaccttta tcagtactta attttgtacc tgttgctgct tcataatttg atacatctgt
     5221 accttttata cctaaagtta ctttttcata ttttccagtt tttattactt cttcaactat
     5281 actcttagct gtattgattg gaattgcaaa tcctaatcct tctgctttag aagcttttgc
     5341 tgtatttata ccaattactt gacctttttg atttaataat ggccctccac tatttcctgc
     5401 atttatactt gcatcagttt gtaacaaacc agtcatagta gttttttctg tttgtatagt
     5461 tctatctaaa ccacttatta taccttgagt aactgttttt tggaaatcca acccaagagg
     5521 attacctatt gctattgaaa tatctccaac ttttacttta tcactatcag caaattctgc
     5581 tggtgttagc ccagttttat caaccttaac tatagctaaa tcaagttgtt ggtcaaacca
     5641 tactacttta cctgaagttg ttgaaccatc attgaataat acatttacac ttgtagcttg
     5701 accatctgat ataacatgag aattagtaag tatatatcca tttgaatcaa ctatgattcc
     5761 agttcctaca ccctgtgttt cagttggtat tgcaaacata ttattagtat caacactagt
     5821 tgttgtaata cctacaacag atggtgtagc tttttctgca actgcttgat aaatattttg
     5881 actcttacca tcatcattta caattattgg tgtagaactt cctgtagatt tgcctactaa
     5941 attatcctta actaaaatta ttgttagaaa actactaagt attgaactta ttatagcaac
     6001 taatattact aaacttatcc ctttctttct tcttgacatc tcataccact ccctatctaa
     6061 tataatataa attatcaaaa tatatttttc ccaatttttc ataaaaaaaa tgaaatcatc
     6121 tattttgagt aaactccttt tcgatgattt cattatatta ttttaatctt aattaaacct
     6181 taactattta aaattattta agtctttttt ctagctcttc cttttctttt tcataacctg
     6241 gttttcctag taaagcaaac atgtttttct tgtaagcttc tactcccggt tggtcaaatg
     6301 gattaactcc caataaatat ccacttattc cacaagcctt ttcaaagaaa tacactaagt
     6361 atccaaaatt atactcatct aattgaggta tatttattac taaattaggt acttttccat
     6421 ctgtatgagc caatagagtt ccttcaaaag ctttatgatt tacaaaatct acagtcttcc
     6481 ctgctagata atttaaacca tctaagtcta cttcctctga atttatagtt atatttctct
     6541 tacaattttc aacattaagt actgtctcaa ataaaagtct ttttccatct tgtatgtatt
     6601 gacccataga atgtaaatct gttgagaaat ctacagaagc agggaataaa cctttatttt
     6661 cttttccttc actttctcca taaagctgtt tccaccactc acttacatag tgtagttgag
     6721 gttcatagtt aaccaataac tctacatctt ttccttttct atgtaaaatt gttctagcaa
     6781 cagcatatct ataactatca ttatttttta ggtcaggatt ttgaaatgct tctctagcat
     6841 catttgcacc tttcatcata gcatcaatat caagaccagc agcagcaata ggaagtaatc
     6901 caactgctgt caatacagaa aaacgaccac ctacatcatc tggtattaca aaagtctcat
     6961 atccttcttc tgtagctaac tgtctaagtg cacctttact tgaatctgtt gttgcataaa
     7021 ttctctttct tgcttcttcc ttaccatact ttttctctaa gtaatcttta aatattctaa
     7081 aagctagggc tggttctgta gtagttcctg atttagatat tacatttaca gaaatatcct
     7141 tcccttcaat tatatctaat aaatccataa tatatgttga gcttatatta tgccctacaa
     7201 aatatacttc tggagcattt ctttgctctt ttttaagtct attcctaaaa gaatgactta
     7261 ccatatctat agcagctctc gaacctaaat aagagcctcc tatacctatt accaaaagaa
     7321 aatctgagtc tgattttatc ttctcagcag atttttttat tctgtcaaac tcttctttat
     7381 cataattctt aggaaggtct atccatccta aaaaagtatt tcctaaacca gttttattat
     7441 gtaacatgtc gtgtgcaaca tctacatatg gttgcataac atctatttcg ttttgacaaa
     7501 aaaactctgt agctttacta taatcaaaat ttatttttct catttaaatc cctcttttca
     7561 gcatattcgt tttaaagaga ttataacaca aaatatgggc gtttttttta aaagtttatc
     7621 acaaaatcat acatatctca tcatttatta tcaggaaatc gattcttcta aatgctataa
     7681 ccatgtacaa ttttttaaat tttagtcaaa taaatttgca aaaaaagaaa ctctaaacgt
     7741 atcatttaaa gtttcttttt atttatattc tatttcaatt tttatattgt tctaaactaa
     7801 ctaactttaa tcattaccta atctcttcgc tataacttgt tgtgctatat tgacagcatg
     7861 gtcagatatt ctctctagat tacttattac atctaaataa ataactccat tttctatact
     7921 acatagatta ttgttcaatc tatacatatg attagctcta caagatttct ccattatatc
     7981 aacctgctct tcaattttta taaccttgca ggctaaatct acattatcag ttctcattga
     8041 ttctaatgca taagtatatg ctgaaacaac tctattatac ataacatcaa gttcagactg
     8101 tccttcttct gagaaagaaa tatttgaatc tatcgcaact tgtgataatt cagctatatt
     8161 tttagcgtgg tcaccaattc tttctatatc gttgactgta ttaaacaagg tatccacaac
     8221 ttctcttgaa tcatcatcta aaggtgcttt tgaaagttta agtaagtaat tcaaaatagc
     8281 tttctgtaaa tcattgatta atctctctct tctatatgtc ttgtctattt tttcggttga
     8341 atgttctact aaagcttcca tagatgcatt taaactttcc ttagcctttt cacccatacg
     8401 aagtgcttct tttatcgtat ttgcaagagc tatagaagga gtttctatca ttctatcgtc
     8461 tatatatttg atagtcttag tttcatcttc atctatgtca cctgctctat caggaacaag
     8521 ttttatagct agttttatga taaaatttgt aaatggtaaa agtatcaata cagatattat
     8581 attaaataat gtatgtgtat tggctatttg tcttgcaaca ttgcttgggt cccagcttgt
     8641 aaccatgctt actattggtt tattcaagaa tattaagaat atcactgttc ctaaaacatt
     8701 gaagattaga tgcatcatag ctgctcttcg tgcatttttg ttggcaccaa tactcgataa
     8761 cagtgaagtt acacatgtac caatattttg accataaaga attggtagtg ctgctgataa
     8821 tggcactaga ccttctgctg ccaatgcaac caacataccc atagatgcac ttgaactttg
     8881 tattattgct gtaatcccaa atcccaataa taatccaagt attggatatc taccaaatgt
     8941 aacaagtaag tcagtaaatc cttgatagtc tctcagtggc tctactgcca tcttcataaa
     9001 atccatacct gtaaataata taccaaaacc tataagtatt tcggctatat tttttattct
     9061 aggattattt ccaaataaat aaagtataat acctacacct aatgctattg gagccatacc
     9121 agttaagtca aaagatacca attgggctgt aacagtagtc cctatattag cacccattat
     9181 aactcctatt gcctgtttta aggtcattat tcctgcattt acgaaaccaa caaccattac
     9241 agtagtagca cttgaacttt gtattactgc tgtaactcct gtacctacca aaactcccat
     9301 aaataggtta ctagtaagta gttttattat cttttttagc tttgtcccag cagatttttg
     9361 aagaccttct cccataaggt tcataccata taagaacaga cctaatccac ccattagact
     9421 tattataatg ttcaaattat ttcctccttg taaagagatt actgtatcta aaattttata
     9481 acctattgta ttttatcaaa ttataggagt gataatgtta aattcatgtt aaatattaaa
     9541 aaatcattaa gtttatgtta aatttttgta ttattggtgt atttttgtat tattttttct
     9601 gcacatttta tgccatcaac tgctgctgtg actataccac ctgcatatcc agcgccttct
     9661 ccacatggat atagattcct aacactcact gattctaaag tattttcatc tcttactatt
     9721 cttattggtg atgatgacct agtttctacg cctgtcaaaa cagcatcata cattgcaaac
     9781 ccattcaatt ttttatcaag agatataaat gcttctctca tagtctctgt tacaaaacta
     9841 ggcaaacatt cacttaaatt tgtaagtgta tatccaggtc tatatgatgg ttcaacattt
     9901 cctaaattta aagaagtctt attatttata aaatctccaa caagctgaac tggtgcattg
     9961 taattttttc cacctaattc aaaagccaat ttttcatact tctgctggaa atgtactcct
    10021 gctagtggat tatcactctt aaaatcttct ggtgttacat ttactaaaaa tgcactatta
    10081 gcatttattt tatctcttgc atgttcactc ataccgtttg taactatttc aaaatcattt
    10141 gatgtagatg ctatgacgct acctcctgga cacatacaaa aagtatatgc tgttcttcca
    10201 tttgaaacat gctctataag tctataatcc gcagctccta atctaggatg attgtaaaag
    10261 tctttgtact gtgctttatt tattaaatct tgtggatgtt caactctagc tcctattgca
    10321 aaaggttttt gaactatttt tacgcctctt gaatataaca tttcataagt atctcttgca
    10381 ctatgcccaa cagctaatat aattgtatct gtatctattt tttcagtatc atttattact
    10441 acagattgta tagaatcatt tgatacaact atatctgtta cttttgaatt aaacctaact
    10501 tgaccaccta aacttattat ttcatttctt atatttttaa ctacattttt taatatatct
    10561 gttccaacat gtggcttatg tgagtataat atttcatctg gtgctccaaa ttgaactaac
    10621 tcttctaata cttttctaca tcttatatct tttattctag ttgtaagttt accatccgaa
    10681 aaagttcctg ctccaccttc tccaaattga acatttgaat tattttttaa ttttctagta
    10741 gtccaaaaat cacttatatc tttggttctg ctgtctacat caagacctct ttcaagtatg
    10801 attggttcat aacccatttg ggctaaaagc agacctgcaa ataaaccagc tggtccacta
    10861 ccaattacca aaggattatt ctttaatttt ttatcaccca taggtacatt tatatatctg
    10921 atttccttta tttttgttac atcttttatt tttgatttaa gtattttatt ttcatcttta
    10981 acttctacat ctacagaata aacaaattcc atttttcctt tttttctagc atctatagat
    11041 tctttatata tactatattt gattaagttt ttttctttta ttcttagctt cttaagtaca
    11101 atatctttta ataaagatat atctttatca attccaagtt ttacattaga tattcttaac
    11161 atattgtttt cctctcttag attgtaatat aaaaaagcta gggttactcc tagctttcta
    11221 caaatataac ttctatattc tcttttacta gattttctac ccaaatctca tctagcacaa
    11281 aattctttat tttgtttaca acaagtgttt tatctaaatc ttttttcaag ttttttacta
    11341 agaccattgc ttcaaccgat ttatgcaatc tttcaacata cagagaatta actttaatca
    11401 atacaaccct taattcacac acatataact tttcattacc taaggtgatt tcatcatcat
    11461 attcgtatac actaaattca tatgtatttt cataaggtgt tatattttct attcctatat
    11521 aatccattta tttatccttt tttagttata agacctctta taaccttcat gttattaaac
    11581 accttttcta agaagttctc tgcttcttca ttgtctaaaa ggtttatttc aaggttttcg
    11641 ttttctacaa tacctttaga tttacagtac tctttagcaa tatttattag ttcatttttt
    11701 ttatccatag ataaatcaaa ctctttatag tctattatta tatattgttt ggtatcaggt
    11761 gatacaccat tattatatcc tatttctata tgataaataa ctgcatatat ttcttctccg
    11821 ttgtacacag gtacagctgg gttagatttt ataaagttcg ttgatacagc aattgcgttt
    11881 cctaaactaa gactcattat taatacctct ttctaaacat tatacatata ttatactata
    11941 gattctttat ctatgactta aagcttttta taattaatta agatattttt aaatctttgt
    12001 atctttttcc tagcgtacta gagcttatat cgtatttctt tgatatttga acttgagtta
    12061 taggttgtcc tgcttctttc ttaacataat attcaacagc agctgcccaa ccattttcag
    12121 ctccttttat attctcatga ttttttttat attcattcca aaactctata catgcatcta
    12181 tattttcttt ttcaacattt tctttaagag tatctaaaac tttacattcc tcttcagcta
    12241 attcattttc tgaattaact tttgtatcgt ttttatctct ctctttcttt aagtattcag
    12301 ctatacttgg gtctaaaagc tgttgtatat acttgtatag tatatgtgta tgataaatta
    12361 agaatgactt catatctttg tatacatctt gatattgatt gaatagattc ataatatcct
    12421 ttaaaattat atctttaacc tcatttgata tacttatagt tatatcaatc aatatgttag
    12481 ttccctcaat atcaactatt ctagctatca tacaacttcc gattttaaaa cttcttagaa
    12541 gttttacatc ttctgtacaa agttcatttc cacttaaaca gtcctttaat actatttttc
    12601 cagcagaaat ttcttttact tcataaatac ttacgtatga ttcaaacaga ctttttagta
    12661 ttgatacttc tgactgactt aagtttgcac cattttcttc aagaaagcca actgtcataa
    12721 cctttttatt ttccattatg tggtcttgta ttaagtaagt attaaaaaat ctttcaaatt
    12781 tttcatttac actatcattt tgcattatat aaaacatttc tttagctttt tcacattctt
    12841 ctttaaactt atcctgtctt gaataatcat ataactttga atataaatct gtatattgtt
    12901 tttgtgaaag ttcagttttt ctgcatgctc tttctgaaac aatatcttta tttaaacaac
    12961 atttcttgta ttttttgcca cttccacaag ggcatagctc atttctccct aacaatatga
    13021 cttccactcc cttattatta aattaaagta caatttgtta ttataccatt tttttattaa
    13081 tcaatctata gtataagtaa atattctatt aaattcactt atattttggt acaatatatt
    13141 aactttaatt aggatttcga taaaatcatc aacaatccct cttgtagaaa tgaattatcg
    13201 taaaactaat tcctctataa aattttatta attgataata gttttttact ttatctattc
    13261 ttttttgtta tgtgactcta actgtcattt tacattcaac aatattgtct ttttcttgtt
    13321 tatattcact gagaatattt tgagcatcaa aattatttac ttttaatttg ttaatttcta
    13381 tcttttcaag tttattattt agccttaatt tcttcattac atcttcaaat ttcaacacat
    13441 tttcaagttc tccattaacc tttatttcta aattaacttg ttttttgtta tgattatcta
    13501 aactactttc ttgattaata tattctatgt tcacaatatt tttcaattca ttttctacca
    13561 ataacactat atctttattt gtttttttat ctaaaaatga gttattaaaa ttatttttta
    13621 attcttcatt ttcatttaat tcaacacttt ctatatattt atcatctata tgcttattac
    13681 cctttatttg ataattatct tgattattta ttttatttat tatattttgc ttctcattct
    13741 tcaaactagt taagttttct tccaagtaat ttaccactat atcacttgcc accataataa
    13801 ctaatattaa tagtatttta agtagatttt tttctctatt atttaatctc aaaaataatc
    13861 acccatctaa ctttttattc taaatctata atattctcca tctcttacaa tactatctat
    13921 gtaataatat tttatgtact ttattttcct taaattgtct aaaacatcta aatcactaca
    13981 cacaccttct atctctaatt tatttttatc tatccatatt ctagtaatac tatttattcc
    14041 aattgtttca tatatttttt ttatttcatt aagttttatt ttagaaaatt tttctctagt
    14101 tttatctgtt gttgatatag tgtgctttga tttatcaact aacttatttt gacttatata
    14161 atcttcaagt tcatttatag atttcacata cataaatgat ttaaataaaa tacatgttaa
    14221 aattaagact attattattt tatagacttt attacatgat ttagtttttt tgaatccatt
    14281 aagaaaattt attgttttat ctactttcac ttaaataatc attcctatgc tacttatata
    14341 atttatacta ttgtcttcta aatctgtatc aaaattattt tctactttta ctttatcttt
    14401 taatcttaat ggatttactt caatagattt atctgtatat ttaaagtatt cttcaataaa
    14461 acaattttct ataccatagt aataaatata cttgaagtcc cttaataatc tttttataaa
    14521 ctcatatgat tttctctctt ttgatagcaa gtatgtttct tctatttttt tatcttttgt
    14581 tatatttata atcaactgac tttttttaca ttctataaat actccttctt ctgaaaagtt
    14641 ctctattaaa tttaagttta taagcttttg taatatatca aaatttatat ttatagtctt
    14701 tggattcata tttagatttt ctgaaatgtt cttaattaat tgaataatac tctttggaaa
    14761 aagaattact tgtatattca atttatcatt tatagaattt ataactttat attttattga
    14821 atagttactt atgtttattg gaatgtattg tgttatttca aattcaatca tgcttaatat
    14881 atctcttttt ttcttagtat ctagaacttc aacatttcta atgactatat cttgaatttg
    14941 aatgttaaag tataaatttt tatatgatat ttttgattta tcaatctcct cttttacaaa
    15001 tctaactaca tcttctatat atttaatctt ctcaatcgaa ttactatcat tttttatatt
    15061 aaagttaatc tcttttataa ttgatttatc tataaaaact tttttatgac tttttcttaa
    15121 aaatacaagc cttatataat catcatttat ttctaaattt agaatttttt taattgtagc
    15181 catctccttc ttaaataaaa ataaatttta aaacttacaa caatcaatat aaaatattat
    15241 tttggataaa attgcttaga atttatattc acgcttatat ctgttccgtt atcatttata
    15301 acaagttcga atttacctga tgtactctga ggaactggaa cagtatttag gtatcccttt
    15361 tccttcaatg cttctacact tagagagtct attatatttt catcatcatt aattgccata
    15421 ctagctgctg ttactatatt agcagcattc gtatagtctg catttaattt agcactttct
    15481 tgaaccttac tatacttaac taatgctata ctagatataa ctcctaaaat agttactact
    15541 acaatcattt caacaagtgt aaatcctttt cgttttttat ttatcaatta aatattctct
    15601 ccttttcaaa agtttcatct aataaaattt atttttcttt ctaaaaacta gtaattgcat
    15661 caaacatagg aacaaccatt gccaaaacaa aaatgccaat aattaatccc ataaagacaa
    15721 ttagcacagg ctctataaat ttcattattt gctctatttt gttatttaat tcattttcat
    15781 aaaatttatt tattacatct aggcttttat ctagtttgcc actttcttct cctgtatttg
    15841 tcattgaaat aaataatttc ggaaaaatat ttgctaaatt caaggattta cctatgctat
    15901 ttcctttttt tatatagtta ttagaaattt ttagcctttc ataaataaat tcattgtcta
    15961 taacactagc tgacatatct atagcttcca caatttgtat tccactacta attaaaatgg
    16021 acaacgccct tgaaaatctt gttgtagcta ctaattgatt aattcttttt acaaatggta
    16081 ctttaaattt taatgaatta gttaattttt ttatattatc atttgttata aagaaataaa
    16141 tacttcctat tgaaaacaat ataaaactaa atatcagata agctaaatta tttgtaacca
    16201 ctgtagatat tcccattaaa actctagtta ttaaaggtgg ttcaattcca ttactggtaa
    16261 aaaccacctg aaaattaggt attacaaata cgaatataaa caacattgat aagatagata
    16321 atattataag tattattgga taaattgaaa tagttattat ttttattttt aatttgtatt
    16381 ctttatcata ataattagat aaatcgctca ttattatatc taaattccca ctagtttctc
    16441 ctgcttttat catacttata aagaatttag aaaatatacc tgttatttga aatgattctg
    16501 ctattgagtt acctttttga atatgatttg atactatatt aagcaaattc tttacttttt
    16561 tacttgactg actctcaatg atttcaaata tctttgtaat ttcacatcca gattccatca
    16621 gtatgcctat ctctttgcaa attactctaa tttctttatc actgattcta tttaatacta
    16681 aataaaactt ttctaaatta caaaatatat ttttagataa tctcatatac tataatacct
    16741 tccaaattat attaattaca attaaataaa cttaatattt tctaatttaa tacatttaat
    16801 tttattttac ttgaatataa tttatactca aacatcttaa ttaaaataga ttaaataaat
    16861 acaattgagc aaacgaaatt taactattca attcagtcaa atcatttcat ttactactaa
    16921 acactcttct aatgttgtta ttttttcatt tattagcctt ttacaactat cttcaaatgt
    16981 tatcattcca ttattttgtg ccacgtcttt aatagtacta gaatcctcca tatttcttat
    17041 acatgtcttt atatcatcat taatttctaa aatttcataa attgctgttc ttccaaagta
    17101 tcctttatca ttacattttt cacaacctac agctacttta gtatttacat ctccactaaa
    17161 atcatctttt atcataatct catgactaca atgattacaa acttttctaa ccaacttttg
    17221 agatataaca cctataagag atgcgtttaa aagatatggt ggtatttgca tttctagtaa
    17281 tctagctatg gaagatactg catcattagt atgtaaagta cttataacta aatgacctgt
    17341 tatagctgct cttactgcta ttttagctgt ttctgcatct cttatttctc cgaccattat
    17401 tatatctggg tcttgtctta atatcgctct aagacctaca tcaaagctca accctacttt
    17461 tgaatttact tgaatctgac ttatgccatc catcttatac tctacaggat tttctatagt
    17521 cattatattc ttatttattc cttttaaatc atttaataag gaatatactg ttgtagtctt
    17581 tccacttcct gtaggacctg taaccaataa tattcctgct cttttattta ttatacgatt
    17641 tatagatttt atagcttcct ctgaaaaacc aagttctagc ttgtctttta aaaaagtatc
    17701 tctattaagt atcctcaaaa ctattttttc accataaaca gttggtattg atgaaactct
    17761 aatgtcaatt aaatttccac ccaactttat atctacccta ccatcctgag gaagcctttt
    17821 ttctgttata tccattgatg cctttaattt tacaaccgta gacaatgagg gatagacatc
    17881 aactaaaaac tttgatactt cctttagttc tccatctacc ctcattctca ctattaaatg
    17941 ttctttaaat ggttctatat gtatatcact tgcattttct tttatagctt tttctaaaag
    18001 attttcaaat aatttttttg catagtcctc gtcaagttca aagctattgt aatatttttc
    18061 aatcttttca cttataagtt ctttcttctc tttcttcaat ataatttctt tacctgtagc
    18121 taatctcaag tcttgtagag cataaatatc ctcatcttct atttctacaa ctaaattatc
    18181 atcttgaaat tcaactggaa atacattata tttttttgca agcttttctg gtattaacat
    18241 tggcaaactg ttttcctcta atataatctt aatcaccctt tatatacttt aatttattag
    18301 gtatattcat ttttttcata gagatatttt cttcagtttt tatgcttatt ttcattggat
    18361 aattggtttg tatgctatct aaatatttac tacctttatc tacataatta gatagtttct
    18421 ccttatctcc aatgcacttt atttcatatg gctgtgctac aggaactcca tttatattta
    18481 tatggcttcc tgcaaggaca acttctgaat attgattaat tctttgacca tttatttcta
    18541 tgtattttcc tccatttaat tttaactcat ttatgacttt tacaagaatc ttattatagt
    18601 ctatactatt agctatatta cctgtttttt catctatagc atctatactt aatattatcc
    18661 cactaccctt catatctgaa tatgatagac tatctctaag cgtttctatt tgtgatattt
    18721 tttcagaatt tttttgattt tttttcattg aatcaatttc tttatctaac ttgcctttct
    18781 ctttggttaa ttcttttata gattttcttg tcatttttat ttcttttctt attgacttat
    18841 ctttgcttgt ataaactgtt tcttcattgc tataatctct aaatatggtt ccaacaagta
    18901 tacctaaaat agtacttgct agtattataa acacatattg ttttttcata ctgtattgct
    18961 ccttacaaat ttatttttat gtgataattt tctttaatta aatattaaac atttacatac
    19021 gtttattata tcaaagttat atattaaaat tcacctttag tatataatat catatattga
    19081 actcctatca ctaacttacc aatatcaagt atgtattttt aaatgttatt aaaattatat
    19141 aaactttcaa taaacattgt tgtaatatta taaaaaacat aaattagaaa aggagataat
    19201 aatcatgaaa aaacaaacaa taaccttagg attaacaagt ataatagatt tatgaggaat
    19261 tggtttactt aggcaaatca tttgcagata aaaatactgt taaaaaaaat ttcaactaac
    19321 tattctggat atgacatact agaaaaatga aattcaacta tttctactgg ttttagttca
    19381 aagtaaattc atcatacgct tatattttca atcaaattat ctttttttat ataacaattt
    19441 atgattatta ataattattt tctatcaaaa aagtaaaatg gcatagcctt aaagctacac
    19501 caatttacta aaaattatat cataattaac attaatgtta aacatatgcg tttataagtt
    19561 ttcctcatat tttaaaattc ttttaaccaa gttatctctt aattttccta cttcatcaaa
    19621 tctcatatta ggactatagt aactttctat aatatcatgt ttagatttag ctctcttaag
    19681 atttaacact gcccaacaaa ttaaatcatc taaaactttt tcatcaaatt taatatcttc
    19741 ttcatattta agtagttttt ctctatttaa aaactgattt aaatcaatcg tatcttcttc
    19801 tttaaaattc gtgcttatag ttatacctat atctaagtca gttaatagta tagtttcaat
    19861 tttctctgga ataagtggat aatggtaaac ttctacattt aaaccttttt caatagcttt
    19921 attatacact ttgtttaata gtgtagtttt cccagttcct atttctccag ctaaataata
    19981 aaccttattt acatctttta aaatgttttc tgtataatct aaacacccta caggagttat
    20041 agctgaacca aataaatgct tttctctttt tagatttcct gtgcttttaa ctccatcaaa
    20101 taaccttttt ataaattctt ctgtgactaa atttacttta ccataatcca tacaatcaga
    20161 atatttttct tctatgtctc taaagattgg ttctgccgat tttaaaaact taaatgctct
    20221 cttaaatgaa ttactaatat ctttatcgta gactgatatt tcttgtctat tcttttctaa
    20281 ttcttctgta ttccaataat cacctagatt aattatctcg tccaaagctc caggtagctt
    20341 tgggtccata gtatgtggag cagttgcatc cataagtacc actcctaatt tctttataac
    20401 taagccatcc aacgaacttg ggtcagaagg acaatgatat aaatcaatat catatcctcg
    20461 atgcaaaaac tctttataaa tttttttcat aagtgaggat tttcctactc caggtccacc
    20521 ctttaaacaa aaaactcttt ttacattttc aggaattata tagtcaaaaa aagaatatga
    20581 gccttgtgat gtatttccac ctgggaatgc cttctttacc tttccttcca tattagcgcc
    20641 tcctcataat ttacaatatc tcttaattaa gatattcata ttataagaat tttattacag
    20701 ctttctgatt ttgacaaatt taaaacttgc tatctaatac taataacagg ttcattttat
    20761 ctaattattg tagattctta tgctatgcct ttttatctat aaatgcaatt taagtgtcca
    20821 tatctaagta tttgtattgt aatatagctc tatattactt aaatccaatt gtttccatta
    20881 taattttatg ttaaaataat attacaaaat acatctgttt ttcttcataa acgggtgaaa
    20941 ttccctatcg gcggtaaaag cccgcgagcc ttatggcata atttggtcaa attccaaagc
    21001 cgacagtaaa atctggatgg tagaagaaaa tagtatatga gtacctttat gtaattttac
    21061 atgagtaatc tatacaaatc cttcaactac cgtatttatt catgaaatta gacacattca
    21121 aggtacctaa tatacaggtg ctttttttgt tgtttatttt ataattatat cgtacttata
    21181 aaatctatta agattggagt gttatcatga aacaaaaatg gatagtattg attatcatct
    21241 gtattggtgt atttatgtct actcttgatg gaagtatact aaatatagca aatcctacaa
    21301 ttgctgctga ctttaaaatt aacatgtcac aaattcagtg ggttgtaaca gcttatatgc
    21361 ttgttgtaac agctactatg ttatttttcg gaaaacttgg cgataaagta ggctcaaatc
    21421 gtctatacac attaggattt tttatattta caataggttc ttttctgtgt agtatgtcaa
    21481 acaatttatc aacattaatt tcttcaagaa tttttcaggc agttggagca agtattttaa
    21541 tggctaccgg acttggtata gtttccaatg catttccaac aaacgaaaaa ggaaaagcta
    21601 tcggaatcac tggagctgta gttggtatag gaaatatgag tggacctgta attggaggta
    21661 taattttaga acattttgga tggccttcta tttttattat caatatacca attggtatta
    21721 tagcagtctt tcttggtatt aaatttcttc ctaagcctgt tttagatgag caaagcaaaa
    21781 gctttgatat tccaggtctt ctacttttcg catcttgcac tacgcttata ttacttgcaa
    21841 tgaatgagaa aggtaataca agattgtatt taggtataat agcacttata atcttcttgc
    21901 tattggcatt gagagaagta aaatttgaac aaagttttat tgacctacct ctatttaaaa
    21961 atagaaactt tactgtaggc aatatcattg gagtagcttg ttattttcct caaatggcag
    22021 tatcttttct acttccattt tatttagaac aattaaaaaa tttatctcct atgatggctg
    22081 gttctgtaat gactgtacat ccacttatta tggtacttat agcacctatt gcaggttctc
    22141 tttctgataa acatggtgca aaaaatattc taacagcatc tttttcattt atgaccatct
    22201 cactagttgg aatggcactt ttaaaagcag attctccact gtatctttta attgtatgtt
    22261 tagttatttt tggacttggg ctaggagcgt ttagttcacc aaacaatagt agtattttag
    22321 cagatgttcc tcctcaaaaa cagggatatg gaggcagttt tcttgcaact gttcgtaatt
    22381 tgtcatttgc tcttggaaca gcatttttta gcagtttttt tgcacaaagt cttacataca
    22441 atcaaaagtt caaaagtcac acatcagcct atgttatagc tagcaataaa tcttattgga
    22501 ttgcagcatc agtatgtttt atagggctta tactaactgt tttctttatg agaaaaacag
    22561 ataaatctat ttcttaaata aaatttattt ctgatttcat cagtgattaa attcttaaat
    22621 atactaattt atatcaaact ttacagtttt tttctaattt ataacaataa attgctaata
    22681 tttattgttt ataaacaaca aggatgccaa aaaatgtcca ttaaaactat tttgaggcat
    22741 cctatatttt attttgatat taaaacagtt agaactaatc taatgttatt ttatatagat
    22801 tatttaaaca agtattacgc caacatttga tagtttaaat ttaatccact gttatctcat
    22861 atccatgttg attatattga tttacaattt cttcccatag ttcttcaaca ccagtctttt
    22921 ttagtgaaga aacaggaatt actttttcgc tactttccat ttgcaatttt tttcttatta
    22981 tacttatatg tttttgatat tgacctctag atattttatc tgccttagtt gcaataacta
    23041 cacagttata tccaaagtgc tttatccatt catacataag cttatcatct gctgtaggtt
    23101 catgtctaat atctacaagt aggaatatag aacataactc ttgtctactt tctagatatc
    23161 tttccattat acctccccac ttttcttttt cagacttagc tatctttgca tatccatagc
    23221 ctggaaggtc tacaaaataa aattcattat ttattaaata aaaatttata gttctagttt
    23281 ttcctggtgt ttgactagtt ctagcaaaat ttcttctgtt aagcaatgta tttattattg
    23341 atgattttcc aacatttgac ctaccagcca atgctatctc tgggattcct tctgctggat
    23401 actgtgattt attcacagca ctcatggtta tctctgaact tctaattttc attattttca
    23461 ccactcttta ataaagcttg ttctaatact tcatccatat gctctacaag cacaaactcc
    23521 attttttctt ttacattttc tggtatttca tctaagtcag cttcacactc tttaggaatt
    23581 aatacttttg ttataccagc tctatgagct gctaataact tttctttaac tcctcctact
    23641 gctaatactc tacctcttaa agttatctct cctgtcattg ctatatttcc aggcacaggt
    23701 cttttagtaa gtgctgagat tactgcaaga gccatagtta taccagctga tggtccatct
    23761 tttggaacag caccctctgg aatgtgtata tgaatatcat tcgtcttata aaaatcaggg
    23821 tctatatcaa acttgtccac tattgacctt atataagaga tacctgtctt agcagattcc
    23881 ttcataacat ctcctagctt tccagttaat acaatttctc ccttaccttt aagtacattt
    23941 acttctactt caagtgtaac tccaccaact gctgtccatg caagaccatt tactaatcct
    24001 atttgagggt taacttctgc aagttgatac ttaaacatat cttttccaag atatgcctct
    24061 aagtcagact tacttataac aacttcttca agagttgggt cttcaacgta ttttttggca
    24121 acttttctac aaatcttacc aatagttctt tctagtgttc ttacaccagc ctcccttgta
    24181 taatgattaa ttatacttct taaagtttca tcatctattt ttataaagtt ttcttttaaa
    24241 gcatgttctt taatttgttt tggaagtagg tatttttttg ctatatttaa tttttcttct
    24301 tctatatatc cagatacttc gattacttcc attctatcta ataatggtct tggtatatta
    24361 cctaggctat ttgctgttgt aacaaatagt atttttgata aatcaaaagg tatttctaag
    24421 taatggtcca caaaatcctt gttttgctct gggtctaata cttctagcat tgctgaagct
    24481 gggtcacctt tataatctgc tgccatctta tctatctcat caaataagaa cacaggattt
    24541 tttgtttgag cttcttttac cccattaatt attcttcctg gaattgaacc tacataagtt
    24601 cttctatgac ctcttatttc tgcttcatct ctaactccac ctaaagatat tcttacaaat
    24661 ttcctattta atgctctggc aattgatttt actatagatg tttttcctgt tcctggagga
    24721 ccaactaaac atattatagg acctttaagt gacttagcaa gagttcttat agctagatac
    24781 tctagtattc tctccttaac tttttctaat ccataatgat cttcatctaa tatatctttt
    24841 gccttagtta tatctaattt atcttttgtc tctttattcc atggtaatga gaatatagta
    24901 tctaaatagt ttctgcttac agatacatct ggagacattg aagatatttt tgaaaattta
    24961 tctatttctt tttctatttt ttctttagtt gtcttaggtg cttttatttt tttaagcttt
    25021 tctctatact catctgcttc agagtttata tcttcttctt cacctaattc tttctgtata
    25081 gcttttaatt gttctctaag ataatattct ttttgaactt tattcatctg tttttttact
    25141 cttaaagtta ttttcttttc tatttttaat atatctattt cctctaataa tatagaataa
    25201 ataagttcaa gtctttttct aatatcaaat tcttctaata tttcttgttt ttggcttgat
    25261 tttagatata tgtttgcagc tatcgtatct ataaatctat ctacatcttc tatatcagct
    25321 aaagatatta atatttctgg tgatacccta ttcccaatat ttatatactc ttcaaaggca
    25381 tcaaatacat ttcttacaaa tgcttcaatt tcaacttctg tctcactatc caaattatca
    25441 ctatcaaaca ctatttcttc tattactgct ctgaaatatc catcttcttg ttctattttc
    25501 tttaccttac ctcttgatac accttcaact aaaacacgaa ctgtatctcc tggtaatttt
    25561 atcatttgct taactttaca gattgttccc acatgataaa aatcctcttc tcctggctca
    25621 tctacctctg cttctttctg agaagttaaa aatataagtt cttcatccat catagcttgg
    25681 tctaaagctt taagggatat ctctctacct atatcaaaat ttaatatcat atatggaaat
    25741 atagctaatc ctcttagagg aattaatggt aattcatgat ctattttagt ataattttgt
    25801 tccatcaaca ttactccttt tctagtctaa ttgctttgct tttaatatta tatatttgaa
    25861 caagttaatt ttcaacatta atgataaatt cttagaatac tatcatacta tattatcttt
    25921 ttattatgat ataatattaa tattagtata cttagatgtt atttatcttt tggaggtttc
    25981 tattatgttg aaattgtttt taaccttttt aaaaattggt gcgtttacat ttggtggtgg
    26041 atacgctatg gttcctctta tacaagatga acttgtaaac aaacaaaaac ttttagagca
    26101 ggaagaattt attgattatt tatccatagc tcaaagttat cctggagtac tggcagttaa
    26161 tatatctgta ttattaggat ataaacttta tggtatacca ggagttctta tatgtacctt
    26221 aggctctgct ttaccatcat tttgtatagt cttagtctta tcgtatctat actttaaaaa
    26281 ttcatcatct aaaattttag atggattttt taaaggagtt gcgcctgttg taatagctct
    26341 tatattgtat tcttttacga gcatgttcaa gaaactacca aagtctaaaa ctaacatact
    26401 actattaatt atagcagttt tatctgttgg tgtattcaat ataagcccta tttatttaat
    26461 aattggagga ggtgtatata gtctatgtca gaaataatac tactcttctt aatattcctt
    26521 aaaatagggg catttagttt tggtggcggt tatgccatgc taccatttat ccagcaagaa
    26581 tttatatcta aatatcactt tataactaat caagagtttt tggatttact tgctatatca
    26641 caatctacac caggtcctgt agcaataaat agtgccacat ttgtaggatt taagactgct
    26701 ggcttctttg gttctctagc tgcaactgtt ggtgttacaa tttttgcatt aataggtcta
    26761 actattatat caaagttatt ttctaagttt aaaaacaata aaaaagtaga aaacttattg
    26821 acagttctta gaccaattac tctaggattc atattatcag cagctttttc atctgccaaa
    26881 gaagttaact gggatttata tggaataatt gcatttatag catcatttta tcttttatat
    26941 aaaggaaaaa ttggttccat tgcaattgta ttcgtctttg gtattctagg tatattactc
    27001 acatttttat aataatgata cctattatat ttagcatatt agcataaaaa aaggagcttt
    27061 taaagctcct tttcatcatc ttatgcactt tcctcttgat ccttaagtac tatgatagga
    27121 tttactgagt cttcgttcac agatttctct gttactataa ccttctttat attatctcta
    27181 gatggtactt caaacatagt ttccatcatt acactttcaa ctatacttct aagtcctcta
    27241 gctcctgtat ttctttctat ggctttttta gcgattgcac gaagagcacc ttcttcaaat
    27301 tctagctcaa catcatctaa ctccaataac tttttatact gttttactag agcattttta
    27361 ggttcctgta atatctgcat taatgcatct tcatccaaca actctaaagt agctaaaact
    27421 ggtattcttc ctataaactc tggtattata ccatatttta ataaatcctc tggaagtact
    27481 ttttcataca acttccctaa atctaattct tttttacttt ctattttagc tccaaaacct
    27541 agtgttttat ctccaccacg tttttgaatt atcttctcta atccatcaaa agctccacct
    27601 aatataaata atacattagt agtatctatc tttaaaaatt cttgatgagg atgttttctt
    27661 cctccttgtg gtggaacatt tgcaacagta ccttccaata tttttaaaag tgcctgttga
    27721 acaccttcac cactaacatc tctagttata gatgggtttt cagattttct tgcaatctta
    27781 tctatctcat ctatatatat tatacctctt tcagcttttt ctatatcaaa atcagcagct
    27841 tgaataagtt ttaaaagtat attttcaacg tcttctccaa catatccagc ttcagtcaat
    27901 gatgtagcat ctgccattgc aaaaggtaca tttagagttc ttgctaaagt ttgagcaagc
    27961 aatgtcttcc cagaacctgt aggtcctaat aaaagtatat tactcttttg aatttctata
    28021 tctttgctac tagatttttt actatatatt ctcttgtaat gattataaac tgcaactgat
    28081 aaagcttttt tagctttttc ttgacctatt acataatcat ttagaatctc catcatttcc
    28141 tttggttttg gtaaagatgt agtatcctca tctatagtat cttctatctc ttcttgaata
    28201 atttcgtcac aaagttcaac acactcgtca caaatatata catttggacc tgcaattaat
    28261 cttcttactt gatcttgatt tttaccgcag aatgaacact ttaattgtcg tttttcttca
    28321 tatttagaca tattaacacc tctctctatc tacggtctct ttgtaaatac ttcatctatt
    28381 aaaccatatt ctttggcttc tagtgcactc atgaagttat cacgttcagt atccatttta
    28441 attttttcta atggctgacc agttctttca gataatatct catttaaagt ttcttttatt
    28501 tttaaaattc tctttgcatg aatttctata tctgttgctt gaccttgagc tccacctaat
    28561 ggttgatgta tcattatttc actatttggt agtgctagtc tttttccttt tgctcctgct
    28621 gccaacaaga atgctcccat agaagcagcc atacctatac atatagtact tacatctggt
    28681 ttgatgtatt gcatagtatc atatatagcc attccagaag ttatacttcc tcctggagaa
    28741 tttatatata aatgtatatc tttgtctggg tcttcagctt ctaaaaataa tagctgtgct
    28801 actataagcc ctgctgtggc atcgttaact tgatctccta agaagattat tctgtctttt
    28861 aatagtctag aaaaaatatc ataagatctt tctcctcttc ctgtttgttc aacaactaca
    28921 ggtactaatg ccatggtttc ataccccctt tattctatat aatttacagt agcttttttt
    28981 aagctactgt aaattattat acgcatttaa ctaaattata tttgcacatc attatatact
    29041 aaacatttca taacgtcaac tatattagtt agcgtttatt ttattaagct attgttgcat
    29101 tatcaactag taaatctatt gtttttctta tttttatttg accttttata tcttctttgt
    29161 cagcatctct taaagaagct tctatttttt ctacttccat attgtaagca gaagccattt
    29221 tttctaactc agccttaaat tcttcttctg ttgcttcaat tccttcagct ttagttattg
    29281 cttctaatac taaagaagat ttaactaatt ttttagcatc ttcttttctc tcttctctta
    29341 attcttccat agttctacca gtcatctcta ataattgttg taatccaaat ccttgatatt
    29401 gtaattggta gttaagttca tttaacatat tatctatttg atgttgtatc ataacttctg
    29461 gtatttctat ttctgtattt tcagcaactt tttctactac tgaatttcta gtttctgcat
    29521 ctgctctatt tttagcttct tcttctaact tagctcttac atctgctttt aattcatcta
    29581 aagaatcaaa ttcactagta tctttagcaa attcatcatc aagtgcagat aattctttta
    29641 cttttacatc gtttattttt acattaaata caactggttt tccagctaaa tcttgtgagt
    29701 gatattcttc tgggaaagta acattaactt ctacttcttc accagctttt ttacctacta
    29761 attgctcttc aaatcctggt ataaatgtgt ttgaacctat aactaagtta taattttcac
    29821 ctttaccacc atcaaaagct acaccatttt caaaaccttc gaagtctatt atagctgtat
    29881 ctccatcttc taaagcttta tcttctacac ttactaatct agcatttttt tcaaccattt
    29941 cttgtagttt agcatcaaca ttttcgtcac ttacagtatt ctcaacctta gctatttcta
    30001 tacccttgta gtttcctaat tcaaactctg gtttaacttc tacattaaga accataacca
    30061 acccattgtc tttacttatt tcctctatat ctaaatctgg attgtctatt gggtctatgt
    30121 ctaattcctt gatagcttct ggataaactt ctgggaataa tatttctata gcatcattat
    30181 agaatatacc ttttccatat tgagtttcta taacaattct tggagcttta ccttttctaa
    30241 atccaggtat attgtattta tttctgcttt tattataagc cttatttact gctgcttcaa
    30301 atttattgtt atctactgtt atttttaaag taactttatt accctctttt ttaattagtt
    30361 ctgctttcat ccttctaatc ctcctagtga tatttatgta atacccgata acggtattat
    30421 aattcattct atttataatt caaccactta attatatcac ataagttttt ttatttacaa
    30481 gtgttccatt aatatcgttg tacttatttg ataaaattta attttttgag cgttttttgc
    30541 cattttttta gataaataca cctttatatg cgtatttctt ctatatttat gttatcttct
    30601 tctatatcca taatgacaaa acttttatac gatactcctc ttggaagtga agtacttcca
    30661 ggatttatgt aaagtacacc atctttaatt tctctaaacg gagtatgggt atgaccaaat
    30721 ataactatat cagcatcaat ttcagttgcc tttttttcta acatatgcgt tccatatttt
    30781 acaccatact tatctccatg acataagaat atagttttat ttgccacttc aaagacaact
    30841 tcttcctcaa cagcatcaaa gtcacaatta cctttaactg caataatacc tacattagtc
    30901 atgctatgaa tatatcttga atctgtaaag ttatctcctg catgaattat taggtcacat
    30961 tcttttaaat atggtattgt tttttccata tttttaatca tcatatgtgt atcgcttact
    31021 atgcctattt tcattacttc actacccttt ttataaactc ttgtttcata agttttagtg
    31081 catttgctct atgactgatt gaatttttta taacactagg tatttcacca aaagtcttat
    31141 catatccttt tactataaat aaactatcat atccaaaacc atttttacct ttttcttcaa
    31201 atcctatcat tccttcacaa attcctctta ctacaaattc ttttccatca ggaaaaacta
    31261 cggctattgc agagacgaat cttgcatttc ttttactcat tggtacattt tgcatagctt
    31321 ttaacagttt ttttctattt tcttcatccg ttgcatgttc tcctgcatat ctagctgaat
    31381 aaacaccagg ttttttgcct aaagcatcta cttctaagcc agaatcatct gatattgcta
    31441 taagtttagt cttttttgct attgttctag cttttatcaa cgcattatgc tcaaatgttt
    31501 ttccatcttc tactatatct atacctgcta aatcaacatc ttttaaagag tatactttat
    31561 actcaaaatc ttttaagatt tcacctattt cttctagctt atgagcatta ttagtagcaa
    31621 tcactacttc attaccataa tccataccca atatttcatc tgctatttca cctaaagctt
    31681 ctttttgaag ccttattaat tctttattcc ctttttcacc taactctaac aataaattta
    31741 aatctgttct cgaaaaaggt ttctcttctc cagtcccctg tacttctaca aactcacact
    31801 tatcagtcat tattatattc atatctacct gtgctttaga gtcttcttca tagcataaat
    31861 ctagcatgtg tgttccattt acaataccaa cactaattgc agatacaaaa tttgttattg
    31921 gcatttcttt tactgtcttt gctttatata atttatatat tgcttctgca actgctacaa
    31981 atgcccctgt tatagatgca gttctagttc caccatctgc ttgaattaca tcacaatcta
    32041 cccaaatagt tctttcccct aatttattca agtctacaac agaccttatt gctcttccta
    32101 ttaatctttg tatttcttgt gttcttccat caatttttcc cctagatgca tctcttatct
    32161 ttctttgttg tgttgctctt ggtagcatag aatattcagc atttatccat ccagtgccac
    32221 tatttcttaa aaaaggagga actttttctt ccactgatgc agtgcatata acctttgtct
    32281 ctcccatttc tataagaaca gaaccttctg catactttgt ataatctcta gttatcttta
    32341 caggtcttat ctgctcgtta cttctatcat aacttctggt cattttttat atcctttctt
    32401 atatttttgt tttttataaa tttattttta taatttttaa ttttgtcaaa tattaattat
    32461 tgtcattttt cgtaatctta ttagcttact gaactattct atcattaatt atagtagttt
    32521 tctactaaat taagcgactt tttaactctc taatatagct tttacttcat ctttcgatga
    32581 taactttaat agttctaaaa atctctcttc atctataact ttaattccta aatcatttgc
    32641 tttagcgagt ttagaaccag cttcttcacc tgccaaaaca aatgttgtcg atttactaac
    32701 actagatgta gcttttccac ctcttttttc tatcatatct tttgcatcat ttctttttaa
    32761 tgtaggaagt gtaccagtca atacgatttt catcccttca aatatttttt ctactttttc
    32821 acctgtatta tccaatgatt ttgtatttac tcctacattt tttaacttgt ttataacgtt
    32881 catatttttg tcttccttaa aaaactcgac aacgctgttt gccattatac ttccaaattc
    32941 ctctaattct tctagttgtt cactcgttgc agacatcaca tcatctaaat ccttaaagtt
    33001 atatgcaagt atcttagctg ctttaactcc tataaattta atacctagtc catttataag
    33061 tctccataaa tcattttctt ttgatttttc aattgaattt attaaattgt cagcagattt
    33121 ttcgcccatt ctctctagct cgactacatc ttcctttttt atataatata aatcagatac
    33181 atcttgaata attttttcat ttaatagcag tgtaattata gattctccca atccatctat
    33241 attcattgca tcccttgata caaagtgtat aattcccctt cttatttgag ctggacaaga
    33301 catgtttata cattttacag cagcttctcc ttctaatctt attgttggct ctgaacaaac
    33361 tggacacttt tctggcattt taaaatctat ttcatctcca gtacgttctt cttttataac
    33421 ttctaaaact tgaggtatta tatcccctgc tttttgaact aatactgtat catttatttt
    33481 tatatccttt tctcttatat aatcttcatt atgaagtgta gccctgctta cagtagtacc
    33541 tgcaagtctg actggttcaa gaattgctga aggtgttatt gtaccagttc tcccaacttc
    33601 tactattata tctactattt tagttttctt cttttctgct gggaatttat atgcaattgc
    33661 ccatctagga cttttggctg tatatcccat ttcgtctctt tgttttatat tgtttacttt
    33721 tattaccata ccatctattt cgtattctaa attacccctg ttatctgtcc aatattcaat
    33781 gtgttcaata acttcatcta tacttttaca aactttataa ctctgactta ctgaaaatcc
    33841 tagtttttct aagtactcta gcgagtcact gtgactttct aaatcgtaat cttctatatt
    33901 ttccatatta aatacaaata tatctaatgg tctctttgca gttagttttg ggtctaattg
    33961 tctcaatgaa ccagctgcaa gattccttgg attggcaaat aatggctgtt cttgttcttc
    34021 ttgttgttca tttacctttc taaaattatc ttttgatata tatacttctc ctctaactat
    34081 taactctttt ttatcattta tcttaagagg tatgcttttt actgtcatta ggttttgaga
    34141 aatatcttct cctacaactc catctcctct agttgctcct ttttcaaact ctccattatt
    34201 ataagttaga cctacagaaa gaccatctat tttaaattca acaacatatt caacattttc
    34261 tccaacatat tcttgaaccc tcttatcaaa atccctcaaa tcttgctctg aaaaagcatt
    34321 tgataaactc aacataggag ttttatgtac aatttgattg aatttatcta atggcttacc
    34381 tcctacccta tttgttggcg aatcaattct cttcaattct ggatgttctt cttctaaaga
    34441 aattaactcc ttcattaact tatcatattc ataatctgat atttctgggc tatcttgatt
    34501 ataatacctt tcattatggt aatttattgt ctctataagt ttattaattt catcttttat
    34561 gctcactttt tgcacctctt catatttttt aaattaaatt attttgaaat ttccttataa
    34621 ttaattatct cctatttata tattttttag tatatcactt ttttgacttt aaatttatta
    34681 caaaaaaaac tcttattagt atatctaata cgactaataa gagtttttta tttttatcaa
    34741 aattttttat ttttagtatc ctcttgatat gtctacaacg ttatctacag gtttattttc
    34801 cagtatatag tgtttcaagt tattataaac catattaaat gttctctctt tgtttttatc
    34861 tgacacccaa gaattatgag gagttactat gacattttca cactcccata acttattatc
    34921 cttgtttaaa ggttcacttt caaatacgtc taatgctacc cctctaaatt tttctataca
    34981 ttcttctaaa tctttctgat taactgtatt tcccctacct acattgataa atacagaacc
    35041 atctttcata agtttaaaca tatctttatt tactattcca tctgtgcttt ttgtagaagg
    35101 cattgctaca actactatat cacattcttc aaatacaata ttcatatcct cagtggcaaa
    35161 acacttatca aagtattttt tactacttcc cgcagtattt acaccccata tttctagacc
    35221 aaaagctttt aatctttttg ctgcttctga agatatagta cctgttccta aaaatccaac
    35281 tctttgtcca tacaattccg atacagaaaa atccatcttc cattctttat tttgttgttg
    35341 tttaaaaaat tttgcactat ttttatatat ttctaaaata tacaatacaa tgctttcacc
    35401 aataggtaca ctatatccgc ctctattatt agctatctta atatttctct tcaatacttc
    35461 ttcttttgga agttggtcta tacctacact tgttgtctgt atatattgta aatttttcat
    35521 cttagagata tctaatctct caaatggatt gtatgtaact agtacatctg ctgtatttac
    35581 atcctcatta ttttcaataa tatcttcaga ataatgtatg acatcatagc ctaaatctct
    35641 tattttatca aatttttctt ttccataatt tattgtaaat aaaactttca tctcaaatct
    35701 cctccatcta ctcacattaa aaattttata ttctaaagta taatatgata ctcaatgcac
    35761 attagttaaa attactagaa gatatcttaa atttacttat gttcaattgt ttttcctaaa
    35821 gacatagcat tacgttcttg aactaaattt tctattaaat tattcaatgt ccaatcaata
    35881 gatgtctctg ttaccatagc tgtaaaaggt ctatttatcc tcactttttt tagtccttct
    35941 aaaaatgcat ttacctgtgt acttggagcg ttattaaata ttacagactt actcttaatc
    36001 ccattttcac attcacttga tatatttcca tctaaaatgt ctcttattat attatctcca
    36061 tttttatcac ttaagatgat atggtctctt attccagcaa agttacttac atttttaatt
    36121 aatgataatt cttttttatt aaaatttaca agcataatac acttcctatt gtgtatttta
    36181 tctaggttat tattatttat tttttcaaat gacattttat ccatcctttc atttatttat
    36241 atattttaat ttaccccata catttaaaat aatcaatttt tatagttaat ttttatatta
    36301 atacccaaat tatatttaaa tagttagact atccaaaact aatatataaa attagaataa
    36361 ttagattaat atctacaaat cataacctaa aggagagata ccatgaatac attactaaac
    36421 aataaattta gcattaaaaa tttttcaaat gcttgggtta tagtgcttgg ttgtatgttg
    36481 atacaagctg ttccatttag tattgtagca agtatacaac ctcaatttat aagttatgtt
    36541 gtagaaggag aaggctttag tttagcttct ttttctctaa tattcactat tggtactatt
    36601 gcctcagcaa ttgcatcacc ttttataggt gtattatttt ctaaagtcaa tattaagata
    36661 ctatatttat taggttgtat aatttctagt attgcttttg ctactttttc tatatgtact
    36721 gaactatggc aattttacac ggtatcatgt attgttcaaa ttggtgctac aattatatct
    36781 gctataggaa tacctgtttt aataagtgct tggtttgatg aagaaagcaa aggaaaagct
    36841 ctaggctttg cttttgctgg tggttctatt ggtagtatat ttctacaacc acttgcagtt
    36901 cgcttactat caactcaagg atatagtcgt tcttatctaa tatttggaat tgtagcatta
    36961 atagttggta tacctgtaat gtatatcagg tgacaccgta tgatatgatt ggaacgccat
    37021 tctaatgcgg tatctacggg atttgttgaa aagtcaaagt atcgtaaaat gatgtcaaat
    37081 attgggctgt atcgcaaaat tgggagtaca aagggagtac agaaaaaatc ctatgggagt
    37141 acaaaaagta tgatataaac tgtcttttgg aacaatatta tgagggcgta ttgtgtaagc
    37201 gatatgctct ttaatttttg agaaaagtaa tgctacagac taggaaatat gatagaatga
    37261 cagaaataaa taggaattgc agtattgaga atgaggaggt ttagtttatg caatatttat
    37321 tgataattat cataggactt ttgcttttta ttgaagttga taagttgaaa aaacaggtaa
    37381 aatcacaaca aaagcagatt gatactttgt gtgaacagac ggggaataat caactggcaa
    37441 cgtatcatat atcggatgag gataaagaac ttattcttca tttgaaaaat agtggaaaag
    37501 atgtagaggc tgtgaaaaaa gtaagagaga ttactgctat ggaattagaa gaagcaaaac
    37561 aatatgtaga ctctctttaa gagttcaatt ttctgatata gtaaaaagta agatttggat
    37621 aatggaggtg ttcaaatgga taaaagacat tggttcttac ttggttattt aattattcca
    37681 gtatgctttt ttgttgcagt tattgtagtt ggtttgctaa gaagtcattc tttaattgaa
    37741 atttataatg acggattagg aattacggca ttatattacc ttttacttag tctgtttgta
    37801 tatattcgct ggcaatattt ttctgacaaa taaagaattt aggaggttaa gaaatgtata
    37861 ttatttatac agtgttagcc gctatagtgg gtatggcttt ggtagttacc gttgatatgg
    37921 gaataacaaa gatatttgat aaaaagagca tttttcaaaa aaattatatt aagatgccac
    37981 tttcttattt cattgggatt tttgtttttc ttttgattgt gagattgatt ttttcataaa
    38041 gaaatagagt tgtaaattca gctttgtagc agacagtttt aatgtaactg tctgcttttc
    38101 ctttttaatc ataattgata atagtgctat aaaatggttc atatccattg tgaaaagacc
    38161 atttagagtg atatagattg attataagag tagtaggagt cccgttgatt tgattatgtt
    38221 ctgcttcgat ttccgctacc acttcatcgg tattccagta ttgatatacg ataacttgca
    38281 attcggtatc acgattagcc ccattgctga atgacatact gttaaataca agataatcgg
    38341 gcaagctaat gtaatagaga atgcctgcaa gcaagactag aataatagtg gcaaataaca
    38401 atttcttttt cattttgaca tacctcagtt tctatatagt tatagggata actatatagt
    38461 acctcgctat atagtgaatt gctacataaa gatttattga atatactttt atgtagaggt
    38521 gaggcaatga agtatggaca tttggaactt cacatagagg aactgctgaa agaaaaagga
    38581 attagtaaga ataccatttg taaggaattg gatataccga ggtctaactt taatcgttat
    38641 tgcagaaatg aatttcagag attagacgca caactaatct gtaaactgtg cagttacttg
    38701 gattgtggaa tagaagaatt gatagagtat gtgaaagaat gagagcctgt cggattgaag
    38761 aaaattcgtg caggcttttg ttgtgtcaag aaaaagagaa aacgtagtta ggtcaaggaa
    38821 caaggcgaag ccgatacgcc gtagggcagt ccttgacgga acggacatag ccaacagcac
    38881 catgatacag tagaggactt gaaaggtcag aaaccttgca agtcctcttg tctgttactg
    38941 gtcgttatgt tttaagtaaa gtgcttcttt catcagttct ttttcaaatg ccttgatgtg
    39001 accgccctgt attccgttgt tgatatgaaa gcaatcgtca gcctgtgagt aggatagcat
    39061 ggtaactttc ggctcatagg tcttggtatc aattccataa tagtaaatcg tggcggttgt
    39121 taataccatg tgaatgcttt caaaatctct tgtaaaaatt gtatgcctgt cggaatagaa
    39181 gaaatcagac ggacattcat agaattggga actatcctct ttcaaaaata gtggcagtat
    39241 gtgcattgca tttccagcac gattgacaag gacataaaag cgtggaatga gggcggcata
    39301 ttgtgtcatc atggcgatat atatatcatc taaatcatca agaagatact cagagcagga
    39361 gttgttataa aagacatatt gcagggcgtt atcgttttga cttgtatgtt ccataggcac
    39421 attttgtccg taaagccaac gcaagtccac atctaaagag tcggcaatca gttccatttt
    39481 atcggctttc ggattgtact gtcctgaaag ataggaactg aacgctcctt tgctgatacc
    39541 agtatctttg actatatcta cttgtttttt attttttgct ttcatggcaa atttaatccg
    39601 ttctgcgatt gtattcatct gaaaaccctc tctttccata tcccgttata acttttcata
    39661 tcttatcgtc taaggacact ataccacaag ttcagaaaaa agaaaataaa aagtttataa
    39721 aaaactaaac tttgtgttgc aaaacaaata tgtctgtgct aatatacaat taagtttaga
    39781 aataactgaa ctaaaacgac gtcgtaatag gaaaatgaaa atatgagaaa ctgacctatc
    39841 ggttcaacgg ggagaaagga acgtgtatgc agattacatt gacaaaagaa caggtaaaag
    39901 aagcatttgg agaacttcgt tttatgggtg cggataactg ttaccgctat gataaagaca
    39961 gtaagaagaa aacagaggaa gtggaagcat taaaacttca tcttggaagc atgaagcttg
    40021 ggaacagcgt ggatattcgc ttggaagcga cggaacttcc aaagattgag ccttatgctg
    40081 tggtggaact ggaagaatca gtatatgccc cttatgtgca gagaggaaac ttccctgtat
    40141 tagtggagaa gattacctgt aagggtatcc gccctgttcc aaacaaaaat atgtaggcgg
    40201 tcaaagttcc tgccctcgtt ctgacgtacc aaacggcagg ttgagggcag ggcaatggca
    40261 acgccattgc agataggagg tatgggaaat ttggaagaaa gaagcggaag ttttcttcca
    40321 gaactcccct atactaacag gggagtaata cgacagaaag aagcattaag tgccttgata
    40381 gactggtgtc agataaccat taaggaagtt ccgttagaag cagttataga agatgtgctg
    40441 agaatacctt tggaacttat gacggtaaca ggctatgaaa aggggattgc aggacatgag
    40501 gttgtggcaa tcttcgataa tatcaaagtg ctaaagccga caggaaatgc acagtatcaa
    40561 ggctttcaga ttttgatgag tgggaaaggt tgtcgcaact atgaaaattt tttacaactc
    40621 aatgaggaaa catggtttga ttttttaaac agagtttgtc agtaccacat caatgttcct
    40681 cggattgatt tggcgatcga cgacagaaaa ccgtatttga gtattcccga tttgattgta
    40741 cggacaaaag agggattgct ttccacaaaa ctaagggaga tagattttca cgactcggga
    40801 gagctgaaag aggaagtgtt tcagagtaag ggtggtagtc tttatctcgg cagttcagcc
    40861 agcaatttga gattggtatt ttatgaaaaa ggatatgaac agaataaaaa atatggaaca
    40921 gaattagacg aaaattggaa cagatatgag ttgagatttc ggcaggaaat ggcagtgagt
    40981 gtagtacagg aattattgag atatagagat gtggcaggac tggcaatgga agtattgaac
    41041 agcaaaatgc gatttttaga aaagccgaca gacagtatga caacacgaaa aagactttat
    41101 ccaacttatc aagcatgggc ggaactgatg aaagacatag gcaaggtcaa actcaccatg
    41161 caaccacaga agaaaagttt acaaaaggtg tggaagtggc tagaaaagta tgttgccccg
    41221 tctttgaagt tgtttgcaga ggttgggaag atagagcaga gagattatat cggtaatcta
    41281 gtgaaaaatg gagaaatgaa tatcgcacag aagcagttgt atgatgatta tataaaagca
    41341 agaaaattag acgaaagggg gtaatcgtat agaaaaggta ttattgaatt taaaagaggt
    41401 aagtgagtat cttggaattg gagaaacaaa aacaagagaa cttttgaggg atagaaattg
    41461 tccgttttcc atgaagattg gctatcggtg gtatgcgaat aaaaaaatat tagataaatg
    41521 ggtacaagaa caatcagaga aaaaaggggg aaattattct atttgatatg tatgtaagta
    41581 agtggtatag tgtaagagat aaaatgttct ataaagatat ttatatcata cagaaaggtg
    41641 tgtgatataa attgggtaag agtttaaaag gaaaagaatt aggtgcagga ctgtatcaaa
    41701 gaaaagacgg aaaatattgt ggtcgtttct atgaccgctt tggtattaga cgttatgtat
    41761 atggaaaaac catttctgaa acaaaagaga agttaaatac agcaatgtat gaagataaaa
    41821 tggaaatgaa tgttgccgat aatactgtga cattagatga atggtatcag aaatggttgg
    41881 aaatatacaa atacaaagtg attgcaccca gtacaagagt acaatatgag agcatttata
    41941 aaaagcatat acaaacagat ttcggacaca tgaaactgaa agatatacag cctttacaaa
    42001 tcagagggaa attagtaaat cttgataaaa agggatttgg atatgaaact cagaataaag
    42061 tacgtatttt actgttagat atgtttaata aagcggttgc ggacaacgtg gcaatgaaaa
    42121 atcctgtaag gaatattaaa gttgttcgag atgaagaaaa agaacctcgt gtactgtcaa
    42181 cagaagaaca atctgccttt tttgacacct gtaaaggaac attttacgat aatcttttta
    42241 atgtggcaat atcaacagga cttcgccccg gcgaattata tgctttagaa gctgaggact
    42301 tggattttga gaaaaaggta atacatatta caaaatcgtt atcctatcag aaattcgagg
    42361 gagatacagg aaagactttt cacatgggaa aaacgaaaac gaagtccagt tatcgtgatg
    42421 tgcctatgaa tagaagatgt gaaattgcat taaagaaaca gttattgcag aaaagagttg
    42481 tttcgggtag aaatggtgca aaaacattaa aaggatttga aaatttgatt tttacaacaa
    42541 aatatgatac tcctcttaat gcacagattt atgcagatgc tatcaaggta atcgttgagc
    42601 aaatcaatct tatgcgagag gaattggaac aatttgaaac attttcgggg cattgcttta
    42661 gacatacatt tgcaacaaga tgttttgaag caggaataca gccgaaaaca gttcagaaat
    42721 atctaggtca tgctacatta caaatgacaa tggatttata cacccatgtg ctagaaaacc
    42781 atttatcaga tgaaatggat aagttagata gcaggctgga aatgattgaa ctttcaagtg
    42841 atgatttagc agagcaacgt tttgaacggg aatataggaa acagaacgaa gttttgtcct
    42901 ctgataagtt aatacgcata ggataaaagg gagtataata ggagtaacag aaaatgctat
    42961 gggagtacaa agtgcttgaa aatggcttaa ataaaggaaa aatcaagata tgatttgtac
    43021 tccctagttg ttttattata ttattcatac ttaggatgcc taaagatgtt aatgaaaaag
    43081 taaaatctaa aggtaaaaaa gagaaagcat ctgatacaat ttctccttcc gtatggggtt
    43141 atacattaaa agaagctaaa aaaattaaat atttttggat tatgacgatt ggatttatat
    43201 ttgttggtat atatgtttcg tcattatctg tacaatatcc aacttatctt agaaattatc
    43261 taaatcctat tctaatagga acagtaggct cgacatttgc tttatttgct ctcattggta
    43321 atttatttgg aggattattg tttgataaat tcggtcaaat aaagccactt attatatctt
    43381 ttgtattggt tcttatagca actttatcat tactattggt agataaatct tctgcttttg
    43441 catttgtatt tgccattttg aaaggtcttt ctgtatttgc ttatatgatt ggtcctgctt
    43501 atttaactgg cactttcttt ggtcaaaagg aatttggtag catatatggt atcgtacaat
    43561 taatttttgc agtgggattt gcattaggtt caacattatt tggattacta gttgataatt
    43621 ttggatatag attttcttgg tctattataa ttttatcagt tataattgcc tatactttac
    43681 ttattataac ttctatagga atgaaaaaat tgaataaaga aagactagat aaactgatgc
    43741 aataatcgat ttttagatat ataaatatta tatgaaaaag atggagcttt taatcataaa
    43801 taaaactcca tctttttata ttacaatata gctaattttc tcttattttt aactttacta
    43861 tctatatcct catccttaac tatagtaaat gccttagttg gacaaacatt tacacatgca
    43921 ggtccttctg gtgattctat acaaaaatca cacttatttg ctgtcattct ttctctaaaa
    43981 caaagctttc cttcatctac atcttttaat gtaactatgt ctattgcacc tataggacat
    44041 gctaacatac aagtcttaca tcctatacaa ttttcttcat ttatttttat tgtgttccca
    44101 accctaacta taccaccatt tggacatgcc tttgcacaag gagcatcttc acaatgtcta
    44161 cactgtattg gagcacttac ttcttttgtc tttatgacag aaagttttgg attaaaattt
    44221 atttcatctg gattttggta aaaaatatct tcatctgaat gtgcaactac acatcctatc
    44281 atacaagttc tacatcctat gcatttatca gggtctgcta taacaaaata gttcatcact
    44341 tagccacttc ctttcctata caatatgtag tgtgtaatag atgatgagat ttttctccta
    44401 atggttctac caaatattca tcatatagtt ttttaatatc agggttctca tgagattttc
    44461 taattgctaa atgttcatca tgcacatacg ttgcttttgt tctattttca taggccaatt
    44521 ccttatattc ttctagtaaa atttttggct gacctccacc gcttacacac ccaacaggac
    44581 aagtcataac ttcaataaaa tctacatcta attttccttt ttccaagtct tcaagcactg
    44641 gtattacatt ttttaatcca cttactactc caactcttaa gtctaagtct cctattttaa
    44701 tagttgactt tctaaaacca ttttctcctc ttacttgttt tacttctaca tcaggaatac
    44761 tttctccagt tataagctca tatcctgttc ttatagcagc ttccataact ccaccagtaa
    44821 caccaaagat agttccagct ccactataac tacctaaagg gctatcaaat ttttcttctc
    44881 ttaaattttt gaaatcaatt cccatgtctt ttattaaata cgctagttct ctagtagtta
    44941 acactacatc tacatctcta tatccactag aatccatctc ttctctatca cattcatatt
    45001 ttttacatgt acatggcatt atagaaacac taaatatctt tgatgcatct acattattta
    45061 tctctgcacc ataagtttta aatattgcac cacccatctg ctgaggtgat ttacaagaag
    45121 ataaatgatt agttaattta ggataatttt tttccatgaa ttttacccaa gctggacaac
    45181 aagatgtaaa cattggaaga gttccacctt ctgtcaccct tttaattaac tcactacctt
    45241 cttccattat agttaaatct gctgcaaaat tagtatcgta aactctatca aaatttaaag
    45301 ctctaagtgc tgctgccatt ttcccagcac ctaagtatcc taaataatat ccaaaatctt
    45361 cccctaaagc aactctaact gctggtgcac actgaaccat agtaaataca tttgggtcac
    45421 ttaaagcttt tttaacctta tctatatcac atacattgta tgctgcaaat ataggttcat
    45481 ttatagactc tggtatctct ctttcttgtt ttttctcttg caaaaactca aatccttcat
    45541 ctataactga ggcataagat ttacaagttt gaacacattg accacacata acacatctat
    45601 ctaaatttat ctcttgtggc tttccctctt caccttcaat agcatttact ggacagactt
    45661 ttgaacattc tctacatcca gtacataaat ctttatctat atttattatc ataaacgtca
    45721 cctacccctg tatcctttat ttatttgtta acaataagct aagtgcagct tgtctattct
    45781 tagctttttt gtcatctatt ggagtaacaa gttttaatgc ttcctgagga catgcactta
    45841 tacaagctat tttttcactg tctttacata agtcacattt ataagctatc tttttatttt
    45901 catctaaaat tacttgttct acttctttac catcttgata ttgtggaagt aaatctatag
    45961 ctccaaaagg acatgctaac agacaagttt tacatcctat gcacttttct tcatttacag
    46021 acataatatt attttctttg attatagctt tttgtggaca tgagtttaaa caaggagcat
    46081 cttcacagtg tctacactgt attggcatac aaaaattgtc accttttact aaataaagtc
    46141 taggtataac aggtatatca actgttccta ctgtataacc aacattatta tgctgattat
    46201 gcattgtaaa acaagctact tcacaagctc tacaacctgt acatttgttt gggtctgcta
    46261 ttacaaaaga gcctatttta tttttcatat tatcccacct ttcaatttgt atatttccaa
    46321 ccctctagtt accttcatca tatatattta tatattttaa tattttctca atactcatat
    46381 ttcgtttaca ttttttgcac aaattgtatg tgttgttata caccttatca gtatcattaa
    46441 ttaatactcc gcagatttca cactttgaat attttagctc ttctttttta gtacacatat
    46501 actcattctc actttttgat aactctctgt ggatttgcat aaatattcat ccgtcttcct
    46561 cttacaaatc caataagggt tatatttaat tttttagaaa gctctattga taaattagtc
    46621 ggtgctgatt ttgatactac aataggaatt tgagtcatag ctgcctttaa tatcatttcc
    46681 aatgatattc ttccacttac agctacaatt ttatctttta atgctatatc atttaaaaca
    46741 caaaatccaa tagccttatc cattgcatta tgccttgcta catcttcaca agtaactatt
    46801 cttttatcaa aattaaatat ggatacacta tgtactccac cggtattttt aaataactct
    46861 gatgaattta aatttctatc cattatactg taaatcgtat cataatttat ttttatattg
    46921 ctctctacag gagcacatgt tatatagtct agtgaattta aaaatataat ttgctcattt
    46981 tgattttttt gcttctcatg aatagttact tttgcaaaac gttcactctc atttatctca
    47041 aattttaata agcttttttt attttctata tatccttttg ttttcaaaaa tcctactata
    47101 agctcctcta aattagatgg tgtacataaa aatgtattta tatatttatt atttaaaata
    47161 aaactaagtg gatattctgc aattatttct tcattatcta ttgatacttc atgttcattt
    47221 attttactta cttctacatt aaaagaattt aaatatttgt gctccactag actataacta
    47281 ttttcaaaaa ctttatcctt actattttgt tgtaatttag tttttgagta tatattgttc
    47341 ataaaatatt agcctttctg aattttataa atctttaatt taataaatca ttagatattt
    47401 gtagctgtca ttttatcttt caaactttta tactcttctc ttacacattt ctctgctaat
    47461 tcttggtctt caagtttttc aagcttaaca gcacaatatt tatactctgg tgttttagat
    47521 atagggtcta aatttgctat tgtaagttca ttacaagccc caacccacca ctgataagtc
    47581 atatatgttg caccttcctt aactctatca gtaactgttg ctcttgttat tacacttcct
    47641 cttcttgaac taattctaac taattcatca tcttcaattc ctaatttttt agcatcatta
    47701 gaatttattt gaacacgccc tggttcatct tctaatgaac taagtgttct gcaattacca
    47761 gtcattgttc tcactgaata gtgtccaact tctcttacag tacacaaact aaatggatac
    47821 tcatcatctt caacttccat aggaggtctc cattcagcag caaacaaatt acctttacca
    47881 ttaggagtag aaaacttttg accttcatat agatacatag tacctttatc ttccatgctt
    47941 tcgctcttac aaggccattg aacacaccct tgagcttcta tcttttcata agtagcacct
    48001 aagaaacttg gacataattg tctaagttca tcccatattt ccttagtatt tttataattc
    48061 ataggatatc ccattgctgt agaaatttcg cttataattt gccaatctgg ttttacatca
    48121 ccttgtggct ctatagcctt tctcatcaac tggaatcctc tatctgcaca tgtatatact
    48181 ccctcatgtt ccccccaaga agtagctgga agtataacat cagcatgaag tgctgtctta
    48241 ttcataaata tatcttgaac aatgacaaac tccaattcat ctaaagcttc tctaacttct
    48301 gatgcatctg ggtcactttg cactgggtct tctccaaata tataataagc tttaagcttt
    48361 ttctctttta gaactaaatc tggaacttga gttaaactat aaccattatt aggagatagt
    48421 tttactcccc aggctttttc aaacttttct cttatcttat catcagttac attttgatag
    48481 ccaggatata cattaggaag agctcccata tcacaagctc cttgaacatt attttgtcca
    48541 cgtacaggtc ctattccaac gctttctcta ccaaaattac ctgtaagtag agcaattgat
    48601 gcaagtccct taactacatc aacagcttga ccaaattgac agacacccat tccataaagt
    48661 atcatagctt ttttgccttt tgcatattcc ctcatagctt ttcttataag ctcttctggg
    48721 attcctgtaa tcttttcagc atatttagct gtatatggtt taacaatttc tttatactca
    48781 tcaaatcctt gtgtatgatt ttgaacaaat tctttattgt aaagaccttc ttctattaag
    48841 acatttccaa aagcatttac taaaaccatg tttgttccac cttttatagg tagatgtata
    48901 tcagcaattc ttgcagattc agttactcta gggtcagtaa caattaattt agcaccattt
    48961 tttttagctt ttactattct atttgccact attggatgtg aatctgctcc attatatcca
    49021 aatataaata aaacgtctgc attttctatc tctggtatag aattagacat tgcaccacta
    49081 cctaatgagt aagccagacc ggctacagat ggtgcatgtc agacacgagc acaatggtca
    49141 acattattag ttcctattgt agctctcata aatttttgca ttatataatt tgcttcatta
    49201 ccaggtcctc ttgcagaacc cgttcccata atagaatcag gtccatattt ttctttaatt
    49261 tcatttaatc ttgaagctgc atagtttata gcctcatccc attcaacctc ttctagtaca
    49321 ccttgttttc ttatcattgg cttttttagc ctaggtgtta gaattttagg gtcatttagg
    49381 aaatcccatc cataacgacc ttttaaacac aaactttctt gatttgttct accattagct
    49441 ggttcagctc ttaatatctt attatctttt actactagat ataattggca tccagctcca
    49501 cagtatggac aaactgttaa aatttttttc tccatacaat tcccccctta gatttatccc
    49561 ctgataagta aaatttatct taaagataat gagtgttttt ataatatgca aaatcataaa
    49621 tattttgcaa tactatctat taaattcaac aattttctca caattccttt taaatttcaa
    49681 aaaaaatatg tcataataat ctttatattt caaccattta attaaaatat tctagttctt
    49741 atgacatatt ttttaatata ctcaatatat attatttaaa cttatttagt tttcacttaa
    49801 aacaatattt ctgccaattc tatttttcat tctatagtga gtaattacag taaatattcc
    49861 acttccaatc agaatcaaat agtacataaa tccaccatat aaaaataccg catatcccat
    49921 caaaggttga gggaatactg atttaaatat agtaaaaaat gctaattcat tagctcctac
    49981 atttccaggt gttggtattg gagaaattgc catatataaa aatgcttgta atgtaagtat
    50041 atagatatag ctataacctt gtaaattaaa tgctttatat atccagaatg aaacactaaa
    50101 gtaagcactt aattgaataa aagttactat tatagttgaa attaatactt ttttattctt
    50161 tgcaaaaaaa tttattgctt tactataatc atctataaaa ctttctatag attcaatctt
    50221 attatctaaa aattttaaaa acttaatttt tgataaatgt tttatagtaa ttctcataaa
    50281 atattttatt ttttgaggat ttaaaataac taatattatc ataattaaga caaatgaatt
    50341 aatggctatc cctagaaaca ctagaggcat aatcattttc atttgttttt ctaacatagc
    50401 aaaattcatt aatacaagta ttgtacaata aaaagtaacc actatttgga aaataataga
    50461 cttattggta acaactgcac ttgccttact aagtggcatt ttacattttt taagtacata
    50521 tatctgtact ggttggcttc ctgaagcaaa aggagttatt aaattataat aaaatcccat
    50581 aatggctagc ttaaagccaa taaatctaat attaactttg tgagtgcttt ctataattat
    50641 cttcattact actccttcaa gcattatgtg acacattatt gccaaagcac ctatgaataa
    50701 aaacttctta tctaccataa ccataacatt tgatagcatt ttaatatcca atgttttaaa
    50761 cactaggtaa attgttatac ctattaacaa aaataaaaat gtatactgta gtaaactttt
    50821 tctaatactc tttagtctat ccattagaaa taaccatcct ttgttcaaga tttatactaa
    50881 atactatatt attagtatat actatgaatc ttaatatttt ataacaaaat accttacaat
    50941 tttgtcattt acaaaaaata ttaatctata tattaaattt taatatatag attaatattt
    51001 tacaaacatt ttgtagatat atataatatt ttcactaaac agcaattatc tttattacac
    51061 ccatttatac cctatccccc atacagtttc tattgtataa atatcatatt gttttaattt
    51121 gcttcgtata ttttttacat gctctgtgat agtacttata tcactttctc catcaaaacc
    51181 atataccgac tcatatattc tttcttttga aaatacttgt cccttatttt ttgctaaaaa
    51241 ttcgcatatc agatattcac ttttagtaaa attaattttt ttaccatcaa ttaaaacttc
    51301 tttacccaaa aagttaaatt gaacatttga gatagttaat aaattctttt tttctctact
    51361 ttctctcctt aaatgagcag ttattctagc ccttaattct cccacaccaa aaggtttggt
    51421 tatataatca tctgctccta taccaagacc atacataata tcactttcca tatttttagc
    51481 tgtcaaaaac agtattggac aatcaacctt atttcttata gctttgcaca cttcaaatcc
    51541 atccatctta ggcatcatta catctagtat tattagatta aaagaattaa attcaatatc
    51601 catagcattt tctatatcac taatcacctt tacttcatgt ccatctcttt ttaatacatt
    51661 ttcaatcaac tttaacacat ctaactcatc atctattacc agtattttag acacactaac
    51721 tcctccattt gcatgtttaa taacatttta atacttatac ttaattactt ttttcaattt
    51781 tatatgaatc attatactct catattatat cttacaataa ctgattgatg ttttacaaat
    51841 aaaacatttt agactcaaaa ctttatatgt aaaatattct atacttattt tatatatgtt
    51901 tatttaatta taaaaatgta tttgataatt tattattgta atattttaaa aatgtaataa
    51961 aatcaataat aagaaaacat cttataaaca tatctttaat tatttaaatt ggaggaaaaa
    52021 attatggatg aaaagataag aagcagtaac tataatgttc catttgacta tgctagaaaa
    52081 aaatttaaag aattagaccc tcatacaatt agtaatttga gtaatatttc tttcaacaat
    52141 gattcaaaca agttcatact caatttcttt gatagacaat atattataga ctatccaagt
    52201 ggagaagttt ggaatgatga tggtagtatc tgtaaaaact tcgaacttaa aattttaata
    52261 attagatact taactaatgc taaaggtata cctagaacta ataaatatgt gacttttaag
    52321 gaaataccag gaggaaatgt ttactatcca aactttttaa acagaacgct gtctagactt
    52381 tcggaagttt ttacatgtca aatagacaaa tacaagttgg ttatggaaaa tatgggagct
    52441 gaaaaagtag atatgggtga cttagcctat aagtttacat atatgggtaa tacatctatg
    52501 atatttatac tttggtttgg agatgatgaa ttccctccaa attcaaatat attatttgat
    52561 tctaatataa tttattactt caatgcagaa gatttagcag ttgttcctga tacagctata
    52621 gatgcaattt taaataaaat aaatcaatta taaatataaa taatattatc acacaggtat
    52681 gataatggtg cagattattg gactattaaa aaacctagaa aaataatagt tatatagata
    52741 aaacatatta aaaaatagtg gctttaaatt ttttaaagtc actatttttt taaaatgatg
    52801 ttcctgaaaa tatattaagt tagttattct actactgaac ctcccatgac taaagtcaca
    52861 gggttcctgc ttcatagaat tttgcatact aaaatatgtc ttactaattc tccacaggct
    52921 atcccc
//
LOCUS       DAMKOJ010000021        51498 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000021 DAMKOJ010000000
VERSION     DAMKOJ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.022"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            85..423
                     /locus_tag="PC592_001330"
     CDS             85..423
                     /locus_tag="PC592_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HDF4055322.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(548..1837)
                     /locus_tag="PC592_001331"
     CDS             complement(548..1837)
                     /locus_tag="PC592_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF4055323.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPSIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKNLPQIDGSSMYLKEGE
                     SFTVKQLLNALLVHSANDAAFVLARYVGGGDVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELVYEPKNSYRIFLEKNESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNIYNNGKLENSIDLIAKNNLDSSIPFLTGNNILMT
                     FVKIIAGILVLLVLFIITSNIKRKKRKKARSKRNMKK"
     gene            1917..2621
                     /locus_tag="PC592_001332"
     CDS             1917..2621
                     /locus_tag="PC592_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDF4055324.1"
                     /translation="MKKKVKFISFFILFILIISSIIVYKSLIFKDDIYVVSKKVSSNE
                     KTHAVEAEIKNEDNSHNKATKDIDKNFQNNKITIYISGAVNRPGIVTIEPDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEAISVTSNDDSNKSNQKNESRSEPK
                     NKSNKNISNKSKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            2713..3759
                     /gene="selD"
                     /locus_tag="PC592_001333"
     CDS             2713..3759
                     /gene="selD"
                     /locus_tag="PC592_001333"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2761..2763,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDF4055325.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFAKVKESGALLVGGHTVDDKEPKYGLSVSGIVNPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFDK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGTIEMAQMGIIPAGMYKN
                     MHYVSKDVEIVGNVEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            3777..5189
                     /locus_tag="PC592_001334"
     CDS             3777..5189
                     /locus_tag="PC592_001334"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDF4055326.1"
                     /translation="MIILSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDISNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVIAITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVDELRKAFN"
     gene            5303..7186
                     /gene="selB"
                     /locus_tag="PC592_001335"
     CDS             5303..7186
                     /gene="selB"
                     /locus_tag="PC592_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDF4055327.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNESSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIENGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKKALETLISGDKVFIIGNMYMHVNQYNKLKENTIKLLS
                     EYHKKYRLRKGMLKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNEKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNTLINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            7291..10029
                     /locus_tag="PC592_001336"
     CDS             7291..10029
                     /locus_tag="PC592_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HDF4055328.1"
                     /translation="MKSIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDTDKYETLL
                     HTIYTIFLVATGVIVFNTTKFKVDSFSTFLGLIFIATGALECIYLFNSLEIKTQFVRE
                     LNITISAITDLFPILGVYLSFKFVKDNKQIYSSIILFIVTVTLTIISLFIISGICEYL
                     GNGTSQYALEVIISIFIIIISIVSGIELNLSSSEGKWEYNEKKIFNRIIVIIILSRVP
                     NLLHIVIDDRNIERILSHIIINVAIYYLYNYIVSKNIKKTALELHDINEELTLKTESL
                     KEKNKKLIYETEKIEELKGILIKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESINYVFVYEKNVEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSREFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTDKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYNDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRSEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTELEEINIYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVISEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(10148..11092)
                     /gene="manA"
                     /locus_tag="PC592_001337"
     CDS             complement(10148..11092)
                     /gene="manA"
                     /locus_tag="PC592_001337"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDF4055329.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGIYKGKKLSELWDKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVDMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNLGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFRCTTFVSNEFFSVYKLDIFGKCTFTHKTPFSLYSVLDGNGK
                     LIHNAVEYNLKKGMHFILPNNFGEFGFEGNLEIICSHI"
     gene            11265..12626
                     /locus_tag="PC592_001338"
     CDS             11265..12626
                     /locus_tag="PC592_001338"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF4055330.1"
                     /translation="MELFKEEIKKYEKEFLKLLEEWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLLSNIDDKSLYISGGIEFNTIPDKVYI
                     KNIEKLGKDNICFDINKISISYDNDNYIVHGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSARYPEIL
                     SIEEIMKKFNLYMEKNNINKFELIGENLKQANYIDKNSKLVKSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHGANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            12714..14603
                     /locus_tag="PC592_001339"
     CDS             12714..14603
                     /locus_tag="PC592_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4055331.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIDSSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIYCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIESLMKEISDKIGFKLIEDEVIYISNYSGV
                     IACKGTQGIKNTSELEERINSVMSSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFNIKANTK
                     EEVILSLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            14618..15073
                     /locus_tag="PC592_001340"
     CDS             14618..15073
                     /locus_tag="PC592_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055332.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKELNLAEDESLVY
                     EGLMSREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKDFKDSLLKSDNVEEISNLINEALGL"
     gene            15131..15448
                     /locus_tag="PC592_001341"
     CDS             15131..15448
                     /locus_tag="PC592_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF4055333.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            15473..16735
                     /locus_tag="PC592_001342"
     CDS             15473..16735
                     /locus_tag="PC592_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF4055334.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKKLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAVWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            16840..17904
                     /locus_tag="PC592_001343"
     CDS             16840..17904
                     /locus_tag="PC592_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF4055335.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     EAQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIIDFIKVGMTE
                     KQVENEIVRVIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITKDGCMRLTTSTKDLIVVS"
     gene            17958..19136
                     /locus_tag="PC592_001344"
     CDS             17958..19136
                     /locus_tag="PC592_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF4055336.1"
                     /translation="MYNFDNKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVDVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEAQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTKVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIEKELLENVILLTSPNKGFNLGGLKTSYSIVINKNIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLNGVNEYIKSNYELLETWVNKYSKIKLMKMESSYLAWMDISGL
                     GISASEFTDRLAIDTGVLLEDGSHFVQDGDKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            19332..19529
                     /locus_tag="PC592_001345"
     CDS             19332..19529
                     /locus_tag="PC592_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005809912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055337.1"
                     /translation="MKNCVEALRKKKGLNQEDFAKILKVSRQTISSIENGKYNPSLEL
                     AFQISDFFEMSIEEIFLWKEI"
     gene            19533..19967
                     /locus_tag="PC592_001346"
     CDS             19533..19967
                     /locus_tag="PC592_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurium resistance protein TerC"
                     /protein_id="HDF4055338.1"
                     /translation="MEKRNLRIGIVYVVLGVTFLFSCLMTKDKLSSLLVGLAAGFGFN
                     GISIIYRYFYWNKHKEEYREKLEEEKINLQDERNVMYRDKAGRYAYIVCMIIIPISAF
                     VFAVLNALDIYNSLVIIIYLSVLWIVLYVVGVIYYRKLKNNE"
     gene            complement(20143..21198)
                     /locus_tag="PC592_001347"
     CDS             complement(20143..21198)
                     /locus_tag="PC592_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDF4055339.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSGQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVKVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLNKENMKIDLGAIAKGYAADKIVSYLKSEDIKKGLVNLGGNIFTLEDSKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINRIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKAFSIEKLNK"
     gene            21265..21636
                     /locus_tag="PC592_001348"
     CDS             21265..21636
                     /locus_tag="PC592_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDF4055340.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            21673..22347
                     /locus_tag="PC592_001349"
     CDS             21673..22347
                     /locus_tag="PC592_001349"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDF4055341.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            22595..23434
                     /locus_tag="PC592_001350"
     CDS             22595..23434
                     /locus_tag="PC592_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF4055342.1"
                     /translation="MNFKKLSNVKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDKNAKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            23676..23772
                     /locus_tag="PC592_001351"
     tRNA            23676..23772
                     /locus_tag="PC592_001351"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23710..23712,aa:Sec,seq:tca)
     gene            23923..24630
                     /locus_tag="PC592_001352"
     CDS             23923..24630
                     /locus_tag="PC592_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDF4055343.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NQDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIINELLGQ"
     gene            complement(24772..25608)
                     /locus_tag="PC592_001353"
     CDS             complement(24772..25608)
                     /locus_tag="PC592_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4055344.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEYSKNIINSYLRQKRIKTIDIIIATHPDSDHIGSLDNVIKKFNVNSIY
                     MPEQSTNSESYQNLINSCTDKNLAIQYLYKDDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNNNSFLFMGDAEEENEKEILRSFELNNINFIKIGHHGSNSSSSLEFIKKIN
                     PDIAAISCGYKNQYGHPHKEVIDNLKQSHVSIYRTDRIGDIVFYSDGEIIFTKYNYEV
                     DT"
     gene            25795..26700
                     /locus_tag="PC592_001354"
     CDS             25795..26700
                     /locus_tag="PC592_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HDF4055345.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPDRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYESKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            26709..27893
                     /locus_tag="PC592_001355"
     CDS             26709..27893
                     /locus_tag="PC592_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4055346.1"
                     /translation="MEIRYAKEEDIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNNKVYNTSYVVGVSTLPEGRGTGYMSKVIKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     RIDRAFLNEVNGNVLKDEHYYKNLFKEIQSEDGFLYIHEGNEKDGYIVYFINEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPIIDKIRFILDNPKDSEIKIKPFMMG
                     RIINVKKFIEDVDIENDINSSFNLLIEDKFINENNGLFKISIQNKKVSVEQLYKKDEE
                     KPQEDFDVKLDINTLTQLAFSYIDVNEAIFLNDIKDVSEETLEILNCIFSKKNNYINE
                     YI"
     gene            28008..29309
                     /locus_tag="PC592_001356"
     CDS             28008..29309
                     /locus_tag="PC592_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDF4055347.1"
                     /translation="MGVIIIQIRRPLLIILVFVIAISFIITNNTKNNEEINDKIITIQ
                     GIVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKFYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLSEEQKEIFTRTGTSHVISISGLHTGILCIIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIIYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIEKPKF
                     YIVIIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKF"
     gene            29263..30306
                     /gene="holA"
                     /locus_tag="PC592_001357"
     CDS             29263..30306
                     /gene="holA"
                     /locus_tag="PC592_001357"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF4055348.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGSNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(30496..30762)
                     /gene="rpsT"
                     /locus_tag="PC592_001358"
     CDS             complement(30496..30762)
                     /gene="rpsT"
                     /locus_tag="PC592_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDF4055349.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            31084..31713
                     /locus_tag="PC592_001359"
     CDS             31084..31713
                     /locus_tag="PC592_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4055350.1"
                     /translation="MNLIKNYKNTEDTADKLISYIDENCSGHLFALCGVSLGGQIVME
                     LLSRKPNITKKAIIDGSICYPRPLMARFCITGIRFFGGLLFSKKACRFQIAMMPKLLP
                     ENMQYPDEIKAYYMTDMPHVRKETFYNMYRTYMMNYILKENVKKTTAQVMYWYGEKEM
                     KCVKKSAKMFQSYVPSCEIYEAKGYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            32055..33008
                     /locus_tag="PC592_001360"
     CDS             32055..33008
                     /locus_tag="PC592_001360"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HDF4055351.1"
                     /translation="MINVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDEQGSEIMNKDIGKYITLESNLMKFDDDESREEMISYLKDELVDIFGQDENKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            33026..34045
                     /locus_tag="PC592_001361"
     CDS             33026..34045
                     /locus_tag="PC592_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HDF4055352.1"
                     /translation="MFKKCIKVVTLTFILACILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTEDKKNNKNKETSKENKEESKEEKTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNATSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            34076..34327
                     /locus_tag="PC592_001362"
     CDS             34076..34327
                     /locus_tag="PC592_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055353.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRIMFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPNIKFDITKFDFDIPNFDIHEIIRKFNK"
     gene            34609..36414
                     /gene="lepA"
                     /locus_tag="PC592_001363"
     CDS             34609..36414
                     /gene="lepA"
                     /locus_tag="PC592_001363"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDF4055354.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            36563..37900
                     /locus_tag="PC592_001364"
     CDS             36563..37900
                     /locus_tag="PC592_001364"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDF4055355.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMVEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSETGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFNIDEGTEQSIHKKSDLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGHILNNMLEIVINNPELNEKEILKEKALNIYTF"
     gene            38133..39446
                     /locus_tag="PC592_001365"
     CDS             38133..39446
                     /locus_tag="PC592_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF4055356.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIIFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITMGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKALLKVNSGGSPVNSI
                     LLITALACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLYRPYRVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            39618..40793
                     /locus_tag="PC592_001366"
     CDS             39618..40793
                     /locus_tag="PC592_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDF4055357.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDLKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFMSIKEMFYIDDN
                     AEITIECNPGTLTLEKLKTMKDIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENIDIEMYEYTINYLMSKGYNQYEISNYSKEGFNCKHNILYWECKPYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFKDKYSKQIEMLSARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            40896..41915
                     /gene="hrcA"
                     /locus_tag="PC592_001367"
     CDS             40896..41915
                     /gene="hrcA"
                     /locus_tag="PC592_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDF4055358.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLVNQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            41945..42565
                     /gene="grpE"
                     /locus_tag="PC592_001368"
     CDS             41945..42565
                     /gene="grpE"
                     /locus_tag="PC592_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDF4055359.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSNEKT
                     DEKEVDDENVTDINSKLAEKKLQNELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGIEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            42657..44504
                     /gene="dnaK"
                     /locus_tag="PC592_001369"
     CDS             42657..44504
                     /gene="dnaK"
                     /locus_tag="PC592_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDF4055360.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSSEKEEIEKAIADLKTVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            44715..45869
                     /gene="dnaJ"
                     /locus_tag="PC592_001370"
     CDS             44715..45869
                     /gene="dnaJ"
                     /locus_tag="PC592_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDF4055361.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRTRRRGPQRGADIRQSVTIYFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSTCNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            46844..47779
                     /locus_tag="PC592_001371"
     CDS             46844..47779
                     /locus_tag="PC592_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF4055362.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            47812..49185
                     /locus_tag="PC592_001372"
     CDS             47812..49185
                     /locus_tag="PC592_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4055363.1"
                     /translation="MSKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMYLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGRWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(49373..50140)
                     /locus_tag="PC592_001373"
     CDS             complement(49373..50140)
                     /locus_tag="PC592_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4055364.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNSIYVIDF
                     LDKNNLDNLKGNFYLIYQPHIEFEYLKNIFYNLFEDINIIQHNSFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGLKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(50170..51279)
                     /gene="ugpC"
                     /locus_tag="PC592_001374"
     CDS             complement(50170..51279)
                     /gene="ugpC"
                     /locus_tag="PC592_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDF4055365.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYDNMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVTLIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRIHIFDKETTLAIR"
BASE COUNT        20382 a         5474 c         8775 g        16867 t
ORIGIN      
        1 tattgacaaa attattttta gatactatta tatataatat aaataataat gaaaatcaat
       61 gtcaattaaa tgggaggaaa tctaatgaac ttattagtga ttggtggtca tgaaagaatg
      121 gaaaaggatt atatggttat ggccaagaaa aaaggttata agacaaaggt atatactact
      181 atgtcatcta aattaaataa ttctatagga agaccagatg cagttgtcat acttacatca
      241 actgtttcac ataagatgtc tagaacggtt gagtctcaag ctaaaaaaca agatatatta
      301 atcgtaaggc ataaaaatag cagtaaagta gcctttaatg aatgtttaga tatggttgat
      361 gaatgtctgg gaaattgttc aaaatgtaag cttaaagata aacaaaaaca aaaaaatata
      421 taagtataaa aaatacataa acataaaatt aaaggtactg agataatagt tataattatt
      481 atctcagtac ctaattttat aagtagaagt atattataaa atttttatta taatttctaa
      541 ctaattgcta ctttttcata tttcttttac ttctagcttt ttttctcttt ttcctcttta
      601 tatttgaagt tattataaat aaaactaaaa gtactagaat acctgcaata atcttaacaa
      661 aagtcattag aatattattt ccagtcaaaa atggaatact gctatcaaga ttattttttg
      721 caattaagtc tatactgttt tccagtttac cattattata tatatttaaa gtaccaacct
      781 tagcaccttt ttttataggc aaatcaattt tatttaactc tgttttggta tcatagttgc
      841 cttgagattc atttttttct aagaatatcc tataactatt tttgggttca taaaccaatt
      901 catgctgttt tgtaaataat acttttttag tatctgtgta tttttcttta tcaacaatag
      961 tagcacactt aaagttatca aatccataat caataagaat acgtgagtct aaatataaat
     1021 cagcattagt tgaattaaat acagcaacga taactcttct gccatctttt acagcactag
     1081 ataaaagaca tttaccagca gcatcagtat atccagtttt tataccatca actatatcat
     1141 attttatatt tataggttga cctttgtatg taatcttatc atgtgatgtc aaaaacttat
     1201 tagtgtttac aaagtatctc tcataaggat atgcttttgt tgcttcaaat ttaagtgact
     1261 tagtttttac aatttgtcta aaagtatcat tattcatagc ttctctagct atgagagcca
     1321 tatcatgagc tgttgtgtag tgatttgggt ctggtaatcc atgaggatta ttaaaatgag
     1381 tattagtagc tccaattttt tttgcctcag agttcataag gtcaataaat ttttgtacat
     1441 cgccaccacc aacatatcta gctaatacaa aagcagcatc attagcagaa tgaactaaaa
     1501 gagcatttaa taactgcttt acagtaaaag attctccttc ttttagatac atactagaac
     1561 catctatttg aggtaaattt ttaatttcta ttacttgatt taaatcttta acctccttta
     1621 aaactaaaca agctgtccat actttagttg ttgaagctgg ataaagctta gaatttccat
     1681 ccttattata taatattttg ccagattcat agtccattaa aactgcatgt ttagcaacaa
     1741 tagatggttc attatctgca aaagagatat tagagcttcc taaaaatgaa gtaaatatca
     1801 ataaacagat taataaaagt gataaatttc ttttcattgt gagcctccaa attttaaatt
     1861 catcttttag tatagcatat atttgtcaat aattaaaaga aaggagtgat taatatatga
     1921 aaaaaaaggt aaaatttatt tcatttttta ttttgtttat tttaataata tcatcaataa
     1981 tcgtttataa atcgcttatt tttaaagatg atatttatgt tgtaagtaaa aaagtttcgt
     2041 ctaatgaaaa aacacatgct gtagaggcag aaattaaaaa tgaagataat agtcacaata
     2101 aagcaactaa agatatagat aaaaattttc aaaacaataa aataactata tacataagtg
     2161 gagcagtaaa tagaccaggg attgtaacta tagagccaga caagagactt tatgatgctg
     2221 tagaattact aggaggaact acaaaagaag ccgatttaaa tggagtcaat ctatcagtaa
     2281 gattagaaga tgagcaacat tacataatac ctaaaatagg tgaagcaata tctgttacaa
     2341 gcaatgatga ttccaataaa tcaaatcaaa aaaatgagtc aagaagtgag cctaaaaata
     2401 aatctaataa aaatatatct aacaaatcaa aagtaaatat aaatgtagcg actatagaag
     2461 aattggattc tctacctgga gttggagaag ctacagccaa taaaatttta caacacagag
     2521 aagaaaatgg acagtttagt tcaatcgagg aaataaaaaa tgtaaatggt attggagata
     2581 aaaaatatga aaatataaaa gatttaattt gtgtagacta aaatataata caaaacatac
     2641 ttatagatat ggtattataa atatgtatgt atatgtgtgt atatgtggaa atttagtaaa
     2701 ggaggcactt ttatgaaaaa agaacaaaaa aaacttacag agatgacaac agcaggtggt
     2761 tgagccgcta aaatagggcc agaggttctg gcatcagttt tatctcaatt gcctaaaaat
     2821 gataatatag aaaatttatt agtaggacta gatacagcag atgatgctgc agtttataaa
     2881 ttaaatgatg atatggcact tattcaaact ttagacttct ttacaccaat ggtagatgac
     2941 ccatatgtat ttggtcaaat tgctgcatca aattcactat cagatgtata tgctatggga
     3001 ggcaaacctt tggttgctat gaatattgtt tgttttccat catgccatga tatggatgta
     3061 cttgcagaaa tattaaaagg cgggtttgct aaagtgaaag aaagtggagc acttttggtt
     3121 ggagggcata ctgtagatga taaagaacct aaatatggtc tttcagtttc tggaattgta
     3181 aatccaaata aagttttatc aaatgctact gcaaagcctg gtgataagtt aattataaca
     3241 aaaccaattg gagtgggtgt attaaacaca gccatgaaag aaggtatggt agaacaacat
     3301 atagcagata aagtaataga aataatgata catttaaata aatatgcagc aatgagtttt
     3361 gataaatttg atgtaaattc agttacagat ataactggtt ttggtctact tggtcatact
     3421 ttagaaatgg ccaaagcttc cgaagtaagt attgaaattg aatcaaaaca tgtgccaatt
     3481 attgaaggta caatagaaat ggcacaaatg ggaattatac ctgctggtat gtataaaaat
     3541 atgcattatg tatctaaaga tgtagagatt gtaggaaatg tagaagttgc agttcaagat
     3601 attttatacg acccacaaac atcaggaggg ctgttaattt cagtaaaaga agaacttgca
     3661 gaggagcttg taaaagatat gaaattaaat ggagcaatag aagctaaaat tataggttct
     3721 gtagttccaa aaggggaaaa atatattaca gttttataaa atattataga gaaagagtga
     3781 ttattttgag caaaagagaa ttgtttgcaa tgttgccttc agttgatgaa gtattaagtg
     3841 ataatagaat tgtagaaata ataaatgaat atcctagaag tttagtttta gaatctgtga
     3901 gagaagtaat agatttaaaa agacaattta tattaagatt aaaagaagat atatcaaatt
     3961 ctgtaacaat agagtttggt gaaataatag aatctgcaat agagagagtg aagttaaatt
     4021 actcattatc tttaaaaaaa gttataaatg caactggtac agttattcat acaaatttag
     4081 ggaggtcttt acttagtgaa gatataaaag atgaattatg gtgtgctgct tcaaggtatt
     4141 caaacttaga atacgattta gataatggag aaagaggttc aaggtactct catttaacta
     4201 gtacaataaa aagacttaca ggagcagaag atgtactagt tgtaaataat aatgcagcag
     4261 cagtacttct tgtacttagc acaatggcta aaggaggaga agcaattgta tctcgtggag
     4321 aattagttga agtaggtggc tcatttagga ttccaagtat aatggctctt agtggtgcag
     4381 aattagttga agttggttca actaataaaa ctcacctgaa agattacaaa gaggccatta
     4441 cagaagatac aaatgtgctg atgaaggttc atacaagtaa ctatagaatc atgggattca
     4501 cagaaagtgt ttctatagaa gagttagtta atttaggtaa aaaatataaa ttgcctgtaa
     4561 tagaagactt aggaagtgga gtatttatag atttatcaaa atatggttta tcttatgaac
     4621 caactgtatt agattctatt cgacaaggtg cagatgtggt aacttttagt ggagataaga
     4681 tgcttggagg tccacaagca ggtattatag ttggaaaaaa agaatatata gaaaaaatga
     4741 agaaaaatca acttactaga gcccttagag tcgataaact tacaatatgt gctcttgaag
     4801 ctacattgag aatgtattta gatgagacaa aagctataga aaatatacct actttaaaaa
     4861 tgttgacgta taaaattgaa gagttagaag taaaagcaaa taaattattt gaaaaaataa
     4921 ctgctttaaa cttaaatgca aacataaata tagaagatgg attttcacaa gtgggaggag
     4981 ggtctatgcc tcttgaaact ataagtacaa aggtaatagc aataactcct gaacatatga
     5041 atgtttcatc tttagaaaag aaactaagac ttagtgaagc tcatataata gccagagtgt
     5101 atgataataa atatgtacta gatgtaagaa ctatatttga tgatgaattt gatgtaatag
     5161 ttgatgaatt gagaaaagca tttaattaaa taaatttgag ttaataaata ttaaatttag
     5221 aagtataagt atgaagtttt gattaaaaaa tagctacaca cacttgtgac tttagtcata
     5281 ggaggtttag agggggcaaa aaatgaaaaa tgtagtaatt ggaacagcag gtcatattga
     5341 ccatggaaaa actactctta taaaagcatt gactggaaga gagactgata cattagatga
     5401 agaaaaaaag agaggtattt caataaattt aggatttact tattttgatt taccaaacaa
     5461 tagaagagct ggaattgttg atgtaccagg acacgaaaaa tttataaaaa acatgttagc
     5521 tggagcatca ggaattgata tagttttact tgttgtagca gcagatgaag gggttatgcc
     5581 acagacagtt gaacatttag atattttaag ttttttaaat atcaaaaatg gaatagtagt
     5641 tctaactaaa tctgatactg tagatgatga atttagagag ctagtaaaag aagatatttg
     5701 tgaaaaaata aaaggaactt ttcttgaaga tgctgaaata attgaagttg attctatatc
     5761 caaaagaggt atagacaccc ttattgaaaa aatagataaa atgagtgatg atatagaaga
     5821 taaaaatgaa agctctccag caagacttaa tatagacaga gtattttcaa taaaaggatt
     5881 tgggactgta ataacaggta ctttaataga aggaaagata agtatagaag atgatttggt
     5941 tatatatcca caggtattaa aaacaaaaat aagaagcata caagttcatg gagaaaataa
     6001 agatacagct tatgcaggtc aaagaacagc aatcaatata tcaaatgtaa aagtggatga
     6061 tataaaaaga ggggatgttt tagctgcacc aaattcatta gaggaatcaa tgatgttaga
     6121 tgtaaaatta tcattggtaa atcatttaga taaaggatta aaacactggg atagattaag
     6181 attgtaccat ggaaccagag agatactttg tagagcagtt ccactagata aagaattaat
     6241 tgaaaatgga gaaagtggct atgttcagtt gagacttgaa gaaagcatag tatctaagaa
     6301 aggcgataca tttgtagtga gacgttattc tccaatggaa actataggcg gaggtgtaat
     6361 aattgaccca tctcctaaaa aacataagaa atttgatgaa aaagttatag aagcattaaa
     6421 aataaaagaa aaaggtgaac taaaagatat aatagaagag tacttaaaaa ggaatctaaa
     6481 aaattatcca aatataaaag aaataatgag ctatagtggt gctcatgaag aagatgtaaa
     6541 aaaagcgctt gaaacactta tatcaggaga taaagtattt attataggaa atatgtatat
     6601 gcatgtaaat caatacaata aattaaaaga aaatacaata aagcttttaa gtgagtacca
     6661 taagaaatat agacttagaa aagggatgtt aaaagaagaa gtaaggtcta agatagagag
     6721 taattttaag actagggaga tggatatttt attagaaaaa ttatctacag aaaatgctat
     6781 aaaaatagaa aataatatag tatctttatt agattttgag gttattttaa atgagaagca
     6841 aaaagaaata gcaaaaaaaa tagaaaaaag attaaaatca tgtggagttt cttctatact
     6901 gacaatagat gaagtttctg aaggaaatca taactatgct gaagtattgg agtcaatgat
     6961 aggtaataaa gtagagaaat tagatgattt gtatataatg gacaaagata tttatgaaaa
     7021 tgcaaagaat actttgataa attatataaa agaaaataaa gaaataacat taggagaata
     7081 cagagatttg attgattcta gcagaaaaaa ttgcatgatt atattggaaa acttcgatag
     7141 aaacaaaata actaagagag tagaaaacaa aagaattttg ttttagcaga aaatgtctgt
     7201 ttttgcttta aggtataaag aaggaattat aatgtcgagt atcgtataat taattagtat
     7261 aaaatattaa ttaagaggaa gtgtaaagta ttgaagagca taatacctga tgtaaaacca
     7321 gatataaaag aaagagaaga catgagcctt ttatttataa taatgggctc agtactttta
     7381 ttatttatta taaaagatac agataaatat gaaactttat tacataccat atatactata
     7441 ttcttagtag ctacaggagt aattgtattt aatactacaa aatttaaagt agattcattt
     7501 tctacatttt taggattaat ttttatagct actggagcat tggagtgtat atatttattc
     7561 aattcattag aaattaaaac tcagtttgtg agagaactta acattacaat atcagcaata
     7621 acagatttat ttcctatatt gggagtatac ttaagtttca aatttgtaaa agataataaa
     7681 caaatttatt caagtataat tttatttata gtaactgtta cattgacaat aatatcttta
     7741 ttcataatat ctggaatttg tgaatattta ggaaatggta cttcacaata tgctttagaa
     7801 gttataatat ctatatttat aataattatt tctattgtta gtggaattga attaaactta
     7861 agttcaagtg aaggtaaatg ggaatataat gaaaaaaaga tttttaacag aataatagta
     7921 ataataatct tatcaagagt tccaaatcta ttacatatag ttattgatga taggaatata
     7981 gagagaatat tatcacatat aataataaat gtagctatat attatttata taattacata
     8041 gtatctaaga atattaagaa aacagcatta gaattacatg acataaatga agagttaaca
     8101 ctaaaaacgg aaagtttgaa agaaaaaaac aaaaagttaa tttatgagac agaaaagata
     8161 gaggaactta agggaatact tataaaaaga gaatctagac tgcaatctac attagatgta
     8221 gcagtaaata gtatagttgt atttagtaaa gatggagaaa ttacatatgc aaataaaagc
     8281 tttagaaata cttttggaga ctataaagaa caagataaat tgactgataa aataaaaaac
     8341 ttcaatgatt tgatagaaag cattaattat gtgtttgtct atgagaagaa tgtagaaaaa
     8401 cttattagta caagcgataa taaagtctat caagctatat ttgcaccttt aattattgct
     8461 tcacaaacag aaggagtatt gtgtgttctg gaagataaga ctaagaaaaa agagtatgaa
     8521 cgcaaactta ttgaagcaaa taagagaagt agagagtttt tagaaagtat tggagatggc
     8581 atagtagtgc ttgaaggtaa taataaaata tatgttaata atgcatgtag ggaaattttt
     8641 aaaaataatt tagaaagtat tgatttttca ttagtatgta aaagtgaaga aagtatagaa
     8701 aaaagatatg taatagatgg tgaagtaaag tatgtagaga tgagtttttc tcaatatact
     8761 aatgctggta ctgataaaac tattattgta atacgtgata caacctctcg aaaaatatcg
     8821 caaataaaac ttgaggaaag tcaatcatca tattcaagat ttatagatat attacctgat
     8881 ggcatatgct tattaaaaga agatttaagt ataaactatg caaataagtc gtttttagat
     8941 atgctagctt ttacaaacat agatgatata aaagattcta atattaagct attaatgaat
     9001 gcgaatactg aagaaaaaat gaaatttact gataatatgg ctaaagtttt aaatgaaaat
     9061 agaagtatac ttttactaga gtatgaattg ataaatagtt ataatgatat agtagaagta
     9121 gaattaagtg cattaccttt tgctatatac aatactagat atataatgct tattataaaa
     9181 gacttagtac ataagaaata ttccgagcaa gcggaaaaag aactacttga aagatttaaa
     9241 acagataaaa tcaaaacgga gttttttgca aatatgtctc acgagttaaa aactccacta
     9301 aatgttatat ctagttcgaa tcaactagta gattctttct atagaagtga aaagataaaa
     9361 gattacaata ataatattaa atctcatgtg gatttagtta gacaaagttc ttataggctt
     9421 caaagattaa taaataatat tatagattta acaaagatgg agtctggatt ctatacgtta
     9481 aaacttgcta aatacaatat tgtatctgta atagaagact tatttatgaa tatagaagag
     9541 tacgcactta gaaaagatat aaaaattctt tttgatacag aacttgaaga aattaatatt
     9601 tatatagaca aggttgaaat tgagagaatt atgttgaatc tattatcaaa ctgtattaag
     9661 tttactgata atggaggctg gatatatgta agtattcatt ataaaataga taaagtaatc
     9721 ataagtgtaa aagatactgg agttggaata ccacaagata aattagaact gatttttgaa
     9781 gaattttcac aagttgataa gactttatct agaaatactg aaggaagtgg aatagggctt
     9841 gctatagtta agaatctagt aagtcttcat ggtggagata tagaggtaat aagtgaagtg
     9901 aacaaaggca cagagttctt aatttcactt ccaatgaagg gatttagtag tgaacattac
     9961 acagaagata agagaatata taatattcaa gaaaaaataa aaatagaatt ttctgatata
    10021 tactattaga agtgattatg agtaaaaata aaataaaaat actatctatt taaatattta
    10081 agctataaga aataggctat cataagataa attattatga tagcttattt ttagttaggc
    10141 tttatatcta tatgtgagaa catataatct ctaaattacc ttcaaaacca aattctccaa
    10201 agttgtttgg tagtataaaa tgcataccct tttttaaatt gtattctaca gcattgtgta
    10261 taagttttcc atttccatcc aatacactgt ataaagaaaa aggtgtcttg tgtgtaaaag
    10321 tacactttcc aaaaatatct aatttataaa cgctaaaaaa ttcatttgat acaaatgttg
    10381 tgcatctaaa gtctgatgtt gacacaattt tatagtcagt atcaaaattt atatgaggaa
    10441 cattggtaac atctattgat ttttgaacgt gaagttcacg tttattacct aaattgtcag
    10501 ttctatcata atcataaact ctataagtag tatctgaatt ttgttgagtt tctaaaatta
    10561 atgttccttt acatatagca tgtatagtac cacttggaac atagaaaaag tctccctttt
    10621 ttatattaac ctttctaagt agtttgtccc attcattgtt atttaccata tccacaaatt
    10681 ctttatgaga ttttgcatta tgacctatta taatttctgc atcatcagaa caatctatta
    10741 cataccaaca ctctgtctta cctaactctc cattttcatt ttttttagca tattcatcat
    10801 ttggatgaac ttgaactgat aaattatcat ttgcatccaa tatttttgta agtaaaggaa
    10861 atttatctcc aggtgtgttt ccaaataatt ctctattttt atcccacaat tcagatagtt
    10921 ttttaccttt atagattcca ttttctatta agcaatctcc atttttatga gaacttatag
    10981 cccaacattc acctgttgtt ggcgaatcta tttcataatt aaatttatct ttaagtgcag
    11041 taccacccca tattctatcc ataaaaatag gttttaaaaa taatggttcc ataatcctgt
    11101 tcctcctatg atattaaatt tatcctacaa ataattatat ataaatacat tataaaatca
    11161 atagtaaaaa agttttgtcc cttgaaatga cataaagtat aaggagttat taaataagat
    11221 aaactatgat atataatata aagttctaaa ttggagtgat aattatggaa ttgtttaagg
    11281 aagaaatcaa aaaatacgaa aaagaatttt tgaaattatt ggaagaatgg gtgagcatac
    11341 cttcatttta tgatagaaaa actgtatcta aagatatgcc ttttggaaaa ggggtatatg
    11401 atgcattaaa ctggtttgaa aatctaggta gagaaaacaa tttcaaagtg aaaaatatag
    11461 ataatcatgc tgttcaaatt gaatatggaa atggcaaaga gtatgtagat atatttggac
    11521 attgtgatgt tgtaaatcca ggtgaaggat gggatagtga accttttaaa ttaaatatta
    11581 taggtgataa attagttgct agaggtgtat ctgataataa aggacctatg atagtgaatt
    11641 ttttagcact aaaaatgata aaggatttag atattaattt aaaaaggaag gttagattaa
    11701 tagctggagg aaatgaagag agtggattta agtgtataaa gcattattat agcaaagagc
    11761 catatggggt atgtggattt actccagatg ctaaatttcc tgtattaaat ggggaaaaag
    11821 gtggagcaat aataaagttg ctttcaaata tagacgataa atctttatac ataagtggtg
    11881 gaatagagtt taatacaata ccagataaag tttatataaa gaatatagaa aaattgggta
    11941 aagataatat atgttttgat attaacaaga tatcgataag ttatgataat gacaattata
    12001 ttgtgcatgg aaaaggtgga cattcatcta aacccgaaaa atcaataaat cctatattag
    12061 ctacaattaa acttttgtca gaaaatattg atgaaaaatg gacaaaagat ttgtataagt
    12121 tgataaatca agataatata aatggaaatt tatttggttt aaatattgaa ggaaaatgtg
    12181 ggattttatc aatggtgcca acaataataa atatagtaga cggaaaatta gaagtagttt
    12241 taagcgctag atatccagaa atattaagca ttgaagagat aatgaaaaaa tttaatttgt
    12301 atatggagaa aaataatatt aataaatttg agcttattgg ggaaaattta aagcaagcaa
    12361 attatataga taaaaattca aaactcgtaa aaagtttgca tgatatatat ataaagtatt
    12421 ctggagattt aaaaaatgat gttagagtaa ctagtgcagg aagttatgct tctgaaatga
    12481 ataattcagt aatatttggt tgtgaatttc ctgatggtag ctttggtaat gtccatggtg
    12541 cgaatgaatt tgctagctta gatagattta taactgcaat aggtatatat gcagaggcaa
    12601 taattacatt atgcaacaaa atataaatac aaaatgtccc ttatatagac atattatata
    12661 tacaattaaa attttacttg atatataatt gaaatcaaag agaaggtgat acaatgataa
    12721 ctaagaaaca tgcaataata gtaaagagtt taagcaataa agatggatat atgacatcaa
    12781 atgaattggc tatcaaattg gatgtgtcta ctaaaactat taaaagatat atagcagatt
    12841 taaatagtgt tttaagcaag tatgatttgg taatagattc ttctagaggt ataggatata
    12901 agttaagcgg ttctaaaaac aatatagcca gagctatcaa agaagcaaat aaatatattg
    12961 atggtttttt agatgattct gaagagtcaa gaatgtcaaa tataatatgc atgcttatta
    13021 atagaaatta tatgagtata gaagcaatgg cagaagaatt aaatctaagt atagccgcta
    13081 taaataaatt gtctagtaag cttaaaagaa aacttgaaaa gtatgactta gttataaaat
    13141 ctaaacctta ctatggaagc tatatacatg gtgaagaaat taatataagg caattaatta
    13201 ctgactatgc aataaaatta gatgaaaaaa gtaaagtgaa ggtgttttta gatgacatta
    13261 gtgaaaacga tatatactgt atagaaagta ttttagaaaa acacttaaga gaaaaagata
    13321 caataatttc agataaagat tttaatcttt tgctttcaaa aataatcgtt tctgtattta
    13381 ggagtaagag aggtcatagt aacaatataa acttaatgga tacaagttat agatttcata
    13441 actactactt tatagaaagt ctaatgaaag aaatatctga taaaattgga tttaaactta
    13501 ttgaagatga agtaatttat atttcaaatt attctggtgt aatagcctgt aaaggtacac
    13561 aaggaataaa aaacacaagt gagcttgagg agcgaataaa tagtgttatg agcagtgctc
    13621 ttcaagatat attccttatt tcgggcagtg attatacaaa agatgatgag tttatggttg
    13681 caatatctga ccatataaaa agatttttaa atagggctag agctaatgta aaatcaaata
    13741 atcctttact tcatcaaata aaagagaagt ttcctatagc ttttaattta gccgtgtttt
    13801 tatcaaataa actagaaact gagtttaatt taaaacttga tgaagatgag cttggatata
    13861 tagctattca ctttgctgct tcaaatgaaa gaatgaaaaa aaatactagt aagaaaattt
    13921 gtatagtttg tcattatggt ataggaacag gacaacttat ttctgaaaag ctaaaacaga
    13981 atataagtga tttaagtgtt gtaggtgttt atccagttag atatctcgat atggctataa
    14041 gtcaagatgt cgatttaata gtatctactg tcgaattaaa aggatatgaa aaacctgtct
    14101 tatatataga aaatatattt gatgatagct taattgaaaa cgtaaacaaa gctttttatg
    14161 aaaaggaaga aagaagaaag ataataagta acatgtttga tgaaaaagct tttttcaata
    14221 taaaggctaa tactaaagaa gaggtcatac tttcactttc aaataaacta aaagaaagag
    14281 actttataga ggaaagttct ataaaaagca taatagatag agaaaatatt tcatcaactg
    14341 aaataggaaa tctagtagca atacctcaca caatagtgaa gggagataaa aaatctataa
    14401 taggagttgg aatacttgaa aatccaataa tttgggataa gcaagaggtt cagctagtat
    14461 ttatggtatt ttttaatact aaagaaaagc ataatttctc gatatttaaa tacctttata
    14521 attttataaa agatgaagga ggagtaagag ggattattaa aatatgtgac tttaataaat
    14581 taatggcact gataggtaat taaggaggaa attaataatg ggaacaaaca tatttaacaa
    14641 agaatatgta tttttaaatg ttgatgctaa gtcaaaggtt gaagttttaa aatttatatc
    14701 aaaaaaagct aaagaattaa atttggcaga agatgaaagc ttagtatatg aaggtttaat
    14761 gtctagagaa gaacaattta ctacaaattt aggagaatct atagcaattc ctcatactaa
    14821 aaatgatgca attgaaaatc cagcagtagt agtgttgaag tttaatgaag atgttgtttg
    14881 gaatgaaggt gaggataagg ttaaattagc aataagctta cttatgccag gaaaaagtaa
    14941 agaaaatatt catcttaaat tgttatcatc tctttctaga aaattaataa ataaagactt
    15001 taaagattct cttttaaaga gtgataatgt tgaagaaata tctaacttaa taaatgaagc
    15061 tttaggttta taattaaaca ctaaggttat aaaataaaaa ataattaact aaaaatagga
    15121 ggaatttaaa atgaataaaa aattagtagc attatgtgct tgcccaatgg gattagctca
    15181 cactttcatg gcagcagaag caatagagca agcagcaaag gctttaggtt atgaagcaaa
    15241 agttgaaact caaggtgcag atggtgtaca aaatgaatta acaagagatg atatattagg
    15301 agcaactatg ataatacatg cagtagcaat aactccagaa ggtatggaaa gatttgatgg
    15361 gtgtgaagtt tacgaggttg agttacaaga agctataaaa aatgcagagg gtgtcataaa
    15421 agaaatagaa gaagatttag gaatataata aatttattgt ggaggaaata gaatggcaat
    15481 taagaaaaaa gttataaaca gttcaggtgc ttctacaaca ggaggaaata atgtaggaaa
    15541 atctactcca tctagtccaa ctcaatcaaa gggaaatgga aaatggaaag aaataagtaa
    15601 acatataatg acaggtatat catatatgat accagtttta gtaatgggtg gacttatagg
    15661 agctttatct caactaatac catatgctat attaggactt gacccatctg taggtatagt
    15721 tgatgctatg aactcaggag aatttacagg gttcaagctt agtcttttaa atatagcaca
    15781 attaatgtca aatttcggat ttactttgtt tggatttgca ataccactat ttgcagcatt
    15841 ttgtgcaaac tctataggtg gaaaaacagc cttaattgca ggatttatag gtggatatat
    15901 agctaataaa cctgtaggtg taccacaatt tgttgatgga caatggactg aagttgttcc
    15961 agttgcatca ggatttttag gcgcaatatt aatagcattc ataataggat attttgtaaa
    16021 atggttaaat aaatctataa aagtttctca taactggtta gcttttaaaa caacattttt
    16081 aataccacta atagcgtcat tagcttgtat ggtattgatg atatttataa taactccatt
    16141 tggtggacta attaatgaaa gtatgaaaaa cttcttaaca gcagcaggag cagcaggaga
    16201 atatgtatat gcaacagctt tggcagcagc tacagcattt gacttaggag gaccaataaa
    16261 taaagcagca ggattcgttg cacttggttt aactacagag aatgtacttc caataacagc
    16321 aagaacaata gctatagttg ttcctccaat tggattagga ttaacaacat tattagataa
    16381 aaaactagta ggaagaagag tatatgatag acaattctat caagcaggaa aaacttctat
    16441 attcttatca tttatgggta tatctgaagg agcaatacca tttgcacttg aaagaccagg
    16501 ctttgttata cctttaaaca tagtaggaag tgtaatagga gctattacag gtataattct
    16561 aggagcaatt caatggttcc cagagtcagc agtatgggca tggcctctag tagacaactt
    16621 atttggatat ataataggta tagcagttgg tgctatattt atagcagtag gaaatatatt
    16681 ctatagaaat aaattaataa aagatggtaa acttgttgta gattatatcg actaatattt
    16741 aatttttact atctataaat aaccttggct ggtaatatgg ttttaatcaa tattaccagc
    16801 cttacctata tgattaatta gaggcggtgg agataagata tggataagat agaaaaagta
    16861 agagagtatt ttagagaata tgatatagat ggatttctta tcaatagtcc tacaaataag
    16921 ttttatgttg gaaatttatt tagttcttca ggttatgttt ttataacgaa agaagcacaa
    16981 tatataatag tagattttag atattttgaa gaaattaaaa gaaaatcgag cttgtttaat
    17041 gtagtattaa tggacaaaac tagaactcat tttgatataa ttaatgatat ttgtagagaa
    17101 cagaatataa aggaaattgg atttgaggga aatgaagtat cttttgattt atatagaagt
    17161 atgagtaata agttaagtgc aaccttaaaa tcagttgatt tatctacatt aagggaaaca
    17221 aaaaatgaag acgaaataaa atatataaaa aaagcttgtg aaatagttga tgctacattt
    17281 tatcatataa tagactttat aaaggttggt atgactgaaa agcaagttga aaatgaaatt
    17341 gttagagtta taaaagattt aggtggtcaa aaagaatctt tcgatacaat agttgcatct
    17401 gggcttagag gagcattgcc tcatggaaaa gcaagtgaaa aagttataga gtatggagat
    17461 tttgttactt ttgactttgg tgctaagtac aataattatt gttcagatat tactagaacc
    17521 atttgtatgg gtactataaa taaagagtta gaagaaatat ataatatagt aagaaaagct
    17581 aatgaagagt gtataagggt tttaagacca ggaatgacta ctggagagat agataaagtt
    17641 gcaagagata taattggttc atatggatat gccaataatt ttggtcataa tctgggtcat
    17701 ggtgtaggaa ttatggttca tgaatatcct gcattagctc ctgaatcaaa tgaagtatta
    17761 aaagaaggaa tgattgtaac tatagagcct ggtatatatg ttccaagtct tggaggcgta
    17821 agaatagaag atgatgtact tataacaaaa gatggatgta tgagattgac tacatctact
    17881 aaggatttaa tagttgtcag ttaaaaataa attaggtaaa tattttataa caataagaaa
    17941 agaagaggta aatttaaatg tataattttg ataataaacc agatagagta agtgagaagt
    18001 gtagaaaatg ggatttaaat attataagag ataaatttgg agatattaga gaagattttg
    18061 taccaatgtg gattgctgat atggatttta aaataccaac agaaatagaa aacaaattta
    18121 ttgaagctgt aagaagaggt gtatttggat atacatactg ttatgatgaa ttttatgatt
    18181 cagttattgg gtggcaaaaa aatatgcatg aggtagatgt agaaaaggaa tggattacat
    18241 taacttatgg aactgtatcg acacttcatt atgtagtgca agctttttgt aaaaaaggcg
    18301 atagcataat attaaacaca ccagtttatg acccttttga atcatcagca aaaaaacagg
    18361 gtgtaaatgt aatttgtaat acattagatg ttgtaaatga tagatattat ataaattttg
    18421 ataaattaga agcacaaatt aaggaaaata agcctaaatt aatgatgttt tgtacaccac
    18481 ataatccatc tggaaggata tggacgattg aagaaatgac aaaagtagca actatatgta
    18541 aagaaaataa tgttattttg gttgcagatg aagtacatgc agaacatatt cattatggta
    18601 aatttaattc aatacttaag attgaaaaag agcttttaga aaatgttatt ctattgacat
    18661 caccaaataa aggatttaat cttggtggat taaagacctc ttattcaata gttataaata
    18721 agaatataag agacaaattt agaaataaac taaagcaaaa ttctataact tctccaaatg
    18781 tgtttggaat aatagggttg ataactgctt ataatgaatg tcatgagtgg ttaaatggtg
    18841 taaatgaata tataaagtca aattatgaac ttttagaaac ttgggtaaat aaatatagta
    18901 agataaaatt gatgaaaatg gaatcatctt acttagcttg gatggatata agtggattag
    18961 gcataagtgc aagtgagttt acagataggt tggctataga tacaggagta ttattagaag
    19021 atggaagtca ttttgtacaa gatggtgata agtatgttag aataaattta ggaactcaaa
    19081 aagaaaatgt aattgaagct ttaaatagaa tggatttgtt tttaaaatct ttataaaaat
    19141 ttggttaaat tatttattga aaatataaaa aagtagctta ttcaattata aaaataaata
    19201 tatttaatgg taggcatttc ttatgaaatg tctattttta tatgattatt gtaaagtttc
    19261 ctttacaata aaatagtaat atgatatatt atatgtgtaa aggaaacttt acaatgaagg
    19321 aggagatatt tttgaaaaat tgtgtagaag ctttgagaaa gaaaaaaggt cttaatcaag
    19381 aggactttgc aaaaattctt aaggtttcaa ggcaaacgat tagttctatt gaaaatggaa
    19441 aatataatcc atctttagaa cttgcatttc agatatctga tttttttgaa atgtcgattg
    19501 aagaaatctt tttatggaag gagatataat ttatggaaaa aaggaattta agaataggaa
    19561 tagtatatgt agttttagga gttactttct tgttttcttg tttaatgact aaggataagt
    19621 taagttcttt gcttgttggt ttagcagcag gatttggatt taatggaatt tctataattt
    19681 atcgatattt ttactggaat aagcataagg aagaatatag agaaaagcta gaagaagaaa
    19741 aaataaacct tcaggatgaa aggaatgtaa tgtatagaga taaagcagga cgatatgctt
    19801 atattgtgtg tatgattata attcctatat ctgcttttgt tttcgctgta ctaaacgcct
    19861 tagatatata caactcatta gtaatcatta tatatctatc tgttttatgg attgttttgt
    19921 atgttgtagg agttatttac tatcgaaagt taaaaaataa tgaatagtat ttatataaat
    19981 ttaagctatt aatgtggtat atacataagt acaatttgtt ttagactact taagtatata
    20041 ccacatttta tataaatttt aaatttgcat tagttattta ataactattt aaattcatat
    20101 gtattttgta tttataatag gtaaagttat tatttaaact tattatttat ttaatttttc
    20161 aatagaaaag gctttatctg taagtttaaa attatctttt atacccttag ttaagtatac
    20221 tttcttatcc ttagttatga atatagcatc tacattatca attctattaa ttaaatccat
    20281 acctttttca agtccaagtc caaatgtaga agtggataag gcatcacaat taatagattt
    20341 atcagagatt attgtaacac tacttaaatt gttttcaaaa ggataccctg taaatggatt
    20401 taacatatga tgatatattt ttccgtcttt ttcgataaat ctttcataaa ttccagaagt
    20461 aacaacagat ttatttgttg tttctatgtt tcctatagat tcaccatttt tactagttgg
    20521 gtcttgaata cctattttaa aaggtttatc atttttactg tcttctaaag tgaatatatt
    20581 tcctcctaag tttactaaac ctttttttat atcctctgat tttaaatagg atacaatttt
    20641 atcagcagca tatcccttag ctatggcacc taaatcaatt ttcatatttt ctttgtttaa
    20701 ttttatagat ttattttttt catccagtat gatgttctta taatcaataa gaggcagaag
    20761 tttttgtatc tcagaatcac ttggaacttt agctttatcc gttccaatcg cccataaatt
    20821 tgataatgga ccaattgtta tatcaaaata tccatctgat aatttggaat attgtatagc
    20881 ttcttttacg acgaaaaatg tatcatcgga aactttgaca aatttcttac cagcattatc
    20941 atttatttta gaaacatcac ttcctggtat atgagtgctc attttgttgt caatatatct
    21001 taaaattgaa tcacattcat ttaagatttt atcacttttg gattctttta cattaaatac
    21061 agtaacttcg tttactgtac caaggtagta gctagtctta ctatatttag tattctggcc
    21121 tgaactccta aaaaatgaaa ataaaattaa tgctaaaatc aatatcacaa aaataaatgt
    21181 gatttttttc ttattcatgg tatattcctc ctatgaaatt gtgttattat tttattataa
    21241 cataatttca taggaggaca aaaaatgaag aaaaaagaca ttcttcttat tttaggcatt
    21301 ttggttgtta ttacagcatg ttatgggata ataaatgtta taaattctaa aaatgctgga
    21361 aatattgaga tttatgtaga taataaattg tataaaactg tttcaataaa tgcaaaagaa
    21421 gaatttaaaa tagagaatag aggggggtat aacatagtaa agattcatga taaaggggtt
    21481 gaaatagtag atgcttcatg tcctgataag gtttgtgtac atactggatt tataaacaag
    21541 ccaagtcaaa gtatagtttg tatacctaat agagttagca taaaaataaa tacaaatgaa
    21601 aagaatgata atcaagaaga tataatttct aaataacata ataaaaataa ttgaaaggaa
    21661 ttggtgatag ttatggttaa cttaggaaac gattgggatg aattattgaa agaagaattt
    21721 gaaaaagatt actacttaaa tttaagaaaa tttcttatag aagagtataa aacacgtcaa
    21781 atttttccaa atatgcataa tatatatgaa gctttaaagc acacttcata caaagacaca
    21841 aaagttttaa tattaggaca agacccttat catggagata atcaagctca tggtttagct
    21901 ttttcagttc aaccacaagt gaaaacccca ccatctctat taaatatgta caaagaatta
    21961 aaagatgatt tagggtgttt tatacctaac aatggatatt taatgccttg ggcagaccaa
    22021 ggagtgttac ttttaaatac tgctcttact gttagagcgc atgaagctaa ttctcataag
    22081 aacaaaggat gggaaatttt cactgataga gtaatatcta ttttaagtga gcgtgaagac
    22141 ccagttattt ttgtattatg gggaagtaat gcacgtaaaa aagtggaatt gattgataca
    22201 agtaaacatt atattttaga agcacctcat ccaagcccat tgtcagcaag taaaggtttt
    22261 tttggatgta aacacttctc taagataaat gaaattttga aaaagctagg aaaagaacct
    22321 attaattggc agatagaaaa catataaaag taaaaggtaa caaaatgata acaaaacaca
    22381 ataaacaatg acattgttgt aactaataga aatatgctta aatagttgaa aaaactatat
    22441 atgcatattt atattttttt gtcaagttga caactcttga aaaaatagtt acaatttagt
    22501 tacacaaaaa acacaaataa aaaaagaaac ttacaaagca gaattttatg aagcaaaata
    22561 tatagtgtaa aaaatcttag ggaggaaatt ttatatgaat tttaaaaaat tgagtaatgt
    22621 taaagtctcg gtaatggcag ttgttttatc agttggaata ttatcgggat actctgcgct
    22681 taataaacaa gtaacattag tagtaagggg agaagaaaga actatatcaa cattcagttc
    22741 taatgtagga gaccttttag aatctcagaa cattagctat gatgcaaatg atatagtaac
    22801 tttagataaa aatgcaaagt tatctaatgg agataaaata gaagtaattg atgtaaagga
    22861 aaaaacagtt gtagaaacta aagacattcc atttgaagtt acagttgttg aagatggctc
    22921 tttattaaag ggtgattcta aggttaaaga agaaggaaag tctggtaaaa gtgaattaat
    22981 atataaagaa acttatcaca atggaaagaa agtagaaaaa gaatttgtga aaaaggttgt
    23041 taaagctgag ccagtaaata aggttgtaag taaagggaca aaggtagaaa tgcaagtagc
    23101 ctcatcaagg ggagaaagct caagaagaat ggcttcatca tcatctagta gcagtagtag
    23161 taacaatggt aaaaatatga gagtggtagc aactgcatat actggtcaca gtataactgc
    23221 aacaggaaca aaacctaagt ggggaacaat cgctgtagac cctaaggtta taccatatgg
    23281 aactaaagtt tatatacctc aatttgatat ggtgtttact gcagaagact gtggtggagc
    23341 gataaaagga aataaaattg atatctacat gaatgattca aaaacagttt ataactgggg
    23401 aagaaaaact atagatatac gtatattaaa atagttaaat aatttatatt tacactggaa
    23461 attatatttt gattatatag agaagaaatt ctttatagat tcttaaaata taattttcag
    23521 ttttttattt tatatataat aaaaaaggta aattttaacc atgtatagat aaaacctatt
    23581 taaattataa tttactatca gataaatcta taaaaattgt tgcaaagagt caaaatatat
    23641 gatattatag atttcgttga gaaggatttc attatgggag tggatgggtg ccggtgtgcc
    23701 ctctagtctt caaaactagt atgaggggtt aagagcctct taggtgggtt cgattcccac
    23761 gcattcccgc caatatgtaa aaggtatctt ttaattaaaa gatacctttt taaatttatt
    23821 ttaagatagt ttatttttaa taatatataa tattttgtat tatataatgt aaattttcta
    23881 atactattat atatttagat aaaaatctgg gagtgtggaa agatggaaaa taattttacg
    23941 acgagaacta gttttctagt tggagatgat ggaatagaaa aacttaataa ttcaaacata
    24001 atagtatttg gagttggagg agttggtagt tttactgttg aagctttagc aagagctgga
    24061 gtaggtaata ttaccattgt ggattttgac gatgtagata taacaaatat aaatagacaa
    24121 ataccagcac tacattcaac tgtaggaagg tataaagttg atgttatgga agaaagaata
    24181 ttagatataa atcctaatat caatataaaa aaaataagaa gtctttacaa tcaagatact
    24241 agtgatgaaa tactgactga aagatatgat tatgttgtgg atgcgataga catggtaagt
    24301 tccaaaatac atctaattga aacttgtgag aaaaaaggat taaaaataat aagttctatg
    24361 ggtatgggaa ataaattaga cccaaccaaa atagtcgtta cagatataca caaaacaagc
    24421 acttgtcctc tagctaaagt tatgaggaaa gaacttaggg atagaggtat caaaaagtta
    24481 aaagtagtat attctactga acaaccaata gaacttaaga agaaagtaat gaatggtaga
    24541 aaggtaacac ctggtagtgt atcattcgta ccatctgtag gaggtttaat aatcgcatct
    24601 gtaataataa atgagctatt aggacaataa gttttaaata ttttaattta taaattttat
    24661 atataaactt gaaggctaga agaattaata taaaatagtt ttatattaat tcttttagcc
    24721 taattatttt acattacctt attttatgta gttgtagttt tatttttttg attatgtatc
    24781 tacttcataa ttatattttg taaatataat ttctccatca ctataaaaaa caatatctcc
    24841 tattctgtct gttctataaa ttgatacatg gctttgtttt agattatcaa taacctcttt
    24901 atgtggatgt ccatattgat tcttatatcc acatgatatt gcagctatgt ctggattaat
    24961 tttttttata aattctaaag atgatgaaga attacttcca tggtgaccta tttttataaa
    25021 attaatattg tttaattcaa aagaacgtaa aatttctttt tcattttctt cttctgcatc
    25081 acccataaat aaaaaagagt tattgttaaa agttaatttg aaaactatag aatttaaatt
    25141 agattcttct tgtatatatg atggacttaa tacatatata tttatattgt tatctatgtt
    25201 taaaacatca tctttgtaga gatactgaat agctaagttt ttatccgtac aagaatttat
    25261 tagattttga taagattcac tattagttga ttgttcaggc atatatatgg agtttacatt
    25321 aaattttttt ataacattat caagacttcc tatatggtct gaatctggat gtgttgctat
    25381 tataatatca atagttttta ttcttttttg tctaagataa ctattaatta tatttttact
    25441 atattcatca cctccatcaa ttaatatatt cttatttgtg ggcgtttgaa ctaaaatact
    25501 atcaccttgt ccaacatcaa tcatatgtat agatagtaga gattttttgt cacagccgat
    25561 taaaagtgat attataataa gtattgataa aaaaatttta tttctcaata aaaaatcact
    25621 ccattcatta catgtttata taaatttatg atgggtaata taagatatat atggcttatt
    25681 atattttata ttttaaacaa tataaatgaa attaatacta taataaaatt ggagtttttt
    25741 atatatacaa aataaaattt ttaaaattaa gcaataaaaa ggcaggagga ttttatgttt
    25801 ttcaaagata ttgaactaaa ttcaaaaaaa gagttagacc catattttga tttagtagat
    25861 tatgaagctt gtgagtactg ttttagtact ttatatatgt ggcaacatgt ttataagaca
    25921 ggatattata taggtgaaga ttttgccgtt ttagttgggg aatatgaggg agatagcttc
    25981 tcaatattac cacttgctaa gaaagataaa cttccagaag ttgtagattt tgtccttgaa
    26041 tatttttcta aaaataataa aaaaatatac ttaagaggta ttactactga agttgtagaa
    26101 tttttaaaag aaaaatatcc agatagattt gagtatatag aagaaagaga tttatttgac
    26161 tatatttatg atgcagaaag tttaagaact ctagctggta aaaagaatca aaagaagaga
    26221 aaccatataa actatttctt aaaagagtat gcaggtagat atgaatctaa attattagat
    26281 aaagaaaact ttgatgagtg tctagtatta atgaaggaat gggaaagtaa taaggaagaa
    26341 aataatgaat ttgatgaaag tatggatgat gaattaatag gtatcaaaaa gatatttaac
    26401 cattatgaca tattaaaaga taaggtaaaa gtatttggtg tttatgtgga tggaaaatta
    26461 gaagctttta gtataggaga acttttaaat ccaaatatgg cattgattca tatagaaaaa
    26521 gctaatccag atataagagg tctgtatcca tttataaatc aacagttttt ggtaagtgaa
    26581 tttaaggatg ttgagtttgt aaatagagaa gaagatttag gtattgaagg attaagaaaa
    26641 gctaaacttt cttatcatcc ttgtagattt gttgaaaagt acagtgttag ggaggcttag
    26701 tagactatat ggagattagg tatgctaaag aagaagatat agaaagtata aaagagattt
    26761 ggagttattg ctttaatgat actgagagtt ttatgaaata ttattttaat gataaatata
    26821 aatctgaaaa tactgtagta gctttagatg aaggaaaaat tatttcctct cttcagctaa
    26881 atcagtataa gttactatta aataacaagg tatacaatac atcatatgta gtaggcgttt
    26941 ctacacttcc agaaggaaga ggaactggat atatgagtaa agtaattaaa tttactttaa
    27001 acgaattgta taaaaaagga caattagttt ctatattgat gcctattgac tataggcttt
    27061 atagaagatt tggatatgag cattgttatg accagattga atatactatt aacacagatg
    27121 atttaaaaaa ttttaagtca agtggaaaaa tgataaagtc taatttatca caaattgatg
    27181 atttgatacg aatagataga gcttttttaa atgaggttaa tggtaatgtg ttaaaagatg
    27241 aacattatta taaaaactta tttaaagaga ttcaaagtga agatggtttt ttgtacattc
    27301 atgaaggaaa tgaaaaagat ggatatatag tttattttat taatgaagat aaaatgtttg
    27361 tcagagagtt attttataaa aatatagatg cccttaaatc aatgcttaaa tttatataca
    27421 atcacaatac tcaatgtaag atagttacta tatctactcc tataatagat aagataagat
    27481 ttatattaga caaccctaag gatagtgaga taaaaataaa accttttatg atgggaagaa
    27541 ttataaatgt aaagaagttt attgaagatg tagatattga gaatgatatt aatagctcat
    27601 ttaatttatt aatagaagac aagtttataa atgaaaataa tggtttattt aaaatttcta
    27661 tacaaaataa gaaggtatct gtagagcaat tatataaaaa agatgaagag aagcctcaag
    27721 aagattttga tgttaaatta gatataaata ccttaacaca gttagcattt tcttatatag
    27781 atgtaaatga agctattttc ttaaatgata taaaagatgt ttcagaagaa acactagaaa
    27841 tacttaattg tattttttct aaaaaaaata actatataaa tgaatatata taaatagagt
    27901 acgttaaaag attataaaaa tcttttgacg tatttttttg tttatataat aatttacctt
    27961 gtttaaaaat tttctatttg aaaataatct aaataatatg cttttatatg ggagtgatta
    28021 taattcaaat aagaagacct ttattaatta tattagtgtt tgtgatagct atatcattta
    28081 tcattacaaa taatacaaaa aacaacgaag aaattaatga taagataata actatacaag
    28141 gaattgtcaa gggaaaaatt gaaaagaaaa gatacaatca gtataaggta ggagtttttt
    28201 taataaatga ttatacaaaa aataaaaatt tgaagattgg tcagaaagtt aatattacag
    28261 gaaaatttaa aagtttagat aaaatgaagt atgacgattt tgattatgga aggtatataa
    28321 aaagcactgg atataaaggt atagtatata taaataacta taaaattatt gataaaaata
    28381 aattttattc tttaatagga gaaataaagt tttatattag caagacttat aggtacttat
    28441 ataagaaaaa ctcggatttt ataaattcta tactattagc agaagttgaa aatttgagtg
    28501 aagaacaaaa agaaattttt accagaacag gaactagcca tgtaatatct atatcaggtc
    28561 ttcatacagg aatattatgt ataattatat cctttctatt aagaggtata aataaattgt
    28621 ataaattatt aatactgtcg atttttataa ctttatattg tataatggta ggtgcgtctc
    28681 catccataat taggtctata gcatttgtta tgatttttta tttatcaata tttattgata
    28741 gaaagaaaga tggaatatcg gcattgtctc taattgggat aattttaatt atgaataacc
    28801 cctatgttat atataatgta agttttcaat tgtctttttt agctacactt tctatattaa
    28861 tattctataa taaaataaat agtattataa aattaagtat ggtatcattg acaatatcat
    28921 caaatatatt aactttacct ataatttatt atacatttaa aggtatacca ttactttcaa
    28981 ttataggaaa tttaattata gtaccatttg tgggagtaat aatttattta agtattgcaa
    29041 gtttaatcgt atttaaagta agtgtagtaa tagctaaaat tatatccttt tttaatagta
    29101 cattgataga aagcatattt tttttactag aaaaaatcag caatttaagt tttgcataca
    29161 ttaatataga aaaacctaaa ttttatattg ttatcattta ttacatagga gtgttttttt
    29221 acatatttta catagaagga aaagagataa aggagcaaga gaatgaatta caaggatatt
    29281 ataaggaatg taaaagagaa aaattttgaa aaaatgtatc ttttttatgg aagagagtat
    29341 tatttaattg agaatgcaat aaaagcattt aaagatagtc taaacgaggg aatgcttgat
    29401 tttaatttag atataataga tggaaaggaa atagtcttaa atcagcttat aagctctata
    29461 gaaacacttc catttatgga tgatagaaaa atagtaataa taaaagactt tgaactatta
    29521 aaaggaaaga aaaagaattt tacagatagt gatgagaaat acttaataga gcatttagat
    29581 aatattccag acactacaac tatagttttt gttgtatatg gtgatgttga taaaagaaag
    29641 tctctagtta agaaaatagg aagcaatgga atcgtttttg attgtgacaa gctttctgat
    29701 atggatttat ttaaatggat aaaaaaatct tttgcattaa atgatgttat aatagataac
    29761 tctcaaataa tgtactttat cgaacaagag gggtatagag ataagagcag tgaaaagaca
    29821 ttatctgatt tagaaaatga aataaataaa ataagttcat ttgttggtaa agggaataat
    29881 gtaaccaatg atgtaattga taaattatct caaaaaaaag ttgagaatga tatattcaaa
    29941 ttaatcgatt acattggaga gcaaaatgct tctaatgcaa tgaaaatatt aaatgatatg
    30001 atacaagaag gcgaatctgt attaggtata ttttctatga tagcaagaca atttaaaata
    30061 attatgcaag taagacagtt acaacttgat ggatattcaa caaaacttat agctgataaa
    30121 ttaaaaatgc atcaatttgt tgtaggaaaa gcattaaagc aaactaaaaa tttttctgat
    30181 gatataattg tggaaatatt aaactatata ctagaaagcg attataaaat aaagacaggc
    30241 cttataagag ataccttagc agttgaaatg ttggttagta gatactgtaa aagggaagca
    30301 atataaaaaa tctatatatt aataaaaaat aaatagcaag atatgttata gtttagagta
    30361 gatgtaagct aaattaagtt taagtatata caatcaacta taatatgtct aactatttat
    30421 tttttattgt ataaatttac aaaataaaaa acccctacat aggggttatt atatataaga
    30481 aatataaact ggtaattaag cgttcatacc gtttaatttt tgagctaatt tagctacttt
    30541 tctagctgca gcattcttat gtatagttcc tttagaagct acttggtata ttcttttttg
    30601 agcgtattgg aacttagcaa cagcatcctc tctgtttcca gctgcaacag catcttcgaa
    30661 tcttcttatt gcagttttta tttgagattt tctaactcta tttaaagcag ttttcttttc
    30721 gataacactt attcttttct tagctgattt tatatttgcc accgtgttca cctccctgta
    30781 tttttttatc atattcatcg tcaacatatt agattttaac agaaataaat ctaaaaatca
    30841 aggattatta tttatatatt ttaataatgt tttttatttt gattttttag actgtagatt
    30901 gtgtataaat aatttgcaat atcttgtttt taggttggta tattttgtgt tttaaatatt
    30961 ttgacatata taaattaata ttttattttt gtaacaaata ttttgagata atacaaatta
    31021 ttaacataca ttttgatagt atttccaata attataagat aatacaagaa attactcatt
    31081 tttgtgaatt taataaaaaa ttataaaaat acagaggata cagcagataa gttgatatca
    31141 tatatagatg aaaattgcag tggtcatctt ttcgctttgt gtggggtatc acttggtggt
    31201 caaattgtca tggaactttt atctcgaaaa cctaatatta ctaaaaaagc aattattgat
    31261 ggtagtattt gctacccaag acctcttatg gcaaggtttt gtattactgg tattcgattt
    31321 tttggaggac ttttatttag taagaaggct tgtcgctttc aaattgctat gatgccaaaa
    31381 ttgttacctg aaaatatgca atatccagat gaaataaaag catattatat gacagatatg
    31441 ccacatgtaa gaaaagaaac attctataat atgtatcgta cttacatgat gaactacata
    31501 cttaaagaaa atgttaaaaa aaccacagca caagtaatgt actggtatgg agaaaaagaa
    31561 atgaagtgcg ttaaaaaatc tgcaaaaatg tttcagtctt atgtaccctc ttgtgagatt
    31621 tatgaagcta agggctataa tcatgggtat ttatcgcttt accttccaaa tgaatggttg
    31681 gaaattgcgg aaccattttt tcaaaaggaa taaaggtgtt aggtgattat tgtataatta
    31741 ttgctgtttt tttatatagt aaataaatta ggtatgatat aaaaaaatta ttttggtcaa
    31801 tatattagtg aaagcttaat aggaaaatta taaatagatt aaaggtaggg cctatataaa
    31861 tagtttctac ctttttctgt ttgtaaataa atgatagata agaaagttta ctgacaaatc
    31921 actgaccaaa cccaattttc ttacattgaa agccttaatt ttacttgttt taaataaatt
    31981 tacaatttct tgttataaaa tactaaattt tgttaacaat tataattagc atttaattta
    32041 tactggaggt ttatatgatt aatgtaagaa cagatttagc tttagaagct agtgaaatgt
    32101 gtgaaaagtc tcaagaagga agtagcattc ctggtgtaaa aatagaaact aaagaattag
    32161 aaaattgtat tgtaactaag gttgaagtaa tagacgaaca aggttcagaa ataatgaata
    32221 aagatatagg aaaatatata actctggaaa gtaatcttat gaagtttgat gatgatgaat
    32281 caagagaaga aatgataagt tatctaaaag atgaactggt agacatattt ggacaagacg
    32341 aaaataaaaa aacgttagta atcggtcttg gaaatagaaa tattacttct gatgcactag
    32401 gacccaaaag tgtatctaaa acacttgtaa ctagacatct ttttaaaaat tataataaag
    32461 attatgatga tgattttact gaggtatcag ctttaagccc aggagttatg ggagttactg
    32521 gaatagagac tagtgaaata gtaaagtcat tggttgaaaa agtaaaacca gatagagtag
    32581 tagcaataga tgcattggct tcgagaaaaa tggaaagagt aaactctact atacagatat
    32641 caacagcagg aatatcgcct ggtggaggtg ttggcaatac aagaaaatct ctaactaaag
    32701 aaactttagg tgtggatgtt attgcaatag gagtgccaac agtggttgat gcagcaactc
    32761 ttacaataga tgttttggac atggcaatag acaatttaat agctcagtca gaagaaacag
    32821 aaagttttta cgaaatgttg aaaaaactta aagaagaaga aaagtatcat ctaataaaag
    32881 attcattaga cccatatgac aagaacttga tagtaacacc gaaggatata gatgatacaa
    32941 tcgaaaatct atctataata ataagtgaag gtctaaatag gtctttacat ccaggtagat
    33001 tggtataaaa taaggaggag caattatgtt taaaaaatgc attaaagtag taaccttgac
    33061 ttttatatta gcatgcattt taccaggaaa atcattagct ttgaatcagg atgatttttt
    33121 aaagttttta gtaaattcat cttatccaga agctaaagtc gaaggaaatg atacagaaga
    33181 taaaaagaat aataaaaata aagaaacaag caaagaaaat aaggaagaaa gtaaagaaga
    33241 aaaaactaaa tctaaagatg caagtaaagt tgataataaa aaagagagtg aaaaagaata
    33301 tataaaactt tatgttggta aagaaaatgt tccagatatt gagtcaaaaa attcagacac
    33361 aactgaaact aacgcaacat ctagttcaga ttataaggat gacctaagag taactaaaga
    33421 aaatccaaga attttgatat atcatactca tggatgtgaa acttattcaa attcaccaga
    33481 tggaaactac cattcaagag ataagaaaaa ttcagtaatg gaagtaggaa gtgcattaac
    33541 tagtgcttta gatagcaagg gatggggtgt agttcataca actaagtacc atgactatcc
    33601 atcttataat aactcttatg caagtagcct aaaaacaata caaagtatat tacctaaata
    33661 taattcagtg gacatagcga tagacttaca tagagatgct agggatttaa ctaatccagc
    33721 cactaaggaa aaagaccatt taaaatatac aactatgata aatggagaaa gggtatcaaa
    33781 attcttcttt gttgtaggag gtaaaaatac aaatagaaaa caacttagag ctttagcaga
    33841 agacataact gcttttgctg agaagaagta tcctggtttg gtatctccaa tagtagaaaa
    33901 agactatgct agattcaatc agtttgcagt taagaatcat atgttagtag aaatagggaa
    33961 taacgcaaca agcgtagaag aatctaaggc tactacaaag tatctagctg aaattttgga
    34021 tgaatatttt aaacaaaaaa attagagttt taaggtataa ttaggagcat gttaaatgag
    34081 ccgattagaa aaaaatatag aaagtaaaag taaattaaga aaatacaagt atattatgag
    34141 aattatgttt ttgattacta tgattatatg cacatcagtt tgtgtattta tagtagatag
    34201 taatgcaaaa agtatgctag gaatgaaaca atatgatttt cccaatatta aatttgatat
    34261 aacaaaattt gattttgata taccgaactt tgatatacat gaaatcataa gaaaatttaa
    34321 taagtagtaa taaatgaata aggtttattg atgaaaataa gccttatttt agttatatat
    34381 ctttaatgta taaaataaaa attcactaac tgtattttat aggatttact ttaagtttat
    34441 gatattatat aatatttagt gttagacttg ataatccaca tataatgtgg ataattttgt
    34501 ttagtgccaa ttagtttata ttcaaaaatt ttaaatttgg tatataaaga gtttttagat
    34561 aatgtaaaat aataactata agaataatca agaggaggga actttaaggt ggacaataaa
    34621 caaagtagaa ctagaaattt tagtataatt gcacatatag accatggaaa gtctacctta
    34681 gctgatagat taatacaaca aactgggctt gttagtgaaa gagacatgaa aagtcaatta
    34741 cttgacaata tggaccttga aagagaaaga ggaatcacta taaagcttca aaacataaga
    34801 ttaatgtata aagcgaagga tggaaacgaa tattatttaa atcttataga tacacctgga
    34861 catgtagact ttaactatga ggtatcaaga agtttggctg catgtgaggg agctttatta
    34921 gtagttgatg cagctcaagg tgttgaggca caaactttag ctaatgttta tcttgctata
    34981 gaccaagatt tagaaatatt accaataata aataaaatag atttaccaag tgcaagacca
    35041 gaggaagtaa aaaatgaaat agaagattta atagggcttg actcaagtga agcacctctt
    35101 atctcagcta agactggttt aaacatagag gatgttttag aagacattgt aaaaaatgtt
    35161 cctccaccta aaggagataa tgaagctcca ttaaaggcat taatattcga ttcttactat
    35221 gatgcttaca aaggtgttgt agcctatgtt agagtatttg aaggaactgt taaaaagggt
    35281 atgacaataa aaatgatgaa taccaataaa aagtttgagg taactgaagt tggtgttatg
    35341 gctccaggtc aaactgaact tagtgaatta tcagcaggtg atgttggtta tattgcagct
    35401 agtataaaag atataagaag ttgtcgtgtt ggtgatacaa taacagattc aaataatcct
    35461 acagaagaac ctttaccagg atacaaaaaa gctactccaa tggtatattg tggtatatat
    35521 ccaggagaag gagaaaaata tgaaaatgtt agagatgctc ttgaaaagct tcaagtaaat
    35581 gatgctgcac ttgaatatga agctgagact tcagccgcac taggatttgg ttttagatgt
    35641 ggtttcttag gtcttttaca tatggagata atgcaagaaa gacttgagag agaatttaat
    35701 cttgatataa ttactacagc accatctgtt atatatagag ttacaaaaat ggatggagaa
    35761 gtcgtaatga tacaaaatcc tgcaaacttg ccagaaccat ctgagataaa gatgatagaa
    35821 gagcctatag taaaaggaga tataatagtt cctaaagact atgtaggtgt tgttatggaa
    35881 ctttgtcagg aaagacgtgg aaatatgttg aacatggagt atatagatga gagaagagta
    35941 atgcttcact atgaccttcc tctcaatgaa gttgtttacg atttctttga tgccttaaaa
    36001 tcaagaacta gaggttatgg ttctcttgat tatgaggtta aaggttatgt agcatctaca
    36061 cttgtaaaac tcgatatatt aattaataaa gaacaagtgg atgcacttag ttttattgtc
    36121 catgaaacac gtgctttccc tagaggaaag gcaatgtgtg agaaattaaa aggggaaatt
    36181 ccaagacatc agtttgctat accaatacaa gctgctgttg gtaataaggt tattgcaaga
    36241 gaaacaataa gtgctctaag aaaagatgtc cttgctaaat gttatggtgg ggatatatct
    36301 cgtaagaaga aacttcttga aaaacaaaaa gaaggtaaga agcgtatgag acaaattggt
    36361 tctgttgaag ttcctcaaaa agcatttatg tctgtgctta aattagatga ataaatcctt
    36421 ataaatttag ataaagatat ttaaaagcta gagtgatttt agaattattt ctaaattagt
    36481 ctagcttttt tatggtatat tttaagtaaa ctcataaaga atataagtaa gaatattaaa
    36541 gaagaataaa aaggtgatat ttatgattaa tatagaaatt cctaaaaaag tagattatat
    36601 aattaaagaa ttagaaaaga atggttatga agcttatata gttggaggat gtgttagaga
    36661 ttgtttatta gaaagagttc caaacgattg ggatataaca actagtgcta gaccagaagt
    36721 ggtagtagaa ttatttgaaa aaacaattcc aactggtata caacatggaa ctgtaacagt
    36781 tatggttgaa catgaaccat ttgaagtgac aacttataga attgatggaa attatagtga
    36841 tggaagacat ccagattcaa tagaatttac aaataacata gttaaggact tatcaagaag
    36901 agattttacc atcaattcaa ttgcatacaa ttcagaaaca ggattagtcg acccatttaa
    36961 tggatatgaa gatatacaaa ataaatatat acgttgtgtt ggaaatccag tagataggtt
    37021 tgaagaagat gcgcttagaa tgcttagagc agttagattt tcagcacaac ttaattttaa
    37081 tatagatgaa ggtactgagc aaagtattca taaaaaatca gatttgataa aaaatgtttc
    37141 tattgaaaga atccagacag agtttaataa aatcttagta tctgattcat ctaaattaaa
    37201 cctattaaaa tcaacaggtt tgttgaaatt tataattcct gaaatatgtg aattggaaga
    37261 tgtcactcaa cacaatccat atcatatcta tgatgtacaa aaacatactt taatagctac
    37321 agaagtaatt gaagatgaac tgtatttaaa acttacaatg ttgtttcatg atttaggtaa
    37381 aaaagtaact aaaacaactg ataaaaatgg tgttgaccat ttttatactc atagtagaga
    37441 atctgtaaag attgcaaaga agattttgaa aagacttaag tatgataatt atactattaa
    37501 taaagttttg atattgatac aatatcatga ttatagaata gaacctaaaa ggaagataat
    37561 taaaaagtta ttaaataaac ttgaagatgt tgaattattt gaagatttaa taaaagttaa
    37621 ttgggctgac acacttgcca aaaatccaaa atatgcaaaa caaaagatat taaatcttat
    37681 tgagtgtgaa aaagaattta aacatataat aaatcaaaag gagtgcttta atcttaaaga
    37741 tttagctatt aatggaaaag atttgatatc tataggtata aaaccaggta aagacatagg
    37801 acatatttta aataatatgc ttgaaatagt tataaataat ccagagctaa atgaaaaaga
    37861 aatactaaaa gaaaaggcat taaatatata tacattttag attcaaatat aaaaaattta
    37921 atagatttaa gaaatataga agaaaatatg tatttagata aaataaataa tttttagaga
    37981 atattttaga gattacgatt gtatgagttt taaatgcata gggatttact ctaggattat
    38041 agactaatat aaaaaaaaac tttgggaata ctaaaaccat aaatttataa aattaatatt
    38101 ttatatactg taaaacagtg aggaggaaca gtatgcatac tcaactacaa aagactattg
    38161 gtctttcagc agctctttct actgttgtag gtatggttat aggttcggga gtttttttta
    38221 agccacaagc aatatacact acaactaatg gagctccagg gctaggtatt atagcatggc
    38281 ttttaggtgg ttttataaca ataactgctg ggcttacagc tacagaaatt tcagctgcta
    38341 taccgaaaac tggtggtatg atgatttata tcgaagaaat atatggagaa aagttaggtt
    38401 ttttaactgg atggatgcaa actgtactat ttttcccagg tacatcagca gcactaggag
    38461 taatatttgc tcaacaagca tctgaacttt taggaatgag cccaaataat atggcaaatg
    38521 tacttcctat agcgattgga gttatactat ttttagcatt attaaatata ataggttcat
    38581 ctttaggagg aaaagttcag acagtagcta ccattggaaa gatgatacct ttaattttaa
    38641 taataatctt tggatttatt aaaggtcaaa gtagtgaagt gttaaatcca tttgtaggag
    38701 atggtgtaaa tgcatcaaat gcacttggac aagtattaat agctactttg tttgcatatg
    38761 atggttggat aaatgttgga gctatatcag gagaaatgaa gtctccagag aaagacttac
    38821 caagagcaat agttggtggt ttatcattag ttatggcagt ttatattata ataaatatag
    38881 cttatctttg ggtagtacca gcaagtgaat tagcaacagt tacttcacca gctacattag
    38941 tagcaacaag attgtttgga aatataggtg gaaaagtaat aactatgggt atattaatat
    39001 cagtatttgg cacattgaat ggatatttat taacaggttc aaggatacct tatacattag
    39061 ctgaaatggg aactttacca gcatctaaag ctcttttaaa agtaaattct ggaggttctc
    39121 ctgtaaattc aatactactt ataactgcgt tagcatgtgt atatgcatta tctggtcaat
    39181 ttaatctttt gacagattta actatatttt caatatgggt attttatgta ttaactttta
    39241 taggtgtcat gaggcttaga agacaaaagc cagatttata cagaccatat agagtccctt
    39301 tatatccaat aataccgatt atagctatat taggcgggct gtttgtaata ataaatcaaa
    39361 tattaacttc aacagttata tctctaggcg gaatatttat aacactatta ggtttaccag
    39421 tttattatta tatgaaaaaa agataactac ttaatttaag ttagatgaat ttgggtaaaa
    39481 gtaaaaatta acttttatcc aaatttttta tactattaca caatataagt attatatatt
    39541 acttgatgtg ctattttgtt tgatttataa tttagtaatt gatgttttaa gataatttaa
    39601 gaaatgagga ataaaaaatg ctaggacttt atgtacatat tccattttgt gtgaaaaaat
    39661 gtaagtattg tgactttaat tcttataaaa tggacataga tttaaaaaaa agatatatag
    39721 aagatttaaa aatagaaatg gaattatata gtaataaatt atataaagat aataaatata
    39781 aaaataaaga atgttgtagt ctaaataaaa atgacaaaat aacgagtata tttgtagggg
    39841 gaggtacacc tagtatacta acatctgatg aaataagaga agtatttatg agtataaaag
    39901 aaatgtttta catagatgat aatgcagaaa taactataga gtgtaatcct ggtacattaa
    39961 cattagaaaa attaaaaact atgaaagata ttggtataaa tagacttagt atagggctac
    40021 aagctattca agaaaagcat ttgaatttta taggaagaat acatacttat gaagaatttg
    40081 agaaaaacta taaagatgca ttaagtgtag gatttaaaaa tattaatata gatttaatgt
    40141 acagtcttcc aaatcaaact ctatgtgatt ggaaggaaac tcttgaaaaa gttgtacact
    40201 taaatccaac acatatatca gcttattctc ttatactaga agaaggcact gaactataca
    40261 atatgtatga aagtaataaa tttgaactta tagatgaaaa tatagatata gaaatgtatg
    40321 aatatacaat aaactaccta atgtcaaaag gatataatca atatgaaata tcaaattact
    40381 caaaagaagg ctttaattgt aagcataata ttttatattg ggaatgtaaa ccgtatatag
    40441 ggattggagc aggagcttct ggctatatta atgagaacag atacaataat gtagaatctt
    40501 tagaagacta tcatttaagt ttggtaaaaa gggaaaaacc aatacaagaa aatgaaattc
    40561 tttctgagaa agatatgata gaagaaaaga tatttatggg gcttagaatg aataaaggta
    40621 taaaatttga agatttcaaa aaaaaatttg gaatagattt taaagataag tatagtaagc
    40681 aaatagaaat gctatcagct agaaagctta taaatcagag ctttgaaggt atacaattaa
    40741 ctcaaaaagg aagagaaatc tctaatagtg tatttataga atttatggaa taattattaa
    40801 ggtgttgaca aaataaaatt ataatggtat ataatatata taatcttttt agcactcgaa
    40861 cttagtgagt gctaacagct aggaggtata ataatatgga attaaatgaa agaaaattaa
    40921 atatcctcaa agctatagtt aaagattata tagaaacagc tgaagctata ggttctagaa
    40981 caatatctaa aagacatgat ttaggtgtta gtgctgctac cataagaaat gaaatggctg
    41041 accttgaaga attagggtat ttaattcagc ctcatacttc tgcgggcaga gttccatctg
    41101 aaaaaggcta taagttatat gtaaactctc ttatgagtaa aagcgagttg gatgataatg
    41161 ataagattct tattgaacaa tgtatgaatc ataatataaa tcatataaaa gaattgattc
    41221 atgaaacttc taagctatta tctcaactaa caaactatac aactgtagca gttactaaga
    41281 gtttagtaaa tcaaagtgtt ataaagcaca tacagttggt tgctatgaat gataataata
    41341 ttttacttat agttgtaaca gataaagggg acttgaaaaa agctaacctt acaactaatg
    41401 tatatttaga tcaatctaag ttaaatttga tttctgataa tcttacaagg aagctcttag
    41461 gtaaaagtat aacagatttg gatgataatc taattgcttt tattaaatac gaaataagtg
    41521 agtattctgg gcttatagat gagcttttaa atgctttgaa ctcaaatatg aaagaagaag
    41581 atttttctct atcattaaat ggagctacta acatatttag ttatccagaa tttaatgatg
    41641 tattaaaagc aaagtcattt ttaaatatgt tggagaaaaa ggaaacaata gctgacataa
    41701 ttaaatcaaa gggaatacaa aaagacaatc taaatataat aattggtagt gataatgatt
    41761 gtgaactggc acaggattgt agtatagtta cagcaactta taatgtagat agagacttgg
    41821 ttggacgaat aagcttcata ggtcctacca gaatggatta tgctagaatt tactctataa
    41881 taaattatat gagtttatta attaatagaa agtaaagaaa ttttaaattg cgaggtgtaa
    41941 agtcttggat aaaaaaaatg agcaacagga agtaagagaa gaaaatgata cttctattaa
    42001 ccaagaatcg gaaactcaag tagagttgga agaggaagtt gttaatgaag aatgtgaaac
    42061 atcaaatgaa aaaactgatg aaaaagaagt tgatgatgaa aatgtaacag atataaattc
    42121 taagttagca gaaaaaaaat tgcagaatga gttggatgaa ttaaatgata aatatcaaag
    42181 acttcaagcc gaatatgcaa attacagaag aagaactcaa caagagaaag agacaatagg
    42241 tgtatttgca aatgaaaaaa taataactga gttgatacca gttatagata gtatggaaag
    42301 agccttagat gcatgtgaag ataaggaaga tactatgtat aagggtataa gccttgtaca
    42361 taaacaatta atagacactt tagtaaaatt tggagtagaa gaaatagaag cagaatctaa
    42421 ggaatttgac cctaatttac atctagcagt tatgcaagaa agtgtagatg gaattgaagc
    42481 aaaccaaata gtaatggtac ttcaaaaagg atataagcta ggaactaaag ttgtaagacc
    42541 ttcaatggtt aaagtttctt gctaagtata aattaaaggt tacattattt aacctaatat
    42601 aaaatattaa aataagtaaa acttaattat ataattactc gaggaggatt ttagtcatgg
    42661 gaaaaataat aggaatagat ttaggaacaa caaattcatg tgttgcagtg ttagaaggtg
    42721 gagaagcaca aataatagca aatagtgaag gtatgagaac tactccatca gtagtagcat
    42781 ttacaaaaga tggtgaaaga atagttggag aacctgcaaa aagacaagca gttacaaatg
    42841 cagataaaac aataacttct ataaaaactc atatgggaac tgattataaa gtaaatatag
    42901 atggaaaatc atatactcca caagaaatat cagcaataat attacaaaaa ttaaaatcag
    42961 atgcagaaag ttacttagga caaacagtaa cagaagcagt tataacagtt ccagcttact
    43021 ttacagatgc tcaaagacaa gcaactaaag atgctggtag aatagcaggg cttgatgtta
    43081 agagaataat aaatgagcca acagcagcag cacttgctta tggtatggat aaattagacc
    43141 aagaaaagaa aatattagta tttgacttag gtggaggaac ttttgacgta tctatacttg
    43201 aaataggaga tggaactttt gaagttttag ctacagctgg taacaataga ttaggtggag
    43261 atgactttga ccaaatagta atagattatt tagcagagga atttaaaaaa gctgaaggtg
    43321 tagatttaag aaatgataaa atggctcttc aaagattaaa agaagcagca gaaaaggcta
    43381 agaaagaatt atcatcaaca atgagttcaa acataaactt acctttcata actgctacag
    43441 cagaaggacc aaaacactta aatatagact tatcaagagc taaatttgaa gaattaacta
    43501 gaggtttagt tgaaaaaact atggaaccaa ctaagacagc tttacaagat gcaggacttt
    43561 ctacaggtga tatagatgat gtattattag taggtggttc tacaagaata ccagcagtac
    43621 aggaagctgt taagaagttt ataggaaaag agcctcacaa aggtataaac ccagatgaat
    43681 gtgttgcagc aggtgcttct atacaagctg gagttttagc aggggatgtt aaagacttat
    43741 tattactaga tgttactcca ttatctcttg ggatagaaac tatgggtaat gtaatgacta
    43801 agataataga aagaaatact acaataccaa ctaagaagtc tcaaatattc tcaactgctg
    43861 ctgataatca aacagctgtt gatatacacg ttcttcaagg tgaaagaagt atggcttatg
    43921 acaatacaac tttaggaaga ttccaattaa cagatatacc accagcacaa agaggaatac
    43981 ctcaaataga agttactttt gatatagatg caaatggtat agttaatgtt tcagctaaag
    44041 atttaggtac aggaaaagag caaaaaataa ctataacatc aaacactaat ttatcagaag
    44101 cagaaataga gcaaaaaata aaagaagcag aaatgaatgc agaagctgac aaacaaaaga
    44161 aagaaaaaat agaagcattc aatcaagctg aatctactat atatcaaact gaaaaaactt
    44221 taaatgaact tggagataaa ataagttcaa gtgaaaaaga ggagatagaa aaagctatag
    44281 cagacttaaa aactgtaaaa gataatcaag atgctacagc agaagaactt aagaaagcta
    44341 cagatgaagt aatgactaag ttccaaaaag tatctcaaga gatgtaccaa aaagcagctc
    44401 aagagcaaca agcagcacaa ggtgcagaac aagctcaaga caatggacct aaagatgaca
    44461 atgtagtaga tgctgacttt aaagaagtgg atgaagataa ataagctata taatatgtaa
    44521 cactaaatga tagttagagc atatatgatt tgtgaaaatc atatagatgt taaagatata
    44581 tggacaatac acatcataaa gaatataata tatcatagat tatataactt aaagtagaat
    44641 ataagaatta atgatagctt gtagtttatt attctacaag ctatcgtttt gtaaaatgaa
    44701 ggtggtgtca gtttttgagt acaaaaaggg attattatga agtcttaggt atcagcaaag
    44761 gtgcagaagc tcaagagata aaaaaagctt acagaaaatt agcaatgaag taccatccag
    44821 atagaaatcc tggagataaa gaagcagagg aaaaatttaa agagataaat gaagcttatg
    44881 aagtcttatc tgatgataca aagagaaaaa cttatgacca gtttggacat gatgggctaa
    44941 atggtcaagg tggttttggt ggtcaaggag gatttggcgg tcaaggtttt ggtggttttg
    45001 aagatatgtt cggagatata tttggtgaca tgtttggagg aagcttcgga ggaggaagaa
    45061 caagaagaag aggacctcaa cgtggtgcag atataagaca aagtgttact atatattttg
    45121 aagaagctgc atttggtaaa aagatgtcta taaaagtaaa tagaagtgaa gagtgtgaag
    45181 aatgtaatgg aactggagca aaaccaggaa catcaaagaa aacttgttca acttgtaatg
    45241 gaacaggtca agttagaact gttcaaagaa ctccttttgg taatatagca agttcaagac
    45301 catgtagtac ttgtaatggg actggagaag tgattgaatc tccatgtagt aaatgccatg
    45361 gaactggaaa tacaagaaaa gttaagacta tagaagtaga tatacctgct ggtatagatg
    45421 atggtcaaat gataaaactt tctggtcaag gtgaagtagg agaaaaaggt gctccaagag
    45481 gagacttata tattgtagtt aatgttaagt cacatccact atttactaga gatggaaatg
    45541 atatttattt tgaaatgcca attacatttg ttcaagcaac tttaggtgat gagatagaag
    45601 tacctacttt ggatggaaaa gttaaatata gtgtaccaga ggggacacaa actggaactg
    45661 tatttagact taaagaaaaa ggaatcccta gaattagagg taattcaaga ggagaccaat
    45721 atgttaaggt tgtagttgaa attcctaaaa aattaaacga taagcaaaaa gaactattga
    45781 gagaatttgc gaaggagtgt gggtcgaacg tccacgaaaa gaagaaaacc ttcggacaaa
    45841 agatagaaga tatgtttaag aaaaagtagt taaagtagcc aatatataat catatttttg
    45901 aaatcttagt tatttataag attgtcaaag gagatattat gatttttata ttggctattt
    45961 ttgtataaaa aataaatatg cataaaataa aactgaatat aaataatttt ctgaaaaata
    46021 cttgtcctaa aatatataat atgctataat ataatcaaat aaaagaaagg ggtgattcca
    46081 gtgggaacgg atgtggcact gccagatgac gaagaaaact ttattgtaat ctacaaaata
    46141 aaattagatg cttttagtgc tagattaagt actggaaaaa ctcatgagct gggataatta
    46201 ttataattac ctagacttaa atttttagta gtaaaatagt aatattatat agacaaggta
    46261 tctaattttt aaatcttttg tatgaattaa aatttttata aaggatatat ctgattagaa
    46321 tgtaattagg gaaacctagt tgtaaattgc ttttagtata tacatgtgta aagaaatatg
    46381 tatatggtat tggttattgt gctagatgca tatgtaaagg aatatgtatt tagttgagta
    46441 tatgtaaaga aatatactta taatctatga aaaaatttta gtataaattg ctaaaacatt
    46501 gagattgttt tttatagaaa gttagtttat accaattaaa aatgtgctta agatttgttt
    46561 gatgtttaat tataaataag attgtagata aaaaaataag tagagacaaa ggtttaaaat
    46621 acttgattta aatatagttt gttttgaaca cttgccaaat taaccaaatt aaaataatta
    46681 ataaaataga catcttctca tagtaaaata tactgtgaga ggatgttttt gctttgttca
    46741 taaactttta tgaaaaattt gcatagtgtc acattttaat atactatata tataataaaa
    46801 tatagataaa attaaatgat tcaaaagaga aaggtgaaaa gagatgtatt atataggtgt
    46861 agacatagga ggaacaggta tacaagcagg agtagttgat aactatggga agataatttt
    46921 taggtcagag tgtaaaacag taattgaaaa aggctttgaa ggaatactta atgacataaa
    46981 aataatgatt tataagttgt tggaagataa taaacttact atgagtgaca taaaatctat
    47041 tggatttggt gttccaggtt ttataaataa agaaggatta gtaacttgtg taaatttaaa
    47101 atggaataaa aaagctttta ataaagagtt aaaaagaaga tttccagatg ttgaaattca
    47161 tggagaaaat gatgcaacag tagcagcact tggagaagca aagtttggaa gtatgaaagg
    47221 tgctaatgtt ggagtattat atactttagg aactggtgta ggtggaggaa tagtaattaa
    47281 tcaaaaggtc ttttctggag cacatggatt gggttcagaa ataggtcatc aaattatagg
    47341 agaaaactat tttaattgta attgtggaaa taatggttgt gtagaaactt tttgttcagc
    47401 aactgcaatt ataaagtatt ctcaaaagct gatagaagaa ggagaaaaga gtaggatttt
    47461 ggatttggca gagggcaatt tagaaaatgt aaatgcaaag atggtgtttg atgcatatag
    47521 agaaaatgat ttagtggcaa ttaaagtaat aaatagattt aaagaatatt tggcaaaaac
    47581 ttttgcaaat acaataaatt ctttagaccc agaaattata tccataggag gaggtatttc
    47641 taaatctagc gatataatac ttgatgggat agaagattta gtaagaaaat ttgtattata
    47701 caaaacagaa gatatagcta caattacatg tgcaacttta ggttcagacg caggaattat
    47761 aggagcagct tttttataaa gtaaatgaac tgcttattgg aggcgggata tatgagtaaa
    47821 acaaatgcta gaagaacgct ttttttgata gccataggtt caggaactat gctgaatcct
    47881 cttaattctt ctatgatttc acttgcttta catagtatac aaaatgattt tcatattagt
    47941 tttacaactg tatcttggat tgtttcagca ttttacctag ctagtgctat tgcacaacca
    48001 gtttcaggta aaataggaga tttaataggt aggaaggtct tatttttgag tggtttgatg
    48061 cttgtaattt tatcagcatc catagtgcca cttgttcaat cattctttat attgattttt
    48121 ataagagtaa ttcaggcaat tggaacgagt acactatatc catctggagt tgctcttata
    48181 caaaataata taaaagaaag acagtcttct gcattagcag ttctaaccat ttttgcttca
    48241 actacagcag gattaggtcc aacgcttgga ggattattgt tggatttagg aggatggcat
    48301 gctatatttc ttgtaaatat acctgttgtt ttggtttcta tatgcttagg gtatttttta
    48361 ttcccaaaag aagtaaaaga aaagaaatct ataaaagaaa ctctgaaaaa tgttttgtca
    48421 agattagata ttattggcat acttctattt tcaattgcaa tgatttttat attattattt
    48481 ttgctatcta tgaaggagtc tttcaactta gaacaacttg tatttggtat aatactgatg
    48541 tatcttttta tttggcatga attgagaaca aaattaccat ttatagatat taagcttttt
    48601 gtgagtaacc ctaaattgtc aaaagtttac ttgcaattta ttatattaaa tttctttaat
    48661 tatattttgt tttttggtct tcctagttat tttcaagatg cattacacta tagtgcaaaa
    48721 tcgactggat tatttatgct atttatgtct ggtataggta tatttatatc tccattaact
    48781 ggaagatgga tagataaatc tggaactaga tttcctcttg ttacatcatc aatctttatg
    48841 tttattagtg cagtacttct ttcagtagtt tttattcata taccagtaat aggaaaaggt
    48901 atcatattat cattagcagg tattagttat ggagttggta atgtagccct gcaatcctct
    48961 atgtttgaag aaagtcctcg tgacagtata gggacagctt ctggcctttt tcaaactagt
    49021 cgttatttag gttctatttt agcaactgtt ttacttggaa tggtatttga agtaaatata
    49081 acatcagaac aatttcagat attaggttat gtgatggtgg tcttaggtac aataagtttt
    49141 ttattaaatt ttatactaaa gaaagaatta agaaaagtag aatagtggat ttatggattt
    49201 aataagtcta ataactgata agtttaaaaa cattgtttgt aaaatataac tagtttgata
    49261 tttattaatt ctaagctttg aagcatagag tactcgataa gtatacaata ttttgaatta
    49321 aaattaagca gaaatttgaa ctagtctttc aaatctctgc ttaatttagt ggttaaattt
    49381 ttttatagag aaaataagat ttgacactca gataaaaaat cattgcattt tcaaaattct
    49441 ttaaatcaaa cccaagtatc tcattaatct tttccaatct atatactagc gtgtttctat
    49501 gtaaaaacat actagttgat gtcttagaaa tatttaaatc attatttata aattttaatc
    49561 ctgtatatag aagttcttca tcaatagatt taatcttatt aaaatctatt aatttattga
    49621 gtatattgtc ctcattaatt aaatctaagg ttttatatct aataaggtca aacaaattta
    49681 aaaacttatt ttcagcgttg tcttttataa tatgaggtag taaatcagaa cataactgta
    49741 atctaaaatc aaaatcagct ttactatcta atttaccaag ataaaaaata taagtacttt
    49801 gataagtttc agtttcaatt atattttgtg tagttacatt aatatctaag ttatatttag
    49861 aatttactat aaaaaaacta ttgtgttgta ttatatttat atcttcaaat aaattataaa
    49921 aaatattttt tagatattca aattctatat gaggttggta aattaaataa aagttgcctt
    49981 ttaaattatc aagattattt ttatctagaa aatcaataac ataaatagaa ttattgaaag
    50041 taactaaatg gctactagca tctaactttt ggttttcata tggatagata tttatttttt
    50101 tattaagttg tctttctaaa aaatccttta actcttccat aaagtctcct taaaaataag
    50161 attatattct tatcttatag ccaaagtagt ttctttgtca aatatgtgta ttctactgtt
    50221 atcaactgaa agtgttaagt catcaccaac attaattctg tttttactgt caaatctaat
    50281 tgttatagta ttttcgccta gctttaagtg agcataagtt tctgctccca taagttcttt
    50341 tatttcaatt cttgatttaa aacaagtatc tggattagat ttaataaaag tatcttctac
    50401 atgaatatct tctggtctga tacctataac aacttcatta ttaatataat tgtcttttat
    50461 taaatcatag tgtttttctt tatttaattt aagcttaata tgttcatttt gtgcataaat
    50521 ttcatcattt tcttctatta atgttacatc aataaaattc atctgtggtg ctccaataaa
    50581 tcctgcaaca aatatattag ctggataatc gtatacatct tgtggagttg caatctgttg
    50641 aaccactcca tctttcatta ctacgattct atcagccata gtcatagctt caacttggtc
    50701 gtgtgttaca tagataaatg tagttccaag ctgttggtgt agcttagtta tctctgttct
    50761 catagcagtt ctaagctttg catctaagtt ggatagaggt tcatccatta agaatacctt
    50821 aggatttcta actattgcac gtcctaaagc aaccctttgt ctttgtcctc cagacaatgt
    50881 tttaggtttt ttatttaaaa gaggtagtaa atctaatatt ttagcagcct ctttaacttt
    50941 tttgtctatt tcatctttag gcaattttct aagtttaagt gcaaatgcca tgttatcata
    51001 gacggataag tgaggatata gagcatagtt ttgaaaaacc atagctatat ctctatcttt
    51061 tggttctata tcattgacaa gtttatctcc aatgtatagt tctccttcag agatttcttc
    51121 aagaccagca atcattctaa gtgtagtcga tttaccacaa ccagatggtc ctactaaaac
    51181 gataaattct ttatctttaa tgtctatgtt tatatttttt actgcattaa atccatttga
    51241 gtaaagtttt gatatatttt ttaaaattac ttctgacata atattctcct tgatatttaa
    51301 attttaatta tatagtatca aattttttta ttatattaaa tgtgtaaaat gaacaaatgt
    51361 atttgttcaa tatgtatatt aaaaatttag actaatagtt ttttaattta aaaaatgtat
    51421 tttaatttag aaaagtttta tgtataatag tatatagttt ttagttcaac aacatgggat
    51481 ttaaatgtca atttaatt
//
LOCUS       DAMKOJ010000022        49048 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000022 DAMKOJ010000000
VERSION     DAMKOJ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49048
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.023"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            86..259
                     /locus_tag="PC592_001375"
                     /pseudo
     CDS             86..259
                     /locus_tag="PC592_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
     gene            468..1619
                     /locus_tag="PC592_001376"
     CDS             468..1619
                     /locus_tag="PC592_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF4055366.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRAAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVKKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            1644..2399
                     /locus_tag="PC592_001377"
     CDS             1644..2399
                     /locus_tag="PC592_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HDF4055367.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGVYFLNNNVRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAQGHEPVNISSM
                     CTVFAESEIVSLLAQNISAGEVAAGILKSIANKSTSMLARGEIIDEVAFTGGLAKSKE
                     LVKMIEEILDKKIFIAEDTQIIGALGAAVIGFR"
     gene            2591..4978
                     /locus_tag="PC592_001378"
     CDS             2591..4978
                     /locus_tag="PC592_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HDF4055368.1"
                     /translation="MKRFTSKKVARFVALFLISILVMSTIPASADTSNTLNQIKKAEY
                     SETYKQYLNDVKNGRTEKYNGIIPNPYQLEGTQIKSKGRTAPTSYDPRKLGLMTSVKN
                     QENLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMDGALNYE
                     AMGYLTSCSGPKLEKDIPYNGKISKAQGATKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSAYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKSNFNSNI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGQKPSDDEKMYQHD
                     YASIVPLISNKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTTQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSKFYPCNFTIKAVTEKSSSESVPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGGSIVDALAATPFTSAINSPILLTQKEALNSKTKVEIQRLG
                     AKKVYLIGGENSISKETEQQLKSLNISTERISGSDRYKTSLLLAQKLNSIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNVFVVKNGIKSQNDLIDGLAVG
                     PLGAKTGSPVVLVGDKLADSQKEVLKNKTLEKVTQVGGGANQNAFKELVKLKSVK"
     gene            complement(5201..5434)
                     /locus_tag="PC592_001379"
     CDS             complement(5201..5434)
                     /locus_tag="PC592_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF4055369.1"
                     /translation="MTTTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            5724..6314
                     /locus_tag="PC592_001380"
     CDS             5724..6314
                     /locus_tag="PC592_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4055370.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMELYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRLDKSITCEQLTDIFMKFYRMV
                     DSTSILNLMVNGEFEILVRKLPDAIIEEHFRHDDFEIGEIISCIPNAKNKDIERFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            6428..7273
                     /locus_tag="PC592_001381"
     CDS             6428..7273
                     /locus_tag="PC592_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055371.1"
                     /translation="MIKVDDLSFSYTDKNFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYKGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDKLLKSVGLENKANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVKYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            7270..7953
                     /locus_tag="PC592_001382"
     CDS             7270..7953
                     /locus_tag="PC592_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055372.1"
                     /translation="MRLKNLVLGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMLIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLVDTKSYANFYPFNICISLISGDKNFIVINILILISMIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            7950..8666
                     /locus_tag="PC592_001383"
     CDS             7950..8666
                     /locus_tag="PC592_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055373.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYLLMFDLLLAFITPFMFFFASTMVVLGEIDDSISRYLIVTPLGK
                     TGYLVSRFGIPGILAFIITMILLIFFSLTRISFLLNLSISLLVLLQSVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKVQYILFFLPTFWLSKAFKEDNYIYMFISI
                     IISLIWILLLFKKFSKKIVK"
     gene            8763..9026
                     /locus_tag="PC592_001384"
     CDS             8763..9026
                     /locus_tag="PC592_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055374.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            8998..9453
                     /gene="def"
                     /locus_tag="PC592_001385"
     CDS             8998..9453
                     /gene="def"
                     /locus_tag="PC592_001385"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF4055375.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            9514..9975
                     /locus_tag="PC592_001386"
     CDS             9514..9975
                     /locus_tag="PC592_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HDF4055376.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHILVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTGILKWKNRNFANDISNEHSLDLENL
                     YDGWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWYGNIMF"
     gene            10025..10927
                     /locus_tag="PC592_001387"
     CDS             10025..10927
                     /locus_tag="PC592_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4055377.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSIRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINLLFRHAKECNVHYVLP
                     GTLYLRGITRGIFFDFVKKEFPELFDKLSILYSTGSLNRGYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            11296..12108
                     /locus_tag="PC592_001388"
     CDS             11296..12108
                     /locus_tag="PC592_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF4055378.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPVKYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLFEIENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            13157..13918
                     /locus_tag="PC592_001389"
     CDS             13157..13918
                     /locus_tag="PC592_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF4055379.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQCINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWSGKRVFIIATMALFSGDGSGVLSRMLKKY
                     GAITVGGLHVRMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKYGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNVYTDKIKINAEECIVCGNCISLCPMKNLVIKNDMIISN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            13996..14749
                     /locus_tag="PC592_001390"
                     /pseudo
     CDS             13996..14749
                     /locus_tag="PC592_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            15035..15454
                     /locus_tag="PC592_001391"
     CDS             15035..15454
                     /locus_tag="PC592_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HDF4055380.1"
                     /translation="MDKISGKLTVLFEEPFWIGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDKIGYKRMQRKVKKEQEKGSIGTKAQNALKLQY
                     EERKQDRKNLAKARKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(15555..15821)
                     /locus_tag="PC592_001392"
     CDS             complement(15555..15821)
                     /locus_tag="PC592_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDF4055381.1"
                     /translation="MKKFILIYFIVINFIAFFSMYIDKERAIKHKWRIKEATLMYIAV
                     IGGSIGSMIGMYSFRHKTKHIKFTFGIPFIIFLQFLLVYFYILK"
     gene            16048..16749
                     /locus_tag="PC592_001393"
     CDS             16048..16749
                     /locus_tag="PC592_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055382.1"
                     /translation="MKFVVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDIDFRNDDVYVRFSKKGDKFVPFGETDAELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            16831..17439
                     /locus_tag="PC592_001394"
     CDS             16831..17439
                     /locus_tag="PC592_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF4055383.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSNE
                     QLKNIYLKNEEDSVDAVVLAGLHKSSKKLILIRQFRVPINDYIYELPAGLVDEGESID
                     VSVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDKFLEADE
                     EIEALLISQEEAKEILQSNHKIDTKAFLILQMFVSLGTKLFE"
     gene            17763..18227
                     /locus_tag="PC592_001395"
     CDS             17763..18227
                     /locus_tag="PC592_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HDF4055384.1"
                     /translation="MKKLVIILISIINVVSLTACKKSNESKYNNLNNKESGQTTIEME
                     LDKNYDTSDSFVNARLFCVSNDIDVLETEISFQMDGDSGIVEIKDNKTDETLWSNTWH
                     GRVDNDTFTISLANIQKEKEYAIWFTGIKINHAIVKVSFESNLVKEKEIPSK"
     gene            18615..19631
                     /gene="gap"
                     /locus_tag="PC592_001396"
     CDS             18615..19631
                     /gene="gap"
                     /locus_tag="PC592_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF4055385.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEEEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            20027..21196
                     /locus_tag="PC592_001397"
     CDS             20027..21196
                     /locus_tag="PC592_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055386.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGKEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLIV"
     gene            21577..25830
                     /locus_tag="PC592_001398"
     CDS             21577..25830
                     /locus_tag="PC592_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF4055387.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYERFGNINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGAKQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEYSIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINDIYDILPKDVKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEINNAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANIQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMLERESKNIDVKNIKVNRIQYAKNNHITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAMYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKTSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEVFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            25979..26473
                     /locus_tag="PC592_001399"
     CDS             25979..26473
                     /locus_tag="PC592_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF4055388.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDDFIVSVYIGDEKFNNLKNEYIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKNIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            26589..26966
                     /locus_tag="PC592_001400"
     CDS             26589..26966
                     /locus_tag="PC592_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF4055389.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTRAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            27173..27613
                     /locus_tag="PC592_001401"
     CDS             27173..27613
                     /locus_tag="PC592_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HDF4055390.1"
                     /translation="MDNINLLINRLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMINNENSYIRARGLLLISANAQWDIDNKIEINIDSILSHIVDKKPFVSRMFIKSIPN
                     ITKYKKNLIRRIKMELSNADISIYNNNMKPLVEKDINDTLSNLS"
     gene            28245..29552
                     /locus_tag="PC592_001402"
     CDS             28245..29552
                     /locus_tag="PC592_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055391.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKAEIGCVEEIDSEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVITIDKRY
                     DYRKELKLELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYAILVEQSKVLTDEAFDCNLASRNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    29638..29904
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            30030..30833
                     /locus_tag="PC592_001403"
     CDS             30030..30833
                     /locus_tag="PC592_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4055392.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGNTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            30871..31482
                     /locus_tag="PC592_001404"
     CDS             30871..31482
                     /locus_tag="PC592_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF4055393.1"
                     /translation="MLQGLEIVIAMFCITLIISIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRIIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            31513..32184
                     /locus_tag="PC592_001405"
     CDS             31513..32184
                     /locus_tag="PC592_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF4055394.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            32479..32841
                     /locus_tag="PC592_001406"
     CDS             32479..32841
                     /locus_tag="PC592_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDF4055395.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPNKEELKS
                     IYKTSGYDIKKFFNTSGVKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLFDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            33276..33977
                     /locus_tag="PC592_001407"
     CDS             33276..33977
                     /locus_tag="PC592_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HDF4055396.1"
                     /translation="MSIEDLYDFECVPLNNEVDIDVLFEKMIEDGKEKEYTPVIVIDE
                     KVGLLRKNIDIIIKEYGSLENYREYCLTKYNEIDVNQFFDFRKREISELLKELVDLED
                     DFYDYKHFRPIMNIDIFHEYNKIYIAKVPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKDLIKDGKKFDELCIELVFYCEDIIIQGYETLNAL
                     KDVLKRSTILLFWWD"
     gene            34286..35104
                     /gene="larE"
                     /locus_tag="PC592_001408"
     CDS             34286..35104
                     /gene="larE"
                     /locus_tag="PC592_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HDF4055397.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVVAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGIDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSGLKKEE
                     IRSLSKILGLKTFNKPSFACLASRIPYGVEITDENLRIIEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            35159..36307
                     /locus_tag="PC592_001409"
     CDS             35159..36307
                     /locus_tag="PC592_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDF4055398.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            36443..37831
                     /locus_tag="PC592_001410"
     CDS             36443..37831
                     /locus_tag="PC592_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055399.1"
                     /translation="MKVLKLITVVAMMMLFVTGCNIKTESPEQLAKIPNYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGS
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGNTGNNRNTYSSKASANIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTSTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            37860..38558
                     /locus_tag="PC592_001411"
     CDS             37860..38558
                     /locus_tag="PC592_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055400.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     ENDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALIRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            38561..39994
                     /locus_tag="PC592_001412"
     CDS             38561..39994
                     /locus_tag="PC592_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055401.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVAFQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            40016..40753
                     /gene="truA"
                     /locus_tag="PC592_001413"
     CDS             40016..40753
                     /gene="truA"
                     /locus_tag="PC592_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF4055402.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKAVEEVDERFHS
                     RYNVKSKTYMYRIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNIIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESRDRCQSSDTAPAKGLCLWKVRY"
     misc_binding    40864..41071
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            41324..42523
                     /locus_tag="PC592_001414"
     CDS             41324..42523
                     /locus_tag="PC592_001414"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDF4055403.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEIYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYETHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            42773..43819
                     /locus_tag="PC592_001415"
     CDS             42773..43819
                     /locus_tag="PC592_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055404.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNNFFFLLSGF
                     GSFCYMKTNKSELKRMVALGDGRTKKMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DSGHPVVLGALDMYYLPYYKKLYHIEHLPFHYVLMVGYDDEKVYLYDCGRTELLNLSY
                     DKLRESMNCSYPGLSKENTICTIRMNTSKNKYKIAKEVIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELSQWKTELEKDDYDKILTNMIMFFGTVPTIPNAIKGIKEPDTIQFKGGFDK
                     MSKMLKSIGEEYKNDSFIQVAEIFDKTSLIIEKISNIIVDYLTQKYDDTDQLPLLFSE
                     VLKDMKTGYLILNV"
     gene            43925..45088
                     /locus_tag="PC592_001416"
     CDS             43925..45088
                     /locus_tag="PC592_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4055405.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDDS
                     IKTLQQILFFKEIDIPLREVKEIMSSPYFDKLEALKNQRKLLILKRKRLDELIELINQ
                     TLRGEGNINFKEFDMSEYFDVLEEFKREHKSKIIKIYGSVEKYNEYIERVKFNEDKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEQHPKLKELYRKLAEDL
                     SKNPSSTELQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSKEIQSIVEEIDNEMKRSND
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGNGASKFIGEAFKIYFDNNNC"
     gene            complement(45177..45557)
                     /locus_tag="PC592_001417"
     CDS             complement(45177..45557)
                     /locus_tag="PC592_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HDF4055406.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKNNISVLEKSIE
                     NENWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EIESIKTYLGNIIESVKFDVNYIF"
     gene            complement(45560..46219)
                     /locus_tag="PC592_001418"
     CDS             complement(45560..46219)
                     /locus_tag="PC592_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDF4055407.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERVSIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(46325..47299)
                     /locus_tag="PC592_001419"
     CDS             complement(46325..47299)
                     /locus_tag="PC592_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF4055408.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGTELISIGGVLVDNEFNTI
                     DNYYSLVKPRYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDIIGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAMDLMNVCKCFFFNYPKNIDILEELYNKLPAFKTPLYYIPYFED
                     ENFELKFDRTPEDIIVYLKQILNILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKINEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(47339..47686)
                     /locus_tag="PC592_001420"
     CDS             complement(47339..47686)
                     /locus_tag="PC592_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055409.1"
                     /translation="MLNLKEIREEIIKKYIGDILISELTDELKSIIITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILLDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRIIISIDSYDD"
     gene            complement(47905..48861)
                     /locus_tag="PC592_001421"
     CDS             complement(47905..48861)
                     /locus_tag="PC592_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDF4055410.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRAKEGNPVC
                     ESGIFEILDVTDENRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EVARELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
BASE COUNT        19601 a         4924 c         8302 g        16221 t
ORIGIN      
        1 gcctgtggag aattagtaag acatatttta gtatgcaaaa ttctatgaag caggaaccct
       61 gtgactttag tcatgggagg ttcagtggag aacatttcaa caagagtata gagattattt
      121 agatttagct aagtttttac aactaatgcc tggaatagga gcatttgtag gattttatgt
      181 gaatggaaaa ttaattgata aattatgtga aactgctgtg tctgcttata gattgaggat
      241 tcgagagctt aagttataaa agttataaga gaagttataa cataaaaaat tagttataca
      301 atatatctat atacatttaa ttttgcattg ataaaaacaa ttatggataa aaggtaaagc
      361 atgatagaat ctaatgtaga ggtttgtatt ttaatggaaa aatttagttt ttaatgttta
      421 agatacaaat tggattatga agagaagtga ttgggaggaa tattttcatg acaaatttgc
      481 caaaacaatt tgatagcttt aatgaagcta gacaaaaagg atttataaat gcaaaggaac
      541 ttaaggaaag tgggaaaaag atggttggag ttttctgtac atttactcca gttgaaattc
      601 caatggcagc tggagcaact gtagtaggtg tatgcggtgt tagtgaagag ccaatacctg
      661 atgcagaaag agtgcttcca agaaatcttt gtcctttaat taaatcaagc tatgggcatg
      721 caataacaga tacctgtcca tatttctatt tttctgattt gttgatagga gaaaccactt
      781 gtgatggtaa gaaaaaaatg tatgaagaac ttgcaaaagt taagccaaca tatgtaatgc
      841 atttgccaaa tacctcaaaa ggagaatttg cctataaact ttggaaagat gaaatgataa
      901 gattaaaaga agaggttgag aaatctttag gtgtaactat aactgaagaa gatataagag
      961 ctgctataaa agataaaaat gaagaaagag aacttttaaa agaattttat gcacttggta
     1021 aattacaacc atctgcactt acaggtcttg agttacataa tgttttatat caagcaggtt
     1081 ttaaatttga ccgtgcagaa cttaaacatt ctttaagaaa agttatagat gatatgaaag
     1141 aaagatatga aaaaggagaa tgtcctgtta aaaaagataa accaagaata ttgataacag
     1201 gttctcctat tggtggaata agtgaaaaaa tagttaaaac tttagaagat gcaggggcat
     1261 cagtcgttgc atatgaactt tgtggagcta ttagatcaaa tgatttattg gttgatgaag
     1321 aaatagaaga tgtgtatgat gctttaacac aaaaatatat aaatataggt tgttcttgta
     1381 tgatgaataa tgataatcgt attgagttat tagatagaat aatagatgaa tataatgtag
     1441 atgctgtaat agatgtagtt ttacaagcat gtcatacatt taatatagaa agttatagaa
     1501 taagagagtt tgttacaaaa gaaaaaaaca agccatttat gtctcttgaa actgattatt
     1561 caaaatcaga tactgaacaa ttgagaacta gatttgaagc atttgtagag atgttgtaga
     1621 aatacataaa aataggagga attatgttta gtataggagt ggactcaggg tcagtggcaa
     1681 caaaaggtgt attgtttgat ggtgaaaaaa ttattaagaa aataattata ccaactggat
     1741 ggagccctaa aagtacatct aaacaagttt atgagttgtt aagtagtgaa attgataaaa
     1801 aagatataaa aaaagtagta ggtacaggtt atggaagagg agtaatggat tttgctgata
     1861 agaaagtaac agaaataact tgtcatacta gaggagttta ctttttaaac aataacgtaa
     1921 gaactatttt agatgtaggt ggtcaagata gtaaagttat aaatttagat agagatggaa
     1981 atgtatttaa ttttataatg aatgataagt gtgctgcagg tactgggcga tttttagaga
     2041 ttacttctaa ccttttagga agtgatatag aaagtattga tacattggct caaggacatg
     2101 agccagttaa tatatctagt atgtgtacag tttttgctga gtctgaaatt gtaagtcttc
     2161 tagctcaaaa tatttctgct ggagaggtag cagcagggat acttaaatct attgcaaata
     2221 aatccacttc aatgctagca agaggtgaga taatagatga agttgcattt acaggagggc
     2281 ttgcaaaaag taaggaatta gtgaaaatga tagaagaaat actggataaa aaaattttta
     2341 ttgcagaaga tactcaaata ataggagctt taggagctgc tgtaataggg tttagataaa
     2401 aatataaata aaataaaatg agaaactgag tttatcctaa ataaattcag ttttttattt
     2461 tattttattt atttataaag gaaaactttg gtataattga tttaaatgtt tgtatatttg
     2521 taaatacttg atatttagtc atatataaca ttagaatttt aaaaattagc tcaaaaaagg
     2581 gggagaaagc gtgaaaagat ttacttcaaa aaaagtagca aggtttgttg cactgttttt
     2641 aatatctatt ttagtaatgt caacaattcc tgcatcagct gacactagca atacattgaa
     2701 tcagataaaa aaagcagaat acagtgagac ttataaacaa tatctaaatg atgttaaaaa
     2761 tggacgtaca gaaaaatata atgggattat accaaatcca tatcaattgg aaggtactca
     2821 aattaaaagt aaaggaagaa cagctccaac atcttatgac cctagaaaat taggtcttat
     2881 gacatcagta aaaaatcaag agaatttagg aatatgttgg gattttgctg caatggcaac
     2941 tttagaaagc ttcttgaagt taaataatta tggagattac gatttatcag aagaacattt
     3001 aagatggtgg gcttcagatg gtgaatatgg atggtctgta aatgatatgg atggtgcttt
     3061 aaattatgaa gctatgggat atttaacatc ttgctcaggt cctaaattag aaaaagatat
     3121 cccgtataat ggtaaaatat ctaaagcaca aggagcaaca aaaccaacta atatgaatac
     3181 agcacctact gtttttaatg taacagatgc tgtgtgtgta agtaatgaca ttaattctac
     3241 aaaaaatgct atattacagt atggggcagt aacatctgcc tattatgaag atattaaata
     3301 tcaaagtgat gaccaaaatt catattattg tccaacaaaa agttttaata caaatcatgc
     3361 tatatcaatt gtaggctggg atgataacta ttctaaaagt aattttaatt caaatattag
     3421 accatcaaaa aatggtgctt ggctaataaa aaatagctgg ggagattata actctgaagg
     3481 tggatatttc tggatatctt atgaagacaa gacacttatg tctgatatag ataatttttc
     3541 aatcaaaggt ggtcaaaaac caagtgatga tgagaaaatg tatcaacatg actatgcaag
     3601 cattgttcct ttaatctcaa ataaaataac agcagcaaat gtattcgatt ttaatagagg
     3661 tgatgagact ctaaaatctg taatgttttt aactgaaagt ataggagcta aatatgaagt
     3721 atattatgct ccagtagtaa atggtatacc tcaagaaaat aatatgaaaa aattaaaaga
     3781 aggtactaca caatattcag gatatataac agttccaatt gattcttttg atataccaga
     3841 aggaaaaggt gcaattgtag tcagtataga ggggaaaaat ggagaatcaa ctataggctc
     3901 tgagtcaaac gtgccaggat atgatacatt taaagcaaaa gctaatttag gtgagagtta
     3961 tattatagat aatactggaa agttctttga tataaacaga gatagtaaat tctatccatg
     4021 taattttact ataaaagctg ttacagaaaa gtcttctagt gagagtgtac caaatgagtc
     4081 tttaattggt agtgatagat atgaaactgc tatcaaagtt agtcaaaatg gtttcaattc
     4141 ttcagaaaat gtagttttag taaatggagg ttcaatagta gatgcattgg cagcaactcc
     4201 ttttacatct gctataaatt caccaatatt attgacacaa aaagaagctt taaattcaaa
     4261 aactaaagtc gagatacaga gattaggcgc taagaaagta tacctaatag gtggagaaaa
     4321 ttctataagt aaagaaaccg aacaacaatt aaaaagctta aatatatcaa cagagagaat
     4381 atcaggaagt gatagataca agacaagttt attgttagct caaaagttaa atagtataaa
     4441 aaatgtatct caaatagcag ttgtaaatgg agtgaaggga ttagctgatg caattagtgt
     4501 aggtgcagca gcagcagaaa ataacatacc aatcatactt gcaaatgaaa agagtgaatt
     4561 gcaaggagct gatgaatttt taaattcatt aaatatagag aaatcttata ttattggagg
     4621 aacagcatcc ctatcaaaca atctagaaag taagttaaaa aatccaacta gattatctgg
     4681 tagtagtaga gatgaaacta attcaaagat aatagataat ttttataaaa aagatacttt
     4741 aaaaaatgta tttgtagtta aaaatggaat caagagtcaa aatgatttaa tagatggatt
     4801 ggcagtgggt cctttaggag caaaaactgg gtcaccagta gttttagttg gtgataaatt
     4861 agctgatagc caaaaagaag ttcttaagaa taagacttta gaaaaagtaa ctcaagttgg
     4921 tggaggagca aatcaaaatg catttaaaga gttagtaaaa ttaaagagtg ttaaatagga
     4981 tacttaggta ttggtatata ttaatatgta ttagtaaatt atactgataa gagctgaaaa
     5041 taattacttt aaattattga taaataagat aatcaatggt tgcaaagttt tgttttcagc
     5101 tttaaattta tgtagtataa gtttaaaaac ataaaaaagg gttactttat atagaaaatc
     5161 ttacatttta tatataaata acccatattt aattaacttt ttatagtgtt ctaatagata
     5221 ttattgaact taatggtaaa tataatgtgt aagtttcgtt taaagttgga ttagattcgt
     5281 ctatatatct tgagcaaagt gtaattgata agctgtctgc ttctataatt tcaccatata
     5341 gaggacaact gctgaagtaa gaatgtactt caacgtattt atttaaattt tcttgaacat
     5401 aatcataaaa acggttcttt gtagtagtag tcataaaatc aactccttta ttttttatta
     5461 aagctgaaac ttttaaaaag ataaatatga ttacttctat tagaaactaa gttaaaaaat
     5521 aagcaaatag atatgaaaac tagaataata tattatttat atcttaatta taacattaaa
     5581 taataaaaaa tgctatataa aattcagaat tttcgaaagt ttttaagtct atttttaaat
     5641 atactagcaa aactattgac attaaataga aaaagtaata tattgactat ataaaatatt
     5701 ttagtcaaac tggaggacgg aagatgccta aatcatattc tgacaaagaa agagagtata
     5761 taataaaaag acttaaagaa gaagcaagat tgtgtatgga gctatatggt attagaaaaa
     5821 ctactgttga tgagcttgta aaacgagtaa aaataccaaa aggaactttt tatctattct
     5881 ttcaatcaaa agagttgctt ttttttgaag tattgagaga tatacatgac tctatacaga
     5941 aagaaatctt atatgagata aatagactag ataaaagcat tacatgtgaa caattgacag
     6001 atatatttat gaaattctat aggatggttg atagtacttc aatcttaaat ctcatggtaa
     6061 atggagaatt tgagatatta gtgagaaagt tgccagatgc tataattgaa gaacatttta
     6121 gacatgatga ttttgaaatt ggagagatta tatcttgcat accaaacgca aaaaataaag
     6181 atatagaaag atttagtgga gcatttagag cagtctttct taccatgtta tataagcgtg
     6241 aggttgggag taattgtttt gaagatgctt taagattaat gataaatgga ttagttatac
     6301 aacttatgga atagaattta aattttgttt gctaataact tttattaaaa attattaaca
     6361 aacaaaaaaa ttatttttta ttgactatat agctaaaatg gtcaaaaggt tgaaagggtg
     6421 atatttaatg attaaagttg atgatttatc atttagttat acagataaaa attttttaca
     6481 aaatattaat tttgaagtag gaaaaggtga aatactaggt tttttaggtc catcaggtgc
     6541 aggaaaatct acattacaaa agattctaat tggaatgata actaattata aaggaagtgt
     6601 cattgtaaat ggagtagaga gtaaaaggca ctcaaataaa ttttatgaaa atataggagt
     6661 tgattttgaa tttcctagtt tatatgaaaa gttgactgca atagaaaatt taaaatattt
     6721 tgggtctcta tattctaaaa aattactatc tattgataag ttattaaaat cagtagggct
     6781 agaaaataaa gcaaataaaa gggtatctga gtattcaaaa ggtatgaaat ctagattaaa
     6841 ctttataaaa gctttattac ataatccaga tattttattt ttagatgaac caacaagtgg
     6901 tcttgaccca tcaaatagca aggttatgaa agatataatt ttatcagaaa aatctaaagg
     6961 taaaactatt attttaacaa ctcataacat gttagatgca acagagcttt gtgacagagt
     7021 agcattcata gtaaatggta aaatatctgc tttagataca ccacataatc ttattatgtc
     7081 aaaaggagct attaaagtta aatatactta ctttgataat ggagaaaaaa cttctgaatg
     7141 ttttctgaat aatactgcta atgataaaaa tttgaatatg cttattgaga aaaataaact
     7201 tttatcaata catagtagtg aaccaacatt aaatgatatt tttattgaga taacagggag
     7261 gaatttacaa tgaggctaaa aaatcttgtt ttaggagata taaagtttca atttaaatat
     7321 ggtttttatt ttttatatct ttttttaagt attatatata tttgtattat caatgtattt
     7381 ccaactttta tgagagaaaa aatagctata attatgattt attctgaccc agcagcaatg
     7441 ggattgtttt ttatgggagc tattgtactt cttgagaaaa gtcaaagggt tttaaattcc
     7501 ttagctgtat ctccagtaaa agtatctgag tatattttat caaaggtaat ttcattagga
     7561 gtaatatcta gtattgtagc tatgcttatt gctattacat taaatttaga taatattata
     7621 atatcaacta tagggacttt tttttcttct attatatttt ctttgcttgg attgatactt
     7681 gcaagtaaag catctagttt gaatcagttt attgttttaa gtattcctat tgagattata
     7741 tgctttattc caccaatact caatgtactt gttgatacaa aatcatatgc aaatttttat
     7801 ccttttaata tatgtatttc tcttattagt ggagataaaa attttatagt gattaatatt
     7861 ttaattttaa tatcaatgat aataataatt tattttataa cttattattt tatttgtagt
     7921 agttggaaaa aggtaggtgg agtaaaacta tgataaagat tataaatgcg tttaaacaag
     7981 agtttgaaca aattaaaaga gacgctatgc tttttatagt atgtgtctct ccaatattat
     8041 gtggagtatt tataaaattt ggaataccct taatacagaa tatatcactt aacaagtttt
     8101 attatcaatt aaatttagaa ccgtatttat tgatgtttga tttactttta gcttttatta
     8161 caccttttat gttctttttt gcttctacaa tggtcgtatt gggagaaatt gatgatagta
     8221 tttcaaggta tttaatagta actccgcttg gcaaaactgg ttatcttgtt tcacgatttg
     8281 gaataccagg tatcttagca tttattatta ctatgattct acttatcttt ttttctctaa
     8341 ctagaatttc ttttttgtta aacttatcaa tttctttatt agttttatta caaagcgtta
     8401 ttatatcaat attagtgatt tctttatcat caaataaact agaaggaatg gtaattacga
     8461 aattctcagg tgtttttatg atgggtattt tagcaccatt ttttatttta aataaagtgc
     8521 aatatattct gttcttctta ccaacttttt ggctatcaaa ggcatttaag gaagataatt
     8581 atatctatat gtttatttcc attattatat cattaatatg gattttacta ctatttaaaa
     8641 agtttagtaa aaaaatagtt aaataagaca atttaatata taaatgtaag gttgacttga
     8701 cagtaaaatt gaaaaatgtt acatttaaaa tgtaaggtta acattacatg aatggagcaa
     8761 atatgaaaaa taaaataaag atattaagag aaaaattagg attgacacaa gaacaactag
     8821 gaagattagt tggaacatct agacaggcta taaatgctat agaaactggt aaaaatgaac
     8881 cttcaatatg gttggcatat gatatttcaa gaatttttaa tgaaccaatt gaaagtgtat
     8941 ttttatttga agaaagtgaa agaaaatcaa gagcacagat aagtagggga gaatattatg
     9001 gctataagaa agataagaac atttgatgat gaaattttaa gaaaaaagag taagtatgta
     9061 gaaaacgtag ataataagat aagagaaata ttaaatgaca tggcagagac catgtataat
     9121 actccaaatg gaggaggatt agctgcatgc caagtaggag tattaaagcg actagttgtt
     9181 atagatttag gagaaggact tattaagctt gttaatcctg aaattattaa acaagaaggg
     9241 gaacaaattg ttgttgaagg atgtttaagt tttcctgaag tatggggtaa attaaaaaga
     9301 ccaaaaaaag ttacagtgca agctctaaac gaatacggcg agaaaataga aattaaaggt
     9361 tcaggtttta tggcaaaatg tctttgtcat gagatagacc atttaaatgg tatagttttt
     9421 acagataaaa ttattgaaca tgtaaaattg taagatagat aagatagatt ggttattgaa
     9481 tttataaaat attttatagt aaggagttaa attatgagat tatggcataa agatttaatt
     9541 gatgtattac ctaaaaatca attagtaagt caatggagag agctacttgc tataaaaggt
     9601 tctatagata aaaaaggtac tccaaaccat atattagtga ataaagtgtt gaattatagt
     9661 atagatgaat ttaaatttta tacaaaaatt gtacatgatg aaatgttaaa aagaaattat
     9721 aaacctaatg aacttaaata tacaggtata ttaaaatgga aaaatagaaa ttttgcaaat
     9781 gatatatcta atgaacatag tttagattta gaaaatttat atgatggttg gcacaataaa
     9841 atgtatttaa agcaatgctt atataattta gaagaaaaag caacatgtgg aggaataccc
     9901 ataaatgaat ggaatatatt actttgtaaa tatagtaaag attatgaatt gtggtatgga
     9961 aatatcatgt tttaattact atagattaac attataatat tattgtatat aaagaggtga
    10021 ttatttgtat aataaaataa aatatattcc aataaattgt gaaatagctt gtaataaact
    10081 aaaaaggagt atgccatata aatgggattt gaatatttat cgtggatgtg agcatgggtg
    10141 taaatactgc tatgctattt actctcataa gtatatcaac tccaataatt attttgaaga
    10201 aatttatgta aaaacaaata tagtggaaaa gcttgagaga caacttaaaa gcagtaaatg
    10261 gaagaaagaa gtaatcaata taggaggagt tacagatagt tatcaaccaa tagaagctga
    10321 ctataaaatt atgccagaaa tattaaattt gctgataaag tacaagacac cagctattat
    10381 ttctacaaaa tcagatttaa tcttaagaga ttacgattta attgataagc tatctaggat
    10441 tacatatatc aatgtagcat ctacaattac cacagtaaat gaagatacac aaaggcttat
    10501 tgagccaaat ggtgtggatt caattagacg atttaaaatg ttaaaagaat ttagaaaaac
    10561 taacgcatca gttggtctac atattatgcc aattatacca tatattacag atgattttga
    10621 taatataaat ttgctattta gacatgcaaa agaatgtaat gtacattatg ttttacctgg
    10681 gactttatac ttaaggggta taactagagg tatttttttt gactttgtta aaaaagagtt
    10741 tcctgaatta tttgataaat tatcaatact atatagcaca ggttcactta atagggggta
    10801 taaaaatcaa ttgtataaaa tggttaatga acttagatat aaatattctc tatcaagcag
    10861 ttactctaaa ataatgaaag aaaagttaaa aaactcagga gatgtacaga tatctttttt
    10921 tgattagttt tatataaaaa aattttttca ctatgatgat taaaatttat taaaattaaa
    10981 atttattgac aagtattaaa tttaaatata caattaattc ataaaataaa aatatgaaag
    11041 gatgatgttg ttcagtgata cttgatatta taaaatcatt gatataagta ttgctggaaa
    11101 agagtgaata aaatcaaatt taataagcaa acaaagtaaa gctatagttt tattgttgtg
    11161 cttaaaaata tttgattcta ttttactctt atttaaactc atctttttga agttaaatca
    11221 cagagtaaac tctgtgattt ttttatttta aaaataaatt ttaaggagtg gtatgttttg
    11281 ttaaacaaat tatgtatgta tttagaaaga ccagagcttt ataaacaaag tgaaattaat
    11341 ttttgggatg atgagtatat ttcaaagcaa ttattaaaag cacacttaga cactaatttt
    11401 gaaggagcaa gtagaaattt taactttatc gaggattctg taaattggat agttacagtt
    11461 gcaaatccag ttaagtatcc taaattactt gatttaggtt gtggcccagg tttatatgca
    11521 gagaaatttg cacaaaaagg ttataaggta actggaattg atttctcaaa acgttctatt
    11581 aactatgcac aaaatagaaa taaggagact aatttaaaca taaattactt gtttcaaagt
    11641 tatttaaata tgaattataa tgaggaattt gatttggcta ctttaattta ttgtgattat
    11701 ggagctttgt caactgaaaa tagaaggttg ttaatggaaa aaatttatga tagtttaaaa
    11761 cctggaggaa aattaatatt agatgtattt acaataaata aatacaataa ttttgaggaa
    11821 attaaatatt gggaaataaa tgaagatgga ggattttgga gtaatgaaaa atatatgtgt
    11881 ctacaagata attgtaaata caatgattat aatacattag aacaaactct tgtaataaca
    11941 gaaaaagatg aaaatgtgtt ttatgtttgg aatcactatt tttcaaaaga aagtttctta
    12001 ttcgaaattg aaaatattgg atttaagtct gttgagtttt ttagtaatgt taaaggtgaa
    12061 gcatattctg acgatagtat gactatggga ttagttttac aaaaataata atttttttaa
    12121 aatgaataaa taaaaacttg aaacctctaa taataaaata aaataagaaa agcttacata
    12181 ttgaaaaatg gaaactttta tgttattttt aatacattac aaatttgctt atataaaaat
    12241 caacacttaa attattattt ttatatgaaa tttatctata gtatattttt ataaacaagt
    12301 aatgctatta aaattaagta tatagtcaaa agtgtatagc aaaaaggctg ttatattaat
    12361 gttagaggtt cagggaaaat atataaagca aagatattta cagataatgc aaatggtaca
    12421 actataagtt agataataga attatgtaat caagaattta caacaaagtc taagataagg
    12481 ataataccaa attgccatac aggtgctaga tgtgtaaatg aattaaatta atactattga
    12541 taaagtacaa caagcacata aactaattga tgagattatt aaaactataa gagatatagt
    12601 tgacataatt aaaatattgt aatctattta taattttatt ataaatcaat aatgattaag
    12661 attgaaataa tattaaggca tcaatgttat aagtttacaa tataaggagt actatatagt
    12721 attccttact tacacatatt aggcaatagg aagttttttc atagttaagt tttcaaatat
    12781 tttttaggga actttgtaat tgagaattaa gggtatagta tgtgatgaac ttactaaatt
    12841 tataattagg ttatataatg gaataatcat caatagtttt actttaggga aaatacatgc
    12901 ttaaggaagt atagcttact aatattatta aaatgtatat ttaaaatgat aaaaaaagaa
    12961 ttagacaagt agttagtaaa ttgattatgc aaaattctat caagcaggaa ccctataact
    13021 ttagtcatgg aaggttcagt aggtaatctg ttgaattaag tttatattat ttaaataaac
    13081 tacttaattt agataataca aaaagtcaga attttaagaa tagagctata taatcttagc
    13141 tattaggaga attactatga taggaatata ttttagtgga acaggaaatt caagatattg
    13201 tgtagaaaaa tttttacaag aatatgatat aacagcaaat tcttattcta ttgaagataa
    13261 tgaactttta cagtgtatta ataatcatga gaatattatt tttagttatc ctgtacaata
    13321 tagcaatgta ccaaaaatat tgaaagattt cataataaat cattcaactt tgtggagtgg
    13381 taaacgtgtt tttattattg caactatggc tctatttagt ggggatggct ctggtgtgtt
    13441 atctagaatg ttaaaaaaat atggtgctat aactgttggt ggattacatg tgaggatgcc
    13501 agatagtata ggagatgaaa aggtattaaa acattcttta gagtataata gaaagcttgt
    13561 aataaaagca gaaaagaaag taactaaggc tgctaaaaaa ttgaaatatg gatcaccacc
    13621 aaaagaaggg ttaggttttt tgagccatat tgtaggatta tttggacaac gattgtattt
    13681 tatcaataaa acaaacgtgt atacggacaa gataaaaatt aatgctgagg aatgtattgt
    13741 atgtggtaac tgtattagtt tatgtccaat gaagaatcta gtaattaaaa atgatatgat
    13801 tatttcaaat ggtcaatgta caatgtgcta tcgttgtgta aataattgtg ctaaaaaagc
    13861 aattacattg ttaggtaaaa aggttgttga acagagtaat attaaaaaat acatgtaaga
    13921 actttaaaat tttactaaat atacattgat gtatacttta tgttagaaag agagctcaaa
    13981 taatggaata ctaccataat tgattcattt gcaactaaat tatttaaagg aaatactgct
    14041 ggaatttgtg ttcttggcag aagaatacct ttagagttaa tacagaaaat agcagaagaa
    14101 aacaatttac cagaaacggc atttgtagtt aaagataaaa ggaattatga attatgatgg
    14161 tttactccta aagtagagat tgatttatgt ggtcatgcaa ttttagcagc tgcttatgta
    14221 atatcaaatt ttattgatgt taatgtaaaa aagatagatt tccttactca aagtggaaag
    14281 cttgaaatta cacgaaatga tatttccaga aataatgttt atcggaatag agttatcacc
    14341 acaacaaact aatttgatag gctgtgtacc aattgctgtt tattcttcaa gagatttaat
    14401 tttattgcta aacagtgaac aagaagttat aaattataaa cctaattaca cacagctgag
    14461 taaattgaca gactggttag gtataataat cacagctcaa ggaagtaata cagattttgt
    14521 atcaagatat ttttgtccag aattagattc aggaaaccct gttactggtt cattgcattg
    14581 taatcttatt ccatactggt ctgaaaaggt ggaaaaacgc aaaatggtag ctgctcaact
    14641 ttctaatcgt ggtggtataa ttcagtgtaa attattaagg gataatactg taaaaatttc
    14701 tggtaaagta gtcttgttta ttcaggtaac aataaagatt gacatttaaa gaagtataat
    14761 aactaattta taatttaatt tactatgaat tatgaaaaat aattaatttt cttagagtta
    14821 attataataa agtagagtga aaaaatttaa tttcatttaa agcaatatga tagacgttga
    14881 tactaagatt gacaagcatg attaaaaaag atagtattta atctataaag ataaaaacac
    14941 agtctggttg gtagtccaga cgcagcaata gctgtaagta acctgcctcc ttggttgtcc
    15001 attctttaga aagtaattta aggaggaact agcaatggac aaaattagtg gaaaattaac
    15061 agtcttattt gaagaaccat tttggatagg catatttgaa agacaagatg gtaaaaaata
    15121 tgaagcatgt agggtagttt ttggggcaga gcctaaagag gtagaagtat atgaatttat
    15181 acttgaaaga tttttctcat tagattttgg cagtattaag ttagaaaaaa atgtgactaa
    15241 agacaaaatt ggatataaaa gaatgcagag aaaagtaaaa aaggaacaag aaaaaggatc
    15301 tatagggact aaggctcaaa atgctcttaa gcttcaatat gaagaaagaa aacaggatag
    15361 aaaaaaccta gctaaagcta gaaaagaaga agaaaaagaa agacttttta atttgaaaca
    15421 agaaaagaga aaagctaaac ataaaggtca ttaattttaa ttggctttct ttttaataat
    15481 tgcttgaaaa ggtgtataga atcaaaaact ttatacacct taatttattg aaaaaataaa
    15541 gctttatatt tcaattactt taaaatataa aaatatacta ataaaaattg taaaaatatt
    15601 ataaatggta taccaaatgt aaatttaata tgtttagtct tatgtctgaa agaatacatt
    15661 ccaatcatag aacctatact gcctccaatt actgctatat acataagagt agcttctttt
    15721 attctccatt tgtgtttaat tgctctttcc ttatctatgt acattgaaaa gaaagcaata
    15781 aaattaataa ctataaaata tattaaaata aattttttca tagtcttgcc tccataaaaa
    15841 tatattatac attataaaat aagatatttg ttttggaaag ttaattttgc aattagtaca
    15901 tataaaatac ttgataagaa ttaatataat attaattgga aaatttaaaa aaattaaaca
    15961 attagcaaat agggggtata tttataagag acaaagtgat aaaatttact tagaaaataa
    16021 tgtaaaataa caggaggata agacaaaatg aaattcgtag tggaaaaaga agtctttgat
    16081 aaattagaaa atgtatgctt tggtgtagta gtagcaaaag gcatagataa cactaaagaa
    16141 atcgaaagaa taagcaatct tttagatata agtatagata gagtagaaga ttacttcaaa
    16201 gataaaaaag taaaggaatc agaagaaatt ataccatata gagaggcatt tagaagtcta
    16261 ggtatgaacc caaataaatt tatgagttca atagaagcaa tgacaacaag agttgctaag
    16321 aataagaaac ttcctcatat aaatcctatc gtagatttag gaaactctat ttctttaaaa
    16381 tatttacttc caatgggtgc tcatgatata gattttagaa atgatgatgt atatgttaga
    16441 ttttctaaaa aaggggataa atttgtacca tttggagaaa ctgatgctga gttaatggaa
    16501 gaaggagaat taatttattc agttggagac atggtaaaaa ctagaagatg gatatggaga
    16561 caaggagagg aagggaaaat tactaatagc tcaaaaaata tattttttcc tatagatggt
    16621 tttactgatg ctaatttaga taaggtaatg agtgcaagag aagaattagc aaaattgtta
    16681 aaggaaatat ttaattgtga aattaaagta ggttttgtag ataaagataa tcctgaaatg
    16741 gaaatataat aagttgttga atatttgtta agatattata tttacttaat gatgttaaaa
    16801 aggtattaaa aaagaaaggt cgtagtaaat ttgaaaaaaa ctataataaa gaatgtaaat
    16861 ccaatgattg aaaataagtt tataggactt tttgaaatag agtataaaaa caaactagat
    16921 gaagataagg tttggatggt agcatcaaga aaaagtaacg agcaattaaa aaatatttat
    16981 ttgaagaatg aagaagatag tgtagatgca gttgtattag ctgggcttca taaaagtagt
    17041 aaaaaattaa ttttaataag acaatttaga gtacctatta atgattatat atacgaatta
    17101 ccagcaggtc ttgttgatga aggagagtct atagatgttt ctgttgaaag agaacttaga
    17161 gaagaaacag ggcttactct tttagaaatt aaaaaaaata aaagtattga taaagtgtat
    17221 ctatctcctg gaatgagtga tgaatctgtt gcctttgttt attgtatatg tgatggggat
    17281 ataacagata aatttttaga agcagatgaa gagattgagg ctcttttaat ttctcaagaa
    17341 gaggcaaaag agattttaca aagtaatcat aagatagaca caaaagcatt tttgattttg
    17401 caaatgtttg tgagcttagg aactaaatta tttgaataga tatatggaaa agaggttata
    17461 tagagaagta aaataataaa gtttatttta cttttctaaa ttataatctc tttttttata
    17521 caataaagta taattttgtg tatttttaaa taagtgactt gactcttaaa ttttcataat
    17581 atgttataaa ccaattttag atactgcaat aattaaaatc caaaaattat ttaacatatt
    17641 tgcaattaaa atgagaaaag gtaaagactg aatgattgaa aaatttgatg tgaaatagct
    17701 gattagttta atattatagt ttgtagggtt aaaaattaga aattgtaaag gagataaatt
    17761 ctatgaaaaa attagttatt attttaatta gtatcattaa tgtggttagc ttgacagctt
    17821 gtaaaaaaag caatgaaagt aaatataata atctaaacaa caaagaatca ggacaaacaa
    17881 ccattgaaat ggaattagat aaaaattacg atacttcaga ctcatttgtt aatgcacgtt
    17941 tgttttgtgt gtctaatgat atagatgttt tagaaacaga aatttctttt caaatggatg
    18001 gagatagtgg cattgtagaa ataaaagata ataaaacaga tgaaacttta tggagtaata
    18061 catggcatgg aagagttgat aatgatacat tcacaatttc tcttgctaat atacaaaagg
    18121 agaaagagta tgctatatgg tttactggaa ttaaaataaa tcatgcaatt gtaaaggtta
    18181 gttttgaaag caatttggtt aaggagaaag aaataccctc aaaataaatt ccagtttgtt
    18241 tataacttaa tattcagtac ataaaagcag ttaatattta tgattgactg ctttttctta
    18301 tttaaaaagg atgagctgtg catttttaat tgaaatagtt catacacatt aaaaattggt
    18361 gaatatatta ctggagaagg atggcaaaat atgtcccaag ggacattgag caaaataaat
    18421 gacttcagct tctctgtgct aaaaagtata tactaaataa gggttaaagt agataaaaat
    18481 gatacactaa ttgtcttttg ataataaaaa aacatgaaat ttaattattt aatcaagaaa
    18541 aagtattgaa taaatgattt atttagtgta caataatcat gtaaaaacat agtaatggag
    18601 ggagacattt cataatgaaa attaaggtag gaatgaacgg atttggaaga ataggaagag
    18661 ctgtattaag aatagctcaa gaagaattag gagataatat agaaattgta gccataaatg
    18721 caagagcaac aacagagtct ttggcacatc tatttacata tgattcatgc tatggaactt
    18781 ttagaggtga agtagaagca aaggatgaag acacactagt agtaaactct aaagaaataa
    18841 aaatattaag atataatgac ccagaagaat taccatggaa agaattggga gttgatatag
    18901 taatagaatc aacaggattg tttacacaaa gagaaaaggc agaaaagcat attaaagcag
    18961 gagcaaaaaa agtaattata acagccccag gaaaaaatga agatataact atagttatcg
    19021 gagtgaatga ggaagaatat gataatgaaa agcacaatat aatttcaaat gcatcttgta
    19081 ctacaaattg tctagctcct tttgctaaag tattggacga aaaatttggt atagtaaaag
    19141 ggttaatgac tacagtacat tcatatacta acgatcaaag aatattagat aaaagccata
    19201 aagatttgag aagagcaaga gcggcggctg aatctataat acctaccact acaggagcag
    19261 caaaagctgt gtcaagagta ttaccacaat tagaaggaaa attaaatggt ttttcactta
    19321 gagtgccaac accaacagtt tcacttgttg atttagtatg cgaacttaaa gaaaacgtta
    19381 catctgaaca agttaactct gtgttaaaag atgctgctga aggagaatta aaaggtgttt
    19441 taggatattg tgacaagcca cttgtttcta tagattataa aggagattca agatcatcta
    19501 ttatagacgc tctatccaca atggttatag aagacaatat ggttaaggta gtttcttggt
    19561 atgataatga atggggatat tcttcaagaa ctgttgattt agtaaaatat gtagctgaaa
    19621 aattaaaata gtatataatt cttagaataa attaaaaaaa attttttgaa aaaaattgta
    19681 taaaactaaa aaaaagatta tgaaaaatat tgaaggaaaa attttttcat aatctttttt
    19741 ctttcatgca aaagatacaa gttacaactt atatttgtat attaggtcgt tagagaagta
    19801 tatatatatt tagtaaggaa tcgtactttt tataaaatga aagataagat gtcgaaaact
    19861 tgcataaatc tgaaaaattt ttattattaa aatactgatt ttcattttaa atgtgataaa
    19921 aaaatgacaa ataaagttgc aaatagtaat acttataagt ataattaaaa aagagaaaag
    19981 gttttgttaa actttataac aaaagaaaaa gaagggatga ttcaaaatgg agaagttaac
    20041 agacaggaga caggttaagg cagtaagcat ggaaaccttc attttcctaa tattactagt
    20101 agttggtttt gggtatgttg gtagtattat gggtgcagga atgatgttca aagtaataat
    20161 gagtacggca catgctttac tattagagac agttttctta attatggcta tggcggttct
    20221 tgcaggcgca ttaagcgcac tactttcaga gtttggagta atagcgttaa ttaataaaat
    20281 tttcgctgta tttatgaagc ctttatatgg gctacctggt gctagtatag caggagctat
    20341 aacaacttat ttatcagata atccagctat tatacctttt gctaaagata aaacattcac
    20401 acagtatttt aaacaatacc aagttccagc attatgtaac ttaggaacag cctttggtat
    20461 gggacttatc ttaacaacat ttatgatttc tcaaggtaca gaatatgtac ttccagcatt
    20521 aattggtaat ttaggtgcaa ttataggtag tgtcataagt gttagaataa tgttgacatt
    20581 tactaagaag ttttataaat acaatccgga agaagataaa gcaacaggaa cattagagaa
    20641 aaaggatgaa tttagagaaa tcagagaagg taatgtattt caaagagctt tagatgcaat
    20701 tcttgaaggt ggtaaaatgg gagtagatat gggaatggct ataatcccag gagtcctagt
    20761 agtatgtaca ttggtaatgt tattaacttt tggaccatct acagaccctg ttacaggtaa
    20821 agaagtttat acaggagctg catatgaagg aataaaatta cttccagtta ttggagacaa
    20881 acttggattt atattagaac cattatttgg atttacatca ccagaggcaa tagcattccc
    20941 tataacttca ttgggagctg ttggtgcagc aatgtctcta gttccagagt ttataaagtc
    21001 aggagctata actcctaatg atatagcagt atttacagct atgggtatgt gttggagtgg
    21061 atatttaagt acacacattg gtatgatgga tgcattaaat gctagacagt tggcaggtaa
    21121 agctattctt tctcatacaa taggtggttt atgtgcagga gcagcagctc actttatatt
    21181 tacactcata gtataaatgt aatcagctaa aataaaaaat aatatacaaa aaaatggttg
    21241 ttgatatgta ataagaattt gcatatcaac aaccattttt ttctggctaa agataattta
    21301 taatacgtaa acattaagtg gatattagag ttaagttata tttatgtaaa aagtaacaaa
    21361 aatctgtaga aatttatgac aaaatttagt acactaacta tatgttctta tttaaaattt
    21421 gaggttagaa ttaggaatta cctagtagag taagatttga ttaataaaag aatcataaaa
    21481 taaaaatatt agtcataaac attataaata acttacttaa aataaagcca tagaacttac
    21541 aaaaattaaa aaagcatata aatatggagg ggtacaatgg atgaattatt tcatatagga
    21601 attgatgtag gttctacaac ggtgaaggtt gtggtactta ataatagtaa taatatagtt
    21661 cataaagaat atagaagaca ctattctgat gtgaaaaaat cagttaaaga agtactaaat
    21721 ggtatatatg aaagatttgg aaacataaat actaccatta taataactgg ttcaggtgga
    21781 attggaatat caaaaaaatt aggcgtaaaa tttgttcagg aagttatatc tagtacaaaa
    21841 tcaatagagt atttccatcc tgaaactgat gttgtcatag aacttggagg agaagatgca
    21901 aaaataacat atctaagtgg aggaatagac caaagaatga atggaatatg tgcaggtggc
    21961 actggagcat tcatagacca aatggcatca cttttaaaga ctgatgccag tggattaaat
    22021 gaacttgcta aagggtataa tgttatatat cctatagctt caagatgtgg tgtttttgct
    22081 aaaacagata ttcaacctct tataaatgat ggagctaagc aaactgatat agcaatgagt
    22141 attttcaatg cagttgtcgt acaaactgtg agtgttctct cttgtggaag aaaaatagaa
    22201 ggaaatgttg cgtttttagg tggtccatta tattttttat ctgaacttag agaagcattt
    22261 aaaagagttt tggatttaaa agatgaaaat ataatcttcc cagaaaatgc acagctttat
    22321 attgctattg gagcaggatt attatcagta gatgagtata gtatacaact aaaatctcta
    22381 atagaaaaat tggatagtat aaagaatatt gaagatggag aagtaaattt attagaacct
    22441 ttgtttaaag acaaaaatga gtatgaagaa ttttcaagaa gacatgaaaa ggaaaaaata
    22501 aattatgtgg acataaattc aataaagagt aattgttatt tgggaattga tgcaggctca
    22561 actacaacta aagcagcact tattgatgaa gatggaagac ttgtatattc ttattacaat
    22621 agcaatgaag gaaatccatt aaaaacaacc attaaagtca taaatgatat atatgacata
    22681 ttaccaaaag atgttaaaat attgagttca actgtaactg gatacggaga aggtcttatt
    22741 aaaaaggctc ttaaaatcga taatggagag atagagacta tagcacatta caaagctgct
    22801 aaatttttca ataaagatgt agattttata cttgatattg gtggtcaaga tatgaagtgc
    22861 ctaaaaataa aagatggagt aattgataat ataatattaa atgaggcttg ttcatcaggt
    22921 tgtggctcat ttttagagac atttgcaagt tctttatcta tgacaataga agaatttgca
    22981 catgaaggta tttattctca aaatcctgta gatttaggtt caagatgtac tgtatttatg
    23041 aactctagag taaaacaagc tcaaaaagaa ggtgcaagtg ttggagatat atcagcgggg
    23101 ctatcttatt cagtaataaa aaatgcctta tttaaagtaa taaagattag agatttaaat
    23161 gagattggta ataatattgt tgtacaaggt ggaacctttt ataatgattt agtgcttaga
    23221 agctttgaaa aactaattgg gaaaaatgta attagaccta atatttcagg aattatggga
    23281 gcttttggtt cagcacttat agcaaaagaa aaatatgaaa gtggatacaa aacatccttg
    23341 ttatctaagg aagagttgaa taatatcaaa ttagaagcaa gtgtaactag atgtaaaggg
    23401 tgttcaaatc attgtcttct tacaataaac aaattttctg ataatgaaat ttttatttca
    23461 ggtaatagat gtgagaaagg tgaagctatt tatggcgata aaaaaatagg gttagaaaag
    23521 aaaaaaccaa taaatttatt taagtacaaa tataatagga tttttagata caaaccattg
    23581 gaaaaagaag aagcaaaaaa tggggaaata gggataccaa gagtattaaa tatgtatgaa
    23641 gattatccat tttggttcac ttttttcaat gctatgggct ttagagttgt actttcagat
    23701 aggtcatcaa aacagttata tgaaactggt ataactagta ttgcatctga aacagtttgt
    23761 tatccaggaa aattagttca tggacatata gaaaatttaa ttgcaaaggg aataaaaaat
    23821 atattttatc caagtgtaac aaatgaaaat aaagaggatt caaatgcaga taattattat
    23881 aattgtcctg tagtaatatc atattctgaa gtaataaaaa ataacgtaga gaatataaga
    23941 aataagaaca taaactatat aaatccattt ataagtctaa atgataagga aaaattgaag
    24001 aaaagactat atgatgagtt atcaagacat ttttccgata taaaaataac taaagaagaa
    24061 attaataatg cagttgataa agctactgat gaacagaatt tatttaaaat ggagatacaa
    24121 gcagcaggtg aaagagcact taaagaaata aaagaaagaa atatgaaggg tattgtgtta
    24181 tgtggaagac catatcatat agacccagaa ataaatcatg gaatgccaga gcttataaat
    24241 tcattagata tggcagtgct tactgaagat tctatatgtc acttagccaa tatacaaaga
    24301 ccacttagag ttgtagacca atgggtatat cattcaagat tgtataaagc agccagtttt
    24361 gtaagagata aaaactattt ggaacttgtt caacttaatt catttggctg tgggttagat
    24421 gcagtaacta cagaccaggt tcaagaaata cttaatgaaa aatcgaagat atatactatt
    24481 ataaagattg atgaaggcaa caatttagga gcagctaaaa taaggatgag gtctttaaaa
    24541 gcagctatgc ttgagagaga aagcaaaaac atagatgtaa aaaatataaa agtaaatagg
    24601 atacagtatg ctaaaaataa tcatataacg aacaaacata ctatattagc accacaaatg
    24661 tctccaatac attttcaatt ccttgaaaaa gctgttaact taagtggtta taatatagaa
    24721 attctaaaag atactgatag tagtgtaatt gaagaagggt taagatatgt aaataatgat
    24781 gcatgttatc cagctataat agtagtaggt cagctaataa cagcattaaa atctggcaaa
    24841 tatgatttaa ataatacttc tgttactata actcagactg gtggaggttg tagagccaca
    24901 aattatattg gattcttaag aaaggctatg tatgatgctg gatttaaaga tgttcctgtc
    24961 attgcactta gtgtaaatgg aatagaagat agtggtataa tggacaatat atcactaaaa
    25021 ttaatcaata gactctttat gtctgttgtt tatggtgatt tgctgatgaa agtactatat
    25081 agagtaagac catatgaaaa agttactgga agtgcaaatg ctctatatga aaaatgggtt
    25141 gatatatgca aaacttctct tgttaaagca aaaatttctg tatttaccag aaatataaaa
    25201 gatatagtaa aagaatttga taatttagag atactagata tcaaaaaacc aaaagtaggt
    25261 ttggttggag aaatattggt gaaattccat ccaattgcaa ataataattt agtagatata
    25321 ttagagcgag aaggtgctga agcagtcgta ccagacctta caaatttctt cttaagttgt
    25381 gcctttaata ctatatacaa acacactcat ttagaaggaa gtagaaagag tagaatgata
    25441 ggagaagtat ttatatacat aactggaata tatcaaagag tatataaaaa agcacttgat
    25501 aagagtgaga gattttatgc tccagccaat ataaaaaatg ttgctaaaag tacagaacca
    25561 gtagtgtcat taggtaatca aaccggagaa ggttggcttt taacaggtga gatggttgaa
    25621 ttattaaatg aaggtgtaga aaacattatt tgtatgcaac cttttggatg tttacctaat
    25681 cacataattg gtaagggttc tataaaagaa ttaaagaggt tgtataaaaa tgcaaatata
    25741 atacctattg attatgaccc ttctgcaagt gaggtaaatc aacttaacag gataaaactt
    25801 atgctttcta aggcttttaa aaatatataa gatttatatt ttaatatgtt aaaagttaat
    25861 gaatttaaaa atatactcta tattaagtat ctataaaaaa gagttatcct attttttagg
    25921 gtaactcttt attagttaaa aaattatatg tatactgata ttaaaggggg gaagtaatat
    25981 gagtttagta tatgatgttt ataaatcaaa attaggaaat ttgtacatat taagtgaaga
    26041 tgattttata gttagtgtat acataggaga tgaaaaattt aataatttaa aaaatgaata
    26101 tattaaaaaa ggaattgata taaagagaag taaggaagat ttaaaggaag caataagtca
    26161 gatagatgat tactttaatg gaaaaagaaa agtctttaat ttaaatattc gtattgaagg
    26221 gactgaattt caaaaatcag tttataggga aatgttaaaa ataccttatg gagaaacatt
    26281 gtgttattca gatatagcaa gaaatataaa taatccaaaa tcagtaagag caataggaca
    26341 agcaagtaaa agtaataaaa ttccaataat aataccttgt catagagtag ttggcaaaaa
    26401 aaatattggt ggatatatgg ggaatcattc tgatttgaaa gagatactat taaatttaga
    26461 aagacagagt taacttagaa agaaatgttt ttattgttaa tatttgatat aataatatta
    26521 aaaataagta ttttttacaa aaacaataaa gaatttattt taatttacaa aaatgagggg
    26581 gaattttaat gtgtgataaa gttatagcat caaaatatca tgagaaggga tttaattgtg
    26641 cagaatcagt tataaaagca tataatgaag aatttaatac agatatacca gtttgcctag
    26701 gtagtggact gggttcgggt tgtggagttg ctagtttatg tggtgcagta aatgcatcaa
    26761 atataataat tggatacgta aaaggcagaa accatgaaga tgaaagtact agagctaaag
    26821 tatatgctaa agatttaact acaacagtaa gaaaagagta tggttcagag ttatgtatag
    26881 acctaaaaaa agatttagtt gcctgtagag aaataatgga tttcgcatat gatagtctaa
    26941 aggaaacttt aaaaaaagaa ttataagaaa ataagctatc aagtacaaat tatttgatag
    27001 cttattttta tagtctatac taaataaatt aaacatattt tagaattatt atttgtaaat
    27061 aaacatcaaa taattttagg ttttttattt aatatagctt tttatttata tttgtttttg
    27121 aatgtgttat actctgttta aataaatatt tgtaataagg gagatgagaa gattggataa
    27181 tatcaatttg cttattaata gattatattc aaaaaatcat aatgaagcat ataaaacttt
    27241 tttattctta gaaaatgaaa gcttaaaatc aaatattaca tattgttttt ttgactcatt
    27301 cctagaaatg attaataacg aaaactcata cattcgagca agaggattgt tattaatttc
    27361 cgcaaatgct caatgggata ttgataataa aattgaaata aatatagata gcatactaag
    27421 tcatatcgta gataaaaaac cttttgtatc aagaatgttt attaaatcca tacctaatat
    27481 tacaaagtat aaaaaaaatc tcattcgtcg cataaaaatg gaattaagta atgcagatat
    27541 aagtatttat aataataata tgaaaccatt agtagaaaag gatataaacg atacattatc
    27601 taatcttagt taaatattaa tatagaaatt ggatattatc tagttgcaat tatttataag
    27661 taaaataata aaacaataat ggtgctaatt tttatagata aattaattat gaaaaattta
    27721 tgtaagtaaa atatattaac ataaaggtaa aattttgtac actaaaaggg aatatttaca
    27781 gtttaatggc agttttgaaa taacaagtta aagctgtcat ttttatttga aaatttttag
    27841 aaaaagtaca atcgtgttaa tctgttaact agataaggtt tatataataa tttggatgat
    27901 atgatataaa atatgttgta tattaaatgt tttctttgac aatatatatt caaggatgat
    27961 aatatctata tgaataaaag ctagcgtatc aatttgataa tatgtaatta taacattatg
    28021 ctataattac aataaagtat gtaataatct gtagaaatta caagttagtt atttaatttt
    28081 tcgaataact aaatctaaac ggaatacata atgtactaaa taaatgatga tactaaaatg
    28141 atactatttt tatagaaatt tattgaggta tataattaat gaaaataata tattaaatta
    28201 tataatatat tgagttttac ataaaagcga aggtgggaat aaaaatgaaa gaaattgctg
    28261 atgctataac atcagagtat ttaagctatg gtatcaatga agatattagt atctatgaag
    28321 gtagattttg catatattta gataaaaaat atagatgtaa tgggaaaatt tattataaaa
    28381 tgacacctcc aatatctata agttttaaag cagagatagg ttgtgttgaa gagatagaca
    28441 gtgaagatga caatttagct ttggattatg ataatgctat tcttgaagtt catggatata
    28501 aaattatttc tataacaata aatactttaa gtgaatttag tgtagagggt tatatcaatg
    28561 atgactgcat aaaatctaag aactcctatg ttgaatatgt agattttaat ataataaact
    28621 tagataaaat acctggaaaa ctcattaaat acaatgataa agtatacgca ggtagaattg
    28681 aatttgatat aaatgattat gttataacta tagacaagag gtatgattat agaaaagaat
    28741 taaaattaga attaaaatct aaatctggag caataataac tcatataggt agaattagaa
    28801 gaaaagatgg tagaattttt agaacaaata atacaataaa tcttttagat agaatatcaa
    28861 cagctttgag ttttatgtgt ggaagatatg tagggttttg tttggccaaa gggtatagaa
    28921 gtggtaatga agtttataga atatggaatg aaaatcaaat atctcctttt agatatgtac
    28981 caacatggtc agatacactt tcaaattatc ataatatgga aaaatatata agtcttatgt
    29041 gtaaaaagct agaagatttt tattatggtt ccgctataaa gagtgttgtt gattggtata
    29101 tagaatctct tggaagtgct actatggaaa acaatataat atctgtgcaa attgcacttg
    29161 aaactttgtc atatgcaatt ttagtagaac aaagtaaggt acttacagat gaagcttttg
    29221 actgtaattt ggcatctaga aatataagac tcttacttga tacctgtaag ataccatatg
    29281 gtaaacatga attaaatata tttgataata taataaaaaa taaatttgat gatggagtgg
    29341 atttagttat ttatttaaga aatagcatag ttcatccaag tagaaagact catagagctg
    29401 tattagaagt tgaggatatt tggaatataa tttcaatagg aacgagatat attgagcttg
    29461 ttttactttt tattttaggt tatagaggag aatattcaaa tagattagta gaaaggtgtt
    29521 atggtgaagt ggaagttgta ccttggaact agatttttat atttatttta aaatatatat
    29581 tgacatatat taccttatgc tataaaatca atatcataat aacaattcag aataacatta
    29641 aatgctaaga aaagaaatag taaaagtagt taatcttaaa cagagagttt ccgattggtg
    29701 agaggagcaa tagattttac tttgaacaca tctttgagca ggactctgaa agagtagaaa
    29761 tactttatta ggagctttcc ggaatccttg cacccgttat agtgctagag tataatgatt
    29821 tgttttattg tacttaaaga ggttagtgtc gtgaggcatt aatgaacaga ggtggaacca
    29881 cgagagttaa ctcccgtcct ctagcagaag ctagaggcgg gagtttttta atataatttt
    29941 ttaagcgcgc agagaattat attgcaagag atacactttt taaaaaataa tcaaaatatt
    30001 ttaaaaatta aaaggcgagg gagaatatta tgaaaaatat attaaaaaaa gtaggaatat
    30061 ttacaattat gttaggttta ttaggtggag ttgtaggttg ttcaaagcca gataatgaaa
    30121 aagataagga tgcttcaaag gaatctaaaa aagaagtagt tgtaggattt gataatacat
    30181 ttgtaccaat gggatttcta gatgaaaagg gaaatacagt aggatttgat gtggatttag
    30241 ctaaagaaac atttaagaga cttggaatgg aagttaagtt tcagcctata gattggtcaa
    30301 tgaaggaaac tgaattaaat gattcaaaaa ctgtagatgt attatggaat ggatattcta
    30361 taacagacga aagaaagaaa atagtatcat atacagaacc atatttacaa aataagcaga
    30421 taatagttac tctaagtgat tcaaagataa attcaaaagc tgatttaaaa gataaagaag
    30481 ttggaacaca acaaggttca acagcacttg atgcagtgga aaaggataaa gattttatga
    30541 atagtttaaa aggtggagca ccagttcttt atgatactta tgataaagca cttagagatt
    30601 tagagatagg tagaactagt gcagttgttg gtgatgaagt tttaattaga tactatatgg
    30661 gacaaaaagg tgaagacaaa tacaaagtgt taaaagatga ttttggatta gaagattatg
    30721 ttgtagcaac ttctaaagaa aatccagaac tttgtgagaa aataaatgaa acattaaaag
    30781 aaatgaaaaa agatggaact tttgacaaaa tttatgataa gtggtttaaa tagaagataa
    30841 gttagctgtt aagaaggggg cactaaaggc atgttacaag gtttagagat agttatagca
    30901 atgttttgta taacattgat aatatcaatt ccattgggga ttggagttgc atttttaaga
    30961 ttatcaaaga ataaattagt aagtggtatt acacaatgtt atatattgat aatgagaggt
    31021 acacctttac ttttgcaaat gatagtcata ttttacggat tacctctttt aggaattgta
    31081 tttgacagat ttacagctgg agtagtagct ttcttcttaa attatgcagc atattttgca
    31141 gaaatattta gaggtggaat acagtcaatc gatagaggac aatatgaagc ttcaaaagta
    31201 ctaggatttg ataaatttac tatgtataag agaataatct ttccacaggt ttttaaaaga
    31261 atactagcac ctatttcaaa tgaagtaatc acattagtaa aagatacatc tttagtatat
    31321 atattaggat taaatgatat tttaagaata tctcaaatag caatgaacag ggaagctagt
    31381 ctgttaccat tatttgaggc aggagcgata tatcttatat ttgtagctat acttactaag
    31441 ggatttgaat tacttgaaaa aaaatattct tattatagat aaagttacaa tattatagga
    31501 ggaggttttt atatgttgaa aatcaaaaac ttaaataaat catttaaaaa aaatagagta
    31561 cttaaagata tttcttttga gttagaagaa ggtcagattg gagttttact tggtaagtct
    31621 ggtgcaggaa aaaccacaat attgagatgt ataaatggtc ttgaagaatt tgatagtgga
    31681 gagattataa tagataatga ggtaataaaa aataagagag atatggcaaa aatacgaggg
    31741 aaaataggta tggtttttca aaatttcaac ttatttcctc atatgacagt ccttgaaaat
    31801 ataattgaat ccccagttaa tgtttttaaa gttcctagaa aagaggctga agagagggct
    31861 agagaacttt taagattagt tgatttagaa gacaaattaa attcttatcc atttgaattg
    31921 tcaggaggac agcaacaaag agttgctata gctaggtcat gtgcattgat gccaaaagtt
    31981 ctttgttttg atgaacctac ttctgcactt gatattgata ctattcaaag agtagtcaat
    32041 ataatgaaca gacttaaaga taaaggtatg acaatattaa taattacaca tgatgttgtc
    32101 ttttcaaata atgttgcaga taaaattata agtataaaag atggtatagt agaaaatgtt
    32161 caaataaaag aaaaaattgt ttagagtttt ataaatataa actagggtag aattttataa
    32221 tataaataat gggcaagtaa aatcaaatat actatgccct tttgttgtct caaaatttaa
    32281 tcttatattt tatgtttaag ttacatttaa tttataataa aaataaaagg actatttaaa
    32341 tatataatgt aaataaatgt ttaatttgaa acatgataat tttttatgtt gaaagcttat
    32401 aatcattatg atataaattg gttatagtat acaaattatg ggtataacaa taaaaaatta
    32461 gaaaggaatt tttataaaat gattaaatta tatggatata caaaatgttc tactgttaaa
    32521 aaagcaaaaa attggcttaa ggaaaataat ttagaatttg aagatataga tatggttcaa
    32581 aatcctccta ataaagagga gttaaaatca atttataaga ccagtggata tgatataaag
    32641 aaatttttta atacaagtgg tgtgaagtat agagaattgg gtcttaaaga tattgtaaaa
    32701 actgaatctg atgataaact tttagaaata ttggtaagtg atggtatgct tattaaaaga
    32761 ccattacttt ttgatggtaa aaatgtatta ttaggcttta aagaagacgt atggaaaagt
    32821 actttgctaa aagaagatta gaaggatata ggtgtgttga ttaaaattat taattaatac
    32881 acctataaat ttatgtatta aatctaattc ttataaatat taattagcaa attcaaatca
    32941 aaaaaattca tatcaacaaa catattactt cttgttacaa atgatatcat gtattttatt
    33001 taaaatagta taatattaca acgaattgtt acaaaattac ttattattaa ccatgaacat
    33061 ttgttttgtg ctattatatt tatataaggt aattgtcata aaaaatatct ttttcataca
    33121 gatttatata gaaaaatgaa atgaatattt gctttatata agtatatttt gtaaattgac
    33181 tctatattta tagtttaaat aatagtggta ttaaaaatct gacaacaaaa ataaaacttt
    33241 caaaaaatta aatctaaaaa gaataggaaa taaatatgag tattgaagat ttatatgatt
    33301 ttgaatgtgt tcctttgaac aatgaggttg atattgatgt tttatttgaa aagatgatag
    33361 aagatggaaa agaaaaagaa tatacaccag ttatagtcat tgacgaaaaa gtagggctat
    33421 taagaaaaaa tatcgatata attattaaag agtatggttc tcttgaaaat tatagagagt
    33481 attgtttaac aaaatacaat gaaattgatg taaaccaatt ttttgatttt aggaagcgtg
    33541 agatttcaga attattaaag gagctagttg atttagaaga tgatttttat gattataaac
    33601 attttagacc aattatgaat atagatatat ttcatgaata caataaaatt tacatagcta
    33661 aagttccaac aattaaacca tacgaagtat ttgcatacat acctattggt ggatttaatg
    33721 attgtcctag agatgaagaa cacatagcta ttgcaaaata ttggtatgaa aaacatggaa
    33781 tctttccaat tgcaattgga tgtgatacag ttcaatattc tgtaaaagat ttaattaaag
    33841 atggtaaaaa atttgatgaa ttatgtattg aattagtatt ttattgtgag gatattatta
    33901 tacaagggta tgaaacctta aatgctctta aggatgtatt aaaacgctct acaatattgc
    33961 ttttttggtg ggattgatat aatcaattaa catattgtaa cataggtttg aggaaggaga
    34021 tataaaatat cgttagaact tcgtgtacta gagttacaaa cttgtacttc agttgtaggt
    34081 aaatgatgag ttctttatga cttttaaaca tattactatg ttacactagg tttttataca
    34141 cagtgtagcg cagtaatatg tttaaattta taaagattta aaaaatactt tgatattata
    34201 atttataaaa taaatacttt atatgttata atcattaaga atgtaaaaaa taatatatag
    34261 ttttatagtt catgtttttc tagatatgga ggtaaatttt gtgaaggaaa aagaaaaatt
    34321 agataaatta aaaaaaatgt tacttgaatt aggaagtgtt gtagttgctt attctggtgg
    34381 agtagatagt aattttttgc ttaaggtcgc aaaagataca ttaggtgaaa atgttgtagc
    34441 tgtaactatt catgcaatga tgcattcaag tagagaaatt gaagaggcca aacaatatac
    34501 tcaaaatttt ggtgttaaac atatcatatt aaatatagaa aactttgatt taaaagaatt
    34561 taaagaaaat ggtattgata gatgttatca ttgtaaaaaa tatatattct ctaaaataaa
    34621 agaggtagca aaggaacata atataaagta catagtagat gggacaaata tagatgattt
    34681 aggagattat agacctgggc ttaaggcact gagtgaatta ggagtaatta gtccattaaa
    34741 agatagtggt ttaaaaaaag aagaaattag gtcactttca aaaatattag gattaaagac
    34801 ttttaataaa ccatcatttg cttgtcttgc aagtagaatc ccttatggag ttgagataac
    34861 agatgaaaat ttaagaataa tagaaaagag tgaagaatat ttatccaatt taggtttttc
    34921 tcaatttaga gtgagaatgc atggagatat agctagaata gaagttggac aagaagaatt
    34981 aggtaaattt tttgaaaata acaactttaa taaagttgat actaaattaa aaatatttgg
    35041 ctttaaatat gttacactag atatgtcagg atataaaatg ggaagtatga atttaaatgt
    35101 gtagattatt ttaaaaataa ataagtttta tagttaagat aaagaaacag gaggttttat
    35161 gaaaaattat acattaatat cgccatgttt ttttggaatg gaaaaaatgc tggctagaga
    35221 gattactaat ttaggatatg aaataataaa aacagaagat ggaagaataa catataaaac
    35281 tgatgagttt ggaatagcaa agtcaaacat gtggttgaga tgtgctgaaa gagtacatct
    35341 taaaattgct gaatttgagg caaaaagttt tgatgaatta tttgaaaata caaaaagaat
    35401 aaactggtct agatatatac cttatggagc tcaatttcct atatcaaaag cttcctctat
    35461 aaaatcaaaa ttatacagta caccagatgt acaagccata gtaaaaaagg ctatagtaga
    35521 aagcttaaag aaaagttatt tggaagatgg cttgcttaaa gaagataagg aaaaataccc
    35581 tatttttgta tttatacaca aagataaagt aactatttct atagatacaa caggagatgc
    35641 tttgcataag agaggatata gagaaaaagc aaataaagct ccaataagag agactttagc
    35701 tgctgggctt atttatttaa ctccatggaa agcaggtaga gttttagtag accctatgtg
    35761 tggttctggt actatattga ttgaagctgc tatgattggt ataaatatgg cacctggttt
    35821 aaatagagag tttatatcag aaaaatggag aactcttgat aaaaaaattt ggtgggatgt
    35881 aagaaaagat gcttttaata agatagataa tgaatctaaa tttaagattt atggatatga
    35941 tatagatgaa gaatctatag atatagctag agaaaatgct gaaatagcag gtgtagatga
    36001 atatatagag tttaatgtag gagatgcaac gcaatttaaa agtgaagatg agtttggatt
    36061 tataattact aatcctcctt atggggaaag attggaagat aaagatagtg ttaaacagtt
    36121 gtataaggag cttggttatg catttagaaa attaaaaaat tggtcatatt atttgataac
    36181 atcttatgaa gattttgaat atgagtttgg gcaaaaagca gataaaaaaa gaaagttgta
    36241 taatggtatg ctaaaaacta actttttcca atatccaggt cctaagcctc ctagaaataa
    36301 taaataagtt ttacatgatt catttgtaaa atataaaatt ttattaaaat aagtaaaaca
    36361 ttatgacgcc ttgaaacgtc taattattgt gaggagattt ttgtgaacaa atttaaagat
    36421 ttataggatt aggaggagtt aaatgaaagt gttaaagctt attactgtag tagccatgat
    36481 gatgttattt gttactgggt gtaatataaa aactgaatct ccagaacaat tagcgaagat
    36541 acctaactat gatgatacaa aaaaagtatt gtatgatggt attgaccagt tattaaaacc
    36601 agattcatct atgatattgc cttctaatac aaaagaagta ggaaaaataa ataaggtaga
    36661 tttaaacagc gatggaattg atgaattagt agtatttgaa caaaaagaag atttaagtaa
    36721 taatgtgagt caggtagggt ttgtaacctt gagttacaat ggagaaaaat acgtacttgg
    36781 agaccatttc ttagaaaatg gcgaatcaat agaatatgct aatttttatg atttagactc
    36841 agatggatat aaggaagtta tcttattagt taaatccaaa gataaaacaa atatgcatat
    36901 atataaagta gtagataatg aaataacaaa aatatatgac ttggatgcat catggcttca
    36961 aaataaagaa gattttaatg atatgaaagt aaaaattgga tatatagatg gagatgacaa
    37021 gttagatata ttgatgcttc atttaaataa taagactaat gaaatgtttg caagtgttgc
    37081 aaatttcgat gggagtatga aaatcaaaga ttctgttaag tttgaaaatg taaaaaacct
    37141 aagtgaacta tatataacat taggtaatgt tgcttcgtct gttggaaatt cttcggcagc
    37201 tataaaaggt attgtacttg atatccctat attgaaagat aataattata ttactcagat
    37261 actttatatg aaagatggaa aaattaacaa agcttttagt gattatgata aaactattac
    37321 taaatcttat tatatacctg tagatgatat tgataaagat aagattatag aaatacctat
    37381 agttgcaggt aatacaggta ataatagaaa tacttatagt tctaaagcat ctgcaaatat
    37441 aagttggtat agatggaatg gaaaagaagg tgctgattca agtttaatat ttacaagtca
    37501 gatatattat aattataaat ataattttaa attatttatt ccaaataatt tatttgataa
    37561 aatacttgtt gaacaagaat ttgttggaga aaaggcagta tttaaatttt actattttga
    37621 ctattcagac cgtaagaatt tatttaatat agtagtagag agtaaaaaca aacttgaaga
    37681 tagaaaaaat acaagtactc aaaattctat tgtacttcaa gagagcgatg aatatacttt
    37741 cttactagtt gtaaacaatg caaatgaaat ggataagcta gatatgacta tagacgcatt
    37801 aaaagaatat ttctcattaa tatatggtta atattatact caattggagg ttttatttta
    37861 tgaaggaaaa aatacttata ctagaagatg aaattggtat tagaagtttt gttagtataa
    37921 acttaaaaag agaaggctat gagatagttg aggcaggtac tggaagagaa gctatagaaa
    37981 aaatgacaac agaaaatgat attacaatag ctcttttaga tgtgatgctt ccagatataa
    38041 gtgggataga ggtatgtaaa tttataaggg agaattttga ccaagtaggt ataataatgc
    38101 ttactgctaa agctcaagag gatgataaaa tagaaggatt tatttcaggt gcagatgatt
    38161 atattataaa accatttagc ataaaggagc ttttagttag agtttctgct cttattagaa
    38221 gagtagcaaa agatgattca agtgttaaat caagtgaaat agtatctcca ccatttatac
    38281 ttgatataga caaaagaaaa ttatttaaaa atggaaagga aattgagctt acaccaactg
    38341 aattttcaat agtgaaatat ctaatatcaa atgctaagca atcgttaagt agagaccaaa
    38401 tattagatga agtgtgggga actaattatt tatatgattt taaaatagta gatgtaaata
    38461 taagaaggat aagaaataaa atagaagatg acccatcaaa accaaaatat atacaaacta
    38521 tttggggtta tggatactgt tttagaaagg aagaataata gtgttacatt ttgaaggtct
    38581 gagaaaaaaa gtaataaaaa actattttat aataattatt ataatggtta ctctgtttga
    38641 aggattgttc atgttttaca tacaaaacta ctattatgat tctgtcaaac aactacttga
    38701 atctgaaata aaatatgctg atgaatataa tgctattaca atggaaacta caagttttga
    38761 gaaaaaagta aaaaatatat ttgataaaca acctttaact aaaaattcag aatttggaat
    38821 ttcaataata gataaggata aaaatattat attagaccaa tatggcttta aaagcaaaga
    38881 aaaagcaaac tatgaagatg ttaacaatgc attaaaagac ataaaaacta aaaatttaac
    38941 accatatact tatagaatac cagatacagg ggagcatgtt atgagtatct ccttaccact
    39001 taaagtaaat aatataatag aaggtgttgt tagatataca gtatcattag atgctattga
    39061 taatgcgata ttaaagcaag ctacatggct tatattagca ggaatattta tacttattat
    39121 agctatacta ataagtctta aatttgctga gactcttata aaaccattac gagagttaaa
    39181 gaaatttgca aatgaattgg ctgtaggaaa ttataatata aaattagaaa agatgaagat
    39241 tgtagatgat gaaattggtg atttagcaca gacatttgaa catatggcac atgagattga
    39301 caaaagtgaa aaattaaaag aagaatttat atcatctgta tctcatgaac taaggactcc
    39361 tcttacatcc ataaagggat ggagtgaaac cttaggctat gaaagtataa caagagaaga
    39421 gttagactta ggtttaggta ttatacaaga tgaaacagaa agactcataa agctagttga
    39481 agaattatta gacttttcaa gactttcttc agatagaata aagcttcatg ttgatatagt
    39541 tgatgttgaa ggtttaatcg taggtgttgt aaatcaactt aaagttaaag cagccgaaaa
    39601 agatatatca cttttgtttg aatttgaaaa tgaatttata gagaacatcc aaggagataa
    39661 aaatagatta agacaggttc tcataaattt aatacaaaat tcatttaaat ttactagtca
    39721 aggtggttac ataaaagttg tagcttttca agatgaagag ataacaacca tatcagtaga
    39781 ggataatggt tcaggtatag aaaagcaaaa tttaaataaa gttttagata aatttttcca
    39841 agaagattat aataaggctg gtagtggatt aggactagca attagtaatg aaatagtaaa
    39901 acttcatggt ggaagaatga aaatagaaag tgaaaagaat gttggaacaa aaataacttt
    39961 taatataaaa aataagtttg ctaaacaagc ataaattctt agaaagagga ttaagatgag
    40021 aaacataaaa atgatagtag catatgatgg ttcaagatat aaaggatatc aaaaactagg
    40081 tgacaataat atgactattc aagaaaaact tgaaaatgtc ttaagtaaaa tgactaatga
    40141 aacagtggag ataatcggct ctggaagaac tgatatggga gcccatgcaa gaggacaagt
    40201 tgtaaatttt agaactaatt gtatggattc tttggataaa attcaaaaat atctatatga
    40261 atatttacca gaagatatag ttgtaaaagc tgttgaagaa gttgatgaga ggtttcattc
    40321 aagatacaac gtaaaatcaa agacttatat gtatagaatt gacaataata agtatcacaa
    40381 tccttttata agaaaatatg ccactcatgt aagtaaaaaa ttagatttgg atagaatgag
    40441 aaaagcaagt gagtatttag taggagagca tgattttact agttttgctt cttctaaatc
    40501 taagaaaaaa tcaaatgtaa gagaaattta ttctataaat ataaaagaag atgataatat
    40561 tatagaaata tatgtagaag gaaatggatt tttgtataac atggtaagaa taatagtagg
    40621 tgctctaata gatgttggtc taaaaagaag agctccacaa gatattaagt atatgcttga
    40681 atcaagagat agatgccaat catcagacac tgcaccagct aaaggactat gtctttggaa
    40741 agtgagatat tagtcaatta tataaagctt tctttaaaat aaaaataaaa taaattatat
    40801 agttgacata aatggaaaaa taaactatta tatattttat aagagagata taaaacttta
    40861 tatttaaatc ctgtgagaaa gagagtaact tctatgtgtt ttatagagag ctgaggatgg
    40921 tggaagctta gcaaataagt attagtgaaa agaactttgg aggatactaa ttgaatttag
    40981 tatgttagta ggtaatctcg ccttaagaga aagagtggat aagtttatct tatcaattag
    41041 agtggtaacg cggatatatt tcgtctcttg gtttttccaa gaggcgtttt ttaatatatt
    41101 taattactag tgtttattta gtatgttgaa catttactaa ttgattagct aagtttatca
    41161 ataagagtgg taccgcggat atttcgcctc ttagtatttt aaaatactaa ggggcttttt
    41221 tagtattaaa atgattttat gtgaatctaa attctcaaag tcattcaata ttaagaattt
    41281 ctataaaata aaaattataa tttaagattg ggaggaatta aaaatgaagg aaaaagtagt
    41341 attagcatat tcaggaggac ttgacacatc aatcataata ccttggttaa aggaaaatta
    41401 tgaagatata gatgttatag ctgtttgtgg aaatgtaggt caggaagata aaatggaaga
    41461 tgtgtatgaa aaagctttac aaagtggagc atcaaaggca tatgtggatg atataagtga
    41521 agaatttgta actgaaacta tatttaaagc tgtaaaagca gaagctaaat atgaaggaaa
    41581 gtatttatta ggaacttctt tagcaagacc tataatagcc aaaaaattag ttgaagttgc
    41641 tcataaagaa ggtgctaaat atatatgcca tggatgtaca ggaaaaggta atgaccaagt
    41701 tagatttgaa gctacaattg cagctcttga cccgactata aaagttattg caccttggag
    41761 aatttgggat ataaaatcaa gagaagatgc tatagactat gctgaaaaac ataatataaa
    41821 ggtaacagca actaaagcta aaatatattc agtagacgct aacctttggc atgtgtcaac
    41881 agagggtgga gatatagagc atctagaaaa tgaacataaa aaagatgttt acaaacaatg
    41941 tgtagaccca gaagatgcat gtgatgtggc tgaatatgta gaaatttatt ttgaaaaagg
    42001 tgtacctaaa aaggtaaatg gagaagaatt atctccagtt gcactgattc ataaattaaa
    42061 tgagttaggt tgtaaacatg gaattggtgt tatagatata gttgagaata gacttgttgg
    42121 tatgaaatca agaggtatat atgagactcc aggaggaaca atcctttatg aaacacataa
    42181 tattttagaa agtgctactt tagacaaaga tacattacat ttcaaacaaa tggtgtctta
    42241 taaatatgga gaacttattt acaatggatt atggtattgt aaattaagag aatctataga
    42301 tgcatttatg gagcaaactc aagataatgt tacaggaaca gtaaaagtta aactttacaa
    42361 aggtaacata aaacctgctg gaatatttac tgaaaatgct ctttatgatg aaggaatatc
    42421 ttcttttgga aatagtgaac tttatgacca caaagatgca gaaggattta ttaatttatt
    42481 cactttacca ttaaaaatca gagctatgaa agctggaaaa taataaaata gattattcaa
    42541 gagtatgtaa aaacgatttc taggttttta tatgctcttt tttatttgga attattaaat
    42601 tatgcagtaa acaatataac aaaatatatt atagtatcaa atcggttatt aatatgaaaa
    42661 tataatacct aaaatataaa ttttataaat ataatagtta tctattgact ctctcattgt
    42721 aagagggttt atactgaatc tagcaaaaac ttatagtgag gagatagatt atatgagaaa
    42781 aataattgaa atcaaacatc attcacatga ttatgaatgt atgtggaatg gtatagaaga
    42841 tttatatata aataaaacag gtgaatgtct tccaaacaat tttttctttt tgctatcagg
    42901 ttttggttcg ttttgttata tgaaaacaaa taaatcggag ttaaaaagaa tggtagcttt
    42961 gggagatgga aggacaaaaa agatgtataa attcttagca ccaattgtcg gttttgaata
    43021 caaacatcat gagtttaaaa aatatgagca agcattaaag aaagcaaaat ctgaaattga
    43081 tagtggacat ccagttgttt taggagcttt agatatgtat tatttaccat attataaaaa
    43141 gttatatcat atagagcatc ttccttttca ctatgtatta atggtaggat atgatgatga
    43201 aaaagtatat ttgtatgatt gtgggagaac agaattatta aatctttctt atgataaatt
    43261 acgtgaaagt atgaattgca gttatcctgg attaagcaaa gaaaatacta tttgcacaat
    43321 aagaatgaac acttcaaaaa ataaatataa aattgctaaa gaagttattg ctataaagcg
    43381 tgatatgttt ttaaatccac ctaaaggatt tttgggatat aaaggttttg aaaagtttat
    43441 taaagagttg tcacagtgga aaactgaatt ggagaaagat gattatgata agattttgac
    43501 caatatgatt atgttttttg gaacagtacc aacaattcca aatgcaatca aaggaattaa
    43561 agaaccagac actattcaat ttaaaggtgg atttgacaaa atgagtaaaa tgcttaaaag
    43621 tattggagag gaatataaaa atgactcttt tatacaagta gctgagattt ttgataaaac
    43681 ttctcttata atcgagaaaa tatccaatat tatagtagat tatttgactc agaaatatga
    43741 tgatacagac caacttccat tactattctc tgaggtttta aaggatatga aaacaggata
    43801 tttaatattg aatgtataaa aatagattat tgactctaac attacgtaat agtgtaatat
    43861 gaaaatatag cttgaataga ttcgtaaagg ttgatagcta taaaatcaaa tttgaggtgt
    43921 agatatgaga acagtaaaac aagtttccga tttaactgga ataagtgtaa gagcattaca
    43981 ttattatgat gaaataggtc ttttaaaacc aaataaaatt acagatgcag gatataggct
    44041 ttatgatgat gattctatta aaactcttca acaaatttta tttttcaagg agattgatat
    44101 tcctttaaga gaagttaagg agataatgtc aagcccgtat tttgataagt tagaggcttt
    44161 aaaaaatcaa agaaaattac ttattttaaa acgaaaaaga ttggacgaat tgatagaact
    44221 tataaatcaa accctaaggg gagaaggaaa tattaatttt aaagagtttg atatgagcga
    44281 gtattttgat gttttagaag aatttaagag agagcataag agtaagataa ttaaaattta
    44341 tggtagtgta gaaaaataca atgaatatat agaaagagtt aaattcaatg aagataaaat
    44401 tgctaaaatg gctataaaac aatatggaac tattgagaag tttgcccaag ctataaaaac
    44461 aaattttagc agtgatatat tgaatttagg agaaaaattc gatagataca aaaatgattg
    44521 tttaaaagag caacatccaa aattaaaaga attatataga aagcttgctg aagatttaag
    44581 caaaaatccc tcttcaacag aacttcaaga aatagcaaag gagataacag atatatctaa
    44641 aaaagattat gaaattttct ctatggatac tggtgatgac aactggtatt atatggttca
    44701 aaattatctg gtaaatccta tgtggataga agaagtagat aaaaagtatg gaagtggagc
    44761 aggcaagttt attggacaag tactaaaaac ttatctaaga gatagaaaac caaagataaa
    44821 tacattgtat gaaaaacttg tagaagattt gagtagagat tgttcttcaa aggaaattca
    44881 aagcattgtt gaagaaatag acaatgaaat gaaaagaagt aatgactttt ataaaataga
    44941 caatggagaa agatactttg attatatgtc agagctttat ttacaagatt ctaactacat
    45001 aaaagtaact gacaagaatt atggtaatgg tgcatctaag tttattggag aagcttttaa
    45061 gatttatttt gataataata attgttgaaa atttggaaat aaaaaatgtg taagcttcat
    45121 aaaagcataa aagtaaggat atagattagc tccatctata tccttattta aagtcattaa
    45181 aatatataat ttacatcaaa cttgacactt tcaatgatat ttcccagata tgtttttata
    45241 ctttcaattt cttctaaaga ttttaattta ttttcagtat aaattgcttt gtccagaata
    45301 ttaaatctta atcctatttc atcaaagtac tcatgattta aaactttgta ccaatggttt
    45361 ttttctttat tccaacttgt agatattgaa tcagcttctt tttgagcttt ttcccaattt
    45421 tcattttcta tagatttttc taaaacagat atattgtttt tatatccttc tgtaaaatca
    45481 tatagtttat tgttaacgta aaatccaaat aatacaaata agatagtcca tagtataaca
    45541 aatgttgtag atttcaatat taatcaccct ttttattttg aataaatatt ttgtcatttt
    45601 catctaaaac acaaataaga acatctttaa aagtttctat gtgattagat tttaaaatac
    45661 ccattaacca gttagtatct ttttgagcta tgtctagatt tttatttatt attctaccat
    45721 ccagtataag tggaataggt aaatgattaa aagctcttgg aggagtacta ttgtagcttg
    45781 atgctggtac aacacttaga ttaccatcag tctccaaaat agcatactgt acatctttta
    45841 ggttaaagta tccctgaatc ctaagttgct ccaataattc atctatacta actctttctt
    45901 ttttaagctc tttatataca atttttccct tatctattaa cacagaaggt ttacctgata
    45961 aaaatgaact taattttctg ctttttaatg ataagaatga aattagagtc tgcataatta
    46021 caagtccaga tattgctgca acaccattta taattggtat attattattt tccattggga
    46081 cagatgcaac ttctgcaatt aatagtgtta taactaaatc aaaacagttc atttcagcta
    46141 tttcaccttt tcccatgact ctaagtgcaa ttagcactgt tatgtataat ataatacttc
    46201 ttattaatac tactgtcata tctatcaatt actcctttaa aaaatattta cacttagtta
    46261 gtatgtccta tataaaaatt ttaattcaaa gtataaaaaa ccttaaataa ttggattcaa
    46321 ctacttaagg tttttttgat aattttaata ttaaattttt tatagatttt ctgttacttt
    46381 tatttatttt aataacagat tcaacaaaac tctttttatc tcctaatttt aagataaaat
    46441 caggatattc ttcaaattca ttgattttta ttaatttgaa agaagaagat agatttttaa
    46501 agttaataat tttagagtta ttcactaaca cacttctttt tttaaaataa atttcttttt
    46561 tacttatatt tagtatattt aatatttgtt taagatatac tattatatct tctggagttc
    46621 tatcaaattt gagttcaaaa ttttcatctt caaaataggg gatataatat aagggtgttt
    46681 tgaaagcagg taatttatta tataattctt caagaatatc gatattttta gggtagttaa
    46741 agaaaaagca tttacataca ttcattaaat ccatagcatc cgaaagtgag ttatgtttaa
    46801 tatctccttc tacagaaaaa atttttttca tattcagtaa agatatttgc ttagataaga
    46861 ttctattatt atatgtaata tgttgagata taaaaggttg aatatcaatc atcatattaa
    46921 ataactctaa gcacttacct gtatatttat atactctaaa tgaagttaaa agaccaatta
    46981 tatcaaaatc accccagtta tatattgtaa catcatcaaa tttacaaaac catttataaa
    47041 aatcatccat aacatataaa agattaggag cattattgat atctagttgg ttcaatttgg
    47101 ttaagttttt acatttattt gaaagtattt tattgtatct tggcttaact aaagagtaat
    47161 aattatctat tgtattaaat tcattatcaa ctaaaactcc accaatagaa attaactcag
    47221 tgccattata ttcttttggt ttatttttat tatcatctag tatattaaat tcaaagtcta
    47281 taaataactt gtatttcata aatctaaagc acatcctcag gtaaattatt tattgagcct
    47341 aatcatcata agaatcaata gatataatga ttctaaacat caaaggttca ttgcaacttt
    47401 tatttatttc ataatttaat tcaaataaat cttttaagat ataatttata agtattcttt
    47461 cccaacccat ttttaaatta accttagagt ctagtaatat attttctatt tttttaaata
    47521 tttctatatt tgctggtatt atactgagct caatattact tttaaacggg ttagactgta
    47581 aatctgttat aattatactt tttaattcat ctgtaagttc agaaattaaa atatcaccta
    47641 tgtatttttt tattatttcc tctctaattt cttttaaatt tagcaatatt agtacctgct
    47701 acttaaacag tagcttttcc tttcttttta ataatattat ttatttttga atcttatttg
    47761 gatatatttt aagattaaaa gttttcacct atatcatttt ttatctaatt taaacttata
    47821 ttaacatatt ccaggcttat atctccaccc tgcttatgtt aaaggtggag tatgttgcct
    47881 attttgatga aaaatgatag gttactattt acctattcct ttttctgata atttttctaa
    47941 catatctttg gtcattttat ctaaatcata actaaactta aagttccatt cttttactgc
    48001 actactactg tctagagaat taggccaaga atcagctata ctttgtctta cagggtctac
    48061 atcatactct attacaaaat caggaatata tttttttata gaatcagcta tttcttcagg
    48121 agaaaagctc atagcagtaa tattaaaagc atttctatgg ataagtttat ccgctggagc
    48181 ttcgattaaa tccactattg attgaagtgc atcaggcata tacatcatat ccatttttgt
    48241 accttctgct atgtaagatt tatatctctt gttttttaat gcttcataat atatatcaac
    48301 tgcataatct gtagttcctc caccaggagg cgtaacataa gaaataagac ctggaaatct
    48361 aacacctcta gtgtctactc caaattttga atgataataa tcacatagta attctccaga
    48421 aactttagtt acaccataca tagtattagg tctttgtaat gtgtcttgag gcgtcatatt
    48481 ttttggtgaa ttttcaccaa aggcagcaat tgaactaggt gtaaaaaatt tacaatccaa
    48541 ttctctagct acttcaagac catttattaa tccattcata tttaagttcc aagcttctag
    48601 aggtttactt tcagcaactg cagaaagtaa agaagctagg tgaattatag tatctacatc
    48661 atattttttt gcgatttcaa aaaaacgatt ctcatctgta acatctaata tttcaaatat
    48721 accagattca catactggat taccttcttt tgctctcctt gaactagcaa ttacattttg
    48781 ttctccatac tcatttctaa gctttattgt taattctgaa cctatttgtc ctaatgcacc
    48841 tgttataagt atttttttca attttataac ctcctaaggg tttaatttat gtagtactac
    48901 ttatttttat tttagcaaat cttttgttta aatacaaaga attaaagata ataatatatg
    48961 gtctaattga attaagtgca gtaaaggtct aaaaattaaa agttaatata taatggtcta
    49021 ttgtataaca ataaaagact agattaaa
//
LOCUS       DAMKOJ010000023        48075 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000023 DAMKOJ010000000
VERSION     DAMKOJ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48075
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.024"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            89..826
                     /gene="cas6"
                     /locus_tag="PC592_001422"
     CDS             89..826
                     /gene="cas6"
                     /locus_tag="PC592_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF4055411.1"
                     /translation="MSRISVFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            831..2297
                     /locus_tag="PC592_001423"
     CDS             831..2297
                     /locus_tag="PC592_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055412.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKSDYKLKFT
                     CELNRNYLSLESAENIDPKYISDYILENQLFKVFKNGKKEALEKIFNNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMEINVKNIVDTVIKSN
                     IEIDKIDLEQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKRSGQ
                     VESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKSFYK
                     KLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREPGNT
                     KNLGKKMIDNGNLSNLKELLLDNISFLKPSNGTSREMDFVSSSYNIGLYIKLCWIVDG
                     GDEYKMKNYTESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQTIMH
                     VLVSNGILIGDGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            2316..3329
                     /locus_tag="PC592_001424"
     CDS             2316..3329
                     /locus_tag="PC592_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HDF4055413.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIIFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYIGSTQLITNRGFLSSEFGRKYYDEKEENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            3345..4142
                     /gene="cas5"
                     /locus_tag="PC592_001425"
     CDS             3345..4142
                     /gene="cas5"
                     /locus_tag="PC592_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF4055414.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKDVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            4169..6577
                     /locus_tag="PC592_001426"
     CDS             4169..6577
                     /locus_tag="PC592_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF4055415.1"
                     /translation="MENIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINDILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIED
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILDEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLNTRNSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIAFIESNKEENICEGKDVKVS
                     FIKEKEIKSIVEGALENKQKILIIKNTIDSVNRTYEFLKENLSDKYSGVDIDVLHSRF
                     KFKDKKEKYSKILNGKGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKSILNNVIKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEDNFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYRLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            7016..7963
                     /gene="prmA"
                     /locus_tag="PC592_001427"
     CDS             7016..7963
                     /gene="prmA"
                     /locus_tag="PC592_001427"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDF4055416.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKN"
     gene            7982..8740
                     /locus_tag="PC592_001428"
     CDS             7982..8740
                     /locus_tag="PC592_001428"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDF4055417.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRYKPGEKLEICD
                     KNNNEYICEIVNIDKSIVNLNILEKVDINRESELKIRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVAKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLTFKEAL
                     EDMKKNNINICPYENERTVPMKHALQNCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            8742..10040
                     /gene="mtaB"
                     /locus_tag="PC592_001429"
     CDS             8742..10040
                     /gene="mtaB"
                     /locus_tag="PC592_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDF4055418.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INKIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRKLDVLFEQNLEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10083..10433
                     /locus_tag="PC592_001430"
     CDS             10083..10433
                     /locus_tag="PC592_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HDF4055419.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDITDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10596..10775
                     /locus_tag="PC592_001431"
     CDS             10596..10775
                     /locus_tag="PC592_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDF4055420.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            10805..11248
                     /locus_tag="PC592_001432"
     CDS             10805..11248
                     /locus_tag="PC592_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDF4055421.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11359..11856
                     /locus_tag="PC592_001433"
     CDS             11359..11856
                     /locus_tag="PC592_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF4055422.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLVYLMWLVYAGFLNYFI
                     WFINK"
     gene            12049..12606
                     /gene="raiA"
                     /locus_tag="PC592_001434"
     CDS             12049..12606
                     /gene="raiA"
                     /locus_tag="PC592_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF4055423.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENVDFIDNSSEFDDYDDEEYENIVIERRKKFNVKPMSSEEAILQMELVGHNFYMF
                     RNQDNFEINIVYKRKAGGYGLIEQD"
     gene            12820..13056
                     /locus_tag="PC592_001435"
     CDS             12820..13056
                     /locus_tag="PC592_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HDF4055424.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13069..14394
                     /gene="yqfD"
                     /locus_tag="PC592_001436"
     CDS             13069..14394
                     /gene="yqfD"
                     /locus_tag="PC592_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HDF4055425.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRSELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEIPSNPEKRPLNDIRNEFDEDNKDNKEQNNSDENNSNQNSNSNNN"
     gene            14432..15448
                     /locus_tag="PC592_001437"
     CDS             14432..15448
                     /locus_tag="PC592_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDF4055426.1"
                     /translation="MIIQKKFTIADGNFERELFGNFDENVKLIEKTLNIDVILREGNI
                     ILIGEEKNVDSALKLMNELHQTVSNGKHLDKQSISYSLSLLLEGSEQKIKELEGTIVI
                     TQRGKAVQPKTLGQKEYIKLIENNDITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRII
                     LTRPAVEAGESLGFLPGDLKDKVDPYLRPLYDALFEMLGADKFNKYLERGTIEVAPLA
                     FMRGRTLDNSFIILDEAQNTTSEQMKMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLI
                     QATEILKGVPGIGSIMLTDRDVVRHELVQRIIRAYEKHDKREEFKKEERKKAKMQEKT
                     FKRK"
     gene            15505..15966
                     /gene="ybeY"
                     /locus_tag="PC592_001438"
     CDS             15505..15966
                     /gene="ybeY"
                     /locus_tag="PC592_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDF4055427.1"
                     /translation="MDLILDDRQDKLEVSEELLEKIKDIILECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            15972..16691
                     /locus_tag="PC592_001439"
     CDS             15972..16691
                     /locus_tag="PC592_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDF4055428.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            16810..17211
                     /locus_tag="PC592_001440"
     CDS             16810..17211
                     /locus_tag="PC592_001440"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF4055429.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSSFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHDIKDLLPNYFSGNDLK"
     gene            17276..18169
                     /gene="era"
                     /locus_tag="PC592_001441"
     CDS             17276..18169
                     /gene="era"
                     /locus_tag="PC592_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDF4055430.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18181..19560
                     /gene="mgtE"
                     /locus_tag="PC592_001442"
     CDS             18181..19560
                     /gene="mgtE"
                     /locus_tag="PC592_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDF4055431.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEQREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIVARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLKEQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            19633..19788
                     /locus_tag="PC592_001443"
     CDS             19633..19788
                     /locus_tag="PC592_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HDF4055432.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            19754..20527
                     /gene="recO"
                     /locus_tag="PC592_001444"
     CDS             19754..20527
                     /gene="recO"
                     /locus_tag="PC592_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDF4055433.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTVSLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20520..21119
                     /locus_tag="PC592_001445"
     CDS             20520..21119
                     /locus_tag="PC592_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HDF4055434.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21279..22157
                     /gene="glyQ"
                     /locus_tag="PC592_001446"
     CDS             21279..22157
                     /gene="glyQ"
                     /locus_tag="PC592_001446"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDF4055435.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22157..24223
                     /locus_tag="PC592_001447"
     CDS             22157..24223
                     /locus_tag="PC592_001447"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDF4055436.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKDEYIFATIKQDGKETSEVLKDILPDTIKSVVFPKAMRWGGKNLKFARPI
                     RWIVTLLNDKVLEFDLEGIVSSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIVGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNREEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVRVKQ
                     LLKDKKYGVALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(24390..25937)
                     /locus_tag="PC592_001448"
     CDS             complement(24390..25937)
                     /locus_tag="PC592_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HDF4055437.1"
                     /translation="MDNFKKILLNEIPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSHHQLNKIYEMAIKHNLDKIHLTTRQAIQLHDLSIDSIVDI
                     MKEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEAFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEQYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLKKFKEYYKLEKENGG
                     LELNIEEIDYSKSGVKICIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLNTLLKELDN
                     IENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGVST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASTGNFYEWVNSNDDILNK
                     ITDKYKI"
     gene            26217..26984
                     /locus_tag="PC592_001449"
     CDS             26217..26984
                     /locus_tag="PC592_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF4055438.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            27269..27466
                     /locus_tag="PC592_001450"
     CDS             27269..27466
                     /locus_tag="PC592_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4055439.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            27495..28571
                     /gene="vorB"
                     /locus_tag="PC592_001451"
     CDS             27495..28571
                     /gene="vorB"
                     /locus_tag="PC592_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF4055440.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            28574..29293
                     /locus_tag="PC592_001452"
     CDS             28574..29293
                     /locus_tag="PC592_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF4055441.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTVEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            29306..29845
                     /locus_tag="PC592_001453"
     CDS             29306..29845
                     /locus_tag="PC592_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF4055442.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIRVPVTEIAQNLGNEKAANICMLGAMVKNLDLFTKEEFENGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            30002..31060
                     /gene="buk"
                     /locus_tag="PC592_001454"
     CDS             30002..31060
                     /gene="buk"
                     /locus_tag="PC592_001454"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF4055443.1"
                     /translation="MKILVINPGGTSTKISVFKDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFEDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKQGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVIEKVSYIAPVEVVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            31078..31971
                     /locus_tag="PC592_001455"
     CDS             31078..31971
                     /locus_tag="PC592_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF4055444.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIENISKEIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMVNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPNCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            32001..33209
                     /locus_tag="PC592_001456"
     CDS             32001..33209
                     /locus_tag="PC592_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF4055445.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEVTQKVLKERGKFALAYGPTKGEDELLELLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVSKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIREEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            33233..34492
                     /locus_tag="PC592_001457"
     CDS             33233..34492
                     /locus_tag="PC592_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4055446.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEKEEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            35137..36600
                     /locus_tag="PC592_001458"
     CDS             35137..36600
                     /locus_tag="PC592_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF4055447.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAVSWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTTLPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKYEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKENKHELN"
     gene            36656..37792
                     /locus_tag="PC592_001459"
     CDS             36656..37792
                     /locus_tag="PC592_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF4055448.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKIAEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLIDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVEIFTKVMEEFGIYEDEQVLLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINPYAKDRVIDGIKILALTGFNLFENSELLKKMKEE"
     gene            37817..39235
                     /locus_tag="PC592_001460"
     CDS             37817..39235
                     /locus_tag="PC592_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF4055449.1"
                     /translation="MTNKTEGKKKKLTFPDAYVLMIGLIVFAAIMTYIVPSGTYSRIE
                     DLNTGNMLVQAGSFKYGEQHPVSIMDVFRAIPSGLGKNSVTIFFVLIIGGAFGIVNFT
                     GSLDVLIGRVISKSQGSKKGEIIITSLVLTFGLAGGVVGMYEECIAFLPILMTLCIAL
                     GYDALVAAGILLLGLASGYGSATINPFTVGLAQGISGLPLFSGMWFRWIFWICTMILL
                     SGYIIFYCKKIKKDPSKSLVSDIDYSHWQLDESSIKEKLSSGNIRVLVTFFGGILVLM
                     IIIVKFSLGMSDLSAYFFALGILCGVVYGMSPNKIASAFVKGMQEMVYPAILIGFASS
                     IVVILEQGVILDSIVHGLSLVLNYVPRIFSGGVMMIMQSIINLFIPSGTGQAMVTMPL
                     MAPLADVIGVPRQVAVLAYQMGDGFANGIVPTLGVLMAGISIAHIPYTRWFKFASKII
                     LMELVLGFIFLMISVQINLGPF"
     gene            39447..40565
                     /locus_tag="PC592_001461"
     CDS             39447..40565
                     /locus_tag="PC592_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDF4055450.1"
                     /translation="METLKIRNIELSGTNYEIGYELGKLIANTPKILEGQINKSNVVT
                     KEEEKEMLELFDKYCPGLNEELKGFADAVQVNCNQILYYTMTYLKPGCSQVALAPELT
                     TNGHVLFARNFDFSHNMEDFVLCKTKVKGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSVGLRKPAVVGLQFWAVIRYLLENCKDVDEALEYIEDMPIAYNINLLLADK
                     SGNIALVETLDGKKGVNRINRLEKQREHFLHSTNHIHIDELHKLEPQSIKNSIHRYKL
                     IKEYINNSKKVGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNTGKFNILWGG
                     LESNNWESYYLKDDVKATTHLININIEKAPSDFFDFVE"
     gene            40716..41585
                     /locus_tag="PC592_001462"
     CDS             40716..41585
                     /locus_tag="PC592_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4055451.1"
                     /translation="MDYLEYFEKAVIYIENNLQENITVNDVAKESGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVNSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGNKKKLELDFMRHLIGNITIKPVIKEIDEIKIIGIKDKVILENNSLPE
                     LWDKFRKVHQIVPNTLPSERVFGICEATSEIHLISESMEFNEIIGVEVSSYESIPNSF
                     VSKTITEGKYAVFTHTGSLENLDKTYEYIWGTWFLNSKEEFDTRDDFEVYDERFLGPN
                     NINSQIDIYIPIK"
     gene            41960..42505
                     /locus_tag="PC592_001463"
     CDS             41960..42505
                     /locus_tag="PC592_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF4055452.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNKVADKA"
     gene            42518..43531
                     /locus_tag="PC592_001464"
     CDS             42518..43531
                     /locus_tag="PC592_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF4055453.1"
                     /translation="MDENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEVVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVSPNCISVVNGEDMQKKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     AKVISPLAGNIGGLLIISIICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPISVIIAYGVAVF
                     ALR"
     gene            43753..45726
                     /locus_tag="PC592_001465"
     CDS             43753..45726
                     /locus_tag="PC592_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF4055454.1"
                     /translation="MSVTEKIPSIDHKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAIIKYIKGQGYKLEIKDEQILNKIIDINRKNVFSLNSKEDRVEF
                     ILNYLTELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFNNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKETKKVKDYDVKFDLLKSYDEYFIAREIKHIISEMFECILNDEE
                     IIYLTIPLVSGNAPASECALNSSRINKNIDELMESIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILDSLEKMMDNLMDLGCIDDKFRKNIFNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIKYANRNIKIILMTMFPCENKMDSDLLVKIYE
                     EILKIGQDVKLTNKISKCRSFLEFKKVLLKNLM"
     gene            45796..46155
                     /locus_tag="PC592_001466"
     CDS             45796..46155
                     /locus_tag="PC592_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055455.1"
                     /translation="MKVLVILFAAYILNTILIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSNGFIKFGEILKGRTVMAKFKEIEDIEGLDIYSAEQKFKNEES
                     IVQAIKFIKEKINVSFN"
     gene            46190..46546
                     /locus_tag="PC592_001467"
     CDS             46190..46546
                     /locus_tag="PC592_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF4055456.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     ISTLRSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKNEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            46583..47875
                     /locus_tag="PC592_001468"
     CDS             46583..47875
                     /locus_tag="PC592_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF4055457.1"
                     /translation="MLDLNRKLAKLEEEGKKIRVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNENDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAEIKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLEHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEYMDGYGAYTCYGTIEKYDVAKAMKAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
BASE COUNT        19101 a         4883 c         8942 g        15149 t
ORIGIN      
        1 tataaaaaat taatagatat atatctatta attttttata ttacaaatag agaataatgg
       61 attatactag aaagtaggag gtgaaaatat gagtagaatt tcagttttta tggagtcatg
      121 taatggcaaa tttccaaatg aaaattcaat gttgtcagtt tcctttataa aaaatatttt
      181 aaacgcagaa aacaaagatt ttgctaaaaa tatatttaac tatggggaag aaagaaaaaa
      241 caataagcaa ataaaggata taaatacagc catctacata ccaaatctta taagaagcaa
      301 aaatgagttg cttgttgatg gagatataat attcaatata agtttttata attattctat
      361 gttcagtaaa ttatacaatg gaattttaaa agtaaaggag ctagaatata aaggttatag
      421 atttaaaata aaaaatataa aaatacataa agaacatgag ataaaagaaa atggtgttat
      481 atttaaaact atgtctccta taatagtaaa gaataaagaa ggtaaatatt tagatgtaga
      541 agattcaaat tatatagaat gtttaaacta tatagctaat ctaactctgg agagtataag
      601 aggtagtggg cttagaaagc cattggaatt tatacctctt aacttcaaaa aaagagtgtt
      661 aaaagaaaag attcgtggat ttaaagagag agaattttac tatataaatg cttatgcagg
      721 aacatttttt ttaaaaggag atatggaaga tttaaatgca ctgtataaaa tggggattgg
      781 atatagaagg acggaaaatg caggaatggt tgatatatta aagtagcgag gtgagagaaa
      841 taaaagctaa attttataga tcaggtgata ttgtaagaga tattggcatt gtttactttt
      901 atgaattact aatggattta aaaaacgaac tagaaaaaag tgattataaa ttaaaattta
      961 cttgtgagtt aaatagaaat tatttatctt tagaatctgc agaaaatata gaccctaagt
     1021 atatatctga ttatatatta gaaaatcaac tttttaaggt atttaaaaat gggaaaaagg
     1081 aagccttaga aaaaatattt aataatatag ataatttaac gtatgtaaat tttattgaag
     1141 aattggataa atcttctgca actgctaaac aaaaggaaga tattaaaaaa gattttaaaa
     1201 acagaagatt tccatatgtt agaaatagtg gtaagtatgg attaaacacg agtttagaaa
     1261 atatggaaat aaatgtaaaa aacatagttg atactgtgat taaatcgaat atagaaatag
     1321 ataaaattga tttagaacaa tatgaagaaa aagatagtgt atgtaatgtt tgtaatataa
     1381 ataaaacaac aaaactagat attgatttaa gagagagaaa ggactctaag tataactttt
     1441 tatttagagg tgcagaaaaa tcaggcttta aaagaagtgg acaagttgaa agtaatattt
     1501 gttttgagtg tgaatttttc aacttaatgt gtcttttata tataaattta aaaagaccaa
     1561 tggtttttgc atatacgaat gatttaaggg aattagcatt tttaaatcat aagataatgc
     1621 ttaaaagaaa aatgtattca gataaatcat tttataaaaa acttttacat gaaaaaataa
     1681 gttcaattag actatatagg tttgatattg atacgaataa aggtataatt ctaaagtttg
     1741 attctattat agagtataaa gaattactaa aaaaaattga acttatagat attatagata
     1801 attacaattt ctcaagagag ccagggaaca ctaaaaattt aggtaaaaaa atgattgata
     1861 atgggaattt atcaaattta aaagaattat tacttgacaa tataagtttt ttaaagccat
     1921 caaatggaac ttctcgagaa atggattttg tatctagttc atataatatc ggcttatata
     1981 taaaattgtg ttggattgta gatggagggg atgagtataa aatgaaaaac tatacagaaa
     2041 gtaatttaat atattcaaga gtaggtaaag acttatttaa taaaatgaca gatgaatcca
     2101 gaagaaaaaa tttttctatg aaagtgattc aactacttaa atctaatgat agaactcagt
     2161 tatttcaaac cataatgcat gtgttagttt ctaatggaat cttaatagga gatgggtttg
     2221 tagaaggtct aatgcagagt tctgaattag aattaaatac aaatgtaggt ctatttattc
     2281 aagaaataat gaaataaaaa gggggaaaat ttaaaatgaa tgaaaaaaga gtaaaaggag
     2341 taacattaac tatactgaca gaaagcccag ttccactttc atatgaccaa ggttatggaa
     2401 attatacacc aataaaaaaa gaacaatata gagaaaaaat acatgcaaaa actagtatag
     2461 ctacaataac atatgactta agaagaatgc tacatcaaga atatggttgg aatttaagta
     2521 atattatttt tgggaaaaaa ggaaatatat atccatctat taagaaaaat gtaggatgtg
     2581 tagatgaaaa tggattagag actgatgtat ttggttattt gataccactt aaagataaag
     2641 gttctataag taaagcttct ccacttagaa taataccttt taggtcatta aatccatata
     2701 taggttcaac acagctaata acaaatagag gttttttaag tagcgaattt ggtagaaaat
     2761 attatgatga gaaggaagaa aatgaagtac ttagagatga aaactttcca acaacacaag
     2821 cattggcaat agaagagact ttatcagatt actacgttta tacaataaca ttggagcttg
     2881 atagaatagg agtagtagaa gtagaagatg ggaagttact tttaccagaa gaaagaaaat
     2941 ttatgagtaa ggaattaaga gaaaaggcag taaaagatat attagatgca attactgtgt
     3001 ttacaagaaa cataaaacat tcatcagtac tattaaaacc acttgcagta atgggtggag
     3061 cttttgataa agttgtaccg tttttttggg atgatgtaga ttacaatgct gatagtggtg
     3121 agataaattt agagggagtt atagaaacta tagaaagtta tagccttaaa gaaagtaata
     3181 caatacttgc tattaatgac agattaaaaa tttctaataa aaaggaatta aataagttta
     3241 atttaagtaa ataccctgta aaagagatta aaaatctagc agacagattg gaaattggag
     3301 aagataatat gtggtattta aaagagtagg aggttttttg aattatgaaa gtattacaat
     3361 gtaaacttaa gcaaccaact gctcactata gagacccaaa agtatttcaa aatgaatata
     3421 taagtacttt aaatttacca tctaagacta caataatggg gatgataacg tatttatgtg
     3481 atagaagatt aaactctgat atagatatag gaataattgg aacacatcat catagagaac
     3541 tagaattttc aagaggagag aatattgatt tttggaatga atatacaaat atgagaaaag
     3601 gtaaagataa agaaaagttt ttgcttaaag gaaactacta tgattactat aaagaacata
     3661 aagctcaaaa tagcatatta aactatgaag ttcttaaaga cgtagaactg actatattta
     3721 tttcttgcaa ggatgatgaa gaacttgaat ttattagaaa aaagcttgaa agtccatgta
     3781 aatatgcaaa tttaggaaga aaagaagatt ttgtaatacc aagtgaaaaa gggtgttttg
     3841 tgaaagaagt tgagttaaaa gaggttatac ctatgaatac tcgtgatgct ataaaagaaa
     3901 atataaaatt aaagaataca tatgtaagag ttgacttaag agataaagag aatgtcgaga
     3961 ctataataaa tcaaggtgta ttgattgcat tgcctcataa atataaagat ttagaagcaa
     4021 atagagacga tagagtttat gagttttgcc attatatata tgttgataat gatggtatat
     4081 atcctaaaaa tattaaggta aatgtatgta ttgatacaaa agaagttttt acatggcttt
     4141 aaattatttt gaaagatagg tgtttatcat ggaaaatatc atgcaaaaag aaatattagc
     4201 taagtcatac aatttaagaa ctaatcaaca agagcaaaca ttagttgaac atattaagga
     4261 tttatttgaa gtattagaat ctatattaga actaaatcta tattcagata aagatgtaga
     4321 gatattgaaa atatgttgtg ctttgcacga tttaggaaaa attaattcga ttatgcaaca
     4381 aaaaatggag attaataata aaatatcgta tagttgttca gaagaagaga ggaaaaagtt
     4441 agagtctgac aaaaaatctt taaaaaagat agcaagacac aatatatttt ctggagcatt
     4501 tttaaaagat atattagaaa aaatgaactt gtcagaagaa gataagttat atatatataa
     4561 aagtataatg ttacatcatg gaaactatga agattatatg aggttaagta ctagtaaagt
     4621 tcaagaagaa atttatgagt atattgaaaa aggcatttta gaaaaagaag agtttaatct
     4681 gaaagatata gaaagttata taaatgacat tttaaatgta gattttaaat ttggtgaaga
     4741 tgtattggat tatgattaca tagataaatt aagtgaaagt atgtttatag acagtgatta
     4801 taacaatggt caaatagaag attcagtttt aaattataga aagtttaagt atattttata
     4861 taaagggatg ttgaatttaa tagaccatag tgcatcaagt agacagaaag gtataaaatt
     4921 ttataacgat tttactgatg aagaaattga taatatgatt ttagatgaga tatataagag
     4981 tcagggtaat ttagaaaaaa ataatataga gttcaatact atacaaaaaa ggttgagaga
     5041 actttctgga agaaatgttc tgactgttgc atttacaggt tcaggaaaaa ccgctgcaga
     5101 ttatagaaag acttttaaaa gaaaattctt tttagtacca aataaaatat cagcagaaag
     5161 tttttataga aaaaatattt ttcaaaataa aaatgattta aatacaagaa atagtaatga
     5221 ttatattgga ttacttcatg gagatataaa cttatactca gagaatgaag ataatggaga
     5281 acatgatttt gtattgacat taagggatat agatttgagt ataaactttt gtaaaccttg
     5341 tgtaattgca acagttgacc agttattact tagtatgttt aaatttccgg gatatgaaaa
     5401 aatatttgca gctgtaaaga atgcatctat aactgttgat gaggtacatt tattagaacc
     5461 aaagatgttt ttgattttga tatattttat gcagtttgca tgcaagtatt tagatgttga
     5521 ttttcattta atgacagcta cacttccaaa atcatataaa gagcaaatga taaacaaggg
     5581 aattattttt caagaagaaa gtaatgaaaa tgttactgat aaaggagaaa tagcgtttat
     5641 tgagagcaac aaggaagaaa acatttgtga aggtaaagat gtaaaggttt cttttataaa
     5701 ggaaaaagaa atcaagtcaa tagttgaagg tgctttagaa aataaacaaa agattcttat
     5761 aataaagaat actattgatt cagtaaatag aacatatgag tttttaaaag aaaatttatc
     5821 agataagtat agtggtgtag atattgatgt tttgcatagt agatttaaat tcaaagataa
     5881 aaaagagaaa tatagtaaaa tattaaatgg aaagggtgat atttggatat caactcaatc
     5941 agtagaaata tccttggatt tggatttcaa tataataata agtgatttag caactatgga
     6001 tagtttgata caaagaatgg gtagatgcaa tagaaataat aaatatgaat atggaaactt
     6061 ttatattcta cctagtgaag ataaaattta tgataacaaa cttaagaaca caactaaaag
     6121 catcttaaat aacgtaataa aaactaactc tatttttaca atggggatta gaaaaactat
     6181 tttggatgat tactatgata atagtgtagt caaaaaatat tttgaagata attttataag
     6241 ttgtgataaa gaaattaaga atatttatgg tataaataaa gaaatttttg atggattgga
     6301 tttaattttt aattttgaac cttataaaaa tattgttgat agtaagaagg aagcagctaa
     6361 aatttttaga gatgttgatg ttagttacaa aattattttg gaagaagatt tttataagga
     6421 agatagggag ttacaacaag attcgattca agtatcaggg tttatattta atagattata
     6481 ttattataga ttaataagca aagtagaagg atacatggta ctaaaatcta gtagtaagtt
     6541 tgagtataat agtactgtag gcttaatttt aaagtgagca tatgtttaaa tataatatgc
     6601 ctttatacat tggaaataca aagagcacta atgtaagccc actgtaaaaa ctagtttttt
     6661 aaaagaaaaa taagttgtgc aatagagtgt tcacacgtgt atatatagca aatttggggt
     6721 ttaagattaa ctaagtggat ttcaggtaca tcatgaaaat aattataacc tggagatttt
     6781 gtatgtttaa tattaactaa gtagatttca aatattgata tagtagatat aatagaaatt
     6841 ttatgattag gtttaaaatt agctaatcga attttctaat attctgacta ttatataagt
     6901 atattattat cttgaattta aaaccaataa tataaaacaa caaaatatta tatttatgat
     6961 ataataaaag ttatggaaaa ataggaagag tactatagag aagagaggta aacttatgaa
     7021 taattggata gaagtaacta taaaaacaac aacagaagca gttgagccta taacgaatat
     7081 actatatgaa caaggagctg gaggagctgt aatagaagac ccaaaagatt ttttattcca
     7141 aaagaaaaat gaactagatt gggattatgt tgaagaagaa gtatttaaaa agaatgaaga
     7201 agatgatgtt cttataaaaa cttacgtttc tgaagaaaaa aacgtgatgg aatttgtcga
     7261 aataataaag caaaaagttt taggcttaaa agattttggt atagatatag gtgaaggaag
     7321 tgtatcatta gaccaagtaa atgaagctga ttgggcaaat gcatggaaag catactacaa
     7381 accaacaaaa gtaggacaaa gggtagtagt aaaacctaca tgggaagatt atgctatgca
     7441 agatggggat ttaatcatag agcttgaccc tggaatggca tttggtacag gtacacatga
     7501 gactactagt atgtgcatta gagaattaga aaagtatgtt aataaagatt ctaaagtatt
     7561 tgatattggc tgtggtagtg gaatccttgc aatagcagca gccaaattag gagcaaaaga
     7621 agttgtagct gtagatttag atgaagtggc tgtaaaagtt gcaaaagaaa atgttcttga
     7681 aaataaagtt gaaaaaagtg tatctgtaat gcatggtaat ttaactgatg taataaaaga
     7741 taaagcggat gtaatagttg caaatataat agctgatata ataaagatac ttgcaaaaga
     7801 tgttcaaaat tttatgaaag aagatgctat atttatatct tcaggtataa ttttggataa
     7861 agtagaagaa gtaaaagaaa gtttaattga aaatggattt gaaatagttg aagttcaaaa
     7921 attaggtgaa tggtcagcaa tagtttctaa gcttaaaaat taagggatat ggtgacgtat
     7981 aatggataga ttctttgttg aaaaaaataa tataaatcta caagataaaa cttgcactat
     8041 agaaggtgaa gatgtaaaac atatttcaaa agttttaaga tataagccag gtgagaaact
     8101 tgagatatgt gacaagaata ataatgagta tatttgtgag atagtgaata tagataagag
     8161 tatagttaac ttaaatattt tagaaaaagt cgatataaat agggaatcag aacttaaaat
     8221 aaggttatat cagggacttc caaaagctcc aaaaatggag atgatacttc aaaaattaac
     8281 tgaagtaggt gtagaagaaa taatattagt tcaaactaag agaagtgttg ctaaagttga
     8341 tgacaaaaaa gaagataaaa aatttgaacg ttgggaaaga ataatttatg aagcagcaaa
     8401 gcaaagtaaa agaggtaaga taccaaaatt aagaggtgtt ttaactttta aagaagcttt
     8461 agaagatatg aaaaaaaata atataaatat ttgtccttat gaaaacgaaa gaacagttcc
     8521 aatgaaacat gcactacaaa attgtgactc taatatagat agtgttggaa tttttatagg
     8581 tccagaaggt ggattttctg aagaagaaat agaacaaata caaaagaata attgcaatgt
     8641 tgtatcacta ggacctagaa tactaagaac tgagacagct tctgttgtag catcaacaat
     8701 agctttgtat gagctaagtg atttaggagg agaaaaataa attgaaaaaa gtagcttttt
     8761 atacacttgg atgtaaagtc aatcaatatg aaacagaagc tatgctagaa ctatttgaaa
     8821 aagatggcta tgaacaagtc aatagtgaag agtatgctga tgtttatgtt ataaatacat
     8881 gtacagttac tcatatgagt gatagaaaat ctcgtcagta cataagacga gttaaaaaga
     8941 agaacccaga cgcaataata gctgttgtag gatgctattc tcaggtatct ccagaagaaa
     9001 ttttggatat agaagaagta aatttagtca tgggtacaaa tgatagaaga aagattgttg
     9061 aagaaattaa aaagataaat tcaagtaaga aagttagtac agttgatgat ataatgaaag
     9121 ttaaagcttt tgaagaaata gaaatcagcc aaactaatgg aaaaactaga gcatttatga
     9181 aaatacaaga tggatgtgac agattttgta cttattgtat cattccttat gcccgaggac
     9241 gcgttagaag tagagatatt gatagtatag tcgatgaagt gaaaaaattg gctaataatg
     9301 gctataaaga ggtcgtatta acaggaatac atgttgcttc ttatggaaaa gatttaaagg
     9361 atagggatat taaacttctt gatgtaataa aacaaataaa caagatagaa aaaatagaaa
     9421 gaattaggct tagttctgtt gaaccaattt tatttacaga tgaatttgta aatgaagttt
     9481 taaagatgga taaagtttgt cctcattacc atttgtcact tcaaagtgga tgtgatgaaa
     9541 ctttaaaaag aatgaataga agatacacaa ctctagagta caaaactatt gtagatagat
     9601 tgagaagtaa aatgccagat gttgcaataa ctacagatgt aatagtaggt ttccctggag
     9661 agacaaatga agagtttaaa aaaacgtacg agtttttaaa agaaatagag ctttcacaaa
     9721 tgcatatttt taaatattca ccaagaaaag gaactccagc tgcaactatg gaaaatcaag
     9781 ttgaccctca aatgaaacat tttagaagcg aacaactttt aaatttgagt aaagtaaatt
     9841 ttaataaatt tgcaactaaa tttatcggcc gtaagttgga tgttttattt gaacaaaatc
     9901 tagaaggcaa taaatatgag ggattaactt caaattatat aagagttgtt gttgaaagtg
     9961 acaaaaatat acaaggtcag atattaaaag tgaaaataaa tgatgtaaaa gatgaatatg
    10021 tagaaggaat tttgctataa catgtagaaa ttataatatt tataagatag gaggtggaaa
    10081 gaatggattg tattttttgt aaaatagcga acggagaaat accttcaact aaagtttatg
    10141 aagatgatag agtcttagcc tttaatgact tgaacccagt tgctccatat catatattag
    10201 ttgtacctaa aaaacattat gatagtttaa ttgatattac tgataaagag atggacattg
    10261 tgtcacatat tcatgttgtt attaataaaa tagctaaaga gaaaggtttt gaccaaactg
    10321 gattcagagt cataaataat tgtggaagtg atggagggca agaagttaaa catttgcact
    10381 atcatatttt agctggtaaa aagcttccta attacgaagc gggacaaaac taaactaaat
    10441 tattgaaaaa ttgagttcct tcttgataaa aatacttgat aaaagtaaaa atttagttta
    10501 taataaacaa agtgttaggt tgtaatgcat attatgcaaa aagaacatag ttacagtccc
    10561 agcataattg cgctattgga gggagggaaa aagaaatgtc agaagtaaga gttagagaga
    10621 atgaaacatt agacagcgct ttaagaagat tcaagcgtca atgtgcaatg tctggcatca
    10681 tgtcagaagt gagaaaaaga gagcactatg ataagccaag cgttaagcgt aagaaaaaag
    10741 ctgaagcagc aagaagaaaa aacgctaaga aatagtagta aataagaata aagaggtgaa
    10801 ggggatgtcc cttaagcaaa agttacaaga ggatttgaaa tcttcgatga aaaacaaaga
    10861 tacagtgaga aaatctgtag taactttaat aagagcttct ataaagcagt atgaggttga
    10921 taatagggtc gagcttgatg aagatggaat tatcgatgta atagcaaaac aattaaagca
    10981 acgtagagat gcattagttg aatttgaaaa agctggaaga gaagacttaa taaaagaaac
    11041 agaaggtgaa attgaagttt taaaagagta cctacctcaa caattaagcg aagaagagtt
    11101 agaagaaatt gtaaaatcta ctatatctga agtaggggca acttctatga aggatatggg
    11161 aaaaataatg tcagttatcc aaccaaaagt taaaggaaga gctgacggaa aacttataaa
    11221 taagttggta aaacaaaact tacaatagat tgatatagcc tagagagaaa tctctaggct
    11281 ttttataatt tttgggaata acgagtcata tttgagcata tctataatca aagaaaattt
    11341 tgaaagaagg ggaaaaattt gattatatca gtaaaagaga ttaggaattt tttgataaac
    11401 atatttatac cactaataat aggttactta agtagcattt taacaatgat tatcagtgga
    11461 acagatattt caacctatta tttacagctc acaaagccaa gctttgcacc accagctttt
    11521 atatttccta tagtttggac tatattgtac atattgatgg gtatatcttc atacctaata
    11581 ttaagaaagg gttacaactt acctaaagta agagatgcaa ttttttatta tggattacaa
    11641 cttgtattaa actttatttg gagtatacta ttttttggat ttggacttag atttacagct
    11701 ttgatagata taataataat gattttggtt tctataataa tgatttcgaa gttttctaaa
    11761 atagataaga gatctggata cataaatttg gtttatttaa tgtggcttgt ttatgcagga
    11821 tttttgaact attttatatg gtttattaat aaatagaatg taaagatttt gtaaattacc
    11881 ctgtactttt aataatatca taacaaacga aaaataaata gactattaaa aataatcatt
    11941 ttcatataca ataatattaa tttaaatata ataaatttat aaaaattgta tttaaagatt
    12001 aacatattaa agtattagaa ttggaaaggc ttgaagggag aggtttttat gcaaataata
    12061 gtatctggga gacaaatgaa attaactgac ggaataaaag gatacgtaga tggaaaatta
    12121 agtaggttag aaaaatacct tgatcctgaa tcagaagtga aagtaacagt aagtgcgaaa
    12181 aaggatagac aaaaagtgga agttacaata attcctatca atggtcaaat aataagagca
    12241 gaagacgtag aagatgactt atatgcagca attgatattg tttgtgacaa attaagtaga
    12301 caagttgtca aatataaaac taaagttaaa gataaagttc aaaataataa gagcataaga
    12361 tttgaaaatg ttgactttat agataatagc agtgaatttg atgattatga tgatgaagaa
    12421 tatgaaaata tagttataga aagaagaaag aaatttaatg taaaacctat gagttctgaa
    12481 gaggctatac ttcaaatgga actagtagga cacaatttct atatgtttag aaatcaagat
    12541 aattttgaaa taaacatagt gtataaacgt aaagctggtg gatatggttt aatagaacaa
    12601 gactaataaa aaattgtata cgtttagatt ttatataaga aaaaataaag aggtaatcat
    12661 gttgattttt tatcaatatg attacctttt tattgttcaa ataatatatt agatattagg
    12721 tgtttattat ataaaaattt taaaactaat ctgttacaac atcaataaag tgcataaata
    12781 cctatttcaa gcataaaatt aattaagggg gtaatgctta tgttagaaat atccactgat
    12841 ttacaagtaa atcaaccagt tattactgtt acaagtaata cgtttattag tatagaaaat
    12901 tatctatcaa tattagaata tgaagttgat ttaataagaa taaagactaa ggttaaaaca
    12961 attaaaatat ctggggataa actttcactt aaatatatta ctgatagtga gataggtata
    13021 aaagggatta tctacaatgt tgagtatgtt gattaggagg agatacactt gataagtttt
    13081 ataaggggat actatgttat agttgtggaa ggagtaggac tcgaacaatt tttaaatcat
    13141 cttataagaa atggtataag tgtttacaat gtaactagaa taaaaaatac taaaatggag
    13201 tttcatatag atagacaaga tataaaagaa tttaagaatg tttatagagg tagtaagttt
    13261 gatataaagg taaagcaaaa aactggggtt ccttttatta tcaaaagagt ttataagcac
    13321 aaaggtatgt ggatttgtgc tcttgtatcg ttatttttat tgatgtcgac atcacagttt
    13381 gtgacagatg tatatataca atctcctgaa ggtataaaaa aagaagctct tagaagtgag
    13441 ctttataagg ttggagtaag accaggagtc tataagaaga gtattgatag aaaagaagtt
    13501 agagaccata tgatgtcgaa atttaatgat gtggcatatt tatctatcaa tgtgaaagga
    13561 acaaatatat ttgttactgt tacaaaaaag gcagaatccc taaaatctac agaccaatca
    13621 aattattgta atgtaattgc tttaaaaaat ggtataatag aaaaggtaat ccctagaagt
    13681 ggtaaatcag ttattaaatc tggagatata gtccaaaagg gagatgtctt gttaaatgga
    13741 gctaatacca agtcaatacc agaagtatgg gcaagtactt tttatgagtc cacaaaaaag
    13801 gcaagttatg tagatactgt aaataaaaaa actggagaaa agaaaaatat atatacacta
    13861 agtttttatg ataaagagtt tacaatgaga aaaaatataa aatataaaga ttatgttgtt
    13921 gaaaataaag aaaaaaaact atcaatagga aactatactt ttccaataaa gataaaaacg
    13981 agcacttttt atgaaacaaa aaaggttgaa gtaaaaagga ataaagaaga gttaaaaaaa
    14041 gaattatctg aaaaagcttt aaaagagtta gaatacataa ttccagcttc ggctagaata
    14101 atagatgtaa aacataactt taaggttaat aaaaatatgt tagaatattt aataaccgtt
    14161 caaactagtg aaaatattgc taaaatttat cctcttagta aatcagaagc agaaaggttt
    14221 ataaaggaag aaagtaaacc agatgaaggt gaagaggaaa ttccttccaa tccagaaaaa
    14281 agaccattaa atgatataag aaatgagttt gatgaggata ataaggataa caaagaacaa
    14341 aacaattctg atgaaaataa tagtaatcaa aatagtaata gcaataacaa ctaataaaat
    14401 taaacttaaa atcttaggag gaataattca attgataata caaaagaaat ttacaatagc
    14461 agatggtaac tttgaaagag agttatttgg caactttgat gaaaatgtaa aattaataga
    14521 gaagacttta aatatagatg taatacttag agaaggtaat ataattttaa ttggagaaga
    14581 aaaaaatgta gattctgcat taaagcttat gaatgaatta caccagactg tatcaaatgg
    14641 taagcattta gataaacaga gtatttctta ttcattatct cttttacttg aaggtagtga
    14701 acaaaaaata aaagaacttg aggggacaat cgttataact caaagaggta aagctgttca
    14761 acctaaaact ttaggtcaaa aagaatatat aaaacttata gaaaataatg atataacttt
    14821 tggcgttgga cctgctggaa caggaaagac ttatcttgct gttgctatgg cagtaaaagc
    14881 ttttaaaaga gatgaagtaa gtagaattat acttacaaga ccagctgtgg aagcaggaga
    14941 gagtctaggt tttttaccag gagatttaaa ggacaaagtt gacccatact taagaccact
    15001 atatgatgcc ttatttgaaa tgctgggtgc tgataaattc aataagtatc tagaaagagg
    15061 tactattgag gttgcaccac ttgcatttat gagaggtaga acacttgata attcatttat
    15121 aatattagat gaagctcaaa ataccacttc tgaacaaatg aaaatgtttt taactagact
    15181 aggatttggt tctaaagctg tagttacagg tgatgtaact caaacagatt taccacaaaa
    15241 taagaagagt ggtctaatac aagctacaga gattcttaaa ggtgttccag gtattgggtc
    15301 tataatgcta acagatagag atgttgtaag acatgagctg gtacagagaa taataagagc
    15361 ttatgagaag cacgacaaaa gagaagaatt taaaaaagaa gagcgtaaaa aagcgaaaat
    15421 gcaggaaaag actttcaaaa gaaagtaaaa gtgtagtaat atagatatat agcattatta
    15481 atgaataaaa agtaggtgta gtgaatggat ttgatactag atgatagaca agataaatta
    15541 gaagtaagtg aggagttact tgaaaagata aaggatataa tcctagaatg tttagattat
    15601 gaaggatatg atgataatta tgaagtgagt ctttcttttg tagataataa agagattcat
    15661 gaattaaata gagaatatag aggagttgat agagtaactg atgttttatc atttcctctt
    15721 ttaagtgatg attttgaaga tgttgagtta gaagaagaat cattaggcga tatagtagta
    15781 tctcttgaaa gagccttaga acagagtata gagtataacc atagttttga aagggaagta
    15841 tgttttttaa tatgtcatag tatgtttcat cttttaggat atgaccacga tacagatgaa
    15901 aatacaaaag aaatgagaga aaaagaagaa cacatattaa ataagttaaa cataacaagg
    15961 gagtagtttt tatgaaacca gaaaaaactc gtcaaggtat aattaaagcg tttaatgcag
    16021 ctatagaagg gatattgtat acatttaaat ttgaaagaaa tatgaaaata cattatttag
    16081 gttcagttgc tgttcttata ataagtttgt tttttaactt ttcaaaatta gaaatgataa
    16141 tgttgcttat gtccatatgt ttagttgtag ttgcggagat gtttaataca gctatagaaa
    16201 aagctgttga tttagtaact gatgaatatc atgttcttgc taagatagca aaagatgttg
    16261 cagctggagg tgttctagta gcagcactaa attcagtagt agttggatat attttgtttt
    16321 atgataaatt gacagatata tctgggatat taatttataa aataagagaa tcagaattac
    16381 atataacctt gatatgtata ttattggttc ttatagctgt tgtagttgta aaagcattga
    16441 cttctacagg tactccctta aaaggaggaa tgccaagtgg tcatgctgca ttagcatttg
    16501 ctatagcaac tgcaattaca cttatgactg aaagggttgt tgcatctact cttgcatata
    16561 taatggctgt gttagttgcc caaagtagaa ttgaaggaaa aatacatacc ttttgggaga
    16621 ctatcgctgg agctttatta ggtgtgttga tagctatatt agtatttcag cttggaatgt
    16681 tctataatta aaatgaatgt acataaaata tttaacataa aacaaatctg tgctaattaa
    16741 atttttatga tataatgtag agtattaaat aaaaataact tttaattatt gtatacagga
    16801 ggagttgttg tggataacat agaattgtta aggttggcag aagatgccag acaacattct
    16861 tatgctcctt actcaagctt tagagtaggt gcagctcttt taactaagag tggtaaagtt
    16921 tatactggat gtaatataga atgtgcatca ttaggtggaa caaattgtgc agaaagaaca
    16981 gctattttta aagcgatatc agaaggtgat aaggatatct ataaaatagc catagcaagt
    17041 gataactcag aaaataatga gcaaacatat ccatgtggaa tatgcaggca ggtaattata
    17101 gagtttggtt ctgatataaa aataataaca ggatatacta aaggagaggt gtttgaacat
    17161 gatataaaag atttgttgcc aaactatttc tctggaaatg atttaaaata aattaaaaat
    17221 tataaataaa tttaagtaat taaaacaaga agataaaaaa gttaggagac agttaatgtt
    17281 caaatcaggt tttgtcagta tagtgggtag accaaatgta ggaaaatcta ctttaatgaa
    17341 taatgtagtt ggagaaaaaa tagctataat gagtgataaa cctcaaacta caagaaatac
    17401 aatacaagca gtatatacag atgaagagat gcagatagtg tttttagata caccgggtat
    17461 tcacaaacca aaaaataaat taggtgaatt tatggtaaag gcggcaacag aagcctttaa
    17521 aaatgtagat ttaatattat ttgtagttga tgattctaaa aaaataggtc ctggagatag
    17581 aaagataata gaggatttaa gaagtgttaa aacaccaata attttagttg taaacaaaat
    17641 agaccaacta gaccaaaaag atgagctatt tgatataatc aaaatgtatg atagagaagg
    17701 tatttttaaa gaaatagtac caatatcagc attaaaagga aagaatacgg ataccctaat
    17761 aaaagttata caaaattatt tggaagaagg accaaagtac tttccagatt atatgattac
    17821 agaccagcca gaaagagtat taatagcaga acttataagg gaaaaagttc ttcactatct
    17881 taatgatgaa atacctcatg gtgtagctgt tgaaattgaa aaaatgaaag cgagaaatga
    17941 taaggaaata gtagatgtat ctgctgtaat atattgtgaa agagattcac ataaggggat
    18001 aataatagga aaaaatggta ggaaactaaa aggaataggt aaatcagcaa gacaagatat
    18061 agaattactt ttaggttcac aaataaatct tcaattatgg gttaaagtca aagaaaattg
    18121 gagaaattta caaaattata taaataattt tggatataat gataaataaa ggtgggttat
    18181 atggatagga aactggatgc ttcccaagat ttattatatg aagtaaaatc attaattgat
    18241 aataataaag tattggagtt aagagaatta atagaggaat atcatataat tgatatattc
    18301 gatataatgg aaaatttaga ggaagacatg aaaattcaat tatttgaagt acttccttta
    18361 gatatggcat cttctatatt agaagaaggt agtgtagagt tttttattag tattttatct
    18421 aaactggatg tagaacactc gaaaaatata cttgaactta tgtctcttgg agatatggca
    18481 gacaagttga gtgaacttga agaagaacaa agagaacaca taataaatct tttgaatcaa
    18541 gagaatgccg attatgtaaa agagttactc ttctatgatg aagattctgc tggtggaaca
    18601 atgaccactg gatatatttc tataaataaa gatatgacag ctcttgaagc tatagaccat
    18661 atgagggaag aagctgaaga agctgaaact atttattata tatatgtggt tgatgatgaa
    18721 gaaaaactag ttggagtatt atcattaaga gaattaatag tagctagaga tgcaaatata
    18781 gtagaagatt tgatgagtga aaatataatt tctgtttatg tagatgaaga tagagaagaa
    18841 gcagtaagat tggtatctaa atacaattta atagcaattc cagtagtaga tagacaagaa
    18901 aaattaaaag ggataataac agtagatgat ataattgatg taatggaaga agaagcaact
    18961 gaagatatgt ataaatttgc aggaagttca gaacatgaaa gagaagttgc tgaaaaagaa
    19021 aaccctacat tgaaagagca aataatatca gcacttagag gaagattacc atggttaatt
    19081 attaccttag ttggagggtt gttggcttcg ttaatacttt ctaacttaga ctatataatg
    19141 aaccctgtat atgctccatt agtatttttc atacctgtag taattggcat gggtggaaat
    19201 attggaactc aatcatcatc tgttacagta ataacattat ctaataagga tttaaatttt
    19261 agcaatgtgg ttagagaagg tattgtagga attattacag gtcttttgtg tagtataata
    19321 acaggtattg taatttactt tgttatgaga aagttagaca ttgtattaat tgtttcaata
    19381 tcattattta taaatatggt tttgggtgca acaataggtg cgtttatgcc tgttttatta
    19441 aaaaaaatgg atgcagaccc atctacagtt tcatcaccaa ttatatctac agctcttgat
    19501 ataactggca tagcagttta ctttataata acaacagcat tattgtcaaa aattgtttaa
    19561 taactttatg tatgatttat cctcttctta ctaaaaatat aagtataaat gtaagaaggg
    19621 ggttttttaa aaatgaacaa tatcagttgg gaagttttta aaaaaacagg tagtatagat
    19681 gcatatttat atttctgtga ttgcaaaaac atacatgaag aaattgaaga agtaagggag
    19741 aaaaaagaag acgatgataa tcctgaacac ccaggggata gtacttaagg ctataaggta
    19801 taaggaaagt gacataatac ttacactatt tacaagaaag cttggaaaag tatctgcaat
    19861 agcaaaagga gctaaaaaaa ataagagctc tttgctttca tcatcacagt tattttctta
    19921 tagcaatttt accttaaaaa aacaaggtaa tatgtacaag gttactcaaa gtgaaataat
    19981 aaaaagtttt tataatatat cctatgatat agaagcattt tcttatgcta catatattac
    20041 aaaattagtt gaaaattcta tacttgaaaa tcagactaat aataggctat ttatattact
    20101 tgcacaaact ctgtatttgt acacacagga taatacagat aataggttta taacagcagc
    20161 attcgagtta aaatttttag actatatagg atttaaacct atagtaaata aatgcattaa
    20221 ttgtgaatgt aaaattttac aaaattctgt gtttaatatc tatgaaggtg gtatactatg
    20281 tagtaagtgt agtaaacttt ttgataataa tataaaatta gacttaacaa ctgtaagtct
    20341 tatggaatat gtattaagaa atgatatttt aacatgtagt aaagctaaag tatcaaaata
    20401 tataacacat gagcttgaga atattctaga caagtatttg aaagtttatg ttgataatat
    20461 taattttaaa tcattacacg tattgcaaag tgtaaaaaat aataagggag tggataatga
    20521 tgagtagtaa tataactatt gaaatggttg attcagtctt tgaaagagtt ccaggagcaa
    20581 cttatgcaga agcaaaagag gcattagtaa tgtgcaatgg agatgtaatt gaggcagtaa
    20641 tatatttaga aaataaaaaa aatacttgta attgtaaagc aaaatctgct aaagaaacta
    20701 tggaagaagt atttggtaaa gatggagaaa atataaagtt ccaattaaaa gagcttctta
    20761 gaaaaagtag tgtagtgaga ataatagttg aaaaagatgg aaaaactatg atgaacattc
    20821 ctttaacagt tggagttgtt ggattagctt ttgtaccatt agctacttta gttggattat
    20881 cagctgctgt tataagtaaa tatcgtataa aagttcaaaa tgaagaagat ggagaaattg
    20941 tagacttagg tgagttgaat gaagaaaaac ttcatgtttt gaagaatatg ataactaatg
    21001 cagcaaaaga tgtaaaggat gtagtagttg acaaaaaaga agatgataag gatgtaactg
    21061 ctgaccttat gaaagaagaa tctgaaaaga ataaagaaga cgaagacgaa aataaataga
    21121 tataaagtga cttttaaaaa atgaagagaa gataattata agaattatcg ctaacattga
    21181 caaattttat agaatttgat attctaaaag ttgtagaaga actattaaaa tagcctttcg
    21241 tgtagacgag aggctttatt gttataggag ggatttttat gaattttcaa gagatgatac
    21301 tggcgttgca aaaatactgg tcaaagcaag gttgtatcat gatgcaaccc tatgatattg
    21361 aaaaaggtgc aggaactatg aatcctaata cttttttaag atcattagga cctgaacctt
    21421 ggcaagtatg ctatgtagag ccttcaagaa gaccagcaga tggaagatat ggtgaaaacc
    21481 caaacagact atatcaacat catcagttcc aagttatact aaaaccttct ccagataata
    21541 tacaagagtt gtatttggag agcttaaaag aaattgggat tgacccaagt gagcatgata
    21601 taagatttgt tgaagataac tgggaagctg ctacagttgg tgcctgggga cttggatggg
    21661 aagtttggct agatggtatg gaaataactc aatttacgta ttttcaacaa gtaggtaata
    21721 ttgaatgtga gcttgagaca ggagaaatta catatggatt agaaagatta gctatgtaca
    21781 ttcaagaagt tgatagtgtt tatgacttaa aatggaatga taaaataact tatggtgaag
    21841 tatttaataa agctgagtat gaaaactcaa tgtatgcatt tgaattatgt gatgcagata
    21901 tgttgtttaa tctgtttgat atatatgaaa aagaagcatt aagacttatg gaaaatggac
    21961 ttgtaatacc ttcatatgac tatgtgttaa aatgctctca tgcatttaat acattggatg
    22021 caagaggtgc aataggagtt agtcaaagag cttcatttat aggtagagtt agaaatatgg
    22081 caaagactgt tgcagaaact tttgtaaaac aaagagaaga aatgggattc cctcttttaa
    22141 aggacggtga caaataatga aaaattatct tttatttgaa atcggtgttg aagaaatgcc
    22201 atcaagattt gtaggcagca cactagaaca attaaaaaac aatcttagca aattatttga
    22261 tgaaaataga atagcttttg ataaaataaa tgcgtatggg acaccaagaa gacttacttt
    22321 agtagtcgaa ggattgagtg atagacaaag tgatttagaa gaggaaataa agggtcctgc
    22381 taagaaaatt gctgttgatg cagaaaataa tttaacaaaa ccagcattag gatttataaa
    22441 aagcaaagga ttaagtgaat ctgatatata ctttaaacaa gttggaaaag atgaatatat
    22501 ctttgctact ataaagcaag atggaaaaga aacttcagaa gtactaaaag atatattacc
    22561 agatactata aaatctgtag tattcccaaa agctatgcgt tggggaggaa aaaatcttaa
    22621 gtttgcaaga cctataagat ggatagttac attgttaaat gataaagtat tagagtttga
    22681 tttagaagga atagtatctt ctaatgtaac aaaaggtcat agatttctag gtgaaagtac
    22741 aatagaagtt gattctatag aagactattt tgaaaaatta gaaaaaaatt atatagtttt
    22801 agaccaaaat aagagaaaag aaatgataag aaaacaatgt atagaagtgg caaattcttt
    22861 aggtggagaa gttgaatttg atgaagattt acttgaagag gtaacttact tagttgaata
    22921 tccaactgct ttttatggag aatttgatgt agattatata aaactaccaa aagaagttgt
    22981 tataactcct atgaaacaac atcaaagata ttttccagta cttaaagaag gaaaactgtt
    23041 acctaacttt atagctgtta gaaatggtga ttcttataga atagacaacg ttaaagctgg
    23101 aaacgaaaaa gttttagaag caagacttgc agatgcttta tttttctata gagaagatac
    23161 taagagaaac ttagaaagct atatagaaaa attaaaaact gttgtattcc aagtaaagct
    23221 aggaactatt tatgacaaaa ctttaagact tgaaaaatta agtgctgata tacttgacag
    23281 tttaggttta gtagatgaaa aggcagatac tataagagct gctaaattat ctaaggcaga
    23341 tttagttact ggaatggtag gagaatttga tgaattacaa ggttttatgg gaaaagaata
    23401 cgcaaaagtt ggaggagaga acgatgttgt aagtgaagct atttttgagc attatcttcc
    23461 aagatttgca ggagatatac ttcctaagac taacgcaggg gttgccttat caatagctga
    23521 taagttggat tcaatagtag gtttctttgc tataggaata caaccaacag gttctcaaga
    23581 cccatatgct ttaagaagac aagctttagg tatacttagt atacttatgg acagaaaagt
    23641 tgctgtggat ataaaagtac ttattgaaca tgctttagat aattattctg aattagattt
    23701 taatagagaa gaagttgttg aacaaataat gaatttcttc aatgagagag taaaaaatct
    23761 gtttaaagat ttaggaataa gatatgatgt tgtcgatgct gttttaagtt ctgatataaa
    23821 tgatgtttct gacatgcata tgagagcttt agagcttaat aattggctag aaaaagatga
    23881 attagtggag atgcttactg catttaacag agtttctact ttagctcaaa aagcagaaag
    23941 cgataaaatt gatgaatctt tattaaaaga agatgctgaa attaagcttt acaatgaatt
    24001 taaacaagta aaggtaagag ttaagcaatt attaaaagat aagaaatatg gtgttgcttt
    24061 agatgaattt gcatctttaa gaccagtagt tgataattta tttgatacag ttatggtaat
    24121 ggataatgat gaagctataa agaacaatag acttgcttta cttaaacaag tatacgatac
    24181 tatgctagaa atttgtgatt tatctaaaat tgtttataaa taaaattcaa gctatttata
    24241 aataatgagg ctatctcaaa atagagataa gcctcttttt tatttttgaa atgataaaaa
    24301 tatatttaat tgcatacaaa aaagagtacc tcatgaactg aaaagttaat tttgaggcac
    24361 tgctactttt tataagtaaa tgtaataaat catattttat acttatcagt tattttgttt
    24421 aagatgtcat catttgaatt tacccattca taaaaatttc ctgttgaagc gtcagatatt
    24481 ttataaagca tttcaggaat atcgctagct ttaaaatctc caagtgattt tcctaatcta
    24541 gtcttgccta tttcaaagct acctccaaca aataattcaa atgcatctgt agatacacca
    24601 tcaacattct tctttttacc acataaacct atactaccaa cttggtgaac accacatgaa
    24661 tttaaacatc ctgatatata taacttaggt gctttattta aaatttcttc attattctgt
    24721 aatctaaaat aatctatgat ttcatgtaac attttctgac tattttgtat acccatttgg
    24781 caaattggaa cacctatgca agatatgctt tgttctaatt gagaattaca actaatagtt
    24841 ttacttattt ctaatattct ttttgcttca tttccattta aatttaaaat atataatccc
    24901 tctgtcattc ctagtctaat catagggttt tcaatattat ctaattcttt aagtaaagta
    24961 tttaaatcct ttgttaacaa aatacctcca actggatgta tatacacagt gtataaacca
    25021 tcttgttttt gaggtattaa tctggaatct tgtatacata ttttaactcc agatttagag
    25081 tagtctattt cttcaatatt gagttcaaga ccaccatttt ctttttctaa tttatagtat
    25141 tctttaaatt tttttaagaa tagctcttca ccaagtgatt cgaccatata tctaactcta
    25201 gctctgtttt tattttcata attgccataa tccataaaga atttaatcat accttcaaca
    25261 caatataatg catctttcgg ctttataagt tcgtcaagct ctaaagcaac tttgggttgt
    25321 ttacctagac ctccacctaa gaaaactctg aaatattgtt catcattttt caaagtagcc
    25381 acaaatccta agtcttgtat actacaatga gcagtatctg tgtaacaatt agaataagaa
    25441 acttttaatt ttctaggtag atggtatgta gtagcatttt tgataaaata tttatcagta
    25501 gcaactgcat atggagtaac atcaaaggct tcactagggt caactccaga caatggagat
    25561 aatccaacat ttctaggata attaccacca ccacctctag tgaatatatc gttttttatt
    25621 ccttctttca tgatatcgac aatcgaatct atagataaat cgtgtaattg tatagcttgt
    25681 ctagttgtta agtgtatctt atctaagttg tgtttaatag ccatttcata gattttattg
    25741 agttgatgat gagataaaac tccagcagat actctaagtc ttatcataaa agattttttg
    25801 tctctttgag cataaacacc gtatccacca gaaaatccct tatattgcat tttatttatt
    25861 tctccattta aaaattttga agaatattct ttaaaattag gtatttcatt taacaatatt
    25921 tttttaaaat tgtccattat ttcacctcat tattagtctt gtataaaaat atatctattg
    25981 tataatagat atatatatta ttatctagtc aggataaaaa tataacagaa taattctatt
    26041 aaaagtaaga ataataagga catagtgagt attttgtttt tattttacaa attaagtata
    26101 atatttttgt tttataaaat ataattaaga taaatagata attttgcaat tttaatatat
    26161 aatgtttagt agagtgtggg agtagcactt aatatttgca gaaggagttt ttgtatatgg
    26221 gagaaataat aaatgcatta gatagagccc tagacataat tttgctgtta tatcatgaaa
    26281 agagagaaat gggaatcact gaaataagca aggctatggg agtatataaa agtactgtac
    26341 atagaacttt ggtcactctt gaaaataaag gttttgttat acaaaatgca gaaaatggta
    26401 agtattggct aggaataaat ttatatgcaa taggtatggt tgtgggagaa aaaatgtcat
    26461 tgactgaaat cgtaaaacca tatacgaaaa aattaaatca agaatttaac gaagtagtta
    26521 atgtatctat attagaagaa agagctcaag attctccaag aagtattata atacataaag
    26581 agtatggttc aaatcaatta ctttcagtaa atccatccgt tggctcaagt agtgaatgtt
    26641 attgttcggc agtgggtaaa tgtcttatgg catttaatga ttctatagat tttgaaaaat
    26701 atagaaaaac accaatacac aagtatacag aacatacaat tgataattgg gatgatatga
    26761 tgcttttttt agcaaaaata aaagaacaag gatatgctat agatgatgaa gaactagaac
    26821 atggactaac ttgtattgga gcacctatct tagataaaaa caataaagct attgcagcaa
    26881 taagtttgtc aggtccaact ataagaatga gagaagggga ctttgagtat aagattaaaa
    26941 gagttataga aactgcaaaa agtatatctg aactttttag atgatttttt aatctagata
    27001 agaaaaagag gttatattta aattgttatt tgtaaatatc agtttaaata tagcctcttt
    27061 ttctttaatc taaaattaaa tattcttaaa atttaaaatg ttattgaaat atataagcga
    27121 atgtgttatc ttttaattaa gcaataaaaa tagaacaagg ttctatacta tagaacaaaa
    27181 attaatgcat atatagtatt tatataaaat ataaatatta tatatttaaa attaagtaaa
    27241 aatattacat aaaggggaga tttgagaaat ggaaaaagtc aagttgagtg ttgaaagatg
    27301 taagggatgc tatctttgta ttgaagcttg taaaaaagat gcaataagtc tttctgacta
    27361 cacaaataaa aaaggctttg taactattaa agtcgatgaa gaaaaatgta ttcaatgtgg
    27421 cgcttgttat acaatgtgcc ctgacttagt atttgagata ttataaatta tttttattag
    27481 aggggagaaa aggtatgcaa agtttattaa ttaaaggaaa tgaagcttta gcagaaggtg
    27541 ctatacgtgg tggctgtaga ttttatgcag gttatccaat aacaccacaa tcagaaatat
    27601 tagaaatgat ggcatggaga caaaaagaag ttggaggagt atttatccaa ggtgaatcag
    27661 aaatagccag tgtaaatatg gttatgggag caagtgcact tggagcaaga gctatgactt
    27721 cttcatctgg tccagggttt tcattaaaac aagaaggtat tgcatattgg gtatcagctg
    27781 gtttgccagc agttgtagca tgtgtacaaa gatatggtat aggtgatgga tttataggag
    27841 ctggtcaaga taattattgg caagcagtaa aaggtggcgg aaatggagat tatcatttaa
    27901 tcgtgttggc acctaatagt gttcaagaaa atatggatat ggcatatgaa tcttttgaac
    27961 tagctgaaaa atatatgcat ccagtactta tactttctga tgctacaata ggtcaaatgg
    28021 tagaaccttg tatagcacca ccaatgaaag aatacgatat ggataaagct ccatgggctg
    28081 caaaaggaac acctgtagga gaaaaaaata aagtaataac tgatataaca tactttgaag
    28141 accaagatac atggcaaaaa gggtatatag aaaaaatgag aaaagttcaa gaagatgaac
    28201 aaagatggga agaaatagaa atagaagatg ctgaagtggt gtttgtggca tatggtattt
    28261 catcaagaat agcagaaggt gcagttagag atgctagagc aaaaggaatg aaattaggac
    28321 taataagacc aaaaacattg tggccttacc caagaaaggc atttaagaaa ttaagtgatt
    28381 cattgaaggg acttgtaaca gttgaaatga acatgatggc acagatgaag gaagatgtaa
    28441 ttatagcatg tgataataga tttccagtat attcagtagc aacagctcaa tatatggcag
    28501 aagtaaatca attaatagat tttgctcaac agattataga tggaaaagct aagcaagagg
    28561 aggtatttta attatggcta aaaaagcacc agcaataatg atgtgtgaaa atatgttctg
    28621 tggaggctgt ggacactcta tagtcgatag aattattgga gaagtattaa cagaaatgga
    28681 tatatgtcaa gatacaatta tatgttcaga tataggttgc aaccatatgt tccaatttag
    28741 tatgaatgta gatgttgtcg ttccacctca tggtaaaatg ggagcagcaa tggcagctat
    28801 gaaaagagtc agaccagata aatatatatt tacaatagct ggagatggtg gagcttatgc
    28861 aatagggctt ggagaaacta tgtcagctgc tactagaaat gataatgtaa tatttcttgt
    28921 tatgaacaat aacatgtttg caatgacagg gggacaaatg gctccaacta ctgtagaagg
    28981 tcaatataca gcttctactc cagcgggtag aaattacgca gatcatggtt caacatttga
    29041 tgttgtaaaa gttatgggaa atttagatat agcatatcta gcgagaggaa caataactaa
    29101 ccctaaagaa ataaatacaa caaaaagata catcaaaaaa gctctagaaa aacaaaaaga
    29161 aaagaaaggt ttttgcttaa tagaagtgct tgtaccatgt ccaacaaact ggggattaaa
    29221 gccagtagat gctatgaaga gaattgaaaa tgaacttgtt ccaaagtatc cacttggaga
    29281 atttattgat tagggaggaa ataatatgtt gaatgaaatt atatgtgctg gttttggagg
    29341 acagggagtt cttacagcag gaaaaattat aatgtatgtt gcatataagg cagaaaagaa
    29401 aattacatgg ttcccatctt atggaaatga gatgagggga ggaagtgcaa attgtaatgt
    29461 tgttgtaagt gatgaaaaaa ttgcaaatcc ttgtgtaaaa aatccagata tattattggg
    29521 aatgaacagc gtatcagtag ataagtatga aagtttaatg aaaaaaaatg gttatatgtt
    29581 tgtcaatgaa tcactagtaa gtaaggatag aaaatacaga gaggatatta atgttataag
    29641 agtacctgtt actgagatag cacaaaattt aggtaatgaa aaagctgcta atatttgtat
    29701 gttaggtgct atggtaaaga atttggattt atttacaaaa gaagaatttg aaaatggtat
    29761 gtgtgaatac tttgaaaatc aaggcaaagg taaatttaat tctaaaaatg tagaagcatt
    29821 tgaagctgga tacgactacg agtgaatatt ttaaatattt aaaataatta ttgaaatact
    29881 tatttttata tgttagtatt taattaataa aatatagaac gtcgttctgg acaataggac
    29941 aaaatctttg tgcttgaata taagaacgac gttctatgta atagaattag gaggtgttaa
    30001 attgaaaatt ttagtaataa atcctggcgg tacatccaca aagatttctg ttttcaaaga
    30061 tgaaaatgaa attttgaaaa aaaatataac ccatacaaga gaagatttaa aaaatttttc
    30121 taaagtattt gatgaatatg attatagaaa acaactgata gtagatattt taagtagtga
    30181 gaatcatagt ataaattctt ttgatgcagt agttggtcgt ggtggactta tgaaggctat
    30241 aaaaggtggt acttatactg tgagtgaaga aatgattgag gatatgagaa atgaaataaa
    30301 tggggaacat gcatcaaatt taggtgcatt attagctaaa actatagctg atgaaatagg
    30361 ggtacaatca tttgtagtag acccagtctc tgtagatgaa tttgaagatg tatcaaggat
    30421 tacaggaata tcagatatag aaaaagcaag ctggctacat gcattaaatc acaaagctgt
    30481 ttcaagaaaa attgcacaaa aactaggtgg aaaatacgaa gattataact tcattgttgc
    30541 tcatttaggt tcaggaatat cgattgtagc acataaacaa ggaaaaatga ttgatggaag
    30601 tggtggaagg tctgatggtc cattttctcc agaaagaagt ggtggattgc ttgcatatcc
    30661 tcttatagaa ttgtgttact ccggtaaata tactcatgat gaaatggtag caaaagtaag
    30721 ttcgattgga ggcatgtacg actatttggg cacaaaggac atgatagaaa ttgaaaacag
    30781 aatcaagcaa ggtgatgaaa aggcaaaact tataatggat gcattcattt atcaagtagc
    30841 aaaagaaatt tctatgtatg gagcttcact ttcaggcaat gtagatagag ttattttaac
    30901 aggaggaata tctcattcag aaatggtagt taaaggagtc atagaaaaag tttcatatat
    30961 agctccagta gaggtagtac caggggagat ggaaatggaa gcacttgctc ttggagctct
    31021 tagagtactt aatggagaag aaatagcaaa aacttattaa tatttaggag aaggagtatg
    31081 ttaaaagatt ttaataattt attggaagaa gctaaaaagc ttgaacctgt tatagtaagt
    31141 gttgctgttg cagaagacaa agaagtatta aaggctgtga aatcagcaac agatttaaat
    31201 attataaagc caattctcgt aggagataaa gataaaatag aaaatatatc aaaagaaatt
    31261 ggattaaaag gtcatgaaat aataggatgt caaaatcctg atgaatcagt caaaaaagct
    31321 gtagagatag taaaaaataa ggaagctaaa gttcttatga agggattagt aaatacgagt
    31381 gtgtatatga gagctatatt aaataaagaa actggtctca gaacaggaag attattgagt
    31441 ttacttgcag tatatgaatt acctcaatac cacaaacttc tttattgtac tgatagtgga
    31501 ataaatgtat caccaaatct aaatcaaaaa aaagatataa tggtaaatgc acttcttact
    31561 atgaaaagta taggcatgga aaatcctaaa actgcgatac ttactgcaaa tgaaatggta
    31621 gaccctaaga tacaatctac agtagatgca aacctacttg ttgagatgga aaaatcggga
    31681 gaaataccaa attgtatagt ggaaggtcca atagcatttg atgtagcatt tgatgcacat
    31741 gcagcagaac ataaaggtat caaaagtaat attgctggtg atgttgattt actagtattt
    31801 ccaaatatag aagcagggaa tatattagga aagtcatggc ttagatttaa taaagctaag
    31861 tgggcaggta tagttttagg agcaacaaat ccaataattt taggttcacg ttctgataca
    31921 gctgaaatta aaataaattc aatagcatta gcgtgcttag catcacaata agaaatcatt
    31981 attaaggagg ataaattatt atgaaatatg caaaaagaat ggatatggta aaagcttcag
    32041 ctataagaga ttctcaaaag aaaatagctc agaaggtagc aagtggtgga acggttatat
    32101 cttttgctgc aggacttcct gacccaaatt tatttccaat agaagaaata agtgaagtaa
    32161 ctcaaaaagt acttaaggaa agaggtaagt ttgccctagc atatggacct actaaaggtg
    32221 aagatgagtt gttagagcta ttagtaaaaa gaatgaaaga agaggaaaat attgatacaa
    32281 aagcagaaaa tattataata actactgggt cacaacaagg gatagcatta agtgctatga
    32341 ttttattaga aaagggagat gtagtagtta cagaaaatcc aagttactta ggtgcaataa
    32401 atgcatttag accttatgaa tgtgattttt taggagtaga tacagacgaa gaaggaatgg
    32461 taacagatga tttagataaa ttattatctg aaaattctaa cataaaggtg atatatgtaa
    32521 taccaacatt tcaaaatcct acaggaaaaa catggtcttt acaaagaaga aaagatttta
    32581 tggaagttgt aagtaaatat gatgtcatag taatagagga taatccttat ggagaaataa
    32641 gatttacacc agaacctcta cctacactta aatctcttga tactaaagat aaagtattgt
    32701 accttgggtc attttcaaag gtattatgtc caggatttag agttgcttgg atgtgtggta
    32761 atgtagacat catagataag gcagaacttt taaaacaagg tatagattta cagtcaaatc
    32821 aattttctca agtacaagta atagaatttt taaagaaata caacttaaat gaacatatag
    32881 aaaaaataag agaagagtat aaaaaaagat gcttactaat gttggatgct atgaagaaac
    32941 acttcccaga ggaagctaaa tatacagagc cagatggagg aatgtttata tgggttgaac
    33001 ttcctgaaag cataaatgta gatgatttat tagataaagc cattgatgct ggagttgctt
    33061 atgtttctgg agagtctttc tttgcaaata atggtccaaa aaatactatg agacttaact
    33121 atacaacaat gtcagaagaa caaattgtta aaggtgttga gatacttgca gaagttataa
    33181 aaaaagaact caattatgct tgtgaataaa tataaaaagt gagggtttaa atatgggaga
    33241 aaaagaaaac ggtataaagt ttggaaagtt aatgtttcaa ctcgttatta tagcaatatc
    33301 ttgggaatta gtttatatta taccatttat ccaatataca ttatatgatc caatcctaaa
    33361 agcattagaa tgcacaaata ctcaactagg ttttttactt acaatttatg ggttaggtaa
    33421 tatatttgga gctcctatag gaggctggtt agcagataga tttgattata gaaagataat
    33481 tttaggttct gtatttctta atggagtagt atcatttttg tttgcattta atatgaacta
    33541 tccatttgca gttgctactt gggtgggttg tgcaatcaca tcattagtta tgaactatcc
    33601 ttctatggta aagatactta gagttatagg aaaagataat caaggtaagg tttatggatt
    33661 taatgaagct atggttggag tttctggcgt agtaatggga gcaatattct tatatattta
    33721 tacatgcttt gcaactccta cattgggtat gagatgggta atgatatctt taggaatatt
    33781 atcaatagca atgtgtccag tattatggtt tgtaattaaa gatgtagata ttaaagaaga
    33841 aaaagaagaa gcaggtgaaa aaatgtctgc tggtgatttt ataacagtac taaaatcacc
    33901 aaatacttgg ctagtaggaa taagtatatt ctgtgtatat tcattcacag ttacaatgtc
    33961 ttattttaca ccatatataa catctgtact tggaggttct gtagcactat ctggtgcatt
    34021 agcaataata agacaacatg gtctaaaatt gtttggagca ccatttggag gatattgtgc
    34081 agacaaatta aaatctccta caaaagtact tttaccaata tatgtatttg gtatagcagt
    34141 aatagtttta ttcctagtat tacctgcatc aactccaatg actatattca tagctctaac
    34201 atttgtagta ggtatattag gttacatggg aaaaggtata tattatgcag tacaagatga
    34261 agtaaaagtt ccagttaaat attcagcaac tactataggt atagctgcag ctttaggatt
    34321 ttcaccagat gtattccaat ttgcgttaat aggacactgg atagatactt atggcaataa
    34381 aggttacaca tatacattta tattccagat agcaatttta gttattggaa tactatcttg
    34441 tttatatata ttaaaggtta aaaagagaag agcaagtaaa ttagaagctt aaatattcaa
    34501 tttggtgatt aagtacatgt aaatacaata cttattttga tgaatgtgat tgtataaata
    34561 acataaaaaa tatcaataga ttaagtttta taataatgtt tagagaataa aatataaaaa
    34621 tcaaaatgtt atcaagtttt ctaagtttta gcataaagtt acccctaaag gtataaaatt
    34681 gagtagtaat tattatctat tttcttactt acataaacct atttaattta aattctaaga
    34741 gaatttcaaa atagatggca gttgtactca attttatacc tcataataaa tacgaaaatt
    34801 taaaatctaa ctagatacta tttaattata tattaataaa tatatattgt attatttata
    34861 taatagtaat ttcaggcttt tcattatatg tattccaatt tatattgttt gattattgtt
    34921 caagcacaca tcgttaaaaa ttttataaat ttatgtttag atatgattaa tactcttgat
    34981 tttagaaata aatatttgta gattgtagat taaaaataat ataaataaat agaaggtaga
    35041 ttttttagat atattaagat gaagattata taaaatattg aaatatagct gtttaaatta
    35101 ttgtctataa atataaaatg aatggtggtg agttacgtga ccgatttagt taacaccatt
    35161 aatggaattg tttggtcacc tgtattagtt gcaatgtgtt tgtgtatagg attatatttt
    35221 tcgttgaaat taaaattttt tcaaataaga gatgtaaaag aaatgtttac tctcttgctt
    35281 gaaggagata gttctcatgt tgggatatca tcatttcaag gctttgctac atctatggct
    35341 ggaagaatag ggactgggaa tatagctggt gtagctgtag caatagcaat gggaggtcca
    35401 ggagcattag tatggatgtg tataatggct acattaggtt cagcaactgc atttgtagaa
    35461 tctactctag ctcaaatata taaagatgag catgatgggc agtatagagg aggacctcca
    35521 tattattttg aaaaaggtct tgggtggaaa aagtgttcag ttttattttc aatagttgca
    35581 ataataagtt atacattttt tatgcctggt acacaatcaa atactttata tctagcaatg
    35641 aatcaagcat ttggattttc aaaaatgaca atagcagtcg catcttctat tgcattagca
    35701 ataataattt ttggaggaat taaaaggatt ggtttatttg ctgaaaaagt agtacctata
    35761 atgggtggag cataccttat tatgacatta gtaataatta taacaaatat tagtttagtt
    35821 ccagaagcta ttgtaacaat gtttaaatct gcatttggat ttggttcagt ttttggagga
    35881 atgttaggtt cagcagtatc ttggggagta aaaagaggta tatactcaaa tgaagcagga
    35941 gaaggttctg ggacttatgg tgcagcagcg gcagaagtaa gtcatccagc caaacaagga
    36001 ttagttcaag cattttctgt ttatgtagat acattattaa tatgtatggc tacaggtatc
    36061 atgattgtaa taacaggaat gtataatgtt acaggtgttt gcacaacact gccaggtgta
    36121 gaacctgggc cacaatatgt acagagtgca ataaatacat tacatccaca attaggtgat
    36181 atttttatag caatagtttt attattgttt acatttacaa ctttattagc cttttcatat
    36241 atgatggaga ctaatgtatc ttacttagta actagaatta aagcagaaaa atatgaaaag
    36301 tacataatta acgtctgtag atttatgctt atagcatgtg cagcaatgtg ttgttttata
    36361 gaaccactta caagttgggc attaggtgat atatgtatag gtgtattaac atatataaat
    36421 ttaattgcca tctttacact aaaaaaacca gctataaagg catattatga ttatataaga
    36481 cagaaaaaga tgggaataaa aaggagcgat agaactttta atcctataga attagatata
    36541 agaaatgctg agttttggga aaatagatac ttaaaagaga ataagcatga gttaaattaa
    36601 agttataata aaatataaga attactaaat aaacttagtg ggaggtaaga ttggtatgaa
    36661 agaaagaata atacaagtgg cggattcaaa gaaagaaaaa attctagggc tatgtcaatc
    36721 tttatatgat gaaccagaaa ttgctttgca agaatataaa tctgctaaaa aaatagcaga
    36781 atttctaaga gaagagggct ttgatgttga ggaaaacttg gcaggtatgg ctacagcttt
    36841 taaagcaacc aaaaaaaatg gagatggtcc caaaatagca tttatagcag aatatgatgc
    36901 tcttccagga aatggccatg catgtggaca tcatttaatt gcatctatgg gagttggagc
    36961 tggaatagct ctttcaagta tactggatac ttataaggga gaagtcagta taattggaac
    37021 acctgcggaa gaaactggag atggaaagcc ttacttgata gaacatggtg tatttgatgg
    37081 ctatgatgca gcaatgatga tacatccaaa ttcgaaaact tgtgtgacac cagaaattat
    37141 agcaatagga ggattggact ttatatttac tggaaaagca tctcatgcag gagctaaacc
    37201 atataatgga ataaatgcac tagatgcagt agtactacta tataataata taaatgcact
    37261 aagacaacaa cttatagatg gaacgagaat acatggtatt atactagaag caggaactgc
    37321 tgcaaatgta atacctgata tgggaaaagt aagattagag ataagagcaa aagaacaaaa
    37381 ttactttgat gaagtagtag aaaaagtgaa aaattgtgct agaggtgctg caatagctac
    37441 tggatgtgaa cttgaatttt atcactttga accaacttgt caaggattaa atgaaaataa
    37501 agttttagta gagatattta caaaagtcat ggaggaattt ggaatatatg aagatgaaca
    37561 agtattgcta ggttcaacag acatgggaaa tttaagtcaa ataatgccat gtatacatcc
    37621 tttgatgaaa ttttctgaaa atggagaaga attgcatacg aaagaatttt tagaagcttc
    37681 cataaatcca tatgcaaaag atagagtaat tgatggtata aaaatattgg ctttgacagg
    37741 atttaattta tttgaaaatt cagagttatt gaaaaaaatg aaagaggagt agactttaaa
    37801 caaaggggac ttgactatga ctaataaaac tgaaggtaaa aagaaaaaat taacattccc
    37861 agatgcatat gttttgatga taggtcttat tgtatttgca gcgataatga cttatattgt
    37921 tccctctgga acatatagta gaattgaaga tttaaatact ggaaatatgc ttgttcaagc
    37981 tggaagcttt aaatatggag agcaacatcc agttagcata atggatgtat ttagagctat
    38041 accaagtgga cttggaaaaa attctgtaac aattttcttt gtacttatta ttggaggagc
    38101 atttggtata gtaaatttta ctggttcact agatgtttta attggcagag ttatatctaa
    38161 aagtcaaggc agtaaaaaag gtgagattat aattacaagt ttagtattaa cttttggctt
    38221 agctggtgga gttgtaggta tgtatgaaga atgtattgct tttttaccaa tattaatgac
    38281 tctgtgcatt gctttaggat atgatgcttt agttgcagct ggtattttat tgttaggact
    38341 tgcatcaggt tatggttcag ctactattaa tccatttaca gtagggctag cacaaggtat
    38401 ttctgggtta ccactttttt caggcatgtg gtttagatgg atattttgga tttgtactat
    38461 gattttactt tcaggataca taatttttta ttgtaaaaag ataaaaaaag acccgagcaa
    38521 aagcttagtt tcagatattg attatagtca ttggcaatta gatgagtctt ctataaaaga
    38581 aaaattatca tctggtaaca tcagagtatt agttacattc tttggtggga tacttgtttt
    38641 gatgataatt attgtaaaat tttctttagg tatgtcagat ttatcagctt acttctttgc
    38701 tttaggaatt ttatgtgggg tagtttatgg aatgagtcca aataaaattg cttctgcatt
    38761 tgtaaaaggt atgcaagaga tggtttatcc agccattctg atagggtttg catctagcat
    38821 agtagtaata ctagaacaag gagtaatttt ggattcaata gtacatggat tatcattagt
    38881 tttaaattat gttcctagaa ttttcagtgg tggagtaatg atgattatgc aatccataat
    38941 taatttattt ataccttcag gcactggtca agctatggta accatgccac ttatggctcc
    39001 acttgcagat gttataggtg taccaagaca agttgcagtt ttagcttatc aaatggggga
    39061 tggttttgca aatggaatag ttccaacact tggagttctt atggctggta tatctattgc
    39121 tcatatacct tacacaagat ggtttaaatt tgcatctaag ataatactta tggagttggt
    39181 tttagggttt atatttttaa tgatttcagt acagattaat ttaggtcctt tttaatgtat
    39241 ttacgtaata tgtttataga attttaaggt aaattatatt gaggttaaat attttgaatt
    39301 ataatatgtt aggtttaatt atggtttttg aaataaaggg tgaactttgt gaagttcact
    39361 cttttaattt gtagcacaaa atatcattaa tgattacagc tttggtgata aaattaattt
    39421 caagatattt ataggagggg agtaatatgg agactttaaa aataagaaat attgaattga
    39481 gtggtacaaa ttatgagata ggatatgaat taggtaaatt aattgccaat actccaaaga
    39541 tactagaagg acaaattaat aaatctaatg tagtaacaaa ggaagaagag aaagagatgt
    39601 tagagttatt tgataaatat tgtccaggtc ttaacgaaga actgaaaggt tttgctgatg
    39661 cagttcaagt gaattgtaat caaattttgt attatactat gacctatctt aaacccggtt
    39721 gcagtcaagt tgcgttagca ccagaattaa ctacaaatgg gcatgtacta tttgcacgta
    39781 atttcgattt ttcacacaat atggaggact ttgttttatg taaaacgaaa gtaaaaggaa
    39841 aatatgcaca tataggcact actgttatgc aatttggaag aggggaagga atgaatgaat
    39901 gtggattagg cgtgagtcag tcatcatgtg gtattcctgt aggtaattca gttggtttaa
    39961 gaaaaccagc cgttgtagga ttacagtttt gggctgttat tagatattta ttagagaatt
    40021 gcaaagatgt agatgaggcg ttagaatata tagaagatat gccaattgca tataatataa
    40081 atttgttact tgcagataag tctggaaata ttgcacttgt agagacttta gatggaaaaa
    40141 aaggagtaaa tagaattaat agactagaaa agcagaggga acatttttta cactctacta
    40201 accatattca tattgatgaa cttcataaat tagaaccaca atcaattaaa aattctattc
    40261 atagatataa attaattaaa gaatatataa acaattctaa aaaagttgga gagaaagagt
    40321 taatgaattt gttgtcctca aagtatccaa atggtttatc ttgtaattac tataatgatt
    40381 tttttggtac tttaaaaagt atagttatgg atttaaatac tggtaaattt aatattttat
    40441 ggggtggatt agagagtaat aactgggaga gttactattt aaaagacgac gttaaagcta
    40501 caacacatct gataaatata aacattgaaa aggcaccatc tgactttttc gatttcgttg
    40561 aataaaaatg tgtttaatta gtttaaataa ttatgctcta taaatcagtt aaaagttttt
    40621 atttgtctta ttgaattggt tataatattt tagtatagtt aaaaatagtg ttactttaaa
    40681 tatttaaaga ttttaaatag aagagaggtg ccatattgga ttacttagag tattttgaaa
    40741 aagctgtaat ttatattgaa aataatttac aagaaaatat aactgtaaat gatgtggcaa
    40801 aagagtctgg atattcttat tatcatttaa cacgcttatt taagtctatg tttggtgaga
    40861 gtgtaggaag ctacataaaa aaaagacgat tagtaaatag cacaaaagaa cttttataca
    40921 gtgataaaaa agtgatagat atagctattg gtagcgggtt tgaatcttca gaagcattta
    40981 gtagagcttt taaatctata tacaaagtta gccctataga gtatagaaaa aatagaattg
    41041 atgtatttgt tggtaacaag aagaaattag aattagactt tatgagacat cttatcggaa
    41101 atataacgat taaaccagtt ataaaagaaa tagatgaaat aaagataata ggtataaaag
    41161 ataaagtgat actagaaaat aattcattac ctgaactatg ggataagttt agaaaggtac
    41221 accaaattgt tccaaatact ttaccatcag agagagtttt tggaatctgt gaagcaacat
    41281 ctgaaataca cctaattagt gaaagtatgg agtttaatga aataataggg gttgaagtta
    41341 gtagttatga atcgattcca aattcatttg tttcaaaaac tattacagaa ggaaagtatg
    41401 ctgtatttac tcatactggt agcttagaga atttagataa aacctatgaa tatatatggg
    41461 gtacttggtt tttaaactca aaagaagagt ttgatacaag agatgatttt gaagtttatg
    41521 atgaacgatt tttaggtcct aataatataa attcacaaat tgatatttat atacctataa
    41581 aataatctat aagaaactaa aaaataattt gattaaaaaa tagatgcttg aaatagcatc
    41641 tattttttta tttttatcaa gtttaaataa ttttaacaat aaaagaaata gaaagaagtt
    41701 cttaaatttc taataagaat ttagaatata gtcgaaataa aaattatata tttctgaaaa
    41761 ttctaattag tacaattttt tccgttgtaa aattgaaaaa agatgtattt atttatcaaa
    41821 aatattatat taaaatgata ttaataaaaa aaacatttat aataatagcg tatagtaaag
    41881 aaaaaagaat taatttgtaa aatttatggt gagtagtaaa attaaaaatt taaaaacgtt
    41941 atagggaggt tataatttta tggaaaacgt tattacaggt ctaagtaaag gtgcagagtg
    42001 gtttataggt ttgtttcaga aagggggaga acaatttata ggtcttgttt cagggactct
    42061 tccaacacta attgtattaa tggtagctat taactctttg attaagataa ttggtgaaga
    42121 aagagtcaat aattgggctt ctaagctagg aaaaaattct tttacaagat atattttact
    42181 tccgctagta tcagtatttt tcttgggaaa tcctatgtgt tatacatttg gtagattttt
    42241 aaaagaagaa cacaaagcag gtttttatga tgcagcagtt tcatttgtac atccaattac
    42301 agggcttttt ccacatgcaa atgcaggaga actttttgta tggttaggaa tatcagcggg
    42361 tttgactact ttaggtaaag aaactactac actggcatta tggtatttta tagttggtct
    42421 aattgtaatt tttataagag gtatagtaac agaaaaaatg tatgcttttt taacaagaaa
    42481 aaataaagta gcagataagg cttaggaggt agataaaatg gatgaaaata aaatattaaa
    42541 aatagaaaaa ggaacttcag gttggggagg tcctttatat ataaaaaaag aaggcaatag
    42601 aaataagata ttatcaatga ctgctggtgg tatccatgaa gtaacattaa aaataaaaga
    42661 actactgggt tgtgaagttg tagatggatt taaaactgga gtttctgatg aagaagtggc
    42721 agtggttatt attgattgtg gtggaactgc tagatgtgga gtttatccaa agaaaaaaat
    42781 accgacaatc aatgtaaatc cagttggaaa aacaggtcct ttagcaaaat ttataacaga
    42841 ggagtattat gtatcagatg ttagtcctaa ctgtataagt gttgtaaatg gagaagatat
    42901 gcaaaaaaaa tctcaagaaa ataaaagtga aaataagagt tctattagaa agcctgataa
    42961 ttatgatgag gttaagtcaa aagcacaagg agaatatgct aaaaagaata taatactttc
    43021 tattggtcaa ggagcaggac aagtagtatc aaaattttat gatgcaggtc gagatactat
    43081 tcaaatggta atgaataatg taataccatt tatggcattt gtaagcatgc ttatgggaat
    43141 tattttagca tctggattgg gagattggat tgcaaaagtc atatctccac ttgcaggtaa
    43201 tatcggtgga ttattgatta tatcaataat ttgtacactt ccattcttat caccaatatt
    43261 agggcctgga gcagttatag cacaagtggt aggaactctt gtaggtacac agattggtct
    43321 tggagcaata ccagcatatt tagcgcttcc agctttattt gcaataaatg gtcaagctgg
    43381 atgtgatttt gtcccagtag gattgagttt aggagaagca gaaccagaaa ctgtagagta
    43441 tggtgttcca gccctatttt actctcgttt aataactgga ccaatatctg ttattattgc
    43501 atatggagtt gcagtatttg cattgagata atatttaatg tcaatataag gcttggaatt
    43561 aattactaaa attgtaaata taaatttaag ctagtcaaga ttttttgtta atgaaagact
    43621 agcttttata ctattaatta gctgtaatta tcgagttaga ttaatactaa attttccttt
    43681 attaaagtga aattttatgt attaatttgg tttcaagttt gtactagaat gaaatcaagg
    43741 aggagataca aaatgagtgt aactgagaaa attccttcta ttgaccacaa gatatttaag
    43801 atattgatta tgtgcagtaa aaaagagttt gtgagtatta attcaatagc aaatgaattg
    43861 aatgtcacaa ctagaagtgt aaggacgtat ataaaacaat tgaataaaga tttaggtaat
    43921 gatatagcaa taattaaata tataaagggt caaggctata aactggaaat aaaagatgag
    43981 cagatactca ataagattat tgatataaat agaaaaaatg tattttcatt aaattcaaaa
    44041 gaagatagag tagagtttat actaaattac ttgacagaac tagatggatt tattacactt
    44101 gatagtttag ctgatgagat gtgtgtagga agaactactt tagtaaatga ttttcagtat
    44161 gtagaaaaag ttttggcttc atataattta aacttaatta aaaaacagaa tacaggtatg
    44221 aaattaaatg gaaatgaact tgatattaga ctgtttatat taaatcagtt gtataaaaat
    44281 tcaaggaagg atttcaataa ctcaaagtat tttaaaggaa tcaaaaaaga agaaatcata
    44341 aatttagaag aaaaactatt gactttattt aaaaaaaata acttttatgt tacagatgaa
    44401 atgttaagag aggttattaa ctatatagta gttttagtct atagagtaaa agaaacgaag
    44461 aaagtaaagg actatgatgt aaagtttgat ttactcaaat cgtatgatga gtactttatt
    44521 gctagggaaa taaaacatat aatatcagaa atgtttgaat gtattttaaa tgatgaagaa
    44581 attatttatt taaccatacc actagtgagt ggaaatgcac cagcatcaga atgtgcttta
    44641 aatagtagta gaattaataa aaatattgat gagttgatgg aaagtatatt taatcaaata
    44701 tatgttgata tgggtatttt tataaatgag gatgaattaa gagtaggatt gggatatcat
    44761 cttagtttta ctttgaacag gctattattt aatataaagt taaaaaatgt tttgctagaa
    44821 gagattaagc aaaactatat acttccattt aaattagcac aaatagcagg taaagtaata
    44881 gaaaaaaaat ataatttaga agtttcagaa gatgagattg ggtatatagc aattcatttc
    44941 agtggatatt tagaaagaaa tagtagtaga ttctattcaa taaagaaaat agcaattata
    45001 tgtagtacag gtctaggaac agcaaaacta ttaaaaataa gggtagaaaa actgatagga
    45061 aataatccta aaattgacac tctttcaagc tttaatttga gaaatattaa tttagatgaa
    45121 tacgatatag tttttacaac gattgattta gacacatcta atataaatac aatagtatta
    45181 aaaataaata caatatttga tgaaaataaa ctaagagaac aattaaaaac agtactatgc
    45241 ctaagagaag gaaatattga tactactaac tctacaaatt tactaataaa taatttgtta
    45301 gatgaagata aatttatgat attaaatgaa aagactatac ttgattcatt agaaaaaatg
    45361 atggataatc ttatggattt gggatgtatt gatgataagt ttagaaaaaa tatattcaat
    45421 agagaagaaa aatctcctac agtatttgat aaaggtttat tatttccaca ttctgtgaat
    45481 gaaaaatcag ataaattttt aatggcagtt ggaattttag aagagccaat aaaatatgca
    45541 aatagaaaca taaaaataat tcttatgaca atgtttccat gtgaaaataa gatggattca
    45601 gacttattgg taaaaattta tgaagaaatt ttaaagatag ggcaagatgt aaaattgaca
    45661 aataaaataa gtaagtgtag aagtttttta gaatttaaaa aggtattact taaaaacctt
    45721 atgtaactac tgtacagaat ctatagttat tgtacagatt aaaagaataa tgtgattttt
    45781 ggaaggtgta taaatatgaa agtactagtg attttatttg ctgcttatat tttgaatacc
    45841 atacttataa tgaagcagaa taagttgtat tttaaaactt taaatagagc taaaaaaaag
    45901 ggtgatatag tgtccacagg caaaaagaaa agctattttt ctaaaggaag tatagccatt
    45961 atatcttcag attcaaatgg atttataaag tttggagaga ttttaaaagg tcgtacagta
    46021 atggctaagt ttaaagagat tgaagacata gaaggattag atatatatag tgcagagcaa
    46081 aaatttaaaa atgaagaaag tattgtacaa gctataaaat ttataaaaga aaaaataaat
    46141 gtttctttta attaactcaa tataaatata aattatcagg aggaatgtca tgaaatatga
    46201 agttaagata agtggaatag gaagtttagt taaagagtta atggatgaaa gtaattgtct
    46261 tattatatat gatgaaacca ttaatgatga cgacttaaag gatatatctg taattcattc
    46321 gatatcgaca ttaagaagtg atgttgaaat aggggataca cttactatag gaaatagaga
    46381 ttattgtata gtttcagttg gtgatattgc tcaaaagact cttagagaaa ttgggcattg
    46441 tacaatcaaa tttgatggaa aaaatgaagt aaatttacca ggagaaattc atgtggaaat
    46501 aggaaatcca gatataacta ttggagattt aataactatt tcttaatttg aaaataaaat
    46561 tattataaca ggaggaattg gtatgttaga tttaaacaga aaacttgcaa aattggaaga
    46621 ggaaggtaaa aagataagag tagctcttat aggggctggg catatgggaa atggaatggt
    46681 aagccaaatg gcaaatatga aaggtattga agcttctatt gttgtagata taaatttgga
    46741 gttggctcat aaagctttta ctgatgcagg aatagatgaa gaaattatag acaatgtaac
    46801 aaatgaaaat gatgcagaaa taaaattaca agaaggaaaa gtattgacat gtaatgattt
    46861 tcttgtagct tgtaaaacta agtcaataga tgtagttata gatgcaactg ggggtatcgc
    46921 aattggtgca gagatagcat taaactctat tttaaataaa aaacatatag ttatgttaaa
    46981 tgctgaaact gattgtgttg ttggaccaat acttaaaaaa ttggcagatg atgctggagt
    47041 aatatttaca ggttctgcag gagatgagcc aggtgcagta atggagttat ttgattttgc
    47101 agatgcaatg ggatttgaag ttagagtgat aggtaaaggt aaaaataata aattagattt
    47161 agattgtaac cctgatacag ttagagaaga agcagaaata aaaggagctt cacctcatat
    47221 gatagcttct tttaaagaag gaactaaaac aatggtagaa atggctttaa tgtgtaatgc
    47281 aactggattt gtacctgatg taagaggcgg ccatggcatt gaagctactg ttaatgaagt
    47341 acctaagaaa tacgcattaa aaagcgaagg tggagtatta gataactatg gtgtagttga
    47401 ttttgtaaat ggtatagcac ctggagtttt cgtagtagta gcccataaat taaaagcagt
    47461 taatgatgaa ttaaaatatt taagtatggg tgatggacct aattacatat tatatagacc
    47521 atatcattta tgtagcttag agactccttt atcagcagct atggcagttt tagaacataa
    47581 agctacaata gttcctaaag ctggattagt tgcagaagtt atgactatag ctaagaaaga
    47641 tttgaaaaaa ggtgagtata tggatggcta tggagcatat acatgctatg gcactataga
    47701 aaaatacgat gtagcaaagg ctatgaaagc tgtacctatt ggtttgataa gtaaaaagac
    47761 taaagttgtc aaagatatta aaaaaggtga agttataact tacgatatgg tagagataga
    47821 aaaagatact actctatatc atttaagaca attacaagaa aaaatatttg ggtaagattt
    47881 gatagtaata taaatggata ttaacaaaaa gggttgatga ttatttttaa atcaaccctt
    47941 ttaaattttt gtatattctt gttaggatac tttctttaga attatattat aggttatttg
    48001 tagttataaa aattattttt aattagttct gcaattttat attcatatta aaataatatt
    48061 attaaaaatt ttaat
//
LOCUS       DAMKOJ010000024        47421 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000024 DAMKOJ010000000
VERSION     DAMKOJ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47421
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.025"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(81..485)
                     /locus_tag="PC592_001469"
     CDS             complement(81..485)
                     /locus_tag="PC592_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF4055458.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNYVKPWKDAEIYIDKYMVK
                     QDISKDNVKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLKSNEELKSVKYPPIYLKYKPDK"
     gene            complement(677..1864)
                     /locus_tag="PC592_001470"
     CDS             complement(677..1864)
                     /locus_tag="PC592_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDF4055459.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVHRGNEVLYYSFNEFRDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPRLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQSFIEIIRIIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIESLGSIPNNF
                     KVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVANRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(1896..2321)
                     /locus_tag="PC592_001471"
     CDS             complement(1896..2321)
                     /locus_tag="PC592_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055460.1"
                     /translation="MINENLKSLRKIHQYTQEELAEKLNVSRQSIAKWESGESIPDIG
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVPKEE"
     gene            complement(2759..4708)
                     /locus_tag="PC592_001472"
     CDS             complement(2759..4708)
                     /locus_tag="PC592_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF4055461.1"
                     /translation="MKRKYPNLCKPIKIGNVTFKNRMFSAPMGGTDITADCTIGSKST
                     AFYELRAKGGAGAVTISECMVHPETDGSHAYHLDLKIVDSLASFTYTADAIRRHGAIP
                     SVELSHSGQYSGTYLVDKDKKRGLSQWGVSPSVRPDGLEIKELTEEIIAEIVESYGNV
                     AALAKRAGFEMIMVHGGHGWLINQFLSPYFNKRNDKYGGSLENRVRFAKEVLDSVRKA
                     VGPGFPIEFRMSGSELFEGGYDLDYGVEIAKLLESRVDLLHVSAGTYQRGFAVTHPSM
                     FLEHGCNVYLAEEIKKHVNIPVATIGALNDPEMMEEIIASGKADVIYMARALLADHEL
                     PRKVMSNQDEKIVKCLRCFTCMAERATTSTRRCTVNPLIGRELDGTEVIPVLKPKKVL
                     IAGGGPGGLQTAITAAKRGHKVILCEKTNELGGILKGEQALPFKYEMYELGNTFGKIA
                     EDLGVEVRLNTRVTKEYVENENVDALIIAVGSEPLVPSIEGLDGENVVIVNDYYLEKE
                     KVTDEVVVLGGGLAGCEAAIHLAQEGKTVHLVEMRAELAPDANIRNRPILLQEIEKQG
                     IYVYTEHKGLSVTTEGVVCMNKSGNKINIPGTSVICALGQKPRREVVDALLDCAPYVA
                     QIGDCVRASTITNAVYQGHHVALDI"
     gene            complement(4680..5978)
                     /locus_tag="PC592_001473"
     CDS             complement(4680..5978)
                     /locus_tag="PC592_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HDF4055462.1"
                     /translation="MNLTQKRWIILIASCFINLCIGSIYAWSVFASPMAEHLNSIAGT
                     TFTAASLAIVFTVTNSVGPITMITGGMINDKFGPKKVVFVGGLVFGIGMILAGFSKGL
                     PMLILSYGIITGLGVGMVYGCTISNSIKFFPDKSGLVGGITTAAYGFSSVIMPPVANW
                     IINKYGVTSAFKSIGLVFLIIVCVSSFFIKKCPADFTPEGWIPPEKKGKVRVIINKNW
                     KEMLSTPIFYLMIIILTCGAFYGLMCVSLASSLATNMIGMTSSDAAIVVSILALFNTL
                     GRIVAGYISDKIGRINTLAGALVISIFGLLCLLFSREGDVATFYIGIIIIGICFGSFM
                     GIFPGFTVDKFGPKNNSVNYGIMFIGFAFAGYVGPAVMKNVYATDGNYQRAFIIAIVI
                     ALIGFILTFLYKYINKIQNLKIENLMKGDIKDEKKISKSM"
     gene            6229..6786
                     /locus_tag="PC592_001474"
     CDS             6229..6786
                     /locus_tag="PC592_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF4055463.1"
                     /translation="MRTLKYAILGLLNRNPMTGYDIVKEFNFQLAEFWNAKHSQIYPE
                     LKKLVNEKLIVYDIKISGDVLEKKLYTITEKGKDEFLKWLEKDEPMERTPKDIFRLRM
                     YFSNNLDIDTRLILLEHQLLQHQERIAFLYSQMERYSEVPPLNSNDFGDYIVLDGAII
                     REQGAIKWLTNCINHHKNLDNTTLK"
     gene            7210..7959
                     /locus_tag="PC592_001475"
     CDS             7210..7959
                     /locus_tag="PC592_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF4055464.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKKTKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGAIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(8119..8484)
                     /locus_tag="PC592_001476"
     CDS             complement(8119..8484)
                     /locus_tag="PC592_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF4055465.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILITLLESDFN
                     GIRVGEITEKTHLSRPAVSHHLKILKEAEIVNVRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(8500..9276)
                     /locus_tag="PC592_001477"
     CDS             complement(8500..9276)
                     /locus_tag="PC592_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4055466.1"
                     /translation="MKYQHIIKVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPQKAITLTGFDEPPIELTNKPNLDSDELLMAIKSRRSIRKFKDKEVSLE
                     IVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDKFFFKNAPIAIMIITKDKISGSLAASNMSLMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEAANVRYL"
     gene            complement(9695..11122)
                     /gene="ascB"
                     /locus_tag="PC592_001478"
     CDS             complement(9695..11122)
                     /gene="ascB"
                     /locus_tag="PC592_001478"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF4055467.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDKHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPRGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEIDSNNLVGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGIAPEMESGDIELLNKYTVDFISFSYYNSRCVRTDENAGDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVYIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRTKKKSFEWYKKVIASNGEDLY"
     gene            complement(11183..13111)
                     /locus_tag="PC592_001479"
     CDS             complement(11183..13111)
                     /locus_tag="PC592_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4055468.1"
                     /translation="MGKYKQLAQEIVKNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDNSSANSETKKSGSILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKFIPDLVKFFFVPMLTLLITVPVALIV
                     LGPIATFGSTVISQVVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVASPIKGEVLKLS
                     EIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDAGVEVLIHIG
                     LNTIQLEGRCFEACIKQGDRITKGQTILNFDIDAIKELGYSVVTPIVITNSSQFLDVV
                     ETGRKNIELEDNLITVLF"
     gene            complement(13256..14098)
                     /locus_tag="PC592_001480"
     CDS             complement(13256..14098)
                     /locus_tag="PC592_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4055469.1"
                     /translation="MIINKILNNNVVITLDDNDEEIIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEVSNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGVKLPEDEAGFIAFHI
                     VNAQLSEGHTFASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLN
                     NAHEGGTDKELLSIIKSKYNKEFECVVKIKDFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNI"
     gene            complement(14270..14416)
                     /locus_tag="PC592_001481"
                     /pseudo
     CDS             complement(14270..14416)
                     /locus_tag="PC592_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893832.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            complement(14516..14965)
                     /locus_tag="PC592_001482"
     CDS             complement(14516..14965)
                     /locus_tag="PC592_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055470.1"
                     /translation="MEIREILSEESIILDLKSTTKEGIIQELVDKLYDTGSIDLKSKF
                     IKALKRREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGIDWPSIDGLPVKVIIM
                     FAMPQSGDNEDMTLISKIAYILGGKDISERLLNANTKKEILDIFYEV"
     gene            complement(14955..16862)
                     /locus_tag="PC592_001483"
     CDS             complement(14955..16862)
                     /locus_tag="PC592_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4055471.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKIIE
                     KYLETFNIKIDIKRGYGILIESLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISKLTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTISQPYYINLITHILICLKRIEEGNQIESQEEREVSVDNLDELVYQNVTALIGKIEN
                     RYGVKITKDEIMYIYIFLVSSGFSSESNNSYNDESYRLSESEKFSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSNRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDISNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVMQMESLIGVDLGSKYKSISLGKDLNIYIHNQSKLN
                     KGIMNVNNINRTIDIYLETSNQSFLKNILMEISNLYRQKSYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(17129..19024)
                     /locus_tag="PC592_001484"
     CDS             complement(17129..19024)
                     /locus_tag="PC592_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055472.1"
                     /translation="MIGQILRSDCIVLDKQLQTKKDVIDYMANHLYHGNYINDKEKFI
                     VDINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDKEITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMDENLLKHLLSAETPYEILSIFNNKAVESGDSSDNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQMSRFIGKKVLQKKVADAKNVSLAKNLIINAENGMAKEIKPGGRTLEDSK
                     EILQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFSTG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSSPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVEVLGA"
     gene            complement(19060..19938)
                     /locus_tag="PC592_001485"
     CDS             complement(19060..19938)
                     /locus_tag="PC592_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDF4055473.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREVVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FIEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCREVLEKNSSLYEPDTIYPPCIDAAREVIEFKMN
                     LFNTIDKLKCFYKNKN"
     gene            complement(20490..22184)
                     /locus_tag="PC592_001486"
     CDS             complement(20490..22184)
                     /locus_tag="PC592_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF4055474.1"
                     /translation="MIKKIKRSKFTPKNVISIILYSILFWILIGYIIIPIGNTFTQAF
                     QGKGGYSFEVFKEYFSNTNNLKVVSNTIILGFGSVLVCGIMGISLALYMTFVCDKHKK
                     IIHILLLSPMMIPGVIMVIACIQLYGESGIVTKSIEILLSFIKKPYDFSGLKGVLFVV
                     AYTQYVYFYLNVYVALKYVDYSTVEAAKGMGASKIRVFFDVIWPVITPAIITSTIITF
                     ASGISSFSAPNLIGGGFKVLSTQIVRSKANNHMDIASVQVIILLLMGISFMILLQYYG
                     KKYGVVASLKSQGYKVHNRKKDLFTFVCKVIIEIQIVMIMLPIVTIVYLSFVSTHSIM
                     TTIFPRDFTLENYQMIFQKSRVLQPILNSLKMSLMAVVIGLIITIPVSYLVIKKDTTY
                     NRLAKFIIMLPWSMPASAIAVNLINTFNQKSIFAFNESLIGGFYIVPIAYTIYALPLL
                     FSSNEVAMKSINLGLEESSRSLGAGRIKTFYNVIVPNMMPGIISGAILVFIRTIGEYT
                     MSALLYGVYNRPISISIVTNMQEFKIGVSMAYGVLVIGICYIALGIIFKLDRKRFT"
     gene            complement(22186..23178)
                     /locus_tag="PC592_001487"
     CDS             complement(22186..23178)
                     /locus_tag="PC592_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055475.1"
                     /translation="MKNIELKEINHYYGKEKVLYDINISIKEGEFFTLLGPSGCGKTT
                     ILRIIGGFIKPSSGSIYVGDKNITNLEPENRNMGTVFQNYALFPNMTVEENVSYGLKI
                     KKLSKKIIKEKCDNYLELAGMKDFRKKKIDELSGGQQQRVAVARSLATEPTMLLLDEP
                     MSNLDIALRIKMREEIREIQQKIGITTLFITHDQQEALAISDRIAVMDKGKVLQIGVP
                     MEVYKKPLNDFVANFVGTSNCIEKEDYVNFNIEKETKPYIYKRPEEMVLLQNTNQSGF
                     IKVKVESKNFLGAILEYTVSNNGKKYQVTELNRLNNSNKLNVGDMAYLGVLQGN"
     gene            complement(23197..24054)
                     /locus_tag="PC592_001488"
     CDS             complement(23197..24054)
                     /locus_tag="PC592_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055476.1"
                     /translation="MGLKISDYKLLCNKGNGDFNEDIVGLSPYGAWVLDGATGLNNKN
                     LVSTESDAKWYVSWWNSYLHENMEREDSLKVIIKEGIEEITKEYYKLTYDKEVEAIDI
                     PSCSCSILKFYKDKIEYLLLGDCTLLVNHNESVKILKDETLCRLDKKIFDFMQEAKDV
                     TNLTLKERKAEVMPIIIENRLKKNTVGGYWALEFSKEAVDNCISGFIDIEYKMKIMMA
                     SDGFSCGYDRYKIFDKNEMMKIAEIKGIDYIYRKVRELEKDDEMAIEFPRFKIYDDSS
                     CVYLEIYKY"
     gene            complement(24332..25375)
                     /locus_tag="PC592_001489"
     CDS             complement(24332..25375)
                     /locus_tag="PC592_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF4055477.1"
                     /translation="MKRKIAVVLLTVAMLLSLVACSNDNTSKSDKLEDTLVVYTTHGE
                     DMLGAISEEFTKETGVNVEFINLKGELADRVRSEKDNPQADIMFGGDTSTYMQLKEEG
                     LYEKTKPSWNNELDKSYKDSDGYWYGTIKTPVMIFYNTKLLSADKVPKDWSDLTKEEY
                     KDLIVTRDSLSSSMRSTISNLINYYSNTKSEEEAWKYLEDLNKNIKNYYNSGSVMYSA
                     IGKGEAAISVAVLSDIIENKEKNNMPLEVVDAESGSVVITDCVAALKNAPHPNAAAKF
                     VDFVGSAKVQAMVANDFNRIPTLDSALKDSPKWMSKEYKAMDVDWSVIGKNQSNWIEK
                     WETDIIDNNKTIK"
     gene            complement(26341..27774)
                     /locus_tag="PC592_001490"
     CDS             complement(26341..27774)
                     /locus_tag="PC592_001490"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF4055478.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KVTDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPNGDESIPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     SRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAIPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITDEDKKILKEGTVDFIGCSYYLTTVVSADKTMKTTGNDSAGKA
                     DVVENPYLKTSDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     GYRIEYLASHIREMKKAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
     gene            complement(27797..29638)
                     /locus_tag="PC592_001491"
     CDS             complement(27797..29638)
                     /locus_tag="PC592_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4055479.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETITKKAVLQVQNTGEQGEKVSIVSRIFE
                     SISGAFSPLIPALAGAGMIKALLTILTIMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLGANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDVISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     DGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYITHMNAGDKVKKGDKIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            complement(29764..30597)
                     /locus_tag="PC592_001492"
     CDS             complement(29764..30597)
                     /locus_tag="PC592_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4055480.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGRDELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYKFSKKAVEYLRKKLDKDIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENANVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            complement(31163..31408)
                     /locus_tag="PC592_001493"
                     /pseudo
     CDS             complement(31163..31408)
                     /locus_tag="PC592_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(31635..31847)
                     /locus_tag="PC592_001494"
     CDS             complement(31635..31847)
                     /locus_tag="PC592_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055481.1"
                     /translation="MAILMKTKIKEYREKFLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEQE"
     gene            complement(31848..32264)
                     /locus_tag="PC592_001495"
     CDS             complement(31848..32264)
                     /locus_tag="PC592_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055482.1"
                     /translation="MSKSETGVKSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNIDTGIILIAVLYIQSLSKLVLYIYFDKRGICN"
     gene            complement(33572..34201)
                     /locus_tag="PC592_001496"
     CDS             complement(33572..34201)
                     /locus_tag="PC592_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDF4055483.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKAKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVVPNYSGEKYYKMESVVSDEHLV
                     TAPGIAPLEFTFQVLKLLEVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(34280..35242)
                     /locus_tag="PC592_001497"
     CDS             complement(34280..35242)
                     /locus_tag="PC592_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF4055484.1"
                     /translation="MAKIDNMMSILWMLSSDKKITAKEIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDIGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLIALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEIRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQSIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIQPLSLRKKMIEDLLELIDYYQI"
     gene            complement(35614..36052)
                     /locus_tag="PC592_001498"
                     /pseudo
     CDS             complement(35614..36052)
                     /locus_tag="PC592_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427593.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
     gene            complement(36967..40443)
                     /locus_tag="PC592_001499"
     CDS             complement(36967..40443)
                     /locus_tag="PC592_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055485.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNVSNTFADTIEESTNAGN
                     VEGDTNAGNVEGDTNAGNAEGDTNAGNAEGDTNAGNAEGDTNAGNAEGDTNAGNAEGD
                     TNVGNAEGDTNVGNAEGDTNAGNAEGDTNEGNAEGDTNEVLVEEDTNAEEYDSVGDFK
                     ISGGEINVDFKFESGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFNGVNIK
                     TASNSPFTLTPDKDGGAYAHIILQDGSKNILKSGDQLYPGIRAGKSTTLIIDDSVVNR
                     DIEGEFIVPENGKIPRDVTLENGDKLKKGDRLTLLDSKNRGSLTAVGNSYAAGIGGGD
                     TENGGNIIINGGIINATAMEGYNTGFGAGIGGGSIGDGGDITINGGTVTAKGAYHGAG
                     IGGAYYISGNHTLSPSVVDRNKGGGYSGNITINGGLCYSYGGAHGSAFGDGCVNPGAN
                     RGYRVLVTGGTVLPYMTGAGDWIFDLSAITGDVIVTGGSLKATTFKSSGETVAYGDLE
                     KKTKVFMSKVSLKYLGQDKVNTKLVDDFTMQINGKEYPYGAPSYTDDQGVLYLWFSDK
                     FTGSEVSVKLAIVDKDTGDTLKSDTFYIKDIGPTTPFLKQYEEFIIDEINTPPGSINK
                     RYDGLPFGKEQEKAFLDWILKDGIPVTNPKGGKLTDGTYIIISSQRLNEETMEPDTSL
                     GSDDLTKQVDVGKYQLIITSKQYASVAPFNESYWGHRSHYNYAEITPADTETSLVVET
                     PKVKTDVFKPTDTFTLNATVSPDKKEGPDCASPKGYVQFYINGKEYKDPVELKTHDKV
                     SESHNYSTASIEWKPLDSNHHILNTEQTITVKYIGDDINYTKDSKDEKKLKLDITNVD
                     IDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNRDGIWKP
                     DKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTDSGGYDTGNPDPNKPDPD
                     NPNPDNGGNSKPDSGNGGNSKPDSDNGGNSKPDIDTDGDGKPDIDGDGKPDIDIDTDG
                     DGKPDINIDTDGDGKPDINIDIDGDGKPDINIDIDGDGKPDINIDIDGDGKPDINIDI
                     DGDGKSDVNIDIDGDGKPDINIDTDESLDSNAGQNVQTGDQSNIMLDLALMFTSLFFL
                     IKNLINKYLRRK"
     gene            40713..41247
                     /locus_tag="PC592_001500"
                     /pseudo
     CDS             40713..41247
                     /locus_tag="PC592_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
     gene            41446..42609
                     /locus_tag="PC592_001501"
                     /pseudo
     CDS             41446..42609
                     /locus_tag="PC592_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429590.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(42747..43346)
                     /locus_tag="PC592_001502"
     CDS             complement(42747..43346)
                     /locus_tag="PC592_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055486.1"
                     /translation="MSQNIDFNKSNFYLRLDERLAVPLKYAYVSTILKFQKWRGCTFD
                     FSNTKLEKLKNIIVHGDNDNYNKLLMVIKKRYDDILDEEFWHIEIKELPYIDRGFKSN
                     KDIITTFIHGKYYPKRKAFRHIDFIKNQYPFKEYCSKQEDNSTNEIKIDFYITKECHY
                     KVWCIENIDIQEHIWCELVNVSLSEEYRKLFGEILDSSK"
     gene            complement(43372..43671)
                     /locus_tag="PC592_001503"
     CDS             complement(43372..43671)
                     /locus_tag="PC592_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055487.1"
                     /translation="MAYSDIYSISCGEKEFPTNITIDEDLLFCVVTCFVLDRFRYDDL
                     NIKSVISYEKHMYDINDYKLTKIENLDFKQNGFIYDKKYYLYNIFIDKSPLNKYK"
     gene            complement(43699..43950)
                     /locus_tag="PC592_001504"
     CDS             complement(43699..43950)
                     /locus_tag="PC592_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HDF4055488.1"
                     /translation="MEKLIQDIKNLDSYYNTSYYTFHLDEPLWKSLKVRNWSGVPYYI
                     KQLCNEVKSLIKERNLTQSEIFQYITDPKKRTHYFFVAQ"
     gene            complement(44165..46096)
                     /locus_tag="PC592_001505"
     CDS             complement(44165..46096)
                     /locus_tag="PC592_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4055489.1"
                     /translation="MFLDRIIMENVGPIDNLDIGFPFNEDGSPKPIIFVGENGKGKST
                     VLSNIVDSLFEFAKQPYNDITETNKDGTTPYFKVLSWKNTKVGCDYSFSFINFVNGEQ
                     NFQYIEKLGNLSFEQCIEKTSGLLNLDNNWGNRKNIKDITKNKEYFEEEFANKSFCFF
                     PPNRYETPHWMNQNIISENLITINDKISGKLNKPIIVQNVTETNIKWLLDIIVDSRAD
                     LIQSDLGGWNSEQDLNNIRLLKIARENVEEILSEIVKKDVKFGLNWRNSGGSRFNIID
                     RSTNSMIIPTLDALSTGESALFNMFSTIIRYSDYGDINKSIKLNEIEGIVIIDEIDLH
                     LHSSIQCDVLPKLIKKFPKVQFIITSHSPLFILGMKDIFKEDGFKIYEMPTGENIGPE
                     EFSEFERSYEYYKRTELFSKDIQDILKSKNGKTLIITEGKTDWKHMKAGLLKLKEQGL
                     YHDLDIEFLEYENDIKMGYNNLINICEAASKLRNNNKVICVFDRDLSDRDLRKVKDEN
                     TNYKLWGNNVISMVLPLPDNRVEIDKIMCIEHYYSDEEIKTFYKGRRLFLGDEFNSKL
                     GLHILGDKICQDKNKCGKKSIIDSGCVVCDIKNPEDNIALSKNDFADSILNGVEEFKN
                     ISFENFKLVFDLIQILVNE"
     gene            complement(46171..46520)
                     /gene="ssrA"
                     /locus_tag="PC592_001506"
     tmRNA           complement(46171..46520)
                     /gene="ssrA"
                     /locus_tag="PC592_001506"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(46678..47133)
                     /gene="smpB"
                     /locus_tag="PC592_001507"
     CDS             complement(46678..47133)
                     /gene="smpB"
                     /locus_tag="PC592_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDF4055490.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
BASE COUNT        15610 a         8337 c         5000 g        18474 t
ORIGIN      
        1 tcttaaattt aattttattt aaacactcta gtgatatttt taaataaatt ttaataaaaa
       61 tccttctatt ttgtcataaa tcatttatct ggcttatatt taagatatat tggtggatac
      121 tttacacttt ttaattcctc attacttttt aaaagtttat tattattttc catatcataa
      181 atttgtaaca ttactttatt tacatataga gcataataat tatcactata aaaatattga
      241 tactcatatc gagggtcatc tttgtaatac actttgtata gtattccttc ataacttgcc
      301 ttcttggctt tttcttttgt aatacttttt acattatctt ttgaaatatc ttgctttacc
      361 atatacttat caatatatat ttcagcatct ttccatggtt taacatagtt tttatataca
      421 acaaaccctg ttacacttat aatacctata attaatacta taaaaataac tttatatttt
      481 ttcatattaa tcctccttca tttattgttt aaaacttaat ataatgcatt aaaaaaagga
      541 tgttatcttt tttattaaaa tataacatcc ctcatattta gcatcaatat atatgcccca
      601 actagtaggt taaaaggccc cactgtcagt actttgatta aattgcatgt atgtatatat
      661 atttttaaaa aatctattat atatcaactt gtctactatt acatataatc tgtaatatta
      721 catctgctgc tttttttgag cctcctgcat tataaaagct ttttgatagt ttagttgcat
      781 tttctttata ttcattgtca tttataactt gaaatactgc ttttttaata ctttctgact
      841 tatcctcttt taacataatt cctgctccca aatgaacaac tctattagct accattctct
      901 gctccgaatg ttgaggaaat aataccatgg gtactccata atataaactt tcattaacac
      961 tattcatccc agaatgagta acaaacacat cagttttttg aagtatagca atctgttcaa
     1021 cactattttt aaccttaaaa ttatttggta tacttcccaa actttcaata tcagtacttc
     1081 taccaacaga cataatcaca tcaacatcag aatctttaaa tgcatttata cagtttttat
     1141 aaaagctaac atttttatta ttaattgtac caagcgaaat atatattagc tttctttttc
     1201 tctctttagg ttcaataatc aactttgata ctgatggacc tacaaatgaa tacttactag
     1261 agaaggtttc taccattggt tgaaattctt ttgatgtata tacaatagta tccgtatcat
     1321 tatcattaga aactatagaa ataaaatttt ttacttcata cccttttctt tgtaaaagct
     1381 ttattttttt attaatacgt cttacaccaa aaattatacg tataatttct ataaagcttt
     1441 gtttcatcaa ctttgctgta tgtttattaa atgcaaaagt tgttgtagag catacatatg
     1501 gaatattaag tttttgtgca aataactttc cccaaaaact taatgaatct gatacaatgc
     1561 aatctggatt aaaatcttta agttctctac aaactttttc atctaaagaa atagtagtat
     1621 ctactatcat ctcaattaat ctgggaaaat ccttaccaat ttttttctca tctccaggaa
     1681 gtagttctgg aaggtattta tcacaacaaa taaattttgc tccagcacct tcaattttat
     1741 ctctaaattc attaaaagaa taatacaata cttcatttcc tctatgcact aactcacgaa
     1801 ctacttcaat agtaggatta gtatgaccat atgcaggaat gctaaaaaat actattttac
     1861 tcatatttca tacctccttt tataattttt taaaatcatt cttctttagg tactactccc
     1921 acatgaccta taaaatttat caaatcacgt tgatgaacaa ttcctaatcc tctttcctca
     1981 tctccaagta ccaataattt atctcctgca tttatattaa atacttctct tgcttctttt
     2041 ggaatgacaa tttgaccacg ttcaccaact actactgctc caaagaaaaa ctttccttta
     2101 ggaggtacta taatacctgt tttttcttcc gaatgattaa ctaagtcatc tagtttgaca
     2161 ttgtacaatt ttgcaagttt aatgcaacta cctatatcag gaatagattc tccactttcc
     2221 cattttgcta ttgattgtct agaaacatta agtttttcag ctaattcttc ttgtgtatac
     2281 tggtggattt ttcttagact ttttaaattc tcattaatca tatttttcat acctcctatg
     2341 tttataatat tggatttatt atttaaattc tattaactaa tcttaacatt catatatata
     2401 tttatatact ttttattaga taaatttatt gtttaggtaa catacttcct taagttataa
     2461 taaataaaag caagcacaaa tctatcaact tttgctaaag tatttaagtt agagtcattt
     2521 acattgttaa atacttctac accttaaaaa gttttactca tcaatcaaat gaaaacttgc
     2581 aataagaatt aaaattataa taacaaaggt gctgtctcaa aataaagata atcttttttc
     2641 attattgaaa tgataaaaat atatttgatt tcacgcaaaa aagtgtctca tgaactaaaa
     2701 agttcatttt gagacactcc ttttttataa taaaacaata ctatctactt ctttttaact
     2761 atatatctag cgcaacatga tgcccttggt atactgcatt tgttattgta gatgcacgaa
     2821 cacaatctcc aatttgagca acatatggag cacaatcaag taaagcgtct accacttctc
     2881 ttcttggttt ttgtccaagt gcacatatta ctgaagttcc tggaatattt attttattcc
     2941 cagatttatt catacatact acaccttctg ttgttacact taaaccttta tgctctgtat
     3001 atacatatat accttgtttt tctatttctt gtagtaatat tggacgattc cttatatttg
     3061 catccggggc aagttctgct ctcatctcta ctaagtgaac agtcttccct tcttgagcca
     3121 agtgaattgc agcctcacat cctgctaatc ctccacctaa aactactact tcatcagtta
     3181 ctttttcttt ttctaagtaa taatcattaa ctattactac attttctcca tcaagacctt
     3241 ctattgatgg aacaagaggt tcagacccta ctgctataat taatgcatca acattttcat
     3301 tttcaacata ttcttttgta actcttgtat ttaaacgtac ttcaacacct aaatcttctg
     3361 ctatttttcc aaaagtattt cctaattcgt acatttcata tttaaatgga agtgcttgtt
     3421 ctccttttaa aattccacct aattcattag tcttttcaca aagtattact ttatgcccac
     3481 gctttgcagc tgtaatagct gtttgtaacc ctcctggtcc accacctgct attaatactt
     3541 ttttaggttt taatactgga ataacttcag ttccatctaa ttcacgtcca ataagtggat
     3601 taacagtaca acgtcttgta gaagtggtag cacgttctgc catacaagtg aaacatctta
     3661 gacattttac tattttttca tcttgattac tcataacttt tcttggtaat tcgtggtcag
     3721 ctagtaatgc acgagccata taaataacat ctgcttttcc actagcaatt atctcttcca
     3781 tcatttctgg gtcatttaat gctcctatag tagcaactgg aatgtttaca tgttttttaa
     3841 tttcttctgc aagatataca ttacatccat gctctaagaa catagaagga tgtgttactg
     3901 caaatcctct ttgatatgta cctgctgata catgaagtaa atctactctt gattccaata
     3961 atttagcaat ttctactcca taatctaaat cgtatcctcc ctcaaataat tcagaaccac
     4021 tcattctaaa ctctattggg aatcctggac ctactgcttt acgaacacta tctaaaactt
     4081 ctttagcaaa acgaactcta ttttctaaag aaccaccata tttatcattt cttttgttaa
     4141 agtaaggtga taagaattga ttgattaacc atccatgtcc accatgaacc ataatcatct
     4201 caaaccctgc tcttttagcc aatgctgcaa catttccata cgattctact atttcagcaa
     4261 ttatttcttc tgtaagctct tttatctcta atccatcagg acgaacacta ggacttactc
     4321 cccactgtga taatcctcgc ttcttatctt tgtcaactaa ataagttcct gaatattgtc
     4381 ctgaatgaga taactctaca cttggtattg ctccatgacg acgaattgca tctgctgtgt
     4441 aagtaaaact tgctaaagag tcaactattt ttaaatctag atgatatgca tgtgaaccat
     4501 ctgtttctgg atgaaccata cattcgctaa ttgtaactgc acctgctcca ccttttgctc
     4561 ttagttcgta aaaggctgtt gattttgagc caattgtaca atctgctgtt atgtctgttc
     4621 ctcccatagg tgctgaaaac attctatttt tgaatgttac atttccaatt ttaattggct
     4681 tacatagatt tggatatttt cttttcatct tttatatctc ccttcattaa attttctatt
     4741 tttaaatttt gtattttatt tatatattta tataaaaatg ttaatataaa acctattaaa
     4801 gctataacta tagctataat gaaagccctt tgataattgc catctgtagc atatacattt
     4861 ttcataactg caggtccaac atatcctgca aaagcaaatc caataaacat gattccataa
     4921 tttacactat tatttttagg tccaaattta tctactgtaa atcctgggaa aattcccata
     4981 aatgaaccaa agcatatacc tataattatt attccaatat agaacgttgc tacatctcct
     5041 tctcttgaga ataataaaca taataaacca aaaattgaaa taactaatgc acctgctaaa
     5101 gtatttattc taccaatttt atctgagata taccctgcaa caatacggcc taatgtatta
     5161 aatagggcta aaattgaaac tactattgct gcatctgaac ttgtcatacc aatcatattt
     5221 gttgctagag aagatgctaa tgacacacac attaatccat agaaagctcc acaagttaat
     5281 attataatca ttagataaaa tataggtgtt gaaagcattt ctttccaatt cttattaata
     5341 ataactctta cttttccttt tttttctggt ggtatccatc cttctggtgt gaaatctgct
     5401 ggacattttt taataaagaa agaagaaaca catacaatta taagaaatac taaacctatt
     5461 gatttaaatg cagaggttac tccatattta ttaattatcc aattagcaac tggaggcatt
     5521 attactgaac taaacccata agctgctgtt gttataccac caactaatcc acttttatct
     5581 ggaaaaaatt taattgaatt acttattgtg catccataaa ccatgccaac cccaagacct
     5641 gttattatcc catatgataa aatcaacata ggtaatcctt ttgaaaaacc tgccaatatc
     5701 atacctatac caaaaactaa tcctcctaca aatacaacct ttttaggacc aaatttatca
     5761 tttatcattc cccctgtaat catagtaata ggtccaactg agtttgtaac tgtaaataca
     5821 attgctaaac tagcagctgt aaaagtcgtt ccagcaatac tatttaaatg ttctgccata
     5881 ggtgatgcaa atacactcca tgcatatatt gagccaatac ataaattaat gaaacaactt
     5941 gcaattaata taatccatct tttttgtgtt aaattcatta ttctcctcct ctataaattt
     6001 attaaatgga atttcttagt taagattatc acaatttttt ctatatgtaa atataaacat
     6061 gtaaatattt acatgtttat atttacataa tttctttttt atatatagct ttatttattt
     6121 ttattactca taatttacaa gttcttatta aaacatagtt atattaatta attcaaatta
     6181 aatatatcgt gttataataa gtatgtaatt aaagaaagag gtgtatttat gcgaacttta
     6241 aagtatgcaa ttttaggatt attaaataga aatcctatga ctggttatga tatcgtaaaa
     6301 gagttcaatt ttcaattagc tgagttttgg aatgcaaagc atagtcaaat atatcctgaa
     6361 ctaaaaaagc tggtaaatga aaagcttatt gtctatgata ttaaaattag tggtgatgta
     6421 ttagaaaaaa agttatacac aatcacagaa aaaggtaaag atgagttctt gaaatggctt
     6481 gaaaaggatg agccaatgga aagaactcct aaggatattt ttcgtcttag gatgtacttt
     6541 tctaataatt tagatataga tactaggctt attttactag agcatcagtt gcttcaacac
     6601 caagaaagaa ttgcgttctt atacagtcaa atggaacgtt atagtgaagt tcctcctctt
     6661 aatagtaatg attttggtga ttatatagtt cttgatggag ctattatcag agaacaaggt
     6721 gctataaaat ggctaacaaa ttgtattaac catcataaaa atttggataa tactactttg
     6781 aaataataac ttgttgattt taatagtgaa tttaattata gatattaaat ttataaaaaa
     6841 gactgtacac aactttgtct ttgtatacag tcttctatgg ttgattattc aaaatagcta
     6901 attataaaag ttaagtattt tttattaagc tattatttta tcttcttatt acctttcaaa
     6961 atctccttta tatttacaat ctttcacagt cgaattgcta tctcttctca taatacaaat
     7021 ccagttgatg tattgttact aagtttaatg gtaatcaaat tctttaccaa taagtataaa
     7081 aattactaat gtgttataat tttcttaact actaaatttt acatgcattt gaatagaata
     7141 tgtcaataaa ttactataat aaataaaaaa ttaagagtta aaataaaaaa tagttaggga
     7201 gatattatta tgattttata ttttagcggt actggtaata gccgatatgt agctcgtaaa
     7261 attgcacaag aattaaatga tgaacttata tcactaaatc aacttataaa agaagaaaaa
     7321 acagatgaat taatatcagc agataaacca ttcatattcg tatgtcctac ttatgcatgg
     7381 agattgccaa tagtggttac ggattttata aaaaaaacaa aatttctagg aagcaacaga
     7441 gtttactttg taatgacttg tggaggagat acagcaaaat ctataaacta tattcaaaaa
     7501 ctatgtaaat ataaggaatg gcaattaaaa ggtatggcag aaattaaaat gccagagaat
     7561 tatatagctt tattttctac aacagataaa gaaacatcaa aacaaatgat taaagaagca
     7621 gataaacaaa tatataggat tatttctgat atacgcaatg aaaatgaatt tgaaactatt
     7681 actcctagtg gcttaggagg tgcaattaaa agtggtataa taaatacagt tttttataag
     7741 acaattatta gtgccaaagg atttcattat actgacaaat gcattggctg tggaaaatgt
     7801 gtagagctat gtcctttaaa taatattaat ttaaaaaaca aaaagccagt ttggaaaaat
     7861 aactgcaccc attgtatggc atgtatttgt ggttgcccca ctgaagctat tgagtataaa
     7921 aataaaactc aaaatagaga aagatactat ttagaataat atattcttaa tatttaaacc
     7981 attataaaat gaactatacc cattgtttta tacagtttta catattttaa ctgtctcatg
     8041 ggtatagttc aaaagatagt gtctcaaagt gaacttttta gttcctaaat cactcttttt
     8101 tattaaatca agtatacttt aatcaccttt tcttatatca ttttcactaa tatgttgtat
     8161 tccaacaaat ataagattta ttagctctgt tagtgacttc cattgtgatt tttttgaatc
     8221 aagataataa tagtttttcg ttccttctct acgcacatta acaatctctg cttcttttag
     8281 tatcttaaga tgatgagata cggcaggacg agaaagatgt gttttttctg tgatttctcc
     8341 cactcgtata ccattaaaat cactctctaa gagagtaatt aaaatcaact gtctagtctc
     8401 atcacccata gcagagatag ctttgcgaca ttctttaaat ttagacgtta tttcttgcat
     8461 tctttgttga cattcttttt ccataaactc caccctctct tataagtatc taacatttgc
     8521 tgcttctttc tgtgcagtac gtctgtattt aacatctggg tatccaatta ctagtgttgt
     8581 aagaacatga ttactgcgtt ttagacctaa aagctttttt aactttggcg aattatttgc
     8641 tacatctgaa aaatatccac taaataaaac tcctagacca taagactctg ccattagtga
     8701 catatttgat gctgcaagtg aaccactaat cttatctttt gtaattatca ttattgcaat
     8761 aggagcattc ttaaagaaaa atttatcatc aatctcaact tcctttgaat atttaatagc
     8821 tatatttgca ataggtttta tttttctaaa aaatttcact gcttcgtttt cataaattga
     8881 ctttttattg tctaaaacaa tatatgatac atcttgtgaa tttttagcac taggggtata
     8941 cctacctgcc tcaataattt gctttacaat ttctaaagaa acttctttgt ctttaaattt
     9001 acggatactt cttctagatt taattgccat taataattca tctgaatcta gatttggctt
     9061 atttgtaagt tctattggag gttcatcaaa tcctgtcagt gtaatagctt tttggggaca
     9121 gattgctgca caatgcccac acattagaca atcttgtttt ttaattactg actttttatt
     9181 ttctataatt atattgttta ctggacaatc atttttacaa agcccacatc caatacaaag
     9241 ctctttgtca acttttatta tatgttggta tttcatattc attcatctac ctttcgttca
     9301 ttggtttaaa ctattataac acatagatat tttttatatt cattggtaaa gaatttgatt
     9361 accattaaat ttttaatctc tctattacac aaatttttca tagaatttta aaatatcata
     9421 gtttatacat aataaaaaag acaagcttaa aacctaagct cgcctttctc ataattttaa
     9481 tacaaagtaa atttcactta cttcccatac ttcctaacaa ttttattctt taaaatttta
     9541 tttgtgaatc atactatcca taaagtacaa cctaaaataa tcctgtgtta attttctata
     9601 gttaaaaaaa gttaaaaatt atacttaatt attaattttt atactcttct tatttaattt
     9661 aatacaagtt tcttatttaa tataaatttc ttgtctaata taaatcttca ccatttgaag
     9721 caattacttt cttataccat tcaaagcttt tctttttcgt tcttcttaaa cttccattac
     9781 cactattatc tctgtctaca tatataaatc cataacgctt ttccatttca cctgtaccag
     9841 cacttactaa atcaataggt gcccatgtag tataacctaa taaatcgaca ccatctatgt
     9901 aaactgcatc atgcatagct tttatatgtt ctcttagata atcaattctg taatcatctt
     9961 ctacataacc attttcgtca gctatatctt tagcacctaa tccattttct acaataaata
    10021 gtggcttttc atatctgtca tatacatgat ttaatgtaat tcttaaacct agtgggtcaa
    10081 ttggccatcc ccattgacta tatgaaagat atggattttt agcagatgta aatatgtttc
    10141 cttcagccat atcacctgca ttttcatcag ttctaacaca acggctattg taatatgaaa
    10201 atgaaataaa atctactgta tatttattta ataattcaat atcaccagat tccatttctg
    10261 gtgcaatacc tttttgctcc atatacttta atgcatagtt agggtattta cctttagatt
    10321 gtacatccac aaagaagtaa ttttctctat ctaactttgt agcttcccat acatcattag
    10381 gattgcaact ataaggatat acacttccag ctgcaaacat acatccaact aagttatttg
    10441 aatcaatttc atgtgctatt ttagttgcaa ttgcactagc tacaagttca tgatgagcag
    10501 cttgatattt tatcttttca acatcttcac cttcttcaaa gcaaatacca gcacccataa
    10561 atggagcatg taaaatcata tttatttcat taaaagttag ccagtacttc actaatcctt
    10621 tatatcttct aaagataaca ttgcataatt tctcatagaa acctatcatt ttacgattac
    10681 gccatgcacc atacttttta actaaatgca ttggacaatc aaagtgtgta atagtgacta
    10741 atggctctat tttatatttt ttacattcct taaatatatt ttcataaaat tgaagtccct
    10801 tttcatttgg tgtttcttca tcacctcttg gaaatattct actccatgca atgctcattc
    10861 tatatacttt aaatcccatt tcagcaaata actttatatc ttctttataa ttatggtaca
    10921 tatcaatacc agttttagct ggataataat gcttatcatc aaaatcgaac atttttagtt
    10981 ttcctgtaat aactgctgtt ctatcttttc ctgttgggca tacatctaca tttgccaatc
    11041 ctctttcgtc ttcattatat ccaccttcac attgattggc tgcagtagct cctccccata
    11101 aaaaatcatt cttaaaactc atagtcaaag cctcctaaaa ttataaccaa ttcactagct
    11161 tatactaatg ccttaatttt tactaaaata agaccgtaat tagattatcc tctaattcaa
    11221 tattttttct tcctgtttct actacatcta aaaattgtga tgaatttgta ataacaattg
    11281 gagttacaac actatatcct aactctttta ttgcatcaat gtcaaaattt aatatagttt
    11341 gaccttttgt aattctatca ccttgtttta tacatgcctc aaaacatctt ccctctaact
    11401 gaatagtatt taatccaata tgaataagca cttcaacacc tgcatctgaa agaatcccta
    11461 tagcatgtag actaggaaat aaggttgtaa ctactccatc tactggagca actacttttc
    11521 catcactagg tattattgct accccttgac ctagtacacc agatgcaaat gctgcatcct
    11581 ctatctcact taattttaat acttcacctt ttatagggct tgctactatt tctctttcta
    11641 atttagtaga cttgacttct tttatttctt ctttcccctt atttcttact tttttagact
    11701 cttctacttt ctcatcttta tataaaatca tagttaatac aaaagctacg accattgata
    11761 tagctatacc agaaagagct actattaagt tacccattcc tccatctggt tcaatcattg
    11821 ctggaagttc aaatattccc atacctccag ttataaactt tctaagatta aagaatccat
    11881 aaaaagctcc tccaatacca ctagcaatac aacttattat aaatggtttc tttaaaggta
    11941 ataatattcc ataaattgct ggctctgtaa ctccaaatat accagatata aagtttggta
    12001 ttgccatctc ttttagtttt ttatctttag tcttaaagaa tattgccaac acaactgctg
    12061 aacttgcaaa tgtacaagca aagaatggca tcataacatt atcatatcct aaagtcataa
    12121 cattgtttat atatacagga ataaatcccc agtgcatacc aaaaataaca agaatttgcc
    12181 acgtaaatcc tactatagca cctgctaata gtggactaaa atctctgatt gaaattacaa
    12241 cttgtgaaat aactgtagaa ccaaatgttg ctataggacc cagaacgata agtgcaacag
    12301 gcactgttat taataatgta agcattggca caaagaaaaa cttaactaaa tctggaataa
    12361 acttattaaa taatttttca cacctagatg caaaatacac tataaatata attggtacaa
    12421 ctgttccagt ataatcaatt gatacaattg gtagaccaaa gaaatcaata tatactggtg
    12481 atgcaaacat tgttccttta aataaagtgt acatcacatc tgctcctgct gatatactgc
    12541 taccttgtat agcaggataa catactgcag ctcctagtgc taatcccaac attggtttta
    12601 atccaaactt cttagctgaa gtatatccta aaaacaaagg aaggaatgta aataatgcat
    12661 ctcctgctgc atttattacc atataaccac cagatacatc actatataac cccattgcta
    12721 caaataatgc attaaatcct ttcaacatac cacaagctgc cattattcct aatactggct
    12781 gaaaaattcc tgatattata tctataccct tatcgagtat actacctgat tttttagttt
    12841 ctgaatttgc acttgagtta tctaaaccaa ttatttcaac tacatcttta tagacagcct
    12901 caacatgatt tcctataact acttgatatt gtcctccact tttcattaca gtaacaatac
    12961 cttccatatt ttttaataca ttgtcatttg ctatactttc atcttttaaa gtaaaacgta
    13021 atcttgtaat gcagtgtact aatccactaa tattttcttt tccaccaaca ttttttacta
    13081 tctcttgtgc taattgtttg tattttccca tttttctcct ccatatttcg tttaaattaa
    13141 tttttgaaat ttgaaggttt ggccaactca atgttaccat ccaaccatag gtataatttt
    13201 gttaatatca ctcctttcaa taacatttac tatatactac tgaaaattaa tttacttata
    13261 tatttgaatc tttaactact tttgctaaat gtattgttaa atatataagc tcatcatctg
    13321 ttaatatgta gttatattgt tttttaataa aatccttaat cttaactaca cattcaaact
    13381 ctttattata tttagattta ataatactta ataattcttt atctgtccca ccttcatgtg
    13441 cattatttaa aagtaatctc tgtgcaaaaa atttcaaatg cattataaat ctataataaa
    13501 acactgattc ttcatgaaat tctatcctaa aatgatacct aactatacta agtacttctt
    13561 gtattaactt tgtaatatca gatgcaaaag tatgcccctc acttagctga gcattcacta
    13621 tatgaaaagc tataaatcca gcctcatctt caggtaattt tacgcctgtt ttattttcaa
    13681 taatatctag tgccttcatt ccaatttcaa actcttcttt ataaaatctt ttaatttccc
    13741 aaaggattgc attttttaca tttattcctt ctttcattct ttgaattgca gaatatgtat
    13801 ggtcacttaa ggatatgtaa atgctttcat ttagcttctt gtttaacttt atttgtgcat
    13861 actctataat ttcacttgat aatttcatgt gctctatagg aatattattg agtaattctt
    13921 gtagtttgtt tgatacttct ttatttgata ttctaaatac tttgtttact ttagttttat
    13981 ctattagatt gccttttgat ttttgataac caattccttt acccatgacg ataatttctt
    14041 catcattatc atctaatgtg attacaacat tattgtttaa tatcttatta attatcatga
    14101 ttatcctcct tttaagcata aaaaaaactt atccataata atgggcatac tccttcctag
    14161 gatactgcta ttattaatga ataagcttag cttgtactta aacaattact acctaattcc
    14221 aattactatg ataaaacatc atacatattt tgtcaacttt ttatttccat ataaatagat
    14281 ttactacacc ttctgttata agtaatattt ctatttcttt atgccagtgt ggtgttgtta
    14341 atacttctcc ttcatttgat agactacgaa aaggaaattc atgtattaat ttaggcattt
    14401 ctaaatatat tgccatatat atcctctcct ttctagtgtc taaaaattaa tatatactat
    14461 ttaaaataat acatacttta ttttaaaaac ctcaaaatta taatttatac aatacctaca
    14521 cttcataaaa tatatctaat atttcttttt ttgtatttgc atttaaaagt ctttcactta
    14581 tatctttacc tcctaaaata tacgctattt tagatattaa tgtcatatct tcattgtctc
    14641 cagattgtgg catagcaaac ataattatta cctttacagg taagccatct atacttggcc
    14701 aatctatacc ttttttagat ttacctatta ccacagatgc cttctttaca tattttgttt
    14761 ttccatgtgg catggccatt tgataaccta tactagtaga gcctattttt tctctacgtt
    14821 ttagtgcctt tataaactta ctttttaaat ctatacttcc tgtatcgtat aatttatcta
    14881 ccaactcttg tatgatacct tcttttgtag ttgatttcaa atctaaaata atactttctt
    14941 cgcttaatat ttctctaatt tccatttgtt ttctccagta gattattttt aaataatatt
    15001 ttaatatcct ctttgctctt gcaatctatt atatagttta tataactctt ttgcctatat
    15061 aaatttgata tttccattaa aatattcttt aaaaaacttt gattactagt ttctaaataa
    15121 atatcaattg ttctattaat attattgaca ttcattatcc ctttatttag tttactttga
    15181 ttatgtatat atatatttaa atcctttcct aatgaaatag atttatattt actccctaaa
    15241 tccacgccta ttaaactttc catctgcatt acatcaaaat taaaatatat attatcttct
    15301 aaatacattc ctaataagtt tgtatctaag ttcatacttt tcttaggttt agaaagtaag
    15361 gcatttttta tattactaat atcactttcc attaatagta ctgatacaac tatatgtaat
    15421 ttatctttca agtctaggtt tacagtagat attacaaagt ctacatcatc taaatttcga
    15481 ttgctcaact gatgcatagg aactatatca actatagtcc attcaggaaa ttctcttttt
    15541 aatctggctg caagtagctg agatgttcca taacctgtat gacaaactac tattactctt
    15601 ttactactca tatttctctc tattgctgct tgaaaatatg tggcaagata cgaaacttca
    15661 tctatactaa tgttcttcag attatcatac tctgtcataa tatttatagt catcatacat
    15721 aatcccaaca catctgaaaa tcgctcttgt atctctccta ataatggatt ttttatttgg
    15781 atatcatatc ttaatctgtt taacataggt cttacatgag atgctagact tttttgtagt
    15841 aagtcatcat ttttgagatt tatatttaaa aattgcgaca tattctctat cattatagat
    15901 gaaaactttt cactttcact taatctatat gattcatcat tgtaactatt attactttcg
    15961 ctactaaatc cagatgacac taaaaaaata tatatgtaca taatttcatc tttcgttatt
    16021 tttactccgt atctattttc tattttgcct ataagtgcag tgacattttg atatactaat
    16081 tcatccaaat tatctacaga aacttctctt tcttcctgag actctatttg attaccttct
    16141 tcgattctct ttaaacatat aagtatatgg gtaattaaat ttatatagta gggctgactt
    16201 atagtgtatc ctaaattgta ttctaactct gtaattatag tttctacaaa tataatagaa
    16261 tcaatatcaa ataaatttat caacgcacta aatgtagcag aatctaatct tgttaactta
    16321 gatatatcat gctgttcata attttcatct aataaatcat ccatcatttt ggcaatcgat
    16381 ttccttatat ccacttcttt acctataatc ttagttccct ctaaagtttt attaagtttc
    16441 aaattgtatt cttttatcca tgcctctata tatttaaaat catttactat agaagtttta
    16501 ctcacataat atttatctgc taactgattt attgaagtta tattatttga atttagtaat
    16561 aaatacttta aaatctccat tcttctctgt tctactgata aagatttatt ttccttcgat
    16621 tgtatattta aactattaat taagtctata ttcttctttg ccaaagattc tattaatatt
    16681 ccatatcctc tttttatatc aatttttata ttaaaagttt ctaagtattt ctcaataatc
    16741 ttcaaatctt tttgtaaagt tttatcggat acatttaatt tatctttaaa gtattttata
    16801 ggtctatatt tattttcgtt taatatcaat ttaagaaatt caatttgcct cgacacaagc
    16861 atacttatcc ctccctacct atgtttatat atttctatgt tcatattaag tactatttta
    16921 acatatttac taactatgta aaattactaa gatacttctg tatcataaaa gaatttatga
    16981 tacaccttat taaattgata taatagaaat ataatttcaa aataaaaaat aaggatattt
    17041 agaagtagtt aactaattct aaatatcctt atttttattc tatgtacttg tggttattct
    17101 attacttatt tttactatca tttataattt aagccccaag tacttcaact tcactatttt
    17161 cactccttat agtaggcttt gttaccccta taatcaatgc tgttattact gttccaatca
    17221 atatacaagc tatatatgca actggtgaac tacatgcaaa tggtattaca aatattcccc
    17281 catgtggtgc cattaaagtt atatctaaac tcatacatat tgccccacct atacaagaac
    17341 caattatatt tgctggaatc attcttaatg ggtctgcagc tgcaaacggt attgctcctt
    17401 ctgttatgaa agatgctccc attatagcag ttggtagaga tgactttctt tcttctttag
    17461 taaacttatt tttgaatatc aacatagcta atgatatcgc taatggaggt accattcctc
    17521 ctaccattaa agctgctgat ggttcaaata tattacttga aaacatagcc aatccaaaag
    17581 ctgaagccgt tttgttaata ggccctccca tatctgatgc catcattcct gctaatattg
    17641 cacctaataa tactttatta gttccagaca tgctttgtaa ccaagattgt aaagcttcat
    17701 ttaaccatga tgctggtgta ttaactacaa agaacattat agctccactt gtaaatgcaa
    17761 tcaacagtgg acatatcaat acagcattta ctccttttaa tacatctggt aaattttctg
    17821 ttatcttcat tactcccaag gctatatatc ctgttgaaaa acctgccacc ataccaccta
    17881 taaaccctga acctccaata actgccataa aaccagctat catagcagga gcaaaacctt
    17941 gtcttcctgc tattgattta gctataaaac cagcaagtat aggtataaat aacttaaatg
    18001 ctgaatctcc tccaagttgt ccaaagaatc cagctatagg gttgtatgtt tcatgagttg
    18061 ggtctgatgc aaatatccca aacataaatg ctatggctat accaattcca cctattacta
    18121 caaatggaat catttcggat acaccactca ttaagtgctt ataaacacct tttttctctg
    18181 acccttggag tatttctttt gaatcttcta aagttcttcc acctggttta atttctttag
    18241 ccattccatt ttcagcattt ataattaaat ttttagctaa tgaaacattc ttagcatctg
    18301 ctactttctt ttgtaacact ttctttccta taaatctact catttgaact tctttatcac
    18361 aagctattat tacgtattca gctcttttta tatcttcttt agtcaactta ttttctacac
    18421 ctatcgctcc atgagtttct atcttaactt catatccaag ttcttgcccc gcttcctcta
    18481 atgctttttt tgccataaaa gtgtgagcta tccctgttgg gcatcctgtt attccaacta
    18541 taagaccttt attttgatta tcacttgaat ctcctgattc tacagcttta ttattaaata
    18601 tacttaatat ttcatatgga gtttctgcac ttagtaggtg cttaagaaga ttttcatcca
    18661 ttagatatgt agctagttta gatataatct taagatgttc atctgagcct gactctggaa
    18721 ctgctatcat aaaaaatgac ctaagttttt gaccatcatt atccgtaatt tccttatcag
    18781 ttcttaaata catcattaca ggttgattta ctacatttga cttagcatga ggtatagcta
    18841 ttaaattacc catattagtt gatgattctt tttcacgttt attaatatca actataaact
    18901 tttctttatc atttatataa ttcccatggt acaaatgatt tgccatataa tcaatcacat
    18961 ctttttttgt ttgtaattgt ttatctagta caatacaatc gcttcgtagt atttgaccta
    19021 tcataaattc tcccctcctt tttatttgtt accttataat taattcttgt ttttataaaa
    19081 gcactttaat ttatctatgg tattgaatag attcatttta aactctataa cttctcttgc
    19141 agcatctata catggtggat atatagtgtc tggctcatat aagcttgaat ttttttctaa
    19201 tacttctctg cacttcttat aatatgccga cttaacatca cttgaaatat ttattttaca
    19261 aactcctagt ttaactgctt gtgctatttc ttcatctgga tttgatgaac caccatggag
    19321 aactaaaggt atatctacta cttctcttat ttcttttaat aaatctagtt taagctctgg
    19381 tttaaaacct tttggatata taccatgtgc tgtaccaatt gcaatagcta gtgtgtctac
    19441 tcctgttttt tcaataaaat ctttagctaa ttttgaatct gtatatatta tttcatcagt
    19501 accaccttca cttgatgttc ctgttgttcc tattgttcca agctctcctt ctacagatac
    19561 atttaatcct tttgctattt ctactacttc cctagatata gctacattct cttcatatgg
    19621 taaatgtgag ccatcaatca ttactgatgt aaatccacat cttattgctc ttaatatttg
    19681 ttctttattt tccccatgat ctaagtgtat taccataggt actttgctct tatttgcttc
    19741 ttctatacaa ctagctacaa agctatcccc taggaagctt agctcatttg ggtgtattgc
    19801 aaggattact ggtgcatttt tttcgttagc actctgtact actgctttaa gtatttgccc
    19861 acttcctata ttaaatgctg gcacagcaaa ttgattttct tgtgccactt ttagcatttc
    19921 cttcatattt attaacatat tatacctccc gatattttaa attttaggtt gaatttgatt
    19981 cttgttaatt ttgttgttgt ttatatttaa ataatatcag ggtaatgacg gttcgaaaat
    20041 aacaatcgtt ttccttagtg aaaaggaact tttattatac actcttagtt ccttttcact
    20101 aaataatttt tagaagtctt tatcatagtt aattatacct ctcatgtaca tcttttcgtc
    20161 ttaagcgttt taatttaata ggctttaacc ttactatatt tttataataa acaattaaga
    20221 tactttaact ataaatttaa agatactcat gcaatagtta atgttatatt agagtcaaaa
    20281 aaattaaaaa gatattagct atttagccaa taccttttcg tggatttcaa tagtatatac
    20341 gatttatatg aatcatactc acgcttatct aatgttttac ttccataaac tttacacaaa
    20401 acaccaaaat gacaccctcc aaattcatct ctagctaata aagtgatttg gttttctaag
    20461 caccaattta taaattaacc tttattatct tatgtaaatc tttttctatc taatttaaaa
    20521 attattccta atgctatata gcatatacca attactaata caccataagc catagatact
    20581 cctatcttaa attcttgcat attagttaca atagaaattg aaataggtct attataaaca
    20641 ccataaagca aggctgacat tgtatattcc ccaattgtac gaatgaatac taatatagct
    20701 cctgaaatta ttcctggcat catatttggt actattacat tataaaaggt ttttatcctt
    20761 ccagcaccta aactccttga tgattcttct agtcctaaat ttattgactt catagcaacc
    20821 tcattggatg aaaataataa tggtagggca taaattgtat atgctatagg tacaatataa
    20881 aaacctccta ttaaggattc attaaaagca aatatacttt tttgattaaa tgtattaatt
    20941 aggttaactg caatggcgct tgcaggcata ctccaaggta gcattataat aaattttgct
    21001 agtcgattat atgtagtatc cttcttaatt actaaatacg atactggtat agtgattatc
    21061 aatcctatta ctactgccat taaagacatt ttcaagctgt ttaatatagg ctgtaacaca
    21121 cgtgattttt ggaaaatcat ctgatagttt tccagtgtaa agtctctagg aaatatagtt
    21181 gtcataattg aatgtgtgct tacaaaggat aaatacacaa tagtaactat aggaagcatg
    21241 atcataacaa tttgtatttc aataataacc ttacatacaa atgtaaataa gtcttttttt
    21301 ctattatgaa ctttataacc ttgagacttt aaggatgcta ctactccata tttttttcca
    21361 tagtactgta ataaaatcat aaatgaaatc cccattagta acaaaataat tacttgaact
    21421 gaagctatat ccatgtggtt attagcctta gacctaacaa tctgagtgct taaaacttta
    21481 aaaccaccac ctataagatt tggtgctgag aaagaactaa tacctgatgc aaaagttata
    21541 atagtagagg ttataatggc aggtgtaata acaggccata ttacatcaaa aaatactctt
    21601 atctttgatg ctcccattcc ttttgcagct tcaactgttg aataatccac atattttaag
    21661 gcaacatata catttaaata aaaatacaca tactgagtat aggcaaccac aaataaaact
    21721 ccctttaatc cactaaaatc ataaggtttt ttgataaagg atagtaaaat ttctatagat
    21781 tttgtgacta tcccactttc tccataaagc tgaatacatg caattaccat aattactcca
    21841 ggaatcatca ttggacttag taaaagaata tgtatgattt tcttgtgttt atcacaaaca
    21901 aatgtcatat ataaggcaag tgatattccc ataattccac atacgagtac agaaccaaat
    21961 cccaaaatta tagtattgct tactaccttt aaattattag tatttgaaaa atattcttta
    22021 aaaacttcaa aagaatatcc acctttacct tgaaatgctt gtgtaaaggt attgcctatt
    22081 ggtatgataa tatatccaat caaaatccaa aataatatac tgtataaaat aatcgaaata
    22141 acatttttag gtgtaaattt actacgtttt atttttttaa tcatattagt taccttgtag
    22201 cacacctaaa tatgccatat cccctacgtt taatttattg ctattattca gtctattaag
    22261 ttcagttact tgatattttt ttccattatt tgatactgta tattctaaaa ttgctcctaa
    22321 gaaattctta gattctactt ttacttttat aaaaccactt tggttggtat tttgcaataa
    22381 taccatttct tcaggtcttt tataaatata aggctttgtc tctttttcaa tattaaaatt
    22441 aacataatct tctttttcaa tacagtttga agtacctaca aagtttgcta caaagtcatt
    22501 caatggtttt ttgtaaactt ccattggaac accaatttga agaaccttcc ccttatccat
    22561 tacagctatt ctatcagaaa tagctaaggc ttcctgttga tcatgagtaa taaataaagt
    22621 agtaatacct atcttttgtt gtatctctct tatttcttcc ctcatcttga ttcttaaagc
    22681 tatatctaga ttagacattg gctcatctaa taaaagcata gtaggttcag tcgctaatga
    22741 ccttgctact gccacccttt gttgctgtcc accagataac tcatcaatct tttttttcct
    22801 aaaatctttc attcctgcca gctctaaata attatcacat ttttccttta taattttttt
    22861 agacagtttt tttattttca atccataaga tacattttct tcaactgtca tatttggaaa
    22921 cagtgcatag ttttgaaaaa cagttcccat atttctattt tctggttcta aattggtaat
    22981 atttttatca ccaacataaa tacttccaga agaaggtttt ataaatccac caattattct
    23041 taaaatagtc gtttttccac atccagaagg acctagtaaa gtaaaaaact ctccttcctt
    23101 aatagatata ttaatatcat ataatacttt ttcttttcca taataatgat taatttcttt
    23161 taattctata ttcttcatat cgtctccaca aattatctaa tatttataaa tctccaaata
    23221 tacacatgac gaatcatcat agattttaaa tctaggaaac tctattgcca tttcatcatc
    23281 cttttctagt tccctaacct ttctatatat ataatctata cctttaatct ctgctatttt
    23341 catcatttca tttttatcaa aaatcttata tctatcatat ccacatgaaa aaccatcact
    23401 agccatcata attttcattt tatattctat atcaataaat ccacttatac aattatcaac
    23461 agcctcttta gaaaattcca aagcccaata tccacctaca gtatttttct taagtctatt
    23521 ctctattata atcggcatta cctcggcttt tctctccttt aaagtaaggt ttgtaacatc
    23581 tttggcttct tgcataaaat caaatatttt tttatcaagt ctacataaag tctcatcttt
    23641 taaaattttc acagattcat tatggttaac taataaagta caatctccta aaagtaaata
    23701 ctctatctta tctttataaa actttaatat agaacatgaa caagaaggaa tatctattgc
    23761 ttctacttct ttatcatatg ttaatttgta gtactctttt gttatctcct caatgccttc
    23821 tttaataatc acttttaagc tatcttctct ttccatattc tcatgaaggt aactattcca
    23881 ccaacttaca taccatttag catcactttc tgtagagact aaattcttat tatttaaacc
    23941 tgtagctcca tcaagtaccc atgccccata aggtgataaa cctacgatat cttcgttaaa
    24001 atcgccatta cctttattac ataataattt ataatcacta atttttagtc ccatctttat
    24061 ctccttgccc acataaattg tacttttact ataattaaaa gttttacata ataaaaaatt
    24121 tactttattt aagaaactat gtctacaaat cactttatat agtcaattac ttcgttagtt
    24181 gctcaaaaac tattttattt aataaatatg tattagtatc atttgttgta tgaattataa
    24241 aaaattatga gatgctatag ttcccttata agtaaaatag cgaggaaaat cctcactatt
    24301 tttgtatata atattaaatt atttaattaa gctattttat agttttatta ttatctatta
    24361 tatctgtttc ccacttttca atccagttag actgattttt tccaattaca gaccaatcta
    24421 catccatagc tttatattct tttgacatcc actttggtga atctttaagt gcagaatcta
    24481 atgttggaat acgattaaaa tcatttgcaa ccatagcttg aaccttagca cttccaacaa
    24541 aatctacaaa tttagctgct gcatttggat gtggtgcatt ttttagggct gctacacagt
    24601 ctgtgattac tacagaacca ctctctgcat ctacaacttc taatggcata ttattttttt
    24661 ctttattctc tattatatca cttaatactg caacagatat tgcagcttca cctttaccta
    24721 ttgctgaata catgacactt ccactattgt agtaattctt tatattttta tttaaatcct
    24781 caagatactt ccaagcttcc tcttcactct tagtatttga gtagtaattg attaagttac
    24841 taatagtaga acgcatagat gatgataatg agtctctagt aactattaaa tctttgtatt
    24901 cttcttttgt taaatcgctc caatcttttg gcactttatc agctgataat agttttgtgt
    24961 tgtaaaaaat cattactggt gtttttatag ttccatacca atatccatct gagtctttgt
    25021 aagacttgtc taattcatta ttccagcttg gtttagtctt ttcatataat ccttcttctt
    25081 ttaattgcat gtatgtagat gtatctccac caaacattat atctgcttgt ggattatctt
    25141 tttcacttct aacacggtct gctaattcac cttttaagtt tataaattca acattaactc
    25201 ctgtttcctt tgtaaattct tcagaaattg ctcctagcat atcctctcca tgtgtagtat
    25261 atactactaa tgtatcctct aatttatcac tttttgatgt gttatcattg ctacaagcta
    25321 caagtgataa taacattgct acagttaata aaacaactgc tatttttctc ttcatattga
    25381 ttcctccccc atattctcca tgttcatttt aaatgttatt attcttgtag tcaatgattc
    25441 aacaacaatc tatataattg tgtttttcta tagtcactta ttttattatt gtttttttct
    25501 ataattatac ctatttgtat gcatataatt tttatattca ccttaatcca ttttttagta
    25561 tgagtatttt tctatttaaa acacacttta aatattaata ttactatcat atcattattt
    25621 aaattgtacc catcttttaa cagataacta gataaaaata aatattgctt tatacttata
    25681 tcctttgatg tatcaatatt tgacaaatca gctttcccat tgctaataat ccctttgtat
    25741 attaattcat ctcattaatt taatatgtta tctttatttc tctataattc caagtcttta
    25801 catacattat aagctacatt tttaatctat ataatattct tatctcatta cttttatttt
    25861 ctctaaataa atgtatagct ccttatatat aatctaaatg tatatgtata gatacaataa
    25921 gatataaaga ttttttattc ttattcaatt ccactaattt agatttagta tgcttataat
    25981 aagtatcttt catttcacag tctataaata tattagtttc ttcaccatta ataattacta
    26041 aaaaactatc tccacaataa tcttaaaaca ttgtaatttt atactagttc atatattaat
    26101 tttctctaaa agctaaataa atttgtataa tattctatat attaaatcat atgtatccca
    26161 atttttaact ttacctcttc aaatttatat tcatttttaa taaaaaaata ttgactattt
    26221 agtcaatatc ttttagtaga tttaaatggt aaagactatc ctgagaatca tacccacgat
    26281 tttaatctaa tttttaatgg tttccttagc ataatcttat aaatattaaa atttatctac
    26341 ttataaaatt tctccattaa attttattac atttttatac caatcaaaag acttcttttt
    26401 atatctttta agagtcccac ttccatcatt atttttatct acatatataa atccatatct
    26461 ttttttcatt tctcctgttg taaatgacac tgggtctata catccccaaa cagtataccc
    26521 tataacatca actccatcaa tttcaatggc ctttttcatt tcccttatat gactagccaa
    26581 atactctatt ctataaccat catccacagt attatctgat tttaatacat cctctgctcc
    26641 aaatccattt tcaacaataa atataggaag ttcatactta tcatataatt gattaaggta
    26701 aaatcttaga cctacagggt ctatattcca cccccagtca gaagttttta agtatggatt
    26761 ttcaactaca tcagcctttc ctgccgagtc attacctgtt gttttcatag ttttatcagc
    26821 tgatactaca gtagttaaat aataactaca tccaataaaa tcaactgttc cttcttttag
    26881 gattttttta tcctcatctg taatatctaa attataattt tttctttccc ataattttag
    26941 tgtatgcctt ggataatgac ctcttacatg tacatcagta aacataagtt gttctctatt
    27001 agattctaca aatttaatca tatcctctgg attgcaagaa taaggataac ttggtatagc
    27061 tgccaccata catccaattt taaactctgg gtttatttca tgacctatct tcacaacctt
    27121 tgcacttgct acaaattcat aatgaactgc ttgatacata acttcttctt tgtcttcctg
    27181 ctcttcatag attattcccg agttagtaaa tgcataaata ggatttgtag ttatactttg
    27241 attatttatt tcattgaaag tcatccagta cttaacttta tccttgtatc tactcattac
    27301 cacttcacag aagtttacaa agaaatctat taattttcta ttcctccatc caccatagtt
    27361 tttcactaaa tgataaggca tttcaaaatg gcttaaagtt attactggct ctatattgta
    27421 ttttaataat tcatcaaata aatcatcata aaatttcaat ccatcttcat ttggaattga
    27481 ttcatctcca tttggaaaaa tcctagtcca agcaatactt gtcctaaaac acttatatcc
    27541 catttcagca aataatctaa tatcttcttt ataattttca taaaaattaa tggcttcatg
    27601 attaggataa tttaagccct caattactcc atctgttacc tttcttgaaa tagtatgagt
    27661 acctgcagtc atcacatctg caatacttat tccttttcct cctttattat atccaccttc
    27721 aacttgatgg gcagcaactg cccctcccca taaaaattct tgattagatt tcatagaaat
    27781 atctcctcca gtataattaa taaacaactt ttattacagg tgttccaatt ttaatatgtt
    27841 tattttcttt aactattaca tctgctaaat catttgtgtt ggttagtatt attggtgtaa
    27901 caatactata cccttcacct tctattttat ccttatcgaa agaaacaatc ttatctcctt
    27961 ttttaacttt atctcctgca ttcatatgag taatataata ctttccatct aacatagtag
    28021 tgttaagacc tacgtgtatt aatatttcta cacctttatc agaagtaatt cctattgcgt
    28081 gttttgtagg aaaaatagtt gttattgttc catctacagg agatacaact tctccttttg
    28141 aaggtattat tgccatgcca ttacctatag ttcctgatgc aaacacttca tcttctactt
    28201 cagataactc tatttgtaag ccttctattg gagataatat ttcctctata ccatcatctt
    28261 catcaaaagc aacttcttca ttaccttctt cacattcttc tttactcaat ccaaagaaat
    28321 atgacaatac tgctcctaac actagtgctg ttcctattcc taatatatat cctagaaatg
    28381 gtgtataaac tggcattgag aatatattat ggaatacata tgcattacaa gtaacgccaa
    28441 atacgccaca tataccacca ccaatacctc ctgcaatagc caatactgga atcatccttc
    28501 tgtatcttaa tataattcca taaattatag gttctgttac tcctgctaaa attcctgtaa
    28561 ctgctgttga acctgctaat acttttaatt ctgaattttt tttagatttt ctaaccttca
    28621 taaataaacc tattgcaata cctatttgag caaatactgc tgcaacagct gcaccttcta
    28681 ttgggtctcc acccattgta gccaaatttt gtaaagtaat tggcgtgaag ccccagtgta
    28741 atcctaatac tgctaagaat ggcatagcta tacctattgc agctcctgca attactctat
    28801 taaattcaaa taatcccata aaaatatttg atattacatc cccaacatta gttgctatcg
    28861 gtccaaataa aattacagtt aaaggaacca tgactaataa tgatatcatt ggcactaaga
    28921 acaattgtaa atcttttaat ataatcttct ttaaaagctt atcaacataa taataaataa
    28981 atatagcaac aaatatagga aagacaccaa aagaataatc aattgctgtt actggcattc
    29041 caaaaaagtt agcaccacct tttgctccaa ttaaagctgt aaaattagga tctaacaaag
    29101 ctgctcctat cactccacca acatagggat ttgcaccaag ctttatagct aaagtaatac
    29161 ctaagaatat tggtaaaaag taaaatacag catttccagc tgctgataat atagcataag
    29221 tgctacttgt atcagacatc catttcataa tagttaatat tgtaagcaat gccttaatca
    29281 tacctgctcc agctagtgca ggtattaatg gagaaaatgc acctgaaatt gattcaaata
    29341 ttctagaaac tattgaaact ttttctccct gttctccagt attttgaact tgtaaaacag
    29401 ctttttttgt aatagtttca aagtaatcag ttactttatt tcctattact acttggtatt
    29461 gtcctccact atttactaca gatagtacat ccttcatttt taataactct tctttgttag
    29521 tttttgaagt atctttcaac ttaaaacgta gcctagttgc acaatgaact aaactaataa
    29581 tattttcttt tcctccgaca tattttataa tctcttcaga ctctctttca aatttcatac
    29641 aatctatcct ccattttcat aattttatgt ataaaaatag acctaaatca atacaattag
    29701 atgttaaaaa ctaattatac caacttaggt catgcctgcc aaacagtaac aatcctacaa
    29761 tatttacttt atatttgata atctatttaa atgcaatgtt aagtacaaca attcattttc
    29821 gctaattttc catttatacg tcttttcaag aaagtttttt actttttttg cacaattgta
    29881 atcactttta tatttcattt ttattatatc taacaatgat gtgtctacat ttgcattctc
    29941 accacttaat tgccttttta taaaacacct taaatgactt ataaaccttg tgtagtcaaa
    30001 tgaatattca tttatttcaa ttccatagtg atactttatg atatctaata cattatcaat
    30061 tatcttagtt aacaataaag tttcttgcat atcttttgtt tctaactgag catttgcaaa
    30121 gtgtatcgta ataaatgcta tttcagaatc aggaatatct ttatctagtt tttttcttaa
    30181 atattctaca gctttcttac taaatttata ttcattagga tatatttgtc ttatttccca
    30241 ttgaagtggg ctttgaaata ctaatccttc atccattctt tttaacatgt aacttatatg
    30301 ttctgataat gtgattaata tactatcatt aagattatca cccaattcgt ctcttcccat
    30361 ttgaataatt tcacttacaa gctcaacatc ttttaaaggt atcctatcta gtagtgaatg
    30421 taattcactt aacgattcct cattattgaa tataaatttc ttttcaattt tatctatttc
    30481 aactaaatct ttagtaaatt tattaaatcc aattcctttt cccattaata ttacttcttg
    30541 tcctgaatta tctctggcaa atacaacatt attattaaat actttcttta taaccataaa
    30601 ctacctccaa tgtaaacaaa aagagaccta aaaaagacta ataatacttt aagcatttac
    30661 tagaattttt aggtcacgcc tgattacttc tatctcagta acgatccgtt tatttatctg
    30721 tatgataact ttattttcat tataaattaa taactgtact tagtcaatat ataattcatg
    30781 tatatatcta cctatattat tttcttcaat attcactcat tctacttttt ttcatataat
    30841 ttatataacc taaacatgct aaaataagtt ttgaagttat ttcataacaa aattaaactc
    30901 atatattgtt tactatatat gctcgattat ttatcaatat ataaggaaat cctttatttt
    30961 tgtaactaca ataactgact aagttttgat tttcttttat cttttacttc ttattattaa
    31021 aaaataattc ttttactgtt gtatctaaag ctttaaacag tttaatcatc aaatcattgt
    31081 ttggattatt aaccttacct aacttactat atagcttttt aactgcatat ctttaataga
    31141 ccttttggta tgctaatcca ttttataata ttaattcttg aatcaagcat atattaccct
    31201 tacaatgcat atcttatacc ctctgtaaag ttattcctga agaaattact cttacaagac
    31261 atatctgata caacctcact tataagttta tatgtttcag aagtatataa ataacccata
    31321 cttccttcca aactcttacc tgttttctta gaaaattcta atagatttcc ttacataaca
    31381 attgtaacag agtcttatta gatttcataa aactatacat cctctttaca tttaaacttt
    31441 aaacttttat ctattgttta tcaatcaaat gtatattcac tattttttat catttataat
    31501 actcttcttc ttatcttaaa acaattataa tctaacctta atcacatact atattatata
    31561 aatattttta acaaacttaa taattaaata actatatttt attatccatc ttataaatgt
    31621 ttataaactt tccactattc ttgttcaata aattcaaaca aattttctac tgtggtatcg
    31681 aatactttag cgatatccat agctaacttc aaagaaggat tatacttccc attttctaag
    31741 tgtacaatag tctcacgtct taccccaact aatttagcaa gttcattttg cgtcataagg
    31801 aatttttctc tgtattcttt aatttttgtt ttcatcaata ttgccactta gttacatatc
    31861 ccccttttat caaagtatat atacaacact aatttagata aagactgtat atataaaact
    31921 gcaatgagga ttatacctgt atctatgttt gatatattta tattacttgt ataaggtgtt
    31981 gcaaagaaaa tagatattat tactatagaa tatatcatta tttttattgc aattttatta
    32041 acctttgata gtataaattc agatgattca tcgactaaat cattatattt tttattataa
    32101 attgaataac atccaaaaac tattaaccaa ctcaaccctg gaagagaagc agtgcttgga
    32161 cctttaaaaa tatacttagt ggctaataca gctataaaaa aataagttat tacaagcaac
    32221 tccaggataa gctttgattt tacaccagtt tctgatttag acatataaaa tcactcctta
    32281 aaaattatat tctctatact ctttaatttt cgtttttatc aatattatca cttagttgca
    32341 tattcccttt ttatcaaaat atatatacaa aattaattta gataaagatt gtatatataa
    32401 aatagctaag agaattacac ctatatccaa atttgatata tccaaacctc ttgtataatt
    32461 tgcttaaaag aaaacagcta ttagaaaaat agaatataac attatttttg atgcaatatg
    32521 atcaaccttt aataacataa gttttgatgc ctcatcaact aaatcattat attttttatt
    32581 atacatgaag tcacatgccc caaaatcgaa taaaattata aaagtaattc aaatatttcc
    32641 ccctttaaaa taaacttttt taataatgaa tctataaaaa ataggatatc ataagtagct
    32701 ttgaaacaag atttgtttta aatccaagct ctgatttaga catataaact ccttaaaagt
    32761 tatatattta taacacctta tgttataaat atataacttt tccaaataaa ttgcaataga
    32821 atatcgtaaa tattcaataa tatctttata aatatagttt ataaaggatt ttataataaa
    32881 cattgcaata cagtactaaa ttagtttatt gcatatatta tttcaatcat atcatttact
    32941 aactattatt ctaatgagca tataacattg aaatttataa ttatacaacc taaatgcatc
    33001 ccaatgtacc ctcaaaacct tcattttctg taactgaagt ataattggta gattttatca
    33061 ctgaaataaa aaacactagt caataaagac tagtattttc aagtatttta tcattctttt
    33121 ttttaattct tggagaagaa tcatcagaat aatacctaca atttatctat atgcaaattc
    33181 taaatttaaa ataaagtttc atatgaattt actattctat gctatgatac aacagaaaaa
    33241 actacaatct atgagcggta gcttcatata atcctagttc ctacagtaat caaaaaggaa
    33301 gtttattcta tatgtaacta atgataaatt ctattatagg agttattagc tctatttgtg
    33361 ttactataag tagtaattat atatataata attttttaac acttttctat tggctaaata
    33421 gaaagtagtt tagaacttaa atttaaataa aatttaagtt caccaaaaga aatctatatt
    33481 agaaaccact actctattcc accagattgt aattttttgt tctttatatc ataatgctat
    33541 accacattaa atttaaaaat aaattttaaa tttatttgtt acaattcatt agttcaaaaa
    33601 aatactttga gtcatgagtt ttgtaaagat ttaaccatga atttaatgct tctgattcaa
    33661 aaacctctaa aagtttcaat acttgaaacg taaattccaa cggagcaatt cctggagctg
    33721 taactaaatg ttcatcacta actacagatt ccattttata atatttttct ccagaataat
    33781 ttggtactac cattttaaga aactctaaat cattacttgt atgatttcta aaatctaata
    33841 gacctttttt agctagacct aatgtagctc cacatatggc tgcaactata gaatcttgta
    33901 ttaacgcttc tttagctttt tctaatatta tctcatgatt catagataac caagtatttc
    33961 cccctggtaa aattaataaa tccttacttt ccatattaaa ctcatcaact gtaatttcag
    34021 gtaaaacttt taacccaccc attgttataa taggattttt atcaattcct acagtaatta
    34081 cttttagtgg ttttaatcct tttttaaaat atcttcctgt atttaattca gcagttaaat
    34141 atgccacttc ccaatctgac atagtatcaa atacatacat atatactttt ctatttttca
    34201 tcttttttac tccttatgta attaatttat atatctaatt gtaaaataac ttaactgaca
    34261 tattcagtca gttaagttat taaatttgat aataatcaat taattctagt aaatcttcaa
    34321 tcattttctt cctaaggctt agtggttgaa ttacttgtat tgtctttcta taaggtaaaa
    34381 gtatatttgg tatgtacttg catattactt cctcttcaag cataaatatt attttattag
    34441 gtgttctttc tttcaagtag tgccctaaaa accaatgttg gcttaaacta tctaaagaat
    34501 ctatactccc ttctacaact aattgaatta tactttgttc atcttttatt tcaggtataa
    34561 tcccttttat aaaaaattca cttgccgaaa attctgtcgg tctgttaaat gtatttgatg
    34621 tttctatgat ttcactaatc ctatccactc tgaaactacg aatctcattt ctcatattac
    34681 aaaaggcaac tacataccaa ttattattcc agtgaacaat tccatatgga tttataattc
    34741 tatattttga ttttgcttta cgacctgcat gatagtttat ttctacagat agctccttta
    34801 atatactatt ctccaatttt ttaagtactg attctataga tactttccca attggtttta
    34861 ttacttcaag ggctattaag tggtttgtta aaatatcttc ttgtttttga tttgaataca
    34921 tttttaactt taatatcgat ttatctaatg cttcgtctaa gaagtatcct tcttttttag
    34981 caaatagagc tgcatgaagt agagattttt gctcttctat atcaaaaaaa agaggtgctt
    35041 tagtaaaatt atttaaaagg ctatacccac cattatgacc tatatctgaa attataggta
    35101 ctccactcgc agaaagtaca tcaatatatc gatacactgt tcttatattt atttctaatt
    35161 tttcagctat ctcttttgct gtaatttttt tgtcagagct taacatccac agtatagaca
    35221 tcatattatc aattttagcc atgtagtttc acctctttct atttgttata taaagttatt
    35281 atataacttt tgattgattt tttataaaaa acattagtaa actgctaata atttatacta
    35341 agatttattt caaatattta tagatagtct ttttctatag ttaagttatc cattaaactc
    35401 catagtagta tatctacttc aattaatata ttttcaacta cacttctcgt tatatatcaa
    35461 ttctcttttt taaagagttt acaactgata tttagtttaa gatttatata tattattttt
    35521 caaaaacctt tcaatctcaa attaaaactt ctttgtttta atttgtttaa gatatagaaa
    35581 aaatcttatc ctaatttatt taagctaaaa ttcttatatt ttaaaatttt ctttaaaact
    35641 aaaatattta ttatcatctc cagcaacaat ataatctact aattaaatac ctaatattta
    35701 ttcatatttt catagcttat tagttataac tccatcttct tgctaaaatt aatgttaccc
    35761 aacatataat tgtggaagta attactttag atacatcagt taatacatct cttggatata
    35821 ttagcactga gtttatagcc catctactta caacttctat acttactggt tgccactctg
    35881 tatctaaaca tattactaca aatctttctc tatcactatc tacaaaaagc ttcttactaa
    35941 tctataagca ttataagaat tacttttttt ctagtttcat aaagtactac tttttttgtt
    36001 aatttaaaaa atctatatct actcttttaa aagatgtttt ctttttattc atttacctat
    36061 ttcctatatc tttctgaatt gaaaataata atgtacacta tatcaatgta tattgttata
    36121 taaataaatg ttcagtttct ttatttctag atattcaatt atactacatt cactagataa
    36181 caaatatagt gttgaacttg tatatattta cttcaccttt atatattctc cactaaattt
    36241 tcctaataat ctttttaatc tatttgattt aaaatactct ttaaaaaact ttacttcttt
    36301 cttaccttca actcaactat acacacatat ccactataat ctgttgattt tctgttatat
    36361 ccatagtttt catcaagaac actgacaata ttattcactt tttaagccac tccctttgaa
    36421 tattattaca ataagtttaa atcttctttc ttcaataaat atattatgag gaagactatc
    36481 atctttaatg gtttaatagc gtataaggat atgaatttaa aaaatctatt ttttatatca
    36541 tatgggtatt gttttttata aaactggaaa aacctaatag aatctatgat tttttaacat
    36601 aacctccata aattagtacc aattataact tcaaatttaa attttatcta aagaatatac
    36661 aatcatattt ccagactcaa cataatattg aatgttgcgc ttgtatttac aaattatcat
    36721 tctaataaaa acaattatac atagcttaaa atcatcttct aaacataatt actaaaattg
    36781 aattaatgat atcaattcca ttaatctctt ttaataaaaa attctctttt ctatatgaaa
    36841 attatttcaa aactttaaag ttaaatacaa aaatgactat aaatagattt ttatttacac
    36901 aaatctatct atagccacta tagtttatcc aataaaataa taaaataaat atgtacacaa
    36961 taaatgttat ttacgtctta agtatttatt tattagattt ttaattaaaa aaaacaagct
    37021 agtgaacatt aatgctaaat ctagcattat attgctttga tctcctgttt gtacattttg
    37081 acctgcatta ctatctaaac tttcatctgt atctatattt atatctggtt tcccatcccc
    37141 atctatatct atatttacat ccgatttccc atctccatct atatctatat ttatatccgg
    37201 tttcccatct ccatctatat ctatatttat atctggtttt ccatctccat ctatatctat
    37261 atttatatct ggttttccat ctccatctat atctatattt atatctggtt ttccatcccc
    37321 atctgtatct atatttatat ctggttttcc atctccatct gtatctatat ctatgtctgg
    37381 ttttccatct ccatctatat ctggtttccc atccccatct gtatctatat ctggtttgct
    37441 atttcctccg ttatctgaat ccggtttgct atttcctcca ttacctgaat ccggtttgct
    37501 atttcctcca ttatctggat tcgggttatc tggatctggc ttatttggat ctggattacc
    37561 tgtatcataa cctcccgagt cagtatctac atttttatca ggcttccaat aatcatctac
    37621 tccatcgtta tctgtatcta ttgctggacg attataatct gtatcagggt ttccatctcc
    37681 attggtatct atatttttat caggtttcca aataccatct cgatttccac cttctgtact
    37741 aggcttccat tcacctgtat tatcagtatc tatgttaata tctggcttcc aatcaccact
    37801 tgtatctata ttgatatctg gccttccatc cccatcagtg tctatattta tatccggaat
    37861 accatctcca tctatatcta catttgtaat atctaacttt aacttctttt catctttact
    37921 atctttagtg taatttatat catctccaat atattttaca gtaatagttt gttcagtatt
    37981 aagaatatga tgattactat ctaaaggttt ccattcaata gatgcagtac tataattatg
    38041 actctcacta accttatcat gagtttttaa ctctactgga tctttatatt cctttccatt
    38101 aatatagaat tgtacataac cttttggaga ggcacaatct ggtccttctt tcttatcagg
    38161 tgaaacagta gcatttaatg taaacgtatc tgttggttta aaaacatcag tttttacttt
    38221 aggcgtttct acaactaatg aagtttctgt atcagcagga gtaatttctg cataattata
    38281 atgtgatcta tgcccccaat aagactcatt aaaaggagct acactagcat actgtttcga
    38341 tgtaatgatt aattgatatt ttccaacatc aacttgtttt gtaaggtcat cacttcctaa
    38401 acttgtatct ggttccatcg tttcctcatt taaacgttga gaactaataa ttatatatgt
    38461 tccatctgtg agttttccac ctttaggatt agttactgga ataccatctt ttaatatcca
    38521 atctaaaaat gctttttctt gctcttttcc aaatggtaat ccatcgtatc ttttattaat
    38581 cgaacctggt ggagtattta tctcatcaat aataaattct tcatactgct ttaaaaatgg
    38641 agtagttgga cctatatctt taatataaaa agtatctgat tttagagtat ctccagtatc
    38701 tttatctaca atagctaact taacagatac ttcagatcca gtaaatttat cagagaacca
    38761 taagtaaaga accccttgat catccgtata gctaggcgct ccataaggat actcttttcc
    38821 attaatttgc attgtaaaat catcgactag tttagtatta actttatctt gccctaaata
    38881 ctttagagat actttgctca taaaaacttt tgttttcttt tctaagtcac cgtatgcaac
    38941 tgtttcaccg ctacttttga atgttgttgc ttttaatgaa ccacctgtta ctataacatc
    39001 tcctgttata gcacttaggt caaaaatcca gtctcctgct cctgtcatat aaggtaaaac
    39061 cgttcctcca gttacaagta cacgatatcc tctatttgct cctggattaa cacatccatc
    39121 tccaaatgca ctaccatgtg cccctccata tgaatagcaa agtccaccat taattgtaat
    39181 atttccacta taaccaccac ctttgttacg atctactact gatggactta atgtatgatt
    39241 tcctgatata tagtacgctc cccctattcc agctccatgg tatgcgcctt tagcagttac
    39301 agtaccacca ttgattgtga tatctccacc atcaccgata ctacctcccc ctattccagc
    39361 tccaaatcca gtattatacc cttccatagc tgtagcattt ataataccac cattaatgat
    39421 aatatttcct ccattttcag tatctccacc accaatacct gcagcataag aatttccgac
    39481 agctgttaaa ctccctctgt ttttactatc tagtagtgta aggcgatctc ctttttttag
    39541 cttgtcccca ttttctagag ttacatctct aggaattttc ccattttcag gaactataaa
    39601 ttctccttca atgtctctat ttacaacaga atcatcaata attagagtag tactttttcc
    39661 ggctcttata cctggataaa gttgatcacc tgactttagt atgtttttgc taccatcttg
    39721 taatataata tgtgcatatg caccaccatc tttatctggt gttaaagtaa atgggctatt
    39781 agatgcagtt ttaatattta ctccattaaa tattagttcc gcttttacat ctttaggtat
    39841 aacaatccta tgtgttgttg gagtatttgg attattattt tgaattgtca tttgttttcc
    39901 actaagaata gttaaaacgc cactttcaaa tttaaaatca acatttattt ctccaccgct
    39961 aattttaaag tctcctacag aatcatactc ttctgcatta gtatcttctt ctacaagtac
    40021 ttcattagta tctccttctg catttccttc attagtatct ccttctgcat ttcctgcatt
    40081 agtatctcct tctgcatttc ctacattagt atctccttct gcatttccta cattagtatc
    40141 tccttctgca tttcctgcat tagtatctcc ttctgcattt cctgcattag tatctccttc
    40201 tgcatttcct gcattagtgt ctccttctgc atttcctgca ttagtgtctc cttctgcatt
    40261 tcctgcatta gtatctcctt ctacatttcc tgcattagta tctccttcta catttcctgc
    40321 attagtactt tcttctatag tatctgcgaa agtatttgac acattaaatg atgctactga
    40381 tccaagtccc attgagatac ttaaaatcat tgataatgct ttctttttac atttttgttg
    40441 cataaattcc ccctccccct aataattttt aatatacact gtatacatcc taatatatac
    40501 tctaataatt cttaatatac actgtataca tcctaatata cactctaata ttttttaata
    40561 tatacttaaa acttatattt gtcaatgaat atactgtttt tttcaacctt atatattata
    40621 agtatttatt atttgctaaa taactacaat aaaaatttta aattatataa aatttattta
    40681 atcttttata taataataca tggggtaatt aattgaaaaa actagtaaaa atattaataa
    40741 atattatttg cattattacg ctaattttct ctagcctttc gatttacata aaattatctg
    40801 aatataaaaa ggctgatgaa gtatatactg aactcagaga aaacactagc aataacaata
    40861 gtaaacatca agaactttat gataaaaata atgattatag attctggctt aaaataaaca
    40921 acgcaaatat agactatcct gtagtacaag gatataacaa ggatttctac ctaactcatg
    40981 atttttataa aaattatctt cctgcaggta gtattttcat ggattataga aataactttg
    41041 aaaatgataa gagtttaata gtctatggtc attatatgaa aaataaaact atgtttggtc
    41101 agctagaaag tagaaataaa atataaagga caaacttata cttatgaaat tttttcagta
    41161 tatactgatt acttaattgg cagaaattat ttaagtatac actttaataa taatgatgag
    41221 tttaaagatt ctttgaatta tataaccgaa agatcagtac acaaatctga tataaaggta
    41281 gatatttcag ataaaattat aactttgtat acttgtaact atgaatttaa agatgctcgt
    41341 actatagttc atactaaatt aatttcaaaa aaaagactaa taagtaggtt tgtttaaata
    41401 cagatttacc tacagtcttt aaatcatata aggatctgtt taaaaatggc aactaaaaga
    41461 gctaatggcg aggggtctat tgttaaaaat ataagaaatg gtgttcagat aggatggcgc
    41521 gcttctataa gtattggtcg tgatgagaag gacaaactta taagaaaaca atttactgta
    41581 aaaacacaaa aagagttaaa agaaaaatta gatatttata ggacaaagat gctcttaggc
    41641 tctatagtct cagctgataa aataaccttt gaagattggt tttatacttg gttatttgat
    41701 tatagagcaa aaaatttaaa acctaaatct tttgaaagat atgagggcat ttatagaaat
    41761 cacaaaaaag atactgaact tggaaaaata aaattaatag atttaagagc tacacatata
    41821 caaagatatt acaataaact tattgatgta tataacaaac ctgcatcaac aattataact
    41881 ctaaatacaa gattaaagcc ttgtctaaca gaaacagaaa aacaaggtta tattcaaaaa
    41941 aattattgta aaatgataac actcccatct gataacaaga taaaagaggt acaaatatta
    42001 agtattactg accaaaaaaa atttattgat agcattgatg gagataagtt tgaaatactt
    42061 tttcttcttg ctttgagtgc tggtttaaga ttaggagagt tacttggttt gaaatggagt
    42121 gatattagtt ttgatgatga atctttaact gttagcatga ctttgcaacg agttactgaa
    42181 ataaataaag atggaactag agaaaaaaag tcattgaaca gtatacaaag actaaaaatt
    42241 ctataagaac agttcctatt ccaagaaatg ttttagttaa attaaaaagc ataaaataca
    42301 acaaacagaa caaagattat tgttaggtga tgcttatata aataataatt atgtaatttg
    42361 taatgataca ggtcttgctt taaacaataa tagacctggt aaaattttag attctttact
    42421 aaaaaaatta aatataccta aaattaaatt tcatgctctt agacatacat atgcaacacg
    42481 attattcgag gctggtgtcc ctcctaagac tgttcagaca ttaatgtgtc attatgacta
    42541 tggatatata cacacgttat gcacaatacc aagcaggatg ctgtggataa aataaatgat
    42601 attttttaat gtaaatgaag tgaaattaaa tttattaaca gtaattaaaa tgctataata
    42661 tgtatattat atttagatta agaaaagtca tatatttaaa tacatggctt ttcttaatat
    42721 tatttgtcta caatatgaca gtccttttat tttgatgaat ctagtatctc accaaataat
    42781 tttctatact cttctgataa agatacattt acaagttcac accatatatg ctcttgaata
    42841 tctatatttt caatacacca tactttataa tggcactcct tagttatata aaaatcaatt
    42901 ttaatttcat tggtagaatt atcttcttgc ttggaacagt attctttaaa tggatactgg
    42961 ttttttataa aatctatatg tctaaatgct tttcttttag gataatattt accatgaata
    43021 aaagttgtta taatatcttt atttgattta aaccctctgt ctatatatgg aagttctttt
    43081 atttcaatat gccaaaactc ttcatcaaga atatcatcat atctcttttt tataaccata
    43141 agtagtttat tataattatc attatctcca tgaacaataa tatttttcaa cttttctagc
    43201 ttagtattag aaaaatcaaa tgtacatcct cgccattttt ggaattttaa aatagtacta
    43261 acatatgcat acttcaatgg tactgcaaga cgttcatcta atcttaaata aaaatttgat
    43321 ttattaaaat ctatattttg ggacataatt tcaaaaactg caggtataag actatttata
    43381 tttatttaaa ggagatttat caataaaaat gttatataag taatattttt tatcatatat
    43441 aaaaccattt tgtttaaagt ccaagttttc tattttagta agtttataat catttatatc
    43501 atacatatgt ttttcatatg aaattactga cttaatattt aaatcatcat atctaaatct
    43561 atccaacaca aaacatgtaa caacacaaaa caatagatct tcatcaatgg taatattagt
    43621 tggaaattct ttttccccac atgaaatact atatatatct gaatatgcca catccctagg
    43681 aaatgtatag gaaagtattt actgtgctac aaaaaaataa tgtgttcttt tcttggggtc
    43741 agtaatatat tgaaatattt ccgattgagt taaatttctt tctttaatta gagatttaac
    43801 ttcattacaa agttgtttaa tataataagg aacaccactc caattcctca ccttaagaga
    43861 tttccataaa ggctcatcta aatgaaaagt ataataactt gtattatagt aactatctaa
    43921 atttttgata tcttgtatca atttttccat tattgttatc cccctaaaaa ttttagtcta
    43981 attgtattga tttacataag cttctagttg tgcgctaatt gtgtgtcttt caataatgca
    44041 aaagggatta ctcagtctaa atccaagtaa tcccaatcat ttcatcattc ttttttcaaa
    44101 attggtggag acgaatcgtc agaataatac ccacgattaa ttttgttatt atatattaat
    44161 actactactc attaactaaa atttgaatta aatcaaatac taatttgaaa ttttcaaaag
    44221 atatattctt gaactcctct actccattta atatactatc tgcaaaatca ttcttgctta
    44281 gtgcaatatt atcctcagga ttcttaatat cacatactac acaccccgaa tctataatag
    44341 acttctttcc acatttattt ttatcttgac atattttatc ccctaatata tgtaatccta
    44401 gtttagaatt aaattcatcg cctaaaaata atcttctacc tttgtagaat gtttttattt
    44461 cttcatcaga ataataatgt tctatacaca ttattttatc aatttcaacc ctgttatccg
    44521 gcaatggcaa taccattgat attacattat taccccataa tttataattt gtattttcat
    44581 cttttacttt tcttagatcc ctatcactca agtctctatc aaaaacacat attaccttat
    44641 tattgttcct taatttactt gccgcttcac aaatatttat taaattatta tagcccattt
    44701 ttatatcatt ttcatactct aaaaattcaa tatctaaatc atgatataat ccttgctctt
    44761 ttaattttaa taaaccagct ttcatatgtt tccaatctgt ctttccttct gtaattatta
    44821 atgtctttcc atttttactt tttaatatat cttgtatatc ttttgaaaat aattcagtcc
    44881 tcttataata ttcatatgat ctttcaaatt ccgaaaactc ttccggtcca atgttctctc
    44941 ctgttggcat ttcatatatc ttaaatccat cctctttaaa tatatctttc atacctaata
    45001 taaataatgg agaatgagat gttattataa attgaacctt tggaaacttt tttattagtt
    45061 ttggtagtac gtcgcattgt atactcgaat gtagatgtaa atcaatttca tctattataa
    45121 caataccttc tatttcattt aattttatac tcttattaat atctccataa tctgaatatc
    45181 taattattgt tgaaaacatg ttaaataatg ctgactctcc tgtagataaa gcatctaatg
    45241 taggtataat cattgaattg gtcgacctat caattatatt aaatctggat ccacctgaat
    45301 ttctccaatt taatccaaac ttaacatcct tctttactat ttcagataat atttcttcca
    45361 cattttctct tgctattttt agtaatctta tattatttaa gtcttgttcc gaattccatc
    45421 cacctaggtc actctgtatt aaatcagctc tagaatctac aattatatct aaaagccatt
    45481 taatattagt ttcagttaca ttttgtacga ttatgggttt atttaattta ccagatattt
    45541 tatcatttat tgttataaga ttttctgaga tgatattttg attcatccag tgaggtgttt
    45601 catatctatt cggaggaaaa aaacaaaaag atttatttgc aaattcttcc tcaaaatact
    45661 ctttattttt agttatatct tttatatttt ttctattacc ccagttatta tctaaattta
    45721 atagtccact agtcttttct atgcattgct caaatgataa gttccctaat ttttctatat
    45781 attgaaaatt ttgttctcca tttacaaagt tgataaatga aaaagaataa tcacatccaa
    45841 cctttgtgtt tttccaagat aaaactttaa aataaggtgt tgtaccatct ttatttgttt
    45901 ctgttatatc attgtacggc tgttttgcaa attcaaataa tgaatcaact atgttgctta
    45961 atacagttga tttacccttt ccattttcac ctacaaatat aattggtttt ggacttccat
    46021 cttcattgaa tggaaaccct atatctaagt tatctatagg tcctacattc tccattatta
    46081 ttctgtctaa aaacatttac tatcttcccc tttatatatt tatattaaaa aagtattgat
    46141 atttatatca atacttttcg tggatttcaa tggtggagac gaggggagtc gaacccctgt
    46201 ccgcaaatct tttccttgct gcatctacat gcttagccaa cttcactaat atctcacctc
    46261 acatagcgcc aagtggcagg ctctatgctt agccagtccc aattaatcta ctttaagtcg
    46321 agacacccct aaagtagttc cctgcataat gacgtccagt cttagtcggc aggaggacta
    46381 agagggacga gcagcaacta ggctgctatc gcgaaattat cgtctgcgtt tattttaaag
    46441 ttccccagtt tttacgtgac ccagagtaac acgacatgca gcctcaagtt ccaaacccac
    46501 gtcgaaacct ttacgccccc ttgagtaatt tatagtccag tagactcttc gcaaacttta
    46561 tcaccatttt tattaaattt ttaatgtata tataatataa tacttttaag aataaaaatc
    46621 aatgttatgt tctagataat aaagaatttt attctaaaaa atacagtttt atctagttta
    46681 atacttcccc gtcatttctc tttctatacg tctttgtgca tctttcttag ccatatcttg
    46741 acgtttatca tatagttttt taccttttgc taatgcaatc tctactttaa ccttaccatt
    46801 ttttagatac aaactcagtg gtataagtga ataccccttt atagtagttg ctccaataag
    46861 ttttcttatt tcatgcttat gaagcaataa ttttcttact cttaaagaat caacattgaa
    46921 tatatttcct tgctcatatg gacttatatg aacttgtttt aaaaatactt cactattatc
    46981 tacagatgca aatccatcac ttaagttaac tttaccttgt cttattgatt ttacttctgt
    47041 cccttttaat tcgattccac attcataggt ttcttctata aaatattcat gtcttgctct
    47101 tttgtttgtt gctaatattt ttttaccagc catataaatc tcaccttctt tgctagaaat
    47161 ttcttcaata aatattagaa atttgctaaa tatttattgt caccaaatta tttgactaac
    47221 ttgtatgata acatatttag gcattttagt caatatttca ctgatatatt aagttattta
    47281 ggttatatat aataaacaat ataaatatat aaaaataatt aaaaaactat ttgaaatata
    47341 cttaatatta aactacattt aaccagtaac actactttat aaacttcaaa acaaaaatat
    47401 tacatattat aaattttcta t
//
LOCUS       DAMKOJ010000025        45421 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000025 DAMKOJ010000000
VERSION     DAMKOJ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45421
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.026"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            252..596
                     /locus_tag="PC592_001508"
     CDS             252..596
                     /locus_tag="PC592_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055491.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIEKFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            complement(927..2303)
                     /locus_tag="PC592_001509"
     CDS             complement(927..2303)
                     /locus_tag="PC592_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF4055492.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGHSIQSIIPNTKMLDVMRDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENKDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(2402..3424)
                     /locus_tag="PC592_001510"
     CDS             complement(2402..3424)
                     /locus_tag="PC592_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF4055493.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSMCDYGIVGDLYEIIPEM
                     IESLNR"
     gene            complement(3435..4229)
                     /locus_tag="PC592_001511"
     CDS             complement(3435..4229)
                     /locus_tag="PC592_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF4055494.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKINVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            complement(4240..5382)
                     /locus_tag="PC592_001512"
     CDS             complement(4240..5382)
                     /locus_tag="PC592_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF4055495.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASHTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            complement(5422..6654)
                     /locus_tag="PC592_001513"
     CDS             complement(5422..6654)
                     /locus_tag="PC592_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF4055496.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSKAGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            complement(6791..8131)
                     /locus_tag="PC592_001514"
     CDS             complement(6791..8131)
                     /locus_tag="PC592_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF4055497.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFVVGSTILYKMVSKEKANGGHFIA
                     HESDVFDESEATNSKKENGPNGVIALIPLIISILIINVKINGQAIVPIEVGVFIGALL
                     VYLLLNKYQDNAKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            complement(8225..9019)
                     /locus_tag="PC592_001515"
     CDS             complement(8225..9019)
                     /locus_tag="PC592_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF4055498.1"
                     /translation="MESIMENLNNLKVEVKDKVCVITINRPKALNALNNDTLRELSQV
                     IDVISENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESIKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKSALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            complement(9763..10482)
                     /locus_tag="PC592_001516"
     CDS             complement(9763..10482)
                     /locus_tag="PC592_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF4055499.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKDGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(10565..11320)
                     /gene="nadE"
                     /locus_tag="PC592_001517"
     CDS             complement(10565..11320)
                     /gene="nadE"
                     /locus_tag="PC592_001517"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF4055500.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPSQPPKF"
     gene            11498..11884
                     /locus_tag="PC592_001518"
     CDS             11498..11884
                     /locus_tag="PC592_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF4055501.1"
                     /translation="MKKTDGLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTTSSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            11884..12261
                     /locus_tag="PC592_001519"
     CDS             11884..12261
                     /locus_tag="PC592_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF4055502.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGVF
                     LLLVGLFEVKKGFCAKSNKKPLN"
     gene            complement(12347..12991)
                     /locus_tag="PC592_001520"
     CDS             complement(12347..12991)
                     /locus_tag="PC592_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF4055503.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVVVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLESGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTIYEDNVEIVVYSRLEDVDKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILL"
     gene            complement(13300..13743)
                     /locus_tag="PC592_001521"
     CDS             complement(13300..13743)
                     /locus_tag="PC592_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF4055504.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVFAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            complement(13830..14507)
                     /locus_tag="PC592_001522"
     CDS             complement(13830..14507)
                     /locus_tag="PC592_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF4055505.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDESSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            complement(14515..15798)
                     /gene="hflX"
                     /locus_tag="PC592_001523"
     CDS             complement(14515..15798)
                     /gene="hflX"
                     /locus_tag="PC592_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF4055506.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTSESMEELKELTKAAGAE
                     VVGSLIQNKHSIDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGENGITLDVDLDEEDFNIYREYILEK"
     gene            16015..16275
                     /locus_tag="PC592_001524"
     CDS             16015..16275
                     /locus_tag="PC592_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF4055507.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCMLPHKKDNYNYIMGKFQDLVKITSKK"
     gene            complement(16381..17016)
                     /locus_tag="PC592_001525"
     CDS             complement(16381..17016)
                     /locus_tag="PC592_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDF4055508.1"
                     /translation="MKKFLNVLFSVCISIVIIVGVINFTVGFKKLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFNLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLIVSLVGIILSVKNKNIKILKTTSITLIMMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPNLDPVINILPEEFFFHSGMMILILILLSSILLFVMYKLCKYFKIK"
     gene            complement(17044..18594)
                     /locus_tag="PC592_001526"
     CDS             complement(17044..18594)
                     /locus_tag="PC592_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF4055509.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQDYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            complement(18796..19680)
                     /locus_tag="PC592_001527"
     CDS             complement(18796..19680)
                     /locus_tag="PC592_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4055510.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKGENSNKNNKDKEEDKSNSKSNKDKLSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKNILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIIQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDEYFK"
     gene            19908..20915
                     /locus_tag="PC592_001528"
     CDS             19908..20915
                     /locus_tag="PC592_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF4055511.1"
                     /translation="MQLKNFHFKDNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNECKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLTQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            complement(21127..21825)
                     /gene="yunB"
                     /locus_tag="PC592_001529"
     CDS             complement(21127..21825)
                     /gene="yunB"
                     /locus_tag="PC592_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF4055512.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            22040..24733
                     /locus_tag="PC592_001530"
     CDS             22040..24733
                     /locus_tag="PC592_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF4055513.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWDLISSDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLDLKYIKQSEYDEAIKAKIEIKLPKSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDKNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQST
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKKAPEEHKVVDPEVAYVVTDMLESVITEGTGGVAALPN
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKVMQKIHANLTVTEFEVPKNVYFTKINLDDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQQQENNNNNNNSGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNSGGGSTNTPDGGGTPAT"
     gene            complement(25359..26294)
                     /locus_tag="PC592_001531"
     CDS             complement(25359..26294)
                     /locus_tag="PC592_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HDF4055514.1"
                     /translation="MILKQVIEVYDILDKADANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKSKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(26338..27510)
                     /locus_tag="PC592_001532"
     CDS             complement(26338..27510)
                     /locus_tag="PC592_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF4055515.1"
                     /translation="MECFKEVVNMNELKVKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFSGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTSVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            complement(27497..27961)
                     /locus_tag="PC592_001533"
     CDS             complement(27497..27961)
                     /locus_tag="PC592_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055516.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLKLNGML"
     gene            complement(27976..28818)
                     /locus_tag="PC592_001534"
     CDS             complement(27976..28818)
                     /locus_tag="PC592_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF4055517.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTART
                     SNKL"
     gene            complement(29192..30208)
                     /locus_tag="PC592_001535"
     CDS             complement(29192..30208)
                     /locus_tag="PC592_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF4055518.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAMFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            complement(30392..30754)
                     /gene="spoVAE"
                     /locus_tag="PC592_001536"
     CDS             complement(30392..30754)
                     /gene="spoVAE"
                     /locus_tag="PC592_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HDF4055519.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            complement(30767..31780)
                     /gene="spoVAD"
                     /locus_tag="PC592_001537"
     CDS             complement(30767..31780)
                     /gene="spoVAD"
                     /locus_tag="PC592_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HDF4055520.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLTDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGEGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGIDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            complement(31934..32371)
                     /gene="spoVAC"
                     /locus_tag="PC592_001538"
     CDS             complement(31934..32371)
                     /gene="spoVAC"
                     /locus_tag="PC592_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HDF4055521.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            complement(32658..33422)
                     /gene="sigF"
                     /locus_tag="PC592_001539"
     CDS             complement(32658..33422)
                     /gene="sigF"
                     /locus_tag="PC592_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HDF4055522.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            complement(33445..33873)
                     /locus_tag="PC592_001540"
     CDS             complement(33445..33873)
                     /locus_tag="PC592_001540"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HDF4055523.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            complement(33887..34222)
                     /gene="spoIIAA"
                     /locus_tag="PC592_001541"
     CDS             complement(33887..34222)
                     /gene="spoIIAA"
                     /locus_tag="PC592_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HDF4055524.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            complement(34309..36417)
                     /locus_tag="PC592_001542"
     CDS             complement(34309..36417)
                     /locus_tag="PC592_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF4055525.1"
                     /translation="MDITKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDEVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGSPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYIQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKRYLYSLELSFLIDECGVKENDIREL
                     VALYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSKLYGQDREFYVSNISKFIEESLRNTSNKINNVSDEPDTKSNKTDYISNDLY
                     SLSGKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCFDMFMTDTATLCD
                     LFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFMELAKKMRLNDYPF
                     VEKSTYLEKVIEPLKCVDKNLDIEKLKNNYFTIHNPVAWEDKKFETPSGKYELYSESI
                     KNLGINPTPVYINNKYKEIEDKNENISFRLLTNHHADTLFSQHFMDKKSIAQAYINQR
                     MAKKVGIKDKDTVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHGNPNILTDTGI
                     SDFGGQVTYNESIVEIIRQN"
     gene            complement(36765..37538)
                     /gene="srlD"
                     /locus_tag="PC592_001543"
     CDS             complement(36765..37538)
                     /gene="srlD"
                     /locus_tag="PC592_001543"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDF4055526.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAK
                     EIEMEFGCKSVGYGCNAIDEIQVMSTIKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFMDVANILTFYASKEAEYCTGQSINITGGQVM"
     gene            complement(37638..38003)
                     /locus_tag="PC592_001544"
     CDS             complement(37638..38003)
                     /locus_tag="PC592_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF4055527.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTNDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            complement(38044..39003)
                     /locus_tag="PC592_001545"
                     /pseudo
     CDS             complement(38044..39003)
                     /locus_tag="PC592_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003443125.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
     gene            complement(39067..39627)
                     /gene="srlA"
                     /locus_tag="PC592_001546"
     CDS             complement(39067..39627)
                     /gene="srlA"
                     /locus_tag="PC592_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF4055528.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            complement(39656..40090)
                     /locus_tag="PC592_001547"
     CDS             complement(39656..40090)
                     /locus_tag="PC592_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDF4055529.1"
                     /translation="MDPVIFIIVSFIVVYLLNIFLGYLQIKDFNKNYIELKRKGRVAI
                     GRKKGRISSGAIVLILINDDGVIIETRKMQGVTVVARVKSFEGLVGKNLKYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDMSNLSTDEECRMEVV"
     gene            complement(40095..42080)
                     /locus_tag="PC592_001548"
     CDS             complement(40095..42080)
                     /locus_tag="PC592_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4055530.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSSVLGVSTRTIRNYIN
                     QINRELKDGIAKIVKNEKGTYSIRVEDESKLIEIVNFNRVKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLVLDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIISALRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIEDAILLKNSINIKSIK
                     KIEKNIPFIGKLIEEDKFFILNKGTFMENLEEMLEKLVLKGIIDIEFKENVLKREKKS
                     STALDNYIALPHSVSPNEENLYLAFGILENPVIWDTKEIRIIILMIIPDKNVGSTELI
                     IKSYEEVLEIGRDKKIVEKLSKVKSFDEFYKIITTRR"
     gene            complement(42487..44100)
                     /locus_tag="PC592_001549"
     CDS             complement(42487..44100)
                     /locus_tag="PC592_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF4055531.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLENFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            complement(44191..45252)
                     /locus_tag="PC592_001550"
     CDS             complement(44191..45252)
                     /locus_tag="PC592_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDF4055532.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDILFITVVLFLVGFLLITKGADIF
                     INCTVEIGRKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFLSPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKSRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVRIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAISAIPNNIPILSQNRQLDIPFMILLILIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
BASE COUNT        14559 a         8270 c         5149 g        17443 t
ORIGIN      
        1 aaacatcttt atttatatat cacttatatt tggatatatt ttcttttttt agttttcggg
       61 ttagtaaggg gttagtagtt taggttttca caggatatta tttttacaat tagttttatt
      121 tttgtataat atatatatgt tgcaattaat aaaactaaat atgatttaaa taattcctta
      181 ggataaattt aataaaactt agattcctta tctaagctta aaatactaaa attattggga
      241 ggatataaat aatggaccaa atcaaacgtt tacatgaatt gcaacaaaaa tcatatttga
      301 ctaaagaaga atttgaggaa ttaaaaaata acacatatat tgaaaaattt gaattaagag
      361 atgagtgcga taactcttat atttacacat tttacactaa cgacaaatgt aatgatataa
      421 aatttataaa gtcacaattt atcgttacac ttataaaaat tggtttccta tgtgagtgtg
      481 gtggtgtatt tagacagaag aaaatagttg atgaatatga ttacggatat aatgctatat
      541 ataagtgtga ttcttgtgga aaggaacttg ataaagaagt agaaaattat gattaaataa
      601 caaaaaagtt attcaaaata tttttataaa tgctagataa aattcactct aaatttgacc
      661 taaactatcc ctcttagtag acagttaaaa tatgaaaact gtccaaaact aagagggttt
      721 tattctgtcc taaattaaac ataataatct tagacatcaa aagataatga aatatagata
      781 gtaattataa atacaataaa aaagtactaa tgattgacac tagtacttca caactacttt
      841 tgcacatttt aactacctaa aacagtttat acagttcacc ttgtataatg ttgattcttt
      901 tgcacattgc tttaattcaa gtcatcttaa ttatttaatt caatttcata cttttttatt
      961 ttcttatata aaagactctt gtgtattccc ataacctctg ctgccttaga acatttccaa
     1021 ttgtacttcc ttaacacatc aataattaaa ctcttttcat aattctcaac catttcatga
     1081 attgaacagt tactatccac attacattga gctactctac tgatattatc cattttagat
     1141 ggaaggtcac acatcataat gaccatatca tcacttacag cataggcact ttttattaca
     1201 ttttgtagtt ctcttatatt tcctggccaa gtataattaa taaaacaatt tttaacctta
     1261 tcacttagaa ccttcaattc cttgtattca acatttaatt tgtttaatat ataatttgct
     1321 aacaataaaa tatcatcttg cctgtccttc aattccatca tatgaatgtt tattacattt
     1381 aatctatagt ataggtcttc tctaaataat ccttcttcaa ccattttact tagattcttt
     1441 cttgtagcag agattactct tacatctatc tttatggttt taagacctcc tactggttct
     1501 atctcacttt cctgaagaac tcttaaaagt tttgcttgca tagtcaaagg catgtcacct
     1561 atttcatcta aaaagattgt accattattc gcaactaaaa acttgccttt tttaccacct
     1621 ttttttgctc ctgtaaaagc tccttcatca taaccaaata actctgattc taataattct
     1681 tctggtattg cagcacagtt tatactaacc ataggtttgt ctgacctact gctattattg
     1741 tgaattgctc tagcaaatac ttctttccct gtgcctgttt cacctgttaa aagtactgga
     1801 aagtttgttt tagaagcttt cacacctgtt ttcttaagtt ctataaaatc tttattttca
     1861 cctatgagct tgtcaaaacc acaattatcc ttaaactgtt ctttataata ttgaagctcc
     1921 atatattctg acattaactt tttagccaca tcaaaggatt gcaatctaaa tttaacttga
     1981 gctactcctg caactacttc tccattgtca ttttccacat aagacctact tactatcaca
     2041 cttttttctt ttgtatttcc acctgaataa tgatgtatag ctccttcttc acagtactta
     2101 tctctcataa cgtctaacat ttttgtattt ggtataatac tttgtatact gtgtcctatt
     2161 atatcttttc tttcttttcc taaaaagtca caatatttat cattaatatc tattattact
     2221 ccacttgtat ttacaacaat aaaaccatca tcagtcatag ataatactct tgcaaatata
     2281 tccttatacc actgttcttt cattgtttca tctccccact ataaccttca gcaaaaataa
     2341 taagtcttac aatacaatat tataagactt atcattctac atattcaatg ttttctagaa
     2401 gttacctatt taatgattct atcatttcag gtataatttc atataaatct cctactattc
     2461 catagtcaca catactaaaa ataggggctt ttgcatcttt atttatagca actatatatt
     2521 tagaatcact catacctgct aaatgttgta ttgctccaga tattccacat gcaatgtata
     2581 gttctggtct aacagtagtt cctgtttgtc ccacttgatg agaatgttct atccaccctg
     2641 aatctactgc tgctcttgaa gcaccaatct ctgcccccaa tttatcagcc aattctttta
     2701 taagctcaaa tccttctgct ctttttaatc ctcttcctcc tgatactatt attctagcat
     2761 cagttagatt tacagatttc ttttcttgtg gaagtatctc tactaatcta gttctaatca
     2821 ttttttcagt aagttctgga gtaacaactt ctaaaattcc agtctctgat tcatttctta
     2881 cagcttttgc cataactcct gggcgaactg ttgacatctg tggtctattt ttaggacaaa
     2941 caatagtggc cattaaattt ccaccaaatg ctggtcttgt ttgtaataac ttattatctg
     3001 ttgaatctat ttcaagtttt gtacagtcag cagttagacc tgttccaact ttacctgcaa
     3061 ttctaggcgc tatatctctt cctatagaag tagctccaac taatacaacc tctggctttt
     3121 ttctttcgat taagtttgca attgaaattg catatccatc agtagtgaaa tctttaagaa
     3181 gagggtcatt gatataatat actttatcaa cactatagtg aagtaattcc ttcacctctt
     3241 tctctacttc atatccagct atcacaactg caagctcttt tcctaattgg tcagcaagct
     3301 ttcttccttc accaataagt tctatagtaa caggattaat tttgccttct ctttgctctc
     3361 ctattaccca aacaccatta taatcattta aatttatacc ttgattaact tttgctctca
     3421 tcatcttaac actcctatac tagtttcaaa tcgaatagta tttctattag tttctcagct
     3481 ttttcttttt tatttatacc ttctattatt tcattatgct tgtctttaac tggtacaaaa
     3541 gacttataaa catttgtagg tgaacccttt aatccaattt gagttgtgtc aacatctaaa
     3601 tctgcaagtg ttaacacatt aatctttgca tctccattat tataagcttc taagattcct
     3661 ttgacacttg gatatcttgg attatttaac tcttttatag cagttagtaa aactggcatc
     3721 tttgcttcga ttaaataatc tcctgtctct gtataacgag ttactagtaa tttgtcatct
     3781 tgaactttta cttcttttgc ataagtaact tgtggtattc ctaaaaattc tgcaacctct
     3841 ggtccaacct gagctgtatc tccatctata gcttgtcttc cgcagaatat tacatcatac
     3901 ttcccaacct tctctatagc agcagcaata attgtagatg tagcccaagt atctgagcca
     3961 ccaaaagctc tatctgaaat taaatatgct tcatcagcac ccattgccaa agcttctttt
     4021 aaagcacttt tagcttgagg aggtcccatg cttataacct taatcactgc tcctaattca
     4081 tctttcattt ttaaagcttc ttctaaggca tttctatcat ctggattgat tatacttggt
     4141 acaccatctc ttattagagt acctgtctct ttatttattt taacttcatt agtatctgga
     4201 acttgcttta agcaaacaac tatattcatt ctcttcctcc tatcctagta ctgctcttga
     4261 aataacaact ttgtgtattt ctgaagtacc ttcgtaaatt tctgttattt tggcgtctct
     4321 gtacattctc tctaatggat aatccttcat atatccatat cccccatgga tttgaagagc
     4381 tagatttgta acctctcttg cagtatgtga tgcattgtat tttgccatgg cagcttcttt
     4441 agtgtgtttt tctcctctag ctttcaagtc tgcagcataa tatactaaca attttgctga
     4501 ttccaccatt gtcgccatat ctgctatata ccattgaata ccttgcaagg ctgaaatcgg
     4561 cttgccaaac tgaactcttt ctttagaata tttgatactt tcttctaagg ctccttcagc
     4621 aattcccaca gcttgagctc caactccaat tcttgctcca tctaaacagg tcatagctat
     4681 gttaaatcct ttgccttctt ttcctaataa gttagacttt ggaactctac agttatcaaa
     4741 tattaactct gcagtttctg aaccatgaat acccattttt tcttcaattt ttcctattga
     4801 aaaacctgga gtccctttgt caacaatgat agcagacatt ccctttattc cctttgatgg
     4861 gtctgtcagt gcaaatatta ttaatgattc tgcttgacct ccaccagaaa taaaacactt
     4921 agttccattt aaaacatact catcagtttc ttcatcaata attgcagttg ttgcagctct
     4981 tgcagcatct gaaccagcat taggttcagt taaagcaaaa gcacctacac acccaccttc
     5041 agccatcatt ggaaggtatt ttttcttttg ttcctcagta ccaaatttca aaatagcttg
     5101 agcatatatt gtgtgtattg ataatattgc tgcagatgct gcacattttt tggcaatctc
     5161 agtaacaaca attacctttt ctatatctgc tccaccagaa ccactatact ctacaggtgt
     5221 tccaatacca ttaaatccta ttttagccat tttgctaaaa agctcccttg gaaaaatacc
     5281 tgttttatct gtttcagcag ctattggtgc tatttcattc tctgcaaatt cttttgctac
     5341 tctttgaagc attaattgtg cttctgttaa tctaaaatcc ataaaattcc ctcctattta
     5401 ttaacatact ccgcatgttt attaacatat ttcacatgct tctttattca ttgttacaat
     5461 tccagattca attagagctt ctatatcaga atcactgtat ccaagttctc tcaatatctc
     5521 atctgaatgt tctcctataa gtggagcatc acaagtcatg ttaacttcaa tatttccaaa
     5581 tttaactgga gtagatgcaa gcattgtctt atttccattt ttacttgtat gctcatatat
     5641 gtaattatta gcaatagcct gttcatcagt tactacatca ttaacatgtt gaattttttc
     5701 atgggctata tcagcagcag taagcttttc aaccatctca ttttgagtaa actttgcaaa
     5761 ttcgccatcc aaaatattaa taagttctgt agcatttttc ttactctcta ctgaagaagc
     5821 aaatttctct tcttttatta agtcttctct accaaataat ctacaaagtg cctcaaaata
     5881 tctttcatgc tctaaaatac ttaagaatat ccactttcca tccttacaac gataagaatt
     5941 tattactgga gaaatagcat tttttctagt ttttggatac tcatcgctaa actgtgtaga
     6001 tgctaataaa gatgatgcat tccatattgc ttgtccaaat aaagatgcca ttactttttg
     6061 tccttttcca gtcttagctt gctggtacaa agctgcacat attcctccag ataaactaca
     6121 agacgttgtt gcatctccaa aagctatagg tggatttatt gggcttgtat ctttttctgc
     6181 tatatcaagc atagctccac ttcttgccca aaaggcaact gtatcaaatc ctgcattatc
     6241 tttagcaggt ccaaagtcgc caaaaccatt tatctgaccc cagataaggt gtggatgctt
     6301 tttacttaat gattcatagt caagacctag tctttttaat gctccggttc tataacttga
     6361 aacaaatacg tttgcttcac ttaaaagttt atccataatt tcaattccag ctttgctctt
     6421 aagatttata gatagacctc ttttatttga attatatgta ctgtaaaaag gattattata
     6481 atcatctatt ggcattgtca ttgttgctcc tgtctttctt cctgggtctc caaagcttgg
     6541 ctctacctta ataacatcag ctccccagtc agctaatatt ttagaagttc ctggacctgc
     6601 tacaaaatac gttaagtcaa taaccttaac tccttctaat ggtttattta acactttcaa
     6661 ttcctcctta tatggtcatt ttgttatttt aaatacaaac ttacagtatt aaaacatgaa
     6721 atttattgta tatactttga aaattaattt tacaatatca aaatataatt tatgcatttt
     6781 atcttctttc ttatggtaat cctgggaaca ttgtaaacag taagactgct actatggttc
     6841 caataaacgg agttaaaaca gttacccaga atattggcat ataggcatcc ttatgtgttt
     6901 ctttacacag accatttgtt acagtaacga tatatccatt gtgtggaagt gaatctaatg
     6961 ctgctgatga aattgccata gtcctagtta atgctgcagc agaaacaccc ttagctaaaa
     7021 atactggtcc aagaagtgga gctgcaattc ctagtccacc tgaagctgac ccacagatac
     7081 ctgcaataac tgtagttcca actgcagcgc ctgcaatagg aggaccagga atattagtca
     7141 tggcattaac tatgaagtca aaaccaactg ctgattttac tactgaacca aatgcaacta
     7201 cagcgcaagt attacatatt gctactactg tagttttaca tgcatcacca acatgtccaa
     7261 ctattttagc attatcttga tatttattta acaataagta cactaataaa gctccaataa
     7321 atactcctac ctcaattggt actattgctt gtccattaat ttttacatta attattaaaa
     7381 ttgatattat taatggaatt aacgcaatta caccattagg accattttct ttcttagaat
     7441 tagttgcttc tgattcatca aatacatctg attcatgtgc tataaaatga ccaccattgg
     7501 ccttttcttt tgaaaccatt ttgtacaaaa tagtgcttcc aactacaaac attactgcac
     7561 atgatataaa accatttact gctccagcca taatatctgt ccccaatgtc gaggctggga
     7621 caatattttg aatttgtggt gcgcctggtg caaccatagc aaaagttgaa catccaaaag
     7681 tcaacgctgc tggtataaat cttcgtggca aatcagcttc tttaaaaatt tctaaagcta
     7741 tcggaaacac tgcaaaactt acaacgaaaa cacttactcc accataggct aagattccac
     7801 aagctattgg aatagaaagt aatgctttat ccttcccaat ccaccttaca atcatcttag
     7861 caatagactt tgctccacca gtaatctcca ttatttttcc cattaatgta cctgttagga
     7921 aaataaagaa attcgcctga agaaatccaa caaaccctgt catataatcc accttaagcg
     7981 catcatacac atttagactt cctgttatag caactaatga tgaacataca attgctatta
     8041 taaaaatatt gattcccttc ataaccatta caactagaag agatagagct atgataatcc
     8101 ctactaaact tataattact cccgtattca taaattaact ccttttaaaa ttaaactata
     8161 tgtatttttt cacgaaattt agattttgaa tatattctac attgttccaa tttagttgta
     8221 atagctactt attttcaaaa actggctttc tcttttctat aaatgcattc attccttctt
     8281 gcttatctct tgtagcaaaa gttaaacctg caatatcttt ctctagttca agagcactct
     8341 ttaaatccat atctatcccc ttgttaataa caacttttgc atatcttatt gctattggcg
     8401 ctttttcaac tatttgattc atcatcttta tagactcttc taaaagtaaa tcacttggaa
     8461 ccactttatt tataagccca atagatttag cttcttctgc atttacttgt ctccccgtaa
     8521 aaattaactc tttggctatt ccagttccaa caagtcttga taatctttga gttccaccaa
     8581 aacatggaat aactcctaaa ttaacttcag gttgtccaaa tatagccttt tctgatgcaa
     8641 ttctaatatc acaactcata gcaagttcac atccaccacc taatgcatat ccattaactg
     8701 ctgctattac tgtcttctca agagcttcaa ttttatcaaa aattccctga gcataacctg
     8761 catattttct gccttcctca cttttatagt tttgcatctg acgtatatca gccccagcta
     8821 caaaaacttt accttctcca gtaataatga ctcctaatat tgcctcattt tctgatatta
     8881 catcaataac ttgtgatagt tccctaaggg tgtcattatt aagagcattt aaagctttgg
     8941 gtctatttat agtaataaca cagactttgt ccttaacctc caccttaaga ttgttcaaat
     9001 tttccattat agattccatc atattccccc cattatacat tgttattttt tctacatttc
     9061 ttgttaatat aaaatagcaa gtactatgcc aatcaccagt gaagctcttt atttttaata
     9121 aaataaacga aatatacata aatttcacta aatttttaat aatttttaac tttaaaattg
     9181 attaaattgt aattcaaaaa agaatttttc ttcaataaaa ctcataaaac aatatttttg
     9241 tctcattttc gagaaaatac ctaaaaaaca cagtctcatt tttgagaatg cagtctcatt
     9301 tttgatattt ctattaaaat attttaagca gtatatctat aagtttactt cactctaata
     9361 taaggaatct ttattcaaca tagtagataa tttattttct attgacttaa atcattaata
     9421 ctttagttca atatatatct attctaatag tacaaattta tcaataaaaa taggaaaaac
     9481 cacaaagact taatgtctaa gtaacttttc ccatcttaaa cgtttctgac aattttagat
     9541 ttgatttgca atgttaagtt aatctcattt gatattattc taaatcaaat aactccgttt
     9601 tcttttaaat ttcttaacct ataaatataa aaacacctct tacctattat gcaaatatag
     9661 gttagaggtg tatatgttta ttttagtaat ttaatatgtt ataaaattta tcacatatta
     9721 aaattaatgc aatacttata aacttcaata tacttatact atctattcta cttcccagtt
     9781 atgatatata tcttgaacat catcatcttc ttcaagcata tcaactaatt tattcatcat
     9841 ttttaaatga gattcttcag tcaatacagt cgtagtttga ggtatcatct tcacatcagc
     9901 agatataaat tcatatcctt tagcttttaa ctcatcacga acactagaaa aatcttctgg
     9961 tgtagttatt atttcataac catcttcttc tgttataaaa tcttcagctc cagcttctaa
    10021 tgcaacatcc atcaattctt cttctgaaac tccatctcct aaaccaacta atatttgtcc
    10081 ttttttatca aacataaaag acacacatcc actagttcct aagtttcctc cgtttttgtc
    10141 aaaatagtat cttacattac cagcagttct gtttttattg tcagttaaag tttctactat
    10201 aacagcaact ccaccaggtc catatccttc ataaactata gtttcatagt cttctccagc
    10261 acctgctcca gcacctttag caatagctct atctatatta tcatttggca tattgtctgc
    10321 cttagctttt tctatagctg tttttaacgc tgcattgtac tctgggtctg ctccaccatc
    10381 tttagctgca actgctattg ctctagcatg tttagtaaat atctttgctc tttgagcatc
    10441 ttgtttacct tttctattaa ttatattacc tatacgtccc atatttccac tccttaatac
    10501 gtacaattaa ttattctaat tttcatcact tgtaaatttt atcacaaatc ttataaatag
    10561 taaattagaa cttaggaggt tgtgaaggcg tttttctctt atgttcactt aatctatgaa
    10621 gtctttcaat tatctcttgg tctcttttag gaacttcatc caatctgcct tctaacacag
    10681 catctatcat attataagta gttcccattt catcttcatc tgtttgacct tcccaaagac
    10741 ctgctgaagg agctttgttt attaaatctt catgaacacc aagctctttt gcccattcat
    10801 acacttctcc tttagttaaa tttgcaatag gtaaaatatc aactccacca tcaccaaatt
    10861 tagtaaaata tcctgtgtgt atttctgcag cattgtctgt accaacaact aagtatccta
    10921 gattgttagc aattgtataa atagtactca ttcttactct tgctcttaag tttgcatctg
    10981 tcatctttaa atattcttct ctatataaat gtttatcttt taaatttcct actaccatgt
    11041 ctaatatagc actttgtggt tctataaggt ctaaatcaag atattctata tcacatccct
    11101 ctataacctt aagtgcatct tctctatctt gaggattact ttttatgctc attataactc
    11161 ccatagagtt ttctggaaat gcctttttaa ttaaattagc aactactgct gaatcaattc
    11221 ctccagatac accaacaatt aatccttttg catttgcctc attaacctta tttataagcc
    11281 attctacagt tttgtctatt tgtattttta tatttgacat tgttatctcc tctcaaattt
    11341 gctactttgt tttaatatat tataccatat attaatatgt tgttttaata tgtttttttt
    11401 atgcaaaatt aaacaaatat gaaagattat atttaatctt attttatata aatataattt
    11461 gcctattttg gtaaaactat ttcaaagggt gatttttatg aaaaaaactg atggtttaaa
    11521 gaaaaaatac tttgatttta acttaaaaaa tacgataatt ggagttttta caggatttat
    11581 aaatggagtt tttggttctg gaggaggcac tcttttagtt ccaatattaa atgatatcgt
    11641 taaggtagaa gaacataaat ctcatgcaac tgctctttct ataataatat tcttaacgac
    11701 aacaagttct gttttatatg tatctaaagg tacttacgac gttaatttaa caattaaagt
    11761 tgcagtcgga agtattcttg gtggtattat aggagctaaa ttattaaata aggttactgg
    11821 aaagtttctt agaatttctt ttggaataat tatgataatt gcagcattaa ggatggtgtt
    11881 ttaatgttat ttgctctaat tggatttttt gcaggaatta ttggaggaat gggaatgggt
    11941 ggaggaacaa tccttatacc tgcactcgtt ttacttgctg gcatagacac taaaatagca
    12001 caaagcgtaa atttactttc atctatccct atgacactta tagcacttgc tatacatata
    12061 aaaaataaaa atgtaatttt taaattggtt atacctatag ctgtgtttgg ggttttagga
    12121 gctgtatttg gttcactatt agctaattat ctatcttcag atatattaaa aaaaatattt
    12181 ggggtatttt tacttttagt tggtttattt gaagtaaaaa aaggattctg tgcaaaatct
    12241 aataaaaagc cattaaattg atttaggtta aatcaattta atggcttttt acttaaaaat
    12301 accaattaat tatttaagat attgactatt acaataacct tttagattat agtaaaattt
    12361 ctccattttg ttcagacaaa taaaattcct ctcctaaaac tatttttcca gttccacttg
    12421 ttatatcaat cattttttct gataatttat caacatcttc taatcttgaa tatactacta
    12481 tctcaacatt atcttcatat atagtatctt ttataaaata ccccaaattc attaactcat
    12541 tttgtacttt tccaagttga gtatagtcta tcttaacctt aacttcttga tacattacct
    12601 tatagattat cttgcctgat tcaagtccta acttagcacc ttttgtataa gctctaacta
    12661 gacctcctgc acctaatttt gttcctccaa aatacctagt aacaacaacc actacatctc
    12721 tcaaatcttc tttttttata acctctaatg taggtatccc agctgttcct tgtggttctc
    12781 catcatcact atatctttgt atattcatat ttttacctac agtataagcc cacacattgt
    12841 gtgtcgcatc tttatgcttt ttctttattt catttataaa ctctaaggct tcctcttcac
    12901 tctttatagg cttagcatat ccaataaaaa cagacttttc aatcgttatt tcatccgttc
    12961 caaattcatg taatgtcctg taattgctca ttatacttcc tcctatttta atcattttct
    13021 aatatacaca tcaaatacat atttatttat aaaattattc tataaaaaaa taaatggact
    13081 tttaatattt ctttaatcaa tatcataaga caattatata ataaaattgt atacttttta
    13141 atttttattt taaatatagc ttactgattt taaatgtaaa ttactaaagc tctaaattga
    13201 taaatcataa cttaaacaag ctatataatt tatgcttaaa actgcttcaa ttaaaaaagg
    13261 aaggggctat cccttcctca gaatcctcta aattcacaat taatttgctg gaacatcatc
    13321 gccctctgaa actaatttct ttaattcctt aaacttttta taagatactt ctactaaagc
    13381 ttgctcttta tgatgtgata acatttctaa agcatccttt actttataaa atccaccttc
    13441 ttgaaattca ggtgcaaata cacagtcagt gttacaagct tccataacat accacattat
    13501 tgcattacaa acttcttgtt gtctacttct tgagaaaaat tcatacatag tatcgccagc
    13561 cacatctatc attttagcat ctatgccagt ttctacttta actctttgaa cagcactctc
    13621 atatggaaga cctcctccta gtatctttcc ttttggaagt gtccattcac ccctatcatt
    13681 ttttacaata agtactttat tagcataaaa cactactcca cctgcacaac gtcttactat
    13741 catttgaaac ccctcccatt aatttattta ttaccttgtt aaactttaga aataacatca
    13801 ttaagtaaac aaattgcttt aataaaaaat tactttttca aattttttgc attttctaat
    13861 gacttaatgg cttcgtcata agctctaagc acatattctt tttcaaaatt cttattcttg
    13921 tctttcaact gttgtaaaat ttttaaactg ctttcatctc ctaattttga aagagctttt
    13981 gcacaatact gcctagtctg tgcatttttg tcgtagagac ctttttgtag tacttctcta
    14041 ctacttggtg attcaatctt tctgattgct gaataagtta ttcttctaat atctgagtgt
    14101 ctgtggtttg tgagctgatg aagcaatttc aaaaatctat catcttttag ctcacctgtc
    14161 gcccaaatta aaacaattaa atcttcagca tttttttcta caaggattct tttgaaaacc
    14221 tttctcttaa agtataccat tttttcgtcg tctaagctat ccataaaatc aagtctctta
    14281 attttatcta gttctaaaaa tttatctaaa atatccttag acgcctcaaa atcatctttt
    14341 tgcatttcct ttatttttaa ttttgcttgt ataagttgct cacttgcttc agtacttgaa
    14401 atatttctaa ttttactaat ttgagacact gttttagatt ctttataaag aagataggtt
    14461 ataaaataat cttcaaggtt atctatattt tcccagttta tatccatatt caacctattt
    14521 ttctagtatg tactctctat agatattgaa atcttcttca tctaaatcta catctagcgt
    14581 tataccattt tccccatact caaaattttc cacattatat ttatctttta ttctactaaa
    14641 tatatcacct ctctcataag gtaacatcaa gcttactgaa taagtatttt ccattaaagc
    14701 aatttctatc atatttaata acttatccat atttatgcct tgttttgcag aaatatacac
    14761 aatatcttct tgacttttag gatatatatc caattctagc ttgtccactt tattatatac
    14821 aagtatatgt tttttatcat ttacaccaag ttcttttaat acaccttcag tcgtactttt
    14881 ttgcaattca taactagtat ttgtcgcatc aattacatgt aagattaaat ctgcatactg
    14941 tacttcttcc aatgttgctt taaacgcttc tactaaatca tggggaagtt tacttacaaa
    15001 tccaacagta tctactacta aaaattcttt tttattcggc aaaagagcct ttctcaaggt
    15061 tacatctaaa gttgcaaaaa gcatatcttt tacaaaaact tccttttcct gttcataatc
    15121 cttgtgtgtc tttattaatt cgttcaacag ggtagatttt cctgcatttg tataaccaac
    15181 aagtgctaca atcggtatat ttgactttaa acgcttaact ctctgtgttt ctctattctt
    15241 ttttacttct ttaagttcac gccttatatc tgctgcttta ttaagtatat gtctcttatc
    15301 tatttctagt ttttgttctc caggacctct agtaccaatt cctgcacctg ttctactcat
    15361 ctcaccaccc attccataaa gtcgtggtaa tctgtatttt aattgtgcta attcaacttg
    15421 taatttacct tctttactaa gtgccctttg agcaaatata tctaaaatta aagtagttct
    15481 atctattact tttctaccaa caacattctc tatatttctg atttgagcac cagataattc
    15541 atcattaaaa attactaaag tagcatctaa agaatcacta tacgctctta tttcttctac
    15601 cttacctttt cctatataat aagctgcatc tatagaatgt ttattttgaa ttaagctacc
    15661 tacaacttct gccccagcag cctttgttag ttcctttaat tcttccatag attcactagt
    15721 gtctatatca tcattttttt tcactattgt agtcaaattc aaacctacaa gaagtgcttt
    15781 ttcttgaatt tctttcactt aatcacctca ttttttgtta taaagcatat tctaattaca
    15841 aaatacactt acattacttt tacattattt ttctgttgac taattatacc attaatacta
    15901 tgattaataa tactatatta tcgactattc ataaaattat ttagtataat tatattatca
    15961 ccaaaatctt atatagtata aaaaatttaa attttattta attaggagga agatatgggc
    16021 gaaaattata agttttttaa tcacaaagat tgtgaatttt tcccttgtca taaaactaat
    16081 aaaccagaag agtttaactg tctattttgc tattgtcctt tgtatgcttt aggagagaat
    16141 tgtggtggaa actttaagta tacagataaa ggtatcaaag attgcagtag ttgcatgtta
    16201 cctcataaaa aagataatta caattacatt atgggaaaat tccaagattt agttaaaatc
    16261 actagtaaaa agtaatttct attggaaata gctatgcata aatatttatt gactactctt
    16321 agcctaaata ttattacata gctattttta ttgtataacc tttaatataa tttgtttttg
    16381 ttattttatt ttaaaatatt tacataattt atacattaca aatagtaaaa tacttgacaa
    16441 taaaattaat attaaaatca tcattcctga gtgaaaaaaa aattcctctg gcaatatatt
    16501 tataactggg tctaaattgg gattaaatat ccaataatca tttctaaata ataatttatg
    16561 aaaaataata aatgactttt caaaattcaa taaaattgga actgttaata ataatggcat
    16621 cattataagt gttatagatg tagttttcaa gatttttata tttttatttt ttacactcaa
    16681 tataattcct actaaagaaa ctatcaacaa taatttagct aatttattta tattttgaaa
    16741 tatattccta acttcttcaa aatgtatctt cccttgtgga gaagatttta atgttggtaa
    16801 attaaactct gatacattct tatttaagtt ataatcgatt agataatcgt agttcaattt
    16861 tatatcatct ttagataaac cagataactc tgatatgttt aaataatcaa tgtcaaaata
    16921 ataaagtttt ttaaatccaa cagtaaaatt aataacacct actattataa caatactaat
    16981 acaaactgaa aaaagtacat ttagaaactt tttcataaaa tccccccagt aaaagttaaa
    17041 tcactacacg attttagttg taaaatcttc tatattccat acatcatcaa caatttctga
    17101 ataaaattct ggctcatgac ataccaaaag aactgttccc ttaaactctt taatagcctt
    17161 cttcaattcg tcttttgcct caacatctaa gtgatttgta ggctcatcta atactaagaa
    17221 atttatattt tttagcatta ctttgcaaag tctaacctta gcagcttctc caccacttaa
    17281 tactctcatt tggctagtta tatgttcatt tgtaagtcca cattttgcaa gagcctgtct
    17341 aacttcaaag tttgtaagcc ctggaaattc actccaaact tcatccatag gtgtattact
    17401 attttctctt gagctctctt gttcaaaata tccaacttct aaatagtcac ctagtttaac
    17461 atttccttca aatggtttta ttatcccaag taaagttttt aatagagtag attttccaat
    17521 accattcatt ccttttaagg caatcttttt tcctctttct aaatggaaat taagtggttt
    17581 tgtcaatgct tcatcatatc ctaaaactaa attttctgtt tcaaaaatta ttttactagc
    17641 tgctctagca tctttaaaag caaaagtagg ttttattttt tcttttggtc tttctaatat
    17701 ttccatctta tcaagttgct tttgtctact gttagccatt cctctagttg ctactctagc
    17761 tttatttcta gctacaaaat cctctagtct ttttctttct tcaacttgtt tatcataagc
    17821 ttgttcttct tgacgtttct ttatatcatt aagtcttaca aattcatcat agtttccttt
    17881 atatctattt agctctccat tttccatatg atatattaca ttacatgtat tgtttataaa
    17941 ttcaatatca tgagaaacta agacaaagct attctcatag tcttgaaggt acttagtaag
    18001 ccatgttata tgctcttcgt ctaaatagtt tgtaggctcg tccaatataa gaatagttgg
    18061 attttcaagt agaagtttag taagaagtac ttttgttctt tgccctccac ttaagtcagt
    18121 tacatcttta tcaagaccaa tttctccaag accaagacca tttgcaactt cttgtatctt
    18181 tgcatctatc atataaaaac cactattttc aagtatagtc tgtatttctg ctgtttcttc
    18241 aagaagctta ctcatctcat catcactagc ttctcccatt ttgtcataca tagcaatcat
    18301 ttcttgctct aagtcaaaca tatgcttaaa tgcttctcta agcacttctc ttatagtttt
    18361 ccccttgctt aataccgtat gttggtctaa gtagcctact gtagctcttg aagaccattt
    18421 tatatttcca gcatctggca taagcttctt tgttattata tttaaaaaac tcgattttcc
    18481 ttctccatta gcaccaacta gtgcaatatg ttcacctttt ctaagtctaa aggatacatt
    18541 ttctaatatt gttctcgcac caaatccatg actcacattt tctactacta gcatttcaac
    18601 acctctcaaa aaaattttac acattctata ctataatata ttctttttaa acttaaatca
    18661 agcattacca atatttttag ttatatttac gacaatttaa cctaaaataa acttcacttt
    18721 tgtgttatgt acaataaaaa atagagataa aaattaggaa aataatacca acctaatttt
    18781 ttctctattc atactctatt taaaatactc atctaatcca tcagctatac actgcatcat
    18841 ttttctttga tagtctggat ttgacatcat ttggtcttca ttatagttac tcataaagcc
    18901 catttctact aatacagctg gaacttttga ccagttgaat ccagtcaaat cacctctttg
    18961 aatgattcca ttgatttgta tacctgattg ttccatattc tgtttgataa attcagcaca
    19021 tttattactt tcttcatata taggagcggt atattttcca tctttttcag gaatcaatat
    19081 agatgctcca gtttttgagg aattatttaa actatctgca tgtattctta caaccatatc
    19141 tgctttttta tcattagcaa gtattgctct ctctgaatta cttatattta catcatgcgt
    19201 ctctctagtc attattacat tataaccttt agattctaat atattcttta aaacaagaga
    19261 tgcttctaag tttaaaacat attctggttt ttttgtagca ataccctctg ttcctgaaga
    19321 tactctcgct tttttagagg aagaacctgg agctactggt tctaaattgc tatctccttt
    19381 tccttgatgc cctgggtcta tacaaattaa aagtttttta tttttttgaa tttcattttt
    19441 attatctgac gatttgtcct ctgataactt atctttatta cttttagagt tagatttgtc
    19501 ttcttcttta tctttattat ttttgtttga attttcacct ttatctgctt tttcatttgt
    19561 gatatttcct gaactaatca aatttgtagt cttgtaaaaa ttactaactg gatttgatgt
    19621 tcctataatt atgattccca tggcaattat acaagtaact aacaatctat attttttcat
    19681 tttttgctcc tttcttatgc tagacagtta ttgtttattt ttatttatat gaatatgtat
    19741 ttattttatc atatacacta tttattttat ttatttttat gaaaactaag gtgttattga
    19801 gtcagttttc caagcatcaa aacataattc ttgcacaaca taatatagaa gcagcaagaa
    19861 aacttcaatt ctattattaa aataatttaa taagaaagag gtgttttatg caacttaaaa
    19921 attttcattt taaagataat actttaagta aaaaaaccaa cttagctaag tcaaaattta
    19981 caattgtttt aacattttta tttttattat attttttctc aaataattta atttatgcac
    20041 aaaatttaca aaaaaatgaa cctgaatatt taataccaat tggaaatgta cttcaaattg
    20101 atgcagaatt aaaaaatatc atagttagaa accctggaga agcatctcca tttagattag
    20161 gtgatgctat agtaaaggta aataatgctg aggttgatgg atatagtgat tttgctaata
    20221 ccttaaacgc tttaccagaa gaaaagcaag tatctatttt attaaataga ggtggacaac
    20281 ttataacaat gaaaacaacc aaacacatat tagaaaaaat tagttttaac aatttacttt
    20341 ctggatttgc cactttaacg tatatcaatc cagatacatc agagtttgga gctgtaggac
    20401 atccaataag tgttggtaat gcaagaaaaa tacctattaa aacaggttca atttctacaa
    20461 ctaagcacct taatatagaa aaatcttata aaggtagtgt tggatgtata aatgcaaaac
    20521 gagaaaatat tattggtagc tttacagaaa atactgattt tggaataaga ggtcaaatta
    20581 ataactttga tatttccaag ttaaaaaaat ataaagtagc atctttagat gaagttaaat
    20641 taggaaaagc tcaaataatt ttacaagata actttaatga gtgtaaaaaa tataatattg
    20701 aaattataga tatagaaaac caaaaacatc cagaaagtaa aagttttaaa attaaaatta
    20761 cagataaaaa gcttttaact caaactggtg gtattgtcca aggtatgagt ggtactccaa
    20821 tagttcaaga taataaaata atcggagcag tatcacatgc aattgaaaat gacccagctg
    20881 taggttatgg tgtatttatt aaatggatgt tgtaaataat ataaataaat aagttttaag
    20941 acgttattaa gttattaata atatatttgg tctaaaggta attttattta acctacagac
    21001 caaatatatt agatatttta catagtataa aatataaatt ttgactaaaa ttatattaat
    21061 attatttcca aaaattttat ttataaacta ttcctttgaa tttatttaaa aatatacaac
    21121 tttatattac ttgttagtat tttttccagt gttaggtaaa acatttccta gatttttttc
    21181 tggaatattt acataacttt ctggaacatc acctactatt atagtttcac aaataggtat
    21241 ttgagcttta atttgttttg ttgaagttat aagtggtatt actactttaa cctgtgtttg
    21301 agcttctaaa tatattctat gcctagtttg atttatacct gaagactcaa attccgtttt
    21361 aaagtttact gatactgttc ctataggttc aatagacact tcaagtttag gaccgtattt
    21421 agctaatata ggacttccta atgctgttcc tataggtatg taagaacttg ctgtcttatc
    21481 cttttttaat tcatcttgta tttctaaagc tattgcagat gcaatttcat tcatcattat
    21541 agtatttgct tgtatcatag ttattttgcc attattatca agctgtatat ccattaaatc
    21601 ttcataattt atttttcctt ctaccatctc agcaacagct ttatttatag acctgtttgc
    21661 taattcaaga gctttagttt ctgctaaaac tgttattgtt ggtcttaaag ttttatctat
    21721 atatataaaa ctgcctataa atacagacaa gaaaagaatt actaaaaaaa tagctataat
    21781 ttttctaaat tcattttttg tttttctatc tactattcta ttcaaaatta tcccctccta
    21841 tttatttata tgtagctttg gcataatttt tataatattt gtcaaaaata aataaaataa
    21901 aaatatagac tttttaatat attatgttta tacatataca atgtacagaa tattatagca
    21961 aattcatttt ttctattaat tacaaaacta ctcctatttg tgttataata ttgcattaag
    22021 taaggaggtt aaaaatctta tgaataacga taatgataaa aatggaaata aaatcagaag
    22081 aaaaaaagtt agctcatctg gtaatacaaa taaaccaatt aatagaactt cagctaacaa
    22141 aactcgttca acaaaaaata agaaaaaatc taaaaaaagc gataaattta aaaaactaag
    22201 agtatttggg atagtatttt tagttttact agttgttggt acagcaggta ctgctggtct
    22261 agtatttgca tcactaagag atgtaactcc agttacagaa gctgttttag ataaacagac
    22321 aaaccaaaca actacaatta aatacgctaa tggaaaaaca ttatctacag ctccaagtgt
    22381 aaataaaaag acacccgttc cattagataa gatttcccct tatcttcaac atgctgtaat
    22441 tgcaatagaa gatgagcgtt tttatgaaca taaaggtgtc gacattaaag gtttatttag
    22501 gtcagtatta aagaccctta caggtactaa gcaaggtggt agtactattc ctatgcaggt
    22561 atcaaaaatg ttgttaacaa ctgaacaaca aactatacct cgtaaaataa aagatattta
    22621 ctatgcacat gagatgagta aaacagtaag taaagataaa atactagaaa cttatttaaa
    22681 taacttcttc gttggtagag gtctagcagg tgctgaggct ggtgcacgtg gttattttga
    22741 taagtctgca gctgacctta ctctagcaga gtcagcactt cttgctggtt caactaaaaa
    22801 tccatcaaga ttttcagcct ataaaacttc taagttagag ggaaatgaaa ctaaggagga
    22861 tttagaaaat aaattattat tttttgttaa cacaactgat gatgatttag atgaccctac
    22921 tcaagttgat tttgatatga ttgaaaaaat taaatcttgg gaccttatat ctagtgacac
    22981 ttatagacaa ctaaaagcag gtacattagt tgttagaaag gctgtaagta atcctgaagc
    23041 taagaaaaga caagaaattg ttttaaagaa aatgttagac ttgaaatata taaaacaaag
    23101 tgaatatgat gaagcaatca aagctaaaat agaaataaaa ttgcctaaat catcagataa
    23161 agtttcttca tctgtagaag accttatcga aagtgaagtt ataaatgctt taatggaaca
    23221 aggacataca aatgatgagg ctcaaaactt attctataat ggtggtttaa ttgtaaatac
    23281 aactatagac cctaaaatgc aagatgcttt agaagaagag tttgataaaa atagcaattt
    23341 cccaggacat atggtcggtc ctgatggagt tagccaacca caagctgcaa tggtaatctt
    23401 agattataaa aatggtgaaa taagagcact agctggagga agaaatataa gtggtagaaa
    23461 aactttaaat cgtgctacta accctcatca accaggttct tctataaaac ctttagcaat
    23521 atatacacca gctattgata ctctaaaaat aacacaatca actgctctaa gtgattctag
    23581 aggaggatat aagtttgaag aaaataataa atggaatcca agaactacta ctgctggtca
    23641 tggctctatg agtttacgta aagcacttgc taaatcttca aacacaatag ctgttaagac
    23701 tgctgaaatg cttggagact cttatgatga atgtgtagat ataatgatgg attacttaaa
    23761 gaactttggt ataacaactt taaaaaataa tcactcaggt tcatctgaag caagtgatag
    23821 aaaattccca tcattgacac taggtggtat ggcgaatggt attactccgc ttcaaatggc
    23881 tgctgcttat ggtacattgg caaatcaagg tgtttatgta gagccttcta tttttactac
    23941 tataactacc tttgatggtc aattattagt taaaaaagct cctgaagaac ataaagttgt
    24001 agaccctgaa gtagcttacg ttgttacaga tatgttagaa agcgtaatta ctgaaggtac
    24061 tggtggtgtt gcagcacttc caaatggaat gcctgtagca ggtaaaacag gtactacaaa
    24121 tagtgcatat gatgcttggt ttgtcggtta cactccttat tatgttggtg caacttatat
    24181 tggagatgat gctggtagaa aagatgattc tggtaacact ataaaacgta gagaagtacc
    24241 acatggaagt actagtactg caaaactatg ggaaaaagtc atgcaaaaaa tacatgctaa
    24301 tttaacagtt actgaatttg aagttcctaa aaacgtatat tttacaaaaa ttaatttaga
    24361 tgatggagga aagcaatctt ctggctctaa agcagcattt attgaaggta ctgctcctac
    24421 taaagtaagt tctcaaccat catctgaaga tacaaaaaaa ccagataata atcaacaaca
    24481 agaaaataat aataacaata ataactctgg tgataatggt ggcggttcta ctcctcctga
    24541 taatggtgga aataatggtg gtggctctac tactcctcct gataatggtg gaaacaatgg
    24601 tggtggctct actactcctc ctgataatgg cggaaacaat ggtggtggct ctactactcc
    24661 tcctgataat ggtggaaata gtggtggtgg ctctactaat acccctgatg gtggtggaac
    24721 tccagcaact taataaaaaa taaaatttga ataaaaatat aaggagttgt ctcaaagtga
    24781 taaaaaaaat cactttgaaa cactcctttt tttataatta aattatatta tgtattttca
    24841 taaaaaagag aaatctgata aagtatatta tactctatgt ttgtagcttt tctttgatgt
    24901 ttattgacac atttatatgt ctttgctaca acgataatat tagttgaaca acataaatta
    24961 ccaaaagaag gatagaaaaa tgcaaccaaa accaattgtt acaaaacaag atattattaa
    25021 cattgcaatt aatttggtaa gtatctcgct tatgagcaat atataaaatt agcagatatg
    25081 gaatttgaaa tgctgttcta atacataaca gaacgaaaaa acagtgcata ccattttcct
    25141 acaatacgca ctgtttcgtc tcaatcctgc atataaacca ttaagttagt tttgatgtta
    25201 tacttattta ttggctttta cctaaataga actctcctta tttatgtaat caaataaata
    25261 ttttattttt taagtcttaa actatatctt ttatttctag ttgtttatat attgtaaata
    25321 tttatatcac aaattatata aacttaacat ttttctaact actgtatacc aaatgtctga
    25381 aatctattta atttaccata tcttttaata agcatttccc actcttcttt atcatagaaa
    25441 tcacacttat ttctaccaaa tagcttggca acttcaattg caaatctacc agctgaatct
    25501 aaatcactaa aattagttgc acctgtagcg catccagcaa caggcatctc tgttgtaatt
    25561 gctaccccta ctattggtgc atctgtagct actgctggtt gtaaaatact atttaagtga
    25621 tacagattgt ttccatatgg tgttatatct tgaatagata aagggaatac aaatggagac
    25681 ttcccagtta cagtctgcat aatatctaaa aggttatcac tagtttttaa tatgtagccc
    25741 tctttaacag ttggtgatat tgcaaatcct ctagtattga ttaccctatt tcctttagta
    25801 gtatctatag aaagtattgc atcacaacta ctatcaactt cattttcatt catagtcatc
    25861 atatcaattg gagaatccat aaaaggagta ggatagtgtt ctttagttgg agcatctggg
    25921 caaatatgag ttgaaattac aacatcacca tctaatatat ccccttttcg ttgcatatcc
    25981 aaaagtttag cagccactgc aattgctacc aatgctccat caccatctga gacaaaacct
    26041 ataacttctg gtcgtgctcc aatccctcct agtctaccta aaataccaag agtaggagca
    26101 tctccacctt ttgattttcc atttttacca ggaattgtaa gctttactaa atctgttgag
    26161 cctttacttg aagacaattc ttttacagtt acatctactt caccataacc ttgtaaataa
    26221 gtttttactt cttccccatt agcatctgct ttatctaaaa tgtcataaac ctctattact
    26281 tgttttaata tcatgtctaa tttgatttcc tttcttaata tattttaaaa ttatatatta
    26341 tttactatac aaaatatcta ctccacacat tgctagcacc ttaattgctt ttataagtgc
    26401 tactctacct tcttccccac cagctgcaac agcaaattca tctgtatgag ttgcagtatt
    26461 ttcttttaat ttgatatacg cttgtattgc aggtatctca tgagttaaat ttcctgtatc
    26521 agttgaacct ataccttgac ttaaatctct ttcaacatag tcttcaccca aaacttcaaa
    26581 attttgtcta actatattca ctaattcaga atcattctta atctctttgt atatttcatc
    26641 taattgaact atttccacac tagttccagt agatattgca gctcctttag cacaattttt
    26701 aagcatttca caaatctcat ttaaatattc tatgcttaaa gctcttacat taaatatagc
    26761 tgtagatttt tcaggaatta tattatgtat gctacctcca tcagttataa ttccatgtac
    26821 tcttgcataa tctttaagat gtaatctcat actatttaca ctattaaata gtgctattac
    26881 tccacttaat gcactttttc cttcccaagg aaaagcagca gcatgtgatg ccttaccgct
    26941 aaaatcaaat tttaaattaa cttgagcaaa tgatatgtca tcaggcattg aagcatcact
    27001 tggatgtaaa attaatgcag catctacatt attaaataca ccctctttaa tcatagttat
    27061 ttttccacct actctttctt ctgcaggtgt cccaaaaact tttacagtcc cttctatatt
    27121 atgttttttc atgatttctt ttaatatgat acctgcacca acagaacttg tccctatgat
    27181 gttgtgtcca catgcatgtc ccattcctgg aagtgcatca tattcagcta aaaaagcaac
    27241 tgttttccca ttagttccat ttgaataaac agcttcaaaa gatgtttcta atcctcctac
    27301 acctttagtt acattaaact cattttcttc taataaatca cataatgctt tttgtgactt
    27361 atactcctca aatgctaatt ctggatttga aaataaataa tcagaaactt tttcaaatga
    27421 tgtctttttt tcttcagaca ataactttat ttcctcttta atttttactt ttaattcatt
    27481 catatttact acctccttaa agcattccat ttaattttaa aactgtttga gatataaaag
    27541 cagaaccaaa gtaagtagat gtcataacta taaatgatat aactactaac ttccaactca
    27601 aagtctttaa tatatctaat tggttaccta cagagattcc tgcaaaagct aataatggtg
    27661 ttactgtaga cataaaatta atttttccta cattcgttgc tatgatatcc cccactggag
    27721 atattggaag tgataataca aatgcaacta atgtagccca tgcaaaacct ggtaaattag
    27781 gttttttaac aaaattcttt attataatag caattatcac caacaaaaat ccagatacac
    27841 ttccaatcaa taaatcctga gcctgagtct taagtgctat catttgtcca aagcaaataa
    27901 taatatatat aaacaatact atttttatct gttccataat ggtcttaaaa gttttttcca
    27961 tatatatatc ctcctttaca atttattact tgttcttgct gtttttcttc ctctaaatct
    28021 ttcaataact ggagctactt tgctataata gtagttggct actggtaaag ataaaaataa
    28081 ttctatatat attccagtaa cagctgtaat caatccacta gtcgctgaat atgctaaaat
    28141 ctgctctgac atttgtggaa ctgtattcat taatgatgct gttgcagctc ccatcattga
    28201 accactaccc attcctgatg ccattgctaa agcatatgga tgaaatccta aaagcacacc
    28261 cactggtgct aaaaatgaaa ataataatgt tccaaatata ctaccactta tataagttcc
    28321 tagtgttcct atcccttctg gtgaatttaa tccatactta tctccaataa ttcctagcgc
    28381 tgtatcacga cataatgaaa aagtaccacc taatgcactt cttccaagac ctaatgctac
    28441 tccaacaggt aatgctatca acattgtacc catatgacca aattcttgta ataaaagtgc
    28501 tggtcctgct tgaagtaata taccaacttt aggccctgca ttaattccaa acattattcc
    28561 taatggatat agtgttaaag acaataaata tggagataca tttatttcat tatcccctat
    28621 aaattttttt aaggctggta taactctccc taataaatga ggagaaacag ccattcctat
    28681 gaatatagcc catagtatac taagtaaagt tacattaatt cccataactt taaatgaaat
    28741 aggtccaatt aattctgcca atattgtgat tataaaggct gctattatgg catttctaat
    28801 ccctgctttt tctttcattt ctatacctcc ttgtaatttt tataattttc ttataatata
    28861 attgttagtg attttattat ataacctatc attgataatg tataatatat atttattcat
    28921 catttttata tacttttagt tatgaatcaa aaaaatatta tccattcatg atataaaatg
    28981 caaacaattt attaatttgc attattaaaa taatagattt tcaaataatt gaataaaatt
    29041 attcattcat attataaaaa ttctctcaat aaataaagga gtacaatgta cttatataca
    29101 cctactcctt ttaattttat ttatattatt tgtaaaaaca cttcacataa tctataatat
    29161 tttttataaa attttaatgc ttaaaaactt actattttat tcttttaaca ctatttcgga
    29221 ttattaacct tggatatagt tttcttggaa tatgctctgt gcttttttta tttattatat
    29281 ttactaaact gtctactcca ttttttataa cttgctctct tgggtcatct attgttgata
    29341 aatgcgacct gaagtatgat attaattcaa tattattata ccctattata gaaatatctt
    29401 ctggtacatt tataccataa gtagttttta attcttgtat tatagaaatc gctggtacat
    29461 cttgttgtac aaacatagct gaagcttttt ttattttatc aatatatttt tctaaaaatt
    29521 caacttgaga ttcaaaatcc attttagatt taatgacttc agtctttaaa tttgcctctt
    29581 ccatagcatt caaatatccc ttggttctat cttcatgcat ttttgaactc ttatcatctg
    29641 aagttactgt tattatatct ttatgaccat ggtcaattaa atgtttggta gctatataac
    29701 ctccatatac gttatcgtcc caaaagaaat tgtctacttc tcctataaaa gatggtttaa
    29761 aatatataaa tacatgtgga aaattattgt cttttaaaaa atcatactct tcttttttta
    29821 ttgattgaga cacaattact aatccgtcaa ccatttgtcc atttaccatt ttatatacat
    29881 tactatcacc actaatgtta ttattcggtt gtattataaa atcgtattta ttagtctcaa
    29941 tagaatttat agagctgtcc attatatcac taaaaaattt tctagtatct tgatgattaa
    30001 aattatttga aaagattacc cctattctgt tggtttcttt ttttgccaga tttcttgcat
    30061 ttacattaaa atggaaccct agtctatttg cctcttctac tactttcttt tttgtttttt
    30121 cagatacatt aggattattg tttaaacacc tagaaacggt tgaataactg atacctagat
    30181 tccttgcaat atctttaata gttaccatct ttatccccta cttcacttca ttttattttg
    30241 ataatataat actacactat gttgtaaata attgtcaact tcaattatgt aaacgcttct
    30301 ttatataaaa aataggtgga atctataaga tatccaccta ctttataaaa agttattatt
    30361 tctaaaagtt attattctct taaataaaga tttatggttt tgcttttgga gtaaatacga
    30421 ctgacataat atatccaaag aatatggctg ctgctattcc accagccgta gcagttgtac
    30481 ctcctagaaa aatgcctaaa aaaccatcac tctgtattga ttttattact cctgtagcaa
    30541 gtgaatatcc aaatcctatt ataggaactg ttgcacctgc tgctgcaaac ttaactaatg
    30601 gctcataaag ccctaaaaaa gttaaaacta caccagttgt tacatacgtt accataacat
    30661 atggagtttg cattttaaaa taatccatca ttacttgggc tattaaacat ataattccac
    30721 ctacaataaa tactcttaca tagtccatta acatatatat cacttcctac tcatttacta
    30781 ttactactgc atgagcaaca catggtattg tctgcttttg tagtgtactt gttggtgaaa
    30841 gtagtgctcc tgttgatacg agcattactt tgttaaattc tttttttctc aacttatcat
    30901 atatatatcc tgcaaatact gtagctgaac atccacatcc acttccacca caatggacat
    30961 cttgctcttt aagattaaac atctctatac cacagtcagt ataaactttc gatatatcta
    31021 tacctttttc ttttaaaaaa tcttctgcta tctgttttcc aagagtacct aaatctccag
    31081 tagcaattat atcaaagcta tttgggtcat cattagtatc ttcaaaataa gagtagatag
    31141 tatctatcgc tgctggagcc atagctggtc ccatattatt gccatcatca atgccctcat
    31201 ctattacttt accaactgta acatatttta cctttggtcc ttctccatta ggagctagta
    31261 atacacttcc tgctcctgta actgtccact gtgctgtcat tggtttttga tttccaagtt
    31321 ctagcgggaa tctaaactgt ctttctgctg tacaataatg acttgatgtc cctgacagta
    31381 ctaagtctgc aaaaccacca tctataagca tagaacctat acaaagacct tctgccattg
    31441 tagaacaagc tccatatata cctaaaaatg gaatggccag ttctcttgct gcaaatgatg
    31501 ctggcactat ttgatttatt aaatctccac ctagcatata atttacatct gtcaattttt
    31561 tacctgcctt ttgtatagct tgttgagatg cagtctctac cattttactt tcagctaatt
    31621 cccaagtctt ctcaccatat aaatcgtcgg tcataatcat atcaaaatag tcttttagtg
    31681 gtccttcacc ttccttagga cctactatag ttccagttga tattattgtt ggtttatttt
    31741 ctaacttgac tgttcttttt ccaattcttt tatttttcat attttcacac ctttttaatt
    31801 ttgcatttta ctatttaatt ttttaatatt aattaaatat gcatgattat ctctcaacta
    31861 gctactttag taactatttt cagattttat acattcttca taattaataa aatttaaatt
    31921 aaataaaaat catctaaaac atcttaaaaa tataataaat aattccacat aaaatagaag
    31981 aacctatacc ataaactaaa actggtcctg caattttaaa tagatttgca cctacaccta
    32041 atacatagcc ttctctttta tactccattg ctggagatac tattgagtta gcaaaacctg
    32101 ttattggaat tatagaacca gctccagccc tttttcctat taggtcgtag actcctaatc
    32161 cagttaaaaa tgcccctata aatattaatg ttattgatgt tgcagaactg gcacctaatt
    32221 tatcaagacc tccaactttc atgtacaaat catttattgc ttgccctatc atacaaataa
    32281 ttccacctac aataaatgca agtgtatagt tttttaaata tgtaggtttt gggcttattt
    32341 ggtctacata ttttttataa tttttatcca tactaaacac ctctctaaag tattatttgt
    32401 taattttaaa aaaataaacc tattatttat tttgactatc taaagtttag tcaaaaaata
    32461 aaaaagatgc ctaataaaga aaaaatctat tttcccataa agacaccttg ttttaatatt
    32521 tttatttttt tatactcttt attattttaa tatattttaa taatttaaaa acttaacata
    32581 aaaaattatt acattttatt ttagtaatac atttattata ttattatatt ttgttattct
    32641 acatatcata aggattgtca tgatatgtat tcttttaact tagacaatac tttcttctct
    32701 atcctagata cttgaacttg tgatatatta agcatctctc ctatttcact ttgagtcata
    32761 tcttcaaaat atctgagaac tattatttga cgttctctct tatccaatct tccaagtatg
    32821 tcttttaaca atatgttgtc cactactttc tcttcttcac tttctccctt catgcttatt
    32881 ttatcaataa gacatattgg agagccttcc tcttcatgaa taactccttg taaatactca
    32941 acattgaaat tagcttccat agccataact aaatcttctt tttctacatc tattgcttta
    33001 gctaattctt ctatgctcgg ttctctaccc aattttttag ttaaagcttc actttccatc
    33061 tttgccttta cagctatttg ctttaacgac cttgacactt ttatcatacc atcatctctt
    33121 aagtatctct ttatctcacc taaaatcatt ggtactgcat aagtagagaa ttttacatta
    33181 aattttgggt caaatttata tattgatttt attaagccta tagaacctaa ctgaaataaa
    33241 tcttctctat catatcctat atttaaaaat ctagatacaa cgctcctaac tagacctaaa
    33301 ttgcttgata ttaatatttc ttttgcctct tcatctccat tttgaacttt ttcaataagt
    33361 tctagagtct cttcatgact aagaagaggt tttttttctt ctctggcaac agttacttcc
    33421 ataataaaac ctcacttttg gactttattt aggcacattt atttttttag tcatttcaat
    33481 tctagtccca ttatctttta cagaacttac ctctacatcg tccataaagc ttttcattac
    33541 tgtgaatccc attcctgatc tatcaagttc tggttttgat gtataaagtg gttccattgc
    33601 cttctccaca ttttctattc catacccttc atcttcaact ataatcttta tagtatttcc
    33661 ctctatctca catcttaaga aaacaaactt agaactgtct tcttcatatc catgtattat
    33721 agcatttgta acagcctcag agacagcagt ttttatatcc actaactcat ctactgttgg
    33781 gtctaactta gctgcaaagg atgctactat aactcttgct aaactttcat tttcagatat
    33841 tgccgaaaat ttaacttcca taatattatt catcacatac tcctccctac aaagaactta
    33901 gagcttcttc atacgtatca taaatgccaa taattttatt taacccagat aaatcaaaaa
    33961 tcttcttaac tcgtgaactt atattaatta ctgaaactcg tcccccttca ttagaaatct
    34021 ttttatatct acctatgatg acacctatac ctgaagaatc cataaaatta atattttcaa
    34081 aattaaatac aacatttttt acttgattta cacttaataa gttatctatt tcttccctta
    34141 tttcattggc tacatggtgg tctagttctg agcacataaa ttctatgtat agattcttat
    34201 gttctaagga ataatttacc atcaaaatcc ctccttcaat agttttgtaa aaatagtaac
    34261 ttttaatcaa ttctataatt atatttttat tccttcaatg aaatttaact agttttgtcg
    34321 tattatttct actatacttt cattatatgt tacctgacca ccaaaatctg atataccagt
    34381 gtctgtcaaa atattaggat ttccatgttt cttccaccat ccaacataca tttttactat
    34441 ataattacct actccatcat ctatatttat ttgtacattt atttttgctt tttttgacct
    34501 caatatcaca gtatctttat ccttgatacc tactttttta gccattcttt gatttatata
    34561 tgcttgagct atagattttt tatccataaa atgctgacta aataaagtat ccgcatgatg
    34621 gttagttaat aatctaaaag aaatattttc atttttatct tctatctctt tatatttatt
    34681 gtttatatat acaggtgttg gatttattcc caagtttttt atactttctg aataaagttc
    34741 gtattttcca gaaggagtct caaacttctt atcttcccaa gcaacagggt tatgtatagt
    34801 aaagtaattg tttttaagtt tttctatatc cagatttttg tcaacacact taagtggttc
    34861 aatcactttt tctaaataag tgctcttttc tacaaatgga taatcattta atctcatctt
    34921 tttggctagc tccataaaga agtaatattc atccatcaat ttatgtgctg gctttacagc
    34981 tctttcatta taggttatat atggattagt cattgaacta taaattatat cttcactctc
    35041 tagtgtattt gtacaaggta taaacaggtc acatagagtg gctgtatcag tcataaacat
    35101 atcaaaacat actttaaatt caatttttga aaacaccctc tccaattcta ctaaatctgg
    35161 cagttgattg agcatattgc ttttagttat cacagccatc tttataggaa tattatcttt
    35221 aattgactta ccagataagc tatataagtc atttgatata taatctgttt tatttgattt
    35281 tgtatcaggt tcatctgata cattatttat tttatttgat gtatttctta aagattcttc
    35341 tatgaattta ctgatattac ttacataaaa ctccctatct tgaccatata atttactatt
    35401 gtaagggtca gaatttataa cacttgggta aactttatta gcatagttta cccctccacc
    35461 actaaatcct atttgaccag ttatagctcc taaagcatct atagctctta ttgtgtttcc
    35521 accattttta tatttttgaa gcccatatcc aacatttata ctcgaatatt tgttagtata
    35581 taaagcaact aactctctta tatcattctc tttaacacca cattcatcaa tcaaaaaact
    35641 taattccaac gaatataaat atcttttata ctcttcaaaa ccaataacgt atgagtttat
    35701 atattcttca tcatataatt tatcttctac tataattttt gccatagcta tagctaaagc
    35761 tccatctgtt ccaggattta cctgtatata cttatctgct atttgagctg ttttcgtata
    35821 tatcgggtca atcactacta tctttatacc tttttcttta gcttttttaa ttatttgcat
    35881 agtatgaatt gtagtgtatg ctggattttt tccccacaca aatatacttt tactgtttaa
    35941 catgtcttct atcgcatggc tcttagctac tccaaaatca tatttttgag catgcatccc
    36001 tgcactccaa catggacttc ccttatgcct actgacacct ccataaaaat taaaaaatat
    36061 atctcctatg tattttagta cagacccact tccatattgg tcataatgca tgacagactt
    36121 tgatgtatac ttttctttat agtatgtaag tttttctgcc attatttcta tagccttatc
    36181 aaaagaaatc tctttccata cttcatcaac tttaagcata ggagtcttta ttctatcttt
    36241 atgatttaat ctatctaaat gagccatccc ttttttgcat ataaaacctt ttgtgtaagg
    36301 atgattttta tctccttcaa tttttactac attatttcct ttagtataga cattgaattt
    36361 acaacaatca tggcaatcta gtgtacatcc atgacttaat ttttttgtta tatccataaa
    36421 atatccttct ttctattttc ttacattatt aaaatttaac atatatacta taatttatta
    36481 aaccttatat gttcaaaact acagtataca aaacatagat atattttatc aaattaagtt
    36541 taaaaatact tcataaatat aatattagtg aaaatttctc ttctaaaaaa ctaaaaatct
    36601 tatatgctta cttaaatacc atatttctta attacaaaaa tgaggttgat tcaaaatata
    36661 gataagcctc ttttttattc aaatgctaaa aatatattta attttataca aaaaaagtgt
    36721 ctcataaact aaaaagttca tcttgagaca ctcccataaa aattttacat aacttgtcca
    36781 ccagtaatat ttatagattg accagtacag tattcagctt cctttgaagc ataaaatgta
    36841 agtatatttg caacatccat aaatctacac cctcttttta aaggtacttt atctatataa
    36901 acttgcttaa cttctgattc aggtattccc aattttactg catattgagg aattaaactt
    36961 tcaaacatgt cagaatcaag caaattacca agcatcagtg catttacagt tatcttatgt
    37021 tctgccaaat ctagtgctaa actttgagta agtcctactc cagcaaattt acctgctgaa
    37081 taacctgaat tatgtttgct tcctactcta cctgattttg aatttatctg tattattcta
    37141 ccctcaatac cttttgctat cataacttta gacacttctc ttgcaaatag aaaataccca
    37201 tttaaattta catccacaat aaatttaaaa tctttgtatc caaaatctgt tattttttta
    37261 cttacagcca ctcctgcatt gtacactaat aaatctattc tatcaaaatc attttcaata
    37321 gctttgatag tactcataac ctgtatctca tctatagcat tacatccata tcctacagat
    37381 ttacaaccaa attccatttc tatttcttta gctacttttt ttgcattatc ttcatttaaa
    37441 tctgcaatag caacatcata acctacttta gctaaatgtt tagataaata ttcacctaaa
    37501 cttcttcctc ctccaacgac taaagctact tttctcattt tcatatcccc tttgtatcat
    37561 attaaaagtt aacttgatta gttaaattga cttttatcta taatttactt ataatatgat
    37621 tagattcgtt ttaaatttta ttttctaatt atttttagta tagtacctac gccaataggt
    37681 gctatttctt tttcttcaag atataaggtc cctccaattg ctccatcttt ttcacctgta
    37741 aacttaaatg ttatatgacc taattctgaa agattttggt ttactaactc accaacagaa
    37801 gtaattttat aatcaacatt atttattgat aatacatcat tcgtaagtat ttcttttact
    37861 aaattatttt cagaatgtat ataacagtaa ttttctaatt cttgaggagc attatctttg
    37921 aaagttacaa acatattatg ttgtaaaaat tcatttgcat tatctcctat tttatttatt
    37981 tgagtactgt atattaattc catatcaatt gaacctctct ctaattattt ataaagtatc
    38041 cttttattta tataacccaa agcttgctaa ccatgctaat agaacggttg gcgcacctgt
    38101 taaaaatcta gaatataaaa ctgatggaac tcctacttga actgtatcag gttcagcttc
    38161 tgcaagacca agacctactg gtataaagtc acaggctgct tgtgagttta ttgcaaacaa
    38221 tgctggtaat gctaaacttg gcggaatatt tccttttcct atttctgtac caaccaatac
    38281 acccactatc tgtgctataa cagctcctgg tccaagaaat ggagacaaca acggaaatga
    38341 acatattatt gataaaacaa ctaaacctcc aacatttccg attaatggag taagtaaatt
    38401 ggctacccaa tttcctatac ctgattgatt tattatgcct ataaggactg caacgaaagc
    38461 cataaaaggc agtatagtat gtattaatgt atctatagta tccctaccag cttgaaaaag
    38521 agtgcttgtc acgttaccta gtgctatacc tatttttgca acaattcctt gactctgttc
    38581 acttatcttc tttttagtat cataagccat atttctttcc tcctactatc taaattataa
    38641 ctgctctaca tttgttggtt ttactcctga aacatatatg tcttctttta taaacattgc
    38701 taatggtcca ctttttcctg ttttcattat atttatagtc ggtattttct tttgaggata
    38761 tataccacat ctcaatgttc caccacaatt tattattaca catgcgattt catcatcttt
    38821 aacaccttgt gaaaatccat ctattaactc acatcctgta agttcagcta tttttactgc
    38881 agtttctggc tttgctcccc cagtcacata tactacctta ttcttctttt ctgttggttc
    38941 tattatcaat ggtccacccc atcctccaga accctttatt attttaactt tgttaaatga
    39001 catataattt ctcctcctct atacactatc tttttattta agtagtttac ttatacctta
    39061 aagtaattac ccaatcttta tatctgaatt taatgctatt ccttgttgct tctctacaaa
    39121 ttttgttgta tagtcagtaa ctacaccttt aataaaattt gcaactatac ccactaacaa
    39181 atatctaact gctaaatctg ctgttgagaa tcccaaagtt gttataccat ttgcaattcc
    39241 tagatagata aatagttcac ctggattaat atgtggaaat aatccattca ttgtatggca
    39301 tgaaaaactt gctgctgcaa agtaactagg tttaaacttt tctggtaaga atcttcccaa
    39361 tgatagtgtc attggatttg caaatacaaa tgtaccaaga actggtagta tcaaatatct
    39421 agtaaatata tttgcagaac atttttttgc aagcctctcg actctatctg taccaataaa
    39481 gttgataatt gcattcattg taactaataa tgctactaaa agtggtacta tatctgttac
    39541 aaaacctaca aattgttgtc cacctgccct aaataaattc ataaaactat ctgcaccact
    39601 cgctaatact tgaaaaaatt gtgtcatatt aactcctcct tatagatata tttttttaaa
    39661 ctacttccat cctacattct tcatcagtac taagattact catatcttca catttattct
    39721 tctcaaatgt tatgtactgt ttgactgcat ctagtattgc ttttttaagt agtttattgt
    39781 aaacagttaa atctgatttt tctatgtact ttaagttttt tcctaccaaa ccttcaaatg
    39841 actttactct tgctactact gtaacaccct gcatttttct agtctctata atcacaccat
    39901 catcatttat aagtatcaac acaattgcac ctgatgaaat tcttcctttc tttctgccta
    39961 ttgccactct tccttttctt tttagttcaa tataattctt attaaaatct ttaatctgta
    40021 aatatccaag gaaaatattc aataaataaa ctacaataaa tgatactata ataaaaatta
    40081 ctgggtccat attattacct cctcgtggta attattttgt aaaattcatc aaatgatttt
    40141 actttagaaa gtttttctac tattttttta tctcttccta tttcaagtac ttcttcatag
    40201 ctttttatta tcagttctgt actacccaca ttcttgtccg gaattatcat caatattatt
    40261 attctaattt cctttgtatc ccaaattact ggattttcta atattccaaa tgccaaataa
    40321 aggttctctt cattaggact aactgagtga ggcaatgcaa tataattatc taatgctgtt
    40381 gaagatttct tttctctttt tagtacattt tctttaaact ctatatcaat aattccttta
    40441 agaactagct tctctaacat ctcttctaaa ttttccatga atgtaccctt attcaatata
    40501 aagaacttat cctcttcaat taatttacct ataaaaggaa tattcttttc aatctttttt
    40561 atagacttaa tatttatact atttttcaaa agtattgcat cttctatctc tttctttata
    40621 ctttcttcat taaataacgc atttactcta aaaattggaa catctaagtc tgtcttgaaa
    40681 tctactgttg taaatactaa atcatagtac tttaataaat ctaaattagc tttagcttct
    40741 atatcagaaa aagtatttac ttctacactc tctccaagta tttttcctat ctttattcta
    40801 atgagttgtg cagtcccaag acctgttcca caaacaacag ctaccctatt tacatttaga
    40861 acttttcttg aatttttttc aaaataactt ccaaaatgca atgctatata tcctatttcg
    40921 tggtcacata ttttcaagtc aaacttttcc tcaattatca ttgcagctat ctttgcaaca
    40981 ctatatggaa atgtatatct ttcctttatt tcttgtaaaa gtggattttt tactcgtatg
    41041 ttgaatctca ttctattaag tgcgaaatac aagtgatatt ctaaattttc tataagcttt
    41101 ttatcttctt taaaatcaat tcctgaggtc tctaataaaa aactagttac ttcatctaca
    41161 acttccttta cactatcatt tatctttata ctgctaagtg ctaactttgt actaggagct
    41221 tttctaccta ttaatggcat tgtcaaaaat atggtttctt tttcatttaa aactatattg
    41281 aatatctttt ccaataaagc tttgagtttt aatcctaaag tgtattcatc tgaacatctt
    41341 attacttcaa atctcttatc tatcttttca aatttataac catttagatt tcttaaagca
    41401 gatattatta tatatctttc aacatctctc aatacctgtt ctgttatgta tagttcttct
    41461 tttttaaata acttttttaa ttcatctcta agacattcaa tatcataatc tttaactaaa
    41521 tttatttgat taacgttttc caaaacatca atataatttt catacaatct gtcaaggact
    41581 agcaacctta tatccatttc ctcaccaact aaaatcatac ctatatttgg tttccttttt
    41641 aattctaaat cgtattcagc taaaattctg tctgcttttt ttaaatcctt tattaatgtt
    41701 gttcttccta tacatatctc ttcagccaaa tcatctatag taattggatt gttagtcata
    41761 gttaaaatat caagaacata atttattctt tcatcaggtg aatttaaatt tataaaattt
    41821 gacagcttta ctctattaaa atttactatc tcaattaatt tactttcatc ttcaactctt
    41881 atactatatg tacctttttc atttttaact attttggcaa taccatcttt taattctcga
    41941 ttaatctggt ttatatagtt tctgatagtc ctagtactga cacctagaac acttgaaaat
    42001 tgttctaaag tatttgtatc ttcttccaac accatttcta aaatcaaaaa aaccctaggg
    42061 tccatataag tcattgacat ctttttctcc cctttgttat cttacatttt ttattataat
    42121 ctaaactata tagataatta atattctctt tttcaaatac tatttgaaaa agaagaacta
    42181 atatacactt tttcacaata gcatggaaaa ttataaatta aagtattaaa ttctactttt
    42241 aaacaaaaac catatattaa attttattta attacatatt tttaatatat tatttcttgt
    42301 atattgaatc tatttataaa ctaattttaa tacactccta acaataatat tatataaaac
    42361 aataaaagcc ttatgctgtt aactattaca gattatctac tatctgtttt gaaaacacat
    42421 caggcttttt aaatattcaa tatattattt tatatatttt ctaattatag ttttgtatac
    42481 tatacgttat tttttctttt tatttgcttt ttctatatta atcttattac cttttatctt
    42541 aatatctttc atcttttcaa tcactgtttt tgcatctttt ttaggtattt caacaaaagt
    42601 atacttatca tatatatcta tagtgcctac tactttacct gggattccaa cttctccagc
    42661 tatagcacca actatatctt ttgcttgtac tctttgattt ctaccaatat tgataaataa
    42721 tctaatcata ccatctttag ctccagtacc accttttcta tctccacgct ctcttctagg
    42781 tttttcttct attatctctt ctttcatttc ttcacctaga gatagtttta caagtgcagc
    42841 agctatatca accattgcat aatcttcatc attacagaaa ttttctaacc actgtagctg
    42901 tttagttaaa tgcccttctt cgatagtctg tttaacttgt gcaaagaaag tacctacttt
    42961 tttctcttca acatcagtta tcgttggtat attatgcttt atcagtttag atttagtgta
    43021 tctttctatg tctttcatct ttctcatttc ttttccaaat acaaaagtaa atgacatacc
    43081 ttctctacca gcacgaccag ttctaccgat tctatgaaca taatactctt catcttgtgg
    43141 taaatcataa ttgaatacac attcaacatc atcaacatct atacctctag ctgcaacatc
    43201 agtagcaaca agtatatcta ttgtaccatt tctaaactta tccattacta tatctctttg
    43261 agtctgcttt aaatcaccat gtaatgcatc tgcaaaatat cctcttgctt gtaagtctcc
    43321 tactaattca tctgcttttc tcttagtgtt acagaaaaca acagataatt tagggtcata
    43381 tacatcaact aatctacata atacttctaa tttatttgat gacctagttt ctatatagta
    43441 ttgctttgta tttgaaactg taagttcttt tctaacaact tttatatgct ctgggtcttt
    43501 ttgatatctc ttagttaatt ccaaaattcc tcttggcata gtagctgaaa agaaagttgt
    43561 ttgtctttct tctggaatct tacttaaaat catttctata tcttctctaa atcccatatc
    43621 tagcatttcg tctgcttcat ctaatataat catttttacg ttatccattt ttaatgtttt
    43681 acgattaata tggtctattg tacgtcctgg agtacctatt acaacttgca caccactctt
    43741 tagagacttt atttgtctat ctattggctg accaccatat ataggtagtg tctttattcc
    43801 gtgcgaatat ttagctagtt ttcttatttc tgttgatact tgtattgcaa gctctcttgt
    43861 tggacaaagt actacagctt gtaaacttct attatttggg tctattgttt ctagtatagg
    43921 tatactaaaa gcagctgttt ttcccgtacc agtttgagcc tgtcctataa cgtctttacc
    43981 tgacaaaatc gcaggtatag actgtgcttg tataggagat ggttcttcaa accccatttc
    44041 agctattgct ttttttattc cctcacttat tggtaaatct tcaaactttg ttatattcat
    44101 atattattcc tctccgttat caattaatct taacctatcc attatatact tttttagaat
    44161 attctgcaat taatattttt aacagtatag ttaaataata tacatgaaat acaaaattga
    44221 tatgtacaga aaatatgtga ataacatcaa tataccttgt attctactaa gtctatttga
    44281 tttaagtgtt ggtattatta ctattaatat caataatatc atgaatggta tatctaattg
    44341 tctattttga gatagtatcg gtatattatt tggtattgct gatatagcta ttactgacac
    44401 tatattcaat atatttgccc ccaaaatatt tcctactgat atttcatgat gattttttct
    44461 tatagctgta attgatgaaa ctatttctgg aagagaagtt ccaagtgcta ttatagtcaa
    44521 acttactata ccttgaggta tatttaaaaa gctagcaatt cttaccccac tctctataag
    44581 gatttgagaa cctattatca tcattatcaa tcccgtagca aaaagtaata gtatttttac
    44641 aatttctaat acggaaaaac ctctataatt tttccctttt ttagtagata tgtctttaat
    44701 agtgttattt ttaatatttc tacttttagt atcagatttt ccaacgacac ttctataatt
    44761 attaaccata taaaagatta atattattat aagtaataac gaatcacctc ttgttataac
    44821 tccatctaaa ctcaataaaa ttaaaactat aacggatact attaatagta aagacttaga
    44881 aaaaaacatt tttttatcta cattaaatgg acttagaaaa acaaccaacc ctaatgctaa
    44941 ccctgtatta catattatag aaccaactgc atttcctaaa ctcatagtag tatgaccatc
    45001 aatagaagca agtagagaca ctgtaaattc aggtaatgtt gttgcaaaac taactatagt
    45061 agctccaagt ataatttctg atatattcgt ttttctacct atctctaccg tacaatttat
    45121 aaagatatct gcgcccttag taattaatag gaaacctact aaaaataata ccactgtgat
    45181 aaacaatata tcacctcccc ctattaaata aatattcagt ttgtgaagat gtatgctttt
    45241 tcttttttcc ataataaaat ttatttattc taaacaaaaa ataaaaaata ttttctcctt
    45301 aattagctat ttatttgttt tattttattt gtatatgggt ataatttcac catattatta
    45361 acatataatc tgttttatac tttaaagcga caatttttta ttttttatgt atacaggata
    45421 c
//
LOCUS       DAMKOJ010000026        45289 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000026 DAMKOJ010000000
VERSION     DAMKOJ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.027"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            36..1553
                     /locus_tag="PC592_001551"
     CDS             36..1553
                     /locus_tag="PC592_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009260080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HDF4055533.1"
                     /translation="MMLRQYAAEHSLNVIDEYIDDGWSGTNFDRPDFQRMIDDIEDGK
                     INCVVTKDLSRLGRNYILTGQYTEIYFPSKGVRYIAVNDNVDTINGENELAPFLNILN
                     EMHARQTSKKVKAAMRTRFANGAHYGAYAPLGYVKDPDKKGHLLIDPETRWIIEKIFD
                     LAVHGRGAASITRILVEEKVPTPGWLNFQRYGTFANIYAGAPEEKAYAWTIAQVKSIL
                     KEETYIGHSVHNKQTNISFKNKKKVRKPKEEWYRVENTHEAIISEDVFRQVQEQICNR
                     RRRQKNGTTQIFSGLVKCADCGWSLAYGMNSQNKNPYAHYHCSKYGQGLHQCSMHYIR
                     YDVLYAYVLSRLQYWSVLAQQDGDKLLKRLLNASDKERNTARKRQTAELKKAEKRKAE
                     VDTLFAKMYEDWSAGRITEYNFNMLSEKYQGEQRELDAKIERLHEAMEVAAQTAVDAE
                     KWIGLMKQYVNPTELTAELLNTLIEKILVHEAVKSEDGSREQEVEIFYRFIGKIE"
     gene            1591..2691
                     /locus_tag="PC592_001552"
                     /pseudo
     CDS             1591..2691
                     /locus_tag="PC592_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(3002..3523)
                     /locus_tag="PC592_001553"
     CDS             complement(3002..3523)
                     /locus_tag="PC592_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF4055534.1"
                     /translation="MKFERLRTSKDKLYYKAMELYKTSFPFHEQRKSSLQAKIMENKE
                     YQFNLIYDKNQFVGIILCWETKSFIYVEHFCIFPEMRNNRYGQKTLELLNKRGKTIIL
                     EIDPPIDELSTRRKKFYERVKYKTNYYKHIHPPYQEKFNGHQLVVMSYPERLSKMEYD
                     KFNQYLKNHVMNF"
     gene            3885..4682
                     /locus_tag="PC592_001554"
     CDS             3885..4682
                     /locus_tag="PC592_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF4055535.1"
                     /translation="MEKREKRIIISSLLSVSILMSLVSIYSILNKEDISLTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGKEGEKKLIYNLTYHDEKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGSKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            4792..5382
                     /locus_tag="PC592_001555"
     CDS             4792..5382
                     /locus_tag="PC592_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDF4055536.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLVRFNEDVVKNSPDIVFIMGGTNDFIAGAGNEVINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNIREDWSCFTDFNIVSQKLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            5447..7144
                     /locus_tag="PC592_001556"
     CDS             5447..7144
                     /locus_tag="PC592_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF4055537.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKIELEKIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETNRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSIIPTPSEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNIPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTIGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYEGLIELYEK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSVKVIDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVGKLK"
     gene            7345..8184
                     /locus_tag="PC592_001557"
     CDS             7345..8184
                     /locus_tag="PC592_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDF4055538.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLIGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIKHE
                     MLK"
     gene            8703..10559
                     /locus_tag="PC592_001558"
     CDS             8703..10559
                     /locus_tag="PC592_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HDF4055539.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYQVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIVGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGESTGKLFKDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIIDNIIYSGYSNKNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVESKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTAKDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKIQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKEDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGVGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    10642..10882
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    10948..11183
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11268..12485
                     /locus_tag="PC592_001559"
     CDS             11268..12485
                     /locus_tag="PC592_001559"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF4055540.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKGKKYSNMITNNIDDIFNKDIDILVEVMGGLEPALSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            12601..13095
                     /locus_tag="PC592_001560"
     CDS             12601..13095
                     /locus_tag="PC592_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055541.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGGSDSEGNRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     QAEKYWDEYSKYNYQGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            13334..14599
                     /gene="hisD"
                     /locus_tag="PC592_001561"
     CDS             13334..14599
                     /gene="hisD"
                     /locus_tag="PC592_001561"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDF4055542.1"
                     /translation="MKRIKTSSMKEKVDEKILREQVSSIIEDIRNNKDIALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIKEFAKAQKSSFENSFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKIKPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSKPVYIAADLLAQCEHDLNARGILLTNSLEIAEEVEKNI
                     ETMLKDLPTKDIAYSSWKNNGEIILVDDMEEAIKISNFYAPEHLEIAVNKCDDIFDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEEAI
                     ESLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(14804..15556)
                     /locus_tag="PC592_001562"
     CDS             complement(14804..15556)
                     /locus_tag="PC592_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4055543.1"
                     /translation="MSYFQYQGNACFYEEYGQGKPIVFLHGNTASSNMFKALMPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDMWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCQGKDWEN
                     VVNLDTKALLQCAKEKRPLFHKELCKLEMPILFIGSKEDEMCRHNLEEEYKQMATFIR
                     KASIHIFSHGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(15674..15943)
                     /locus_tag="PC592_001563"
                     /pseudo
     CDS             complement(15674..15943)
                     /locus_tag="PC592_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16418..17192
                     /locus_tag="PC592_001564"
                     /pseudo
     CDS             16418..17192
                     /locus_tag="PC592_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            17187..17392
                     /locus_tag="PC592_001565"
                     /pseudo
     CDS             17187..17392
                     /locus_tag="PC592_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
     gene            17798..18430
                     /locus_tag="PC592_001566"
     CDS             17798..18430
                     /locus_tag="PC592_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF4055544.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            18841..18933
                     /gene="kdpF"
                     /locus_tag="PC592_001567"
     CDS             18841..18933
                     /gene="kdpF"
                     /locus_tag="PC592_001567"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDF4055545.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            18974..20656
                     /gene="kdpA"
                     /locus_tag="PC592_001568"
     CDS             18974..20656
                     /gene="kdpA"
                     /locus_tag="PC592_001568"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDF4055546.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYSAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGIILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGYMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTAVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAVPAGLEGISNPGF
                     HGLSQVLYEFSSSAANNGSGFEGLGDNTMFWNMTTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            20681..22738
                     /gene="kdpB"
                     /locus_tag="PC592_001569"
     CDS             20681..22738
                     /gene="kdpB"
                     /locus_tag="PC592_001569"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDF4055547.1"
                     /translation="MDTKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRVYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFITVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGIVPEDLEENVNRVAKLGGTPLVVCVDNGIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQSE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            22757..23383
                     /locus_tag="PC592_001570"
     CDS             22757..23383
                     /locus_tag="PC592_001570"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDF4055548.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELRDRVQKDIEQFLKDNPTVKKEDIPTDLLTASGSGLDPNISPDSAKIQIPAV
                     AKASGISESKLQKIVDDNTSKKVFGVLGEDRVNVLKVNVEVARILGLI"
     gene            23620..24528
                     /gene="cysK"
                     /locus_tag="PC592_001571"
     CDS             23620..24528
                     /gene="cysK"
                     /locus_tag="PC592_001571"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDF4055549.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEKRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSIER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIKVVALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEIILVDDEDAFDTVKLLASKEGILVGISSGANIFGAIEM
                     AKRYPDKKIVTVAPDGVDKYMSMGIF"
     gene            24555..25145
                     /gene="cysE"
                     /locus_tag="PC592_001572"
     CDS             24555..25145
                     /gene="cysE"
                     /locus_tag="PC592_001572"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDF4055550.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVDYEYDELDNVYYI"
     gene            25306..25494
                     /locus_tag="PC592_001573"
     CDS             25306..25494
                     /locus_tag="PC592_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF4055551.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMNDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(25548..26417)
                     /locus_tag="PC592_001574"
     CDS             complement(25548..26417)
                     /locus_tag="PC592_001574"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HDF4055552.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEVGISTEDINKLVHEFTLQNGAIPAPLGYNG
                     FPKSVCTSINNEVCHGIPNKDIILKDGDIINVDVSTIFNGYYSDASRMFMVGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAVNSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(26614..27864)
                     /locus_tag="PC592_001575"
     CDS             complement(26614..27864)
                     /locus_tag="PC592_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055553.1"
                     /translation="MIMENNLNTAKRNNTELSQNDSLKVNLQIGVDFTLLSKSLKAFY
                     KKEKDFYCIALAPCNVSSEEANRKISIYDMIKEINILIESITDKNELLSEELFTNNLS
                     EFYDESLDEIYIDLKQAYLYIKKNTNGLNIEDSIEYVFDVDISNDIKAKENPLINFNS
                     LSLVVWSGETKHILQQMNILNLEDIHSYSMENNTNITIYENDNLQYKFDEESEDIKDS
                     NIDIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQALKEKDIKIKLINSNLTDEP
                     EFSDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYTNVHSSKNLELHETA
                     HAIDKNVLNKKSNSEEFMKVFAQERYKLYDPKQIAHAYISKFIEEFFAESFVHYYLDE
                     DSKNTLKENCPLTYDFLEKLELYY"
     gene            28151..28453
                     /locus_tag="PC592_001576"
     CDS             28151..28453
                     /locus_tag="PC592_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF4055554.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGVNSKYTRAKGFK
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPNILINSINNKTDYIIGKEIE"
     regulatory      28555..28647
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            28747..29541
                     /gene="thiD"
                     /locus_tag="PC592_001577"
     CDS             28747..29541
                     /gene="thiD"
                     /locus_tag="PC592_001577"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDF4055555.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTQGVFAVEDLNKNIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVKNLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGKEILQLGPKFVLMKGGHLDGEAVDILIGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNFSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            29565..30350
                     /gene="thiM"
                     /locus_tag="PC592_001578"
     CDS             29565..30350
                     /gene="thiM"
                     /locus_tag="PC592_001578"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDF4055556.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANATLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEDSTDIIRKVAKKLECIVVA
                     TGKIDIITNGKSTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLTM
                     SLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            30373..31005
                     /gene="thiE"
                     /locus_tag="PC592_001579"
     CDS             30373..31005
                     /gene="thiE"
                     /locus_tag="PC592_001579"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF4055557.1"
                     /translation="MIDKESLKKCLRLYLITDSEMLEGRDFYKCIEDAISSGITTVQL
                     REKNTCGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNDKILGVSARTLEEAICAKNDGADYLGIGSIFSTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLDSDGYAIISAILKAEDISKEVEKWTLKI"
     gene            31144..31446
                     /locus_tag="PC592_001580"
     CDS             31144..31446
                     /locus_tag="PC592_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4055558.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMFDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(31512..32261)
                     /locus_tag="PC592_001581"
     CDS             complement(31512..32261)
                     /locus_tag="PC592_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055559.1"
                     /translation="MLNILWRSMKWRFKNPISFIVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIILVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVAILCIVSIFFSVTIESGIGGILLMTVLVFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIENLSGGLKVVVMLNPFTHVINALRSLIFGETVLI
                     EDILPVILLFLILCCASFSLAMWRLKKEMVS"
     gene            complement(32255..33217)
                     /locus_tag="PC592_001582"
     CDS             complement(32255..33217)
                     /locus_tag="PC592_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055560.1"
                     /translation="MLAVEIDNLVKEYKNGVKALNGLSFNVNSGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMIFQS
                     KMYKVKPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRYEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNIIRITFHNTEDIKKYNDAIKGTGLVKFMNVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEGWEC"
     gene            complement(33221..33673)
                     /locus_tag="PC592_001583"
     CDS             complement(33221..33673)
                     /locus_tag="PC592_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF4055561.1"
                     /translation="MSYKIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNGAP
                     FFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHIGSYSNLPKTYE
                     MIFKYIHENNIKIQTPWREVFIKGPGMLVKGKPDNYITEIIFPLKEEE"
     gene            34034..34390
                     /locus_tag="PC592_001584"
     CDS             34034..34390
                     /locus_tag="PC592_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4055562.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVIGELKPGDTIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNHQSSVTIDENILKNLKLELINESLSVFLKDMKA
                     INVTKEEVLKIIEDKY"
     gene            34462..35178
                     /locus_tag="PC592_001585"
     CDS             34462..35178
                     /locus_tag="PC592_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055563.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINTDSGEIRIDGEKINEKIYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKKKSKEMMNIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVIILDEGQIIASFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            35171..35995
                     /locus_tag="PC592_001586"
     CDS             35171..35995
                     /locus_tag="PC592_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055564.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLGLNLFEINKFKNS
                     KFIINLAIGDFGGIFYGIGILSNLGFIQSILFFGMLGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALLTMIYGFLISQIATLFICKYIFNFIFRNVPIINMNFAK
                     DLYYLNLKGIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYILLITLLIIVG
                     LYFSTIYISIITLFRKYYMAIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKISL"
     gene            36006..37205
                     /locus_tag="PC592_001587"
     CDS             36006..37205
                     /locus_tag="PC592_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055565.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDPNELD
                     YININFGYAFNGYVNSYYTINGSNKTKKTELIKLQKDAKNTNNLIDVSSGSDLIAHVG
                     FEMNDDSKDINFVIDEKKEDLEKGVFPSEGDDKAVEYEKLDMNDFTRTRYKVDKSSDN
                     YYANILSSKRYKKYLYVSVLYATSDSSKNNKEYSSTIDIIKINPENKKIQTIKSINLS
                     NYFSKKYQNIDNISVSYASKYEDKMYILVNVLNANTGDKSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKVKLEDNKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYILDN
                     KEKRGIRSIEIDSNKIIVYTSRLNSTLSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            37214..38026
                     /locus_tag="PC592_001588"
     CDS             37214..38026
                     /locus_tag="PC592_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055566.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNAIGFSSFRNIMGYTESWFMFGIIVCICYAFFIWYRDF
                     NGRSKSIYTLIMIPKNRINIYISKLLNILFLVYSYTVVLTISLFITSKLLPRHMLGNV
                     TSYGFVQETIYNLKMLLPYSFEILFVQYIFLLIGFVSVVFTSILINKSIYRVSALISF
                     LFLVLEILVFIISIEFIIPYEYSNVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            38037..39305
                     /locus_tag="PC592_001589"
     CDS             38037..39305
                     /locus_tag="PC592_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055567.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYDEVIISKNGVRNNTNPTSIIRNDYLNIDKKYSDFVNDKG
                     KDLIYKDDLNIGEAYTSVKYDLVQGMNALNDCIKVSNKNLKSGAEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISSSKVNNICILKIDIKNKSYKLLNRFNLVLQNG
                     YQQNINEIKFSIGSKLYLEIVNNQSTNEDIEEHDNYSNFIIYDIEENTFNISDKFMDN
                     LNKEKNANPKEIGLLGKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNKIKLEDYE
                     ILDLKVDYNEASSGIRKVKLLDDKIYSISGIKNNLSGELKGFKGVVDIVGTNPVKFKV
                     FDMKLKKTVYEAELINGDVSLQEKLFFVAN"
     gene            39662..40843
                     /locus_tag="PC592_001590"
     CDS             39662..40843
                     /locus_tag="PC592_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF4055568.1"
                     /translation="MNKKYIKAGNLIDGTGNSTMQNKGIIIDGDTIVEIEDIREDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKVYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVDGNPIENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(40985..41902)
                     /locus_tag="PC592_001591"
     CDS             complement(40985..41902)
                     /locus_tag="PC592_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055569.1"
                     /translation="MENNKCREDFRFTQEYEEDYMNANDRYYENYQVADRYYNYPNKY
                     KEPKMTKCCCKKSMREALELLRYDSLRPFVNFNQFAFISDFFIVGAYLVGIDYSIPPK
                     DNLSGLNGTFERFSACNCDLIDISGQLYYPKPVPLTLGGLVTSIGTIPGVSELVALIE
                     AAVPATIDLGSILNSILDYIIDYIISTVNPLTNVDLASLCNLKAVAFNVTPADYEDFI
                     SSLAYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVLVLGNSNDSRIYFVCVDSIDYIA"
     gene            42155..42949
                     /locus_tag="PC592_001592"
     CDS             42155..42949
                     /locus_tag="PC592_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055570.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKIKTKKEEFFAVNNVS
                     FKVIEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINVSGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEEIEESIENVVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGEIIASGTPQSLKEESGVNNLRDVFIKLARREDI"
     gene            42950..45010
                     /locus_tag="PC592_001593"
     CDS             42950..45010
                     /locus_tag="PC592_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4055571.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKNIKNTSSDKGKIRVLDVDNYK
                     KSLEENKIDAYIKIEEKKSSTSYRIYINSSQENSSNAVKRIETVLDKYKRSTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMTFILVSGGISNQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGIVGIIMTQFIIISLPLLFAYYIKADFKEVFSLKIPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQSMEVAENLNKALFMKDSVLLNLLVIALLPAICEEIFFRGFIFSSF
                     SKSKDKNKSIKLTIICSSVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNGVAVMLNHYTTGNIINLYKFVEVDFSNLNVLEFALILLISLILVMLGARALGRK
                     SLRN"
BASE COUNT        17577 a         5059 c         7671 g        14982 t
ORIGIN      
        1 tgcaaggaga aagcgggagt attcagacac aacgcatgat gctccggcaa tatgccgccg
       61 agcatagcct gaatgtcata gatgaatata tcgacgatgg atggtctgga acgaactttg
      121 acaggccgga ttttcagaga atgattgatg acattgagga cgggaaaatc aactgcgttg
      181 ttacgaagga tttatcccgc ttaggcagaa actacattct gaccggccaa tacacggaaa
      241 tctactttcc cagcaaagga gtccgctata tcgctgtcaa tgacaatgtg gacaccatca
      301 acggagagaa tgagcttgcc ccattcctca acattctgaa tgaaatgcac gcccgccaga
      361 ccagcaaaaa ggtaaaggcg gccatgcgga cacggttcgc aaatggcgca cactatggag
      421 cctatgctcc gcttggctat gtcaaagacc cagataagaa aggccatctt ctgattgacc
      481 cggaaacaag gtggattatc gaaaagattt ttgaccttgc cgttcatggc cggggagccg
      541 ccagcattac acggattttg gtcgaagaaa aagtacctac tcccggctgg ctgaatttcc
      601 agagatacgg cactttcgca aatatctatg ccggagcgcc ggaggaaaaa gcctatgcgt
      661 ggacgatagc gcaggtgaaa agtattctga aagaggaaac ctatatcgga cacagcgtcc
      721 acaataagca gaccaatatt tcattcaaaa acaagaagaa agtacgcaag ccaaaagagg
      781 aatggtatcg tgtggagaac acccacgaag cgattatttc cgaagatgtg ttccgtcaag
      841 tacaggagca gatttgcaac aggcgcagac ggcagaagaa cggcacaaca cagatatttt
      901 ccgggctggt aaaatgtgcg gactgcggct ggtcgctggc ctatggtatg aacagccaga
      961 acaaaaatcc ctatgcccac taccattgta gcaagtacgg gcaaggattg caccagtgtt
     1021 ccatgcacta tatccgctat gatgtgcttt acgcctatgt cctttcccgt ctgcaatact
     1081 ggtctgtgct ggcacagcag gatggggaca aacttctgaa acggctactt aacgccagcg
     1141 acaaggaacg caatactgca aggaagcggc agacagccga actgaaaaag gcggaaaagc
     1201 gcaaagcaga agtagacacc ctgtttgcaa aaatgtatga ggactggtct gccggacgca
     1261 ttacagaata caatttcaat atgctgtccg aaaagtatca gggcgaacag cgagaattgg
     1321 acgcaaaaat tgaacggctt cacgaagcga tggaggtcgc cgcccagaca gcggttgacg
     1381 ctgaaaagtg gataggtctg atgaaacagt atgtcaatcc cacagaattg acggctgaac
     1441 ttctgaatac gctgattgaa aaaatccttg tccatgaagc ggtcaaaagt gaggacggaa
     1501 gccgggaaca ggaagtggaa atcttctacc gctttatcgg caaaatcgaa tgacacatct
     1561 tgagataccc aacaatatct ttaactaagg gaaacgggaa attcttatcc agatatagaa
     1621 ttattgccat tattggcaga tttttttaat gtatctattg ataagctttt aaactacaag
     1681 attgatttaa gtgaagaaga agtgacgaaa atttataaag aattagaatc aatttttgcg
     1741 ggaattgaag ttgatttatc aacagaggaa ccaaaagaag aatgtaagcg agacttggaa
     1801 tatgtaaaaa acctttctaa tatgtatata gaaaagtatc ctaaaagtta tctattaaag
     1861 ttaaaaatat gttcgttgta tcagatgtat tcatataaat ttggcaagaa tgattttaat
     1921 aataacgtaa gagaaacaac aaatatactt gaagatatag taagaaatac agatgatatt
     1981 caaataaaag aaacagcact cattatctta tcaaatgcat attgtatgtt ggaggattat
     2041 gaaaaggcag agctgtactt aaatatgata cataaaccaa taggagatac aagtgtcaat
     2101 ttagctatga tatatttaaa tcaaaataag ctagaagaag cagaaatatt gcttcaaaat
     2161 aaactgttta gtaatgtatt caatttaagt ttggattgta aaggaataat caatgtatat
     2221 aaatatcaat ataaggaatt aaagaaaaaa ttggagtatg gagattctaa taaaaaagca
     2281 atagagaaag aaatggaata tataaaaaat aagttgctag ggtatgcaaa cctctcttta
     2341 gaaattaaaa aaatgattag tgaagataaa ggtgcatttt ttggtatata tatggattat
     2401 atggaattat ctttaacttt tttatttttc aatatgaaag aagaagccaa aaaagcttta
     2461 tatagtctaa aagaaatatt agaaaaatac cctatacatg aaagtttgga tgttagtcag
     2521 atgagatttt ttgacaaagt aaaatctaaa aattcatata ccttcaatat gtatacgaat
     2581 ttattaataa tgtttagtga tgatagctat aatgaactta gaggagaacc aattttcgag
     2641 tctataattg aaaagatttt ggagttggaa aaattattaa aagataaata ataaataaaa
     2701 atctaatata agatttaaag attaattaaa ttaaaaggag atgtgtcaaa acacaaattt
     2761 gaaccatctc ctttattaca taaaaaaaat agaaaagggc ttgttaagaa gtattctaaa
     2821 accattaaat caaatgatta tatcaaaaga atagaaatat attaaaaata aacaaatgaa
     2881 aattaagaag ctgatatatt ttcatcattt taacaaaaaa gagacctatc tctattttga
     2941 gacagcctct tttatgtaat tgttatgaaa ctttgcacaa ctcaatagat aggaactata
     3001 cttagaagtt cattacatga ttctttaaat actgattaaa tttatcatat tccattttag
     3061 ataatctttc tggataagac attacaacta gttgatgacc attaaatttc tcttggtatg
     3121 gtggatgaat atgtttataa taatttgtct tatattttac tctctcatag aatttcttgc
     3181 gacgagttga aagctcatca attggagggt caatttctaa aataatagtt tttcctctct
     3241 tatttagcag ttctaacgtt ttttgtccat atctattatt acgcatttct ggaaaaatac
     3301 agaaatgttc tacataaata aagctttttg tttcccaaca tagaattatg ccaacaaact
     3361 gatttttatc ataaattaaa ttaaattgat attctttatt ttccataatt tttgcttgca
     3421 aagaagattt tctttgttca tgaaatggaa aactagtttt atataattcc atagctttat
     3481 agtataattt atctttgcta gttcttaacc gctcaaattt cattttgttc ctcctaatta
     3541 cgaaaaattc cgatttatat atgaatttat tttatcacag tcagcatttg tatacaatgt
     3601 gttttcagtt gtatattatt tctcaatttt attccactta tgtctacatc tcatgggctg
     3661 aaatataatt gtttattgtg taacctcaaa ctattataca ggttctgatg gcttaaaaac
     3721 agcatactta tagaattttt ttatgtatga aaatgatttt aatagtttta gaagttacaa
     3781 aaaagttaca taaatttgga aagctataat atacatatat aatataaggt taaaactgta
     3841 ataaataatg ttaatttaaa atttgaacat ggaaggagat tattatggag aaaagagaaa
     3901 agaggataat aatatcatct ttattaagtg tatcaatttt aatgagtttg gtaagtatat
     3961 attctatatt aaataaagaa gacataagtt taactgttaa aggtcaagag caaaaagtat
     4021 cttcctttaa gaaaacagtt gaagaacttt tggatgaaca gggtgtaaag tataattctg
     4081 aagataagat taatccaagt ttagatacag agctaaaaga tgatatgaaa ataaaagttg
     4141 ttaaggtaac taaaagtaaa aaagaagaaa ttgaaaaaat tccgtttgat acaaagcatg
     4201 taaatgatag taatttgtta aaaggaaaat ctaaagttta tcaagagggt aaagagggag
     4261 aaaaaaaact aatctataat ttaacttacc atgatgaaaa gttagtcaaa aaagtcttat
     4321 caaaagaagt aatatctaag gagccaacta caaaaattat aaaatatgga actaaagaaa
     4381 aagtactaat agcatcaaga ggagcaaata taagaggaag taaacatatg aaagtggttg
     4441 ctactgcata tgcaggagat acaataacat ctactggtac aactccaaga tggggtgtta
     4501 ttgcagttga tccacgtgta ataccatatg gaacaaaagt atatatacct aagttaggta
     4561 tgacttttgt ggcagaagat tgtggaggtg caattaaagg taatagaata gatattttta
     4621 tgaatagtga aggaaaagcc tcaaattggg gaaggaaaag catagatata tatttacatt
     4681 aaattagtga atagaataac tttacttgaa agataaaaaa gtataaaata tgaattaact
     4741 aaactattag attattctta aaacataaaa atatatctaa ggggggataa gatgaaaata
     4801 gtctgtttag gagacagttt aacatatgga tttggagtat cacgaagtaa ttcatggaca
     4861 aacattgtaa ataaagagac tcgattagaa atagtaaata agggtataaa tggtgataca
     4921 acaagtggta tgttagttag gttcaatgaa gatgttgtaa aaaactctcc tgatatagtt
     4981 tttataatgg gtggtaccaa tgattttatt gcgggtgcag gaaatgaagt tattaattct
     5041 aatataatgg ctatggtaca tcagtcatat tcaaaaaata ttatacctat aataggtata
     5101 ccattaaaac cagatattcc aaatattagg gaagattgga gttgttttac tgatttcaat
     5161 atagtatctc aaaagttaga atcatatagc tattggataa aaaaattctg tatgacattt
     5221 aatactaatt tcgtagattt ttattcagaa tataataaaa atatggaact agaaggatat
     5281 aaaaaattat attttgatgg gttacatcca actaaggaag gtcatagaat aatggcagac
     5341 atttttatta attcaattaa taagtatata gaagagttat agttacatca aaatacttgt
     5401 ttatgtgtca gtttcaataa atacatacag tagagagggg tttattatgg attatactaa
     5461 aacttatgaa gagtggataa agggttcata ttttgatgaa gatacaaaga tagagttgga
     5521 gaaaataaaa aataatgaaa aagagataga ggatagattc tataaggatt tagaatttgg
     5581 aactgcgggt cttagaggaa taattgaagc aggaacgaat agaataaata agtacacagt
     5641 tagaagagct acttttggat tggcaaacta tatattagaa aacacaacaa aagaagaaac
     5701 aaatagagga gtagtaatag ctcatgacaa tagacacaag tctagacaat tctgtataga
     5761 atctgcaaat actttggcag catgtggtat aaaagcatat atatttgata gtttgagaac
     5821 tactccagaa ttatcttttg ctgttagaag cttaaatgca atcgctggta tagtcataac
     5881 agcaagtcat aatcctccag aatataatgg atataaggta tactgggaag atggagcaca
     5941 agttatgcca gagattgcaa atgcaataac agagaaagta aatagtatac atgattatag
     6001 tataatacca accccaagtg aagctaataa aaatttagta gttttattgg atgaatcaca
     6061 agatactaaa tttatagaag cagtaaaaag tcaaattata agaaaagatt tagttaaaaa
     6121 tgtaggtaaa agcttcaaga tagtttatac acctctttgt ggaaccggaa atattccaat
     6181 aagaagagca ttaaaagaag tgggttttga aaatataatt gtagttccag aggaagaaaa
     6241 tccagaccca aattttgcag ggcttgatta tccaaatcca gaagagaaaa aagctttaaa
     6301 tagaggtata ttactcgcaa aagaaaaagg agcagacctt gtaatagcaa ctgacccaga
     6361 ttgtgataga gtaggtgtag cagtaaaaac tactataggt gagtatgctt tacttacagg
     6421 aaatcaaatt ggtggtatgc taacacatta tataatagaa ggattaaaag aaaataataa
     6481 attaaaagaa aatcctacaa taataaaaac catagttact tcagaatttg gagcagatat
     6541 agctaaagca aataatgttg atgtattaaa tgttcttaca ggttttaaat ttattggtga
     6601 aaaaataaaa ttatttgaac aaaataaaaa tagaagttat gtatttggat atgaagaaag
     6661 ttatggttac ttagttggta ctcatgcgag agataaagat ggtgtagttt cttcgttatt
     6721 aatatctgaa atggcagcct tttactattc aaaaggtatg agtttatatg aaggtttaat
     6781 agaactttat gaaaaatatg gattttttaa agaacagacc atatccttga ctttaaaagg
     6841 tatagaaggt gtagaaaaga taaaagaaat aatatcttac tttagggaaa atcaaattga
     6901 ttatataaat agtgttaaag tcattgataa aaaagattat aaaaatggta tagataatct
     6961 tcctaaatct gatgttttaa aatacttttt ggaagatgaa tcttgggtag ctataagacc
     7021 atctggaaca gaaccaaaac ttaaatttta catagctgta aaaggagcta gtgatattga
     7081 agcagataaa aagattcaag gtttaaaaaa atatatagat gacatggtcg gaaaattaaa
     7141 ataaaatatt attattttat aataatattt atttagctga aaattataat ttactttcat
     7201 tgattagaat atgtaaatgt tagtagaatt gttattttca gcttttattt gtgttatttt
     7261 tacttaaata attatattat agtatgaatc tgagtataat taatattgta taatgaaatt
     7321 aatttgatag aaaaggggat atttatgttt ggtatagata agaaattgat tgaatatata
     7381 attgcaaaat ccaattacag tgaactaagt tcaaagtcag cagaagtatc tttcttctta
     7441 atgttgtcca tatttccttt tttgatattt acaataagtt ctatcgctta tataccaatt
     7501 cttcatttaa ataagtatat agctttgttt agaaatatga tgccagaagg agcttttgcc
     7561 gtattatctt caatcatagt ttctgcaata gacaatagaa atctgaaatt tttagcggtc
     7621 agttttgttc ttactatgtg gacattttca agagcagtaa aagcccttat taaaggaatg
     7681 aatagagctt ataaagttaa agaaactagg tcttttttta aaattttatc tatatcattt
     7741 ttatttacaa taatgctttt ggttcttatt tttttatcta tgatatttct agtttatggg
     7801 gaaaaaatag gttattttat ttttaatctc ataggactag atgagatatt tataaaaata
     7861 tgggatattc taagatacac tgtaggtata ataacaataa tagtgatatt tacactttta
     7921 tataaataca ctccaaataa aaagctaact attaaagaat ctgcaccagg tgctattttt
     7981 gctacttttg cttggttttt agtatcattt ttatattctt attatacaaa ttactatgct
     8041 aactatgaag taatctacgg aagtatagct gaaataattg tacttatgac ctggatgtat
     8101 tttagtagtt ggtctatcgt tattggttat gaagtaaatt caagattgta ttttagaaag
     8161 ataaaacatg aaatgttaaa gtaaagcatt aaaataaagg atattattta atattataaa
     8221 tgtaattgaa ttaataaaaa atattgacat ttaagttaaa aagtctagaa tttttctggg
     8281 ctttttttat ttttagtaca acttgacaaa ctttatttaa tgggatagtt ttaatttata
     8341 atcatctttg aaaagatgac tattgataag caagagatga aattggtaaa agtataaaaa
     8401 aatatactaa ataaagatta tagtcctaat gagttaatgt ctgtgttttc aaataatgca
     8461 gtatttagtc atgtgttttt atatgcgcct gtattcctaa ttaccaatat atattagaat
     8521 aagctactgt aattagattt agaaaaaagc gacataaata attataaaca aataataaat
     8581 tacataaaat taaatttatt cacaagtata tcttataaaa tatgttataa ttaatagaaa
     8641 attgtcatat aattacttaa gaagtattat tataaataac attgagaggt agtggttaga
     8701 atatggatac ccataataaa tatgtaaatt ttataaaaaa tatacctgta ccttttttat
     8761 attgtagaat tgtaaagaga caagaagata tagaatatca agtagagtat ataagtaagg
     8821 gtatgggcaa agtattacaa ttagaagaag gtatttgtga taaaaatata ttagatgtat
     8881 tgcctgtatt taaatctaaa aaatatttca aagagttgtt ctcaaatgaa gtggattgta
     8941 taaaaaggta cattccaaca cttaaaaact ggataaatat aaaaaaacag atagtagggg
     9001 attcatacat aattttgtat tttggtaaaa ttgtatttga ttatagacag ataatcgatt
     9061 cttttgataa aaaggaaaaa gtagcttata ttaaagatga agaaggcata tatatagatt
     9121 gcagtgaaaa tttaatacca atattaaata ataacattaa aacaacaaaa gatatctttg
     9181 gtaaaaatga tatagaagta tggggagaga gtacaggaaa attatttaaa gatgattata
     9241 gagaaggcgt atctagcaaa aaaagatttt tacaaaatct ttttgaatat gaagaaacat
     9301 ttttcatggt tgaaaaatat tttttgtatg acgaagatga acttttaggt actataggga
     9361 taatagacaa tataatatat agtggttaca gtaataaaaa ttataactca aaagacttaa
     9421 tgaagatgat agagcactca attccagaga atatgtttta taaagatgtg tatggaaatt
     9481 atattggatt taattcaggt tttttaaatt tagcttgtat gaataaagaa gaattattag
     9541 gaaagaatag ttataaaata tcagaagaag aagctttaat agataagata tttgaaagtg
     9601 ataagggtgt agttgaaagt aaaaaagtag ttacatttga gttaaatata agtatgaatg
     9661 atgaaaacaa gtgtattgag attacaaaaa ggccattttt tgatagctat ggaagtgtta
     9721 ttggaataat tggaacagca aaggatataa gtagaagaaa aagattagaa gaggaaatgg
     9781 ataaaactag gatggaattt tttgcaaatt tatcccatga acttagaaca cctataaatt
     9841 taatatcatc ttcattacaa gtgatagaaa aaaaagaagc agacttaata gaatcaaatg
     9901 atactttaaa aagaaatcta ggcataataa aacaaaatgg aaatagaata cttaggttag
     9961 taaataatgt tatagacttt acaaaaattc agtcaggata tttagatttt aaaccagaag
    10021 aatctgatat aattgcattt atagaagaga tatgtatgtc tgtagccgac tttgcaagtc
    10081 aaaataatat acaacttaca tttgatacag aaatagaaga attttcaatg ctatttgatt
    10141 cagaaaaatt ggaaagaata atattaaatt tactttctaa cggaattaag tataataagg
    10201 aagatggaaa aataaacata tttttatatg tgaaggataa tgtatttaat atgaaaatat
    10261 ctgatagtgg tataggtata ccaaaagaaa aaatagataa aatatttaat aggtttgaac
    10321 agattgacaa tgaactttcc tacagagtta aaggaagtgg tattggactt tcattagtga
    10381 aatctttggt tgagttgcat gagggaagta tatctttaaa aagtcaactt ggtgttggaa
    10441 gtgaatttat agtttcatta cctgttagaa gtaaaaataa tattgaaaaa tacaatcata
    10501 aaagagaaat cagtaatgaa ctaagtaaaa aattagaaat agaattttcg gatttataag
    10561 tttaagtata aaaaataaaa ttttaaaaaa gtattgacaa ttgatttaga agggtttaaa
    10621 ataaattaca acataataaa taaaaaagcg atgaatagga agagtaaatc taattcgatt
    10681 gccagagaga agagtccatt ggctggaaga ctttttaaat tagagggatt gaaaactacc
    10741 taggagctac tttctgaagt tatctacatc agtagatttt agtaagaata gtcgttaact
    10801 gcgttaaagt gtaaagtgag ttttcatgat atatgaaaac taaattaggt ggaaccgcgg
    10861 gaataatact ctcgtcctta tgttataagg atgagagttt tttgttattt aaaaatataa
    10921 acagtaatca taataattat agaaaatata aaagcgatga ataggaagag taaatttaat
    10981 tcgactatca gagaggaaag ttcgcaggct gaaagacttt ctaagtttga gaaattgaaa
    11041 actacctagg agctgtggtc tgaagttact ttaaaaagtt ttagtaagac taaccgttaa
    11101 ctgcgttaaa gtgtaaagtg gattttatca attaatgata aaatcaaatt gggtggaacc
    11161 gcgagtatag actcgtccct ttatataggg atgagtctat ttttagtgca ataaaagagt
    11221 gaaaataaaa aaaaatcgga aaattataaa tttaggagga aaataaaatg gagaataaag
    11281 tgaaaattgg agtactagga tatggagttg taggaagtgg acttatagat ataatagata
    11341 acaataaaga aaaaagaaac atagaaatag ttgggattct agttaataat ttggaaaaac
    11401 ataagggtaa aaaatattct aatatgataa ctaataatat agatgatata tttaataaag
    11461 atatagatat acttgttgaa gttatgggtg gtttagaacc agcattatct tatataaaaa
    11521 aagcattaaa caataaaatt catgttgtta cagcaaataa agatttgttg gctgaatgtg
    11581 gagatgagct tgcaaaatta gcaagtgaaa ataaagtaag cattaaattt gaagcttcag
    11641 ttgcaggagg tataccagta ttaaaaccaa taatagaatc actagaagga aataatatag
    11701 atagtataaa tgcaatttta aatggaacta ctaatttcat attatctaaa atgtatgatg
    11761 agaatctatc ttatgatatg gcgttaagac aagctcaaga attaggtttt gctgaagcaa
    11821 atccagagtc agatgtatta gggtatgatg ctgctagaaa actatcaata ttatcaactc
    11881 tagcttatga caatagagta tattggaaag atgtgtattt agaaggaatt acagatatag
    11941 atgaaaaaga tattgaatac gcaaaaaaat taaattgtaa aataaaattg attggtcaaa
    12001 gtaagtatga aaatgataaa gtaagtgctt ttgttagacc tgttttagta gaaaaagata
    12061 atatacttgc tagaatagac aatgagttca atgctgtcat agtgaatgga gattcagtag
    12121 gagaagtttc ttttgtaggt aaaggagctg gaagtttagc aacaggaagt gcagtttact
    12181 cagatgttat agatataata gataatagag tttcaagtat agattctttt actaaagata
    12241 aaatacaagt taataaaata gttagagaaa agtgtggagc acttcttaga tttaaaaaat
    12301 gtaataaaga tgaaatttta aatatagttg agaattgttt agttaaattt gatattttaa
    12361 atgatgatga tgaacttgct attatggttt atgctgattc tgaatatgaa ataaataaca
    12421 gtttatgtct aataaaagat aaaggatatt gcgaaaaaat gaataaaatg ttgaaaataa
    12481 gttaaaaaag aaaaaatata agtttatatg taacatattt tgacgatttt aatactatat
    12541 agtatgagat gaaacaaaac atctcataaa aaaattaaaa ttaaagggga gatatgttat
    12601 atggaaaata aaaaatatgc aaatggtggt tattcagaag attggtatga aagaggagaa
    12661 tctacagcta agtggttcca aaatgataga gaagaatatg aaagagcagc atacgatgaa
    12721 gatagagaaa gaagaggttc aaactgtgga ggttcagatt cagaaggaaa tagacctaga
    12781 aactgtgaaa gatttagaag agaagctgag ataagagaaa gagaagcaag agaagcattt
    12841 tgtgaatctt cagagagaaa gaaagaagca ttagcatatg aatgtgaagc tagaaaatta
    12901 tgggaacaag cagaaaaata ctgggatgaa tattcaaaat acaactatca aggaatcgaa
    12961 tatttagcag aagctgctag attatttgat gaaggtatgg aatgtgaagc tagaagaaat
    13021 ggaaataatg gaggaaacaa taataattgt tgccacaaat gccataaatg taattgtaac
    13081 tgctgtagaa aataaaaaaa ttcattgaca aatcaatagt taaaatatat catattatgt
    13141 ataataaaga gaaaattcag aaaaaaataa tgattataag aaatataagt atatttatta
    13201 gacaaatagt gctcagttag tgaggtgagt acaatatgat taaactccca tcctctagct
    13261 cttgatagag ggtgggagtt tttattattg atatattaaa tgaggataat attgtaaaat
    13321 taggaggtaa aaaatgaaac gtattaaaac atcaagtatg aaagaaaagg tagatgaaaa
    13381 gatattaaga gagcaagtaa gttctataat agaagatata agaaataata aagatattgc
    13441 acttaaaaaa tacaatgaga agtttgatag aaatacaaga gatgaattta gaattactaa
    13501 agaagaaata aaggaagctt ataagcatgt agatgacgaa tttataaata acttaaaaat
    13561 tgctgccaaa aatataaaag aatttgctaa agctcaaaaa tcaagttttg aaaattcttt
    13621 tgaaaaagaa atttatccag gtgtaattct aggtcaaaca aatattccaa tagagtcatg
    13681 tcttgcatat gttccaggag gtcagtatcc attgttttca acagctctta tgcttataat
    13741 acctgcaaaa gtagcaggag taaaaagaat agtggcatgt tcaccaacta tgaaaaatac
    13801 tgaaaagata aatcctaaaa ccttggtagc tatggatata gcaggtgctg atgagatata
    13861 tgcaactgga ggagttcaag ctatagcagc atttacatat ggaacagaaa agattaaacc
    13921 ggttgacata attgtaggcc caggaaataa gtttgtaact gaagctaaaa gacaatgtta
    13981 tggacaagta ggaattgact ttgtcgctgg accaagtgaa gttcttataa tagctgatga
    14041 aacttcaaag ccagtttata ttgcagcaga tttattagca caatgtgagc atgatttaaa
    14101 tgcaagaggt atattattga caaatagctt agaaatagca gaagaagttg aaaaaaatat
    14161 agaaactatg ctaaaagatt tgccaacaaa agatatagca tatagttcat ggaaaaataa
    14221 tggagagata attctggttg atgatatgga agaagccatt aaaataagta atttttatgc
    14281 accagaacat ttagaaattg cagtaaataa gtgtgatgat atttttgaca gattaactaa
    14341 ctatggttct ttatttattg gaaatctttc tgctgaggta tttggtgact atgtttcagg
    14401 taccaatcat acattaccaa cgcttaaagc atcaagatat actggtggtg tttgggttgg
    14461 aacttttatc aaaacttgca caaagcagat atttaatgaa gaagctatag aatcattagc
    14521 acctgtagct gaaaagttgg caaaagaaga gggattatat gcacatgcaa aggcagctga
    14581 ggttagattt aaaaagtagt aaaaaattct attttcgtca gtcgagattt agtattagac
    14641 tgagataagg aaaacgccga gaacatgaat aaatactata ttttgtgggt aatcggcgtt
    14701 tcttttatat ctgtatatga taggataata ctacctgtgt gtttaaatga taacttgata
    14761 tttcttttct aaataatgtt tatgaaatag ttaatatttt tagttaatac ttgaaaaaaa
    14821 cttttgctaa ctgtgcaaat tcatctgcat ttgtcaatat agctgggtgt cctccatgac
    14881 taaaaatgtg aatacttgct tttcgaataa aagttgccat ttgtttgtac tcttcttcaa
    14941 gattgtgacg acacatttcg tcttccttac ttcctataaa caaaattggc atttctaatt
    15001 tacacaattc tttatgaaac aaaggacgtt tctcctttgc acattgcaat agagcttttg
    15061 tatcaagatt aacaacattt tcccaatctt ttccctgaca ccattcatag aattttcgtg
    15121 cttgaatatc ttgctttgat ttttcccttc cagtgattag attatctatg aagttatcat
    15181 taagagtacg cccatcaaag ctatctgcta taattgcttc aactaaatcg ggacgttcta
    15241 atccagtatt aacagctgcc catgctcctc cacttgttcc aattaagcca actttaccac
    15301 aattcaaatg ttcaatcagt gctatcgtct gtaaggcttc atcatgccac atgtcaggag
    15361 aaaattgaga aactctatcc gactgtccat tacctaaaaa atcaattaag atacatctaa
    15421 agttttctac atataatggc ataagtgctt taaacatatt agaagaagca gtattaccat
    15481 gcaggaaaac tatcggttta ccttgtccat attcttcata aaaacaagca ttaccttgat
    15541 actgaaaata tgacatatat tgtcctcctt tttatttgtt aagttaatta taacaatata
    15601 ggtatgaatg aaaaacctca tgttctttct tagaataaaa atgtgccacg cgtaaatcgt
    15661 gacacatctc taattataaa ttttgctgtt taagtattct ttgtatgctt ttctctgtca
    15721 aaaagtattt ctctgataac tgcttgatgc tcattcattt ttggaagttt atacagattt
    15781 gagaattacg agaagctaag acttgtttgg tgtttgtgtt ttccccccaa tgctttttgt
    15841 gctcttgctt tttgggaata taaatcactt taccatctat atattcttgc acttgctcaa
    15901 tcagttcttt aggcagtaag tcaatcgaat tttgatagct cattttgcac ctcctaaata
    15961 attgctcttt aggattagca aaggctactg ctactcataa ttaaaaataa aattttgtta
    16021 ttatgtacaa tagcctttgc tatgcacaag ttccaattcc cataaactca atactccttt
    16081 ctgatttaaa aaattcatct gaacattgat ttcgttttta aaatagagtt caatgacaaa
    16141 tttacatttc tattatatat attcaggtag ctaattgcaa ctgtctttgt atgagggaat
    16201 tttattatag tcaatactat aatatgtatt tatatcatca aattaatatg aacagttgaa
    16261 aggaacatga ataataaaac ttagcaggaa gaataattat aaagcagaca atagagaaat
    16321 ttgattctaa ggtttttttg aaaattcatt aacaaattta acttgtaaat attatactaa
    16381 acttaataaa taaagtttat aaagtaagga gttgtctatg aaaaatatag ttggaaaatc
    16441 acaaacgata aaaaaagtaa atgaagactt aataaaaaat attataaaaa atgaaggtcc
    16501 tataacaaaa ctagaaattt caagcattac tgaattgagt ttagctacag ttaataagat
    16561 tgtagagcag ttagctttaa aaaatgaggt taaagtaagt ggactaagtg aatctactgg
    16621 aggaagaaga gctcaattat ttgaaataaa tgcaaactta gaacacataa tagctttata
    16681 ctattataga aattattgta taggggtagt tgccaattta ttaggtgaaa taatttatca
    16741 agaaaaattt aatataagaa tggatacgta ttaaaacgct aaccaaaata ctttttttgt
    16801 tatagatact ttaataaaaa aaagaaaaag gaaataatat aagagccatt ggaattggcg
    16861 tcccaggagt tgtaaaaaaa ggtatagtta aaaatatacc aactataaaa agttgggaag
    16921 gtataaattt agaaaattta ataaagagta aatacaatac taaattattt atagaaaatg
    16981 atacaaatat tactaccatt gggatttatc aaaaacagta taaagaaaaa tataaaaata
    17041 tggctcttat gtatctagaa aatggtattg gttcaggtat agttataaat gacgaattat
    17101 atttaggttc tacaaatttt gctggagaat taaattatct aaatatagaa tttggtaagt
    17161 ataactctaa taacttaaat cttgaagagt atatgtatct ggtatatctg gttgtgattc
    17221 tcctaatgac tataagatta taatggatga aatattaaaa attgggatta acaaagaaaa
    17281 aatatattta gaaaatgatg cagttttagc tttttatgca caagctgatt cacatggttt
    17341 agtaattgtg gctgggacag gttcaattat attaggaatt aaagaagatg gaggataata
    17401 tttcagagtt caagggtgaa tggtaaattg tcatagataa taaataaaat tttcagagtt
    17461 actttatata gtttctaaag taactctttt ttaaattgaa tttagtgata aattattgaa
    17521 tagtatttct aaacaaataa aaaattaata taaacaaaga cttaattata ctaaattata
    17581 agtcaaacta atataaactt atataaaaaa ggaaaacgtc taaagtattg gaattactgt
    17641 gatttaggta tggtattaaa aaaacataaa aaaacataaa aaaattgttg aaaaaactat
    17701 aaaaattttg tataattaaa gatttgaaaa gtgcggtata caaagccaat tcttttgtat
    17761 ataatatata taaattcaga aaaaggaagg gatatgtatg gccaggcggt tatttttaga
    17821 aaggattgga cttatatttt taggttcagc aatattagca tttggagttt ataattttta
    17881 ttatttaaac aacataacag aaggtggagt gttaggtatt ttactactgt taaaaaattt
    17941 attcaatata caaccagcaa tagcaaatgt tgtaatagat ggtttactac ttttagtagg
    18001 atataaattt ttcggtaaaa aattccttat atattcaata gtagcttcta taactttttc
    18061 agtgttatat gacttatttg aagctatagg acctctagta ccacaatcac aaaatatgct
    18121 tttatcaact attttggcag gtgtaactgt tggaactggt gtaggtatag tagtaaaagc
    18181 aggttgtgca tcaggaggag acgatgcttt agcattagta atttctaaga ctacatcttt
    18241 gaacataggg caagtttatt tagcaacaga tgttattgta ttgttgttat cattatttta
    18301 tctatcagct tttgatatat tttactcttt gattgctgtt acaattagtg ggaaggtaat
    18361 tgattttatt tattatcatg gtaaaagttt ggatatggat ataagtaatg atatagttcc
    18421 agaatgttaa tataaattaa ataattttat attttattag gggtggcaag tttgccacct
    18481 tttttgtgtc taaatattta cataaagtat aacctcatct aggtttttat aaatttcaaa
    18541 tataaaatta tgttgaaatg actaggaata cgattactag aggtgctttt taaaaaccca
    18601 attttatatt tatgaaatac taatcattaa tggatgtttc ttaatcctat ctttatacct
    18661 aaaatgataa gataaatgaa gtagcaatac aaaactaaaa tttgtaaaag agattaaagt
    18721 aaatggagga gctaagatgt tggatatagt tatgatagca ttgttattca taggatttgt
    18781 ttccatgaag ttacttgctg attggtgtgg aaaacaaact gaaaaaaaat aatgtaatgt
    18841 atggagggat tacctatgtg gtttctggca gttgtaatta taatgttaat aatatatttg
    18901 gtatatgcgc ttattaatcc tgaaaaattt taaacagtat aagactaata agtaagttga
    18961 attgggggga acgattttta tggtgcagat agtaatagtg ttagcgattt ttatgatttt
    19021 agtaatacct atgggcaagt atttatatca tatagctact aatcaaaaaa catttggaga
    19081 tagactattt gataaagtgg acaattttat atataaagta tgtagtatag ataagaaaaa
    19141 agaaatgaac tggaaacagt atgccttagc tttattattt acaaatgcag ttatggtatt
    19201 tataggatat atcatactta gaactcagag tatgcatatt tttaatccaa gtggaattaa
    19261 aagtatggaa caaggactat catttaatac aataataagt tttatgacaa atacaaatct
    19321 tcaacattat tcaggtgaat caggactttc atactttagt cagatgacag tgataatata
    19381 tatgatgttt acatcagcag caacaggata ttcagctgct atggcatttg taagagggtt
    19441 ggttggtaaa aagaaaacat tgggaaattt ttatgtagat ttaattagga taacaacaag
    19501 agtactttta ccaggagctt taattattgg gattatatta gttacacaag gagtaccaca
    19561 aacttttgct gggacagaaa cggtgactac tatagaagga aaacttcaag atatagctag
    19621 aggtcctgta gcggctcttg aatcaataaa acatttagga acaaatggtg gtggattctt
    19681 tggttcaaat tcatcacacc catttgaaaa tccaacaata atatcaaata tagtagaaat
    19741 attatctatg atgatattac caggagcttg tgttgttgca tttggttata tgataaagaa
    19801 taaaaaacaa ggttgggttg tgtttggtgc aatgtcaatc atatttttaa taggtttagt
    19861 agtttgtttt aaagcagaaa gtgcaggaaa tcctatttta tcacaattag ggcttaatca
    19921 aagtatggga agtatggaag gtaaggaagt tagatttggt atagcacaat catcattatt
    19981 cacagcagtg actacttcat ttacaacagg tacagttaat aatatgcatg atacactaac
    20041 tcctttagga ggattagtac cacttttaaa tatgatgtta aatgtagtct ttggtggtaa
    20101 aggcgtaggt cttatgaata tgttgatgta cgctataata gcagtattcc tatgtggatt
    20161 aatggtagga agaacaccag agtttttaac taagaaaatc gaaggaaaag aaatgaagct
    20221 tattgcttta cttattatat tacatccact tttaatacta atgttctctg ggctttcggt
    20281 agcagtacca gcagggcttg aaggaatttc aaatcctgga ttccatggat tatcacaagt
    20341 attgtatgaa ttttcatctt cagcagctaa taatggttca ggatttgaag gtctaggaga
    20401 taacactatg ttttggaata tgacaacagg tatagttatg ttctttggaa gatatgtgtc
    20461 tattatagta ttactagcaa tatcaagttt gttagcatct aaaaaagctg taaatgaaag
    20521 tataggaaca cttagaacgg ataattttac atttacaata gttttagtac ttgttgtttt
    20581 aattgttggt gctttaacat ttttcccagc cttagcgctt ggacctattt cggagcatct
    20641 agtgttatgg cactaaaaaa ttgggaggga gtaaagtttt atggatacta aaaaaacaaa
    20701 gtttattaca aaagatattt tcaaaacttc cattatagaa gcttttaaaa aattaaatcc
    20761 taaatatatg atgaaaaatc cagttatgtt tgttgtagaa attggattta tagtaacatt
    20821 gatactcaca atagtaccta gtttgtttgg tgatgaaggc aataatttaa gagtttataa
    20881 tgggattgta acaataatct tatttataac agttcttttt gcaaattttg ctgaggctgt
    20941 agctgaagga agaggtaaag ctcaagcaga tacacttaag aaaactagaa aagatacagt
    21001 agcaagggtt atagatacgt taggaaatga aaaaatgata agtgcaagtg agctaaaact
    21061 tggtgatatc gttttagtaa atgcaggaga agttatccca aatgatggag aagttataga
    21121 gggtatagct tctgtggatg agtcagcaat aactggagaa tctgcacctg tcatgagaga
    21181 atctggtgga gattttgcat ctgttacagg tggtactaca gtggtcagtg actggctaaa
    21241 aataagaata acaacaaaac caggagaatc attcttagac aaaatgatag ctcttgtaga
    21301 aggtgcttca agacaaaaaa cgccaaatga gattgcttta aatactttgt tagtagggtt
    21361 aacacttata tttatggttg ttttaatatc tctttatcca atggcaaatt atgcaggtgt
    21421 aaagattcca atttctacta tgatagctct tttggtatgt ttaataccaa ctactatagg
    21481 tggattgttg tcagctattg gtattgcagg tatggatagg gtaactagat ttaatgtaat
    21541 tgcaatgtca ggaaaagcag tagaagcttg tggagacgtt gatactatga ttttggataa
    21601 gacaggtacg attacttatg ggaatagact tgcatcagaa tttataacag ttggaaacgc
    21661 agattcaaaa gacttaataa attattctgt tatgtgttca ttaaaagatg atacgccaga
    21721 aggaaaatct atagttgatt taggcatgaa attaggctca acaggtaaga caaaagaggc
    21781 agaggaagct gagtttgtag aattttctgc acagactaga atgagtggta ttaacctagc
    21841 tgatggtaga gctataagaa aaggtgctta tgatagcata ataaaaagag taaaagaatc
    21901 tggtggtata gtaccagaag atttagaaga aaatgtaaat cgagtagcta aactaggagg
    21961 aacaccttta gtagtgtgtg tagataatgg gatatatgga attatctact taaaggatac
    22021 agtaaaatca gggcttgtag aaagatttgc tagacttcgt gagataggaa taaaaacaat
    22081 aatgtgtaca ggagacaatc ctttaacagc agctacaatt gcaagagaag ctggagtaga
    22141 tggatttatt gcagagtgta agccagaaga taaaatagat gctataaaga aagaacaatc
    22201 tgaaggtaaa atagttgcaa tgacaggtga tggaacaaat gatgctcctg cacttgctca
    22261 ggcagatgta ggtcttgcaa tgaatagtgg tacaacatct gcaaaagaag cagcaaacat
    22321 ggtagattta gattcagacc caactaagat attggaagtt gttgaaatag gaaaacagct
    22381 tctaataact cgtggagctt tgacgacatt tagtatagca aatgacgttg caaaatattt
    22441 tgcgattata ccagctatat tcactcttgc aatacctcaa atggagatat taaatgtaat
    22501 gaaactttct acatcattta gtgcgatatt atcagcttta atattcaatg ctataattat
    22561 cccatgttta atacctcttg caatgaaggg agtaaaatat agacctatga aatcacaagc
    22621 tatgttaatg agaaatatgc ttatatttgg tcttggtgga gttatagtac catttttagg
    22681 aataaaatta attgatttat tgattacacc tttagtaatg gttcttaatt taggttaata
    22741 aatggaggat ataaaaatga aaacattaaa gccagcatta cttgtaagta ttgtattgtt
    22801 agttgtttgt ggacttgtgt atccacttgt tttgacaggt gtaagtcaag ttgcattcaa
    22861 agataaagct aatggaagta tgatagaagt aaatggtgta aaggtaggtt cagaacttat
    22921 tggtcaaagc tttacagatg caagattctt taaaggaaga gtttcatcag taaactataa
    22981 tacttataca aaagaagatt tagtaccaga taaagatgga aatacatctt atggaggtgt
    23041 atcatcaggg tcttttaatt atggagctac aaatccagaa cttcgtgata gagtgcaaaa
    23101 agatatagaa cagtttctaa aggataatcc aactgtcaaa aaagaagata taccaacaga
    23161 tttgcttaca gcatcaggtt cagggcttga ccctaatata agtccggact ctgcaaaaat
    23221 tcagatacct gctgtagcaa aagcgtcagg aatatcagaa agtaaattac aaaaaattgt
    23281 agatgataat acttccaaaa aagtttttgg agttttaggg gaagatagag ttaatgtact
    23341 aaaggttaat gtagaggtcg caagaatatt aggtcttata tagcattttg tagaatttta
    23401 gtaacaaaat atcatgcaag atttaattta aaggttagat tttaaagagt gaaaatcgat
    23461 aatgattttc acttttttat ttgaatatta ctaatatttg gaataaagcg attgtaagta
    23521 taaaatccaa aaaaaggttg cattatcaaa atgataatac tataatatat ttatcgttat
    23581 caatttgata atagattttg acatatagga ggaaatagta tgttatataa taatgcatta
    23641 gagttgatag gaaacacacc tgtagtaagg ctgaataatt taggttgtac taacgggtgt
    23701 tctaacatat atgtaaaatt agaaaaagta aatccagcag gaagtataaa agatagagcc
    23761 gtttatgaaa tgctagaagg tttagagaaa agaggagaat taaaaaaggg agatgtacta
    23821 gtagaagcaa ctagtggaaa tactggtatt gcattatcta tgataggaaa attaaaggga
    23881 tatgaagtcg taattgtaat gcctgaaaca atgagtattg agagaagaga tttaatgaag
    23941 gcttatggag caaatttggt acttacagat ggtaaagctg gaatggcagg ttccatagaa
    24001 aaagcaaatg aacttttaaa agaaaatcca aactataaaa gcttaaaaca atttgaaaat
    24061 aaagataatc caaatgcaca ttataaaaca acagcagttg aaattatgaa tgatgttaaa
    24121 gatttagata tatttgtatg tggagttgga acaggtggta ctttaatagg aactgcaaga
    24181 tatttaaaag aacaaaatcc aaacataaaa gtagttgcac ttgaaccaaa aaaatctcca
    24241 gctatatcag aaaacaagac tggacctcat aaaatacaag gtataggtgc taactttgtt
    24301 cctgaaaatt atgattctag tgtagttgat gaaataatat tagtagatga tgaagatgca
    24361 tttgatacag ttaaattact tgcatcaaaa gagggaattt tagtagggat atcttctgga
    24421 gcaaatatat ttggtgctat agagatggca aaaagatatc cagataaaaa gatagttaca
    24481 gtagctccag atggagttga taagtatatg tcgatgggaa tattttaata attttatttg
    24541 agggagtgaa tactttgttt aagaaaataa ataaagatat tgaatatata atgaaaaatg
    24601 atccagcagc taggtctaag atagaagttt ttttacttta tccatcagtt catgcaatga
    24661 taatgcatag gatggctcat gctctttata agaagaagaa gctttttaca gcaagattaa
    24721 tatcccagat atccagattt atgactggta tagaaataca tcctggtgct aaaatgggag
    24781 aaggtatatt gatagaccat ggaatgggtg ttgtaattgg agagacagct gaagtaggta
    24841 atagggtgac aatatatcaa ggagctactt taggagccac aggaaaagat actggaaaaa
    24901 gacatccaac tgttggtgat gatgtattaa ttggtgctgg aacaaaaata ctaggtcctt
    24961 taaatatagg ttcaaattca aaaattggtg caaattcggt tgtcgttaag gatgtaccta
    25021 atggtgcaac agttgttggt ataccagcaa aaatagtaaa aataagaaat ctagaacctg
    25081 taaaaaagaa taaaaaagaa gtagactatg agtatgatga attagataat gtatattata
    25141 tataggtttt gtataaccat aaaataaact ttataaaaat tatttttaaa aggtattttt
    25201 ttcaaatttg agggcataat aaaaaagaac tgaatgttac agttttggtt catcaatttt
    25261 tgataaacaa gattttaaat ttgtagcgtc taggaggttt ttattatgaa agcaaatgtt
    25321 aatcaagata cttgtatagg ttgtggatta tgtccatcaa tatgtccaga agtatttgat
    25381 atgaatgatg atgggaaatc acatgttata gttgatgaag taccaagtga tgctgaagaa
    25441 tcagcagcag aagctagaga aagctgtcca gttgatgcaa tagatgtgca ttaataaaat
    25501 aaatgcctat aaaaattgaa ttttcaattt ttataggcat ttgtctttta ttcagtcagt
    25561 atttcaacac ctgtttctgt aactaaaacc atacattccc attgagcaga taatttacca
    25621 tcttttgtat aaatagtcca attattttct tcatcaacga aaatttcgtg agttccttca
    25681 tttaccatag gttctattgt gaatatcatc ccaggaacta ataacatctc agtccctttt
    25741 ttagatacat aacttacaaa agggtcttcg tgaaagctta atccaactcc atgaccacca
    25801 atttctctaa cgacagagta tccatttttc tttgcataag agttgacagc atcacctata
    25861 tctcctaaga atccccatgg tttggcaacc tcaagacctt tttggacgca ttcctttgta
    25921 acttgaacta gtttttttgc attttcgtta acattaccta ccataaacat tcttgaagcg
    25981 tctgaatagt atccattaaa aatagtagaa acatctacat ttataatatc tccatctttt
    26041 aagataatgt ccttatttgg aataccatga caaacttcat tatttattga tgtacatacg
    26101 cttttaggaa atccattata gcctagtgga gcaggaatag ctccattttg tagtgtaaat
    26161 tcatgaacta acttatttat atcttctgta gatattccaa cttcgatttt atctgaaata
    26221 taatccaaaa tttttgtgtt tattacagca ctttttttta tttcctcaat ttgactttca
    26281 ttttttataa tgtcatgagt tggtacaata tgacctaatt tagcaaatga atctatttta
    26341 ttatccatat ccatatgaca ttttttatat tttttagtac ttccacacca acagctatca
    26401 tttctattta acttcataac ttttcatcct tcttttatta tttatttaaa ttatgggtta
    26461 cataaactat tttaaaacat aaccattata aatattataa cataaatact aaaaaatcct
    26521 ttatagatag tgatttattc aaaatataaa ttatcatgtg attattgttg atgaaaagag
    26581 tacagttaaa tgtattattg gatagtagta cacttaatag tatagttcaa gtttttcaag
    26641 aaaatcatat gtcagaggac aattttcctt taaagtattt tttgaatctt catcaagata
    26701 atagtgtaca aatgattctg caaaaaattc ttctataaac ttgcttatat atgcatgtgc
    26761 aatttgttta gggtcataaa gtttgtatct ttcctgagca aatactttca taaactcttc
    26821 agaatttgat tttttattta aaacgttttt atctatagca tgtgcagttt catgtaattc
    26881 taaattttta gatgaatgta catttgtata gctaggatta ctataaccta ttttagcaac
    26941 tatagaatta tttctatata taccaggtac atctttccaa gtcttgcctg atcttaccca
    27001 gcatggaggt aattgatatt ttaaatcact aaattctggt tcatcagtta gatttgaatt
    27061 tattaatttt atttttatat ccttttcttt aagtgcttgt aaatatttaa tatttatttt
    27121 tgcaagtctg cttttcatat tttcaacttc atctttatca taattcaagt catcaggaag
    27181 tataagcatt tgttcaatta tatctatgtt actgtctttt atatcttcag actcttcatc
    27241 aaatttatat tgaagattat cattttcata gatagttata tttgtattat tttccataga
    27301 ataagagtga atatcctcta agtttaaaat attcatttgt tgtaaaatat gttttgtttc
    27361 gccactccat actactaaag aaagtgaatt aaaattaatt agtggatttt cttttgcttt
    27421 tatatcattg cttatatcga catcaaatac atattcaatt gagtcctcta tgttaaggcc
    27481 atttgtattc tttttaatat acaaatacgc ttgttttaag tctatataaa tctcatctaa
    27541 agattcgtca taaaattctg ataaattatt agtaaagagt tcttcactta aaagttcatt
    27601 tttatcagtt atactttcga ttaaaatatt aatttctttt atcatatcgt aaatacttat
    27661 ttttctattt gcttcttcac tagatacatt gcatggcgca agagcaatgc aataaaaatc
    27721 tttttctttt ttataaaagg ctttaagtga ttttgataaa agtgtaaagt ctacacctat
    27781 ctgtaaattt accttaagtg aatcattttg tgataattca gtattatttc ttttagctgt
    27841 atttaaatta ttttccataa tcattgcccc ctttttatta gggtatcata atttttttat
    27901 atgtgtcaat ttattttttt gaaaattata atttttttga aaattttatt ttttataatt
    27961 tgttaatttt ttattataga aataaagatg ttattattat gtcaaaattt agcattagat
    28021 tcatgtagag tatattttat atacatatat tataattaac tttttgaaga ttgcatattc
    28081 aaaatacaca ccattttttt taattctata atataatatt tatatattta atgttaggat
    28141 gtgatttaag atgtatttta catatattat aagatgtaaa gatgattctc tatacactgg
    28201 atataccagt aatatagtta gaagaatgaa tgaacataag ttaggagtta attcaaaata
    28261 cacaagagca aaagggttta aaaaactaga agtttatttt gtgactaata caaaaagtaa
    28321 tgctatgaag ttagaatact atataaaaaa attaactaga aataaaaaat tgtctataat
    28381 aaaaaatcca aatatactta taaattcaat taataataaa actgattata ttattgggaa
    28441 agaaatagaa taattaacat aaacattcat agtaacatta taatgagtac atatagtgta
    28501 aaaacttgac aataaatact attgtaatat aatgaagtta tgaatatagt aaattaaaat
    28561 agctagggga gccaagagct gagaggtata ccgaccctta cacctgatct ggataatacc
    28621 agcgtaggaa agcttagtaa aaattcaagt atgtattatt tgtgatatat gctatttcta
    28681 agctatacct attgtaggta tagctttttt aattaagtta tttaaattaa actttaggag
    28741 gcaataatga gtaattataa aataccaaca cttacaatag ccggttctga ctcatctgga
    28801 ggagctggga ttcaggcaga tttgaaaacc tttagtgcaa ttggtactta tggcatgagt
    28861 gtaataacag ctataacagc acaaaatact caaggagttt ttgctgtaga ggacttaaat
    28921 aagaatataa taaaaaaaca aatagaggca gtctttgaag atatacctcc aagagctgta
    28981 aaaataggaa tggtttcaag tcctgagatt atacttgaaa tagttaagaa tctaaagaaa
    29041 tacaatccaa aatatttggt ggtagaccca gtaatgatat ctaaaagtgg atattatcta
    29101 ttaaagccag aggcaaaaga aaacttaatt aagtatttga taccacttgc atacataatt
    29161 acaccaaata taccagaagc agaagaaatc acaggaataa aaatacataa tgtagatgat
    29221 atgaagagag taggaaaaga aatactgcaa cttgggccta aatttgtact tatgaaagga
    29281 ggtcatttag atggagaagc ggtagatatt ttaattggta aaaatatatt taaagtttat
    29341 aaaagtgaaa gaattgataa aaaaaataca catggaacag gatgcacatt atcttctgca
    29401 ataacatctt atctagcatt aggatatgaa ataacagaag cagtaaattt tagcaaaatc
    29461 tatataacag aagcaataaa aagaagcttt gatataggtc atggagtagg accagtacat
    29521 catttttata aatttgaata ataaaaaaat attggaggta gaatatgtat aatttaatta
    29581 aagacgtaaa aaaattaaat ccattggtaa ttcattatac taataatgta actataaatg
    29641 attgtgctaa tgcaacttta gctgtaggag caagtcctct tatgagtttt tcatatgaag
    29701 aagtagaaga aatggtaagt gtagcaaact ctgtagtaat aaatatagga actatgaact
    29761 caaatatgtt ggatttgttc ctcttagctg gaaaagcagc aaataagtac aataaacccg
    29821 ttgttttgga cccagttgga gtatttgcaa gcaaagcgag agcagaactt acaagtagac
    29881 ttttaaatga agtcaaattt agtgttgtta aagggaatgt gtcagaaata aagtttatag
    29941 gtggttttaa tgtaaggggt aaaggcgtag attcatttga tgaagaagat tctactgata
    30001 taataagaaa agttgctaaa aagcttgaat gtatagttgt agcaactggg aaaatagata
    30061 taataactaa tggtaaaagt acatacaaaa taaacaatgg aactgataaa ctgaaaggaa
    30121 ttacaggcac tggatgtatg actgctagct taattgcaag ttttatggct gttactgaga
    30181 atatattaga agcagcaaca atgggtgttc ttacaatgtc tttaagtggc gaattggcta
    30241 atttaaataa tccgccaata ggtacattta aagaaaatct tatgaatgct atttatcaaa
    30301 tggacataga tactttaagt aaaaattcta atattgaatt tttaaattaa taaagagtaa
    30361 gggagactta aaatgataga taaagaatct ttaaaaaaat gcttaagatt gtatttaata
    30421 actgactctg aaatgcttga aggtagagac ttttataaat gtattgaaga tgcaatatct
    30481 tctggaataa caactgtaca gcttagagaa aaaaatactt gtggaagaga atttttaaga
    30541 aaagctatga aacttagaga aataactaaa agatatggag ttaagtttat aataaatgat
    30601 agagtggata tagcacttat ttgtgatgca gatggggtac atgtaggaca gagtgatatt
    30661 gatgtgagag aggttagaaa acttatagga aacgataaaa ttctaggagt atcagcaaga
    30721 actttagaag aagctatttg tgcaaaaaat gatggtgcag actatttagg catagggtct
    30781 atattctcaa catctactaa attagatgca aaatcagcct catttgaaac tgttaaagaa
    30841 attaaagaaa aagtagacat gccatttgta ctaattggag gtataaattt agacaatata
    30901 gataaactta aatgtttaga tagtgacggg tatgctataa tatcggctat actaaaagct
    30961 gaagatatat ctaaagaagt agaaaagtgg acattaaaaa tataaaattg gctctagtag
    31021 tgaaaaaaat ggaaaaattt gatataatct aagagtaaaa tttaagaaat tataaatgat
    31081 aaacttttct acatatactt tttaatcaag atatatgtag atttggttaa aaaggagtta
    31141 taaatgatta ggatattgtt agtatgtgtt ggaggcatgt cttccactct attggtaaat
    31201 aaaatggaga aggacgcaaa aaagagaaat atagattgta aaatatgggc agttggagaa
    31261 ggagatataa aatcagagct tgataacttc gatattttac ttcttggacc acaacttaga
    31321 tttatgtttg atgatgtaaa gtctatagtt ggagatagag ctccagtgtc tataatagat
    31381 atggtaaact atggtacttg taatggtcat gctgtgttaa attcggtttt agaaatatta
    31441 aaataaataa taaaagtgga ttctatataa tagagtccac ttttattatt tgttattaat
    31501 ggatttaaaa cttagcttac catttctttt tttaatctcc acatagcaag tgaaaaactt
    31561 gcacagcaca atattaaaaa tagtaggata acaggtagta tatcttcaat aagaacagtc
    31621 tcaccaaata ttaagctacg taaagcgtta ataacatggg taaatggatt gagcatcact
    31681 accactttta atcctccaga taaattttct atagggaaaa gagctgaact taaaaagaaa
    31741 ataggaagta caattgcagt cataattgtt tcataaacta tctcatttgg caacaataaa
    31801 cttatagaat aagctagact tgataaaaag aaggcggtca taaatacaag cactgtcata
    31861 agtaggattc caccaatgcc agattctatc gttactgaaa agaatatact tactatacac
    31921 aaaatagcta cttctatgaa ggaaactaag atagcttcta ataattgacc aaggacgatt
    31981 gaatacctac tgataggtgc aattaagact ctatagaaac ttccactatt cttcattata
    32041 aagttgatga taccaccact actacaagaa gaaaacacaa ccagtataat tatacctggt
    32101 agtataaaag cagtataatt attgatattt atattattca tagtttggtt tgcaatagaa
    32161 ctataaagca caagccaaag aaaaggttgt aatatagtaa ctataaatga gattggattt
    32221 ttaaaacgcc acttcatact acgccataag atatttaaca ttcccatccc tcctttaggc
    32281 tttttttaga acttgtaagt gctaaaaata catcttcgag acttggttcc acaatttcta
    32341 ttgcatcaaa ttctatatca tgttctaaaa gccatttatt tattaaagta aaagcagttc
    32401 tactatcgtt tacacttata aaaattgaat tttctcgtac attcataaac tttactaaac
    32461 cagtaccctt aattgcatca ttatattttt ttatatcttc agtattatgg aaagttatac
    32521 gtattatatt ttgtctaatg taactacgta aactggatgg tgttccttgt gctaaatctt
    32581 ttccattctt cataatacaa atgttatcac ttaattgttc agcttcttca agataatgag
    32641 tagttagaaa tatagttgtg ccatactcat atctaatttt taataacata tcccacatag
    32701 actttcttga atctacatcc ataccgacag ttggttcatc tagaaataga attttaggag
    32761 atgataccat attcatagct atgtccaatc tacgttttac accacctgaa tatgatgaag
    32821 taggatattt taagtaacta gataagtcaa acttatcaat taaagagtct attctttgtt
    32881 ttgcaatctg tggttttact ttatacatct tgctttgaaa tatcatattt tccataagag
    32941 ataagtgttc atcaatagag atttgttgtg ctacacaagc aatttgagta cgtatccaag
    33001 aaggattatc tactaaatct tttccaaaca ttgttacatt tccagatgta ggcttgtaaa
    33061 aagtagtcaa aatattgata agagaagatt taccagcacc attagggccg agcaaagaaa
    33121 aaatttctcc agaatttaca ttaaagctta gaccatttaa agctttcaca ccatttttat
    33181 attcttttac taaattgtct atttcaactg ctaacatata ttattcctcc tctttaagtg
    33241 gaaatattat ctctgtaata tagttatctg gttttccttt taccaacata cctggtcctt
    33301 taataaatac ttctctccaa ggagtttgta tttttatatt attttcatga atatatttaa
    33361 atatcatttc atacgttttt ggcaaattac tataagaacc tatatgagta aaaaacaaag
    33421 cttttgtttt aggaaattct tttgtagtta tacccatgcg atttggagtc tcagcagttg
    33481 gaacacataa ttccatttct gcaacaccag ttttttggtc aacatcatag tagcaaaaga
    33541 atggtgcacc gttagacttt ccttttatag ctttaaatac atttggaaaa tattttgttg
    33601 cctcagtcat aggtccatta taacgcatgg tagctactgt gactgattca atatttttga
    33661 ttttataact catttgttta cctcctaatg tgtattcata tttttattag atttttaagc
    33721 atcaatacat ataagatttt gattagtaga aagcatataa tcttatctcg tttgcttgtg
    33781 ttcaagtcta acataacata aaatatatat cctctcattt gatgctccat tttgtaaagt
    33841 tattatttaa gctttatttt agttttttag taaatttaaa ttaaaataaa ataatgtata
    33901 aaaaaagtgt ttacaaacta agtgtattaa tcgtataata cacttaatag gatactagat
    33961 aaggtctgaa ataaagacat atttttttaa agtaagtgta ctatcgtatt aatacactag
    34021 aataggagga accatgaact ttgaattaga taatacaact cccatttatt tgcaaatagt
    34081 aaagtatata aagagacaaa tagtaatagg agagttgaaa ccaggggata caataccatc
    34141 aagaagagaa atggcactta atctaaaagt aaatttaaat acggttcaaa gagcatataa
    34201 ggagatgggg gatatgaata taataaatac ttttaaaaat catcaaagca gtgtaacaat
    34261 tgatgaaaat atattaaaaa atttaaaatt agagcttata aatgaatcat tatctgtttt
    34321 tttaaaagat atgaaagcaa taaatgttac caaagaagaa gttttaaaga taatagaaga
    34381 taagtattag ttttttaaca tatagaaaac ttagtttaga aagtttattt ataagcatat
    34441 tggatgtgga ggatagtaaa tatgatagaa ataaaaaatg tcagcaaaac atataaaagg
    34501 atgcaagggc ttaaaataag aaagatagag gctttaaaaa atgtaagttt taatatagaa
    34561 aagggaaaaa taactgcatt acttggtata aatggcgttg gtaaatcaac tatgctaaaa
    34621 gcaatagcag ggcttataaa cactgatagt ggagagattc gtatagatgg agaaaaaata
    34681 aatgaaaaga tatacaataa attggctttt gttccagatg tacaatctca cttcagtaat
    34741 acaacaataa aagaaacatt tgaatttatg gaaatttttt attcaaagtg gaataaaaaa
    34801 aaatcaaaag aaatgatgaa catatttaaa ttggatgaag atgaaataat tgataacttg
    34861 tcaaaaggaa acattgcaag agtaaaatta atacttggat tttgccaaga cccagagtac
    34921 atacttcttg acgaaccatt tacaggaatc gatttgttta agagggaaga atttatagga
    34981 gtaatagcgc aatatatgga ggaaaatcaa gctattatca taactactca tgagatagta
    35041 gaaatagaaa gtttagttga tgaggttata attcttgatg aagggcagat tatagcttca
    35101 tttaatgcag aagaattaag agaaagagaa ggtaaatcta tattagataa gatgagggag
    35161 gtatataaga atgaataaac ttctatatct aataaatgta gatttgagaa gaagcaataa
    35221 gttttatata gcttatatat catttttttc attaattaca cttggtttaa atttattcga
    35281 aattaataaa tttaaaaatt ctaaatttat tataaactta gcaataggag attttggagg
    35341 tatattttat ggaataggta tacttagtaa tcttggtttt atccaaagta tattgttctt
    35401 tgggatgttg ggacttttta tatactatat ttttatgtgg aaaagagagt ttttttcgaa
    35461 taatcaaagt atttatacac taatgatgtt acctcaaaat aagtttaaga tttgtatatc
    35521 taaatcaata gctttgttaa caatgatata tggttttttg ataagtcaga tagcaacatt
    35581 atttatatgt aaatatatat ttaattttat ttttagaaat gtgccaataa tcaatatgaa
    35641 ctttgccaaa gatttatatt atttaaattt gaagggtata ccaattgatt ttatctcttt
    35701 tatggctatt tatgtatttt tactacttat agctatttct attgtaaatt gttgtatatt
    35761 atttatcttt tcctatataa ataaatttta tatactttta atcactttgt tgattatagt
    35821 aggcttatat ttttcaacaa tatatataag tataatcact ttatttagaa aatattatat
    35881 ggctatagga tttcaattta ataatttagt agcaggatta ttaagttttt taattataat
    35941 gtttattcta aatggaatat cttatttgtt aattaaaaag aaaatatctc tttaggaggg
    36001 gtggtatgaa attaaaatct aaaatatcta tacttattat atttttgact ttagcaatat
    36061 attttagtat aggtttatta aataatgaag ataacttaaa gataaaaact ataaaaggag
    36121 atcctaatga attagactat ataaacataa attttggata tgcttttaat ggatatgtaa
    36181 attcatatta tacaataaat ggaagtaaca aaaccaaaaa gactgaatta ataaaactac
    36241 aaaaagatgc taagaacaca aataatttaa ttgatgtatc tagtggttca gatttaattg
    36301 ctcatgttgg atttgaaatg aatgatgact caaaagatat aaactttgta atagatgaaa
    36361 aaaaagaaga tttagaaaaa ggtgtatttc catcagaagg agatgataaa gcagttgaat
    36421 atgaaaaact agatatgaat gattttacaa ggacaagata taaagtagat aaaagttctg
    36481 ataattacta tgcaaatata ctatcatcaa aaagatataa aaaatactta tatgtatctg
    36541 tactttatgc tacaagtgat tcatcaaaaa acaacaaaga atattcaagt actatagata
    36601 taataaaaat aaatccagaa aataaaaaaa tccagactat aaaaagtata aatttaagta
    36661 attatttttc taaaaaatac caaaatatag ataatataag tgtaagttat gctagcaaat
    36721 atgaggataa gatgtatatt ttagtaaatg tattaaatgc aaatacaggt gataaaagta
    36781 attctaaatt tcacttactt gagtataatc ttgaagaaaa taaggaaagc ataatggaat
    36841 taaaaactga tagcaaaatg gctttagcaa aagtaaagtt agaagataat aaattatata
    36901 tggtaatgtc aaatgactat gataatagtt caattacaga gttaaattta cttacctata
    36961 atatattaga taaaagctta gatgaagata agtatatttt agataataaa gaaaaaagag
    37021 gaattagaag tattgaaatt gattcaaata aaatcattgt atatacatca aggttaaatt
    37081 ctacattatc ttgggataat aaatttatgt tatatataat aaataaaaat tctaaggaaa
    37141 ttgtatatga aggagaatta caatttaaca gttcaaatag tatgttagaa tttgaaataa
    37201 agtaggtgag ttgatgaaag atttaataag attattcgaa tttgaattaa aaagaaatat
    37261 aaaaaattat atatttataa taatctgttg ttgttccttt gtaattttaa acatagtaaa
    37321 aaatttaaat gactataatt acataataga aaatgcagtt aaaagtgaac agttaacaaa
    37381 aataggaaat actatagaaa cagtaaatgc tataggtttc tcaagtttta gaaatataat
    37441 gggttataca gaatcatggt ttatgtttgg tataattgta tgtatatgct atgctttttt
    37501 tatttggtat agagacttta atgggagaag taaatctata tatacactta taatgatacc
    37561 taaaaataga attaatattt atatatctaa attattaaat atattatttc tagtgtatag
    37621 ctatacagta gtacttacaa tatctttatt tattacaagt aagttgttgc ctagacatat
    37681 gcttgggaat gttacaagct atggttttgt acaagaaaca atatataatc taaaaatgtt
    37741 acttccatat agctttgaaa tactatttgt acagtatata tttttattga taggatttgt
    37801 atctgtagta tttacatcaa ttcttataaa taaatctatt tatagagtaa gcgctttgat
    37861 aagttttcta tttttagttt tggaaatttt agtgtttata atttctatag aatttattat
    37921 accttacgaa tacagtaatg tatttactgt tctatattca agtataaaca tatttgtatg
    37981 tagtcttata tctaataaac ttttgaagca aaagattgac ttttaggagg gatattatga
    38041 aagcaaaaaa tataggaaaa tatacaatat gttttataat agtgtgtttt ttaatgatta
    38101 ctatgacctt aatattgagt tattttaata aggataaatt atctgtaaaa actttaaaag
    38161 gcaatgtaaa agatataggt agagtgagtg tagtatatac acctaatata agtaaatttt
    38221 cttatgatga ggtaattata agtaaaaatg gagtaagaaa taatacaaat cccacatcaa
    38281 taattagaaa tgattattta aatattgaca aaaaatacag tgattttgtt aatgataaag
    38341 gaaaagatct tatatataaa gatgatttga atataggaga agcatatact tctgttaagt
    38401 acgatttagt acaaggaatg aatgctttaa atgattgtat aaaggtttca aataaaaatt
    38461 taaaaagtgg ggcagaagaa aattttgata ttaatttaaa caagtctgat tttaaagaaa
    38521 acagttggaa aactttgttt aataaaatat ataaaggcaa tttatatatg gtgattagtg
    38581 aaactaatat ttcaagttct aaagtcaata atatttgtat attaaagata gatataaaaa
    38641 ataagtctta taaattatta aatagattta atttagtttt acagaatgga tatcaacaaa
    38701 atatcaatga aattaaattt tctattggaa gtaaattata tttagaaata gtaaataatc
    38761 aaagtacaaa tgaagatatt gaagaacatg ataattactc taactttatt atatatgata
    38821 tagaagaaaa cacttttaat ataagtgata aatttatgga taatctaaat aaagaaaaga
    38881 atgcaaatcc aaaagagatt ggtttattag gtaaaactaa gctagattat atggtaaaaa
    38941 ataataaatt aaatcttata gttacagata tgagtaattc tataacaaat cttgtttatg
    39001 atattaattc taataagatt aaattagaag attatgagat acttgattta aaagtggatt
    39061 ataatgaagc atcatctgga attaggaaag ttaagttact ggatgataag atatattcta
    39121 tttcaggtat aaagaataat ctatcaggag aattaaaagg gtttaaaggg gttgttgata
    39181 tagttggaac taatccggta aaatttaaag tatttgatat gaaacttaaa aaaaccgttt
    39241 atgaagctga gctaataaat ggagatgtaa gtttacaaga aaagttattt tttgttgcaa
    39301 attaagtgat ggaattaatt ttataacttt aaacttttat atgtattgta ggtgaatata
    39361 agtaaaggag tgtcttaaaa tgaatttttt agctcatgag acactctttt ttatatgaaa
    39421 tcaaatatat ttttatcatt tagacaatga aaaataagat tatctctatt ttaagacaga
    39481 catttgttta taattatata caaaaacatt ttttaatatt tttgtatagt atataataat
    39541 ttaatttata ttaatacact taaatttgaa atagaatgag tataatggta aaattaatta
    39601 ttagaatatt agaaataata aataaataat acattgtact taaaaggggg agaaatttaa
    39661 gatgaacaaa aaatatatta aagcaggaaa tttaattgat ggaacaggaa atagtaccat
    39721 gcaaaataag ggtataatta ttgatggaga tactatagtt gaaattgaag atataagaga
    39781 agatttaaat ggctatgatg tgtatgatta cttagataaa actgttatgc caggtattat
    39841 gaattgtcat gttcacttga caatggagcc agttggaaat ccaaaagtat attatgataa
    39901 tgtatcagat gtagagcttg tagtaaatac gataaaacaa cttgatgctt atttggattc
    39961 aggagtaaca tatattagaa gtctaggttg cccaaaatat gtggatgtac aacttaaaaa
    40021 tcttatagac aaagggtcta tagatggtcc tggtatagtt acttcaggtc cagttatatg
    40081 catgacagga gggcatggat actattttgg tattgaaagt gatggagtgg acgaatgtag
    40141 aaaatcagcc agaacagttt taaaaaatgg agtagattgt gtaaagataa tggcaactgg
    40201 aggtgtaaca actgatgggg ttgaaccagg gtcaccacaa ttaactttgg aggaaatgaa
    40261 ggctgctgta gatgaagcta taaaggcagg caaaataact gccacacatg cacaaggaag
    40321 aactggtata aaaaatgcag tgcttgcagg aattacttct atagaacatg gtgtttattt
    40381 agatgatgaa ataattgatt taatgcttga aagaggaact tacttagttc caactgttgc
    40441 tgcaccatat tttattctaa atgcaggaaa agaaagtgga ataactgaag ctactcttag
    40501 aaagtgtgag attgttgcta ttccacacaa agagtcattt ctaaaagcat ataaaaaagg
    40561 aattaaaatt gcagttggtt ctgatgcagg aacttcttat aatgaacatg gaaaaacata
    40621 ttatgaaatg aaactaatgt cagattatgg catggataat atggatataa tagttgctgc
    40681 tacaaaaaca gcatctgaac ttttaagaat tgataaaaat tatggaactt tagaaaaagg
    40741 aaagaaagca gatgttatag ttgtagatgg aaatccaata gagaatatag atgtacttgc
    40801 agatgtgtta gcagtattta aacttggtaa aaaagttaga taagtaatat aaaaaataaa
    40861 aaagagtgtc taaagggatt tttaaataat tatagacact cttttttatt agtaacaatt
    40921 aagtctttta tactttaggg actagattct attttatatt tagatataac tctttaaaat
    40981 cattctatgc aatataatct atagaatcta cacatacaaa gtatattctt gaatcattag
    41041 aatttccaag tactagaaca tcatttttct tacctagaac ttcaacacca gttagaacca
    41101 aactaccagc tactacagta acttgattat ttatattaga catataaaga ttatctagga
    41161 tacctttatt acaacagcag tcgtcacaat cacagttaca attacattct ttataatgct
    41221 ttttgtcaag atagtaagct aaagatgata tgaaatcttc ataatctgca ggtgtaacat
    41281 taaaggcaac agctttaaga ttacataatg atgctaaatc tacatttgtt aatgggttaa
    41341 ctgtagaaat tatataatca attatataat caagtattga atttagtata gaaccaaggt
    41401 ctatagtagc aggaactgct gcttctataa gagcgactaa ttcggatact cctgggatag
    41461 taccaattga agtaactagt cctccaagtg ttaaaggaac aggtttagga taatacaatt
    41521 gaccagatat atcaattaaa tcacagttac aagctgaaaa tctttcaaaa gtgccattaa
    41581 gtccagataa attatctttt ggaggtattg aataatctat acctactaaa tatgcaccaa
    41641 caataaagaa atctgaaata aaagcaaatt gattaaaatt tacaaaaggt cttagagaat
    41701 catatcttaa aagttctaat gcctctctca tgctcttttt acaacaacat tttgtcattt
    41761 taggttcttt atatttattt gggtaattat agtatctatc agctacttga taattttcat
    41821 agtatctatc atttgcattc atataatctt cttcgtattc ttgagtaaat ctaaagtcct
    41881 ctctacattt attattttcc attaaataca ctccttttat attttgattt aaatgtatag
    41941 ataattaagt ttatctatat agtaatatta tatttattgt gtaaaaaaat gttacaaaag
    42001 aaattataaa tgaataaaaa ataataattt gtcaaataaa ctcataaatt attatgaata
    42061 atctattcta aagtaaaaaa ctatgtataa aaaaggttta tatgttatat ttatataaat
    42121 ataacatatg aatgagaaag gagtagtttg ataaatgatt gaggtagata aattatgcaa
    42181 gtcttttaca agggttgtaa aagatgataa gaataaaagt tcaataagaa agttaaagaa
    42241 aataaaaact aaaaaagaag aattttttgc tgtaaataat gtttcattta aagttataga
    42301 aggtgaaatt gttggaatat tagggccaaa tggtgcagga aaaaccacat tacttagaat
    42361 gttaggtggc atattaacac caacatcagg aagtataaat gtttctggat atgattattc
    42421 aatagataga aattcagcca aaaaagaaat aggctatctg tctggaaata caaaactata
    42481 tggaaggctt tctcctagag aacttctaac aacttttgca agtctatatg agatgtcaaa
    42541 agaagagata gaagaatcga ttgaaaatgt tgtaaaaata atggatatga gtgaatttat
    42601 agataataga attgaaaatc tatcaactgg tcagacccaa agaacatcta tagctcgttg
    42661 tttaatacat tctccaaaag tatacatttt tgatgagcca acactaggtc tggatgtttt
    42721 aagtagtgca tccattatag attttatgaa gaatgaaaaa ctaaggggaa aaactgttct
    42781 ttactcaact cattatatgg aagaagcaga aactttatgt gacaagattt ttatgattca
    42841 caatggggaa ataattgcat caggaactcc acagagttta aaagaggaat ctggagtaaa
    42901 taatttgaga gatgtattta taaaacttgc cagaagggag gatatttaaa tgagaagtaa
    42961 gattgtaaaa tacatattta aaaaagaaat gttagacata ttgagagata aaaagacttt
    43021 atttatgatg attgttgtgc cacttctttt atatccttta cttatgttgt tgatgattca
    43081 agtaatgaat atgtctgcaa gtagtatgaa tagcaaggac attaatatag ctttcaataa
    43141 taaaccaaat aaagtgttag tttccatgat tgaagatgat aatttagaaa aaaatattaa
    43201 aaatacttca agtgataaag gaaaaataag agtgttagat gtagataact ataaaaagtc
    43261 attagaagaa aataaaattg atgcttatat aaagatagaa gaaaaaaaat catctacaag
    43321 ttatcgaata tatataaatt cttctcaaga aaattcttct aatgcagtaa aaagaattga
    43381 aactgttttg gataaatata aaagatctac tatagaaaag actttatctg aaaaaggatt
    43441 agatgtacaa gctactttag aaccaataac atatagcact gtagatgttg caaagacaga
    43501 agaagtggca ggatactttt taggtcagat actaccattt atattaataa taggagtttt
    43561 actaggttca atatatccag caatagatgt tatggctgga gaaaaggaaa gaggtacgtt
    43621 agaaacatta tttacacttc caatatcaaa cttagaacta gttatgggaa aatatatggc
    43681 agtttctctt agtgcaatag taacagcaat tttaaacatt ttatctatgg gactgactat
    43741 gacatttatt ttagttagtg gaggtattag taaccaattt ggctttggaa actttaatta
    43801 tggagattta gtcttgccaa ttataactac cttaatttgc atatgtcttt tttcaatggt
    43861 agtttcagca ataagtatgt gtgtatgttc attagcaaaa agttttaaag atgcccaaaa
    43921 ctacataaca cctcttatgt taattattat gataccatca tatgtttcta tgatacccaa
    43981 tatagtattg gatagagtaa cagctgtaat acctgtagta aatatatctt tacttataaa
    44041 aagtgtatta tcctttaaaa gcgatttaaa tttaatagct ttagttttag catcaaatgt
    44101 agcctttgtt atattggcaa taatactact gtctaagatg ttcaattctg aggaaatact
    44161 ttttggtaat agtaagagtt tctctttctt agagaaaaga agtaatataa aaaaagggtc
    44221 tataccaact gtaagtgatg gtgttatttt atatgcagta ggattagttt tattgattta
    44281 tgttggttct ttagttcaaa ttaaatttgg tatagtaggt attataatga cacaattcat
    44341 tataatttct ttgccattat tatttgcata ctatattaaa gctgatttta aagaggtatt
    44401 tagcttgaaa attcctaaat taaagcacgt gtttgggagc attgttcttt ggattggtgg
    44461 ttatatactt attatgatta taacacagct aattttattc ttattccctc aaagtatgga
    44521 agttgctgaa aatttaaata aggctctctt tatgaaagat agtgttttat tgaatttact
    44581 agtaatagca ttattaccag ctatatgtga agaaatattt tttaggggat ttatattttc
    44641 ttcatttagt aaatcaaaag ataaaaataa gtctatcaag cttactataa tatgtagtag
    44701 tgtactgttt ggtattatgc atatggattt tattagaata attccaacat caatattggg
    44761 tattatattt gcatacagtg tgtataaatc tggttcaata tttgtatcaa tgttattgca
    44821 ttttttaaat aatggtgtag cagttatgtt aaatcattat acaactggaa atataatcaa
    44881 cttatataaa tttgttgaag ttgatttttc gaatttaaat gtacttgaat ttgcgttaat
    44941 tcttctaata agtcttatat tagttatgtt aggagcaaga gctttaggta gaaagtcttt
    45001 aagaaattaa gtataaattt aatatacatt aaaatattaa taagcactaa agtatatgga
    45061 tgtatcctgt atataaaaat actttagtgc tattttaatt atatgaatta tttattttag
    45121 aaatttatat ttaaataatc aagtataaag tgagatatta aaaaatcaac ttagtaatta
    45181 tttgatttat tcacttaaaa aaattaatta ttgatttgtc gaaactcttg caaaaataaa
    45241 aagataaagt atgaatatgt tgcaaacact gtgttttaat gaaaagtag
//
LOCUS       DAMKOJ010000027        43969 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000027 DAMKOJ010000000
VERSION     DAMKOJ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43969
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.029"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            93..1274
                     /locus_tag="PC592_001594"
                     /pseudo
     CDS             93..1274
                     /locus_tag="PC592_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
     gene            1390..3327
                     /gene="htpG"
                     /locus_tag="PC592_001595"
     CDS             1390..3327
                     /gene="htpG"
                     /locus_tag="PC592_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDF4055572.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKIIVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDTRNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEVVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFHVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKETVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKVTLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            3706..4836
                     /locus_tag="PC592_001596"
     CDS             3706..4836
                     /locus_tag="PC592_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF4055573.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKATGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKSSIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPIADVQAIYG
                     IELISENLVKVYNNVNDLEAWEKITLASTIGGMTIGTAGTALSHGMEHPVSGLRDVMH
                     GKGLAALTPVIIESSWDSDTERFGNISKILGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEEIKEMYRKSL"
     gene            5064..6086
                     /gene="splB"
                     /locus_tag="PC592_001597"
     CDS             5064..6086
                     /gene="splB"
                     /locus_tag="PC592_001597"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HDF4055574.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKNIYNKFKDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GKEEKGRFRFVTKYSDVDSLLDAKHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIRSIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFHKEINGVFKNS
                     LIKYII"
     gene            6253..7164
                     /locus_tag="PC592_001598"
     CDS             6253..7164
                     /locus_tag="PC592_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4055575.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLAKASEYLAEHKNRILDVALKFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVTRKTLSNPRTFVGIEMEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VELGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTAD
                     FAIEMYYPTTPEVAYLEHWIVPIPIEQ"
     gene            7179..7595
                     /locus_tag="PC592_001599"
     CDS             7179..7595
                     /locus_tag="PC592_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF4055576.1"
                     /translation="MNWQDTFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVNESNRVEVDLFINTCCDYIK
                     QIYNEVKFFNGGKWLMIQVDSLLVLNDMLELIKFRI"
     gene            complement(7695..8087)
                     /locus_tag="PC592_001600"
     CDS             complement(7695..8087)
                     /locus_tag="PC592_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055577.1"
                     /translation="MGINSEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESDGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNKCGLNCKECRKTK"
     gene            8228..8623
                     /locus_tag="PC592_001601"
     CDS             8228..8623
                     /locus_tag="PC592_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF4055578.1"
                     /translation="MKALEFLNKAGVYYLATADENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            9024..9230
                     /locus_tag="PC592_001602"
     CDS             9024..9230
                     /locus_tag="PC592_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055579.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGVEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(9536..10279)
                     /locus_tag="PC592_001603"
     CDS             complement(9536..10279)
                     /locus_tag="PC592_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF4055580.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIKNIPRIINNIIILRGCEANILDTKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNHPKKLINHFHQKGKLLDVDYRNI"
     gene            10445..13012
                     /locus_tag="PC592_001604"
     CDS             10445..13012
                     /locus_tag="PC592_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4055581.1"
                     /translation="MTQRKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFSNINSINEYS
                     EDDSIKDEYILEGIKKENNIFNLVGCDGSLKSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLNIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGILFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESIRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKSFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDEDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYVLQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANEIDKGKGILILTDMGSILTFAKVIHDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEITYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRSKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            13242..13646
                     /locus_tag="PC592_001605"
     CDS             13242..13646
                     /locus_tag="PC592_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055582.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            13670..14167
                     /locus_tag="PC592_001606"
     CDS             13670..14167
                     /locus_tag="PC592_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4055583.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEIELNHNINRY
                     KGEFI"
     gene            14170..14571
                     /locus_tag="PC592_001607"
     CDS             14170..14571
                     /locus_tag="PC592_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF4055584.1"
                     /translation="MNKYKVIILCHGTWGKLLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKGVEEAVDKEDVKIIISDLYGGSTSSVAISVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            14589..15077
                     /locus_tag="PC592_001608"
     CDS             14589..15077
                     /locus_tag="PC592_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4055585.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGSEDIKQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            15104..15859
                     /locus_tag="PC592_001609"
     CDS             15104..15859
                     /locus_tag="PC592_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4055586.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLNVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            15859..16722
                     /locus_tag="PC592_001610"
     CDS             15859..16722
                     /locus_tag="PC592_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF4055587.1"
                     /translation="MQEIKNKDVKNGQGTTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKKKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIIFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLSVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            16769..17248
                     /locus_tag="PC592_001611"
     CDS             16769..17248
                     /locus_tag="PC592_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HDF4055588.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGVNPDDIC
                     KEAIYGFGKMRGQKYSVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQSVRLEFAQKRAHDDEVCELVFTRK"
     gene            17313..18620
                     /locus_tag="PC592_001612"
     CDS             17313..18620
                     /locus_tag="PC592_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF4055589.1"
                     /translation="MDISRRVDNSLNRTIEFLKELIKIDSQQGEPILQCPFGIGPKKS
                     LEKTLDYCASLGFSVKNIDNYIGYAEIGEGKELIGIPMHLDVVPPGDGWSVDPFSGVV
                     IDNIIYGRGAVDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMECIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIILRGGTKENVVPSHC
                     TAKIVNGIILELTTKGVAVHASNPEKGENAISKMVIKILKDNMNFQHREDIELVSKYL
                     CSDYYGNALGINRYDGVFKNTTLNLGILKVNEEKIVCELDIRYGKNIILNNIIDRFKK
                     FFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            18937..19059
                     /locus_tag="PC592_001613"
     CDS             18937..19059
                     /locus_tag="PC592_001613"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HDF4055590.1"
                     /translation="MLSNKIIKKCCKIGYMIREKSIDIYSDSGWEFMVWDENGE"
     gene            19563..20657
                     /locus_tag="PC592_001614"
     CDS             19563..20657
                     /locus_tag="PC592_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055591.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     LDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTAKPFDEVMIEIREI
                     IKRYYSCFPLIFRMGLLIVNHYDIVDEKKRELLIDEALEIFIRIQETCNDIDICRQAK
                     NMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQIDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISNIFELDTLSPATMLSAYLTQTQINLIH
                     EDNEGAIKSLRKYVDLATSDIYPITIHGDDFFDKLDRWISEIGIGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            20662..20862
                     /locus_tag="PC592_001615"
     CDS             20662..20862
                     /locus_tag="PC592_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HDF4055592.1"
                     /translation="MENLMEYLPLLIPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISIIGPILYFTIGRGEE"
     gene            20862..21779
                     /locus_tag="PC592_001616"
     CDS             20862..21779
                     /locus_tag="PC592_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055593.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLEPDSGTIDVCGEKVTYGGTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKQEIKIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSGDIKSLLKYSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            21776..22534
                     /locus_tag="PC592_001617"
     CDS             21776..22534
                     /locus_tag="PC592_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055594.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLVFGIMSPLSAKFMPD
                     LIAHFAPTLKVTTAPTALDSWTQFSGNISGLGASLTLIVFCNILSNEYSKGTLVIMLT
                     KGLSRSSVILSKFSIAVIIMTIGFWLSFLCTYGYTMYFWPTENLNHIIFSAFNLWLIN
                     IMYITILILGCVLFRPAFASVLLVLVATLILSLISIPKQIAPYTPNFILSKNIDLVSG
                     KVAAPEFIIPMIVTIVISIICLLLAVILFKKKAV"
     gene            23010..24083
                     /locus_tag="PC592_001618"
     CDS             23010..24083
                     /locus_tag="PC592_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF4055595.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDKAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKECEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCIGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKIGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            24153..24416
                     /locus_tag="PC592_001619"
     CDS             24153..24416
                     /locus_tag="PC592_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055596.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            24622..25599
                     /gene="bioB"
                     /locus_tag="PC592_001620"
     CDS             24622..25599
                     /gene="bioB"
                     /locus_tag="PC592_001620"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDF4055597.1"
                     /translation="MEKYIIKLKNKVLGGKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREFFMGRKADLCTIINAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNDILKIYERLRENTNLKLCASLGIIDYEQAKMLK
                     SVGVTTYHHNVETARDNFHNICTTHTYKDRIKTIKEAKEAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMEDYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDEVGFNGGVNSAIVGDYLTTVGNGIENDKKMIIEQGFEI"
     gene            25827..26840
                     /locus_tag="PC592_001621"
     CDS             25827..26840
                     /locus_tag="PC592_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF4055598.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANKEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKYLLDTGNKKIIYLSGPLQNEIAIDRLEGYKKALIECNLSYNTDY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVRQPSYDIGYKASEILINCLKGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            26882..27775
                     /gene="rbsK"
                     /locus_tag="PC592_001622"
     CDS             26882..27775
                     /gene="rbsK"
                     /locus_tag="PC592_001622"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDF4055599.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCVGEDSLGEELIRNFRTNKVDYSLVSRNKHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRINVL
                     LNPAPAIKLDEDIIEKVTYLTPNEHEYKIVFDTNEEIEEVLKKYPNKLVITEGKNGAR
                     FYDGNEVKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEEVEKYLNNNK"
     gene            27823..28785
                     /locus_tag="PC592_001623"
     CDS             27823..28785
                     /locus_tag="PC592_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF4055600.1"
                     /translation="MKVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGASDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            28838..30349
                     /locus_tag="PC592_001624"
     CDS             28838..30349
                     /locus_tag="PC592_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF4055601.1"
                     /translation="MSNIILKLSNIAKEFPGVKALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFQDKEIENISPDVSKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDVNPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLIKDLKDSGVSIIYISHRMEELFEICDRITIMRDGK
                     TVSTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDVSFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALRIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGNLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            30333..31331
                     /locus_tag="PC592_001625"
     CDS             30333..31331
                     /locus_tag="PC592_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDF4055602.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSAFRDQGSAAVGLVIIFIIMSIAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWLGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYVGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKLAKSK"
     gene            31515..32777
                     /locus_tag="PC592_001626"
     CDS             31515..32777
                     /locus_tag="PC592_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF4055603.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGIADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEHNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGINAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNVHKILEETLGRSLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            32797..33540
                     /locus_tag="PC592_001627"
     CDS             32797..33540
                     /locus_tag="PC592_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDF4055604.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDYNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     VDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            33713..35098
                     /locus_tag="PC592_001628"
     CDS             33713..35098
                     /locus_tag="PC592_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4055605.1"
                     /translation="MSDLNKKFLIEYIDEIQEELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKHDFSIDELEGMDTAFVASYGEGEPVIAVLGEYDALDGLSQKVSITKEPILDS
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDSCRVHYVTTNGGKMPNIVPDFAEVWYYIRGIKMEHVRDVFDRIVDIA
                     KGASLMTGTSMEYDIISGVYDYIPNTILTDILSQNMKLIGVQNYNEDDYHFAEKLAET
                     VSIDKRISVSSVLSGNKDITKMNLHGEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSIACSINDVMLDEVIINKAKKELKN
                     TIGSFEYIPII"
     gene            35310..36149
                     /locus_tag="PC592_001629"
     CDS             35310..36149
                     /locus_tag="PC592_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055606.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDRRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFAYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYMNILESRGGK
                     NVQ"
     gene            36139..36582
                     /locus_tag="PC592_001630"
     CDS             36139..36582
                     /locus_tag="PC592_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055607.1"
                     /translation="MYSNTYNNEHFMRARAFIENNEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            36593..37084
                     /locus_tag="PC592_001631"
     CDS             36593..37084
                     /locus_tag="PC592_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055608.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIALGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVFSSFIGYYNNRLRKML
                     FKK"
     gene            complement(37286..38014)
                     /locus_tag="PC592_001632"
     CDS             complement(37286..38014)
                     /locus_tag="PC592_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF4055609.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            38139..39227
                     /locus_tag="PC592_001633"
     CDS             38139..39227
                     /locus_tag="PC592_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055610.1"
                     /translation="MNFNFAKATNSRLMGSLGLMINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLKNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYNKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYDKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNIVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSDMNEGIFF
                     TRFNFNNDHVKENVYVINNDMKAIYYLMGNKFFIGTYDENDCNYINEISQSNYSDYIK
                     FEENFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(39665..40555)
                     /locus_tag="PC592_001634"
     CDS             complement(39665..40555)
                     /locus_tag="PC592_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055611.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQGELRNDPQISN
                     GYTKVPNNQNINNLYPNNINNYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNS
                     NMGTPNNMSNNMNSNMGIPNNMPNNMNSNMGIPNNMPNNMNSNMGIPNNMPNNMNSNM
                     GIPNNMPNNMNSNMGIPNNMPNNMNSNMGIPNNMYGNMNNNMYGNTGMPNNMNSNMGY
                     NMNNTMGIPNFSCNQNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSN
                     MSMQGIPQATNIEEFDEEEM"
     gene            40755..41120
                     /locus_tag="PC592_001635"
     CDS             40755..41120
                     /locus_tag="PC592_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4055612.1"
                     /translation="MREEINDCNCNIIHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            41143..43530
                     /gene="cadA"
                     /locus_tag="PC592_001636"
     CDS             41143..43530
                     /gene="cadA"
                     /locus_tag="PC592_001636"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDF4055613.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINDKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDATIEKIIDIIDSTEPGLDIQINSKENASNKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTINISNNFEEDDVINKIKEIINSTEPGLD
                     IQVWSNDKVKERTTEKSGVANDTNKKELISLIIGVLVYIFGIYQTATGYESQFSNIVF
                     IVAYVIIGGDVVLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVKVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFIPPLVIPGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGKFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIKSLKAIGVKEVVMLTGDNEKVAKNIARELELDTVYSNLLPNEKVDRLEELYEGRT
                     EREKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKMIVMILGAGGVATMWEAIFADVGVSLIAVVNAMRAMR"
BASE COUNT        17358 a         4469 c         7911 g        14231 t
ORIGIN      
        1 ggggatggcc tgtggagaat taataagaca tattttagta cgcaaaattc tgtgaagcag
       61 gaaccctgtg actttagtca tgggaggttc aggaggctgt agaaagtttc tataagagtt
      121 cactttgtga aaaaactgct ctgtgtgaaa agtatataaa catgcttaca tctgaggagt
      181 ttttaatttt ctttgaaagg tacaatcaac ttataaggtt aataaacaag ggtatgtata
      241 aagaagctat acaagggttt aaacttataa ctgagcaata ctgtgattta atagaacctt
      301 atgagttact tgccttactg tatgacaagg aagaagaata tataaaattt gatgaatgtt
      361 tagaagtatt gaatactatt gataaggaaa actatttatt aaatcaagaa aataatacac
      421 tagatatgta taatagtact aatatacaaa ctaaaagtaa tgtaaaagta gatgattata
      481 agaatgagtt tttacataaa agtagtaata accataaaat tgatgattat aagaatgtaa
      541 ctaaagaaaa gagttcaagc ataaaccaga aaaattcaga ttctaataag aaaaaaagta
      601 ttaaaaaaaa taaataccta tatatagcaa tagtattagg aatattatta ataggacaag
      661 gtatatatag ttcttataag atgaataatt taactgataa aatatctaaa aataatgaaa
      721 ctaaaaatga agagtcaaca gattctagtt tggctaagaa agaaaacaat atagaagaaa
      781 atgaagatat gaataagact tctaatatcg ataagagtaa taaaaatatt aataaagagg
      841 atataaaatc taaaaaaaat actgtagaga atgaagatga taaagattct gacttattta
      901 cagaggatga attgatgtct aaggcaaata ctttaaaatc agaaaagaaa actaaatctt
      961 ctatacaact atataagaaa gttgcagata taggtgaaaa taaaggaaat acatctgaag
     1021 caacttatca agttgctatt cttagtgaaa agttaaaaga ctataaaact gctgaagaat
     1081 attataaaat gtatgtggaa aattactcag aaaaagatgc ttattttgat gaatcttatt
     1141 ataacttagg tatgatgtac tataacaatg gtgatttaaa aagttctaaa ttgacattaa
     1201 agaagttggt taataaggtg ccaaatagta tgtataataa ttcaaaagta aaagaaattt
     1261 taaaagaaga atagctaaat tagataagaa aaataaatta ttttatttta aaataatatg
     1321 attataatat attgacatac cattttaaaa aatttaaaat attaattata aaatgaggag
     1381 ggataaaaaa tggagtttga aaaagggagt atttcaattc atacagaaaa tatttttcct
     1441 ataattaaaa aatggttata ttctgataaa gacatattta taagagagct tataagtaat
     1501 ggatgtgatg cagtaagtaa acacaaaaga cttgtatcat taggagaaat atcagagaat
     1561 aagtcatcag attacaaaat tatagtatct gtaaataaag gagaaggtac gcttaaattt
     1621 attgacaatg gaattggtat gactgaagaa gaaataaaaa aatacataaa tcaagttgct
     1681 ttttcaggtg ctgaagattt ctttaataaa tataaggata agatggaaga gtcaaatgac
     1741 ataataggtc attttggatt aggattttat tctgcattta tggtgtctaa aaaggtacaa
     1801 atagatacac tttcatatac agaaggagca actcctgtaa gatggatatc tgaaggtggt
     1861 acagaatacg aaatatctga atcagatact agaaatgata gaggaactac tataacacta
     1921 tttattgatg atgatagtaa agagttttta gatgaattta ctgtaagagg gataataaat
     1981 aaatactgtt ctttcttacc agtagaaata tatttagaag atgttgaaag attagaaaga
     2041 gaagctaagg aagcagaaga aaaagctaaa aaacaaaagg aagatggaaa agaagaggtt
     2101 gtagatgcaa aagtaattga gcctttaaac gacactaatc cgctatggtt aaaatctcca
     2161 aaagattgta ctgatgagga atataaagag ttttatagaa aggtattcca tgtatttgat
     2221 gagcctttat tttggataca tttaaatgta gattatcctt tcaacttaaa gggtatactt
     2281 tacttcccta aattaaaaaa tgagtttgag ttgactgaag gaaaagtaaa attatacaac
     2341 aatcaagtgt ttgtggctga caacataaaa gaagttatac cagaattttt acttttatta
     2401 aaaggtgtta tagactgccc agacttacca ttaaatgtat caagaagttt cttacaaaat
     2461 gacagagacg taagtaaaat ttctaaacat ataattaaaa aagtagctga taagttaaaa
     2521 tctctttgta aaaatgaaag agaagaatat aataaatttt gggatgatat acaaatattt
     2581 attaaatacg gttgcttaaa agatgaaagt ttctatgaga aggtaaaaga atgtatatta
     2641 tttaaaacta ttgatgatga gtatataaca ttacaagatt atctagaaaa atgtaaggac
     2701 aaacacgaaa ataaggtatt ttatgtaagt gataaggagc aacaatctca atacattaaa
     2761 ttatttaaag aatacgactt aagtgctgtt gttttaaact catcaataga tactcatttt
     2821 atttcattta tggaatataa agaaaatgga gttaagttta atagaataga tgcagacctt
     2881 tctgatgtat taaaagataa aaatgaaaat aaagatagtg aagaaaacaa agaagagata
     2941 gctaagatag aaggtctgtt taaagaaact gtcggagaaa gagtaaagaa ttattctgta
     3001 gaaggattga aaaatgaaga cactccagct atggtgttag tatcagaaca atctattaga
     3061 atggcagaaa tgcaatcaag atttgctgga atggatttag gaatgaattt tgaggaagaa
     3121 aaaactcttg ttataaatga gaacagtcca ataatcaaaa aattggtttc tcttaaagat
     3181 gatgaggaaa agaaagataa ggttacgctt atttgtaatc agatagcaga tttagcttta
     3241 ctttctaata aagaattaaa gccagacgag ttagattcat ttgtccaaag aagtaataaa
     3301 cttatgagtt tgttgataga attataaggt tgaatttgaa tacattgaag taaatttata
     3361 aaaagtattc aatatcaatg ataataaaga ggtgtctcaa agtgaacttt ttagttcatg
     3421 aggcactttt tttatgtgaa attaaatgta ttttaatcgt ttcaataatg aaaaagaaat
     3481 ttatctctat ttttagacag actatttttt atatttgatt aatttttaaa tatttaagta
     3541 ggttctaata aaaaactcta tttagttaaa tatagttaac ttgatatata ataaaataat
     3601 acatataatt aagtaaaaga ttgtttttta gtttatgttt aaatacataa ttaaattttg
     3661 ttaaaaaata aaattattaa taaaatagaa ataggaggta ttagcatgaa ttttaattat
     3721 aatttgccag taaatatctt atttgggaga ggcagaatta atgatgtggg aaaagaagta
     3781 tccaaatatg gcaaaaaagt attgatagta acaggtaaaa atagtacaaa aaaaactgga
     3841 ttacttgata aaacaataga tttactaaaa gactctaaaa tagaatatga agtttttgat
     3901 agagtagagc aaaatcctct tataactact atatattcag gagtagaaat tataaaagca
     3961 actggatgtg attgtgtttt agggcttggt ggaggaagta ttatggatgc tgctaagagt
     4021 atagcttttt cctataaaaa cccaggagat ttaaatgatt atatatttgg aattagacaa
     4081 ggtgaagaag ctttacctat aatcttagtt ccaactacat caggcacagg tagtgaagga
     4141 aattgttttg cagtacttac aaattcagaa actaaagata aaaaatctat aaagaagaat
     4201 agtatgtatg caaaatcatc aataattgac ccagaactta tggttacaat gccaaagcat
     4261 ataattgcat cagttggatt tgatgcactt gctcataata tggaagcata tctttctaat
     4321 ggaagaaacc ctattgcaga tgtacaagct atttatggga ttgaacttat atcagaaaac
     4381 ctagtaaagg tatataataa tgttaatgat ttagaagcat gggaaaaaat aacacttgca
     4441 agtactattg gaggaatgac gattggtaca gcgggaacag ccttgtcaca tggtatggag
     4501 catcctgtaa gtggtcttag agatgtaatg catggaaaag gacttgcagc tttgactcct
     4561 gttattatag aaagttcatg ggatagtgat actgaaagat ttgggaatat ttctaaaata
     4621 ttaggaggaa cttgtgcaga agattgttca gatgcaatta gaaattttct taaaaaaata
     4681 gatttggata taaaactaag tgatttaggt attgaaaaat cagatataga ttggttaact
     4741 gataattgta tgaaaatatc agttgcaaat attaagagac atccaaagta ctttaataag
     4801 gaagaaataa aagaaatgta ccgtaaatct ctataatctg attttacata tttaacttta
     4861 aataaaaatt ataaattaat aataaaaaat ttataattaa tcaatagcaa aaaaattgtg
     4921 tataggaatt agatacacaa taaacttgtc ttaagctttt attttacttt ctaataaata
     4981 aaggagttta aaaaagggaa gattaattaa gtaatatttt ataaaagtct tcgatttaaa
     5041 aactttaagt agaggtgaaa taaatgttta atcccaaaag aataatattc gaaaaaggaa
     5101 ctttagacac tgatgtgggt aaaaatatat acaataaatt taaagataat aaagatgtag
     5161 agataattaa tatatcatca aatagaatta aagaacatat tccaggtgaa aatctatatg
     5221 aacaatatag aagtgggaag cagactatgg tggttgggat tagaaaaagt ctgaagtttc
     5281 aaacatgtaa accttctgct aattaccaac taccacttgt cagtggatgt atgggaagat
     5341 gtgaatattg ctatttaaat acacaattag gtgataaacc ttttataagg gtatttgtaa
     5401 atgtagatga aatactagaa cagacaaaaa aatatattga agatagaaag ccacaggtaa
     5461 ccatatttga aggagcggct acatcagacc cagttccagt ggagccatat actaattcct
     5521 tgaagaaaac aatagagttt tttggaaaag aagaaaaagg aagatttaga tttgttacta
     5581 aatacagtga tgtagatagc ttattagatg ccaaacataa taatcataca gaaatacgat
     5641 ttagtatcaa tactcctaga attataaacg aacatgagca ttatacagca tctgcaaata
     5701 aaagaataga gtcagctgta aaacttgcta gggctggcta tcagattggt tttataatag
     5761 cacctgtgtt tttatatgaa ggttggaagg aagaatataa aaatcttatt agaagtataa
     5821 aagaagcttt accaaaggat tttgataaaa aaattatatt tgaagttata tctcatagat
     5881 atacaactaa agcaaaaaat agaatattag agatttatcc agatacacta ttaccaatgg
     5941 aaaatgaaga tagaaagttt aaatacggtc aatttggata tggtaagtac gtgtacgata
     6001 aagaacaatt agatgatatg aaagagttct ttcataagga aataaatgga gtatttaaaa
     6061 atagtttaat aaaatatata atatagcaaa tcttatctaa agatttgcta tattttattt
     6121 ttataataaa gtgatgagtt ttagtactat aatatgagaa aattaaaaag ggcactatct
     6181 atcaagaaca ttttttctag ttttgatact ataaaggata agagtaacaa aaatatcagg
     6241 aggagttata atatgcatgc atgggagtct attcaaatta cgttggattt aatagaagca
     6301 aacttatcag aagaaatatc aattaatgaa ttagcaaata aagcaaactt atcaccattt
     6361 tactatcaga gactatttaa aagattggta aataagactg taatggagta tataaagctt
     6421 cgtcgtcttg caaaagcttc tgaatactta gcagaacata agaatcgtat acttgatgta
     6481 gctttaaaat ttggatttgc tagccatgag acatttacac gttcctttaa aaaagcatat
     6541 ggattaactc cagaaaaata tagagcaaat ccagtaaaac tcaatcactt tattaagcca
     6601 gaattaattt taaattatgc tatggttgat gaaggtgttc cactgattgc agatgatata
     6661 gtgattgaag tcactcgtaa gacattgagt aatccaagga cgtttgttgg aatagaaatg
     6721 gaagtaccta tttgccagtt ggtgggcggt gaaacaactg gtattgcaat agtagaggaa
     6781 ttatggatga aacttggaag tcaaagacat aatataccaa atcaaattcc aggtggaaat
     6841 gaatttgctg ctctttatat gggaaatgca aaagaaggaa attgtatgta tatggcaggt
     6901 gtagaggtag aattagggac atcagtagaa ggatatagta cttttgagtt accagctaaa
     6961 gaatatttag tatgtggatt tgaggcagaa aactttaatg agttagttaa ttcagctgtt
     7021 tttaaagcgg ataaatttat ggaaagatgg atgaagaagc ataatttaac aactgctgat
     7081 tttgcaattg agatgtatta ccccactaca cctgaagtag catatctgga gcattggatt
     7141 gttccaattc ctattgaaca atagaaagga tgatgaatat gaattggcaa gatacgtttt
     7201 ttcaagatac taaacctaca tttgagcaaa ttaatgaatt tattaataat ccattatggg
     7261 acaagttaaa taaaactttg gtttctactt ataatgtaga acctaagctt gaatacagta
     7321 aatgttcaat gcaaagaggc tggaatgtaa aatacaaaaa aagaggtaaa tcactatgta
     7381 ctttatatcc acaagaaggt tattttaaag ctttggttat tgtaaatgaa agcaatagag
     7441 tagaggttga tttatttatt aatacttgtt gtgattatat caaacaaata tataatgaag
     7501 taaaattttt taatggtggt aagtggttaa tgattcaagt agatagtttg ttggtattaa
     7561 acgatatgct tgaactaatt aaatttagaa tataaaatat aaaacaggat gaatatataa
     7621 gtcatcctgt ttttatattc aatcagataa attaatatat agactatagt ataaataatt
     7681 tagcaaattt aaatttactt tgtttttcta cattccttgc aattaagtcc acatttattt
     7741 ttttcttgca tattggtagc accccaatta gcaaattgtt gtaaaatagg tacaatactt
     7801 ttgcctttac ttgttagtgt atattcaacc tttggaggaa tttcattata ttgtttacga
     7861 tgaacaatac catcagactc taaatctttt agtgattgag ctagcatagt gtttgtaatt
     7921 ccatctaatt ttctttttat gctactatat ctaatgggat tttcaactgc taacatacat
     7981 ataataggta atttccactt accaccaaca atatctaatg cataacgaat tggacaggtt
     8041 aattcttcaa catttttagt tatatttttt tcactattta tacccatttt aattactcct
     8101 tagttataat agtatctttt ttatacttta taagaaaaaa ctgcatactt gttttttctg
     8161 tattttatat taaaattata tcaaaggata atccttaata caagtattta aaaggggtgt
     8221 aagaattatg aaagcattag aatttttgaa caaggcagga gtttattatt tagcaacagc
     8281 tgatgagaac aatcaagcac atgtgcgtcc tttaggattt gttatggaat acaatggtaa
     8341 acttacattt tgtacatcta atcaaaagga tatgtttaag caacttattt ttaatccaaa
     8401 ggttgagctt tgttgtatag accaaaacct taatactcta cgtattttag gtgaagcagt
     8461 atttgttaca tcaaaagaaa cacaagctaa agcacttgaa ataatgccaa gtttaggtca
     8521 gatgtactct gtaggagatg gtaagtttga aatattctct attgataagg caaaagttag
     8581 ttgttgttca atgagtggta aaaagattga tgtagaactt taattataat tgaatcgata
     8641 cacatagtga aaattgaaaa aacgttatca ctgaaatatt gaagatttaa ttaaaatgca
     8701 ataaaatgtt tttaaataat gaatggataa aaatttttag ttattagatt tgtatttcaa
     8761 taatgatatg ttattttgaa taattacata ctagaaataa gggcaatcaa aatttatttt
     8821 ataattggct agacttcttt taaaaaatat tttaactata attgattttt atttaatcga
     8881 aaaaaatatt atgactataa aaaattgcta cttattgttt gaatattttt gtatataaat
     8941 aataagtggc ataaatttat atattaataa tgatataata taaattaata gataagatat
     9001 aattttaaaa ggagtgatat aagatgagca aatatagttc tttatgggaa tatgttaaga
     9061 aaaacaatag tcaatcgttt aaattaactt ttgaagaaat aaaagatatt gctggagtag
     9121 agatagacca ttcgtttttg aaatataaaa aggaattaaa tgaatatgga tatcaagtag
     9181 gaaaaatctc tttaaaagag aagactgtta ttttcgataa aattggttaa gacataaata
     9241 attacatata ataaaataat ttgtattgac aactattaaa aataaagtaa atcttatata
     9301 agatttactt tatttttaga ggctgctttt tttaacttta tactataagg tatataaaac
     9361 taagcctatt aaaaatgtta taatttctat tgctatcata gaccatatca atccatcaag
     9421 ttcataaaag taattaatct ttattaaata gcttctttat tataatttct ttatttcata
     9481 taatataaat agtattaaaa tttttatgag agttagagta agcatgtatt actacttaaa
     9541 tatttctata atcaacatct agtaatttac ctttttggtg aaaatgatta ataagttttt
     9601 tgggatgatt cattattaat tcatctggaa aattaatttc ctttaagata ttctcagaat
     9661 actcatagtt acctatgtca aaacaaatgt gagcatctga agttagtatg attttagcac
     9721 catatttttt gcaaagcgta gcaatatact tacagttatc cgagctacca tttcttgaca
     9781 ctcctttaat agaacaatta tttatttcta ttaagatatt cttttctata gctaatttaa
     9841 tgattaattc atagtcgatt gggtagtttg ggtttccaag gtgtcctaat atttcaatat
     9901 tatcatgctt atttattgca tttattaagg ctttagtatt attctctaat gtatttggtg
     9961 aaaaaacggc ttcgtgaaat gacaagataa gataatctaa tcgaggaatt acaaaaggct
    10021 ctaggtctat gtttccttta gtgtctagta tatttgcttc acatcctctt aaaattataa
    10081 tgttatttat gattcttggg atatttttaa tgttgtgaaa gtaccatctg tggggagaac
    10141 caggcatctt aggaccatgt tcagatgtac ctagtatctt aattccattt tctttacaat
    10201 aattaatatt ttctaacaaa gtgctatagc catgaccact gactatagag tgggtgtgta
    10261 aatctgataa aaaattcata taaattcctc ctctataaaa gatgagggta acgtaattta
    10321 tattataaaa cgaatagaaa agaaaatcaa tagttacata attagacaaa aatattaaaa
    10381 tattgtagaa ttaagcttaa taataaatgt ttaacagtat tactgcttat aggggagggt
    10441 aactatgaca caaagaaagc tatcaaggaa agaaaaagtt ttaatttgct tgaaaaggtt
    10501 aacagaagaa cacttgaact ttaataatgg cattagattt ggatttgatg cagaatatat
    10561 tgctactgaa gtaggtataa atagaagtaa tgctagtaag gaattaaatc aattaataaa
    10621 agaaagtatt attataaaga taaagggaaa gcctgttcaa tacttataca aagaaagtat
    10681 tgagagcatt ttaggaaaga aactaaataa agggatattt agtaatatta actctataaa
    10741 tgaatatagt gaagatgatt ctatcaaaga tgagtatatc ttagaaggta taaaaaaaga
    10801 gaacaatatt tttaatttag taggatgtga tggaagttta aagtcccaaa tagaacaggc
    10861 taaagcagca gtaatatatc cacctaaggg gttgagtaca ttaataatag gacctacagg
    10921 agttggtaaa tctatatttg cagaatatat gtataagtat agtttgaata taaaagaaga
    10981 tagtgataat gcaccattta tcatatttaa ctgtgctgat tattctgata atcagcaatt
    11041 attgttagca cagctttttg gatatgtaaa aggagcattt actggagctg ataaagacaa
    11101 gtatggtatt gtgcatgaag ctaataatgg gatattgttt ttagatgaag ttcataggtt
    11161 atctgcagag ggacaagaaa tgctatttct gcttatggat aaaggtatat atagaaggtt
    11221 aggagaggct aataaggtac atgagtgtag ggttatgata attgcagcta ctacagaaga
    11281 cccagaaaca gcaatgctgg aaacgttttt aagaagaata cctgtaacta taaagattcc
    11341 gtctttagag gaaagaggtt ttcaagagag aatgaaactt atatgttatt tttttaaaga
    11401 agagagtatt aggattggtg ttaagttaaa ggtttcaaaa gaagttatta aggcatttat
    11461 tttatataag tgtaagggaa acataggaca attaaaaagc gatatacaat taatttgtgc
    11521 aagagctttt ttagattata tgacctataa aagggaatgt gtatatgtaa ggctctctct
    11581 tctaccaaac aatattagag aatcattata tggaaataat agaaaagagg agtttgtaca
    11641 aaatttcagt tttattggga aagatgatat tattttttta ccagaagaaa agagttttga
    11701 aagtgaaaat ttattaatag aaaataaaaa atatgattta gatttctatg gaatgataaa
    11761 agaaacttgg aataaacttc aacaagaagg tattaaagag tcacaaatta gaagtgttat
    11821 agatgaagat atacagaagt attcctacaa tttaatgaat acttttatct ataatagtag
    11881 taatcaaaca gcttataaca acattgttaa tgattcaatc gcaactactg tgaagtatgt
    11941 tttacaaaag catgataaat ggagcaaaag agaaggatta gataaattaa taaaagctat
    12001 agccttacat attcagaatt taattgaaag aataaagatt gggaacatag taaagcatcc
    12061 taataaagat gaaattatga aggaaagagc atatgaatat aacatagcaa aagaaatatt
    12121 atctaacatg tcattaatgt atggagttga gtttccagaa gatgaagcaa tttttttagc
    12181 aacgtttctt tatttatctt atgtgggatt aaatgaggaa agtatagcaa tattagtcat
    12241 aatgcatggt gaatctacag cctctagcat ggtgaatgta gctaatactt tactggattg
    12301 taaccatgca gtggcaatca atatgggatt agaagataga gttcaggata ttttagtaca
    12361 agctgtagaa atagccaatg aaattgacaa aggaaaggga attttaatct taaccgatat
    12421 ggggtctatt ttaacatttg ctaaagttat tcatgatgct acaggaaaag aagtaaaagc
    12481 aatagatatg gtaagtacac ctattgtaat agaagcaact agaaaggctc taactccaga
    12541 aatgacatta gagaaattat attttaatat tatagaatct ataaagaaac attatggaga
    12601 tatggaaatt acatatgctg aaaaagataa tggtggtaga tattttgata gattactaat
    12661 tgataatatt agtaaaactt tgactttttt aaacggggaa aaggcttatt ttatattaaa
    12721 agaagtaatt aatagaatta gtgaacatta ttctttagta attcaagatg agcttttagt
    12781 aaagtttata tttcattgtt cctgtatgat tgaaagagta ataataaaag agtctttagt
    12841 ttataaatca tatgaagaaa gaattagtag aagtaaagaa ttatatttag ttataaaaga
    12901 aagttttaag ctagtagaag agacattcga tataattatt tcagatatgg aatatgcaaa
    12961 tatattagat atatttgaat cacaatatga tacagataaa ttcaaaagtt gatacaaaat
    13021 ttaaaaatag ccaaaaggct atcttttttt tacttttttt gatacagatt tgatacaagt
    13081 tggaaaaatc ttttgataca tattgatata gtaagttttt taaaaaattt aagcaaaaag
    13141 gtttgattaa atcctgtaaa atagccattt gttattgata cacataagtt ggcacggcaa
    13201 ttgcttgtat aaaaaatgac aagaaaagtg aggtgaaatt ggtgatagga ataatagtta
    13261 tgactcatgg gagttttagt gaagaaatta taaaaagctg tgaacttatt gcaggaccag
    13321 cagaaagaac agcagcaatt aaactaaata ggaatgataa tattgaagac ttaaataaaa
    13381 attttgtaga aaagttaaat gaactagatg aaggtgacgg agttttagta ttagctgacc
    13441 tattaggagg ttcgccaagt aatgttgcaa gtttaaacct taaaaaaggt ggaaagtttc
    13501 atgcacttac tggagtaaat cttccaatgc tacttgaagc tttaattaat agagagggaa
    13561 aaagtttaga ggagttagca gaagcatgta ttgaagcagg acaaactggt ataaacaata
    13621 ttaataaagt tcttagctca atgtaataga aaaaggagtt tgattaaaaa tgtctttagt
    13681 aaaatattgc agatgtgatg atagattaat acatggtcaa gtgatatata aatgggttaa
    13741 gcatctaggt gtaaaaaaga tagtagtagt agatgatgaa accaccaatg atgttattgc
    13801 taaaggtttg ataaaaatgg cagcaccaaa gaatattgat ttatcaatat taactgtaag
    13861 tgaatcaagg agatattttt ataataatca agctgatgat aacgtttttg tattaattaa
    13921 aaatttagat actgcaaata gaatgataga agaagggatt aatatcaaaa aacttattgt
    13981 tggaagaata cctacaggaa taggaaaaaa gaaaatatct caaaatgtat acattaataa
    14041 aaaagagttt cttttaatag atgaatttat taaaaaaaat attaatgtat caattcaaat
    14101 ggtacctgac gaagaagaaa tagaattaaa ccacaatatt aatcgctata aaggagagtt
    14161 tatttagcaa tgaataaata taaggtaatc atactctgtc atggaacttg gggaaagtta
    14221 ttagtagaag aaacaaataa aaactttgga ttgtcaaatc aatatgaagt tttatcatta
    14281 agttctgaaa aagatgtttc tgtattcatg aaaggggttg aagaagcagt agataaagaa
    14341 gatgtgaaaa ttataatatc agatttatat ggagggtcta catcaagtgt tgcaatatct
    14401 gttgctataa gaagaggaat agatgcaata aatggactta gcttacagac aattttaatc
    14461 gtagatgagg aattaagtaa agaagataaa ttacatacat taccagaaag aatagtcaaa
    14521 aaaaataata atctttgtgt ggatttaatt aaagagttta aaaaaatata aattatgagg
    14581 tgaatataat ggcaaaaata acattagtaa gagtagacca cagattaatt catggacaag
    14641 ttataacaaa atgggtaaaa atcgctcaag ctcaaaaaat aataatagtt gatgacttct
    14701 taggtcaaga tgaatttatg gctgacatat ataaaatggc ggcaccatca ggagtggaag
    14761 tagttatttt aacagcagaa gatgcaggac aagcattcca aaacaacact ttaggagata
    14821 aaaatatatt tattctattt aaaaatgttg atatggcaaa taaggcttat aaagctggac
    14881 ttaaatatga aaagattcaa ttaggaggta ttccaaatga agcaggaaag aagatggtat
    14941 ttacagctgt ttcattagga agtgaagata taaaacaact taatgaactt aatgaaaatg
    15001 gagttgagat agtattacaa gttataccag aggaatcatc tatgacatat gaaaatgcat
    15061 taaagaaatt taaataaaaa atataaatta ggaggaatta taaatggaat ctgttttgat
    15121 gttggcaatt gtaacaggat tatggtattg gtttgcagca ggtcttgcag ggtataccct
    15181 tttctcaaca ctaaagtctc ctttatttat aggttttagc cttggattac tttggggtga
    15241 tgtaacaact ggtatgattg ttggtgcaag tatagaaatg gtttatctag gaatggtcgc
    15301 agcaggagga aatattccat cagataaatg tctagctgct cttattgcaa taccagtagc
    15361 acttcaaact ggtgttaatg cagaagttgc agtatctatt gcggtacctt taggcgttat
    15421 aggagtatta gttaataact taagaagaac tggtaatgct gtattagttc ataaggcaga
    15481 taagtatgct gaagaaggta atacaaaagg tatctggaga tgtgcaacac tttattcttt
    15541 gatatttggg tttgttttaa gatttccaat agtttttgta tgtaactttt ttggagcaga
    15601 tttagttcaa tcattattaa atgttatacc acaatggtta atgaatggat taacagtaat
    15661 gggaggtata ttacctgcat taggttttgc aacaacaata tttactatag gtaaaaataa
    15721 attcttacca atgtttatta taggattttt tatggttcaa tattttgaaa tatcaattac
    15781 tgcagctgca atatttggtg tttgtatagc tcttttaatt acctttatga aagaagacaa
    15841 aagggtaggt gaagtataat gcaagaaata aaaaataaag acgttaaaaa tggacaaggt
    15901 acaactgaag ttaataagac aagagtactt acaaagaaag atgtaacaaa aacataccta
    15961 agatggtggt ggacagcaga attatctaac tcttttgaaa gaatgcaagc attagcagtt
    16021 tgtgcaagtt tcactccagc tttagaaaag ttatataaga aaaaagaaga tttagtagat
    16081 gcgttaaaga gacacttaca attttttaat actcaagcta tatggggagg gttaattcac
    16141 ggtacagttt tagctatgga agaagagaaa gctactgaag gaaaaatccc aggagaggtc
    16201 atttcaggtg ttaagaatgg tcttatggga cctttggctg gaattggaga tactttagat
    16261 tttggtacat ttcaaacaat attcttagcg ttaggtgctt catttggagc agaaggaagt
    16321 gttataggtg catttttccc aataatcttt agtatattac tattttgcga aggttattac
    16381 ttattccatt taggatattc tttaggtaga gattcaatta agaaaattct atcaggtggt
    16441 attgtcaata agataattga tggcgcttca attttaggaa tgtttatgat gggagcatta
    16501 tctgcaacta cagttaagct ttcaactccg ctatcatttg atattggtgg taaagcaatt
    16561 gttgttcaag atacattaaa tatgattgct ccaggtttat taccacttag tgttgtattc
    16621 ttcgtatatt ggggaatgaa atacaagaag tggacaataa ctaagttatt agtaatttta
    16681 gttgtattgg cattagtagg atcattcatt ggaatattct aatttacaat gattaaaata
    16741 tagaatttaa ttttaggagg agaaagaaat gtcagaaaaa atgtatacag aaaaggaata
    16801 tttagaagga attagaggag caacaggaga aagagcagta tggttctatc ttcttatgaa
    16861 agaagctgaa aaattaggag ttaatccaga tgatatatgt aaagaagcaa tatatggatt
    16921 tggtaaaatg agaggtcaaa aatatagcgt agcagacact ccaggaaaaa tggcagaaat
    16981 gttatataac agtaaaggac aaaaagtatt tgaaatggaa ttagtagaaa atacagatga
    17041 gaatggagtt ttaaaattcc atcactgtcc attagatgca gcctggaaag aatatggatt
    17101 aactaaagaa gaaagaaaag aaatttgtag attagcttgt tacggtgatt atggaagagt
    17161 tgactgtgca caaagtgtta gattagagtt tgctcaaaaa cgtgctcatg atgatgaagt
    17221 ttgtgaatta gtattcacaa gaaaataatt tttaatgcta aaagcctgtt ctttaaggac
    17281 aggctttaaa aagatagaaa gtaggttact ttatggatat aagcagaaga gtagataata
    17341 gtttaaatag aaccatagaa tttctaaaag aattaataaa aattgactca caacaaggtg
    17401 aacctatttt acaatgtcct tttggtatag gacctaaaaa atctttagag aaaactttag
    17461 attactgtgc tagtttaggt tttagtgtta agaatattga taattatatt ggatatgcag
    17521 aaattggaga aggaaaggag ttaataggga ttccaatgca tttagatgta gttccaccag
    17581 gagacgggtg gagcgtagac ccattttcgg gagtagtaat tgacaatatt atttatggaa
    17641 gaggtgccgt agataataag ggggctgtat ctatgcttat acatgtattg aaaaacatag
    17701 aggatatgta ccctacaatt aataaaagaa taagattaat ttttggtaca aatgaggaaa
    17761 caggcatgga atgtatcaaa tattacttag ataaaggtga agaaatccca agtatgggat
    17821 ttactccaga tgctatgtat ccagtagtta atggagaaaa aggaagagtt catataagga
    17881 tagaaaaaga gattaaaatt gataaaagta aaccttacat aatattaagg ggaggaacta
    17941 aagaaaatgt tgttccatct cattgtactg caaaaattgt taatggaatt attttagagc
    18001 taaccactaa aggagtagct gtacatgcaa gtaatcctga aaagggagaa aatgctatat
    18061 ctaaaatggt aataaagata ttgaaagata atatgaattt tcagcataga gaagatatag
    18121 aattagtttc aaaatacctt tgtagtgact attatggaaa tgcattaggg attaatcgat
    18181 atgatggggt attcaaaaac actaccttaa atttaggaat attaaaagta aatgaggaaa
    18241 aaattgtatg tgagttggat ataaggtatg gtaaaaatat aattttaaac aatataatag
    18301 atagattcaa aaagtttttt tgtaatggtt ggaaaataga ggttattgcc cataaagact
    18361 tacattatgt ggatgagagt aatttagtac ttaaaaaatt attagaagca tatgaagaag
    18421 taacagatga aaatggatat acaattgcta tgggtggtgg cacatatgca agttggttta
    18481 aagatatggt ggcgtttgga cctaagtttt tagcgtataa aactggtggt catggagtag
    18541 acgaaagagt accaataaat catatacgaa agaatatgga gatatatacc ttggctttaa
    18601 taaaactatt agaattgtaa aaagagaaga gattttatgt gaaaatgtac ggatatctta
    18661 aaaagagaga taaaacgagt ttaactttat ttaaatgttc aacaccatca aatggggctg
    18721 tctcaaaata tagataagtc tcttccttat tgttgaaatg atgaatttta cttcatacaa
    18781 aaaagagtgt cttatgaagt aaaatgttca ttttgaaaca cactcatttg atgatgttga
    18841 agagaaaata agtatgaaat tattaaaaaa gatgatttta taaaagttaa ggttgaaaag
    18901 ttaattgaat ggaattagct aaatggagaa ggctatatac tatctaataa aataataaaa
    18961 aagtgttgta aaattggtta tatgattaga gaaaagtcta ttgatattta ttcagacagt
    19021 ggatgggaat ttatggtttg ggatgaaaat ggagaataat aaaaagtata gtttatacaa
    19081 tttaataaga tatatgtaca agcagttaat ataaatgatt gactgctttt cttttataga
    19141 tttttatata atagacaatt actaatacat gatagttgcc tattataatt ataagaataa
    19201 atacgaataa taattttata aaagaattaa atggaaaatt gaagagttat attcaggatt
    19261 ttaaaaagaa tatgaaatga gaaatgaaaa taaggtgctt tatattaaaa gatattttat
    19321 acaaaatatt taaaaacgtg ataaataaaa ctgtatttag atagattaat tactagtttt
    19381 atatagaata tggattttgt ttacaaaatt agaatatttt acaagttatt tttaaaaaat
    19441 atttaaatat atattttaga tatttgtttc tctgtggttg attttttcgt caaaagtcaa
    19501 cttcaaatcg cttgttagct ttatgtgttt aaggatataa ttatacataa ggagggattg
    19561 acatgaatga attaaacatc gcaaaaacgc tgattttaaa gcgtaaagaa aaaggaatta
    19621 cacaagatga acttgcaaat tatataggcg tttctaaagc ttctgtatct aaatgggaaa
    19681 ctggacaaag ttatcttgac ataacctttt taccgcaact cgcgacatat ttcaacatta
    19741 cagttgatga gttaatatgc tatgaacctc aaatgatgaa ggaagatatt aataaactat
    19801 acaataaact gtgcaaagac tttacggcta aaccatttga tgaagtcatg attgaaataa
    19861 gagaaatcat aaaaagatat tattcatgtt ttcctttgat ttttcggatg ggtcttttaa
    19921 tagtcaatca ctatgacatt gtagatgaaa aaaagcgtga actattaatt gatgaagcat
    19981 tggaaatatt tattcgtata caggaaactt gtaatgatat agatatttgc cgtcaagcaa
    20041 aaaatatgga ggcaacttgt tatatattgt taaatcaacc catacaagtg attgatttat
    20101 tgcaaaatag caattttccc atgataaatg aatctatact tcttgcacag gggcaaatga
    20161 tgaatggtca aattgatgaa gcaagagaaa catttcaact tggggcatat cagaatctta
    20221 tatcactagt tcaaaatcta gtgggtattt tgcaaaatgc agataaatta caaatgaaag
    20281 aaatagaaag acgtattcta gcaatttcaa atatatttga acttgataca ttatctcctg
    20341 ctactatgct ttctgcatat ttaacacaga cacaaattaa tttaatacat gaggataatg
    20401 aaggagctat taaatcatta cgaaaatatg tagatttagc aacaagtgat atatacccaa
    20461 ttacaataca tggtgatgac ttttttgata aacttgacag atggatttct gaaattggaa
    20521 taggtattac acgtgatgat acaatcgtaa aagcgggtat tgttgctgct attaaaaata
    20581 atccaatgtt ttctgtatta agtgaaaaca aagaatacaa atttcttata gaaaaattat
    20641 ctttattgga ggaataagat tatggaaaat ttgatggaat acttaccact tttgattcct
    20701 gttattattt tagatttaat tcttataatt actgcacttg ttcatgtatt gagacatcca
    20761 aattataaaa ttggaaataa agcaatatgg attattgtag tgctgtttat tagcataata
    20821 ggaccaattt tgtattttac aataggaaga ggtgaagaat gatgaatatt gtctcaataa
    20881 atgggttatc aaaaggtttt ggtaatcgaa agataataga taatctaaat tttactgtac
    20941 cagaagggtc agtctttggg tttgtaggta agaatggtgc aggtaagact acaacaatga
    21001 aaatggtact tgggttactt gaaccagata gtggaactat agatgtttgt ggtgagaaag
    21061 tgacctatgg aggaacaagt tctaatcgtc atgtaggtta tctgcctgat gttccagagt
    21121 tttacaacta tatgagacca cttgaatatc tttctctttg tggcgaaatt acgggacttt
    21181 caaaacaaga aataaagata aggagtgaag agttgttatc acttgtggga cttggcaatg
    21241 aaaagagacg aataggtgga ttttctcgtg gaatgaagca acgacttggt atagctcaag
    21301 ctttgctttc acgtcccaaa ttacttattt gtgatgaacc aacaagtgca cttgaccctg
    21361 ttggtcgaaa agaaatacta gatattatgc ttaaaatcaa agactcaaca actgtaatat
    21421 tttcaacaca tatactatca gatgttgaaa gaatctgtga ccatgttgct atattaaaca
    21481 aaggaagcat tgctcttagt ggtacacttt cagaaataaa aagtatgcac ggaaaggata
    21541 gacttttact ggagtttgca agtaatgatg aaattcaaaa gtttaagtct agtggtgaca
    21601 ttaaatcctt actaaaatat tcagaagaaa ctaatatgga aattgttttg catggtaaag
    21661 atataaaagc aatacaaaaa acagttatat ctacactcgc agaaatgaat ctttgtccag
    21721 taaagatgga actaatagaa ttgtcacttg aaaatttatt tttggaggta gtaaagtgag
    21781 agaatacata gcatttacaa aaaaagaatt taaggagaac ttaagaaatt ataaattatt
    21841 tagtttgatt attttatttt tagtatttgg aataatgagt cctctttctg caaaatttat
    21901 gccagacttg attgctcatt ttgctccaac tttaaaagtt actactgcac caactgcttt
    21961 agattcttgg acacagtttt ctggcaatat ttctggactt ggagcgagtt taactctaat
    22021 tgttttttgt aatattttat caaacgaata ctctaaagga acactcgtta ttatgttgac
    22081 taaagggtta tcacgttcat ctgtgatatt gtctaaattt tctattgcag taatcattat
    22141 gacaattggt ttttggttga gttttttatg tacttatgga tatacaatgt atttttggcc
    22201 aactgaaaat cttaatcata ttatattttc agcatttaac ttatggttaa ttaatattat
    22261 gtatattacc atattaattc ttgggtgtgt attatttaga ccagcatttg caagtgtgtt
    22321 acttgtatta gtagcaactc ttattttgag tttgatttct attcctaaac agattgcacc
    22381 ttatacgcct aatttcatat tatcaaaaaa tatagatttg gtttcaggta aagtggcagc
    22441 tccagaattt attattccaa tgattgtaac aattgttatt tcgataatat gtttgttatt
    22501 agctgtcatt ttatttaaga aaaaagcagt ttaaggatat ttttattatt aaatataaat
    22561 agtactgtat tatggaaaaa tgtgtttagt gttgtagaag aatatattta agtaaaaaga
    22621 ggttgtctca aaatagagat ataagcctct tttttattgt taaaattata aaaacatatt
    22681 tgatttcata caaaacaagt atctcataag ctaaaaaatt cattttgaga catttctttt
    22741 tttattttag tcattctcat tgtactttat aataattaag ttattacctt agggaattgt
    22801 ttaaaaataa aaaagagaag gattataatc taatgattat aagttattta agctatgttt
    22861 agtatataga gtctaaagta gtaaaggatt aaaataatat tgtttatatc aaataaagat
    22921 aagaatcttt aattgtggta aaatatacta aaaaatcact ttaaaagtga taaaattatt
    22981 ttaagtaaat attttaaagg ggtgtagata tggaaaagtc aaaagtatat ttttgtgatt
    23041 tatattcaaa ttcgcaaaat aaaaatgtac caaataatgt aagaagatta tttgataaag
    23101 caggattcaa ggatttaata gaaaagaatg accaagttgc aattaaactt cactttggag
    23161 aaaaaggaaa tactacatat atgagtcctg tggcagttag acaagtggtt gataaggtta
    23221 aagagtgtga aggaaagcca tttttaacag atacaaatac actatataca gggagtagaa
    23281 caaattctgt agaccatctt acaactgcta tagaaaatgg atttgcttat gcagttgtaa
    23341 atgcaccagt aataattgca gatggattat atagtagaaa ttatgagaat gtaaagatag
    23401 ataaaaaaca ttttgaaagt gtaaaaatag gtggagaaat ttataattcc tctgcaatga
    23461 tagtaatgag tcattttaaa ggtcatgaag cagcaggatt tggaggagca ttaaaaaacc
    23521 tagctatggg atgtgcaagt gcagcaggaa aacaaatgca acattctgat gttaccccag
    23581 tagtaaagga aaagaagtgt ataggttgtg gaaagtgtgt taattcttgt cctacaaaag
    23641 ctataagtat agtggataaa aaagcagtta tagattctga tgtatgttat ggatgtggag
    23701 aatgtccaac tgtctgtcca actagagcag taactataca atgggaaagt gactcagatg
    23761 tgtttgtcga aaagatggca gaatatgctt atggagcagt atcaaataaa aaagacaaga
    23821 taggatatat aacttttgtt atgaatgtaa ctccactttg tgattgtgta ccttggtcag
    23881 gtagaccaat tgcccatgat ataggaatat tagcatcaac agatcctgta gctattgaac
    23941 aagcatgtta cgatttgatt tgcaaggaaa tgggtcatga tgttttcaaa catgaacatc
    24001 ctcatgtaaa tggaactaga ataatagatt atgcatgtga aatgggtatg ggaagtaaag
    24061 aatatgaatt aataaaatta taagaatagt agtacttaaa tgcatataat tattgtaaga
    24121 gaaatctaaa agtatcaaag gagtatgcat ttatgaaaat ttactatgag aaagaaaaca
    24181 gcaagaaggc caatgtaaac aatattccaa gtgtatttgc gtttaatttt ctaagaaact
    24241 ttttgactag caaagagtat gaggaaacta gaaaagaata ttttataaat aatctaacaa
    24301 aaagtcaggt taatcaagct atgaaggatt taaaatggct atttagagaa tatgaaggct
    24361 tagaggtcat tacaatggaa agcttggatg gagttaagac aaggatagtt ttataaacta
    24421 gcaagaatta tattttaata aaaaatactg tttcaataat aatatgtata atccatgtac
    24481 taatattatt ttgaagcagt atttttttgc aaatagtaaa cttatacata aaataaagtt
    24541 gaccaataaa tattaagtat gtaatactat atataatagg taaactaaat ataggtatta
    24601 agttgacaaa taggagggta tatggaaaaa tacataataa aattaaaaaa taaagtattg
    24661 ggaggaaaag aaataagtta tgaagaagct cttaatttaa taagtcttga tacaaataat
    24721 aagaacgatt ttgatattct attaaaatct gcaaatgaaa taagagaatt ttttatggga
    24781 agaaaagcag atttatgtac gataattaat gctaaatctg gcaaatgtag tgaagactgt
    24841 aaattttgtg cccagtcatc tcattataaa actggtgtag aagaatattc attgttagat
    24901 tacaatgaaa tcttaaatag agctaaagag atggagagta aaggagtaca tagattttca
    24961 ttggttacaa gtggcaaagg tatgtcagga aaggagttta atgatatttt aaaaatctat
    25021 gaaagattga gggaaaatac taatttaaaa ttatgtgcat ctttaggaat tatagattat
    25081 gagcaagcta aaatgttgaa atcagtaggt gtaactacgt atcatcacaa tgttgaaacg
    25141 gctagagata attttcataa tatatgtaca acacacactt ataaagatag gataaaaacg
    25201 ataaaagagg ctaaagaagc tgggctagat gtatgtgtag gtggtataat tggaatgaat
    25261 gagagtgaag aacagagact aaaaatggct tttgaaatac gagaattaaa tgttaaatca
    25321 tttccaataa atattttaaa tcctattaag aatacaccaa tggaagatta tgatgtatta
    25381 gaaccaatgg aaatattaaa aacaacagca gtatttaggt ttataattcc taatgtatat
    25441 ataagatatg ctggtggaag gctatcatta aagggatatg atgaagttgg atttaatgga
    25501 ggagtaaatt ctgccattgt tggtgattat ttgacaactg ttggaaatgg cattgaaaat
    25561 gataaaaaaa tgattataga gcaaggattt gaaatttaat aaatattact taaattaatt
    25621 aatatacttt tagataatta taaaagtata ttaatttttt ttgtggatta atttaaatat
    25681 taaatttgaa ttataaattg caatattttg aaaaaaggga aaaatatcaa aatttatata
    25741 aaatagttgc aaaggaaaaa aagatgtgat agtatctagg taaccggtta agtaaaacgg
    25801 tttcctaaat tgtgggggtg aacttcttga gtataacaat aaaagaaatt ggcgaattgg
    25861 ctggtgtttc taaaacaact gtgtcaaaag tcattaataa taaagatgaa aacataagcc
    25921 aggcaacaag agaaaaaatt ttgaaaataa tgaaagaaaa aaattatgtg ccaaataaat
    25981 tagcacaaag tttagtaact aaaaaaacta atactatagg gcttcttata ccagatatac
    26041 gaaatccatt ctttacagat gtatcaagag gtgtagaaga taaagccaat aaagaaggct
    26101 acaatataat tttatgcaat acagatgaag atgctaaaaa agaatatgaa ggaataagaa
    26161 cgctatcaga gaggatgata gatggaatta tatttgcagc ctcttcaaat acaaactgga
    26221 aagaagcaaa ttataaagat ataaaaatac caactgtgtt gattgataag aagataagca
    26281 tgaacaaaga aaccttaaaa ggaattgtta aaataaataa ctttgaaggg gcctatatag
    26341 ctacaaaata tttattagat actggaaata agaaaataat atacctaagt ggtccacttc
    26401 aaaatgaaat agctatagat agattagaag gatataaaaa ggctctaatc gagtgtaatt
    26461 taagctacaa tactgattat gtatttgaag gaaaatataa gattgaatgg ggacaagaat
    26521 ttataaaaaa tttagaaaag atagattttg atgcaatatt ttgtgcaaat gatttgattg
    26581 caataggtgt cataagaggt cttaaagaaa gaggattaag tataccaaat gatgtgagtg
    26641 ttgtgggatt tgatgatatt caaacatcaa gtctaataag tccttctctt accacagtaa
    26701 gacaaccatc ttatgatata ggatataaag ccagtgaaat attgataaat tgtttaaagg
    26761 gagataaaaa agaatcgttt gatgaattga ttttcaaacc agaactagtc ataagagatt
    26821 cgacaaaaga aagtgaataa cagcatgaaa gacataaata gatatgtaaa ggagtaatgt
    26881 aatgggaaac atagttgtaa taggaagtgt aaacatggac atggtatgtt ctgtagataa
    26941 aagaccagaa aaaggagaaa cagtattagg taatagtttt tttacatcac ctgggggaaa
    27001 aggtgctaat caagctatct cagcttctaa actaggagca aatgtaaaaa tgatatcatg
    27061 tgtaggggaa gatagcctag gagaggagtt aataagaaat tttagaacca ataaagttga
    27121 ttatagctta gtatccagaa ataagcataa aagctctggt gttgctgtta taacattatg
    27181 tgaaaatgat aatagtattg ttgttgtacc agggacgaat gagttagtag atatagaatt
    27241 aattaagaag aatgaagaag agataaagaa tgcagatata gtattgttac aattagagat
    27301 tccattaaaa acaataaatt atgtagtaaa tttctgtttt gaaaatagaa ttaatgtttt
    27361 attaaatcca gcaccagcaa taaaattaga tgaagatata atagagaaag taacttattt
    27421 aacaccgaat gaacatgaat ataagatagt ttttgacaca aatgaagaga tagaagaagt
    27481 attaaaaaaa tatccaaata aacttgtaat aacagaagga aaaaatggag ctagatttta
    27541 tgatggaaat gaagttaaac atgtatcttg tataagtgtt gatgtccaag ataccacagg
    27601 agcaggagat acatttaatg gagctttggc agtagccata acagaaggta aaaatctata
    27661 tacagcagta gaatatgcag tagtagtatc aggtctttct gtaacgaaat taggtgcaca
    27721 atctggtatg ccttataaag aagaggttga aaaatattta aataacaata aataaaaatc
    27781 taatttgttc aaatttaaaa ctattaaaag tggaggttaa ttatgaaagt gagaaaaatt
    27841 ttatctttag gaattgctgg aatactagca ataggaatgt taacagggtg ttcaatggaa
    27901 ggaccaagta aatcagacaa taaaggtgct tcagacaaga aagatttaac tattggagta
    27961 tctacaataa ctcttcaaca tcaatttttt atagatattg atgagggaat aaaagaaaaa
    28021 gctaaagaat taggtgtaaa agttatagta aatgacccag accaagatgt agctaagcaa
    28081 acatcagcaa tagaagattt tatacaacaa aatgtagatg gaatgatagt acttggaaca
    28141 gataactcgg ctatagtacc ggcagtagaa ggagcatttg aaaaaatgcc tgtagttaca
    28201 gttgatgctg tattaaatac tgaaaatatt acaagttatg taggaacagt tagttatgat
    28261 gctggtaaaa aattagggga atacactaaa aaatacatag atgaaaaatt aggtggaaag
    28321 tcagaaatag caatagtaac agatttaaaa tctcaaatac aaatgcagag aatagatgga
    28381 tttaaagatg cattaaaagg ttcagcaaat gttaagatat taaattcaca accaggatat
    28441 gacagagaag aatctcttaa tacagtagaa aacttaattc aatctaatcc agatgtagat
    28501 ataatatatg caacagctga aaatagtgta ctaggagcta aagctgcact tgaatctgca
    28561 aaaaataagg atgttaagat tgtaggattt gacttaactg aagaagcatc aagtggaata
    28621 acagatggaa ctattcttgc tatgattcag caacagccta aagagatggg acgtttagct
    28681 gtagaagcag tagtaaaagc tataaaaggg gaaaaggtag aaaaaaatat accagtccca
    28741 gctttacttt atgataagga aaatataaaa gactttaaga attagcaaaa aaaatgagat
    28801 tatttgaaag aaatcctatt taaaaaggag tgtcattatg agtaatataa ttctgaagtt
    28861 aagcaatatt gctaaagaat ttcctggtgt caaagcatta gataatgtta attttgagtt
    28921 atttcatggc gaagttcatg cactactggg tgaaaatggt gctggtaaat caacaatgat
    28981 aaagatttta actggtgcac attcgaaaac ttctggaaaa ttcatttttc aagataaaga
    29041 aatagagaat atatccccag atgtctctaa aaagataggt ataaacgcca tatatcaaga
    29101 attaacagtc tttgatgaat taacagtagc acaaaatatt tttatgggaa aggaaataaa
    29161 tggcaaagta ttaaccaatg acaaaaaaat gaatgaagag gctaaaaaga ttttcgataa
    29221 tatgggaata gatgtaaatc caaatagtct agtcaaagag cttagtatag ctcaaaaaca
    29281 aatggtagaa atagcaagag ttttatcatc agaaactaaa gtattaataa tggatgaacc
    29341 tacttcttca ataagcaaaa aagagactga aatacttttt agacttataa aggacctaaa
    29401 agatagtgga gttagtataa tatatatctc tcataggatg gaagaacttt ttgagatttg
    29461 tgacagaata actataatgc gagatgggaa aacggtttcg actttgaata ccaaagatgt
    29521 atcatctgag gaagaattag ttaatttgat gatagataga aagttagacc aattttttcc
    29581 gaagagaaaa gtagaaataa aagaagaaat tatgagagtg gaaaacttaa ctaagaacaa
    29641 tgtttttaat gatgttagtt ttaatataag aaaaggcgag atattgggaa taggtggact
    29701 agttggaagt aagagaagtg agatagtaga agctatattt ggacttagaa catatgattc
    29761 tgggaaaata tatttaaaca atgaagaagt aaagtttaaa actccatcag atgcaataga
    29821 aaatggacta ggattgataa cagaagatag aaaaggtact ggattgtttt tacaaatgag
    29881 tgtcaaagaa aacacaacta tggctgggtt aaaaaagata tctaagttta aatcaattat
    29941 agatagaaaa aaggaaaaag agattttaga aaaatacata gaagctttaa ggataaaaac
    30001 accacatatg aatcaggtta tacaaagttt aagtggtgga aaccaacaaa aagctataat
    30061 agcaaggtgg cttttattac aaccagatat attaattatg gatgaaccaa ccagaggtat
    30121 agatgtaaat gctaaggcag agatatacaa tctaatggga aatttagtag agagtggagt
    30181 aagtataata atgatatctt ctgaaatacc agaattaata tcaatgagtg acagaataat
    30241 ggttatgaga gaaggtcata taagtggatt tttagaaggt gaagaaatgg ttgaaaataa
    30301 tgtattaaaa ttggctttcg gaggtaaaat taatgagttc aataactaag cataaagaag
    30361 aaaaatcttc tccattattg acaaaattaa caagtgcatt tagagaccaa ggaagtgcag
    30421 ctgtaggact tgtaataatt tttataataa tgagtatagc ttcatctaac tttttaactt
    30481 tagataattt aattaatgtt ggaagacaaa tatcaataaa tgcaatactt gcagttggta
    30541 tgacatttgt aataatcaca ggaggaatag atttaagtgt aggagcagta attgctttag
    30601 taggtacatt ttgggctaca acagtagtga attataatgc acctatatgg ttaggtatga
    30661 tacttgcatt agcaataggg acaatactag gagtcataaa gggtgcaatt atttcaacac
    30721 aaaaactacc accattcatt gtaactttag ccatgttaac gataataagt ggggcaagtt
    30781 ttgtatttac aggaggaaga cctatatcag taaatacaga tgcatttaag atgctaggta
    30841 gaggatatgt tggaccaata ccaataccag ttataattat gattatagtt gtaatagcag
    30901 gacattttct gttaaaaaga actaattttg gacgtcatgt acatgcagta ggtggaaatg
    30961 aagaggctgc tagattatgt ggagtgaaag taaataaagt tatagtaaaa gtatacgcac
    31021 tagctggact actaacagca ttagctggga taatactatc atcacgtttg gcatcaggtt
    31081 caccaactgt tggagatgga gcagaattgg atgctatagc agccgttgtg cttggtggta
    31141 ctaatatgat gggtggttct ggttctatag taggtacatg tataggtgtt gggataatag
    31201 gaatattagg aaatggatta aacttattaa gtgtatcttc atataatcaa atgattataa
    31261 aaggtttggt aatgttattt gctatatgga taaataatat aaaattaaaa aaattagcta
    31321 aatctaaata gcaattaaat tttagtttat aaactataaa aattattaag tttttgtata
    31381 tatttttata ctttaatttg catatatctt tatacattaa atgggaatat gctaagtgaa
    31441 aaagtttact atggcttaaa tagatgagat tagacttgaa attttaaatg taaaaataaa
    31501 tcttaggagg aaatatgaaa aaaattctct tagatacatt aaatagtaaa aaacaagaat
    31561 atatagatta tttaaaagaa cttgtaagta taaagactga agatgttggt catggaatac
    31621 taggtggatt tgaaaaagaa ggacaggaat atattgaaaa acttgcaaat tacataggtt
    31681 ttagtgtaga tagacaagaa atgagcgaag aattaattaa aaaagcaaaa aatatatata
    31741 aagaaggaaa tctaggtcac aattatcaag atagatataa tttgatttgt aagtatagtg
    31801 atgatttacc tggaaagaca attgtattta atggtcatgt agacactatg ccaccaggtg
    31861 atataagtaa gtggaaatat aatccatatc gtgctacaga agataatgga aaactttatg
    31921 gtcttggaat tgctgatatg aaatctggac ttatagcatc aatattagct gtaaagctta
    31981 taaaagatag tggtctaaat gtgcctggta atgtaaaaat aatgtcagta gtagatgaag
    32041 aaggtggagg aaatggtacc ataaatgcag ttatgaatgg tattgatgga gattgttgca
    32101 taatttgtga accatcagaa cataacttaa tagttgcaca tatgggattt gtattctttg
    32161 aagttgaagt taaaggtgtg tctcttcact gtggcagtaa gtgggagggt ataaatgcaa
    32221 ttgagaaggc tatgttgttg cttcaagata taaaagagtt ggagcataac tggcttatga
    32281 tatataagca tccactatta ccttcaccta caataaattt aggtgtaata aatggtggaa
    32341 cagcaggctc tactgtgcca gataagtgtg tatttaactt atgtgtacat ttcttgccaa
    32401 atataatgag ttatgaacaa gttgtaaatg atgtaacaaa tgtcataatg acaagagcta
    32461 atggagattt gtggcttaaa gataataaac caaatataaa catatatcaa tcagggttag
    32521 gctttgagat ggacaaggat tctgattttg tagtgaatgt acataaaata ctagaagaaa
    32581 ctctagggag aagcttagaa ataaaaggtt cgacagctgg caatgatgcg agactaatga
    32641 aaaatttagc tgaaatacca acacttatat taggaccagg ttcaatagaa caatgtcact
    32701 caattgatga atatgttgaa attaaggagt atttagatag tatacttatg tatgcaagtc
    32761 taatattaaa cttataaaag taggaggaat atataaatga aaaaagtatt aatagtaggg
    32821 gaatcttggg taaaaaatat aactcatata aaaggatttg atacatttgt tacaactcat
    32881 tatgaagaag ctgtaaagtg gttgaaagaa gcaatagaat ctggtggata tgagacagtt
    32941 catatgcctg cacatgtagc agcagatagt tttccttata aattagaaga gttaaatgag
    33001 tatgactgta taatattatc tgatataggt tctaatacgt tcttattatc taatagtact
    33061 tttatagatt acaatagcaa tccagataga cttgaactaa tcaaagagta tgtaaataat
    33121 ggtggggcat taatcatggt aggtggatat atgtcattta caggaataga tgcaaaagct
    33181 agatttggag aaactgctat caaagatgta ttaccaataa caatgataga taaagatgat
    33241 agagttgaaa aaccagcagg aataattcca gaagttgttg actctgaaca tccagtatta
    33301 aaaggtatac caacagaatg gccgaagttt ttaggatata acaaaacagt tgctagagat
    33361 aattgtcctg tgttagcaac tattggagga gacccatttg tagctgttgg tgagtttggg
    33421 aaagggaaat ctgctatctt tagttctgat tgtgcacctc attggggtcc aaaagaattt
    33481 actgattgga aatactataa taaattatgg gttaatatgc ttgactggtt aacatgttaa
    33541 aaattttata aaacttgaaa acctcttact tgataaaatg aaatttacaa gttaagaggt
    33601 tttattgcat aaaatggctg taaagtagaa aatattttta aatcgttaaa attagttatt
    33661 ttggctaatg aatggataag ttattagaaa taaggaggtt tatacaatta atatgagtga
    33721 tttaaataaa aaatttttaa tagaatatat agatgagata caggaagagt tgagagatat
    33781 atcagataaa atatggaaaa atccagaact tcagtataaa gaatattatg cttcaaactt
    33841 acaaaaagag tatctaaaaa aacatgattt tagtatagat gaattagagg gtatggatac
    33901 agcatttgtg gctagttatg gagaaggtga accagttata gcagttttgg gagaatatga
    33961 tgcgttagat ggtttgtctc aaaaagtatc cattactaaa gaacctattt tagatagtgg
    34021 tgcgggtcat ggatgtggac ataatttact tggtacaggt tcaatagggg ctgtaattgc
    34081 agtaaaggaa ttaatcaaac taaaaaaatt gaaaggaact ataaaatact atggatgtcc
    34141 agcagaagag gatttgtcag gaaaagtact gatgataaaa aaaggttttt ttgatggaat
    34201 tgattgtgct tttagttggc atccatttga tataaatact ccaataagaa tcccaacact
    34261 tgctaactat tctgtgaaat ttagatacaa tgggattagt gcccatgcag cacaagctcc
    34321 ttataatgga agaagtgcac ttgatgcagt ggaacttatg aacataggtt gtaattattt
    34381 gagagagcat atatttgata gctgtagagt acattatgta actactaatg gtgggaaaat
    34441 gccaaatata gttccagatt ttgcagaagt atggtattac ataagaggaa ttaaaatgga
    34501 gcatgtaaga gatgtatttg acagaattgt tgatatagca aaaggagcat cattaatgac
    34561 tggtactagt atggaatatg acattataag tggagtatat gattatattc ccaatacaat
    34621 attaaccgat atcctatcac aaaatatgaa attgatagga gtgcaaaact ataatgaaga
    34681 tgattaccat tttgcagaaa aattagctga aacggtgtct atagataaaa gaattagtgt
    34741 ttctagtgtg ttaagtggaa ataaggatat tactaagatg aatttacatg gtgaagttac
    34801 agatgatact tttactcata ataactgtat atcattatca ttggatattg gagatgttag
    34861 ttacataatt cctacagcac aatgttcttg ttcggtttgg cctattggta tttctgctca
    34921 tacatggcag tcttgtgcca gtgcaggttc tgatatggga tttaaagcta tgttgttagc
    34981 atctaaatct atagcatgtt caataaatga tgtgatgctt gatgaggtga ttataaataa
    35041 agcaaaaaaa gaattgaaga atactatagg tagttttgaa tatataccaa ttatttaaaa
    35101 cttaaattga taatataagc atgaacaact tatataagta tataatttaa tattattttt
    35161 aacttaacct tctaattatt ttaaatttaa gatacaatga ttagaaggaa ttttttaagt
    35221 tttttagaat actgtatctt atataatctt gataaaaagt gttatactat atataatcta
    35281 aataaaaaat agtacaaaaa ggagtattta tgtttggata tgttaaaata aacaaaatgg
    35341 atttaacatt tagagaatat gactattaca aggcttacta ttgtggacta tgtaaatact
    35401 taaaaagaaa tcatggagaa atctctaggt tttctttgaa ttatgatata acatttttaa
    35461 ttgttttatt aacagcagta tataacccag agtctataag cacagaagaa gtatgtatag
    35521 taaatccatt taagaagaaa aaggtaatta caaatgatat tacagaatat gcagcaagta
    35581 tgaatattct tttaacgtat tataaattag aagataattt aatggatgat agacgcataa
    35641 aagataaact ggcatattat atatataaaa ataaattaaa attagcatat gaaaagtatc
    35701 ctgaaaaagc agagtatata aaacaacaat taaatgaatt aaataaatta gaaaaagaca
    35761 aaaatataaa tatagatgaa gtatctagta tatttggaaa tataatgggt gaagtatttg
    35821 cctataaaaa agatgaaaat gagagaaact taagaatgat aggttttaat ataggtaagt
    35881 atatatatct attagatgcc tatgaagatt tagatgaaga ttttaagaaa ggaagatata
    35941 atccatttat agagtatatt gataaaaatg atgagttaaa agaaaaagta aaaaaaataa
    36001 tagtgacatc attagggttt ttagctaggg gaattgataa tctaaatcta aataaaaatg
    36061 ttggaataat agaaaatata atttattctg gtgtttattt aagatatatg aatatattag
    36121 aaagcagagg tggaaagaat gtacagtaat acttataata atgaacattt tatgagagca
    36181 agagccttca tagaaaataa tgaatttaaa aaagcatatg attttttaaa aactttgact
    36241 gacaaatgtg cagagtggta ttatttaact ggtttttctg caatgaatat aggatattat
    36301 gaagaaggtg aagacttttt aaaaagagca aaatttatgg aacctgaaaa tagtgaatat
    36361 agtgatgcac ttagaagtta tacacaatat agaaatgatt atagcaatag ggcagacaat
    36421 tataatagaa gaagacgtaa tgatttagat ggatgttgtt gctgttgctg tgatgattgc
    36481 tgttgttgcc taggtgacga ttgttgtgaa aattgtgcta aactttggtg tttagattca
    36541 tgttgtgaat gttttggtgg agatttaata acttgttgtt aggatgataa atatgagtat
    36601 aaaagttgct tatggaggag ttttattagc attaaatgta atattgttga ctcttacaaa
    36661 tattattcct gtaaatacat tgtttattat ggggttagca tcacttttag tatcaattgt
    36721 aataatggaa tggggcttta agagtggaat tgctttttat ataggttcta tagctttagg
    36781 atttatagtg atggcaagta agtctcaatg gattgtatat tcacttacct ttggaatata
    36841 tggtattgta aaatatctta tagaaaaaga taggtctata tatattgagt attttatgaa
    36901 attagtattt gcaaatataa tgatacttat attgtatttt ttattaagaa caatagttta
    36961 tattccaata aacatattta tcataggttc atttgagata gcctttatag tatatgacta
    37021 tgttttcagt tcttttatag gttattacaa taataggtta agaaagatgc tatttaaaaa
    37081 ataatagttg atttttatat ttaattttaa tggaattgta gtttggataa gtgtaaatga
    37141 tatatctgaa tatacattaa aacataaagc taaatttaat atattcttag tgtaactaat
    37201 aaaagctttg atttttagtc aaagctttta tttattaaat ataaatatta cttataatat
    37261 aagtctttaa aatagatagt ataaattaaa tatccactat atttacatct gtagataaag
    37321 aataaataat atcttttctt tctactatta tttcaacatt tttagaaatt tcctcatcaa
    37381 gtgatatttg agacaaaagc tcctttgttg gatttattgc tattggattt ccaactctct
    37441 ttaacatatt tatatctcca ttggtatctc cataggcata cgagtttgat aaatctaagt
    37501 cgtactttac aacaaaatca tttatagcat tattcttact tatagaatcc cacattggaa
    37561 taactgtgcc tgtaaatata ttattttcaa agacataatc acttcctaga aaatcggtta
    37621 cattatattt ttttgccatt ttttcaacaa gaaatccagg gctaccagat ataaatataa
    37681 ctatatgtcc ttgatttaga tgccactcaa tccttgaacg cgtgtattta taaactctat
    37741 ctgcttttaa tttaattact tggtcacttg taaagttgat acaggtttta tctaatcctt
    37801 ttaatgaatc aacataaagg tcacatattt ctaatagata atcatcataa ttaccctgtc
    37861 ttttatccca atccataaaa gtatctctag catgtttata ccaatttttt tggtcaatta
    37921 tatcgtattt aattaatttc ttaaaatgtt caaccataag agagtctcta taaagagtac
    37981 catctatatc aaaaaaagct gctatatttt tcataagacc acctcaatta atcatttcct
    38041 tatattatat tataaattgt atctaagttg ttaaaatata tgtataataa tttatatatt
    38101 aaaaaacaag tattttaaag tttaaaggat gtgactatat gaattttaat tttgcaaagg
    38161 ctacaaattc tagacttatg ggcagtttag gtcttatgat aaattggata gatgatgaaa
    38221 acaatcactt ttgtcaatat tttttattag atgcagaggg attaggatta gcagattatg
    38281 tgagtttaaa aaatccgacg caagaagaag cttatatgga agaagaaagg ttgatgggag
    38341 gatttggctc agatagagtt gaattaacaa aggatgaatc tttattttta gtatcttatt
    38401 ttggtaataa gaatctttat tataataagc tactgccagg agataaatgt gaatatattg
    38461 atattataaa aaactataaa acagatttaa ccatagaaaa attatatgat aaaatatgta
    38521 aaagagttga tgaggaagtt gaatttataa actatatgac tatgagattt atagcatggg
    38581 atagagaaag tttaaagtac ttttctggaa gtgacgagat tgcaaatatg catattacca
    38641 atataaatgg aacattactt aaaaatatag taagtgataa aggtcaaggc agatatataa
    38701 gtgaagcttt atatgaagac aatgatggat attatatatg taaaattgct ttttgtataa
    38761 gtaaatgtta tgaaactggt tttagaatta attctctatt agtaacagat aaagaaccta
    38821 tgtatgattt tgaggtattt gatgaaattt ctaaaagcga atttgtaagt gtatacagtg
    38881 taaattcgcc tgaagagttt gcaggagtat tttatagaga aaatccattt cttttaaaaa
    38941 gtgatatgaa tgaaggtata ttttttacta gatttaattt taataatgac catgtaaaag
    39001 aaaatgtata tgtaataaat aatgatatga aagctatata ttacttaatg ggaaataagt
    39061 tttttattgg tacttatgac gaaaatgatt gtaattatat caatgaaata agtcagtcta
    39121 attatagtga ctatattaaa tttgaagaga attttttctt tgagcaaaat gcattatatg
    39181 attttgcaga atcaggttca ttagattttg atgacttttt ggaataataa atttaggcat
    39241 tatttaagcg agattaactg aatttaatct cgcttaaatt tatttctata atattggggg
    39301 aatattatga ggaatacatt tattattgtg gtcaattatt aaaattttat acagtttatt
    39361 agaaaaaatt tataattttc tttatgttgt ttgctaatat tagtctaaaa tatgagtatc
    39421 ataccattct taactacaaa caaaagaaag agtttattaa atgaaaaagt cagataaaat
    39481 ttaattttat ctgacttttt ctatatttat cttattagat tatgttaata tttgttgacc
    39541 gaataagcgt atattcagtc aactttctat acctataata atattggggg aatattatga
    39601 ggaatacatt tattattatg gtcaattatt aatgttttat acagtttgct taaaaaaata
    39661 tatattacat ttcttcctca tcaaattcct caatattagt agcctgtggt ataccttgca
    39721 tagacatatt actagaacca taaggagtag gatatatatt aggaggcata gtactaggca
    39781 taactacagg cataccttgc attgtattat ggcatataac acctggtatc atcataagta
    39841 cattaggagg catattttga ttacatgaga agttaggaat acccatagta ttattcatat
    39901 tataccccat attactgttc atgttattag gcatacctgt attaccatac atattattat
    39961 tcatattgcc atacatattg ttaggaatac ccatattact attcatatta ttaggcatat
    40021 tgttaggaat acccatatta ctattcatat tattaggcat attgttagga atacccatat
    40081 tactattcat attattaggc atattgttag gaatacccat attactattc atgttattag
    40141 gcatattgtt aggaataccc atattactat tcatgttatt aggcatattg ttaggaatac
    40201 ccatattact attcatgtta ttagacatat tgttaggcgt acccatatta ctattcatgt
    40261 tattaggcat attatttgta gcagatgtat tgtaattcat atttccagat gtattatttg
    40321 tgttaggcaa gttgtttgga gaattactac ttttaggata attatttatg ttattaggat
    40381 ataggttatt tatgttctgg ttattaggta cttttgtata accattagaa atttgagggt
    40441 catttctcaa ttcaccttgg ggaatttctt catttgtaat ataatctgca tagtttgctg
    40501 ggtctaagta aggcatgtaa ctagtatcta aatccttttt tttcttgtta ctcatattaa
    40561 acttgcacct cctagaaaac tataaaaaag tttacaaaaa cttattctaa taatatatat
    40621 attaaaaaag tttataatat gtgcattcta attgtattaa attaataaaa attattgttg
    40681 caaatttaga aatgatagca tataatgaat atatgaacag ttattcatat attaaaataa
    40741 cggaggatta aaaaatgaga gaagagataa atgattgtaa ttgtaatata atacatgaag
    40801 aaatagtaac agaggctaaa tcaactatgc cagatgaaga gatgttatat gatttagcag
    40861 aattatttaa agtatttggg gatactacta gagtaaagat attatatgca ttatttgcaa
    40921 atgaaatgtg tgtatgcgat atagcgagtt tattaaatat gactcactct gcaatatctc
    40981 atcaacttag agtattaaag caggctaggt tagtaaaatt tagaagagaa ggaaaaacag
    41041 tgtattattc attagatgat agtcatataa gtcagatatt tgattgtgga ttaaatcata
    41101 ttagagagac ttataaatga taaatgagag gagtgaatat atatggaagc aaataattta
    41161 attaaaaaag aatttatact aggaggatta aattgtgctc actgtgcaga agagattaat
    41221 gataaagttt ctaaactaca agaggttaaa tcttccaact taaattttat aaataaaaaa
    41281 cttacagtaa atataaagga aagctttaat gaggatgcta ctatagaaaa gataatagat
    41341 ataatagatt caacagagcc aggacttgat atacaaataa attctaaaga aaatgcatct
    41401 aataaaacat caattaaaaa agagcttata ttaggaggat taaactgtgc acattgtgca
    41461 gaggagatta ataacaaagt ttctaaatta aaagaagttg aatcttctaa tttaaacttt
    41521 gtaaataaaa aacttacaat aaatataagc aataactttg aagaggatga tgttataaac
    41581 aaaataaaag aaataataaa ttcaacagag ccaggacttg atatacaagt atggtctaat
    41641 gacaaagtaa aagagagaac tactgaaaaa tcaggagttg caaatgatac aaataagaaa
    41701 gaattaattt cacttataat tggagttctt gtatatatat ttggtatata tcaaacggct
    41761 acaggttatg aaagtcagtt tagtaatata gtatttatag ttgcctatgt gataataggt
    41821 ggtgatgtag ttttaagagc aataagaaat atatcaaaag gaagagtatt tgatgagaac
    41881 tttttgatgg ctctagcaac agtaggagca ttagcaatag gagaattatc agaagcagta
    41941 ggagttatgc ttttctacaa agtaggagag tatttacaag gtgttgcagt tggtaaatct
    42001 agaaaatcta taacttcact tatgcaaata agaccagatt atgcaaatct aaaagttaat
    42061 tctgaagtta aggtggtgtc accagaagaa gtaaaggtag gcgatataat agtagtaaaa
    42121 cctggtgaaa aagtaccatt agatggtgta gtagtggatg gagtttctat gctagatact
    42181 tctgcactta caggagagtc agtgctgaga gaagttgaaa aaggagatga aattttatca
    42241 ggtgttataa ataaaaatgc tttattgagt attgaagtta caaagagttt tggagaatca
    42301 acagtttcta agattcttga ccttgttgaa aattctagca ttaaaaaatc aaagacagaa
    42361 aactttatat ctaagttttc cagatactat actccgatag tagtaatagc tgctttacta
    42421 atagcattta taccaccact tgtaatccca ggtgaggtat ttagtgattg gttatataga
    42481 ggattgatat ttttagtcgt ttcttgccct tgtgcattag ttttatcaat accacttagt
    42541 ttctttagtg gaattgggtt tgcatctaaa aatggtatcc ttattaaagg aagtaactat
    42601 ttagaagctt taagaagtgt agacacagta gtatttgata aaacaggaac acttactaaa
    42661 ggtgtgttca atgtaactaa gttaaatcct gaaggtatat cagaagaaga gttattagaa
    42721 tatgcagcta ttgcggaggt aaattcaaat catccaatag caaagtctat attaagttac
    42781 tataataaaa aaattgattt agatacaata gacagctatg aggaaatagc agcttatgga
    42841 attagagtaa agcataatgg caagtttata ttagcaggta atgagaaact tatgaaaaaa
    42901 gaaaatatat cttattcatc agccaaagaa gtagggacag tagtctatat tgctgttgat
    42961 aaagtatata gaggttatat agttatatct gatgaagtga aagaagatag taaaaatgct
    43021 ataaaaagct taaaagcaat aggagtaaaa gaagttgtaa tgttaactgg agataatgag
    43081 aaagtagcaa aaaatatagc tcgagaatta gaattagata cagtttactc aaatttactt
    43141 cctaatgaaa aggtggatag attagaagag ttatatgaag gaagaactga aagagaaaaa
    43201 atagcatttg taggtgatgg aataaatgat gctccagtat tagctcgtgc tgatgttggt
    43261 atagctatgg gaggtttagg ttcagatgct gctattgaag ctgcagatgt agtgcttatg
    43321 acagatgagc ctagcaagat atctaaagca attgaaatag ctaacaagac taataaaata
    43381 gtgtggcaaa acataatatt tgctttagga gtaaaaatga tagttatgat attaggagct
    43441 ggaggagtag ccactatgtg ggaagctata tttgctgatg taggtgtgtc acttatagca
    43501 gtagtaaatg ctatgagagc tatgagataa ggaataaatg taaatctata ctattcaaaa
    43561 aacttataat tatatattga agtatacaat gatgaaaggt atcaataagt ttcttttaac
    43621 tttattgata cctttttatt ggagtacttt tgtatatata aatctatatt catttataaa
    43681 tttgtattca ttatgtttat ttaatgcatt tatttagtat ataacttttg tattgtaatt
    43741 ttaaaattta gatatagagg atttattgat aaatttatat taagtttaaa ctagactcat
    43801 aaaaattata atacttacga ttgcatatat attatattaa tagttataat ttttacaata
    43861 aaatgtgtgt gctaagatac tctaaatcaa caatataact gccattcaat aaattatgta
    43921 atataataaa gtgaaaaatt taaaaaaata atttaaaaaa gtgttgacg
//
LOCUS       DAMKOJ010000028        42014 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.030, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000028 DAMKOJ010000000
VERSION     DAMKOJ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42014
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.030"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            39..707
                     /locus_tag="PC592_001637"
     CDS             39..707
                     /locus_tag="PC592_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HDF4055614.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSTNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFKVNRYALRDNLAI
                     CFIYFSFIFLLNTLTNSQYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(799..2250)
                     /locus_tag="PC592_001638"
     CDS             complement(799..2250)
                     /locus_tag="PC592_001638"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDF4055615.1"
                     /translation="MNIKCSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEVYKSS
                     DVNVLNLNLNSDEIGSFAEGILLGNYKFDRYKTKSKNFERKEVDTITIFTEKDVECQI
                     KKAKILANSTIIARNLVNEPSNVIYPKTLAIETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIINSMANKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKVKGATGEPVRTLYYLAEI"
     gene            complement(2266..2706)
                     /locus_tag="PC592_001639"
     CDS             complement(2266..2706)
                     /locus_tag="PC592_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4055616.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            complement(2944..3372)
                     /gene="ytfJ"
                     /locus_tag="PC592_001640"
     CDS             complement(2944..3372)
                     /gene="ytfJ"
                     /locus_tag="PC592_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HDF4055617.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3326..3955)
                     /locus_tag="PC592_001641"
     CDS             complement(3326..3955)
                     /locus_tag="PC592_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HDF4055618.1"
                     /translation="MEFNELFNFKYLIIAVIFLISVTMLILISHINILIMADINNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSVYRLLKKI
                     KIHELYSNINFGTENIGLTSSVYVLINTLYGNLFNIIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIKSRIKDLFNIIIMINKIMNKNKGNKEGDSNESNRFNTESYGNNS"
     gene            complement(4113..4652)
                     /gene="scpB"
                     /locus_tag="PC592_001642"
     CDS             complement(4113..4652)
                     /gene="scpB"
                     /locus_tag="PC592_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDF4055619.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIVNKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVVTNE"
     gene            complement(4654..5373)
                     /locus_tag="PC592_001643"
     CDS             complement(4654..5373)
                     /locus_tag="PC592_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDF4055620.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            complement(5403..5999)
                     /locus_tag="PC592_001644"
     CDS             complement(5403..5999)
                     /locus_tag="PC592_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HDF4055621.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYMY
                     KFESMSYIILLIALFTGIYRIILTPIYAVLLKIVYLFV"
     gene            6297..7133
                     /locus_tag="PC592_001645"
     CDS             6297..7133
                     /locus_tag="PC592_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4055622.1"
                     /translation="MKKEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPEFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLH
                     SNLENTNIEVQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPINAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            7154..7576
                     /locus_tag="PC592_001646"
     CDS             7154..7576
                     /locus_tag="PC592_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HDF4055623.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFEDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(7786..8949)
                     /locus_tag="PC592_001647"
     CDS             complement(7786..8949)
                     /locus_tag="PC592_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF4055624.1"
                     /translation="MKKLASTALAILLAFTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGDIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELVNTKDINKASYLQMLQRIIDNMI"
     gene            complement(9003..9203)
                     /locus_tag="PC592_001648"
     CDS             complement(9003..9203)
                     /locus_tag="PC592_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HDF4055625.1"
                     /translation="MDNVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(9409..11085)
                     /locus_tag="PC592_001649"
     CDS             complement(9409..11085)
                     /locus_tag="PC592_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDF4055626.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGIGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDIYKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            11302..12039
                     /locus_tag="PC592_001650"
     CDS             11302..12039
                     /locus_tag="PC592_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF4055627.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTLGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKI"
     gene            complement(12156..12614)
                     /locus_tag="PC592_001651"
     CDS             complement(12156..12614)
                     /locus_tag="PC592_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF4055628.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(12896..13183)
                     /locus_tag="PC592_001652"
     CDS             complement(12896..13183)
                     /locus_tag="PC592_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDF4055629.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(13261..13686)
                     /gene="ruvX"
                     /locus_tag="PC592_001653"
     CDS             complement(13261..13686)
                     /gene="ruvX"
                     /locus_tag="PC592_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDF4055630.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKEETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(13838..16009)
                     /locus_tag="PC592_001654"
     CDS             complement(13838..16009)
                     /locus_tag="PC592_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055631.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGKKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYGTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILSTFGLE
                     NKEMVGRSYTLVNKEDNVNYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKGNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLYVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAILLAVSAVVVVFAFAALDIVSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(16019..16276)
                     /locus_tag="PC592_001655"
     CDS             complement(16019..16276)
                     /locus_tag="PC592_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDF4055632.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(16301..18940)
                     /gene="alaS"
                     /locus_tag="PC592_001656"
     CDS             complement(16301..18940)
                     /gene="alaS"
                     /locus_tag="PC592_001656"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDF4055633.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVKLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAKEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGSISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(19008..19246)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19389..20468)
                     /gene="mnmA"
                     /locus_tag="PC592_001657"
     CDS             complement(19389..20468)
                     /gene="mnmA"
                     /locus_tag="PC592_001657"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDF4055634.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDDVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNEN
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGKDTIKIVFDEAQRA
                     ITKGQSVVMYDEDIVVGGGIIEKSL"
     gene            complement(20752..21192)
                     /gene="nifU"
                     /locus_tag="PC592_001658"
     CDS             complement(20752..21192)
                     /gene="nifU"
                     /locus_tag="PC592_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HDF4055635.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAKKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(21246..22439)
                     /gene="nifS"
                     /locus_tag="PC592_001659"
     CDS             complement(21246..22439)
                     /gene="nifS"
                     /locus_tag="PC592_001659"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HDF4055636.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(22457..22903)
                     /locus_tag="PC592_001660"
     CDS             complement(22457..22903)
                     /locus_tag="PC592_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF4055637.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(23012..23782)
                     /locus_tag="PC592_001661"
     CDS             complement(23012..23782)
                     /locus_tag="PC592_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4055638.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADIDELGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRARGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(23813..25078)
                     /locus_tag="PC592_001662"
     CDS             complement(23813..25078)
                     /locus_tag="PC592_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDF4055639.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKNFYKINATNSSLEDIKNVISELGSINNISGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKIDIEKGL
                     KRAVEVLNKDSYMDIECNKDAIEYIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDIIKASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSVYYIPQENKTEKNIKKYLEYLDGDF"
     gene            complement(25194..25979)
                     /gene="codY"
                     /locus_tag="PC592_001663"
     CDS             complement(25194..25979)
                     /gene="codY"
                     /locus_tag="PC592_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDF4055640.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDAQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(26144..28231)
                     /gene="topA"
                     /locus_tag="PC592_001664"
     CDS             complement(26144..28231)
                     /gene="topA"
                     /locus_tag="PC592_001664"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDF4055641.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELANEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDAKKVQDAHEAIRPTSVDRTPDSIKASLSKDQYKLYNLIWRRFVASQMEDSIF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(28264..29364)
                     /gene="dprA"
                     /locus_tag="PC592_001665"
     CDS             complement(28264..29364)
                     /gene="dprA"
                     /locus_tag="PC592_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDF4055642.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICQYDKEYPENLKNIYNAPKLLF
                     YKGDIDLVNNKFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(29383..30984)
                     /locus_tag="PC592_001666"
     CDS             complement(29383..30984)
                     /locus_tag="PC592_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDF4055643.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDISNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQKIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLNDKSKKENEELEKDNSYIDFKYTKINDEESKYNEDF
                     EDIKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISIEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLIAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFR"
     gene            complement(31015..31359)
                     /locus_tag="PC592_001667"
     CDS             complement(31015..31359)
                     /locus_tag="PC592_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDF4055644.1"
                     /translation="MNNKEKGDFGEEIAVNYLLSKGARILEKNYRLKIGEIDIIAKMG
                     REVIFVEVKSRSNIKFGYPCESVSYKKRKKIIGIANYYIIKNNLNNTPVRFDVIEVYL
                     LEKRINHIVNAF"
     gene            31543..32706
                     /locus_tag="PC592_001668"
     CDS             31543..32706
                     /locus_tag="PC592_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4055645.1"
                     /translation="MNRKKLVAFIRYLSLFILVVSYLKNVENTLYPVIIMMILFIIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFTLVIISSLIISLDKNIYLALESSSVLLIITILSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLISELVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIGLYRLIQESLSNSSRHGKATEIKIFMTFNPSNFIITISD
                     NGIGCGNIKKGNGLNSISERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            32699..33346
                     /locus_tag="PC592_001669"
     CDS             32699..33346
                     /locus_tag="PC592_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055646.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKTNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTPEKMIEQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISKELFLSEGTIKNNITNILGKLELRDRTQLAIFAFKNKIVIE"
     gene            33475..34410
                     /locus_tag="PC592_001670"
     CDS             33475..34410
                     /locus_tag="PC592_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055647.1"
                     /translation="MDIVRVNNITKRFNDKLALDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGNLLKERINEALEVTGLTEVKKKKVKKLSDGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDMSKKYETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NAYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISILENNSLLELDIDKKLQLTEI
                     LSVIDKNNSKIIRISYEEPNLEDVFLNLTGKNLRD"
     gene            34424..35524
                     /locus_tag="PC592_001671"
     CDS             34424..35524
                     /locus_tag="PC592_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055648.1"
                     /translation="MKLYMSVKTMLKGLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNHLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIIGNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRIIGITFKGNFAILLLLCALSSYFMTSISTFVNS
                     FFSKKYGTIIVYALLFLQTIFGGIFSMISDAFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLITSTILIALAIVKEKYKWREVQ"
     gene            35524..36588
                     /locus_tag="PC592_001672"
     CDS             35524..36588
                     /locus_tag="PC592_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055649.1"
                     /translation="MIRLTVANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDNLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKMDKNIDDKLTKTNIIDN
                     KLDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFTLLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWIARVFKNESSIS
                     LISTFYSLIGLAISLSSLIPSMDKLSFMANLSKLTPFYWTIDAIKNNGSILINIIILI
                     LIGTIFVTAGSLKLRDFAKN"
     gene            36832..37329
                     /locus_tag="PC592_001673"
     CDS             36832..37329
                     /locus_tag="PC592_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF4055650.1"
                     /translation="MYKIGESVMYPKEGACCVNDIVTKKINHQMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDKFIQSIDKTDGVWVFDRKQRLKLYHDKFHSGDVF
                     EIVKLIKMLMIQDCSKQLCSTDKEFLNKAQRFALSELAAAQCKSYTVVLEEMKKHILN
                     SKSKN"
     gene            complement(37502..37750)
                     /locus_tag="PC592_001674"
     CDS             complement(37502..37750)
                     /locus_tag="PC592_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055651.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(37817..38833)
                     /locus_tag="PC592_001675"
     CDS             complement(37817..38833)
                     /locus_tag="PC592_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF4055652.1"
                     /translation="MEYNELLKNARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVEQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(38891..39658)
                     /locus_tag="PC592_001676"
     CDS             complement(38891..39658)
                     /locus_tag="PC592_001676"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDF4055653.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYNKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDIAQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(39726..41915)
                     /locus_tag="PC592_001677"
     CDS             complement(39726..41915)
                     /locus_tag="PC592_001677"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HDF4055654.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRDLAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEEFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNLMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKENKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        13446 a         7229 c         4473 g        16866 t
ORIGIN      
        1 tagatacata ttaaatttat tataggagag aatgttatat gtttaaaatt tttctttttt
       61 ctagtgaaca atttgtaagt ctctttatat ttggattatt tttatactat tgtccaaaat
      121 taaccaaaaa tattttacct tatagctata cagtcgagaa gataatttgt acattgcttg
      181 taataattat ggctctagag caattattac ttatttcttc aggtaattat agtaccctaa
      241 attctttacc aattggaatc aattatattt gcatatatct gtgtatagct atactgattt
      301 ttaagcagta tcatcttttt aatatatttt tttcttggag tttagtttgt tcagttggag
      361 aacttatttt ttctacaaac ttgggttatg aatttcctag cttaatatat tttatattta
      421 tcttctctaa gtgcttaata atttatgcag atatatatat ggttgatgtt agaaaattta
      481 aagttaacag atatgcactt agagataact tagctatatg ttttatttat ttttcattca
      541 tatttttact aaacacactt accaattcac aatactatta tggtttttta agccatagta
      601 caactgctat ttttacattt atttttgtta ctagtattat gtacatacct gctcttttat
      661 ttaatagaga tacttttata cttgaaaaaa agaaaaagag taaataattt acttaaataa
      721 aaaataaagc cacatagata accttaaatt acaaaaatat ccacgtggct ttataaatta
      781 tattctataa ttgttgtttt agatttctgc caaatagtac aatgttctca caggttctcc
      841 tgtagccccc tttactttgt atccaattga ttttgatgat gtacttgtcc ctgctatatc
      901 catatgtatc caaggagtat tcccaacaaa ttcaccaata aaagctcctg cagttataca
      961 tccagcattt ttaccaccag tgtttttaag gtctgcttct tctcctttta tcatatcttt
     1021 aaattcatca taaattggca tcttccatac tctttctcct gataaagtgg cggctttttc
     1081 taattcacaa taaaaatcat cattatttgt tactatagga gttgcaacat tgcctaacaa
     1141 tgttaaggca gcaccagtta atgtggctac atcaaccacc tttgtcactt tttcattgtt
     1201 tataatgtag tatattgcat cagctaatgt aagtctacct tcagcatctg tatttaaaac
     1261 ttcaatagtt ttatttgcca tagaattaat tatatctcca ggtttgtatg aacctcctga
     1321 taaagcattc tcacatgcag ccactactgc tataacattt ttctttaatt tactttgaga
     1381 tatagcacac atagcaccta taacactcgc ggcaccagcc atatcggttt tcatatctag
     1441 catagaagca tttgatttta aagaatatcc accagtatca taagtcaatc ctttacctac
     1501 tagacctaat atatccgtac tttctttgtc tccaaagtat ctcattacta tgaatcttgg
     1561 tttattaatt gaacctcttg aaacagcgaa aaaagcatcc attcccaatg cctttatttt
     1621 ttcttcttca taaacatcaa cattaaatcc aaactctgca ccaagtttga ctgtttctat
     1681 tgctaatgtt tttgggtata ttacgtttga tggttcatta actagatttc tagctattat
     1741 agttgaatta gctaatattt tagccttttt tatttgacac tcaacgtctt tttcagtaaa
     1801 tatagttata gtgtcaactt cttttctttc aaaattctta ctttttgtct tatacctatc
     1861 aaacttataa tttccaagta atatcccttc tgcaaaagaa cctatttcat cactatttaa
     1921 attaagattc agtacattaa catcactact cttatatact tcatttttca atatattttt
     1981 taatttttta cacaaattcc cacctatgat tctaattttt tctctattca ataactctct
     2041 cttaccaaaa ccaacaagac aaacatttac caaattgtta ttttcaacca atgttacagt
     2101 atctatacta ttttctttag aattaaaatt tctgcttatc atatttattt tatcaaatgt
     2161 cgtagaaaca tcttctccct caaatagagc tactactgtt atagcatttt ctaaactttt
     2221 taatatttct ttagaacact ttatattcat aataaattct cctttttaaa atagttgttc
     2281 tattatattt ttagattctt ccaaagaagt aaataattta tctttattat ctatatctaa
     2341 gcaatccatt ttatcactta ttatagacac aaactttagt atttcattat ccaatatctt
     2401 ttctccattt ttagttattc cataaaaagt atttcgtcta tctctactat cttcttctct
     2461 atatacatac tcttgctcaa ccaatttatt aagtagtata cacaaactag aagtagatac
     2521 atgtaaatct ctacttaggt ttttaagctc tattttatca tgttttctta tttttactaa
     2581 ggcaaagaac tgtctttctg taagaacctt atctttttta tatctttcgt tattaataat
     2641 ctttattaaa ttatgaaaat tattcatact ttctaacaac aaaatagata attctttatc
     2701 gctcataaca ttcacctcaa aactaatgat ttataactcc ctcttatatc tcaaatgtgt
     2761 ttatatatct ataatataat acttcttttc tttttataat tatactatat atcaacttta
     2821 ttatctattt aaattgtttt aaactaaaat cttattagat ataaatgttt aaagtacaca
     2881 gcaaaatagt gggatttata ctaaccccac tactttattt aaaaccatat acatatttta
     2941 ttcttacata ttgtttttat cttgattctt attactttgt gatatatttt gaattttctc
     3001 caatactcta ggagttatag ataatatatt atccactaga ttgatattgc tatctaaact
     3061 cattattcta gtttctccac tttcaactac tacaaacgct actggttgta cagatatagc
     3121 ccctgcacta cctccagcaa aattcgtatc tgatttttca ttttttaatt caatttccct
     3181 atctttatca tcatatcctt ttgaatattc tcctcctcct ataccaaaac caattgtaac
     3241 ctttgatata ggtacaacca ctgtagtatc tgtttttata gggtctccta taatagtatt
     3301 tgcatctata gaacctttaa ttgtttcaag agttgtttcc ataagactct gtattgaacc
     3361 tgttgctctc attactatca ccttccttat ttcctttatt cttattcata attttattaa
     3421 tcattattat aatattaaat aaatctttta ttcttgattt tatatgtatc cttatatttc
     3481 ccaaaacata atcttttgta aaatctggat ttacatttaa atacattttt tctgcatcaa
     3541 ttatattaaa taaatttcca tacaaagtat ttatcaatac atatacagaa gatgttaagc
     3601 caatattttc agttccaaaa ttaatatttg aataaagttc atgtattttt atctttttta
     3661 ataatctata aacgctcaaa aggtcatcag ctaataatat acttgaatct atattattct
     3721 tcatcccctc ttttttatca ttatttttac tattttcagc tggataaagt tgtctattta
     3781 tatttattaa attaaacatg tattttatat taagctttaa gcaaatatct ttgttgttta
     3841 tatcagccat tattaagatg tttatatgag atattaaaat caacatagtt acacttataa
     3901 gaaaaattac agctattatt aaatacttaa aattaaataa ttcgttaaac tccatattta
     3961 tattatcatc aaaaaattac tatttatact taattatcca tatttatttt aagagaatta
     4021 tcattttata tttatacaaa aaacacaaca acttagagaa ttttaaatct ttcaaagtta
     4081 aaaattctct aagttgttgt gtttttatat ttttattcat ttgttaccac ttcttgataa
     4141 ttttctatag gaggcaactc ttcaagactt tctatattca acaactttaa aaattcatct
     4201 gttgttttat aaattattgg tttccctatc ttattcagtc taccagcttc tcttataagt
     4261 tcattttcaa acaaagtttg taatacctta tcacatttta ctcctcttat atcctctatt
     4321 tctacctttg ttattggttg tttgtaggca attatagtta gagtttctaa tgtagcttgg
     4381 ctcaaacttt tctttttctt tggttcaata atcttcttta tatattctgc atagtctttg
     4441 tttgtacaca tttggtactt attctctaac ttgattattt gaatacctct attttgttct
     4501 ctgtactcct caataagtaa atttaacata atctctattt cttttgatga aagttcttta
     4561 tttactatat agtttaattc ttttatactt atcggctctc catatgcaaa cataacagat
     4621 tctataatat actttatatc ttctcttttc attttaacac tccgaacttt ttcttattag
     4681 aatatcatca aaaaatatat cttgtactac aactatttct ttttctttta taagctctaa
     4741 tatagataaa aaagtagcta ttatttcatc attttcatat gattttataa tatttgtaaa
     4801 agtaacttca atcttatctt ttataatatc tcttatatac aatatctttt cttctacaga
     4861 tattatcttc ttccttacta ttttgtctag tttctcatca ttagcatttt ctatctgtga
     4921 tgttttaact ttaaatatgt atgggagtat attttttatt gcttctattg atatatcttc
     4981 taaatctaca ttgtcatcaa taattatctc ttctttattt ctataaaatc tctcattaac
     5041 ataagttata ttttctttta tatcttgtga tgctacctta aactttctat attcttctag
     5101 cttttccata agttctattc ttgggtcttc ttcttcatct ttttgcttat aaagtagata
     5161 tttagacttt atttctaaaa gttttgatgc catagttata aactcactag ttatctctaa
     5221 atccatttta tctagcattt tcaaataatt tagatactgc ttagttatat ctattataga
     5281 tatatccttt atgtctattt tatgctttgt tattaaatca tacagtaaat ctaatggccc
     5341 ttcatagacc tgtaattgta tattatactt catatcaatc cctctttaat ctgtttatta
     5401 tattaaacaa ataaatatac tatttttagt agtacagcat atattggagt taatattatt
     5461 ctatatatac cagtaaataa agcaattaat aaaattatat aactcatact ttcaaatttg
     5521 tacatatatt cattccattt atacggtaca aatgtagata taactcccca tccatcaagt
     5581 ggtggtattg gaagcaaatt aaaagctgca aatccaatac tatataaaaa cacatattca
     5641 gctattgtat ttatcgcata catatgcaca tatttattga taattacaca aagtatggca
     5701 gtcaaaacat tacaaaaaac tcctgcaagt gaaactatca ggtttcctat cttataattt
     5761 ttaaagttat ttggatttac tggtactggt tttgcccatc ctattttaag aataaacata
     5821 gccaaaagac ctattgggtc aacatgtctt acaggattta atgtcattct accataagct
     5881 ttagctgtat catctcccaa taagtgagct gaataagcat gaccaaactc atgtattgat
     5941 atcgccatag ctataccaac taaacttgct actatttctc ctatattcat acttaacatt
     6001 aatttacatc tcctaaatca aattttttaa tattattata acaattaaat aacttataat
     6061 caaaattatt ttatattata ataattttaa cttctaggca taaaattaaa atttgctttt
     6121 tattttataa cttttattat tatatcatat tcgttgtgaa aatataataa ttacactact
     6181 gtaagtgtaa tattatattg acatgaattg acattattat gttttagtca atatcataca
     6241 agaagtataa aaaaatatgt gttacacttt ttataacatg aaaggaggtt aactaagtga
     6301 aaaaagaaga acgcacagta tgctttgata gggaattaaa aattgaagca tatagattta
     6361 aaggcataat gcaaaaattc ccaaaccatt ttcatgaaca ttatgtaatt ggttttatag
     6421 aaaaaggtca aagatattta tcttgtaaaa ataaagagta taccacaagt actggagatt
     6481 tgctactttt taaccctttt gatagtcata cttgtgaaca aatagatgat aaagtacttg
     6541 attacagatg tatcaatatt aagccagaaa taatgaaaaa aactgtcttt gaaattacag
     6601 ggaaaaatta tttaccagaa tttaatcaac ctgttatatt tcgcagtgag ctagtacctc
     6661 tactacaaga attacactat ataatcatgg aggaagaatt ggactttaaa aaggaagagc
     6721 tttttttctt tctaattgaa caattaatcg aagaacatac agagccaaat ttgcattcta
     6781 acttggaaaa tacaaatata gaagttcaag cagtatgtga ttatttagaa aataattatg
     6841 ctgaacatat agtacttgat gaattaagca ctatagcagg tatgaataag tactctctac
     6901 ttcgtaattt tacaaaatta aaaggtatta caccatatag atacctagaa aatatacgag
     6961 taaacaaagc taaaaagctt ttagaaaaag gtgtagagcc tataaatgct gcgatacaaa
     7021 caggatttgt agaccaaagt cactttacaa acttttttaa gaattttatt ggtcttacac
     7081 caaagcagta tcaaaatata tttataaatg acgattcaaa taactttaaa taaggtaaaa
     7141 aggagaaata aaaatggaaa ctaaaaattc aaaatgtgtc atggtaatag atgaaaattt
     7201 accaatggga attatatcta atacagcagc tataatggga attacattag gaaaacatgc
     7261 tccagaaact gttggaccag atgtaattga caaaacaggt aatagtcact taggaattat
     7321 tgacattcct gtacctattt taaaaggaaa caaagaaata ataaaagatt tacgtaaaaa
     7381 attatatact ttggaatttg aagatttaac tgttgtagat ttttcagatg tagcacaaag
     7441 ttgtaatctt tatgaagaat ttacacaaaa gattgctagt gttccagaag atgagttaca
     7501 gtattttggt atagcaattt atggaaataa aaagaaagta aataaactta ctggtagtat
     7561 gcctttactt cgataagtgt taatcattca tgtatatgat attaaatcaa atgatattgt
     7621 atgatacata aacttttcta tatttatata aagtcataag attataaaat acttatatac
     7681 agtaaataaa aataccccta tggaaaataa ttacataagg gtatttttta tgtgtattat
     7741 aattacatct ttgtatatta taattatatt tcacttgata attatttata tcatgttatc
     7801 aattattctt tgaagcattt gtagatagct tgccttattt atatccttag tatttaccaa
     7861 ttccacttcg cctattactt ttttatcttt acatatcttt atctttccta aaacagttcc
     7921 ctttttaatt ggcatcttag gattttttac tatttcaatt ttcttctcaa attctttaga
     7981 gcttcctttt ttaataagag catttaaatc ttctttagca accaatttaa ctttgttttc
     8041 atcagcctta tccaatgtaa gtgttgctat attatcgcct ttactacata acttaacact
     8101 ttcataatta gcaaatccat agtttaaaag actagatgca tcattaaatc tttctggaga
     8161 tgtctctgct cctaaagttg cagcaactag atgagtatta cctctctttg cagatgctga
     8221 taaacagtat tttgcttctt gagtaaaacc agttttaaca ccagtagctc cttggtagtg
     8281 ttttataagt ttattggtat ttgcaagacc tactgtaact tgtttcttcc ctactacaac
     8341 cttatccatc catgtagtta agtatttact tatcatttca tgttttaaca attctctaga
     8401 cattagtgct atatcatgag cagatgtata gtgattagca actggaagtc catttgtatt
     8461 tgcaaaatga gtatcattca tatttaactc ttttgcctta gcattcattc tatcaacaaa
     8521 cccttcaaca cttccagcta agtgttcagc catagcaaca caagcatcat ttgctgaagc
     8581 aacagctata ccctttaata acgtatcaac cttttgagtt tctcctggtt ctagaaatat
     8641 ctgactacca cccatactag acgcagtttc acttacttga acttcatcat caagcttaat
     8701 atcacctgaa tctaaagctt ctacaataag taacattgtc attacctttg taacactggc
     8761 aggaggaagc tttttatgtg catccttttc atataaaatt tgtccactac caacatccat
     8821 caaaattgct gattttgaag atatatttag ttgattggca tcagcatttt ccttattatt
     8881 tgcaaaagaa aaactcaaag gagtaaatgc aagtaatata gccaaagcag tactagctaa
     8941 ttttttcatc gatgtcacct cttaaagttt atttaaactt attttctcac atttaacttt
     9001 ttttattcta aatgcctaga tataccttga cctaaatttt ttttcttttc aagcttttta
     9061 aagtaacctt ctaaaacacc tttattagat gcattttcta ttatttcaaa agcatcttca
     9121 taattcattc catactctcc tgctatttcc atttttgttt gttttaaagc ttttatagca
     9181 ttttgtcttg aaacattatc cataagaatc ctcctatcag taaaatttat atataagtag
     9241 tttttactaa taaaagattg ttataattgg tattttatgt aatatacata ttttctaaat
     9301 caaaaactaa aaagacctct tgtaattctt aagataatat caattggatt tttgatatta
     9361 ctttaaaaat tacaagaggt ctaattttca aatttatagt tttttatatt atacttccat
     9421 tattatagga agtatcattg gatttcgttt agttttttga tataaatatt cttttaggtt
     9481 ttctttaata ttattcttta aataagccca ttctttaata tttttctctt cacattcatt
     9541 tagaacattc ttaattatat ccttcgcacc atccatcaaa tcttctgact ctcttacata
     9601 tacaaatcct ctagaaatta tatctggacc tgctaaaact ttaccctcat ccttagaaat
     9661 agtaactaca actatcataa gaccatcttc tgataaatgc tttctatctc ttaaaactat
     9721 attacctaca tcgcctactc ctagaccatc aactaatata tttcctgttt gtatacggtt
     9781 tgctacctta gcagaatttt tatctaattc taaaacatct cctgtttgca tgacaaaaat
     9841 attttctttg tccataccaa gctgttcagc tatttcagca tgtcttttta acattctata
     9901 ttcaccatga gctggcataa aaaactttgg tctaactaat gcatgtataa gttttaattc
     9961 ttcttgacag gcatgtccag aaacgtgtat atcagctata tcactgtata ctacttctgc
    10021 tcctttttca aataagaaat tgattactct tgatattaat ttttcatttc ctggtattgg
    10081 atgagcagat attataacta aatcgccact ctttatttct acttttttgt gctctgaaaa
    10141 agccattcta gcaagagctg acataggttc cccttgtgaa ccagttgtta ttatcactaa
    10201 ttcactatct tcatacttat atatatcatt taaatctata agcatgtcat cagaaatatc
    10261 tagatatcct aattcttttg caactccaac tacattgacc attgagcgac ctgatatagc
    10321 aacttttcta ttaaacttct cagcagtatt tattatttgt tgtaatctgt gtatgttgga
    10381 tgcaaaagta gcaactataa ttcttctgcc atttcctttt gcaaataatt cgtcaagacc
    10441 tatcccaaca gtcttttcag acatagtaaa tcctggtttt tctgcattag tactatcagc
    10501 cagcattaaa agaactcctt ttttgctcaa ctcacagatt ctatgcatat ccataacatc
    10561 tccatcaata ggagtcaagt caatcttaaa atctcctgta tggtatatta taccttggtc
    10621 tgtgtgtatt gcaatagagt aagcatctgg tatactatgg ttatttttca aaaactctac
    10681 ttccatatta tcaagcttta taacttgtct aggacctata acatttaact taacattatt
    10741 catcttatgt tctttaagtt ttacttgtat aagacctata ctaagtcttg ctccatacac
    10801 aggtacattt attttcttta atatatatgg aagagctcct atatggtctt catgtccatg
    10861 tgtaataaat atacccttta ttttatccct attttttact aaataagtta tatctggtat
    10921 aactatatct actcctaaca tttcatcctc tggaaaacta agtccagcat ctataacaat
    10981 tatttcatct ttatactcaa caacagtcat atttttccca acttcgttaa gtccacccaa
    11041 ggccattacc tttatcttgt tggtgttctt tttgaacaat tgcatcatct ccttctgtct
    11101 atttaatttt ttaacacgtt ctacaatcat aaataatatc aaatcacgca ctcgctacca
    11161 gttattctta ttgtaccata attcgtatca tattttaagc tatatttaaa atacatttaa
    11221 cgtattattt tgacaaacct attttatttt gatatcctct aaatattata tgatttaata
    11281 tcggataatt taggaggatt tatgcgtggt aaaactcatt gtgcaatagg aatcttaaca
    11341 gctatccaga catctttaat atttaaaatt cctatatctt tagttgatat tttagtttca
    11401 gctacttttg ctgtactgcc cgatttggat aaatctaatt ctatggtctc aaatttcatt
    11461 ctaaagaaca atgtatccaa atacatatat agaattttta tatatgctgt taatattatt
    11521 attttcttta tttcaataaa tataaatgat aatttttatt taagcgcaat aattacattt
    11581 gttgcaatta taattattga agcaaaacta acccacacat ttctaagaaa agtttttcta
    11641 tcattaatat ttatactatt agctatatgc ttatacatca tagaagttga aatatatttt
    11701 acaatttttt gtctaatgtt gtcaattttt ccatggttaa agcacagaag tttttctcat
    11761 agcatatttg caactataat agtatatttt ttactaaaac agatagaatt aatcactaat
    11821 attaataatt tatcttttta tggtacgctt ggttatgcaa gtcatatgtt tttaggagat
    11881 ttatttacaa agcaaggaat accaattttt tatccactaa gcgaaaagaa aatttcttta
    11941 ggatttttaa ctgttggagg accatttagt aatttcatag aaaaatcatt catttttgta
    12001 cttataggat taattatatt ttcaatatta aaaatataat tagtttaaaa actatatatt
    12061 tacactttat agattgctta taataaaaaa tggaagaata gcatagaata taaaagttct
    12121 atactattct tccattgaca ttaagcaata gaagtttatt cttctgagtc gcttactcca
    12181 ttacactcgt cacataatcc ataaaattta acatcatgat caagtatttt aaatttgtac
    12241 aatgattgta tctctttttc tatattgtct aaaaggtctt ctttagcttc cattatcttt
    12301 ccacaatttt tacaaataag atgatgatga ttatgacagt cttctttatg tagactaatc
    12361 tcatatctta tacatccatc gtctaagttt agttttgata ttaaccctat ttcatccaat
    12421 agttgcattg ttctatatac agtagctaat cctatttcag gacagtcaac cctaactaaa
    12481 tcatagattt cctcactact tagatgtgaa tggtcatgtt taagcaatat ttcaactatt
    12541 gctcttcttt gtggcgtaat cttaaaacca gtttctttta acttgtcttt taataaatcc
    12601 attgtatttg ccataacatc acccttacta ttttcaattg ataatcttta ttaaataata
    12661 ttgtaattga taattcattt tttgtcaaga catttaaata aatttaattt attctcataa
    12721 tataaatatg tacccataaa agatatatta ttcaccaaaa ttcataaatt tcttgatatt
    12781 tttaataaaa aacaaaaaaa cagatatata ctataagtgc ttttacaatt aataaggttt
    12841 aattaaagca aatataataa atacctgatt tttatataca aacttaatta tttatctagt
    12901 taagtccatt tgattcatct tcgtcgtagt ttaaaccctc ttcttccatt atagcagtat
    12961 atacagctac aacagtttca tactcttcat cactttctaa aggtattaag atttcacctt
    13021 cttcatcctc atcaattcta aagattaaag cttcttcagc ttcttcatca tctaaaggca
    13081 ttaatattgc atactctttt ccttctgctt ctaatgttaa tattatttca aattggcttt
    13141 caacgccatt ttcgtctatt aaatttatta tattttcttc cataatgtca ttcacctcaa
    13201 atttattttt atttttatta tctatattat atatcataag tattcaattt tatagttctt
    13261 ttatgaattt attttaaaat ctaaatatcc ttgcaaaatt attactgctg ccaacatatc
    13321 tataaccttt tttctttttt gtctactgac atctgcctct aataaagacc tctctgctgc
    13381 tactgtggaa agtctttcat cccaaaattc tacatcaata ccagtttctt cttttaccaa
    13441 ctcacaaaac ttgattactt tttctccttg tgggcctaaa gttccattca tattttttgg
    13501 caatcctgat acaattttat ttacctgctt ttcttttatt attgctttta gctcttcaat
    13561 atcttttttc ttaccaaccc tttttattgt ttttacacct tgtgcagtta gtcccatcaa
    13621 atcactcaca gcaactccaa tagttttatc accaacatca agacccatta ttcttccatc
    13681 tagcataatt cctcctttat ctatttatat tccatagatt aaatacatat tatcaatcat
    13741 aaaaattgca atatgatttt ctatgtaagc atacagttta cagtaataat catattgcat
    13801 tttttattta aattctatat gaacagtaaa aaatttttta gttatttttt tcaaatatta
    13861 tcatatttat acttattatt attagtggta taagtatata tatagatgct gtagatgcag
    13921 caactattcc ggaatcatta actaaaagag tgattataca accaaccata gatgcaataa
    13981 accctttaaa caagattgga aaattattca ttatctttct aaagtgtcta gatggtttaa
    14041 atataagtac tgcaattact ccaattccta caagtaaaat atttacccat acacttgtct
    14101 gtgctagttg catattcatt tgaatttttc ttccaaatgt ttgtaatatc tctcctggtc
    14161 catttaggaa aattctttgt acaaacatac ctaaatgaga ttcactacct gaaactatat
    14221 ctaaagctgc aaatgcaaaa acaacaacta cagctgaaac agctaataat atagctttct
    14281 taaaatctat tttaatgtca tatataagca ttataaacaa caaatatgct acacattctg
    14341 atatagctcc accaacattt gcacccattg aaggatatgc actagttata agtattatta
    14401 acgaaaaaat tacaacatac aatttagata ccttcttata atgtaataat actgctaagc
    14461 caaatactgc acttgctata gttacaccct catattcatt tcctacacca tagtacctag
    14521 ctcctatgac agcatcataa ctcattatgt tattttgcat caagtatgtt ccaaatacag
    14581 aatctataac tatgactaaa atagtaagtg ttgcaaaaaa tcccatgtgt tttatatcat
    14641 tgcccttaaa caattttcta cctaacaagt ataatattag cgtagtcgca aatattccca
    14701 aagatattga aattggagtt ttaaaattca tcaaaggagc taacataaat gatagtggca
    14761 ttattatgcc taattttata aactccttaa gtactttgaa tacacgctct ttatgtggca
    14821 tataatttct aaagaaaatc gcaaacattg caattaccca agaagcagat attacaccta
    14881 caaagccatt tataatagtt gaccttattg aagatataga cactatcctt tcataaagtg
    14941 attttagata attaacgttg tcttctttat ttactaaagt ataacttcta cctaccatct
    15001 ctttattttc aagaccaaat gtacttagta tatccactcc aacatctaag ttggcaacaa
    15061 ttccagcctt ccttgttgtg gcagattcca gtagaccttt cccttctcca ctaaatttta
    15121 ttattggaga aagtcttctc ttattcttat aatctaggtc acttggaaat gcacttgcta
    15181 tataaacagt gtcattttct ccaaccatag aaaatacttg ttcaagatat ttatttatat
    15241 tttttacaat attcttcttc attgtaccat aagtattatc atttagattt aatctataca
    15301 tatctaatct atatgtatct ccaagttcta caaatatagc atcactattt ttataggatt
    15361 tcttagtttc atctagtaat ttatcgtagt ctgtagatat tccaaatggc attttagaat
    15421 ctttcttatt aatattatca atattacctg aatcaattct tccatattgg tccatagcta
    15481 ctagacataa atttctattc ttaactaatt gattattttc aattatatca gcatttccaa
    15541 ttacagatgt ctttaaacca ttttctgata aagtttttcc taatgaccct aaatttgctc
    15601 catactctcc atactcaaga ttttcattta tagatctatt aatacctaaa tcatttattt
    15661 ctttagcttt tttacctgtt gcgacttcaa aagctttagc agtatcttgg tctacttttt
    15721 gaaaattgat atagtcttca gtagttacac tagctcttgt tcctgcaccc atacttgcat
    15781 aagaccttct atcatcagta ccttgatccc ctcttatatt catgagagct acatatcctc
    15841 tcttttctat ctcatttttc aagattggaa tattcatcat acttccaaga ttggtcctat
    15901 tcatatcaat aaatatgacc ttgccttttt cttcggcaaa accatagcta gcagttgata
    15961 caaaaatcat aatgactatt gcaaacaacg acataatctt ttttctcatt tatttgacct
    16021 actttctatt cagatagtgc gtgattactt cttcaagtat ctcatctctt tcaaattttt
    16081 taattatagc tcttgcattt ttatgactag ttatatagct agaatcacca gaaaggagat
    16141 accctataat ttgatttata gggttatatc ctttttcaac tagtgcttta tatacaaaat
    16201 caatagtatc tcctacactc atcctatctt ctggtattcc ctcaaatttc atagtgtagt
    16261 ctaaatcttt ttccaaacta aaaacctcct tgagtgaatg ttatttaact tgtgtcttaa
    16321 taacctcact tgcatagctt aaagcttggt caaccttaga tacatcacta gctcctgctt
    16381 gtgccatatt aggtcttcct ccaccttttc ctccagctat ttttgcaact tctctaacaa
    16441 tattacctga atgtattccc ttatctaata catctttagt ggcagtaact acaaagttaa
    16501 ctttatcatc tactacattt gcaagtacta ctacaccaga accaagctta tctcttagat
    16561 tatctgctgt ttctcttagt gtatccatat ccataccttc aaatttatta gttatcaaat
    16621 taactccatt tacttccact ttagaatcaa aaatagaatc aactgactgt aaactcatct
    16681 tagctttcat atcatgcaat tctttagata agtttttatt ttcttctaat aaagaactta
    16741 ttctttgaat taaattatct tctttagatt ttaagtttac acaaacttca gagataattc
    16801 catctctttc ttttaggtat tcataaacag cttttcctgt tattgcttct attcttctta
    16861 cacctgctgc tactccacct tcagataata ttttaaacat tcctacttga gaagtatttg
    16921 tcaagtgagt tcctccacaa agttctgtag aataatctcc catagaaact actcttacct
    16981 catcaccata tttttcacca aatagtgctg tagctccttt ttctttagct tcctttatat
    17041 tcataatatc acattttatg tctaaagatg ataaaataac attatttact ttttcttcta
    17101 ttacttttaa ttcttcattt gatattgctt caaagtgagt aatatcaaat ctaagtcttt
    17161 ctggagttac taaagaacct gcttgattaa catgttctcc taacacttct cttaatgctt
    17221 tatgaagtaa atgtgtagca ctgtgatttc ttgcagctga cattctagtt tctctatcta
    17281 ctagagtctt tactttatct ccattactta tgctaccaga ttttattata cctatatgtt
    17341 ttatactatt attagcacct tttttagtat ttaatacttc taaaactaag ttttcattag
    17401 ttatcaatcc acaatctcca acttgtcctc caccttcagg atagaaagta gtgttatcta
    17461 gtactataga taccttatcg ccttcttttg cactttgaac tagctcatca tctttaacta
    17521 tagcttcaat agttccttca ccataaattt cactatatcc attaaatgta ctatcaactg
    17581 tagattctaa ttttgataga gggtcttcct tccaactttc tccatccata tttcctctag
    17641 catttctagc tctttctttt tgcttttcca tttcttcatt aaaagcttct tcatctacag
    17701 atagatgttc ttcttctaat atttctttag ttaggtctat agggaatcca taagtatcat
    17761 atagtttaaa agcttcttga ccacttagga cagtctttcc ttcatttttt aatacttcta
    17821 tataagagtt caatatttct gttccttggt ctatagtttc attgaatttt tcttcttcta
    17881 ttccaactac ttttttaata tagctttctt tttcaactaa aactggatat gctttatcat
    17941 ttacttttat aacttcatct attagtttct gtaaaaataa ttcttttact cctaataact
    18001 taccatgacg agcagcacgt ctaagaagtc ttctaagaac atatcctctt ccttcatttg
    18061 atggaagcac tccatcacta actaagaatg ttacggctct tatatggtca gttattattc
    18121 ttattgatat atcatttttt ggattctctc catattttac tcctgttaac ttctcaactg
    18181 cttctagtat agatttaatt gtatctactt caaagatagt atctactcct tgcattatac
    18241 atcccattct ttcaagaccc atacctgtat ctatattctt attttctaat aaactataat
    18301 ttccttcttc atctctatca aattgagtga atacatggtt ccaaaattct aaatatctat
    18361 cacaatcaca gcctggttta cagtctggat tgtcacatcc atattcttct cctctatcaa
    18421 aatatatttc tgaacaagga ccacaaggac ctgtacctat ctcccagaaa ttatcatctt
    18481 tcccaagttt aaccattctc tcttctggga aattcatttc ttttgcccat atatcataag
    18541 aatcatcatc ttcttcatat acagtcaccc atatcttatc ttctggtata tttaaccatt
    18601 ctgtaacaaa ttcccatccc catttaattg actctctttt aaagtaatct ccaaatgaga
    18661 agttacccat catttcaaag aatgtagcat gtcttgcagt tatacctaca ttttctatat
    18721 ctcctgttct tatacatttt tgagatgtac acattctcac acttggaggt acttctacac
    18781 ctgaaaagta atttttcaaa ggtgccatac ctgagtttat aagtaacaaa ctcttatcat
    18841 tatttggtac taaagaataa ctatttgcta cataatgacc ttttgactca aaaaattcta
    18901 aaaacttact tcttatttca tttaatccca tcttttccat atcatgttcc tcctaataaa
    18961 ttttattttt tcgtttaaat aaaaaacctc gtccctataa ataaatttat aggggcgagg
    19021 acaatcgcgg taccacccta attatcatac aaagtatgat atcttcggaa aaccttagct
    19081 ataacgtaac taccgtcaat ctctacttaa atattcttta taaaagataa attgttcaag
    19141 attgctacta aaaggctgct tcaaatatca tattctaagg gcttccagca tttccctctc
    19201 tctgtaagac atcaaatatt ttactattcc ttatcactgt atttgttttt taattaatat
    19261 actaattata ttactaaatt ttacaaaatt aatcaatact atattttcat atacaataaa
    19321 tttattttat aaactttatt tactcttaat ataccttatt gtttattttt ttaatttttt
    19381 agatgttttt ataaactttt ctcgattata cctccaccta ctacaatatc ttcatcatac
    19441 attactacag attgaccttt agtaatagct ctttgagctt catcaaaaac tattttaatg
    19501 gtatcttttc ctactctatg aatagtagct ggtgatggct ttgctgaata tcttattttg
    19561 gcttggactc ttaatggctc ttctaacgta tctattgata taaagttaac atctttggca
    19621 ataagttcct ttttaaataa attttcatta tctccaagaa ctatggtatt gtttattgga
    19681 tttatgtcta ttacaaacat tggttttcca aaagtaattc caagcccttt tctttgacct
    19741 atagtgtaat ataatatccc cttatgcttt ccaagtatat tgcctttagt atctacaaaa
    19801 aaaccttctt caatacgctt tttagaatgt ttttttacat aatttgcata gtcattatct
    19861 ttgacaaaac aaatttcttg actatcaggc ttattgtgta ctgccatacc catttcttta
    19921 gcaatttctc ttactctatc tttttcatag tcacctattg gcaataaagt atgctctagt
    19981 tgctcttgtg taaggttata aagtgcataa gtttggtctt ttttatctgt aacagatttt
    20041 tttaacaaat atcttcctgt actttcatcc ttttctatct ttgcatagtg acctgtagct
    20101 acataatcac aacctatttg tctagccttc ttataaaaat catcaaattt tatatgttta
    20161 ttacaagcta tacaaggatt aggagttttt ccttccaaat attcatctat aaaataatct
    20221 attacttttt ctttaaagac ttctctaaaa tttaaaacat aaaatggtat acctatctta
    20281 tttgctaccc ttctagcatc ttcaacagca gataaagagc aacaaccacc ttcaatttca
    20341 acatcgtcat catcttgcca caacttcata gtaacaccaa tgacatcata tccttgttgt
    20401 tttaaaagat atgcagctac agagctatca actcctccac tcatacctat cattactttt
    20461 ttattcataa acaaatttca cctcatcttt tgcattactt attattatat catatagaac
    20521 aaacattgta tttatttaaa atatagcttg ctctatttta taaaaaaaat aattattttc
    20581 attatctaaa tattatagaa atatattttg ttaattaatt gacttctaaa acaagtaaaa
    20641 actattaatt taagcaataa aaaatagcta ttttacaaac agctattttt tatatctcat
    20701 taatacttct ttttagtcat tttaaacttc tcataacaca attacttatt tttattcttc
    20761 ttcttcaaca tcatggtcat gagcatcatc tataacatac ccatccaatt ctggtatatg
    20821 gatattgttc tttttagcat agtctataag agctgctttt acagcttgtt ctgctaaaac
    20881 tgaacaatgc atctttactg gtggtaaacc atccaaagct tctgcaacag ctttgtttgt
    20941 aagttctaat gcatctttta tagtttttcc ttttatcatt tcagttgcca tagaagaact
    21001 tgctatagct gaaccacagc caaatgtttt aaacttaaca tcctttatta catctccatc
    21061 tatgtctaaa aatatcttca ttatatctcc acatgtaggg tttccaactt cacctacacc
    21121 acttgcatta tcaatttctc ccatatttct tggattcata aaatgttcca taactttatc
    21181 actatattgc attatctttt cctcctactc aatttatgtc tattttttat gctttatctt
    21241 tctgtctatt ttactaaacc ttgtttctta gcatcatcat aaagtggtga catgcttcta
    21301 agtctttcta ttacttttgg taagttctct agtatataat ctatatcatc atctgttgta
    21361 aaatctccaa ctgtaagtct taatgaacca tgtgctattt catgtggtaa acctattgca
    21421 agaagtacat gtgaagggtc taatgaacca gaagtacatg cagaaccact tgaaccagca
    21481 attcctaaca tatctaataa taaaagtatt ccttcacctt ctataaattg gaatgcaaag
    21541 tttgcatttc ctggcaatct attttctaag ctaccattta ctcttgtata aggtattctt
    21601 tctaacacac catctattaa cttatttcta agacgagtta aagtttctac atgattttgc
    21661 atattttcct tagctaattc tgctgctttt ccatatccaa ctattgcagg tatattttct
    21721 gtaccagctc ttttgctttt ttcttgtgct ccaccatgga caaagttatg aagtcttaca
    21781 ccttttctta tgtataaagc tcctacacct tttggtccat atattttatg tgaagacata
    21841 ctcattaaat ctattcctaa ttctttaaca tctactggaa tattacctgt agcttgtact
    21901 gcatcagtgt ggaataatat cttatgtttt ttagctattt cggatatttc tttaataggc
    21961 tgtatagttc ctatttcatt atttgcaaac attatgctta taagtatcgt agtatctttt
    22021 attgaatctt ctagttgttt caagtctact tttccttcgc tatcaacatc taaataagtt
    22081 atttcaaatc catgatgttt tgctaagtat tcacatgtat gaagtattgc atggtgctct
    22141 atttttgaag ttattatatg attacctttg tttttattag cataagctac accctctagt
    22201 gtccagttat cactttctga accacctgct gtaaaatata tttcactagg ttcagcattt
    22261 ataagggctg ctacttgttc tcttgcttta tccaaagcat cttttgcttc tcttccgaat
    22321 gtgtgaaaac tagatgcatt accaaaataa tctgttaggt atggcatcat tgcatccaat
    22381 acttcttttt taataggtgt tgttgcagaa taatccatat acaatcttct tttttccatt
    22441 acattcatct ccaaatctat tttttaatat ttgttatatc attttctaat ttatttttgt
    22501 tatagtcatt tatcatatct ttaagagtaa ttgaatctat aacatcttct ataccctttt
    22561 tcatcttttc ccaaactatt tttgttacac acatgtttga gttttcacat acatcttcat
    22621 ctagtacaca gtcagataat gcaactggcc cttctaatac tacaagtata tctcctactg
    22681 ttatgtcttc agcattcttt gaaagcaaat aacctccttg agcgcctctt acacttttta
    22741 ctagacccga tttttttaaa gatgaaaata tctgttctaa gtactgatct gatatttttt
    22801 gcttcttagc aataaatttt aatgacactg gtccattgtc ttgatttaat gctaattcaa
    22861 acattgcttt tagtccatac ctacctttag tagacaactt catatattat cacctctata
    22921 tagaaatcta attcatactg ttttagtagg aattactttc aagataattt tattataccc
    22981 tactaatttt gtcaagatta attttaattt tttattttga ataaattccc cattttccaa
    23041 tgttttcaaa tcctagtttt ttatatatct ttccagcctc ttcattatca taaaacaggc
    23101 aaggaatttt gttttctctc aataactctg aacatagttt aattaggcac tttgtggcaa
    23161 gccctctagc tctatattta ggatgtgtcc ctactccaat tatcattgca tgagtcctat
    23221 tttctgaagt actctttgcc attgacacta cttgtttgtt aatctctata caatatcctc
    23281 tacctgtcct tagtccattt tttaaattct ctaaagttgt actgtgaaac tcatctatta
    23341 aatcataaag tttcactgtc ttttttagat ttccaagcct aattctctta acctttgcat
    23401 tacaattatt atctatcaaa aactttttag tttgaagttt gcaaaaatca actaccttta
    23461 aattattaag tcctaatctc tttgctaaag catctacagc acatatttta ccagatattt
    23521 cttcataatt agtattacga agtagattgt aaaaaccttc aacatcatac tctccatcag
    23581 aataaaacat cataaattca aaatatttaa gtaatattgc ctttatttca ccaagttcat
    23641 ctatatctgc ccatatattc aaaaaattat ttccatatcc atatctttca atatccccta
    23701 ttataaacaa attgtactca ggttcttttt ttaagtattt cataactcta ctgtgataag
    23761 ttgagttaag ttttataatc ataatatcta cccccgatac ataaagttca gtctaaaaat
    23821 ctccatctag atactctaaa tattttttta tatttttctc agttttattc tcttgtggta
    23881 tgtaatagac actatctttt atgctatctg gtaaatattg ttgttttaca taatgatttt
    23941 taaaattatg aggatatttg tatccacaac ccctacctat ttctttagaa ccagaataat
    24001 gagcatcttt tatactattt ggtatatcct taacaaactc tttatccagt tcatccatag
    24061 ctttcattat tgctatacat gcagaattag attttggaga tgtagccaaa agaatagtag
    24121 cttctgctaa tggtattttc gcttctggaa atccaagttg catagctgag tctacacatg
    24181 cctttacaat tacaatagcg tttggataag ctaaacctat atcttcacta gctattacta
    24241 aaagccttct acaaatactt atcaaatctc caccttttat aagtcttgct agatagtgta
    24301 tagatgcctg tgggtcactt cctcttatgg atttttgaaa tgcacttaaa atgtcataat
    24361 gactatcacc atttttgtca tagtttataa tcttattaaa tgtagatgcc tttattatat
    24421 ctgaatctat ataagttata ttatctttat ttggtttagt tgaataaacc accacttcta
    24481 aaatatttaa agctcttctc atatctccat cagaaagaat ggctatatac tcaatagcat
    24541 ccttattaca ctcaatatcc atataactat ctttatttaa tacttcaaca gctcttttca
    24601 gccctttttc tatatcaatt ttttctaaag gtttaaattc aaatacagta gacctgctta
    24661 aaagagcttt gtatacataa tgatatggat tttctgttgt gctagcaatc aaggttatac
    24721 tcccattttc cataaattct aatattgatt gttgctgttt tttattaaaa ctttgtattt
    24781 catctatata taacaagact ccacttatat tatttatact tccaagttct gatatcacat
    24841 tttttatatc ttctaaagat gaattggtag catttatttt atagaaattt ttattacttc
    24901 tttctgctat tatttccgct actgtagtct tcccaacgcc aggaggacca aaaaatatca
    24961 tatttggtaa aaaattagat tgtaatatct tagacaatat ttttccatta cctattatat
    25021 gactttgacc tattacatca ttcattgttt ttggtcttat tttatctgct aaaggcattt
    25081 tctcactcct ttttaataaa aatacttact ttgtccttac ctcaataatt cgtctaaaaa
    25141 aggtatctat ttgaaataga taccttttct aatctaaacc tataaaatat agattattga
    25201 ttgtttttta atttttttaa ttcatctgtg agtttgtcat taagtattct tatatgagta
    25261 cctttcatac ctaatgatct tgattctatc acacctgcac tctcaaattt tctaagtgca
    25321 tttactatta cagacctagt tataccaact ctatcagcta tcttacttgc tacaagtaaa
    25381 ccttctttgc catccaattc agcaaaaata tgttcgactg cttcaagctc ggagtaggac
    25441 agagtgccta ttgccatttg aactacagct ttctttctca tttcttcttc taattcttca
    25501 cctattgctc ttaatatttc aagaccaaca acagttgcac tgtattcagc tattactaaa
    25561 tcatcatcat taaatgaatt tgaatatctt gaaagtacta atgttcctag tctttgaccg
    25621 cttcctaata ttggaactac tgtagtatat ttttgtaatc ttccatgttc ttcaggaaag
    25681 atttctaata tcttctcacc atttaaattt tctaatgttt catcgatttt taacacattt
    25741 tgagtatatt catctgaaaa tttcttttgc ttagtatact catcttctat aactgaactg
    25801 tcttgagcat catttaaatg aagacctagt actttacctt ttgcacttac tacataaaca
    25861 ttagaactta aaacgtcgcc caatgctccg gccagtaaat caaaagagac actgcttcca
    25921 ccacttgttt gtaatgtttt atttattttc cttgtttttt gtaacacttc acttgccatt
    25981 taatcatctc ctcatgaaat ttaggccttt taataacctt ttatattttc taatattatt
    26041 ttcacattta atgaaaattt atttttctat tagttgttta cacttgaaag attatcatag
    26101 attggaacct ttttcaagag aattatgtga tttttttcaa ttttcactct tttccgtcat
    26161 tatgctcttt tgtttcttta ttacattctt tattagaaca cactgttttt gtttcagatt
    26221 tagtcacttt ttcaaccata tatgaaccac acttctcaca aaactctcct gttggcttgt
    26281 tccaagctac aaagtcacag tttggataat tagaacaccc ataaaaagct ttacctcttt
    26341 tagattttct aagtataata tctccttctt cacattttgg acatttaaca ccaattttat
    26401 tcataattgg tctagttgtt ttacagtcag gatagttttt acaagccata aactttccaa
    26461 atctaccata tttgataacc atattagaac cacagttctc acaaatctcg tcagtttctt
    26521 catccatatt taccttttct atattttcaa gagcttcttc aatagcctct ttaagaggtg
    26581 catatgattc agatacaatc tttttccaat ctgtattacc ttcttctata acatcaagtt
    26641 tactttccat atcagcagta aaatctacat ctataaattt atggaaatta ttttccaaaa
    26701 tatcagtaac tattattcca agttccgttg gacatagact tgttccttgc ttttcaacat
    26761 attctctatt cagtatagta gctattgttg gagcatacgt acttggtcta cctataccta
    26821 gttcttctag cgtttttact aaactagctt ctgtatatct tgctggtggt tgtgtaaaat
    26881 gttggtctgg caatatattt tctatattta atatatctcc tttttctata cttggtaaaa
    26941 ttttgtcttc tctttctgaa aaattatata ccttagtata accatcaaat ttcatttttg
    27001 aaccagttgc tttaaataca atatctccta ttttacattc tacatttagt atatcaaata
    27061 ttgaatcttc catttgacta gctacaaatc ttctccaaat taaattgtat aacttgtact
    27121 ggtctttgct caatgaggcc tttatactat cgggagttct atcaactgaa gttggtctta
    27181 ttgcctcatg ggcatcttga acctttttag catccttttt ttctttttta tcaccagtgt
    27241 ttttatagta gttttctcct agattgttta ctatataacc cttagctttt tcttttgctt
    27301 catcagatat tcttttagag tctgttctta tatatgatat aagaccaaca gtaccttctc
    27361 cttctatgtc gataccttca tataattctt gtgctatcat cattgttttt ttagtagtaa
    27421 aaaataactt attcgctcct tcttgttgaa gcatacttgt tgtaaatggt tttggagctg
    27481 atttacgtct tgatttagat tctatcttct caacctttaa atctttacct tccatttctt
    27541 ttagtatttc attcacagct tcttcatttg ctaattcaat tttttcatca tttttaccat
    27601 aaaattttaa agttatatct ttgtctttta ctgtcttagc ctcaacatct attgtccaat
    27661 attcttttgg aataaatgct tttatttctt tttctctgtc acaaattaac tttgttgtaa
    27721 cagattgcac tctacctgca ctaagacctt ttctaacctt ttgccataat ataggactta
    27781 tttgataacc taaaagtctg tctagtactc ttcttgcctg ttgtgcatca accaaattta
    27841 tatcaatatt tctaggatgt ttaattgctt ttttaattgc atccttagtt atttcattaa
    27901 actctattct acaatcctca gattcatcta aatttaatat atgagctaaa tgccatgata
    27961 tagcttcacc ctctctatca gggtcagttg ctagatacac ttgtttagat tttttagctt
    28021 ctttttttaa ttcctttatt acatcgcctt ttcctcttat atttatatat tgaggttcaa
    28081 aattattttc tatatctaca cctaatttac ttttaggtaa atctctgaca tgaccaactg
    28141 atgctttaac tgtgtaatga cttttcccta aaaatttttc tatagtttta gcttttgcag
    28201 gcgattctac gatgactaat gttttggcca taaaaccata cacccccact acctaatctt
    28261 aatttataca tttaaactgt acgttttatt attcatttct actactaact catttagtac
    28321 taattcattg attattgaat ttacatactt tatttctata ccagtataat cacaaatact
    28381 atctatatgc aagtttcctt ctctttttat agcttcaatt atttgcttag acttggcatt
    28441 tagacttata ttatcatatt tttgatttat ttttttatca ataatattaa atatgttata
    28501 ttcatttaaa atatcatcta tattttcaat taattttgcc ccttctttta taattttatg
    28561 acaacctcta ctcatttgag aatttatatt gccaggtatt gcaaaaacat tttttccatg
    28621 ttcaagagca aaatctactg tgattaatgc accacttttt attgctgctt ctacaacaac
    28681 tactccatca cttaagccac tgataatcct atttcgatta gaaaaatgat atggggctac
    28741 tgtcgagtta atattatact ctgataataa taatccccca ttttctaata ttttatttga
    28801 taaatgtaaa ttttgttttg gaagaggatt gtctactcct gaaccaagta ctgctatagt
    28861 tttagatttt ccactcatac aacctatgtg cgagtatgca tctattccta tagctaatcc
    28921 acttactata ttaactccat attgggatag ttgacaactt attgtttttg cacaattaat
    28981 tccataggct gtaggttttc ttgaacctac tatagctata ttaaatttat tattaactaa
    29041 atctatgtca cctttataga ataataactt tggagcgttg tatatattct ttaaattttc
    29101 aggatattct ttatcatatt gacaaatata tttaatcgct tttttgtaaa gtagttcttt
    29161 tatattttct aaataagcgt gacctctata ttttactata ttttttctaa tattcaagct
    29221 tatatttttt aaattatata tttctttttc agaaaaatca aatatatctt caatatttac
    29281 tatttcattt tctattattt caattgtttt tgttgttatt ccaccaattg attttaacca
    29341 taaataagta tctctttttt ccataaaatc cacctcaaaa cactatctaa aatagctata
    29401 ataagccttt ctaaatgaaa aagcttctat aatacactgt gaatttatca agtctctttc
    29461 ttctaaatct gctattgtcc ttgccatttt taaaagtttt gtataacttc tactgcttag
    29521 gttgtattta ttaaatatca tctcagccgt tttcgaagct tctttttcca gtttacaata
    29581 tttgaataaa ttgtaagctt taatttcact attatttttt atattatctt tcttaaatct
    29641 gtttatctgt atttttctag cattttctac tcttctcttt attttttgag aactttcttc
    29701 ttgttttaaa gaattaaaat ctgaatattt tatagaatta acttctacaa aaatatcaaa
    29761 cctatctaac aatggacctg atattttatt tatgtatcta tcaatttcgt tacttctaca
    29821 tctgcactct gtttctgaca tataataacc acatggacat ggattcatag ctgcaattaa
    29881 taatactcta caaggatatt ttgcactgta ctttactcta gatatattta catatccatc
    29941 ttctataggt tgtctcaaag tctcaagtat ttttctatca aattcagcta tctcatctaa
    30001 aaacaagata cctctatgtg ctaaagcaat ttccccaggt cttgcatcca ttcctcctcc
    30061 aattaaagat tgctttgtag ttgtatgatg aggtgctcta aaaggtcttt tatcaattat
    30121 tcctttagtt tcatttatca tacccaatat actataaacc ttacttactt ctatcatttc
    30181 ttctatactt atatctggta aaattgtcct tactcttttt gcaatcatag tttttcctga
    30241 acctggaggt ccaatcataa acatattatg atttccagct gctgcaattt cagcactcct
    30301 ctttacaaag taatttcctt ttatatcttc aaagtcttca ttatatttac tttcttcatc
    30361 attaatctta gtatatttga agtctatata actattatct ttttctaatt cttcattctc
    30421 tttttttgac ttatcattca aaaaagacat tatccttact ttatcgactt ttatttcttc
    30481 gtttaaaaaa tcgacacatt cttttaaact cttaatagga attatgtcaa tttcatctac
    30541 aaatagactt tcttttatgt tctcaattgg tataaaaata cgctttattt tctgagtttt
    30601 tgcacccata attataggca atatacctct tacttttctt atttttccat ctaatgataa
    30661 ttcgcctata aacatacttt ctcttatgta attttcatct ttttttatta actctcttaa
    30721 aagacctata cttatagata aatctaaaaa agctccttct ttttttatat ctgctggtga
    30781 taaatttaca actattctcg tgcttggaaa tttatatcca ctattaagaa ttgctgactt
    30841 tactctttct cttgcttctt taatttcttt acctggaaga ccaacaatat taaaactagg
    30901 gattccattg cttatatcta cttcaacctt aactaaaaag ctgtcgattc ctactaagtt
    30961 acttgaatta ataatactta acatatttaa tcctttccaa aaacattatc ttttttaaaa
    31021 agcattcact atgtgattta ttcttttttc taataagtat acctctataa catcaaatct
    31081 tacgggagta ttatttaagt tattttttat aatataataa tttgcaattc caattatttt
    31141 ttttcttttt ttgtaactta cagattcaca agggtagcca aactttatgt tagaccttga
    31201 tttcacctcc acaaatataa cttctcttcc catttttgct attatatcta tctcccctat
    31261 ctttaatctg taattttttt ctagtatcct tgctcctttt gatagcaaat aattaactgc
    31321 tatttcttct ccaaaatcac ctttttcttt attattcatg attcactcca atacattaaa
    31381 ttttcacttt taaattatgg tcagtataca attttactat tcaatttttg ggattgattt
    31441 tatttctatc aatattatta aatacttcta ttgactttat tcttttatga tattattcta
    31501 gttttcatag gaaaagttta tttttttgga ggagtgcctt taatgaacag aaaaaaatta
    31561 gttgctttta tacgatattt atctttattt atattagttg taagctattt gaaaaatgtt
    31621 gaaaacacat tgtatccagt cataatcatg atgatattat ttataattat aataaataat
    31681 caagttagat ttttttcttt atcaaatgag aataaattta tacttatttc ttacttttta
    31741 gaacttatat taatttttat actgtgtaat tatacaaaaa cttttaattc gatttacttt
    31801 gttcctttaa tattagatat atcattttta ataaaggaaa aatataagta catattgttc
    31861 actttagtta taatatcttc tcttattatt agtttagata aaaatatata tttggcactg
    31921 gaatcaagtt ctgtattact aattataact atactttcta tatatataga aaatgagaat
    31981 ttatcaaaat tatacagtca aaatctttat gataagctta gaatttccaa ggatgaatta
    32041 aaaaaggtta acgctgattt ggaaacttat gcaagttcta tagaagaatt agcaatttta
    32101 aaagagagaa atagaatatc aagagaaata catgatagtg taggacattc tctttctaca
    32161 acaataatac aattaaatgc tatagaaaag ctcctaaaag acaagcctct aatttctgaa
    32221 ttagtacatg aacttagaga atttgtaact gaaagttttc aagatgtaag aagggctata
    32281 tctgagttaa agcctgttga atatgaaaat taccaaagtt tatttaaaat caaagaacta
    32341 gttaaaagct ttattaagct tacaaatatc aatgttaaat taactatttc aaaaaatact
    32401 tggaacttat ctagaaatca atctataggt ttatatagac ttatacagga atctctttcc
    32461 aactcatcaa ggcatggaaa ggcaactgaa atcaaaattt ttatgacatt caatccttca
    32521 aattttataa ttactattag tgataatggt ataggatgtg gcaatataaa aaaaggaaat
    32581 ggacttaata gtatcagtga aagaatatat gaattaaatg gtaaagttga atttgataat
    32641 tctaataatg gtttcacaat tagagcttct tttcctaaat tttcaggagg tgattttttt
    32701 gaataaaatc aaagttctta tagtagatga tgaaaaatta attaggaaag gtcttaaaat
    32761 tatattatca tcttataatg atttagaaat tgtaggagat gcttctaatg gatatgaagc
    32821 tttagaattt tgtaaaacga atgatgtaga catagttctt atggatatac gtatgaaagt
    32881 atgtgatgga gttctaggta caaggcttat aaaagaatat aataattcta taacattatt
    32941 aattttaaca acttttaatg atgatgaata tataaaagat gctatgaagt ttggagcttc
    33001 aggataccta ttaaaagata gctctgatga agtattgcat gaagggattc gttcttcatt
    33061 ttttggcaat attgtccttg ataaaagtgt agctgaaaaa atcatgaccc ctgaaaaaat
    33121 gattgaacaa gagcatcttt atgacatgta caatttaaca gaaaaagaaa tatccataat
    33181 tagactaatt gcaaatggac ttaataataa agaaataagt aaagaactat tcttgtctga
    33241 aggtacaata aagaataaca taactaatat tttaggtaaa ctagaacttc gtgacagaac
    33301 tcaactagca atctttgctt tcaaaaataa aattgtaata gaataaattt aaaaatataa
    33361 agtgacttaa gtcacttttt ttagtgactt atagtaatag aattataatt cataattctt
    33421 tattatagta ttatagattt ttaacttata caaaattatt ttggaggaat tattatggat
    33481 atagtcagag taaataatat aacaaaaaga tttaatgata aattagcact cgataacatc
    33541 agcttttctg ttaaaaaagg tgagatattt ggacttattg gtccaaatgg tgcaggtaaa
    33601 tctacactta taaatataat tacaaatctt atgttaccaa atagtggtag tattcaaata
    33661 aatggtttag atttatcaaa ggattatata aaagcaaagt ctataatagg attagttcca
    33721 caggaattag caattataga aactctcact ccttttgaca acttagagta ctttggagct
    33781 ttctatggtt taaaaggaaa tttacttaaa gaaagaatca atgaagcatt agaagtcaca
    33841 ggtcttactg aagtcaaaaa gaaaaaagtc aaaaaattat ctgatggtat gcaaaggaga
    33901 ttaaatattg gaatagcact cttaaatcat cctaaaatat taatattgga tgaaccaact
    33961 gtaggtgttg acccccaatc aagaaatcat attttcaatt ttataaaaga tatgtctaaa
    34021 aaatatgaaa ctactgtaat atatacttcc cattatatgg aggaagttga acatctttgt
    34081 tctaaaattt ttattatgga tgaaggtaaa gagattgctt ttggagataa tgcttattta
    34141 aaatcgctag tatctacaaa tacaaaatta attatggaaa taaaaaatat aaatgctcaa
    34201 cttatctttg atttaaaaaa tactaaaggt gttatatcta ttttagaaaa taattcatta
    34261 ttagaattgg atatagataa aaaattacaa cttacagaga tactctctgt cattgacaaa
    34321 aacaactcaa aaataataag aatttcttat gaagaaccta atctagaaga cgtattttta
    34381 aatctaacag gaaaaaattt aagggactaa tggaggtaat tttatgaaat tatacatgag
    34441 tgtaaaaact atgctaaagg gtttaaaaag ctcctttata cttaatttaa tatatttttt
    34501 agctttacct ctgattttat cttggtttct tgggatggtt acagaaagca tgtttcaaaa
    34561 tcctataaaa acagaatcta cacccattgt tatatatgac aaagacaaca caagattatc
    34621 aaatcatttg acaaagtatt tgaaaaatga tttatcttat atattaacag ttaaaaaaga
    34681 tgattctaag gcagaattaa agcttactat acctaaaggc tatgagagta gtttattaaa
    34741 tgaaaaatca aatactctaa atatagaaaa acttggaact cgtgatgata ttgcaatatt
    34801 gcttcaagac atattagata cttaccatga aaaattttat ttaaataatt cccagaaaat
    34861 aagttcagaa gatttctcta aattatttaa taaaaattct attgatactt ctataatagg
    34921 taacaatgtt aaacagagct cttatgaata ctttgcttta gtttcgctag ggtttcttgt
    34981 aataatcttt ataatgaaca atattttatc aaattatata agcgaatcaa aaggactctc
    35041 aaaaagactt tattctatgc ctataactag agtacaattc ttaatttatg actttgtagg
    35101 tttatggatt tattcattta tattcttatt attatatgtt ttattcttta gaataattgg
    35161 aataacattt aaaggtaatt ttgccatatt gctcctactt tgtgctttat catcttattt
    35221 catgacttca atatctactt ttgtaaacag cttttttagt aaaaaatatg gtacaataat
    35281 agtttatgca ttactctttt tacagacaat ttttggaggt atctttagta tgataagtga
    35341 tgcatttact aagcttacaa gtttatctcc tacctattta ataggagaat tgtttagtaa
    35401 ttatgaaaca tttaaaacta tagattcaat aggaaattta attttcacat gtttaattac
    35461 ttctacaata ttgattgcac ttgctattgt aaaggaaaaa tataaatgga gggaggttca
    35521 ataatgatta gattaactgt tgcaaatata aaaagatatc taaaaaatca tactctttta
    35581 attaatatgg ttatgcttcc tattatacta attttttcac ttaatttttt tatcaacaac
    35641 tcgggaaatc aatcaatgta cttttctcca gtagcaattg tatctgactc ttcaggaaag
    35701 tatgaacata agttaataaa tagttctaag ttaaaagaaa attcatttag attaaatgaa
    35761 caagataagg ctatgaatct attaaaaaat aataaggttt ctgctgtatt cgtcttagat
    35821 aaaaattttt caaatagtat agataactta caacgacctg tagttaaatg ctttaaaatt
    35881 gaaaatggtg gtggtagtct ttgggcagaa tcacaaatag aatcttttat tactaaatcg
    35941 ttaaaattga aaatggataa aaatatagat gataaattga caaagacaaa tataattgat
    36001 aacaaactag ataagaataa aggttcattt ttagtagtct tcttgatatg ctattttatg
    36061 tatattaatg cggcacatct tgcttctgat ttatttacat taaaaaaatc aaatgtgcta
    36121 aaaagactta tctctacaga taataaagat ataaaaataa ttttcagtat atttttaggg
    36181 ttatttttta ttcaatcaat tgtatacact tttactctat tatgtttttc aattatagaa
    36241 gactttaatt taagtctgaa tgtattgatg attgtactag caaatagttt tgtttccact
    36301 ggatttgtat tttggatagc tagagtattt aaaaatgaaa gttctataag tcttatatct
    36361 acattttatt ctttaatagg tttggctata tctctatcta gtctaatacc atcaatggat
    36421 aaattatcat ttatggctaa tctttcaaaa cttacaccat tttattggac tatagatgct
    36481 attaaaaaca atggtagtat cttaataaat ataataattc tgatattgat tggaactata
    36541 tttgtaactg caggaagtct taagttacga gattttgcta aaaactagta gttattaaat
    36601 ataattagta tttattttta tataatgata aaagaatatt ccaacatgtt aaatcatttt
    36661 accttatatt tttctattta gttttatata ccatataacc taaacttaat attatatatt
    36721 aacatttttg acttgtcaag ttttttatgg tataatatta attattagat aattaatata
    36781 ctgtacctaa gttgcaatat ctaaaattca gtttggaggt ataactaata tatgtataaa
    36841 attggtgaaa gtgtgatgta tccaaaagag ggagcctgct gtgtaaatga tattgtaaca
    36901 aagaaaataa atcatcagat gcaaaaatac tatgaattaa gtgttatttt caatagtaac
    36961 cttaaaattt cgattccagt tctaaatgca gacaggattg gaatacgtcc agttatggat
    37021 ggaaatgacg ttgataaatt tattcaatct attgataaaa cagatggtgt atgggttttt
    37081 gatagaaaac aaaggcttaa actgtaccat gataaatttc attcaggaga tgtttttgag
    37141 attgtaaaat taattaaaat gcttatgata caagactgtt caaaacaatt gtgtagtaca
    37201 gataaggagt ttttaaataa agctcaaaga tttgctttat cagaattggc tgctgctcaa
    37261 tgtaaatctt atacagtagt attagaagaa atgaaaaaac atatactaaa ttctaaaagt
    37321 aaaaattaaa ccagtcttaa agactggttt tatttttata ctaatcattt atgctactct
    37381 atcttacttt aaactgccta atctaatatt aataaggtta ccctaagtag atagatgtct
    37441 ttattcaaat aaaaaaacta agagtaaatc atattactgg tttactctta gataataaaa
    37501 cttaatcttc ttcaagttct tttttctctt gtaataatac acttaattca tttgcttcta
    37561 aaacttgtgc ctctgcaata tcaagtaact cttgttgcca ttccacacat ttatctttgt
    37621 aatcaaaagg tagcgttctg tcaactatgt acttatcaat acagtcctcc gcacttttaa
    37681 ttatttcttt tctttcatca ataaattttt ctaattctac taaggcttct tcataagctt
    37741 ttctactcat ataaattccc cctttgtaca atttattcta cattaaaacg atttttcctc
    37801 ttttttgtat aaaattttat ttgtatataa cttttccatc aatatctttt atagtttgac
    37861 atccagttaa tatcatagag ctacttagct ctgattgaag tttatttaca taagtttcta
    37921 caccatcagt tgcaccacca aatgaagcag tcacaaaagg tcttcctatt aatactgcat
    37981 ctgcacctaa acctatcatt tttagtacgt ctaaaccagt tctcactcca ccatctgcga
    38041 gtattgtaac tttaccttta acagcatccg caatttttgg taaaacttca catgctcctg
    38101 gtgtacaatc aagtactctt cctccatggt ttgatacaac tattgcatcc acacctgctt
    38161 ctactgccat taaagcatcc tcaacagtca ttataccttt caatataaat ggtagtttag
    38221 tagactttac taactctttt atttgttcaa catttttagg aagtactggt tttccatgta
    38281 gtgataaagt tactagaccg caagcatcta tatcaactcc aactgcaaat gcacccgctt
    38341 cttcagctaa tcttatcttt tttataatat tttcattatc ccaaggttta ataaatacaa
    38401 ttccagctcc attatacttt ttaactacat ctaaattttc cattaaaaaa gcatctactg
    38461 ctgtatcacc aaccattgca taaataccac tattagcaca tcctgcaact actggttcta
    38521 tgtaatctct ttcattaatt tttccaccca tatttaaagt agttcctgtt actggagctg
    38581 caaatatagg tgcactcatt ttctttccaa acatctctat agatgtatca ggatttgata
    38641 catcatgtat tactctcata tttactttta ctttctctaa actcttgcta ttttctataa
    38701 aagaagaacc acttccttta cctcccatgc caggtacttc gcctgcacaa gcaaccccat
    38761 tgcaaacctt acaaacttta caacttccat ttaaattttc tctagcattt tttaataatt
    38821 cattatattc catctttaat cccccattaa ttatagtaat ttatattata tacattatat
    38881 catattatat ttacagtata tttttcaaaa aactttttct gtggatagga gttatgccat
    38941 atttttcaat agcttcatag tgttctttag ttccgtatcc tttgtgagat ttaaatccat
    39001 attctgggta tactctatca tattggtaca ttatactatc cctagtaact ttagcaagta
    39061 tacttgcggc tgctattgat atagattttg aatctccttt tacaattgga ttttgagcta
    39121 tatcaatacc tggtattgtt gctgcatcaa ctaataaata atctggtgct ttttttaaac
    39181 aatttatagc ctttttcatt gccatatatg tagcatttaa tatattaaat tcatctattt
    39241 cttcattgtt tactatacct attccataat ctagtgcttc ctcttttatt acttcaaaaa
    39301 gttcatctct ttttgcctca ctcaatttct tagagtcatt tacaccttct atttttgtat
    39361 cttttttaaa tactacaaca gaagctacaa caggtccagc aagtggcccc cttcccgcct
    39421 catcaattcc tccaatatat aaatagcctt tattatagcc ttcgttctca aatatattta
    39481 tagtttctaa tctctcttct tcttttctaa tattatctag tttttttgct agttttatag
    39541 ctaaaccttg tacagatttt ctttcatcta cccttaatag ttctatatat tccatatatt
    39601 tttctacttc taaagtctct attatttctt taatctccct cacactttta tcctgcatac
    39661 cattccccca tctttcgttt ttaaaaattt aagttttaaa catattaaaa tttcttaatt
    39721 agagtttaat tgcatccact ataaccacat tttaaacata tactacatcc acctgtatgt
    39781 gcaattcctt cacttccaca ctcagggcac acaaattttt catcttcttc aaaattttta
    39841 tttattattt ctttggcttt ttcatcttta ttatcttttt cttttttatt atttttataa
    39901 tattcttttt tactattttc ttttttattt tctttattat tttcttcctt tttttcattt
    39961 attaaaattc cactcctttt acatccatct ctaaatattg ttactccttt aagaccagcc
    40021 tcccatgcct taatatatat attgaaaaca tcttcaactg tagtttcaaa aggtatattt
    40081 attgtagatg atatagaagc atcaatatac ttttgccata ctttttgcat gtttattctt
    40141 tcttcatatc ctatattcat agcagtaaca aaaaaatctg gtaaacattc ttcatctgta
    40201 atacctttct tatccatata ctctttaaca attggagtat atactttata gtacacatct
    40261 tcatcatgta agctttcagt ttttcttata tatgaaagat taaatatagg ttctattcca
    40321 ccactaatac ctatcattgt agatatagaa cctgtaggag gtattgttaa aagttgtgag
    40381 tttctaagcc catacttttt aaccatttcc ttagtgtctt catttaaatt ttctataaaa
    40441 aacttagatt tagaaatatt ttcatattta tactcactaa aagtgccata ttctttagca
    40501 attaatgctg attgctttac agcttcattt aacatagtct taccaattaa atcacataat
    40561 tctaaagatt catcagagcc atatcttatt cccattttta taagcatatc agctataccc
    40621 attacaccta aacctatctg tctatattta tgtacactat ctctttgttc ttgtaatggg
    40681 tgcaagttta atccctcatc taagacatca tttaaagcta ctacagcttc tctaacgcaa
    40741 gattttagtt tattaatatc aaatgtagca tgttcaccaa atggttgtat tataaactct
    40801 gataagttta ttgagccaag tagacaacta cctccacttg gaagtggctc ttctgcacaa
    40861 ggatttactc ctgaaaagca aaagttctta tcttcactca taagattata tgtttttatt
    40921 ttatcccaga ataatatacc tggttctgca taatcccagt tatttttcac aaatttatta
    40981 aataaatcat acgcatttac tatcttaact attttttctc cagtagtttc aacttcaaaa
    41041 gtacaattat ataacttttt ttcccttaca gcttgcataa attcatctgt tactcttaca
    41101 gaaatatttg ctttagtaac cttctccaaa tctgttttta tatctataaa ctcttctatc
    41161 tctggatgat ttacatccat agaaatcata agagctcctc ttctccctct ttgaccaatt
    41221 aagccagttg tcatactata aagttccata aaagagactg ctccagtcgt atgttttgca
    41281 gcattgttaa ctttcgctcc ttttggtctt agctttgaaa tgtcaattcc aactcctcca
    41341 ccataactaa aagttctagc aagttttttt gcagtatcga aaatatcttc tatgctatct
    41401 tttggtggtt ctattacata acaattggaa tatgttactt tttttccttc tttctgtaat
    41461 cctctatttg ctaaaattct tccagcaaat agaaatcttt tttgtcttat tagttttgat
    41521 attcttgaac tattatttga aattctcttt atccattcat caaaactctc accattatgt
    41581 ctatacttgt tcttccatat tgatttttgt aattcatcaa actcccaagc tttagttctt
    41641 atttctgagc gtctttctct atataatatg tagtgttttg ctatatcttt tctatttgat
    41701 tccataagta gtacttcaac tatatcttgt atttcttcta cggataagca tttttccata
    41761 gaattatagt cattggctat ttttcttgat atatcatatg ccaaatctct atctactcca
    41821 ccttcactat ttatactagc tttatagaca gcatcttcaa tcttactttt gctaaaaagt
    41881 tcttttgtac catctctttt tattatgtac ttcattttta gacctccaat aaattagtat
    41941 taaattaata cacacattaa ctataactct aaacaaactt tttatatatt tgtatatttt
    42001 catattaatt atct
//
LOCUS       DAMKOJ010000029        41608 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.031, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000029 DAMKOJ010000000
VERSION     DAMKOJ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41608
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.031"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            184..1377
                     /locus_tag="PC592_001678"
     CDS             184..1377
                     /locus_tag="PC592_001678"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDF4055655.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1582..2700
                     /locus_tag="PC592_001679"
     CDS             1582..2700
                     /locus_tag="PC592_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HDF4055656.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEIYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNVDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVNSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAVGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSALLKYKEAID"
     gene            2831..3076
                     /locus_tag="PC592_001680"
     CDS             2831..3076
                     /locus_tag="PC592_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HDF4055657.1"
                     /translation="MKEKVQIEKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            3063..3809
                     /locus_tag="PC592_001681"
     CDS             3063..3809
                     /locus_tag="PC592_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF4055658.1"
                     /translation="MSQYSDFAFVYDELMNEVDYDGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKDYDIAGIDISDEMLSVAKEKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKQDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENIIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLKE
                     SGFKDIKSYGDFTFDKPKEESQRIFFVCKK"
     gene            4093..4968
                     /gene="hslO"
                     /locus_tag="PC592_001682"
     CDS             4093..4968
                     /gene="hslO"
                     /locus_tag="PC592_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDF4055659.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYTEEELLEILKEM"
     gene            5358..6158
                     /locus_tag="PC592_001683"
     CDS             5358..6158
                     /locus_tag="PC592_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF4055660.1"
                     /translation="MESKTKHIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRKLGVKPQNVIILADIDKKEGTHYELMKKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREHKIKDDLYFIKPKYVKYIPRNERAIYKAMEFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6685..8925
                     /locus_tag="PC592_001684"
     CDS             6685..8925
                     /locus_tag="PC592_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF4055661.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNDIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFSESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYKSLI
                     NGYNIADLTSMQIDELVEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHRGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPNAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNICEGKKFKKEVLEYRFQGKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIG
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIEMGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            9338..10873
                     /locus_tag="PC592_001685"
     CDS             9338..10873
                     /locus_tag="PC592_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF4055662.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTVMTITGSILIALLALIFDFILGLVERFFQRKRKKKNRKKV
                     FAILGSLILIVTIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLKVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTENMFSKLQSEYKNKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNISDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVIVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            10889..11650
                     /locus_tag="PC592_001686"
     CDS             10889..11650
                     /locus_tag="PC592_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055663.1"
                     /translation="MTTIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKRAVDKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNAPANQFVDQLLNIRKSIIDDENLKK"
     gene            11770..12021
                     /locus_tag="PC592_001687"
     CDS             11770..12021
                     /locus_tag="PC592_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDF4055664.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLDTNDVVNWCKTKIE
                     SPNAIINRKGKNWYISIYDCIITVNAHSYTIITAHKEKK"
     gene            complement(12334..12984)
                     /locus_tag="PC592_001688"
     CDS             complement(12334..12984)
                     /locus_tag="PC592_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055665.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSEVKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIAFPLYVDAIPSHLLHFLEECEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWIQGIGIGAGEMFGSLESVPLGKGQKKDLGIALKE
                     LSKNILSNNINIGNSKKNNIFISPNFPRFLYKLIGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(12981..13484)
                     /locus_tag="PC592_001689"
     CDS             complement(12981..13484)
                     /locus_tag="PC592_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4055666.1"
                     /translation="MKLLIHDLTDEELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPTECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKHINLEAIFYGNCITESEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(13533..14048)
                     /locus_tag="PC592_001690"
     CDS             complement(13533..14048)
                     /locus_tag="PC592_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF4055667.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQNHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKIDVEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            14328..14855
                     /locus_tag="PC592_001691"
     CDS             14328..14855
                     /locus_tag="PC592_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4055668.1"
                     /translation="MHEQIDYCERKKIRTIDIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            14839..16242
                     /locus_tag="PC592_001692"
     CDS             14839..16242
                     /locus_tag="PC592_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4055669.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIIVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(16602..16913)
                     /locus_tag="PC592_001693"
     CDS             complement(16602..16913)
                     /locus_tag="PC592_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055670.1"
                     /translation="MKKIIKSFTFWFFLIALFEISMHQIGQDSKSIILIGFNPILSII
                     SRIDSFFIFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(16969..17562)
                     /locus_tag="PC592_001694"
     CDS             complement(16969..17562)
                     /locus_tag="PC592_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4055671.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEIDDNGLLPGSRQHISGANYTVEIMKQAPVTIFIL
                     NILGKSLLENLSPEERFYEMANIQSIGASIQNMSLKAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLNDVTEWR"
     gene            18087..18317
                     /locus_tag="PC592_001695"
     CDS             18087..18317
                     /locus_tag="PC592_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055672.1"
                     /translation="MRLDMDSMLYVLIYMTLLVSVIGSIFYFCKDLLNHKIKYVLIKN
                     IFVNRTTYSEERLPKQYIVFQKYDIWRYCSLF"
     gene            18374..19024
                     /locus_tag="PC592_001696"
     CDS             18374..19024
                     /locus_tag="PC592_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF4055673.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVNSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAMVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            19226..19897
                     /locus_tag="PC592_001697"
     CDS             19226..19897
                     /locus_tag="PC592_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055674.1"
                     /translation="MAKILVVEDEKRMQSIIVEYMQKGGYTCVTADDGVEALTILKSN
                     NIDLMILDVMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTGIPKNSLILGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            19894..21024
                     /locus_tag="PC592_001698"
     CDS             19894..21024
                     /locus_tag="PC592_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055675.1"
                     /translation="MSSLRKIIEKLKNLDISNWIKQNFGLHSVRKKVFLLSKLSGALI
                     ILFYLVVEELSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEADEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVVDKMRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLILFEIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVKNRDRGVEFYFMIPIDE"
     gene            21472..22317
                     /locus_tag="PC592_001699"
     CDS             21472..22317
                     /locus_tag="PC592_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055676.1"
                     /translation="MIKVEELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGNEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMAIDKPKNL
                     KMKNSNNKVEVEFVYNGSRDIKIVDIGELESGITFKYDEILSVHSKEATLEEVFIKYT
                     GRMLV"
     gene            22317..23345
                     /locus_tag="PC592_001700"
     CDS             22317..23345
                     /locus_tag="PC592_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055677.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSTSPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKEMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNVGFFEGIKILSQVLVQASILSIIMSLIGFGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYIQLKNAFFMNFSNELIYFVVCSLTIIVLFLLVKNIF
                     NKELVREG"
     gene            23348..24361
                     /locus_tag="PC592_001701"
     CDS             23348..24361
                     /locus_tag="PC592_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055678.1"
                     /translation="MIGLRYQLKSIRKDKMCIISFFLPVVMAILINFMGTIDMSSLGE
                     IHFGIVKDTLPVRTEQWLKKYGVLSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEILPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGVPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMLYIILDKKRKLS
                     FSR"
     gene            complement(24894..26144)
                     /gene="cme"
                     /locus_tag="PC592_001702"
     CDS             complement(24894..26144)
                     /gene="cme"
                     /locus_tag="PC592_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HDF4055679.1"
                     /translation="MENKNINSTWKKRVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTICSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINGSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVMSINNLIIVAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(26230..26976)
                     /locus_tag="PC592_001703"
     CDS             complement(26230..26976)
                     /locus_tag="PC592_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4055680.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELSLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAICLVNQYLKQLEIEKSN
                     AEEALTIVTQILNGHTPETDKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(27091..28113)
                     /locus_tag="PC592_001704"
     CDS             complement(27091..28113)
                     /locus_tag="PC592_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDF4055681.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKIIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSTGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGAGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIIE"
     gene            complement(28113..30533)
                     /locus_tag="PC592_001705"
     CDS             complement(28113..30533)
                     /locus_tag="PC592_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF4055682.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLKPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEVKNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDEFLKILLDQGNLSTFGTNLVNNILSKTRHLIESRLGHLSLYREI
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGIEGGQLVYQGNLEGLLQSNKSLTGQYLSGKYSMPN
                     RTSTKNITHIDEIPCITVQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQTNSSESEIGDEDDYAVVETIADRLIGTKYISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSDCHGKRFNDESLSIKYKNKTIHDILNMSISEAVNFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRVKLAKEIGKKRNGNILYVLDEPTTGLSLYDTAK
                     LIQLLDELVANGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(30619..31539)
                     /locus_tag="PC592_001706"
     CDS             complement(30619..31539)
                     /locus_tag="PC592_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4055683.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLFLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTITDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNVNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            32145..33059
                     /locus_tag="PC592_001707"
     CDS             32145..33059
                     /locus_tag="PC592_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF4055684.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSTSTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSENS
                     NTEILTGNSGIFKNIEKYLDVTINNNQKTMKYKHRDELFKNSNTNTYSRINEEHIDKG
                     YDSIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLNYESPESIHEIIIRKL
                     NSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEPTILF
                     GYEFESYLSEESSLSACNYGDMCYEDMY"
     gene            complement(33261..33881)
                     /locus_tag="PC592_001708"
     CDS             complement(33261..33881)
                     /locus_tag="PC592_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055685.1"
                     /translation="MFLINILLVDDHMLFSKSLSIALEEYEEIEQFYSTQDIHSLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGGTCFPSENTEVIIEDLTSMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIQMGYISPVY"
     gene            complement(33853..35436)
                     /locus_tag="PC592_001709"
     CDS             complement(33853..35436)
                     /locus_tag="PC592_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4055686.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTKTYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLVLDSWYLLLSFVATPIGTIIFKILSTVIAYVS
                     IKFIFLFLFQGSGYKFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHWKRVAFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRSIFLFISILVISLVVLFASGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPEVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNINDNGVKNTSFKTPLDITKITFDTIKHKGIISIKEQVENLGGTISISDNIPHGV
                     CVQITIPMKGDVSYKYFVS"
     gene            complement(35776..37803)
                     /locus_tag="PC592_001710"
     CDS             complement(35776..37803)
                     /locus_tag="PC592_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF4055687.1"
                     /translation="MNIFYMAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKVM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENILTCSGAFIIGLVLGALVHKSIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAISNGKFLYKTSLIKLIRYEKSTEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWISIGFYQIGLITMIIIVIGTVLFINSFLPYIMQKSKKNKRAFYTGTK
                     IITIPNFIYRIRSNSKTLIMLTLLSAATLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYMSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGASKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLIKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYLLLINGKETPVTVRETSLNNAISFANSVGTLIVNDSIYEQIAQSKFPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIASG
                     SILYFNNISAISDSTSDYKILQKMGYTNIQIKKIIKKQVLPFFNIPFLLGIVDCIFAT
                     LVYKTALMQNLLGNSLSQYIPVIIAIFLTSVVYLIYYIFTIKSCCKIVLKK"
     gene            complement(37816..38562)
                     /locus_tag="PC592_001711"
     CDS             complement(37816..38562)
                     /locus_tag="PC592_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055688.1"
                     /translation="MNTILKVNSITKTYKGQQPSLDKVSFNVSEGEFIGIMGASGSGK
                     TTLLNVLSTIDKPTSGDIFINNINLKSLNDTNAADFRKDNLGFIFQEYFLLDSLTTFE
                     NISVPLTLQKLSPDKIEKMVKSLAERFGIASQLNKYPNELSGGQRQRTSAVRAIVKQP
                     SILFADEPTGALDSNSATELLHSLQEANKELKTTILMVTHDAYAASFANRILIFKDGH
                     IIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            complement(38853..40514)
                     /locus_tag="PC592_001712"
     CDS             complement(38853..40514)
                     /locus_tag="PC592_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HDF4055689.1"
                     /translation="MNKKNLAILISGIMFFSSSSSIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIESSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKALNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSVNFLNSRSIKKSYIVGGNKILSD
                     NAVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGISQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIENKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQTLPGSDILVCYYDEDDNEYDCKVVKDNVLYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTKNISLDKAKAIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIIDIDMDNDSDDDIDDNDNNHNNNSNTNDNSSIISAEKAKSIILDKVP
                     GGKIVKFKYDEDDKEYKGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            41113..41550
                     /locus_tag="PC592_001713"
                     /pseudo
     CDS             41113..41550
                     /locus_tag="PC592_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
BASE COUNT        15295 a         5043 c         6630 g        14640 t
ORIGIN      
        1 aattttaaat aaatgtttta ttctcaaaat atgcatatta atttaataaa atataccaaa
       61 atgggaataa aaaataaatt ttatgagaat ttaataacta ataattaata tatttaggtt
      121 ataataaata tgtgcgtaaa atctaataat aagcaataat acagtaaatt taggaggaat
      181 aatatggata ctttaaagga actttttaaa ataggaagtg gaccttcaag ttctcatact
      241 atggggccac aaagagcagc agagagattt aaaaatgaaa acccagatgc agaaagtttt
      301 agagcaatat tgtatggtag tttggcagct acagggaagg gtcacttaac tgactatata
      361 attgaaaaaa ctatagcacc taaaaaagtt gaaattgttt gggaagaaga tattataaaa
      421 gattttcacc caaatgggat gaagtttgaa gctttagata aagataaaaa tgtaacagct
      481 gaatggactg tatattctgt aggaggaggg actatagcag aagaaggtca aagaaacagt
      541 aaaagcaata gtatatatca cttagatact atggatgaaa tagtaaagtg gtgtaaagaa
      601 aataataaga ctttggtaga ttttgtcttg gaatgtgaac caaaagacat aaaagattat
      661 ataaaaacta taaaagatgc tatgagaaaa tctattgatg atggactaag tacagatgaa
      721 ataataccag gcaaactatt attaaaaaga agagcaagta cattttataa tgcatataaa
      781 aaagataaga gtttctcaac gcttgtatat gcatatgcat tagcagcttc agagcaaaac
      841 gcttctggta atataatcgt tacagcacca acttgtggtt ctgctggagt aataccagga
      901 atattctttg caatgcagga tttctataat tatgatgacg aaaaaataat tgaagcacta
      961 cttgtagctg gaataatagg taatataata aaaactaacg cttcaatatc tggagcagag
     1021 gtagggtgtc aaggtgaagt tggagcagct tgttctatgg cagcggcggc agtagcatac
     1081 ttaaagggtg gaactataga ccatattgaa tatgcggcag aaatagcact tgaacatcat
     1141 ttaggaatga cttgtgaccc tgtatatggg tatgtacaaa ttccatgtat agaaagaaat
     1201 gctatggcag ctcaaagagc ttatgatgca gctaattatg cattattaac tgatggctca
     1261 cattctgtct ccttagacca agttgttgaa acaatgaaag aaactggtat agatatgatg
     1321 gataaataca aagaaacagc taagggtgga cttgctaaac atttcttctc ttgctaaaaa
     1381 taaaattttc caataataat tcccctgttt tgatttatga aacaggggaa ttattattaa
     1441 tggtgaatta tttaataatg caaaatattt ttatattcat ttagtttttt atttttaatt
     1501 agtataacat gttatataat attttaatta taaagaaata tagaaatatt ttttaataaa
     1561 ttagaaattg gaggagatta catgagagag gcatcatatt tacaagaaca actttataaa
     1621 cataggaagt cattaaatcc tattgcagag attgggagaa aagagtataa gacttcaaag
     1681 tatataagag attaccttga taaattggga attgagtatg aaatttattt agaaacaggt
     1741 atagtaggtg taatagaagg taaaagacct aaaaaagata ttgcttttag agctgacata
     1801 gatggtcttc atagtgaaga aggggtaaaa catttatgtg gtcatgatgg acatgctact
     1861 atattacttg gattaattga gtatttaaat gataataaag aagacttaaa tgataatata
     1921 gtatttatat tccaaccagc agaagaaggt cctggggggg caaaagctct aatagatgaa
     1981 ggcgtgctta gaaaatacaa tgttgatgaa atatatgggc ttcatatata tccagagtta
     2041 ccagaaggtt atgtaggtac aagagaaggc tattttatgg ctcaaatagg agatattgat
     2101 atagaaatag tgtctaaaag tggacatgga gctatgccac aaaatggtat tgatggtata
     2161 gtgatagctt caaattttgt aaactcactc caaactatag tgtctaggaa tataagtcca
     2221 atagacaatg cagtgttaac tattggtaga attgaagggg gagctagaag aaatataata
     2281 gctgaaaata taaagatgga aggcactatg agatgcttta gcccagaagt ttatgagaaa
     2341 atgaagctta gagttagaga acttgctaga gggtttgaat tggcttataa ctgtaaggtt
     2401 aatataaata ttatagatga ttatattgct gttaaaaatg acaaggattt gtatcaagag
     2461 tttgtagagg ctgttggaag tgatactgtt gtagagttag agccacttat gatatcagaa
     2521 gatttttctt attatcaaaa agaagtacca ggattatttt ttatgttggg ttcaagaaac
     2581 gaagaaaaag gatttgtaaa tggtcttcat aatataaatt ttaattttga tgaaaagata
     2641 tgtgtaaatg cattgaatgt ttattcagcg ttattaaaat acaaagaggc gatagattag
     2701 aaagataaat tataaagatt aaaaagtaga aatacctaaa tttaaaaaaa gtgtagtgat
     2761 aaatacccct tacatatttg tataaattta ttttaattga caaaaataca aataagaagg
     2821 ggtgattttt ttgaaagaaa aagtacaaat agaaaagaag ataactaatg gcaagaatac
     2881 taaaatattg acaaatgatg atataatgaa atatgagata gcctcagaac taggtcttat
     2941 ggacaaagtt ggtgaacgtg gatgggcagg tcttacagct aaggaagcag gaagaattgg
     3001 aggtatgctt acatcacgca aaaagaggct gaaaaagatt gtggaggagc agaataaaaa
     3061 ggatgagtca atatagtgat tttgcgtttg tatatgatga acttatgaat gaagttgatt
     3121 atgatggatg ggttaaatat atagaagata taatagatag tgaaggtgta aaagtaaaaa
     3181 atatattgga attggcgtgt ggtacgggta atcttacaat tccattgact aagaaggatt
     3241 acgatatagc tggtatcgat atatctgatg agatgcttag tgtagcaaaa gaaaaggctg
     3301 aaaaagaagg agtagaatta gttttacttc aacaggatat atcagagctt gattttgaaa
     3361 tatctgattt ggactgtgta ctttgtgctt gtgatggatt caattatata acttatgatg
     3421 atgatttgga aaatgtattt tcaaagacat atgaattatt aaagcaagat gggatattta
     3481 tatttgatat aagttcattt tataaattag ccaacatatt gggaaataat atgtatggag
     3541 aaaatagaga agatatagcg tatatgtggc aaaattactt tgatgaagaa gagaatataa
     3601 ttgaaatgga acttacattt tttattaaag atgagtgtgg aaagtttgaa agatttgaag
     3661 agatacacca acaaagagca tatactgaag atgagatagt tgatatgctt aaagagtctg
     3721 gatttaaaga tataaaatct tatggagatt ttacatttga taaacccaag gaagaaagtc
     3781 aaagaatctt ttttgtatgt aaaaaataag atatttttgg atataaaaga aacttattaa
     3841 aaataagcat tatataaaaa tataaaaaat gcagttttat agattaaaaa taaagtgatg
     3901 atattttatg atttatgatt tttaatagtt ataaagttct atagattaaa attagaataa
     3961 aagaactatt acctagtaaa attaaaataa aagagctatt acctacgatt aagatagata
     4021 agtatttata gagtagaatt aagatagtaa tatagtaaaa tgagataatt aacgaaatat
     4081 ggaggaatat tgatgagaga ttatgtacta agagcgacat caggaaatgg gcaagttaga
     4141 gcatttgtcg caactactag aaatacagta gaggaagcta gaagattaca tgaaactaca
     4201 aaagtagcaa cagcagcact tggaagaaca ttaacagcca catctataat gggattaatg
     4261 atgaaaaatg atagtgataa attgactgta ataataaagg gtggaggtcc aattggaact
     4321 attatcgcca catcagattc taagggaatg gtaaaaggat atgtaggaaa tccgcaagta
     4381 gaggttgaag actatccaaa tggaaagtta aatgtagcag cagcagtagg tacagaaggt
     4441 gttgtaaaag ttataaaaga cttaggtctt agagaaccat ataatgggac ttatccattg
     4501 gtaagtggag aaattgcaga agactttact tattattttg ctgtatcaga gcagactcca
     4561 tcagtagtag ctttaggtgt tcttacaaaa gaagatgaag tagagtttgc tggaggattt
     4621 atagtgcaat taatgccaga tgcagaagaa gagactattg ctaagttaga ggaaaatgta
     4681 gctaaattac cttctataac taacatgtta aaagaaggaa aatcaccaga ggatatatta
     4741 aatattgttt tagatggttt ggagcccaaa atacttgata cctgtgaagt tgggtttatg
     4801 tgtgaatgtt caaaagaaag agtaaaaact gctttggttg caatcggtaa aaaatcattg
     4861 gctcaaataa tagaagaaga taaaaaagca gaagttggtt gccagttctg taataagaag
     4921 tatatgtata ctgaagaaga gttgcttgaa attttaaagg aaatgtagac tataaaaata
     4981 ggtgcattga tatagtagta tcatagtgac atagtaatgt cttacttata taggaattaa
     5041 aatataattt attaataata gatatatttc tattaaaaaa taagtttaat aaatttttaa
     5101 gcttaataaa ttttaagaat tgagaagctt tttagctgta atatttgcaa tgttgcagtt
     5161 agaaagcttt tttattttat tatagttcgt gtcaaagatt gtatgaaaca ataaaatatt
     5221 gtaaaataat ttgtatattt aaacctagtt gccacaaagg tttataagat atttgaattg
     5281 attatgcgaa attctatgaa gtagtaaccc tgtgacttta atcatgggag attcagaaga
     5341 aggagaaaat tttaaatatg gaaagcaaaa ctaagcacat aggaataagt atattaatat
     5401 tattgatgat atttttaatt gcaaagaatt ttaatggaaa acttgaaata cctattcctg
     5461 agagtaatag tagaaaattt aaatcagcag cagtatttta tcctcaacat caggatgatg
     5521 aggttttatg gggaggaagt gctattgtag atgctataaa acagtgtggt gttgataatg
     5581 tatatgtggt attagtatca gatggttctg gagttaacgt tttcaaagct aacacaaaat
     5641 ttagaaactt aactaggaag caaaaggagg aacttagaaa taacgagttt aaatcagctt
     5701 tgagaaagct tggagtgaaa cctcaaaatg tgattatact tgcggatata gataaaaagg
     5761 agggtacaca ttatgaatta atgaaaaaga ctatattgga ttttgagcat aaatttaaag
     5821 gtaatgtgac ccatatagcc catcattata agtatgatga ccatataatg catagaaaga
     5881 atggggaagt tttaaagaaa cttaaacgtg aacacaagat aaaagatgac ttatatttta
     5941 ttaagccaaa atacgtaaag tatataccaa gaaatgaaag agctatatat aaggcaatgg
     6001 agtttgatga ctataacaag gttaagagtg cttgttatga atataaggtt gtaaattcaa
     6061 agcgtaaaat gtatggtata ggatatattt cggcacatag ttattttgaa catcttttaa
     6121 atgaccctga acttacgtct gtattaagtg aagattaatt tcttataagt agtaagttat
     6181 gtttgataag ttgattagag ttttctatag tttcgaaggt attgaaaatt tagttttatt
     6241 taaaaattta aagatagagg tttttaatgt ctggtatttt aaagttaagt tgaataattg
     6301 tatagaatta tttgtgaaag aagaaacagt gtaaaacata gtatcttatt tatggtttta
     6361 aaatcatagg taagatactt tttttatgta actaatacca ttttgtgatt gttaacttaa
     6421 gagttttata taatttaaca ctcatatata atgatgatat ttatgtagaa taaatgcaat
     6481 tacgcttaaa taaaataact gtatttttta tagaaatcaa accctacact atactaccag
     6541 ataaaatcta catgctataa tttgacctgt gtttataaaa aaaggagtaa tctaataaaa
     6601 tagtatttta tttatgtata actaacaact attattacga tttactctaa agaatttaaa
     6661 gaaaaataat gcaggaggta gaatatgaac aatgaattta taattttaaa aggatgcaaa
     6721 gagaataatt taaacaatat ttccttaaaa ataccaaaaa gaaaaataac tatatttaca
     6781 ggggtgtcag gttctggaaa atcatctatt gtatttgaga caattgcaaa agaatcacaa
     6841 cgccaactaa atgaaaggtt tagtacattt gtaagaagtt ttttaccaaa atatggagag
     6901 gttaaagctg attgtataga aaatctgtca acaccaatta tcatagacca aagtagactt
     6961 ggtggaaatt caaggtcaac tctaggtact attacagatg taaattcttt tttaagagct
     7021 ttatattcaa ggtttggtag tgagtatata ggtaatgcta atatgttttc ttttaatgat
     7081 attgatggta tgtgtccaca ctgccatggg cttggaaaaa agctagttcc taatatgaat
     7141 caaattcttg atatgaataa atcattaaat gaaggtgcta tattgctttc agggtttgga
     7201 gtgggttctt ggcattggaa tatattttct gaatcaggtt tttttgatat taataagagg
     7261 atatgtgatt attcagaagt agaattggaa aagtttttgc atggtaaagc agaaaagatt
     7321 aagatagaaa atgctggtca aactaacatg acatatgagg gattaatggt taaatttaat
     7381 cgcctgtacc taagtagaga gggagaaata tctgaagcta ctaagaaaaa attgagtaaa
     7441 cttcttatag aagataggtg tcctatatgt gatggaagaa gacttaatga aagagtatat
     7501 aagtctttaa ttaatggtta taatatagca gatttaacta gtatgcaaat tgatgaattg
     7561 gttgaagtta ttaaaagtat agatgagcca gaagcacaac ctttaattaa aggaataata
     7621 gaaaagttaa acagtatcat agatataggt cttggatatt taacactgga tagagagaca
     7681 tcttctctat caggaggaga atctcagcgt ataaagatgg ttaagtattt aaatagtaat
     7741 cttgttgatt taatgtatat ttttgatgaa ccaagtgtag gacttcatcc aaaagatgtg
     7801 tataaattaa ataatctttt aaaaaaattg cgtgataaag ggaatacaat tatagttgtt
     7861 gaacatgacc cagatgttat taagattgca gaccatattg tagatgtagg accaaaggca
     7921 ggtaagtatg gtggagaagt tgtgtatgaa ggcagttatg aaaatctact tacaagtggt
     7981 acgttgacag ggaatgcttt aagtaaattt cttcctatta aagaaagtgt aagagagcat
     8041 agaggatatt tagaagttaa aaattgtaat aaaaacaatt taaaaaatgt atctattaag
     8101 atacctaaag gcgtattgac tctggttact ggagtagcag gagcaggtaa aagtacgttg
     8161 attaaggatg aatttttaaa gcaaaatcct aatgctgtac ttatagacca aagccctgtt
     8221 tcagcaaatt caaggtcgag tttggcaaca tatagtggaa ttatgaacaa cataagaagc
     8281 atattttcaa aaacaaatgg cgtaaatgct tctttattca gttcaaattc agaaggagct
     8341 tgtgataact gtaagggttc tggaatagta gaaatgaatc ttgcttttat ggagagcata
     8401 aagagtactt gtaatatttg tgaaggtaaa aaatttaaaa aagaagtttt agaatataga
     8461 tttcaaggga agaatataat tgaagttctt gaaatgtctg ttttagatgc aattgagttt
     8521 tttaatttaa aacagattaa aacgaaatta caatgtattg aaaaaatggg tattggatac
     8581 cttactttag gacaaactct tgatactttg tctggaggag agtgtcaaag attaaagctt
     8641 gctagtgaat taaataagga aagttcagtg tatatattag atgaaccaac aacaggtctt
     8701 catatggctg atattgagaa ttttataggt ataattgaag aaattgtaga taatggaaat
     8761 acggtcataa taattgaaca caatatagat gtaattaaaa gagctgattg gattattgag
     8821 atgggacctg aaggaggaac aaaaggtggg agagtaatat ttgaaggtat tccaaaacaa
     8881 ttatgtaaca ataaaatatc attaacagca aaatatatag tataataaat aaaatataat
     8941 aaatttataa tgatatttta ataaatataa tgggtgtata aaatgataat taaacttaac
     9001 agtaataaat aatgtgagaa atattcaaat ttaattaaat aaagtgtcag aaatttgttt
     9061 aaattttagc atttcaacag ttctgacctt ttttcttatt tttatggaga atatcgagaa
     9121 tggagtctct aatagttact ttttttgtct acttgcaagt ttgattaaaa aatgtctatg
     9181 cacacttgtg actttagtca tggaaggctc agaatataat cttaatatat aatttgtgaa
     9241 ataatttgat tacgatttgc tgatgtataa acaataaaga ttaactacat taaaatttaa
     9301 atcttgttaa gtaaaacata taaaaggaga gagatgaatg ataaatgata ttctaacatt
     9361 attatctgaa agaagtgatt tttttataaa gctatccata gaacatttga tgatttctat
     9421 tatttctata ataattgcga ttgttttggg tggtataatt ggtattattg taagtgaatt
     9481 tcataattct tctaaaccta tattgggaac tatcaatttt ctatacacca ttccatctat
     9541 ttctatgcta ggatttctga taccattttc tggaataggg aatactactg ctgttattgc
     9601 acttaccatt tatgcattat tacccatggt tagaaataca tatactggaa ttaccaatgt
     9661 ggataaaaat attcttgaag cagctagagg aatgggaagt acagattttc agatattgta
     9721 taaaataaaa cttccattag ctctacctgt tattatgtct ggtattagaa atatggtaat
     9781 tatgacaatt gcattagctg gtatcgcttc atttataggt gctggaggct taggtgtagc
     9841 tatatataga ggaatcacga caaataacac ggtaatgaca attactggaa gtatacttat
     9901 tgctctatta gctttaatat ttgattttat tttagggctg gtagaaagat tttttcaacg
     9961 aaaaagaaaa aagaaaaata gaaaaaaagt ttttgccatt ctaggaagcc ttattcttat
    10021 agtaactatc tttacatctt atttatttaa tccttcaaag actcaaacta ttcacattgc
    10081 cacaaaacct atgactgaac aatatattct tggagagatg ttggatattt taattgaaaa
    10141 aaacacaggt ctaaaagtgg aaattacaca aggtgtagga ggaggaacat ctaatattca
    10201 gccagctatg gaaaatggag aatttgatat ttatccagag tatacaggta caggttggaa
    10261 tatggtactt aagaaaaatg aattatatac tgaaaatatg ttcagtaaac tacagtcaga
    10321 atacaaaaat aaacttaaaa tgcaatggac tggtatgtat ggtttttcta atagctatgc
    10381 attagcagtt agaaaagaag ttgcagataa atataattta aaaaatatat ccgacttaaa
    10441 agatgtatct tctaaattga catttggagc tgaatatgac ttttatgaga gagaggacgg
    10501 atatactcca ttatgtaata catatggact gaactttaaa gatacagttg atttagatat
    10561 tggattaaaa taccaagcta tcaatgaagg taagattgat gtaatgccta tatttacaac
    10621 tgatggtcag tatagtgttt cagatgttat agttctaaaa gatgataaaa atttctatcc
    10681 atcttatcaa tgtggaaatg ttgttcgttt ggaggtgtta gaggaaaatc cagagctatc
    10741 aaaggtattt aagatggttg gagatatttt gactgataaa gaaatggcta aaatgaatta
    10801 tgacgtagaa aacaacaatt tagaacctag agaagttgct cgtgagtttc tgaataagaa
    10861 aggtctttta taaattggag gaaatgtaat gacaactatt atacaattta aaaatattaa
    10921 aaaacaatat aatgataaaa ctataataga taatcttaat ttagatatag aaaaaggaga
    10981 gtttttgact gtcattggtt cgtctggttc tggtaagaca acactcttaa aaatgattaa
    11041 tggtttgatt ttgccagatg gaggaaatat tttgataaac caaacagata tcaaaaacga
    11101 ggatttaatt aaattaagaa gaagaatagg gtactgtgta cagggaagtg ttctttttcc
    11161 tcatatgact gttgaagaaa atatttcata tgtaccaaat cttctaagta aaaaaaataa
    11221 attagaagta aaaagagctg tagacaaatg gatggaaata gtgggattgc caaatgatat
    11281 gaaagtacgt tacccatcag aattgtcagg tggtcaacaa caacgtgtag ggattgcaag
    11341 agccttagct tcttctccag aaattttatt aatggatgaa ccttttggtg cagttgatga
    11401 gattacacga aagcaattac aaaaagagat aaaagaaatt cataaaaaaa caggagttac
    11461 gattatcttt attacacatg atatttatga ggctttgatt ttgggaacaa agactttggt
    11521 attaaatcat ggagttgttc aacagtatga tactcctgag aatattttaa atgctcctgc
    11581 taatcaattt gtagaccagt tattgaatat aagaaaatct ataatagatg atgagaattt
    11641 aaaaaaataa atttaaattt aaaatcaaat tgttgtgata aaagctattg acctagagtt
    11701 aacttcaagt tgtatattgg tactaaataa tagatttaat tttgcaaagg ataaggtgtt
    11761 ttaataaaaa tgaatgtaga aaacgaatta cttaaaaact tagatagatt gcatacaaca
    11821 gagttaggtg ttgtaagaat taagaaaaat ctttctttgg atacaaatga tgtagtgaac
    11881 tggtgtaaaa ctaaaataga atctccaaat gccattatta atagaaaggg aaaaaactgg
    11941 tatataagta tatatgattg tattataacg gtaaatgctc acagttatac aatcattaca
    12001 gctcataaag aaaagaaatg aaatgaattg caaaatacaa aggtcaagag cattttccat
    12061 tgtttgtagt acctatgaag aagtatataa aataatatta cttttgagta ataatttaaa
    12121 ttttggagat tgaaaaattg aatatactga tttacatcag taccttgttg gagcgacttg
    12181 gattttacaa aaagaatatg ataaatatta gactagataa tcaatgttgt agtgaattat
    12241 tccatgtcta gtgaatataa ataacataaa aaaccgtcaa gatgaatagt ttattcgtgc
    12301 ttgacggttt ttagtatttg ttgaagtaaa attttatttc tttagtatat cacttttagt
    12361 caaaccattt gatttagctt gagtattcca ctgatgatta cctataagtt tatataggaa
    12421 tctaggaaaa ttaggtgaaa taaaaatatt atttttcttg gaattaccta tatttatatt
    12481 attactaagt atattttttg aaagttcttt taatgcaatt cctaaatctt ttttttgacc
    12541 tttacccaaa ggtacagatt ctagtgaacc aaacatctca ccagctccaa ttccaatacc
    12601 ttgaatccat gtaaagttga tttttttaca ccaatgctct atcatttgaa ttgccaaatg
    12661 attatgttca ccttcattga atccacagtt aactattgca tacactggaa taggtttttt
    12721 attttgtgtt tttaaaaatt tttcacattc ctctaaaaaa tgaagtaaat gagatggaat
    12781 agcatctaca taaagaggaa atgcgattat taatctatca caattaagta tggcattaag
    12841 agcatcagga tacttagatg tgttatctac tttaaatgta aaaactttat tgtcattttg
    12901 aataagttgt tttacttcgg ataaaaaata ctgtgaatta tttttattta cttttggact
    12961 accatttatc attactatat tcatatggac tcacctctta tatcttgtat attttcatag
    13021 aaacaaacag agtgttcttt tatattgaaa tttatagcat ttccatttac taatttcgta
    13081 gcagtttctt tttcagattc tgtaatacaa tttccataga atatagcttc taaatttata
    13141 tgtttgtcgt atctactttt atgacgcatc atattatctt ttatcacaaa gtatggaaga
    13201 atataattaa tacttttatc aagtacgttt ttgacaaaag ggctaaaccc tccgtaacag
    13261 catctgctta ttataataat tccatcagat tcatttataa gtttacccat gttgctgtaa
    13321 taatctttta caacacactc agtaggagtt ttaatccagc aaccaaaaca acctatacat
    13381 ttgtggattt cttttgtgtt tggaagtatt tttatattgt catcaagttt gggtaatagc
    13441 ttttctaatt cttcatcagt taaatcgtgt attaaaagct tcataaaatc catctccttt
    13501 tattatgtat gtttacttct aaaaatcata tcttataaat ttttcagtaa atctttacac
    13561 caattaatta caaaattata atagtcaact ccataaatca ttgtggcata catatatgta
    13621 tattggtcaa cacaatgatt ttcttctaca tcaatttttt gtttacttaa tttatttaga
    13681 agtaattcta cttcagttat tagcattttt aagtttgttt caattatttc tttgggtaga
    13741 tacttgtaaa agaatatatt aacaaggtgg ttttgctttg ttttagaaaa atttataggt
    13801 ttctttaacc actcaagaaa tacttcttta ccagtattag ttatggagta tagttttttt
    13861 aatttgctac catctataac ttcgtgatag tgtatatatc cttttgtttc taatctttta
    13921 agtgcaggat agatactgcc aaagctagcg tcaaaaaagt acgaggtact ctctgacatt
    13981 atttgtttta agtcgtatcc acttaattct ttttccatta aaaatcctaa aataatgtat
    14041 tctaacatgt tgcctcctag tatcaattag atatatatca attcgatata tttattattg
    14101 cagataataa atattacgtc aagatgcttt ttaaaataag ctaaaaagaa ttagaaatta
    14161 ttaataaaga tgtaaaaaaa ttaatataaa aggtaattaa atatcaatga agatttaaaa
    14221 atagttaaat caaagtaaga gtctaatata taaaatttat agtaacttta tggtttaaat
    14281 ataaacctgt gtgctattga caaagtataa aattagcagt aaaatgattg catgagcaaa
    14341 tagattattg cgaacgcaaa aagataagga caatagatat taaaggagag aatatgagag
    14401 agctattaaa atgggtttcc attataaata gatacaatac aaattatatt gacaggaaat
    14461 tggcggatat tggaatcaac aatagccaat atttttatgt attacacata tgtaataatc
    14521 caggtattac acaggatact atatttgaga aaattcttgt gaatcctagt aatataacaa
    14581 gagctttggc aaatttagaa aaagaaggtt ttataacaag agaaccaggt gtaaaggata
    14641 aaagaacatg gcatttatat cctacagaaa aatctttaga atgttatgat gaaatactaa
    14701 aaataacaaa tgggtatgtt gaggagttgt tgagttcatt tgagaaagaa gagcaagagt
    14761 tgtttatgtc aatgttaaaa aaagttgcat ttttggctat tgatatgaat gaagaagcaa
    14821 aattggaggc gaaggaaaat ggaagaaaaa tataaggagc cattggaata tgaaaaagtt
    14881 tcaaagttat taaccaagta cgcaattcct agtattatag caatgttagt aagtgcttta
    14941 tataacattg ttgaccaaat atttattggg caaggtgttg gtgtattggg taatgctgct
    15001 acaaatgtca cttttccgct aacaacaata tgtactgcaa ttgcattatt gttaggaatt
    15061 ggaggagcgt ctaagtgttc attggaatta ggtgctaaaa attcagaaaa agctacaaaa
    15121 gcagcaggaa attctatatg cttgatggct gtttttggaa taagtttatt tataatagta
    15181 tcaatatttt taacaccact attaaaattc tttggctcta catcagaaat actaccttat
    15241 gcacacacat atacaaaaat tacatcaatt ggattaccat ttcttataat gtccactgga
    15301 atgagtaagt tgatacttgc agatggaaga ccaaaagctt ctatgttttg tatgttaata
    15361 ggagcagtta ttaatacaat tttgaatcca ttattcattt ttgtttttaa tatgggaatt
    15421 gctgggtctg ctttagcaac tgttattggg caacttatat cttttggaat tagtgttcat
    15481 tatataaaga attttcaaca tattaaatta cataagaaaa gttttaaatt agatagtata
    15541 atttataaac atatatttgc actaggttca agttcatgtt ttaaccaatt agcaatgact
    15601 gtaacacaga tagttatgaa taatacattg gcttattatg gggctaggtc agtttatgga
    15661 agtgagattc cacttgcctg tgttggtatc attattaaag taaatatgat ttttatatct
    15721 ataattattg gtatatcaca aggtatgcaa ccaattatag ggtataatta tggggctgaa
    15781 aagtataatc gtgtaaaaga agcgtataag tttgcagtgg gaagtgcaac tattatatct
    15841 gttattgcat tcttatgttt ccaatttttc ccaagacaaa ttacgtctat atttggtaac
    15901 ggaaacgaga cttattttat atttgcagaa cattatttta gaactttctt gttcttaaca
    15961 tttataaatg gtgttcaaat agtatcatca actttcttta catcaattgg taaatcagtg
    16021 ttgggacttt ttacttcttt gactcgtcaa attttatttt taattccatt gatagtgatt
    16081 ttaccaatgt ttatggggat tgatggagta atgtttgcag gaccaatagc agatgcagcg
    16141 gcggcaatgg tatgtatata ctttgcagtt catgaaatga aatcattgac tataaagcaa
    16201 aataatttga tgagtaacca taataagatt gcagaggtat aagacaatat ttaagaagta
    16261 tagaaaatta atttaagaag tataataagc taatttaaag aagtataatg agctaactta
    16321 agaaatatag aaaattaatt taaagaaata taataaatta atttaggaaa tatagaaaat
    16381 taatctaaag aagtataata aactaattta agaaacatag aaaattaatt taaagaaata
    16441 caataaatta acttttaagt aacattaaat taatgtaagt aaaataacgt tcatgtgaag
    16501 atttaaaggt gcattttctg gagctaagta tatgttgtag agtgtatatc tctctagtct
    16561 gtgaagttta atagctcaag aaaatgcact atttatgatg cttattttgt tttatttcca
    16621 attttagaaa taactattct aattaaatct aaaattatac cataaataag aaaagaaagt
    16681 atagatgcta tgtaccaata aatcgaaatt gaccctgtaa ttgttctaca tgggatttgc
    16741 atacctgaat ccataaaaat aaaaaaacta tcaattctgg aaataataga caaaatagga
    16801 ttgaaaccta ttagaataat actttttgag tcttgaccaa tttgatgcat agaaatctca
    16861 aacaatgcaa ttaaaaaaaa ccaaaatgta aaagatttaa taattttttt catcaaaata
    16921 cctcacctaa tataaattct gtttgcacta tttgcttact ataactattt atctccattc
    16981 agttacatca tttaattgta atctaggtct tcttgatggt tcttcatcag gataccccaa
    17041 agatattgct gccactaatt gactatctgt attcaaccat tcacataatt cacgatatgc
    17101 aaagtataca tcacaaatcc aaagactacc tagacctaat tccacggctt taagcgacat
    17161 attttgaatt gaagctccaa ttgattgaat gtttgccatt tcatagaatc gttcttcagg
    17221 ggatagattt tctaaaagtg acttacctag tatatttaaa ataaaaattg ttactggagc
    17281 ttgtttcatg atttcaaccg tgtaatttgc accagagata tgttgacgac ttcctggaag
    17341 aagcccatta tcatcaattt cgttttgaat acctttgctc atggctttaa gcatagattc
    17401 tttttccttt tcagtgatga caacaaaacg ccatggttgc ctgtttttag atgaaggtgc
    17461 atttattcca gcttcaatta ttttctctat agtttcatgt gaaatgcttt gatttttata
    17521 ttttctgata cttcgtcttt ttgatataga atcacttatc attttaagta acctccgttt
    17581 attttttgga aaaatatatt tgttttctat ttttaattat tttagcatta atcagaaaaa
    17641 aagtcattga ttttagtata caattattaa tgattgtatt aagaattgca tcaaaaagta
    17701 tgtgattata ctaagggatt atattagaca ttatatttaa aattgtatta aaggttgtat
    17761 ttaatattat attaagattt atattatatt gggtcttata ttaaattaag gattataaat
    17821 tgaaaataag ctataaaaac tcaatattgt tttgttcaga gataaaaaaa gaatgcctta
    17881 ggtgattttt attaaaaatt aagagtgata agattatata ctttataaat gtaaatatga
    17941 cgaataaaaa tgataaatat aataatctat atatttacat taggagtttt ctatactata
    18001 attatttaaa actaaatata aatgttggaa ttatttagga cttgaaattg tttaaaaata
    18061 aatataagtg atgaagaggt gatgtgatga gattagatat ggatagtatg ttatatgtac
    18121 taatttatat gacattattg gtatctgtca ttggaagtat attttatttt tgtaaagacc
    18181 tcttaaatca taaaattaag tatgttttaa taaaaaacat atttgtaaat agaactacat
    18241 attctgaaga aaggttgcct aaacagtata tagtttttca gaaatatgat atttggaggt
    18301 attgtagttt gttttagttt gaaatgaatc tattataaat tctaaagttt aaaaataaaa
    18361 gggagagaat aaaatggatt tcatttcaag tatattgcaa ggattattaa gtatattatt
    18421 taattttaca ggtgattttg ggatttctat agtacttata actttaatag ttaaattagt
    18481 acttatgcca ctatcattaa aacaaagatt ttctgtaaaa aaacagcaag aattagctga
    18541 aaaaatggaa catataaaag aaaagtataa gaatgatact aaagaactgg aaaagcaaat
    18601 acaagtaaat tctgtagaaa gtatgaagag tatgctggga tgtcttatag ttttagtaca
    18661 aatgccagta gtatatgctt tatatcatgt atgtttagat atgacaaagg aatttacaac
    18721 aattataatt ccatggattg ctaatttagg tacatttgac aatttgttta tattaccttg
    18781 tatatatacg ttaattatgt tagcttcaaa tttagtgaat tatataccgt acttaaaaat
    18841 aaattctcag gtaaagttta acaaacaaat ggctatggtg actactataa caagtcttat
    18901 actgactgtt agaactccag tagccatagg tctgtacttt ataacaagtg caatttattc
    18961 attaattgaa gatatttgtt ttagaatata ttttaatcga aaaaatagaa ttgtgacaaa
    19021 ataatataat tattattaga aatattttag cctgctaaca taggaaaagt tagtaggcta
    19081 tttttatcta tgatatcaat tccattaaga atagtctaaa aaatactatc aaaatactat
    19141 ccaaatacta taaaaaaata gttgaaaaat aaataaatta atataaacta aaataaagcc
    19201 tacaaaaaag aggtgataaa tagaaatggc taaaatacta gttgtagaag atgaaaaaag
    19261 gatgcaaagt attattgtag aatatatgca aaagggagga tatacttgtg taactgctga
    19321 tgatggagtc gaggcactta caatattaaa gagcaacaat atagatttaa tgatattgga
    19381 tgttatgatg ccgtatttag atggattttc agtgtgtaga gtttcacgtg aaatgactaa
    19441 tatacccatt attatattga cagctaaagg tgaagaggag gacaaattaa agggttatga
    19501 atatggtgca gatgattata taacaaaacc atttagccca aaagtacttt tagcaaaagt
    19561 taatgccttg ttacgtagat atactactgg cattccaaaa aattcattga ttttaggaaa
    19621 gatttttatt atggtagcat caaggcaagt atatgtagaa gataaattga ttgatttaac
    19681 atataaagaa tttgaattat tgcgtttatt tatggagaat ccaaatcaag ttttttccag
    19741 agagaaactt ttaaattgta tatggggata tgattttgaa ggaaacacac gaactgtaga
    19801 tacacatata aagaccttac gcaaaaagct tggtagtgaa gggcatcata tagttacatt
    19861 aattcgttca ggatataagt ttgaggttaa ggaatgagta gtttaagaaa gattatagaa
    19921 aaattgaaaa atttagatat ttcaaattgg attaaacaaa attttggact acattcagtt
    19981 agaaaaaaag tgtttttact ttctaaatta tcaggggcgt taatcatact attttatctg
    20041 gttgttgaag aactttcgat aaactctaaa tttgaatttt ggatttggtt tataatactg
    20101 gttatattta ttatgagtat tgatttttta ttgggaaaat ttatttcaga accaatcaca
    20161 tccataaata aatctgcaaa aagcatgtct caacttgatt tttctaatcc atgtactgta
    20221 aatactaatg atgaatttgg agaactttct aggagcttga atacaatgtc tacaaatcta
    20281 caacaggcat tatcagacct agaaagtgca aatattcaac ttgaaaagga tgtaaataag
    20341 gaaagaatgc tattggaaca aagaaaggag ttggtagata caatttcaca tgaaatgaag
    20401 actccacttg gcattatacg tgcgtataca gaggggctta tggatgaagc tgatgaagaa
    20461 aaaaagaaaa attatatgaa tgttataata gaagaaactg atagaatgaa caatatgatt
    20521 gtatcattat tagacttatc tgcattggaa gcaggagttt ctaaacttaa cccagagcgt
    20581 tttgatttta tagagtttgt tgaaactgtg gcaggtcgtc ttttaattga tataccagat
    20641 gccaactttt attttacata tgatttgcca gagtatgaag tttttgtagt ggtagataaa
    20701 atgagaatgg aacaagtagt agagaatcta attattaatg caaagaagca tgttgtatat
    20761 aatggtaatt tagatttatc gattacatgt gaaaatggct tgattttatt tgaaatttat
    20821 aatgatggta ggattataga gcaagatgag atttcaaaga tttggtctaa gttttatcgt
    20881 agtgttcaat ctcagcgtac aggaggttca ggtctagggc ttgcaattgt ttcacaaata
    20941 cttacaatgc aagggttaga atatggagtg aagaatcgtg atagaggagt agagttttat
    21001 tttatgattc caattgatga ataatttagt attaatttat aaattataag tatttgatgt
    21061 aaaatatttt tctttgtaga caatagatat ctaaagagaa taaaataaaa aaatttaatg
    21121 aaaaaagctt aatgaaaaag tctaataaaa aaatttaata aaaaaattta ataaaaagct
    21181 taatgagaag tcttgttttc ctgatgaaaa caagattttt tattaagctt tttattattt
    21241 caccttgatt tcacaagaga gacactttga tttcaccaaa tagaaataaa ataagttaaa
    21301 taaattaaaa aatagaaacg taattaaata agcttacaag ggggagtact tatgaaatgg
    21361 tatacatggt tgactattat attgatagta ttggtttcta ttccgcttaa aattaaattt
    21421 ataaaatggt gggacagacg acaaaaaaaa tgataaagga ggttatgata gatgataaaa
    21481 gtagaagagt tgaaattttc ttatggaaaa gataaacaga tattacatgg acttaatttt
    21541 gaagtaaaag aaggagaaat atttggattt cttggaccta atggttcagg aaaatccaca
    21601 acacaaaaaa tcttaaatgg tgttttaaaa ggttacaatg gtcacgtatc catttttggt
    21661 aatgaagtta aagcatacac agaatcttta tatcaaaaga ttggtgttct atttgaattt
    21721 ccttatttat ataccaattt aagtgcaatt gataatttag aatatttttc gtctttttat
    21781 cctaaaaatc aaaggagaga catatatgaa ctcttagatt tgttagagtt taagaaagag
    21841 tttataaata agcctgtatc atcctattca aaaggtatga agcaacgtat tagcatggca
    21901 agagcattgg taagtaatcc aaagttgttg tttttagatg agcctactag tggacttgac
    21961 ccatctggag ctgtactatt tcgtaagatt attgaagaag aacgaaaaaa aggaacaact
    22021 atctttttga ctactcataa tatgctagat gcagatttaa tgtgtaacaa tgtggctttt
    22081 attgcagatg gcaagattat ggcaatagat aaacccaaaa atttaaaaat gaaaaatagc
    22141 aataataaag ttgaagtgga atttgtatat aatggaagtc gagatattaa aattgtagat
    22201 ataggagaat tagaatctgg aataactttt aaatatgacg aaatcttaag tgtacattca
    22261 aaagaagcta cactagaaga agtttttatt aaatatacag gaaggatgtt agtgtaatgt
    22321 attctaaatt ttttacctta gtaaaaaagg atttttggat gatgatttat ggtaaatttt
    22381 ttgtactaac acttggctct cttatacttt attcatgtta tattaatttt ggttatgtaa
    22441 agtttatgga tgaagatagt tatcacaata atgtatatct atataatcca gagaatataa
    22501 gcatgagtac atctccatta attaatcaag tttcttctat aggtgaatta aaagcaaaac
    22561 ttgatgaaga tacaagtgca gtttgtattg atatgagctc cagtaagccg aaagtaattt
    22621 tacatgagag tattaaaggc gttgacaatt atagagctga ctatgcattg tcattattat
    22681 catcagaaaa agaccataat agcaaaatat cggacaacaa tgcaataatt caaattaatg
    22741 ataaggatac atctgagata aaacaaagaa aagaaatgac ttgtgagatt ttattctttg
    22801 aaattgtagc tattggattt ttagggattg cctctttatt atttaaagaa aagcagatgg
    22861 gggtaatgcg tattactggt attttacctg taaaaagaag cctttttata ttatcaaaga
    22921 tatttgcttt tttgatatgt gacctatgtt ttacagtgct tttagtagta tttaatgttg
    22981 gattttttga aggaataaaa atactttcac aagtattagt tcaagctagc attttatcaa
    23041 ttattatgtc tttgattgga tttggatgtt caatgttatt gagagatttt aagcaatttt
    23101 ctcttatata tcttgtggtt gctgtattta taactacacc tatatttcta tctgcaaata
    23161 catcttttga aatagattgg attaaatatc atcctttcta ccatgtttat atccagctta
    23221 aaaatgcgtt tttcatgaat ttttcaaatg aattaatcta ttttgtagtg tgttccttga
    23281 caataatagt tctattttta cttgtaaaaa atatttttaa taaagagttg gttagggagg
    23341 gataatcttg ataggattac gttatcagtt gaagagtata agaaaagata aaatgtgtat
    23401 aatttcattc tttttaccag ttgtcatggc gattttaata aattttatgg gaacaattga
    23461 tatgtcttca ttaggagaga tacattttgg tatagtaaag gatacacttc ctgtacgaac
    23521 agagcaatgg ttgaagaagt atggtgtgtt aagtgtatat gacacaaaaa tgcatctaat
    23581 acgtgaaatt aaggatatta aaacggatac aattggagtt gttagagatg gtaaagggat
    23641 aaaaactgtg ctttatggaa atgagattaa tgctataaaa aatgttggaa agacattgcc
    23701 agagatgttt agactaaagg gagatttaaa agatgttgag gttacaatat tgcctaaaga
    23761 tagtatttta aaagagtttc aaaatgtttt tattgctatg attttaatta ctgctatgtt
    23821 tatgggatgc acctttaatg caatgaatat tatatctgaa aaagaagatg gaatatcatt
    23881 tataaatgaa attttaccac agagtagaag tcagtatatt atacaaaaag tatttttggg
    23941 tcttttatgt gggtgtctat cttcaatgat aactgtattt atatgtttgg atatttcaat
    24001 attagatatg ataatgatgt tactactcgt tgtattttca gcatttattt catcacttat
    24061 aggtttattt attggaaagt tgtcagaagg tcttatggta ggaattgttt atattaaaat
    24121 agtaatgatt ttatttatag gtgttccttt gttaatatat cttctagggg ttaatacaag
    24181 cggtataggg aatttatgct atataatgcc gtcagttgct acatttaatg gtattatgga
    24241 gattattaat ggtaatgtca ttattataaa agatattgta attttggctg tacattgtgt
    24301 agtatggttt atgctgtata ttattttaga taaaaaaaga aagttatctt ttagtagata
    24361 actcaatata attataatta gaacaattta ataggtgatt taatatactt tgtatagtgt
    24421 aatttatgta gtacaatttg tatactttaa tttatgtagt gtaatagtta gttttatttt
    24481 ataattattc aatataattt agtaagaagt tcagtacaat tagagctact tagtggaaaa
    24541 tttaataggt acttaaacta tataaatact ttattttcct ccatttgtac tataaattta
    24601 attgatgata taaatggagg tattattata tgatttgata aatttcatca ttataactta
    24661 caagtaaatg tattattata tgagatatta ttatataaag ttaataaaga tagtatcaaa
    24721 atattatttg ttataaagag aggggctcaa aataaagata aacctatttt tcaatgttga
    24781 aatgataaaa acatatttga ttttatataa aaaattttct tcatgaatta aaaagtccat
    24841 tttgagaccc ctcattttta accagataaa tcgagttaaa ctatttaaat atattactcg
    24901 gattcatttg acttagatat tccttgcttg taaaattgtt ttgagtaggg aatagccaaa
    24961 gcaaaaaata aaagtataat ccctgctacg attattaaat tattaataga cattacatct
    25021 gccattgggc cgaaaatcat cataccaaga ggaataaaac cagtatatat aataataggt
    25081 aagctaagaa ctcgacctag catttgtggt gctacatgct cttgcaacat agtcatagct
    25141 gatgcttgaa tgattggaat tgaaaaattc gtaaaaaaca taaatataaa aaattgccac
    25201 gcttgtgtta caagacctag aataattgaa aaaatagcat aagataatat tgctagaaaa
    25261 aaggtcttat ttctattttt aaaaccacca aaaactccta taatcaatcc acctaaaacc
    25321 atacctaaaa atccaatcat ttcaataata gacaggtata tataaccctt gccaaatgtt
    25381 cgttcaataa gaagtcctat aagaaatcct gatggaacac aaagaagcat gaatgctcca
    25441 taagtgaaaa gcacttttct aatgaactta tctgaaaaac agtactttat ccctgatacc
    25501 atatctgcaa aaaatgagac tttttcagtt tgttttggta tatcatgttt aggaattttg
    25561 ataaatatca ataatacaat agcaataatt gcagtaaata catcaattaa aagaacttga
    25621 tttattttat taccaaatcc aaggattgca gcagccacaa taggaactat aaattgtact
    25681 atagactgta ggctaccatt tataccatta aaacgcatta aatgttcttc tggtacaagt
    25741 tgaggaatca ttgcgtttac agcaggtgtt tgtacaccac ttcctagtga acgtataaca
    25801 gatattactg atatggctat taattcactt gttgttccat ttgatgacat cataaataga
    25861 attagaacta atgtagatat agcaattgtt gaatctgata caattatgag tacctttcga
    25921 ttgtagtagt ctgcccatac accagcaaaa aaagaaatta tcatttgagg tataaaggag
    25981 catatagtta aaactgttac ccatacacct gatgatgtct gaagtgtgac ataccatatc
    26041 attgccatct gtacaagtga tgagccaaat aaggaaatat attgacttgc tagaaaaaga
    26101 atgactcttt tcttccatgt agaattaata tttttgtttt ccatcctatt cctcctttga
    26161 tttgtgtgtt taatttttct cgctcttaag gataacacac aaatcaaagt ctggagttag
    26221 agtggagggc taggaaaatt gttttttcat aatttgaaga tgagatttca ttgtttttgc
    26281 attatgttca gcttctttca atgaagttat cagtttgtca cacactgaga taatttcgtc
    26341 atcatctttt ggagtgtcaa ggacagtttt aatattggta ttaggattag aagataaagc
    26401 attgagcatt cgtaaaatag ctgaaagaga atagtttgca caacgaagtg cacttataat
    26461 tttaagtcgt tttatatcct catcagtata tacacgataa ccattttgtt ttctttttac
    26521 ttttaacaaa ccattcattt cccaatttct taaagtatct attgtaacat ttaagtgttc
    26581 tgcagtttct tttctagtta aaaagagttt atctgtttct ggagtatgtc catttaaaat
    26641 ctgtgtaaca atagtaagtg cttcctcggc attagatttt tctatttcta attgtttcaa
    26701 atattgattt acaagacaaa tagccttgtc aaaatctcta tttgctgatg ttcttacaat
    26761 ctcaagggca tcttttctta atcctctttg taccacttca attttcaagg ctgtacgagc
    26821 aaatctaaat tgttctatat gaaaatcatt aaagatacga taaccattgg tattacgctt
    26881 aggtttaggt attaagctta gctcttcata taaacgtact gtattaggat gtacaccaat
    26941 taaatctgct acctctgatg tcgtgtaagt gtccattagt attcaactcc ttttagatat
    27001 atagtattag tcataataac atcaaacaaa agtctggtgt tatagtggag ggtttggtta
    27061 tctaagagta attagtctat ttaagattaa ttactctatt atagaagtaa gtatatactt
    27121 ttcaataaac tcccatctat cacgaggttt aaacactatt ttagatggta tggctattac
    27181 taagtcatat tgtggaatac aacaaatagc atttcctcca gctcccattg ctgaatacca
    27241 caaaactcca tcttttttac atagccacca cagataaccg tattcattac tattcatttt
    27301 aactgattct tcaatccacg atttagatat aatacgttta ttattccaaa taccatcatt
    27361 taaatacaga aaaccaaatc gcaacatatc tctagcactc aatgtaagtc cccagccacc
    27421 tgtagaatag ccctgtctat cttttgccca acccttaaga ttttttccaa agaaatcttc
    27481 aaaaccaaaa tctttcatat cataatctgg tataattttc ataccaatag gtttaaataa
    27541 gtattcatta gcaaattcac gagcagattt tcccgtagtt tttgttataa tagctgaaag
    27601 taggtgtgtt ccagctgaag aatatttgaa agtaccaatt tcaccttttt gaccaagctg
    27661 attcaaggta tattttatcc aatctttttg tttgcaaagt ctctctaaag actcagtcat
    27721 atttttaaaa gggtatggtg cagtcattgt aagtaggtga cgtatagtta ctgctttttt
    27781 acatatttca gaaggactac aagtatattc agggaaaaaa tcaacaacct tttggtcaac
    27841 atcttttata tatcctttat ctattgcaat gcctattaaa gctgatataa tactttttgt
    27901 aactgatgca acatgaaaag tatcgtcagc attatatcca ttgtagtatt tttcaaagac
    27961 aacttttcct tttcttgcaa taattattcc atttatattg ctatattgtg agattattaa
    28021 aggttcaagt tgtgaaagct tttctgaact cataccaaca cttgaagggt ctactttttc
    28081 aaaaattaag tctaagcaat tgtttttatt cattaaagat accttcctgt tatagatttt
    28141 ggattttctt ttagagtttt tggagaacct tctgcaatta tataacctcc tttgtcgcca
    28201 ccttctggac caagttcaac aatccagtca caaacattta atacatctat atcatgttca
    28261 acaacaatta cagaatttcc atttgctact agttcatcca acaattgaat cagcttagca
    28321 gtatcatata gacttagacc agtagttggt tcatctaata cataaagaat attaccattt
    28381 cgttttttac caatttcttt tgcaagcttg actctttggg attccccacc acttaaagtt
    28441 ggtgtaggtt gacctaattt tatatatccc atacctattt gttctaacac atttaagtgt
    28501 gaaacaatat ttggaatatc tttgaaaaaa tttacagcct cagagatact catatttaaa
    28561 atatcatgaa tagttttatt tttatattta atagataagg attcatcatt aaatcttttt
    28621 ccatgacagt cactgcatat atggtctata cttagattat ttcctaacca gactttttca
    28681 tatccgctac cactacattt aggacaagcc cctttggagt taaatgagaa atgaccagct
    28741 gtaaatcctc gctctaacga ttctggctga cctgcaaata gtgtacgtat cttatcccat
    28801 ataccaatat aagaagcagg agttgagttc atattttttc caataggaga ttgagatatt
    28861 tctgaatatc cagaaatata cttagtacca atcaatctat ctgcaatagt ttcgacaact
    28921 gcataatcat cttcatcacc tatttcactc tctgaagaat ttgtttgatt attgatagta
    28981 tggttattaa attgacttct aagaagagga agtaaggtgt ctgatataag tgaactcttt
    29041 ccactacctg atttgccaga tattccaacc atagcaccca aaggtaatga tactgttaca
    29101 tttttaaggt tatttgtatt tgcattttga acagttatac agggtatttc atcaatatgt
    29161 gtaatatttt tagtgcttgt tctattaggc attgaatatt ttccagatag atattgtcca
    29221 gtaagtgatt tattggattg aagtagacct tccaaatttc cttgatatac taattgccca
    29281 ccttcaatac cagcttttgg cccaatatca ataatatgtt ctgccatctc aattgtgttt
    29341 ttatcatgct caactactat aactgtattg cctaaatctt taagtttctt tatggatttt
    29401 aagatgtcta ttttttctga ctcatgcaat ccagcagttg gttcatcaag cacataaatt
    29461 aatgaatcca tctctgaatc aaggtgtgaa tttaaaaata gtctttgcat ttccccacca
    29521 ctcaaagttg atatttctct gtataaggat agatgaccta atcgtgattc tattagatgt
    29581 cgagttttgg acaaaatatt atttacaagg tttgtaccaa atgtgcttaa attaccttgg
    29641 tctaataaga ttttaaggaa ctcatcaatt tctagaatcg tcatttttcc aagttctcca
    29701 atatgttttc cgtttaaaag tactctacgt gcttcttcac caattttaaa accattgcaa
    29761 tctgaacagg cagtcatagt ataaactcca tttaaatctt cgcctctttt gtaacgattg
    29821 tgaaatacct ttgataaaga ggaacttttt ttgccatttt cataatgacc atagagcact
    29881 tcatttttta cttcttcagg taattgtaag aattgtatgt ctaaataatc gttgaatttt
    29941 ttagagaata ctctcaaata tcctggtgta atctttgctc tatctaagac ttgttttagg
    30001 gtatcatgct tatcaaggac taatttttca atattaatct caaaatatgc accatgccca
    30061 gaacatttca tacacattcc atctgaagag ttgtatgaga aataacttgg ctttaatcgt
    30121 tcttcttcat acccacaatt attgcaaatt aaattatcgc ttacaggagt atcacacata
    30181 gtacacatta tttgaccttc tactgaatac aatagtgtaa gcatgttgag aatattggtt
    30241 cttgtgccta ctgttgaacg aggattactt tggcgaataa tattttgttg aacagctata
    30301 gtgggagcta aaccttgaat attatcgaac ttatcctcac tatcaatacc tgcaagtata
    30361 cctaaagatt gaaggtattg tttacgtcct tcctcaaata caatgtcaaa cataaggcta
    30421 gatttacctg agccactgac acctgttgca acaaccagct tatctttggg aatagaaaca
    30481 tctatatttt taagattgtg tatctttgct ccattaattt ttatttcttt cattggttca
    30541 cctcatttta tcaattttat caaaccataa aatagggata tattaatcct taatacaaga
    30601 atagattagg tgaggttatt aaaaaggttc tataggtaaa tatatatcga ccaagtgtct
    30661 attttgaggg tgattgtgtg ggttgttaag atatacttca aaagggaagg aagcacgtag
    30721 cttataatta acatttgata accattcatt atacataaaa tcccacgcat cactatattc
    30781 agattttgaa atatcaaaat gtcctacaag atattttcca gaaggtatta tcatattgcc
    30841 aagattgtca ttctctttga caacaatgtt atctggaatg gtcatgcaaa tactagtcct
    30901 taattgatgt tcctgtgtaa attgtggatt atcatgataa attgctaata tttgtgtgtt
    30961 ttcaagtcca agtagattct gctcacttgc atatgtgaat aacctttcta aaagttttgg
    31021 gaaagtacta gttagattac catatgaacc agtatatcta gtgtaaatag tattcatatt
    31081 atcaagttct agaatttcaa tttcaccttt aacctctcta gtattcttac atttaggttt
    31141 tgatatgctt ctattgtact gagaaatttt atatggttct ttgcaattct tgctataatt
    31201 atttctatat tttataggac ttattttata gtaattttta aatgctctcg agaaaactgc
    31261 tgaatcagta aagccgaagt agtgtgcaat atcagtaatg gtcatgtcag ttcgatgaat
    31321 aagaaaagca gttgcattct ctagttttag cctatttaca tactgtgcca aagtttcttt
    31381 ttctattgct ttgaagattc tatgaaaatg aaactttgaa aaacctgcta tattagaaag
    31441 ttcgtcaagg aaaaggggtt catgtaaatg ttcttctata tagtcttgca ctttgcaaat
    31501 acgatttaga tattcttttt tacttttagc gtttgtcata aatagccctc cttattgtgt
    31561 aaaatgtgta ttaatttata gtaatatagt aataaaattt tatgtttttg taatttatga
    31621 taaataagat agcgttcaat tttttataat taataaaagc tatttataat taataaaaaa
    31681 tgtaagatgc attatatctg tctttgcata taagtataat cttcgtaata attagtatac
    31741 catagtgatt tatttttaat tgtgcattta tataaataca caacttatga tatggaagag
    31801 ttattatgca aataagctgt aattaaataa attacaatat aaactagtta aaacataagc
    31861 cagaaaaata ctatcaaatt tgttacttag cacaagagca tagaggagat aaaataagat
    31921 tgaaaaatta catactaaat ttaataaaat ttttatatta aaaataatat taagtttatt
    31981 gtttaaataa aaaagttaaa tctacactat taacttatta tacttaaaac tttaaaatga
    32041 aaatatcaaa gaatactttt taataaaaat aataatttaa taagttattt ggaaatctaa
    32101 aaactttaca acaaattatc tatttaaatt ggaggagtgg gaatatgagt aatagttttt
    32161 atcaattaaa ttcagcagta ttatatttta atgaaaaaag agatgtaaat agaataaggt
    32221 ttaatcacta tgtaatgaga aaagaaaata tacaaagatt aaaaggaact ctgccaagag
    32281 gacaatttat gatgacagta aggaaagctg catctgacct tgatgtatct acatctacaa
    32341 taagtagact tgtaaatgaa tttatagatt taggtatatt gagattaata agtagaggag
    32401 taaagggaaa ttgttgttct gtatatagtt atgtttgttc tgaaaatagt aatacggaga
    32461 ttttaacagg gaatagtggt attttcaaaa acatagagaa ataccttgat gtaaccatta
    32521 acaataatca aaaaacaatg aaatataaac atagagatga gttgttcaag aatagtaata
    32581 ccaacacata cagccgtata aatgaagaac atatagataa aggttatgat tcgataattc
    32641 atactgggta tgaaacagaa aacgagacaa agaaaaaaga attattaaaa aataatttaa
    32701 ataaaaagaa tttaaataaa aatacctttg aaaattcgga tgaagatttg aattatgaaa
    32761 gtccagaaag tatacatgaa attattataa gaaaattaaa tagtgaatcg ggaaaaaatt
    32821 ttaaagctga tttaagtata actaaggcac ttatagataa aagattaaaa gaagggtata
    32881 gtttagaaga tttttacaag gttatagagg caaaggtaag aagatggaga tatacagata
    32941 tggaaatata tatagaacca acaattctgt ttgggtatga atttgagtcg tatttaagtg
    33001 aggagagttc tttatctgct tgtaattatg gtgatatgtg ttatgaggat atgtattgag
    33061 atatttatta agatattagt tgctttttag ttgtttaaaa tatgcttata tataagtata
    33121 actagtgtat taaaaatgga attgtctcaa aatagggaga agcctctttt taattgttta
    33181 aatgatgaaa atatatttga tttaatacaa aggagagtgc ctcatgagct agaaagctca
    33241 ttttgagaca cccacttttt ttaatatact ggagaaatat aacccatttg aatggctttt
    33301 gtaatagcct caactgatga tgaaacatct agcttgtcat atatgtgttg taaatgattt
    33361 gataatgttc tttcacttat atacaattca tcagcaatta tttttctttt tttaccacta
    33421 cagataagct gtaaaattct tttctccata ctagttaaat cttcaataat tacttcagta
    33481 ttttcagatg gaaaacaagt tcccccttga tagactttta ataatgaatc aattaaacta
    33541 tcagggctaa tattcttatt taggaatcca tagataccta tttttttagc ctcatgttta
    33601 taaactggga ggtcgtatcc agtcaagatt attattttaa tagttgaatt agtttctaat
    33661 aaattataag ctacttttaa gccatcacat tcacttaagc ctctaaggtt tatatccatt
    33721 aagacaatgt ctattttttt atcttgaatc atttctgata gactatggat gtcctgtgtg
    33781 gaataaaact gttcgatttc ttcgtattct tctagtgcaa tggacaagct tttagaaaaa
    33841 agcatatggt catcaactaa caaaatattt ataagaaaca tctcctttca tagggattgt
    33901 aatctgtaca caaactccat gaggtatatt atcagaaata cttatcgttc ctcctagatt
    33961 ttctacttgt tctttaattg agataatccc tttgtgtttt attgtatcaa aagtaatttt
    34021 agttatatct aaaggcgttt taaaagatgt atttttcaca ccattatcat taatatttaa
    34081 tttaattata tttttttcta gtgctaaagc tatccatgca tggctaccat ttgaatgttt
    34141 atatacgttt gtcaataatt ctttaattag tcgatatatc aatatatcat atggttcaac
    34201 taagaataaa gtatcagaac acttaaatga aacacaaatg tttttttgtg gaaaggatga
    34261 agaaacactt tcaattaaat tctgataatt ttcttttact gttaaatttt ttaaaataac
    34321 agggtgatag tcttgcattt gttttcttat acatgtattt agattgttaa gtgtttcata
    34381 tataatatct tgaacttctg ggcgatatga cttactcatc atgtttttta ttgaaagcag
    34441 gttttgtaat atatcatcat gtaaaaaatt agaaaactct gtttttagtt gttcttcttg
    34501 ttgtaatttt tccaatgcaa aagtatactt gctattttta actactttat ttttttcatc
    34561 tctaagatta aactccaaaa taatgttaca gaggaaaata agcataaata aaacatttat
    34621 agctattaat attatagaaa aattcccact ggcaaatagt acaaccaagc taattactaa
    34681 tatacttata aaaagaaata tagacctttg ctttatgtta aaaactgttg aaataggaaa
    34741 actatcattt tctttaagtg caataccatg aatactcata aaaaatacta atacagttag
    34801 atagattcca aaattaccaa tatgatttga tattcttagt gtaaaaaaat aataagtaag
    34861 gaatcctata attgttataa ataccgaaat cgatataggt tttttttcac tttttatgac
    34921 aaaagcgacc cttttccaat gataaaaaat aatatagaaa aagcttatta tactaacaac
    34981 aaactgtatt ccgtacatac aagcatacgt tctgttagaa ataaatgctc ctacaattgc
    35041 accaatgcag gtgataagca ataaaatgtc tgttatctta cggaacttgt atccactacc
    35101 ttgaaacaaa aataaaaaaa taaatttaat agagacatac gctataactg tgcttaatat
    35161 tttaaaaata atagtgccta ttggtgtggc tacaaatgat aagagtaaat accaactgtc
    35221 tagtactagt aatccacaaa acaatgaaat aatgttattt tctcggacat tacaagaggt
    35281 tatatatgtg atgtctatga gtaataatgt tgaaattatt aagggaataa tgctttggat
    35341 attcatataa gttttagtgc ttgtagatat tcccatgaag agaagtgata gaatgtagtt
    35401 tcctaaaaat agtattttta aattaaaatt tgtcaatctt atacacctcc ttatgagtta
    35461 attatattaa ttttatgact aaatcaaact taagaattaa taactttgaa ttatattaat
    35521 tttatgactg tatcaaattt aagaattagt aactttgaat tatatcaatt ttataaatat
    35581 atcaaaccta agaatctata gttttaaatt atatcaattt tatgattgaa tcaaacttag
    35641 gaatctatag ttttaaatta tatcaatttt ataaatatat caaacttaag aatttataat
    35701 tttaaattat atcaaatact tataaatgaa gtataccaaa tcgtcacacc tttaagcttg
    35761 acgatttggt aaatattatt tttttagtac aattttacaa caggatttaa tagtaaatat
    35821 ataatatatc aaatacacta cagaagttaa gaaaattgca ataatcacag gtatgtattg
    35881 tgaaagtgaa tttccaagta aattctgcat caaagcagtt ttataaacca aggtagcaaa
    35941 tatacaatcc actataccaa gtaaaaacgg aatattaaaa aatggcaata cttgtttttt
    36001 aataattttt ttaatttgta tattagtata acccattttc tgtaaaattt tataatcaga
    36061 tgttgaatct gaaattgctg atatattgtt aaagtataaa atacttccag aagcaataaa
    36121 gaataatact acaagaaatc cgattaatag aaatgtagaa ctattaattg ataataaatc
    36181 atttatcctg tgagaatatc cttgtaaata agggcttcca tctaaataat ctgaaatatt
    36241 actatataaa ttttcattat ttttaattga tttaccatta atacttaaaa tgcttgtcat
    36301 tgggaattta ctttgtgcta tttgctcata tatactatca ttaacgataa gtgttccaac
    36361 gctattagca aaagaaatag cattgtttaa tgatgtttcc cttacagtta caggtgtttc
    36421 tttaccatta ataagtaata gataaatcgt tccattttca ctatatccat cattgtttgg
    36481 ttgatatttc attaaaatac attcattatc ccttaaaggg gtaagttgtt ttattagctt
    36541 tgttcgattt tgtgccttta acaaagtata ataatcagaa aaagatatac attcaaatcc
    36601 tgattctctt gaaataactt ctttagaaga actactatta gataaattat tcttagatgc
    36661 accaatttca tattcaaatg gaaggtcttt tgatgaagat tttaccttat aaatatttgt
    36721 ctgtgtaaaa ataatatcgt ctgtattaga catgtattga ctgacaattt gttttacatc
    36781 ttctatttgt ttattttttt ctactctaaa ttctatctct gaaggtgcaa tacgtgaaac
    36841 ggatgcaata gggtagtata aagacagtgc catgacactt gaaactgtca aagtagcagc
    36901 agagagtaat gtaagcataa ttagagtttt agagtttgaa cggatacgat agataaagtt
    36961 tggaatagtt attatctttg tacctgtata gaaagctcgt ttattttttt tactcttttg
    37021 cataatatat ggaagaaagg aattgataaa gagaactgta ccaattacaa tgataatcat
    37081 agttatcaag cctatttgat aaaatccaat acttatccat actgacttag ctccacgaag
    37141 aatatctagt gataaacaat acccacttaa aatcataata aaccccataa aggctggaat
    37201 ttttctgaac ttcaattttt tttctgtgct tttttcatat cgtatcaatt ttataagtga
    37261 agtcttataa agaaatttac catttgatat agctaagact aaaacaacta atgctataaa
    37321 gataattgtt ttgtttattg catttatatt aaaaaatggt atctgtgaat tatcaattga
    37381 taaattaagt agtgctgtaa ttccaaagac aatactctta tgtaccaatg ctcctaatac
    37441 caatccaata ataaaagctc cactacaagt taatatattt tcaaaggtaa gtagcgataa
    37501 gattgtaaac ttacgatatc caagtaaagc atatatgcct aattcctttg tacgacgcct
    37561 taagaagaat cgatttgagt atgccatata gaagatgaca aatgccatca aaaatatcga
    37621 aataacatta cacatagatt caactctacc atcagttgaa attttttcta gcattacctt
    37681 attaacagaa aatgaagtaa atgcgaaaaa tacagtaata acaaaagaga ctgaaagtag
    37741 atatagagaa tagaatgaaa agtttttttt aagattcttt attgccatat aaaaaatgtt
    37801 cattaaatta tcctcctatc ttttagtatc caattttgca atttcttgaa taatcaactc
    37861 ataaaatgta tgtctattat tctgttgttt atttaattct ttaatgatat gaccatcttt
    37921 aaaaattaaa attctatttg caaaacttgc tgcataggca tcatgtgtta ccattaaaat
    37981 tgtcgttttc aactctttat ttgcttcttg tagtgagtgg agtagttcag tagctgaatt
    38041 agaatccaaa gctcctgttg gttcatctgc aaagagaata ctaggctgtt ttactattgc
    38101 tctaactgct gaagttctct gtctttgccc accagataat tcatttgggt atttgtttaa
    38161 ttgagaagct atgccaaatc gttcagctag actctttacc attttttcta ttttatctgg
    38221 acttagtttt tgaagtgtaa gaggtactga aatattttcg aaagttgtaa gactatctag
    38281 taaaaaatac tcttgaaaga taaagcctaa attatcctta cgaaaatcag cagcattagt
    38341 gtcattaagc gatttcaaat ttatattatt tatgaaaatg tctccacttg ttggtttatc
    38401 aattgtagat aatacattaa gaagagttgt tttcccagaa ccagaagctc ccattatacc
    38461 tataaactca ccttctgata cattaaagga taccttatct aaactcggct gttgtccttt
    38521 ataagtttta gttatgctat ttacttttaa tattgtattc attgtatatg cccctttcat
    38581 cttgatatag tcaaattata tattaacctt attattcaat catgagtaaa tcacgcaata
    38641 attctacaca aattacttat atcataatat attgtttaaa atctaacttt attaggtttg
    38701 ggatgatgga caagatttta atttaaaaga gtgcatagat atataatggc ataatgtgga
    38761 tttaaattaa aaaaataaag ccataaatat tgaaaaattc aatatttatg gctttattgc
    38821 tttgtaataa ttaatagaat atatattttt tattaatcat ctatttcaaa ttctaatatt
    38881 ttaccagtaa ttgcattaat tgttatctca tattcagttt ttccttttat tatttcacct
    38941 ttatattctt tgtcatcttc atcatattta aattttacta ttttcccacc aggcacttta
    39001 tctagtatta ttgatttagc tttttcagca ctaataatag aactgttgtc attagtatta
    39061 gagttattat tgtgattatt atcattatca tcaatgtcat catcagaatc attgtccata
    39121 tcaatatcta taattcttcc atcaaatgca cttatctcta attcatatgt tttcttattt
    39181 tttattactt tagcttcata ttcattatct tccgcatcat atttacaata gattaaatta
    39241 ccattaggaa cagcatctag tgctatagcc ttagctttat ccaatgatat attttttgta
    39301 cctaaattat tatcatttaa gtcatcatct ttttcaattt ctattatttt accagagtag
    39361 gcatcaattt ctatctcata tagaacatta tcctttacaa ctttgcagtc atattcatta
    39421 tcatcttcat catagtaaca aactaaaata tcacttcctg gaagagtttg ttttaatatt
    39481 tctttagctt gtattaaaga tattttttta gttttatttc ttatgttcac attctttagt
    39541 tttaaaatat cttcaaacgc tttttgatta tatcctcctc ctacttgtgt tatttcatct
    39601 atatctttat tttcaataaa ttccttttga ctatttacaa ggctaccatt agatatcatt
    39661 ataggagaat tttctttagc agctagtact cctattgata atgaatctac tagtgcattt
    39721 tcttggctaa taccatcttt agctacaaag acattattta tttttttatc tttataaaat
    39781 ttatctataa tttttgcatt agtattgttt ctatctgaac cactaattct ttctctgttt
    39841 ggatatttct ttactgcatt atcagataaa atcttatttc ctccaactat gtaagatttt
    39901 tttatagacc tactgtttaa gaaatttacg ctactatcat tgctgttttc atctgatact
    39961 aatattatag gcatattatg tattgctgct ggagaagcta tactaactgc atcagataat
    40021 ccctttagac catttacaac tgcaacattt tctacctttt ttatcttatc tatttcttta
    40081 agtacatttg tagacatttc atagatattg tttcctacta ttttatttat ttttatgtta
    40141 agcgccttta tttcattttc tactttagaa gaaatactat ttccactatc tacaatgtac
    40201 acattgtcta caccaagcct tttaagttca gctttagttg aactttctat gctattgttg
    40261 tttactaaaa gtataggtgc attctttagc ttagcaaatg gatttgcaca aagagcactt
    40321 tgaatagagt taccattaac tataatggct gtttttgatt gaacccatcc taacttactt
    40381 acttctacag ctgtctcata tcttgtttta cctattaatc tttcttgctt tgtagtattg
    40441 tctgcaaaaa tcgatgaaga gctagaaaaa aacataatac ccgatattaa tatagctaaa
    40501 tttttcttat tcatattttt acctcacaat ctttaaaaat tttttattta gcatacttaa
    40561 taaaatataa ttttaaaatc aaattgatac tgaatttgat tttagaaaat aaacaaataa
    40621 aatttctttg atacaaaatt ttccttttat atttaacatt gtatcacaaa tataaagagg
    40681 aaaaaacttt ttaaaaagag tatacactat tcatttttat catcttataa ataaatcttt
    40741 accactgttt tatatgtttt aaaatagaca caaaacttat ttctaaattt actacaaata
    40801 ttttaggtga aatttctttt taagcatatc taaaaaatat ttgtagtaat gctaagggat
    40861 tggatttctt aaagtatata tttctttgga tgtttgagtt tgtgaaattt gagaattgga
    40921 gggtgaaagg aacactcaat ggattaatat taaaaactac atttgtacaa taattgcctt
    40981 aaaactaaaa aaatctattg acttgaagtt aactccaagt agtaaagtat aattatacag
    41041 gaattatata cttgtaagaa tacttaaagt agagagataa aacaaataag ttttaaaggg
    41101 ggaagtaaaa caatggagac aaaaaaatta ggatttggat taatgcgttt accaataaaa
    41161 gatgaaaatg atgttacaac tattgatatg gaacatttga ataaaatggt agacactttt
    41221 ttagaaaggg gatttacata ttttgataca gcttatgtgt atcacatggg aaaaagtgag
    41281 atagcactta gagaatctct agtaaagaga cacaaaagag agagttttac tgtagctaca
    41341 aaacttccat taatggcttt aaagaaaaaa gaagagcaag aaaccatttt taatgagcaa
    41401 ttagaaaaat gtggtgtaga ctattttgat tactatcttt tacacaatat aggtgtgtca
    41461 cattatgaag tagccaaaaa atttgattaa aaaatagcta cgcacactcg tgactttagt
    41521 catgagttag tagctaaatt agtcagcata tagggaaacc tatatgtaga gataggatag
    41581 aacctatcca atactacttg aattgcta
//
LOCUS       DAMKOJ010000030        41513 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.032, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000030 DAMKOJ010000000
VERSION     DAMKOJ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41513
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.032"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(35..610)
                     /locus_tag="PC592_001714"
     CDS             complement(35..610)
                     /locus_tag="PC592_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HDF4055690.1"
                     /translation="MQKITWEVEYTSQLPVIRYCKKCGKKTEYVCSGLFRVNAQHKYL
                     DIWLIYKCLNCDSTWNSTIYSRVNPNNLSPEVLEQFHTNDDNLANQYAMNIELLHRNG
                     AEVGIPEYKIVGQEIDINDLTQIRIVSKYPSQLKVSTLLREKLGLSRKVFDEMLDCGT
                     IKSVSGVDLRRSKLNYEIVLEVGKEKQKSSN"
     gene            complement(905..1183)
                     /locus_tag="PC592_001715"
     CDS             complement(905..1183)
                     /locus_tag="PC592_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055691.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSNTS
                     TREELAIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            complement(1488..2249)
                     /locus_tag="PC592_001716"
     CDS             complement(1488..2249)
                     /locus_tag="PC592_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF4055692.1"
                     /translation="MKNKIETLMNNFVKDYHKFNSITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLKNGKTIITYFIPFDESINNSNIGGFECSEIWARAYIETNMLIS
                     NLNSYLCEELEKIGFDSYAIPGSYNFDSEKLVSDWSQRHVAFISGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDRFDRNKCY
                     EMCTINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(2418..4466)
                     /locus_tag="PC592_001717"
     CDS             complement(2418..4466)
                     /locus_tag="PC592_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore surface glycoprotein BclB"
                     /protein_id="HDF4055693.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNSGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGGTGRGGPT
                     GPTGPTGPTGPTGPIGFGITGPTGATGATGATGADGVTGPTGPTGATGANGITGPTGA
                     TGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGVTGPTGAVGATGIGITGPT
                     GPTGATGADGATGATGPTGATGTTGADGVTGPTGATGATGFGVTGPTGPTGATGVGVT
                     GATGLIGPTGPTGATGLIGPTGVTGATGADGVTGPTGPTGATGADGATGVTGPTGATG
                     ATGADGLVGPTGATGATGADGVTGPTGATGATGVGVTGATGATGATGPTGADGLVGPT
                     GATGNTGADGVAGPTGATGATGNTGADGATGPTGATGNTGADGATGPTGPTGATGVAG
                     VTGATGPTGATGATGADGATGPTGATGATGADGLVGPTGATGATGITGATGVTGPTGP
                     TGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGVSIVGGVIDLTNAAGTLTN
                     FAFSMPRAGTITSISAYFSTTAALSIVGSTITITATLYQSTAPNNSFTAVPGATVTLA
                     PPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVEGYASAGISIN
                     "
     gene            complement(4533..5609)
                     /locus_tag="PC592_001718"
     CDS             complement(4533..5609)
                     /locus_tag="PC592_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4055694.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGSPTLSYYRERLFKRSSNHKWVDPIHEVVPLSGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKVLEPRHQFYYSRELYYNAKYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPYIQLSVCYDRLGESNKAIYYHEK
                     TKEIKPNDSAVLHNENYFNKFKNS"
     gene            complement(5912..6496)
                     /gene="clpP"
                     /locus_tag="PC592_001719"
     CDS             complement(5912..6496)
                     /gene="clpP"
                     /locus_tag="PC592_001719"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF4055695.1"
                     /translation="MSLVPHVIEQTSQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSVTAGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRYALPNAEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDRIFSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(6493..6951)
                     /locus_tag="PC592_001720"
     CDS             complement(6493..6951)
                     /locus_tag="PC592_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055696.1"
                     /translation="MEIIDYIEENLTENLNLDKIADIANYSKYHLHRMFTNIVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITAGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKYISYANMNCKQRIDEINSYLNFNINCEVKVA"
     gene            complement(7174..8589)
                     /locus_tag="PC592_001721"
     CDS             complement(7174..8589)
                     /locus_tag="PC592_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF4055697.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILNGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNYIFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRAEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGVKVDDKGINTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKYATENGYYII
                     EDDYDSEFRYEGQPISSLYELNPNKVIYIGSFSKILSPAIRVGFILLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIEKILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHINQGT"
     gene            8704..9372
                     /locus_tag="PC592_001722"
     CDS             8704..9372
                     /locus_tag="PC592_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055698.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLILKNSTIKN
                     IIEKHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKIELPLKIDLANGSEHFYGIGAKEQILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKYYISSAFPDLKINS
                     IDIF"
     gene            complement(9563..10081)
                     /locus_tag="PC592_001723"
     CDS             complement(9563..10081)
                     /locus_tag="PC592_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4055699.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLDKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGLNKLSKAANIYDAPLAILVCGDKEKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKVADSPDRHEKTR
                     VPLSEIVSYEIL"
     gene            10233..10556
                     /locus_tag="PC592_001724"
     CDS             10233..10556
                     /locus_tag="PC592_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055700.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLEKL"
     gene            complement(10561..10887)
                     /locus_tag="PC592_001725"
     CDS             complement(10561..10887)
                     /locus_tag="PC592_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF4055701.1"
                     /translation="MSSYLNLIREFNLKEKIIAFICVSALLIGKSCVLKNRKATTYHL
                     KNSKRQRQLSEFDVNVVNEPTVVNQNIITSYYTETAPHVAFKLLEMLISKKQLDEVKL
                     AMGFKL"
     gene            complement(10875..11161)
                     /locus_tag="PC592_001726"
                     /pseudo
     CDS             complement(10875..11161)
                     /locus_tag="PC592_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            12169..13707
                     /locus_tag="PC592_001727"
     CDS             12169..13707
                     /locus_tag="PC592_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF4055702.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVIPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQESAISGNEQHLIKASDYQEQLIANNFYSIDNEVNKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHEVLLLDEPTNFLDKEHVEWLSNYLNTFSGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKLHLREDYIRRYQSQQKKIEKEEAFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPGFTGKPNIKFSEIEISAQNALTVTNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPCISGDFQFSEQVKLAYYEQDL
                     KWENPTKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLFPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(13984..14697)
                     /locus_tag="PC592_001728"
     CDS             complement(13984..14697)
                     /locus_tag="PC592_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055703.1"
                     /translation="MDTYFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIVFRVKAQLRRQQYQSIVPSDSSVIKIGDITIDIEGNRVYKDRKEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(15147..16526)
                     /locus_tag="PC592_001729"
     CDS             complement(15147..16526)
                     /locus_tag="PC592_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4055704.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCHSYIFIILIFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGVLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLISEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNMLNINGIWLAVPSAEILTLFLTVFCIC
                     KHKNRYKYM"
     gene            complement(16809..17603)
                     /locus_tag="PC592_001730"
     CDS             complement(16809..17603)
                     /locus_tag="PC592_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF4055705.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPIDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVIIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFSFTLFMWRFWKLGLRHYKSASS"
     gene            complement(17600..18463)
                     /locus_tag="PC592_001731"
     CDS             complement(17600..18463)
                     /locus_tag="PC592_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF4055706.1"
                     /translation="MSIMSNYNEASSNSSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMMFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLSGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKINFAFT
                     SNPIQILISIFMIFLGLIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVKVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            complement(18441..19436)
                     /locus_tag="PC592_001732"
     CDS             complement(18441..19436)
                     /locus_tag="PC592_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4055707.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFIGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAIV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSEYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAVAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEELFNHFQKYKKITVSFSNETNIVFSKDCKVVEQT
                     NHKTSVVVPKERGNETIKWIFDRYDVKDVMIEEEDIVNIVERIYKKGSDEYYEQL"
     gene            20139..21095
                     /locus_tag="PC592_001733"
     CDS             20139..21095
                     /locus_tag="PC592_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4055708.1"
                     /translation="MKNNTTQKRLRDLSKKIWNIYILNPEEEGIKFIISLLDDNLTLI
                     GTGKHEFYETLEEFIIGLEKDQVESNQIDFEIIDEWYSCTKVTDETFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVKDDIIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHI
                     RGDEILIHFSNILTKVFISDAIIGRLGGDEFAVFEYSNQSKEDVENKAKKVLELCLEN
                     NSCSIGISRLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(21674..22372)
                     /locus_tag="PC592_001734"
     CDS             complement(21674..22372)
                     /locus_tag="PC592_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055709.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESIVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKDRQEVYTKKINEAIKNLYKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLYENSTYLNTSDEKESLITKEFNEKVEEEMLNDEKLEELEQKKDYKEDSNKK
                     EKISEDLSLAGKTREELENMLKNFTNLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLL"
     gene            complement(22915..23982)
                     /gene="rsgA"
                     /locus_tag="PC592_001735"
     CDS             complement(22915..23982)
                     /gene="rsgA"
                     /locus_tag="PC592_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF4055710.1"
                     /translation="MNGMKEIDLQDYGLNSNFITQSMKYHDLYIARIISQEKNLYQAV
                     CTGGIVFAEVSGKLRFEATIPSDFPTVGDFVILDRCNDKNGNAIIHHVLHRKSLFVRK
                     AAGKANEEQVVAANIDIVFLCMSLNKDFNTHRLERYLSLTWESGAVPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSAKESDGCQQISKYIKPGYTIALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIADDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGVDKS
                     FADIEAYFGKCHFRNCSHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
     gene            complement(23979..24380)
                     /locus_tag="PC592_001736"
     CDS             complement(23979..24380)
                     /locus_tag="PC592_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF4055711.1"
                     /translation="MNYKNRKRAYYQENSCLDNFICKNCGCIVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNP
                     VKLMSIALKPLAQPPFPLERITEKMEKEETE"
     regulatory      25174..25270
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            25323..25499
                     /locus_tag="PC592_001737"
     CDS             25323..25499
                     /locus_tag="PC592_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055712.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            25909..26046
                     /locus_tag="PC592_001738"
     CDS             25909..26046
                     /locus_tag="PC592_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055713.1"
                     /translation="MSNQREDFDTTNDMFQESIPITTKIILDDIPSHDELNHVFSKGC
                     E"
     gene            26050..26547
                     /locus_tag="PC592_001739"
     CDS             26050..26547
                     /locus_tag="PC592_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055714.1"
                     /translation="MKKRKIVLITLLLIGVLLLGGILYNLFLVKTANISMLKESWNLD
                     IPIPNKEIEVFDTQDSINGDGQSYFIQEFSEKNFKKVFNLKGGIVVSKDNINEIEKYI
                     DKFKRDSVNINKSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYS
                     LIWNQ"
     gene            complement(27024..28382)
                     /gene="rlmD"
                     /locus_tag="PC592_001740"
     CDS             complement(27024..28382)
                     /gene="rlmD"
                     /locus_tag="PC592_001740"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF4055715.1"
                     /translation="MLSKNEVYIVDIVDIGQGGVGVGKYNGITVFVEGGLIQDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGVPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGKENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYADLNETDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNMHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMSPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(28557..30317)
                     /gene="pyk"
                     /locus_tag="PC592_001741"
     CDS             complement(28557..30317)
                     /gene="pyk"
                     /locus_tag="PC592_001741"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDF4055716.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIICVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRVIKNGDTCVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(30369..31328)
                     /gene="pfkA"
                     /locus_tag="PC592_001742"
     CDS             complement(30369..31328)
                     /gene="pfkA"
                     /locus_tag="PC592_001742"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF4055717.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFVGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(31537..35106)
                     /locus_tag="PC592_001743"
     CDS             complement(31537..35106)
                     /locus_tag="PC592_001743"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDF4055718.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     FDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSDEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKIAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFLE
                     LEDLYGAIEIVVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFVDRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(35251..36204)
                     /gene="whiA"
                     /locus_tag="PC592_001744"
     CDS             complement(35251..36204)
                     /gene="whiA"
                     /locus_tag="PC592_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDF4055719.1"
                     /translation="MSFSTETKNELARVVSGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILENKEGFFTINKISDNLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKSSQ"
     gene            complement(36221..36646)
                     /locus_tag="PC592_001745"
     CDS             complement(36221..36646)
                     /locus_tag="PC592_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF4055720.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(36715..37821)
                     /locus_tag="PC592_001746"
     CDS             complement(36715..37821)
                     /locus_tag="PC592_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDF4055721.1"
                     /translation="MAKLLIIVGILGWIALIISLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDKNLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(37833..38690)
                     /gene="rapZ"
                     /locus_tag="PC592_001747"
     CDS             complement(37833..38690)
                     /gene="rapZ"
                     /locus_tag="PC592_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDF4055722.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(38721..39434)
                     /locus_tag="PC592_001748"
     CDS             complement(38721..39434)
                     /locus_tag="PC592_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF4055723.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYNDINILLGMECNILDDKGNIDMDDKFIRYFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVANAISNNDIFIITHPGDKGDV
                     YIEEIAKTAKKTDTRLEINSSHSFLNLNQLNEIKGLENKFIIGSDAHCPERVGDFELA
                     IKTISDSNLDISLVENIII"
     gene            complement(39438..40352)
                     /gene="murB"
                     /locus_tag="PC592_001749"
     CDS             complement(39438..40352)
                     /gene="murB"
                     /locus_tag="PC592_001749"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDF4055724.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRVMDM
                     EGNIFELSNKQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(40625..41395)
                     /locus_tag="PC592_001750"
     CDS             complement(40625..41395)
                     /locus_tag="PC592_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF4055725.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMSTASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSMVVGGIYYLCYVKNS"
BASE COUNT        13705 a         7259 c         4824 g        15725 t
ORIGIN      
        1 actaaagtca cgagtatgcg tagctatttt ttaatcaatt tgaagacttt tgcttctcct
       61 tgcctacctc taacacaatt tcataattta atttacttct ccttaaatca actccagata
      121 cacttttaat agtcccacaa tctaacattt catcaaatac tttcctagat aaacctaatt
      181 tttcacgtaa taatgttgat acctttaatt gagatggata cttacttaca atacgaattt
      241 gtgtaaggtc attaatatca atttcttgtc ctactatttt atattctgga ataccaacct
      301 ctgctccatt tctatgtaaa agttctatat tcatagcata ttgattagcg agattatcat
      361 catttgtatg gaattgttct agtacttctg gacttaaatt atttggattg acacgagaat
      421 atatagttga gttccatgtt gagtcacagt ttaaacactt atatattagc catatatcca
      481 aatatttatg ttgagcatta actctaaata aacctgaaca tacatattca gtcttttttc
      541 cacatttttt acaataccta attactggta attgagaggt gtactccacc tcccaagtaa
      601 ttttttgcat aaatataatt tcctttctat aaagttacta aactaataga aagttatgaa
      661 aaggtggaat ataatcaagt atttttttca aaacaagacc tcctagtttt tgataaattt
      721 taatttcata catataaaaa gctattatct cttatatatg cactttacaa ctctattgct
      781 tatctgttgt ataagttatt gaaattactt aaattataac atctacttat aggaaactat
      841 acctcaaaca cttttatcaa aagaaaatga gccagtataa ttataaaact atactggctc
      901 atccttagat atcttttctt ttttcttgta atacaattct ttggatactt ttcaaagata
      961 aataatactt ttccgataaa tattgcaaat catatccaac ttgatagtct tcgtaaatct
     1021 gcatatttct aattgctaac tcttcacgag tagaagtatt gcttccccat tcttttttat
     1081 tattagattt tctaggaata tagatatatt caccatctac atattcctgt atcagttcaa
     1141 gtaattcttc tggtaatata tgtattgcct ttttatagct cattttgctc tcctattaaa
     1201 tagtaatttt ttattaggaa tagcaaaggg ctatttatat attaaatttt atagttgcaa
     1261 tagcccttgc tatgcaaaaa taaagattaa atcaaacata aagtctcaac cctccttata
     1321 tatcacagcg atacatataa gtctatcaac agtataaata attgtcaatc aatataaatt
     1381 ggttatctaa cttttaaatt atattttatt taattttata tttattttga tagctaaagt
     1441 tttttcatta taaattatat ttaaaattat taataaacat aaatccatta tcttgatggg
     1501 tttattactg aacaaggaac tccaactata cactttccac aaatatcaca tccacctata
     1561 taagtgtact tcttttcatt tatcgtacac atttcataac acttatttct atcaaatcta
     1621 tcttctttta aagcttcttt tacacattta ttaacacatt ttttgcaact attattatgt
     1681 ttatataaac aatattcatt ttctggtctt ttagttggct ctaattctaa acttgtgatt
     1741 atacttccta tccttccaca acatcctttt tctgtaataa gcatattgtt taaaccaaaa
     1801 gttccaagac ctgatatgaa tgctacgtgt ctttgtgacc aatcactgac caacttttca
     1861 ctatcaaaat tatatgaccc aggaatagca tatgaatcaa atcctatttt ctctagttct
     1921 tcacataaat aactatttaa attcgaaatc aacatattag tttctatata cgctcttgcc
     1981 catatttcag aacattcaaa tcctccaata ttactattgt ttatactttc atcaaaaggt
     2041 ataaaatatg taattatagt ttttccattt ttcagaaaat cttttggcat agcatgagat
     2101 gttccaacaa cactttttaa cttctgaaac atatcatcct cggcagatgc ataagcaaac
     2161 aaaagctctt gccactttgt agttatacta ttaaatttat gataatcttt tacaaagttg
     2221 ttcattaatg tttcaatctt gtttttcaca gtatcccccc tagataattc tctatttcta
     2281 atttaacgtt tttattttat attatataac aatactctat attacgctca ctaattaata
     2341 ttaaaactat gtttatcaat cagtcttaaa aagcctctaa tatcaataag atactagaag
     2401 ccttttaatt atttaatcta atttattgaa attcctgcac ttgcatatcc ttctacagta
     2461 ttaactaatg aaagacctga agctgttgca gtaaatacta gtaagaatcg agtttctgct
     2521 gttgctgcta tatttaatcc tgttacaatt ccactagaaa ttgaaccaac tgataatatt
     2581 cctgtaagtg gtggagctag tgtaactgtc gctcctggta cagctgtaaa tgagttattt
     2641 ggtgcagtag attggtaaag tgttgctgta attgtaattg ttgaaccaac aattgaaagt
     2701 gctgctgttg tgctgaagta tgctgaaata gatgttattg ttccagctct tggcattgaa
     2761 aatgcaaagt tagtcaatgt tcctgctgcg tttgtaagat ctattactcc accaactata
     2821 cttacccctg gagctgaact accaaaacca acaaatcctg gtgtacctac taatcctcca
     2881 gctatagttg taagtgatag tggtatacct gatgcaaaag gtattattgc actagcacct
     2941 gttggacctg ttgggcctgt tactccagtt gctcctgtta ttcctgttgc tcctgttgcc
     3001 cctgttggac ctactaatcc atctgctcct gttgcccctg ttgctcctgt tgggcctgtt
     3061 gccccatctg ctcctgttgc ccctgttgct cctgttgggc ctgttgcccc agttactcct
     3121 gctactccgg ttgcccctgt tggacctgtt gggcctgttg ctccatctgc tccggtattt
     3181 cctgttgctc ctgttggacc tgttgctcca tctgctccag tatttcctgt tgctcctgtt
     3241 gctcctgttg gacctgctac tccatctgct ccggtatttc ctgttgctcc ggttggacct
     3301 actaatccat ctgctccggt tgggccagtt gctccagttg cccctgttgc tcctgttact
     3361 cctactccgg ttgctccggt tgcccctgtt gggcctgtta ctccatctgc tccagttgct
     3421 ccggttgccc ctgttggacc tactaatcca tctgctccgg ttgcccctgt tgcacctgtt
     3481 ggacctgtta ctccggttgc tccatctgct ccggttgctc cggttggacc tgttgggcct
     3541 gttactccat ctgctccagt tgcccctgtt actcctgttg gacctattaa ccctgttgct
     3601 ccggttgggc ctgttggacc tattaaccct gttgctcctg ttactcctac tcctgttgct
     3661 ccggttgggc cggttggacc tgtcactcca aatcctgttg ctccagttgc acctgttgga
     3721 cctgttactc catctgctcc ggttgtccct gttgctcctg ttgggcccgt tgcccctgtt
     3781 gctccatctg ctccggttgc tccggttgga cctgttggac ctgttattcc tattcctgtt
     3841 gctcctactg cccctgttgg acctgttact ccaggtgttc ctgttgctcc ggttgggcct
     3901 attaatcctg ttgctcctgt tactcctact cctgttgctc cggttgggcc tgttggacct
     3961 gtcactccaa atcctgttgc tccggttgca cctgttggac ctgttattcc atttgctccg
     4021 gttgctccgg ttgggcctgt tgggcctgtt actccatctg ctccggttgc acctgttgct
     4081 ccagttgcgc ctgttggacc tgttattcca aatcctattg ggcctgttgg acctgttgga
     4141 cccgtcggac ctgttggacc tgttgggcct cctcttccag ttcctcctgt atttcctgtt
     4201 ggacctgttg ggcctgttgg acctgttgga cccgttgcac ctactcctgg tcctgttgga
     4261 cccgttgggc ctgttgggcc tgttctacct cttggaccca ttggacctgt tggacctaca
     4321 catgatggcg gacagcaatg atgacaatca cagctattat aatcatcacg accactgtta
     4381 caatcatcgt atttatcata gccattgttg taatcattat catcaaatgg tccaaaatat
     4441 ttatttctac tcattattaa aagcacctcc tgatatattt gagcttctaa gctctatata
     4501 taatatgtca aatttagtat tattgtgacc tatcaactat ttttaaattt attaaaataa
     4561 ttttcattgt gcaaaacagc actatcatta ggtttgattt cttttgtttt ttcatgataa
     4621 taaatagctt tatttgattc tcctagcctg tcataacaga cacttaattg tatatatggt
     4681 atatatccat aacaatcatt tgacttaaaa cctccattag tatcattctt atctcttgtt
     4741 agtgctacct tataccaaaa aatagcttct ttatattttt gtctatcaaa catatgcttt
     4801 cctatgtcac aacaaatttc tgctcttggc tcatcaaatt caaaacttct aaacaaagaa
     4861 tataaggcac tcttttcatc attaattaag taataacatg tggctaaatc tctgcaagca
     4921 ctgatacaat cctcaatcca tcctcttgat gagtctaaaa acttagtaaa accttctatt
     4981 gcttctttat acttagcatt atagtacaac tctctagagt aataaaattg gtgtcttggc
     5041 tccaatactt ttccttctga aatcattttt tcaaaaattc taagatttct tagagggtct
     5101 tgtctatgaa gctttttatg agatattgca atgtcagaat aaaatacctc tccagaaaga
     5161 ggtactactt catgaatagg gtcaacccat ttatgattag aacttctttt aaacaatcgt
     5221 tctctataat acgagagagt tgggctacca ttttcatcaa aggatacatt gtattttgcc
     5281 ataacaatat caatggaagt atccaagctt tctttaatct ttaataattt ttctctatca
     5341 gcttctaaaa ttatgtcatc tgcatcaagc cacatcgtat agtctttaga agctttagaa
     5401 aatgaaaaat ttcttgcagc agagaaatca tctatccatt cgaaatcgta caccatgtct
     5461 gtatattttg agactatttc ttttgtggaa tctgtagaac cagtatctac aattataatt
     5521 tcgtctacta tatcctttac acattctaag catctgccta taacttcttc ctcattttta
     5581 acaatcatgc acaaacttat tgtaatcata atgtacaact cctttgtctt ctatatattg
     5641 cagacataag taatatatgg tattttctct tgttttgtta ttaaatttat aaaaactttt
     5701 gacgacagaa agttactaaa aaaccttatc ttttatgtat ttttatggta gaatttatta
     5761 aacttgaaat ttgatactag ttattgaaat aataaaacta tatttaattt catacaaaaa
     5821 agagcatccc ataaactaaa aagttcactt tgagacactc ttatttaata ttctatatat
     5881 atttataaaa cagatatttt aatatgatac tttattcatt cctattcatt atataatcaa
     5941 tcagtccata ctctttagct tctagtgcag tcataaaatt atctctatct gtatctcttc
     6001 taatatcttc tattgattta cctgtatttt cagaaaaaat tctatctaat cgttctttta
     6061 ttttcaatat attatctaca gctattttta catctgttgc ttgaccttta gctcctccca
     6121 ttggctggtg aatcataatc tctgcattag gtaaagcata tctttttcca tgtgttcctc
     6181 ctgcaagtaa aaaagcactc atacttgcag ccataccaat acaaatagtc gatacatcac
     6241 atctgacata attcatagta tcatatatag caaaccctgc tgtaacagag ccaccagggc
     6301 tatttatata tataattata tctgaatctg ggtcttctga ttctaaaaac agtaattgag
     6361 ctactactaa acttgcaata gcatcattaa tttcttctcc tataaatata attctatctt
     6421 ttaataattt tgaatatata tcataagacc tttccccttg acttgtttgt tcaattacat
     6481 gtggtactaa actcatgcta ctttcacctc acaattaata ttaaagttaa gataagaatt
     6541 aatttcatct attctttgtt tacaattcat atttgcataa gaaatatatt tttcgctttg
     6601 aatctgatga tttagattta aaacaaatct ctgttgaata ggataaaatt catctttatt
     6661 tctatatact tgtggagatt ctttatataa atttctaaat gctagtgtaa aagattgatg
     6721 tgtagaatat cctgctgtaa tagctatgtc tataatatat ttgtctgtaa atataagctg
     6781 tctagctgct tcagtgagtc tcctcctctg gatgtattga tgaatagtac atcctacaat
     6841 gtttgtaaac attctgtgta aatggtattt tgaataatta gcaatatcag ctattttatc
     6901 taaatttaga ttttctgtaa gattttcttc tatataatca attatctcca taataacatc
     6961 tgtatttgtt ttcaactcta tcctctcctt ttaagtatta taacctatgc aaaaagtttt
     7021 ttcttaatat aaattgctat cttaatttag tgtatagcaa caaagtatcg ataacacaat
     7081 atcaggtatt tttatacaaa aatattaata tatatttctt ttaaagttta aacttcattg
     7141 catctattat atgtagattg ctatatgttt tatctatgta ccttgattta tatgtattat
     7201 tttgctgagt atttttacac ctttttcaat ttcatcaaaa ctaagatgag cataacctag
     7261 tataatttca tggtcatatt ctaatatttt ctcaattgca tattgttgta taggataaac
     7321 ttttatgcct gcttcaaaaa ttttatgaat taaactttcc gtaaatttaa cattatagaa
     7381 atgagcaact atatgaagcc ctgctgcttc accttttatt ttaaattcat ttttaaattc
     7441 cgtgtttaaa acttttatga ggtacttacg ttttctatta tacaacttct tcattctaaa
     7501 tatgtacttc tctaaacctc catttccaat aaattcagct aatacatgtt gtaatattgt
     7561 ttctgtatga acatcagagt acatttttaa ggttttatag ctttctaaaa tattgtctgg
     7621 taataatata aatccaacac gaatggctgg agataatatt ttactaaaag aacctatgta
     7681 aattacttta tttgggttaa gttcataaag agaactaatt ggttgaccct catatctaaa
     7741 ttcactatca taatcatctt caattatata gtaaccattc tccgttgcat atttaataag
     7801 ctccagtctt ctttgaatag gtaaaatccc tcctaatggg tattgatgag aaggtgtagt
     7861 ataaacaaaa gaaatcccct ttattgattt tattaagttg gtatttattc ccttatcatc
     7921 tactttaact ccaacaactg aatatccaat agatgaaata acctttaata agcctttatg
     7981 aatagggtct tctacagcaa cctttttatt acttttgtat aaaagctgtg aaattaaaga
     8041 taaaccttgt gttgaaccag aaacaatcat aatgtttttg ggattacatc taattcctct
     8101 agtacgaaat aaatacttag atatttccgc tcttaaaacc catacaccag ctgtacttcc
     8161 atatctgaaa tccgaatcag ataaatcata cagtatttgt ttatatagct ttgaaagttc
     8221 tttgcgtgga aatagtttta attctggaac tcctgaacga aaatctatat aatttttttg
     8281 tttattagta tgtaaatctt tttcatctct aaaaatataa tttaacttaa aatcaacttt
     8341 atgccctgat attcctttag ctacaattgt tccatatcca ttccttgttt ccaaatatcc
     8401 ttctgcaatt aattgattat atgcatctaa aactgtatta cgagatacag atagttcttt
     8461 tgataaagtc ctagatgatg gcaatttttg ctcaaacttt aagcttccat tcagaatcat
     8521 atcttttatc tcacaataaa tttgtcttga taatgatata ttactatttc tattaatcgt
     8581 aatccacatt ctaatacctc caaaagtggt tctataaaat tactataaaa atggaactac
     8641 aaaatctact tttaacttgc taagattata tcataaaaca aaaaataaaa aggagtctat
     8701 attatgttag aaatatcaca taaagtgaaa gaaatttatc ccaatattaa atttggagtt
     8761 atggttataa atattacaca ttcaaaacct aataaagaaa attttttaat tcttaaaaac
     8821 tctacaatta aaaatattat agaaaaacat ccagaataca atcgtaaaga aaaaattaaa
     8881 acagagcctg tttcaagtta tataaagtat tacaaaaaat tcaagaaaac ttaccctgta
     8941 ttgcttcaat tagaatctat tctattaaaa tcaaaaggta tcccagatgt aggtgtaaca
     9001 attgagtcaa tgtttttagc agaattgaaa aatcttcttc taacagcagg tcatgacctt
     9061 gataaaatag aattaccttt gaaaatagac ttagcaaatg gaagtgaaca tttttatggt
     9121 ataggtgcta aagaacagat tttgacaaaa gatgatttat ttttatcgga taatattggt
     9181 atattatcta gcattcttaa tggacctgat aatcgaacag ctataacaaa agatactaaa
     9241 aatattatgt attttgtata tggacctgat aaaatatcag aaaaacaaat tcaagaccat
     9301 ttaaatgaca taaaatacta tatttcaagt gcttttccag atttaaaaat taattcaatt
     9361 gatatatttt agttaatata ttaaaatcct cacaaatatt ttgaacaaat aaattagtga
     9421 agtatatatt ctagttaaac tagatatact tcactaaaat taattatata gatattattt
     9481 atctaaggat attatttatt ttgagtttta tttataataa acactttgtt acatttaacc
     9541 tatgaataac ttaattttat aattaaagaa tttcataaga aacaatttca cttaaaggaa
     9601 cacgagtttt ttcatgtcta tctgggctat ctgctacctt agattcatat cccatcaata
     9661 aaatatttat tggttctaga ttatctggca aactaaactc ttctctaatt atatctggat
     9721 taaaatagca tacccaaaca cttgccaatc caagttcagt tgcttgtagc atcatatggt
     9781 ctgtaactat acttgtatca atatctgtaa gttgcttccc atcaaaaggt cttgtccaaa
     9841 ccttctcttt atctccacac acaagaattg ctaatggagc atcatatata ttggcagcct
     9901 tggaaagttt atttagaccc tctttttcct gaataacaat caatctttga ggttgacgat
     9961 taccaccagt tggagctatt cttgcaacat ctaaaacctt atcaagtttt tctttttcaa
    10021 cctttctatc ttgataatta cggcaagaat atcttttttt tgcaagttca acgaaattca
    10081 tttatttacc tcctattgtt ttattagact aagttgatga tttatttaac ctatgctata
    10141 attttagcac tatggtaata tattacaata atgcactttt ttgtaatata gtacctaaaa
    10201 agatacttta aaataaataa aggagtccaa aaatgaaaaa atgtttagat aattacagtt
    10261 gcccaataga agcaacactt gcattgattg gtggtaaata taagacactt atactttggc
    10321 atcttaaaga cactatattg aggttcaatg aattaaaaaa attaatccct aaggcaacac
    10381 ctaaaatgtt aactcaacaa ttacgtgaat tagaatcaga tggtttaatc ataagagtgg
    10441 tttatcctgt tgttcctcca aaagtagaat actcactatc tgattttgga aagagtatta
    10501 ttccaatttt agattccatg tgcgactggg gttctgatta cttggaaaag ctctaaacta
    10561 ttacagttta aatcccatag ctaatttaac ttcatccagt tgttttttag atatcaacat
    10621 ttctaaaagc ttaaaagcta catgtggagc tgtttctgta taatatgagg ttataatgtt
    10681 ttgatttaca acagttggtt cattaactac atttacatca aactcactta actgtctttg
    10741 tcttttacta tttttcaaat gatatgtagt agctttacga ttttttaaaa cacaactttt
    10801 tccaatcagc aatgctgaca cacaaataaa agcgattatt ttttctttta aattaaactc
    10861 ccttattaga tttaaatatg atgacattct aatgcagtat catattccaa tatagttttc
    10921 ttaaattctt ccatactttt agataaatcc gtattgataa atacaaaagc caaaagctta
    10981 tattttattt tttcctgatt aatttgaata gtgtactttt gaattaaatt taattgctca
    11041 attttcctta tatgctctga gactgctggt attgataaat taatttttct gcttatttca
    11101 gaagttgaaa cctaccattc tttcttagag aattaattat ttttaaatct atctcatcca
    11161 gacccactca ccgccttaat tatttaatat aatttaagct aacaatttac attaagtaaa
    11221 taattttaat tatttcaata aaacttaata caaatatatt attttttctt agaattttag
    11281 cttatttaat caaaatacat attacactta aaattattta agttgaatta atgtttttat
    11341 tttgtataat atattgctta tttttgcgac aataaaagat actccataat ttatgaagta
    11401 cttttactat atgtttaatc atttagttat tatatcagtt actttcatac tattatattt
    11461 ttatttctaa taattatata tgtacattag catatcattg aaaatttaat aatattatcc
    11521 atctacttct acatgttgca atatttaata aagatagtat acctgtatca aaattataaa
    11581 tctcgtaatc ttaatttttt aatagattat aaaattttat tggtggtgag tcttcaaata
    11641 actttgtaat gatagattta ctaaattaat aggttatgta gcaaatataa ctttcttatt
    11701 gactataact aagtattatg ataacatgat ttaagctata attaataaaa tatattttaa
    11761 gtaaataagg caatatacaa agtacaaaag tacaatttaa atatagataa actagaatta
    11821 atactaagat taggatgtga ataattatga tttatataga attagttaaa cttgttagaa
    11881 aacttaactc tacacaaatg tatacgatga agcgttgtgt agaggttaat ctgaaagctt
    11941 aaagctttct atcttcatcg gcaaatatag gtttagtgta gtttttgggc tatgcttatt
    12001 taaaattacc tatttgccga tagataatat agattttctg gtcatagaca acaatgcttg
    12061 tctatgacct tttgtttttc caaaagcaga ggtcggcatt ttataatgtc attcctctgc
    12121 tttttttatt tccataaatt ttttaataaa agaaaaggag tttgaattat gagtttatta
    12181 aaagtaacta atttatcaca atgttttatg gataaatcac tgtatgagaa agctaacttt
    12241 gatttattca aaggtgaaca tataggtgta gttggccaaa atggtacagg caaaagtaca
    12301 ttaattaaaa ttttattggg agaagttatt ccagattcag gagaaatcaa gtggcaacct
    12361 aatatcaata taggccattt agaccaatat gcagaaatca atagagatac aacaatatca
    12421 ctctatttac acactgcatt tgaagaactt tataaaatag aaaaggagat gaatttactc
    12481 tatcaagaaa gtgctatatc tggaaatgag caacatctaa tcaaagcatc agattatcag
    12541 gaacaattaa tagcaaataa tttctattct atagataatg aagtaaataa aatagcaaat
    12601 ggtcttggat tagattcaat aggaatgaat cgtgttgttg gggagcttag cggtgggcaa
    12661 agggcaaagg taattttagc aaaattgcta ctttctaacc atgaggtttt attattagac
    12721 gaaccaacaa actttttaga taaagaacac gttgaatggc tctcaaatta tttaaataca
    12781 tttagtggag catttattgt agtttctcac gattttgact ttttagagaa aatttctaca
    12841 ggtattcttg atatagaatt tggtatgatt aagaaatatc atggaaaata ttcagagttc
    12901 cttaaacaaa aattacattt aagagaggat tatattagaa gatatcaatc acaacaaaag
    12961 aaaatagaaa aagaagaggc atttatacgt aaaaacaaag ctggagtaaa ttcaaaaatt
    13021 gcaagaggaa gacaaaaaca attggataaa atagaaagaa tagctcctcc tggttttaca
    13081 ggaaaaccaa atataaaatt ttcagaaatt gaaatatctg ctcaaaatgc tcttacagta
    13141 acaaatcttg aagttggcta ctactattct ttgcttccaa aattaaattt ctctgttgat
    13201 gggggtcaaa aaatagttat aacgggtttt aatggaattg gtaaatctac tttgttaaaa
    13261 acattagtta aagatattcc ttgtatttct ggagatttcc agttttctga acaagtgaaa
    13321 cttgcttatt atgagcaaga tttaaaatgg gaaaatccta ctaaaacacc gcttcaaata
    13381 gtagcagata aatatccgaa attgaataca aaagagatta gacgtcatct agccagatgt
    13441 ggcgtaaagg aagaacatgt ttcaaggagt gtatctacat taagtggtgg tgaacaatct
    13501 aaggtaaaat tatgttgtat gatgttattc ccttgtaatt ttttgatttt agatgagcca
    13561 actaaccact ttgatgcaga aacaaaggat gctttacaaa atgctttgaa acagtttaga
    13621 ggaagtataa ttctagtttc ccatgaagaa aaattttata aaggctggat tgacaaagta
    13681 tttaatatag aaaaacaatt agtgtaggtt tatatacaat atgcgatatt gtttaattag
    13741 catttcaatg caaattttaa tctcctagtt aatgtttcac tgcaagtaaa ctaaaaaata
    13801 aatatttatt agagcataaa gtgcattacc acggtataaa tttaatgagg ctatctcaaa
    13861 atagagataa gcctcttctt cattattgat ataacaaaaa tacatttgat ttcacacaaa
    13921 aaagaatgtc tcattaacta acaaattgaa tttgagacac cttcattgat actaagatct
    13981 attctaatcg attctattca caagtttata tcctagacct ttaactgtta taagtatttt
    14041 aggatttgag gggttatctt caattttttc tcttatatgt cgtatatgca ccataattgt
    14101 attgtcacaa atactactgt atactcccca tacttgttca tagagtcttt cttttcctat
    14161 aattttattt acattttgag ccatgtagct taaaagatga tactcccttc cagttaactc
    14221 aatctctttt ctatctttat atacacggtt tccttctata tcaatagtaa tatctcctat
    14281 cttaataact gaactatctg atggtacaat actttgatac tgttgtctac gtaattgcgc
    14341 tttaactcga aaaacaattt ctcttggact gaatggcttt gttatatagt catctccccc
    14401 actactaaga cctagtattt tgtcaatatc atcatttttt gatgagagaa aaagaataga
    14461 acagtatgaa aactctcgaa tttttttaca cacttctatg ccatctatat ctggtaacat
    14521 tatatcaaga atgacaacat ctggacatgc tatcttacac agcgaaatag catctaaacc
    14581 attataagct ttaataatgt ttttaaaacc atcatttata agtacttctt caattaaatc
    14641 tactatatct ttttcatcat caacaagtaa tattttttta ttaaaatatg tatccatatt
    14701 gaaatctctc cataaaaatt tattatattc taatcttgca gtatcactat cttgtttttt
    14761 tatattcact actcttgctt ttacattact aatagtaaca tctctaatat acaaattcaa
    14821 tcactatgaa aattaagata cgtttcctta aaataaagta tatgatacat taaaacctat
    14881 agaaaattaa tttcatccaa agtttataat attagactaa tacacttaca gatacagatt
    14941 aatacaatag taaaataaaa ggagttgtct taaaatcgac tttttctaat caaactttaa
    15001 gttcaactcc ccttttaaac ttttatatgt tatttttatt aattctttat atcaattata
    15061 actttaattt tcaatagtat ctatctacca ctaattgaat tacttattaa aacataaaat
    15121 atctacctaa actatttatt taatatctac atatatttat atctattctt atgcttacat
    15181 atacaaaaaa cggttaaaaa taaagttaaa atttcagcac ttggtactgc taaccatatc
    15241 ccatttatat ttaacatatt tggcaatatc aataaaccta tagttataaa tccaaatgta
    15301 cgtagaaaag ataatattgc agacaccttg ccatttgaca atgctgtaaa catagatgag
    15361 gtaaaaatat tatatccaca aaaaataaaa ctaaaagaaa atatataaaa tccagacctt
    15421 gcaatttcat aaactcggct tcctctttga gaaaaaatct ctacaatgat tggtgaacat
    15481 gatatagaaa agataaatac caataaagat gccactgaaa taaataatat acaaatctta
    15541 aaaacatgat ttaactgtgt attattttca cttccataat tataacttat tattggtgca
    15601 acacccattg agaaacctat ataaagcgaa gttaaaagaa attgagaata aataattatt
    15661 gtaatagctg caactccatc ttcactaatt aatttcatca tcatagcatt aaataaaaaa
    15721 gtagtaactg ctgttgatag ttgacccacc atttcagatg aaccattaaa acaagcttca
    15781 aataatattc ttttatctag tctgggtata caaaatttaa gtaccccttt attttttgaa
    15841 aagaaaacca tacctgaaat ggtaggaatt aggtatccta ctccagttgc aagtgctgct
    15901 ccactaatac ccatttgtaa cagaacaata aacacatagt caagaattat attagcacac
    15961 cctgcaccta acactagcca taatccaaat tgaggctttc cagctgttac aaataaacat
    16021 tgaaataata cttgtagtat attcgcagaa gcaaaaatca agataataaa aatatatgaa
    16081 tgacaatatt taattaaaac ttcacttgct cctaaccata taatgatata atccataaat
    16141 acaataccta taccagtaat tattacccca attacaactc ctgataatac gattaaagag
    16201 aaagctttat ttgctccctc aatatcacca tttcccatct tacgtgctac aatagcactt
    16261 cctccagtgg caagcatagt tccaattcca actataagat taataattgg acatacaata
    16321 ttaattgctg atagagcatt tgtattaata aatcttgata caaatatagt atcgacgatt
    16381 gtatacaatc ccataaaaat catcataaaa atagtaggaa atgcaaactt caatagagta
    16441 aataaattaa atctttgtgc cagtaaatta tcttgctcat aaagattatc ttgttcatga
    16501 ttttctgaat aatatacatc actcattttg tttatttttc tgtacattaa ttatttttaa
    16561 aatatattcc aaacaattag acatttacag acctcctttc tgcataaaaa ttatatctaa
    16621 ttatttggat atagttttaa ttaatcttgc ttttttacac aattatattt atactaaagt
    16681 aacttttaaa tccttacttt aatcatttta tagctttcaa tgcctttagt gtaaatactc
    16741 gtttacatag tctagtgtca tgtgaaacgt atttatatat aattatattg tctattttcg
    16801 ccaatttatt aactacttgc acttttataa tgtctcagac ctaacttcca aaatctccac
    16861 ataaacaatg taaacgaaaa tacaattaaa attgaatata ttaatccatt aatagttatt
    16921 gttccagcca aaatttgagt tggaattgtg gacataattc catatggtaa gattaaatag
    16981 aataatactt taaaaacacc ttcatatatt acaccaggaa ttttcatatt cattggcaat
    17041 aaattatctt ctaatctcat tatcgcagaa gatgatataa caaaaaatga aactgttcta
    17101 agtataatac atacatcata aaaaagtaat gtcatcaata gcaccatgaa aatatatatt
    17161 attattatga ctaaagttat ctctgagttt aattcagaga ttccatataa aacaataagt
    17221 atacttgcta aaattaatgg tgatgaacca atattaatat tttcaaatgt taacctaaat
    17281 agtgggtcta ttggttttgt aatatagtag tctaattctc cttcctgaat ttttcgtgga
    17341 atatcataaa taccaaaaaa gaaaatcgtc atatttatcg catttattaa tgagaaagtt
    17401 cctataaata ttaacatctc tccttgttgc catcccccta ttgagtctac atgagaatat
    17461 atactattaa acattagaag ttgtaatata aataatgaac tatctacaaa aaatgctcca
    17521 aaaaaatcaa atctaaatac catcatcttt gataatttca tttttaataa cataaatatt
    17581 attttcaaat tttttttcat catataccca ccccatcaaa taatgttctc attcttttat
    17641 acataacttt atttactaca gaaaagaata aaacccataa tgctaaaata attaatcctt
    17701 gtattgcttc attgctgttt ctacctatta gtaacataga tggcaaatat gttgtataat
    17761 aaaatggaaa taccttcata acttttacta tagtttctgg taaaagcaca agtggtatca
    17821 ttgttcctgt aataaattca acaatatttt ctattatcat tctaaaaaaa ctaatctcaa
    17881 gaaatttaaa tgacaaaatc ccaataaaga agtggagttt catcataaaa ataagtccta
    17941 gaaaaatcat aaaaattgaa attaatattt gaattggatt tgatgtaaag gcaaaattta
    18001 ttttaaatat aaaaatccat acaaatgcag aaatcatatt aaatacaaaa taaaaacatg
    18061 tcattccaaa atttttagca ataaaataat tttgaacatt aattggaata atcatgtact
    18121 ttgaaaatgt gcctaatttt actcgattac atatctcttc actggtactc ttcgacatat
    18181 caatacctga taaaaatgag cttattatat agtaagacaa catagagtta aatgtaaaac
    18241 cagagactat tttattttcg ccaaaaattg ctttccataa aatataagca aataaaattt
    18301 ttacaatcgt aaacatcata ttaactacca catcaaatct ccagataagt tgcactttaa
    18361 agttaatttt ggctacttca taataccttc taatactctg tttaaattta taaaacattg
    18421 aagaatttga acttgcttca ttatagttgc tcataatact catcacttcc tttcttatat
    18481 attctctcta caatattaac tatatcttct tcttcaatca ttacatcttt aacatcatat
    18541 ctatcaaaaa tccatttaat cgtttcattt cctctttctt ttggcacaac tactgaggtc
    18601 ttatgatttg tttgttcaac aactttacaa tcttttgaaa atacaatgtt agtttcattg
    18661 gaaaaactaa ctgttatttt tttatatttt tgaaaatgat taaatagttc ctctgtagag
    18721 ccatcatata ttttacggct attttctaca acaatacttc tactacagag actcttaata
    18781 tcttccatat aatgagaagt aagaataata gtagttcctt ttgtttcatt tacctctttt
    18841 agaaaatacc taatttgttt ttgggctaca gcatctaaac ctatagttgg ttcatccaaa
    18901 aataatattt tgggattatg tagaagggct actattagtt ccattttcat tctttctcct
    18961 agggaaagtg tcctaacttg aacatttaaa tattcagata cctcaaataa ttcgataaag
    19021 taatccaaat tttttttata ttcttcatta gatatatcat ataattcttt aaataaaaga
    19081 aacgtatctg ctggtgtcaa ttcaaagaat agttgacttt tttgacccat aacaatagca
    19141 tattgttttt taaaattatt ttctaattta ttagggtaat aacccataac agatatttct
    19201 ccagaagatg gtgcaataat accagttaac atcttaataa gagtagtttt tccagctcca
    19261 ttttgaccta ttaatccaac aaattctcct tcttctatct ttaaatcaaa tgatgatata
    19321 gctgtttttt ctgtatattt cctattaaat aaagacttta cactccctat aaatcctgcc
    19381 tttttctcaa atcttctata agatttagtc agttcattaa gttcaattat gctcatttta
    19441 atcgcctcca tatttcataa tttatataaa aaaatccaca ggtatatatc tgcctttttc
    19501 tatgcttata tttaacagca caaaaacaga aaactcctgt ggactagaaa agttaatgct
    19561 ctctatttca acatagttat caaaataata ctatacaaaa ttaataaaag tgtagcagat
    19621 taaaacctac tacaccataa tttaacaaag taatatatat tttaaatact atttgttgtc
    19681 atatgtcagt tatctataaa ggcagaataa gacacacaaa ttaaatgtat taaaaataca
    19741 cttaaaattt ctgattatac agaatatatg tgtctccaac tatttaattg ttggttacca
    19801 ttatacaact ccgacatcaa ggcactcctc tcataatatt attatcaaca tcatatcata
    19861 aaggttattt atgttcaagt atagattcat atactaatat atttagttta tttcctcagg
    19921 gttgaattta aatttcattt ataatattca tttataaatt aagaatataa tatgcatatt
    19981 aaaacttgtt atttttcttt aatcttttta tcataaaaga tatacttttt acctatacag
    20041 gatgtaattt cttcagttct atattataat aagattgtaa taagggttca acttataata
    20101 cattaatata taaactgtaa atcttaaggg ggtaatctat gaaaaataat acaacacaaa
    20161 aaagattaag agatttatca aaaaaaattt ggaatattta tattttaaat ccagaagaag
    20221 aaggcattaa atttattatt tctttgttag atgacaacct tacattaatt ggaacaggaa
    20281 aacatgaatt ttacgaaaca ttagaagaat ttattatagg tcttgaaaaa gaccaagtag
    20341 aatcaaatca aatagacttt gaaattatag atgagtggta ttcatgtacc aaagtcacag
    20401 atgaaacttt tatagtatat ggtactcttt gggtaataga aaaagattac ctagaaaaag
    20461 atatctatgt agaaatggat actcgcttta ctatggtata cagagttaaa gatgatataa
    20521 ttaaacttat ccatgttcac cattctattc caaactttga ccaaatgaaa gatgagtatt
    20581 accctaaaac aataactgaa aaagcacaag aagcactagc aatggcaaat gaatttaaac
    20641 taaaatcaga aaaagacctt atgactggac tatacaacag acattttttt gaagtacaca
    20701 taaaagaaat gcttaaaacc gtttcacacg gatactttta tatctttgat ttagataatt
    20761 ttaaacaggt aaatgatatc tttggtcata ttcgaggaga tgaaatacta atacactttt
    20821 caaatatttt gactaaagtc ttcataagtg atgctattat tggaagactt ggtggagatg
    20881 aatttgctgt ttttgaatat agtaatcaat caaaagagga tgttgaaaat aaagcaaaaa
    20941 aagttttaga attgtgctta gagaataatt cttgttctat aggtatatct agattagaaa
    21001 ataactctga tactttccaa tctttataca aacaatcgga ttatgcttta tattattcaa
    21061 aacgaaataa taaaggaaac tttagttggt tttagtgcaa aagatattaa aataggcaaa
    21121 tttctcagag tatcttgttt tacgtactaa taggtaaggt aaacaacaac ctatctttgc
    21181 atatatttat ataaaccaac tattattaat agagctacaa tagtcatcat acccactatt
    21241 atagaatatt ataaactaaa aatattatta acatgattaa tattatattt taataatttt
    21301 atttttaaaa ataacaccaa aatattatat tttttgatta aaactgatgc tgatataaaa
    21361 aattctacta aaaaaatact taaaaaggct ctataaatag ccttttttac ttttattgat
    21421 taaatttaat ataaaattcc ttattaaatt tcaaattaat aaaaaaaaga ttccacaaga
    21481 agccttccat atttttattg attaaatcct aatatagaca atgccttagc atcatagtaa
    21541 gtagtcatct ctctcgtcgc atcctttaac ttaaggtaat caaaatctaa tgttccacca
    21601 aaaatagaag tgtattgaaa ttgtaccttt atgttttcat aatataataa acttatttat
    21661 taaaacatat tgtttaaagc agtacattta tatgtttttt ttgttcatct gttttatcaa
    21721 atatattagt ctttgaattt tgtttgtatt cttcagcatc tttatctaac ttttctattc
    21781 tcgactcaag tttcattatt tcttcttgtg ttaaatttgt aaaattttta agcatatttt
    21841 caagctcttc acgagtttta cctgctaagg ataagtcctc agatatcttc tcttttttat
    21901 tagaatcctc tttataatcc tttttttgtt ctaactcttc taatttttca tcatttaaca
    21961 tttcttcttc aactttttca ttaaactctt tagtgattaa agattctttt tcatcacttg
    22021 tatttagata agttgaattt tcatataaca ttgtactttt atttttatct tctataatgc
    22081 tatttttaat acctatttct atattagaaa agttattagt tgtttctctt atttctgatt
    22141 tatataagtt cttaattgct tcgtttattt ttttagtata aacctcttgt ctatctttta
    22201 aatctctaat tctatcatta agttcttgct tttgtttcat aatattagat aaataagtgt
    22261 cttttcctac agtttcattt ttcttaacta tactttcatt tattcttgta ttatttatat
    22321 tactttcatg tctaaatgaa tattgacttc tatattgact agatattttc atttatttca
    22381 cctctctaaa acaaatttat gttttataaa aagccaactt aacttaatta tattttatca
    22441 tcaaaagtat acatttacaa atattagtta atagttctat aggttcgagc attattttca
    22501 acaaaaaatt tttattataa attaaaacaa taatttttat aaatatctta tttatatttt
    22561 ataatttata tatttttact ttagaaatta tcaatattac agttttgctt ttaagaaaca
    22621 tctctatcat acataagcat atactctatt atgtattagt ataaatatgc ctcttcttat
    22681 ctcacataag aactctttat aaaagaacct atcataacaa acatgtatac attatcatat
    22741 gtatatatca ttatataaaa agtcaaactt tattaaaaaa attaataaat tgccttaaat
    22801 aataccataa atcaaatttg ccatcaaaat cacattaaag taataaattg atggcaaatc
    22861 taatatatta ataatatata gagtcataga acgaacagaa caaaaaaact acactcatct
    22921 tctaatcgtc ttatttattt ttgagatatt tttaaatttc ttttcttttt ttgctaagta
    22981 ttcgctttta ttgtctgcaa atactgcctc agttttaagc ctacgatagg attcccatct
    23041 tttaggcgaa agttcttgat gagcaatagc ttcccaaata gcacagcctg gttctgaagt
    23101 atgagaacaa ttacgaaaat gacattttcc gaaataagct tctatatctg caaaactttt
    23161 atctacacct tccgaaacat cccacattcc caactctctc atacctggtg tgtcaataac
    23221 aataccacca cctgaaatta aaaataactc tcgtctagtt gtggcatgtc ttcctttatc
    23281 atcagctatg cgaatttcct ttgtatttaa aaattctcca cccagcagac aattaattaa
    23341 tgaagatttt ccaactcctg aagaaccaag cagagcaata gtataacctg gtttgatata
    23401 cttagaaatt tgttgacaac catctgactc tttagctgat gtaacaacta catctacacc
    23461 caaggctata gaattaacta cttgtaattt acgatgtaca ttgtcacata agtccgattt
    23521 ggtaagtact actaccggga cagctccact ttcccatgtt aaagacaaat atctctctaa
    23581 tcgatgagtg ttaaaatctt tattcagtga catacacaaa aaaacaatgt caatgttagc
    23641 tgcaactacc tgttcctcat ttgcctttcc agcagcctta cgcacaaaca agctttttct
    23701 atgaagcaca tgatgaataa tagcattacc atttttatca ttacaacggt caagtataac
    23761 aaaatcacca actgttggaa aatcagatgg tatagtagct tcaaaacgta gttttcctga
    23821 aacctctgca aaaactatac cacctgtaca tacagcttga taaaggttct tttcctgtga
    23881 tataatgcga gcaatgtaca aatcatgata tttcatactc tgagtaataa aattactatt
    23941 tagaccataa tcttgtaaat caatctcttt cataccattc attctgtttc ctccttctcc
    24001 atcttttcag tgattctctc tagtgggaaa ggtggttgtg ccagtggttt taatgcaatt
    24061 gacattaatt tcactggatt atcatcagct gcaatacggt tagaactaag atgtccacat
    24121 cgtgtacaac gatgaataat tgcccattcg ccattttttc tcacccacac tccaataggt
    24181 tccatattag catcacaatc tgcagcacgg tcaccaggaa tgatatccac atgaagacta
    24241 tgtaagcaat gtggacaatg attcctatgt tgtgtaccag ctccttcagg tactacaatg
    24301 caaccacagt ttttgcaaat aaagttatcc aaacaggaat tttcctgata ataagctcgt
    24361 tttctatttt tataattcat ttttatcgcc tccatatctt gtgttttata caaaaaaatc
    24421 cacaggtatt tatatctgcc tttttgtgtg gtatatatat ttgcctacac aaaaacagaa
    24481 aactcctgtg gactagaaaa tttaatatct tctatttcaa cataactata ttcaaaataa
    24541 tactatgtaa aattaataaa agtgtagcag attaaagccc actacaccac aatttaacaa
    24601 agtaatatgt aatattatta tttgttgtcg aatgttagtt atctataaag gcagagtaag
    24661 acacaacaat taaatgtatc aaaaatacac ttaaaaattc tgattaaaca gaacccatat
    24721 gcgcctccaa ctatttattt gttggttacc attatataca actctgacac caggcaagac
    24781 actcctttac taataattat tattgaaatt ttatcataaa atatgagtat gttcaagtat
    24841 aatttaacat attcatatat ttatgtttat cttatttttt tattctatag aatctagtaa
    24901 tcttttgaaa ttcaatattc attcaatatt aatcataaaa attaaccgct attatttctt
    24961 ttatcatctt atatctctcc ctcaatttat ctaatttaag ttaataacaa aggtctttta
    25021 aacaaaacgt ataatcaagc tcttccatat attcttacat gaatagtata tttttttata
    25081 taaaataacg ttcatattta taaatttatt taattttcaa acaagtatat tgaataataa
    25141 tcaattctat tgtattattg taattgtaga ataaaactaa atcggcaaaa ctagagaaat
    25201 ttagtgacgc aaagctatag ggactaacgc ttataaaata aaatatgagt tatgtcagcc
    25261 agttgccaaa aagatatatt ctttttgttt ttatgaaagt tttttagggg gataataata
    25321 taatgtttag agataaaatg gatagatgta cacatatgtt gactgcttat attggtagtt
    25381 catatgatta ttgtgatttt atagatacac aactagatga ttttatacta gagtacggag
    25441 aaaatgtagt agaatcttgt ctgcatcaag tgatggtatt agtaagtaag tacaattaaa
    25501 tagagttggt tttctagaga acccttttta gttttatcta ctttaaatag tcttatgtta
    25561 gaaaactaat taaaatagat ttctagtatt catagtttta ttttttattt aaaatacatg
    25621 taataaagat gtaaatttgt atcaaaaaag aaatatgata acttaaattt tcttatctat
    25681 atgaaaataa atatctctta aaatgaaatt ctgtaaacat aaatgatttt taagtttgaa
    25741 ggattaaatt aacaaaatta taaatttgca aataagctat attaaaaaat ataataattt
    25801 tttatataac ttattctttt ataactttta attttaaaag aggagaatgt atataagaat
    25861 attcaatgta ctagaaaaaa tcaaaagaaa tattagaaga aatggatatt gagtaatcaa
    25921 agagaagatt ttgatactac aaatgatatg tttcaggaaa gcattcctat cacaacaaaa
    25981 attattcttg acgatatacc ttcacatgat gaattaaatc atgttttttc aaaaggttgt
    26041 gaatgaaaaa tgaaaaagag aaaaattgta ttaatcacat tactattaat aggtgttttg
    26101 ttattaggag gtatcctata taatcttttt ttagtaaaaa cagctaatat ttcaatgcta
    26161 aaggaatctt ggaatttgga tataccaata cctaacaaag aaattgaagt atttgatact
    26221 caagatagta ttaatggaga tggacaaagt tattttattc aagaattttc tgaaaaaaat
    26281 ttcaaaaaag tttttaattt aaaaggtggt atagttgtaa gcaaagataa tattaatgaa
    26341 atagaaaaat atattgataa atttaaaaga gactctgtta acattaataa aagtaataaa
    26401 aataaaattg aagaagattt taaaaaatat aagttagaag ttaaaaaaga tgataagtat
    26461 atatataaga gaaattatga aaactatgta gttttaatta taaaaaaaga tgaacaaaaa
    26521 ttatacagtt taatatggaa tcagtaggta catatgtatt attaagaatt ataaataata
    26581 aaaataaatt ttagtcaata tacaaaagcc ttttaaattg tctggaaatc acctcttcat
    26641 ttgttataaa aacatacaac aaatgaagag gtgattttat ggtttttaaa aaaataatta
    26701 taagtggata tgtgctttca catgtttatc aacatttgta atgcctatat ttactaatga
    26761 attataatat aaaaatatta aataatattc aactatagat tatgtaaatt attctatgaa
    26821 aaaaatgagt tgtataaaat ttggaaactg tagattgacg atttctttta aaattacaat
    26881 tataataagt tctatagagt taaaaataaa actttagaga tttttataac attgtagact
    26941 aaatttgcca ccaaaattac tttacagtgg caaatcggtg gcaaatacaa tatattatta
    27001 tcatataacc tatataaaca ttactattgc ttgattatct tagctacagt ttccacatga
    27061 gtagaatgag ggaacatatc tacaggttgt gcctcaacac atttaaatcc gtgaacattt
    27121 agataatcta aatctcttgc taaagtagaa ggattacaag aaacatagac aattctttcc
    27181 ggactcattg aaacaatagt ctctaatacc ttttcgtcac atccctttct aggtgggtct
    27241 acaactacta cattagcagt cttaccctct ctatacatct taggtacaat ttcctctgcc
    27301 ttcccaacat aaaattcagc attatgcata ttgtttaatt tagcatttat cttagcatct
    27361 tttatggcat catctataat ttctattcca taaacctttt tagccttttg tgccaaaaat
    27421 aaagatattg ttcctatccc acagtaaata tcaaaaacag tatcagtctc atttaaatct
    27481 gcatattcaa gagccttatc atacaatact ttagtttgga caggatttac ttggaaaaat
    27541 gataatggcg aaatctcaaa cactaagtca cctatataat catttatttt tccatctcca
    27601 tatataacta tattttcttt tcctagaatg gcattcgtat ctttttgatt tacatttaca
    27661 accaaagtct taaatccagg tatattttcc ttaagaactg aagctaattc tttaagataa
    27721 ggaagtttgt ttccattcgc tactaataca accattactt ctttagttgt aaaacctatt
    27781 ttggttacta aatgcctaat caatcctgta tgagtctttt catcatatat acttacctta
    27841 taagctctta tatatgtttt tattatttta acaattttat catttatctc atgttgtatt
    27901 acacattttt ctgtcgatat tacatcatga gtcttttttt tataaaaacc aataattgga
    27961 acaccattat tcttttgtat tggaaattgt gctttatttc tatatctata tggattatcc
    28021 attcctatag tgtcatgaac ttctacatct tctaacttac ctattctcga aagtacttgt
    28081 ttaacttcat ttgttttcat ttcaagttgt ttattataat ctaaatcttg tatctgacac
    28141 cctccacaat ccctgagatt gtcactacac actcttttca ccctgaatgg agacttttct
    28201 attatctcaa caatatctcc tacagcataa tttttcttta ctttattaat cctaacttta
    28261 actttgtcct gtattaatcc gccctctaca aaaactgtaa taccattgta ctttcctact
    28321 cctactccgc cttgaccaat gtctactata tctacaatat acacctcgtt tttcgaaagc
    28381 ataaatcacc ctccaatcaa tctattatat ttaaatcttt acaaactttt ttctttaaat
    28441 ttatattaaa atattgctat taattaaact atatttttta ctaagctaca atattttatt
    28501 ttaccaaaaa aaaaggagct tataaagccc cttggtaaat aaatttatta tttttcttat
    28561 aaaactctag ttgaacctct atataccaca cctcttgatg cgtccacagt tacaacttct
    28621 ccatctttta ctagatttgt tatgtcagtt gcagacacaa taactggtat atctaaattt
    28681 atacctacaa tagctgtatg tgatgtcatt ccaccattct ctgttactac agctcctgct
    28741 ttttctatat aattgttcat ttcagcatca gtagcagtag aaacaagtat gtctccttca
    28801 ttaaagtcta cacaagtatc tccattcttt atcacacgaa ctttaccttc tactgtttga
    28861 gtacctacac ctataccttg cacaatttct tcgcttatta catgaacctt tattaagtta
    28921 gtagttccac ttactcctac tggtactcca gcagttataa ctactaattc tccattatct
    28981 atataatcag cttgtctagc tgcctcaatt gccttttcta taacttcatc tgtatttcct
    29041 gcaacagaag acttaactgg atatactccc catgtaagag ctaatttatt catagttttt
    29101 tcattatttg tagtagctat tattggagat tttggtctaa atttagatac cattctagca
    29161 gtatatcctg aagaagtaga tgttattata gctgatgcat ttaaatctac tgctgttgta
    29221 caagttgcat ggcttattgc atctgttaca gtaacattgt tagtaccatt ttcctttaat
    29281 aatctatcat aatctaaagt ctcttctgtt ctttttgcta ttgtagccat catttttact
    29341 gcttctacag gatattttcc agcagcagtt tctccagata acattatcgc atctgttcca
    29401 tcatatatag cattagcaac gtctgtaact tctgctcttg ttggtcttgg atttcttatc
    29461 atagaatcaa gcatttgagt ggcagtgaca actggctttg ctaattcatt acattttttt
    29521 atcatcattt tttgaactat tggcatctct tcagttggta tctcaacacc taagtcacct
    29581 ctagctacca ttataccatc agaaactttt aatatttcat ctagattctc tacaccttct
    29641 tggttttcta ttttagatat tatttgtata tcagtcgcat tattgttctc taatacttct
    29701 cttattgcta gtacatcaga tgcctttctt acaaaagaag cagctatata atctattcct
    29761 tgacttattc caaattctat atcgcttata tctttaggag ttattgctgg taaatttatt
    29821 ttaacaccag gtacatttac tcctttatga tttttaacta ttcctgaatt ttcaacaaca
    29881 caaattatat cttctccatt tatttctttt actcttaagc caactaaacc atcatctatt
    29941 agtatagaat ctcctgattt aacatcttca gcaagacctt tatagcttac tgtacacatt
    30001 tctttagtcc ccataatatc tttcatagtt atagtgaact tttgaccttc ttctaaaaat
    30061 acctctgggt cttcaaagtt acctgttcta atttctggac cttttgtatc taataatata
    30121 gcaactggct tatttaattt ttctctaact ttctttgcca tatctattct ttctttatgt
    30181 tcttcatgtg aaccatgaga aaagttaaat ctacacacat ttagaccatt ttgcataagt
    30241 tgagttaaaa cttcctcact ttgtgatgct ggacctagtg tacaaacaat ttttgtcttc
    30301 tttacattat ttaacatatt tgctcctcct gagatattat tccacagatt tatttttaat
    30361 actaaaactt atatagataa tatttttgcc atctcataag cttctttatc aaatactttc
    30421 ttttgagcta aagcttcact tatttctaag tcaattattt tgttttcttt tattcctacg
    30481 actctagctg attttccatc taataataat tctactgctc ttactccaag tctacttgct
    30541 agtattctat cagatacagt tgggcttcct cctctttgga catgacccaa cacagttact
    30601 cttaaatctg ctcctgactc ttttttaagt tccttttcta aatcgctggc acttccaact
    30661 ccttctgcta aaacgattat actatgtctc ttacctcttt tttgagtagt ctttaatctt
    30721 aaagcaactt catctactgt aatttctact tctggtacta ttatagtttc cgctcctcct
    30781 gcaagacctg catataatgc taaatctcca cagtgtcttc ccataacttc tactatatta
    30841 actctttcat gagacgatga tgtatctctt atcttaccta tagcatctat aatagtattc
    30901 attgcagtat caaatcctat agtatagtct gtatatgcta aatcgttatc tatagttcct
    30961 ggtataccta tagctgggaa tcctaagtca ctaagttttt gagctcctac gaatgaacca
    31021 tctccaccaa ttacaactaa gcaatcgatt ttgtactttt taagaatttt tactgctttt
    31081 aatctacctt cttctgtttt aaattcttca catctagaag attttaatat tgttcctccc
    31141 ctgtgtataa tatctccaac agaagatagg ttcatttcag ttaaatcttc ttctagtaat
    31201 cccttatacc ctctattgat tccatatact ttgcatccat aatatattgc tgatcttaca
    31261 accgctctaa tcgcagcatt cattcctgga gcatctcctc cacttgttag taatcctata
    31321 gttttcattt tttacctcct tggattttat gtcaattttt tattataatc attgttattg
    31381 tattctaatg gacttttttt gtccctatat cactttttaa tcccatcaag actaaaaaaa
    31441 ttaaatgtcc ttaaatgtcc attttgtgat attatatcac aaaacggaca atatttttca
    31501 tattattata atatatttag atttttatat aaaaaatcaa gcttttactt ttatgttatc
    31561 tttaggaagt aactcttcta agttatttat aaattcatca catatacaag ttaatgcccc
    31621 tgtcatttta tatgctttac gtttgccatt tatattttca tccatagggt acaaatatat
    31681 actgtcatta cccggatatt gttttgctat ttctacaata ttattagttg tatcggtgtc
    31741 agacatacta tctattttca aatacaattt tttaccactt tctggcttaa tattttccac
    31801 atttctagtt cttcctgaat tgtaatttct atctacaaag tcagtatcat catttatatc
    31861 ttttatctct ctagctataa gttttgcatt ttcgccttct tttatactta atgttccttt
    31921 tacatatatt atattatctt cattcaaaat gacattgtac ttttgtaata attgaggaaa
    31981 aactactatt tctatagcac catacaaatc ttctaattca agaaatgcca taatttcatt
    32041 tcgttttgtt gttttaatag ttttagttac aatcattcca cccattataa catctgtttc
    32101 attcatttgc aggtatgact cttcttcctc ttttaatgaa tttaattttc cattatccat
    32161 agatgttttt tcttgtaatt ctttttcaaa ttgtgacaaa ggatgtccac ttacatacat
    32221 tcccaagact tctttttcaa ggttaagtct ctctctctct tcgtactctt gccttttagg
    32281 caaactatat atttgttgaa aatcactatc ttcctcacta tctccaaaag catcaaataa
    32341 agaaatttga ccttgaacat ttttctttct atccatagat acactttcta ataaactttc
    32401 ataaccagcc atcaaactag ctctattttc acttatatta tcaaaagctc cacattttat
    32461 tagactttct attactctct tatttgtatc tttttggtct aatcttttaa ctaaatctac
    32521 taaatctaca aataatccat tagattctct ttcagcaatt atattgttta ttatatttac
    32581 gccaacattt tttacagctg ctagaccaaa tcttatattg tcaccttcaa ctgaaaactt
    32641 tgaaaaactt ttgtttatat ctggaggtaa tacatctatt tctagtgctt tacattctct
    32701 tatatactca actaccttat cagtatttcc cattacactg gttatcaatg ctgccataaa
    32761 ttcaactgga taatatgtct ttagataagc tgtctcatag gctaaaaccc catatgcagc
    32821 tgcatgtgat ttattaaatg catatcgagc aaagtctatc atgtcatcaa atattttatt
    32881 ggctatttcc tcttctacac catttctgat acaccctgca atttctatat taccatcttc
    32941 atcaaatttc ccatgaataa aatattgtct ttcttcttcc atcacatcca tctttttctt
    33001 actcatggct cttctaacta agtcacttcg tccgtaacta taaccaccta aatctctaac
    33061 aacctgcata acctgctctt gatacaccaa acaaccatat gtaacttcca ttataggctt
    33121 taatttttca tgtaggtatg ttacatcttt tggattgctt ttatttttta tatatgcagg
    33181 tatagaatcc attggacctg gtctaaatag ggatattccc gctacaatat cttcaaaatt
    33241 gtctggtttt agctgtttca taaaacttct catcccagca ctctccaatt gaaacacccc
    33301 taatgtattc ccagatgaaa gcatttcata tactttcggg tcgtcatagt ccatctttga
    33361 aaaatctatt ttttctgtgt agttttttat aactctattt ttttctatta aatcaagagt
    33421 atctcttata actgtaagag ttcgtagccc aagaaaatcc atctttaaaa gcccaagttc
    33481 ttcaagtgtt gtcatagtaa actgtgttgt gattgcatct tgatgcttgt ataaaggtac
    33541 atactcatct acaggatttt ttgatataac aactcctgct gcatgagtag aagcatgtct
    33601 taacataccc tctatctgtt ttgatatatt tattatttct tttgtttctg ggtcttggtc
    33661 atacaattct ttaagattag gatttgtatc taaagcctta tctattgtca ttcctaaagc
    33721 aaatggtatt tcctttgcta tcttgtcaac tttattgtaa cctatatcca atactctccc
    33781 aacatctctt attgcagctt ttgcacccat tgttccaaaa gttattattt gagctacatg
    33841 gtcatcacca tattttctct ttacataatc tataacttct tctcttctct cataacaaaa
    33901 atctatatct atgtccggca ttgatatacg ttctggattt aaaaaacgct caaataatag
    33961 agaatatttt attgggtcta tgtcagttat cttaagtgta tatgctacta ttgaaccagc
    34021 cgcactacct ctacctggcc ctactatgat attattttct ttagaaaaat ttataaaatc
    34081 ccaaacaatt aaaaaatact ctacataacc cattttttca attacatcta attcataatt
    34141 taatctctct agtatctcat cactaggatt atcatacctc tcttttaatc cattaaaaca
    34201 caactctctt aaataggttt ctggtgtata cccttctgga acatcatact taggaagatg
    34261 tatagtgtta aaatcaaact ccacattaca catatcagct attttcacag tattgtcaat
    34321 agcctctaat gcatatggaa ataattcttc catttcttct ctcgatttta aataaaactc
    34381 atcactacca aatctcattc tatttgggtc atttaatgtt tttcccattt gaatacacat
    34441 aagaacatca tgtattttcg aatcttcttt atttacatag tgaacatcat tagtagcaac
    34501 tagtggtata ccagtctctt ttgatagttt tactaatcca gagtttactt ctttttgctc
    34561 aggtaaattg tgatcttgaa tctccaaaaa gaaattttct tctccaaata tatctctgta
    34621 gtcaaaagca aattgttttg ctttttcata atttctattc attaaagcac gtgctacatc
    34681 tcctgcaagg catgcagaaa gtgctataat ccctttgtta tgttttttaa gttcttccat
    34741 gtcaactcta ggcttatagt aaaaaccttc tacgtatgaa gttgaaacta tttttattaa
    34801 atttttatat ccttccatat tcttagctaa cagaactaaa tgtccttgat atttatcata
    34861 gtttgggtct ttatctctaa gtccacgtgc agctgtatag acttcgcacc ctataatcgg
    34921 ctttattcct tcttttatag ccgttttgta gaaatctata acaccaaaca tacaaccatg
    34981 gtcagttata gctattgagc tcatgtttag ttccttagcc ctttttataa gttttttcac
    35041 cctcgaaaac ccatcaagta aactatactc agtatgtaca tgaagatgag caaaatcttt
    35101 gttcattaaa tcacctcctg ctttataatt ttaccacaaa tatatgtcct aaaacaaaaa
    35161 cagagacttt tatctcaaaa taggaattaa cttcaacata taccattata tgttataaat
    35221 taatgcttat tctgagattg tcccctcaat ttattgtgat gatttttttt tcaaatctgt
    35281 cgcaatttct tctatttttc taagcctatg attgactcca gattttccta ttggtggttc
    35341 taacatctct ccaagttctt tgagagtcat atcctcatac tcgattctaa tcttagctat
    35401 ttcttgtaaa ttttctggca aactgctaat tcctatagtt tcttgtatga gcttaatatt
    35461 ttctacttgt cttactgctg catttactgt tttagaaagg ttagctgtct cacaatttac
    35521 tatcctgttt acattatttc tcatttcttt tactatttta gtattttgaa gacttaaaag
    35581 agcatggtgt cctcctataa tactcaacaa atctgatatt tgctcactct ctttgatata
    35641 aacaacgtga ttattttttc tagccacaat tttactatta aatcctaaag agtttataag
    35701 ttcttttaga gaatctgcaa actcctcatt attagttaca aattccatat gatagttctt
    35761 ttctgggtcg cttatagaac ctccaccaag aaaagctcct cttatgaaag ctctcttaca
    35821 tccttcatgc ttaattaagt tatctgaaat tttgtttata gtaaaaaatc cttctttatt
    35881 ttcaagtata cctaactttt ttaacaacat ttctgaaccc atttcacttg ttaccattaa
    35941 tacataactg ttatttctct ttagcatttg attcttattt accgagattg tagtattgat
    36001 attaaaattc ttctttaata atttaaatac tttacgggct attgaattta actctgttgt
    36061 tatctttaga tttaacttct tatatccaac aatttgtata cttccccctg atttaactag
    36121 agctgacaat tcagctatat tacaacattc attcccagat acaactctcg ctagttcatt
    36181 tttggtttca gttgaaaaag acatatctat cacctattaa ctaatttttc tttaaccttt
    36241 tttttatttc ttgtaaggca acctttatta tctccttttc atcatcatac ctagctaggt
    36301 ctactactct atctagatgg ataaatttag catcaataaa gccttcctct ttttgtggaa
    36361 tagtatccat attctttgct tgcatcaaat accaaaaaac tgttttatga actgctctat
    36421 tttcatccca gttttctttg aatgtatagt gtatttcacc taaatatttc aatatatctg
    36481 cttttactcc agtttcttca ctcacttcac gtaatgctgc ctcttggtta ttttcccctt
    36541 cttctacttt tcccttgggt aacacccaat ctccattgaa cttccttagt aaaagaattg
    36601 tattgccaaa caggactaca ccaccagcac taacctcttc tctcatcgat gttcactcct
    36661 taaaactaac ataatgataa ggatttctac acaatttttt aaaatccttt tttactaact
    36721 tttgttgtaa ttatgattta gggctaactc aataactatg ttagatatat actttgcatc
    36781 atgtcttata taattatttt ttatttcaat taaattcttc tctacagttt ttatacccat
    36841 ctcttttaat ttatcttttt gctttttatc taacaaaact tgttctgctc catcttgttt
    36901 gtataagtca agcatttctt ctggcagtat ctcattattt gcgattacat aatctattaa
    36961 attcttatca gtatgcttta ctatagcatt aacatgctct aatacattgt acccttctgt
    37021 ctcaccgggt tgagtcatta tatttgctat atatactttt ggagctacag acgatttaat
    37081 agcgtctaca atcccctcta caagtaaatt tggtattata ctcgtatata agcttccagg
    37141 gcccataatt ataatgtcag catcgtaaat agatgcaata acatccttta atggtttcac
    37201 atcttttgga tttaaaaaaa ttttatcaat agagcttttt tgaatttttg actcttcagg
    37261 tatactagat tctccattta ttatattgcc attttctaat ttggcaacta aatttacatc
    37321 ttccaaggtt actggcaaaa ctcttcctgt tatagcaaaa atctcactta atttatatac
    37381 agctttttca aagtttccat acaacccatt catagcagcc aaaaacaaat ttccaaaact
    37441 ctgacctttt aaaagccctt ctgtaaacct atattgcata acttcattca ttgttggctc
    37501 tatatttgca agtgctaata gacagtttct tatgtctcct ggtgggagca ttcctaagtc
    37561 ttctctcaat acacctgaac ctccaccatc atcagcaaca gttacaattg cagttatatt
    37621 ttgcgttgtg tgtttaaggc ctcttaaaaa tactgattgc ccagtacctc cacctattac
    37681 aaccacattt ggttctctat tttcaacaat agacctttga aataatttta ctttttcatt
    37741 ttttgctttt ttatatataa ataacgatat aattaatgca atccaaccta aaattcctac
    37801 aataataagt aatttagcca tgtttgcctc cattatcgca acatagagtc tctatgtttc
    37861 tttacaactc tatatccctt attagataaa tcctccgcta taagatttgt tatagtaact
    37921 gacctatgtc ttccacctgt acatccaaca ccaattacta gatgttgttt tccttcctct
    37981 atatattgag gtactaaaaa atgaatcata tctaaaagtt tcacataaaa ttcttcactg
    38041 attttagaat tcataacata atctctaact tctttatcat caccagtttt agctcttaac
    38101 tcttcaacat aatagggatt tggaagaaat cttacatcaa atactaaatc tgcatcagca
    38161 agtataccat gtttaaatcc aaaagatact acagaaatag ttaggtttgg attatcttca
    38221 ccagaagaat atattttctt tatttcttcc ttaaggtctt tgggcttcat gttagttgta
    38281 tcaattatac atgtagataa ttcctttaaa ggttccatta tctttctttc catttttata
    38341 ccttctggaa tctgcatatc ttttgccaat ggatgatttc ttcttgtcat tttatatctc
    38401 tttaacaata catcatcatt acaatccaaa tataccattt catattcata attttctttt
    38461 tctaaataat ttaagctttc atgaagcgct tcaaaaaact ttctccctct tatatctatc
    38521 cctagagcaa ccttatcaat acttgaattt ggttgataac ataattctgc aaatttagtt
    38581 atcaaagcag gaggtagatt atctacacaa taaaatccca tatcctctaa agctctcatt
    38641 gtctcacttt ttccagatcc tgaaagacct gtaactataa caaatttcat tgctaactcc
    38701 tcccttttat cttatgttta ttatattata atgttttcta ctaacgatat atccagatta
    38761 gagtcagata tagtctttat agctagttca aaatcgccaa ctctttctgg acaatgtgca
    38821 tctgagccta ttataaattt attttctagc ccttttatct catttaattg atttaagttc
    38881 aaaaaagaat ggctactgtt tatttcaagt ctagtgtcag tcttttttgc tgtctttgct
    38941 atttcctcta tatacacatc gcctttatct cctggatgag taattataaa aatatcatta
    39001 ttacttatcg catttgctac agcttttgta ttatattctt ttgctttttc agttttaaaa
    39061 atatagttat tacaatgatt taataaactt cttaatgatg ttggagtaga accaaaatga
    39121 tatccagcca taatatagtc aaaatatcta atgaacttat catccatatc tatattgcct
    39181 ttatcgtcta atatgttaca ctccatacct aaaagtatat ttatatcatt gtacttatca
    39241 tttaaataat ctacttcttc tctcatttta agaatatctt ttttctttac accatatgca
    39301 atatgtttat aactatggtc agatattcct attgttttta ttcctttaga aatggccacc
    39361 tttacattat cctcaatagt ccctttgcca tgactatata atgtatgtgt atgataatca
    39421 gccagtattt tcatttgtta atcctctcca agtattttga cttcttcttc caacataacc
    39481 ccaaacttgg catatacagc actttttata acatatatta aatccaaaat atctttagca
    39541 cttgcttctc cttgatttac tacaaatcca caatgcttct cagacacttg tgctcctctt
    39601 aaagtaagac ctctcaatcc agtttcttct attaatttac ctgcaaaata tcctgttggt
    39661 ctcttaaatg tacttcctgc actagcaaaa tttaatggct gtttagttat tcttctcgtc
    39721 gctaaatcat ccattaaact ttttatttca tcataattgc cttcttgtaa ttctaattct
    39781 gctgataaag ctatatatcc atttttcgat attatacttt ttctataccc aaattccatc
    39841 tgtttatttg acaattcaaa tatattgcct tccatatcca tcactcttac tgactttact
    39901 atgtccttca tttcaccacc atatgctcca gcattcatgg ctaatgctcc tcccaatgtc
    39961 ccaggtattc ctgatgcaaa ctcaaaccct tttaattctt gcttttggag agctttacct
    40021 aaaactgata ataaagctcc tgactgagca gtcatcctag tatcatttat ctcataagag
    40081 ttaaaattat cagctaattc tattaccact cctcttattc caccatcttt aattaaaatg
    40141 tttgaaccat ttccaattat taaatacgga atagattctt tttttaccaa cttaagtaca
    40201 ttttttaatt gttcttctgt tctaggtcta actaatatat ctgctggtcc tcctacccta
    40261 aatgaaatat gttttttcat aggttcatcg acttttatat cctctttact taatatattt
    40321 aataaattta tatatatatc ttgattattc attgtatttc ctcccaaatt atactgaact
    40381 ttagctgtca ttattattta aattatatta gtatatagta ttaactatat tcaataatat
    40441 atgattttgc ttatcatatg gattttatat tttaagcttc ttaattacaa actatattca
    40501 ataaatatat aataaagtaa aaaaaaaaaa ataacaacat ataaaagaat ataaataatt
    40561 taaaaaaagc atcaatatca ctgatatcaa tgctttaaaa ggcaatttaa ttcatattat
    40621 ttatctaact atttttgaca tagcaaagat aataaatccc tccaactacc atggaacctc
    40681 caacgatatt tccaagcgtt acaaatacca aattagttat gaattgaacc atagttatat
    40741 ttgctcctag tgccattccc attggtataa aaaacatgtt tgcaacacta tgttggaatc
    40801 cacataatac aaatagcatt attactgtcc aacatgaagc caattttgac attatatctt
    40861 gagatgctgt agacatccat acagctaaaa cgaccagaat attacaaagg attgctttta
    40921 aaaacattga tgctatagtt gaattaacct tagcttctgc cacagctata gcttttgtag
    40981 ctgcatctcc tgtcaatgta gaagaataaa acacaagtgc gactaacaaa attgaaccta
    41041 ctaaatttgc aaaataaacc agtccccagt ttcttaacat ttttcctaat gttatttttt
    41101 tgtccataag tgcaatagcc attaaagtgt ttccagtaaa caactctgct cctgctacta
    41161 ctacaagcat aagacctact ggaaagacca tagcacttaa aaagctagct acccctgggt
    41221 ctatcttgcc aaaagtttga ctaactatca tactccccaa tgccccaaaa cctataaatg
    41281 ctcctccaaa taaacctaat aaaattgcat tttgtgtaga aatgtttgct tttttaatgc
    41341 ctgcacttat agttgcttgt gcagtttcac caggtgtcaa gaatccttta ctcataaatc
    41401 cttccccctt aaaaattata ctttcccttg tctttttatg gcaataatta tataataaca
    41461 atatgatata taataaattt tattaacata aaaaatatac tatatgctta tat
//
LOCUS       DAMKOJ010000031        40343 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000031 DAMKOJ010000000
VERSION     DAMKOJ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.033"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            709..1731
                     /locus_tag="PC592_001751"
     CDS             709..1731
                     /locus_tag="PC592_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055726.1"
                     /translation="MVNWEIKKLIKSKSMFISLGILILILSINIFVKPVLETENYYID
                     KERGRIEDTRNSEEIGNYKFQNKINVLKQLSSQKDMDVFSKKIKSISTNKLYNLIINE
                     YKDVSFWKVFNYRATNSLINVGMLIIIVIIISNIYVDELVFSVRDIILSSKEKKKALN
                     SKIVIAFLVPLTIYSVYLIGIFITTCMQQGMPINGDLEAFRIVDNIATLKCNSSIINY
                     VISNIGIEFLMFEGLAMIALLGSFISKSSITSISFFIFTIVITKIISVIHILPKNLLL
                     AISTVNYYDLIFGFNKIIGNYLGEIIIFKIHIDIVNLLIGVLVAIFIGAMSFCFIIIK
                     SDYISK"
     gene            1744..2631
                     /locus_tag="PC592_001752"
     CDS             1744..2631
                     /locus_tag="PC592_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055727.1"
                     /translation="MNKLEIKNLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQIFYNGEDIFKMDDDYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLKGKYLSSKIEELLDLVGLYDVRDKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKISRNKIIVLSTHIISDIESVAKETIMIKDGKLLMKGTHKE
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSIVLRIVSEDIPIGDNIQPVQ
                     AKFEDVYMFYFDLEDAREA"
     gene            2637..3410
                     /locus_tag="PC592_001753"
     CDS             2637..3410
                     /locus_tag="PC592_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055728.1"
                     /translation="MMYLVKIEMIKILKSKSVWIIWLFLLFFGFVLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKNGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSSLNLTVIQMYIIVILTTIFAS
                     FVFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     IVRYNVPSILIGFSIVISIILMIVLTKITYKNFTSSKRF"
     gene            3522..4247
                     /locus_tag="PC592_001754"
     CDS             3522..4247
                     /locus_tag="PC592_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055729.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLSNIYTAKTRKEGLEVFK
                     NINPDLIILDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDSQNENTDSDNNEEKTISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFANNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLSVKED"
     gene            4251..5654
                     /locus_tag="PC592_001755"
     CDS             4251..5654
                     /locus_tag="PC592_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055730.1"
                     /translation="MKWKITRNFIFTIVFVVISVVIINIISILYVISTDNFLKVVDSR
                     NNPEEFARSFEKDLYEKDGELKLSKIGADKLEKSNSWIQVLNDLGEEVFGVNVPKDTP
                     QKYTPFQMVNNYKYIETEYVNFVLEKYLNKKHLNIIVGIPSRDVSRIILTYSQNNTKK
                     TLNKIIIIILVIDGMVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FSEDEIREYAEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKVNLVGLVRNIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVKIVKKD
                     NIEIIIKDSGVGISKNDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYL
                     NSEIGIGTEIIIEINQN"
     gene            5665..6489
                     /locus_tag="PC592_001756"
     CDS             5665..6489
                     /locus_tag="PC592_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDF4055731.1"
                     /translation="MDFLKKGISGFTIKVLALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMVVEGFCYTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGVIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIVLGIFTVTLLFKATNKII
                     ILFMILVPVPFLVEGGPVWIILGIIFYLCRGKKFSLSICYVLMCIFIFTAMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(6802..7422)
                     /locus_tag="PC592_001757"
     CDS             complement(6802..7422)
                     /locus_tag="PC592_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4055732.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKEAI
                     PGCISCASCFETGKCILNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            7688..8020
                     /locus_tag="PC592_001758"
     CDS             7688..8020
                     /locus_tag="PC592_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055733.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8140..8781)
                     /gene="pcp"
                     /locus_tag="PC592_001759"
     CDS             complement(8140..8781)
                     /gene="pcp"
                     /locus_tag="PC592_001759"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDF4055734.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQKHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTVI
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIK
                     GGFIHIPYMTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(8802..9734)
                     /locus_tag="PC592_001760"
     CDS             complement(8802..9734)
                     /locus_tag="PC592_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDF4055735.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVIFAKYEEPNENFGKEHADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFANSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(9756..10421)
                     /locus_tag="PC592_001761"
     CDS             complement(9756..10421)
                     /locus_tag="PC592_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDF4055736.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGMATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKANIIMAVIALVVATIQFTLYDKKLNNS
                     HKK"
     gene            complement(10971..11444)
                     /locus_tag="PC592_001762"
     CDS             complement(10971..11444)
                     /locus_tag="PC592_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HDF4055737.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNITIVDINNNNKIELSK
                     FDKIIIGSSIYAGSVSKKIRLLCNDNLELLNKKQVGIFLCCGFSEEADKYLKSNFPSS
                     LLESANAIGIFGGEARLEEMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLISLNN"
     gene            complement(11447..11851)
                     /locus_tag="PC592_001763"
     CDS             complement(11447..11851)
                     /locus_tag="PC592_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDF4055738.1"
                     /translation="MKIHNKSSNKKKKYLKISITIFFVFICIIILIVSNLKPENLVVK
                     DINIANIKNGIYTGSADNKLVKATVSVEVNNGKIQNINILKHDNLLGKPAEKITTNII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(11829..12455)
                     /locus_tag="PC592_001764"
     CDS             complement(11829..12455)
                     /locus_tag="PC592_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4055739.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMNNKLYSTVESNIIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNTIFASENTNDTPSNNGIKMLDKCLSTGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLTENFLDILVGGLYNENSQQI"
     regulatory      12803..12846
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            12947..13915
                     /locus_tag="PC592_001765"
     CDS             12947..13915
                     /locus_tag="PC592_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDF4055740.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDRKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNTIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDLIDSVEGVI"
     gene            13917..14480
                     /locus_tag="PC592_001766"
     CDS             13917..14480
                     /locus_tag="PC592_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF4055741.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDLYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQIFTDYAD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            14488..15177
                     /locus_tag="PC592_001767"
     CDS             14488..15177
                     /locus_tag="PC592_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4055742.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLEVLKNVTGKYGVLEVINSGSCFELPKDTLEEIKLIIKEKNIKKLFLESHWSYR
                     NRLEEMREYFEIPVIFKIGVETFDNDFRNNILNKNANFKTPQDVKDYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSNIKRDEELVRWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15304..16032
                     /locus_tag="PC592_001768"
     CDS             15304..16032
                     /locus_tag="PC592_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF4055743.1"
                     /translation="MMFNRGKWNKLDYNELLEYMMSMQDIKHRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISKGNWQEFLEVAEDTYYEEVMLQGMIIGNINSNFEETLYYVKRFI
                     PKINNWSVCDGFCSGLKSMKKYKENMYDILKKYVYSENPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKYEEETFLYIKNNNLDDFTYNKTLQKI
                     IESNRVDLEKKNIIRSMKRKTRRY"
     gene            16046..16720
                     /locus_tag="PC592_001769"
     CDS             16046..16720
                     /locus_tag="PC592_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF4055744.1"
                     /translation="MNNNEERIDKFLELQSKGFRFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNGDLEEEKVKEYEKSKKNTISNRKKVSTKKKVSNEKVL
                     SKSIEQIEFNDTGLKNAKPKKNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNMKP
                     KKVSNKKDIHIDDETIDELKTTRIRIDKEVWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            16746..17582
                     /locus_tag="PC592_001770"
     CDS             16746..17582
                     /locus_tag="PC592_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055745.1"
                     /translation="MNKIVKKSISLMIILTIFIFTLTACEKDEQPDSVDIQVEDKKEI
                     KIDEGNAKVLNIGKSEIINMDEGDKVDTSTKIENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKSVEVYAYEYEAEGKIVYVNLKENTIDIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEEITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            17598..18269
                     /locus_tag="PC592_001771"
     CDS             17598..18269
                     /locus_tag="PC592_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055746.1"
                     /translation="MKVLIVEDNKILLESVAEELRKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18259..19491
                     /locus_tag="PC592_001772"
     CDS             18259..19491
                     /locus_tag="PC592_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055747.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDAGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKINLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIVLELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSVEINVT
                     SDVDIGTTFELSIPKKLK"
     gene            19647..19964
                     /gene="trxA"
                     /locus_tag="PC592_001773"
     CDS             19647..19964
                     /gene="trxA"
                     /locus_tag="PC592_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF4055748.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            19981..20859
                     /locus_tag="PC592_001774"
     CDS             19981..20859
                     /locus_tag="PC592_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF4055749.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SVDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKEKHIEVDG
                     VFVIKDSTSPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21130..21498
                     /locus_tag="PC592_001775"
     CDS             21130..21498
                     /locus_tag="PC592_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF4055750.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIRKCCKRREK"
     gene            21501..21872
                     /locus_tag="PC592_001776"
     CDS             21501..21872
                     /locus_tag="PC592_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HDF4055751.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTTVDAVIVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22016..22471)
                     /locus_tag="PC592_001777"
     CDS             complement(22016..22471)
                     /locus_tag="PC592_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055752.1"
                     /translation="MNINTVQGDSIEVLLRQLGATKISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(22510..23775)
                     /locus_tag="PC592_001778"
     CDS             complement(22510..23775)
                     /locus_tag="PC592_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HDF4055753.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNEKAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            24244..25695
                     /locus_tag="PC592_001779"
     CDS             24244..25695
                     /locus_tag="PC592_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF4055754.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFSNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLENVSEWHRELPEEHLG"
     gene            complement(25905..26333)
                     /locus_tag="PC592_001780"
     CDS             complement(25905..26333)
                     /locus_tag="PC592_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055755.1"
                     /translation="MKTYSIQDLTLDKRNLIKKYSLTLNEDLIWEFKHSKYHTIKYFT
                     HKFAVKESVLALLFNIHKLCYAKIKYFESNFSKYEPYKYSYQHGFVKCEMYDMNFILH
                     KYSNIMIDLRNLQEIKTIEEFRLFCDYLESFEDNLQDLII"
     gene            complement(26735..27196)
                     /locus_tag="PC592_001781"
     CDS             complement(26735..27196)
                     /locus_tag="PC592_001781"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDF4055756.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVST
                     KNIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDNELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(27302..28495)
                     /locus_tag="PC592_001782"
     CDS             complement(27302..28495)
                     /locus_tag="PC592_001782"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDF4055757.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDEGRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINGENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRVPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(28518..29183)
                     /locus_tag="PC592_001783"
     CDS             complement(28518..29183)
                     /locus_tag="PC592_001783"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDF4055758.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTTLLAKNVGDFVNLESDVIGKYVNNFMVNNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(29217..30329)
                     /gene="ribD"
                     /locus_tag="PC592_001784"
     CDS             complement(29217..30329)
                     /gene="ribD"
                     /locus_tag="PC592_001784"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDF4055759.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDDYI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLRDNNIDVTVGTLEEEARDLNEVFFYYIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESKKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNRLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLAINNVTLIDGDILIESDVLN"
     regulatory      complement(30461..30582)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            30771..33254
                     /gene="recQ"
                     /locus_tag="PC592_001785"
     CDS             30771..33254
                     /gene="recQ"
                     /locus_tag="PC592_001785"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDF4055760.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILNEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKAMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFLELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKSLPKRPIVTAFTATASEEVRIDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILNYFGENYMDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFINTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNVLRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFETVIKEYVEKNNINKKINEKNVDLKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPEYMILANKTLKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILEEVNKYVKENDINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHRISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      33343..33454
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            33596..34897
                     /gene="thiC"
                     /locus_tag="PC592_001786"
     CDS             33596..34897
                     /gene="thiC"
                     /locus_tag="PC592_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF4055761.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKVKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            34951..35145
                     /gene="thiS"
                     /locus_tag="PC592_001787"
     CDS             34951..35145
                     /gene="thiS"
                     /locus_tag="PC592_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDF4055762.1"
                     /translation="MKVNGKEIEFEENLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            35138..35941
                     /gene="thiF"
                     /locus_tag="PC592_001788"
     CDS             35138..35941
                     /gene="thiF"
                     /locus_tag="PC592_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HDF4055763.1"
                     /translation="MVKIKIFVNESLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGIKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DVFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            36004..36774
                     /locus_tag="PC592_001789"
     CDS             36004..36774
                     /locus_tag="PC592_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDF4055764.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPIQMA
                     RAFKLAVEGGREAYIAKTGSVSEFANASSPLTGFLGNL"
     gene            36791..37894
                     /gene="thiH"
                     /locus_tag="PC592_001790"
     CDS             36791..37894
                     /gene="thiH"
                     /locus_tag="PC592_001790"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDF4055765.1"
                     /translation="MSFYDVIEKYRNFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEAMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPYIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            37895..38584
                     /locus_tag="PC592_001791"
     CDS             37895..38584
                     /locus_tag="PC592_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF4055766.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELKN
                     LYMKIKTKINCIDFQEQISDESLKTNINQKGCGNKFKVNFIINSNIEFFEKMDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVDEVEYLEKLIRKQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAVMSTIMKSKDIK
                     KTISNYNEKLN"
     gene            38770..40164
                     /gene="yfcC"
                     /locus_tag="PC592_001792"
     CDS             38770..40164
                     /gene="yfcC"
                     /locus_tag="PC592_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDF4055767.1"
                     /translation="MTDSKKKRFVIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLAGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
BASE COUNT        15439 a         4611 c         6356 g        13937 t
ORIGIN      
        1 ataaaatatt ataataaaat aaatttcatt ttcttattag taaaaatttt taagatatat
       61 atttagatat atgctataaa aagctatata aagtatttat aaacaccaaa agatatagag
      121 aattgtctag aataattttt tatatctttt taacatgttt aaaactttta taacttaaca
      181 agaagtatag aaataagcct agagcaaatt ttattaatta acactaaata aaatgtgcaa
      241 aagaattact acttaataat ctttccataa tgaggacaat aagaaccatt ctttagaaac
      301 tcattactta aatctaaaca atgattacag tttagacaaa gataaaattt tcactcaata
      361 aaaataccaa aaataataaa tacaactgta atgataaaca tgcctataga tgttaaaagg
      421 tttattctaa actttatata aatatctgta tttctcatat aactactaaa cttaatctta
      481 ttagaaaaag tatagcaggt atcttataaa aaagataaac taaaagatta caataaaaaa
      541 taaatatatt ttagactatt ttaaaaaaaa ttaaatttaa aagcatattt ttgatgagtt
      601 tcaataaagt aaataattta agctttattt aaggttaaga ttatattgat ataagattta
      661 agttttaata tataagtgta gtcaaaatga tttaggaggc ttagtatatt ggtaaattgg
      721 gaaataaaaa aattgattaa atctaaaagt atgtttatat ctctaggaat attaatatta
      781 atactatcaa tcaacatatt tgtcaaacct gttttagaaa ctgaaaatta ttatatagat
      841 aaagaaagag ggcgtataga agatacgaga aatagtgaag agataggtaa ttataagttt
      901 caaaataaga ttaatgtttt aaaacaactt tcaagtcaaa aagatatgga tgtattttct
      961 aaaaaaatta aatcaatatc aactaacaaa ctttataatt taataattaa tgaatataaa
     1021 gatgttagtt tttggaaggt gttcaactat agagctacaa attcacttat aaatgtagga
     1081 atgttaatta tcattgttat aattatatca aatatttatg tagatgaact ggttttttca
     1141 gtaagagata tcattctatc atcaaaagaa aagaagaagg cattaaactc aaaaatagtt
     1201 attgctttct tagtaccatt aacaatttat tctgtttatt taattggaat attcattaca
     1261 acatgtatgc aacaaggtat gccaattaat ggagatttag aagcttttag aatagtagat
     1321 aacatagcta ctttgaaatg caattcgagc ataataaatt atgtaatatc aaatataggt
     1381 atcgagtttt taatgtttga aggattggct atgatagccc tattaggttc atttataagt
     1441 aaatcttcaa taacatcaat aagttttttt atatttacta tagttataac taagataata
     1501 tcagtaattc acatattacc taaaaattta cttttagcta tttctactgt aaattattat
     1561 gatttgatat tcggatttaa taaaataata ggaaattatt taggagagat tataatattt
     1621 aaaatacaca tagatattgt taatctatta ataggagttt tggtggctat atttataggt
     1681 gctatgtcat tttgttttat aataataaag tcggattata taagtaaata aaggagagtt
     1741 aagatgaata aattagaaat aaaaaatctt tcaaaaatat atggtaaaaa agtagcaaac
     1801 gacaagatta cagtaactct ggaaaatgga gtttatggtc ttttaggacc aaatggagca
     1861 ggaaaatcta ctttaatgaa acaaataaca acattgataa aacctgatga aggtcagata
     1921 ttttataatg gtgaagatat atttaaaatg gatgatgatt atagaaacat tttgggatat
     1981 ttgccacaag aatttggagt ttataaaaat tttacagcaa aagaattttt acagtatatt
     2041 ggagctttaa aaggtttaaa gggaaaatat ttaagtagta agatagaaga actattagat
     2101 ttagtaggac tttatgatgt gagagataag tccataggaa aattttcggg aggtatgaag
     2161 agaagagttg gtatagcaca agttttatta aacgacccta agataatagt ccttgatgag
     2221 ccaacagcag gtcttgaccc acaggaaaga gctagattta gaaatttaat agcaaaaata
     2281 tctagaaata aaataatagt actttctact catataattt ccgatataga atcagttgca
     2341 aaggaaacaa taatgattaa agatggcaaa cttctaatga aaggaacaca caaagaaata
     2401 ttaagccaca tggaaaataa agtatataat gttcaagtta aaaatgaatg tgaagttgat
     2461 gatatacaat ctaaatataa ggttgtaagc attcaaagtg atattgattc aatagtactt
     2521 agaattgttt cagaggatat tccaattgga gataatatac aaccagttca agcaaaattc
     2581 gaggatgtat atatgtttta ttttgacttg gaagatgcaa gggaggcgta gtagaaataa
     2641 tgtatttagt taaaattgaa atgataaaaa tattaaaatc aaagagtgtt tggataattt
     2701 ggttgttttt actatttttt ggatttgttc taattagaaa gtttgatgtt ttagatactt
     2761 atgcagatat attttacaag atagaaggct caatacctct aataggtttg ataatgttta
     2821 taataacttc tggaaattac attaaagaat atgattccaa tatgacaggt ttaataaata
     2881 caactaaaaa tgggaaaaaa tcagtagtat tatcaaaatt agttgctaat ggtttaattt
     2941 tatccattat taatatttct tttatattgt tagtaggaat tagaggcttt agtttttttg
     3001 attttaaaaa tttaaatgaa ccgattcata acttatggta ctttggaaat agtagtttaa
     3061 atcttacagt aatacaaatg tatataattg ttatattgac tactattttt gcttcttttg
     3121 tatttgcaca aataggttta acactttcat ctatatttaa atctgctgta atcccattta
     3181 tactaggtgg actgataatg gcaattccat actttagtgt aggttttata ccagataaag
     3241 ctataaaatt tatgtcagtg actccaaatt ggattatgat gagtcaacaa attgttagat
     3301 ataatgtacc tagtattttg ataggttttt ctatagtaat ctcaattata ttaatgatag
     3361 tgttaaccaa aataacatat aaaaatttta catcaagcaa aagattttaa ctaaagataa
     3421 tagtaatttt atttatatct tagtttaatt taaaataaga tatatgaatt ttagataaaa
     3481 tatatgctaa tatataggta aattattata ggaggttatt tatggaaaac cgtgttttaa
     3541 taatagatga tgaagtagaa atattaaagc ttttagaaac tgtcctaaaa aaagagggtc
     3601 ttagtaatat atatactgca aaaactagaa aagaaggatt agaagtattt aaaaatatta
     3661 atcctgattt gattatatta gacattatgt taccagatgg tgaaggttat gatatttgta
     3721 aagaaataag aaaaacctcc aattctccaa tcatattttt atcagctaaa actgaagaat
     3781 tagataaatt acttggacta gcaattggag gagatgatta tgtcacaaaa ccttttagtc
     3841 ctaaggaagt agcttttagg gttaaagctc atttgagaag attaagttat tttagtgatt
     3901 ctcaaaatga aaatacagat tcagataata atgaagaaaa aactatatca tttggcccgt
     3961 atatattaaa tgaaagtagg gcagaactta taaaagatgg aaagtctata ggattgtctg
     4021 caaaggaatt aaaaatccta tctttatttg caaataatca aaatcagatt ataagtaaag
     4081 aaaaactatg ggataaagtg tggggagaag attatgttgg gtttgacaat actataatgg
     4141 ttcatataag aaaaattagg gaaaaattag aggacaatcc ttcaaaacct gaatatattc
     4201 tgacaataaa aggtcttgga tataaattgt cagtaaagga agattagaat atgaagtgga
     4261 agattactag aaattttata tttacaattg tgtttgtagt catatcagta gtaattataa
     4321 atattatatc tatattgtat gttatttcaa ctgataattt tttaaaagtt gtagattcta
     4381 gaaataatcc tgaagaattt gcacgttctt ttgaaaaaga tttatatgaa aaagatggag
     4441 aacttaaact atccaaaatt ggagctgaca aattagaaaa atcaaattcc tggatacagg
     4501 ttttaaatga tttaggagaa gaggtttttg gagtaaatgt gccaaaggat actccccaaa
     4561 aatatacacc atttcaaatg gtaaataatt acaagtatat agaaacagag tatgttaatt
     4621 ttgtcctaga aaaatattta aacaaaaaac atctaaacat aatagtaggg atacctagta
     4681 gagatgtatc aagaataatt ttaacctact ctcaaaataa cactaaaaaa actttaaata
     4741 aaattatcat tataatacta gtaattgatg gcatggtagc tttaggtgta ggatatttat
     4801 ttagtagaaa acttacaaaa ccaatatcaa gtgtactatg gagtattgag actatggcta
     4861 atggaaatta tagtttatat cttaaggaca gaggtatata tgaagaagtt tttaaaaata
     4921 taaacatgtt agctgatact ttaagagtaa atgaagttga gagaaaagaa aacgaagagt
     4981 tgagagaaga atggctggca aatataacac atgatataaa gacacctcta gcatctatac
     5041 aagggtatgc agagataatt aatgacaaag attatgagtt ttcagaagat gaaatacgag
     5101 agtatgcaga aattatatat aataagtcta agtatataaa agatttagtt gatgatttaa
     5161 atttatctac tcgattaaaa aataatacta tagttttgga caagaaaaaa gtaaatttag
     5221 tcggtttagt cagaaatata ataattgata ttttaaatga caatagatat aaaaatagga
     5281 atattgagtt tgaaagcaat gaagatttaa ttgaagtata tgtagattca atcttattta
     5341 gaagagctat aaccaatctt atatttaatt caatagttca taatagcgaa ggaactttga
     5401 taagtgtaaa aattgtaaaa aaagataata tagaaattat aataaaagat agtggagttg
     5461 gaataagcaa aaatgatttg aaacatattt ttaaaaaata ctataggggt actaatacag
     5521 gtgagatgca taaaggttca ggtcttggta tggctatttc taaagaaata atagagattc
     5581 ataaaggtaa aatttattta aatagtgaaa ttggaatagg tacagaaatt attatagaga
     5641 taaatcaaaa ttaggagata tgatatggat tttttaaaaa aaggaataag tgggtttact
     5701 attaaggtac tagcattaat atttatgact tttgaccata tagcagcatt tatgccacaa
     5761 acaatgcaaa taccaatttg gtttcattgg gtaggcagaa tatcagcacc actatttata
     5821 tttatggttg ttgaaggatt ttgttacact agtaacagaa aaaaatatat aagtagattg
     5881 tatatttggt ctgttattat ggctatagga aatcaaataa ttaataatgt attttcacat
     5941 ccagaaggag ttataattat aaataacatt ttttcaacat tatttttaat agcaatttat
     6001 ttacaagcaa tagagtttat aaagaaattt agaaaagaga aagaaattaa atattttatt
     6061 ataggattat tgatgataat tattcccata gttttaggaa tatttacagt aactttactt
     6121 tttaaagcca ctaataagat tattattcta tttatgatat tggtaccagt accatttttg
     6181 gtagaaggtg ggccagtttg gattatactt gggattattt tttatttgtg tagaggtaaa
     6241 aagttcagtt taagtatttg ttatgtttta atgtgtatat ttatatttac agcaatgtca
     6301 aatggagatt atagtttaaa aaattctatt ttacaaaatt accaatggat gatgattgct
     6361 tctctacctt taatgttgct ttacaatgga gaaaaaggga agagtatgaa gtatttattt
     6421 tatttatact atccaatcca tgtatatata ttgtatatct taggaatata cttaataaat
     6481 ggcttttgat tgtaagtgat atttaataca aaatgaataa tatgaggatt gttttaggtc
     6541 aattaaaatt gttatttaga tgagatttgt agaatattta aaattatgaa cagaaattca
     6601 gttattgtaa ttccaataac attagaatat tatattataa tctatctaga aatatatgat
     6661 aggatatagg gtttgattat taatagaata ataaaacaga ggtttaatat aaaattcata
     6721 cctctgtttt attgcttttt atcctatatt tatgcttatt tatagattag tgttttaatt
     6781 aatattactt cattttttta tttattttat aaaattagtc ataattgttt cttcatattg
     6841 tggttcttta attcccgctt ttttacctgc tgatatacat ttaagaagcc atgccatatt
     6901 ttctcctaga gttcgcatag tttgtaatcc ttcttcatct ttcataacat cctctggagt
     6961 aaagccatgt acctgattcc aatactgtga tgatactata ggcatattgc tgattgaaaa
     7021 atatttattt agttggtcaa atgttgcact tgcaccacca cgtctacatg acacaactga
     7081 agcacctaat tttgtagcca tacgacttcc agctatgaaa aatagacggt caagaaatga
     7141 agttaattga ccagttgcac tagaaaagta aacaggagaa ccaataataa taccatcaat
     7201 attatcgaga tcttcaatca attcattaac tttatcattt agaatacatt ttccagtttc
     7261 aaaacaggat gcgcaactaa tacatcctgg gattgcttct ttacctaaat acagtatttc
     7321 tgttttaata tcgtgtttac tcaatacttt agtaatctca ttcagtgctg tataagtaca
     7381 tccatattgg tttgggctac cgtttatcaa taaaactttc attataaatt tcctccaatg
     7441 aattttattt aatagatttt ttaagagata ttatttttta taaaatagga ttttcatgaa
     7501 tattatcaat ttatatagaa atatctaatc ttagaatcct atttaaaata actccttttt
     7561 tagtaaatac acctcctatt ataaaattga ctttcaatta ttcttacact ataattttat
     7621 tataaattat tctaaaaaca agtacgcaca tttttgttca atactaacca aaaggagagt
     7681 gtaatatatg agtatagact gtatatcaaa tacagattta agtgaaacag gatttagtta
     7741 tacactttca ctgattagtg gtaaatataa aatgataatt ctttactgtc ttgtagaatt
     7801 tgaagttgta agatataatg cattaaaacg ttatataaat actatctcct ataaaacttt
     7861 gagtttatca ttaaaagaat tagaagcaga taacttgatt attcgtactg aatatcctca
     7921 aatacctcct aaggtagaat atagcttatc agaaagggga aaatctctga ttccaatttt
     7981 agatgcaatg tgtgagtggg gagagaggaa tagaccttaa ttttgtatct gtagatacta
     8041 taaaaagact gtgagtaaaa ttgtttgaat aatctactca cagtctatat ttaaattaat
     8101 agttagtatt tttaatttat aaaaatacta aaaaatttat tatgaaattt cgccaccaat
     8161 ttcctttaca tcttccttgt atataataca agcttctata gccaattcta aaccttttac
     8221 tatttcttct aaagacataa atggtgtatt ttttttatct attacttgtg aagtcatata
     8281 tgggatgtgt ataaatccac cttttatatt aggatatttc ttgtctatca tataaaggat
     8341 tccatacatc acatgattac aaacaaatgt ccctgcagtg tttgaaacac tagctggaat
     8401 tttattttca ttcatatgtt ttaccatggc ttttacaggt aattttgaaa aatatgcagg
     8461 ttcaccatcc tcttttataa cagtatctat aacctggtta ccttcattat cttttattct
     8521 aaaatcatct atatttatag caactctctc aggtgtaatg tcaaatctac ctccagcttg
     8581 tccaaccgat attactatat ctggattgtg cttttgaata gctttatcta tagcttcaac
     8641 agactttgtc ataactgttg gtatagttat ctttatgatt tctgcaccat ttatattatt
     8701 attgaccctt tcaactgctt cttgagccgg gtttattggt tctccaccaa atgggtcaaa
     8761 tcctgttaac aaaattttca ttattttacc tcctaattat attaaaatcc taaaaaatac
     8821 attactaata tgtgggctat aattaatacc aaagcaactg gagcttgata ttttataaca
     8881 atataatcat ttttacattc tagtaaggct gctggaacta tattaaaatt agcagccatt
     8941 ggagtaagta gagttccaca atatcctgct gttaatgcta atgctccaat tatagcagga
     9001 tttccaccct gagacaatac aaaaggaata ccaattcctg ccgttatgac tgaaaatgca
     9061 gcaaatgcat ttcccattat catggtaaat ataaccatac ctaatacata agctataaca
     9121 ccaaataatc tgctatcagc agggactaca ccagatatca tggttgaaat aacttcgccg
     9181 actccagcct gagtaaacaa agctcccaat gcaactaaaa gttgtggtaa catactagca
     9241 ggacccattt gttgaagtaa tcttgaacca tcttgaactg atgtagcagg ttttgcctta
     9301 gttattataa gggctgatat taatgcaatt attgaaccta cacctattgc aaattgtgaa
     9361 gaattagcaa aattagaaag gctcatagcc acaactactg cagcaaatgc taatattaat
     9421 gatggtataa atattttgtt tttaagttta tctgcatgtt cttttccaaa attctcattt
     9481 ggttcttcat actttgcaaa tataacttgt ttagaaagtg ttaataaact agataatatt
     9541 aatattattc cgattatatt agctggaatt aatctaccaa atatgaatgg caatgatata
     9601 agtatccaaa ataatgatgt accatatttt ttattgttgt ttatggtagt aaaagactta
     9661 tatgctatga caatcattaa aaatcccatt agtgcgtaaa aaatttctaa tgatatattt
     9721 ataaaatttt gcatttttat tcctcctaaa taaatctatt ttttatgact attatttaac
     9781 tttttgtcat ataaggtaaa ctggatggta gctactacaa gtgctattac tgccataata
     9841 atattagctt ttacaatatt aagaccagtt acattgtatc caaattgagt gagagtagat
     9901 gctataagta acactccact actacctgca aataggtttt gaccataaaa gtttccatag
     9961 ttttctgacg cggcagacaa tgcttttatg gcttcttcat ccgattcttt tagttcatca
    10021 ctattactta aaccagcagc ttgtgccata ggattaacaa gtggtcttac aaattgagga
    10081 tgcccactca ttctgattga tagagcacca gctatttgtc tagctatcat gtatatagta
    10141 agtacttttc ctgttgtgag tctttttaat ttttctatta aagaaacagc tctttgtttt
    10201 aaaccatatc tttctaatac accgattact ggcaaagtta atatgaataa tgatacacct
    10261 ctgtttgaga caaaagaatc tcctaagatt gtaaagattt gattaaaatc taatcctgca
    10321 acaattcctg ttgccattcc tgctaataat acagtaaata atgtgtcaat tttaagtata
    10381 aatccaatta caactatcaa tataccgatt agttttatca taaattgttc tccttccatt
    10441 tctatatgtt ttaatttaaa tttatttaat ggataaagtt aaactctttt tatagtattt
    10501 gcgttaatag gactattatt ataaaattta ataaaaaata gggaagatgt tttaaatcgt
    10561 caaagtaaat aagcgttatg taaagaaatt ttgaataagt aagattatat tttaatctaa
    10621 tatgaattga ttttgatatg tttataattt aagtatgtgg taatatttaa aatagtagtt
    10681 ttaaattaaa tattatatta taaaaagaga atatctcaaa atagagagaa gtctattttt
    10741 taatgttgaa atgataaaaa tatatttgat tccatgcaaa aaggtagtgt ccaatgaact
    10801 aaaaagttca tcagatacta cctttttatt atgattaaca aaacatatat tgagtactag
    10861 ttttattaga tttcattaag aaaaataaaa ttttaataaa gtctaaagac tattttgagc
    10921 aatattactt agaaataaaa gagtttatca tagagataat tagttttatt ttagttatta
    10981 agacttatta aaaaattatc tatattatcc tgtgatattc taaaactgtc ataattacct
    11041 tttgaaacag ctttcataat aagtttatct aaaaatttca tttcttccaa tcgagcttca
    11101 ccaccaaaaa ttccaatcgc atttgcactt tctaacaagg atgatggaaa atttgatttt
    11161 aagtatttat ctgcttcttc agaaaagcca cagcaaagga aaataccaac ttgttttttg
    11221 tttaataact ctaaattatc attacatagt aatcgtattt tttttgaaac tgaaccagca
    11281 tatatagagc ttccaataat aattttatca aattttgata attcaatttt gttattatta
    11341 ttaatatcaa caatagtgat attatctgag agtttatttt ttagtatatt tgcacagtct
    11401 tttgtacaac catatttact tgaatatata ataatagtat tcataattat tctccttttc
    11461 ttaaagcatt ttctacagct tttcgtatag tattactgct ataagttgca gaagttatag
    11521 catccacatc taaagactgt tgtttaataa tatttgttgt aatcttttca gcaggtttac
    11581 ctaaaagatt gtcgtgtttt aggatgttaa tattttggat tttaccatta ttaacttcaa
    11641 cagacacagt agcttttact agtttattat cagcacttcc agtataaatg ccatttttaa
    11701 tattagcaat atttatatct ttaactacta aattttctgg ttttaagttg cttacaatta
    11761 aaataataat acatataaat acaaagaata tagtaataga tattttgaga tattttttct
    11821 ttttattact agatttgttg tgaattttca ttgtaaagtc ctcccactaa aatatctaag
    11881 aaattttctg taagttgaga aaaattatgt aaagaatata atttattttc aacaacacat
    11941 aaaacgaatc ctaacaatgc acttataagc atccatgagc ttttatctat atttttttta
    12001 aatattccct gttcaatccc agtggaaagg catttatcaa gcatttttat accattattg
    12061 ctaggcgtat catttgtatt ttcagatgca aatatagtat tcattctact atgcatgata
    12121 gcttttgcca tctctggttc actagaaaga gtttttataa agctagtcat aatttctatg
    12181 atttgtttat ctattggtag cgacgaacaa ttattcataa tgtcaataat attactttct
    12241 actgtgctat aaagtttatt gttcatatcg ctgataatct ctgctttgtc tttgtagtaa
    12301 agataaattg tagttggaga atattctatt tttgtagcaa tttttcttat tgataaattt
    12361 tcatatccat gttgatttat aatttcgatg ctagcatcca taatcttttt cttcatttct
    12421 tctttttcat ttttacgtct ttctttaata ctcatttaat cacctcttca cttaacagtg
    12481 ttaatttaat ttacactgtt attgtataat ttaagtttaa tactgtcaat aaattattaa
    12541 ataatataag ttaatatatt tttatggcta ataaattaat gttattaatt gtaatattta
    12601 agatattatt gtataataat aatcggttta aatgcgccac attttattaa agttggttaa
    12661 taattttaaa taaactttaa taaaatacat taaaatataa taaattcttc tatgctataa
    12721 aatttatttt atagctatta aatcggatgt ttaaaaattt tttaagagtc tatagtaagg
    12781 aatctaaaat tataatttta catctgtact tgttcgagaa ctccaagtat aaaaaactaa
    12841 ggaattatat agtggcagta tataattaat acccttagac acaccttttt gaaagtggaa
    12901 aaaagatgtg tagttctcct cgaccacaaa tcaaggagga taaaaaatgg aaaaaagaaa
    12961 agtaataatc gattgtgacc caggaattga tgattctttg gcaattcttc tggctttaaa
    13021 ctcaccagag ctagaagtaa ttggaattac cacgtgctgt ggaaatgttc cagcaaatat
    13081 aggtgcagaa aatgcactaa aaacacttca aatgtgttct tcactaaata ttccagtata
    13141 tataggagaa gaagcaccac taaaaagaaa acttgtaaca gctcaagata cacatggaga
    13201 agatggtatt ggagaaaact tttatcaaaa agttgtagga gctaaagcaa aaaatggagc
    13261 agtggatttt ataataaata ctttacataa tcatgaaaaa gtatcaataa tagcacttgc
    13321 accacttaca aacatagcta aagcacttat taaagatagg aaagcatttg aaaatctcga
    13381 tgagtttgta tctatgggag gagcatttag gattcatgga aattgctctc cagtagcaga
    13441 gtttaactat tgggtagacc cacatggagc agattatgtt tacaagaatt tatctaaaaa
    13501 aatccatatg gtaggtttag atgtaaccag aaaaattgta cttactccta atactattga
    13561 gtttataaat agacttgata agaaaatggc aaagtatata actgaaataa ctagattcta
    13621 tattgatttc cattgggaac aggagggaat aattggctgt gtgataaatg accctttagc
    13681 agtagcgtat tttatagata gaagtatatg taaaggattt gaatcatatg tagaagttgt
    13741 agaagacggg atagctatgg gtcagtctat agtagattct ttcaatttct ataaaaaaaa
    13801 tcctaatgca attgttctaa atgaagttga tgagaagaag tttatgtaca tgtttttaaa
    13861 gaggcttttt aaaggttatg aagaccttat agactctgtg gaaggagtga tatagtgtga
    13921 aaagaaaaat atgtgtaaaa actattacac ttatagcttt tggtatttcc ataaatataa
    13981 taggcgcttt tatagctatg ggattaagat tacctgtata tttagattca ataggaacta
    14041 taatgatagc ttcactttta ggacctaaat acgctgttgt tacaggtgtg tttggaagtt
    14101 taataagtgg aattacgttt gatttgtatt ctctatattt tgcaccagtt caaatatcaa
    14161 caggattact tgctggaata gcatttaaaa agaatttttt aaggggttta aaaactccac
    14221 taggagtact cttatttgcc attccaacgt ctataataag ttcaataatt tcagcatttt
    14281 tatttggagg tatgacatct tcgggttcat cctatatagt acaaatcttg aaagtattag
    14341 gattgggaga tgtttttagt gtgtttgtaa cccaaatatt tactgattat gcagataagt
    14401 tgttagcagt tgttttagtg aatttaggac taaatgcagt tccaaaaact ttaaaggtgt
    14461 cattgactgg aggaaaatag atataaaatg gatagatata gtgaaataac aaataaaaat
    14521 caaagagaaa ttgttctgct taaaggattt ccttgtatat ggggaaagtg ttctttttgt
    14581 gattatatag atgataattc taatttagaa gaagagatga ataaattaaa tctagaggtt
    14641 ttaaaaaatg taactggaaa atatggagtt cttgaggtca taaattctgg aagttgtttt
    14701 gaattaccta aggatacttt agaagaaata aagcttatta taaaagagaa gaatataaaa
    14761 aaattatttt tagaaagtca ttggtcttac agaaataggc ttgaggaaat gagagagtat
    14821 tttgaaattc ctgtgatatt taaaattgga gttgaaacct ttgacaatga ctttagaaat
    14881 aatattttaa ataaaaatgc aaattttaag actccacaag atgtaaaaga ctattttgat
    14941 tcaccttgta ttatggttgg aataaaagga caaacaaaag agatgataga taaagatata
    15001 gagattatct taaatacttt tgaaaaagcg acagtgaatg tttttataaa taattcttct
    15061 aatataaaaa gagatgaaga gttagtgaga tggtttgtta gtaagtataa attcttggat
    15121 gaaaatccaa atatagaagt tttatacaat aatacagact ttggtgtagg agattagcat
    15181 taatttagtt taaatttaaa attgaaaaat ttcttatgtt tttgaaaaag cttctaatag
    15241 ttagaagctt tttttgtaga gttttatgtt acaataagaa aaaaggaatt aaggagcaaa
    15301 taaatgatgt ttaatagggg aaaatggaat aaattggatt ataatgaact tttagaatat
    15361 atgatgtcta tgcaagatat aaaacataga gattttaata aaaagcttat acctggaaca
    15421 gaaaatataa taggtattag agttcctaat ttgagaaagt tatcaaaaga aataagcaaa
    15481 gggaattggc aggaattttt agaagtagca gaggatacat actatgaaga agttatgcta
    15541 caagggatga taattggcaa tataaatagt aattttgaag aaactttata ctatgtaaaa
    15601 agatttatac ctaaaattaa taattggtca gtttgtgatg gattttgttc tggtttaaag
    15661 tctatgaaga aatataaaga aaacatgtat gatatactta aaaaatatgt ttattcagag
    15721 aatccatggg aaattagatt tgcattagtt atgtttttaa tatattatgt tgatgataaa
    15781 catattaaag aaatatttga atactgtaat aatatacaaa gtgaagaata ttatgttaaa
    15841 atgggtatgg catggttgct atcaatttgt tttattaaat atgaagaaga aacttttctt
    15901 tatataaaaa ataacaattt agatgatttt acttataata aaacgctaca aaaaataatt
    15961 gaatcaaata gagtagattt agaaaagaag aatataataa gaagtatgaa aagaaagaca
    16021 agaagatatt gacggaggaa tattaatgaa taacaatgaa gaaagaattg acaaattttt
    16081 agaacttcaa agcaaaggct ttagatttgc agagatagct caaaatctaa agattagtca
    16141 aagtacttta agaacttttt taaataaaaa agggtataag tcagaaaaag gtaaatacat
    16201 attaaaagac gaattaaatt ataataaaag tttagataat ggagacttgg aagaagaaaa
    16261 agttaaagag tatgaaaaaa gtaaaaagaa tactataagt aatagaaaaa aagtaagcac
    16321 caaaaaaaag gtttctaatg aaaaggtttt aagtaaaagt attgaacaaa ttgagtttaa
    16381 tgatacaggc ttaaaaaatg caaagccaaa aaaaaatgtt aagcctaaga aagatagaaa
    16441 aataaatata actcaagaag atttagataa gctttgtgaa gtatatgatt ggtacttaga
    16501 agtaaaagat tacaatatga agcctaaaaa agtatctaat aaaaaagata tacatataga
    16561 tgatgaaacc atagatgaat taaaaacaac aagaatacgt atagataagg aagtatggaa
    16621 tgattttgaa agattatgta gtaattcaaa ttttgaaaaa catcaaatac ttacacaagc
    16681 attgaaagaa tttatgaaaa aatataaaaa tctactataa aatactacta tatgaggtgc
    16741 ttaatatgaa taaaatagta aaaaaatcaa tttctttaat gattatatta acaatattta
    16801 tttttacgtt gacagcatgt gaaaaagatg aacaacctga ttcagttgat attcaagtag
    16861 aagataaaaa agagataaaa atagatgagg gaaatgcaaa agtattgaat ataggaaaat
    16921 cagaaattat aaatatggat gaaggtgata aagtagatac atccacaaag atagaaaata
    16981 actcaacatt taatatatcc aatgttgaat tgatatataa tgaatatgat gagaataaaa
    17041 aaattatatc ttcagatagt aaggctttgt tggacatgac tttaatgcct ggaaaagttg
    17101 cttatataga atgtgggcat aaaacctttg taaagagtgt agaagtttat gcatatgaat
    17161 atgaggcaga gggtaaaatt gtgtatgtta atttaaaaga aaatactatt gatataagaa
    17221 ataataatat taagctagaa aatagtagtc agtatgaggt actatctaca tcagaactta
    17281 aaaaagtaaa tgaatcaaat gaggaaatta cgtatcaagt aaaagtaaaa aattcatcat
    17341 caaaagattt aggaaatatt attcttaaga cagcagaagt taatgaaaat ggagaatatt
    17401 taacagtaaa tcgtgtacca tcatataaga ttttgaagcc ttcagaagag acagatatag
    17461 atatattgtg ctccacaaag gcaaaaagtg ttgaaatagt aggatataca tatgatgata
    17521 taaaggaaaa agccaatgtg gatattgact taaaatctca taaagttaag atagacaaat
    17581 aaaggtaggg gatacttatg aaggttttaa tagttgaaga caataagata cttctagaaa
    17641 gtgtagcaga agagcttaga aagcattttg aaactgaaaa gtgtgaagat ggagaagaag
    17701 ctttatactt agtaaatcaa aatatatatg atttagttat tttagactta atgcttccta
    17761 atataaatgg atttgatatc ctaaagaaaa tgagagttaa taatatagat acacctgtac
    17821 ttatattgac agcaaaagaa acattagatg acaaagtgga agcatttact ataggagcta
    17881 atgattattt aactaaacct ttttatatgg aagagttagt agcaagggtg tatgctatat
    17941 taaggactaa tggaaagata aaagaaagaa acggattaga atttaaatct ttatatttag
    18001 atacactaga aaaaagagtg tatattgaaa aagaagaaat aaaacttcaa aacaaacagt
    18061 ttaacttgct tgagtatttt gtactaaata aaggttcaat tttattaaaa gagcagattt
    18121 atgatagaat atggggaatt gattcagatg caactattga aatagtggaa gtatatgtaa
    18181 gtaatctaag aaaaaagctc agtaaatatg gatatgataa atatattaaa actaaacgta
    18241 aggtaggata tatattcgat gataaataag aatgtattta ctagtactaa aaatcatcta
    18301 ataaaaatgt atattattgt agtaggtagt tttttaataa tcttttctat atttatatat
    18361 tcatatttta ggggacttac atatagtgga attgatagtg agataaatga tgagcttgaa
    18421 tatatagttt ctcaatttaa aagaacttca tttttgaacc caataagact caaagaccct
    18481 aaagatatgg tgtatgtata tgaagatgga aggataagtt actatactca aaatgaatat
    18541 tttgatgagt tgcttccaga tagaagacta gataaaaaaa attcgttttt taaatacaca
    18601 gaaaatggat atactttcag agaattaaat gtagatgcag gtagatacca aatacagata
    18661 attagaaata tagattctga gatgaattct ttaagacagc ttacatctgt tcttataatt
    18721 ggaatattaa tttctgtaat aattacttac tttgtagctg tatatctcac tagaaaagct
    18781 ttaattccaa tagaaacagc atggaaaaat caagctaagt ttatacaaga tgcttctcat
    18841 gaattaagaa caccaataac aatagtttca tcaaaattag aaagtatgtt aaaatcccca
    18901 gaaagtacag taaatgatga agttgaaaca atagctactg caatgaagga aactaggaga
    18961 cttaaaaaaa tgataactga tttattgtct cttactaaag aggattctat tgttaaaatt
    19021 aatttagaag aaatagactt agaaaagtta ttggaagaaa tatcagaaga ctatattgac
    19081 atagctgaat ttcaggaaaa aagattcgta tttaattcta aactgaagaa taaagttata
    19141 ataacagata aaaataaatt aagacagctt atattgattt ttattgataa tgcctttaaa
    19201 tatacaaaat tgggagatga gatagtatta gaattaaaag aagatataga agatgaggta
    19261 actttgctta taagtgatac tggtataggt ataaaaaaag aagaaatacc tcttatattt
    19321 gatagatttt ttagaagtga aaatgtaaga aataaagatt tagaaggttc tggaatagga
    19381 ctttcaatag ctcgaatgat tagcttaaac ttgtctgttg agataaatgt aacttctgat
    19441 gtagatattg gaactacatt tgaattatca ataccaaaaa agttaaaata ataaaaatat
    19501 aaaaagttgt ttttagaaat aaagaatggg tatactaatt agtataaaat aaaaaataaa
    19561 aagaccttat aaaagtaaaa ttatatttat aaatttcata gtataattat atagggataa
    19621 taaagtttaa taggaggatt taaaaaatgg caaaagttat aaatacatct gaatttagaa
    19681 gtagtgttga aggtagtaag ggagtagttg tagttgattt ctttgcaact tggtgtggac
    19741 cttgtaacat gttgggacct gtatttgcag aattaggtga agagatgaaa gataaagcta
    19801 gatttgtaaa agttgatata gatgagagct tagaaatagc tcaacaattc aatgtgtcta
    19861 cagtaccaac tatgattata tttaaagatg gaaaaccagt agaaacttta attggattca
    19921 tgccaaagaa caaaattgaa atgcaagtaa aatcatattt ataaaaaatg ggtgagtatt
    19981 atgagatatg atatagctat aattggtagt ggtccagctg gattgtctgc tgctataaat
    20041 gcaaaaataa gaaataaaac aattatcatg tttggtaatg ataatttaag taataagctt
    20101 gttaaagccc cttcagtaga taattattta ggtttttatg atataagtgg tgatgaatta
    20161 aaagataagt ttaaatcaca tatagatagt atggatattt caattgaaaa taaaagaata
    20221 aataatattt atgctatggg agaatacttt acaataatgt ctggaaatga tatgtatgag
    20281 gctactactg taatccttgc aactggagta gagtatacta gaccaatcaa gggtgaagaa
    20341 gaatttctag gaagaggtgt aggctattgt gctacatgtg atgcaccact ttatagaaat
    20401 aaaaaagtag cagttatagg atataatgaa gaatctaaag aagaagcaaa ttttttaagt
    20461 gaactcactt caaagactta ttttatacct atgtacaaaa aagataatct tatgagaagt
    20521 tcagataacc tagatgattc tattgaagtc atacatgaca gaccagtaca aatagatgga
    20581 gataaacttg taaacaaagt atcttttaaa gaaaaacaca ttgaagttga tggagtattc
    20641 gttataaaag atagtacatc tccaagtgcc ttggttcctg gaatagaaat tgatggcatt
    20701 catattaaag ttgacaataa tatgaaaact agtatagatg gatgttttgc tgctggagat
    20761 tgtgttggaa aaccatattc ttatataaaa gcagctggcc aagggcaaat agcagcttta
    20821 aatgctgttt actatttaga taaattaaag agggcttaat atttatattg attaactttt
    20881 taaagatatt tataaaaaac tgtcttgaaa taattttatt atttcaagac agttttttat
    20941 ttgtaaatta ctattaaaag tattttaaaa tctatatgta attactttta ttaaaaaaaa
    21001 ttaaaagtta tattagaaag aattagaatt atttataata tataccaaaa tttaaaaata
    21061 atggttgaaa aatctaatta agagtactat aatttaatta agtaattact taatcaaaac
    21121 gaggtactta tggaaaactt ggttaaaata tttaaagcat tgagtgatga aactagactt
    21181 aacatactta tattagtatc caagagaaat atatgtcaaa aggggatttc taaatatcta
    21241 gggatttcag attctgctgt ttcacaacat ataaaaatat taaaagatgt tgggataata
    21301 acaggatata aagaaggata ctatgtttta tatcatatta ataaagaatc atttaatata
    21361 tgtgtagatt ttataaattc tatgttaagt aattctagtg aaagctttat agatgtattt
    21421 gatgtaaata caatacatct aggatgcagt aaagaatgta aatctataag aaaatgttgt
    21481 aagagaaggg agaaataata atgaaagtat gtataccagt agaagagaat aagggattgg
    21541 atagcaaacc atatgggcat tttggttctg ctccaatttt tgttgtgtgt gatttagaaa
    21601 gtggagaagt taagtcttta gataatggcg atttagatca tgaacatgga aaatgccaac
    21661 cattaaaagc attgtcaggt acaactgtag atgcagtaat agttggagga ataggacaag
    21721 gagctataat taaattaaat ggaatgggaa taaaagttta cagagccgaa ggcgatacta
    21781 taagtgctaa tttagaccta cttaaaaatg gaaaattagt agagtttcca tcagaccata
    21841 cttgttcaca tgatggatgt ggacatcatt aaaaaaaata gctgatgaaa catatgcttc
    21901 atcagctatt ttttctttta ataaatacga ttttattctt ttaaaaccaa aatttagatt
    21961 tttatgtttt ttgtaatatc ctcgataaca tctcgagttt ataagtttac tacttttaga
    22021 tttttttcgt atgtttttct atatagtcaa tatcatttaa tatgtcatta agctctttat
    22081 taagtgtttt taaatcatca ccatctacat tgtagtttaa aaatagttct tctacattat
    22141 caatgataga attaactttt ctagtaactt caacaaatgt tttaaagtta ctactatttt
    22201 tagcatttag aaattttttt aaatcctttg atataaatga tactatttca tattcgtcat
    22261 taaatagacc tctaccaata ggatatggtt caattctctg taaaaaatat tggtctttag
    22321 cattaatatt ataagtataa gatatttccc aaccgtctcc taaatcaaac ttaataaaat
    22381 ataatgtact acttactttt gatatttttg tagcaccaag ttgtcttaaa agaacttcaa
    22441 tcgaatcacc ttgaacagta ttaatattca tatatacaca tcccctttag tattattata
    22501 ctatattttt taaaatttta taattaaata aacagtagat ataataatag atataatcat
    22561 aagtggaaaa cctattttga aatactcttt aaaagagata ggatgcccgt gtttattacc
    22621 tatacctgct agtacaacat tagcagatgc tcctattagt gttccatttc ctccaagaca
    22681 agctccaaga gatgttgccc accatagtgg cattacatca ataccttcag cttgcatagt
    22741 taaaataagt ggaattagtg ttgcaacaaa tggaatatta tctaagaaag aagagactat
    22801 cgctgataac catagtatca acaacattgt aaatacaaga tgtccttctg taagtccaat
    22861 caatgcctga gccaatttat ttattatacc aacttctact aatccaccaa ctactacaaa
    22921 taatcccata aagaataaaa ttgtagacca ttcaatacct gccataattt catctacatc
    22981 ctgttttcct attagaagca ttatagatgc tcctgtcagt gctacaacag aagagtctat
    23041 atggattgta ctgtgaaaca taaaaccaaa aagtatgaat gctattaata taagactttt
    23101 tataagtaga ggtttatctt taacagattt tttttcatcg agtttcaata ttgcgttttt
    23161 agctttttca tttacaacaa gttcttttcc ataaataaat ctaaagcata ttatagttat
    23221 agcaagtatt actataacag caggacctaa atttattaca aaatccataa aactaagatt
    23281 ggcagcacta ccaatcataa tatttggagg gtctcctata agagtagctg ttcctcctat
    23341 atttgaagct aaaatctgtg ttattaaaaa tggaacagga ttaagtccta atatttgtgt
    23401 aataactata gtcattggtc caataagtaa gacagttgta acattatcta atacagctga
    23461 taaaatagct gttataatag caaaacaaat cattatcttc catgggtcac ctttagcttt
    23521 ctttgcagtc cagatagcta tgtattcaaa taatcctgag tttttgacaa cagctacaaa
    23581 tagcatcata ccaactaata caccaatagt gttgaaatct atatggctta atccttcatc
    23641 aagcgtaagt atattgaata ttatcattaa tagtgcacca ccaacagctg ctacggatct
    23701 gtttaccttt tctgtaataa tagctgccat aactattaaa aatatacata tagctattat
    23761 ttgttgaaat tccataatat aagtacctcc atttgtatta ttttgagcct aatgctagta
    23821 ctatatatag tattactttt ttattgtttt ttcaatggat gtatgaaagt atattattta
    23881 acaaagtttt tgaaaaattg acagaattta aagaaaattt ttgttattta aataaatttt
    23941 aaaatcattc cattgataat aatattaaac gacaaacgaa aaaatatacc cttcaaacta
    24001 gaatttattg taacaaataa caattataaa atattaaata tatctatatt ataaaaacag
    24061 taaaaaaagg tttaatctga atataaaact gcaatatatt aaaaaaatta ttcattttaa
    24121 gccttgtaat ttgattttat aaatattata attaaattaa tgaattttta acaaggaatt
    24181 attcattttt ttgattttaa gatttattga gaaaacaaaa ctaaataggg ggtaattaat
    24241 ctaatggatt ttttcaatgg tattttaact agtatcaata atgcagtagt atttgtaaac
    24301 aattacttat ggtcgtatat cctaattata atgttagttg taattggtat ttactttact
    24361 atcaaaacaa attttgtaca attcagatat tttatagaaa tgtttagact tctgggtgat
    24421 ggtacagcaa ataaaaatgc aaaaaaggaa ggaaaaatat cttcattcca agcattttgt
    24481 ataagtacat cttcaagagt tggaactgga aatatagctg gaatagcaat tgcagttgta
    24541 gcaggaggtc ctggtgctgt attttggatg tggcttatag cattgattgg ttctgcatca
    24601 agctttgttg agagtacatt agctcaaatt tataaagtta aagatggtca agcttttaga
    24661 ggtggaccag cgtattatat ggaacaaggt ctaaataaaa aatggatggg tattttattc
    24721 tcaatactta taactatatg ttacggtttt gtatttaatg cagttcaagc aaatactgtt
    24781 tcacttgcat ttagtaatgc atttggaata agtaaaatgg ccatgggaat aggtcttgga
    24841 attttaactg caatagttat ttttggtgga gtgcatagag ttgcaaaagt ctctgaaata
    24901 atagttcctg tatttgcagg attatatata ttagttgctt tagctatagt tgtaatgaat
    24961 ataacagaga taccaagtgt tatagcgttg atagtggaaa gtgcatttga ttttaaagga
    25021 atggcaattg gtacatttat gggagttgta atgactggag tgaagagagg tctattttct
    25081 aatgaagcag gtatgggtag tgctcctaat gctgctgcaa cagcacatgt aactcatcct
    25141 gtaaaacaag gtctaattca atctttgggt gtttttacag atactataat aatatgtagt
    25201 tgtacagcat tcatggtatt attatattca ggttatagta gtagtggagc aactggaatt
    25261 gaattagctc aagaagcttt aacacatcat ataggaccag ttggaaatat atttatagca
    25321 gtttgtatat tcttgtttgc gtttagctct attgttggta attactatta tggtgaatca
    25381 aacatggagt ttatgagtgg aagtaagact aaacttaatg tatttagagt ttttgttgta
    25441 ggtatggttt tatttggttc acttactcaa gtagatgtag tttggaacct tgcagactta
    25501 tttatggcat tgatggcgat aataaactta atagcaatag cacttttagg aaaatatgca
    25561 tttattgctt taaaagatta tacaagtcaa aaaaaatcag gaataaaaga ccctgtattt
    25621 attgcagatg aaatagaagg tctagaaaat gtatcagaat ggcatagaga attacctgag
    25681 gaacatttag gataaaaaaa tagtataaaa ttatgaaatc attttgaaag attagagtat
    25741 ggatatactt tacatgaata tagtattgaa ttaatttata ttactggaac ttttaattcc
    25801 agtaatattt ttttattatg taatttaact ttattaaaag ttttttatca ttgaagatag
    25861 attgtatatt ataaatttta tctttgggtt tcttcttaaa aatattatat aattaaatcc
    25921 tgtaaattat cttcaaagct ttcgaggtaa tcacaaaata atctaaactc ttctatagtt
    25981 ttaatttctt gtaaatttct caaatctatc attatattac tatatttgtg taagataaaa
    26041 ttcatatcat acatttcaca tttgacaaat ccatgttgat aactatattt ataaggttca
    26101 tattttgaaa aattcgactc aaaatatttt attttagcat agcacaattt atgtatatta
    26161 aacaagagtg caagaacaga ttccttaact gcaaatttgt gtgtgaagta ttttatagtg
    26221 tgatatttac tatgtttaaa ctcccaaatt aaatcctcat ttaaagtaag agaatatttt
    26281 tttataagat tacgcttatc tagtgttaaa tcttgtattg aatatgtttt catagtttat
    26341 tctcctcata aatatctaat aagtattaag caatagtatt ttattattaa ttactcttaa
    26401 ttatatttta tggtaaatta aaaaagtaat aaaatagata attagtatac tattagtctg
    26461 ttctataaat aaaaacaata gcttaaatac taatatgctt acttttatgg tattttatgt
    26521 ttggaattat atttgtaatt actgtaagat tttcaaagta gatttgatgg ataatgtata
    26581 attttagaaa gggatgtaaa ttgttttgtg agatttatat acatgattat attaaaaata
    26641 ctaagtatca aaagaagaaa tatagcttct ctctttggta cttagtattt tatatctttt
    26701 acactaattt ttaatattta attaataata ttatttaatt tagagactta aataaatttg
    26761 ccatttctaa tgcattcata gcacaatcat aacctttatt tccagctttt gtaccagctc
    26821 tttcaatagc ttgttcaata ttttctgtag ttacaattcc aaatataact ggtaattcat
    26881 tgtctaaaga tacttttgct atccctttag agacttcact acatacataa tcataatgag
    26941 aagtagctcc tcttataaca catcctaaac agattatagc atcatactta ccacttttag
    27001 ccattttttg agcaacaaga ggaatctcaa aagctccagg tacccaaact atttctatgt
    27061 tttttgtaga aacatcgtgt cttaaaaggc aatcttcagc tcctgataaa agttttgatg
    27121 ttataaattc attaaaacga gaatttatta tacctatttt taaatctttt ccaataagtt
    27181 ttccttcata tatcattttt atttcctcca attttattta tgttatagat ttaaatttat
    27241 aaatatcttt aagtttaatt ataaaaaatt acttagtaga aaaatatccg catataatcg
    27301 cttatataat atctaaaaga tgtcccattt tatctttctt agtttttaga tatagcttat
    27361 taaagtcatt aatttcttca ttaataggga ctctattttc gatttttatt ccatatttct
    27421 ctaattgatt tattttatca gggttattac ttaaaagatt tatacttttt atgtttaaat
    27481 tttttaatat ttgagcagcc atatagaaat ctctcatatc ttcttcaaat ccaagcatta
    27541 aatttgcttc aacagtatca taaccttctt cttgaagttt ataagcttta attttattta
    27601 aaagaccaat acctctacct tcttgcttca tataaattaa aactccactt ccattttcta
    27661 caattttctt catagaagat tctaattgta atccacaatc acattttaaa gagtgaaaca
    27721 catctcctgt taaacattca gaatgaagtc taactagagt attttctcca tttatatttc
    27781 cataagtaag agcaatatgt tcttcatttg aataagtgtc tctatatcct atgatttcaa
    27841 agtttccata ttttgttgga aggaaagcac tagatacttt ctctatagta gtttcattta
    27901 ttttgcggta ttctataagg tcttttatag tgatgatttt taaattatgc ttttctttga
    27961 aaatcatcaa atcatcaact cttgccattg taccatcatc tttcattatt tcacatataa
    28021 gaccaatctc tttaaaacct gcaagtctag caaggtctac tgaagcttct gtatgtccat
    28081 ccctaacaag aactccacca gtttttgcga ttaaaggaaa gatgtgacca ggagttttaa
    28141 aatctttact tgtagaattt tcgtcacaga acaattttac agtttcagct ctttcatatg
    28201 cagatatacc agtcagagta tctgccccat ctatagtaac agtaaaggct gtttggaatg
    28261 tatctgtatt ttctctaacc ataagaggta tattaaggct tttaaatttt ttttcagtag
    28321 caggtagaca aattagacct ctaccatatg tagccataaa atttattgat tcaggagtag
    28381 ccatttcagc tgccatcaat aaatctcctt cattctctct accttcatca tcaactacga
    28441 ttaccatttt cccatttttt atatcttcaa tagcttcttc aatagtatta aacatgtaat
    28501 tcactccttt attattttta aaaaccattt ttaaataaaa aatctttatc tatatttgat
    28561 ttatggttac tactattaga atttaattcc ttgtagttat taaccataaa attattaaca
    28621 tacttcccaa ttacatcact ttctaaatta acgaaatctc caacattctt tgccaagaga
    28681 gtagtgttaa ttttagtatg aggtataata gaaaccttaa atatttcatc atctaaatat
    28741 gatatagtta aacttacacc atcaatagca acagaacctt taagtatcat tgatgataaa
    28801 agttttttat caggtcgtat actcactaaa actgcatttt catctttttc aaatttacag
    28861 atagttcctt taccatcaac atgacctgtt actatatgac caccaaatct cgaagaaaga
    28921 ctcatagctc tttcaagatt taccttgtca tttgcattta ataaacctaa atttgtggaa
    28981 cgaattgtct ccatcataac atcagctgta aattcatttt ttccgagatt tgaaacagtt
    29041 agacaaactc catttacagc tatactatct ccaagatttg tgccatctaa tattttattt
    29101 gatagtatgg ttacttttcc actcttacca ttagcagtaa tttttctaag tattccaact
    29161 tcttctacta tgccagtaaa catcctgacc tcctatatac atgtattaat aaaaatttaa
    29221 tttaaaacat ctgattctat aagaatatct ccatctatca aagttacatt attgattgct
    29281 agctgtgttg aatctgacaa atgatttatt ccttctccag aaacgaatgt aggtgcatct
    29341 ttaccaccta taatcttggg ggatagaaat aatttaacct tatcaactag tctatttcta
    29401 aagagactgt cattaagtgt agcaccacct tcaactagaa cagaatcaat gtttaattct
    29461 cctaatttat acattacaaa ttccaaatct actaagttat tttttgaagg agaaattatt
    29521 gtttcaacat tattttcttt taacatagat aattttttac tttctttgca acatgtgaaa
    29581 actatagttt tactggtttt atctttaacc aaattactat taagtggcaa ctttaggtgt
    29641 gtatctatta ctattcttgt aggatgagat actttttctt gattaagtct acaagttagt
    29701 aagggattat cgttcaaaac tgtatttatg ccaaccatta tactttggta tttatttctg
    29761 tatttatgag ttaggtatct tgatgattca ttagatatcc actttgattc tagtgatttt
    29821 gtagcaattt taccatctag acttactgct gattttacaa tgcaaagagg tcttttgttt
    29881 tttatataat aaaaaaatac ttcattcaaa tctcttgctt cttcttctaa tgttcctaca
    29941 gtaacatcaa tattattatc tcttaatttt tttactccat taccacaaac aagtggattt
    30001 gggtctaatg tagatatgac aactctttta atcttatttt gaataatttt atcaacacaa
    30061 ggaggcgttt ttccataatg agaacatggt tctaaattta cataaagagt agagtctttt
    30121 agactttgtt tagcactgtt tatagcattt acttcagcat gattagagcc aaatttctca
    30181 tgatatcctt tacctattat gtaatcatct ttaacaatta cacatccaac taatggattt
    30241 ggatttacaa agccttctcc atttttagcc aattcaatag cttttttcat ataataaata
    30301 tctttttctt tttgattcac aaaattcaca atatgtacac ctcctgttta attggataat
    30361 ttttaaacaa aaaaccccga gaattaactc agggtttaga ataatctaga ataaatgttt
    30421 aataaatgta caacaaaatt gctctacaaa aacactcatt aaatatcttc ttccatccag
    30481 actttactgt cggctttgga atttaaccaa atcaaccaag ttttacattg gctcgcgggc
    30541 tataccgccg attgggaatt tcaccctacc ccgaagatta agtattaaat ttatatttag
    30601 aatgtatcat aaattatttt actttgcaaa ctattttttt taaaaatata tgttaatata
    30661 taatatagaa tgtctataaa ctttgaaata ccacgattgt gaatataaaa ataaaaattt
    30721 gaacataatc aggaaagaag tctaattaat ttaaattagg agagtaatat atgaataaaa
    30781 aacttttaga aatactatca aaatattatg gatatacaag ttttagaaaa ggtcaggaat
    30841 ctataataaa ttctatctta aacgaaaaag atgtattagc tattatgcca acaggagggg
    30901 gaaaatcaat atgttatcag attccagctt tgattttaga tggaatgaca atagtaattt
    30961 ctccacttat atctcttatg aaagaccaag tagatgcatt aaaagctatg ggaattagtg
    31021 ctgcttttat aaatagttca ttaagtagca aagaatttaa tgaaatatta aacaatatta
    31081 gaaaaaataa ttataaaata ctctatattg ctccagagag attagatgca caggagtttc
    31141 ttgagctaat aaataataac aatgtaagtc aagttgcaat agacgaagca cattgtgtat
    31201 ctcaatgggg acatgatttt aggttgagtt atagaaggat ttctgatttt ataaaaagtt
    31261 tgcctaaaag acctatagtt acagcattta ctgcaacagc ttcagaagag gtaagaattg
    31321 atataataaa tttactgtgt ttagaaaacc cagattatta tataactgga tttgatagag
    31381 agaatttatc gataaatata gtaaaatcat ctagtaaaaa taagtatatt ttagattata
    31441 ttcaaaacca taaaaatgag tctggaatta tatatgttgc aactaggaag gaagttgaaa
    31501 atatatataa tggtttatct aagagaaata tttctgtgtc aaaatatcat gcaggtctat
    31561 ctaaaaacga aagaagtaaa aatcaagaag actttataaa tgataatgtg gatataatgg
    31621 tagcaacaaa tgcatttgga atgggtattg ataaacctaa tataagatgg gttatacatt
    31681 acaatatgcc tcaaagtata gaaaattact atcaagaaat aggtagagct ggtagggatg
    31741 gagaaaaaag tgagtgtgta cttttatttt ctccaggaga tgtacatata caaaaatatt
    31801 taattgatat tggagttgaa aatcctgaaa gaaaattatt tcagcataag aagcttcaat
    31861 atatgattga cttagtttac agtaattcat gctatagaaa gacaatattg aattattttg
    31921 gagaaaatta tatggacaat tgcaataatt gtagtaattg tttagtagag ggtgaaatag
    31981 tagataaaac tatagatgca caaaaagtca tttcatgtgt agctagaatg aaaaggagtt
    32041 atggtgttac tactattgta gatgtactta gaggttctaa aaataaaaag attttacagc
    32101 ttggactaaa tactttgtct acatataata ttatgagaga ttattctagt gaagatttaa
    32161 agaattttat aaatacatta gtatctcatg gttttttaga tttagttgag actctaggta
    32221 atggaaatag aggtagtttt ccaactataa gattaaatga aatgtctatg aaagtgttaa
    32281 aaggtgaagt gaaagtagaa tttaaagaga ttgtgatgac aaaatcattg gaagtagaag
    32341 atgagttata taatgtttta agagaactta gacattcaat tgcaagtgaa gaaaggatag
    32401 ctccatatat ggtatttgga gatggcacgc ttagagccat gtctagtagt tatccaatta
    32461 ataaagaaga aatgctagat atctctggag taggagaaat taaatatcaa aaatatggta
    32521 gagattttga aacagtaatt aaagaatatg tcgaaaaaaa taatataaat aaaaaaataa
    32581 atgaaaaaaa tgtcgattta aaaaacgtta atagtgattt cctagaggtt aatacagata
    32641 aagttctata tgaaaaactg ttagtcatta gagaggaata tgcaacgaag gaaaaattac
    32701 ctgaatatat gattttagct aataagactt tgaaagaaat aagtggaagg tatccacttg
    32761 atgaagaaca attaaaagat atttctggaa taggtggggt aaagtttgaa aagtatggag
    32821 ctagtatttt agaagaggtt aataaatatg taaaagaaaa tgatattaat gttatttggg
    32881 agaaaaaggg gaaaaggaag ttaatattag atggagaaag tagaaaaaat aatgaaatag
    32941 ccttagattt actgaatcaa ggaaaagaca tacaaagtat aagtcaagaa atagaagttt
    33001 cactgtcaac cattattgga tatgtgcatg actatgtaaa ggatggacat agaatatcat
    33061 ttgaattagg gttagaaaat ttttataatg aagataaaaa gaagatgatt ttagaagttt
    33121 gcgaaaaagt aggttatgat aatttaaata acataaaaag aaaacttcca gattcaataa
    33181 agtatgaaaa tataagagct gtgatacttg actcttatct tgaaaactta aaaaataata
    33241 ttatagcaga gtaattttta acttaataaa aaataaaatt tgtattatta tgttgaacta
    33301 atatttttgc tgtgttatac tgaatttgta aaaataatga aaaattagag ctaggggcgc
    33361 tagaattggc tagctgagag ataaagccgt aacttacaaa ccctaataac ctgatcaaga
    33421 taatgcttgc gaagggaagc tttttaatat aattttatta tataaatagg caaattattt
    33481 aatgttaggg taaatttgtc taagtgtata tacgattata agagtgcttt ccaaacaagg
    33541 aaaagcactt tttttatttt caaaaactat aactttaatc ttggaggatt gtaatatgaa
    33601 ctatacaaca caaatggatg ctgctagaaa aggcataata actaaagaaa tggaaatcgt
    33661 ttctcaaaaa gaacaggtag atgtaaatga attaagagaa ttaatagcaa atggacaagt
    33721 tgttatacca gccaataaaa atcataaatc tttaagtgca gaaggtgtag gtaaaaattt
    33781 aagaacaaaa ataaatgtaa atctaggaat ttcaagagac tgtaaggata tagaaaaaga
    33841 acttgaaaag gttagagtag caatagacat gaaagctgaa gctataatgg atttaagtaa
    33901 ttatggtaaa actagagaat ttagagaaaa agttgttgaa atgtcacctg caatgatagg
    33961 ttcagtacct atgtatgatg cagtaggata tttggaaaaa gaattaaaag atataacaga
    34021 agaagagttt ttaaatgtaa taagacaaca tgctattgat ggagtagact ttattactat
    34081 acatgcaggt cttacaagaa gtgtttgcca aaaagtaaaa aatcatgagc gattaactca
    34141 tatagtatct cgtggaggtt ctttattgtt tgcatggatg gaattaaata ataaggaaaa
    34201 tcctatttat actaattttg ataaaatatt ggatatatgt gaggaatatg atgttacatt
    34261 gagtttagga gatgcttgta gaccaggttg tataaaagat tctactgacg gtgttcaaat
    34321 tcaagaactt gtagtattag gtgaacttac taaaagagcc tgggaaagaa atgtacaagt
    34381 aatgatagaa ggtcctggac acatggctat tgatgaaata gaagcaaatg tagtattaga
    34441 aaagagatta tgccatggag caccttttta tgttcttgga ccattagtta cagatatagc
    34501 accaggttat gaccatataa caagtgcaat aggaggagct ttagcatgtg ctaaaggagt
    34561 ggatttttta tgttatgtaa ctccagcaga gcatttaaga ctgcctaatt tagatgatat
    34621 gaaagaaggt ataatagctg caaagatagc tgctcatgca ggagatatag ctaaaaatgt
    34681 taaaggtgct cgtgaatggg ataataagat gagtaaagct agagctgatt tagactggtg
    34741 cgagatgttt aggcttgcaa tagaccctga aaaggctaag agatacagag atgaatcaac
    34801 tcctactcat gaagatagtt gtactatgtg tggaaaaatg tgctcaatga gaacggttaa
    34861 gaaaatatta aacaatgagg aacttaattt aatataattg ttggatagta tgactaaagt
    34921 aaaaagaagt tgaaaagagg aggtgattta gtgaaagtta atggtaagga aattgaattt
    34981 gaagaaaatt tgactgttat agatttatta aataaatata atttaaagag tgatagagtt
    35041 gtagttgaag tgaatttaga gataattgaa gaatctaact acaatacata tgtattaaaa
    35101 gacgaggata ttgtagagct tattagcttt attggaggtg gttaaaataa aaatatttgt
    35161 aaatgaatca ttaacagatg ttgaggaaaa tacaactgct tataaagtta gagatagcta
    35221 taacaataaa tgtgatgtat tagtgttaaa tggatatcca attaaaacag atatgcccct
    35281 ttgtgaaaat gataaattaa cacttataca aaaaggcatt aagccatcac ttgatgagtt
    35341 ggaaagtttg ctgattgcta gacatactcc aaatatacat aataagttaa aaaaagggaa
    35401 ggttgctata ttgggattgg gaggacttgg ttccaatata gctatctctt tagctagaat
    35461 tggagtggga gaacttttac ttatagatta tgatgttgta gaaccatcta acttgaatag
    35521 acaacagtat tttatagatg atataggaaa actaaaaact gatgccatga tagaaaacat
    35581 aaaaaaaata aatcctttta taaaattaaa taaacgagat gtttttttaa acaaaaataa
    35641 tatggacact attaaagact cagatttaat aattgaggca tttgatgatg cttcatgtaa
    35701 ggcacaggta tgtaattatg tattaataaa tttaaaagat aaatatctaa tagcatcatc
    35761 tggtatggca ggttattatg attcaaatat aataactact aagaagataa aagacaggtt
    35821 ttatatatgt ggggactttg tgaatgaagc taaatttggt gaaggactta tggctccaag
    35881 ggttgctatc tgtgcaaatc atatggcaaa tttggcaaca caaatactta tagatatgta
    35941 aatattaaaa ttagacacta aaaagattga atattaaaaa aatttaatat ggagggaaat
    36001 aatatggata aattggtact tggtggacat gaatttaata gcagattatt ggttggaaca
    36061 ggtaaatatg gttcaaataa tatattgcct gaggtaataa aagaaagtgg aagtgaaata
    36121 ataacaatgg cacttagaag agtggattta gacaataagc aagaaaacat attaacatat
    36181 attccaaaag aaatgacaat acttccaaat acatcaggag ctactaatgc agaagaagct
    36241 gtaagaatag ctagaatatc tagaaaaatg ggatgtggag attttataaa aatagaagta
    36301 atatcagata ctagatatct acttcctgat aatgaagaaa ctataaaggc tacaaagata
    36361 cttgctgatg aggggtttat agttcttccg tatatgacac cagaccttta tgctggaaga
    36421 aggcttatag aagctaatgc agcagcagtt atgccacttg gagctccaat tggttcaaat
    36481 agaggtcttc aaatgaaaga gatgataaga ataatgatag atgagttgga tataccaata
    36541 atagtagatg caggtattgg aaaaccatct caagctatgg aggctatgga aatgggagct
    36601 gatgcagtac ttgtcaatac tgctatagct tcagcaggag accctataca aatggctaga
    36661 gcatttaaat tagctgtaga aggtggaaga gaagcatata tcgcaaaaac aggaagtgtg
    36721 tcagaatttg caaatgcttc ttctccttta acaggttttt taggcaattt atagaaagtg
    36781 gtgattggtg atgagttttt atgatgtaat agaaaaatat aggaattttg attttgatgg
    36841 atatttaaat aatgttactg ataatgatgt tttaagaagt ttatcaaaag acaagcttga
    36901 ggattttgat atattaaatt tgctttctaa aactgcagta aaacatttag aagccatggc
    36961 acaaaaagca cataaattaa gtgttcaata ctttggtaaa acagtatgtt tatatacgcc
    37021 aatgtatata gcaaattatt gtgttaatca atgtgtttat tgtagctata atataaaaag
    37081 tggaataaaa agaaaaaaat taaccatgga tgaaattaga gaagagggag aagcaatttc
    37141 aaaagaaggt tttaaacatc tacttgtctt gactggagaa agtagttttc actcaagtgt
    37201 agaatatata ggtgaggcta tagaaatatt aagagaaaaa tttccctcta tagggataga
    37261 agtttatcca atggaagtag aagaatataa gtacattgta gataaaggtg ttgaaggact
    37321 aacagtatat caagaaactt atgacgagga aatatataag agagtacata taaaagggcc
    37381 aaaatcaaat tataaattta gactagatgc tcctgaaaga ggggcaaaag caggtatgag
    37441 gactttatca ataggtgcac ttttaggatt aaatgatttt agaaaagaaa ctttttttac
    37501 aatattgcat gggaaatact taaaaacaaa atatccttat attgagcttt catattcaac
    37561 accaagaatg agacctttta aaggttgttt tgaggaattg gtagatataa gtgatactga
    37621 tttagttcaa gctatggtat gtatgagatt atttgaccct catgcagcta taaatatatc
    37681 aactagagaa aatttagaaa tgagaagtca tataatacct ttgggagtaa ctaaattgag
    37741 tgcaggtgta tctactgatg taggaggtca ttctcaagat gaacatgata cagctcaatt
    37801 taagataaat gatgaaagta ctgttaaaga tgtggagaaa atgctaaact caattggtta
    37861 tcagcatgtg tttaaagatt gggaaagatt ttaaatgtat ttgataacaa acagaaagtt
    37921 atgtagtgaa gaacgatatt tagaagttat taaagagtct atattgagtg gtgtagaaaa
    37981 tatcataata agagaaaagg atttagaata tcaagagcta aaaaatttat atatgaaaat
    38041 aaaaactaaa atcaattgta tagattttca agagcaaata tcagatgaaa gtttgaaaac
    38101 taatataaat caaaaagggt gtggaaataa attcaaggtt aattttataa taaatagtaa
    38161 cattgaattt tttgaaaaaa tggattgtca aggtatccat cttcctttta aattattctt
    38221 gaatttaatt gaaaataagt ataattttaa tgaaaataaa atactaggat tatctttaca
    38281 caaagtagat gaagtagaat atttagaaaa attaataaga aagcaaaata taaaaataga
    38341 ttacataaca ttatcacata tatatgaaac taaatgtaaa gaaggattaa atccaaaagg
    38401 aattgagctt ttaaaagaag ctaaaaagat tactgatatt aaaataattg cacttggggg
    38461 aattttacca tctaatgtca aagaaacatt aaaatactgt gatgattttg ctgtaatgtc
    38521 gactataatg aagtctaaag atattaaaaa aaccatatca aattataatg aaaagttaaa
    38581 ttagtaaata tagtatgttg aatttttaac ttaaataaaa ataagaaagc tatcttttaa
    38641 attttaaaag gtagcttttt attttgtatc tttgctaata aaaaattgta aaaagggaaa
    38701 actttagtca gagagattaa caatatccta gaaagattta aaatttagta aagtatggag
    38761 gacattataa tgactgacag taaaaagaaa cgatttgtta taccacacac ttttacaata
    38821 atatttttac taatagtctt aatggcaata ttgacttgga tagtaccaag tggtgaattt
    38881 agtagagaag atgtagaagg cagaatggta gttgtaccag ggacttatca aagtgtagaa
    38941 agcaatccac aaggatttgc agatgttttt aaagcaccaa tagaaggatt tatcgattca
    39001 gctgaagttg taggttttgt tttaatagtt ggaggtgctt ttggtattgt aaataggact
    39061 ggagctatag aagcaggaat agcttcggtt atctctaagt ttaagggaaa agaacttctt
    39121 ataattccaa tatcaatgat tttatttgga cttggaggta caacatttgg gatggcagaa
    39181 gagacattac cattttatat gatatttgtt ccacttatga catccttggg atatgattct
    39241 ctaacagcga tagcaattgt atttatagga gcagcagcag gagccgcagc ttcaacaata
    39301 aatccatttt cagttggtat tgcacaggca ctagctcaac ttgctcctgg ttcaggagta
    39361 acttatagag tagttatttt tatagcatat atactaataa gtatagcatt tgtcatgtac
    39421 tatgctaaga aggtaaagga aaatcctgaa agttcaatag tatatgaaat agataaaaat
    39481 aataaatcaa tacttaatca aacttcaaca gaaataaaag aatttacttt taaagaagta
    39541 tctgttcttg ctatatttgg aatagggatg gcaataatga tttggggtgt tttaagtcaa
    39601 gggtggtaca ttccagaaat atcaatgtgt tttgctgcga taggtgtgct ttctgggctg
    39661 gctggtagat tatctcaaat tgaaatttca gaaagtttta tagatggagc aaaagattta
    39721 gcatcagcag ctcttgccat agctttagct cgtggaatcg taataattgc tcaaaatgga
    39781 tttataatag atactatatt aaattccgca gcagcttttt taggtgggct tccaaaggtt
    39841 atatttgtat atttatcatt tttcttggaa gctgcattgg catttttaat tccatcatct
    39901 tcaggacttg cttcacttac agtacccgta cttgctcctc ttggtgattt ggttaatata
    39961 tcagcacaag tgatagtaac tgcttatcaa tttggtgtag gtcttacaaa ctttataact
    40021 ccaacttcag gagttttgat gggagcactt gcagtagccc atataccatt ttcaaaatgg
    40081 gtaagattca taatgcctat tctgttgatt ttaacagctg tatctctagt ctttttaaca
    40141 ataggcattt atatagggtt ttaattaagt atatttttat ttaagatatt tagtaatgat
    40201 ataaaatgat aatatgtttt caataaatta ccactaattt aattagtggt aatttgtttt
    40261 ttgtatttag aaataaatgt atttacttgt gttttgaatt attatctact tagacatagt
    40321 tttaattgtt atatttttat ttg
//
LOCUS       DAMKOJ010000032        40220 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000032 DAMKOJ010000000
VERSION     DAMKOJ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40220
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.034"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(1102..2133)
                     /locus_tag="PC592_001793"
     CDS             complement(1102..2133)
                     /locus_tag="PC592_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055768.1"
                     /translation="MKIEMGESLLYSWLRHVKECQIVQTNWKVSSKWDLKNADKILEI
                     MEKTKQYFEQKYGYPIYKNNSLEQLIMQAEVDVLGISIDNGRNHIYAIDVAFHEAGLN
                     YGSKNETVTRVIKKCIRTAMCIYGYMDLDEAEIIFASPKINPAIITELEPKMAEVNDL
                     FKSLGLRFKTRLIANEEFNGKILEPILIASDGISDTSELFLRSYQMYSMFSYSRDVVK
                     QQRIKKSNSLKDAVELNLSDETLKELKIGKLVQVTMKHLFEEEKISPEEIDKMTQSSY
                     SKQVFNENKPVLKEVPKDGNINELKKDEKNYNRYYAYTISIYGKQYLLVSQWIEDLHR
                     SYYESWVIK"
     gene            complement(2284..2934)
                     /locus_tag="PC592_001794"
     CDS             complement(2284..2934)
                     /locus_tag="PC592_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055769.1"
                     /translation="MEVIRNMTNVSSLEKEDEIVEILSSKENIRVAIEIERGLKLCKT
                     QMIKKVLEEIEKRMDKKFEDKYKLPYYSYKENNYALVNNYYNKKSSTYPAINYFIKSL
                     DKEDVDLLLRIEIDHHIFVGFCTLYKEKPSGKILSDDEIKELINDDGSRTNGWWICWE
                     YIYNNTMECPNFKNFNDAYFDLFDDNKFDEFMDLCEKRILSILGKLKDKQCINTFI"
     gene            3127..3585
                     /locus_tag="PC592_001795"
     CDS             3127..3585
                     /locus_tag="PC592_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HDF4055770.1"
                     /translation="MSVDTLRNQFIKIVIEIYEDLTEFIFSKDIQTDKNLDFILKEPK
                     YIPNGFKEVEKENTLQGIFIRYENKNGSEIRYRSNQIDSNTVILDTENAKVTDIMVND
                     YEAKYIVKDNSITIFWNDEENVYTIYFDYDNKNDLNKYKDNLIDIAENIK"
     gene            3660..4082
                     /locus_tag="PC592_001796"
     CDS             3660..4082
                     /locus_tag="PC592_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055771.1"
                     /translation="MYLKKVIVAGLCTLTCLLPLNVQAFEDTSLNTNDYNQTNDNDLF
                     MIYIKGAGSNLSIRSGKAHISCYVDGKIGSLTSITARLQQKKSGKWVTISTWSSSGKT
                     SSTLSREYRVSKGYSYRILTTIKAGNESRNITSNVTNY"
     gene            4112..4798
                     /locus_tag="PC592_001797"
     CDS             4112..4798
                     /locus_tag="PC592_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055772.1"
                     /translation="MKYFKKVIALGLSIALLIPVISINALEKKDTNVNNQIINVIESN
                     VSYTKEGIEVSSDLKNDLKEINLEDIKEQMIEQGIDSKFINNFNSDVIYSLVKENIDD
                     INEGVKNKTLKITPEEDIINNTDNSFYVQGGSTYTQKFSWGVRQNKSTAAANRWVYDL
                     NKSSQGFVATGAVSVLLGSMGAPIGFVSGLSAAYMGGLANKVSYVNSRNNRGITVDIN
                     WWLTYAVKNQ"
     gene            4946..5758
                     /locus_tag="PC592_001798"
     CDS             4946..5758
                     /locus_tag="PC592_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8/S53 family peptidase"
                     /protein_id="HDF4055773.1"
                     /translation="MNYSDMHEISSGKSQKIALIDSGISKFQKVYKNINLTNSNNDYD
                     TNGHGTMMYSIIKGYNKNNQTIEGISPDSRIILIKVMNDDESINPNVIEDAIDYALNE
                     KVDIISLSLGSTKTDINIKQKIDKANLKNITVVSSAGDYKQGFLLFPASLNNVISVGS
                     IDDRRDISTLTNAPQKTLINAPGEKIKVIDNNNNVFYGKGTSEATAIITGYIALMRDT
                     NISSTQILTNEKIMNLLSQINKNEKTYLGALKEIRKKVSVSTGAFFSFDLSY"
     gene            complement(6703..7059)
                     /locus_tag="PC592_001799"
     CDS             complement(6703..7059)
                     /locus_tag="PC592_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HDF4055774.1"
                     /translation="MNIIYEKEFTFDNKVREFISLGNNYKFEFSTSKSPKTLIKYFMD
                     YNKISSNKLESFKEKYSFKKNELLSLQEILKNKFTEDDKLESLKLSKANLENELKLGN
                     SIIKKSNSNHNMVEKK"
     gene            complement(7175..7405)
                     /locus_tag="PC592_001800"
     CDS             complement(7175..7405)
                     /locus_tag="PC592_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4055775.1"
                     /translation="MSYAETKACACSDDSILKLCEINREIQIIEINKKAFLNQNLLTL
                     NDIKSTENSIDALKISISKLEEDIKTYFSNFF"
     gene            complement(7578..9791)
                     /locus_tag="PC592_001801"
     CDS             complement(7578..9791)
                     /locus_tag="PC592_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF4055776.1"
                     /translation="MNQSYHNIKNELLSKQLAYIDRLTGYLVDRDNYLSGYVKEKLKI
                     AKEASIKDNTFLVNVKALEANQPKYETDVFFSIDSTWISSSIKSDFIEKTLELKENSI
                     QLLYSTQLGYSVKCSDIIPISKNEFTWGTKRRKSLYIVEAELNMKTITVTDKEYQNGK
                     EVSVKNLEETQLAMNILNKWLIAFHNYVTSNSYIHKELLDRYNEMFIDYKEKEYKNIL
                     NDVRINPNIKLREHQLKAASRIITSDRNTLLCHSVGSGKTYTMITAAQELNRISKIDS
                     KKGNKNLFVIPNSLCESGQFAKEYFNLYPQANILATTSKDFSKSNRRKIIAKIVTCNW
                     DSIIIPHSVLGLIPLEADTELKLLDLYLKELNDTLKYYKKECPDLSTKRLETMKENYL
                     NRIKELNDMHKDDALLSFEKLGITNLFIDEAHNFKNLYFNTTMQVPGISTLKTKKTQD
                     LYNKLRYFKSIHGNKGVTFATATPISNSICEMYTLLTYLNKDTLKYYKVDTFNAWASK
                     FGSIISSMEVDPTGQGFRFQQRFAKFCNVPELVNIFRQIADVVNICDINDLDIPQIKG
                     GKPIIEIIKPTNQMKEYIDSLVKRAEKIHEGPYDPIIDNMLNVTTDGRLMAVSPALVG
                     IDGILPKIIKVGENIASLYHEDKISTHLVFCDLGTPNGNSHNVYNDIKNELLKNNVLE
                     KDIAYIHDANTPEKRKKLIDDFNNGIIRILIGSTSKITSSCRCSLETFINFTKRR"
     gene            complement(10287..10853)
                     /locus_tag="PC592_001802"
     CDS             complement(10287..10853)
                     /locus_tag="PC592_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055777.1"
                     /translation="MNNLFYDKLNFDDKLIIKNNGVIRNNDLYFLKYKNDTAGILIYN
                     IINDKFSFKQNKNYKGMNPFPITNIFKNLDSDKWDEFIRIWIEERVIQECRPEVPFIL
                     KEFKLGYYDVWDICRSNLAMSVEDFFWITKDNTLRYEDFNIRYCTLNNITPIYKPPFP
                     IVIYPNYFEREKIKSGETWKYELKNTNS"
     gene            complement(11255..12307)
                     /locus_tag="PC592_001803"
     CDS             complement(11255..12307)
                     /locus_tag="PC592_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055778.1"
                     /translation="MNVINVFNINLKRNINKRIVFLVTLLFPIIIVILGVLANYISKP
                     FFNIGILDEYKNERVLKESEKRTYENTIMALENTQGINTKIADFKTIKTDIITGKYSA
                     VIYFNKNGFKLYSIKNKNTNDTLKYLIETYKKDPVPVDISKLQENTLGVLQRIIAFIV
                     LFLMITSTVTASMIIKDKNSGTFTRVLYSPQNVRGYVLGNMLYNFTITYFQYIVSISI
                     IKLFNIDIGMDYIDLILMGIWVVALATSFGTFVSSLFNREMHANLFSTCISLVLSLIG
                     GSFISVEKMPEMLQKISIISPVRWFISFVTYIEERDGSFFNMNYICILTSIIIVLALL
                     AMKFTQRSKYSSNSNY"
     gene            complement(12307..13047)
                     /locus_tag="PC592_001804"
     CDS             complement(12307..13047)
                     /locus_tag="PC592_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055779.1"
                     /translation="MRCFLPLFKLGIKRRSKDFFILFYNIVFPVIIIMLLGYLTSKSY
                     GEEFTSYNYYTIVTIPFCVLMGIISVSYAGQDEKISNTSYRYMISPISIVDLVISKLF
                     SCTAVLSICNLVTLVVLKCIFRMSFGGKFLAVLFFLMCESIVVVSMGLFLGLVCKNLD
                     MLRNIINIPIVIFGFLGGVFFPVSSLNPVISLIINISPLTWINRGIVACIYDNNLQLL
                     FNISCIFVVVSIFMTILTIKFFKKGVFI"
     gene            complement(13052..13810)
                     /locus_tag="PC592_001805"
     CDS             complement(13052..13810)
                     /locus_tag="PC592_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055780.1"
                     /translation="MSNILLEIKNLSKKYNNKEVVSIESFKLLEGDILGFIGANGAGK
                     STSINMLTTIVSPDSGSIYYKGKDIKNQQNIFKSSLGVVPQELAIYEDLSAYDNVKFF
                     CSLYGFKGNELKERTKDALEFVGLWESHKEFPSKFSGGMKRRLNIACAIAHSPKILIM
                     DEPTVGIDPQSRNKILEAIKCINTNGTTVIYTSHYMEEIETLCNRIALIDKGIIIEDL
                     DKSLYKNKYLEFGCKTLEDIFLYLTGTDLRDLEE"
     gene            complement(13912..14634)
                     /locus_tag="PC592_001806"
     CDS             complement(13912..14634)
                     /locus_tag="PC592_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF4055781.1"
                     /translation="MIRTLILYYLNIKPTHGYEIQKFLQVSGADRWTKIQSGSIYYAL
                     AKLEKDGGVRVLKEEKTGARIRKIYEITQSGKLELREEIQKELQMPIVPTGSNKFLLH
                     NILDVLPKDTLQKNLEKHIKYLIEQKKYWENWKEIKKIDKKSLATEKIAFDMTIDNLN
                     YQILWHEEILNDIDKYISVGCETQNIIKSIDFSNIEEDFLFTSDTTNELLEVQRLRDE
                     IINNPDKAIENIDKIILKLQNK"
     gene            complement(14735..15340)
                     /locus_tag="PC592_001807"
     CDS             complement(14735..15340)
                     /locus_tag="PC592_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4055782.1"
                     /translation="MKIKENVLRLDSTRGSNCFIVFDKEITLIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHMSNIKLLKEKTGAKVWAHTEDIPFIIGEKDRPGFKK
                     FIGKTISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVSYPNPWNWDSKKMMKSIRELDNLEYEWICMSHGTPCIK"
     gene            15520..16158
                     /locus_tag="PC592_001808"
     CDS             15520..16158
                     /locus_tag="PC592_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4055783.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFSLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSKKSDTEMLFKEKFFSFNKFMFDEIQEMFEIGKNDGSIRYDI
                     EISTLMYSSIFTLTGFFNLLSVTRKSYLNNFNIDEEKFIETTLAILIDSIKA"
     gene            16274..16936
                     /locus_tag="PC592_001809"
     CDS             16274..16936
                     /locus_tag="PC592_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055784.1"
                     /translation="MAKILLLEDDDTITFGIKTSLENKNHIVCCYNTIAEAKKNFDKT
                     TDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRAHSNTNNTITCGNISLNKVEVKAYLDSVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            16936..18117
                     /locus_tag="PC592_001810"
     CDS             16936..18117
                     /locus_tag="PC592_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055785.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKVL
                     DASYEYNPKSTESILKSLKNSSDEDFKTGNEILSKHGYSKGTFWSKNFFYFLVVSFGI
                     ISTMAIVVYIIKYRTNKQKLSRINMLTRYLEEVNLGKESVLLRYEDEFSYLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TKQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     KGSPSIEFEIDINWTLEALLNILKNCSEHIEAGGHIIAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(18294..20954)
                     /locus_tag="PC592_001811"
     CDS             complement(18294..20954)
                     /locus_tag="PC592_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055786.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDDTYGKDLSLIENFSSVDDVMVKGQWYVGKINNDKRDYI
                     VYRNATSEYWNHMPEKDSIIEGRRPSNTNEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPVAPKSKGESFKKISKTTLTIVGKVDVATSSVVPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SNISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNKLIVYINSVNYHTDAPEVVFTYGIPAFLPAVLL
                     TIVTVWISTLIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTGFLHIIANQEGAEAVYGSDNYKDQRDIEVYLENSEPVE
                     SDFIEKLDNTEGVKNSLYYQKMSATTWLTEKDASKELSKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDESFAEYCRQISVDPKLFYDTKNPTSIVYNKEEDVNRSTRRNKVY
                     IDYLNLSIGDNIKLNEKIYDEDKGDYTYNMKVGAITSTLPKIIDTSSRYTLMQIVPIS
                     MVQEISKNYAEVGRSRSNRLIGLFKVDNREDIPRVRGKLESICNKDYGSGDYSIEDVV
                     ENEKQNGSGRKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPD
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYTFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYNQLKNENIVESIKSETI"
     gene            complement(20951..21634)
                     /locus_tag="PC592_001812"
     CDS             complement(20951..21634)
                     /locus_tag="PC592_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055787.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHMLGGVDRPTSGKIYVEDTEISSLNEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     TILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(21983..22915)
                     /gene="blaCDD"
                     /locus_tag="PC592_001813"
     CDS             complement(21983..22915)
                     /gene="blaCDD"
                     /locus_tag="PC592_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF4055788.1"
                     /translation="MKRKKNFIWTTILLVGIVMVMYYAGKKHNDINQKTDKNYIKSDL
                     NKSEINNDNNKKERVNIVNYSDCFEGISGGAIFYNSRNQEYNIYNKDLIETRASPCST
                     FKIISTLIGLEKGVITSKKSVIGYDGTNYPNKNWNKNLSLEEAFKESCVWYYKKLINK
                     VDAKSVQSILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMVKIF
                     EGDTNFKKEHINILKDIMKIDVSDKNINVYGKTGTGFNGKNKRVDAWFVGMLESKDDT
                     YYFAIKSDDSNKEIAGPKVKEIAINIIKKYYSVM"
     gene            complement(23455..25569)
                     /locus_tag="PC592_001814"
     CDS             complement(23455..25569)
                     /locus_tag="PC592_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HDF4055789.1"
                     /translation="MFEDKQVINCDTIASNSKHNMYEHDTELLTFFPDEIAHLIDINN
                     KLDDAFKKAENLVDKLDKDYMDTKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKIDKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKAHTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     AERVRFKSTFDFVKLIDYYIKQMPNKIFIPKDYNFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKLKSILKSLNGMLTIKNTLTLYKDFFKQMNLSN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGGFGQLVNPNHTHTLDDMRQLYNEGELVTLNKSYRSTFEIINFAKKVQDVSS
                     LEPIERHGEEPALVKCTNKQDEVSKIKIEIEEFKKSDNATLGIILKTDSDAEVIYNAL
                     KQEYSVNLISSESSSFTKGVSITSIKMSKGLEFDEVIIPSVNSKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(25816..26676)
                     /locus_tag="PC592_001815"
     CDS             complement(25816..26676)
                     /locus_tag="PC592_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055790.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLANMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSEIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     SVEETDTRPN"
     gene            complement(26867..27481)
                     /locus_tag="PC592_001816"
     CDS             complement(26867..27481)
                     /locus_tag="PC592_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF4055791.1"
                     /translation="MNEKWLEWAIELQSIAQAGITYGKDIYDRERYERIREISAEIIA
                     YKTDISTEKVRNLFCNESGYQTPKLDTRAAIFENGKILLVKENTGKWSLPGGWVEVNL
                     SVKENTIKEVKEEAGLDITADRIIAIQDRAKHNLPIYAYGVCKIFVLCTVIGGEFKEN
                     IETTEFSYFSENELPELATEKNTEEQIKMCFKACRTDTWTVIFD"
     gene            complement(27549..27911)
                     /locus_tag="PC592_001817"
     CDS             complement(27549..27911)
                     /locus_tag="PC592_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF4055792.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDEALKPFVETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQE"
     gene            complement(28131..28595)
                     /locus_tag="PC592_001818"
     CDS             complement(28131..28595)
                     /locus_tag="PC592_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF4055793.1"
                     /translation="MTRISNITIAEQSEYCILAIRKTIDFVVEFSEFSKQSLEKISKY
                     LEERGILSSGAPIVCFHNMDLAELDVEVGFPVATYIDGKNEILQRIIPSQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(28905..30326)
                     /gene="nhaC"
                     /locus_tag="PC592_001819"
     CDS             complement(28905..30326)
                     /gene="nhaC"
                     /locus_tag="PC592_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF4055794.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNVFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPVGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLKLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDI"
     gene            complement(30356..31420)
                     /locus_tag="PC592_001820"
     CDS             complement(30356..31420)
                     /locus_tag="PC592_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HDF4055795.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEVV
                     KAICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFYNVREIIKLKNIKIIGIATNLT
                     CYGAIIPSRENIGRLASIAQKMEGKFGINLEIVSGGNSSSIHLMTNDNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGFDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDSVEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(31405..32814)
                     /locus_tag="PC592_001821"
     CDS             complement(31405..32814)
                     /locus_tag="PC592_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HDF4055796.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHNIDTNNPVFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDNIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQVTSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNIENQEEVRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKIKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(32814..35018)
                     /locus_tag="PC592_001822"
     CDS             complement(32814..35018)
                     /locus_tag="PC592_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF4055797.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYR
                     DCTKPLKDSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLRIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELREKARELKERAVLYMEEIFEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDKNAIDNPSILIDGCTFENPDKIIYIDELDDFDNVENRLKESDEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQETEVISREVMHESEGTRIEVKGRV
                     PFDIDLKNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMNNK"
     gene            complement(35012..35386)
                     /locus_tag="PC592_001823"
     CDS             complement(35012..35386)
                     /locus_tag="PC592_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HDF4055798.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVNGEYWDEVTCLFREGVESC"
     gene            complement(35464..36894)
                     /locus_tag="PC592_001824"
     CDS             complement(35464..36894)
                     /locus_tag="PC592_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HDF4055799.1"
                     /translation="MNNSASMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEVIQSQYAVGNTPIIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKKMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVIDVLNSL"
     gene            complement(36887..37195)
                     /locus_tag="PC592_001825"
     CDS             complement(36887..37195)
                     /locus_tag="PC592_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HDF4055800.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVSNE
                     "
     gene            complement(37293..38360)
                     /locus_tag="PC592_001826"
     CDS             complement(37293..38360)
                     /locus_tag="PC592_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HDF4055801.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKILFLLNRKINVIS
                     TAEQMAYPQADDVDLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGATREEFIKGVEDKTIAGHVGFVESINMIADGLGWRL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(38620..39993)
                     /locus_tag="PC592_001827"
     CDS             complement(38620..39993)
                     /locus_tag="PC592_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4055802.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREIIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     RVIGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESKNYSLNDLEDKTLSKIISEIEEKYIYESLEKTSYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
BASE COUNT        13398 a         6505 c         4629 g        15688 t
ORIGIN      
        1 tcttttatat tactaaaagt tacatattta tatgtatttt atttttatca aatctatcta
       61 taagtttatc ttttcttcgc tgtatcctgt agatacaaag gcataataca ctagtttcaa
      121 atatttcccc caattttcta aatattttca ctttttcgtt ttattactat gaagtctatg
      181 atataatttt aaaaagagat actttccaat aaaaaagtta ttttaaacct attattaaaa
      241 ttttgaaagt tgttgatgat tatgaataaa aaaaatatat tcaacgatat gtttcttatt
      301 gtttatccaa ttataatatt aatttctatg ttctttaact cattattaca tgagcagata
      361 ctaagattta atattaataa acttcaattt atggttttta tattagttta tttttttata
      421 tttgcattgt ttatatataa gttttttata aaaaaagaga gttttcatat agtctctttg
      481 attataggta tgtttttgat aataatcata caaatcccac aagttttatt aacgatttta
      541 cacaatttat tcagtattgt ttatggacaa tttcaattag atatatttat gtttggaaca
      601 cttttgactt tatatacaat aattattatt atgtattata aagaaaatca taaaaaaaca
      661 agagattaat acctcttatt ttttatacta tcttaaagtt tatataaaaa acttttatat
      721 ttaataaccc tggaataggg agttttggca atccaatata aaattgtatc aaaattaagg
      781 ttttgtgtta taacagtaaa agaaagagaa ctatattcta tttagtgaca gaattgagtt
      841 cgtaatttaa aataaaaaat tatttaaatt ttttgaactt gatttttaaa tcgaattcct
      901 agccactctt gccggagtgg ctttttaaat gcctaaataa tttacttaat aagttatatt
      961 ttgtattctt ttaatataaa aatgtgtgta atagaagatg aatacattaa gttaaaaatg
     1021 tttaatgtac aactaactat tttattaaat ttaactttta tgttattgca tttttcttag
     1081 atttagcaag agcattataa tttatttgat aacccaactt tcataatatg aacgatgtaa
     1141 atcttctatc cattgtgata ctaataaata ttgctttcca taaatggaaa tagtgtaagc
     1201 ataatatcta ttgtagtttt tttcatcttt tttcaattca ttaatattac catctttagg
     1261 aacttctttt agtacaggtt tattttcatt aaacacttgc tttgaataac tggattgtgt
     1321 catcttatca atttcttcag ggctaatttt ttcttcttca aaaagatgtt tcatagttac
     1381 ttgaactaat ttcccaatct ttaattcctt taatgtttca tctgacaaat ttaattcaac
     1441 tgcatctttt aaagaattag atttttttat tctttgttgt tttacaacat ctcgactata
     1501 tgaaaacata ctgtacattt gataacttct taggaaaagt tctgatgtgt cagagattcc
     1561 atcactagca attaagattg gttctaggat tttaccatta aattcttcat tcgcaattaa
     1621 tctagtttta aatctcaatc ctaaagactt aaataggtca ttgacttctg ccatcttagg
     1681 ttctaattca gttataatag ctggattaat ctttggagat gcaaatataa tttctgcttc
     1741 atctaagtcc atataaccat aaatacacat tgctgtacgg atacatttct ttataaccct
     1801 tgtaacagtt tcatttttag atccataatt aagtcctgct tcatgaaaag ctacatctat
     1861 agcataaata tgatttcttc cattatctat tgaaatacct aatacatcaa cttcagcttg
     1921 cataattaat tgctccaatg aattattttt atatatagga tatccatatt tctgctcaaa
     1981 atattgttta gttttttcca taatttctag tattttatca gcattcttta aatcccattt
     2041 agatgacact ttccagtttg tttgcactat ttggcattct ttaacatgac gtagccaaga
     2101 atacaacagt gattctccca tttcaatctt catagaatta ccatcctttt cagtctatta
     2161 tctattaatt gttaaactat atctaaattc ttccatcata tcttcaaatc atgtaatctc
     2221 ttatttgtta tcaaaatcct tgagtcttat acatttacat accttgttag gtaatattct
     2281 attttagata aaagtattta tgcattgctt atcttttagt ttacctaata ttgacaaaat
     2341 tcttttttca cataaatcca taaattcatc aaatttatta tcatcaaata aatcaaaata
     2401 agcatcatta aaatttttga aattaggaca ttccatagta ttattataaa tgtattccca
     2461 acaaatccac catccattag tacgtgaacc atcatcattt attaattctt ttatttcatc
     2521 atcacttaga atctttccgc taggtttttc tttatataac gtacaaaaac ctacaaatat
     2581 atgatgatct atttcaattc ttagtaaaag atcaacatct tctttatcta gactttttat
     2641 aaaataatta attgctggat atgtagagct tttcttatta taataattat tcactaaagc
     2701 ataattattt tctttgtatg agtaatatgg taatttatat ttatcttcaa atttcttatc
     2761 catacgtttt tcaatttctt ctaaaacctt ttttatcatt tgtgttttac ataactttaa
     2821 tcctctttca atttctattg ctactcttat attttcttta gatgataaaa tttctactat
     2881 ctcatcctct ttttctagtg atgatacatt tgtcatattt cttattacct ccataaattg
     2941 cagtataatt tctcttattg gagctatttt tatagtttca tgatgtgaga cacatttatt
     3001 tagccaattt aatatatcta tttcaaaaga tatttgagta acttctttat taaatatact
     3061 attatttatt taaaacgagt tgcagttgtg tttttaataa ttataactgg attattcaca
     3121 ataactatga gtgttgatac ccttagaaat caatttatca aaattgtaat agaaatttat
     3181 gaagatttaa cagaatttat tttttctaaa gatattcaaa ctgataagaa tcttgatttt
     3241 atattaaaag aacccaaata tataccaaat ggtttcaaag aggttgaaaa agaaaacaca
     3301 ttacaaggta tctttattcg ctatgaaaac aagaatggct ctgaaataag atatcgttcc
     3361 aatcaaattg attcaaatac agtaatatta gatacagaga atgcaaaagt cacagatatt
     3421 atggtaaatg attatgaagc taaatatatt gttaaagaca atagtattac aattttttgg
     3481 aatgatgaag aaaatgtata tacaatatat tttgattatg ataataaaaa tgatttaaat
     3541 aagtataaag ataatcttat agatattgct gaaaatataa aataattttt ttcaaaaagt
     3601 gtcacaaatc accttttttt tcgttatatg agtatataag aaaaaaggag gtgatatttg
     3661 tgtatttaaa aaaagtgatt gtagcaggat tatgtacatt aacttgccta ttacctttaa
     3721 atgttcaagc ttttgaagat acttcattaa atactaatga ttataatcaa acaaatgata
     3781 atgatttatt tatgatttat attaaaggtg ctggtagtaa tttgagtatt cgttctggaa
     3841 aggctcatat atcttgttat gttgatggta aaattgggag tttaacatca attacagcaa
     3901 gactacagca aaaaaaatct ggtaagtggg taactatatc aacatggtca agctcaggaa
     3961 aaacttcaag tactttatct agagaatata gagtatcaaa ggggtattct tatagaatat
     4021 taacaacaat aaaagctgga aatgaaagta ggaatataac aagtaatgta acaaattatt
     4081 aatttaatta aaatttagga ggaatattat tatgaaatat tttaaaaaag taattgcatt
     4141 aggactatca attgcattgc ttattccagt aatttcaatc aatgcattag aaaaaaaaga
     4201 cacaaatgta aataaccaaa taataaatgt tatagaatca aatgtatctt ataccaaaga
     4261 gggtattgaa gtttcttctg acttgaaaaa tgatttgaaa gaaattaact tagaagatat
     4321 taaagaacaa atgatagagc aaggaattga ttcaaaattc ataaataatt ttaatagtga
     4381 cgtaatatat agtttagtta aagaaaatat agatgatata aatgaaggag taaaaaataa
     4441 aactcttaaa attacacctg aggaagatat tataaacaat acagacaact cattttatgt
     4501 acaaggaggt tctacatata ctcaaaaatt ttcatgggga gtaagacaaa ataaaagtac
     4561 tgcagcagca aatagatggg tttatgattt gaataagtct tcacaaggat ttgtagcaac
     4621 aggagcagta agtgttcttt taggttctat gggagcacca ataggatttg tatctggttt
     4681 atcagctgca tatatgggag gtcttgcaaa taaagtatct tatgtaaatt cacgaaataa
     4741 tagaggaata actgtggata taaactggtg gttaacttat gcagtaaaaa atcagtaaaa
     4801 attaggtgaa attaatgagt gaaaaacaaa acttaaatta taaaaaaaaa atcttaaaac
     4861 aataatattt atatcttgtt taataatttt atctatattt atagttttta ataatataaa
     4921 atctgactgt tggtatgtta attatatgaa ttatagtgat atgcatgaaa tatctagtgg
     4981 gaaaagtcaa aaaatagcat tgatagattc tggtatttca aaatttcaaa aggtttataa
     5041 aaatataaat ttaactaata gcaataatga ttatgataca aatggtcatg gaacgatgat
     5101 gtattcaatc ataaaaggtt ataataaaaa taatcaaacg attgaaggaa tatctccaga
     5161 ttctagaata atattaatta aagtaatgaa tgatgatgaa agtattaatc ctaatgtaat
     5221 agaagatgct atagactatg cattaaatga aaaagtagat attattagtt taagtttagg
     5281 atccacaaaa acagatatta atataaaaca aaaaatagat aaagctaatc ttaaaaatat
     5341 aacagttgta agttcagcag gtgattataa acaaggattt ttgctatttc cagcatcttt
     5401 aaataatgtt atttctgttg gtagcataga tgatagaaga gatatttcaa cattgacaaa
     5461 tgcacctcaa aagacattaa taaatgcacc tggagaaaaa ataaaggtga tagataataa
     5521 caataatgtt ttctatggaa agggaacatc agaagcaaca gctattatta caggttacat
     5581 agcgttgatg agagacacaa atatttctag tactcaaatt ttaactaatg aaaaaattat
     5641 gaatttatta tcccagataa acaaaaacga aaaaacatat ttaggagcat taaaagaaat
     5701 cagaaaaaaa gtatctgtaa gtacaggtgc ttttttctct tttgatttat catattaaaa
     5761 atagtgagaa atattttact tgaataaatt ctatttgttt ataattatag tatgcattta
     5821 aaatgagggg gaaaatagta tgttctataa caagcaaatt aaaatattaa ctttattaat
     5881 ttctatctta atagttttaa tatcagcact ttcttgtact aatattatta aaaattttaa
     5941 tttattaaaa ttttgtttaa tattatttgg agtggaacaa attttactag cttataattc
     6001 ttataagctt aataaaaatc taatggagac acttttatta tgtattattg gaataatcct
     6061 tataggtatt tctattgtaa ttatgtgaat ataaataaca cgttttgaat ggaaaattat
     6121 attaatttag ttcactaata ttacatcttt aatgcaagta gagtaaagta ttttgaataa
     6181 cataggtcaa tataaattgt aggagtgatt ttcaataata tgtatattca aagtaacttt
     6241 tctatttttg ttacttgcag gtttttatct tgaacaaacg tataaatttt aataaaatat
     6301 aaaaataaac tttatatttc aattacagat gatgatattt tgattgataa taaatatatt
     6361 tttagaggca agaatattaa aaactatatt aaatttaaag atataacagg tgcaaataaa
     6421 caggatagtc ttatatatct aaaagcttta agcattgaga gagaagaata tctaataaat
     6481 agactaaaat catttttctg atttcatata ttttaaagtt ttaattaaaa gggttgcaga
     6541 tattgagtta caaggtcttt tttgtaatat aaaaaacacc actttgtgct cattacaaat
     6601 ttcaatactt tctgtatcta aaagtattga aaatactcaa tttattttgg aattttatac
     6661 tacacatgca taaaacaatt ttaaaacaat tgcaatatta attcattttt tttctaccat
     6721 attatgattt gagttgcttt ttttaattat agaatttcct aattttaatt cattctcaag
     6781 atttgctttt gaaagtttaa gagattctaa tttatcatct tctgtaaact tattctttaa
     6841 aatttcttgg agagataaga gttcattttt cttaaatgaa tatttttctt taaaactttc
     6901 taatttattt gaactaattt tattataatc catgaaatat ttaattagtg ttttaggact
     6961 ttttgatgta gaaaattcaa atttatagtt attacctaga gaaatgaatt ctctaacttt
     7021 attgtcaaat gtaaattctt tttcataaat tatgttcaag ccatatattt cacctaaaat
     7081 tcctactttt ccattattta ttatatctga cagagcttct atagcatctt taatatcaat
     7141 ataagtttca ttatctaatg ttatcttaaa ttcattaaaa aaaattagaa aaatacgttt
     7201 taatatcttc ttctaattta gaaattgata tctttaaagc atctattgaa ttttcggttg
     7261 attttatgtc atttaaagta agtaaatttt gatttaaaaa ggctttttta tttatttcaa
     7321 ttatctgaat ttctctattt atctcacata attttaatat gctatcatca gaacaggcac
     7381 atgcctttgt ttcagcataa ctcataagct gattacctat gtcttcagca gtcctagaag
     7441 atgaagaatt attaagaatt tgagctatat attttgcctt tatttctatt gtctgtcacg
     7501 aatatgcatc aaaagaacct tcaactacat acctaaaaat atagacctct ttattcaaat
     7561 ttccttgcct taatattcta ccttctcttt gtgaaattga tgaaggtttc caaggaacat
     7621 ctacatgatg aagtgatttt agaggtagaa ccaattaata ttctaataat accattattg
     7681 aaatcatcaa taagtttctt tcttttttct ggagtattag cgtcatgtat gtatgctata
     7741 tctttttcta aaacattatt ttttagaagt tcatttttta tatcattata aacattatgt
     7801 gaatttccat taggagttcc tagatcacag aatactagat gtgtacttat tttatcctca
     7861 tgatataaag aagctatatt ttctccaact tttattatct ttggtaatat accatcaatt
     7921 ccaactaatg cagggcttac agccatcaaa cgaccatctg tagttacatt taacatgtta
     7981 tctattattg gatcatatgg gccttcatga attttttctg cacgttttac aagagaatct
     8041 atatattctt tcatttggtt tgtaggtttt ataatttcta ttataggttt tccacctttt
     8101 atctgaggaa tatctaaatc atttatgtca cagatgttaa ctacatcagc aatttgtctg
     8161 aatatattaa ctaattctgg aacattacag aatttagcaa atctttgctg aaatctaaac
     8221 ccttgaccag taggatctac ttccattgag gatataattg aaccaaattt acttgcccaa
     8281 gcattgaaag tatctacttt gtaatacttt aatgtatctt tatttaaata agtgagtaaa
     8341 gtatacattt cacatatact attagaaata ggtgtagctg tggcaaatgt aacaccttta
     8401 tttccatgaa tagatttaaa atatcttagt ttgttgtata aatcctgtgt ttttttagtt
     8461 tttaaagttg atataccagg gacttgcata gttgtattaa aatataaatt tttgaagttg
     8521 tgagcttcat ctatgaataa gtttgttatt ccaagctttt caaatgaaag aagagcatcg
     8581 tctttatgca tatcatttag ctctttgatt ctatttagat aattttcttt cattgtttca
     8641 agtcgttttg tagaaagatc agggcattct tttttgtaat atttaagagt atcatttaat
     8701 tcttttaagt ataagtctaa taattttaat tctgtatcag cttctaaagg gattaatcct
     8761 aataccgaat gtggaattat tatactatcc cagttgcatg tcacaatttt agctataatt
     8821 tttcttctat tggatttaga gaaatccttt gaagttgtag ctaatatatt cgcttgagga
     8881 tataaattaa aatactcttt agcaaattgt ccagattcac aaagtgaatt tggtataaca
     8941 aataaattct tattaccttt ctttgaatct attttagaaa ttctatttaa ttcttgtgca
     9001 gctgttatca ttgtataagt ttttccagaa ccaacactat gacatagaag agtattacga
     9061 tcagaagtaa ttattctact agccgctttt aattgatgtt ctcgtaattt tatattagga
     9121 tttattctaa catcatttaa tatattttta tattcctttt ccttataatc tataaacatt
     9181 tcattgtatc tatcaagtaa ttctttatga atataactat tacttgttac atagttatga
     9241 aaagctataa gccatttatt taatatgttc atagcaagtt gagtttcttc caaattttta
     9301 acagaaactt ctttaccatt ttgatattct ttatcagtga cagttatagt tttcatattt
     9361 aattctgctt caacaatata caaagatttt ctcctttttg taccccatgt aaattcattt
     9421 ttacttatag gtataatgtc agaacatttt actgaataac caagttgtgt tgaatacaat
     9481 aattgaattg aattttcttt gagttctaat gttttttcaa taaaatcaga ttttatactt
     9541 gaagatatcc aagtagaatc aatgctaaag aacacatctg tttcatattt aggttgatta
     9601 gcttctaaag ctttaacatt aaccaggaaa gtattatctt ttattgatgc ttctttggct
     9661 atttttaatt tttctttaac atatccactc aaataattat ctctatctac taaatatcct
     9721 gtcaaacggt caatataagc aagttgttta gataataatt catttttgat attatgatat
     9781 gattgattca tgatgctaca gatataatca atatttaaat atcctttgta ctatctaatt
     9841 ttgagtaaaa taatgtaact tctttttctt cattattttc cttagattta aattttttta
     9901 aaacagtgtt tgttccagct ggatatttta cttcaaatcc tagattgaat aaaaatctcc
     9961 ttgttttaag aatattttgt ttgttaattt cgttaaagtt tttaaatgtt tcacctaatt
    10021 tttttgatag agtaaagata aagtttttga tttcataaaa acctcctttt attttttatg
    10081 ctaatagtta cagcttattt ttatttgcta aagtatagct ttaatttaat ttgtatataa
    10141 tatggggcat ttagaagtct tttttgaaaa tttttataaa aaatcaaaaa aactgttatt
    10201 aaaatgattt ataatcactt aataacagtt ttaattatta acattatttt ttatagtaca
    10261 aataagaatg tataatctaa aaacgtttaa gaattagtat tttttagttc atatttccag
    10321 gtttcaccac tttttatttt ttctctctca aaataatttg gatatataac aataggaaaa
    10381 ggaggcttat aaataggagt aatattattt aaagtacaat aacggatgtt aaaatcttca
    10441 tatcttagag tgttatcttt tgtaatccag aaaaaatctt ctacactcat agcaagatta
    10501 cttctacaaa tatcccaaac gtcataatat cctagtttaa attcttttag tataaaagga
    10561 acctctggtc tgcattcttg aataactctt tcctcaatcc aaattcttat aaattcatcc
    10621 catttatcac tatctaaatt cttgaaaata tttgtgattg gaaatgggtt cattcccttg
    10681 taatttttat tttgcttaaa tgagaattta tcatttatta tattatatat taagattcct
    10741 gccgtatcgt ttttatattt taaaaaatat aagtcgttat ttctgattac tccattattt
    10801 ttgatgatta gtttatcatc aaaatttagc ttatcataaa ataaattatt catataaaac
    10861 tcccctctct tttaaatatt caattcttac ttttaacaag tgtttaatac attttaatct
    10921 atgttgtctc aaaagatctt tatatctatc aaattgtccc tagaaaatag tatttttata
    10981 cccttatttg ttatacataa ttttatttag aagataaact ttatataaaa caattaaaaa
    11041 tatttctatt aagataaata aaaaagagct atctcagaac aaatttaatt tgctcatgtg
    11101 acactatatt ataaaataaa aaaattttca cactattttt tacactatat aatttctatt
    11161 tttataatta aacccaattt ataagatata gaaccatatt tatattttta tctcttgatt
    11221 tgttttaatt acatatattt attttttatc ttatttaata attactatta cttgaatatt
    11281 tacttctttg agtaaatttc atagctaaca aagctaaaac tattattata gaggtcaaaa
    11341 tacaaatata attcatatta aaaaagcttc catctctttc ttctatataa gtcacaaaac
    11401 taataaacca ccttacaggg cttataatac taattttttg caacatttct ggcatttttt
    11461 caactgagat gaatgaacct ccaataagtg ataatacaag tgatatacat gtagaaaata
    11521 aatttgcatg catctctcta ttgaataaag aagatacaaa tgttccaaaa gaagttgcca
    11581 aagctactac ccatattccc attaaaatta aatctatata atccatacca atatcaatat
    11641 taaataactt aattatagat attgaaacta tgtactgaaa atacgttatt gtaaagttgt
    11701 ataacatatt ccctagcaca tatcctctta cattttgtgg agaatacagc actcttgtaa
    11761 atgtacctga gtttttatct ttaataatca ttgatgctgt tacagtagat gttatcatta
    11821 aaaataatac gataaatgca attattcttt gtaaaactcc taaagtattt tcttgtaatt
    11881 tacttatatc tacaggaact gggtcttttt tatatgtttc tattaaatac tttaatgtat
    11941 cattcgtatt tttatttttt atagaatata acttaaaacc attcttatta aaatatatga
    12001 cagctgaata cttgcctgtt ataatatcag ttttaattgt tttaaaatct gcaatctttg
    12061 tattaatccc ttgagtattt tctaaagcca ttattgtatt ttcataggtt cttttttcag
    12121 attcctttag aactcgttcg tttttgtact catctaaaat accaatatta aaaaatggtt
    12181 tacttatgta atttgccaat actcccaaaa ttactataat tataggaaat aaaagtgtaa
    12241 ctaaaaatac tattctctta tttatatttc tttttaagtt aatattaaaa acatttatta
    12301 cattcactat ataaagaccc cctttttaaa aaacttgatt gtaagtattg tcataaatat
    12361 gcttacaact acaaatatgc atgatatatt aaaaaggagt tgtaaattat tatcatagat
    12421 acaagcaact atgcctctat taatccatgt taatggtgat atattaatga ttaatgaaat
    12481 aactggattc aatgaactaa ctggaaagaa cactcctcct aagaatccaa aaataactat
    12541 cggtatatta ataatattac gtaacatatc taaattttta caaacaagac ccaaaaacaa
    12601 ccccatagat actaccacaa tagattcaca cattaaaaag aaaagaacag ctaaaaattt
    12661 tccaccaaaa ctcatacgaa aaatacattt taacaccact aaagttacca aattgcatat
    12721 cgaaagtact gctgtacaag aaaaaagttt tgaaataact aaatctacta ttgaaatagg
    12781 agaaatcata taacgatatg atgtgttaga aattttttca tcttgtcccg catatgaaac
    12841 actaataatt cccataagaa cacaaaatgg tattgtaaca atagtataat aattatatga
    12901 tgtaaattcc tcaccatagg actttgatgt caaatatcct aataacatta tgattattac
    12961 tggaaaaaca atattgtaaa acagaataaa aaaatcttta cttcttcgtt ttattcctaa
    13021 tttaaacaat ggtaaaaaac atctcatcta tttattcctc caagtctctc aaatctgtac
    13081 ctgtaagata taaaaaaata tcttctaatg tcttacaacc aaattctaaa tatttatttt
    13141 tatataaact cttgtctaaa tcttctataa ttattccttt atctattaaa gcaattctat
    13201 tacataaggt ttcaatttct tccatataat ggctagtata tataactgtc gtaccattag
    13261 tattaatgca tttgattgcc tccaaaattt tatttcttga ttgagggtcg atacctactg
    13321 ttggctcatc catgatgaga atctttggac tatgtgcaat tgcacaagct atgtttagtc
    13381 tacgtttcat tccaccagaa aattttgatg gaaactcctt atggctttcc caaagaccaa
    13441 caaattccaa agcatcttta gttctctctt taagttcatt ccctttaaat ccatataatg
    13501 agcaaaaaaa tttaacatta tcatatgcac ttaaatcttc atatattgct aattcttgtg
    13561 gtacaactcc aagtgaactt ttaaaaatat tttgttgatt cttaatatct tttcctttat
    13621 agtatatgct tccactatct ggagacacaa tcgtagtaag catattgata gatgtacttt
    13681 tccctgctcc atttgctcca atgaaaccta aaatatcgcc ttccaataac ttaaaacttt
    13741 ctattgacac aacttcctta ttgttatact tcttagataa atttttaatc tctaacaata
    13801 tattactcat ttataacccc ccaatattta accaacatta tatatccaat attgtatata
    13861 taattttttt aaaacacgag tattttaccc gtgttattgt aataaaattt attacttatt
    13921 ttgtaatttt agtattatct tatctatgtt ttctatagct ttatctgggt tattaattat
    13981 ttcatctcta agtctctgaa cttctaataa ctcatttgtc gtatcagatg taaataaaaa
    14041 atcttcttct atatttgaaa aatctataga tttaattata ttctgtgtct cgcaaccaac
    14101 ggatatatac ttatcaatat catttaatat ttcttcatgc cataaaattt gataattcag
    14161 attatctata gtcatatcaa atgcaatttt ttctgttgca agactctttt tatcaatttt
    14221 tttaatctct ttccaatttt cccaatactt cttctgctct ataagatatt ttatatgttt
    14281 ttcaagattt ttttgcaaag tatccttagg taatacatcc aaaatattat gtaataggaa
    14341 tttatttgaa ccggttggaa ctattggcat ctgaagctct ttttgtattt cttcccttaa
    14401 ttctaattta ccactttgag taatctcata gattttacga atcctagctc ctgttttttc
    14461 ttcttttaaa actctaacgc ctccatcttt ttctaatttt gccaatgcat aatatattga
    14521 cccagattgt attttagtcc atctatctgc accagatact tgtaaaaact tttgaatctc
    14581 atacccatgt gttggcttaa tatttagata atataaaatt aaagtgcgta tcataaaaat
    14641 ccaccaccta tactctatct tggatattat attatcacca atcttggata tagtcaatag
    14701 ataacatagg atatattaca acttattatt tttattattt aatacaagga gttccatgag
    14761 acatacatat ccattcatat tctaaattat ccaattctct tatagatttc atcatctttt
    14821 tagaatccca attccaggga ttagggtaag aaactatatt tccattcttg tttttgacta
    14881 aatcacctgc aaataataca tcttcaaaaa tcatgcagac atgccctgga gtatgaccag
    14941 gagtatggat aatttttata ttcccaatct gcatattctc tccataaggt tcaacatcct
    15001 taatgagcct tcttgaaatt gtctttccaa taaacttctt aaacccaggt ctatctttct
    15061 ctcctataat aaaaggtata tcttctgtat gagcccatac ctttgctcct gttttctctt
    15121 ttaataattt aatattagac atatggtcaa catcatgatg agttaataaa atatgcttaa
    15181 tatctgtaag tttgatacca agtgttttta attctttaat tatatttttc cccataaaag
    15241 gaagacctgt gtctataaga gtaatctctt tatcaaacac aataaaacaa tttgagccac
    15301 gagtactatc taaccttaat acattttctt ttattttcat aaataaattc cccctatttg
    15361 gtattttgcc tatataatta attaatgaag ttataaatag ctataatact tgatattaat
    15421 tttattttca ttaaagtata ctaatagtat acaaatatat tatatttaca caagtatacc
    15481 accagtatac tttattatca atagaaagga ataatttata tgtcagaatt atcaaaaaga
    15541 gataaagaaa aaatacaaag agaaaatgaa attattgata aagcagaaaa attattttct
    15601 cttaatggat ttgataatac aactatgaat gagttggcaa aggaagtcga atatactaaa
    15661 cgcaccatat acaagtactt ttcatgtaaa gaagatttat tctttgctgt tgtcttaagg
    15721 ggatataaaa gactttggga taatgttaaa atagaaagtg caaaaggtaa aacagggttt
    15781 gaaaaaataa aactttcata ctttgctttt cataaatttt actctgtaga accttctcta
    15841 ttatgcctta tgggaatgat tggtattgta aactctaaaa aatcggatac tgagatgctg
    15901 tttaaagaaa agtttttttc ttttaataaa tttatgtttg atgaaataca agaaatgttt
    15961 gaaattggaa aaaatgatgg aagtattagg tatgatattg aaatatctac tcttatgtat
    16021 tcatcaatat ttacacttac aggatttttt aatttattgt ctgtaacaag aaaatcatac
    16081 ctgaacaatt ttaatataga tgaggaaaaa tttattgaaa caacccttgc cattttaata
    16141 gactcgatta aagcatagac ctaagtatat aaattaaaat ttatatactt aaatggtaat
    16201 ctttactata tataatataa aaaatattaa gcataaaact aataatttaa attaatgaaa
    16261 ggactaaaag taaatggcta aaatacttct cttagaagat gatgatacaa ttacgtttgg
    16321 gataaagact tccctggaaa ataaaaatca cattgtatgt tgttataata cgattgctga
    16381 agctaaaaaa aattttgata aaactactga tttaattctg cttgacttaa atctacctga
    16441 tggtattgga tacgaatttt gccaatacgt taaaagtata gaagatactc cagtgatatt
    16501 tttaacagtc cgtgatgatg aaaaagacat tatacgtgga ttagatatgg gtgcagatga
    16561 ctatgtggtt aaaccatttt tgctttcagt acttcaatct agaattaatg cagttcttag
    16621 aagagctcat tctaatacta ataatactat tacttgtgga aatataagtt tgaataaagt
    16681 tgaagtcaag gcatatttag atagtgttga agtacctctg acagcaggag aatataagct
    16741 tcttctaagt cttatggaaa ataaaaatag agctatgact cgtacaaaat tactagaaat
    16801 gctctgggat gtagatggta atttcgtaaa tgacaacact cttactgtta caataaagcg
    16861 tcttagagaa aaattaaaaa atccaccttg tataaaaaca ttaagaggta taggatatag
    16921 aatggaggac agctagtgaa aactccaaga aatatcaaca gtacagttgt ttttataata
    16981 ttctgcttaa ttgtaacttt tttattgagt gtaattctaa caactatcac ttcttttaat
    17041 gaatacaatg tgctgtctaa ggttcttgat gcatcatatg agtacaatcc taaatctaca
    17101 gaaagtatac taaaatcact gaaaaattct agtgatgagg attttaaaac aggaaatgaa
    17161 attttatcaa aacatggata ttctaaaggt acattttgga gtaaaaactt tttttatttt
    17221 ctagtggtat cgtttggtat aatttcaaca atggctatag ttgtatatat aatcaagtat
    17281 agaacaaata agcaaaaatt gagtagaata aacatgctta ctcgatactt agaagaagta
    17341 aatttaggaa aagagtctgt acttttaaga tatgaagatg aattttctta tcttgaagat
    17401 gagatatata aaacagttgg ggaacttcgt tgttcaaaag aatttgctct aaaagaaaga
    17461 caaactcttt cagataacct tgcagatatt gctcatcagc ttaagactcc aattacttct
    17521 atgtcactta tggcacaatt actttcagaa aattgtccag atgaagaaat agattatatt
    17581 aacaggctta caaagcaaat atcaagactt gagagactag tttcatcttt acttacctta
    17641 tcaaaattgg atgcgagtac tttaatattt gaaagcaaac ttatagatgt acattctctt
    17701 cttacttatg caattgagcc tatagaaggt tctttaagag aaaaacatca gacatttact
    17761 atcaaaggtt ctccttcaat agaatttgaa attgatatta attggacttt agaagctctt
    17821 ttaaatattc ttaaaaattg tagtgagcat atagaagctg gtggacatat cattgcttat
    17881 tatagtcaaa accctctata tgttgagatt atcatagaag ataatggtaa ggggtttgct
    17941 caggaagagc tcccatatat ttttaataga ttttatcgtg gtaaaaacgc tagtaaggac
    18001 agtattggta tagggcttgc tctatcaaag tctattatag aacgtcaaaa tggtactcta
    18061 catgcagaaa attgccataa tggtggtgca agattcataa ttaagtttta cacataaaat
    18121 actggattat aggtaaaata cccataatcc agtcatatct atatcctatg ttatttatta
    18181 ttttagtaat ccgctattta tatctaagat tttattaaat aaacaattta actatctcta
    18241 tactcgtaag tattcttgaa ttgaaaccat aaataagttc agataacttt tatttatatt
    18301 gtttcacttt ttatagattc tactatattt tcattcttca actgattgta tcctgtcata
    18361 tatgatgcta ttacaataaa aagtatcaat atagtaaaac ctattattgt agatataggt
    18421 gcaaatggta aatactctat aaaatatatt tcatttatac gtagaaaagt atatactatt
    18481 cctatttgca caggaatact aagtagtaat ggtgtaattc ctaagaataa accttccaaa
    18541 acaagcatct tttttatgcc atctggagat aatccaacag aacgcaacat agcaaactct
    18601 tgtcgtctac ttctaatatt tcctgacact gtagcaagta catttgataa tccaatcata
    18661 gccaataaac ctgtaataaa acctactatc aaattcatag tctttcttcc actaccattt
    18721 tgtttttcat tttctacaac atcctcaata ctatagtctc ctgaaccata atctttatta
    18781 caaatagact ctaattttcc tcttactcta ggaatatcct cacgattatc tactttaaac
    18841 aatcctatca gtctatttga acgtgaccta cctacttcag cataattttt agatatttct
    18901 tgcaccatag atattggtac tatttgcatt aatgtatatc ttgaactagt atctattatt
    18961 ttaggaagtg tgcttgtaat agctcccact ttcatgttgt aagtataatc ccctttatct
    19021 tcatcatata ttttttcatt taatttaatg ttatctccta ttgaaagatt taaataatct
    19081 atatatactt tatttctacg tgtgctacga ttaacatctt cctccttatt atatacaatt
    19141 gaagttggat tttttgtatc ataaaataat tttgggtcta cagagatttg tctgcaatat
    19201 tctgcgaaac tctcatcatc aagcccaatt atatttgaaa ttatacgaaa cttgccatca
    19261 cgctctatag gagagtactt tttagatgaa actatacttt taaatcctcc atttttcgaa
    19321 agttcttttg aagcatcttt ttcagtcagc caagtggtag cagacatctt ttgataatat
    19381 agtgagttct ttacaccttc tgtattatct aatttttcaa tgaaatcaga ctctacaggt
    19441 tcactatttt ccaaataaac ttctatatct ctttggtctt tataattatc acttccataa
    19501 acagcttctg ctccttcttg atttgcaatt atatgcaaaa aacctgtcag taataaaaaa
    19561 gataatgtta aagatattgt tgcagtacga taagattttt tacgagcacg tagtgcattt
    19621 gatgcaagtt ctccttctat tccaaatatc tttcctaatg aatatttatg tgacttttta
    19681 attttaacac tatctccttg tcgtattgct tctataggag atatttttga tacttttcgt
    19741 gctggtatga gtgtagaaat ccagactgtt actattgtaa gtaaaactgc tggcagaaaa
    19801 gcaggaatac cataagtgaa tactacttct ggagcatcag tatgataatt aactgaatta
    19861 atatagacta taagcttatt acacaataac caccctaaaa ataaacctat tggtaatggt
    19921 ataatagtca ataaaaaacc ttcaaacact acagaccttt taatctgttt tggtgatgct
    19981 ccaacactag ataatattcc taattgtgta agtctagcat ttgcagatag tgaaaatgcg
    20041 ttgtaaatta ccattacaaa cacggctact gtaaaaattg ctattgtaag atacataata
    20101 ggagttgaaa attttgatat attgctcata gatgctttct gttctggaga aaagactaac
    20161 atttttaaaa gataattact attgtattta agattgtatt ttccatattc attagtcttc
    20221 catcccaatg atttagcaag ttttggaagt tccttatatg tgtctcttat atttttaaat
    20281 cgcaagtaca cagttatact gtcattaggt tttatacttg ttttatcaag atatccaaga
    20341 gctgtatatg caggtacaac tgatgaagta gcaacatcta cctttcctac tattgtcaat
    20401 gtagtctttg aaattttttt aaaactttcc cctttcgatt ttggggctac aggttcaaga
    20461 ggctttccat ttaggattct atctcctatt gggagagtaa ttttatcacc aatttttaca
    20521 cttggattat tctcaaaata ttgttttgat agtgcaattt cattagtatt acttggtcga
    20581 cgcccctcta ttatagaatc tttttctggc atatgattcc aatactctga tgtagcattt
    20641 ctataaacta tataatctct tttgtcatta ttaattttgc ctacatacca ttgtcctttt
    20701 accattacat catcaactga agaaaaattt tcaattaacg ataagtcttt tccataagta
    20761 tcgtcaaaca attcaccatg ccagttaccc tctttctcaa ttgaaagtct tataaaatct
    20821 gtccacatgg tatacaacaa tccacacaag gaagacatca tggttgtggt aagtaatatg
    20881 gctaacatta tagctatact actacgttta ttgcgtcgta caaagtctaa ggtatattct
    20941 tgaagaatat tcatttcttc accacctttt cagagacaat cactccatct tccatagtta
    21001 caatacgatt tgcctctagt gctattttct catcatgagt aataagaagt attgtctgat
    21061 taaatcgttt atttgataag tttaacaaat ctacaatttc ttctgaattt tttctatcga
    21121 gattaccagt tggctcatct gctaataaaa tagttggtct atagattaaa cttctagcta
    21181 tagataccct ttgttgttgc ccacctgaaa gttgacttgg aagatgattc aatctatcag
    21241 ataatcctaa tatagataca atctcagaga atctatcttc atccaccttt cttttatcaa
    21301 gtaacatggg taataatata ttttttctaa catcaagagt aggtataaga ttataaaatt
    21361 gataaataag acctactttt ctacgtctaa aaactgcaag agcttcttca tttaagcttg
    21421 atatttctgt atcttcaaca taaatctttc cagatgtagg tctatctact cccccaagca
    21481 tatgtagcaa tgtagatttg ccagaaccag atgctcctac aatggataca aaatcacctt
    21541 tttgaactga taaatttaca ttattaagag ctgtcactct ggtttgattt gaaccatata
    21601 tttttgtgag attttcacat tttaatattt ccatatacac tcatctcctt tatggttaaa
    21661 ttttagcaac ctaaaatgac attatagtga catgaataca aatatcgatt actattaaaa
    21721 atattgttta gtttttgaac attatttaaa attataatac aaaacaaaaa ctatgcaata
    21781 tattttattt atacttttaa tatattgcat agcctttaaa agatattaac tttaatatct
    21841 ataagtattc aatttaataa tcaatagcaa gtattttata tactagagga gttttgctct
    21901 atgtaaactc aatttagtaa aattatttaa taaatattta cagactatag gtaaccaata
    21961 tttacaaata aaattaagtt tattacatta cactataata tttcttaatt atattaattg
    22021 caatttcctt tacctttggt cctgcaattt ctttattgga atcatctgat ttaatagcaa
    22081 aataataagt gtcatcttta ctctctagca taccaacaaa ccatgcatct acacgtttat
    22141 tttttccatt aaatcctgtt ccagtttttc catatacatt tatattttta tcacttacat
    22201 ctattttcat aatatctttt aaaatattaa tatgttcttt tttaaagttt gtatctccct
    22261 caaatatttt caccattgtt tgcacttgtt cttttggaga tatttgtaat gaagattcta
    22321 accaaaatcc atttaaatgc ccctttccat tttttaaatc tccttcccat tcactaatat
    22381 cacagttccc atactttaaa tcatctaaaa tactttggac agatttagca tcaaccttat
    22441 ttatcaattt tttgtagtac caaacacaag actccttaaa tgcctcttct aaactaagat
    22501 ttttattcca atttttattt ggataatttg taccatcata cccaataact gatttttttg
    22561 acgttattac ccctttttct aaaccaatta atgttgaaat tattttaaaa gtagaacaag
    22621 gtgaagctct tgtttcaatt aaatctttgt tatatatatt atattcttga tttctgctat
    22681 tataaaaaat agctcctcca ctaatacctt caaaacaatc actatagtta actatattaa
    22741 ctctttcttt tttattgtta tcattattaa tttcagattt atttaaatca gattttatgt
    22801 aattcttatc agttttttga tttatatcgt tatgtttttt acctgcataa tacattacca
    22861 taactatacc aaccaacaag atagttgtcc aaataaaatt cttttttctt ttcataattt
    22921 atatcatctc ccatatttaa atttataacc tacttttaaa atagtagaca ttatttgtaa
    22981 tatacttcaa tctaggtgct acttataaaa aataagacta aaggaataac tatatatctt
    23041 atattttctt cacctagcac aactatgtcg attaaaccta ttacgaaaat aattaggtaa
    23101 ctattaatag cattttgtcc tccttttaat ttgtgatata gtatttgatt ctacttttaa
    23161 aacttactat tgtaatattt aaatattaca atagtaagtt ttaaaagtca agttagtttg
    23221 agaaagttat tttaattgta taattgttat tacatttata aaatatggca catttaaaat
    23281 tattttggta ttggtagtat taatataata aatattataa aagctataaa ttataaaatt
    23341 taatataatt tatagctttt actctttcaa atattatttt ttattgactt attaatcaat
    23401 tttattaaca ggttacattt atataagtaa acacttaaat aataaatata taatctacat
    23461 atctataagc tgagtcaatt caccagtata tgtcaactta agtttgtgca tagctcgtgt
    23521 acaagcaata tacaacaaac tacggtcata gtcactatag tatgttttac tgtttactga
    23581 aggtataata acttcatcaa actctaaacc ttttgacatt ttaatagaag ttatggacac
    23641 tccttttgta aaactagaac tttcagaaga tattaagtta acactatact cttgttttaa
    23701 agcattatat ataacctctg catcactatc tgtctttaat ataataccca aagttgcatt
    23761 atcacttttc ttaaactctt caatttctat ttttatctta gatacttcat cttgtttatt
    23821 agtacattta actaaagctg gttcttcgcc atgtcgttca ataggctcta aagaagatac
    23881 atcttgaacc ttctttgcaa aattaataat ctcaaaagta gaacgataac tcttgttcaa
    23941 tgtaactagt tctccttcat tatatagttg tctcatatca tctagtgtat gagtatgatt
    24001 aggattaacc aattgtccaa agcctccaag aatagtcttt ttacacttaa aaagtaagtt
    24061 tattacagca tattgaatag gagtatagtc ctgcatttca tcaataacaa catgtcttat
    24121 aatcttatct tcttgtatcc cttcatatgc agcatgaata tatataaatg ggtatacatc
    24181 tgaccattca agagttttct ttgttgccat aacaaacata tttgatagat tcatttgttt
    24241 aaagaaatcc ttatatagtg taagagtatt ttttattgtc aacattccat tcaaactttt
    24301 aagtatactt tttaactttg gtaaatcctc ttccataata ttatctgact caaacttata
    24361 atgaatgtct tcagctacct tctctaatct tttcttaact ggatatctat tatatgcctc
    24421 aaatctactc tgtatccagt cacttttagc tgtaaaactt ccaaaattgt agtcttttgg
    24481 gataaaaatc ttatttggca tttgttttat ataataatca ataagtttta caaaatcaaa
    24541 tgtagattta aagcgcactc tttcagccca tttagcatca tttatttcta atgggtcttt
    24601 ctcactttca aaattaataa ctctatctaa ttgtacctct gctatatttt caaaacttaa
    24661 ttcacataat ggctcttctc caagctcggg aaggacattg gaaatatagt ctccaaagac
    24721 tttattcggt gataggataa ttacattgtt tgctgatatt ttatctttaa atcgataaag
    24781 aagaaaagca attctgtgta atgctataga tgtttttcca gaaccagcta ccccttgaat
    24841 aattagtgta tgagctttat catttctaat aatttgattt tgttcctttt gtattgttga
    24901 aataattgac ttcatctttt catctgaagt gtgactaagc tccttttgaa gaatatcatc
    24961 ttgtatatta atggaacttt ctaatgcgta ttccaatttt ccatttttaa ttttaaattg
    25021 tcgttttctt gttatttctc catccaccca tcctattgga gcatcatatc ccgcttttcc
    25081 tatttcataa tcataaaaca tactagcaat tggagaacgc cagtcaagta ttataagttc
    25141 atcttcataa tcaaatgcaa atctaccaat ataatactta gattcatcat ccatatcttt
    25201 tagcctaaaa tctattctag caaagtatgg agaatcttta attttatcaa tcttatctcg
    25261 aacttttacc ataaaagccc catagttatc tatttgtttt agcccctgtt cattttgaaa
    25321 catttcatgt gggtctattt caccacgatt ttttaccata tacattttag tatccatata
    25381 atccttgtca agcttgtcaa caaggttttc agctttctta aaagcatcat ctaacttatt
    25441 atttatatct attagatgtg caatctcatc tggaaaaaaa gttaataatt ctgtatcatg
    25501 ttcatacata ttgtgtttag aattggatgc aatagtatca caatttatca cttgtttatc
    25561 ttcaaacatt taaatcctcc ttgtaattaa gtacttacac tgaatcatta tacttaattg
    25621 tgctttgaag tttttaatta ttcttgctat ttaacttaaa tattaacttt aaaattcatt
    25681 tttctaaaac taaatctttt tatacttata agcataagta tatttacaaa caaaatatgt
    25741 tgaaaataaa aacactctta tatataaatt aattcaaaca aaaaatatgt agtaaacttt
    25801 ttatttaatc tactattaat ttggtctagt atctgtttct tctacagaag gaagaataaa
    25861 tttttgagta ggatacccaa attccacaag taattctgct tctgcaaaac ccaacttctt
    25921 tatcatatct ctatgacctg tatcagcttt atcaccttct cgaaaagtag taattgagat
    25981 atcagtatct atcaaaaaat cttcaataac tttcttcaaa aacacttgtg caatctctga
    26041 attacgatac tgtggatgta ttccaaaaaa atcaatgctt ctagtttctc tattaaacac
    26101 catatttgca atagctacat tattaagttt taatattaaa gctctttctt ctaaaatata
    26161 ctgttctaat tgatatatat attcttcctc ttgcaaattt ggaaatccat ctatgactaa
    26221 tctcactaaa ttcatccata atggtatatc agacatattt gcaagtttaa tttctttttc
    26281 caattctagt acattctttg aaaataagtt atcttttttc aaaacaaatc ttagctgcaa
    26341 aggataaaat tcttgttctt tcctatattt atttggagat tttttataca tagctttaaa
    26401 tatagaagtg aatgcctgtt gactttcata tccagctatc aatgcaattt caattattgg
    26461 tttctttgaa aataccaata attttgctgc ttctgtcaac tttcttcgct ttatgtaatc
    26521 atgcattgtc agaccaacag aagttgtaaa agttctatgt aagtgatatt ttgagtaatg
    26581 aacagcatta gcgactatat ctaaatccag cttttctgat aaatgctcct ctatatagtc
    26641 aatggcagtt atgacattaa ttactttata agacattgca gctttcctcc ttttatccat
    26701 gcaacattat atcaattata acttagttat atttaaatta tctttctatt gatttgtttt
    26761 atcgtgtctt gtagagagtg taaaatggcg tattcagtgt caatcaatgt gccgtctaca
    26821 taaaagacga tttctttgta atccattaat ttctccttaa attagcctaa tcgaaaatca
    26881 ctgtccaagt gtctgtacga catgctttaa agcacatttt aatctgttct tctgtatttt
    26941 tttctgtggc gagttcagga agttcatttt cggagaaata agaaaactcc gtagtttcta
    27001 tattttcttt aaattcaccc ccgataacgg tacaaagaac aaatattttg catactccgt
    27061 aagcgtatat aggtaaattg tgtttcgcgc ggtcttgaat tgcaataatc ctgtcggcgg
    27121 ttatatctaa tccagcttct tctttgacct ctttaatagt attttccttg actgataaat
    27181 ttacttcaac ccaaccgcct ggaagcgacc acttccctgt attttcttta acaagaagta
    27241 tttttccatt ttcaaaaata gcagctctag tatcaagttt tggagtttgg tatccacttt
    27301 cattgcaaaa aagatttctt actttttccg tggatatgtc agttttatat gctataattt
    27361 cggcggaaat ttctcgtatt ctctcatacc gctctctgtc gtatatatct ttcccataag
    27421 ttattccagc ttgagcgatg ctttgcaatt ctatcgccca ttccaaccat ttttcgttca
    27481 taaaatcacc tcccgttttc cgaagaatat attataatta gttactgatt agtaaaatct
    27541 atttttaact actcctgttt tgtatgttga acatattcta taattgtacc atctggatgt
    27601 ctcaatgtca tattatatcc tgtaggaact tttttcttat ctcttactac aactgctcca
    27661 ttatccaata ggtaacttct ccattcatca acagaatcaa ccataaaagt agattttgtt
    27721 tctacaaatg gtttaagagc ctcatcagaa ccagataata ataaaacatt tcctatttgt
    27781 gctagttcca acccaacttc tttataagaa aaacgcaaag aacatttttc ttttaaaaga
    27841 ttctcataaa aaggtatggc cttttctata tcttgaatat aaaaacgtgt taatatatcg
    27901 tatattttca tattttcccc ctatatctct atattattta taaagtatat cactctacaa
    27961 attatatagc aataaattaa gcattacctt ttgagcattt taagtgcact ttcacaatat
    28021 gtttggggta catcagaata cataaattaa atctctttga tattatttag tataaaattt
    28081 atacagtaaa tgtccttatt atcaactaat aaacgagaat cttttacttt ctatataatg
    28141 ggtaacatca ttttcgtaag gtattcacta gctggacgat tgatatcatt taaatattgg
    28201 taatatatat cgccatgaag tttatatcca ttactatttg cccatgaaaa taagtcctct
    28261 aaagtagggt cttgtaattc atagggccct aaatcaattg cagttattat tttctgtgaa
    28321 ggaataattc tttgtaaaat ttcatttttc ccatctatat aagtggccac aggaaaccct
    28381 acttcaacat ccaattctgc taaatccatg ttatgaaaac atacaattgg tgctcctgag
    28441 gataagattc ctctttcctc caaatattta gaaatttttt cgagactttg ctttgaaaac
    28501 tctgaaaact ctaccacaaa gtcaattgtt tttcgtattg ctaaaataca atactcagat
    28561 tgttcagcta ttgttatatt agatattcta gtcattttat tcctccatta ctttattttt
    28621 acctctaatc cttttatacc aaattacaca aaatttcgct gtataaataa ttatttcata
    28681 tgaatataaa acatagcctc cttccatttc ttatattgaa agtataacaa aaataatctt
    28741 atgatgtttg tcacacagtg ctcttatagt agtacatatt taaaagactt gcctaatttt
    28801 aaggcaagtc taaaagaaat cttctttcta taaaaaattt atacaaacaa ttcaaatatc
    28861 gaaatataag ctactatcaa actataaatt taaatttact aatatcaaat atcaaaattt
    28921 aaacaagttt caggctcatc ttctattctt gctattttaa acttacatgc aattaatacc
    28981 agagatacta ttggatttat aatatttaac aaagcatatg gaccatatgt tagtgcagat
    29041 acacctaatg ttgctgttat ataagccccg catgtattcc atggtactaa tggagaagtt
    29101 aaagttccac tatcttctaa agctctcgac aacatcttag gatgtatacc tctcttttta
    29161 tattccttat tatacattct tcctggtata actatagata gatattgttc acctgctatt
    29221 atattggtaa ttgtacaagt taccatcgta cataatactg ttccaaatac acccttagct
    29281 aattttagta aagaagatgc tactacttca agcatacctg ttttttctaa aatacctcca
    29341 agagataaag cacatattgt taaagacaca gtggacatca tattcataat tccgccttta
    29401 gataataaag catctacctc ttgtatttgt gttgacgaaa catatccatt ttgtgctgca
    29461 tctaatatcg tattcataga ttctccttga aaaactactg caaacaatac tcccaataca
    29521 gcacctacta taagccctgg tatagcagga actttaaata caactaatcc aattactatt
    29581 gccggagcta ataataatac tggtgataaa gtattaaatg tagaatctaa tgtagaccta
    29641 attaactcta tctgttttat atctagcgct tgacctgaat acttcattcc gattacacca
    29701 taaattacta aacaaattaa taatgatggt atagtcgaat atagcatata ttttatatgt
    29761 gtaaataaat ctgttcctgc cattgctgga gctaaattag tcgtttcaga taaaggtgat
    29821 agtttatctc caaagtaagc tccagatatt atagaaccta ctattagtcc aactggcata
    29881 cctaaacttt gaccaattcc taaaagagct actcctactg tacccattgt actccaagat
    29941 gaacctgtcg caagagatac tattgcacag actagtgttg atgctactaa aaaaacattt
    30001 ggtgataaaa tttttagtcc ccagtaaatc atacatggaa ctactccact tactatccaa
    30061 gttcctataa gtacgcctat tataattatg attaagattg cctgcattgc catctttata
    30121 ctattaaaca tacttaattc taactctttc catttaaatc caagtctata tacagccaca
    30181 agtcctgcca ctgctgcagc tcctattagt ggtacatgag gtgatgaacc atatactaat
    30241 actcctagac ttaaaaataa tatcaaacaa gtaattggta tcattgcatc aaacagactt
    30301 gcttttctac attctcgctc tttcataaaa taatttcctc ctaattattt aaacactaca
    30361 ctataatttt ttttgaaaca tatttactcg tactagatga catgatacca ccataagtta
    30421 ataaaaattc tacactgtca cctaatttat aatcatattt tgtgttgctt acatctagta
    30481 tcatgtggtc tgagcttgcc cctaatattt ttatatcagt gtctattgga attaaagagt
    30541 caatatttat atcctgttta ccgatggcta taattgccct ttttaagatt cctttatctt
    30601 cataaacagg cttatttcta aaagcatcaa atcctatttc tccaatagga actgatggct
    30661 tttctttaca ttcaactact tggcatatta atttaaatgc atcttgatac gttccattta
    30721 tattttcacc gtatgccgtt tctctaccaa gtagaataga ttcgcctatt ctcagattag
    30781 taattccttc tggcatatta tcatttgtca tcagatgtat agaacttgaa ttgcctccag
    30841 atactatttc tagatttatt ccaaatttgc cttccatttt ttgtgctata cttgctagtc
    30901 tacctatatt ttctctagag ggtataatag ctccataaca agttaaattt gtagctatac
    30961 caattatttt aatatttttt aattttatta tctctctcac attataaaaa aaatcttctt
    31021 cataaaaata cccttctcgt aaatctccta agtcaaacat aaggactatc ttatgaataa
    31081 tatttttact ttcacataat tcatttaatt tctttattgt tcctaactct gagttaaaac
    31141 taatatcaca ataattgata acttcttcta attcacttaa cattgggatt ctaatcaata
    31201 tcttaggtaa atttatgtct tgtaaatttt ttaagttttg tattcttgaa tctgctatat
    31261 ggtctattcc ttcactacat attgctttta ctacttcttt ttgtgcacaa aatgatttag
    31321 tgacaaaaga tatcttaata tttctttcgt gacacatctg cgaaattaat tttgcattat
    31381 gctttaactt ttctatatct atttctaacc taggatacat aatctttcct cctcaaaatt
    31441 caaacttttt aataggagct taagagatgc ttcttcatat tttttagata aaacacccat
    31501 agatgccata atataatcat tatctatcaa tatctttgtt ttttcctttg gaaatagtaa
    31561 ttcattattt ttattgtatt taagcatatt atctaatatt tcaattctac tagggagcct
    31621 agtaagtgct ccccctgtac caactatata tcttacttct gttaaatctt tcccttctgc
    31681 aattttgatt ttcccagttg ttccatagat atttcttatt tttcctgaat gtcttaacat
    31741 agctttaaca acagcttctt ttgttaatct ctcaacaaat aatatttctt cttttgactt
    31801 tggtattgga ggataattct ctattactgc atcaatatct atagataatt cactttgtaa
    31861 gttttcttta cctatcactt ccactatatt cttcatattt acatatacac ctaaatcacc
    31921 ctcaacactc ctctttgcag taggttcagg attaactaaa attttattaa tatagtcact
    31981 tccatctgta acagaatgta catcagtagt tgctccacct acatccagag ttaataaatc
    32041 tccaatattt ttatataaga gtttagaagc ttccattaca gctcctgggg ttggagtaat
    32101 attttcatta accatttctt taatgtattt cattcctggt gctgtagtta tgtgttcttc
    32161 aaatacactt tgaatgattc ttcttgtagg ttctatattc aataaatcta ttttagggta
    32221 tacattttca gttatataaa gcttataatt agtatcttca aatattaacc ttacttcctc
    32281 ttgattttca atattcccag catatataac tggtatgcct agattcatag aagctatcat
    32341 ttctgcatta taaatagctg tatctctttc tccataatcg actccaccag ctattaaaat
    32401 tatgtttggg tttatttctt ttattttatt taaatcagtt cttttaattc tacctgatgt
    32461 tacttgacga ataacagctc cagcccctag ggcagcttct ttagctgctt ttactgtcat
    32521 atcatagact aatccatgaa cagtcatttt taatccacca gctgcactag aagttgcaaa
    32581 catatcatta tactctatat tatctacaga taatttatta gctaaatcct taatagcacc
    32641 tgataaaccg tttcttacat cgccaccttc aaacactgtt gttggagctt gaccttgacc
    32701 caaaaataca ggattgttag tatcaatatt atggaaagcg tttaccacag tagtagtgct
    32761 tccaatttca gctaccaaca catctatttt taaggaaact ttgctatttt ccattattta
    32821 ttattcattt ctcttctttt ttcaactaag aaagtggcta catgtatgcc cttgctgttt
    32881 cttccaaatc cagcatctat tccttgttca acggctattt caggtgttac ttgtgtccct
    32941 ccacacgcaa tcattacttt atctcttata cctttttcca cacaataatc gtgtaatttc
    33001 ttcatgtttt tataatgaat atcatcatga cttattattg tagatgcaag tattgcatct
    33061 gcattcagtt caattgctgc atctaccaat ttttctacag gtacagaagt ccctagatag
    33121 tggcattcta taccatattt ttcaatacca ccatgtttta tatctattat ttctcttaaa
    33181 ccaactgaat gttcatcttc tccaaccgta gctgaaacta ttttcatagg tttttcttct
    33241 atatctgctc ttatctcttc atcagttaat accttaggtt cttctggtat tactaaattt
    33301 tttaaatcta tatcaaatgg aactcttcct ttcacttcta tcctagtccc ttcagattca
    33361 tgcataacct ctctacttat aacctcagtt tcttgtaagt tcattttttt gacaaactcc
    33421 agagctgcaa attcagctgt tcttttatcc gtaggaagca tcattgttat cattacaatt
    33481 ccatctgcac accattccat ttcaggctta atcttagttc catttctata ttcatctgat
    33541 tcttttaatc tattctctac attatcaaaa tcgtcaagct catcaatata tattatttta
    33601 tctggatttt caaatgtaca tccatctatt aatattgatg gattatctat agcattttta
    33661 tcgtattggg ctacattatt gtatccaaag tgagcagtta caggtgctaa ataatcttct
    33721 tctctttcat aaacagtacc ttcaccaact cctcctttta tttttctaga tattccatca
    33781 ccatttcttt ctggataatt tcctgagtca acaaagaatc cttgttctac agattcaaaa
    33841 tatccgccaa cttcaaatat ttcttccata tataatacag ctctttcttt aagttccctt
    33901 gctttttctc ttaattcacc gacatcttta agttctatca tatccataag accatccata
    33961 ccaactaaag cttgctttgc tgtatcacac gcttctatat tatatatatg ccaaggtaca
    34021 tttctacctt catcaggtgt tatagttgat tgtatgtcag ctctagttaa tactgatgtt
    34081 aataagttta atacatgagt aactgttgcc tctctagttg atgattccat atatttagta
    34141 ttcatttgag ctctcatctt ataatcacta aataactctc taagtgcaac agcataaggt
    34201 aagtctattc ttaaacatgg tgctggaggt gctgttggtg gaactgttga taagcatata
    34261 ttacttttat ctattcctat tttttctgag aatatagagt ttaaagcgtg ttgaaccata
    34321 agttcaggca ttaccttcca tgcttctcta gcagtagcat tagcattatg cgctccatct
    34381 atttgagcta tattagcaaa agccattatt tttttagctt cacaagcatc tacaaaagac
    34441 cttatcatat ttatatttct atatagaaca ttgtattgtg ggtcttggtg tgctccattg
    34501 actccttctt cagcaaacat tactgctact tcaggaccag caacaccact tacatacgaa
    34561 tgataattaa taggtctacc aacttcttct tctataaaat caagagcctt tctttgagct
    34621 cttacttgtt ttcttgttat tggaactcca cctatccctt ggggagttcc ttctataagc
    34681 ccatcaaaat gtgattgccc agcagttcta ataaccatta aatggtcagc tccatgatga
    34741 gctgccatcc tcattcttct tatatcatcc tcaaatctac cagaagctat ttcagtagta
    34801 ataactgggc ttggttgagg gtctatatta ttgaaatact tagatgatgg tagccccaca
    34861 ctgtctttta aaggttttgt acagtctcta tatttaaaag gtcccatttc aagattttcc
    34921 aaatgctctc tccaaaccca acctcttctt tttggtttat atttatccaa atcttttaat
    34981 atatagtcta tatccaattt tttattttcc tttaacatga ttctacccct tctctaaata
    35041 aacatgtaac ttcatcccaa tattcaccat taactaatag taaacctgct tctctaactg
    35101 ttatattctt agatttagcc aacttataaa ctacatgccc tgctccttta cctataagac
    35161 ctctttccat aaccccttcc agaataggtt ttacttcaag agaagaaaat cccattctta
    35221 acaagacaga cctttctatt gatggtgttg tattcttttt accaagttct atcattggtt
    35281 ctactatctg ggtagctaaa ctccaaaacc tttcttttaa ctcatcatca ctcagttctt
    35341 gaagatgttt tcttctaact tcaaaatcat cctctctttt tttcatgaac attcctccat
    35401 tcgtattgat ttaatcgaat tttccgaatt tttattttac attaaatcaa aaaacaacaa
    35461 ctactataaa ctatttaata catcaataac aaaatctctt gaacttttta cttcttccat
    35521 taaaaattct atatctcgat tacttagctt atcaatatta tcaatgtgat tattggatat
    35581 acaatttttt ataaatgact ttcttatctt attcatatca atatcaacac atttcaataa
    35641 ttctggtctt tctggtaata ttaagtttac tcctgcaatt tcttctcttg gatttccaaa
    35701 ttttatatct attccatttt ctcttgcaaa agtaagttgt ggacatatat gtttacctgc
    35761 acctgtatat tctgtttctt gtaccactat aactttatcc tcatctaact cttgagctaa
    35821 agagaatgct gctgctaaag atgtatttcc tgctggacct ctttctatac cttctagctg
    35881 tgccaataat tcagttgtat aaaaaacttc tccttgtttt actaacacat atctatccat
    35941 atatctaagt ggtctagctg cagacctagg tacatctgac ctatcaggcc atgtacagta
    36001 tggtatacca aaacctgtat gtcctgttgt aaatgatttt ttattaaatt gattatcgct
    36061 agccatgtgt aaccctttta aatctacact tgctcctact actttagtat taatagaacc
    36121 agcttttatc aatcctcttg cagttccagt aagattacca ccacctgcat ttgtacaaac
    36181 aactatatca gggtcttttt tatacttttc tctaaattgt atagctaact cataacctaa
    36241 agtttctaca cctgcaattc caaatggtga atataatgat gcgttaaaat agcctgtttc
    36301 ttctaataaa actaagaacg tataaaataa ctctggtcca acagttaact gaacaacttc
    36361 tgctccatat gcttcacatt ttcttgcttt ttctataatt tcaggctgac ctacaccatt
    36421 agaatcataa cactcttgaa ctattataca ttttaatcct tgcattgcag cttgggatgc
    36481 tacagctgca ccatagttac cactagtagc tgctattaca cctttatatc ccattttttt
    36541 agcatgatat actgcagtag ctgctcttct tgctttaaaa ctaccagatg cattcattgc
    36601 ttcatctttt acaaatattc tagctccttt accttcttta gcacattttc tagctaattt
    36661 agtcaaattt ttaagctcta ttataggagt atttccaaca gcatattgtg attgaattac
    36721 ctcaatatct tgtaatgtat atcctgtttc actcatcatc ttctcataat caaaccctat
    36781 tccttcttgt tcaaaagaag agtaatccaa tccaattgca tttttcatta tttcgttatt
    36841 tcttcccata acagcttgat aactcatatc tttcattgat gctgaattat tcattagata
    36901 cacctccaaa taatatttct ttagcttgga ttcctatttg gagtaactct ggtatacatt
    36961 taccataatc atgagtataa tatgggttta ctttaagtaa attacctttt acaagtctac
    37021 ctgtaattgt tttaacttct actaagtcgc ctatagaagc atcactttgt ataaaacctt
    37081 taacccacat ttctaaggat actttcttag tatcctctgg aacttgtgga gctctttctt
    37141 ctggagtcaa tactatattg tgtataataa cccaatcatt aattttagca tccatttttt
    37201 catcccctta ttaattgact attgtcttac taattaattt actgttattt taaattaact
    37261 attattttac caattagtta gctgttatct tactaattag ccttcgattc ttcttccaat
    37321 tcaacttcta tctgatttct tatatctccc attattgctc taggtactgg tatatccaac
    37381 atagttttaa gacctggtct agcatttatt attaatggaa tagagtttac tatcattgca
    37441 taagtaccta ctcctccagg tatttcagga tttatttgta aatcaatgtt tggtatacct
    37501 tttattgata cataatcgcc tgttttaatg ccttccgctt ctggtattat ctgttgtgga
    37561 tgctccattt caattaaaac ttctccattt acatatccat atccacattg tctacaacca
    37621 gcaacatttc cagccaatgc ctctccgtac ttagattttc tatctactgt agtcattatt
    37681 ggttcttttg tttgttctat cttatctagt ctccatccta atccatccgc tatcatattt
    37741 attgattcta caaaacctac atgacccgct atagtcttat cttctacacc ttttataaat
    37801 tcttctcttg ttgctccaac accttgttct accataacag actttccaaa tggagataaa
    37861 tcatttactc tcttagcttt tatactagta acttcttcac aagtacctga aagtgctaat
    37921 actagtaaat ctaatacaaa ccctggattt attcctgttc caagtatact tactccattt
    37981 tcctttgcaa cttcatccat ttttttagct aaatccacat catcagcttg tggatatgcc
    38041 atttgttctg ctgttgatat aacatttatt tttctattta ataagaatag tattttatca
    38101 aaagcctttt tagtaaatga atcagttgcc aataaaacaa catctacgct tttttctcta
    38161 aaaacttctt cataattttt attgataata acttctggtc tttctcctct ttcaattcct
    38221 aagacatcat acatactttt ccctgaagta cttctactac aaacagatac tatttctata
    38281 ccttcttttt ttagaatcat attagccata cctattccca tagctccaaa tccccatatt
    38341 cctactctta cttttctcat atatacaccc tcctaaaaat ttatatattc tcaataatta
    38401 gttaaagcat aaatcgtgcc aactttaaaa ttaaaataaa tatttattag agtgttgaaa
    38461 ctataattac tttattacgt attttcataa ttaaaaaata atatttcttc tgaaaaataa
    38521 aaaaaagagc aaaatatttt gctcttttat aataattttg ctcctttatt ttgctttttt
    38581 actttacttt gattgttcct ctattttgct cttttttatt tataatattt tgatattata
    38641 tttttttatt ttatactgta aattttgcct attcatacct aaaattgatg cagctttagt
    38701 tatattgtat gatgtctttt ctagcgattc atatatatat ttttcttcta tctcactaat
    38761 aatcttacta agtgttttgt cctccaaatc atttaaagaa taatttttac tctctttatt
    38821 ctctttaaga ttgtaatagt catttaaatt aatcatactc gtttctattt gtacctcgtc
    38881 ttccatcata ctcatagtac aataaattat gttttctagc tctcttatgt taccttgcca
    38941 atcgtaattt tttaaaattt taatagcttc atctgaaatg cctattactc ttttatttaa
    39001 ctttttatta tattttgaaa taaatttttt gcacaataga ggtatgtcct cttttctatc
    39061 tctaagagga ggaattttta tatgaattat gttaagccta taatataaat cttttctcat
    39121 tttatgctca tttaaaatga cctttggact ttcatttgtc gttgcaataa ttcttacatc
    39181 tataggtata tccttagttc ctccaactct tcttacataa ccttcttgta aaacccttag
    39241 taatttagcc tgtaacataa tgggcataga atttatttca tctaataaca aagttccttt
    39301 gttagcttgc tcaaataagc ctggcctatc tattgcccct gtaaatcctc ccttgctagt
    39361 cccaaaaagt ataccttcga atagtgattc tggtaaagct gcacaatttt gtgctataaa
    39421 tggatagttt ctcctattac ttccatagtg aattgactgg ctaaataact ctttgcctgt
    39481 tccagtttca ccatatataa atactgaagc atcagacttg caagctttct tagatttttc
    39541 tattgcttct ttaatcaaat tactttcccc taaaatatca tcaaattcat agcccttttt
    39601 ttgtctacta ctaaccttat tgactaaatt ttttttatag tttctattta gtaaattttc
    39661 tatagttgtc atattttttg atatttcaag tgcccctaca aactctcctt taatatcaat
    39721 tggtattgta gtattaattg ctgttatttc ttttccattt ttatctagat atttttgaat
    39781 attgtctttg ataatttccc ttttttccaa aacctctaat agtgtacttc tgtttatttt
    39841 cattttgttt actatatcaa aaaatgaatt ggttaaaata tcatgtctat tcattttttc
    39901 cattttttgt acagaattat tgtagattat agttttcccg tctttattaa caaaatgtac
    39961 cccttcatca atattttcca atatttcatt cattatttta aaaaatatct cttggttcaa
    40021 ctatatcacc ccagtaccta aatatataaa aacccaaaaa attaataaaa tatttccatt
    40081 gtatttatct tatcatatat ttatgatatt ttttatgtac attatattaa tatattttta
    40141 agtatattta aaattttatt tatatatctt tcattatggt tatacaatag ttgaattgtc
    40201 attaaatttg ccaatagttt
//
LOCUS       DAMKOJ010000033        39224 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000033 DAMKOJ010000000
VERSION     DAMKOJ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.035"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            270..1046
                     /locus_tag="PC592_001828"
     CDS             270..1046
                     /locus_tag="PC592_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF4055803.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADAINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPE
                     GLKGFTEKSITDFDVLYDQLLEIQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            1378..2523
                     /locus_tag="PC592_001829"
     CDS             1378..2523
                     /locus_tag="PC592_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF4055804.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKNSIKSLGTKKAFVVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYNEVKQNPTVTNVNKGLEILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIVAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDNNSLSTITVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSSPSKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENAMKDACAGANPVFFDKKKIIELFMKIS"
     gene            complement(2704..3573)
                     /locus_tag="PC592_001830"
     CDS             complement(2704..3573)
                     /locus_tag="PC592_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF4055805.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDNKTGYVFNYFLSTDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPDTPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(3689..4402)
                     /locus_tag="PC592_001831"
     CDS             complement(3689..4402)
                     /locus_tag="PC592_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015359980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HDF4055806.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELIRLIKAKEEIEWLLNRDYKIDP
                     IVNFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKENTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIINKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKDCNIVNLNK"
     gene            complement(4771..6159)
                     /locus_tag="PC592_001832"
     CDS             complement(4771..6159)
                     /locus_tag="PC592_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF4055807.1"
                     /translation="MKKIFDAIIIGFGKGGKTLAGNLANRGLKVALIEKSNKMYGGTC
                     INVACIPTKSLENSANNVKTKNINSWDEVQVEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENKIYELVADNIFINTGSRPFIPNIKGIENKNVVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGTEVTILNSNNGILPNEDVEDSEEI
                     IKLLEKRNVKIINNANIKEIKEVSKLAIVEYEVDGKSKELASNIILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIIINQLFGD
                     KTRTTSDRKNIPNSIFISPAFSRVGLNVKQAKEKGYKVLVANMPIEAIPRAKQIGKTD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPSMIKEV"
     gene            complement(6280..7557)
                     /locus_tag="PC592_001833"
     CDS             complement(6280..7557)
                     /locus_tag="PC592_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HDF4055808.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMRAITAFLLGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNMSQNSKIESKQEENKRENSTNKEERSEGNDSQKDSNNENNDEG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPHIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            complement(7694..8029)
                     /locus_tag="PC592_001834"
     CDS             complement(7694..8029)
                     /locus_tag="PC592_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055809.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQRDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNIVESTYFLSESGLLLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            complement(8480..11080)
                     /locus_tag="PC592_001835"
     CDS             complement(8480..11080)
                     /locus_tag="PC592_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDF4055810.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLYKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSSKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKVKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARMH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLLNTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISERLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDAIIIEETYVKPRENVLEETPAGNVFIEEPGYYILKVR
                     INIQLPALGYKVVSFESSDKEMVSLNKSNDSFISNDSYKVIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDRAYTEKALGYEKLVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVIIILSKENPLMDVKLCINNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIKDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQIFKKLEFSFAIYMDSKS
                     FDELEIANFTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIINKTVSRELEIISLPENY
                     LISACYPSYYSKDKFVIRLENQSSKRMILDEQIFKNINGKIVNAIEDVEEEQLYEIAP
                     FDVISILLDL"
     gene            complement(11110..12225)
                     /locus_tag="PC592_001836"
     CDS             complement(11110..12225)
                     /locus_tag="PC592_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF4055811.1"
                     /translation="MEGNVMLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGS
                     FYNIPDIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPG
                     LVGGMIAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLIT
                     VVLINYVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTS
                     LALLTSGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSE
                     GAIPFAVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSI
                     VVGTVIVAGLVIVLRGNPVIEDDEFEDDDFDESEWEA"
     gene            complement(12226..12546)
                     /locus_tag="PC592_001837"
     CDS             complement(12226..12546)
                     /locus_tag="PC592_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF4055812.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            complement(12549..13010)
                     /locus_tag="PC592_001838"
     CDS             complement(12549..13010)
                     /locus_tag="PC592_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4055813.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHRIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            complement(13010..14974)
                     /locus_tag="PC592_001839"
     CDS             complement(13010..14974)
                     /locus_tag="PC592_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4055814.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIASDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLVRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIEILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKEEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVAADQHRDTNELKNTSTNPCETNTNNVSNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDNECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSGCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKCFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            15140..15994
                     /locus_tag="PC592_001840"
     CDS             15140..15994
                     /locus_tag="PC592_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar uptake protein"
                     /protein_id="HDF4055815.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMVSGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVSRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKENKNKKEWFSILIGIMLIMSG
                     VFMLSIIK"
     gene            complement(16236..16703)
                     /locus_tag="PC592_001841"
     CDS             complement(16236..16703)
                     /locus_tag="PC592_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HDF4055816.1"
                     /translation="MKTKEEYLKEVRTTAEECFRRGEFFCSEAVLHTINNALGQPLSP
                     EITKLASGFPVGLGKAQCLCGAISGGEMALGLVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRVITKKWDGDNFMSPERKEHCIKITGQVAEWVADKLIEDEKLNIK"
     gene            complement(16807..17739)
                     /locus_tag="PC592_001842"
     CDS             complement(16807..17739)
                     /locus_tag="PC592_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDF4055817.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGVIGFILY
                     AIYIIKIVLLRKGVKEQLENPLISSTFPTITMATMIFATYVKPLSLELGIMIWSIGVV
                     GHLVLIVLFSKKFLIKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLINGHLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIHLSKSETTSKAK"
     gene            complement(17908..18852)
                     /locus_tag="PC592_001843"
     CDS             complement(17908..18852)
                     /locus_tag="PC592_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HDF4055818.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMICDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELARKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRGDAKISIRDMKTIKVDKNKQISIFD"
     gene            complement(19492..20166)
                     /locus_tag="PC592_001844"
     CDS             complement(19492..20166)
                     /locus_tag="PC592_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF4055819.1"
                     /translation="MNDELKTILYSKGVDIVRFVDISEFPTSQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTGSDEFLEKEEKVEGLADWISKYIQSKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RHPLIDSKCLDCNICVENCPAKAIHGNEWTLPGERESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            complement(20226..20972)
                     /locus_tag="PC592_001845"
     CDS             complement(20226..20972)
                     /locus_tag="PC592_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDF4055820.1"
                     /translation="MKIENLSINDIKRGYIFNDDLNCYSCIKCTKIYEIGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQMINSDSKYNTLTENQKQLFQLFISDLPDKEIAKKVG
                     VSTSTIRHQKFMFREKAKQAKLYLALYESVFEDKSNKGSTIISIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKQYSEKEVNQILES
                     IYGDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            complement(21450..22136)
                     /locus_tag="PC592_001846"
     CDS             complement(21450..22136)
                     /locus_tag="PC592_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055821.1"
                     /translation="MAILELINVNYKYEGSSKFVLKDVNAEFEIGKMYVIVGKNRAGK
                     STLLSVISGLDDCTSGSIIYKGEDLKNINKNIYRSKYIGSIFKNHNLLNDATVLDNIV
                     LTMLIAGNKAKNKEDIVYDILKKVGIDKEKANCKVKDLSQDDIRRVCIARALSNNPEL
                     IICDDIIENTDDKGEKSLVDIFYKLASEDNKCVIITTTFDRIALYADELWGITNGNLM
                     FVKSLEKLKY"
     gene            complement(22147..23505)
                     /locus_tag="PC592_001847"
     CDS             complement(22147..23505)
                     /locus_tag="PC592_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055822.1"
                     /translation="MYILNNAIKNLIRNKVHSLFSIVIILLMVLSIAISSIINLNMSI
                     ITQKYEKKLESEVSIKIDEKKVVQNDLTESLIGYDPLNLEDYLNFSKSKYVKKMSLTG
                     NLALYVDNKKYAPSNDKKLDYNDITTNCIVMGFTDKNKSLKYYNLNISKGRVFQKDNE
                     CIVSEDFLKAGNFKVGDTISLLNDYNTNVKLNLNIVGVYKTKDSNKLESVQDVSIYNN
                     ILTSYNTLVTFEKRVRPESKMIYTSASFLLRDSNSRKAFEKELRNKGLSDIYKVTIDE
                     LLYHKLMAPIERLSGVVFTYTLGILVLGSILLVISSAISIKKIKYDICVLRLIGMSKF
                     KIIRSFIYESIMIILISTVLGLGIASISEKSISNYVFEYQYKYNITYNDFLFNKGSYK
                     DVNTNDINTEQEMKNLKDKSTLNFILKIIFISMILILLTSTVSIYNAIMCKPIQIIYD
                     RN"
     gene            complement(23567..24613)
                     /locus_tag="PC592_001848"
     CDS             complement(23567..24613)
                     /locus_tag="PC592_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055823.1"
                     /translation="MQGLKDKKTIALILYSVIVFIIFTVGLKYIINISDIDKNLISRD
                     TTLSKSEIPLNNSYVLDKGLMTNYNLILKNNFNVVIILFFAFIVTSNFILLLILNRLD
                     FKERIEILNNINNIEDENEILSIDPIMSRVYKDLKNKFDSHIEDYKRLNSYLSHEQKN
                     AISILRTSLELDGNKELLNVLDKVSNSVEDVLAISYIKNNEDMYEVDIALICAQVCDN
                     YSKVYSNLKFDFDEDENMSIFGREKWIYRGVSNLLDNAIKYGEGKEIYINVKNQKGSV
                     IVSVKDNGIGMNQHHIDKIFYDRYRINELNKDGYGIGLSLVKHVCNLCNGFIWVESEE
                     NKGSTFYLVFKEYK"
     gene            complement(24601..25272)
                     /locus_tag="PC592_001849"
     CDS             complement(24601..25272)
                     /locus_tag="PC592_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055824.1"
                     /translation="MRVLIIEDNKELSYNIKSGLENAGFVVDIANCGLDGEEKAFVND
                     YDAILLDLNLPDKDGIEILEFFRSNNLNTPVIIVTARDGVNELAKGLDLGADDYIVKP
                     FQIIELRARIQAVIRRFYGRTNPNIESGPITINPSSRKVYVYNEEVTLGTKEFDIVEY
                     LASRYPDIVSGIDISEHVYDEYFDPLSSVLRVHIARLKKKLREVAGKEIIITTRGIGY
                     SICKD"
     gene            complement(25659..26543)
                     /locus_tag="PC592_001850"
     CDS             complement(25659..26543)
                     /locus_tag="PC592_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF4055825.1"
                     /translation="MRYDIAIIGSGPAGLAAAINAKIRNKNIILFGTEDISQKLIKAP
                     SVENYLGISNISGLELKEKFKNHIDDMGIKITQNRINNVYSMGEYFTLVSGNHVYEAT
                     TVVLATGIEYGKMIKGEDAYLGKGVGYCATCDAMLYRNKKVAIIGYNYEAEEEANFLS
                     EIASNVYYIPMYKLENKINSGINVIDDKPLEIKGGKLVNKLVLRKSELDIDGVFIIKD
                     SISPKYMVPGLEVEGSHIKSDKNMNTNIEGLYVAGDCAGKPYQYLKSAGQGQTAVSSA
                     ISYLDKQKIKEFMLVDAH"
     gene            complement(26709..27026)
                     /gene="trxA"
                     /locus_tag="PC592_001851"
     CDS             complement(26709..27026)
                     /gene="trxA"
                     /locus_tag="PC592_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF4055826.1"
                     /translation="MIKIINHNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     DEMAEKAKFLKVDIDQSIELAQKFEVSTVPTMMIFKDGKPVDRLIGFMPKDNLKNKVE
                     SYM"
     gene            27278..28030
                     /locus_tag="PC592_001852"
     CDS             27278..28030
                     /locus_tag="PC592_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDF4055827.1"
                     /translation="MNDIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYVPISPNELLKNKKEEFNNSMDKLKNNLQILNKG
                     KNIEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKNLEGLDNIHIHGGNKTTLENKMLYKGIILIVDNNEILTGNLSEGNEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQD"
     gene            28017..28898
                     /locus_tag="PC592_001853"
     CDS             28017..28898
                     /locus_tag="PC592_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF4055828.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTNASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLDSNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNYRKELAQMIGVHEDRLLEYPIMKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVNQNILDKTSFIGEEGNFINRPGKVYVNIAKENNEITS
                     VKIGGSAYTVLSGEIIY"
     gene            complement(29125..30480)
                     /locus_tag="PC592_001854"
     CDS             complement(29125..30480)
                     /locus_tag="PC592_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF4055829.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYSAKFLIYIFLTTAV
                     IHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDNQEELDTAFSVQYSFVNIGSFI
                     GTTAVGILYAKTFAKNGVLGFSQCFFIAAVLCVIGAIWFTYGWRFLGNAGKRPFKEGV
                     VAEKVEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVDMTIG
                     GFDIPLAWFDSLNALVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFTRGVGAPETAKASIMWIIMFGILLSFGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGQGYGYIYAFTLKFEMIKVYTIIPVILFVAAILLFLFDKTLNRLVEDD
                     K"
     gene            complement(32342..32851)
                     /locus_tag="PC592_001855"
     CDS             complement(32342..32851)
                     /locus_tag="PC592_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF4055830.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLNPI
                     YSNNTIIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(33062..34471)
                     /locus_tag="PC592_001856"
     CDS             complement(33062..34471)
                     /locus_tag="PC592_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055831.1"
                     /translation="MENYFDKQAKELYDKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMLREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKSELPWNLYL
                     NRMMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDISGSISDEEFKQAI
                     KEVLSIVKNYNHEIIIIECDNEIRRVYKVKTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVETNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(34475..35605)
                     /locus_tag="PC592_001857"
     CDS             complement(34475..35605)
                     /locus_tag="PC592_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4055832.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LVAIDGNLLKEGEIGGLPTIESYVGVNSSGYKTEKKTTVYAVHNKLREIDEEISKGKI
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKENNNSIPRAVFLNVIKGNVGKVIAEEFISFIESDSKPLISYEEV
                     FLGESIDESIVERVKKESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIKFLKMY
                     PVDLMIGIMKDIRNSYTEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(35617..36420)
                     /locus_tag="PC592_001858"
     CDS             complement(35617..36420)
                     /locus_tag="PC592_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055833.1"
                     /translation="MEKSRVIEMIKNNPNIISTIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEEMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYVKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYSAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYIVKKISKDELEEVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRHSENIPIDKIMFIYKYGSKTAKKIAVDEKLKIV"
     gene            complement(36834..39041)
                     /locus_tag="PC592_001859"
     CDS             complement(36834..39041)
                     /locus_tag="PC592_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HDF4055834.1"
                     /translation="MYSKIGGINLKKIKKKRIALLLATITTLTFNQKFLVHAYENNYN
                     SEEKLWLPDFTDNDRAKQLEISKLTEKVNLNSIALERIKNINSKQIIENVSPAKLGDE
                     IVKQGDTSNFSLEDNSENIKLPSNVDNSQTKYFPNIGSQGSLASCASYATAYYTMTYM
                     TALVNDWSVKDVSGKNIDSKIFSPKWSYNFINDGKDAGAFAYQNYNVFKTHGCATLAD
                     FPYVGLGRDPKNYREWAKDENIWRNATKYQVDEILRVNFNKNNKPNSFITSNKDSNLD
                     DAKRLLLNGYILNFYTWFSDANYKQISNDPSTKDDDSYVNQKAIYQINNQGAHEMTIV
                     GYNDNIWIDINSNGKVDDGEKGAFKIANSHGPDYANNGFVWMAYDALNKKSSVLDFTN
                     SNARQGAFLNNEAEYVVISKKETPSKLVRFTMQHDNRKQLQVSLVYEKNGNKQTVVYS
                     PLLSYSGGDFPLDGVNNGSEITFVIDLAHLEKELNVSLSSADKIYLQIKDNLKDDKVA
                     IIKSIILVDNKGHKLSPELISKNVEINGDSKMFDLGQIDNSSELYLQSPEISTDKTLS
                     NNGKFNINVSVPPNNSATKLELFENNVPIETKDLVRSSELQNINFDMSDKKEGFYTYF
                     AVLEDGNGKCLKSEEVNIIVDSIIPPSIKISPNPNKVDVEVIVPAMNNAKTLNVYMDG
                     QKIVNEELSVRNPNEVKKSFVLYSLIVGTHTFWAEVEDENATISSQKVSITID"
BASE COUNT        13270 a         6431 c         4024 g        15499 t
ORIGIN      
        1 cataatattt tgatatttat atataaaaat aactattaca tatatttact taaattatat
       61 aactaaatat cacttgcttt ctttaggtat attttggaaa ttagttactc cttcctatac
      121 aacctaaaaa aatatctata ttcatctaaa ttaagagctt atttatatat aaatttacat
      181 atttattttc tacattgtaa aatatcgtat agtgtgctaa aatcaacata ttctaatact
      241 ttaaactaat aaaaagaggg gggaaattta tgacttcaga taatcatcgc ccaacagcta
      301 ggatattaga tattttagaa gcattagcag aatccgagaa tggatatact cttacagaaa
      361 tagccgatgc tatcaatgct ccaaaaagta gcatctttcc tatagttcat acacttaatg
      421 ctagaaaata tattactatt gataaaaaca catccaaata ttctataggg atacgttctt
      481 acacattagg gtcttcattt tttgaaaaaa gaactatttt taactatata attgatgaaa
      541 tgactaatat agttaattcc tgttctgaaa cttgtcaact tggtatactt gacaataatg
      601 aagttcttta tattggaaaa gtagattctc cagaaccaat tagacttatt tcttatgttg
      661 ggaaaaaaat acctgctaat tgtacaggtc ttggaaaggc tcttttatgt gattttgata
      721 aagaaaaact aataagctta tatccagaag gtctaaaagg ctttacagaa aaatcaatta
      781 cagatttcga tgttttatat gaccagcttc ttgaaattca aagaacacaa atagcttcag
      841 agtgcgagga atcaatggaa cacctaaaat gtcttgccgt accaataaga aaaaatggat
      901 gtataagagc tgctgttagt gtaacactgc ccttatttag agctaatgac gaaaaaatag
      961 aactaataaa aaaattactc ttaaatgctc agaaaaatat tcaatccatg atggaagaac
     1021 gtaatgaaga tattgtaata aattagatta atattctgta tacggaagat attaaaatat
     1081 aataattaaa aattttattt taaactaatg tatttatttg atttatacta taaaaacaaa
     1141 gttgctgatt taactacagt aactttgttt ttttataata ttttttatat tttcattgac
     1201 acgataaaaa tactatgtta aattctaatc ataatcgtaa ttacgaatct agttcttata
     1261 taagaaccac caaacctata tcaatctaac atacgatata ttatgggtaa attagtgaaa
     1321 attgttagat atatattttt acataaaaat caatgaaaat aaaaggagat tttagttatg
     1381 agcatttatt atgtaccacc aataaattta cttgggaaag gatgtcttaa tgaagctaaa
     1441 aattcaatta aatcattagg aactaaaaag gcatttgttg ttagtgataa atttctagtt
     1501 tcaaatggta ccgtaaaaaa agtaacagat attttatctc aaatagatgt ggattttgtt
     1561 gtttataatg aagttaaaca aaatccaact gtaactaacg tgaataaagg acttgaaata
     1621 ttaaaatcag aaaattgcga cttcgttatt actataggag gaggttctcc acaagactgt
     1681 ggtaaagcta tctctatatt agctactaat ggaggagata ttagagacta tgaaggtatc
     1741 aacaaaactt ctaaaaaatg tcttcctatc gtagccataa ctactactgc tggtacatct
     1801 gctgaagtta caataaacta cgttataact gatgaagata gacatgtaaa gatgataatg
     1861 gttgataaca actcactatc tacaatcaca gtaaatgacc cagaattaat gattagtaaa
     1921 ccatcaaatt taacagcagc aactggtatg gatgcactaa ctcatgctat agaagctgta
     1981 gtagctaatg gtgcttatga tgttacagat tcaactgcct tatatgctat aaagcagata
     2041 tttaaatatc ttccaagagc tgttaaaaat ggtaatgaca tagaagctag agaacaaatg
     2101 tgttatgctt gttttttaaa tggaattgcc tttagtaatg caggtcttgg aaacgtacat
     2161 gctatggctc atcaattagg aggtttatat gatttacctc atggagtatg taatgccatg
     2221 ctacttccaa tagttgagga ggaaaatgct aaatcatccc ctagcaaatt ccgcccaata
     2281 gctgaagtta ttggcatgga tgtaaataat aaatcagata aagagtgtgt tgactttgta
     2341 atagataaga taaaagctct ttctgaagag gttggaatcc caaaatcttt aaaagatgta
     2401 ggtgttgata atcctaattt tgaattgctt gcagaaaacg ctatgaaaga cgcttgtgct
     2461 ggtgctaatc ctgttttctt tgataaaaag aaaattatag aattgtttat gaaaatatct
     2521 taattataac aatctatccc ataaattaat tctgtatatt tataagagag tacctcaaga
     2581 tgtctttatt ttgttaatgg cactctctta ttacactttt taaatagtac tctttatgag
     2641 aagttaatat atagccttac ttatttaaaa ataattatct caataaaaaa cttaaatttt
     2701 ttcttaatgg attataacag ttgttgtatc tggtatatta tcatatatcc actttgcatt
     2761 ttccgtactt aatcttatac atccatgact aagagcttca ccaagtctgc catctattat
     2821 ataacttcct gttgaatcat atagtacaga atgatagtaa tatccacctt taattctagt
     2881 agcatactta actgaatact catccgttcc gaaagaaggt tttcttccac ttatataaaa
     2941 tatacctgtt atagttggag tgtcaggctt acctatagta cattgccact tataaagttg
     3001 tccccatcct ccattatctt tcttaaaaat ataagtatat ttatttctaa ggtctgttac
     3061 aattagataa tcgctagtac ttttaatatt attttcgtta acaaatttaa tcatatcagt
     3121 ataaaaatac ttataatcta attcatttgg tttatttcca tcagttgata aaaaataatt
     3181 aaaaacatat cctgttttat tatcatatac aaccttactc caatctccat ctacttgaag
     3241 gacttcaacc ctagattttt caggaattac tgtaattata ttggaagttg tagatttatc
     3301 ttctcttaag tttaagttac tccaagcata ttcgcttact gataccaaat ccttatacac
     3361 atatccttct tgagaattat acatcacctt aatccagtca tcttcttcat ccaatacttc
     3421 cattttagct ccctgaggta ttactgttat gatacttgaa ttagtagatt tagcagacct
     3481 caaatttaca tttgctaaag catatttata tataggtgct ctatattttt taatatttag
     3541 tttagttaat ttcacacata tccatcctct catatgtctt tttacaacat tttatgaaat
     3601 tcgatatgta ttcgttctcc tattttcaaa ctttacttgt attactaata atattgctat
     3661 atatacttat attctcattt ctatttatct acttatttaa atttacgata ttgcagtctt
     3721 taatatactc ttcaattata cctctagcca cattaaaata acttatacac ttatcaacta
     3781 taactgcatc actactaact actctatcta atttttccaa tacaacatct gcatttttta
     3841 ctaattctac ttcagtttca atcccccaag tttttgcatg ctctaatatc ctatacttta
     3901 aatttcctga attagaaact ggagcatcta aataaaattt aagattctgt gcattgtatt
     3961 tattaaaaaa tttacctatc agattcaaag cttcttctgt tttatttata atcttatagg
     4021 ttcccctaag acctgctaaa tctcttatat tgccatcact tcctattact agagtaccac
     4081 cagataatgc tacctctatg gatattatta aattaaagcc atctatattt acggtatttt
     4141 ctttgatttt atctaaagaa agcctctttg attgtcttat aatatttttt tcatcagtac
     4201 agactgccct ttttaatgca tctctttgtc ttatagaaaa ctggtatcta tcaccaacaa
     4261 aattaacgat tgggtctatt ttgtaatctc tatttaataa ccattctatt tcttctttag
     4321 cctttataag tcttattaat tctttacttg aaaaccatct tttatcacta tcatcaaacc
     4381 ctcttttaga aatcttattt atatcatttc accaccttac tttaaatatc taactatgct
     4441 atattaaata cagattattt caccttttag gataattttt aataccatta tcttatccat
     4501 ttaggttatt caatatttat aattaattat aacgcttaac tccacttaat aatacaaaat
     4561 aatagattct atattatatt tataacttta taacataaat aattagtgtt tcaaaataaa
     4621 tttttagttc ataacgtaat cttcttttat aaaaacaaat atatttttat catttaaaca
     4681 gtaaaaaaga gacttatctc tattttgaga tagtctcttt ctaaaatcta tttataatga
     4741 taattttaag ctttatatat taaacttata ttatacttct tttatcatac taggagatag
     4801 aatatcatta agagcttctg tcatagttgg atgtgcataa acacggtctc ttaagtatgt
     4861 atactctact tctaaatcca cagctaattg aatcaaatgg ataatctcac ttgaattttc
     4921 acatatcata ctagctccaa gtatcttatt ggatttttta tctatcacta tttttataaa
     4981 cccatccgtc ttgccaatct gtttagctct tggaattgct tcaattggca tatttgctac
     5041 taatacttta tatccttttt ccttagcttg tttaacatta agaccaactc ttgaaaatgc
     5101 tggacttata aatatagaat ttggtatatt ctttctatca ctagttgttc tagtcttatc
     5161 tccaaataac tgattaataa ttatgcgata atcatccaat gaaatataag taaattgtgg
     5221 acctccattt atatctccta tagcccatat atgctcttta ttagtcttaa gagtttctga
     5281 cactttaata aatcctcttt catttaattc tatacctgca ttttctagtc ctaacccttc
     5341 agtatttgcc tttcttcctg tagctacaag tattatatta cttgctaatt ctttagattt
     5401 accatctact tcatattcca ctatggctaa tttagaaact tctttaatct cttttatatt
     5461 tgcattattt ataattttta catttctctt ttcgagtaat tttattattt cttctgaatc
     5521 ctcaacatct tcatttggta aaatgccatt attagagttt aatattgtaa cttctgttcc
     5581 aaatgaacta taaatacctg cgaactctaa acctataaat ccagctccta taattgtcat
     5641 ttttttaggt aaagttctta gattcataag agactcacta tcatatacta cattcttatt
     5701 ttcaattccc ttaatattag gtataaatgg tcttgaacca gtattaataa atatattatc
     5761 tgctactaac tcataaattt tattttcagt tttaacttga actgtttttt catcaatgaa
     5821 agttcccatt cctgtgaata tagttacatt ctcatttgaa tttaatttat tatagttagc
     5881 ttctctaagt tttgtaatta aggtttcttt tttatctata gccttctcat attcaacttg
     5941 tacttcatcc caagaattta tattctttgt ttttacatta tttgctgaat tttctaagct
     6001 ttttgttggt atacatgcta catttataca tgttccacca tacatcttgt ttgacttttc
     6061 tattaaagct acttttaatc ctctatttgc taaatttcct gctaatgttt ttccaccttt
     6121 tccaaatcct attattatag catcaaatat ttttttcata taaatttcaa tcctttcttg
     6181 tattgtttat acttttacta taacaagatt acctaagtag tacaattagg cacttttttg
     6241 taaccttaaa ctgatttata aacttctact taaatacttt tatttatttc tctggttttc
     6301 aataaaggat gccatagttg ccttatccat agctcctgga atatactgag ttacatatcc
     6361 ttccttgtca attataaatg tagttggaaa agcattaatt ccatattgat atgctaatgc
     6421 tccatcttca tcaagcacaa cagggaaggt ataaccttgg tcttttaaga agttaactac
     6481 atgttccctt gaaccttctc tacctaaatt aggtgaagct actcctaaaa ttactacatc
     6541 atcattattt ttattatagt ctttatacag ctgttctata tgaggcattt cttctttaca
     6601 tggaggacac catgtagccc agaaatttaa gaatacaact ttgccttcat aatcacttaa
     6661 tttatgtgtt ttaccatact ggtctgttaa agtaaaatca atagacttta ttctatcttc
     6721 atcattagac ccttcatcat tattttcatt attagagtct ttttgactat cattaccctc
     6781 agaacgttct tctttattag tagaattttc tctcttattc tcttcttgct tactttcaat
     6841 tttgctattt tgtgacatat taaagtgttt gcttatactt ccaaatccat ttaccatcat
     6901 taatattcct gatactataa gtataatccc acctattttt ttaataattt ccatattaga
     6961 ttttatctta tctatagttt taaatagttt actgtaaaac atagctgtaa ttatgaatgg
     7021 caaaataaat ccaatggtat atactgctat taaaagattt gcactaagat gattacttga
     7081 acttgaaacc attactaata cagatgccaa tattggacca atacaaggtg tccatccaaa
     7141 actaaatgta aaacctaaca ggaaagctgt tattgctctc atctctttaa acttaacatt
     7201 aaatcttttt tctctattca atattgaaga tttaattatt cccatgtaaa ataatcccat
     7261 aataataatt ataatcccac caataaacat tattaaatct ttattttcat taaaaaacat
     7321 actcaatact tttactgatg aacccaatat aaaaaatgtt gtcgagattc caagagcaaa
     7381 aaatatagta tttttaaata aagaacttcc tataaaactc gtctttcctt ctttcaaatt
     7441 ctctacacta ctatttgaca atatgctcaa ataaataggc aaaattggca atatacatgg
     7501 tgaaaagaat gatactatcc cttctataaa cactaaaaat aaatttacat tttgcaaatt
     7561 aaaattcctc cttattttat ttccaatagt acaatctcat ttctaaatta aaatctgact
     7621 aaaaaattat gtaatttcaa tacatttttc tacttataat ttaattaact cttcactact
     7681 tccagagtaa attttagtat ttatcacaat ttaaattttt attgctccac ataatcattt
     7741 tttccatgac aggaagtaat agtaatcctg attcacttaa aaaatatgtt gattctacaa
     7801 tattattaac caactttttt tggttgacta taataccctg ttcaattaaa aaatctagtt
     7861 gttgaactaa cattttctta ctacagtctg gtatagctct ttgtaactct ccaaatcgtt
     7921 ttttatctct ttgtattttc catataatta tagccaccca ttttttacct aaaatatttg
     7981 ataaagcttc tactggacaa ttatatatca tatcatctat gttgtacatt ttattctcct
     8041 cttttcctta tttaatttat taaacaaact tttatagcaa tatatttatt aatattataa
     8101 atatacctag ctttatttaa ttaaaatttt tattatatat actcttatta caaactattt
     8161 tagattttat gtaattaata tatcagtttt ataaatacat aacaattggt aacttttttg
     8221 taactacatc aactctattg atatacaatt tctaactcat tttattaaaa ttttattgat
     8281 tttaaattat atataaaatc actctaatat aataattctt tatttaaatt gtttatcctg
     8341 ttaaactaat tattctactt ctataaattc tatattaaat aataaatcca tacattaaca
     8401 tttacccaaa tttatccaaa ttaaaaagtc tggcagatta atatctgtca gactttaaac
     8461 aataaactta cgtttacact tataaatcca ataatattga aataacatca aaaggtgcta
     8521 tttcatataa ttgttcttct tctacatctt ctattgcatt tacaattttc ccatttatgt
     8581 ttttaaatat ttgctcatct aatatcattc tcttactact ttggttttcc aatcttatta
     8641 caaatttatc tttactataa taggaaggat aacatgctga tataagatag ttttctggta
     8701 aagatattat ttctaattct ctacttacag ttttattgat gattgatttt tgaatcttat
     8761 tgtctatacg atataaaaag aaattataat cctgtaattg atagtttaca cattccctta
     8821 gataattgtg ggtaaaattc gcaatttcca attcatcaaa tgatttagaa tccatatata
     8881 ttgcaaatga aaattctaat ttcttaaata tttgagcttt atctgtttta attcttatat
     8941 gacctttttt agttgtatca ccagaagcac gtcctggtct atataataaa tcaggctttc
     9001 ctagttcatc tgtagtagca agcaaggtca atgcaatttc atctttaata tgttgatact
     9061 cttttattcc tctagtaaat acagtacaac ttctattttg gtttgtcagc gtaatattac
     9121 tttccaaagg ttctaaatct ataggcatct cactgtaaat atcttcccag ttgtctaaaa
     9181 ctccattttc tcttgttata tatccaaatg gcaatgatgc tatattttta ttatctttta
     9241 tatcagtttt tatatgaaca cgcaatctat gattatatat cgtgttatta atacaaagtt
     9301 ttacatccat caatggattt tctttggata atataataat tacttttaca tttaatttac
     9361 cattaagata tttgtttttt ctatcttcta atgtaagcgg tagtaaagta gtacctttaa
     9421 ctaccaactt ttcatatcct aaagcttttt ctgtatacgc tctatcaaat gaaagtttga
     9481 tatcctcatc attttttaat ggagaaaaat cataggtgtc acctgcatta ccactatctt
     9541 ttaatgttaa aaagtttgat atgtaagttc catctttaag ttgtaaattt aaacttccat
     9601 cttcatagat taccttataa ctatcattag atataaaaga atcattagat ttattaagtg
     9661 ataccatttc tttatcactt gattcaaagc taacaacttt ataaccaagt gcaggaagct
     9721 gtatatttat tcttactttt aatatataat atcctggttc ttcaataaat acattgccag
     9781 caggtgtttc ttctaataca ttttctcttg gttttacata agtttcttca attataatag
     9841 catctaaatt atctttaaaa taaatatttt tactatcact tacaacttgt atctctttat
     9901 atccattaaa gcgcttggct tctgtattaa atactaaaat gtcattttta gataatttaa
     9961 gcctttctga aatttttttg acaatagtat tttcaatact gtcacatatt tcatttgctt
    10021 ctcttatacg gtgaagaata tcatctgtta cagtatcagt tacacatcca gctaaactat
    10081 cgtgtgcttg cccttccaaa agttttttcc atgtatttaa aagtaactga ttgcttattt
    10141 caattttact ctttttagca attactagta atggttctat tcttttaatc agcttgtttt
    10201 ctagtttatc acatgctaat tttatatcca ttctactaga accaattgat ttatgcattc
    10261 ttgccaatac aggctctcta aattcacctc tatagctttc tagcgattct atggatttta
    10321 tatattttaa aaactcttga tatgaactcg ttatatatga atactttccg atatcattaa
    10381 tcgctttaac tttatttttg aaatcaccta ttatatttag ctggtcattt ccagaaggta
    10441 ttaacacctc atctacatca gtatatgatt taataaaatc aatagctggg tctaagcgtc
    10501 cattaacata ctttgatgaa ggttctaaaa gcataccagt tccatatcca tgtggcatat
    10561 ttactgcata tatataactt tctccattta agcttttcca cttaaaatat ggtgattgaa
    10621 cctgtttacc aagatgtata cctctccaaa agaatatatt atcaagacct acatgcttta
    10681 atagtatagg catctgtgca ttaaatccaa atgtatctgg caaatatcca attttcatat
    10741 acttaccata ctttttactt tcaaaaattc caatcattaa gtttcttaaa atagactctc
    10801 ctctagcaaa gaatgcatca gtttgagtaa accatggtcc aatatgtagt ctatcttctt
    10861 ttatcaactt tttaatgatt tctatttttt ctttgtataa ttgtacataa tcatccaaaa
    10921 tagaaagttg tccatcaagt acaaaactta catctgggtt acgttctaat tcatcaatta
    10981 catctgtaaa tagttgttca ctaagtacca atgcatctcc agaagtaaaa taccattctc
    11041 tatcccagtg tgtatgatta acaatatgtg cttttatcat ttattctcct ctgttcttta
    11101 tctttaattt taagcttccc actctgattc atcaaaatca tcatcttcaa attcatcatc
    11161 ttcaatcact ggatttccac gcaatactat aactaaccca gctacaatta ctgttccaac
    11221 tactattgat aacacataca ttggccaatt ctctactgta aaccatccat aaaatccact
    11281 aattggagtt gcatttactg aacctaaacc aactgccata gctgaagcaa ttgcagttcc
    11341 aattacgcat gaaggtatta cttttaatgg agattctacc gcaaaaggaa ttgcaccttc
    11401 acttactcca attaacccca ttataagaga tgacttccca gcttcacgta actgtttatt
    11461 atatttttgt tttgctagta tagtagcaag tcccaatcct agtggtggta taactattcc
    11521 taccattgca gcagtattag gtgcataaat tccacttgtt aataatgcaa gtgatgttgt
    11581 caaagctgct ttattaactg gtccacctag gtcaactgcc atcatagccc ctataatagc
    11641 cgccattaat atctgatttg taccagataa tccatttaac caattttcta atccagtatt
    11701 taatgtggca aaaggtatac ctatcacata gttaattaat acaacagtga ttaatgttcc
    11761 aaatactggt actataaata ttggtactat tgaagctgct gattttggta atttgacatg
    11821 atttttaata aataaacatg tatatcctgc tataagacca actgctaaag ctcctaaaaa
    11881 tcctgcacct atatctttag caatcatacc cccaacaaga cctggtacaa tagctaattt
    11941 atcagctata gaaaatccta taaatgcagc aattacagga aacattaatc ctaatgcagt
    12001 acctccaaat ccatctaaat catgcaataa tctaacaata ctactagcac tttctgcata
    12061 tttagcatcc catatatctg gtatattata gaaagaacca cctacacgag atattgccat
    12121 tatcatagca cctgcaatta ctagtggaat catatatgag attccagtta agacatgctt
    12181 ttttaactca gagactatct ttttcaacat tacatttccc tccatttatt tagtgtcaat
    12241 taactttaat gcatcattta ttactttctc tgcatccttt ataggcgcat taactggtac
    12301 ttctagtatt tcttttccct caaaacgttc agcatttctg actttagtgt ctactgcaaa
    12361 tattactact tctgcaattt gtgcatcctt tgtagttagc tcattatcga ttcctgtagc
    12421 tccttgtgtt tcaactttta taaggtgacc catctttttt gaagctttct ttaatgcttg
    12481 agctgccata tatgtatgtg caactcctgt tgcacatgct gtaactgcta taatttttct
    12541 tttcatctct acatctctcc ttcttcacta aatatattga ttatttcttg ttctgaattg
    12601 gctaatttta gtgcatctac attgtcatca tccataagtt tagttgccaa tttagataat
    12661 agtacaagat gattgctatc cttatcaata ttgcttatag ccaataagaa aatgctatct
    12721 actggttttt catctaaagc atcccactca attctatgct tagtctttgc aaatattata
    12781 gaagatttct tgacagcatt actttttcca tgaggaatag caataccatt accaatacct
    12841 gtagttgaat gctcctctct ttccaaaaca gacttaacat attcttcttc attgtccaca
    12901 atcccatttt caacaaatat actacttaat ttttttattg tttcttcctt tgtatttgta
    12961 tcaagattaa aaacaatttg ttcttttttc aatacatctg atattttcac tatatactct
    13021 cctccactag caaatcgtac acttcctttg tagaagttgc acttaatatg tcatttatat
    13081 tttttttatt gtcaatgaag tcataaaaaa cttcatatat ttcatcaagc tctaggtttt
    13141 tgtcattttc taacgaaata aagaaaataa cttctacctt ttcatttccc catgtaatag
    13201 gattttttaa cgttgcaaca gatatattag attttttaat ataactagga ttagcatgag
    13261 gtgtagctat tgattggaaa gatgtgtagg ataaattttc tctctcaatt gcacttttag
    13321 ctataccttc ttttgcaaaa cattttttta ttaggttatc tgttatatac ttaattgcat
    13381 cttcataatt tgaggcttca atatttaaca atatattttc ttcaaagatt aaatttctga
    13441 aagatttata cttcttagaa gtacaacctg aaacattttg tatatttctt tccaaggttc
    13501 ttatatcact ttcatttaaa atagggctaa ctactatcgt tggaatagtt tctagctcta
    13561 aataaatagt acttattact aagtctgcat caattttact agatactaat tcttgtacag
    13621 aaagcacttt ttcaatcttt atcattggaa agtatttttt tattcttgca gacaataacc
    13681 tagatgaacc tagccctgta ctacatacta gaattactct aatattttgt ggaagttctt
    13741 tcattctttc tctaaaagct tcaaaatgta atgctatata agcacattca ttatcattta
    13801 tcctaatatc atatataaat tcaattactt tctttaaatc taaagcttgc tcaaatgata
    13861 aagaaaagtt ttgtttgatt gtatttacat atggattttt aatactaagt ccatatttca
    13921 atctatttat tgatgaatgt acatgtgaag tcaatccatc aattaaatcc ttatcataag
    13981 ctgtctcata caatgtattt tttataattt cccgaagatt tgatacatta tttgtatttg
    14041 tttcacaagg attagttgaa gtatttttta attcattagt atctctatgt tggtcagctg
    14101 ctactaaatg taaatttata tatccaattt cagattttgg taataatatt gaaaattttt
    14161 cttctaattg ttttgctaaa taattggtat ttgacatttg attattttct atattaccaa
    14221 tatacaaact ttcttctata tattcttctt ttctaattct ctctacagct attgccaaat
    14281 gaataactaa cgactgaaat tcataatcag agaactcaaa ttttctttct ctgctgaaat
    14341 tcctaagaat ttcaataatt attgataaat catcttcaga aaaaatacca tttacatctg
    14401 cctgtatctt ctcaaatgct tgataaaagc tttcttgctc ttgcttaata taccagtttc
    14461 tactccaaaa tttatgtata aacttagcag taagttgtct tttatctctt tcacttatat
    14521 ttaactttat tcctttacta ggtttcttat atatggaaat cccttcattt tttaacaatt
    14581 tttcgacttc ggctaaatcc ctttcaatag ttccacgact tatatataat tcgtcagaaa
    14641 gttgttgtat agtgatatag tcattactct tcaaaagtac tgaatatata tagataactc
    14701 tctcctctct ggttgtagga atttgacttc ctttattatc taggtaagga agtatttttt
    14761 ttaaatctcc atcaatataa acacctatct taggttttct tactaaagaa agacctatct
    14821 ttttaagcac tgcttctact tctttaagag attttgaaac tgttttttct gaaacgtcta
    14881 aatcacttgc tattgctttt acagttgtat gaccttcttt taataaaaac tttattattt
    14941 taatttcacg attttgaatc atatcagtta acattttcaa ttttactcct tccctttgtc
    15001 tttattctaa tggaaaatgt ttttctaaaa aactactaat atttcctgat taaatacggt
    15061 aatttttatg tattgaatac tttaatttta gatgataaat taaaaactgt ctaaatttaa
    15121 tatgaaagga aatagtttaa tgctgacaat aattattgct ttacttcctg taatgggatg
    15181 gggattgatg cccatagttg caaatctaaa gaaaagttct cctcatgaac aacttttagg
    15241 tacatccata agtgcgttta tattttccac tataataact ctagttatac atcctgaaat
    15301 tacatttttt tcattttgta taagtatggt ttctggcata ttctggagtt taggacaatt
    15361 aatgcaattt aaagcaattc aaattgctag tgtatctaaa gtaatgccga tttcaaatgg
    15421 ttcacaatta acttttacga cattactagc tgtaatctta tttaatgaat ggacaagttc
    15481 taaaatgtta ctgattggtt ctttatcaat attatgtata atacttggta tacttctcac
    15541 aaattatcaa actaaaaaat ctacagataa aaatatgtta aaatgtgttg gagttgtatt
    15601 attatcatct ctatttttat cattatatgt tgtaactaat caaatatttt taattgaagg
    15661 atatagaatt atattacctc aatctgttgg tatgctgata acttcatcta ttattgtcaa
    15721 atatttttct aaagagattg tatccaggga aaacgtctta ttcaatttaa ttactggaat
    15781 attatggtca atagcaaatt taggtatgtt cataacgact aatacattgg gagttacaat
    15841 aagcttttct atctctcaga gttgtgtgat agtagccact ttaggaggga ttatattttt
    15901 taaggaaaat aagaacaaaa aggaatggtt ttctattctt attggtataa tgctaatcat
    15961 gtctggtgtc tttatgttga gtattataaa ataggtattt atttacacaa atcatataca
    16021 tttttataca tataaattaa ctgtttctat ttattaataa atttacctat atacttaaaa
    16081 taatagcata tgtatttatg aaattaaact atactctaaa tgtaagtata tttcattaaa
    16141 tacatatgct ataaattttt ctgtcaataa gagagtacaa aacatcttat attgtaaata
    16201 aatttaactt tataaattta ccaactaata ttgtattatt taatattaag tttttcatct
    16261 tctataagct tatctgcaac ccactctgca acttgacctg ttattttaat acagtgttct
    16321 tttctttcgg gagacataaa gttatcacca tcccacttct ttgtaataac tctacaacat
    16381 gtcgcaccat attctttttt aatataatca tgcaaccctt tagcatgttc aaacatcttt
    16441 ggattcatag cttcaccatg aactcttcca tatactaaac ctaacgccat ctcacctcca
    16501 gatattgctc cacaaagaca ttgtgctttt ccaagtccta ctggaaatcc tgatgctaac
    16561 ttagttatct ctggacttaa tggttgtcct aaagcattat ttattgtgtg aagaactgct
    16621 tcagagcaaa aaaactctcc tcttctaaag cattcttctg cagttgttct aacttctttt
    16681 agatattctt cttttgtttt cattttttcc ctccaataaa attaagctaa attaagtttc
    16741 tatggtttgt cttatgttcg tatatttata taaatattcc taccaaagac acatatttaa
    16801 taattcttat ttagctttag atgtagtttc agatttacta agatgtataa taaataaaac
    16861 taaaacatat aaaataatca ctgtagcaat tatctcttct aatttagaag catatgaaat
    16921 ccaacttata aaatgacctg atttagttaa atgaccattt attagtttca tccccattgc
    16981 acttattgcc atagggaatg taaatgcagc aaaactcgga taaaaaggca atcttaataa
    17041 ttttggtaaa tatcccaaga ctataatata aaacacaatt gataatataa ataacaagta
    17101 taatactaca ttatttttat ctgaaaaaga attaatatat ccagacaata atagtgaccc
    17161 tggtgcagct aatatagcta tacttggtaa agatggttca ggcatttcct tgattatcca
    17221 tactctcttc aaaattactg gtataagaac tatataagat acaaatccta tccaaaaagc
    17281 aattttgcca atcaaaagtt gattaaatgc tggagctgta acactagctg caactatccc
    17341 aacatagact atataccaag atggaaatac tgtttttatt gagaatttaa ttaggaattt
    17401 tttactaaat aggactatta acacaagatg acccacaact cctatgctcc aaatcataat
    17461 acctaattct aaagataatg gttttacata tgtggcaaat atcattgttg ccattgttat
    17521 agttggaaat gtacttgata ttaagggatt ttctaattgc tctttaacac cctttctaag
    17581 taatactatt ttgattatat aaattgcata taaaataaat cctataactc caattacatt
    17641 acgtaatgat tcactataag attgtaataa gttacctaaa gtaaatattg acaaaatcaa
    17701 acttgcaata ggtataggat atttttttaa taggttcaaa ttatgcctcc tttgttacta
    17761 aattatttat gttttaatta tatcaaaaag atggtcaaat tgacatatta tgaccatctt
    17821 tcttatatag aaaatatcta tcaaatttaa ttttattatt ataattatct atattcttaa
    17881 tatattaagt taattagtat atttatttta atcaaatata ctaatttgtt tattcttatc
    17941 tactttaata gtcttcatat ctctaatgct tatttttgca tcacctctta aagtatctat
    18001 gagtaattta ttatcttctt tataaagcct acagttttct tctacttttg cataattaaa
    18061 gttagcataa caatacagac aataatgtct gcaagtattg tattgcccta tatcgacact
    18121 ttttacacat ccacaaatat ctctttgtgt actatctttt tttacctcta cttcacatcc
    18181 tataattttt gatattaatc tatcatcaat acacttactt tttccaatcc caaatttact
    18241 taaattatat tcttcagagc acatttcaag tgttatccca tgcttatgag caatcttaga
    18301 aatctctttt gataatgttt ctatttctgt aatttctatt ggctttatat gtaatgcttt
    18361 agtattaaat tttgttttct tatataaatc gataaaactt attatacatt tttctgtaaa
    18421 tccatcaagc tgattacata aactcgcaaa tgctttgata tgataatcta ctgtgtactt
    18481 ttcacttaaa aaaatcgggt cataccttaa aattactctt tctttgccta tttttctagc
    18541 caattcctta aatgaatcta ttacctttct tttatctaaa atgcaggtct ctacttcttt
    18601 gccatatgat gttatagtat agtggaaata atatttatag tcttttaatt tatttaaatc
    18661 acatatcatt ggagtcacat cctttgtcca aaatacaaaa caatcaacag tatgtggatt
    18721 taactctatc ttactaactt gctttggatt cattggatta attacataaa caaaaccttc
    18781 tttaagtctg ttaaaaaacc acttactata gaaagcaggt atatcagttc ttctactcac
    18841 acttactatc atttttaacc tccatagtaa tataattatg ctctaatata tttttaatat
    18901 aattatagct ctaaatactt aatttaatca aaacatttaa gataattcca gtatgattta
    18961 ctgattcatt tctagcattt aaaatatcct taataagttt acaattcttt aaaaataaat
    19021 atatattatt cctaaacttc taaaactaat tttataatga aactaaaaaa ggtgctattt
    19081 tcaagcaccc taatccaatc tggagtttta gtttcaattt ccatgattaa ttcctccttt
    19141 ttaaatctaa attcttctca cagaaacaat tttgaactat aactgaagtg ccttttacta
    19201 tctttgggaa ttttgagaat agcactttca ttttcacaat attattataa ttttattata
    19261 tttttttata atctcattat attttcacta ttactaaatt actcttaatt ttttaatata
    19321 aattttgtac aatgattaaa atagttaagc tttatatcaa tataatctaa tcccaataaa
    19381 aaaaacactc atttctgagt gttctataca agtttttatt ttgagacatc ttatataatc
    19441 ttatatttta aaaagtttat aatatccaat ttaatatctt ctttagtaaa gttatttttg
    19501 atttgcatat cttagtgacc atggacaact catcatgcac ctcaatacac aaaaacactt
    19561 tgaaacatca ataatagact ccctttctcc tggcaaggtc cactcgtttc catgtatagc
    19621 ttttgcagga cagttttcta cacaaatatt gcaatctaga cattttgaat caatcaaagg
    19681 atgtctttca acagaaattg gagcgtctgt aagtactgta cacatactaa aagcacatcc
    19741 atattcctct gttacaaaca aattattttt ccccataaat ccaataccac taatatttgc
    19801 tattgtctta tgtggcaaag gactaatccc tgattgcatt tctggattaa tataagcttt
    19861 ttcaaaatat ccatgttcta gattattttt ctctgattga gaataagctc tatatccttt
    19921 actttgaata tattttgaaa tccaatcagc taacccttct actttctcct ctttttctaa
    19981 gaactcatca ctacctgtag gtaagttatt gtatatatct gtaataaatt tttttgataa
    20041 ccctatacaa aataaaattg ctttagagaa accctgtgtt tgacttgttg gaaattcaga
    20101 tatatcaaca aaacgaacaa tatctacacc tttactgtat aaaatagtct ttaattcatc
    20161 attcatgttt gactccttct ataggtaaaa acaaccttat atattaataa aattaactat
    20221 tctaattatg ttaaccaata ctttgtacat tctttatttc tactcataaa accatactca
    20281 attaaatatc ttctaattgt tgcaaaatca ccatatatag attctaaaat ctgattaact
    20341 tccttttccg aatattgctt cccacgttca aattgttcca aaatcttaga tagaattacg
    20401 acctttttct tttcttttga agaaaatact tttaatttta aaggattcat actttcaaat
    20461 gatgtatcta aaatgtgttt tctctcttct tcagttacta catatctttc atctaccatt
    20521 cgagcatgtt catgaattga tattatggtg ctacctttat tagatttatc ttcaaacaca
    20581 gattcatata gtgccaaata taacttagct tgttttgctt tttctctgaa cataaatttt
    20641 tgatgacgta tagtagatgt agacactcca accttttttg cgatttcctt atcaggtaaa
    20701 tcactaataa acaattgaaa taattgtttt tgattctcag ttaatgtgtt gtactttgaa
    20761 tcactattaa tcatttgctc taagtaatca ctatgttcta attccatatg aagttcaata
    20821 gcttttgaag cttcaaagaa tctattacct attttatata tttctcctat ttcatatatt
    20881 tttgtacatt taatacaact ataacaattc aaatcatcat taaatatata acctcgttta
    20941 atatcattaa tagaaagatt ttcaattttc atattactgt ctccatttca tattttttca
    21001 tttttataaa tatatcatat caaagtttat taatataatc aacattttta atttttgttt
    21061 ataaaatata attatttatt aatttaaaat cacaatatat ttcccacctt taatatcatt
    21121 acctacatta ttatgtattc atattgtgat ttgaatgatt agttattgta actggagtaa
    21181 taagtgatat cccctttaat tcaatcttag agtggtcaat tttcaaaatt ggagttcctt
    21241 ctttttaaat ttacatcagc taaatcaaag gctatcatta gttctaatta atatttaaca
    21301 ttttatgtaa aatttataaa aaaatgtata taaattaaga taagtgacta tactaaaaat
    21361 atgatacgga caaacaataa gttcaaccta tctcccccaa aataaaatga gctacagttt
    21421 cccccaactg tagctcattt tcatgtaatt taatatttta atttttctag actttttaca
    21481 aacatcaaat taccattagt tattccccat aattcatcag catataaagc aattctatca
    21541 aaagttgtag ttattatcac acatttatta tcttcagatg ctagtttata aaatatatct
    21601 accaaactct tttcaccttt atcatcagta ttttctataa tatcatcaca aattattaat
    21661 tcaggattat tagataatgc tctagcaata cagactctcc taatatcatc ttgagacaaa
    21721 tctttcactt tacaatttgc tttttcttta tcaattccta ctttttttag aatatcatat
    21781 acaatatcct ctttattctt tgctttattt ccagcaatca gcatagttag aacaatatta
    21841 tctaacacag tagcatcatt taataaatta tgatttttaa atatcgaccc tatatactta
    21901 cttctgtaaa tatttttatt aatatttttt aaatcttctc ccttatatat aatacttcca
    21961 ctagtgcaat catcaagacc tgatattaca gacaataaag tactctttcc tgctctattt
    22021 tttcctacaa ttacatacat ttttccaatt tcaaattctg cattaacatc ttttaataca
    22081 aacttactgc tgccttcata tttataatta acattaatta attcaagtat tgccaatcta
    22141 tatcacctaa tttctatcat aaattatttg tattggctta cacataattg cattatatat
    22201 agatactgta ctagtcaata atatcaatat cattgatata aaaattatct taagtataaa
    22261 atttaaagtt gatttgtctt ttaaattttt catctcttgt tcagtgttga tatcatttgt
    22321 attgacatct ttataactac ctttattaaa caaaaaatca ttatatgtta tattatactt
    22381 atactgatat tcaaaaacat aatttgatat tgatttctct gatatacttg caattcctaa
    22441 tccaagtaca gtagatatta agattatcat gatactttca taaataaagc ttctaattat
    22501 cttaaactta gacattccaa ttagtctcaa cacacatata tcatatttta ttttttttat
    22561 tgatatggca gaacttatca ccagcaatat tgaacctagc actaatatac caagagtata
    22621 cgtaaaaacc acaccagata agcgttctat tggtgccatt aatttatgat ataataactc
    22681 atctatagta actttataga tatcacttag acctttattt cttaattctt tctcaaaagc
    22741 ctttctacta ttagaatctc taagtaaaaa actagcactt gtataaatca ttttactttc
    22801 tggtctaacc cttttttcaa acgttactaa agtattatat gaggttaata tattgttgta
    22861 tatacttaca tcttgaacac tttctaattt attactatcc tttgtcttat atacacctac
    22921 tatgtttaaa tttaacttca cattagtgtt ataatcattt aataaagata ttgtatctcc
    22981 aaccttaaaa ttaccagcct ttagaaaatc ttcacttact atacattcat tatctttttg
    23041 aaatactctt cccttactta tatttaaatt gtaatactta agacttttat ttttatctgt
    23101 aaatcccatg actatgcaat ttgtagttat atcattatag tcaagttttt tatcattact
    23161 aggtgcatat tttttattat caacatatag tgcaaggttt cctgtaagtg acattttctt
    23221 tacgtatttt gattttgaaa agtttaaata atcttctaaa tttaaagggt catatccaat
    23281 taaagattct gttaaatcat tttgaacaac ttttttttca tcaattttaa tactaacctc
    23341 tgactcaagc tttttctcat atttttgagt tataatggac atatttaaat ttattattga
    23401 ggaaatagct attgataaga ccattaataa tatgataact atactaaata gactatgaac
    23461 tttatttcta atcaagtttt taattgcatt atttaaaata tacactttat atctcctctt
    23521 attaattaaa ttctatatta aatattttta taattcttat taactcttac ttgtattctt
    23581 taaacactaa ataaaaagtt gaacctttat tttcttcact ttcaacccat ataaacccat
    23641 tacataaatt acatacatgt tttactaaac taagacctat accataccca tctttattta
    23701 attcatttat tctatatcta tcataaaata ttttatctat atgatgctga ttcattccaa
    23761 ttccattatc ttttactgat acaatgacac ttcccttttg attttttaca tttatatata
    23821 tctctttacc ttcaccatat tttattgcat tatccaaaag attagataca cctctataaa
    23881 tccatttttc tctcccaaag atactcatat tttcatcttc atcaaaatca aatttcaaat
    23941 tgctatacac tttagaataa ttatcacata cttgtgcaca tattaaagct atatcaactt
    24001 catacatatc ctcattattt tttatataac ttattgcaag tacatcttct acgctatttg
    24061 aaactttatc aagaacattt aataattcct tatttccatc aagttctaaa ctcgttctaa
    24121 gtattgatat agcattcttt tgttcatgtg ataaatatga atttaacctt ttataatcct
    24181 caatatgaga atcgaattta ttttttaaat ctttatatac tctagacata atagggtcta
    24241 tactcagtat ttcattctca tcttcaatgt tatttatatt atttagtatt tctattcttt
    24301 ctttaaaatc caatcgattt aatattaata aaagtataaa gttagaggtt actataaatg
    24361 caaaaaatag tattataaca acattaaaat tattcttaag tataagatta taattagtca
    24421 ttaatccttt atctaaaaca taagaattgt ttagaggtat ttcactctta gataaagttg
    24481 tatctctaga aattaagttc ttatctatat ctgatatatt tataatatat tttaaaccta
    24541 ctgtgaaaat tataaaaact ataacagaat ataaaatcaa cgctatagtt tttttgtctt
    24601 ttaatccttg catatagaat atcctatccc tctagtagtt attattatct ctttacctgc
    24661 aacttctctt aatttctttt ttaatcgagc tatatgtacc cttaatacag atgataaagg
    24721 gtcaaaatat tcatcataga cgtgttctga tatatctata cctgacacaa tatcaggata
    24781 tctgcttgca aggtattcta ctatatcaaa ctcttttgtc cctaaagtta cttcttcatt
    24841 atatacatat acttttctag aggatggatt tattgtaatt ggacctgatt ctatattggg
    24901 gtttgttcta ccataaaatc ttcttataac cgcttgtatt ctagctctta attctataat
    24961 ttgaaatggt tttactatat aatcatcagc tcctaaatca agtccttttg caagttcgtt
    25021 tactccatct cttgctgtta caattattac aggtgtattt agattattac ttctaaaaaa
    25081 ttctaatatc tctattccat ctttatctgg caagtttaaa tctaataata tagcatcata
    25141 gtcatttaca aatgcttttt cttctccatc taatccacag ttagctatat ctactacaaa
    25201 ccctgcattt tccaaacctg actttatatt ataagaaagt tccttattat cctctattat
    25261 taatactctc atataatcat ctcctaaata aaatatcagt ttatttatta tatataatga
    25321 atgtttattg aatgttaact ttattttata agtatttata ttttaaacaa aacacaattt
    25381 tattattatt caaatgcttg tatttgtcaa atttaagatg aatttatcta atcatttagt
    25441 tattatcagc aatttaaaaa ggtgaattca tctaatagaa cccacctttt tcaattaaat
    25501 ctttattttg aaatagcatt tcttagtatt gagtgtatgt attaaaaaaa caatccctgt
    25561 aatctttatt aattttaaat atatctttca gtattgaatc cacaatcaat aacaacttat
    25621 aatgatttat tgtggatata aaaacttcat agttttatct agtgagcgtc aacaagcata
    25681 aactccttta ttttctgctt atctagataa gaaattgcac tggatacagc tgtttgacct
    25741 tgtcctgctg attttaaata ttgatatggt ttaccagcac aatctcctgc cacatataaa
    25801 ccttcaatat ttgtgttcat atttttatct gactttatat gagagccttc tacttctaat
    25861 cctggaacca tatattttgg tgatatacta tcttttataa tgaaaacacc atctatatct
    25921 aactcactct ttctcaatac taatttattg actagttttc caccttttat ttctaaaggt
    25981 ttatcatcta ttacatttat accactattg attttatttt ctaatttata cataggtata
    26041 tagtatacat tacttgctat ctcacttaaa aaatttgcct cttcttctgc ttcatagttg
    26101 taccctatta tagcaacttt tttatttcga tataacatag catcacatgt tgcacaatac
    26161 ccaactcctt ttccaagata tgcgtcttct ccctttatca tttttccata ttcaatacct
    26221 gtagctaata caactgtagt tgcttcatat acatgatttc cagaaactaa tgtaaaatat
    26281 tcacccatac tatatacatt gtttattctg ttttgagtta tctttattcc catatcatct
    26341 atatgatttt taaatttctc tttaagctct aaaccactta tattactaat tcctagataa
    26401 ttttctacag aaggagcttt tataagtttt tgacttatat cttcagttcc aaataaaatt
    26461 atgtttttat ttctaatttt agcatttata gcagctgcaa gccctgctgg accacttcct
    26521 attatcgcaa tatcgtatct cataatctct cctattttca ataacctttc cttttttatc
    26581 taaataatat atcgaaagtc aatctcatta gcaattggat acttatttat aaccacacaa
    26641 actcttatac tatataaaca aaaaaactca ttataatgag ttttttgttt atatatgatt
    26701 tattttaatt acatatatga ttcaactttg ttctttaaat tatccttagg cataaaacct
    26761 attaatctat ctacaggttt tccatcttta aatatcatca tagttggcac tgtggatact
    26821 tcaaattttt gagctagttc tatactttgg tctatatcta cctttaaaaa ttttgctttt
    26881 tcagccattt catctcctaa agcttcatat attggtgata acatcttaca aggtccacac
    26941 caagttgcaa agaaatctac cactactaat ccatctttat tttctacttc gtttataaat
    27001 tcattatgat ttattatttt tatcataatt tacatctcct ttattatttt cttgatatta
    27061 atatactacg acctgtgtaa tacttcaatt agtcactttt ttgtaacctt ctatttttgc
    27121 tggctttaat attatgataa gcatatttat aagattaaat gtttctaata tattttaatt
    27181 ttttcattaa tatagttgac attttttact ttagattata aaatcaaatt aataactaca
    27241 taggtagtta ctaaactttt atataaggag tttatctatg aatgatataa ttaatgaatt
    27301 acaaaatata ggatttacta aatacgaatc tcaaatatac atatcattat taaaggaaag
    27361 ccctttaaca ggatatgaga taagtaaatt atcaggtgta ccacaatcaa aagtctatga
    27421 aaatataaca aagctattaa acaataatat aattatcaat gttggaactg accctattaa
    27481 atatgtaccc ataagtccta atgaattatt aaaaaataaa aaagaagaat ttaataattc
    27541 tatggataag ttaaagaaca acttacaaat attaaataaa ggtaaaaata tagaatacgt
    27601 tttaaacata aagggagata aaaatatatt aaaaaaagca atagaaatga taaaaaatgc
    27661 aaaacaagaa attataattt cttgccctta tgaagaaatt cttgaattaa aaaaagaact
    27721 cctaattgct tacaaaaaaa atattaacat tgaaatacta cttttagaaa ataaaaatct
    27781 cgaaggtcta gataatattc atatccatgg aggtaataaa actacacttg aaaataaaat
    27841 gctttacaaa ggaattattt tgattgtaga taataatgaa atattgacag gaaacttatc
    27901 tgaaggcaac gaagccattt caatttggac aaaaaactct aacattttat atattggagt
    27961 tcaatacata aaacatgaaa tttatatttc agaacaaata aaaggaggtt ataaaaatga
    28021 acaagattaa gattaaacaa gttgatgctt ttacaactat accttttggt ggaaaccctg
    28081 ctggtgtagt tactaatgcc tctaatattt ctgatgaaat caagcagaat gtggctaaag
    28141 aaatgaattt atcagaaact gcatttgttt cagagtcaaa tgttgcagat tttaaggtac
    28201 aatttttcac accaggttta gaagttgatt tatgtggtca tgcaacaata ggtactttcc
    28261 atgcactttt ggaagaagga aaacttgatt ctaataagag tatattttat caagaaacaa
    28321 aagctggtgt attatctgta gagcttaagg aaataaataa tgaaaatata tttatgatgg
    28381 agcagaatac acctgaattt gaaaatttag ataattacag aaaagaactt gcacaaatga
    28441 taggtgtaca tgaagataga cttcttgaat atcctattat gaaggtaaat actggacttt
    28501 ggtggcttgt gtttggctta aaatctttag atgatttaaa aaatatctct ccagatttaa
    28561 ataaaatcaa aaaatttagt ggtgataata atataattgg cataacccca ttttgtatag
    28621 aaactataga taaaaagtgt gactaccatt taagatctat cgcaccatat gttggagtta
    28681 cagaagaccc tgtatgtgga actggaaatg cttgtgtatc atcttatata gtaaatcaaa
    28741 atattttaga caaaactagt tttattggtg aggaaggtaa ctttataaac agacctggaa
    28801 aagtatatgt aaatatagct aaagaaaata atgagataac ttctgtgaaa attggaggaa
    28861 gtgcttatac tgtcttaagt ggtgaaatta tatattaatc tcatccctaa taaaaacaaa
    28921 taaaaatact agctaactaa tgctagtatt tttatttgtt tatttttatt taataataat
    28981 actctaatac atattataat cacatatatt ataacattat atttagaagt aaaattttat
    29041 ttttactatt aattagttat aaatcaatct aatacaatat aattacaata gattaatcca
    29101 taaaacacaa taattactta ctgattattt atcatcctca acaagtctat ttaatgtctt
    29161 gtcaaataag aataataata tagctgcaac aaatagtatt actggaatta tagtatacac
    29221 tttaatcatc tcaaatttaa gagtaaatgc atatatatat ccgtatcctt gaccagctat
    29281 gaaagtagca aatgtccata ctcccataag aacacctagg agtttcttag gtgcatactt
    29341 acttacaaaa gagttaccaa gtggtgagaa taacatttca ccaaaactta atagtatacc
    29401 aaacatgatt atccacatta tactagcttt agcagtttca ggggctccaa cacctcttgt
    29461 aaactctgcc ccaacaagca ttaaaaatgc aagacctaag aatattaacc caagacctgt
    29521 ctttttaaat aaactcatat ctccttgtgg tctactagca agcttaaacc ataatgctcc
    29581 aagaactggt cctaatacta tacatacaag cgcatttaat gagtcaaacc aagcaagagg
    29641 aatatcaaat cctccaatag tcatatctac aaatgctgca ccataatcat aaactgcaag
    29701 ataagttaga taccagaata cccagaaaat tacagagaag aatgatataa gtataatagc
    29761 ccaaattctc ttcttatcca tacttgtaag aggagactta tctttttctt caactttttc
    29821 agcaactaca ccttctttaa aaggtctctt tcctgcattt ccaaggaatc tccatccata
    29881 tgtgaaccat attgcaccta ttacacaaag tacagctgct ataaagaaac attgagaaaa
    29941 tccaagcaca ccattttttg caaaagtctt ggcataaagt ataccaactg ctgtagttcc
    30001 aataaaagaa cctatattaa caaaagaata ctgtactgaa aatgctgtat caagttcttc
    30061 ttgattatca aaaagttgtc catttactgc agacacattt cctttaaaga atgcagtacc
    30121 aattgaaact aagattatca ttgcatttac catagaaact gtagttgcaa tagaaccaag
    30181 atagtatcct acacccatta taagcatacc tataggtata gtatacctag ctcctatcca
    30241 tctatctgat atataccccc caattatagg tgcaagatat gtgaatgcaa caaggttagc
    30301 ttgcattata gctgcttgtc ccttatctat tccaagtcca ccatgaatta cagctgttgt
    30361 aaggaatata tagattaaaa actttgcaga ataatatgct gctctttcaa atgagaaagt
    30421 tgttgagcag atataaaatc ccataggaaa tttacccttc ttttttactg ttgagctcat
    30481 aagtttaaat cctttcttaa ttatattttt atatttttac gttttatcca aactctttct
    30541 tttaatgaaa gatatggtta tattattttg taaaacaatt tgtaattatt attaagataa
    30601 ttgcgcattt atttgtatag tatatatttt catggaataa aattaatata cttctttagc
    30661 cataaattta aattatataa attacttgtt ttcatatatt tataaattag taccttaatc
    30721 atctaatacc atgaaaaaaa cttcgccata tgcaattctt atttttttac gtgatagtat
    30781 tttacaaact aaaatccccc ttttgtagca acttatgtaa ttacatttta gcgctttttt
    30841 aaaggagtct agaataaagc aacatatatt tattcaaata atgtttttat ttacttttaa
    30901 atttatatat tacttcaccc aaccaattct caacttaaat aaataaacta ctatctattc
    30961 acagattata tttatctttt acttattaga tttataataa acactgtgaa tctaaacata
    31021 aaaaactgtt attttaaagt gattacccat atattcgctt cgatactatt tgttaaggtt
    31081 atactattta tttataatat attattcata aaatacctta atctgaaaac tttttcacga
    31141 atatttattt tacacctccc actatttatt tcaccatgta aatcgtacca taaatatata
    31201 cttatatgca agaaaaaaat ctattaatcg acagtaaata attagaaaaa tttaaattat
    31261 atttgtcaag tatattatat aaaatatttt ctatgaaaat ataagttaaa ttaatgttca
    31321 gaatagtttt ttagatatga aatcttgatt ttcttattac tttacttact tgctcaaata
    31381 tatttttgta tgcagtatat aatagtcaaa tcgtacactt cttataactg cgttgatttg
    31441 aaaataatat taatagttaa tagaagaaaa aattcaaatt aatttttaaa aaaactataa
    31501 gttaattgaa tactttttta tgtacttaat tagttttata aattcaatta ttttctaaat
    31561 ttaggtgtga tttaccatat aaaaatgatt ttttatctta attttctaaa tataagtgaa
    31621 tgctatcatt ttaagtatct tataagcaat gtaactatat atatctaata actacttttt
    31681 taatatgctt aaactattta taagcaatta tatttatctg ttaacctaat aactttttca
    31741 ctaaaaaata acaatctatt caaaaataaa ctatagtgct tcttctactt tgtttcaata
    31801 aaatactaaa taaatttcgt acattcacaa tttttcaggc tacactataa atatacaata
    31861 tttatcttag ttataagtct aagaatattt ttagtcttat tttgtcgaat atttttaata
    31921 aaacttcata attctaagca tattttttac actgtgtttt catgtacaaa aataatactt
    31981 acaaataaac aacataaata aaatttaaat aagatggatt ctattcaaca tagtatccat
    32041 cttattcatt caaaacctaa aaggattttt tataatatta tacattttaa aatctaaata
    32101 actcattata gtatcaattt cacttaaagc ttacaataca cttattaatc ttactttata
    32161 ataaaaagta taaaaacatc tacaataaca atttaaatct ttaagaaatt atatcttata
    32221 gtaattcttc aatacaatca cccttaattt tttatataat ttaattatat actttatttt
    32281 actagaacta atacacataa ataatactta aaatagatta aataaaggat actaaaacac
    32341 tttattgagg tatatgactt gaaatatatg aactaacttc attaggagaa atatctaaaa
    32401 tagttgcaaa ttcttcattt aataaccttt cagcttcttt cattatatta tcatctgctt
    32461 gatgtgtttt tttaccaata gattttacat actctctgtt attgtctatg cttcttacta
    32521 attttattaa ctcttcacat ttaccacctc tgagtatttt tttaaattgc tcacttctta
    32581 atttttcatt atctatccat gaggtatcca tattaggaat atcatttatt aatgaaagta
    32641 cattaatttt agaaagcaac tttctcattg gtactttttc attatctaca ggaattttta
    32701 ttattgtatt attagagtaa ataggattca atacataata ctcttttttt attccatttg
    32761 taaatcgttc atttgttata tccatgactt tgcagactcc tgtcatacca tacattatat
    32821 aatcatcaat cttaaacaaa aacatcacca tccttaataa aaaaaaaagt tttgacaact
    32881 aaatccacct tgccaaaact atctgctata tattatatat taacacattt taagacttta
    32941 atgtaagtaa aacttatatt attaaaatta aaaaatacat caagcattga ttaatgtatt
    33001 ttttagattt ttataacaag catatcaaaa taaattaaga cagcttatct cctgtaaata
    33061 cctataaaat tggtgcttgg ctattcattg agtacccatc atttcttaca tcatttattt
    33121 ctaatatttc atcatttgtt tcaactttag taagtttttt aactgctcca taaggttctt
    33181 ttaatgaaat tttatctcct cttccagaaa taacccataa aattttatac cctctaggta
    33241 taacttgtag cttattttca cctttaccat cagtaaagta gactaacaag ttaatctttt
    33301 tattattagc atactcaaag actggagaaa atctagtacc tccacctatc ctaattctat
    33361 cttttatatc tttttcagtt ttcactttat atacacgtct aatttcatta tcacattcta
    33421 taattataat ttcatgatta tagtttttca ctatactaag aacttcttta atcgcttgtt
    33481 taaactcttc atcactaata cttccactta tatcaagtgc aactgctatt tctgccttat
    33541 gacttctaag ttctcccctc aaatctaaac gatttggttg tcttctattt cttcttgtta
    33601 tagtcttctt tttattattt tcaactgttc ccatcattct attaagatat aagttccatg
    33661 gcaattcact cttactattt ttaagtgatg atatcatact ttctaaataa gcaggaactt
    33721 tacctttttg agaactatta ataaattttt cagtaaattc tctaagggta ttttcatcta
    33781 tctcattaga ttcatcccat atatcatgag ttctttctgg actataatca atttctatat
    33841 ctccatattt atcactatca tcttcctcac catcttcatc cacttccatc aaatctaatt
    33901 cagtttgaat cttttccaca taatattcaa aaggttcata tggctcaagt tttaaggaat
    33961 attttaaatt tacccactct aaggtagttg catatggtgg taaattgttt agaaatttat
    34021 ttactactat atccattgcc atattaattg ccaatgtact atactttcct tttaactcct
    34081 ttgctctcat cagatgcata gataatatat gatgaatttc atgtttaatt gtagtctcca
    34141 tttgttttat atcaagcgtt aaaaaaatta ttggattaaa atatataaca tatttagccc
    34201 ccttaaaatt tacacctgta ggactactta tatcaaatct tatctctctt aacatctgaa
    34261 acaaaaaata tccataaaaa ttatcctctt cttccataag acttaaattc actttatcta
    34321 caagactaaa aaactcatac ttaaaatcct gtggtatatc tatatcaaat ttctcattag
    34381 cacgatttgc ctttaacata gaatgagtat ttataatttc acttgcttta tcataaagct
    34441 cttttgcttg tttatcaaaa taattttcca tacattatcc ccttattaaa ctataagatt
    34501 caaaatatga ttttacaaac tcttcatttt ctatagcttt tttatacact tcagtataac
    34561 tgtttctaat atccttcata atacctatca ttaagtccac aggatacatt tttaaaaatt
    34621 taataaatct attaatatag tgatttgatt catatttatc attcttaata tttagctcta
    34681 aatcttttag aatattcata gctgatagat aaagtcttgt atgactctct ttttttactc
    34741 tttctacaat agactcatca atagattctc ctaaaaaaac ttcttcatag gatattaatg
    34801 gtttagaatc tgattcaata aaacttataa attcttctgc gataacctta cctacattac
    34861 cctttataac atttaaaaat actgctctag gaatagaatt attattttct ttataaactt
    34921 tataaatttt agatactctt tcataacttc taggagtagc tcttacatca tcttcattta
    34981 ttttatgcag atattctgga aaagtggaaa taaactcgat aacttttctt tcaatccctt
    35041 catctattgc ccattttatc cattgtgtat ggtcactctc catatttaac caaacaaatc
    35101 tattttcttg agctgcatcc atatctacca cttgataatc aaaatctgaa ccatatttac
    35161 ttgatgggtt cattgccgct aaaatcttta catcatcatg caatttatat ccattaatct
    35221 ctctatttaa aattagattc ataagttctt gctgtactgt atgctcacaa cgatttatct
    35281 catctataaa taaaagaact atcttacctt tagatatctc ttcatcaatt tcccttaatt
    35341 tgttatgaac agcatatacg gttgttttct tttcagtctt atatccacta gaattaactc
    35401 ctacataaga ttctatagta ggaagacctc ctatttcacc ctctttaagt aggtttccat
    35461 caatagcaac taaactccaa tcattttctt tggcaagctt atttgccaaa gctgtttttc
    35521 ctatcccact ttcacctact attaaaggta cttctccagt ggataatatt aagtcaacgc
    35581 tttttaatgt gtctataaaa ttcattttta tctctcctaa acaatcttta atttctcatc
    35641 tacagctatt ttttttgccg ttttgcttcc atatttataa ataaacataa ttttatctat
    35701 tggtatattc tcactatgtc tatctataac actacaattt aaaaaatctc taatatactt
    35761 ctcttcaaca tcttcttttg ataatacttc ttttaatact tcctccaatt catctttaga
    35821 tattttcttt acaatgtatt taatcactaa gatattcact tttaaaaatt ccaacatttt
    35881 attcttatct aaatcagtta taaagctaat agctgcttca ttatttttta tagctataag
    35941 ttctgcactg taactaggtg aatctatata tctcaaggca tcataactta ttctcacagc
    36001 ctcctcttgt acactttcat aaggttgttt tataaacttt atcgaatcat aattttttct
    36061 tactgctaat aactgtaact cttcacttgg atttttaaca tatttaattg cccaacctgc
    36121 ttgatttata gccatttcaa taactttatc agttggattt ttgatataat ccagtatact
    36181 ccatccctca tttactgctt ttatcatcat ctcttctgtt ggattatcta taaatttaat
    36241 tgctctaata ttattatcta ttgctagttc ttgcatctct ctagttggat tatttatata
    36301 ttctagtaca agtccatttt ctttaatagc taataatttc atttcatcag ttggattatc
    36361 tatagttgat ataatattag gattattttt tatcatttca ataactcttg atttttccat
    36421 aacatgcctt tctttatata attatttttc tctttatact aattataata atttattcct
    36481 atttatataa ttgtttctta ttataattaa tatacttttt aagcaaattt aaacagaata
    36541 attataccaa tatataaaaa aatttctaga aatcaataaa attaagtcta tatacataaa
    36601 gacatcttta atatttataa agtcagacag taatttaata cttttattga caaaaaaaga
    36661 caatccataa aaaattgtct tttttcaaca aaattcatca atgtaatttc tagatatcgt
    36721 tgctatcccc atataattat tgaaattact aagatatagt attttgttat ttaaatataa
    36781 acttattcta acatctattt atttagatgt ttttccataa tatctaaaat tatctaatct
    36841 attgtaatac ttactttttg agatgatatt gttgcatttt catcttcaac ttcagcccaa
    36901 aaagtatgag tacctactat taatgaataa agtacaaatg atttctttac ttcattagga
    36961 tttctaacac ttagttcttc atttacaatt ttttgcccat ccatatatac atttaaagtt
    37021 tttgcattat tcattgctgg aacgattacc tcaacatcaa ctttattagg attaggtgat
    37081 atcttaattg atggtggtat tatactatct actattatat ttacttcttc agattttaaa
    37141 catttaccat tgccatcttc aagaactgca aaatatgtat aaaaaccttc ttttttgtca
    37201 ctcatatcaa aattaatatt ttgtaattct gaacttctta ctaaatcttt tgtttctata
    37261 ggaacattat tctcaaatag ttccaattta gtcgcagaat tattaggagg aacagaaaca
    37321 ttaatattaa atttaccatt attactcaag gttttatcag ttgatatttc tggagactgt
    37381 aaatataatt ctgatgaatt atcgatttga cccaaatcga acattttcga atcaccatta
    37441 atttcaacat ttttggagat taattcggga gatagtttat gccccttatt atctactagg
    37501 ataattgatt taataattgc tactttatca tcttttaaat tatcctttat ctgtaaataa
    37561 attttgtctg cacttgatag gctaacatta agttctttct ctaaatgtgc taaatcaatt
    37621 acaaaagtga tttctgaacc attatttaca ccatccaatg gaaaatctcc tccactataa
    37681 gataataatg gactgtatac tactgtttgt ttattaccat ttttctcata tactagactt
    37741 acttgcaact gttttctgtt atcatgttgc atagtgaatc tcactaattt ggatggtgtt
    37801 tcttttttgc ttattactac atattcagct tcattattta agaatgctcc ttgtcttgca
    37861 ttactatttg taaagtctaa aactgatgat tttttattta atgcatcata agccatccaa
    37921 acaaatccat tgtttgcata gtcaggtcca tgagaattag caatcttaaa agcacctttt
    37981 tcaccatcat caaccttacc attgctattg atatctatcc atatattgtc attgtatcct
    38041 acaatagtca tttcatgtgc accttgatta ttaatttgat aaattgcttt ctgatttaca
    38101 taactatcat cgtctttagt cgaggggtca ttagaaattt gtttataatt agcatctgag
    38161 aaccaagtat agaaatttaa aatatatcca tttagtaata atctcttcgc atcatccaag
    38221 tttgagtctt tgtttgatgt aataaaagaa tttggcttat tatttttatt aaaattaacc
    38281 cttaatattt catctacctg atatttagtt gcatttctcc agatattttc atctttagcc
    38341 cattccctat aatttttagg atctctgcct aaacctacat aaggaaagtc agctaatgta
    38401 gcacaaccat gtgttttaaa aacattataa ttctgataag caaatgctcc tgcatctttg
    38461 ccatcgttta tgaaattata agaccactta ggtgaaaata ttttagaatc tatatttttt
    38521 ccactcacat cttttacact ccaatcattt acaagagcag tcatataagt catagtatag
    38581 tatgctgttg cataggatgc acagcttgcc aaagaacctt ggctccctat gttaggaaaa
    38641 tacttagttt ggctattgtc aacatttgat ggaagtttaa tattttctga attgtcttca
    38701 agtgaaaaat tagaagtgtc tccttgttta actatttcat ctcctaattt tgctggagat
    38761 acattttcaa taatttgttt tgagttgata ttcttaattc tttctaatgc aatactattt
    38821 aaattaacct tttctgttaa tttagaaatt tccagttgct tagctctatc attgtcagta
    38881 aaatctggta accataattt ctcttctgaa ttgtaattat tttcataggc atgcaccaaa
    38941 aatttttgat taaatgttaa agttgtaatt gttgctagta ataatgctat tcttttcttt
    39001 ttaattttct tcaaattaat ccccccaatt ttactataca tttttgttaa aatttatttt
    39061 acaacacaat tttaattatt tcaataaaaa tatataagca aaaatgatat ttttttatga
    39121 ttaaacatag tatcaaaact aaaaacaata taaaacatct tgtatttact tggaaatagt
    39181 tagtttttaa aatgatttaa gatataataa ttcttatctg aatt
//
LOCUS       DAMKOJ010000034        38332 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000034 DAMKOJ010000000
VERSION     DAMKOJ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38332
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.036"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            164..676
                     /locus_tag="PC592_001860"
     CDS             164..676
                     /locus_tag="PC592_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDF4055835.1"
                     /translation="MSDFKEILAEEIKSNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QVGFNIEHLNNTPYFKEAKMALICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKEA"
     gene            complement(830..1891)
                     /locus_tag="PC592_001861"
     CDS             complement(830..1891)
                     /locus_tag="PC592_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDF4055836.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGKKIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(2015..2908)
                     /locus_tag="PC592_001862"
     CDS             complement(2015..2908)
                     /locus_tag="PC592_001862"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDF4055837.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIENGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPTGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLVSALINKNFELLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIRENDDSFVDNMRNYLQNL
                     KSDWEIKELYCDSNGAVLNIL"
     gene            complement(2918..4399)
                     /locus_tag="PC592_001863"
     CDS             complement(2918..4399)
                     /locus_tag="PC592_001863"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDF4055838.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSKFPNVKNELID
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVDNGEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLNDKGVYKISEDMEKNLASFHGEYSNEEEVKNTINSVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     misc_binding    complement(4507..4737)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5523..6431
                     /gene="trxB"
                     /locus_tag="PC592_001864"
     CDS             5523..6431
                     /gene="trxB"
                     /locus_tag="PC592_001864"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF4055839.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKIKIVKTSSAEHKAKA
                     VILANGVERRKLGCVGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARKNIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(6521..8344)
                     /gene="typA"
                     /locus_tag="PC592_001865"
     CDS             complement(6521..8344)
                     /gene="typA"
                     /locus_tag="PC592_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDF4055840.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEELSPLFKTIVNHVEAYPDYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            8556..8798
                     /locus_tag="PC592_001866"
     CDS             8556..8798
                     /locus_tag="PC592_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055841.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            8946..9137
                     /locus_tag="PC592_001867"
     CDS             8946..9137
                     /locus_tag="PC592_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDF4055842.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            9428..11929
                     /locus_tag="PC592_001868"
     CDS             9428..11929
                     /locus_tag="PC592_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF4055843.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYNPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMKNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKALFSLSPNMDSLVAIGTLAAFLYSLYTTIQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAVVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINNENILLGNRKLMNDNNIKLGDLEEKSNLLAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNVKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            12089..12757
                     /locus_tag="PC592_001869"
     CDS             12089..12757
                     /locus_tag="PC592_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055844.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGNTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            12741..14018
                     /locus_tag="PC592_001870"
     CDS             12741..14018
                     /locus_tag="PC592_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF4055845.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEVKADQERITKAINNIINNAIKYSPEESEII
                     IRLYDKNKRISKKNSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVIFTVEFKN"
     gene            14421..14642
                     /locus_tag="PC592_001871"
     CDS             14421..14642
                     /locus_tag="PC592_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055846.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(14930..15694)
                     /locus_tag="PC592_001872"
     CDS             complement(14930..15694)
                     /locus_tag="PC592_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF4055847.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSRPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            15967..16641
                     /gene="fsa"
                     /locus_tag="PC592_001873"
     CDS             15967..16641
                     /gene="fsa"
                     /locus_tag="PC592_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF4055848.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSATVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(16763..18157)
                     /locus_tag="PC592_001874"
     CDS             complement(16763..18157)
                     /locus_tag="PC592_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDF4055849.1"
                     /translation="MGIILKPKQFYITVIATIILYFSLNYNFNIKFSICLSFLTILIW
                     AIDSVEKTVVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFVSHENLEVNKIQFSYSNFKKELNLLNKEQKYVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     RENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWRFIGLEI"
     gene            complement(18236..19582)
                     /locus_tag="PC592_001875"
     CDS             complement(18236..19582)
                     /locus_tag="PC592_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4055850.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLRLMNTPESVFSQSKLYLTIIFGGILFSAGYNSVSAILRGLGDS
                     ITPLYFLIIATILNIVLDLTFIVVLKMGVEGVALATIIAQAVSFIISIIYLNKKHEVL
                     KFKIKGIIYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVIVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSRFFGTNGIWMGIPFGWTLGLIVTVIYYNKGRWKTKAIVNHRINK"
     regulatory      19832..19934
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            20028..21404
                     /locus_tag="PC592_001876"
     CDS             20028..21404
                     /locus_tag="PC592_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF4055851.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEVIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCIGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFM
                     NPEHAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPKNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSIVMIVLAIL
                     FIIKLWLL"
     gene            complement(21506..22651)
                     /locus_tag="PC592_001877"
     CDS             complement(21506..22651)
                     /locus_tag="PC592_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF4055852.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAEISVT
                     SLALIGEVNIQKQIKNIKSVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKTLTATNPKRAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MAKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRNGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELVDIIK"
     gene            22903..23610
                     /locus_tag="PC592_001878"
     CDS             22903..23610
                     /locus_tag="PC592_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055853.1"
                     /translation="MLKVINLSKSYKNKKVVNSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFENGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            23657..25252
                     /locus_tag="PC592_001879"
     CDS             23657..25252
                     /locus_tag="PC592_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055854.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKSDGREKQKIMGMILSAIIITG
                     LLIFYVTTLSLSLVDILKQINQMEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDI
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFMFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKIYPPIYYFVDALKTGSVVSFLAFIAISIIPFFMFVTLFAKKFKNINAK
                     MSEGYKSKTYKFKSQKTSRPSKALLKKEFKRYTSSFIYFLNSSASLLFLIVGAILILL
                     FGADKMGELLKLNIDFNFIKIQLLGVFFFIIVMNCTTYCSISLEGENLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMVITMLVSLAYVVILGGIYTLLGISFLNIYIILASML
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            25355..26437
                     /locus_tag="PC592_001880"
     CDS             25355..26437
                     /locus_tag="PC592_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF4055855.1"
                     /translation="MRKLSKKEKDFIQYGFLLFLICITTYLVLTTLDIKMIPKIIRLV
                     NKTYIFLGILIIIIYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLIEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKMFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYIHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSSIIPKELLGYSVLLYSGFVYYFILIVSGIFTFG
                     THYTLNSWKKETKVNSNLDKVIEKLN"
     gene            26586..26747
                     /locus_tag="PC592_001881"
     CDS             26586..26747
                     /locus_tag="PC592_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HDF4055856.1"
                     /translation="MKQDKKNEKQSEISKIKQSNDNKLEVAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            27089..28357
                     /locus_tag="PC592_001882"
     CDS             27089..28357
                     /locus_tag="PC592_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF4055857.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            28551..29339
                     /locus_tag="PC592_001883"
     CDS             28551..29339
                     /locus_tag="PC592_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF4055858.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSNLNLDYIKEDEDCVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMKQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASRDYRKAMSKVLLKRAIMEVI"
     gene            29339..29788
                     /locus_tag="PC592_001884"
     CDS             29339..29788
                     /locus_tag="PC592_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF4055859.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKAGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRVLDREITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVIAMKDELENPTDEEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            29792..32056
                     /locus_tag="PC592_001885"
     CDS             29792..32056
                     /locus_tag="PC592_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF4055860.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAVDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNNTVVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDIVIEETYYTQAQAHAMMETYRAYNYLDHTGRLVVV
                     SSTQIPFHVKRHLSRALELPSSKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKIDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKYLDNGKVRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLETSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGANKLGVDKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDKE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGHMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMAMNK"
     gene            32196..32504
                     /locus_tag="PC592_001886"
     CDS             32196..32504
                     /locus_tag="PC592_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055861.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKAKVFFKEK
                     QNQIEIDFVEEEISKLIENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGRVH
                     "
     gene            32790..33290
                     /locus_tag="PC592_001887"
     CDS             32790..33290
                     /locus_tag="PC592_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDF4055862.1"
                     /translation="MRKNNINIALTSAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLI
                     IASLWPTIINSIVVGLMLNIFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     IINIKF"
     gene            33343..34329
                     /locus_tag="PC592_001888"
     CDS             33343..34329
                     /locus_tag="PC592_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF4055863.1"
                     /translation="MSKIKRLTDVWTYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMAMLFALKSLQVYNYKSIEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANNSNDGEFKSINVTEFFRASSESLILNIKY
                     KFGNQILEKKICPIGIYLNKGAWFSPAYDCKIDKIILVHIDNVIDIKRTGESKKIHIN
                     LEEWLDEVYNNLYENRSTTKKIGETIYLNVLLTKEGVSKIKDSSYNLDMELNEDGSGT
                     ISTFIRVEDVDYYASILFLIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            34379..35101
                     /locus_tag="PC592_001889"
     CDS             34379..35101
                     /locus_tag="PC592_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDF4055864.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEIEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIKEIIKAISYMSNERRVLSIGMDCSEKENKEALE
                     LGREFKINNDSIFKFVNLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKEYSEMADILFDRMEYIGEEFISKKGIVFVEGSSEFSIMELNDLINNIQRKIEESYE
                     VIFSLYMKENLDGNIRIGLLYN"
     gene            35130..37064
                     /locus_tag="PC592_001890"
     CDS             35130..37064
                     /locus_tag="PC592_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4055865.1"
                     /translation="MSENIRVTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFGMGKKSEKYINENCNDKDFIKRFVSIKKGDYFLYKAYQNIEEKVKCNVSIGMVEE
                     DFENGYELSHILGHTLPVKWMYNFDTVSNCKVYTSEFYKLNNNDISSYLEIINSQDKK
                     SLRKRIEESENNKWYLKNYYYKNVDKCVNDEELFIQPTNLEQLENIKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSTLEDGYFFPVRWIEYEKENIDGNAWV
                     IFENNSMVEKYVKRFTNKIPLNTILYGPPGTGKTYNTKQMVYNLVNKTSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYDALKFEKKM
                     SFELEKDSLTLEAIKKRKKKLVLENIEYSDSFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFFLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPNYDLLSIIDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEELIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            37057..38325
                     /locus_tag="PC592_001891"
     CDS             37057..38325
                     /locus_tag="PC592_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDF4055866.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENIILEILPKLSLSDNLVKDREILLQMLSICNKIPII
                     MNEKIRLSLKNYNLLNFFIMYFIESMQIQMKKGIYFEYINKIENLNVIRGKILLSTYA
                     KEKCISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILNYFQNVD
                     LIYIDRKKLLDYKFCKNNDRFRDCYLLARLLLLNLSMDNSQDNEEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKSEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITTYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
BASE COUNT        14747 a         4374 c         6047 g        13164 t
ORIGIN      
        1 aattattaaa tatattaaaa aataagagtg tatctatata tttacttatt tgtaataata
       61 tatttaaaaa aatttatttt attttcaaaa ctagacttca tttataattt atcacgaaaa
      121 taaaaggaat ataaatataa gagaatgaga ggttataaga gatatgagtg attttaaaga
      181 gattttggca gaagagatta aaagtaatcc atttggattg ataggtaaag attggacact
      241 tataacagca gaaaatgaag gcaaagtaaa cacaatgact gctagctggg gagggcttgg
      301 agttatgtgg ggaaaagatg ttgcttttgt agtaataaga ccacagcgtt atactaagga
      361 atttatagat aatacagata aattttctct tacctttttt gatgaagatt ttcgtaaaga
      421 gctttcatat tgtggaaaag tatctggtag agaagaagat aagatatcac aggttggatt
      481 taatatagaa cacttaaata atacacctta ttttaaagaa gcgaaaatgg ctcttatatg
      541 taaaaaaatg tatagtcaga aactggaacc tcaatgtttt attgctgaag gtatagatgg
      601 aagatggtat ccacaaaaag attatcacac tttatatata gccgaaataa ccaatgtact
      661 tgtaaaagaa gcttagttat aaaggttaat actatctcta attaaataaa atctctataa
      721 aaggaaattg gcacaaaaaa gctaaggaag taaatatgtt gatacagatt aataaataac
      781 gtatttaaac tccttagctt gataaaattt taatttagat ttctttaaat tataattcag
      841 aaattaattc attgataacg tcttcaacag tgcttaattt gtcaatttta taggcatcat
      901 ttccacaaaa taaaagtgaa ttttcaacat ctcctttaac tgcattgatt agagcttgag
      961 aaatacagta aggtgtttct tttggattac aaggaattaa acaattatag cacttcttta
     1021 tttctggacg atttatttta acttcttcta taaatttatt tcttatggca cgtccaggaa
     1081 gacctacagg acttttaact atatgaacat cttcttcact agcatttatg tatgccattt
     1141 taaagttctc atgggcatca cattcataag tagcaacaaa tcttgtacca acttgtacac
     1201 cacttgcacc catgtctata tattttttaa catcactact agaagttata ccaccagcag
     1261 caactactgg tattttttta ccaaattttt ctccataagt atttgcaact tttaaaattt
     1321 caacaaattc cttatcatag tctatagaat ctatgttatc aagttcctcg ttagagtatc
     1381 caaggtgacc accagctttt ggaccttcaa caactattaa gtcagcagta gttttctctt
     1441 ttctatccca catttttaaa attacattgg cagcttttgc agttgaaact ataggtgcta
     1501 tttttacatt acttcccttt actaatgatg gtaacttgtt aggtaatcca gctccggata
     1561 ttataaggtc tacaccagct ttaacagctt cctttacgta tgtttcatat tctttcatag
     1621 ctaccataaa attaatacca ataataccgc catttgagat ttctttagct ttagaaatat
     1681 gtttttttat agctcttaaa tttgcattta tagtattagt ttcaaaatct tcctcatcat
     1741 atccaatttg aactccagaa attacaccaa caccaccaag cttagcaact gcaccagcta
     1801 gtgatgacct agatatacca acgcccattc caccttgaat tataggaact tttgcaacta
     1861 aatctctaat tattaactct tttatgataa tccctcctca atgtaaacat gtttaaagaa
     1921 ctagattata atacttaata ttattaccta gtcctaatta ttatactaca aattataata
     1981 aaagagtagt tatattttgt atagaagacg ataattataa tatatttaaa acagctccat
     2041 tagaatcgca atataactct tttatttccc aatcagattt taagttttgt agataatttc
     2101 tcatattatc tacaaaacta tcatcatttt ctcttattaa agacattata gtaggtccag
     2161 ctccacttaa aaatactcca atactattta attgttcaga tttttcaaca atatcattgt
     2221 agttttcaat tagagttcct ctataatctt gatgcaattt gtcttgacaa gctactttaa
     2281 gaagttcaaa gtttttgttt attaaagcag atactagtaa agcaactcta ctaacattga
     2341 ataccccatc agaatatggt atttcctttg gtaaaacacc tctagctttt tctgttgata
     2401 atttgaaatt aggtatcatt gcacaaaatt taagttcttc aggaattttt ataatatcat
     2461 agtgtatatt ttcattatca gtaacagata caatcatatt tcctaaaata gcaggagcaa
     2521 cattatctgg gtgaccttct atttctgaag ctatatttag taattgattt ttatctaaat
     2581 tagcacctga tagagcattt gcagctataa cgccagctac tatacaagag gcactactac
     2641 caagacctct acatataggc acttcacttt ggatttttat tttgatacca gtaggtattt
     2701 tttctggttt aactctatcg aaaaagtact tcatagatgt ataaactaag ttattttcgt
     2761 ttttgtaagc gtcttcacaa ccttctattt caagaccatt ttcaatttct tcaacataaa
     2821 atttattgta tatatttaac gcaattccaa gacaatcaaa tcctggacct atattagcac
     2881 ttgttgcagg aactataatc tctaacataa taatcaccta tacctttaag aattttttta
     2941 tagctagttt taattcatct ttttcataaa tatctttatg tagtatttct gcatttttaa
     3001 gatttttaat aggttttggt atatctattt tagaaatact tgataatcta tcaattatag
     3061 caaagtcatc aaggtcttta aaatcacaat ctatagattt tagaacatct tcagaaaact
     3121 tgaatggact tgcagtactt acaataacag tttttgtgtt atcagaagtt tcttttttat
     3181 atttttcata acaattatat gcaacagcag tatgagtatc tatcaaataa ttataatttt
     3241 taaacacgct gtttatcgtg tttttaactt cttcttcatt tgaatattct ccatggaatg
     3301 aggctaaatt tttttccata tcctcactta ttttgtaaac tcctttatca ttaaggtctg
     3361 atagcagttt atttacaata tcagtatttc tatttgatat ttcaaacagt aatcgctcta
     3421 aattacttga gattaatata tccatagaag gagaagtagt taatttcaat gttctatttt
     3481 tatcatatac accagtttta aagaaatcat aaagaacatt attatcattt gatgcacata
     3541 tcaatttgtt tattggaaga cccatttgtt tggcataata tccagctaga atattaccaa
     3601 aattaccagt tgggacaaca aaatttattt tatcatttaa atttatttcc ccattatcaa
     3661 ctaatttcat atatgaataa aaatagtatg caacttgtgg aagaagtctt cctatattaa
     3721 ttgaatttgc ggaagataat atataattat tatctaataa tttttgatta aattctttat
     3781 cagaaaaaat cttctttaca cctgattgtg catcatcaaa atttcctttt ataccaacta
     3841 catatgtatt ttttccagtt tgagttttca tttgaagttt ttgtactgga cttacaccat
     3901 cttctgggaa gaatacaatt atttttattt tatctatatc tttaaatccc tcaagtgcag
     3961 ctttgccagt atctccagat gtagcagtaa gaatcacaac atctttctct aagttatctt
     4021 tctttataga tgttttaaga agatgaggca ttatagtaag tgccatatct ttaaatgcta
     4081 aagttggacc atggtacagt tccaagaaat aagtatcatt tactttattt aacggagcta
     4141 tactactgca atcaaacttt tcatcatatg cattttctat acaattttta atttcatctt
     4201 cagtaaaatc acataaaaat ttactaagta caaaaaatgc tatctgagaa tacgttaaat
     4261 ttactaaatc tataagttca ttttttacat tgggaaattt acttggaaca taaagaccac
     4321 catcatttga tattcctttt attattgctt gtgatgcagt tactttttct tcggtgcctc
     4381 ttgtacttga ataatacatt ttttataacc ctccatatat tttaaatttt taattagcta
     4441 attaagttag atacagaata ttttaaaaac tgaatttagg taataaaaaa agaccctcat
     4501 ccctaagaaa gggacgagaa tctatttccc gcggttccac ccaaattgat ttaaaaaaat
     4561 ccacttgata ctttaacgta agtaataaaa cgtctattcc tactaaaatc ataaagataa
     4621 cttcagatag aagctcatag gtagttttca atccttctaa ttatggaaac atttcagcta
     4681 gtagtttcct tctctggtaa tcgattcaga tttactcttc ctaatcaatg cctttcaata
     4741 ttcttaatat tattaattat tctagtttat aaaacagaca aagtcaagta ttaatataaa
     4801 aatttggaaa aaatattttt taaattgtaa aaaaattgta atcaaattga gtattagaaa
     4861 aataattttt taactttttt aaaagcttaa aaacctagat tttcatagtg atgaagctgt
     4921 ttttagtaaa agtaatcaaa agataactat taaatatctg taatattaca attttatatt
     4981 acactatatt acaaaaaaag tttacaaaac tttaatttga aaaatgtaat tatatggtat
     5041 atcatataaa tataagtaaa tagtgctaat atttaaacta ttaatcataa ttggttcaac
     5101 aaaagtatat agttaataat gtttaatttg aagaaattgt cagtgtaaaa ttacatatat
     5161 attcaaatta aattcataaa tatttcacat aataatagta tactgtaaac aaaaggaggt
     5221 attaaatatg ggaatagtac ttataacagc agcattagtt ttggttatgt atggactttc
     5281 aattttatcg tatatatcag aaagcaatat attagaagac actgtaaatg ataaccaata
     5341 aggttttgaa ttatataaat aagtgagaac tgtaaataaa agttaatttt tatttgcagt
     5401 ttttttatat atatgtaaaa taaagttaat taataaaaaa taatgtttta tttatagtat
     5461 atatggataa taatagtaaa gtataagagt aatgagaata atatataaga gaggtaaacg
     5521 ttatggtaga tatcattgta attggtgctg gaccagcagg tttaacttca gcaatttatg
     5581 ctatgagagc agggctaagt gttacagtat ttgaaaaaaa tatttatggg ggtcaagttg
     5641 caagtacctc tgaggtagaa aattacccag cagttcagaa gatttctggg gtagaatttt
     5701 ctaataatat atacaatcaa gcagttgctc aaggtgttga tattcagttt gatgaggttg
     5761 aagaaataaa tctagaggga aaaataaaga ttgtaaaaac ttcttcagct gaacataaag
     5821 caaaggctgt tattcttgca aatggagttg aaagacgtaa attaggttgt gtaggggaac
     5881 aagaatttac aggtagagga gtatcttact gtgcaacatg tgatggagca ttttttaaag
     5941 ataaagaagt tgctatagta ggtggaggaa atactgcatt agaagatgct ttatttttag
     6001 ccaacaattg cacaaaggtg tatttaattc acagaagaga tagttttaga ggtgaagaag
     6061 tgttggaaaa atctgtgaaa gcaagaaaga atattgagat actttacagt catggtgtag
     6121 aaaaaataga aggagaaaag actgtatcga aaatagaggt aaaaaactta aagactgaag
     6181 aaaaaagaac tatagatgtc agtgggattt ttattgctat aggtcttaaa cctaataata
     6241 aaatgtttga aaatgttctc gatttggatg aaggtggata tataatttca gatgaatctt
     6301 gtacaacatc tgtggaaggt gtatatgtag caggagatag tagaactaag tttttacgtc
     6361 aaataataac agcagcatca gatggagcta ttgcagctgt tcaagcagct aattatataa
     6421 atgttgaata gtataaattt caaataaaaa tagccatata aactgaaata atttttcagt
     6481 attatatggc tattttgcta actagaggta aatgtatgtt ttatttacct tgtctagatt
     6541 tattatatct taatctatca tgttcattta agaatctttt tctaagtctt atagaatcag
     6601 gtgtaatttc aactaattca tcatcttcta taaattctag agcttcttca agagtaaata
     6661 ttctaggagg agataatttt atagcatcat ctgaaccaga agcacgtacg ttactcattt
     6721 tcttgttttt acaagggttg actaccatat catcttttct agaattcatt ccaattatca
     6781 taccttcgta aacttctaca ccagggtcta cgaacattac agctctatca cttaaggcat
     6841 taagagaata tcccatagta acaccaggtc cttgtgctat taaaacacca tttcctcttg
     6901 aaggtatttc tcctttaaat tcttcaaatt tttcaaatga acgaactaaa gtaccttctc
     6961 cacgagtagc atttataaat tcacttcgat atcctaaaag accacgagta ggtgctaaga
     7021 actctatttt tacatagtct ccttctattg acatagactc catcatacct tttctcatgt
     7081 ttaattcatt tataatagta ccagagtaaa cttcaggaca gtttacaaca actctttcta
     7141 ttggttccat tagttttcca tcttctttat gcattaaaac ttcaggctta gaaacaccaa
     7201 cttcataacc ttcacgtctc atattttcaa gtaatataga taagtgaagc tctccacgtc
     7261 cagaaacttt atatccatca gtagtatcaa gaggttcaac tttaagacca acatttactt
     7321 caagttcctt ttcaagtcta tctttcaaat gtctagttgt aacgaatttt ccactttttc
     7381 caacaaatgg agagtcattt actaagaagt tcatagaaag agtaggctct tctattttta
     7441 tcatttccat aggtagtgga ctatctaaat cgcatatagt ctcacctata gagatatcag
     7501 gtataccagc tataacaact atttctccac tagtagcttc atcaacctca acttgtttta
     7561 aaccttcata cacagaaagt tttgatactt ttcccttaga tacaacagaa tcttctctac
     7621 atatagcaac ttgtgtatta tttttaagag tacctttgta aattctacct ataccaagtc
     7681 tacctacata atcatcatat gcaagagctg atatttggaa ttgtagaggt tcattatcgt
     7741 aatcaggata agcttcaacg tgatttacaa tagttttgaa tagaggagaa agttcttcgc
     7801 tatcatcatc catttccagt ttagcaatac cttgtttagc aataccatat attataggaa
     7861 attcgcattg ctcatctgtt gcatttaagt ctacaaataa atcgaaaact tcattaacta
     7921 cttcttccgc tctttggtct tttttatcaa tcttgtttat aaataatatt ggttttaaac
     7981 cgaactctaa agatttttgt aaaacgaatc tagtttgagg cattgggcct tcactagcat
     8041 caactaatag aataactgtg tcaacagttt tcataacacg ttcaacttca gaagaaaagt
     8101 cactgtgtcc tggagtatca actatgttta ttttgtaatc ctcatagttt attgcacagt
     8161 tttttgaata tatagttatg cctctttctt tttcaaggtc gttactatcc ataacgcagt
     8221 ctttaactac ttcgttcttt ctaaaaacac cactttgaga aaggaaagca tcaaccaatg
     8281 ttgattttcc agcgtcaacg tgggctataa ctgcgatatt tataatttta tgtttttgtg
     8341 acatttttgt tgctcccttc gattaaaata acttattaat tatagcacaa tatgttatta
     8401 ggtacaagga ggaatatatt aaattgtatt aatatagttc aaattggata aaaatgttag
     8461 ttttatatcc gaaaattatt ctgtttaaaa aaatttttta gacaaataat aaccttaata
     8521 gatgaaaaga ttaataaaag agtaaaggat gatatatgtt ggaagtaacc aaaataataa
     8581 ttaaatattt tgcaagtgaa agtgatactt ttgtaaaaga agaagtttgc aattttgaag
     8641 aacttcttaa atggtctcat aaatttattg aaggtaaaaa gatagaagat gttttgtata
     8701 taaaatctaa agaaaactat aaagtaaatg taattaagtc tttagaaatt aaggaattgg
     8761 aaatagtgag aaaacaacag ataccaccgt acatgtagta ttaataatat ataaaattaa
     8821 tgtgtaatac ttatattagg ataaatatgg tatgtatggt aacaatttat ataaaaaaaa
     8881 cttttataaa gtttatattt gggtataaaa gtattaatta gacattaatt aggaggaact
     8941 taaatatgat aagagtatgt ccaaactgtt caaatgtgga tgtaaataag ctaaaaactt
     9001 tggttggaga agaaaatgta aaaactggtt gtataggtca gtgtagagca ttcaaaaaag
     9061 aagctgttgg aataatagac aatgagcttg aaataaagga aacagaagcg gagttttttg
     9121 aagcttgtaa agaataaatt ttaaataaaa tataaattat aataaataga gcgtataaat
     9181 tgtataaata ttaaacaatt tatatgctct atttttatgt atatatttaa ttataagtat
     9241 acttttttat taaatacaaa taaatataac taatacattt atttataaaa aaaagattga
     9301 tttaatatac ctacaggggg tataataaaa atatagattt ctaaataaat aatttatcaa
     9361 tactacatat cagaataaaa cgttacaaat tagttgaaaa tatgttgaaa gaaaggaaga
     9421 ttttattatg agttcaaata aagtggtaga aagttacaaa attacaggta tgacatgtgc
     9481 agcttgtgca aaggcagtag aaagagtaac taagaagatg gatggagtgt atgaccaaag
     9541 tgtaaatata gctactgaaa aacttaaaat agaatatgat aattctaagg ttaattttga
     9601 tgatataaag caagttgtag aaaaagcagg atatggaatt ataaaggaag aaagtaataa
     9661 aaaaattgat atgaaaattg atggaatgac atgtgcagct tgtgcaaaag ctgtagagag
     9721 agtggtaaaa aaattggatg gagtagaaag tattagtgtg aacattgcaa cagataaagc
     9781 taatatagac tataatccat caaaagtaaa gttatctcaa ataaaagcag ctattgaaaa
     9841 agctggatat aaaccaatag aagaggtaag aaataaggtt gatgtggatg aagataaatt
     9901 gagaaaagaa agggaaatga agtctttatt tgttaaattt atagttgcaa tagtatttgc
     9961 agtacctttg ttttatatag caatgggacc tatgataata aagcctatag ggccatggcc
    10021 tttgccagaa attataaatc caatgaaaaa tacttttaac tacgcattaa ttcagttaat
    10081 tttagtaata ccagtaatga tagctggtta taaattttat ataaatggat ttaaagcact
    10141 tttttcttta agccctaata tggattcttt agttgcaata ggaacattag cagcattttt
    10201 gtatagttta tacacaacaa tacaaatagc aaatggtcaa attcaaggta tgcatcatca
    10261 tcagttatat tatgaaagtg caggaataat aatagcactt atcttacttg gtaaatattt
    10321 agaatcaaaa tcaaaaggaa aaacatcaga agcaattaaa aagcttatgg ggctacaacc
    10381 taaaactgca gtagtgttgg ttgatggtaa agaagttgaa actcctatag aagaggtaga
    10441 aataggagat atattattag taaaacctgg aacaaaaata cctgtagatg gagttgtaat
    10501 agaaggatat acatcagttg atgaatcaat gcttacaggt gaaagcatac cagtagaaaa
    10561 gaatgttgga agtaaagtga caggagctag tattaataaa aatggtgtta ttaagtttaa
    10621 ggctgaaaaa attggtggag atactgctct tgcccaaata ataaagttag ttgaagatgc
    10681 acaaggtaca aaagcaccta ttgctaaact tgcggatact gtatctggat attttgtacc
    10741 aatagtaatt gcaatagctg tagttgcatc attattgtgg tttttaatag gaggaaaaga
    10801 tatagtattt gtacttacta tatttatatc agtacttgta attgcttgtc cttgtgcatt
    10861 aggattagca acgccaactg ctataatggt tggaactgga aagggagcag aaaatggaat
    10921 cttgataaaa ggtggagagg cactagaatc tgcacataaa gtaaatacag taatatttga
    10981 taaaacaggt actataacag aaggaaagcc aaaagtaaca gatatagtat taaataataa
    11041 tgtaaaagaa gagtatctta tcaagattgc ttcaagtgca gaaaaaggtt cagaacatcc
    11101 tcttggagaa gcaatagtta agtatggaga agagaagaat ataaaatttg aaaaagttga
    11161 caattttaaa gctataccag gtgcaggtat acaagttact attaataatg aaaatatatt
    11221 acttggaaat agaaagctta tgaatgacaa taatataaag cttggggact tagaagaaaa
    11281 atcaaattta ttggcaagtc aaggtaaaac acctatgtat atagctgtag atggaaattt
    11341 atcaggtata atagcagttg cagatgtagt taaagaaagt agtaaaaaag caatagaaat
    11401 acttcatgat atgggaataa aagttgcaat ggtaactgga gataatgtga aaactgcaaa
    11461 tgctatagca aatcaagtag gtatagatat ggttttagca gaggttttac cagaagataa
    11521 gtcaaaagaa gttgaaaaac tacaaaatca aggcaagttt gttgcaatgg taggagatgg
    11581 aataaatgat gccccagccc ttgcaaaagc ggacataggg atagcaatag gaagtggaac
    11641 ggatgtagct attgagtctg cggatatagt acttatgaag agtgatttaa ttgatgttcc
    11701 aacagcaatt aaacttagtc atgaaactat aaaaaatata aaacaaaacc tattttgggc
    11761 atttggatat aatacgattg gtatacctgt agcagcagga atattgtatg tatttggagg
    11821 acctctgtta aatccaatga ttgcagcagc agccatgagc ttaagttcag tttcagtcgt
    11881 atcaaatgca cttagactta aaaacttcaa ggcatacaag agagactaga ttaacaagtt
    11941 aaaaagaatg tatccaaaag agctatcttt aaattaaaag gattaattta caaattaaga
    12001 tagctctttt ttcatgtaaa attcacaaca ataagataaa atataagtaa tatatgaaat
    12061 tttaaataaa atagaaagga ttgatagaat gaattcgtca atacttgtaa ttgaagatga
    12121 ttcaaatata caagaattaa tatcagaatt tttaagtgca gaaggttatc aagtggatac
    12181 agcaaatgat gggttggaag gtatacaaaa gtttaagcaa ggaagttatg atttagtaat
    12241 attagatata atgatgccaa atttagatgg ttatggagta tgtaaaatga taaggaagtc
    12301 atcaagcgtt ccaattatat ttttaactgc tttaaatgat gaaggagacc aacttaaagg
    12361 gtttgactta gaatgcgatg actatataac aaagccattt tcatttaatc ttcttataaa
    12421 aagagtagag gcaattttaa ggcgaagtaa caagactata aatgacaaat ttatagtttt
    12481 tgaaaaatta aaattagatt taaacacata tattgcagaa atagatggag aacctataga
    12541 acttacacta aaagagttta atatattaaa agctttgata gaaaagtatc cacaggttat
    12601 aactagagaa ggtcttttgg atagtatatg gggttatgac tattatggaa atactaggat
    12661 tgttgatgca catataaaaa atataagaaa aaaaatatca ttaccatata ttaaaactgt
    12721 aaaaggaata ggatatacac ttgagaagga tatttgataa gtgggaaaag ttaagtataa
    12781 agtataagtt attttcaata acgacatcat tattaatagc attagcttta ataatatatc
    12841 taattttata ttttttattg ccatcatatt atcatgagta taaaattgag tctcttcaag
    12901 aaagtttaaa gtctttagtg gatagttcaa ttcatttcga tacatatact ttggaagaaa
    12961 gactttatta tatggctaaa gaccaaaatt tggctatttt attaaaagat aaccaaggga
    13021 aaattgtata tggtaagaat gaagtagtta ttttaagata tagtaagtac atgattaata
    13081 gtcttgagga tgagtatagg acttctatac ctatatatac taaagatgca aaagatgggc
    13141 catatacttt agagctcgtt atgccattac aaccaattga cgaagcaaac gaagttataa
    13201 gaaaactgat gccgtacatt atatcaatag caatattgat agcgattatt ggggcatata
    13261 tatattcaat tgtaataaca aaaccgctta taaatataat agagagtgag agagagcagg
    13321 aatatagaag gaaggatttt gtcgctacaa tatcacatga actaaaaact ccaataacca
    13381 taataagtgg tcaaattgaa ggtatgattt acagtgtagg taagtataag gatagggata
    13441 cttatctaaa aaaatcgtat gaatgtaccc aagaattaaa agatttagta aatgaaatga
    13501 tagaggtttc aaaatcagaa atacttgaaa aagatttgaa attggtatca ataaatataa
    13561 gtgaattatt aaatagactt gtaaaaagac aagtattttt aatagaagaa aaacatatga
    13621 aaactatttt aaaaatagaa gaaaatttag aagttaaggc agaccaagag agaataacta
    13681 aggcaatcaa taacataata aataatgcca taaaatattc tcctgaagaa tcagagatta
    13741 taattagact ctatgataaa aataaacgaa taagtaaaaa gaactctaat caaagagtgg
    13801 ttttagagat tgaaaatact ggtgtaacta tcgagaaacg ttatttagaa gagatattta
    13861 atccatttta tagaatagaa aaatctcgtt caagaaaaac tggaggaagt ggactgggac
    13921 tttatatagt cagccaaatt tttaaaagtc atgggtttga ttatagcata aaaaacaaag
    13981 aaaactctgt aatattcacg gtcgaattta aaaattaatt acttattata aagaatatat
    14041 aactttcaat aatagttcat tttaaaatca caaaaaattc atactgaaac tgtattatat
    14101 aaatataaag aagctttaaa ccataaaata caccaactat aatgatgaga tttccttaca
    14161 tcctccatag aagtcatcat tatagtaacc caacaattaa gttactatga atttaaaaaa
    14221 taacaccaga catataatct atgtttagtg ttatttttat tttgaaataa aaaatttcta
    14281 atttattgaa atgtatagat ttagatagtc ttaaactata tttaagggct taaaaattat
    14341 aattgatatt acaaataaat atatatactt tgggaaaaat aaatatagaa agtattatat
    14401 ttaaagagga ggtagttttg atggacagat taaaaagaga tatgaaaaat atgaaagaag
    14461 atttaaaaga aggagttaaa aagacagctt atgttatgaa aaatacagct gaagatttga
    14521 aagatgatgc acaaggtgct atggtaaact tagaaatgaa aaaagatgag atgatggaaa
    14581 gatatgaaca aaagaaattt tctaaagaat tagaaaagca aatgaagaat gaaatgaaat
    14641 aagtttttat ttatgaataa caaattattg tgttcatata aaaagtagct agtaatatta
    14701 aatagtttat ttaaggaaat agactttcta aaaataactg tattagattt agaaagtcta
    14761 tttcaaatta gttttatgaa tagacataag gataaaatcg atattataga actaaatttt
    14821 aaaaaataga tacaaggata aaataaatat tatagaaata tgtttttaag gatagctatc
    14881 aaataaaaat ttatgtttat aagaaattct ataaaatata taattaaact tataaaacat
    14941 ttacattaaa ttctgataaa atatctacta tatcaggagt aggcgttttt tctgtaatta
    15001 tagaactaat atcttctaga tgagcaaact tgaaatttcc atcaaattta aattttttat
    15061 cttccataac tataaatact tttttacttg aatttattat agccttcttt gtaagaccat
    15121 cttcaatttc aaaagttgta agtgaagagt tgaatacatc tactccgcaa cttcccataa
    15181 aagtcttatc aaacttatat ttggatataa actctatagt tggagtaccg acaaacccat
    15241 ctaaactgag atttaataaa cctccagtgg aaattatatt taaattgttt ggtcttgaag
    15301 taactacatt tagtatatcc aacatatttg taacaagtgt taccttttta ttactttcag
    15361 ctaacagttt tgcaagcaat atgttaattg tagagatatc taaaaatata gtttctctat
    15421 cttcaattaa attaaatgct ttttctgcta ttattttctt tgttgggata ttaatttctt
    15481 ttctgtcttt tgtatcctga ttctctagtg tttctctagc tagtacagct cctccgtaaa
    15541 ttcttcttat tgaagaaatc ttttctatat tttttaaatc ttttcttata caatcttctg
    15601 taacattaaa tttagaactg agctctttga cagtaactct accttctttt tttaggatat
    15661 ttaatatggc ttgaattctt tcttctgcaa acattttcta cctcttttcc aaatatagta
    15721 ttatagtaaa tattataaga taaaatacaa tatatcaact attttaacat gaaatacaaa
    15781 gttaatttaa tataaaaagc atattttttc taactatcta tttacgattt agtaaataaa
    15841 gaaattataa aattaagaag aaaaataaaa caataaaaaa aaataaaaaa caataagcaa
    15901 aatgttgaaa ataatgccaa accaatatat aataagaata aacaaagatt aaagggggat
    15961 attttaatgc aactaatctt agatacaggt aatgtggagg agattaagga gttatgtact
    16021 tgcttaccaa tagatggtgt aactacaaat ccaagtattg tttcaaaaga aaaaaagaat
    16081 tttaagcaac ttataaatga aattggtgag attataggtg aggatatgcc tatacatgct
    16141 caggtattaa gtacaaagta tgaagaaata ttagaagaag cattatatat aagtagtttg
    16201 agaaaaaata tatatgtaaa aatacctgta acacaagatg gtttaagagc tataaaagac
    16261 cttcacagaa aaggtgtaaa aataactgct actgcaatat ttactgctca tcaaggcttt
    16321 ttagctgcaa aggctggagc aaattatatt gcaccttatg taaataggct tgataatata
    16381 tctggtgatg gagtagctat ggtttcagaa cttataaaaa taatagatac ttataaaatg
    16441 gatacaaaag tacttgcagc cagttttaaa aatgcacaac aagttataga attaatgcaa
    16501 catggggtgc atagtgctac agtaccatat gatatttgta aatctatgat gaatcatcca
    16561 ttaactgatt ggagtgtaga taagtttata gaggattggg agaatacttt tggaaaagga
    16621 agtaaaacaa ataatattta gtattatggt aaaaaagcag ttttgttcaa tttcacaata
    16681 acttgtataa aaagacgaaa atatgaattt tctttttaat aattccgtta ttatcttaaa
    16741 tcaattcata ttttcgtctt ttttaaattt ctaatcctat aaatctccac caagggaatg
    16801 ttatacatat tattataaag taggttaaag gaatcaaagt taaaccatac ttgaaaataa
    16861 ccttgctatt atacagattt tcaccatgac ccaccattat tgtagcatga tgaaatggta
    16921 atatgtattg tatacttact ataatgtaga caaatagaca taaagtaaca ctattttccc
    16981 ttagtatatg caaacttcca agcagtggta ttactacaga tgatgtagta acagcacttc
    17041 caagacatat attcaagatt attgtgagag ttatcaaaaa taatatcgaa ataatttctg
    17101 aagagtttgg tataaatttt atcaaataat ttcccattat atctacaact ccggaatact
    17161 ttaacactcc tccaattgaa aatgctgcta taaaaaaaat aaggaccttc caatttattt
    17221 cttttaaggt gctaaatcca actatttttc ttagtaataa aagaagtaca caaattgaca
    17281 ttataattaa tgtatttatg ttatgtatga actgagttaa aaacataaaa aacattattc
    17341 ctaagcataa gaatacgtat ttttgttctt tgtttagcaa attaagctct tttttaaaat
    17401 tagaatatga aaactgaatc ttattaacct caagattttc atgagaaaca aattttattg
    17461 aatgtaattc ttttttaaag acaaagataa ataaaaaata agttataaaa caagtaatta
    17521 tagttggaac agacatataa aaagcccatt gcccccaatt tatattacaa tttccgagtt
    17581 ctagtacaac atagtttagg agagtgtctc catttacaaa aaacattgat gtaaaggtag
    17641 aggctgtaaa tatactaaat aaaagtatag attttgaatc ctcagttatc tgttgttctt
    17701 ttaaaaactc cttgtaaaaa gcagatacaa gaataaccct cggaaatggt tgtgggataa
    17761 aaaatattaa aagtatacct aaaatatatg ataaaagaat cattttttta ggggtattta
    17821 cagtatttaa aattaacttc tcagaaataa tttttgcgac acctgttttt gtaactgcat
    17881 tagtaattat gtatgcaaga attattatgt aaaaattttc tgtaaataaa aactgtaaaa
    17941 taacctttat tggtgcaata ttaaagataa atgctagaat tacaaaaaac aatgcaacaa
    18001 cagttttttc aactgagtct atagcccata tcaagatagt taaaaaagat aggcatatag
    18061 aaaattttat gttgaaattg taattaagag agaagtagag aattatagta gctataacag
    18121 ttatataaaa ttgttttggc ttaagaataa tacccatttt tatattcacc tccataattt
    18181 attatagcat aatgaaggtg aatacaatga aggtgaatac atgtttataa aaagtttatt
    18241 tattgattct atgatttaca atggctttag ttttccaacg ccctttatta tagtagataa
    18301 ctgtgacaat aagacctaaa gtccaaccaa aaggaatacc catccaaatt ccatttgttc
    18361 caaaaaatct agaaagcata taagaagctg gaagtcttcc aagccataaa gatactattg
    18421 agcttataag ggcaaacata gagtcaccag cacctttcat tgcacttgaa agcacaaaag
    18481 aagtgccaat aaataaaaag aatggtccta ttataaataa gtaagaagag ccaattttaa
    18541 tgacatcttt atcagtattg aatagagcaa ttagattttc tctaaacagc aaaattaaag
    18601 caataactat aactgctaaa actaaggtca tttttataga ttctcgaatg ccttttttga
    18661 ctctttcatt ttctccagca cctatgtttt gagcaacaaa agtagaaaca gcagaaccaa
    18721 ggttcataat aggtaagctt ataaaatttt caattctaag accagcacca aaagccgcca
    18781 tagcagatgt accataacta ttaactaaaa attgaagagc catatttcca attgaaaata
    18841 acatttgttg aactccactt ggaagtccta atctaagccc atctttaaat attttattat
    18901 catatataat tcctttgatt ttaaatttaa gcacttcatg ttttttattt aaatagatta
    18961 tactgattat aaatgatact gcctgagcaa ttatagtggc aagtgcaacg ccctcaacac
    19021 ccatttttag gactacaata aaagttaagt ctaaaactat atttaggatg gtggctatta
    19081 ttagaaaata aagtggagtt attgaatctc caagtcctct aagtattgca cttactgaat
    19141 tatatccagc agaaaataat attccaccaa atattatagt aagatacaat tttgattgag
    19201 aaaaaacgga ttctggtgta ttcataagcc taagcatggg tccaccaaat actattccaa
    19261 gaatacttat taatatagaa ccaataaata aaagtatata tgtggtatca atagtagctt
    19321 ttactttttt taaatctcct gacccataaa attgtgatac taaaatagaa aatccaaggc
    19381 taacacccat aagtgctgcc accaataaaa acattatagg gttagctcca gagactgccg
    19441 ccattgcctc ttttccaata aatctaccaa ctattatact gtcagctgta ttgtatagtt
    19501 gttgaaataa actaccaata agcatgggca tggcaaaaaa gaatatggat tttccctcat
    19561 gacctgtagt taaatctttc accttattcc tccaaataaa aaaattatta atttattata
    19621 gtataatctt aacataaact ttatatccaa actataaata aattgtatca aaatatcata
    19681 tattttttta aaatgtaaag aatatagtta taatttgaat ttaataaatt aatatttaat
    19741 ataatcgaat attaatacaa aatcaacaca atatatacgt atatattgac aaaattaatt
    19801 atataaatta aaataatatt cgtaaagaaa aaatcatgtt ttatactgta taacatataa
    19861 ttttgacaat atgggtcata agtttctacc ggaataccgt aaatattctg actatgtata
    19921 ctattattta gttaattaaa tatttaatta actgaattat gaaggatacg gctcagctta
    19981 tcaactactg tgtcgttttt ttgtaaaatt taataggagg tgttgttatg caaacaacaa
    20041 acagtagtac tatgcagaaa ctttttccaa ttttgactaa taaaaatgtc gacatgaaga
    20101 aggaagtaat tgcaggagta actacttttt taactatggc ttatataata gctgtaaatc
    20161 caaatatttt atctgaaaca ggaatgcctg caggtgcact tgttacaggt acttgtttag
    20221 cagcagcatt tggatgtatt ttaatgggtg tagttgctaa tcttcctttt gccttagcat
    20281 caggtatggg tcttaatgca ttttttgcat atacagtagt tttacaaatg ggtgttcctt
    20341 gggaagtagc tcttacagca gtgtttgtag aaggtattat ttttatagta ttatcagtaa
    20401 gtggagttcg tgaagctgtt gtaaatgcga taccaaaaaa tatgaaatta gctgttacag
    20461 gtggtatagg aatatttatt gcacttatag gtctagttaa cagtggaatt gttattggag
    20521 accaagccac acttatcaaa atgggtagat ttacaccagc agtaataata acttgtatag
    20581 gattaataat tattgctgta ttagataaaa aaagagttaa aggttctata ctttttggaa
    20641 tagtagtgag ttcattactt gcttgggctt ttgcttttat gaatccagag catgcacaaa
    20701 aattaggaat atatttacct ggtggattat ttaaattcga aagtttagca ccaatagcag
    20761 gtaaaataga tttaggatat gtactacatc cgaaaaatat aggtggtttt ttagtagtag
    20821 tttgtacatt tttatttgtt gatttctttg atacagtagg tacattagtt ggtgtttgtt
    20881 ctaaagcaaa tatgttagat gaaaaaggga atgttcctaa tgtaggtaga gctttactta
    20941 cagatgcagt tgcaactaca gttggtgcag gacttggagt atccacagtt acaacttatg
    21001 ttgagagttc aacaggagtt attgcaggtg gaagaactgg atggacagca ataacagttg
    21061 gaattttatt cttagctgca atgtttttct ctcctgtatt tatagcaatt ccatcatgtg
    21121 ctacagcacc agctttaata tatgttggat acttaatgct tggtacagtt aaagatatag
    21181 agtttgataa tataactgaa ggtgttccag cttttgttac tattgcttgt atggcattaa
    21241 catatagtat aggtgatggt ttaactttag gtatattaac ttatgttttc gtaaatatat
    21301 tttataatat atttggagct aaaaaggcag aagacaaaaa acatgtttct atagtaatga
    21361 ttgttctggc aatattattt ataataaaac tttggctatt ataatagata ttatttaaaa
    21421 ttttaattta atataaaata aatagctgta atttctcatc aattttgatg gaaaattaca
    21481 gctatttcgt atttatttca ttttattatt taataatatc tactagctct ccattttgta
    21541 aagttttagg tgtaattact atattgaact ctttttgcaa atcttttata atatccaatt
    21601 ctttttttgt tattattgag attgtgttac catttctatt tcctctagca gttcgaccac
    21661 atctatgcag atattcgttt ttactttttg gaaaatctaa gttaaaaaca tgacttacat
    21721 ccactatgtc tagtccacga gcagataaat cagttgtaat taaaatcttt gctttaccaa
    21781 gtttaaattt atttattgca ttctttctat cttcttttgc catatttcca aaaattccta
    21841 ttgctttgta attatgataa tttaattttg atactagaac ttctatattt ttttcattat
    21901 ttacaaatac gatagctctc tttggatttg tggctgttaa tgtttttcta agaaaagtga
    21961 acttatctct tatttcacct aacaaatatg agtgattgat gtttggattt atttgtgatt
    22021 tttcctttgt ttttattatt tcaaactctt tcataagttt atcacaaatt tttatagtgc
    22081 tgtcagtaag acttgcagag catcctataa tttgtctatc tcttaatgtt gttcttatta
    22141 tgtcttctat acaagttata ttttttccat tcaatagatt gtccacttca tctaagacaa
    22201 tagtttttat attgtgtgat tttaactttt tttgttttat caagtctaaa actcttccac
    22261 aagagccaat tactatgtgt ggttttactg attttatatt ttttatttgt ttttgtatat
    22321 ttacttctcc aattaaagct agagaagtaa cagagatttc cgcattttta gccaataatt
    22381 caacttgatt tgtaatctgc attactaatt catgcgtagg tgcaagtata agagcttgtg
    22441 tttctctttt tgatgtatca attttttcaa atataggtaa aaggtatgct agtgtttttc
    22501 ctgttccagt ctgtgaatta atcaataaat ccttattttg aattatattc cctataacaa
    22561 gtgactgaac ttctgttgga gaagttatgt cttgtttttt aagtccatct attagagtgg
    22621 aacttatttt tagttgttca aatgtattca tattttgctc cttatattta ataattatag
    22681 tcaactattt tttattatac attgtttagg caaatcgaac tatatattct tttataatta
    22741 tgtgtaattt gaaagtaaat ataaattata tttataccct tataattatg ataactttgt
    22801 attttataaa tttttaaaat aaacaaataa aagttgtaat tgtttgatgt ttgttatata
    22861 ttatatataa caaatatcaa aactataata tggagggaaa ttatgttaaa agtaatcaat
    22921 ttatctaaat catataaaaa taaaaaagta gtaaatagtg tctcatttga tgtaaatgat
    22981 ggagagcttt ttgggtttat aggacataat ggagcaggta aaactactac tattaaagca
    23041 attgttggaa tacatgattt tgaaaatgga gaggtactaa taaattctaa atctataaaa
    23101 aaacagcctg ttgaatgtaa aaaggaaatg gcatatatac ctgataatcc agatttatac
    23161 gaatcattaa ctggtataca ataccttaat tttatagctg acatatttga agttgccaaa
    23221 gataaaagag aagagttaat aaaatattat tcaaataagt ttgaactcaa taaagcatta
    23281 ggtgatttaa tatcttcata ttcgcatggt atgaaacaaa aattagctat aatttcggcc
    23341 ttgatacata gccctaaaat tttaattctt gatgaacctt ttgtaggtct tgacccaaaa
    23401 gcttccttta tattgaagga aattatgagg gagttttgtg ataaaggtgg ttgcatattt
    23461 ttctcaacac acgttttaga agttgctgaa aaaatttgtg ataagattgc tataataaaa
    23521 gatggaaata taattgctta tgggactaca gaagaagtta aaggaagtaa ttcacttgaa
    23581 agtattttca tggaattaat agaaaaataa aatgtttttt atacaatata gtatctaaag
    23641 tgaggaatga taaaatatga gcaatctaag tatattaata aaaactaata taataaatga
    23701 atttaaatta aatgcattaa aaaaatctga tggtagagaa aaacaaaaaa taatgggaat
    23761 gatactttca gctattatca taacagggtt attaattttt tatgtaacca ctttaagtct
    23821 ttccttagtt gatattttaa agcaaataaa ccagatggaa atgctactga tatttggatt
    23881 tggattgtca acattaacaa ctatcgttac atcattatat aaaacgtcat catatctttt
    23941 tcaagcaaaa gatttagaca ttttgactag tttacctata aaagaatcta ctgtactagc
    24001 aagtaagata ttaatgttgg tgggagcaaa ctatttattt tcttcaatct gtatgattat
    24061 accagcagtg gtttactttt taaattctga tgtaagtata acgtatttcc cttatttgat
    24121 attgctattt ttagctttac cattattacc aatagttgct tcatcaataa tttttatgtt
    24181 tataggacag atatcatcaa gaataaaata taaaaattta gtattaatta taggtagtat
    24241 tatattgatg ttgctttata ctctacttat gtcaagactt aactctatgt cagttgaaat
    24301 gttaaagaat agtgtatcta tttcagagac gattaggaaa atatatccac ctatatatta
    24361 ttttgttgat gctcttaaaa caggaagtgt agtttccttt ttagcattta tagcaatttc
    24421 aataatacca ttttttatgt ttgtaacttt atttgcaaaa aaatttaaaa atataaatgc
    24481 taagatgagt gaaggatata agtcaaaaac ttacaaattt aagagtcaaa aaacttcaag
    24541 accttcaaaa gctctattaa aaaaagaatt taagagatat acttcttcat ttatatattt
    24601 tttaaattca tctgcaagtt tgttatttct aatagtaggt gcaattctaa tattgttatt
    24661 tggagcagat aaaatgggtg agttgctgaa attgaatata gattttaatt ttataaaaat
    24721 acaattattg ggagtattct tctttataat agtaatgaat tgtacaacat actgttcaat
    24781 ttctcttgaa ggagaaaatt tatggatact gaaatcttct ccaatagatg aaagagaaat
    24841 attctggtca aagatattga tgaatttttt attgaatgca ccattatcta ttttatgttt
    24901 aatattagta tctataagat tagactttga aattcagttt attattgtat caatttgttt
    24961 gattgtaagt ttttcaatgt ttgtagcatt gatgggatta ttatcaaatt tactatatcc
    25021 aaaccttgat tggaaaaatg aagtagctgt agtaaaaaga agtgcaagta tggtaattac
    25081 aatgttagta tcattagctt atgttgttat acttggaggt atatatacat tacttggaat
    25141 ttcgttttta aatatatata ttattttggc aagtatgctt accttgatat tagattttat
    25201 gatatggaga attatttcta ctaaaggagt aaaaatattt aaaaatctat aggtgtagtt
    25261 atgtcaaata aagacttatc ttttttagtc ttgcaaataa taggttaagt agtatattat
    25321 gtatagtgat atgaaaaaat ttaggagaaa ataaatgaga aaattatcca aaaaagaaaa
    25381 agattttatt caatatggat ttttattatt tttgatatgt attactactt atttagtatt
    25441 aactacttta gatataaaaa tgatacctaa aattataaga ctagtaaata agacttatat
    25501 atttcttgga atattgataa ttataatata tatgataatt gaatctattg taactcattt
    25561 gataataaat gcagttcaaa aaacaaaagt gaaattcatt ggtattaaaa tggctacaat
    25621 gggattttat tataacttag ttactccatt tgcatctggg agtcaaccaa tgcaaatata
    25681 tgcacttaca aaatatgatg ttagtcttag taaatcagtg gctatagtta ctaataaaac
    25741 agtagtattt caaagcacag ttaccgtatt ttgtggaatt ttaattttgt taaataagtc
    25801 attactgata gagcaagtac attctgtgaa agtcttgata acttttggaa tgattatgaa
    25861 tgtaagtatg ttgttaggtg gactactaat agtatttagt ccaaaacaag taaaaatgat
    25921 agcagaagtt ttgattaatt ttttatctaa atttaaaacc tttaaatttt tagattcaaa
    25981 acgtgataga ataaatcatt atattgatga ttataattat tctataaaaa tgtttattaa
    26041 aaatgtaaga atcttagttt taagtatatt acttactgtt ttacaattaa tcgcatactt
    26101 cagcatagtt tattgtgtgt ataaagcttc aaatttaaga ggagtctcat atatacatat
    26161 aatgacacta caggtctttt tatatatggc tatatcgcca attccaaccc caggaaatgt
    26221 tggagctaat gaggttacct tttttactat gttttctagt ataattccaa aagaattatt
    26281 ggggtactcc gtgctcttat atagtgggtt tgtgtactat tttatattaa tagtttcagg
    26341 tatatttaca tttggaacgc attacacatt aaattcttgg aaaaaggaaa ctaaagtaaa
    26401 ttctaattta gataaggtta ttgaaaaatt aaattaataa aataattagg gaaattctat
    26461 atataaatat ggtgttagat aagctatatt atattgagat atttcccttt tttgattaaa
    26521 attatagaaa tttgaaataa taagtaataa acagaacgat tgatattgtt ttgaaaggag
    26581 aagttatgaa acaagataaa aaaaatgaaa aacaaagtga gatttctaag ataaaacaaa
    26641 gtaatgataa taaacttgaa gtagctcaag aattacatgt aagtaaaaat ataggaaata
    26701 tgcttggata tagaatagat aagaaaaaaa tgaatagacc aagttaatga aaatgttgaa
    26761 aatagtacat tttaaaaaaa atatataatg aaatgtttta ttgttaaatt taaacttatt
    26821 ttaataaggg aaaaagtcga aaaatatcta aaaagatatg gatataaaaa atattaatat
    26881 atatagacta taaacttgac aaaatcaacc ttttaatgaa tagcaaaaaa tggaaaaatt
    26941 atataagcgt tatttaatta tcaaaaatga aagctaaatt gcatgtgcta aaaaaaatga
    27001 ttgataacat ttatttgtgt gctataatta tatagtaaaa cgaataagta tattgcataa
    27061 tgtatgcaaa ttgggaggag agacagacat ggaagcatct atacacacaa ttgccagcaa
    27121 taatttattg ataatttttg ctattgtaag tataactgga ataatttgta gtaaacttag
    27181 tgaaataata aaagttccag atgtagtgtt atatttactt gtaggtattt taataggacc
    27241 atcattttta aaatttatag atattcgtgg atttcaaata gaaaatcaac taatacttac
    27301 ttttggttct gcatttattt tatatttagg tggaaaagaa ataagtttaa aagtattgag
    27361 aaatgtgaag atatctgtat tcttattagc tactttagga gttgtgatat ctgcttttat
    27421 aatgcagcaa gtgataggat ttacttttgg gataagtgca atgactgctt tattagcagg
    27481 aactataata gcatcaacag acccagctac tcttgtacct atatttaatc aggtaaagat
    27541 aaaggataga gtaaagcaaa ctgtaataag tgaatcagct tttaatgatg caacaggagc
    27601 tatactaaca tcagcagtgt tggctgtaat tttgtcaaat aaattttcct taggtgaaaa
    27661 tatttatgaa ttggggacaa tggttattgt cggagtttta gttggtttaa ttacaggaat
    27721 actgcttttg aaattagtta atgataaacc ttatggaata tttaaagatt ttgcaccaat
    27781 aatatctgtt atttcagttg tagttgcata tgaattatct acaaaattag gtggaagtgg
    27841 atatatgtct tgttttattg taggtataat aactggtaat aagaaaaact ttaaaatttg
    27901 gttaagtcaa aaatcttatg atgcagattt ttatgttgct gaaactttag gtactatttg
    27961 tcgtatggca atatttataa tactgggtag ccaagttaat ttagctcagt taagtaaata
    28021 ttttatgccc tctgtaatta cggtattagt attaatgttt atagcaagac cactttgcgt
    28081 tttagtttgt acacttgtag atagagaagc aaaatggagt aaaagtgaaa tattatttat
    28141 gatgtgggta agggaaacag gcgtaatacc agcagcactt tgtggtatta tttcagcaat
    28201 gaaagttcct ggatacgaag taatttcatc tgtagtattt atgaccatac taattacctt
    28261 agtaatacaa ggaagtacta caaaattagt agctaaaaaa cttggattat tagaagaaga
    28321 agttataaat ataagtgaaa aagtatcaac tttttaaagt tttgatttaa ataataccta
    28381 ttaatggcta ttttaatatt gtctaatgat gattattgaa atagtcattt ttttatgtat
    28441 aagcaattta cagaatttac atattagaca tatttattat caaaatttgt tgaagctatg
    28501 atataattag ttgtatttaa aataagaata gcaaataagg gaggaaattt atgtttacgg
    28561 ttatggatat tgtacagcca gatacagtag aagaagcgta ctcaatttta aataaaagaa
    28621 aaactaacca agtaattggt ggaagtgctt ttttaagaat ggggaaaaaa agaataggaa
    28681 caggaataga attatctaac ttaaatttag attatataaa agaagatgaa gattgtgttg
    28741 agattggttc tatgactact tttagaacat tagaaacaag ttccataata aaaaataatt
    28801 ttggaagaat aatagaagat tcagtaaaaa atataatagg agttcagttt agaaatgtag
    28861 taacagttgg tgcaacagtg ttttctaaat atggtttttc tgacttgata gtagcattac
    28921 tttcattaga tacagaagta gaattatata atattggaag aattagtctt gaagagtttc
    28981 taaataggga ttatgagaaa gatttactta ttaagatata cataaagaag acaaataaaa
    29041 atgcttctta taaatcactt agaaatgcaa agagtgatta tccaatctta aatgtatctg
    29101 tatcaaaaca tatgaaacaa tttaagttat gtgtaggagc aagacctcag aaagctacga
    29161 ttgcaaaaca agctagtgaa tttctatcta ataatgaaat caatgaaatt aatatagata
    29221 aagcagtaga aatagcatca gaagaattaa cttttggttc taacatgaga gcatctaggg
    29281 attatagaaa agctatgagt aaagtacttt taaaaagagc tataatggag gttatttaat
    29341 gttagtgaag attaatataa atgggaagaa aaaaagtgtt gatatagaac cagaagaata
    29401 tctggttgat actttaagaa aagctggtaa tttaagtgta aaaagaggtt gtgacacagg
    29461 ctgttgtggt ctctgtacag ttttaattga caagaaacct acattatctt gtgcaacact
    29521 gacattgaga gttttagata gagaaataac tacaattgaa ggtttagaaa atgaagttaa
    29581 agaatttagt gaagttttgg taaaagaggg agctgagcaa tgtggtttct gttctcctgg
    29641 ttttatactt actgtaattg caatgaagga tgaacttgaa aatcctacag atgaagaaat
    29701 aaagcattat cttacaggaa atctatgcag atgcacaggg tatatgggac agttaagagc
    29761 tatcaaaact tatctggagg taaaatagag tatgaatata gttggaaaag gaatcaagaa
    29821 aatagatgga atgagtatca caacaggaaa gcctgtatat acagatgatt tatcagcaaa
    29881 agatgctttg gtagtaaaga tacttagaag tcctcacgct tatgcaaaaa taaaagatat
    29941 agatacatca aaggcagaaa tggttgatgg tgttgaatgt gttttaacat ataaagatgt
    30001 accaaaatct agatttacac ttgctggtca gacatatcca gagccatctc catatgacag
    30061 attaattctt gaagatgttg tgagatatgt aggtgatgaa gtagctatag tggcagctgt
    30121 agatgaaaaa actgcaatta aagcaatgaa tcttattaaa gtaaagtatg aagtactcac
    30181 acctgttttg gattttgaag aggcaatagg gaataacact gtagtacatg atgaagatag
    30241 acattgtaat tttgatatag gtatgcaaag agaaaaaaat atagtatcac atcatgatta
    30301 tacaaaaggt gatgtggaaa aagtattaag taattgtgat atagtgattg aagaaactta
    30361 ttatactcaa gctcaagcac atgcaatgat ggaaacgtat agagcatata attatttaga
    30421 ccatactgga agattggttg tagtaagttc aactcaaata ccatttcatg taaaaagaca
    30481 tttatctcgt gcactagaac taccatctag taaaattagg gttataaaac ctagaattgg
    30541 tggaggattt ggtggtaaac aaactgcatg tgttgagatt ttttctgcaa ttgttacttt
    30601 aaaaacaggg aaaccagcta aaataattta tgatagaaaa gaaactttta attgttcaac
    30661 aagtagacat gcaatgagat taaaagttag actaggtgct acaaatgatg ggataataaa
    30721 ggcaatagat ataaaagcac tttctgatac tggagcatat ggagagcatg cttctacaac
    30781 tattggtttg gttggagaaa aaactttacc aatgtataat aaagttgaag caacaagatt
    30841 tattgcagat gtagtatata ctaataagat gccagcagga gcacttagag ggtatggagc
    30901 atcacaaggg tgttttgctg ttgaatcaac tataaatatg cttgctaata aattaaaaat
    30961 agacccaaca gatttaaggt taaaaaacgt ggtaacagaa ggtgaaacta catttgcata
    31021 tgggaaaact ttaaatagtg tcgacttaat aaaatgtata aataaaggca aagaacttat
    31081 tggatggaat gaaaaatatc cttgcaaata tcttgataat ggaaaagtta gaagtgtagg
    31141 tatggcaatt actatgcaag gttctggtat acaaggtctt gataagtctt cagctgaaat
    31201 aaaattgaat gactgtggag attatactct tatgataggt tctactgata tgggtacagg
    31261 aagtgataca attttagctc aaatggctgc tgaggttctt gagacgagta ttgaaaatat
    31321 aacagttata tcagctgata ctgacttagt tccatatgac ccaggttcat atgcttcaag
    31381 tactacttat gtaacaggta tggcagtagt taaggcagct caagatttaa gagaaaaaat
    31441 aatttctgct ggagcaaata aactaggtgt tgataaggat gaagtagaat ttgatggtat
    31501 aaaattaact agtaaaaaag gtagtacttt attatttgat atagcagtgg attctacaat
    31561 tggtccagat actaatcaat taataggtct tgcttctcat ggtagccctg tatctccacc
    31621 accttttata gcaggttttg cagaaactga aattgacaaa gaaactggta aagttgattt
    31681 agtaaattat gtagctgtag tagattgcgg aacagttata aataaaaatc tagctaagat
    31741 acaagttgaa ggtggaattg ttcaagggat tggaatggca ttatttgaag aagttagata
    31801 cacagaaaaa ggacacatgg atacaaatac atttatgcaa tacaagattc cagctagatg
    31861 cgatattgga aatgttaaag tagattttgt tgaaacttat gaaccaactg ggccatttgg
    31921 tgctaaatct gttggagaag ttgttataaa tacaccttta ccagcaatac aagaagctgt
    31981 gtttaatgga attggtgtaa gaataaatac acttcctatt acacctgaaa aagtttttat
    32041 ggcaatgaat aaataattat ttatgaaatt ttagactagt tttacatgtt aaacaaccag
    32101 ttatgtcata cctgttgaaa gatatttaat aagtagttat tataatattg tgaattttac
    32161 ttataaaata caaaattaaa taaggggatg atgttttggc tggaaatcta aataatatga
    32221 gagcagtaaa taattttaga ggagataaga acattttaga atgtttagtc agctttgagg
    32281 gtcgttcaat aagtcagaga aaagcaaagg tattttttaa agaaaaacaa aatcaaatag
    32341 aaattgattt tgtggaagaa gaaatttcta aattgattga aaatgttgtt ttgaatacat
    32401 catatcagga aatgttatat gatgaaatag aaaaacaact ggaaattgat tgtataggta
    32461 cttggatgat attatctaaa ttgaaagatg gtagagttca ttgattttaa aataaattat
    32521 tagagcctaa ttttaaggct cttttttact gcttttaatt aacaacagaa aatctatatt
    32581 taatttacat ataattttaa tatcatatat tctatatata taaaattgag tttgtatgta
    32641 ttatattgta taatataaat tgaattagtg aaatagttcg ttaaaataat ttgtttgtat
    32701 aaaatcattg tttaagttta tagattttgt ataaaataaa gttatgttat taattttttt
    32761 agaagtaaaa tttttactag gagacagata tgagaaaaaa taatattaat atagcattaa
    32821 cctcagcaat tacagcaatc tatgcagttt taacattatc attgggattt ataagttatg
    32881 gaccaataca atttagggta gcagagatta tgatgctttt ggcattttta gataaaggat
    32941 atatagtagg tcttacatta ggttgttttt tagcaaatgt aatagggcca tatggtgtgc
    33001 ctgatataat ttttggaaca ttagccacat ttataagtgc aagtatgatt tatattacta
    33061 gaaagttagg taagcaaaat aaaagtactt taattatagc ttctttatgg ccgactatca
    33121 taaattcgat tgtggttggg ctaatgttaa atatattctt tggacttccg ttaattttat
    33181 ctatgataca ggtaggtttt ggagagtttg tagtagtaac aattgtagga gtaccatttt
    33241 tttgtttttt aatgaaaaaa tataaaaata ttatcaatat taaattttaa atagtgtata
    33301 gtaatttaat tgagagtatt attggtgaaa agaggtgttt atttgtcaaa aataaaaaga
    33361 ttgactgatg tttggacata tattaatgat aagcaaaagt ttacaataaa agaattatca
    33421 gaggaattta atctttcagc taaaacaata caacgatatt taaaagaatt aaataaaatg
    33481 ggacttccaa ttcaagcaga acaaggtaga aatggtggtt atagggtgct aaataatagc
    33541 tatatacctc ctgttatatt tacagaaaaa gaagttatgg ctatgctatt tgcacttaag
    33601 tcacttcagg tttataatta taagtcaatt gagatagaaa ttaattctat aatgagaaaa
    33661 gtaagttatg agcgtaagag tagtataaaa gtaggtatag aaaatattaa aagatatatt
    33721 ggatttgtag ctaataattc taatgatgga gagtttaaga gtattaatgt aactgagttt
    33781 tttagagctt cttcagagtc tctaatttta aatattaagt ataagtttgg taatcagatt
    33841 ttggaaaaaa aaatatgtcc tataggtata tatttaaata aaggagcatg gttttcacca
    33901 gcctacgatt gtaaaattga taaaataata ttagttcata tagataatgt aattgacata
    33961 aaaagaacag gagaaagtaa aaaaatacat ataaacttgg aagagtggct agatgaagta
    34021 tataacaatt tatatgaaaa taggtcaacc actaaaaaaa ttggtgaaac gatttatcta
    34081 aatgtattat taactaaaga aggtgtttct aaaataaagg acagttctta taatttagat
    34141 atggaactaa atgaggatgg tagtggaaca attagtacat ttataagggt tgaagatgta
    34201 gattactatg cttctatttt atttttaatt ggaaataatg ctaaagttat agaaccaaaa
    34261 tttctgaata agctacttta tgacaaggcc aatgagttaa gatattttta tgaagaaaat
    34321 atggtataat atttagaaat gttgaaatta aataattatt aaggagatat acattataat
    34381 ggaaaatttt aataagaatg ctaaaataat tggtattgga gctgaaggta tcaatataat
    34441 aaatgaaata gaagaaaaaa taaaagccaa tatggatata gaaaaaataa acataaatca
    34501 agagattgaa aaagaatacg ttagaagtct tctagatggt gtagatatat tatttttaat
    34561 atattcatct gaagataaac atattaaaga gattataaaa gctatttcat atatgtcaaa
    34621 tgagagaaga gttctatcta taggaatgga ttgttcagag aaagaaaata aagaagcttt
    34681 agagcttgga agagaattta aaatcaataa cgatagtata tttaaatttg ttaatttaat
    34741 gaatatcatg gtagagtcta tttctgattc ttgcatgata aatatagata ttactgattt
    34801 aaaagaagct attgtaggag ataaaggaat taagtattct tttgaagagt ttgaagatac
    34861 aaaggaatat agcgagatgg ctgacatttt atttgacaga atggaatata ttggtgagga
    34921 atttataagc aagaaaggaa ttgtatttgt tgaaggaagc tcggaatttt ctataatgga
    34981 acttaatgat ttaataaata atattcagag aaagatagaa gaaagttatg aagtaatatt
    35041 ttctttatat atgaaggaaa atctagatgg aaatattaga ataggtttat tgtataatta
    35101 gtatatttta gatattaagg agagtgtata tgtctgaaaa tataagagtt acagagtact
    35161 ggctaatgga agaatttttt tatcaggaaa cagacacacc acagattttt agagaagaaa
    35221 gtataattgc acttggattt gatataaaaa taaatttaaa aaaagtattt ggtatgggaa
    35281 aaaaatcaga aaagtatatt aatgagaatt gtaatgataa agattttata aaaagatttg
    35341 tgtcaattaa aaaaggagat tattttttat ataaggcata tcaaaatata gaagaaaaag
    35401 ttaaatgtaa tgtgtctatt ggcatggttg aagaagattt tgaaaatgga tatgaattaa
    35461 gtcatatttt agggcataca ctaccagtaa aatggatgta taattttgat acagtttcaa
    35521 attgtaaagt atatacaagt gaattttata aattaaataa taatgatatt agctcatatt
    35581 tagaaattat taattcacaa gataagaaat cattgagaaa aagaatagaa gaaagtgaaa
    35641 ataataaatg gtatttaaaa aactattatt ataaaaatgt agataaatgt gtaaatgatg
    35701 aagaactatt tattcagcct actaatctag aacagttaga aaatataaaa aatataaaaa
    35761 cagatgatta cattttattg tataatagcg agaaagtaat ctgtgaaaat gaccatacaa
    35821 tgaagagtct atttggtgta tgtcaagtca tggaaggatt cgataaagag aaagtaagta
    35881 ctttggagga tggatatttt ttccctgtta gatggataga gtatgaaaag gaaaatatag
    35941 atggaaatgc atgggttata tttgaaaata atagcatggt tgaaaagtat gtaaaaagat
    36001 ttactaataa aataccatta aatactatac tttatggacc accaggaact ggtaaaacat
    36061 acaatacaaa acagatggtt tataatctag taaataaaac tagtttaaga aacaggtact
    36121 atacaggtta cttagattat aaaaataatg tagaattttg cacatttcat caatcatatg
    36181 gatatgagga atttatagag ggtcttaagt ctgatggaga aggcaacttt aaaccagaag
    36241 atggaatatt aaaggatata tctatagaag catgttatga tgcattgaaa tttgaaaaaa
    36301 agatgagttt tgagttagaa aaagatagct tgactttaga agctataaaa aagagaaaaa
    36361 agaagttagt attagaaaat atagaatata gtgatagttt taattttgaa gaatcagaaa
    36421 attatgtttt aataatagat gaaattaata gagggaatgt gtctaaaata tttggtgaac
    36481 taataacatt attggaagat gataaaagac ttactaaatc aaatcagact attgtcaaac
    36541 taccatattc aaaagaaaaa ttttttctac ctcccaattt gtatatagtt ggaaccatga
    36601 acacatcaga taaatcaata gcacttttag atatagcttt aagaagaagg tttaattttg
    36661 aagaaattat gccaaattat gatttattgt ctattataga tggcatagat attagaaaaa
    36721 tgctatatac aatcaataaa aggatagagt ttttgtatga tagagaccat gttattggac
    36781 aagcctatct acttgctgtg gaaaatatta atgatatagt agtagtattt agaagtaaaa
    36841 taataccact tcttcaagag tatttttatt atgattcaga aaaagttggt ttgattttag
    36901 gaggaattgg aagaaatgaa aaagataaat acattgttta taaagaagaa cttatagctt
    36961 ctgagttatt taaaaataat aatgcctcaa taatggagag taaagttaac tattgtataa
    37021 aacaaaacat atctagtgag gagttaaaaa atatatatga gtaaaaatat atatgttaag
    37081 gaaacttatg aatggataag agtaggtaat ggtgaaaatg agcttacaga aattgaatat
    37141 gaaaaattgc ttaaatatct agagaacaat aatgatgtat taaaaagtaa tataatagat
    37201 attaaataca aaaaacttag atttataaac tatgtaggta ttatatgttt tgaaaatata
    37261 atacttgaaa tacttcctaa gttgtcatta agtgataatc ttgtaaaaga tagagagata
    37321 ctattacaga tgctttccat atgtaataaa attccaatta taatgaatga aaaaataaga
    37381 ttaagtttaa aaaattataa tctcctaaat ttttttatta tgtatttcat tgagagtatg
    37441 caaatacaga tgaagaaagg tatttatttt gaatatataa ataaaataga gaacttaaat
    37501 gttataaggg gtaaaatatt attaagtaca tatgcaaaag aaaaatgtat ttctccaatg
    37561 aaaataagat gtgaatatga tgaatatagt gaaaataatt tcttgaatca agttcttaaa
    37621 aaagcatgta tatctatttt atgtagaata aatgacaatt caattcaagg aaagattaaa
    37681 aaaattttaa actattttca aaatgtagat ttaatttata tagatagaaa aaaactatta
    37741 gattataaat tttgtaaaaa caatgataga tttagagatt gttatttact agctagactt
    37801 ctacttttaa atttgtctat ggataatagt caagataatg aagaggcatt ttctatatta
    37861 tttgaaataa atactttgta tgaagaatat ataggaattt taatcaaaag tatatgggat
    37921 aattcattta gagaaacata tatacaagat aagagtaaat ttcttttgaa aaatgaacaa
    37981 acaggtaaga aaaactttaa tttaagacca gatatagttt tatatgattt gaaaagtgaa
    38041 tatgaaatta taattgatac taaatggaaa gctattgaag tagattcaaa tgttttttat
    38101 aggtcaagtg atatatacca gatgtatgca tatataacaa catatgaaaa tgcaaaaaga
    38161 tgtatattat tatatccttg tattcaaaaa gataaaaatt atagttcttg gaaattatca
    38221 gaatcattta agggtaagtt tatagaagca aaaactgtga gattagatga tataaaaaac
    38281 acaaaaaatg atttaaaaaa gataattttt aattataaat tttaaaaata ag
//
LOCUS       DAMKOJ010000035        37490 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000035 DAMKOJ010000000
VERSION     DAMKOJ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37490
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.037"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            480..4028
                     /locus_tag="PC592_001892"
     CDS             480..4028
                     /locus_tag="PC592_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4055867.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAIFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDKMVIDLMDSNVKRSSLMRM
                     TISTLDGECYSNDGIIRNVQDRDYFKKAKNGERNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVANKNGAIIAQKTNKNSKTLSCIFQL
                     FNKNNCDEVYCLKTIKENMKNDKSGYFNYDLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYVFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSDEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVKKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLKDELNNKLIKLIFK
                     DDRIGLINSINKQLKLSDTFASEQRVEKREGTIIWILLKGRKIIYENGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSEGSEYEEREIRLRTRDTTYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIASDLVNLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRKYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKIDKVKYIINTRSTEDIDNVEKSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNLVCKNTFEWCNEGITSEINNLKNIYYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGSEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLGMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQNKPCKKCPMIYLKDGDDTYKSFMRNKKF
                     EIQANITTTTLKWFDGKDACLIFGSEVTSIESEENT"
     gene            4213..6147
                     /locus_tag="PC592_001893"
     CDS             4213..6147
                     /locus_tag="PC592_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDF4055868.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLENAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHRDKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLNREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACNKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKSEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRINKNQQKSSTRKKKKH"
     gene            6253..7248
                     /locus_tag="PC592_001894"
     CDS             6253..7248
                     /locus_tag="PC592_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4055869.1"
                     /translation="MKKYISIILLVVMAMVVLVGCSPGKDNSQNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKDGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     DYSDINFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7220..8005
                     /locus_tag="PC592_001895"
     CDS             7220..8005
                     /locus_tag="PC592_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF4055870.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIILNSSFYIDILYSIGRCFFSFLLAMFFAIILSIVSYLNRFFRN
                     LLKPINALARSIPTMILVVLALIWFEKDSTPFIVGFAIVFPILYDNVLGAILNIDKSL
                     LEMASVYKIRFIDKVLKIYLPVIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7993..8691
                     /locus_tag="PC592_001896"
     CDS             7993..8691
                     /locus_tag="PC592_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055871.1"
                     /translation="MEKIRLSIENINKRYDNRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNKVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTKLNKICDEYLELVGISEYKKFYPQMLSGGLRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFKNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSNELEKNEVLKLI"
     gene            8814..9287
                     /gene="ybaK"
                     /locus_tag="PC592_001897"
     CDS             8814..9287
                     /gene="ybaK"
                     /locus_tag="PC592_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDF4055872.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKFTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9484..10323
                     /locus_tag="PC592_001898"
     CDS             9484..10323
                     /locus_tag="PC592_001898"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HDF4055873.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLGCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEVGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTSINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10336..10884
                     /locus_tag="PC592_001899"
     CDS             10336..10884
                     /locus_tag="PC592_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HDF4055874.1"
                     /translation="MIKITTPVSEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10950..12131
                     /locus_tag="PC592_001900"
     CDS             10950..12131
                     /locus_tag="PC592_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HDF4055875.1"
                     /translation="MSKDYAKLALEMHEINKGKISVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAVINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALESSVENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12426..12812
                     /locus_tag="PC592_001901"
     CDS             12426..12812
                     /locus_tag="PC592_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4055876.1"
                     /translation="MEYKVNDQELNASMFVPFVNRIWPGDYDMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEAFYEKNGCQRSLQSYIIKKKDSY"
     gene            12962..13225
                     /locus_tag="PC592_001902"
     CDS             12962..13225
                     /locus_tag="PC592_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF4055877.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13746..14429
                     /locus_tag="PC592_001903"
     CDS             13746..14429
                     /locus_tag="PC592_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055878.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGEFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            14440..15681
                     /locus_tag="PC592_001904"
     CDS             14440..15681
                     /locus_tag="PC592_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055879.1"
                     /translation="MKIFSNKDIKMFFLILISILVMFIIVGQIVLISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVVHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFIPYMYFFRQQSKIEEASYKIDSFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIVLNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISIKGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSTFTISFLKLTNM"
     gene            15753..16436
                     /locus_tag="PC592_001905"
     CDS             15753..16436
                     /locus_tag="PC592_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055880.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            16433..18763
                     /locus_tag="PC592_001906"
     CDS             16433..18763
                     /locus_tag="PC592_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF4055881.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDSGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANTGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KQEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNGNAEKELEVGG
                     ILSSIPFEVKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTSGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAVSGCLLGSILGLMLHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPVKKICELDIIDSINAQ"
     gene            complement(18944..19786)
                     /locus_tag="PC592_001907"
     CDS             complement(18944..19786)
                     /locus_tag="PC592_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF4055882.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVARLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            20082..20816
                     /locus_tag="PC592_001908"
     CDS             20082..20816
                     /locus_tag="PC592_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4055883.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGNPIEYTISIFRTDKYQYEIVLSE"
     gene            20826..21959
                     /gene="nagA"
                     /locus_tag="PC592_001909"
     CDS             20826..21959
                     /gene="nagA"
                     /locus_tag="PC592_001909"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF4055884.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYEQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GDYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAISLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            22058..22807
                     /gene="nagB"
                     /locus_tag="PC592_001910"
     CDS             22058..22807
                     /gene="nagB"
                     /locus_tag="PC592_001910"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF4055885.1"
                     /translation="MRVLVCKDYDAMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYKTVYGEITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPNDYKLV"
     gene            22982..23254
                     /locus_tag="PC592_001911"
     CDS             22982..23254
                     /locus_tag="PC592_001911"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055886.1"
                     /translation="MLKIIILSGILSSIIKLPIIGILPTGNIKKNTGINDSKKDGKQR
                     RSNLGISIYQLPLFLYSPINNSVPSNKPIPPEEIRLIKIYLLKSCI"
     gene            23914..24618
                     /locus_tag="PC592_001912"
     CDS             23914..24618
                     /locus_tag="PC592_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055887.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNLVNMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKVWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            24620..26107
                     /locus_tag="PC592_001913"
     CDS             24620..26107
                     /locus_tag="PC592_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4055888.1"
                     /translation="MKNGNDKNIIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTETVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTRENDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLVLFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSNVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKYASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEKMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKHNQKNIVVIVEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIINKHGGRIYVENGKKGAKFTILFKL"
     gene            26312..27925
                     /locus_tag="PC592_001914"
     CDS             26312..27925
                     /locus_tag="PC592_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4055889.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGLCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFIKEGFEIMFENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     FPLFLIPIFSLFLSVSVFDVSKFFSLECLKFLSLISSIGILYINFIVFYLFKFIIDKT
                     KLSMKYEILEKEIIHKEELRLSNERYKIIVEQTDSVVFEWNIKENKSFVSQAWNEKFG
                     YNNVCKNIFKEIKDKDLVHSEDNAIFENFLESIKKKNRHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELKTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQASFGSRDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(28140..29117)
                     /locus_tag="PC592_001915"
     CDS             complement(28140..29117)
                     /locus_tag="PC592_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4055890.1"
                     /translation="MIQCEIADRNSDKKINTLEVIIFFVVTYGISLLFGIPLYFKKYM
                     NPQIMVTFMTILPASGVAITKIYKHKKSDEHIILHCVIIADFLLSLFLVTLKAFGVID
                     DETILLGMGILVLFTGIITICYACLEGKELYPFKNVNKSIICIFIFIIIINLSKCIML
                     GWKDINFINLIMNIFLIFPYIANQSILFFGEEYGWRGFLQEKMQTKFGKRMGVILLGI
                     IWELWHIPLWFTVYHVDVLGILLRLFSVISLSIFFGYVYMKTKNVWSCVVIHLINNTV
                     LLDTDLNNAFLNFNASSLNSSIILGCLIFSVLLSLFIFSKEYKKEQLRY"
     gene            complement(29134..29964)
                     /locus_tag="PC592_001916"
     CDS             complement(29134..29964)
                     /locus_tag="PC592_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4055891.1"
                     /translation="MSQVPKNYFTTGEFAKICGVNKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLKEIKMPLKEIKTYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPITYKEQFLGDEEENFLYECI
                     NFIDNYELSDYGMIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKQKGLYVTA
                     YHKGSYETIYKTYEKLLNFFSQNNLCIGDFVYEEYLLYDISVRDSNEYLTQISAEVKI
                     "
     gene            30037..31764
                     /locus_tag="PC592_001917"
     CDS             30037..31764
                     /locus_tag="PC592_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055892.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGI
                     VKGDIDYIVKTGLMMIIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKVMTIIIV
                     VVMFLFMLSAFLVGKRLIRLFKIMQIKMDNMNRVLREVVTGVRVIRAFNRSHFEKKRF
                     DKTAIDYSETAISINKVFSVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNVYKDDVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISL
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            31802..33664
                     /locus_tag="PC592_001918"
     CDS             31802..33664
                     /locus_tag="PC592_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055893.1"
                     /translation="MSEKRTDKQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLVSAIFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRRAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPRGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHEELIEKKGFYEELYNSQFSSEYDEDVV"
     gene            33995..34684
                     /locus_tag="PC592_001919"
     CDS             33995..34684
                     /locus_tag="PC592_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HDF4055894.1"
                     /translation="MDKKLNYRFEMKHKITEADVLALKSRLYPIMKKDKNALKDGKYL
                     IRSLYFDTPEDKALLDKLNGVALREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSASL
                     TKTEVIKILNNDIEFLKESTNCLLREFYLKIKCERLEAKSIVDYDREAFVYPVGNVRV
                     TIDSDIKTSVNSIDLFNKHLPTVSIIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            34771..35457
                     /locus_tag="PC592_001920"
     CDS             34771..35457
                     /locus_tag="PC592_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HDF4055895.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKAFTKYQIKSKSVTPEKGIELVFEIRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            35474..37339
                     /locus_tag="PC592_001921"
     CDS             35474..37339
                     /locus_tag="PC592_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HDF4055896.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGIYSTSGNKGVDLYSDVYIEKYF
                     NRDKVMEVNIEIAESDLKDMNENAIKEEFKVAKVTIDGDTYGNVGIRTKGNSSLTSVV
                     NSDSNRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLSTPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGDVTGDLYKSDEGSSLQYKGDDPENYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLYNLIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDRNNSNNNSGNKSDEKEVTAELTLSEVKTNMDNETENNTTG
                     DSKNKNNTNDDKSGNGNNQKPEGSMGKGGKSIPGVLEVAKDMSKTIKAQLNGETSSTK
                     QNSGDESSSENKGTEKFDEDVGGMPEPPEGMDGKMPPGMGNMDNGDMNGKNGNMNRNQ
                     GNPREAGGFENKGGGSMSKTRTYSKLILGGASMIIMLIMLVGVSNINRRRFIKSK"
BASE COUNT        14781 a         3948 c         6478 g        12283 t
ORIGIN      
        1 aaaatagtaa aaggatatta taatatttta ctagaattat tatctggtaa actaagtttt
       61 gagtgtgaat ctaaagtata tgtttttata gggcttaaat tttatgtata caaaattaat
      121 ttgctaactg aatcatataa aaagacaaga tattttttag agggagtgat tagagagtat
      181 ttttttgttg tcaaattaac tgaagagtaa ttaattagaa aaggaatgaa taataatgaa
      241 tatattacat tattactttt gataaatcaa aaataaggtc agagttttta atattaatta
      301 agaatgatga aatatgaaca aagattttac aaataaacct taagctatgt tatttaattc
      361 taatgcggga agaaggtaaa tgtatattga aaaaatcata gaaataaaaa taaacaactt
      421 aaataaatac aaaggcttgc aaaataagta atataattat atacaatgag gatgtgagta
      481 tgatgaacag actaaagcca agaattttag gtattagtat cttgtttatt attataatta
      541 ttttaacatg tggagctatt ttcaagttta aatttaaatt agataataag ttaaaagaaa
      601 ccacacatac atacttgtct gagtttacag aacacaatat aattaatctc aagacaagac
      661 ttagtggtca atttgacatg cttgaatcca ttgctaattt cataggaaac ttgaataata
      721 taaatgataa aatggtgatt gatttaatgg actctaatgt aaagcgaagt tctttaatga
      781 gaatgactat ctccacatta gatggagaat gttattctaa tgatggaatt attcgtaatg
      841 ttcaagatag agactatttt aaaaaagcta aaaatggaga aaggaatata tcagagcctt
      901 taaaatctat tgttaataat aaagaaataa tagttttatc tactccagtt tataaaagtg
      961 ggaaaatagt tggtgtttta agtggaattt atgattcaaa aaagttaaat gaattattag
     1021 gattatctgc atttgatgaa aaagcagatg tttttgttgc aaataaaaat ggagctataa
     1081 ttgctcaaaa aacaaataaa aatagtaaga cactatcgtg tatatttcag ctctttaaca
     1141 aaaataattg tgatgaagtc tattgtctaa aaactataaa agaaaatatg aaaaatgata
     1201 aatctggata ttttaattat gacttagata atgaaaaatt tatgttaaac tatcaaccac
     1261 ttggagttaa tgattggtat gttttttctg ttgtgccaaa taaaatagtg tctattcagt
     1321 cagagaatat atcttatgat gtatatgtat ttgcattaga aatactatta gttatattga
     1381 tttttataat atatatagca tgtattataa ataataacac caaaattatt ataaatgaaa
     1441 aagaaaaatt taaagtactc actgataata tactaggagg agttaaaacc tgtttaaaag
     1501 atgaatatat gactatgaca tatgtaagtc agggattttt agaacttaca ggttactctg
     1561 atgaagattt aaataaaata tttaaaaata gatttaaaga tatgatttac aaagatgatt
     1621 tagacaagtt taattgtatt attctaaatc aattagaaaa acaagataaa attgaagttg
     1681 aatatagaat tgtaaaaaaa gatggaagta taatttggat tttggagaga agcaagtcta
     1741 taaatgataa taaaggaagt gagtgtattc aaggagtttt aactgatata acagaactta
     1801 agaaaataca agaagagtta gattcaaaaa gatttgaaat acaggccatc aatgatagta
     1861 ttgttggtgg gatagtgata actgagataa atgatgattt tgatagtata tatttaaatg
     1921 aaggttattt aaatatgatt ggatatacac gtaaacaact gaaggatgag ctaaataata
     1981 aattaataaa acttattttt aaagatgata gaatagggct aattaatagt ataaacaaac
     2041 aactcaaatt aagtgataca tttgcatctg aacaaagagt tgaaaaaagg gagggtacta
     2101 ttatatggat tttattaaaa ggaagaaaga taatttatga aaatggaaaa tctgtacttt
     2161 gttgtgttat tgtagatatt acttctgcta aattattaga gcaagaactt aaaaagagtg
     2221 aagaacgcca tgaaatcatt ctaaagcaga cgcaaaatat tataatagaa tgggatatag
     2281 aaaaagacaa aatgaatata tcacccaatt ggtataataa gtttaaatat gaccctataa
     2341 ctgaaaatgc aacaaaaaat ataattaaat cagtagatat atatcatgat gatatggata
     2401 agtttatttc actaattaaa cttacttcag aaggtagtga atatgaagag cgtgaaatta
     2461 gacttagaac tagagatact acctatgcat ggtttagcat aaaggcaaca accttatttg
     2521 ataataatgg taaaccttat aaggtagtag gaagtttgac tgatattgat gaatcaaaac
     2581 gagaagctga aaagttaaaa gaaagggcag aaaaagaccc tcttacagat ttgtataata
     2641 aaaaagcatc acaatcactt atagaagaat acataacatt agataaaaaa agaaaaggtg
     2701 ctttaatgat tattgatatt gatgacttta aaggaataaa tgataattta ggacatttat
     2761 atggggatgc tgtattaagt gaaattgcaa gtgacctagt aaatctattt agagcaaccg
     2821 atatagtagg tagaattggt ggagatgagt ttattgtatt tataaaagat atttctgaaa
     2881 caagagatat tataaataaa gcagaagaac tggtaaaaac atttgaaagg tcttttttag
     2941 gtaaaggacg aaaatataaa atatcattaa gtgtaggaat tgctaagttt ccacaagatg
     3001 gtatggacta tatgacacta tttagaaatg cggatatagc tctttactca gccaaaggga
     3061 aaggtaaaaa ttgttataca ttgtatgata aaaaaattga taaagttaaa tatataatta
     3121 atacaagaag tacagaagat attgacaatg tagagaagtc ttttaaagaa catattacaa
     3181 attatatatt tgatatacta tatgaatcaa gtgatataga agtggcagta aatttaattc
     3241 taagtattgt aggtaaacac tttaatgtga gtcgtatgta tatatttgaa aattcagatg
     3301 ataatctagt atgtaaaaat acatttgaat ggtgtaacga aggtataact tctgaaatta
     3361 ataatcttaa aaatatttat tacaaggatt taggtaacta tcttttaaac tttaatgcag
     3421 atgggctatt ttattgtaat gatattgaaa atttagggag tgatgtgaaa aaagtactta
     3481 aaccacaagg tatacgttca atattacagt gtaaaatttt agagggcagt gaatttagag
     3541 ggttcatagg atttgatgaa tgttcatata atcgtatgtg gactaatgat gaagtgaata
     3601 cattgacctt tatatctaaa acactcggca tgtttttatt aaaaatgcgt attcaaagta
     3661 agctagaaga gtctttaacg attcaaaagt ctgtaatgga taatatggac atatgggcat
     3721 atgttgttga caggaatacc tatgaattat tatttatcaa caaaaaaatg cttgagtcag
     3781 caccaaacac tcatgtaggt gatttgtgtt ataaagcgat atggaataat caaaataaac
     3841 cttgtaaaaa atgtcctatg atatatttaa aagatggtga tgatacttat aaatcattta
     3901 tgcgtaataa aaagtttgag atacaggcaa atataactac aactactttg aaatggtttg
     3961 atggtaaaga tgcatgttta atatttggaa gcgaagtaac tagtattgaa tctgaagaaa
     4021 atacttaaaa tactgtgtta tatatatact taaaattgca atttgaattt attagactta
     4081 aaatgtctat ataaatcatt taagttgtgg ttttaagtat tttttatgat ataattaagc
     4141 gttaagaaca aaattaaaag atacttttgt ataaaaaaat atttgttaaa tatatattga
     4201 gcaggtgata atatggaaaa taagttttta ccaataagca aacaagatat gatagataga
     4261 ggatgggaag aattagattt tgttctagtt acaggagatg cttatgtaga ccatcatagt
     4321 tttggaacag caataatatc tagagttcta gaaaatgctg ggtataaagt tggaataata
     4381 gctcaaccag actggagaac tacagatgat tttatgaagc taggaaaacc tagacttgca
     4441 tttctagtta atgcaggaaa tatggattca atggttaatc attattctgt aagtaaaaag
     4501 catagagaca aggacatgta ttctccaggt gggaaaatgg gatatagacc agatagagct
     4561 actatagtat attgtaataa aataagagaa gcatacagtg atgtcgcaat agtaataggt
     4621 ggaattgaag cgagtttaag aagatttgca cactatgatt attggagtga taaggtcaga
     4681 aaatctatgt taatagatag tggagcagat ttattagttt atggtatgag tgaaaagcag
     4741 attgtagaag tagccaatgc acttaatgat ggatatgacc cgaaatatat tagacatatt
     4801 gatgggacat gctatatttc agatactttg gaagaaatat atgataaata tatattaatt
     4861 ccatcttata aagaaatatg tgaagataaa atgaagtatg tagaagcttt taaaattcaa
     4921 tatgatgagc aagacccgtt tagaggaaat ataattgttc agcctcacgg aagtaagtat
     4981 ctggttcaaa ataaaccaga gaaaccactt aacagagaag aattagatga ggtatatgga
     5041 ttgccatatc aaaagacata ccaccctgta tatgaaaaat ttggtggtat accagctata
     5101 gaggaagtaa aatttagtat agtaagttca agaggatgct ttggtagttg ttcgttttgt
     5161 gcaataacat ttcatcaagg tagggcagta caaagtagaa gtgagaaatc aattattgat
     5221 gaagcaatag gaataaccaa tttagatgat tttaaagggt atatacatga tgttggaggt
     5281 ccaacagcta attttagaag accagcatgt aacaaacaaa ttactaaagg tgcttgtaaa
     5341 aatagacaat gtttatctcc atcaccatgt aaaaatctag atgcagacca cagtgaatac
     5401 ctacatttac ttagagctgt aagaaaatta cctaaaataa aaaaggtatt tgtgcgttct
     5461 ggaattagat acgattatgt aatggcagat aaaaacaata aatttcttag agaattgata
     5521 gagcatcatg taagtggtca gttaaaggta gctccagaac atatatcaga agaagtttta
     5581 aagtatatgc agaaaccagc aggaaaaacc tatgataaat ttagacagaa gttttttgct
     5641 ataaatgaag aattaggtaa aaagcaatat ttgatacctt atttaatgtc tagtcatcct
     5701 ggttctacct taaatagtgc tatagagtta gcagagtatt taagagatac tcactatcaa
     5761 ccagagcagg ttcaggattt ttatccaact ccagggactc tatctacaac catgttttat
     5821 acaggtattg acccacttac aatgaagcca gtttatgttc ccaaatcaaa acgtgacaag
     5881 gcaatgcaaa gggctttatt acaatataga gcacctagaa attatgattt ggtatattct
     5941 gcattagttg aagcaggaag agaagactta attggttttg gacatagatg ccttataaag
     6001 ccaaaaagtg agaagcctta ttttaataga aataattcta aaaaaaatgt atctaaagga
     6061 acaaataaaa acaaaaaaac taatacaaat aacagaatta ataaaaatca acaaaaaagt
     6121 tcaactagaa aaaagaaaaa gcattaaagt gtaaataaaa atacttaaaa aagaaggatt
     6181 attcgataaa ttaacagaaa ttagtataaa taaatataat tattttaaag gcgttacctt
     6241 tgggaggaag agatgaaaaa gtatatttct ataatattat tagtggtgat ggctatggtt
     6301 gttttggtag gatgttcacc aggaaaagat aattctcaaa ataaggagtt atcagttgtc
     6361 aaacaagtga aagtagctgt tccagatggg ctaccagcag tggcaatagc caaacttgca
     6421 aatgaaaatc cagagattaa agatggatat gaaacagtgt atagcattga aaagacacct
     6481 gaggcgattt ccactagagt gatgaaaaaa gatgcagata tagctatagt tccttcaaac
     6541 atggctgcga tagcttataa taaaacttca tcatataata tagttggaac tgtgggaatg
     6601 ggttcacttt atttggtatc aacagaaaat ataaaagact attctgattt agttggtaaa
     6661 gaagttggat gtactggaaa aggacttact ccagatataa ctataaaaag ccttttgtta
     6721 caaaaggata tagattattc agatataaat tttaattatg taaattcagc aagtgaatta
     6781 gtaccattat tggctactgg taaagttaaa acaggtattg ttccagaacc tgcacttagt
     6841 gctttgatgt ctaaaaatcc agatataaaa attataaaaa gtttaaatga ctcatggaag
     6901 gaagtaagtg gctcaaaaga tggttatcct caatccactt taattgtaaa atctgagttt
     6961 ttgagagata ataaagattt tgttgattct tttgtaggtc aattatcaaa tagtatagat
     7021 tgggcaaata aaaatcctga agaattaggt gcatattctg aaaaaataaa aatatctact
     7081 gaatcaaaga taataggaaa atctcttgaa agagctaatt taaaatatat tccagttaaa
     7141 gacatgatta aagactataa aaattactat gagaaattag ctaattttga tgataagaca
     7201 ttaggaggca aagtaccaga tgaagcaata tactttgttg agaaataaaa aaaataaaga
     7261 acaatttata gataaaatgg aggtaacact ttcttgtgtt atcctcttat ttttatggca
     7321 aattattgct ttaaaaattg ataatgatat ttttttacca acagtaggtc aagtatttaa
     7381 tagcataaaa gaaattatac taaattctag tttctatata gatatacttt actctatagg
     7441 gagatgtttt tttagttttt tactggctat gttttttgcc attatacttt caatagtgtc
     7501 ttatttaaat agatttttta gaaatttatt aaaaccaatc aatgctttgg cacgttcaat
     7561 accaactatg atattggtag tacttgcact tatttggttt gaaaaggata gtactccttt
     7621 tatagttgga tttgctatcg ttttccctat attatatgat aacgttttgg gagctatatt
     7681 gaatatagac aagagcttac tagaaatggc tagtgtgtat aaaataaggt ttatagataa
     7741 ggtattaaaa atttatttac cagttataaa atttcaaatt atatctatac tagtatcgac
     7801 attctcttta agtttaaaag ttgctatagc aggagaagta tatagtcaac ctacatatgg
     7861 tattggaact atgatacaga ctgaaaaaat taacttcaat acatctggaa tatttgcatg
     7921 gataattatt gttcttttaa tttctgccat tttgcaaata gctcaaaagt ttttagcaag
     7981 gagagctttt ttatggaaaa gataaggtta agtattgaga atataaataa aagatatgat
     8041 aatcgtatta tatttagaga ttttaatatt gatttttatg taaatgaggt aaattgtatc
     8101 cttggaaaat ctggttgtgg aaaaactaca ctcttgaata taataagtgg gattattaaa
     8161 aatgatacca acaatctaaa tatcaaagaa aatttaaata aagtaggaaa taaacttgaa
     8221 gctagttaca tatttcaaga tgatagactt atagactggt taacagtaga agaaaatata
     8281 aagatagttg taaataaata ctataataaa actaaattaa ataaaatttg tgatgaatac
     8341 ttagaattgg ttggaattag tgagtataaa aaattctatc ctcagatgct tagtggaggt
     8401 cttagacaaa gggtaaatat tgctagagct tttatatatc catccaaaaa cattataatg
     8461 gatgaacctt ttaaatctat tgatgcaaag aatacacagc ttataatgga taatttcaaa
     8521 aatatattaa gaaaagagaa gagaactgtg ttatttgtaa ctcataatat tgaggaagca
     8581 ttgtttttag cagataggat atttatttta ggagattctc caattagaat aaaaaaaata
     8641 ttaaaaaatt ctaatgaatt ggaaaaaaat gaagttttga agttgatata gagttataat
     8701 aatactatcg ttttaaaaca tatttgttta aaatatataa gactctgtta atatggtaca
     8761 gaatattcaa aaatgtgtat aatgttcgta ttttataaaa aggaagtgaa gatatggtta
     8821 agactaatgc tatgagaata ttagattcaa ataagattga ttataaagta atgtcttatg
     8881 aagtgaaaag tgaacatgtg gatggtgttg aggtggcaca tgatatagga agagatgtaa
     8941 atgaagtgta taagacattg gtaactcaag gagttagtaa gaatatatat gtatatgtaa
     9001 taccagtaca tgaaaactta gatttaaaaa aagctgcaaa agtagctaaa gagaaaagtg
     9061 tagagatgat tcatgtaaaa gatataaata agtttacagg ttatattaga ggtggatgtt
     9121 ctcctatagg catgaaaaag ctttataaaa cttttgtaaa tgaaagtgca aagaatttag
     9181 atacaattat tgtgagtgca ggaaaaatag gatatcaaat agaactatct ccatttgatt
     9241 tacaaagact tataaaagta gaatttgtag atgtaataaa aaaataagaa tcacatataa
     9301 aatatagaga ttatattctt aataacaggt gttgtagtgt taataaaatg aataataatt
     9361 ttaaaataaa tattcaatta cttatgtgta attgatataa aaatattgag aaattttaaa
     9421 aacaatggta aagtgtaagt gtaatcacga atatttttta taaagtaatg gagggatgtt
     9481 cgcttgagaa aaataaaatc tgaacaaata gtcgaacaag taaaaaaact ttgtatagaa
     9541 gcgagcctat atttaggaga agatgtttta ggttgtataa aagagaaagc taaaagcgaa
     9601 aagagtgaag ttggaaaaaa tatattaaat atattagttg aaaatgctga aatagctaaa
     9661 gaaaaaaata taccaatatg ccaagatact ggtatggctg tattttttgt tgaagtagga
     9721 caagaagttt taattgaagg agatacgctt actgatgcga taaatgaggg agtaagacaa
     9781 ggctatgaag aaggctactt aagaaaatct gttgtaagcc caattaatag agtaaataca
     9841 aaagataata cacctgctgt tattcattat gatatggtaa aaggtgataa aattaaaata
     9901 gaatttgcag ccaaggggtt tggaagcgaa aatatgagta agatgaaaat gttaaaacca
     9961 tcagatggac tagaaggaat taaaaaattc ataatagata cagtttcaga agctggacct
    10021 aacccatgcc ctcctatggt aattggagtt ggtataggtg ggactgtaga caaatgtgct
    10081 caaatagcta aaaaggcact ttttagagaa ctaggtgaat ttaataagga tgaaaatata
    10141 gcaaagcttg aaagtgaact attaacatct attaataaac ttggtatagg gcctcaaggt
    10201 ttaggtggta ctacaacagc tttgggatta aacatagaga cttttcctac acacatagca
    10261 ggtctacctg ttgttgtaaa tataaactgc catgcatcaa gacataagaa ggtagtaatt
    10321 taggaggaaa ataaaatgat aaaaataact acacctgtaa gtgagattga tatagcaaaa
    10381 ttaaattgtg gagatacaat tagcttgagt ggtatacttt atacagcaag agatgctgct
    10441 cataaaagat tgatagactg tataaataaa ggtgaagaat taccatttga cgtatatggt
    10501 caaggaatat attatgtagg acctactcct acaaagccag gagaagttat aggtgctgct
    10561 ggaccaacga caagctatag aatggatgat ttgactatac ctcttttaga gagaggtctt
    10621 aggttgatga taggtaaggg aaaaagaagt gacgaagtta tagaaggtat gcaaaaatat
    10681 ggagcagttt atcttgctgc aataggtgga gctggagcat atatttcaaa ttcaataaaa
    10741 tcatgtgaaa ttattgcata tgaagattta ggagccgaag ctataagaaa gattgtagta
    10801 gaagacctta aacttacagt agccatagat agctatggta ataatatata tgaacaaggt
    10861 cgagcaattt atgaatgtaa ataaagttta gaaatttata tgaatattaa aattaaaaat
    10921 agttgtgtat attttaagga ggaaaattga tgtctaagga ttatgcaaaa ttggcattag
    10981 aaatgcatga aatcaacaaa ggaaaaataa gtgtagaaag caaggtagaa gttaaaacta
    11041 aggacgattt atcaacagca tatacaccag gtgttgcaga accttgttta aaaatacatg
    11101 aaaatcaaga tgatgtttat agatacactt ctaaagggaa tctagtagca gtagttagtg
    11161 atggaagtgc tgtacttgga ttaggtaaca ttggtgctga agcatctata cctgttatgg
    11221 aaggaaaggc catattattt aaacaatttg cagatgtaga cgcttttcca atatgtttaa
    11281 agactaatga tgtagatgag atagttaaat ctgtagagtt gatggaacct gtatttggag
    11341 gtataaattt ggaagacata tcttctccaa gatgttttga gatagaagag aggctaaaaa
    11401 aatctttaag tatacctgtt tttcatgatg accaacatgg gacagcaata atagttgcag
    11461 cagctgtaat aaattcaata aagttaattg aaaacaaaaa aatagaagat ttagaaatag
    11521 ttataaacgg agcaggggct gctggtatag caatagcaaa gatactactt aatatgaatg
    11581 ttaagaatat aatcttatgt gatagaagtg gtgcattgga atctagtgta gaaaatctaa
    11641 actatgttca aaaagaaatg ttaaaagtaa caaatataag aaatgaaaaa ggacctttaa
    11701 aagatatcat aaaaggaaaa gatgtattta ttggtgtttc aggtccagga gctgttacaa
    11761 aagaaatggt tgaaagtatg tctgaaaagc caataatatt ggcaatggca aatcctactc
    11821 cagagataat gccagaagaa gcaaaattag gtggagcatt tataatggga acaggtcgtt
    11881 cagacttccc taatcaggtt aataatgtct tggcttttcc tggaatattt agaggtgcac
    11941 tagatgtcaa ggctaaagag ataaatgaag agatgaagat agctgctgca tatgcaatag
    12001 ctaatactat aagtgatgaa gaaatatgcc cagagtatat attgccagac gtatttaata
    12061 agaatgttgt aaaaaatgtt gctaaggcag ttaaagaagc agcgataaaa accaaagtaa
    12121 atagaatata aatttttata tgttcatata tccttatctt atcgggtata tgggcatttt
    12181 tattataggt ttatactcat atatccttac ttttatatac atatctttat gattaaaggt
    12241 gttagaaaat gtagtaaatt ttatactatc agactctatc tttattactt tagtagatac
    12301 atggttgtaa aggtttatag aaaaaaatat aggaaggcag atttttattg ttgcgtatat
    12361 atgagaatga tataatatga atattataaa ttaataaatt taaatttatg gaggtacaag
    12421 agatgatgga atataaagtt aatgaccaag aacttaatgc ttcaatgttt gtcccattcg
    12481 tcaacaggat atggccagga gattatgata tggataaaac acagactgca ttatcaaaaa
    12541 ctttgaatat aactgcttat gatgataaag tgcttgtagg atgtctgcga gttctttcag
    12601 atggttatta ttttggaaca attacagaat tgcttgttct tccagagtat cagaaacaag
    12661 gcattggtag taagcttttc cagcttgcta aagagaacac cccaactatg ctatattttg
    12721 gtgcacagcc aggagtagaa gcgttctatg aaaaaaatgg gtgccaaaga agtctgcaat
    12781 cctacataat aaaaaagaaa gatagttatt aaagttccag ctttcaataa tcttaaaagt
    12841 acaatatttt agtggaatca tttcattttt tattactaat atgacataaa catgtcatat
    12901 tagtattgat atacttttaa tatggttaag agccaaagaa aaatataagg agtgatttaa
    12961 aatggaagaa actaaatttt gccaatgctg tgcaatgcca atgggacaaa ctgatgaatt
    13021 atatgggaca aataaagatg gaagtaaaag tactgattat tgtagttatt gttttaaaga
    13081 tggtgagttt acagctgata taagtatgga agagatgata gaagtttgta tccctcatat
    13141 gcttcaaagt aataaggata tgactgaaga tgaagcaaga acaatgatga acaatttctt
    13201 tccaacatta aaacgctgga aataatttta tgcaaaatta gttatatgca aaacatgaaa
    13261 tatggtgttg agaataaggg gtggtgtgct ttatagcata ccacctgttt tgttacttgc
    13321 tagttcagtt attcttgtat gcttaaatat gttctcatcc ctctttctat ttcaaattgt
    13381 gaaaatctaa aatatgttat ttatattcta cttctatatc catgtctttt tatacctcaa
    13441 gtcaaatcca actacaaaat cattattttc aattctctgt ttaactatta acagataaag
    13501 aattataaaa ttttctattt tttatataaa ataatacagg tcaagctgat ttctagctat
    13561 ttgagataga aagagggatg agagttatag gagtaatacc aatcattaga ctgttgattt
    13621 gtgtagtctt ttgtaaaaac atttgtttta atatattgag tttttgaaaa agtaaaatta
    13681 taattaaaat aaattaagtg taataatgta ttagaagtaa aaataattaa aatagaggtg
    13741 attaaatgag tagtatattg ttagttgaag atgatttaag cttgatatat ggattagagt
    13801 tctctataca aaaaagtgga tttagtatag acatagcaag gacagtaaaa gaagctatgc
    13861 aaatgtatga ggaaaaaaat tatgacttat tgcttttaga tgtatcccta cctgatggta
    13921 atggatttca gatttgcgaa aaagtacgag aggtttctaa tatacccatt atatttttga
    13981 ctgcttcaga tgaagaggta aatgtagtga tggggcttga tatgggtggc gacgattata
    14041 taacaaaacc ttttaaatta aatgaattaa tttcaagaat aaaagcatta cttagacgtt
    14101 ataatgttgc aagtaatgtg aatgaattaa gttcaaataa tattactatt aaattacttg
    14161 aaaatcgtgt ttttaaaggt gaatttgagg tggaacttac cacagcagaa tataaattat
    14221 tgtgcttatt tatgaaaaat aaaaatattg tacttactag aaaaaacata ttggacaagt
    14281 tatgggatgg aaatggtagc tttatagatg acaatacatt atcagtatat gtaagacgat
    14341 tgagaaataa aattgaagat aatcctgaaa accctaagtt tctattgacc gttagaagaa
    14401 tgggttataa atggaatgta attaagtgag ggtattaata tgaagatatt ttctaataaa
    14461 gatataaaaa tgtttttttt aattcttata tctattttag taatgtttat tatagtaggg
    14521 caaatagtgc ttataagtat aactaacaat tataaaaaaa cgttgataga acatgattat
    14581 aatatagctg gatacttata tagtataggt gttgataaat ctaaaatacc atcagcattt
    14641 gttgtacatg aagataaata tattttaaaa ggaaaagaaa tactagatac agctggatat
    14701 ggatttgata tagatgttag ctttacacca agtgtaaaat tgtttcaaag taaatatata
    14761 aaaactatgt ctatctattt attagtattt tttactatga ttattttcat accatatatg
    14821 tattttttta ggcaacaaag taagatagaa gaggctagtt ataaaattga ttcatttatg
    14881 aatggaaata taaatgaaag actaaataca tatgaagaag gtagcttatc aaaattattt
    14941 agttcaatag atgttatgtc gacatcttta aatacacata tattaaaaga aaaacagagc
    15001 agagaatttc ttaaaaatac aatttcggat atatcgcatc aattaaaaac tccacttaca
    15061 gctttaataa tgtacaatca gatactacaa gaagaaagtc ataatagtga tgttgttgaa
    15121 gcttttgtac aaaaaagtca aagtgaacta gaacgcattg aaacattgat taagaattta
    15181 ctaaagatta caaagataga ttcaaaaaca atagttctca ataaaaataa tgttaatctt
    15241 aaaaatttaa ttgtcaaaat tttgtatagc tttgaaacta gggcagaaaa agaaggaaag
    15301 gttatttcta taaagggttc agaaaataca ttgttgttct gcgattatga atggatgtca
    15361 gaggctttaa gtaatcttat aaagaatgca ttagataata caaaagagaa tgataaaata
    15421 acgatagagt ggtttgagac gactataacc accattgttt cagttaaaga cactggaaat
    15481 ggaatccatg ttgaggatat tcatcatata tttaaaaggt tttatagaag taagttttca
    15541 aaagataatc aaggtttagg actgggatta ccactagtta aatctattgt ggaacaacat
    15601 aatggtacta tttctgtaga aagtaaacta tcacaaggaa gtacattcac cataagtttt
    15661 ttaaagctta ctaatatgta agataaaata catcttgcag taaggtatat agattattat
    15721 tatattaatc aattagaaag gtgagagaga aaatggatat tcttgtggtt aataatttat
    15781 gtaaaacata tggaaatgga tatacaaaag tagaggcatt gaaagatgta tcctttacag
    15841 tttcaaaagg agagtttgtg actgtagttg gagaatctgg ttcaggaaag agtacactat
    15901 taaatctctt aggaggtctt gatactccaa catcagggag aatatttatt gatggtaaag
    15961 aaatatgttc aatgaaagag gaaaaacaga ctatttttag acgtcgtaac atagggttta
    16021 tatttcaggc atataacctt ataccagaac taactgtgga gcaaaatata atattcccat
    16081 tgttattaga ttataaaaaa ccagatacta tttacttaga tgaagtattg actattttag
    16141 gtcttaaaga taggaaaaat catcttccaa atcaattatc tggtggtcaa caacagagag
    16201 ttgcaattgg aagggctttg attacaaagc caagtattat actggcagat gagccaacgg
    16261 gaaatcttga cagtaaaaat agtaatgatg taatttcact tttaaaagtg actgcagaaa
    16321 agtataatca aaccattatt atgataactc ataatacgaa tatagcttct acagcagata
    16381 gaatactaca ggtttctgat ggtgtgctta cagacctggg ggtgaataga gaatgagaag
    16441 ctacttagaa ttagtaccac aatatgcaaa agtacataag aaaaaaaata gaactacaat
    16501 tttatgtatt attattgcag tatgcttagt tactgctatc tttggacttg cagatatggc
    16561 tatacaatgt caaaagatac aatttattaa agatgatgga aattggcaca tagtaattag
    16621 aaatattgat gaaaagttta tatcagaaat aaatagtaga gtagatatag ctcaccatgg
    16681 tagggggcaa gtcgttgaca gtggagagtt taaatcaaag gagattttga tacaaggttt
    16741 agatgaagaa gtagcaaaac aatttaactt agaaataata aggggtcgtt atcctattgg
    16801 ggagaatgag actttaatag atgaggatgc agttaaaagc tttaatctaa aaataggaga
    16861 ttttatcaaa ataaaattag cagatggtag aaataaaaat tataagatag taggtgaata
    16921 ttcatcaata tcaagcttaa gagctacaga taaacatgga ttaatacttt caatattggg
    16981 tacacaagct attaaaaaat cagaaacgta cgattattat tatattacat ttaaagaaaa
    17041 ggttaatatt agaaaagcca cttctgatat taaaaatacc ttcaatttaa gtgataaaca
    17101 aatcggtaaa aatgaaagat tactttctat tataggtcaa ggtgactctg acttttctaa
    17161 accactgtat ttaacagcag gattactttt tgtacttgtt ttagtagcaa gtattatcat
    17221 gatatataat agttttaaca tgagtgtaat tgagagagtt aaattttttg gtttgttacg
    17281 ttgtctaggg tcatcaaaac atcaagttaa aaaatttgtt gttttagaaa gtttaatttt
    17341 aagtataaaa gctattccaa taggcttagt attaggaagt cttgtaacta ttatatcttc
    17401 tatatttctt aagtatgtta atgagttatt cagctcaatg ccaattttaa aagttagttt
    17461 tattggtatt gcatttggaa taattgtagg gtttttaact gtaatattat cagctattat
    17521 tccagcaaaa aaagcttccc gtgtatctcc acttagcgct gtacgtggga atctaatgtc
    17581 caaagaaatt ttaaataacg gaaagacaag taaagttgca aatacaggaa gttttaaaat
    17641 tgagacttct atgggattaa atcatgcttt ttcaagaaag aaatcttttg tacttatgac
    17701 ttcttcattt gccattagta ttatactatt tttaggtttt agtgtgctta tagaccttat
    17761 gtatcaagga cttaagccta tgaagcaaga agctcctcat atatctattg ttgaccctaa
    17821 ttttaagtct gttttaacta aggaagatat taatgaaata agtaatatca aaggagtaaa
    17881 gaaagtatac agtagaatga tgacggatat agaagctaca tataatggga agaagacaaa
    17941 atcacaatta atttcttatg aaaagtatca atttaattgg gcaaaaaaat atctattaaa
    18001 aggagaagtt aatgaaaata aactacagtc agaaaacctt gcattagtag aagaggggca
    18061 tggatttgat ataggagata agatatatat taaaaatgga aatgctgaaa aagagttaga
    18121 ggtaggaggt atactttcct caattccatt tgaggttaaa gataaatata ttggaaatat
    18181 tataacatct gaaaatactt ttacgaatat aacaggtata aagggttata taataatgga
    18241 cattcaggtt gataaagata cttctggaga tttaattgaa aatataagac gtgtagtaga
    18301 tgataactta gaggtcagag ataaaagaca aagtaactta gaggttaaaa attcgtttta
    18361 tactatggca acatttgtat atggatttgt gtttattatt gcgattataa gcatgtttaa
    18421 tatcataaat agcatgaata taagtgttac aagtagaaag aattactatg gtgttatgcg
    18481 tgcagtaggc atatccaaca gacaattaag aagaatggta atagtagagg caggttcata
    18541 tgcagtgagt ggttgtttat taggtagtat actaggatta atgttacata ggtatatgtt
    18601 tatatcgtta gtaagctcaa tgtttcattt agagtggcaa gtacctttta atttactact
    18661 tatcactgta ctaactatga taataataac tttattatca gtaagaaaac cagtcaaaaa
    18721 gatttgtgaa ttagatataa tagactcaat aaatgcacaa taaatatagc tattgattta
    18781 aattaaaaaa acaaagtaaa aatgaaatag aaaatatttt tcatttttac ttcgtttttt
    18841 atattgtaaa atttttgtta tgttacaaaa tttctataaa gatgatgtga atctaaacat
    18901 tatatgacaa cgtgagcatt taagttaaaa tattttaaat atactatttt agataagttc
    18961 cttcttcatc ttgataaatt aatccttttt tcataagcac tccaagagct cgtttaaaat
    19021 ttttcttact tgaattaaat aatatagaaa tatctttagg gtcagactta tcattaaatc
    19081 tcatatatcc atcagaaccc tctaaataac ttaaaatttt attttctaaa gtatcaagtt
    19141 catcctttct atttcctcta ggagaaagac caagttttcc atcttcatat atttttatga
    19201 catgtaaatt ttcaagaaca tcaccagttt ttagttcagt aaagtactca ttatgaagta
    19261 ttacaccagc atatttgttg tctacacata tcattgcaga attattagtt tggaatccat
    19321 atacaactcc agttacaata tctcctacat tgtaagtatg gtctgttaat aagtatgaat
    19381 ctatatctgt agtagcagca attcttttgc ttttgtctaa atatatataa aataaatatt
    19441 tttcgtctct aaatagtgga taagtcttag ctttaaaagg aactagtata tctttaggaa
    19501 gtcccatatc tataaaagta ccaatgtctg tattatcaac tacttttaag cgtgctacat
    19561 ccccaacctt agctaaaggc ggtattaaag ttgcagcagt tctgtcatca gaatctttaa
    19621 atatgaaagc atttacttca tcacctatgt ttatttcatt ttttccgatt aatctattat
    19681 gaagaagtat atcatctttt gtgttattag tttgtccatc caaaaaatat ccaaattcag
    19741 tttttctttt tactgtaagt ttattaaaat cacctatgtt tatcaaatta aaatcatcct
    19801 ctcattttat gtttataatt tagccataat atacttatgt agtagtttgt cacagtatct
    19861 atattagtat tagtgaaatt tacaataaat aatatagtta tttatgtatt tttcaattct
    19921 ctagcttctt atatagtata aactccaatt tcttttttgt ctttaggttt tactaaaatt
    19981 tttacaaaat aaattaaaaa gtattgaaat aaaatttctt ttaaagtata attggtatat
    20041 accaaaattg gtatatacca tattgaaaag tggtgattaa tatgaaaata gtaaataaat
    20101 ctagtaacat accattgcat actcaattaa gttcaataat aagagagatg atagaaactg
    20161 gtgagcttaa agaaggtgat gcaataatgc cagaaagaga actttgtaac atacaaaatg
    20221 taagtcgtat gacagtaaat aaaactattg ttggattagt aacagaagga cttctttata
    20281 gggtacaagg taaagggaca ttcgttgcaa agcaaaaaaa gaagtatcag ttttcaaatg
    20341 taaaaggttt tactgatgtt atgaaagaaa agggagtaaa cataaaaaca gatatattat
    20401 cctttgagat ggaactacca gatgatttag ttaaaagaaa gcttggaata agtgataata
    20461 ctacaaatat atataagatt gtcagactta gatatactga cggagagcca tttggattag
    20521 aaatagtata tctatcagaa gaaatgtgta agggtctaac aaaagggata ttggataatt
    20581 cttcattata tagggtttta aatgaaaaat atggctataa gatacaaaaa gctgaacagg
    20641 taatggagcc agtaatactt tcagatgaag aaagtaagct tcttgaaaca gatgaaggtg
    20701 ctttagctct taaacttcat agaaattcct ataatagaga aggtaaccct atagaatata
    20761 ccatatcaat atttagaaca gataaatatc aatatgaaat agtattgagt gagtaggtga
    20821 ataatatgaa atgtttaatt aatggaaaga taatattaaa aaatcaaatc ttggaaaata
    20881 aagtactagt atttgatgaa aaaataattg atatagctga tagtgtacca aaagattgtg
    20941 aagttataga tgctgatgga aaatatatat ctccagggct tattgatatt catatacatg
    21001 gaaacatggg aaaagataca atggattcaa ctgatgaatc tattgaaaca atttcaaagt
    21061 caataatgag acatggagta acatcttttc ttccaactac aatgactatg gataaagaac
    21121 atgtttatga tgcacttgaa gttattaaaa aagcccaaaa tagaaagctt gaaggggcac
    21181 aagtattagg agcacattta gaaggacctt ttataaatga gaattataag ggagcacaaa
    21241 atgaaaagtt tataataaac tcaaaatacg aatttataaa agaatataaa gatgttataa
    21301 aagttataac ttatgctcca gaaaaagata ttgattttga ttttactaga gaaataaaaa
    21361 gatgtacaga tatagtttta tctattggtc atagtaatgc aaattatgag caagctaaag
    21421 aagctataaa tttaggtgta acaaatgtaa ctcatatgtt caatgcaatg actggtttaa
    21481 accacagaga cccaggcgtt gttggtgcag cacttacaac taatgtgtac agtgaactaa
    21541 tagcagatac aatccatata aataaagatt tatttcaatt tatactaaac aataaaggta
    21601 aagaaagatt gattttaata acagattcta tagaagctgg tggtcttgaa gatggagatt
    21661 attctcttgg aggtcagaaa gtcatagtta aggggaatga agctagactt gaaaatggag
    21721 cattagctgg aagtgtgttg tctttaaata aaatggtatt taacttctta gataatacaa
    21781 accttaaggt gaatgaagcg attagtttag catctttaaa tccagcaaca tctttgggaa
    21841 taaatgacaa aaaaggaagc ttagaaatag gcaaggatgc agatatagct gtatttgatg
    21901 agaatttaga ttgtaaaatg acactttgct tgggggaagt agtatataaa aatatatagt
    21961 atacagaaca aactttaaag acagtaaaag caatataaaa aataataaat taaacttacc
    22021 ttagttgaaa tagtagttaa aatttaggag gaacaagatg agagtattag tgtgtaaaga
    22081 ttatgatgca atgagtaaaa aagcagctga gatgatagca gctcaaatag ttttaaaacc
    22141 aaattcaata ttaggactag ctacaggaag tacaccagta ggtatgtata gagatttggt
    22201 aaaaaaatac aatgataata tagtagattt ttcagatgtg atgagcttta atttggatga
    22261 atattataag ttaccaatat ctaatgacca aagttatgat tattttatga aagagaatct
    22321 atttaatcat gtaaacataa agccagaaaa tactcattta ccaaatggaa tggctgatga
    22381 tattgaaaaa gagtgtatga actatgaagc ttctatagat gcagctggtg gtatagatgt
    22441 acaagtactt ggaataggtc gtaatgctca tataggtttt aatgaacctg atactaaatt
    22501 tgcaaaaaga actcatgtag ttgaacttac agaatctaca atagaagcta atgcaagatt
    22561 ctttaaatca agagaagatg ttcctaaaaa ggctgtaagt atgggaatag gttcaatatt
    22621 aaaatctaag aaaatattac ttttagcttc aggagaagaa aaagctgatg cggtatataa
    22681 gactgtttat ggagagataa ctccagaagt tcctggttct atacttcaac ttcataagga
    22741 tactatagtt atagtagatg aagcagcagc aagtaaattg aatccaaacg attataaatt
    22801 agtataataa tagaatgtag tttaagtaaa aaatagctat cattgaataa tcaaatttat
    22861 ttaatgatag ctattattat ttaaatcact tacttttttt catttaaatt agttattatt
    22921 gtttaaatta cttgtttatt actttttacg aaaactcgtt atcaagaagt atccaaataa
    22981 gatgttaaaa attattatac tcagtgggat tctatcaagt ataataaaat tacctataat
    23041 cggaatatta ccaactggaa acataaagaa gaatacaggc atcaatgata gtaaaaaaga
    23101 tggaaaacaa agaagaagta atcttgggat atcaatatac caactaccac tttttttgta
    23161 ttcaccaatc aataattcag ttcctagtaa taaaccaata ccaccagagg aaattaggtt
    23221 aataaaaata tatcttttaa agtcttgcat ataaccagtg tgaaatcgga aataaaaatc
    23281 ataatttaat ttaacagcta agaaatacat aagcaataga ataattaaaa ataaaaaata
    23341 tctaagagtt tttttcattt taaattctcc cttcagaaat actttatcca gttttatttt
    23401 gttggaatat gattttatca tttagtttaa gaaatccata atattagtga agaatgaaaa
    23461 aagtactata tatgaataaa tatttttaga attaaggtga actgtagtac ttaatataac
    23521 tataatatta attgtttgaa tattcaataa aaagtttgaa aaatatcaat tttgatataa
    23581 aatgaataaa tacagttgaa tattgaatta ttattttatc aaaaatatgc aaagtactac
    23641 actttcaaat gtcacctaaa gtaataaaag gtaattaaag tgaagtagtt caagatattt
    23701 ctaaaatgag tttaataaat tctataataa tttatttttt gccttaaaat tgccttaaaa
    23761 tccaaacaat tttaaaacta atgtactata aaaagctggt ataatttaaa tatagtaaaa
    23821 aataagattt atcttatcta ttgggattca attatttaat caatatattt atactattta
    23881 atttaaataa aaagtctatt aaggagtgag cttatgagta aattaattta tatagcagat
    23941 gatgaagata atataagaaa tttggtaaag acattcttga aaaatgaagg tcatgatgtt
    24001 atggatttta aaacgggtga tgaactttta gaacaattta atataaaaga gtgtgactta
    24061 gtaatactag atataatgat gcctggttca agtggttttg aagtatgtac aaaacttcgt
    24121 gagaaaagta cagtcccaat aatcatgctt actgcaagag atacagatat agattatatt
    24181 acagggataa ccttaggtag tgatgattat tttacaaaac catttagccc aatgtctttg
    24241 gttatgagag taaaatctat atttagaagg atagagtttg aaaaaaaaca aaattatgat
    24301 aaatatagta acttggtaaa tatggaatta aaatttgggg atgtaataat aaataaaaag
    24361 aataaaatcg ttacaagtaa aaatgtaaat atagacctta caccaaatga atataaccta
    24421 ttgacttatt tgtttgaaaa tatagataga gcagtttcaa gagatgaatt attaaacaaa
    24481 gtatggggat acgatataga agttgagaca agggctgctg atgatacagt gaagagatta
    24541 cgtaaaaaaa ttttagatac aaatatttta atagaaactg tatgggggtt tggatttagg
    24601 ttgaaggaga aaagttaaga tgaagaatgg aaatgacaag aatataattg gaaagattaa
    24661 atccaaattt aaattaaagt tctcaaagaa aaatataagc ataaaaacta ggattttgtt
    24721 gagcatactt tgtttgataa ttatagtatt tatgataata ttagtatctt ttaatgtatt
    24781 tcttgataca tatataaaaa caactgcgaa tgaagaatta acaaagtcta cagaaacagt
    24841 agaacatatg gatagtaatt ttagacctat taagccacca caagatgatg gaaagcttcc
    24901 tcccaaagta ttatctaatt ttatgagaaa tgtacaagat aaagttagga tggcagaaac
    24961 acaatcagat gctgatgcta tggtagttga ttctaagtat aacctgatat ttccaacaag
    25021 agagaatgat ttcttaaaaa atgttgatga gatggagctg attagggagt gtattcaaaa
    25081 tgaaaaatta gatttaaatt cagatgaaaa tacacggata tctaccagaa ataaggatta
    25141 ttatatttca actgtaaaaa ttactagtat atatggtgaa caagacaagt atcttgtact
    25201 ttttatagac atatcaaaaa ctctaaatct agcacaaaag ataaatattg tattaatatc
    25261 tgtaatgtgt tttgctggaa tattagcaat atttacagct gtgattttat ctgagaaaat
    25321 tgctaaaccg ataaaagagt tgtgtgaatt tgcaaaaaaa atgggtcaag gagatttcaa
    25381 aagaacttac tttgattttt cagataaaga attagtagag ctttcaaatg ttatgaataa
    25441 gagtgctgag tatctggata agtatgataa tgagcaaaaa atattttttc aaaatgcatc
    25501 tcatgaatta aggacgccac tcatgtctat taaaggttat gcagaagcta taaaatataa
    25561 tgttatagat agtaagtatg caagtgatat aattcttgaa gaaagtgata ggttaagtga
    25621 tatggttgaa gatttattat acatttccaa aatagataat ataactaaag attttgaact
    25681 tgtagaatgt gatttaagag aagtactttc aaattgtgga gctaggcaaa atgtaagagc
    25741 tataaacaag ggtataaaat ttatttatga atttgatgaa aaaatggttt tatttgaatg
    25801 tgatgaaaaa aatatttcca aagcatttat gaatcttata gaaaatgctt tgagatacgc
    25861 taagagtgaa ataaaaatag tctgtaagca taaccaaaaa aatatagttg tgatagtaga
    25921 agatgatgga attggaatta agaaagaaga tttgcctcat gtttttgaaa gattttataa
    25981 gggagtaggg ggaaatcatg gaattggatt atcaatagtt aaatctatta taaataagca
    26041 tggtggacgt atatacgtag aaaatggcaa aaaaggagct aagtttacta tattatttaa
    26101 attgtaaaaa aattagagaa aatatagaga tgtttgaagt tgttttttat atatatctgt
    26161 tgtatactgt tgaaaaaaga acaatattaa gctgacatat attataataa ttgacattta
    26221 aagtaaatgc ttaaatatag atacgaaagg aaaagtaaaa tctgaagtgc atttaggttt
    26281 aagtaaactt cttattttat aaaaaatatg tatgaaagaa cagctgattt ttaatattac
    26341 aaatttagta acagttgtat ttgaagcttt tgtcatccat atgtttttat cagacttttt
    26401 aggtcagaaa gaagggtata taaaagttgt aagatatgct aaattgggtt ttataatatg
    26461 tttaggactt tgtaatttaa taactttaaa ccctaaaatt acaatgcctt taattttcat
    26521 tcttattttt tcaacatcat ttttatataa aggaaattta aagacacgat tgtttacgac
    26581 tgttttatta agtatatttt ttatactgtc agaaattgta gttacaagta tttttgtttt
    26641 atttataaaa gaaggctttg aaataatgtt tgaaaataat agtataagag tattggcgac
    26701 aattttatct aaaattgtct ttttgttgac ttgtaaaatt atttgtctat tcaaaaaaga
    26761 tgtacattta gatatgccca taaagtattg gtttccttta tttttaatac ctatatttag
    26821 tttatttctg tctgtttctg tctttgatgt aagtaaattt tttagtcttg aatgtttaaa
    26881 atttctgagc ttaatatcta gtattggtat tttgtatatt aattttattg tcttttattt
    26941 atttaaattt attatagata aaactaaact atctatgaaa tatgaaatac ttgaaaaaga
    27001 aataattcat aaggaagaat taagacttag taatgagcgt tataaaatta ttgttgaaca
    27061 gaccgattct gttgtttttg aatggaatat caaagaaaac aaatcgtttg tatcacaggc
    27121 ttggaatgaa aaatttggat ataataatgt atgtaagaat atttttaaag aaattaaaga
    27181 taaagactta gttcattctg aagataatgc tatatttgaa aattttcttg aaagtattaa
    27241 aaaaaagaat agacacaatc aagcagtata tcgtttaaaa aaatctaatg gtgaatatat
    27301 ttggtgtaga acatcaatta caagtattta taatgatgaa aatgagcttt taagagttgt
    27361 cggagtaatt gtagatgtag atagtgatat aaaaaaatat gaagagttaa aaactagagc
    27421 agaaagtgat tcattgacca atatatacaa taaaggtaca tttgaaaaat tggtagaaga
    27481 aactatagtt atgaatacag gtgataaaaa agatgcatta ttcatcattg atttagatga
    27541 ttttaaagaa ataaatgata attttggtca tccatttggt gattttgtac tgaaaacctt
    27601 tgctgataag atacaggcta gttttggtag tagagactta gtcggaagaa ttggtggaga
    27661 tgaatttgta gtatatatgc aagattacgt tacagaagta aatttgcaca aaaaagccaa
    27721 agagttaaat agagtacttt cggataatta cactgatttg agttttagtt ttgatgcttc
    27781 tgtcagtata ggtattgcaa ggtatcctca agatggaact tcattttttg aattgtttaa
    27841 aaatgcagat agagcacttt atagcataaa agcatcaggt aaaaattcat attgtttatt
    27901 tgaagaagag ctatatgtac agtgaattta gattttatgt gatatcaaga tttatatatg
    27961 cttgtggcat gtctaattta taaaatatgt tactatgtat gtttttatat gtttcagtga
    28021 ggttaattaa tataagcaaa ggtgtaagta aatttatatt aatgtaagtt tatttacacc
    28081 tttttaaaaa taaattttgt aaatttaaac agttaatttt ataattattt ttatttattt
    28141 taatatctta gctgttcctt tttgtattcc ttagagaaaa taaacaatga aaggagtaca
    28201 gaaaaaatta aacatcctaa tataatactt gaattaagac ttgaagcatt aaaatttaaa
    28261 aatgcattat ttaaatcggt atccaaaaga acagtattat taattaaatg aattactaca
    28321 catgaccata cgtttttagt tttcatatag acataaccaa agaatataga aagactaatc
    28381 acagaaaata atctaagtaa tatacctaaa acatctacat gataaactgt aaaccataat
    28441 ggtatgtgcc ataattccca tataatccct aataatataa cgcccattcg tttgccaaat
    28501 tttgtttgca ttttttcttg aagaaaacct ctccacccgt attcttctcc aaagaaaagg
    28561 atactttgat ttgctatata tggaaaaatt aaaaatatat tcataatcaa atttataaaa
    28621 ttaatatctt tccatcctaa cattatacat ttacttagat taattattat tataaaaata
    28681 aaaatacaaa taatagattt atttacattc ttaaatgggt aaagctcttt gccttctaaa
    28741 catgcataac atatcgttat aattccagta aataagacta aaatacccat tcctaagagt
    28801 atagtttcat catctattac tccaaatgct tttaaagtaa ctagaaatag agataataaa
    28861 aagtcagcta ttataacaca gtgaagtata atatgttcat cactcttttt atgtttataa
    28921 atctttgtta ttgcaactcc tgatgctggt aatatagtca taaatgttac cattatttgt
    28981 ggattcatat attttttaaa atatagaggt atcccaaata gaagtgatat accataagtt
    29041 actacaaaaa atattataac ttctaaagta tttatttttt tatcactatt tctatcagct
    29101 atttcgcatt gtatcataat aatttatctc ctttcagatt ttaacttctg ctgagatttg
    29161 agttagatat tcattagaat ctcgcacact tatatcatat agaagatatt cttcataaac
    29221 aaaatcccca atacataaat tattttgact aaaaaaattt aataactttt cataagtctt
    29281 gtaaatagtt tcataactac ctttatgata agcagttaca taaagccctt tttgcttgat
    29341 tgatacagga tatttcttgt actctttatt aacttttgta aataaatatg aatatgattc
    29401 aaaatcttta ttaattatat cttcaccttt aatgattgag ccaatcatac cataatcact
    29461 caattcatag ttgtctataa agttaataca ttcatataaa aaattttctt cctcatctcc
    29521 taaaaactgt tctttatatg taatgggcgt tttgaccaag tactcttctt catgttcttt
    29581 taaagtaata gtatttgcat ctatattaca ggcattttta gtaaatgaaa tagtagattc
    29641 cattagagct tgaatattat ttagtttttc aatttcattt ttaatatcaa tagttttctt
    29701 ttctaaaagt tcaattagta aattaggtgt tcttttgtct atataagttt taatttcttt
    29761 taaaggcatt tttatttcct taagtgaaga aattatacca aaaatgctaa gctgatggta
    29821 tgagtagtat ctatatccat tttctttctt taattctgga gagaaaagac ctatatcatc
    29881 ataatggaaa agtgtttttt tattgactcc acaaatcttt gcaaattctc cagttgtaaa
    29941 ataatttttt ggaacttgac tcataattat aattcctcct tgactatcct gttacagtat
    30001 agtttatcat aatattttgt aaaggagtgt gattgtatga aaaaattaat tcatttttta
    30061 aaaccatata gagttttaat tgttgtagtt ttgatattta cgtttttaca aacacttgga
    30121 actttgtata taccaacact tacagcaaat atagtaaaca atggcatagt aaagggagat
    30181 atagattata ttgtaaaaac aggtttaatg atgattatag tagctggtat aacagcttta
    30241 tcagctgtgt tagtttgtaa agtatcagca aatctttcat ctggattttg tagagatatt
    30301 agagaagcag tatttataaa atcacaagat ttatcaataa atgattttaa taatataggt
    30361 acagcatcaa tgattactag gagtactagt gacattactt taataggtca gtctgtattt
    30421 atgttcattc aattagtatt gccagcacca attataactg tttctggcct gttcttagct
    30481 tattctatag ataaagtaat gacaattatt attgttgttg taatgtttct attcatgtta
    30541 tcagcatttt tagttggtaa aaggcttatt agattgttta agattatgca aataaagatg
    30601 gataatatga atagggtatt gcgtgaggta gtaactggag taagagttat aagagctttt
    30661 aatagaagtc attttgaaaa aaagagattt gataaaactg caatagatta ttctgaaaca
    30721 gcaatttcaa taaataaagt attttcagta cttatgccta ttgtaatgtt aataatgaat
    30781 ttaggtatag taagtattat ttggtttggt ggtatgagag tcagtaatgg aaatatggag
    30841 ataggtcata taatggcact tgttgaatat tgtatattaa ttttattcta cttaatcatg
    30901 ggagtaatgg tatttatgta catacctaga gcaggtgcct gtgcagatag agtaaatcaa
    30961 atattagata tagaacctga aattgtagat ggaaatgtct acaaagatga tgtctcagaa
    31021 agaggacatt tagtatttaa aaatgtaacc ttttcatatg ctcaatcaga agaacctgtt
    31081 ttaaataata taacatttga agcaaagtct ggagaagtaa ctgcaattat aggaagcact
    31141 ggctcaggca aatctactat tgcaaatata ataccacgtt tttttgaaat tcaatctgga
    31201 gaaatctctc taaatggtca ggatattaag aagattcctc aaaaagaact tagagataag
    31261 attgggtttg taccacaaaa agctttttta tttagtggga caatagaaga aaatataagg
    31321 tatggaaaag aagatgcaag tattgaagaa gtaaagcatg ctgcaagtat agctcaagct
    31381 gatgaattta tttctgatat ggaagacaag tatgactcat ttgtagcaca aggtggaaat
    31441 aatttgtcag gtggtcaaaa acagagaata tccattgcaa gagcattagt tagaaagcct
    31501 gaagtatatg tctttgatga tagtttttct gcactagatt ttaagacaga taaaagactt
    31561 agaaaagcgt taaagaatga aatcaaagat tcatcagcta taattatagc acagcgtata
    31621 agtacaatca tggatgctaa tcaaattata gttttgaatg atggaaaaat tgtcggtatt
    31681 ggaaaacata aagatttact tgaaaattgt gaagtttata agcaaattgc agattcacaa
    31741 cttagtaaag aagagcttgc ataggatagg gaattaatct gtgtatttgg aggtgtgtaa
    31801 tatgagtgaa aaaagaacag ataaacaaga tatagaggta cttagttttg aagatggtat
    31861 gtcagcagaa aaagctaagg atgcaaaaaa aactactaag agattattaa aatatatggc
    31921 aaaacaaaag tttaaaatat taattatttt tatttcagta ttgataagtt cagcacttac
    31981 agttttagca cctatggtta tgggaaaagc tattgaccaa ctatttaatg gaataaaaac
    32041 tgcagtccaa acaggtacaa aattcagtgt gaattttagt actatgggag gtatagtatc
    32101 aatacttcta ggattgtact tggttagtgc aatatttata tatattcaac agtatattat
    32161 gtcaggagtt gcacaaaatt tagttcttag catgagaaaa gatttaagtg ataaactcaa
    32221 taaacttcct cttaagtact atgattctca taaaaagggg gaaacactta gtatagtaac
    32281 caatgattta gaaaaagtag cagatagttt acaagaagga ttaatgcaac ttattacagc
    32341 agtagttaca gtagttggtt ctattgtaat gatgataagt ataagtgtac cacttacaat
    32401 agtatcagct ataacattac ttgtttcatt gggtattact gttgtaattg caagaaaatc
    32461 acaagaaaga ttctctgaaa atcaaaaggc actaggagag ttaaatagca atatagaaga
    32521 gatatttact ggtcaaatag tggttaaagc atttagtaaa gaaaaggata ctataagaaa
    32581 ctttaaaata ttaaatcaaa atctttataa tgcaagtaga agagcacagt tttcgtcata
    32641 tgcaatatct ccaattatta gatttataaa cctaattggc tatgttatta tagcagttgt
    32701 aggtggtata tttgcatcaa ctggagcaat gactcttggt agtatacaag cgtttattca
    32761 atatgtaaat caagcatcag agcctactac agaaatatct tatattgtaa atatgcttca
    32821 agcagcaata gcatctgcag agagagtttt tacagttatg gacgaggtag aagaaataaa
    32881 ggatgaagaa tcttcaaagg ttatcagcat gcctagaggt aaagtacaat ttgagcatgt
    32941 taaatttgga tatagtgatg attttattct tatgaaagat attaatatca atttaaatgc
    33001 aggagataag attgcaattg ttgggcctac aggagctgga aagacaactc ttgtaaattt
    33061 acttatgaga ttttatgaga tacaaggtgg aagaattact attgatggtg ttaatataaa
    33121 agacttaaag cgtggagaac ttagaactat gtttggtatg gttcttcaag atacatggtt
    33181 gtttaatgga agtataaaag aaaatattgc atatagtaag tcagatgcaa caatggatga
    33241 aattgtaaga gcagcaaaat cagcaagagt agaccatttt ataaggactt taccacaagg
    33301 gtatgacact atattgactg aggatgcttc taatctatct caaggtcaaa agcaacttct
    33361 aacaattgcc agggcaatac tttcagaccc atcagtattg attcttgatg aagcaacatc
    33421 tagtgtagat actagaacag aggtagaaat tcaaaaggca atgaataact tgatgaaggg
    33481 aagaactagt tttgttattg cacatagatt atcaactatt cgagatgctg atttaatatt
    33541 agtaatgaaa gaaggcacta ttattgagca agggagtcat gaggaactta ttgaaaagaa
    33601 aggattctat gaagaacttt ataacagtca attttcaagt gaatatgatg aagatgttgt
    33661 atgattatca agttttaggc aactaaatga ttgataaata ttaagttaaa tacagtaaca
    33721 tataaggtta tatggaataa gagtatttct ctatttcata taaccttttt tatttgtcaa
    33781 aataagataa aatttccttt ctaaattaga ttgaagaatg tatttatcaa tataaaagta
    33841 aaataaccct taattagtga agtaaatatt gcttgccaca tatatgccat aaagatgcac
    33901 ttattttacg gagatttaac aaattagcat aaagtatact ctaaatatag aataaatcaa
    33961 atagagttaa ataaattgag aggtgatata aataatggat aaaaaattga actatagatt
    34021 tgaaatgaag cacaaaataa ctgaagcaga tgtgctagct ttaaaatcaa gactctatcc
    34081 aatcatgaag aaagataaaa atgcattaaa agatggaaag tatcttatta gaagtttata
    34141 ctttgatact cctgaggata aagctctttt ggataaattg aatggcgttg cattaagaga
    34201 aaagttcagg ataagatttt ataataatga ctgctcctat ataaggctag agaaaaaaat
    34261 caaacattac aatatgacat caaagctatc agctagttta actaagacag aagtgataaa
    34321 gatattgaac aatgatattg aatttctaaa agaatcgaca aattgtttat taagagaatt
    34381 ttatttgaaa ataaaatgtg aaagattaga ggcaaagagt atagttgatt atgatagaga
    34441 agcctttgtt tatccagttg gaaatgttag ggttacaatt gatagtgata ttaaaacttc
    34501 tgtaaattca atagatttgt ttaataaaca tttaccaact gtttcgataa ttgatgagaa
    34561 catgacggta cttgaggtta aatatgatga atttatacca gattttataa aggatttaat
    34621 tcaaattaat aagactactt ctacagcagt ttcaaagtat gcttcaagta gattatatat
    34681 ttaataataa aagctatgat ttatatgaag ctatacataa atgaggttaa aaaataaata
    34741 aaataaaaaa taaattaaag attaggaagg atgattttaa ttatgacatt taacgatatt
    34801 tttaaatcaa gttttataga aaacgtatca ggtttttcat ttgtggacag tgctttagca
    34861 ctaggttcag cctttttagt aggtttgttt atatatatgg tctataaaaa gacttatatg
    34921 gggattatgt attctcgacc atttaatgtg tcgcttgtag cacttacaat gcttacaacc
    34981 tttgtaatat tggcagttac ttcaaatgta gttttatctt taggtatggt tggtgcttta
    35041 tctatagtaa gatttagaac agcaattaaa gacccaatgg atttagtatt tctattttgg
    35101 tcattgggtt caggtatagt tttaggagca ggtttaattc cattagctgt catgggttca
    35161 ataattatgg gattgattct aatattcttt tcaaataaaa caatatctga aactccatat
    35221 atattgatgg taaactgtaa taatgaagat tcagaagata tagcaactga caaaattaaa
    35281 aaagcattta ctaaatatca aataaaatca aaaagtgtta caccagaaaa aggaatagaa
    35341 ttagtgtttg aaataagaat gaaagatgga gagacaagtc ttataaatga cttgagtcaa
    35401 gtagatggag ttactaatgc cgttcttgta agttataatg gtgactatgt agcatagaga
    35461 ggagtaatct tttatgaaag ataaaaaatt tacccttctt atctcaataa tgattatatt
    35521 tttatgtgct gtagttggaa tttatagtac atctggcaac aaaggtgttg atttatacag
    35581 tgatgtatat attgaaaaat attttaacag agacaaggtt atggaagtta atatagagat
    35641 agctgaaagt gatttaaaag acatgaatga aaatgctata aaagaagaat ttaaggttgc
    35701 aaaagtaact atagatggag atacatatgg aaatgtaggt ataagaacta aaggaaattc
    35761 aagtcttacg tctgtagtaa atagtgatag caatagatat agttataaga ttaattttga
    35821 taagtacaat actagtcaaa gtatggaagg gcttactcaa ttaaatctta ataactgcta
    35881 ttctgaccca tcttatatga gagagttttt aacatatagt atttgtgagg agatgggatt
    35941 gtccactcca gaatttgcat atgctaaagt atctataaat ggcgaatatc atggtttgta
    36001 tctggcagtg gaaggattaa aagaatctta tcttgaaaat aattttggag atgtaactgg
    36061 agacctatat aaatcagatg aaggaagttc gttacaatat aaaggagatg acccagaaaa
    36121 ctactcaaat ctaattgttg aaagtgataa aaagacagct gattggtcta aaataacaaa
    36181 actattaaaa tctttggata caggtgaaga tattgaaaaa tatcttgatg tagattctgt
    36241 ccttaaaaat atagcgataa atacagcttt attaaacctt gatagttatc aaggaagttt
    36301 tgcccataac tattatttat atgagcaaga tggggtattt tccatgttac catgggattt
    36361 taatatgtca tttggaggat ttagtggttt tggtggaggt agtcaatcta tagcaattga
    36421 cgagccgacg acaggtaatt tagaagacag acctctcata tcttcactat taaaaaatga
    36481 gacatacaaa acaaaatacc ataaatatct ggaagagata gtaactaaat acttagattc
    36541 agactatcta gagaatatga caacaaaatt gtataacctg atagcatcat atgtaaaaga
    36601 agacccaaca gcattttata cttatgagga gtttgaaaaa aatataacgt cttcaattga
    36661 agattctagt gataataagg gatttggtaa taaagggttt gacagaaata actctaataa
    36721 taattctgga aataaaagtg atgaaaaaga agttactgct gaattaacat taagtgaagt
    36781 caaaactaat atggataatg aaactgagaa taatactaca ggtgatagta aaaataagaa
    36841 taatacgaat gatgataaaa gtggaaatgg taataatcaa aagccagaag gttctatggg
    36901 taaaggagga aagtcaatac caggagtttt ggaagttgca aaagatatga gtaaaactat
    36961 aaaagctcaa ttaaatggag aaacttcttc aacaaagcaa aattctggtg atgaaagctc
    37021 aagtgaaaat aaagggactg aaaagtttga tgaggatgtg ggtggtatgc cagaaccacc
    37081 tgagggaatg gatggtaaaa tgccaccagg aatgggaaat atggataacg gtgatatgaa
    37141 tggtaaaaat ggcaatatga atagaaatca aggtaatcca agagaagctg gaggttttga
    37201 aaataaagga gggggctcta tgagtaaaac aagaacatac tcaaaattaa ttttaggtgg
    37261 agcttcaatg ataattatgt tgattatgtt agtaggtgta tcaaatataa atagaagaag
    37321 atttataaag tcaaaataag attgatatta aaaaatactg ttgagtagac atctactcaa
    37381 cagtattttt tagatattaa gattaaattt atttagaaat aagagttaga tttttttact
    37441 taaattgaaa taaaatatgc aaatagtttt aaaatgtaga aattatttat
//
LOCUS       DAMKOJ010000036        37427 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000036 DAMKOJ010000000
VERSION     DAMKOJ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37427
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.038"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            80..421
                     /locus_tag="PC592_001922"
     CDS             80..421
                     /locus_tag="PC592_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HDF4055897.1"
                     /translation="MKEENFINIEYEDKRFSINSKEVLYIEKQEYEVKIYTENGNYEV
                     GENAPCIRKLMKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            572..985
                     /locus_tag="PC592_001923"
     CDS             572..985
                     /locus_tag="PC592_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HDF4055898.1"
                     /translation="MLELKNNSGTSERKLKYPCIYKHFKGKYYATMGLSKAIDNVENI
                     CEIYSKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFGRPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1185..1826
                     /locus_tag="PC592_001924"
     CDS             1185..1826
                     /locus_tag="PC592_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF4055899.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILADKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIIKMNDTSHIKNHVKINNSALE"
     gene            1850..3103
                     /locus_tag="PC592_001925"
     CDS             1850..3103
                     /locus_tag="PC592_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF4055900.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNRDIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEALNKDLLNHNVKIIYNKKVIDIITEEIAIKDDSNKNKSKYLIKGI
                     ILDNGDKILGDKIIISTGGVSYSKTGSDGLMYKILKNHGHTLNKLYPALVPLTIEEKW
                     IKNLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSSDEISSIIREFPNKNVLNNLKQILPQNFLKEILSLLSLSDKKASDLSK
                     ADEIKIIEYIKNMKLTCTGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3149..3799
                     /locus_tag="PC592_001926"
     CDS             3149..3799
                     /locus_tag="PC592_001926"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDF4055901.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGVDVNNEKEVIQIAENSDIDFKDNSIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVQVQRKIGMKSSVILDGRDIGSYVFPNADYKFFLVATPEERGNRRYKELCDKG
                     YNTTLKAVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVISKINL"
     gene            3850..4446
                     /locus_tag="PC592_001927"
     CDS             3850..4446
                     /locus_tag="PC592_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF4055902.1"
                     /translation="MNFYKFVINIFKGFTRIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAVENREIAAIAKKELFKVKPLGFILKKMHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLTNDDHERISQEILEVIKQNYFKYSK"
     gene            4459..5298
                     /locus_tag="PC592_001928"
     CDS             4459..5298
                     /locus_tag="PC592_001928"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDF4055903.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKSDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKNKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVNVCEELVPTFAIETKDELDVNMLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5551..6705
                     /locus_tag="PC592_001929"
     CDS             5551..6705
                     /locus_tag="PC592_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HDF4055904.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDTSKNNSKENKEKHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIILIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMVITTIPAIIVGMIVYAFLG"
     gene            7004..8701
                     /gene="ade"
                     /locus_tag="PC592_001930"
     CDS             7004..8701
                     /gene="ade"
                     /locus_tag="PC592_001930"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDF4055905.1"
                     /translation="MGNLKKQCDVASGREKADIVLKNGTIINVFTEELIVGDVAIVGD
                     TIVGIGDYKGTVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMIPSSVPATSFETNGIGEFSAKDMESYINN
                     PRILGLGEVMCFNDVINSDNNILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVNGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPIRAIKVATYNSARAYGLKRIGAIGAGYKADIVVLNDLE
                     KMEVDSVYKDGNLVKEEMFSNYNYDIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKLYESLPCVEGYFIPSEEYSKLCVVERHRMTGNIAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDIIVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTLT
                     AKEVQETTDNMLEIARKMGVPKYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            8943..9401
                     /gene="bcp"
                     /locus_tag="PC592_001931"
     CDS             8943..9401
                     /gene="bcp"
                     /locus_tag="PC592_001931"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDF4055906.1"
                     /translation="MLSIGTRAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDVQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEK"
     gene            9417..10160
                     /gene="yaaA"
                     /locus_tag="PC592_001932"
     CDS             9417..10160
                     /gene="yaaA"
                     /locus_tag="PC592_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDF4055907.1"
                     /translation="MIIMLSPAKNMKNIEVSDRDLSLPCFIDNTKEIVENINTFSVED
                     FKKKMKINEKLAILNKNRFESIKFDKLGSPAILTYDGIQYKNIEAENFTRQDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQAKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGIFKVESTQAKKARGMMTKYIIKNRIRD
                     IEELKKFNLEGYKYQENLSNNSEYIFVKE"
     gene            10288..12948
                     /locus_tag="PC592_001933"
     CDS             10288..12948
                     /locus_tag="PC592_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF4055908.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPNRTTLQMLWSQITDAMVLILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKEYVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     NTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMSKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEILEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITELDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGIVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTISYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSALLIAVILFVPVFRNAFNLTILNSL
                     EWLITIALAIMSVVQVEVGKIIKRKKLKNS"
     regulatory      12998..13100
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            13208..14473
                     /locus_tag="PC592_001934"
     CDS             13208..14473
                     /locus_tag="PC592_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HDF4055909.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVASVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENAFKIAKFLEKHENVDWINYPGLEDNKYYENAKKYLSKG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            14503..15393
                     /gene="metA"
                     /locus_tag="PC592_001935"
     CDS             14503..15393
                     /gene="metA"
                     /locus_tag="PC592_001935"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDF4055910.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKKLTYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKSKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKNSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINRGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            15687..16130
                     /locus_tag="PC592_001936"
     CDS             15687..16130
                     /locus_tag="PC592_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4055911.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLTKFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQENISSSIFDNYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            16160..17977
                     /gene="ftsH"
                     /locus_tag="PC592_001937"
     CDS             16160..17977
                     /gene="ftsH"
                     /locus_tag="PC592_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF4055912.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLNILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALSEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKTCH
                     KNAIEILENNIDKLHELAKYLLEKETITGDEFMEILNLN"
     gene            18155..20857
                     /locus_tag="PC592_001938"
     CDS             18155..20857
                     /locus_tag="PC592_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDF4055913.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYASGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKKFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     VSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETASKREENTKMIYQIIKGFLRLSNKDDIINKGIELLSLSLSRDVICYLNVDKYNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCVDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVEDNKDKGSTFKFSLPKENE"
     gene            20891..21589
                     /locus_tag="PC592_001939"
     CDS             20891..21589
                     /locus_tag="PC592_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055914.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEVQQKDDVKSTFEVDKLLIDFDKRKVIVDDIEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            21946..22902
                     /locus_tag="PC592_001940"
     CDS             21946..22902
                     /locus_tag="PC592_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HDF4055915.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYSFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            23364..24377
                     /gene="aroF"
                     /locus_tag="PC592_001941"
     CDS             23364..24377
                     /gene="aroF"
                     /locus_tag="PC592_001941"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF4055916.1"
                     /translation="MIVVLKIGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKIVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEEQIVSIAEDVKKSGAGFLRGGAFKPRTSPYAFQGLRYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            24399..25463
                     /locus_tag="PC592_001942"
     CDS             24399..25463
                     /locus_tag="PC592_001942"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDF4055917.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILNNVGEEIKRIYFGNKIFIVTD
                     ENVAKLYLDKLKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGINFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKHYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVEAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            25463..26776
                     /gene="aroA"
                     /locus_tag="PC592_001943"
     CDS             25463..26776
                     /gene="aroA"
                     /locus_tag="PC592_001943"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDF4055918.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSIAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFNRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTMKDFGIEI
                     INNNYKEFIIKGSQTYKARDYKVEGDYSQGAFYLSADAIGEDINILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNSTLIDASQCPDIIPVLSVVAALSRGKTTIIN
                     AGRLRIKECDRLHAINIELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFEMLGGRIDEWNMGK"
     gene            26754..27833
                     /gene="aroC"
                     /locus_tag="PC592_001944"
     CDS             26754..27833
                     /gene="aroC"
                     /locus_tag="PC592_001944"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDF4055919.1"
                     /translation="MSGIWGNNLKISIFGESHGNAIGINIDGLPSGVELDLEKIDREM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEVGAHIKKIK
                     NIEDMSFNYVNISKQQLSNLQTLELPLLDLSKEEKMKNTIIDAKNQRDSVGGIIECAV
                     VGVNVGFGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKEKKDDILSIKGRHDP
                     CIVQRVIPVIEAVTAIGIFDLMKGR"
     gene            27836..29032
                     /gene="pheA"
                     /locus_tag="PC592_001945"
     CDS             27836..29032
                     /gene="pheA"
                     /locus_tag="PC592_001945"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDF4055920.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETIQFFNSIMEISRGLQKRLMDNDSEQKIEFRLDS
                     SKKKFDLSSVNKYKSLKEELNKKNILVGFPGKSGSFTEEALNKFFNKKTAKKQFKEFE
                     DVFIALKNKKIDYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLKDIKEIYSHPQGIGQCSEFLKQNSAWKLIPFNNTATSAELVKKLQDKTKAAIASKK
                     AASIYGLEIISPCINDITNNYTRFVVISNQIHIEEESNKMSVVFSVEHKAGKLYKVLG
                     YFAENNINMTKIESRPMKNTSWRYFFYIDFECSIYNSKVYNLLELIELNTAYFKFMGV
                     YKNKTK"
     gene            29072..29881
                     /gene="aroE"
                     /locus_tag="PC592_001946"
     CDS             29072..29881
                     /gene="aroE"
                     /locus_tag="PC592_001946"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF4055921.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDVS
                     KLASAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLREDMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAAITYLLDSGIEKVYVSTRKKDDKKLLNS
                     KAILVDYEELKCITGDIILNATPVGMYPNVGISPVSKSIIQNFDTLVDLIYNPGETEF
                     LRIGNSIGKKTCDGLYMLVGQAIKSQEIWQNAKIDNSILDVIYNELKLEFL"
     gene            29893..30426
                     /locus_tag="PC592_001947"
     CDS             29893..30426
                     /locus_tag="PC592_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDF4055922.1"
                     /translation="MTNKTKEKLILIGMPGSGKTTIGKLLAREYNCSFCDMDDYIVKI
                     AQKSIAELFSEGEDIFRNYETQACRELSISNKAVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNTAVY
                     NIINAVSEKFKFEFKEK"
     gene            30447..31286
                     /locus_tag="PC592_001948"
     CDS             30447..31286
                     /locus_tag="PC592_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDF4055923.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKRGIDFASEQVFNGANYIITPTGRNNIRNLELVENLI
                     LKLGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEDRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLIKEAIFNNDKSKLIEYFKKSSIRREI
                     LEK"
     gene            31565..33034
                     /locus_tag="PC592_001949"
     CDS             31565..33034
                     /locus_tag="PC592_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF4055924.1"
                     /translation="MLIVRNVSIAFIVLFFFSVFAFFYVANINRVLEYETNNLMTITI
                     TGWIILSFLFLGIIIYILYSKAKSQKTIEKVAYTDFVTGYSNWRKFELDVTNLLKKTS
                     QNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELININETFARVSADNFNI
                     LLTYNKKEDIINIIKKIMVNNELVNLSFGIYEIKDKALSVSVYSDRASLAKSSIKNNS
                     DVNFAFFNDELREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLNKFCGSEALVRW
                     QYTEKEVIYPGDFIPVFEKNRFIRKIDMYILEQACKEIRSLFDKGISPLPISVNFSRV
                     DFLKKDFISNIVNVCDRYKIPYGLIEIEITESSMFGDTDILFNVSRNLQDIGFIVAMD
                     DFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRVVAEG
                     IETKSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            33067..36504
                     /locus_tag="PC592_001950"
     CDS             33067..36504
                     /locus_tag="PC592_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF4055925.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSMANMVSYFNTIDNSKIIPLLANISKESDFQRISIV
                     SPDGISHTSDGKIIDVSNYQYFKKAISGESNISEVVKSPIDGKDTFVIATPIFNKNNK
                     IIGILYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYKDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIILIIYIIYKNNKSQRDILKANKEISSITNSIPGG
                     VQKCTLGETCKINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEISKQL
                     YKNKTIELEYRIITKSGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENILGGILITELNEDFTIKYTNSGYLSMIGYTREQLENELKYKACDLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITENV
                     PYSLVESGVIHKDFSNDFINMYEKVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNENW
                     QKPFGIKPDNNYSQMAKTIANSIVHKENKEVFLNTFLCENLLDAYKNNITEIKLEYQR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEKASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKHLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENAKKKAEKICDIFRNSYTKNKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKVANK
                     CEKSNPVLKEVLDSIDNYIYIVNPNTYELLFVNNKVSRSGLEIKLGQTCYKSLLKSDR
                     PCSNCPLNGLEENKHSKFKIETNTFGTNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            36521..37267
                     /locus_tag="PC592_001951"
     CDS             36521..37267
                     /locus_tag="PC592_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDF4055926.1"
                     /translation="MLNGITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIILIIYQ
                     IFKKKIKEKKVFYRVLKIIISVFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TIPSTTLKGRLNTALKYLKVNDNCYVVVSGGKGSGENITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKFKIEERSERKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIFFDR"
BASE COUNT        15215 a         3860 c         6542 g        11810 t
ORIGIN      
        1 agtcttacat atatttccga tagattatat tgataaaaaa cactaaaatt aaattaataa
       61 agtacttgga gggatggaaa tgaaagagga aaattttatt aatattgaat acgaggataa
      121 acgtttttca attaatagta aagaagtttt gtacatagaa aagcaagaat atgaagtaaa
      181 gatttacaca gaaaatggta attatgaagt tggagaaaat gctccttgta taagaaaact
      241 aatgaaagaa gaaaattttt tcaaatgtag taatagttat attgtaaatt tagataagtg
      301 tgaattttat ctcagcaata attgtatttt tgtgaataat aattttataa gaattttagg
      361 ttcagaaaga aaaaagaagt taaaaaagaa attagaaaaa ttatatgatt atgaagatta
      421 atattgagag gctgtatttt atacagcctc tttatttatt cattgtatta ttaataaatt
      481 ttaaattatg ataaaatata aaacaagtaa cttatttcag aaaaaaatac tttttaaaag
      541 aaagggacga gatatgggag attataataa aatgcttgaa ttaaagaata attcaggtac
      601 tagtgaaaga aaattaaaat atccttgtat ctataaacat ttcaaaggga aatattatgc
      661 tacaatgggt cttagcaaag ctattgataa tgtagaaaac atatgtgaaa tatatagtaa
      721 agaaaattta atccaaaata gaaataaata taaattagtt attagacata ctgaaagaga
      781 agaagatatc tatgtctata gagatttaga tggaaacttt tatcataaaa aagaagaaga
      841 taccaatgat ttagttttat acaagacttt atatgacgat acaggaatat ttggaagacc
      901 tttggatatg tttttagaaa aagtagatac agataagtat gtcaattcaa ttcaagagta
      961 cagatttgaa gaagtatata aataatataa gagaaatatg tttataaatt tagaaaaatt
     1021 atttaagagt ataataattt gcagaaatac aaatgagatt tattgtaaac aatatgttag
     1081 attggattat aaaatagaaa caaagtaaag tattatatga tataattaag ttttgagaag
     1141 tgatattata tttaataaaa aataggcata tattaggagg acatatggga aatacttttt
     1201 atatagtaag acatggacaa acagattgga atatattagg aaaaacacaa gggcatggta
     1261 attctgacct tacacctcaa ggtatagaac aggcaaaaga actttctgaa gatattggca
     1321 agtattcaat tgattatatt tttagtagtg accttggaag agcaatgcaa acagctcaaa
     1381 ttttagcaga taagctcaat attgaagttc aaaaaactga agcacttaga gaaatgggat
     1441 tcggagtttg ggaaggtctt ttaataaaag aaattcaaaa ggattattca gatatatatg
     1501 caacatggag aaatgagcca catttagtaa atataccaga aggcgaaacg cttaaaatta
     1561 taaaagaaag agtagatgct tttataaagg aattaaatga aaagtacgat aataaaaata
     1621 taattcttgt tacacattca attacattga gggttatgtt gttgtcattt ttagaatcag
     1681 ggatggaaaa tatatataga attaagcagg ataacactgc tttaaacata gtagaattta
     1741 aagattacgg acctgttata ataaaaatga atgatacaag tcatataaaa aatcatgtaa
     1801 aaataaataa ttctgcattg gagtaggaat caattataag gagaaattta tgagtaaagt
     1861 tatagtagtt ggtggaggag cttctggaat gatggcagct ttgtcagctt caaaaaataa
     1921 taatgaagta atattagttg agagaaatgg agaattagga agaaaactga gagcaactgg
     1981 tggaggtaga tgcaatttta ccaataacag agatatagaa gatttttttg ataaagtcgt
     2041 tagcaataaa aaatttctct atagtagttt ctatacattt acaaataaag accttatttc
     2101 atattttgaa agtagaaatt tggaatataa gattgaagaa gaaaatgacc acaaagtata
     2161 tactaaaaat gataaatcta tagaggtaat agaagcatta aataaagatt tactcaatca
     2221 caatgtaaaa ataatatata ataaaaaagt tatagatatt ataactgaag aaattgctat
     2281 aaaagatgat tctaataaga acaagtcaaa gtatctaata aaagggatta ttttagataa
     2341 tggagacaag atactaggag acaagattat tatatcaact ggaggagtga gttattcaaa
     2401 aacgggttca gatggtttaa tgtacaagat tcttaaaaat catggacata cattaaataa
     2461 actatatcct gctttagttc cacttacaat agaggaaaaa tggattaaaa atttgcaagg
     2521 aatatccatg aagaatgtgg aaatatcttg taagattaag aaaaggaaaa tatcaaaatc
     2581 gggagacatg ttatttgcac attttggaat aacaggacct tgtgtgctta taatgtcttc
     2641 ttatattaat aagattattg aaaaagaaaa ggtagaatta aatatagatt ttttaccaaa
     2701 tttaagtagt gatgaaattt ctagtataat cagagaattt ccaaataaaa atgttctaaa
     2761 taatcttaag caaatactac ctcaaaattt cttaaaagaa attctatctc tattatcttt
     2821 gagtgataaa aaggcaagtg atttgtctaa ggcagatgaa attaaaatta ttgagtatat
     2881 aaagaatatg aagctaactt gcactggaac tacaggtata aacactggta tggttacttc
     2941 tggtggtatt tcagttaaag aaattaattc ttctactatg gaatctaaat tagttaagaa
     3001 cttatttttt acaggggaag taattgatat agatgcagaa actggtggat acaatttaca
     3061 aatagcattt tcaactggat atcttgcggg tattagtgta taaatataat tttttaataa
     3121 ttaaatatga ataaatagag gtgtatatat gggtaattta gttatagctg tagatggtcc
     3181 agcaggagct ggaaaaagta caatagccaa gatagtagca aaaaagctaa atataaatta
     3241 tatagataca ggtgctatgt acagagcagt tacttataag tgtttaaaaa gtggggttga
     3301 tgtcaataat gaaaaagaag ttattcaaat agctgaaaat tcggatatag atttcaaaga
     3361 taatagtata tatttggaca aagaagttat aaatgaagaa ataagaacga tagaagtaag
     3421 taataatgtt tctaatgtgg caaaaataaa agaagtaaga cagttgatgg ttcaagttca
     3481 acgaaaaata ggaatgaaaa gttcagtaat actagatggt agagatatag gttcatatgt
     3541 tttcccaaat gcagattaca aattcttttt agtagctact ccagaagaaa gaggaaatag
     3601 acgctataaa gagctttgtg ataaaggata taatactact ttaaaagcag taattgaaga
     3661 tataataaga cgagatgaaa ttgattcaaa tagagaattt gcaccattag taaaagctaa
     3721 tgatgcacta gaaatagata ctacaggaaa aaccatagaa gaagttgtag aagaagttat
     3781 atctaaaata aatctttagt tttttatgta ttataataaa aataaatgta gtgttgaagg
     3841 gagataaacg tgaattttta taaatttgta ataaatattt ttaaaggttt tactagaata
     3901 ttttttaaat atgaagttat aggtgcagaa aatattccag atagagggaa tatagtaata
     3961 gcatcaaacc ataaatcgaa tctggaccct atattcttag ctgctgccgt agaaaataga
     4021 gaaatagctg caattgcaaa gaaagaattg tttaaagtaa aaccattagg atttatatta
     4081 aaaaaaatgc atgttatgcc tataaataga gaaaagccag atgtatctac aataaaaact
     4141 attttaaggt cagttagaga tggttatgtg ttaggcatat ttccagaggg tactagaata
     4201 aagggagatt cttttggtaa ggctaaggca ggtctttctg tatttacaat aaaaagtaaa
     4261 tctaaagttg ttccagtatc aataatatcc aaatacaaac tttttagtaa agtaattgta
     4321 tatattggag aaccaatatc atttgaagaa cattttaagg aaaaattgac taatgatgac
     4381 catgaaagga tatcacagga gattttagag gtcataaaac aaaattactt taaatattca
     4441 aaataagggg gtaaatttat gaacataaaa atagcaaaaa atgctggatt ttgttttgga
     4501 gtaaaaagag caatgaaaat ggcatgggat gaagttgaaa aaagtgattc tggcatatat
     4561 gctttaggtc ctcttattca taacaagcaa gcagtagcaa aatatgaaga aaaaggtctt
     4621 aagactgtga atgaaattga tacaatacca aatcatgaaa atatgataat aaggtctcat
     4681 ggagttcctg aaaatatata taaagaagct aagaacaaaa aattaaaaat tgtggacact
     4741 acatgtccat ttgtaaagaa aatacataca gtagtaagtg aatatcataa taaaggctat
     4801 gagataatag ttattggaga tatgaaacat ccagaagtta taggtataaa tggatggtgt
     4861 gaaaattcag ctataataat aaagacttta gaacaaatgg aaaatatgga atttgataac
     4921 tcaaaaaaat attgccttgt tgcacagact acaataaatc cagagttgta tataagtata
     4981 gttaataaac tatcagataa attagaagaa atagtattta atgatacaat ttgttcagct
     5041 acaaaaacaa gacaagagtc agctaaggag ttagctaaag aagttgattg tatgatagtt
     5101 ataggaggca aacacagctc aaatactcag aagttagtaa atgtttgtga agagttagta
     5161 ccaacttttg caatagagac taaggatgaa ttggatgtaa atatgcttaa aaaatataaa
     5221 aatttaggta ttacagcagg agcatctaca cctaattgga taatagaaga agttgtaaca
     5281 ttccttgaaa atttataaat ttgatagata ataaaaatag gtggatatta ttataacata
     5341 aaacttatta taatatctgc ctttgatttc atattacatg tggcaaatag ataacctaat
     5401 attaaaaagt gtgtatctta agatgaaaaa ctaatagtat aagatgcgca ctttttaata
     5461 ttagaaattt aaaataaata ttgatattga ttatcaatag aaaatggaat ataatataat
     5521 tattgcaaaa ttagtctagg aggtaaatta atggaaatgt taatatccgc ttctgaagag
     5581 gcgtttttac atgtaggttc tatgattgga ttttttattt tgttatttgg atatattaat
     5641 tataaaacta gtggaaattt tactaatatt atatcaaaaa acagaaaatt tcaaccttta
     5701 ataggtgctt taattggagc tataccaggt tgtgggggaa gtttggcaat aatgccattg
     5761 tatataaatg gaaaattaag ctttggagca ataattgcaa gtttaatagc tagtatggga
     5821 gacgctgcat ttgtacttat ttcatcaaat attaaaatgt atttttttgt cactatagtt
     5881 agtactatta caggaataat aactggacaa ttagtggatt actttaaact agaagaaaaa
     5941 ttaggtctaa aaaaccgtag aaaatcggat aaatacgata caagtaaaaa taactctaaa
     6001 gaaaataaag aaaaacataa tcatgatgaa ataattttgg atactctggc taaatctcat
     6061 ggaaatacaa atagacttgc attcataata acacatggaa agggatataa aatttatata
     6121 ggaattatat taatcggttt tatatttatg tcacttgctc actctggact taatcttcct
     6181 ataattgaga agttacattc attggaagaa gtaatagcag tgattggaat attattttca
     6241 ataatttata tgtggtgttt taaaaaggta tttaaaaatt ctaatcagaa agaggaagaa
     6301 aataaaaaga tttctttacg agaaatgctg atacattctg ttggcgaaat atcatttgta
     6361 attacatgga tttttattgc ataccttatt tacgatttga taatattaat tttaggtgga
     6421 gatgaatatt tagttaaact agtattatca acaggtgtaa taagtgtatt tataggtgca
     6481 ggtcttgggc ttattccagg ttgtggtata cagattgtac ttatgtcatt ttatttgaag
     6541 ggaactatac cacttggggc agtgatagcc aactctattt ctcaagatgg agatgcactt
     6601 ttcccacttt tagcaatgga taaaaaatct tctttatggg ctatggttat tactactata
     6661 ccagcaataa ttgtaggaat gatagtttat gcatttttag gttaaatata aataaaaaag
     6721 tattaaaaaa ttaataaatc acataaattt atttgcaaga atagtaaact taaatatata
     6781 aataaaaaat tcaatataac ttaaattatt acttaaatat taatgagaac atgggagata
     6841 atattattcc ttatgttctc tctatttaat taaatgaatt atggaacaaa tttcaagtga
     6901 tactttttat taaaactcat atataatata tattaataaa ttaaactata atatgtaata
     6961 cagccagtat attgatataa aaaacttaag aggagttgta aaaatgggta atttaaaaaa
     7021 acagtgtgat gttgcaagtg gaagagaaaa agctgacatt gtacttaaaa atgggacaat
     7081 cataaacgta tttacagaag agctaatagt aggagatgta gcaatagtag gagatactat
     7141 tgttggtatt ggcgattaca aaggtactgt agaaattgat tgtagcaaca aatatatatc
     7201 acctggtttt attgatgcac atatgcatat tgaatctaca atggtaatgc caattgaatt
     7261 atcaaaaaaa ttattaaaat caggtacgac aaccatcata gccgacccac atgagttggt
     7321 aaatgtaaaa ggagctagtg caatagattt tttattagaa tcgacaaaag atataccact
     7381 taatgtatat attatgatac cttcatccgt acctgcaaca agttttgaaa ctaatggaat
     7441 tggtgaattt agtgcaaaag acatggagag ttacataaat aatcctagaa ttttaggctt
     7501 aggagaggta atgtgcttta atgatgttat aaattctgat aataatatct tggataaact
     7561 agagcttttt aaaaataaag ttgtagacgg acatgcacct aatataaatg gtaaatcgct
     7621 tcagacatat gtatgcgcag gaatagaaaa tgaccatgaa tgtataactt ttgatgaagt
     7681 atatgaaaaa ttgagagcag gtttaaaaat attaataaga gaaggaagtg cagcaaaaaa
     7741 tttaaaatct atagtaaatg gtatgctaaa gcataacttg ccaattgaag agtttatgtt
     7801 ttgcacagat gataagcact tagatgatat agaaaaacaa ggtcacataa gatggaatat
     7861 aaaatgtgcg attgatttag gtatggaacc tattagagct ataaaagttg caacttataa
     7921 ttctgcaaga gcatatgggc taaaaagaat tggagcaata ggtgctggtt ataaggcaga
     7981 tattgttgta ttgaatgatt tagaaaaaat ggaagtggat agtgtatata aagatggtaa
     8041 tttggtaaag gaagagatgt tttctaatta caattatgac attaaagata aagaattgct
     8101 taatacagtc aaatttaaat atattaataa ggaaaaaata cagttaaaag taagtgaaaa
     8161 aaattatgta atggagattg taccttatca aattttgaca aataagttat atgaatcatt
     8221 accatgtgta gagggatact ttattccaag tgaagagtat tcaaaacttt gtgttgttga
     8281 gagacataga atgactggaa atatagcaat tgctccacta aaaggatttg gcataaaaaa
     8341 tggagcaatt gctactactg tggctcatga ttctcataat attatagttg caggggataa
     8401 cgatgatgac attatagttg ccataaatta cttaaaggaa atacagggtg gttatgtaat
     8461 tgtatcaaat ggaaaagttc ttgcacacct aagtcttcaa gtggctggat taattagtac
     8521 tcttacagcc aaagaagtac aagaaactac tgataatatg ttggagatag caagaaaaat
     8581 gggagttcca aagtacgtag acccttttat tacactttct tttatggcac ttccagttgt
     8641 tccacaaata agacttacag atttaggtct atttgatgtt gaggaattta aatttatata
     8701 ggcaccataa taataaatta ggatattcaa aaatagagat tgtactacac cccaattgtt
     8761 ggactaaaaa cctaatgatt ggggtgttta tatataacta aatacaatgc atataaatac
     8821 atgaaaatta tatatttatg aaactttata cataaaaaat aaaatatttt atttatatat
     8881 agatttatag ggtaataata taagcatagt atagaattat caataaaaaa ggagagatat
     8941 ttatgttgag tataggaaca agagcaccag aatttacact agaagacaaa gatggaaata
     9001 aggtaagtat gtcagatttt aaaggtaaaa aagtagtagt atatttttat cctaaagata
     9061 atacaccagg atgtacacgt caagcttgtg cttttagaaa tgcgtatgat ggatttaaaa
     9121 aggaggatgt acaagttatt ggtataagta aagatagtat aaaatcacat caaaaatttg
     9181 cagaaaagca tgaacttcct tttattttac tttctgaccc tgatttagtc gctataaaag
     9241 cctttgatgt atggaaagag aaaaaaatgt atggaaaaac tgcattggga gttgtacgtg
     9301 cgacatatat catagatgaa aatggaatta ttgaaaaagt ttttgaaaaa gcaaaaccag
     9361 acacaaatgc acaagagatt cttgaatatt tggaaaaata ggagcaataa gaatttatga
     9421 ttataatgtt atcaccagct aaaaatatga agaatataga agtgtctgat agagatttga
     9481 gtttgccctg ttttatagat aatacaaaag aaatagtgga aaatataaat acatttagtg
     9541 tagaagattt taaaaagaaa atgaaaatta atgaaaaatt agctatacta aataaaaata
     9601 gatttgaaag tattaagttc gataaattag gaagtcctgc aatcttaact tatgatggaa
     9661 tacaatataa gaatatagaa gcagaaaatt ttacaaggca agatgaagag tttgcaaata
     9721 gttgtattcg aatcataagt ggattgtatg gagttgtaaa accatatgat agtatatatg
     9781 aatatagatt agaaatgcag gcaaaattac gagtaggtga gtttaagaat ttatacgaat
     9841 attggggaaa tcgtatatat aaagaactaa ttaaagaaaa aacagctatt gtaaatcttt
     9901 catcaaatga atacagcaag tccatagaaa aatttattaa agatagtgat acatatatta
     9961 catgtacttt taaagtaaat aaaaatggta tatttaaagt ggaatctaca caagcaaaga
    10021 aagctagagg tatgatgaca aagtacatta taaaaaatcg gataagagac attgaagaac
    10081 tgaagaagtt taatttagaa gggtataagt atcaagaaaa cttatctaac aatagtgaat
    10141 acatatttgt aaaagagtag aaattttatt aaatgttaaa tgacattgtt aaatttaggt
    10201 aaaatatact tagtgtgtat tgaattgaac ttgattttaa aatataatta ttcttaaatc
    10261 aaaaaaagaa aggagtggtc ttccaaaatg gaaaatcaca aacagatgcc ttggcattca
    10321 agagcaactc atgaaatttt agaaagtcta gattcatcag aggaggggct caccgatacc
    10381 gaggcggaaa aacggcttaa agagaatggt ttaaatgaac ttagaaaaaa accaaataga
    10441 acaactttgc aaatgctttg gagtcaaatt acagatgcta tggttctgat actaatagga
    10501 gcagcaatat tgtccttgat atttggagaa tttacagaag cttttgtaat actaataatt
    10561 gtaacagtaa atgcagttat tggaattgtt caagagaaaa aggcagaatc atcattagaa
    10621 gcattaaaaa atatgaactc accaacagct cgtgttatgc gtgatggtga agaaaatgtt
    10681 attccagcaa gtaatcttgt agtaggagat attgtttttt tagaagatgg agcgatggtt
    10741 ccagcagacc ttcgtttgat agaaacatct agtttaaaaa ttcaagaggc ttctttaaca
    10801 ggagaatctg ttccatcaga aaaagatgca gatacaatct tacctaaaga atatgtatta
    10861 ggagaccgta gcaatatggc gtatacatct tcaattgtca catatggtag aggtgtaggt
    10921 gttgtagtag caactggtat gaatacagaa gtgggtaaca tagcacatct tttagattca
    10981 caagatgatt ttgatactcc tataaaacgt aaacttaata ctgttggaaa gacattaagt
    11041 gtaataggta ttattgtatg cgttgttata tttgcaatag gtgcatttta tcagagacct
    11101 ctcttgccaa tgtttatgat tgcaatttcc cttgccatat caattattcc agagggatta
    11161 cctgcaacag ctactattgt aatggcttta ggcgtacaac gtatgtctaa aagaaatgct
    11221 ttaattagaa aattacctgc tgttgaaaca ttaggaggag ctacagtaat atgttgtgat
    11281 aaaactggta cattaacctt aaataaaatg actgttacac atattgctgt caatggagat
    11341 tttgaatctg ggaaagtaac atcaatagat actgcatctg aaaaacatcc gttagtgtat
    11401 aaagagattg tttatgctgg tgcactttgt aatgatgcat gcattaatcc agataaaact
    11461 gatgaaatat taggtgaccc aacagagggt gcattaattt ttatggccaa aaaatttgga
    11521 atagatcagg aaattcttga agaagaatat ccacgtgtat ttgaacagcc ttttgattct
    11581 gatagaaaat gtatgacaac tgttcataat atagatgaaa agattattgc ttatactaaa
    11641 ggagcagtag acgaaattct tgacctatgt actaaaatat tgacttcaaa aggtgaaaga
    11701 aacattaccg aattggataa aaagaatata catgagttat gtcttaacat gtctaaagat
    11761 gcattgcgtg tacttggttt tgctaagcgt gagatttcat ctataccgaa agaagatagt
    11821 gaaaacatag aatatgattt gacatttata ggtatagttg gtatgattga cccaccaaga
    11881 actgaggtaa ttgatgcagt aagtacttgt aaagaagcgg gtataagaac cataatgata
    11941 acaggtgacc ataaagttac tgccacaaca atagctcatg agttaggaat atggagtgaa
    12001 gaaaatactg tgatatctgg tgatgaactt gataatttga gtgatgatga actagatgaa
    12061 gctgttaaaa atactacagt atttgctcgt gtatccccat ttgataaact tagaattata
    12121 caatctttaa aaagaattgg agaagtacca gcaatgactg gggatggtgt aaacgattct
    12181 cctgccttaa agtctgctga tattggtata gctatgggta taagtggtac agatgttgca
    12241 aaagattctt ctgacatgat tttaatggat gatagcttta cgacaatttc ttatgcaata
    12301 aaagaaggta gacgtgtata tagaaacata caaaaagtta tacagttctt gcttgttggt
    12361 aatatagcag agatacttac attgtttgta gcaatattat taaattggga tactccactt
    12421 cttgctgttc atattctgtg ggtaaacctt gcaactgcta ctcttccagc ccttgcgctt
    12481 ggagttgatc caccaagcag aaatataatg aagcatcagc cagtgaaatc aaccacttta
    12541 tttgaaaaaa atcttataca aagagttgtt actcaaggta tatttgtggc aataatgact
    12601 attttagcat ataaaattgg tcttaatata gaaaatcatt ctgtaggtca aacaatggca
    12661 ttttgtgtat tagcattttc acagatgtta cgagcattta gtcagcgttc aaatacagat
    12721 tcaatgttta atagaaacaa tggtaaaaat ccatttcttt taatttcatt tttaacttct
    12781 gcattgctaa tagcagtgat actgtttgta cctgttttta gaaatgcttt taacttaaca
    12841 attttaaata gcttagaatg gcttataacg attgctttgg ctataatgtc tgtagttcaa
    12901 gtagaggttg ggaaaattat taaaagaaaa aaattaaaaa atagttgaca aaattaggaa
    12961 aaatatataa gatataaaac atagaaaaat taaataaatc ttatccagag aggtggaggg
    13021 actggcccta tgaaacccgg caaccagtat atttatatac aatggtgcta aatcctgcgg
    13081 cgaaagctga gagatgagta taattaagct tatacagagc ctgagttata tactcaggct
    13141 ttatttattt taactctcat ctgataaata gtttaatttt ttactaaaat ctaaggggga
    13201 tacaagaatg tataataaag aaacaatatg tgtgcaagga aattataaac caggtaatgg
    13261 agaaccaaga gtattacctt tatatcaaag tacaactttt aaatatagca gtatagacca
    13321 acttgctgaa ttatttgact taaaagttga tggacatata tattcaagaa taagcaatcc
    13381 tactattcaa gcttttgaag aaaaaataag tttactagag ggaggagtag cttctgtagc
    13441 tgtatcatca ggtcaatctg caaatatgtt agcagtttta aatatatgta aatcaggaga
    13501 tagtatactt tgttcttcga aagtatatgg aggaacattc aatttattag gacctagtct
    13561 taaaaaattt ggtatagatt taatatcatt tgacttagat tcaagtgaag atgagatagt
    13621 agaacttgca aaggaaaata ctaaggttgt gtttgcagaa acacttgcaa atccaactct
    13681 tgaagttata gattttgaaa aaatagcaaa tgtagctaaa agaattaatg ttccatttat
    13741 tgttgataat tcattagcat ctccagtgct ttgtaatcct ttaaagtatg gagcaaatat
    13801 agttactcat tctactacaa aatatttaga tgggcatgct tcaagcgttg gaggaattat
    13861 agtggatggt ggaaacttta actgggataa tggaaaattt ccagaattag ttgaaccaga
    13921 cccaacgtat catggaataa gctatactca aaaatttgga aatgctgcat atgcaactaa
    13981 agcaagagtt cagttgctta gagactatgg aaattgttta agcccattca atgcatatct
    14041 tactaattta aatgttgaaa cactacatct tagaatggag agacatagtg aaaatgcatt
    14101 taaaatagct aaatttttag aaaaacatga aaatgtagat tggattaatt acccaggact
    14161 tgaagataac aagtattatg agaatgccaa aaagtattta tcaaaaggat gtagcggagt
    14221 cttatcattt ggagtaagag gtggattaga aaatgctaaa aaatttgtgg aaaaactaca
    14281 gatagcatct ttggttacac atgtttcaga tgtaagaact tgtgttatac atccagcttc
    14341 aactactcat agacaattaa cagaagaaca attaattgca tctggagtat tgccttcgct
    14401 aataagattg tctgttggaa tagaaaatgt ggaagattta atagctgatt taaatcaagc
    14461 tttaaatttt taatattcta agagaaagag aagtgaaaag atatggcttt aatactacca
    14521 aagggattac ctgttattaa taaattatta gatgaaggaa tagatgtaat ttacaaagaa
    14581 gattttaaaa agaaattaac atatgaagaa aacatagata ctaagatagc catactgaat
    14641 ctaatgccta taaagataga tacggaatta gatttattaa gaaggataga taaaacagga
    14701 ttcaatgtgt ctgtggaatt tattaaaatt tcaacaagag aaagtaagag aagttgtaat
    14761 gaatatgtca aagaatttta taaaacattt gatgaagcca aaggagagta ctttgatggt
    14821 tttataataa caggagctcc agttgagcaa atggagtttg aagaagttga ttattggaat
    14881 gaattagaag aaattatgga ttattctaag agtaaaacta aatctacatt atatatatgt
    14941 tgggcagctc aagcaagtct ttacaaatac tacaatgtaa aaaaacttcc attaagtcaa
    15001 aaatgttttg gagtatttaa gcataaggta gataaaaata gtaaaatagt agatggattt
    15061 gaaaatgaat tttttgctcc acattcaaga catactactg taaatattga agctctgaaa
    15121 gagaataaag agttgagcat tgtgagtcat tctaaagaag ctggtcctta tataattaca
    15181 aattcaagag acgtgttcgt aatgggtcat agcgagtatg acaaatacac ccttgacaaa
    15241 gagtataaga gggatataaa cagaggagat aaaatatcga tacctcaaaa ttactatatc
    15301 aatgacgacc cttcagaaga gccaactgta aaatggaaaa aacattcgga actacttttt
    15361 agaaattgga taaaaaacta tttgatacaa taaattttaa tagtaaaata tcaactaaat
    15421 aaaatataaa aataataagg tataaagtta attttaacga ttctttatac cttattattt
    15481 taaaaaaatt gaccttataa tagtagtttt atatataaga taataaaatt ccaactgaag
    15541 ttacaatatt gtaattgaca atagatactt aatattataa tatttaatac attaaacatt
    15601 atagtattaa gtatttattt acaagataca cttaagccta aagttaatag ttagtgaaat
    15661 aaagtatttt tgtaaggagc gtttgtatgg atgagatgag ttttaagaaa gagctactag
    15721 agttgactag agatataaat atgaaattta caactttatt aactaaattt tatcagccac
    15781 ttggtattac agcagttcaa gctttgattt tgtctgagtt gtgtgaacat ggagagaaaa
    15841 aaataagcga tttagggaaa aacttaaaca tgacaaatag taatgtatca gtaatctgtc
    15901 aaaggcttga aaaaaatggt tttttaaatc gtataagaga tatagaagac caacgaattg
    15961 taaaagtaaa agttaccaat aaatcattgg atatacaaga gaatatttca agtagtattt
    16021 ttgataatta ttttgaaaat atgactagtg aaaaattgca agacatggaa gatataatag
    16081 aaggtttaga gaaattaaat aaacttttaa cctacattga ttgcaaataa cataaaataa
    16141 tttaaaggag aataaaatta tggatgaaca taaaccccaa aaaaggtctg cactctatta
    16201 ttatacagtt ataataatag tagtaatgtt tttaaatgct ttaatatttc caagtttaat
    16261 ggataagaaa atggttgaga ttgactatgg gaagtttctt acaatgttgg acacaggaaa
    16321 ggttaaatct gttgagatag aaaacaatag aatagcaata aatccatcta gtagtaagga
    16381 taagaatata tatataactg gtagaatgga tgacccagaa ttggtagata gactaaaaaa
    16441 tgcaaaagta gaatttacta aggttattcc taaggaaaat tcacctcttt taaacatttt
    16501 acttacatgg ataataccta taggtattct tatgctattt ggtaatttaa tgatgaagtc
    16561 tatgcaaaag cgaatgggtg gtaatgctat gcaatttgga aaaagcaatg ccaaaatgta
    16621 tgtatctgct caaagtggaa aaagatttaa tgatgtagct ggtcaagatg aggcaaaaga
    16681 agctttaagt gaaatagtag atttcttaca caatccagaa aagtataaaa aaataggagc
    16741 acaaatgcct aaaggtgcac ttttagtagg acctccaggt acaggaaaaa cactacttgc
    16801 aaaagccgta gcaggtgaag caaatgtacc atttttctca atatctggtt ctgagtttgt
    16861 tgagatgttt gtaggaatgg gagcttctag gattcgtgat ttatttaaac aagcaaaaga
    16921 aaaagctcca tgtatagtgt ttatagatga gattgatact attggtaaaa agcgtgataa
    16981 tggaagtgga ctaggtggaa atgatgaacg tgaacaaact ttaaatcagt tgctaagtga
    17041 gatggatggt tttgatggtg gaattggagt agtaatactt gctgctacaa atagacctga
    17101 cagtcttgac aaagcattac ttcgtccagg aagatttgat agacgtatac cagttgaact
    17161 tccagacctt ggaggacgtg aagctatatt aaaggtacat gctcaaaatg taaatgtaag
    17221 ttcagatata gattataatg caattgcaag gtctacatca ggagcatcag gtgcagaact
    17281 tgcaaatatt gtaaatgaag cagcactttt agcagttaag tctggtagag atatagtaga
    17341 gcaacaggat tttgatgaat ctgttgagac tgtaattgct gggtatcaac gtaaaggagc
    17401 tgtaatttca gacaaggaaa agaaaattat agcgtatcat gaaataggtc atgcacttgt
    17461 tgctgctatg caaaaacatt ctgcacctgt tcataagatt actataatac ctagaacttc
    17521 aggagcattg ggatatacta tgcaagttgc tgaagatgag agcgtcctta tgtctaaaga
    17581 agaagcaatt gacaaaataa ctacttttac aggtggtcgt gctgcggaag aggttatttt
    17641 taacacttgt acatcaggag catcaaatga tatagaacaa gccactaaaa ttgcaagagc
    17701 tatggtcact cgtcttggta tgagtgaaga atttgatatg gttgctcttg aaactgtaag
    17761 caatcaatat ttaggaggag atacttccct tgcttgttct tccgacactg ctgctaaaat
    17821 agatgaagaa gtatttaaaa tagtaaaaac ttgtcataaa aatgcaattg aaatcttaga
    17881 aaataatatt gataagttgc atgaacttgc taagtattta ttagaaaaag aaactataac
    17941 aggtgatgaa tttatggaaa tacttaactt aaactaaaat gattatacac aaagtaaaaa
    18001 tgcctattgt taggcatttt tattttgtaa ttaagttttt taaattcata tttaaatctt
    18061 tacataatct taatcactaa aaatacatct taactacaat tttatattgg aattgatatt
    18121 ataatagtaa tgaatgatgt aaggaggttt tttaatggat agaccgaatc ctgatattct
    18181 attagaaaaa ataaaaaatg aagaagaaaa actaagtaga ggtcaattaa aaatattctt
    18241 tggttatgca tcaggagtag gaaaaaccta ttctatgttg gaatctgcac aaaatttaaa
    18301 gaaagtaggt gttgatgtag tagttggata tattgaacca cacactagac cagaaacctt
    18361 ggctttactt gatggattgg aaattctccc tgtaaaggag atagaatata aatctataaa
    18421 attaaaagaa tttgacttag atgctgcttt agcaagaaaa ccagaagtta tattagtaga
    18481 tgaatttgcc cattctaatg ttgctgggtt aaggcataca aaaagatggc aagatataga
    18541 ggaattgctg ttagcaggca taaatgtcta cactactgta aatgtacaac atctagaaag
    18601 tctaaatgac attgttgaga taattacaaa cgtatcagtt aaagagacta taccagataa
    18661 gtttttggat acaaatacac agttagaact tatagatgtt gaacctgatg tacttcttga
    18721 aaggttcaat gaaggtaaga tatataagaa agaacaagct actagagcaa aaaataattt
    18781 ttttataaaa gataacctag ttgcacttag ggaaattgca cttagaaaaa cagcagaaag
    18841 agtcaataaa gaagttcaaa tgaccagact atcaaagggt gatgtaactg taatacctac
    18901 atcagatacg cttcttgcat gtataagtcc atctccatct tcagcaaaag ttattagaac
    18961 tgcatccaga atatcagaca gtacatttgc aaaatggata gctttatatg ttgagactcc
    19021 aaacacagca agacttccat ttgacgaaca aaaacaacta caaaataatc taaaactagc
    19081 taagaagcta ggtggagaaa taattgtttt acatggtgaa aatataatag agcaaatact
    19141 tagaattgca aaactgagaa atgtaacaaa aattgtaata ggtagaaatc attcaagtaa
    19201 taaaaggttt agtaaaaagt ttaaaaaaga tatagttgac aaattaattg atgaagttga
    19261 ttatatagat atacatataa ttccatataa atttgcctca gatgttaaat acaaacctaa
    19321 aaaggataaa gtgtcaataa aatctaaatt taaaattagt aaagttgatt ttataaaact
    19381 tatatttatt actttgatga taagtatttt agcatatgca gtacaaagta tgggctttat
    19441 aagagaaaat atattgttaa tatatatgtt gggtgtggtt ttagtttcta tgtggactaa
    19501 aggttatagt acaggtataa taagttctgt atttaatata gttctgttaa attatttttt
    19561 tacagcacca ttatatacat tatctatagc agattcaaac tatatagtaa cactagttgt
    19621 attttcaata gtaggtataa taactagtac tcttacatct aagatacaac atgaagcaga
    19681 aactgcttct aaaagagaag aaaatacaaa aatgatatat caaataatta agggattttt
    19741 aagattatca aataaagacg atataataaa caaaggtata gaacttttgt ctcttagctt
    19801 aagtagagat gtgatttgtt atttaaatgt agataagtat aacaaatcga agctttataa
    19861 aaaaaatact aataataagg ataaaaatga tttggatagt gaagatgaaa aagctgttgc
    19921 aagttgggtt ttatccaatt caacagtagc aggaaatgat acggatacac ttcctggttc
    19981 aaagggatac tatataccaa ttgtagggat gaatttaact ttaggagtag taggaatatc
    20041 atgtgttgat tcaaaattgg atacagaaga tataagctta attgaaacaa taattgctca
    20101 aatggcaata gcacttgata gagaaatctt gtcagaagct aaagaaaata ccaatctcga
    20161 gattgaaagg gaaaggctaa gaagtaatct tttaagagca gtttcgcatg accttagaac
    20221 tccactagca ggaatatctg gcgcagtaag tacaattata aaaaacaagg gtactatagg
    20281 tcaagatata atagatgaat tgcttagtgg tgtatatgaa gatactcaat ggttaataag
    20341 acttgttgaa aatttactta gtatgaccaa gatagatgaa ggaaaattgg aagttaaaaa
    20401 acattctgaa ctagttgagg aaattatatc agaagcatta caaaaaataa aaaaaagaat
    20461 tgaaaatgca cttatagata tcaatatacc agaacagata ttatttgttc ccatggatgc
    20521 aaaattaata gaacaagttt taattaattt aatagacaac tctttgaaat attcaaagga
    20581 agattgtaag atagagataa atgtatatga gaaagatgat tatgtttggt ttgaagtatc
    20641 tgataatggt cctggtatat caaaggaact taaaaagcat atctttgaca gattttttac
    20701 tggagaagaa ggagctaaag attccagaaa gggtgttgga cttggattat caatttgtaa
    20761 gtctataatt caagctcata aaggtgaaat tatggtagaa gacaataaag ataagggctc
    20821 aacttttaag tttagtttgc ctaaggaaaa tgaatagttt taaattttaa aattagtttt
    20881 ggaggaagaa atgagtaaaa aacttatatt gttagtagag gatgataaga caataagaaa
    20941 atttatatct actgcacttt taacacagga ttatgatgtc aaggaggcta taactggaaa
    21001 agaaggtata tctattgctg tttcatattc tccagatgtt gttctcttag atttaggctt
    21061 agaagatatg gatggaatag aggtaataaa agctatcaga caattttcaa atataccaat
    21121 aattgtagtt tcagctagag agcaagatag agataaggta gaagtatttg atgcaggggc
    21181 agatgattac ttaacaaaac cattctctat agtagagtta ttagcaagag taagagtcgc
    21241 atttagacat tcacaagtag aagttcaaca aaaagatgat gttaaatcta cgtttgaagt
    21301 agataaatta ttgattgatt ttgataaaag aaaagttatt gttgatgata ttgaagtcca
    21361 tttgacacct attgaatata atattctttc attacttgca aagcatcatg gaaaagtgct
    21421 tactcataac tttataataa aagagatatg gggtagtgtt atagggaatg agactaagtc
    21481 tttaagggtc tttatggcaa cattaagacg aaaaatagaa aaacaacctg caaacccaag
    21541 atatataatc acagaagttg gtgtaggata cagattaaat gatgaatagt tgtaatatat
    21601 attaattatt agactatgtt tttattaata tattaaaatt atatagttta gttaaaataa
    21661 gaatgaagtg tatgtgctgt tgtcagttta gcacatgcat tttatttttt aaattttttt
    21721 agtatcaata attttttagt attaataata tgaaatatgt tttaaaataa gtatatggta
    21781 taatctgtaa taaaagcttt ggttaaataa taaatgtact taacacttgt cttataataa
    21841 atttaatatt tatattaaat aataattatt aaaatagtgt aaaataatta cagtaaggat
    21901 tataaaaaat ttttagaatg taaattgaaa tttaggagta gatgtatgta tatactgaat
    21961 ttaaatacaa gagagactat tgaagatttt agagataaat tttatgtagc agaaaattct
    22021 tatcttatat taagtgctcc aaaaaattta aaattgctta aagaaacatt ggatatagat
    22081 gaaataactt ttaatgattg tcttaaattt gatgaaataa ccaaacttga tttatttgat
    22141 aattacgatt ttttaagcct aaatacattt gaattaagag atggtgaagc tgttatagaa
    22201 gaggtaaata tgtatttgtc tgataatttt atattggttg tagttaatga agaacacttt
    22261 ttatttgaat ttgtaaaaaa tattattttg aagaactctc aacttgaaaa aaatccagtt
    22321 attaacctat ttaagataaa ctacttgatt ctcagagaag ttataaaaaa tggttttgag
    22381 tctttggaaa aagttgaaga gttgattctt caaatagaag atgaaatgat ggacaacatt
    22441 aacaagaatc atgtatctag aataagtgat gtaagaggat taacaaggat tatagttaag
    22501 aatactagac ctcttttgta tattggggat agaatagtta aagaaaatat aagatattta
    22561 aaatattcaa atgtaaaaaa atataattta gaaaattttc aaggtataga ttttggaatt
    22621 gataaactat acagtttcgc attgtcaaca cgagagttag cagataaatt attagatatt
    22681 tattcttcta gagtaggtga aaaaacaaat aatttaatta caaaattaac cttattaaca
    22741 gccatatcag caccacttac aattataact ggtatatatg gaatgaactt tagatatatg
    22801 ccagaattaa actggattta tggatatcca gcaactttat tttttatgtt atgtataatt
    22861 tttgttggaa ttataatatt taaaataaaa aaattattgt aaattacaga tgatttttaa
    22921 ttaattttat aaaaatacat caattgagaa gccgatttaa gtaaataaaa aaatatttta
    22981 aattgaaaat atttatagaa aatattgaca attgtatttt ctttgttata attagtaaac
    23041 aagaagaata ataaattata aaaatggagg ataatactat gaaagggata ctaaaagaac
    23101 tagcagcaaa actttatagc tttttttact ttatgttctg gggcttttat tttagcgctg
    23161 gctatttctt ttacaaaaat atatgtaatt cctttctggt gaggccttat tttagtaatt
    23221 ttgagcataa gtaaatttta taaaaatgat tattttatat atttatgtaa gatttaatgc
    23281 ttgatagatt attttagaga actcattagt gagttctctt ttttatttta aatataaaat
    23341 tataatattg ggaggtagta aaaatgatag tagtattaaa aataggagca gataaaaatg
    23401 aagttaaaaa attaattgag gctattggga gagaaggagt agaagttaat cccatagatg
    23461 ggacagaatt aactgtttta ggtttagttg gagatactag taaaatagat gccaaaagaa
    23521 tagaagcaaa taagatagtt gaaaaagtta tgcatgtagt agagcctttt aaaaaggcca
    23581 atagaaaatt tcatccagaa ccttctataa taaatgttaa tggaatggaa attggttcga
    23641 aaaaaattgc tatgatagct ggaccttgtt ctgttgaaac agaagagcaa atagtatcta
    23701 tagctgagga tgtgaaaaaa tcaggtgcag gatttttgag aggtggagca ttcaaaccaa
    23761 gaacatcacc atacgctttc caaggattga gatatgatgg attggactta ttaaagaaag
    23821 caaaagaaaa aacagggctt cctatagtta cagaaataat gtcaacacaa gatatagata
    23881 tatttgaaga aaatgtagat gtaattcaag ttggagctag aaatatgcaa aactttgatt
    23941 tattaaaaga attgggtaaa acaaataaaa caatactttt aaaaagagga ttatctgcta
    24001 caattgaaga gtggttaatg tcagcagagt atataatggc tggaggaaat gaaaatgtag
    24061 ttctttgtga aagaggtata agaacttttg aaacatacac tagaaatact ttggatttaa
    24121 gtgcaatttt agctgtgaag aaacttagtc atttgccagt tatagttgat ccaagtcatg
    24181 cagcaggcaa atcatggatg gttgactctt tatctaaggc agcaattgca gttggagcag
    24241 atggtctgat aatagaagtt cataatgacc cagcacatgc actttgtgat ggaaaacaat
    24301 caattaaacc aaatgaatat gatgaattaa taagtgaatt aaagactatt gcatcagcag
    24361 taggaagaga aatataatct ataaaaggat ggttaaacgt ggaagaaaaa ctattagtaa
    24421 atttaaaaga aaatagctac aatatattta ttaaaaaaaa tatactaaac aatgtaggag
    24481 aggaaataaa aagaatatat tttggaaata agatttttat tgtaactgat gaaaatgtag
    24541 caaaattata cctggataaa ttaaaaaata atttaagtga atctggattt gaaataaaat
    24601 ctttaatatt aaaatctggt gaagaaacaa agtcatttaa tactcttcct aaaatatacg
    24661 atagtttact tgactttaag ttaactagaa aagatttgat tattacttta ggaggagggg
    24721 taataggtga tttaggtgga tttgcagcag caactttttt aagaggtata aattttattc
    24781 aaattccaac atctttatta gcacaagttg atagttctgt aggtggaaaa gttggagttg
    24841 accttgagag aggtaaaaat ttagtaggaa gcttttatca accaaaagct gtatttattg
    24901 acccaaatgt attattatca cttccagaaa aattctatag agatggaatg gcagaagtta
    24961 taaaatatgg atgtataaaa gataaaactt tttttaataa acttttaagt ttaaaaaata
    25021 gagaagaagt aatgcaacat atagaataca ttatacataa atgttgcttt attaaaaaaa
    25081 ctgtagttga agctgatgaa aaagattttg gggatagaat gcttttaaac tttggtcata
    25141 cattaggtca tgctattgag aaacactaca attttacagg ttatactcat ggagaagctg
    25201 ttgccatagg aatgtataag ataactttag aaagtgaaaa gataggaatt acaaaaaaag
    25261 gtacatcaga acttataaaa tcaattttaa tgaattataa tttgccttat gagattgaac
    25321 taagagataa taaatctata gtagaagcta tatctcttga taaaaaaaat ctaggtgata
    25381 cattaaaaat aatactttta aaagatattg gagagagtat tatatataat actacttcta
    25441 aattttttca ggaggtaaga taatgggaag tctaaaaata tatccaagta aattatctgg
    25501 agatgtaaaa ataccaccat caaaaagtat tgcgcatagg gcagttattt gttcatctct
    25561 aagcaatgga aaaagtagaa tttctaatat agatttttct gatgatataa tagctactat
    25621 aagagcaatg acatcattag gagctattat agaaaagaaa gaagatattt tagaaatttc
    25681 aggaattttt tcgaaggaag gtattttaaa tagagagaat cagttgaatc aacctaaatt
    25741 gacaatagat tgtaatgaat caggctctac attgagattt ttagtaccta tatctttagc
    25801 atttgatggt gtaaaaaggt ttataggtag aggtaatctt gggaaaaggc cacttgatac
    25861 ttattatgag atatttaaca gacagaatat aaaatatagt tacaaagaaa atcagttaga
    25921 tttgattata tcaggtaagc ttaaaccaga tgagtttaga gtaaaaggaa atataagttc
    25981 tcagtttatc acaggtctat tatttatatt gcctacatta gaaagtgatt caaagataat
    26041 aattactact gagttagaat ctaaaggata tttagattta actctttcaa ctatgaaaga
    26101 ttttgggata gaaattataa acaataatta taaagaattt attataaaag gaagtcaaac
    26161 gtataaagcg agagattata aagtagaagg agattattct caaggagcat tttatttatc
    26221 agcagatgct ataggagaag atattaatat attggacctt aaagaagatt ctcttcaagg
    26281 agatagtgaa gtagttgaaa ttttatctag gatgggaatg gaaatattaa gagagggtaa
    26341 caaaataaaa ggaataacaa atggtttaaa tagtactttg atagatgcat ctcaatgccc
    26401 agatataata cctgtattat ctgtagtagc agctttaagt agagggaaaa ctacaataat
    26461 caatgctggt agacttagaa ttaaagaatg tgatagactt catgcaataa atattgagtt
    26521 aagtaaactt ggagcgaata tagaggagaa agaggatagt ttgataatcg aaggagtaag
    26581 taagttaaat gggggagtag aggtgtggag tcacaaagac catagaattg ctatgacact
    26641 tgcaattgct tcttgtagat gtgataaacc aataatacta aaagattttg agtgtgtatc
    26701 aaaatcttat ccacattttt ttaaagattt tgagatgtta ggaggacgaa ttgatgagtg
    26761 gaatatgggg aaataattta aaaatatcca tttttggaga atctcatgga aatgctatag
    26821 gtataaatat agatggtctt ccttcaggag tggaacttga ccttgagaag attgatagag
    26881 aaatgaagag aagagcacct ggaaaaaatt ctatatctac ttcaagaaat gaaagtgata
    26941 taccagaaat tctaagtgga tattttaatg gaagaactac aggaacgcca ttatgtgcaa
    27001 tcataagaaa tagtgatact cgttcaaaag attatggaga acttaaaaat ctaatgagac
    27061 caggacatgc agatttcaca ggaaatgtga gatactctgg atttaatgac tacagaggtg
    27121 gaggtcattt ttcaggtagg ataacagctc cattagtatt ttgtggggct atatgtaaac
    27181 aaattttgtc acaaaaagga atagaggtag gagcacacat aaaaaaaatt aaaaatatag
    27241 aagatatgag ttttaattat gtaaatattt caaaacaaca gttatcaaat ttgcaaactt
    27301 tagaattacc tttacttgat ttatcaaagg aagaaaaaat gaaaaatact attatagatg
    27361 caaaaaatca aagagattca gttggtggta taattgagtg tgcagtagta ggtgttaatg
    27421 tagggtttgg aaatccattt tttgattctg ttgaatctac tttatcacat ttattgtttt
    27481 ctgttcctgc tgtaaaaggc gtagagtttg gtttaggttt tgaacttgca gatatgtatg
    27541 gttctcaaag taatgatgaa atgtattatg aaggaaatca agttaaaagc aaaacaaata
    27601 ataatggagg aattattgga ggtattacga ctggaatgcc aataattttc aaggtagcaa
    27661 tcaagccaac tccatcaatt agtagacaac aaaacacagt taatataaaa gagaaaaagg
    27721 acgatatttt atctattaaa ggcagacatg acccttgtat agttcaaagg gttatacctg
    27781 taatagaagc agtaacggcc attggaattt ttgatttgat gaaaggacga taataatgga
    27841 ggatttaacg agatatagaa atgagattga caatatagat aaagagctta ttcaattatt
    27901 tgaaaagaga atgaatacag ttcttgaaat tgccagacat aaaatgaaaa ataacactac
    27961 tatacttcaa aaagatagag aagaaaaagt actaagtaga gccgtagata atttagacaa
    28021 taaagcctat tcacaagaaa caatacaatt ttttaattct ataatggaaa ttagtagagg
    28081 attacaaaaa aggttgatgg ataatgatag tgagcagaaa attgaattta ggctagactc
    28141 atcaaagaag aaatttgact tgtcaagtgt aaataaatat aagtctttaa aagaagaatt
    28201 aaataaaaaa aatatcctag taggttttcc tggaaaatca ggttcattta cagaagaagc
    28261 actaaataaa ttcttcaaca aaaaaacagc aaaaaaacaa tttaaagaat ttgaagatgt
    28321 tttcatagca cttaaaaata aaaaaataga ctatggaata attcccatag aaaattcatc
    28381 cactggtgct atctctgaaa cttatgacct tttaagaaaa tacggttttt atatagttgg
    28441 agaagaatgc ataaaaatag accaaaattt aattgggata aaagatacaa aacttaaaga
    28501 tataaaagaa atatattctc acccacaagg tataggacaa tgtagtgaat ttttaaaaca
    28561 aaatagtgca tggaagttaa taccatttaa taacacagca acaagtgctg aacttgtaaa
    28621 aaaacttcaa gataaaacaa aagcagcaat tgcaagtaaa aaagctgcaa gtatttatgg
    28681 attagaaata ataagtcctt gtataaatga tattacaaac aactatacaa gatttgtagt
    28741 aatcagtaat caaatacaca ttgaagaaga gtcaaacaaa atgagtgtag tgttttctgt
    28801 tgaacataaa gcaggaaagc tttataaagt acttggatac tttgctgaaa ataatataaa
    28861 catgacaaaa atagaatcaa gacctatgaa aaatacctca tggagatatt tcttttatat
    28921 agatttcgaa tgttctatat acaattctaa agtatacaat ttgttagaat tgatagaact
    28981 taatacagcg tattttaaat ttatgggagt atataaaaat aaaactaaat agataagata
    29041 aatttttatt taattattag gaggtgtaaa tatgaatttt tttggtttag taggtgaaaa
    29101 actctctcat agtgtttccc ctcaaatcca caagagagta ttcgaaatat tgaatattga
    29161 aagtgcctat aaaaactttg aaatttcaaa agaagatgta tctaagctag ctagtgctat
    29221 aaaattatta ggaatacaag gagtaaatgt tactgtacca tataaagaac gtattatgaa
    29281 atatcttgat tttatatcac cagaggcaaa gcgtatagga gcagttaata caattttact
    29341 cagagaagat atgttatatg gttataatac agattacttt ggtcttgata gtatgtttaa
    29401 aatggctaat attgatgttc aaggaaaagt ggcagttata ttaggaactg gtggtgcttc
    29461 taaagctgct attacatatc ttctcgattc tggaatagag aaggtttatg tttcaactag
    29521 aaaaaaagat gataaaaaat tattaaatag taaagctata ttggtagatt atgaagaact
    29581 taaatgtata acaggagata taatattaaa tgctacacca gtaggtatgt accctaatgt
    29641 aggaatttca ccagtgtcaa aatctattat acaaaatttt gatacattag tagatttaat
    29701 ctacaatcct ggagaaacag agtttttaag aattggtaat agtattggta aaaaaacttg
    29761 tgacggttta tatatgttgg tagggcaagc gataaaatct caggaaattt ggcaaaatgc
    29821 taaaatagat aatagtattt tagatgttat atataatgaa ttaaaattag aatttttgta
    29881 agggagattg tcatgacaaa taaaacaaaa gaaaaattaa tattaatagg tatgccaggt
    29941 agtggaaaga ctacaattgg aaaacttttg gctagagaat ataattgtag tttttgtgat
    30001 atggatgatt atatagttaa aatagcccaa aaaagtatag cagagttgtt ttcagaagga
    30061 gaagatattt ttagaaacta tgaaactcaa gcatgtaggg aactttctat aagtaataaa
    30121 gcagtgatat ctacaggtgg aggtgtaata aaaaaggatg tcaatatgga aatattaaaa
    30181 gaaacaggta taataatttt tattgataga cctatacaaa agattttaga agatataaat
    30241 attaattcaa gaccgttatt aaaaaacgga aaagatagat tgtataatct ttataatgag
    30301 agaataaatc tatataaaaa attttcagat atagagattt taaatgacaa atcattaaat
    30361 actgctgtat ataatattat aaatgcagtt agtgaaaaat ttaaatttga atttaaagaa
    30421 aaataatcta ggaggaaata aaaataatga atattgttat tgtaggatta ggagttatag
    30481 gaggttcttt tgctaaagca ttaaaaaaag ctggatatga aaatgtattt ggagtagatg
    30541 tagatttaga aactttaaaa aaagcagaaa aagcaaaaat cataaaaaaa ggatgtacta
    30601 caggtaaaga gttatttaaa aaagctgatt taattatact atctatatat cctagattag
    30661 ttgtagattt tctaaataat aataaaaact tttttaaaaa aggaactata attactgata
    30721 ctacaggaat aaaagaaaca cttatcaatg atgtgttgca aattattcca gatgatatag
    30781 attttatatt tggccatcca atggcaggca gagaaaaaag gggaattgat tttgcaagtg
    30841 aacaagtttt taatggcgca aattacataa ttactccaac tggcagaaac aacataagga
    30901 atttagagtt agttgaaaat ttaattttaa aacttggatt taaaagagta aaaaagttaa
    30961 cttcacaaaa acatgatgag attatagctt ttacttctca gttacctcat gttatggcag
    31021 ttgctcttat aaatagtgat gaagaagata gagatacagg taaatttatt ggagatagtt
    31081 atagagattt aactagaatt gcaaatatga atgaagactt atggagtgaa ctttttctag
    31141 ggaatagaga taatttacta aaagttatag aaaactttga atcagaagta aacttaataa
    31201 aagaagctat atttaacaat gataaaagta aattgataga gtattttaaa aaatcatcaa
    31261 taaggagaga aattttagaa aaataaatat tgatatttaa gctgtatata gatgggtata
    31321 aatataagcg atagtgtatt taattgtatt aataaatatg gattcaatat aattaaatat
    31381 gctattgata tatttgtacc cttaaatatt gttatctttt aaatgataat gacatttacc
    31441 taaatactct ttattaacaa tttataaaac ttaattgtaa aaaatactta ttaatagtaa
    31501 aataaagtga atcaattata ttataattgc taaagagggt gaggtgtagc tatttgaaaa
    31561 aaatatatta atagtaagga atgtatcaat agcatttata gtactattct tttttagtgt
    31621 atttgcattc ttttatgtag ccaatattaa tagggtgtta gaatatgaaa caaataactt
    31681 aatgacaatt acaattactg gatggattat actttctttt ttatttttag gtattataat
    31741 ttacatatta tattcaaaag caaagagtca aaaaactata gaaaaagtag catatacgga
    31801 ttttgtaaca ggttattcca actggagaaa gtttgaattg gatgttacaa atttattaaa
    31861 gaaaacatcg caaaataata aatatgcaat ggtcatattt gatattgata aatttaaagc
    31921 aattaatgat atatatggcc ataaaaaggg aaatttaata ttaaaagata ttgcagatac
    31981 tttaaatgaa ttgattaata tcaatgaaac ttttgctcgt gtaagtgctg ataattttaa
    32041 catattatta acatataata aaaaagagga tataataaat attatcaaaa agattatggt
    32101 aaataatgaa cttgtaaact tatcttttgg aatttatgaa attaaagata aggctctatc
    32161 tgtaagtgta tatagtgaca gagcctcact tgcaaaatca tcaataaaaa ataatagtga
    32221 tgtaaacttt gcctttttta atgatgaatt aagagagaaa ttattacttg aagataagat
    32281 agaaaaagaa atggaatatg ctcttgaaag tgggcagttt gtaatgtatt tacaaccaaa
    32341 atataatatt aaattaaata aattttgtgg aagtgaagct ctagtcagat ggcaatatac
    32401 agaaaaagaa gtcatatatc caggtgattt tattcctgta tttgaaaaaa ataggtttat
    32461 tagaaagatt gatatgtaca tattagaaca agcttgtaaa gaaatccggt ctttatttga
    32521 taaaggaatt tcacctttac ctatatctgt aaacttttca agagttgatt ttttaaaaaa
    32581 agattttatt tcaaacatag taaatgtatg tgatagatat aaaataccat atggtttaat
    32641 agaaattgaa attactgaat ctagcatgtt tggagatact gatattctat ttaatgtgag
    32701 taggaatcta caagatattg gctttatagt tgcaatggat gattttggtt caggatattc
    32761 ttctgtaaat atgcttaaaa atataccatt aaatgtaata aaattagata gaggattttt
    32821 tgttgatgat aaagatgttg acaagagtca aattgttata aaaagcatag tttctctcat
    32881 taagcaatta ggaataaggg ttgttgctga aggaatcgaa acaaaaagtc aaatagaaat
    32941 gttaaaaaaa gcaaattgtg atattgttca aggatattat ttttcaaaac cattaccaat
    33001 taaagaattt gaaaaattag tctataagat atagtcagcg agtcttaaat gggaggtggt
    33061 gattaagtga taagagcaaa atcgttaaaa aatgtactga gtattgtttt aatattttta
    33121 tttacaataa tttctttttc tgattttgca tttaaaacta atgtccaaga agaagaaaat
    33181 agtaaaatta atttaaggga aatatcctta caaagttcca atgctataaa aataaaacta
    33241 gacagttctt tgtcctttat taaaagcatg gcaaatatgg tttcgtattt taatactata
    33301 gataactcaa aaataattcc attattagct aatatatcaa aagaatctga ttttcaaaga
    33361 atttctattg tatctcctga tggaataagc cataccagcg atggcaaaat tattgatgtt
    33421 tcaaattatc aatattttaa gaaagctatt agtggagaaa gtaatatatc tgaagttgta
    33481 aaatctccaa ttgatggaaa ggatactttt gttatagcta ctcctatatt taataagaat
    33541 aacaaaataa ttggtatttt atatggttct tactacaatg ataaattagc tgaatttata
    33601 gatataacaa gttttaatag tgaagggtac atagatatat ttgaatctag tggacaattt
    33661 gttctaaaat cttcacatac aaacaagttg attaagtcaa gtagtaatat atatgatata
    33721 tttaaaaaag cttcttttga tgatggttat agctataaaa aaatatataa agatacaaaa
    33781 aataacaaga gtggctttac gtcatatgaa tataaaggag aaaatcgcta tgctacttat
    33841 acaccaattg gtgtaaatga ttggtatgta atttctgtga taccacaata tactgtaagg
    33901 agaaacattg ataaaataaa tcaattagca ttttctctta ttttcaaggt attcttgtta
    33961 tttattatac ttataatata tattatttat aagaataata aatctcagag agatatacta
    34021 aaagctaaca aagaaatctc atctattaca aatagcattc ctggaggagt acaaaaatgt
    34081 accttgggtg aaacatgcaa aatcaatttt ttaagtgatg gatttataga gttgttcggt
    34141 tatacaagag aagaaataaa aacattgttt aataacgatt tttatagttt aatacataaa
    34201 gatgatgttg aaagaataaa aaaagaaatt tctaaacaac tttacaaaaa taaaactatt
    34261 gaattagaat atagaattat aacaaaaagc ggtaatacag tatgggtttt agataaggga
    34321 gagcttataa cagaacctga tggaaaagaa tatttttgtt gtgtaactgt agatattact
    34381 agaacaaaac aattagaaca agagatggaa caaaaaaatc tagaacttga aatgatatca
    34441 gaaaatattt taggtggtat acttataaca gaacttaatg aagattttac tataaaatac
    34501 actaactctg gttatctttc aatgattgga tatacacgtg aacaattaga aaatgaactt
    34561 aaatataaag catgtgacct tgttttttat gaggatagaa agaaggctct ggaaagtata
    34621 caacatcaat taaatacaaa aggaatagct gtatatcaac atagaataag aagaagagat
    34681 ggtaatatta tctgggtttc tataaaagga aggcttatta ttgatgatga tggtattgaa
    34741 aaaggtattt ggattctaaa tgatataaca gatttaaaaa atgcagaaca aaaacttaaa
    34801 ataaatgaag aaagatttag aattgcatta aaacaaacat caaacactat atttgagtat
    34861 gatataaaaa ccaagtcact tttaaatact agcaaagagc ttgataagta taatatttat
    34921 aaaatcactg aaaatgttcc gtattcttta gtagaatcag gagttattca taaagatttt
    34981 agtaatgatt ttataaatat gtatgaaaaa gtaataaatg gagcaaaaaa agcaagttgt
    35041 gtagttaaga tgaaacttcc agatgaaaat tatatatgga ataaagttac tctaactact
    35101 atttttgatg aagatggtaa tcctgtaaga gcaattggta tacaggaaga tataagcaaa
    35161 caaaaagaag cagagataag atacaatcaa gaagggaagt atcattcagc tatattgtcg
    35221 gaagcaatga taacttatga aataaatgta tcaaaggata cttttatcaa aggcaatgaa
    35281 aattggcaaa aaccatttgg aattaaacca gacaataact attctcaaat ggcaaaaacg
    35341 atagcaaata gcattgtaca taaggagaat aaagaagtat ttttaaatac atttttatgt
    35401 gaaaatttat tagacgcata taaaaataat ataactgaaa taaaattaga atatcaaaga
    35461 atgaatcaag aaaataaaat gatttgggtc atttgcacaa tgcacttaat aaaagattct
    35521 attacgaatg atataaaagc acttgcttat gttaaagata tcgacaaaca aaaaaatgaa
    35581 gaaattagat taaaattaaa agctgaaaga gatactctta caggattata taataaaggt
    35641 actacagaaa aattgattaa tgatttctta aactctgaga aagcaagctt aggaatgcat
    35701 gcatttttaa ttgtcgatat agataatttt aaatctgtga atgataattt aggtcatgta
    35761 tttggagata aagtattatt tgaagtttct aaacacctaa aacctatatt tagaaaagat
    35821 gatatagtag gtcgaattgg tggagacgaa tttatagtat tcttaaaaaa tattcaatct
    35881 tttgagaatg ccaaaaagaa agcagaaaaa atatgcgata tatttagaaa ttcttatacg
    35941 aaaaataaaa agacatataa aatatctgga acagttggaa tttcatttgt accagaacat
    36001 ggaactgtat ttgaagaact ttataaaaaa gcagacatag cactttatta tgcaaagagc
    36061 aaaggaaaag ataagtatgc actttataat gattgcatct accaaaatga acttgaaaat
    36121 aatataagtg acaataatat aaaagtagca aataaatgtg aaaaatccaa tccagtgctt
    36181 aaagaagttc ttgattctat tgataattat atatatatag tgaatccaaa tacttatgaa
    36241 cttctttttg tcaataataa ggtgtctcgc tcaggtttag agataaaatt aggacaaacc
    36301 tgttataaat cactattaaa atctgataga ccatgtagta attgtcctct taacggatta
    36361 gaagaaaata aacattcaaa attcaaaata gagacaaata catttggtac aaatatcagt
    36421 atagccagtt ggattaattg catagacgga gaatataatt gtcttataga gtgtatagat
    36481 tcttctttat acaaaaataa ataaaaagga ctatgaagat atgttaaatg gtataacttt
    36541 gatacttggt ataatattta caatttacta tttttatctc aaaatagttt ttggaggaat
    36601 ttcatttagt gagattttct tagttgtagg aattatacta attatctatc aaatatttaa
    36661 gaaaaaaatc aaagaaaaga aggtttttta tagagtgtta aaaataataa tcagtgtttt
    36721 tttaatagta tttgtagtta ctgagagtct aattattttt tatcctaaaa atagtttaga
    36781 gtcaaaaagt gattatctct tgattttagg agcttctgta aaaaagacta taccaagtac
    36841 aaccctaaag ggtagattaa acacagcatt gaaatatcta aaagttaatg ataattgtta
    36901 tgtagtagta tctggtggta aaggaagtgg agaaaacata actgaggcaa aagctatgaa
    36961 agattatctt ataaaaaacg gtatagataa gaataggata atagaagaag ataaatccac
    37021 taatacttat gagaatttta agtattcaaa atttaagata gaagaacgta gtgaaagaaa
    37081 attaagtgat ttaaaagtaa aaatagtaac aacagatttt catgttctta ggagcaaaat
    37141 attagcatat agaaatggat ataaaaatac gtctttttat gctagtaaat caaaactttc
    37201 atttgtacct acttactata caagagaatt ttttgcatta tggaaaacaa tcttttttga
    37261 tagataataa atagaaggac tagatataaa ttataaattt atatctagtc ttttttatgt
    37321 agaaagtaag agttaaaaat tattttttca aagcttcctg ccattaaatt agaaaattta
    37381 gtctcagtat tttagaaaca ttaataatag taatataaat caatata
//
LOCUS       DAMKOJ010000037        37396 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000037 DAMKOJ010000000
VERSION     DAMKOJ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.039"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            175..951
                     /locus_tag="PC592_001952"
                     /pseudo
     CDS             175..951
                     /locus_tag="PC592_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
     gene            1106..1867
                     /locus_tag="PC592_001953"
     CDS             1106..1867
                     /locus_tag="PC592_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055927.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTVEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            1870..2688
                     /locus_tag="PC592_001954"
     CDS             1870..2688
                     /locus_tag="PC592_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HDF4055928.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            2867..3469
                     /locus_tag="PC592_001955"
     CDS             2867..3469
                     /locus_tag="PC592_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HDF4055929.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRVEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPGGIKNMIQDYLGEIIESEVKKSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIVQGLVTMFI"
     misc_binding    3959..4198
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4262..6181
                     /gene="thrS"
                     /locus_tag="PC592_001956"
     CDS             4262..6181
                     /gene="thrS"
                     /locus_tag="PC592_001956"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDF4055930.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSNEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            6906..7997
                     /locus_tag="PC592_001957"
     CDS             6906..7997
                     /locus_tag="PC592_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF4055931.1"
                     /translation="MIEKVGEKSKIIKTSKEYKRTIIEEKDREWTQKLNDILSRNNFS
                     NDELDKIKELIPKEILTSENVGEVVTEDGYARPEYDEVFKSLFTLNNEYGLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRLETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPEIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLIINPSSLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNAFDLSEDEIKEVYENN"
     gene            complement(8345..8542)
                     /locus_tag="PC592_001958"
     CDS             complement(8345..8542)
                     /locus_tag="PC592_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4055932.1"
                     /translation="MTIASDVIRCDTKTSILKHLLKKDSYSYEINKSILEKTKGLYEL
                     KEAILYTAFRRLEQSGAITSY"
     gene            8902..10242
                     /locus_tag="PC592_001959"
     CDS             8902..10242
                     /locus_tag="PC592_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF4055933.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKKISNKKINFCI
                     VGIIVFANIIYFFDAPLNIRVIISMIVTIAFYKISYDVRFIKSVLISLIYWMLLIAID
                     ALSISLTVWLNSINDMSNMGTGDIYRIESIILGKILLISALFLYRALKIKFNIEINKR
                     TLFYIVIPIVANIASFFVIFKYIFNLKFGNLIHNFQFVVISVVLLVSSITLILIAKKL
                     QQYNTLVVENNMIKNTLKCENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDRNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDIMQNFYLIKVENTKTNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKVVNNII"
     gene            complement(10584..11153)
                     /locus_tag="PC592_001960"
     CDS             complement(10584..11153)
                     /locus_tag="PC592_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF4055934.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
     gene            complement(11314..12564)
                     /locus_tag="PC592_001961"
     CDS             complement(11314..12564)
                     /locus_tag="PC592_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4055935.1"
                     /translation="MVKSLNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIIFSPIGGAIADIFNRRNLMVIFDFSSSITVLVLALFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQTSNIIKTIFIDINDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKYLKITNLYISFTICALMFIPMAFSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYAITIIQLKTPNELLGKVMSILFAGTTIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLIIAFISKITLRNEKL"
     gene            complement(12573..12806)
                     /locus_tag="PC592_001962"
     CDS             complement(12573..12806)
                     /locus_tag="PC592_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055936.1"
                     /translation="MIELIQRLNDVIYKINDKLNIHTKLVDPSSELMPLYSMLSIIVS
                     IFLIILGIKVRKKVLIVIAIIAIIVNVLIILDR"
     gene            complement(12857..13435)
                     /locus_tag="PC592_001963"
     CDS             complement(12857..13435)
                     /locus_tag="PC592_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4055937.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGTFYTFFDSKEKLFFEVLNGIQNRLISSVDEILGNMPQKEGFAKALKMLYRLYDKN
                     PFLYSPNNTDYITLLNKIPKEMLSQLEYNNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            13736..15196
                     /locus_tag="PC592_001964"
     CDS             13736..15196
                     /locus_tag="PC592_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF4055938.1"
                     /translation="MFNELRTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEAIKNTKESIKVWADMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     MKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVEKIKPLVENLTIGNPKDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLIVGNIRKNNLFYPTLLDNVNTDMKIAWEEPFGPVL
                     PIIRVKDISQAIEIANQSEYGLQSSVFTSDIDRAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVRGL"
     gene            15565..16170
                     /locus_tag="PC592_001965"
     CDS             15565..16170
                     /locus_tag="PC592_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4055939.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDDELSPQQCLRKIMLNHLRFP
                     KQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRLSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            16173..18740
                     /locus_tag="PC592_001966"
     CDS             16173..18740
                     /locus_tag="PC592_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF4055940.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGVLFHNGEMPQEVSDAIKTAY
                     DGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDEVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYTLTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     FLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIALQSEKE
                     LWGLSEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAYSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEALIEQLDKNKSLSDMNGLIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     ALQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(19000..21084)
                     /locus_tag="PC592_001967"
     CDS             complement(19000..21084)
                     /locus_tag="PC592_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4055941.1"
                     /translation="MSKYIDFANIEYSLLMNALDVSVSKHLLDEHFTVVWANDRYYEM
                     FGYTKEEYETLFHNQCDLFYKDNPEDWNELVEYVEKTFSTGAKKYDYVCRMKHRNGKK
                     LWIKLFGFLTGEVVDGYPISYSVMIDITEQMMIKIEQTVTYNNFPGLIAKFKVTDFGF
                     QLLDANKKYFDMFKDNVNFLLDDINLESYLSAVYKYQSDFKAGKYVCFSVSPQNINGD
                     IVHMQVVAECIDWEDGKPIYLLIYSDVTTLVKQNEIIEKNNKELEKLAFIDSVTGGMN
                     HTKFNIIAKEVISQSPSGTYTLIWLNMQKFKLINDLAGNIAGDKLLKYIYNCISKHLH
                     EGELVTRIFADKFILLLKDKPEDITSRLNSMVTHINRFNDNADYKYILYFTAGAYVIY
                     DTSLDITNIQDSANVASKSIKNVENHGLCICNFYSKKDKEKLILEQSIENRMYEALEK
                     REFQVYLQPKLELSTQTICGAEALVRWIHPVEGIIPPNEFIPLFETNGFIIQLDLYVF
                     EEVCKTLKKWIDDGLNPINISVNMSRYHFSSNNFIKTYDKIAKKYDIPSHLIEIEITE
                     TIVFEDVKVFSEIINEIHKNGFKCSIDDFGSGYSSINMLKDIYVDTLKLDRAFFQSEH
                     LDSQRERDIIVSIIELAKKLKMTTVAEGIETSFQKDFLQEINCDMLQGYVFSRPLPIK
                     DFEKLMFQNSSN"
     gene            complement(21132..22013)
                     /locus_tag="PC592_001968"
     CDS             complement(21132..22013)
                     /locus_tag="PC592_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4055942.1"
                     /translation="MPAYLFDSNYITNIYRVYSISSSFIVTGLYFCYKNHKNNQINFD
                     TVLEDKKNLNFLLSLMFVMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     KYSFRITQIKSYDIKNQLEYLESIKTEHEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     MSNHYKFTLCFTDLNRLKLVNDNFGHQFGDKYISTTAKIIKKLINVENSLLFRYGGDE
                     FLFLLQDTSCIEAEKIMIDINYELSKLSNTDEYPYALSISYGLVEWDGISDIETLIAE
                     ADSLMYENKLKNKSTLN"
     gene            complement(22363..23544)
                     /locus_tag="PC592_001969"
     CDS             complement(22363..23544)
                     /locus_tag="PC592_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4055943.1"
                     /translation="MKYHIFLIITIILIVELCNIYIYKIASFGNKSIAIHKNYKYIFL
                     IKPLTFLTIIFTKLPLPLFYILFYIVSHKLLLISIKNSDNKHFIPNIAVINFCILHLI
                     TISIMSIVENTSPDIIFVNMSSRIISILIASILDFILWYSMDKIKEHIYVITQNQIEF
                     SLFLKFIYFTLGYILFDSIQIAFSPPSALTSYFILGSNILLSLQMIIFINHIYSIEKN
                     IYLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNSLLFSL
                     IYIDLDKLKTINDKYGHLAGDNYIINFSSIIISNLKADDIFARIGGDEFIVIMPKSNE
                     NTTKEFIEKIRKSMYNKISFSYGIVEVPSENKMTVEEIINIADIRMYTNKQNNHKRNS
                     N"
     gene            24671..24946
                     /locus_tag="PC592_001970"
     CDS             24671..24946
                     /locus_tag="PC592_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055944.1"
                     /translation="MSLIVGGWSKFRAVEEEDLKVFNEAVGMLKGVDYEPLIVATQIV
                     AGTNFKFICNATSVTNPPHDYLAEIIIFNPLPCDKQKATITSINIVK"
     gene            24966..25253
                     /locus_tag="PC592_001971"
     CDS             24966..25253
                     /locus_tag="PC592_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055945.1"
                     /translation="MRLNITKQNTIEVEGSKKEDVYFIIVDNVFFERKGNVFYSITNN
                     NLNNYDIKILPTDNIFLELKITSTKDLEPVFIVAEDRQYNHCSVMFKPVMV"
     gene            25673..28189
                     /locus_tag="PC592_001972"
     CDS             25673..28189
                     /locus_tag="PC592_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4055946.1"
                     /translation="MPEDNKTFLYELKELLSNGEKQIAKAIGQDLILILGGTGCGKST
                     AINYLAGCEMHKVEDEDTGVSYITCEDPVADIGSGAVSKTLYPEVIDMKKGFEGMTAK
                     FCDTAGFGDNRGAIHDICAAVSLGEVFKDSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKNSITFFISKSFLGRTEKQIYNVIKRKYEQLCEASDSNMSDSNSNIK
                     EKAWLFEEMLKDDGKNIHICNPLASDDREGLLRQVLELEEVKDKISAFQYPISADALL
                     VLDTLIKEIQDNIVSSLEDYVKAYTEDFISAVGSITMIEEIAKYDDVVEVFKNWLEST
                     TSPTIGRFINELARQSSLFLQDSCMKLQKNIKENLDIIDALSEYTEHGTSEILLSSVH
                     MEFIIEKTSKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNRENLMEVANKKDYKYS
                     VNDFNSILTNVTVTQKEELEDSITRLNAYGEEGNEIIREFISKYILNPFIVKTININD
                     KQGIEIRALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKNTIYMDDNLGMDFASEKNI
                     IIACNNLDVGSNVKINVSGKSGELVDNSMYGKNGEDGRDSGNIYLYIKEEIRNYRLTL
                     IANGGNGSKGIDGKNGETGASGSNGADAGYTSSFHGKMFKGYFAQGTSGGKGEKGGAG
                     GNAGRGGNAGKKGNIYFISDSEEQKNRIINRCDITVRDGEVGPNGRPGSGGYGGNGGY
                     HGYNTLSFSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPGREYAE
                     YGDRGADGGFNAPNTKISTAVSKIEDNFIKEKYQCYCSEI"
     gene            28204..33414
                     /locus_tag="PC592_001973"
     CDS             28204..33414
                     /locus_tag="PC592_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF4055947.1"
                     /translation="MANKLYSGIVNLLEDGRDELRKYNLEKKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDAETGQVYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRYTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKALISNVTEEKIRNILNKTKEDLDGQEIDYDGCKELIYL
                     LDVMLSDSVSIELCNPLDKNPEKLLDKMKNLPETFEKTNLGLMLTASCKIEIQKAVDV
                     TYKELEKLLVPYIESVKKGMEDSISTLSSINSLKDKKIQLDRMYTDLCGRANSMKELM
                     EFVQELSYGDGMQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYKEEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLIK
                     IISGYKLDILSSIYMYGDCELKIDCSMEKDVFSGKNIVLLTEKVFIPEGSYSINVSGK
                     NAEKLAGEDYIYNGMNGRNGNNAGTSGDIILSFKEIEKIGELKLYVDGGRGGNGQDGK
                     IGETGLTGKAGENAKIGSKKESKEFAKDKDTKYYLVKAEKGKQGGTGGIGGNGGNAGL
                     GSKAGQVYLLGKATLLKGAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GISAPIDDSDRNYYYFDRYVFNHASDEKEVADDGVKLNALYEKHKDWTISKREDSGSV
                     GAEGKDGLSGDTLKEKELLKQEHSLSIDTFFYEFFERFGFSGSKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYGFEKKNKAVLSLDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFIGEKQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKILKELEEGKKDELKEGYFNTYKESILTQIESGNQQIAVLKNELENK
                     MLSVNAKMNLLIQEIIKIKEDEKEDIEKLKEKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEGKRDKFDQIKEIIVKSIDDDNYSDKDDDIQRAKDGLSESE
                     YEEIYTKIQKKEIGLLEANYNNKQQKDKLAALEKSKQTIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLKVKSDFESKIEVIKDAIKGKEDNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELITKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSGSGSQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVVNQAKEQNRQIKEFLDQDAYQWQ
                     KTDNHILKVALAGSLDGKSRVGFENTYSIYDCNEEEVKKLLTGDEISFEVPLNQNFDA
                     IKYVTMYANIPNLRRNILDDSLKVKVHIHLYDSGYFSLYDDKKDTYYQYVFPQNYIDI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKKAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DLLTNEQKKKLESYFDKSSKYAWSESIDILKSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVNLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIID"
     gene            complement(33666..34177)
                     /locus_tag="PC592_001974"
                     /pseudo
     CDS             complement(33666..34177)
                     /locus_tag="PC592_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888383.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
     gene            34312..34500
                     /locus_tag="PC592_001975"
     CDS             34312..34500
                     /locus_tag="PC592_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055948.1"
                     /translation="MNKNDNLVIICMFIGMILGVAIGYVMGIYKGSVGTTMCYGLVFG
                     MLIGICIGAVIKNSNKKE"
     gene            complement(34670..35110)
                     /locus_tag="PC592_001976"
     CDS             complement(34670..35110)
                     /locus_tag="PC592_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF4055949.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKNGYARLCKLETYLETQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVMIQIGDKQVPAVEKMLISLTPKA
                     KEHWVTRYPCGNNGGWIRCRILEDADLLDIIQYIRAKKAPPKQN"
     gene            35445..36758
                     /locus_tag="PC592_001977"
     CDS             35445..36758
                     /locus_tag="PC592_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HDF4055950.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEENIEDIEPYWVCLPMATRTAV
                     GSYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRASESLQRYCSIVNKQYGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGIAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVRLPYGHTWKSFTYFLLDTLPENIRNNYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            36776..37312
                     /locus_tag="PC592_001978"
     CDS             36776..37312
                     /locus_tag="PC592_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDF4055951.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRIMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEIDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDVEEEN"
BASE COUNT        14313 a         4221 c         6375 g        12487 t
ORIGIN      
        1 gcaagtataa atatactaaa agaaggatta agactaataa caattcaaaa taaataactt
       61 atgtaagaac cgtaggaact atggggatgg cctgtggaga attagtaaga catattttag
      121 tatgcaaaat tctatgaagc aggaaccctg tgactttagt catgggaggt tcaggttagg
      181 ataaaacttg aaaagccaaa gacttctaaa agttttaaag agagtataga aaaactacat
      241 aagtatgagc cagatttgat aatagcagtt ggagctagat ttgcagagcc aattaaagaa
      301 gctgctacta aatattccaa acagcaattt gcaatagttg actatactta taaagttcag
      361 ccagctaatg taatttctgt atcatttcaa gataatgcta ctggatattt agcaggactt
      421 attgcaggta aaatgactga tactggtaaa gtaggtttta taggaggggt tgagggttct
      481 agtagagata agtatgaatc tggatttaga aaggggctta aaacttcaaa taaagatgct
      541 gaattactag ttaagtattc aaatatattt gaaaatcctg aatcagctag aactattgca
      601 aaagaaatga gagattctga tagagatgtt gtattttcag ctacagaaga tgatagcaaa
      661 agagctattc aggtggcaag agaaaatggt ggtaaagtta tagctattaa taaagaccaa
      721 tacgatatgg ctccaaataa tgtaataagt tcaattataa aagatgtaga gcaacctgtc
      781 tatgaactga taaagaatgt tgtaaaagat ggttttaagg gcaataaggt aatggaattt
      841 aaaataaaag atggagaact tggtttgact tcaaagagta gtagaaatat accaccagat
      901 gttttggaat atataaaaaa agagtataac aaggtgaaag atacatatta attattgatg
      961 tagaagatta taaaaatata ctttattaag tttagattaa ctatataaaa ttataacaat
     1021 aagtgtgtgg gcagaaaaat tctgctacac actttattta tattcatata aaaaaattat
     1081 caaaaaaaag aaaaaggagt aaaaaatgga atttacaaga gaaccattta tactagatga
     1141 cgatttgtgt ctagctttgg tggacaaaag aattagttat ctaatggaaa atgaattaaa
     1201 attaagaaat atagagataa taaaaacagt agaatgtaaa gaattatatg aaagcataaa
     1261 atatcaccca gatatatgta tttgtaattt aggaaaagga gatataattg ttgcgccgaa
     1321 tgtatataat caatacaaag agttattaag tagatataaa tttaatataa ttaagggaga
     1381 agctaattta ttaaatagat acccttatga tataccttac aatattgcga tagttggtga
     1441 ttatgctata cacaatttta agtatactga caaagcaata ttagattata ttgaaaataa
     1501 taaacttaaa aagataaata tagagcaggg ttattctaaa tgctcaatct gtatagtaga
     1561 tagaacatct ataataacat cagataaagg tatttggaaa agtatgaaga atacagaaat
     1621 agagtgttta ttgatagaaa aaggtcacat aaatttattt gagatgaatt atggatttat
     1681 aggtggatgt acagggttga tttctaagga taaactagct ttttgtggag atgttaaaaa
     1741 acatcctgac tatgaacgta taaaaagttt tgtagaaagt aaaaacaagg agatagttac
     1801 acttagctgt gaaaatttac tagatatagg ttctatagtt cctctcatga caagaaagga
     1861 gcgataactt tggttgagaa ggataatatt tcttccatga aatttttgag gaataataat
     1921 gtaaacgata gattaatata tacgaatgat attgtagaag tagtgataga ttctgcaaag
     1981 caagaagtat taaataaaaa aatacttaat ggtactaaag ctgaacaaag agctttaaat
     2041 attgatgaga tatcaacgga aataactagt atgataataa gtataatgaa agagaaactt
     2101 ttgaaagaat acattctaaa atgctatggg cgtacatatc ctgaagataa aaataatata
     2161 tacatatatt cactgaacat atttgctaaa aaagagattt ttatgagaga aacagtattt
     2221 acgagggtga gaaattatat agaagaaaat gattttataa atgtagaagg ttttattaga
     2281 tttagaatga gagaatttat gaaatatatt tctgctatag gtgatattgc agttgaagag
     2341 tatttaataa agaaagacca agatgaattt ataagagttt taaaatactt tatagatact
     2401 caagaagaaa agattgattt gcttaaagtt catataatgg aagacaatac atttgtttta
     2461 tacgataaaa atggaaataa gatagatagc atagatgatg aagaaattat aaatatggta
     2521 ataagagaaa atttaaatta tgaggacttt ctaataagta ccttgttaac tctatgtcct
     2581 aaaaaaatag aaatattgga tttattaaat aataattgct caaaggaaat tatagatact
     2641 gtagaagcaa tttttgaaaa taaagttagt ataattatgg aaaactagaa tctaggtgta
     2701 taagagttag ccatataaaa ctaaaaaaat tctttttaaa tcgacacaaa agacttataa
     2761 ttgtatataa agcatagtat agctagagct attaaatata aagaatatct atttgattaa
     2821 tgcaatatag cttgcaaata tacaattgat aaggagtaat tttataatgg ataatttaat
     2881 taggatactg atattagctg ttattggtgg atttataggt tatgttacga atgtagttgc
     2941 tataagactg atatttagac caatagagcc tattaaaata cctattttaa atatagaaat
     3001 agtaggtctt ataccaaaga gaagggtaga aatagcagca aatgtaggag aaataattca
     3061 agaagaattt ctttctatgg atgaaatact tgcaaatatc attactgacg aagacaagga
     3121 agaagttgta agatacataa aagcaagggt aaaaattata atacatgaga aagtttcatt
     3181 tatcccaggt ggtataaaaa acatgataca agattatcta ggagagataa ttgagtctga
     3241 agttaagaaa agtatagatg aattgagtaa aaatataata aataaagcaa atgaacgtat
     3301 agatatacaa aaaatggtcg aagataagat taatgaacta gatttatacg aattggaaga
     3361 gataataata agaatagcta agaaagaatt aaaacatata gagttcttgg ggcttgtctt
     3421 aggtttttta ataggtatag ttcaagggtt agttactatg tttatttaag tatatgatac
     3481 ttattgacta catttaggta ttaattgtat ttacttattt gattgtatta cttattaact
     3541 gtgcttaagt attaattata tttatttgac tgtagtacct attaattgta tttacttatt
     3601 taattgcgtt gcttattaac tgtatttaag tatttactgt attacttatt aactatatta
     3661 aatattgatt gtatttaagt atacaaaacc taaaagagta caataattag aagttagttt
     3721 taataaaaat tagttttagt atttatctag tcatatctat catgcatgtg gatatgtttt
     3781 aaaaatttta aatttatgaa aatattataa tatcactata aatcaagaga ttgatttaat
     3841 ataaaaatat aagaatattg gtttacagat gattgagatg aaaaataatg ggtaattaat
     3901 atattacatt aatgttgatt gatgtataac tatctgttat aatgaaaata tattaaaaat
     3961 catagtgttg aagaggaaga gtagagtaga aaccattctc agagaatttg ggtctatggc
     4021 tgagagccca tgtaataggt ctatttgaaa actaccttgg agctgagctt tattagcagt
     4081 atttgtattt atactatatg tgaaagtgct cgggtgacga ccttatagtc atcaagaggg
     4141 ttgtatatac ttgtatacgc caacttgggt ggaaccgcga attaatatcg tcccaaatat
     4201 atttggggcg attttttatt acaaaaaatc taaaaattat ttcaataagg aggaaaaaac
     4261 aatgattaaa gttgctttaa aagatggctc aataaaagaa tttgaaaatg ctatttctgt
     4321 tatggatgta gctaaatcca ttagtgaagg attagctaga aatgtggtag cagcgtctgt
     4381 gaacggagag gttgtaggtc tggaccacat tatagatact gattgtgact tgaatttatt
     4441 taagtttgaa gataaagaag gtaaggaagt ttttagacat acatcagcac atatattagc
     4501 tcaagctata aaaagacttt acccagaagc aaaacttgct ataggaccaa gtatagaaaa
     4561 tggattctac tatgatatag atttagacca tagattagtt ccagaagact tagaaaaaat
     4621 agaagctgaa atgaaaaaaa tagctaaaga agatttaaaa atagagagat ttgagcttcc
     4681 tagaaatgaa gctttagagc ttatgaaaga acaaggagaa gattataagg tagaactaat
     4741 ttctgattta cctgaaagtg aaataatatc tttctacaag caaggtgatt ttactgattt
     4801 atgtagagga ccacatttac catctactaa aaaagttaaa gctgttaaat tacaaagtgt
     4861 agcaggtgca tattggcgtg gtgacgaaaa taataagatg cttcaaagaa tatatggaac
     4921 ttcttttgag aaaaacaaag acttagaaga atatttacat ttactagaag aagctaaaaa
     4981 gagagaccac agaaaattag gtaaagaatt aggattattt atgatacctg aagaaggtcc
     5041 aggattccct atgtttttac caaaaggtat ggaacttaaa aatgaattat taaaattctg
     5101 gagagaaata cacagaaaag ctggatatat tgagatagaa tctccaatca tattaaatag
     5161 aaaattatgg gagacttcag gacactggta tcattacaaa gaaaatatgt atacagttaa
     5221 aatagatgat gaggattatg ctataaaacc tatgaactgt cctggtggat taatttacta
     5281 taactctcaa ctacattcat atagagattt cccaatgaga gttgcagagc ttggtagagt
     5341 tcatagacat gagttatctg gtgcattaca aggattaatg agagttagag catttactca
     5401 agacgattca catatattca tgttaccaga gcaaattaag gacgaaataa aaggagtagc
     5461 taacctaata gatggtatct acaaaacttt tggatttgaa tataatctag aattatctac
     5521 aagaccagag aactctatgg gaagcaacga agagtgggaa gcagcagaaa atggattaag
     5581 agaagcttta gaagaattag gtttaccata tactattaat gagggtgatg gagcattcta
     5641 tggtcctaag atagacttcc atctaaaaga ttgtttagga agaacttggc aatgtggtac
     5701 tatccaatta gatatgcaac ttccaagaca atttgataat acttatattg gacaagatgg
     5761 tgaaaagcat agaccagtta tgattcatag ggttgctttt ggtagtatag aaagatttat
     5821 aggtatatta atagagcatt atgctggtaa attcccagtt tggttatctc caactcaagt
     5881 taagatactt cctatatctg ataaatttat ggattatgca aatgaagtta agaaagaatt
     5941 atttgataag ggtataagag ttgagttaga tgatagagct gaaaaaattg gatttaagat
     6001 aagagaagct cagcttgaaa aagttccata catgttaata gtaggtgaaa aagaagtggc
     6061 tgataataat gtttctgtta gatcaagaga taaaggtgaa ataggtagta ttaaattaga
     6121 tgaatttata gctagtattt caaaggaaat tgaatcaaga gaaagtatta ttcaagacta
     6181 gtatacaaga tattagtagc taagatatta ttatataaga taaatttaat caatatgttg
     6241 atatatagtg attaaattta tgaaaagatg agtataatta gaggtacagt taatcatatt
     6301 tttatgatta atgtacctct agtttttttg tatggtagat ttattaataa atatatcata
     6361 gaagtgtttt gaatctggaa attttaaata aaaacttatt ttttgagtga taattaagtg
     6421 cttgttgata aggctatggc tgtaaaaatc ataaccttat tttcatattt gttccatttt
     6481 catgaaaatt attatccatt taagaaaatt tcttaatcct tttgaaatat ttcattttta
     6541 gtctagactt aaatttcttt cttcaaaata aatgcttaaa tgaattaaaa tttaggttta
     6601 ttttctaatc ttatgagtct atttttcata aataattacc ttataataga agaagttatg
     6661 ttggggttat gtgctaaaaa taacagcatt gtcaatgatt aattaatatt ttatgttatt
     6721 tttagattta tcttctatac atatattaat ttatttaact ttagttatag agagaatgtc
     6781 gagtaaatac acagacatta gagtctaaga aggtgtttat ggaacaagag tttttaaaag
     6841 agatagctaa ttagtttaat gtcaaaaaat gataaataca aaagaggaaa aagagaggtg
     6901 tttaaatgat agaaaaagta ggagaaaaat ctaagattat taaaacatca aaagaatata
     6961 agcgaactat aattgaagaa aaagatagag aatggactca aaaattaaac gacatactta
     7021 gtagaaataa tttttctaat gatgaattag acaaaatcaa ggagttaatt ccaaaagaga
     7081 ttttgactag tgaaaatgtc ggagaagttg tgactgaaga tggatatgct agacctgaat
     7141 atgatgaggt atttaaatca ttgttcactt taaataatga atacggttta cttgtaaatt
     7201 ttataaatga tattctaaaa gatgctccat atgctaacag gaatatcaaa ccgtttactc
     7261 aaataaagag aataattaga cttgaaactg acccaacaat taattacatt ggagagaaaa
     7321 ggcctagact tgatattttg gctgaagatg aagaaaataa tcatataaat attgagatgc
     7381 aaagagcttt tgaaaatgat tatttggaaa gagctgaata ttatcttagt cgtgtacatg
     7441 gtagaaagtt agaagaaggt aaagaatata aagaaattgg aaaaactatt ggaatacata
     7501 tactaaatca tgtaaaatat aatcacatag aagattatgt aaattgcctg agattaacaa
     7561 tggatgggca tccagagatt tattctagta aaactgcatt atattttata gagcttccaa
     7621 aaattcataa atctgactat atagtaaata gaattatgct atggggaaaa cttattatca
     7681 atccttctag tttagatgta agggttatag ctaagaatga ttctattatt aaaaaagcac
     7741 ttgatagatt aaaagaatta ggtagcaatg aagaatattt attaaatctg aaaagaggtg
     7801 cttatattat gaataaaagt agaaatttta aagaagagat agaaagagag acagcaatta
     7861 gagttgcaaa agaaaaagat tataaaataa ttataatgtt gaaaaaaaat ggttttaaat
     7921 tagatgatat attaaacaaa tttaatgctt ttgacttaag cgaagatgag ataaaagaag
     7981 tttatgaaaa taattaatgt ataaataaaa agtgaactta tacaagttca ttaaatctga
     8041 gtctggaaat atatatgtgt attttttaaa taaaaattta ttttaaagac cataatttag
     8101 aggtacagtt aatcacactt tcatgatact gtacctctag tttttttatt gtaaatttat
     8161 taataaatct acaataaaag tggttttgtt gtaataatca ttatatataa tgattatttt
     8221 ttatagtgat taaattttca cttgtagtgc ttaaatataa atttgtaaca ctatttttat
     8281 aaatgtataa atcactatga cgattcaact caaagtcact gtacaaaaca ccagaaacct
     8341 tatatcaata agatgttatt gcaccagatt gttcaagtct acgaaatgct gtatacaaaa
     8401 tagcttcttt caactcatac aatcctttgg ttttttcaag tatagattta ttaatctcat
     8461 aactatagct gtctttttta agtaaatgtt ttaagatact tgtttttgta tcacatctta
     8521 taacatcaga tgcgattgtc atgaatatca catccgatta aatatataat agttttatgg
     8581 actttgctta tcaaggtata tcatgaaaaa gacattttat tgtaatattt ataagatttt
     8641 atatggaaat aatgtaaaaa ctttataaat aatatatttt atacctagtt atagataaat
     8701 ttatatagtt attattaaaa aaaacaataa aaagtttaat tcaatctagc aaatttagtg
     8761 atataattaa aaaagaaaag aaatatggat ttatttggaa taattttgac aatctattta
     8821 ctacacgtgt agagtcgtat ataattaaat tatacataaa atataaaaaa ataatttagt
     8881 aatacgttag gagaaagtat tatgataaag tcaagcttat tttggaatat tttcattgcg
     8941 atatccttta tgatagaatg gtttctttgt aagaaaatgc tagattatac aagtgagaaa
     9001 aagatttcta acaaaaaaat aaacttttgt atagtaggta ttattgtttt tgctaacata
     9061 atctattttt ttgatgcacc tctaaatata agagtaatta tatctatgat agttactatt
     9121 gcattttata aaatttcata tgatgttagg tttataaagt ctgtattaat atccttaatt
     9181 tattggatgt tactaatagc tatagatgct ttgagtatat ctttaacagt ttggcttaat
     9241 tctataaatg acatgagtaa tatggggaca ggagatatat acagaattga atctataata
     9301 ttaggaaaga tacttttgat ttcggctttg tttttatata gagccttaaa aataaaattt
     9361 aatatagaaa taaataaaag gacattattt tatatagtta ttcctatagt cgctaatata
     9421 gcatcttttt ttgtcatttt taaatacata tttaatctaa agtttggtaa cttaatacat
     9481 aatttccaat tcgttgtgat ttctgttgta ttacttgtat caagcatcac tttgatttta
     9541 attgctaaga aattacagca atataatact ttagttgtag aaaataatat gattaaaaat
     9601 actttgaaat gtgaaaatga gtattatgaa gatatagaaa agaaatattt aaaaactaga
     9661 ttactaagtc atgatatgaa aaatcatata ttgtgcataa atgctatgat taaaaaaggt
     9721 attgatgtta cttcttattt aaataattta caggtagaaa tccagagtaa tgacttatta
     9781 tttaatactg gtaattttat attagatgct atattaagtg aaaagaaaga agtttgtgat
     9841 aggaatgata tagaattaaa aataggaata aattttagtt gttgtgaagc tgttgaatta
     9901 gtagatatat gtcatatatt ttcaaatatt ttagacaatg ccattgaggc atgtaataaa
     9961 attgatagtg gaaatagagt gatttgtgtt aaaggtgata ttatgcaaaa tttttatcta
    10021 ataaaagttg aaaatactaa gacgaataag attattacta aaaatggaga tattttgaca
    10081 gacaaaaaag gttctcttca tggacttgga ataaaaagtg taaaaaactc tgtaaataag
    10141 tatggtggga atgttgtaat tgaatatgat gataaaaaat ttgtagttaa aattgctatt
    10201 ccacttagaa atgtgaagaa agtggttaat aatataattt aatatatggg agttcaatat
    10261 atataaattt gatacgtaga agtttaatgt aaaaattttg tgtataggaa tttaacatac
    10321 atatttattt taatatatat tgaaggtata taattaaatc atataatgac atttgcagtt
    10381 tgaaattatt tattgagtat gagaaatttt caaggtcaga aagtttatga ctattatata
    10441 ttatattgtt tgtcgtattt attatagatt atataatgag tttaaaatat taaactttta
    10501 attttacaaa atataaaaag aagttgcatc aaaaagataa atgctcttta aagatgtaac
    10561 ttctatggta tatgtatgag gagctatatt gccatttctg gaatcaagct tctcatagct
    10621 tctatagttg tttggataag cttatcaagt tcccatccaa gcatttctgc accacttctt
    10681 atgacatctc gagagcagcc agcagcaaat gatttatctt taaatttctt cttaacagat
    10741 tttaattcta aatcagaaac actctttgaa ggacgcatta ttgcagctgc accaattaag
    10801 ccagtaagtt cgtctacagc aaacaatact ttctccataa attgttctgg tttgacatct
    10861 gaaccagtta atccatatcc atgacttatt gtagaatcga ttattgattt atctaaatca
    10921 agctctgtca ttaattctct ttgtttaaca caatgttcat caggatacat ttcaaaatct
    10981 aaatcatgta aaagtccaac gatttcccaa aattctactc tttcagggtc gtactccttt
    11041 gcatagtatc tcataactcc agatacaatt tgagcatgtc ttatatgaaa ttcttcctta
    11101 ttgtattttc ttaatatttc ccatgcttgt tctaaagttg gcatgtaact catttttatc
    11161 actcctctag ctgaatattt tgaattttta taaagtttat tttccattga ttatatcaat
    11221 caatttccaa aacgtcaaca tactgataca caattttgca gttaaattca gaaattagtg
    11281 aaaattaaat ctttaggtct aaattctttg tatctaaagt ttttcgtttc ttaatgttat
    11341 ctttgatata aatgctataa ttaaggtaat aaatccaact cctagtataa taatgtacac
    11401 tctatctgat aataaatcaa aaagtttacc atacataacc tgaccaagag gcattgcaat
    11461 tgttgttcct gcaaaaagaa ttgacattac ttttcctaag agttcatttg gagtttttaa
    11521 ttgtatgatt gttatagcat atattgagat aagagtcgtt gtaaaaaata ttagcataga
    11581 tgatacgata aaaattaaaa acggaactgg aaatcccgta tttaatataa atggatatac
    11641 tgaaaatgcc attggtatga acataagtgc acatatagta aaggaaatgt acaaattagt
    11701 gatttttaga tattttgaga aaataccaat actaacagca gctactagag aactaaaaga
    11761 aattgctccc tctgctagac catataagaa gttactagct cccatagtga tttttactat
    11821 atatggtata ccaacgatta acatagagct taaaaataag tttattgcta tagctaaaaa
    11881 aagtattttt agtataaatc tattttcttt acatatatga acaataccat catttatatc
    11941 aataaatata gtttttataa tgttgctggt ttgctcttgt ttgataaaag gaatctgtat
    12001 aaatatctcc ataattgcag atagaaagaa acttacacaa cttataacta taattgcatt
    12061 aattccaatt acaccgtaca agacacctcc caatacaggt cctgcaatat ttgtaaggga
    12121 tgcaactcca gctacgatac catttgcatt cattaaatgc tcattatcaa ctaaaagagg
    12181 tgtacttgac tgaacagttg gttgatacat tgtgcttatg actgataata tggtcataat
    12241 aattcctaca agtaatattg aaccattatt gttgaataaa aagagtgcta agactaacac
    12301 tgtaatacta cttgaaaaat caaaaataac cattaagttt cttctgttga atatatcagc
    12361 aatagctcca ccaatagggg agaatattat aattgggatt gaagatactg ctagtatagt
    12421 agcaaatatt tctgctttac cagttatatc gagtatgtat aaagacaaag caaatttaag
    12481 tattgatgca ccaaataatg agattatttg acctaatatc atcaagttga aatttttatt
    12541 aaaagtattc aaagatttta ccatatatat acctacctat ctaagattat taaaacattt
    12601 acaataattg ctataatagc aattactata aggacttttt ttcttacttt aatacctaat
    12661 attattagaa atatagaaac gattatagat aacatagagt aaagtggcat gagctcactg
    12721 ctagggtcta caagttttgt gtggatattt agtttatcat ttattttgta aataacatca
    12781 tttagtcttt gtattaattc aatcatatta tcctttctag ttataaagaa atgtttagaa
    12841 aatttatttt aaattattac tcaagtatat gttctacaag attgtctacc ataaaatcaa
    12901 atacttcaat gtagtcatat ccaatatctt cttttagcaa taggcttgac agtagggcat
    12961 tgcaaacacc aaaggctttt tctttctcta tttttaactt gagattatgt ctttcaatta
    13021 agctataaaa actttgtaca ttgttgtatt caagttgtga aagcatctct ttaggtatct
    13081 tattcaataa agtgatgtaa tcagtattat ttggtgaata taagaatggg tttttatcat
    13141 ataatcgata caacatcttt aaggcttttg caaaaccttc tttttgaggc atgttaccta
    13201 atatttcatc tactgatgat ataagtctgt tttggattcc atttagtact tcaaaaaata
    13261 acttttcttt tgaatcaaag aatgtgtaga atgtaccctt tgcaattcct gattttgaac
    13321 aaagttcatc aatattagtt tttttgtatc catatttaga ccagttgatt tcacattctg
    13381 aaattagtct ttttcttata ttatcttttt ctatttctgt aaagctttta gccatattta
    13441 tcaatcctct ctgtatatac gtattatcta tgacttaaaa tgttttttaa gtcatagata
    13501 tatagtattg tttatttata aatttgtcaa gtgatttata ttatgagact tgtattaaaa
    13561 tttgatttga ataagtttca agcgagtatg ttatcaaaat agaaaagcgt agaaaaaacg
    13621 ttaactctaa aaaatttttc taggtaaacg tttataataa aaagaaatgt ttacataacg
    13681 aataaatggc tataatttaa atacacaaag ttatatcaga gagaggaata aaaatatgtt
    13741 taatgaactt agaacaaaag aaaatgtata taaaaattta ataaatggaa aatgggtaga
    13801 atctaattca agaaaaccaa tagaaattta ctcaccaata gataattctc ttgttgggaa
    13861 agtacaatct atgacaaaac atgaagtaga tgaggctata aaaaatacaa aagagagtat
    13921 aaaagtatgg gctgatatgc ctgtatataa gagagccaat atatttcata aggctgctga
    13981 tttattgtta gaaaatatag atgaaatagc taatatactg gtacttgaaa tagcaaaaga
    14041 catgaaatct gcaagggcag aagttgagag aacagcagac tttttaagat atacagctga
    14101 tgtaggaaaa aatatggagg gtgaagctat tagtggagat aatttccctg gtggaacaag
    14161 aaataagatg tcttatgttt caagagttcc attaggtact gttttagcta tatctccttt
    14221 taattatcct gtaaatttat caatgtcaaa gattgctcca gcacttattg gtggaaatgc
    14281 agtagtatta aaacctgcta cacaaggggc tattagcgca cttcatgtgg tagaaattat
    14341 gagaaaagct ggtataccag atggagtact taatactatt acaggtaggg gtagtgagat
    14401 aggggattat gttgtaacgc ataaaggaat taattttatt aactttactg gtagtactga
    14461 agttggtcag catatatcta aaatatctgg aatggtgcca ttattattgg aacttggtgg
    14521 aaaagatgcg gctatagtat tagaagatgc agacttagat tttgcagcta agaatatagt
    14581 gtctggagcg tattcatatt caggacaaag atgtacagca gtaaagagaa ttttagtaca
    14641 ggagagtgta gctgataaat tagtggaaaa aataaagcca ttggtagaga atttgacaat
    14701 tggaaaccca aaagatgaag tagttatcac accacttata gataataaag caactgactt
    14761 tgttcaaggt ctagttgatg acgcattaca taaaggtgca aagttgatag taggtaatat
    14821 tagaaaaaat aatttattct acccaacatt gttagataat gtaaatactg atatgaagat
    14881 tgcttgggaa gaaccatttg gtccagtgct tccaattata agagttaaag atataagtca
    14941 agcaattgaa attgctaacc aatcagagta tgggcttcaa tcatcagtgt ttacaagtga
    15001 tattgatagg gcattttata tagctgataa gcttgaggtt ggtactgttc aaatcaataa
    15061 taaaactgaa agaggtccag accatttccc atttttaggt gtaaaggcat ctggtatggg
    15121 aactcaggga gttaagtatt caatagaagc tatgactaga ccaaaggcag tagtggtaaa
    15181 tgttagagga ttgtaataaa tagagataaa gaataataga aataaaaaat aaaggagttg
    15241 tcttaaattt gattttttgt aattgaattt taagttcaac tcctttttga atttttatat
    15301 gctatttctt agtaattatt ttttaataaa tatcttaaac tttgagattg atgaaatttg
    15361 aacatgataa atatcttaaa tttatagtct tgttttctaa tgatgaagcc tatttctact
    15421 taaatagagc aatttctaaa atgaacattt ttatctcgag taccatatac aatgaaaaaa
    15481 attaaccttg acaagtgacc gatggtcgct gtatgataaa taaaaaagaa acgaccagtg
    15541 gtcgttaaaa ggaggtatca ctctatgcca aaaggaattg tgcttacacc cgaacaacaa
    15601 gcagaacgcc gagaaaaaat agttgctgtt gctttgagtc tcatggctga aaatggattc
    15661 caaaaaacat caatgagaga aattgcagtt ttagccaaca tgggaaagtc aagtctatac
    15721 gattttttca aaacgaaaga cgagattgtt gtatacgcag ttgagaaaga aatagaaaaa
    15781 actatccaac aagttcatag gattattgat gatgaacttt cgccacaaca gtgccttaga
    15841 aaaatcatgc ttaatcatct tagatttcca aagcaatata gaactgtact gatgtggtta
    15901 aatacagaat ctgattattt agaagaagag tatcgaaaga gacttaaaga tgctcgttat
    15961 gcatatcaag atattataaa atcggtaatt gataatggtg tgaccacagg tatctttcgc
    16021 aaaacggata ccgctcttgt gacacgtttg ttaattaact ccatgttatc aatcagctac
    16081 acgtcacgac tatcggatag ttcggaaaaa atgttggatg aaacaatgaa tatatttctg
    16141 cacggaatta tgaatgatgg aggtgaatga ttatgattta ttatgtttta ccactagaac
    16201 ataaacaagc aaccattgaa attgttggtg gaaaaggaat gtctttatca aaactattga
    16261 cagcaggcat ccctgtgcca gacggttttc atgttacgac tgcttcatac cagatttttg
    16321 ttgagacgaa ccatattcag tctcgaatta ataaactgct agatggtatt gattccaata
    16381 ataccagcca acttgaagat gtatctaaga aaataggggt gcttttccat aatggagaaa
    16441 tgccacagga agtgtcggac gcaattaaaa cagcttatga cggattaggg aacatatcgg
    16501 tggctgtccg ttcatctgcg actgctgaag atttacctga cgcttctttt gcaggtcagc
    16561 aggaaactta tcttaacata caaggtgagg atgaagtcat tgacgctgta aagagatgct
    16621 gggcttcctt atggacagct cgtgctattg cttatcgtgt gaagaataat ataaagcacg
    16681 agattgtcgc acttgctgtt gtagtacaaa agcttgcatt ttccgattca tctggtatta
    16741 tgtttacgtt aaacccaatc aatggtagac gtagcgaaat gattattaac gctgcatggg
    16801 ggcttggtga agcggtggtt tctagcttag ttacacccga tacaatcgta gtggataagg
    16861 actccgaacg aattatatcg tatgaagtgg caaataaaga gattatgacg gttcgtactt
    16921 cagaaggaac agaagaaacc atggttcctg aaaggttgag aaaaaaatat actcttactc
    16981 gtaatcaggt aatgcaactg atacagcttg gaaagaaaat tgagaagtat tatcaaatgc
    17041 ctatggatgt agagtgggca ctggaaaaag ataaattgta cattgttcag gctcgtccaa
    17101 ttactgttct gccaccggaa tgggtattgc cagaacagga tgttgtatac acaaagggaa
    17161 gtttggcaga acacttacca aatcctgtta cacctttgtt cgccacgctt ggtcttgaaa
    17221 tcgtaaaccg tgcatcggag cttttatgga tagatatgtt tggtaaaagt gcgaaaaaac
    17281 tactgccaaa aaacggggca tacacggtta ttaatggata tgtttatctt tctgctaaat
    17341 caaagccatt tttgattgct atcaaatccc tttccccacg ctctttacgt aggacactta
    17401 tgaacagcgt tgcacgctgg gaaacggcac gaaaaggata tgaggatgct attaaacaat
    17461 gggaagaaaa gcctctgcat acgatgaacg cacatcaaat tatggagggt attcagacaa
    17521 tattttatgc cgcatgtatt tatttcacaa ggattcagct tacgttgcct gctgcttcta
    17581 tcagtgaaac attatttaca aaattatttc aaggagcagt tcgccgtgct ggtataacgg
    17641 atacttccgt tttcctgctt gggtttgata cgattgctct gcaatcggaa aaggagttat
    17701 ggggtctttc agaatgggta aagcaaaata acagcatcaa cctttatctg caaaacagtc
    17761 ctgcaataaa gatagcagaa gatttcatgt cttcagttgt gcctgttgga gtttcacagg
    17821 aagtatggat agaatggaaa aatcgaatta ataagtactt taaagagttt ggtcgtaccg
    17881 cttatgaatt tgattttgcg tattccacac cacaggagac acttacacca acttttgaat
    17941 ccgtaaaaac atttgtggaa ggaaaagggg aaagtccttt tttacgccag accacgtttg
    18001 aaaagcgtag aaaacatgca gaagaagaga ttttacaaca cataggtgga ttgcgtaaaa
    18061 aactattttt taagttgctc cattgggcgc aggaaacctc tcctatgcgt gaaaatgcta
    18121 tttatttgat gggaatggga catcctctga ttcgctgtat gtttcaggaa atctcagaac
    18181 gattcatacg aggaggagct atttcacatt tagatgatat ttattggctc acaaaatcgg
    18241 aattggaggc gcttatagag cagttggata aaaataagtc tctatctgat atgaacgggt
    18301 taatacctgt tcgaaaagct gaacttaaaa aatacatggg ttatgtgtca ccatccaagt
    18361 tgccagagaa aaacaaaaaa actatatcac aagcactaca gaagcagaaa gatggtaaaa
    18421 ttgtgttgac gggtattggt accagtactg gtgttgtgac ggctccagct tgtgtactga
    18481 atagtccagc agattttgaa agctttcaac ctggaagtgt tttggttgca gttaccacaa
    18541 ctccagcatg gacaccatta ttttcatctg caagtgcgat tgtaacggac attggtggtc
    18601 ctcttagcca ttcaagcatt gtcgcacgtg aatatggcat tccagccgtt atggctacac
    18661 acattgccac acgaactatc aagagtggac aaatgataac ggtggacggg ttggcaggta
    18721 cggtgacgtt tgatgagtaa aaagcctatt ttcgctttga agctttcaac ctttgtgatt
    18781 gcgttagcgg aagtagtaat acttaaagtt ttgagattta atcatactac taatacccac
    18841 caaacagcgg taagaaaaac catagctcgg tgggtatttt cttatgcaaa aaaatgagag
    18901 tgtatcaaaa taaaaatttg attagaaaaa atcaattttg agacaattcc tttatttgtt
    18961 aatacaataa tatcacttat aataagcaat tttatattgt taattggagg agttttgaaa
    19021 cataagtttt tcaaaatctt ttattggtaa aggtctagag aacacgtatc cttgtaacat
    19081 atcacagttt atttcttgca agaaatcttt ttgaaaactg gtctctattc cctcagctac
    19141 agtggtcatt tttaactttt tagccagttc gattatagat acaattatat ctctttcacg
    19201 ttgagaatct aaatgttctg attgaaaaaa tgctctatct aattttaatg tatctacata
    19261 aatatcctta agcatattga ttgaagaata gccacttcca aaatcatcaa tagagcattt
    19321 aaagccattt ttatgaattt catttattat ttcactaaat actttgacat cttcaaatac
    19381 aattgtttct gtaatctcaa tttctataag gtgagaagga atatcatatt ttttagctat
    19441 tttatcatat gtcttgatga aattattgga tgaaaaatga taacgagaca tatttactga
    19501 aatatttata ggatttaatc catcatcaat ccattttttt aaagtcttgc aaacttcctc
    19561 aaaaacatat aaatccaact gtataataaa tccatttgtc tcaaataatg gaataaattc
    19621 gtttggagga attattcctt caacaggatg aatccatctt actaaagctt ctgcaccaca
    19681 tatggtttgg gtagataact ccaacttggg ttgcaaataa acttgaaatt ctcttttttc
    19741 aagtgcttca tacattctat tttctatgct ttgttctaga ataagttttt ccttatcttt
    19801 tttactatag aaattacaaa tacataaacc atgattttct acgtttttaa ttgatttaga
    19861 agctacattt gcactatctt ggatatttgt tatatctaaa gaagtatcat aaattacata
    19921 tgcaccagca gtaaaataaa gtatatattt ataatctgcg ttatcgttga acctattaat
    19981 atgtgtaacc attgagttca gtctagaagt tatatcttct ggtttatctt ttaaaagaag
    20041 aataaattta tcagcaaaga ttctggtaac caattcaccc tcatgtaagt gtttacttat
    20101 acagttgtag atatatttta aaagcttatc tccagctata tttcctgcta aatcatttat
    20161 taatttaaat ttttgcatgt tcaaccatat tagagtatat gtacccgatg gtgattgact
    20221 aataacttct tttgctatta tattaaactt tgtatgattc ataccaccag taacggagtc
    20281 aataaaagct aatttctcta attctttatt atttttttca ataatctcat tttgttttac
    20341 taatgttgtt acatctgaat atattaaaag atatataggt ttaccatctt cccaatctat
    20401 acattcagct acaacttgca tatgaacaat atccccattg atattttgtg gagaaacaga
    20461 aaaacaaacg tatttcccag ctttaaaatc actttgatat ttgtacacag cactaagata
    20521 actttctaaa tttatatcat ctaatagaaa atttacatta tctttgaaca tgtcaaagta
    20581 ttttttatta gcatcaagaa gttggaatcc aaagtcagta accttaaact tggcaatgag
    20641 acctggaaaa ttgttgtaag ttacagtttg ttctatttta atcatcattt gttctgtaat
    20701 atcaatcata acagagtatg aaataggata tccatcaacg acttctcctg ttaaaaatcc
    20761 aaataacttt atccataatt tttttccatt acggtgtttc atacgacaga catagtcata
    20821 tttttttgct ccggtggaga atgtcttttc tacatactct acaagttcat tccaatcctc
    20881 tggattatcc ttgtaaaaga ggtcgcattg attgtgaaat agagtttcgt actcttcttt
    20941 tgtatatccg aacatttcat aataacggtc attagcccaa acaacagtaa agtgttcatc
    21001 taataggtgt ttactaacac ttacatccag tgcattcatt aataaactgt attcaatatt
    21061 tgcaaaatct atatattttg acattcttag tactccctta taacatatat tttgtagaat
    21121 atctgaacta gctagtttaa agtagattta tttttaagct tattttcata catcaaagaa
    21181 tctgcctctg ctattaaagt ttcaatatcg gatattccat cccactcaac taatccatag
    21241 cttatggaaa gagcataagg atactcgtcg gtattactta attttgataa ttcataattt
    21301 atatcaatca ttattttttc tgcttctata caacttgtat cctgtaaaag gaataaaaat
    21361 tcatctccac catatctaaa cagtaaggaa ttttctacat ttataagttt ttttattatt
    21421 tttgcagtag tggatatgta tttatcgcca aattggtgtc caaagttatc atttacaagt
    21481 tttaatctgt ttaaatcggt aaaacataaa gtaaatttgt agtgatttga catccattct
    21541 gatagttttt gatttacaaa aggtctattg tagaagcctg tcagtaaatc tgtatataca
    21601 atatcattca atttattaat ttcatgttct gtttttatgc tttctaaata ttctagttgg
    21661 tttttaatat cataactttt tatttgagta attctaaaac tatatttttc tgcaatatag
    21721 ttacctacca aaactattat ggcagactta attccatata attttaaaat caatacattt
    21781 ccaacagtat aatatattga tagacttaaa catagataca agtacattac aaacataagg
    21841 cttaataaaa aatttagatt ttttttgtcc tctaaaactg tgtcaaaatt aatctgatta
    21901 tttttatgat ttttataaca gaaatataga cctgtaacta taaagctaga tgatatagaa
    21961 tatactcggt aaatatttgt aatgtaatta ctgtcaaata aatatgctgg catatctaat
    22021 gttattgaca ttaaagacct aaaaaatatg tttattgcca aaccaataat agaacagttt
    22081 agtgaataaa aaagattttt tattatagag gttttgtaag ttattttaat ttctatgaat
    22141 aaaatcaacg taaaaatcgt ccaatttata attagatgta accttaaata agtacaaata
    22201 ataaaaatta aataattaaa cagagagtat ataatatata ctttatattt atttttagag
    22261 ttactaatca ttatatcgag atatttaaaa aagttataat gataaaggta ataagataaa
    22321 aaacatatta aaattataag taatctcata tacatatcca ttttagttac tgttcctttt
    22381 atgattattt tgtttattag tgtacatcct aatatcagca atattaataa tttcttctac
    22441 agtcattttg ttttcgctag gaacttccac aataccatag ctaaaagata tcttattata
    22501 catactttta cgtattttct ctataaattc ttttgtagtg ttttcattag atttaggcat
    22561 aataactata aactcatctc ctcctattct ggcgaatata tcatctgctt ttaaatttga
    22621 aataattata cttgaaaagt taataatata gttatcacca gctaaatgtc catatttatc
    22681 atttattgtc tttaatttgt ctaaatcaat atatatcaat gaaaataata aactattatc
    22741 aatgtaatgt tgtatttttt caaaagcaaa ttttctatta tatgctgatg ttaattcatc
    22801 aatgtttgct tttttcttta ataaattgac ttttaataat tgttcttgct ttatcatttt
    22861 tagtctatta tgttcttttt ctaaataaat atttttttca atggaatata tatgattgat
    22921 gaatataatc atttgtaatg ataataatat gttacttcct aatataaaat aagaagttaa
    22981 agcgcttggt ggagaaaatg caatttgtat actatcgaat aatatatatc ctaaagtgaa
    23041 gtagataaac tttaaaaata gactaaattc tatttgattt tgagttatta cataaatatg
    23101 ctcttttatt ttatccatag agtaccataa gataaaatct aaaatagaag ctattaaaat
    23161 actaattatc ctagatgaca tatttacaaa tattatatct ggacttgtat tttcgacaat
    23221 tgacattata cttatagtaa taagatgtaa aatacaaaaa tttattactg ctatattagg
    23281 aataaagtgt ttgttatcag aattttttat gctaattaaa agcaatttat gacttactat
    23341 atagaacaat atataaaata gtggtaatgg caattttgtg aatattattg ttaagaaagt
    23401 tagtggtttt attaaaaaaa tatatttata attcttatgt atagctatac ttttatttcc
    23461 aaaagatgct atcttgtaga tgtaaatatt acatagttca actattaata tgatagttat
    23521 gattaaaaat atgtggtatt tcatagtaca tcctctttta aaatgaaatt ctatttactt
    23581 aaaatagatt agattttata tactctattt tacagttttt atttaaatac atgtaaagaa
    23641 cttatggata tttttttatt gtgtatgatt gtgttagata aagtttgaaa aatatctcta
    23701 tatcttacat ttatacatag taagtatgat aattatacag taagtattat atgatttatt
    23761 atgtaaaata agtagagtta ttctatcaat aaatatacat aatatgctaa atatatatat
    23821 tttttactga aaatttgaaa tacttaaaat tgttccagtt aatacactac aataatatgt
    23881 taacttattg tagtatgact atagtatgct attttactgc attacagtat tagaaacctt
    23941 agactacgga tataaatggt ttatattaat tatagattat gaagaaaaaa taagcaacta
    24001 ttttgcttta ttgaataaaa gtaagtataa cttacaaaaa ataataaatt tattttacta
    24061 aataggaaaa atataaagaa aaaaactaaa atttgattat ttttgaacat ataattaaac
    24121 aaatttatat tggtaaattt acacacagaa gatagactcg attctataaa atttgctctt
    24181 aaatgacagg gaatatgcca caattactat tgaggagata gtacttttac tatggaataa
    24241 gatagattat atagctgtag ataaaataaa aattgtttaa gacgtttaca aaataattgt
    24301 gaggagtgta aggtttatct agactttgtt ttgtaaaata gcagattata caagaattta
    24361 tatgtgaata aatttaggag tactataaaa aataataaag tttttatatg attttaaata
    24421 aattaagtta agtaatggat attttctaag tataataatt gaaaatatcc attgttgtat
    24481 ttattatatt ttaaaaataa aatatgtttt gtattgtaga aaaatcttgt tatctataaa
    24541 attaagttat tttataagta tttttatcca gttatacgta tttattgacc agttatacaa
    24601 aaatattgaa tattaagaaa attagtacta ctatataaat aaatatatat atataaagga
    24661 ggttttttat atgagtctta ttgttggtgg atggtcaaaa tttagggctg tcgaagaaga
    24721 agatttaaaa gtatttaatg aagctgtagg aatgttaaaa ggggttgatt atgaaccact
    24781 tattgttgct actcaaattg tagcaggaac aaattttaaa tttatttgta atgctacttc
    24841 agttacaaat cctccgcatg attacttagc agaaataatt atttttaacc ctcttccttg
    24901 tgataaacaa aaagcaacaa ttacaagtat taatatagtt aagtaatatt aataggagct
    24961 ggaatatgag attaaatata actaaacaaa atacgataga ggttgaaggt agtaaaaaag
    25021 aagatgttta ttttataata gttgataatg ttttttttga acgcaaaggt aatgtattct
    25081 atagtatcac aaataataat ttaaataatt atgatataaa aatattacca actgataata
    25141 tttttctaga attaaaaata acatctacta aagatttaga acctgttttt attgtagctg
    25201 aagatagaca atacaatcat tgcagtgtaa tgtttaaacc agtaatggtg tagtgtttaa
    25261 tcaaataaaa ttaaaatatt caggctagta atggtgtgat atttaatcaa ataaaattaa
    25321 gatattcaac ccaatagcaa tgtaatgttt aatttaattg tagaaatata attttaataa
    25381 gaaagtctat atttataaat agagcaaaat agtgaataaa taatataaaa acaactgtag
    25441 tacataaagt acaataaaat aagttcatta actaaaataa ctgtgttgat aaattttata
    25501 ttatacaaca cagttatttt aatgaataga aataaataat tataaaatga aaatataaac
    25561 agattaaaaa caaaaaataa aaacaaattt aaatacagtc taaaaacttt acaatttacc
    25621 taagttatta aactttattt aaataagaat atataagcaa ggaggcaaat gaatgccaga
    25681 agataataaa acatttttat atgaattaaa agagttatta agtaacggag aaaaacaaat
    25741 agctaaagca ataggtcaag atttaatttt aattcttggt ggaacaggct gtggaaaaag
    25801 tactgcaatc aattatcttg caggatgtga aatgcataaa gtagaagatg aagatactgg
    25861 agtatcttac attacctgcg aagaccctgt agcagatatt ggttcaggag ctgtttctaa
    25921 aactttatat ccagaggtta tagatatgaa aaaaggcttt gaaggaatga ctgcaaaatt
    25981 ttgcgatact gcaggatttg gtgataacag aggagcaatc catgatattt gtgcagcagt
    26041 ttcattaggt gaagtattta aagattctgc atctatatgt gcagtaattg tcttgatacc
    26101 agaagcagat atattagatt ctagacttac aaaggtacta gacttgttcc aacagttaaa
    26161 tatgtgtctt cataaagaaa attttaagaa tagtataact tttttcattt caaagagttt
    26221 cttaggaaga acagaaaaac aaatatataa tgttataaaa agaaaatatg aacagttatg
    26281 tgaagcttca gatagtaata tgtcagattc aaatagtaat ataaaagaaa aagcttggtt
    26341 gtttgaagaa atgctaaaag atgatggcaa aaatatacat atttgtaatc cgcttgcatc
    26401 agatgatagg gaaggcttat taagacaagt actagaatta gaggaagtta aagataagat
    26461 atcagcattc caatatccaa ttagtgcaga tgcactatta gttttagata cgttgataaa
    26521 agaaattcaa gacaatatcg tatctagctt agaagattat gttaaggctt atacagaaga
    26581 ttttatcagt gctgttggta gtataacaat gattgaagaa atagcaaaat atgatgatgt
    26641 agtagaagta tttaaaaact ggttggaaag tacaacaagt ccaactatag gtagatttat
    26701 caacgaatta gccagacaaa gcagtttatt cttacaagat agttgcatga aattacaaaa
    26761 gaatataaaa gaaaatttag atataattga tgctttaagt gaatatacag aacatggaac
    26821 tagtgaaatc ttattatctt ctgtacatat ggaatttatt atagaaaaga caagtaagaa
    26881 gataatggaa caaaacttca ttataataag aaagaattta gaaaaagttt tagtttctta
    26941 tgaagtgcaa aaacaggtat ttacattacc aaatagagaa aatctaatgg aagttgcaaa
    27001 taaaaaggat tataaatata gtgtaaatga ttttaattca attttgacaa atgttacagt
    27061 tacacaaaaa gaagagttag aagacagtat aacaagatta aatgcatatg gagaagaagg
    27121 taatgaaata attagagaat ttattagtaa atacatttta aatccattta tagtaaaaac
    27181 aattaatatt aatgataagc aaggtattga aataagagcg ttaattccaa acttagtaat
    27241 tagtagtgta ttggaatatt tcaaaaatag aaaagtggat gacaatgttt ctacatttat
    27301 gttctttgct aaaaatacta tttatatgga tgataacctt ggaatggact ttgcatcaga
    27361 gaaaaatatt attattgctt gtaataatct cgacgtaggt agtaatgtaa aaattaatgt
    27421 aagtggaaag agtggagaac ttgtagataa ttctatgtat gggaaaaatg gtgaagatgg
    27481 tagagattca ggtaatattt acttatatat taaagaagaa attagaaatt atcgtttaac
    27541 actgattgca aatggaggaa atggttctaa aggaatagat gggaaaaatg gtgaaactgg
    27601 agcttcagga agtaatggag ctgatgctgg atatacaagt agtttccacg gaaagatgtt
    27661 taaagggtat tttgcacaag gtacaagtgg tggaaaaggt gaaaaaggtg gcgctggtgg
    27721 aaatgctgga agaggcggaa atgctggtaa gaaaggtaat atttacttca tttcagattc
    27781 agaagaacag aaaaatagaa taattaatcg ttgtgatata acagtgagag atggagaagt
    27841 aggtccaaat ggtagaccag gttcaggtgg atatggagga aatggtggtt atcacggata
    27901 taatacactt tcattttctc caagtggtat agataagact gtatactata caggatactt
    27961 tacaagttgg gattataagt tagatagtat aattaaatat catatagaat ttagtggtgg
    28021 aagttggaat gaaggtaaaa caggaccagg aagagaatac gctgaatatg gagacagagg
    28081 agcagatgga ggatttaatg ctccaaacac taagatatca acagctgttt caaaaataga
    28141 agataatttt attaaagaaa aatatcaatg ctattgttct gaaatataga aagggataga
    28201 tatatggcaa ataaacttta tagtggaatt gtaaaccttt tggaagatgg aagggacgag
    28261 cttagaaaat ataatttaga aaagaagtct attttattat ttttaggtgc ttcaggtgtc
    28321 ggaaagagta cttgtataaa ttatttaaaa ggttgtgtaa tggaagaaaa aacagatgca
    28381 gaaactgggc aagtatatat aactgcaaaa gattcggctg tcgaaattgg aaatggtgta
    28441 tattctaaga ctttatgccc agaagttgta gatattgcaa atagggattt ttcattatgt
    28501 gattgcccag gtttttttga taaccgtgga gcagagtata tgattgcagg tgctatgctt
    28561 gtaagggaaa ccatctctac atcttcaaag gtgaaaggga tggtagttat tttagactat
    28621 caatccctat tagactctag atatacatta ttaatagaaa cgggcaaaaa tttgaaagat
    28681 atgcttggtg attatgcaaa gtataaagaa aatttcttct ttcttatcaa taaaatacct
    28741 aaagcactaa taagcaatgt aacagaagaa aaaataagaa atatattgaa taaaacaaaa
    28801 gaagatttag atggacaaga gatagattat gatggatgta aggaattgat ttacttattg
    28861 gatgtaatgt tatcagatag tgtatctata gaattgtgta acccactaga taaaaatcca
    28921 gaaaagttat tggataaaat gaaaaattta cctgaaactt ttgaaaaaac aaatctggga
    28981 ttgatgctta ctgcttcttg taaaatagag atacaaaaag ctgttgatgt aacatacaaa
    29041 gagttagaaa aacttttagt cccttatata gaaagtgtca aaaaaggtat ggaagattct
    29101 atttccactc tatcttctat aaatagtcta aaggataaaa aaattcaatt agacaggatg
    29161 tatacggatt tatgtggtag agctaatagt atgaaagagc ttatggagtt tgtacaagaa
    29221 ctttcatatg gtgatggtat gcagaaagtg aatatattag aagaaacacg tcttctttta
    29281 gagttaaata gctattgcag tgagacccat attgttggtc taagtgagtt gttaaaatca
    29341 ttactaaaaa atactttaga agatacgtta aaagatatta aatattggat agcagaggaa
    29401 gaatataagg aagaagaagc caaaaagctt gaagatgcag aatataggat agagaagatt
    29461 caaagttgta catatataaa atcatatgag aaagaaaatg tactttctat atatattcct
    29521 atacctaaag tgaatttatc agatttgatt aaaataatat ctggttataa acttgatatt
    29581 ttatcatcta tatatatgta tggagattgc gaattaaaaa ttgattgtag tatggagaaa
    29641 gacgtgtttt caggtaaaaa tattgtattg cttacagaga aagtatttat accagaaggc
    29701 tcttattcaa tcaatgtatc tggtaagaat gcggagaagt tggctggaga agattatata
    29761 tacaatggta tgaatggaag aaatggtaat aatgcaggta cttcaggtga tattatatta
    29821 tcttttaaag aaatagaaaa aataggagaa cttaaacttt atgtagatgg tggacgtggt
    29881 ggaaatggac aagatggaaa aataggagaa acagggctaa ctggaaaagc tggggaaaac
    29941 gctaaaatag gttctaaaaa agagtcaaaa gaatttgcta aggataaaga tacaaaatac
    30001 tatttggtaa aagcagaaaa aggaaaacaa ggtggaactg gaggtatagg aggtaatggt
    30061 ggaaatgcag gtcttggaag caaggctgga caagtttatc tccttggaaa agctacttta
    30121 ttaaaaggtg ctataagtaa gaaagatggg aatcacggtt tagcaggaaa aggaggctct
    30181 ggtggtgctg gtggtgcagg aggtcttggt ggaattagag gtatctatga agaaacaata
    30241 agatatatag gcatctctgc tccaatagat gatagtgata gaaactacta ttattttgat
    30301 agatatgtgt ttaatcatgc ttcagatgag aaggaagtag cagatgatgg agtgaaatta
    30361 aatgctcttt atgaaaaaca taaggactgg acaattagca aacgtgaaga ttcaggttca
    30421 gtcggagcag agggaaaaga cggtctctct ggagatacat taaaagaaaa ggaactgtta
    30481 aagcaagaac attctttgtc aatagataca ttcttttatg aatttttcga gagatttggt
    30541 ttttctggaa gtaaaggtta tagaaatctt agactgttgt gtgcagtagg aattttagaa
    30601 gcggatattt tagaactttc acatatttat gaaatttttc atgcagttga gaaaatagag
    30661 atgcagttaa atagagaaat ccttcagaaa tactatggtt ttgagaagaa aaataaagca
    30721 gtactttctc tggatgatat gaatataaag aaagaatttt ataaagaggc aaaggaaata
    30781 tatgaatacc ttataaataa attgatgcag tctgatagaa tagaatcttt cataggagaa
    30841 aagcagaatt ttagtgaatg gagtatgatt ttatttgcac ttgaacaaaa aacagcattc
    30901 tatgtgcaga tgatagaaga aagtgaaatt ggaggaaatc gtgttacaga tattcgttct
    30961 ttgacagatt atctggataa gatcttaaag gagttggaag aaggaaagaa agatgagtta
    31021 aaagaagggt atttcaatac atataaggaa agtatcctaa ctcaaattga atctggaaat
    31081 caacaaatag ctgttttaaa aaatgaactt gagaataaaa tgctttctgt taatgcaaaa
    31141 atgaacttgt tgattcaaga aattataaag ataaaagaag atgaaaaaga agatatagag
    31201 aaactaaaag agaaacaggc aaaacttgag gaacaaatga aaacacaatt aattctttct
    31261 ggaatacaaa gcgcattgag tttattgact gcatttagtg gcgttggtca agcttgttta
    31321 ggagcatttg acagtgcaaa atctttgaag gaaaatcttt cagctaagga agaggaatac
    31381 caatggacta acaggatggt tgatttttca gattttaaat tggattctga tggtatgaga
    31441 tttgtacttg gagaacagtt aagtgaagat agaaaaaatg ctttagataa aatgacttat
    31501 aacttggcag gtgttgatga aggaaaaaga gataaatttg accaaattaa ggagattata
    31561 gttaagtcta tagatgatga taactattca gacaaagatg acgatattca aagagcgaaa
    31621 gatgggttaa gtgaaagtga gtatgaggaa atttacacaa aaatccagaa aaaagaaata
    31681 ggtttgttgg aagcaaatta caataataaa caacaaaaag acaagttagc tgcactagag
    31741 aaaagtaaac aaactattga aagacaacaa aagacatcta aaattaaaaa tgcattgagt
    31801 attggaagtt ctgcttgttc tcttataaat actgcaatta gtggtgttaa taattgtctt
    31861 aaagtaaaat ctgactttga aagcaaaata gaggtaatta aagatgcaat taagggtaag
    31921 gaagataata ttaagaaact agatgaattg aatactcaaa tggtggagtt taaagataaa
    31981 actttgaagg aatctgttat accatttgta gaaaaatttg atagtacagt taaaaatcaa
    32041 gatatttttg aaaatgagat aagtaaatta aagatgaagg aagttttaac tgaattaatt
    32101 acaaagtttg gaagtttaaa aatggaaaat tcagaggaga tttctataat atttaaaaaa
    32161 gtacaggata tgatggaaac tcaaattatt attactgata agattgataa gaagaaagat
    32221 aatcttgcaa tgggagaatt gatttatcaa atgtcaggta gtggtagtca aatgaatgaa
    32281 tatcagaaaa aacttatcca tcaaattgaa ttaaatcagg ttagatattt gtgtcaggtg
    32341 gaggcagcag cttttcaact atggacattt ccatttggaa gcaatatagt aaacatatta
    32401 aatagatgtc atgtagggat tacagaagat gaaaacgagg ttgtaaatca ggcgaaagag
    32461 caaaatagac agattaaaga gtttcttgac caagatgctt atcaatggca aaaaacggat
    32521 aaccatattt tgaaggtagc attagcagga agtttagatg ggaagtcacg tgtggggttt
    32581 gaaaatacat attctatata tgactgtaac gaagaagaag tgaaaaagct tttgacagga
    32641 gatgaaatta gttttgaggt tccactaaat caaaactttg atgctataaa atatgtaact
    32701 atgtatgcaa atatcccaaa tcttagacga aatatcttag atgatagttt aaaagtaaag
    32761 gtgcatattc atttatatga tagtggatac ttctctttat atgatgataa aaaagatacc
    32821 tattatcaat atgtatttcc acaaaactat atagacatta cacatggtct tgatgttaaa
    32881 tacaatgatt cagattcaat aaactcaata tggtcttcgg tggaagataa aggaattgaa
    32941 aagttcaaaa aagcaggatt aaactctggt agaagtccat attctatggc taagatttct
    33001 ttgaaggcac attttaataa gaagctttct tatgatttac ttacaaatga gcagaagaag
    33061 aaactagaat catactttga taaatctagt aagtatgcat ggagcgagag tatagatata
    33121 ttgaagagtc tagggtatat tgatttgaag ggaattttgt caaagagttg gtatgaaatc
    33181 aagaaagata tagatagtga tggagagatt atgaagcatt tttctatatt acaagttaat
    33241 ttattggaaa gaattattta tgaacagact agtatattaa aggaaaatat acctaatttg
    33301 acaattgaat tggtaggctg tggtatttat gtagagtctg aatttaatta tctaaagcaa
    33361 aatgatttaa aatgctatga agaaagattg gttgaaaata cgattattga ttgaaaatat
    33421 aactaataga taagttttaa aagaatttac aaaaggagat ttttcaaaat gaaaatttga
    33481 attatctcct tttttgtaaa aaatagaaag aagttgagtt taaaatttgt agaatatgtt
    33541 ttatataatt ttgattagaa aaaaactact tttaagacat cttcttttta aaggatgaat
    33601 tataaaataa aatagtattt gcacatgtta caccttcaag gaattgtata ggctaatatg
    33661 ctttataaaa agccgtatga aactattgtg tttgctagat gttcaagttt actctcgtca
    33721 ggagattctc atttttcgga tttctcaatc atagttacta tttggagaaa tctagtagca
    33781 tttgcttttc cttgagacac ataacaatat tgtattattc tattacagtt tcagaatata
    33841 tgtaagagcc ttcttttttg ttgacttcaa gaaattcact gtgtcaaatt gtatatagat
    33901 ttttttctaa tacattcttc taataattag tcaataccaa taagaaacat gactgaacca
    33961 gccatattta tatcctttct aaaaatagaa atacctatag cagaggcatc taaaatagaa
    34021 atttctaatt ttttatttag tagagaagag agaccttttt taaaatattt tatagagtta
    34081 agtgcgatta taaaaatttt aagtactttg ggaaacatat tttggatata cttttgatta
    34141 gtagtttatt tactaatttg tctctgtaat aattgttatt aataaattta taaaattata
    34201 tgacatttat accagtatat attagaatta aagaaagtta atttatagtt ctttgtttta
    34261 agttaagaaa ccgagctaag caatttaaaa tatatggaat ggagaagaag tatgaataaa
    34321 aacgacaatt tggttattat atgtatgttt ataggcatga tacttggagt ggctataggt
    34381 tatgttatgg gtatttataa aggaagtgta ggtaccacaa tgtgttatgg actagttttt
    34441 ggaatgctaa ttggcatatg tataggggct gttatcaaaa attctaataa aaaagaataa
    34501 ataaaacttt atttactagg atatttagtt acaatttatt tatgataaaa ttttttacgt
    34561 atatgcaaaa aatcaaataa ggcataataa cagatatttt tattattatt tttctacata
    34621 gaaagaattg aatttatata cactacattt aaattataaa aaataaaagt taattttgtt
    34681 taggtggagc tttttttgct cttatatatt gaataatgtc aagtaagtct gcatcttcta
    34741 aaatacgaca cctaatccaa cctccattat taccacaagg ataacgagtg acccagtgtt
    34801 ctttagcttt tggtgtcaaa gatattaaca ttttttctac tgctggaact tgcttgtcac
    34861 ctatttgaat cataacagtg aatgcacctt tttcaaaaaa agcataaaat aaatgaaaag
    34921 atttatggct atatttgtaa ccccaaccat aattatttcc aaaaggaaat cgaagttctc
    34981 ttgataaatt atattgagtc tccaagtaag tttccaactt acacaagcgt gcatatccat
    35041 ttttacctat atattctatt atttgagaca agcaaggttt attgctttta tcaagcatac
    35101 gctcatacat tagaatttac ctccgttttt acttttaagt atagcaaagt aattatgaca
    35161 acagtatgtc aagtttttat gtctgattat actaatattt aaaaatataa agtaattagt
    35221 tttagctaat ataaaaatat gatatttata tatgttggaa aaaaatgtaa aataatgata
    35281 aaatatagtt tataatacaa aagtataatt atattataat tatatgtatt tagttggatt
    35341 tgtgtattta aaaatgtata atttatgctg attactgcta aaaaagcata ataatattgc
    35401 attgtaagat tttataaact tctaattgaa aggggataat tcaaatggat aagagatatt
    35461 tagaatccga tgtatttgaa gcttttcaag aaagactttc ttatcttttc aatgaatttg
    35521 attatatcta tgtatctttt agtggaggaa aagatagtgg tttactgcta aatttagttt
    35581 tggattataa gagaaagaat aatataagtt ccaaaatagg agtatttcat caagattttg
    35641 aagctcaata cagtttgact actgaatatg ttgaaaaagt atttgaagag aacattgaag
    35701 atattgaacc atattgggtg tgtttaccaa tggctacaag aactgctgtg ggaagttatg
    35761 aaatgtattg gtatccatgg gatgatgaga aagaggaatt atgggtaaga gaaatgccag
    35821 tcaaagaata cataataaat caaaaaaata atccttttac ttattataaa tataaaatga
    35881 ggcaagaaag tttggcaaaa caatttggta gatggattag agatatacat gaaggtgcaa
    35941 aagttgtttg cttattagga acaagagcat cagaatctct acaacgttat tgttctattg
    36001 tgaataaaca gtatggatat aaaggaaagt gttggataac taaggaattt aaaaatgtct
    36061 ggacagcatc tcctatatat gattgggaaa tagaagatat atggttggcc cactataagt
    36121 ttgattatga ctataataaa atttatgact tattctataa agctggaata gctccaagaa
    36181 aaatgagagt ggcatcacct tttaatgatt cagctaaaga gagtttaaat ttatacagaa
    36241 tattggaccc agatgtatgg gtgaagttgg ttgctagagt acaaggagtt aattttacct
    36301 ctatttatgg aaaaacaaag gctatgggat atcgtagtgt taggttacca tatggacata
    36361 cgtggaaaag ttttacatat tttttgcttg ataccttacc tgaaaatata agaaataact
    36421 atattaaaaa attttcaaca tctattgagt tttggcagaa tacaggtggt ggtttgtcag
    36481 aaatagttat ccgtgaattg ttgagaaaag gttataaaat agaattaaat ggagtttcaa
    36541 atcatacaaa agataaaaag agtagagtta tatttttgga tgatatacct gatgatacag
    36601 atgatatcaa atttactaag gatataccaa gctggaaaag aatgtgttat tgtattttaa
    36661 aaaatgacca tatgtgtagg tttatgggct ttggtcctac aaaagaacag agaattagaa
    36721 cagaatatat taagaagaaa tatgaaaaaa ttcattagat aggagttaag atgctatgga
    36781 atataaaagt cctgtatatg gaatcatcgc agtgccaatc gaaaagatag aatctaacga
    36841 ctataatcca aatgcagtag ccccaccaga aatgcagttg ttgtacaaaa gtataaaaga
    36901 agatgggtat acaatgccaa ttgtctgtta ttataatgag gaaaaagata agtatattat
    36961 tgtagatggt tttcatcgct atagaataat gcttgaaaat gaggatatat atgatagaga
    37021 aaacggactt cttcctgttt cagtaattga taaatctctt gatgaaagaa tggcaagtac
    37081 tattcgacac aatcgtgcaa gaggctctca taatgtggat ttaatgagta aaattataac
    37141 tgaactttgt gaaattggaa aatctgatga atggatatca aagcacctgg gtatggaaat
    37201 tgatgaaatt cttagattga agcaaataac tggattagct tatttattta aagataaaga
    37261 gtttggtaat gcatggattc cttttggctc tgatgtagaa gaagaaaact aaagatattt
    37321 attaaaagaa aaagatatat taaaaaagaa aacctaaaat atatattaaa aaataaagag
    37381 ttttaatatt atataa
//
LOCUS       DAMKOJ010000038        37264 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000038 DAMKOJ010000000
VERSION     DAMKOJ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37264
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.040"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            170..880
                     /locus_tag="PC592_001979"
     CDS             170..880
                     /locus_tag="PC592_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055952.1"
                     /translation="MIKIAICEDEKEQQELLKRYINQIFDALSVKCRLEVFNSGEELL
                     EGYSKDTDVLLLDIQMGQINGIDTARKVRVLDDKVEIIFITALIEYALEGYEVRAYRY
                     LIKPVKYNNLKDNIINCIKEVDIKNKYIMVKAQGSQTKLNVNEITYIEVQKETITIHT
                     LNEVYKINGTMSNIEKEIDCSRFFRCHKSFLVNLEHVKSIKQYVAILENSKEVPVSRY
                     RFKETKDKFFDLIEEKLC"
     gene            874..2211
                     /locus_tag="PC592_001980"
     CDS             874..2211
                     /locus_tag="PC592_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4055953.1"
                     /translation="MLDSVYSLAIINMVIFIALFFMLMNKIGYTYRCKTNIQLILILI
                     LSAILIINGMPFGIVPLHALIRIILILSLICKITYQINIKKATINSVIYSLLYILIGC
                     SMYWILQFSWKYVGHYILKANTVINFIIIFIGVYFFDILQKIYNNKKYYLYIILTIAV
                     NVVIVLFVNISTEKMDDLYTIVTKNHIEYSYNVYTMYFSLFMKNTFPYILFIVNVLLI
                     SIFINSIKSEKEKIKAEFVSEKLDMQYKYYFMVKESQEKMRQVYHDMNNHMKNIKSLK
                     NSSEDVNKYINSIEDEVKNTKNIYNTGNVLLDIILYEKSRLCMENNIDFNVGIDFSKC
                     EFIEMIDVSSIFSNLIDNAIEACSNIDDNNIEKYITIKSTFIKGYYIIRCENSKMNKV
                     IIKNNKIFTSKKDKFLHGIGIESIKSSIRKYNGELKIKDSEYKFIVTAHIPIE"
     gene            2388..4955
                     /locus_tag="PC592_001981"
     CDS             2388..4955
                     /locus_tag="PC592_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055954.1"
                     /translation="MTTFKLAVSYMKRQKGKTVALLSCIVLAVMLIFSMIVIRDSGYD
                     SQIKEAKDLHGDYHIWFEGLEKDKTQDLTNEEGISKSNTSKELCEVVDKESGVKLYLN
                     SFDKGFLSSLGYKIEGREPIKDGEIVIEKEATRQMGISNPLNKNIDLMLLNKYIDDNE
                     INHMDSANKTFKVVGVIEKLDKYYDKSRYSITLRAFVYKDSNLPIKIKDTYNGTIYLK
                     SEKNIPQFITKMTKKIDTNVFNLHENGEVDLAKNQRQNSKFSKENIINSVLLVSVSTI
                     VIYNIFNIIFQDMTSQIGIMKSIGMSNKKVRNMLIIMSFIYIILGTLVGIVFGMIFSY
                     VGLRVVYGYSSMLTIQISSVICSFAVSIISVFISSFIVIKKFRKMSIIEAIRSSDKYE
                     KKSKNDNKKIDGKSKNLLISMATRNLWRNKPRTILTILAITLVGIMFILNLGAKSLLK
                     KNMEEGITGGSWSMSYGSVDKTVEGDSRSSESLFYKLDNNLIQKVNGMKGVRHVEPHF
                     YNHRGHILLSKNKLSKAYKDELDRKNSSYQEEHNNEYPLLIRGYSDDMLKQRQEFIEK
                     GENILSTTSGKYKKVILVNNTNSQVTHSFDAKIIDDVKIGDIIEIKLPVYRDGIEKYE
                     NFKVEVGAIMKELYASSQDGNTQAQGAQMIFKENDYKELTGQKEYNKLFVIVEKGQLY
                     SVERRLEETTKNYGSTEINGKGEELKLIGMQQSSEERLSVIYQFLTILILAVNIIFIM
                     RSNIITRRKELATLRAIGMSIKSIKKILIIESQMYGMVASIIGAIIATVYHNYGLAKT
                     NKVLLEGGYTRIIEPNIPFSQIIILFTIFIAMGFISIYVSKDKIEGTTITEGISQNN"
     gene            5014..5697
                     /locus_tag="PC592_001982"
     CDS             5014..5697
                     /locus_tag="PC592_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055955.1"
                     /translation="MENRIMKKLAIKNIKKVYGKGDNKVYALNGIDLEIQPNKFTTIV
                     GQSGSGKSTLLHCMAGLDKPTDGKVFIDDLDLYTLNDDKLSKIRREEFGFIFQSYNLI
                     PVINVYDNIVLPISISKRKIDKDYIIDLIAKLGIKSQIDKFPNELSGGQQQRVAIARA
                     LANKPSIIFADEPTGNLDSKTTNEVVKLLKLCVYEYKQTLVMITHNAEIANNSDNIIN
                     ISDGKIVLI"
     gene            5960..6820
                     /locus_tag="PC592_001983"
     CDS             5960..6820
                     /locus_tag="PC592_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4055956.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKVLNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMYALKLIGDSKEINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVEIDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            6810..8681
                     /locus_tag="PC592_001984"
     CDS             6810..8681
                     /locus_tag="PC592_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4055957.1"
                     /translation="MKYKDLNENIIKLTGGKENIKSVAHCVTRLRLTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSVKGERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILHSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWSMGIIIGGLKKILPKALHYFLVPVLSLIITLSVTLTIFGPIGMWIGDVLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPIALNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGL
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEMSNFTFMIIAVLVSFVGATVASYLLGIP
                     SDEKEEAKNANEKELELVVNEDNSRTISVGSVAKGQVISLEEVNDKAFSSGALGKGVG
                     VIPSESKSTVMSPVDGTITIVFQTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFDSDKIIEAGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            8701..10143
                     /locus_tag="PC592_001985"
     CDS             8701..10143
                     /locus_tag="PC592_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF4055958.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYECLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     KKFDGKVRHWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNINIEVTDEDKKAFEEGRLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPVGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDNY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKFNGENLNLLDV"
     gene            complement(10422..10955)
                     /locus_tag="PC592_001986"
     CDS             complement(10422..10955)
                     /locus_tag="PC592_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF4055959.1"
                     /translation="MNMKKEALEVLKNRRSIRKFKSNQVSKEELDLVLEAGTYAPTSK
                     GSQEPIIIAVQDEDTVSQLDALNARILNIEKTPHPYYGAPTILLILAPEDALIPVENC
                     SLVAGNLMNAAYAVGLGSCWIHRAKEMFESIEGKELLKKWGLPETLKGVASIALGYPD
                     CPHPKAASRKEGYILRV"
     gene            11093..11530
                     /locus_tag="PC592_001987"
     CDS             11093..11530
                     /locus_tag="PC592_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF4055960.1"
                     /translation="MRMSTQFTVSVQMLLLIMVLDDRKVTSEMISKSTGGNPVMVRQL
                     FGKLKEAGILNVSAGRGATVLAKKPSEISLWDIYMAVEEYSSSELFKFHPKISEGCNI
                     GRFFKEILGNHLDEAIHAMADKMSKVSLAQLLEEWESVNKESK"
     gene            12718..13926
                     /locus_tag="PC592_001988"
     CDS             12718..13926
                     /locus_tag="PC592_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055961.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLI
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALIGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPNMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTSIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            13957..15336
                     /locus_tag="PC592_001989"
     CDS             13957..15336
                     /locus_tag="PC592_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4055962.1"
                     /translation="MIGSISINEIDKKRFKLDDLSRKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEIGVGGLATAIKASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGIKREMIENNLGGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYIRALSREAVESTYERLVKVAKG
                     ATMMTETEVEVEFLGGCYNTLNNHTLANLVSECMNEIKQEPWTQEELDFAAELDRQSP
                     QQYKDMISKYNLQEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYAAKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(15713..17041)
                     /locus_tag="PC592_001990"
     CDS             complement(15713..17041)
                     /locus_tag="PC592_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055963.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDSFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQDAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTTCYIKESIENSINIKVCIGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(17651..18865)
                     /locus_tag="PC592_001991"
     CDS             complement(17651..18865)
                     /locus_tag="PC592_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF4055964.1"
                     /translation="MRNCIIAQSGGPTAVINASAIGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYRINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFILETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASGTDLKQAADVGAYGIELSKKEYTGVMAII
                     NRTCNNPYKYEVGHTDISKIANKTKYFPKEWINEECNYITDEALDYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            19273..19989
                     /locus_tag="PC592_001992"
     CDS             19273..19989
                     /locus_tag="PC592_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HDF4055965.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTVGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIA
                     AGVKNCRKAIDEAATKFGLE"
     gene            20124..20750
                     /locus_tag="PC592_001993"
     CDS             20124..20750
                     /locus_tag="PC592_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF4055966.1"
                     /translation="MKKEMIKDYLLITVSAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPFFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINSTCTQ"
     gene            complement(20934..22478)
                     /locus_tag="PC592_001994"
     CDS             complement(20934..22478)
                     /locus_tag="PC592_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4055967.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEKLNVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLQTLQVEK
                     SNLSDEYYINFLIHIAICIRRISIKRYINLSEGFFRELLEHEYFEKSKILCSNLGEAF
                     DVEFISEEVCYILLHVEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGNILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(22504..23145)
                     /locus_tag="PC592_001995"
     CDS             complement(22504..23145)
                     /locus_tag="PC592_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDF4055968.1"
                     /translation="MKYLIDSANLDEIQKCLKCGFKGITANPSMYLKENINFYEFIET
                     CTNLNPEILTAEVIGNNLYELINSCDKILNINKDTIIKINFSEIGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICDLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTVDGANTFERDWSKVNK"
     gene            23416..24567
                     /locus_tag="PC592_001996"
     CDS             23416..24567
                     /locus_tag="PC592_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF4055969.1"
                     /translation="MINFYQPSRINFGQGTISELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLDLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNVDKFAKVARMLNQELEKVEDNEAAKTLGKEIER
                     FLKNVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            24580..25392
                     /locus_tag="PC592_001997"
     CDS             24580..25392
                     /locus_tag="PC592_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF4055970.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAIKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGQEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVESLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIEFAGLGIAMGNATDEVKSIADFVTDTNVNDGVAKALRKVLS"
     gene            25418..25909
                     /locus_tag="PC592_001998"
     CDS             25418..25909
                     /locus_tag="PC592_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4055971.1"
                     /translation="MFNIFKKKENKVEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVSVFDTKHAITIKSNDNTNMLIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            26405..27106
                     /locus_tag="PC592_001999"
     CDS             26405..27106
                     /locus_tag="PC592_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4055972.1"
                     /translation="MINIAICEDNFVDRGILNDYLIRIMNENSYNISLFKSGEELLDN
                     YPDDLDILLLDILMKKINGIDTAKKIREFDSNVEIIFITSLLEYALQGYEVKAFRYIL
                     KPIEYEQLSINIIQCLDDINNKASKFVYIKCNSDIVKIDIESILYIEKISRYIFVYTE
                     DQVYKSKMNLKDIEKKLQHYKFYRCHLGYLVNVNKIDCLGSSEVSIYNHSIPVSRGKR
                     KILKEFIIDSKEKSL"
     gene            27487..28401
                     /locus_tag="PC592_002000"
     CDS             27487..28401
                     /locus_tag="PC592_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4055973.1"
                     /translation="MLLAYIFLIFLVFIIKFVVTKNNFIKNIHLIFFTFINIVSFLLI
                     FRGAAKDINVNFVDNIFIIIIGFTIVIFNLYLLSMMDKLLESRRIEIENKFMKEKIEI
                     EYKYIKKLQYSNENIRILKHDIKNHLICIRNIHNNKEAFDKYLDSVDIEVNKINDIYD
                     TGSIIVDAILDEKKIICDNYNIKLYVKANFTGCDFISAFDLCTIMSNLLDNAIESNLK
                     VKNSDCRNITVKANCEKYMLIIIVENNKSNKIIKSKQSIITDKKNKTIHGLGLKSVKK
                     SISKYNGDLFVEYNDENFKVKIIIPTNI"
     gene            28495..28668
                     /locus_tag="PC592_002001"
     CDS             28495..28668
                     /locus_tag="PC592_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055974.1"
                     /translation="MIKIKKITDKEKVVVSAQAKKPCSCAGQVLKYPPVSNSCLYDYD
                     DYNQPRWYEAQCQ"
     gene            28741..30000
                     /locus_tag="PC592_002002"
     CDS             28741..30000
                     /locus_tag="PC592_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="HDF4055975.1"
                     /translation="MNYKFDDSVKLLKNGEYVILGNTKNGQWIKMTNYIYNIFKIGID
                     NSLDINELKKCLEDDEDRQFIQNLYENLLDMRIIYDEINNVAFQNKIASLEITNRCNL
                     KCVHCCVDADNLISEKEELSTIELKDAIKKIVEWNPMNIMLSGGEPMVRSDFFEILTY
                     LKSIYKGNIIVSTNATLINKNNVELLIKNVNKLEISLDGVNEQTCSIVRGKGVFKKVI
                     DSVNLIKSFGFDNITLSMAVGNKNEYLEEEFKDLCKNLGVGHMIRRFGPVGRGKENEH
                     LFLDNNKDEAYIPENFLKDNYDGNMGVTSCKAGIYEIFIRHNGDIYPCPSFMSDEYKI
                     TNLCDIQQISEIKDKYINKVDVFSILEKINPEIYKNCIDCNVNLFCWTCPGEIEELKD
                     SKASLFNKCSKIKNILYKRVWGNDGVC"
     gene            29994..31010
                     /locus_tag="PC592_002003"
     CDS             29994..31010
                     /locus_tag="PC592_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="HDF4055976.1"
                     /translation="MLATFWITNECNMKCRYCYEGNNKNNKVMSKTLIDKSISYVLNQ
                     SNSLDDDELVIQIHGGEPFLEFNLIKYIISEFKSEKFNKNIIFSTTTNGMLLNNDILD
                     FIQLYIAELTISIDGAKNTHDKNRQSINGKGTHDIVIENSRKILKIKPNVRVRMTFDT
                     ETVGNLSNDIKYLISEGFRTIVPVPDMFETRWNNNHIEVLKNQIYQIKEIIGNSKDIL
                     VSLTDTNIYKYKGVCSGGKLSFNICPDGYIYPCTLAVGNKDFSIGNIYDGIDKTSRDK
                     FLSKSYLDNNDCKGCDLSNSCDGNRCKIINKLTRGSYFLPSPINCAIQNIKHEINISK
                     EIVL"
     gene            31000..32091
                     /locus_tag="PC592_002004"
     CDS             31000..32091
                     /locus_tag="PC592_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF4055977.1"
                     /translation="MYYSFVELRRNSLKRIKVALIDSGIDINHKYLKNNILYGKSYIY
                     KDNKIVVSNEIEDINGHGTSCASIIKSEYEYVDFIIIKIFDRDGLTNIKVLEESLNYL
                     ISIDVKIINLSLAIHGDINSCKDLYKICEKLKNQNKIIVSSLANYNYIEESYPSIFDN
                     VIGVKGNLLKKRSSFWYNSEYKYQCVVDDSDRIVADLGNSFKLVEKSNSFSAAKMSGK
                     IAKIIANKVDISFDGLSRILEELSECTNWKDEDLYTNKRRIDYKQYLYENNNINLNRV
                     LKVLVDNLNIGCNVDILFDSILFSKYIGLKNNNCIEILKKLENEFNIKIDYTKVYKED
                     LISIYTLTNLIEKESICEHFRNCKYLQKL"
     gene            32051..32716
                     /locus_tag="PC592_002005"
     CDS             32051..32716
                     /locus_tag="PC592_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055978.1"
                     /translation="MNILETVNISKSYSIGDKKSYILKDINIKIKEGEFISIIGPSGS
                     GKSTLLHILGGLENPTTGIVKIIGKSIYDLSEIKLAEYRRRRFGFIFQQFNLIPVLNV
                     RENIEMPLMLDRAKIDNRFIKEIIEFLGLEEKENYYPNQLSGGQQQRVAIARALVSKP
                     DIIFADEPTGNLDTKNSDEVIKLLMKSIHKYNQTVLLITHDYKIAKNTDRTIKILDGK
                     LEL"
     gene            32717..34492
                     /locus_tag="PC592_002006"
     CDS             32717..34492
                     /locus_tag="PC592_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4055979.1"
                     /translation="MIQCQEGNKLKNTINMKKFLYLIIQGNKKLVIISFLMMIVVAMI
                     DLYIPQIIRNILDIAIKSKNITMLIKLILQFILINIILSNLELFLEYNYSKMKKKITT
                     KLKLKLLRHLSKLDGRFFSEIKTGNIMNIVEYDVMMLDRFGIELIFSLIVDIITAFIS
                     LYFLIKIQSKLLVIVVVIQIVISFTQYIFTKMISKYTQNIRSNAGSISNIVQEYISNI
                     MNVVIHKGELNFFTQFLSMQKNFVSKCIKLDMIMAGNVSLSKILNSLIVISIYGYGGY
                     KIINGEITFGELVAFQQYTGMLIGPCMNIIKSNAIVQQSLVSINRIFDLLNEEVNMKQ
                     ENTGEIFQSGITKKIRMDMIDVSFSYDKEDVLHNINMSLESGNIYGIVGGSGSGKSTL
                     IKLIYRLWDIESGSIRINDVDIRDYNLKNLRKNITIITQEPLLLNDTVFNNIILSNKN
                     INYELVVRICKELDIYDFIVSLPNEFNTIVGENGVKLSGGQKQRISIARAMLSNSSIL
                     VLDEATSALDNISQKDLLKSMKKFLNNKIVIIIAHRLSTIKDSDKIFVINNGEIIESG
                     SHKDLVSQNGYYCNLLEDKKEYSYC"
     gene            34662..37193
                     /locus_tag="PC592_002007"
     CDS             34662..37193
                     /locus_tag="PC592_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4055980.1"
                     /translation="MRLSLAYVKKYFGRSISIALSIIISISLIITVGILTKNTQKASV
                     DRIKYESGDYHVKVKNISGNVISDYKKQFDISMMGVSSYYDSSEFNGKLMLNLIKSNE
                     DYIKIYNSKILNGRFPTSDNEVALEEWVMLNLGLKLDINQNIKIKLYNSKETKNYKVV
                     GILKDRPYYKSIGMAELILPFTENIIKETNLEAQIRFKKDIYRNLSKLMNDNHISRKN
                     VSENRILLDALGESNGLNYDFIFTCIISMIVSGVVIYSIFRISIIQRISEYGIIRALG
                     ANIFNVFNIIFVELFAISLVSIPIGVLIGIISSKYITLFMGNLLIGNIVKINNVEINL
                     DVVMISIITVLVNILIISFLTCTNVNKISPIKCIKKDISKKNSRESSILNTRRLLNLL
                     PIEYIISLKNILKNKKNFVIIVLSMSGGCIIFILTNFTNILDERQLEYTSKVATENSD
                     YNISFAPVTPLNIGISEENLKQIRQLEGIENVKTSQVMYSRMILNKDNINNMNYFEKV
                     NKSAYNKKALNGLLVKKDNEYILKSNLYGYDNSSIDAQKSFVISGDIDLDKMNNGNVA
                     ILYMPDPSLFTNIKDSRPVLNLKVGDIVKLRFRSDYVSDENFAKLKDKGEYVEEEFKI
                     GAIVSNILNVDGYYAGMDSASIIISQNQFKNIVGIHSYRMLDIKKIPTVDNIELGKNI
                     IDISSKIQGSIVRDFTQEIKNIKIIEDNKKILIYTIILVLFTISFINIINNINYNLYS
                     RINEFGVIRAIGLDNNSFRKMLLFEGVVYGLISASVSITFGILGQSILYNILKGNLMN
                     AKFIIDYKSYILVIILTIILGVVATYLPSKKVKKLSIIESINIIE"
BASE COUNT        14748 a         3812 c         6028 g        12676 t
ORIGIN      
        1 taaaagagta tactgcataa aaaataataa tcacttatga gtattccata ataactcata
       61 aatgattatt atttaagaat aaagtacgta actgaataag aagattaaga aaagttttag
      121 ctttgttaag aataatttaa gtatataaat gtgtatgggg tggaattagt tgataaaaat
      181 agcaatatgt gaagatgaaa aagaacaaca agagttgttg aaaagatata taaatcaaat
      241 atttgatgca ttgtctgtta aatgtagatt ggaagtattt aattcagggg aagaattact
      301 tgaaggatat tcaaaagata ctgatgtact tttattagat atacaaatgg gacaaattaa
      361 tggaatcgat actgcgagaa aagttagggt actggatgac aaagtagaaa ttatatttat
      421 tacagcatta atagaatatg cactagaagg ttatgaggta agggcttata gatacttaat
      481 aaaaccagta aagtataata atttaaaaga taatataata aattgtataa aagaagtgga
      541 tataaaaaat aaatatatta tggtaaaagc acaagggagt caaactaaat taaatgtaaa
      601 tgaaataaca tatatagaag tgcaaaaaga aactataact atacacactt taaatgaagt
      661 ttataaaata aatggcacaa tgagtaatat tgaaaaggaa atagattgta gtagattttt
      721 tagatgtcat aagagttttt tggttaattt agagcatgtg aaaagtataa aacagtatgt
      781 tgctatactt gaaaacagca aggaagtacc tgttagtagg tataggttta aggagacaaa
      841 agataaattt tttgatttaa tagaggagaa attatgttag atagtgtgta tagcttagct
      901 attataaata tggtaatatt tatagcttta ttttttatgt tgatgaataa aattggttat
      961 acttacagat gcaaaactaa tattcaactt atattaattt taatattatc tgcaatctta
     1021 attataaatg gtatgccttt tgggattgtg ccattacatg ctttaataag aataatttta
     1081 atattatctt taatttgtaa aattacttat cagattaaca taaaaaaagc tactattaat
     1141 tctgttatat atagcttgtt atatattttg atagggtgta gtatgtattg gattttacag
     1201 ttctcatgga agtatgtagg tcattacata cttaaagcaa atactgtaat aaattttatt
     1261 attattttta taggtgttta tttttttgat atactacaga aaatttataa taataagaag
     1321 tattatttat atataatttt aacaatagca gttaatgtag ttatagtttt atttgtaaat
     1381 atatcaactg aaaaaatgga tgatttatat acaatagtaa caaagaatca tattgaatat
     1441 agttataatg tatatacaat gtatttttca ctttttatga aaaatacatt tccatatatt
     1501 ttatttatag taaatgtatt attgatatct atatttataa attctataaa atcagaaaaa
     1561 gaaaaaatta aagcagaatt tgtaagtgaa aagttagata tgcagtataa atactatttt
     1621 atggtaaaag aatcacaaga aaaaatgaga caagtatacc atgatatgaa caatcatatg
     1681 aaaaatataa aatcgctaaa aaacagtagt gaggacgtaa acaaatatat taatagtata
     1741 gaagacgaag taaaaaatac taaaaatatt tataatacag gaaatgtact attagatatt
     1801 atcttgtatg aaaaaagtag attatgcatg gagaataata tagattttaa tgtaggcata
     1861 gattttagta aatgtgaatt tatagaaatg attgatgtaa gtagtatatt ttcaaattta
     1921 atagataatg caatagaagc atgtagtaat attgatgaca ataatataga aaaatatata
     1981 actataaaaa gtacctttat aaaagggtat tatataatca gatgtgaaaa cagtaaaatg
     2041 aataaagtaa taattaaaaa taataagatt tttacttcta aaaaagataa attccttcat
     2101 ggcataggta ttgagagtat aaaatcttca ataagaaaat acaacggaga attaaaaatt
     2161 aaggatagtg agtataaatt tatagttact gcccatatac caattgaata aaaattcaat
     2221 agattgatgc atttaaaaag cttataagct agtctttaat atgctagttg acggtgaaaa
     2281 aataccactt gtcggactta tattgaataa aaattttaaa aatgttacct ttacaaaaaa
     2341 ggtagcattt tttatacaag gatttaatag aagaaggagg taaagttttg actacattta
     2401 aactagcagt ttcttatatg aaaagacaaa aaggaaaaac agtagcacta ctatcgtgta
     2461 tagttcttgc tgtaatgctt attttttcta tgattgtgat tagggattct ggatatgatt
     2521 cccaaataaa agaggcaaag gatttacatg gtgattatca tatatggttt gagggactcg
     2581 aaaaggataa aacacaagac ctcacaaatg aagaaggtat atcaaagtca aacacttcaa
     2641 aagagctatg tgaagttgta gataaagaaa gtggtgttaa gctttattta aattcatttg
     2701 acaagggttt tctaagttct ttgggatata aaatagaggg aagagaacct ataaaagatg
     2761 gagaaatagt aatagaaaaa gaagctacaa ggcaaatggg gatatctaac ccattaaaca
     2821 aaaatataga tttgatgctt ttaaataagt atattgatga caatgagatt aaccatatgg
     2881 atagtgcaaa taaaacattc aaagttgttg gtgtgataga aaaattagat aaatattacg
     2941 ataaatctag gtatagtatt acacttcgag cttttgtgta taaagactcc aatttgccaa
     3001 taaaaataaa agatacgtat aatggaacaa tttatcttaa atcagagaaa aatatacctc
     3061 aatttataac taagatgaca aaaaagatag ataccaatgt ctttaatctg catgaaaatg
     3121 gtgaggttga cttagcaaag aatcaaagac aaaattcaaa attcagcaaa gaaaatatta
     3181 taaattcagt gcttttagtc agtgtatcaa ctattgtaat atacaatatt tttaatatta
     3241 tttttcagga tatgactagt caaataggta ttatgaaatc tattggtatg tcaaataaga
     3301 aagtaagaaa tatgcttatt attatgagct ttatctatat aattttagga actctagtag
     3361 gaatagtatt tggaatgatt ttttcatatg ttggtttaag agtagtgtat ggatacagct
     3421 ctatgctaac aatacaaata tctagtgtaa tatgttcttt tgcagtttca atcatatcag
     3481 tatttatttc tagctttata gtaattaaaa aattcaggaa aatgtctata attgaggcta
     3541 taaggtcaag tgataagtat gaaaaaaaat caaaaaatga caataaaaag atagatggaa
     3601 aaagtaaaaa tttacttata agtatggcaa ctagaaatct atggagaaat aaacctagaa
     3661 caatattaac aatattagca attacattgg ttggaataat gtttatctta aatctaggtg
     3721 ctaaaagttt gctaaaaaag aatatggaag aggggataac aggtggttca tggtcaatgt
     3781 catatggaag tgttgataaa actgttgagg gagattctag aagttcagaa tctttatttt
     3841 ataaattaga caataattta atacaaaaag tgaacggcat gaaaggtgta aggcatgtag
     3901 aaccacattt ttataatcat cgtggccata ttttactttc taaaaataag ttatcaaaag
     3961 cttataaaga tgaattagac agaaaaaatt cctcttatca agaggaacat aacaatgaat
     4021 atccactttt gataagaggg tatagtgatg atatgttaaa gcaaagacaa gaatttattg
     4081 aaaaagggga aaatatacta agtactacat ctggcaagta caagaaagtc atcttagtta
     4141 acaatacgaa ttcacaagtt acacattctt ttgatgcaaa gataattgat gatgtgaaaa
     4201 taggagatat tatagagata aagctacctg tatatagaga tggtattgaa aaatatgaaa
     4261 actttaaggt agaggttggt gctatcatga aagaattata tgcatcaagt caggatggga
     4321 atacacaagc tcaaggggct caaatgatat ttaaagaaaa tgactataaa gaattaacag
     4381 gtcaaaaaga gtataataag ctttttgtca tagttgaaaa gggacaatta tattctgtag
     4441 aaagaagatt agaagaaacc actaagaatt atggatctac tgaaatcaat ggaaaaggag
     4501 aagaactaaa acttattgga atgcaacaaa gttcagaaga aagactttct gtaatatatc
     4561 agtttttgac tatattaata cttgcggtga atattatttt tattatgaga agtaatatta
     4621 ttacaagaag aaaagagctg gcaaccttaa gggcaattgg aatgagtata aaaagtatta
     4681 aaaagatact aattattgaa agtcaaatgt atggaatggt agcttctata ataggagcta
     4741 taattgcaac agtatatcat aattatggtt tggctaaaac gaacaaagtt cttttggaag
     4801 gtggatatac taggataata gaacccaata ttcctttttc tcaaataatt atactattta
     4861 caatttttat tgctatggga tttatttcta tatatgtatc aaaagataag atagaaggta
     4921 caacaataac agaaggaatt tcacaaaata attaaggcta tggaatgaca agataaaaat
     4981 gtaatactat ttagtgggat ttaaataaga agaatggaga accgtattat gaaaaaatta
     5041 gctataaaga atataaagaa agtatatgga aaaggggata ataaagtata tgcattaaat
     5101 gggatagatt tagaaataca acctaataaa tttacaacta tagttgggca aagtggctca
     5161 ggcaaaagta cattacttca ctgtatggca ggtcttgata aacctacaga tggaaaagta
     5221 tttatagatg atttagattt atatacccta aatgatgata agttatcaaa gataaggaga
     5281 gaagagtttg gatttatatt tcaaagttac aatctaattc cagttataaa tgtttatgat
     5341 aatatagtac ttcccatttc aattagtaaa agaaaaatag ataaagacta tataatagat
     5401 ttaatagcta aactaggtat aaaatctcaa attgataaat ttcctaatga attatctgga
     5461 ggtcaacaac aaagggtagc aattgctaga gcacttgcaa ataaaccttc aataatattt
     5521 gcggatgagc ctacaggaaa cttagatagt aagacaacta atgaagttgt gaaacttcta
     5581 aaactctgtg tatatgagta taaacagaca ttagttatga taactcacaa tgctgaaata
     5641 gctaataatt cagataatat tataaatatt agtgatggta aaatagtatt aatttagtat
     5701 ataaactttg caagataatc gcctacagag tctgtagtta tataattaaa aaaatattta
     5761 ggaaaccgtt gacagattta catagatagt ataacatata ggatataaaa ttaaacgaaa
     5821 aagaatttta attatggcga cgtagtcata attttgagta tgttactgat tagcaggcag
     5881 aactcaagta tatatgtgaa aaatagaggg atactctata catatatgct tgagttcttt
     5941 ttattgaagg gaggaatata tgaaaataat tcagatttta aataataatg tggccttggt
     6001 aaaaagaggc aaaaatgaaa ttattgtatt tgttaaagga attggcttta aaaaaagagt
     6061 aggacaagta ataaatgaaa atgaaataga gagaacatat atattagatt catacgatat
     6121 gttagaacac tttagttatc tattacaaaa ctcagactcc aataatatag ttctcattaa
     6181 tgaaataatt gaatatggtg agaaagtttt aaatataaag tcaagtgatt atctaagttt
     6241 aaccttacta gaccatttag agtttttact taaaagatgt gaaaagaatc aatttataaa
     6301 aagtcctttg gtatggaatg ttaaaagatt ttatcccaaa cattttgaaa ttggaatgta
     6361 tgcactgaaa ttaattggtg atagcaagga aattaatctt cctgatgatg aggcagtatc
     6421 aatagcactt cattttgtaa atatggaggt aaacaaagag tctcatgata gtacgattgt
     6481 agagttaaga actttagcag atatagtttc tataataaaa tatcatttta atgtagagat
     6541 agatgaaact tcaacaaatt atatgagatt tactactcat ctacagtact ttatccaaag
     6601 aattatgtca gatgaagctt caatagatga agataattct atagatttat ataaacaagt
     6661 aagtcaactt tacccaaagt catttggaag tgttcaaaag ataagaaaat atataaaatc
     6721 acaatttaat gtagatatat ctataagtga agaaacttat ttaatgttgc atataaatag
     6781 ggtgactcaa agactggagg caaaatcaga tgaaatataa agatttaaat gaaaatataa
     6841 taaaacttac agggggaaaa gaaaatataa agtcggtagc acattgtgtt actcgtttaa
     6901 gacttacttt aaatgatagg agtatcgctc aaacagaaga aattaaaaaa ttaaaaggag
     6961 taattgatgt agtttctaat gatgttgctt atcaaattat aataggtact catgttgtag
     7021 atgtatataa cgagtttatg tctatgatag gtttaagttc aagtgaatca agtgtaaaag
     7081 gtgaaagaaa aaagggaatt agaggtatca aaggtatatt taattccatc tttgtggtag
     7141 tctcagaaac tatgacttca gtaattgaag tactacttgc agctggtata cttgcaagta
     7201 tattagcgct tttaaatatg tctggtatac ttcatagtga tagtcctaca tatcaaatat
     7261 tagatacatt aagaagcgct acatttcact tcttaccagt attaattgca atagcatcag
     7321 caaaaagact taatgtaaat ccctatatag cagtagtgtt agcagttaca ttactatctt
     7381 catcaataga tggtgtagaa ggattaagtt tatttggtat aaatttacag gctacaacct
     7441 atgcaaacag ctttattcca atacttttag gagtatggtc aatgggaatt ataattggag
     7501 gtttgaaaaa aatactacct aaagcactac actatttttt agttccagta ttatctttaa
     7561 taataacttt atcagttaca ttaactatat ttggacctat tggtatgtgg attggtgatg
     7621 tattaaacta tgcatgtatg tttttaattg atacattagg aaattggagt gttgttgcat
     7681 tatatgcagc tttacaacca ctcttaatag tctttggcgc agcaaatttt actatgccaa
     7741 tagctttaaa ttctgtgaca acattagggt atgacccaat ttttatggga gcagcaacaa
     7801 tatctgatat tgcagtttgt ggtgcaatgt ttggatattt cttaaaaact aggaataaag
     7861 agcaaaagca attatttggg acagtgagtt ttagtgcact tatgggagtc acagaacctt
     7921 cagtgtttgg tgtgtttatg aaatatagaa gaccatttgt agcagtaatg ataggcggag
     7981 gcttaggtgg cctaatagca ggattagcac aagttaaaac atatggaatg gtttggggat
     8041 tagctgcatt accaacatat cttgttggtg gagagatgtc taactttaca tttatgataa
     8101 tagctgtatt agtatcattt gttggagcaa cagtggcttc ttatttacta ggaatacctt
     8161 cagatgaaaa agaagaggct aagaatgcta atgaaaaaga attagaatta gtagttaacg
     8221 aagataattc aaggactatt agtgttggaa gtgttgcaaa aggtcaggta atttcacttg
     8281 aggaagttaa tgataaggca ttttcatctg gggcattagg taaaggggtt ggagttatac
     8341 ctagtgaatc aaaatcaact gttatgtctc ctgtagatgg aactataact atagtatttc
     8401 agaccaaaca tgcctatggt atagtgactg atgaaggatt agaaatatta attcatattg
     8461 ggatagatac tgtaaacttg gatggaaagt tctttgaaag tcttgtaaca caaaatcaaa
     8521 gggttaaaaa aggagatgct ttagcagtat ttgactctga taaaattata gaggcaggat
     8581 ttgattcaac tataataact gtagttacaa atactagcga ttatttggat gtaatctcat
     8641 caaatgatga atcagaagaa ctattaactg taatagtata aattttagga ggggaaattt
     8701 atgaatatta aagatacatt tttctgggga ggaagtattg cagcccatca atgtgaaggt
     8761 tcatgggata gtgataacaa aggacctgca attatggatt ttgtaactaa aggttcttat
     8821 gaaacaccga gagtaattac tgataaaata gaagaaaaat tggattatcc atctcataat
     8881 ggaatagatt tttataatag atataaagaa gatatagctt tatttaaaga aatgggattt
     8941 agtgcattaa gaatatctat agattggtca agaatttttc caaatgggga tgatgaaaac
     9001 cctaatgaat tagggattaa atactatgaa tgtctgatag ataccttaat agaaaataat
     9061 atagaaccta ttgtaactct atatcatttt gaattaccta tgaacttagt acataaatat
     9121 ggttcatgga ataacagaaa acttatagat ttgtatttaa agtacagtga gactgtaata
     9181 aaaaagtttg atggcaaggt aaggcactgg gttacattta atgagatgaa ccatattgac
     9241 cctcaaacag agcactcgga tatttttact tatatgatag caggtattaa gtatagtgaa
     9301 atagaaaata aggttcaaac actggcaaac gtagggtata atatgacttt ggcaggtgta
     9361 aaggttgcaa agttggctag agaaatcaat ccaaacaata aagttggatg tgtatttgga
     9421 ctaaatccaa tttatccata caattgtaat cctagtaatg tgttaaatgc atttttagat
     9481 aatgaccgtg attattatca aattgatgca atgtgcaatg ggaagtttcc tcaatataaa
     9541 ttaaaagaat atgaaaaaaa taatataaat attgaagtga ctgatgagga caaaaaagca
     9601 tttgaagaag gtagattaga ttttataggt cttaattatt atttttcaag tgtatctact
     9661 ccaaaagaaa atttatcagg tgataaatct ttatttggtg gtattcaaaa tccatatttg
     9721 gaacagagta agtggggatg ggcaatagac cctgtaggtt taagatttac tttgaactat
     9781 atttacagaa agtatcaatt acctatctta attacagaaa atggtttagg ggcatatgat
     9841 aaaattgaag aagatggaac tataaatgac aattatagaa ttgagtattt aagtaagcat
     9901 ctatctcaaa tgaagtctgc aattgaagag gacaatgttg aatgttttgg atatttgatg
     9961 tggggaccaa ttgatttggt cagtgcaact acaggtcaga tgagtaaaag atatggattt
    10021 atatatgttg acttagatga tgaaggcaaa ggaagtttta agagatataa gaaaaaatca
    10081 tttgattggt acaaagaggt aataaaattt aatggagaga atctaaattt gctagatgta
    10141 taaaatgaaa tatgtgttat atgtattatg attatacctt cgattattat aaactacaaa
    10201 taaatttaat ttaccatttt tcggtaagtc actaaaataa taaagttaaa caagcattta
    10261 taagtttagt taatgtttaa agtaaaagca ctcttttaaa gtattatcta tatatcagta
    10321 atgttttaaa tgagtgctta tgtaataatt ttgggttaaa tatagaataa aaaattaaaa
    10381 gcagtttact taaaaataaa gtaattttaa tttttatgta tttatactct aagaatatat
    10441 ccttccttac gagaagcagc cttagggtgt ggacaatcag gatatccaag agctatagat
    10501 gctacacctt ttaaagtttc aggtaagccc cattttttta ataattcttt tccttctatt
    10561 gattcaaaca tttcttttgc acgatgtatc cagcaagaac ctaaaccaac tgcatatgca
    10621 gcattcatta aattgccagc aactaaacta cagttttcaa ctggaataag tgcatcttct
    10681 ggagcaagaa taagtaaaat agtaggtgca ccataataag gatgaggtgt tttttctata
    10741 ttaagtatcc tagcattaag tgcgtctaac tgagaaactg tatcttcgtc ttgtaccgct
    10801 attattattg gttcttgtga gcctttgcta gtaggtgcat atgtaccagc ttcaagaact
    10861 aaatcaagct cttctttact tacttgattt gatttgaatt ttcttatact tctacgattt
    10921 tttaaaactt ctaaagcttc ttttttcata ttcatacact ccttatgtta tagtttaatt
    10981 gtagtcttat tagctacaat taaactataa cataaaataa ttgtagcgtc aatagctaca
    11041 attgacaatt tattttataa attatataat actgaaaagg gagggatgcc aaatgcgtat
    11101 gagcactcag tttacagtat cagttcaaat gctattatta ataatggttt tagatgatag
    11161 aaaagtaact agtgaaatga tttctaaaag tactggagga aatcctgtaa tggtacgtca
    11221 attgtttggc aaactaaagg aagcaggaat cttaaatgta tctgcaggta gaggagcaac
    11281 agttctagcg aagaagcctt cagagatttc attatgggat atttatatgg cagttgaaga
    11341 gtatagttca agtgaattat ttaaatttca tcctaaaata tcagagggat gtaatatagg
    11401 acgtttcttt aaagagatat taggtaatca tttagatgaa gcgatacatg caatggcaga
    11461 taagatgtct aaggtgtctt tagctcagtt gctagaggaa tgggaaagtg taaataagga
    11521 gagtaagtaa taattgaact tatttattgt tgatattatt gaaatattaa tattattaaa
    11581 cttgaaggtc atattgagag attatcaata tggccttatt tatacattta gtaatggcat
    11641 ctatataatt ttacttataa tctatatcaa acaagttaat atatataagt attttatcta
    11701 tgacttttat tcttttaata atatatatat aaatttctag caagaaatag tttacatttc
    11761 actactgtgg tgtgtatact actatgaata tttaaacttt tcctatagaa ctttaggcat
    11821 attaatatat taatgattaa tatgtttgat ttttaaataa tactaaatct aataaagaat
    11881 tatgttagat ggaaaaataa aaaaactata aattatataa tagattagtg gttatagagt
    11941 aaaaataaga tggcagtaaa ctttaaggta tattaataag aagccacatc tttaatttta
    12001 gcataagatt atgaaatcat aaatttacaa attattgtca gaatacattg acaaatttat
    12061 ggtttgaaat tataatctat gttaagaatt gtttgacaat gtaaaactag tgattttaga
    12121 atttagaaga attatttttt atgtctaatt taggaataat ttaagactat tataggttta
    12181 taatttatca ttaatttaat tagataaata ggttttgtct ctaggaataa gatttctaaa
    12241 aacactagaa agagtataat ttataaaggg gggagtagaa gagaaaaaag tatatctaca
    12301 gaaagactta aaacaagaca tattttaata atgttaatga atctgttttt aagatttgtt
    12361 aaggatttta agaataattt aagactctta taaaatggga ttcttatagt tagaatttag
    12421 ataagtataa gtcttctaag aagtatataa aaattaaaaa tagttatagc gtaattctaa
    12481 atttgtaaaa agatgtataa gattaaaaag aaattaagta tatgaataac tatggttaag
    12541 atttaagaaa ttaaccgtgg ttatatttat tcagatattt taagaataat ttaagacgct
    12601 taaaaatcat cagaaaatat caaacttacc atatgtagcc ccaaatagct atagagtgta
    12661 cattttatga atattctttc atttataaaa aattatttta tttaggagga aacaacaatg
    12721 gaaaattttt ggaatccgct tacttgcttt actgtatgtg taatgattta tgcttttagt
    12781 gagtttttat ctaagaaaac aaaaggtgca atttcaacat tgctatttgt atgtattata
    12841 tttttaatag gattttggac aaatatttta cccaaagaca ttacaggagc atcagggata
    12901 ttagctgcaa tgagcaactt tggtatagct ttattaataa ctaacttagg aacacttata
    12961 aatcttgaag acttatgtca tgaatggaaa acggttgtaa ttgcattaat aggtattgta
    13021 ggaatagggg ttggctgttt aacagtaggt agtatgttat ttggtagaga gtatgcttta
    13081 atagcagctc ctccaatagc aggttctact gttgctggta ttatcgtaac aactgttgca
    13141 gaagctgcaa atagacctga acttgctgca tttgtaattc tagtattatc atttcaaaag
    13201 ttctttggca ttccgataac tacatattgt ataaataaag aattaaaatt taaaagagat
    13261 aatggggatt ttttgaaaga tgagtcaaaa agtaatttta aacttccaaa catgagaatt
    13321 tttaaagaag atttaggtaa aaaatcatct actttagtgt atcttgcaaa gctttcattt
    13381 gttgctatga ttggtaattt tgtaggattg gctactttaa taccaggatt tacacctgca
    13441 aactattatt taaatcccaa catagcatgt ttgttagtgg ggttgatttt tacacgaata
    13501 ggttttttag aaaaaggaat tttagataaa tctcaatcta atgggattat aatgtttggt
    13561 tgtatgttaa tgttacctgg aggacttgct aaggtaactc caacagcatt gtttgggatg
    13621 attgttccaa ctataggaat acttgttgta ggctccgtat ttataatatt atttacttca
    13681 attgtaggca aactattggg atattctcca agaatgtcag ctgcaattgg tgtaacttgt
    13741 atgcttgctt atccagcaac acagataatt tctaatgaag gtattgatgc aatggaagga
    13801 actgaagaag aaaaacaaag agcaacagat tatttgttac caaagatgat tataggagga
    13861 tttgttactg taaccattgc atcagtagca tttgctagta taataggtcc aattatattt
    13921 ggttgatagt aaatagaatt ataggaggaa taggaaatga taggaagtat atctataaat
    13981 gagatagata aaaaaagatt caaacttgat gatttgagta ggaaaatatg ggaaaatcca
    14041 gaaaaagcat ttaaagaatt taaagcatgt gaaaatacag caaatttttt aagaagtgaa
    14101 ggatttgatg tagaaatagg tgtaggaggt ttagccacgg ctattaaagc tagttttggt
    14161 tcaggcaaac cagttatagg ttttatggga gaatttgatg cgttacctgg tttaaatcaa
    14221 aaagtttcaa caaagcaaga agcatttgaa ttgggtgctt atggtcatgg atgtggacat
    14281 aatttattat gtacagcaca tgtaggtgca gtagtaggga ttaaaagaga aatgatagaa
    14341 aataacttag gtgggactat agtattttat gcatgtccag gagaagaaca attaacaggt
    14401 aaaggattta tggctagagg tggagctttt gaaggtttag acttagctat aaattttcat
    14461 ccaaataaaa ttagtgaagc tacaattggt acttcaacag ctgttaattc tgtaaaattc
    14521 cattttaagg gaaaaactgc acatgcaggc tcagaccctc aaaatggaag aagtgcacta
    14581 gatgctgtgg aacttactaa tgtaggagct aactatttga gagaacatgt tacttctgat
    14641 gtaagaatcc attatacaat tacagatgga ggagtagcac caaacatagt tcctgataaa
    14701 gcatcagtat ggtattacat aagggcttta agtagagaag ctgtagagag tacatatgaa
    14761 agacttgtaa aggtagcaaa aggagctaca atgatgactg aaactgaagt tgaagtagag
    14821 tttttaggag gatgttataa tactttaaat aatcatactt tagcaaatct tgtatcagaa
    14881 tgtatgaatg agattaaaca agagccttgg actcaagagg aattggattt tgcagctgaa
    14941 ttagatagac aaagcccaca acaatataag gatatgataa gtaaatataa tttgcaagaa
    15001 ggaactcatc tatattatgg tggaggaaat gttacaaact ttaatagtta tggctctact
    15061 gatattggag atgtaatgca tatagttcca acagcatact tttttacagg gtgtacgaat
    15121 ctaggtgcgc caggtcatag ctggcagttt acatcttgtg caggaagttc tataggagaa
    15181 aaaggtatga tatatgcagc aaaaattatg gctatgtttg gagctaaaat attaaacaat
    15241 ccagagatag ctaaaaaggc aaaagaagaa tttgataaat ctatgaatgg taaaacatat
    15301 aaatgtccta ttccagatga tattccaacg ccttaaaaag atatgaagtt taatatataa
    15361 aattataatt tttatgtcaa catcatttca tactaaaaga aagtgagatt ttactaagag
    15421 tttaggagta tttttatgga ttggaatggg aagtattagt cagggaaata attttggtat
    15481 gcataatcct aaggcaattt ttaatgaata gggattagtt tacggttcag ctttatttgc
    15541 taattatgca gtaaaatggt tagaaaataa ttttagtaga gaataacata aaatattatt
    15601 aaatatcata aaaggtatat cttaaaaaca aatgtcaaga tatacctttt agagaattat
    15661 atataatttt acttaatatc agatgataaa atatttttat gtattttgga ttttaatatt
    15721 tattttctga tataaataat ttgtataccc tttcaggtct accttttgtt gagttttgtt
    15781 tttcatataa tatagtagcg tttccagact ttaagagact acttagaaat ctattagcag
    15841 ttctcactgt tacatttaaa catgaagaca attctttagg agtaacttca tctctttgta
    15901 gaatttcagt aacagatata atcttttgaa tagtaagagt agacaattta gaacttttag
    15961 caattgtatt tatatgtgga gttactttat ttgaaacagt aagtaactta tcacataata
    16021 aaggtcctat tgtctcataa ttttcgttaa ctaagaaact gtagtttaaa gggtttattt
    16081 tagattcctt attagcactt atggcactag acatagcttg ttttatatca ttacctattc
    16141 catatccaat acatacctta atatttatac tattttcaat ggattctttt atataacacg
    16201 tagtaaaatt tttagttaat gatttaatcg tttcacattt agtgaaaatt ttaaaagaat
    16261 tactattttt ttcaattata aaatcggtta acttatcttt ttttatacta tttaatattt
    16321 tataaacttg gtctaaagta gaatcatcat aatttgtatc tttaactgtt atatatatta
    16381 cacttggttg atttcccttc attctatgta aatgaatgtc ttttattaag ttattaaaag
    16441 tattttttaa taaatctata tcaggatata tgaaatgaaa gtttactcct gcatcttgta
    16501 acataggaac aatactacta aaacgagtag tagaaaaatc aattttccct tcattccata
    16561 gattaatatg tttttttgca atcttttttt cgagttttgc tatatcagat aaactcattt
    16621 tagatgcatt ttcatcaata ctatccatta agtctccaaa tgtaccattt gataaataat
    16681 atgatatatc ttttggatta tctgcccagt cagttaagtc aaagtatgct ctagaaaaat
    16741 ctaatgtatt atatttaaag ataagcttta gaaacatatc atagtaactt tgcaaatcag
    16801 taccaaaatc aactagaggt tttttaatag ttccagcctt ttttgtaata gcttttttgg
    16861 ggataggtcc actaactgca aatccatcaa aactatcttc tatttctaaa tacaaatctc
    16921 caacatgaga aaaatctcta tagatatata tttcaatttc tgcattaata tttaattttt
    16981 ttatagaatt atctacaaac tcttttaaaa attcggttgt tatgactgct attttcatca
    17041 tagattactt ccttttcaat tattataatt attttatatt aaatattaca ttaatctatt
    17101 gcgctagtta aaatcatatt tcaattaaaa taaataactc tttataaaaa acaattattt
    17161 agatagaaaa atatttacga actttaatag tctttgttaa ctttgatttt atttaagtta
    17221 ttatagactc gctaatttta taattgtaga tttagctact ttatgttctt ttattgttta
    17281 tgttgttgat ttagaagtta ttttaagtac ttattttaat tgaagttgtt tgttttttaa
    17341 aatcctttgt gtaatcttta tttttctagc cataataaaa atatttgtat ttgtatcact
    17401 atatataata atatcatgac aaaatattta ttgtctaact aattataatc tattcaaaat
    17461 gaaaatggga atgagatatt attacaacaa gtcgtattat tattaaaatt gattaaataa
    17521 ttaaatgatt aaataattaa atgattaaat gattaagtga ctgttatata acaatttgta
    17581 attttattta acagccactt aggtatttaa gagcaatgga attgagtgta tatcaaatta
    17641 taataatttc ctagtaaata attgaaaaat aaggtaatcc atttttatat ttgatatctg
    17701 gcttaccttg aataagtgga tatagataat ccagtgcttc gtcagttata taattacatt
    17761 cttcatttat ccactcttta gggaaatact ttgtcttgtt agctatttta gaaatatcag
    17821 tatgaccaac ttcatactta taaggattat tgcatgttct attaatgata gccataactc
    17881 ctgtatattc ttttttagat agctctatcc catatgcacc aacgtcagct gcttgtttta
    17941 aatcagtacc tgaagctaaa tgcatagcac atctttgtat tacaccaagt tctaaagttt
    18001 ttactcttgt tgtaattgat gatgatacta taagattctt tagatagttg ctcactccac
    18061 ctaattgaga atgaccaaat ttatcgtgag cagaagtttt ttgttcgcat ataaagttgc
    18121 cgtatttatc tcttatacct tctgatgcaa ctatataagc cttatttttt tctttaaata
    18181 tttttctaac atcttctata aacttatctt catagaaatc aatttctgga aggtatatta
    18241 aatcaacaag tggagtatca ttaagtctag ctagtgaaga agaagctgct aaccatccag
    18301 tatctctacc catagtttct aatataaata tcccattatt tttatatata gaaaaatcta
    18361 agtacgtttc cattattagt gtagaaataa gctttgcagc agaaccaaat ccaggacaat
    18421 tgtcagttcc caataaatca ttatctatgg ttttaggaat ccctataaat tttattttac
    18481 aagtagtgtt tttgcagtat tgagaaaatt tcattactgt atccatagaa tcatttccgc
    18541 ctatgtaaaa taatgtatct atttcatatt catctagtat atttataact ctatcataat
    18601 cataagaatt tatcctataa tcagctaatt tgtatctaca agaaccaaga ccagatgaag
    18661 gtgtttgctt taaatttaat acattatctt tgtttaaaga gtctgaatct attatatttt
    18721 tatttaatat accttcaatc ccattgatac caaaatacac tttatcaaag tatttagttt
    18781 ctaaattttt ttcataaata ccaattgcag aagcattgat aacagctgta ggacctccag
    18841 attgggcaat aatacagttt ctcattttac atctcccttt cattaatatt gttatgaatg
    18901 atacttttta ttgagcaaat ttatatttat agtctgatta tatattaagt gaactagcta
    18961 tatcaattga gttggtatag ataataaata ccataagaat gtggcaaaaa actaactttt
    19021 tatatacaat taatgtctat aatttaccac aatataaagg tacttttaag gagtagtcaa
    19081 agtgttgtga aaagaaaaat atcagtgtaa tattaattta caaagcaaaa taagttcaca
    19141 gttcacaaaa gcagaataag ttcataaaag aaatacatac agcaataaaa gtaatactaa
    19201 attaaaaaaa ttaaaaaata tcaaaaacta atatttaata ttaattaaag taaaatatgg
    19261 agggacacaa atatgaaaca cataaaaata gcagcaggat tggcacatgt aaattatggt
    19321 catatatcag ccgtagttaa ggaagcaatg gatgcagggg tagactatgt acattcagat
    19381 gcagcagata tgcatgactt aaaaaatatg caacttatgg gtggtcatca aataatagaa
    19441 gcaataagac cagtgacaga taaaccaata gaatgtcata tatacacaag agattgtgat
    19501 agattattta tagaaaaaat agcagcagca ggatgtaact tgttgataat accagctgaa
    19561 catttcttag gggctcctct tgcatacata ataaattact gtagagaatt tggtatgaaa
    19621 gtaggattga cagttggatg ttatacacca ctatgttttg ttgatgaagc tatatatgat
    19681 atagacagat tgcaaatagt tgttcatggt gttgatgaaa ctgatggaaa agataactgg
    19741 ggatggagaa agagtgctgt tgacttagta aaaagagcta gaaaaatgat agacgaaaag
    19801 aatcctaagt gtgaattagc aatagatggt ggactaagag cagacaatat ggagccattg
    19861 atagaatgta atccagacgt tgtaatatta tcttcagcaa tattcaaaga taaagatggt
    19921 atagcagcag gtgttaagaa ttgtagaaaa gctatagatg aagcagctac aaagtttggt
    19981 ttagaataag ataataaact atgataaaag agatgctttc ttaatgtttt aaggaagcat
    20041 taattttatg aaaaactaca ggaagttaga ctaatttaat tgatttttta tactgaaaga
    20101 atataatcat tggaggttat taaatgaaaa aagaaatgat aaaggattat ttactgataa
    20161 cagtatcagc atttttaatg gcattagcag ttaatttttt ctttgcagaa catacattag
    20221 ccccaggagg gataacagga ttatcagtgg tacttagtac atttttatca atgcctgttg
    20281 agaatatatc attaggaata tctatgccac ttttagtaat gggattatta tttttaggga
    20341 aaggttttgg aataaaaaca ttatatataa ctcttatggg tccattcttc ttaaaagtaa
    20401 taccacaaac tcacataact gacaacctat tagtagcagg agtgataggt gggttattgg
    20461 taggaactgc tataggtata gcaataataa gaggttgtag tactggtgga actgatttag
    20521 ttgcaatgct tattaataaa gtaattaagt ttctgaagtt gccagttata ttatttatgc
    20581 tagatggatt tataatagta gcgtctggaa taataagtaa gaattttatg atatctatat
    20641 attcattgat atctttatta cttataataa aaacaatagg atttgtaact acaaagtttg
    20701 gtaagaatac tgaagaaatt aataatataa atagtacttg cactcaataa aaataataaa
    20761 acttacttta aatataaaag tttaaataag aagtttaaat gtaaaaatgg aggtgtctca
    20821 aaataaattt tttagttcac gaggcacttt ttttctatga aatcaaatat atttttatca
    20881 tgtagacaat gaaaactagg cttatcttta tgttgagaca agcctagttt tgtttattta
    20941 taggataata ttttattttt ttcagaatac aattttttta taattgtact aagtctggaa
    21001 atatcattct tgcttaaaag agcatttata tttatcagtt cagcattatg ttcaaagtcc
    21061 acaggagcag tggttagtat taagtccaca tcatcaaagt tcgtaaatga aatagaagat
    21121 agaggtatag atttaactat attaatctga ttaaattcaa aacttagttt ttggactaat
    21181 aagttagata caccatcact acaatgacat attaaaatag tatttagagg agatttactt
    21241 ctatctattg ctgatatcaa atataaagca agatacccta tttcgtcatc attaacttca
    21301 taattcatca actgtttaat aacagtatta gattctttag cagccttata tgtataaggg
    21361 aatgtcctct ttatatcatt taatatggga tttgtaatag taaatccata gtttattctg
    21421 tgtagaactg atttaaggtg attagcaaga gactttatta atattaaatc atcttttaag
    21481 tttaaattta gtatatttcc ccaatgaaca gctattgctt cagatagatt atactctgta
    21541 atttcttcat ttttaagagg ttcaagagta gtagttttct ttattgattt gagcaatcct
    21601 tctacatgaa gaaggatata acagacctct tcactaataa attctacatc aaaagcttca
    21661 cctaggttag aacataaaat ttttgatttt tcaaagtatt catgttccaa taattctcta
    21721 aagaaacctt cagataagtt aatatatctt ttaattgaaa tcctcctaat acatatagct
    21781 atatgtatta agaaatttat ataatactca tcactaaggt tacttttttc tacttgcaaa
    21841 gtttgtagag ttatttgaga taacttctca aaatcatagt taaataactc cttaaatatt
    21901 tttgttgatg gagtatcttt acattcatta gattttgaga ataatatttc tttaagctca
    21961 gtataacttt tattaacagt agcaagctca aaaattgctt ttcgaatatc tttctctttt
    22021 ccctctaaat atactccatt attggttttt ctaactaatg ttactttaaa gttttgtaaa
    22081 aaattttgaa taactaccaa gtctttatgc acagtagctc tgctaacatg tagttcattg
    22141 caaatatcac gaatcctaaa cttagaattt ttaataaata atttacttag aatatacctt
    22201 tttctatctt caggagaata tgcatatata caatttgatt tatcattgat atctctaata
    22261 actttaagtt ttatatcttc attacctaga ataataactc ctgaaccagt ttttttatcc
    22321 agggataaat taaactctaa aagccattca tctaaaataa caaggtcatt acgaatagtt
    22381 ttattactaa catttaattt ttcggcaata gtatctacag taatatagtc tgagctgttg
    22441 agtaataatt cagcaatatc taataatctt ttgttcaatg caaaccctcc taaatcttag
    22501 ttactattta ttaaccttgg accaatctct ttcaaaagta ttggcaccat ctactgtaag
    22561 ctggttaaaa gaagcttttt taaataaatc atatgttaca gctgcataat cacatccaca
    22621 aagagatgct tgagttaaat ggaatacatt ttttatagaa gctgcaacaa ctttagtatt
    22681 atatccattt attgatataa ggtcacatat ttctgtaagg ttttttatac catcattccc
    22741 attttcatca tttctaccta taaaagggaa taggtaatca gcacctgcat ttatagctaa
    22801 tgatgcttga tttacattga aaatcaatgt acatgcagtt tttacacctt tactatttaa
    22861 tatgtttata agttctaagc caatttcaga gaaatttatt tttattatag tgtctttatt
    22921 tatatttaat atcttatcac atgaattaat taattcgtat aaattatttc cgattacttc
    22981 agcagttaat atttctggat ttagattagt acatgtctca ataaactcat agaagtttat
    23041 attttcttta agatacatag atggattagc tgttattccc ttaaatccac actttaaaca
    23101 cttttgaatt tcatcaagat tagcactgtc tatcaaatat ttcataattt aattctcctt
    23161 taagcttatt tgtcataaaa aagtgtatat actctatttt tattattaag tcaattatac
    23221 aataagattg attataaaat tataacatgg gtacttaata aaatttacat aatgatatgg
    23281 taataataaa acattgattg tctaataatt gccataagct ttagtaaata agagttaaca
    23341 gtgaaggtat tgccttaaaa atcctatgat atgtataatt tgaatatgaa ggcaataatt
    23401 taagggagga aaaatatgat taacttttat caaccatcaa gaataaattt tggacaagga
    23461 actataagtg agttacctag aataatagga aaatatggaa agaaatgttt gttagttact
    23521 actccaaatg tagagccatt agacaagcta tataaaagag ttacattgga tttaatagaa
    23581 aaaggtatag aagttgtaca ctttgataga gtagagccaa acccaactgt agaattaata
    23641 aatgaagggt ttgaattagc taaaaaagaa tctgtagatg ttgttttagc tgttggtgga
    23701 ggttcaagta tagatactgc aaaagtatta gcattgactt ttggtttaga aaaaatagat
    23761 tgggattata tgtttagtac atatacaaat ccatttaaaa tatacgataa ggtaagtgaa
    23821 aaagaattac cattaatagc tgtatcaact acttctggaa caggaagcca agttacacaa
    23881 gcagcagtaa tatcgagagg aagcgagaaa aatacaatat ttcatcaaaa ttgtttctca
    23941 aaagaatgta tagttgaccc agagcttatg ctaactcttc cagagagaat tactgcatca
    24001 acagcatttg atgcctttac tcatgcgttt gaaagttata taaatccaaa tgctaatgac
    24061 tttacagaga taatgtctga aaagtctatg gaattagtca ttaactattt acctaaagta
    24121 atggaagata aaaataatat agaatacaga acaaagttag cagtagcaga tacattaggc
    24181 ggaagttcac tggcaaatgc tggagcagca gcaccgcatc cactaagtga aataatagga
    24241 ggagttacac atattcctca tggcgaggct ttagctatag tgtttccaaa atttgcagaa
    24301 aagttctata aagataatgt agataaattt gctaaagtag cgagaatgtt aaaccaagaa
    24361 ttggaaaaag tggaagataa tgaagcagct aaaactttag gaaaagaaat agaacgtttt
    24421 ttaaagaatg tgggacttaa gacaaaaatg tctgagttta atgtcacaaa agaacaatta
    24481 gaacaaataa cgagttgtcc agttttagga tttttacctt ttggaaagaa ggaagacctt
    24541 gttgaaatat tagaaaaatc ttattaggat gtgatacaaa tgcgatataa attaatttgt
    24601 accgatatgg atggtacttt gatgggtaaa ggatttgaag tatcagaaga aaatattaaa
    24661 gcattaaagg aagctatgga aaagggcatt aaggtagcct tagtcacggg aagaccttat
    24721 aatgctataa aatattttac aagtgtttta ggagatgata tatatattat atcaactaat
    24781 gggacatatt ttaaattact gggatacgag tataagaagg ttttgagtaa agaagctcta
    24841 aagaaaatat atacaatagg tgaaaaatat aatttaaata aacattttaa aggttgtaaa
    24901 atagttatat ccaacaatga aataggtcaa gaacatccat atagattaat aaatagtaaa
    24961 aataaagaag aagacagaat tgaaataata gaaaatgcaa gttgtgaaac tttattagaa
    25021 aaagctgata atgagatttt aaaatgtata cttttctcag aaaacgtaga gtctttaaga
    25081 gaagcaaaag aagaatttaa aaaacaagaa gatttagaag tagtaagttc tggaaagata
    25141 aattttgaag ttatgagtaa aggtacttca aaaggtattg cagttaaaaa attttgtgat
    25201 atattaggta tagatagcaa agaagttatc tgtataggtg ataatgaaaa tgatatatcc
    25261 atgattgaat ttgcaggtct tggtattgct atggggaatg ctacagatga agtaaaatct
    25321 atagcagact ttgtaactga tactaatgta aatgatggtg tagcaaaagc tttaagaaaa
    25381 gtattatcat aaaattttat aatgtggaga gtgtgttatg tttaatatat ttaagaaaaa
    25441 agaaaataag gttgagaaaa tatacagccc ttttaaggga aatttagtta acttagaaga
    25501 tgttccagat gcagtttttg cacaaaagat gatgggagat ggagtagcaa taataccaag
    25561 tgaaggtaag ttatattctc ctgttgatgg tgaaatagtc agtgtgtttg atacaaagca
    25621 tgcaataacg attaagagta atgataacac aaatatgttg atacatgtag gtttagagac
    25681 aatgtcacta gaaggaaagc cgtttgatgt taaggtaaag gcaggagata aggtaaaagc
    25741 taaagattta ataatggaag tagatttaga ttttataacg tcaaatgatt taaatataat
    25801 aactcctgta gttataatgg atgatgctga ttctgttaag agaacagtaa aagataggat
    25861 agaacctgga aatgtagata ttaatagcat aataatggaa gttgaataga tataaaaagg
    25921 gagttgtctc aaaatttatt ttactaatca aattttaagt tcaacttcct ttttggatgt
    25981 gtttttttga tattcttttt ttcttttgca ttatttatat acaaactcaa ttttcatttc
    26041 ttagattctt caaaaagtaa atctattatt tatttcatca tattctacaa aagtatttca
    26101 taacaagtta gagcaatttc atgaaaatat catcattata atgaaaaaaa gaaaatgttg
    26161 atacagatag tatcttttgt tgttttttga ataaaacaga aattttaaag tgaactttaa
    26221 gactattctt attcagaaag tgatcttcat aaaaatgtat ttttataaat ttatgttgtc
    26281 tgtaataatt taattattta taattaaaag ttgttatttc tatgaataaa ttactttata
    26341 tttaatcaaa tgttataata caattaaaat gtattaatat ccaataacag ttagggggat
    26401 tctaatgatt aatattgcta tatgtgaaga taattttgtt gatagaggta tattaaatga
    26461 ctacttaatt agaataatga atgaaaactc atataatata agtttattca aaagtggaga
    26521 agagttactt gataattatc cagatgactt agatatatta ttattagata ttctgatgaa
    26581 aaaaataaat ggaatagata cagcaaaaaa aataagagaa tttgatagta atgttgaaat
    26641 tatatttata acatcattat tagaatatgc gttacagggg tatgaagtaa aagcttttag
    26701 atatatatta aaaccaattg aatatgaaca actgtcaatt aatatcatac aatgtttaga
    26761 tgatattaat aataaagcaa gtaagtttgt atatataaaa tgtaatagcg acatagtaaa
    26821 gatagatatt gagtcaattt tatatatcga aaaaatatca agatatattt ttgtatatac
    26881 tgaagatcaa gtatataaat ctaaaatgaa tttaaaggac atagagaaaa aattgcaaca
    26941 ttataaattt tatagatgtc atttaggtta tttagtaaat gtaaacaaaa tagattgttt
    27001 aggctcaagt gaagtaagta tatataatca tagtattcca gtaagtaggg gaaagaggaa
    27061 gatattaaaa gagtttataa ttgattcgaa agaaaagagt ttataattat gtatttgtat
    27121 gagatatgga ttattataaa cttcatttca ttgatagtag actttttaat tattaataaa
    27181 atttttactt atcttagcaa gaagaaaaca tctagaaact ttatgtttat cagctttctt
    27241 attgttataa ttatcttatt ttttttaaat tcaaattcta ataatgaacc catgatatat
    27301 atttttttta gcataatttt gtattatata aactatgaaa ctagtttagt taaatcaata
    27361 atagtaccat cattatattg gataatatat cttttcttaa ttaaatatat ttcttctgtt
    27421 ttagttatta atattaacta cacagaacag caagtattaa aaggtgatat atttgcatta
    27481 gagatgatgc tattagcata tattttctta atttttttag tgtttataat aaaatttgtt
    27541 gttacaaaaa ataattttat aaaaaatata catttaatat tttttacatt tataaatata
    27601 gtgagttttt tattaatatt tagaggtgca gccaaagata taaatgtaaa ttttgtagat
    27661 aatatattca taataattat aggttttaca attgtgatat ttaatttata tttattatca
    27721 atgatggata aacttctaga aagtagacga attgaaatag aaaataaatt tatgaaagaa
    27781 aaaatagaaa ttgaatataa gtatataaaa aaactgcaat atagcaatga aaatataagg
    27841 attttaaagc atgatattaa aaatcacctt atttgtataa ggaatataca taataataaa
    27901 gaagcatttg ataaatattt ggatagtgtc gatattgaag ttaataaaat aaatgatata
    27961 tatgacactg gtagtataat tgtagatgct atattggatg aaaagaaaat tatatgtgac
    28021 aattataata taaagttata tgtaaaggca aattttacag gatgtgattt cattagtgca
    28081 tttgatttat gtacaataat gtcaaaccta ttagataatg caatagaatc aaatcttaaa
    28141 gtaaaaaatt cagattgtag aaatataact gtaaaagcaa attgtgaaaa atatatgctg
    28201 ataataatag tcgaaaataa taagtctaat aaaataatta aatctaaaca gagtataatt
    28261 actgataaaa aaaataaaac tattcatgga ttaggattaa aaagtgtcaa aaagtctatt
    28321 agtaaatata atggagattt atttgtggaa tataatgatg aaaattttaa agttaaaata
    28381 ataataccaa caaatatatg acgagttatg cacgaaaaat gacaatctat gtacaatatg
    28441 ttgataaagt aagatgcata aactactatg taattacaaa ggggggtaat aaatatgata
    28501 aaaataaaaa aaataacaga taaggaaaag gttgttgttt cagctcaagc aaaaaaacca
    28561 tgttcatgtg caggtcaagt attaaagtat ccacctgtaa gtaattcttg tttatatgat
    28621 tatgatgact ataatcaacc tagatggtat gaggcacaat gtcaataagt aatactaaag
    28681 ccacttttat aatataaagg tggctttatc tataaaatat gtctttattg ggaggagaat
    28741 atgaattata aatttgatga tagtgtaaaa cttttaaaaa atggagaata tgtaattctt
    28801 ggtaatacaa agaatggtca atggattaaa atgacaaatt atatttataa tatatttaaa
    28861 ataggaatag ataactcttt agatataaat gaattaaaaa aatgtttaga agatgatgaa
    28921 gatagacaat ttatacaaaa tctttatgag aatctattag acatgagaat aatatatgat
    28981 gaaattaata atgtagcttt tcaaaataag atagcctctc ttgaaataac aaatagatgt
    29041 aaccttaaat gtgttcattg ttgtgtagat gcggataatc ttataagtga aaaagaagag
    29101 ctgtctacaa tagaacttaa ggatgcaata aaaaaaatag ttgaatggaa tcctatgaat
    29161 attatgttaa gtggtggaga acccatggta agaagtgatt tttttgagat actaacatac
    29221 ttgaagtcta tatataaagg aaacataata gtttcaacaa atgcgactct aataaataaa
    29281 aataatgtag agttattaat aaaaaatgtg aataagctag aaattagctt agatggagta
    29341 aatgaacaaa cttgcagtat agtaagggga aaaggtgtat ttaaaaaggt aattgatagt
    29401 gttaatctta taaagagctt tggtttcgat aatataacac tatcaatggc tgtaggtaat
    29461 aaaaatgaat atttagaaga agaatttaaa gatctatgca aaaacttggg agtagggcat
    29521 atgataaggc gatttggtcc agtaggaaga ggaaaagaaa atgaacattt atttttagat
    29581 aataacaaag atgaagctta tatacctgaa aattttttaa aggataatta tgatggaaat
    29641 atgggtgtaa catcttgtaa agcaggtatt tatgaaatat ttattagaca caatggagat
    29701 atatatcctt gtccatcatt tatgtcagat gaatataaaa ttacaaattt atgcgatata
    29761 caacaaataa gtgagattaa agataaatat ataaataaag tggatgtatt ttctatatta
    29821 gaaaaaataa atccagaaat ttataaaaat tgtatagatt gtaatgtaaa tttattttgt
    29881 tggacttgtc caggagaaat tgaagaacta aaagatagta aagcaagttt atttaataag
    29941 tgtagtaaaa taaaaaatat tttatataaa agagtgtggg ggaatgatgg agtatgttag
    30001 caacattttg gattacaaat gaatgcaaca tgaaatgcag atattgctat gaaggtaata
    30061 ataagaataa taaagttatg tctaaaacgt tgatagataa atcaataagt tatgtattaa
    30121 atcaatctaa tagtttggat gatgatgaac ttgtaataca aattcatggt ggagaaccat
    30181 ttttagaatt taacttgata aaatacataa taagtgagtt taaaagcgaa aaatttaata
    30241 aaaatataat attttcaaca actacaaatg gaatgctctt gaataatgat attttagatt
    30301 ttatacaatt atatattgca gaattaacca taagcataga cggtgctaaa aatacacatg
    30361 ataaaaatag acaaagtata aatggaaaag gtacacatga tatagttata gaaaatagta
    30421 gaaaaatttt aaaaataaaa ccaaatgtaa gagtaagaat gacatttgat acagagacag
    30481 taggtaattt atctaatgat ataaaatatt taataagcga aggatttaga acgattgttc
    30541 cagttccaga tatgtttgag actagatgga acaataatca tatagaggtt ttgaaaaatc
    30601 aaatatacca aataaaagag attataggta acagtaaaga tattcttgta agcctcacag
    30661 acacaaacat atataagtat aaaggtgttt gctctggagg aaagttaagc tttaatatat
    30721 gtccagatgg atatatatat ccatgcacat tagcagttgg aaataaagat tttagtatag
    30781 gaaacatata tgatggtata gataaaacta gtagagacaa gtttttgagt aaatcatacc
    30841 tagataataa cgattgtaaa gggtgtgact taagcaattc atgtgatgga aatagatgta
    30901 agataataaa taaattaact agaggttcgt attttttacc atcgccaata aattgtgcta
    30961 tacaaaatat aaaacatgag ataaatataa gtaaagaaat tgtattatag ttttgtagag
    31021 ttaaggagga atagcttgaa acgaattaag gttgcattaa ttgactcagg tatagatatt
    31081 aatcataaat atttaaagaa taatatattg tatggcaaat catatattta taaagataat
    31141 aaaatagttg tctcaaatga aattgaagat attaatggac atggtacatc atgtgcatca
    31201 attataaaaa gcgaatatga atatgttgat tttataataa ttaaaatatt tgatagagat
    31261 ggattaacaa atatcaaagt actagaagaa tcattaaatt acttaataag tattgatgta
    31321 aaaattataa acttgagttt agcaatacat ggagacatta attcttgtaa agacttatat
    31381 aaaatatgtg aaaaactaaa gaatcaaaat aaaattatag tttcttccct tgcaaattat
    31441 aattatatag aagagagcta tccatctata tttgataatg taataggagt aaaaggaaat
    31501 ttattaaaaa aaagatcatc attttggtat aattcagaat ataaatatca atgtgttgta
    31561 gacgatagtg atagaatagt tgcagattta ggtaacagtt ttaagttagt tgaaaaaagc
    31621 aacagttttt cggctgctaa aatgagtgga aaaatagcta agataatagc aaataaagtg
    31681 gatataagtt ttgatggatt aagtagaata ctagaagaat tgtctgagtg tacaaattgg
    31741 aaagacgaag atctatatac taataagaga agaatagatt acaaacagta tttatatgaa
    31801 aacaataata taaatcttaa ccgagtatta aaagtgttgg ttgataatct taatattggg
    31861 tgtaatgtgg atattttatt tgatagtata ttatttagta aatatatagg tctaaaaaat
    31921 aataattgta ttgaaatcct aaagaaacta gagaatgaat ttaatataaa gattgattac
    31981 acaaaagtat ataaagaaga tctaatatca atatatactt taactaattt gattgaaaag
    32041 gagagtatat gtgaacattt tagaaactgt aaatatctcc aaaagctata gtataggcga
    32101 taaaaaatca tatatattaa aagatataaa tataaaaata aaagaaggag aatttatatc
    32161 tataataggt cctagtggaa gtggaaagtc aactttactt cacatattag ggggattaga
    32221 aaatcctact actggtattg taaaaattat aggaaaaagt atatatgatt tatctgagat
    32281 taaattggca gaatatagaa gaagaaggtt tggatttata tttcaacaat ttaatctaat
    32341 accagtactt aatgtaagag aaaatattga aatgccatta atgctagata gagctaaaat
    32401 tgataatagg ttcataaaag aaataattga gtttttaggt ttagaagaaa aagaaaatta
    32461 ctatccgaat caattatctg gagggcaaca acaaagagta gctatagcta gagctttagt
    32521 aagtaagcca gatattattt ttgcagatga gcctactgga aacctagaca ctaaaaatag
    32581 tgatgaggtt ataaaacttt taatgaagtc tatacacaag tataatcaga ctgtattatt
    32641 aattactcat gattataaaa ttgctaaaaa cacagataga acaattaaaa tactagatgg
    32701 gaaactagaa ttataaatga tacaatgtca agagggtaat aaattgaaaa atactattaa
    32761 tatgaaaaag tttctatatc tcataattca aggtaataaa aagctagtaa ttatatcttt
    32821 tcttatgatg atagtagtag caatgataga tttgtatata cctcaaataa taaggaatat
    32881 attggatata gctataaaat caaaaaatat tactatgcta ataaaactaa tattacaatt
    32941 tatattaatt aacataatat tatctaatct agaactattt ctggaatata attattctaa
    33001 aatgaagaag aaaataacta caaaattgaa gttaaaatta ttgagacatt tatcaaagtt
    33061 agacggacgt tttttctctg aaataaaaac aggaaatatt atgaacatag tagagtatga
    33121 tgtaatgatg ttagacagat ttggaataga attaatattt tcattaattg tggacataat
    33181 aactgcattt atatcgttgt attttttaat aaagatacaa tcaaaacttt tagtaatagt
    33241 tgtagtaatt caaattgtaa tttcttttac tcaatatata tttacaaaga tgatttctaa
    33301 gtatacacag aatataagaa gtaatgctgg aagtatatct aatatagtac aagaatacat
    33361 atctaatatc atgaatgttg ttatacataa aggtgaactt aattttttta cgcaatttct
    33421 atcaatgcaa aagaattttg taagtaaatg cataaagcta gatatgatta tggctggaaa
    33481 tgtttcttta tctaagatat taaacagttt aattgttatt tctatatatg gttatggtgg
    33541 atataaaatt ataaatggag aaattacgtt tggagaattg gtagcttttc aacaatatac
    33601 aggtatgctt attggccctt gtatgaatat aataaaatct aatgctattg tacaacaatc
    33661 attagtatct attaatagaa tatttgattt attaaatgaa gaggttaata tgaagcaaga
    33721 aaatacaggt gaaatatttc agagtgggat aactaaaaaa attagaatgg atatgataga
    33781 tgtaagtttt tcatatgata aagaagacgt attacataat ataaatatgt cactggagag
    33841 tggtaatatc tatggaattg ttggaggaag tggttcagga aaaagtactt taattaaact
    33901 aatatataga ttatgggata ttgaaagcgg aagtataaga attaatgatg tagatataag
    33961 agattataat ttgaaaaatt taagaaaaaa tattactatt atcacacaag aaccattatt
    34021 attgaatgat actgttttta ataatataat tttaagcaac aagaatatta actatgagct
    34081 agtagtaaga atatgcaagg aattagatat atatgatttt atagtaagtt tacccaatga
    34141 atttaataca attgtaggag aaaatggtgt aaaattgtct ggtgggcaaa aacaaagaat
    34201 ttccatagct agagcaatgt tgagtaattc aagtattcta gttcttgatg aggctacatc
    34261 tgctcttgat aatatatctc aaaaagattt attaaaaagt atgaaaaagt tcttaaataa
    34321 taaaatagtt ataataatag ctcatagact atctactata aaagattcag ataaaatatt
    34381 tgtaattaat aatggtgaaa taattgaatc tggaagtcat aaagatttag tgtctcaaaa
    34441 tggatattat tgtaatttac ttgaagataa aaaagaatat agttactgtt gatgattaga
    34501 tagtcaataa aaattctatt tttatattag aatatattga ctattttttt gtattataaa
    34561 tacaatgtat gaatgaataa gtacaaggta tgtaacattt attgatatat atttattaaa
    34621 atgatacatt tatttcagta attacataaa ggaggaattt tatgagacta tctctagcat
    34681 atgtaaaaaa atactttgga aggtcaatat ctatagcttt aagcataatc attagtatct
    34741 cacttataat tacagttgga atacttacta aaaatactca aaaagcaagt gttgatagaa
    34801 taaagtatga atctggagat taccatgtta aagttaagaa tattagtgga aatgtaatat
    34861 cggattataa aaagcaattt gatataagta tgatgggtgt atcatcttat tacgattcaa
    34921 gtgaatttaa tggaaaatta atgttaaatt taattaaatc taatgaagac tatataaaaa
    34981 tttataattc aaaaattcta aatggaagat ttccaactag tgacaatgaa gttgctttag
    35041 aagaatgggt tatgttgaat ttaggtctaa aattagatat aaatcaaaat ataaaaataa
    35101 aattatataa tagcaaagag actaaaaatt ataaggtagt aggtatacta aaagatagac
    35161 catattacaa atctatagga atggcggaac taatacttcc ttttacagaa aatataatca
    35221 aagaaacgaa tctagaagct caaataagat ttaaaaaaga tatatataga aacttatcaa
    35281 aactaatgaa tgataatcat ataagtagaa aaaatgtatc tgaaaataga atactattag
    35341 atgccttagg agaaagtaat ggactaaatt acgattttat atttacatgc attatatcaa
    35401 tgattgtatc tggagtagta atttattcta tatttagaat atcaataatt caaagaattt
    35461 cggaatatgg aattattaga gccttaggag caaatatatt caatgtattt aatataatat
    35521 ttgtagagct ttttgcaatt tctttagtat ctattccaat tggagttttg ataggtatta
    35581 taagttctaa atatataacc ttatttatgg gaaatttact tattggcaat atagtaaaaa
    35641 taaataatgt agaaataaat ttagatgtag tgatgatatc tataataaca gtacttgtaa
    35701 atatattaat tataagtttt ttaacatgta caaatgtaaa taaaatatca cctataaaat
    35761 gtataaagaa agatatatct aaaaaaaatt ctagagaatc aagtatatta aatactagga
    35821 gattactgaa tcttttaccc atagaatata taatatcctt aaaaaatatt ttaaaaaata
    35881 aaaaaaattt tgtgattata gtattgtcta tgagtggagg gtgtattata tttatattga
    35941 ctaattttac aaacatattg gatgaaagac aactagaata tacatctaaa gttgcaacag
    36001 aaaattcaga ctataatata agctttgcac ctgttactcc attgaatata ggtatatctg
    36061 aagaaaattt aaaacaaatt agacaactag aaggcattga aaatgttaaa acatctcaag
    36121 ttatgtattc aagaatgata ttaaataaag ataatataaa taatatgaat tattttgaaa
    36181 aagtaaataa gtctgcttat aataagaagg ctttaaatgg attattagtt aaaaaagata
    36241 acgagtatat attaaagagc aatctatatg gttatgataa ttcatcaata gatgctcaaa
    36301 aatcctttgt tatttcagga gatatagatt tagataaaat gaataatgga aatgtggcaa
    36361 tactttatat gccggatcct agtttattta caaacattaa agattctcga ccagttctta
    36421 atttaaaggt aggagatatt gtaaaattga ggtttagaag tgattatgta tcagatgaaa
    36481 attttgcaaa attgaaagat aaaggagaat atgttgagga agaatttaaa ataggtgcaa
    36541 tagttagtaa tattttaaat gtagatggtt attatgcagg tatggacagt gcgtctataa
    36601 taatatctca aaatcaattt aaaaatattg taggtataca tagttataga atgttagata
    36661 taaaaaaaat accaacagtt gacaatatag agcttggaaa aaacataatt gacatatcta
    36721 gtaaaattca aggttcgata gttagagact ttacacaaga gataaaaaat ataaaaatta
    36781 tagaagataa taaaaaaatt cttatataca caataatatt agtccttttt acaattagtt
    36841 ttataaatat aataaataat ataaattata acttatactc tagaataaat gagtttggtg
    36901 taataagagc tattggattg gataataata gttttagaaa gatgctatta tttgaaggtg
    36961 ttgtttatgg acttatatct gctagtgtgt ctattacctt tggaatttta ggtcaatcta
    37021 tactctacaa tattttaaaa ggtaatttaa tgaatgccaa atttataata gattataaat
    37081 catacatatt ggtaataatt ttaactatta ttctgggagt agtggcaaca tatttaccat
    37141 ctaaaaaagt taagaaatta tctattattg aatctataaa tattattgaa taaaatcata
    37201 agtaaaatac atttatgctg tgtaaatagt aattactagg aaataatata aaaaataaat
    37261 aaaa
//
LOCUS       DAMKOJ010000039        36704 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000039 DAMKOJ010000000
VERSION     DAMKOJ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36704
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.041"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            258..1298
                     /locus_tag="PC592_002008"
     CDS             258..1298
                     /locus_tag="PC592_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4055981.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFARIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKIIE
                     YFKLNNINIKLLEENDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1654..2976
                     /locus_tag="PC592_002009"
     CDS             1654..2976
                     /locus_tag="PC592_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF4055982.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWSVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3273..4634
                     /locus_tag="PC592_002010"
     CDS             3273..4634
                     /locus_tag="PC592_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF4055983.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGAQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSVTSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4707..6101
                     /locus_tag="PC592_002011"
     CDS             4707..6101
                     /locus_tag="PC592_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4055984.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKRVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMIELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNIILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6163..6633
                     /locus_tag="PC592_002012"
     CDS             6163..6633
                     /locus_tag="PC592_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HDF4055985.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLARNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6636..8852
                     /locus_tag="PC592_002013"
     CDS             6636..8852
                     /locus_tag="PC592_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF4055986.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGALRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAIKLIKVEYEELPAVFTIQEAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKELGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKRMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLITGAHDMGNGVVTMQTMMVAEILGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKVLILEEAEKLLETSKEDLYLDNGYVISKL
                     NENIKASLSDVAVYSQSKSLRELTVVEDYSSPTGLTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVNSYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8932..9603
                     /locus_tag="PC592_002014"
     CDS             8932..9603
                     /locus_tag="PC592_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4055987.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9966..11180
                     /gene="dpaL"
                     /locus_tag="PC592_002015"
     CDS             9966..11180
                     /gene="dpaL"
                     /locus_tag="PC592_002015"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF4055988.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGKYLAQRLDTDISELGY
                     DKLTSDEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHATAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11306..12493
                     /locus_tag="PC592_002016"
     CDS             11306..12493
                     /locus_tag="PC592_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDF4055989.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNKDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            12626..13996
                     /gene="hydA"
                     /locus_tag="PC592_002017"
     CDS             12626..13996
                     /gene="hydA"
                     /locus_tag="PC592_002017"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF4055990.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDENIVEIGNNLEINGDKVID
                     ATGRIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKAIGNCYCDYGFHMTITCLDKDTFKHMEKLISDGIVSFKMYMAYEGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLNVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCKESLKTVKMAREKNVDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINCLWEGLASGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISANKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKIKCKVEDVFLRGNHVVQSCNVKEQPIGQYI
                     KRKITK"
     gene            14014..15420
                     /locus_tag="PC592_002018"
     CDS             14014..15420
                     /locus_tag="PC592_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4055991.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHTHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTERD
                     MELAKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTTDEDKALKEAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            15493..15939
                     /locus_tag="PC592_002019"
     CDS             15493..15939
                     /locus_tag="PC592_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF4055992.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKEFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            15978..16772
                     /locus_tag="PC592_002020"
     CDS             15978..16772
                     /locus_tag="PC592_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF4055993.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKNLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMSLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVLRMYNSIGGECDGK"
     gene            16762..19053
                     /locus_tag="PC592_002021"
     CDS             16762..19053
                     /locus_tag="PC592_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF4055994.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPSYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSRALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGKTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVKDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKRKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            19054..20367
                     /locus_tag="PC592_002022"
     CDS             19054..20367
                     /locus_tag="PC592_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF4055995.1"
                     /translation="MIAIKSKYLISSADEIYTNYAVVVENDIIKDILPNEEVEIKYKN
                     IEEVIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAVLSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDKFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAHVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWNF"
     gene            20403..21488
                     /locus_tag="PC592_002023"
     CDS             20403..21488
                     /locus_tag="PC592_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF4055996.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            21718..22767
                     /locus_tag="PC592_002024"
     CDS             21718..22767
                     /locus_tag="PC592_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4055997.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     RQEMTVMKEDMSEVKQEINIMKEDVSEVRQEINILKEDMLEVKQEINIMKEDMSEVKQ
                     EINIMKEDMSEVRQEMTVMKEDISEVKQEINVLKEDMSEVRQEMTAMKEDMSEVKQEI
                     NVLKEDMSEVRQEMAVMKEDMSEVKQEINVLKEDMSEVRQEMTVMKEDMSEVKLEVTV
                     MKEDVSEVKSEVNFMQNKINNINKDMSGIKEEVSIANEKLDGIEIKIDSLESEDKSMK
                     EMQVEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELA
                     TSKNWSDIVKLKSVK"
     gene            24101..25459
                     /locus_tag="PC592_002025"
     CDS             24101..25459
                     /locus_tag="PC592_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF4055998.1"
                     /translation="MKAKSTSKFELDGMPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALIFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVAGKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNQINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLIFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKIVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLERFPKFVETLLADSSVVSGAMVAIIIQALYMVKFPKNKNGKVEDKNK
                     SL"
     gene            25566..26360
                     /locus_tag="PC592_002026"
     CDS             25566..26360
                     /locus_tag="PC592_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF4055999.1"
                     /translation="MVTIKEYSVPQSLEEAYKILTSKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEMDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGMLELNEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSILNSAMLKENNTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            26353..28659
                     /locus_tag="PC592_002027"
     CDS             26353..28659
                     /locus_tag="PC592_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF4056000.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDRVRFVGDE
                     VALVAAEDEKIALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     NNNIVSKEFFEFGDVEAKLKESDLVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFALDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTSGKAAEGEILSCELKQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGILKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPRFDKD
                     GRLLTNSFLQYKVPTKKEVGNILVDFAENFDSGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRIRELPMTFEKVYMGMKNNNKQL"
     gene            28798..30075
                     /locus_tag="PC592_002028"
     CDS             28798..30075
                     /locus_tag="PC592_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF4056001.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGTLNVPMSPVFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCIKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFANDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            30258..30980
                     /gene="yqeC"
                     /locus_tag="PC592_002029"
     CDS             30258..30980
                     /gene="yqeC"
                     /locus_tag="PC592_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDF4056002.1"
                     /translation="MKLSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIITTIDGTIIPSICHGIIVCGSHINNENKLVSIDSSILDEIVDKFDLV
                     LIEGDGSKRKKLKGWNTKEPVVYHKTTKTIGILDITSFGMDINEENIHRVEMFKKIAN
                     LNTKSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIKNI
                     KECESEIEIFYGSVKQKFCARY"
     gene            31098..31667
                     /gene="mocA"
                     /locus_tag="PC592_002030"
     CDS             31098..31667
                     /gene="mocA"
                     /locus_tag="PC592_002030"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDF4056003.1"
                     /translation="MINAVIMASGFARRMGVNKLLLDYKGCSIIEHVFRVVNKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANVGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDICGNPVIFPYGKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKIDYERIGGKL"
     gene            31664..32683
                     /locus_tag="PC592_002031"
     CDS             31664..32683
                     /locus_tag="PC592_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HDF4056004.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKDVI
                     KNAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            33021..34646
                     /locus_tag="PC592_002032"
     CDS             33021..34646
                     /locus_tag="PC592_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4056005.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLENKEIQEQLAKMYGKDK"
     gene            34841..35293
                     /locus_tag="PC592_002033"
     CDS             34841..35293
                     /locus_tag="PC592_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056006.1"
                     /translation="MVKKRLVAIVMSLAMISVGNFSYAHSGGHNSSGSHHNKNKSELT
                     YYYYCGGHSAHQHNKGFCPYASAKSNSGVTISSAHNEKNHKKFFSEKEYNKGYEDGCK
                     GLYNLSFTEAKSEDSYEKGYLIGYNEYKAKKVYDVIKKMLDIPMLASI"
     gene            complement(35490..36602)
                     /locus_tag="PC592_002034"
     CDS             complement(35490..36602)
                     /locus_tag="PC592_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF4056007.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDKETGKRKQKNMGIFDKKREASKRL
                     NEVKESLYKDGFLVPNEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPIHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDGIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSIRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVISKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
BASE COUNT        14329 a         3971 c         7068 g        11336 t
ORIGIN      
        1 ataaaaaatt taatagagac ttagattaaa aattattttt atgtaaaata tggcatttta
       61 attgcttatt taatagagga ttcttgtaaa gttaagaaag tatatctatc aaattaaaac
      121 taagtggata tactttttat taagttttgt tttaaaataa tattattaaa ttatagctat
      181 gcttttctgt tatgatataa ttaaatagat aatgtgaatg attattatat agaatactta
      241 tttggagttg atattttatg gacaaacaca gtgattcagt aatgtatggt ggaatggaag
      301 tatacaatat ttggggaaca acaacagtag actccataat tggagagtct gatgtaatgc
      361 gtgctcttaa gaatagaatt tgcaaaattg gaaatagtga ttctactgta gctataactg
      421 gagaaagtgg cactgggaaa gaactaatag caagagccat tcatctcgca ggaaacagag
      481 ggaataaaac attcgttgct ataaactgtg ctgctatacc agaaccttta ctagaaagtg
      541 aactttttgg atatacaaaa ggagctttta gtggagcaga ttcaaaaggt aaaattggta
      601 agtttgaatt ggccaatgga ggggttgtat ttttagatga gataggagat atgccaattc
      661 aactacaatc aaagttattg agggtattac aggaaaagaa gtttgctaga ataggttcaa
      721 atgaactaat tgatatagat gttagaatca tatcagctac taatagagat ttatttgagt
      781 tggttaagga aaataaattt agagaagact tatactatag attgaatgta atacctttag
      841 aggtgcctcc acttagagaa agaggagacg atatacaaat attaataaac aattttatag
      901 acaaatattc gagaaagatg aagaaaaacg tgtaccatat agaaccagat gtggaacaaa
      961 tgctgcttaa gtatccttgg ccagggaata ttagagagtt ggagaatact atagaacttg
     1021 ccttaaatct tcttgaggaa gatggaataa tacataaagg tataataaac agaaagataa
     1081 ttgaatattt taagctaaat aatataaata taaagctact tgaggaaaat gactatgaga
     1141 taagtatgga acaagacata cttacgcttg aagaatttga aagagcctat ataaagaaag
     1201 tgttaaagtt ttacggaaat gatactaagt ctaaaaaact ggctgctaaa aaacttggaa
     1261 tatcactagc tacattgtac agaaaaatag atgtataata attagacttt ttattctcaa
     1321 ttctaaaatt tgaaattata aaattgataa aaaacacttg gaaaactatt ttctaagtgt
     1381 ttttttgtgc aatagtattt tattatccaa aaataaaaaa aatttgaaag aatttaaaaa
     1441 aagaaatgct ttaataaatt atcaaatact aacaaatata ataaaaatta tatatgtaaa
     1501 acaattatgt taaaaaattg gcattataat tgcttcatat taagttgaga tgacaaaata
     1561 aaaaaagaaa ggatgttgtg tgagataata ataactgtca ttaaaaaata gttgggagtg
     1621 ataaccttga gtaaatatca aaaaaatgtt tctatgtttg atattgatgg aaggccacca
     1681 attttaaagt gtttaccact atcaatgcaa catatattgg caatgatagt tggaactgtt
     1741 acagtaccta tagtcgtagg aggagctgtg ggtgttagcc ctacacaaat aacactttta
     1801 gtgcaatatg cattaataat agctggtata tcaacactta tacaactata tccaatagga
     1861 aatattggtt caagattgcc tataattttt ggagttggtt ttacttatgt accaacactt
     1921 gtagcagtcg gaggaaatta tggattagca agcattttgg gtgcgcaatt aataggggga
     1981 gtggctacag tattaatagg gatatttata aaaaagataa gaaaattttt tccgaatata
     2041 gttgcaggaa cagttgtttt tacaattgga ttatctttgt atcctatagc aataaattat
     2101 atggcaggtg gtgtaaatag tcctacatat gcttctatgc aaaactggtc agtagcggct
     2161 ataacactag tggtagttat aggtcttagt caatttgcaa aagggtatgc aaaattggcg
     2221 gcaatatttt tgggaattat agttggatat tgtgtatctt tagttttggg tataataaat
     2281 tttgacccta ttagagaggc aacttggttt gcgataccta aaccacttga atttgggatg
     2341 gaatttgata tgcctgtaat aatttcagta gtaattgtaa gtataatcaa cgctgttcaa
     2401 gcaattggag atttatcagc tactacaatg ggaggtatgg ataggaatat cacagacaag
     2461 gaattatcaa gtggagtaat aggaagtgga atttgtacta tgataggagc tttgtttgga
     2521 ggtttgccac catcatcata tagccaaaat gtggggatgg tagctatgaa caaagtaatt
     2581 agtagatttg tgcttggaat agctggtata tttatgttat tgtcggggtt tgtgcctaaa
     2641 tttggtgcat taatgactac cataccatat tctgttttgg gaggagctac aatatctata
     2701 tttagtatga taacaatgac aggtataaag ttaattatta cagaagagtt gtcatcaaga
     2761 aatattacca ttgttggttt ggcaattgct ttaggcatgg gaataacatc agtcccagca
     2821 gcccaagaag cgtttccttc atttgtaaag ttagtatttg gagaatctcc aatagtaatt
     2881 gcgacattgg ttgcattcgt tttaaatcta ataataccaa ataaaagtct agaggatgaa
     2941 gctaaagaaa gagctgttat ggaagagact aattaagata taatagtttg aaaggattgt
     3001 tcaaattatt tagtatgaga ttgttagatt atttttgata gctattcatt ttaataaaaa
     3061 atttaacaaa taaatatata ccaaataatt aatatttatt taagttgaaa atcggggagg
     3121 taatatttag aaatttgtta attttttata aaaatagctc agtttagctg tgtttatcgg
     3181 ttgagcaata aattcatggt cataaaaata tttatagaaa ataattataa aaatatttag
     3241 tcaagatatt tatgtatggg aggatttatt ttatgaaaac acgtaatact tcaaaatatg
     3301 atgtcgatgg gataccacca ctaaaggaat caataccttt agccttacaa catctgttag
     3361 caatgatagt aggaaatatg gtacctgcga tattaatagc aaacgtggta ggacttaacc
     3421 aggggcaagc aacaatgttg attcagggtt ctatgttagc agcaggtttg gcaacgtttt
     3481 tacaattata tccaatacct ttatttaaag gctttaaatt aggttcaaga ttacctgtaa
     3541 tgatgggaat gagttatgta tttttaggag cctgtctttc agtagccgct aaagatggtt
     3601 tagctgctct atttggagca cagattgctg ctggggtaat tgtattcttt gtaggttttg
     3661 gagttaagaa aattagacat atattcactc caatagtttc tggaactata atagcatgta
     3721 tgggacttgg attatttgca acagctataa agaatttagc tggaggagaa ggtgcacaaa
     3781 catttggaag cccaataaac tttacagtag gagttatagt tgcttttgta ataataatga
     3841 taaataaata tggtaaaggt ttagtaaaaa attcttcaat attaatagga atattagtag
     3901 gttatgctat atctttagtt ttaggattgg ttgatttctc agccgttcag ggagcagcta
     3961 tagtatcatt accaacacca gcagcttttg gattagaatt tagaccagag ttaatagtaa
     4021 tgtttactat tatttacata ataggtatag ctgatatgat gggtgcctgt acaatagcta
     4081 cagtaggagc aatggataga gaggtaactg atgaagaatt agcatcagtt gttttaggaa
     4141 actctgtaac ttctataatt tcatcactat ttgcagctct tccaactgga gtatttagcc
     4201 aaaatacagt aattgtatct atgaacaaag ttacaagtag atttgtaata gcactagggg
     4261 cacttgtatt attactagcg ggaatatctc cagcattggg cgcaataatg acaactatac
     4321 catcttgtgt tgttggtgga gcaactttag tagttttctc atcaatagca atgtctggtt
     4381 tctctattat gagcatggat ggatttactg aagaaaacaa tcttatagca ggtgtatcta
     4441 tagcaacaag tatgggtctt acgactgctc cacaagtttt agaccaattc ccagaaacaa
     4501 ttggaactgt ccttggaggg tcaagtatag tttctggagc aataatagct atattacttc
     4561 agacactatt taaattaaag tcacgcaaaa gtgctgaaaa cgttacttca aatcttgagg
     4621 aaaatattgg ataaatgtat tagatataat atgagaaaac catatggtaa aatgttgtaa
     4681 cgaaagtatt caaaggggga tttaagatga ttgatatact aataaaaaat gcaataattg
     4741 ttacagttaa taaagacaga gatgttatat ttgatggagc aatagctatt caaggtgaca
     4801 gaatcttgga tataggaaat acagttgaca ttgaacctaa gtatcttgat gctaaaagag
     4861 ttatagatgc taatggaaaa gtaatattcc ctggctttat aaatactcat aatcacttgt
     4921 tccaagtatt attaaaaggt ctaggcgatg atatggcact tcatgagtgg ttaaatacaa
     4981 tgatgtttcc atcagcaaaa ttcttaacag aacaagatac ttatgatgct gcaatgcttg
     5041 gatgtatgga aggtttaaaa agtggtataa ctacaatggt tgattatatg catactcaca
     5101 atagaccagg acttacagat ggaatagtaa aagcatataa agatttaggt ataagagggg
     5161 ttgtaggtag aggttgtata gatttaggta ttcacaaaga gcttatagaa gatgtggaaa
     5221 cggttgaaaa agatttgaga agagtatttg aaaaatatca taattcagaa aatggaagaa
     5281 taaaaatctg tgtagctcct tcttcaatgt gggctatatc tgaagaaatg ggtaagatgc
     5341 tttggaatat agttaaagaa tatgattcat attttacagt tcatatatct gaaacagaat
     5401 ttgcaagaac agcaacaaag gatatacatg gagaaataga tataaaatta cttgaaaaat
     5461 ggggcatagt aggtccagaa gtcgtagcag tacattgtgt gtgcataact gatgaagata
     5521 tggaaatgct taaaaagtat gatataaaag tttctcacaa tgtagcaagt aatatgtatc
     5581 ttgcttctgg tgttgctcct gttccagaaa tgttaaaaaa aggtataaat gtgagtttag
     5641 gtcttgatgg tgcagcaagt aataatgcac aggacatgat agagcttatg aaactaacag
     5701 ctttacaaca caaagtaaat aattgtgacc ctctagcaat ttctgcagag aaagttcttg
     5761 aaatggctac aatcgaggga gcacgaactc ttagaatgga agatgaaata ggctctttag
     5821 agattgggaa aaaagctgac ttagtaatat ttaactcaat gctttctcca aaatcaatac
     5881 ctcttcacaa tcctgtatca actttggtat actcagctag tatgcacaat gtagagagcg
     5941 ttttagttga tggaaatata atacttgaaa atggaaaagt aactacaatt gaaagtgaag
     6001 aacaagtgtt gcttaatgca caacatgcag cagaagaatt atgtaagaga gctaatgtaa
     6061 ctaatagaat ggaaggacat aagtggaata gcttatacta atattaaaat aagattgtaa
     6121 taatattcta ttacaacatt agtttatctg taggaggaga aaatggaaaa gataaaatta
     6181 aatattaatg attacatgta tgaaatagaa gttgaaaaga atgaaactct tttgcatgta
     6241 cttcgtgaaa aattaaatct aactggagcg aaacaaggtt gtaatagtgg cagttgtgga
     6301 gcatgtaaag ttttgataga tggagttgac atgaaatctt gtaaacttct tgcaagaaac
     6361 tgcgaaggta aagttatata cactatagaa agttttgcta atggagaaaa tcttcatcca
     6421 atacaagaag cttttataga agttggagct gtacaatgtg gatattgtac tcctggtatg
     6481 attataacaa cacaagctct tttaaataga aatgcatctc ctaatgaaga tgaaattaga
     6541 gaagccttta aagagaatct ctgtagatgt acaggatatg taaaaattat agaagctgta
     6601 aaattatctg cagctagatt agggggtaga taattatgga aaaagtaata ggaaaatcat
     6661 accctctaaa agatgcagct ttaaaagtta ctggtcaaat gaagtatgtg gctgatatga
     6721 aaccacaaaa tgtactttat gctaaaatgc ttttaagccc tgtagcacat gcaaaaataa
     6781 aaagtataga tacaagtgaa gctgagaaag tagtaggtgt tagagctata gctacttatc
     6841 taaatacatc acaaagaaaa tacaatggtg cattaagatt ttatgagcac aatatacctg
     6901 aaaatgaagt tattttttca gatacagtta gatttgttgg tgaccgcgtt gcagcagtag
     6961 ccgcagagac tccagaaata gcagagaaag ctataaaact tataaaagtt gaatatgaag
     7021 agttaccagc tgtatttact atacaagagg caataaaaga agatgctatc tgcatacatg
     7081 gagattcaaa tatagtttct caaaataaca taaatggggg tgatgtagaa aaaggcttca
     7141 aggaatgtga ctatatattt gaagatgaat actctactcc agcaatacat catagtgcaa
     7201 tagagactca tagtgtaatt gcacactatg attataatga taaattaact gtacatacac
     7261 cttgccaaaa tacatttgga tttagaataa tactgtctca aatttttggg atgtcattaa
     7321 ataaagtaag agttataaga cctgctattg gaggttcatt tggaggaaaa ttagaactta
     7381 caattgagcc agtagcagcc gcattatcaa aaatgacaag aagaccagtt aaaatggttc
     7441 ttacaagaaa ggaatctatg atatcaacaa gaactcgtca tgggtccttt gtaaaattaa
     7501 aaactggtgt aaataaagat ggcgaagtaa tagcacaaga tataaaaata tatacaaata
     7561 caggcgcata tgcatcaagt gctttaaatg tcataggagc acttagtcat aaagtattta
     7621 aagtttataa aataccaaat ataaagttta ctggaatgcc tgtatatact aatacaccaa
     7681 tagcaggagc tatgagaggt tatgggtcac ctcaaatatt tatggctcaa caggctcaat
     7741 ttgcgaaaat agccaaggaa ctaggtatgg atttagtcga ttttcaaaat aaaaatgcag
     7801 tagagccaga tgatgtcgat ataatcttcc acggttctct tggaaatcct agagtattgg
     7861 attgtataga gcaaggtaag aggatgttta agtgggatga aaagaaaaaa cttccaaaag
     7921 aagaaggtaa atatttaaga ggtataggta tggcaatagg tgcacatggt aatggagttt
     7981 ttggtgcaca tagagatgtt gttacattga ctcttaaatt aaatgaagat ggtacattga
     8041 cactaataac aggagcacat gatatgggta atggtgttgt aactatgcaa acaatgatgg
     8101 tagctgaaat tttaggaata acacctgata aagttgatac atttgaaact gatacggatg
     8161 catgtacatt caaccttggt gattatgcta gtagaggggt atttgtagaa ggtggaggag
     8221 ctaaaaagac tgcagaaaaa ttgaaagtcc ttatattaga agaagcagaa aaattacttg
     8281 aaacatcaaa agaagattta tatctagaca atggatacgt aattagtaaa cttaatgaaa
     8341 atataaaagc atcactttct gatgtcgcag tatatagtca aagtaaatca ttaagagagt
     8401 taactgttgt tgaagattat tcttcaccaa ctggacttac ttcttatggt gtacattttg
     8461 ctgaagtttt agtagataaa gaaactaaag atataaaagt agttgatttt gtagctgtac
     8521 atgatgttgg tagagttata aatcctctaa atttagaagg tcaattagaa ggcgggattc
     8581 atatgggtct aggatacgca ttgagtgagg agttggcatt tgatgaacaa ggtagaccta
     8641 aagctactga ttttaaaaca tataaattat ttagaactgt agatatgcca aaatgtcaag
     8701 ttgcatttgt gaatagttat gaaaaagctg ggccttttgg tggtaagagt attggagaat
     8761 gtgctgttgt accagttgca ccagctgttg caaatgcagt atataatgca acggatgtag
     8821 aaatacattc attgccaata aaattaaaat agtagaaaaa gcataaataa caatttattg
     8881 tatttgtaaa tagataataa aaatagattt atttggtgag gagatattat tatggcaaag
     8941 atattaggga tttgtggaag tccacgtaaa ggagcaacag aatatgcagt gctagaagct
     9001 ttgaaagaag cagaaactat accaggtata gaaactgagt attggtcagt tagagggaaa
     9061 aaaataagtc cttgtgtaca ttgtgatgca tgtataagaa aagaaactat gtgtattata
     9121 aaagatgata tccaagaatt agagcaaaaa atattggagg cagatggaat tatagtaggt
     9181 tctccagttt atgatatgaa tataactgct caacttacag cagtgtttaa tagacttcgt
     9241 ccaatgtatt tagttcatcc aggaaaactt caaaataagg ttggagcagc tataactact
     9301 ggtggaacta gatacggtgg tcaagaattg acaaaacttc ctataataaa tttcttccta
     9361 atgcatgaaa tgttagtatc tggaggttta ggtggatgct atataggtgg tacaatatgg
     9421 agtaaagatg gaaaagcaaa aggtgcccaa gaggatgaga caggtatgga cacagtaaaa
     9481 agacttggta aaggtgctgc agaggcagtt atggtttcta agtttggtct tgaaaaatgg
     9541 aatgtcgtaa aagaagaatt agatgttaaa aaagatgaaa aatcacctct tagagaccat
     9601 taaatattta ttatattatt aaatatatac aaatagtgat gtaatagatt attgcatcac
     9661 tattttatgt tttaatttag attttataaa ttttatatta aaaaatatag aaacaaagtg
     9721 ttttgagatt tgtttttaaa ttttaaaaat gagaattaaa aagtgagaag atagaaaagg
     9781 ttttttagtt attaaattct atatacattg tatgaactaa agatagaaaa gaaaaaataa
     9841 taaaagcatt gcaatttcta tactaaagag tcatggaaaa atatttagta tatatttagt
     9901 gttggcatgt taattgctta tatattaaag tataaaaatt taacaataat ttggaggtat
     9961 tttagatgtt aaaagaaatt aaatggaaag taaataattt gccaaagggt gataaggaaa
    10021 attgtatcaa atttttaaat gaagaagaaa taactaaggt tagaaacttt cacaaaagct
    10081 ttcctcaata taaagaaact ccattagcaa acctagaagg tttagcaaaa aaattaggtg
    10141 ttgcaggagt atatgtaaaa gatgaatctt atagatttgg attaaacgca tttaaagtat
    10201 taggtggctc ttattctatg ggtaaatatt tagctcaaag attagataca gatatatctg
    10261 agttagggta tgacaaatta acttcagatg aaataaaaga aaagttagga gaaataactt
    10321 tctttacagc tacagatgga aatcatggta gaggagttgc ttggacagct aataaattag
    10381 gtcaaaaatc tgttgtatta atgccaaaag gttcttctga atttagatta aataaaatca
    10441 aaggagaagg tgcagatgct agtataacag acttaaacta tgatgatgca gtaagattag
    10501 ctaatgatta tgcagaagct gatgaccatg gagtaatggt tcaagataca gcatgggacg
    10561 gatatgaaga aataccagca tggataatgc aaggatatgg aactatggct caagaagcta
    10621 tagaacaatt aaaagaatat ggagtagata gaccaacaca cgtatttgtt caagcaggag
    10681 ttggttcact tgctggtgca gttcaagggt atgttgcttc aatatatgat gaatgcccaa
    10741 taacagtagt agtagaggct gatgaggctg attgttacta taaatcagca gaagctggag
    10801 atggaaaacc aagatttgtt ggaggagata tgccaactat aatggcaggg cttgcttgtg
    10861 gagagccaaa tactatagga tttgaagtgt taaaaaatca tgcaacagca tttgtttcag
    10921 caccagattg ggtatctgct aaaggtatga gaacattagg taatccttta aatggtgatg
    10981 aaaaggtaat ttctggagaa tctggagcag ttacaactgg tcttttagta gcagctatgg
    11041 aaagagaaga tttagcagat ttaagaaaag atttaaaatt agatgaaaat tcaagaatac
    11101 ttttaataag cacagaagga gatactgacc ctgacaaata tagaagtata gtttgggatg
    11161 gagaatatcc aagtatataa ggaattacta aaatgcaatt attagatatt ggtttacata
    11221 tttagaagat atataagttc taaattttag aaaatatata gtatataaaa tacatacatt
    11281 ataaaaaatc tagggggata atgaaatgtt aaacgaacaa agaaaacaag aagtaactga
    11341 aatatgccaa aaattaattc aaaatcctag ttcttctgga aatgaagaag gtgttgtaaa
    11401 agcaatagaa gagtcttttg aaaaattagg ttttgatagc tggtcaagag atagatatgg
    11461 aaatatagta ggatgtataa aaggtaacaa gccaggtaag aaaatattat ttgatggaca
    11521 tatagataca gttccagttc cagatgcaag taaatggagt gttcctcctt ttgaaggaaa
    11581 aatagttgat ggaaagatat atggtagagg aacttctgat atgaaaggtc aatatactgc
    11641 aatgatgtct gctgtagctt attttgctaa agatactaat aaagattttg ctggagaact
    11701 atatgtagca ggtgttgttc atgaagaaat attcgaagga gtttcagcta gagagataag
    11761 taaagctgtt caacctgact atgttgtaat aggtgaatct tcagagttaa acttaaagat
    11821 tggtcaaaga ggtagaggag aaatagtagt agagactttt ggtaaaccag ctcactctgc
    11881 taatccagaa aaaggtgtaa atgcagttta taaaatggct aatgtaatcc agaagataca
    11941 acagttagta cctccaactc atccagtttt aggtgatgga atactagttt taacagatat
    12001 aaaatcttct ccatatccag gagcttcagt agtgccagat tattgcaaag ctacttttga
    12061 cagaagatta ttagttggag aaacaagaga aggagtatta gctccaatac aagctttatt
    12121 agatgaaatg atgaaagaag acccagaatt aaatgcaaaa gtttcttatg cagttgaaaa
    12181 agctgactgc tatacaggaa atactataga aagtgaaaga ttcttcccag gttggttata
    12241 tgacgaagaa gatgagtttg ttcaagcagc gtataaggga ctaaaagaag ctggaataga
    12301 ttcagaaata actcaatact cattctgtac aaatggaagt cactatgcag gtgaggctgg
    12361 aataaaaact ataggatttg gtccttctaa ggaaaatctt gctcatacaa tagatgagta
    12421 tatagagcaa gagcaattat ttataggaac agaaggttac tatggaatat taaaatctgt
    12481 atacggaaaa taatgtttag ttcacaataa attatttaaa tatagtctag aggtgctgaa
    12541 tatagcacct ttagaaaata caattttaaa taaaatttta cgatacctag aaaatacttt
    12601 aaagcttaaa agttaggagg tatatatggg aacaatacta agaggtggaa ctataattac
    12661 ctctgataag acttatataa gtgatttaag gatagaagat gaaaatatag ttgaaatagg
    12721 aaataaccta gaaataaatg gtgataaggt tattgatgct acaggtagaa ttgtaattcc
    12781 tggtggaata gacacacata ctcattttga tatgaatgca ggttctatta caactgcaga
    12841 taattttgaa acaggaacaa gggcagctat agctggagga actactacaa tactagattt
    12901 tgcagaagcc aacgaggggg aaaatttact acaaggtgta gaagcatatc ataaaaaagc
    12961 aattggaaat tgttattgtg attatggttt tcatatgaca attacatgtt tagataaaga
    13021 tacatttaaa catatggaaa agcttatttc agatggaata gtatctttta agatgtatat
    13081 ggcatatgag ggcatgaaag tagatgatgg aacaatatac agagttttaa agaaagcaag
    13141 agatttaggc tgtatagttg gatttcattg tgaaaatggg gatttactaa atgtattgat
    13201 agaagaaaat atacaaaatg gtaatctaga gccaaaatat catccactta caagacctaa
    13261 catagttgag aaagaatctg tttcaaggct tgctgatata actaaattat ctaattcaaa
    13321 atcctatgta gtccacttaa gttgtaagga gtcacttaaa actgtaaaaa tggctagaga
    13381 aaaaaatgta gatatgatag tagaaacatg cccacaatac ctattattag aagacaattt
    13441 atataataag gataaatttg agggtgctaa gtatgtaatg tctcctcctt tgagaaaaaa
    13501 agaagacata aattgccttt gggaagggtt agcgagtgga gatattcaaa cagttggcac
    13561 agaccattgt tcatttaatt ttaagggaca aaaagacttg ggaatagatg attttagtaa
    13621 gataccaaat ggagcacctg gtgttgagca taggttagcc cttttatata catatggagt
    13681 cttagagaat agaataagtg caaataaatt tgtggaagtt acttctacga acgccgcaaa
    13741 aatatttgga atgtatccta aaaaaggcga gatagctgta ggaagtgatg cagatatagt
    13801 cattttaaat attaataaag aagaaacaat tagttataaa actcaaaaac aaaatgtaga
    13861 ttatactcca tatgaagggt ttaaaattaa atgtaaagtt gaagatgtat ttttgagagg
    13921 aaatcatgta gtgcaaagtt gtaatgttaa agaacagcca ataggacaat atattaaaag
    13981 aaaaattact aaataatgcg gggggaaata agaatgatgg atatacttat taagaatgcc
    14041 ataatagtaa ctgtaaataa agagagagaa gttatttttg atggggcatt ggtagtaaaa
    14101 gataacaaga ttgctgatat tggaaattct aaagagatag aaagtaaata tacggatgta
    14161 aaaaaaatta tagatgctaa aggtaaagtt ttattcccag gttttataaa tacacatact
    14221 catttattcc aaactttatt aaaaggattg ggcgatgata tggtacttaa agattggcta
    14281 gaaactatga catttccagc agctaactat ttagaaccaa aagatactta tgatgctgca
    14341 atgcttggat gtattgaagg tcttagaagt ggtataacaa caatggttga ctatatgtat
    14401 cctcatagta agccaggtct ttgtgatgga ataatagatg cttataaaga attaggaata
    14461 agaggaatac ttggaagagg atgtatgaat acaggagctc aatttggagt tcatcctgga
    14521 ataatgcaag atgtagaaac ggttgaaaaa gatgtacgaa gattgtttga aaaacaccat
    14581 aatacagaaa atggaagaat taaaatagga gtagctccgg cggcaatatg gtcaaattct
    14641 caagaaatgc ttgagatgct gtggagagta gtaaaagaat atgatgatgc tttatttaca
    14701 gtacatatat cagaaactcc ttttgataga gaagcagcaa aagaattgca tgggcaatat
    14761 gacatagatg ttttagaaaa attaggaata cttggaccaa atgtacttat ggtacattgt
    14821 gtgtatctaa ctgaaagaga tatggaactt gctaaaaaat atgacatgaa agtgtctcat
    14881 aatacagcaa gtaatatgta cttatcttca ggtgttgcac cagtgccaga aatgcttaaa
    14941 aaaggaataa cagttagctt aggtgtagat ggagctgcta gtaataactc tcaagatatg
    15001 cttgaactta tgaagttaac agcacttcaa cataaagtta ataagtgtga cccattagca
    15061 atgtcagcag aaaaagttct tgagttggca actatagatg gagcaagagc tattggaatg
    15121 gaagatgaga taggttcatt ggaaataggt aaaaaagcag acttactaat attcaatcca
    15181 atgctttcac caaaagctat acctatgcat aatccagtat ctacattagt atattcttct
    15241 agcatgaaaa atatagaaag tgttatagta gatggaaata taataatgga agattcgaaa
    15301 atattgacaa ctgatgaaga taaagcatta aaagaggctc aagatacagc tgagagactt
    15361 tgtgtaagag gaactatcaa gaatagaatg gaaggtcata aatggaatag cctttattaa
    15421 taaatgtaat ttattcataa aaaagtatag taaaaacttt aacttaaaaa tatgagtttt
    15481 gaggtgattt atttgattat caaatgtacc ataaataata aagaaaaaga attaagcata
    15541 agaccagatg attttttagc agatacatta agagaaaatg gatatgtaag tgttaaaaaa
    15601 gggtgtgata caggctcatg tggcttatgt acagtgatgg taaatgacaa ggcagtactt
    15661 tcatgtaatt atcttactgc tagagtagat ggtcagcata ttacaacact tgagggtgtc
    15721 ttggatgaag cgaaagaatt tggagatttt cttgcagatg aaggggctga ccaatgcgga
    15781 ttttgtgctc ctggatttat aatgatggtc ttggctatga aaagagagct tcaaaatcca
    15841 acagaagaag aagttataga ttatgtaaat ggtaaccttt gtagatgtac aggatataaa
    15901 ggtcaattaa gagcaataca taaatatttg aacacttaga cttttaagtg aaaattaagt
    15961 tgatatgggg agagagtatg ataactataa aggaatatgt agttccaaaa agtttagatg
    16021 aagcttatga actgctaata tcaagaaaaa ataacataat acttggagga tgtggatttt
    16081 taaaactagg tagtaaaaat attggttcag caatagattt aaaaaactta gctttagatt
    16141 atataaatga aactgatgat agtatattaa ttggagcaga tacaagttta agaactttag
    16201 aattaaataa ggttattaaa aattactgta atggggtaat ttcaaacgct gtttctaata
    16261 tagtaggagt tcaatttaga agtggagcta gagtaggagc tagcgtattt gctaagtatg
    16321 gattttcaga tttaatacct tcattactag tggtagatgc aaaggttaag ttatataaaa
    16381 aaggggttat gagcttagct gattttttag aaagtgagct tgaaaaagat atattaatag
    16441 aagttatatt acctaaaaaa gatgctatag gtgtatttga ttctataaga aaatgtacag
    16501 gtgattttgc agtattaaat ggagcaatgt taaaagaagg aagtatttat aaaattgcaa
    16561 taggtgctag accaagaaga gcaaaaattg cctataaagc aagtgaaata ttaagcttag
    16621 aaaatgatat agaaaaagct ggcgaagtat caagtgaaga actttcattt ggaagtaata
    16681 taagaggaag taaagaatat agaaaagata tggcaaaagc cttagtatta agaatgtata
    16741 atagtattgg aggtgagtgt gatggtaaat aaagaggtaa gaaaaataga tagtgaagca
    16801 attgttactg gaaagccaat atatacagaa gatttaattt ttcataaaga tgttttaaca
    16861 attaagcttc ttagaagtcc acatgcattt gcgaagataa aaaacataga tataaaaaat
    16921 gcgttaaagg taaaaggtgt agtaaacata ttcacttaca aagatgttcc aagttataga
    16981 tattcaatgg ttggggagtc atatccagaa gcatcacctc atgaccaatt aatacttgaa
    17041 gacgtagtta gatatgtagg agatgaagtt gctataatag ccgctgaaga tgaaagggct
    17101 gctattaaag ctatgaaact tataaaagtt gaatatgaag taatgactcc tatattggat
    17161 gcaagagaat cagaaggaaa taaaatttta atccatgaag aagatgattt gttttgtcca
    17221 tttgattttg gattggatgc tacaaaaaat atcgtatcaa gagaaaaaat gggtaaaggg
    17281 gatgtagaaa aagagtttaa agaaagtgat gtaatagtag aacattctta tatgactcaa
    17341 tcacaagccc attgtatgat ggaaactcat agagcttata catatataga tacgaatggc
    17401 agattagtag taacttctgc aaatcaatca gcttatcata tgagaagaca ggtttctaga
    17461 gcattgggga tacctctttc aaaggtaaga gttataaaac caagaatagg tggaggtttt
    17521 ggtggaaaaa acatagctgt aacagagata tatgcatcat ttgtaacttg gatgacgaaa
    17581 agaccagcaa aactaattta tactagagaa gaaacttttg caatgactaa tactagacat
    17641 cagatgtttt ttgatataaa aattggggca gataaagaag gaaacataaa agctatagat
    17701 atgaaagcat tgaacaatac aggtgcttat ggtgataatg gaccttcagt ttgctctgaa
    17761 tcaggtcata atgtacttcc aacatataat aatgtacctg caataaaatt tgatgggaaa
    17821 actgtatata ctaatttagt tccaggggga gcattaagag gatatggagc aacacaaggt
    17881 acatttgcac ttgattgtgc aattgatgaa ttagcgcata aacttaatat ggacccaaca
    17941 gaaataaagt taaagaatat tataaaaaaa caaactgaag gcggaataat gaattttcca
    18001 ataagaagtt gtgcacttga tgaatgtata attagaggta aaaaacttat tggatgggat
    18061 gaaaaatacc ctgttaaaga tattggaaac aataaggtga gggctgttgg aatgtctgtg
    18121 ggaactcatg gttctggtat agccaacata gatatggcaa tagtaaatat gaggatggat
    18181 gaagatggga cttataagtt gttttctggg tcttcagact tagggactgg ttctgacaca
    18241 atacttgcac aaatagctgc aaaagcattg aacacatcta ttgacagaat ttctgtttat
    18301 acaggagata cagatatgtg tccatatgat actggggcat atgcttcttg tactacttat
    18361 gtaactggaa atgctacaat aaaatctgct gaaagtttaa aacgaaagat attaaaagta
    18421 gcacagaaga aacttgattt accaatagat gatttaatac tatatgaaga tagagtttgt
    18481 tatagtgagg atgtagagaa gtttgttttg ttaagtgaat taggaaaaga atctgttggt
    18541 ggtggaaatc aagaagtttt atattcatct gaatcttatg gtatacaaga gagtgctaaa
    18601 ccattcttag caggatttgc tgaaatagag ttagataaaa caacagggga gtttaaagta
    18661 ataaattatg cttgttctac agattgtggt acagttatga atcctgcact tgctagaata
    18721 caagttgaag gtggtgtaac tcaaggtata gggcttgcaa tgtatgaaga ccctagacat
    18781 ggttctgatg gaaagcttca gacttctaat ttattacaat acaaagttcc aacaaaaaaa
    18841 gatataggaa atataattgt tgattttgta gataattatg agccaacagg tccatatgga
    18901 gctaaatctt taggagaaat agttattcat acacctgcac cagcaatagc aaatgcaata
    18961 tacaatgcca caggagttcg tataagagaa cttcctataa cttctgagaa agtttatatg
    19021 gccatgaaaa aattaaatca gggaggtaaa taaatgattg ctattaaaag taaatactta
    19081 atatcttctg ctgatgaaat atatacaaat tatgctgttg tagtagaaaa tgacattata
    19141 aaagatatat tgccaaatga agaagttgaa ataaaataca aaaatattga agaagtaata
    19201 gataaatcag atgctataat aatgccagga tttgtaaatg gccatatgca tcaatatgga
    19261 gttctttcta gaggaatacc ggcaaatgta cattttactg actttgaagg tttcttaaat
    19321 gactattggt ggccatttat agaaaataga attggattga aagaagtaaa ggcaacaact
    19381 aaagcatcag caatagaact tatagaatct ggtgtagtag ctttttgtga taccctagaa
    19441 gctccaaata cagaagaagg aactctaatt gaacaaggaa aaattctaga agagataggc
    19501 atgaaagcgg ttttatcatt agaaagttgt gagagaataa gctttgaaaa tgggcttaga
    19561 tgtttagacg aaaattctaa tttaataaag tggagtagag aaaatagtaa attaataaat
    19621 ggaataatgt gtacacatac aagctttaca tgttcggata aatttattaa gaaagctaaa
    19681 gaagatgcaa agaaattaaa tgcaccgatg caatttcatt tatgcgagag tatatatgaa
    19741 ccaaactatg ctgaaaaaca ttttggcaaa aaagcagttg actactataa tgatttagat
    19801 atattggatg aaactgtatt agcatctcag tgtgtaaaag taaatgatga agaaatagat
    19861 atattaaaag aaaaaggcgt aaaagtagtt catatgcctc ttagcaactg tgaagtaggt
    19921 ggaggttttt ctccagtacc aaaaatgatt aaaaaaggca taaaagtggc actgggtact
    19981 gacggatata taaatgattt ttttgaagtt atgagaggtg catttttaat gcataaatca
    20041 gttgaagaag atgcatcagt aatgccagca aatttagtat ttagaatggc aacagagcat
    20101 ggtgctcatg tattaggact tcaaaattct ggtaaaatag cagttggtaa taaggctgat
    20161 ataatagtta tggaagatga atttaaaact cctgtgactc ttgataatat atttgaccag
    20221 atagtagttc agggtaaaaa agaatttata tcaaatgtat acatagatgg tagacatatt
    20281 ttaaaagaaa aacagctagt tgatttagat aaaaaagcta ttgttaaaga aatgaaagaa
    20341 gttgcttgtg aattttggaa tttttaacga atgtaaatat atatgaaaag gggaagcaga
    20401 taatgtacaa ttttttaggt aaagaattaa aatcaccact tataataggt tcagggccat
    20461 taacatatag tgcggctgga tgcaagatat taagtgatgc aggagcaggg gcagttgtta
    20521 ctaagactat aagaaaagaa agagctataa atccagcacc acatatggtt agaaatacag
    20581 ctaatgctct tttaaataat gagaaatgga cagattttga gccagagcaa tggatagatt
    20641 ttgaaatacc acaaatgaaa agagatggga ctgtatgtat agcttcagta ggtcatacaa
    20701 ttgaagaaag cagcgaatta gtagaaaaag ttgcaaatgc aggagcagac tttattgaat
    20761 tagtatctta tgattataga gatttgatac caatgcttaa agatgcaaag gaaagagtaa
    20821 atataccagt aatagttaaa cttcctccta tgatagatga gataggcgat tttgccaaaa
    20881 aattagaaga agcaggagca gatgcaataa ctgcttgtga ttctgtagga ccagcattta
    20941 gaatagacat agaaacaggg caacctttat tagggggaaa tggaatagga tatttaagtg
    21001 gagaaactat caagccaata actttacaga gaatatatga aataaaaaaa caagttaata
    21061 taccaataat tggtctaggt ggatgtgtaa gtggagatga tgccttagaa atgattatgg
    21121 caggtgctga ctttgttggt atatgttcag tagtaatctt aaaaggtgca caagtaatat
    21181 ctaaaataca tgatgactta aaatctaatc ttaatagatt aggatataat actatagaaa
    21241 atgcttgtgg aatagtacat aatcatatgg gagatgttaa tgaaagactt agctttgagt
    21301 ttacttatga tgaagaaaaa tgtactaaat gtaagatgtg tgagagagtc tgtgcatatc
    21361 aagcgagaaa attgaatgat aaaatggaat tgaatgaaga agagtgtaga tattgtggac
    21421 tttgtatatc agtttgtaaa ccaaaagcac ttggaagaaa aatttcatgt tcagagttga
    21481 atgtatagat tattttataa aaaataaagt tttaaataaa aataagaagg cctatctcaa
    21541 aatagagata agcctttttt gttgacctta tttttgttta tttatagtta ttttagatat
    21601 taattagttt tgaagtaata aagtgcgtaa attttgttta attaaaattt taataattct
    21661 tatatatatg ttaacattgt atagcatttg tgtaaaatgt tataataatt aatagggatg
    21721 gtgatgcaag tgcaagagaa gattttagaa ttattgtata ctataaatga agatgtagtt
    21781 agcataaaaa atgatatgtc agaagtaaaa caggaaataa atgtgttaaa agaagatatg
    21841 tcagaagtaa gacaagaaat gactgtaatg aaagaagata tgtcagaagt aaagcaagaa
    21901 ataaatataa tgaaagaaga tgtgtcagaa gtaagacaag aaataaatat attaaaagaa
    21961 gatatgttag aagtaaaaca agagataaat ataatgaaag aagatatgtc agaagtaaaa
    22021 caagagataa atataatgaa agaagatatg tcagaagtaa gacaagaaat gactgtaatg
    22081 aaagaagata tatcagaggt aaaacaagag ataaatgtat taaaagaaga tatgtcagag
    22141 gtaagacaag aaatgactgc aatgaaagaa gatatgtcag aggtaaaaca agagataaat
    22201 gtattaaaag aagatatgtc agaggtaaga caagaaatgg ctgtaatgaa agaagatatg
    22261 tcagaggtaa aacaagagat aaatgtatta aaagaagata tgtcagaagt aagacaagaa
    22321 atgactgtaa tgaaagaaga tatgtcagag gtaaaactag aagtaactgt aatgaaagaa
    22381 gatgtttccg aagttaaatc agaagtaaac tttatgcaaa ataaaataaa taatattaat
    22441 aaagatatga gtggaattaa ggaagaagta tccatagcaa atgaaaaatt agatggaatt
    22501 gaaattaaga ttgatagtct agaaagtgaa gataagtcaa tgaaagagat gcaggtagaa
    22561 cagaataata ttttaggaag cttattacat aattctgaaa taaataaagc tactcatgat
    22621 aatatagaac ataacatagc atatataaaa ggagatacta attctataaa agaggatata
    22681 gctgaaataa gaagagactt aaatttagta gagttagcca ctagtaaaaa ttggagtgat
    22741 attgtcaaac taaaatcagt aaagtagtat tttaattcac taatttatca tccacaaaca
    22801 taaaagaatt tatagtgttc ttactattta ttataaattt tagaaatgaa aataaaaaat
    22861 tgagaaaaga ccgttaaaaa tttattttta ggtctttttt ttatgcaaat ataactgatt
    22921 tataaaaata aaacctaaaa tttaaatgat aaaatctaat agaacgattg aaataagtaa
    22981 aattttatca ataaaaacat aaaaatttta tactatgtga atgaatgcaa atattggcac
    23041 taaaattgct ctataaaaat tataaatagt aatatgaata aaattttttc tataagaaca
    23101 atattactat tttacttata gatatatata tatctataaa tagatagaaa cttgtatatt
    23161 ttatgttgca gatacaaata tagtaaagga gagtacattg gtacaactga gatacatagc
    23221 ttattaagtt tttctgtctt atgagaatta tattataaaa tattcataaa tattttgagt
    23281 ttaaattaaa aaattatttt atgcttagat taattgctat ttaattaatt taataacaaa
    23341 aacagtgaaa gagtaaatag tattatttac agggggtaaa gcaaagtata ttaaataaat
    23401 tgtactttta gccccgtaca tagagaaatc tatgtaggac acaactttaa aaccagtaaa
    23461 tcctaaagcc ttacaactac aataaaagat agaaagaaac ttttatgaat gtggtgaaaa
    23521 ccagaaataa tagtgaggat ggtatatggt gagagcctaa gtacttaaaa atggacattt
    23581 ggtcgccaag cctagaaata ggaaggtcaa acgactatct cgagagagag tacactataa
    23641 gtgattgata gtggaaacgg gttgctctta gcaggtaatg ctgaagatga agaaatagtc
    23701 tacgctcata tgaaagtatg aggtcactgg atttgaagtg acatctataa agtagcgttt
    23761 ataggtaaat gtttaaaact tgaaaaatat aaatacttat gaaaacttat aacttataat
    23821 gattaagatt gaaagattta aattgaatta aatttactat aaaaaattaa aaattcatag
    23881 ctataatact cttatatttg taaagcatta tatataatat atgcaaaatt aaagaataag
    23941 tttatttgtt aataattaaa tttattgtat ccttttttag accaaaaact taaatatgtg
    24001 ttggagtata gttgcgattt atgaacatca ttaatttaat atattagatt tttaagtatt
    24061 tatataattc aataagtttt atgtaacggg agtttttatt atgaaagcaa aaagtacatc
    24121 aaaatttgaa ttagacggaa tgccaccact aaaggaagca atacctttag ggttacaaca
    24181 cttaatggca atggtaatag gtagttgttt accagcgata ttgattgcaa atgcagctgg
    24241 acttaatcat aagatgtcaa cattattgat tcaagccgca ttaatttttg caggattatc
    24301 aactttatta caattatatc caataccttt gtttaaaggt tttaaattag gaggaggaat
    24361 accagttata atgggagcta cagctatgtt tataggagct ggggtatctg ttgcaggtaa
    24421 gtatggacta ccagttttat ttggttctca aataatagct ggtatagtaa taattataat
    24481 tggttttggt cttaaaaaaa tacgatttat atttactcca gctgtatctg gaacaatagt
    24541 tgcatgtatg ggtcttgggc tttttccaat agctataaaa aacttagctg gaggtatggg
    24601 aaatgaaact tttgggaatc aaattaattt tatagttgga atatctgtat ctcttatgat
    24661 attaggatta aacaagtatg gaaaaggatt atttaaagat gcatcaatat tagttagcat
    24721 aatctttgga tacattttat cattaatttt aggaatagta aatttttctt caattcaaga
    24781 gtttactttg gttgcacttc caaaaccgct tatttttggt ctagatataa gacttgaagt
    24841 tgttgtaatg ttttcaataa tatatttagt tgagatagct gatataatgg gtgcctgcac
    24901 actttctgcg gtaggagggc ttaatagaca agtaacagat gaagaacttt cttctgctgt
    24961 tttaggaaat ggagtactct ctacaatagg tgcattattt tctgcaactc caatggggat
    25021 gtttggacaa aattctgcaa tcgtttccaa tacaaagatt gtaagtaaat tcgtactagc
    25081 tattggagga attggactat ttttggcggg aatatcgcct ttattagcta atttaataag
    25141 aacaattcct ccttgtgtgg ttggaggggc aacacttgtt atattttcaa ctcttacaac
    25201 atctggttta cgacttgtta gtatggatgg atttaatcaa gaaaatagca tgatattagg
    25261 tctttctatg gcttctggta ttgggttcat ggtagctcct caagttcttg aaagatttcc
    25321 aaagtttgta gaaacattac ttgcagattc aagtgtagtt tcaggagcta tggtagccat
    25381 aataatccaa gctttatata tggtaaaatt tcctaaaaat aaaaatggta aagttgagga
    25441 taaaaataaa agtttataat gtaaagattt tatacatgtg aattaaatat actacaatta
    25501 taaatataaa taaaaagatt tattaaaact cttatgtttt aataagctaa tgatgggggg
    25561 ataagatggt tactataaag gaatattcag ttccacagag tttagaagaa gcatataaaa
    25621 ttttaacttc taaaaaaaat aatgttattt taggtggatg tggattcata aaattaagca
    25681 ataaaaatat aggaacagcg atagatttaa aagatataaa tctaaattat ataaaagagg
    25741 atgaaaaaaa tattttgata ggtgcagata cttctcttag aagtttagaa atggataaaa
    25801 ctataaaaaa ttattgtagt ggaatacttt caagtgctgt ttctaacata gttggtgttc
    25861 aatttagaca aggagctaga attggtgcaa gtgtattttc aaagtatggt ttttctgatt
    25921 taataccagc acttttggtt gtcggggcaa aggtaagatt atacaataaa ggaatgctgg
    25981 agttgaatga gtttttggat agtgaattaa gtagggatat attggtcgaa gtaatactac
    26041 cgaaaaaaga tgcgatagct gtttttgact caataagaaa gtgcacagga gatttttcta
    26101 tattaaattc agcaatgtta aaagaaaata atacttacaa aatagcaatt ggggcaagac
    26161 ctcaaaaagc tagattagca cttgaagcaa gtaatatatt aaataaagaa aaagatatag
    26221 ataaggcatc tattgttgct agtaaggaac ttacttatgg aagtaatatg agagctagca
    26281 aagagtacag aaaggatatg gcaagtgcat tagttaaaag gatgtataat gctattgagg
    26341 agggaatgta taatgattaa taaggggata agaaagatag atagtacagc aattgtcaca
    26401 ggaaaacctc tatatactga agacctcatt atgcataaag atgttttaac attaaagtta
    26461 cttagaagtc cacatgccca tgctaagata aagaatatag atacatcaaa agctgaaaaa
    26521 attccaggag ttgtgggtat ttatacgtat aaagatgtac cacaggtcag atactgtgtt
    26581 ccaggccaaa cagagccaga agcatcacct tatgatagag ttttacttga agatagagtt
    26641 agatttgttg gagatgaagt agctttagtg gccgctgaag atgagaaaat agcactcaaa
    26701 gccttaaaaa tgataaaggt agactatgag gttttaaaac ctgtgtttga tgcaagagaa
    26761 gcagaaggaa atgaagttgt tatacatcca gaaaaagaca tagtagagcc ataccctttt
    26821 ggattggatg caaacaataa tatagtatca aaagaatttt ttgaatttgg agatgttgag
    26881 gctaagctta aagaaagtga tcttgtggtt gaatcttcat ataaaactca aagtcaatca
    26941 cattgtatga tggaaactca taggtcatat tcatataaag atataaatga tagaattgtt
    27001 gtagtttcat cattacaatc accacacaat gtaaagagaa tccttagaaa agtattgggt
    27061 ataccatctt caaaaataag agtaattaaa cctagaatag gtggtggatt tggaggaaag
    27121 aatatagcag ctacagatat atttactgcg tttgttacca tgaaaactgg tagaccagca
    27181 aaatttgtat ttacaagaag tgaaactttt gtaggttcta atagtagaca tgaaatgttt
    27241 tttgatgtta aagtcggtgc agataaagaa ggaaatttaa aggcaataga attaaaatca
    27301 ttaaacaata caggtgctta tggtgggaat ggtgtctctg tttcttctga atctggacac
    27361 aataccttac caatatataa tgatattgat gctgttagat tcaatgctag aacagtatat
    27421 actaataggt taccagcagg agcacttaga ggatatggtg ctacacaggg aatatttgca
    27481 ttagatagtg ctattgacga attggcacat aagattggaa tggacccact tgaatttaga
    27541 attaaaaata taatagatag gtatactagt ggaaaagcag ctgaaggtga aatattaagt
    27601 tgtgagttga aacaatgtat agaaaagggg aagaaattaa ttaattggga tgataaatat
    27661 ccatgtaaag atataggaaa taacaaagta agagcagtag gtatggcagt agcaaatcat
    27721 ggttctggta taccacgtgt agatatggca acagtgacta taagaatgga tgaagatggc
    27781 acatacaaat tattatctgg tcttgctgac ttaggtcaag gagctgatac aattcaagca
    27841 caaattgctg ctgaagcttt aaatactact gtagatagaa tttctattta tacaggtgat
    27901 tcagatttat gtccatatga tacaggagca ttcgcttctt gtacgacaac ggttacagga
    27961 aatgcaacaa taaagacagc aaataaatta aaagatatat tactttcagt tgcggagtca
    28021 aagctaggat ttaaaaaaga agatttagag ttgggaaaag acagggtttt tgttaaaaac
    28081 gataatagta agtttgtttt attggaggaa ttgggtagag aatctgttgg aggaattggg
    28141 tttgctagtg atgatgtacc agtagttttg gaagcaacag aatcttttgg tatattaaaa
    28201 aaaataaaac catttatagc aggatttgca gagatagaat tagataaaaa tacaggcgaa
    28261 tataaggtaa taaattttgc atgtgtacct gattgtggaa cagttataaa tccaactttg
    28321 gctagaatac aagtagaagg cggtgtgatg atgggtatag ggtttgcaat gtatgaagac
    28381 cctagatttg ataaagatgg gagattatta acaaatagtt tcctacagta taaagttcct
    28441 acaaaaaaag aagttggaaa tatattggta gattttgctg agaatttcga ctcaggaggt
    28501 ccttacggtg ctaaatcatt aggagaaata gttatacata caccagcacc agctatagca
    28561 aatgcaatat ttaatgctac aggagttcgt ataagagagc ttcctatgac ttttgaaaaa
    28621 gtttatatgg gtatgaaaaa taataataaa caattataat aagtaatatg ttgtataaaa
    28681 acttgtaaat ttaaattatt ttgtaaaata aagtaattaa atggacatta tatatggtgt
    28741 tttataaaaa taccgtatat aatgtctagt agagtatatt ctaaaggagg tgagttaatg
    28801 tcaaacagaa taaaaaatat acactatgga acccagagac aacaattaaa aaacttaact
    28861 aaaaaagaat atcaagctct acgagagatg tgcttcttag ccaagaactt atataatgtt
    28921 ggtacatata atgtgagaca acattatttt aatcaaggag aacatcttaa ctatgaagct
    28981 aattaccatg tatgtaaaga aaatgagaat tataagcttc tcaatagtaa tatagcgcaa
    29041 caaatattaa aagaagtcga cagttcattt aggtcgtttt ttggattaat taaattagcc
    29101 aaagaaggta aatatgattt tagagggata aagtcaccta aatatttaga taaagaagga
    29161 ttttttagta taataatagg tcaaataaga atcaaagaag atgggactct aaatgtacct
    29221 atgtctccag tatttaaaaa actatatgga aaagtaagta taaaagttcc tcaaaatata
    29281 ctagagaaaa aaattaaaga aataagaata atacctaaac ataaagctag gttctttgaa
    29341 attcagtatt gttatgaaat accgaaatca gaggaagttt caaatcaaaa aaatgcacta
    29401 gctatagatt taggtttaga aaatttatgt acatgtgtta ccaatttagg tgatagtttt
    29461 atcatagatg gcaaaaggct taaatctgtg aatcagtggg caaacaaaca gaatgataaa
    29521 atagaggcct taaaattaaa aaagaatata actgcaataa caagaaaaca atttaaagtt
    29581 tggaataaga gaaataatca agtcaaagac tatgtaaata aaacttgttt ttacataatt
    29641 gattactgta taaaaaataa tattggtaat ttaattgtag gatataatgc taagttagaa
    29701 aaaagtgata atatggagag aaaaatatat agaaatttta taagaatccc ttttggagag
    29761 ataaaaggaa aattagaata tctatgtaaa ataaaaaata tcaattttat taggcaagaa
    29821 gaaagctata ctagtaaatc tgattttttt gccaatgatt ttctacctga tatcaatgtg
    29881 gacaatgtga aaaaatatga ctttaaaggg gaaagaataa cacgtggaca gtataaatcc
    29941 agtgttggaa tcattataaa tgcagatgta aatgcgagtc ttaatatatt aaaaaaatca
    30001 caagtagtta atttatctaa tttgcagaat aatcctcaaa tattaaagca accacagaga
    30061 gtaagaatat cataattata tttaaaagat aaactgatag cgtaagctta cagcttagcg
    30121 gcgaattgga tccgccttgt tgtttacaac agaatctatt tactttcgag tttatggaat
    30181 ttcaaaaatc acttttacta aaaaggtcta gctgtaaaaa ttaatagatt agaaaactgg
    30241 ttataagagg tgaaagtgtg aaactatcaa atataataga aaagaatgaa ataataactg
    30301 tagttggagc aggaggaaaa acttcattta taaactattt tgcaaatttt tatagagata
    30361 aattgaaagt tctacttaca acaacaacta aaatatatgt accaaatgat tatgacaata
    30421 taattactac aatagatgga actattattc catctatttg tcatggaata atagtatgtg
    30481 gtagtcatat aaataatgaa aataaattag taagtattga ttcatctatt ttggatgaaa
    30541 ttgtagacaa atttgattta gttttaatag aaggagatgg ttcaaagaga aaaaaactta
    30601 aaggttggaa tactaaagaa ccagtagtat atcataaaac tacaaaaact ataggtatat
    30661 tagatataac atcatttgga atggatatta atgaagaaaa tatacacaga gtagaaatgt
    30721 tcaaaaaaat agcaaattta aatacaaaga gtattaatag tagctctaca gtaagtattg
    30781 aaaacttaaa aaatatagta ttaaatccaa atggattatt taaaaattat tctggaaaaa
    30841 gagtattatt tattaataaa gttgaaaatg aaaaatataa aaatttagct ataaaattaa
    30901 taaaaaatat taaagaatgt gaaagtgaaa tagagatatt ttatggaagt gtaaaacaaa
    30961 aattttgtgc aagatattga agtattaaaa tagtttatat gatattatat atatagataa
    31021 tatcaataga gatattataa aaatcataga actatcaata tattataaat atactataaa
    31081 taccaaggat gatatatatg ataaatgcag tgataatggc atccggtttt gccagaagaa
    31141 tgggagtaaa taaactttta ttagattata aaggatgttc tataatagaa catgtattta
    31201 gagtagtcaa taagattgat tttcatcaag ttgtagtagt aagtcaatat gaagaagttt
    31261 tattattgtg taataaatat ggttttgaat atatagataa taaaaatgca aatgtaggtc
    31321 aaagtgaatc tataaaattg ggagttttaa atagctcaaa atgtgatggt tatatgttct
    31381 ttgtaggaga ccagccattt attgataact tatatataga taaaattata aatactttta
    31441 aattagatag agattttata gtaattccaa gatacaaaga tatatgtgga aatccagtta
    31501 tattcccata tggtaagaaa gaagaattgt tagcacttaa agaagatgaa aagggtaaaa
    31561 ctattttaaa aaattcatca aaaataaagt atgtagaagt tcctaaagaa atgttatttg
    31621 atatcgatac aaaaatagac tatgaaagaa ttgggggtaa attatgaaac taataaaaac
    31681 tatagatgct gttggacaag ttttatgtca cgacataact caaataatac ctggcgaatt
    31741 taaaggaaga aaatttaaaa agggtcatat agtaaaagaa gaagatattc cagtgttatt
    31801 atctcttggt aaagataatt tgtatgtatg ggaaaagtca gaaggaatgg ttcatgaaaa
    31861 tgaaggtgca ttgtttttaa aagaactaac tgctggagaa aatttagatt ttagtgaaat
    31921 aaaagaagga aaaatagatt ttatagcagc atgtgatggt cttttaaaga tagatgttga
    31981 tgcacttttt gatttgaatt gtgttggaga aataatgatg gctactcttc ataataattt
    32041 tatagtaaat aaaggtttaa aagtggctgg aacaagagtg atacctttgg ttatagatga
    32101 gaaaaaatta gaagatgcaa aaaaagtagt tggtaataga aaaatagtaa atgtagtgcc
    32161 ttttaaacct aagaaagtag gaattgttac tacaggaaat gaagtatttt atagcagaat
    32221 tgttgataaa tttggaccag taatagaaga aaaagtaaag ggttttggtt gtgaagttat
    32281 aggacagact atatgcccag atgataaaga cgttataaag aatgcaataa aagaatttat
    32341 aagtcaagga gcagaactta tatgctgtac tggtgggatg agtgtagacc cagatgatgt
    32401 tacaccaaca gctataaaag aaactggagc tgatttagtg acatatggtt caccaatatt
    32461 accaggagct atgtttttac ttgcttatta tggcgaagtt ccaattatgg gtataccagg
    32521 atgtgcaatg tatcacaaaa ctacagtatt tgatatagtt ttatctagag ttttaattga
    32581 tgaaaaactt gataagtatg atatagctag atatggccat ggtggtcttt gtatgaactg
    32641 tgatgtgtgt acttatcctg catgtaattt tgctaaaata taaagctatt aaaaaagagt
    32701 atttacaaat taagtactct ttttaaatat gaaacaaaac aactagaatg atgttttaag
    32761 aaaagcatat ttatttaaaa gttataataa ctgattttca atgtgtaaaa gaatgaataa
    32821 agttgcaatt tgatttcttt ataagtataa tataagagat tgttaatttt cataaattta
    32881 caatttttag tattgtttta ataaatattt cacaaatttg gtataaaaaa tatactattt
    32941 acgtgataat agataataaa aatgttatca aagttttatg ataaaataaa ttatgagtaa
    33001 aaagaaagga aaatatatta atgttacaag ttacaggtgt tggacttaga tttggtgata
    33061 aggaactatt taaagatgtc aacttaaaat tcactaaagg taattgctat ggaataatag
    33121 gagctaatgg tgcgggaaaa tctacttttt taaaaatatt atcaggagaa atagagccaa
    33181 atacaggtag tatatctata actgataaag aaagaatgtc agttttaaaa caggaccact
    33241 ttgaatatga agaagaaact gttttaaatg ttgttataag aggtcatgag agactttgga
    33301 atataatgaa agaaaaagat gcattgtata tgaaggaaga ctttaatgaa gaagatggta
    33361 taaaagctgc tgaactcgaa ggtgagtttg cagaacttga cggatgggat gcagaaacta
    33421 atgctgagaa aatacttatg ggtcttggca taactaaaga tatgcattac aaacaaatga
    33481 aagagttagt tggtggggaa aaggttaagg tattgttagc acagtcgctt tttggtaagc
    33541 ctgaaatact attaatggac gaacctacaa accacttgga ttttaaatca ataaactggt
    33601 taaataattt tataatggat ttagaagagt ctatagttat aatagtatca catgatagac
    33661 atttcctaaa tcaaatatgt actaatatag ttgatgtaga ctttggtaaa atacaaatgt
    33721 atgttggaaa ctatgatttc tggtatgagt caagtcaatt agctttacaa cttgctaagg
    33781 accaaaataa aaagactgaa gaaaagatag ctcaattaaa ggaatttata gctagattta
    33841 gttctaacgc ttcaaaggct aagcaagcta catcaagaaa gaaacagtta gagaaattag
    33901 aagttgaaga tatacaacca tctagaagaa gatatccata tgtaggattt acacctgcaa
    33961 gagaaattgg gaatgaagtt ttagaagtac acaatttaac taaaactata gatggggtta
    34021 aggttcttga taatgtgtca tttagattgg atagagatga taaagtagta tttatgggtg
    34081 atgaaatagc tactactgca ctttttaaca tagttatggg agaacttgaa ccagacagtg
    34141 gagaatacaa atggggagta actacttctc aagactatct tccaaagaat cataataagt
    34201 tttttgacgg agtagaatat tctttggttg attggcttag acagttctct gaagaaaaaa
    34261 gtgaaagctt tataagaggg tttttaggta gaatgttatt ctctggtgaa gaagcattaa
    34321 aagaagctca agttatatct ggaggagaaa aggttagatg tatgcttagt aagctaatgc
    34381 tttcaaatgc aaatgtactt gtattagatg accctactaa ccatttagac ctagaaagta
    34441 taacttctgt aaataaagga cttgaaaagt tcccaggagt acttttattc acttctcatg
    34501 accatgagtt tatatctact atagcaaata gaattataga gataactcca aatggaataa
    34561 tggatagaaa aatggatttt gatgagtatt tagaaaataa agagatacaa gaacaattag
    34621 ctaaaatgta tggaaaagat aaataattat tagtataaaa ccttttaata tttgagacat
    34681 gctatgcata agtatgtaag tttttaatca aatattagga ggttttttta tgttatttaa
    34741 atatgtttat tagtagaata atattttgta gactaaaaat ttaaatataa tatagtagat
    34801 gctataataa aaatatagaa tattttaggg ggagtagatt atggttaaga aaaggttagt
    34861 agctatagta atgagtttag ctatgattag tgtaggaaat ttttcatatg ctcactcagg
    34921 agggcataat tcatcaggga gtcatcataa taaaaataaa tcagagttaa catattatta
    34981 ttattgtgga ggacattcag cacatcaaca caataaaggt ttttgtcctt atgctagtgc
    35041 aaaatcaaat tctggagtaa caatatcttc agcacataac gaaaaaaatc ataaaaaatt
    35101 tttttcagaa aaagagtata ataaaggtta tgaagatgga tgtaaagggc tttataattt
    35161 aagtttcaca gaagctaaat ctgaagattc atatgaaaaa ggatatttaa ttggatacaa
    35221 tgaatataaa gcaaaaaaag tatatgatgt aattaagaag atgttagata ttccaatgtt
    35281 agcaagtata taataaaata gtattttaaa agatattttc tataaggaaa tatctttttt
    35341 attgtaaagt acaatcttta ataaaaaagt ataataactt aggtgataaa ttaaaataaa
    35401 acagattatt taagcagtta ttaatttgag atagatacat ttaatatgaa tgaatctatc
    35461 tcaataagct aagctaagtt gatttaatat taattagcat taaataaact ttcagaaatt
    35521 ttgtcagaag cttctttatc catttcttta agtacatgag aataaacgct tagagtagta
    35581 cttatatttg agtgtcctac tctctcggat ataaccttta taggtacttt agaatttata
    35641 agtaaagtaa catgtgagtg tcttaaatca tggaatctaa tatgaggtaa ttcattcttt
    35701 tctaaaaatc ttttaaattt tttacttata acatcttcag caataggttc acatttctta
    35761 ttaaaaaaca acaaattatt attatttcta atggaagatt ttaataaatt tttattctgt
    35821 tttattttat attcttttaa taaagacatt aattctttgg gagaagatat tttcctgata
    35881 gagctttctg tctttggttc tttaagaata acagaaccat taattcggga cgttatctta
    35941 tttactgtta ttgtattttc ttcaaaatca atattatccc aagttagacc taaaacttct
    36001 gaaattctaa gacctaatcc aatagccaaa ttaataggta attccatttc tgtgtttttt
    36061 gctaaatcta ataattttat catttgttcc ctatcataaa tctcattttt aaacttttta
    36121 tatcttggag cctctatacc atccataaca ttttctttta ttaatttgag tctataggct
    36181 ctttttattg caagtttcaa tatatttata tgaatcttaa ttgattgagg atttagttta
    36241 taagagagtt tatctatata gttttgtatg tgaataggat gtaagtcttg tattttatat
    36301 tttccaatag atggattaat gtaattctta caaatactaa cgtaattgtt gtatgtagct
    36361 aaagatatat tttcgctata tttatttaga aaatctaata gaaattctga cactgtaatc
    36421 tcgtttggca ctaaaaaacc gtccttatat aagctttctt ttacctcatt tagtcttttg
    36481 cttgcttccc tttttttatc aaaaataccc atattttttt gttttctttt acctgtctct
    36541 ttatcttcaa attccaggta aacaacatag tttttatttc tttttctaat aaatgcattc
    36601 atatataacc caccaatcaa aattttatac atttattata acatatatat atcccaaaat
    36661 gattttgaaa tagagttgca tacattttaa tacattgtat atat
//
LOCUS       DAMKOJ010000040        36254 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000040 DAMKOJ010000000
VERSION     DAMKOJ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36254
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.042"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            73..1185
                     /locus_tag="PC592_002035"
     CDS             73..1185
                     /locus_tag="PC592_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HDF4056008.1"
                     /translation="MNSRVKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLNTVRILGVLQRMGLVYFVTSLVYLLLKKLNVRSSVTIITFLCISAFIIVGYYIVAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPDFEPDGFLTSIVAISSGMLGCMMGCVLLKENI
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNLPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLVFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1440..3464
                     /locus_tag="PC592_002036"
     CDS             1440..3464
                     /locus_tag="PC592_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4056009.1"
                     /translation="MKKTTKLLATGMVSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGPTRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNITRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQN
                     TYDWLSSQGLEEAYYIGGSQSLSSKIIDKISKIAKNGTSKNRISGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVISSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIFYKVKDKNGGTTKTAASNILKRILEKFNMQNRGIKTRTLANGNDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTTEKVKTMGTQIGIGIEDTVK"
     gene            3684..4370
                     /locus_tag="PC592_002037"
     CDS             3684..4370
                     /locus_tag="PC592_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDF4056010.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4465..5520
                     /locus_tag="PC592_002038"
     CDS             4465..5520
                     /locus_tag="PC592_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HDF4056011.1"
                     /translation="MIKKISTILSLVLLISISSTMWVFADAKPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEDSIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTAKLDFGSRSDVNEYISLGVV
                     SAKENMPILICNDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5636..7192
                     /gene="murJ"
                     /locus_tag="PC592_002039"
     CDS             5636..7192
                     /gene="murJ"
                     /locus_tag="PC592_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF4056012.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVVTLLIYNNLYAFIGSGTIKEIISVGAGVLGGASVYTILIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7238..8944
                     /locus_tag="PC592_002040"
     CDS             7238..8944
                     /locus_tag="PC592_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF4056013.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKDLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIIKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDVANDIIAEVNKIDDYSVIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRRVLSECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKSNGTDLIIGTDPDCDRVGIVVKDSSGEYIVLNGNQVGSL
                     LVRYIVESLVKENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEKSNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALLD
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKEGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8966..10039
                     /locus_tag="PC592_002041"
     CDS             8966..10039
                     /locus_tag="PC592_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HDF4056014.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDRNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKEEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEEISKYLGTKEEVEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10051..10773
                     /locus_tag="PC592_002042"
     CDS             10051..10773
                     /locus_tag="PC592_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF4056015.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIRVLYEQGGVYMDTDMQILKDITPLLEDNR
                     LICGYEDDGEYMNAAILGVEKGHPFFKDLLEYYEKEILTSSLFTIPKIMTHLMEKNYK
                     KIDQNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTYGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10789..11946
                     /locus_tag="PC592_002043"
     CDS             10789..11946
                     /locus_tag="PC592_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HDF4056016.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWNVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11949..12788
                     /locus_tag="PC592_002044"
     CDS             11949..12788
                     /locus_tag="PC592_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4056017.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDANKIDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGDDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFVKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12803..13978
                     /locus_tag="PC592_002045"
     CDS             12803..13978
                     /locus_tag="PC592_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDF4056018.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHRFKGRNIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            14007..14756
                     /locus_tag="PC592_002046"
     CDS             14007..14756
                     /locus_tag="PC592_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4056019.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14778..15686
                     /locus_tag="PC592_002047"
     CDS             14778..15686
                     /locus_tag="PC592_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4056020.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALKGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15734..16486
                     /locus_tag="PC592_002048"
     CDS             15734..16486
                     /locus_tag="PC592_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4056021.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENIGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16464..17807
                     /locus_tag="PC592_002049"
     CDS             16464..17807
                     /locus_tag="PC592_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HDF4056022.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNDVK
                     VELASNPEFLSQGTAVKDTLHASRIVIGVESEWARDILQQIYEPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     EAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKVKDMEELGIEYYSIGR"
     gene            17813..18904
                     /locus_tag="PC592_002050"
     CDS             17813..18904
                     /locus_tag="PC592_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF4056023.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSVKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLTKELGIEDDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLSMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18987..20900
                     /locus_tag="PC592_002051"
     CDS             18987..20900
                     /locus_tag="PC592_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF4056024.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNVFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFMATLAYLI
                     PVYIINKLLGFDYPIIFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKISNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSNIKEVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVDIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21088..21795
                     /locus_tag="PC592_002052"
     CDS             21088..21795
                     /locus_tag="PC592_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF4056025.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAELTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKTVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGNSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22096..24207
                     /locus_tag="PC592_002053"
     CDS             22096..24207
                     /locus_tag="PC592_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HDF4056026.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANNPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGNGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVSWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSSSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWPTNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNSSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKNNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTNL
                     VYTAGDGINQNTLNAFLNLVN"
     gene            complement(24405..25370)
                     /locus_tag="PC592_002054"
     CDS             complement(24405..25370)
                     /locus_tag="PC592_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF4056027.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTIEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNAGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25655..26611)
                     /locus_tag="PC592_002055"
     CDS             complement(25655..26611)
                     /locus_tag="PC592_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF4056028.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPSLVNTILPYVKTNMNPNEIISLGKELLSIGNLDLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26980..27768
                     /locus_tag="PC592_002056"
     CDS             26980..27768
                     /locus_tag="PC592_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF4056029.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEAIKDDMMFISENGTLVVYKGKEILSNPLDKELVNEIIETTRSIEGKKI
                     VMSGKKYAYIESKDEAFIDEVSTYYAKFKVVDDLTKVEGDILKIAIFDFKGAEHNNSI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEYLKEIARFRAKRNTENGVVDKIKEVMKIG"
     gene            complement(27899..28369)
                     /locus_tag="PC592_002057"
     CDS             complement(27899..28369)
                     /locus_tag="PC592_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HDF4056030.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEYIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENAPQIENKILSIIKK"
     gene            28508..29152
                     /gene="uppS"
                     /locus_tag="PC592_002058"
     CDS             28508..29152
                     /gene="uppS"
                     /locus_tag="PC592_002058"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HDF4056031.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29195..30100
                     /locus_tag="PC592_002059"
     CDS             29195..30100
                     /locus_tag="PC592_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4056032.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKVTQGVVALVKSMDKGNKTSQQQNVNSE
                     QFDLGNEEENKNKKYTVFIDPGHGGNDKGTESKTSHRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSDEQKIIN
                     EKYQEQLAEGIVQGVLSYLDSKGNK"
     gene            30412..31959
                     /locus_tag="PC592_002060"
     CDS             30412..31959
                     /locus_tag="PC592_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4056033.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIGVGVKVLILILL
                     ILFSINVFISHLKIQVYEDKINLGLINNPDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKYYFGKEAIYVKLKSAVFVLIIKLED
                     REQKIPYLVNLIKNKIVILNQIDNFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     IKSKRLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMIAPNKFIPIAEKNGLINNIGRWLIQEVFGTINKWILEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDVIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMNQVKVLSELGCNFIQGYVFFKPLDEINYKRLLTDGSYINLEDTLLDK
                     CMAVEEE"
     gene            31962..32360
                     /locus_tag="PC592_002061"
     CDS             31962..32360
                     /locus_tag="PC592_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF4056034.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDNPIDAKMILKNEEIPTLTLYRL
                     LRKLCANNILTFNKEDGKKYMLNVSLDTISLRTIVEAIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32400..34133
                     /locus_tag="PC592_002062"
     CDS             32400..34133
                     /locus_tag="PC592_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF4056035.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     SHILNYCIYGADIDEKAISILKDSLINKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKKTYID
                     VFKIKNEDICINKFEILEELLKSSKFEHFNINQRLLSDEWILVNKEDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYVVDKSEY
                     RLIYSNDIDNENTNKKILDEIIGIYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLGIFSYEYLVGILNSSIYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYDEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34365..35576
                     /locus_tag="PC592_002063"
     CDS             34365..35576
                     /locus_tag="PC592_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF4056036.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDVSLRTVMESIIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRKLASNFEIRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35768..36028
                     /locus_tag="PC592_002064"
     CDS             35768..36028
                     /locus_tag="PC592_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDF4056037.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
BASE COUNT        14495 a         3786 c         6390 g        11583 t
ORIGIN      
        1 aatagcaata gcaatagcaa tagcaatagc aatagcaata aaatttcaaa taatagtata
       61 gattctaaat ttgtgaatag tagagttaaa tcaatagata taataagagg gctatcaata
      121 gccctcatga tagtttgtaa taatcctggg acttggatga gaatgtatcc tcaacttaga
      181 catgctgtat ggcatggtgt aacacttgca gattttgcat ttcctttttt tgttatatcc
      241 ttaggtgtta caattccaat atcaataaat agtaaactaa aaaataataa atctacatta
      301 agtataatac ttagtatatt caagagaagt atcttattga tattatttgg atttttctta
      361 aattacctag gaaatcctga tttaaatact gtaagaatac ttggagtact tcaacgtatg
      421 ggactagtct attttgtgac tagcttagta tacttactac taaaaaaatt aaatgttaga
      481 agttctgtta caataattac tttcttatgt atatctgcat ttataatagt aggatattac
      541 atagtagcaa aaccttatgg gtttgagtta gaaggttctc ttgcacaatt agtggattta
      601 catttcttta aaggtcattt gtacaagcca gattttgagc cagatggttt tttaactagt
      661 atagtagcaa tttcttcagg aatgttggga tgcatgatgg gatgtgtgct tttaaaagaa
      721 aacataggag agtataaaaa attctttaaa atattagtta tgagtattat tttactaata
      781 ggtgctttta tatttaatca gtattttcca tttaataaaa gattatggtc tagctcattt
      841 gtacttttaa tggctggaag ttatggtata ttactgtcaa tattttattt tatatgtgac
      901 atcaaaaata aaagtaaaat atttacccca ataatagcac ttggaagtag ccctattttt
      961 acatatatgt gtctcgagat attaagccat gttttttgga accttccaaa acttacaaac
     1021 aaagtcgatt atccaactac cttggtagag tggactacat atgaacttat aactccttgg
     1081 gcaggtacaa cttgggattc tcttgtattt tctttattgt atgtcctatt ctgggttata
     1141 gtaatgtcta ttatgtataa gaaaaaaata tttatcaaaa tttagtgcaa tatttttaga
     1201 cgctaaagtc tttgttttgt ttaaatatac ggaaactatc aaatataatc aaaatttccc
     1261 ctcgataaaa tttaaaaacc atgccataaa agattacaaa aagtttacaa tttgtaattt
     1321 tttgtgctat aatgaaaaaa gatttacata atattgaatt tatgtaatat aaaacaagct
     1381 taagatgtat taaaaaagat ttaaagattt aaaggtccaa aaaatttagg ggggatatga
     1441 tgaaaaaaac aacaaaatta ttggcaacag gaatggtgtc tgtagcaatg gtggcaccaa
     1501 acgtagcttt agcggcggaa aatactactg caaatacaga atctaactca gatattaata
     1561 taaatttaca aagaaaaagt gtagtgttag gaagtaaatc taatgcaagt gtaaaattta
     1621 aagaaaaatt aaatgctgat tcaataacat taaattttat gtgttatgat atgccacttg
     1681 aagctacttt aaattacaat gaaaagacag attcatatga aggtgtaata aactataaca
     1741 aagacccaga atacttaaat gtatgggaac ttcaaagcat aaaaataaat ggcaaagatg
     1801 aacagaaagt tttaaacaaa gaagacttag agtctatggg attaaatctt aaggattatg
     1861 atgttacaca agagtttata ataagtgatg caaattcaac aaaagcagta aatgaatata
     1921 tgagaaaaac ttctgcacca gtaaaaaaac ttgctgggcc tactagattt gaaactgctg
     1981 ttgagataag taaacaaggt tggaaagatg ggtctagtaa ggttgtaata gttaatggag
     2041 aattagcagc agatggaatc acagctactc cacttgcatc tacatatgat gcaccaatat
     2101 tacttgcaaa taaagatgat ataccagaaa gtacaaaggc agaattaaaa cgtctaaacc
     2161 caagtgatgt aataatcata ggtgatgatg gttcagtttc acaaaaggca gtatctcaaa
     2221 ttaaatctgc tgtaaatgta aatataactc gtattggtgg agttgataga catgaaacat
     2281 ctttacttat agcaaaagaa atagataaat atcatgatgt taataaaata tacatagcaa
     2341 atggatatgc tggtgaatat gatgctctta acatttcatc aaaagctggt gaagaccaac
     2401 agcctataat attagctaat aaagattctg taccacaaaa tacatatgat tggttatctt
     2461 cacaaggttt agaagaagct tattacatag gtggtagtca aagtttatca tcaaaaatta
     2521 tagacaaaat atctaaaata gcaaaaaacg ggacttcaaa aaatagaatt tctggagcag
     2581 atagacatga aacaaatgca aatgtaatta agactttcta tccagataaa gagttgagtg
     2641 caatgttagt tgcaaaatct gacataatag ttgattcaat aacagcagga cctttagcag
     2701 ctaaattaaa agctccaata cttataactc caaaaactta tgtttctgca taccatagta
     2761 caaatttatc agaaaaaaca gcagaaacag tatatcagat tggtgatgga atgaaagata
     2821 gtgttataag ttctatagca tctagtttgt caaaacataa tgcaccaaca gaaccagata
     2881 actcaggttc agcagcagga aaaactgtag tgatagaccc aggtcatggg ggttctgatt
     2941 caggggcaac aagtggacta aatggtggag cacaagaaaa gaaatatact cttaatacag
     3001 cattagcaac tactgaatat ttacgttcaa aaggtataaa tgttgttatg actagagata
     3061 cagacaaaac aatggcttta ggagaaagaa cagcattatc aaatacaata aagccagatt
     3121 tatttacaag tatacattac aatgcatcta atggagctgg taatggcgta gaaatatttt
     3181 acaaggtgaa agataaaaat ggtggaacaa ctaagactgc agcatcaaat atattaaaaa
     3241 gaatactaga aaaatttaac atgcaaaata gaggaatcaa gacaagaaca cttgcaaatg
     3301 gaaatgatta cctatatgtg ttaagaaata ataattatcc agcaatactt gttgaatgtg
     3361 catttattga caataagagc gatatggata agttaaatac tacagaaaaa gtaaaaacaa
     3421 tgggaactca aataggcata ggaatagaag atacagtaaa ataaaataaa aaatattaaa
     3481 gcaaaacata tcatctcctg ttataatgta aaatataaca agagatgata tatttttgta
     3541 aagaatcaaa ttgtttacaa tgatgtttct tgtattgata atctgctcat tattgagtat
     3601 aatatagaaa taagtcaaaa ataagataga aataagttga aattaagaat taaaaaaatt
     3661 tttattccaa tatggaggta actatgtctg gatatactaa tgatgagtgt gaaataccta
     3721 aaattaaaag ctatccaggg gcagataaag aaattgcaag cgagattgac tatagcatag
     3781 taaaaggaac agttttattt gacttgtacc aaagaattat ggatttagtt ttatctataa
     3841 taggacttgt gataggttta cctttaatag caatatttgg aattcttatt aaaatagagg
     3901 acaaaggacc aataacttat aagcaagaaa gactaggaaa atgcgggaga agattctata
     3961 tatataaatt aagatctatg agaacagacg cagaaaaatt tggcgcacaa tgggctgaaa
     4021 aagatgatcc tagaataact aaggttggaa agtttattag gaaaactaga attgatgaga
     4081 ttccacagct gtttaatata ttaaaggggg acatgggctt aataggtcct agaccagaga
     4141 gaccgaactt tactgttcaa tttaatgagg aaatacctgg atttatcaac aggctcgcta
     4201 taaaacctgg gcttacgggt tgggcacaag taaatggtgg atacgaaatc actcctgaag
     4261 aaaaacttaa agaagatatt tactatataa aaaataggag tatattactt gactttaaga
     4321 tactctttaa aactgttaaa gtagtattga caggagacgg agctagataa ttttaaaata
     4381 ttagattact aatcaatgaa aaagctcttt aaaaagagct tttttattgt caaaaaatac
     4441 aaaaaagaaa aggaatgaga acttatgatt aaaaaaattt ctactatatt atcgttagtt
     4501 ttgttaatct ctatttctag tactatgtgg gtatttgcag atgcaaagcc caaaagagag
     4561 ttgatagaag ggagtatacc agagatttcg acagaattaa ataaaagagc atttaaggat
     4621 tctaaagaag taattcttgt aaatgaagat tcaattgtag atagtataag tgcaacacct
     4681 ttagcatatg caaagaatgc tccaatagtt gtaactaaga gtaaaaatct tggtagagta
     4741 acaagaaatt atctaaaaga actaggtcca gagaaggtta cgatagtagg tggtttaaag
     4801 gcagtatcta aagatgctga acgtaatata gaaaaaatgg gaatgaaagt agaaagaata
     4861 agaggaaaag acagatatga tacatcttta aagatagcta gagaaatgta cagaacagta
     4921 ggatttgatg aagcattttt acttagctca acaacaggat tagagaatgc catatctgta
     4981 tattcttatg ccgctaaaag tggaatgcca ataatatggg ctaaagatga ggggtttgaa
     5041 gaacaaattg atttcttaaa aggtaaaaat cttaaaaaaa tatatgcatt aggtgattca
     5101 aaagaattta ttgcagagat tgattctaac ttaaaaaata tagagggcat aaagcaaata
     5161 aataagtcta gtacaaatgt tgatttaata aagaagtttt atgatgaaaa agatataaag
     5221 aaaatctata ctgctaagtt agactttggt agtagatctg atgtaaacga atatatttct
     5281 ttgggagtag tatcagcaaa agaaaatatg ccaatactga tttgtaatga taatttaagt
     5341 cgtgcacaag ataaattctt gaaagatagc aatataaatg atgtagttga agttgggtac
     5401 acagtaggtg attatagtct atttaagagc atatttaatc taacattctt atcttgtata
     5461 gtattaatac tattattact attgattaca tttagggcac ttagatatga gtcgaaatag
     5521 tttttgattt attaaggaag cttttcatag gttaaattta cttaattaga ataatgttta
     5581 taagcagttt taaaagttct acttttagag tttaaattag ataaggagaa agaagatgtc
     5641 aaaaacagct aaagcagcat tgtggattat ggcagccact atgttttcaa aagtattagg
     5701 tttccttaga gagcttgtac ttgcaaattt ctatggaaca ggtatgtatg cagatgtatt
     5761 tgtactaaca ttaaatatac ctggtttaat catagcagtc ataggttctg cagttgctac
     5821 aacttatata cctatgtact ttgagacaaa gaaaagactt ggagatgaag gtgccttaaa
     5881 atttactaat aatgttttaa atatatgcta tataatggct atagtaatag ctattattgg
     5941 gcttttattt acagagcaat ttgttacagt atttgcagca ggatttagaa acgaccctgc
     6001 aaagttccaa gcagcaatat tatttactaa aataatgatt tcaggagttt tattcctgag
     6061 tggaagtaaa atatttagtt cgtttttaca ggtgaatgac agttttgtaa ttcctgggct
     6121 tataggaatc ccatataata ttataataat agcagcaata gcactaagtg caggtaaaaa
     6181 tgtatggata ctaccagcag gagcactatt ggctatggcg agtcaactat tatttcaact
     6241 tccatttgca tttaagaagt cctataagta taagccatat ataaatttaa aggatgagtc
     6301 cataaaagaa ttagtcaatc tagtattgcc tatgttggta ggagtagctg ttggacagtt
     6361 aaatatattt gttgatagat tattggcaac tactttgggt gatggaaagc tgtctgctct
     6421 taactatgca aataggctaa atgagtttgt tatggcatta tttgttacat ctataataac
     6481 agttatatat cctaagttag caaaaatgtc tggtaaagat aataaagaag gatttataag
     6541 tactattgta aaatcgtcaa attgtattat attggtggtg cttcctatat ctataggagc
     6601 tattatatta gcagagcctc ttgttaggat attattccaa aggggtaaat ttgatgcgtt
     6661 atcaacagac cttacatcta tagcgcttag actatattca ctaggtttat tggcctgtgg
     6721 agtaagagat gttttatata gggcatttta ctctctttca gatacaaaaa cgccaatgat
     6781 aaatggaagt atagctttaa taataaatat agttcttaat ttaatattga taagaccatt
     6841 aggtcatgca ggtattgcca tatcaactag tacatccaat ataattacag ttatattatt
     6901 atttatatct cttaaaaaga aaaatggata ttttggagga gataaaatta taaagactgg
     6961 tctaaaaagt ttagtagcat ctggtgtgat ggcagtagtc actttattga tatataataa
     7021 tctatatgca tttataggtt caggaacaat taaagaaatt atatcagttg gtgcaggggt
     7081 actaggtgga gcttctgtat atacgatatt gatagtttta tttaaggtag aggaaatgga
     7141 tttagctttt gaatttttaa gaaaaggaaa acaaaaacta cttagaagat agattcttac
     7201 tttgaaattt taaattagag tcagaaagga tgaaaatatg gattataaga ataattatga
     7261 gatgtggtta aattctcctt attttgatga gcaaacgaaa aatgagctat taagcataaa
     7321 agatgatgaa aaagaaatac aagatagatt ctataaggat ttagagtttg gaacaggtgg
     7381 tttaagaggt ataataggag cgggaactaa tagaatcaat atttatactg ttagacgtgc
     7441 aacacttgga gttttaaatt atatcattaa gactcaagga gaggaaggta aacaaaaggg
     7501 aatagttata gcacatgata gtagatacat gtctagggag ttttgtatag aagtagcaaa
     7561 gactttaagt gcttatggtg taaaggctta tatttttgaa gaattaaagc ctacaccaga
     7621 actttctttt gctgttagat atttaaagtg tgctatggga atagtaataa cagcaagtca
     7681 taatcctaaa gaatacaatg gatataaagt atatgactca gatggtggtc aaatatgtat
     7741 agatgtggca aatgatataa tagcagaagt taataagatt gatgattaca gtgttattaa
     7801 aagtatagat tttgaagaag ctttatctaa aaatttaata actatattag ataatgaggt
     7861 agatgatgaa tttataaaag ctgttaagaa acaagtttta agacaaaata taatagatga
     7921 atatggaaaa aaattgaaaa taatatatac acctattcat ggtacaggaa ataagccagt
     7981 aagaagagtt ttaagtgaat gtggctttga aaatgtaatg gtagttaagg agcaagaatt
     8041 gccggattct aatttttcaa cagtaaagta tcctaatcct gaagaaaaat cagtgtttaa
     8101 tatagctatt gaaatggcaa agagtaatgg tactgatttg ataataggga cagaccctga
     8161 ttgtgataga gtaggtatcg tcgtaaaaga ttcaagtggt gaatatatag tcttaaatgg
     8221 aaatcaagtt ggttcactct tagttagata tatagtagaa agtttagtca aagaaaataa
     8281 acttcctaaa aacaatccta caataataaa aactatagtt acatcagaac taggtgctaa
     8341 aatagcaaag gcttataatg tagattgttt aaacacttta acaggattta aatttatagg
     8401 agaaaaaata aaagcgtttg aaaaaagcaa tgatagaagc tttataatgg gatatgagga
     8461 aagctatggt tacttaattg gaactcatgc tagagataaa gatggtgttg tatcttcact
     8521 tatgatatgt gaaatggcag catactattc ttcaaaaggt atgaacttgt atgaagcttt
     8581 gctagataca tataataaat ttggatacta caaagaggac ttaaagtcag tgactttaaa
     8641 aggtatagat ggaataaaaa aaataaaaga gatgatgctt tactttagaa gtgttaaaat
     8701 agataatgtg gctgatgtaa aagtagataa aattttagat tataaagaag gtgttgatga
     8761 tttacctaaa tcagatgtac ttaaattttt acttgaagat ggctcttgga tagctataag
     8821 accttcaggt acagaaccta aaattaaatt ttactttgga gcaaattcag acaatcaaga
     8881 agatgtagaa tttaaattga acaatttaat atcttatata ttaaatgtag tggattctat
     8941 ataagaggct aaggggagat aaataatgaa agtatataat gtcataatgg ctggaggagg
     9001 aggaactcgt ttctggccac ttagtagaca agaagtacct aaacagctta taaatttaag
     9061 tggagaagat gctttaataa acgaaactat aaacagaata gattctctag caaaaaaaga
     9121 tgatttattt atagtaacca atgagaaaca attggaagct ttaaaggata tagtaaaaga
     9181 taagtgtttg gataggaata tattaccaga gccatgtgcc agaaatacag cagcagctat
     9241 aggctttgca gcatttaata taatgaaaaa atatggtgat ggtgtcatgt gtgtatatcc
     9301 agctgaccat tatataaaag aggaaaaaga atttaaatct attttagaaa aagctatcta
     9361 tatagcagaa aataatgata aactagtaac tattgggata actcctacat ttccatcaac
     9421 aggatatgga tacataaatt ttaatagaga aaacacgata gaggatgttg catatgaggt
     9481 agtagagttt gtagaaaagc caaactatga aattgctaaa gaatatgtaa actctaaaaa
     9541 gtatgtatgg aatagtggca tgttcgtatg gaaggtatct aaaatattag aagattttaa
     9601 aagatacttg ccaaaagtat atgagaaact agaagagata agtaaatact taggaacaaa
     9661 agaagaagtg gaaaaaataa aagaaatata cccaactata caatcaatat ctatagatta
     9721 tggtattatg gaaagaagta atgatgttat agtagttcct ggtgattttg ggtggaatga
     9781 tgttggctct tgggattctc taggtgcaat atatccaact gatgatgaag gtaacatcaa
     9841 aagaggtgaa aatattacta tagatactaa aaattcaatt atatattcag atgataaatt
     9901 aatatcgaca ataggtatta gtgatttgat agtagtatct acgaatgatg cagttatggt
     9961 ttgtagaaaa gataaagctc aagatgtcaa aaaaatagta gagcagttaa aagaagaaga
    10021 tagacaagaa tatatgtagg aggtgttcat ttgattccta aaaaaataca ttatgtatgg
    10081 tttggtggtc caaaaggaaa tatagaaaat atatgtataa attcttggaa agaaaagctt
    10141 ccagaatatg agatagtaga gtggaatgaa aaaaactttg atatagagaa agaaataaaa
    10201 ggaaataagt ttttggaaga atgttataaa agaaagcttt gggcatttat atcagattat
    10261 acaagaataa gagtactcta tgaacaaggt ggagtttata tggatacaga tatgcaaata
    10321 ttaaaggaca taactcctct tttagaagat aataggctta tatgtggata tgaagatgat
    10381 ggagaatata tgaatgcagc tatactaggc gtagaaaaag gacatccttt ttttaaagat
    10441 ttactagagt actatgaaaa agagattctg acttcttcat tatttacaat accaaagatt
    10501 atgactcatc ttatggaaaa gaattataaa aagattgacc aaaataatta tgaagaagga
    10561 atacgtgttt acgataaaga atatttttat ccttttggat ttaaagaaga ctttacaccc
    10621 gagtgtatta cagaaaacac ttatggtata cattggtggg gaaaaagttg ggctaaaaag
    10681 agaaattatt tcttagaaag caaacactta acaggtgtaa ataagatatg gaagtgttgt
    10741 aaaatatttg caagtaatac tttacgaagc taaaagggag aaagtaaaat gaagacttta
    10801 aacgatgata gaaatattat gattagaaaa tatctttata tatttgtttt gtttatcata
    10861 ttacttagaa agtatatgat atcatttatt gacccaaata tggatatagg gatgattaaa
    10921 tcagcgttat tttattcttc aataggaata ctaatgctac tttttttatt tgataagaga
    10981 aaaagtataa cagaaatggt actagttgga gtttgtgtct tactttattt attaaatagg
    11041 gaaggagcta tattattaat cgttttatta gctgtatcag ctaagcaaat agatgataaa
    11101 tttatagtta aaaattattt aataatatcg gcatgttttt taatggtagc tatattatta
    11161 tttaatttat ttccttcatt aatatttaat caggaagtcc actatagata tatagaaaag
    11221 atagatatgc ttgttacaag aatggatttt ggacttggta atccaaatag tgtattttat
    11281 catatggtta ctatatatgc agcatatata ttcttaagat ataaagacta taataaatgg
    11341 gatagaataa ttttatttgg ttctgcattt tttgtttatc aaaccacata tagtagaact
    11401 ggatttttta ctatattagc aggattaata tttgtagaaa taataagatg gatagacata
    11461 aaaaaaataa aaggactacc aatgcttcta aagacattac caataatact tactttattt
    11521 agtgtaatta ttggtacagt atttgataag agtactttat taaatagatt attagcaagt
    11581 aggcctaagt tctggaatgt atacttggct gaaaagggga actttctaaa accttttgga
    11641 aattcatata gtcctgctat aaaagcaact aatccgttag atagttctta tgtatatata
    11701 attagtgtac taggagtcgt tgcttgtata ttatttatgt atttgatgta taaaggaata
    11761 gaaagcttta tagaaaaaga taaaaaagca tatttagtag ctttatttat atttttacta
    11821 tactcttttg cagaaaattt attattagaa gcttcattta gttttgcagt agtattacta
    11881 ataaaagaag tgatattaaa tgataaaagg gaaatagatt tgtggaagat gaaaagtagg
    11941 aggtagtaat gttaatatca ttaataatgc caacattaaa tagatatgat gatatatact
    12001 tacttatgga cagcttagaa aatcaaactt acaaaaactt tgaacttata gtagtagacc
    12061 aaaatgataa tagcaaagtt aaagaaatag ttgataaata cattgataag ttagatataa
    12121 agtatataaa aagctctaaa aaaggattga gttataaccg aaatgtaggc atagacaatg
    12181 ctgtagggca aattataggt ttccctgatg atgattgtgt ctacgaaaat gatacattag
    12241 aaaaagttat aaatttcttt aataaaaata aagattataa aatatacagt tgcaaaacta
    12301 tggatgcaaa taaaattgat gcattcaaga aaatgtatga tggaacttgt gatatcacaa
    12361 gttccaacgt tttggatact ataacatcca taactttttt tattgatttt gaaggtaaag
    12421 actatactag atttgatgaa aaattgggtg ttggtggaga gtttggtgct ggtgaagaga
    12481 tagattatgt tttaaactta ttgagtttag gttttaaagg aaaatacttt ggagatgata
    12541 taatttacca tcctgcaaaa aaacattcta aatctaaaga aaagtatcaa aaagattata
    12601 attatggaag aggttttgga gcactttgca aaaaggaaat agtttataga aaaaattata
    12661 agtttgtaaa ggttatggta tcaaaacttg taagaaatat aggaggtctt atattgagtt
    12721 ccaatagaga ttatcatagt gccactataa aaggaagaat taatggattt agacagtaca
    12781 agttataatg aggatggtgt ttatggacaa ggttaaattt ttaataaata tgcttttggc
    12841 tttttttata tatccattta ataagcatag gtttaaaggt agaaatatct ggcttatagg
    12901 tggacattca ggggatatat acaatgataa ttcaaagttt ttttatgagt acatgttgaa
    12961 ggaacataat gatgtagaaa cttattgggt agtaaataaa gacagtaaag tatttgataa
    13021 aattccaggc aaaaaattaa taagaggaag tgtagaaaac tatctgtatt attacaattc
    13081 aaaagctata gtattttcac atgcaccatc agcagatata gcaccataca attttgctgt
    13141 acctgttctt aattattttc ataaaaaaac aataaaagtg tttttaaatc atgggactat
    13201 aagttttaaa aagagaaaac ctatgaacaa aaagttcaaa aatattatag ataacttata
    13261 taaaagctat aatatagtta cagcaagttc tgaatttgaa agaaatgtta tggtaaatga
    13321 ttggggaatg ttagatgact cagtttatat aattggaaat gccagatatg acaatttacc
    13381 aacaaatgaa gttgcacaaa ctcgagatat attatatact cctacatgga gagattggat
    13441 aaaatttagt tcaggaaaat ttacagatac agattatttt aaaaatataa tgaatttttt
    13501 aaatgatgat aaattaaata aaatattaga tgagaaagat ataaatgtaa aaatttatat
    13561 gcatcatctt atgcatgagt ttatagatga tataaaagaa aatataacag gaaaacgaat
    13621 tgtgttttta gataaagggg taactctagc aaatgaaatc agaaaatcag ctgcaaatat
    13681 aactgattat tcaagtgtag ccatagactt tttgtatatg aatagaccta tcttgtttta
    13741 ccaatttgat ttggatgaat atatggaaaa agttgattca tatatagatt taaaaagtga
    13801 aatgtttggg tctttggctt acaataatga tgaagccgtg aataaactta ttgatattat
    13861 tgaaaataat tttgaggtta tggataacca aaaaaatgaa agaaataagt ttttcagata
    13921 taatgataat aagaactgca agaggatata tgattgtgta ttaagtaaaa ttaaataaat
    13981 attttataaa tgatgaggaa ggtaatatga agaagaattt agtatctata attactccca
    14041 tgtataattc tgaaaaattt attgaagcaa ccataaaatc agtattaaac caaacttatc
    14101 aagaatggga aatgttaatt attgatgatt gctcaacaga taatagtcct aatatagtca
    14161 aatcttatat gcaacaggat agtagaataa aatgtataaa gactgagact aataagggtg
    14221 tctctaatgc tagaaactta gcactaagta aggcaacagg acaatttata gcttttttag
    14281 acagtgatga ccaatggaat agtagtaaat tagaaaaaca agtaaacttt atgttagaaa
    14341 atgactatgt aatttcattt acttcatatg aactgatgga tgaaaatgat aaaaaattaa
    14401 acaaagtaat aaaagttcca cctaatgtag attatagaag attattaaaa ggaaatatct
    14461 taggatgtct taccgttgtg attgataagt ctaaattgga ttttgaaata agaatgagtg
    14521 gtgtaagaca tgaagattat gttttatggt tatcgatatt gaaaaaaggg catattgctc
    14581 atggaataaa tgaagttcta gcgttatata gaaaatctag caattcccta agtggtaata
    14641 aaataaaagc tgctatgtgg acttggaata tatatagaaa tatagaaaaa atacctttat
    14701 acaaagctat atactacttt attaattatg gaataaacgg aatcaaaaaa agttagacag
    14761 agaggaagat ttaattaatg tataaatata aatttactgt atttactcca acgtataata
    14821 gagctcattt acttgaaaat ttgtacaatg atttaaaagc tcaaacttat gatttcaatg
    14881 attttgaatg gttgattgtt gatgatggaa gtagcgacag tactaaagag ttagttgaaa
    14941 aatttatatc agaaaataaa ttaaatataa gatatatata caaagaaaat ggaggaaaac
    15001 atactgcaat aaatctaggt gtaaaaaatg cagatggaga gctatttttc attgtagata
    15061 gtgatgatgg tttaattaaa gattctcttg aaattgctaa tgatgagtgg gattctttag
    15121 agaataaaga aggatttagt ggagttgttg gactttgtgt atatccaagt ggagatttga
    15181 tagggacaga aatgcctgaa gataagaaaa tatgtcactt tgcagaccta tattttaagt
    15241 atggcgttaa gggagataaa agcatagtat ttgtaactga tgagcttata aaatttcctt
    15301 ttccagaaag aaaagaagtg agatttttac cagaaagtgt agtatggaat gaaatgtcta
    15361 aatactataa agttatatgt gtaaataaac ctatgataat aagagattat ttggatgatg
    15421 gtttgactaa gaatatatta agtaaaaatg cattaaaagg tagagcatta gagtttttat
    15481 atttaataaa tcaaaataca tatccattaa gtagatatcc atatatgtgg ataaaaaatt
    15541 acataaattt agccagatac tcattgttgt ctgatagtca ttattttggt gaattaagaa
    15601 aagtatctga taaattgctg tatttagcat tattcccatt aggatattac aaatatattg
    15661 gacaaagaaa attagtatct aagtaaactt gttggtatag tactgctagt tgctatataa
    15721 ggagagtaaa aatatgaatg agcctttagt atcgataatt actcctgttt ataattcaga
    15781 agagttttta tcagagacga taaagtcaat ccaaaatcaa acttataaaa attggcagct
    15841 tttattagtg gatgattgtt ctaaggacaa ttcaagtgaa attataaaaa gttttcgaaa
    15901 agaagatgct agaataaaat atataaagct tgaaaaaaat tctggagctg cagtatctag
    15961 aaatgttggt attaagaatg cggaaggtcg atttattgca tttgtagata gtgatgattt
    16021 atgggatagt agaaaattag agattcagat agaatatatg ttaaaagaaa atataggttt
    16081 ttcttttaca tcttatagat atatgagaca agatgggtca aaaacgaata aggttgcaag
    16141 agctcctaag aaaattgact atgaaggatt acttagaaat actataatag gatgttctac
    16201 agtggtcatt gataaggaga ttgtaggaga gttcagcatg cctttggtaa gaaggggaca
    16261 agatactgca acctggttac agttacttaa aaaggaaaaa tatgcatatg ggattcagga
    16321 agatttagtg aattacagat tagttggaaa ttctatatca agtaacaaga taaaagcatt
    16381 aaaacgaact tggaatactt atagaaatgt tgaaaattta agtttaccaa agagtctata
    16441 tgtattttgt ttctatgttt ttaatgccat taaaaaaaga gtataagttt tatatacttg
    16501 gaggtaaaaa aatgaaaata gctatagctg ggacgggata tgtaggtttg gttacaggtg
    16561 tttgtctagc agaagtaggc aatgaaaatg tagtctgtgt tgatgtagat gaacaaaaag
    16621 ttaagtcaat gaaacttgga atagcaccta tatatgaaga aggcctagaa gaacttatgg
    16681 ttaaaaatta caatagagga agaatagatt acactacaga ctataaaaaa gcttatgaag
    16741 atgtagatgt aatactaata gctgtaggta caccagaaag aagtgatggt tcagctaact
    16801 tagattatat aaaggcagtt gcaaagcaaa tagctgaaac tgtgacaaaa gatactctag
    16861 tagtaataaa atctacagtg ccaattggta caaatgaaga gatagaagat tatataaata
    16921 gaaacttaaa gaatgatgta aaagtggagc ttgcatctaa cccagagttt ttatcacaag
    16981 gtacagcagt aaaagatact ttgcatgctt caagaatcgt tataggtgta gaaagtgaat
    17041 gggctagaga tatattacaa caaatttatg agccttttaa tcaacctata atagttacaa
    17101 atagaaatag tgctgaaatg ataaagtatg catcaaataa cttcttggct cttaaaatat
    17161 catttatgaa tgatattgca aatctttgtg aaatagcagg agctaatata gaagatgtag
    17221 ctttagggat gagttatgat gatagaatag gcagtaaatt tttaaaggct ggaataggat
    17281 atggaggctc ttgctttcca aaagacacaa aagctcttca ctggttatct gaacataatg
    17341 gttatgaatt aaaaacagta aaagcagcaa tagaagttaa tgaaagtcaa aaacttaaat
    17401 tggttagaaa agcttctaaa ctagtagaga gttttcaaga tatgaaggtt gccgttttgg
    17461 gtttgacttt taagccagat actgatgata taagagaagc gccatctata ccaaatataa
    17521 aatatttgct cgaaagaggg gcaagagtta ctgtatacga cccaattggt gtaaataata
    17581 ctaagaaaat atttggtgat tctatacttt atgcggattc tgtagatgat gcgatagaag
    17641 aggcagagat atgttttata atgacagaat ggaaagatgt attaaattat gatatacata
    17701 aatataagga aaagatgaaa aatcctttag ttcttgatgg aagaaattgt tataaagtta
    17761 aagatatgga agagttagga attgagtatt attcgatagg aaggtaaata ttatgaagac
    17821 tgtttgttat ttagctgatg ggtcaaatcc tcatacttta aaatggtgta gtttttttaa
    17881 aaataaagga tatgacattc atgtaatctc tttaaatgga ggccacatgg aaggaataaa
    17941 aatttataac tttggttcta atgtagaaga actaaaaaat gaaaatattt ctaaaaaaac
    18001 aggatactta ggttcagtaa agcagataaa gaagctagta aatgaaataa agccagatat
    18061 attgcatgca cagtatgcaa gtagttatgg atttatagga agtctacttg ggtatcatcc
    18121 atatattatt tctgtttggg gtactgatat ttatgatttc cctaataatg gttttataca
    18181 aaaacaaatt ataaaacata actttagaaa agcagactat atcttttcaa atagtagaga
    18241 tatggctaaa gaggctaata aatatacagc taaacatgta gatgtaacct tttttggagt
    18301 agatatggat aggtttaagc ctatggaagt agaaaaagaa gatgcttttg taataggaat
    18361 tataaagagt ttagaaaaaa aatacggaat agaatattta atacaagcat ttaagatgct
    18421 taaagatgaa tataaagata agaaaataat tcttaaaata ggtggttctg gaagtcagat
    18481 ggacaaccta ataaatttaa ctaaagaatt gggtatagaa gatgatgttc agtttttggg
    18541 aagaatatct ccagaaaatg taagcaagac ttttaattct tttgatgtaa ctgtgtttcc
    18601 ttctttaaga gagggatttg gagtggcagc tatagaatca gaagcgtgtg aagtacctgt
    18661 tatagttaca aatgtaggag gtcatccaga atctgtatgg gaaaatgaaa cgggcttaat
    18721 tgtagaacca aaacaaccag aagaaataaa aaatgctata ataaaactaa tggaaaatga
    18781 tgaacttaga cttagtatgg gtaagaaggg tcgtcaattt gttagagaaa attatgaagt
    18841 taatttaaac tttaatgata tagaaaaaat ttatgattct atatttgata aatataaaaa
    18901 ataaaatgaa aaatacagca aaagatagat gttgttggct atgcttaggt gcgtagcttt
    18961 tgctgtttaa aggagggctt ctagttatgc gagaaagtat agatttagag aaagaaagct
    19021 tttttaatag gctttttaaa aaatataaat ttagacattt aacactatta attctagata
    19081 tttgtagcgt actagtagcg tttcgaatgt ctttaagctt gacaggtaat ttaaatgtat
    19141 ttaccactaa tgatataata atttcagctt gtatatatat agtacttcat atagtatcat
    19201 ttagattgtt taagtgttac aacacactat ggagatatgc aggagaagaa gaaatcatat
    19261 ctatttttat ggcaacttta gcttatttaa ttccagttta tataataaat aaattattag
    19321 ggtttgatta tcctataata ttttatgtac taaatacaat atttattata atgtttacaa
    19381 gtggcgcaag aatagcctat agagctataa gaatagtcat gaataagaca tattctagag
    19441 gcaagatttc aaatatcctt ataattggtg caggagatgc aggagaaatg gttatacagg
    19501 aactaaaaag aaatccagaa cttaagaaag tagcagtggc tataattgat gatgataaaa
    19561 ataaaattgg aagaataatc cataatgtaa aaattgtagg gacaacttca aatataaaag
    19621 aggtagttga aaagtacaat gtagatgaga taatcttttc aatagcaaat atagagaaac
    19681 gtagaaaaaa agagattatt gatatatgta aaaacactaa ctgtaaaata aagacaatac
    19741 caggaattta cgaaattata gatggaaaag ttgatataaa acagattaga gaagtagata
    19801 tagaagactt gttgggcaga gagcccataa aaacaaattt aagagagata agtaattata
    19861 ttgagggaaa agtaatccta ataactggag gaggaggctc aattggttca gagctttgca
    19921 gacagattgc aggatttaat cctaaagagc ttattatagt tgataattat gaaaacaatg
    19981 cttactcaat acaacaagaa ttacttagaa aatataaaaa taaattagac ttaaagaccg
    20041 taatagcatc aataagagaa gaaaaaagaa tggatgaaat atttaataaa tataagccag
    20101 aagtagtatt tcatgcagca gcacataaac atgttcccct tatggagtcg agccctggcg
    20161 aagctataaa gaataatata tttggaactt taaatatagc tggattatct tcaaaatata
    20221 gagctaagaa atttgtcctt atatctacgg ataaggctgt aaaccctact aatataatgg
    20281 gagctactaa aagagctgct gaaatgatta tacagactat gaatgctgaa agccagactg
    20341 aatttgttgc tgttagattt ggaaatgtac ttggtagtaa tggtagtgta attccacttt
    20401 ttaagaagca aattgaagat ggtggaccag tgacagttac tcatccagat atcattagat
    20461 attttatgac aataccagaa gcagtaggtt tagttataca agctggagct atggctaaag
    20521 gtggagaaat atttgtgctt gatatgggag agcctgtaag aatattggat ttagcaaaaa
    20581 atttaattaa attcagtgga tttgagccag atgttgatat aaaaattgaa ttttctggtc
    20641 ttagaccagg agaaaagttg tatgaagaac tacttatgtc agaagaaggt ctattggata
    20701 cagagcataa aaagattttt attggtagac caatagatgt tgatagagaa aaaataacaa
    20761 aatacttaaa acttttaaga gaaattacta acaatgaaga ggttgaaaaa atagatggta
    20821 ttatgaggga attagtacca acttatatta aaccagaaga tgctaatatc aaagaaattg
    20881 caacaactag agaaaagtag aatatatttc taatttgtaa ccagggggag caaaaagaaa
    20941 caaatatgtg ctaaaaagaa acaaaagatt acaaaaagat tacaaaaaag gttgcaattt
    21001 attttgatgt aagatagaat gttaattagg aattggaaac gaaggaacaa aatgttaaat
    21061 tttcgaaagg attaggtatt tgagattatg atgaatatta aaaataaaaa acatatattg
    21121 aaaaaattta tagctatggt gttaatagca ggagttgtaa cagtagaagc aggagcaata
    21181 acagctagtg cagcagagct aactaattca cctatgagtg caacagtaga ccagtgtgat
    21241 tttttaaatg taagaagtgg agctagtgca aatgatgcag tagtaggaaa gataaacaca
    21301 ggagacaaag ttgaagtctt agaattacat tcaaatggat ggattaaaat aaaaactgtc
    21361 gacaatgtta caggatgggt aaatggagat tatttaacta ttcaaggtgg aaatgtagat
    21421 gcaaaggtac aaaatgtttt aaacttagca tttaagcaac aaggtaagcc atatagatgg
    21481 ggagcaactg gaccaaattc ttttgattgt tctgggttca cttcttatgt ctataaaaat
    21541 ggagcaggag ttaatttacc aagagtatca agatcacaag caacagtagg aaagaaagta
    21601 tcaagagcag aattaaaacc aggagattta gttttctttg gttcaggcgg ttcaataaat
    21661 catgttggat tgtatgtagg aaattctaaa ttcatacatt caccacaaac aggagatgta
    21721 gtaaaagtta ctagcatggc tccaggaact aattatgcaa gaagacttat aactgctaca
    21781 cgtgttttac aataataata gatattgatt tacataggat tgaatattaa cattaagtat
    21841 ataattacat ttaatgtttt acatagagat ttaagagttt agtaatatta aaatagtgat
    21901 gaacgttata aaaacagcaa agaagataaa tttctttgct gtttttttat aataaattat
    21961 ttcatattat aatcaaatat aaaatataaa ttttaactat attattcaat atttgacaga
    22021 taatatgaat tttagatata cttgataaga agtatatttt agaaaaaata aatttaaaaa
    22081 attaaggggg atgaaatgaa aaaaataagt atattagtat tatcattgat aatgacactt
    22141 actatgtgca gtgtaagttc atttgctgat tcgtcaaatg ataaggaaat gagagctgct
    22201 tggatatcta cagtttataa tttagactgg cctaaaacta agaacaatga agccaagcaa
    22261 aaaaaggaat acacagattt attggacaaa ttaaaaagtg taggaataaa tacagcagtg
    22321 gttcaagtaa gaccaaaatc agatgcttta tataaatcaa atataaaccc atggtctgaa
    22381 tatcttacag gtacacaagg taaagaccct ggatatgacc cattaccatt tttaatagaa
    22441 gaagcacata aaagaggaat ggaatttcat gcgtggttta atccatatag aataactatg
    22501 gcagatgaga gcatagataa attgccagca aacaatccag caaagaaaaa tccaagttgg
    22561 gtagttaaac atggaaataa gtattactat gacccaggtt taccagaagt tagaaagtac
    22621 atagtggata gtatagcaga agtagttcaa aattacgata tagatggagt tcattttgat
    22681 gattatttct atccaggagt aagtttcaat gatactgcta cataccaaaa atatggaaat
    22741 ggacaaaata aagataattg gagaagagaa aatgtaaata ctctacttag agatgtaaaa
    22801 gcgtctataa agagtataaa gcctaatgtt gtatttggtg taagcccagc aggtatatgg
    22861 agaaataaga gtagtgaccc aacaggttca gatacatcag gcaatgaaag ttatgtaggt
    22921 acatatgcag atacaagagc atggataaaa caaggattga ttgactatgt agttccacaa
    22981 ctttactggc caattggtct taaagcagca gattattcta agttagtgtc atggtgggct
    23041 aatgaagtaa aaggaacaaa cgtagattta tacataggac aaggtatata taagcaaggt
    23101 caatcaagtt atggtggaca aaatatagca aaagaaatag tgcaacaagt aacattaaat
    23161 agaaagtata gtgaaataaa aggtagtatg tatttctcag ctaaagatat agcaaatagt
    23221 agctctatac aaaaggattt aaagagctta tattctagta gcgaagaacc agttactcca
    23281 ccatctaatg ttaaagtgga gaaattaaga ggcgacgaaa ggtatgatac agcagtagca
    23341 ataagtaaaa aaggctggcc tacaaattca gatacagtag tattagtaaa tggatactct
    23401 atagttgatg gtataacatc aacaccactt gctacatcaa atgatgctcc tatactattg
    23461 gtaaataagg ataatatacc tacatctact aagaatgagt taaaaagact taatccaagt
    23521 aaagttattt taattggagg aaatagctct attggagata aagttgagag tgagataaaa
    23581 gatacactgt caaatgtatc aataaataga gttggtggtt cagatagata tagtacatct
    23641 ttaatgatag caaaagaatt agtaaaaaat aatccagtag aaaaactata tataacaagt
    23701 ggtacaggtg aagcagactc tctttctata gcttcaaaag caggagaaga aaagcaacca
    23761 atagtactag tatcaaaaga taatgtaagt gatgaagttt acaattggat atcagactta
    23821 aaagtaaaag atgcttattt tataggtggt aatctaagta tatctgattc agtaataaat
    23881 aagttggata aagtcattac aaatgatgtt tctaaaaata gaatagctgg agaaaataga
    23941 gaagagacaa atggaaaagt aatacaaaaa ttctatccaa atgctgaata ctcatcaatg
    24001 tttgtaagta aaagtaatca attggtagat gcattaacat caggtccttt agcagctaaa
    24061 ttaaaatcac cagtagttat gcttggaaat agcgtaacat ctgctcagaa aactgcttta
    24121 gagcctaaga aaactaatct agtatataca gctggagatg gaataaatca aaatacatta
    24181 aatgctttct taaacttggt taattaataa aaaagttaat ttaggataaa atttctttta
    24241 tagatgtaga ttaaaatgaa tattattaag aaaaattaga aaataaaaaa gaactatatg
    24301 cattttgtaa tcaagtgtac acagtagctt gaaaataatt atgcgatata gttctttttt
    24361 actaattaat cttatacttt gtaataaact ttatattaaa ttttttattg tttaaactct
    24421 atgtcattaa atataaaatc atgtaatatg tctaaagtat ctgggtcaaa tctaagaacc
    24481 catccagctt ttccatatat accacctgta ctatgaattt catcatcaat aggaaattca
    24541 aattgcttaa tatttaagtc ccccattttt aaaacttgag ctcctaaaga aagtattgca
    24601 ttaggcttca tgttagtttt aacatatgga agaactgcat ctaataatcc tggatattta
    24661 gtaacaggta aagtttctgt tttcttgatt atagcttgta taatctgtct ctgtcttcca
    24721 tctctagcaa aggctgtatc attgtgtctg atacgtgcaa aagatagtgc ctgatatcca
    24781 tttagagtct gctttccagc gtttctaatg tattgtatgc tacctttatc atcactttta
    24841 ttccatttat aagtctcagg aataaattta tttagttctc gtatttctcc tttttcaatg
    24901 gtaacttcaa cgccaccaat agcatcaatt atatacataa atgattcgaa attaacacaa
    24961 gcgtaatttt gaatatcaat attaaaattc tcttcaattg tttgtattaa taaatcagct
    25021 tgtccataag cataagcatg agtaagtttt tgtttaccat gaccagggat gtctacatag
    25081 ctatcacgag ctaatgatgt aagtttgata tcattgtgct tgttatcaat agtaagtatc
    25141 atcatagcat ctgaccttga agaatcttca tttggtctag catctgttcc cataagtagt
    25201 atattaatta tcccatcttc atttttatgg tcattgttat ctaataaatc actacttatg
    25261 ctcgagtcat gaatagcaga taatttataa taaaaatatc catagacgct tatagggaat
    25321 attactacca agaaagccag tagtataaca aatttcttta attttgacaa aagtacccct
    25381 tctttcttct ttttcctgta tattttttaa tagcatacac ttaattatat taaagtattg
    25441 aaatatattc aatacttgtt tcagttacaa aaaaaagaca atgatataat ttataagaaa
    25501 atttatcgac ttatatatac aattaaaagt atatataata tattttttaa aagtaattta
    25561 tattttaaaa taaaaacaca ccccgtaaat gcaaaataat ttgcatttaa gaggtatgta
    25621 tttatcatca aattattagt ttgttttgaa atttctaatc ttcaaccata atgtctttaa
    25681 atatgaaatc atgcattgca tctagttcat attcctcaaa aggtattaca tagcctgcat
    25741 tacctatttt tctaccattt tcagtagaaa gaggaaattc catagatttc aaatctaaat
    25801 ttcctatact taaaagttct tttcctaaag atattatttc attaggattc atattagttt
    25861 ttacatacgg aagtattgta ttaactagac tagggtattt agtgactggt aaatccttaa
    25921 caccatttat taaactctgt atgacacttc tttgtcttct atctctttca tctgtactat
    25981 cgttttttct tatacgagaa aatgcaagtg tttgatatcc atttaatttt tgctcaccag
    26041 aatttcttat atatttaaga gaacctttat tgtcattttt attccattta taagtttcag
    26101 gtataaattt atttaattct cttatttcac tcttatcaac agtaacagta actccaccta
    26161 gagcatcaac tatatccata aaagagaaaa agtcaactac agcgtagttt tgtatatcaa
    26221 gttggaagtt ttcttctata gtttctatta ataaattagc ttgtccatat acataggcat
    26281 gtgttaattt ttgttctcca cgtcctggta tattaacata agtatctcta ttcaatgaag
    26341 ttagtttaag acttttattt ttattatcaa tagtaagtat catcatggca tcagaacgag
    26401 aaacttcttc tcctggtctt gcatctgtac ctaacaataa tatgtttgtg atattttctt
    26461 cgtttttata gtcattacta ctaagcgcct ctgtatttat actatcatct tgtatagttt
    26521 ttaatttagt aaaaacatat ccatatatac taacaggaaa tgctataact aaaagggcta
    26581 gaaatataac gaactttttg agtcctgaca ataatatccc ctactttcta aattttttaa
    26641 ttacacatag ttaattatat taaaaattta ctacataagc aataaaaaac acaataaatt
    26701 agcataagtt tgtcataata taattatttt tatagtattt tatagaagaa agtgtgtagt
    26761 tattattaat tttattggaa tataattgta tgaagaatta aatttttata aactggtgtg
    26821 tatattgaaa aaaatatttt cctgaatgta gttatagcat cttattgaaa ggtgtaaatt
    26881 gtaatttaaa atttttagtg tataataaga attgaaaatt taaactgata aaaattaata
    26941 aaaaataatt atagattaat aatttggggg aggaaatgta tgataaaatt aatagcaaca
    27001 gatttagatg gaactttgtt agatgaaaag agcgaaataa atccagagtt ttataaagta
    27061 tttaaaaaat taagagagag aggaataatg ttttctgctg ctagtggcag gcagtatcaa
    27121 aatcttataa aaaaatttga agctataaaa gatgatatga tgtttatctc agaaaatgga
    27181 acattggtag tatataaagg aaaagagata ttatcaaatc ctttggataa agaattagta
    27241 aatgaaatta tagagacaac aagaagcata gaaggtaaga aaatcgtaat gagtggtaaa
    27301 aaatacgctt atatagaaag taaagatgaa gcctttatag atgaagttag tacttactat
    27361 gcaaagttta aagttgtaga tgacttgact aaggtagaag gtgatatatt aaagatagcc
    27421 atatttgact ttaaaggagc agagcataat aatagcatct actttgaaaa gttttctgat
    27481 agagctcaag tatgtatttc tggagtagaa tggcttgatt taactgcaaa aggtgcaaat
    27541 aaaggaagtg ctataaaaaa agtacaaaaa atgttagata taaaatatga agaaactatg
    27601 gtatttggcg accaattaaa tgatgttgaa atgatgaaaa gtgcttatca tagttatgcc
    27661 atggaaaatg caaatgagta tttgaaagaa attgctagat tcagagcaaa aagaaatact
    27721 gagaatggcg ttgtagataa gataaaagag gtcatgaaaa taggatagtc atatgtatgg
    27781 atgaaaagat tattttgaga aactaaaaaa atatcaatgt aattttgata aataaattta
    27841 tttatgtgaa aattacattg atatttaata aacatcaata agaatcaata agagatattt
    27901 atttttttat tatactcagt atcttgtttt ctatttgagg tgcattttca gcagaaatta
    27961 aataaacata tctacctgcc ttctcaatta tagtattatt tgctatttca gaattgattt
    28021 tttctccatg tccttctcca aaaggtgctt gtatcatatc ttttttataa ttttctagag
    28081 ttttatagat tttatctacc tcgtcagttt ttatgacaat aatatcttct agagataatt
    28141 tttcagaaga attaattaca aaaccttgaa tgatgtattc ctccacatca ttaaaatagt
    28201 taaagtcctt tgcatcaaag atttttgatt cttttataag taaatcagaa gattttaatg
    28261 cttttttaat ttttgatgta gaaacgtttt tataatcacc acttgaagaa caactaacca
    28321 ttcctaatga taagattatc gaaaaaaaca atattaaaat ttttttcatg ataaacctcc
    28381 aagtttttta aactctgtct taaattagtt tactacataa ttatataaaa ataaatgtat
    28441 ttaatgttac agttttgatt aataatgtaa tattttgata ataataccta ttaagaggtg
    28501 attagaaatg agaataccaa aacatgtagg aattatacca gatggaaaca gaagatgggc
    28561 aagtcaaaat ggtatgacaa aagataaagg atatgaaagt ggaatagacc ctggactaga
    28621 gtcttataga ttatgtagag atttgggctg tgaagaggta actttttatg gatttacaac
    28681 tgataataca agacgtccgt cagtgcagac aaaagctttt acaaaagcat gtattgatgc
    28741 tgcaaatata ttaatagatg aaggtgcagc tttactagtt gttggaaata caaaatctcc
    28801 aatgtttcca gaagaattat taccatatac taatagaatt aaagctaaag aaggtcaaat
    28861 aaaagcaaat cttctggtaa attacgggtg gtattgggac ttaaataata tatcaggagt
    28921 agaaaatgta aataaaaata atatacagga ttacatacag tcatttgatg tatccagact
    28981 agacttgata atcagatggg ggggaagacg gagattaagt ggtttccttc ctgtgcaatc
    29041 aatttatgca gacttttatg ttatagataa ttattggcca gattttaaga gtgacgatat
    29101 aaaggatgca tttagttggt atgatacaca agatgtcact ttaggtggat aattaaaaat
    29161 attctgattt aaggttgtag agtgttttaa attattgaaa aaaaaacttc ttgatggtaa
    29221 aataacacta ataatatgta aaagtgtaaa aatttatacc aagaagggtg aagaaatgtc
    29281 aaaaggcaat aataacaata attcaagaaa caaatctaaa aagaccagtc atctgaatag
    29341 aaaaaagcga aaattaaata agaaaaagtt agcagtgttg atttgcttta cagttttatt
    29401 tttatttatt gcatttaagg ttactcaagg tgtagtagct ttggtaaaaa gtatggataa
    29461 aggtaataaa actagccaac aacaaaatgt taactcagaa caatttgacc ttggtaatga
    29521 agaggaaaat aaaaataaaa aatatactgt atttatagat ccaggtcatg gtggcaatga
    29581 taaaggaact gaaagcaaga ctagtcatag atatgaaaaa gacctaaatc tacagattgc
    29641 aaaaaaatta gcaaataaat tatctaaaca aaaggatatt caagtggtag tatctagaac
    29701 tgatgataca tatatatcat taaaggatag agctatctta gcaaataata gttctgctga
    29761 tgtgcttgtt tctattcatt taaatgcaga gaaaaatggg aatacagcaa caggtataga
    29821 aacttggtat aggaataaag ctacagacgg ttcaaaagaa cttgcacaga cagtacaaag
    29881 tactatagta tcctatgtta aagttagaga taggggaata gttgaaaata actttgaagt
    29941 acttagagaa tcaaacatgc ctgctatatt gatagagtgt ggatttttaa caacaccttc
    30001 agatgaacaa aaaataataa atgaaaaata tcaagaacaa cttgcagaag gaattgttca
    30061 aggtgtgctt tcatacttag attctaaagg gaataagtaa gttaacttta ttttaatttg
    30121 aggataaatt taaaaattta atgtgtagat tgtattaact ttatttcgta atgttggaaa
    30181 cgttgtttga atttagaaac tatgaaatta gaaattattt tatctaatct aatttcatag
    30241 ttttttttgt aaaaaattaa taattataaa aatttaaaaa aataaattta gcatagtgta
    30301 atgtggttat ttatatgcga ttttaacttg cattgatttg ctatcaattg tgctttataa
    30361 ttaatatata aagtttaact gtaagataat ttaaaaaata ggggaattta tatgaataaa
    30421 aatagtatga caaaaattta cagtttaaat aaaataattt ttattataat tggaatttta
    30481 ggaatagttt tacttacaag acatattgga gtaggtgtta aggttttaat tttaatttta
    30541 ttaatcttat ttagtataaa tgtatttatt tcacatctta aaattcaggt gtatgaggat
    30601 aaaattaatt taggactaat aaataatcca gacaagttta taaatattac taaagatgag
    30661 aacttcctaa aacatgttca aaactatatc attagtaatg aaaaagaaaa ctgtgtaatg
    30721 gcttgttttg atttatgtag actcaaactt ataaatgata tatatggtta tgagctaggg
    30781 gatgaagtat taaataatat tttaagtaac ttaaaatatt attttggaaa agaagctatt
    30841 tatgtaaagt taaaaagtgc tgtttttgta ttaataataa aacttgaaga tagggaacag
    30901 aagattcctt atttagtaaa tcttattaag aataaaattg tgatactaaa tcagattgat
    30961 aattttaaaa tggatataaa tattgaggct tctattggaa tctataaatt taataataat
    31021 gaaattgata taaaaaaagc tatagataat gctgatatgg caaggattaa atcaaaacga
    31081 ctaaagcaca tagagtatgt agagtttgat aatgctatgg aagaagaaat acaatcaatt
    31141 atgaaaatag agcgagattt attcttagct attaaaaata aagagtttgt aattcactat
    31201 caacctaaag ttgattcaag tacaggtaac attataggtt cagaagcgtt aataagatgg
    31261 ttgcatccat cattaggtat gattgcacca aataagttta tacctatagc tgaaaaaaat
    31321 ggtctgataa acaatattgg tagatggcta attcaggaag tttttggtac cattaacaag
    31381 tggattttag aaggtataaa tgtcttacca gtttcaataa atctttccag agtagaatta
    31441 tataaaaatg atttagttga tttttttaaa ctaatgttta atacatataa tattcccaaa
    31501 gaacttatag aattagaaat tacagaaaca acagcactaa gagatgtaaa atttataagt
    31561 gaaaggcttt atgagattaa atctttaggg atgaatatat cattagatga ttttggagtg
    31621 ggcaattcaa attttatcaa tcttaagggg ataccactag atgttataaa aattgatagg
    31681 tcacttatac tggatatagt tacaaataca aaaacaaagt ttatggtgaa ggcaattgtt
    31741 aacctttcac atgatttaaa tgtaaccgtt atatgtgaag gggtagagga tatgaatcag
    31801 gttaaagttt taagtgaact aggatgtaat ttcatacaag gttatgtatt ttttaaacct
    31861 ttagatgaga ttaattataa gagacttctt actgacggaa gttatataaa tctggaagat
    31921 actcttttag ataaatgcat ggcagttgag gaggagtaag gatgatttca gaagatgtag
    31981 attattcaat aagaatcata agagctatat ttaataatgg agaagataat ccgatagatg
    32041 ctaaaatgat attaaaaaat gaagaaatac caacactaac actatacaga ttgcttagaa
    32101 aactttgtgc gaataatata cttactttta ataaagaaga tggtaagaaa tacatgttaa
    32161 atgtatcatt ggatacaata agcttaagaa ctattgtaga agcaattgat gggaaaatat
    32221 atataaacaa atgtacgaga tatgtatcta attgcagtaa ttgtttaaaa ggttgtaaag
    32281 taaatcgcga attgttagaa atagaaaaag aaatttataa acttttatcg agaaaatcta
    32341 taagacaaat actagaataa aaaattttca gctatgataa taattggagg ttttcggtta
    32401 tggatgatat atctcaagat aattttctac tgtctaaaga gtatgagaat agcttagatg
    32461 tagatactaa aaaagcaagt ggaatatatt atactcctaa aatcattgta gattatattg
    32521 taaaaaaaac tttaaaaaat cacgatataa ttaaaaatcc atatccacga atacttgata
    32581 tttcctgtgg gtgtggaaat tttcttttag aagtatatga tattttatat gacttatttg
    32641 aggaaaatat atatgaattg aaaaagaagt atgatgaaaa ttattggact gttgataaca
    32701 tacacagtca tatattaaac tattgtatat atggtgctga tattgatgaa aaagccataa
    32761 gtatattaaa agatagctta ataaataaaa aggtagtaaa tgatttagat gaatctgata
    32821 taaagattaa tctattttgt tgtgatagtc ttaaaaagaa gtggcgatat aagtttgatt
    32881 acatagttgg taatccacca tatattggtc ataaaaagct tgaaaagaaa tataaaaaat
    32941 ttctcctaga aaaatatagt gaagtttaca aggataaagc tgacttatat ttttgttttt
    33001 ataaaaagat tatagatatt ttaaagcaag gaggaattgg tagtgttata actccaagat
    33061 atttcttaga aagtctatca ggtaaagatt taagagaata tattaaatca aatgtcaatg
    33121 ttcaagaaat agtagatttt ttaggtgcaa atatatttaa aaatataggg gtatctagtt
    33181 gtattctaac ttttgataag aaaaaaacaa aaaagacata tatagatgta tttaaaatca
    33241 aaaatgagga tatatgtata aataaatttg aaatactgga agaacttcta aagagtagca
    33301 aattcgaaca ttttaatata aatcagagat tactatctga cgagtggata cttgtaaata
    33361 aagaggatga aactttttat aataagatac aagaaaaatg taaatacagc ctggaagata
    33421 tagcgataag ttttcaagga ataattacag ggtgtgataa agcatttatt ttaagtaaag
    33481 atgatgtaaa attgaacctt gtagatgata aatttttaaa gtgttggata aaaagtaaga
    33541 atataaataa atatgtagta gataaaagtg aatataggct aatatactca aatgatatag
    33601 ataatgagaa cacaaataaa aagatactag atgaaattat agggatatat aaaacaaagt
    33661 tagaaaacag aagagaatgt aaaagtggaa taaggaaatg gtatgaactt caatggggta
    33721 gagaaaagct tttcttcgaa agaaaaaaga taatgtatcc ttataaatca aatgaaaata
    33781 gatttgctat agattatgat aacaattttt caagtgcaga tgtatattct ttttttataa
    33841 aagaagagta tttaggtata ttttcatatg aatatctagt tggaatttta aattcaagta
    33901 tttatgataa atactttaaa ataactgcta aaaaaatgag taaaaatata tatgattact
    33961 accctaataa ggttatgaag ataaggattt ttagggataa taattatgat gagatagaga
    34021 atttatcaaa gcaaataata tcaattttat taaataagtc tatagataaa ggaaaagtag
    34081 aaaaattgca gataaaaatg gataacttga taatggattc tttaggtata taagcagttg
    34141 taagtgtgaa aaaattataa tttgttaatt gtttatttaa attcacaaat aaaaagttga
    34201 ccatataaaa aatattaaaa atatatactt ttcaatattt ttttgataaa ataagaatga
    34261 atttgtgcaa ttttattttt ctccaataac taaaaatagt tttttgaatt aatatttgct
    34321 gaggaataaa aatcagaaac gtttttgata tagtaggtga taatatgaaa ggattagttt
    34381 tagaaggtgg aggaacaaaa ggagcctacc aaataggtgc atataaagct ttaagagagc
    34441 ttggtataga gtttcaagga gtaactggca catcaattgg tgctttaaat ggagcatata
    34501 taattcaaaa tgatattgaa gtaatggaag atatttggtt aaattatgac tatactcatt
    34561 ttatgaatat tgatagagaa acctatgaga gatttaaaaa tgtagatttc actactaaaa
    34621 atctcaatgc agtgtttgaa cttataaata aagctagaaa aaatgaaggt atagatataa
    34681 gcccattaag acaactaatg gaaacaacat taaatgaaga cataataaga aaatctaaaa
    34741 aagactttgg gcttgttacg gtatggtggg ataaaaagat taatccgtat ccattgtata
    34801 ttgaagatat acctaaagga agattgattg attatttaat tgctagttcc agtttgccta
    34861 tttttcagac gaatatgatg gatgataagt tgtatcttga tggaatgttt tgtgataaca
    34921 tgccaatagg actcttggaa gataaaggtt atgaagatgt tgttgtaatt cggttgattg
    34981 atgattttat tgggaaaatg aatctaaatc gacatcaaaa tataaatata aaaactataa
    35041 taccatcaga atatctagga ggttctctta ataaagatag ggataatgta gaaaaaaaca
    35101 ttcgactagg ttacttagat actatgaaag catatgaaag atgtactggg attaagtatt
    35161 attttgatgt agagtataaa tataatgaag aatattgttt tgataaattt agaagtatga
    35221 gtaatgaaac aatacaatat atttgtaatt tattgaatat aaaaagagat gtttcactta
    35281 gaactgttat ggaaagtata ataccaaagc ttggtgaagt tcttggattg ccaaaggatt
    35341 tttcgtataa agatttgttt tactgtatat atgaaaagaa acttgaagaa aataatataa
    35401 acaggataaa attatatgat tttaacaaag ttatagatgt tgtaaataca aatattgatt
    35461 ctaatagaaa gttagcttct aattttgaaa ttagacctaa aattagtatt aaaaagaaca
    35521 aaaacacaaa attattgaca aattgtatta taaaagacat aaaaaatcaa agttaaataa
    35581 aaaacaaaaa aaaatttgta attatactcg aaaaaagtgt atattagtag tataatattt
    35641 ttgtagcact agtgggaaca aaaaatgacc ataggacaaa aaagtaccac ttagtaccat
    35701 taaagtaaaa aacaggaaaa caattttaaa aaatataaaa tgtaaagttt ataggaggat
    35761 ttaaaaaatg gaaaaagtag ttagtatcaa aaatgcaagt ggattacatg ctagaccagc
    35821 aggaatgttt gttaagaagg cagctgaatt taaatcaaca gtagaggttg tagcaaaaga
    35881 caaaactgta aatgcaaaat caataatggg aataatgagt ttaggtttag ctcaaggaga
    35941 agaattaaag ttagttgtaa atggagaaga tgaagaagta gctttagctg caatggttga
    36001 attagttgaa agtggatttg gagaatagat ataataattt tttaaaattt gatatttaga
    36061 atctaatatt acttaaagta aagtaacaga gaagtattaa acatatacag accaacattt
    36121 gtagatattt aatttctttg ttactttcat gtttatttaa tcagaagatt aagactattg
    36181 ttaattgggt ataaaaatac aaatatttta caaaatgaaa taagatattt ttaatcataa
    36241 attcagaatt aaaa
//
LOCUS       DAMKOJ010000041        35694 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000041 DAMKOJ010000000
VERSION     DAMKOJ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35694
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.043"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            221..361
                     /locus_tag="PC592_002065"
     CDS             221..361
                     /locus_tag="PC592_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056038.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(536..856)
                     /locus_tag="PC592_002066"
     CDS             complement(536..856)
                     /locus_tag="PC592_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF4056039.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NIDK"
     gene            complement(976..1713)
                     /locus_tag="PC592_002067"
     CDS             complement(976..1713)
                     /locus_tag="PC592_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDF4056040.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDIITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGNYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1927..3747
                     /gene="acd"
                     /locus_tag="PC592_002068"
     CDS             1927..3747
                     /gene="acd"
                     /locus_tag="PC592_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDF4056041.1"
                     /translation="MKKKAALATLAMLPLSVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKLNGDSLRTSTNKEKQVT
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLSKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDDSSQSNDKKNTDKFVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADASNNNSNSNSDSSSSNNGNNSSSGQVNGMS
                     GISGAKIDYKSLNYTLASHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSSF
                     VNASSSDIEYYLNPKNFINTTKGMMQFLKINSYRGGISESSLNSYLNGLSSSVFKNQG
                     ATFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFGI
                     GAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYINSSKYNQNTIYKMKWNYDY
                     TWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3960..8258
                     /locus_tag="PC592_002069"
     CDS             3960..8258
                     /locus_tag="PC592_002069"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDF4056042.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKINKERLIRINDREMEEKIRALEIGKVNSCEESEEEGYVIKSEVDEELIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRKEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHPAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEEDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSVGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFNKIPVATGDVHFLDKHEA
                     ILRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIAEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIIVGEKTLLPPMAAIQGLG
                     GNAAINIQTERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8462..8923
                     /locus_tag="PC592_002070"
     CDS             8462..8923
                     /locus_tag="PC592_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDF4056043.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIVNGKEIEFNRKDVAIVRLAIKF"
     gene            8953..10107
                     /gene="nusA"
                     /locus_tag="PC592_002071"
     CDS             8953..10107
                     /gene="nusA"
                     /locus_tag="PC592_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDF4056044.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKKIEAEDVEAEFIEQEELDTSDDNFSDEE"
     gene            10114..10395
                     /locus_tag="PC592_002072"
     CDS             10114..10395
                     /locus_tag="PC592_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDF4056045.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10385..10696
                     /locus_tag="PC592_002073"
     CDS             10385..10696
                     /locus_tag="PC592_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDF4056046.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10718..12658
                     /gene="infB"
                     /locus_tag="PC592_002074"
     CDS             10718..12658
                     /gene="infB"
                     /locus_tag="PC592_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDF4056047.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGDELE
                     LALEMLGEDLSQENGNIIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12701..13081
                     /gene="rbfA"
                     /locus_tag="PC592_002075"
     CDS             12701..13081
                     /gene="rbfA"
                     /locus_tag="PC592_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDF4056048.1"
                     /translation="MASYNRTRRISEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKIDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            13062..14045
                     /locus_tag="PC592_002076"
     CDS             13062..14045
                     /locus_tag="PC592_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDF4056049.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLGFLVEGVKIYKSNEFNMKNYSIIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNAHASSFEMAKNLLVLGAQKNTIIQNIYQSNSYDYYKLLGEA
                     LKALEIFNSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYIDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            14058..14963
                     /gene="truB"
                     /locus_tag="PC592_002077"
     CDS             14058..14963
                     /gene="truB"
                     /locus_tag="PC592_002077"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDF4056050.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEEIKRA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKNIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNSNAIKYYSNGGSIDDKRFLKNNFNKDDEFVRVYST
                     DNFLGLGKLSKHNNIISVKSDKMFI"
     gene            15093..16022
                     /locus_tag="PC592_002078"
     CDS             15093..16022
                     /locus_tag="PC592_002078"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDF4056051.1"
                     /translation="MEIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMASVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            16126..16383
                     /gene="rpsO"
                     /locus_tag="PC592_002079"
     CDS             16126..16383
                     /gene="rpsO"
                     /locus_tag="PC592_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDF4056052.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            16623..17468
                     /locus_tag="PC592_002080"
     CDS             16623..17468
                     /locus_tag="PC592_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF4056053.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFIAEGYHIICMTGAANASGTFQSAMIA
                     KNDVDENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEKIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIITIGCGDNLHDCEILKDEVNKRIKARSVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            17593..19704
                     /gene="pnp"
                     /locus_tag="PC592_002081"
     CDS             17593..19704
                     /gene="pnp"
                     /locus_tag="PC592_002081"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDF4056054.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCIGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            19827..20570
                     /locus_tag="PC592_002082"
     CDS             19827..20570
                     /locus_tag="PC592_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4056055.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDESGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            20728..21975
                     /locus_tag="PC592_002083"
     CDS             20728..21975
                     /locus_tag="PC592_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF4056056.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQLNAFTSKECTCYYVKLIDEHIDIGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLVKKEIENIRENYLTEEEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVDINSVKKVVDK
                     VFNVENIGTCIVGRDVEKILHLN"
     gene            22010..22255
                     /locus_tag="PC592_002084"
     CDS             22010..22255
                     /locus_tag="PC592_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF4056057.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            22265..23488
                     /gene="dapG"
                     /locus_tag="PC592_002085"
     CDS             22265..23488
                     /gene="dapG"
                     /locus_tag="PC592_002085"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF4056058.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKIKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKFITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            23602..24336
                     /locus_tag="PC592_002086"
     CDS             23602..24336
                     /locus_tag="PC592_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HDF4056059.1"
                     /translation="MKDYREDNERFDKDNCSEESSSEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            24459..26867
                     /locus_tag="PC592_002087"
     CDS             24459..26867
                     /locus_tag="PC592_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF4056060.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIVGGWLISIF
                     ALILSVMFIFNISIKDMISNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGRNTDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQ
                     SMPELDVLKELQKATNENPVIDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSNY
                     KKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQ
                     PSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLES
                     EEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYKA
                     NPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFADA
                     QVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVA
                     TQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAK
                     PVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEAI
                     EFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQN
                     LEGE"
     gene            26870..27928
                     /gene="mnmH"
                     /locus_tag="PC592_002088"
     CDS             26870..27928
                     /gene="mnmH"
                     /locus_tag="PC592_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDF4056061.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTIPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNLLVLKECINKF
                     RKRLGHKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYNKVINFNDTEEA
                     LEDVIDLYESILEGENEC"
     gene            27922..29256
                     /gene="rimO"
                     /locus_tag="PC592_002089"
     CDS             27922..29256
                     /gene="rimO"
                     /locus_tag="PC592_002089"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDF4056062.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILRELSEMHQIVSLNDIEFVFNEDLPRYLSTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEDVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEIGEFVSVKINDAMEYDLMGDVLYELA"
     gene            29243..29785
                     /gene="pgsA"
                     /locus_tag="PC592_002090"
     CDS             29243..29785
                     /gene="pgsA"
                     /locus_tag="PC592_002090"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDF4056063.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVLLLLGAQFANGLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            30052..31098
                     /gene="recA"
                     /locus_tag="PC592_002091"
     CDS             30052..31098
                     /gene="recA"
                     /locus_tag="PC592_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDF4056064.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEIDEKVRAFYNLNEEH
                     EEAGNSVSKEIVEE"
     gene            31274..32815
                     /gene="rny"
                     /locus_tag="PC592_002092"
     CDS             31274..32815
                     /gene="rny"
                     /locus_tag="PC592_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDF4056065.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            33125..35461
                     /locus_tag="PC592_002093"
     CDS             33125..35461
                     /locus_tag="PC592_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4056066.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYLYDSVFLVSTKTNNYYHFDGLNRNLSVNNSENQWYYTFLNKEDEYSLNVDNDEA
                     SDNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYDDKFDVVTHLIDDKGFVQ
                     LAVDKTGHEHINFFENSSSDLSNSKKLILNNEKEQKSFWYSSEKSKRYIVCQYIPSLK
                     WYLVLENDFTLMSKQLYMQFLKDIGVIVLIIIFVLFTITHVLKKYKKQIVKLSVSQKL
                     EYQKLLSQSTEGLYENIFEIDITNNRAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKCYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDEEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDDFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     SNNYVLIDKLERFCSKINQKKFAEQAGFSIGCSIGVSMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHVFSEDSTDSISFHIDPRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSTDFNIFSPVLQDDLQMVLDTLKEAISKRETFEVVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISNINTLLENK"
BASE COUNT        14403 a         3776 c         6736 g        10779 t
ORIGIN      
        1 ttcattatat ctcaatttaa tatgtaaaaa atataataat agttagattt tttatatcaa
       61 ttttaatatg taaaatatcc tattgttttg tagatatatc ctaattatgt caaaaaataa
      121 aaaagttttt atttattaga gtttttggaa ataataataa cagatattat aattaattaa
      181 cagtttttgt aagtatttga caatagagag ggtgtaacaa atgggaataa tagagtcagc
      241 atcaaaattg gctgagatgg ttcatttatt ggctgttgaa aaagggataa ctgatataga
      301 agcatgggat gaagctgtga aagaatacag caaaatttac gaagaaagaa gaaatgaata
      361 gaatgataaa aagtgacaac ttgatgataa aaaataactc tatttaaata aattcaattt
      421 ttatagaaac attaaaaata atataaataa aaagatggta tttcaaatgt aagtaaaaaa
      481 tcattttggg ataccatcct tattatttat tttaataata tataagtaat aaattttact
      541 tatcaatatt ttttatgtaa cctctttttt ctagcttttt tatatgctct ttgcgtattt
      601 catcaagatt aataccatac tgttcttcta gcttaaacat catagtaaca catgtctgag
      661 ctacatccat tagttcctta gcagttttct ttataatatc aacttcatct aagtcattat
      721 tttctccact tagatttcta aatttaccta tacattcagc taattcacct tgttcttcac
      781 ccattttgat aaatgtagat tctagggttg ggtctaaatt attaagctct ggtaaagata
      841 tagtttttag tttcataaaa gctcctttca agttattcat atttatacta aaacatcata
      901 acaaaaataa tactaaaaaa aaactttaaa ttcaacataa aaacttacat atataataaa
      961 aatcgtgaaa taaatctata tttgtcttaa tacagcttca tataaaactt ctccaatagg
     1021 tttatttatt acaagagaag ctgacttatc atagactgta tttgctttat taataagagc
     1081 aatataatta cctttgtaat aatctataaa acttgctgct ggatatacag ccaatgatgt
     1141 acctcctata attagtaaat cagcattact tatagcagaa attgttttag taatgatatc
     1201 actatcaaga gcttcctcat aaagtactac atctggtttt actatagaac cacagttatc
     1261 acagtaagga atattaccac caagatttaa catagattct aagtcaaaaa acttaccaca
     1321 tttagtgcaa taatttctat gtacagagcc atgaagctct aggacatttt tacttccagc
     1381 catttgatga agtccatcaa tattttgagt tataacagct ttaagtttac ccatttcttc
     1441 gagttttgct aaagctatgt gagcattgtt gggttttgca ttagggtata ttaatttgtc
     1501 cttataaaat tcaaaaaatt cttctgggta tctaacaaaa aaagtatgtg aaactaattg
     1561 ttcagcagta aattgtttgt tgagtttttg gctaaataat ccagtagagc ttctaaagtc
     1621 tggaatatta gattcagttg aaacacctgc tccaccaaaa aatacaatat tattgtgatt
     1681 agctattaag tcttttaagc tatttgcatc catagttaca cctccaaatt attatatata
     1741 aattgtacta catattaagg tatttatgtt ttattatttc aaataaatac atagtttaat
     1801 aagttaaata aagggaatat aaataaaatg tatacataat ataaataggc aatatttact
     1861 aaaataacaa gttgtcgtat aattatatta aaattgtttt agtgtataag aagggcgggg
     1921 aagtacatga agaaaaaagc agctttagca acattagcta tgttaccctt aagtgtggta
     1981 aatgcacatg ctgatggaga tataggcata gtgactataa attatttaaa cgtaagaaat
     2041 gaaccaactg ctgaaagtag tatagccttt gttgctaaaa aagatgataa agttttgatt
     2101 aaagactctt ctaatggatg gtataaaata aaagctgaat ctggacaaga aggttgggct
     2161 tcatcaaaat atatagcaaa attaaatggt gactctttaa gaacatctac aaataaagaa
     2221 aaacaagtta cttcaaatag tttaaatatg agaaatggag caggtacaag ttatagagta
     2281 ataactgtac taaaaaaagg tcaaaaagta gaagtaatat cagagagtaa tgggtggtct
     2341 aaaatcaaat atgatggaag attagggtat gtatctagtt cttatttagg agatgtttca
     2401 aattcaacta ataaatcaaa aacaaaacaa gtgaatacaa cttcactaaa tgtgagaagt
     2461 ggaccaaata caagttatgg cttgttaggt aagttgtcaa aaggaagtaa agtagaagta
     2521 atatcagaaa gtaatggatg gtccaaaata aagtataatg gaaaagatgc atatgtatct
     2581 agtatgtact tatcagatgt aagtcaaagt aattcagacg attctagtca aagcaatgat
     2641 aaaaaaaata ctgataagtt tgtaaataca gcttctttaa acgtaagaag tggaccaggt
     2701 tctacatata gcaagttggg aaaggtttat aaaggaagta aggtaactgt gctatcagaa
     2761 agtagtggat gggctaagat taattttaat aataaagaag cctttgtagt aggtaattat
     2821 ttatctactt cagcagatgc atcaaataat aactcaaata gtaactctga tagcagttct
     2881 agtaataatg gtaataattc atcatcaggt caagtaaatg gtatgtcagg tataagtgga
     2941 gctaaaattg attataaatc tttgaattat actttggcat ctcatataag taaacaagtt
     3001 gagaaagcag catcaggagg aaatgtgata gcaccaagta ataggaaaag caccccaagt
     3061 cctgaattta gtactttttc agcccaaaga acaagctcat ttgtaaatgc aagttcaagt
     3121 gatatagaat attatttaaa tcctaaaaat tttataaata ctactaaagg tatgatgcag
     3181 tttttaaaga ttaacagtta tagaggtggt atttcagaat caagtcttaa ctcgtatctt
     3241 aatggtttat cttctagtgt atttaaaaac cagggagcaa catttataaa tgctgcaaag
     3301 aagtataata tagatgttgt atatctagta tctcatgcta tgtgggaaac tgcttatggt
     3361 aagtctacac ttgctcaagg tcagacatta acatcttata agggtcaacc tcttagtaaa
     3421 ccagttaaag tatacaattt ttttgggata ggagcgatag ataaaagtgc taatgtttca
     3481 ggtgcagagg cagcgtattc caatggttgg actagtgtag aagctacaat agatggatct
     3541 gcaaagtgga tatcacaaaa ttacataaac agttctaagt acaatcagaa tactatctac
     3601 aagatgaagt ggaattatga ttatacatgg catcaatatg caactgatgt aaactgggct
     3661 aatgggattt ctggaattat ggagaattta attggtcttt atggaggagg aagtagtttg
     3721 gtttttgaag ttcctcaata taagtaatat atgaataaaa aatatagact atgggtagtt
     3781 ttcattttat ttaaattatc tatagtcttt ttgtatataa tttacatgct gtaaatttaa
     3841 tgttaacaaa atttttatgc tataatatta attctaagca aatataagtg agtaatagat
     3901 agaaatagat aaaaagtggt aataatatat atagataatt ttgagaaagg aggatataga
     3961 tggaaagtat taaggaatat ttggataagt tagaaattaa taatagtggt cttggaaagc
     4021 aacttaaaga agtttacata aatagagtag tttattttaa ggaagataag atagtttatt
     4081 tttatctgac ttctaaggat attgtttctc atgagctttt agataaattt aaagaagaat
     4141 tgatgtataa actcgattat tttaaagata tgaggatgaa gataagattt actggtcttg
     4201 aaagaaaatc caataaagat gttataaaaa aatattggaa taatatattg tatatattaa
     4261 agtatctttg tccatctatt gcaggatggt ataaacaggt agaatttctt tgtttagagg
     4321 aagaattaaa aataaaactt ccaaaaggca tattttatga gcgattaatg aaaaaaaatg
     4381 taacctatgt acttaaaacc gtgcttagtg aagaactggg attagattta aatataacaa
     4441 tagaaaaagc ggttgatgaa aagataaata aagagagact cataagaatc aatgatagag
     4501 aaatggaaga aaaaattaga gctttagaaa ttggaaaagt taatagctgt gaagaaagtg
     4561 aagaggaagg ttacgtcatt aagtctgaag tagatgaaga attaatctat ggagataatg
     4621 caaatgctat gattgaaaat atagttgaat taaatgcatc ttctggaact gttgcagttg
     4681 ttggagatat atttgatgtt gatactaaag agcttaaaaa tggaaaaata cttatgatag
     4741 catcaattac agattatact agttcaataa gttgtaaact ttttttaaca gatacaaata
     4801 aagatggagt acttgaaaat gttaaaaaag gagcatactt aaaaatcaag ggtgacatag
     4861 tttatgatac atatcaaaga gaaattagta tgatgattag tggtataaga aaagaaacta
     4921 gaaaagagag agaagataaa tcagaggaaa aaagggtaga actacatgca catactcaaa
     4981 tgtcttctat ggatgctatt tgttctgtta aaaagcttgt agaacgtgcg gctaaatggg
     5041 gacatcctgc tattgctata acagaccatg gagttgtaca aggatttcca gatgccatga
     5101 atgcaggtaa gtcaaataat ataaaaatac tttatggagt agaagggtac ttggttgaag
     5161 aggattctct tattatagag gatgcaaatg ataaagaact ttctcagaca tttgttgtat
     5221 ttgacataga gacaactggt ttttctaata caaatgataa aataactgaa attggtgctg
     5281 taaaaataga aaactttaaa attgtagata gatttagtga attaataaac cctgaaaaag
     5341 atatttctta taagatacag gaattgacgg gaataactaa tgagctaatt aaagataagc
     5401 cgaccattga agaagttctt cctaagttta tggaatttgt tggagatagt gtattagtag
     5461 cacataatgc ggaatttgat actggattta tatcgcaaaa atgtagggaa caaggtttgt
     5521 tatataataa caaaaaagta gatacactta tgctagcaag agtaatgtta ccaaacttaa
     5581 aaagacatag actaaatgtc gttgcaaaag aacttggtat tcctctttta aatcaccata
     5641 gagcagtgga tgatgctgag gctacagcac ttatatttaa taaatttttg cagatgctta
     5701 cggaaaaagg tgcaaaaaca ttaagtgatg taaacaatat acttggaaag attgattata
     5761 caaaacttag cacaaatcat ataaccttga tagcaaaaaa ttctgtaggt ataaaaaatt
     5821 tatataaaat aatttcagat gcacatgtaa atcatttttt tagagcacca agaatcctta
     5881 gaagtgtgtt aaatgaatat aaagaaggat taataattgg ttcggcctgt gaagctggag
     5941 tggtttttca agctgtaaag aaaaatgtat ctgatgagga aatgaaaaaa ataatagatt
     6001 tatacgatta tattgaagta atgcctatag ataataatag gtttatgatt gataaaggag
     6061 aagtaaagga cgaagaagag ttaagggaat tgaataggaa attaattgat acagctaaaa
     6121 aatttaataa aattccagta gctactgggg atgttcattt tttagataaa catgaagcta
     6181 tcttaagaaa agttcttaaa tattctcaag gttttaaagt agatgaagaa gaaacttatt
     6241 tacattttag aacaacagat gaaatgttgg aagagtttag ttatcttgga gaagaattgg
     6301 catatgaagt tgtagttgaa aatagtaatc tgattgccga tatggttgaa gatataaaac
     6361 ctataccaga tgatacttat cctccaatta tagagggttc agatgtggag ttaagagaaa
     6421 tgtgttacaa aaaagcaaaa cgaatctatg gagacccaat accagaaata gttcaaaaaa
     6481 gactggatag agaattaaat tcaataataa gcaatgggta tgcagttatg tatattatag
     6541 ctcaaaagct agttgcaaaa tctctttcag atgggtattt agtaggttca agaggttcag
     6601 ttggttcatc ttttgcagct actatgagtg atataacaga agttaatcct cttccagcac
     6661 attatatttg tgaaaatgaa gactgtaaat attcattctt ttatgaaata ggtgaatggg
     6721 gttcaggtgt tgatttacca gacaaagact gtccaaagtg tggaagaaaa cttgccaaaa
     6781 acggtcatga tattccattt gaggttttct taggttttga aggtgataag gaaccagata
     6841 tagacttaaa tttctcagga aattatcagc caacgattca caaatacaca gaagaactat
     6901 ttggagaggg ctatgtatat agggctggaa caataggtac tgtagcagaa aaaacagctt
     6961 ttggatatgc aagaaaatat gtggaggaaa ataatataag tgtaccaaat gcagaagtac
     7021 ttaggctttc aaatggatgt actggagtaa aaagaacctc aggacagcat ccaggtggag
     7081 ttatggttat accagattat aaagatgtgt atgattttac acctatacag tatccagcaa
     7141 acgatacttc ttgtggtgtt ataactactc actttgatta tcattcaata agtggtagaa
     7201 tacttaaact tgatatactt ggacacgatg gtcctaccat tataaggatg cttgaggata
     7261 tgactggaat aaatataaca gaaattccgt tggatgataa agagactatg tctctattta
     7321 catctacaga agcattgggt gttacaccag aagaaataaa ctgtcctata ggttgccttg
     7381 ctgtaccaga gtttggaact aagtttgtac gacaaatgtt acttgacacc aaacctacta
     7441 catttgcaga acttgtacgt atatctggtc tttctcatgg gacagatgtt tgggtaaata
     7501 atgcacaaga cttagttaga gaagatatag ttggcttaaa agatgttata tctacacgag
     7561 atgacataat gaactattta atatttaaag gattacctcc caaaatgagt tttacaataa
     7621 tggagagcgt aagaaaaggt aaaggtctaa aaccagaaca cattgcggag atgaaaaaaa
     7681 ataatgttcc agaatggtat ataggctcat gtaaaaagat taagtatatg ttcccaaaag
     7741 cacatgctgt tgcttatgtt atgacatcat ttagaattgc atattgtaaa gttcactatc
     7801 cagaggcatt ttatgcgact tattttacta caaaagttga ggattttgat gcagatttaa
     7861 ttgttaaagg attagatgct ataaaatcaa aaataaatga aattgagtcg ctgggaaatg
     7921 atgcaaccac aaaagaaaaa ggtatgttga ctgttttaga agttgctctt gaaatgtatg
     7981 ctagaggaat aaaattatta ccagttgata tatataaatc agatgcgact gagtttataa
     8041 ttgtaggaga aaaaacatta cttccaccaa tggcagcaat acaaggtctg ggaggaaatg
     8101 cggctataaa catccaaact gaaagaaaaa atggtgaatt tatatcaaaa gaagatttaa
     8161 gaaagagaac aaaaatatca aaaacggtaa tagaaactct tactaatcat ggttcacttg
     8221 agaatatgag tgagagaaat caattgtcat tgttttaagt tagcccaaaa agttgcaaat
     8281 aaaagaattt tatgatatca tagtatagaa aatagtatac tttgcagaaa ctaagagtga
     8341 gaccgctgtt ctcactcttt tattttaaat atattattaa aaagctggtt taattttatt
     8401 aaatatattt tgtttaagat tatataaact ggtcatttac aattgaatag gaggaatttt
     8461 aatgaaaaaa aatttagaag ctacaatcga ggagattgta actaaaataa cagatgagca
     8521 tggatttgaa atggttgatg ttgaatatgt aaaagaagca ggagaatact acttaagagt
     8581 atacatagat aaagaagaag gaatatcttt aaatgaatgt gaattagtta gtagagaatt
     8641 aagtccaata ctagatgaaa aagaccctat aaaagagaat tactttttag aggtatcttc
     8701 tccagggctt gatagagcat taaaaaaaga cagagatttt gttagatatc aaggtagaga
     8761 tgttgattta aaattatata aaccattaaa tggatgtaaa caatttgaag gtgaacttgt
     8821 aggattaaca gaagataata atataaaaat cattgtaaat ggtaaggaaa ttgaatttaa
     8881 tagaaaagat gttgctattg tcagattagc aataaagttt tagtggtata ttaaataggg
     8941 aggatataaa aaatgaatca tgaatttatg gaagcattag atgaattagt agttgacaga
     9001 ggtatagata aagaaatact tatagatact atagaacaag ctcttttaac tgcatacaag
     9061 aaaaactttg gttcagcaca aaatgttaga gttgaatttg atagagacaa gggagatata
     9121 aaagtatttt ctcaaagagt agttgttgat gaatcagatt tatatgatac tttcttagaa
     9181 atagagttag cagatgctag agagataaat cctaattatg agttaggtga tattatagaa
     9241 catgaagtta cacctaaaaa ctttggaaga attgcagctc aaacagcaaa gcaagtagtt
     9301 gttcaaagaa taagagaagc tgagagagaa atagtgtata atgagtttat agaaaaagaa
     9361 aatgaaatag ttacaggaga ggttgctaga gcaaataaaa atgttgttta tgtaaacctt
     9421 gggagaatag aaggtataat gactcaaagt gagcaaatac catttgaaaa ttataaagca
     9481 ggtcaaaaaa taaaattcta tatacttgaa gttaaaaaaa ctaacaaagg acctcaaata
     9541 gttgtatcaa gaagtcatcc aggtttagtg aagagattgt ttgaagaaga agttcctgaa
     9601 atatatgaag gaatagttca aataaaatct gtagcaaggg aagctgggtc aagaactaaa
     9661 atggcagtaa gatctataga tgaaaaaata gacccaattg gagcttgtgt tggaccaaaa
     9721 ggacttagag taaaaaatat agtggatgaa cttggcgatg agaaaataga tataataaaa
     9781 tatagtgaag acccagcaga gtttatatca gcagcactta gcccatcaaa agttgttaga
     9841 gtagatatag atgaagatga aaagtctgcc ttagtaatcg ttccagatta tcagttatcg
     9901 cttgcaatag gtaaagaagg tcaaaatgca agactagcag caaaattgac taactggaaa
     9961 atagatatta agagcgaatc tcaagcagaa caagaaatgt taaatcttga aaattccaaa
    10021 aaaatagaag ctgaggatgt tgaagctgaa tttatcgaac aagaagagtt agatacttca
    10081 gatgataatt ttagtgatga agagtaagga gggatgattt tgaaaaaagt aaaaaaagtg
    10141 cctcaaagaa aatgcatagc atgtcaagat agagactcta aaaaagagct tataagaata
    10201 gttaaaaata aagaaggaaa aatattttta gacccaacag gaagagccaa tggaagagga
    10261 gcatatgtat gtaaaagctc tgaatgtcta aaaaaagcta taaagagtaa agcattaaac
    10321 aaagctttta agatagatgt tcctgatgaa gtctatgata atctacttat ggagttagaa
    10381 gaatatgaaa aataataaag aaaaagtact ttcgttctta gggctcgcaa ctcgtgcagg
    10441 gaaaatagtg tctggtgatg attcaacttt gctcgacctt aaaaaaggaa aagtaaattt
    10501 gattttaata gcagaagatg catcaaataa tactaaaaaa ctttttaaag ataaatcaac
    10561 ttttagaaat attccatatc tatttttttc aacaaaagag gaaataggat ttgcaatagg
    10621 aaaatctcca agagcagttg taggaataaa agatgaaaat ttttctaaaa agataattga
    10681 actaatagaa atttaaaata aaataggggg tgatcttgtg tcaaaaacaa gagtatacca
    10741 aatagcagaa gaattaaata tatcaaatga agagcttata aataagttag ctgaattaga
    10801 tataaatgta actgacaaag attcagtatt agaaggtgat gagttagaat tagcacttga
    10861 aatgttaggt gaagatttat ctcaagaaaa tggaaatatt atagaaatag atggaaagtt
    10921 gacagtacaa gtattagcaa caaaattaga taaatctcca tcagaaataa ttatgaagct
    10981 tatgaaaatg ggaactatgg caacaataaa tcaagagata agttttgaga ttgctgcttt
    11041 ggctgccaaa gactatggat ttgaattaac agtagctgaa agtgatgata cagaagcttt
    11101 agaaatagaa gctttaatgg aaattgaaga agataaagaa gaggatttaa aacctagacc
    11161 accagttgtt acagttatgg gacatgttga ccatggtaag acatctttac tagatgcaat
    11221 aagaaaaact gatgtaatct caggtgaagc tggtggaata actcagcata taggtgcttc
    11281 agaggttaaa atcaatggac acaaaatagt atttttagat acgccaggac atgaggcttt
    11341 cacatcaatg agagcaagag gagcacaagt tacagatata gcaatattag tagttgcagc
    11401 ggatgatggt ataatgcctc aaacagttga agctataaac catgctaagg cagcaggtgt
    11461 acctttaata gttgctatca ataaaataga taaaccaggt gcaaacccag ataaagttaa
    11521 acaagaatta gcagaccaag gattattagt tgaagactgg ggtggagaag taatagcagt
    11581 tccagtatca gctaagaaaa aagaaggaat agatacactt ttagaaatgg tattattggt
    11641 tgctgaaatg gaagagttaa gagctaatcc aaataaaaga gcagtaggaa ctgttataga
    11701 agctgagctt gataaaggaa gaggaccagt tgcaacagta cttgttcaag gtggtacttt
    11761 aacagtaggt gacccaatcg ttgcaggtgt tgcatgtggt aaagttagag caatgataaa
    11821 tgcaaaaggt aagagagtaa aaacagcagg accatctaca gcagttgaga tattaggtct
    11881 atcagaagtt ccacaaggag gagaccaatt tgtcgaagtt ccaactgata agattgctag
    11941 aagtgtagca gcaagaagac aacaaatagt tagagatgaa atgttaaaat caactcaaag
    12001 attatcacta gatgctttat ttagtcaaat gagtgaaggt tctataaaag accttaatat
    12061 agttataaaa gcagatgtac aaggttcagt acaggcagtt aaacaatctt tagaaaaatt
    12121 atcaaatgaa gaagttcaag ttaaagtaat acatggtggt gttggagctg taacagaatc
    12181 agatatatta cttgcagcag cttctaacgc aataataata ggattcaatg taagaccagt
    12241 tccaggtgca gaatctctag gagaaaaaga aaatgttgat ataagaacat atactataat
    12301 atacaaggca atagaagata tacaagctgc tatgactggt atgttagacc ctgaatatgt
    12361 tgatgaagaa acaggaaaag ctgaaataag agaaatatat aaaatatctg gtgttggaac
    12421 agtagctgga tgttatgtga ctaatggtaa gatatttaga aattgtaaag taagattagt
    12481 cagagatagc ataataatac atgaaggtga gcttgcagca cttaagagat ttaaagatga
    12541 tgtaaaagaa gttaattctg gatacgaatg tggtatgagt tttgtaaatt ataacgacat
    12601 aaaagaaggc gatatagtag aagcttatat aactaaagaa gtagaaagaa aattataaat
    12661 tcgtatcaaa gaaaatcagt tagtaaagaa ggtcgatggt atggcatcat ataatagaac
    12721 aagaaggata tcagaagaaa taagaaaagt agtaagtact atgcttataa atggagtaaa
    12781 agaccctaga ataacatcta tggtgagtgt aactgatgta gaagttacaa atgacctaag
    12841 atatgcttat gtatatgtaa gtattctagg tggagatgag gaatccacac taacaggtct
    12901 taaaagtgct ggaggatata taagaagaga agtaggaaaa aatataaaac ttagatatat
    12961 tcctgagata gtatttaaaa ttgatgattc aatagaaaaa ggaatgtata tggatagcct
    13021 tataaaaaga gttaatgaaa aaaatgctca acaaaatgag gatgaaaatt atgatgaata
    13081 atatggatag tattataaac tatatttatg agggtgacta ttttatagtt acctctcata
    13141 tcagtccaga tggagataat attggctcta cactttcaat gtattataca ttgaagaatt
    13201 taggaaaaaa tgtatattat gtacttgatg atgaagcacc attaaatcta ggatttttgg
    13261 ttgaaggtgt aaaaatctat aaatctaatg aatttaatat gaagaactat tctataattg
    13321 cacttgattg tggagataag atgagaatat gtgtgagtga tgaaatcaaa aataatgcat
    13381 caaaattaat ttgtattgac catcatgcta gtaatgattc atatggagat ttaaattatg
    13441 tagatattga tgcatcttct acatgtgaac tagtttataa tttattggtt agattccagc
    13501 aaataaaaga tattaatatt atcaatgaag atatagcaac atgtttatat acaggtcttg
    13561 taactgatac tggaaacttt tcatattcaa atgcacatgc aagtagtttt gaaatggcaa
    13621 aaaatttact tgttttaggt gcacaaaaaa atactataat acaaaatata tatcaaagta
    13681 attcatatga ttattataaa ttattaggag aagctctaaa agctttggag atatttaatt
    13741 caaaggtatc tagcatagtt ttaactcaag acatgatgaa tagaaataat attagcttta
    13801 atgatgttga tggaataaca acatatacaa gagatataaa aggtattgaa gttggaattt
    13861 tatttaaaga gaaaaaacaa aatgaaatta aagtaagttt taggtcaaaa aattatattg
    13921 atgtaagtga aatagccaag ttatttggcg gtggtggtca tgtaagggct gctggatgta
    13981 ctattagaga tagtattgat aatgcaaaaa aaatggtact agaggcagtg ttaaaatcaa
    14041 tttaaggtga cagtaaaatg aataagatta taagtatatt gaaacctaca ggtatgacat
    14101 ctcatgatgt tgtaagtaga gtgagaaaga ttttaaatat aaaaaaagtc ggtcatacag
    14161 gtactcttga cccagatgct tcaggtgttt taccaatctg tatagggaaa gctacaaagg
    14221 tatgtgaagt tattttaaac aaagataaat cgtatatatg tgagcttacc ttaggtataa
    14281 gtacagatac ttatgatgcc tcaggtgaaa ttctaaaaaa agttgatgat tttaaattta
    14341 gtaatgaaga gataaaaaga gcttttgata cacaaagagg agagataaat caacttcctc
    14401 caatttattc ggctttaaag gtaaatggaa agagaatgtg tgatttagta agaagtggta
    14461 gacaatctga aatcacttta aaaacaagac gagtaaatat aaaaaacata aaaatactaa
    14521 gtataaaagg taataaagta atgttttatg ttgagtgttc taaagggact tatgtgagaa
    14581 gtatttgcca tgatatagga gaatatctag gttgtggagc tcatatgtcg tttttgaata
    14641 gaacatcttc tggtaaattt gatttagaca attcaataac attagaagaa ttagaattat
    14701 tttatgaaaa taaaacttta gacaaatact tatatgatat agattatgta cttgattcat
    14761 ttaattatgt tgtattaaac tctaatgcta taaaatatta tagcaatggt ggttcaatag
    14821 atgacaaaag gtttttaaaa aataatttca ataaagatga tgaatttgta agagtataca
    14881 gtacagataa tttcttagga ttaggaaagt tgtcaaaaca caataatata ataagtgtta
    14941 aaagtgataa gatgttcata taaataatgt atttaaaaaa caacaaaaga gatagtacta
    15001 taataacttc tatagtctat ctcttttact tatgctataa tagtttgtga ataagttaag
    15061 agtaaattat attttagcgg ggaacattta ttatggagat tataaaatct ataaaagaaa
    15121 tagcaaacat aaaagaaagt gtcattacca taggaaattt tgatggtgta cacaaaggac
    15181 atcaagttct tataggaaaa acagttgaac atgcaaaaaa agaaaatata cagagtattg
    15241 tatttacatt tgcaaatcat cctgtaaatt actttagacc aaactcaaca aaaaatatta
    15301 taagcaatga tgataaaata aaattattag aagatttggg aatagatata gttgtaatca
    15361 taccatttga tgagtatatg actaaaatac ctgcaaagga ttttgtagat gagatactag
    15421 taaaaaaatt aaaagctaaa aagatagtaa ttggacatga ctttacattt gcaagggcaa
    15481 aagaaggcaa tgttaatcta ttaaaaagct tagaacatga atttggtttt gaggtagaag
    15541 taataaaacc aatcaaaatc aatgatgtaa gagtgagtag tacttatatt agaagtttag
    15601 tatcccaggg tgatatggct agtgtcaagg aatatttggg aagaaattac aagttagaag
    15661 gttgcgttat acattctaaa catcttggaa gaactatagg attcccaaca gcaaatattg
    15721 accttaagaa taatatgctc gttccaaaga gaggtattta tgcttccatt gtacatattg
    15781 gagatgagac ttattttggt gctacaaatg taggctataa cccaacagtt aatggaaaaa
    15841 ctttgtctat tgaaacaaat attttagagt ttgatagaga tatttatgga gaaaatataa
    15901 ttgttgaatt tttggaaaga ataagagatg aaagaaagtt taattcaata gatgacttaa
    15961 aaaatcaatt gtataatgat acaaattatg tgtatgaaaa ctatgtttgc aaaaacaagt
    16021 aatgtatgat aaaatgatta aggaaaataa ccattactcg gcatttgaat actccaatca
    16081 atgcttagta ataggcgttt ctaaaaaaat acggaggtaa tctaaatgat aaacaaatca
    16141 gaaataataa aagaatatgg aagagctgaa ggagatactg gttctccaga agtacaaata
    16201 gctttattaa cagctagaat aaacgagtta aatggacatt taaaaactca taagaaagac
    16261 caccattcaa gaagaggtct attaaaaatg gttggtagaa gaagaaactt attagcttac
    16321 ttaaaggaaa aagatcttga aggatataga gcattaatag ctaaattagg attaagaaag
    16381 taatttcatt ctttataaaa aagcaggtat agtgtatacc tgctttttta tagttaattc
    16441 attataaagt aaaatagtta ataataaaag tagtttatat gttataaaaa attataaaat
    16501 gaataatatt gggtaagaat attaaaatag tatacaaata cataatcaat ttaaaaggaa
    16561 agataggaca aatatagaaa ttttataaca ggataattag ttagaataag gaggatatta
    16621 ttttgaaaat aaagttagta tgtgatagtt tatgcgatat tccagatgaa atatcagaaa
    16681 aagattatat agagatagtt ccacttacag ttatttttaa tgatagggaa tatatagaag
    16741 gagtagatat aaagaaagaa gagttttata aaaaagtaaa agaaattaaa caaataccta
    16801 aaacttcaca agctacatat atggagttta aagaagtatt tgataagttc atagcagaag
    16861 gttatcatat aatctgtatg acaggggctg caaacgcatc aggaactttt caaagtgcta
    16921 tgatagctaa aaatgatgta gatgaaaatg aaaaaataca tatatttgat actagaaatt
    16981 tatctctagg tagtggacaa tatgttataa aggcatgtga acttcttgaa gaaggactgg
    17041 gatttgaaaa aattatagat gaattagaaa atactcgaag tagtgtaaga ttactttttg
    17101 caccatatac acttgatttt ttaaagcaga gtggaagagt tccagttgca actgctttga
    17161 taggaaatat gttaaatata aagcctatat ttttctttga taatggggaa gctaagttgg
    17221 taaataaggt tagaggtata aaaaatatag caagtaaatt ggtcgatata attttagaaa
    17281 tgaatgaagg gtctttagaa ggaaaaatca tcacaatagg ttgtggagat aatttacatg
    17341 attgtgaaat attaaaagat gaagtaaata aaagaataaa agcaagaagc gtattattta
    17401 ctcgaggagg agtttctatt tgctctcata cagggccaga tatattggct ataagttgtt
    17461 ctaattagta gtaatataag gtttttgcat atatatgtga agataatttt atattgttaa
    17521 tttatagtat ttttgataat atagtaaata gagtgatata cgtgtttttt aataagagga
    17581 ggacaagcat taatgtttga acataaaata tttaaaatgg attttgcagg aagagaactt
    17641 tctgtagaaa taggaaagat ttgtgaaatg gctagtggta gttgtatagt tcgatacagt
    17701 gacagtatgg taatggtaaa tacaactaaa tcagccaaac ctagagacgg aatagacttt
    17761 tttcctttaa gtgtggatta tgaagaaaaa ttatactctg taggtaagat acctggaggt
    17821 tttttaaaga gagaaggtaa gccttcagaa aaagctatac ttacatcaag attgatagat
    17881 agaccaataa gacctttatt cccaaaagga tttagaaatg atgttcaggt agttgcaaca
    17941 gttctatcag tagaccaaga ttgcacacca gatatagtag caatgatagg ttcttcaata
    18001 gccctttcta tatcagacat accatttaat ggaccaacag gttcagtatg tattggcctt
    18061 gtagatggtg catttgttgt aaatccaaac gcagagcaaa gagaaaaaag ttcaatgcat
    18121 ctagttgttt caggtacaaa ggaagcaata atgatggttg aagcaggagc tgacgaagtt
    18181 ccagatgagg taatgcttga tgctatttta tttgctcacc aagaaataaa aaaaatagtt
    18241 gagtttatag aaggtatagt tgcagaagtt ggaaaagaaa aaatgcctgt tgaattatac
    18301 catgcaggag aagaaataac tcaattggtt cgtgaatttg caactgataa gatgaaaaaa
    18361 gcagttcaga cttttgaaaa gttagagaga atggaaaata tggatagagt taaagaagaa
    18421 actttagctc actttgaaga gactttagaa gattttgaag attttgttgg agatatagaa
    18481 gaagtattac aagatataat aaaagaagaa gtaagaaaac ttatagtaca tgaaaatgta
    18541 agaccagata atagaaaact tgaagaaata agacctatat ggtgtgaaac tggcatgata
    18601 cctagagctc atggttcagc catatttact agaggacaaa ctcaagtact taatgttgct
    18661 actttaggtg ctttaggaga tgttcaaaaa ttagatgggt tagatgaaga agaaaacaag
    18721 agatatatgc atcattataa tttccctgca tatagtgttg gagaagctag accatcaaga
    18781 ggaccaggaa gaagagaaat aggacatggt gctctagcag aaagagcttt attaccagta
    18841 ataccatctc aagaagaatt tccttatgct attagattag tttctgaagt attaagttca
    18901 aatggttcta catctcaagc aagtgtatgt ggctcaacat tatctttact tgatgcaggt
    18961 gtacctataa aagatatggt tgcaggtata gcaatgggac ttataaagca tgatggtaag
    19021 gttgcagtgc tttcagatat acaaggtatg gaagaccatt taggtgatat ggactttaaa
    19081 gtagctggaa cagagtatgg tataacagca atacaaatgg atataaaaat tgatggtata
    19141 gataaagaaa ttctacaacg tgctttaaaa caagctaaag aaggtagaat ccatatacta
    19201 ggagagatga gaaaaactat atctcagcca aaaccagaac tttcaccata tgcacctaag
    19261 attgttaaaa tgcaaataaa tcctgacaag ataaaagatg taataggacc tggtggaaag
    19321 ataataacta agataataga cgaaactgga gttaagatag atattgaaca aactggggaa
    19381 gtatttatat caggtattga gattgatatg attaagaaag ctcaagaact tataaataat
    19441 atagtagtag aaccagaagt aggaaaaact tataaaggta aagtaagtag aataatgaac
    19501 tttggagcat ttgttgagat acttccagga aaagaaggat tacttcatat atctcatata
    19561 gctcatgaaa gagttgctaa agttgaagat gtattgaata taggggatga agttgaagtt
    19621 aaagttacag agattgatga aaaaggaaga gttaatttat caagaaaagt tcttttacca
    19681 aaaccagagc ataaaaataa ataatttatt aaataataaa aagcaaagtc ttaggatttt
    19741 gctttttatt atttggtgca taaacagagc ttatttttaa tagtattaaa taagaaacaa
    19801 tttgtacata attaggggga gttttaatga taatgatggt acttaataag agtaagctca
    19861 aaaaaatcat aatactaatt ttagtagtgt tattagtatt atcaggaggg gtaatggtat
    19921 taaagttatt taacaacaag ccagtattta atttatttaa tggtgtagat ttaccatatg
    19981 aaagaggtac aaaggatgaa agtggatacg ttgcattaac ctgtaatata gaccttggat
    20041 gggaaacaga gtacgtagaa tccattttag aaacacttaa aaaagaaaat gtaaagatta
    20101 catttaatgt aaccggaaaa tgggcagaaa agaataagga cgaattatta aagataaaaa
    20161 aacaaggaca tgaaataggt aatcatggat acaaacattt agattactct acattatcct
    20221 atgaagacaa ttatgagcaa atagagacct ctaaaaagat aattgaagaa attataggtg
    20281 aaaaaactaa attttttcaa gcaccagcag gttcttttgg tccagaaaca gtaaaagctg
    20341 ctaaagcatt agggtatact tctatcaaat gggatgccga tactatagac tggaaataca
    20401 aagaccaacc agaggtaatc attgatagaa tgaagaaaaa agatattaaa gatagtagta
    20461 taatcttaat gcacccaacc aatgcaacga caaaatgtat agatgatatt atagctattg
    20521 taagagaaaa aggactaaaa ccaggaaagc ttagtgatgt atttaagtag acaaagtata
    20581 aatatttggt taagattgta taagttgtag ttgaattaat taaaagactg acttataatg
    20641 taatacatat aaaaaataaa tataattaaa acatagtgtt ttcaataatc caatatgaaa
    20701 caaagaataa attgttagga gaatgtaatg tataagacaa aaatactgga aaatgggctt
    20761 acaataattg gtgaagaaat accatatcta aagtcaataa cattaggtat ttggataaat
    20821 gcaggctcta ggatagaaga agcacaggtg agtggaactt ctcattttat agagcatatg
    20881 atgtttaaag gaaccaaaaa cagaacatca aaagagattg ctagctcaat agataatttg
    20941 ggtggtcaac taaatgcatt tacaagtaaa gaatgtacat gttattatgt aaaactaata
    21001 gatgagcata tagatatagg aattgatgta ttaagtgata tgatactaaa ttctaaattt
    21061 gataaaaatg atatcgataa ggaaagactt ataatattgg aagaacttaa gatgtatgaa
    21121 gattctccag atgacttatc ttatgattta ttagtggaaa atatatatgc taatgatgga
    21181 ttaggaatga atataattgg gacaaaagaa tctctataca atataactag agagtctatg
    21241 ttagaatact taaataagta ttatattcca aataacgctg ttatttctat agctggaaac
    21301 tttaactttg atgatatggt agagaaaatt aaatcaaaat ttggacactg ggaaaagaaa
    21361 aatttgagta tagacataag tgaggctaag tttaatcctt gctttatatc aaaaaataaa
    21421 gatactgaac aggtgaactt agctatgtgc ctaaaaggta ttccttttga aaatgatgaa
    21481 gaagtctact caatggcagt ggtaaataat atttttggtg gaagtataag ctcaaggctt
    21541 tttcagaaaa taagggaaga aaaaggttta gtatattcaa tatactcatc acagacatta
    21601 tatagaaaat gtggtgaatt aggtatattt gcaagtatga gtacagaaaa tttacaagat
    21661 gtgtataatt tagtaaaaaa agaaattgaa aatataagag aaaactatct taccgaagaa
    21721 gaaatatctg aaagtaaaga acagttaaaa ggcaattata tattggattt ggaaagtact
    21781 agcagtagaa tgatgtctac tggtaaatct atgttactta gtaaaaaagt aaaaactaca
    21841 gatgaaatac ttgaatgtat aaataatgtt gatattaatt cagtaaagaa agttgttgat
    21901 aaggttttca atgtcgagaa tattggtaca tgtatagttg gaagagatgt ggaaaaaatt
    21961 ctacacttga attaatattg taaaaagtaa atctctggag gtataaaata tgaatttatc
    22021 tgaaatagca ggtaaggaaa tagttaactt ggtcacagga gaaagattgg gggtcattgg
    22081 agaatgtgac cttatactag atgaaactac aggcggtata ttagcgcttc taattccaaa
    22141 agaaaaagga ttttttgcca gaagaaaaga taagtcattt ttagaagtac catggagaaa
    22201 tgtaaaaaaa ataggtaatg acatgataat tatagaatat gagggatata tttaggagga
    22261 aaaaatgagt attttagtgc aaaagtttgg tgggacatca gtagaatcat atgaaaaaat
    22321 gaatgaagta tgtaagatag taaaagcata caaaaaaaat gatgaagaat tacaattagt
    22381 actagtagtt tcagcaatgg gaagaaaagg agctccatac gctacagata cacttataaa
    22441 tttatgtagt gcagtaaatg atgagccaag caaaagagaa cttgatttaa taatgtcttg
    22501 tggggaaata atatcaggaa caattcttgc taatttattg aatgcacagg gtatagattc
    22561 tgttttcttt actggtcagc aagcaggtat aattacaagt gatgaatatt ctaatgcaaa
    22621 gataaagtat ataaatccta aaaagataaa aagagcttta gatgatggga aggttgtagt
    22681 tatagctgga ttccaggggg taacagatga tggagaaata actacccttg gaagaggagg
    22741 aagcgataca tcagcagttg ctattggtaa agctttagaa tgtgaaacag ttgaaattta
    22801 cactgatgtg gatggtataa tgactgcaga ccctagggtg gaaccaaacg ctaaagtatt
    22861 gagttttata gattatgagg aagtattcca aatggctgac aaaggtgcaa aggtaataca
    22921 tccaagagca gtgcaattag ctaaaagtgg aaatataact ttggctataa aaaatacaat
    22981 gaacccaact tttgaaggta caaaaatagg ttctttatgt agacacttag aagataatat
    23041 agaatatgaa caagaaagag attttaaagt tgctgttgca aataaagata gtgtagcaca
    23101 agttaagatt aagtcagcag aagaagtgtt tacagaagta ttaaatgaga tagaaaagaa
    23161 atttataact atagatatga taaatttctt catatcagaa aaagcatttg ttgtagaaga
    23221 tgctgatata aaatcattga aggaaatact agataaattt gaattggatt atgaagtaaa
    23281 tagagactgt gctaaggtaa cattgatatg ttcaagaatt gctgatgaaa tgtctggtat
    23341 catgtcaaag gtagttagag gattatcaaa agcaggggta tctcttttac aaacatcaga
    23401 ctcaaatatg actatatctt gtttagttag tgaagaagat atgcatacag cagtacatgc
    23461 tatacaccaa caattttatt taaaataaac aatataatac aattattttt taatcaaatt
    23521 tgataatttc atatatatct taatatattt gatttatttg gtaaaactaa attaaatatg
    23581 attttgatag gagttttttt tatgaaagat tatagagaag ataatgaaag atttgataaa
    23641 gataattgta gtgaagaatc tagtagtgaa gagagagaat gtataaagca atttggtacc
    23701 aatgaaatgc cacctcaacc tcctaaggat attcaatgta taactataat tggagaaatt
    23761 gagggacatt ttataggaaa tcctcaaaaa aaagctacaa agtatgaaca tataattcca
    23821 atgctgtact caattgagga aagtaatgat gttaaaggag tattagttgt tttaaacact
    23881 gttggaggag atattgaagc aggtttagct attgcagaac ttttaaacag tacatctaaa
    23941 aaagtagtta ctcttgtttt aggaggaagt catagtatag gagttcctct tgctacagct
    24001 ggagattact catttatagc accaacagca accatgatta tacatccagt gagaactact
    24061 ggtcttgtaa ttggcataaa tgagactttt gaatatttta aaaagatgca agatagaata
    24121 attcaattta taataagaac atcaaatatc aaaaaagatg tacttgaaaa acttatgcat
    24181 gaaaaagatg aacttgtaag tgatgttggt agtgtattaa taggaaaaga agctgtggat
    24241 tatggtctta tagatgaagt tggaggacta aaagaagcac ttaaaaaatt aagagagctt
    24301 ataaaagaat ctgaggaaga aaaaaataat gattaaaatt tgtttaaata ataaaattta
    24361 tgatataatg atgtaataaa gtaggagtgt tagtgttaag gcattagcac tttttgctgt
    24421 gaaggggtaa aacttgctaa aaataaggag tgatattaat ggccacgaaa aagaagaaaa
    24481 aaaagaaggt aaatacctta agttttaatg cagaatatca taatttaata acaatattta
    24541 taggtgtatt tttattatat agtttaaatt ctaattctat gggatggata cctgtgttaa
    24601 tgcaaaatct ttttaaggga ctatttggag ggctttcaat agcaatacca tttatagtaa
    24661 ttataacagg acttttagga ttttttgatg gaaatgaata tatatatagg ctaagaaaga
    24721 ctaaattata ctacataatt attttattta tatttgtatt ttatggatta ttaaatgcag
    24781 gtactcttcc tgtagatagc ccactaaaag gtaacatgtt tgatgatgtt atgaaattgg
    24841 gtgtaagtgg acaaggtagt ggcttgatag caacaactat tgcgtattat atgagtaaaa
    24901 tatttggtat agtaggtgga tggttaataa gtatctttgc acttatactt tctgtaatgt
    24961 ttatatttaa tatttctata aaagatatga tatcaaatgc aaaatcaaaa tctaaagcat
    25021 caaaagacag caatttaacg tttaaagata aaattgcaaa tatgaaaaaa tctgcaatag
    25081 atatgatgac tgatgaagta gatgatacta ctataaataa aaaaccaggt ttctttaaag
    25141 ggttaatgtc aaaaggtcgt aatactgatg aagaagatga atattttgaa gaagaaaata
    25201 gtgatggtgt agatgataag actataaaaa tagttggatt taataaggca gaagatgagt
    25261 atttagagat attagaagga actcaaagta tgccagagtt agatgtttta aaagaattac
    25321 aaaaagctac aaatgaaaat ccagttatag acactaaacc agaaaaaaaa gttgatatag
    25381 ctaagcctaa cttaaatata gaaaaaactc aacctatgag tattgtagca gagccagtta
    25441 atgaggatta ttcaaactat aagaagccta gcattgagct cttaaataaa gtaaataaga
    25501 agtctgatga aaatggtaaa aagaaagtgt taaaaaatgc ttctctttta gaaaagacac
    25561 tatcagattt tggagtggaa gcaaaaatta atcaagttac agttggacct actataacaa
    25621 ggtatgaaat acaaccaagt ccaggagtca aggtaagtaa aatcgtaaat ttaactgatg
    25681 atatagcttt aagtttagca gctaaaagta taagaattga agcaccaatt cctggtaaaa
    25741 gtgcaattgg aatagaagtt ccaaatgaag aagctcaaat ggttggtgtg agagaagttc
    25801 tagaaagtga agaatttaat aattttaact ctcctcttgc aatgggactt ggaaaagatg
    25861 tagcaggaaa aattataatt ggagatatag gtaagatgcc acacttacta atagctggtt
    25921 ctacaggttc aggaaagagt gtatgtgtaa atacattaat aagtagtatt ttatataagg
    25981 caaatcctga tgaagtaaaa ttactattaa tagacccaaa agtagttgaa cttgcaaatt
    26041 ataatgggat acctcatctg ttgataccag tagttactga ccctaaaaaa gctgcaaatg
    26101 ctttaaactg ggcagttaca gagatgaata gaaggtacaa gctatttgca gatgctcaag
    26161 taaaagatgt aacaagttat aatgagaaag cagaagaaaa acttcctaaa atagtaataa
    26221 taatagatga gttagcagat ttaatgatgg caagtgcaaa tgatgtagaa gattatattt
    26281 gtagactagc tcaaatggca agagctgctg gaatgcactt gattgtagca actcaaagac
    26341 catctgttga tgttataaca ggggtaataa aggctaatat accatctaga atagcatttg
    26401 cagtatcatc tcaaactgat tcaagaacaa tccttgatat gggtggtgca gagaagcttc
    26461 taggtaaagg tgatatgtta ttctacccac ttggtgcagc aaagccagtt agacttcaag
    26521 gtgcattcat atcagaaagt gagtcggaaa aagtaattga ttttgtgaaa agtcaggtta
    26581 aagatggaat aaaatatgaa gaagatataa ttgaaactat atctaaggtt aatacttcaa
    26641 agggtagcga tgaggatgag tttttgagtg aagcgataga atttgttgtg gaaagtggtc
    26701 aagcatctgc ctctatgtta cagagaagat ttaaaatagg atttaataga gcagctagac
    26761 ttatagactc tatggaagaa agaggaataa ttggagcaag tgagggaagt aaaccgagaa
    26821 aggtattaat aagcaaacag gatttgcaga atttagaagg tgaatagaat tgtcagttat
    26881 aaaaatagaa aaagcactta agctagacaa agtaatattt gtagatgtaa gaactgaagg
    26941 ggaatatgaa gaagaccata tattgaatgc aattaatatg cctcttttta aaaataatga
    27001 acataatgaa gttggaacaa tttataaaat gcagggaaaa catgaagcaa tacaaaaggg
    27061 gtttgactat gtatcttata aattaaagga tatatattta caagcagcag aacttgcttt
    27121 aaattatgat aatattgtca tatattgtgc aagaggtgga atgagaagtg gaagtatagt
    27181 aaatttatta tcatcattag gtgtaaatgt atatcaactt gaaggtggat ataaggctta
    27241 tagaaatttt gttttagagt atttaaggca tgtaatggat acaaaaaact ttgtatctgt
    27301 tcatggactt actggtacag gaaagactga tttactacat ttattagatg aaaaaggaat
    27361 agatgtacta gatttagaag gcatagctaa aaacagtggt tctacctttg gttttataac
    27421 gtttgataaa aaaccaccat ctcaaaagaa ctttgaaaca aaattatttg aaagtatatt
    27481 tttctcaaaa gagaattata tctttgtcga gagtgaaagt aaacgagttg gaagtgttac
    27541 aattccaaat gaaattttcg aggcaatgac acgagaagga catcatatat tattagaatg
    27601 tgatattgaa aatagagttg atagactttg tagagattat atttatgata aagatgaagg
    27661 taatctattg gttttaaaag aatgtataaa caaatttaga aaaagattgg gtcataaagt
    27721 agtagatgat tatattgatt tattagaatc aggtgaatat aaagaactcg taaaaagata
    27781 tcttttagaa tactacgacc cactttatat gcattcagta gagaaatata agtataataa
    27841 ggttataaac tttaatgata cagaagaagc tttagaagat gttatagact tatatgagag
    27901 tatattggaa ggagaaaatg aatgttaaaa atagcattag aatcattagg atgctcaaaa
    27961 aatttagtag atgcagaaat aatgatggga attttaaata acaaaggcta taaattaatt
    28021 ggagattttg aagaagctga tgtaatcata gtaaatacat gtggatttat agagtcagct
    28081 aaacaagaat ctatagatac gataataaac tttgccgaat taaaaaaaac tggcaattta
    28141 aagttgttga tagtaacagg gtgtttagcc caaagatatt ctgaagaatt aaaaactgaa
    28201 attcctgaaa tagatgctat agtaggtaca ggaagctatc aaaatataga taaaatactt
    28261 agagaattaa gtgaaatgca tcaaattgta agccttaatg atatagagtt tgtatttaat
    28321 gaagatttac caagatatct atctacacct agctatatgg catatttaaa aattggagaa
    28381 ggatgctcca ataattgtac ttattgtata ataccaaaac taagaggtaa atatagaagt
    28441 agaaaatttg aagatataat taaagaagct aagaaattag ctgaatctgg agtaaaagaa
    28501 cttgtagtta tagcacaaga tacgacaaag tatggttttg atttatatgg aaaagaaaga
    28561 ttatcagaac ttttagaaga acttgcaaag atagatggat ttaagtggat aagagttatg
    28621 tactcatatc cagaatctat aacagaagaa ttaatacaag ttataaagaa atatgataat
    28681 atatgtagtt actttgatat gccaatacaa catgcaagta acaatatttt aaaattaatg
    28741 aatagaaaaa ctactaaaga agatatatta aataaaatca atcttataag aagtaatata
    28801 ccagatgcta tacttagaac tactataata gtaggatttc ctggcgaaac agaagatgac
    28861 tttaaacaac ttgtggattt tgttgaagag gttaaatttg atagacttgg tgcatttgca
    28921 tattcaagag aagaagatac accagcagat agattgccaa accatataga tgaagacgta
    28981 aaaatacaaa gaagagatac tttaatgatg attcaacaaa aaatatctga agaacttaat
    29041 gacaaaaaga taggaaaaac ttatgaggtg ttaatagaag aacagataga agataatgta
    29101 tatacaggaa gaacacaagg tgatgcggaa gaaattgaca gtatagtgta tgtgaaaagt
    29161 gtagacaatc ttgaaatagg agaatttgta agtgttaaaa taaatgatgc aatggaatac
    29221 gatttaatgg gagatgtttt atatgaactt gcctaacaag ttaactttgt ttagaatatt
    29281 tttaatacca gtatttgtct taattatgtt gctcaatata ccaaataaat ttttaatagc
    29341 ttgtattatt tttataatag cttcaattac tgatgcttta gatggaaaaa tagctagaaa
    29401 atacaatcta gtcactgact ttggaaaatt tatggatcca ttagcagata agctattagt
    29461 tatttcagca cttacatgta tgatagaaga ccatcttgta agcagttgga tggtaattat
    29521 aatagtggct agagagctta cagttagcat attaagagct atagctgctg ctgatggaaa
    29581 agtaattgca gctggaaaca gtggaaaact taaaacgata actcaaatgg tatctatagt
    29641 gcttttattg ttaggtgctc agtttgcaaa tggattgata ttaaatattg gtgaaattct
    29701 cattcttata gctactctac ttacattata ttctggatgg gaatatttat ataaaaataa
    29761 agagctcttt atgtcttcta agtaaaaaat tatgctttaa taaataaaaa ttaacaactt
    29821 aaaattttaa aaatgtaaaa aagggtatac tattatagta tatctctttt cattttaaga
    29881 atattttctt ttgtgtatat aattattaat aatggtttat aaataaaatg taatgaataa
    29941 aaatataatc attagtagcg tttttaaatt gactaggttt gatttatgtt atataattaa
    30001 tatataacaa gagaacaaat gtttgtagat aaatgaaggg atggtataga gatgagtgta
    30061 gatcaagaaa aattaaaagc gttgaatgaa gctttaggta aaattgaaaa agattttggt
    30121 aaaggttcag taatgaaatt gggagaagca acatctatgt ctatagatgt tatatcaaca
    30181 ggagcgattg gtttagatat agctattggt ataggaggtc tacctagagg gagaatagtt
    30241 gaagtatatg gtccagaatc ttctggtaag actactgttg cacttagttg tgtagcatca
    30301 gctcaaaaag atggaggaat agctgcattt atagatgcag aacatgcact tgacccagta
    30361 tacgcaaaag ctttgggcgt ggatgttgat aacctaataa tatctcaacc agatacaggt
    30421 gaacaggctt tagagatagc agaggcattg ataagaagtg gagcgataga tataatagta
    30481 atagactcag tagcagcatt agttccaaag gctgaaatag atggagatat gggtgactct
    30541 cacgtagggt tacaagctag acttatgtcg caagctctta gaaagttaac tggttcaatt
    30601 aaaaaatcaa attgtgttgc tatatttata aaccagttaa gagagaaagt aggaataatg
    30661 tttggaaacc cagaaactac tactggagga cgtgcattaa aattctattc atcagttaga
    30721 ttggatgtta gaaaaataga cacaataaaa caaggagata aagttatagg tagtagaact
    30781 agagttaaag tcgttaaaaa taaagtagca cctccattta agcaagctga atttgatata
    30841 atgtatggag aagggatttc aaaaattgga gaccttctag atatagctgc tgatgtagat
    30901 atagtaaaaa aatcaggttc atggtatagt tacaatgata ctaaacttgg acaaggaaga
    30961 gaaaatgtta aaaaattctt ggaggataat ttagatttaa ctaatgaaat agatgagaaa
    31021 gttagagcat tttacaattt aaatgaagaa catgaagaag caggtaattc agtatcaaaa
    31081 gaaattgtag aagaataagt aaaaatacaa aaaaataact agtaattaaa gacatgccac
    31141 gctccctatt agcttgacac aatgttgaaa aaattataaa attaagtgag gataaaatat
    31201 ctaaatttaa ttttaattat taggaatatt ttttaatcat agtgatgaca ttttgggatt
    31261 attaacgaag gaggtggatg tcatagatag tgtagtaatg attgtaatag gtgcagctgt
    31321 tggtattata gctggatatt ttgttagaaa aaatatatct gaagcaaaaa ttggacaagc
    31381 tgaaaacttg gccaaagaaa taatagataa agcacaccac gactcagaaa cagtacaaaa
    31441 agaaaagtta ctagaagcta aagaagagat ccataagtgg agaacagaag ctgaaagaga
    31501 aaacagagaa agaagaacag aagtacaaaa gtatgaaaaa agagtagtac aaaaagaaga
    31561 agtattagat agaaaattac aaaatttaga atctaaagaa gtaaacctaa gtgaaaaatt
    31621 aaaggtagtg gaaaagaaag aagaagaagt tgaagtaata aaaactcaac agctagaaaa
    31681 attagaaagt atatcaggaa ttacttctga taaggcaaaa gaaatcatct taaccaatgc
    31741 agagagagat gtaagacgtg aaatgtctat aatgataaaa gagatagaaa gtcaagctaa
    31801 agaagaagct gataagaaat caagagaaat tataggatat gcaattcaaa aatgtgcagc
    31861 agatcacgta gccgaaacta ctgtcacagt agtaagcttg cctaatgatg aaatgaaagg
    31921 tagaataata ggtagagaag gtagaaatat aaggacttta gaaaccttaa caggtataga
    31981 ccttataata gatgacactc cagaagccgt aattttatca ggatttgatc caataagaag
    32041 agaaattgca agaattgctc tagaaaaatt aatagcagat ggaagaatac atccagctag
    32101 aattgaagaa atggttgaaa aggcgagaaa agaagttgac aatattataa aagaatatgg
    32161 tgaacaagct gcatttgaaa ctagtgtaca tggaattcat ccggaattaa taagattatt
    32221 aggtagactt aactatagaa ctagttatgg acaaaatgta cttaaacatt ctatagaagt
    32281 tgctcatata gctggtataa tggctgctga aataggagca gatattagat tagctaagag
    32341 agcaggttta ttgcatgata taggtaaggc tgtagaccat gaaatggaag gtacacatgt
    32401 tgaaataggt atggatttac ttagacgtta taaggaatct aaagaagtta tacatgccat
    32461 gagtacccat catggagatt atgaacctca aacagtagaa gctgtattag ttacagcagc
    32521 agatgcaata tcagctgcta gacctggagc tagaagagaa actttagaag catatataaa
    32581 gagacttgaa aaattagaag aaatagctaa ttcatatgaa ggtgtggaaa aatcatttgc
    32641 tatacaagct ggtagagaaa taagaataat ggtaaaacca gaagctataa atgatgaaga
    32701 aatacaccta ttggctagag acatgactaa gaaaatagag gatgaacttg aatatcctgg
    32761 acaaataaaa gtaagcataa taagagaaac aagagctata gaatatgcga agtaaaagaa
    32821 ataatatcta aataataaga aaatattttt agaaatttaa atttgccaca agatataata
    32881 tatcttgtgg tttttaaatt gtttaaattt aattttatat aatgtaaaat aatctaagtg
    32941 ctaaaagtgt tacttacaat aaattaatga aataaagatt tatatatgta ttgtttatat
    33001 aattatccaa atttgtttga tataatgaag ttgtaaaata aatatattac tacttggaat
    33061 gcttatactt aaataatatg aaaatacaat aaagctaaag tgaggtttaa agagagggta
    33121 cactatgaaa aaaaatacac ttttacatac aaatattatg gtttgcatta ttattactct
    33181 tggttttgtg gctacctcta taattggata ccaatctaat accaatattt ttaaaaatga
    33241 tattgaacat gtgtctacat tggctgctga aggtatttat tatcagatag ataaactact
    33301 ttcagaacct ataaatgtat ctcttacaat ggcaaatgat agtttattaa aaaatttttt
    33361 agatggtgag aaagaacatt taaatgatga agaatttatt tataaattac aagattatct
    33421 gaatgtatat agaaataaat acttatatga ttctgttttt ttagtatcaa ctaaaactaa
    33481 taattattat cattttgatg gacttaatag aaatcttagt gtcaataatt cagagaatca
    33541 atggtattat actttcttaa ataaagagga tgaatactca ttaaatgttg ataatgatga
    33601 agcaagtgac aatagtatta cagtatttgt aaattgtaag ataaaagatg ataatggagc
    33661 aactatggga attataggtg ttgggttaaa ggttaattca ttacaaatgt tgcttaaagg
    33721 atatgatgac aaatttgatg ttgtcactca cttaattgat gataaagggt ttgtacaatt
    33781 agcagtagat aaaactggtc atgagcatat aaattttttt gaaaattcca gtagtgactt
    33841 gtctaattca aaaaaattaa tattaaacaa tgaaaaggaa caaaaaagtt tttggtattc
    33901 atctgaaaaa tcaaaacgtt atattgtatg ccagtacata cctagtttaa aatggtatct
    33961 tgttttagaa aatgatttta ctttaatgag taaacagctt tatatgcaat ttttaaaaga
    34021 cattggagtt atagttttaa ttataatatt tgtacttttt actattacac atgtgcttaa
    34081 aaaatacaaa aaacaaatag tgaagcttag tgtttcacag aaattagaat atcaaaagtt
    34141 gttaagccaa tctactgaag gactttatga aaatattttt gaaattgata ttaccaataa
    34201 tagagctggt tgtgaagatg agaatagata ttttcatgaa tttggattag ggcttaacac
    34261 tccatatgat gaagcactgc acacaatagc taaaaaccaa atcaaagaag aatatgcaca
    34321 aggttattta gatacattct tacctgaaaa tgtgattaaa tgttacaata gtggaattaa
    34381 taatatcagt tatgactttt taattaaaaa agatgaagaa agctatcatt ggattagaat
    34441 taatgcacga attttctttt ggacatcaga tgaatctgtt cgtatgatat cttatcgtaa
    34501 aaatatagat gaagaaaaaa atagagaatt actacttctc gaacgttcac aacgtgattc
    34561 tcttacaggg ctttacaata aagctacaac agaggaattt attcgttcat ttttaaaaaa
    34621 tgaaagtaat caagacttag aacacgtttt tctaatattc gatattgatg attttaaaaa
    34681 tgtaaatgat aaatatggtc atgtatttgg agactttgtt ataagtgaat ttgctttaga
    34741 attaaaatct caatttcgtg aggacgatat tgtaggacgt attggtggag atgagtttgt
    34801 agtattaata aaagacttta atagtaataa ctatgtactt atagataaat tagaacgttt
    34861 ttgctctaag attaatcaga aaaaatttgc tgagcaagca ggattttcta ttggatgtag
    34921 tattggtgta tcaatgtatc ctgaacatgg atatgtatac tctgaactat atgagaaagc
    34981 agaccaagca ctttactatg caaaaagcca tggaaaaaat tcttatcatg tattttcaga
    35041 ggattctact gatagtattt catttcatat agaccctaga gacataaaag tattattaga
    35101 aatggctact gatggtgttg tcaaatttgc ttgtatggaa aacttaaaac tactttattt
    35161 taaccaaaaa atgcttgaat ttactggata ttcagctcaa actgttactt ctacagattt
    35221 taatattttt tcgcctgtac tacaagatga cctacaaatg gtactcgata cattaaaaga
    35281 agcaatctct aaaagggaga cttttgaggt agtttttcgt ttttgtcata cagatggtca
    35341 tatttttcct gtaaggatgc aagggaagtt tgtaagtgaa ttatatcaaa atcgttatcc
    35401 tgttttttat gctatttata cagatatatc aaatatcaat actttattag aaaataaata
    35461 gtaaatgcta cagtaaaatc taaaaatagg atataataat attaatataa gaagattata
    35521 agtaaaacct gctgataaaa tagattattt taggcaggtt tttaaatttt ttatagtaaa
    35581 tcttattttt agtcaatagg gtttattttt taagaacttt attgattaaa aaatagctac
    35641 gcacacttgt gactttagtc atgagttagt agctaaatta gtcagcatat aggg
//
LOCUS       DAMKOJ010000042        32068 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000042 DAMKOJ010000000
VERSION     DAMKOJ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32068
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.044"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..427)
                     /locus_tag="PC592_002094"
     CDS             complement(<1..427)
                     /locus_tag="PC592_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDF4056067.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPVETNLLKSEVERLSE"
     gene            complement(499..1881)
                     /locus_tag="PC592_002095"
     CDS             complement(499..1881)
                     /locus_tag="PC592_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF4056068.1"
                     /translation="MITGYGLLVAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFRISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(2017..2922)
                     /gene="garR"
                     /locus_tag="PC592_002096"
     CDS             complement(2017..2922)
                     /gene="garR"
                     /locus_tag="PC592_002096"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDF4056069.1"
                     /translation="MEVYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDIDKSAVDEL
                     ISCGAKYASVLEMGRECDIVFTILPNGTIVQDVLFGADGLAKTLKEGSIVVDMSSVTP
                     TESVLCANKLKERGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SLLIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            3306..3977
                     /locus_tag="PC592_002097"
     CDS             3306..3977
                     /locus_tag="PC592_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4056070.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEIIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIIEIFQIRSAIEGFCTFLITSQYKEA
                     RAIETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYKTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            4079..4627
                     /locus_tag="PC592_002098"
     CDS             4079..4627
                     /locus_tag="PC592_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056071.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILKKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            4889..5197
                     /locus_tag="PC592_002099"
     CDS             4889..5197
                     /locus_tag="PC592_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056072.1"
                     /translation="MFNKVYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(5358..7148)
                     /locus_tag="PC592_002100"
     CDS             complement(5358..7148)
                     /locus_tag="PC592_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056073.1"
                     /translation="MKKSKSFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGIPGASVNFDYVTKILVILACIYVANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQNRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADTESE"
     gene            complement(7148..8875)
                     /locus_tag="PC592_002101"
     CDS             complement(7148..8875)
                     /locus_tag="PC592_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056074.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSVLLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKENENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(9120..9701)
                     /locus_tag="PC592_002102"
     CDS             complement(9120..9701)
                     /locus_tag="PC592_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDF4056075.1"
                     /translation="MLEVVNMRGVVNMRKVILYIATSLDGYIAEEDGSVSFLDEISSV
                     FKNEQEDDYNTFYDTIDTIIMGNSTYVQIANELSPNEWYYKGKECYVYSNIINEITEN
                     VKYTNLEPKKLIEQIGREKDKKDIWIVGGGDIVKLFMKDNLIDDYYIYILPIILGRGI
                     SLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            9999..11111
                     /locus_tag="PC592_002103"
     CDS             9999..11111
                     /locus_tag="PC592_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF4056076.1"
                     /translation="MKISEVSTPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKLECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     AEAVSKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIERVIEVDIRENSKQIIL"
     gene            11300..12508
                     /locus_tag="PC592_002104"
                     /pseudo
     CDS             11300..12508
                     /locus_tag="PC592_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12758..13591)
                     /locus_tag="PC592_002105"
     CDS             complement(12758..13591)
                     /locus_tag="PC592_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4056077.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENI
                     EDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGRKITWGIITIACLLIA
                     IIVFPKLPHQIPIQWNNGVANYVDKKFIYAYPAICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDIFVFIALLIIGVYKLFKKY
                     N"
     gene            complement(13918..14448)
                     /locus_tag="PC592_002106"
     CDS             complement(13918..14448)
                     /locus_tag="PC592_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF4056078.1"
                     /translation="MKSLILYSSLTGNTKKIACSIYEAIQGKKEIKNISELVDDSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASTKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKVKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EANVFAKNMMIKASTM"
     gene            complement(14530..15624)
                     /locus_tag="PC592_002107"
     CDS             complement(14530..15624)
                     /locus_tag="PC592_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HDF4056079.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFCDIAKS
                     GVALITLGDVSVRPSFHNMAMSLTDEDGVMKYKKIVDEIHNSGAKVSAQIFCSDYDVN
                     LIKDTMKMGITSHVEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLIGSFSSSIFNNRNDEYGGTCENRSRFASEIISSIRNEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLFSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPINNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMISMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTHSQFGCILD"
     gene            complement(15626..16072)
                     /locus_tag="PC592_002108"
     CDS             complement(15626..16072)
                     /locus_tag="PC592_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4056080.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNRIKKEFSDEEYKELVKKLHVVKDIKTAMEEE"
     gene            16378..17568
                     /locus_tag="PC592_002109"
     CDS             16378..17568
                     /locus_tag="PC592_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF4056081.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTKENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALENAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTNIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPSGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            17738..18700
                     /locus_tag="PC592_002110"
     CDS             17738..18700
                     /locus_tag="PC592_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF4056082.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALNLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILSKNKLNVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMIIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(18822..19484)
                     /gene="zmp1"
                     /locus_tag="PC592_002111"
     CDS             complement(18822..19484)
                     /gene="zmp1"
                     /locus_tag="PC592_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HDF4056083.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHAESTTIQQNKDILSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNVLNQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(19584..19669)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(19854..22757)
                     /locus_tag="PC592_002112"
     CDS             complement(19854..22757)
                     /locus_tag="PC592_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF4056084.1"
                     /translation="MRKGNKKALLISLIMILSMVMSTIYPTVSYALELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEEEKQTDNKKPEQMPEKEKPTDNKNPEQTPEKEKPTDN
                     KNPEQTPVGEKPIDSKNPEHTQEDKSTDNKKSEQSLEDEKTLDNKNPEKTPKEEKLLE
                     EENLLKVLEDELNEENEDYGFIVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSIT
                     FKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSIMQGKIGLEAYVKKVDED
                     TNAKIHIETTGKIENGSGDVDVEIKPGDKTEVPDAKGTLKKLVEGRKSTTVFMPVKNK
                     DINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNITQSKNSIS
                     VNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSVFDRGDNY
                     LLTKGHSGATNITQVGQVINYQISVNDDKSPISNVVITDNIPEGMRLTTSGEAGHDFR
                     VVEVPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFFI
                     AYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLSSSDNQ
                     IVKYKINMSTYGVYDAGQVNLLDEVNPALKISNIKYSDNLELKKEAGDGKNTIRLVNK
                     YEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNIAQINGSSPPGVETTKQGYAFEAKK
                     VDALDKNVLSGARFNLEDVSGNIVVKDLVSDEDGVIQSSVKKPGIYYLVEFRPPNGYE
                     KLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVPPNTDEPVVNPPVPPSTDKPKKPS
                     SPSDTDETVVINPPVPPSEDMTNPPIPEVVNPPIPPSEEVIETPVKQIVPIPEVVKPS
                     VSEEKNNKVKDDTLVNPPVPPKTGDNTTIIGEILLVLGAIVGLIVLKRNKNAN"
     regulatory      complement(22870..22955)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(23082..24260)
                     /locus_tag="PC592_002113"
     CDS             complement(23082..24260)
                     /locus_tag="PC592_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF4056085.1"
                     /translation="MFSKILVKTFIRDSENVQNRDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPVPIKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEDMVNSIIELLLSYKHIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPVCLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYDCVIVVDKDFI
                     "
     gene            complement(24951..27725)
                     /locus_tag="PC592_002114"
     CDS             complement(24951..27725)
                     /locus_tag="PC592_002114"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF4056086.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAQALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITSKIEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAITSEGELNLIGSSRSYMKEDNLVFSGFVGIIDPLREGVK
                     ESIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFAQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRMMKN
                     SRTMNCNSKN"
     gene            complement(27896..29152)
                     /locus_tag="PC592_002115"
     CDS             complement(27896..29152)
                     /locus_tag="PC592_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF4056087.1"
                     /translation="MLKTTKISDPELYKIVANELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSTVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECKPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIILCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLGT
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(29224..30726)
                     /locus_tag="PC592_002116"
     CDS             complement(29224..30726)
                     /locus_tag="PC592_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF4056088.1"
                     /translation="MRALNVIERAGNKLPDPVTIFLLLCIIVVILSAIISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDSSYQGNPAMNLYFAFVSAIILTFAGAF
                     VTEKFIAPRFSKYSDAVNDKDMEELSELENKGIKYALLSLLAIVVIIVALCIGENAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGRVSNKIKNDKELVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKVLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEVIILLLFMSIGIPLGPGGGISYVL"
     gene            complement(30825..32009)
                     /locus_tag="PC592_002117"
     CDS             complement(30825..32009)
                     /locus_tag="PC592_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4056089.1"
                     /translation="MHELISISEKYKEDILDFFTDIHMHPELSFKEFRTTKVIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPICEEVDIEYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEK
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYTIACKSVCDLYSEDAIVDPVPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCMYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KK"
BASE COUNT        10631 a         5326 c         3833 g        12278 t
ORIGIN      
        1 tctctgataa tctctctact tcgcttttta ataaattagt ttcaacagga taatgtcctc
       61 tcatagtaga atcactacga cttatgatta taaaatcctt attaactttc tttgatacat
      121 ccacaatatt ctttgaaatt tctttatgcg cttttgtagt ttgagcaaca gtaaatcccc
      181 ttgaattagt aagtataaaa aacatactat ttttctcatt aaaaccttgt tccatactat
      241 ccttatccca atcagtataa acagaaatat catgaactgt ttgtacacct gttgggtcat
      301 catctaatac aacaattttt ctatctaaat gcttaagctc atctgcaaga agtttattta
      361 atctgtcctc atctacttgt ttaaaagtat taagtatatc tatgctaatt ggttttactt
      421 ctctcattta aaacgcccct ttatgtaatt tgtatagtct aaatgtaatt ttatataata
      481 taaacaatag tttgttattt atagacctgg aagtggtata attccattta taacactaag
      541 caataaaacc attataaatg ctacaactcc agcaatggtt cctccaattg tccaagagtt
      601 taaagtatct ttaactgata atccactaaa tcttgaaagt acccagaatc cagaatcatt
      661 tggaagggag aaaccaactc ctccagcaca tatagcaagc cctactaaaa ctggtgacat
      721 tccagttgcc aaaattgtag gtcctaaaat tgatgatgtt gttactaagg ctacagtagc
      781 agaaccttga gaaattctaa gcaaggcact taataaaaat ccaagcacta caactgatat
      841 actaagacca gacatagtat caactaagaa gttacctata ccacttgcat ttataacact
      901 gccaaacgca ccacctgaac ctgttatcaa taatattagc cctgctgaat cagcagcttc
      961 aataactaca tctcccatag gtttatttat gtatttcttt aaaaatccta ttgccaccaa
     1021 tattccaaga agtattgcta tgtttttatc tcctataaat gcaagcactc cactcattgt
     1081 agaacctttt tctaagaaca tactaaatac atttgatata agtataagaa gtattgggaa
     1141 caataaagaa aacatagaaa ttctaaaacc tggtacttta gaagaatcat catcttcaat
     1201 ttttatgcta tcttttccct gttctaaatt tttttctcta tcattctcat caatagcata
     1261 agctggatat ttttcaaaac gttttccata aatccatcca cctataagag ctgctggaaa
     1321 agcaacaatt atagaataaa gtataaaact acctacattt gcatttacat ttgctgcaac
     1381 tgccaaaggt cctggtgtag gtattacaag tgcatgacct actatagtcc caactcctaa
     1441 tgcacataca aaaaccatta gagatttctt agttactctc gaaacatact taattatagg
     1501 catcattata acgaaagctg catccataaa aactggaatt gaaattaaaa aacctgctgt
     1561 agttactgct aaagcactgt ttttttctcc agtcttagct aacaacccct ttgcaataga
     1621 ttctgttgct cttgattctg aaagaatatt tccgaatatt attccaagtc caattacaat
     1681 acctatactc cctaatgtat ttccaaatcc agtcgatatt gtggttgaga tttcatttat
     1741 aggcattcta accataaagc ctgtaattat agatgttata agtaatgcca aaaatggatt
     1801 tactttaaat ttaataatag atacaagtaa aattcctata gatataacaa atgctaccaa
     1861 aagtccatat cctgtaatca taatctttac ccctttatca ttctacttta ttatttatca
     1921 atcttatttt tcttttaata tgataattta accttgctgt atttatataa tctaatccta
     1981 atagtatgta tttagttata ttgatatatt taagtattaa ttattgtgtt tttttatttc
     2041 aacacctgct aacttttcaa aatactgtgc tattccacta tggtcatctt ccaaatgtcc
     2101 atgtactttt aatgtctgca taatttctaa taattgactt gtcataggta gtggtacatc
     2161 taaattatgt gctgtttgca ttacattctt aatatccttc aaattaatag atatttttcc
     2221 acctggttta aaatcacgat tcataatcat tggtatcttt gcatccaata ttgtactacc
     2281 agctagcccc cctcttattg ccttatatac tttttctggg tctgcaccag cttttgccgc
     2341 aagtacaaat gcctcagaga ctgccgctat cgtcaaatta actattactt gatttgtaag
     2401 ttttgtaaca cttccactac cattatctcc aattaaaaga gatgaacttc ccattatatt
     2461 aaagaatggc tctactttct tataaatttc ttccttacca ccagccataa aagcaagcgt
     2521 accatcaatc gcttttggct cccctccact tactggtgaa tctataaatt ctaagcccct
     2581 ctcttttaat ttatttgcac acaatacgga ttctgtagga gtaactgaac tcatatcaac
     2641 tactatactt ccttctttta aagtttttgc caatccatct gctccaaata atacatcctg
     2701 cacaatagtt ccatttggaa ggattgtaaa tacaatatca cattctcgac ccatttctaa
     2761 aacacttgca tactttgctc cacatgatat aagttcatcc acagcagatt tatcaatgtc
     2821 atacaccaaa agattacatc catctttcaa taaatttttt gccattggct ttcccattat
     2881 tcctaatcca ataaatccta atttcatttt atagacctcc atatcttcac atttttgaaa
     2941 acgtttttta tgttttagag tatactacat accagtatac cggtcaatat aaaatataaa
     3001 agtatttatt ttaacaataa atagtaattt ttaaagttat ttattatttt tagttattct
     3061 atataagttt taatatacac tattttttaa atatcatata ctacttttac agttttgtat
     3121 ttgaactaat tttaattaat ctgactttag tgttaatcat atatcacact tcaacaattt
     3181 tttatatttt ttaatcttat atgcaattta aatttcaaaa gattgacctt atttttacta
     3241 tgttgtatgc ttaaaattat ataagttttt gtatttttat attgtttagg ggggtattat
     3301 taagtatggc tacatttaaa agattacaag aacaagcata tgactactta aaagaattga
     3361 tactatctgg agaaataata gaaaatgaaa tatattctga aacaaaactt gctagtgaaa
     3421 taggcatctc tagaacacct ataagggatg ctcttcaaag acttagtcaa gatggattta
     3481 tagatataat cccaagcaaa ggatttagaa tccatcaaat tacagcaaat gaaattatag
     3541 agatattcca aatacgctct gcaatagaag ggttttgcac ttttttaatt acaagtcaat
     3601 acaaagaagc tagggcaata gaaactataa gtaaattaaa acacctttta gataaacaaa
     3661 aagatatttt actgggtgat aaaaatttaa actcatttgc agaatacgat acattatttc
     3721 acacaactat agtttcatat gctcaaaata ctgaatttga caaaatgttt aacaattata
     3781 tgtacagaat aaaaaaatta gctctcgatt cattgtcaca tgagggaaga cttgaaacaa
     3841 cattaaaaga acacacagat atttttaata atattgcaaa tggatgtatt gaggatattt
     3901 acaaaactac tctaattcat atggaaactc ctaaatacat taatttagaa gatttctgta
     3961 acaataagtt attttagcat tttactttta tttactaaaa aaatatatat cttaaattaa
     4021 tttcctaatt tattaaaaat attctataat tatattgtaa ctaatactat tctaaggagt
     4081 gatttttttg aacgaagatg ttgtaactaa tgaaactatc gacaaagatt atgctattga
     4141 agaagttcgt atggcatgca agcattttgg tgacttatat ttttattttt ccaaagtgtt
     4201 atttgaagag tttggtgaag ataaaactag cgaaatatta aaaaaagttt tatttgaaag
     4261 gtctgaagaa agagctattg ctatgagaga aagagctcat gaaaatggag atgaattaat
     4321 tgcagacaat attattagca caactgatgt tccatttcta ggatgggttc ctgaatttga
     4381 agagttgcat tgcccttatg gagcttcctg gcttttaaga tttgaggaaa atccttggtt
     4441 taaaaagttt gcttctcttt attgtgatgt tacagatact actgtagctg aagtatttac
     4501 aggagatacc tcccataaaa taacaaaaaa cattttatgg ggagataaaa gttgtgaaag
     4561 aatatatttt catgatgaca aggtatctga aggtaaatat acttatggaa ataaaaactg
     4621 taaataaata atttaaattt tctatattca tatactatat tttgtacttt ttcatataaa
     4681 tattataact agtcttttat tttacttttg tttaacctaa agataattta cttttaatct
     4741 atatgaatta tcatataaat aatcagaaag ttatctttat aaattatagt tttagattta
     4801 taatttataa aatatttatg ttctttgtaa aattttttag aagcttctaa tgttatgcta
     4861 taaaactatc tcaagaaggg ctgattgaat gtttaataaa gtatatgaaa aaaaagaatt
     4921 tatagttttt caagtaaaaa aaggttatgt agtttataat actagaaaga gttttgaaga
     4981 aggtcataca catttaaagc attttgaagc agcaaagaca gctattgatt tagcaataaa
     5041 taaaaagatt cctagaagca aagatggata ttatctgact agtttaattc gtataagtga
     5101 tgatggttat tacattgata agttaagcga attgttatat gttagagaac aaaaaggtaa
     5161 aaaagaaaag tactgtaatt ctggttatca gatgtaacaa gactagttac gaattataag
     5221 taccaaccat aagtaccttt ggtcttaaaa tcaaagagta tcagtaaatc tataaaaaac
     5281 aacttactga tactcttttt aattatatga ttaatatttg aatttgatac aaaatttcat
     5341 acaaaagttt atgttatcta ttctgattct gtgtctgcaa attggctatt ataaagcttt
     5401 tcataaaatc cacctttttc catcaattca tcatgattgc cctgttctat aatgcttcca
     5461 ttattcataa ctaaaatcaa gtcagcatta cgaattgtag aaagtctatg tgctataaca
     5521 aaactagttc taccattcat aagatttctc attgcttttt gaagcataag ttccaaccta
     5581 gtatcaacag aactagtagc ttcatcaagt atcaatattg aagggtctga tataaaagct
     5641 ctagctatgg ttaaaagctg tttttctcct aaagatatat tagatgcttc ttcatttaaa
     5701 aacatattgt atccatctgg aagagtggtt ataaagtgat gaacatttgc tacttttgct
     5761 gcttgtataa tctcttcttt agtagctcca aatctaccgt attctatatt ttcaaaaatg
     5821 gttccattaa ataaccatgt atcttgaagt accataccaa acattgagcg taaatcttta
     5881 cgtttcatat ctcttatgtc tactccatca attttaatag cacctttctt tacatcataa
     5941 aacctcatca ataagtttat taatgttgtt ttacctgctc cagtaggtcc aacaatagct
     6001 accatctgac cactttttac ttctgcattt aaatcttcta ttaaagttga attttctcca
     6061 tatccaaaat taacatgctc aaatgtaaca tttcctttta cattttctat cttaactgga
     6121 ttttcaacat caggtatttc ctcttcttcg tctaaaattt caaatacacg ctctatagct
     6181 gcaaaagaag attgtattac tgtggataat tgagtcattt gtgaaagtgg ttgatttatc
     6241 tgccatatat aacgcacaaa tgcttgtaaa tttcctactg ttatccctcc acttactgca
     6301 tatatagaac ctacaactgc cactgctgca attccaaagt aagttactaa tgaaaccata
     6361 ggattcatca tacttgatat aaattgtgcc ttaaatccat tttcacaaag ttcttgattt
     6421 acctttttaa actcttttat agagtcttct tctttaccat atagttttat ttcattaaat
     6481 ccagtataca tttcttgtac ttttccattt aattttccaa gagcattttg ttgtaatgaa
     6541 aatctatttt gagatttttt tactacaaat ttagatacaa aataactaat tggaattata
     6601 aaaagagcta taagagccat atatatatta attgtaaaca tcattgaaag tgccaaaatt
     6661 atgactaaaa ttgaatttac aatttgcata aaactctgtt gcaaagcatt tgatattgta
     6721 tctacatcat ttgatatacg acttaataca tccccaaaac tattactatc aaaataacta
     6781 ataggcaacc ttcttatttt attttctact tcatttctta aatctctcat tgtgttttga
     6841 atagcattcg taagtagaaa acttgaagta tacgtaaaaa ttgcattggc aacatatata
     6901 catgctaaaa tcaccaatat ttttgttaca tagtcaaaat ttacggatgc tcctggtatt
     6961 ccttttgcta tactaattac atctttagtc aattgtgtta ttatcaatcc ctcagtttta
     7021 ggtgcaagtg cattcatagt agctgctgaa attatacata taatagctat aataaaggaa
     7081 aatttatatt tctttacaaa tggaagaagt ctaccaattg ttttcttaaa acttttagac
     7141 tttttcatta ttctaattcc tcctttttta actgagatgt tgcaatttca tagtatattt
     7201 cacagttttt taataattct ttatgagttc ccattccgac aacttgtcct tcattgagta
     7261 ctataatctt atcagcatca ataatagaac taattctctg agcgacaatc aatacaattg
     7321 catcttttgt ttccttcttc agtttagcac gaagtattgc atcagtttta aagtcaagtg
     7381 cagaaaaact atcatcaaaa atatatattt caggtcttct tataatagcc cttgcaatag
     7441 aaagtctttg tttttgacct cctgatacat ttgctccacc ttcactaatc aattcatcaa
     7501 actttctagg tttttttgat ataaactcat atgcttgtgc aacttttgcg gaatattcta
     7561 attctgactc tcctgcctta tgtttcccaa atctaatatt atttgctatg ctaccagtaa
     7621 aaagcagtga tttttgaggt atgaatccta tcttttttct taaagctttt aaatcatatt
     7681 ctcttatatc tactccattt atcttaatgc taccttctgt tacatcgtaa aatctaggta
     7741 tcaagttaat tagagtactt ttcccactac cagtacttcc tataaaagca actgtttcac
     7801 ctgtttttgc agtaaatgaa atatccttaa gtacagaagc ttctccatct ggataggtaa
     7861 aagttacatt atcaaattct atgataccct tattttcatt ctccttaatt ccattttcag
     7921 gattttttat taatggttct tcatttaaaa gttcttttat tctatttgca gatacctctg
     7981 ctcttggata cataataaat accattgaaa aaagcataat tgaaaacatg gcatggaaaa
     8041 gatattccaa aaatgcaacc aactgtccaa cttgaagttc tccaatgttt atcttctcac
     8101 ttgaaatcca aaatacagct aaaacagcta tgtttaatag taaaaagaat gctggttgag
     8161 taattgacat aagcttaaat aatttcttag aaacattagc ataatatgta tttgtttttt
     8221 caaatcgctc agtttcataa tcatcatttc caaatgctct aattactctt attccagtta
     8281 aattttctct cgatataagg tttaatttat ctagtccttt ttgttgcttt gaagatattg
     8341 cctgagatac ttttgctatt attgctactc caataattat aaaaggtact gatatagcca
     8401 atactataga aagttccaca cttgttctaa ttgtcattat tatacttatg atgaacataa
     8461 ctggagttaa taaggcagtc cttagtagta tattaacaaa ttgttgaatt tgaaatgcgt
     8521 catttgttgt tcttgtaatc attgaagaaa ttccaaattt attatattca gtatgtgaaa
     8581 attcttgtga tttctcaaat atatcatttc ttatatctct tgttacactt gttgatacct
     8641 tagcagaaca ataacccaac aatacactac ctacaacccc tataatagaa ataataacta
     8701 ttactatccc catttgtttt atgtaagcta tattctgatt tgcaatacca ttgtcaatta
     8761 ttttagctat tatggttgga atccccaatt cgactaatgc aaaactaaat atagccagta
     8821 tgtttaatac tattaataac ttataattct ttaaataact taaaattaat ttcatatttt
     8881 tctcctttct taatttttga gctagtgtaa tcatataata atactaaatt tataaatgct
     8941 taattttata aaaaaaggag aaaagagtta acgcactctc ttctccagca tattcttttt
     9001 aatacaccct ccgacaagtc gcttatatgt taacatattt gacaagtaat gtcaattcat
     9061 atagccaaaa gtcttttaaa tgcttcattt cataacattg taacaaattg gcatgtaatt
     9121 tatttttgtt ttttactgta ttccaatttt acaagttctc caatattact agctttctta
     9181 aaattcaagt tagtcttgtc tataccagac ttaaatagtg aaattcctct ccccaatatt
     9241 attggcaata tatatatata ataatcatca attaagttat ctttcataaa taattttact
     9301 atatcgcctc ccccaactat ccaaatatct tttttatctt tctctcttcc aatttgttca
     9361 attaattttt taggttctaa gttcgtatac tttacatttt cagttatctc attaattata
     9421 tttgagtata catagcactc cttcccctta tagtaccatt catttggact taattcattt
     9481 gcaatctgta catatgtaga atttcccata atgatagtat caattgtatc gtaaaaagta
     9541 ttataatcat cttcctgttc attcttaaag actgaagata tctcgtccaa aaaacttaca
     9601 ctgccatctt cttcagctat ataaccatct aaacttgtgg caatataaag tattactttt
     9661 cgcatgttta ctacccctcg catgtttact acctccaaca tttatagtgt aattattcta
     9721 tgcaaacatc acttttttac tcattcaatg ataccctatt aataaatcct caaactaatt
     9781 taaataaact ttgcataaaa ttaaaaatat gttatataaa taatttaaaa ctccaataat
     9841 ttattgaaaa ttctaattat tacaaataaa cattgctctc tgttcatgct agttttataa
     9901 tataattata agctattaat attataaagc cgatattact aatataataa ttataatact
     9961 tatagttaat ttacttttgt tgaaaggtgg taaataacat gaaaatttca gaagtttcta
    10021 ctccaaattt tttgctagat ttagaccagt tagaaaagaa tatagataaa attcaacaaa
    10081 tttgtacaaa taataataaa caactttggc ctatgcttaa aacacataaa agtacttaca
    10141 tagcgagact tcaaaaaaat gcaggtgcta gtggttttct agttggaaca cttgatgaag
    10201 gtgaagcttt gataaaagca ggttttgaag atattatgtt ggcttatcct tacatgggag
    10261 aggtaaatat aaatagaatt gttactatgg catcaaaaat aaatttaatt tgtgctacag
    10321 ataatataga atgtgctaag gcttatagtg aagctttttc taaatcaaaa ctagagtgta
    10381 aactacttat tattgtagat tgtggcttac accgttttgg ggttgaacca gaaaaagtgg
    10441 ttgaacttgc tactgaaatt tctaagctag aaaacatcaa gattgttggt ataagctcac
    10501 atccaggtca agtgtatggt tgtagctctc cagaaggtgt tccagatgtt tgtgtccaag
    10561 aagattcttc tatggagaaa gcatacaaag ctctaactga taatggattt aatatagaaa
    10621 ttgtcgcttc tggtagtact ccaacagttg aagctgaagc tgtttctaaa actataactg
    10681 ctgtaagacc tggaaactat gtatactatg atgctataca gataggttta ggttgtgcta
    10741 ctgaagatat gtgtgctctt actgttgtgt gcactgtaat ctcaaaaaat agcagtggat
    10801 actatttaat tgattgtgga agtaagtgcc ttggacttga taaaggtgca catggaaaca
    10861 gtagtattgt tggttatggt agggtatgtg gacatccaga acttactatt gattcacttt
    10921 cagaagaagt tggaaaaatt aaagtaaatg gtgaaactga tataaaaatt ggtgatagaa
    10981 taagaattat acctaatcat tcttgttcca ctgcaaactt gacgagtaat ttattaggtt
    11041 ttagaggaga tacaatagaa agagtcatag aagtagatat tcgtgaaaat tcaaagcaaa
    11101 tcatacttta aaaatacatt tattttggtt ttagcgaaag tatatttttc tcaaaattat
    11161 tgttaataac taatgtcaat gttgtataaa taaaaacata aattctagaa atataaattt
    11221 aaaagaagag gctatctcaa aatagagata agcctctctt tcattgttga aattatgaaa
    11281 atatacttta tttcatataa atggatttgt atgtagtggt atagttccat atagtgaact
    11341 tataataaat ataaaagaca taaaagtacc attaaacttt ttaaagcttg atgaaagaga
    11401 tttttataaa tacttattca aactattaaa tagtcaaaaa gatattgact ttacaaaatc
    11461 atttatggat tttttaaaag aagacaacaa ttattatgat atatattcat taatagattc
    11521 taataaatgt ccatatacaa tcaaagattt taacatccct caacctgtgt atgactttaa
    11581 aaaattaaat gataaattat tggaaataca tttagactta ttgcgagata ataagattaa
    11641 cctttctttt actagaaatt acatcattag ttgtgaactt aataagcttg gatatgattg
    11701 tatttacatg gttccatcta cagaatcaat cttgaataca tttaaatctc tggtgaatga
    11761 aataacatta caaaacttag acaaaaataa atccgcaact tgtatagtta cagtaaatag
    11821 ttcagagtac ataaatgaag atttgatatt taaaaatgat gagatacaaa accaaatata
    11881 taacactatc ttaaattctc tatcaagaca tggattttat ggagtccagg tcaaaaaaaa
    11941 tgatatgaag atagagatac atactactaa ggaaatgtta aacaatatga ccaataacta
    12001 tacagatttt tttatttcag aagatttaaa agaaattaaa tatagcttaa atataggttg
    12061 gggtattgga aatacaaata ttcatgcaga acaaaatgct agtcaagcta atggtaaatc
    12121 tgctgctcta aatggaaact gtacttttat agtaaatgat actaatgata caataggacc
    12181 tttgtattca aataaaaatt ctaatactat tgaagatagc tcaatagcca ataaagttgc
    12241 ttcttttata cctctatcta atacaaatgt gtctaaaatc atgtgtatga ttaatgatag
    12301 aaattcaaat aatgtgtcag cagaaatatt agcagactat atgaacataa ctcttagaag
    12361 tgctaataga atattgagta tcttatataa agcaggaatt gcaactattg taaatacaaa
    12421 actcgataat caaagaggaa gaccaaaaaa aatatataaa attgatttct tatcttttct
    12481 aaataagatg cagaaattaa attcttaata tttaaatttt taataaaagc aatgtatttt
    12541 ctctaatttt aaagaatcaa aatgtttaaa ttttattaga atatacaact ttttacttta
    12601 aaatacctaa atcttttatc agtgaaataa accataatat atcgtagctt attagaaaaa
    12661 taaaataatt tcatatacaa ataataaaat ggccactaca atccataatt tgcagtggct
    12721 actttttaca ctatcactta ttacttattt ttaaaagtta attatatttt ttaaataatt
    12781 tatacacgcc tattatcagt aaagcaataa atacaaatat atctataaaa ataattattg
    12841 taacatgtct ggcaatattg taaataaaaa gtatagagaa tatttctata gacaacgcta
    12901 caaaacacat aaaatttgtt aaataatctg caatagtatc actataaaaa gcatgtattt
    12961 gtaaccatct ccatataaat ggacgtaaaa ggattctgaa tacaacacaa atagcaggat
    13021 aggcataaat aaatttttta tccacataat tagctacacc attattccat tggataggaa
    13081 tttgatgtgg caactttgga aatactatta ttgcaatcaa caaacaagca atagtaataa
    13141 ttccccaggt aattttcctt ccccatatat ataagaaact tacagagtca agtttaaaaa
    13201 caggtttgtt tttattccag tattctggca actcagttat gtattgctct actttcaaat
    13261 tcaaataact tagctcatca gactctaaca ttttattaca catagttttt gcattttcta
    13321 aatctgatat tttagtttcg agaactttct cctgtttctc tacaacttca actaaagata
    13381 ctttctgtaa tataatatta cggatatcat caatagtaat tcctaatgta cgtaaatatg
    13441 caattttttt gatgtcctct atattttcat ctgaatattc tctatagcca ttacgctcat
    13501 tacgaagggg tttaattaaa ttttcgttct cataaaaacg aatattagag cgtgtcaatc
    13561 ctgttttttc ttcaacttct ttaattgtca ttttaaacac tacctctcta ttctattaat
    13621 ttatagctat aatatagtct taaatacttt cactctataa aattgtatgt ttattatgtc
    13681 ttaaaatcaa actaattacc ttttataaat tttcatacaa taatatctcc tttcaataat
    13741 atctcttttt ctatatttaa aactatctta ttttctataa aataatgtat aaacaaggtt
    13801 tacagtcaag tatttttatt atttttttaa tttcataaaa aaagcatagc aaatcatgtg
    13861 ctatactttt tattggatta ttgattctat atcctatata aactctttat ttaactgtta
    13921 catagtacta gctttaatca tcatattttt tgcaaataca ttagcttcat atatttcttg
    13981 ttcatctgga tgactttgag attcctcatg gttatttaat tgttggcgaa tatgttcgtt
    14041 atcaggagaa agttttaaca tttctttata ttttactttc aatccttctg ctatcttacc
    14101 ttgacatatg aatgaaccta atatttcatt atcttttgga ataattgatt ctatcttttc
    14161 tattatacta gctccataac ttccttttgt acttgctccc attgttccaa atagtgctat
    14221 ctttttattg tgaatatttt caagtacttg ttttgaattt ttatcacaaa ttcccttatc
    14281 tacccaatag cctaagaata ctatatcata attttcatag tcaatactat catcaactaa
    14341 ttcacttata tttttaattt cttttttccc ttgaattgcc tcatatatag aacaggcaat
    14401 ttttttagta tttccagtta aacttgaata taagattaaa cttttcatga tgtatcctcc
    14461 tatttatcta aataattatc taacttacaa gaaaaatatt aacagatttt ttatttctac
    14521 aaacacaatt taatctaaga tacatccaaa ttgagaatgt gtctgcaagg catctgcaca
    14581 ctttttatta caataacagc attttttaat ctcatctact cttccatctt ttactttctg
    14641 taaccaatta ctatctgcta gtaattgtct tgacatagaa atcatatcta ctctattatt
    14701 tgaaataata ctttctataa aatctgggct agacaatttt ccaaccccac atactggaag
    14761 atttgtgtgt ttctttactt catcagctaa atataaaaaa caaccttcat ctttaaagta
    14821 aggatggtta ttgattggta tagtatcttc caattttgaa tgatttgcaa gtgttacatg
    14881 aaaactgttt acacctaggg attcaaattt tttaacaaaa tactcaactt ccgaaaataa
    14941 aactcctgca ttcccataat gaggattttc ttgtcttatt gcaaatttat agtctattgg
    15001 aatatcctta acttcatttc ggatactact aattatttca cttgcaaatc tgcttctatt
    15061 ctcacatgtt ccaccatatt catcatttct attattaaat atacttgatg aaaaacttcc
    15121 tataagccta tctccatgaa tttgaatcat gtcaaatcct gctttttttg catttaatgc
    15181 tgttacttta aataaattta taatattttt aatttcttct ttgggcatat ttgttatgta
    15241 atcttttact ccatcattca ttattttttt tatctcaaca tgtgaagtaa ttcccatctt
    15301 catagtatct ttaattaaat taacatcata atctgaacaa aatatttgtg ctgatacctt
    15361 tgcaccagaa ttgtgtattt cgtctacgat ttttttgtat ttcataactc catcttcatc
    15421 tgtcaagctc atagccatat tatgaaagct aggtctaaca gatacatctc ctaaagtaat
    15481 taaagctact cctgacttag caatatcaca aaatttttta attttttctt ctaatttaag
    15541 tcccatgctt gtaggtgcaa atgatactct attttttaat tccaaatttc caattttaat
    15601 tggctttaac aaattacaat acatcctatt cttcctccat agctgttttt atatccttta
    15661 ccacatgtaa tttcttcact aattctttat attcttcatc tgagaactct ttttttatcc
    15721 ggttatccca ttttgaaaat atatttttta tatctcctaa tacttcctct cccttatctg
    15781 ttactctcaa ctgaaaagct ctgctatcat tagggttttg gattttttct atgtatccat
    15841 cttgttctaa tctagatata gttcttgttg tatgagcctt atcaacttca aattctgtag
    15901 aaacatcatt caaagaacaa tttctatttt tattaatata gattaaataa aaatatagac
    15961 cattagtaag tttatatggt tttaaacatt tttcacaata aagtttaaag tttttttgta
    16021 aattacaaat aatatatgac aaactttcat actgcaaatt tttaaaatcc atcttaaatt
    16081 tcccctctat aattataata tatttgacta tatcaactat attatattaa acaattaata
    16141 tagtcaagaa tattttatta tctaaatcta tattttatta attctttaca aaactattat
    16201 ataaaataat catgattaaa ttagaaattg gaatttttaa tatgtactat acataaatat
    16261 attttatata aaagtttata ttttcaaaca aataattttc cgaaaattgt ctaaattcag
    16321 taaaaatatg gtaatatata cataagcaat ataaatctat aaaaaggagt gttacatatg
    16381 atatctaata aaatgcaaac tttagttgca aatagttccg ttataagagc tatgtttgaa
    16441 gaaggaaaga aactttctga tatttatggt gaagaaaatg tttttgattt tagtatagga
    16501 aatccaagtg ttgaacctcc agagactatt aaagcagtta taaatgatat tttaaatgaa
    16561 gaatctccaa atttagttca tggatatatg aacaactcag gatatgagga tgtaagagat
    16621 gctattgctg aacatataaa taaaaaagat ggattaaatc ttacaaaaga aaatttaatt
    16681 atgacttgtg gtgctgctgg tggtctaaat attattttaa aaactctttt aaaccctggt
    16741 gatgaagtta ttgcttttgc accgtatttt ggtgagtata aaaattatac agaaaactat
    16801 gatggaaaat taatagaagt tcctacaaat atagagactt ttgaaccaga tttagatgct
    16861 ctagaaaatg ctattacacc aaaaacaaga gctttaataa taaacactcc aaataatcct
    16921 actggtgtca tatattctga agaattatta aaaaatcttg gagaattatt ggattcaaaa
    16981 caaaaagaat ttaatacaaa tatataccta atttctgacg agccatatag agaaataatt
    17041 tatgatggtg ccaaagttcc ttgcgtacta aaatactata gaaattcatt tataggatac
    17101 tcttatagta aatcattatc tctacctggt gaacgtatag gatatattgt tgctaatgga
    17161 caaatggatg attttgatga tgttatgtct tcattaaatg ttgcaaatag gatacttgga
    17221 tttgtaaatg ctccatctct tttccaaaga gttattgcaa gaagtttaga tgctgaagtt
    17281 gatgtaaata tttataaaaa gaattttgac cttctatata atagtttaat cgatatggga
    17341 tattcttgtg ttaaacctag tggtacattc tatttattcc caaaagctcc aattgaagat
    17401 gataaaaaat tctgcaatga tgcaaaacaa tttaatttat tattagtacc aggttcttct
    17461 tttggttgtc caggtcattt tagagtatca tattgtgtat cttatgacaa agttaaaagc
    17521 tctttaccag catttgaaaa attagccaaa ttatataatt taaaataatt aaatcaaagt
    17581 aattcaaata attaactacc ttagtataga atacttacat tctatattaa ggtagtttat
    17641 aattttatgt actatatttt atacatacca tattattcca atatacttga atattcttat
    17701 ctatagtact aatataaatt acaaggaggt gtttgacttg aaaaaaggtt atgtttatat
    17761 aatactgact accttatttt ttagttcaat ggaaattagt ctaaaaactg tcactaatga
    17821 ctttaatccc ttacaaataa ctttatcaag attttttgtt ggcggtttag tcttactacc
    17881 ttttgctgta aaaagattaa gagctcttaa tctttctatt acaaaatcag acttaaaata
    17941 ctttgcattt ttaggtttta tgtgtgtagt agtaagtatg tcattgtatc aactggctgt
    18001 tctaaacaca aaggcatctg tagttgctgt tttgttcagt tgtaatccgg tctttgtaat
    18061 gcttttagct tacttaattt tgaaggaaaa aatatatagg cacaatgtaa tttcacttat
    18121 attagaagtt cttggaatta tagttataat aaatccattg catacaaaac taactcttag
    18181 tggaatattc ttaacattat cttctgctat tattttttca atgtatactg tatttggtaa
    18241 aagaaaaacc ttaaaatttg gtggaatagt tgtaacttgc tttagcttta tatttggtag
    18301 tttggaaatg ctgatattgg ttttactcac taaaattaat tttatcgcag atatattaag
    18361 taaaaataaa cttaatgtat ttgcaaatat acctattttt agtggatata ccttacacaa
    18421 tatgccaatt atgatttatg tattcgtatt tgttacaggt gttggttatg cactttactt
    18481 tatggcaatg gaagctacat ctactagtct tacatcttta gtcttcttct ttaaaccagt
    18541 aatatctcca atactagcat tattaatact taaagaaatt atccctataa acatgattat
    18601 aggaatttta ttgatagtaa ttggttcaat aatttctatt atacctacga taattactca
    18661 aatgcataat aaacatgttg aagccttgta taaggagtag taattgatac tctatcagtt
    18721 tatacataag acaaaattta ttagttttaa acgcaatata aaagagatgc tattacaata
    18781 gcatctctta atttatattt attttaaatt tattaaatta tctatttagc taggttttgt
    18841 aaaaaactat aagtttgtgg acaagctgat tttaacttac tatttgtatc ttgatttaga
    18901 tagtaatacg caaatgcttc tgcaaaaaat tcttctggat atacacctaa gtagtttaca
    18961 ttccctaaag aacgtccttc tttagcaaat atttgtttaa attgtgctga tttagatata
    19021 tcatttaata ctatatggtc tattgcatgt gctgtttcat gtaattctaa gtttattgca
    19081 tcatgacctt tacctttgtt actaaatcct attctaagag ctactgtgct tccacctaaa
    19141 cccggaacat catcccaagt ttttccagtt ccttcccatc ccttaggaac tacacctttt
    19201 aaataagcat attctttttc atctgttagc tttccactta ataattttat ttttaagtta
    19261 ttttgattta atacatttaa atactttcca tctatattag ctagtctatt taccatagca
    19321 ttagcttcat ttttatcgta atttccagtt ggaaaaacta ctatctgact aagtatatct
    19381 ttattttgtt gtatagtagt actctctgca tgtgcactta ctggaactga acttattaag
    19441 aatattgata ttatagctat taataatttt ttacttggtc tcatattatt ccctcctttg
    19501 agttaggccg ggagtaataa atttcaaaat aaaaaagata cccaagagta tctttgtata
    19561 tacaaaaaga aatttttact cttttcggca actggctggc atggtttact aaactttagc
    19621 ccctatagct ttgcgtgact aggtttccct agttttgcct catttaattt tatatctata
    19681 ttatagctta tatcttttta attgtctatg ctctttagaa tttttttcta aaaagttatt
    19741 atttttttac ataaatcttc aaaaaaaaat atcttctaac aatattttca ctattaaata
    19801 ttattttaga agatattttt taatattact tacatttttt ataatgttag ggtctaattt
    19861 gcatttttat ttctttttaa tacgataagt cctacaatag ctcctagaac taaaagtatt
    19921 tctccaataa ttgtagtatt atcccctgtc tttggtggta ctggtggatt taccaaagta
    19981 tcatctttaa ctttattatt tttttcttct gatactgatg gctttactac ttctggtatt
    20041 ggaacaatct gtttaacagg agtttctatc acctcttctg atggtggtat tggtggatta
    20101 actacctctg gtattggtgg atttgtcata tcttctgatg gtggtactgg tggatttata
    20161 actacagttt catctgtatc agatggactt gatggttttt ttggtttatc tgtgcttggt
    20221 ggcactggtg gatttaccac tggttcatct gtatttggcg gtactggtgg attttcttgt
    20281 cttatgtttt ctatatttcc aatatccact attctaccaa tatctttatt accaatttca
    20341 accttaattt tatccttcaa tttttcatat ccatttggag gcctaaattc caccaaataa
    20401 tatattcctg gtttttttac actagattga attacaccat cttcatcact aactaaatcc
    20461 ttaactacta tatttccaga aacatcttct aaattgaacc tagcacctga aagtacattt
    20521 ttatctaaag catccacttt tttagcttca aaagcataac cttgcttagt agtctctact
    20581 cctggagggc ttgaaccatt aatctgagct atattttgta tagtctcccc aacttttaca
    20641 tttgtgaagt ctgcatcaaa tgtaacccaa ctttgcacag gttcaccttc ttttatctgt
    20701 ttaaattcgt atttatttac taatcttatt gtattttttc catctccagc ttctttttta
    20761 agttcaaggt tatcagaata ttttatatta gatattttta gagctggatt tacttcatct
    20821 aaaagattta cttgccctgc atcataaacc ccataagttg acatattgat tttgtattta
    20881 acaatctgat tatcactact acttaaaacc tttttatcaa cttctttttt tgcgcttatt
    20941 aatccagaat ttttcttaaa gtttatctca tcatttttat caatttcact attatttgca
    21001 tcaagaacag ctctatttat atagctatct tcaatactaa ttacctttaa tgtataagct
    21061 ataaaaaact ttgattctac ttcttcttta ctaagattaa ttgtaaatcc agttataact
    21121 ttatcgactt gcccactttc atttcttttt tcttctactt tatatgaaat attgttggca
    21181 attttttctt tactccaagg agtccagcta ccattcattg gaacttctac aactctaaaa
    21241 tcatgtccag cttctcctga agtagtcaat ctcatacctt ctggtatatt atctgttata
    21301 acaacattac tgattggtga cttatcatca tttactgaaa tctgatagtt tattacttga
    21361 ccaacttgag taatatttgt tgcccctgaa tgtcctttag tgagaagata attatcccct
    21421 ctatcaaaca cacttacagt agcatcatct tcttgtatct tcttcccatc agattcaatc
    21481 ctagctacat tcttatattt attgccatgt tttgcatttt tgtcactgat tctagcctta
    21541 tatttaacag tatacgattt atctatattt ccaaaattaa ctgaaataga gtttttactc
    21601 tgtgtaatgt taaaatcact aacttctttt ccatcacttg ttactacact tacagagcca
    21661 tttatcagtg tcaatccttc aggaagctca tcatacaaaa taatatcttt taactcttcc
    21721 tgcttttcat ttacttgtat actgtaattt atatctttat ttttaactgg cataaataca
    21781 gtagttgatt ttcttccttc aacaagtttc ttaagtgttc ctttagcatc tggaacctcc
    21841 gttttgtctc caggttttat ttctacatct acatctccac ttccattttc tatttttcca
    21901 gtggtttcaa tatgtatttt tgcattagta tcttcatcaa cttttttaac atatgcttcc
    21961 aaacctattt tcccttgcat tatactttgg ccattaggta attctctaaa tgtaagtgta
    22021 tactctccat tactttctgt tttatcgaaa cattcacttg tataatctaa attaacttta
    22081 ttgaatacat ctggaacctt aaaagttatt gaatctcctg cttgtattcc ttttgaagtt
    22141 ggagtataag ttaaattaaa tgatattttt ttcattgatt ccgtttctat tgtattgtta
    22201 ttaattttta caataaatcc atagtcttca ttttcttcat taagttcatc ttctaaaact
    22261 ttcaataaat tttcttcttc taatagtttc tcttcctttg gagttttttc tggattttta
    22321 ttatctagtg ttttttcatc ttctaaagat tgttctgact ttttattatc tgttgactta
    22381 tcttcttgtg tatgctctgg atttttacta tctattggct tttctcctac tggagtttgc
    22441 tctggatttt tattatctgt tggtttctct ttctctggcg tctgttctgg atttttatta
    22501 tctgttggtt tctctttctc tggcatctgt tctggttttt tgttatcagt ttgcttttct
    22561 tcctctggag tttgttctgg ttttttattg tcgctttcct tttcttctcc agtggatgaa
    22621 ttagttgaac cactttgaat ctgactattc tctcctaatt ctaaagcata agatacagtt
    22681 ggatatattg tagacatcac catacttaaa atcataatta aactaattaa taatgccttt
    22741 ttatttcctt tcctcatata aatttctccc ctctaggtta tctatacttt ctaatcttcc
    22801 attaatatca tatataaatt aatttttact aaaaaattat acaaaaaaag ctatgaaaat
    22861 aaataaattt atattcatag ccggttgcac cactgactca gtatatccat aaggtgccca
    22921 ataatagaat atacttcaac atctctataa tatttcataa aaacaattaa aattgtttca
    22981 tttatattaa aaatacaatt atatacttct attatattat gcctttatac tattgtctat
    23041 cttttttaca ttttttacct tattatgaga ttaattaata attaaataaa atccttatct
    23101 acaacaatta cacaatcata ttcaggattt atctccttaa ctaattttgt tatatcttct
    23161 tttaagtcat cctccgacat gtttttggaa aattcggaag ggttaactac tatatcaaat
    23221 attaaattct tcttgctccc ctttccaact attctaaaat catgcataga ttttacaagg
    23281 ctatttttct taagtatttc ttcaagttct tttttggctg acataacttc tttatcttca
    23341 agacatactg ggtccatgtg aattactaga tatatatcta atttttcaga tatttctctc
    23401 tctgcagtat ctataatttc atgtatttcc attatatcta tgttggatgg aatttctgca
    23461 tgtatagatg caatacatct accgactccg tagttatgaa taattaaatc atgtgtacct
    23521 attatatgtt tataagataa caatagctct ataatagaat ttaccatatc ttcatctggt
    23581 gcttctccta gaagaggatt tatagtatct tttacaagag agaaaccagc ataaagtatc
    23641 actaatgata ctacaatacc aacatatcca tctataggaa aattagtaaa tctagctaca
    23701 ataaacgata taactacaca acttgaagta aatacatctc ctaaagcatc aagtgaaact
    23761 gcttttaatg ctgaagaatc aattttattt cccataaatt tattaaaacg gctcaaccag
    23821 attttaatca ttatagatgc aattaaaagt ataagtggta ttacttcaaa ttttatagga
    23881 actggattta ctatcctttc tatagatgac tttacaaatt gaagtccaac caacatcacc
    23941 ataaaagcta ctattaatgc tgataaatac tctattcttc catgaccaaa aggatgctct
    24001 ttatcagctg gcttacttgc taatttaaaa cctatcatag ttattgctga agatgccata
    24061 tcagaaagat tattaaatgc atcagccatt atagctatac tggatgtgag cattcctatg
    24121 aatactttta tcacaaataa aagtaaattg gataatatgc ctactacacc agccacataa
    24181 ccatatttat ttctaacatc tctattttga acgttttcgc tatctctaat aaatgttttg
    24241 actaggattt tggaaaacat gaaacttacc tccttgtcct ttattttatt aacaaatttt
    24301 agaatctata tctttattta tgataacata atttatatat aaaattctta aaaaattact
    24361 atacttcaat aaaatattat tatatatcaa tttaaataca aatcattata tttagcaaag
    24421 tttttatgcc ttaatatctg cttaatacat tctatgtcat tttttaaaaa gattatttat
    24481 tacgataata tcatttttcc caagtattcc ttagaatatg atttttttat tttgtctata
    24541 catattttaa aattatactg tatttatcta tattttataa ccttatgata cactataact
    24601 ataagatttt aaacggaaag gaatgaaata aatcatgttt tttatcagtg atatttacac
    24661 aaaatcaccc attaaatttg atacttcatt gcaaaaagag gtatataaaa tattacaaaa
    24721 gttaaatatt gacttttaac atattgacac agatgaagca attataatgg aagattgtgt
    24781 ttagattaat aaaaaattaa atatgaaaat taaaacaaaa caaatcattc atgatttctt
    24841 atcttttgca ggtcatacac catctataat tgaattgtaa tataaaatag cataaaaaaa
    24901 acacaaaccg caaagtcaca atatattggt actttgcggt ttcataagaa ttaattttta
    24961 ctattacagt tcatagttct actatttttc atcattctga gtattagctt tacaaattca
    25021 tttgacaata ggatagttga tgcaaatagt attattttta tccacatatc aaaatccaaa
    25081 gaaacagaat taaagaaact ctggaacact tgtgtaaata ttatttgaat tatccctgta
    25141 actactatta tttgcaatgc cagtttattt ttaaagaaat ttggtattgt actattcaaa
    25201 ccaaactctc tacaatttaa tgcattaaaa agggcactga atgcaaataa agaaaatata
    25261 acagtacctt gttcttctga tgtagctccc aatatattga aagctgattg agcaaataca
    25321 attgtaatta taagaatagc atttataata atatttacaa acatagacct agctattatt
    25381 ccagaatgtc tatttattgg ctttcttttc aatacataat ctctaacagg ttctaatcct
    25441 aatgctaagg ctggaggacc atccattatt atatttaccc ataataattg tattgtagta
    25501 aatggcatat ccttaccagt aagttgagat attatagcaa ttataaatgc tactatattt
    25561 acagtaagct gaaactgtat aaatctttga aagttctcat atatacctct tccccatttt
    25621 attccctcta ctatagtact aaaactatca tcagtcaata ttatatctgc tgcattttta
    25681 gatacttctg ttcctgaaat acccattgca attccaacat ctgcttgact aagagctggg
    25741 gcatcattta taccatcacc tgttacagct acaacttcgc cacttttttg aagtgctgaa
    25801 actattctca tttttgtatc tggtttactc cttgcaacaa tagatattcc tttgatttct
    25861 tctctcaatt ctttatctgt cagtacatct atataggttg cttcaactgc ctttttacca
    25921 tcatttaata atcctaattc atttccaata gctgttgctg tattgatatt atctcctgta
    25981 agcattttta catctactcc tgcattaaat gctttatcaa tggactcttt gacaccttct
    26041 cttaatgggt ctattattcc tacaaatcca ctaaaaacta aattatcttc cttcatgtaa
    26101 cttcttgagc ttcctattaa gttcaattca ccttctgaag ttattgcaac ttctgtttta
    26161 gaattactca tttttttata agcaaatcct aatgttctca tagatttaat ttgtaatttc
    26221 ttaatctcat ctaaaatact tttctctatt tttgaagtta ttggaacaat attttttcct
    26281 tgttgcacat aggaacattt ttttaataat acttctggtg ctccttttga aagcaatata
    26341 tctgaatcct cttgacgaat taatgttgac atcttctttt cttctgaact aaatggtatt
    26401 tgtgatatca aatacgtttg ttttctcatt tcattatagt tcttatcatt atgatataaa
    26461 agtaatgcac actctgttgc acttcctata tatttaaatg aattatcttc tttttctata
    26521 tctgcggttg aatttactat acagttttgt tcaaaatagc tgttactttg atactctcct
    26581 ccacttatat atttaccatc aacatatgct acctctacca tcattttgtt ttgtgttaaa
    26641 gtccctgttt tgtcagaaca tattacagaa acagaaccta tagtttcaca ggcttctttc
    26701 tttgttacta gtgcatttat ctttgccatc ttttgcattg ttatagctaa agtaatgttt
    26761 atcatagttg gcaaaccttc tggaacagtt gcaactatta aggcaataca aaccatatat
    26821 gcatttttag caggttctaa tgattgtaag aaagataata cactgcttgt atctaaaatt
    26881 aacatacctt ttctctgcat ctgtataatc ataaacatac acaataaagt agctattaca
    26941 cctgatattc ctgctatttt agctcccaat ttccctaatt taatctgaag tggagtttgc
    27001 tggtcttcat ttgataaatt ctgtgctatc ttacccatct ctgtcttatc tccagtatga
    27061 gtaacgacca ttatgcctct accatatgct acaagagtcc ccccaaatac catatttact
    27121 tgctttgcag gtattgcatc ctgttcgatt atttctgttt tagaataaac aacttccata
    27181 tctaatacag catcagcatt cttagctaca tcatcagatt ctcctgttaa catatcttct
    27241 ctaagtttca aatttataga ttgtataagt cttccatctg ctggtatcat atctccagtt
    27301 tctatatata caatatcacc tggtactaaa tcattttttg atattttaat tatcttccca
    27361 tttctaagta cttttacttc tatattttct gttaattttg acaaggcttg agctgctttt
    27421 ttagattttc cttcagttat tatacctata gaaattccaa taaaaatagc ccctaaaata
    27481 cctaatgcat catgtagttc tcctacaaaa gaacttatta ctgctgctcc tatgagaatt
    27541 aatatcatag gctctgtcaa actttctccc aactcgtccc aaaatgttct accttctttt
    27601 atagtaaatt catttaatcc atatctaagc ttcctttctt ctacctcatt atcatcaagt
    27661 ccaatttctg gatttgtttt taagtatttt aagacttctt tggtaggttt attataatac
    27721 ctcataactt tatccccctt gttaattatc tataaggaat tatatgctta tgatagcttg
    27781 tatattactt ttcaaaaaaa taaggtgttg attaatcaac accttatagt ggttatatat
    27841 tattaaattt tatgttatag gctttataaa ttgtgagtta tataaatcaa aatatttaat
    27901 cttcaaagta cccttctgga tataatggga acttagatat aagttcttgt gcttctgctt
    27961 tacattcatc taatacttcc ttattatcaa tattttctgc taccttattc attattcctg
    28021 ctatctgtat aacttctttt tctttaagac ctctttgaga tattgatgta agacctatac
    28081 gaacaccact agttacgaat ggtgattgtg ggtcatcagg tataacattt ttattaactg
    28141 ttattcctac atattcaaga gctttttcaa attgttttcc tgtaagattc ttgcttctta
    28201 agtcaaccat tactatatga ttatcagttc ctccacttac aatactaaaa ccatgtgaaa
    28261 tcagttcaga ggctagagtc tgagcattta ctacaacttg ttccattatc tttttaaatt
    28321 tatctgtacc taaatacaat agtgaaaagg cttttgctgc cactgtatta agatgtatag
    28381 aacctaatgt tcctggaaaa acacctttat caagtttctt tgcatgttct gctttacaaa
    28441 gtataatacc acttcttggt ccacagaaag tctttgttgt agatgaagaa acaaaatctg
    28501 cataaggtac agggctaggt attactttag ctgcgactaa tcctgcaaca tgtgccatat
    28561 ctaccataaa gtaagctcct acttcttttg caacctttga tattctttca taatctatta
    28621 atcttgggta tgaacttgcc cctgcaatta taagttttgg tttacattct tttgcctttg
    28681 cttcaagagc atcataatct atacgtccag tatttggatc caccccataa aattcatatt
    28741 tataaatatc atgtaaaaaa ttaactgtgc taccatgtgt taagtgtcca ccttggtcaa
    28801 gacgcatact taagacagtg tcatttggtt ttaatattga tgaatataca caatagttag
    28861 ctgtagagcc tgaatacggt tgtacgttta catgttctgc tccaaatact tcttttgcac
    28921 gttttattgc tagagtttca agtttatctg cttcttcaga acctgcttga aaacgagccc
    28981 ctggatagcc ttcttctgtt ttatttgtaa atacacatcc acttaattca agaacttctg
    29041 ttggtgctgt actttcagaa gctatcatct caatattatg ttcttgtcta accaattcgt
    29101 tagctacaat cttgtataac tctgggtctg aaatttttgt tgtttttaac ataataatcc
    29161 tcctcttaat taaagaatat attttattag attaatcttt attaataaat ttattataat
    29221 ggtctataaa acgtaagata ttcctccacc aggtcctaat ggtatgccaa tactcatgaa
    29281 tagtaacaat attattacct ctattaatgt aaatactact gagtatggaa tcatattcga
    29341 tatgacagtg cctataccta tatctttatc atatcttctg gcaaaagcta atataactgg
    29401 aaaatacgga aaaagtggac ttattggatt tgttgaagca tctccaatac gataagctat
    29461 ttgagttaat gctggattaa aatctagtag cataaacatt ggaacaaata taggtgctaa
    29521 aattgcccat ttcgcagaag cacttcctac aaataaattg ataaatccag ataacaatat
    29581 aaatcctatt atcaatccat aactaggtat ccccgactct gccaatactt ttgctcctgt
    29641 tattgataaa attgttccca agttactaag attaaataaa ttaataaatt gagatgctat
    29701 aaatgctaga actatatatc ctcccatatc actcatacta ctacccatca tagatactaa
    29761 ttctttatca ttttttatct tattacttac tcttccatat actaaccctg gagttaaaaa
    29821 tatgatagta attattggaa ctattccctt cattaaaggt gcattgcttg ataatataga
    29881 accagtttct gggtctttca taaatgcatt ttctcctata cataaggcaa ctattattac
    29941 cacaatagct aatagtgata atagagcgta ctttatacct ttattttcaa gctcacttaa
    30001 ttcctccata tccttatcat ttactgcatc actatatttt gaaaaacgag gagctataaa
    30061 tttttctgtt acaaatgctc ctgcaaaagt caaaattatt gctgatacaa aagcaaaata
    30121 aaggttcatt gctggatttc cttgataaga tgaatccatc atttgagctg caggtattgt
    30181 aaatccagct aataatacat ctgtagtact aagcataaca tttgctgcaa atcctcctgc
    30241 aacccctgca aaagctgcaa acatacctac aagaggatgt cttccaattc ctaaaaacac
    30301 aagtgctgca agtggtggta atattataaa tcctacatct gctgctgtat gtgataacat
    30361 acctgcaaat acaattgcta cagttacaag tttttgtgga actttactta tccctttttt
    30421 cattaacact tccataaatc cagatttctc agcaacacct gctccaagca ttgtaaccag
    30481 cactaatcct aatggagcaa atgattggaa gtttgtaact atactaccta agtatgattg
    30541 aatctgttct ttctctaata gatttactac ctttacaact tcttttgtag aaggatgtat
    30601 ctcttctact cctaaattag atataattgc tgacaatatt acaacaatta tgcatagtaa
    30661 taaaaatatg gttactgggt ctggaagttt atttcctgct ctctctataa catttagtgc
    30721 cctcattaat aatccactat ctttgttttt ttcctgtgaa ttaattttcc tcaaactaat
    30781 cccccctcat aaactttatc tccagaaatc ttctatctta aattttattt ttttaattta
    30841 tccatataat ttataacaga ctgacatagt acatttgtac ctaccaatat ggaattttta
    30901 tcagctttaa atttaggatt gtgccactga tacatacaat cttgctcttt gttgcctact
    30961 cctaaccagt aaaaaaatcc tggagctttt tccataaata tagaaaaatc ttctcctcct
    31021 gtagaaggta ctggatcaac tatagcatct tctgaataca aatcacacac agacttacag
    31081 gctattgtgt acatctcttt actatttata acggctggta aatcaaataa ataatctaac
    31141 tttgcagttg cttgatatcc acgagctatc tcacaaacta ttttttctaa attttcagat
    31201 attttctttc gtacttcatt actaaagctt ctacatgtac ctgtcatatc tactttttct
    31261 gaaattacat tatttgcagt tcctccattt atagtaccta ttgatataac agctgattct
    31321 aatggactta tgtttctact tactatggtt tgaatgccca ttataattgc acttgatgct
    31381 actatcgggt ctattgttct gtttggtata cctccatgac ctccaaatcc atttacttct
    31441 atcttaatag tatctactgc tgccattaac ccacctaact taacacctat ttttccacaa
    31501 ggtatatctg gatgattatg aagaccaaat atagcatcaa cttttggatt ttccattact
    31561 cctcgttcta ctaacatctt tgcaccttta ttgacttcct cggctggttg aaatataaat
    31621 tttacatttc catgaagact atccctaata tgagacaata catatgcaca tcctacaagg
    31681 caagatgtgt gtatatcatg tccacatgca tgcattatac catcatatct ggatttatac
    31741 tcaatatcaa cctcttcgca tattggcaat gcatcaatat ctcctcttag tgctactgtg
    31801 ggaccatcat acttcccttt taataaccca acaactccgg tttccattcc taagtctaat
    31861 atttctatgt ctaaacttac taataaatct tttatcactt ttgtagttct aaattcttta
    31921 aaacttaatt cggggtgcat gtgaatatct gtaaaaaaat ctaaaatatc ttctttatac
    31981 ttttctgaaa ttgaaataag ttcatgcata ctaacacctc tttaaaattt tattttttga
    32041 ttttttgata atttaactat aaattata
//
LOCUS       DAMKOJ010000043        31466 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000043 DAMKOJ010000000
VERSION     DAMKOJ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31466
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.045"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            23..1498
                     /locus_tag="PC592_002118"
                     /pseudo
     CDS             23..1498
                     /locus_tag="PC592_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            1723..2889
                     /locus_tag="PC592_002119"
     CDS             1723..2889
                     /locus_tag="PC592_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF4056090.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRIEQEIYGYTTRPDSYNESIVSWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKENDKIMIQEPVYSPFNSVVKNNSRELVISPLQKLEDGNYMMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPIAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEVSYNNGEPWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDKELESKLVQKGKVALNQGNSFGIGGSGYQRINLACPKGMLEEALRRIKNAIN"
     gene            2914..4356
                     /gene="nhaC"
                     /locus_tag="PC592_002120"
     CDS             2914..4356
                     /gene="nhaC"
                     /locus_tag="PC592_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF4056091.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICVVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLINKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLKFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDNEIEELEIFDTIQKRVD"
     gene            4359..4628
                     /locus_tag="PC592_002121"
     CDS             4359..4628
                     /locus_tag="PC592_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056092.1"
                     /translation="MRFEYYYLIQDITGILLAFIGFRMSIIGFRILSIKGISINTLLL
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMFLISIIINPRIKVSK"
     gene            complement(4707..6134)
                     /locus_tag="PC592_002122"
     CDS             complement(4707..6134)
                     /locus_tag="PC592_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HDF4056093.1"
                     /translation="MKLTKSIPSMLCLSIVLSLSPVSYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSGSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEELKDISE
                     IAIVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKNFIESKNISKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKKQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNTTAITQVGSGGNENAFKELKDLQVNS
                     NNKRVMYVTNTDKVNIRSDATIEASVIGALNNGDEVEVLEVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            6506..7375
                     /locus_tag="PC592_002123"
     CDS             6506..7375
                     /locus_tag="PC592_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4056094.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENTGEVKILSPAAAN
                     VLPPLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            complement(7487..8293)
                     /locus_tag="PC592_002124"
     CDS             complement(7487..8293)
                     /locus_tag="PC592_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HDF4056095.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATEYNLESLGGVKTLELIREHNKYIEKSMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFNRKGKIMGEYCKNHLWSLEAVYFKVGENVEVYEADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSNYNI"
     gene            complement(8307..9539)
                     /locus_tag="PC592_002125"
     CDS             complement(8307..9539)
                     /locus_tag="PC592_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF4056096.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYVLMKCFGIKDK"
     gene            complement(9997..11784)
                     /gene="aspS"
                     /locus_tag="PC592_002126"
     CDS             complement(9997..11784)
                     /gene="aspS"
                     /locus_tag="PC592_002126"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDF4056097.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKESFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEVIFKEVLDVELTLPL
                     PKMTYAEAMSRYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFSEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKASLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGADNIREVIAFPKNQNA
                     VCPMTNAPTLAENEQLEELSIKVDIKDNE"
     gene            complement(11858..13120)
                     /locus_tag="PC592_002127"
     CDS             complement(11858..13120)
                     /locus_tag="PC592_002127"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDF4056098.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            complement(13110..14666)
                     /locus_tag="PC592_002128"
     CDS             complement(13110..14666)
                     /locus_tag="PC592_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HDF4056099.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFNDFNANNNMESKNLIN
                     RLIYENGVLFSSTVYYENGNLKYESIQNIENMNLEFLDGFDGNKTIEEFLNSLDNESK
                     RNFKKLCKESIKKSMFVVLKQIFNSYVPWGILTGIRPVKIVHNLMDKNLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKIIRETNKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIREFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLDEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            complement(14757..15371)
                     /locus_tag="PC592_002129"
     CDS             complement(14757..15371)
                     /locus_tag="PC592_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4056100.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHIDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGNFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            complement(15386..15835)
                     /locus_tag="PC592_002130"
     CDS             complement(15386..15835)
                     /locus_tag="PC592_002130"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDF4056101.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAAKPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            complement(15860..18067)
                     /locus_tag="PC592_002131"
     CDS             complement(15860..18067)
                     /locus_tag="PC592_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDF4056102.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            complement(18141..18653)
                     /locus_tag="PC592_002132"
     CDS             complement(18141..18653)
                     /locus_tag="PC592_002132"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDF4056103.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKGVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            complement(18666..21116)
                     /gene="recJ"
                     /locus_tag="PC592_002133"
     CDS             complement(18666..21116)
                     /gene="recJ"
                     /locus_tag="PC592_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDF4056104.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKSAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYHVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQNEIPVAFAVINPKQEDCNYPFDSLCGCGVAFKIIQALTPKEEFKTSMYD
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILKEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLSIENGEATGSARS
                     IKGFNIFEALVKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NINVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     NIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRGTFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            complement(21129..22793)
                     /locus_tag="PC592_002134"
     CDS             complement(21129..22793)
                     /locus_tag="PC592_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDF4056105.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERIKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIEIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGILRTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKIYSEYNTKKILVMEKVNGTKLSDVEKIKRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLMEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNIEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            complement(23091..23588)
                     /locus_tag="PC592_002135"
     CDS             complement(23091..23588)
                     /locus_tag="PC592_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDF4056106.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKRYIDESYEWYLEAA
                     QNQKY"
     gene            complement(23617..24996)
                     /gene="scfB"
                     /locus_tag="PC592_002136"
     CDS             complement(23617..24996)
                     /gene="scfB"
                     /locus_tag="PC592_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HDF4056107.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVYYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSITPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            complement(25296..25442)
                     /locus_tag="PC592_002137"
     CDS             complement(25296..25442)
                     /locus_tag="PC592_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF4056108.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKKN"
     gene            complement(25472..26050)
                     /locus_tag="PC592_002138"
     CDS             complement(25472..26050)
                     /locus_tag="PC592_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF4056109.1"
                     /translation="MFKRYAEKMTSVLICNNVIDNNESKVYSYGFEILIAFVVNIATM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENLNI
                     DLFKNIIMIIASVSWVGICALCPIEHRSNPISDREKLVYKRIAIFISTVVLLITILSL
                     SLNIFVDYFTYSTFAMFWIFIMLVLGKLKAKI"
     gene            complement(26418..27848)
                     /locus_tag="PC592_002139"
     CDS             complement(26418..27848)
                     /locus_tag="PC592_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF4056110.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDSKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKALKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEEICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            28193..28858
                     /locus_tag="PC592_002140"
     CDS             28193..28858
                     /locus_tag="PC592_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056111.1"
                     /translation="MKGKIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKIDNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NGNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDNDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAV
                     NLN"
     gene            complement(29650..31362)
                     /gene="ptsP"
                     /locus_tag="PC592_002141"
     CDS             complement(29650..31362)
                     /gene="ptsP"
                     /locus_tag="PC592_002141"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDF4056112.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLEN
                     AVAVSKDELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTENVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDKETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEVQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLNMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADEVLNMGTAEEIKSYIEK
                     TFNI"
BASE COUNT        10270 a         5366 c         3507 g        12323 t
ORIGIN      
        1 actttagtca tgggaggttc agttgttgct atctataatt gatgatggaa ttatatgcac
       61 aaataatgat ggcataattc aattctataa ccatatggct agaaaaattt tatctataaa
      121 tgcaaatgaa atgattgact catttgttgg tgattgcata aaagacatta attttcaaaa
      181 catattgacc aataaaactc cattttttga gaaactgatt aaaataaatc atattgatat
      241 aaatttagag attaaacata tacaattaaa tgtatttgat ggatttatac tgaagatgac
      301 aaagttttct caattagaaa aaaagcaagc taaattaaga gcacagctag taaactctgg
      361 taatatcagt aaatatacat ttgatgacat attaggttct agcatacaaa ctattaatac
      421 aaaaaaaatt gctaacaaaa tggctcaatc aaattcatct atccttataa ttggtgaaag
      481 tggcactggt aaagaattat ttgctcaatc cattcatagt gcttctagga gaaaagatgg
      541 tccttttgta gcagtaaatt gtagtacttt tcaagaaaat cttctacaaa gtgaattatt
      601 tggctatgat gaaggggctt ttactggtgc taaaaaaggt ggaaaaattg gtttatttga
      661 attagccaac aatggaacta tatttttaga tgaaattgga gaaatggatt taaattctca
      721 atctaaatta cttagagtca tacaagaaaa acaagtacga cgtattggtt ctaataatgt
      781 cattgatatt gatgtaagaa taattgcagc tactaataga aatttaaaag aacttgtatc
      841 taaaaacatg tttagaagag atttatactt taggttgaat gttcttcccc ttaaaataca
      901 tccacttagg gaaagaccta ctgatatatt tgaaattttt ggttcattaa aatatgatat
      961 tccatgtaat tttagtctaa gtgaagaagt aaaagaaatc tttaaaatgt acaggtggga
     1021 aggaaatgta agagaattaa gaaacttagg agaatacttc tgttacttgg gaaaagatat
     1081 tataaaaata tgtgatttgc ctgagtatat attggatact atagattcaa attatagcag
     1141 aactgtttgt aataaagtaa ctgataatat aaaaaaatat aaattcaaca ttggtaaaga
     1201 caaaaatctt atgaaatacg actataattt taaaaggtca ctagatgaat acatatttat
     1261 actggataat ttaaaaaagg cttatgattt aaaagaaaga ataggcagaa aaagcttata
     1321 taaaatagca ttagaggaaa atagattttt gacggaacaa cagattagaa atatacttct
     1381 agaactacaa gaatttgggc ttgtaaacat acttgttggt cgtggtggtt caattataac
     1441 atcaaaagga gttgaatttc taaaaaatat aaacaggtct aataagttaa acagttaaac
     1501 ctattaaacc tatttaattg gattttcata tatttgaaaa tttattagaa ataacctttt
     1561 ccacaaagtt ttaaatataa ttaatattat tatcttatct atacgctgaa ataacttaat
     1621 attaaatatt aacttgtgaa taaatatttt ttattatcaa tcttggcacg ttgtttgctt
     1681 aatattatta acataaaatt aaaattactg gaggtattta caatgaatta taattttaat
     1741 gaaattgttg atagaagcaa taatttttca tctaaatggt cagagatgga aaaaaagtat
     1801 ggaactaatg atttacttcc tatgtgggta gctgacatgg attttaaagc tgcaccttgt
     1861 ataattgatt ccttaaaaaa tagaatagag caagaaattt atggttacac aacaagacca
     1921 gattcttaca atgaatctat agtgagttgg ttagatagaa gacataattg gaaaataaaa
     1981 agtgagtggt taatttatag tccaggtgtt ataccagcta taagtctttt aataaacgag
     2041 ctcacaaaag aaaatgataa aataatgata caagagccag tttacagtcc ttttaatagt
     2101 gttgtaaaaa ataatagtag agaactagtt ataagcccat tacaaaaact agaagatgga
     2161 aactatatga tggattatga agatatagaa aacaaaatta aagatgtaaa attattcata
     2221 ctttgtaatc ctcataatcc agttggtaga gtatggacaa aagatgaatt aaaaaaacta
     2281 ggagatattt gtcttaagca taatgtaaaa atcatatctg atgaaataca tagtgacatt
     2341 atattaaaaa aacataagca tattcctata gcatctattt ctaaagaatt tgaaaaaaat
     2401 acaattactt gtatggctcc aactaaaact tttaatatag ctggtcttca atcatcatat
     2461 gtaatactac ctgatgaaaa agactataaa ttgttagatg atgcctttac tagaattgat
     2521 ataaagagaa ataattgttt tagcttagtt gcaacagaag tttcatataa taatggtgaa
     2581 ccttggttag aatcattttt agaatattta gaatctaata tagattttgc tataaaatac
     2641 ataaatgaaa atatgccaaa acttaaagtt agaaaaccag aaggcactta tttattatgg
     2701 gtagacttta gcgcacttgg attaagtgat aaggaactag aaagtaaact tgtacagaaa
     2761 ggtaaagttg ctctaaatca aggaaatagc tttggcattg gaggcagtgg gtatcaaaga
     2821 ataaacctag cttgtccaaa gggcatgctt gaagaagctc ttagaagaat aaaaaatgca
     2881 attaactaaa aatatttaag gagaatttac actatgaaaa tgaatacaga aagaaaaata
     2941 ccttcattta gatattcctt gttagtaatg cttgcaataa tagctctaac atcagttggc
     3001 atagttgtat ttaatgcttc tataactaca atgtttttac tttcatggct tatagtagtt
     3061 cctgcagcta tgaagcttgg ttatactaat gatgaaatag aagcttttgg atttgaggtt
     3121 ggtaaagatg cctttcaatc aaacttaatt atactttctg ttggtgtact aatagcagct
     3181 tggatagctg ctggtacaat accaacagta gtatatagtg gactaacaat aataacccct
     3241 aaatattttc tgcttacaac actaatcgta tgttcactga cttctgttgc tactggtaca
     3301 tcttggggaa ctcttggaac ttctggtata gcaatgatga gtatcggtac tagtatgggt
     3361 attccccttg gtttaacagc tggtgcagtc atttctggtg ctttctttgg agataagatg
     3421 tcacctctat cagattctac aaacttagct gcggcagttt gtaagacaga tgtaattaca
     3481 catatgaaac atatgtttta taccacagga cctgcatatg taatatgtgt agttctgtat
     3541 acagtaattg gatttaagta ttcaaataat actatagact acgttcaaat aaatcaaatc
     3601 aaagatgtat taaattcaaa ctttcatatt ggtttagtag caatgattcc aataatattt
     3661 ttattattac ttttattgct acaaaagcca cctatcatat ctatactaag ttcagctatc
     3721 atgggactta ttatagcagt atttcaagaa ggagaaaaaa taggtgatgt tttaaattac
     3781 atgctatcag gatttactat agatactgga tttgtctatg ctgacaaact attaaatcgt
     3841 ggtggaataa tgagtatggc tgaaaccgtt ttactagtat ttgtagtctt tgttattgct
     3901 ggtattcttc aaaaaactgg attcttagaa gtactccttc aacctcttat aaataaaata
     3961 ggaaaatcaa gaactaaatt ggttggttct acttttatag taagctactt tgcaaatgca
     4021 tttagttcgt caatgatgtt tacttctgta tttgtaggaa ctctaatgtc tccaatatac
     4081 aaagaattta aattaaaacc acagaatcta tctagaatta tagaagatac agctacgctt
     4141 ggtggtccat taataccatg gaattcaaat gctgtattct gtgctcaaac tcttggtgta
     4201 agcccattaa aatttattcc atattgtttc ttaagttgga ttactcctat aatttcattt
     4261 atttatggtg taactggttt tactatgctt acatatacag ataatgaaat tgaagagtta
     4321 gaaatatttg acacaattca gaaaagagtt gattaaatat gagatttgaa tactattact
     4381 taattcagga cattacaggt atattattgg catttatagg atttagaatg tctattattg
     4441 gatttaggat actttctata aaaggaattt ctataaatac acttttactt gtaattaaat
     4501 actgcttatt tactatagca ggactgaatt tattaatatc taagtttgga attaggcact
     4561 ggatttggag tgtttgtatg tttctaatat ccataataat aaatcctaga attaaggtat
     4621 caaaatagaa ataattatta gactcaaaat tttacaaaaa agaaactgct ttacaaatta
     4681 aagcagtttt ttattgttac ttataattaa ataactggtg tatcagataa gtaatcatta
     4741 cttacataac catatccacc attatatttt atttttaccc atccagtagc aaacatttct
     4801 attgtttcca ctttgcttcc atatgaaaga tgccctattt tttcatcttc tgtacttggt
     4861 cctttcctaa catttagacc atctttttct tttacatact ttatttttat attttcatta
     4921 ctattatcgg gcttattatt tgtcaaataa gagccactaa catatccaat accttcattg
     4981 tattttattt ttacccatcc agtttttaac acttctaaaa cttctacttc atcaccatta
     5041 tttagagctc ctataacaga agcttctatt gtagcatcac ttcttatatt taccttatct
     5101 gtattagtta catacattac tctcttatta ttactattta cctgtaaatc ttttaattct
     5161 ttaaatgcat tttcatttcc accactacca acttgagtta tagcggtagt atttttattc
     5221 gaaaatacac tcttttgtgt tgcacttaat tgctctccta cgattagtac aggtgaattt
     5281 tcttttgatg ccagtactcc tactgctaaa gcatctataa gttgattttg ctttttcatt
     5341 ccatctttag ctacaaatac attatttaat ttgttagatg tataaaactt ttctattact
     5401 ttaccattag tttcatttct atctgctcca cctattcttt ctgaattagg taaactttgt
     5461 tttattttat ctgatacagc attagtagat cctattatgt atgatttact tatattctta
     5521 gattctataa aatttttaaa actagatata ccagatgcat cagacactgg aagtataacc
     5581 attccattag tagcagctac agaagctata ctaactgcgt ctgcaagacc tgtgtaccca
     5641 tttactatag ctatttctga tatatctttt aattcttcta tttttttagc tatacttaaa
     5701 gctgtttgat atctatcact accaccaact ctatcagtag ttaaattatt agattccaac
     5761 tgtttttgca catcatttga tacagaacca gatagtccaa ttatataaac ttttttaacc
     5821 cctaatcttt ttaattcttt ctcagtttgt gaatttagat tatttttttc tgtcaataat
     5881 ataggagcat tttttaattt agcaaacggt gttacagcca atgcatctac aatagattca
     5941 ctatttacaa ctacagcctc atttgcacta ctccatcctt ttttgcttac ttcaacagca
     6001 gtttgatatc tatcctgacc tactaaagta ttctcaactg ttgttctact tatttcattt
     6061 gcatatgata ctggtgataa gctcaaaact atagataagc acagcattga tggtattgat
     6121 ttagttaatt tcatcttgac tccccctaaa attatagtat ctaaatgttt cctatttaaa
     6181 atagtataac acaacaattt aagtaatatc attattataa aatattattt ttcttctcca
     6241 ataagctttt attcttacct gacattaata ctttactcat caaatgaatt ttttgtgtaa
     6301 ttaagctttg taataatgtt tccttagtta atcatattaa agctactttt ttaattagat
     6361 tatgtacaaa atataaatga taatttaaat aactttttaa tatattgtgg tttattatac
     6421 aaactttata ttataatgta taatgtggag ttgattataa aattgatata actaaagtca
     6481 tattaaaaga ggtgtatttt atactatgga tttattgcat cttaagtatt ttcaaactgt
     6541 tgctagaatg gagcacataa caaaagcatc acacaaatta aatatagcac aaccagcttt
     6601 aagcaaaact atctcttcct tagaaaagga acttggagtt cagttatttg atagaaaagg
     6661 aagatacatt gttttaaatg agtatggaag attgtttcta aaaagagtag atagcatttt
     6721 agatttggta gaaagttcaa aaaaggagtt acaagacact tctttagaaa atacaggaga
     6781 agtaaagata ttatctcctg cagcggctaa tgtgttacca cctcttttga gtaatttcag
     6841 aaaactatat cccaatatta cttttaatgt gtcacatact ttgccatcat cttataaaaa
     6901 aagtgatttt gatttgtaca tatcttcttc atttacaaag ctaaactcag aaaatagcat
     6961 aactttaaca tgcgaagaaa tactattagg agtttcaata aaccatcctt tgtcattaaa
     7021 ggatgaagta tatctaagtg aagtttcaga tgaaaacttt atagttataa cgaagggtga
     7081 gaattataga gaagtaattg atatcctatg cgaatcagct aattttaaac caaaaatagc
     7141 atttgaatct gattcgccat atacaattta tgctcttata aaatcacttc aaggagttgg
     7201 atttatatgt ggaaaatcat ggggattatc tcaagaccct gagattaagt tgttacatat
     7261 caaagatatt gaatttaaaa gatatttaaa tctttcatgg tttagtgaaa actatgaatc
     7321 taaagctgta ttgttattca aaaactttct tatcaactat tttaagaata tttaaatcga
     7381 agttgataat attaaagagg atatatcaaa gtataataaa tttaatctta atattgatac
     7441 atcctctctt tgtcatttta tattgaactt gtattataat atagaattat atgttatagt
     7501 tactttttct gtctttcaaa tatgggatat cttccctata cttttttatt tcatctaaat
     7561 caatctctga taatacatat ttttccctat acgtgtctaa ttgagttatt acagtacctc
     7621 taggattgca tattttactc tttccaaata gtattaaatt tgagtcatta cttactaaat
     7681 ttacccctac tgtatataca gtattctcta aagctctttg agatacattt aaatcccaca
     7741 tatcttcatc ttgtattctc catgcagatg gtataaatat tatttcagag ccttttaatg
     7801 tcaattctct ggatacttct ggaaaacctg catcataaca tatcattaca ccaaatctac
     7861 caaaatcagc ctcatatacc tctacatttt cccccacttt aaagtatact gcttctaatg
     7921 accatagatg atttttgcag tattctccca taatcttacc ttttctattg aatataactg
     7981 ctgaattata aacgtgtgta gacccttttt ctaaggttcc atatggagat atcagatata
     8041 cattatttct tttagcagct tctgacattg atttctctat gtacttatta tgttctctta
     8101 ttaattctaa tgttttaact ccacctaaag actctaaatt atattctgta gcaaatagtt
     8161 ctggtaaaca aattatatct gccccttgtt ttcctaagtc atctatcatc tctactgctt
     8221 tttctatatt ttttttaaca tctccaagta cactgtgttg ttgaattata cctattttca
     8281 ccttacgacc catgtaattg cctcctttat ttatctttga ttccaaaaca tttcattaat
     8341 acataataaa taaccatact cactacaatt ccatttattg gaggtattaa gaaatttatt
     8401 tttgaactat aatacgacgc tgcaaagcct atcaaccagc ttattactgc aatccaattt
     8461 attccttctc tatgcttata agttcttcct tgtataaaat aatactcaca ccacataatt
     8521 cctgctattg caggaactgc aattcccaag aaagataaaa atgactgaaa tttaaatatt
     8581 ataccagtag ctgctattat cgtacctatt agacctgcaa ctaaagtcaa aacatttctt
     8641 tttacatttg gaaaaatagt ttttagtgct aatccaccag aataagcatt tgatacgttt
     8701 gttgaccaag atgcaagtat taaaataaca aatgctaccc atccaaaacc taaattagcc
     8761 aatacttctg ttatatccca agtaggtgct cccatagaca ttacaccagc tgcaacttgt
     8821 tggaataagg aaataatccc taaacctaaa aaactaataa tccaaatatc ttttactctt
     8881 ctcgtatatc ttaactggtc aggtgatata attgcaccaa ctataacaag acctactaca
     8941 atattaagac cttcaaccat actcatagtt gtttgaggag tataattata aatagcttca
     9001 actccataag tagaaaaagc tttaaaaact ccccagacca ttaatatcat aagtggcggt
     9061 ataactaagt aattgaattt agccatagct ttaaagccat acagtgcaaa aacaaccata
     9121 aataatccaa gtataactgt aactaatgtt aggtttacac tcgggaatat cttttgtact
     9181 gataatcctg caacccctgc ttgtacacca aaccatccaa aactagttat accaagtaat
     9241 agagatataa gatactttcc tcctatctct ccaaatgccc ccttagctaa tacatacgta
     9301 tttagccctt ctttgtaacc tatatagcct tgtatcataa taattgcaac taatattaag
     9361 tttcctataa ttgatgtaat aatcatatta gaaagagtca ttcctaaaat taaagttccc
     9421 ccaaccatta gttcagatat agctatgtta gaaccaagca tattaaataa tggagctaac
     9481 catccaactc tttcctcttt tggaactgga tttaaaacta attcttctct ctcttgcaat
     9541 attatccctc cctttcttta taaaagaata atttctactt ttttctactt ttttttcact
     9601 ataaatagaa tttttcttta tataattgta attctattct acaaaaaagt ataatatcta
     9661 gtttgttatc aatttgatat aatttaagtt ataaatatgt aaatagtcta aatttattat
     9721 tttaatttaa tctattgagt catatattag atttatttca aatttgttat atattcttta
     9781 attaaaattg tgtactcatt acaaaagtag tttctaaaac aatcaagttt atgtaaaatt
     9841 tttaaacata gtgttttaat tacattggat gagaatacaa ggataattta tgaaaatata
     9901 tagagagaaa atataaaata gttctaataa aaaaaatctg aatataaata cactttatat
     9961 ccagactttt tacattttat tttctacaac tatatattat tcattatctt ttatatcaac
    10021 ttttatgctt aattcttcta attgctcatt ttctgccaat gtaggagcat ttgtcatagg
    10081 gcaaacggca ttttgatttt tagggaatgc aataacctct cttatattat cagctcctgc
    10141 aagtaacata acaagtctat caagaccaaa agctagacca gcatgaggag gagtaccata
    10201 cttaaatgct tctaataaat aaccaaattt ttcattagct ctttcctctg taaaaccaag
    10261 tgctttaaac attcttgatt gaacatcaga atttgatatt ctaacgcttc ctccacctat
    10321 ctcataacca ttcaagacaa tatcataagc tttcgctctt aaagatgctt tatcaccttc
    10381 ttctaactta tctaaatcct catccatagg tgatgtaaat ggatgatgca ttgctgagaa
    10441 tgtacctgtt tcttcatctt cttcaaaaac tgggaactca gttacccata gtaaattata
    10501 gacgttttta tccaatagat taagtctatt tgctacttca agtctaactt gtcctaaagc
    10561 atcaaatact attgagtttt tatcagctac aaataaaagt aaatctccta cttcagcatt
    10621 catccttgta agtatagcgt tcatttcttc ttcactaaag aattttgcta ttggagaagt
    10681 tactccttct tgtcctactt tcatccaagc aagacctttt gctctatatg tcttagcatg
    10741 ttcttctagt gatgatattt gttttctagt aaagtcatca gctttgcctt ttacgtttat
    10801 acctctaaca ctttttccgg gttgtgtagc atcagcaaac actttaaatc cacagttaca
    10861 aacaacatca gatatatctg ttaactcata tccaaatcta gtatctggtt tatctgaacc
    10921 atatctagac atagcttctg cataagtcat cttaggaagt ggaagtgtca attctacatc
    10981 taaaacttct ttaaatatta cttcaagcaa accttcaatc atactcataa catcttcttg
    11041 ctcaacaaaa gacatttcac agtctatttg cgtaaactct ggctgtctat ctgctcttaa
    11101 gtcttcatct ctaaagcatt taactatttg gaaatatcta tccataccac ttaccatcaa
    11161 taattgttta tataattgtg gtgattgtgg taatgcataa aattttcctg gattaactct
    11221 acttggtaca aggtaatctc ttgctccttc tggtgttgga gctattaaaa atggtgtttc
    11281 tatttcgcaa aatctattat ttgataagta atttcttgta atattcatta ctttatgtct
    11341 taattttaag tttctttgca tagatggttt tcttaagtcc aagtatctat attttaatct
    11401 tagtgcttca gaaacatcat catcatcttt tatataaata ggtggagttt ctgacttgtt
    11461 taaaagtcta agctcagttg caaatatttc tatatcacca gttggcatat tagggttttt
    11521 agattgtctt tcgcatactt ttccttttac agctattaca aattccgccc ctagtttttc
    11581 agctttttca aaagattctt tatctacatc tgtatcaaaa actatttgac ataatccact
    11641 tgtatctctt aaatcaacaa atacaagacc acctaaattt ctttttttct gtacccatcc
    11701 cataagtaca acttcttcat ttatgttttt ttctctcaac tctccacagt agtgagttct
    11761 ctttaaaccc tttaaagttt ccaagatact acctccattt tatttaattt taatgctata
    11821 tatttatcta atacacaaaa catcatactt tcttatttta cagcttttgc tttaattctt
    11881 caactaatgt acttaatttt acagtagttt gctctgatgt tttcatattt tttaatgtcg
    11941 cagtgtcatt tttaagctcg tcatctccaa ttactattgt aaattttgaa tttattttat
    12001 ctgaatattt aaattgcgct ttaacacttc tctctatatg gtctttatct gcacttatat
    12061 gattttgtct taagtctttt aataatttaa agcttcttgt atttgcttct tcacctatag
    12121 ttactataaa tatatctgta gattgagggt tttctatttc aattccatta ccttcaagtg
    12181 taagtaaaag tctttcaatt cctagtccaa atccaattcc acttatacct tttggtcctc
    12241 ctagttgttc aacaagacca tcatatcttc ctccaccaca tacagtactt tgagctccta
    12301 tatcattaga tataatttca aaagcagttt ttctatagta atctaaacct ctaactattg
    12361 ttttatcaat tacaaagttt atattcattt ccttcaagta ttcttgaagt ttatcaaagt
    12421 gagatttaca atcatcacac aaatggtctg caataaatgg tatatctttg atattttctt
    12481 tacatgtagg atttttacag tctataaccc tcattggatt tttttctctt ctctcattac
    12541 aagtatcaca caatatatca gcttttgaat caagatattc ttttaataaa gcattatact
    12601 cttttctgca aactggacaa ccaactgaat ttatactcac taccaaatca tttaatccaa
    12661 cttcattgaa aaattgaaca gctagtgcaa ttatttcagc atccattgaa ggagtatcgc
    12721 ttccaagtgc ttctattcca aattggtgaa attgtctttg tctaccagct tgtggtcttt
    12781 catatctaaa gcaaggtgta acataaaata attttgttgg ttgagtatct gcatataatt
    12841 tattttctat aaatgctctt actacaccag ctgtaccttc tggctttaga gtaatttctc
    12901 tatcaccttt atctttaaaa gaatacattt ctttttgaac tatatctgta gtgtctccaa
    12961 cacttctctt gaatagttct gtatgttcaa atataggtgt taccatttct tcatatccat
    13021 ataaagcaca tatttctcta aatttatttt ctacataacg ccatttataa gcctcttttg
    13081 gagttatgtc tttagttcct ctaggagctt tagtcaacat ttttatatac ctcttctttc
    13141 ttccttttta tcatttcatc tactctttca atgtattgtt caacattttt tacattttct
    13201 actctttcaa ttctatcttc atctacataa acaaatttcg atatagcacc tgcacctaat
    13261 gcatagttac tttgtttttc ttccataatt tgtatattgt aaatgcattc atatccttct
    13321 ttagcataac ctatattttc taaatttccc aacatatgtt tttgtctata catataatat
    13381 ggatttaaac ccatatcttt tgcatatttc attgataaat ctatcatttt taccatttct
    13441 tcatactgtg ttagatgttc tttatatcta tccatattta tatttaagtt ggatgccctc
    13501 tttatggcta atgtatgaac tgtaagactt tcaggagaaa gtttttttat ctcatccaat
    13561 gtgttcttta ccatatttaa atcttcatct ataagaccta aaattatatc catatttata
    13621 ttatcaaatc ccattctacg agccatatta aagcaatcta ctaaatcaga tactctatgt
    13681 tctcttccaa tctttactaa agtatcatca ttcatagttt gaggatttat actaattcta
    13741 ctaacattgt gtttttttaa cactcttagt ttttgttccg taatggtgtc aggtctaccc
    13801 gcttctacag taaattctct aattttactt aaatctaatt cattaaacaa tgaatttata
    13861 agcaaatcca attcttcctc atcaagtgta gttggagttc caccgccaat atatagagtt
    13921 tcaacttctt tattagtctc cctaataatc ttggcaaacc ccttaatttc ttcaatcaat
    13981 ttataaacat attctctttt taaatgtcca aattgcttta atgagtttga aggaaatgaa
    14041 caatatacac atctagttgg gcaaaatgga atacttacat aaagagaaat tttattttta
    14101 tctataggat acataaataa tcgctctctc ttagctattt caagagctaa atctattttc
    14161 tcatctatta taaaataatt atcttttaga atggttctta tgctattatc atctagattt
    14221 ttatccatta gattgtggac aattttgact ggtctaatac cagtcaaaat tccccatggt
    14281 acataagaat taaatatttg tttaagtact acaaacatgc tttttttgat actttcttta
    14341 cacagctttt taaagttcct cttactttca ttatctaagc tattgagaaa ttcttcaatc
    14401 gttttattcc catcaaatcc atctaaaaat tcaagattca tattttctat attctgtatt
    14461 gattcgtatt ttaagtttcc attttcatag tatacagtac ttgaaaataa tacaccattc
    14521 tcataaatca atctatttat taaattcttt gactccatat tattattggc attaaagtcg
    14581 ttaaacttaa attcactggt aaacaatttt ataagttctg ctacttcata cttataatca
    14641 tgtcctttta aaaaaacata caacatcaac ttaactcctt ctatttaaca gtagaagaac
    14701 cccatcacta atacagttat taaatatttt atactttttt aaatactaat ataaaattac
    14761 atgtaaggat ttgtcttctt ttcaacccct agagtactag ttggtccatg tccaggatat
    14821 actctaacag catcttcata tttacataat tttttaagtg atttttccat ttgattaaag
    14881 tttccactat acaaatcagt tctaccaata cttccagcaa acaaagtatc tcctgtgaac
    14941 atttcatctt caactcttat acacatacat ccttgagtat gtcctggagt atgcaagaaa
    15001 gtcattttta attcaccaag ttcaagcttg tctttatcat tcacatatat gtctgcatca
    15061 aattcttgtg ctccacatct cattgtataa cttagatttt tatttttgtc atttaataat
    15121 tctttttcat caatatgtgc aactacctta gcaccagttt tttctttaat atccttaaca
    15181 tatcctatat ggtctccatg cccatgagta aggattatat attcaatatt taattcattt
    15241 tcttttacaa aacttaatgt ctctactaaa cttccacctg ggtctataac tgcacatttt
    15301 ttagtctttt catcacctaa tacataagta tttactccaa agtaactatc tacaaatttt
    15361 tttataatca ttaaagtttt cccccttaaa aagatttact tgagtctaat agtattgtta
    15421 ctggaccatc gttagttaac tctaccatca tatgagctgc aaattgacct gtaccaactg
    15481 tcacaccttt atcttttgct ttttttacaa attcttcata aaggttattt gcaagttctg
    15541 gtttagctgc attactaaat ccaggtcttc ttccttttct gcaatctcca tataaagtaa
    15601 attgagatac tactaaaagc tctccaccta tatccattag agataaattc atcttgtcat
    15661 tttcatcttc aaaaattctc agattcaata ttttgtcaat catataatct acatcacttg
    15721 atttatcatc atgagtcact cctaataata ctagtaaccc cttatttatt tgacctatag
    15781 tgttttcatc tactgtaact ttagatgaag atactctttg tactactgct ctcatagctt
    15841 cctccctatt attttaactc taatttgtca ttctataaat actttctaca ccaggaattg
    15901 cttttaattt tttcattaga atttttaatt cctctgtgtc attaacttct acaagtaagt
    15961 ttatacttac aatactatcc ttaccttttc ttgcatttat tccatttaaa ctaagtttat
    16021 ccattgcaac aatatgagtt atctcattaa caattcctct tctgtcaata gcttttattt
    16081 gaatttctgc ttcaaactta ccctttcctg ctgaactcca tgaaacctcc accaatctat
    16141 tttggaagaa atcgccatta ttgtttgcat ttgggcaatc agctctgtgt atggccactc
    16201 ccctaccttt agtaatatat cctacaattt catctcctgg gagaggatta caacacttag
    16261 caaatcttac taagatattg tcaagccctt ttactataat tccttgtgat gcgtttttct
    16321 ttctcttttt actgtattct gtttcactta tattgtgttt atttaaatct tcttcttgta
    16381 tctgttgttc ttttttagct tttttaacct cttttaaata caggtctttt actttagata
    16441 caacttgtga tgacattata ccaccataac ctacagtggc aattaaatct tcaacacttg
    16501 gctgattgaa tttcttagca actaatgcca tatatttttc gacaagaggg tctttttgcg
    16561 gtatatcatg cttcttaaat tctctttcta atattgtatt cccacggtca acattttctt
    16621 ctcttctttc ctttttgaaa aattgtctaa ttctactctt tgcatttggc gtcttcacta
    16681 tattgagcca atctctactt ggtccattag aattagatga tgtaagcacc tcgacaatat
    16741 taccattttg aagcttataa tcaataggaa ctattcttcc atcaatttta gctcctacac
    16801 atttattacc tacatttgta tgaactctat aggcaaaatc tataggtgtt gattctgctg
    16861 gtaattcaat tacgtctcct tttggcgtaa atacataaac ttgactatta aatacatctt
    16921 ctttaagtgc atccataaat tcttgtgggt cttttaaatc tttttcccac tccatcatct
    16981 gtctcaacca ttggagtttt tcttcaactt ttgattcttt gctagagata ccttctttat
    17041 atttccaatg ggctgctata ccattttcag ctatattatg catctcatga gttcttattt
    17101 gtatctctaa aggttctcca tcaggaccta caacagtagt gtgtaatgat tgatacatat
    17161 ttggttttgg cattgctata taatctttaa atcttcctgg aataggtctc cataatgtat
    17221 gaactatacc aagtactgca taacaatcct ttacattatc aaccaatatc cttactgccg
    17281 ttaaatcaaa aatttcttca aaagtcttat gttttttttg catctttcta tatatactgt
    17341 aaaaatgctt tggtctacca tatacatcac atggtatgct taaatcttta aacttatctt
    17401 taagaagttc aacaattcct tgaatataat cttctctttg acttctcttc attgatactc
    17461 tactaactaa atcataatac ccttctgggt ccataaacct taatgctctg tcttctagtt
    17521 cccattttat cttggaaatc cctaatctat gagctatacc tccataaatt tcaagcgtct
    17581 cttttgcttt atattttgct ttttctggag gcatgtattt taatgttctc atgttgtgca
    17641 atctatcagc aagctttata agtataaccc ttatatcctt tgccattgcc aaaaacattt
    17701 ttcttaaatt ttcagattga gtttcttctt ttgaacgata ttttatttga ccaagtttcg
    17761 ttactccatc aactaaatcc gctacttctt tgccaaattc tttttttatg tcttcatagg
    17821 tatattctgt atcttctaca acatcatgaa gtaaacctgc tgttatagtt tcaatatcta
    17881 attccatctc tattaaaata tttgcaactg ctaatggatg aataaagtat ggttccccag
    17941 attttctata ttgtccttca tgcgcttttt ttgcaagatt ataggctttt tcaaccattt
    18001 caaaatttgc attaggtgca taaactttta ttttttcaat tatttcttgt aattctttat
    18061 catgcatata accacctatt ttgtataaaa ttttaatata tatgaaaata gttggtgtta
    18121 taccaactat tataaaagta ctagtatttt ataagagaat taacatcata gttagacaat
    18181 ttttctctcc cgtttaagaa ttttagctca atcaaaaact gcatagaaac tacttctcca
    18241 cctaattttt ctacaagctt agcagcagct tccatagttc caccagtagc caataaatcg
    18301 tctactattg ctactttttg acccttttta attgcatcct tatgtatctc taaagtatct
    18361 gtaccatact ctaatccata ctcataactc tcaacttcac ctggtaactt tccaggtttt
    18421 ctaattggaa caaatcctac tcctaaagca tatgctacag gtgtacccat caaaaatcct
    18481 cttgcttctg gtcctattac taaatctaca cctttatctt tcaattcttc aactatagaa
    18541 tctactgcat atttaaatgc atctccatct ttaaatagag ttgtcacatc tttaaaatct
    18601 atacctggct ttgggaaatc atcaatattc cttataaagt tttttaaatc catgggaaac
    18661 gcctcctaat aactgctatt gtattgtttt tctaaatttt ttagattatt gagtattaaa
    18721 ctctcattta agtctaattt tttctgtggt tttggcaata ttcttatgag tacagaattt
    18781 ttttcataat ttaaattaaa gtcaagtaaa tttaattctc taaacacatt taatatcgta
    18841 aaaaacttta atggaattac attaaaagtt ccccttatat ttaccatatc caaatcaatt
    18901 tcttttttta tgagtgcttg tttataaatt gttataaatt catctcttga tggaactata
    18961 ttactaacta cattctttaa atataatagg tctgttttat tataatattt tataatttca
    19021 ctttcttctc ttttattctc atatatatac gaatattcgc ctttattgta taaataatca
    19081 taaagaataa tattattata tctttttaag tctattttat caatattagg agaaaatata
    19141 agctctaatt tatcagtatt tttgctaaca tcttcaataa tattgtaatt tatgttaaaa
    19201 tccaaatcta taagtgatat atctgacatt gctctataaa atccatttat agaattagat
    19261 attattagtg tatctttttc aaaataatca aatatattta tatctgtatt tccatcaaat
    19321 aattcaaaat cagatacaga tatattatac aagctttgag tatcttttgg tattattttt
    19381 gacattaatt tcaatgaaag tttgtcatta cttgcacttt taggtcgagc caatcgaata
    19441 tctttaagta aaaattgtac tttcctattt cccatatagt tattttcatc taattgaaac
    19501 aatacatcca ctttgtctcc tactttatac attgatttta aatggctcat attaaatcct
    19561 atacattcat agcttttctc tttttctatg tttaatttca gatgttgttg attcttacct
    19621 ataactttca aatcttttaa aatgtaattt ctaactataa atctaggatt aggattattt
    19681 aatccaaaag gttctaactt atgtaattct tctacaagat ttaaatttat tacattttct
    19741 tgtaattcaa actcaacatt tatattctct atcatatcat cttcagttaa attataatct
    19801 gcaaatttat ttatttcatt tgctaaaatc tctacattat ctgaatccaa agataatcct
    19861 gctgcttgtt catgaccacc aaacttagtc atcaaatctt tgcactttac gagagcttca
    19921 aatatattaa atccttttat tgaccttgct gaaccagtag cttctccatt ttctatactt
    19981 agaagaattg ttggcttgta gtatttttca gttaactttg atgctacaat tcctattatt
    20041 ccatgttgcc aaccttcttt agctaaaacc aacactttgt catcattgta tctgctatta
    20101 gactttagca tttcttcagc ttcatgatac atcttagctt ctatcatctg tctttcatta
    20161 tttttttctt tcaatatact agctatttct actgcctctt cctgtgattg agtagtaaat
    20221 agctctactc ctaagtaaga ataccccaat cgacctgagg catttatcct aggacctatt
    20281 gcaaaaccta tatgagaaga acctatcttg tcactttcta cgccacagac ttttataagc
    20341 tcccttaatc caatattttt accttctttc attgatttta aaccattttt tacaattatt
    20401 ctattttcat ctataagtgg aacaatatca caaatagttg ctagtgttac tatttctaaa
    20461 taatcataca tactagtttt aaattcttct tttggagtca aggcttgaat tattttaaat
    20521 gctacaccac atccacatag tgaatcaaat ggataattgc aatcttcttg ttttggattt
    20581 attactgcaa aggctactgg aatttcattt tgacattcat gatggtctgt aattataaca
    20641 tctatgccca aatcatttgc tgtattgacc tcagacactg atgtaattcc acagtcaaca
    20701 cttataatca agtcacatcc cctagagctt ataagcttaa tagcatcttc atttatacca
    20761 tatccttctt ctaatctatt aggaatatag taatcaacat ggtaacctat actcttaaaa
    20821 tataagcaca agatagatgt agatgataca ccatcaacat cataatctcc ataaatccaa
    20881 attttttcgt tcttctcaac tgctgacttt attctatcaa cagctttttg catgtctttc
    20941 attaaaaaag ggtctcttaa ataatctaaa gatggattca taaatatttc tgaatctttt
    21001 tcagtacata tccctctatt ttttaaaatt tggcagattt ccggggaaat attaagtttt
    21061 ttgctaaatt cactttcctc tatcttacct ttatatttca atatccattt tttcaaattt
    21121 aattccccct aatctttttt gtattttgac ctaatacttc ttataactaa acaaagacct
    21181 attataaagg atataaagaa acctgctatc gcagtaaact ttatccatat attattttct
    21241 atatttggag atgcaattat aagagaagaa cctactataa tggatgccaa cactaaactc
    21301 aaagatattt gagatgttaa ctctattata caattttcta atcttgtcat tttaacatct
    21361 tcgatttgca tttttatgtt atttctttct atatttttta aaattgcttt taattgcttt
    21421 ggaatagttt ttatgtccag caatatttct tctatatttt gtcttgaact taaaacaaca
    21481 tttttagggt taaatttact cttataatga tgtttcataa actcttttcc catagagcca
    21541 aaagaaaaat ctgtatttaa agttctactt gttccttcta atgttatgac tgtcttggca
    21601 agagttacaa attgtgcagg catgactatt ttgtactgtc taaaaaatct aaatagttca
    21661 tttaatatat ctgttacatt tattttttct atagaaatat catagtaata atgtattaga
    21721 taaagtaaat cctgtctaag tcccttaata tcagcctctc catttaatgc atccatttcc
    21781 atcaatagat atattatctt atcaacattc ttttctacac ctgctaatgc aatttcattt
    21841 aattggttta aagttttatt atcaataatt ccaatcattc caaaatctat atatgctatc
    21901 ttgtttttag caactacgaa tatattacct ggatgtgggt ctgcatgaaa aaatccatga
    21961 gataatacct gtgtaaaaaa tgacctaact cctatttcaa caatagtttt tgtgttataa
    22021 cctagtctct ttattttttc tacatcactt aactttgtcc cattaacttt ctccattact
    22081 aaaattttct tagtattata ttctgagtat attttaggta tatatacttc atcgctattt
    22141 ttaaatatcc tagagaattt agttgcattt atagcttcaa atgtgtaatc aagttctctc
    22201 attaattgag tttgaaattc ttcaatcatt tgtactaaat ctaaattaaa atcttttttt
    22261 aaatccttta aagtatttgc aatagttcta agaatctcta aatcagattt tattattttt
    22321 tctatatttg gtctttgaat ttttacaatt acttcttctc ctgttctaag tataccttca
    22381 taaacttgac caatcgaagc agctgctatt ggttcttctt taaattctaa gaatatttct
    22441 tctatactta aacccacttc ttctttaaat atctcaatag ctatatttga gtcaaatttc
    22501 tctacatcat ctctgagttt tgatatttca tcaattatat cttggtctaa caagtctttt
    22561 cttgtactca atatctgtcc tatttttata tatgtaggtc ctagttcttc taaaactctt
    22621 ttaattctct caccagttgt catatttttt atttcttctg gtgggtcaaa tagtggtatt
    22681 ttataggcaa taccttctat atttagtctt tctacaataa aactaaaacc atactttatt
    22741 aaaacatatc cgatttctct atatcgcttt aaatttctat aacttattct caaatctttt
    22801 cactcctaag ataggtatac ccaaaaactt acaccttaat ttatcgtata tgacattatt
    22861 tcaccaattg atattctaat atcttatata ctctttaata tttaatttta tcacatatac
    22921 tagcaatttt attaaaatta tttaactcag ttgattttta tttttgacat tttatatctg
    22981 atttaaacaa atacttttta aaaactaaaa tatcaacaaa atctaataaa ataaattagt
    23041 ggttgcctca aaacagattt aaatatgttt tgaaacaacc actctttaaa ctaatatttt
    23101 tgattttgtg ctgcctctaa ataccactca taagattcat caatatatct tttatcttct
    23161 tctgtaagct ctctaacaac tttaccagga gagcccatta tcaaaacacc tggtggaaac
    23221 ttcttattag atgtaattag cgtacctgct cctatcagag tatattctcc tatttcagca
    23281 ttatccaata ttattgaacc cataccaatt aatacattat cactaatttt acaaccatga
    23341 actattgacc tatgcccaac tgttacattg ttaccaatta tagtttctgt atctccatgc
    23401 actatagaac agtcttgtat attagtattt tctccaatag ttattgggcc ttcatcacct
    23461 ctaactaccg cattgtacca tatacttgaa tctttgccta ttttaacatt tccaattaca
    23521 tctgctgatt ttgccacaaa tacactttca tcaattaaag gcttatcttc taaataatct
    23581 ctaatcatat ataaacaact cctttaaaat ataaatttag ttggttgctc cttctaacat
    23641 caacttagct tgtatcatta tagagcactc tgtacgcttt ctttgcattt cacatcccaa
    23701 ttcatatggc tttgatatat cattattaaa gtttatcgca tttgcatgac atccacctga
    23761 acagtaaaac ttattccaac attgcttaca ctcttcttta gtatatacat gcgcttctct
    23821 aaacatattt tttaaatttt ctggaagtac aatttcttca tcaaatatat ttgccatttt
    23881 aaattcttca tttccaacaa attgatgaca tggatagata tctccatttg gagttataga
    23941 aagatactca ttcccagccc cacatccagt tattctcttt attacacatg gaccttgatt
    24001 taaatctatc ataaaatgga aaaatttaaa tccatctcct tgtaattgtc tatctgcata
    24061 ctctacagca aatttttcgt attcttcaaa tatcttaggt aaatcttctt ctctaagtgc
    24121 atatggattg ctctcatctc caacgactgg ctctacagag gttaatttaa atcctaaatc
    24181 tgcaaaatgc ataacatctt ttgaaaaatc taaattatct cttgtaaaag tacctcttat
    24241 atagtaatac ttatcttttg ctcttttttc cacaagtttt ttaaatcgtg gtaatgtaat
    24301 atcataactt cctttatcat ttaaagttgg tctcatgtta tcattaactt cttttcttcc
    24361 atctaaactt aagactacat tgtgcatatt ttcatttata taatctataa tctcatcatt
    24421 taacaataca ccatttgtag ttattgtaaa tcttatattt ttattataat ctttttctac
    24481 acttcttcca taataaacca gttgttttac aacttcaaaa ttcattaaag gctctccacc
    24541 aaagaaatct atctctaagt tctttctact tcctgaatta gcaattaaat agtcaattgc
    24601 tgccttacca acttcaaaac tcataagctc tttttctcct ccaaaatcac cttgagctgc
    24661 aaaacagtat ttacatttta aattacaatc gtgagctaca tttaaacata aagcttttac
    24721 tacaggttct ctatgtacaa aacttggatg atattgatat gtatcttctg tatataaaag
    24781 accttctttt tccaaattta atatttcttc atacgcttca tttatttttt cttcttgata
    24841 ttttgatttt aatatttcta atatttcttc tttacttttt tctttataaa aatctaacaa
    24901 atcgtatgca acatcatcta acacatgaac agctccacca ttcacatcca aaacgatatt
    24961 atatccattc atagaaaatt tatgtatcat actcatacct tacctcctaa attactatct
    25021 atactaaagt tttttattat tttaattaaa ctttaccctt cattatatca taagtttacc
    25081 caaaatacat acaatacaaa aatgacttac tcaccgtaag tcatttcatt gaatacacta
    25141 tatcccccta aattggcgca ctaatatatt atcaaatagg tattaggctc ctataaaata
    25201 aataaaataa attttgtatc tgattttatc ttgttttaat cttatcaaaa tataataatt
    25261 ttttttaata attttgtata aataattgct tgtatttaat ttttcttctt taaattgctg
    25321 atttctttgg gtactttagg ttgatgaata atccaaggac aggtactatt agctgacaaa
    25381 atagcagtgc taagtgctaa tgagctagca aatttcataa atcttacaat aaactttttc
    25441 ataacttaat tctccctcat acatatttta cttatatttt agcttttaac ttacctaata
    25501 ctaacataat aaaaatccaa aacatggcaa atgtgctata tgtgaaataa tctacaaata
    25561 tattcagaga aagacttaaa attgttatca ataacactac tgtagatata aatatagcaa
    25621 ttctcttata aaccaacttt tctctatcac ttatagggtt gcttctatgt tctattgggc
    25681 atagggcaca aattccaacc caactaacac ttgcaataat cataataata tttttaaata
    25741 agtctatatt tagattttct ataattaaga ttgtagataa aattataaaa ataaaggtta
    25801 ataagcatct aaaataattg tctgcatgat aaccacctga aaattgcctt attggacaat
    25861 aacacattaa aaaaaacaat acatatgtaa atttaccaaa taaaaaacct ataaacagca
    25921 tggtggctat attaactacg aaagctatta atatttcaaa tccataagaa tagactttag
    25981 attcattatt atctatcaca ttattacaaa ttaaaacaga tgtcattttt tcagcatatc
    26041 ttttaaacat ttttacctcc aaaaaaattt tacatatata gagtacattc ttttttgaga
    26101 aaattcaata tactttacaa aactagttgt taaaaatgta aaactggtca aaaaaagacc
    26161 tatataattt tattattatt atttgtataa taaaacaatt ataataaaac aattttatta
    26221 agctttatat gcataaaaag aatatatcaa aatagagata accctctttt tcattgttaa
    26281 aagactaaaa atatatttta tttcatacaa aaagagtacc tcacaaacta aaaagcttat
    26341 tttgagatac ccactttatt tattacaaaa tattaatttt tatttgtttg catatatttt
    26401 atatatattt taacctttta actttgtttt tgttttacat actgtagtgc ctttctattc
    26461 tgttttactg cttcaaggca aactttttct gtttgattat caacaaattc taaagctcta
    26521 taattttgct ttactgcttc taaacatatt ttttcggttt gattatttac atatttcaac
    26581 attctataat cttgttttac tgcttttaga caaacttctt ctgtttgttc tttcacatat
    26641 ttaagcgctt cataactttg attaactgct tctaaacaaa tctcttctgt ttgttccttt
    26701 acataagcta aagcattata gttttctctt actgcctcta aacatattaa ttctgtctga
    26761 ttttctacat atttaagaat ttttccattt tgctttactg cttctacaaa tattctttct
    26821 gttggtatct ttacataact taatatttct tttatttcaa gttcttcaaa tgaacctctt
    26881 actgcttcta tacatatatt ttcagtctgt ttttttacat attgcagtac ttttccattt
    26941 tgtctaactg actccaagca aatttcttct gtttgctctt ttacgtactg taatgctctt
    27001 ccatcaattc ttactgcttc caaacaaatc tcttctgttt gcttatttac atactgtaga
    27061 gccatataac ttctttttac tgcttccata catatttttt ctgtctgttc atttacataa
    27121 tacaatgcaa agtcattctg ttttactgct tctatacata tttcttctgt ttgctctttt
    27181 acacaagaca gtgcactgta gttttctttt acagcttcta aacatatact attactttgt
    27241 tcctttacat aagctaaaga ttttccgtct ttttttacag cttctaaaca tatagctgga
    27301 gtttgctctt ttattccttt tagtatctct gcgacatcat ttttagatgc tctttctata
    27361 aatgctagac atacatcttc tgtctgctct tctacaaatt taaatacttc cataacatca
    27421 taagttgatg cattttttat agcttcaatt agtacatttt ctgtcttatt atttatgtag
    27481 tacaaagctc tgtagttctg ttttactgct tctatacaaa tatcctcatt ttgatttgtt
    27541 atatacttaa gagctttata tgtctgtttt actgcttcca tacatacttt ataagtcttg
    27601 tcctttacaa actcaattat agtaccatcc tgctttactg ctagcagaca catctcttct
    27661 gtttggtttt ctatgtcttt taactctcta taatcatatt ttactctgct taaatcattt
    27721 aaatgtactt tgttatcttc ctttgaatct tcctcattat tttctatatc atactcaaat
    27781 tcttcatcat ctaaatagtc atttttttct ggtaaaaata tagatttaat tttattcttt
    27841 atatccataa aattatcctc ctttaatatg attctatcat taaagtaaat cgtttttaag
    27901 cacttattta attaatttta tattaagttt ctttaaaagt ctattcattg ttgatagatt
    27961 atatttttat attaataatt ttatcttata tatgcggggt aataaagtta atagtggaca
    28021 ttttccatcc cattagtata cactatttat atttattact catttatagt gatttttttc
    28081 aaactttttc ttatttacta tatcatattt atccaattta tgatattatt taaatataat
    28141 ataagtttta taaagtatat taaatatatt ataagatgga ggtcgagtaa ttttgaaagg
    28201 aaagatagta caatataatt ttgcagatat agaggaagaa gtgtattcat tagattatgc
    28261 tatagcatgg aatacagacg aggaaaacgt aaacataata ccatttacaa ataaattctg
    28321 taaagaatct atagaatctt tttgcctagg taaaattgat aactttgttg aaatattgaa
    28381 tgaaggtttt gttgaaaatc atcattatgt acatttagat aaaatgatta gtgttcctaa
    28441 gaaaaaagtt aatttagtat atcaacaaga cacacatggt tatcttctaa gagatgataa
    28501 tggcaacctt attcctgcaa aaataacttc agagcaatct aaatctatat caagtaagat
    28561 ggagttattc tgtgctggtg aagaaaaatg tttaattaat atattactaa aggctgaccc
    28621 atcatatatt ttagatgtag atagtataaa agataaaaac attctaaatc taggttatga
    28681 gtctattgat agatataaag aatacaattt tgataatgat aagattttaa tattttttat
    28741 aaataaaaaa cgttattcag tgattatgaa aaaaacaaac aactctgata atgatttagt
    28801 ttccagaaac aatgctatta aagaattatt tactaataaa gcagtaaatc ttaactagta
    28861 ttataacttt aaattatatt actgattaaa ttaataatag tacacaaaga agctatctca
    28921 aaatagagat aagcttcttt tttatttttg aaacaacaaa atatatttaa tttcatgtaa
    28981 aagagagtgc cccataaact aaaaagttgc ttttgagaca ccctcttatt tataataaac
    29041 aaataaatcc ttaaacctat cgagtgatta taatttttag attgggttat cttttatttt
    29101 taaatttaag gtaactttct attctaaact ttaatctcta atcaatatca tcaactgtaa
    29161 caacttacaa ttaaatcttt aataatcaaa ctttagacta tctatattaa aactcaaatt
    29221 agatttagga tttatttgga tatcacattt attttattaa ctactaatca attattttta
    29281 cttataaact tattcttccc taattctatt attaaatact tttaattatt tttcaatacc
    29341 atattttttt aatttttatt atagtcataa gattattata ttactccatc ttaactgctt
    29401 ttaatggaat tttaagacga atcttacttt taatagtact tttatttctc ctaacatcca
    29461 tatctactgc aatcataata tatttttgtt tttttcacaa aacgactatt acacagatta
    29521 agtaattctt agtaattttt tataaaaaag agatgcttca aacttttatt ttgaaacatc
    29581 tcctttttaa tttgtaaaat ataattttgt tatttaaaaa aataaatttt agtaaatata
    29641 taacattaat tatatattaa aagtcttttc tatatagctt tttatttctt ctgcagtacc
    29701 catattaagt acctcatcag ctaatttttt catatctgac tctttaactg aagttattaa
    29761 ctttctagca ggaagtattg atattggaga catagagaac tcgtctaatc ccatacctaa
    29821 aagtattggt atcatttttt ggtctccagc agattctcca cacatacctg cccattttcc
    29881 ttctttatgt gcattgtcta taacagtctt tataagtctt aaaacagctg gattaaattg
    29941 attataaaga taacttatct tttgattcat tctatcaact gcacaagtat attgaatcaa
    30001 gtcattagtt cctatagaga agaaatctac atgtttagcc aatacatcag atattacagc
    30061 agcagatgga acttctatca tcataccaat ttctacatct ttagcataag ccacaccttc
    30121 agaatcaagt tctgctaaaa cttcttttac aacttcttta gcttgtaaca actcttctaa
    30181 agatgaaatc attgggaaca tgattcttaa tcttccatga acactagctc tatataaagc
    30241 tcttaattga gtcttaaata tatcttttct atctaggcaa agtcttattg ctctgtaacc
    30301 taagaatgga ttcatttcag gttccatatt taaataactt aattctttat ctccacctat
    30361 atccaatgtt cttataacta taggctttcc atccattcct tctaatacag ctttgtatgc
    30421 ttcatattgt acttcttctg ttgggaaaga atctctatcc atatataaaa attctgttct
    30481 ataaagacca acaccttcag catcattctt tattagacct tctatatcat taggtgttcc
    30541 tatgttacca gctaattcta catgtttacc atctaaagtt acagatggtt ttccctttaa
    30601 tagctgtaat gcttttctct catcttcata tttagctttt aattcagtat atttatttat
    30661 agtctcttta tcaggattca cgattacttc acctgtgtcc ccattgaaaa ctacaaagtc
    30721 tccatcctta acttttgaag ttatatcatt taatccaacg attgcagcta tttctaaagt
    30781 tctagacatg atagcagtat gagaagttct tccacctata tcagttaaaa atcctaaaac
    30841 cattttttta ttcatagttg ctgtgtctga tggagttaaa tcatgtgcta ttaatacaac
    30901 ttcttcgctt aaagcagaca aatcaacaac tttaattcct aatatatgtc taagtattct
    30961 atttgtaaca tcttttatat ctgccgctct ttctttcatg tattcattgt ccatagactc
    31021 gaacatgcta acaaacatct cttttatttc atttaaagca tactctgcat ttacattttc
    31081 agttttgatt ttatctattg cagaaccaat taattctggg tcttctaaaa ctaataaatg
    31141 tgcttcaaat atttctgctt cctctgctcc taattcttca gaagcctttt ccttaacttt
    31201 tactaattca tctttagaaa ctgcaactgc attttctaat ttagcaattt cagcttcaac
    31261 attatctata gatttttttt caattactaa ttcactatgt tcaactacta acgctttccc
    31321 taaagcaaca ccaggagaag caccgattcc tttgtaagcc ataaccctac ctcctaaaaa
    31381 atatcatcta gcacataaat gctataaatt tatataaata atttacattt ttatagtttt
    31441 acttacttat aattttttat aaaatt
//
LOCUS       DAMKOJ010000044        31207 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000044 DAMKOJ010000000
VERSION     DAMKOJ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.046"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            302..1846
                     /locus_tag="PC592_002142"
     CDS             302..1846
                     /locus_tag="PC592_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF4056113.1"
                     /translation="MRNFKKKLMFFLFICIILQITCTTSVYSLCKIYKNNSVNNFEFI
                     VSNNQLISKYALQMILIMATICIILIFYIIYDKLNFKIKLQKIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITNRLKIIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFEKNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTISVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVVEMAKELGMKVISEGVETEEQFELLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLIRG"
     gene            2022..2390
                     /locus_tag="PC592_002143"
     CDS             2022..2390
                     /locus_tag="PC592_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4056114.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEILKLITENLKGEL"
     gene            2392..3117
                     /locus_tag="PC592_002144"
     CDS             2392..3117
                     /locus_tag="PC592_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056115.1"
                     /translation="MDKNINNISQDGIVEFKGVNKSYGIKTVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIETKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEVIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            3111..3875
                     /locus_tag="PC592_002145"
     CDS             3111..3875
                     /locus_tag="PC592_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056116.1"
                     /translation="MLAKLLKYELKASGRVFIPLYIAILIVAVFNGIFMNTNILQIQG
                     IAILVLTSLFMALAVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVVSFIVAIFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILVLLLVMLTSYS
                     LFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPKENTNMIYH
                     FYQSSHVMFAILGDIVVIVALFFATKFILDKKLNLE"
     gene            4121..5371
                     /locus_tag="PC592_002146"
     CDS             4121..5371
                     /locus_tag="PC592_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4056117.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLENELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKVQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTELYEESEKVNIVDGIKSVIK
                     NKSTWYNSMIMLSFVGLTSAFISLWGVRYIMDVYCVSKSFSAFIVSFFTYGFIFGSLI
                     MDFVFAKIRSSKFNIIKYGAIIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNVVDGYKKSFVV
                     FIVLSIITIVSSHIGVKNDDFKAL"
     gene            5563..6447
                     /locus_tag="PC592_002147"
     CDS             5563..6447
                     /locus_tag="PC592_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF4056118.1"
                     /translation="MDTTKIDDISKLDLKNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYIEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFAARVWCNTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            6806..7423
                     /locus_tag="PC592_002148"
     CDS             6806..7423
                     /locus_tag="PC592_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF4056119.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTADSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQNFKVPYTDAINTFKDKYKDADVVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTENLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKIDSKKGTVLKVEKED"
     gene            7529..10060
                     /locus_tag="PC592_002149"
     CDS             7529..10060
                     /locus_tag="PC592_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF4056120.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSDYKVNLFDVIEHKQEDILAKISVSQGVLFGTPTILGDALKPIWDILVSL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMKAVKPFAVNFKPSNEEIDKLNSY
                     TGKFLDKLNATFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEIEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKAWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVI
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVIFKDGDSVDC
                     DMVVFSIGVRANTQMAHDTSVKIDRGIVVDKTLQTTVKDIYACGDVAQVENTSLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDDSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            10271..10891
                     /locus_tag="PC592_002150"
     CDS             10271..10891
                     /locus_tag="PC592_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF4056121.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFVGCLLSWIGSGLGTASLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDVKDFVPAMLAGKFVMFIVISYIASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHQSDKDDKMI"
     gene            complement(11058..11594)
                     /locus_tag="PC592_002151"
     CDS             complement(11058..11594)
                     /locus_tag="PC592_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF4056122.1"
                     /translation="MIKETHERGGYILALLILPFINNLYLVKYDIAYKIVLIIVYIYF
                     AYLGSLFPDIDMRGSYISKKFTLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKLISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11707..12381)
                     /locus_tag="PC592_002152"
     CDS             complement(11707..12381)
                     /locus_tag="PC592_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF4056123.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNVALEKYPELYNYSLCELLQNLDSLPKDIATAVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKAALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNAVNWNGALENYK
                     NLKSQD"
     gene            12584..14467
                     /gene="asnB"
                     /locus_tag="PC592_002153"
     CDS             12584..14467
                     /gene="asnB"
                     /locus_tag="PC592_002153"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF4056124.1"
                     /translation="MDGNISIYYKGDISKKENIKFKIKESLNNINNTRVSSRIEYKSE
                     AKIFDFERFNVIDVIYGNKPFEKYGKVIVFNGNIYNNHEIKEELIKRGHSFTTGDDIE
                     VLLASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKESAIIFSS
                     EYKFILEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKR
                     YNKLEFRSSTKFFYTKNHLGNRDVDKEEVRNIVVDSIRNHMEEHKEIGTFLSGGIDSS
                     IITTVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKALPN
                     VIYSLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVN
                     SPTYIKGILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEK
                     NIYEYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFL
                     YKDVFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSL
                     GGIVKETISNSNVDEFIDKKYVIKLLDMHLKGHRDNSRKIWTIFTFCLWHQLFIEHKN
                     VEY"
     gene            complement(14558..15994)
                     /locus_tag="PC592_002154"
     CDS             complement(14558..15994)
                     /locus_tag="PC592_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF4056125.1"
                     /translation="MICTIKPLKISIKKSNEPLIEFMSNTTYQNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPIIPYIRLSSLNINFDKEQTDKMLKIFNIYDSAK
                     FNSWDLYNINFPCKIENDTLNWTKKIAFKNTLDLFSMSMPNCTPSIIKNFAVKLLCWI
                     EYFLPKLFYNKVNTNISPKILYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSNIFELSRKTPNILEIPFERHIANINYNENTNKTSHPMNKPNSENTFNNTNLI
                     SKKIVQGEEVELSYEELAKLSASVVMIVVCNKENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSGYDLAVIKVDRKCKPIPVKIGKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            16323..16901
                     /locus_tag="PC592_002155"
     CDS             16323..16901
                     /locus_tag="PC592_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF4056126.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            16940..17518
                     /locus_tag="PC592_002156"
     CDS             16940..17518
                     /locus_tag="PC592_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF4056127.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLEAMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            17604..18233
                     /locus_tag="PC592_002157"
     CDS             17604..18233
                     /locus_tag="PC592_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF4056128.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGAGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            18223..20982
                     /locus_tag="PC592_002158"
     CDS             18223..20982
                     /locus_tag="PC592_002158"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF4056129.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMVSKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     LNSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQARKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKEE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            21069..22631
                     /locus_tag="PC592_002159"
     CDS             21069..22631
                     /locus_tag="PC592_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF4056130.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKNGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDKVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNVEFEEANIIEEKTSFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFNFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGVIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIIFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            22632..23768
                     /locus_tag="PC592_002160"
     CDS             22632..23768
                     /locus_tag="PC592_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF4056131.1"
                     /translation="MGININSFSKDKNSVDVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSSQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            23830..24906
                     /locus_tag="PC592_002161"
     CDS             23830..24906
                     /locus_tag="PC592_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF4056132.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETREFIYNEKKELSFINLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMKNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNEINPHFLWAK
                     KTLILSKIYGVLNEGVDYEELLKF"
     gene            24884..26122
                     /locus_tag="PC592_002162"
     CDS             24884..26122
                     /locus_tag="PC592_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF4056133.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDIGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLIATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYTITKLDTILSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITIDNKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQCDVYYHST
                     TRSPIINIDKHNYPIRSKFMLKSFYNMDIQNYIYNIDKQNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            26176..27264
                     /locus_tag="PC592_002163"
     CDS             26176..27264
                     /locus_tag="PC592_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF4056134.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYVKSKYNINLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNDKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFVL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDV"
     gene            27292..28083
                     /locus_tag="PC592_002164"
     CDS             27292..28083
                     /locus_tag="PC592_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF4056135.1"
                     /translation="MIVFSDLDRSIIYSNKFLSADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIYKFKDYLNVDGITNFKVAEDTFFYIVVDFSKFNLESIKEYTNV
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAIGDSIMDYGMLNISNK
                     AYLLKHGDINKNEIENSFLSSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(28198..28751)
                     /locus_tag="PC592_002165"
                     /pseudo
     CDS             complement(28198..28751)
                     /locus_tag="PC592_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            28945..30147
                     /locus_tag="PC592_002166"
     CDS             28945..30147
                     /locus_tag="PC592_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF4056136.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGVTEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            30204..31184
                     /locus_tag="PC592_002167"
     CDS             30204..31184
                     /locus_tag="PC592_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF4056137.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISEHKINILIGLE
                     GLSHIGSNIDSIDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVHKME
                     NLGMIVDVSHLNEKSFWDLMSIASKPVIASHSNAKSLCDVKRNLTDNQLKEIANTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NSSMPSVDGLESTHTAHNIVVELENRGYKKRDIDLISSGNFYRLFKYILK"
BASE COUNT        12191 a         3159 c         5386 g        10471 t
ORIGIN      
        1 tatttacctt aattttgtaa aattttctgt tactataatt atagaatgta gtatattcat
       61 tgtcttaact attgatttat atatttcata taggtataat agaaaataaa ttggattatt
      121 ttggcatata attgtttatt aaaatgtgct tatttttatt taaattgtct gaaaaatttt
      181 atttttatat tataatttta atattttctt ttcaaaacta tccattttac aagaaatgga
      241 aacttttgag atgtacttgt ttgccaataa aatagaggtg ttttaatagg aggaaatttt
      301 tatgaggaat tttaaaaaaa aattgatgtt ttttttattt atttgtataa ttttacaaat
      361 tacatgcaca acatcagtct attctttatg caaaatctat aaaaataact ccgtaaataa
      421 ctttgaattt attgtgtcta ataatcagct tattagcaaa tatgcattac aaatgatact
      481 tattatggct acaatatgta ttatacttat attctatata atatatgata aattaaattt
      541 taaaattaaa ttgcaaaaga tagcatatac agataatctt acaggagcaa atactataga
      601 taaatttgta attgatgcta acaaaatact atgtaaaaat actcaagtaa agtatgcttt
      661 attatatata gatattgata aatttaaata tataaatgac ctatttggat atgaagttgg
      721 gaatgaaatt ttgcgtaatt taacaaagat tattaagagt aatatatttg aagaggaaat
      781 gtttgcaaga atatctgcgg ataattttat tataattatg aaatatatag aagaagaaga
      841 tataacaaac aggttaaaaa ttatatttga agaactagac ttgtttaata ataatcagga
      901 agaaaagtat aagttagttt taagttgtgg aatctatttt atacttccag aagatagaga
      961 tatcaactca atcatagata gagctaatat acctcataaa atggcaaagg gaggacataa
     1021 aagttcatat gcattttatg ataataagat tcatgaccaa gagataaaag aaaaagagat
     1081 ggaaaataca atgttttcaa gtttagaaaa taaagaattt attatatact tacaacctaa
     1141 gatagagctt aatacaggag aaatacaagg ttcagaagca cttgttaggt ggaaacgccc
     1201 tgataaagga ttaatacctc caaatgaatt tataccattt tttgaaaaaa acggttttgt
     1261 tataaattta gatttatatg tgcttgaaga agtatgtata taccttagaa aatggattga
     1321 tgcaggaata aatccagtta ccatttcagt taatgtttca agaatacatt tatattgcaa
     1381 taattttata gaaacataca aaaatataat tgataaatat aacatacctg caaaatatat
     1441 agaacttgaa ttaacagaga gtatcatatt tgataatttt gatattttaa ttgacataat
     1501 gaataattta aaaaaaatag gatttttgat atctatggat gattttggtt caggatactc
     1561 atcattaaat atgttaaaag aaattcctat ggatatatta aaacttgacc aaaaatttat
     1621 tatggaaact tataatagta aaagaagcaa aataattgtt actaaggtag tagaaatggc
     1681 aaaagagtta ggtatgaaag tcatatcaga aggagttgag acagaagaac agtttgaact
     1741 tttaaaggaa gtaaaatgtg atatggcaca aggatattta tttggaaagc ctatgccaat
     1801 tgaagaattt gaacatttaa ttgtatctaa tttgataaga gggtaattaa tctgtattat
     1861 aaaaatttag taaattgtgt taaaaatgga ctctaatgta gtgttcattt ttttttgtaa
     1921 aattttttat gcttttatta aagagtcatt gacatatact ctgtattatt atattattgt
     1981 attaacgaac taatacaata gtgtaaaaag gaggtatgaa tatggaatgg gaacttgata
     2041 ataacaaacc tatatatata caattagtag aacatttaaa gttaaaaata atttcaggag
     2101 aaattaaaat aggatctaaa ttagaaaccg tgagagcact agcagaagat gctgaagtta
     2161 atccaaatac aatgcaaaag gctttaacag aacttgaaag acaaggttta gtttatagtc
     2221 agagaaccaa aggaagattt gtaacagatg ataaggaaaa aataaaagct atgaaagagg
     2281 aaatagctaa tgtggaaata aatacattaa aagtaacttt agaaaagctt ggatatgata
     2341 gagatgaaat actaaaactt attacagaaa atctgaaagg agaattataa aatggataaa
     2401 aatataaata atatttctca agatggaata gttgaattta aaggtgtaaa caagagctat
     2461 ggaattaaga ctgttttaaa gaatattgat ttaaatatac caaagggaaa aatagttggg
     2521 ctgttaggac ctaatggaag tggtaaaagt acaatgatta agttaatgaa tggattgtta
     2581 cagcctgata atggtgaaat tatgataaat ggaatgaaac catccataga gactaaaaaa
     2641 atagtttcat atttaccaga aagaacttat ttaaatgatt ggatgaaggt atctgatttg
     2701 cttaaatttt tctatgactt ttatagtgat tttgatgtta gaagagcaaa tgagatgatt
     2761 aaaagtttag atattgatgt aaatgaaaaa ctaaagacaa tgtctaaagg aactaaagaa
     2821 aaggttcaac ttatcttagt aatgtcaaga aatgcaagta tatatatatt ggatgaacct
     2881 ataggaggtg ttgacccagc tgcaaggtca tatatactta agactatatt aaaaaattat
     2941 tctgaagata gtactttgct gattgctacc cacttaataa gtgaaataga aaacatatgt
     3001 gatgaggtaa tattcatatc aaaaggagaa atagtgttac aaggagacgt tgaagcaata
     3061 agagaagaaa aaggaaaatc tatagatgca ttatttaggg aggaatttaa atgttagcta
     3121 aattattaaa atatgagtta aaagcaagtg gaagagtatt tataccgtta tatatagcca
     3181 tattgatagt agctgtattt aatggaatat ttatgaatac aaatatactt cagatacagg
     3241 gaatagcaat actagtatta acaagtcttt ttatggcatt agcagtttta actattgtag
     3301 ttacaattca aaggtttaga aaaaatcttt tgggagatga aggttattta atgtttactc
     3361 ttcctgttag cactagttca cttatattgt ctaaatgtat aacagcactc atatatgctg
     3421 tagttagttt tatagttgca atattcactt ttggagtact tatgcttttt ggtacttctg
     3481 gaattttatt acccgaaatt ttagatttat ttaacactag ttttaaatgg atttctgaaa
     3541 actttttaga tattttagta ttattattgg taatgcttac ttcatattca ttatttattt
     3601 tgttgttata tacatcaatt tcaatgggac aattacccaa atttaataaa catagaaata
     3661 tagtagcatt tgcttctttt atagctataa atatagtaat atcaattgtt ggagatgcag
     3721 ttggaagcat tttaccaaag gaaaatacaa atatgatata tcatttttat caaagttctc
     3781 atgttatgtt tgcaatactt ggtgatattg tagttatagt agcattattt ttcgctacaa
     3841 aatttatatt agataaaaaa ttaaatttag aataaatgtt tttatatgga gctatctttt
     3901 gagtaatgtt caaagatggc tcttattatt tatatattta attcatgcat ataatatgaa
     3961 taaggtttta tttctagtta aatatatcca tatgttgtat aatgatattg tgtgtaaaaa
     4021 tttgtaagaa taactataca cttgatataa gtaatatcaa aacaagtgtt ttgtaagtta
     4081 tattaaaaaa attaaaaata tatggattta aggagaaggt atgaaaagtt atacaaaggc
     4141 taagtggagt gtttggggta taattacatt ttcatttgtt ttagtattat ttttaagaat
     4201 gtcaactgct gttgtttcag acaatttaga aaatgagtta ggttttaatt ctatacaaat
     4261 ttcaaatata gcatccttct gtctatatgc atatgcattt atgcaaatac ctgcaggaat
     4321 tttgattgat aaatatggag caagaaaaat tagcagtctt ggaataataa tggcaagttt
     4381 aggttcaatt ttatttgggt tgattcaaag tatagaatta gcatatattt ctcgtgtaat
     4441 tgttggggca ggaacatcag taatattact ttgtatttta aaagttcaag gaagatggtt
     4501 taataaatca gaatttgcct ctgcaacagc caaattttca tttgtaggga atttaggagg
     4561 agttcttgct acttttccac ttgtgttcct gtctgaactt gttggttgga gaaactcatt
     4621 tttattaatt ggtataattg gtgttgtgat tggatgtttt atgtatatta ttgttagaga
     4681 tacaccaaaa gagtatggat tcaatgtaga tactgaacta tatgaagagt cagagaaggt
     4741 taatattgtt gatggtatta agtctgttat aaagaataaa tcaacatggt ataattcaat
     4801 gataatgtta tcttttgtgg gtcttacaag tgcatttata agcttgtggg gagtaagata
     4861 cataatggac gtttattgtg tgagtaagag cttttctgcg tttatagtat cattttttac
     4921 atatggattt atatttggtt cattaattat ggattttgta tttgctaaaa taaggtctag
     4981 taaatttaat ataataaaat atggagcaat aatagatttg ttcatatgga ttgtaattgt
     5041 agttgtatat caggtaaaac caccaattat agttttacca atatcattct ttattatggg
     5101 atgtatagtt atgtcacatc tacaggtttt taatgatgcc aagtataaaa ataaagaaat
     5161 ttattctgga ttggcaacta gtgttattaa tacttttgaa tttataggaa gtggaattat
     5221 taatttgatt atagctatct ctttacaagt aaattcatat aatgtagttg atggatataa
     5281 aaaaagcttt gtagtattta tagtactaag tattataact atagtatcat ctcatatagg
     5341 tgtgaaaaat gatgatttta aggcactata gtgttttact aatagtttaa tttaatgtta
     5401 tattttttta tatatataac aagtggttta tatttttcta atatgtataa ttggaatata
     5461 aatcttgttt actatgcaca aatggtattg tattatatta aatagaaaat aagaacttta
     5521 aactataata ttggttctaa aatataaggt aaggagtttt ttatggatac gacaaaaata
     5581 gatgatataa gcaagttaga tttaaagaat ctagatatta ataagatgga tatgggaggt
     5641 ataatggaaa gtctgttgga atgggctact acaagcggag taaaacttat aataggtata
     5701 cttatacttt ctattggatt taaaataata aaaaaatttg taaaccatgt tatgctatta
     5761 cttagtaaaa gagatattga tttaacttta agaaggtttt tgaagtctct tcttttgagt
     5821 gtacttaaag ttgctgttat aatcattgtt ctagaatatt ggggaatgag tttgtccagt
     5881 tttgctgctg tgatagcatc agccggggta gcaataggtt tggctttaca aggtagttta
     5941 tcaaattttg ctggaggatt tattatactt ttgattagac cttttaaagt aggagattac
     6001 atagaagcag cgggtcatgg aggaaccgtt gaacaaatag gactttttta tacacaattg
     6061 gttactccag ataataaaca gatacttata cctaatggtt ctgtatcaaa tgacagccta
     6121 ataaactatt cagcaaagaa tactagacga gttgacttga cttttagtgt aggatatgaa
     6181 gatgatatac tacatgttag aagagtactt aaagatattg ttaataacca taaattaata
     6241 ataaatgaac cagaaccatt tataggagta gtagaacatg gagataatgc cattaaattt
     6301 gcagctagag tttggtgcaa tacagaagat tattggacaa tttatcttga tttactagaa
     6361 gaggttaaag ttaggtttga cgaagaagga attacgattc catatcctaa aatggattta
     6421 acagtaaaag aattaaataa aatttaattc tttgatatag tgtttaaatt taagaatatc
     6481 atatagatat ttttataaga tttgtaaaaa aataataagt actgttattt tgtaagtaaa
     6541 aatataaaaa atatgagtgt ctcaaaatga actttttatt tcatgaggca ctctttttgt
     6601 gtaaaatcaa atacattttt attatttcaa caatgaaaaa gagacttgtt tatattttga
     6661 gacagtatct tttttgtgta gctttaatct tagtaagtat aaagttttaa aatcaataaa
     6721 atagtagaaa tttttaatat aaagggtaaa taaagggttt agagggcata atatagaata
     6781 aattaattat ttaaggagga tttttatgtg taaaaaaacg tatttattag tggtaagtat
     6841 acttatagca ggtttattaa ctgcatgtag tgggagtcca actgcagatt caggacaagc
     6901 acaagataat acaaaaaagg aagcaaatgc ttcaaataat gctttaaaag atgaaaaaaa
     6961 taatgaaaat ttaatggaac aaaattttaa agtgccatac acagatgcaa taaacacatt
     7021 taaagataaa tataaggatg ctgatgtagt agatttaagt cttgaaagag atttaaataa
     7081 atttgtttat actgtggaag gtgtagatga taataatgaa tataagatga aaattgatgc
     7141 taatacaaaa gatgtattgg aagataaaac agaaaatttg gattcagaag atttaaatgg
     7201 agttgcaaga aaagaaaaat tagatttaaa tgacataatt acacctcaac aagctatgga
     7261 aattgcatta aaagagcaaa atggaatggt taaagaatgg agtttagata aagatttaga
     7321 tgttactttt tataaaataa gaatagataa agataaaaat gaatatgaca taaaaataga
     7381 ttctaaaaag ggaactgtat taaaggtaga aaaagaagat tagaagattt aaattatctt
     7441 taaaataatt ttttttgaat aaattttgtt taaaatataa caagcagggt ataaagagac
     7501 taaataacta ttttaggagg agtacggtat gtcattaaaa tcactaaaaa taaaagaaaa
     7561 tttatattgg gtaggttcgc ttgaccctga tttaagagta tttgacataa ttatgtatac
     7621 accttatgga actacttaca attcatatgt attaaaagga acagaaaaaa cagttttatt
     7681 tgagacagtt aaagataagc attttgacaa ttatattgaa agattaaatg atttaaatat
     7741 agattttgaa aaaatagact atattgttgt aagtcatact gaaccagacc atgcaggaag
     7801 tgttgaaaag cttttggatt tagctaaaaa tgcaaaagta gtagcttcag aaacagcaat
     7861 taaatatctt aaggaaatcg taaacaaaga ttttgaatat gttgcagtta cagatggaga
     7921 tacattatca attggggata aaactttaga atttttctct gtacctatgc ttcattggcc
     7981 agatactata tacacatata taaaagagga caaaactctt gtaacatgtg attcatttgg
     8041 tagtcactat agtaatgata agatagtaaa tacacttgat gaaaatgaag aaaaggatta
     8101 cctggatgct ttgagatact attatgattg tataatgggg ccatttaaac catctatggt
     8161 aactgctata gaaaagataa aagatttaga tatagacact gtatgtccag gtcatggtcc
     8221 agtattaact gaaaatccta gaaaaattat agacctttat tacaattgga gtgtaaatga
     8281 acaaataaag ttagaaaaag aagttacaat ttgttatgtt tctgcacatg gttatacgaa
     8341 aattatggca gaagctataa aagcatatat tgaaaaaaat agcgactata aagtaaattt
     8401 atttgatgta atagagcata agcaagaaga tattttagca aaaatatcag tatctcaagg
     8461 tgtattattt ggaacaccaa caatattagg agatgcatta aaacctatat gggatatatt
     8521 agtatcgtta aacccagttc ttcatggtgg aaaagttgct tcagtatttg gttcatatgg
     8581 atggagtgga gaaggtatag aaaatgctat ggagagaata agtcaactta ggatgaaagc
     8641 agtaaaacct tttgccgtta actttaaacc atcaaatgaa gagattgata aattaaattc
     8701 ttatacaggt aagttcctag ataagttaaa cgctactttt ggaagtaaaa agaaaactaa
     8761 gaaatttaaa tgtgtaattt gtaatgaagt ttttgaaggt gatagtgctc ctagtgtatg
     8821 ccctgtatgt ggagctaagg aagaccaatt tatagaaatt gaagaagatg aagttacttt
     8881 tagaaaagat actgatgaat acttcgtaat agtaggaaat ggagcagctg gtttttatgc
     8941 agcagatgca ataagaaaaa gaaataaaac ttgtaagata actatgattt ctaatgaaga
     9001 tgagttaact tactatagac ctgcactttc tgatggtata aatgaagaac ttggctcaga
     9061 tttctatatg gaagataaag cttggtatga taaaaataat atagtagtaa tattaggaac
     9121 gaatgtagat aaattagatg aagtaaataa aactattata gtgaatgatg gagctattaa
     9181 atttgataag cttgtaatag ctacaggaag tagaaacttt ataccaccaa ttaaaggtca
     9241 tgatttagaa aatgtgttta cacttagaaa tataaaagat ttatatagtg taaaagaagc
     9301 actagaaaaa tctaagaaag ttgtagtgat tggtggaggt ttattaggac ttgaagctgc
     9361 atgggaattt agattaaaag gattagaagt agtagtaatt gaagcaatgg atagtatact
     9421 gtcaaagcaa cttgataaag aaggtagtaa aatattagaa caatgtgtaa gagatacagg
     9481 aatagatgta agattaggtg tagcagttga tggtattgaa ggtgatggca aagctcaaaa
     9541 agttatattt aaagatggag atagtgtaga ttgtgatatg gtagtatttt caattggtgt
     9601 aagagcaaac actcaaatgg ctcatgatac atctgtaaaa attgacagag gtattgttgt
     9661 agataagaca ttacagacaa ctgttaaaga tatatatgcc tgtggagatg ttgcacaagt
     9721 ggagaatact agtttagcaa tatggccatc ttcagtagaa atgggaaaaa tagcaggggc
     9781 aaatgcaagt ggagataatt tgacatttga aagtgaagta tatccagttt cattagatgc
     9841 aatgaatgta aaagtattta gtattggtaa tatacaaaat tttgataaag aaatttcatc
     9901 aaaagatgaa gggcaaagaa tatataaaaa attatttatg aaagacgatt cattggtcgg
     9961 agctatactt ataaatgatt taagttgtac tgttaaattg ataagattaa tatctgaaaa
    10021 aggtgatttt gaggatatta tgaaggctga tatactatag tttaaatata ctagaacaaa
    10081 aagtcttaaa atatgacaat tcatatttta agactttttt gttataatat ataataaaat
    10141 aattacacct taactgtaaa tttatataga ttatttactt tttattaata gattcatttt
    10201 ttgagattag tatataatga acatatagag tatataataa tagttaaagt taaaaaaggg
    10261 gaaaagcaat atgcagtata tacaagaatt acttgattta actcaaaatt attgggtgtt
    10321 agccacaata ataggtttgt taagtgcatt tatagaaagc tttataccag ccttaccact
    10381 tgttgctata gttacagcaa atgctgcaat acaaggatta tttgttggat gtttgttatc
    10441 atggattggc tcaggacttg ggacagcttc attattttta ttaataagca gatttaatga
    10501 tagtaagctt tttaataaat tgagaaatag taaaactgaa aaagcaataa gttggatgga
    10561 taaacaggga tttaaattat tatttatagc atatgcctgt ccatttatgc ctggttgttt
    10621 agttactatc gcatcagctt ttggtaaaaa agatgtaaaa gattttgtgc cagcaatgtt
    10681 agcaggaaaa tttgtaatgt ttatagttat aagctatata gcaagtgata tagaaggttt
    10741 tataacaagt cctttaaaga tagcatcatt tatattattg gtgtttttgt catggaagat
    10801 tggaaataga gtaaataaaa atcttgaaaa tcataattat gatttccatc ataaaaaaca
    10861 tcaaagtgat aaagatgata aaatgattta gcttgtacga gataaaacgt atcttaaaat
    10921 gatttagtac taaattattt taagatacgt tttatttgtt gtattaagat ataaaatttt
    10981 ttagctcttt tgtgaagtaa aatatacaaa acttatttgt atttagtttg aaatagtgtt
    11041 acttattgtt tctataacta taataaaata taaaattgat atccaatcaa aaaaataact
    11101 atgaagttta atagcttaga tattaatttt tctgtttttg agttagtttt tataggtagt
    11161 aaagaaatgt ttatagtaat gggataaaac aattcaatac cttctttagt aataaggtca
    11221 agacacaagt gagatagata tcctattata aatccactgg acaaacatga gaaaactata
    11281 ttattgttag tgaagattgt tagagattta aaaaaactat aaataagtaa taaggcaatt
    11341 agactgtgag taaatcctct atgtctaaac ctgcttccaa ataatttgta tattaacgta
    11401 aattttttac ttatataaga acctctcata tctatatctg gaaacaaaga acctaaatat
    11461 gcaaaataaa tataaactat aattaatact attttatatg caatatcgta tttaactagg
    11521 tacagattgt ttataaaggg gagtatcaaa agtgctaata tataacctcc cctttcatgt
    11581 gtttctttta tcatataaaa atcctcctga atcgtcacta taaacattat attggtaaat
    11641 ttagactatc ttttattata ttatatagca aacataagtt tttttcaaaa ggattttaat
    11701 atttaattaa tcttgagatt ttaaattttt ataattttct aaagcaccat tccaatttac
    11761 tgcattaaac cagttgtcaa tgtattcatt tcttctattt tgatatttta aatagtaagc
    11821 atgctcccaa acgtcaagcc ctattatagg agttaggttt ttacttacag ggctatcttg
    11881 atttggagta gtcataatag ataatttccc atctttagta gccacaagcc aagcccaacc
    11941 agaaccaaag acatctaaag cagctttttg gaactcttgc ttaaattttt caaaagaacc
    12001 aaagtctcta tcaatagctt cttttaaaga ttcagaaggt atggtttttt ctggtgtcat
    12061 tatatcaaaa aagaatttat gattataagc tccacctgca ttgtttctta cagctgtggc
    12121 aatatcttta ggtaaagaat ctaaattttg caataattca cataaagaat aattataaag
    12181 ctcaggatat ttctcaagag caacatttaa tttatcaaca taagcttgat agtgtttatc
    12241 atgatgcaat ttcattgttt ctttatctat ataaggttca agtgcatcat atgcataagg
    12301 taatggttta actttaaatt tgttgttttc aggtgtaaaa gcaaatgaag ttatgcactg
    12361 tgaaattata aataaagaca taataactgg tattaatatt tttttcttca taaaaatcac
    12421 ctcctaatat agtatttcta gaaataaaaa aaatatgaaa tattaacaga caatttataa
    12481 gaatttaata gcaatttcat tttaaattga ataagtttta aagccaaagc caaaactatg
    12541 aaatatagaa taagactaaa atgcagaaag gaattttaat tatatggacg gcaatatttc
    12601 aatttattat aaaggtgata tatctaaaaa agaaaatatt aaatttaaaa taaaagaatc
    12661 tctaaataat ataaataata caagagtttc tagtagaata gagtataaaa gtgaggcaaa
    12721 aatttttgat tttgaaagat ttaatgtaat tgatgttatt tatggaaaca aaccatttga
    12781 aaaatatgga aaagttattg tttttaatgg aaatatatat aacaaccatg aaataaaaga
    12841 agaattaatt aaaagagggc acagttttac tacaggtgat gatattgaag tcttattggc
    12901 atcttatata gaatttggta agaattgtgt acataagatt aagggaatgt tcaactttat
    12961 aatctatgat agagaaaacg aaagtatatt tggagcaaga gatttatttg ggataaaacc
    13021 actttattat ataaataagg aaagtgcaat aattttttcc tcagaatata agtttatact
    13081 tgaatatatg aaaaatttaa atataaatga aagaagctta caaagttatt tttcatttca
    13141 gtatgtactt cctgaagata ctatgataca aggaataagg cttataccag caggtcatta
    13201 ttttagggta gaaaatggca tattatcttt aaagagatat aataaacttg aatttagaag
    13261 tagtacaaaa tttttttata ctaaaaatca cttaggtaat agagatgtgg ataaggaaga
    13321 agtaagaaat attgtagtag attcaataag aaatcatatg gaagagcata aagaaattgg
    13381 aacatttctg tctggtggaa tagattcatc tattataact actgtggctt cacaaattaa
    13441 tccaaatata aaatcttttt ctgcaggctt tagtgttaaa ggatatagtg aattggaagt
    13501 agcaaagaaa acagctgata aattaggtat agaaaatatc cagattaata taacgcaaga
    13561 tgaatatata aaagcattac cgaatgtaat ttattctttg gatgacccta tagcagaccc
    13621 ttcagaagta ggtctttatt tcttaattaa agaggcaggt aaacatgtta aagtagcatt
    13681 gtctggagaa ggagcagatg aattatttgg aggatataat atatataaag agtatagtac
    13741 tatgaaatca gttgtcaact cgccgactta tattaaaggt atattaggaa gagtttcaga
    13801 acttatgcca aacataaaag gaagaaacta tctttataga gctacaacac cattagaaaa
    13861 aagatatata ggaaatgcaa aagtttttga aaatagcgaa gtaaaaagat tcttttttaa
    13921 gtataaggaa aagaatatat atgaatacct gttgtctaat ttgtatagag atgcacaaaa
    13981 aaataattac gattatataa gtaaaatgca acatatagat gtgaatacat ggcttcaagg
    14041 tgatatactt caaaaaatta gcaaactttc tacagctgag caggttgaac ttagagttcc
    14101 ttttttatat aaagatgtat ttgatgtagc aaaaaattta agaatggagc aaaaaataaa
    14161 caagaataat acaaaagttt tacttagaga ggcatttaga gaaatagtcc cagaacatgt
    14221 tgttcaaaga aaaaaattag gatttccaac tccaataaga gtttggttaa aagattctct
    14281 gggggggatt gtaaaggaaa ctatctctaa ttcaaatgta gacgaattta tagataaaaa
    14341 atatgtaata aaacttttag atatgcatct taaagggcat agagataatt cgagaaaaat
    14401 atggactata tttacatttt gtctatggca tcaattgttt attgagcata aaaatgtcga
    14461 gtattaatta tgttttcata ttaatcagag ggcaaaaaca tgtactgttt tttccctctt
    14521 gattattatg gaatagtaca aatagaactt tgattgatta gtttactatt tcaataaaat
    14581 tattggcaaa tattttgaca agactacttt ctacagctaa atttaagttt tgtccatcat
    14641 catatccagc agaaatcaat cctagtaagt ttccaaacat atctaaaagt gctcctcctg
    14701 aactaccact agagattgga gctgtaaatt gtatcatttg aaccgtttca aaatcacgaa
    14761 aagctgagat aattccatct gaaactgtat taaaaagacc taaagggctt ccaattgcaa
    14821 ctattttttg acctcttaca ggttttttac cgattttaac aggtattggc ttacattttc
    14881 tatcaacttt tatcacagct aaatcataac ctgaatggta ttttatgatt tggtaagatg
    14941 tgtaaacttt atcatcattt tcaaatctaa ctaaaaatga ataaccatca ttgactacat
    15001 gaagattcgt aagtatataa ccttcattat ttattactac cccagaaccg cttttaaacg
    15061 gtttattttc tttattgcac acaacaatca taacaacaga agctgataac tttgcaagtt
    15121 cttcatagga aagttctact tcctcacctt gtacgatttt tttagatatt aaatttgtgt
    15181 tattaaacgt attttcagag ttaggtttat tcatagggtg ggaagtctta ttggtatttt
    15241 cattgtaatt tatatttgca atatgccttt caaaaggtat ttctaatata tttggagttt
    15301 tcctagaaag ttcaaatata ttagaaaact ttgaacattc aggatataaa tcaagaatat
    15361 ctttatttgg atttatatat aaaatatcac acccaagttg tgataaaaaa tataagaaaa
    15421 aaagttcttg tcttttaata tttccaaaat acaatatctt tggtgaaata ttagtattca
    15481 ccttgttata aaataattta ggtagaaaat attctatcca acacaaaagt ttaactgcaa
    15541 agtttttgat gatagagggt gtacaatttg gcatactcat ggaaaataaa tctaaagtat
    15601 ttttaaatgc aatcttttta gtccaattta aagtatcatt ttctatttta catgggaagt
    15661 tgatattata taaatcccaa ctgttaaatt tagcactatc ataaatatta aaaattttaa
    15721 gcatcttatc tgtttgttct ttgtcaaaat ttatgtttag actgcttaat ctaatatagg
    15781 gaattatagg attattaaaa aaataagtat ctatattttt aattttttct atgtatttat
    15841 caattgaatc atcaacacct atatatcttg taaagtagac ttctttaata tatgaagaac
    15901 tcttattttg ataggtagta ttagacataa attcaattag aggttcattt gattttttta
    15961 ttgaaatctt tagtggttta atagtacaaa tcatattttt tctcctataa taagatgata
    16021 taatctatta taaaacaact taaaacaata tagtacaata attttgtagt ttcaaaataa
    16081 aatatgtact tgtttatata aatgatatat aattacatat taaacatagc ttttatacat
    16141 ttaataaagt atgtaaaatc tatgtaaaaa gtaagaaata taaacatttt tttaattata
    16201 ttttaaaaat atcaagcaag ttttcttcac aaatgaataa aaaatgttat aatatgatta
    16261 aagaaaaaga taaataatta gcaagatttg tttagctaaa attaacaagg gagcgataaa
    16321 ttatgggtat aacattatca aaaggccaaa aggttgattt aactaaagga aatccaggtc
    16381 ttaaaaatat tttagtaggt ttaggatggg atactaacaa gtatgatggt ggatttgact
    16441 ttgatttaga tacagcagca tttttaacag gagcaagtgg aagtgttact aatgatggag
    16501 attttgtatt ttacaacaat ttaaaacata catctggagc agttgagcat ttaggagata
    16561 acagaactgg cgaaggtgat ggagatgatg aacaaatagt tgttgattta tctaagattc
    16621 ctggagaaat aagtaagatt tcttttactg ttacaattca tgatgctaca gaaagaagac
    16681 aaaattttgg tcaagtaagt aattcttata taagaatagt agataaagac acaaatgaag
    16741 agttaataaa gtatgaatta ggagaagatt ttagtataga aacagctata gtagtagctg
    16801 aaatatataa gcacaatgga gaatggaagt ttaatgcact aggttctggt tttgaaggtg
    16861 gtcttgctgc attatgtgga aactttggaa taaacttata atttcaacta taataataaa
    16921 ctaaaggggg atattttcca tggctatagt attaaaaaaa ggacaaaaaa tcgatttgac
    16981 taagggaaat ccagggctta aaaatataaa acttggacta ggatgggata caaattcatt
    17041 tgatagtggc tatgattatg atttagatgt aagtgttttc atggttggag aatctcaaag
    17101 agttgaaaaa gatgaagatt ttatattcta caataactta aaacatccat ctggagcagt
    17161 tgaacactta ggtgataata gaactggtga aggtgatgga gatgatgagg aaatattggt
    17221 gaatttagag gcaatgccaa agcatataca aaagatagct gtaacagtta caatatatga
    17281 ggctgctgaa agaagacaaa attttggaca ggtaagcaac tcatatataa gagtattaaa
    17341 ttctgaaaat gatgaagaaa tattaagata tgacttaggt gaagaattta gtatagaaac
    17401 tgcaattacg gtatgtgaga tatataagta taatggagaa tggaagttta gtgcagttgg
    17461 agcaggattt gaaggtggct tagaagctct ttgtagaaac tatggcttaa atgtttaatt
    17521 taagtaatat aatatattaa atataaataa cctatacaaa taatgtatag gttatattat
    17581 ataaaatttt gtggaggttt agtatgtcga ttaatttatc aaaaggtgat aaaatagatt
    17641 taaaaaaatc taatccggga ctgagtaaca tacttgtagg tctaggatgg gaccctgtgc
    17701 aacaatctgg tggaggcttt tttaaatcgt tgtttggtgg aggacaagct gatatagatt
    17761 gtgatgcatc tgtatttatg cttaatcaag aaggtaaatt aagtggaata aaagatttaa
    17821 tttattttgg aaatctaaaa agtgcctgta agtcagtttt acatacagga gacaatctaa
    17881 ctggtgaggg tgcaggtgat gatgaacaaa ttctagttaa tttggataaa gttccatcaa
    17941 atattcataa attattattt gtagtaaata tatacaattg tgtggataga aaacaacact
    18001 ttggaatgat agaaaatgcc tatataagag ttgaagacca aggtaataag aaagagatag
    18061 caaaatataa tctatctgat aattattctg aaaaaactac tcttatagta ggagctatat
    18121 atagaaaaga tggcagttgg caatttaaag caattggtga aggaacaaaa gatgcgggtc
    18181 ttaaagaagt aatgcaaaat ttagacagga ttgagtgtgc atatggaatt taataatgat
    18241 atcaaatatt ataatgtaga taaagaagaa gttacaaaag acttatctgt taatcctgaa
    18301 aaaggtttat cagaatcaga agttaagact agaagagaaa agtatggttt gaatgaattt
    18361 actccaaaag aagagggtag tttttgggat gacttaaagg aaagtttgag tgaaccaatg
    18421 atagttatct tgattattgc agcagtagta agtgcagtaa ttggggaaac tcatgatgca
    18481 ataggtattg taggtgctat agcaataggt atagcaatag gtatgattac agaaggtcgt
    18541 tctaagaaag cagcagaagc gctttctaag ttgactgaaa acatagaagt aaaagtattg
    18601 agagatgggg aagtacatca aatttctaag agtgaattgg taccaggtga tatagtatat
    18661 attgaaactg gtgacatggt acctgctgat ggtagactta tagaaagtat aaaccttaaa
    18721 attagagaag atatgttaac aggagaatct gatgatgtat ctaaaaagtg tgatgtagta
    18781 gtttctatgg aagagataga atctaaagga gcagtagtag tacaagagcc aatacctgca
    18841 aaacagataa atatggtgtt tggtggtaca cttgtagctt atggtagagg agctctagtt
    18901 gtaacttcaa ttggagataa tagtgaaatg ggtaaaattg ctcaaaacct atcagaaaca
    18961 gatgagcaaa ctccacttca gataaaactt ggaaatttag gtggcttgat agccaaggtt
    19021 tctagtgcag tagcaggatt attgtttata tttatggttt tccaaatggt aagtaagaat
    19081 gtattaaatg tagatatgtc tggaatatta ccatttttag aatcaataga cccagttaaa
    19141 acagcgttta cagtatgtgt tgcgttgata gttgcagcag taccagaggg tcttccaact
    19201 atgataaata tgacacttgc aataacaatg caaaaaatgg ctaaaataaa tgcattggtt
    19261 actaaaaaag aagcttgtga aacgataggt tctgtttctg tgatatgttc agataaaact
    19321 gggacattaa ctgaaaatag aatgactgta gaagttgcat atgttgatgg aagatatatt
    19381 gaaagttcag aagaggaatt aaatagttat tttgaagaaa actgtatgat aaactctaca
    19441 gctgatgtag agcacaatga tggtgatatt aagtatttag gaagtgctac tgaatgtgca
    19501 ttgcttttat attacaaaaa cgtagattat agacaagcta gaaaaaattc taatatagta
    19561 gctcaaaatc cttttacttc agattcaaag agaatgactt ctgttatagg tcaagataat
    19621 catcatgtat tattatcaaa aggagcacca gaagtcttac ttgagttatg ttcacatatt
    19681 caaagaggaa aagacatagt tccattaact gaaaatataa aacatgagat tttagaagaa
    19741 ataaagaaat tgcaaataaa atcaatgaga actttagggt ttgcatataa agaaatctca
    19801 caagctgaag aagaagcagc agtaactgcc gaaagtgatg ctatgaatgt aagtgcaatg
    19861 gaaaataatt tagtatttag tggttttgtt ggcataagag acccacttag aaaagatgtt
    19921 atagagtctg taaatacagc aaataaagct ggtgtttctg taaaaatgct tacaggggat
    19981 aatataaata cagcaagagc tataggtgaa gagttaggtc tattaaaaaa taatatgagg
    20041 gtggttgaag cttcatatat agatacgtta gatgatgaag agttaaaaga agagatacaa
    20101 agtatttcaa tcgtggcaag aagtaaacca gatagtaaaa tgagaatagt ttcagctcta
    20161 caaaagagcg gagatgttgt tgcagtaacg ggtgatggta taaatgatgc tccagcactt
    20221 tcaaaagcag atgtcggtat agcaatgggt atatctggta cagaggtatc taaaaacgca
    20281 gcggacataa ttttaactga tgatagtttt agtaccattg taaaaggtat taaatggggt
    20341 agaggaattt atgataactt ccaaagattc gttcaattcc aattgactgt aaatgtaatt
    20401 gcatttttag tggctataat atctcaagtt atgggacaag agatgccatt tactacaata
    20461 caattattat gggtaaacat aatcatggat ggaccaccag cactagcatt aggtctagaa
    20521 ccagttagag accatgtatt aaatagaaaa cctgttgata gaaaagccaa tataatttct
    20581 aagtcaatgg tgtatacaat agtattaaat gcattctata taacagcaat actaatgcta
    20641 caatctacat ttaatttctt aggagttgac gaagctcata agggaacagt aatgtttgca
    20701 ttatttgcct ttagtgcact gtttaatgcg tttaactgta gagaatttaa tgcagatagt
    20761 attttcccta attttacaca taacaaatta gcactgcaaa taatagtatt gacaggaatt
    20821 gcacaagtaa tatttactca gttattccaa gatttcttta actctgtagc aatggatttt
    20881 atgacatggg taaaagttct atgtgtagca gcaagtgtaa ttgtggttaa tgaagttgta
    20941 aaatgtataa taagactggt aaaaccaaaa aagactgctt aaaacaaatt ttttagaaga
    21001 gaacagactg actcaaaata tgaattttgg gtcagttctg aataaacatt taaattggga
    21061 ggatagttat gggtgactca aaggtatttg aaaaaatatt ctccagccaa tcagatagag
    21121 gaaattatac tccttcaaag ggatatctaa gttattttat ttcatatatt ggtttagaag
    21181 atgaagtttt atacaatctc gagatattta agacaaaaca aaatattgat agcaaaaaag
    21241 atattgcttt atttactgat gttatagcaa atcctagtga ttttgatatt ataaattatt
    21301 ttaaaaatgg acttcaaaaa tatagaacta gtatggaaga tgtagatata aatattttag
    21361 gatttgaaga gattgattat aaaataaagc aagcaatgga taaagtgtta aaagaggaag
    21421 aaaaagaatt tactaatgat agagttaagc aaaattttat agtgaaaata atggcatgga
    21481 taaaaattta tatcggtgct ttagatataa ataaaaatga agctccaaaa gtaatatttt
    21541 atggagatat aaaaaaacat gaagtttatt tactcttaat attgtacttg gcaggttttg
    21601 atgttttata tcttaatcca aattcaaaga gtaatataga tattttaaaa tcagaaagat
    21661 acaatgtaga atttgaagaa gccaacataa tagaagaaaa aacttctttt gaagaaaggg
    21721 ttattttagg tgaaaaaata gataaaagtt ctgtaaaaaa agcttttact gttggggcag
    21781 aagcatcaaa acgtataagt gaggaattgt taaatgatgc aggatttata aaaccttggc
    21841 aacttcaaga tagaaaaata aaaaatctac ttctaagttc aaccgttgat gaaatatcaa
    21901 tatactggaa tcagccactt aaattaagac caggatttaa ttttaatgat gctattgtag
    21961 aagctccaaa ttttctttct aagattaatg gaatatataa tgataagaat gaatatatta
    22021 agtttttaga tttattaaga gattcggaaa gttcaacgtt tattgaattt aatggagatg
    22081 tagatagatt ttcaaaagct tttacaagag aagcttttag tttatccttt ttattggatt
    22141 caaaaggtgt aatagataaa aactctgttt taaataataa agattattcc atatcaacac
    22201 tagcattaaa tcaacaaatt atgattttag aaaaagtgga agagttatta gaaggaagta
    22261 tgtttttgaa tggtttaagt ggagaagaca agataaaagg tctatttaca gtacttcaca
    22321 tggataagaa gtttgttcac atgatgaaca attttgatta ctcacttata aatccaaaat
    22381 tgattatata tatgtataag agtattatat ttgataaaga aatagttttt cttatgcttt
    22441 tacttagtaa gattggattt gatattatta tcctgtgtcc aggaggagaa aataatatag
    22501 agaatgttat aaataaccaa ttgattgatg tacacagatt ggataaaatg gtatatgacc
    22561 ttaaattaaa ttcgcttgaa aatgatatac ctttacttaa aaaaattttt ggaaagagga
    22621 gacgatttta gatggggata aatataaata gtttttcaaa agataagaac tctgtagatg
    22681 ttactgagaa tttgcccaca gcagttcaag aagaaaattt cgatataatg gaatatacaa
    22741 ataataaaaa aaatgaattg agaaagtcta aggaagttga ggcattgact tctcttatag
    22801 aagtagaaaa tccagacacg attttacagt ttggtagaaa agcatctgaa ggagtagcaa
    22861 gagtttctga tagcctttta aatacaataa aattaaatag aaatgaagaa aattctaaaa
    22921 tgttggttca tttaactaaa ataatggaca agtttgattt agatgatttt caagagacta
    22981 aggaaccaaa tttcgttcaa aaacttttca aaaaagctaa taacgccatt gaaatgatgt
    23041 ttcaaaagta tgaaacatta ggaggagaag ttgaaaaaat tcaaattgag cttgagcaat
    23101 acgaaagaga tatagcgctt tctaataagc aaataggtgc tatgttaaat gaaaactttg
    23161 agttttataa tgaacttcaa aaatatattg ttgctggaga aatggcaata gaagaaatgg
    23221 ataatgagat actacctttc tttaaacaaa aatcagagac tagtggagat caaatggatg
    23281 ttgttaatta tcaagaacta ttaaaagttt atgatatgtt aaatcaaaga gtctatgatt
    23341 taagaatagc agaaaatata gctattcaaa caatacctat gcttagaggt atgcaacata
    23401 ataattatgg tttaattaga aaaataaata gtgcatttgt tgtaacttta ccagtattta
    23461 aacaatgttt atctcaagct atattactta aaaagcaaga attacaagca aaatctctaa
    23521 aagcacttga tgacaaaact aatgaattat tgcttagaaa tgcacaaaat gtaagttctc
    23581 aaagtgcaca aatagctaga atggctggaa caagttctgt tcaaatagaa acattggaaa
    23641 agatgtacaa tactatcaag tctggtatag atgaaactat gagaatagaa gaaaacaata
    23701 gagctttaat taaagataat acaaagagat tggaagaatt aaatacaact ataatttata
    23761 ataagtagta ttatattaag ggctaattta tataaagttg gccctttcta tatatgagga
    23821 ggctagacat tgaaatattt cgattatatc tgtaaagatg atttggagag aatttttttg
    23881 aaagagccag aagactttag tgctaagact gaaaaagatg tactgaaata tgcactggga
    23941 gcttttttat acgttccagc aactcaatat aatatgattt ataagagtat tataggggat
    24001 gttaagggag ttagaccatt agctatttgt ttagaagatg ctgttggagt aaatggggag
    24061 ttagaggcta tagaaaacct tagattaatt ttaaaaaata ttagcaatga aagtataact
    24121 aataaagatg gaataccact aatttttgta agaataaaag atgtggagca actgttgaga
    24181 attaaagaga ttataattaa aaatagtcat tctataaccg gaatattaat tcctaaagca
    24241 aactcggaat taattgaaaa ttgtatagaa gctttagatt ctatgaatct tcaagatatg
    24301 tatgttattc caataataga gacaagagaa tttatatata atgaaaaaaa agaacttagt
    24361 tttattaatt tgtacaatgc tattttaaga cataagtcaa gaatattaag cattagagta
    24421 ggtataactg atatattagg gatgtatggt ataaggagag ataaaaactt ttctatatat
    24481 aataatttga tttgttcttc atttatacta gatataatca catatcttca aagaccagag
    24541 ctagatatac ctataagtgg tggagtgtca gaattttttg atatgaaaaa taaggacata
    24601 agaaataagt atatagaaga aatattatta gataaatatc atggattaat tggaaagact
    24661 gtaattcatc caatgcaaat tcaaattgta caagcgttat ctacagtatc atatgaagat
    24721 tttactgatg ccttggatat attggatagt acagacagta aatatggtgt gagtaagggt
    24781 gtgttaggag agagaatgaa tgaaataaat ccacattttt tatgggctaa aaaaacattg
    24841 attctatcta aaatatatgg tgtattaaat gaaggagtag actatgaaga attgcttaaa
    24901 ttttaattgt gagattgaca ttattgataa tccattaaat ttagaactaa atgatttttt
    24961 agacatagga ataagaaata atagcaaaag acgttttttg tttatctcaa agaaacttgg
    25021 taagcattta gcatgtaagc caagtgagat ggataatttg ggaaaattaa tagctacaat
    25081 ttataatgaa aaaaataagg aggaatcaaa tggtactgtt atagcttttg ctgaaactgg
    25141 tacagctgtt gggcatagtt tttttgatta tttatgtgga gattatgaat ttattcatac
    25201 tactagagaa cagtttgacg agttagaaaa tctggaattt ttagaagaac attctcatgc
    25261 aacagaccaa aatttatact ttggtatgct taacaacttt aaatttggag atgagataat
    25321 attggttgat gatgagatta ccacagccaa tacatgcatg aacataatta ggaagattca
    25381 aagcatctat cctaaaaaga aatacactat atgttcaata ctcaattggg taagtgatga
    25441 aaatttaagt aaagttactc gtttagaaag agagctagat tgtaagatag attttgtata
    25501 tttatttaaa ggaaacttta aattttatat agatgaagat attatttcaa attataacga
    25561 taattatact attactaaat tagatactat tttaagtgat aaagtaaatt tagtagtaaa
    25621 tcatatttat gttgatttag aagattacat tggaaataag aaatatgtaa aatatacagg
    25681 aagatttgga attaatagaa gagaacaatt tagattaaaa gaaatcgtta agagagaaag
    25741 taaaaaaata actatagaca ataaagaatc tttaaaaaat gaaaaagaaa agattctatt
    25801 tttaggtact gaagaattta tgtatatacc tatgctgttt gcaaaagaaa aagaaaatca
    25861 atgtgatgta tactatcatt caacaacaag aagtccaatt attaatattg ataagcataa
    25921 ttatcctatt agaagtaaat ttatgctaaa gagtttttat aatatggata ttcaaaatta
    25981 tatttataat atagataaac agaatttttc taaatgttat ttatttgtag agctaaataa
    26041 aagtgaaaat tcttatctag agtttattga tataattaaa aagacaagta taaaagaatt
    26101 aactatagta tgttgtagct agagtgtttt aacaggataa aatatatcac gattttaaga
    26161 taggagttga gtcatatgag agattttagt acgtattcta aagatgatgt tattttttta
    26221 ttaaaagata tatcaaattt aattgaagaa gaaggaaata aagaaagaga attaaaaata
    26281 caaaatggta gacattattc agaaatgata ccaatagagt atgaagttag tgaagattat
    26341 ctgaatttat atcatgagaa actaagagaa aataaagata agcttgcatt ttctataggc
    26401 gttatgtgtg aaaaaataat taaaaaaaat ggaaatgatg tagtactcgt ttcacttgct
    26461 agagcaggaa cacctattgg tattttggca aaaagatatg taaaaagcaa gtataatata
    26521 aatttacctc actatacaat ctctataata agagataagg gaatagatat gaatgcaatt
    26581 gaatatatag taaagaatca tccgagctca aagattcaat ttttagatgg atggactggt
    26641 aaaggaacta tatcaaaaga acttgaaaaa gcatgtgatg agcttaatga taaatttaaa
    26701 aaacattttg actcaacact tgctgtatta gctgaccctg ctggatattc aggactttat
    26761 ggaattagag aagatttctt aataccaagt gcatgtttaa attcaaccgt ttctggtcta
    26821 gtaagcagaa ctgtactaag agaggattta attggtaaaa atgacttcca tggagctaag
    26881 ttttatagac atttaaaaga taaagatgag tctatgaact atattgaaac tatagaagaa
    26941 tgttttaaaa atcaatttaa gaacatatct gatgaagttg aaaactggga aagtgatatt
    27001 ataacaagag atggatactt tgatgtttta aatataaaag aaaagtataa cataacagat
    27061 attaacttta tcaaaccagg tgtaggagaa acgacaaggg ttttacttag aagagttccg
    27121 tataagattc ttgttaaaga cttaaatgat aaatctttag accatatatt cgtattagct
    27181 aaggagaaaa atgttgaagt tgaacaaatg gatttaaaag cctataaatg ttgtggaata
    27241 ataaaaaata tgaaagatgt ttaggaaata tattagacag gagaatattg aatgattgtt
    27301 ttttcagatt tagacaggag tatcatttac tccaataaat ttttaagtgc tgatagtaaa
    27361 tatgctaata tagaaattta tagggaaaaa gaaatatctt atatatcttt agatactata
    27421 aatttaataa agcaaataca atattatggt atgtttatac ctacaactac tagaacagtg
    27481 gagcaattta agcgcataga gtttaataaa tatgggattt attttccttg gagtataact
    27541 tcaaatggag gagttatact taaagataat gaaatattga aatcatggag tgaaaaaata
    27601 gataaactaa aatctgacta tgagcccatt gaaagcatga tttataaatt taaagactat
    27661 ttgaatgtag atggaataac taattttaaa gttgcagaag atacattttt ttatatagtt
    27721 gttgatttct caaaatttaa tttagaatca attaaagaat atacaaatgt attggaatca
    27781 aaaaattgga agttttatgt gagtggcaga aaaatatatt ttataccaaa agaaatttca
    27841 aaagaaaatg ctataaaata cttgaccaaa gaattaggaa tagaatattt ttatgcaatt
    27901 ggcgactcta ttatggacta tggtatgctt aatatctcaa ataaagctta tctattgaag
    27961 catggtgata taaataaaaa tgaaatagaa aattcatttt tatcaagttc ttttaatgga
    28021 atgagtggaa ctgaagagat actatccaac attttagatg aaaactgtct acttaatata
    28081 taatgactga tatataaata ataagctaga aaaatctgaa ataaattaga ataaagttta
    28141 tcatactaat ttatttcaga tttttatcaa tttatattta agtaagaact caatatgtta
    28201 aaatgaaggt ggtgtcattg cccagactga gatacataca tcatcatcat aattttcata
    28261 tacatgtggg atagtactgt taaaataaaa actatctcct tcttccaata gatattcctt
    28321 atttccaagt gttatcttca ttttaccttt tattatatag ccacattctt ctccttcatg
    28381 tgttacaaat tcactgtttt ttgtgtatga ccatctaaag taacaagtat aaattctatt
    28441 tttttcccag ataaattagg aacaagaagt tcgtaaaatt ttgtagaatc attagttact
    28501 attttttttc gattattttt ctttactact atatcagagt cctctcttcc aatctcttca
    28561 aaaaaataac ctatatttat atcgagggct tttgatattt tccacattgc tacaatagat
    28621 ggaacaacca tattacgctc aatttgactt attaagcctg tacttaaatc tgaatttttt
    28681 gctaaagtag agatacttat atttttagat tttctaagag atctaatttt gcttccgaca
    28741 tctatattca ttagatacaa acctcctcag acatgattat aacatataat ttataaagat
    28801 taataaaata aaaaaagttt tataatacat gtattttttc tgttatattg aattttctga
    28861 aaagatgcat tataatagta ttaatattca atatattgaa tattgatatc gatattttaa
    28921 tttaatgaaa tggaggtagt taagatgaag agttttgtaa gtcctgataa tatttgggta
    28981 ttatgggcag ttgtaactgg atgggcagca tttagtattt atttggaaca aaagtacaat
    29041 tgggcatcaa aagtgtctgg agcaataata gctcttgtag gagcaatgtt attatcaaat
    29101 ctaaatatta taccagtaga gtctgttgta tatgaccaag tatggggata tgttgttcct
    29161 ttagccatag ctttattgtt atatcaatgt aacattaaaa agatatggaa agaaagtgga
    29221 agattgctca ttatatttct tgtaggttct gtgggaactg tacttggagc tatgattgga
    29281 tttttagcat taaaaaatgt agtaccagat ttaaatattg ttgcagctat gatgacaggt
    29341 tcttatatag gtggaaatgt aaactttgcc gctatgtcag gggcatttga tgcgccagga
    29401 gaattagtat cagcaacagt tgtagcagat aatcttttaa tggcattata tttctttgtc
    29461 ttaatagcta taccatcaat tggatttttt agaaaacatt ttaaacatcc acatgtagat
    29521 gaaatggaaa gtataggtgt aactgaagga gaaacagtag cagcaaatta ttggggaaga
    29581 aaagaaatat ctctaaaaga tatagcaata gccattggta gtgcctttat aattgttgct
    29641 gtatctgtag aactatcaac ttggttcaaa gctataatac cattatcaaa tcctttttta
    29701 gcaatgttaa atactttatt tggaaatcaa tatctaataa taactacttt gactatgttg
    29761 tttgctacat ttatgcctaa tttctttggt gacataaaag gagcacagga gttgggtaca
    29821 tttttaatat atatattctt tgttgtagta ggcgttcctg cttcaataac attaataatt
    29881 caaaaatcac cattactact tttatactgt ggaataatgg tactaataaa catgctagtt
    29941 acatttatag ttgcaaaaat atttaagttt agtttagaag aagctattct tgcatctaat
    30001 gcaaatattg gtggacctac aacagccgca gccatggcga tatcaaaagg atggtctaag
    30061 ctagtagggc caatacttat agttggtaca tttggataca tagttggtaa ttattttggt
    30121 cttttagtag gaaacatttt gatataattt tacgtgaaaa aaagttgttt tttagaaaga
    30181 tttttattta attggaggtt gttatgattt tcgatggaca ttcagatact tgggcagatg
    30241 taacaataag aaggcttaat ggggaaaaag atgtatttag aagaatccat cttgataatt
    30301 ttaaaagagc aaatatagaa ggagctattt ttgtaatatg gatagacccg ccatatgata
    30361 aagagcctga aaaaagagtt aaacaaatca taagctctat aaaagatgaa attgaagata
    30421 tgaaagatgt tgtaaatata gtaaaaaaat attcagatat agataaaggt ataagtgaac
    30481 ataaaataaa tattttaatt ggtcttgaag gattaagcca tattggaagt aatatagatt
    30541 caatagatta tttttataaa gaagttggtg caagacatgc atcattaact tggaatgaac
    30601 agaatgaact tgctacaggt tgtttaggag atgaaaatag gggtttaact gaaataggta
    30661 aaaaagcagt ccataaaatg gaaaatttgg gcatgatagt agatgtgtca catttaaatg
    30721 aaaaatcatt ttgggattta atgtctattg caagtaagcc agttatagct tctcattcta
    30781 atgctaagag tttatgtgat gttaaaagaa atcttacaga taatcaatta aaagaaattg
    30841 caaatacagg tggattagtt ggaataaata gttttagagg atttactaat agtaatccta
    30901 agaagcaaga tttaatacat ttggttgacc atatagatta tatggtaaat cttataggta
    30961 tagaacatgt atcttttggt tttgatttta gtgattactt ggggaaagag accataggtt
    31021 ctttcactgg aaactctagt atgccaagtg tagatggtct tgaaagcaca catacagcac
    31081 ataacatagt agtagagctt gaaaatagag gttataaaaa aagagatata gatttaatct
    31141 ctagtggtaa tttttataga ctctttaaat atatactaaa ataatataat aaaaaactta
    31201 aatttat
//
LOCUS       DAMKOJ010000045        31137 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000045 DAMKOJ010000000
VERSION     DAMKOJ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31137
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.047"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(173..2143)
                     /gene="ftsH"
                     /locus_tag="PC592_002168"
     CDS             complement(173..2143)
                     /gene="ftsH"
                     /locus_tag="PC592_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF4056138.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(2177..3565)
                     /gene="tilS"
                     /locus_tag="PC592_002169"
     CDS             complement(2177..3565)
                     /gene="tilS"
                     /locus_tag="PC592_002169"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDF4056139.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERSEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVSEE
                     IEFYYNIPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(3748..4176)
                     /locus_tag="PC592_002170"
     CDS             complement(3748..4176)
                     /locus_tag="PC592_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDF4056140.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVV
                     YKEKEENIEITNTIKILKNEVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RKLDINIQEGEHIKLKIDYNINVQDLFLGRNKIDIYIDTK"
     gene            complement(4193..4999)
                     /locus_tag="PC592_002171"
     CDS             complement(4193..4999)
                     /locus_tag="PC592_002171"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDF4056141.1"
                     /translation="MSNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKV
                     LEVKNIINNTEIHGTYQYYVSDIPEKFTDIAREFLKKKIDRIQKVEIQKY"
     gene            complement(5201..5686)
                     /locus_tag="PC592_002172"
     CDS             complement(5201..5686)
                     /locus_tag="PC592_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HDF4056142.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTAKIEKINKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(5737..6396)
                     /gene="spoIIR"
                     /locus_tag="PC592_002173"
     CDS             complement(5737..6396)
                     /gene="spoIIR"
                     /locus_tag="PC592_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HDF4056143.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILENGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVIEVVKDLEKK
                     F"
     gene            complement(6542..7258)
                     /locus_tag="PC592_002174"
     CDS             complement(6542..7258)
                     /locus_tag="PC592_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4056144.1"
                     /translation="MLLIAVKKGLKFVENLTKLNLDNYKPLRDVVFENLREAILEGKL
                     KPGQRLMEVQLAEQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLE
                     VRASLEGLAAYLAAERISEEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKA
                     TNNKKLIQLINSLWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYAT
                     EHIEKAEQFMIDKAMISKDL"
     gene            complement(7206..8096)
                     /locus_tag="PC592_002175"
     CDS             complement(7206..8096)
                     /locus_tag="PC592_002175"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDF4056145.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELEEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNQLWKLRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTSIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTISKHKEISDIKQIMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(8214..9764)
                     /locus_tag="PC592_002176"
     CDS             complement(8214..9764)
                     /locus_tag="PC592_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF4056146.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(9857..10123)
                     /locus_tag="PC592_002177"
     CDS             complement(9857..10123)
                     /locus_tag="PC592_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDF4056147.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(10271..11131)
                     /gene="yabG"
                     /locus_tag="PC592_002178"
     CDS             complement(10271..11131)
                     /gene="yabG"
                     /locus_tag="PC592_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HDF4056148.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(11215..12153)
                     /locus_tag="PC592_002179"
     CDS             complement(11215..12153)
                     /locus_tag="PC592_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HDF4056149.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMATKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLNKFYDLGVRMMTISWNHVNELSFPHNKLEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDEIEKIYYKNALRVIKEVL"
     gene            complement(12263..12424)
                     /locus_tag="PC592_002180"
     CDS             complement(12263..12424)
                     /locus_tag="PC592_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056150.1"
                     /translation="MFILRFADDDDNLSVKDFKSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(12434..12931)
                     /locus_tag="PC592_002181"
     CDS             complement(12434..12931)
                     /locus_tag="PC592_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF4056151.1"
                     /translation="MSLYTEWRNLSDNHENQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEDVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(13046..13756)
                     /locus_tag="PC592_002182"
     CDS             complement(13046..13756)
                     /locus_tag="PC592_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HDF4056152.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNNVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWIKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYNVDINNIKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFGLDVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     DQEYAIKVLKELFNYDII"
     gene            complement(13929..14459)
                     /locus_tag="PC592_002183"
     CDS             complement(13929..14459)
                     /locus_tag="PC592_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056153.1"
                     /translation="MDIRALPTKITKEEAIDIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIVTLKIHKTKSIFKSRRYSNGVNELKILVNGSTGSGSIVQDFPTYEIIKNVDCN
                     IVQYSDKDERRVKAKANKIAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(14476..14706)
                     /locus_tag="PC592_002184"
     CDS             complement(14476..14706)
                     /locus_tag="PC592_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056154.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGRIIPYGVMAVVIIIFFDYIYRVSKMTRKK"
     gene            complement(14721..16115)
                     /locus_tag="PC592_002185"
     CDS             complement(14721..16115)
                     /locus_tag="PC592_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF4056155.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWRIDKELIGLIMVGI
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(16241..17494)
                     /locus_tag="PC592_002186"
     CDS             complement(16241..17494)
                     /locus_tag="PC592_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4056156.1"
                     /translation="MENKSNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALSLS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGALGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGLLLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKSLNNKIA"
     gene            complement(17545..18699)
                     /locus_tag="PC592_002187"
     CDS             complement(17545..18699)
                     /locus_tag="PC592_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF4056157.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKDAMKPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEEKVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(19260..19832)
                     /locus_tag="PC592_002188"
     CDS             complement(19260..19832)
                     /locus_tag="PC592_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4056158.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFARKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSIQ"
     gene            20035..20262
                     /locus_tag="PC592_002189"
     CDS             20035..20262
                     /locus_tag="PC592_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF4056159.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(20482..21225)
                     /locus_tag="PC592_002190"
     CDS             complement(20482..21225)
                     /locus_tag="PC592_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF4056160.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEQEYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILSLMGFANNFGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDSGIVIYFGVDEIAPESFGIPKFKLKFSD
                     FGNFINSRFYCISPDIYVQSRGRVKYFMG"
     gene            21392..22264
                     /locus_tag="PC592_002191"
     CDS             21392..22264
                     /locus_tag="PC592_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF4056161.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGNYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGYIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            22264..22929
                     /locus_tag="PC592_002192"
     CDS             22264..22929
                     /locus_tag="PC592_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF4056162.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKNHKDAKEAELNYNVLNFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEIYHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            22950..23807
                     /locus_tag="PC592_002193"
     CDS             22950..23807
                     /locus_tag="PC592_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4056163.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIGLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSAKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKYITEISAGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(23944..26490)
                     /locus_tag="PC592_002194"
     CDS             complement(23944..26490)
                     /locus_tag="PC592_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056164.1"
                     /translation="MNIFNKVALQGLKKNRTRTFVTIIGVVLSAAMITAVTTFGVSLM
                     NYMINGAIIKYGDWHVEFLDVDSSFVQEQRVNDEVENTVTFENIGYATLEGSRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSGKVATDGGVKFAVGDTISLDVGKR
                     MSENENLGQSDPYTAGSEAFIPQNKRTYTVVGICRKPVFEESSAPGYTLITKEDEQVK
                     ADSLSLFVTLKNPRHVRSYTSSAREHDYIFNDNVLRFMGISDNNLFNMFLYSVGGVVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGVIGIPIG
                     VVIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIVVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQQIYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVKDLKQMSNQRSEVTDQDIIFSTQGMKDSEMLKLYDKLKTASGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYNGLHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPTEEYTGQNAKMIAVSMLTKDNHIIDIFTNSSMDVSLTPEVNGKLDTPERQNVNIS
                     FVKVVPPDSPPGIRNSDMKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     SEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWVSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(26490..27176)
                     /locus_tag="PC592_002195"
     CDS             complement(26490..27176)
                     /locus_tag="PC592_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056165.1"
                     /translation="MAFLKIENLCKVYGKNENQVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(27259..28248)
                     /locus_tag="PC592_002196"
     CDS             complement(27259..28248)
                     /locus_tag="PC592_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4056166.1"
                     /translation="MFRNREFRRFAILFLLITILTVALGFAISTMTGIISIVSATTFG
                     TAFFVFTKNRYKSIAQISEQINLVLHNANHLYITESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIQ
                     MDWLITSLLKLSRLDAGIVVFQKEEIDVDNLISSALHQLLIPMELHNITLHINIPKGV
                     KILGDLNWLSEAIQNIFKNCMESVGDNGKIDIVCEDNFLFTQLTIHDNGEGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAENHPQGGAIFVIRFPK"
     gene            complement(28235..28921)
                     /locus_tag="PC592_002197"
     CDS             complement(28235..28921)
                     /locus_tag="PC592_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056167.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKENQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(28918..29055)
                     /locus_tag="PC592_002198"
     CDS             complement(28918..29055)
                     /locus_tag="PC592_002198"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056168.1"
                     /translation="MEVLCIDCIRTKETNENCVIISKIVVYYYSAGIYKTNKIKEDES
                     K"
     gene            29339..29668
                     /locus_tag="PC592_002199"
     CDS             29339..29668
                     /locus_tag="PC592_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF4056169.1"
                     /translation="MDLNKEVLKGHIDTLILSILNKGDSYGYEIAKIVINETTFELKE
                     STLYVSLKRLESKGLIKSYWGSDQGLGSRRKYYNITDEGKENLELKIQEWNFIQSVMN
                     KFLKRGE"
     gene            29673..30122
                     /locus_tag="PC592_002200"
     CDS             29673..30122
                     /locus_tag="PC592_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056170.1"
                     /translation="MKIIEEYLEALYKNDTSKEIQDLKEELKEHLIDSTNEFIENGYD
                     INEAQNKAIERFDGSNGVSVELRSIFKQKIEPKKVLLRKLSNSRIVFLNLFGWLLAAT
                     AYTINRGFGHIAPPWIIILLIISIVILIILTIIIKGLKKEIENDYNI"
     gene            30189..30566
                     /locus_tag="PC592_002201"
     CDS             30189..30566
                     /locus_tag="PC592_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF4056171.1"
                     /translation="MVKKILLEKFLDTSGVSYINEKLNLFKDTKWISFGTYIMTVDSF
                     CYREDSKHYNPIMSTFDYESEIFIVNALYKENIYSIKSKKLYRNVSKGDKIIVTIKYS
                     YDKYENLIHEEIHDYHLYPLSLD"
     gene            complement(30751..>31137)
                     /locus_tag="PC592_002202"
     CDS             complement(30751..>31137)
                     /locus_tag="PC592_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF4056172.1"
                     /translation="VVLATVNNHDKDEFIEIAKDMKELGYTFVATEGTAKSLRENGIE
                     ADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRTAIEFSTEIMTSL
                     DTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT        10268 a         5567 c         3593 g        11709 t
ORIGIN      
        1 atttatgtga ttttatattt tatttaaata attttaaaat aataaaaaac tgaaagtatc
       61 aatcaaatta atacatgcaa atatactttg cttattaatt taatattata ctttcagttt
      121 tagtatttaa tccatatcag ataataatct taaaatgacc aaagtcttaa aactatttat
      181 ctttatcaga tttatcttct aaatttttat ttatatcaat aacattgttt ctttcttctt
      241 catctttttc taattttata gttaattgct cttcaacttc tttagaagaa ttttcctctg
      301 taactgcatt ttcaatttca ttcagaggta actctttatt aaatgctttt acaaattgtt
      361 ctgcatctag agtttcatat ataagtaaag cttgtgccac atattctaat ctatccatat
      421 tttcttgtaa tatacttctt gtcttatcat atgcaccatc aactatacgt tttgtttcct
      481 ggtctatctc aaaagcaact tcttcagaat aatttctctt acttgaaaaa ctattaccta
      541 ggaatacttc atcatcactg tcaaatgaca ttggaccaag tttagaactc attccatact
      601 ttgttaccat acttcttgca gtagctgtaa ctctttctaa gtcatttgaa gcacctgtag
      661 atacatcctt aagtactagc tcttctgcta ctctaccacc aagtaaaact acaatatttt
      721 ctttcatttc attttttgta gcatagaact tatcttcaac aggaagttgc attgtaaacc
      781 ctccagctct tcctcttgga actattgtaa cttgatgaac aggacttact tcttcaagta
      841 catgggcaca aactgcatgc cctccttcat ggtatgctgt aagtcttctt tctttctcac
      901 ttattacttt agatttttta gccacacctg ctataacctt tgttatagct tcttctatag
      961 tttccatctt aattttcttt tctctttttc tagcggttaa tattgcagct tcattcatta
     1021 aattctctat atcagcagga gtaaatcctg gtgttcttct agccaagaca tccattttta
     1081 catcatcact taatggctta tttcttgagt gaactttaaa tatagcttct ctacctttta
     1141 catctggtgt accaacaaca acttgtctgt caaatcttcc tggtctaagt aacgctgggt
     1201 caagtatatc tggtctattt gtagctgcca taattattat accttgattt actccaaatc
     1261 catccatttc aactaggagt tgattaagag tttgctctct ttcatcatga cctccaccaa
     1321 gacctgcacc tctttttcta ccaactgcat caatttcatc tatgaatatg atagctggag
     1381 cacttttctt agcctgttca aataaatctc ttactcttga agcaccaacc ccaacaaaca
     1441 tctcaacgaa atcagaacca cttatactga aaaaaggaac tcctgcttct cctgcaactg
     1501 ctcttgatag atatgtttta cctgttccag gaggccctac cataagcatt ccttttggta
     1561 ttcttgcacc cagttcaata tatttcttag gattctttaa gaaatctact acctcttgta
     1621 aatcttcttt ttcctcatct agtccagcta catctttaaa tgtaactcta gttttttcat
     1681 catctttatg aaccttagct tttgatttac caaagctcat aacctttccg cctccacctt
     1741 gagactgatt cataaacacg aaccaaataa tcaccataaa gaatattaac agtaatgtag
     1801 gcaacatttc gacaaaccaa ggtgtagatg gcttagcttc accaccaaaa gttagtttcc
     1861 cagccttagc ttggtctaac acctcatctg caagtttatt tcccatcact tctgttggaa
     1921 catacgactt aaactttgta tttgtatctt ttatagtacc ttctacagaa gtttgattta
     1981 caaagtataa tcttgatata ttctcatctg ttaattctct atatacttca gagaatttta
     2041 aatcttttat tttttctgta ggcttacctg agaattgaac tatacctact ataattataa
     2101 aaacaagtag ataaaaacct gcccctttta gcaacttatt caatatagaa gccctccttt
     2161 catacattgc tttgccctat aatttgttaa aattaatttt taatacttct tttgtgtttt
     2221 catcaatttt ataattttca ctgattttat aatctccaac acatattatt ccttcactat
     2281 ctgtgattat aggaatttta catctttctt ctcttgggat ttttaaatct atgaataaat
     2341 ctttcacttt tttacttccc atagcaagct ttatcttatc accttgcctt ctactcctta
     2401 ttactatacc cccttttacc ttattaaaat caaacccttt agatgaattg tctaatttca
     2461 tactcttata cctatctata ctcattactt gggtctcaat aatttgtttt aattctttta
     2521 ttttaataaa cccattacta ggtatattgt aataaaattc aatttcctca ctaacaattt
     2581 cctcattcgt taatattata ctgtcttttt ttctataaac aaatatattt cttggaagag
     2641 ttaacatttt atttactttt gaattatctt ctaaagacat tatatcctct atatgtcttt
     2701 ggtcaacaaa attagtatct cctagtatat gttttataga atttctaaga accctaactt
     2761 tgatagcatc atgtaagcaa acaaaatcgt ctaaatttat ctctacaaag cctttttctt
     2821 ttatatttga aacttctcta aatttagctt ctgcctcttt ctcaatataa tcgttatcac
     2881 tttttaaact attgctcatc ctcactatag attctattac atttgaatta aaattatcct
     2941 tcatatatgg taaaaggtct aaccttatct tatttctagt gtatatattt tctaaatttg
     3001 ttttatctat cctcggattt aaattataag cttcacaata ctcctctatc tcacttcttt
     3061 ccacatctaa tattggtcta attatgcaat tatctctaat atagtcaatt ccctttaaac
     3121 cttttaaacc tgttcctctc atgatacgca tcataacagt ttcggcttgg tcattgagat
     3181 tatgacctat tgctatttta ttagctttaa tcttatcttt gatttcataa aacatttcat
     3241 atcttagctt ccttgctcct tcttctaatg ataatccctc attttcacaa tattttggta
     3301 cattaataga ctttacaaag aatataattc ccatatcctc acaaagttta gatacatata
     3361 atgcatcttt ttgagcttct atccctctta tttgatggtt taaatgtgct gcatatattt
     3421 ctatattaaa atcttttttt aatctattta gtacatgcaa taaacaaact gaatcaggcc
     3481 ctccagaaag acctaaaact attttatcgc ctttttgtat taaattatgt ttatttatag
     3541 tacttagtac cttatcaaat atcatattta tccctcttac acttagtttt attcactttt
     3601 aagtatactt tctataaaaa aacgctaaac ccttgtatca attttaagaa attaaagttt
     3661 aatataaata taataatacc aaataaatta aataaaaggt agttttttca ctacctttat
     3721 aaaatttctg gaaaatagct atagttatta tttagtatct atgtatatat ctattttatt
     3781 cctacctaaa aataaatctt gtacatttat attatagtct attttcaatt ttatgtgttc
     3841 cccttcttgt atatttatat ccaattttct tgtatcaatg tcaattaata aagtaccttg
     3901 tggggttaca tactttgtgg tactactctc tccacattta aacagcattg ttgagttaat
     3961 agcaccaaat tttttgatac taacttcatt tttaagtatc tttatagtat tagttatttc
     4021 tatattttct tccttttcct tgtaaacaac atatattcca tcatttttat aaaaaatttt
     4081 accaaaggca gtcatctcta tggtgtccat atttcctttt tcatcatatt gtctagtatt
     4141 tatacttatt tttacactca acgatttttc ctccatagat tcttcatata aactagtatt
     4201 tttgtatttc tactttttga atcctatcaa tttttttctt taagaactct cttgctatat
     4261 ctgtaaattt ttcaggtata tctgatacat aatattgata agttccatga atttctgtat
     4321 tgtttataat atttttcacc tctaaaacct tttttaaatc ctttgcagtc tctttggctg
     4381 gattaacaag ttttatatgc tctccaactt cttcgcctat tgttctcttt aaaataggat
     4441 agtgagtaca tcctaacact aaagaatcta tatttttttc tttcaattct tgtaaatata
     4501 tctttgctgt caatttagct acttctgtat ttgcccatcc ttcttcgaca ataggtacaa
     4561 ataaagggca tgctttatta acaatttcta tactctcatc tattttagat atttccaaat
     4621 tgtatgcttt tgaacttata gttccttctg ttcctattat tcctacaatt ttgttttttg
     4681 tagaacttac agctgttcta gctcctgctt ctataacacc aattatcggt atatcatact
     4741 tttcttgagc ttcttttaaa cttcttgcag tggcagtatt acatgctata actatagctt
     4801 ttacaccttt tgtttttaaa aagtttatag cttgaaaggt atatttaatt atagtttcct
     4861 tagatcttga accatatggt attctagcag tatctccaaa atatattata tcctcatttg
     4921 gtaatatctt cattatctct tttaaaactg ttaatccacc taatcccgaa tcaaaaactc
     4981 ctattggttt attgctcatc tttatacaac acctacttta catttttgtg tttaacaaca
     5041 acttatttat cactaaaata tttatttata ttcataatta atatattatt acctaaatga
     5101 ttattatagt ttattttaca caaaaaataa aggagctatc ttaaattaga aaatattttc
     5161 tagaaaaaga caactccttt cactacttaa aactttaaat ttattttgca aacacatgat
     5221 ttcctattct catataagga ttcaatctat ttatccattt gcaagtggct atttctggat
     5281 tccagaaata tactgcttta ttagttgggt cagttccata aagagcttct tgagctgctt
     5341 tacgtgctga gtctgttggt gccatcttta ttgaaccatc aagcacaact gagaaagcat
     5401 ttttttgata tataacctct tctattgtgt ctggaaatct agggtccaat actctattta
     5461 ttactacagc tgctacagca acctgtccct catagctttc tcctctagct tctcctgcaa
     5521 ccaacttaga taataacatc aagtcattat cagataaatt tattacttct ttctttgcta
     5581 tatttttttc ttgtttgttt attttctcaa tctttgctgt tggttcatat gcaaatacct
     5641 ctttaatagg cataaatata aaagtcaaag ctaatagtgt agccatcagt ttactccacc
     5701 tgtccatgat taaaaccact ccttacattc ttatttttaa aattttttct ctaaatcctt
     5761 cactacttca attactttaa atttaatttt tactctactt gttttttttg gtgtatcttg
     5821 ttttattaac ttatattctt tatcagttag aacttccttc aacttatcat ctgtagattt
     5881 atctattact ccattagatt catcaacaaa gcatagtgga gggaacataa cacaccacca
     5941 attttttcct tcaccttttc caatgataat ctttaatgcc ttatattcac cagctggaag
     6001 aactatatta gaatattgtt tagtaggaaa attgctatat tgtataccta cctttacact
     6061 gtaattatat ccattttcaa gaataatatt tttacttatt tcttccagac tactatattc
     6121 cttttttata atagcttcac tttcttttat actttttgaa ttttgaagct ttggttgtaa
     6181 atattttata acttcatctc taacctttag tttaagttct tggtcttcat ctgtattact
     6241 atttgctata acatgaaatc ttattaattt atctttgtaa tcctttgata tattgtctac
     6301 tttttttacc tcaccattta ttactattgt cattattgat atgactgata taagacttaa
     6361 tattaatagt cccaatctaa tcttaatttt tctcattgaa aattccccct ttaagataaa
     6421 tttatatcat caattatgtc caattaaatt taatttattc ataatatttt ttaatactaa
     6481 taaaaaaagc tatcttaaaa tgattacaat cattttaaaa tagcttttta aaccttatat
     6541 tttataagtc tttactaatc atagccttat ctatcataaa ctgctctgct ttttctatat
     6601 gctctgtagc atacttcttg gatagctcac tatcaccttt aattatagca tcaagtaaat
     6661 atttatgctc ttcaacaata ttatgtgatg tatcataagc agacatatag gtaactctaa
     6721 acctatatac ttgttcccat aatgagttta ttagttggat taatttttta ttattagttg
     6781 ctttaaatat acattcatga aattctacat caagttttaa taacgcatct acatcggatt
     6841 ccaaagtgct ttttttaaat tcttctgata tatctttaag ctttttaata tcttcttcac
     6901 taattctttc agcggcaaga tatgctgcta agccttctag gcttgctctt acttctaata
     6961 catccataat atcctttaat gacatatttg ccacatacgc accttttcta ggcaacataa
     7021 cgactaaacc ttctaattca agctttctta ttgcctctct cactggagtc ctacttactc
     7081 ccaattgttc tgctagttgc acttccatta gcctttgacc aggctttaat tttccttcta
     7141 agattgcttc tcttaaattc tcaaagacta catctcttaa tggcttgtaa ttatccaagt
     7201 ttagtttagt taaattctcc acaaatttca accccttttt gactgctatt aacaacatac
     7261 acctgtttat atttttttaa taattctttt tttccaatta gagcatcttc tttattttta
     7321 aatagtccaa aaactgtagg accacttcca ctcatcatag aacctaaagc attatttttc
     7381 atcattattt gttttatatc acttatttct ttgtgtttac ttatagtaac attttcaaga
     7441 atatttacca tgctttctga tacagctttt atatcttcag attttaaaca ctctatcaaa
     7501 tatttattat ttggtctttt tttaatatta ttcaaatcta atccttgata aacttcttta
     7561 gtagaaacga ataagtctgg tttgcatatc aatatatttg tatcacatgg taaacctttg
     7621 atgcttgtta gcttttctcc aataccttga gctagggcag gtcttcctga tatacaaaaa
     7681 ggaacatctg cgcctaaatt aagtcctatt tcttttaatt catcttcaga taatctaagt
     7741 ttccatagtt gatttaaacc tactaatact gcggctgcat tagaacttcc tccagccatt
     7801 cctgcagcta caggaatatt tttttctatg aatatctcta cacccttttt tatataaaat
     7861 ttatttttaa gtattttggc agctttataa acaatattat cttcatctaa aggaatatct
     7921 aaactagtgc tttttacctt tatttcatct tcttctaatt cttttatctt tactatatcg
     7981 tataaatcta tcgtttgcat tatcatttca acaaaatgat aaccgtcttg cctttttcct
     8041 aagacatcaa tggataaatt tatttttgct ctactcttta gtcttataaa atccattcta
     8101 tcctccttgt ttaaagaata atgcatcact aacaataata ttatactaca aaaaataaaa
     8161 taatagggta ttataatacc ctattatact taattacttt aaatttttta atattaatct
     8221 actaatacga cttttttttc taaaataaga cacttaccag gcttaattgg ttcatcaagt
     8281 tttatatcat taagctctgc aatttcgttt tctgttgtat tgtatttttt tgctatattc
     8341 caaaaagtat ctccttcttt gcatatatat acgattatgc taggagcttt agataaatca
     8401 tacacacctt ggtcttcacc cttgataata aaattttctg ctttcttatc taatgcttca
     8461 gtaaatctct taattttaat aatcaagtct atctggtccc tattcaaatc aacttcaact
     8521 ttatcaatac atgctgtatt aaacacagat gctgtatcag ttagattatc catttctata
     8581 tcatgttcaa aaggaatttc ctcactaatt ttataaacca gttttaaacc ttcaactggt
     8641 acaaataaaa tttcaacttt tatgattcct tgtataatgc ttttatttcc ttcaatataa
     8701 ctattttcta tagacatggt tggacaaacg cttacaatat cttttatttg tatatcatca
     8761 ttatcatttc ttatgccttc tctaaccata aatgtttctt cactacgtct taaagtctta
     8821 tttaattgaa taggtttatg gtcaaatttt attatttttt gaggcgaata tgcatcttgt
     8881 aatacttctc ttgtaacttc atctgtaact tttaccttac aacaagccat acaatctatt
     8941 tctaaaagac ctgtgttact ttcactattt tgcttaaaaa tatgattaaa atctgacata
     9001 gacaacaata cttcttcagt cataccatca ctaaccccag gtacttctac aaattgggta
     9061 aactcaatac ctactctatc taactctaca agttcaccct cgtatgtaca agctaatgga
     9121 tttatttcta atactccacc aataataact ttattgtcag ttactctact ttcttttact
     9181 ttaacacatg gatttaaact tattatagat tgaatttcct ctgtgtttat tgttatagta
     9241 tctcttatag aactttctgc cttttctatt ccaactatat cttgaaaaca aatttccttt
     9301 ctgtgctttt gtatgccttc tacctgtgcc acatctttta caatgtctag cctttgcttt
     9361 tcaaacaaac ttccccttat attcataaga gctcctactt taatttttct ctcattcatt
     9421 atagtacaat ccatatgctc tacttctgaa aataacatgt attccatatc ttgaacaaca
     9481 ttgtcttttt ctattacttc gtttatatct acttttccat ctacattaga aatagtattt
     9541 ttatcatctg caatatagat tacattataa ttaaaacttc ctctgcaaag tatcttccca
     9601 tctgccattt caatcttttt aagtgatatg tatccttctg tttttacaat ttcatataca
     9661 tctaattttt tgtctggtac aactgcctcc gcttcgataa atgtttgaaa ttttccaaag
     9721 tctattctat tgtcaacctt aattacatct ttaattaatt ccatagtcta cctccttaag
     9781 tattataaaa atatcacact atatttatat ttaaggagca aaaaaaaaat tacacctatt
     9841 tttaataggt ataattttaa cttatctgta atttatcttg atctctaaaa acttgcaact
     9901 ttacattaga tgttaataaa tctgagtaac tataagatac cctaggatat ccattacttt
     9961 catcatctaa ttttataaca aacacgcttg gataaacttt ttctagtata ccctcttttg
    10021 taataatctg ctttcttcct ttattagctt tcaacaatat tttctttcct atatgtctct
    10081 ctaagcttac tcttatctta tctagagttt gaacagtagc cacaatatca ccttctttaa
    10141 cgtttatatg tttacataat atcacatata aacatttttg tcaaatgttt aaactaatta
    10201 ttttatatat tttttgcaaa aatgtcaata ctatttttaa agatatacag tataattatg
    10261 ctaatttttg ctaatgtaat attgtttttg gcattgccca tctaaatttt cctcttgttt
    10321 cagaaccacc aatcccctta actcctgtaa tagtctgctc tataacctca tcaataggca
    10381 ctactacatc aattcttgaa caagcaattt tctccactat aaaaacaggg tctaatgcat
    10441 gtatcattat tcttccaggc gaacttgcat agtttgctcc tgcacttatt attttttcat
    10501 aatttgattg gcatgctcct gcaaatatga caagattatc caaatttggt tgccatttgc
    10561 gtgcttcttt tactgtttta acaaaatttg aagagtttct atagttactc atatcttcta
    10621 tatctcctct ttttattgtc attgcatcat gacctgttat tactagtata tccggattat
    10681 atttttctag tagtgctctt acttctttat actgattttg ttctgaaaca gctacaccta
    10741 ctgcaggtat tccaagttga gcatatacat ccaagcaaat ctttaaatat tctttatctc
    10801 catctatctg taataccttt ccaggcattc catatgtgtt aggatttaat tgaagttttg
    10861 gaactgctct tgtcattctt ttttgtcttt ccttagcctt tcttactgac ttatataata
    10921 aattttctac atttttatct attaatatat cttttatatc aggtgctttt actaattcta
    10981 ggtcatcaat ataagcatct gctattactc taaatgcaat tccctttagt atagctattt
    11041 tctcattatt ttcatctaca ccaaaagaga ctattttaaa tactatgtct ttgttatgtg
    11101 actttctagc tacaatgtct cctaccttca tagttaaacc tccaataaat ttttatctta
    11161 gtttatacta tgttcgatat aaaactttgt ttcctaatgt caaaaaaaca tttcttataa
    11221 tacttctttt attactctta aagcattttt atagtatatc ttttctatct catcttcact
    11281 aaacccttct ttttttagag gttcatacaa tttacccatc tgagatatat cttcaatctc
    11341 aacttttgaa tctattccat caaaatctga acctagagat acaacatcta ttcctccaac
    11401 atttacaata tgctttatgt gtctaaccat atcttcaagt ttactttcgc ttttatcact
    11461 taaaaataag tggaagaagt ttatacctgt aactccacct ttatttgcta ataccttaat
    11521 catatcatca gttaaatttc tagaatgatt catcattgct cttgaattag aatgtgtagc
    11581 aattattggt ttagaagaaa tcttcgcaat ttcataaaat ccaccatctg aaatatgaga
    11641 aacatcaact aacattccca attcattcat cttatgtact acttctctac caaaatcagt
    11701 aagccctttt tctctatatt ctaatttatt atgaggaaaa ctcaattcat tcacatgatt
    11761 ccaacttatt gtcatcattc taactcctaa gtcgtaaaat ttatttaagt tttctaattt
    11821 accttcaagc actgcacctt cctcaataga taaaagagct gtaagtttac cttctgattg
    11881 gtttttcata atttcttcat agttagtagc taaagctatt tcatcactat tttttttcat
    11941 ttcctcatga aatttagttg ccatactcat gcaataatca aaaggatgtt ttacttcttc
    12001 agtatcaaca aaaagagcaa atgtttgagc taatgaatcc ccctttttta atctgtctat
    12061 atcaacagaa tatttattag acttaagctc acttgtttct acattttcca ttaattttgc
    12121 tatagtatca caatgtaaat caataaattt catatttata ccccctgtat attttatatt
    12181 tatatctaaa aatagaaata gttgtcctta tagacaacta ttgacaacta ttttttaata
    12241 ttctttttga tattacttaa tcctattctt cttttaagtt aggtattact tttttaactt
    12301 cttcaatttg atgccatgtt ttatctatat tattttcact aatatatttt tttaaatcag
    12361 ttaaagattt aaaatcttta actgataaat tgtcatcatc atctgcaaat cttaaaataa
    12421 acatgagact accttacttt ccacaacatt tcttatattt tttcccactt ccacatgggc
    12481 atgaatcatt tcttcctatt tttgcttctt taactattgt tttagacttc ttataagcct
    12541 ttattatttc ttttctttgg tctgctggta gtatatcttc ccaaccttgt aaattatata
    12601 gccaatgggc ttcaacagtt accatattgt tatataattt ttcccaatct atttttatag
    12661 aaacttcttt atcagcttct acatcttcta aaactatatc ttcttttaaa ctttcactta
    12721 ttccatctat gaatcccatg aaaaattcat tagtagttcc aaatttttcg gctaattcgc
    12781 ttactttacc ttcaacaaca tccattttat tatttaatat ttcattgtat attccagctt
    12841 caactttcaa atattcttcc cagaatttta cttctgcttc ttgattttca tgattatcac
    12901 ttaaatttct ccattcagta tataaactca tactttttcc tcctaagtat acctatattt
    12961 ttatagtttt tatagtataa aatcttttag ttagattgga agtttcttct ttttgattat
    13021 accatattct atttaaagtt aactcttata ttatatcata attaaacaat tcttttaata
    13081 cttttatagc atactcttgg tctataaaat aagggcttgt cgcaattgtt attacttttg
    13141 cttttttaat taaatttttt atcttgtaaa atttgagttc aaatggtata tagtccatat
    13201 cacttgaaaa tatatccaaa tctatatcaa gaacaaactc tgattctaca tctaaaccaa
    13261 atccatatag gctatctatt attattaatt ctgaaaatat gttatatttt aaggcaggtt
    13321 ttataaaact tcccacattt aaaacttcat ttgtatacct aaatacatct tttatgttat
    13381 ttatatctac attatagttt tcaggttctc tagtatcctt atgttggtct acatgcacta
    13441 acttacatcc ttttgtaaac tcacccttta acaaagattt tatccaaaaa taaaatgcat
    13501 ggttatgatt atcaaataca tatatctttt tatttcccag gacatattcg accatattct
    13561 ccaatccttt tgcttttatt tccttatttt catctacttc attaaagact acctcattgc
    13621 ccaatcttac attatttaat gtaccattta taagttttgg aacatatata ctcttatttt
    13681 ctcttttatc atacgaaaat acgttatttc ccaccggttt ttctatataa aatccactat
    13741 attcataatt ttccataaaa ctttacttcc tccattgtta taatatataa tctataattt
    13801 taaaaattaa aatgcactta ttgtaaatca tattatctac tatagaaaac atcttatata
    13861 actaaatata atatcttctc tcaatatgta ttatacaata agtgcaaaat atatctatat
    13921 aaaatatact acattcctat aacaaaacca tcagcttcaa ttggaaggta actaactctt
    13981 ctattcaact ccacttttcc aaaaaatact acccaatatg gtctaaaaat actttcaatt
    14041 ttgactattt caatctctgg gattccaccc ataaacctat gagttagtct catagctatt
    14101 ttatttgcct ttgcttttac tcttcgttca tccttatcac tatattgcac aatattacaa
    14161 tccacatttt ttataatttc atatgtagga aaatcttgta ctatactacc agaacctgta
    14221 gagccattaa ctaaaatttt caattcattc acaccattag aatatctcct actcttgaaa
    14281 atggatttag ttttgtgaat tttaagtgtg acaattttaa actctatata atgaagtcta
    14341 acttcatgag catatttatt ctttaatatt agcttactaa ataaagaatt ttttccactt
    14401 ttagctatat ctatagcttc ttcttttgta atttttgtag gtaatgccct tatatccata
    14461 aaatcattct ctttcttatt tttttcttgt catttttgaa actctatata tataatcaaa
    14521 aaatattata attacaactg ccataactcc atatggaatt attcttccaa ctataatatc
    14581 atttctagtc aatataccat aaaatataaa tcctgttatt aaaaagtaca ataatactag
    14641 aaaaccatct attccaagcc attttatttc taaatctttt ttcaccttag atactaattt
    14701 agacatagca gtttctcctt ttatagatta ttttgtgtat ttaaattttc ccctattcta
    14761 ttgccaatca tccatgcaat aaatgaaaaa ggtatagcta tcacaagagg ttctaactca
    14821 aaactctgaa ctgggaatat tttaaaataa ccaaaagtca ctccacctac aatcattcct
    14881 aaaataccac ccatagatgt ccttcttcca tttccaagaa gtccacctac tataggtaca
    14941 aatgctgaac ccatccaaat acttcctaca aatatacatg catcatatac attttcaaat
    15001 ctaaatgcta cactaagacc cataactgct gctaagcata cacctattct agtaaacttt
    15061 actaattgtt tctgagataa ctcttttttt gtaattcttc catatatatc atttgctaat
    15121 gtagctccag ctgctagata atagctatct aatgttgata ttatagaacc taaaattcct
    15181 attataaata ttactcttat tccttgtggt aatgtatcta gaactaaagt tatgtatcca
    15241 gcggctggag ccatttctgg ataagtagct cttactataa gtcctgtcat agttaacacc
    15301 atgtcaaaac atatccatag tgaaaaacaa gttaataaag ctcttcttcc aaccttagga
    15361 gaatctgctg ctgaaaatct ttgataaaaa gttgggtctg aataagctcc aaaagaatat
    15421 acaattaaca tcaatgcttt catagctgac ataccttttg tagggtgcat aagctgtggt
    15481 gcatctttga gtgcttctgt gagaccttga aatcctccta tttgttcaaa ttggcctggc
    15541 ataaccatag ttaaaccaaa taccatacag aaaaacaata ccatatctgt aatggcaact
    15601 cccataagtc caccaagtac tgtgagtaca acaactattc ctaccattat taagcctatt
    15661 aattctttat ctattctcca tgctacgttg cctatagttc ccatagcagt tatttctcca
    15721 agttgtgcac aatatataaa catcaaaatt gccccaatta tagcaacatg cttgccataa
    15781 aaactttcca gtaaatcagg aactgttata ttggttctta tatgaatcct tggaccaacc
    15841 cacaatgcta aaggcattct cccaatatgt gcagctattg accaaactgc ccatgcagat
    15901 attccatata tagctgcata ctctacacta cctactgtac caactcctcc ataccatgat
    15961 gcaaccaaag ttcctactat caaggaccat ggtaaacttc gatttcctag gtaataactt
    16021 tccatatctt ttacatttct agaaaaataa taacctattc ccaataatat aaatgcaaat
    16081 ataactataa tcccattctc ccaaaatgtt aacatatcta atctccacat tcttatattt
    16141 taatttttaa ctttaatatc taaatatgaa caactctacc catttccata aaaataggta
    16201 gagttatata ataattataa gtatttaaac aatcttgtta ttaagcaatt ttattgttca
    16261 agctcttatt ttctctttta tttatcttat ttaaagcata agtagcaaat atacctataa
    16321 ctgcacatac tacagataaa ataaatatat atgtatatcc tgtttgtcca tatttatcta
    16381 accaattacc tgcaatagtg taataaaatg catctggaga aaaccctata aatgaagcaa
    16441 atccaactac tgctcctgta gtttctaaag atatattaga ctctgaaaca gatgcaaagt
    16501 atatacctct aaatccaaat aaaattacac ttagtattat catgtttatt acagctatcc
    16561 atataaatcc tgtactctta ggaataacca agtaagcagc tgtacttact gtcattagta
    16621 taaatcctac aaacattact cttatagatg acccaacttt atctgttatt acaccagcaa
    16681 ctggagatgc tcccattttt ataacataag ttctaattat tgatagagca gaaactagag
    16741 tcattggcat tacataaact tctgataggt atggacttaa ataagttaaa cttgagaata
    16801 ctaaataagt tgaaaatatt ataagaccaa ttagccaagc ctttggcatt gtaactacct
    16861 ttagcaatga cttaatgctt aatccttcat ctgatgctcc actatctttt ttctcttcta
    16921 ctaagaaaaa tagaagtaaa ccacatatta tagatgctgc agaatataac catactacat
    16981 atttgaatcc tactgttatt tcagcaaatt taccaaagaa ataaagacct ataaaagaaa
    17041 ttaatgtacc tgatacacct gataatcctt cataaaaacc aaatattctt ccttgctctg
    17101 actcacttcc ttgcattcta acaaccttaa cagatgctga gaaaaaagtt aatatggttg
    17161 taaatcccca taatacaaat attaaaagta tcatactata tgatgggaat gtagaaaaat
    17221 aaaacccaag cgctcctgaa gcaattaaag aaaaagttat cagctttcta actgagaatc
    17281 tatctgcaaa ccatcctcct ataaaataag ataccattcc tactaatcca tataaactta
    17341 ataagttccc tatttgtgta tgactcaacg ataaagcttg ttgcattggg tcataaaatg
    17401 atgatttcat atatggtaaa ctatacatag ctgttgttcc aaatgccaat atgaatatta
    17461 tcaaaaatct tttaacatta cttttgtttt ccattgatac tctctcctta aaattgtatt
    17521 gtttataatc tcattcatgt aattttattt taatttttct attgcttgtt taaagtcatt
    17581 tattatatca tttgaagatt ccaaccctac agctattctt attagatttt ctccattcat
    17641 ttgaaccaat gtatgctctt cccctaagct tgttgctatt gtcgcaagct ctaaagagtt
    17701 cattaatctt ctactagctt ggtctcttgt taatccattg ataccatcct taagcttaaa
    17761 tgaaactaca cctccaccta aaccattcat ttgagtttta caaagctcgt attgaggatg
    17821 agattttaat gctggatatt ttactaattc caccttctct tcttcctcta aaaactctgc
    17881 tactgctaat ccattttcac aatgcttttt catcctcata tctaacgttt tcatacctct
    17941 taaaatcatc catgcactca ttggtggtaa agacgctcct gtaaaacaac ataaacttgg
    18001 ccatctaact aaatctatta attcttttga acctgctact gctcccccta aagtatcccc
    18061 atgtccattt ataaatttag taagactatg tattactaaa tctgctccta aatctattgg
    18121 tctttgcaca attggtgtac caaaagtact atcaactatg gctaagcttt tattttcatg
    18181 agcaatttct gctattgttt ttatatctac taaatctaat gatggattta aaggactttc
    18241 tatataaact atcttagtat ttggtttcat tgcatctttt acattttgtg gatttactgc
    18301 atctacaaat gtaacttcaa ctccaaattt agataacaac tcagacataa ataatttagt
    18361 gtgtgagaat attccatctg aactaactat atggtcacca ctttttacta atgctaatat
    18421 agtagatgtt attgccccca tacctgacgt actagatata gcactttctg cattttcaag
    18481 catagccaac ttagcttcta actccgtaag agtaggatta cactctcttg tatacacata
    18541 tccccatgtc atacacaact cttcaaaatg ctctactgtc tttgcagcaa atgttgctgt
    18601 ttgacatatt ggtgtagcca atgcacctgt tgttgggtct gcactatgtc cccaatgtat
    18661 tatttttgtc tctaaatctt gattaatatt gttactcatt ttgatttcct cccattttga
    18721 cttatttata caacgttttc cctaccaaat ttcatcaatt tagtttagtc ttaatacatt
    18781 ttttcaagta tacttttata tttgttataa tttctaaaaa tatgacactt attttgtctt
    18841 tttacagttc taattataaa ctctatagta actatagagt caatatgttt ttgatatttt
    18901 ttttacaatg tttaaaatag ttggtacaaa aataggtata tcttagaata attaaagtca
    18961 tcctaagata tacctatttt cataccataa tttaaacaat tatataaagc attaattttt
    19021 ttaccataaa taagtttttc aagagttatc atcttttaat aaatatattt tagttaaata
    19081 ttttaatatt atttaatctc tccaacaaaa tacactctaa aaacaaaatt atataattaa
    19141 aaaaatatcc tataaaaagc taaaaagttt ttctatttac tacaactaaa aataagattt
    19201 gttagaggta taaatgtatt tagtttattt acacctctag tattttacaa attatacctc
    19261 tactgaattg attttttagc acgaataagt gtgctctttg agataccagt catcttcaca
    19321 acttctctat atggtttaga atttaataat cctaatgcat attgtatctg ttgattgctg
    19381 tatttctttg gcctaccatc tttaaagtcc tttttcttcc tagcaaattc ttttcctaat
    19441 tgagtacgtt ctattatcat atttctctca agttctgcaa ctgcaagtaa cgtagtcaaa
    19501 aagaacttac ccattgaagt attttctaag agacctatgt ttaaaatatg cacacttact
    19561 tctttagcaa ataaaccttc tattagttgt atcccttctg atgtacttct agctaatcta
    19621 tccaacttag ttgcaacaag taagtctccc ttttttagag atgatataat tttttcaaat
    19681 ttaggcctat ttgtagtagt gcctgtataa gtttccttta ttattttagc atcattatat
    19741 ttattcaaaa tttcttgctg ttgctgatac aaactgttgt tgtctgtttg attttttgta
    19801 cttacacggc aatatccata tataataatc atcacttcct aacataaaaa ttttgtacag
    19861 aagttaccca gaagcttgtt tttgcttatc tttatccatt ttactaaaac ggttttttag
    19921 tgtcaatact gttaactttt gacaccataa taattccttt ataatttgtt tgactatgtc
    19981 aaaaattacc aatataatga aattaatgag tttatacaaa ttggaggaaa taatatgaat
    20041 agtctgttaa aagaagcgat agatgaatta aaaaacatcc attgcggaga agttttttta
    20101 ttaaaagaat tgttcaaagg ctatgaatgg aacaggttgg agatgaacat aaggttgaaa
    20161 ttaggaaaac tttttttgta tgaagtggta actaatccca atttaaatgt agaggtcatc
    20221 aataaaaact ctgcttatca gcaaatgtat aaaaaaaaat agtgacttaa atttatataa
    20281 tagtataatc ttcttattga ttcaaaagtt aaaactttta atacaaaaca atcattctat
    20341 tttagtattt atcaatatgt ctaaatttat ataattaaca cataaaaata gtacttgttt
    20401 aaatcacatt ctttaagata gataaatctt aaccctactc cagcataaat actaaaatag
    20461 ggcttagaat tatctatatt tttatcccat aaaatactta actcttcctc ttgattgaac
    20521 atatatatct ggggaaatac aataaaaacg tgaatttata aaatttccaa agtcagaaaa
    20581 cttcaactta aacttaggta taccaaaact ttcaggtgct atttcatcaa ccccaaaata
    20641 aattacaatt ccactatctg taagataaaa agcttggtct tcaggtataa ctaattcaac
    20701 attagaataa tacatttctc tattttcatt tatttgagat ttaatgtagt cagtaattat
    20761 attaatataa tcaactccat ctctaaaaat atcgttaagt aaaagttctt ttccagttgt
    20821 caaatctata ttgtaattat tcaatgtatt gtatttaggc ccaaagttat tggcaaatcc
    20881 cataaggctt aatatcatac tcagtacata atttttatta aaagtaactg cataacttgt
    20941 agatacccag taactttgtt ttggaagtga attttgagaa gctgcgttat tatattcttg
    21001 ttcttcttcc tgcaagccat ttttaaaatt atttacagtc attcttacag cattgtttat
    21061 gttatttaaa ataactgggt ttacatacgt agattgattt ctaatattgt atataacagg
    21121 atactttaca tcatatgaaa aatacttact tctttcaaaa tcttcattaa attgtacata
    21181 taatatatta tatgtacagg tatttgtaga ttgataattt tccattaaaa tcctcccctt
    21241 ttataaaaaa atcagataca atataatatg cttaaaacag taataatgtt aatagtaaat
    21301 gtaaagaata gaaagtatct aaaacagcaa aaaatgacta attttgtggt ataatacata
    21361 ggattgagag ttattttata ggaggaaaaa tatgttatta ttagcagata aatggaaaga
    21421 ttatgaactt atagatatgg gaaatggaga aaaattagaa cgttggggca attatgtact
    21481 tagaagacca gacccacagg ttgtatggcc aatggaatct gaatgggctt tatggaaaaa
    21541 ccctcatggg cactatcaca gaagcaataa aggtggaggt caatgggaac acaaaaaaag
    21601 atatccagaa caatggacta taaattataa aaacttaaag tttcacatta aaccaactgg
    21661 atttaaacat actggattat tcccagagca ggcagctaac tgggattgga tgatagaaaa
    21721 aataaagaaa gctaacagac ctataaaagt gttgaatctt tttgcttata caggtggagc
    21781 tactgtagca tgtgcatctg ctggtgcaga agtatgtcat gttgatgcgg caaagggtat
    21841 ggttaattgg gcaaaagaaa acatagaatt atcaggtctt aaaaatcaaa cagtaagatt
    21901 tatagtggat gatgttgtaa agtttgttga aagagaaata agaagaggta aaaaatatga
    21961 tgcaataata atggaccctc cttcttatgg aagaggtcct aagggagaag tgtggcaaat
    22021 agaagaaaag ttatatagtt ttgtagattt atgtatggga gttttatcag ataacccttt
    22081 atttttcttg attaattctt atacaacagg attttctcca atagttcttg aaaatgtatt
    22141 gtctacaaca ataggtaaaa agacaaatac aggatatata tatggtgggg aattaggaat
    22201 accagcttcc agagatggta agatacttcc ttgtggtata tttggaagat gggagaaaaa
    22261 ataatgataa aggtcatata tgaagataac catttattag ttgtagaaaa accagttaac
    22321 atattatctc aaggagataa tactaatgat aaagatatgg taaatctttt aaaagactat
    22381 ataaaaaaaa agtataacaa acctggaaat gtgtatattg gtttaataca taggttagat
    22441 agaccagtgg gtggagttat ggtttttgcg aaaacatcaa aggcagcatc tagattgtct
    22501 gagcaggtaa gaagtaagac tttcaaaaaa acttatctag ctgttgttca tggcaagata
    22561 aaatctaact cagatatact aaaggatttt ttatataaaa ataaaaaaac taatatggta
    22621 actgtagtga aaaaaaacca taaggatgcc aaagaagctg aacttaacta taatgtctta
    22681 aactttaaag aaaatttaag cttagttcaa gttaatttaa agactggtcg ctctcatcag
    22741 ataagagttc aatttgcaag cagaaaacat ccattgtatg gagaccaaag atacggcaag
    22801 gaaataaata agattggaca gcaaatatct ctttggtcca ataagataga aatctatcat
    22861 cctactacaa aagaaaaaat ggaatttaca tgtcatcccc ctgacaaata tccatggaat
    22921 atattttaag tctcaaatga ggtgattata tgagcaaaaa attttcaata ggagaaatgt
    22981 ccaagcttca taaaataagc atacagacac taagatacta tgaccaaata ggtttattta
    23041 aacctgttca tgttgaccaa gaaagcaatt atagatatta ctcaattgac caattttcac
    23101 aattagatat tataaaatat ttaaaatatt taggtatgcc tttaaaagaa attaaatcaa
    23161 agcttgatga aaataatgaa gaaattttaa agctactaac aaataaaatt aatatagtgg
    23221 atgaaaaaat taaagaatta gaacttataa aaaaagtact aagcgcaaag aaagagacca
    23281 tggaaaaagg tatgaaagta gatgaagttg gtaaaatagt gagaaaacat attccacgaa
    23341 gaagtatctt atctatagag tatgaagaag gattaagtag tgaagaaact atggaacttt
    23401 caagaagaca aatagcaaat atattagaag ataatatatc tgtattctat ggtggcgtaa
    23461 gtggacttgt atctatagat aaatttttaa aggaagataa agttatttat gacaatagtt
    23521 ttgttactgt tgaaagagat ttatttgata taaaatcaca aaaatatata acggaaattt
    23581 cagctggtga ttttatttgt atgacatata aaggacctta caaagaaaat tataccgctt
    23641 ttaagaagct agttgattat gttgaatata aaagaatacc tattgaaaat tatatatatg
    23701 aaatacctat aatagaccct ctgtctacaa acaatgaaga agaacttcta acagaaattc
    23761 aaatacaagt taaaaagaga gaaattgact taagatgtct agtgtagtaa cctagtttac
    23821 ttacaaatct taatataatt gtctattatc aacatacgat ttttttagat aatgattcct
    23881 aacagtgaga ttttcaaaaa ataggcggga gcatggctaa tgtcaattcc cacctatttt
    23941 taattaagcc atgtcatcac gaagtgcatc aataatattt tcttttttta tcttattaat
    24001 agtatacaac attgtaataa atacgataaa tagaacacta aatatactta ttccaatact
    24061 aacccatgga atcacaaaat cgatatcatc tgtaaccatt actttatgaa ttagccatga
    24121 agaaattact gctataggaa gaccaaagaa caacgccctc ataccataaa aagcacactc
    24181 aaaattcatc atcttttgga aatcatgctc agacattcct acagagcgaa gcatggcaag
    24241 ttctctacga cgtaacttaa tattagttga aattgtatta aacacatttg caatcgaaat
    24301 cagagaaatc ataattatga aagtatacgc aaaaacattg gcaataaaaa tgtaattacg
    24361 gttctcatcc atcattccat acatattgta cagattgtac tcattcgtaa ctccctcact
    24421 ctcaataatt tgctccattt ctgaaactga ctgagttgga ttttttgatt gaaagcttaa
    24481 actttcaatt cctgtagaaa caccaggaat ctcaaactta tctttagctg aataaggagc
    24541 caatactctg aagcttgctt tcttcatatc tgagtttctg attcctggag gagaatcagg
    24601 tggcaccact ttgacaaatg aaatatttac attttgtctc tcaggcgtgt ccaacttgcc
    24661 attaacttca ggagtgaggc taacatccat agaagaattg gtaaaaatat caataatatg
    24721 attatctttc gttaacatag aaacggcaat catttttgca ttttgcccag tatattcttc
    24781 tgttggcaat ccaagacttt tgataatatt cagataagtt ctatcatcaa gaaactgcat
    24841 atctactggc aattcaagca tttcactcat agaatgtaaa ccattatagt tcaaataatc
    24901 gtcagtaagc tcacttactt tggcaacaca tgaataggtc atcagtttct gatacaaacc
    24961 ttcgtaaaca ccacttgcag tttttagctt atcataaagc ttcaacattt cgctgtcttt
    25021 catgccttgt gtagaaaaaa taatgtcttg gtcagtaacc tctgacctct gatttgacat
    25081 ctgttttagg tcttttacta aagcacttgt agagatgaat agaactatgc ttaaaacaag
    25141 cgacaataca atacttcgat aacgtttctt gtttctttta aagtttttca tagcaagaac
    25201 tccctcaaga ccataaattt gctgtgttag ctttgatgtc ttcacagatt tagattcaat
    25261 ttttacctca tttgtctgac gaatacactc catcactggt gtgttggcag cctttcttgc
    25321 tggtatgtaa gcagaaatta agattgtaac catgcttacc actgctgcaa cgacgattgc
    25381 aggtatagat aatgtcagtg ttaatggaac attgacgtag agaatatttg caaagttttt
    25441 agctattaca gaaatcacaa gtccaatact gactataccg attacaacac caattggtat
    25501 accaatcaca ccaatacaaa ttccctcaaa taacactgaa tttcgtaact gttttgctgt
    25561 agctccaaca gatgaaagta ttccaaattg atgtgttcgc tcgttcaatg acatattaaa
    25621 tgaattatat attagaaaaa ttgagcctag cataattatg gcaagcacaa cgccaccaac
    25681 cgagtataaa aacatattga acaaattatt atcagaaata cccatgaaac gcaacacatt
    25741 atcattgaaa atataatcat gctctctagc actacttgta taagagcgaa catgacgtgg
    25801 atttttcaat gtgacaaaaa ggctaagact gtcagccttt acttgttcat cttctttggt
    25861 tatcaaggta tatcctggtg cagaagattc ttcaaataca ggctttctac agatacccac
    25921 aactgtataa gttctcttat tttgtggaat aaaagcttca ctcccagcag tgtatgggtc
    25981 actctgacca agattttcat tttcactcat tcgtttccct acatccaaag aaatagtatc
    26041 acctactgca aatttgacac caccatctgt cgcaactttt cctgaaacaa gaatctctct
    26101 actattttca ggtaatcttc cagaaattaa agttataggc aaagtatcaa aagcttcttt
    26161 gctgaatcca gcaataaaaa gatatggttt atctggattt ctgctaccct caagtgttgc
    26221 atatccaata ttttcaaatg ttacagtatt ttcaacttca tcattgaccc tctgttcctg
    26281 tacaaaagaa gaatcaacat ccaaaaactc gacatgccaa tcaccatatt ttataatggc
    26341 accatttatc atatagttca tcaaagaaac tccaaaggta gtgactgctg taatcatagc
    26401 agctgacaaa acaactccta taattgttac aaaagttcga gtgcgattct ttttcaaccc
    26461 ttgcagagca actttgttaa aaatattcat taacggttca ccttcctctc atcacgcact
    26521 acttttccat ctgaaataca gataattcta tccgcctgta aagcaatgtt ttcatcatgt
    26581 gtgacaatga tgagagtttg gtgatattta ctatggcttt ctttaagtaa ctggataatt
    26641 tcttgtccat ttttgctgtc taaactacct gtaggctcat cagcaagcat aactgctggt
    26701 gcattcatca atgcacgacc aatagcaaca cgttgctgtt gacccccaga aagctgattt
    26761 ggtaaatgtg tttttcgttc ttttaaacca agtaactcta gcaaatcatt taacctttct
    26821 tggttaacct tacgcttatc cataagtata ggtaaggtga tattttccac tacatttagt
    26881 gttggtataa gattgtgaaa ctgataaatc aatccaactt gtcgcctacg aaaaatagca
    26941 agtttttcat tgctctgacc atatacatct tgaccctcca gatatatctt tccacttgtt
    27001 ggtacatcta ctcctgcaat agaatgtagt agtgtagatt taccagaacc agaagaacca
    27061 ataattgcag taaactctcc tttttcaata gtaagtgaga catggtcaag tgcagtaacc
    27121 tgattttcat tcttaccata aaccttacat aagttttcaa tctttaaaaa tgccattata
    27181 taagtctcct ttcatatttc ataaatatat catagaactt tcaacttaca tttaagtgac
    27241 atttaaatga gagattcgtc actttggaaa acgaataaca aatattgcac caccttgtgg
    27301 gtgattttct gcagtaattg ttcctccttg cctcataata atcgtcttac aaagtgccaa
    27361 tcctattcca taaccagctg tgcttgaatt tttcccacga taaaatctgt taaacagaca
    27421 tggtaaatct tcttttttaa agccttctcc attgtcatga atagtaagtt gagtaaacaa
    27481 aaagttgtcc tcacaaacaa tatcaatttt cccattatcc cccacactct ccatgcagtt
    27541 tttaaatata ttttgaattg cttctgaaag ccaatttaaa tcgcccaaaa tctttactcc
    27601 ttttggtata ttaatatgta gagtgatatt gtgtagttcc ataggaatca aaagttgatg
    27661 aagtgcagaa ctaatcaaat tatccacatc aatttcttct ttttgaaaaa ctacaatacc
    27721 tgcatctaaa cgtgataatt ttaaaagtga agtaatcagc cagtccattt gtataagcaa
    27781 ttcttctgtt tctcgtatca actcttttct ctcatcttca tcagaagtat tctctaacag
    27841 tgacaaaata agagttactg atgtaagagg agtgcgaagc tggtgggcta tatcggctaa
    27901 tgaatcagca agatgttctt tttctttttt cagtgcataa ttttgttctc taatacgtaa
    27961 cgtcatttta gttatttcac tttgcaaaat agaaagctca ccctcatctg attcagtaat
    28021 atacagatgg ttagcattat gaagcacaag attaatttgt tctgaaatct gtgcaatact
    28081 tttgtatcga tttttagtaa acacaaaaaa tgctgttcca aaggtagtgg cagaaacaat
    28141 agaaattatt ccagtcatag tactgattgc aaatcccagg gctacagtga gaatagtaat
    28201 taataaaaat aaaatagcaa atcttcgaaa ctctctattt cgaaacataa cttcctccca
    28261 atctataccc tgtcccacga acagtcaaaa ttatttgcgg acttgaaggg tcatcttcta
    28321 tcttctctcg caagcgtttg atgtagacag tcaatgtatt gtcattaaca aactcacctg
    28381 ctgcatccca caattcatca agtaatctca ctcttgtaat aatactttta ggattgctaa
    28441 taaacaccaa taacaaacgg tattctaaag ctgaaagaaa aacctcattg ccattctttt
    28501 tcacaacacc ggttgccgta tctacataaa gcccacaaat ttcaaaagtt gacccaaaac
    28561 gcccactttt tcgtagtgct gttctaattc gcgcaatcag ttcacgtgga cgaaaaggtt
    28621 tagtgatata gtcatctgca cccatattca gcccagtaac aacacttgat tcatcaccag
    28681 aagctgtaag aaagataaca ggaatatctt gattttcttt gatttctgta caaatcgtaa
    28741 acccatttcc atcaggtaaa gaaatatcaa taagtgccaa atcaaattta ttcttagcaa
    28801 tctctacaag tgcttcactt cttgtggata catgggttac tataaatcct tctgaattaa
    28861 gcaaaagaat aagatttttg gcaattgctt tatcatcctc aactaaaaat atccgtttca
    28921 tttactttca tcctccttta ttttattagt tttatatatt ccagcagagt aataatacac
    28981 tactatttta cttattatta cacaattttc attagtttct tttgttctta tacaatctat
    29041 gcataatacc tccattgatt tattatattt cttataacag aaatacacaa gataggataa
    29101 aaaacataat gtaagtgcaa ctatttttta attcactaat tcactaactt ataaacacac
    29161 attccaatgc acgccacctc cctgatgatg tacttatcaa tctacatgtt tactatggta
    29221 ctcccatgtt agtatacact ttataatcaa tacttgaaaa actaagctca atgttttatt
    29281 atatacttat atatacctta tattataagg tatatgataa aataaagtag gtgaatctat
    29341 ggacttgaat aaagaagtac ttaaaggtca tattgatact ttaatattat caatactaaa
    29401 taaaggggat tcatatggtt atgaaatagc aaaaatagtt ataaatgaaa caacctttga
    29461 attaaaggaa agtactctct atgtatctct taaaagacta gaatctaagg gtctaataaa
    29521 atcatattgg ggaagtgacc aaggacttgg aagtagaaga aagtattaca atataacaga
    29581 tgaaggaaaa gaaaatttag aattaaagat tcaagagtgg aactttatac aaagcgttat
    29641 gaacaaattt ctaaagagag gggaatagat ttatgaaaat aatagaagag tatttagaag
    29701 cactatataa aaatgatact agcaaagaaa ttcaagattt aaaagaagaa ttaaaagagc
    29761 atctaataga ttccactaat gaatttattg agaatggata tgacataaat gaagcacaaa
    29821 ataaggcaat agaaagattt gatggcagta atggagtatc agtagaatta cgttcaatct
    29881 ttaaacaaaa aatagaacct aaaaaagtac tattacgaaa attatcaaat tcaagaattg
    29941 tatttttaaa tttatttgga tggcttcttg cagctactgc atatacaata aatagaggtt
    30001 ttggtcatat agctccacca tggataatta tacttttaat aatatcaata gttatattaa
    30061 taatcttaac tattataatt aagggattaa aaaaggaaat agaaaatgat tacaatatat
    30121 agttatacag ttatattgta atatattatt tattcttata aacacatatt ttgaaaggag
    30181 ctttttatat ggtcaaaaaa attctattag aaaaatttct tgatacctca ggagtttcat
    30241 atatcaatga aaaattgaat ctatttaagg atactaaatg gatttcattt ggcacctata
    30301 taatgaccgt tgatagtttt tgttatagag aggattcaaa gcactataat ccaataatgt
    30361 ctacctttga ttatgaatca gagattttta tagttaatgc cttatacaag gaaaatatct
    30421 attctattaa aagtaaaaaa ctctatagga atgtatctaa aggagataag ataattgtta
    30481 caattaaata ctcttatgat aaatatgaaa atcttataca tgaagaaatt catgactatc
    30541 atctctatcc tctttctctt gattaaaata aaaggctata gcctctatag ctaacgcctt
    30601 taatttaaac tactttgaat actatataat tttcataaaa gactgtaaat aaatttgtgc
    30661 aaaatatata aaatttatct acagtctttt gttatacaaa atttataatc tcttatagaa
    30721 caaatttgcc atttctcaac tttatcactt ttactcagct atattataaa cttttaattt
    30781 atctttattt aaatgtttct tcttaacttc tactaaggct tttagtgtat ccaaagatgt
    30841 cattatttca gtagaaaatt caatagctgt tcttctcatt ttaaatccat ctcttgtaga
    30901 atcatttcct ttagttggtg tatttattac tatatcaact tgtttatttc ttatagcatc
    30961 taatatattt ggtctaggct cttcaattct atttactata tcagcctcta ttccattttc
    31021 tcttaagctc ttagctgttc cttctgtagc aacaaaagta tatcctaatt ctttcatatc
    31081 ttttgctatt tctataaact catctttgtc atgattgttt acagtagcaa gtactac
//
LOCUS       DAMKOJ010000046        30270 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000046 DAMKOJ010000000
VERSION     DAMKOJ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.048"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            164..1261
                     /gene="ychF"
                     /locus_tag="PC592_002203"
     CDS             164..1261
                     /gene="ychF"
                     /locus_tag="PC592_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDF4056173.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQIFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            complement(1871..4150)
                     /locus_tag="PC592_002204"
     CDS             complement(1871..4150)
                     /locus_tag="PC592_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4056174.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEEYFEVDNILSILKKQAINSSFKRM
                     GVILPNGTAYTTDGYREDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSDINVYSV
                     PIYKNNDVKGVIFATHSTKLYEKILSVPTFNGKGYSYVARSNGDIVLNPSSKNANSTK
                     ENLFSYIGKSDSISKSSINNMKSNIKNFKSGSLSYSMSGRGYYLSYAPIGINDWYLFS
                     EVPKAAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRASIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTAVKRKYLKVYEIYAENLKEILIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGIFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPDFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRLIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSVKGKEIN"
     gene            complement(4419..5873)
                     /locus_tag="PC592_002205"
     CDS             complement(4419..5873)
                     /locus_tag="PC592_002205"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDF4056175.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTNADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAISEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            6037..6906
                     /locus_tag="PC592_002206"
     CDS             6037..6906
                     /locus_tag="PC592_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056176.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKNIQFEYHNHDFNKIIIFINGNVT
                     YFVEGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDATSDLEK
                     CFKISTENKCNRLRLNMHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENIESTEDVFYDETIKKVLDYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NSKNPLDITLLDE"
     gene            complement(7120..9192)
                     /locus_tag="PC592_002207"
     CDS             complement(7120..9192)
                     /locus_tag="PC592_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF4056177.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMIDNSMYASIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAVMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDDSETNVEVIDMSKNELASEILVALGNKENLKSLDACITR
                     LRLIVNDINKVDKEKLKSLGAAGVMVIGNNVQVIFGPKSDSIKSDIKDIIEGKTKIES
                     AVIKNNDKNKMKKNMEVANMENALVENIYSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSNDGLIYSPVDGTIGVIFPTKHAIIIKSKKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGITTAKEENRVIIL
                     RDDIEKIG"
     gene            complement(9494..10336)
                     /locus_tag="PC592_002208"
     CDS             complement(9494..10336)
                     /locus_tag="PC592_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4056178.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKNK
                     IERTFIIQDESFLDKIGKLASQVDEKFFAISTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENIIIKNELLHEIKRIHKKEYEIGKWAVDYINKEFGVKFPLDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     REKINDTSNEIIDIIKVKYEKDYNCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(10596..12638)
                     /locus_tag="PC592_002209"
     CDS             complement(10596..12638)
                     /locus_tag="PC592_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDF4056179.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWNNIPLAIYQIVLGIILSILP
                     FKFLFSFNPEIFVICIIAPLLFSEAQNVSRKELLELRKPILLLAFGLVLTTVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFIITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFIYFVAEEVGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNEDMTLKLTFISALIVFILFVIRFIWVYLWH
                     DSFIKTKKNPLNNFFVGFLGFKDEEAVKENISRCKYSLIVATCGVHGTFTLATALSIP
                     FHLANKDVFPMRDTVLFISSEVILISLILATVLLPRLLKSNSQESEHLLSDKEAYKLI
                     LKEAILKLSNEKAQEAQLVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADKQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIIKLKISMWTIDRKVKKEVKEKIT
                     KIVSENKEIIKEFHYAYALSTKTAISFINKNTDENNRHEALISIRFYNRYLNWITRKI
                     QNDDKFESRVEYYRVMAIQSQRDSVQQLVENKQISREVAKELLENILYDEMMMIES"
     gene            complement(12789..13760)
                     /locus_tag="PC592_002210"
     CDS             complement(12789..13760)
                     /locus_tag="PC592_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDF4056180.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFGKEIKFVKAVDGISFDLKKG
                     ETLAIVGESGCGKSSAGRTILRLIEKTEGKVEFNGIDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHDLVPKNEIKDNILNIVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKEELYLHSQHPYTKALMSAVPVQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEVPVLKEISRNHFVACHLI"
     gene            complement(13761..14738)
                     /locus_tag="PC592_002211"
     CDS             complement(13761..14738)
                     /locus_tag="PC592_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056181.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNGVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFQGKDILKMNENELMRIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMLHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVVVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPVLGKNKDKRLYSIPGQV
                     PNPIGIPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            14957..16516
                     /locus_tag="PC592_002212"
     CDS             14957..16516
                     /locus_tag="PC592_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4056182.1"
                     /translation="MKFKKLASLILVSALMLTFTACASNDKEKSNGGKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNED
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQNTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAKIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIEDAKPSPAI
                     LFEDWSKLYVE"
     gene            16622..17581
                     /locus_tag="PC592_002213"
     CDS             16622..17581
                     /locus_tag="PC592_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056183.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     AQDIENIRVNMGLDKPVYVRYLSWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKISSIFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVVTAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            17584..18396
                     /locus_tag="PC592_002214"
     CDS             17584..18396
                     /locus_tag="PC592_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056184.1"
                     /translation="MFTNILKELKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKISTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQKYIFDKLYLAVFPGLLIFLTVMSFTIISKKFSSNT"
     gene            complement(18611..19513)
                     /locus_tag="PC592_002215"
     CDS             complement(18611..19513)
                     /locus_tag="PC592_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4056185.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKIRIGIPPL
                     ILGIVFSDVVAQLVANNPDIEFDIVERGAYDLSRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNYPITWKVVLCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            19866..21044
                     /locus_tag="PC592_002216"
     CDS             19866..21044
                     /locus_tag="PC592_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF4056186.1"
                     /translation="MKDVVIVSAVRTPIGNFGGVFKNTSAVQLGTITVKESISRIGLN
                     LSEINEVIIGNVLQAGLGQNVARQIAINAGIPNSVPSYTINKLCGSGLKSVQLAAQSI
                     ASGENDVVIAGGTENMSQAPYIVPTARFGNKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAEKAIKNKRFKEEIIPVNILIRRGKMETIDTDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSKQKADELGIKPLVKI
                     KSYASAGVEPEIMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVKTGLATLCIGGGQGISMVVSR
                     "
     gene            21053..21709
                     /locus_tag="PC592_002217"
     CDS             21053..21709
                     /locus_tag="PC592_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HDF4056187.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKTTIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            21709..22374
                     /locus_tag="PC592_002218"
     CDS             21709..22374
                     /locus_tag="PC592_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HDF4056188.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDDVNV
                     ILQSENGFLGLGAAEDGNSNDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISSTEAPLILSDSLNGNI
                     SVV"
     gene            22479..23255
                     /locus_tag="PC592_002219"
     CDS             22479..23255
                     /locus_tag="PC592_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF4056189.1"
                     /translation="MLKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNKT
                     TTELQQEGYDCMNVKCDVTKEEEINQAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            23317..24651
                     /locus_tag="PC592_002220"
     CDS             23317..24651
                     /locus_tag="PC592_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF4056190.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVLLNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSVAGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLARELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            25152..26105
                     /locus_tag="PC592_002221"
     CDS             25152..26105
                     /locus_tag="PC592_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HDF4056191.1"
                     /translation="MRKNIPTKLKTILALGVLTLTTASSAVNASALSLENNVNTSNKN
                     LVYSNTRYKFSAKPNCSIKPELKPDKDNSCKDKNHSDKNCNNTNKPDNNKPESNKPDD
                     NNNSGSTDKPDNNKPESNKPDDNNNSGSTDKPDNNKPESNKPDDNNNSDSTDKPDNNK
                     PESNKPNDNNNSDSTDKPNDNNNSGSTSENFSAYQKEVVDLVNIERSKAGLNPLTLDS
                     SISNVATKKSQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVV
                     NAWMNSEGHRKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(26509..30048)
                     /gene="nifJ"
                     /locus_tag="PC592_002222"
     CDS             complement(26509..30048)
                     /gene="nifJ"
                     /locus_tag="PC592_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDF4056192.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLVAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     SIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGVTMSHLRFGDSPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT        10469 a         4754 c         4039 g        11008 t
ORIGIN      
        1 attatttaaa tcaatatgat ttaaagtcta gtttacaagc ttgatatata tgatgtataa
       61 tcaatatgta tgtctataat taaaacaatt ttacaatcct atagattgat tgtttaaagt
      121 tatataaaga atataaaaaa gaataagaga gaggacgatt aatatgaaat taggtatagt
      181 tggtttacca aatgtaggta aaagcacact atttaacgca ataactcaag caggtgcaga
      241 atctgcaaat tacccttttt gtacaataga cccaaatgta ggagttgtat ctgttccaga
      301 tgaaagattg aacaaactac aagaattata taattctgaa aaaatagttc ctactgctat
      361 agaattttgt gatatagcag gtttagttag aggtgcttct aaaggagaag gtctaggaaa
      421 taaattctta tcacatataa gagaagttga tgcaatagtt catgttgtta gatgttttga
      481 ggatgaaaat gtcgtacatg tagatggttc tgtagaccca cttcgcgata tagaaactat
      541 aaacttagaa ttaattttct cggatataga gattcttgaa agaagaatta ataaaactca
      601 aaaagctgcc aaagctgata aaactttagg ttctgaactt gatttattaa aatcaataat
      661 gtctacttta gaagaaagta agtgtgtaag aactatggaa tttacagaag atgaacaaat
      721 attcgtaaat tcattggatt tacttacatc taagcctgta atatatgctt caaatgtatc
      781 agaagatgat ttagctgata atggagaaaa taataaatat gttcaacaag ttaaagcatt
      841 tgcagaaaca gaagatgctg aagttgttgt agtatgtgca caaatagaag cagaaatttc
      901 tgaacttgat tctgctgaag aaaagaaaga gtttttagag acattaggtc ttgaacaatc
      961 agggcttgat aaacttataa aatcttctta tgctttactt ggtttaattt cattcttaac
     1021 tgctggtcca aaagaagtta gagcatggac tataaaagtt ggaagtaaag ctcctcaggc
     1081 aggaggaaaa atacattctg atatagaaag aggatttatc agagcagaaa caatagcctt
     1141 taatgattta gttgagcatg gtactatggc tgctgctaaa gaaaaagggt tagttaaatt
     1201 agaaggtaaa gaatacatag ttaaagatgg agatgtaata ttatttagat ttaatgttta
     1261 agatgattaa acatatacat tttgactatt atatgtatga taattagaaa attaaactta
     1321 ttgatagatt ttttattatc tctgtataat tatgtaaaat tttttaaaag agagatattc
     1381 taaatgatta ttataaatca tttagaatat ctctcttttt tacatagacg gtttctaaat
     1441 aacccacttt tggtctattc tttgcaggaa aaatcttata agaagccatt ccaacaatat
     1501 gaccagccac tatatcaaga aaagcatctt taggtttttt aatgccaaac tccctaccaa
     1561 tccaaaactt aatttaccaa gttcttacac aaaccttcct ttgtcatccg ccatttttct
     1621 aattttatac aagttatccc tcccaagttt ttaaataatt tttgatatac ttaattgtat
     1681 aaactctaca gttaatataa agttttatat cagaatactt catatacttt aaacaaatat
     1741 catctaactt gtaacttgtt attcctaaca atttatattc ttaataatag tacattttta
     1801 taaaaaaagt gaacattgat taaacaaagt tcactttttt taatttttat atggtatttc
     1861 ataagtttat ctaatttatt tcttttccct ttacactgta tctatctaat attaattttt
     1921 catattcttc tattggcatt ggtctagcaa acaaaaaccc ttgagccata tcacaaccta
     1981 taagccttaa aaactctgct tgctccacag tttcaacacc ttctgaaaca acttttatat
     2041 caagttgttt tgccatttga acaatacttg aaactacaat ttgactcttt tttgcatttc
     2101 ctactgttat aaagaattgc ctatctaatt tcaatacatc aattggcata tctttaagca
     2161 tatttaaaga agaataacca gaaccaaaat catccataga aattttaaat ccaacagatt
     2221 tcaaagtttg cattatttta aataatattt ttgtgttgtc aaatattgca ctttctgtca
     2281 attcaatctc aattaaattt ggctcaattt catattcttt tgttattctt tcaagctcag
     2341 aaataaaatc tggattctca agatgtactc ttgataagtt tattgatata ggaaatgtgg
     2401 ggaaattttc attttcccaa cgtttaaaat ttttacaaac ttgtgtaaat acaaacatat
     2461 ccaattctgt tataaaacca tttttctcaa aaataggaat aaatatacct gggcttatta
     2521 gacctttttt tggatgttgc caacgtacaa gcgcttcagc gcctacaatt ttagtagttg
     2581 ataaatcaac tttaggttgt aaataaactt taaattgttc attttttaaa gcatcatgca
     2641 tttcttgttc aatatcacgt tcttctatga gaatttcttt taaattttca gcataaatct
     2701 cataaacttt taaatatttt ctttttacag cagtttttgc aatcatagct ttgtcaagac
     2761 aggtagaaat attggtttct ccctcttcaa caaaatacac acctatagat ggaattaaat
     2821 tgagttctac tcccaaactt gtttttatca ttgacaattt tttacgtata agttcacata
     2881 tttctataat tgatgctcta ttatttttct tttcaaatat tatagcaaag ttatcatttg
     2941 aaattcttga aaatacagat tgctctttaa atatattctt aattatctct gctatttcct
     3001 ttaatactct atctccttct tcgtacccaa acctatcatt tactagttta aacttatcta
     3061 tatcaaaata aattaaaact agattctttt tctcatgaga ggataaaaat tttccccctt
     3121 caagattaaa tttatttgaa ttaccaatgc ctgtaacgtt atctttaaag gcaaattctt
     3181 ctaatttttc cttactcttt ttatgtataa atagtatata aattgttaat gctgtaaaga
     3241 ttataatcaa cactacacat gctgataatg taagttttat aatagcgtat gatttctcag
     3301 atatagcagc tttaggaact tcagaaaaaa gataccaatc attgattcct attggagcat
     3361 aacttaaata atatcctctt ccagacatac tataacttaa tgaacctgat ttaaagtttt
     3421 ttatatttga cttcatatta ttgatactag attttgatat tgaatcactt ttaccaatgt
     3481 aagaaaataa attttcttta gtagagttgg cgtttttact acttggattt aaaacaatat
     3541 caccattact tctagctaca taagaatatc cttttccatt aaatgtaggt acagaaagta
     3601 ttttttcata caacttcgta ctatgtgtag caaatataac tcctttaaca tcattatttt
     3661 tataaattgg tacagagtat acattaatat cgctattggt atttttatca tcttctatta
     3721 catctttcaa ctttcctgtt ataaccactt ctccttgcat tgattttaag aaataatctc
     3781 ttttagagaa gtcttctcta taaccatctg tagtgtatgc tgtaccattt ggtaaaataa
     3841 cgcccattct tttaaatgaa ctattaatag cttgtttttt cagtatagaa aggatattat
     3901 ctacttcaaa atactcttct ccttcaataa atattgaaat ggactctagt aactttatat
     3961 ctccattaat ttgttttttt aacacattga cgctttgatt tgctatttct gaaagatatt
     4021 gattcgtttc ttcacctaat gtcttattca accttgaacc ataaatcaaa caggaaattg
     4081 taattactaa gatacttatg acagcaatta tggacaaacc atacctatta ttttttgcat
     4141 cacttaacat tatgcttcct gcctttctca aatctatgta tgtataatca ttatcttatg
     4201 acaattattg taaacatttt ataataatac ttatttttcc atatttactg taattataca
     4261 aaattataaa ctttattaca acaataaatt aattaatgta gatattaggg tttatattat
     4321 tgcattatct atttacaatc atttacatat aaaaaatgta atatcaaagt aaaacttgat
     4381 attacatttt tgttcttgta ttttgtttac tttttatgct acattttact taaacactca
     4441 ttggcaactt ctttatcatc aaagtgatgc ttaactttac ctataatttg ataagtttca
     4501 tgccccttac ctgttataat tacaacatca tccttttttg ccatacttat agcttctgat
     4561 atagcttgtt ctctatcaac aacaacatgg taattttctt ttttcttgtc aattccttca
     4621 agtatatctt ttattattgc ttctggttct tcagttcttg ggttatcaga agttataatg
     4681 cataaatcag aatatttttg tccaattgct cccatcaaag gtctcttttc agtatctcta
     4741 tctccaccac atccaaatac agaaattatt tttccttctg caaattgttg agttgttttt
     4801 agtacatttt caagtgcatc aggagtatga gcatagtcta caattacact tataccttta
     4861 tcatttggaa ctgtttcaaa ccttccggat actccattag aaagtctaag accttcttta
     4921 tatattggtt tgggtatgcc aagtacatag caagcagcta taactgctaa agtattatat
     4981 actgtaaaca ttcctggaac tggtataaat attacttctt catatgaagg tgttattaat
     5041 ctataagata ctccatccga atctgatttt atatctctag ccataaaatc agcattagta
     5101 tcaaccccat aagtgtaaca aggtacattt atacctttta tattttcata tatctttttt
     5161 ccaccttcat catctatgtt tattatattt gccatagtag ttttaaaaaa taatttttct
     5221 tttgcttttc tataatcctc taaatcttta tgaaaatcta aatggtctgg tgttaaattt
     5281 gtaaatatgc ctagtttaaa atctgtttca tcaactctat ttaatgccaa tgaatgtgat
     5341 gaaacttcca tcgcacagta gtcacatcca ttatccaaca tattattaaa atgatattgt
     5401 aaatctatac tttctggagt tgttgaattg gaaacaatgt ctttttctcc gtcaaaaatt
     5461 tttatagtac ctataagccc aactttattc ttatttaaag ttaatatctc atttagtatg
     5521 gtagttatac tagtttttcc attagtacct gtaactccta taacgttaaa tttttgagat
     5581 ggatgattgt aaaaattatc agctactttt gccatatctt ttcttgtatc ttttaccttt
     5641 ataaatgtac atccttttat ttctacatct tcttcaacaa gaaaggcact tgctcccttt
     5701 tcaatagcat cttttatata cttatgacca tctgacacga atccttttat acatataaat
     5761 aatgtacctt ttgtaacctt tcttgaatca tattgtacat tattaatatc tatatttaat
     5821 tcacccttga cattgattat atccaacccc tgtataatat catttaattt cataaatgct
     5881 ttcctccctt taaactcttt ctgctaaaat tacactacat ataatattat attaagaatt
     5941 ttttactatg tgaatggtta aaaatgcttg aaacattgca aaaaatgctc tataattttc
     6001 tataatataa ctgaagaaag gtcttctata aaaactatgg ataataaaat cgggtactta
     6061 aatgataatt ttaaaatatt taatattaga gataaaaaaa atatacaatt tgaataccat
     6121 aatcatgatt ttaataagat aattatattt ataaatggaa atgtaactta ttttgttgag
     6181 ggtattcctt ataaactaaa gccttgggat atattattta tcagcaataa tgaaatccat
     6241 aaaccagtta tagattcaaa tgtcttttat gagagaattg caatatggat tagcccagaa
     6301 tttatgaaaa aaaatagtga tgctactagc gacttagaaa agtgttttaa aatatctaca
     6361 gagaataaat gtaatagatt gcgtttaaat atgcatgata ttgaatctat aaagagtttt
     6421 attgagcaaa taaatatttc tgaatccaat actgaatttg gaaatgaaat attgagaaat
     6481 gcattattta tacaacttat gatattctta aacagaattt tcctaaaaaa cgaaaatata
     6541 gaatcaacag aagacgtttt ttatgatgaa actattaaga aagtattaga ctatataaat
     6601 tcaaacatag atgataaact ttcaatagat agtatatcgt ctgaattttt tataagcaag
     6661 tattatctta tgagaaaatt taaatctcat actggaacgt ctatacacaa ctatatagtt
     6721 caaaaaagat tgattttggc aaagtcatta ataaccaatg gtcaccttat gagtgaagtt
     6781 tgtaataaat gtggattcaa cgattattct agctttgtaa gggcgtttaa aaaaaactat
     6841 ggtgtatctc ctaaaaatta tataaacagt aaaaaccctt tagacattac tcttttagat
     6901 gaatagataa tttatgtaaa ttttattttg ataaaaactt gaggtgttag tatatttatc
     6961 ttactagtac ctcaagtttt ttaatttttt aaaatatatc aaaatataat gatatatatt
     7021 tctattactt aaaatatata ctaactaaat tggatgttaa cttaacctat ttatgtgttc
     7081 attaaatctc atgtaacttt tagttatact atcatatagc tatcctattt tttcaatatc
     7141 gtctcttaat ataattactc tattctcctc ttttgctgta gttattcctt ttttaatgct
     7201 taatttctga ttttgttcta aattcgtaaa tactacaggg cttattgttg atagaccatt
     7261 tttttcaata tattctaagt ccattttaac taatttttct cctgctttta cttcatctcc
     7321 tacattcaca aatacttcaa atccatttcc ttctaagttt acagtttcta tccctaaatg
     7381 tataagtatt tctactccac tttttttgga ttttattatt attgcatgct tagttggaaa
     7441 tataactcca atagttccat caactgggga ataaatcaac ccatcattag atttaattgc
     7501 aaatccatcc cccatcaatt tacttgaaaa tacagaatct ggcacttctt ctatatctaa
     7561 tatctctcca tttgttaatg aataaatatt ttctactaaa gcattttcca tattggcaac
     7621 ttccatattt tttttcattt tatttttatc gttattttta ataacagcac tttcaatctt
     7681 tgtttttccc tctattatat cttttatatc agactttatt gaatccgatt ttggtccaaa
     7741 tataacttgc acattgttgc caataaccat aacacctgct gctccaagtg atttcaattt
     7801 ttctttatct actttattta tatcatttac aatcaatcta agtcttgtta tacacgcatc
     7861 tagactcttt aagttttctt tatttcctaa agcaaccaaa atctctgatg ctaattcatt
     7921 cttagacata tcaatgactt caacattagt ttctgaatca tcttctcttc ctggtgtctt
     7981 taaattaaac tttcttatca taaatctaaa tacactatag tataatactg caaaaccaat
     8041 acctaccaaa atagccaagt accatggagt tctattagga agaacaccaa ataataagaa
     8101 atctattaat cctcctgaaa atgtgaatcc aattttaact cctaataatt gcataactgc
     8161 gtatgataaa ccagaaaata aacaatgtat tgcaaataat actggtgcaa caaataaaaa
     8221 cgcaaactct attggctcag ttattcccgt taaaaaagat gttaatgctg ctgatgccat
     8281 tatacctgct acaaattttt tcttttctgg tttcgcttca tgcaccatag caagagctgc
     8341 tgctggaaga ccaaacatca taaatggaaa tgcacctgtc ataaaagtac ctgctgtgaa
     8401 atttacgcca tctttaagtt gagcaaagaa tatcttttgg tcacccatta caagctcacc
     8461 agctttattt acatattctc caaattgata ccaaaatgga ttatggaaaa catgatgcaa
     8521 accaaatggt attaataatc tttctaaaga accttccata aatgctgcta gtgtttgatt
     8581 tgcttctata acattttttg agaaactaag taatccctct tgtattggag gccaaataaa
     8641 agacaatata attcctattg ctatagcaac taatgaagta acgattggta caaatctttt
     8701 acctgcaaaa aaacctagat actgaggtaa ttcaatttta taaaactttt tataaagata
     8761 agcagccact atacctataa taataccacc aaatactcct gtttgaattg ttggtattcc
     8821 aacaatactt gcatacatag aattatctat catatcttct gtaacacctg ccataacacc
     8881 catagatgta ttaagaatta aaaaacctac tatagctgcc aatgctgcaa caccttctcc
     8941 ttcggtcaaa ccaacagcta caccaactgc aaatataagt ggtaagttat taaatataat
     9001 ttgacctgaa ctttccatta tacttattat aagttggaat gtagggttcg ctaaagctgg
     9061 aaaatgagcc aacaacgcat ctcctgctaa agcattactc acgccaagta atatacctgc
     9121 tgcaggaagt aatgcaactg gtagcattag agactttcct actttttgta aaacaccaaa
     9181 tacttttttc atttactttt ctctccttat tattttatat tttttaaata aaaaagactt
     9241 aagtttataa aaagttacat tagtatactt aattctaaaa ttaaacttat tttaatataa
     9301 ataaatctat attaacctaa tttcagaatt aaaaataaac tattataatt tttttataaa
     9361 cataagtctt gcctgcatta tcagtaacaa tcttaatgtt ttaaaattat tgttttatat
     9421 taaattttaa ataatatatt aaaattaaac ataatatact aaacctatac attttgtatt
     9481 aaactactct ttattataaa ttcaatacag atataactct tttgatatgt aatgttaaat
     9541 aaagtagttc atcttgactt acatagtaat cataattctt ttctacatga gtttttattt
     9601 tgtatgcaca attataatcc ttttcatact ttactttgat tatgtctata atttcattac
     9661 ttgtatcatt aattttttct ctttttacta accgttttgc aaagaatttt aaatgagtca
     9721 gaagcctatc ataatttata tcatcttctt taaattcaac tctataataa tatcttataa
     9781 tatttagtat gtcttttaca atcttagtaa ttaacaatga ttcctttgaa cttcctttat
     9841 agtttgaatt tactatatgc attgctataa aaccagcttc atccaatgga aactttaccc
     9901 caaattcttt atttatgtaa tctacagccc acttcccaat ctcatattct tttttatgta
     9961 ttctttttat ctcatgtagt aactcattct ttataattat attttcatga tatcttttaa
    10021 ttgcaaatgc aatatggtca gtaagtgcca cataaatata ttcataaagc ttagtattca
    10081 aattctcttc tgcataagca attatttcag tactaatcgc aaaaaatttc tcatcaacct
    10141 ggcttgctag tttaccaatt ttatctaaaa agctttcatc ttgtattata aaagttcttt
    10201 caattttatt tttatctatt tcttgacctt tctttttttg aaacccaatc ccacatcctg
    10261 ttagtattaa ttcttttttt atattttcat ctaaaactaa tacgacatta ttattataaa
    10321 tttgttgaat aatcataatc aatatctctc ccaaaataca atttccctta ttcataaaaa
    10381 aatacctaaa ttaagataca attcacctgt ataccttaac ctaggtattg cctgcttacc
    10441 agtaacaatc cagcctgtta acgcttatat attgtattca atttatggtt ttattctatt
    10501 ataaataaat atatatgtca agtaaattat tgaaaactat ttcctatttt ttgtattaat
    10561 tctaacatca aaaatcaaat tttattccat tatatttatg attctatcat catcatttca
    10621 tcatatagaa tattttccaa taactcttta gccacttctc ttgatatttg cttattttca
    10681 actaattgtt ggacactgtc tctttgactt tgtattgcca ttactctgta gtattctact
    10741 cttgactcaa acttatcatc attttgaatc tttctagtaa tccaattcaa ataacgatta
    10801 tagaatctga ttgatattaa ggcctcatgt ctgttatttt catcagtatt tttatttata
    10861 aatgatatag ccgttttagt agaaagtgca tatgcatagt gaaattcttt gattatttct
    10921 ttattctcag acactatttt tgtaattttt tcttttactt ctttctttac ttttctgtct
    10981 atagtccaca tacttatttt taattttata attttaaata tagatttttg aacagatttt
    11041 cttgattttg taatataaaa tctatacaat ttaaatgctc tatcagaaat tttaccatct
    11101 tctaatagtt tcaaaacagc caataatccc tgtttgtctg cttctgcaat catcatactt
    11161 ataagtttat tatctggagt atttaatatt cctttttctg agtctactaa ctgttcattt
    11221 aaatcatgta taactaattg tgcttcttgt gctttttcat tactaagttt taaaatggct
    11281 tctttcaaaa ttagtttata tgcctcttta tcagataata aatgttctga ctcttgtgaa
    11341 ttacttttta ataatcttgg cagtaaaact gttgccaata ttaaacttat aagaataact
    11401 tctgatgata taaataaaac agtatctctc attggaaata catctttatt agccaaatga
    11461 aatggtatag ataaggcagt agcgagtgta aacgtaccat gaacaccaca agtagcaact
    11521 attagtgagt atttacacct agaaatattc tcttttacag cttcttcatc cttaaaacct
    11581 aaaaaaccta caaaaaaatt atttaaagga ttctttttag tttttataaa agaatcatgc
    11641 cataaatata cccatataaa tcttataaca aataaaataa atacaattaa agcagaaata
    11701 aaggtcaatt tcaatgtcat atcttcattt ttactactaa gtcctgtata tatacttggt
    11761 aacagaaaac caagcagtgt aaagacaaac ccattcaata catactccaa aacataccaa
    11821 gtgttgtctg atattatcct taatttagta gttgtatttt gtaaatgctc tttttcaatt
    11881 ccatgagcta tccctgccat cacaacagct aggattccag atactcctac ttcctctgct
    11941 acaaaatata taaaaagtgg agtcattatt tgtataacta ttaccattgg aatttcttcc
    12001 aaattccact tatgtaggct aagtcttatt tttataatta tgtatcctaa aatacttcct
    12061 actattattc ctccaaaagc tgtaattata aattgaatcc ctgcctcttc tattgaaaaa
    12121 acgcctgtaa ctgtggcaag tactgcaacc ttaaatgcta ctactccagc agcatcattt
    12181 aataaagatt ctccttcaag tatactcatc atatttttag gaaaatttaa tccttgtgtg
    12241 attgatttta ctgctactaa atcagttgga gatattactg ctgccaaagc aaatgaaaca
    12301 gataatggca tcccaggaat aagaaaatgt ataaaaattc cacctgcaaa cacagttgtt
    12361 aaaactaaac caaatgcaag aagcaaaatt ggttttctaa gttctaacag ctcttttctt
    12421 gatacatttt gagcttcact aaatagtaat ggagctataa tacatatcac aaatatttct
    12481 ggattaaatg aaaataagaa tttaaatggc aaaatagata atataatccc taatacaatt
    12541 tgatatattg caagaggaat attattccac tttttgctaa atacagttga aatcgttgta
    12601 caaaccaata atcccaacaa tgttactaaa attgacataa ctacctctct tttcaataat
    12661 aatattatag attaaacttc tgtatcaact aacttaatat taacaacacg aaattccatc
    12721 ttcatcaaaa aattttcaat ttattctatt attcttatta tatacattaa atttaatttt
    12781 tgaaatatct atattagatg acatgcaaca aaatgatttc ttgatatttc ttttaaaact
    12841 ggaacctctt ttttgcatat ttccttacaa taagggcatc ttgtatgaaa cttacatcca
    12901 cttggtggat ttgttggaga tggtatgtct ccttttaata taattctatt tttcttaatt
    12961 gtagggtctt gtacgggtac tgcactcata agtgcttttg tatatggatg ttgagaatgt
    13021 aaataaagtt cttctttggt tgcaatttct attatagaac ctaggtacat aacacaaact
    13081 ctatgtgcaa tatgatttac tacactcaaa tcatgagata taaataaata tgagagttta
    13141 tatttgtcct gtaaatccat aagtaaattt ataatttgag attgaataga aacatctagt
    13201 gcggaaacag gttcatcaca aactataaat tctggattta atgctaatgc tcttgctata
    13261 cctattctct gtctttgacc tccagaaaac tcacctggtt ttctatttaa atggtactta
    13321 gaaagaccac aactttctac aatatttaat atattatctt ttatttcatt ctttggcact
    13381 aaatcatgtt ctataactgc ctcagatatt atttgctcca catttaatct tggatttaat
    13441 gaactatatg ggtcttgaaa tatcatttgc attttgggtc tcaactttct aagttcttcc
    13501 ttctctaact tatatatatc tataccatta aattcaactt taccttcagt tttttcaatt
    13561 aacctaagaa tggttcttcc tgcacttgat tttccacatc ctgattctcc aactatagcc
    13621 aaagtttctc ctttttttaa atcaaaagaa attccatcta ctgcctttac gaatttaatt
    13681 tctttgccaa ataatccaga tttaacttca aagtactttt taagaccttc tacttttaat
    13741 aaactctctt cttttttcaa ttatatctcc tcctttttat ataaccaaca tgcaatacta
    13801 tgaccactat tcaattctat taaaggaggt atctgagttc tacatttatc acatactttt
    13861 tcacatctat cactaaaata acatgaatct ggtattccaa ttggatttgg tacttgtcct
    13921 ggaattgaat ataatctttt atctttgttt tttccaagaa caggctttga ttttagaagg
    13981 ccaatagtat aaggatgctt tggattttta aacaattcaa caacctctgc tacttctata
    14041 attttgccag catacatcac tactacttta tcacacattt ctgcaactac tcccaaatca
    14101 tgtgtaatca tcattataga tgtatttaat ttttctttta tatttttcat tatatctaga
    14161 atctgagctt gaatagtaac atctaaagct gttgttggtt catcagctat aagtaatttt
    14221 ggattacatg ataaagccat agctatcatt attcgttgtc tcataccacc tgataattca
    14281 tgtggatatg aattatatat ttcttcagct cttggtattt ctaccagttt tatcatatct
    14341 attacctttt tcttagcttc ttcctttgat aaatcttgat gtaacataat accttcaatg
    14401 atttgacttc caacagtaaa tgctggattt aaagatgtca ttggttcttg aaaaatcatt
    14461 gatatctcat tccctcttat tctcataagc tcattttcat tcatctttaa aatgtctttg
    14521 ccttgaaaga ttatttctcc accttctatt tttgatgttg gaagtaactt catcaaagac
    14581 atggctgtta cagatttacc acatcctgac tctccaacta ttccaatagt ttcaccttca
    14641 tttatattaa aacttactcc atttacactc tttacaattc ctttatctgt atgaaaataa
    14701 acttttaaat ctttaacttc aattagtgct ttactcatta ttttctcctc tcagcaaaat
    14761 tgcttaaaat aacatacacc ttttgattgt attttataaa aatttaaatt acaacatttt
    14821 attacatttt attatttttt tctattaatt ataatattgt aatagttaat ttctatatat
    14881 attgatttaa taatgattat tattatacaa tgaaaaatat gtgttaaata ttattttatg
    14941 gaggttttat aagaatatga aatttaaaaa attggcatca ttaatcttag tttcagcatt
    15001 aatgcttaca tttacagctt gtgcttctaa tgataaagaa aagtctaatg gaggcaaatc
    15061 tggtggaact gttgtaatcc ctatggcaag tgaccctgat ataatcaatg gagcttttgc
    15121 aaatgttaaa gaagattctc ttgcatcaaa tatagtttat gctcctcttt atacttatga
    15181 aaaagggaat ttagtaaatt atctagcaga aaaagtagat tttaaagata gtaaggaatt
    15241 aactataaaa ttaaaatcca acttaaaatg gcatgatgga aaaccaataa ctgctgaaga
    15301 tgttttattt acatttaata cagttttaga cgaaaaacaa aattcaccat caagacaata
    15361 cttattggtg ggtgagaaac cagttaaagt agaaaaaatt gatgatttaa cagttaaaat
    15421 tactttgcca actgcaagtg aatctttctt atatggtata tctaaaattt ctcctatacc
    15481 aaaacatgtg tttgaaggag aatcaaatat agctaagtca gaaaaaaata ataatccagt
    15541 tggttctggt gcattcaaat ttaaagaatg gaaaaaaggt gaaagcatag tatttgaaaa
    15601 gaatgaagac tattttggtg gagaacctaa ggcagattct atagcactaa aaataatacc
    15661 taatgaagca tctcaagaag cagctttaaa taatggtgaa atttcactta tgaagacatc
    15721 tgcagaagga tatgaaaagg caaaatcaaa ctcaaactta caaacttata cttatagtga
    15781 agaaagatta aactacattg tatttaacca aaatatatca aacatggcta ataaagaagt
    15841 tagacaagcc ttatcatatg cattaaatag aaatgaaatg atagaatcag cgtatggaaa
    15901 agaaggctct gtacctgcta aatctatatt agttccagaa gcagacttct atacagaaga
    15961 aggtgttgaa ggatatgacc aaaatacaaa taaagctaaa gacttattgg ataagagtgg
    16021 tgttaaaatt gataaattaa aaatagggta taacacaggt agatttgggc ataaaaacta
    16081 tgctttagta gctcaacaag agttgaaaaa aattggtata gaagctgaaa tagttcctta
    16141 tgaaagtaag gcattcttca atatactatt tagtaatagc actgaatgtg atatgtatgt
    16201 aaatggttat gcttggggat tagaaccaaa tccatataga ggtatgtttg aaactggtca
    16261 atattgtaac caaactaaat attctaatgc taaaatagat gctttatggg aaaaaggatt
    16321 tactgagtta aacaaggaaa aacgtgaaga aatatataag caaatacaac aggatatatc
    16381 taaggatgca cctatttaca ctatagatta tgaacaaaat ttaatggcag ctcaaaaaaa
    16441 tctaaaagga atagaagatg ctaaaccatc tcctgcaata ttatttgaag attggtctaa
    16501 attgtatgta gaataattga tgtaaaattt tatattatta attagaaaag gagatgtcta
    16561 aaaataatat tgttttatta ttttaaaatg agacatctct tttaattagg agaatttact
    16621 tatgttaaaa ttaatattga atagagtgaa agttttaata cctatgttaa tcttaatatc
    16681 tatattatca tttggacttt tagaattagc tcctggtgac ccagcagatg catatataaa
    16741 tcctttaatg tctgcacagg atattgaaaa tataagagtt aatatgggac tcgataaacc
    16801 agtatacgta agatatttaa gctggttgaa aaacacttta agcggaaatt taggtatttc
    16861 ttatataaac catatgcccg taacagaaca aattatggaa aaaatgggaa atacatttat
    16921 tcttatgggt acttctttaa tattttcaat attggtagct atacctcttg gaatattttt
    16981 agctgtaaat aaaaattcaa taactagtaa aatatcatct atttttaatt atataggtgt
    17041 ttctatccct tctttttgga taggtatgat actcatttca attttttcag ttaaacttaa
    17101 catttttcca tcaggaggta tgcatactat tggaaatgat agtattggag atttagtaaa
    17161 acatctagtt ttgcctgtaa taactttagg tctatataat actgctattt ttacaaatta
    17221 tgtggaagct agtgtaaatg aacaattaaa aaaacagtat gttgttacag caagagcaaa
    17281 aggattatca gaaaaagtca tactatttaa acatgtcttg aaaaattcac tgacatcatt
    17341 ggttacaatc ctaggcatga gtatacaaaa attagttact ggcgcatttg ttacagaagt
    17401 agttttctct tggccaggta tgggaagatt aatgattgat tcaatttttt caagagatta
    17461 tactgtaatt atggcaataa ctatgttatc agcactattt ttaattttag gtaatttggt
    17521 tgctgatata ctatacttat tgattgaccc taaaataaaa tctagcaagg gaggattcta
    17581 gttatgttta caaatatctt aaaagaatta aaaaaagaca aatcctttgc ttttgcatgt
    17641 attactctta gtataataat catattaatt atagcttctt ttatattaaa tatagactct
    17701 aatgcaattg atactacttc taaacttcaa gaacctagct taaagcatat ctttggtaca
    17761 gatgaacttg ggagagatta cttctctaga gctctttatg gtggaagaat ttcacttagt
    17821 gttggtattt tatcaatgct tatttctgta gtatttggta ctgctgtagg tgttattagt
    17881 ggatatattg ggggtaagct agaccaattc ttgatgagac tagtagatat gcttatgagt
    17941 ataccaagct tcttagtttt gattgtatta aatacttatc taacacctaa aatttccact
    18001 attatactaa ttattggatt cttaagctgg atggaagttt caagaattgt acgtggcgaa
    18061 acattaaaaa taaaggaaaa tgaatactgt ctagctgcta aagctaccgg tatcaagact
    18121 agaaatatac tattaagaca tatagtttta aacttaaaag agactattgt agttgctggc
    18181 tcattaaata ttgctaatgc tatcttaact gaatctgctc ttagtttttt aggtcttgga
    18241 atccaattgc ctcttgcatc atggggtaat atgcttcaag atgctcaaaa atatattttt
    18301 gacaagttat atttagctgt atttccagga ctacttatat ttttaacagt tatgagtttt
    18361 actataataa gcaaaaaatt ttctagtaat acttaataaa ttttatatag aaaataaaaa
    18421 cagtgattat ccaaagatat acactgtttt tatttttcgt tttaaaaagc acatattttg
    18481 tataatataa ctttaaatac tactctagca tttatgtaaa acctgctatt gctctcaagc
    18541 acgtagatga aaaactaata gtttattata ataaaaatgg ttttatttat ttgttatttt
    18601 aataacactt ttaagagttc tttttactaa agaaatctat aataaattta aatacatgtt
    18661 ggtctacatg gctataacgt tcttttttag gtctacatag tacaactttc catgtaatag
    18721 gataattgaa aggtttttct ataattttgc tattttcaaa aaaatcatga actggtgatg
    18781 gtagaatggt tataaaatca gaatttgtag tcgatagcaa caaaaaatcc catgaaccag
    18841 acattatata tctctttagt ttaacatttt catcagtaaa tttttgcatt agcttatgat
    18901 gtatcataaa agtaggatta aatattgcaa gtaactgctc attcaaatcg ttccaatcta
    18961 tcttatcctt cttagcaagt ggatgattta tatttaaaaa tgctgtaagt tcatcttctt
    19021 gaagcacatg ttcagtcact acacttttat caattttatg tggatgtaat agcactgcat
    19081 aatctaattc ttgtaagata agcattctac ttaaatcata tgctcccctc tctactatgt
    19141 caaattctat atctggatta tttgcaacta actgtgcaac tacatctgaa aatactattc
    19201 caagtataag tggaggtatt cctattctaa tttttccttt aaattgaact gaatcttctc
    19261 ttaaatcttc catcatattt ttgtattcat ttataatatg ttctgcattt acataaaatc
    19321 tttcccctgc tggtgttaac ccatttaacc tacctttata cctttcaaat aaatatacat
    19381 cttcactttc ttcaaaattt tttataattt gacttagtgc tggttgagat atatgaagtg
    19441 tcttagatgc tattgataaa ttaaaaccag atttcactat ttcaacaaaa tattttaact
    19501 gttttatatc cattttaacc ccccttcccc aaaagtataa tttagattat attttttctt
    19561 ataatgatat tttataggaa aatcaacata atttcattaa tattttaaca aaatattttt
    19621 ctaaatctgc tctaaatttt tgtcctataa atttttctta tacactatat aaaaaattag
    19681 acttagacaa aacgcttttt tcgacgtaat ctataattag aaacaggaaa acctaaggca
    19741 ttgggaataa aaataattga aatacttaaa aacaagcttg tattagaagt actttattat
    19801 agtgttccat atttttctta ttcagaaaat ttttaattat cattcaagaa aggtaactat
    19861 tagatatgaa agacgtagta atcgtatcag cagtcagaac acccattgga aattttggag
    19921 gtgtatttaa aaatacttca gctgttcaac ttggaactat cactgttaag gaatcaattt
    19981 cacgtatagg acttaattta tctgaaataa atgaagtaat aattggaaat gtacttcaag
    20041 caggacttgg acagaatgtt gctagacaaa ttgctataaa tgcaggtatc ccaaattctg
    20101 tcccaagtta tacaataaat aaattatgtg gttcagggct taaaagtgtt cagctagctg
    20161 ctcaatcaat tgcatctggt gaaaatgatg tagtcattgc aggtggcact gaaaatatga
    20221 gccaagctcc ttatattgtt ccaactgccc gttttggtaa taaaatgggc gacataacca
    20281 tggtagacag tatgctaaca gatggtctta ttgatgcttt caatcaatat cacatgggaa
    20341 taacagcaga aaatatcgca actaaatttg aatttactag ggaaatgcaa gataaattag
    20401 cattagaaag tcaaaataag gctgagaagg ctataaaaaa caagcgtttt aaagaggaaa
    20461 tcattccagt gaatatctta atacgtcgtg gaaaaatgga aactattgac acagatgaat
    20521 atcctaaatt aggtatgaca tttgaaggtt tgtctaaact taaacctgca ttcaaaaaag
    20581 atggtactgt aacagctgga aatgcatctg gtattaatga tggtgcagcc atgctaatac
    20641 taatgagcaa acaaaaagca gacgaactag gaattaaacc acttgttaaa ataaaatctt
    20701 atgcttcagc tggtgttgaa cctgaaatca tgggtacagg tccaatccct gcaactagaa
    20761 aagcactgaa aaaagctggg cttagtatca atgatataga cttaatagaa gcaaacgaag
    20821 catttgctgc ccaagcatta gctgttaaaa atgaacttca aatagattca tcaaagttaa
    20881 atgttaatgg tggtgcaata gcattaggac atccaatagg agcaagtgga gctagaatac
    20941 ttgttacctt aatttatgaa atgcaaaaac gtaaagttaa aactggactt gcaacccttt
    21001 gtattggtgg tggtcaagga atatcaatgg tggtttcacg ataggaggaa atatgaataa
    21061 aatagttagt attgatgaag ctctatctca tgtaaaagat ggagatacaa taatggttgg
    21121 tggattcatg gccaatggtt caccagaaaa tttaattgat tatttatgta gtaaaaatat
    21181 aaaagatttg acactaattt gcaatgatac tggctttatt gacaaaggag ttggcaaaat
    21241 ggttgtaaat aagcaattta aaaagataat tgcttctcat gtaggattaa ataaagaaac
    21301 tggaagacaa atgaacaaca atgaaacaga tgttgagtta gttcctcagg gaactcttgc
    21361 tgaacaaata cgtgcagctg gttatggtct aggaggtata ctcacaccga ctggtattgg
    21421 tactcttgtt gaggagggaa agcaaaaaat tgttgtcgat agcaaagaat accttcttga
    21481 aaaaccaatt tatgcagatg ttgctcttct atttgcatca aaggtcgata aagcaggtaa
    21541 tctagtttat aaaggctcta tgaacaattt taataattta atggcatctg ctgccaaaac
    21601 tacaatagtt gaagcagatg aaatcgttga aattggcgat attgacccaa atgaagttaa
    21661 tacaccaggt atttttgtaa attacatcgt tgaaggaggt aatttataat ggataaatta
    21721 gaaatgcaag aatatattgc aaatagagta tctaaagaat taaaagatgg agctgttgta
    21781 aaccttggaa taggtctgcc aaccaaagta gcaaattata ttccagatga tgtaaacgtt
    21841 atcttgcaat ctgaaaatgg atttttaggt ttaggtgcag ctgaagatgg aaattcaaat
    21901 gatgaaacta ttgtaaatgc aggtggtcaa ccagttacta tactgcctgg aggatgtttc
    21961 tttgatagtg ctacttcttt tggaataatc agaggaggtc atgttgatat aactgttctt
    22021 ggtgcacttc aggttgacaa atatggcaac atagcaaatt atatgattcc aggtaagatg
    22081 gttccaggca tgggtggagc tatggacttg gtgactggag ctaaaaaagt tattgtagca
    22141 atggaacata cttcaaaagg ttctgcaaaa atattaaata attgcactct tccacttact
    22201 gcaacaaatg ctgtagattt gatagtcact gaaatggggg ttatggaagt aacatcagat
    22261 ggaattttac ttaaagaaat aaatccagct ttcacattgg atgatgttat ttcttctact
    22321 gaagcacctt tgatattgtc ggattcatta aatggaaaca tatctgttgt ttaaaataat
    22381 taaaactaga aaataaaaat gtcttagatg tattagatat aaatttatat tacttaaaat
    22441 attaatataa aaataaaata aaattggagg aaatgaaaat gcttaaagat aaagttgtat
    22501 tcgtaacagg agctgcaagt ggaataggta aacaaatagc tgaatcattc ttaaaaaatg
    22561 gtgctaaagt aatgttctct gatataaatc aagaagcttt aaataagacc acaacagagt
    22621 tacaacaaga aggttatgat tgcatgaatg taaagtgtga tgtaactaag gaagaagaaa
    22681 ttaaccaagc tatagacaaa actgttgaaa aatatggcag attagacata ttaataaaca
    22741 atgctggact tcaacacgtt tctatgatag aagatttccc aacagataaa tttgaattta
    22801 tgataaaaat aatgctaaca gcacctttta tagctaccaa aaaagcattt cctataatga
    22861 aaaaacaagg ctttggtcgt ataataaata tggcatcaat caatggtgta ataggatttg
    22921 ctggaaaggc tgcttataac tcagcaaaac atggacttat tggactaaca aaagttgctg
    22981 ctcttgaagc tgctgattct ggtataacag ttaatgcttt gtgccctgga tatgtagata
    23041 ctccacttgt cagaggtcag tttaatgacc tttcaaaaac tcgtaatata ccattagaaa
    23101 atgtcttaga ggaggtttta tacccacttg tgccacaaaa acgcctatta gatgttcaag
    23161 aaattgccga ctatgctatg ttcctagcaa gtgataatgc taagggtatt acaggacaag
    23221 cttgcttact agatggagga tatactgcac aatagttatt atatttaggg cttgaagaac
    23281 ttattcttca ggtccttcta ctaaggagga atatttatga gtattatcgc accaattggt
    23341 ataattattg gtatcatagc tattatatat ttttcagtta aagaaattca tataactata
    23401 gctgctccaa tagcaacttt aatagttgtt ctcttaaata aaatggatgt tgtaacatca
    23461 atgctaggtg ctgacaaaaa caattatatg ggggcacttg gaaactatat aatgagttat
    23521 tttgcaatat tcttattagg ttcaatactt gctaaattta tggaagaaag tggagctact
    23581 gtatcaatag ctgattttat tttaaataaa tttggttcta atcatcctta tagagtttta
    23641 gttgctatat ttatagtaag ttttatatta acatatggtg gtataagctt atttgtagtt
    23701 atgtttgcag ttattccact tgcaagaact ctatttaaaa agcttgatat ttcttggaac
    23761 cttattcaga taccactttg gcttggtatt gcaacaatta ctatgactat aattcctgga
    23821 acaccagcca ttcaaaatgt tatacctatt caatatctaa atacatctct tactgcagct
    23881 actataccaa gtgttgcagg tagtataggt tgtgctacgt ttgggcttgt ctacatgaaa
    23941 tatgctctaa acaaaagcat tagaaaaggt gaaacttatg caacttacac ttcagaatta
    24001 gaagaagaat ctttagctag ggaattacca ggattttttg caagtatttt tcctctatta
    24061 gcactcgtaa ttatagctat aactggaagt acttttggtt cagaatttat gaaaaaaaat
    24121 gtaatttaca tagctttaat agttgcaatt cttttatctg cttttttatt ccataaattt
    24181 ttatcatcta agatacagac attgagtata ggtgctagtg gttctatagg tcctatattt
    24241 gctacatctt ctgcagttgc atttggagca gtaataatgg ctgcacctgg ttttgatgta
    24301 tttagcaagc ttataatgtc aataccaggt agtccactta taagtcttac tgttttgact
    24361 tcaacaatgt cagcaataac agggtcatct tctggtgcat taggaatagt aatgccaaac
    24421 tttgcagatt attatttaag tactggtcta aatccagaat taattcaccg tgttgctaca
    24481 atagcctcaa atatactaac tatagttcca caaagtggtg tttttcttac attcctaagc
    24541 ctctctaagt taacacataa aactggattt aaagaaactt tcattgtagt tgcagttggt
    24601 tcactaatag cagaaatcat tgtaattaca ttaggattat taatgtatta atataaaata
    24661 aatcagaaat tacaatataa aagggaatgt ctcaaaatga attttttagt taatgagaca
    24721 ttcttttttg tatgaaatca catatacatt tattatttca acaatggaag tgaggctttc
    24781 tctattttga tgtagaccct tttattcctt aaagatttaa ataattataa tttgttacta
    24841 atattaaagc atttatttaa taaatttaac taaataaaaa aaaaatttat cataactata
    24901 aatttgcatt atagaattat tataaaaata ttatttgctc taaataagta attccatact
    24961 atacacactt ctaatacaaa ctgtcaaaca ctctgaaata tgcctaatta ttccatatat
    25021 gtctttttta catatcttta cagtaaaaaa atacttgaaa ttgtgttagt atagattcac
    25081 gggtaccccc tacactaaag gttacaaatt agtaacattt ttagaatttt tagattgaga
    25141 ggtgtttagt aatgagaaaa aatataccaa caaaattaaa aactatatta gctttaggag
    25201 tgttaacctt aacaacagct tccagtgctg ttaatgcaag tgctttatca cttgaaaata
    25261 atgtaaatac aagtaacaaa aatttagtat acagtaatac taggtacaaa ttttctgcaa
    25321 aaccaaattg ttctataaaa ccagaactta agcctgataa agacaactct tgcaaagata
    25381 agaatcatag tgacaaaaat tgcaacaata ctaataaacc tgataacaat aaaccagagt
    25441 ctaataaacc tgatgacaat aataattcag gttctactga taaacctgac aacaataaac
    25501 cagagtctaa taagcctgat gataataata attcaggttc tactgataaa cctgacaaca
    25561 ataaaccaga gtctaataag cctgatgaca ataataattc agactctact gataaacctg
    25621 ataacaataa accagagtct aataaaccta atgacaataa taattcagac tctactgata
    25681 agcctaatga taataacaat tcaggctcta caagtgaaaa tttttcagct taccaaaaag
    25741 aagttgtcga cttagtgaat atagaaagat ctaaagctgg attaaatcct cttactcttg
    25801 attcttctat atcaaacgtt gctacaaaaa aatctcaaga tatgattgat aacaactatt
    25861 tttcacacaa ttctccaact tatggttctc catttgatat gttgaaaaaa tttggaataa
    25921 gctataaaac agcaggtgaa aatatagcta tgggtcaaaa gacaccaaaa gaagttgtaa
    25981 atgcgtggat gaattctgaa ggtcacagaa aaaatataat gaatccaaat ttcagtaaaa
    26041 taggtgttgg agtagcacaa aaaagtggtg gttcaattta ttggacacaa atctttgtag
    26101 gataaaatac tctttttcca tacatatcaa aagggtatct ctaagtgata aaaaacacac
    26161 aaatgagata ctcttttgta tctatattta aaattattaa atacaaacat atatagtata
    26221 aatagtattg ttctctacca gtgattttga tgtacagaac aatatataaa aagtattggc
    26281 aatatgaaaa tggaaaactt aaaaaaggta tttagcagat aaaaacaaaa tcttaatatc
    26341 aaaaatgaaa aagagtcttg tcttaaaata gagacaagac cctttttcat tgttgatatg
    26401 attaaaatat attttatttt atataaaaaa gagtgcctca tgaactaaaa agttcacttt
    26461 gagacactct ttttatcaat tctatataag cattataata ctttaatatt attcagctaa
    26521 ttttttgtat ccttcatatc tttctttagc atcagcttca gctttagcaa ataatccatc
    26581 agcttcctct gggaattgtt tagctatagc agaatatctt acttgtgcaa gtatgaaatc
    26641 tttgaagctt gcagttggtt cttttgaatc taaagtgaat gggtttttac cttcagcttt
    26701 tacttctgga ttgaatctat ataaatgcca atatccgcaa gcaacagctt gtgcttcgtt
    26761 agctacagtt cttcccatac cttcttttaa tccatggttt atacatggag cataagctat
    26821 tattagagat ggtccatcat gtttttcagc ttctagaaca gctttgataa attggttttt
    26881 atcagcaccc atagcaactt gagctacata tacgtttccg tatgtcatag ccatcattcc
    26941 taaatctttc tttctagatt ttttacctga agcagcaaac ttagccatag cagcagctgg
    27001 agtagcttta gaagcttgac ctcctgtatt tgaatatact tctgtatcaa atacaagcac
    27061 atttacatct tcaccagatg caagaacatg gtctaatcca ccataaccga tgtcatatgc
    27121 ccaaccgtct ccacctagta tccattgaga tctcttaact agataatctt ttctatcttt
    27181 tatagctttt actaattctt tagctttttc atctgtacaa tcacaagctg gtttttctaa
    27241 taattcaaca accttagcac ttgctacttt agaagcttct ccatcatttc tagaatctaa
    27301 ccactctgta aatactgctt tagcatcttc acagatatcc atagaaacta gctctgtcat
    27361 agcatctact attttgtttc ttatttgctt aacagctgtg tacataccaa atccatattc
    27421 agcattatcc tcgaataaag agtttgccca agatggacct ttaccttcat ggttacaagt
    27481 ataaggaatt gatggtgcag aagctcccca tatagaagaa catccagtag cattagctat
    27541 catcattcta tctccatata attgtgtaac tactttaatg tatgcagttt ctccacatcc
    27601 agcacatgct cctgagaact ccattaatgg ttgtctaaat tgacttcctt taacagtatt
    27661 tgcaggcata acgtcaactt ttggagctac ttcatcagga tttactgcaa atgcccaatt
    27721 atctaactct gtatcaagtt gagtatctat tggcttcata actaaagctt tttctttagc
    27781 tggacatata tcagcacagt ttccacatcc tgtacagtca agtggactaa cttgaattct
    27841 atattttaat ccttctaatc ctttacctaa tgctttttta gcttcaaatc cttctggagc
    27901 attagctagt tcttcttcag taactaatac tggtcttata catgcatgag gacatataaa
    27961 agaacattgg ttacattgaa tacagttatc tattatccat tcaggaacat caacagctat
    28021 accacgtttt tcataagctg cagtaccaca agggaatgtt ccatcttcta taccattgaa
    28081 tgtacttact ggtaagttgt ttccttcttg tgcagtcatt ggtcttagta tattttttat
    28141 aaattctggt tctttaactt ctcctttatc tgcatcaaca gcattttccc aagaagctgg
    28201 aacttcaact ttaactaaag catttattcc tgcatcaaca gcagcatagt tcatgttaac
    28261 tattttttca ccttttttac cataagcttt aactatagaa tcttttaagt atttaacagc
    28321 atcttcttct ggtattattt cagctaattt aaagaatgca gattgcatta tcatgtttat
    28381 tctgtttcca agacctattt cttgtcctag tttaacagcg ttaactgtat agaattttat
    28441 atcattttta gctatatatt gcttcatatg agctggtaaa tgttcttcaa gtcctgcttg
    28501 gtcccatata gtgttaagta caaatgtacc acctttttta agacctttta ataaatcata
    28561 ttgataaaca tatgattgtt tatgacaggc aatatagtca gcttcatcta ttaaataagt
    28621 cgctcttatt ggactatcac caaatcttaa gtgagacata gttactccac cagatttttt
    28681 agagtcataa tcaaagtaag cttgagcgta tttttcagta tggtcaccga ttatttttat
    28741 agcttgctta ttagctccaa cagtaccatc agaacctaat ccccagaact tacatcttat
    28801 agttccttta gaagctattt ttattggttc agatggagtt aaagaagtat tagttacatc
    28861 atcaactata cttactgtaa atccattttt aggttgttct gaaactaagt tatcaaaaac
    28921 agtttttata tctgaaggag tagtgtcttt tgaacctaat ccgtatcttc cacctattat
    28981 cataggagca ttttcttttc catagaatac atcacgtaca tctaagtata atggttcacc
    29041 agttgaacct ggctctttag ttctatcaag tacacatatt ctttcaacag tagatggcat
    29101 agcatctaag aaatgtttca ttgagaatgg tctatataaa tgaactttaa ctaaaccata
    29161 tttttctccc ttagcattta agtaatctat agtttcttct attgtttctg ttacagaacc
    29221 catagccact aatacgtatt tagcatcttc tgctccgtag taatcaaata aactatgttt
    29281 tctacctgtt aaattactca ttttttccat gtatttttca actataccta ctatattttg
    29341 atagtattta ttagaagctt ctctagtttg gaagtatata tctgggtttt gagcagtacc
    29401 acgagcaact ggatgatttg gagataaagc attatctcta aatgcttgaa ctgcttcaaa
    29461 gtttaataaa cttgcataat cttcattttc taataattca actttttgga tttcatgtga
    29521 agttctgaat ccatcaaaga aatgtataaa tggtaatcta ccttctattg cagctaaatg
    29581 tgcaacaggt gctatatcag ctacttcttg aactgaacca gaagctaata atacacatcc
    29641 agtttgtcta gcagccataa cgtcttggtg atccccaaat attgataaag cttgagatgc
    29701 taaagcacga gcacttacat ggaatactcc tggtaataac tctcctgcaa ctttatacat
    29761 gttaggtatc attaataata aaccttgaga tgctgtaaaa gtagaagtta aagctcctcc
    29821 ttgtaaagaa ccatggaatg ttcctgatgc acctgcttct gactgcattt caacaacatt
    29881 aactgtttgt ccaaatatat tttttcttcc ttgtgatgcc cactcatcaa ctacttcagc
    29941 catagttgaa gatggtgtga ttggatatat agctgctaca tctgtaaacg cataggcaac
    30001 atgagctgca gctgtatttc catcaagtgt tttcataaac ttagccataa tatgtatcct
    30061 ccttgatagc tacaattgta cttgtttata acaagtctat ttttttatat ttacatataa
    30121 tttacacaac aaaaatataa acacacatat agtcgcgcaa atactctatc ttctaatata
    30181 atactacaga ttagataaaa ttcctttgaa aattgtaaat taattacata tttaagtaga
    30241 ttttttttta aattaaatat gttaagtttt
//
LOCUS       DAMKOJ010000047        28655 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000047 DAMKOJ010000000
VERSION     DAMKOJ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.049"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            176..1186
                     /locus_tag="PC592_002223"
     CDS             176..1186
                     /locus_tag="PC592_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF4056193.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGTALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGLALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALCDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     IF"
     gene            1322..1810
                     /locus_tag="PC592_002224"
     CDS             1322..1810
                     /locus_tag="PC592_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017825269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4056194.1"
                     /translation="MKITILYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTVVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FN"
     gene            1873..3801
                     /locus_tag="PC592_002225"
     CDS             1873..3801
                     /locus_tag="PC592_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4056195.1"
                     /translation="MVWHIEYEVFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIEKIPIFITFLLNQIYSLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLLICIILSITNPFTHILFGLSKETGYIRGCGYVATFSSFFFYAIYSALL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLVHIHDVNHVYRIGGDIFSIVVNSQLGIKPEDLIKKIEERFKKTWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKRKHVIKNCL
                     EEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFITIAEQTGLINL
                     IGLVVFEKVCRFIASDEFEGLKLDNIAVNLSVVQCMQKNLADDLLYLMDKYNISPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIGYSGVSNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PIPEDAFKNLLKENAFTG"
     gene            4000..4410
                     /locus_tag="PC592_002226"
     CDS             4000..4410
                     /locus_tag="PC592_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF4056196.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            4432..4734
                     /locus_tag="PC592_002227"
     CDS             4432..4734
                     /locus_tag="PC592_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF4056197.1"
                     /translation="MNKKIVAVCESERSLNSLKMAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(4906..5601)
                     /locus_tag="PC592_002228"
     CDS             complement(4906..5601)
                     /locus_tag="PC592_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF4056198.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKIDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATRLAILNATSKEIQKIKYTYLKSIEELDKVSQGLIEECYDADLQFHKEIILAS
                     HNPIFIRYYELIPKTISSNQYFGFKYRNSLKDMISHHNNIIIAFDSKDSNLGYTSMYN
                     HLEDVIQLFQHDD"
     gene            complement(5627..6814)
                     /locus_tag="PC592_002229"
     CDS             complement(5627..6814)
                     /locus_tag="PC592_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4056199.1"
                     /translation="MKKTSNQKLLLLSIVTFFWFSQYVYIPFQSPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFFPEGNGFLLAN
                     ILSGISSSTWISYMVHYTNFFSKEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKMPKKISIKKYLSICKDKRLIFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVISSGFASTKFCTKYEPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQRSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIRYGYFVLAIIAIVASILSYTYYKKLDLTLNYDI
                     IQS"
     gene            7150..7959
                     /locus_tag="PC592_002230"
                     /pseudo
     CDS             7150..7959
                     /locus_tag="PC592_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            complement(8089..9384)
                     /locus_tag="PC592_002231"
     CDS             complement(8089..9384)
                     /locus_tag="PC592_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019162973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF4056200.1"
                     /translation="MAKGSVRKKGKKWYYRFYVEDASGKMVQKEYAGTESKSETEKLL
                     RKALEDYENKKFVARAESLTVGELLDMWAEEELKAGTLSNGTVENYLGAIRCIKKHPI
                     ADRKLKTVTAEHLQSFLDLLTFGGEFPDGKVRKGYSKDYIHSFSAVLQQSFRFAVFPK
                     QLISFNPMQYIKLKRQAEEVDLFSDDEVEEGTQPISHEDYERLIKYLEKKNPPAILPI
                     QIAYYAGLRIGETCGLTWQDINLEEQCLTIKRSIRYDGTKHKNVIGTTKRKKVRIVDF
                     GDTLTEILKAARREQLKSRMQYGELYHRNYYKEVHVKNRVYYEYYHLDGTQEVPADYK
                     EISFVCLRPDGSLELPSTLGIACRSVSKKLEGFEDFHFHQLRHTYTSNLLSNGAAPKD
                     VQELLGHSDVSTTMNIYAHSTRKAKRDSARLLDKVASNA"
     gene            complement(9471..10100)
                     /locus_tag="PC592_002232"
     CDS             complement(9471..10100)
                     /locus_tag="PC592_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056201.1"
                     /translation="MKDKELRKLIGSRAKQRRLELNLTQPYVAEKMGVTASTILRYEN
                     GSIDNTKKMVLEGLSEALHVSIEWLKGETDEYETDITDKKELQIRDVMGDILKQLPLD
                     LNKTEDAFSKDLLLLMLKQYELFLDSFQFACKNYKGSTKDADIAKVMGFESKDEYNEI
                     MFLREITHTVNAFNDMADVVRLYSKKPEAAEQRLANLLSEVMYEDSESV"
     gene            10276..10506
                     /locus_tag="PC592_002233"
     CDS             10276..10506
                     /locus_tag="PC592_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056202.1"
                     /translation="MTQRKIALSIEEAADYTGIGRNTLRKLVEWKKLPVLKVGRKVLI
                     KTDMLELFMEANEGRDLRDKGNVKAVTRNGST"
     gene            10653..10967
                     /locus_tag="PC592_002234"
     CDS             10653..10967
                     /locus_tag="PC592_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxasome subunit MobC"
                     /protein_id="HDF4056203.1"
                     /translation="MARSTKSYEERMLQLEKREQESLEKAKQYAAQKRELKKRQKDVE
                     TKKRTHRLCQIGGAVESVLGCAIEEEDIPKLVGFLKRQEANGKFFSKAMQKEPVANTE
                     EV"
     gene            11296..13017
                     /locus_tag="PC592_002235"
     CDS             11296..13017
                     /locus_tag="PC592_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HDF4056204.1"
                     /translation="MAIFHYTVKIVGRSKGKSIISASAYLNGDVMKNEETGRISYYTS
                     KKEVVYTSLLMCENAPQEWQNVPAENIRRFQKSVRYKRADNQNAALEKFKLTFQKQRL
                     WNEVLRIEKSSDAQLGRSFEFSLPKEWSRQEQIDYTTEYIQKTFVDKGMCADWSIHDK
                     GDGNPHVHLLVTMRPFNSDHSWGNKEIKDWEFVRDENGNIVVDESHPDWWQDKKNPDR
                     HGIRIPVLDENGVQKVGTRNRKQWKRVLTDATGWNNPKNCELWRSEWANVCNAHLKTE
                     NHIDHRSYARQGKLEIPTIHEGADARKIDEKFQNGQTQSASWKVVENQIIKRQNALLD
                     KIQISFGKVSGALTQWKERLDDIRRKPGSHSHDGDNDKPDRGTAESYGSDGTGIAGTG
                     QATPVFSGAEPEFKKLKQRIIQAAKSFARYRRTALTDRATENQNRTVGKRESAMAGIN
                     AEAEQREQLIAETEQRIADLKQQIEKAREIDERMQKLRERRAGGRTSADDRTDAGRTG
                     SERPDNPGTKQAAKRIADLEREIEQRKQSREYRSIADKIKANRGTIDQRDRQQEKSRR
                     RSRGMEI"
     gene            13001..13705
                     /locus_tag="PC592_002236"
     CDS             13001..13705
                     /locus_tag="PC592_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004841175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056205.1"
                     /translation="MAWKFKYEKAEQEKLYAQTHQKTVEVAVEKKVPYEKCEKCDRTA
                     YRKAKEKCDSRKSQLEKKYKNMTIGYESILFLLAWYSITTTLFTAILSPVFLNDCIVF
                     FGALGKGMGSLFREFVTGADSFGQLSSGIPNSILSGIVYWLIAGTVMAILFVITGWLI
                     IGIGYQVGKIYRKYCWDIISIVVAITSTAVVIYFGEWIKNANPINLIVLLLLSHIIYI
                     GIRCYVKDWMEERGYY"
     gene            13861..14319
                     /locus_tag="PC592_002237"
     CDS             13861..14319
                     /locus_tag="PC592_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4056206.1"
                     /translation="MRKDNNMIIQLQRYYALWKECTAMYEEWSKDQGLSSNGIFALYS
                     FYESNGRCTQKMISEEWNIPKQTVNTILKDFQKKGYINMVSDDSDKRNKLICLTESGM
                     EYTKDIIEKLHSKEIYVIEKMGLENIESLNDNTELFIRLFKEGDCKKNES"
     gene            14309..15628
                     /locus_tag="PC592_002238"
     CDS             14309..15628
                     /locus_tag="PC592_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter MatE"
                     /protein_id="HDF4056207.1"
                     /translation="MNHKSLFFKYVIPSIIAFALSGIYAIVDGYFVGNTIGDAGLSAI
                     NIAYPIDALIQALGTGIGMGGAVYYSINAAEKKGKRAEEFIATSWWLLVIVSVISTII
                     IYSFSSKILGLLGADGIILTNATDYIKIIALGAILQILGTGMMPFIRNYGNSFWSMFA
                     MVGGFITNIVLDFIFVWIYEMGMKGAATATIAGQGVTAAIAIIYALYNKKFYVYVSLK
                     NVKEMCGAIFRVGLAPFGLALTPNISLVFINRFSASYGGEKAIATYACVSYIICIIYL
                     ILQGVGDGSQPLMSRFYGEKDQESLRGVQRMAYIFAIILAVCGGIIMYVNRANIGGVF
                     GASYEVSIEISKILPIFLVSLPFVAITRIATAGFYATEKSGLSYILTFIEPVLMLIFM
                     LVLPPLFGGQIMIWWSTVLARVFSAILAFILIKYCEKGDLQYGIQKI"
     gene            complement(15762..15998)
                     /locus_tag="PC592_002239"
     CDS             complement(15762..15998)
                     /locus_tag="PC592_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004844998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system protein"
                     /protein_id="HDF4056208.1"
                     /translation="MRTIFAEYNPQCNSIDVYTNTGYILRIDCWEAEKNLRTTPGSDC
                     ALTSLAIDEPLEYARLYLDGNLQMWVDAEDSLEL"
     gene            16286..17362
                     /locus_tag="PC592_002240"
                     /pseudo
     CDS             16286..17362
                     /locus_tag="PC592_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
     gene            17693..19099
                     /locus_tag="PC592_002241"
     CDS             17693..19099
                     /locus_tag="PC592_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF4056209.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYNNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGIDFYNKII
                     DKLIECDIEPFVTLYHFDLPFTLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMRYLEKRNIVPHM
                     EDGDKEVLKKAKMDFIAVNYYRTNCAGAFPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACRLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            19127..19975
                     /locus_tag="PC592_002242"
     CDS             19127..19975
                     /locus_tag="PC592_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4056210.1"
                     /translation="MYITKVLNNSLLLARDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLELPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSKEKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            20635..21327
                     /locus_tag="PC592_002243"
     CDS             20635..21327
                     /locus_tag="PC592_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056211.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEHIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKNDNYSKVHGLRAGADDYLTKP
                     FEIAEFTARVLSLIRRYTRFNPKNEESQQLSFKGLLIDLDQHTVTTNGETMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            21324..22259
                     /locus_tag="PC592_002244"
     CDS             21324..22259
                     /locus_tag="PC592_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4056212.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYIEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLDFEIDIPENRLMVNLDSDGYSRVVNNLVQN
                     VLAHSKARRIKITMSEDSKMVLLRVEDNGVGIAKENLQHIFERLYKCDKGRSKKGSGL
                     GLSIVSQMVERMGGKISVESEIGKYTVFIVSLPLI"
     gene            22409..23332
                     /locus_tag="PC592_002245"
     CDS             22409..23332
                     /locus_tag="PC592_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056213.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGSGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRNLCTERGKTILISSHILSEIALLADDIGIIDRGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLEIQLNLKNFKVADNHNIMLYDTDVSVAEINRAF
                     IQNNIDVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            23316..24086
                     /locus_tag="PC592_002246"
     CDS             23316..24086
                     /locus_tag="PC592_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056214.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIVFGIMFFVTALPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICIIYKKQEN"
     gene            24096..24878
                     /locus_tag="PC592_002247"
     CDS             24096..24878
                     /locus_tag="PC592_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056215.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQIVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFVITLIGGYLINREYTDQTLKNILTIPISLRKLLVGKL
                     IAVGGITVLLSIFSFLCTFILGLLFCNINISVILVAKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNSFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLAGYNNDDGSVYQPLI
                     GVMTLVVILILTAILLTFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            25256..25792
                     /locus_tag="PC592_002248"
     CDS             25256..25792
                     /locus_tag="PC592_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF4056216.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            25824..26213
                     /locus_tag="PC592_002249"
     CDS             25824..26213
                     /locus_tag="PC592_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF4056217.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLSQLTEHGFIKKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLKELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            26250..26636
                     /locus_tag="PC592_002250"
     CDS             26250..26636
                     /locus_tag="PC592_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF4056218.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNSVTVKVSSAIHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            26763..28205
                     /locus_tag="PC592_002251"
     CDS             26763..28205
                     /locus_tag="PC592_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF4056219.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDENIAEDIVEDEPKLNTEKDGDLNYVSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAKSKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGKDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            28502..28621
                     /locus_tag="PC592_002252"
                     /pseudo
     CDS             28502..28621
                     /locus_tag="PC592_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574155.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
BASE COUNT        10130 a         3902 c         5535 g         9088 t
ORIGIN      
        1 ataccacata ttttgggtat tgtatactag aattagatta attaatttat tttttaacat
       61 acaaatgatt ctgtgaaaaa aaacaagact caaaaatttt tatattcttt gatagaataa
      121 aattgagagt aaatttattg aattttataa aatttataag gggtgaatgt aagatatgca
      181 tgaagataaa aatgacatat ttgaatcaat agatactgag gattttgata ataaaacaga
      241 agaagaatgt ttagagctag taagaaaaaa tggattgaat ttaatataca taaaaaatca
      301 aacagaagag atatgcctag aggctgttag acaaaattgc aatgcaataa aatgtgttca
      361 gaatcagaca gaaaaaatat gtatagaggc ggttaaacaa gattggagaa tgttagaatt
      421 tgtggaagaa ccaacagaag aaatttgtat gttggctatt aaccaagatg gaacagcctt
      481 aaaatacata gaaaatcaga cagaagagtt gtgcctaaga gctgttgaaa aaaatggtac
      541 tgctttggag tatgtaaaag aacaaacaga agaaatatgt atagaagcag ttagaaatag
      601 tgaatttgga ttggcaagag tgaaaaatca aacagaaaaa atatgtatgg aagcagttaa
      661 acattgtagc tataatctaa aatgggtaga aaatcaaaca gaagaaatat gtatggaagc
      721 agttaggcaa aatgggcttg atttgaaatt tgtaaaaaat caaactgaaa caatctgttt
      781 aagagcagta agacaaaatg gattggcatt agaatttgta aaagaacaga ctgttggtat
      841 atgtttaaag gcagtaagac aatatggaat ggcattgaaa tttgtaaaag aacaaacgga
      901 agaaatttgt acagaagcta taaaacaaga taaaagggca cttagttttg taaaaggaga
      961 caaggaaaaa tacaaggctc tatgtgataa taatgaacca tttgcaaagc gatatgttag
     1021 aaatgtaata gaaaaagaaa atagagcatt gattaaaaaa ggtgaagaaa atgcaaaaat
     1081 caaaattgca ggaaaacttt atgatagagg tatgtctttt gaagatatat cagatatagt
     1141 tgagattgaa ataagcaagt taaaagtgag cttaggtatt ttttaagcta atagatgtag
     1201 gtgtttttta tgggaaatag ttaataaaaa aataatcgac gagttctttg tagtacagca
     1261 aaattagtgc tataatttga tatataataa attattttta ttagataagg gggaattaaa
     1321 gttgaagatt acaatattat accaaacaag aagtggaaac acagaaaggg tagctaagct
     1381 gatagaagat ggagctaaaa aggtagatgg agtagatgtt aaacttatga gacttgataa
     1441 tattgattta gattatttaa atgaaagtaa agcagtaata tttggaacac ctacttactt
     1501 agcaaataca acttgggaag taaaaaaatg gtttgatgaa gattcaaaaa aagtcaattt
     1561 agctggaaaa ttaggagctg tttttgctac atgtgattat atatgtggag gcccagatgt
     1621 tgctatactt actgtagtag gacatttgat ggttaaagga atgcttgtgt attctggagg
     1681 tggttcttta ggaaaaccat ttatacattt aggacatgta cattcaattg aaggtccaga
     1741 actacaagat gagaaggcta taatatttgg tgaaagaatt gctactaagg caaaagagct
     1801 atttaattaa tttctatatg cataatgatg attaaaatat ttaaaatcaa acgtcaatag
     1861 tgagggaagt ttatggtatg gcatatagaa tatgaggttt tttctgcaat tatagttatt
     1921 tttttaatgg tatacttttt tagaagcaaa tttataccta ctttacaaaa caaaatatat
     1981 tgtgcacttt taatattctc atttttattt ataatttcaa atattttagg ttcattttgt
     2041 ctaaataata tagagaaaat tccaattttt attacttttt tattgaatca gatatactca
     2101 ttgttattgc caataccagc agcacttgta tcattttatg ttatggctat tatttatcaa
     2161 gatataaggt atatgaaaaa aagattatta tttttatcta taccactttt aatctgtata
     2221 atcttatcta ttacaaatcc ttttacgcat attctatttg gattgtcaaa agaaacaggt
     2281 tatatacgag gttgtggata tgttgctact ttttcatcct ttttctttta tgcaatatat
     2341 tcagcacttt tatcttttaa atatagaaaa gcaatgcatg aatcaaaaat atgggctatt
     2401 agaggttttc ttatagtttc aattgtggca attatcttac aggcaatttt tttacagtat
     2461 cttcttacag gaactgcatg tgcatgtagt ttacttttga catatctttc tatgcagaat
     2521 cgaggtctta ttattgatga ccttactggt gtactcaata gacaatcttt tattcaagag
     2581 ctagatttga atatcaatac tgaacaatcg ggatttatta ttacaattgc acttgatgac
     2641 tttaagttca tgaatgaaac ttttggaaca aaaaatggag atattgcatt aaaagaagtt
     2701 ggaaaatatt tggttcatat acatgatgta aaccatgtat atagaatagg gggagatata
     2761 ttttctattg ttgtcaatag tcaattaggt ataaaaccag aggacctcat caaaaagata
     2821 gaagaaagat ttaaaaaaac ttggctagta gaagagataa gttttaattt agcaactagc
     2881 attgctgttg tttattaccc agaaaatgca gaaacgacag aagatgtaat tgttgctata
     2941 gatttctcta tacatgaagc aaaacgttct gagtcaaggc gagttgttta tgcagatgcg
     3001 tctataagtg aaaagataaa gagaaaacat gtgattaaaa attgtttaga agaagcatta
     3061 aaaaatgatg gatttgaagt gtattatcaa cctatatttt ctaatagcag aggtaggttt
     3121 acttcagcag aggcattact taggttggaa cataaagagt taggttttat accacctgat
     3181 gaatttatta caattgcaga acaaacaggg ttgattaatt taattggatt agtagtcttt
     3241 gagaaggtat gtagatttat agccagtgat gagtttgaag gtttaaaatt ggataatata
     3301 gctgtgaatc tctctgtagt acaatgtatg caaaaaaact tagctgatga cttgctttat
     3361 cttatggata aatataatat atcaccaact aaatttaaac ttgaaattac tgagacagta
     3421 gctatgggat cttttaatat aattaaagaa acaatggaaa gattaattga tttaggtgtt
     3481 aagtttgcac ttgatgattt tggaattggt tattctggag tttctaatat gctttcttta
     3541 ccgttttcag tgattaagtt agataagagc ttgatttggt ctatgaatga agacagtaga
     3601 cataagctta cagttgaaac gattatagct cttataaata aattgaatat gaaggctgta
     3661 gcagagggag ttgaaaccat aaaatgtgct gaagatttaa tagctatgga gtgtgaatac
     3721 ttgcaagggt attatttttc taaaccgatt ccagaagacg cttttaaaaa tttgttgaaa
     3781 gaaaatgctt ttacaggtta atacccttta tttttttaat tacaattttg ttcattgaca
     3841 ctgccagtta tatattataa aattaacaca ataataaata ttaaacttat tatacatatt
     3901 attaatatta attcatgaag taaagattta ttatatattt ttataactta gaatatatat
     3961 tttatttaat tatcctaaag tgagaaagga agatgtgaca tgaataaaaa gaaaatatta
     4021 gtgccaattg atgggacaga aagaagtatg cattctttgg aatttataaa aggaatattc
     4081 aaaaaagatg aagttgaagt agaaataatg aatgtaaaag aactagtatt tattgatggc
     4141 atatccctgg ctgaagagat aaaaaattct gaaaacttag gaagaagaat cttggataaa
     4201 gcagcagaga taatgggaga gtatgatgtt aaggtacatt ttacttttgg atatccagga
     4261 gacgagataa ttagaaaagc aaaagaagat aatgtagatt ttatagttat gacaaaatct
     4321 actaaaaagg gtcttacaag aatgataggt tcagtaacag caagtgtagt taaacaagca
     4381 aaatgtatag tgatgattgt accggagtag aattagaaag gtatttgaaa tatgaataaa
     4441 aagatagtag cagtttgtga aagtgaaaga agtttaaatt ctcttaagat ggctgcaaat
     4501 gatttagggt ttgacttagt ttatgaaatt caagaaaatg ataatataaa aaatgaactt
     4561 tctatttatg atatagaaga cgcatctata gtgttatttg ttacaagtga ttctatagaa
     4621 agtatagaga agattgatag atttatagat agagaatttt atgaagttga tccaaagtat
     4681 ataatagagg atgcaaagtc tatagtaagt gaaattttaa tagacttaaa ttaattaggg
     4741 gtgtctcaaa atgaactttt tagttcattt tgagacactt tttttctatg aaatcaaata
     4801 tatttttatc atttcaacaa taaaaatgtg attatctcta ttttgacaca accctttgag
     4861 ataattcatt tttgtatgac agttgtgctt aggaaaaata gaagtttaat catcatgctg
     4921 aaatagctga atgacatctt ctaaatgatt gtacattgat gtataaccta agttagagtc
     4981 tttactatca aaggctatta ttatgttatt atgatggcta atcatatctt ttagagaatt
     5041 tctatattta aaaccaaagt attgattaga agaaattgtt ttaggtatta actcataata
     5101 ccttataaaa attgggttat gagaggctag aattatttct ttgtgaaatt gtaagtcagc
     5161 atcataacat tcttctatca aaccttggga gaccttatcc aattcttcta ttgattttag
     5221 gtaagtatat tttatttttt gaatttcttt agatgtagca tttaaaattg ctagtctagt
     5281 agcttcactt tcgataagtt gccttgccct taaagattct acataaaatt cttggatgtt
     5341 atgattttta tagatttcac catcatcaaa taggtcaatt ttcttaaatc cttcaactat
     5401 aggacttgag taaggcacag ccctaagtat tccttcctta cagagtatat ttatggcatt
     5461 tcttacaggt attctactta tgttaaatag gtcagcaatc tttctctcac ttggtaattt
     5521 actattaatt ttaaaagttc catttagaat gtttaattta atataatcaa taattttttc
     5581 agtggcattt aagcttttca taaaaactcc taaatatata atttttttat gattgtatta
     5641 tatcatagtt aagagttaaa tctaattttt tataatatgt ataagataag atagaagcca
     5701 ctatagctat aatagctaag acaaagtatc catatcgtat tgaagtatat tccgatattt
     5761 taccaactat cattggaaat acagacattc ctatagcata aattgcttga aaaaagccca
     5821 ttgcagtaga cctctgatgt tttggtacat ttttcataga ctcgctagta aggtaagaaa
     5881 gaagtattcc tgtagatata cctggtagca cttgtagtac aaatattata ttgatatttt
     5941 ttattgttgg aactaaaaag cagtaggctg aaactaaaat aaaaactaaa ggaatccaaa
     6001 attttggttc atacttagta caaaatttag tagaagcaaa gccagaagaa ataacagcac
     6061 acaccatgta aaatatagaa gatagaccta taagggtaga actagaacct aagtttttaa
     6121 gaatttgagt ggtaaatgac attgttgtag acatttgaat accttgttga attaatgcca
     6181 taaaggaaaa aaatataagt cttttatcct tacatataga taagtatttt ttaattgata
     6241 tttttttagg catttttttt gaattatgat tttttatatt taaagctaga atcgttccaa
     6301 taactgaaga caatacactc ataatacata aggctgtcat tcctaatttt tcataaaata
     6361 aagtactcat aacaaatcca atcaacattc ctagattgtt taccagtatt atcgtacttg
     6421 tagctttttg ttgatgttct ttagaaaaaa aattggtata gtgaaccatg taagaaatcc
     6481 aagttgatga tgatattcca gataaaatgt tagctagaag aaaaccattg ccttcaggaa
     6541 aaaatactct tataagagat gccaaaccag caaagaaaat tccagatagt ataaatattt
     6601 tatgtttatt tattgaatca gcaaatactc caacaggaag tcttagtaaa cattgtgaga
     6661 ttccatatgc acctattatt ataccaatca tatttgtaga tacattgcat gcacttaaat
     6721 atggactttg gaaaggtata tatacatatt gcgaaaacca gaaaaacgta acaatagaaa
     6781 gtaaaagtaa tttttgatta gatgtttttt tcatattatc ctccatatgg tatatttata
     6841 atgcaaataa tataccattt agatttttta atcaagtact ttctctatta aaaaaaattt
     6901 aaatatataa ttattattta caaaaaaatt ataatttata gttgaattaa gaaaacgctt
     6961 atgatactat aaagttaaca aatttgaata tataacagta gacgtgttac tggtaatgca
     7021 ggcaagatcg aatcaatttt tatagattat ctatagagta ctatgggtat aatctattta
     7081 tttggttcga tttttttgtt taaatggcca taaaacaaaa agccgataat tgaaaatgga
     7141 ggatttttta tggattataa aaatatagct caagaaattc tactaaatgt aggaggaaaa
     7201 gagaatgtaa atgaagtgac tcattgtatg acaagactta gatttaaagt caaaagtgct
     7261 tctaaagtga ataaggataa attatctaaa attgaaggag taataactgt tgttgagagt
     7321 atgggtcaaa tacaagttgt aattggcaat aaagtaaaaa aagtatatga cgaggttata
     7381 aaaattgtac ctcaatcaaa tgaagtaggt aaaaagaatg aaagtgaaga aaagcaaggt
     7441 ataattaatt ctatattatc agcagtagct ggtatattta cacctacaat acctgctata
     7501 gcaggtgttg gtatgattaa aggtatctta tcagttcttg ctatgtatta tatgaataaa
     7561 aatggagtag atataaaaga aactcaaagc tatattattt taaatgctat ggcagattct
     7621 atattctatt ttatgcctat tatactagga tatactgcgg ctaaagtatt taatgcaaat
     7681 aaaataatat ctatggtatt aggagctaca ctttgttatc caacttttac tgctttgatg
     7741 gcaggtgaag aagctgttag atttttaggc ttggcagtaa caaaagctac gtatacatca
     7801 tctgttattc caataattat tgccatatgg gctctttcat atgttgaaaa agtattagaa
     7861 aagtatatac ctgaggtaat caaaataata atggttccaa ctttatcatt ggttataatg
     7921 ttacctgcaa cattattttt atttggacca atcggaattt gtggagagat ttcctgaact
     7981 ttccttattt tacaggcttt tcagcccatt agatagtgaa atgatatgta ttttccctta
     8041 tttttgccct tatgcggaat ccgtaaggga aataagggaa atttttgttt aagcgttgct
     8101 cgctacttta tcaagaagtc ttgcggaatc ccgttttgct tttcttgttg agtgagcgta
     8161 aatattcatt gtggtactga catcagaatg tcctaacagt tcctgtacat ctttcggagc
     8221 cgccccgttg gagagcaggt tgctggtgta ggtgtgacgt aactggtgga agtgaaaatc
     8281 ttcaaatcct tccagcttct ttgacactga cctgcaagca atgccgagtg tactcggcag
     8341 ttccagacta ccatccggtc tgaggcagac aaaggatatt tctttataat ctgccgggac
     8401 ttcctgcgtt ccgtcaaggt gatagtattc ataatacacc ctgtttttta catgcacctc
     8461 tttgtagtag ttgcggtggt aaagttcccc gtactgcatc cggcttttca gttgttcccg
     8521 tcttgctgct ttcaatattt cagtcagtgt atctccaaaa tcaacaatcc ttactttctt
     8581 tcgcttggtt gttccaatca catttttatg cttcgttccg tcataacgga tactgcgttt
     8641 tatggtcagg cattgttctt caaggttgat gtcctgccat gtaagaccac aggtttcccc
     8701 gatacgaagt cctgcataat atgcgatctg aatcggcaga attgcaggtg gatttttctt
     8761 ttccagatac ttgataagcc gctcgtaatc ctcatgtgaa atcggctgtg taccttcttc
     8821 tacctcatca tcagaaaaga ggtcaacttc ctctgcctgt cgtttcagct tgatatattg
     8881 cattggattg aaactgatta actgttttgg aaatactgca aaacggaaag actgctgtaa
     8941 cactgcggaa aaagaatgga tataatcttt gctatatcct tttcgcactt ttccatccgg
     9001 aaactcgcca ccgaatgtaa gcaggtcgag aaaactctgt aaatgttcag cggtaactgt
     9061 ttttaacttt cggtctgcaa tcgggtgttt tttgatacat cggattgcac caagataatt
     9121 ttccactgtg ccattgctga gtgttccggc tttcagttct tcttccgccc acatatccag
     9181 aagttctcct accgtaaggc tttctgccct tgcgacaaac ttcttatttt cataatcttc
     9241 cagtgctttg cggagaagct tttccgtctc acttttactt tcggttccgg cgtattcttt
     9301 ctgaaccatt tttccgcttg cgtcctctac atagaagcga tagtaccatt tctttccttt
     9361 ttttctaaca gatccttttg ccataaccgt atgtctcctt tcgatatcag acaatcggaa
     9421 ctgctgaaat gcttcttgcg tgtaagtata tcacaactcc ggttgtctta ctataccgat
     9481 tcagaatcct catacataac ttcggataaa agatttgcaa gcctttgttc tgccgcttcc
     9541 ggtttctttg aatagagcct tacaacatct gccatatcgt taaatgcgtt gacagtatgc
     9601 gtgatctccc tgagaaacat aatctcatta tattcatctt tcgattcaaa tcccattact
     9661 ttagcaatgt ccgcatcttt ggtactgcct ttgtaatttt tacaggcgaa ctgaaacgaa
     9721 tccagaaaca gttcatattg ctttaacatt aacagcagta agtctttaga aaaagcgtct
     9781 tctgttttat taagatcaag aggtaactgt ttgagaatat cgcccatcac atcacgaatc
     9841 tgcaattctt tcttatccgt aatatcagtt tcatattcat cggtttcccc tttgagccat
     9901 tcaatcgata catgaagtgc ttccgaaaga ccttccagta ccatcttttt ggtattgtca
     9961 atcgaaccat tctcataacg caggattgtg gaagcggtaa ctcccatctt ctctgcgaca
    10021 taaggctgtg tcagatttaa ttcgagacgg cgctgttttg ccctgctgcc gatcagcttg
    10081 cgtagttctt tatctttcat gctgatgtgc ctcctttttc ggtatgtcat tactatacca
    10141 cgcaataaaa tatattgcaa tatgcaatta atagaaaaag aataaaattt cataatgctt
    10201 gacaaagaaa tataaacacg ctatactgac agcacaaatt aaattgcata atgcaatcaa
    10261 taaggaggtg gtcatatgac gcaaagaaag atcgccttat ctattgagga agctgctgat
    10321 tatacgggaa ttggcaggaa caccctgcga aagttggtag agtggaagaa acttccggta
    10381 ttgaaggttg ggagaaaagt cctgatcaaa acagatatgc tggaactttt tatggaagcc
    10441 aacgagggca gggacttgag ggataaggga aatgtgaaag ccgtcacaag aaacggttcc
    10501 acttaaaaag gcggttcccg aagaaaccgc caaaggttct atcagaccgg agccatgata
    10561 tacctacacg caagcagatt ataccatgta cttcgtctga cagacaacag gaaacttatg
    10621 tttggtagaa aaaagaaagg acgatgatat ttatggcaag atcaacaaag agttatgagg
    10681 agcgtatgct ccagttggaa aaaagagaac aggaaagcct tgagaaggcg aaacagtacg
    10741 cagcacagaa acgggaactg aagaaacgtc agaaagatgt ggaaaccaaa aaacggacac
    10801 acaggctctg ccagattggc ggtgcggtgg aatccgtgct tggatgtgcg attgaggaag
    10861 aggatattcc aaagctggtc ggcttcttaa aaaggcagga agcaaatggg aaattcttct
    10921 caaaggcaat gcagaaagag ccagttgcaa atacggagga agtgtaatgc cggagggagt
    10981 ggagtttcca ttcccttcat tgctttttca tgaagggcgc acttatggac aaccagaggt
    11041 cgtccgtata agtttgccac aggtggcaac cggtctgcgc ttacgcttgc cgggctcgtt
    11101 ccgtcggcgg ggctttcagc cagacctgct catgccgcag gaggcactct tcgccagagg
    11161 ggcacattcc atgcaggctg ttatgcacag ggcactctta cgcagagggt gctccggcag
    11221 ataccatttt cttttaggaa aaacgttacc tgccggaaat caaagccgga tacggcagaa
    11281 tgggggaaac ggagcatggc gatttttcat tatacagtaa agattgttgg acgcagcaaa
    11341 ggaaaatcca tcatatcggc gtctgcttat ctcaatggcg atgtgatgaa aaatgaagaa
    11401 acaggcagga tcagctacta tacttcaaaa aaagaagtcg tttataccag cctgctgatg
    11461 tgtgaaaatg caccacagga atggcagaat gtacctgctg aaaatatcag acggttccag
    11521 aaatctgtcc gatataaaag ggcagataac caaaatgctg cactggaaaa attcaaactt
    11581 acttttcaga agcagcgttt atggaatgaa gtcttgagga tagaaaaaag ttcagatgca
    11641 caactcggca ggtcatttga gttctcactt ccgaaagaat ggagccgaca ggaacagatt
    11701 gattatacaa ctgaatatat tcaaaagacc tttgtagata agggaatgtg tgcggattgg
    11761 agtatccacg ataaaggaga tggtaatccc catgtgcatt tactggtgac gatgcgacca
    11821 ttcaattcag accactcatg gggtaacaaa gaaatcaagg attgggagtt tgtcagagat
    11881 gaaaatggaa atattgtggt ggatgaatcc catccggact ggtggcagga taaaaagaac
    11941 cctgaccgtc atggaatccg aatccccgta cttgatgaaa atggagtcca gaaagtcggg
    12001 acaaggaacc gcaaacagtg gaaacgtgta ttaaccgatg ctaccgggtg gaacaatccg
    12061 aaaaattgtg agctatggcg gagcgaatgg gcaaacgtct gtaatgcaca tttgaaaacg
    12121 gaaaatcaca ttgaccaccg ttcttatgca aggcagggga aattagagat accgacgatc
    12181 catgagggcg cggatgccag aaaaattgat gagaaatttc aaaatgggca gacacaatca
    12241 gcgtcatgga aagtggtaga aaatcagatc ataaaaagac aaaatgcact gctggataaa
    12301 atacagattt ctttcggaaa ggtatccggt gcattgacac aatggaagga gcgattggat
    12361 gacattagaa gaaagccggg aagtcattcc catgatggag acaatgataa accagatcga
    12421 ggaacagcag aatcttatgg cagcgatggt acaggaattg caggaacggg acaggcaact
    12481 cctgtctttt caggagcaga accagagttt aaaaagctta aacagcgaat tatccaggct
    12541 gctaaatctt ttgccagata cagaagaact gctctcacag atcgagcaac agaaaaccag
    12601 aatcgaacag ttggaaaacg agaatcagca atggcaggaa ttaacgcaga agctgaacaa
    12661 cgagaacagc ttattgcaga aacagaacag cgaattgctg accttaaaca gcagatagag
    12721 aaagcgaggg agatcgatga gcgaatgcag aaacttagag aacgtcgggc aggtggaaga
    12781 acttctgctg atgaccgaac agatgcagga cgaactggat cagaaagacc agacaatcca
    12841 ggaactaaac aggcagctaa gcgaatcgct gaccttgaac gagaaattga acagcgaaaa
    12901 cagagccgag aatatcgaag cattgcggac aagattaagg caaacagagg aacgattgac
    12961 cagcgagaca gacagcagga aaagagccga cgcagaagcc gtggcatgga aatttaagta
    13021 tgaaaaagca gagcaggaaa aactttatgc acagacacac caaaagacgg tagaggtagc
    13081 tgttgagaaa aaagtgcctt atgagaaatg tgaaaaatgt gaccgtactg cttaccggaa
    13141 agcaaaagaa aaatgcgata gccgtaaaag ccagttagaa aagaaatata aaaatatgac
    13201 gattggttat gaaagtatct tgtttctact ggcatggtac agcataacaa caacactgtt
    13261 tactgcgatt ctttcgccgg ttttccttaa cgactgtatc gtctttttcg gtgcgttagg
    13321 aaaaggaatg ggaagtttat ttcgggagtt tgtgacaggt gcagactctt tcggacagtt
    13381 aagcagtgga atacctaaca gtattctttc cgggattgtg tactggctga ttgccggtac
    13441 tgtcatggca attttattcg taataaccgg gtggctgata atcgggattg gttatcaggt
    13501 aggaaaaatc taccggaaat attgttggga tatcatcagt atcgtggtag cgataacgag
    13561 tacagctgtt gtaatttact ttggagaatg gattaaaaac gctaatccga taaatcttat
    13621 tgtattgcta ttactgtcgc atattattta tattggaatc agatgttatg tgaaagactg
    13681 gatggaagaa cgaggatatt attaaaagag gacagggaaa tttcataatc ttcctgtcct
    13741 tagtaaggga ctattgattg tttatataaa gaaaaagtat ataaataaat cttgacaatt
    13801 agtacgaact cggactataa tataaaagtc cggattcgta ctagtttaag gaggaaaaag
    13861 atgagaaaag ataataatat gataatacag ttgcaacgat attatgcttt atggaaagaa
    13921 tgtacagcaa tgtatgagga atggtcaaag gatcagggac tgtcttcaaa tggaattttt
    13981 gctttgtatt cattttatga aagtaatgga agatgcacgc agaaaatgat aagtgaagaa
    14041 tggaatatac ctaagcaaac ggtaaatacg atactaaaag attttcagaa aaaaggatac
    14101 atcaatatgg tatctgatga ttcagacaag agaaataagc tgatatgcct cacagaatca
    14161 ggaatggaat atacgaaaga tatcatagaa aaactgcact caaaagaaat atatgtaatc
    14221 gaaaaaatgg gattagagaa tatagaaagt cttaatgata atacagagct gtttatcaga
    14281 cttttcaagg aaggagattg taagaaaaat gaatcataaa tcattatttt ttaaatatgt
    14341 tattccatct attatagcat ttgcattatc aggaatatat gcgatagtgg atggatattt
    14401 tgtaggcaat accataggag atgctggact ttcggctatt aatattgcat atccgattga
    14461 tgctttgatt caggctcttg gaacaggaat tggtatggga ggagctgttt attactcaat
    14521 taatgcagca gaaaagaaag gaaaacgggc agaagaattt attgctacaa gctggtggct
    14581 tcttgtaata gtaagtgtta tcagtaccat aattatttac tccttttcgt ctaaaatttt
    14641 aggattgctt ggagcagatg gaattatatt aacaaatgcg acagattata tcaaaattat
    14701 agcacttgga gcaatattgc agattcttgg aactggaatg atgccattca ttagaaatta
    14761 tggaaactct ttctggtcaa tgtttgcgat ggttggtgga ttcataacca atattgttct
    14821 ggattttatc tttgtatgga tatatgaaat gggcatgaaa ggtgcagcca cagctacaat
    14881 agccggacag ggtgtgactg cagcaattgc aatcatatac gcattatata ataaaaagtt
    14941 ttatgtgtat gtatccttaa aaaatgtaaa agaaatgtgt ggcgctatat tcagagtagg
    15001 tcttgcacca tttgggctag cattgactcc taatatttca ttggtgttta taaaccgatt
    15061 ctccgcttct tatgggggag aaaaagctat tgcaacttat gcatgtgtat cctatattat
    15121 ctgtatcata tatctcatat tgcagggcgt aggtgatgga agtcaacctt taatgagccg
    15181 tttttatggt gagaaggatc aagaaagcct gagaggagtt cagagaatgg catacatttt
    15241 tgcaataatt cttgctgttt gtggtggaat tatcatgtat gtaaacagag caaatattgg
    15301 aggggttttc ggagcttctt atgaagtaag tattgagatt tctaaaattt tacctatatt
    15361 tttagtgtca ttaccatttg ttgcgattac cagaatagcg acagctggat tttatgctac
    15421 tgaaaaaagt ggattgtcat acattcttac attcattgaa ccagtattga tgctgatatt
    15481 tatgcttgtt ttaccacctt tatttggtgg acagattatg atatggtgga gtacggtatt
    15541 ggcacgtgtt ttttcagcga ttctggcatt catactaata aaatattgcg aaaagggaga
    15601 tttgcaatat ggaatacaga aaatttaaca atcagatagt agcaagaata atctaggttt
    15661 atctattgta tttttaagga cagcctcata gcaatagggc tgtcctttta aaattatgaa
    15721 gctaattttt aataaattct agtagatttt gattggaata atcataactc taatgaatct
    15781 tcagcatcta cccacatctg taaattccca tcaagatata accttgcata ttctaatggc
    15841 tcatcgattg caagcgatgt caaagcacaa tcagatccag gtgtggttct taaatttttt
    15901 tctgcttccc aacaatcaat acggagtata tagcccgtat tagtatatac atcaatgctg
    15961 ttgcactgtg gattgtattc tgcaaatatt gttctcatcg tatcccatct ccttatcatt
    16021 taatcaatca gtagtagcaa aaattaagaa gcatttcaat cagttcacca tgtcactttt
    16081 attttgtgtt atactgtctt atagattttt cttgcccttg tatttgccct tatcagagtg
    16141 cataaacact gatgggacga tataacacaa gggaaataat aagggaaagc tcacctgcga
    16201 caaatccagt gttttcaagg ggttgcgaag aatttaataa taaaatataa cagttattaa
    16261 atttcttaaa acaggtgaaa tctcaatcgg aatttatata ggaaatatca taaacttttc
    16321 ttataagtat atttatgaat taagcccagc attgtgtgga gcatttgtag gtggattatg
    16381 gtgtgtgttg gttatatttg gtgcacatag agcgctatta ccaataggta taagtgatgt
    16441 tgctcaaaca ggaagacaaa atttattggc atttgcagga gctgcaaact tttcacaagc
    16501 aggagctgct ctaggagtat tctttaaaac taaaaatcaa ggactaaaaa caatttctat
    16561 gtctgcaact ataacagctt tatttggtat aactgaacct gcaatatacg gtgccaatct
    16621 tagattaaaa aaacctatgg tatgtgctgt aatatgtggt gcagttggag gtgccataat
    16681 gggaatgggt ggagcttatg gtaatgcatt tgcaaaccaa ggtgttttaa ctatacccgt
    16741 atatgctgaa gcaggtgcat taggtttctt aagttatcta ggtggctgtg ctatagcatt
    16801 ttttggttca gctatttcaa cttatctagt tggatttgaa gatttggaag agtcttctaa
    16861 taaggaaaat tcatttataa aagtagaaac gaaagatggt gctattgata taacttcacc
    16921 tgtggaggga gaatgtatag aattatcaga ggtaaaggat gacgtatttg catctaaagc
    16981 tatgggagaa ggtatagcca tattacctac aaaaggagta ataacagctc ctactgattg
    17041 tgaagtagct tctttatttc caacactaca tgcaatagga ttaaaactag ataatggagc
    17101 agaaatgtta atacatgttg gaattaatac agtagagtta aatggtaaat actttacaaa
    17161 acatgtcaat caaggagatt tagtgaagaa aggtgataaa cttatatctt ttgatataga
    17221 taaaataaaa aaggctggtt atgatgtaac tacgccagtt atagtaaaca atacatttga
    17281 ctttggacaa gtagtttctt gtaaatctag ttatgtttca accaatgata atataatttc
    17341 attagtatta gctggtaatt aagttaattt gactagagat aagtaaatta acaattaaat
    17401 acatctaaaa gtaagtttat tgtaatgaat tattaaaaaa ataattaata tagagtaaat
    17461 ttattttaat gaagtaacaa agaaaatagt taatataaag tgaacttatt gtaatgaaat
    17521 aacaaagaaa ataattaata tagaataaat ctattgcaat gaagtaacaa agaaaatagt
    17581 taatataaag tgaacttatt gtaatgaatt attaaagaaa ataattaata tagattaaac
    17641 ttattttaat gaagtacaaa gaaaataatc aatataaaaa ggagaaatat ttatgaatac
    17701 aggatttcca aaagattttt tatggggagc atcatcttct gcatttcaag tggaaggagc
    17761 ttgggataaa gataataaag gaaaaaccgt agctgactat aattctttta aaaagtctca
    17821 tttacaggca gatactaaag tggcatcaga cttttacaat aattatgaag aagatattga
    17881 attaatgaaa gaattaggga tgaaaacata tcgtttttca atttcatggg caagaataat
    17941 accagatggt gaaggagaga taaaccagaa aggtatagat ttttataata agataataga
    18001 caaactaata gagtgtgata ttgaaccatt cgtaacttta taccattttg accttccatt
    18061 tacattagta gagaaatata atggctggga aagtagagaa actgtctatg cttttgaaag
    18121 atttgctaaa atatgcttta agcattttgg agatagagta aagtattggc aacctcataa
    18181 tgaacagaat ttaattgtta gagtggaaga gagaattaat atatatgatg aaacagattc
    18241 atggaaaata gataaaatgc gtgctcaaat ggactataat ctttgtttag cacatgcatt
    18301 agcagtcaat gcatgccatg agatgataaa agaaagtaaa attggagcag cagtatcatc
    18361 atctgtaaca tatcctctta cttccaagcc agaagatgta tatgcagcta gaatgaatga
    18421 taattttaaa gtgtactata tgcttgatat gcatcactat ggagaatatc cagggtatta
    18481 tatgaggtat cttgaaaaaa gaaatatagt ccctcatatg gaagatgggg ataaagaagt
    18541 acttaaaaag gctaaaatgg attttatagc tgtaaattat tatagaacaa attgtgcagg
    18601 agccttccca gaggattcac aacatccatt tgggttaaga gaaggaactg ttgattttag
    18661 tatgtatgga ttatttaaaa tgtcaatgaa tcctaaccta gaagcttctg agtatggagc
    18721 agcaatagac ccatcaggtc ttagagttgc cttaaatgaa tattggcaaa gatatcactt
    18781 acctgttata ataacagaaa atggtcttgg agctaaagac atattagaag atggaaaaat
    18841 tcatgatgac tatcgtatag attatttaag gagtcatata aatgcatgta gactagctat
    18901 tgaagatggt gtagagatga ttggatattg tccatggtca tttacagacc ttttaagctc
    18961 ttctcaaggt tttaataagc gttatggact tgtttatata aatagaactg accatgaagt
    19021 tttagatttg aaaagaatca agaaagatag tttttactgg tacaaagaag ttatagagaa
    19081 caatggaata gtaaaataaa cataaatata tattgagggt tttagtatgt acattacaaa
    19141 ggtattaaat aattcgttgc tacttgcaag ggatgataat gatgaagaaa taatattgat
    19201 gggaaaaggg attggccata attataaggc tgggtctgag ttaaataaaa aagatataga
    19261 aaagattttt gttcttcatg atgaaaatat aaaaaagagt attatacaac tggcaacaga
    19321 aatagatgca gaatattttg gtatagctca aatgataatt gcatatggaa tagaaaaata
    19381 taacttaaaa cttatgaacc atatatattt ggccttaact gaccacattg cctttgcagt
    19441 gagacgcttt aaagaaggta taatgattga aaatcactat ttgtttgaaa tcaaggagtt
    19501 taatccaaaa gagtatgata taggaaaata tgcaattact gtttttaagg aggttcttgg
    19561 tttagaacta ccagaagaag agattggtaa tatagcaggc cattttataa atgcacaaca
    19621 agataatcct tatagtgata gaaataagag aagtgctaaa attgtaaatg ctattttgca
    19681 aatagttcat tatcactttt ctattgtata taataaagag tcattttact ataggagatt
    19741 tgtaatgcat ctaaaggcct tttcacaaag atttctggct aacgaaccgt caaaagaaaa
    19801 aatagatttt atatatgagc aagttcaaaa aaattgtaag gaagagtatg aatgtgtgaa
    19861 aaaggtagga gcttatatgt ataaggaata ctccagagaa ttaccaagac aagaggagtt
    19921 atatttgatg attcatattc ataagatttt aggagaatta tgcgaaaata gttagaatat
    19981 cttaatatgc tagtaatatt ataaaaaatt aaaaattaat tacactttaa atatgaataa
    20041 ttgcattact taagggggtt gtcttaaaat tgattttttt aattaaattt taagttcaac
    20101 tcctttttaa acctttatat cattacaact ttaatgttta tacgcctgta cttcagatgt
    20161 gtatctattt tttacatttc tcaacatgaa aatttatcat tttttgtagt gtgttaattg
    20221 aaataaacct ttgagttaac cctaaattta ttctggacct acaggaatag ttccaaagat
    20281 actttaaaat attttctgga atgattgctt atttcatata tattttattg tgatgttttg
    20341 atttaataaa ttcttcaact ccgtatatag taaatgtatt atcatgtttg ttttatttaa
    20401 gcacacttat aatatgcttg attttttcaa aatgatgaaa tatactaatg ggtgttggat
    20461 gtataagaat cacattatac ttgaaaaagt aagtgagaaa tgaggtataa ttcctcatat
    20521 gataaactac tattgtattg tggaacatat tctcagtgat gtcaagatat tacaatatga
    20581 ctaaattcct aatgataaaa aagtctacga atgagtgtag aaaggggaac taagatgaat
    20641 aaagttttaa ttatagatga tgataaagat ctttgtattt tgttaaaaaa gagtatctca
    20701 attgaacata ttgaagcaaa ctattgccat tctgggagag atggattggt tgaactttca
    20761 aaacaagatt atcagttagt agttctagac gtgatgatgc caggtatgga tggttttgaa
    20821 actatggaac aaatacgaaa atatagcagt attcccatct taatgctgac atcgaaaaat
    20881 gataattaca gcaaagttca tggattgcga gctggtgcgg atgactatct aaccaaacca
    20941 tttgaaattg cagaatttac tgctcgtgta ctgtctttaa tccgacgtta cacccgtttt
    21001 aatccaaaga atgaggagtc acagcaactt tctttcaaag gtctgttgat tgaccttgac
    21061 cagcatacag tgactaccaa tggcgaaact atgttgcttc cacccaagga atttggtgtg
    21121 cttctttact gtgcaaggca tcagggtaag attttgacaa aacagcagat ttatgaagct
    21181 gtgtggggtg agccatatgt atatgatgac agcaatatca tggctattat cagtcgccta
    21241 agaaaaaaaa ttgaactaga cccatcatct cccatctatt tgcaaacgat aaaaggaatc
    21301 gggtatcaat tcaacacgga ggtatgaaaa tggatgaaca aacgataatt ctttttttgt
    21361 ttttgctgtc gattggtcta cttttccttt ccatatttgc tttttccaag cttggtcata
    21421 ttcacaaacg tctaaaagat atagaagaaa tacttgctga tgtacaaatt ggaaacgaaa
    21481 atcgaaaaat actaattaag ccatgtgatg ttatggctcc attggtttat cagcttaatg
    21541 agattgtcta cgattatgaa aataagttac tttctctgaa aaagtcggat aaagctagca
    21601 aacaacttat gacaagttta tctcatgatg ttcgtacacc attaacgact ctgattggtt
    21661 atctggatgc tgtacacagt ggtatagtta tcggacaaga acgggaggaa tacattgaaa
    21721 tcgctcggcg tagagcctac gaccttaagg attatatcga tgttcttttt gactggtttc
    21781 gattgaactc tgatgaattt acgttgtcaa tagaatctgt ggaaattgca gagttgtcac
    21841 gtaatattct taaagattgg attcctatct tccatgaaaa gaaattggat tttgaaattg
    21901 atattccaga aaatcgacta atggtaaacc ttgattcaga tggatattct cgtgtagtca
    21961 ataatctagt tcaaaacgtt cttgcccata gcaaggctcg ccgaatcaaa attaccatga
    22021 gtgaggattc taagatggta ttacttcgtg ttgaggataa tggtgttggg attgccaaag
    22081 aaaatttaca gcatattttt gagcgactgt acaagtgtga taaaggacgt tcaaaaaaag
    22141 gaagtggtct tggtttatcc attgtcagtc agatggtgga gcgaatgggc ggtaagattt
    22201 ctgtagaaag tgaaattgga aagtataccg tatttatagt gagcttacca ttaatataaa
    22261 aattgttttt cccccatgtg atatatatac acagggggga ttttttataa gctataaagt
    22321 tgcaaggtta atacaaggtt gttgcaaggt taatgtaaga ttgaggtggt atgataaatt
    22381 taataaacaa aggaggattt tactatttat gaataattta attattgaaa caaaaaatct
    22441 cactaaacaa tatggtgctc aaaagagcgt ttctaatttg aatattcatg ttcagaaagg
    22501 tcgtatttat ggattgctgg gaagaaatgg ttcgggtaag acgacaacta tgaaaatgtt
    22561 attgggtcta acaaaaccaa ctactggaga aattaaaata tttggtcagg atattcataa
    22621 taacgagaaa aagcttcttc ctagaattgg atgtttgatt gaatcaccag gtttttatcc
    22681 taatctgaca ggaacagaaa atctcaaaat ctttgcgagg cttagaggaa taccaaaaaa
    22741 aaatgcagta gaatcagcac tggatgtagt cggtttgcca aacaatgaca aaaagttatt
    22801 ttctcaatac tctcttggta tgaaacagag gttggcaatt gctcttgcca ttatgcatga
    22861 cccacaattg ttgattttgg acgagcctat caatggactt gatcctattg gtattgcaga
    22921 agtaagaaag tttattcgta atctctgcac agaacgaggt aaaactattt tgatttccag
    22981 tcacattctt tctgaaattg ctttgttggc agatgacatt ggcattattg accgtggcat
    23041 tttgttggag gaagaaagcc ttgcacaact ggaagaaaaa aacagtaaat acatacattt
    23101 tgctgtatct gatgcagcac aagcagcaag acttctggaa atccagctta acctgaaaaa
    23161 tttcaaagtg gcagacaatc acaatattat gctttatgat acagatgtct ctgttgcaga
    23221 aataaatcgt gctttcattc aaaacaatat tgatgtatca gaatctcatt tgtgcgaaga
    23281 tactcttgaa gattacttca agaaagtaac agggggtgaa ggaattgctt gatataattt
    23341 catgcgaatt ttcaaaactc aagcggttaa aatttatact gatttctatt ttaggtgctt
    23401 gtttatttcc aattcccgca acaattttga ttgcaaagga caacttgcct tttgagcaat
    23461 tgttcaaatt agttgtcaat tttggatatt ttttgctatt accaattgta ttgagtattg
    23521 ttgctagcca actctttttc atagaaagag ataacgatgt attaaaaaat ctagcaacag
    23581 tgccagtgcc aaaaggaaaa ctggctctgg caaaattagc tgtgttgctg tttatatcat
    23641 tgttctactc cgttgcaggg ttaggagcta ctatcatagg aggtttcatt gttggaatag
    23701 tagagggggt tgctgtaaaa ttaggaatga gtattgtttt tggaattatg ttttttgtta
    23761 ctgcacttcc tgttgtggta ctcattgtat atttcaatcg cagctatatt ttttctatta
    23821 tactttcttt tgtatatgct attttcaatt ttagtatatc cttaaatatt atcaactttg
    23881 aaccaaataa cccactgtta agcgtattac ctgctcctgt tataatgcgt tggtggatgg
    23941 cattttgggg agatcccact ggcgaataca cggcacttag acagccatat ttactctcaa
    24001 ctcctgcttg tgtaggtatt ttatgtttga taacaattat tgcagtcctg ttgatttgta
    24061 taatctacaa gaagcaggag aattaggagg tatctatgct tgatataatt actacagaat
    24121 ttcaaaaaat aaaaagatat aatattctat ggattggtgt tgttgctgtt ctgttttcag
    24181 cactattggc ggtttttcag attgtaagtt cacacggcag tgaccctcta acgtatgaga
    24241 gctttgcaaa tggagttata tggaataatt tcagtcttag ttttccattt gtgattacgc
    24301 tcattggagg atatcttatt aaccgtgaat atacagacca aaccttaaaa aacatcctaa
    24361 ctattcctat ttcattacgc aaattgctag tgggaaaatt aattgcggtt ggaggaatta
    24421 ctgtattgtt aagtattttc agcttcttat gcacatttat tttagggtta ctattttgca
    24481 atatcaatat atctgttata ctcgttgcaa aatccttagt tcagattttg tctgttaatc
    24541 tgtattgtta tgttgctgtt ttgccgatta ttgcttattt tggtcgtaaa caaaattcct
    24601 ttttgacagg cgtagggatt gcatttgtat atggcttctg tggtgtattt gttgctggaa
    24661 gaaatctaac agacttttat ccaatcacag caggtcttgg tctagctgga tacaacaatg
    24721 atgatggtag tgtttatcag ccacttatag gtgttatgac tttggttgta attctaatcc
    24781 tgacagctat tctacttaca tttacaccta attacgataa agttatgacc atatctaaga
    24841 aaaaagggat aaagcataaa aagtattctc ataaataaca taaatattgt ttctattatt
    24901 taagttgtca ggcagtgaaa agaaaaaatc tgtcgtacag tggctatatg ctcatgtatt
    24961 taagaagcta cagttttgat ttttcatagg tgtggcttct ttttgtattt attaaatcaa
    25021 caactatcat aatatttgca ataggtatag taacaagaga taatactgtc atatgtgttt
    25081 tatatattac attaagtata ttctaaaata tatgttttaa ataatatatt tgaaaataag
    25141 aatacttgaa taaaaaaaat aatattatat atagttgaca aaaagtggaa attaatatac
    25201 tatataaata tagaaatagt aatcattact aatattaaaa aaggaggaat taattatgaa
    25261 cttaaaagga actaaaacag aaaagaattt aatggcagga tttgcaggag agtcagaagc
    25321 aagaaataaa tatacatact acgcttcaaa agctagaaaa gaaggttata atcaaatagc
    25381 tgctatattt gaagaaactg ctaacaatga aaaggaacat gctaaattat ggtttaaact
    25441 tttacatgat ggtatgcctt caacagagga aaatttaaag gatgcagcag caggcgaaaa
    25501 ctatgagtgg actgacatgt atgcgaaatt tgctaaagaa gctagagaag aaggatttga
    25561 caagatagct tatttatttg aggctgttgg aaaaatagag aaagagcatg aagaaagata
    25621 cttaaagctt ttagaaaact taaatgaagg aaaaatattt aaaagagatg aagaagttgt
    25681 ttggcaatgt caaaactgtg gtcatgtgta tgtaggtact gaagcaccag aaaaatgtcc
    25741 agtatgtgac catccaaaag catatttcaa tataaaagct gaaaattatt aaaaattatc
    25801 attattaaaa aggaatgtta actatgaaat tttctaaaca acgagaactg attttgaatg
    25861 aaatattaaa taatccggtt catcctactg cggattacct atatgaaaac ttaaaaaaag
    25921 ataatccaaa tctaagctta ggaactgtgt atagaaattt atctcaacta acggaacatg
    25981 gctttataaa aaaggttagt attccagggt atccagatag atttgatggt agaatagata
    26041 atcactatca tatcatatgt gaagtatgtg gagaggtata cgatttagaa tctgaagttc
    26101 ttaataattt aaaagaatta atatctgagg agacagacat aaaaataaca tcttataaca
    26161 taagttttaa agggatttgt aataattgta aaagatgtag ccaagtaggt tagcttttaa
    26221 attctaaaaa taattaatga ggtgagttta tgtgtagcga acaaaaattt tttatatgtg
    26281 agacttgtgg aaatcttgta ggaatgatac aaagtggtgg tgtacctatt ttctgttgtg
    26341 gaaaacctat gaaggagctt gttcctaata caacagatgc agcagttgaa aaacatgtac
    26401 ctgtgattga agtggatgga aatagtgtta ctgttaaagt aagtagtgca attcatccaa
    26461 tgactaaaga acatcatata gcatgggtgt atcttatgac tgaacaaggt ggtcaacgca
    26521 aatgtctagc agtagatgga gaacctgtag ttaaatttgc tctgaatgat gatgataaag
    26581 tgatttctgc atatgcttat tgtaatttac atggtttatg gaaggctgaa ctgtaatatt
    26641 taaataaatt gagtcaaaaa ggaggctata aatgtatttt catacaaata gcctcctata
    26701 aatttatata aattcgagtt ttaattttat ttaatgtcaa tataatataa ggagaaaata
    26761 atatgtcaat ttacaaatgt agcgtttgcg gatatattta tgatgaatct aagaatgata
    26821 aaacatggga tgaattaagt gaagactggg aatgccctgt atgtacaaaa ggtcgtagtt
    26881 attttggaaa gataagtact gtttactatg aagaagatga aaatatagca gaagacatag
    26941 ttgaagatga acctaaatta aatactgaaa aagatggaga tttaaattac gtaagtacat
    27001 atttaagaag agatgatgaa gttgagaaac atatggatat aattcacgaa atggctgtta
    27061 caggaaaatc tataatagaa ccgatgagaa ctaaactacc agtaatttct tgggatgata
    27121 ttttaattat gggtgctcaa ttaaatccat tacctttaaa cgaacatgat gaagtaaata
    27181 caacaacaat aatagggaaa aaagcaaaga agcctatgat tatagaaaat ccagtttata
    27241 tttcccacat gtcatttgga gctttatcta aagaactaaa aatagcttta gcaaagggtg
    27301 ccgctaaaag taagacagct atgtgtagtg gagaaggtgg tatattacca gaagaaaaag
    27361 aagcttcata taagtatatt tttgaatatg taccaaataa atatagtgta actgaagaaa
    27421 atcttaaaaa ttctgatgct atagaaataa aaattggtca aggaacaaaa cctggtatgg
    27481 gaggtcatct tcctggtgaa aaagtaactg aagaaatagc aaaggtaaga aataagcctg
    27541 taggtaaaga tgtaataagt ccatcttgtt ttgaggaaat acaatccaaa gaagatttaa
    27601 agaaacttgt agatgaactt agagaagttt cagaaggtcg tccaataggt gttaaaattt
    27661 cagctggtca tattgaaaaa gatatggaat ttatagctta tgctaaacct gattttgtga
    27721 ctattgatgg tcgtggtgga gctactggag caagcccaaa gttgcttaaa gatgcaactt
    27781 caatcccaac aatatttgca ctttatcgtg ctagaaaata catagataca catggattag
    27841 atatagattt ggttataaca ggtgggcttc gtatatctac tgattttgcc aaggcaattg
    27901 ctatgggtgc tgatgcagtt gctattgcaa gttctgctct tatggcagca gcatgtcaac
    27961 aatatcgtat atgtggttct ggtaagtgcc ctgtaggagt agctactcag gatgaggaat
    28021 tgagaaaaag attacatata gaaaatagtg ctaatagagt ggcaaacttt ttaaatgtaa
    28081 gtttagaaga acttaagact tttgctagaa tttctggtca taaagatata catgatttaa
    28141 gtgttgatga tttatatact gttaactctg aaatatcaaa ttacacaaac atacaacatg
    28201 tataagttga agtttgagac tattagattg tagatagtta taaaagtaaa tgataaatat
    28261 attttataaa aaggagtgtc ttaaaatgaa ctttttagtt tataagtcac tcttttttgt
    28321 atgaagccaa atatatttat cattttaaca atgaaaaaga atcttatatc tttactttga
    28381 gatagattcc ttctatttat gaaaattaaa gatattaaat tgtaaaacat tctgtgatgt
    28441 cgtactatta aactaaagat gctgtacttt aaagtaaata aaaatttaag gagtgattat
    28501 tatggaaaaa ttgaagattc aagttctagt tgacaataat acatatattg ataggtactt
    28561 tgttggagaa ccagcagtaa gctattacat tgagattgat ggaaatagga ttttgtttga
    28621 ttaaaaaata gctacgaaca cttgtgactt tagtc
//
LOCUS       DAMKOJ010000048        28621 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000048 DAMKOJ010000000
VERSION     DAMKOJ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.050"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            34..687
                     /locus_tag="PC592_002253"
     CDS             34..687
                     /locus_tag="PC592_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF4056220.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLAKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            828..2099
                     /gene="brnQ"
                     /locus_tag="PC592_002254"
     CDS             828..2099
                     /gene="brnQ"
                     /locus_tag="PC592_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF4056221.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAIFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            2301..3488
                     /locus_tag="PC592_002255"
     CDS             2301..3488
                     /locus_tag="PC592_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HDF4056222.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKVIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINAEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNDYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISKKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSLAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            3978..4292
                     /locus_tag="PC592_002256"
     CDS             3978..4292
                     /locus_tag="PC592_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF4056223.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            4308..4694
                     /locus_tag="PC592_002257"
     CDS             4308..4694
                     /locus_tag="PC592_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF4056224.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            4723..6108
                     /locus_tag="PC592_002258"
     CDS             4723..6108
                     /locus_tag="PC592_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF4056225.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            6111..6263
                     /locus_tag="PC592_002259"
     CDS             6111..6263
                     /locus_tag="PC592_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4056226.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            6286..7491
                     /locus_tag="PC592_002260"
     CDS             6286..7491
                     /locus_tag="PC592_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF4056227.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            7534..7755
                     /locus_tag="PC592_002261"
     CDS             7534..7755
                     /locus_tag="PC592_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056228.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            7872..8369
                     /locus_tag="PC592_002262"
     CDS             7872..8369
                     /locus_tag="PC592_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF4056229.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            8344..8850
                     /locus_tag="PC592_002263"
     CDS             8344..8850
                     /locus_tag="PC592_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4056230.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            8834..11281
                     /locus_tag="PC592_002264"
     CDS             8834..11281
                     /locus_tag="PC592_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4056231.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            11284..13461
                     /locus_tag="PC592_002265"
     CDS             11284..13461
                     /locus_tag="PC592_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF4056232.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            13458..14459
                     /locus_tag="PC592_002266"
     CDS             13458..14459
                     /locus_tag="PC592_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF4056233.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            14456..15388
                     /locus_tag="PC592_002267"
     CDS             14456..15388
                     /locus_tag="PC592_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4056234.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            15633..15749
                     /locus_tag="PC592_002268"
     CDS             15633..15749
                     /locus_tag="PC592_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDF4056235.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            15765..17684
                     /gene="tet(M)"
                     /locus_tag="PC592_002269"
     CDS             15765..17684
                     /gene="tet(M)"
                     /locus_tag="PC592_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDF4056236.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            17803..17970
                     /locus_tag="PC592_002270"
     CDS             17803..17970
                     /locus_tag="PC592_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDF4056237.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(18030..18383)
                     /locus_tag="PC592_002271"
     CDS             complement(18030..18383)
                     /locus_tag="PC592_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056238.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            18888..19310
                     /locus_tag="PC592_002272"
     CDS             18888..19310
                     /locus_tag="PC592_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4056239.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            19307..19537
                     /locus_tag="PC592_002273"
     CDS             19307..19537
                     /locus_tag="PC592_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056240.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            19998..20201
                     /locus_tag="PC592_002274"
     CDS             19998..20201
                     /locus_tag="PC592_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF4056241.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            20283..21500
                     /locus_tag="PC592_002275"
     CDS             20283..21500
                     /locus_tag="PC592_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4056242.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(21756..22202)
                     /locus_tag="PC592_002276"
                     /pseudo
     CDS             complement(21756..22202)
                     /locus_tag="PC592_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            22247..22726
                     /locus_tag="PC592_002277"
                     /pseudo
     CDS             22247..22726
                     /locus_tag="PC592_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22728..23024
                     /locus_tag="PC592_002278"
     CDS             22728..23024
                     /locus_tag="PC592_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056243.1"
                     /translation="MSEVVKKEVQVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVVATAIMTIVISRRGFPLLYTKTKM"
     gene            23419..24609
                     /locus_tag="PC592_002279"
     CDS             23419..24609
                     /locus_tag="PC592_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF4056244.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQEDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIIQKPVYYPFEAKVKSNNREVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNKSEDWLNELNEYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMGRLKTT
                     FENL"
     misc_binding    24743..24998
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25057..26058
                     /locus_tag="PC592_002280"
     CDS             25057..26058
                     /locus_tag="PC592_002280"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDF4056245.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEDIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            26162..26551
                     /locus_tag="PC592_002281"
     CDS             26162..26551
                     /locus_tag="PC592_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HDF4056246.1"
                     /translation="MDFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIADKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDVIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSTIIENVNFSIKDEEE"
     gene            complement(26716..26862)
                     /locus_tag="PC592_002282"
     CDS             complement(26716..26862)
                     /locus_tag="PC592_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDF4056247.1"
                     /translation="MLLYGTNKKTILDRLGHIDIKIAINKYSHVLEEVKKEISENLSK
                     ILFK"
     gene            27163..27618
                     /locus_tag="PC592_002283"
                     /pseudo
     CDS             27163..27618
                     /locus_tag="PC592_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
     gene            27622..28452
                     /locus_tag="PC592_002284"
     CDS             27622..28452
                     /locus_tag="PC592_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4056248.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVITCPERQFSSKNEEKSHKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRVCDKLGTVFKNRGAKLDKNLYILNSSKPTAVLIESFFCDNKEDYESAKKL
                     GYEGMAKLIVEGILNKGVANNEVKQMYKHTIVYSGDDKVSAEILGLYYKRAKENYLVS
                     DIKDYEPHQTQNLYVIGGETCNKMKEMSNTTGEKFTEIYSDDVWSTMDKAIEFVKEKL
                     "
BASE COUNT         9944 a         4339 c         5626 g         8712 t
ORIGIN      
        1 tcaaaaataa tataatttat agtggagggg aaaatgacta aaattattaa agtacaaaaa
       61 cctaaattta caggagaatt agaaattatt gaaaatcttg aagatatact tgaagatata
      121 tttaatgatg aaaaaatatt taataaaatt atagaaaatg aagttataag tgatttagat
      181 tctgtaagag ttagctttga atcttgtata tttagaaatg tatcctttga aaattgcaat
      241 ttaaaaaaga ttgatttact tgatgttgta tttgaaaact gcaatttatc aaatacattt
      301 tttgatggag gaagtatata tagagttgaa tttaaaaata gtaaattgat aggtgttaga
      361 tttgatgatt gtatacttaa aaacgttttg ttcaaggatg ttttagctaa gtattctaac
      421 ttttcgttct ctaaatttaa gatagtttct attttagatt caaattttga aaattctgta
      481 tttcaagaag taaaaggtga caatctagta tttgagtata caaacttaaa aaaagcaaac
      541 tttaatggaa ctaaactttc tggcatagat tttactacta ataatattga gggaattgag
      601 attggtatag atgatattag aggagcaatt tttgatgtgt cacaagcaat tgatttaacg
      661 aaattgatgg gaattatcat aaaatgaaaa aaatattcat aagataaatt gggaaaacgt
      721 taacaatgtg tgaattttta ccagattgac atttttctga aaataaagta agattatctt
      781 aatattcaaa atattttcaa agggggtaat ttagtgtgag taagcagatg agagatattt
      841 ttatagttgg ttttgcttta ttttctatgt tctttggtgc aggaaatctt atgtttcctc
      901 catttttagg gatggaatcc ggcaaagact ggttaattcc tcttattgga tttgttgttg
      961 cagatgctgg tatagcaatg cttgttatta tagcaacagc aagatgtaag ggaagcatgg
     1021 atgatgtact taggagagct ggtaaagggt tagcaagagt aatgagtgta gctgctctag
     1081 catgtttagc acttcttgta ataccaagaa cttgcgcaac aacatatgaa atgggtatta
     1141 tgcctatatt tggagaccat ggaccagtag ctaaagctat attttcaata attttctttg
     1201 ggttaacttt agcatttact attaggtctt ctaaggttat agacataata ggtaagtatt
     1261 taactccagc gttattatta gtattatttg ttttaatagt aaagggtata atttctccag
     1321 caggacctat gagtcctgaa catatgatag ataaaaatct atttggtgaa ggtatatcac
     1381 aaggttatca aacaatggac gctctaggtg cagcatctat ggcaactata atgttgatgt
     1441 ctataatagc taaaggatat acatcagata aagaccaaat aggaatgact attaaagctg
     1501 gttttgtagc ctgtgtattt ctagcagtag tatatggtgg tcttacttat ttaggtgcaa
     1561 cagtttcaac tttatatgac actagtatac ctcaagcatc tttattagtt gaaataacta
     1621 gtatattgtt atatggtcaa gtaggaaagg taattttagg tgtaattgtg gcacttgcct
     1681 gtctgactac ttctacaggt ttaacagcat caatatcaac ttattttgaa ggaataagta
     1741 aggcgagtta taaacaactg gttataggta tatgtgtagc tagtatgctt atatcaaatt
     1801 taggtgttga ttctataata gccatatcag ttccaatcct acaaactata tatcctgttt
     1861 tattagcaat agttgttatg gagttggctg gtaaacatat aaagaatgat aatgctttta
     1921 aaggtgcagc atatgttaca ttagtgatta gtttattatc agctataaat ggaatgacag
     1981 gagctgttcc atttatacaa agcttaccac ttgcaggttt gggctttaac tgggtaatac
     2041 cagctatatt gggtggaata gttggtaact ttataaaaag caacaaacaa gtagcataat
     2101 aatttgtaat taatttaatt ttataatata ttaattttta gtactatggg taggtttaat
     2161 ttaaacctaa tctacccata gtacttttta gattggatta gaatagcatg tatataattt
     2221 tttataatat aatttttctt tgaagtatga taaaattagt aatagtgata agaaagtaca
     2281 aatttaggag gttttaatta atgcttagaa aaataacagc atttatgcta tctatatgtt
     2341 taattattgg acttacaggt tgtagtttac ttgtgggcaa gaaagataaa gagaaagtta
     2401 tagatgattt taaagttgca gtggtaactc aaccattatc tgaaaataaa gtacaataca
     2461 atatggtgga agagatggca aaagaatatg aggaagagaa taagattgat aaagacaaag
     2521 atggtcaaac taaagttaaa caaactataa agcatgttgt acttccagaa aattttactt
     2581 ctaatataga tagtgctatt aataagatag taaagttggc tgacgataaa gaagttcagg
     2641 ctattgtagt ttcaactgac caagcggggc ttttacctgc cttacaaaag gtaaaggaaa
     2701 agcgtccaga aataataact atttctgccc ctatgggaga tgataaaaat caattaagcc
     2761 aatttgttga tgtgaatcta ggggttagtg cagaggaaag aggaaaagta ttagctgaac
     2821 gttcaaaaga aatgggagca aaagctttta ttcattatgc ctctacagat gatttgaaag
     2881 atgttaatat agccaaaaga ttagaaatga ttaaagagac ttgcaaaaat ataggattgc
     2941 catttgtaca agttaatact ccaaatataa atgctgaaga agacaaaaac aaagttaagc
     3001 agtttttaaa tgaagatatt gaaaaacaag ttaaaaaata tggaaaagat ataaatgtat
     3061 ttggtgtaaa tgattatatg gatgaagtta tattgactaa ggctttagaa ttaaagtata
     3121 tagttgcaga gcaaagtaat ccatcaccaa tacaaacata tcctagtgtt atgggtctga
     3181 aaatatctaa aaaagatgct caaaattatg ataaaataaa cgacatgata agtgaaaagg
     3241 ctaaggcttt tggtatgtca aatagacttg gtggatatcc tatgccaatg gatgcttttc
     3301 taccatcatt agcaatttat cttgccactg aaatggtaaa acaagattta acacaagaag
     3361 atgtatgtga cccagactat ttagaggcgt ttacagaatt aagatttggg ataggttcag
     3421 aatttacacc tctaacagag gtactttata attatcaatc agtaatttta agccaattaa
     3481 tttattaata ttaaggaagt gtctcaaaat gaacttttta gtttatgagg cactcttttt
     3541 gtattaaata aaatatattt ttatcttttt aacaattaaa aagaagctta tctctatgtt
     3601 gagatagcct cgtttttaac ataaataagt tttattaata taaaaatagc ataaaaatct
     3661 agttatccgc ataaaaactg gacttatcac actttatcaa ggtcaaaacc actcaattta
     3721 ctactaattt actacttatg aatgagcttt gatacgacga tttatccttg aaaagtgaag
     3781 atataaagat acttccaata aaatttgaat atttaatagg tagacacttc aaaaaatgag
     3841 gtgtctattt ttttacccga ttttgaaagg aagtgaactt atgaaaacaa aaaatcaaga
     3901 atcaaaaggt cgttccccac tctttaagac catcaaacat tcattcagcc aataaaaaag
     3961 aaaggatagg taaaaatatg gaacttaaat ttgtgattcc caacatggaa aaaacattcg
     4021 gcaatttaga atttgctggc gaggataaag tcgttcagcg aagaatcaac ggacggctaa
     4081 ctgtcttatc aagaagctat aatctctatt ctgatgttca aagagcagat gatattgtgg
     4141 tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt tgaggaacgt gtgaagttag
     4201 tcaatccacg tattaccgca gagggctaca aaatcggcac tcgtggtttt acaaattacc
     4261 ttttacatgc tgacgacatg ataaaagaat aaagaaagag aggaaaaatg atgagattag
     4321 caaatggcat tgtattagat aaagacacga cttttggaga attgaaattc tctgctctac
     4381 gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc agatgaaatc aaggaacgta
     4441 cctatgactt aaaatccaaa ggacaaggac gcatgattca agtaagtatt cctgccagcg
     4501 tgcctttgaa agagtttgat tataacgcac gggtggaact tatcaatccc attgcggaca
     4561 ccgttgctac tgccacctat caaggagcag atgttgactg gtatatcaag gcagacgata
     4621 ttgtgctgac aaaggattct agttcattca aagctcaacc acaagcaaag aaagaaccga
     4681 cacaagacaa atagtcgcta ggtagaaagg agactttttc gcatgaaaca gcgtggtaaa
     4741 aggattcgcc catctggtaa agatttagtc tttcatttta cgatagcgtc actcctgcct
     4801 gttttcctgc tggttgtcgg actgtttcat gtgaagacaa tccagcagat caactggcag
     4861 gattttaacc tatcacaagc agataagatt gacattccct atttaattat cagtttcagt
     4921 gtcgcaattc ttatctgctt gctggtagcg tttgtattca aacgggttcg ctatgatacg
     4981 gttaaacaac tttaccaccg tcaaaaactg gcaaagatga tacttgaaaa caagtggtat
     5041 gaatctgaac aggtcaaaac agagggtttc tttaaagata gtgctggtcg tacaaaggaa
     5101 aagataacct acttccctaa aatgtattat cgacttaaaa atggcttgat acagatacgg
     5161 gtggaaatca cgctgggaaa atatcaagac caactcttac acttggaaaa gaaattagag
     5221 agtggcttgt actgtgagct gacggataaa gagttaaagg attcctatgt ggaatatact
     5281 ttgctctatg acaccatagc cagtcgtatt tctattgatg aagtagaagc taaagatggt
     5341 aaacttcgct taatgaaaaa cgtatggtgg gaatatgata agctccctca tatgttgatt
     5401 gctggtggta caggtggcgg taaaacttac tttatactga cactgattga agccttgctt
     5461 catacagatt caaaactgta tattcttgac ccgaaaaatg ctgatcttgc ggacttaggt
     5521 tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc tttcttgcat tgaaacattc
     5581 tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga tgaagaacta taagactggc
     5641 aaaaattatg cttacttagg tctcccggca cacttcttaa tctttgatga atacgtcgct
     5701 ttcatggaaa tgctgggaac aaaagaaaac accgcagtta tgaataagct gaaacagatt
     5761 gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg cttgtcaacg tccagacgca
     5821 aaatatttag gcgacggaat ccgtgatcag tttaatttca gagtggcttt aggtcgtatg
     5881 tctgaaatgg gctatggcat gatgtttggc agtgacgtac aaaaggattt cttcttaaag
     5941 cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg tcatatcaga gttttatact
     6001 ccccttgtac caaaaggata tgatttcttg gaggaaatta aaaagttatc caacagcaga
     6061 cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg tggactgatc ttgctggctg
     6121 gtgtggcaat agccacgcca gcacttaacc ccccgtatct aacagggggg tacaaatcga
     6181 caggaaacag tcaaaaaaac attagaaaat cctttggtta caagggattt acaaaatttc
     6241 agcgtatgtc aaatgggctt taaaagttga catacgcctt tttgattgga gggattttta
     6301 ctgaatgaac aaacttggtt acagcattta aaagaaaaac gcttggctta tggactatct
     6361 caaaaccgtt tagctgttgc gactggtatt acaaggcagt atctaagcga tattgaaaca
     6421 ggaaaagtca agccatcaga ggatttacag cagtcccttt gggaagctct ggaacgcttc
     6481 aatcccgacg ctccccttga aatgctgttt gattatgtaa gaattcgctt tccgacaaca
     6541 gacgtacagc aggtggtcga aaacatctta caactgaaac tgtcctattt tcttcatgag
     6601 gactatggtt tctattctta ttcagagcat tatgctttag gcgacatatt cgtcctttgc
     6661 tcccatgaac tggacaaagg agttctggtg gaattgaaag gtcgtgggtg cagacaattt
     6721 gaaagctatc ttctggcaca acaaagaagc tggtatgagt tctttatgga cgttttggtg
     6781 gctggcggtg tgatgaaacg ccttgacctt gccattaacg ataagacagg gattttaaat
     6841 atccctgtac tcactgaaaa gtgccaacag gaagaatgta tctccgtctt ccgcagtttt
     6901 aaaagctatc gcagtggcga actggtacgc aaagaggaaa aggaatgtat gggaaacacc
     6961 ctctatatcg gttcattaca aagtgaagtt tatttctgta tctatgaaaa ggactacgag
     7021 cagtacaaga aaaatgatat tcccattgaa gacgcagaag taaaaaaccg ttttgagatt
     7081 cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt tactcgtcta tgacaatcca
     7141 gagcataccg cctttaaaat tatcaatcgg tatatccgtt ttgtagataa agacgattcc
     7201 aaacctcgtt ctgattggaa actgaatgaa gaatgggctt ggtttattgg gaacaatcgt
     7261 gaacgattaa aactaaccac aaaaccagag ccttactcct tccaaaggac gctgaactgg
     7321 ctatctcatc aagttgcccc gaccttaaag gttgcgatta aacttgatga aatcaaccag
     7381 acgcaggttg taaaagacat tctcgaccat gcgaaactga cagaccgaca caagcagatt
     7441 ttgaagcaac agtcagtaaa agaacaggac gtgataacaa caaaaaaata actcaaatac
     7501 aaattcattg aatatagaga ggagaacatt tttatgaatt ttggacaaaa cctttataac
     7561 tggtttctat caaacgctca atcactggtg cttttagcaa tcgttgtgat tggcttgtat
     7621 cttggcttca agcgtgagtt tagcaaactg attggctttt taattattgc gattattgcg
     7681 gttggcttag tcttcaacgc tgctggagta aaagacattt tactagagct attcaatcgc
     7741 attattggtg cttaaataaa accgttcttt tgtggaatat aagtggtttt cttatgttcc
     7801 gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt ttgaatctct acaaagaaag
     7861 gacgtgaata tatggacgat atgcaagtct atattgcgaa tttaggcaaa tacaatgagg
     7921 gcgaattggt cggtgcgtgg tttacctttc ccattgactt tgaggaagtc aaagagaaaa
     7981 tcggcttgaa tgatgaatat gaggaatacg ccattcatga ctacgagtta ccctttacgg
     8041 ttgacgaata cacttccatt ggcgaactca atcgactatg ggaaatggta tcggaattac
     8101 ccgaagaatt acaatcggag ctatctgctc tgctcactca tttttcaagc attgaagaac
     8161 taagcgaaca tcaagaggat attatcattc attccgattg tgatgatatg tatgacgtgg
     8221 cacgctacta cattgaagaa acgggtgctt taggcgaagt accagctagt cttcaaaact
     8281 atattgatta tcaagcctat ggtcgggatt tagacctttc aggaacgttt atctcaacca
     8341 atcatgggat ttttgaaatc gtctattaaa tctgtcggta cattactact ggcagatttt
     8401 ctattttacg gggtggctca atcagctacc cctatttttt atgaaaggat tgattacatg
     8461 aagaaaatac gaagctatac cagtatctgg tctgtggaaa aggtactgta ttctatcaat
     8521 gattttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     8581 tttgcagtga tgatacttgg caacttgccc cctctttcca tgatagaggg agcatttctc
     8641 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ttttgatggt
     8701 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacc aaagctgacc
     8761 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     8821 aggagtgaat tttatggcat atccaattaa atacattgaa aacaatctcg tctggaataa
     8881 agacggggaa tgttatgctt actatgagct tgttccttac aattactcat ttctaagtcc
     8941 agaacagaaa atacaagtgc atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     9001 caaaattcat gctttacaaa tcagtacaga atccagcata cgttctgcac aagagcgttc
     9061 caaaaatgaa gtcactggca agctcaaagc ggttgcctat gacaaaatcg accaacagac
     9121 agacgcttta atatccatga ttggcgaaaa tcaagtgaac taccgtttct ttatcggctt
     9181 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     9241 tgctttgtct gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     9301 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag ctcttagaaa ataaaatctc
     9361 tcgtcgtttc aaaatccgca ggttagataa ggacgacttc ggctatctga ttgaacacct
     9421 ttacggacag acaggcactg cctatgaaga gtatgagtac catctatcaa agaaaaagct
     9481 ggataatgaa acgctgatta aatactatga cttgattaag cctactcgct gtttggtgga
     9541 agaaaaacag cgatatttga aaatccagca ggaagatgaa accgtctatg tagcttactt
     9601 taccattaac agcattgtcg gagaactgga cttcccgtcc tctgaaatct tctactacca
     9661 gcaacagcaa tttacattcc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     9721 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     9781 ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa gctctggaaa gtgtgaatga
     9841 gctggaaacc aatttagacc aaagcaagga atctatgtac aagctgtctt atgtggtaag
     9901 ggtatcagca aatgatcttg acgaactcaa acgtcgttgt aatgaagtga aagattttta
     9961 tgacgattta agcgtaaaac tggtacgacc atttggggat atgctcggct tacatgaaga
    10021 atttttacct gccagcaagc gttatatgaa tgattatatt caatacgtga cctctgattt
    10081 cctcgctggt ttaggttttg gtgctactca aatgctgggg gaaaatgagg ggatttatgt
    10141 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
    10201 ggttaagggt tcagtaacca atgcgttagc gtcggctttt gttggttcgc tgggtggtgg
    10261 taaatccttt gcgaataacc ttatcgtcta ttatgcggtg ctttatgggg cacaagcagt
    10321 gattgtagac ccaaaagcag aacgtggcag atggaaagaa accttgccag agatttccca
    10381 tgaaatcaat atcgtcactc tgacttctga tgagaaaaac aaaggcttac ttgaccctta
    10441 tgtgattatg aaaaatccca aagattctga atcactggct attgatattc tgacattcct
    10501 tacggggatt tcctctcgtg atggggaacg cttcccaatc cttagaaaag ccattcgtgc
    10561 agtaaccaat agtgaagtac gagggttgat gaaagtgatt gaggaattac gggttgagaa
    10621 tacgccacta agtaccagta tagccgacca tatcgaaagt tttacagact atgactttgc
    10681 acatttatta ttcagtaatg gttatgtgga gcagtctatc agcttagaaa aacaactgaa
    10741 cattatacag gttgcggact tggtacttcc cgacaaggaa acttcctttg aggaatatac
    10801 cactatggag cttttatccg ttgctatgct gattgtcatt agtacctttg ctttagactt
    10861 tatccataca gaccgaagca ttttcaagat tgtagattta gacgaagcat ggagcttttt
    10921 acaggtagca caaggaaaaa cactatctat gaagctggtt cgggctggtc gtgctatgaa
    10981 cgctggggta tatttcgtga cccaaaatac agacgacctc ttagatgaaa aactgaaaaa
    11041 taacctcggc ttaaaatttg catttcgttc cactgacctt aacgagatta aaaagacctt
    11101 agcctttttt ggtgtagacc cagaggacga aaacaatcag aagcgattgc gtgatttgga
    11161 aaacgggcaa tgccttatca gtgatttata tggtcgtgtc ggtgtgatac agttccaccc
    11221 tgtatttgaa gaactgctcc atgcctttga taccagacca cctgtgcgaa aagaggtgta
    11281 aatgtgaaac catcaatagt aaacagaata aaatcaaact ggacgctgaa acgtctaggt
    11341 aaagtggcaa tgacagtggc tttcacactt gtgattgcca tttttctttt agccatgctg
    11401 ggaacggtgg ttcaagctgc gggcttggta gatgatacgg tcaatgtggc aaatgaatac
    11461 agccgatacc cacttgaaaa ctatcaactg gatttttatg tggataatag ctggggctgg
    11521 cttccgtgga actggtcgga cgggattgga aaacaggtca tgtatggact atatgccatt
    11581 accaatttta tttggacaat cagtttgtat gtttccaatg cgacaggtta cttagtacag
    11641 gaagcctatt ccttagactt catttccgct acagcagatt ccattggtaa gaatatgcag
    11701 accttagctg gtgtgagtgc aaacggattt tcaacagagg gtttctatgt tggattcctc
    11761 ttactcttga ttttggttct tggggtttat gttgcctata cgggactgat aaagagagaa
    11821 accacaaagg caattcatgc cattatgaat tttgtgctgg tgtttatcct atcggcttcc
    11881 tttattgcct acgctcccga ctacattaaa aaaatcaatg acttttcatc agacatcagt
    11941 aatgccagtt tatcacttgg cacgaagatt gtcatgcccc attccgatag tcaaggcaag
    12001 gacagcgtgg acttaatcag agatagcctg ttttccatac aggttcagca accgtggcta
    12061 ctgcttcaat acaacagttc agacattgaa agtatcggta ttgaccgtgt ggaaagcctg
    12121 ctctccacca gcccagattc caacaatggc gaagacagag aaaaaattgt tgcggaagaa
    12181 attgaagaca gaagcaatac caatctaacc attacaaaga ccattaaccg tttaggtaca
    12241 gtcttcttcc tatttgtctt caatattggg atttccatat ttgtattcct attaacagga
    12301 atcatgattt tctcgcaggt actttttatc atctatgcta tgtttctgcc tgtgagcttt
    12361 attttaagca tgattccatc atttgatggt atgtcaaaac gagccataac aaagctcttt
    12421 aataccattt tgacacgagc tggaatcaca ttgattatta cgacagcatt tagtatttca
    12481 accatgctct ataccttatc ggctggttat ccgttctttt tgattgcttt tctacagatt
    12541 gtgacctttg caggaatcta cttcaagctg ggcgatttaa tgagtatgtt ttctctacag
    12601 agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa aacctcgtat gcttatgcac
    12661 gctcacatgc accgtctaca gcggaaactt ggacgttcca tgactactct aggggctggg
    12721 tctgccattg ttacaggtaa aaaaggacag tcgggttcgg ggagttctgc aaggacacaa
    12781 gcagatcact cccgaccaga cggaaaggaa aaatcaacac ttggaaaacg tatcggtcaa
    12841 accatcggta cagtagctga taccaaagac agaatggtag acactgctag tggtttgaaa
    12901 gaacaggtta aagatttgcc gaccaatgca agatatgcag tatatcaagg aaaatccaaa
    12961 gtaaaagaga atgtccgtga tttaaccagt agtatttctc aaaccaaagc ggacagagcc
    13021 agtggacgca aggaacagca ggaacaaagg cgaaaaacca ttgcgaagcg tcgctctgaa
    13081 atggaacagg tcaaacagaa aaaacagcct gcttcttctg ttcatgaaag accgactaca
    13141 agacaagaac aatatcatga tgaacagacc tcaaaacagt ctaatattca gacttcatat
    13201 aaggaatctc aacaagccaa acaagagcgt ccagcagtta agtccgattt ttcaagtcca
    13261 aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg ttcaaaagcc agcaacttca
    13321 accactacag cagatagaac ttcacaacgt ccaatcacaa aagaacgtcc gtctactgtt
    13381 caaagagtac cactacaaaa tacaagaagt agaccaccaa tcaaaaccgc caccattaag
    13441 aaagtcggta agaaaccatg aagttgaaaa ctttagtgat tggtggttct ggattattct
    13501 tgatggtctt ctcactgctt ctgtttgttg ccattttatt ttcagatgaa caggacagcg
    13561 gaatttccaa tattcattat ggaggtgtga atgtttccgc agaagtgctg gctcataagc
    13621 ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga atatgtcaac atacttcttg
    13681 cgattataca ggtggaatcg ggcggtactg cggaagatgt tatgcagtcc tcggaatccc
    13741 tcggtcttcc acctaattca ttgagtacag aagaatccat taagcaaggt gtgaagtatt
    13801 tcagtgaatt attagccagt agcgaaaggc tcagtgtaga tttagaatcg gttatccagt
    13861 cctacaatta tggtggtggt ttcttagggt atgtggctaa tcgtggaaat aaatatacct
    13921 ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg cgaaaaagtg tcttacccca
    13981 atcccatagc catacctatc aatgggggct ggcgatacaa ctatggcaat atgttttatg
    14041 tgcaactggt aacgcagtat cttgtcacaa cagagtttga tgatgatacg gtacaagcca
    14101 tcatggacga agcactgaaa tatgagggct ggcgatacgt ttacggtgga gcttccccga
    14161 ctacttcttt tgattgtagc ggactgacac aatggacgta tggaaaagct ggaattaact
    14221 taccacgaac cgcacaacag caatatgatg tgacccagca tatcccacta tcggaagcac
    14281 aagctggcga tttggttttc tttcattcta cctataacgc tggctcttat attactcatg
    14341 ttgggatata ccttggcaat aaccgtatgt ttcatgcagg cgacccaatc ggttatgccg
    14401 acttaacaag cccctactgg caacagcatt tagtgggagc aggacgaatc aaacaatgag
    14461 aaaggaagat ttaatgatga aatttagaaa aaatcagaat aaagaaaaac agataccaaa
    14521 ggaaaagaaa cctcgtgtct ataaggtcaa tcctcataaa aaggttgtga ttgccttgtg
    14581 ggtactttta gggcttagtt tcagctttgc gatattcaag cactttacag ctatagatac
    14641 tcatactatt cacgaaacaa ctatcataga aaaggaatac gttgatactc atcatgtaga
    14701 aaattttgta gagaactttg cgaaagtcta ctattcatgg gagcaatccg ataagtccat
    14761 tgataatcga atggaaagtc taaaaggcta tctgacagat gaacttcaag ctctcaatgt
    14821 tgatacagta cgcaaagata ttcctgtatc gtcttctgta agaggatttc agatatggac
    14881 ggtagagcca actggcgaca atgagtttaa tgtaacctac agtgtagacc agctcattac
    14941 agagggagaa aatacaaaga ccgtccactc tgcttatata gtgagtgtct atgtagatgg
    15001 ttctggaaat atggtactgg ttaagaatcc gaccattacc aacataccta agaaatcaag
    15061 ttataaacca aaagccattg aaagtgaggg gacggttgat tccattacaa ccaatgaaat
    15121 caatgagttt ttaacgacgt tcttcaagct ctatcctaca gcgacagcca gtgaactttc
    15181 ctactatgtg aatgacggga tattaaaacc aatcggaaaa gagtacatct ttcaagaact
    15241 ggtaaatcct attcacaatc gtaaggataa tcaagtcacg gtatcgctga cagtggagta
    15301 tatcgaccag cagaccaaag caacgcaggt atctcaattt gatttggtac ttgaaaagaa
    15361 cgggagtaat tggaagattg taaaataaca aatattggta catgattaca gatactttgt
    15421 aatcatgtac tctttttgat aaaaaattgg agattccttt acaaatatgc tcttacgtgc
    15481 tattatttaa gtgactattt aaaaggagtt aataaatatg cggcaaggta ttcttaaata
    15541 aactgtcaat ttgatagcgg gaacaaataa ttagatgtcc ttttttagga gggcttagtt
    15601 ttttgtaccc agtttaagaa tacctttatc atgtgattct aaagtatcca gagaatatct
    15661 gtatgctttg tatacctatg gttatgcata aaaatcccag tgataaaagt atttatcact
    15721 gggattttta tgcccttttg ggtttttgaa tggaggaaaa tcaaatgaaa attattaata
    15781 ttggagtttt agctcatgtt gatgcaggaa aaactacctt aacagaaagc ttattatata
    15841 acagtggagc gattacagaa ttaggaagcg tggacaaagg tacaacgagg acggataata
    15901 cgcttttaga acgtcagaga ggaattacaa ttcagacagg aataacctct tttcagtggg
    15961 aaaatacgaa ggtgaacatc atagacacgc caggacatat ggatttctta gcagaagtat
    16021 atcgttcatt atcagtttta gatggggcaa ttctactgat ttctgcaaaa gatggcgtac
    16081 aagcacaaac tcgtatatta tttcatgcac ttaggaaaat ggggattccc acaatctttt
    16141 ttatcaataa gattgaccaa aatggaattg atttatcaac ggtttatcag gatattaaag
    16201 agaaactttc tgccgaaatt gtaatcaaac agaaggtaga actgtatcct aatatgtgtg
    16261 tgacgaactt taccgaatct gaacaatggg atacggtaat agagggaaac gatgaccttt
    16321 tagagaaata tatgtccggt aaatcattag aagcattgga actcgaacaa gaggaaagca
    16381 taagatttca taattgttcc ctgttccctg tttatcacgg aagtgcaaaa aacaatatag
    16441 ggattgataa ccttatagaa gtgattacga ataaatttta ttcatcaaca catcgaggtc
    16501 cgtctgaact ttgcggaaat gttttcaaaa ttgaatatac aaaaaaaaga caacgtcttg
    16561 catatatacg cctttatagt ggagtactac atttacgaga ttcggttaga gtatcagaaa
    16621 aagaaaaaat aaaagttaca gaaatgtata cttcaataaa tggtgaatta tgtaagattg
    16681 atagagctta ttctggagaa attgttattt tgcaaaatga gtttttgaag ttaaatagtg
    16741 ttcttggaga tacaaaacta ttgccacaga gaaaaaagat tgaaaatccg caccctctac
    16801 tacaaacaac tgttgaaccg agtaaacctg aacagagaga aatgttgctt gatgcccttt
    16861 tggaaatctc agatagtgat ccgcttctac gatattacgt ggattctacg acacatgaaa
    16921 ttatactttc tttcttaggg aaagtacaaa tggaagtgat tagtgcactg ttgcaagaaa
    16981 agtatcatgt ggagatagaa ctaaaagagc ctacagtcat ttatatggag agaccgttaa
    17041 aaaatgcaga atataccatt cacatcgaag tgccgccaaa tcctttctgg gcttccattg
    17101 gtttatctgt atcaccgctt ccgttgggaa gtggaatgca gtatgagagc tcggtttctc
    17161 ttggatactt aaatcaatca tttcaaaatg cagttatgga agggatacgc tatggttgcg
    17221 aacaaggatt atatggttgg aatgtgacgg attgtaaaat ctgttttaag tatggcttat
    17281 actatagccc tgttagtacc ccagcagatt ttcggatgct tgctcctatt gtattggaac
    17341 aagtcttaaa aaaagctgga acagaattgt tagagccata tcttagtttt aaaatttatg
    17401 cgccacagga atatctttca cgagcataca acgatgctcc taaatattgt gcgaacatcg
    17461 tagacactca attgaaaaat aatgaggtca ttcttagtgg agaaatccct gctcggtgta
    17521 ttcaagaata tcgtagtgat ttaactttct ttacaaatgg acgtagtgtt tgtttaacag
    17581 agttaaaagg gtaccatgtt actaccggtg aacctgtttg ccagccccgt cgtccaaata
    17641 gtcggataga taaagtacga tatatgttca ataaaataac ttagtgtatt ttatgttgtt
    17701 atataaatat ggtttcttgt taaataagat gaaatatttt ttaataaaga tttgaattaa
    17761 agtgtaaagg aggagatagt tattataaac tacaagtgga tattgtgtcc tgtatgtgga
    17821 aataaaacac gattaaagat aagggaagat actgaattaa aaaaattccc cctctattgt
    17881 ccgaaatgca gacaagaaaa tttaattgaa ataaagcagt tcaaagtaac tgtgattaca
    17941 gagccagacg caaagacgca gagccgataa aatgagatta atacaatctc attttatcgg
    18001 ctctttccgt tatgtatgga ttcttttaat tagtcttcga tgtttcttgc ttcgttgata
    18061 ccgctggcta aagattccat taaggatagt tctttgtctg taaagctatc catgtatttc
    18121 tctatctgta atcgtcgggt gctttttacc aagttattag caggtaagaa aaattcatca
    18181 acggaaacat gaagtaacga tacaaggtca taaagaactt gtatgctggg gtgttgccct
    18241 ttattttcaa tattagttaa gtaccgtggg tcaatttcaa tcaatgctcc cacttgttca
    18301 cgagttaaac ctcgtttcaa tcgagcttct ttaatggcta aaccaaaggc tctaaaatca
    18361 tatttatctt cttttttacg catagtagac cacctctata cattttattg ttcctactga
    18421 attaaaaaca ggtatagaaa aacgtgttat atggtttata ggtttatatt taataaaaag
    18481 cactactaaa cgccaataaa aaaaaccgtt atatggtagt gctatttacg ctgttaaaat
    18541 attgtatatt acttccaaat ggcggtttgt tggaggtcaa cgtcgccatg aagtacatca
    18601 tatacaataa atttccttac attgggttct tgtcaaaaaa agtcgtctat ctgcaataga
    18661 taagtacgtc caccaatgtg gttttataaa tcatatagat agaataacag aagcatgtaa
    18721 acagagaaat aaatctgttt atatgctttt ttggctattc agaacttttt tacaaagttt
    18781 atttatcagt aatgcaacaa atcccccttt cacattggga ctaagagtga aaggagataa
    18841 acgagcaagg ctcacttcct ttcctagaca gaaagggggt gagaaacatg aaaccatctt
    18901 cttttcagac cacaatagaa aatcagtttg actatatctg taaacgtgct atggaagacg
    18961 agcgaaagaa ttatatgctt tatctttcaa ggattgcaaa gcgtgaggtg tccttttcgg
    19021 atgttggcga ttatcttgtt agccagtttg cgacaacaga taactattca actgactttc
    19081 agatttttac actcaatggg ttatcagtag gcgttgaaaa tgatttgttg agtgaagcat
    19141 tacgtgagtt gccagacaag aaacgtgaaa ttctactgct gttttacttt atggacatga
    19201 gcgattcaga aattgcagac ctgttgaaat tgaaccgttc tactgtctat cggcatagaa
    19261 ccagtggact agccttaatt aaaaagttta tggaggaatt tgaagaatga aaacacaata
    19321 tcctatgatt ccctttcctc tcattgtaaa ggcaacagat ggcgataccg aagcgattaa
    19381 ccagattcta catcattaca gagggtacat aacgaagcgt tccctacgac ttatgaaaga
    19441 tgaatatggc aatcaaagta tggtcgttga tgaagtctta cgtggaagaa tggaaaccag
    19501 actgattaca aagattttgt catttgaaat taagtaatat cctctctcct ttcgtggaag
    19561 cgtgctaaac cattccacgc ttcccgaaca gggaggtttg ttattccacc aaagcatatt
    19621 gagctttcaa tgtgttttga taggctaacg agccattgtt ctttgaaaac tgaataaaag
    19681 taatcgaata cgtttcgata agaaaagagc caacggaact aaccgccatg acctatctta
    19741 taaagatagc gagcgattca tgttagtgat ccgagaagca atctttagca ggattgcctg
    19801 caacgacatt cttatcgtga taatgatact cccatacagt caatagtccg agcgtgataa
    19861 aaccgtcgca ggcaatgagt atggctacat gagaaccatg caggggtgga actcccgtga
    19921 gctttgctaa agctgttcga ttgctggtaa aacaactttt atgaaatcca aataagtgat
    19981 ttggaaagga ggattttatg aagcagactg acattcctat ttgggaacgt tataccctaa
    20041 ccattgaaga agcgtcaaaa tattttcgta ttggcgaaaa caagctacga cgcttggcag
    20101 aggaaaataa aaatgcaaat tggctgatta tgaatggcaa tcgtattcag attaaacgaa
    20161 aacaatttga aaaaattata gatacattgg acgcaatcta gcgtcgccaa agggtcttgt
    20221 atatgataaa atagtattaa gtcgtatcaa ggctctttcc ataaaggaaa ggagcaaatg
    20281 ccatgtcaga aaaaagacgt gacaataaag gtcgaatctt aaagactgga gagagccaac
    20341 gaaaagacgg aagatactta tacaaatata tagattcatt tggagaaccg caatttgttt
    20401 actcgtggaa acttgtggct acagaccgag taccagcagg aaagcgtgat tgtatctcac
    20461 ttagagagaa aatcgcagag ttacagaaag acattcatga tggtattgat gttgtaggaa
    20521 agaaaatgac actctgccag ctttacgcaa aacagaacgc tcaaagacca aaggttagaa
    20581 aaaacactga aactggacgc aaatatctta tggatatttt gaagaaagac aagttaggtg
    20641 taagaagtat tgacagtatt aagccatcag acgctaaaga atgggctatt agaatgagtg
    20701 aaaatggtta tgcttatcaa accatcaata actacaaacg ttctttaaag gcttcattct
    20761 atattgctat acaagatgat tgtgttcgga agaatccatt tgactttcaa ctgaaagcag
    20821 ttcttgatga tgatactgtc cctaagaccg tactaacaga agaacaggaa gaaaaactgt
    20881 tagcctttgc aaaagctgat aaaacctaca gcaaaaatta tgatgaaatt ctgatactct
    20941 taaaaacagg tcttcgtatt tcagagtttg gtggtttgac acttccagat ttagattttg
    21001 agaatcgtct tgtcaatata gaccatcagc tattgagaga tactgaaatt gggtactaca
    21061 ttgaaacacc aaagaccaaa agtggcgaac gtcaagttcc tatggttgaa gaagcctatc
    21121 aagcatttaa gcgagtgtta gcgaatcgaa agaatgataa gcgtgttgag attgatggat
    21181 atagtgattt cctctttctt aatagaaaga actatccaaa agtggcaagt gattacaacg
    21241 gcatgatgaa aggtcttgtt aagaaataca ataagtataa cgaggataaa ttgccacaca
    21301 tcactccaca tagtttgcga catacattct gtaccaacta tgcaaatgca ggaatgaatc
    21361 caaaggcatt acagtacatt atgggacatg ctaatatagc catgacgctg aactattacg
    21421 cacatgcaac attcgattct gcaatggcag aaatgaaacg cttgaataaa gagaagcaac
    21481 aggagcgtct tgttgcttag tagtacaaat gaatttacta cttatttacc acttctgaca
    21541 gctaagacat gaggaaatat gcaaagaaac gtgaagtatc ttcctacagt aaaaatactc
    21601 gaaagcacat agaataaggc tttacgagca tttaagaaaa tataaaaaga taattagaaa
    21661 tttatacttt gtttatttta taaaaaattt atagaaaaat aaaaaattat aattatatat
    21721 aaattttgat aaagtaaaga tgaattacta taggtttaaa ttatattatt ttttattatt
    21781 tttatgcctt tctcagttat tgatgagcct tttcttcctt tactagaaat taagtatcca
    21841 ttgcgtgtca aatattctag catatttctt acttcgtatt ctgtgacatt atattccata
    21901 aatttcatta actttgtcct ccccattggt ttcatgtgca atgattttag gatagaaatg
    21961 catatgtttt tgtcatattg gcttaaatca ttgaatatgg acatattact tgacatatga
    22021 ttattattta attttgaaga tatgttttga ggtaaatcat ttattgtaag ataattagag
    22081 cccatgtaag ccatatattc aacacaattt ctcagttctc taatatttcc catccaagtg
    22141 tatgaattta aagcttctaa aagactctta tcgagtttta tgtttttata gggaagttct
    22201 ttctaagtaa agacttattt acaaaagtaa ctttgttaaa agtattatag ctgcaaactt
    22261 tagagacgat ggaggtactg gttctagaga aggatggtta tatgcattga cactaatacc
    22321 atcagttatg tttgcacttg gagtagttag agttatagac cacttagatg gaatgaaggc
    22381 agctcaaaag cttcttagtc cactattaaa gccattatta gggttacctg gatttgcagg
    22441 gctaaccttg atagctagtt tacagtctac agatgcagct gcatctatga ctaaagaact
    22501 taaagatgat ggatatatag atgaaaaaca aaaagctgta ttctgtgcat ttcaattttc
    22561 aggcgcctct gcaattacaa atttctttgc ttctggagca gcactatttc catttatagg
    22621 ggatgtacca atatttatac cacttacttt aatattaatt atgaagtttg ttggggcaaa
    22681 cttacttaga ttatatttaa ataaatttga caagggggaa gcttaacatg agtgaggtag
    22741 taaaaaaaga agtacaagtt aaaaaaggaa atgtgataga tgcgtttatt ggaggagcta
    22801 gaaatggatt ccaaataagt accaattcaa tggctccaaa tgtcatcttc ggttttgcta
    22861 taatttctgt attcaattta acaggtcttt tagatgtaat agggactata tttacacctg
    22921 taatgagtat atttggactt ccaggtgttg tagcaacagc tataatgaca atagttatat
    22981 cgcggagagg attcccatta ttatacacaa aaactaaaat gtaaaactac atatattgga
    23041 ttaggagctg atgctacacc agggtttcat aatccaaatg taacatttga tacgaaagct
    23101 ttagaatatg gtgtagattg gttgaaaaga gattgggata atatccaaat taataattct
    23161 acatttaaaa ttataattat agaagttata gaaaaagatt gcttatgtta attgaaaaat
    23221 aattaatatg ggcaatctta ttttgctata atgaaactta ttttgaaata ttgaaaaaat
    23281 atggtagaaa aagcaattat attttaagtc tattgggcaa aaaagtgata ttataatatt
    23341 aaggattata aaatgatatc aaattgaatc tagtaataca ctaacaatta taaaaatttt
    23401 atttttagga gggaaaaaat gagtaagtat aactttgaca gagtaataga tagagtagga
    23461 acagattgtg taaagtggga ttttagaact aattgctcaa ctaaagcaca agaagatggt
    23521 ttgccttttt ggattgcaga tatggatttt gaatgtgcag aaccaataat agaagcatta
    23581 cgtaaaaaag ttgaacataa aatatttgga tatagttcca atgatagtga taaatacttt
    23641 aatgcagttt gtgattggta taaaaggaga tttaactggg aaataaatag aaaagatatt
    23701 atttttagcc ctggtgttgt acctgctgtt gctattttag taagaatatt aactaattct
    23761 aatgaaggcg tgataattca aaagccagtg tattacccat ttgaagctaa ggtaaagagt
    23821 aataataggg aagttgtaaa caatcctcta atatatgaaa atgggactta tagaatggat
    23881 tatgatgatt tggaagaaaa agctaagtgt agcaacaata aagtactgat actttgtagc
    23941 cctcacaatc ctgttggaag agtttggaga gaagatgaat taaaaaaggt tgtagaaata
    24001 tgtaaaaaat atgacctatg gataatagct gatgagatac attctgattt aattagaaaa
    24061 ggatttaaac atactccttt acagtcatta tgcccagagt acaaggataa aatagttaca
    24121 tgtatagctc caagtaaaac atttaatcta gctggaatgc agttgtctaa tataatagtg
    24181 aataatgatg aactaaaaaa gaaatatcaa gaagaggtta cagctgttgg agttgcaact
    24241 tcaccaaatc cttttgctat tgtagctaca atagcagcat ataataaaag tgaagactgg
    24301 cttaatgaat taaatgaata cttagataat aatatacaat ttattgatga atacttaaaa
    24361 gaaaacctac caaaagtaaa acttgtttat ccagaaggaa catatctagc atggttagat
    24421 tttactgctt atggattgaa tgaagtagaa cttgaggatt taatgtttaa aaaagctaat
    24481 gtattatttg atgaaggtta tatatttgga aaagaaggaa taggatttga aagaataaat
    24541 gtagcttgtc cacagtcttt attaaaagaa tgtatgggca gattaaagac tacatttgaa
    24601 aatttataaa gtataggtaa aaagtaataa agtgtttaaa aataaaaaaa taataagctt
    24661 gacaaatttt aactaatcac ttatcatact attatgaata aatagaaaac ataagagagc
    24721 taaattttat tgaattaaac tcttaaagac tttgaaagga agagtagtta tagaatgtaa
    24781 ttaaagcgag ttggtgatgg tgtgagacca atatgaagtc tatagtgaag aacatcctgg
    24841 agttgctaac cgaaatttta aaagagtagg cttagtcgga accaaaccgt tatcatattg
    24901 gggtgtatcg agtaatatct gtacattgtg agctgggttt gaatttattt caaactaatc
    24961 agggtggtac cgcggaaaag caacctttcg tcccttttat atagggatga agggtttttt
    25021 taatggaaaa atatataaat atagggagtg aatgatatga gcacaataat accaaaggat
    25081 tataaaagta gtttgaacgt aattgataca caaatagcta taaaaaaatt aaaagatttt
    25141 tttgaaatga gactaagtaa tgaattaaat cttataagag tttcatctcc gttatttgta
    25201 ttgccagaga cgggtgcaaa tgataattta aatggagaaa aggctgtaag ctttgatata
    25261 ccatttatga ataaaaatgc agaaattgtt caatcacttg caaaatggaa acgattagct
    25321 cttaaaaaat atgggtttga agttggcagt ggtttatata cagatatgaa cgcaataaga
    25381 aaaaatgaag aattagacaa tatacattct ctttatgtag accaatggga ttgggaattg
    25441 gttatagata aaagtagtag aaatgaaaag actctaaaag atgttgtgaa aagattgtat
    25501 ggagtattta aggatactga aatttttgta tgtagtatgt atgaagatat aaaagaaata
    25561 ttaccagaag aaataacttt tataacatca caagagttag aagatatgta tccggaatta
    25621 tcaccaaagg aaagggaaga taaaatcgta aaagagaaga aagcagtgtt tataactcaa
    25681 ataggaaaaa cattaatatc aggagaaaaa catgatggaa gaagccctga ttatgatgat
    25741 tgggaattaa atggagatat attattttac aatcctgttt tagattcagc actagaatta
    25801 tcttcaatgg gaattagagt tgatgaagaa tctcttgata gacaattgaa acttgctgga
    25861 tgtgaagaga gaaaagagtt tgactatcat aagatgcttt taaatggaga gcttccatat
    25921 acaattggtg gaggaattgg tcagtcaaga atatgtatgt atttcttaca aaaagctcat
    25981 ataggagaag tacaagttgg agtatggcca caggatatga ttcaaaattg tagcagtgca
    26041 ggaattgaat tattataatt taaatataag ctaattaata aaatttatgt ctaatatgtt
    26101 catcaaatta attatatcgg ttataatgta gaataaccta taattataag aggtgataaa
    26161 tatggatttt ctaaaaataa ttattaatat agttttagat attttaaaaa aaattttggt
    26221 gagatttaaa aatgctaaat ttggtttggt ttttgtattt gatttactta aactacctga
    26281 ttttatgaca gataaaagaa tcaatatagc tgataaaata aaagtaattt ctgtattaat
    26341 ttttactata tcttactttg tatctggggt tgatataatt ccagagatga ttgctggggc
    26401 atttggtttt atagatgatg tgatagtttt aatttggagt ataggtatag tgaatgaaga
    26461 aatcaataag tatagagtta ttgcaaaaaa agataaacat tcaactataa ttgaaaatgt
    26521 aaatttttct ataaaagatg aagaagaata ataatttata tgtgtatgct aacatattat
    26581 ataacatcat atattactag atagtagcta aatcctagtt tttgctactg tctagtgata
    26641 aaaatttgac tgacctccaa ctgagaaaca aaaaatatac gattaactaa catccaacga
    26701 acataaaact gactattatt taaataagat tttgctcaaa ttttcagata tttctttttt
    26761 cacttcttct aaaacatgag agtatttatt tatagctatt tttatatcta tatgacctaa
    26821 tctgtctaaa atagtttttt tattagttcc atataataac atcaaagtta catttgtatg
    26881 tctaagctca tgtaatttta tatatttaaa gatgttttta aaagatttag actaatatca
    26941 taagtattct taatacattg aataactatg attttattat atcaaatcta agttataaat
    27001 actatttgat gatagagtag ttgtatacag aaatatatag atgaactttt gaaaaagtaa
    27061 taaagtagag gattatataa ttaaacataa tggataagta gaaggagcag aaccaatagt
    27121 atagaaggtt ctttttttat gcgtttagat gatttttaag tcttgtttta tgttaaaata
    27181 ataggtaata cagatataac aatagttttt ttagcaataa atatatttat aaaattggca
    27241 atattaagaa tagcatttta tgctttgcta gaatgcttaa gagcaataaa aacacataaa
    27301 cttaatggtt ctcttgtaat caatggagga aataagaaaa gtcgcaatgc tggtttgtat
    27361 attttttcta gaattagttg acatacttat aaattttaac tttttattta tgttgctata
    27421 agattgggtt gatttcttat gattaaataa tctaggaata tcagaatttt tctttatttt
    27481 atttattttg tataaaaatc taagtatatt aaaaaatatg tacttaaatg gattaccagt
    27541 tattaaagat taaaagagaa aataggtagt ttattagata ccatggcaga tgaatcaact
    27601 attaaaggag gagaataaat aatgaaaata tgtataacag taggacacag tattttaaaa
    27661 agtggagcat gtacttctgc tgatggagta gttaacgagt accaatataa caaatctctt
    27721 gcaccagtat tagcagatac atttagaaaa gaaggtcata aggtagatgt gataacatgt
    27781 cctgaaagac aatttagttc taaaaatgag gaaaaatctc ataaaatacc tagagttaat
    27841 agtggaggat atgacttact tatagagcta catttaaatg caagcaatgg gcaaggtaaa
    27901 ggttcagaag tactatatta tagtaataaa ggtttagagt atgcgactag agtatgtgat
    27961 aaactaggta cagtatttaa aaatagaggt gctaaactag ataaaaattt atatatctta
    28021 aatagctcta aacctacagc agtattaatt gaaagtttct tctgtgataa taaagaagat
    28081 tacgagagtg ctaagaaact tggatatgaa ggaatggcta agttaattgt agaaggtata
    28141 ttaaataaag gtgttgcaaa taatgaggtt aagcaaatgt ataaacatac aatagtgtac
    28201 agtggtgatg ataaagtgtc agcagagatt ttaggattat attataagag ggcaaaagaa
    28261 aattatttag tttcagatat aaaagactat gagccacatc aaacgcaaaa tctttatgtt
    28321 ataggtggtg agacttgtaa taaaatgaaa gaaatgagca atactacagg agaaaaattt
    28381 acagagattt attctgatga tgtatggtca acaatggata aggctataga gtttgtaaaa
    28441 gaaaaattat aatttaaaat ttttatttaa acaagaatgt agataagaaa aatttatatc
    28501 aaaatttttc ttatctattt tttcttataa atatatttat taaagttata aaagcatata
    28561 tttctagaaa aaatgtgttt tttgactatt tatgcgtttt tgatgaccag ttagacaata
    28621 a
//
LOCUS       DAMKOJ010000049        26345 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000049 DAMKOJ010000000
VERSION     DAMKOJ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26345
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.051"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            257..595
                     /locus_tag="PC592_002285"
     CDS             257..595
                     /locus_tag="PC592_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4056249.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            617..934
                     /locus_tag="PC592_002286"
     CDS             617..934
                     /locus_tag="PC592_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4056250.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVSILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLILQIIDIIKK
                     NKI"
     gene            1084..1764
                     /locus_tag="PC592_002287"
                     /pseudo
     CDS             1084..1764
                     /locus_tag="PC592_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905814.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2105..2872)
                     /locus_tag="PC592_002288"
     CDS             complement(2105..2872)
                     /locus_tag="PC592_002288"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF4056251.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKEDIIKEAKELKGVCLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYISDIPLLFTFRSLAEGGEKVISKDYYTTLN
                     KEISSTGLVDLIDVELFMGDEVIDEVINFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQDEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELSSVLNLLHKSIN"
     gene            3633..4265
                     /locus_tag="PC592_002289"
     CDS             3633..4265
                     /locus_tag="PC592_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF4056252.1"
                     /translation="MTIPNSTKVYPRNNDYQTVYLKNVITRENIEVGDYTIYNDFCND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHTLKSKSTYTFPIFYEEW
                     GLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVHIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNNTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDELV"
     gene            complement(4638..5507)
                     /locus_tag="PC592_002290"
     CDS             complement(4638..5507)
                     /locus_tag="PC592_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4056253.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELIELRKLGVKMIYLGLESGSNEVLEDIKKGFNSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGKISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(5603..6460)
                     /locus_tag="PC592_002291"
     CDS             complement(5603..6460)
                     /locus_tag="PC592_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4056254.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKKNNRKFN
                     IKNKIFKGIGILFVLILLSFFIWINKTYEPQKLAKEALISNSKVEVTVKENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVVASNFARDNKLIDGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNLS"
     gene            complement(6675..8693)
                     /locus_tag="PC592_002292"
     CDS             complement(6675..8693)
                     /locus_tag="PC592_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF4056255.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYIFSYDLK
                     RAVYVPFGLMYIFMVSIPVGISEFPMRLSALAAGAVIIMIAQFVMNRNRMKNIGDKEL
                     ISICDELLEKISLLKNIINDDSSISKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERINLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEVNYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKI
                     KSRDEKKAERKSNIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIDMYKGIVKNIIDEVNKSIENVADVYYIKNLLLVPSLIEDRIMLINAI
                     YKDKYQEDFLENQKLLISNMYNLYINVNKNKIQDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKTLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEVA"
     gene            complement(8965..9741)
                     /locus_tag="PC592_002293"
     CDS             complement(8965..9741)
                     /locus_tag="PC592_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF4056256.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALILGLIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     VLCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSIANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(9798..10769)
                     /gene="asrC"
                     /locus_tag="PC592_002294"
     CDS             complement(9798..10769)
                     /gene="asrC"
                     /locus_tag="PC592_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF4056257.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLTIVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTKFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDGDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDENSIIKIILNTYKYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGVKYL"
     gene            complement(10782..11573)
                     /gene="asrB"
                     /locus_tag="PC592_002295"
     CDS             complement(10782..11573)
                     /gene="asrB"
                     /locus_tag="PC592_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF4056258.1"
                     /translation="MNPYIPVNAKILDIVKHTDKEWTFRVNCDTKGVLPGKFYEISIP
                     KYGESPISVSGYGENYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIAGFKSPKDVLFADDLKRWSKKLDI
                     LVTVDGADEGYSGNIGLVTKYIPELDIKNINNTSIVVVGPPMMMKFTVGEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDNTYICLDGPVFDYSYAKNLID"
     gene            complement(11574..12581)
                     /gene="asrA"
                     /locus_tag="PC592_002296"
     CDS             complement(11574..12581)
                     /gene="asrA"
                     /locus_tag="PC592_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF4056259.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVSIPFKGTFSDTDVIRYK
                     EVNSFEEMEFTKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIREKVKFVLVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEIFNGETTEFNIDYVTDNLISVDVPENIDSNEMIRNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVTSKEE
                     I"
     gene            complement(12972..13661)
                     /locus_tag="PC592_002297"
     CDS             complement(12972..13661)
                     /locus_tag="PC592_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF4056260.1"
                     /translation="MSKLKDYNIDKVMIFNKLSTKTKNQLKEKAKLKRLQKKEILFYE
                     KDSLDSVYMLLEGKVSIFKISENGERKVIFILNSGEVINDITFDSSKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQSDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(13724..14572)
                     /locus_tag="PC592_002298"
     CDS             complement(13724..14572)
                     /locus_tag="PC592_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF4056261.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(14591..15478)
                     /locus_tag="PC592_002299"
     CDS             complement(14591..15478)
                     /locus_tag="PC592_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF4056262.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGLIIDKSSLDTEAKEKGGEGIL
                     SKIKGIVKKYIKENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEIEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNINGSSFQELASTSSLIKKVAKIKNLNENELNGKIIFDLAKNNDEGCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(15536..16339)
                     /locus_tag="PC592_002300"
     CDS             complement(15536..16339)
                     /locus_tag="PC592_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056263.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESVIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NAGCATLSKHYNIENKYVIWIQGESDAKYGSDALYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACNECDILCVGSKIAMQFHDKGLTIDDVHYTQE
                     GLNILGKDLCKNIYKYHTTKEKELLSDTIDLSEARRYIYELEKISKKFV"
     gene            complement(16499..16951)
                     /locus_tag="PC592_002301"
     CDS             complement(16499..16951)
                     /locus_tag="PC592_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF4056264.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEEGDFL
                     PLDGKNNGYVELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(17081..18583)
                     /locus_tag="PC592_002302"
     CDS             complement(17081..18583)
                     /locus_tag="PC592_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF4056265.1"
                     /translation="MVGFTWIDFTILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIVVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YCMPEVTSWAYSLITITTSVVVGTIFSAIEAKVKAKVSLPRAETTVYYEK"
     gene            complement(18616..19482)
                     /locus_tag="PC592_002303"
     CDS             complement(18616..19482)
                     /locus_tag="PC592_002303"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF4056266.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            complement(19567..20238)
                     /locus_tag="PC592_002304"
     CDS             complement(19567..20238)
                     /locus_tag="PC592_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF4056267.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCISTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKRVFELGVYSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(20514..21005)
                     /locus_tag="PC592_002305"
     CDS             complement(20514..21005)
                     /locus_tag="PC592_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF4056268.1"
                     /translation="MEGNINNKVDDKFSKVKKKFGNGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSIDDNSFDKFCDELLELDKLIYEKNMEINEMEMVESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIVCGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            complement(21027..22391)
                     /locus_tag="PC592_002306"
     CDS             complement(21027..22391)
                     /locus_tag="PC592_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF4056269.1"
                     /translation="MGEKKINNMNYSHNNYSKTTGEPTRKIKNSHITLKNKEEKICSS
                     CNKENNTKDNYCKFCGNELYEITSLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKSVLANSIGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIKTFIL
                     GYVLVLIILFVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIKPIVVFSIYY
                     AFLMGMLALFSTFILDSNINFFNTTSYGATLIMQFKVLQAIVISFIYSFVISLIGYKL
                     NSAD"
     gene            22810..23985
                     /locus_tag="PC592_002307"
     CDS             22810..23985
                     /locus_tag="PC592_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4056270.1"
                     /translation="MNLEKIKKFWGFPLDKKHKENVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFATPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKLGESVIVFGGCFLF
                     LNFFLPGIQTIPGNEFSNIVNTFFITSLAVFVSTMLYRSRVFTYYDKLLISQQYEEIY
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCDEEDAKLKSECLRKII
                     ETCNFERDDIPLKCVTVSIGVYTNKIERTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(24158..25555)
                     /gene="asnS"
                     /locus_tag="PC592_002308"
     CDS             complement(24158..25555)
                     /gene="asnS"
                     /locus_tag="PC592_002308"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF4056271.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFVRITYTKAVELLIESGHDFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(25632..25865)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(26023..26217)
                     /locus_tag="PC592_002309"
     CDS             complement(26023..26217)
                     /locus_tag="PC592_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF4056272.1"
                     /translation="MENKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVTEAKDWVDNGSKL"
BASE COUNT         8974 a         4350 c         2638 g        10383 t
ORIGIN      
        1 aataaaaaat gctataatta acatattatc aattcgtttt attattgtag tacggctatg
       61 aaattataaa aatatttgtc taattaaaaa tatgatttat ccatatttgt ttattgtaga
      121 tacagactat acaaaaataa atagcactta tttcagtata aaaacatata tagtctatat
      181 ttaaactaaa aaagtataaa tagtctatat aaaacaactt aaactatgaa tataatctaa
      241 ggtggaggga taataattgg caaatatagg aaaaataata ggagatagaa taaaagtcta
      301 tagaacaaaa ttgggatata gtcaagagtt tctagcagaa aaggcaggtt tacatccaac
      361 atatattggt cagattgaaa gagctgagac aaatacatct atcaatatta taatgaaaat
      421 tgctactgct ttagacatac cacttgaatt gttatttgca aatattatta caacagaagg
      481 cgttgataac tctgtacctt tagaatgtta tgaaatgatt aataaactaa ctgaaaaaga
      541 acaaattgca atgctagagt taataaagtg catcattaaa tacaaagaaa tataagcgag
      601 ggaaatagta acaataatga attatatagg taaaagactt aaagaagaac ggaaaaaagc
      661 aaatttaact tcaaaagaat ttgcaaatat ggttggagta tcgccttggt atataactca
      721 aatcgaaagt ggtaaaaaga atccaagtct taaaacattc ataaaatttg taagtatatt
      781 aaatatctct gcagatgttc ttataaaaga tattacttcc actggaaaga catatttaga
      841 aaatgatata aatgaagagt taaaagactt aaattcaaga gaactaaatc tgatattaca
      901 gattatagac atcataaaaa agaataaaat ataattcttt atattttata taaaaaaaaa
      961 ggttatttga aataaataac ctttttttgt ctttttgtgt taacattgtc ttatagtgct
     1021 aatgagtact attagaccat gttctatggc cttattttaa tataaaacga ttggagatag
     1081 gctatgattg tgattgaagg tagcgataaa tttaaaattg caaaagaata tattgatgta
     1141 gaatatactc tttttagcaa agtaactttt aagtatgaaa agttaaaatt taaagataat
     1201 gctgaattag aaaaaattaa aatgtttaaa tataaaaatg gctacatccc taataaatta
     1261 aacctttctt taggatatgg attctcttct tataaaaaac aaataattag agaaactgta
     1321 gatactttaa gattgacaga aattttttca agcgagaaca tagaagatat taaatttata
     1381 aaagatggta caaaaaaatt agaaattagc atagagaaag ttgtgaaatt taaacgttga
     1441 aaaaaaagaa attatgtttg ttgctattgc cctgatatgt atagagacat aaaactcgac
     1501 aaagaatcta tcgataaaat atacaacaga agaaaaataa aaatagaaag agaagttaat
     1561 atttttgaag atgaggatgt tataataaac aaaaaagtat tgaaatttcc aaaatcttgg
     1621 acaaagaata tgcaaaaata ttggctaagt gaaaataagt atcccataca ttctactgta
     1681 attgatgatg atagatataa atgttgtaat gtacaatata caaagaatag agtgataata
     1741 ttatattaca tatataacct ttaatataca taattacaaa aaagtaatta caaatacaca
     1801 taatacaaat atatcttcta ctttagataa aacagttatt ataaaaactt actatctata
     1861 aataatagaa atgctagtat accatctata atccaatgtc tagtaggttt taatggcata
     1921 ttttaaatat gccatagttg atttataaga tttttatacc actttcaaaa tacacactaa
     1981 atagttgctt ttcagatatt acacttaatt aaccaattta aattttacta tctgaaaagt
     2041 tttttatatt taatttatat atcttcaaaa ataactccta atatttctat ataattatat
     2101 taaattaatt aatactctta tgtaataaat taagtactga gcttaactct ttaaatgata
     2161 tttgacctgg tgctgaaaca ctttttgcag ctccaaaagt taatgcagaa ccaaatattt
     2221 ccccacacaa tctgcttata actcccattc ccgacattga cattgttatt attggtctat
     2281 ctgcataaat tttaaacatt tcatttgtag cttcaagtag aactaacaca tctttttcat
     2341 cttgtggcat aacagctatt ttgggtaaat ctgcgcctaa ttcctgcatt ctacataaac
     2401 gagatacaat ttcttctttt tttggagttt tattaaagtc atgattagat ataattactt
     2461 tcacttcttt tttatgagca aaattaatta cttcatctat aacctcatct cccataaata
     2521 actctacatc tattaaatct actaaacctg tactagaaat ttctttattt aaagtagtat
     2581 aataatcttt tgatattact ttttctcccc cttctgctaa acttctaaat gtgaataata
     2641 aagggatatc agatatataa cttcttaatt catagagaac ttccttaact tctttaatat
     2701 tttctacatt ctcaaaaaaa tcaactcgcc actctataat atccaaacat actcctttta
     2761 attctttagc ctcttttata atatcttctt tatttttacc gataatcggt acacaaattt
     2821 taggtctacc ttctccaata gtaatatttt ttacttgaac ttttcttttc atattctcct
     2881 ccataatcag aaattctata tgattttaaa ttctattttc tgcataattt aattatacat
     2941 tataaatgct acacattata aaaatactaa tttaaaaata atttttattc taattcttaa
     3001 aacaatccca catattttag aaaagatact ctataatata aaaacacttc tttcttatct
     3061 aaatttattt taacattcta taattttcat aacattactt aagttttatc tatataatca
     3121 atattattct ggatgataat agaattaata tataaattat agtataatta tatagaaata
     3181 actcgaattt tactacttat gaagaaattt gatatcaata aattcaaatc atttgcatta
     3241 cttcagagtt ttggctaaag ttaaacacca tactaaaccc aaaatagatt ttacagctat
     3301 acttcaagag taattgattg taatagtacc atataatcat cctttagcat taagtgacag
     3361 tgtagattaa aaggataaca atgttaatgt tctttaaatt aaaaattatt ttgtatataa
     3421 aatatattaa attattgcaa gctttattgt tttgatatac aatcaactaa gcatatagcc
     3481 tttataaaat actaaatagt taaaagtctg tttttaaaaa caaaatgtat aaattaaaat
     3541 atagatacta tcaaggagtg attctgtgaa gagatgtatt gtaatagtgg aatagtcaaa
     3601 aacataatat atatcaaagg agagatttaa atatgactat tccaaattca actaaggtat
     3661 atccaagaaa taatgattat caaactgtat atcttaaaaa tgtaataaca agagaaaata
     3721 tagaagttgg agattacaca atatataatg acttttgtaa tgacccaaga gattttgaga
     3781 aaaacaacgt attatatcat taccctatta acaatgataa attaataatt ggtaagtttt
     3841 gctcaatagc atgcaatgca aaatttctaa tgactagtgg aaatcacaca ctgaaatcaa
     3901 aatccacata tacctttcct atcttttatg aagaatgggg actcgatatc aatcatataa
     3961 cggatgcttg ggacaataaa ggtaatatta taattggaaa tgatgtgtgg ataggctatg
     4021 attctataat tatgtcaggt gtacatattg gcgatggtgc aattattgga acaagagcag
     4081 ttgttactaa tgatgtccca ccatattcta ttgttggagg agtacctgca aagattataa
     4141 aaaaaagatt taataataat acaatttcaa aattattgga aattaaatgg tgggattggc
     4201 catataaaaa aatccaatca aacattaagc atattcaatc aggaaatata gatgaattag
     4261 tttaatcttt tataatttat atatattaaa ttttacttta ataatccttt ttataagaat
     4321 tttttcaaga tttgtatatc attttaatat atataaattt aatacaatac taaacaaaaa
     4381 taaaaagtaa agttgcttaa tataaagtta ctttactttt tattatttaa attcatgggt
     4441 ccattataat atgtaaaatt ctattaaacc agttcacatt ttcatcatta ttgatagcct
     4501 atatatgaac ataccatttt gttttttaac aaaaaaatca tgctatatta atagtaaaaa
     4561 actattaata tagcatgatt ttttgtatct aaacaatctc agtatttatc tataaatata
     4621 gattgatata tcaaaaacta cagtcttcta tattcttctc tttttaactt ttggttactt
     4681 agatagtaat caatttcatc aattagacgt tgtttgtcat caggtaatac accttttaaa
     4741 ttagcataat ttgatgcatg attacttcta aatacaattt tttcattggc atctatattc
     4801 tttatcatct ctttaatttc ttgtaacaca gccttatcct ctagtattgt aaactctcct
     4861 gccttaagta aatcgtaaag ttcagtatta ggttctacca ttaaactaag tacacctaca
     4921 taatctggtg aaatttttcc taacattttt cctgtatcaa cggcatgctg atgtgttttt
     4981 ttagttcctc caagacctgc tattacagtg gctgataatt taatcccact ttttttaact
     5041 tttctaccaa cttttattaa ttgttcacta ttaaaacctt tcttaatatc ttccaatact
     5101 tcattgcttc cactttcaag ccctaaataa atcattttaa caccaagttt tcttaactct
     5161 ataagctcat catcagattt tttctctata gatttaggag aaccatacat agtaattctt
     5221 tcacactctg gaaaaacttc ttttatatat aaaattatgt ctcttaattt ctccattggt
     5281 attatcaatg catctccatc tgctaagaat attctttcta catgtttata atatcttcta
     5341 aatatatcaa tttcattttt tattacttct agtggcttta ttttaaattt tttagatttg
     5401 tacatactac aaaacgtaca tttgttgtga gaacatccta gtgtgacttg tattataaga
     5461 ctataagcct cacttggcgg tctgtaaagt ggcatatcgt attccatatt aaaatccccc
     5521 ttgtaataaa atatttattc tattatatta ttaatattta ctttaaataa taacttataa
     5581 aattatattt tttaatttta gtttaagata aattctttaa aaatttaatg atactattgg
     5641 cagtaatatt aagttgtttt tcttgactta taatagcatc attatctccc ttttgttttc
     5701 catagtctcc aaattgtgca tgatttcctc cttcaatttc aacataagtt gtatcatcag
     5761 gaagtttttg ttttgattct acaagacttt taaaattgac tacaccatct ttgctccccc
     5821 atatagatat aacttttttt cctaattctt tcaactcatc tcccattgga taagaagcta
     5881 aaaatacaac tccatcaatt aatttattat cacgtgcaaa atttgatgct acaactcctc
     5941 ctaatgaatg acctcctatt acccaatgtt ctatgttgtt gtaagaatcc ataactttct
     6001 gcgccttatt agttccaagt atagctagat taagtggcat ctttacaatt acaacctcat
     6061 atccactttc tgctattttt cttgcaagtg gtgcataaga ttctatttct actttagctc
     6121 ctggatacaa aattaaacct ttagaaactt ttcttccttt tggtgtaaat gaaatgtttt
     6181 cttttacagt tacttcaact ttactattgc tgattagagc ttcttttgcc agtttttgag
     6241 gttcatatgt tttatttatc catatgaaaa aactaagcaa aatcaataca aatagtatac
     6301 ctattccctt aaatatctta ttctttatgt taaattttct attattcttt ttatcatctt
     6361 tgttttcaac ctcatcataa agtaaaggtc tttcgagttc catagttata ctaaatgtat
     6421 catatttctt attgcgtttt acctttacat ctttactcat aaatctaacc cccataatat
     6481 ttgaatacta ttatagttta tcctaagtaa attgtttttt caaccaatga aaaaaatcaa
     6541 tattttaact attttcatat aaaattcata aatatatgtt ttttgttttt tatatattat
     6601 tttcttttaa tattttataa aacaaatagc catatacttt attttaaata tatggctatt
     6661 ctataattta atatctaagc tacttctttt attgaaactt tagttatatt acttattcta
     6721 tacatttctt tgacaccatt tagagtttgc agtaagttta gacatattat cttgtctcct
     6781 agagttttag tatttacaat actctctaaa attacgcttc ttccctcatc atacttatct
     6841 acattgtaat ttgaaatata attagtatct ctcaatattt tttcaacatc ttcatcttgt
     6901 attttatttt tattaacatt tatatataga ttatacatat tacttattag taatttctga
     6961 ttttctaaaa aatcttcttg atatttatct ttatatatag catttatcaa cataattcta
     7021 tcttcaataa gtgatggtac caataataaa ttctttatat agtaaacatc agctacattt
     7081 tctatagact tattgacttc atcaattata tttttaacga ttcctttata catgtctatc
     7141 acatgttgat agcctgtttt agcatcatat ggtaatataa acttatttac tattaatgca
     7201 ataattgctc ctaatgctac atatgaaatc ctgcttattg ttaaaacatt tgggtctccc
     7261 ataactacag ctgaaccaag agctgaaaca gttacacata ccattaattt tctataatca
     7321 actacataag agtttatata tcctgctaaa agaactatta acgaccttaa tgtactatct
     7381 tttattattg aaaataatac aataaatatt acagctccta taaatgtacc ttctattctt
     7441 tttctagacc tttgtataca attttctgcg taaggttgtg ttaatgaaaa aacagttaac
     7501 attatccatc ttccatccct taaatggaaa taatccataa taaaacccgc tacagctgta
     7561 gctaaagcaa tctttactgc ataagaaaat cttatagaat ttaaattaaa gtttttctta
     7621 tatattgata gtcgtttaaa ttcatgaggt atatttgatt ttctttcagc tttcttttcg
     7681 tctcttgatt ttattttttt ataatctact aaaaactcat ataaattttc taaaacacta
     7741 taaatttctt ttaaatttat atttttagta tcctgagcaa taacataatc tctaaatcct
     7801 aatatctctt tatcagttat ggtatcttta ttttctaaac acatcttaat atagtttact
     7861 tcttttgttg ctacaactag aacatctgat ttactattta tgctactttc ttctaaaata
     7921 ttttttatat cttcatcttc aaattcttta ctatcctttt tgtatctttc taggattaaa
     7981 tttattcttt ctaatgaaaa taaaatattc attatgtcta tacctctaat acttatataa
     8041 aagtcatctt ttctattatc aaaaataacc attttcaaat ttttagatat agaatttatt
     8101 ctataattac agctatctat ttttctcata ctagatttac ttatagaact atcatcatta
     8161 ataatatttt ttaaaagact aattttttct aataattcat cacatataga tatcagttct
     8221 ttatctccaa tatttttcat cctatttctg ttcataacaa attgagcaat cattattata
     8281 actgctccag cagctaaagc cgacaatctc ataggaaatt cacttattcc tacaggtata
     8341 cttaccataa atatatacat taggccaaaa ggtacatata ctgctctttt taagtcataa
     8401 ctaaatatat accctattat aaataatgct ataaaattta ataaaacgcc taaatacata
     8461 ttttgtactg caaaaaatga tagtattcct aggattatat ttattgctaa atactttagt
     8521 aaatttttaa ttggagaaat agttaaatct ctttccaata gtgttagcat agctgttact
     8581 ataccaacac ctataagtgt gtttttactt ccaaataaat atatgaatat agaaataaat
     8641 gctattataa aaataaacaa ttttgttttt gatattacta gtttctttgt cattatatcc
     8701 cccctaaaaa tttcaacaag accaatttta tcatatttgt tatcttattc aaaatactct
     8761 tttttacggt aggactttaa ctttttttac attttgaact atataatcta tatttaaacg
     8821 tattttattg catatatagt ttatatattt tcgtatgctc ccatatattt tttctttcaa
     8881 atattttttc aaaaatataa aaataactct ctcaacaata ctaaaactgt atttattaag
     8941 agagttataa tttatacaat aaatttaatt aagcttttct ttacccaata tataagttcc
     9001 aagacccata aataaagctc ctccaacaat atttccaagt gtcacagcta ctaaattata
     9061 aatagctcct ccaatagtaa ctgtacttat tgttggtgaa aataatgaaa cactataaat
     9121 tgtcatattt gctatactat gctcaaaacc tgatgttata aaggcaaata aacataagaa
     9181 tatcataatt atttttgcag tatcactatt agttctaaac gaacacaata ctgatacaca
     9241 taccagaata ttacataaaa cccctctaaa gaaaagagct gtaaatggca tggatgcttt
     9301 actagctgct gtatttgcaa aaaattcagc tacaggtcct ttatctacta gaccagttcc
     9361 tacaaatata agacctaaaa ttaaagctcc aattaaatta cctacccaac tgtatgccca
     9421 tattttagaa gtatctttta tacttacacc tttatttaac ataccagcag acataaccat
     9481 attgtttcca gtaaataact ctgttcctgt cattataact aaacttagtg ctattgcaaa
     9541 ggataacccc attactatct tagtcatagg tgaacctgca tcagtcaaaa gtcctccaat
     9601 agtaaatatc aaaagtatac ctattcctac ataaagtcct gcaaacgcag aagataccaa
     9661 atattttact ttacttgtgt ttaataaatt tatcttattt atagctgcat tagttaattt
     9721 atccaaagtt tctttatgca taattccctc ttccttctat taaattttaa tttattcaaa
     9781 tatatgtttt actcaattta tagatattta actccactcc agtatatgtt ttcatacatt
     9841 ttagttattt ctggaagttc tacaccttca agcgcccatt ttttaaactc cataaatcct
     9901 gttctatcaa ttatatatcc tatatgttct tttcctcctg gtgcatcttt atctatatac
     9961 ttttctacat atttgtaagt attaagtatt atctttatta tgctattctc atctacccat
    10021 aaaagaaaat cttctgctag tctagggttt ttctttcctg ttctacccat tatagctaat
    10081 ctatagtatt ttttctcatc tctagtccat gcatttgttg ggcaatttag tacacattct
    10141 ccacatccta tacatttatc tccatctctt accaccttat tattttctgt ttttaatgct
    10201 ccaacagata ttttagaaca tttttttaca cacgctccac aatttacaca tctatctttt
    10261 tcatatatgg gtaaagccat accaataatt ccaaaatcat tcattctagc ttttatacaa
    10321 tcatttggac agccagttaa agccacttta aaatgtaaat catttggaaa tatagctttt
    10381 tctattcttt tagcaaattt agttgtatta tattgagcct ttggacagac tttatttcct
    10441 atacatgctg ctatatttct tgtacccgct gctggataac ctgcattttt ctcactttga
    10501 tttatattca ttttttcaat aacaggttgt ataattttat ttatttcttc catatcttcc
    10561 atatttattc ctaatatttc aaagccctgt cttgtagtta tgtgtacctg tccattacca
    10621 tactcacttg caattttaga aactatagtt aaactctcag ggtcaataag cccaccaggt
    10681 actctaaccc ttaaagaagt ctcatatttt gtttttgtaa tcctataagc atttttcatt
    10741 acttttttgg tatttaaatc tcttatcaca aacttcgccc cctaatcaat aagattttta
    10801 gcatatgaat aatcaaatac tggtccatct aaacatatat aagtgttatc cattttacag
    10861 tgtccacatt tacctatacc acaacacatt tttctttcat aagaaaccca aatattcttt
    10921 tcatctaaat ctctttttaa aaattctcct actgtaaact tcatcatcat tggaggtcca
    10981 actacaacta tagaagtatt atttatattt tttatatcca attctggtat gtattttgtc
    11041 actaatccta tatttccact atatccttcg tctgctccat ctacagtaac taaaatatca
    11101 agttttttac tccatctctt caaatcatct gcaaataaaa catcttttgg tgatttaaat
    11161 cctgctatta atttaaactt ttcgcatttt tctttattgt tgtaaaaata ttcaactatt
    11221 cctcttacag gggctaatgc acttcctcct gccactacta caatttctct tccttcgtaa
    11281 agagatacat caaatccatt tccataaggc cctcttataa aaaaagaatc tccttcttta
    11341 taattaaaca actcactagt tacttttcct acatttctta ttgtaaagtc aatatagttc
    11401 tctccatatc ctgatactga tattgggctt tcaccgtatt taggtataga tatctcataa
    11461 aattttccag gcaatacacc ttttgtatcg caatttactc taaaagtcca ttctttatca
    11521 gtatgcttaa ctatatctaa tatttttgcg tttactggta tatatgggtt catttatatt
    11581 tcctccttac tagttactaa atcatttatt ttttctatac attttgaaaa tgatatgtat
    11641 tgtggacagg catcatcaca tcttccacaa ccaacacaca tatgatatcc gaatcttttt
    11701 ttaaaatcat gtattttatg catagtttta aatctcattc tttcaccttg tttttttcta
    11761 aaagaatttc cacctgctat atctgtatat ccatctactt gacaagaagc ccaaactctt
    11821 cttctctcac ctacattctc attttcctta tagaaaatat cctgcattgt aaaacatgaa
    11881 catgttggac atacaaaatt acatctacca catcctatac atcttgtatc atattcatcc
    11941 catatagaat ttcttatcat ttcatttgaa tcaatatttt ctggcacatc tacagatatt
    12001 aaattatcag ttacataatc aatattaaat tcagtcgttt ctccattaaa tatttcaaat
    12061 tcactatcct ttatgtctaa atacagtgta tctccttcta tatttaatcc aattgaataa
    12121 ttatcagttt tgttagaatc catactcaca caaaaacagt ttctaaaact ttccttacac
    12181 cctacaagta caaactttac tttctctctg atatttttat aaaaataatc tttttcttcg
    12241 ccattattta gatatatttc atcaagtctt tttatcccat ttatgtcaca agctctcaag
    12301 aaaattaaaa ttttcttgtt gtctaaatcg ctttccttaa actctttttc agtaaaataa
    12361 aataatactt gatttatagg aagtacaact tcttttggtg agaaatttgc tttcttggta
    12421 aattccattt cttcaaaaga gtttacctcc ttgtatctta taacatcagt atctgaaaaa
    12481 gtacctttaa atggtattga aactggtgca aatatcttgt agtctttttt tagataattc
    12541 agaccttcat tgaatttaga tgaatctaat tttaatttca ttcttatcac ctttcttata
    12601 ttttagtttt acttacttct tatcttgttt aaatcttaac attttatttt ctatgcttct
    12661 gtgataatta tcacagtttc aaaaataata aaaaaatatt aatagagttt attaagctct
    12721 attaatattt ttttattatc tatattattc gattacaaat ctagtcactt aaatacaatc
    12781 attaaataca ataaatctat tatctactca actttttgaa taatagagag tcttatttgc
    12841 ttttttatac aatttaggaa aggtaaaata aggattaata aattagacaa taaaaaagaa
    12901 tctataaata gattctccca ataatatttt taattaatta aaatcctaat aataccctta
    12961 tttaatcata actaattatt tttaaaatac cttgataatt cagtttcttt aacgtaaaaa
    13021 cctttattat caatcttaat aagttcttct ttttgtaata cctttatcat tctagaaaca
    13081 gtctctcttt tacagccaag catatcagct aaatatgtaa ctgtaatatt tacatttagt
    13141 aaagtccatt ctccacagca aactccaaat tctctactta acctatataa ttttgctgcg
    13201 agttttttat ctacttttat agatatagaa tttttcaact gtctatataa acgtcttatt
    13261 cttctttcca tataagaaat aatatctttt gtaagttgaa aatcactttg cataatttct
    13321 aaaaactctt caatactata ataagctaca attgagtttt caaatgcttc acagccaaca
    13381 gtggagtttt tagaagagtc aaatgtaata tcatttatga cttctccact atttaatatg
    13441 aaaattactt ttctctcacc attttcactt atcttaaaaa tagatacctt tccttctaaa
    13501 agcatataaa cactgtctaa gctatctttt tcataaaata aaatttcttt tttttgtaat
    13561 ctttttagtt tagctttttc tttaagttga ttcttcgttt tggtacttaa cttattaaaa
    13621 atcattactt tatcaatatt ataatctttt aatttagaca tgtaatatct ctccattcct
    13681 aagtttttaa gagagctcta taaaacatta caaatttctt attttattca tttttaaaca
    13741 attttatagc atttgtagtt ttaatttttc tttcaatagc ttcattagaa agttctttta
    13801 ctacttgtgt atatactaaa tcaataatga agaattgtgc taatttagaa gatattgaac
    13861 cggtttccag tactgtttct cctgatacat aagataagtg tacatctgaa atatccttta
    13921 attcagaatt tttattttca gtaattgata taattttagc attattggct cttgcaagct
    13981 ttacagtttt tataatctcc tctgtttcac cagaatgtga aattgcaatt attaaatctc
    14041 cttcttccat tatggaagac atcattatca tggtatgact actgtcaaaa cttacacaat
    14101 taagacctat tctcataaat ttatagtttg aatcctgtgc tattatacca gaatatccaa
    14161 tacctatgaa gtaaactttc tttgcattta ttataagcct tgcacagtca tgtacatcct
    14221 tactattgat tatctccact gtgttctcta aagtggttac atttgaactt aaaagttttt
    14281 ttgctgtatc taaagctggc tcatcatttt gtatattttt atttataata ttttttttat
    14341 tgatagttga tatttcttgt gctaaagtaa ctttaaaatc ctgtaatcca ttaaaattca
    14401 ttttttttac aaatctagtt atggttgctt caccaatatt gctttcttta gctatttgtg
    14461 atattggttt ataaaacaca tcatctatat tttcttttat ataagctatt aataatttat
    14521 ctgactttgt gactttaaaa gttggtgatt ccaattgttc taaaatactc attaaaaacc
    14581 cttctattct ttatattttg tttaaaaaat tatataatgc cccaagcatt cccgcatcat
    14641 tttgtctctt tgcaaattct atattagtgt ttttgtaaac tctctctata agaacctcct
    14701 ttaatgcttt gtctattttt ggttttagga acttttcttg tgccataatc ccaccaccta
    14761 aaattactac ctctggattt attacataac atatatttgc gattccaact gctaatgatt
    14821 ttatcatatt atcgagttct tttaaacaac cttcgtcatt attctttgct aaatcaaaaa
    14881 ttatttttcc atttaattca ttttcattca aattttttat ttttgctact tttttaatta
    14941 gactgctagt agatgccaat tcttgaaaag aacttccatt tatattcata tatcctactt
    15001 cgccagcact attactaaac ccatttatca gtttattgtt tattataata catccaccaa
    15061 ttccagtacc tattgttaaa catatagaag atgttgcacc tctacctgct ccaagccaca
    15121 tttcaccaag tccagcacaa ttaacatcat tttcaacttc acattttata ttaaactctt
    15181 tttctatttc tttttttaat tgcataccct tatagtttgg aattaattct tctaatgcaa
    15241 atagtatttt accttcaact gggtcaacca tacctgcagt tgatatgcat ataccactta
    15301 tttcattttc ttttatatac ttttttacta taccttttat tttagataat attccttctc
    15361 cacctttttc ttttgcttca gtatcaagac ttgatttatc aattattaat ccatcttctc
    15421 taataaatcc atattttatt gaagtacctc caacatctat acaaacgtaa tttttcataa
    15481 catatctcca tataaattat ttttataaat tgataacact acttaaactc ttatattaaa
    15541 caaatttttt acttatcttt tccaattcat atatatacct tcttgcttct gataaatcta
    15601 ttgtatcgct taataattct ttttccttag ttgtatgata tttataaata tttttacaca
    15661 agtcttttcc taatatatta agaccttctt gagtgtaatg tacatcatca atagttaacc
    15721 ctttatcatg aaattgcata gcaattttgc ttcctacaca taatatatca cattcattac
    15781 aagcagactc ctgtgctgct gcaattcgtc ttgttctaat aaaatattca tcttctccaa
    15841 gccaataacc agttaaactt acaaacattt tatcaatcat acattcttct ttaagtctat
    15901 aagcaatctt ttttagactt tctttatagt acaatgcatc actaccatat ttcgcatcac
    15961 tttcaccttg aatccaaata acatatttat tttctatatt ataatgttta cttaaggtag
    16021 cacagcctgc attaaatttt tctatagtgt catttaggaa ccagttatta tcatgattcc
    16081 agttttttat tcttgaacca tcttttgcat tgtgaataaa acaaacttta tttccagtaa
    16141 gcttattcca ttcatttgaa aatgcaggtg ctatagtacc atcaccttct gaagtttcta
    16201 gctcacatct catatttata atttcatcag tacttaaata ttcaaaacaa ttttcatttg
    16261 gaatgacact ctctttggga ttccctaatc ctctagcatt gctttgtcct attaataaga
    16321 atacatctat attttccata agttaactcc tttacaaaat tttaaacttt taattatttt
    16381 caatttcctt ataaaaaact aaggctgaaa atagtaatct aactaaaatt tacgaagtct
    16441 cactaatcgc tgaaagttaa atcactattt tcagccctag tggttatata aattataatt
    16501 atctaaccaa aaccttaaaa atagcttttt tgatattttc tttttctaaa acttttattc
    16561 ctgtcatatg agcatcttct ggataacaaa ctaaaaaatc gccttttcta agttctacat
    16621 atccattatt tttaccatca agaggtaaaa aatctccctc ttcttcatat attttttgtt
    16681 ctaaattttc tataaaattt atatctattc gttcacatcc atcaagcatc aaatgaacat
    16741 ctatatactt cttatgagct tcccagaatc tatcttcttt ttcacaagtt ttatactcta
    16801 caatattcac aaaaatatca tcaccatcta ttgtataagt acctttttca taatctatta
    16861 atgaattatc tttagcatat tcaaaacatc taagtaaatc ttcatgcaat gttgaatatg
    16921 tcttactatg atttatattt ccaaatatca taagcactat ctccctatat aattataaag
    16981 tctattttta tacttttata tataaagtat attatacaat cttatagagt aactaaatta
    17041 tttatctaat cactctataa gacaatttat catttaaata ttatttttca taataaacag
    17101 tagtctcagc tcttggtaaa gatacttttg ctttaacttt agcttctatt gcactaaata
    17161 ttgtacctac cactacagaa gtagttattg ttattaaaga atatgcccaa gaagttactt
    17221 ctggcataca gtattttaaa taaacaacca aaattgctga tactataaac ccaacatatg
    17281 ctcccatctt agttgctttt ttacaaaatg caccaagtac aaatattcct gctaagacac
    17341 ctagtactag acccataaaa ctattgaacc attcatatgc tgactttatt tctccatttg
    17401 ctaatactat tgcaacaact atagaaagta tacctacacc taatgatata tattgtgcta
    17461 tcttagtttg tttttccata cttatatctt ttgttatgat agtttgtata tctaaagtcc
    17521 aacttgtagc aactgagtta agccctgttg ataaagttga ttgagaagct gcatatattg
    17581 ctgcaagtag tattcctgtt atacctactg gtaactcata agctatatat gatgcaaata
    17641 cttggtcttg ttgaactgtt tgagctaaat ctggattttg agtatagtat ataaataaac
    17701 aagttccaat taaataaaat actgttgcaa gtcccattga taaaacacca tttccatatg
    17761 tcattttatt aagttgcttt atatcagttg ttgtagtaaa cctttgaact atatcttgac
    17821 tcgatacata tgatgaaaaa gtattaagtc cagctccaac aaatattata aatgcacttg
    17881 tagatagtat atttttatca aacataactt cattacttgc taagaacttg tgtccagttg
    17941 taagagtatc cattactgtt ccaaaaccac catttatact tgctattaaa tagaataatg
    18001 ttcctgtaac acctactatt agtaccattc cttgtataaa atcggtccat aaaacagctt
    18061 ttaatccacc tgtatatgag taaattattg ctattacacc cataactatt atcagtacat
    18121 ttacaggtat tcctgtaaga ccagccagaa ctattgatgg aagatacatt ataatagaca
    18181 tacgtcctat ttgatatatt ataaacatta aagctccaag cactctaaga cctttgcttt
    18241 cgtacctcat ttctaagtac tcataagctg tatcaatttc taacctacta tatagaggta
    18301 agaaaaattt tattgttaaa ggtatagcta taaacatacc taattgtgca aaccacaaaa
    18361 tccaagtccc accataagaa tttcctgcta atgataaaaa cgatattgga cttaataatg
    18421 tggcaaatat tgatactgat gtaacccacc acggaatagt tccatcacct ttgaagaact
    18481 cttttccctt catttccttt tttgaaaata acaatcctgc aaataaaact gccaataagt
    18541 aaaccactag tattgtaaaa tctatccaag taaatcctac catttgacta atcctcccat
    18601 actaaaagta ttttattaaa aatactttct gtatatttct tttgctcttg atttcatttc
    18661 atcagttgct tctttcatag gttgtctaca gtatccagcc tcaacacctt gttcttcaag
    18721 tagcaattta attgtttgat ataatccatt tcctaatata tctgttatta aatcattagt
    18781 cacatgttgt acttcaagtg cttctgatat tttttcattc ttagttaatt caaatatttg
    18841 tctagctctg acaccgttta cattaaatgt agaaccaatt gccccatcta cacctaaaac
    18901 tgtagctggt aacatcattt catcaaatcc tgcaaatatt aatttatttg ggaatgtttt
    18961 tctcattctc tctaataagt agaaatctgc tgctgtaaac ttaacaccta ttattttttc
    19021 attttcaaat aattctccaa actggtctaa actcatatca actccagtta aaaatggtat
    19081 agagtatatt attaatctat tatctacaga atttattatt gtattataat agtgttttat
    19141 ttcttcaaaa tcaaacttat agtaaaaagg tgtaacagca cttattgcat catatcctaa
    19201 atcagttgta aatttagcaa gctctacagc ttcttttaaa ttgactgaac caacttgagc
    19261 tattaatttt atttcttcct tcacttcatc tttagctatt tcaaatattc ttttcttttc
    19321 atcagttgaa agcataaagt tttcccctgt acttcctcct acataaagac catctacttt
    19381 acaaacatct atattatgtc taattatttg tcttaaccct ttttcattta tatttccttc
    19441 cttatcaaat gaaactaata atgctgaata aattcccttc atatctgttg ttctcatatc
    19501 tttacctcca attttaattt tcaagtatag ttaaatataa tagtttttta atttataaat
    19561 taatttttaa ttaatttcaa ttgctttaac aaatttttct gttattaatt gtggtcttgt
    19621 tattgctgaa cctacaactg atgaatagac tcctagttca aaaacccttt ttaaatcttg
    19681 aggagtattt acctttcctt ctgctattac aggtatttct aaatctttaa ctagtctttc
    19741 cattaataca aaatctggac cttctaacgt tttagtatat ggagtatatc cagatagtgt
    19801 agttgaaata caatctacac catattcttg tgctttgata gcctcatcat aatttgaaat
    19861 atctgccatt accagaacac cattttcttt tatatacttt ataagttctt ttaagtcttc
    19921 attatttggt ctaactctat tagtagcatc taaagctatc atttcacacc ctgttgtcaa
    19981 aagttcatca acttcttttt tagttggtgt tatatatata tctgaatctt cataatttct
    20041 ctttataata cctataacag gaagtccagt aacttttttt atctcaataa tatcttcaac
    20101 tccttgagcc ctaattccaa cagctccacc ttccatagca gccttagcca ttctccccat
    20161 tataaaagga ctatgaagag gttcattttc taaagcttgg catgatacta ttaatcttcc
    20221 ctttacctta tctagcattt tttcaattac ctcatttctg aaatttattt tcttgattta
    20281 tgtattaata ataacatgaa aactttttct ttgcaatatt ttttcatatt tttttcttaa
    20341 ctctatattt ttactgattt attctatata ttagtctgtt ttttatactt aaaagaaatt
    20401 ttatttcatt tttttggtgt ttattttcat tttgtataac cactattata tgtattctat
    20461 ataaataatt tcaataaaaa aacccatgta tactatacat aggtttccca atattattct
    20521 aaatccatta taatttttct tccacaacat ggacaaaatt cagcctctgt atctatctca
    20581 ctttcacaat aaccacaaac tataaaatca tcacattcat tttccaattc aaattttttg
    20641 ccacattcag cacaatattt atcatttaca tttccaacat agccacattc acaagttaca
    20701 ttactttcta ccatttccat ttcattaatt tccatatttt tttcataaat taacttatca
    20761 agttctagta actcatcaca gaatttatca aaactattat catcaataga atcttctcta
    20821 attttttgat atgtcaatat tcccatttcc aagaatatct ttgctttctt ttcttggata
    20881 tcatcaatct ctctatttaa ctttgatttt tctttatata attcaacttt aaattttcca
    20941 ttaccaaact tcttcttaac cttagaaaat ttatcatcta ctttattatt aatatttcct
    21001 tccacagatg ttccctccaa tcatatttaa tcagctgagt ttagcttata acctattaaa
    21061 gatatcacaa aactatatat aaatgaaatt acaatagctt gtaagacttt aaattgcatt
    21121 attaaagttg ctccataact agttgtatta aagaaattaa tattactatc tagtataaat
    21181 gtactaaata aagccaacat ccccattaaa aaagcataat atatactaaa tactactata
    21241 ggttttatac tatccgtatt atacttaaat cttagcttgt atccatttaa taataatatt
    21301 aacatagata atgctcccat tgcataaaac attaatttag tatctccaaa taaagatgaa
    21361 gaactcaaag taaacattga tactgttgaa tttattatgg ttactgaaat tccatttgca
    21421 aaagcccaca tatagctagc tatttgtggc agtatagtaa ataaatttaa tccatttgag
    21481 taactactca tatctagttc atttaagtaa ctactatcag atatagttag tacaaatagt
    21541 attattaata ctaaaacata acctaatata aatgttttta tagaatttga aaagagagat
    21601 aaatacatat tttccttttc ataacttttt ttataagtag ttatgtatgt acatataaac
    21661 cctaatacaa atccatttaa aaggacacta aaaaattcat aactatattc taatgcatat
    21721 ccatattcta acatactatg tgaactagtt tttacattag taaaaataga taaaatagct
    21781 aaaactaatc cataaaaaat tccaacacct atagaatttg ctaatacaga ttttgaatct
    21841 ctacatcttt ttctcataaa aattaagttt gatattaata ataccaaaat aggaattata
    21901 agtaatatta acaaacctat attggcattt ataaacccag aacccatcat ggtagacata
    21961 gatacactaa tttgacctaa gttgagagct aggattatat gtgctggatt tattaaataa
    22021 ctaatatcat taaattgaat agttataata gctttaaata tcaatgcaat aataaataat
    22081 ataaatatgg ttgtaaatgt tgttaaaaat actcctcttt tatttgcatg atatgaaagc
    22141 tcttttattt tagattttaa gtctagtttt gtttcaagtg gtcttaatga tgttatttca
    22201 taaagttcat ttccacaaaa tttacagtaa ttatccttag tattattttc tttattgcaa
    22261 ctagaacaaa ttttttcttc tttattttta agagtgatat ggctattttt tatttttcta
    22321 gttggttcac ctgtcgtttt ggaataatta ttatgtgaat aattcatgtt atttattttc
    22381 ttttcaccca tttttcccct ccaagtttta ctattgtaaa ttattaaata caactatatc
    22441 atataaaact taattatacc ttaattggat atatttatct attttatttg tttattgctg
    22501 ttgtttttta acaggtcttg atatttaaat atcttgttaa tgctaacttt attatttaca
    22561 ttttattatg cttaatttaa atttatttta ttctttattt tcagtagcaa actatcttta
    22621 aatcttaatt ataataaagt attaaccaat aaagttattc aacattagct aataaatttt
    22681 atccattaca attttagatt gttacacaca atatattttg atataatcaa attataaaca
    22741 aagtattcca agtatctaaa gacataaagg aatacttatt tttatgcttt atttttaatg
    22801 gaggcttata tgaacttaga aaaaattaaa aaattttggg gatttcctct agataaaaaa
    22861 cataaagaaa atgttgaaaa agaactttgc aattatcttt accatactgg taaaatcatt
    22921 tgcataataa tagtaatatc tcaaataatt atgatgatat caatctccgc tagagaggga
    22981 ggtccttttg ccacaccaag acgccaatgg tatttttata tgtatgtaac actattttgt
    23041 gtatcttctg tctttatgtt tgtattttct tatctttgga ataaaaaaaa ggattgttgt
    23101 actttttata taaatttatg gataatttat gtaacttttt tctgcctatg gggttgtgta
    23161 attactctac ttgaccagtt aggtggaaat gacctaagtg tatttagtta cattatgcta
    23221 gcagctgcag ctttctcagt attaaaatta ggagaatcag taatagtttt tggaggatgt
    23281 tttttgtttc ttaatttttt cttacctggt attcaaacta taccaggcaa tgagtttagt
    23341 aatatcgtca acacattttt tataacatcc cttgccgttt ttgtttctac aatgctatat
    23401 agaagtcgtg tatttactta ctatgacaaa cttttaatta gtcaacaata tgaagaaata
    23461 tatcatataa ataatttact taacgacaaa gtcatgacag atgaccttac taaaatgaat
    23521 aatcgtagat accttgaaga tattctacaa aaaaaattaa tcagccatgc aaatcaagaa
    23581 cctataactg gaatgatgat agatatagat tatttcaaac aatttaatga caattatgga
    23641 catcaaaagg gagactattg tttacaaaat attgccaaag taattttgga ttttacaagt
    23701 tctgaaaatg aacatgctat acgatatggt ggtgaggaat tttttatatg tatttttaac
    23761 tgtgatgagg aagatgctaa acttaaatca gaatgtttac gaaaaattat agagacctgt
    23821 aattttgagc gtgacgatat ccctttaaaa tgtgtaactg ttagtatcgg agtctacaca
    23881 aataaaattg aaaggacaat aacgctaaat gagtttataa gtaattgtga taaggctcta
    23941 tatactgcaa aagaacaggg acgtaattgt gttgcatttt attaaaaagt tacatactat
    24001 tacataaacc tataagtatt atattgcaaa ataaaagtaa ccaaattata tatttatagt
    24061 acaataaaaa taacttgcat atctctaaaa tagataaata tgcaagtcat tttagtgttt
    24121 acacttaaaa ttatataagt tttattatat ataattatta aaattcagca tttttaggag
    24181 ttcttgggaa aggtataacg tctcttatgt tagacatacc tgtcatatac ataattattc
    24241 tttcaaatcc aagaccaaat ccagagtggg tagcagtacc aaattttcta agttctaaat
    24301 accaccaata atcttcttct cttaatccca tttcattgat tctatctagt aatacatctt
    24361 ctctttcttc tctttgagaa cctcctacga tttctccaac tccaggaact aataagtcca
    24421 ttgctctaac agttttacca tcttcattca ttctcatata gaaagctttt atatcttttg
    24481 gataatctgt aacaaacact ggacaattat atatttgctc cgttatatat ctttcatgtt
    24541 cagtttgaag gtcacatccc cactcaacag gatactcaaa gtcatgacca gattcaatta
    24601 ataattccac tgctttagtg tatgttattc taacaaactc agagtttact atcttattta
    24661 atctttctaa caatccttta tctataaaac tattaaaaaa ttccatttct tcaggagcat
    24721 tttctaaaac atagcttata acatatttta tcatatcttc tgcaagttcc atgttatctt
    24781 caaggtctgc aaaaactatt tctggctcta tcatccaaaa ttctgaagca tgtcttcctg
    24841 tataagagtt ttcagctcta aatgtaggtc caaaagtata aacatttcta aaagaaagtg
    24901 ccattatttc ggcatttaat tgaccactaa ctgttaaatt agcctctttt ccaaagaaat
    24961 cttgagtata gtctattttg ccatcttctg tttttggaat atcatttaaa tccatagttg
    25021 ttattctaaa catttctcct gcaccttcac agtcactacc tgttatgatt ggagaatgtg
    25081 catatacaaa gtttctctct tggaaaaatt tgtgtattgc atatgcagct attgatctta
    25141 ctctaaatac agctgaaaaa gtattacttc ttggtcttaa atgtgctatc gttcttaaat
    25201 attcaagtgt atgtctcttc ttttgtagcg gatatgaact atctgattcg ccttctacaa
    25261 ctatgctttt tgcatgtatt tctactggct gtttagctcc ttctgtagat actaattctc
    25321 cctctacaag tatagatgag cttattgcta attttcctac ctctttaaaa ttttctactt
    25381 tctcatcaaa tactatctgc atatttttaa agaagcttcc atcatttagc tctataaatc
    25441 caaaattttt agatactcta gacgttctta tccatccagc tacttttaca gtcttcccta
    25501 tgtactgttc tttttctcta tacaattctt ttactgttat aaattccttt tgcattttaa
    25561 atcctcctag tataattgtt attaatttct tttaaatata gtttcaataa aaaaagccct
    25621 tcatccctat ataaagggac gaaagactat tactctcgcg gtaccaccct agttgtcata
    25681 atgacctctt agttaagcaa tgcttaaagc ctataacggt gccttccgtc taagtctact
    25741 tactaaataa gctttcgatt agaaactcca agatgttctt caatataaac ctcgtattga
    25801 gctttcacca tcctcaactc gctagaacta cattttatat ctactcttct cttcatagta
    25861 tttatctttt attatttctg ctaattaaca aaattatacc aatttataaa tttttagtca
    25921 ataaatttat ataattgata ctgattgcta tttaaaatat aataactcta ccttgcaaaa
    25981 tgacaataaa cacttatctt tactacttca gtttcaaaac ttttataatt tacttccatt
    26041 atcaacccag tcttttgctt ctgtaacacc cttaattgaa ggtattgaaa ctttactatg
    26101 aggttttaat ttttcaacat cagcccatgc tgctgtcgac tcatttccaa ctaaaagtga
    26161 acttttaagt cttttattat ctttaccttt taatgctctt gcttttttat tttccaaaac
    26221 tatcacctct attatttatt ttgtaatagt tttagcaatt tttcaaataa aattcataag
    26281 ttaaaattat aatgattttt aagtcaataa catatctttt ttatactaaa tctataatta
    26341 ttttt
//
LOCUS       DAMKOJ010000050        25885 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000050 DAMKOJ010000000
VERSION     DAMKOJ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25885
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.052"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            89..1378
                     /locus_tag="PC592_002310"
     CDS             89..1378
                     /locus_tag="PC592_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF4056273.1"
                     /translation="MRELLNVTLIIILVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIISIFNLSESIVYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLVVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRILVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            1407..2087
                     /locus_tag="PC592_002311"
     CDS             1407..2087
                     /locus_tag="PC592_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDF4056274.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWIETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTNIYDSSVPIIDLYDEKTKNMIEFMDREGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     SSKECHNL"
     gene            2188..2727
                     /locus_tag="PC592_002312"
     CDS             2188..2727
                     /locus_tag="PC592_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF4056275.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKEGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFTLLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSIYWTILTFIGVRYFQVYIVDSLYSLIIPYWPILVIILLATLF
                     VDEVLTIKFLRGNKDIVER"
     gene            2903..3922
                     /locus_tag="PC592_002313"
     CDS             2903..3922
                     /locus_tag="PC592_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF4056276.1"
                     /translation="MMGKVRFGIVGTSNIANIFLKAASKVKDFELVAIYSRNLEKARE
                     FGMSHGASIFFDDLEQMAKSKDIDAVYIASPNALHSRQAIICLKHKKHVLCEKSLASN
                     LKEVKLMIKTAKDNNVLLMEAMRITCVPNFRAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKSVKAVSHVLQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSYENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            4212..5402
                     /gene="dltD"
                     /locus_tag="PC592_002314"
     CDS             4212..5402
                     /gene="dltD"
                     /locus_tag="PC592_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDF4056277.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTLLEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKSPINWSHERKKAIEDAKKRVGKNPLNIDNYYYK
                     QHFKDGIDQYKGRDKDVNLLTSKEFESYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQNIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            5523..7037
                     /locus_tag="PC592_002315"
     CDS             5523..7037
                     /locus_tag="PC592_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HDF4056278.1"
                     /translation="MKIIEGIKKYSNTDRIALICNGDKLSYKDLNEYSDAISIFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLKDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPKLESMIFIGEALSKNLT
                     KELMSRFPNTRVINGYGPTEATVGVSVNDMTQKAIEDEKSLPVGYPMSNCKIKILDEA
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGIKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNVVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            7037..8185
                     /gene="dltB"
                     /locus_tag="PC592_002316"
     CDS             7037..8185
                     /gene="dltB"
                     /locus_tag="PC592_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDF4056279.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYVYWSFLFISMLPIIINKISP
                     VTSFGMIGFIGISYLNFRAIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSIIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKEKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            8204..8434
                     /gene="dltC"
                     /locus_tag="PC592_002317"
     CDS             8204..8434
                     /gene="dltC"
                     /locus_tag="PC592_002317"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDF4056280.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            8649..9434
                     /locus_tag="PC592_002318"
     CDS             8649..9434
                     /locus_tag="PC592_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF4056281.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNSTNLDKKQSIAKYASKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASLYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            9724..11634
                     /gene="phnW"
                     /locus_tag="PC592_002319"
     CDS             9724..11634
                     /gene="phnW"
                     /locus_tag="PC592_002319"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDF4056282.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPIEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVIETIEKLRENGLKIGSTTGYTREMMDIVQPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTE
                     EEVENMDKEELKIKMNTVSKKFKEAGAHFVIETMAELEDVLVKIENKTIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNDLVQDVRRRLISLGTKNTDKYTSVLMQ
                     GSGTFSVEATIGSTIPENGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDVEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKVYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEELSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKANGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIERFINR"
     gene            11923..12744
                     /locus_tag="PC592_002320"
     CDS             11923..12744
                     /locus_tag="PC592_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056283.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNIAGTGKIEGSVKCSKFNSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGDINSVEIDTSGIINVEG
                     SIKSDIIRGEGYLKANENIDCENINLSGIMECNGFLNCEEVNISLNGISNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYIESKLFANIIEADEIS
                     LENSEVKVVRGKNVKIGKGCYVESLEYSEIIEIDEDSIVGEIKNINEKVKLKKDK"
     gene            12785..13552
                     /locus_tag="PC592_002321"
     CDS             12785..13552
                     /locus_tag="PC592_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HDF4056284.1"
                     /translation="MEKGSIKILGEGFISSGEYESIRIVGSAKSKGNIKSDEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLSIYGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVSENMYAQDIKIYGEMRNKSNIECEDIKVYGVIECDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDVFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSIFLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            13560..14180
                     /locus_tag="PC592_002322"
     CDS             13560..14180
                     /locus_tag="PC592_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HDF4056285.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSTITFEELKLIVNIIEENFTSIYNENGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(14482..15069)
                     /locus_tag="PC592_002323"
     CDS             complement(14482..15069)
                     /locus_tag="PC592_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF4056286.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENINISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHVGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(15155..15592)
                     /locus_tag="PC592_002324"
     CDS             complement(15155..15592)
                     /locus_tag="PC592_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4056287.1"
                     /translation="MEDKYIVHFISKTKTNMIKFIENKLSKNDLDELIPTHGNILTAL
                     YENNGILTMKEIATKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            15696..16694
                     /locus_tag="PC592_002325"
     CDS             15696..16694
                     /locus_tag="PC592_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HDF4056288.1"
                     /translation="MNKKFKSLYITEEEGNFKRNIVERDVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVRLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKDMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKQALLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGTHVGRTVVDLEKI"
     gene            complement(16815..17741)
                     /locus_tag="PC592_002326"
     CDS             complement(16815..17741)
                     /locus_tag="PC592_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF4056289.1"
                     /translation="MNKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMKGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSIGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            18127..19728
                     /locus_tag="PC592_002327"
     CDS             18127..19728
                     /locus_tag="PC592_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4056290.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKNVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETYDPEGGHIGRVEGSEEPNGYLEENAFFNVSSKIKPPSSNEIFNSIEKAQDIYLS
                     YGITTAQEGLMEENQFNLLKAMANQNKLKIDVVGYVNLKKSKPVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSKPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAAEQLIDVFEKVLTLKEQSSNNMRPVMIHAQTVREDQIDDMKRINMIPSYF
                     VAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAVN
                     RITKKGVQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPLT
                     IDPMKIKDIKVLQTIREGEVLYSLK"
     gene            20515..21786
                     /gene="serS"
                     /locus_tag="PC592_002328"
     CDS             20515..21786
                     /gene="serS"
                     /locus_tag="PC592_002328"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF4056291.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKAFNLDEVVKLDDERRKILQE
                     VEVMKNKLNTASKNIPNLIKEGKDVENEKIKLKDLSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPGVPQGETDDDNVEVRSWGETTKFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYAHTLNGSGLAIGRS
                     VAAILENYQQEDGSVIVPEVLRPYMGVSVIK"
     gene            22059..23564
                     /locus_tag="PC592_002329"
     CDS             22059..23564
                     /locus_tag="PC592_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF4056292.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELVVSNIV
                     NNFETSEILEFNKNNKIENTPVNYSENTLNLYAAVESIRGQFIDPFKIPLIIYDDYWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSANQFTCKYGITIYNISIIYKNNSIGV
                     IRGGYILMSDSSLGVGHRNLYDIPEGAARTMKRLLNQIAKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMVSIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIENYLNLQKLRYGDALKVKYLIPKKLYNLSVP
                     FNFIQPIVENAFTHGSRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDKNNIDKIKAG
                     IRINNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPSENYKEYV"
     gene            23678..24376
                     /locus_tag="PC592_002330"
     CDS             23678..24376
                     /locus_tag="PC592_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF4056293.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     TGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFDYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIK
                     KGMTPKVYKLNTKN"
     gene            24660..25748
                     /locus_tag="PC592_002331"
     CDS             24660..25748
                     /locus_tag="PC592_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056294.1"
                     /translation="MSDKVNIKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     VGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIISGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNIAPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCREKSTQGQE"
BASE COUNT        10254 a         2652 c         4436 g         8543 t
ORIGIN      
        1 agaatatata ttataaatta aatttataaa tataaggggg gaactttgag ttcttataga
       61 tttcttacac tataagaacc aatactttat gcgggagtta ttaaatgtaa cacttataat
      121 aatacttgtt ttgataaatg ctttttttgt agcttgtgaa tttgctatgg taaaacttcg
      181 tagttctagg attgacacca tgataactga aggtaataat aatgcaaaaa gatgtaaaat
      241 aataaaagac aacttaaatt cctatctttc tgcatgtcaa cttggtataa cactttgttc
      301 acttgcatta ggttggatgg gggaatctac agttaaagag ttgattttac caataataag
      361 catatttaat cttagtgaaa gtattgtata tactatatca atttccattt cttttttaat
      421 tataacaatg atggaggttg taataggaga attggttcct aaagctttag cactttataa
      481 tacagaaaaa ataatgttga gtacatcttt tttagtagta ggattttata agttaacata
      541 tccaataata tattttttca acttaagtac tgatttattt cttaaaccat ttggatattc
      601 acaagctgat gaagttgatg aaccacatac aggtgatgaa ataagaatac tagtggaaga
      661 aagttataaa agtgggctta tagatgaatc agagcaaaga ttagttgata atatttttga
      721 atttgaggaa aagaaaatta gagagataat ggttcctaga accgatatgg tatgtatata
      781 tgaaagtgac tctgaagaaa agatattagc tattttaaaa gaagaaggtg ttacaagata
      841 tccagtatgt agaaaaaaca aagatgatat attaggtttt gtacatataa gagatttata
      901 caatcaaaag ataaatgaaa ataaaattga actagaagag atattgagag atattatata
      961 tatttctgaa aatttgacta tagataaagc tcttgagagg ataagaaagg aaaaacttca
     1021 acttgctata gttgtggacg aatatggtgg tacatctggt gtggtaacga tagaagatat
     1081 actagaagag atagttggag aaattcaaga tgaatttgac aaagaagaga ctcatattaa
     1141 gaaaatagga gcaggttctt acttagttga tggaactgaa tccattaact atattaataa
     1201 gtattttgga cttgacatag agcatgatgg atttgacagt ataggtgggt ggatatcata
     1261 tatgcttggt tcaaatatta aagtaaatca aagtgtaact tttgaaaatt acaatttcac
     1321 aatattagag ttggataaat tgagggttgt aaaattaatc ataaaaagtg taatataatt
     1381 atatcaaaaa atattggagg aattgtatgc aaaaagtaga aggaattatt tttgacatgg
     1441 atggagtttt atttgactca gagagaattt ctcttgaatt ttggatagag acgtttgaaa
     1501 agtatggata tactatgact aaggaaatct atacatcagt tatgggaaga aatcgtaaag
     1561 gtataataga aggtctcaca aatatatacg atagttctgt accaataata gatttgtatg
     1621 atgaaaaaac taaaaatatg attgaattta tggataggga gggagctcct atcaaattag
     1681 gagtcaatga actaatctct tttttaaagg aaaatggata caaaatggct gttgcaacat
     1741 caacaaagag agaaagagca gtaaagagat tagctaaggc aaatttaaaa gattactttg
     1801 atgctatagt ttgtggggat gatgttgtaa actctaaacc aaatcctgag atattcttaa
     1861 aagcagctaa aaagataaat gttaatcccc aaaattgtat tgtgatagag gattcgccta
     1921 tgggagttga agctgcatac aatggtggta taagatgtat aaatgtacca gatttaaaag
     1981 agccagatga gcaaattaaa tcacaatcac ataagatact tgaaaattta ttagaagtta
     2041 gagaatactt aaaaagtttg agctctaaag aatgtcacaa tctataatat aaaatattaa
     2101 ttaaataaat taaatataat ttctttgatt tagaataaat ccatgaatat gagaaaaaat
     2161 aagtataaac agctaggagg aatattcatg gataatgtag gttctctatt atatttttta
     2221 tttaattttt tcttgtatgg ttttataggt tggataattg aaaatttata tagttattat
     2281 aaagaaggac attttcaaga agatggattt ttaaatggtc catttaaacc aatgtatgca
     2341 attgcaatgt cgattataat agaggtatca agatttattg acccaaataa tatatttaca
     2401 ttgcttttat tatgtctagt agtgccaaca gtagtagaat atattacagg aatacttatg
     2461 aaagtatatt ttaataaggt ctattgggat tattcagatt ataagtacaa tagtagagga
     2521 atagtatgtc taaagttctc tatatattgg actatattga cctttattgg agttaggtat
     2581 tttcaagtat atatagttga tagtttatat agtcttataa taccttattg gccaattctt
     2641 gtaattatac ttttagcaac tttgtttgtg gatgaagttc ttactataaa atttttgagg
     2701 ggaaataaag atatagtaga aagataactt taaaaatata agttgaattt agattgtagt
     2761 taaaagaaag ctatgttaaa atggtgaaat catttaaaat tagctttctt ttttatttga
     2821 taaaattatt ttataatata gctataagtt gtaaagtttt ctattaaaat taaaataaag
     2881 tgtagaaaat ggggagtgat ttatgatggg taaagtaaga tttggtattg ttgggacaag
     2941 caatatagca aatatatttc taaaagctgc atctaaggtt aaagactttg aattggttgc
     3001 tatatattct agaaatttag aaaaagctag agaatttgga atgtcacatg gagcaagtat
     3061 tttttttgat gatttagaac aaatggctaa atcgaaggat atagatgctg tatatatagc
     3121 ttctccaaat gcattacatt caaggcaagc cattatttgt ttaaaacaca aaaaacatgt
     3181 actttgtgaa aaatcgttag catctaattt aaaagaagtc aaattaatga taaaaacagc
     3241 caaagataat aatgtattgc ttatggaagc tatgagaatt acatgtgttc caaactttag
     3301 agcagttaaa gaaaacttgt ataaaatagg gaaaataaga agattttttg gaagctattg
     3361 tcagtattct tccagatatg ataaatataa aaatggaatt atagagaatg catttaaaaa
     3421 agagttatca aatggagctt taatggatat aggagtgtat tgtatacatc ctatggtaaa
     3481 tttatttggg gctcccaaat ctgtaaaggc tgtttctcat gtacttcaaa ctggagtgga
     3541 cggagaaggt tcagctgtat ttcaatatga tgatatggat gctataattc agtattctaa
     3601 agtagctgat tcttatatac catctgaaat acaaggagaa gagggaagta taataattga
     3661 aaagcttaat ctatttgaaa aagctattat taaatacaga gatggaagag aagaagatat
     3721 atctattcca aaagaaaaag cagaggaaaa acctagagaa atagaaggaa tgtattatga
     3781 acttgtagag tttataagtc ttataaataa caataaaata gaatcaaata taaattctta
     3841 tgaaaactca ataatagtaa tggaaattat ggatgagata agaagacaaa gtagtattgt
     3901 ttatccagct gatagtatat agtttatatt ataaagtata taagaattta taatatatat
     3961 tcttaaataa atttaatttt aagttaaggt aagatgtata cttagttaag tgttaaaatg
     4021 tcaaattata agtatgaaaa agtgctaaaa agaaatttat ttttggcgct ttttttcttt
     4081 tttttacaat tttgtaacag tatcaaaaaa agttttgacg attttattac aattttgtag
     4141 ttgaatatac atatcaaaac taatatgatt aataataaca taaatttgaa tatttttaga
     4201 ggagagaaaa tatgagaaaa ttgatatact ttattacacc ttttataata ggcgtagtat
     4261 ttttatttgg actagacaaa tttcttgatt ctaaaactga tgaacttttg agggagaaaa
     4321 atctacttcc aattatggat gatactttaa gtgatataaa agataaagga gttacagcaa
     4381 ataatcattt tttaagagaa aaagatatta tgattttggg gtcatcagaa cttagtaatt
     4441 caacaaaaca acatccaaag tactatttta atacgaatag gagtaaaaat aaggtgtttg
     4501 caattgggag agcatatact cagacattac aagatgctgc aatattagga agtatgaatc
     4561 ctaatattga taataagaaa gttgtcttgt taatttctat gcaatggttt atggaaaaag
     4621 atggagtcac aagtcaccat tatcagtcta gattttcacc aatacaattt tatcgatttt
     4681 tagataatcc aaaaatatct aaacaaaata agattgagta tgcaaaaaaa tcaagtaagt
     4741 tattatgggg aagtgacgag tataaagcag aagcattata tgctaagcta tatgagccta
     4801 agacgttgct tgaaaaagct gaaaaggtgc ttttagagcc ttattttcaa ggaagaaagt
     4861 actgtatagc tcttaaagaa aagggtattc tttataaacg attaattaag ctagataaaa
     4921 agagagcaac aaaaagaaaa agcccaataa attggtcgca tgagagaaag aaagccattg
     4981 aagatgctaa aaaaagagtt ggtaaaaatc cactaaatat tgataattat tattataaac
     5041 agcattttaa agatggtata gatcaataca aaggaagaga caaagatgta aatttattaa
     5101 catctaagga gtttgaaagt tataaactta tgctaaatgt ttgtactgac ttaggtatta
     5161 agccagttgt tgtattaatc ccaagtatgg ataaattcta taatttgact ggtatttctg
     5221 aaaaagaaag aaatcaatac tacgataaag cacaaaacat agcagaaagc aaaggctttg
     5281 aggttctaaa tcttaaagat aaagggtcag ataagtatta tttaagggat gtaatgcatc
     5341 ttggcacgaa aggatgggta gatgtctgtg agagattatt taaaatattt aaagaacaat
     5401 aaggatttgt taactagtat ttgtttaact atggttataa tattggcgat aggagttcta
     5461 acatttactc catttaaaga attgccattt atttataacg gattttaaag gagcattctt
     5521 atatgaaaat tattgaagga ataaagaaat attcaaatac agatagaata gcactaatat
     5581 gtaatggaga taaactttct tataaagatt taaatgagta ttcagatgct atatcaatat
     5641 ttttaaaaga tgtatacaaa gaagaagata ctcctatagt aatttatgga aataaagaaa
     5701 atatgataat ggcatgtatg ataggagctt taaaatcagg gagagcgtat gtgcctcttg
     5761 atattagttt tccaattgat agagtttttg aagtcactaa agagataaaa ccaaaagtat
     5821 tatttaattt tagtgatgaa aaagattttg gagatattaa tgtaattgat atggataaac
     5881 taaaggatat aataaatgaa tatcagggaa aatcactaga taaagaaaac tgggtaaaag
     5941 atgatgaaaa tgcatatata ttatttacct caggaagtac aggaaaacca aaaggggttc
     6001 aaataagttc aaacaatttg gatagctttt cggattggat aagcccatat ctaaacatag
     6061 atggaagtga aaaagtaata atgaatcaac cagcatattc ttttgacctt tcagttacaa
     6121 caatatatcc tggtcttatc catggagcta cattattttc aatatcaaaa gatgtattgg
     6181 cagactataa agaactattt agacaattta gtatatcaga tatagctgta tgggtgtcaa
     6241 ctccttcttt tgcaggggta tgtataactg aaaaagagtt caatagtaaa atgcttccta
     6301 agcttgaatc aatgatattc ataggagaag cactttcaaa aaatcttact aaagaactta
     6361 tgagcagatt tccaaacaca agagttatca atggatatgg accaacagag gctactgttg
     6421 gtgtgagcgt aaatgatatg actcaaaaag ctatagagga tgaaaaaagt cttccagttg
     6481 gatatcctat gtcaaattgt aaaataaaaa tacttgatga agctggaaat gaacttaaag
     6541 aaaatgaaaa gggtgagatt ataataattg gaccatcagt ttctaaaggt tacttcaata
     6601 ataaagaaaa gactgatgaa gtatttttct atgatgaaat agatggtata aagtggagag
     6661 cttataaaac tggagatatg ggatatcttt tagatggaaa tatatattat tgtggaagaa
     6721 aagattttca gattaaatta aatggattta gaattgaaat agaagatata gaaaataatt
     6781 tgagaaaagt acataatgta aaaaatgtag tggttttacc agtatataag gacgaaaaaa
     6841 ttgcttactt aaaaggtatt gttgagttaa atgaaaagaa tgatttaagt aatattaaaa
     6901 atgggatgat aataaaaaag gaacttggaa agtatatacc ttcatatatg attccaagaa
     6961 atatttcaat aatctctgaa tttccaacaa atatcaacgg taaaatagac agaaagaaac
     7021 ttatggagga aatttaatga ttttttcaca gtatggagat tatttttatc tttatatatt
     7081 attattaaca tcaataccag cagtaatttt aggtctaatg ggtaagaata taaagtatta
     7141 tggtatgttg gcaagtttgt ttatgatatt cctaatagta ggaattgatg tccaactaaa
     7201 gtacttagta atatttatta ttcttgaagt aataatagtt aaaggatatg aatatgtaag
     7261 aagaaaaact aaaaataaat acgtatattg gagctttttg tttatatcaa tgcttccaat
     7321 cataatcaat aaaatatctc cagttacttc ttttggaatg attggattta ttggaatatc
     7381 atacttaaat ttcagagcta tacagatggt tattgaaatt tatgatggtg ctataaaaga
     7441 agttaaaatt tcaaagatgc tttattttat gttatttttt ccaactttaa gttctggacc
     7501 tattgatagg tcaagaagat ttgaacaaga cttggaaaaa caaatttcta gaaaagagta
     7561 tatagaagaa tatttactgc caggaataaa aaatattgtc atgggagtag gttataagtt
     7621 tgttatagca tttttgataa atacatattg ggtatcaata atacctaaag atatgagttt
     7681 tataaatatt ttaagttata tgtacgcata tagcttgtat ctattctttg attttgcagg
     7741 atatagttta tttgctatag gtacaggtta catatttgga atacaagtac ctataaactt
     7801 tgacaagcca tttatcagta aagatatgaa agagttctgg acaagatggc atataagcct
     7861 ttcaagatgg tttggagatt atattttttc tagatttgtt atgtcatcaa tgagaaagaa
     7921 gagatttaag aaaagaacta ctgctgctca tgtggctcag atgataacta tgataacaat
     7981 gggattttgg catgggctaa cttggtacta cgttgcttat ggtgtatatc aaggtttggc
     8041 acttgttcta actgatatat atcagagaaa atccaaattt tataaaaaac ataaaaaaga
     8101 aaaatggttt gagagagtac agattttcat tacattccac attgtatgtt ttggattact
     8161 gatattctca ggttatttag cttaacttta aggaggaaaa attatgcaag agacagttat
     8221 agaaatattt gaagatgtat tagggactga tgagataaga gaagatttag accttaactt
     8281 atttgagaca gagcttttag actcattagc tataattgaa gttttacttg aaattgaaaa
     8341 tagattagga atagagcttc aaccaactga tttagagaga aaagatatgt ctactgtaaa
     8401 taatttagta aaattcttgg aaacaagaaa ataaattagt agttagatta aatattaatt
     8461 tataaaataa aattttacaa agtccatctg atactaatat ttgatggact tttttaatga
     8521 taatacatag tcttttgaag acaactttaa ttaagtaaaa aatttaatat ataaatatga
     8581 ttttgtaaat cttaggtatc attgtaatat tataggagaa aaatatatta tatttaggag
     8641 gaaaatgaat gtctttaaat tcaatagata gaaaaaaaga aatactgaaa ttattagatt
     8701 caaaaggtaa ggtaaatact aaagagttag taaaaagact agaagtatca tcagaaacaa
     8761 taagaagata tttggaagaa ttagaaaatg aaaataaatt aaaaaaggta tatggtggtg
     8821 ctataaaaat aaattatggg gtgattgaac cagaacatat aaagagaaat agtactaatt
     8881 tagataaaaa acaaagtatt gctaaatatg catctaagtt tgtgaatgac aatgagtcaa
     8941 tcatcataga tgaaggtact accaatttgc aaattgtaga ttatataata tctgtaaaca
     9001 atttaaaaat tattacaaat tcttatccag ttctatcaaa attgatttct tatgaaaatc
     9061 aaggcttatt tgatggggaa gttatattta ttggtggaaa ggtaaattta aaacatcaaa
     9121 gaacagcgtg tccaatgtca atagatacta tgaagaactt atacgtagat aaagctttta
     9181 tatctagcga aggtatactt gatagttttg gaattagtag tatagaccaa aataaggcat
     9241 tgttgtcaaa agaatatata aaaaattcaa aggaaagttt tgtattgtgt gatagttcta
     9301 aaatcggaat tgctagtctg tataagatag cagatttaga ggaattagat tttgttattt
     9361 gtgatgtaga gcctccgaat gaatggaagg ataagttaaa tgagataaat ataacatgga
     9421 tagaagcaaa ataaaccctt agttttatag aatacaacta tgcttaatac aaccaaattc
     9481 ataaaatata gtcagtttat agattaatat tagaaagtaa attttagatt gtaaatttag
     9541 aattttatag aaatatgaca tagaataaaa acaacttaaa acaaataaaa acaactaaaa
     9601 acagaaattt aatatatatt taacttaaat atgatgtata attaacatat gaaagttata
     9661 ctttaaaagt aaaaacaatt aaaaacacaa aaattctaaa aagaatctat ggaggctata
     9721 aatatgaaaa agatatatgg agaaaaaata aaagcagtag tattcgattg ggctggaaca
     9781 acagtagatt atggatgttt tgcacctctt aatgtattta tagagatatt taaaagaaga
     9841 ggcatagatg taacaatgga agaagcaaga aaacctatgg gaaaattaaa aatagaccat
     9901 ataagagaaa tgtgtgaaat ggatagaata aaaaatcttt ggtcagataa gtttggtaaa
     9961 gtgccaattg aagacgacgt aaatgaactt tatgctgaat ttgagccaat gttatttgag
    10021 acattagaag agtatactac tccaatcccc catgttattg aaactattga aaaattaaga
    10081 gaaaatggat taaaaatagg ctctacaaca ggttatacaa gagagatgat ggatatagtt
    10141 caaccaaacg ctgcaaaaaa aggatactca ccagattttc ttgtaacacc atcagaagta
    10201 tcacaaggaa gaccatatcc ttggatgtgc tataaaaatg ctgaagcttt aggagtatct
    10261 cctatgagtt ctatggtaaa agtaggagat acaataagtg acgtaaaaga aggcgtaaat
    10321 gcaggaatgt ggagtgttgc tgtaataaag ggttcaagtg agttagggct tacagaagaa
    10381 gaagtagaga acatggataa ggaagaatta aaaattaaaa tgaatacagt ttcaaagaaa
    10441 tttaaagaag caggtgcaca ttttgtaata gaaactatgg ctgaattaga agatgtattg
    10501 gtaaagatag aaaataaaac tattaaatca gactttgtac cagaaaatga ttacatatta
    10561 cttacaccag ggccactatc tactactaaa tcggtaagag catctatgtt aaaagattgg
    10621 tgtacttggg atgttgaata taatgactta gtacaagatg ttagaagaag attaatttct
    10681 ttaggaacaa agaatacaga caaatacaca agtgtattaa tgcaaggaag tggtactttt
    10741 tcagttgaag ctacaatagg tagtactatt ccagagaatg gtaaacttct tgtaattgca
    10801 aatggagcat atggaaagag aatgaaagat atatgtaatt atcttaacat agaatttgtt
    10861 gattgcacat ttaaagatgt agaagcggtg gatttaaatg tagtagaaaa tttattaaaa
    10921 gaaaataaag atataacaca tatatcaatg gttcactgtg aaactactac agggagatta
    10981 aaccccatac aagaggtagg gaaacttgca aaagaatata acaaagttta tatagttgat
    11041 gctatgagta gttttggggg aattgagatt gatgttgaag attttaatat agatttttta
    11101 gttagtagtt ctaacaaatg tatacaagga gtacctggat ttggttttat aatagctaat
    11161 aaagaagaat tatctaaatg taaaggtata gctaaatcat tatctcttga tgtatatgcg
    11221 caatgggaga ctatggagaa aaataatggt aaatggagat ttacttcacc tacacatgtt
    11281 gtaagagctt tttatcaagc tttattagaa ttagaagaag aaggttctgt tgaaaaaaga
    11341 tatgctagat ataaagaaaa tcaatttaca atagcttcaa gattaaaatc tttaggtttt
    11401 gatactttag tgaatgataa tgctcaatca cctgtaataa caactttctt atatcctaaa
    11461 aatgcaaagt ttgaatttat ggaattttat acttatttaa aagctaatgg atttgttatc
    11521 tatccaggta aattgactga tatagataca tttagaatag gtagcatagg tgaagtttat
    11581 ccaactgata tggagagact agcagatgta atagaaagat ttatcaatag atagaagaag
    11641 atagtggctt gtaggttact atagaattta aagacttata ttttagatgt ttataaaatg
    11701 aatatataaa gattgagtaa tagggatata ttttacttaa accacaatct aagaaattag
    11761 atttatagtt tagataaagt atttttccta ttattttttg tgtttattta tataaaataa
    11821 attatggtta ttttattaag tattattatc atacttgaca acgtaacaat gttttgttat
    11881 attaagctta gagataaaat acggtaaaga aaggatatca ttatgaatga agaattaagt
    11941 tcactaagat ttgatggcgt tggaaaatgt aaaggtggaa tttttgataa tgttaatata
    12001 gcaggaacag gaaaaataga aggaagtgta aaatgtagta aatttaattc ttctggttca
    12061 gcaaaagtgt ttggtacaac agaatgtaat gaatttttta catctggttt aagtaaagta
    12121 gaaggaaata tactggcatc aaaagttgag atatcggggc ttcttagatg tacaggagat
    12181 attaattctg ttgaaattga cactagtgga attattaatg tagaaggaag tataaagtcg
    12241 gatattattc gtggagaagg atatttaaaa gcaaatgaga atatagattg tgaaaatatc
    12301 aatttaagtg gaatcatgga atgtaatgga tttttgaatt gtgaagaggt taatattagt
    12361 ttaaatggaa tttctaattt taatgaagtt ggagcaagta gtataaatat aaaaaaaggt
    12421 catggagatt attgcaaaaa atttcgtatg ctagaaaaaa agcatatcaa ctttgaaaag
    12481 gtatcttcaa atttaataag tttgggttta ttatcaatta gaaagtatat agaaagcaaa
    12541 ttatttgcaa atattataga agcagatgaa ataagcctag aaaatagtga agtcaaagtt
    12601 gtaagaggaa aaaatgttaa aataggtaag ggatgttatg tagaaagctt ggagtatagt
    12661 gaaattatag agattgatga agattcaata gttggtgaaa taaagaatat aaatgaaaaa
    12721 gtaaaattaa agaaggataa gtaataagta ggtttaaaaa taaaatttaa aatgaggtaa
    12781 taatatggaa aaagggtcta taaaaatact tggagaaggc tttataagta gtggtgagta
    12841 tgaaagtata agaatcgtgg gaagtgctaa atcaaaagga aatatcaaaa gtgatgaagt
    12901 aaaagtcctt ggagatgcaa aatttgaagg tgacatcaat ataaaaaatt ttgttgttaa
    12961 tggaaaaact attataagag gcaatcttaa agcagagcgt gtaagagtga atgggcaact
    13021 tagcatatat ggagatgctg aaatagatga cttagttata actgctcaac agaaagtgga
    13081 tggcaaactt aaatgtaata atgttacaat aagaggacaa ttaagtgtaa gtgaaaatat
    13141 gtatgcacaa gatataaaaa tctatggcga aatgagaaat aaatcaaata tagaatgtga
    13201 agatataaag gtatatggag taatagaatg tgatggcctt ttaaatggag aaaatatata
    13261 tgtttattca ggaggaggtt cttattgtaa agagataggt gcgactaata taaaaatagg
    13321 aagaagcaaa gatgtttttt cattaattaa aattattaat attttttcag gaaagtttaa
    13381 atgcaacttg atagagggag atactattga attagaagat gcatcaataa aagatatacg
    13441 aggtaaaagc atatttttag tagataattg tgatgttgga aatattgaat acagtgataa
    13501 tttgtcagtt tcagataatt ctactgtaaa aaacagtata aaggtgggct agaagagtta
    13561 tggaagaatt aatatctaag aaagatttat tgagcaaaac taatatatct tatgggcaat
    13621 tatatagatg gaaaagaaaa aacataatac cagaagaatg gtttataaag aaatctgctt
    13681 ttacaggtca agagactttc tttccaagag ataaaatact agaaagaata gagttaatat
    13741 tgtctatgaa agaagagact tctcttgatg acattgcaaa tatgtttatg aaaaaagata
    13801 ttaataaaga atttgatatt gattttattc ttagtaaaga agttatatgt aattacacca
    13861 aagaaatatt tcaaaattta tataagaaag agcaaagtat aggtaaaaaa gaacttctta
    13921 tattgagtat aatagagaag tttttagtta aatctacaat aacttttgaa gagttaaaat
    13981 tgatagtgaa tataatagaa gaaaatttta catcaatata taatgaaaat ggaaagattt
    14041 atttgtttag aaagtttgga gttccatttg tagttggatg tctggattat aaaaaagtaa
    14101 aatttgaaaa agatgtagtt aagattattg agattgactt aacaaaagaa ataaatgata
    14161 taagtataaa gttatcgtag tgtgtattat cttatataat gtattacaat aatctaccta
    14221 aaatacactt tatttaaata ttgggtttaa agatgagttt ttatgtgaat atgtaaaact
    14281 taaagataga tttaagcaat ctatagggat tagtaaacaa taaaatgaac catgatgaag
    14341 tactataaat tgtatttaaa ctacattttc tacttatagt aatatcaatg gttcatttta
    14401 tttttattaa gataatacag tatttataaa aatacttaat ataaatatag caaattgttt
    14461 aaataaaatg attatcttag tttattcaaa taatgagttt ttaaaatcta agaaatatcc
    14521 ttgtggatga agacatacag gacaagcttt tggagcttct ttacctacat gtatatgccc
    14581 acaatgtgta catatccatt gtatatcttc atttcttctg aataaagtac cttcttctaa
    14641 atcagtagca tatctaccaa atctatcacc atgaactttt tctatttcag ctatattttc
    14701 aaataactta gctatagatt caaatccttc ttcacgtgct gtttttccaa agtttttata
    14761 tacatcatcc cattcttgaa gctcattatg ttgtgcagct ttaagatgtt gtgctgtttt
    14821 atcatataaa tctacagggt atgcccctga tatatttatg ttttcaccag caaattcttt
    14881 tagtttagaa aagaattgtt ttgcatgtga tttttcttgg tcagcagtgt aattaaataa
    14941 agattctatt atatataatc cttctttttt tgctacagat gcagaaatat tgtatctatt
    15001 tctagcttga ctctcacctg caaaagctct caataagttt tctttagttt tactatcttt
    15061 taaattcata ttctacctct ctatcacaat aaatttttac aatatttgat tctttttatt
    15121 tattattcca atagaagata taattatgct taatttagtc agcattttta aaattatcat
    15181 taattttttt taaaattcta agaaattctt gtttttcatt ttctgtaata ttatggtatg
    15241 ctgtttcttt aacttgtgtt gagatactat taaatgtatc ttctatgagt agtgcttttt
    15301 ttgtaagctt tatatatgtg atacgtttgt cattggtaca tttttgtctt tctagatatc
    15361 ctagatttat gagtttatta accaacactg taacagtgga tttgtccttt cctattttag
    15421 ttgcaatttc tttcattgta agtattccat tattttcata aagtgcagtt aagatatttc
    15481 catgagtagg tatcaactca tctaaatcat ttttactgag tttattttca ataaatttaa
    15541 tcatattagt ctttgtttta cttatgaaat gtactatata tttatcttcc ataaattatt
    15601 ctccaatctt taatctattt aaattagttt gacataaaac tatttataaa ctataattag
    15661 tttaacataa aactaaatgt attgggagga aatttatgaa taaaaaattt aaatcactat
    15721 atattacaga agaggaagga aattttaaaa gaaatatagt tgaaagagat gtagatacat
    15781 tgccagaggg agaagtttta ataaaagtga aatattcttc tctaaattac aaggatgcac
    15841 tttctgccaa tggtaataag ggtgttacta gaaaataccc tcatacacca ggaattgatg
    15901 catctggtat agtagaatct agtagttgtg atgattttaa aattggagaa gaagttttag
    15961 taacaggtta tgacttggga atgaatactt ctggtggatt ttcagaatat ataagagttc
    16021 cttccagttg ggtagttaga cttcctaaaa atctttcact aaaagaagca atggattatg
    16081 gcacagcagg gtttacagca gctttatctg tgtacaaatt tatagattct gtagacaagg
    16141 acatgggaga tgtattagta actggtggta ctggaggagt tgctgtaatt gcaaccaaaa
    16201 tattgattaa attaggttat tcagttgtag tttcaacagg aaaactagaa gaacaaaaac
    16261 aagcattact aaacttaggt gttaaagatg ttatacatag gtcagaagtg gatgataact
    16321 caggaagacc tctacttaga ccaagatggg ctggagtaat agatacagta ggaggaaata
    16381 ccttagcaac agcaataaag acaactaatt attgtggagc agtaacaact tgtggtaatg
    16441 caggaggagt tgattttaca agttcagtat atccatttat cttaaaggga attaccttgt
    16501 atggtataga ttctgtggac tgcccaatga atttaagatt aaaaatatgg gatttattat
    16561 caaatgaatg gaaattagat gatttagacg atatggtaaa tgtggtatca ttagaagaat
    16621 taaatgacag tatagattca ataatggcag gaacacatgt gggaagaaca gtagttgatt
    16681 tagaaaaaat ataggtgact aagtttgcaa ttaggatttt gggttttaag caaaaatgag
    16741 atacttgtaa tttacttatg agtatctcat ttttttatgt aaaaaaattt tatgtagaag
    16801 tttgtgtaaa caggttattc atgaacgatt aattcaaata catctggtct tgaatagtgc
    16861 ccttctgaat caaaatctag tctgctaaga actatttttt ctaggtctaa atcagctatt
    16921 agcatttctt ctttattgaa aatagggcca gctacatatt ttccaaaagg gtcaactata
    16981 caactccctc ctggacacat aatttctggt tctgcatcta gttctttata gtaattaagg
    17041 tcagtaggat acatgttttt ttctacatat tgattacatc caattacaaa acatcttccc
    17101 tctaaagcaa tatgtttcat agttgcttgc cactcttctc ttgaatctgc agtaggggct
    17161 atataaagtt ttacaccctt agcataaaga gctgttctag ctaatggcat ataattttcc
    17221 caacaaatca atgaacccat ttttccatat ggagtatcaa ctactgtaag agtacttcca
    17281 tctccttctc cccatataca tctttctgtt cctgtaggtt taagttttct gtgtttacca
    17341 attagcttac cttctggaga gaaaaataag tttgtgcaat aaagggtaca atttatatca
    17401 ttaccatccc tctctgttat acctattgat agatatactc ctgcttcttg tgctgctttt
    17461 cctaataaat ctgttgtagc actaggaact ggtacagaat tatcatagta tcttttccaa
    17521 tcctctctac ctttcattgt tctacttcca acaacaaatc caaatgaaag acctcttgga
    17581 tatgcaggta tgaatgcctc agggaaaact acgatatttg ccccttttct accagcttct
    17641 ttaattaatc ccaatgcttt ttcaacagtt ttttctaaat ccattatgac tggtgatgcc
    17701 tggacaacag caattcttac atttttattt tccttgttca taaaaaacct cctaaaaaat
    17761 atttaaattt gttgcattga atagactaca tgagatgtta tttgagaacg aagatattta
    17821 tattgtgaat aataatataa ctgtatattt aaaataatac atcatgattt aaaaaattac
    17881 aattgtacat atataattga gtttagatat ttaaatttaa taacttataa tattttttca
    17941 attagtataa agcctattaa tttgtcttat ttacaatgaa tagtatttac ttcttggcaa
    18001 acaataatta aaaataaaac ttttatataa ttaaaatcta aagaaaaagt ttataaagaa
    18061 gataatataa ttaagtagaa aataaagaaa aaaatttatt aaagtagaca acataaggag
    18121 aattttatga aagaaaaaat ttattacaat ggaaatatca tcacaatgga agattcaata
    18181 tgtggagatg cgattcttat aaaagataag ataataaaaa agataggaac aaaagaagaa
    18241 gtatttgctt tgaaaaataa agatacagaa attatagatt tgcaaggtaa gacattgatg
    18301 ccatctttta tagactcaca tagccatttg atagcttttg ctactactct aaagttagtt
    18361 cctttagaag atgcaactag ttttaaagac atagtaaaaa aaatacagga tttcaaagag
    18421 tcaaataata taaaaaaagg agactggata attggatttt catatgataa taatttttta
    18481 gaagaaaata aacatccaga taagaatgta ctcgacagtg cgtcttcaga aaatccaata
    18541 ctaatttcgc atgcttctgg tcatatggga gttgcaaata cattggggtt aaaacagctt
    18601 ggtgttacta atgaaacata tgacccagaa ggtggacata taggtagagt agaaggcagt
    18661 gaagaaccaa atggatactt agaagaaaat gcatttttta atgtatcatc taaaataaaa
    18721 ccaccatcat caaatgagat ttttaattca attgaaaaag cacaggacat atatctaagc
    18781 tatggtatta caacagctca agaaggtcta atggaagaaa atcaatttaa tcttttaaaa
    18841 gcaatggcaa atcaaaataa attaaaaatt gatgttgtag gatatgtaaa tttgaaaaaa
    18901 agtaagcctg tagcagataa caatagagag tttataaaaa aatatataaa cagatttaaa
    18961 ataggaggct ataagatatt cttagatggt tctccacaag gtaagacagc atggttgagt
    19021 aaaccgtatg aaaattcaga tgatggttat tgtgggtacc ctatatacaa agatgaagaa
    19081 gtagaaaagt ttatagatat ttcactaaaa gaaaagatgc aactcttaac tcattgtaat
    19141 ggagatgcag cagcagagca gttgatagat gtatttgaga aagttttaac cttaaaagag
    19201 caaagtagta ataatatgag accagttatg atacatgctc aaacagtaag agaagaccaa
    19261 attgatgata tgaagagaat aaatatgata ccttcatact ttgtagctca cacatattat
    19321 tggggtgaca ttcatatcaa aaaccttgga gaagatagag catttaagat tagcccactt
    19381 aaaacaacta tagaaaaggg gttaatctac actcttcatc aggatacacc agtaatagca
    19441 cctaatatgc tggaaacagt atggtgtgct gtcaatagaa ttacaaaaaa aggtgtacaa
    19501 ataggagaaa atgaaaagat aagcccatta gatgccttaa agggtgttac tataaatgca
    19561 gcatatcaat attttgaaga agataaaaaa ggctcaatta aagaaggcaa attggctaat
    19621 ttgataatat tagatgaaaa ccctcttaca atcgacccta tgaaaataaa agatattaaa
    19681 gtattgcaga ctataagaga aggagaagta ttgtattctt tgaagtagat gcaagttaga
    19741 tattttataa tctataaaaa gtagttttat ataataagtt aggtagaatt aaataagatt
    19801 gcagttaaat caacaattat atttattatt aaattttaat tattgtattg aagatttacc
    19861 agtataattt tattgattct acctttttaa agaactatca atttattaaa gctatttaaa
    19921 atacattaaa caattaagta attattagtt gcagttatta gtataaaacg aatatgtata
    19981 ttactttgca gtagattttg gagctaagtt tataatagca aatttaaatt cattaaatag
    20041 attaccttac aacatttcat ataaaacata ttgtgaatct ggggaaatta ctacttttct
    20101 ttgagtattt cttataatca gttctaaaaa atttaatttc atacctatac ttaaatcatt
    20161 tattaaaata atactatcca aataagagat atataggtct atattataat ataaaaaaac
    20221 ttatatgaaa gttaataact atacaagatt gataaagaaa aagtcaaaat agataattga
    20281 ttagaaaaat cgatataatt ataatgaagt taaatctaga aatattctct tgaaattaaa
    20341 ttgtatttat ttaattaaat ataatttgac aatagataaa aaagtgagta aaatataaat
    20401 aaaaataata ggttcggata aaaaaaggtt tcttaacctc aagcataaaa catattatct
    20461 aagttatttg agattaagag aaaaaatcca atcttaggta ctgaggagga aaaaatgctt
    20521 gatataaaaa gaataagaga aaatttagat tgtataaaaa aagcaatgga aagaagggga
    20581 gaaaaagctt ttaaccttga tgaagtagtt aagttagatg atgaaagaag aaagattctt
    20641 caagaagttg aagttatgaa aaataaatta aatacagcat ctaaaaatat accaaatctt
    20701 ataaaagaag gtaaagatgt agaaaatgaa aagattaaac taaaagattt atctgataaa
    20761 attaaggtaa tagaccaaaa tcttaaagaa gtagaagaca agatggaata tctattaatg
    20821 agaataccaa acgtaccaca cccaggagta ccacaaggtg aaactgatga tgataatgtt
    20881 gaggtaagaa gttggggaga gactaccaaa tttgattttg aatctaaggc tcattgggaa
    20941 attggaacag aattaggtat acttgatttt gaaacagcta gtaaaataac cggttcaaga
    21001 ttcactcttt acaaaggctt gggtgctaga ttagagagag cattattaaa tttttacttg
    21061 gacacgaata caaaggtaaa tggatacaca gaagttattc caccatttat ggcaaataga
    21121 aatagttttt taggtacagg acagttacct aagtttgaag aagatatgtt taaaatagaa
    21181 ggactggact attttatgat tccaacatca gaagttcctt tgactaatat acatgctaat
    21241 gaaatactta aatttgaaca attaccaata aattatacag cttatactcc ttgttttagg
    21301 tcagaagctg gttctgctgg aagagataca agaggtttgg taagacaaca tcagtttaat
    21361 aaagtagaaa tggttaaaat agttgcacca gaagaatctt acaatgagtt ggaaaagctt
    21421 actaataatg cggagactat gctacaatta ttgaatctgc cttatagagt agtaaagata
    21481 tgtacaggtg atttaggatt tacggcttct tttaaatatg atgtagaagt ttggatgcca
    21541 agttacaata ggtatgttga gatttcatct tgttcaaact gcgaagattt ccaagctaga
    21601 agggcaggaa taagatttaa aagagataaa gattctaaag ctgaatatgc tcacacatta
    21661 aatggttctg ggctagctat tggaagaagt gttgcagcta tattagaaaa ttatcaacaa
    21721 gaagatggct ctgtgattgt tcctgaagtt ttaagaccat atatgggagt ttctgttatt
    21781 aaataagatt caaattatgt atttttaagc aacacttcta atatagaagt aataaaaaat
    21841 aattaacata gaagtgagac tataatctat aaaaaataat taatataaaa gtaatacaat
    21901 aatatagaag taattaaaaa ataataatta atataaaaat gtgtacaaac taatgaatat
    21961 tgatatagta agctatcata tgaaagagta tgtacacatt tttgtttact aattttttat
    22021 aatatgaaca taaataattt acaggaaagg aatattttat gaaaattcaa aatactgagt
    22081 ggggatatat tgaatggaaa catacttatg atgaaaataa tccaaaacaa gctatgaata
    22141 tatacattgc agtaactatg cctggtaaga aacattttaa tcatgtacat tatggtcaag
    22201 aacagatgat atatatttta gagggagagg gtttgtatat tataaatggg gtctggaagc
    22261 cattttatca agggatgatt ttttatatag aatctggtag cacacatgaa actataaata
    22321 caggagatag agaaataaaa gagttagtag tatcaaatat tgtaaacaat tttgaaacaa
    22381 gtgagattct tgaatttaat aaaaataata aaatagaaaa tactccagta aattatagtg
    22441 aaaatacctt aaatctatac gcagcagttg aatcaatacg aggtcagttt atagacccat
    22501 ttaaaatacc tttgattatt tatgatgatt actggaatat agttttaaaa aatccatatt
    22561 tccctttatt ttgttttgaa aaatgtaatc caatgaaatt cccacaaaat tgtgattgca
    22621 tgaatcaaaa aagtgctaat caatttacat gtaagtatgg tataaccata tataatattt
    22681 ctataatata taaaaataat agcatagggg ttataagagg tggatatatt ctaatgtctg
    22741 attcaagttt aggggttgga cataggaatt tatatgatat accagaaggt gcagctagaa
    22801 ctatgaaaag gttactcaat caaattgcta aaaatataat taatttttgt tcatttaatg
    22861 atataagaaa ggatttacaa gaaaaagaga agactatagc aagaacatat cattatggag
    22921 agcaacttga aatgaattta aaggtagctc aagatatggt tactaattta agaataaatc
    22981 atcacttttt atttaatacc ttaaattcaa tggtaagcat agcactagat gatggtagtt
    23041 atgatttgta tagtgcaata atagatttat caagaatgtt tagatataca atgaggtctg
    23101 atttaagatt tgtagaatta gaatctgaaa tattatacat tgaaaattat ttgaatttac
    23161 agaaattacg ttatggagat gcacttaaag taaaatatct tattccaaag aagttatata
    23221 acctttctgt gccttttaac tttattcaac ctattgtaga gaatgcattt acacatggat
    23281 ctagagatat tgacacagaa aagagaattg aaataattgc aagattagat tctcagtatg
    23341 ctattataga gattcataat aatggaacta ttttagataa aaataatata gacaaaataa
    23401 aggcaggtat tcgtattaat aatggtcatg gtttgtcttt aatatataca aaattcacat
    23461 ctgcttatgg aaataatttt gatatggata taaagtcgag tgataatgag ggaacttaca
    23521 taatgattaa aattcctagt gaaaattata aggagtatgt atagaacttg tgaaaaatta
    23581 ataagtttta taaatgttaa gaaatatatt agatgttttt atgttgtttt atatatctta
    23641 cttttttata ttcttaagct aaaagggagg tattctcatg agaagagcac taataataga
    23701 tgatgaagaa gctgttctaa aaataataac acattttata gaaatgaaag atatgccaat
    23761 aaaaattgtt ggtaaagcaa cctctggtga tgaagcagta gataaaatca ctggtttaga
    23821 gccagacata gtttttatag atattcaaat gccaatatat aatgggttag aagtaataga
    23881 aaaaacatct cacttatcta aaaaaataaa ctttgtagta ataactgctt ttgactattt
    23941 tgaatatgct caaaaagctt tgagattaaa tgtaaaagat atactcctta aaccattgga
    24001 catgaaagaa tttactaaat ctgtagaaaa aattattgga tatcaatata ccaataatga
    24061 tttattaaat gagatactgg aatatataaa tctaaattat agtaatgact taaagttaaa
    24121 tgattgtgct agattatttt taaccaatcc atctaatata tctaggattt ttaaaagtaa
    24181 tttgaataca acttttatat catatctaaa tcatataaga atagaaaaat ctattgagtt
    24241 acttgaaaat actacaaaaa gtataaatga gattgcagaa atagttggat ataatagcct
    24301 aaataacttt tataaaaact ttaagataaa aaaaggaatg actccaaaag tttataaact
    24361 gaatactaaa aattgaaatt gataaataaa aaatcaatat agataattgt ttgagtatgt
    24421 ctgaataagt atactttaat tataataaaa attaaagcgc tttaaacata tttaataata
    24481 ttaaacctta taaaagctgt acctatttat ataaaaaaat atatataaat aaaaagaaaa
    24541 agatatacaa aataaaaaag taaatcaaat actattctaa aaagacagaa ttttcattta
    24601 atttactgtg agtttatatt tcttagagga aggtaacttt ataatggagg taatttaata
    24661 tgtcagacaa agtgaatata aagaatatta tctgtattgc aggtgcttat ttagcgacag
    24721 caattggttc tgggtttgct actggtcaag aaattctaca attttttgcc tcacaagggt
    24781 atatgggtct agttggagca ttaatatcaa tggtgttgtt ttcatttctt ggtgctgaag
    24841 ttataactag aggtagagaa ttaaaactta aagaaccaac aagaatatac actttttatt
    24901 gtggtaagat tttaggaaaa ttttacgaat ggtttagtcc aatattttta tttgggattc
    24961 ttatagtaat gatttcaggt gcaggttcaa ctttaactga atattatggt ataaatcctt
    25021 acttaggaag agtgttgatg gctgttgcta ctttaattac agtgtctatg ggtttagaaa
    25081 aattagtaag tatacttggt cgtattggac cagtgatagc cgtatttaca attgctgttg
    25141 gattaataag cttgtttaaa cattttgatg gtttatctat ggttggagaa gctatgaaaa
    25201 acattgaagt tacaaaagca tcagaaagtc caatcatttc cggtgtaata tataatacat
    25261 taaatattat tgtaatgatt gtttttttaa caggaatggg agcttccatt gaaagtaaaa
    25321 aggatgcttt ttggggaggt ttattgggtg gaatcgtgtt tatgactgct ggtatagtta
    25381 tgtatttggc tatgatttca gatataggaa atttgtacat gaaagaaata ccatcacttt
    25441 atttagcaga taatatagct cctattgtag gtgtatgttt ttcagttgca ctaatattag
    25501 gcatctatac aacagctgtt ccacttttat ggtctgtaac caatagaatt gttgaagatg
    25561 aacaccctaa atttaaatta gtaacaacag taatagctat tttggcttgt ataggtggtt
    25621 ttttaccgtt tggtaaacta gtaaacattt tatatccata tacaggttat atgggacttt
    25681 taattttagt ctgtatggtg tataaagcaa ttacctgtag agaaaaatca acacaaggtc
    25741 aggagtagag ccacttatta gtaattttta gttaaagaaa ctttttatat aatcgaattt
    25801 aaaaagtcaa aatagttaaa aaaattgtaa aatatgataa tatatttaat taaaataaaa
    25861 tagtaaaata taaatataaa taaaa
//
LOCUS       DAMKOJ010000051        25824 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000051 DAMKOJ010000000
VERSION     DAMKOJ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25824
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.053"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(85..912)
                     /locus_tag="PC592_002332"
     CDS             complement(85..912)
                     /locus_tag="PC592_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4056295.1"
                     /translation="MKIKDNKTVFHVFVRIFLVAVLILTGTLLEEKINNVPVENISSK
                     GESTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYDKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENISPKNFWQENL"
     gene            complement(960..2396)
                     /locus_tag="PC592_002333"
     CDS             complement(960..2396)
                     /locus_tag="PC592_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF4056296.1"
                     /translation="MNTKNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDDLNNYFSGKFDKDTMVNLIRVTMGLDVTGDTDKNLKDSLHEAVNLDEVKRPIIS
                     IISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFIGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIDATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNRKENKYKK"
     gene            complement(2483..3352)
                     /locus_tag="PC592_002334"
     CDS             complement(2483..3352)
                     /locus_tag="PC592_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF4056297.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKIMRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(3510..4163)
                     /gene="phoU"
                     /locus_tag="PC592_002335"
     CDS             complement(3510..4163)
                     /gene="phoU"
                     /locus_tag="PC592_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF4056298.1"
                     /translation="MVNNSLDISIDTLKEQTVLMIEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEIDKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIDGKMVEIG"
     gene            complement(4191..4955)
                     /locus_tag="PC592_002336"
     CDS             complement(4191..4955)
                     /locus_tag="PC592_002336"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF4056299.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGSISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRIHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTIFTTPVDKRTEDYITGRFG"
     gene            complement(4974..5798)
                     /gene="pstA"
                     /locus_tag="PC592_002337"
     CDS             complement(4974..5798)
                     /gene="pstA"
                     /locus_tag="PC592_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF4056300.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGKMNFNFL
                     FSNYSASGDGGILPMIITTLYTVLVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSIGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(5800..6717)
                     /gene="pstC"
                     /locus_tag="PC592_002338"
     CDS             complement(5800..6717)
                     /gene="pstC"
                     /locus_tag="PC592_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF4056301.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKLAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGANWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPMIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(7664..8344)
                     /locus_tag="PC592_002339"
     CDS             complement(7664..8344)
                     /locus_tag="PC592_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056302.1"
                     /translation="MQTKILIIDGDKDNCQKLKKFMEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYITYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(8394..10409)
                     /locus_tag="PC592_002340"
     CDS             complement(8394..10409)
                     /locus_tag="PC592_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF4056303.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTHKSIRASNG
                     ILNIDNETFTKSKLVFLIDDWEFYNHKIFKPNDFIEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNDGKNRLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NLVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRVLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCIFFAIHVSYPFVHLLGLPLVNFTYAVEDSSY
                     FIAVLCIICINGSISKIEENKLYRFLILPLGITMSIMSIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAITSNRFEP
                     IFTGWQTEYCGFIIVILFSVMMINKNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLI
                     RAFENLIYNALTFTPFDGKIILSMDEEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNNPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(10481..11158)
                     /locus_tag="PC592_002341"
     CDS             complement(10481..11158)
                     /locus_tag="PC592_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056304.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(11738..11821)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(12054..12905)
                     /locus_tag="PC592_002342"
     CDS             complement(12054..12905)
                     /locus_tag="PC592_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4056305.1"
                     /translation="MFKKKIGVLLASTILVGALAVGCGSNSGGSGNSGNSGDSSKVSV
                     SGSTSIGPLMETIGEKFQEKNKGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEE
                     KSAGLKETKIAIDGIALITNTANPIKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVS
                     REEGSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKV
                     NSLKINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQAIVSEK
                     GFIKVNQ"
     gene            complement(13158..14942)
                     /gene="pepF"
                     /locus_tag="PC592_002343"
     CDS             complement(13158..14942)
                     /gene="pepF"
                     /locus_tag="PC592_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF4056306.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSNKEEIEKDISKVKNLIQEVKEYK
                     GKLSDSKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDDKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTVPENVYDMLAYADMQFPEIEDEDGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVYRQTMFAEFEKIVHERVENGEPLTADEFTDIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(15008..15673)
                     /locus_tag="PC592_002344"
     CDS             complement(15008..15673)
                     /locus_tag="PC592_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF4056307.1"
                     /translation="MIDIGSKEIALRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGVAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKSQLIIRNMEIECRNEEYWKVNFFVSYAKRIHLQDVMKEINMIEGVINVD
                     YLD"
     gene            complement(15824..15985)
                     /locus_tag="PC592_002345"
     CDS             complement(15824..15985)
                     /locus_tag="PC592_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF4056308.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(16063..16572)
                     /locus_tag="PC592_002346"
     CDS             complement(16063..16572)
                     /locus_tag="PC592_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF4056309.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKGL
                     SIIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            16779..16997
                     /locus_tag="PC592_002347"
     CDS             16779..16997
                     /locus_tag="PC592_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF4056310.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            17015..18961
                     /gene="feoB"
                     /locus_tag="PC592_002348"
     CDS             17015..18961
                     /gene="feoB"
                     /locus_tag="PC592_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF4056311.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLGEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIALNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFASFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIVEALIGGIIIALALFILFNKFKSTKNGSVCSGCS
                     ICSGCPSANSCSSKEDSNKKNSTH"
     gene            complement(19120..20175)
                     /locus_tag="PC592_002349"
     CDS             complement(19120..20175)
                     /locus_tag="PC592_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF4056312.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKKENLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGLISSEKYNDEINKILDAINRFEAVYKLSKQWIERNKKKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGIDPSI
                     PKDTKFHMKLGSKKLNK"
     gene            complement(20223..21023)
                     /locus_tag="PC592_002350"
     CDS             complement(20223..21023)
                     /locus_tag="PC592_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF4056313.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLSKEGNIFGPLLFLLLYNIPALALRIFGLKYGY
                     QVGVNSLDRIQREGLMDKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVAGIVLHAIGLL"
     gene            complement(21016..21807)
                     /locus_tag="PC592_002351"
     CDS             complement(21016..21807)
                     /locus_tag="PC592_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4056314.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMFDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGITGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQRAVFYAKQADFKRVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKIILDGLGVAGTLLPAVGFALLMDMLFSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLIEGEIDFE"
     gene            complement(21842..22264)
                     /locus_tag="PC592_002352"
     CDS             complement(21842..22264)
                     /locus_tag="PC592_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF4056315.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTKDKSADDA
                     EKEIRSILLNNKDSEAFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIIKSGLEEAKNGIVYVNELLENQNKIKNII"
     gene            complement(22280..22759)
                     /locus_tag="PC592_002353"
     CDS             complement(22280..22759)
                     /locus_tag="PC592_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4056316.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVIAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDNDDINNFKEISDLGIDIEFRMLPRDKKKQLSNLIK"
     gene            complement(22891..25647)
                     /locus_tag="PC592_002354"
     CDS             complement(22891..25647)
                     /locus_tag="PC592_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4056317.1"
                     /translation="MRDEILSFVNECALFNNFDELKKESGIVTEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKSKINDVVGPTKKSIYESLDELKNECKLLKQEIV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YIPNIEERGSIEKRKIVEHFIYEESKVLGLPIEITQITLNTILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIVFSPKQFSIEM
                     SNGTNKRSIIYQSFIKCLDYFDRLQKNEITKERFSKKSSNLVTRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLIMNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNAII
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKSKINSTMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVLAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSGVVENEKIKSIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLPNDKKIALYVHLSCM
                     IERLVRQAEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQISISEIGYIYNIIY
                     GLPQ"
BASE COUNT         8401 a         4514 c         2765 g        10144 t
ORIGIN      
        1 aagtatacct cttttttgta ttttttatat tatatgtttt actttataaa taatttactt
       61 tattttttac catatttaaa tttattataa gttttcttgc cagaaatttt taggtgatat
      121 attttctgta attggcaata ttgtatatcc tctctctttt aagattctta taatattatt
      181 taaagcattt aaactttgct ctttctcatg aattaatact actaattcat ctctttttct
      241 tccataatat aatatattac ttactatctg acttgtagaa gacttccaat cctgtgtatc
      301 caaattccag tcccaaatta aataatcatt tgccataagt ttatcatatg aaccttctgg
      361 catatatggt ttgcttccat atggtaatct tattaatttt gaactttgac cagttatttc
      421 ttgtagagta ttattgcatg tattaaattc cccaactgtt acttctgggc ttttatataa
      481 cttatgtata tcatgactta cactatgaaa acctattgaa ttttcctctt ccaaaactct
      541 tcttacttct tccttgtgat ttttcatatt ttgattaagc atgaaaaatg tcgctttgac
      601 atcattttct tttaaaatat caagcagtgc atttgtatat tttgatggac catcatctat
      661 tgttatgtat gctactttct cagaagtagc tcctggacct tttgtttctt cttgagatgc
      721 tttatatatg atttctccta aagtattact ttgagaaagt aattccagtg tactttcacc
      781 ttttgaactt atattttcaa ctggaacatt attaattttt tcctccaata atgttccagt
      841 taaaattaaa acagctacaa gaaatattct tacaaataca tgaaaaacag tcttattatc
      901 tttaattttc atcccccata tctccctttt ataaaagcat aagtttaaga cttaaaaagt
      961 tattttttat atttattctc tttcctatta ctttttatat ctctactaaa tattttttta
     1021 accttttctt cttctttttc tcctagagat tccactcttt tgattcccaa agaagttaaa
     1081 aattgtaata catttaaatt atcaaatgga gtttccatat tcgtactttc actatattca
     1141 tcaacattct tagtaccttc ttccacactt aaaatacgct taggacctcc tacacagcct
     1201 cctacacacc ccattccttc tataaatgta gcgtctattt ctttatttag aactttcttt
     1261 agaccgtcca tgcactcttt tgttccttca aatgcttttt cttcaaattt tatatttttg
     1321 tcaattcttc taactgataa cttaactgct ttacttacac ctcctgttct agcataaact
     1381 ctacctgaaa gggatgcctc tactctatta ctctcatcca ttattgctgg atttaactct
     1441 aatgcatcaa atatttcttg taactcttta aatgtaagca caaaatcaac tgcatctttt
     1501 atgtcttcta acattgcttc tttctttttt gccatacaag gacctatgaa tacaacttta
     1561 gcatctggat tcaaaatttt tacagctctc ccacaagcaa tcataggaga aacggatggt
     1621 gatacattct ccaatatctg aggaaagcta ttttgtatca aactaaccca aataggacag
     1681 caacaactag ttataaagca tccttcttcg tcctttttca tatgttcata ataatcatat
     1741 gcttcttttg cagtaagcat atctgctgcc aaagcaactt ctatcatatc ttcaaatcct
     1801 atcttcttta atgcagttct taatttacca gggcttacat ctttcccaaa ctgtcctata
     1861 aaagctggtg caactattgc atatacaggg ctctttatat cttttaacaa ttttatcatt
     1921 ggtataaatt ctattttatc tgaaattgca cccaacttac atcttgatac acaatcacca
     1981 caagcactac atacatcttc ctcattacaa ttaatatgct tacttcttat cttacatgac
     2041 tcatcttcct tattattttc atcacaatat ttgcaagcat ctgatattat ggatattatt
     2101 ggtcttttga cttcatctaa atttacagct tcatgtagtg aatcttttaa atttttatct
     2161 gtatctcctg tcacatccaa tcccatagtt actctaatta aatttaccat agtatcttta
     2221 tcgaattttc cactaaaata attatttaaa tcatctttta aatcttcatt taaaatttta
     2281 ttaggtaagt tttcaatatc ctctatatca tcattccaca ctgcttttac aagttcgcca
     2341 aaaagcttca ttttatatat ttctaatatt ttagaattat catttttagt attcataaaa
     2401 aatagtacct ccataaatta aacttatata tgtttaatat ttacaaagat actatttttt
     2461 atttattatt tatctactat tattaatatg atttatttaa ctttctcagc aattctattt
     2521 caatcattat tttcattaga tgatagttga atacaggact tttttcttca tctatattcc
     2581 agtctagctt atctacatta tatgttttct taaggtattt atatgtatgc tctttcaaat
     2641 aaagcttatt ttcaagtaac tctatagact gcatatgaaa atgtatttct ctacatatcc
     2701 ttaaggcgtt ctcaattttt tctatattag tttcactcaa actataatcc aactcatcaa
     2761 taagttttga atatatttct tctagttttt ctacttcttc ttcaaacttc tctacattta
     2821 aattttcttt tctcataatt ttatcttcaa taagcaacat cgaaagttct tctatctttt
     2881 taaattcatc tatgacgcta tttagataat ttggtctagc aacataataa ttaacaagaa
     2941 ccccaaacaa aacacccaca gatgtatcta acaccctatg taaagaataa tacacagggt
     3001 cactatttcc tacacctaaa tgtatagcca gaaaggttac acaggcaact actactgact
     3061 ttattttaaa cagattgcat aaatatattg agcacattac tcctagacca cataaaaaag
     3121 ggtctccagc tttaatgatg gcaaatatga atcctattat accacctaaa atagtacctt
     3181 ccactctatt gattcctgtc tttaaagaac cttttaccgt atcttgaaca gaaattatac
     3241 atgcaactaa agaataaaac atattctcta ctagatagtc accaagaatc atacataaag
     3301 tgacactaat tcctgttttt atagtcctca tacccatctt ttgaagtttc aaaattccac
     3361 ctcctaaaaa gcaccttata taaaatacgc atcctcatat ttaatatgtt cctagtatat
     3421 cacaattttt taaatttacc cattaatcat atttttttat caattctttc ttaatttaga
     3481 caaaaaaaaa ctgctttaaa gcagtttttt tatcctatct caaccatttt accatcaatt
     3541 gcaaaaatta tcttctcgca tacatttgtt atatggtctc caattctttc aaggtatctt
     3601 cctataagta gaagttttac cccttggtct atagtatttg aattttcatg cattattttt
     3661 aaacaatcaa tttgtacttg ttcatacaat ccatctacaa tatcatcttt agttccaaca
     3721 tcataagcta tacttgcatc aaataagatt aaagcttctc tagtctgaga catcatagac
     3781 ttacattctt ttgccatctt aggaatatct atcagctctt ttatataagc ctctccacct
     3841 atcttcaaca tttctctagc tatatttgct gcataatctc ctattctttc taactctatc
     3901 gatatattac ctaatgaata aataaatctt aagtcccttg ccattggttg ctttaatact
     3961 attaattcta tactcttatc tcttatttct tctcttaatt tatctatttc ttcatcatct
     4021 tctactactt ttcttgcacc ctctaaatcc ttctctatca tacaagtcac agacttttct
     4081 attgcttctt cacatttttc tatcataagt actgtttgtt cttttaaagt atcaatactt
     4141 atatctaaac tattattgac cattgtctaa ctcctttata gttatatatt ttaaccaaat
     4201 ctacctgtta tatagtcttc tgttctttta tctacaggag tggtaaatat agtttttgta
     4261 tcgctaaatt ctataacctc tccatttagg aaaaaagctg tttcatctga tatacgagca
     4321 gcttgttgca tattatgtgt aactatgact attgtgtagt ctttttttaa atcctctata
     4381 agttcttcta cttttaaggt tgaaattggg tctaaagcag atgtaggttc atccataaga
     4441 ataacttctg gtctcatagc aattgctctt gctatacata tacgttgttg ttgaccacca
     4501 gaaagtccta atgcagatga tttaagcctg tctttaacct catcccaaat agctgcacct
     4561 tttaagcttt cttctacaat cttatctaat tgcttcttat ctcttagccc atgtatacga
     4621 ggaccatatg ccacattatc atatatactc ataggaaatg gatttggctt ttgaaatacc
     4681 attcctactt tagtacgaag atttataaca tcatctgaag tatatatatc ctctccatca
     4741 acagaaatac ttcctttaat tgttacatct tcgattagat cattcattct atttaaagtt
     4801 cttataaaag ttgattttcc gcatccagat gggcctatta aagcagtaac cttattctct
     4861 tttatatcca tatttatttt ctttaatgct tgcttatcac cataaaataa atccaaatct
     4921 tttacactca tttttatctt atcgattaat tccattattc acacctctta aatttaataa
     4981 ttagccttat ttaatttctt agcaacgaat cttgccaaca tgtttagtgc taatacaatt
     5041 actattaaaa caattcctat actggctgct gttgctatat ctccactctc tttagtcagt
     5101 aagtatgagt gtacagttaa tgttcttgca ctatcaaata ttccacctgg catcttagct
     5161 acagtaccgg ctgtaagtaa tattgcagct gattctccaa ttatacgacc aattgataag
     5221 attactccag ataagattcc tggtattgca cttggaagta ctaccttata taaagtttga
     5281 aattttgtag ctcctaatgc taatgatgat tctctataag cttgaggaac tgtttttaaa
     5341 gcttcttctg ttgtacgaat tattactggt aatattatta ttgctactgt aagtgaacct
     5401 gcaactatgg aatatcccat ttttaatgta actacaaaga aaattcctcc aaataatcca
     5461 tatactatag atggtatccc tgataaactt tcagttgcaa atcttatagc tgtaactgct
     5521 tttccttttt tagcatattc ttgtaaatat atagcagcca atattcctat aggagttgct
     5581 acaactatag aaactaatac tgtatacaat gttgtaatta tcattggaag tataccacca
     5641 tcacctgatg ctgaataatt gctaaataag aaattaaaat tcatttttcc aattcccttt
     5701 ataaatataa atcccactat aactactaat gatactattg taaatagtgc tgatagatat
     5761 actaatgact tcaatagatt ctctttgaac tttctcatct taatttaccg ccttatttga
     5821 aagtttattt aaaactaaat ttaaaattaa tataaatgta aacaatacta ctccagttgc
     5881 aaatagcatt tcttgatgtg taccaaatgc gtaacccatt tcaagtgcta tattagttgt
     5941 aagtggtctt acactatctg ttattgcagt tggcataact ggtgaatttc ctgcaacaag
     6001 tattaccgcc attgtttctc ctaaagctct tcctactcct aacactactg cagctaatac
     6061 tccagatttt gcagcaggta atacaacttt gaatattgtt tctatttttg atgcaccaag
     6121 tgctaatgaa ccttctttat atgcttttgg tactgctctt attgctgttt ctgatacaga
     6181 tattattgtt ggtaacatca ttactgctaa tactattact attgctaaca aactttgacc
     6241 ttttggaaga ttaaatatac tttgtatcat tggaactatc actgcaagac caaatacacc
     6301 atacaatact gaaggtatac ctgctaaaag ttcaactgct ggtgacatta tttttgctaa
     6361 tcttttaggt gctacttctg ctataaatac agaggttaat ataccaacag gtactcctat
     6421 cacaagtgct ccaagtgtcg caaatattga agctactatc atagaagata ttccaaattt
     6481 attggcagaa ggaacccaat ttgcaccagt taaaaagtct ataaatgaat atccttcaaa
     6541 tataaatggt cttaatcctt tataaaatac gaatcctatt attaaaagta aacttgcaac
     6601 tgctactaaa gcactaagta gaaaaatatt ttttgctaac ttttcaatta cgtattttgt
     6661 cttattgcca ttattgtcat ttttttctaa acctactaat ctagacttta ctatcataat
     6721 atcctcccat taaaatatac ttatcgattt tcattctgta ttcaaaattt aaatttttac
     6781 aattcgtctt catcaaattt cctgtacttt tattctactt tttttaagtt aaatctatat
     6841 taggattaag ttaaacaagt gtaaaattat attcactttt ttaacattaa ttttactttt
     6901 aaaactatat ttgacattta ctttacatat aatggtgttt tgctatatta aaatagcaga
     6961 tataggtaat aatacgcttt atgtgtaatt tattacctat atctgctatt aagatttgtt
     7021 aactaaattt aacttttata ctacatatat aattgttatc tcctattgtc tatatcacta
     7081 ttattttcat aaaattgtta tgatacttga tgtttacaat aagtacgaat agacaaaaat
     7141 ataaaaatag gttttattag gcttatgata aaaaacaaca tttgaaatga tattttcaaa
     7201 cattgagcac caaaagttaa atcataaatt gccaaataaa tagaaataca tacaacaaac
     7261 attactataa atatagcaaa tagagctaat attttagtaa atgctaagat aagtgtatcc
     7321 atgtttagta caatgaagta tgctatatga tagtgtctga tattcacttc acaaaaaaag
     7381 gtagatgcaa agattgcaac acatacaatt aataatatga atatattaag gataaaaatg
     7441 aataatatat agatttatat atacaatttg tttatctttt caaatgtaac ccataaaata
     7501 atggtgcagg taaacatctt tttaagtaat aaaactgact gtaatttaac tgataaagtc
     7561 tagtaaatag gctttatcaa ttaaattaca gtcagctatt ttataataat ttagtttaga
     7621 tgtcgttaaa atttcacatt tataacaagt attaatatat ttattattcc ttattaaaat
     7681 aatatcctgc tcctcttatt gttataattt tttgaggatt tttataatct ttctctattt
     7741 tctttcttaa tccattcact gcaactacca cactatagtt atcctctaaa tactcattca
     7801 tccatacatg ttcatatatc tctttagtag tcaaagtctt ttcaggattc tctataaaaa
     7861 agtttaacaa cttattttct gttggagtca attttattat tttatcttct aactttatta
     7921 ctccactagt tctattatat tcctctaatt ttgtattatt ttcattatta tttacatatg
     7981 agttcattct tcttaaaata gcttttactt ttgcatataa tatttctaaa tttagaggct
     8041 ttattaagta atcatctcca ccagaattta aggcatttaa aatgctttgg tcttcattta
     8101 tgtaagtaat ataaacaatt ggacaagtag ttacatttct aattttttta caaagagtcc
     8161 acccatcacc atcagttagg attatttcta aaaatattaa atcatattta ttgctaaata
     8221 tttttccaat agcttcttca cagttatatg ctaaatctat acttattcct ttttcttcca
     8281 taaatttttt taatttctgg caattatcct tgtctccatc tattatcaat atcttagttt
     8341 gcattataat cactcctaaa tatcattatt cttttatatt aaataagcta ttattataaa
     8401 aaacatagac ttaattttat tgtaaaaaca gttccttttc ctagttccga atctacaaag
     8461 atttctccac catgctctct tataatggat ttgacaatat ataaccctaa cccttgccct
     8521 tttggattat tgttatctct ttctgtaaag aatctatcaa atacctttgg tatattttct
     8581 ggaggtatcc cttttccatt atcagaaatt ttaataattg caaatccatc ttcttcatcc
     8641 attgacaaaa ttatcttccc atcaaatgga gtaaaggtta aagcattata aattaaattc
     8701 tcaaacgctc ttataagcat ctctttattt atctttgcat atattttttt ctccaatatg
     8761 taagtttcaa agtttacacc acatgcttgt gtatctggca agttattttc atatatctct
     8821 ttaataaaat cattcagaca tattttttca ctaataccaa tacttttatc ttgtgatgta
     8881 aattcttgca aactacgtac tctattttgt acttcatttg acttttgatt tatagcataa
     8941 aggtaggttc ttgtctcttc atctacatga atattaccaa cctttatcaa gtctataaat
     9001 gcttgtatag ccgaaacagg tgcctttaaa tcatgtgcta catctgccaa aaatttttta
     9061 cgttcattta acaatgttgt aagttcatta gttctcactt caacttcatg ttcaagattt
     9121 cttgtaagtt tttcattctc ttttattatt attctattct tatttatcat cataacagaa
     9181 aataaaataa caattataaa cccacaatat tctgtttgcc accctgtaaa tataggttca
     9241 aacctgttgc tagtaattgc atcaaataat atgctaattc caaaaacagt atttactgaa
     9301 actaaaatat aagaacttat atgttcagag catgtctttt tatatattga aaccagtgaa
     9361 gacattaata tatatataaa tacaatatat ttatatatgt ctattaattt cccatatatg
     9421 ttgacaaagt acatatcata tggaagaaga ataattggta tcactataga catgatactc
     9481 attgtaattc ctaatggtaa aattaaaaat ctatacaatt tattttcttc tattttggat
     9541 atacttccat ttatacaaat aatacataaa actgctataa aatatgatga atcttcaact
     9601 gcatatgtaa agtttactaa aggtagtcct aacaaatgta caaagggata agatacatgt
     9661 atggcaaaga aaatacacat acacccaaaa tataagtaaa gtttactttt gtttgaaaga
     9721 aaccatacag acaacgaaaa tatagctatt gcaaaagttg tgaaacaaat tatactataa
     9781 aaaagtactc tataaaacat catattactt atatcctttg tttctcctaa tgcaggtgga
     9841 taatacaaac cgctataata atgtgaaaaa ttcgatacat tgattataat ttctgtgtct
     9901 ttctttgcaa taaaacttac tactaaattt ttaatttttg gtctatattt ttctgttcct
     9961 acatctccta atttagaaac catttctcca tttatccata cttcacttgc agaaaaaatc
    10021 tcaggaagct ccaaacttag taacctattc ttaccatcat tttttattct catacgataa
    10081 gtagcattcc catatggtga ttgattccct tttctcatag aaaaatctgg atattgacct
    10141 ataaaaacat attctggttt tatatcttgc tctataaaat cattcggctt aaatatttta
    10201 tgattataaa actcccagtc atctatcaaa aatacaagtt tacttttagt gaaagtctca
    10261 ttatctatat ttaaaattcc attacttgct ctaatagact tgtgcgtata tttgttatca
    10321 tatttataca gaagatttaa tcctgttatt gccaacagag agactatcaa tacaatgaga
    10381 gttcctttta gtatattata ctttttcatt gcatcaacca catctctttc atagtagtgt
    10441 taaataaaat aagaactatt tattaattac agcatctcac ctatggtaca aacttatatc
    10501 cttttcccca tacagtttga atatattgat gctccctgct taaagaatta attttttttc
    10561 tcatctgtgc aatatgaacc tgtactgtat gttgatcccc aatatcaggc attttccaca
    10621 cttggttata tatttctatc ttcgagaata cttgctcttt gttttcagct agaaacaaca
    10681 atatttcaaa ttccatagtt gttaaatcta tactttctcc atcaaaagtt acttttcttg
    10741 aatttacatt tattactaac gctgaaaact ttaacacatt aggaactgat gtaatatttt
    10801 tgtactgcct catacgagca tatattctaa gttcaagttc ttttaaacta taaggttttg
    10861 ttatataatc atctcctcca gctaaaaatc cccgaacttt ttcttcttca tgctcataat
    10921 tagataaaaa tattataggt atgttaacct tttcttttat atcattgcac attttatatc
    10981 catctatatc tggcaatgaa atatccaaaa ttatacaatc taaaactata ctctctacta
    11041 tatccatagc atctttagca gtctctgatg tatatacatt aaaacctata ttagaaaaat
    11101 aaatttgatt tatgtttaaa atatcaacat catcatcaac aaccagtaaa ttatacatta
    11161 caccactcca ttcaaaggta ttttaatcat agtctcaagt tttataatta ttacaaatta
    11221 taatgtttta ttttcatata taactagtat tattatttta taatatcttt acaaactaga
    11281 ctataatact taagtatttt tgaataattc ttgaatattg tattaaacat taagactcat
    11341 tattaaatac taattaaagt ctccgattgt tggagaatgg agattaaagt catttttact
    11401 tataaattta ttatttttct agaaacttgt atattggcta gtttgagtat tgatttatat
    11461 gatttatatg gttataatat aaaataaatt gtattatttt ggtaaatata ttgttacaaa
    11521 aggtttatat tctgcatctc aatgtttata aaaaagttat tttcttatta taatagcatt
    11581 atacttttta aaaaatttcc cttttccaac aaatggctac tttaaaagcc aaaatttcac
    11641 ctatcaataa aaatcttaac gacgaacact ctttttttca aatttttcaa catttttgtt
    11701 aattttaaaa caaaaaaaga ctatgcaata taaaaattat attcatagcc ggttgcacca
    11761 ctaactccat atatctctag atgcccaata ataagatata cttctcagtt tctaaaatat
    11821 ttttattaaa aatcttttat atattttcat aaatttcttt tttattctaa cattgtaata
    11881 ttattttgtc aatatttcca tatttttaga tataaaatac taaaatatat attttatcta
    11941 aagatatctt tatttttaca ttcaagaata gacaataccc tgcaagttaa agcatcattt
    12001 ttatgagctt atctcacagg gtattataca tctactttat attataattt atgttattga
    12061 ttaactttaa tgaatccttt ttctgaaaca attgcttgtc cttcatcact taatatataa
    12121 tctattaaag ctttaccttt ttctgataaa ccgtcttctt tattaactaa tataaatggt
    12181 cttgatattg gatatttatt agctattacg tttgcatcag ttgcttcaac atcatttatt
    12241 tttaagctat ttactttctc atcaacataa ccaaatgata tatatcctat cgcattttcg
    12301 tttccttcaa ctgtagtttt tatattccct gaaccatcac ttatttgtgc atctttagtt
    12361 aattcttctg agtcaaaacc tacaatttct tggaatccat ctctagttcc tgaaccttct
    12421 tctcttgata ctattactat tggtgcatca tttcctccta cttctttcca attagttatc
    12481 tttcctgtat atataccttt aacttggtcc attgttagat tttttattgg gttagcagta
    12541 ttagttatca atgctatacc atctattgct attttagttt cctttaatcc agcacttttt
    12601 tcttcatctt ttaaatctct tgaactcatt cctatttcag atgttccttc tatagcattt
    12661 tttatacctc cagaagaacc aatttgttgt acttctacac taacaccttt atttttttcc
    12721 tgaaactttt ctccgatagt ttccataaga ggacctattg aagttgaacc tgaaacagaa
    12781 actttacttg aatctcctga atttcctgaa tttcctgaac ctcctgagtt agaaccacac
    12841 cctactgcta aagctccaac taaaattgta ctagctaaaa gaactcctat tttcttttta
    12901 aacattttac ttacccccgc ttatatttta attttttgtt gtcatttttc tatatcttaa
    12961 taatacagat tttttgttaa atgaatatta gagcagggtt aagtaaatgt aaatattgtt
    13021 aaatacatgt aaaaacttaa ttttatataa tttattccta attagattaa ctttttaaag
    13081 ttagttttaa atagatataa acataataca actcatatta ttataattct tcattgaaac
    13141 tatcaaccta ttacattcta taactctttt tctagtttat taactaattc agcaaacaca
    13201 ttcaatgctt cctctataga ttcttttttc gtcatatcta caccagcaga ttttaattgt
    13261 tctagtggat attctgaccc tccacttttt aagaagttta tatatctatc tactgcagta
    13321 cttccttctg aaagtatctg ttgacttaaa gcacttgcag cagaaaatcc tgtggcatac
    13381 ttatatacat agaagtttga ataaaaatga gggattctag cccattctat tcctatttgt
    13441 ttatctacta ttgcagattt tccgtaatac ttttcgttta atttgtagta tatgtcagta
    13501 aattcatcag cagtaagtgg ttctccattc tctactcttt catgtacaat tttctcaaat
    13561 tcagcaaaca tagtttgtct ataaactgta gttctaaatt gttctaaata ataatttaat
    13621 aagtatatag tttcatcctt agatttagaa ttttctaata aataatttat aagaagtaat
    13681 tcatttaatg tagatgcaac ctctgcaaca aatatcttat agtctgaata taaaaacggt
    13741 tgacttgttc ttgaataatg actgtgaaca gagtgcccta attcatgaat taaagtgaat
    13801 agagaattaa ggtcattttt atagctcatt aatatataag gatgtgaatc ataacttccc
    13861 caagaataag ctcctccttt tttaccttca ttatcatata catcaatcca gccttcatca
    13921 aaagcacttt ttataacctt caagtattct tctcctaaag gcttaagtgc ttctaatatg
    13981 atatcttgtg ctttatcata tggtatatcc atgtcaaatt tatctgtcaa aggaacatac
    14041 aaatcataca tgtgtatttc attcaatcct aaaaatttct ttttaagctc aacatattta
    14101 tttagattag gaatactttt atctatagct gatataagat tattgtagac atctaaactt
    14161 acatcatctg aaaataaaga cgcttctatt gctgaattat actttctagt ttttgcgtaa
    14221 aatatctctg attttattcc accataaaga gttgaggcaa atgtattttt atatttctca
    14281 tatgttgaaa attcaccttc aaaagcgtct tttctaactc tactattctt actttttata
    14341 aataaagaat agtttgaatg agaaagcttg accttattac catcttcatc ttctatctca
    14401 ggaaattgca tatctgcata tgctaacata tcgtatacat tttctggaac tgtcgataat
    14461 tctgatgtag ctgcaagaat ttcttcttct cgttcactca aagtatgtgg tttatctctc
    14521 aatatatcct ttatatattt tgtataaaaa gataacttat catcttttaa atattcactt
    14581 aacttattct cttctatagc cagtatttct ggaactatat aagaagtagc cacacccaaa
    14641 tcagtagata acatttctgt cttagtagct cttccttgat tatcattaat tctagtatct
    14701 tcatgttgtt tcatatgagt atatacatat aaattttgaa caatcctaga tgcattttca
    14761 gagatattta atactttata taagttctcc ttactatcag aaagcttccc tttatattct
    14821 tttacttctt ggataagatt ttttactttg cttatgtctt tttcaatttc ctctttgtta
    14881 gagtacatct tatctatctt ccatttatac ttttcttcta ttgtacttct atcagttccc
    14941 atatcataca cctctatttt aatttgtttt atattttatt cactttacaa aatatattgt
    15001 atatatttta gtccaaataa tctacattta ttactccttc tatcatattt atttctttca
    15061 taacatcttg caagtgtatt ctcttagcat aagatacaaa aaaattgacc ttccagtatt
    15121 cttcattacg acattctatt tccatatttc ttatgataag ttgacttttt tcaaatttat
    15181 catataaaaa aggtatagag tccaaattgc ttaattttaa tatcaataca tttttttctt
    15241 gactaaataa aaatgtattg attatcctaa gcacaaataa tgctatcatt acaaataatc
    15301 cacctagaat tgccaattca taataaccat atccaactgc tacaccaata catgcagttg
    15361 cccacatacc agcagctgta gtgagacctt ttactccacc tttatttttt aaaattgctc
    15421 ctgcacctaa aaaaccaatt ccagataata cttgagcagg cattcttgct gggtcagcat
    15481 ttgtatacaa attataatca aagaataatt gaatcgaagt tattgaaaca atacaagaac
    15541 ctattgcaat tagtatatgt gttctaaatc ctgcaaactg tcttattttt tctctctcta
    15601 aaccgattat tcctccaatt attaatgcta atagtaacct taatgctatc tccttacttc
    15661 ctatatcaat cataatataa aaccctcctg acttaattac aacctatgtc ctacagataa
    15721 tttacacatc agaaatacta ttttatatct taatattatt attaatatat gtaaaatata
    15781 gccatctgtt aatttttgat acaaaaaaac ccacaactgt gggctatttg cttaggtaca
    15841 tgtatttatt tattaatata tctattttct tacttgattc tactaactct tcttgaaata
    15901 tttctggata ttctatgtat gtatttatct cttccctaac tgcttcaatc tcatttttta
    15961 acgcttctaa ttcattgttc gccataataa tcaccactat tacaaatttg tatattttta
    16021 tatacatttt atcaaacaat attatatttt gtcaatatta tgtcaataaa acttactata
    16081 aaaatgtttt aatttaggta ttgtatacct ggatactaaa cctacaaaca taccagttac
    16141 taatgatgcc attaacataa atggtaagta ccctatagca agtatatttt ctatgattaa
    16201 acttgcaact attaattgac ctatattatg ccctattgca cctataatgc ttatccctat
    16261 tattgataaa ccttttattt tgctcgctaa atacataaat aaaagactca gataagctcc
    16321 tcctatacta aatagtagat atgataaagg gcctgcaaat attgatgaca aaattaccct
    16381 gatagtaaca attataacag tatctttgac acctaacaac attaatgaaa ttaaagttat
    16441 aatattgctc aagcccaatt tcgcccctgg aaatataact ataagaggat ttggtatata
    16501 tgtctctagt acatataaag ctaaactata ccctatcata agacctaaaa atgtcatttt
    16561 tctagttttc attaagttaa ctcctccaaa ttttatctat catcttacat tataatacaa
    16621 aatatataaa aacacctaat ttagactaaa atatttttta atctatttag aataaatatt
    16681 agttatttca atgtgcaatt acctctataa ttcttgactt tttgtatcat acttgttaca
    16741 attttaatga taatgaattt cattaggagg tgttaataat gactgtttac gatttaaaaa
    16801 taggagaaaa aggatttatt aatagtatag atggagatat taaattatct aaaagattac
    16861 ttgcacttgg atgtataaat agtactgaaa tagaagttaa aaaggttgcc ccacttggag
    16921 acccaattat aattagattt agaggctttg accttgcgat tagaaaatct gatgctaaaa
    16981 atatttcttt acaataatag aggaggagct acccgtgatt aatgtagcat tattaggaaa
    17041 cccaaatgtc ggtaaaacta ctgtttttaa tctacttaca ggttcaaatc aatatgtagg
    17101 taactggcct ggtgttacta tagaaaaaaa agaaggattt cttggaaaag agataaaggt
    17161 tgtcgattta cctggtatat atgcaatgga tactttctca aatgaagaaa aggtttctaa
    17221 atcatattta gaaaatgaag atgttgatgt aatagtaaat gtagttgatg cttctaattt
    17281 atcaagaaac ctttatttaa caactcaact tatgcaattt aacaagccta tagttatatt
    17341 gcttaatatg ttagacattg cagaatctaa aggagttaat atagatgcta aaaaattagg
    17401 cgaagaactt ggagtaattg ttgttccaat tatagcaaaa aagaaaaatg gcgttgatag
    17461 gatagaagaa gagattaagg gagctacaca aaaagctttt atatatcaaa aaaactttgg
    17521 aagtgaaaca gaaacatata aaaaattaga atccatttta tcaagatgta caaaaactac
    17581 atatacacag aaaaaatcta tcagtgataa gatagacaat atagccttga atcctatatt
    17641 agcatatccg atatttattg gtgtattatt cctcttattt aaatttacct ttgattgggt
    17701 tggaggaccg ctacaagagg gatttgctag tcttatagag gcttatattt ctgcacctgt
    17761 tagtgatatg ttatctaact ctagcccatg gtttaaatca cttatagttg atggaataat
    17821 tggaggtgtt ggtggtactt taccattctt ccctttaata tttacattat tctttggtat
    17881 atcgttgttt gaagatagtg gatacatgtc aagaacagca tttttaatgg ataaagtcat
    17941 gagaaaagtt ggtctatctg gtaaagcttt tatacctata gttatgggta tgggatgttc
    18001 ttctccagct ataatggcaa ctagaacatt ggaaagtgaa aaagatagaa gagttacagc
    18061 tcttattgca ccacttatga cttgtggagc aaagctacct atatatgcac tatttgtagc
    18121 tatattcttt ccacataatg ctgctttagt aactacgtca ctgtacttag taggtatagt
    18181 tatggcaatt gtagttgcat tattcttaaa taaaacagcc ttcaaaacag aggctgaacc
    18241 atttatatta gaattaccag aatatagaat ccctactata gatgcactta ttaaaaatac
    18301 ttggaataaa tcaaaaggtt tcttgataag agttgttact gtcatgtttg caatgtcagt
    18361 cgtaatttgg ggactttctt cattcaatgt ttttggatat acagaggata taaatgtaag
    18421 cttcttggct actctaggtc atattatatc tcctatattc aaacctcttg gttttgatga
    18481 ttggagaact tcagttgcta ttttaagtgg tcttggagca aaagaaatcg tcgtaaactc
    18541 tttaaatata ctatatggta atctaactgt tgtcttacca acaatattta atggagttac
    18601 tgcatatact ttcttgatat ttactgcttt atatactcca tgtatagctg cacttgcaac
    18661 tatgaaaaaa gaatatggca ataaaatgat gtttgcatca tttgcatatc aatttatact
    18721 agcatggata atggctttta tagttaaaag tataggtgga gtactattta tgggcaattc
    18781 aatagtggaa gctttgatag gtggaataat tatagccctt gcacttttta ttttgtttaa
    18841 taagttcaag tctacaaaaa acggaagtgt gtgtagtgga tgttctattt gctctggatg
    18901 tccaagtgct aattcttgct caagtaagga agacagtaat aaaaaaaata gtacacacta
    18961 atatataaat attttagttt aaaataacgt agaagtgagt gtcttaaaat taacttttta
    19021 gttcattagg cactcttttt tatatggaat aaaatatatt tttatcattt caacagtcaa
    19081 aaagaggctt atctatattt tgagacagcc tcttattttt tacttattca atttcttgct
    19141 acctaacttc atatggaact tagtatcttt tgggatgctt gggtctattc cccttaatgt
    19201 aggtatttcc ccacatatta gttgtatagg tactataaaa ttaaatgttt gatagtaagg
    19261 attatctgta atatctattt ttaaattttt atcattttct gtaacatctc tacctatagc
    19321 aaatacattt tccgtccaac cagaaagtac atcaatcatc ttagttactc taggttcttt
    19381 tcctgtatct agtataaata tagtagaatc actatttata gcattatata taccatgtat
    19441 aaattcttca aattcatacc cagttacagg tattctcatt gtttccaata atttcaatgc
    19501 tgcttctaat gtatctccat atatatcaga gtggcctatt attcttattt ctttagaatt
    19561 aactaacttt tttttgtttc tttcaatcca ttgtttagac aacttataca ctgcttcaaa
    19621 tctattaatt gcatctaata tcttatttat ttcatcattg tacttttcac tagatattag
    19681 tcctttttct ctagctattt gaagacctaa caacattaag tttaactttg tacaataata
    19741 tccttttgtt ttagctccag atttttcttc tccacaattt actgttaata tataatcaga
    19801 aatctcatct attagagcat ttttacaacc cgccatagat gctattttac accccttgtc
    19861 ttcagccaac ttcatagcat tgtatgtaga ataactactc ccaccttgag atacacctac
    19921 tactagggta ttttcattat caaacttgaa tgtatcttca gttatcataa atggatacat
    19981 tttcacaaca tctatatcta ataagttttg taaatatggt tgcacttgca ctcctgagtg
    20041 atagctagta cctgaaccag ttattataat cttttttaga ttttctttct taacttcatt
    20101 gaataagcta tctgcattag atataatttc tctcattcta actggtgttt ctaacatata
    20161 atcttgtatt gtcattttat acgccttcct tatctatata ttcaataaat tacaattaac
    20221 ttctataaca aacctatagc atgtaaaact attcctgcta ctatagttcc tatagttaat
    20281 tttgttacac ttacctttct ctttaacatg taatatatta caaatgcaaa ggttaaaggt
    20341 aacatattag gtattatttt atctagtata tcttgtaaaa ttacttctgc accatttaag
    20401 ttaaatttca gaggagtagt tatactcaac atagttgcaa ccattcctcc tacaacaaat
    20461 aaaccgacag ttgtagccat agacattatt ttatccataa gtccttctct ttgtattcta
    20521 tcaagagaat ttactcctac ttgataacca tacttaagtc caaatattct aagagcaagt
    20581 gctggtatat tatataatag taagaataat agtggtccaa agatattacc ttcttttgaa
    20641 agtgatactc ctactcctgc tgctataatc ctaaatgttc cccagaatag tgaatcacca
    20701 attcctgcaa gaggtcccat aagagctgtt ttaacagcac taattgaact ttcatcaaat
    20761 tctggattat tagcattctc ttcttccata gctgctgtta tacctaatat agcaggaact
    20821 accactgtcg ttgtattaaa aatctccaag tgtctttcta ttgcttttgc ttgattttct
    20881 ttcttattgt ataacttctt tattgcaggt aacattgaat aacagtaacc taagttttgc
    20941 attctttcgt aattaaatgc accctgaaga gcaaatgaac gccaaaacat acttcttaat
    21001 tctttttttg ttaatttatt caaagtcaat ctctccttct atcaaagtat taattgctaa
    21061 ttgaggattt tgattatttt ctttgttatt gatataaaaa tttagtacaa atgctacaca
    21121 tactccaaat aaagctatag cagttatatc caatccacca taagatgcta ataaaaaccc
    21181 tataaagaaa aacacagaca ttttttttga aaataacata tccataagca atgcaaaacc
    21241 tactgctggt aacaatgttc ctgcaacacc caaaccgtct aatataattt taggtattgc
    21301 atttatcaat gctgtaactt tatcagcacc aatcataatt gctaaaaaag ttggaactga
    21361 tgtacttaaa aagaataata ttactggcaa ccacatcatt atggtaactc tcttaaaatc
    21421 agcctgttta gcatagaaaa ctgccctttg agaaaaatac gaatttatta ttctaaccag
    21481 tactccaaga gattgtgcta agactgctac tggcactgct actgctaaag caacttctgc
    21541 accattacct gataatatag caaaagctgt acctaataca cctcctgtta ctacgtctgg
    21601 aggagtagct gcacctattc ctgtaattcc catccaaatt aattcaagct gtgcaccaat
    21661 cataattcct gattttatat ctcctaaaac taatcctact aacatacctg taactatcgg
    21721 cctatcaaac atagattgac caaatatacg cccatctaat ataccaactc ctgctataat
    21781 agctaacata gtagcttgta ctaacatagt taacctccat tttaacttag tttaatttac
    21841 attaaattat atttttgatt ttgttttgat tttctaataa ctcatttaca taaacaattc
    21901 cattttttgc ttcctctaag cctgatttaa ttattagttt tgtatcctct tcaactaata
    21961 aaagtataga taaaagcatt ggtaaattta ctcctgtcaa taattcaaat ttgaaccctt
    22021 gtaaaagtaa gtttgtacat atgtttgcca cacttccacc aaacacatct gttaatacaa
    22081 caaacgcttc actatcttta ttatttaata atatacttct aatttctttt tcagcatcat
    22141 ctgctgattt atcctttgtc atacaaaaat actcaatatt agttaatgaa ccaattatca
    22201 atttacttgt atcaacaagt tctctagaca attctccatg tgtcgcaatt agaaattttt
    22261 tcattctctt tctcctaaat tattttatta aatttgatag ttgtttcttt ttatctctag
    22321 gtaacattct aaattctata tcaattccta aatcacttat ttctttaaag ttatttatat
    22381 catcattatc aacagcaact aaatctgtaa gtttcttctt tccttcttca tatcttaacc
    22441 ctcctacatt tatttctttt aatactcctc ctgagttttt agctataact aaagcatctt
    22501 tggtattttt tactaacact aatacattgc ttttctttga agaagcaaat ttttctacta
    22561 tttctccaga ctcctctacc ccccttatat ataaagttac attgctaggt ttagctaaat
    22621 tcagtgacat agctttcatt tggtcatttt ttgcttcatc atttgcaact agtattacat
    22681 ttatccctag tgatgttgcc catccatatg ccacctgacc atgtatcaat ctgtcatcaa
    22741 ttctcattaa agataccatt ttcctcaaat cctccatcat acattaaaat ttttattgtt
    22801 tgtcctctaa tttatctata aaagcaaaaa gtatgccaaa tactggcata ctttttcgaa
    22861 tttcattcac ttattttgta atcttgtatt ttactgtggt agaccataga tgatattata
    22921 aatgtatcct atctctgaaa ttgatatttg cacactataa ctcttttcta gcacactaaa
    22981 tgcatttttt attaatttta cttcactatg atggtttttg attaacaaat ccatatcagt
    23041 atactcttca atttcagctt gtctaactaa tctttcaatc atgcaactta agtgaacata
    23101 taaagcaatt tttttatcat ttggaagttt tttcttttga atattttcta tagcgttgat
    23161 tccctcttct attctctcta ttatcttctt tgaatctaaa atagttagac tgtctattac
    23221 tctaattaat gaaaaattct ttacaataga atcatttatg ctctttattt tttcattttc
    23281 tactactcca ctaaatattc taaaaacatc atcttctcct tttcctgata ttatatcctc
    23341 taataatata aaatccaccc cattcacatt tggattggca gttcctacta tagccagtac
    23401 atcatacatt tcaaaaactg gttctttatc tcccatagaa acaagactat cataatcata
    23461 aggtattatt ttgacatcaa ctattccaat taaactttct gaaagtaggt gttggatttt
    23521 tatagcagta cctatccctg taaagcaaga tgatattata gcatattctt tatttttttg
    23581 aggataatac aattgtatat taggtttagt ctcttcatcc ataatttctg caatctcttc
    23641 aatgttctta ccttgcatta ataaatttcc tacttctagt gcagaaatgg tggatatttg
    23701 gtctataaat aacattgtgc tatttatctt actctttaaa tcttcgtata taagattaag
    23761 agagcccata tcaaataaca caattaaacc attctttatc ctatctccct ctaggtatct
    23821 agacatttgt tttgatacat cagcaatggt agcatctata ggcatatcaa tagcagtgaa
    23881 tatattttta cccaacattc gattacatac attcgccata ctactggcag tagcataacc
    23941 atgtgctata ataatcgcat taacctgatt aaatttcatt cttataattg tcgacttaat
    24001 aaatataatc attatgattg tatctacatt attaagatac atatccaatc tattcattat
    24061 taatgttgat attttactta ttatagagta ttctttgtaa ctctcttttt ttaaatatat
    24121 tagcaattta ttttctaaag ctttatattc atcagacaat tgatacgatt catctttcaa
    24181 ataaagataa gacgaaaatg ccaatacatt attcccatca tattttatat tgttattaac
    24241 ttctaaattt ctaaatatat cctgcattat tgatattata agctccataa gtacgttatt
    24301 attttcatca ttatttgaaa aaactaaatt atccattaat ctagtcacta gattagaact
    24361 ctttttacta aatctttctt ttgttatttc atttttttgt agtctatcaa agtaatctaa
    24421 acattttata aaactttgat atattatgct tcttttattt gttccatttg acatttcaat
    24481 actaaattgt ttaggtgaaa agacaatgct tttgctttta ccactttgaa attgaaatat
    24541 gtctacattt tctatataaa gatttctagg aaggtcttga agagtaacga aaatatttcc
    24601 atttcttctt tgattttttg cataagctcg tccacatgca tattttatta catttttaca
    24661 ttcgcctata ttccccttga attttatctt taaaatcgta tttaatgtaa tttgagttat
    24721 ctctataggc aaaccaagta ccttactttc ctcataaata aaatgttcta caatctttct
    24781 tttttcaata ctccctcttt cttctatatt aggaatataa atatttatgg gtattcttct
    24841 taaaaaagtt tgtaaaaact cagataggct ctctgttgta gcaaatatta atcttaccct
    24901 agcttttcta attactccat tctctccaat tctggaaaac gtacctgtat ccataaatgt
    24961 aaataacttt tcctgacctt cactatttaa tctatgtact tcatctaaaa ataaaacacc
    25021 gccatcagac tgttctatta gacctgctct agattcattt gccccagtat atgctccttt
    25081 tacatgccca aataatagac tagacaataa ctccaaatta ttataatact gcgcacagtt
    25141 taacacattg tatggagaat ttttttctaa tacattacta cttacactat atttatatat
    25201 tatcttggct aaaaaagttt ttcctactcc actttcacct gtcagcatta tcgtaagccc
    25261 accatttgga taaagcacag cagtttttat ttgttcgatt acctctttta agctattatc
    25321 gtatcctatg atactattaa acacaatctc ttgctttaat aatttgcact catttttaag
    25381 ttcatctaaa ctttcataaa tacttttttt tgtaggtcct actacatcat ttatcttact
    25441 tttaggtaaa aaaataacag gtctactatt tatctttata agattatcag attttactaa
    25501 gtcatttaat aatctacttg attgagttct acttaaatta aactttttta ctatgtcttc
    25561 tgtcactatg ccactttctt ttttaagttc atcaaagttg ttaaataatg cacattcatt
    25621 tacaaaactt aaaatttcat ccctcatgtt caacctccaa tacaaatatc aataataata
    25681 taatattagt atatcattta tatatttatg aaaaagataa ttatattcct atcttaattc
    25741 tcttttgtaa gattgtaaaa tcaaactttt tataagtata aaatctagat tttttaacat
    25801 aatctcaaga ttcttatctt ccta
//
LOCUS       DAMKOJ010000052        25785 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000052 DAMKOJ010000000
VERSION     DAMKOJ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.054"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            387..1253
                     /locus_tag="PC592_002355"
     CDS             387..1253
                     /locus_tag="PC592_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF4056318.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISKIIPIHDILLQSVYGGILSGLGVGIVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSDEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            1495..2304
                     /locus_tag="PC592_002356"
     CDS             1495..2304
                     /locus_tag="PC592_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056319.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVSKEIRSIKSMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYIGKFLEGKMEGKGSYTFFVDEGT
                     AMEYIGEFKEDKKNGKGNFVFSNGNEYIGYFEEDMMNGIGNMLYNSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEILYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            2445..3509
                     /locus_tag="PC592_002357"
     CDS             2445..3509
                     /locus_tag="PC592_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF4056320.1"
                     /translation="MKKLIALVLVILIVLFYSPELLKEGNDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKNQNVQSNNTEGDNLGESDIKNFEKISLEDNLSYVLSSIGKPGRI
                     DTSEYGFDWYVYNQYGKEFAMVGVENDEVVALYSNSINSSENQGIKINQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEKNRVCSYLIIDKSTEDEFK
                     KLYPDDREELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            3537..4256
                     /locus_tag="PC592_002358"
     CDS             3537..4256
                     /locus_tag="PC592_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4056321.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIILISNFSKVSALMTDTSGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            4279..4863
                     /locus_tag="PC592_002359"
     CDS             4279..4863
                     /locus_tag="PC592_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDF4056322.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKIRDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEYFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSISHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEVTATTDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFIIEARERVHM"
     gene            4865..6214
                     /gene="pabB"
                     /locus_tag="PC592_002360"
     CDS             4865..6214
                     /gene="pabB"
                     /locus_tag="PC592_002360"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDF4056323.1"
                     /translation="MIREINTTLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVINDTNLPFVGGAVGYLSYDLGNYIETLPRT
                     AIDDIKMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIKLEEKIMDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDTHILSNSPERFIRCVNNRIETRPIKGTRPRGKNKE
                     EDLKLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDGKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            6204..6947
                     /locus_tag="PC592_002361"
     CDS             6204..6947
                     /locus_tag="PC592_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV family protein"
                     /protein_id="HDF4056324.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIKVKNGLPIDLNIHVERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVIDKALRITVFDEGYNISIRDIPYNQEMYEKGF
                     RLTISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIEELLE"
     gene            6981..7682
                     /locus_tag="PC592_002362"
     CDS             6981..7682
                     /locus_tag="PC592_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056325.1"
                     /translation="MIGCIYEVYNEEISKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDINYFSKDGIKKLLSNREYFFVKEMKDAKVLF
                     DRENISHTIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            7708..8280
                     /gene="folE"
                     /locus_tag="PC592_002363"
     CDS             7708..8280
                     /gene="folE"
                     /locus_tag="PC592_002363"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDF4056326.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLNEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            8346..9137
                     /gene="folP"
                     /locus_tag="PC592_002364"
     CDS             8346..9137
                     /gene="folP"
                     /locus_tag="PC592_002364"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF4056327.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKISIEMA
                     ISCGVKKEKIVLDPGIGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            9148..9513
                     /gene="folB"
                     /locus_tag="PC592_002365"
     CDS             9148..9513
                     /gene="folB"
                     /locus_tag="PC592_002365"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDF4056328.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYDVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            9506..10012
                     /gene="folK"
                     /locus_tag="PC592_002366"
     CDS             9506..10012
                     /gene="folK"
                     /locus_tag="PC592_002366"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDF4056329.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERKLHRERIVHWGPRTIDVDILFFN
                     DVVSTDERLIIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEERDEVKEL
                     VGYERKPI"
     gene            9993..10778
                     /gene="aroF"
                     /locus_tag="PC592_002367"
     CDS             9993..10778
                     /gene="aroF"
                     /locus_tag="PC592_002367"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF4056330.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            11033..12823
                     /locus_tag="PC592_002368"
     CDS             11033..12823
                     /locus_tag="PC592_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF4056331.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMSIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDIINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGLLIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            12841..14007
                     /gene="rpoD"
                     /locus_tag="PC592_002369"
     CDS             12841..14007
                     /gene="rpoD"
                     /locus_tag="PC592_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDF4056332.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHEDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            14169..14858
                     /locus_tag="PC592_002370"
     CDS             14169..14858
                     /locus_tag="PC592_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF4056333.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGRVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFKDFIEKKIKTYSSIVSKLEGKNGEAIDKKRNESE
                     VTIKKLENLIK"
     gene            14872..15969
                     /locus_tag="PC592_002371"
     CDS             14872..15969
                     /locus_tag="PC592_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF4056334.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSADLKGRLIQKLIKNNVSLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDVTKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSKKIKEKLNMKHIRVVGNLS
                     TNITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEISEIEVIKSSVYLNPFSTI"
     gene            16031..16603
                     /locus_tag="PC592_002372"
     CDS             16031..16603
                     /locus_tag="PC592_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF4056335.1"
                     /translation="MKAAVIFHSVCGSTYLLAREYKEALKEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGRELLDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSIRGGHPAYG
                     ILHIAGDNSNIRPSDDVKIGIRDYLERLSI"
     gene            complement(16663..17130)
                     /locus_tag="PC592_002373"
     CDS             complement(16663..17130)
                     /locus_tag="PC592_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF4056336.1"
                     /translation="MFKEMRLKKREMTKEDTIEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFDDSIYFHSARNGHKLDNILKNNKVSFLVVANENVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDVNLTTVVKIEIDHISGKASRL"
     gene            complement(17516..17992)
                     /locus_tag="PC592_002374"
     CDS             complement(17516..17992)
                     /locus_tag="PC592_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF4056337.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLNVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(18109..19200)
                     /locus_tag="PC592_002375"
     CDS             complement(18109..19200)
                     /locus_tag="PC592_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDF4056338.1"
                     /translation="MSKIECLFTIFPILILMYATFYFMPYFVGKKHIYGVSIDQEYKN
                     YNHFIKLDKKFKNLLSLGFIIDLILVFILVFTFNKLELSYFISIIVFLLYESILYIHT
                     HKKAKNLKSELYSKLGHIDVDSKLIIDMDFINKKNKIIKKFKIIYLIPILFTFGMSIF
                     IVFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTNFCLMVLLYITSIGSIKSR
                     IKIDTNRIKESRIENIEYLNKIGYLFLILMTIMTIQFFTTILSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKSNSSYSPEENEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFLLFSLIKSLLL"
     gene            complement(19193..19582)
                     /locus_tag="PC592_002376"
     CDS             complement(19193..19582)
                     /locus_tag="PC592_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4056339.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDNYEVKYYE"
     gene            19774..20220
                     /locus_tag="PC592_002377"
     CDS             19774..20220
                     /locus_tag="PC592_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056340.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMLTGAVLTGVGAYAVYKMIKNRK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKDDVDLHEDAKKDNIYKEDEYKKYEEE"
     gene            20487..21191
                     /locus_tag="PC592_002378"
     CDS             20487..21191
                     /locus_tag="PC592_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056341.1"
                     /translation="MVKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSGKEMISSN
                     EYSLILLDVTLPDGTGYELCQYIRGFSQIPIIFLTACDEEVNIVMGLDIGGDDYITKP
                     FRIRELISRIKAVLRRKANTVEESKKILKFGDLSIYTLEARVYKNDKEVFLTSVEYKL
                     LLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCEPIYIETV
                     RGLGYKWIGSENSVSI"
     gene            21169..22422
                     /locus_tag="PC592_002379"
     CDS             21169..22422
                     /locus_tag="PC592_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4056342.1"
                     /translation="MKIVFLYNPEVKKFLSKYVTLIFVIIIISIGFSVINVSLTKDMI
                     VRNNQAIIGTLSSKYPNLESEIVDIITQGKSMENTDYGKKILSKYNYDKSIRINSEPI
                     ISKLVLDTIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKSFDMKN
                     KNQEGQIGLLKTELLKMTTILNEKVELLKTEKIFLNNTISDISHQLKTPMTSLIMLND
                     LLYNDIPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHR
                     AMQSMKIPMEIKNQKLTIEGSDNISYIGDIDWSVEALVNIIKNCVEHTPEFGNITITY
                     KENPLFSELIIKDDGEGIHKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNG
                     DIYVNSEKGKGTEFHIIFHKMYDSD"
     gene            22502..23179
                     /locus_tag="PC592_002380"
     CDS             22502..23179
                     /locus_tag="PC592_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056343.1"
                     /translation="MEVLRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLNDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            23180..25741
                     /locus_tag="PC592_002381"
     CDS             23180..25741
                     /locus_tag="PC592_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056344.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQVRETIKNDGSFHVTFYDVNRKNVEYVTKSAEVEKYAFTKQLGYSKLENSENGIVS
                     IKQYDKNAINGYKISIKEGRFPAKEGEIVLSENIINLIDDNLKIGDKITLKVGDMFDS
                     SKKKIDSMVFHEGDYIASEKDRTFEVVGIIKKPGFERYNGIATAITYFNPMDNYNDTI
                     NVSVEVRNPKEVYEVSNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYADINSSI
                     KSIIIAVTILVIICTIATVYNSFSISITERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTQMSLRIVYNPIIIIVSIIIVLFTIF
                     ISILLPAISASNISPLNVIKNTGEYKVRKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IVTLFSLMISVIIFISFSGFTLLLLRSEEIRNSQRKYDLYLTAKGTARSIDDTVSELE
                     GIDGIKNFELATGQYVSIRVSENKINKSKEDLIGKYYQKYKVGDSYEYDFSNNDLIFP
                     GDFAIRNKINNLIQGSFNKERAIQENGVILVRKSSFESKGKKGVVELTNYKVGDTVTC
                     EYLDENASSKKIKVKILAITDEERLGMGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESAITESEKQNLKVIKIFVYGFIAVISLVSVTNI
                     LNTVSTSINLRKGELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGMTLIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPISKLNKENIIDNIRRESI"
BASE COUNT        10540 a         2566 c         4565 g         8114 t
ORIGIN      
        1 tttcatttag gaattaattg taaagatata attattaaat tcaaatttgc taaaataaaa
       61 taaattactg ctaaaatgga tatttagaaa aaaatactat aaatttacta tattgcaagt
      121 taaataataa gtagtatcat actatgctag aaaaagtttc atttaaagca taaatgagat
      181 gatttgaacg tttttaaaga ttggaatata aaagattaca ctagacatat atgaaaaaga
      241 taatataata gatgatgtaa tagatgacag ttcaagaaat tatataaaaa atttatttga
      301 aatattatct attacatcag gaataatata tgtaagagta agcttttaaa attctaagga
      361 tttagaaaga ttgaagggag aaagaaatga gtgaagttaa gaatacccta caaaaacatc
      421 cagttttaag atattcaaca atgctatttg ggatgttgat gacatctata ggaataaatg
      481 ggttcttaag accagcacat ctacttagtg gaggtgctac aggtatagca acatctataa
      541 actatttgac caatataaat gtaggtttat taacattttt aatcaatatt ccaatattta
      601 tcttagggtt tatataccta gaaaaagagt tttgtatttc aagtttggta aatatgattg
      661 tattttcatt attattaggt gcaactcagg aaataagtaa gattatacct atacatgata
      721 tattgcttca aagtgtatat ggaggtatat tatctggttt aggggttgga attgtattta
      781 gaactaggtc ttctcaaggt ggtacagata taatagctgc aatactaaaa attaagaaga
      841 atatagaaat gaaagacact gccttagcaa taaatggctt gatagtactt acaggaagtt
      901 ttttatttgg gttagattta gcattataca ctcttatagg tctatttcta aatgcgtatt
      961 caatgagttt tattaaagat gcaatgaatt accaaaaatc tgttatggta atgtcagatg
     1021 aagtcgattt aatagcagaa gatataatga agagtttagt tagaggtgta acttttttag
     1081 atgcagaagg tgcatatact catcaaaaaa agaagattat atatacaata gtttcatcaa
     1141 atgagatacc aaagataaaa gacatagctt tgaagtatga taaaaaggct tttatatctg
     1201 taaatgatgt tacagaagta aaaggaagag ggtttaaagc aaaagactta tagaaaattt
     1261 taaaagctgg gagtttgtaa tgtaaatttg tacattatat ctctcagctt atttaaattt
     1321 agtatatgaa aataaaggtt ttattattga tttgtgtatc actttaaaac atatcatttt
     1381 aaaattaaaa ttgaaaaaat cactcaatat gtagaaaaca tgaccactat taggatataa
     1441 taaatttaat agatttagta aaatatctag gaataacgtt ggaggaatgg cattatgaat
     1501 ttatctaaag aatatgttaa tttgtatgat aattatttga aatatataaa tgaagtaagc
     1561 aaagagatta gaagtataaa gagtatgaaa aaacgtgttt taaaaagggg agattttgct
     1621 ccagaaaatg aagtattaga attggaagga aaaacaatac gtgatataga tgatgtagat
     1681 acaaaaaaac cgaaaaataa aatatataaa ttttcaaatg gggatgtata tatagggaaa
     1741 ttcttagagg gaaagatgga ggggaaaggc tcatatactt tttttgtaga tgaaggaacg
     1801 gctatggagt acataggaga atttaaagaa gacaaaaaaa acggaaaagg aaactttgta
     1861 ttttcaaatg gaaatgaata tataggctat tttgaggaag atatgatgaa tggtattgga
     1921 aatatgttat ataatagcaa agatgaatat attggaactt ggaaaaatgg aaaaaaagat
     1981 ggaaaaggta tttataagtg gagtgatgga tgtatatatg caggtgaatt taaaggtggg
     2041 aagatggaag gatatggcat ctgttataat agtaaaggtg aaatccttta tgaaggagaa
     2101 tggaagaata atttgattca tggtaaggga acttatatat gggaaaaagg taaaaaatat
     2161 ataggtgaat ttatgcatgg taaaaaacat gggcaaggaa ctttttatct aaataatgaa
     2221 ttggtttatg aagggacttg gaaatttgat aagccatcta tatttgatag aacattagat
     2281 gaaatatttt ccttgaggct gtagctttat ctaattagat aaagcttttt tctaatactt
     2341 actgtaaata ggtatgaatg atattgatta gtatacacta tcaatattag cctaataaat
     2401 gtaatattaa aaaattttga ttgattttaa aaaggagaga tatattgaag aaattaattg
     2461 ctttagtgtt agtaatactt attgttttat tttatagccc tgaattgtta aaagaaggaa
     2521 atgatttaaa agaaaagttt tttcaaagtg aaatatggaa tgaattttta gataaaataa
     2581 atataaatga taattctaag aaagataaaa aagaaaaaaa tcaaaatgta caatcaaata
     2641 atactgaagg ggataattta ggagagtcag acataaagaa ttttgaaaaa ataagtttag
     2701 aagacaattt aagctatgtt ttatcaagta ttggtaaacc tggtagaatt gatactagtg
     2761 aatatggttt tgattggtat gtatataatc aatatggaaa agaatttgca atggttggag
     2821 ttgaaaatga tgaagtagta gcactttata gcaattctat taattcatct gaaaatcaag
     2881 gtataaaaat aaatcaagat agacagacag tgagaactaa gattacaccg ttaaagtata
     2941 agagaaaagg aaataccaga tatataataa actcagaaaa tcaatatgat ataataagta
     3001 aagaaggtaa gtacattaca attttctacg atattcatga aaaaaataga gtttgttcat
     3061 atttaataat tgataaaagt accgaagatg agtttaaaaa attatatcca gatgatagag
     3121 aagagcttaa aaaatgtttt gaacttgaag ttatagacct tgtaaatagt gttagaaatc
     3181 aaagaggatt aaattcactg agatacagtg aacaggcaac tttgagttca agaaaacata
     3241 gtgaagatat gagagataat aatttttttg accatgtaaa caagaagaat gaaactccat
     3301 ttgacagaat gaaaagagaa gggatagtat atacttcagc tggagaaaac atagcagcag
     3361 gacagattaa tgcaatatat gcacatgaag cttggatgaa ctctgaagga catagaaaaa
     3421 atattttggg gaattataat aatattggag ttggagtaat atttggagga agctataaaa
     3481 catattacac tcaaaatttt tataaataac taaaatattt gaaaggaagt ttaaaaatga
     3541 catcatggaa aaaaaagaca gtatataagt gtttaatagc agtagtcttg ttttgtggaa
     3601 taatattaat atctaatttt agcaaagttt ctgctttgat gacggatact agtggaaatg
     3661 ttttgattaa acatggttca agagaaaaaa agttaatagc aattaccttt gatgatggtc
     3721 ctcatcctaa agaaactagt caagttttag atgtgttaaa gaaatacaat gtaaaagcta
     3781 ccttttttat agctggaaaa catgcaaaat ggtataaaga accattagta agagcaagta
     3841 aagaaggtca cgagatagga aatcatactt tcaatcatcc tgatataagt aatttaagtt
     3901 ctagtcagat agaagaggag attgttaagt gtgaagacat tttgaaagaa gtaactggaa
     3961 aaaaacctac attatttaga ccaccatttg gaagttatag agaaaaagaa ttaatagaaa
     4021 ttgcaaagaa gcatgactat aaagttgttt tatggacagg cgtagatgtg aaagattgga
     4081 aaaatccagg agctaatagc attgcagata aaataattaa taaagtacaa aatggagata
     4141 taatactttt acatgattat gcaactaatg atacagttga agctttagat atgtttatcc
     4201 caaaaatgat tgaaaaaggc ttcaaatttg taacagtttc tgagttaata aaataatttt
     4261 tagggggaga tttacagtat gattcttatg atagacaatt atgattcttt tgtatacaac
     4321 ctagtacaat atatagaaga attaggggaa acagttgtag taaaaagaaa taatgaaatt
     4381 aaaataaggg acattgaaga gctaaatcca gaggtaattg tgttatctcc aggaccatgc
     4441 tctccaaaag aagctggtat ttgtatagat attgttgagt attttaaggg gaaaaaacct
     4501 atactaggaa tttgtttagg tcaccaaact attggacatg tttttggagg agatattata
     4561 aaagctcaac agcctgtgca tggaaaagta tatagtatta gtcatactaa taaaggagtt
     4621 tttagggggc ttaaaaaccc tttaaatgta actaggtatc attcactaat aattgattcc
     4681 aatacagttc caaaagaact agaagttaca gccactactg ataaagggga aataatggga
     4741 attagacata agaaatattt aatagaagga gtacagtttc atccagaagc tattttgtca
     4801 gagtatggtc atgaaatgct taaaaacttt ataatagaag ctagagaaag ggtacatatg
     4861 taatatgata agagagataa atactacact aaattctttt gagatattta ctatttttag
     4921 aaatgaacat gacagtttta tattagacag tgctatggat aaagaaaaat tgggaagata
     4981 ttcttttata agtagccaac cattcaaggt attaaaatat aaggatactg atgaaaatcc
     5041 tttagaagtt ttaaaagaag aactacataa atatagagtt ataaatgaca ctaatcttcc
     5101 atttgtagga ggtgctgtgg gatatttatc ctatgattta ggtaattaca tagaaacttt
     5161 acctagaact gctatagatg atattaagat gcctgatatg tattttggat tttataatca
     5221 tgtaatagtt atagaccatc ttgtgcaaaa aacttatata gctactccaa acatagatat
     5281 aaaattagaa gaaaagataa tggatgatat agaacaaaga atattaaaag aagaaaaaaa
     5341 aggcatagat agtatatgtt atgaagaaaa agaagtaaca cctataagac ttaaatctaa
     5401 ctttacaaag gaagaattta aaaatgcagt tcaaagtgtt agagagtaca taagacaagg
     5461 agatatatat caagctaatt taacacaaag attcagtgga gaaacagaac ttacaagctt
     5521 tgaattgtat agggatctaa gaagatttag cccagctcca tttggagcat tcttaaattt
     5581 tgaagacaca catatattat caaattctcc agaaagattt ataagatgtg ttaataatag
     5641 aatagaaact agaccaataa aaggtactcg tccaagaggt aaaaataaag aagaagattt
     5701 aaaacttcaa caagaactta gaaatagtga aaaagacaga gctgaactgc ttatgatagt
     5761 agatttagaa agaaatgata ttggaagaat atctaaaact ggaagtgtta aagttccaga
     5821 actatttgta attgaaccat atgcaaatgt aaatcactta gtttccacag ttgtaggtga
     5881 gttaaaagat ggcaaagatg ctactgatgt aataaaagca acttttccag gggggtctat
     5941 aacaggagca cctaagatta gagcaatgga aattatagat gaattagagc caacacaaag
     6001 aaatgtatat actggttcaa taggttatat aggttttaat ggtgatatgg attttaatat
     6061 agcaattaga acaataatca aaaatgacaa aaaagtctat tttcaagttg gaggaggtat
     6121 gacttgggat tctgacccag atgaagaata tcaagaaaca cttgataaag caaaatctat
     6181 aatgaaggct ttgaggggat attatgaaga ataatgtagg ttttgatagt agtttaagta
     6241 aatttggaat tggtttgttt gaaactatta aagttaaaaa tggattacca atagatttaa
     6301 atatccatgt agaaagaatg ctaagttcaa taaattgttt ggatttagat ataaattata
     6361 aaaaagattt cttgataaat gaaattgtta catatataaa aaaagaaaat gttattgata
     6421 aagcacttag aattaccgtt tttgatgaag gttataatat atctattagg gatattccat
     6481 ataatcaaga gatgtatgaa aaggggttta gattaactat atcaccgata gttaggggga
     6541 atagtttaat tcatagacat aagactacta actattttga aaatatatat accaaaaata
     6601 tcgcaaataa gactggttat aatgatggta tatttttaaa ctcagaaggt gtaatattag
     6661 aatgttctat gagcaatatc ttctttataa aaggagaaag agtgtacact cctagtgata
     6721 gattgccaat attaaatgga ataataaaaa aaaggattat agagatttgt gacgaattac
     6781 atatagagtt gatagaaaat gaaattaata tatcagaaat tagtagtttt gattttgttt
     6841 ttgtcacaaa tagtcttatg ggcgctataa aggttacaga aattgacaaa ataaaattta
     6901 ataaagaaaa tgttgttttt gataaaatag aggagttatt agaataaatt aaaatattaa
     6961 caatttgttg gagacaaaag atgataggct gtatttatga agtatacaat gaagagataa
     7021 gtaaaataat agaaaaccaa aatactttgg ctgtatattt ggtgggttct agtaaagatg
     7081 tagattttac tctttatgat gtagaaataa acgatattga tgtattcgtt tttgtaaaag
     7141 aaggggaaaa acaagagaga atactattta aaaaaaaggg aatagaattt gatataaatt
     7201 acttttcaaa agatggtata aaaaaattat tatcaaatag ggaatacttt tttgtgaaag
     7261 aaatgaaaga tgctaaagta ctgtttgata gggaaaatat atcacatact ataaaagata
     7321 taagtagaga tatttactta gaaggaccta gtaaaatgtc attagaggaa aagtctttta
     7381 taaagcaaga tattggagca aaaatatcga atttaaaaaa taaagaaaaa tttgatgttt
     7441 ttgaatatca ttttttgacg aatttatatt taaaagatat aataattggg tactttaata
     7501 taaatgataa atgggtacca aaagataaaa aattgctaaa agttttaaaa aaagaaaata
     7561 atgagctttt tgaactagtg tcaaaagtaa gtgaaaatta tgactatcaa agacttttag
     7621 atgtttataa ttatattttt aaagaaattg agacaaaaga ggttataaaa ctaatcttct
     7681 agtcacaaat caatgggggg agtttaaatg aataaagttg ataaagaaaa gatacaacat
     7741 gcagtaagag aaatattaga ggcaattggg gaagacccag atagagaagg tctaatcgag
     7801 actccaaata gagttgctag gatgtatgaa gagatattct ctggtcttaa tgaagaacca
     7861 agagaccatt taaaagttct ttttgcagat gaaaaacatg aagaattagt gttggtaaaa
     7921 gatattccat tttattcgtg ctgtgagcat catctagttc ctttctttgg aaaggctcat
     7981 attgcttact taccaaaagg aggaagactt acaggtcttt ctaaacttgc tagagtaata
     8041 gatacattgg caaaaagacc gcaattacaa gaacgaatca ctaaaaatgc tgcagatata
     8101 ataatggaag aattacaacc ttatggtgtc ttagtagtag tagaagctga acatatgtgc
     8161 atgacaatga gaggtgtaaa aaaaccaggt tcaaaaactg ttacatcagc agtgagaggt
     8221 atatttgaaa aggacattgc gtctagagct gaagctatga gtttgattac tatgaagtag
     8281 caatttatta tatatagaat catttattga gatatgaaat ttaatttaag ggagtgtcat
     8341 taattgtgtt tgattatggt aaaagaactt atataatggg aatattaaat gtaactccag
     8401 atagtttttc tgatggagga gattttaata acttagacat agcaatacaa catgcaaaag
     8461 acatggttga ccaaggtgca gatataatag acttaggagg agagtctaca cgtccaggtc
     8521 atagctatgt ggattcagat gaagagttaa gaagagtaat ccctgtaata aaaaaactta
     8581 aacaggaatt ggatatacca atatcaatag acacttataa ggcagatgtt gcagaagaag
     8641 ccttaaaact aggtgttact atggtaaatg atgtttgggg tcttagaaaa gataaaaata
     8701 tggcttctgt aataggaaaa tatgatgcag aagtgtgtat aatgcataat caagatggga
     8761 caaactatga caaagatata atggagtcaa taaaagattt ttttaagata agtatagaaa
     8821 tggcaataag ttgtggtgta aaaaaagaaa aaatagtact tgacccaggt ataggatttg
     8881 gcaaggattt tgaacaaaat attgaagtat taagaagatt aaatgaatta aaagatttag
     8941 ggtatcctat tttgcttggg acatctagaa aatcagtaat aggaaaagta cttccagttg
     9001 agcctaaaaa aaggttagaa ggtacaatag ctactactgt tcttggtata agagatggtg
     9061 tagatatagt tagagtacat gacgtttatg aaaatttaat ggcagctaga atgactgatg
     9121 caatatatag aaagtaggta taatataatg gataaaatat tacttagtaa tttaggattc
     9181 tatggatatc atggtgttct taaagaagaa aattttctag gtcagaaatt ctttgttgac
     9241 atggaacttt atattgattc aagagaagca ggtcttagtg acgatataaa taaatctgta
     9301 agctatgctg aggtttacga tgttgttaaa gatattactg aaaataaaca atttaatctt
     9361 ttggaggctt tggcagaaaa tattgctgaa gaagtcttga ataaatttat acttataaat
     9421 ggagttatgg tcagagttag aaagcctgaa gctcctgtaa atggtattta tgactatttt
     9481 ggtgttgaga taaggagaac aagagatgaa taaggcttat ttgggaatag gtactaacat
     9541 gggtgataga tttgataatt tatcaagagc atgtgaactt ttgaaaaaca gcgattctat
     9601 atataaggta aaagaatcaa gtttatacga aacaaaacca tggggttata cagaacaagc
     9661 agattttcta aatatgtgtg tagaaataga aacagagttt gagccttatg agttgttaga
     9721 atattgtcaa gaaatagaga gaaaactaca cagagaaaga atagttcatt ggggaccaag
     9781 aactatagat gtagatatac tattttttaa tgatgtagtt tccactgatg aaagactaat
     9841 aatacctcac ccaaggattc aagatagagc tttcgttttg ataccactta tggatttaaa
     9901 tgaagaactt ataataaatg aaaaaacaat aaaagaacat ttaaacctcc tatctgctga
     9961 agaaagagat gaagtaaagg agcttgtagg ttatgaaaga aaacctattt aataataatt
    10021 caaagataga gataaacaca aataacaaaa agataactgt aaaaaaggat aaacttataa
    10081 tagctggacc atgtgcaata gagagttatg agcaactttt ggagacggct aaatttgtaa
    10141 aaagtcaggg agcaaatatt ttaagaggtg gagcgtacaa gccaagaaca tcaccaaatt
    10201 catttcaagg attaaaaaaa gaaggtcttg aaatattaaa agcggttaaa gatgaagttg
    10261 gtatggctgt tattacagaa cttatggatg taagagatat ggacgaattg tatagtataa
    10321 gtgatataat tcaaattggg tcaagaaata tgcaaaactt tactctttta agtgaagtgg
    10381 gaaaacaaaa taaacctgtt atgttaaaaa gaggaatagc atccacaatt actgaatgga
    10441 taggtgcttc tgaatatata gcaatagaag gaaatagtaa tattataatg tgtgagagag
    10501 gtataagaac atataatgat tatactagaa atacattgga tttagctgca gtacccatta
    10561 ttcaaaagga aacaggtctt cctgttgtgg tagacccaag tcatgctact ggagttaggt
    10621 atttggtaaa acctatgtca ctggcatctt ttgcatgtgg agcagatgga ataatggtag
    10681 aagtgcatcc tgacccagaa aatgctttgt cagatggtgc tcaatctctt tgttttaatg
    10741 aatttgaaga tttaatgaaa tcaattaata attattaaaa gaggcatgag cctctttttt
    10801 attcgtaatc gttattaagg taaatttata agttataatt tgatggttat attatttatt
    10861 ataaataaag atttaatatt gatagaatta atataaaaaa taaaaatttt ttgattaata
    10921 agaaggatat caataaaaaa agtcgaattg tgtatattga gtgattgaca aatttagaat
    10981 atagtgtaga atagaaatgt taacacaaaa aattacacca gaaggtgata atatgaatga
    11041 tataaaagac attattgaag aaataaaagc tagatgcgat atagcaagta taatatctga
    11101 atatatgagt ataaaacaat ctggagctaa ttacaaagga ttatgcccat ttcatggcga
    11161 aaagacacca tctttttata taaatacatc aaaacagatt tataagtgtt tcggttgtgg
    11221 tgaaggtgga gatataataa attttgtcat gaaaatggaa aatttagatt ttatggatgc
    11281 tgtaaaaatt ttagcaaata aatgcggtat agaaattaac actaacatga atgaagaaac
    11341 tagaattaaa atagaaaaat ctaagaaatt tcaagatatt cacacagaag cagctagatt
    11401 ttatctttca aacttattgg gaagcaaaaa tcttgggtat gaatatttaa gaataagagg
    11461 actagatgat aaaattatta agaagtttgg tttaggattt tctttagatt catggaattc
    11521 acttatgaat actctaatca gtaaaggata taaaaaacaa gacttattgg agtgcggtct
    11581 aattgcaaaa aatagagatg gaactaattg ctatgataaa tttaggaata gagttatgtt
    11641 tcctatattc gattatagag gaaacataat agggtttggg ggaagagtat tagacgattc
    11701 tttgccaaaa tacttaaatt ctccagacac attaattttt aataaaaaac agaacttata
    11761 cggattaaat tttgctagaa aaaatttaga aagtaaaact atagtcttag ttgaaggata
    11821 tatggattta atttcgcttt atcagtatgg tataaaaaat gtagtagcaa cccttggaac
    11881 agccttgact gaacaacaag gccttttaat aaagagatat gcggacactg ctattatatc
    11941 ttatgattct gatgaagcag gaataaaagc gactttaaga gctatagaca tacttactaa
    12001 attaggtatc aatgtaaaag tgttggactt aaaagatgct aaagacccag atgaatttgt
    12061 aagaaaatac ggacttagtg attataaaaa agctatggat gtttctactc actacataaa
    12121 atataaaata gatcatctta aaaaagaatt taatattcaa aaagatgaag aacgagtgaa
    12181 gttcgcaaaa gaagcttcta aaattataaa acaattgaca agtcctgttg aaattgattt
    12241 ttatacaaag tatttaagca atcaaataga tattaatgtc gagtctataa agagagaagt
    12301 ctatggtaaa aattacaata agccatataa taacaaaaat caaaagaaaa tagaagaaaa
    12361 agtaattgaa aaagtcgaag tcagacaaga cggaaaacaa ttagttgaag aaactctaat
    12421 aaaaataatg ttagaagaca aaaaaattag agaaatagcg ttacttaaag tagaagaaag
    12481 tgatttttta ttgaaagaaa gtaaagaaat tttaaattac atgattaaaa atcaagaatt
    12541 ggacaaaata actattgaca aattgaaaag tttaaacata tccgaagaat acttaaaaga
    12601 attaaattca atttctttga atagtataaa cttagagaat acaaaagaaa tagaaggaat
    12661 aataacaaat atcagaaaaa actcattaga agagcaaatt aatagcttgt tgagagaaca
    12721 acaagaatta gaaaataata atgatatgaa agaggtagat ggtagagtta tggaaattgc
    12781 tttaaaaata gttgagataa ataaaatttt aaagagcttg tagagaaagg aggtttgagt
    12841 gtggaaaata aatcgaataa aaaagagtta aaaaaggtta ctgctaagac attaatagaa
    12901 aaaggaaaaa agcaaggttc tctgacactt gcagagataa tggaagcttt ttcggagact
    12961 gaacttgata aggatcaagt agaaaatctt tatgagactt tgggaaattt gggaatagaa
    13021 ataacagaaa caaaaaatta taaagctgat atagattttt cggttgctga tgacgattta
    13081 agtataggcc acttagatga agatgcagaa gcaatttcac atgaggactc ttctgcaata
    13141 gaaatagaaa ctgtggattt atctttacca aaagggataa gtatagatga ccctgtaaga
    13201 atgtacttaa aagaaatagg aaaaattcct ctacttaaac cacatgaaga agtagaattt
    13261 gctagaagaa tgcacgaagg tgatgagata gcaaaacaaa ggttagttga agcaaactta
    13321 aggctagttg taagtatagc aaaaagatat gtaggaagag gtatgctttt cttagattta
    13381 atacaagagg gaaatttagg tcttataaaa gcagtcgaaa aatttgacta cacaaaagga
    13441 tataagttta gtacttacgc aacatggtgg ataagacaag ctataacacg tgctattgca
    13501 gaccaagcta gaactataag aataccagtt catatggtag agactataaa taagctaata
    13561 agagtatcaa gacaactact tcaagaactt ggaagagatc caaagccaga agaaattgca
    13621 aaagaaatgg aaatgacaga agacaaagta agagaaataa tgaaaatagc tcaagaccct
    13681 gtgtctttag aaacaccaat aggagaagaa gaagatagtc atttaggtga ttttattcca
    13741 gatgatgatg ctccagcccc agcagaggca gcagcatatt ctttattaaa agaacaaata
    13801 gaagatgtac ttggttcatt aaatgataga gagcaaaaag tattaaagct tagatttgga
    13861 cttgaggatg gtagagctag aactcttgag gaagttggaa aagagtttga tgtaactaga
    13921 gagagaataa gacaaataga agcaaaagca ttaagaaaac taagacatcc aagtagatca
    13981 aaaaaactta gagattattt agactaaaaa gatacatcat taatgttttt gtgataaatg
    14041 ccatgagata agtgatatct catggctatt ttgtagtaaa gatttaattt tggttttgta
    14101 gttatttcag tcttatctat aacttagtta aattatatgg ataaagtgaa ttgaaaggag
    14161 aattatattt gaaattaaca gatagattat tgaaaatagc atcattggtg tcagatggaa
    14221 aaaaaatagc tgatatagga acagaccatg gatacatacc agtatatttg ttaaaagagg
    14281 gaagagtacc atttgcagtg ttggcagacg ttaataaagg acctcttgac aatgcccata
    14341 aagaagtcat acagaacaat cttttagata aagttgattt acgattgggt tctggcatag
    14401 agattcttga aataggagaa gtagaagaag taataattgc tggtatgggt ggaattttga
    14461 taagtgagct tctcgaagct aaaaaagaag tagcacataa tgtagaaaaa ttaatattac
    14521 agccaatgca agcgcaagaa gaacttagat attacctttt aaacaatggt tatgaaattt
    14581 tagaagaagt tttagtgaga gaagatttta gaatatatga aataattgtt gccaaatata
    14641 caggtaaaaa tactataata gaagatgaga tatattatga ggttggaata aagcttttag
    14701 aaaacaagga ttctcttttt aaggatttta tagaaaaaaa gataaagaca tatagttcta
    14761 tagttagcaa attagaaggg aaaaatgggg aagctataga taagaagaga aatgaaagtg
    14821 aagttacgat aaaaaaactt gaaaatttaa taaaataaat aggaggaata tatgctatta
    14881 aagagtctaa ctagaaaaat tgaaaaaaaa taccctctaa acttagctga ggattgggat
    14941 aatgtaggtc ttatagttgg agattttgat atggatgtaa aaaaggtatt ggtatcttta
    15001 gaagctaatg aagatgttat tgatgaagct atatctaaaa atatagattt aattgtgaca
    15061 catcatcctt ttatatttgg gaaaattaat aaaattaata gtgcagattt aaaaggtagg
    15121 cttatccaaa aacttattaa aaataatgta tcactttatt ctatgcatac taattttgat
    15181 atagcatttg atggtttaaa tgactatttt atggaaatta tggaatttgg taattcaaag
    15241 gttttagacg taactaaaag cgaaaactta tataaattag cagtatacgt gccacataac
    15301 tattcagatg aacttagaaa ggttttaagt aattcaggag caggtcatat aggaaattat
    15361 agtgactgta cgttttcaat agaaggtgaa ggacaattta agccattaga aggctctaat
    15421 ccgtttcttg ggagtgtaaa tgatatagaa actgtaaatg aagttaaaat tgaaactgta
    15481 gtaccacaga agctcttagg tggggtaata agttctatgt tagatgcaca tccttatgaa
    15541 gaagttgcat atgatttgta caagttagaa aataaaggtg agatatttgg actaggtaga
    15601 ataagtaaac ttgataaaag tatgacatta gaaagtcttt caaagaaaat aaaagagaaa
    15661 ttaaatatga aacacatcag agtagttgga aatcttagta caaacataac gaaagtagct
    15721 gttgtaacag gagctggttc agagtttgta aaaaaagcta agagacaagg tgcagaagta
    15781 ctaattacag gtgatgtaaa gtatcatgag gcacaagatg cacttgatat tggtatgtgt
    15841 atagtggatt gtggtcattt tgatacagaa gatatattta aaaatgttat gaagagattt
    15901 ttagatgaaa ttagtgaaat tgaagtaata aaaagtagtg tatatttgaa tccatttagt
    15961 actatttagt agtacttgat taaaaaatag tatataaaaa ataaatttga gtttaattag
    16021 ggggataagg atgaaagcag cagtaatttt tcatagtgtt tgtgggagta catacttatt
    16081 agctagagaa tataaagaag cgcttaaaga aatgaatatt gaggtagata tctttagagt
    16141 aagtgacgaa gttgcaaaga cacttcctca atattattta ataaattcta aagaatacaa
    16201 agatgaattt gaaagtataa atgtaattaa atctggaaga gagctattag attatgatgc
    16261 tatatttatg ggttcaccaa catattacgg aaatgtatct ggaccaatga agatgtttat
    16321 ggatagtttt tctgatattt gggtaggtgc tcctttgagt ggtaaaatat ttggttgttt
    16381 tgctacagca ggttcacaac atggaggagg agaactagcc ttgcaagcta tgaatatatt
    16441 tgctcaacat atggggatga ctcttttatc agttccatgt tcaataagag gaggtcatcc
    16501 agcgtatggg atacttcata tagcaggaga taactctaat ataagaccaa gtgatgatgt
    16561 taaaataggt ataagagatt acctagaaag acttagtata taagaatact atataaaaat
    16621 acctaaaagt ggctgtatat acttttaggt atttttactt aattataaac gtgaagcttt
    16681 accagaaata tggtcaattt ctattttaac aacagttgtt aagttcacat ctttctctat
    16741 gtacttcatg ccttcttcaa agaatccttt agaatatttt tttattattt ctacaagagc
    16801 atttttcttt tcttcatttt ctacagtaca agctttccca aaaactatag cactagaata
    16861 agtagtacta aatttgtctg gaataacatt ttcattagca accactaaaa aagaaacttt
    16921 gttgtttttc aatatattat ctaacttatg accatttctt gcagagtgaa agtagataga
    16981 atcatcaaag tatacataat ttacagcaac tccataagga taaccatttt cagatatagt
    17041 ggaaaaagta ccaaattcac cattttttaa tacttcgata gtatcttctt ttgtcatttc
    17101 tcttttcttc aatctcattt ctttaaacat aatatcatcc tttctaattt tgatgcttaa
    17161 attaaatttt agagcatata taaatattat gctatgtttt ttataaattt taataagaaa
    17221 atatagttta agataaaagg ttgagaaaga gaatctattt gggggttcat ttatgtaatt
    17281 attgttagag tattaccaac aatattaata actttaatta atgacttgct gttatttaag
    17341 gtagcaagct tgtctataag aagggaaagt tatcgaggat agaagttata gtttataatg
    17401 atattataaa gaaaatgttg ttgtagaaaa taataaatag tagagaggta ttaagttgaa
    17461 tataatactt aatacctctt taaaattaaa ttataaaagt gttatggaaa ctgtactata
    17521 catggtaagg agataataaa gaatgtatct ttaaagtctc aaccaaacag caaaacttat
    17581 ccaacaaaca tacaataaat gcttctttgt atctaggagg cttgacagta agtggccaca
    17641 tgtgctttaa gattatgtcc gtttcttttt catttatttg aaaaaataaa gttgcatttt
    17701 tcaatgcttc tctagggtga gtaaatccat gtaatccttt tctatcacct ttgtaatgcc
    17761 aatcataaag aaaaaagtcg tgtaataaag cccctctaat aacactttga atatcaacat
    17821 ttagatgcaa ttttttacat aatagataac tataatatgc tactgataaa ctatgttcaa
    17881 gacatgaaac attgccatga tgaggaaatg ttctcataag ttgtactttt tctgaagaaa
    17941 gtatttcaga agcacattca ttaaaatatt tgatttcagc ttttgacaac attatacaaa
    18001 tctccatttc tagtaatata aatactatat ttcaacgata tatgaaatat ttcttatcct
    18061 acaaaatata atacccaata atacaagtaa gatacctttt atggtatttt aaagtaagag
    18121 agattttata aggctaaaca ataaaaaaat taaaagtaaa gctatagcaa tatatagtat
    18181 ttttccaaga ggattgccaa aatttatagt ccatccaata ccaaaccttt tattaaccat
    18241 caatgatggg tcatttggat tattatacat gattcccgct atccaatatt tttcattctc
    18301 ttctggagaa taagaagagt tcgattttaa atttggagaa ttaatgtatg ttgctattaa
    18361 ataaattata actaaaagcg ttgtaatatt catagcagtt gatagttttg ttttaattga
    18421 taaaatagta gtaaaaaact gtattgtcat tatagtcatc aatattaaaa acaaataacc
    18481 aatcttattt aaatattcaa tgttttcaat tctactttct ttaattctat ttgtatctat
    18541 cttaatcctt gactttatgg agccaataga agttatatat aataaaacca ttaaacaaaa
    18601 gttagtacca attaatttaa atacattaag aaatgattta tctataaaaa catcaggaga
    18661 cccatttatg ttccaatgag tggcaatgga gtctggcaat tgattataat taaatactat
    18721 aaaaatactc attccaaaag taaatagtat tggtattaaa tagattattt taaatttctt
    18781 tattatttta ttttttttat ttataaaatc catatctatt attaattttg aatctacatc
    18841 tatatgacct aatttagaat aaagttctga tttaagattc ttagcttttt tatgtgtatg
    18901 aatatatagt atactttcat ataataaaaa aactatgata ctaataaaat aggaaagttc
    18961 caatttgtta aaagtaaaaa ccagaataaa aactaatata aggtctataa taaaacctaa
    19021 agacaacagg tttttaaatt ttttatctag ctttataaag tgattataat ttttatactc
    19081 ttggtctata gaaaccccat aaatgtgttt tttacctaca aaatagggca taaaataaaa
    19141 tgtagcatac atcaaaatta gaatcggaaa tattgtaaat aggcattcaa tcttactcat
    19201 aatatttcac ctcataattg tcaaataaac ttgaacttaa cgataaaaat tcctctttac
    19261 taatacctga taaataagat tttgccacta atagttccaa gtcaagctta tttttttgac
    19321 gagttgtgtt gtctattttc attggtaatt gagccacaat agcacctttt cttctatcaa
    19381 tatttaagaa tccctcttct tttaattcgt tgtaggattt gttaactgta tgtaaattta
    19441 caccaatatt ttcagccata cttcttacag atggaagtga ttcatttatt ttcaattctc
    19501 ctgaagctat agctttagtt atttcttctt taatttgtac ataaatagat ttatcgctat
    19561 taaaatctaa atttaaaacc ataaaaaacc tccattatgc tttataaatg aaaacgattg
    19621 ttatatacat agtataacat aaaaaataat aacaaacaca aaatttaaat ttatattttg
    19681 taaaaattgt aatttaaaaa ataacataat ttttattaaa ataatacaga tactatttat
    19741 agatagaaat aaaaattaga aaggagaaaa aatatgttaa catatttaat gaaaagacaa
    19801 atgcataaaa aagatgatgg aatgagtaaa ccaatgatgc ttacaggagc tgtacttaca
    19861 ggtgtaggag catatgctgt atacaaaatg ataaaaaatc gtaaatctaa ttctcaaatg
    19921 gtcaatacaa attattatgg aaatagcgat tatgatgatt ataaatatga cgaatttgat
    19981 tatgactgtg actgtagaga tacaaaacag gattatgaat atgaagaatt aaaaaaaaaa
    20041 gtaaaagaat ttaattcaag aagaataaat tgtgaaaatt gtccacatgt ttctcaagaa
    20101 gaaatgatgc aatatgtaaa tagtgttaaa gatgtaaagg atgatgttga tttacatgaa
    20161 gatgctaaaa aagataatat ttacaaagaa gatgaataca aaaaatatga agaagaataa
    20221 gtaatattct gtataatcaa acaaatagta atattaaact atttaatatc tagtttctaa
    20281 tatgtaagtt gtaacttagc ttgaaagaat cggtatcatt ctttagagag ttaagtaaca
    20341 acttacattt tgtttttata aattcgaatg gctctttgtg actattttgt aattttagat
    20401 atattttagt atcaagggta attgtgtata ataaaacttg tatatgcaga tagtttaaaa
    20461 ttaaaatgaa aagaaaggaa atagttatgg taaagttgtt aatagttgaa gatgatagta
    20521 ctatctcttt tggaataaag tatgctttag aacaagaagg atttagtata gatatatcaa
    20581 aagatttatc cagtggaaaa gaaatgattt cttctaatga atatagcttg atattgttgg
    20641 atgttacatt accagatgga actggttacg agctttgtca atatataaga ggattttctc
    20701 agattcctat aatattcctg actgcttgtg atgaagaagt aaatattgta atgggtcttg
    20761 atataggcgg agacgattat ataacaaagc cctttagaat tagagaatta atatctagaa
    20821 taaaagctgt tttaagaaga aaagccaata ctgtagaaga aagtaagaaa atacttaagt
    20881 ttggagattt aagtatatat acattggaag ctagagtata taaaaacgat aaagaagtat
    20941 ttctgacatc agttgaatat aaacttcttt taattcttat acagaataaa aatactgtgt
    21001 taagtagaac tcaaatattg gaaaaacttt gggatgtaac ttatgatttt gtaaatgaca
    21061 atactctaac agtttatata aaaaggctta gagaaaaaat aggtgatgat ttatgtgaac
    21121 caatctacat agaaactgta aggggtcttg gttataaatg gataggaagt gaaaatagtg
    21181 tttctatata atccggaagt gaagaagttt ttaagtaagt atgttacttt gatatttgtt
    21241 attattatca tatctattgg atttagtgta atcaatgtat ctttaactaa agatatgatt
    21301 gtaagaaata atcaggctat aataggaact ctatcaagta agtatccaaa cttagaaagt
    21361 gagatagtag atataataac tcaaggaaag tctatggaaa atacagatta tggtaagaaa
    21421 atattaagta agtataatta tgataaatct attaggataa actctgagcc tattatttct
    21481 aaattagttt tagatactat caaaataaat ataatattag tatgtataat atttattttg
    21541 atatttgtgt tggttgttag atattttaag tcaatttaca atgatttatc agatatgact
    21601 aaatatgttt actatagttc agagggcaag tcatttgata tgaaaaataa gaatcaagaa
    21661 gggcagatag gtcttttaaa aactgaacta ttaaagatga caacaattct taatgaaaag
    21721 gttgaactgt taaaaacaga aaagatattt ttaaacaata caatttccga tatatcacat
    21781 caattaaaaa ctccaatgac ttctttaata atgttgaatg atttattata taatgatata
    21841 ccatatgaag taaaaatcga ttttttgaat aagataaaaa atcaattaaa tagaatggat
    21901 tggttgatta aaagcatgct taaattatca aaggtagaag caaaagtgat aaattttaaa
    21961 aaggataagg tgaaatttag tgaactcata catagagcaa tgcaatctat gaaaatacct
    22021 atggagatta aaaatcaaaa actgactata gagggaagcg ataatatatc ttatattggt
    22081 gatattgatt ggtctgtgga agcattagtg aatataatca aaaactgtgt agaacatact
    22141 cctgagtttg gaaatataac tataacctat aaagaaaacc cattattttc tgaactaata
    22201 ataaaagatg atggtgaagg tatacataaa aaagatatac cacatgtatt taaacgattc
    22261 tatagaggaa gaagtagttc aaaagaagat agtgtaggaa taggtcttgc aatgtcaaaa
    22321 tctataatag aaagccaaaa tggcgatata tatgtaaaca gcgaaaaagg taagggtaca
    22381 gaatttcata taatatttca taaaatgtat gatagtgact aatctgtaat atttaattca
    22441 ctttatagta atagccaaag cctaatatat gaagtataga atataaatat tggaggtagt
    22501 tatggaagtt ttaagagtag aaaatctaac taaaagttat ggtaaaaatg aaacaaaagt
    22561 tgatgctata aaaaatgtaa gtttatcagt tgaaaaagga acatttatag caataacagg
    22621 tccaagtgga agtggtaaaa gtaccttatt acatttactg ggaggagttg atagaccaac
    22681 tagtggtaag gtttatataa atgatgttga tatatataat ttaaaaacta aggacttggc
    22741 aatatttaga agaagaaata taggtcttat atatcaattt tacaacttaa ttccagtctt
    22801 aaatgttaag gaaaatatat tgcttccagc agagcttgac aatagagata ttgatagaga
    22861 atattttgat gatttaatga aaacattagg tctaaatgat agggaaaagc accttccaaa
    22921 ccaattatca ggaggtcagc aacagagaac ctctataggg cgtgcattga ttaatagacc
    22981 ttctataata ttagcagatg agccaacagg taatttagat agtaaaaatt caaaagaaat
    23041 actagaattg ttaaaattat cagtaaagaa atacaatcag acactaataa tgataactca
    23101 tgacaaaaat atggcacttc aagcagatag aattataagc atagaagatg gaatcataaa
    23161 aagtgatgag gtgatgtaga tgaatttgta tacatcacta actattagat acctaaaaca
    23221 aaataaaaga agaaccattg taactataat cgggataata ctttcgacag ctttaatttg
    23281 tggtatagga aacatatttg aaagttttat ggattatcaa gtgagagaaa ctataaagaa
    23341 tgatggaagt ttccatgtta cattttatga tgtaaataga aagaatgtgg agtatgtaac
    23401 gaaatcagct gaagtagaaa aatatgcatt taccaaacag cttggatatt ctaaattaga
    23461 aaatagtgaa aatggtatag taagtataaa gcaatatgat aaaaatgcaa taaacggata
    23521 taaaatttct ataaaagaag gtagatttcc agctaaggaa ggagaaattg ttctaagtga
    23581 aaatattatt aatcttatag atgataactt aaaaataggg gataagataa ctttaaaagt
    23641 aggagatatg tttgattcaa gtaagaagaa gattgatagt atggtatttc atgaggggga
    23701 ttatatagca agtgaaaagg atagaacttt tgaagttgtt ggtataatta aaaaacctgg
    23761 atttgaacgt tataatggaa ttgcaactgc tataacttat tttaatccta tggataatta
    23821 caatgataca attaatgtat ccgtagaagt aagaaatcct aaagaggtgt atgaagtaag
    23881 taataaaata agcaaaaata tatattcaaa taaagataaa gaagcagttt ctgatatgat
    23941 aaaatacaat gaacatttat tgaggttaca aggtgctagt aagtatgcag atataaatag
    24001 ctctataaaa tctatcatta tagcagtaac tattttagta atcatatgta caattgctac
    24061 agtgtataat tcctttagta tttctataac tgaacgaaaa aaacagtttg ggatattaaa
    24121 ttccataggt gctacatcta gtcaaattaa aagattagtt tttatagaag gtattataat
    24181 tagtttaatt ggtataccaa taggactaat atctggaaca gtagccatag acttattatt
    24241 taaaattata aataagtatt ttactgaatc ggttgttact cagatgagtt tacggatagt
    24301 gtataatcca ataataatta ttgttagtat aataatagtt ttgtttacaa tctttatatc
    24361 aattttatta cctgcaatat cagcttctaa tatttcgcca cttaatgtga ttaaaaatac
    24421 tggagagtat aaagtgagaa aaatcaaaag ctcaagactt attaaaatga tttttaaaac
    24481 tgaaggagta cttgcatata aaaatattag gagaaataga aaaaaattta tagtaactct
    24541 tttttcttta atgataagtg taataatatt tatatctttt agtggattta cattactttt
    24601 actaagaagt gaagaaatta gaaattctca aagaaaatat gatttatatt taactgcaaa
    24661 gggaacagct aggtctatag atgatactgt aagcgaacta gaaggtattg atgggataaa
    24721 aaactttgaa ttggcaacag gacaatatgt ttctataaga gtaagtgaaa ataaaataaa
    24781 taaatccaag gaagatttaa ttgggaaata ttatcaaaaa tataaggttg gagatagtta
    24841 tgaatatgat ttcagtaata atgatttaat ttttccagga gattttgcaa taagaaataa
    24901 aataaataac ttaatacagg gttcttttaa taaggagaga gcaattcaag agaatggtgt
    24961 tatattagtt agaaaaagct catttgaatc aaagggtaag aaaggtgtag tagaacttac
    25021 caactacaaa gtaggagata cagtaacttg tgaatatctt gatgaaaatg cctcaagtaa
    25081 aaaaataaag gttaagattc ttgctataac tgatgaagaa cgtttaggta tgggttatca
    25141 aaatatggga ttacaattta taacttatga tgaagttgct aaaaatttaa acctaaagtt
    25201 aagtaaaagt cttatattta ttgattcagg aggaagcatt aagactaaga aggaaataga
    25261 agctttggct aataaaaata attttaactt ctatgatgaa agtgcaatta ctgaaagcga
    25321 aaaacaaaat ctaaaagtta ttaaaatatt tgtatatggc tttatagcag taatatcttt
    25381 agtaagtgtt acaaatattc taaatacagt aagcacaagt ataaatctaa gaaaaggaga
    25441 acttgcagta atacaatcta taggggttac tcctaaaggt tttagaaaaa tgatatattt
    25501 agaaagtttt atatatggta tactgtcatt gttgtttggg ataccgatta gtattggtat
    25561 gactctaatt atgaataaac ttatttcagg tgtaattgag ttttctccga ttataccatg
    25621 gacagcaata gttatatgta tagtaagtgt ttttataata acttttatag caggttatat
    25681 accaataagt aaattgaata aagaaaatat aatagataat ataagaagag aaagtatata
    25741 gatataaaga taatttttaa ctatataaaa tattattaaa atcat
//
LOCUS       DAMKOJ010000053        24417 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000053 DAMKOJ010000000
VERSION     DAMKOJ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.055"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            190..1023
                     /locus_tag="PC592_002382"
     CDS             190..1023
                     /locus_tag="PC592_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF4056345.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFVVVGARVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTATEVSKGPSKSSGKVAYITIDDGPSKFTDQIIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIIQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            1116..2048
                     /locus_tag="PC592_002383"
     CDS             1116..2048
                     /locus_tag="PC592_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF4056346.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKEYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEISASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFSKDDKNAEFTKEVFKLKKNEVSKVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            2100..2582
                     /locus_tag="PC592_002384"
     CDS             2100..2582
                     /locus_tag="PC592_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4056347.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILIRTSIDFIRKNRKYNNMTDIDLVDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            2594..3463
                     /locus_tag="PC592_002385"
     CDS             2594..3463
                     /locus_tag="PC592_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF4056348.1"
                     /translation="MTSKERLNKLKEEYHKIPIPKKLDTIINHEKIENIYQEKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFEERMEKIQSSKNKGHKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKRDSTKFYFIDQKKELPVEDFKTINKYQDFYFNKNEELVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            3691..4254
                     /locus_tag="PC592_002386"
                     /pseudo
     CDS             3691..4254
                     /locus_tag="PC592_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429797.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
     gene            4296..5117
                     /gene="xdhC"
                     /locus_tag="PC592_002387"
     CDS             4296..5117
                     /gene="xdhC"
                     /locus_tag="PC592_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory protein XdhC"
                     /protein_id="HDF4056349.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVIVLDSFEEIPDFPTDENSYIIILTRGHLYDSSALEWALKRDAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSRVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            5122..5883
                     /locus_tag="PC592_002388"
     CDS             5122..5883
                     /locus_tag="PC592_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDF4056350.1"
                     /translation="MNIGSKDSDILNVNFRGIDIKVILVYKNRKNISIKIDPFGKVIV
                     MSPPKMSKKIIKDIIIEKGDWILKKSEKYKGREEVYEQRMFITGEKFLYLGEEYHLVI
                     KEMLKDSVKKSNCKITINEYEIIVQTNDTSTDFIKKSLKSWYKIESERLVLERIDFLK
                     LNYEIMNQLVPASVKVKEQKKRWGSCTSQKNIYINSKISMAKLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKITI"
     misc_binding    6044..6300
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6413..6652
                     /locus_tag="PC592_002389"
     CDS             6413..6652
                     /locus_tag="PC592_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF4056351.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMKH"
     gene            6931..7926
                     /gene="ilvC"
                     /locus_tag="PC592_002390"
     CDS             6931..7926
                     /gene="ilvC"
                     /locus_tag="PC592_002390"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDF4056352.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVY
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLIMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            7979..9667
                     /gene="ilvB"
                     /locus_tag="PC592_002391"
     CDS             7979..9667
                     /gene="ilvB"
                     /locus_tag="PC592_002391"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDF4056353.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFKVANSGRKGPVLVDVP
                     KDLFLAEMDFSDEDYDLCQIDDYIDYKSDFSLDDEINVKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEDILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLIGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGIQTDEFHPQSILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGAKVGNIDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNERYSQTDINENVDYVKLVNAY
                     KIDGYKISNMEELGKVLDVIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            9875..10552
                     /locus_tag="PC592_002392"
     CDS             9875..10552
                     /locus_tag="PC592_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF4056354.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDVNPPS
                     FEKPLKK"
     gene            10722..12758
                     /locus_tag="PC592_002393"
     CDS             10722..12758
                     /locus_tag="PC592_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HDF4056355.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNEEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITNKELYKEIAMKTIDYVVREMQDKDGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIDNLSKKV
                     FEYRKERTSLHKDDKILTSWNALMVVALTKAYSTLKNDMYLDYSNKCLDFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCIDLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNKLEEMSYKQ
                     LKLYVNNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLSAFKELISENFIPNTT
                     FLAKKYNEENTIIGFLNNYKLKEDKTSYYVCQSNSCSQPINNLQKLKDMILGVE"
     gene            complement(12965..13512)
                     /locus_tag="PC592_002394"
                     /pseudo
     CDS             complement(12965..13512)
                     /locus_tag="PC592_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            13794..14729
                     /locus_tag="PC592_002395"
     CDS             13794..14729
                     /locus_tag="PC592_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase"
                     /protein_id="HDF4056356.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKNPKAVVQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGRQGIILNLAHMIINREI
                     KKYGRRSRSNKINDLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLIQGLKEIEDKENLKKVPLDVPIYIISGDKDPIGKNSKGVLRLRDRYIKLGVKDVT
                     CKLYKGGRHELLNEINKEEVFEDVICWLNNKIGIL"
     gene            15093..15860
                     /locus_tag="PC592_002396"
     CDS             15093..15860
                     /locus_tag="PC592_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011590398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056357.1"
                     /translation="MSKILRVKNIKKYYKSRGNITKAIDNISFEVESGEYIGIMGASG
                     SGKTTLLNCISTIDKTTDGNIYIGNKDITTMNEDELSKFRREELGFIFQDFNLLDTLT
                     AHDNIALSLSINGVNSKEIDNKIKKIANKLGVYEILNKYPYEMSGGQKQRIACARAII
                     TNPSLILADEPTGALDSKSAKLFLENLEVLNRELKATILMVTHDAFTASYCKRILFIK
                     DGKIFNELVRGNNTRQEFFDRIIKVISVLGGDDKHVF"
     gene            15841..17970
                     /locus_tag="PC592_002397"
     CDS             15841..17970
                     /locus_tag="PC592_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056358.1"
                     /translation="MINMFFKKNKSRRSRNKRKNNYVSRVSSESFKKLALNNVKKSLK
                     NYLIYFITLVFGVIILYTFNSLDNDIAILSSNALLSSSISFVRGIVSIFSILVCIIFA
                     FLIIYANNYLMKQRKKEFGIYSILGMDRRDINKLMFREMMIIGIFSLIIGIIFGVFVS
                     KGLSIFALKMLGISSSGFSFSMLTTIKTIVFFGIVLLLVNKFNKKTIKKYKLIDLLNA
                     NKKNEVSVAKGKKSNLILFFLSIVAIVLAYIIPLKMKISTFILGICLILILVGIYLFF
                     MSVSDFIMLKIKKHRFIYYKNLNPFIVSQISSQIKTMSMSITMICMLLFSSLIVIPFG
                     ISFGKYLIDDLQEATPYDVTLSKLYMNGDNIVEYSTKKNDIDSKTPSLKDELIENGFP
                     LTSFSKSTSDLRIYNLKNISQYDFISNDKDRTNELKDNKLHIVSISDYNFTRKQSGLK
                     EINLKDNEFAINCASEDYRPFYEKYIKSQPQNYITVNGVKLKLNQTSLYTNSYNTNTV
                     PLDLGTIIVPDAVVKDLNPIMTTLNIDYKERSSNLENKFMDSYYKFEEKINNSEAYSI
                     LYKSVIDGEKRALNTSFSFVAIYIGIILLISAGAILALQQLIESTVNKERFKLLSKLG
                     VNKKDMKKAIFIQVSILFAVPLILALINALFISKVFFVIMPFIAETGIITTMLLTLGI
                     VIVVYGIYFISSLLESLNIVNDSKEII"
     gene            18187..18312
                     /locus_tag="PC592_002398"
                     /pseudo
     CDS             18187..18312
                     /locus_tag="PC592_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(19054..19599)
                     /locus_tag="PC592_002399"
     CDS             complement(19054..19599)
                     /locus_tag="PC592_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4056359.1"
                     /translation="MNQGRIIVITGSPGTGKTTTASIVAKESNMDKSVHMHTDDFFHY
                     LSKGAIPPHLPESNEQNLVVIEAFLEAAKRYARGGYDVIVDGIVGPWFLEPWRALVRE
                     DYEVHYIVLRASKEETMKRAVERSKLDRKTNVELVETMWEQFCNLGIYESNVIETTTY
                     SIQEAVFAVKEKISSGAALLS"
     gene            complement(19799..20575)
                     /locus_tag="PC592_002400"
     CDS             complement(19799..20575)
                     /locus_tag="PC592_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(9) family aminoglycoside
                     nucleotidyltransferase"
                     /protein_id="HDF4056360.1"
                     /translation="MNINEFPQQVNQVISIAETILQGQILGIYLYGSATMNGLRPDSD
                     IDILIITKQELSNSIRADLTKQLLKISGSVGCIEKRPLEVTIINQSDIVPLQFPPKCQ
                     YMYGEWLRGEMEAGEYPQACNDPDIMILLWQARKNSITLKGAESKELIPAIPFHEIKK
                     AIRFSLPGLISSFKGDERNVLLTLSRMWFTLVTEEITTKDVAAKWVILKLPERFPPLL
                     TTAKEAYLGNLSDEWETVEKEAMALVEYMKKQIEELLRTE"
     gene            complement(20600..21370)
                     /locus_tag="PC592_002401"
     CDS             complement(20600..21370)
                     /locus_tag="PC592_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HDF4056361.1"
                     /translation="MPLVKHDYPVLEYDTASKAVFQPGNGKKCFPAKAVFAFLGDEVE
                     NYAHTHDGIQIDEFESATRRYPIYECLYNQEKICLCPAPVGSAAAVQVLEYLIAGGVT
                     KIISVGSCGVLEDIPENRFLIPVSALRDEGTSYHYLPPSREVEISKAGINAIESALSQ
                     KNIPYWEVKTWTTDGFYRETVEMVQYRKEEGCQVVEMECSALAACAKFRKVTWAMLLF
                     SADTLADPHKYQEREWGKTSISIALELALDAVLSVVEE"
     gene            complement(21395..22192)
                     /locus_tag="PC592_002402"
     CDS             complement(21395..22192)
                     /locus_tag="PC592_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4056362.1"
                     /translation="MALPGTPGQRISDLCNGNHITQKELAEKIGVSASQLSRIVSGET
                     RTVSSDILIGVAKEFKVSTDYILGLSTVSVRKSYDISELGLSEGAVRGLVTGAVDVQI
                     LNRLLEHRNFPKLIDLIRIYFQDTAAKGITARNQLIEIATASLSDLMKEHPEHRAEAK
                     QDLQLLNAQKMGEHEAEIEKIKNVFLAILRDIKKDIYNGEQPGEAVTAAMFQAMRDAL
                     AEQKQNPLSIDDVAAMVAGQIGQLTPMDEETADLFKQLAKKMMKGIE"
     gene            22531..22944
                     /locus_tag="PC592_002403"
     CDS             22531..22944
                     /locus_tag="PC592_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDF4056363.1"
                     /translation="MRDNPYKDLPPLERRPDGSLYRMTPAQRKQAASLIRRECCCCED
                     GNCIVLDDGDTCTCPQTISFSVCCKWFRWAVLPLDGTLEAEIVRDKDLKRCAVCGGVF
                     VPKSNRAKYCPGCAARVHRRQKTESERKRRSAVDS"
     gene            23056..23451
                     /locus_tag="PC592_002404"
     CDS             23056..23451
                     /locus_tag="PC592_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF4056364.1"
                     /translation="MTNTIYIHQPEKAFSFTRLPNFLFEAPTFKPLSNEAKVLYAFIL
                     RRTELSRKNGWADDCGRIFLYYPICEVVTLLHCGRQKAVNTLRELQYAGLVEIQKQGC
                     GKPNRIFPKSYEAVPNTDFKKSGSGTPED"
     gene            23641..>24417
                     /locus_tag="PC592_002405"
     CDS             23641..>24417
                     /locus_tag="PC592_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDF4056365.1"
                     /translation="MAKHAILRFEKHKGNPARPLEAHHERQKEQYASNPDIDTSRSKY
                     NFHIVKPEGRYYHFIQSRIEQAGCRTRKDSTRFVDTLITASPEFFKGKSPKEIQAFFQ
                     RASDFLIGRVGRENIVSAVVHMDEKTPHLHLTFVPLTKDNRLCAKEIIGNRANLTKWQ
                     DDFHAYMVVKYPDLERGESASKTGRKHIPTRLFKQAVSLSKQARAIEAALDGINPLNA
                     GKKKEEALSMLKKWFPQMENFSGQLKKYKVTINDLLAENEK"
BASE COUNT         9126 a         3278 c         4476 g         7537 t
ORIGIN      
        1 tcaattttca acattctata caattataca taaattatac agcataataa tcatcaaaat
       61 aacaaatttt aaaaattaag caaaactttt tgtcgaagtt caacgtctat atatatgtag
      121 tgtaaatttt tggaataaaa tactacaaaa atataaatgt aaaaatatag taatattgga
      181 ggtcgaacga tgagaaataa aaagaaaaaa ataaatagaa agaagttgta tttgctttta
      241 agtgctattg tagtgtgtct ggcttttgta gtagttggtg cacgcgttag ctctttaaat
      301 atgaaagaaa atgaaattag tagaaatgca aaactgtcaa gttctactat tacagatata
      361 gtatctaata cagcaacaga agttagtaaa gggccaagta aaagttctgg aaaagtagca
      421 tacataacta tagatgatgg tccatctaaa tttactgacc agattataaa aactttaaat
      481 aaatataatg ttaaagcaac tttttttatg atagatggaa atatgaagga atatccacag
      541 caagttaaaa atataattaa aaatgggaat acagcaggtt ttcatagtgt atcacatgat
      601 attcacaagc tttatgttac tagtacatca gcaaaagaag aatttgatac aaatgatcaa
      661 actttttata agataactgg caaacattca aaagtaataa gaatacctta tggaagcaaa
      721 ccatatacac cacaagcttc ttatcaggct ttagttgatg ctggatataa aatttgggac
      781 tgggacttag atacagaaga ctggagatct aattcttctc aaattataca aaatgtaaaa
      841 aatcatatta agaatagaaa aggtgaagat aaagaccaac ttgtagtttt aatgcatgag
      901 aaaaaacaga gtgcagaagc tttagattca gttttaaaat ttttatcaga tgaaggttat
      961 gaatttgctc cagtagatca aaatcaaata ccaaaaaatt attggttacg taatttagag
     1021 tagttaaaat ataagaatat taattgatat ttttagaaat tgagaataaa aatgagtgag
     1081 gtgtaggtat attgaataaa aaactttata taggaatggt cggaatattg tctttgatga
     1141 tggttggttg taataaaagt ctagcaaaag taaatgatgt ggaaattaca aaggaacaat
     1201 acaaaaaaac aaaagcagtc ttatctgcta ctaataatta tataaatggg cagtctttag
     1261 atgaattaga aaaaactttg gataaaaaag gtagaaataa attagaaaat gttataatat
     1321 cgtttatggt ggataatgaa cttttatatc aagaggctaa ggataaagga ctaactccaa
     1381 gtaaaagtga agtagactca aaatatcaag aactagaaga taagatgaat ttgaatacaa
     1441 gctataagga aaaaatggac aaagcaggtg ttgataaaga atatttaaaa caagaaatat
     1501 caagagattt agccatagat aaaaataaaa aagcctttga agatagaata aacataagtg
     1561 ataatgatat ggaagcctac tatacaagtc ataaaaaaga ttttaatgta gaagaaataa
     1621 gtgcttctca gatacttata tcgactttag acaaaaataa aaaagaagta agtaaagata
     1681 aaaaagaagc tttgaagaaa aaggcagata atatattgac taaaatcaaa aatggagaaa
     1741 gttttgaaag tttggctaaa aaatattcag atgataaagc aactggaaaa aatggaggac
     1801 agctaggata tttttcaaag gatgacaaaa atgctgagtt tacaaaggaa gtgttcaaat
     1861 taaagaaaaa tgaagtttca aaggtgtttg aaactagtta tggatatcat atagtcaaag
     1921 ttactgataa aagagaaaga caaaaaagtt ttaatgagtg tcagagttta ataagagaat
     1981 ctattttaaa tgaaaagtat attgagcata taaaaaaatt aaatgaagat gctaaaatag
     2041 acagatagaa tttctaacag ctcaatcctg gcctgtaatc ggagggagat tttacaggaa
     2101 tgtttaagag tttaaagaga acgaaagttg agaaatacat tatcgataat aaagactctt
     2161 tttatagaat agcatatagt tatacgaaga atgaggaaga tgccttagat gtggttcaag
     2221 aagctatgta taaggcacta tactcagtgg aaaatattaa agaagtaaat tatataaaga
     2281 catggtttta taaaatttta attagaacga gtatagattt tattagaaaa aaccgtaaat
     2341 ataataatat gacagatatt gaccttgtag atgagactgg agagtatgat aaatatactg
     2401 atttggattt aagaagagct ttagaagaat tacctattga atacaaatct attataatat
     2461 taagattttt tgaagattta aagattgaag aagtagcaat aatattggat gaaaatgtga
     2521 atactgttaa aactaggtta tatactgctt taaaaaaact aaaattaaaa attgaagagt
     2581 agggataaaa agaatgacaa gcaaagaaag gttaaataag ttaaaagagg agtatcataa
     2641 aattccaata cccaagaaac tagatactat aataaatcat gaaaaaatag aaaatatata
     2701 tcaagagaaa aataaaaaag taaatagatt aagatttaaa gttgcaatag cctttgcatg
     2761 tatatttaca gtattagtaa atataagtcc tgtatttgca gacaattttt ctaaaatacc
     2821 tgtaattgga gcaatagtag aagtgataac tataaaaaat tatagtttaa aaagtgaaaa
     2881 ttatgaagct gagattgata ttcctaaaat acgaggttta aaagataaaa acttagaaca
     2941 aagattaaat agtagtttta tggaagatgg aaaaagactt tatcatcaat ttgaagagag
     3001 aatggagaaa atacaatcat caaagaataa gggacataaa tctttaagtt tgagttatag
     3061 tgtaaaaaat aattctaaaa aatttctatc aatagagatg acaaaaaatg agatagaggc
     3121 ttcatcatat gtgagtaagg tacattatac tattgataaa aaaagacaaa tagtcttgac
     3181 tttgccaatg ctttttaaag atgataagta tataaaagtt atcagtgata atataaaaga
     3241 acaaatgaga gaacaaatga aaagggatag tacaaaattc tattttatag atcaaaaaaa
     3301 agaattacct gttgaagatt ttaaaacaat taataaatat caggattttt attttaataa
     3361 aaatgaagaa cttgtaattt gttttgacga atatgaagta gcacctggtt atatgggtgc
     3421 agttgagttt gtaataccat ataaagtaat aaaagatttg taaattaata gtagtttata
     3481 tataaatatt ttaaggagtg caatataact acatataaaa aacttaaaaa atctatattt
     3541 aaaattgcta tagtttcaat atgtttatta gtatcattag taattacaaa ccctatattt
     3601 tcagataatt tttctaatga gacttaaact agtgatatga taaaggtgtt acatgctaag
     3661 agtttcaact ttaaacaaga caattatgaa gtgaaggtta gtattcctaa aataaaaggt
     3721 ttaaaagata aaaatttaga gattaaatta aataatgaat ttttataata tgggataaaa
     3781 atttacagtg aacttcaaaa taaaataaaa aaataataag gggtatagat acctaaatgt
     3841 aagctataat gtcaagaata attctgagga ctttttatca atagaaatga caaaagaata
     3901 gatagaagcc tcctcatctg taactaagaa gcattacact atcaataaaa atagagaaat
     3961 actattaatt taccaatatt ttttaaagat agtagatata ttagagttat aagtgataat
     4021 ataaaagaac agatgagaaa ttacattaag aaagataata caaaatctta ttttatagac
     4081 caagataaag gttccctagt gaaagagttt gaatgtataa ataagtgtca agatttttat
     4141 tttaatagaa atggaaatct tgtaattagt tttggtaaat atgaattagc gcctggttat
     4201 atgagagcag tagaatttgt gataccaaat gaagtaataa aaagcctaag atagatatat
     4261 agaagatttt tagatagact ggtaaggaga attatatgaa tatatatgaa caagcaataa
     4321 gattaataga aaataatgag gattttgcat ttgctacaat aacttctcat tcaggttcaa
     4381 caccacgtga aactggagca atgatgattg taaaaaatga ttctactata tttggttcag
     4441 tgggaggagg tagtgtagaa gcagaatgta taaaacatgc aattaatgtt ataaaaaata
     4501 gagaatcgat gctgtataaa tttactctaa acaaatctga tgtggcaaaa ctaggaatga
     4561 tatgtggggg tactggagaa atacaaatag attttataga tagtaaatta aaaagtaata
     4621 tagaaaaatt caataagaga ctaaaggaaa atacgagtaa agcgtatata tttggagcag
     4681 gtcatatttc aagagatgtt gctgtgatac tatctctttt agaatttaga acagtagtaa
     4741 tagatgatag agaagaattt gctaatcatg aaaggttccc agaatcagaa gtaatagttt
     4801 tagattcttt tgaagagata ccagattttc caactgatga aaatagctat ataattattt
     4861 taacaagagg tcatttatat gattcaagtg ctttagaatg ggctcttaaa agagatgctg
     4921 gttatatagg tatgattgga agtagaacaa aaattggatt gacgtacgaa aaactcatga
     4981 aaaaaggttt taagaaggaa gaattatcaa gagtacatgc accaataggc ataaaattga
     5041 atgctcaaac accagctgaa atagctgtat gtatagctgc tgagcttata aactgtagag
     5101 ctaataagga aaaataaact aatgaacata ggaagcaaag atagtgatat tttaaatgtt
     5161 aattttagag ggattgatat aaaagtaatt ttagtatata aaaatagaaa aaatatttct
     5221 ataaaaatag atccatttgg aaaagtaatt gtgatgagcc ctcctaaaat gtctaaaaaa
     5281 ataataaaag atataatcat tgaaaaagga gactggatac ttaaaaagtc agaaaagtat
     5341 aaaggaagag aagaagtata cgaacaaaga atgtttataa ctggcgaaaa atttctttat
     5401 ttaggtgaag agtaccatct agttataaaa gaaatgttga aagattctgt taaaaaaagt
     5461 aactgtaaaa taactattaa cgaatatgaa ataatcgttc agacaaatga tacaagtact
     5521 gattttatta aaaaatcttt aaagtcttgg tataagatag aaagtgaaag attagtgtta
     5581 gagagaatag attttcttaa attaaattat gaaataatga atcaattagt tccagcaagt
     5641 gttaaggtaa aagaacaaaa aaagagatgg ggaagttgca catctcaaaa aaatatttat
     5701 ataaactcaa aaatatctat ggcaaaatta gatgtaattg attatgtaat aatacatgag
     5761 tttagccatt tagtacatat gaatcactct aaaaaattct atgatttagt aaaatctatt
     5821 atgccagatt ataaagacaa agaaaattgg ttaaaaataa atggatataa aataacaatc
     5881 tgaaaacggt tattccaaaa cataggtgta aaatgtaaga gaagtattat tgtgaaaaaa
     5941 ataaataatc tgaaaatttt aaaaaaagtc gttgacattg taaatgatag ggaatataat
     6001 ctatattaac aacaaaacag aactgaaata taaaattaaa aaattaaaag caatgacaga
     6061 gacaacaata ctaatagtgt tatccacaga gaaccaatgt tgctgagaat tggtgttaac
     6121 ggtagtataa tgatcactct ggagcttttg tactgaatat ttttagtaag tacaaacgtc
     6181 tgtcaacgtt acatgactaa ggttaaggta attaattatc cgacctgaaa aaagaggggt
     6241 agatgtattt ttatatctac aaataaggtg gtaccgcgga ataaaacttt cgtccttata
     6301 agtaatattt atattgctta taaagatgaa agttttttta ttttaagtga tataaataaa
     6361 tttaatccat ataaaattaa taaaaaaata ataaaaacaa ggaggaattt ttatggaaaa
     6421 tactgtatat gctaaattaa accaaggaat agattctttt ttaagagtgg ctatgactct
     6481 aagaagaaga gaagttgata tacaatcaat aagcatgact gtagataata tgaataactc
     6541 aggtataaaa ttaatagtaa atgaagaaaa gacatcttta gattctgtct taaaccacat
     6601 gaaaaaacta catgatataa gagagataac tgttgaaaga atgaaacatt aattaaatat
     6661 atttttataa agctaaagat aaatatgctt attttaaaat aaaaaactaa agataaatat
     6721 taaataagaa aaatcttaga ttaaagtaca agtatcattg aatttgtcag tttatcatat
     6781 ctgataaaaa ctgaaaattc taaaaatata attgtaaaac tatataaatt tagaatttaa
     6841 atctgttgaa taatattaaa ataatgataa tgagtatgaa tttctaataa aaataaatat
     6901 cataaaaata agaaaaagta ttgggaggaa atgaaaatgg caagaatgta ttatgaaaaa
     6961 gatgtggatt tagaggtttt aaaaaataaa aaggttgcag ttttaggtta tggaagccaa
     7021 ggacatgcac atgcacaaaa tcttagagat aatggtgtat atgtagtgat aggtctttat
     7081 gacggaagta aatcagcaca aaaagcaaaa gaagatggat ttgaagttaa gagtgtagca
     7141 gaagctacaa aagaaagtga tttgataatg atgttaatgc ctgatgaaaa acaaaagaaa
     7201 gtttatgaag agagtgtaaa ggataactta aaagaaggtc agacattagc ttttgctcat
     7261 ggattcaata tacattataa ccaagtacaa ccaccagaat ttgttgatgt tgtaatggta
     7321 gctcctaaag gacctggtca cttagttaga aatgtattta caaagggaag tggagttcct
     7381 gcactatttg cagtatatca agactacact aaaaaagcta cagagacagt tttagcatat
     7441 gcaaagggga taggagcaac aagagcaggt gttttagaaa ctacttttaa agaagaaaca
     7501 gaaacagatt tatttggaga acaatcagta ctttgtggtg gaataagtga acttataaaa
     7561 ttgggatata aaacgcttgt agatgcaggt tatcaaaaag aagtagcata ctttgaatgt
     7621 ttacatgaaa tgaaactaat agtcgacctt atatatgaag gtggatttga aagaatgaga
     7681 tatagcataa gtgacacagc agaatatgga gattatgtat ctggtaaaag ggtaataact
     7741 gatgccgcaa aacaaggtat gcaaaatgtt ttagaggata tacaaaatgg aaaatttgca
     7801 aaagcgtgga ttaaagagaa tgaagaagga cgtgagaact tcctaaaaac tagagaagaa
     7861 gaatataata cagaaattgc cgaagttggt agaaatctaa gaagtatgat gtcattctta
     7921 aaataaatat atattaaatg gattagtttg agggaaagag tggtgtatag tagtgcgtat
     7981 gaatggagca aaggtaattt tagaatgttt aaagaaagag ggcattgaca caatatttgg
     8041 atatcctggt ggagcagtaa tacctcttta tgatgctcta tacgattatt cagatgattt
     8101 taaacatata aggacatctc atgaacaagg tttagttcat gccgcagatg ggtacgcaag
     8161 aagtactaat acagtaggag tttgttttac aacgtctggt ccaggagcaa caaatgccat
     8221 aactggaata gcaacagctt ttatggattc ttcacctatg gttgtaatct caggtcaggt
     8281 tccaacaagc ttattaggta aagattcttt tcaagaaatt gacataactg gagcaacatt
     8341 atctatgaca aaacataatt atttagttag aaacactaaa gaattagttc ctacaataaa
     8401 agaagctttt aaagttgcaa attcaggtag aaaaggacct gtacttgtag atgttccaaa
     8461 ggatttattt ttagcagaaa tggattttag tgatgaagat tatgatttat gtcaaataga
     8521 tgattatata gattataaga gtgattttag tttagatgat gaaattaatg tcaagctttt
     8581 aaatgaagca atagatatca taaaagaatc taaaaagcct gtaatatatg ctggtggagg
     8641 agttaagtct tcagatagcg aggatattct tgaaaaattt gcaactaaga tagatacacc
     8701 tgtactaaat acacttatgg gtcttggtaa tatagataga aaaaatgaac tatctcttgg
     8761 aatggttgga atgcatggaa gtagagaaag taatttagcc ctttctaatt cagatttagt
     8821 gatagcgata ggtgctagat ttagtgatag agtaataagt aaaagctctg aatttgctaa
     8881 aaatgcaaaa ataatacaca tagatataga cccatctgaa ataagtaaaa atatagaatc
     8941 taatgtatct ttgattggag atgtaaagtt agtccttagc ttactaattg aaagggtcga
     9001 aagtaagaat aatagcaatt ggaaagaaga gataaagaca tttagaaaga gtgagggtat
     9061 acaaacggat gaatttcatc cacaaagtat acttaaaaaa ataaatgaga aatatgaaac
     9121 attaaagaag cctactgtgg tagtaactga tgttggtcaa catcaaatgt gggctgctaa
     9181 atactggaat tttaaaggaa ataaaagttt tataacatca gcaggattag gaactatggg
     9241 atttggttta ggtgcagcta ttggagctaa agttggtaat attgataaaa atgtggtttt
     9301 agtaactggt gatggaagtt ttagaatgaa ctgtaatgaa ctagctacag ttgcaaatta
     9361 taatgtacct atgcttattt tactactcaa taatagaacc ttaggaatgg taagacaatg
     9421 gcagaagtta ttttccaatg aaagatactc tcaaactgat attaatgaaa atgtggatta
     9481 tgttaaactc gtaaatgcat ataagattga tggatataag atatccaata tggaagaatt
     9541 aggaaaggta ctagatgtga tagattttaa taaacctgtg tttttacaat gtgatataga
     9601 taaggattat gatgtttatc ctattgtagc acctaatgat gcattagaaa atttgatatg
     9661 taactaaaac ttatactgaa tattgataaa attttttatt aaacttttat tgatattcag
     9721 tttttattta gagatagagt ggtatttttt atttttgtag ataaaaaaat gaatatataa
     9781 ttaagaattt atcaaatttt aattatacaa tttagaataa tattacaact taagtaaata
     9841 ataattttga ataataattt acggaggtat tcatatgttt aaacacgata aagcattatt
     9901 aaaagaagta aaagtagaaa gaccaaatcc tcaatatgct gttttaatgc aagaacagtt
     9961 gggtggtgca aatggagagt taaaagcagc aatgcaatac ttgtcacaaa gttttagaat
    10021 aaaagaccct caaataaaag atttatttct tgatatagca gcagaagagc ttagccatat
    10081 ggaaatggta gcacaaacta taaatttatt aaatggacat gatgttgatt ataatgcagt
    10141 taatacaggc gaaatagaaa cacatgtatt aactggtttg tcaccagttt taataaactc
    10201 atcaggagct ccttggactg ctaattatgt tacagttaca ggggatttag tagctgactt
    10261 attatcaaat atagcttctg aacaaagagc taaggttgtt tatgagtact tgtatagaca
    10321 aatagatgat aaatatgtaa aagaaacaat agatttctta cttaatagag aagaagcaca
    10381 taatgctcta tttagagatg ctttaaataa agttaaagat acaggttcaa atagagattt
    10441 tggagttaca gaagattcta agttatattt cgatttatct actccagggc caaatcatga
    10501 tactaagata gatgttaatc ctccttcttt tgaaaaacct ttaaaaaaat aattttatat
    10561 tttttatgtt attttagtag tcataagaaa ttatttacta gaagagttta ttagataaaa
    10621 aattaaatat gtatagttaa aaatgggtat acacttacta taagtgtata tctatttgtt
    10681 tattgcaaaa catataataa aataacaaat gaggtggtat tttggacagt aatagaaaac
    10741 ctaataatct aataaatgaa aaatctccat atcttttaca gcatgcatat aatcctataa
    10801 actggtatag ttggaatgaa gaggctttta aaaaagcaaa agaagaggat aaaccaatat
    10861 ttttaagtgt aggatattca acatgtcatt ggtgtcatgt tatggaaaaa gaatcttttg
    10921 aagatgaaga agttgctgaa ataatgaata gaaattttgt tgcaataaaa gtagataaag
    10981 aggaaagacc tgatgtagat agtgtgtata tgacagtttg ccaagctatg acaggtagtg
    11041 gtggatggcc aatgactata ataatgacgc cagataaaaa accttttttt gcaggaacat
    11101 acttcccaaa atattcaagg tataatagac ctggagttat agatttatta gagaatgtat
    11161 ctgaaaaatg gaatacaagt agagatatac taataaaatc tggagatgaa ataatagaag
    11221 ctcttaagga tgattttggt gtaaaaaata ctgaaggtga tttatcaaaa gagatgttaa
    11281 gttcatcagt tagagtattt aaggctattt atgatgaaaa gtatggtggt tttggtaatg
    11341 cccctaaatt tccaagtcct cagaatctta tgtttttgat gaaatactat agtatagaaa
    11401 aagataaaga tgtattaaaa atggtagaaa aaactttaga tggtatgtat agaggaggat
    11461 tgtttgatca tattggattt gggttttcaa gatactctac tgataaaaag tggttggctc
    11521 ctcattttga aaaaatgcta tatgataatg ctatgcttac tatagctttt ctagatgcgt
    11581 ataaaataac aaataaagag ttatataaag aaattgctat gaaaactata gattatgtgg
    11641 ttagagagat gcaggataaa gatggtgggt tttattcagc gcaggatgct gatagtgaag
    11701 gtgaagaagg taaattttat acatttaatc ctcttgagat aattgaagtg ttgggtgaag
    11761 aagatggaac tttctttaat aattattttg atataactag tagtggaaac tttgagggca
    11821 aaagtattcc taatcttata aaaaataaag aatatgagag acataatgaa aagatagata
    11881 accttagtaa aaaggtattt gaatatagaa aagaaagaac atctttgcat aaagatgaca
    11941 agatacttac atcatggaat gcattgatgg tagttgcttt aacaaaggca tatagtactt
    12001 taaaaaatga tatgtattta gattattcaa ataagtgcct tgattttata aataataatc
    12061 ttgtaaatga gtcaggtaga ttgttagcta gatatagaga tggaagttcc gactatttag
    12121 catatttaga tgattatgct tttttaatct gggcgtatat agagctttat gagtcaacat
    12181 ttaatatgaa atatttggaa aaggctttaa atttaaatga aagctgtatc gatctttttt
    12241 gggattatga aaaaagtgga ttttatatat atggtaaaga tagtgaaaat ttaatagcaa
    12301 gaccaaaaga tttgtatgat ggagctattc catcaggaaa ctctgttcaa ttatacaatc
    12361 ttataagact tgcgaaaatt actggcgata ataaacttga agaaatgtca tataaacaat
    12421 taaaactgta tgtgaataat gtaaagagtt ctccaactgg ctacagcttt tatatgcttt
    12481 cattgatgtt tgaactttat tctactaagg aaattatatg tatttttaag gaagattccg
    12541 atttaagtgc atttaaagaa ttgataagtg aaaattttat accaaataca acttttttag
    12601 caaagaaata caatgaagaa aatactatta taggtttttt aaataactat aaattaaagg
    12661 aagataagac tagttattat gtgtgtcaaa gtaatagttg tagccaacca attaataatt
    12721 tacaaaaatt aaaagatatg attttaggag tagaataacc agaatagtga aaaaggagat
    12781 gtcttaaagt aaaaatctaa tcatctcctt tttttgtaca aaaaacaaaa aatagtttct
    12841 aagaacactt aatctatgta ataattgttt tgttaaaaga tgaaaatgat attatagtta
    12901 tataaaatat tgcattataa aaaagtggta ttattataga tgttatagta ttaatcgttt
    12961 ttatttacct atttcttatt tttacaaatt cttcaagtgc ttcagattta attttattta
    13021 tttcttcata ttcccaaaat tagcaccttc tttaaagccg tcttgttctt cattattaaa
    13081 acaatacatt ttttagtaaa ttccacaagg tttccaattc atctttgata aattcatgaa
    13141 atacatctgc cattaagttt attacagctc taccacatgt taccataact tcttttccta
    13201 agtctataac tttaacagta attgctctct tatcatgagg acttgtaatt acatcaatat
    13261 atccattttt tttaagatta acaactatcc tatttatatt ttgtttactt gtgaccattt
    13321 ttcttgcaat attatttaat gttgtttctt cttctgataa atgaagagta gataaaatag
    13381 tcatatactg tcttgaagta agtataccaa aatatttata tccttctatt tgtattttgt
    13441 ttgtaatggt aaaaaagttg catatgtttg attcattaaa aagagttctt ttagttaatt
    13501 tgaataatct attaaatatc tactttatct ttagatgttg ttttgtcgaa aataaaatat
    13561 catgaattaa ttctaatgtc aatatggtat caaaatatat taaagtatta cttttttatg
    13621 caaatattaa ttaaattatt atataatttt atgtaataat ttctatacac aatgataact
    13681 tctatgaagc attaataatt cttaaatttt tttagaaaga ttttgacttg aaaacacttg
    13741 taatataata tataaattaa tatactgaat aaaatcaatc tggagggata attatgaagt
    13801 gtacaaactt tactttcaaa ggagaggaag gtttagatat atatacatat aaatgggaag
    13861 atgaaaatat aaaaaatcca aaggctgttg tccaaattgc gcatggaatg gctgaaactg
    13921 cacaaaggta tgagactttt gccaaggtgc ttactaaaaa tggttatata gtatatatca
    13981 atgaccatag aggtcatgga aaaactgcaa agataataga aaatgttggg catttagctg
    14041 agaaagaagg ttttagatgt cttgtagagg acatgtatac tttaacaaat attataaaga
    14101 aagaaaatga agatttgcca atttatctat ttggtcatag catgggttca tttgcaagtc
    14161 aaagatatat aatggattat agcaataatt tatctggtct tatactatgt ggttcaaatg
    14221 gaaggcaagg aatcattcta aatcttgctc atatgataat caatcgtgag attaaaaagt
    14281 atggaagacg ttctagaagt aataaaataa atgatttgat ttttggtggc gaaataataa
    14341 gaagaaatga gaagactaag tttgattggt taagtagaga taaagaacaa gttgagaaat
    14401 atatcaatga cccattttgt ggagtggtgt gtagttgtgg ctttttttat gatttaattc
    14461 aagggttaaa agaaattgag gataaagaaa acttaaaaaa agtgccactt gatgtaccta
    14521 tttacataat atctggagat aaagacccta tagggaaaaa tagtaagggc gtcttaagac
    14581 taagggatag atatataaag ttaggagtaa aagatgtaac ttgcaaactt tacaaaggtg
    14641 gaagacatga attattaaat gagataaata aagaagaagt ttttgaggat gtaatttgtt
    14701 ggctaaacaa taaaatagga atattgtgat aaaggaatat tatattaata ttaaatttaa
    14761 ttctatgtaa atgtttgaaa agtatattta atatgtgtaa aacagaaaag aaagtgtttc
    14821 aagatgatta tttattatca atgaaacacc tttttatttt ttgataaata tatttaccac
    14881 tttcaagaga agagtgtttc aaaatcttaa gaaaatcttt tgatttaagt atatgttttc
    14941 ttaagaaaat taaattattc tattaaaaga actagaaata agtaagtgat tttggttttg
    15001 ataaatataa gaatctttat ttattaagtg cgtaaaaaat ataaatttat ttggttttaa
    15061 ttccaaagta aaacttaatg gaggtaatag atatgagcaa aatattaaga gtaaaaaata
    15121 taaaaaaata ctataaaagt agaggtaaca ttacaaaagc tattgataat attagctttg
    15181 aagttgaaag tggagagtat ataggtatta tgggagcttc aggaagtgga aaaactactt
    15241 tactgaattg tatttctact atagataaaa cgacagatgg gaatatatat ataggaaata
    15301 aagatataac aactatgaat gaagatgagt tatctaaatt tcgtagagaa gaactaggtt
    15361 ttatatttca agattttaat ttattggaca cacttacagc acatgataat atagcattgt
    15421 ctttatctat caatggagtc aattcaaaag aaatagataa taaaataaaa aaaatagcaa
    15481 ataaattagg tgtttatgaa atacttaata agtatccata tgaaatgtct ggtggtcaaa
    15541 agcaaagaat agcatgtgca agagctataa taacaaatcc atcactaata ctagcagatg
    15601 aacctacagg agctctagac tctaagtcag caaagttatt tttggaaaac cttgaagttt
    15661 taaatcgtga attaaaagct accatattaa tggttacaca tgatgctttt acagctagtt
    15721 attgtaaaag aatattattt ataaaagatg gtaaaatatt caatgagttg gttagaggga
    15781 ataatactcg tcaagaattt tttgatagaa taataaaagt aatatcagtt cttgggggtg
    15841 atgataaaca tgttttttaa aaaaaataaa tcaagaaggt ctagaaataa aagaaaaaat
    15901 aattatgttt caagagtgtc aagtgaatca tttaaaaaat tagctttaaa taatgtgaaa
    15961 aagagtctaa aaaattattt gatttatttt ataacccttg tatttggtgt tattatttta
    16021 tacactttta attctttaga caatgatata gcaattctta gtagtaatgc tttattgagt
    16081 tcaagtatat cgtttgttag gggtattgta agtatttttt caattctagt ttgtattata
    16141 tttgcatttt tgattattta tgcaaataac tatttaatga aacaacgtaa aaaagagttt
    16201 ggaatataca gtattcttgg aatggataga agagatataa ataaattaat gtttagagaa
    16261 atgatgataa taggcatatt ttcattaata ataggtatta tatttggagt atttgtttct
    16321 aagggactta gtatatttgc cttaaagatg ttgggcatat catcatcagg attttctttc
    16381 tcaatgctta caactattaa aacaatagta ttttttggca ttgtactgtt attagtcaat
    16441 aaattcaata aaaaaacaat aaaaaaatac aagttaatag acttattaaa tgcaaataaa
    16501 aagaatgaag tttcagttgc aaaaggaaaa aaatctaatt tgatattatt ctttttatct
    16561 atagtggcaa ttgttttagc atatataata ccattgaaaa tgaaaatatc tacatttata
    16621 ttaggtatat gtttaatttt aatattagtt ggaatttatt tgttttttat gtcagtatct
    16681 gattttataa tgttaaaaat aaagaagcat agatttatat actataaaaa tttaaatcca
    16741 tttatagtaa gccaaataag tagtcaaatc aaaacaatga gtatgtctat tactatgatt
    16801 tgtatgttat tattttcttc tttgatagta ataccatttg gtatatcatt tggaaaatat
    16861 ttaatagatg atttacaaga agcgacgcct tatgatgtaa cattatctaa attgtatatg
    16921 aatggagata acattgtaga atacagtaca aagaaaaatg atatagatag taaaactcct
    16981 tcacttaaag atgaactaat agaaaatggt tttccactaa cttcattttc taaaagtaca
    17041 agtgatttaa ggatatataa tttaaagaac ataagtcagt acgattttat atcaaatgat
    17101 aaggatagga caaatgaact gaaagataat aaacttcata ttgtctcaat tagtgattat
    17161 aattttacta gaaagcaaag tggtttaaaa gaaataaatc taaaggataa tgagtttgca
    17221 ataaattgtg cctcagaaga ttatagacca ttttatgaaa agtacattaa gagtcagcca
    17281 cagaattata taacagtaaa tggagtaaaa cttaaattaa atcagacaag cttatatacc
    17341 aattcttata atactaatac agttccttta gatttgggaa ctataattgt tccagatgct
    17401 gtagtaaagg atttaaatcc tattatgact acattaaata ttgattacaa agaaagaagt
    17461 agtaatcttg aaaataaatt tatggattca tactataaat ttgaagagaa aatcaataat
    17521 tctgaagctt atagtatttt atataaatca gttatagatg gcgaaaaaag agccttaaac
    17581 acttcatttt cttttgtagc aatatatata ggtattatat tattaatatc agcaggtgca
    17641 atattagcat tacaacaact catagaatca actgttaata aagaaagatt taaattatta
    17701 agtaagcttg gagtaaataa gaaagatatg aaaaaagcta tttttataca ggtatcaata
    17761 ttatttgcag tacctttaat attggctctt ataaatgctc tgtttatatc aaaagtattc
    17821 ttcgttataa tgccatttat tgcagagaca ggtattatta caactatgtt attaacatta
    17881 ggtattgtta tcgttgtata tggaatttat tttatttcaa gtttacttga aagtctaaat
    17941 atagtaaatg atagtaaaga gataatctaa gtctttaaaa agactattta ttgtgaatct
    18001 attaattaag ttacacttaa gttagcttag ttaatagatt ttatatttta attcaatgaa
    18061 agaatctttt agactaaaat ataaccaata gttaaattat gaatatttta ttaactttga
    18121 ctcaatttac ttgtaagtac tttttttata tacttaaatt acaatagtta tgctagggag
    18181 gtatatatgc aaattaaaat aggtaaaatc atacaagctc ttagaaaaga aagaaatcta
    18241 actcaagagc aattggcaaa atttatagga gtatcaacac cagcagtatc caaatgggag
    18301 agtggggtat cacttagata aagataccac accattccca cgctgacttt tgctcaaccg
    18361 atacagccgg agggctggat aacaagaaaa ggcggtatgc gccccgtgga ggggtagcgt
    18421 accgcctttt cttgtggggg tttccaaagg gggcaacgcc cccatttggc acacgacttt
    18481 gcgaagcaaa gtgtagtgtg ttatacgctc tgtcggcgtt gccgtgaaaa tgccgttgcc
    18541 gccggggagg gcaagggcat ttgaagcggc aggaaaacag ggctgtgctt gcgtggcgta
    18601 gagccgtaag cacaggtctg gtttcaacag cagactgggc gtatatgaaa gcccccgtcc
    18661 ctcgtcctac gctccgactt gtggacaaag tgtcccgaag ttgtggctac actcccggaa
    18721 aagtaacagg acagcgggca accgtcaagg ctgaaatgaa cgggtttaca ctcggccttg
    18781 accgccaccc gccgtcccgc tgaatgggtg gacaaggcgg ccaatccctc aaagtgcttg
    18841 gccgctctcg ttctgatttt ggagcgtttc ttttctcata atgaaatggg cgggaagcca
    18901 ttttagggct ttccctcctt gattgcccat ctgcaaagac gggcgggact gtcaacggcg
    18961 gcgcatgaaa tgcgccgttc attttgaccg ttgactggct tggctgcctt tgctatttct
    19021 ctgataaatg aaatttcgat ttttagaaat cgtttaagat agcaatgcgg ctccacttga
    19081 aattttttct tttactgcaa aaacagcctc ttggatagaa taggttgtcg tttctataac
    19141 attcgattca tatatcccca aattacaaaa ttgctcccac attgtttcta ctaattcaac
    19201 atttgttttt ctgtctaatt ttgagcgttc cacagctcgt ttcatagttt cttctttact
    19261 ggctcttaaa acaatatagt gtacttcata atcttctcga acaagggctc tccatggttc
    19321 taaaaaccac ggcccgacaa ttccatctac aattacatca tatccgccgc gggcatagcg
    19381 ctttgcagct tctaaaaagg cttcaatgac aactaaattt tgttcgttgg actctggtaa
    19441 atgcggcggt attgctcctt tgcttaaata atgaaaaaag tcgtctgtgt gcatatgcac
    19501 agatttatcc atgttcgatt cttttgcgac aatcgacgca gttgttgtct ttcctgttcc
    19561 cggcgaacct gtaatcacaa taattcttcc ttgattcatc tacattctcc ctcgcaattc
    19621 agatttaccg ctctctttct ggttttggag cgtttcttct ctcaagattg aaatgggcgg
    19681 gaagccattt tagggctttc ccgccttgat tgcccatcag caaagacggg cgggactgtc
    19741 aacggcggcg catttatgcg ccgttcatct tgaccgttga ttggccccgc taactttgct
    19801 actctgttct aagtaattcc tcaatttgtt ttttcatata ttctacaagt gccatcgctt
    19861 ccttttctac tgtctcccat tcatcagaca aatttcccaa ataagcttcc tttgccgttg
    19921 ttagcagggg ggggaatctc tccggcaatt ttaaaattac ccattttgcg gcaacatctt
    19981 ttgtcgtgat ttcttctgtt actaaagtaa accacattcg tgataaggtt aataacacat
    20041 ttctttcatc acccttaaag ctggaaatca aaccaggtaa agaaaaccga attgcttttt
    20101 taatttcgtg aaatgggata gcgggaataa gctctttgct ttccgccccc ttcaaagtta
    20161 tgctattttt tcttgcttgc cataataaaa tcattatatc tgggtcattg caggcttgcg
    20221 gatattctcc tgcttccatc tctcccctta gccattcacc atacatatac tgacattttg
    20281 gcggaaattg caacggaaca atatcagatt gattgataat agttacctct aaaggtcttt
    20341 tttcaataca gcctacggag ccagaaattt tcaataattg ctttgttaga tctgctctga
    20401 ttgaattact caattcttgt ttagtaatta tcagtatatc tatatcacta tctggacgca
    20461 gcccattcat tgttgctgaa ccatataaat atatccccaa tatttgacct tgtaatatgg
    20521 tttctgctat tgaaataact tgatttactt gttgtggaaa ttcatttata ttcattgtaa
    20581 ctcctatatg tatttatttt tactcctcaa caactgataa aacagcgtct aaggctaatt
    20641 ctaaggctat ggatatactt gtttttcccc attctctttc ttggtattta tgagggtctg
    20701 caagagtatc ggctgaaaaa agcagcatag cccatgtaac ttttctaaat tttgcacacg
    20761 ccgccaatgc ggaacattcc atttctacta cttgacatcc ctcttctttc cgatactgaa
    20821 ccatttctac tgtttctcga taaaaaccgt ctgttgtcca tgttttaact tcccaatatg
    20881 gtatattctt ttggcttaaa gcagattcaa tcgcatttat accagccttt gaaatctcta
    20941 cttctcggga gggaggaaga taatggtaag atgttccctc atctctcaat gcagaaacag
    21001 gtatcaaaaa tctattttcc gggatgtctt ccaatacgcc gcaggagccg acggaaataa
    21061 tctttgttac accccctgca attaaatatt ctaaaacttg gacggcagca gcacttccca
    21121 caggagccgg acatagacat attttctcct gattataaag acattcataa ataggatatc
    21181 gtcttgttgc actttcaaat tcatctatct gtattccatc atgggtatgt gcataatttt
    21241 caacctcgtc tcctaaaaaa gcaaacactg cttttgcagg aaaacatttt ttcccatttc
    21301 ccggctgaaa aacagctttt gatgcggtat cgtactctaa aacagggtag tcatgcttta
    21361 ctaatggcat attattatct cgaataacag gctattattc tattcctttc atcatctttt
    21421 ttgccaactg cttgaacagg tcggcagttt cttcatccat cggcgtaagc tgtccgatct
    21481 gtccggcaac catcgccgct acatcgtcaa tggaaagcgg gttttgcttc tgttccgcca
    21541 atgcgtcccg catggcttgg aacatcgcgg cggtcacagc ttctcccggc tgttccccgt
    21601 tgtaaatgtc tttcttaata tcccgcagga tagcaaggaa cacatttttg attttctcaa
    21661 tctccgcctc atgttccccc atcttctggg cgttcaaaag ctgtaaatcc tgctttgctt
    21721 ccgcccggtg ttccgggtgt tctttcatca ggtcggacag ggaagccgtt gctatctcga
    21781 taagctggtt tcttgctgtt atgccttttg ccgctgtgtc ctgaaaataa atccgtatca
    21841 aatctatcag cttaggaaaa ttcctgtgtt ccaacaggcg gttgaggatt tgcacatcaa
    21901 cagcacccgt cacaagcccc ctcacggctc cctcggacaa gcctaattca gaaatatcgt
    21961 agcttttacg aacgctcacg gtagacaagc ccagtatgta gtctgtcgat accttaaatt
    22021 cctttgccac acctatgaga atatcactgc tgaccgttct tgtttcgccg ctgacaatgc
    22081 ggctcaactg ggaagcggaa acgcctatct tctccgcaag ttccttttgt gtgatgtggt
    22141 tcccgttgca taaatcggaa atccgctgtc cgggcgttcc gggtaaagcc atagatacgc
    22201 acctcctccg catacttcca ttatacagaa tgattgcaaa aatgcaagtt ccaaagtgta
    22261 aacttcatca aaatgcaatt ctcgcaatat tccgggaatt gcattttttt cgtgtagact
    22321 tagggtagtt catcgatgga cggcaccttg aaaacagaat gaccgtccga aaaggaatac
    22381 cccggctggg gaagcaccgc aaggagtcgg acttcgggac aaaatgtccc gaagttgcga
    22441 ggagcgtgcc aacgccggaa cacgccgcag gaatggggca ggaaaccttt tcggggagaa
    22501 cggcaacgga aagcaaaatg gagggaacgc atgagagata acccctataa agacttgccg
    22561 ccgctggaac gcaggccgga cggttccctt taccgcatga ccccggcgca gagaaaacag
    22621 gcggccagcc tgatacgccg ggagtgctgt tgctgtgagg acggcaactg cattgtcctt
    22681 gacgatgggg acacctgcac ctgtccgcag acgatttctt tctcggtctg ctgtaagtgg
    22741 ttccgctggg cggtcttgcc gctggacggg acgctggaag cggaaattgt ccgggataag
    22801 gacttgaaac gctgtgcggt ctgcggtggc gtgttcgtcc ccaaatccaa ccgggcaaaa
    22861 tactgccccg gctgtgccgc cagagttcac aggcggcaga aaacagaaag tgaacggaaa
    22921 aggaggtctg ctgtggacag ttaggagcga aaaaagcctt gatttatcag gctttgcaag
    22981 ccccaaaccg gggcaggtgg tataaagtat cgcccgcccc ggaaaacggg cttctaaccg
    23041 tccacaaaac gaactatgac aaataccatc tatatccatc agccggaaaa ggcgttcagc
    23101 ttcacccggc tcccgaattt cctctttgaa gcccccacat tcaagcccct gtctaacgag
    23161 gcaaaggttc tgtacgcctt tatcctgcgc cggacagagt tatcccgcaa gaatgggtgg
    23221 gcggatgact gcggacggat tttcctgtat taccctatct gtgaagtggt cacactgctc
    23281 cattgtgggc ggcagaaagc ggtgaatacc ctgcgggaac tgcaatacgc cggactggtg
    23341 gagatccaga agcagggctg tggaaaaccc aaccgcattt tcccaaaatc ctatgaagcg
    23401 gttccaaaca ccgacttcaa gaaatccggt tctggtacgc cggaggactg aaaaccgtac
    23461 ccatgaagta cggaaatcac tcctgagacg tacgaaaacc ggacggtata tagaaatacg
    23521 aaatacaaag ataaaaagat tgatttatat tctatccatt ccaatcctat ccgagctatt
    23581 ttctgcggga ttttccctgt ggaaaacccc ggataggaaa ggaatgggga aaggagcaga
    23641 atggcaaaac acgcaatttt acggtttgag aagcacaagg gcaacccggc aaggccgctg
    23701 gaagcccatc acgaaagaca gaaagaacag tatgccagca atcccgacat tgacacaagc
    23761 cggagcaaat acaacttcca tatcgtcaag ccggagggac gctattacca cttcattcag
    23821 agccggattg agcaggccgg gtgccgaacc cgcaaggaca gcacacggtt tgtcgatacg
    23881 ctgataaccg ccagcccgga gttttttaag gggaaatccc caaaggagat acaggcgttc
    23941 ttccaaaggg cgtcggactt cctcattggc cgggtaggac gggaaaatat cgtgtcggcg
    24001 gtggtacaca tggacgagaa aacgccccac ctgcatttga cctttgttcc gctgacaaag
    24061 gacaaccgcc tgtgcgctaa agagattatt ggcaaccggg caaacctgac gaagtggcag
    24121 gacgattttc acgcctatat ggtggtgaaa tatcccgact tggagcgtgg ggagagtgcc
    24181 agcaagacag gccggaagca tatccccacc cggcttttca aacaggcggt ttccctctcc
    24241 aaacaggcca gagccattga agccgccctt gacggcatta acccgctgaa cgccggaaag
    24301 aaaaaagagg aagccctctc catgctaaaa aagtggttcc cgcagatgga gaacttctcc
    24361 gggcagttga aaaagtacaa ggtcacaatc aatgacctgt tggcggagaa tgagaag
//
LOCUS       DAMKOJ010000054        24137 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000054 DAMKOJ010000000
VERSION     DAMKOJ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24137
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.056"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            77..151
                     /locus_tag="PC592_002406"
     tRNA            77..151
                     /locus_tag="PC592_002406"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:109..111,aa:Thr,seq:tgt)
     gene            complement(299..976)
                     /gene="srtB"
                     /locus_tag="PC592_002407"
     CDS             complement(299..976)
                     /gene="srtB"
                     /locus_tag="PC592_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HDF4056366.1"
                     /translation="MKKLYRIIINIILILVILYSGFNIYSKLSKYNHDTKTSSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSLDDKNVIIYGHNMKNKTMFNNLNKFKDADFFRQNNKIKINLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNSESDYQNYINDITSKSLYKSPIKVDINDKIITLSTCTYEFDDARM
                     VIHGRLI"
     gene            1108..1442
                     /gene="rnpB"
                     /locus_tag="PC592_002408"
     ncRNA           1108..1442
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PC592_002408"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            1720..4254
                     /locus_tag="PC592_002409"
     CDS             1720..4254
                     /locus_tag="PC592_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HDF4056367.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSEKRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVSNNVEGNNEQDRLEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKLSDVDSKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEGYGFDKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAYNLIKDDYSELENHEIALKRTRKNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDVEEETKEEVASNNQDIDNFVEDKDITDKEYDSNKEDIIE
                     SENKKSKKKAKLFGFIKKDNEEVEQEEENLNGISSDVILDEPIENNRVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSLNNESKLEKESRNLEDEKVKEEKLE
                     NEKSVVIPINKKENSNKKSKNSSKDKSREHRKDAKNYVSDKEDSLDDEDVVSKKNRLK
                     ETIIAVVIVVIVGVGYFITVGNNKKNDKEDIPKSSTQQQANNKLTEEEKKAQAEKEKK
                     EAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGIYYTVYAGSLKVEKTAKETAKEYEA
                     KGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLEELK
                     ESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            4375..6366
                     /locus_tag="PC592_002410"
     CDS             4375..6366
                     /locus_tag="PC592_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056368.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNKDTGVKYIYSFSDHKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKLYMGGINKDNEKFIFISGKNRFEVN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCDIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLNDIENETVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKILLNLSKNMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEHRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            6356..6676
                     /locus_tag="PC592_002411"
     CDS             6356..6676
                     /locus_tag="PC592_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056369.1"
                     /translation="MSSKYNVWNFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSDLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYIDEDIDSDIKGI
                     LDEI"
     gene            6874..7743
                     /gene="galU"
                     /locus_tag="PC592_002412"
     CDS             6874..7743
                     /gene="galU"
                     /locus_tag="PC592_002412"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF4056370.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIHCAKSFIGDEPFAVLLGDDIVDSEVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFNILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            7767..8780
                     /gene="galE"
                     /locus_tag="PC592_002413"
     CDS             7767..8780
                     /gene="galE"
                     /locus_tag="PC592_002413"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDF4056371.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNLIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHIVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLATGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            8892..10826
                     /locus_tag="PC592_002414"
     CDS             8892..10826
                     /locus_tag="PC592_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HDF4056372.1"
                     /translation="MKKSLKQYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKIIDGKTYYFNSDGVMQTGWQEKNGKKYYLGADGLSV
                     TGWQEIDGNKYYFDKTGIMQIGWQQIEGKSYYLDKDGKMLTGAQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTDNLPNETVEEMKLLAPKTVILIGGENAISSKLEQEIKTIFNAETKRIAGQDR
                     YQTATRIAEELGSREEIKTAYIVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAISDSVIARMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDADLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMYNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILGK"
     gene            10981..11844
                     /locus_tag="PC592_002415"
     CDS             10981..11844
                     /locus_tag="PC592_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HDF4056373.1"
                     /translation="MVSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPII
                     EPVGPWLEKMR"
     gene            complement(12052..12933)
                     /locus_tag="PC592_002416"
     CDS             complement(12052..12933)
                     /locus_tag="PC592_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4056374.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPTKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYF
                     PPAIKNFKSFVIKNAQL"
     gene            13346..14194
                     /locus_tag="PC592_002417"
     CDS             13346..14194
                     /locus_tag="PC592_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDF4056375.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGTEEDRTEAQREKEKNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTADDLAPIPADKIVSIQVCDVLENPYEKLRDESLHDRLA
                     PGEGFGNTEEFVKIIKEHNILPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14273..16195
                     /locus_tag="PC592_002418"
     CDS             14273..16195
                     /locus_tag="PC592_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF4056376.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YIERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKIAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEIHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVLGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPISCLANPILGHEAEFKSAEISKEVLVVGGGVGGML
                     ASWICAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDAVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHDVTVIELREEVGADVISEHRKFLMNDFENYNIHTVTSAKVA
                     KFYDDGVDYLLADGTEHDLKGFDSVVLAMGSRNYDPLSEVIKELVKETYVVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            16277..17140
                     /gene="aroE"
                     /locus_tag="PC592_002419"
     CDS             16277..17140
                     /gene="aroE"
                     /locus_tag="PC592_002419"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF4056377.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFEKLDLDYRYLAFDI
                     TVDKVKEALSAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENEVEVKGKKVTIMGAGGAATAIQVQCALDGAREISIFNAKDDF
                     YKRAEQTVENIKKEVPKCIVNLYDLEDTNKLYEEIESSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPRKTKMIEDAESNGCKAIGGLGMLLYQGAESFNLYTGLEM
                     PVKEVNELCFK"
     gene            17342..18559
                     /locus_tag="PC592_002420"
     CDS             17342..18559
                     /locus_tag="PC592_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4056378.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYIFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            18795..20660
                     /locus_tag="PC592_002421"
     CDS             18795..20660
                     /locus_tag="PC592_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF4056379.1"
                     /translation="MENVFKRLQEFDGYDGYKESFEMNYLCIYENIPLREQVELANNL
                     IDGILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLDVENLREVVDTFSKSGEYVFYLSNAIKKIEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEYGYKDTKYQRLLMNYIISIVDLNEYLE
                     KRDLDREKINNLSLLICNYLLSVEFKYIGNKLELVNRFLPIVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKVEFEKEINDILLSEKWKSIYFEALKDASGKTEDMIKMSEIYNVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLDFFEKTFKVDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKVVKEAYEKEKNIILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSITV
                     AGSRFRNREYLEKELEKSKIYYLIREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(20838..22202)
                     /locus_tag="PC592_002422"
     CDS             complement(20838..22202)
                     /locus_tag="PC592_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4056380.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDISIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEVDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGISVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKEQASKIKDKSDVKIPSKF
                     KIIK"
     gene            complement(22380..23723)
                     /locus_tag="PC592_002423"
     CDS             complement(22380..23723)
                     /locus_tag="PC592_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF4056381.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(23796..23897)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
BASE COUNT         9525 a         2679 c         4167 g         7766 t
ORIGIN      
        1 ttattaaaat atatatgtag tttttagagt gttaattcta aaagttagct ttattaattt
       61 ataatagaat aagtgtgctg gtgtggctca acggtagagc agctgacttg taatcagcag
      121 gttgtaggtt cgattcctat caccagctcc agtaaagact atgtttttag catagtcttt
      181 ttttattgtt taatgtgtct tttattttgt actacatatt tttattagcc taatataaat
      241 tattggaaca aaagatgaca cagtttaaaa ttattgtttt aaactgtgcc tgtgagtttt
      301 aaatcaatct accatgaatc accattctgg catcatcaaa ttcataggta catgtagaaa
      361 gtgtaattat tttatcatta atatctactt taataggaga tttatacaat gatttagaag
      421 taatatcgtt tatgtaattt tgataatcag attcactgtt aaaatttgtt tttagataat
      481 cataatcaga ctctacaata taagcagaaa aaacatcata taaaaattct tttccattta
      541 agtttatttt tattttatta ttttgtctaa agaaatcagc atctttaaac ttatttaggt
      601 tgttgaacat agttttattt ttcatattat gtccatatat tatgacattt ttgtcatcaa
      661 gagatttatt tctataatcc ataaatagtg tacctgaaat agaatctttt ttataaaaat
      721 ctttgtcaag atagtaagaa ttatctttag attgtacaac tggatagttt atatttgtat
      781 tctcaacaga aagccaaaat ttaaaatcac tgttaatctt tgataagtcc tcttttttat
      841 attctttttt ttgaagttct gaggatgttt tagtatcatg attgtatttg ctaagttttg
      901 agtatatatt aaatccactg taaagtatta ctaatattag tataatgtta attattattc
      961 tatataactt tttcaatata tcacctcgag ttaaatgtag tttatatacc tatattacac
     1021 tatttttgaa taaatttaaa tttttagtat aatattactt tgacatgtaa aagaatttgt
     1081 gttaacataa ctaagtaaaa taaatattaa gtaagccaga taatcgcatg taattttaca
     1141 tgaggaaagt cggagctcca tagagcaggg tgctaggtaa cgcctagtgg gagcgatcct
     1201 aaggatagtg caacagaaat aaaccgccaa cattgtggta aggatggaaa ggcgaggtaa
     1261 gagctcacca gcagctaggc gactagttgg ctatgtaaac cccacctgga gcaagaccaa
     1321 gataggaata aagagtgctg ctcgtactct ccggtaggta ggtcgcttga gcctattggt
     1381 gacaataggc ctagaaagat gattatctaa tacagaactc cgcttataga cttgcttaat
     1441 tattttgata atcaaaaaca tcagtttaaa ctgatgtttt tttatttgta aatttgtcta
     1501 atctactttt aaaattttga ggaatattgt aatataagtt agtacagata ttaaaaatgg
     1561 tataatataa gatagatata aaaagaaaaa gtaaaatgat gtaaataata tgatatgata
     1621 taagatgtag caaatttagt aaataattat ttaaatatca taatcaaatt agcaactttg
     1681 cacaatgtaa atattacaat aaaataattg atttaaggag tgaaggtttt gagtgaaaat
     1741 aatataataa gaaacactgt tttaaatgtc acagcaagtt ttttaaaaca agagtctaaa
     1801 ataaatgaaa agctagatgg tgttttggaa aagaaatttg aaaaagtaga atttaatgaa
     1861 gcaaaatatg cagagctttt aaaatttaat atattgtttt ataagacatt agcaagaaat
     1921 acagaaccac tgattggcaa atggatagta gataagtaca tacctgaaat agatgaatta
     1981 gaaaaggatt tagaattaac tacagcaaaa tgtagaaagt atgtaaataa ggctatgaaa
     2041 gagggattag actctctaaa agccaatgat ttaaatagtt ttttagctta tgataaaatg
     2101 gaactatcag agaaaagacg acgtttagaa aaggattata aggttttaaa cctatacaaa
     2161 gaccttctca atatatctct tagaaaaata agtttagaaa agaaagaatg tggagattta
     2221 tttcttaaaa atcaagcaga tgctaaaaga gaattaaaaa gagaaatcat attctgtgta
     2281 aacaaaatat tggctagtaa taaagatgta gtgtctaata atgtggaagg aaataatgaa
     2341 caagatagat tagaaataaa agcaactgaa attgaggatt tgcaattagg taaagataat
     2401 tcagaaaatg atatgctatt aaatgaaatt aaaaattcaa aagtaaaaca tgaatcaaaa
     2461 ttaagtgatg tagattcgaa gtttatagat aagctaaata gcttaaataa tgaaagtata
     2521 tctcaaacaa tacacaatga atataagaag ttatgtggat tagaagaact tcattctgtt
     2581 gaaggatatg gttttgacaa agaaattatt aaggattttg cctgtgcaac agttgtatta
     2641 gaatttttaa agagaagaaa tagagacctt atagaaggtg caatgagact gactataatt
     2701 ggagaatttg gtcctgaaaa ttttaaggaa tttgtagact atgtaattaa aaataaaaca
     2761 gaaattagtg aagatacgtg gaataaagca tataacctaa taaaagatga ctatagtgaa
     2821 ttagaaaatc atgaaattgc attaaaaaga actagaaaaa ataaagatat cgatattgaa
     2881 gaatacattt acatgataaa aaatgcagat aaagatattt gctttagaag tagtatttca
     2941 atagaagatg atgttgaaga agagactaaa gaagaagtag ctagtaataa tcaagatata
     3001 gacaattttg tagaagataa agatattaca gataaagagt atgatagcaa taaagaagat
     3061 ataattgaat cggaaaataa aaagagtaaa aagaaggcta aattatttgg atttattaaa
     3121 aaagataatg aagaagttga gcaagaagaa gaaaatttaa atggcatttc ttctgatgta
     3181 attttagatg aaccaattga aaataatcga gtaaaatcag aagaaataga gcaaaatgaa
     3241 ctaaaagaaa taaaacaaga agaaccaagt caacatatag aagaagaacg tagtgtaaaa
     3301 atagaaaaac caataaataa taatttagat gaaaaggtat ctttaaacaa tgaatctaag
     3361 cttgaaaaag aaagtagaaa cttggaagat gaaaaagtaa aagaagaaaa attagaaaat
     3421 gaaaaatcag tagtaatacc tattaataag aaagaaaata gtaataagaa atctaaaaat
     3481 tcttctaagg acaaatctag agaacatagg aaagacgcga aaaattatgt atcagataaa
     3541 gaagactctt tagatgatga agatgttgtt tctaagaaga atagattaaa agaaactatt
     3601 atagcagtag ttatagtagt gattgttggt gtaggatatt ttataacagt aggtaacaat
     3661 aagaaaaatg ataaagagga tattccaaaa tcatcaactc agcaacaagc caacaataaa
     3721 ttaactgagg aagagaaaaa agcacaagct gaaaaagaga aaaaagaagc agaagaaaaa
     3781 gcaaaagctg aaaaagaggc tcaagaaaaa gcacaagctg aaaagaaagc aaaggaaatg
     3841 gaagcatata aagatggtaa aggtatatat tacactgttt atgcaggttc acttaaagtt
     3901 gaaaaaacag caaaagaaac agcaaaagaa tatgaggcta aaggtatttc ttcaacaata
     3961 attcaagaaa atggatacta taaaataaaa ataggtgatt attctcaata tggagaagca
     4021 caagaaaaat gtaatgaact agctaaaaag tctattgata catatatagc tatgtatgat
     4081 aagtactatg attataaatt agaagaatta aaagaatcag ctccttcttt gagtgctgaa
     4141 gaacttaaac aaaaatatga agatttaaga agtgagttaa agaataaatc tggatatcgt
     4201 gaatatgtta aacatttaga taaactttat gaagaaatag ttgaaggtgc ttagagtatt
     4261 ataaaaaagg agaaactatg tctcagaata aaaagtataa aaaaatatta tttattttga
     4321 gacattttgt tcacctttat aaaatactta taattctgtt taggtggtga aggtatgttg
     4381 aaattaggag aaaaaatcat atatgagctt tcagatggat ttgagcttag tggtatcagt
     4441 agatactcaa aagaatataa aaagcttcat ataacaaatc tagggaatat aataatcagc
     4501 aaatcagatg aagttaataa ggatacaggt gtaaaatata tatatagttt ttcagaccat
     4561 aaggaaaaat tagaggcagt tttagaagat tctcaaataa ttgtctatgg aaataacttg
     4621 cctttttaca taaaaagtga aaattcaagt aaaaatgtta cagcaaattt aactatgaaa
     4681 ataactttgg atgaatatga tttaatttgc aaaagccaaa gagagtttat attttatcta
     4741 aaggataata tgactatatt aagtttagat gacaataagc tttatatggg tggaattaat
     4801 aaagataatg agaagtttat atttatcagt gggaaaaata gatttgaagt aaattttgat
     4861 gatatagaaa ggtatatttt agaagataaa agagtgtcct tgaagggata ttttcatatg
     4921 gaaagagagg ggattatagt aaggtctgta tctatattta ataacaatat agatagtgta
     4981 gttccatctg atttaaatga gagagttaaa gataatcaaa aaatagggaa ccttcctaaa
     5041 gattgtgata tagtgttctg caagatatca ggaaatatag atggatttga ttataaaaac
     5101 acaaacatgc ttttagtaaa atatcaagac caattaattt ttataaataa gaaatctaaa
     5161 aagactattg taaagtcagc aaaagataat tgttcaaagt taaatttggg agaagatata
     5221 atcttatatg ataataaaaa tgtatttaac ctacatataa atgataaaaa tagagaaatt
     5281 atgcaaatag atgatttaaa tgatatagaa aatgaaacag tgggatatac attaaaacat
     5341 gctccatttt ttattcaaga agatttcgat agcttgacta ttctaaagtc ttttcaaaaa
     5401 gaaatcatat ctataaaaaa tagtgatata aaagacattg taattaataa agagcttgaa
     5461 aacgaaaatt ctaattttgt agaaacagaa ataaaattta ataatcaaaa aatactttta
     5521 aacttaagta aaaatatggt tcaaaaactt atgcaagatg tatttatata tgcaaagcaa
     5581 cctctactta aagaaaattc tattgaagtg atatataaga attggtctaa agctatgaat
     5641 gatatgataa tatttaattt ctttggaaat atttattata tgaaatctga atttgataag
     5701 attttagaaa aagaattaaa tgatgaaata agaatagaag ttataaattc actttataag
     5761 caaatacaag aacacagaaa caatttagat ttattgtcag catatatgcc aagaatatta
     5821 gaaaatcaag aaatagattt gtttgaaaag tataatacta aacttgatgt acaagtgttt
     5881 aagcagatta aaaatctatt gtctgactta tcatataata taagtagtta tttaaatgaa
     5941 gttgaaaaaa gcttagacaa tatcatcttt gtaatttcag gagaagataa gaagaaatac
     6001 aactatagaa tgttaaaaga aagtgaaagt gcaagtcttg atgtattttt aaaacaagct
     6061 atatcaagat taaatcattt agtagaaaat atgtatcctt attatgtaga tgaaactagt
     6121 agggaaatgt ttaagttatt tgagttattg tggaaaaact atagaaatat tgatgatgat
     6181 agtataaaag aaatattatt cgagagaata acaaatacat atgtatttaa acaattgaca
     6241 ttaaataata gtacaaaaga aagaagaaaa gacataattg aaaaaatata taattctgtt
     6301 gattatggaa ccaataaact agatgaaaat atgtttttca caggaggaat aaaatatgtc
     6361 aagtaaatac aatgtttgga attttaacta tgagttctta ggcttggact caggagatga
     6421 aaaaaataat gaagtttatt atgagattga tttagatgaa attttaaatg aaaactatat
     6481 agatgaagat atagatagtg atttagattc tgatggaaat agtattttag gagaattaat
     6541 atcagagatg gatatagatg aagatgtcag tgttgatatg acatatcaag aactagaagt
     6601 tgacttagaa gatttagatt cttatataga tgaagatata gatagtgata taaaaggcat
     6661 cttagatgaa atttagtacc tgtataagtt ttagataaaa tataaacaat acaatattaa
     6721 cttataaaac taaaggtaga tgaaatttca tctaccttat attatcttat agcattaaat
     6781 attgggataa tatagagttt gaagaaaaag tataaatatg gtatattaat ttggtacaat
     6841 agaaaattta cgaagaaggg tgaaaaaatg cagatgacag ttaaaaaagc gataatacca
     6901 gcagcagggc taggaactag atttttacca gcaacaaaat cacagcccaa agaaatgctt
     6961 cctatagtag ataaaccaac tttacagtat ataatagaag aagctataga atcaggaatt
     7021 gaagaaattc ttataataac aggtagaaat aaaaaatcta tagaagatca ttttgataaa
     7081 tcagttgaat tagagttaga actagagcaa aaaggtaaga cagagatgtt agaaatggta
     7141 agagatatat caaatatggt aaacattcat tatataagac aaaaagagcc aaaaggtctt
     7201 ggacatgcaa ttcactgtgc aaaaagtttt ataggtgatg aaccttttgc tgtattatta
     7261 ggtgatgata tagtagattc agaggttcca tgcttaaaac aattaataga tacttataat
     7321 gagtataaaa caactgtatt aggtgttcaa aagatagcta aagaagatac taataaatat
     7381 ggtatattgg atgtaaaaca tatagaagat agggtatata aagttaaaga tatggttgaa
     7441 aaacctgcaa ttgaagaagc tccatctgat atagctatac ttggaagata tataataact
     7501 cctgcaatat ttaacatatt agagaaacaa acacctggta aaggtggaga aatacaactt
     7561 acagatgcac ttcaaactct tggaaaacaa gaggctattt atgcttataa ctttgaaggt
     7621 agaagatatg atgtgggaga taagattggt tttttagagg caacaataga ctttgctcta
     7681 aagagagaaa atttaaaaga tgatttaatg gactatatga gaaaaaaagt aagtgaaaaa
     7741 taaatattag aaaagaggta attacaatgg cagttttagt agctggagga gcagggtata
     7801 taggaagcca tacagcaata gaacttttag aatcaggtta tgaagttgtt atagttgata
     7861 acttaagtaa tagtaactta atagttgttg atagaatcaa ggaattatca aaaaaaccag
     7921 taaaatttta taatattgat atcagaaata aagatgaaat gcatattgta tttaaagaaa
     7981 ataatattga atcaattata cactttgcag ctttaaaagc agttggcgaa tcagtagaaa
     8041 aaccaattga atattacagc aataatctaa taagtacctt aaatttattt gaattaatga
     8101 gagaatatgg tgttaaaaag tttgtattta gttcttcagc tactgtatat ggagacccac
     8161 acacttgtcc tatattagag gattttccac tttctgtaac caatccatat ggaagaacta
     8221 aacttatgat agagcagatg ttggtagata tatcaaaagc agataagtca ttggatatag
     8281 ctcttttaag atactttaat ccagtgggtg ctcataaaag tggtagaata ggtgaagaac
     8341 caaatggagt tccaagtaat ctaatgcctt atataacaaa aatagcagta ggtaaattga
     8401 aggaattaag tgtttatggt aatgactatc caacacatga tggaactgga gttagagact
     8461 atatacatgt attagattta gctactggtc atgtaaaagc attacaaaaa ttagaagaaa
     8521 atccaggact tgttgtttat aatttaggaa ctggaaaggg atatagtgtt cttgatttag
     8581 taaaagcatt ttctaaagca agtggaaaag aaataccata taagattgta ggaagaaggg
     8641 ctggagatgt agccatgtgt tatgcagatt cttcaaaggc agaaaaagag cttggatgga
     8701 aagctaagta tgaacttgaa gaaatgtgtg aagattcatg gagatggcaa agcatgaatc
     8761 ctaatgggta tgaggaatag aatgtatgct tatatgtata aatgtaacaa atttgtaaat
     8821 ataaggtatt ggtaatttta tgttataatt agacacatgt agtaatgttt ctaaaagagg
     8881 gggaagttgt agtgaaaaaa agtctaaaac agtatttagt actagcactg actttagttt
     8941 tagtatttgc atgtggcgta ccagaatcaa gtgcagccag taaacatgtg attatagtaa
     9001 attcaagaaa gaacactcta ggatattttg taaataataa acttgtaaaa gaatttagag
     9061 ttgcaacagg taaaaaaggg tcagaaacac caacagggaa aacaaaagta gttaacaaga
     9121 taaaaaacag accatattat aaaggtaata tacctggagg aagtccaaga aatccattag
     9181 gagatagatg gatgggatta gcattaaaag gaacttatgg agatacatat ggaatacatg
     9241 gaaataataa tgagagttct ataggaaagc atatttctgg tggatgtata agaatgcaca
     9301 ataaagatgt tagatggtta tttgaccaag ttcctgtagg ttcagatgta attatagatt
     9361 atagtaatga cagttatgta aagatagcag caaaatataa gataaattta aaccaaacag
     9421 gatggaaaac agaaaacggt aaaaagtatt atgtaaaatc agatggaaca taccaaaaga
     9481 atagttggtt aaaagtaaat gggaaaatgt attactttga tgcttcagga gtaatgcaaa
     9541 caggatggaa aacaattaat aacaaaaaat attatttagg aactgacgga gcaagagtat
     9601 ctggatggaa aataatagat ggaaagactt attactttaa ttcagatgga gtaatgcaaa
     9661 caggatggca agaaaagaat ggaaagaaat actatctagg agctgatggt ttatcagtaa
     9721 caggatggca agaaatagat ggtaataagt attactttga caaaacagga ataatgcaga
     9781 taggatggca acaaatagaa ggtaagtctt actatttaga caaagatgga aagatgctaa
     9841 ctggtgctca aaaaatagat ggaaaagatt atacttttaa tgaagatgga actataaatc
     9901 ctacatggga tacaattata ggtgcaaata gatttgatac agctaagaag ataagttcag
     9961 ttggaaactg gaatgctgat agttcagata ctgtaatatt agtaaatggt aatgcaatag
    10021 ctgatggtat aacagcaact cctttggcaa gtagctatga ctcaacaata ctacttacta
    10081 atacagataa tttaccaaat gaaactgttg aagaaatgaa gttattagca cctaaaacag
    10141 taattttgat aggtggagaa aatgcaataa gttctaaatt agagcaagaa ataaaaacta
    10201 ttttcaatgc agaaacaaag agaatagcag gtcaagatag atatcaaact gctacaagaa
    10261 tagctgaaga acttggaagt cgagaagaaa taaaaactgc atatatagtt tctggaaatg
    10321 gggaagcaga tgctttatct gtagcttcta aagctggaga agaaaaacaa cctataatat
    10381 tagtcaataa agatggaatt acagaagaat cttataaatg gctaacagaa agaaaattag
    10441 aaaatgcata ctttataggt gggccaagtg caattagcga ttcagtaata gccagaatga
    10501 atgatataac tactgaagat atttcaggaa atagaatata tggagatagt agagtagata
    10561 ctaatgcaaa agtaatagaa aaattctatg gagatgctga tttacaggct gtattagtta
    10621 gtaaatcaga tgctttagta gatgctttat cagctggacc attagctgta aaattacatt
    10681 caccaatagt tttaatgtat aattcaggat tatcgtcaga gcaacaaaga gtatttgcaa
    10741 ataaaaaagt tgaaactcct tatcaaatag gaggcggagt atcttatata gtaatggata
    10801 aattaatgga tattcttgga aaatagtgaa aatatatact gaaaaataat tgtaattgag
    10861 atgtgaaatt caatcaataa aagcttgatt gttttacatc tcaatttttt agtataaaat
    10921 taagtttaag ttatataaaa atcttggaat atttttaaaa ctcatataaa atgaatatag
    10981 atggtatcat catatgttaa gagggtgagt aagattataa agaaaaaata tataatgttt
    11041 attgatgaaa gtggaagagc tgatataaat catgaagacc catttacatt gacaggagta
    11101 atttttgaat ataaatatgc agtaagtcaa ggcgattatg tatgttcttt gaggaaagaa
    11161 atggacgcat ttaaagaata ttgttttgga actagcaaca taggaataca tttgacagat
    11221 atatcaagaa aatcaagagc ctttgagaag tttgatgatt cacagattaa gttattttat
    11281 gatgagttgc ctttatttct atctagacta gaatgtacta taatatcagt aacagtagat
    11341 aaagctagat taaaaaaata ttatgcacct tcaaaggaac cgtatgttgt ggcttttata
    11401 catgttcttc agaattttta ttcgtttgta aataatgaaa ctgtagaatc tgcacgaata
    11461 gttatagagt caagggatga tgtctcaaac ttaaaagtac aaaaggcgtt ttttgatgta
    11521 tttaataatg gaacaatata cttagatata gatgaagaat taagagataa ggttaaaggt
    11581 tttataattg ccaaaaaaga agatgcagac tatagagaag gtttagaaat agcagatatt
    11641 ttatgtaatc ctcttagcag agcaagaaga gggctaatag aagctaatcc aaagtgtatg
    11701 caatatggag aaaaaaataa aatattcaaa tctgtcagaa ataaaatata taccccaacg
    11761 agtgtgaatg atataagaaa ttggggtttt aaagaagttc ctattataga gcctgttgga
    11821 ccatggcttg aaaaaatgcg ttagatacaa ttgacaagtt ttaaaaaatc tgatataata
    11881 aaaataacat agttattcag gaactgaatc cagttgctgt tgtataacga taattactga
    11941 gactcggata ccgactgtca gttaggaatc tatactttta aaagtataga tttttttatt
    12001 ttataaaaag aataaaagag gatatttaaa aataacctct ttattaataa attatagttg
    12061 cgcgttttta atgacaaagc ttttaaagtt tttaattgca ggagggaaat atctatcttt
    12121 tataaatgcc aagtaaaagt ttctttccca acttgggtga ataatctgaa ttacttttac
    12181 ttttgtaaag ctaagcatat tcatatttgg gactacagca attccgaaat tttttgcaac
    12241 taatccagca attacttggt cttcttccac ttcatagact atgttaggct gttgatttat
    12301 ttttttaaac atatcatcaa ttatatatct aagaccactt ctctgattaa atactatttg
    12361 aggataaggt atggtttctt ttaaatctat agtatccttt gcagctagtg gatgactata
    12421 tggtacaatt agtactaagt cttgtttggc aacaggtata aattcaattc ccttttcttt
    12481 ttcaagtttc gaacaaaatg caatatcata ttttctttct ttaagacctt gaataatgtc
    12541 agtagttaca ccagtatgaa atttaaaatc tattgattta gtaggattag attttaaaaa
    12601 tttatgcact atatctggga taaagtcagt accaagtgtt ctaagaaaag ctaagtctat
    12661 ttgtccttca ccagtaccgg ttatttttaa tgattttaca cttgaatcta aaatttctag
    12721 cgatttttcc acatctttta aaaatatttt tccatactta gtaaggacta tatttctacc
    12781 ttccttttca aataaagcta ctccaagttc attttctagt aaagaaatag catgacttaa
    12841 gcttggttgt gttatagata aattttctgc tgcttttgta tagtgttcta aatgtgctaa
    12901 tgtaacaaaa tagcgtaagt gatataaatt caatttttgt tcatcctttc atagatattt
    12961 ttctttatat atttgtagaa gttgaacttt aagatatttt ttacattttt attatatatg
    13021 attatgtagt aagaataaaa gcttttaaaa aaatttatcg ttttttgtct gaattataag
    13081 ataaagatat ttatacgaca tagtagaaaa atacaagaat tatcttataa ataaaatcta
    13141 taaacaaaat ctatgaatta atagtgaatt atcaatttgt tattagtaaa gtctcatgat
    13201 acaataaatt tataaaatct agataaaaaa aatcaaaaaa tagttttgtt ttttaagtaa
    13261 aataatacta ctagtagaat aaataaaaat ataaaatcaa aaatactatt gtttataaag
    13321 aaaataaagg gggcaaattt aaattatgaa taatcaaaaa aatctcaata ttccaattac
    13381 aattagttct tatacattag ggacagaagt ttcattccgt gatagagttc gtattgcaaa
    13441 agaagctgga tttgatggta ttggattacg tgctgaaaat tatattgatg caaaaaatgc
    13501 aggtgttaca gatgaagaga tgattgcaat tcttaatgaa tatgatatga aagttacaga
    13561 agtagaatat ataactcaat ggggaacaga agaagataga acggaagctc aaagagaaaa
    13621 agagaaaaat gtttatcata tggctcactt atttaatgtt aaacatataa attgtggatt
    13681 attagagatg ataccagaag aacaaattat aactgcattg ggagaattat gtgacagagc
    13741 aggtgaactt attataggtc ttgagtttat gccatatagt ggtgttccag atttggctac
    13801 tgcatggcgt gttgtgaaag gatgtaatcg tgaaaatgcg atgcttatat tggatacttg
    13861 gcactgggct agagcaaagc aaacagcaga cgaccttgca cctattccag cagataagat
    13921 agtatcaatt caagtgtgtg atgttttaga aaatccttat gaaaaactta gggatgaatc
    13981 actgcatgac cgtttggctc caggtgaagg atttggaaat acggaggaat ttgtgaaaat
    14041 aataaaagaa cacaatatat taccaagagt cataggggca gaagtaatat ctgattctct
    14101 aatatctaaa ggattatcta ctgctgctga aactgtattt aatgcaacta aaaaagtttt
    14161 ggataaagca tggtctgaag tatctccaaa ataaacttat acaatataaa aatatacgaa
    14221 gtattataat ataaaacttt taaatataaa acttgaaagg aaggaaaatc ttatgaagat
    14281 tagttctatg tttacaccta taagaattgg ttcaatgaca gttccaaatc gttttgtagt
    14341 tcctcctatg ggaaacaatt ttgcaaacac agatggtact ttaagtgaaa cttctaaggc
    14401 ttattatatt gaacgtgctt taggtggctt tggattaata actatagaat ctagtgttgt
    14461 agacaaaaaa gcaaaaggag gtcctcgtaa gccttgttta tatgatgata gcacaataga
    14521 tagttttaaa aatgtaatag atgcttgtca tgatgcaggt tcgaaggtat ctatacaatt
    14581 acaacacgct ggttctgaag gaaatgaaaa aatagcaggt catccattaa aagctgcttc
    14641 tgcaatacct gcatcaaacg gccgtaatac accattagca ataacaacag aagaaatata
    14701 tgaacttata gaatcttatg gagatgctgc attacgtgca caaaaagctg gtgcagatgc
    14761 tgttgaaatt cattgtgctc atggatatct agttagtagt tttatatcac aaaggacaaa
    14821 taagcgtgta gatgagtttg gtggatgttt tgaaaataga atgagattac ctcgtcttat
    14881 cattgaaaat atacgtaaaa aagtaggcaa ttctctagca atattatgtc gtataaatag
    14941 tactgatgat gtactaggag gaattgatgt acatgatagc tcagtaatag cagcatatct
    15001 agaagattgt ggaatagatg gacttcatgt ttcgcgtagt atacatatac atgatgaata
    15061 tatgtgggct cctacgactt tacatgctgg attcagtgca gaattagtta ctgaaataaa
    15121 aaaagctgtt agtataccgg taataacggt tggacgttat acagagccac agtttgctga
    15181 attaatggtt agacaaggaa gatgtgattt agtagcattt ggtagacaaa gcttagctga
    15241 cccagaaatg cccaataaag ctaaaaatgg aaagctagac gaaatgatac catgtattgc
    15301 atgcttacaa ggatgtgtac caaatatgtt ccaaggtaaa cccatatctt gtcttgcaaa
    15361 tcctatatta ggacatgaag cagagtttaa gtcagccgaa attagtaaag aagttcttgt
    15421 tgttggtgga ggcgttggag gtatgcttgc atcatggata tgtgctaaaa gaggtcacaa
    15481 tgtaacttta gttgaaaaat ctgaagttct tggtgggcaa atgcgtttag ctgcatatcc
    15541 cccaggaaaa ggagatatta ctaacttagt tagaagttat atttcaaaat gtaatcaata
    15601 tggtgtaaaa atatgtacta acacagaagc tacagtagaa cttataaaag agaaatcacc
    15661 tgatgcagtt attatagcta ctggggcaac tccacttgta cttcctatac caggaatcaa
    15721 tgattcagga ttaatacatg ctgtagacct tcttgatggt aaaaaatctt gtggtaaaaa
    15781 agtacttgtt gttggtggtg gaatggttgg atgtgaagtg gcagctttcc ttggagaaca
    15841 agaacatgat gttactgtta ttgagcttag agaagaagtg ggtgcagacg taatttcaga
    15901 acaccgtaaa ttccttatga atgattttga aaattataat atacatactg ttactagtgc
    15961 aaaagttgct aaattttatg atgatggtgt tgactattta cttgcagatg gtacagagca
    16021 tgatttaaaa ggttttgact cagtagtact tgcaatgggt tctcgtaatt acgacccatt
    16081 aagtgaagtt ataaaagaac ttgtaaaaga aacttatgtt gttggtgatg cagtaaaagc
    16141 tcgtagagca ttagatgcaa caaaagaagc ttttgaagta gcattaaata tataaataat
    16201 aaataaattt ttctttgtaa ataactgaat aggttatttg caaagaaaat gataatattg
    16261 ggaggaaatt agagttatgg aaatttcagg tagaacagga ttatttgcat taataggtac
    16321 accagttggt cactctaaat caccagtgat gtataattat agttttgaaa aattagattt
    16381 agattataga tatttagctt ttgatattac agtagacaag gtaaaagagg cactttcagc
    16441 aataaaaact tttaatataa aaggagctaa tgttactatg ccatgtaaat ctgctgttac
    16501 agaatatatg gatgaacttt ctccagcagc tcgtataatt ggagcatgta atacaattgt
    16561 aaatgacaat gggaagttag ttggtcatat aacagatggg gtaggctatg ttcgtaattt
    16621 aaaagaaaac gaggtagaag ttaaaggtaa aaaggttaca attatgggtg ctggtggtgc
    16681 agcgactgct atacaagtac aatgtgcatt agatggagca agagaaatat ctatcttcaa
    16741 tgctaaggat gatttttata aaagagcaga gcaaacagtt gagaatataa aaaaagaagt
    16801 accaaaatgt attgttaatc tatatgattt agaagataca aacaaacttt atgaggagat
    16861 agaatcaagt gatatattga caaatgcaac tcttattggt atgaaacctt atgacaatga
    16921 aacaaatata aaagatacta gtgttttgag aaaggattta gtagtaacag atgttgttta
    16981 taatcctaga aaaacaaaaa tgattgaaga tgctgaatct aatggatgta aggctattgg
    17041 tgggttagga atgttattat accaaggagc agaatctttt aatctatata ctggattaga
    17101 aatgcctgta aaagaggtta atgaattgtg ttttaaatag agataaaagt gattgcttaa
    17161 acaatggaaa aacatatgta tttcaatgtt tttagtaata aatttcaaat tgtcatagtg
    17221 ggttttgcat tatagtctag ttaaatttga agttttaact gactatgctt taaacccatt
    17281 atggggataa gtttattgta cacaaaaatg ttaataaatt aacaaggata ggagaagaac
    17341 tatgaacaat aaaaaatatt atcctactgc catagcgttg tatttttcat attttttact
    17401 tggtattgga atttcaattt taggacaata caaaccagaa ttttcatcaa tgtggggggc
    17461 taaaacacta tcagatggaa cattggatgt aagtattgtt ttagctgtta ttgctgcact
    17521 aggattaggg agacttatat cgtatccatt tgcaggacct atttcagata agtatggaag
    17581 aaaagtaagt ggtcttatag gaaactttct acatgcaatt ttctttgttg gaattgtatt
    17641 ttcaccaaat ttttatatag catatatatt tgcaataatt ggaggggcag caaattcatt
    17701 cttagatacc tgtgtaacgc cttcttgtat ggagatattt gctagtttag gaacaatagc
    17761 aaatatgttt actaaattta caatagcttt agcacagttt ttgcttcctt ttataattgg
    17821 atttgttgca gcaaattcaa tatcatttaa agttattttt atagtaacag cgattcttat
    17881 tgtagtagat gccattttga tagctgtgtt accatttcca ccagctaata atgttattga
    17941 taataaaggc aaaacagtta aatcagagaa gatgaaattt acaccaacaa gtatagctct
    18001 tgtttgtatt ggatttacat gtacatctac atttgtatta tggttaaatt gtaatcagga
    18061 attgggaaaa ttatatggga tggctgaccc tacaaaaatt caatctttct actcaatggg
    18121 agtaatatgt gcagtattaa taacttcttt acttattaaa aaatatatta aaccaataag
    18181 aatattagtt atatatccta taatagcttt acttatgcta ttagttgtat attttgttca
    18241 aactccaact atttgtatgc tagggggatt tgtaataggt tattcagcag caggaggtgt
    18301 tcttcaatta acaacatcaa ctgcaaatga aatgtttcca actaataaag gaaaaataac
    18361 gtctatagtt atgattgcat ctagtatagc aaactatgtt attttaaata tagcaggtat
    18421 tatcacaaaa tcaggtggag ttaatggacc aaaatatgtt gtattattta atgtggcaat
    18481 aacatttgtt ggaattttac ttgcattgtt tgtaaacatg agatatgaaa aagaaaaagt
    18541 gtatgattat gatgtttaat attagtataa tatatttata gagaaatcca aatttaggat
    18601 gggtttctat taaaaataat taaaattaat aaggatatta tttatagtta taagataggg
    18661 tatttacata attaataata aggatattac tagaatttca atttctagta atattttttt
    18721 gcgtataaat gtaaacttgg cgaaataagt agtataatca atataaatta catcatgtaa
    18781 aggaggataa tttggtggag aatgttttta agcgattaca ggaatttgat ggttatgatg
    18841 gatacaaaga atcatttgaa atgaattacc tatgtatata tgaaaatata cctttaagag
    18901 aacaagtaga gcttgcaaat aatctaatag atggaatttt aaatatgtat aaaagtgaat
    18961 ctaatgaaat ttatttattg gaggatagta attctaagtc tttaatttgt tattttgaaa
    19021 tttttatgaa aaagataaat actttggtaa aagaaatgat tattgatgag aaatggttat
    19081 ataaattaac taaagaatta atatataaga gtaaaaaagt tgagtatgta aaactaggat
    19141 tagttttaag tgagaaatat ctagatgtag aaaacttaag agaagttgta gatacatttt
    19201 ctaaatctgg agaatacgta ttttatttga gtaatgctat taaaaaaatt gaattttaca
    19261 atacatattt atttaattta tctaaaaaag ctacaggttc aataaaagta tttgctattg
    19321 ttaatatgga aaatttagat tctaaaataa attcctattt aattgaatat ggttataaag
    19381 atacgaagta ccaacgatta ttgatgaatt atattatttc aattgtagac ttgaatgagt
    19441 atcttgaaaa acgagattta gatagagaaa agataaacaa tttatcactt cttatatgta
    19501 actacttgct aagtgtagaa tttaaataca taggaaataa attagaatta gtgaatcgat
    19561 ttttacctat tgtagtaaat tatgggacta attttgaaag tttatattcg atttttctaa
    19621 tagctataaa cgttttaaaa gatgaaaata tagaatgtaa taaggttgaa tttgaaaaag
    19681 aaataaatga tatcttgctt agtgaaaaat ggaaaagtat atattttgag gcattaaaag
    19741 atgctagtgg aaaaacagaa gatatgataa aaatgtcaga aatttataat gtaaacttat
    19801 cttttgatga cttattacca tatttaaata gagacattag agattttgag gtatattggc
    19861 atatatctaa aaaaggaacg acaagttcta gattaaaatt attggatttt tttgaaaaga
    19921 catttaaagt agatgattta attggaaaaa tgaaagatat agaaaaagat aaattgactc
    19981 aagaatatta tgatgatatg ttatttttta ttgtgcttaa aggaagtaaa tcactatatc
    20041 ctgaaggaaa gaatatatct ttaaaaggaa tatttggaaa tataaatgaa gtaagaaaag
    20101 aatctataaa tattttaaaa agatatagag agaaattatc tcttgaagaa ttaaaagttg
    20161 ttaaggaagc atatgaaaaa gaaaaaaata tcatattgaa ggatgaatta agaagagtat
    20221 tatatgaaag taacaactta aaaaaagaat ttgtaaatat tgaaaaaata aaagtagatg
    20281 aacatggtaa ggatatctat ttaacttcaa taactgttgc tggttcaagg tttagaaata
    20341 gagaatatct tgaaaaagaa ttggagaaga gtaagatata ctatctaatt agagagaaag
    20401 ataatctata tgatgaaaaa gctattaaaa tagttggtga aactggatat gtaataggct
    20461 atgttccaag aaaagaaaat tatattttga gcaatttatt agatggagga aaactattgt
    20521 attgtagagt aactgaatat aatttatatg aagattgtat ttacgcaaat gtgtacttga
    20581 gctataaaga tgtaattgaa acggttgaaa actctttaaa gatggtttta gataagagta
    20641 gaataaaact tataaactaa gacgtctata tactgcttaa atgatgtaat cctgattagt
    20701 taattatttt ttctggaatt atggtgtatt ttatgagcaa tggtaatgaa taggaaataa
    20761 aaaaacaatt gttttgtata tatgatgtgt ataaatatat ttatatattc atatttacaa
    20821 aataattgaa atttatgtta ttttatgatt ttaaatttag atggaatttt aacgtctgat
    20881 ttatctttta ttttagaagc ttgttcctta actttattta ataattcaga ttcatctaca
    20941 actaatactt ttctttcctt catcaaccat ttaccatcac aaatagtaga atctacattt
    21001 tcactagtca tagaataaac tatatttcca attggattat gcattggtaa acaatggatt
    21061 gtatctggat ttaaaataat catatcggct ttttttccta cttcaagact accaatttct
    21121 ttttctaata aagcacattt tgctccattt atagtagcca tttctaagac ttcttcagct
    21181 ggcactactg ttgggtttaa agttctacct ttatgtatta atgatgtaag atacatatcc
    21241 ctcataaggt ccattctatt atttgaagga gctccatcag taccaattga aacagatatt
    21301 cctttttcta acatttcagg aattgatgca aatcctagaa caactttcat agctgaacct
    21361 gggtcatgag aaacttttac atcatgtaat ctaaataagt caacttcctt atgagtaagc
    21421 caaactgtgt gagcggctaa aagatttggt cctaatacac ccagtttatc aagatattca
    21481 actgttccaa ctccattgtt ttgttttaca aatgaaattt catcagctat ttcagcaata
    21541 tgcatatgta tacctgtatt gtatttatca gctaactctt tagttctaac aagtaattct
    21601 tcagttgtat taaaaatagt tcttaatgca aaccatattt taattctctc attagatgtg
    21661 ttattaaact tgtggaataa gtctaattga gtgttgattt cctcatcagt agttttttgc
    21721 catgcctcag gaagaccatc tcctgtatcc ataactgatt tagctaaaca agctctaagt
    21781 ccagttttat caacagcttc aaccatagca tctacatatt gaccaccaga ttctaaaaat
    21841 gtagtgacac cagactttat caattcaaca caacatgcag tagatgaaat caatgaatct
    21901 tcataattga agctactttc gtatggccaa attctttctc taagccaagt taaaagtaca
    21961 acatcatctg caagaccacg tcctaattgt tgagataagt gaacgtgtgt attgactaac
    22021 cctggcatta gtatttttcc tttagcatca tatatctctg catctttatc tacaatacta
    22081 atatcaaact taccaacctc ttttataata ttattttcaa taagtatgct tccgttttca
    22141 tatacctctc tatctgcatt catagtaatt agatatgcat tttttataag taattgtgac
    22201 ataaacacca ctccttttct atgtattttt atatctatgt attatgataa taaattttct
    22261 atacaaagtt aatagcaaaa tcaatttaca tataaagtga ttttgctatt tataaattta
    22321 aaataaataa gattttattc tatataattt aaaatattga cctagaacta tttaaaatat
    22381 taacttagaa ctaagtttac aactgcaagt aaacctataa tccaaagtgt aatactgatt
    22441 ttatcagttt ctttagctac cacatgcatt attatatatg aaataaatcc aaagcataaa
    22501 ccaatactta tactataagt taaaggcatc aataagactg taacaaaagc aggtactgct
    22561 attttactat cagcaaaatc aatctgtttt atgctttcaa acatgaacac accaaccatt
    22621 acaagtgcag gagctgcagc gtaagtagga actataccaa gtaatggtgt aaatataagt
    22681 gtagctaaga ataatgctgc tgttactatt gaagcaagtc ctgttcttgc acctgctgca
    22741 ataccagaag cagactctcc aaatgttgta acagtactag ttcctaagaa tgagcctatt
    22801 aaagtagaag aaacatctgc atacaacatt cttcctaaat cttttatttc accattctca
    22861 tcttcaagac ccatttgttt acaacaagta ataagaaatg ctaatgaatc aaacatgtct
    22921 ataaacatga aagagaatat aggtccaatt aatgagaatt tcaatgcacc tacaatatct
    22981 aatttaaaag caactggtgc tatactagga ggtgttgaga ttattgctgt tggcaactcc
    23041 acaaatccaa atataacaga tattattgtt gcaactacta tacttatcaa tattccacct
    23101 ttaacttttt tatattctag tattgccatt aagataagag caaaaagagc tattaaaact
    23161 gttggtgtaa aatctgcaag tgaaactata gtatctggat tagctattat aacacccata
    23221 ttttttaaac caacaaaagc aaggaaaaga cctatacctg ctgaagatgc tactgccaat
    23281 tctctaggaa ttgcgtctgc aattgtcttt cgaagacctg ttactgcgag tgtaaagaag
    23341 acacatccag atagaaaaac taccccaaga cctgtttgcc atgggattcc tgcccctata
    23401 accaaagagt atgtgaaaaa tgcatttaat cccataccag gagctagagc aaatggtgca
    23461 tttcctaaaa tcgcaaatat aagtgtacca atggctgtag ctagtatggt aactgttata
    23521 agggcggctt tatccattcc agcctcagat aatattgctg gatttacgaa aactatgtat
    23581 gccattgtta agaatgtagt aactccacct attacctctg ttttaaggct agagccacgt
    23641 tcgctgaatt taaacatttt gtctaaaaag cttaatgatg aattatttcc acctggttgt
    23701 acattgttag tgtttggtac catttttacc tccaaaaaac tttaagatat aaacaaaaaa
    23761 atatatattc atatagatag aatagaacat atattcaagg ttgacattct attcatagaa
    23821 aacccattta aggtgagttt gtagaaacta ttagaccgta ttactaatat tatatgaaca
    23881 ttttctattt gtttttctgt tgtattatat cgtaatattg tattatttac aataaatata
    23941 ataaaattat tcgttttttt gtcgatttta taaaaaatta aggttattta ttggcaaaaa
    24001 ttactgtttt aaataattga atatgtatga gtataatgtc aattattcta acttgtttta
    24061 tactattaat ggaagtttat tataaatgag tttgtgatat aattataaaa gtactgaata
    24121 cacggatatt tcgtaaa
//
LOCUS       DAMKOJ010000055        23107 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000055 DAMKOJ010000000
VERSION     DAMKOJ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23107
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.057"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(183..935)
                     /locus_tag="PC592_002424"
                     /pseudo
     CDS             complement(183..935)
                     /locus_tag="PC592_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
     gene            complement(1223..3610)
                     /locus_tag="PC592_002425"
     CDS             complement(1223..3610)
                     /locus_tag="PC592_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF4056382.1"
                     /translation="MINTTKIAKNNLKQNKSKSILIIITIILSTLMLSSIGIYIVNAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFVKGKLPTKENEIVLDSGALKALGYKNKDLGERIKISYNDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRNMSQEDFNIYVKFNDKSNLSI
                     EQIKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGISIPIGIILGYVLANIIIK
                     SFMNIDAKSSQLPVILLVAVISFISVVLSLLKPMKVASKVSIVDAVRYSGNKISNKNK
                     RKGYKNINLNRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKNNLNILQMDNPLSKDFFNQIKNIEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLSKNLIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTKEG
                     KYQEVKDSIKKIAKSNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAISYTSGMMIGSILFGGILGYIAV
                     MVLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            complement(3603..4286)
                     /locus_tag="PC592_002426"
     CDS             complement(3603..4286)
                     /locus_tag="PC592_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056383.1"
                     /translation="MKILYTENLSKHYGKGESLVKALDNVNLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDETFIKELLKSLGLENKRDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGK
                     VLKVGDKND"
     gene            complement(4403..5713)
                     /locus_tag="PC592_002427"
     CDS             complement(4403..5713)
                     /locus_tag="PC592_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4056384.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSILSILIVTIIFLLFEYSR
                     LYKLYEHQIKNTQNIAGILIEKYPNDEVDIVKSIYNSNYSKVPIGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKNLSKIYFIVDKMAQE
                     NYLKDTTVSEETGYLVEYNEYFKEGTFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILDAVKSVTPKAKNKSITLNLNEFDSRIVPHDKKWTEESI
                     FNVLDNAVKYTQINGEINISVEETANYFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            complement(5707..6414)
                     /locus_tag="PC592_002428"
     CDS             complement(5707..6414)
                     /locus_tag="PC592_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056385.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFSIEEAKSIFAKE
                     EICLIISDIGLPDGSGFDFCEEVRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIVRADNKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSAPKYIK
                     TVRGVGYIWGERSIKKC"
     gene            complement(6720..8561)
                     /locus_tag="PC592_002429"
     CDS             complement(6720..8561)
                     /locus_tag="PC592_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDF4056386.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLDRFEEITIFHTNDIHGRY
                     AEGDEHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMGKGKNAVELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGRKVFDSNDIKEINGVKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVSELKEKGADVIVAICHIGTNTLSKPN
                     SIDIANKVQGIDLIIDGHSHTKFENGKQVGDTLIVSTGQYLENIGEVKLTLDTDDVGN
                     IKIENKSARLIGKEEALKYKLDSSVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITIRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKIYPEKSSAFLQVGGISYYFNPKQKEGERITSIQKEGKPLDLD
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVTEYIEYKREISKNVDGRIGIK
                     SKDELISENQESDLILSENKESINDNEENLSNNIKSSDSDKNKILDKTRTRESSNLGI
                     SKREAREKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKNKKSK"
     gene            complement(8774..9658)
                     /locus_tag="PC592_002430"
     CDS             complement(8774..9658)
                     /locus_tag="PC592_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HDF4056387.1"
                     /translation="MKVLKKITILSLIILTLVGCSNGEDKKVVEGSKKIQNSKKNEQP
                     IIVHKDANILKDRYEPPKGFKRVNVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWVQGY
                     RISVNDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            9866..10783
                     /locus_tag="PC592_002431"
     CDS             9866..10783
                     /locus_tag="PC592_002431"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDF4056388.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILVDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPIGIVDCIRSMR
                     NLVEYIPYTLKIIENPQGSFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKKYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKNSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDTP
                     SIYLENATNVFENTILGEDRLSLHLNFDE"
     gene            complement(10912..12246)
                     /locus_tag="PC592_002432"
     CDS             complement(10912..12246)
                     /locus_tag="PC592_002432"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDF4056389.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFDDADELLARTPEKLREAGIDLNIFREVIEVDSESKKIKVKNVKTGEIYED
                     YYDKLMIATGARSIMPPIKNINLKNISTLKSLYDGEYLKKLLSNDENRRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEITDVLEEEINRHNVNLHLDEVVVELY
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSSTNIKMLKNGAIIVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITERKAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVVLGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            12586..13974
                     /locus_tag="PC592_002433"
     CDS             12586..13974
                     /locus_tag="PC592_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF4056390.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKENNLGTLTFKSLGMLLATTAIAAIVGIVVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLVFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     INKEVFSKKNIS"
     gene            complement(14055..15263)
                     /locus_tag="PC592_002434"
     CDS             complement(14055..15263)
                     /locus_tag="PC592_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056391.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNICYSGKDMIQEIKNSVAE
                     KSSLKDTISSIDNKVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGIIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNEAA
                     DNFLNQLKKYDVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKENYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLNLMDGQSDKYFTYLLGNRPLVKIKNIENPE
                     GLKVLFVKDSLIVPTAAFFSSVCSNIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(15279..16697)
                     /locus_tag="PC592_002435"
     CDS             complement(15279..16697)
                     /locus_tag="PC592_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF4056392.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYTFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMITSIIMNYIFGLLVDKYRESKIKVRIFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELINTQLTIPNIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRAPNLKEAYNYFKAMFGG
                     NGVIWSDYTYMFLKEYWIFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            complement(16715..17830)
                     /locus_tag="PC592_002436"
     CDS             complement(16715..17830)
                     /locus_tag="PC592_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056393.1"
                     /translation="MSLNPWNIFRRDKMKTLKVFFCSAKYFILVFIFFINASFISLAT
                     GDKILDLSFKKIETDLSSKITYEDTGVKIEIDSSKRDKERYLYIYQNIKENWSMYHNF
                     CIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEIFLEDRNIIYSDKINDGCIEVPGEF
                     EGKIYVNFNNLINEKSNVVLDSNTLSNIVSWGITFIPSDEEHNIVTIKKLSLLSQEKL
                     RFLNNIKIIGDEEVQIPILGQSISQYEVLGLGSNSKIKYSLIGKQNNVNLSQNGKLTL
                     SNKAKPGQIILQVNVDDNFKFGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     EINFMNSIITFIRILFVSLVVVCFGIYFYWRKCSKTK"
     gene            complement(17802..20108)
                     /locus_tag="PC592_002437"
     CDS             complement(17802..20108)
                     /locus_tag="PC592_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF4056394.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDRKKVHIYICDDGNREEMHVLAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPDVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLIFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKNKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYTAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEIEFRE
                     KSGNEMYIANMKAKIVNVVELNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRVNMNFQMDIKNIGKLRIVNFNYQYVLLTF
                     ENKNIYPKEIALEINEGIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTIIVSKPGEKKEKSIDEFEPMEYI"
     gene            complement(20113..21099)
                     /locus_tag="PC592_002438"
     CDS             complement(20113..21099)
                     /locus_tag="PC592_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HDF4056395.1"
                     /translation="MMMFFLGIVLIVFYFVIRGNSDTVKMQRGINIGNALESPKDFHW
                     DVKMSNKFFDDIKDADFDTVRIPIRFSDYTSDSDDFKIDEEFFKKIDGYINYALDKDL
                     IVVLDLHHFEEIMKEPGAHKEEFLKIWEQISNRYQKYDKKLVFELLNEPKENLSSQLL
                     NEYIEEAIKIIRKTNSKRTIIVGPYNFYQIDYLNELNIPKDSNIVVSFHYYEPNDFAF
                     QGNIYHKGFEHLRNITWEGTNEQMNYLKKRFDIVENWANKNKVKIFLGEFGITKEAPE
                     ASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGNWDRDILSALIEKR"
     gene            complement(21394..22971)
                     /locus_tag="PC592_002439"
                     /pseudo
     CDS             complement(21394..22971)
                     /locus_tag="PC592_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
BASE COUNT         7591 a         4012 c         2354 g         9150 t
ORIGIN      
        1 aactttcaca cttaggttta tttcatcctt atgttttagt ttggttagct ttaggggttt
       61 ccagcaattc aagtagtatt gaataggttc tatcctatct ctacatatag gtttccctat
      121 atgctgacta atttagctac taactcatga ctaaagtcac aagtgtgcat agctattttt
      181 taatcaagcc ccattatgtc acttattggc attgtgtaag ggaagtattt tttttcataa
      241 tagtcttccc atatatttaa attacaataa aaacctatta catcagtttt tctatttttt
      301 atacaatttt ttgcatcttg acttattcca actatagtaa gacctgctgg tgcagaaata
      361 gctttttgcg aaccgcctaa tattatgtct attttagatt catctacact taatctttct
      421 cctaccatac ctgctacaga atcaactaca gttaatattc catattcctt aagtaatgga
      481 catattttgc ttacatcatt taatacacca gttggagtat cacaatgcac tactgttgca
      541 tatttaaagt tactatcctt atctaaaaat gctttcaatt catcaatatc tatactttta
      601 gtatattcac ttgaaaaaag cacatactcc ccaccataca ttgttacaaa atctttaaaa
      661 ccttctccat atataccatt atcaattaca agtactctat ctcccttttc tgtaagtgat
      721 gcacatgctg cttcaagtcc taatatccct tcaccactca atatgtaaac atcgtttttt
      781 gtgccaacta tattgccaaa cttctcgcat gcctttttat aaaattcaac aaaatcaata
      841 tctatatctg gatttgttgt tttttctgct cttgctaatc ttacattttc cctagtttca
      901 gttggtcctg gtgcataatt aatcttctca ttcatatata tcagctccta tttattttct
      961 atacgattat tatacaaaat tttcatttta tatggtacaa ttttatactt ttttagaatt
     1021 gtaccaatac attttctgac ataaataata taaatctatt atatatatta tttattgcac
     1081 aataaaatac agagcaaaca tcagtttaaa ttgtttgctc tgtaactata ctttaaccta
     1141 tttaattatg aatctattta accatctttt ttatatggtt tttgctagtt aaactaacca
     1201 taaatacata aatatttata ttttattcac tgtatcttac tctatcaata agagattctt
     1261 tattaaaact tcgtcctatc aaataagttg ttataaattg agctataaga atacatacaa
     1321 tcatcaacaa gattggtact attggcaaag aatacgttgc ataagataat ccagtcttct
     1381 ttagaaccat aacagcaata tatcccaata tacctccaaa taaaatactt cctatcatca
     1441 ttccagaagt gtaagatatt gcctctgagt taagcatttt caccaattgt ttattagtaa
     1501 gaccaatcgc ttgaagcatc ccaagctctt tctttctagt aactatgcta gttatcattg
     1561 tgtttacaag attcataaat ccaatcacac ctattatgcc tgttaatgta taacccatta
     1621 tttttataaa cgaaatagta gccttatttg attcaattct actatctata aaatctgtct
     1681 ctaaaaatcc attagattta gcaattttct ttatactatc ttttacttct tgatactttc
     1741 cttcttttgt atatattcct aaactacttg ttgaatcgta tttcaaggtt ctatctataa
     1801 aatcctttcc tataccaaaa cttggaactc ccatagctat tgcttgaact ttaaattctt
     1861 tttttatctt tttatctcca tcatataaag ttaatcttat tttatctcct gcttttactc
     1921 ccatttcttt tgctgtatca acatgagtaa ttactatttc atctccagtt tgcaatcttt
     1981 caagatttat ttttccatct attagattct tgcttaatga ttttacatca ttttcgttta
     2041 tactttgtaa aaggtcatat ttaaattcaa catcatagtc ctccatacca atttttacac
     2101 ttcttgcaga ctctattctt ttaattcctt ctatgttctt tatttgatta aaaaaatctt
     2161 tacttagagg attatccatt tgtaaaatat tcaaattatt tttaggattt ttatcactgt
     2221 tcatttcata accagataat ctaacttcta tatcataagg aaagtgttct cttgccatct
     2281 tctcagcatc aaaactttct aaagcagtcg atactgttat aaatatagtc ccactaagta
     2341 taagtgatgc caatgtcata taagtacgtt ttttatttct ttctaaattg gcatgtgata
     2401 atctatttaa atttatattt ttataacctt ttctcttatt tttattgctt attttatttc
     2461 cagaatatct tactgcatca acaatagata cttttgatgc cactttcatt ggttttaaaa
     2521 gcgataaaac aacagatata aaacttatta ctgcaaccaa taatataact ggtaattgtg
     2581 atgattttgc atctatgttc ataaatgatt ttattataat gtttgcaaga acataaccta
     2641 aaattattcc tattggtatt gatattcctg ctaatataaa tccttcttta aatactatat
     2701 tttttatttg ttttttagtt gcaccaattg ctctaagctt tccaaattct tgaacttttg
     2761 taactattga aatataaaat atattgtata ttactaaaat actagataat acaattacta
     2821 atcctacaaa aactccaccc ataatcgttt ccatatctgg ttttaaagca tttatataat
     2881 tttcatttac agcagtatta atagtatcca atcctatatc attagcaatt ttatctaatt
     2941 tttcttttat ttgctctatt gataaattac ttttatcatt aaattttaca taaatattaa
     3001 aatcttcttg tgacatattt ctagtatttc tcatatacga ttctgatata atagcataat
     3061 aatatttacc tgcttcagat atttcgctag tttttaagat tccacttata atgaactctt
     3121 tttcaatttt tttatcattt ttgtagtcat tataagatat ttttatcctt tcacctaagt
     3181 ctttattttt ataaccaagt gcttttaaag ctccactatc taacacaatt tcattctctt
     3241 ttgttggtaa ttttcctttg acaaattcaa aactatttaa tttcaaagca tcttcattca
     3301 tatatgccag agaaatattt gaatcatctt ccagtttttc aacacctact ccattcattt
     3361 caccagttaa ttcaacatct gcatgattac tcaatatatc agcttgtttt tcatccacat
     3421 ttgctaatat accttgataa ttacctgaat actttatagt attttctttt tgatatgctc
     3481 ctgcattaac aatataaatt ccaatagaag aaagcattaa ggtagaaagt attatagtga
     3541 ttattattag aatacttttt gatttatttt gctttagatt attttttgct attttagtag
     3601 tattaatcat ttttgtcacc aacctttaat accttgccat cttctatgaa tataactcta
     3661 tcagccattt gggctatact gtcatcatga gttatcataa ctagagtttg actatacttc
     3721 ttagacatag attttaatat actcataacc tcatcagatg ttttagaatc taggtttcca
     3781 gttggttcat cagcaagtat tatagctggt cttgtagcta atgctcttgc tattgctact
     3841 ctttgttgtt gaccacctga taatgtattt ggtaaaacgt cgcgtttatt ttcaagccct
     3901 aatgatttta aaagttcttt tataaaggtc tcatctactt ctctaccatc tagaccaatt
     3961 ggtaacacta cattttccca tacattaaga gatggaatta aattatagct ttgaaatata
     4021 aaccctattt ttcttcttct aaacacagca agttcttctt cttttaatgt aaatatattt
     4081 ttattatcta tatacacctt cccagatgta ggtatatcaa gacctccaat catatgcaaa
     4141 agtgtacttt ttccagaacc tgattttcct attattgcaa caaattcacc ttcatttatt
     4201 tctaagttaa cattatccaa agcttttact aagctttctc cttttccata atgctttgat
     4261 aaattttcag tatatagtat tttcataaaa ttatcctctc attctaagtt atattacccc
     4321 atattttatt aatttcttat ttctggagtt gtttatactt atataataaa tgtagaggct
     4381 tacattttcc tttcatttaa tattacatag ttgtaagaaa caaagagaac ttgctcccta
     4441 tccctacttt tgaagaaact ataatatttc caccttgttc ttccaaaatt ttcctactca
     4501 aatacaatcc taccccacta ccttctacag attcaatttc atcagcagaa cctctataaa
     4561 aacgtttaaa gatattatta aactcatttt tttcaattcc tataccatta tcctctatta
     4621 taattttaaa gtaattagca gtttcttcta cagatatatt tatttctcca tttatctgtg
     4681 tatattttac agcgttatct aatacattaa aaatactctc ttcagtccac tttttatcat
     4741 gtggtacaat tctactgtca aattcattta aatttaatgt tatgctttta ttcttagctt
     4801 taggggtgac actttttact gcatctagaa tagtattttt tatatcatta tcttcttttt
     4861 ttatgtttat catactaatt tctaaccttg atatgttcac taaagaattt attaaatttt
     4921 ctaatttatt tatagaagct ttgttggtta ataagaactc gttggcttca tcttcttcta
     4981 attcctcttc tataagtaat gtattgtata attttaagga tgctaaagga gtttttaatt
     5041 gatgtgaaat atctgttact aatgatttta cactttcttt ttctttttcc aacttaataa
     5101 actttatctt taaacttcta ttaagctcat atagacagtt atttatctta ctaaatgtac
     5161 cttctttaaa atactcatta tattctacta gataaccagt ctcttctgat acagtagtgt
     5221 ctttcaagta gttctcttgt gccatcttat ctactataaa atagatttta ctcaaatttt
     5281 tatttatata tcttataaaa taatatatta tacctataac tactataaac atcattaaaa
     5341 aaataaaaaa tgattcctta aaaaaagatt ttaagtataa gctaaaattt ttatcatttg
     5401 acattttatt ttccaatcca tagccaaatt tcttaaatgc cttttctcca ataggcacct
     5461 tactataatt agaattataa atagacttta ctatatctac ttcatcatta gggtattttt
     5521 caatcaatat tccagcgata ttttgagtat tttttatttg atgttcatac agtttatata
     5581 atctactata ttcaaaaagt aaaaatataa tggttactat tagtatagat aaaatagaat
     5641 atacaataac tcttctcatt atataatcat ctttcacact taaaccatct ttgaggttca
     5701 tattttttaa cattttttta tactcctttc tccccatata tatccaaccc ctcttactgt
     5761 ttttatgtac ttaggtgcag atggattttt ttcaaccttt tgtctaagtc ttcttatatt
     5821 tactgcaatc gtattatcat ctacaaaatt accactacta tcccacaaag attctaacag
     5881 ttgctcttta gtcaatgtct gcatagaatt ttccatcaaa tattttaaca atttagtctc
     5941 tgttttactt aaaattatct cttcttcctt attatctgct cttacaatca atttattttc
     6001 tatatagtaa aagaataaat catcacaaac caataaagta taatttttta ctgtatttac
     6061 ccttttcata agcgcattca cttttgatat taataccatc aaactaaaag gctttgtgat
     6121 ataatcatct gcacctaaat catatcctgt gacaatatct acctcttcat caagagctgt
     6181 caacattatt atgtaaacat cacttttctt tctaacctcc tcacaaaagt caaaaccact
     6241 accatcaggc agacctatat cagaaataat taagcatatc tcttcttttg cgaaaataga
     6301 ttttgcttct tctatactaa atgcactaaa aacattgtat ccttcttttt ttaatttaaa
     6361 actaattcct ctatttaaag atttgtcatc ttctaaaagt aatatattat tcatccacat
     6421 gtcctccatt atcatacgta ctagctaaat tatatcatac tagtaaaacc gtttttttat
     6481 caatttataa atatatcaga ggttgttaat atgatttcat ttacttgaat aaaaactaaa
     6541 aatactcata gtaccgtact atttagtgta attatttttc ataaaataca actttaatta
     6601 aaagtaatcc tgttaaagca taaaaacaaa ggaaattagt atttatataa ctaatttcct
     6661 ttgctgttta ctattatcta aaattaaatt actatctact aacttttgct cattaacttt
     6721 tacttggact ttttattttt taactctttt tgattaaaat tcaataagca tattaatgta
     6781 cttgaaacta taaatataat tatactattt gaaaaaccta aatctcctgt tttaggagat
     6841 ttttctctag cttctctttt agatattcct agattagaac tttctctagt ccttgtttta
     6901 tctaagattt tatttttatc actatcagaa ctttttatat tattagatag attctcttca
     6961 ttatcattga tactttcttt attttcactt aatatcaaat cactttcttg attctcactt
     7021 attaactcat ctttagattt aataccaatt cttccatcta cattttttga tatttctctt
     7081 ttgtactcta tatattcagt aactgcactc tctaagtttc caaattcctt taagattggc
     7141 tcttttgaaa aacaaggaaa ttcatctcca cctgaagcta tataatcatt cgttgcaact
     7201 acatactttt tatctaaatc taatggcttt ccttcttttt gaatacttgt tatcctttca
     7261 ccttcttttt gtttaggatt aaagtaatat gaaattcctc ctacttgtaa aaaagccgaa
     7321 cttttttctg gataaatttt tactccatgc tccaatacat ctttaatctg tgctcctgta
     7381 agttctttgg taactattgt attgctaaaa gggaatacat ctacaatatc tcttattgtt
     7441 atattgcctt tttctatcgt atctctaata ttccctccat taaacaaaga aatatcagcc
     7501 ttagttttat ctagtaaaat gtcacttatt aaattaccta aattagtttc ttttgtcctt
     7561 acattttcat atgaaccatc tagagtattt gtagttacac ctataacttt atctaatatt
     7621 ttttcttgtt gctcttttat ttcgtcaacc tttttactta cactggagtc aagcttatac
     7681 tttaatgctt cttcttttcc aatcaatcta gctgatttat tttctatttt tatatttcct
     7741 acatcatcag tatccaaggt tagttttacc tcgccaatat tttctaaata ttgccctgta
     7801 cttacaatca atgtatcacc aacttgttta ccattttcaa acttagtgtg gctgtgccca
     7861 tcaataatca aatcaattcc ttgaacctta tttgctatat ctatactatt tggcttactt
     7921 aaagtgtttg taccaatatg acatattgca actattacat ctgcaccttt ttcttttaat
     7981 tcacttactt gctctgttgc actttctata gggtttttaa actctaaccc ctccacattt
     8041 ttaaatccag ttttgctctt tgtttcctgg gttgagagtc caaaaaatcc tatttttact
     8101 ccatttattt cttttatatc attactatca aaaacttttc tcccattttc aaaaatattt
     8161 gatgataaaa attttaaagt attctctcct aaattagcac ttttagataa ctcaaacagt
     8221 ctatcttttc cataattaaa gtcatgattt ccaggagtaa tatagtcata tccagcacat
     8281 ttaatcaatt ccactgcatt tttcccttta cccatattta ctattggaag cccatgcaaa
     8341 caatctcctg catctactaa aattgagttt ggagtttctt ttttcaatgt agctagattc
     8401 cctatttgta tatgctcatc accttcagca tatctcccat gtatatcatt agtgtgaaaa
     8461 atagttattt cttcaaatct atctagccca taagaaataa aactctgact tgttgtaatt
     8521 agaattataa ttaccaaaat taaatatctt ctaatcttca atataaatta gcctcctcaa
     8581 attagtttta gctttaatgt aaaatataaa ttttacatta aactttttag ataaatatta
     8641 aactatagta aaattaatta gtataatttt taatatttat ctatcaattt aattttgtcc
     8701 atatccaatt agttttaatc taattacatt ttttcacatc tatatttttc ttttattata
     8761 taaaattatt attttaaaat cttttcaact ggtctctttt aaaagtccat tgaggtattg
     8821 tcaaatcacc ttcaaaatct aaactatacc aaggactcaa atttggattt ttacgattga
     8881 taagaagttg agtttgttgt gcaggcatat agctttgggc tatcataaat accttttctc
     8941 cagtcttctc attttctgcc atatccataa ttatacttgc atgtcctgga cttccaccaa
     9001 ctataaatac atctcctatt ttcatatctt caacttttac aggctccaat tctttttcaa
     9061 gagataacgt tcctgaatag gcaaacacta tatccataaa ctttctgaag ctctcataag
     9121 atgttgaata ttcagttgct ttataccagc ttgaaccact atcgtttact gaaattctat
     9181 atccttgtac ccattttgaa tacttcgcct taaaaccatc aacaaaatca aaacttattt
     9241 catcatatag tttattctga tacaagtatt ctgctctcat aagcataatt gcgtctgcac
     9301 attgatgtaa atctctatta ccaatatcaa catcaaatac actatcataa ataccttttg
     9361 attccttagt tcttccatca tagtacttta ctttctctcc ataatttttt agcttagtat
     9421 tcctaagaaa tgattcaaaa cttccttttt ctacattgac tcttttaaat ccttttggtg
     9481 gctcatacct gtctttcaat atatttgcat ctttatgtac tattataggc tgttcatttt
     9541 ttttagaatt ttgaattttc ttagaacctt caaccacttt tttatcttct ccgttactac
     9601 aaccaactaa agttaatata atcaatgaca aaatggtaat tttctttaat actttcatta
     9661 atttctcctc ctttaaattc tcctaaatat aatttttact ttttgctaca caaattttta
     9721 tacattgtta tataaaaact ctatttgaca atatttcttg actcaagtgc acatttattg
     9781 ttatatttaa tgttaaaata attataatag gatatcataa taaaaacaaa caacagattt
     9841 gtgttaattt tagaaagggg aaaaaatgat agatttaact ttacttggat gtggtggaaa
     9901 tgtacctatg ccaaacagat ttctatcctc tgtatttata aactataaag gtagaaaaat
     9961 attggttgac tgtggtgaag gtactcaggt atctatgaag ctaaaaaaat gtggctttaa
    10021 agatatagac ttaatctgta taacccattt acatggtgac catatatttg gacttttagg
    10081 gcttttatca acaattggaa atagtggtcg tacaagtgat ttaactatag ttggtccaat
    10141 tggaatagta gattgtatac gttctatgag aaatttagta gaatatatac catatacttt
    10201 aaaaattata gaaaatcctc aaggcagttt ttctttagat aataaagttt taaggaattt
    10261 agaaatttca acaatcagtt tagaacactc tatagagtgc ttaggataca gttttaattt
    10321 tagaagaaac cctaaatttg atatagataa ggcaactaaa aatgaagttc ctaaaatatt
    10381 atggaataag ctccaagaag gccaaaatat agttttagat tcaaaaaaat atactccaga
    10441 tatggtctta ggggaattga gaaaaggagt taagataagt cttacaaccg atacaagacc
    10501 tatagaatca ataccagatt tcataaaaaa tagtgattta tttatatgtg aagccatgta
    10561 tggtgatgac ttagatatat caaaagctgt tagaaacaaa catatgactt ttagagaagc
    10621 tgctaatctt gcaaaactag gaaatgtcaa acaactttta ctgactcatt ttagcccttc
    10681 tttagataca cctagtatat atttagaaaa tgctactaat gtttttgaaa atactattct
    10741 tggagaagat agattaagct tgcatttaaa ttttgatgaa taatttaata taatacttgc
    10801 ttttaaatat ttgaattaaa aatttaggaa tgaattttac catgacaaaa atattttagg
    10861 taaattcatt cctttaattg cttttcaatt atattagcta taatctaaac attatttaga
    10921 tacattccca gctacattta aaacatccca ggttcttgca aatggtggag cataacataa
    10981 atctaacatt ccaagttgac ttgtagtcat tttcccaaat atagcagctg ccaatacatt
    11041 tgctctttga acagcatcct taaaaccagc cacttgtcca cctaaaacaa cttttgtatc
    11101 tgcatcataa ataagcttta catatatttt atttcttcct ggataataat gagtttgatt
    11161 atagtcagaa ataaatttag atttaacatt tatacctaaa tctttagctt ttctttctgt
    11221 aattccagtt gatgctgctt ccatatccat aatttttata caacttgaag atagtgagcc
    11281 ttgataagat acttctcgtc ctgctagatt ttctcctact atcctaccca atttattagc
    11341 tccagtagct aaaggcacat atacattttc attgcttact atattcttta tagttgcaca
    11401 gtctccagca gagtatatat cctccacaga ggttctccca tattcatcaa ctattatagc
    11461 tccatttttt agcattttta tattagtact tgacaagaac tcggtgtttg gtctaacacc
    11521 agtagcaatt attactacat ctgtatctat ttctcctttg tttgttataa ctttttctac
    11581 tttatcttct ccataaagtt ctacaaccac ttcatccaag tgcaaattaa cattatgcct
    11641 atttatttct tcttctaata catccgtaat ttccttatca aatacttgtg gcaatattct
    11701 atcttctaac tgaatcacat ccacatcttt tcctaacttc ttacatgcct caactgcttc
    11761 taatcctata aaaccagctc ctattattgt tactcttcta ttttcatcat tacttaaaag
    11821 tttttttaga tattctccat catataaact ttttaatgta gaaatattct ttaaatttat
    11881 gttttttata ggaggcataa tacttcttgc tccagttgct atcatcaatt tatcatagta
    11941 atcttcatat atttcacctg tttttacgtt ttttactttt attttcttag attcactatc
    12001 gacttcaata acttctctaa atatatttaa atcaattcca gcttctctaa gtttctcagg
    12061 tgttcttgct aataattcat cagcatcatc aaaaaatcca ccaacaaagt atggtaaccc
    12121 acaagcacca aaagatacta tttcggtttt ttcataaaca acaacttcat actcaggttt
    12181 tattcttttt aattttgctg cagcactcat accagctgca acaccaccaa ttattattac
    12241 tctcatttta tctctccttt gatgtctagt taatttcttc acttatttta agctttttag
    12301 tttatatata ttctatgtaa acatttttta taataatttt tagttattta tttaacacat
    12361 ttttatttga aatcaaatct tatcaaagct attttttatt ttgttagcac aattcaaatt
    12421 ccttaaatag ttattatacc ctatttttct atatttaatc acatttttca aaattatttt
    12481 tttactctat ttaagcaaat tattgatata atattgacat ttttttaata tattgatatt
    12541 atttaaactt agaaaaattt atttttaaat aaaggagaaa aaacattgga aagttcattt
    12601 ttatcacaat ttcttatgat tacagatttt aaaacgattt ttttcataat cttacttcta
    12661 ggtacattct ttattgttag acaatttgaa aagaaaaaaa tcaaattttc attgagaaca
    12721 atatatgcta cagtactagg acttatattg ggaattataa tccaagcttt tgctggtttt
    12781 cctaatgata ccactcaagt cacttggcta caagaagtaa gcaagtggta tagtctattt
    12841 ggttctggat ttatggactt attaaaaatg ttagtagtac ctttagtttt cttatcaatt
    12901 ataaaagtaa ttataaatat gaaagagaac aatcttggaa ctctgacttt taaatcttta
    12961 ggtatgcttc ttgctaccac tgctatagct gcaattgttg gaattgtcgt tgcaaatata
    13021 atgaagttag gtgtaggagc taatatgcct actctagttg aaaatcaaga acttaaagaa
    13081 ataaactctc ttgtggatac tttaagagga ttactaccat ctaatcctgt aatggctatg
    13141 gcaaatggaa atattgtagc tacaataata tttgctacat ttatagctac ctcaataaaa
    13201 agattgagca aaaaacattt tgaaacaata aaaccattta tagattttat agaagcctct
    13261 tacaagataa ttgtaagtgt gtctatgact gttattaaat ttatgcctta tgctgtggtt
    13321 gctctacttg caaatacaat aacttcacaa ggtattagct caatagtatc tgttttacag
    13381 tttatattag ctctttatat atcagttgca atattattta tcatacattt agtttttata
    13441 actttaaatg gtctaaatcc tattacttat ataaaaaatt caactgaagc tttacttcta
    13501 gcatttactt cacgttctag tttaggaaca ttacctgtaa cgatagaaag cctcgtacaa
    13561 aaccatgggg ttgatgaagg tgtatcaagc tttacagcaa gtttaggtgc aaatatgggt
    13621 atgaatggtt gtgcgggtat atatcctgct ttaatggctg taacacttgc taatatggct
    13681 ggtgtaaaca tggatatgag tttttatgtt atgttgctaa ttgttataac aattagttcg
    13741 tttggtatag ctggtcttcc aggaactgct acaatggccg tttcagttgt tatctctgga
    13801 gttggtcttg gttcttattt tccattagtt ggtggtatac ttgcaataga ccctatatta
    13861 gatatgggac gtactatgat aaatgttaat ggtgctatgg tatcatcaat tactgtagga
    13921 aaatcacttg gaaaaataaa taaagaagtt tttagtaaga aaaatatttc ttaaaataag
    13981 tatgaaaata aatggctaac cttcaaccaa ttagccattt attttttatt ttgttagaaa
    14041 atttttttag gaatttactc acaaaatgga aaaaattctt ttgtaagatt ttggggatat
    14101 acagatataa aaacaaagtc atagtcatga gactttgcat attctagtat atctccatca
    14161 tagtatctag ggtctatcat atctatattt gaacaaacag aggaaaagaa tgctgctgta
    14221 ggtacaatta aagaatcttt aacaaataac acttttaatc cctctggatt ttctatattt
    14281 tttattttaa ctaatggtct attccccaac aaatatgtaa aatacttatc tgattgaccg
    14341 tccattaaat taaggtctgc attaaaagga tacgataata tcagactctc ttcaaatctt
    14401 ccttttagtt caaatttttg agatttagaa tctgtataat aagtataatt ggtcttaaat
    14461 ttaggataaa ttaatgtaaa atcatctata ccaccatata aaataccagt ctttcttccc
    14521 atagaaccaa gaaatgactt gggatataca attgaattat aattttcttt atctctataa
    14581 taatgatttt catctagatt catattgtat tttttattaa gttgctcaac taattctcca
    14641 aatgcccaaa aagaagtttc tactttccag tgatggtctg ttttaaaaaa taaatcatct
    14701 ttgggaatac cactctttaa gatattttct ctaaaatcaa tatagtccac atcatacttt
    14761 tttagttgat ttaaaaaatt atctgctgcc tcattgctat aagaataagg tatccctttt
    14821 ggaaattttg tcactccttt tatatactta tctggagtca ttaaataaac caatttagtg
    14881 ttttgttttt ccatttcatc agaaaacttt cttactctat ctgctatgat gccaactgga
    14941 tttggagctt tagcaaaata tgtataatgc atttttccag aagtatcttt tacaacacta
    15001 aattttgaaa actcattttt acccattaat ttttgtaaat atccataagt ttcaatgaat
    15061 gtatttttat atattacttt atcatttact ttattatcaa tagatgatat tgtatctttt
    15121 aaactacttt tttcagctac tgaatttttt atttcctgta tcatatcttt tccagaataa
    15181 caaatattaa agatagagaa agcgaataaa ataattaaaa acataattgc agttattaat
    15241 cttactttaa aaaatctatt catacttttc cctcccaact aaaaattaaa ataaataaat
    15301 ggattatagc ttccagttac taaatatgtt acagaaataa agaacaataa aatagctgat
    15361 ataggataaa atacattaaa tatcatacta tatttagctt gttcaacaac aaacttattg
    15421 attttcttcg ctataggtac actaaaaata aaagcaaata taaagaaaat ccagtattct
    15481 tttaaaaaca tatatgtata atcactccat atcactccat tgcctccaaa catggcttta
    15541 aaataattat atgcttcttt taagttaggt gctctaaaca atacccatcc aaaattaact
    15601 actaataacg cataaatatg ttttataaaa ttatgatttt caatcttttc aaacattata
    15661 aatcgctcta taattagaaa aacaaagttt aaaatccccc aaattacaaa tgtccattct
    15721 gctccatgcc atattccagt aaataaccat actataaaca tatttctaat cataatatct
    15781 ttatttgcta ctctagagcc tccaagcgga aagtatatat aactcttaaa ccacattccc
    15841 aaagagatgt gccatcttct ccaaaactca ctaattgatt ttgatatgta tggataatta
    15901 aagttctctt caaatttaaa accaaacata agacctaatc ctatagccat atctgaatag
    15961 gcagaaaaat caaagaatat ttgcagagta taggctattg aaccaagcca tgcaagtgat
    16021 gcagctattt ctccttgact attcatagtg taaatatagt ctgctactat agccatgtta
    16081 tttgaaatta acactttttt acctagacct gttataaacc tacaagtacc aatagaaaat
    16141 ttattccaag tttcttttct attgagaatt tgttctgcta cactctcata tctaactata
    16201 ggacctgcta ttaattgtgg gaaaaatgct atatataatc ctacataaaa aggattcttt
    16261 tggacttctc catgtctacg atatacatct ataacataag acattccttg aaatgtaaaa
    16321 aatgaaattc ctataggtaa aacaatatta ggtatagtta attgagtatt aataagttca
    16381 ctaatatttc ttagtgcaaa agccagatat ttaaatataa ataaaacacc tatattgtat
    16441 gcacacatca aaactaaaaa aattcttact tttattttac tttccctata cttatctact
    16501 aataaaccaa atatatagtt cattattata gaagttatca taataacaac aaatttcggc
    16561 tctccccaag cataaaaaaa taaactaaca gcaagcaata tcatgttctg tatcgttcgg
    16621 ttaaatctaa atgtataata taaaactaaa gttataggta aaaaataaaa taaaaaaatt
    16681 aaacttgaaa ataacataat tcaacctcct ctctttactt agtttttgaa cattttctcc
    16741 aatagaaata tattccaaaa cataccacta ctagagatac aaataaaatt cgaataaatg
    16801 ttatgatact attcataaag tttatttctt tcatatcttg tactgttggt gattgttcag
    16861 gagataccag tgtatatgga acaccatctt tatctttttt attaatactc caagattcag
    16921 ttaatgttat tttctttcca aatttaaaat tatcatcaac attaacttgt aaaataattt
    16981 gtccaggttt ggctttatta cttaatgtca atttgccgtt ttgagagaga tttacattat
    17041 tttgttttcc tataagagaa tacttaattt tagaattact tccaagacct agtacttcat
    17101 actgacttat gctttgaccc aatattggta tttgtacttc ttcatcacca attattttaa
    17161 tattatttaa aaatcttaat ttctcttgag acaataaaga taactttttt atagtaacaa
    17221 tattatgttc ctcatcagat ggaataaatg taattcccca actaacaata tttgaaagcg
    17281 tatttgagtc tagcacaaca ttacttttct catttataag gttattaaag ttcacataaa
    17341 ttttgccttc aaattcacct ggtacttcta tacatccatc gtttatttta tctgaatata
    17401 ttatatttct atcttccaaa aatatttcac taccttcttt taatctaaat tcaagcatat
    17461 tcttactttg tatacttaaa tttattctct gggaactttt atttttattt tgaatctcaa
    17521 tacaaaaatt atggtacata ctccaatttt cttttatatt ttggtaaata tataaataac
    17581 gttccttatc tcttttagag ctgtctattt ctatttttac acctgtatct tcatatgtaa
    17641 ttttagaact taagtcagtc tctatcttct taaaggataa atctaaaatt ttatcacctg
    17701 ttgctaaact tataaaacta gcatttataa aaaaaataaa cactaaaata aaatattttg
    17761 cagaacaaaa aaacactttt aaagtcttca ttttatctct cctaaatata ttccatgggt
    17821 tcaaactcat ctatactttt ttccttcttt tcaccaggtt ttgaaacgat aattgtctta
    17881 ttttgtaata tccaatccat catttcatct cttaaaaaga aattttgcat tatgctatca
    17941 atattattca ctttatataa gatacctctt tcatcaattt taccctcaca taaatcgcat
    18001 tctaatacaa taccttcatt aatttccagt gctatttctt taggataaat atttttattc
    18061 tcaaaagtta ataatacata ttgataatta aagtttacta ttcttaattt acctatattt
    18121 tttatgtcca tctgaaaatt catattgacc cttggacttc ttcgtgataa tgttctagtt
    18181 ttttcaatac gtttttttac attaatttgc aaatcatcaa aaaaacctag ttgattagat
    18241 attgtcattg gtaaagtagg tattctatca tgaacaatac acatccaatt atctatttca
    18301 ctatcttcaa tatgtgtaat gtaagctgca tatttccact ttgaatttag ttccacaaca
    18361 ttaacaattt ttgctttcat attggctata tacatttcat ttcccgactt ttctctaaac
    18421 tctatctcaa actcttcttc tggagaaata tattctggat tttctagcaa aaatgcaaac
    18481 ccattttctg atatatcaat cgtttttgaa gaaagaacat aagaattttg ctttaattta
    18541 aaatcaattt cagcagtata acgctcagac tttcttaact gttgtcttcc tgatataaat
    18601 agcgtagcca taacaaggtt aaaaaggttt ccaatcaacc aaaataatac aactgaatat
    18661 gtcattgaac tcattttaaa tattgctaca aacattttta aaattcctat aatagataag
    18721 accatataaa taaaatacgg tattccttgt aaaaacttat acattctatt ttcttctaac
    18781 ttattcttat ttgttactga aaatttattt ttagatattg caaatgtttc aagtattact
    18841 gctggcatta aagactgaaa cattatagtt tcatatatat tagtccatct agtattcctt
    18901 atattttgag aaaatatttt aagagataaa ctacttaaaa tatacattgg caaccaaaat
    18961 atcaatactt gaagtaatgt acattttact acaatcacat taaatacaga aaacaaaata
    19021 ggtgccatta tatatacaaa gcgttttata cttgcatacc aataagtaat tgaagaaata
    19081 taacttattt tctgccaaaa tcctaaacct ctcctaaaca aaatgtttag gcgtctacca
    19141 gtttgtatac atccacgtgc ccatctttca cgttgcttaa taagactttt taaatctgta
    19201 ggagataaac ctgaggcatg tacatctgga atagcataac atctataccc cttactttga
    19261 attaagatac ctgttgcaaa atcttctgta atagaataag tataaaatcc atcaacttct
    19321 tcgagtgctt cccttgaaat aactgtatta ctaccaccat aaattacaga atttgtccta
    19381 tttctagcca attgaatgtc tctgtaaaaa taatcttgct catttggaat ccttccctca
    19441 gagtgcagat taaattggaa caagtctgga ttataaaaac tctgtggagt ttgcacaaaa
    19501 ccaacctttt catactcttc tttttctcca tcttttttag cttgctcatt ttttaaaaaa
    19561 tatggtactg tagcaattaa aaagtcatgc attggtatca tatctgcatc aaatgtagca
    19621 atcaaaggtg agtttgtatg ttgcattgca ttatttaaat ttccagcttt tgcaccttct
    19681 ctttctgttc tagttatata atttacaccc attttttctg ctagaacatg catttcctca
    19741 cgatttccat cgtcacatat gtatatatgc acctttttcc tatctggata ctgcatatga
    19801 atacatccat ttacagtttt tctcaccaag tcaacagatt cattatatgt tgcaatgaat
    19861 acatctacat gtggataaag ttcttcactt ataattggtt tttcaggata ctcaatattt
    19921 gacataccat aataatgcac aaacatttcc atcataccca ttatctctac aaaaagaagt
    19981 attatcgcac agattaaggc aaacatccct tcttctttag gtactgtata aaaaattctc
    20041 cacaatatat atacgatatt agtaataata gttaaagtta taagtatctt ttttgaattt
    20101 ttcttcataa aatcacctct tttctattaa cgcgcttaat atatctctat cccaattccc
    20161 ttcaatttga ttgtatatac caaatccaga agcaagctcc caataagccc atgaaaagtt
    20221 tcgtttttca gcttcttctc ttacagcttt tatccaagct cttcttgaag cttctggtgc
    20281 ttcttttgtt attccaaatt cacccaaaaa tatttttacc ttatttttat ttgcccaatt
    20341 ttctacaata tcaaaccttt tttttaaata attcatttgt tcatttgttc cttcccaagt
    20401 aatatttctt aagtgctcaa atcccttatg atagatattt ccttgaaatg caaaatcatt
    20461 tggttcataa tagtgaaagg aaactactat attagaatct ttaggaatat ttaattcatt
    20521 caaataatca atttgataga aattatatgg tcccactata atagttcttt tagagttagt
    20581 ttttctaatt atctttattg cttcttcaat gtattcattt agcaattgtg aggataaatt
    20641 ttctttaggt tcatttaata attcaaatac caatttttta tcatattttt gatacctatt
    20701 agatatctgt tcccatattt ttaaaaactc ttctttatga gctcctggtt ctttcataat
    20761 ttcttcaaaa tgatgcaaat ctaatacaac tattaaatct ttatctaatg cataatttat
    20821 atatccatca atctttttaa aaaattcttc atcaatttta aaatcatcag aatctgatgt
    20881 atagtcagaa aaccttattg gtatacgtac tgtgtcaaaa tctgcatctt ttatatcgtc
    20941 aaaaaactta tttgacattt ttacatccca gtgaaaatcc tttggtgatt ctagtgcatt
    21001 acctatattt atccctcgtt gcatcttaac tgtatcacta tttcctctta ttacaaaata
    21061 aaatacaata agaactatac ctaaaaaaaa catcatcata atacctattc tttttatctt
    21121 actctccccc taacactgct atcttatata taatattatt caatccctat tataacaaat
    21181 taaattatat catgttatat acaattattg taatttacaa actttatagt gttgatagtt
    21241 ttaaaacatt aaatgcaact aaaaaacaaa aatctatctt gaaatagaaa taatcctttt
    21301 tcattattaa agtgatgaaa ctatatttga cttcacacaa aaagagtgtc tcatgaacta
    21361 aaaagttcat tttgagacac tccattatat tttttataat cgttctaaca actctagcac
    21421 atatttttta actttatcat atccacaatt atcaagtgaa tatcccagtt ctatgtcacc
    21481 aaaaccttta atttcagcat tttctttttt atttaataat tcttgcataa gctcaacttc
    21541 tatatactct cttccctttt ctttttctaa cattgtaaat aactcaaagt cctgtattcc
    21601 aaaccttaaa ttctccactc taacacttct aactggcttt aaatcttttc caggataaac
    21661 aaagaacata tctccagctt tccaaatagg aaatttgtag cttgaatctt tccaagggtc
    21721 ttctgtccat aaattatagt cccatcttaa aaaaccatca agaccaaaat agtaagtata
    21781 ccatcctatt attctatttt ctacaaaagg agaacttata aaactatttg gtttctctgg
    21841 aaaacaacat acaaaccaag tcaatattcc accattgtta ttgatttttt tcttaagatt
    21901 ttctatatct ttataatttt ggatagtaag ttttaaattt attgacatat catcaatttc
    21961 atctttagct ctatctaaaa aattttggtc atgggttgct gatttatatt taacttgatg
    22021 agttcctaca gtagaattta taaattctat acactctttg actacttctg gattatttgg
    22081 ttcgtcagct ataatcctta ctctgtccca taatccacac tctattaaat gatttaacac
    22141 taatcctata tattctttta aatcatctgt attatttata aatttgaata ctttatcact
    22201 ttcatcaaaa tatcttactc ttatagggtc cttataacct tctacaggat ttccaaactc
    22261 accagcacac caattaccta atagaccaaa taaatctatc tcctgagcca ttttatgctt
    22321 atcagctatg cttatatact tatccatact ctcaaagtta cacttaatct ttccatccaa
    22381 tccttttgat acgcttacca tgttatattc atataagttt gatggatttt tataaacttt
    22441 ataacaactt tgtcctgccc atggataatc tgaaactata actgttgcaa ctttttctcc
    22501 taaagatgct aattctttta aatagttatc aattatttca aaatgtatat cagaccataa
    22561 ctcaacttta tacattctag ctaagcaact tggatgttgc cataaatcta aaaagaactt
    22621 actttcattt aaaggcttta acacgacatt ttttactttt acaggaacat caattgtaca
    22681 aaatttttct tcatcttcat atccaaagct tttaaatata tcaataccta tattaaggtt
    22741 attttcttta aaatcttctg gtacttgacc ttcaatccaa aatgtttgag gcaaatattg
    22801 ctctactaac acatctttat cccttaaaat agcatcattt acaaatgctt ttgtatcatc
    22861 ttgaacatac cccaatatat ttatactaaa attattttct aagctattag gtacatttaa
    22921 tgctaatctt actctatttc ccagaccctt ccatgatata gtactgcttt tctgaacctc
    22981 ccatgactaa agtcacaggg ttcctgcttc atagaatttt gcatactaaa atatgtctta
    23041 ctaattctcc acaggctatc cccatagttc ctacggttct tatataagtt atttattttg
    23101 aattgtt
//
LOCUS       DAMKOJ010000056        22654 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000056 DAMKOJ010000000
VERSION     DAMKOJ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.058"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            153..1658
                     /locus_tag="PC592_002440"
     CDS             153..1658
                     /locus_tag="PC592_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDF4056396.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHEHKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAAV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            2054..3151
                     /gene="dinB"
                     /locus_tag="PC592_002441"
     CDS             2054..3151
                     /gene="dinB"
                     /locus_tag="PC592_002441"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF4056397.1"
                     /translation="MELHRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLKK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLNIDEEETRNILDELCEEVCH
                     RLKSSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRRGIDNLLRNVEMNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            3414..4550
                     /locus_tag="PC592_002442"
     CDS             3414..4550
                     /locus_tag="PC592_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056398.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSGEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDVDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            4543..6090
                     /locus_tag="PC592_002443"
     CDS             4543..6090
                     /locus_tag="PC592_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF4056399.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKLVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVNKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMRHTPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVLNMLSGKINEETMRELNYQVDELGKSPEDVAHSF
                     LVKEGLV"
     gene            6368..7234
                     /locus_tag="PC592_002444"
     CDS             6368..7234
                     /locus_tag="PC592_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF4056400.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVSR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRVGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLFGVKLGFPVIIESIVPIIISVFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEKSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            7375..8517
                     /locus_tag="PC592_002445"
     CDS             7375..8517
                     /locus_tag="PC592_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF4056401.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLGGGTIPKYNKELSF
                     LSKDDESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHAIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANTVKV"
     gene            8901..10139
                     /locus_tag="PC592_002446"
     CDS             8901..10139
                     /locus_tag="PC592_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056402.1"
                     /translation="MDGDILMSKILKYKNEIFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLLTFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGAGIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNIYNIFLSLLLVTII
                     ISNINGFIEILNIGIKSYPV"
     gene            10168..11055
                     /locus_tag="PC592_002447"
     CDS             10168..11055
                     /locus_tag="PC592_002447"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HDF4056403.1"
                     /translation="MKQTNTNIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLLLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSAYILF
                     VVLSLISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRGDAVEHRKILEDYDVENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNESNPTDIILTDN
                     ALKINVILWIITCLIILIF"
     gene            11089..11718
                     /locus_tag="PC592_002448"
     CDS             11089..11718
                     /locus_tag="PC592_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDF4056404.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMVPLKKAKEAIFYPIVDFSEEDLKSFFDDCIMKKINESIKKVIYKNKEGY
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKNGEVIEQINS"
     gene            11723..12187
                     /locus_tag="PC592_002449"
     CDS             11723..12187
                     /locus_tag="PC592_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HDF4056405.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHILQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            12437..13804
                     /locus_tag="PC592_002450"
     CDS             12437..13804
                     /locus_tag="PC592_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4056406.1"
                     /translation="MENSSTNLGNESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIIMACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWIFGASESTIGYSMDYLNIYLMGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIVLPVLGLGISPFIMQSTESLVLISLNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCLTYSTILWL
                     LLMIFPTFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIEE"
     gene            14004..15278
                     /locus_tag="PC592_002451"
     CDS             14004..15278
                     /locus_tag="PC592_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDF4056407.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDIRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RVKAAKEELFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            15396..16115
                     /locus_tag="PC592_002452"
     CDS             15396..16115
                     /locus_tag="PC592_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF4056408.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASNKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYHGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGVRVILGTDSHICYSIGKFENAEKVLKSVDF
                     PDELVINYHEDEIIGFFDINF"
     gene            16136..16582
                     /locus_tag="PC592_002453"
     CDS             16136..16582
                     /locus_tag="PC592_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056409.1"
                     /translation="MSKNKFIYMNYYDNGYFKRGMAIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLSALSLEDEKKLLNIIDEKMKKFKA"
     misc_binding    16730..16976
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17100..18842
                     /gene="leuA"
                     /locus_tag="PC592_002454"
     CDS             17100..18842
                     /gene="leuA"
                     /locus_tag="PC592_002454"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDF4056410.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESVKGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMSTPNI
                     YADQIEWFCENVSCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIREIYEDCTKLIVHDRHPYVGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKIESDRIGEELSSEAIFNLFRKEYIDVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARVSYMGNEQRIVGVGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEVK
                     NGDDYDAENLSQTC"
     gene            18799..20076
                     /gene="leuC"
                     /locus_tag="PC592_002455"
     CDS             18799..20076
                     /gene="leuC"
                     /locus_tag="PC592_002455"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDF4056411.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDIVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGKIGVDGALYKSMEFCGEGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTIEYINSHKCTTITKDVNVYQADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILASGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            20091..20582
                     /gene="leuD"
                     /locus_tag="PC592_002456"
     CDS             20091..20582
                     /gene="leuD"
                     /locus_tag="PC592_002456"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDF4056412.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIEEGDKIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            20589..21659
                     /gene="leuB"
                     /locus_tag="PC592_002457"
     CDS             20589..21659
                     /gene="leuB"
                     /locus_tag="PC592_002457"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDF4056413.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVEVCRKNEAVLLGAVGGPKWDKCKGDTRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVDKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     ETYNENEIRRIGKRAFEIARNRSKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVREPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLRDDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEYAVQSILNKGYRTID
                     IHNGVGTVVGTKEMGELIVNEI"
     gene            22022..22537
                     /locus_tag="PC592_002458"
     CDS             22022..22537
                     /locus_tag="PC592_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDF4056414.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDVAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
BASE COUNT         8733 a         2363 c         4114 g         7444 t
ORIGIN      
        1 accataaaac tatcttgaaa aaaattaatc ttaattgtat aatattactt tgagtgaaaa
       61 agtattaaca tttttttata agatgtttta ctaaaaaaat atatataaat atactgttat
      121 caacaagaaa tttaatttag tgaggtgtta agatgaaagt aggatttgac cacaaaaaat
      181 atttagaaga gcagtctaaa tatatcttag aaagagtaaa taattttgac aagctttatt
      241 tagagtttgg aggaaaattg atgggagacc ttcatgcaaa aagagtgctt ccaggatttg
      301 atgaaaatgc aaagataaaa gtattacaac atatgaaaga aaaagttgaa gttgtaattt
      361 gtgtctatgc aggagatata gaaagaaaca aaataagagg agactttggt atcacttatg
      421 atatggaagt tttaagatta atagatgatt taagaggtta tgaactagat gtaaatagtg
      481 tagtaattac tagatttgaa ggacaaccag ctacaactgt atttataaat aaattagaac
      541 gtagaggaat taaagtttat aagcactatc caacaaaggg atatccgtca gatgttgaga
      601 ctatagttag tgatgaggga tatggagcaa atgaatatat agaaactaca aaaccaatag
      661 tagtagttac agcaccagga cctaatagtg gaaaacttgg tacttgtcta agtcagttgt
      721 atcatgaaca taaaagaggt aatgtagttg gatattctaa gtttgagaca ttcccagttt
      781 ggaatgtgcc tgtaaaacat cctttgaata tagcttatga agcagctaca gttgatttaa
      841 aagatgtgaa tatgatagat tcattccatc ttgaaacgta tggtgaaatg tcagtaaact
      901 acaatagaga tttagaatta tttccagtac ttaaaaaaat aatagaaaag ataactggaa
      961 aagaatcaat tttccaatct ccaactgata tgggtgttaa tagagttggc tttggaataa
     1021 tagatgatga agtaataaga aaagcttcta tagaagaaat aataagaaga tactttaaaa
     1081 ctgcttgtga gtataaaaaa ggacaagttg ataaaggtgc ttatgacaga atgaaaatga
     1141 ttatggaaga acttaactta aagccagaag atagaaatgt tgtattacct gctagaaatt
     1201 acagtaataa attgaaagaa agtgctgaca agaatgacac ttgtcctgta gttgcattag
     1261 aattagaaga tggtacaata ttaactggta agggttctga tttaatgaat ggaacagcag
     1321 cagcagtatt aaatgcaata aaacatttag ctaatatatc tgatgatatg cacttaatat
     1381 cacctgtaat attagagcct atcataaact taaaaacaaa aactttagct agtagaaatg
     1441 tttcacttag ttgtcaagag gtgttaactg cacttagtat ttgtgctgta actaatccaa
     1501 ctgcacaatt tgctatggaa aagttagcct tattaaaagg gtgtcaagct cattctacta
     1561 ctatattaaa tagggatgat gaacaaacat ttagaaagct tggtatagat gtaacttgtg
     1621 acccagagta tccttcacaa aatctttact atagttaaag ttaaaattat ataaaaaaat
     1681 atgggctgtt ttaaagtaat agtttgagca gtccattaca attataataa aatcagtagg
     1741 ctgtcttgta taagacagtc ttttgttttt aaaacatccc atttaaatta aatatatata
     1801 ctgttatcca taaggaattt taaatttagt tccttggaat acctattgta aagcttttat
     1861 atagtttttg caagtgtttt taaggatttt ttataaatta tattgaagtt aatggattat
     1921 aggtggtttt atttattgaa aatatgaata tataaataaa ataatgaaaa aataccaaaa
     1981 agaaacataa gtttggtata attaaaaagt aatataaata aaattaatct atttatactt
     2041 taaaggtgat atgatggaac ttcatagaaa aataattcat atagatatgg atgcttttta
     2101 tgcatctata gaacaaagag ataataaaaa attaaaagga agacctgtta ttgtcggtgg
     2161 aaatccacaa agcagaggtg tggttgcaac atgttcttat gaagctagaa agtttggtat
     2221 ccattcagct atgccatcag ctgtagctta caataggtgt ccatatgcag tttttgtaag
     2281 acctagattt gatgtttata agagtgtgtc agagcaaata agagatatat tttatagata
     2341 cacagattta gttgaaccat tatctttaga tgaagcttac ttagatgtaa caaaaaataa
     2401 aaaaaatatt gattcatcaa ttgagatagc aaagcaaata aaaaaagata tatttagaga
     2461 agttggtctc acttcttcag ctggtgtatc atacaataag tttcttgcta agattgcatc
     2521 agacttaaaa aagccaaatg gattaactgt aataaccgaa gaaaatgccc aggacttttt
     2581 agacaaatta cctgtgaata aattttttgg tgttggaaaa gttacttcaa atactcttaa
     2641 aaatttaggt ataaaaactg gctatgattt aaggtgttta aatttatttg agcttgaaaa
     2701 tatatttaaa aaaagaggtt atgaattata taaatttgct agaggaatag acgatagacc
     2761 agtagaacca aatagggtta gaaaatctgt tggggcagag actacattaa gtcataattt
     2821 gaatattgat gaagaagaaa cacgcaacat tcttgatgaa ctttgtgaag aggtgtgcca
     2881 tagattaaaa agttctgaga agtttggaaa aacattaaca ttaaaaatta aatatgagga
     2941 ctttacaaag ataactagaa gccttagttt agaacattat attgacgaat acaatgatat
     3001 aagaagaggt atagataatt tattgagaaa tgttgagatg aatggaaaac aaattaggct
     3061 attgggagtg acaatatcaa atttaagtga taaaaaagaa acttataaag atattacctt
     3121 atttgaatac atggatagta tccaaatgtg agttttgttt aaataaaata atactagttt
     3181 taatattata taattgaagc tagtattatt ttatgaatat ttttatattt tttgcttttc
     3241 gatattatat attacacact atatataaat actttatatt tgtgtcaata ttcagacaaa
     3301 tattgctcta aaagtcgtac tttgtttaca taaataaaat agtatgatat aattataaaa
     3361 acaacttata atattgaaga aggttgcttg ttcgaaaaag gggatgataa attatgatag
     3421 agataagaaa tgtaacaaaa aaaataggaa ataatgttat attagatgat atctctctag
     3481 ttgtagaaac aggtacattg gtagttttga ttggttcaag tggttgtggg aagactacta
     3541 ccttgaagct tataaacaaa ttaataaaac ctacatctgg tgagatatat attaatggca
     3601 aaccaatttc tcaggaaaat gaaatagaac ttagaagaaa aataggatat gttatacaga
     3661 acacaggcct attccctcat cttacaataa aagaaaatat agagctaatt ccacgcctaa
     3721 aaaaggaaaa atccgttgaa gaaattgaaa aaagaacatt gcaactactt gagatggtag
     3781 gacttgatag tggtgaattt ttaaataagt atccttcaga gcttagtggt ggacagcaac
     3841 aaagaatcgg tgttgcaaga gctattgcca ctgatgctga aataatattg atggatgagc
     3901 cttttagtgc tttagaccca ataacgagaa catctttaca agaacaatta ttttctcttc
     3961 aagatgaatt gaaaaaaact ataatatttg taactcatga tatggatgag gctttaaaga
     4021 tagctgataa aatttgtatt atgaaggatg gaagaatagc acaatatgat actcccgaaa
     4081 atatacttag aaaacctgca aacgactttg taaaagattt tatcggagaa gatagagttt
     4141 gggataatcc agaatatata aaagcaagag atattatgat aaaaaatcct attgctgtta
     4201 attccactag aactgtaact caagggatag aaattatgag aacgagtaag gttgacagct
     4261 tactaattat agatagagca aaaacattaa aaggtattgt tactgtaaaa gatatgaaag
     4321 atgttgatga taagtcaata ttacttgctg atattatgtc aagtgagcct ttgcatgtaa
     4381 atgaaggtga taatttagta gaaatactaa atgtaatgaa tcgtaattcg gttggatata
     4441 ttccagttat ttctgatgaa aataagctgg tagggcttat tactagaagt agtttacttt
     4501 ctgttttaag tgaacaattc ctagaaatgg aggtgagtgt acttggctaa tttttttaac
     4561 tttatactat tacaaaaaga taagattata gagcttttaa tacaacacat gagtctaact
     4621 gttacatcta ttttaatagc tataatagtt ggtgttcctc ttggaataat tatttcaaga
     4681 atctcatctc ttagaaaact tgtacttgga tttgtaaact tagtccaagc agttccatct
     4741 atggcacttt tgggtcttct tgtacctata cttggtatag gaagtaaacc agctatattt
     4801 atggtagtag tttattcatt acttccaatt gtaaaaaata cgtatatagg tataacaagt
     4861 attgacccag tagtattgga atcagctaag ggtattggtc ttacaagaaa tcagacatta
     4921 tttaaaatac aattcccttt agcacttcct ataataatgg gtggagttag aatatctgca
     4981 gttacagctg ttggtttgat gactcttgca gcatttatag gtgctggtgg tttaggatat
     5041 ttagtatttt caggagttca aactgtaaat aataatatga ttttagcagg ggcaattcca
     5101 tcatgtataa ttgcactgtt agttgattat ttatttagca aaattgaggt tgcagttact
     5161 ccaaaaggat taaatccaaa agcacctaag aaaaattata tagcacttaa agtaatatct
     5221 gtagtagttg ttgtttcaat gttgttcgtt gtttttagtt ctagtttttc aagtaaaaaa
     5281 gatacaataa ctattggttc taaagattat acagaacaac ttatacttgg taatgtttat
     5341 gctgaattag tagaaaaaaa tacgaatctt aaagttaata agaatttaaa tctaggtggt
     5401 tcatctgttg catttaatgc aattaaatct ggtgagttag acatgtatgt tgattataca
     5461 ggtacacttt tggtaaatgt aatgagacat actccaatta aagatgctga tgaagcatat
     5521 aatgttgtaa aagatactat ggaaaaagaa aatcagttaa ctttacttga ccctcttgga
     5581 tttaataata cttacacatt agccatgatg cctgaaactg ctgaaaagta tggaataaat
     5641 actatttcag atttgactaa atatggtaaa gaatttacat tctcaccaac tttggagttt
     5701 gaaaatagag aggatggtct tgtaggactt tctagagatt atggtttaaa attcaaagat
     5761 gtaaaagcaa tgaatggaag tttaagatat acagctttag ataataatga atctcaggtt
     5821 atagatgcat ttttaactga tggtcttatt aaaaagttta atcttaagat attagaggac
     5881 gataaaaact tctttgtacc atattatgca gctccattag tgagagaaga tactttgaag
     5941 aaatatcctg aattagaaaa agttttaaat atgctttcag gaaaaataaa tgaagaaact
     6001 atgagagaac ttaactatca agtggatgaa cttggtaaat caccagaaga tgttgctcat
     6061 tcattcttag ttaaagaagg tttagtataa aaaattaatt gtttatcaaa actctaatgg
     6121 agtgtctcaa aatgaacttt ttagttcatg aggcactctt tttttgtatg aaataaaata
     6181 tattttatta ttttaataat aaaaaagaag tttattttta tttataatta agtttcaaat
     6241 tgaatgaaca agtacaacca attttgaata taaatatagt aaatgtgctt atatacgatt
     6301 ttattatctg gttgattgat attgatagat agctttttta ttgaatcgaa gggaggggga
     6361 atttgttatg gataactata agaaagtgaa gcaagtatta tggataattt tatttgctaa
     6421 ttttgcagta gcattattaa aaatcattat tggtaatcaa attaaaagtt acagtatgac
     6481 agcagacgga tttcattctt tgtcggatgg agcatctaat atagtagggc ttataggtat
     6541 tttctttgca tccaaaccaa aagataaaaa tcatccttat ggacacaaaa aatttgaaat
     6601 tataaccagt ttatttataa gtggtatgtt gtttgttata gcaattaaga taattcttag
     6661 tgcagtgtca agaatagcta atccagttgt acctgctata actatagaaa gtttaattgc
     6721 tttaattatt acacttttta taaatatttt tgtatgtatg tatgaatata gagttgggac
     6781 taaactaaat agttatgttt tgatttcgga ttcattgcat acaagaagtg atatatttgt
     6841 atctctaggc gtattggtta ctttatttgg tgtcaagtta ggatttccag taataataga
     6901 atctatagtt cctattatta tttctgtatt cataatttat tcagcttatg gaatatttag
     6961 gccatctatt ggaattttgg tagatagagt ggctgtagat gaggattata taaaagaaat
     7021 tgtatttgaa tttaatgagg taagggatgt tcacaatatc agaagtagag gtagcaaaag
     7081 ttccatttat attgacatgc atgtaatggt agacccattt ataagtgtag agaaatctca
     7141 tgatttaaca cataaaattg agaaacaaat acaggaagaa attaatgaga atgctcaagt
     7201 aatagtccat attgaacctt tttatagttt ttaatttagc tataaaatgc aagttataaa
     7261 aaaatataat ttataaaaaa aatattatac cataaataat ttataaaaat tatttatggt
     7321 ataatatttt ctataaagaa attaagtctt aatatatcta aggaggaatt tacaatgaga
     7381 tacgttgaat atggaaagac ggggaaaatg gtttcagtag ttggttatgg aggattaagg
     7441 tttgatttag aaaaaagtaa tcaagaaaat gctgatttag tcaaatatgc gtatgaaaaa
     7501 ggtattaatt actttgatac agcaccaggg tattgtgatg acagaagtga agatatattt
     7561 ggactagcct ttagacaaat gataaaggaa ggtaagaccg atttttatgt atcaactaaa
     7621 gaaaaaccaa aagcatgtga tacatcagaa aaagctatag aagctgtaaa aaaatcaata
     7681 gaacgattag gcgtatctaa aataaatttt tatcatgttt ggaatattag gaagatggaa
     7741 cattatgaac tagcaatgag acctggaggt caatatgaag gattattgaa gtgtaaagaa
     7801 gaaggattga tagaccatat agtattttca tctcatcaac caggagatga ggttatagat
     7861 attctaagtg aaaataagtt tgaaggtgta actatgggaa ttaatatatt gaactttcca
     7921 tatagattaa aaggtgcaaa gtatgctgtt gataatggat atggtgttgt ggcaatgaat
     7981 ccattaggtg gtggaactat tccaaagtat aataaagagc tttcttttct atcaaaagat
     8041 gatgaaagta ctatagaatc agctttaaga ttcaacatag gaatttcaca aataagtata
     8101 tctttgatag ggtttaataa aaaacaagat atagatgatg catgtaaaat tgcagacgaa
     8161 aatagaattt attcagatga ggatatacat gctattgaga ctagactaaa taagaatatg
     8221 aacgaaatat gtacaggctg tgggtattgt aaagtatgtc caaaaggtat taatacccca
     8281 gcttatatgc ttttttacaa tgaaaaacag atgtttaaaa agagcgatga agaaatgaca
     8341 aagttagttt atggcttagg acattggaat tatacaatga atagtaaggc aaaagctaaa
     8401 gaatgtatat cttgtggaaa atgtgaggtt gaatgtactc agcatttacc tataatagat
     8461 agactaaaag agattaaaaa atgggaagaa gatggagcta atactgttaa agtgtaatta
     8521 attttatatt atatttgaaa tttgtatagt atttagtaat tctttaaaac atagttttag
     8581 tgtttaagga gacagattat aattttgtct ccttaaatta tgctttaatt tgttatagtt
     8641 taattacata agcaaaattt tatattttta tataaaattt ttcaaatatt ttacattaat
     8701 attgcttaca aattctcact ttatacaacg ctaatctatg ttatataaac aacgtttgac
     8761 tgattataac atcaataaag caaatattgt ggttgtaaat aaagagctat tcaattacaa
     8821 taaaacaagt aagaacatta tgaagagggc tattaaatat aaggaataaa ttgtaggtgt
     8881 cagcaaatcc tatataatga atggatggtg atatattgat gagtaaaata ttaaaatata
     8941 aaaacgagat atttttattt atattagttg taataactta cttaataata actaagatat
     9001 ttttttctaa gactactata ttttatgatt taaacaatac ctatgatgta ttgttagata
     9061 cagatacagg ggttttattc aatttaaatg tatttgctat aagtcaagat aatagtaagc
     9121 acatattatt ttcagcaatt atatcaattt ttgcatatcc aatataccta ttttgtactt
     9181 caatagcaaa tcctgggaca acagatttta atagtgctta tgggtttgga ctaatttgtc
     9241 tacaaataat aactagtgct atgtcaataa ctttagtttt taatcatatt aaaaaaataa
     9301 aaatgcagag actaacttta attttgctta ctatgataat gatattttct tttccacaac
     9361 tatttatgac tttaaatgta gagagattca tatatagtca attttcatta atatttttca
     9421 tagttattgc aaacaagatg aaagggaaaa attcttattt agtagaatta gcagctattc
     9481 ctctatttgg aataactatt agtaatatat atttgtattt ttttaatatg atatttgagt
     9541 ttaaattgaa aataggaaaa atgttaaaac atttacttac atttatctta atggcatata
     9601 tttgtgtggt ttcaacgaag tcttatgaga gttttatgaa ccttggaaat gtaatacagt
     9661 atgatacgaa atttataagt ggagaaccaa ttttagaaaa gattgcaatg attatagaga
     9721 gactgttgta ttcggttttt tattttcctg gagcaggtat taaaaaaggg ttatttttgc
     9781 aaaatggaga agttgctaca ataccagtaa ttcttacatt attggcttta tgtttttgtg
     9841 ttttatcagt tattgaaaat tcagaaaaaa gagttcctaa gctatgtatg ggaataatta
     9901 tattcaatct aactttacat ggtatagtag gatataatct agtcaattca agtattatgg
     9961 ctataaattt tagttttgca gttataatct tattggctta ctttacaaaa gctcttagaa
    10021 aaaatgaaaa aaatatttat aatatatttc tatcattgtt attggttact ataataatca
    10081 gtaatataaa tggatttata gaaattttaa acatagggat aaaatcatat cctgtttaaa
    10141 aaataatatt gaaagggtag taagtttatg aaacagacca atacaaatat aaggcttctt
    10201 actaaaattt cagattatat aaagttaatg agaataaagc aatatataaa gaatttcttt
    10261 gtattttcag ctataatttt ttcaaacaac atactaaata taaatttatt attaaatacg
    10321 tttattgcat ttgtgtgttt ttgcctaatg tcatcatcag tatatgcgtt gaatgatgct
    10381 atagacatgg ataaggataa aaaacatcct aaaaaatgta atagaccagt ggcaagtgga
    10441 agaataagca aaaaaagtgc ttatatacta tttgtagtat tatctttaat ttcagtctgt
    10501 ttatcaacag ttgttagttt taatctttct ataattctca gtctttattt gataaacaat
    10561 atattatatt ctcttaaact aaagaatata atactattag atgtgttttc catatctctt
    10621 ggttttatac ttagggttta tgcaggatgt gtggccataa gtgttagttt gtcaaattgg
    10681 ataattctat gtacattttt cttatctctg tacttagctc ttggaaaacg taaaaaagaa
    10741 atagaaactt taagaggtga tgcagttgaa catagaaaaa tactagaaga ttacgacgta
    10801 gaaaatctaa atcaaatgat gatagttata ttaagttcta caattgtatg ttatgcacta
    10861 tattctacaa gcaatccaga aaagcctcat atgatattta caaccatatt tgtagtttat
    10921 ggtgtactta gatataatta tataattaac actacaaatg aaagtaatcc tactgatatt
    10981 atcctaacag ataatgcttt aaaaataaac gtaatcttgt ggataattac atgtttaata
    11041 atattgattt tttagtgata tttttagtga taggatgggg atatacttat gaaaaaaagt
    11101 gtattattac ttgatgtaga ttatactgtt ataaatactg atagcatgat agattttttt
    11161 atttactctt taaaaaataa aacttttaaa actattataa agttgcccta tattattttt
    11221 attctattta tgtatttgat tagaatggta ccgttgaaga aagcaaaaga ggcaatcttt
    11281 tatccaatag tagattttag tgaagaagat ttaaaaagtt tttttgatga ttgcataatg
    11341 aaaaaaatta atgaatctat aaaaaaggtt atttacaaaa ataaagaagg ttataatgtt
    11401 ataattatga taactgcatc tccatatgca tatatgaaat attttaagta ttatggtctt
    11461 gcagatgagg ttataggcac tgagtttttt tatgaaaatt caagatataa aaatcaattc
    11521 attggagaaa actgtaaggg aattgaaaaa gtaaaaagaa taaaggctgt attaggtaag
    11581 cttggtatag agattgatta tgaaaattca tatgcatatt cagactctaa gagtgattta
    11641 ccaatgcttt cattaactaa aaatgcgttt ttagttagta aaaagaatgg tgaggttata
    11701 gagcaaataa attcataact taatgtcact tagaatagga gggaatagtt tgggatattt
    11761 acacatatta attttatcta tggttcctgt aacagaatta aggggagcca ttcctatagg
    11821 gattgcaatg ggattaaatc ctatatgggt ttatgtattt agtgtaatag gttctacatt
    11881 ggtatcgatt cccttgatat tgacatttag acatatatta caatttttaa gagggaagaa
    11941 actatttaaa gggattgctg atgtaattga taggaaaata aactcaagaa tgaagaaatt
    12001 aaaaagtgtt tcgataattg gtataatact atttgtgggt ataccactgc caactacagg
    12061 aacatggact gcatctgcta tagcttccat attaaaaatg agaataaaag atgcttttat
    12121 gggagtattt cttggcaatt tgctatcagg agttatagtt tcagctcttt ctttacatat
    12181 aatataaaac tatctaagta atatacttgg atagtttttt tatgagtaca tgtgaaaaat
    12241 ttttaagaac aaataaaaag tgagataaag tatttaaatt cagttagttc taaaatgttt
    12301 actatggcaa aagaaatata gtatagtatt acttgtaggg aaagcactct aaatttgtct
    12361 gctgataaag tgaaagtttt atagagaata aaattttagt gatatatttt aattattgga
    12421 ttgaggaggt tttaaaatgg aaaattcaag cactaaccta gggaatgaga gtgtgggtaa
    12481 attattattt aaacttgcca cacctgctat tatcgcacaa attgtaaatg ttttatacaa
    12541 catagtcgat aggattttta ttggtagaat ggaaaatgga gaagttgcta tggctggtgt
    12601 tggagtggca tttccaataa taattataat aatggcctgt agttatttaa ttggtatggg
    12661 aggaggtcca ttagctgcta taaaaatggg ggagcaaaac aatgatgagg cagagaaaat
    12721 aatgagtaac agtttttctg tactggtaat tttagcaata cttttgacta taggttttaa
    12781 gattggaaaa gagcctttac tttggatatt tggagcaagt gaatctacaa ttggatattc
    12841 aatggattat ttaaacattt atttaatggg aacagtattt gttcagattt caatgggtat
    12901 gaatactttt ataaataccc aagggtttgc tacaactgga atgatgacag ttgctatagg
    12961 cgctttgata aacataatac tcgacccgat ttttatattt ggttttaata tgggcgtaaa
    13021 aggcgctgca ttagctacta taattgcaca aggagtttct gctatttggg tgcttatgtt
    13081 tctttttgga aagaaaagca tacttaaaat aaaaaagaag tatatgatac caaaagcaag
    13141 tatcgtctta ccagtgttag gcttgggaat ctctccattt ataatgcaat ctacagaaag
    13201 tttagtactt atatccttaa atagtaaatt acaaatgtat ggaggagatt tagcagtagg
    13261 ctcaatggcc ataatgagca gtataatgca aattcttatg cttcctaata tgggggttac
    13321 acaaggagca caaccaataa taagttacaa ttatggttca ggtcaacttg atagagtaaa
    13381 aaagacattt aagttatgtc tattatcatg tcttacatac tctactattt tgtggctttt
    13441 attaatgata tttcctacat tttttgttag tatatttaat aagaatccgc agttacttag
    13501 tatgactagt tggagtataa aaatatattt tgctggtgct tttatgtttg ggattcaaat
    13561 agcttgtcaa cagacatttt tagcacttgg aaaagcaaca atatctttag ttttagctct
    13621 acttagaaag attgtacttt taataccttt aatatttata cttccaacat tctttaatga
    13681 aaaacttttt gcagtaattt tagcagagcc agttgcggat ataacagcag ctactataac
    13741 agcaatttct ttctttatat tttataaatg ttttctatca aaacctaaag caatagaaga
    13801 ataagatata caatataaat tttttatgaa aatattttat tagataaaaa ttagaatttg
    13861 tattttaatt taataagata ttttctataa tgtataaata tatgaagctg aatttatttt
    13921 aaaaattata gtaagaaaaa tgtaagtatt tgcaatatta atggtataat atttacagat
    13981 atgataatca ataagaggaa aggatgttta taatggaaaa tgatttaaca atgcaagaat
    14041 tacttgacca gcaagagcaa gtattcagca aagtgaaagt tggagaattg acaactggaa
    14101 aaataactgc agtgagaaat gatgaagtac aattaggatt agactatggg tttgatggaa
    14161 taatacctat aagtgaattg aacatagaaa aaaatcaata tatagaagat atataccata
    14221 taggtgatga aataactgct gtaataacaa aagtatctca aaaagatggg acaataactt
    14281 tatctaaatt acaacttgac aaaagaaatg attttgctga gttacaaaaa gcttatgatg
    14341 aacatagaat aataactgta aatgttgaaa agaatataga taaaggtgta tttgctaatt
    14401 acaatacata tacatttttt ataccaattt ctcaacttga tacaaaattt attacagaca
    14461 catctaaatt tgttggtctt aacttagaag tttatataaa agaattggat attagaaaaa
    14521 atagacttgt agcatctcat agagatgtat tacaagagcg tataaataaa gagagagaag
    14581 aaagaagagc tcaaattaag gcggaaaaag aagctgaaag agcaagaatt aagcaagaaa
    14641 gagaagaaga aaaagctcgt gtaaaagcag ctaaagaaga attatttaac tctcttgaag
    14701 ttggacagaa aagagatggt aaggtaacaa agataatgcc ttatggtgca tttgtggata
    14761 ttggtgggat tgaaggatta gcacatataa acaatttagc ttggacaaga gttgaaagtg
    14821 ttgaagatgt tgtttcagag ggacaagaag tagaagttta tgtgttggat gtaaataaag
    14881 aaactaaaaa aattgccttg gcattaaaag acataaataa tgacccttgg gatttaatag
    14941 caaaagaagt acagattgat gatgttgtca atgctaaagt tcttagaata atagaaaaag
    15001 gggcttttgt tcaaattaaa gaaggtgtag atgcgtattt accaatatct gaattaagtg
    15061 atactagagt ggctaaagtt actaatgttg ttaatattgg agatgaggtt aaagttaaga
    15121 ttcttgattt taaaccaaag actaaaagaa tgttggtttc aataaaagaa gcaactagag
    15181 agccagaaga ggatataaca gaatacttag aagtagagga atctttagga agtattggag
    15241 aattatttaa agataaattt aaagatttag aagtgtaaaa taattgaaaa tggggctgtt
    15301 ttaaaacgtt acactgtctg ttatgacagc tttagttttg aaatagccct ttagctattt
    15361 tcacgaattt atgtaaaaca ttaggaggaa atttaatgaa aaagtctatt atggatgtac
    15421 attgtcacac tctaataagt ggacatgcac atagtacttt caaggaaaat gtcgaagagg
    15481 cgagtaataa aaatataaaa tacttaggaa tatcagacca cggacctaat atgccaggag
    15541 ggccacatcc attttatttt tataatttgc atttgctccc acgagaagtg caaggtgtaa
    15601 agattcttag agggatagaa ggaaatataa tggattatca tggtaattta gatgttcaag
    15661 aagatatgtt gcaacatttg gattatataa tcgcaagttt gcatagacct tgtatagctt
    15721 caggtacaaa agaagaaaat acaaatgcta ttttaaaagt catggataag cctaaggtaa
    15781 aaataattgg acatccagat gacagtaggt atcctttaga ttatgaacct atagtaaaga
    15841 aagctaaaga taaaaatatc cttttagaaa taaataattc atcattaagt tcaaactctc
    15901 atagaactgg tacttgggaa aatgtaagtc atatgttgac attgtgtaaa acatatggtg
    15961 taagagtaat tcttggtact gactctcata tatgttattc tataggaaaa tttgaaaatg
    16021 cagagaaagt tttaaaatca gtagattttc cagatgaatt agtcataaat tatcatgaag
    16081 atgaaattat aggatttttt gatataaatt tttagaatat tgggagtgaa aaaatttgag
    16141 taaaaataag tttatctata tgaattatta tgacaatggt tattttaaaa gaggaatggc
    16201 tatatatatg gttttggcac ttataatttt agccacaatt tttatatatt caacgacaat
    16261 attatatatt ttatgtataa taacagcagt ttttctattt aagcaaggtc gtgatttttc
    16321 aaataaatat gagggaaaag tgtatattac tctcgataat cattcaatat taataaataa
    16381 tcaatgtata ttcagtataa aatctaaaca aagccaaaag tttaattata agataataga
    16441 aaaaatagaa gtggtaaaaa atatattaaa tatatacact gatgaatcta attataaaat
    16501 tagattaagt gcattgagtt tggaagatga aaaaaaatta ttgaatatca tagatgaaaa
    16561 gatgaaaaag tttaaggcat aatatcatac tgttttcaat agttagcatg ttttatagaa
    16621 ttgcttatca aaaataaaaa atcgagataa ttattttttg tgttgacaat atattttaat
    16681 gtgtatataa taactattaa atcaaaatat ttagaaaatt taaatgataa aaaaagtgat
    16741 gaatagaagt agtaagaacc atgaaacttt cagagagcta aagggtggtg tgatttagca
    16801 gttgatagtt ctgaacttgt ctaggagctg ttttctaaga tttaaatctt agaataatcg
    16861 gagtaattcc acgttatagg aaatatagtc attataatta ttgtattggc tattactaag
    16921 ggagcttttt agaaagctaa atagagtggt accgcgagca aaacctcgtc tctaatttta
    16981 ttagagatga ggttattttt attctaatga taaaattgac atttattctt atgaattgtg
    17041 cagtattgcg tcgatataag gtatactgaa tacaaaaaaa caaaaaaggg ggaaataata
    17101 tgaagtgtgg aaagtataaa aaatatgata aaatgcaaat agtaaatcgt aaatggccag
    17161 ataatgaaat atttaaggct ccaatttggt gcagtgttga tttaagagat ggaaatcagt
    17221 cactaccaac acctatgagt gtaaatgaaa aagtcagaat gttcaaaatg cttattgata
    17281 caggctttaa agaaatagag gtaggatttc catcagcatc aaatacagag tatacatttt
    17341 taagaaaatt aatagatgag aatatgattc cagatgatgt aactatacaa gtccttacac
    17401 aatccagggc tcatcttata gaaaagacat ttgaatcagt aaagggatgt aagaaagcaa
    17461 ttatacattt atataactct acatctgttc ttcaaagaga tgtggttttt aatatgagta
    17521 aacaagaaat aatagatata gcagttgaag gggcaaaatt atttaatgaa gaagtaaaaa
    17581 aatatccaga gacagaattt acttttgaat attcaccaga gagttttaca ggaacagaga
    17641 tggattatgc acttgaaata tgtgaggcag tgatagatgt ttggaaaccg actccacaaa
    17701 aaaaagtaat aataaatctt ccatcaacag ttgaaatgtc aacaccaaac atatatgcag
    17761 accaaataga atggttttgt gaaaatgtaa gttgtagaga ttctattata ctaagtttgc
    17821 acactcacaa tgatagagga acttgtacag ctgcaagtga acttggatta ttagctggtg
    17881 cagataggct tgaaggaacg ctatttggaa atggtgaaag aactgggaat atggatatag
    17941 taaatgttgg acttaatctt tacacacaag gaatagaccc agaactagat tttagtaata
    18001 tagataagat aagagagata tatgaggact gtacaaaact tatagtacat gatagacatc
    18061 catatgtagg taatcttgta cattgtgcct tttcaggttc acaccaagat gctattagaa
    18121 aaggcatgat agcaatgaaa aacagagata atgattactg ggaagttccg tatttaccaa
    18181 tagaccctca tgatattgga agagagtaca aagaaattat cagaataaat agccaatctg
    18241 gaaaaggagg agctgtttat ataatggaaa cagattatgg atttatgata cctaagaata
    18301 tgcattctga ttttggaaat gtagtcaaaa tagaatctga tagaatcggg gaagagctta
    18361 gtagtgaagc aatatttaat ttatttagga aagaatatat tgatgttgag agtccctata
    18421 aggttaagaa atataaaata aaatcaatgg atgaattaaa ctatgaaaat gatgattcta
    18481 atgatactaa catgattgag atgactgcaa gagtaagtta tatgggaaat gaacaaagga
    18541 ttgttggtgt aggaaatgga cctgtagatt catttaataa tgcactaaag caatgtggaa
    18601 tgaaagatta taaatttaga tattattggg aacatgcatt agaggaaggg tcacattcaa
    18661 gaggggtagc ttatgtagga atagagcaca ataatgaagt atattttggt gtaagtatat
    18721 cagaaaacat aaatacagca gctattaatg cacttatgaa tgcaataaat aaaagttata
    18781 ttgaggagga agtaaaaaat ggggatgact atgacgcaga aaatcttagc caaacatgct
    18841 aagttaaatg aggttaagaa aggtcagtta attgaagcag atttagacat agttttaggt
    18901 aatgatataa catcaccagt agctattaga gaatttgaaa aattaggaat tgaagatgtt
    18961 tatgataaga ctaaagtagt gatggtttta gaccatttta cacctaacaa agatataaag
    19021 agtgcagaac aatgtaaatt tacaagaagt tttgcaaagt caaaaggagt tgtaaatttt
    19081 tttgatgtag gagatatggg aatagagcat gttcttcttc ctgaaaaagg tatagtaact
    19141 gctggagatg taattatagg tgctgattct catacttgca catatggagc attaggagca
    19201 ttttctactg gtgtaggttc aactgatatg ggagcgggta tggctacagg gaaatgttgg
    19261 tttaaggttc ctggagcaat aaaatttgtt ttgaagaata aaccaaataa atggataagt
    19321 ggtaaagata taatacttca tataataggt aagataggag ttgatggtgc gctttataag
    19381 tctatggaat tttgcgggga aggagtagaa tacttatcta tggatgatag gtttactatt
    19441 tgtaacatgg caatagaagc aggagctaaa aatggaattt ttccagtaga tgataagact
    19501 atagaatata taaattcaca taagtgtaca acaataacaa aagatgtaaa tgtatatcaa
    19561 gctgatgaag atgcagtcta tgatgaagta tacgaaatag atttagctga actaaaagaa
    19621 accgtagcct ttcctcatct tcctgaaaat actagaacag tagatgaaat tgataaggat
    19681 ataaagatag accaagttgt aataggttcc tgtacaaatg gaagaatatc agaccttgaa
    19741 gtagtagctg agataatgaa aggcaaaaaa gtagcagatg gagttagagt tatgatattt
    19801 cctggaacac aaaaagtata tcttgaagct atagaaaaag gatatattac tacttttata
    19861 gaagcaggag cagcagtttc tacaccaact tgtggaccat gtctaggggg acatatggga
    19921 atacttgcat caggtgaaaa gtctatttca acaacaaata ggaatttcgt aggaagaatg
    19981 gggcatgttg attcagaggt atatcttgca agcccagctg tagcagcagc atcagctata
    20041 actggaaaaa tatcaaagcc atcagaaata atttaatgga ggtaaaattt atgattgcta
    20101 acggaagtgt ttttaaattc ggagataata tagatacgga tgtaataata ccagctagat
    20161 atttaaatat agctgattat aaagaactag caacacattg tatggaggat attgatgata
    20221 aatttatctc taaggtaaaa aagggagata ttatagttgc aactaaaaac tttggttgtg
    20281 gttcatcaag agaacatgct ccaattgtaa taaaagaaag tggagtatcc tgtgtgattg
    20341 cttctacttt tgctagaata ttttttagaa attctataaa tatagggctt cctatacttg
    20401 aatgtgaaga agctgcaaat aacatagagg aaggggataa gatagaagta gatttttcca
    20461 caggtgtgat aaaaaatata acaaaaggaa aagaatataa agcagaacca tttccagagt
    20521 ttatgcaaaa tattatatta aatgaaggct taattaactc aataaaagca aatagggggt
    20581 agtggagtat gaattgtaat atagcagtca taaaaggtga tggtgttgga ccggaaatta
    20641 tagatgaagg tataaaggtt ctaaataaaa tttgttgtaa atttaatcat agattcgatt
    20701 gtgaatatgt attagcagga gggtgtgcaa ttgatgaaac tggagaacct ctacctaata
    20761 aaactgttga agtttgtcga aaaaacgagg ctgtattact tggtgctgtt ggaggaccaa
    20821 agtgggataa atgtaaggga gatacaagac cagagtctgg tcttttaaaa ttaagagagt
    20881 cattgggttt atttgcaaac ttaagaccag ccacaatgta tgaaagtata aaagaagctt
    20941 caccacttag aacggatata gttgataaag gcattgattt tgttgttgta agagaattaa
    21001 cagggggcat ttattttgga gaacgtggaa gaaaaattat tgatggtatt gaaaatgctt
    21061 atgatgtaga aacatataac gaaaatgaaa taagaagaat tggtaagaga gcttttgaaa
    21121 tagccagaaa tagaagtaaa aaacttataa gtgtagacaa ggcaaatgtg cttgagagtt
    21181 caagactttg gagaagtata atggaagatt tagctaaaga gtttgaagat gtagagctat
    21241 cacatatgta tgttgataat gctgctatgc aagttgtaag agaacctagc caatttgatg
    21301 taatagtaac taataatata tttggagata taatatctga tgaagcatct atgattacgg
    21361 gttctatagg tatgttacca tcagcatcac ttagagacga tagttttggt atgtatgaac
    21421 caatacatgg aagtgcacct gatatagccg gaaaagatat tgtaaatcca attgcaacta
    21481 ttctatctgt aagcatgatg ttaagacata gttttaacct agaagaagaa gctaagtgta
    21541 ttgaatatgc tgtacaaagt atacttaata aaggttatag aactattgat atccataatg
    21601 gtgtgggaac tgttgtagga acaaaagaaa tgggcgagtt aatagtaaat gaaatttaga
    21661 attatagttt aatttgtata atataattta aatatataac ttggaagatt gctacaaatc
    21721 tattatagta taatttgttt tatgaggggt gtctcaaaat aaactttatt agttaatgag
    21781 gcactctttt ttatattaag tcaaatatat ttttaatatt ttaataacga aaaagaggct
    21841 tatatctatt ttgagtttct attttgataa agttattttt tagaaaataa tactttaaat
    21901 taaacttatc atattgaaat agcctatttt tattattaga agtttgcagg gattttatta
    21961 atattatata atatatttta gaattattta atattaagcg actactaatg tcggttagga
    22021 gatggatttt ttggcaaagt ataaagtttt aaagaagcaa aatagtagca aatcttgttt
    22081 agtttgtgga acacaaaatg agttaggact taaagcagat ttttatgaac ttgaaaatgg
    22141 ggagcttgta tcaatttgta atacaaagga ttggcatcaa agttatcctg gaagagttca
    22201 tggaggtatg tctgctgcaa tattagacga gactattgga agagctgtaa gtataaatga
    22261 tgaccaaata tggggagtaa cagtgtcttt ggaattgaaa tataagaaac cagtaccaac
    22321 agatgctact ataaaagttg ttggaagaat aactaaagaa aacagaaaat tatttgaagg
    22381 tacaggagaa ataattctac caaatggaga tgtagcagta acagcaactg gaaagtatat
    22441 gaaaatgcct attggacaaa ttgcagaagg tgatttttct aatgaagaat ggttctttga
    22501 agaatcgaaa gaaaaagtgg aatatattga actttgatta gataaaaatt ttatattttc
    22561 aaacataaat tttatattta taaaaaataa aattcaaaaa tacaataaaa atacaagata
    22621 aaaataaatt agttatacta aaaagattta tcgt
//
LOCUS       DAMKOJ010000057        22329 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000057 DAMKOJ010000000
VERSION     DAMKOJ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22329
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.060"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            56..172
                     /gene="rrf"
                     /locus_tag="PC592_002459"
     rRNA            56..172
                     /gene="rrf"
                     /locus_tag="PC592_002459"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            626..1696
                     /locus_tag="PC592_002460"
     CDS             626..1696
                     /locus_tag="PC592_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056415.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGKLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGNPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVITKEVLGNETIYCLSVLNSEIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDLKICKNMYSKIKGDIYEKAI"
     gene            1680..2549
                     /locus_tag="PC592_002461"
     CDS             1680..2549
                     /locus_tag="PC592_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF4056416.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2593..3453
                     /locus_tag="PC592_002462"
     CDS             2593..3453
                     /locus_tag="PC592_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF4056417.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIIQFLVMVP
                     AAYAFSKIKFKGEKVLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQVSDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3484..4788
                     /locus_tag="PC592_002463"
     CDS             3484..4788
                     /locus_tag="PC592_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4056418.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNPNDSNASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQKRFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4851..6113
                     /locus_tag="PC592_002464"
     CDS             4851..6113
                     /locus_tag="PC592_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDF4056419.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKKLPNFKSILEDCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKVKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNKHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNEEVDKALKMNDKWLG
                     DIIQATKDAGTYEDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKNFDAYV
                     DSSGISAQIIVNNLDRLTELRELLEEFKEELFIEKIFTKEEASNLGLEGDFEMVIEGI
                     EGISFGNDLEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKSGVVIEEGD
                     LRAHAATILKIFDLKLDGVEKEAFDFIV"
     gene            6299..8269
                     /gene="uvrB"
                     /locus_tag="PC592_002465"
     CDS             6299..8269
                     /gene="uvrB"
                     /locus_tag="PC592_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDF4056420.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIIEIEDELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNITPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8288..11113
                     /gene="uvrA"
                     /locus_tag="PC592_002466"
     CDS             8288..11113
                     /gene="uvrA"
                     /locus_tag="PC592_002466"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF4056421.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLIATLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFAATNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPREVSKVDGSYTGQFLKKYFS"
     gene            11376..13193
                     /gene="uvrC"
                     /locus_tag="PC592_002467"
     CDS             11376..13193
                     /gene="uvrC"
                     /locus_tag="PC592_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDF4056422.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSCILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEAN"
     gene            13193..14122
                     /locus_tag="PC592_002468"
     CDS             13193..14122
                     /locus_tag="PC592_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDF4056423.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14336..16132
                     /locus_tag="PC592_002469"
     CDS             14336..16132
                     /locus_tag="PC592_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HDF4056424.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVVSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVIIE
                     RQMAIKELLSKDDFSIHIQTLSNIIGKEQKSNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTAIILSFIFCVLGFLPVLPVFLLFIIQLGFSGFGYPKLMQTLSPLFSFSRSIQ
                     VYEKMFEVLEKETFESVYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQIIYIIA
                     CGVLMWNYHCAEALERWKGVYGNQIRDWFESIGEFEALISLTVISHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSRPWVISMVTTHDFELCDLSGNGDVEVVNYHFSEY
                     YVDDKIHFDYKIKYGRCKTTNAKQLMRMAGIL"
     gene            complement(16272..18053)
                     /locus_tag="PC592_002470"
     CDS             complement(16272..18053)
                     /locus_tag="PC592_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF4056425.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCIYGECPQECACEEAK"
     gene            complement(18076..19962)
                     /locus_tag="PC592_002471"
     CDS             complement(18076..19962)
                     /locus_tag="PC592_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDF4056426.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(19979..20476)
                     /locus_tag="PC592_002472"
     CDS             complement(19979..20476)
                     /locus_tag="PC592_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HDF4056427.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(20794..22275)
                     /gene="cls"
                     /locus_tag="PC592_002473"
     CDS             complement(20794..22275)
                     /gene="cls"
                     /locus_tag="PC592_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF4056428.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKIGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
BASE COUNT         8571 a         2986 c         3741 g         7031 t
ORIGIN      
        1 actagattct aaaaaattat taaaaactta atagaaatat taagcataaa gattatgtgg
       61 ttgcaatagc agagaggata cacctgttcc cattccgaac acagaagtta agctctctag
      121 cgctgatggt acttggtggg aaactgcctg ggagagtagg acgtagccac gtaatttttt
      181 tgggtaaatt tataaaaatt aaaaaagttt tattttttat gtttagacct tgtaaatttg
      241 ggacataata taattgtaaa acttaatata gcaaaaataa attactcaat ctcccccact
      301 taaagacctc tatcccccat agaggtcttt tttattttca aaccaaatca tataaaagaa
      361 taaatagttt tatatgactc ttcataaatt taaattacat tgtgatagca aaccatgaat
      421 atgaaaatat agaaaattat agctaatata agctgtatat catcttaact tcagtatatt
      481 taacaaaaaa tgtttataat ttaaccttta ttttaataag tttaccatat attcacttag
      541 tcttaatata tcctttacaa attaagagta ttattaatct ataagtaaat agtagaatta
      601 aattaaatat tttgggagga taaaaatggc agatataaga ctagaaaatg taacaaaatc
      661 ttataataaa aaaaatacag ttatagaaaa tttaaatctt actatagaag atggttcttt
      721 tacagtattg gtaggcccaa gcggatgtgg caaatctact acattaagaa tgattgcagg
      781 gcttgaagat ataacttcag gtaagttgaa aattgaagaa aatgacgtta caaaaacgga
      841 tgctagtaaa agggatatag ctatggtctt tcaaaattat gcattatatc cacatatgac
      901 tgttagagaa aatatagaat ttggtcttaa aaataaaaaa gtagaaaaag aaaaaagaga
      961 aaaacttata acagaagtta ttgatgtagt aggattaaga gaatatttaa atgtgaaacc
     1021 agggaactta tctggaggtc aaagacaaag agtggcactt gctagagcta tggttaaaaa
     1081 tccaaaggta tttttaatgg atgaaccatt gtcaaattta gatgctaaat taagaaatca
     1141 aatgagaaca gaattaatac agttacatca aaaactaaaa tctacatttg tttatgtaac
     1201 tcatgaccag gttgaggcaa tgtcgatggc agataagata gttataatga acaaaggaaa
     1261 gataatgcaa ataggttctc caaagaagat atatcaaaat cctaaaaatt tatttgtagc
     1321 tcaatttata gggaatcctt gtatgaacat actagatata aaaaatgata ttaagtttgg
     1381 atttagacca gaaaaagcaa cactagaaag tataaatata gatggaaaaa atgatgatgt
     1441 atttagctta tttggaaaag tcattactaa agaagtgttg ggaaatgaaa ctatatattg
     1501 tttatctgtt cttaatagtg agataagagt caaaacggaa aatgatatat ttgatattgg
     1561 aagaacttta agaataagtg tattagaaaa agatttatat tattttgata aaaatggaga
     1621 aagaatagaa gatttaaaaa tatgtaaaaa tatgtattct aaaattaaag gagatattta
     1681 tgaaaaagca atttaataaa gcatatttat atataacacc tgctattata ggaactttat
     1741 tgtttatagt ctatccaata attaagacga tatctctaag cttcaaatct ggtagtcttc
     1801 ttagttcaac ctttgagaat gtgggcttga acaattatac agaactttta aagaacccag
     1861 agtttataca aactataacg aatactgcaa tttatacttt ttttatggtg actatatcca
     1921 tatcattagc catagtactt gctgtttggc taaataaaaa ttctataata cacaatttaa
     1981 cgcaaagtat aatctttaca ccacatgtaa tttcactagt atctgtagct gtattgtggc
     2041 tttggattat ggagccacaa tatggctttt taaactggat actatctaca ttacatttac
     2101 caacatcaaa gtggctttca agtgaaagct ctgctttaat gtcactaatt ctaataggaa
     2161 tatggaagac tcttggatac aatattttaa tagtattatc aggtcttaaa tccataccaa
     2221 attatatata tgaagcatct aagctagata atgcaaacaa gataactaat ttctttaaag
     2281 tgacattgcc actattatca ccaacaatat tttttcttat gataacaaca acaactgcat
     2341 cttttcaagt atttgatgag ataagtataa tgacacaggg tggtccagtt ggttcaacca
     2401 atatgctatc ttattatata tatgagtctg gatttatata ttatgacata gggcaagcga
     2461 gtgcagcgag tatgttttta ttagctatag ttatgattgc tacatatgct aactttagac
     2521 tattatcaaa aaaagttcac tatcaataaa gaagaaatag atattataag gcttatcaag
     2581 aaggaggaga aaatggatat tatacaacct atcaaaaaag acaaagttga tataaaaaaa
     2641 atagcatcaa aatcaataga aatattaatt ctattacttt tatctgcaat atttatattt
     2701 ccttttatat ggatgttatc gacatccttt aaaaatccgc aagaaatgat gcaattacca
     2761 cctacaatta tacccaatga tatagtgtta gaaaattata gtacagcatg gcattcaggt
     2821 ccatttttta gatatttgct aaacagtgta tttgtaacag gaagtgtttt aattatacag
     2881 tttttagtta tggttccagc agcgtatgca ttttctaaga ttaaatttaa aggtgaaaaa
     2941 gtgctatttg gacttttgct tgtaggactt atgattccac cacaagtaac ttttctacca
     3001 gtctatatga tgatgagtaa gtttggattt ataaatacgt atgttccgct tataattcca
     3061 tttatgacat cttcatttgg gatatttctt cttagacaga attttatgca ggtttcagat
     3121 gaaattattg aagcagctaa actagataat gcttctgact taaaaataat gtttagaata
     3181 atggttccta tggcaaagcc agcagtaata acatttatat tatttaattt tatataccat
     3241 tggaataatt atttctggcc cttagtaatg acaaatacag atgcaataag aactttacca
     3301 ataggagttg cactccttaa atcttcagaa ggaattactg catggaatgt aataatggca
     3361 ggaaatataa ttctaatttt accaataatt cttgtttata tatttgcgaa taaaaaagta
     3421 aaagaagctt ttatgtattc agggataaaa taaaaaatta aagactaaat ttggaggatg
     3481 aaaatgaagc ttaaaagaaa attagcaaca ggattagcaa taacattatt attaggttct
     3541 ttagttgggt gttcaaatcc taatgattca aatgcatcta aaggagaaaa gactgatagc
     3601 aatattacaa agatagattt ctgggctcct ttaggtggaa ctaatggaga aactgctcaa
     3661 aaaatggttg accagtttaa tagtgaacat aaggatgtac aagtaaatat gttaaagcag
     3721 aaagattact atgaaaatgc aacaaaacta caagcagcct taacatctaa agaccaacca
     3781 gatgtaacat tattagaaat aactcaaaca ggtacattcg catcagcagg tgctttagta
     3841 gatatgagta aatattttga taaaacatat caaaaaagat ttttttctgg tcttttaaca
     3901 aattcatatt atgaggataa gtttgttggt atgccattta atagaagcac tccaatatta
     3961 tacataaata aagatatggc aactaaagca ggtcttgacc cttcaggtcc aaaatcatgg
     4021 gaagagctta aggattatgc tagcaagatg acaaataaat cagaagacac ttatggtttt
     4081 gaaacaccaa tagatatttg gttctatgaa gctatggtaa tgcaaagtgg aggagaaata
     4141 actaatggta aaaaagtagc atttaataat gaagcaggac aagctccagt taagttttgg
     4201 caagatatga tgaaagctgg aataatgaaa atgcctcctg gagaagatta taatgcttgg
     4261 gatgtagcaa aacaagattt tgtaaatggt aaagtaggta tgatatttac atcaacagca
     4321 gatttagcag gacttatgca acaaacagaa ggaaagtttg aaatatcaac agcattctta
     4381 ccaaaaaatc aaaaatatgc aactcctaca ggtggtgcta atctagttat gcttgaaggt
     4441 ggaacagata aagaaaaaga agcaagtgca gaatttatag agtggatgac acaaacagat
     4501 aaaatcgttc agtttagttc atcaacagga tacttaccaa caactgaaga tgcaacaaac
     4561 tcagaaaagt tacaaacatt atataaagaa aaacctcaat ataaggttgc aactgaccaa
     4621 ttacagtatg ctgttgcact tccaatgtta aatggatata aggaagcaac tgataagcta
     4681 atggacgaga ttaaaaaggg acttactgat ttaaatgcaa atccaaaaga tgtagtaagc
     4741 aaaggaactt ctgcaatgca agcagtaata gataaaacaa ataaataatt atatagactt
     4801 gtaagttgat tagaagtatt caataatata taaatgaaga ggtaatgtaa atgacaaagg
     4861 ttatagtatt atcagtggat tctttatttg aaaaagattt ggaatttgta aaaaagctac
     4921 caaactttaa atctatacta gaagattgtt ccatagtgaa aaatataaat tgtgtttatc
     4981 ctactctgac atatccatgt catactagta tggttacagg agtatatcct aaaaaacatg
     5041 gtatatatca taatgaaaaa tttgacccaa ataaagaaaa taaagattgg tattggtatt
     5101 caaaggacat aaaagtaaaa actattatag atgtagcaaa agaaaataat ctaactacct
     5161 ctagtgtatt atggcctgta atgggagcaa atccaaatat agattacaat attgcagaaa
     5221 tatgggctcc tagtagagaa gatgacccaa gagaaacgtt tgaacgaagt tccagtaaag
     5281 ttataatgga tggtatttac aataaacatt gtcattatat tgattggaaa ctagaaccca
     5341 atatggattt gtttggagta aactgttcag tagatataat aaaggaatat aagccagatt
     5401 taatgttaat acatttagct acattggacc acacacgaca caattatggc ttatttaatg
     5461 aagaagtaga taaagcatta aaaatgaatg ataaatggct aggagatatt attcaagcta
     5521 caaaggatgc aggtacatac gaagatacaa attttataat acttggcgac catggtcatc
     5581 ttagagttga taaagttata aatccaaatg tcttgcttaa atcaaatgga tttataaaag
     5641 ttgaaaatgg agaagttaag aattttgatg cctatgtaga ttcttctgga atatcagctc
     5701 aaataatagt aaataactta gataggttaa cagaattaag agaacttctt gaagaattta
     5761 aagaagaatt attcatagag aaaattttta caaaagagga agcatctaac cttggtcttg
     5821 aaggtgattt tgaaatggta attgaaggta ttgaaggtat ttcatttgga aatgatttag
     5881 aaggaagtat tataaaagat tctgatataa aagattataa gtttgctgtt gcgacacatg
     5941 gtcatttacc tacgaaaggt aatagacctc catttatagc ttttggacca aatattaaaa
     6001 gtggtgtggt tatagaggaa ggagacctga gagcacatgc agcaactata ttgaagatat
     6061 ttgatttaaa gctagatggt gttgaaaaag aagcatttga ttttattgta taagttgaat
     6121 aaagtattta ttttccatga attatagact tctattgcaa agatagaagt ctttttttat
     6181 gttttagatt taggtaaaat ttaaatgggt aaaatattta aaataactta aacaatttta
     6241 taaaggtatg atataataat acatgtcagg aactaatgtt cgaaaaagga gtgatactat
     6301 ggattttaaa ataaaatcag acttcaaacc tacaggtgac caaccagaag ctattaaatc
     6361 aatagtggat tctataaata gaaatgagaa attctcaaca ttattaggag taacgggttc
     6421 aggaaaaaca ttcacaatgg caaatatcat tcaacaagtt aagaaaccta ccctaataat
     6481 ggctcataat aagactttag cagcacaact ttacagtgag tttaaagaat ttttcccaga
     6541 caatgcagtt gaatattttg taagttacta tgattactat caaccagaag catatgtagc
     6601 tcacagtgac acttatatag agaaagatgc aagcataaat gatgaaatag acaaacttcg
     6661 acattctgct acagcatcta ttttagagag aagagatact ataataatat catctgtatc
     6721 ttgtatatat ggacttggtg acccaaaaga ctataaagaa cttatgttat ctataagacc
     6781 aggtatgcaa agagatagag atgatgtaat aaaaaggtta atagagatac aatacgaaag
     6841 aaatgacata aattttacac gaggtacttt tagagttaga ggagatatac tagaaatatt
     6901 cccagctagt aatgatgaaa aagcaataag aatagaattt tttggtgatg aggtagatag
     6961 aataacagag attgattatg taacagggaa gattgttggt actagaaatc atgttgttat
     7021 atttccagca tctcactatg taacaacacc agaaagaatt gaaaaggcaa ttatagaaat
     7081 agaagacgag cttcaagaac aaattaaatt tttcaaagaa aatgataggc tattagaggc
     7141 acaaagaatc gaacaaagaa ctaagtatga tatagaaatg ttaaaggaaa taggattttg
     7201 tcaggggata gagaactatt ctagacatat tacaggaagg tcagaaggag aaagaccata
     7261 tactttaatg gacttctttc cagatgacta tttgataatt gtagatgaag cacatgttac
     7321 tataccacaa gtaagaggta tgtatgcagg agataggtct agaaaaacat cccttataga
     7381 gaatggtttt agattacctt ctgcacttga caatagacca ttaaattttc aagaatttga
     7441 aggaaatata aatcagatgt tgtttgtaag tgctacacca ggaccttatg aaattcaaca
     7501 ctcagagaca atagcagaac aaataataag accaactgga cttttagacc caattgtaga
     7561 agtaagacct ataaataatc aaatagatga tttggtagga gaaataacta aaactataga
     7621 aaaaaatgaa agagtgctta taaccacttt aactaaaaaa atgagtgagg acttgactaa
     7681 ttatcttaaa gaaataggga taaaagttaa atatttacac tcagatatag ttacattaga
     7741 aagaacagaa ataataagag atttaagatt agggaaattt gatgttcttg taggaataaa
     7801 tttacttaga gaaggattgg atataccaga agtttcactt atagcaattt tagatgcaga
     7861 caaagaaggt ttcttacgtt ccgaaacagc cttaatacag actattggac gtgcagctag
     7921 aaatgaaaat ggaagagtaa ttatgtatgc tgatagaata actgactcaa tgcaaaatgc
     7981 tattgatgaa acaaagagaa gaagagatat acaaaattta tataatgaag agcacaatat
     8041 cactcctaaa actatacaga aaaatataag agatagtata gaagctacta aggtggcaga
     8101 ggaagaagtt gtatatggaa tatctgatac agatgataaa gatgaaataa gagctaatat
     8161 agataaatta aaatcagaga tgatggaagc tgctcaaaac ttacaatttg aaagagcagc
     8221 agaacttaga gataaagtga aacaattaga agaaaaattg gaaaaataga aaggtaaaaa
     8281 caacattatg gaagataaaa ttataataag aggagcaaaa gagcataatt taaaaaatat
     8341 agacttagaa ttaccaagag ataaatttat tgtttttaca ggtttgtcag ggtctgggaa
     8401 gtcttctttg gcatttgata caatatatgc agaagggcaa agaaggtatg tagaaagtct
     8461 atctgcttat gctagacaat ttttaggtca aatggaaaaa ccaaatgtag agtatattga
     8521 gggtttatcg ccagctatct caattgacca gaagactact tcaaaaaacc cacgttctac
     8581 tgttggaaca gtaacagaaa tatatgacta tttaagacta ttatttgcga gagtaggaga
     8641 tgtgtattgt cctacatgtg gtgaaaaaat aagtcagatg actattcaag aaatagttga
     8701 taaaatgtta gattttccag atagaacgaa attacaaata ctttcaccaa ttgttagagg
     8761 acaaaaaggt acacataaaa aagtttttga taatattaaa aaagaaggat ttgtaagagt
     8821 tagagttaat ggtgaaaact atgaagttag tgatgatata atcctaaata aaaatcaaaa
     8881 acacaatata gaagttgtag tagatagaat agtaattaaa gatggaatag aatcaagact
     8941 agcagattca attgagactg cagttaagct atctgatgga cttgtaatag cccaaataat
     9001 agatggagaa gaaattcttt tttcaactaa atttgcatgc ccagaacatg ggattggtat
     9061 agaagaatta tctccaagaa tgttttcctt taatgctcct tttggtgcct gtgatgtttg
     9121 taatggtctt ggggaaagta aagaagttga cccagaatta gtagtaccaa ataaagattt
     9181 atcaataaaa caaggtgcag tggcagcatg gggttcaaca ggtgttaatg atgacactta
     9241 ttacagtaaa atgataaaaa gtctagcaga gcattttaat gtatctttga caacaccatt
     9301 taaagattta ccagatgatt ttgtggaaga attactttat ggtaaagata atataattgt
     9361 agagtttact tatgagtcaa aatttggagg aactagaaat tataagtcat actttgaagg
     9421 tgtaatagta aacttagaga gaagatatag agaaactaat tcagattaca tgagagataa
     9481 gattgaagaa tatatggctg aaagaccatg tccaaagtgt aaaggtatga gacttaaaaa
     9541 ggaagtttta tctgttttag ttgatggaaa aaatataatg gaagttacaa acttatctgt
     9601 aaatgaatta atcgacttta tggaaaacat aaatcttaca gaaaaacaga gatttatagc
     9661 tcatgagatt ataaaagaga taaaaggaag agccatgttc ttaagagatg taggtctcga
     9721 ttatttaaat ttatcaagaa aagctggaac tttatcagga ggagaagcac aacgtataag
     9781 attagcgact caaataggtt ctgcattagt tggagtctta tatgtacttg atgagccaag
     9841 tataggactt catcaaagag ataatgatag gcttatagcc actcttagac atctaacaga
     9901 cttaggaaat accttaatcg ttgtagagca tgatgaagac acaatgagag aagctgatta
     9961 tgttatagac attggtccag gtgcagggat acatggtggt gaaatagttg cacagggtac
    10021 tttggatgaa ataattgaaa atgagaactc aataacaggt cagtatttaa gtggtaaaaa
    10081 acaaatattg cttcctgaga ctactagaga aggaaatgga agttttatag aaatagttaa
    10141 agcatcagaa aataatctga aaaatattga tgtaaagttc ccattaggta agtttacatg
    10201 cataacaggt gtttcaggtt ctggaaaaag tacactaata aacgatatac tttacaaagg
    10261 tgttgcaagt aaagtgaata gactcaagca aagagctggt aagcataaag agataaaagg
    10321 aattgaaagt atagataaag ttataaatat agaccaaagt cctattggaa gaacacctcg
    10381 ttcaaatcct gctacttata caggtgtatt tgattttata agagatattt ttgcagctac
    10441 taatgaagcc aaagcaagag gttataaaaa aggtagattt agttttaatg taaaaggtgg
    10501 tagatgtgaa gcttgtaagg gtgatggaat aataaaaata gaaatgcatt tcttaccaga
    10561 tgtatatgtt ccttgtgaaa tttgtaaagg tgaaagatac aatagagaaa cattgcaagt
    10621 aaaatacaaa gataaaacta tatctgatat attggatatg aatgtggaag aagctgttga
    10681 gtttttcgaa aatataccaa atataaaaag aaaattagaa actttaatgg atgtaggact
    10741 ttcatatatt aagttaggac agccttcaac tcaattatca ggaggagaag cacaacgtat
    10801 aaaattagct gctgaactta gtaaaagacc aacaggaaag actttgtata tattagatga
    10861 acccactact ggacttcata tggcagatgt agacaagcta atccaagtat tgcaaagact
    10921 agcagataca ggaaatacga ttatagtcat agagcataat ctagatgtta taaagacttg
    10981 tgactatgta atagatttag gaccagaagg tggagataaa ggtggaacta tagttgcaac
    11041 tggaacacca agagaagtat ctaaagttga tggttcttat acaggtcaat tcttaaaaaa
    11101 atatttttct taagtcatat aaattgtgaa aaattttaga gctagatata tacgctaaac
    11161 tgctctttta taagtaaatt agtaaaataa aagttgtaaa tagtaataca aagtaaagtc
    11221 catattactc ttcattgtta aatttgtttt ttaaatcaat tgtagaaggg aatatggact
    11281 ttaacttgtc taaagtactg gaaattgtat aactttttaa atttcatatt ttagggtata
    11341 attttagtat aaaatttaat gttttggagg gcgagatgtt tgatatacaa gagcatttaa
    11401 aaaaattacc ttctgagccc ggagtatatt taatgaaaga caaatacgac catataatat
    11461 atgtgggaaa agccatatct ctaaaaaata gggtaaggca gtattttcaa tcttcaaaaa
    11521 accatacatc taaagtaaaa tctatggtta agaatatata taagtttgag tatattataa
    11581 cggattcaga gttagaggca ttaatacttg aatgtaattt aataaaaaga tacagaccaa
    11641 agtataatgt agtgcttaga gatgataaaa cttatccata tataaaagta actacaaatg
    11701 aagactatcc aagaatttta aaagttagaa gagttcttaa agataaggca aagtattttg
    11761 gaccctatac caatataact gctgtgaatg atactttgga gcttataagt agtacttatc
    11821 caataagaag ctgtaaaatt gatatagata aagcaataaa gaataagaca agaccttgtt
    11881 taaatctaca cataaataaa tgtttaggac cttgtacagg aaatgtttct aaagaagagt
    11941 atggaaaaat gatagaagag attataatgt gtctatctgg caaagaagaa aaattgatgg
    12001 agcttttaaa ggaaaaaatg aatgagagtt ctatgaactt tagatttgaa gaggctgctg
    12061 tatatagaga taagataaag agccttgaag agatgataca gaaacaaaaa atagatgcta
    12121 ctgtaagtga cttaaatcaa gatgtggttg caatggcaag agctcataat gaagcttgtg
    12181 tccaggtatt tttcataaga aatggtaaaa ttgtaggcag ggaacatttt atattagaag
    12241 gtgtaatgga tagtccaagg gcttctatat taagttcatt tgtaaaacaa ttttataatg
    12301 aacaagagta tatacccaaa gagttaatta tagaagatga gatagaagat agttgtatat
    12361 tagaagaatg gctgtcatct aaaaaggggc aaaaagtaac aataagagtt cctcaaaagg
    12421 gagagaagaa aagcttagtt gaaatggtta ggaaaaatgc tgtagagtat cttgaaaaat
    12481 tttctgatat gaataaaaga aaatatgaaa aaagtattgg agcattggaa gaattaaagc
    12541 aaatattaaa tttagaaaaa ttgccaataa gaatagaagc ttatgatata tcaaatatac
    12601 aaggtgtaga ttcaattggt tctatggtag tgtacacgaa tgctaaaaaa gataagaagg
    12661 aatataggag atataaaata aagacagtta ttggacctaa tgattatgat tctatggctg
    12721 agattgtaga tagaagatta aaacatggaa atttacctga cttgatatta ttggatggtg
    12781 gaaaaggaca agttagtgca gtaaaaaaag tactagaact taatgatgta gatatacctc
    12841 tttggggaat gtacaaagat gataagcata gaactaaagg attgatatgc aaagaaaaag
    12901 aaatagagct agacaaaaca actaatttat atagatttat tgctagtata caagaagaag
    12961 ttcataatta tgcaataaca tatcatagaa gtctaagaaa taaagctttg acaaaatcta
    13021 tcttagatga tatacaagga ataggtgaaa aaagaaagaa atcattatta aatcacttta
    13081 aagatgtaga tgctataaaa aaagctacta tggaagaact tttagaagta gatggaatga
    13141 ataaaagcat tgcagataat gtttataatt tttttagaaa ggaagcaaat taatggaaac
    13201 tagcaataaa gtatcaataa gagagataat aaaagagttg aagttaaaag tggtatacat
    13261 gcctgatgat gtagattatt atgtctactc tcaagatata aatagaccag gattacagtt
    13321 tgcaggatat tttgattatt ttgcatatga aagaatacaa atagttggaa agacagaata
    13381 taattttttt ggactaatgg atagtcatat tcgagaagaa gtactagata gatttttctc
    13441 atatgaaata ccagcgttaa taatttctag ggacttggaa attaagccag atgtaattga
    13501 aaaggctaaa aaatataaaa gaatactttt gagcacaaat agaaatacta ctagacttat
    13561 aaatagactg tcaaattatt tggataataa gttagcacca cacacaacaa ttcacggagt
    13621 gctagtagat atttatggta taggtgtact gataaaaggt gaaagtagta taggaaagtc
    13681 agaaacagca ttagaattga ttcaaagggg taatagatta gttgcagatg atgctgtaga
    13741 aataagaaaa ttagatgaaa gtatgcttgt gggtcagtca cctgaattga taaggcattt
    13801 tcttgagata agaggaatag ggataataga tgttagaagc ttatatggag taggggcaat
    13861 caaaaattct aaaatgatag atttagtagt tcatttagaa gcttgggatg aaactaagta
    13921 ctatgataga cttgggctgg ataaagaata tgaagaaata cttggtgtta atgtagagaa
    13981 attggttgta cctgttaaac ctggaagaaa tactgctatg atattagaag tagcagcaat
    14041 gaattttaga caaagaggaa tgggatacga cgcagctcaa gaatttacta aaaaattatc
    14101 aaaactaatt gatactaagt agtactgaat aataatgaac taaacatcat ttaattaaat
    14161 attgattagg attatgtcct acaccttata aattaaagtc aagttgtata tatataatgt
    14221 ttattaataa gatatattat ataaggataa tttaaagtac agcgttagat tataataata
    14281 ctagattaat tttatatttg aatttcatta tataacaaga aagttggaat tttttatggg
    14341 aatagaatat tttagtaaac ttttagaaag tagtactgaa aaagaattgc tcttaagtaa
    14401 aaagtcaaat aacataagta cagcaagatt aatatctttt ttgatagtga tagcagggtt
    14461 tgctattgga ttttacaata aaaatatagt aggtattttt gttggagttg tatcaataat
    14521 aatatttata gcactcttag ttattcatag taaagtaaaa gaagaagaaa catattttaa
    14581 aagtaagagc gaagtattaa ataagtatat taagagattt ggagatggtt ggaaggaatt
    14641 taaaatagat ggtaaagaat acttaaaaga tgaaaactcg caagcaaaag atttagactt
    14701 atttggaaga gcatcattgt atcaatatat ctgtgtagct aatacatctt atgggaaaaa
    14761 ttttttagcc aaatatttgt ggaatgaaaa tccagatgag aatgtaatca tagaaagaca
    14821 gatggctata aaagaacttt tatcaaaaga tgatttttct attcatattc aaacactcag
    14881 taatataatc ggtaaagagc aaaaaagcaa ttcagatagt agtatagaat cgtttataga
    14941 gtatggagaa aataagaatg tgtatatacc aaaatggatg catattttta cttggggttt
    15001 accaactgcg ataattttat cttttatatt ttgtgtgtta ggatttttac ctgttttacc
    15061 tgttttttta ctttttataa tccagttagg gtttagtggc tttggatatc caaaacttat
    15121 gcaaactctt tctccattat tttcatttag tagaagtata caagtatatg aaaaaatgtt
    15181 tgaggtttta gaaaaagaga cgtttgagag tgtatatttg aaagaattac aagacaaact
    15241 ctctaaggga agtggagttt caagaggtgt taaacaatta aattcaatag gaaatgccgt
    15301 aaacctaagg tataatcaga taatatatat aattgcttgt ggtgttttga tgtggaacta
    15361 tcattgtgca gaagctttgg agcgatggaa aggtgtatat ggaaatcaaa ttagagattg
    15421 gtttgaatct attggggaat ttgaagctct aataagttta acagttattt ctcatgtgaa
    15481 ggaaaataca tgctttccag taataaaata tgaagatact ccaagattga aagttgaaga
    15541 agtatatcac ccattaatag cagaaaaaag tgtaatagca aattcaatac aattaaattc
    15601 tcagacttgt attatcacag gttcaaatat gtctggaaaa acaacatttt taagaagtat
    15661 aggtgtaaac ttagtgctgg catatgcagg tgctccagta tgtgctaaga gctttgatgc
    15721 aacctgtatg gctatattta cctctatgag aatacaagat gatgtaagtc aaggaatatc
    15781 aactttctat gctgagattc ttagaataaa atcaatgatt caatatagtt taaaagaact
    15841 gccaatgttg gttctagtag atgaaatttt taagggaact aactctgctg ataggattat
    15901 tggagcaagt gaggcagtaa agaaattatc aagaccatgg gttataagta tggtgacaac
    15961 acatgacttt gagctatgtg acctttcagg gaatggagat gttgaagttg taaactatca
    16021 tttctcagag tactatgtag acgataaaat tcattttgac tataagataa aatatggaag
    16081 atgtaaaact acaaatgcaa aacaacttat gagaatggca gggattcttt aattaataaa
    16141 taggctaatt aataaataca tctatttaga aacataattt aatttatgaa attaataagg
    16201 attgtcttaa attacataaa agtattttaa gacaatcctt ttttaagaat aaattttata
    16261 ctttgttaag actacttagc ttcttcacaa gcacattctt gtggacactc tccataaata
    16321 caactcttat caaagtaatg agtatgaagg tatttatgag ctacatcact atttggttct
    16381 ccaaagaagt ctttataaat agcttgtaaa tcaggatttt catgagattt acgaatagcc
    16441 ttatttctat ctatttcata taacgcattt gcacgtctat caactatttc agtattacca
    16501 tggtgataag gttgaccagc acctccaaca catccaccag gacacgccat gacttctatg
    16561 atatggtatt tacattctcc acttctaacc ttatccataa tctttctagc atttttaagt
    16621 gtatttacaa tacatacatt aactgtagtt ccatcaacat ctatacttgc ttctctaatt
    16681 cctttaagac ctctaacatt agtgaagttt acattatcta aagtcttatt agttatcttc
    16741 tcatatgaag tacgtagggc agcttctaaa actccaccac ttgctccaaa tatagatgca
    16801 gcacctgtag attttcctag aggattatca aaatcttggt cttgaagatt aggtaaatct
    16861 atagcagctt cttttatcat cttagctaac tctctagtag ttatagaaag gtcaacatct
    16921 agtattccag attcacttaa ttcttctctt gaagcttcat attttttagc tacacaaggc
    16981 attacagata caacataaag ttcctcagga ttgattccta atattttagg tgcatagtag
    17041 tttttagcta tagaaccaaa cataccttga ggagatttac agctagatgc taagtttaac
    17101 ttgtctggat aattgtgttc taagaagttt acccatgcag gacaacagct tgttaatata
    17161 ggaagatttt cacctttttg gattctttct ataaactcag tagcttcttc cattatagta
    17221 aagtctgcac caaagtttgt atcaaataca tgttcaaatc caagtgcttt taaagcagct
    17281 accatttttc ctgtagagat tgaccctggt tctaatccaa actcttcacc aatagcaacc
    17341 cttacagcag gagcaacttg cactactata gtcttttctt ttttatttaa aacatcccaa
    17401 agtttaggta cattatccac ttctgttaat gctccagttg gacagacaga tatacattga
    17461 ccacagaatg tacactctgt ttcaaccata tcagagttaa agaatgtact aactagagta
    17521 ttaaatccac gattaactcc agataatgct cctactgttt gtatgtcatt acatacagtc
    17581 tcacatcttc tacataatat acacttagaa tggtctttaa ctaaagattt agtagaagta
    17641 tctttacctg caaaagattt agaaccttga tatcttattt ttcttactcc taaatcagca
    17701 gctatagtct gtaattcaca atctccattt ttttcacata caaagcaatc ttgtggatgg
    17761 tctgatagta ataattcaac aatagttcta cgagcattta atgcttttgc actattagtc
    17821 tgaactttca taccttcctt tataactgtt ccacaagctg gaactaatcc tctctctgtc
    17881 tcaaccatac aaacacgaca agaagcacaa gtatcaagct tatctatttc attcatatgc
    17941 aaatgacaaa ggttgtgtat ttttatattt attaattttg cagcatctaa gatagaagtt
    18001 ccactaggtg ctgaaacgtg tttgccatta atagttaaat taactaaact cattgttatt
    18061 cctcctccaa ataagttatt tcttgattat agcgttaaat gtacaattat ctatacaagc
    18121 accacatttt agacacttag aagtatctat tgtatgttgt tctttaacag aacctgttat
    18181 acaaccagca ggacacactc tagaacattt tgtacaaccc ttacagtcat ctgttataaa
    18241 gtaagaaagt aagttctgac atttaccagc aggacatttc ttatctacaa catgagctat
    18301 atactcatct ttgaaatatt gaagagtact taaaacaggg tttggagcag ctttaccaag
    18361 accacataat gaagcagttt gtatagtttc agcaaggttt tctaggtcat ctaaatcttg
    18421 tagagtacca ttaccttctg taattttagt taatatttct aacaatcttg tagtacctat
    18481 acgacaaggt gtacatttac cacaagattc ctcaacagta aactcaagga agaatttggc
    18541 tatatctacc atacagtcag attcatcaag aacaagcata ccaccagagc ccatcattga
    18601 accgatagaa cttaatgaac caaagtctat aggagtatct aaatgttcag ttggtataca
    18661 tccaccagat gggccacctg tttgaacagc cttaaatttc ttaccttcag ggattccacc
    18721 accaatttca aatacaatat ctcttaaagt agtacccatt ggaacttcaa caagccctac
    18781 attttctact tttccaccaa gagcaaaaac tttagtacca ctagaatctt cagtacctaa
    18841 gttggcaaac caatctccac ctttaagtat tattgcaggt atattagcaa aagtctcaac
    18901 gttatttaag caagtaggag atttccatag accactctta gaagaactat aagtcttcat
    18961 tctaggttca ccacgtctac cttcaattga atgcattaga gctgtacctt caccacaaac
    19021 gaaagcacct gcaccatatt ttaattctaa tttaaagtta aatccagtac ctaagatatt
    19081 ttcaccaagt aaaccgtatt tttcagcttg agctatagct acttttaatc tttctataga
    19141 ttttggatat tctgctctta tatatatgta tcctgtatca gaacctatag catatccaca
    19201 tattgccata gcttctagta cactatgagg gtcaccttca agtacagatc tatccataaa
    19261 tgcacctggg tcaccttcat cagcattaca tacaacaaac tttttatctg ttggaccagc
    19321 tggatttttt gaagcagctt cccatttaga gcctgtaggg aaaccagcac cacctctacc
    19381 acgaaggcca gaagttttta cctctgcaat aacttcctga ggagtaagag aagttaaaca
    19441 tttgcctaga gctaaataac catcattggc aatatattct tctatactat ctgggtctat
    19501 aagaccacaa ttttttaaag ctatacgtaa ctgttttttg tagaaagaca tttcttcttg
    19561 ttcttctact tttttactta aagattcttc ctcatataat aattcctcga caactgtatt
    19621 tctaattaag tggctttgaa ctatcttttc agcatcagat ggctcaactt ttacgtagaa
    19681 aacgttatca ggataaactt ttacgatagg accttgagca cagaaaccaa aacaacctgt
    19741 caaacgaaca ctaactttat cttggattcc tgattttttt atttcatttt ctaattcact
    19801 aactatttct agactgtttg aagatgtaca tccagtatca caacaaacaa gtaattctct
    19861 tcttagtaca ttttccttag aataattttt tcttaagcta agattaggtt tcagctcatc
    19921 agctaaaact tttaattcat caaatgaatt tactttacgc attatttatt cacccctctt
    19981 aacaattcaa ttctaattct ctataagtat ctaatatttc gcttacttgg tcaggtttca
    20041 ctttaccata aactttgcca tttacagtaa caactggagc taaaccacat gcccccaaac
    20101 atcttaaacc ttctaaagaa aatttaaaat cactagtagt ttctccaact tttatgccaa
    20161 gctgtttttc aaaagcactt aagattttgt cagcaccttt tacaaaacat acagtcccta
    20221 gacagacact gattttatac ttacctacag gttctgtagt aaaataagaa tagaatgtaa
    20281 caaccccata tacctttgca ggagctactc caagttttct agcaacatga agttgaactt
    20341 cttttggaag atacccaaat ataccttggg cttcatgtag aacttgtatt aacgcacctt
    20401 cctttgttgc aagagagtca ataaatatat ctagttcgtc aaataattgc ttgttgtgtg
    20461 aaataaaatc gcacataaca aatccccctt ttctttttaa agttattatt tttcaaaaaa
    20521 taattaacca tgagttgacc ccaacattat gtgggtgaac aaaaccaaaa caataaagaa
    20581 agaataatat acaacaattt ctttatttat aaaaacaatg caaaaaagtt acctattaaa
    20641 aataaaaact atactagtct attataatat aaaataattc agaatagtta aaaaaaataa
    20701 aaaaaatgag ctaaattcaa taaaaaaaaa ataatatata taaaaaactt taaaaaataa
    20761 accaaaatgt aaaattttta taaaataaaa gatttataaa actgctgata atagtcttga
    20821 aattgattcc ttgattttta tataagtaga cctagaatta tatatatcta atgttatttc
    20881 ctttgaattt aaaatatcat tttcaaatat aattctttgt tccaatgctt tttttgaaga
    20941 gtacataaat gcattcactt cgaaattaag ctcaaaactt ctgatatcca tattagctgt
    21001 tcctatagag catatagagt catctataac tattgtctta gcatgtaaaa atgcgttttg
    21061 accataagtg tagattttag ctccaaactt taaaagctcc ccagcatatg aatatgatgc
    21121 ccagtataca aatggatggt caggtttaga aggaatcata actctcacat caacaccaga
    21181 taaacaagct atttttaaag tatctataaa agttgagtca agtattaaat aaggactctg
    21241 tatgtatata tactttctag ctttctgaat cattttaagg taaccatatt taatctcatc
    21301 aagttctgat atatctggac cacttgatac tatctgaatc ccaatatttt cagaaggatg
    21361 attagaattt gtatcttctt ctataaagta cttttctaaa tctaaatctt ctttagttgt
    21421 gtatctccaa tcgaggatga atctcatatt taggtcaatt acacaatcac cagtaagctt
    21481 agtatgtgta tctctccata gaccaaattt tggatttcta cctaaatatt catcaccaac
    21541 attatatcca cctacaaatc ccaccttacc atcaatgaca acaatttttc ggtgatttct
    21601 atagtttaag ttaaaattta caattttcaa gaatgatggg aagaagcttc caattttaac
    21661 gccactttct ttaagtctgg aaagtgtact attttttagt gttctaccgc caactgcgtc
    21721 aaataaaagt cttacttcaa caccttcttt agctttgtct ataagaatgt ctattatttc
    21781 agttcctatt ttgtcatctt tgaaaatgta aaattgtatg tttatatatt ttttagcttt
    21841 tttaagttct tcaagaagac tgttaaaaaa ttgactagat tcagcataaa tccacacatc
    21901 gttattattg gtataatgag cattatttga attagccaat gcataaatca tatccttatg
    21961 ttgatgtata tctgaatcaa tttcagatgt agattggagt ttaacctgag tatctagtat
    22021 attgcttttg attatcttat catccttttc tttcaatcta aacatgttgt tttttgaaat
    22081 atttctacca aaagctatat aaagtatgaa tccaagagca ggaatcaata ctaatataag
    22141 aagccatgtt aaagttgtat ttatgtttct tttttctcta aagataaggt ttagtataac
    22201 catgaaatta attatatata ttgtagtaac tgctatttca tatattgaca tttcgaaaaa
    22261 tgatatatca aacataaaat ttcctccttt aaatatttat taaaattaag taattatata
    22321 taacaatac
//
LOCUS       DAMKOJ010000058        21807 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000058 DAMKOJ010000000
VERSION     DAMKOJ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.061"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(110..394)
                     /locus_tag="PC592_002474"
     CDS             complement(110..394)
                     /locus_tag="PC592_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056429.1"
                     /translation="MIVYNKNFYPNDIFSRLDFSKIKRQLKLIDNELSDFGNICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYGIVEEIEKLFKSQVGKFSISTYRN"
     repeat_region   1110..1998
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1314..1342
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            2296..2481
                     /locus_tag="PC592_002475"
     CDS             2296..2481
                     /locus_tag="PC592_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDF4056430.1"
                     /translation="MKIHNLRYTGASLLHLVGTNMKIVSERFCHTDLKLTMNIYSYVL
                     EEMYKKTSNNLSKILFR"
     gene            complement(2634..3506)
                     /locus_tag="PC592_002476"
     CDS             complement(2634..3506)
                     /locus_tag="PC592_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF4056431.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(3900..4478)
                     /locus_tag="PC592_002477"
     CDS             complement(3900..4478)
                     /locus_tag="PC592_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF4056432.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(4535..5251)
                     /locus_tag="PC592_002478"
     CDS             complement(4535..5251)
                     /locus_tag="PC592_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF4056433.1"
                     /translation="MRINKYIASCGIASRRKAEEIILEGRIKVNGSIVKELFFNVDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVKERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISGDEIRKFETGLKIEDYTT
                     APAKIKVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            5442..6527
                     /locus_tag="PC592_002479"
     CDS             5442..6527
                     /locus_tag="PC592_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF4056434.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYINSFIEKNMSNIDFLKTLIPHIQHSLDNVLKEASNFIGKISKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTTRNKADSIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(6681..7355)
                     /locus_tag="PC592_002480"
     CDS             complement(6681..7355)
                     /locus_tag="PC592_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056435.1"
                     /translation="MTRRDLMRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLE
                     KHNYKKAMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEK
                     IKNGSSVIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYS
                     GSSKNNKSSSKNNKKSDSDKSDNNNNSSQNQEKPNSSNPTPAPTPQDTSGGSDSSGNS
                     QNSNNQ"
     gene            complement(7552..8844)
                     /gene="lysA"
                     /locus_tag="PC592_002481"
     CDS             complement(7552..8844)
                     /gene="lysA"
                     /locus_tag="PC592_002481"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDF4056436.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIKYFRAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSDYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIHLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHKAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEV"
     gene            complement(8862..10055)
                     /locus_tag="PC592_002482"
     CDS             complement(8862..10055)
                     /locus_tag="PC592_002482"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF4056437.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(10416..11033)
                     /locus_tag="PC592_002483"
     CDS             complement(10416..11033)
                     /locus_tag="PC592_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056438.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(11203..12903)
                     /locus_tag="PC592_002484"
     CDS             complement(11203..12903)
                     /locus_tag="PC592_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056439.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVFHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQNFITDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNELKDEVIEGTITRISPDVRGGNTNYYVTLDTNKGIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEGTGTDENTDSQDSENQGNV
                     "
     gene            complement(13208..13771)
                     /locus_tag="PC592_002485"
     CDS             complement(13208..13771)
                     /locus_tag="PC592_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056440.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKSISDYRE
                     DYYYDTMALIYLPMNIHRHSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(13932..14645)
                     /locus_tag="PC592_002486"
     CDS             complement(13932..14645)
                     /locus_tag="PC592_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HDF4056441.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLINSQYELELRPTLQEGNLVVSLENVKLGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            14937..16601
                     /locus_tag="PC592_002487"
     CDS             14937..16601
                     /locus_tag="PC592_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HDF4056442.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPENKTEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDLPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPAK"
     gene            complement(16708..17607)
                     /locus_tag="PC592_002488"
     CDS             complement(16708..17607)
                     /locus_tag="PC592_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDF4056443.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEQNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELNIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVYIECADSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(17634..18272)
                     /locus_tag="PC592_002489"
     CDS             complement(17634..18272)
                     /locus_tag="PC592_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF4056444.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KVGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKSTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(18612..19610)
                     /locus_tag="PC592_002490"
     CDS             complement(18612..19610)
                     /locus_tag="PC592_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HDF4056445.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYNYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KEFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADFIQNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(19708..20283)
                     /locus_tag="PC592_002491"
     CDS             complement(19708..20283)
                     /locus_tag="PC592_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056446.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            20600..20863
                     /locus_tag="PC592_002492"
     CDS             20600..20863
                     /locus_tag="PC592_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056447.1"
                     /translation="MIKNTKQITVEVNEILLQEISKITNDENNILTDLINESIVNYIL
                     ENKKHNVEDKDLEEVIKFYKKENTEKTKSAARAIAEAKTHTLY"
     gene            complement(21283..21660)
                     /locus_tag="PC592_002493"
     CDS             complement(21283..21660)
                     /locus_tag="PC592_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4056448.1"
                     /translation="MTITKIPPAELKVMKFIWISDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT         7340 a         3497 c         2244 g         8726 t
ORIGIN      
        1 ataaaaataa tatatactta tttgaaaaag gtaacaactc tttttagttg ttacctaata
       61 atttatctat actttagtat taaatctttt aatttctaac tttcaagtat taatttctgt
      121 atgtagatat gctaaacttt ccaacttgag atttaaataa cttttcaatc tcttcaacta
      181 ttccatacac cttgttttca tactctaaat cataatacac atttatctca cctatactat
      241 ttacacttat tgtataatgc tctttctcta ttatacatat gtttccaaag tctgacaatt
      301 cattatctat taattttaac tgtcttttta tttttgaaaa atctaatctt gaaaatatat
      361 cattaggata gaaattttta ttgtatacaa tcatttcatc caccccttat cattctattt
      421 atgatacttt ataccctaat taataatgca ttaatcatat ttttccatat tattcaaatt
      481 ttcttatata aaaacagatt gcaaatcgat ttttcaatgt tttatattat tatgtttaga
      541 tgtatgtcag taaaatgaaa gtatgagttt ttatccacag attttatgta agttttcaat
      601 acctcataaa ataattatct tccacaataa aagtatggtg cttatataaa aatgctcttt
      661 ttatcaaact atactttttt aggagatagt taaaacatgt aaaatcatct agctaggaga
      721 gttttattat gtctagaatt aatgtatcat tagaataaaa attaaagtag ttgagtcata
      781 ttttttaaag agtttaattt atagtagaaa aacattttat tttatgtaat caaattagag
      841 tatgtattct taaatataaa taaaatgtat aaattaatta gagaacaagg aggtaaaata
      901 aaaaaagaaa gtaagttaat tcaattatat tagataattt tggaattgaa agtttaaaat
      961 aataaaaaca aattacaact ggacaataca tacttaaaaa agttacaaat agaaataaga
     1021 taataattat attatcacat aattaagata aatataaagt gattcaatct ttactcactg
     1081 aaaaaacttc cgttgtccaa tagtgaaaca tttaaattca atatagctaa tataaaacta
     1141 tataaaacga aagttatctc ttaataaatg ttcaatagac tatgctttat ataccactta
     1201 gttaatataa aacgcaactg caagagtaga aataacatta ataatttcac ttacatacca
     1261 cttagttaat ataaaacaat acaaataaga ttttgttttc atatgattca gaaatttaca
     1321 taccacttag ttaatataaa actgtggatt accagttcct aaaaaactaa aagaaaaaat
     1381 atttacatac cacttagtta atataaaacc tatcattaga ttgtgaacct atctctattt
     1441 tcctatattt acataccact tagttaatat aaaactaaat tttgtattct tgacattgac
     1501 atccaatata taatttacat accacttagt taatataaaa ctgatagaga aacttgaaag
     1561 cgaagatgtg ctattaaatt tacataccac ttagttaata taaaacggaa acttgtataa
     1621 tcacaataac tagcttcgtt tcatttacat accacttagt taatataaaa cttcactttg
     1681 atttaactca tctcttttca cacctttatt tacataccac ttagttaata taaaacaatg
     1741 ctgataatag taaaattagc tcaatttctc gatttacata ccacttagtt aatataaaac
     1801 ctgtatattt acaagtttta tataaatatt agtttccaat ttacatacca cttagttaat
     1861 ataaaaccca gttgaaaggt atcctattat ctgcatttct taaatttaca taccacttag
     1921 ttaatataaa acttaactaa aacttgaaaa ccataatctt taagcttaaa tttacatacc
     1981 acttagttaa tataaaaccc taaaataaac gtagaatttc caatactcac acatatgcaa
     2041 ttctcttaaa tttgcagtga gcgaacagta gtgcaaatga taatgtttat caatcactat
     2101 caatacctta catttcaatg cttaaacata ttttcttcaa aaaatcgaac actgcaaaat
     2161 ttctatatct ttattatatc ataaatatat tatatatttt tgtatacaat tactctatca
     2221 tcaatagtat ttataactta gatttcaaat aataaaatca tagttatata atgtattaaa
     2281 aatacctaat gacaaatgaa aatacataat ttaagatata caggtgctag tttgttacat
     2341 ttggtaggaa ctaatatgaa aatagtttct gaaagatttt gtcatacaga tttaaaacta
     2401 actatgaata tatattctta tgttttagaa gaaatgtaca aaaagacctc taataattta
     2461 agtaaaatat tattcagata aacaaaaaac tgactgtcag ttaaatgtca gttaaaccta
     2521 aaaaaggaat ttgccagtta aatgccagtc agttatttta taatatcttt gcttaaatag
     2581 ggctagattt gaacacattt taactcttga aactatttat taatatacaa actttactca
     2641 tacacagaat atcttttcca aatctgctct aaatcatcaa aatgttgttt aatatcttct
     2701 ttttctttca ttccaacaga tatagcaaga gcatttgaaa tactaagagc aggaactaga
     2761 gaatctacaa acgaagccat attactttta actaaaagag tattgtctgc aagtgatgct
     2821 actggtgcaa ataaactatc tgttaatgat attacatgag ctcctttttc cttagcataa
     2881 ttgacaattt gataagattt tttagaataa cgagggaaac taatagcaac tattacatct
     2941 tcttcattta ttcttacaat ctgctcaaaa gcatctccca tatccattct aattatatga
     3001 acattgtcaa gtattatatc taagtaaaaa cctaaatatt gagctactac aaaagaactt
     3061 ctcattccaa gtatatatat ttttctagct cttaaaagtt tattagaagc ttctttaaat
     3121 gctctttcat caatttcttc taatgtagac ctgatattat ctatgtcact ctttaaaact
     3181 ttgtttagta ttgcaaaatc atcagaataa tcatgtgcca tttcaactct ttgtactgta
     3241 gttagtttat tttttatgag ttcttgaagt gcagcttgta atttaggata tccactataa
     3301 cctaatgcat ttgcaaatct tacaactgta gactcgctta ctcctacagt ttcacccaat
     3361 ttacatgcag tcataaatgc aactttatca taattattta aaatgtattg tgctataagt
     3421 ttttgaccct tactcaatct cgtatattga gattgtatat ttgatatcaa atgtttactg
     3481 tccttcattt catttgtttc ttccattttt ttctcctttt agttatataa actattttgt
     3541 tttattaaca ctgtcttttt ctctaaaaat tttatttttt atctcaattt catcttagtt
     3601 tttatcatag cttcttaaac tcataaaatt ctaacttttc tgtaccttat acttcacata
     3661 gtattttcga ttaaatttat tataccatct ttccttgcat tttttaatat ttatccaata
     3721 tttcttttaa atttttcaat ttttactcat ttaaaagtta tctatcttat tttgcatatt
     3781 tagatgtata ttttgttttg agtataagtt attgtatact tattatttaa agtattttta
     3841 ataggtcaca ctatatatat taactcttaa tagaatcttg tcaagttttt tagtatttat
     3901 tatgcttttt tcttttcaat taaaatcaat tgtggtgggt tattgacttg atttaaaaac
     3961 ttagattcta aaacattaaa ttcatcttga tttaaattat taacaaggtt atatatacaa
     4021 tctttttctt cttgacctcc atcatgtcct gtatatatgg caatgcttat tactccattt
     4081 tcttttaaca tttctaaact caactttata gcctttaaag ttgtatctgg ttttgttata
     4141 attgaatgct tcgctcttgg aagataacct aaattaaata aaacacatga aacttcttct
     4201 tttatatatt gattcatttt ttcatgccca tcaaatatca attttactct atctgtatat
     4261 ccttctttct ctaatttttt tcttgtagac tttattgctt cttcttgtat atcaaaagca
     4321 tatacaaagc ctttttctcc aaccttctca gctagatacc ttgtatcata cccatttccc
     4381 atagtagcat caattactat atcaccttca tttataatat tttctaaata aaatttattt
     4441 atatctgtaa ttttagttaa atactttgca tatgccataa tactatttct ccctactatt
     4501 aactttattt cttttttctc aatttatttt tatcttattt tattgatttt aaatatttta
     4561 tttcatcttc tgttaggtat ctatattctc caactttggt gtcttttaat actattttcc
     4621 ccacagaaat ccttcttaag tttaaaactg gatgatttat agctttacac atttttctta
     4681 cttgtctatt tcttccctca tgtatagtta tttcacacac tgaataattt ttttctttat
     4741 tttctttagt tacctttatt ttggcaggtg ctgttgtgta gtcttctatt tttagccctg
     4801 tttcgaattt tcttatttca tcaccactta taattccctt cacactggct acatacgttt
     4861 tatcaatttc atgctttgga tgggtaagct tatatgttaa atctccatca ttagtaagta
     4921 ttaataaccc actagtttca taatctaatc gccctattgg atatactctt tcctttacgt
     4981 ctttaagtat gtctattaca cttggtctat taaattggtc ttttactgta gttatatatc
     5041 cctctggttt attcaatact atatatatat aattttcact tggctttact tttttattat
     5101 caaattctac tatgtctttt tcttcatcaa cattaaaaaa tagctctttt actatacttc
     5161 catttacctt tattcttcct tcaagaatta tttcttctgc ttttcttctg gaagctattc
     5221 cacaagaagc tatatattta ttaattctca tacttaatcc ttccttatct taaattatgt
     5281 gctgtttaat atttttatca atattaattt tgctacatta ttatactata ctagacctta
     5341 attaaaaaca agccaaaaaa ttatttaatt ttcctaaata attgtaattt cttttcacat
     5401 actattaata tgcaatatct gactagatac tatttaagga agtgattatt atttcaaaag
     5461 aaaatataaa atattattta atagtcgtgt ttattggaat tttatttttt aaatttatta
     5521 atactccatc agactttata tctagtattg aaggtttctt aaagtttttt agcccatttt
     5581 tattagctat tttacttgct ttacttttaa atccacttgt gatgcttttt gaggtaaaat
     5641 tcaaagcaca tagactttta gctatttttt tatcttatat atttataggt tttattttag
     5701 cctttgccat taggttattg attccatcaa tagctaatac attaaataga ttgataaatg
     5761 aaatgcctat gtatactgat tatataaata gtttcataga aaaaaatatg tcaaacatag
     5821 attttctaaa aactttaatt cctcatatcc aacatagttt agataatgta ttaaaagaag
     5881 caagtaattt tattggtaaa atttctaaaa acttcttaat ttatacactt agcatatctt
     5941 ctatgctatt taatatgaca atgggattta tactatctat atacattata tatgacaaag
     6001 aaaaaattgc attgggattt aagagatttc tatattcttc tactactaga aacaaagcag
     6061 atagcattat agaatttttt aggactactc atgatatttt ctatgattat ttacttggta
     6121 gaatattaga ttctcttatt attggtataa ttgcattttt aggatttcaa tttgttatca
     6181 gaatagaaaa tgctttattt ttagcttcaa taatattctt aggtaatata atcccatatt
     6241 ttggtccttt tattggtgca atccctccaa tagccatgac tatattatat agtccacaaa
     6301 aaactatatg ggtcattgca tttctattta tattgcaaca attagatgga aattttatag
     6361 aaccaaaagt tatgggtaat caagttggta taggagctat ctgggtaata tctgctattt
     6421 tagtaggtca atctctattt ggtttcatag gagtttttct ttcagtgcca atagctgctg
     6481 ttgtaaaaac ttacgttgat aaatatatag acaatcggtt gcaatagttt atctctactg
     6541 ttatttagct tttagtttaa attttaactg ttatttgtca aattattttt aaaaaaatac
     6601 ctcttagtaa gaaaaactta ctaagaggta ttttttataa tatatatttt gttcatcaaa
     6661 tttatgtata tattttatac ttattgatta ttcgagtttt gagaatttcc actactatct
     6721 gaaccaccac tagtatcttg tggggttggt gctggtgttg gattactact atttggcttt
     6781 tcttgatttt gagaagagtt attattattg tcagatttat cactatctga ttttttatta
     6841 tttttagaac tagatttatt atttttacta cttccactat aagaagattt tcttgcatct
     6901 gattcaactc tatacctatc ttctccagct gtatcttttg cctttttctt tctttgttcc
     6961 tctgcttcat tttgttcttt ttctaattta gttaactctt ctttcttttt agttgcctct
     7021 tctttaataa cagaggaacc atttttgatt ttctctataa gtttaagttc cttgattgcc
     7081 ccctcataat tttttaattc ttcaaactct gtcatatttg acattctcat agcttgcata
     7141 tacatagctc ttgcattctc attagtacta tcttcttcca gtgcagagga taatgattcc
     7201 atagcttttt tatagttatg tttttctaaa tacgtttttc cttgctctac taaatttatt
     7261 tcatcttttt tattaaatga acatcctaca agaaatatag ataatatcga tattaataaa
     7321 attactcttc ctctcattaa atccctcctt gtcatatact ttaaatttta tcataattat
     7381 aaagttttta aaatatttta tatttattac aagaaatttg ttagtaaaac gaaaaataag
     7441 cagatatgct acgaacaata taataaacca aaaattaatt tagatatata tcatagcaaa
     7501 tctgcttata ataaacttta atattcaatt tttactatat gcttctccat tttatacttc
     7561 taaagctaat aagtcctcat agctttgtct cttacaaatt atcttatcat ttccgtcaaa
     7621 tactgatact actgctgccc ttggtatttt attataattt gaagacattg aatatccata
     7681 tgcaccagtt gatgttgtta taagtatatc tccactttta atgtccatta tatttatatc
     7741 tccaattaat atatctccac tctcacaaca ttttccagct attgttacat gattcatagc
     7801 cttgtgatta attttattca caatactaca ctcataacta gcttggtaca acgaaggtct
     7861 tacattatct gtcataccgc catctacact tacatatacc ctaacatctt ttatatcttt
     7921 tatagaacct actgtataca atgtacttcc tgcatttgca actattgacc ttcctggttc
     7981 tattaccaat gtaggtactt ctattccaag ctctttacat gaagtttctg ctttagtgat
     8041 tatagtttca caaaactctt ttatagtttt aggtttatct ccttcgctat aataaactcc
     8101 aacgcctcca cctaggtcaa tctctgttag atgtatgttg aatttttctt ttatttcttt
     8161 tactaagttc atcattatat ctactgtatc tatgtatggt tctacatcaa atatttgtga
     8221 acctatatga gcgtgaagac ccacaagttt gatattttta tagtcactta atttttctat
     8281 tgctctaaat aaatctccat ttactaaagc aaatccaaat ttagaatcta tctgtccagt
     8341 ttttatataa tcatgtgtat gagcttctat accaggagtt attctaaaat atatctcttg
     8401 agttttacct ttatcttcac ataatgcttc aagtaaatct aactcataaa aattatccac
     8461 tacaaattta cctacaccta aatctaatcc catgtttatt tcttctttag tcttattgtt
     8521 tccatgaaag aaaacttttt ccataggaaa atttgattta taagctgtat acaactcgcc
     8581 tcctgaaact acatctagac acatttgttc ttcatttata agattacaca tataaagagg
     8641 taaaaaagct ttccccgcat aagcaacctt attttttccc tctctagctc taaaatattt
     8701 tatatattct ctacaatttt gtctaactaa agcttcatca aatacataaa gtggagtttg
     8761 atatttttta ctaagttcta aacaactcac tcctccaata tataattcat cattatttac
     8821 agtcatagtt ccatgaagtt tcataatagc ctccccaaat tttatatatt aaatacttct
     8881 gctattttct ctatagctac ttgcttatca tcagaattta tagcacaagt tatacgaatt
     8941 tctgatgtag ttataagttt tatcattata ccattttcat tgaatatctt aaatacttta
     9001 gcagcaactc cagaagtatt tttcatacca agacctacta aggaaaattt agtgatatta
     9061 ttatcaataa ctacatgttc ttcatctgta tatttagata ctatcttttt acattctccc
     9121 aattcttctt ttggaactgt aaatgataca cttatcttat ctaaaatagg tgcagtttgg
     9181 cttatcatat ctacacttat acctatagtt gctatatctt caaataagct agatatattc
     9241 tctgctttaa aatcttttat tgttatagaa ctgtcatcat cactagtagc taatcctgtt
     9301 attactttat cctctaattt catgtctttt ccccctctta tatatgttcc tttttctgta
     9361 ccacatgtac gtccaacata aatttcaaca ccatattttt gtgcaagctc tatacttctt
     9421 gaatgcatta cttgtgctcc taaacttgct aactcaagca tttcttcata ttcaatctca
     9481 tcaagcttgc tagcctttga atattttctt gggtctgtaa aataaattcc atcaacatct
     9541 gtatatatct cacattttcc atttaattta actgcaagag ctacagcaga tgtatctgaa
     9601 ccacctcttc caagagtagt tacatcacca tcttcgttga ttccttgaaa tccagttact
     9661 atcacgacat ttccttcatc taaactattt tttattctgt ttacgtttat atcatcaatc
     9721 tgagactttc catgaagacc actcgttttt atatttaact gataagcatt ataacttata
     9781 gctttacatc caagtgcatt taatgctatt gataataaag atgctgaaat catttcacca
     9841 gtagacatta aagcatctaa ttctctctta ctaggttcat tactcaattc ctttgccaaa
     9901 gttatatatt catcagtgga ttttcccatg gcagacacaa ctattaccat ttgtggattt
     9961 tcttttcttc gttctattat gttttctgct attgatttta ttttttcagt atctgctact
    10021 gaacttccgc catatttttg gacaattata ctcatgcttt ctccccctca agctaaattt
    10081 tgataaataa aaacgcccaa aggtatactt tggacgtgta aatttcatag accaagtaac
    10141 cttgtagctc accactttaa aagtgacagc cttatgcata ttctgcataa gtccagaaaa
    10201 tttgtccgtc aacaaaattt cttcggctat ataccctttc atcaattatc aatgcttacc
    10261 agctcctatt gaatactatt gaatacagct acctctaccc taggctcatt atttttaatt
    10321 aatttattaa tatagtttta tcatattcta tataatattg caacaattat tttacaaaat
    10381 gtggcaaatc aatagttttc ttttctaaaa ttagcttata tacaattaaa tagtttattt
    10441 aatcccaaat ctataaaatt tatactatac tcattatcat atctctctaa atcatttaat
    10501 tcagataagt tatctggtgt aactaccaaa acgtttggca ctttaaaaaa tggaattgta
    10561 gatttatcta tttttttaga aagattttcg tatttagaaa tgtctatttc attatttaag
    10621 tcaacatcta ctagaacttg ctttatatta ccaaattggt ctgtatattc aataaataaa
    10681 tcgtatttaa catcatctac actaacattt cggtaaaatc tttttacatc acaacctgca
    10741 gtattgattc taacaactaa ttctgatcct actagagcct ttattaaatc atctccctta
    10801 aaaagcttac taccatttaa atagtataca taagagaggt ctttataatt ataataatct
    10861 acatcacaag gatatttttt tagtgtatat tcactacaca tttttctcaa agttttttta
    10921 aaattttttt tattgtatct tttttggtct ccataaattt ttctaaattg agactctgta
    10981 acacatctaa ccctgctaat taaaagtaat atctcttttt ccatattcgt catagtacat
    11041 tctccttgaa gtattatttg caaagttgta ctaatattat attaatttta tgacattaaa
    11101 tttacaaaga attaaaataa aatagctaat ttttatagaa ttaaattcta taaaaattag
    11161 ctattactat gttaaatatt gttataagtc tttttattta aattatacat taccttgatt
    11221 ttcagaatct tgagaatccg tattctcatc agttcctgtt ccttcttttg cttttttatc
    11281 ttcaaagttt gcaatattta gattatcaaa ttctgacatt tctattacac cagattcttc
    11341 ttttgaatac gatattttga ctttatcacc aacctgagtc aatggcaatt cgctagatac
    11401 ttttgaagta gccctaaata ttataccttt atttgtatct aaagttacat aataattagt
    11461 gttaccacct cgtacatctg ggcttattct tgtaattgta ccttctatta cctcatcttt
    11521 taattcatta tcaagtttca aatcattccc tttagattct aatgcatctt tatagtttct
    11581 taatgcttca ttcttatctt cacctattcc aagtacatta taatcttcaa cagatacaaa
    11641 tgcaactctc ttaacaagac cagccttatc ttttaatgat gatacatatg ttggctgacc
    11701 caatatatta tacattacag ggaatgttgc ttcataattt ttttcttgaa cattaccttc
    11761 agctgatttc attgcagccg tttcagtagc tcctggttgt ttatataatc tagcttcttt
    11821 tgttctagaa tcaactaaca taaatccaat tgtagattca tctccacctg aggatgttat
    11881 acctgtatac caataagacc tattatcatt accataaact aatgatgtac cttctgttgg
    11941 tactaaaact cctttttctg atataacaga atttaaaaat ccattaacat aaacgcccca
    12001 gtctttaatc tggtctgtta taaagttttg tggttgtatt ctatccaccc atttaggtgt
    12061 gtttttaaca tcataaacat ttatttttcc agtttctgca tcaacagtgg ctattcctgt
    12121 ggcatttgct cctccatatc caattttatg ttcatataaa cttacaaccc aataaggtct
    12181 tccttcatca tttatttcaa gagtgaaatc tgtcatacca acatttacaa taccatgtat
    12241 gtataaatgt ctttgtaaat cttgatgtaa ataggcttct ggttggtaaa ctatctttat
    12301 tggctttcca tctatttctt gaactaattg gacatcttga ggattactag ctgatacttt
    12361 tacataacca cttgtaccac ttagagatgt tatccattta attatgtccc tgtgaacaag
    12421 aggtgctacc cagtacagct ctccatctac attttgtata tgaaattttc ctaatttgga
    12481 tacactccct attgcaggaa cttctccaag ctttttatcg cccaatttca ttgccatatc
    12541 ttcatctaca agacgaatgt catttacact gacagggcta atgtcatcag taaatttact
    12601 ttcagttact tttcccaata gttctctata tgattttgca tgaaatacag gagtagaagt
    12661 tataaaggga actaccacaa tatacacaag caaagctatt gctattgaaa aattatattt
    12721 agccatttta gatgctcttt catttctatc taacatcata tctagtattc ctgctacaac
    12781 aaagaaaatt attcctactg aaaataaaga tgtaaaatct aatcttagta caggtaattt
    12841 aataaatgca taaattatta caattattaa tgcaactcca tatgttttaa gatatcgttt
    12901 catttaatac tcctctctaa aaaatgttat tattactatt atatccatat atttacaaaa
    12961 aataaatatt tatcatattt attatgtatt aagatatctt tatatattta tagttctacc
    13021 tattcaatta tatgtaatat atatatccaa aaatattata aaaatacaaa taatagcaga
    13081 aatttaaaaa ctgaagaaag tattctaact aagatttaca aattcttaat cctatcgaag
    13141 ttaaactact atcttcagcc taattgtcta gcaatatttt ttatatgaaa aactctaaat
    13201 caagttttta aatgtttgcg atttttgata cataagaatg ttgtctagaa ttatattctg
    13261 ataataaacc ttcatactct aaggttaaac cagataaatt ataaaaatca tttggtgtta
    13321 cttcaaatgc ttgtttattt aaaatgtcta tctcactttt ttctaacatg tcagcaacaa
    13381 aatttgaaca tacatattta tattcagagt gtctgtgaat attcattggt aaatatatta
    13441 atgccattgt atcgtaatag taatcttctc tataatcact aattgatttt atatttttat
    13501 atagattttc atattgtaaa ttatctactt ctaacgaata taccctacac acagtgtttt
    13561 ttcttatagc atataatcct tgatttatat tttcttcaac aaaacctcca ataaagggat
    13621 tccttggatt tagtctccca aaagaataca ttggttttag attttcattt aatgatattg
    13681 acacatgtgt atacagtttt ttacttatat tccttattaa gtaagataat atagttcctg
    13741 tatatgttgt tacaatatag actttattca tcatttcccc ccaatctagt aactaaataa
    13801 tattatacat ttacaattta atatcataag atattctaac ataataaatg tagttttaca
    13861 aattttgatt ttaaggtact ttaacattat ataaaatata ataaaaatat aaatataagt
    13921 tttctatatt tttaaccaac agacgttttc ttcaaattaa tcagatgatt tagtatatct
    13981 tgaaccttcc cagaatcctt taaatatcct aatgccccgt ttatttgtga ttttaaatct
    14041 atttctactt ccatatctaa gtcaacattt ccttttttta tagatatatt tttaagcgtt
    14101 attgggtaaa gataactttt ttctaaagta atcttatttc cattaacctc aaatggaact
    14161 tttttattgt agttacttaa tattttttct aacattttat cacttagctt aaattttcca
    14221 agtttcacat tttcaagact tacaactaag tttccctcct gtaaagtagg tctcaattca
    14281 agttcatact gactatttat caaaccaaat accttatatg gtcctgctac ctttatttta
    14341 ccatttttca tttcaacaaa attattttca agttcattaa taccatgttt ctgcatcaat
    14401 gtatagatta aatttttaaa ctcttcctct gaaacagata tttttccaac cattctaagt
    14461 ggatttttta ctacttccat agaatttata tatgaacctt ttgataaata ttcttcatct
    14521 ataattttat tattttgtga actaacatca tatctttctt ttggtgtcaa gatatataca
    14581 acaatacctg caagtactaa aacaataaca attaaactta ataaaatctt tgcaaccttt
    14641 cccataatcg tctcctttac aaatctgtca acagatttaa aataaattta gataactaac
    14701 ttcacataat attcttaaca atatacatac tataatacag tcttttaaaa attaattcaa
    14761 ctaatctcat tttttgtaaa taaactgtaa aaacatgttt ttagtataaa agttaatatt
    14821 ttgcataata ctcttaatta cacctttatt tttttctaat cttggattaa aattaatatt
    14881 atgcaataca gtgtagtgtt ctgtattata atcaaattaa ataggaggta tagaatatgt
    14941 caaatgaaac gaactcatct aactttataa aaaatattat tataaacgac ctagaaacag
    15001 gaaaacatga cagtataata actcgttttc cacctgagcc aaacggatat ttacatattg
    15061 gtcatgcaaa aagtatatgt cttaattttg gattagctaa ggaatttaat ggaaaagcta
    15121 atttaagatt tgatgataca aatccattaa aagaggatgt tgaatatgta gaatccataa
    15181 aagaagatgt caagtggtta ggatttgatt ggaacgagtt aaattttgca tctaactact
    15241 ttgatgaaat gtataagaga gctttaatac taataaaaaa aggtaaagct tatgtatgtg
    15301 atttgacaca agaagaaatg agagaatatc gtggtactct aactgaacca ggaaaagaaa
    15361 gtcctcatag aaacagaacg attgaagaaa accttgattt atttgaaaga atgaaaaatg
    15421 gtgaatttaa agatggtgaa aaaacattaa gagccaaaat agatatgtct tctccaaata
    15481 taaatcttag agacccaatt atatatagaa tatctcattc aacgcaccac aatacaggag
    15541 ataaatggtg catatatcct atgtatgctt ttgctcatcc aattgaagat gcaattgaag
    15601 gaataactca ctctatatgt actttagagt ttgaagacca aagacctctt tatgattggt
    15661 ttgttaaaga atgtgagatg gaaaacatac ctagacaaat agaatttgct agacttaata
    15721 taaataatac tgtcatgagt aaaaggaaat taaaacaact tgtagatgaa ggtattgttg
    15781 atggttggga tgatcctcgt gttcctacaa tatctggaat cagacgtaag ggatatactg
    15841 cagaagcatt gcgcaatttc tgtagtgaaa taggtgtatc aaaagtcaac tctacagtag
    15901 atagtcaaat gcttgattat ttcctaagag agaatttaca accaaaggct cctcttacta
    15961 tgggagtttt aagaccttta aaacttatta taactaatta cccagaaaat aagactgaga
    16021 tgcttgaaat agagaataat gctaaagatg aatctcaagg aaaaagatta gttcctttct
    16081 ctagagaatt gtatatagaa caggatgatt ttatggaaga acctgttaag aaatatttta
    16141 gatttttccc aggaaatgaa gtccgtttaa aaggtgctta ttttgtaaaa tgtactgatg
    16201 taattaagga tgaaaatgga aatgtagttg aaatacatgg tacctatgac cctgagacta
    16261 agagtggctc tggatttaca ggacgtaagg taaaatctac aatacattgg gttgatgcta
    16321 aatcagctat accatgtgaa tttagattgt ttgaaccatt aattcttgat gatttacctg
    16381 aaaacgaggg caagcatttc ttagaacaaa taaatcctaa ttcattggaa atattacaag
    16441 gttttgttga acctacacag ataaaagatg ctaaaccttt tgataaattc caatttgtta
    16501 gaaatggatt ctttagtata gataataaat atacaactga tgaaaaattt gtatttaata
    16561 gaatagttcc tctaaaaagt tctttcaaac cggctaaata atcttacaat caaaaaatga
    16621 agacttaaaa tataaattac ttctactata aagaaactta gttagaagta attttttatt
    16681 tcagccttca ttatttactt taaatgatta acttttttca ctacagattc ccataacttc
    16741 tattccatct tttatacatt ctatgttaag gggaaaatct ggtccttttt ctccatcaat
    16801 atccgttata agtgaatctg cacattctat atacaccttt ttagttttaa agtatagtat
    16861 ctcatttcca ttatattgat ctaaataatc acctctaagc acacttatca aaactggtat
    16921 tgattttggt attggcattc ctttaaaaat aatcacatcc agatacccat catctatttc
    16981 agccttatat gctagattta tatttcctgc tgttttgcca ttaaaaatca acataagata
    17041 catatctcca tcataataca tttcctcaga agatactttt atcttaaatt ttctcatata
    17101 caatgcttct tctattccct ttatataata agaaattctt ccaaatgaat tttttaagtc
    17161 tgtatttatc ctttgtgata catctgtaaa cataccagcg cttgcaacat ttataaagta
    17221 cttattattg actttcccta tgtctatttt cttgggtttt gaatttatga tttcatttat
    17281 agcttctttt atatcaaatg aaatttgaag agcatttgaa aaatcatttg cagttcctgt
    17341 aggcaaaatt ccaattggaa tttttatgtt taattctttc attgcattta ctactaaatc
    17401 tacagtacca tcaccacctg ctatcaatat gtgttcataa gaactatcaa cttccttaaa
    17461 tgcattcttt acaggttctt taatagtcaa tctatagggt atcaataagt aattttgttc
    17521 ttgatataat tctatgatag tgtctaaatt tgataatatc tttttttcac ctgaattagg
    17581 attgtatata agttttactt ttttcattat ttctccttac tcattttatt cttttagtat
    17641 ccaaaatctt cattcaaaaa aatcacatgt attctttctg gtgttaattg tctttttata
    17701 agtgtataac tacagcatat tcttcctgga cttgaacagt ctatacatat accagtactc
    17761 ttacatccag tatttgtact taatctttta caattggctg gagcagctat tgtttttgtt
    17821 ctttttatgg cttcatctac atctttaact attttattta ctcctgctat aactatcact
    17881 ttatcaggtc catatatcat ggcagcaact ctattaccat tcccatctag attgtaaagt
    17941 tctccatcct ctgttattgc attagtactt gtaaaataag catctgcaga aaatgacttt
    18001 ctgtatattt ctttcatttc ttctggtttg atatcttttg catatctgtc aagaaaatta
    18061 tatttttctc ttataaaatc aatcactcct gtttcaaata aggtcataga acctccacat
    18121 cctactagag aaccaacttt aactatttct tcaatttttt taagaagctc ttctttatta
    18181 cttactaaat accctttcat attattattt tctaaagatt ttattgtttt ttctattctt
    18241 ttttcattaa gccaatttaa attttgatcc attttaactt cccccttatt tttaatatgt
    18301 acctaattat ttataaactt tattttcttt ataagtttat tttagtaaat ctaaaaaaaa
    18361 atacaatata aaacttaaat tgttttccat aattttttcc aaagtaactt actcaatcaa
    18421 aaaaggaaag tagatgtact attctacttt ccctatattg tatgtagtat tatatattgc
    18481 ttaaaatcta tatattaatt atatgtttca tattatagaa tatcacagtt aatttaaatg
    18541 taatactata ttcttttcaa acatataaat tgtattatta aatttaatat atccaacttc
    18601 agtaagtctt attaatttga tgaagaagat gctatagctg cacttgtcgc tgccattaca
    18661 catgcaattt gaatagcaac aacaatattt aaaaatatat tattagttat agagcctata
    18721 ttattctcat tttgtatgaa atctgcataa attgaagcta caatagcaga actaatcatt
    18781 actctattac tttttcctaa agaccaattt ccaaagcctt tttcttcttt aagtttattt
    18841 gaaacatttt ttatctcttc tattatttca tcttctctat aatctaatag tgaaattgct
    18901 cctattattg gatatccata ataattcatt ttacaatcat tttctttaaa ttcttttttg
    18961 agttcaatag tctttttaca tttaagcata gtcctatcat cactaaataa aagaatttgg
    19021 gataatgctt gtaaatcatt tcctttataa aaaccatttt catttagaaa ttcataacat
    19081 ttttctatgt attctaaatc ttcgtctaaa ttttttgaat gaattgcaat aagtgctata
    19141 ttacaatagt catcactaga agttagaaat ggatgttttt tcctcatata gttatatatt
    19201 attttcattt ttgatataca tgtaagataa tccattttct ctctattttc ataaactatt
    19261 gatgctgtaa gtggtaaata tgtatcgccc caaaattttt cacttttaag ttctttgtat
    19321 atatctaaaa tcatcttaaa actactttct ggatttgatt caaatgaaag tagtgttgcc
    19381 atataaaaca tattatatcc tctaaaatta gagaataatc cagtattttt tttaataagc
    19441 tctattcgtt cttctactag tctaggactt attctcttat tcttaagagt aaatgcaagt
    19501 gcacaactat gttgtatcaa tcccatttgc caagaacctt taacttcatt taatgctttg
    19561 taattttcta ttagtaagtt tacttttcca tttataaaag actgttccat attgccctcc
    19621 tagtaatata tctcattgta ttaatagttt tatatttatt atatatatat taaatattac
    19681 aatcaataca tattacttca aagagcatca ttcttcaaca ataatgtaac cttttttgta
    19741 atgtcttccc atattattga ctctatcata gtactctgat tcactttcat tactccattt
    19801 tggcacaaat acatctattg cattagaatt gctaaaatac ttactagacc ccctatccat
    19861 aacagttttt aattttccat ctacaataat cttagttcca aaactcaagt gattgtttgc
    19921 tacaaaacca tcttctaaat catctcctgt agcagttatc gctccatatc cattttcttg
    19981 attgagactt gtgtaataac taacttcaaa agttataggt actagcttct ttattttaat
    20041 acctaactga ttttgtaatt tctccttttg tactttcagc ttatactcat cactattttt
    20101 atagtcttcc ataccttgat tatacttgga attaaagctt ttacctgact ttactatagt
    20161 atcgatattt actatagatt ctttacaatg atctgcatct atttttgttt ctccatttac
    20221 caataatgga gttaaacata cactacatac aacacatgta atcaatgctt ctttaagctt
    20281 cataaattcc ccccttatta ttttgatata ttagcatatt taatattata tgtctacatt
    20341 tagatttaaa taccacaccc atttgcttca agaagttgtc ttatatttaa ttcaccttaa
    20401 acacttataa atcctttatc tcagaatcat atagaataaa gctttttctg ttaaatatat
    20461 tttgttaatc ttttaaaacc taaaaccact tttatttaat tttctatttt ttagaattta
    20521 agaattaaaa ttctataatt ttaaaacata ttgaatttat ttttttgaga tgatataatt
    20581 tttttaagag gtggttgata tgataaaaaa tacaaaacaa attacagtag aagttaatga
    20641 aattttatta caagaaatat ctaagataac taatgacgaa aataatattt tgacagattt
    20701 gataaatgaa tcaattgtaa attatattct tgaaaacaaa aaacacaatg ttgaagataa
    20761 agatttagaa gaagtgatta aattttacaa aaaagaaaat actgaaaaaa ctaaaagtgc
    20821 agcaagagct atagctgaag caaaaactca tactttgtat taataaaaaa aagttcctaa
    20881 aaattaggaa cttttttatt ttaataatta ttaatatatc tcaatattta tcaatataaa
    20941 catgtttaat acaatctatt gtatacttat cttaccctag aaataatcaa aacaaaaata
    21001 aaattatgcc ctttatatct aaaacaacta atttacatga ttaatataca aaaattctga
    21061 cttttaaatt cgtatacaat atcaaactaa aataatatta atgaccccaa tataaattaa
    21121 attctaacag gtttgatttt acatcaaact tattgtatta atattaaata acaagacaaa
    21181 aatacttgta aaaatcacaa attttacata aaactttata tttgattcat ttaactaatt
    21241 attgtaaaaa ctatttattt tatgataatt aactacacca aattattcat cttttttaat
    21301 atctttaacc catttttcaa cagagttcaa ttcttcttca tttaccccct ttttgaacaa
    21361 agatttcata aaactctcaa tagaacttcc atgcatatta tctaaaaaag tttttgtttc
    21421 aaaatgtaaa tactcttctt cgccaataag aactgtataa tgtgtatgtc tatcaatctt
    21481 tcttgcactt aagaattgct tatttactaa tcttgataaa agtgttagtg ttgtagtttg
    21541 cttccaatta tatagttttt ccatagcttc aatgacatct tttgatgcta ctgtaaaatc
    21601 tgaaatccaa ataaatttca tgacttttaa ttctgctggt ggtatcttag taatagtcat
    21661 atgattttac actcctctca aacttctaca taattaaata ctatattaat agacttttcg
    21721 agtcaaaggt tttatttaaa atatctcatc caaatttatt aatacaaaaa atttatattt
    21781 ttatttaaaa ttaaacatac aatctat
//
LOCUS       DAMKOJ010000059        21568 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000059 DAMKOJ010000000
VERSION     DAMKOJ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21568
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.062"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            19..1299
                     /locus_tag="PC592_002494"
     CDS             19..1299
                     /locus_tag="PC592_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDF4056449.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPTEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKILNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIKNNICSA
                     TAIRTSLKENINFFHLKNVIPEKTYNILNEKIDNGFLPMFDDLFFDTLKTIILRDMDT
                     LKDYFEVNEGIENRIYRDIFTSEFLHELQLSIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREVLKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKSTNIYNSVYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1562..2953)
                     /locus_tag="PC592_002495"
     CDS             complement(1562..2953)
                     /locus_tag="PC592_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF4056450.1"
                     /translation="MYKLVDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEVINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLVPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(2964..4184)
                     /locus_tag="PC592_002496"
     CDS             complement(2964..4184)
                     /locus_tag="PC592_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HDF4056451.1"
                     /translation="MSKIVVNQDKITDLKRVLEICPFGAIEEKSGVVEISAGCKMCKL
                     CVKSGPKGAFEFVESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCNNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFINKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSVPEKIENATGKVTLCKIEKKDLSSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMMYKLANKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDDNQKYMASAAK"
     gene            complement(4198..4986)
                     /locus_tag="PC592_002497"
     CDS             complement(4198..4986)
                     /locus_tag="PC592_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF4056452.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKQEKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEAKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLDTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSSALVNKLEELKLV"
     gene            complement(5003..6277)
                     /gene="larA"
                     /locus_tag="PC592_002498"
     CDS             complement(5003..6277)
                     /gene="larA"
                     /locus_tag="PC592_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HDF4056453.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRKINPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHVSTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSILPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSEVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMIAACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTVPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEKATSIVGKDSKVVVIPDGVSVIVK"
     gene            complement(6395..7108)
                     /locus_tag="PC592_002499"
     CDS             complement(6395..7108)
                     /locus_tag="PC592_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF4056454.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLGDILEL
                     RIILEIEIAKLASKRITSSEAIELKNIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEK"
     gene            7233..8492
                     /locus_tag="PC592_002500"
     CDS             7233..8492
                     /locus_tag="PC592_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HDF4056455.1"
                     /translation="MKKNKIIAFFAPAIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNRQISKHEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNESLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSAPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGILAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVIIIYLISAVFIAKK
                     HMKALSTNGKLMRYKNTFFIKKFSRKK"
     gene            8759..9325
                     /locus_tag="PC592_002501"
     CDS             8759..9325
                     /locus_tag="PC592_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4056456.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9524..10729)
                     /locus_tag="PC592_002502"
     CDS             complement(9524..10729)
                     /locus_tag="PC592_002502"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF4056457.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNASKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNDVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDDNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRNSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILGCLDKYVDDYDIIDDEELAIFVSAKSEHEIDRFLEDVKRNNYSE
                     SVKKLLKID"
     regulatory      complement(10832..10938)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11030..11398)
                     /locus_tag="PC592_002503"
     CDS             complement(11030..11398)
                     /locus_tag="PC592_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HDF4056458.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDAKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11450..12727)
                     /gene="obgE"
                     /locus_tag="PC592_002504"
     CDS             complement(11450..12727)
                     /gene="obgE"
                     /locus_tag="PC592_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDF4056459.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELESRGYTVFKMSAATRQGVDDIIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12838..13128)
                     /gene="rpmA"
                     /locus_tag="PC592_002505"
     CDS             complement(12838..13128)
                     /gene="rpmA"
                     /locus_tag="PC592_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDF4056460.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13142..13459)
                     /locus_tag="PC592_002506"
     CDS             complement(13142..13459)
                     /locus_tag="PC592_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDF4056461.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECMVKDTHIKDAQLLLNHFQLAVEEIKREYPKNIKI
                     LKK"
     gene            complement(13474..13785)
                     /gene="rplU"
                     /locus_tag="PC592_002507"
     CDS             complement(13474..13785)
                     /gene="rplU"
                     /locus_tag="PC592_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDF4056462.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13886..15307)
                     /locus_tag="PC592_002508"
     CDS             complement(13886..15307)
                     /locus_tag="PC592_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HDF4056463.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNVYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSAIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCNHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYRTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     NEVLNILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDNIEKEIMRISEHTVYKNIIVEFNDFIFEQIKGYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15325..16026)
                     /locus_tag="PC592_002509"
     CDS             complement(15325..16026)
                     /locus_tag="PC592_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HDF4056464.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPEGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKINLNTNILIPKILEIFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16028..17872)
                     /locus_tag="PC592_002510"
     CDS             complement(16028..17872)
                     /locus_tag="PC592_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HDF4056465.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18191..19384
                     /locus_tag="PC592_002511"
     CDS             18191..19384
                     /locus_tag="PC592_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF4056466.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDADVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19596..20160)
                     /locus_tag="PC592_002512"
                     /pseudo
     CDS             complement(19596..20160)
                     /locus_tag="PC592_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422542.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20361..21152)
                     /locus_tag="PC592_002513"
     CDS             complement(20361..21152)
                     /locus_tag="PC592_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056467.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLERHKSIVMWFKKVLGYISIIAFLIS
                     GFMWYYNNNLQHNMYNLGKELDGEIKQLAERHDMTKIDEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYDREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFALGLLCIIAYFILRFKISLIKNNN"
     gene            complement(21156..21485)
                     /locus_tag="PC592_002514"
     CDS             complement(21156..21485)
                     /locus_tag="PC592_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4056468.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
BASE COUNT         6950 a         3822 c         2382 g         8414 t
ORIGIN      
        1 agataaaagg agtattttat gaacatactt ggattaatag ttgaatataa cccatttcat
       61 aatggacaca tatatcattt atctaaatct atagaaaaga caaatgcaac acatactgta
      121 gcaataatga gtggaaattt tctacaaaga ggcgaaccag ctttatttga taaatacact
      181 agagcaaaaa ttgctgtcga aaatggtgtc gacttagtta tagaattacc aactttattt
      241 gcttgccaaa gtgctgaaat tttttctcat ggtgctataa caattttaaa ttcactaaac
      301 tgcataaatt ctatatgttt tggcagtgaa gaaggaaata cagaaattct ttataatata
      361 gctgaaattt tagcaaatga accaactgaa tttaagttac tcttaaaaaa atatttagat
      421 gatggtctgt tatttccaac ggctagagct aatgcacttt ttgattatat acatcaagac
      481 aaaaaaaata attttataca aaattattca aaggaacaat tatcaaagat attaaattca
      541 tcaaacaaca tactgggtat agaatatata aaaaacctca tccatttaaa cagtagtata
      601 aaaccattta ctatatccag ggttcaatca gaatataatt ctgaagaaat taagaataat
      661 atttgttctg ctactgctat aagaacttca cttaaagaaa atataaactt ttttcattta
      721 aaaaatgtta ttccagaaaa aacttataat atcttaaatg aaaaaataga taatggtttt
      781 ttacctatgt ttgatgactt gttctttgat actttaaaaa caattatact tagagatatg
      841 gacactttaa aagattattt tgaagtaaat gaaggcatag aaaacagaat ctacagggat
      901 atttttacgt ctgaattttt acatgaacta caattatcga ttaaatccaa gcgatacact
      961 ttaaccaaaa tcaaacgaac tctaaataat atattgttgg gtataaaaaa aagcgacatg
     1021 caacttataa aaaatataga tactatacct tatataagaa tacttgcttt taatgacaaa
     1081 ggaagagaag tactaaaaga gataaaaaat aaatctgaaa taaaaataat aaacaaattt
     1141 tcaaatatat cattttcatt agatgatacg atttttaaaa cactcataag ttatgatata
     1201 aaatctacaa atatatataa ttcagtatat tataaaaaca ataaagattt agtaaaaggc
     1261 cctatggatt tttatactca tccaatatat gtaaaataat tttttaaaat aactatattc
     1321 ataaaaacta ttttattaac tctttattat ataagataca ataatatcac tttatctatg
     1381 tacacatgtt tttaggatga caacatcaac ttaaatatta tgttactttc taaatttaag
     1441 taaatattgc catcctaaaa cttttaaaat ttagcttcaa atttaaaggt aaggtttaaa
     1501 atattacatt taaatctaat ttaatatttt ttgttttaca aacattatta aattaatatt
     1561 tctaatatat ttttcctggg tttaaaatat ttttagggtc aaaagctaac tttatatttt
     1621 taattaacat catataagca tctgaatttg attcatgtaa gtactctttt ttagcatatc
     1681 ctataccatg ctcaccagaa acttgaccac taagttctct agatttttta tacatatagt
     1741 caaaagtttc ttttaatctt attttccatg tattatcatc cataccatct tttaaaatat
     1801 atatgtgtag atttccatct cctgcatgac caaaactttt tattcttatt tttaatttgt
     1861 cttgaagctc gtgagtgtat cttataaact ctgctatctt atctcttgga acaacaacat
     1921 cacattcatc catttgtgtc gtagatgcct ttatagcctc taaaaatgca cctctggctg
     1981 accatataga atcatttctt tcttgtgtat ctgatataaa tacatctaat gcaccatttt
     2041 ctagacataa attagctact ttttcatatt ctttttctat atcttcagta ctatttccat
     2101 caaatgtaag taaaagataa gcatctgatg tattatctgg aaactttttc cctaaaaact
     2161 cttctgctgc cagtattaca tctctttcca taaattctat agctgttggt attgattttg
     2221 attttattat tttaggaaca gtttctattg ccattgataa atctggaaat ggtacaagta
     2281 gacttatact tttctttggt aaaggaagca attttaatat agctttagta actattccta
     2341 aagtaccttc tgaacctact aataagtcct ttatactata tccagaacta tttttaacca
     2401 cctttccacc tacatttata acttctccat ttggtagtac aacttcaaga cctcttacat
     2461 aatctcttgt aacgccatat tttactgccc tcataccacc tgcattagtg tttatattac
     2521 ctgcaattgt agcacttttt tcacctgggt caggtgggta aaataaatct ctatcttgaa
     2581 catattgacc tattgtcatc aacaaaacac ctggttctac tgtcaatgtt aaattttcat
     2641 aatcaacctc aagtatttta ttcattttac atagattaat cattattcca ccatttatgg
     2701 caacagcagc acctacaaga ccagtacctt gacctcttgg tgtgactggt atattatttt
     2761 tatatgcgta tttcattatt ttagatactt gttcagtttc aagcacattt actaaaactt
     2821 cagggtactt ctcaatccct ccaagttcat catgtgaaaa atcttcattt atatcacttc
     2881 caactaatac attttcttct ccacaagtat ctattaaaaa atctatatct tttttatcga
     2941 ctaatttata catttctatc cccctattta gctgctgatg ccatatattt ttgattatca
     3001 tctttgttat tttctatttt ttcaatcaat ttaggaataa tatcataaat atcacctatt
     3061 aaagctagat gtgctacatc aagtataggc gccttatcat ctttatttat tgctactata
     3121 tagtcagccc cctgcattcc tgcaacaaat tgaactgctc cagatacacc acaagttatt
     3181 atcagtttag gttttacagt tctaccgcta agacctattt gttttttagc atctatccag
     3241 cctgcttcta ttacaggtct tgttcctgcc acttgagcat ttaacttatt agctaactta
     3301 tacatcatct ccatatcttc ttgttttttt attgctctac ttgccacaac tatcacttct
     3361 gcttcttcca gaccaacttc tttatttttt tcttttacac ttagtacttt aattttagaa
     3421 cttaggtctt ttttttctat tttacataaa gttacctttc ctgtggcatt ctctattttt
     3481 tctggtactg aaaatatttt atatcttaca gttgcaaatt gtggtctatt attaggtgta
     3541 tttatatgag ccattatatt tccaccaaat gctggtctta tttggtctaa atcagtattt
     3601 gattgaatat caagtattgt acaatcggct gtaagacctg ttctaaatct agcagcaagt
     3661 cttggtgcta atgacctacc taatgtagtt ccaccaacta acactatcgt tggttttatt
     3721 ttatttataa agttttctat tgcttttgaa tatggttcta tcctaaaatc tttaaattca
     3781 tcttcatcat atacaaatac ttcatccaca ccataagaaa tcaaattatt acatttatct
     3841 tttatgtctt ttccaacaaa tacacaatac acaggttgtt ttatttttga tgccatctca
     3901 cgagctttac ctataagctc atatgttaca ggatgtatat ttccattatg atgttcaaca
     3961 tatactgcga ttcccctcca ttcatcttta ttaatttgta ctttactact ctctacaaat
     4021 tcaaatgcac cttttggtcc acttttgaca cacaatttac acatcttaca gccagcactt
     4081 atttctacta cacctgactt ttcttctata gctccaaaag gacatatttc taatactctc
     4141 tttaagtcag ttattttatc ttgatttaca acaatctttg acatttatta atccccctta
     4201 caccaacttt aattcctcta atttatttac aagtgcagaa cttagttcat ctgcatttcc
     4261 tcttacaata tttttatctg tattcggctt tggaggaaat attcttacaa cttgagtagg
     4321 agaaccattg agtccatagt tattttcatc tttatcttca aagtcatcta agctatatac
     4381 aggtatttct ctatctttag tatcaagttt taatttaaat gaaggtagtc ttggttgaaa
     4441 aatatctttt tctacagtta ttaaacatgg atattcaatt tcacatactt gtaaatcatt
     4501 tggcatatct atttcaacaa ctatactttc atctttagct tcaattaatt ttgtaacatt
     4561 agtaacatga ggtatatcta aaaactcagc tacttcaggt cctacctgtg ctgtatcacc
     4621 atcagtagtt tgttttccac aaattattag gtctaccttt cccatcttct taataccctg
     4681 tgatatggta taggaagtag ccaatacatc tgcccctcca aatctcctat cacttattaa
     4741 tgctccttca tcagctccca tcataaaact ttcttcaatt actttctttg cctgaggagg
     4801 acccatgcta agtactttta gattagcttt cttctcttgc tttattctaa gagctgtttc
     4861 taaagcatat aggtcatagg gattcatttt tgaatctact ccatctcttt ttagtactcc
     4921 tgtagtttca tcaacttcta ctgaagtcgt tccaggaact tgtttaatac atgtcaaaat
     4981 ttccataaag tacactcctt ttttatttaa ctataactga tactccatca ggtataacta
     5041 ctaccttgct atccttacca actatactag ttgccttttc taaagcttct ttaaaattaa
     5101 atgcatgttt catatgcatt ttttttatca tttcaggatt acacttatct gttaccatta
     5161 tcacagtata tttagataat attctcgcta gtatctgaaa ttcccattgg tctggaaccg
     5221 tatctactct atcaacactt ctaattttat ctaaaagttg ttttggagaa tctgcgtttg
     5281 ctacattttc ataaaaagat tgaccaccat gaccatcatt acatgctgca atcattatta
     5341 ttactccacc atctttgcag gtagcttcag ccgctgtcat ccctttaaca gattgataaa
     5401 tattttggtc cagtggatat ccaccatttg tagttacaac aatatcagat tttatagaat
     5461 ttacttctga tagctctgtt acaaatctac atcctttagt gtgtgctttt tcgacatcac
     5521 cagcaaaaga agcaattatt tttttatctt tatctattac aacattcaat atgaatgcta
     5581 attttgcaac tttagctgca tataccatat cctcatgaat aggattattg ttcaatttcc
     5641 cagttcttga attatcactg tctataaagt cactacaatg gttgtacatt atagtctttg
     5701 cagatgctat tcctggaagt atgctttttc tcccacctga aaaacctgca aagaaatgag
     5761 gttctataaa accttctgct attaaaagtt ctgcctcata tgctaatttg tttatatata
     5821 aatctccacc tgaaggtaat attcctactt tgcacataga tttatcatca gtagatacat
     5881 gcataactat atcttcatta tctactattt cttctcccat tttataaatt agctcttccc
     5941 ttgtacttgg cctgtgaaat ccagttgcca ctataatctt cacatcaatt tctggattaa
     6001 tcttcctaat ccttcttaat ataattggca tagttattct acttggtaca ggtcttgtat
     6061 ggtcacttgt aattatgact acattctttt tccccttaac tagttcttcc agagaattag
     6121 agcctatagg attattcata gattcttcaa ctatctcttc ttgggtctta tgttctatat
     6181 aattatccga ttttgactcc aaaacaccga gaaaacgttc atcaggtatt tctaaaatca
     6241 ttccttgttt tgaatacggt acttttaact ttaccatttt taatctccca ttataataga
     6301 ctataaaatt ggtatgtggt cataccagtt ttacatttat atgatagtac cattatctaa
     6361 tattttcaag aataatttat tttataacaa acttttattt ttcatttttt ctataatttt
     6421 tacttataaa atccatatgt tcctttgctt tctcacatgc aagttctaca tcattttcta
     6481 caactgcatt gtatatagct tcatgctgtt taagtaatat gttttcattg aaaggttctg
     6541 cgattatttt ttctcttgca tcttctataa atccatcaaa taattttgat gctgtcataa
     6601 aaagactttg aattaaataa tttttactta atgttgctag tttactgtga aatttttggt
     6661 ctaataaaac cagtactcga ttattatctt ttttattagt ttctaccctc atttcatcta
     6721 ttatattttt caattctata gcttctgaag aagttattct ctttgaagca agttttgcaa
     6781 tctcaatttc taggattatt ctaagctcta atatatctcc aagtgtacca ttattaagtt
     6841 taaaaatcat agataaaggt tctattaaag ttttttctat atttgtacat ataaaatttc
     6901 cttccccttg tctgctttct atcactccca tagtctctaa tactctaata gcttctctga
     6961 tggaagttct actcacattc atttgttcag atagttctct ttctgatagt aatttatccc
     7021 ctttttttaa ctccccattt agtattttat attgtatttg ctcaattact tgttcataaa
     7081 cttttttact agctatacta ttaaacattt ttccctccag tatgataatc gttgttgtaa
     7141 catatatcta ttatatatct taagccatta cattcatata tttttattac ttttaatata
     7201 atatcttata actcaaattt acaggtgata ttatgaaaaa aaataaaatt attgcttttt
     7261 ttgctccagc tattatagtt ggagttctag ttttagggat tatcctatac ccaaatgaag
     7321 ctataaaatc tgcaagagaa ggcttctcta tatggtctaa tgttttagtt ccatcactac
     7381 taccatttat aattggagca aacttaattg ttgatttaaa aatagtggat attatagggt
     7441 ttattatcaa tcccataact agatttgtat ttaatgtttc aggaaagagc gctttagctt
     7501 ttgctatatc tacagtatct ggttatccag taggagtaag tttagcttct gaatttagga
     7561 gtaataggca aatttctaag catgaagcac aaagactagt gtctttttgt tctacatcag
     7621 gacctttatt cataataggc tcggttggta caggtatgtt ccaaaattca aacttaggtt
     7681 atttaatgat tctttgtcat tatctaggga ctatattggt tggtcttttc tttagaaatt
     7741 atggtaatga aagtcttcca aagacgaaat tagatttaaa aacaaacata aaaaatgtaa
     7801 tcaacattag aaattcaagt gggaatggtt tttttgtttt atttggaaat gctgtattta
     7861 acggagtaaa tacattactt acagttggtg gatttgtaat tgttttttca gtggtattta
     7921 aaatactctc tctttttaat gtaatctcat taatagcatc agttatatat ttaccgcttt
     7981 catttttagg tgttagtaaa gaactctgtc aagcatttgt aagtggtcta tttgaaatta
     8041 ctataggatg taataaagta tctagtataa caagtgctcc agaaattcta agagcatctt
     8101 tagctagctt tttgatagga tttagtggat tatctattct agctcagtgt tgtacatttc
     8161 tatcaaaaac agacatagat ttaaaattat acatactaag taagtttgca catggaattt
     8221 tagctgctat ctttatattt atactttatc caattgcaaa ctctgctgta ttagtttcta
     8281 gctttgctga tacatacaac gttatataca ataatttaat ctggttttat tatcttagct
     8341 attacgatac aattcttcaa attgtaataa taatttatct aatctcagcc gtatttattg
     8401 caaaaaaaca tatgaaagct ttatctacaa atgggaaact aatgagatat aaaaatactt
     8461 ttttcatcaa gaaattttca cgaaaaaaat aaaaataata aaactttact aaatacttcc
     8521 atttttttat tatatttgtc ataattttaa taaccttttt aattagttta acaacatagt
     8581 tatttcatca caatttaata attttattag aaatattttt caaaaattct ccttaataac
     8641 atatatcaca cttgtataag tttactggca aatttttcca ttatataata tttcatttat
     8701 attatataat aaataccgac ctaaacttac caaatcaaac taagaggagt ggttgaaaat
     8761 ggcaacaaga cctatagaaa tagacgaata taaaaagata atggaactat tacatactgg
     8821 ctttacttat agtgaaaatg gcgttgaaaa aagatttaga aaaaatccta aagttgcatt
     8881 ggcactaatg ttagaagcta atttaggtct aagaatatca gatattttaa gattaaagat
     8941 aggtaatttt aaaggtaata tgttagaaat aaatgaaaaa aagacaggca aattacagta
     9001 tagaccagtt aataaaaata taattgagtc cataaatgaa catgcaagaa agtataatct
     9061 taaatcaaat gactacttag taaatataaa gacaaaagct attcagaaac agttgaggat
     9121 aatttgtaaa cacttaaatc tgtataatat aagtacacat agctttagaa agctctatgc
     9181 tactactcaa tttgaaaaga gtaacaataa tttagagttg gttaaggagc ttttaaatca
     9241 cagctctgtg gctactacac agcgatatat aagggtaact cagcaagcta ttaatgaggc
     9301 tagtgaaaat ttctttattg gttaaattat aacgtataca tttttctatt atcttattaa
     9361 ttcaccagat ataaaaaaag agtgtcttat gaactaaaaa gttcataaga cactcttttt
     9421 ttataaagtc aaatatattt tcattatttc aacactggaa aagaggctta tttctctatt
     9481 ttaaaacagc ttcttaaatt ttcataattc ctgcataaaa atattaatct atcttcaata
     9541 attttttaac cgattcacta taattatttc tttttacatc ttccaaaaat ctatcaatct
     9601 catgttctga ctttgcactt acaaaaatcg ctaattcttc atcatctata atatcataat
     9661 catctacata tttatctaaa catcctaaaa ttccatcttt attgttataa ccaccaaatc
     9721 taactactgc actacactca tcttctataa gtccacttaa atctaatttt ccttttgaaa
     9781 aagactttat atttgaattt ctattatcta ttatatctat aatatctgca taaacagcac
     9841 ttcctgttgc acctcttcca gctcccttac ctacaaaaga aagttcacct actgaatcac
     9901 ctactaaaat aactacgttg aactcattat ctatctttga aagcatatta ttatcatcta
     9961 ctaatgctgg tctaacaaat ccacttactt ctcctgattc atacttactt ctagcaacca
    10021 attttatctt acaatttaat ttttttgcat actctatatc tttttcatct attgaagtta
    10081 ttccttctaa taataaatct ttccaatata ctatttttcc ataagataaa gtagacaata
    10141 tagataactt tctagcacta tcatatccta aaacatctgc atctggatta acttctgcaa
    10201 atcccaactc ttgtgcttgt tttaaagcca catcatatgg taaattttca tcatacatct
    10261 ttgataatat aaaattacaa gtcccattta aaatagcatt tatactcttt atattattgc
    10321 cttccagtga ttctatcaat ggttttaaaa ctggaatacc acctgctaca gatgcttcaa
    10381 acttgatgct aacatcattt aagttagcta gttctataag gtcgctacct ttttcagcca
    10441 gtaaatcttt attagctgtt actacatgta tttttttatt taatgctctt gttacataat
    10501 caaaagctgg atttaatcct ccaattactt caactagtat atcaatatcc ttgtcaaata
    10561 tatcctctat atcagtagtt atcttatcaa aatacttctt atacttgtgt ttttctttat
    10621 ttttaactaa aatcccaaca acttctatat ctctttttga agcattattt tctattaaat
    10681 caattaatcc acttcctact gttccatacc ctaatattgc tatcttcact gtaacatacc
    10741 cccatcattt tgattatatt aaattattta tatatataaa tataccaatt aaaaaagctt
    10801 gagtataaac tcaagccata tgacgggttt atactcatct ttcagcataa atgctgcagg
    10861 atttagcacc aatgtataat taaatatact ggttgccggg cttcacaggg ccagtccctc
    10921 tgccactctt gataagattg ctaatttaaa tttatgttta atagtataat acaatttctc
    10981 ccaattgtca ctattttttt aacttatttc tttaaaagga tataaactat tatctaacag
    11041 ctcttttagt tggtttaccc ttttttgtaa cattattatt tttagtcttt gctttcgcct
    11101 gttcatgtcc tggaaaaagt attttaggct cttcaatgtt tctcttgtaa atagtaaatt
    11161 taaaaccaat agcctgcaca aattcagctc ttaaagcttc acatactgca ttagcagttt
    11221 ctttagcatc aagacctgca ttttctaata tagtaacttt taccaattcc ctagttctta
    11281 acataccatc taattgctct aagaagctct ctgtaacacc ttctttacca atttgtgtag
    11341 taggctttaa agtatttgcc aaagatctta aatacgccct ttgtttccct tttaacatat
    11401 tctcacctct ataattctat acttaaatta tctgtaatct atatttaaat taattgtaaa
    11461 actcaaattc taattcataa attttaacta catctccatc ttctattccc atttctctaa
    11521 gcctgtcaaa aacaccttga ctctccatag ctttttggaa atattgaagt gattccatat
    11581 catcaaaatt tacagaatac attattcttc taagtgcttt acctgtaact acatacacac
    11641 catcttcaat atctatactt agctcttctt cagttccaat atcaagttct ggtctataca
    11701 tttcttcttc tgaaaccagc tccacatctt ctacttcttt tagcatttta gaaacatatg
    11761 ctattatatc atctacgcct tgacgagttg ctgctgacat tttaaatact gtatatcctc
    11821 tgctttctaa ttcactctta aacttctcaa acttactttc atcttctaat atatcaaatt
    11881 tatttgcaac tacaacttgt ggtctctttg aaagcttttc attgtacaat ttaagctcat
    11941 catttatctt gtcaaaatct tcaatagggt ctcttccttc taacccagat atatctacaa
    12001 tatgtatcaa tacctttgtt ctctcaacat gtcttaaaaa ctcatgacct aatcctatgc
    12061 cttcagaagc accctctata attccaggta tatctgcaag tacaaaacta tctccaaact
    12121 tagtttgaac aacacctaga tttggtgtaa gtgttgtaaa atgatagttt gcaatttttg
    12181 gtttagcttt agttacaact gatagaaatg ttgatttgcc tacatttgga aatcctaaaa
    12241 gaccgacatc tgctatcatt ttaagttcaa gagttatcca tctttcttct ccatctgtac
    12301 cagattttgc aaaagctgga gcttgcctta ctgcatttgc aaagtgttga ttacctttac
    12361 cacctatacc acctttggca actatagctg tatctccttc tttttttaaa tctgctagta
    12421 caagacctgt agcctcatct cttattactg tacctgctgg tacttttaat actaaatttt
    12481 ctccattttt accagctctc ttacctttgc ttccgtcgcc accattttga gcttgatatt
    12541 ttttctggta cttaaagtcc attagagttc taagacctaa atcaacttca aatatgatgc
    12601 ttgctccacg accaccatct ccaccatctg gaccaccagc tggaacgtat ttttctcttc
    12661 taaatgctac cgaaccattt ccaccatttc cagccttaac aaatattctt gccttatcta
    12721 taaacaaatt cttcacctac ttaattaaaa acttttaatt agcattacca aaaataccat
    12781 tataaattca tcagtattat aagaaaaagg agtgcctcaa cactcctttt atgtatatta
    12841 ctcagctatt gctactggat atatactaac tttttttctc ttcttgtctt ttctttcgaa
    12901 tttaacagta ccatcaacta atgcaaataa agtatcatcg ctaccttttc caacattagt
    12961 tcctggatgt attttagttc ctctttgtct aactattata cttccagcag ttactaattg
    13021 accatcgaat ctcttaacac ctaatctttt agatatagaa tctctaccat ttttagaaga
    13081 acctacccct tttttagatg ctaataattg taaattcatg tttaacatat ggagtcaccc
    13141 cctacttttt taaaattttt atattttttg ggtattcccg tttaatttct tcaaccgcta
    13201 attgaaaatg atttagtaat aattgtgcgt cttttatatg cgtatcttta accatacact
    13261 ctatatgacc ctcttctcct actacttttt caaattcaat cttttgtaat ttgtctaaag
    13321 aatttataac tgcaatagca ttagatgtaa ctgcagcaca tactatatca tagcctattt
    13381 cagcaaaatc agcatgtccc tttaaacaaa aaccttgtaa caagaaatca tcattataat
    13441 aatatttaac ctttatcata acttaaccaa ttactaagcg tttatttttt ctacaactat
    13501 cttagtgtat gattgacgat gtccttgttt tcttctgtaa tctttttttg ctttatactt
    13561 gaaaactata actttcttag ctttaccttg ttcaacaact ttagcttgaa cagatgctcc
    13621 ttctactact ggagaaccta attttaattc tccatcttta gagcaagcta atacttcgtt
    13681 taaagtaaca acatcacctg cgttagcttc taatttttca acgaataata catcaccttc
    13741 agaaacttta tattgctttc caccagtctt tactatagcg tacattaaat acacctcctc
    13801 ggcctcaaac tcgccagtac aaggtacttc atttgaagat ttaaaccttt actgtgcggc
    13861 attacaatta ttaattataa aatatttaca ttttattgtc aactatttta tcgaaaataa
    13921 cattggtttt attgtgcttt aatgtactat ttgcgtttaa agaaatcttt atattatatt
    13981 tttcaccaat tttatcaatt atatccatat aatatccttt tatttgttca aaaataaaat
    14041 cattaaactc tactattata tttttgtaaa cagtgtgctc acttattctc ataatttctt
    14101 tttcaatatt atctagtata taatgtacag attttattgt ttgttcacca tcacaacatg
    14161 gacaagacat taaataatac ttatcaatgg attctttttc tctacgccta gcaacttcta
    14221 ctaaaccaag ctttgtcata cctaatactt cagcttttct tttatcttta ttaaattctt
    14281 cttctaggat gtttaaaact tcattttgat gcttcttttt atgcatgtcg ataaaatcaa
    14341 ttattattat tccagctata tctctaattc taagttgcct tacaatttct tttgcagcct
    14401 caagattcgt tctataaacg gtttcgtcaa gtttaccagt tccaataaac ttacctgtat
    14461 ttacatctat aactgtaaga gcttctgttt tttcaattat taaataacct ccactcttta
    14521 accatacttt tttatttaat aatttttcta ttttagattc tattctgtat aaatcaaata
    14581 catctctatt ttcctcaaga cacagtttat caacataagt cttatctata cctcttaaaa
    14641 tagacttaag ttcagagtac ttatcgtaac tattggtaat tatagattca atatcatcat
    14701 tcacattatc ttttacgtat ttagttgcaa aatctaaaga cttatataat aatttcggac
    14761 ctataccaag tttatattct tttaaaatgt tttcatactt taattttaac tcttctatat
    14821 ctttctttat ttcatcatga ttacaacctt gagcctcagt tcttattatt aatcctagat
    14881 tttccttatt tactgcctta gtaatttttt ttaatctaaa tcgctctttt tcatcagtaa
    14941 ttttatttga tattgtagtt ctatcattgg aaggtatata gacaatatac cttccagaaa
    15001 tactaatctc agtgtttaat tttgcacctt tagttcctat ttcttcttta tttatctgaa
    15061 ccaaaatatc ctgaccagac tttatagcac ttcccttttt taattgtaaa taagcaagtt
    15121 tcttaaatcc aatatctaca aaacaagctt ctattcctgg tataactttt tttacgattc
    15181 cacgatatac attggataca gtcttcttat ttaaattgtc ttcaacaaaa agttctgtta
    15241 atctttcatc ttcaagtact gctgttttct gagaccctat tagggactca ataactatct
    15301 ttttcacaac ttcacctctc gagcttacat aggagtcact aattccccat cttctaatac
    15361 atataaatct cttctcaata tatcaacatc taatgggtca atatcaagtt caaatatctc
    15421 taatatcttt ggtataagta tattagtatt taaattaatt tttgagcctg tagctatagt
    15481 agcagtaaga gtaatatgtt catcttctaa atttaaaaca tcaaaggttc ttatcatggg
    15541 tcttatatct acttcaacca tcttaccttt tttattcttt tttgttatga ttatttcttt
    15601 attattcata aagtcaatta cttttctttt tacaaactct ttggtcatag gtcttttcaa
    15661 atctatatta aacaaatatt ctccataatc tataacagaa gaaagagaag gtgtttgtct
    15721 atcaatttct tttgctttga taaaatctat cccctctgga agttggattg atactttatt
    15781 taaaaattcc tctactgata aatcatcttc ttctatctca atatctacat actcaccctg
    15841 actttctgtt cctaaagcca aagcattacc ataactcatc ttagggtgag gattaaatcc
    15901 ttgagaatgt gataagttta tttcagctct tctaaatgct ctttgtaata atctctgaag
    15961 gtcaagatgt gatatatata tcatatcgcc ttccttttta aattttactc ttattatctt
    16021 actcatatta gcaaagcccc cttcctatat catgtatatt tattccacag ccattgcagt
    16081 tatgtctaca atcagaagtg attttttctt ttttagcatt ttcatcttct ctaattaaga
    16141 attttttact aatacctaca tctatatggt cccaaggaaa tacctcttca taatttctat
    16201 ttctatgtgc ataaaaatct atagaaagat tattcttttc catagcttct ttccatatat
    16261 ctaaattaaa gtgctctgcc catccatcaa atttagcgcc tagtctaaac gcatcatata
    16321 tcacttttcc tattcttcta tctcctctag ctactactgc ttccatcaaa ctagtctttg
    16381 aatcatggta attgtatttt atattgttgt ttcttaattt atttactaaa tgtctttgct
    16441 tattaatcac ttcttctgta gtgtcttgac catgccattg aaaaggtgta aatggctttg
    16501 gtacaaatgt agaagtactc actgtaacac taaaacttct ctttagcttt cctccattta
    16561 cttttctata aatatcaata actttataag ctaatttagc tataccatct aaatcttcat
    16621 aagtctcagt tggtaaacca atcataaaat acaacttaac actattccat cccatctcaa
    16681 aagctctttc tgttgcattt tccaaatctt cttccgtaac acctttattt ataacatctc
    16741 taagtctttg agttcctgct tctggagcaa aagtaagccc agactttctt acttgctgta
    16801 ttttgtcagc aatttccatt gagaagttat ctaatctaag ggatggaagt gaaataccaa
    16861 tattattaga tgcatattca tccaccaaat aatcagtaag ctctgataac ttactataat
    16921 cactcgtact aagtgatgat aatgatattt catcatatcc agtattctta actaatttat
    16981 ccaatatttc tttaagtctt ttgacactct tttctcttat tggtctgtat atcatacctg
    17041 cttgacagaa tctacatcct ctagtgcatc ctctaaataa ttctagtact attctatcat
    17101 gaacagtatc tatataaggt actattagtt tttctggata atctacagtc tcaacatctt
    17161 ttattatcct tttagtagga tttttagtaa tcccttccct gttaggagtt acactttgaa
    17221 ctgtaccatc ttcattgtac ttgacatcat aaaaacttgg tatgtatact ccttctatac
    17281 tagatatttt atataaaaaa tcttctctag tcgttttatt tttcttccat tctttatact
    17341 catttactac ttctaaatta acttcttcac cttcacctaa tattactaca tctacaaaat
    17401 ctgctaaggg ttcagaatta taagcacaag gaccaccaac cattataaat gggtcttcca
    17461 aagttctttc ttcttttaat attggtatat tggctaaatc taatatattt aatatattag
    17521 tatatgaaag ttcatattga agtgtaaaag taacaaaatc aaagtttgtt ataggctctc
    17581 ttgactctaa tgcaaataat ggtatacttt tttctctcat tatattttcc atatcaactg
    17641 caggagaata cactctctca caaaatacat cttcatcctt atttattaca tcatataata
    17701 tatgactccc taagtgactc ataccaactt catataaatc tggaaagcaa tgtgcatatc
    17761 ttatcaattc actattacta gtatctttat gaattgaatt tatttcattt ccaagatatc
    17821 tagcaggctt ttctactttt tttaagattt ttttcaagtc tactttattc atttattaaa
    17881 actcctccaa acaagctctt tatttttatt cttatttata agtaatatta tacacgataa
    17941 aatattttct atcaaaaata taactaaaat attgaattta aaatacatat tattcacaaa
    18001 atagaatagt taaaaatatt taagaatatt ttctattaaa tttttattga aatacaaatt
    18061 ttttacaaag tatgatatat tataaacata aagctattgt tttacattac ttatcatgac
    18121 atctcttgtt ttattcacct taaaatgggg tatgttactt atataatgat aaattttagg
    18181 agggttaaaa atgagtaaag tttttgaagt aaaaaaagat atctacttta ctggcgtagt
    18241 agatgaaggt ttaaaagtat tcgacataat aatggaaact gagtttggga caacttacaa
    18301 ctcttattta atcaaggacg aaaaaacggt tttatttgac acggtaaagg caaattttaa
    18361 agatgagttt ttaagtaatt tatcagaagt tactgatata gctaaaattg actatgttgt
    18421 aattcatcat acagaaccag accatgcagg tagtttaaaa tacttattag atataaatcc
    18481 taatatagaa gtttattgta ctaaagctgc taaactatac ttagatggtc aaataaatag
    18541 accttttaac tgtcatgtaa taaaagatgg tgaaatttta aatattggta aaagaaatct
    18601 tagatttata actgctccat tcttacattg ggttgataca atgtttactt acattgagga
    18661 ggacaagact cttttaactt gtgatgcatt tggttgtcac tttgcaagtg ttgatgcaga
    18721 tgtagtaaat agcgaagatt acctaaaatc agctaaacac tactatgatt gtatagttaa
    18781 gccatttgct aaacatgttt taagtgctgt agataaggtg gtaggactaa acatagaatt
    18841 tgatactata ttgacttctc atggtccaat gcttactaaa gacccaatgg ctgctgttaa
    18901 aagatatgtt gagtggtcta cagaagcggt taatacaact aatcaaaatc aagtttctat
    18961 attctactta tcagcttata gcaatacttt agagatggct aaaaagataa aagaagggct
    19021 tgataaagaa ggtgcaaagg ctgaattata tgatttagaa gatatgacat taacagaaat
    19081 gcacgataca ctagtagtat caaaagtaat attattaggt tctccaacta taaacaaaac
    19141 tatggttaaa cctatgtggg atttattctc tgttatagac ccaatggcta accaaggtaa
    19201 gatagcagga gtatttggtt catttggttg gagtggtgaa ggtataacta tggctgagac
    19261 tttacttaaa tctatgtcat tcaaaatgcc tgtagaatct cttaagaaaa aattcttccc
    19321 tagtgaagag acattaaaag agtgtatggc atttggtgca gaatttgcaa aattagttaa
    19381 atagccatta atcacacata ctattattta aaataaatga ttttatattt aaaaataaat
    19441 taaaatggag ttgtctcaaa attaattttt ctaatctaat tttaagttca actccttttt
    19501 tattttccaa aatgactaat ataatgataa atgcaccctc accaagaggg tgcattgttt
    19561 ataatctgtt ctatttgtat actagtataa ttgtattaat tcacgtatct agcatatcct
    19621 acttgcccta ttccagaatt agatgttgtt tcaccaactt ctactttaat aattacatta
    19681 ttttctttac acttttttaa taattctgtt gtagaaaggt tcttagcagt aaaatctaaa
    19741 gaaaaggggt tatcatattc aaaaggataa ctaacaggtt caccatctgg agctaatgca
    19801 accataccat atggtatatt tataaaccct attacagaaa ttgtatgctt tgatgggtct
    19861 aaatttgaat ttttgcttat aaactccctc tgctgcgttc cagttaacat atgttgtgtt
    19921 gtttttaatg tgattgtaag caactctaat cttagcatct gtggtcatgt tctttgtaac
    19981 tttcttattc ataaagtctg cttttgcttg tgatactgaa ttaagttgag cttataacaa
    20041 ctttggagca tatatactgt tggtttcagc tacatagctt ttcggtgtct ttgcagtatt
    20101 gtcaataata catttaaaat taaagttgta tacacttcat acattctccc ctaacaacat
    20161 tatacagatt ataatttgta tattcagtac attttttgaa aagtataatt atatcaaaat
    20221 atgtgattat gtatagatac aatccactat ggaaaaatat ataataaaag agtataacaa
    20281 acaataaaaa ataagatgat tcaaatttta ttttgaaaca tcttatttac tctacaaatt
    20341 aaaattactt ggtgaattat ttaattatta ttttttatta aagaaatttt aaatcttaat
    20401 ataaaatatg ctattataca taataatcca agtgcaaatg ctactggaat taacatctcc
    20461 gattcaaagt aaaagaaata ttctaagaaa atatctggat ttactatatt cccattcttg
    20521 tctaaaaaat ctttcccatt atatcctaag tgctgtataa aattacttat gttattataa
    20581 tctgcttccc tatcatacac catattagca ttcaatccag aagaacttaa attagtgttt
    20641 ccatctttca tatctattac atataatcta agagctttga ctttactata cttatcttta
    20701 tcaagtattt tttcaagttc taacttatat tcatcaatct ttgtcatatc atgcctttct
    20761 gctaattgct ttatttctcc atcaagttct tttcctaaat tatacatatt atgttgtaaa
    20821 ttattattgt aataccacat aaatccagaa attaaaaatg caattatact tatgtaacct
    20881 aatacttttt taaaccacat tacaatggat ttatgcctct ccaatgataa agatagttct
    20941 tttattatat tacataattc atactgcatt tcatcaccat catcaaatct ttcaattgct
    21001 tttttacatg cttcttcttc atctaatcct tctaatttaa attcatttgc agattctata
    21061 agatggcatc tcatttcctg ttttaattct atagtacttt tattgtcaca ttttttatac
    21121 agtttatcta aatattcatc tattagtttc atgaattaat ccacctctcc caaaaattga
    21181 ttcataacct ttttaataaa tctccattct tgtttcttta tttctagaaa atctttacct
    21241 tcattagtta aattataata ttttcttctt ccacctgaac tttgttcatt gctataataa
    21301 gatttaatta aatttttaga ttccattctt ttaagtgcaa gatacattgt tccttctttt
    21361 aattcaaact cacttctttc tcttacttgc tttgcaattt catatccata acaatctttc
    21421 ttttctaata tagaaacaat taatatatcg atataacctt ttaacacttc tttatttaac
    21481 tgcattatgt accaccgcct tttcacctac tactctataa tgtatagtaa ttatatttac
    21541 tataataata catagtacta tataatac
//
LOCUS       DAMKOJ010000060        21031 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000060 DAMKOJ010000000
VERSION     DAMKOJ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21031
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.064"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            93..839
                     /locus_tag="PC592_002515"
                     /pseudo
     CDS             93..839
                     /locus_tag="PC592_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            875..1288
                     /locus_tag="PC592_002516"
     CDS             875..1288
                     /locus_tag="PC592_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4056469.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIQARKELLIEQRNQLAKRMEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEEVSYE"
     gene            1281..1820
                     /locus_tag="PC592_002517"
     CDS             1281..1820
                     /locus_tag="PC592_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4056470.1"
                     /translation="MSKHVLIVSASPRKGGNSDLLCDQFTQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYKKEASCPQKDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVSAADENIADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNI
                     GDIKGSEAMKQAYEMGKMA"
     gene            complement(2010..2495)
                     /locus_tag="PC592_002518"
     CDS             complement(2010..2495)
                     /locus_tag="PC592_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056471.1"
                     /translation="MNKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEKCSKTIKNSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEIDWKNLEKLITKENNIMQES
                     V"
     gene            3347..3724
                     /locus_tag="PC592_002519"
     CDS             3347..3724
                     /locus_tag="PC592_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF4056472.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            4124..5932
                     /locus_tag="PC592_002520"
     CDS             4124..5932
                     /locus_tag="PC592_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4056473.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEVSKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHVKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNICKNKDINIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQS"
     gene            6415..7629
                     /gene="dpaL"
                     /locus_tag="PC592_002521"
     CDS             6415..7629
                     /gene="dpaL"
                     /locus_tag="PC592_002521"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF4056474.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLRDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSDEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGAEASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            7874..9061
                     /locus_tag="PC592_002522"
     CDS             7874..9061
                     /locus_tag="PC592_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDF4056475.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            9077..10660
                     /locus_tag="PC592_002523"
     CDS             9077..10660
                     /locus_tag="PC592_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF4056476.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDDNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDVIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIRDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            10688..12016
                     /gene="ssnA"
                     /locus_tag="PC592_002524"
     CDS             10688..12016
                     /gene="ssnA"
                     /locus_tag="PC592_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDF4056477.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTNEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISSEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            12161..13513
                     /locus_tag="PC592_002525"
     CDS             12161..13513
                     /locus_tag="PC592_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF4056478.1"
                     /translation="MSQDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLRFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVILNIFFNELGSKKEKNNKVEEAK
                     "
     gene            13703..14812
                     /locus_tag="PC592_002526"
     CDS             13703..14812
                     /locus_tag="PC592_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4056479.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKKTGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMTARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            15091..16482
                     /gene="hydA"
                     /locus_tag="PC592_002527"
     CDS             15091..16482
                     /gene="hydA"
                     /locus_tag="PC592_002527"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF4056480.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGATKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     EGLEEWHEKAKDKCYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKAENNLSPKYHQLTRPAILEAE
                     ATSRLMKIAEVANSKVYVVHLSCRESLEEVLKAKQRGVDVIVETCPQYLLLNDGLYDL
                     DGFESAKYVMSPPLRDKENNEILWNAISDNQIDTIGTDHCSFNYRGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGAIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            16476..19037
                     /gene="xdh"
                     /locus_tag="PC592_002528"
     CDS             16476..19037
                     /gene="xdh"
                     /locus_tag="PC592_002528"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HDF4056481.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVREHLVRGNAEEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAIAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     VTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASSKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVMLDENGRLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVKSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            19189..20535
                     /gene="rpoN"
                     /locus_tag="PC592_002529"
     CDS             19189..20535
                     /gene="rpoN"
                     /locus_tag="PC592_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDF4056482.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         8444 a         2356 c         4055 g         6176 t
ORIGIN      
        1 ggggatagcc tgtggagaat tagtaagaca tattttagta tgcaaaattc tgtgaagcag
       61 gaaccctgtg actttagtca tgggaggttc agagctttaa gtttattgaa gaaaagaaaa
      121 aggaaggaaa aataaagaat attggttttt cttttcatga tagtgcagaa ttattggata
      181 aagtcttaag tgagcatcca gaagtagact tcgtgcaatt acagattaat tatttagact
      241 gggataatga aagcatacaa tctagaaaat gctacgaggt ggcacagaag cataataaac
      301 ctgtaattgt tatggagcca gtaaaaggag gtacacttgc aaaaatacca gaaaaagcag
      361 agaaattatt gaatgactac aattcagata tgtcaattcc atcttgggca atacgttttg
      421 cagcaagtaa agataatgtt atgatggtct taagtgggat gtcaaatatg gaacaattat
      481 tagacaacac aggatatatg caaaatttca aaccattcat acaagaggaa tataatatta
      541 tagatgaagc agtagggatt atcaacgaat caattttagt tccttgtact gcatgtcagt
      601 attgtgtaga aggctgtcca aaaaatatcg ctattccaaa ctattttgca ttgtacaatg
      661 cagaaaaaca agctcttaat actggatttt caacacagat ggtttactat aataattata
      721 ctaaaactta tggaaaggct tcagattgca ttgaatgtaa acaatgtgaa gaaagttgcc
      781 cacaacacat taaaattata gatgctttaa aaaatgtagc agaaatcttt gagaaataat
      841 tcaatctata caatatcaag aggggaagat atatatgaca atttcagaag ttagtaaaaa
      901 atacgaactt tcagcagata ctttacgata ttatgaacga attggtttga taccacctgt
      961 aaatagaaat aaaagtggaa ttaggtcttt tacagaagaa gattgtgagt gggttaattt
     1021 cataaagtgt atgagaggtg caggtctttc tattgagaca ttgattgagt atgtagctat
     1081 gtttcaacaa gggagtagca ctatacaagc tagaaaagaa cttttaatag agcagagaaa
     1141 tcaactagca aaaagaatgg aagaaatgca aaaaactttg gaacgattaa attttaagat
     1201 tgatagatac gaagaaggaa ttattgagaa agaaaaagta ttaaagagca gtagaaataa
     1261 gaaaatggag gaagtatctt atgagtaaac atgtattgat agtatcagct agtcctagaa
     1321 aaggtggaaa ttctgattta ttgtgtgacc agtttacaca aggggtatta gaatctaaaa
     1381 atcaagtgga gaagatattt ttaaaagata aagatattaa ctattgtact ggatgtggtg
     1441 cttgttataa aaaagaggca agttgcccac agaaagatga tatgggagaa atccttgaaa
     1501 aaatgattga ggcagatgtg attgttttag caactccagt ttatttttat actatgaatg
     1561 cacaaatgaa aactatgatt gatagaactt gttctagata tactgaaata tgtgataaag
     1621 atttctattt tatcgtttca gcagcggatg aaaatatagc tgatatggaa agaacaatag
     1681 aaggatttag aggatttaca tcatgtttaa atggttccaa ggaaaaaggt atagtatatg
     1741 gtgtaggggc ttggaatata ggtgatatta agggaagtga ggcaatgaaa caggcatatg
     1801 aaatgggtaa aatggcatag tatatttgta taaaatagaa tatattttta tcatttcaac
     1861 aataaaaaag aggcttatct ccattttgag acagcctctt tatgttatat catttatttt
     1921 tattctgtat ccttttatat cttctatttt ttgatgtcta tttaagtatc tgttgttact
     1981 catatatttt aataattacc cttaaaaaac tatacagatt cctgcataat attattctct
     2041 ttagtaatta atttttctag gtttttccaa tcaatttctt ccatatttgc aaaataatga
     2101 ccacttccta tgcaagttag gtaagacttt ccatctaatt caaacgaaga accaccaata
     2161 cactttgaat tacatttttt acaagtacga gttttagtta tgctattttt aatagtttta
     2221 gagcatttct ccacagcatc cttatacgta tttaaatgaa aaagatttgc tttaactctc
     2281 catttctttt cattacattc aatagtaaat aagctacgtt ttggcttctt agttgaatat
     2341 actattttgt aagaacgagc acctgtcttt ggttcaattt tacaatctaa tgatttacca
     2401 agttcgtgta aatgacatgc aatatcataa tctttaccac ttagtacttc taacatttct
     2461 tctgttgtct ctgctgttaa ttcacttttg ttcatattaa aaaattcccc ctatataaat
     2521 aataatttca tataaaaata attaatatca gtatattaaa tgaaattatt aaaatcaata
     2581 gaattactat aatcttacat tattgggcat agaatgagag ctaatgattt atcagaaata
     2641 agacttaata gtatgaaaat ttacttagac gtggtacaat tctataaaag atttaaaact
     2701 aggaaaggag aaagttgttg agatatagcc aatataacaa tttatttata gattgcaaat
     2761 ttattatgag attaattaga ttgttaagta agactattaa aaggtagttt ttgggattct
     2821 cagcaacagt ggtaggatat tgataatttt ttggttacta ttatatttag ctattatatt
     2881 ttcgataggt tctatgataa ctagggtaaa taaggtatgg gtaaaggttt tattatttgt
     2941 aatagtggga ttgtcaacta tagttctttc atatgtaata acttgataat tttagagtaa
     3001 aaaacaactt taatctggaa attctcaaaa caagaattct catgttggta aatttctaga
     3061 tatgagaaaa aatttgacat tataaaaaag taattttaaa gcattttttt acgaaaaaat
     3121 tcagaagcaa ctattttgaa tgacttcaca aaattttata tataaatgaa gtttggcatg
     3181 ttaattgctt taataaaagt taacaagaca caaataaata taatcatcta agtattgatt
     3241 atttgaagtt ttagatttga aatttaatct aaaagttcgt attaatattg gtgtttagga
     3301 aattttattt tcctgtaaat ataacttaat aataggaggt gaagtcatgt caaaagtagt
     3361 aatagctaca gagaaagctc caggagcaat tggaccatat tctcaagcaa ttcaagttgg
     3421 aaacatagtt tctacatcag gtcaacttcc aatagatatg aagactggcg agttagtatc
     3481 tgacccaaaa gaagcaacaa aagcttcttt agataatgta aaagcaatat tagaacaagc
     3541 tggtacaagt atggataaaa tatttaagac tacagtattc gtaaaagatt taaaggattt
     3601 taatgatatt aatgaagtgt atgctacata ttttaaagaa aatccaccag caaggtcatg
     3661 tgtacaagtt gctcaattac caaaagatgc agttttagaa attgaagcaa tggcagtatt
     3721 ataagtatta taacaataaa accaataaca aaactaatga aaattaaaaa ctaataaaaa
     3781 aagtctacaa ttaaaaaagt ttatattaaa aaagtctata taaaaatcta tctaaatatt
     3841 taactattga gcttttctca tataatgtat atttttatgt taaaaatata tttgttatac
     3901 gaggaaagct ttttttattt tattattgta ttgtgattta ttttattgtc tgcatattat
     3961 aattaagatt actatataaa acaaactttt tataaattaa tatcatgtgt tttagcgcaa
     4021 atatataaat aagtaatgtt ttatatatat tttaaagagt gactatatgt taaaatatag
     4081 ctaaactgat aatttggtaa attaaattct aatgggggaa actatgttaa gtaaattaaa
     4141 agaatttcaa caagaaatga taaaatacac tgaaacagta gcgagtgtgt tagatgtaga
     4201 tattgaaata gttgatgata gattaataag aattagtggc acaggtctgt ataaatcaaa
     4261 gataaatgaa agcgttgtta cagaaggctt tatttacgac aatgttatac agacaggtca
     4321 ggaattagtc gtattggata tatgtgataa tcagctttgt atagaatgtt cccattacat
     4381 gaaatgccta aataaagtaa taatagcagt tccaataaag tataataatc gaactatagg
     4441 agtaattggt gctattagta cagataaaac taaaaaagta gaaataagtg caaaaataga
     4501 taattattta aaatttgtca atcatatatg cgatttaatt tctatgaaaa tagaagaaca
     4561 tgaagtgtca aaaaatagca gtagaaaaat ggatatgatg atagaaatca ttgaaaatgt
     4621 tgaaaaaggc gttataatac tagacataaa tagcaaaata tcttatataa acaatatagc
     4681 tctaaaaaaa ttagatatag ataaaaatat aatagaaaat atagtaaata tagtatctgt
     4741 tgaatcttcc tcaaatggac atgaattact agaaattgat attgataaca agatttataa
     4801 tataaatgcc aaaataattc cagtatatcc atatataaat caatacgaca aaataataat
     4861 atttgataag acatatatca atcataaagg acatgtaaaa gttaatagtg gctggggaaa
     4921 tagtgatata gagtctataa ttggaaattc agaagcaatg ttaaaagtaa aagagagaac
     4981 taagaaatta gcaaagtcaa attcaactgt acttataact ggggaaagtg gcacgggtaa
     5041 agaactaatt gctagagcta tacacgctga gggtagtaga tggaataagc catttattgc
     5101 gataaactgc gctgctattc cagaaaatct ccttgaaagt gagctatttg gctatataaa
     5161 aggtgcattt agtggagcta gtagtggagg taaagtaggt aaatttgaac ttgcaaatga
     5221 aggtgttata tttcttgatg aaataggaga tttatcaatg cctttacaag caaagttact
     5281 tagagttttg caagagagaa aatttgcgag aattgggtca aataaactta tagatttaga
     5341 tataagagtg attgctgcta caaataaaaa tttattgaaa ttagtaaatg aaggtaagtt
     5401 tagggatgat ttatactata gattaaatgt aattcctata aatttgccac ctcttaggga
     5461 aagaaaggat gatattgagg caataatgat gaagtttgct tctaaatatt ctttagagtt
     5521 aggtattcag ttaaataaaa tagaagaaaa tgtaatgaat atgttgatta actataattg
     5581 gccgggaaat ataagggaac tggaaaatgc agttgaatat atgatgaatt tggttggaga
     5641 tgatggaata atatataaag atatgcttcc attggatatt ttaaattatt ataatattaa
     5701 tggaaacatt tgtaaaaata aggatataaa tataatattt gaagatgaca tagttggagg
     5761 aatagtagag aatcaagaaa ggatactttc aattaaagaa ttagagttga cttacataaa
     5821 taagctgttg aataagtatg gaagagatac gaagacgaag aagaaaatag caaaagactt
     5881 aggtataggt ttagctacat tatataggaa gttggaagaa gaacagtcgt aatataatag
     5941 aaaattaaaa ccataaatct ttatatattt taaaactaaa taaaatacac atataattaa
     6001 aatagaaata aaacataaac ttagaactaa ataaaatata atcaaataaa attacagaag
     6061 gttatagtca tatatttata gaaaataaaa gtagtaatat atctgataaa acaatagaca
     6121 tataaaaaat aagagcataa taaaggaaaa attaagacaa ataaacgatt tctcgaattg
     6181 ataattctcg tattgataaa aatttcccaa tatgagaatt ttttctttta taaatcttgt
     6241 tttttgcact caaaacttat aaactttaaa gaaattttat aaaagtatgt aattccaaca
     6301 taaaaaaatt gtttttagaa taaataatat tggcatgcta attgctttac tataagacac
     6361 aaagataaaa aattaaaatg acatcgaaaa atttgaaagg ggaatataaa ataaatgaga
     6421 gaaataaaat ggaaattaaa taacttacct aaatcagagg aaaaagaaaa aggaattgaa
     6481 tttttaagag atgaagagat tgcaaaggct aaagcttttc atgagagctt tccacaatac
     6541 gaaaagactc ctttagttaa attagataac ttagcaaaat cactaggcgt aagcggaata
     6601 tatgttaaag acgaatctta tagatttggt ttaaacgcat ttaaagtttt aggtggttct
     6661 tactctatgg gtagatacct agctcaaaga ttagatacag acatatctga gctaggttat
     6721 gataaattaa cttcagatga aataaaagaa aagttaggag aaataacttt ctttacagct
     6781 acagatggaa atcatggtag aggagttgct tggacagcta ataaattagg tcaaaaatct
     6841 gttgtattaa tgccaaaagg ttcttctgaa tttagattaa ataaaatcaa aggagaaggt
     6901 gcagaagcta gtataacaga cttaaactat gatgatgcag taagattagc taatgattat
     6961 gcagaagctg atgaccatgg agtaatggtt caagatacag catgggacgg atatgaagaa
     7021 ataccagcat ggataatgca aggatatgga actatggcta aagaagctat agagcagtta
     7081 aaagaatatg gagtagatag accaacacac gtatttgttc aagcaggagt tggttcactt
     7141 gctggtgcag ttcaagggta tgttgcttca atatatgatg aatgcccaat aacagtagta
     7201 gtagaggctg atgaggctga ttgctactat aaatcagcag aagctggaga tggaaaacca
     7261 agatttgttg gaggagatat gccaactata atggcagggc ttgcttgtgg agaaccaaac
     7321 actataggtt ttgaagtgtt aaaaaattat tcatcagcat tcgtttcagc accagactgg
     7381 gtatctgcta aaggtatgag aatattagga aaccctctaa gaggagatga gaaagtaatc
     7441 tctggagaat ctggagcagt tacaactgga gcattagttt caatccttga aagtgaagat
     7501 ttaaaagact taagagaagc tttgaaacta gatgagaact ctaaagtatt attaataagt
     7561 acagaaggag atactgaccc tgataaatat agagatatag tttggaatgg tgaatgccaa
     7621 agtaaataaa agacttaagg aaaagaaaca tttaacaaat aaaagaaaaa tttaagcaaa
     7681 tgaaaaacta aagcaaatga aaaattcaaa ataaaaacta aataaaatta aaataaagtc
     7741 taaataaaaa tttaataaat aaaatataaa ggaataaaaa atcaatagat taagtgaaat
     7801 gctaataaat taaaaaagtg aaatatcaaa ataaaacgtc aacaaattaa aaattatatg
     7861 ggggaatatc aaaatgttaa atgaaacaag aaaaaaacaa ttaactgaag tatgccaaga
     7921 cttaataaga aatgctagtt attcaggtca agaagaaaac gtagtaaaag ctatagaaga
     7981 gaattttgct ttactaggtt ttgatagttg gtcaagagat agatatggaa atatagtagg
     8041 atgtataaaa ggaaataaac caggtaaaaa aatattattt gacgggcata tagatacagt
     8101 tccagttcca gatgcaagta aatggagtgt tcctcctttt gaagcgagaa tagtagatgg
     8161 gaaaatatat ggtagaggaa cttctgatat gaaggggcaa gtaagtgcta tgatggctgc
     8221 tgtttcatac tttgcagaag atactaataa agactttgaa ggtgaattgt acgtagcagg
     8281 tgttgttcat gaagaaatat ttgaaggagt ttcagctaga gagataagta aagctgttca
     8341 acctgattat gttgtaatag gtgaatcttc agaattaaac ttaaagatag gtcaaagagg
     8401 tagaggagaa atagtagtag aaacttttgg taaaccagct cactctgcta atccagaaaa
     8461 aggtataaat gcagtttata aaatggctaa tgtaatccaa aagatacaac aattagtacc
     8521 tccaactcat ccagttttag gtgatggaat attagtttta acagatataa aatcttctcc
     8581 atatccagga gcatcagtag tgccagatta ttgcaaagct acttttgaca gaagattatt
     8641 agttggagaa acaagagaag gagtattagc tccaatacaa gctttattag atgaaatgat
     8701 gaaagaagac ccagaattaa atgcaaaagt ttcttatgca gttgaaaaag ctgattgtta
     8761 cacaggaaat actatagaaa gtgaaagatt cttcccaggt tggttatatg acgaagaaga
     8821 tgaatttgtt caagcagcgt ataagggact aaaagaagct ggaatagatt cagaaataac
     8881 tcaatattca ttctgtacaa atggaagtca ctatgcaggt gaggctggaa taagaactat
     8941 aggatttgga ccttctaagg aaaatcttgc tcatacaata gatgagtata tagaattaga
     9001 ccaattattc aaaggtgcag aaggatatta tggtatatta aaatcagttt ataaaaaata
     9061 attaggagat ggttttgtga gaactttaat aaaacatggg cttatagtag atggaaataa
     9121 aacaccagca tatgaagggg atattttaat agaaaacgag aaaatattaa aaatatcaca
     9181 ggatttaaac gaagaagctg ataaagttat agatgcaaag ggtagagtta tatgtccagg
     9241 tttcatagat actcatagcc attcagacct agttatttta gttaatccat ataatgaggt
     9301 aaagattaga cagggaatta caacagaagt gttgggccaa gatggtatat ctatggcccc
     9361 tctacctcaa gagcatatat cttcttggag aaaaaattta gcaggtctag atggtgaaag
     9421 tgatgaaatt gattggaaat atgaaacaac agagaattat ttaaaaatga tggatgataa
     9481 cggggtaggt ttaaatgaaa cttatttagt acctcatgga aacgttagaa tggaagcaat
     9541 gggacttgaa gatagacctg ctactaaaga agaaattcaa aaaatgtgtg aaatcacaga
     9601 gagagaatta aaagcaggag ctataggatt gtctactgga cttatatata taccttgtgc
     9661 atactcattg actgaagaaa ttatagagat gtgtaaggta gtagcaaagt atgacggagt
     9721 atttgtagtt caccaaagaa gtgaagcaga tacaatttta acatcaatgg aagaaatcat
     9781 agaaattgga aaacaatcag gagtaaaagt tcatttttca cattttaagg tttgtggtaa
     9841 agcaaactgg aagtatatac cacaagttat agagctttta gaaaaagcag aaaaggaagg
     9901 cataagagta tcttttgacc aatatccata tgcagcagga agtacaatgc ttggagtagt
     9961 tttacctcct tgggcacatt ctggaggaac tgataagtta atagaaagat taagtgacga
    10021 aaatgaaaga gcaaaaatga aaaaagatat agcaaatgga atagaaggtt gggataattt
    10081 tatagaattt gctggaatag accaaatatt tgtaacaagc gtaaagacag aaaagaataa
    10141 ggatgtaatt ggtaagagtc tattagaaat tggaaaaatg agaggaaaag acccattaga
    10201 tgcaacgttt gatttattaa aagaagaaga aaatgcagtt ggaatggtag atttctatgg
    10261 attagaagaa catataatag gatttatgaa aagagacgag caaaatgtgt gtacagatgg
    10321 tcttttagca ggtaaaccac atccaagagc ttatggttct ttccctaaaa tactaggaag
    10381 atatgttaga gaattgaatg tactaacaat cgaagaagct gtttataaaa tgactaaaaa
    10441 agcagctaca agctttagta taagagatag aggcgaatta aaagaaggat attttgcaga
    10501 tatagttata tttgacaagg atacagttag tggttgtgat gattttatca actctatgca
    10561 gtaccctaca ggtatagatt atgtaattat aaatggaaat tgtgttgttg aagaaggaaa
    10621 atacaataaa attaaagcag gaaaagtact taaaaattaa atcttagctt taaggaggaa
    10681 taaatttatg attttagtgg ggaatgggag gctaataagc caagattctt taaatcccta
    10741 tatggaagat ggatgtgtag taataaatga taatctaatt gaagatatag gtactacaaa
    10801 tgaaatgaaa gctaaatatc cagtacatga atttatagat gcaggtaaga aaataattat
    10861 gcctggtcta ataaattcac atatgcatat atatagctca tttgctagag gaatggcagt
    10921 tccaggaaaa ccttctgaga attttttaga gatattaaac aatttatggt ggagacttga
    10981 taaacagctt acattagaag atacaaaata cagtgcatat gcaacgtata tagaatgtat
    11041 aaaaaacggt gtaacaacag tttatgacca tcatgcaagt ccaaatgcaa ttgaaggcag
    11101 tttgtttaca atatcagatg ttgcaaagga tttgggaatt agaacatgtc tttgttatga
    11161 agtatctgat agagatggtg gaaatacaat ccaacaaggt atcaatgaaa acgtaaactt
    11221 tataaaatac gctcaaaaag atgatacaga catgataaaa ggaatgtttg ggcttcatgc
    11281 tgcatttaca ctatctgatg atacattaaa taagtgtgct tcagagatgg ctggtcttga
    11341 tacaggttac catgtacatg ttgctgaagg actagcagac ttacaatata atgtagataa
    11401 atatggaaaa agagttttag aaagattcaa tgattttgga gtactaaaag aaaaaacaat
    11461 agcagttcat tgtatatata taagttcaga agaaatcagt cttttaaata aaacaaatac
    11521 atttgtagtt cataatccag aatctaatat gggaaatgca gttggatgtt ctcctgcaat
    11581 agagttatta aaaaggggtg ttacagtagg tctaggaact gatggatata ctagcgatat
    11641 gtttgaatca ttaaaagttg caaatataat ccacaaacat catttaaaag acccaagagt
    11701 tggatttgaa gaatcacaaa caatgttatt tgataacaat agaaaaatag caaaagctta
    11761 ttataaaaat gacctaggag tacttaaaaa aggtgcttat gcagatgtta tagtagttga
    11821 ttatatacca catactccat tgacagaaaa cacaatagga ggacacacta tttttggaat
    11881 gagtggaaga agtgtagata caactattat aaatggaaaa gtacttatga aagatagaaa
    11941 gttaataaac atagatgaag aaagtattct agcaaaaagt agagaattaa gtcaaaatct
    12001 atggaataga atttaaataa ttgatattaa tatacaagta agaaacaaga atttagatgt
    12061 taaaagcaga gcttaaacaa aaataggaat ttaaatgaag tatatgaata aaaaatatac
    12121 ggaatagaat attaaattaa atatagaagg gagacccaaa atgtctcaag ataaaagccc
    12181 taaaatagct ccagtagatg aaaggttacc tgtatccaaa tcttgggtat tttcactaca
    12241 gcacgtttta gcaatgtgtg caggagcagt agcagttcct atgatgatag gaagtgctgc
    12301 acgactagat catgctagta ttgttttttt aataaatgct tgcttgttta tggcaggtat
    12361 aggaacactc atacaaagtg ttggtatagg aaatattgta ggtgctaaaa taccagtaat
    12421 agaaggaact agttttgccg ctgtggcagg tatgacagca atagcctcat catatagtga
    12481 ttcacaagtt gcaatacaga cagtatttgg ctcagtaata gtagctggat tgttttgtat
    12541 actacttgct ccagtatttg aaaaactaat aagatttttc cctagtgtag ttactggaac
    12601 agttgttatg gtaataggta tttcactatt tccagttggg ataaaatgga taactgacaa
    12661 caaattggaa gcggttgaac caaactcatt agcattagct ttagcagtat tggcaataac
    12721 tttactttca tttaaattct taaaaggaat ttggaatagc acagctatat tggtaggtat
    12781 agtacttggt acactacttt ccatggcagt tggaatggca gattttagtg cagtaaatgg
    12841 agttggttgg cttaacttaa atgtaccttt aagatttgga atgcctagat ttgaaccatc
    12901 tgcaatacta tcattgtgtt taattatgtt ggtacttatg acggaatcag ttggtaatat
    12961 gatagctatt catgaaatgg tagacaaaga agtaacaggc aaaaatatta aaagaggtct
    13021 atttggagat ggaatatcta cagcattatc tggaatattc aattcatttc caataactcc
    13081 attcggtcaa aatacaggaa tagtaggtct tacaggtata aaatcaagat ttatagcagt
    13141 ttacgcaggg gttatattgc tagtacttgg attcttacca aaatttgcag caataatagg
    13201 agcaatacct aagcctgttc ttggaggcgt aggatttgca atgtttggaa tggtaatggt
    13261 tggaggagta aaaactttaa gcaaagtaaa atttgatgga actaaaaacg gggttatagt
    13321 agcagttagt gttggtttgt ctatgatacc actaacaaat cctgatttct atcataattt
    13381 cccaacttgg gtacaaacaa tattccacag tggaataaca acaggtagtt tatcagcagt
    13441 gattttaaac atattcttca atgaactagg ttctaaaaaa gaaaaaaata acaaagttga
    13501 agaagcaaag taaaaataag acaagtaaaa atctatattt attaaaagtc attaagcatt
    13561 gataaaagta attcagagat attaataatt caacaaaact atcttatatt ttaaataata
    13621 aaaaagtaaa taaataacga atacaaataa aaaaatacaa tctaaatatt aaaaatattt
    13681 aatttaaggg agagataatg atatggctaa tttaaaagtt aatttatatg gaatggaatt
    13741 tttaaaccca attatgacag cagcaggtcc tggagcaaaa gatggtgctc tctgtcaaga
    13801 ggcagcaaaa ggtggagcag gagctatatg tacaaaaact atatctgtat taccagctga
    13861 tgtaccaaga ccatgtatgg caaaaactaa tagtggtttc ttaaacacag aattatggtc
    13921 agagcttcca aaagagcaat ggatagaaga agaatacaaa aaggtaaaaa aaacagggct
    13981 tccagtaata gtaagtatgg gatattcagc agagcaaata gctgaggttg ctcctttagt
    14041 aaaaccttat gcagatgcgg ttgaattatc tactcattat gtaggtacag atgttgcgcc
    14101 aatagtaaat gctttaaaag ctgcaaaagc tgttttagat gtaccagtat ttatgaaaat
    14161 gagtcctcat actgacattc aaactattgc aaaagctgtt gaagaagcag gtgcagatgg
    14221 gcttgtaatg ataaactcat ttggaccatg tatggcaata gatgtaaata caggataccc
    14281 tataatggga agtaaagctg gatatggatg gttatcaggt gcaccaataa gacctctagc
    14341 aataagatgt atatacgaag cttctcaagt tgtaaatata ccaataatcg gtgttggtgg
    14401 aatcacttgt ggaaaagacg tagctgaaat gatgatggct ggagcaagtg ctgttcaagt
    14461 atgtacagaa gcaatcctta aaggaccttc tatctatgga aaaattgcta aagaattaaa
    14521 tgaattttta gatgaaaatg gatatgctga tgttaatgaa ataaaaggat taactcataa
    14581 gaaaatgaca gctagaggat ttagaactca ttcagtagct ccagtagtgg atgataacaa
    14641 gtgtatcaaa tgtaagcaat gtgtaacaag ctgtgtatat gaagctttag aagttacaga
    14701 taagttgaac atagatgcag acaagtgttt tggatgtgga ttatgtgtaa ctagatgtcc
    14761 aaaaggagct ttaagcatct gctacaatca agtagaagct atgaatgagt aataattata
    14821 tagaattttg gtaattaact tagagtaata ggtattagga taataaaata tatcagataa
    14881 acacgcatta tgcattaata atacagtcta aagttaataa ttttatgata ttgatttaac
    14941 taaatattag tttagctgaa tattaattta attaggtatt ggtttaatct taatatagat
    15001 ttactacgta taagtgaact aactagatta ctttaagtta attttttcat ataaaataaa
    15061 ttgatacgtt ataagtaagg tggagtctat atgggaattg ttttaaaagg tgggaaagta
    15121 gtaacaagtg aaaaaactta ctgtgcagat gtaagaatag aagatgaaaa aatagtcgat
    15181 ataggtcttg atatatcaaa agaaaatgat gaaatagttg atgttagtga ttcttatgtt
    15241 ataccaggag gtatagatac acacactcac tttgacttag atacaggtgc tactaagaca
    15301 gcagataact ttgagacagg aacaaaagct gctatagtcg gaggaactac tactatattg
    15361 gattttgcta cacaggctaa gggatgttct ttgaaagaag ggttagaaga atggcatgaa
    15421 aaagctaagg ataaatgcta ttcagattat gggtttcata tggctataac agactggaat
    15481 gactcggttt gtaatgaaat ggaagatatg gtgaaagagg gagtatcttc atttaaattg
    15541 tatatggcat ataaaggaag tcttcaagtt gatgatggtg tcatatttga agccttaaga
    15601 aaagcagaag agataggtgg aattattggt tttcattgtg aaaatgggga tataatatgt
    15661 gaacttgtgg ataaagcaaa ggcagaaaat aatttatctc caaaatatca tcaattaact
    15721 agaccagcta tactggaagc agaagctaca tcaagactta tgaagatagc tgaagttgca
    15781 aactctaaag tatacgtagt tcacttaagt tgtagagaat ccttagagga ggttctaaaa
    15841 gctaagcaaa gaggtgtgga tgtaatagtt gaaacttgtc ctcaatacct tctattaaat
    15901 gatggattat atgatttaga tggatttgaa agtgctaagt atgtaatgtc accaccttta
    15961 agagataaag aaaataatga aatattatgg aatgctattt cagataatca aatagatact
    16021 ataggaacag accattgttc ttttaattat aggggacaaa aggaacttgg aataaacgat
    16081 ttcagtaaga taccaaacgg ttctccaggt gtagaacaca ggatgagtct tttatacaca
    16141 tatggagtct gtaaaaataa aatatctatc aacaagatgg tagaagtaac atcaactaat
    16201 gcagcaaagt tgtttggaat gtatcctaat aaaggagcca tagaaatagg cagtgatgca
    16261 gatatattag tcttaaatcc aaacaaaaaa tctaaaatag aagcaaaaaa acaattacaa
    16321 aatgtagatt atacacctta tgaagggtat gaagtggatt gtcaaataga acatgtttat
    16381 ttaagaggaa aagaagtagt tagagatgga gaattaatct gtaatactcc aagtgggaga
    16441 tatataaata ggcgtctaac aaagggggct agagaatggt agaatttata ttaaatggag
    16501 agaaagttgt tgcaaaagaa ggcaaaaaac ttttagactt ccttagagaa gatatgaata
    16561 taacttcagt taaaaatgga tgttcagaag gtgcttgtgg aacatgtatg gttataattg
    16621 atggtaaagc gactaaagca tgtgtattta aaactgataa attagctggg aaaaacataa
    16681 caactataga gggattatca gagagagaaa gagatgtttt tgcatattct tttgctagtc
    16741 aaggagctgt acaatgtgga ttttgtattc caggtatggt aattagttca aaagcactta
    16801 tagacgttaa taataatcct actgaagatg atataaagaa agctttaaaa ggtaacatat
    16861 gtagatgtac agggtatgta aaaataatta aggctgtcga tttagcagca aagattttta
    16921 gagaaaatat agatgtgcca aaagtaaact gtaaaggtct agtaggtgaa aatcttccta
    16981 gagttgatgc agtcggtaaa gcacttggat attctgaata tgtagatgat atgagaattg
    17041 agggtatgat ttatggttca gcagttagag ctaagtatcc tagagcttta gttaaaaaaa
    17101 tagatataga agaagcaaaa gcttatccag gtgttgttgc agttctaaca gctaaagata
    17161 ttccaggaac tataaaggta ggtcacttaa aaaaagattg ggacacttta ataccagaag
    17221 gtgaaataac tagatactta ggagatggaa tagttttagt agcagcagaa actagagaag
    17281 cgttagaaga ggccaaaaag ctagttaaga tagattatga ggaattaaca ccattaagta
    17341 ctacagcaga tgctcttaga gaagatgctc caaagataca tgagacaggt aatatacttg
    17401 ttagggaaca tttagtaaga ggaaacgctg aagaaaagat agaaaattca aaatatgttg
    17461 taactaaaag atacactaca cctgctacag aacatgcatt tttagagcct gaatgtgcag
    17521 tagctggtcc ttatgaagat gatggagtaa taatctattc aacagaccaa ggggtgtttg
    17581 ccactcaaca tgaatgtgca gatatgttag ggttgccata tgagaaggta agagttataa
    17641 acaaaatggt aggcggagga tttggtggaa aagaagatat gagtgttcaa caccatgcag
    17701 ctttacttgc ataccatact aagagatttg taaaagtaca gttaacaaga aaagaaagta
    17761 ttattgttca tccaaaacga catgccacag aaatggaatt tacgacagca tgtgatgaaa
    17821 atggatactt aacaggtatg aaggcaacga taatatctga tacaggtgcg tatgcctctc
    17881 ttggaggacc agtgctacaa agattatgta ctcatgcagc aggaccatac aattatcaag
    17941 atattgatat aacaggaaca gcagtatata ctaataaccc tcctggagga gcatttagag
    18001 gatttggagt tacgcagagt tgttttgcaa cagaatgtaa tctaaactta cttgctgaaa
    18061 tggttggaat atcaccttgg gagataagat ataaaaatgc aataagacct gggcaagttt
    18121 taccaaatgg tcaatttgca gatgaaggaa cagcaatagc agagacacta gaagctgtaa
    18181 aagaagagta tgaaaagcat ccacgtgcag gtatagcttg tgccatgaaa aatagtggag
    18241 ttggagttgg tatacctgat gttggaagat gtagattggt tataaaagat ggcaaagttc
    18301 acataagaac aagtgcttct tgtataggtc aagggcttgg tactgttgtg actcaagtag
    18361 tttgtgaaac tgctaaccta cttcctgaaa atatagtgca tgaagttcca gatactcatt
    18421 taacaccaga ctctggtaat actacggctt caagacagac agtatttaca ggagaagcta
    18481 ctaaggttgc atcaagtaag ctaaaagaag ctttagactc tggtaaaact ttacttgatt
    18541 tagagggaga ggagttttat ggagaatatg aaagtattac agataaaatg ggttgtgaca
    18601 aagaaaatcc agtgagtcat gttgcttatg gatatgcaac acaagttgta atgctagatg
    18661 aaaatggaag attggaaaaa gtagtagcag cacatgacgt tggaagagct ataaatccaa
    18721 tcagtttaga ggggcaaata gaaggtggag tagttatggg tcttggatat gctctaaccg
    18781 aagattaccc agtagttaaa tctgtcccta cagctaagtt tggtacatta ggtttattta
    18841 aatctacaga tataccagaa atacaagctt taatagttga aaagaacaaa gatttattgg
    18901 cttatggggc aaaaggtgta ggagaaattt gtacagttcc tactgcacca gcagtacaaa
    18961 atgcctatta tgtatttgat aaagaattta gaactgaact accactacaa aatactccat
    19021 atagtaaaaa aaagtaacaa aaaaaagaaa tattaaataa aaaaatagat gaaattgtaa
    19081 ataaaaaaaa cccttttgca taaggtatat tttaaatgat agaatataca tatacaggag
    19141 ggtttttctt ttataaaata agtttaataa aattgagagg tgagcagaat gaattttaat
    19201 aatagtctag aattaactca gtctcagaag ctaataatga ccacacaact taagcaatca
    19261 ttatcaatat taaatatgag taagttagaa ttagaagaag agattaaaag agaagcagag
    19321 aataacccat tggttgaagt tgagaagagt ggggagataa attgggaaga atatataaaa
    19381 gatatggata ggtcaagacg tttagataga acagagataa gctataatcc tgataatgaa
    19441 gttaatctag aaaatttagt taaatattcg tcaaatttat atgaggattt aaaatttcag
    19501 ataagcctgt ataaacttac agataaagaa ttggaagtct gtgagtatat aattgatagt
    19561 ttagatgagg atggatattt aagaactgag gaaaaagtaa ttgttgatac cttaaagata
    19621 gatgaagaac tttttgaaaa atgcttgatt agtgttcagc agttggaacc tagtggagta
    19681 ggggcaagaa gtctttcaga atgtctgatg atacaaatgg ctagtttggg aatatataat
    19741 gaaattttag aggaaatcgt tacaaaagac ttaaatttaa ttgcaaataa taaatacaaa
    19801 gagataagta aaaagtacaa tatgtcatta cagaaatgcg ttgaactaat aaacataatt
    19861 aagacattag accccaaacc aggaagaact tgttcagtag agaaaagtgt atacattcaa
    19921 cctgatgtaa cagtagaaaa aattgatgat gaatttattg tatatttaaa tgaaaaagat
    19981 tcttatcaaa taagaatcaa tagttattat aaagacatat taaaaaattc acagtctgat
    20041 gaaagtgcaa aagaatttat aaaagaaaga ctaaattcag caacaggact tatgaaaaat
    20101 atagagagta ggaaaactac agtacttaag attgcagaag agatagtaaa agctcaagat
    20161 gaatttttga gaaaagggac aaaatatata aaacctttga aaatgaaaga catagcagaa
    20221 aaattagaat ttcatgaatc tactataagt agaggtgtaa atggtaaata tatgctaaca
    20281 ccttttggtg tatatgaatt taggtacttt ttcagtagtg ccattgagac tgagaataat
    20341 gaaatggcat ctagtacaag cataaaaaaa attataaagg aaacaataaa agacgaaaat
    20401 aaaaagaaac ctttaagtga tgaccatata tcgaagttac taaaagaaaa aggaataaat
    20461 gttgcaagaa gaacagttgc taaatatcgt gaagaattag gaatcccatc ttcgagtaaa
    20521 agaaaagaat actaataagt aaaagacaaa tatcagtata gtaaggggaa aaggctaatt
    20581 aaaagatgaa tgtggattag gctaaaaatt ttatgaaata aaataataaa atatggaaaa
    20641 gtattaaaat gctataagat attaaaaaac tggggaacat taaaacatta aagaacatta
    20701 gagctctaag gaatattaga attttaaaga agattaaaat ttagaaaata taaaaatact
    20761 aaaaagagct gaaaaactgg ggaacattaa aatattgtaa aatgctaaaa aattagaaaa
    20821 cataattaaa taagtgctta taaagaatga ttaaattaaa taagtgtttg taaagaataa
    20881 ttaaatatta gaaaaagaag aatacctaga taaataaact attattaaat ttaataatca
    20941 caaaaggaaa acacataggg tataaataaa aattttagct agacagaagt aaacttagct
    21001 ggaaataaaa gtaactagaa ataaaattat t
//
LOCUS       DAMKOJ010000061        20709 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000061 DAMKOJ010000000
VERSION     DAMKOJ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20709
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.066"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            366..677
                     /gene="rpsJ"
                     /locus_tag="PC592_002530"
     CDS             366..677
                     /gene="rpsJ"
                     /locus_tag="PC592_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDF4056483.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            769..1398
                     /gene="rplC"
                     /locus_tag="PC592_002531"
     CDS             769..1398
                     /gene="rplC"
                     /locus_tag="PC592_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDF4056484.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1428..2051
                     /gene="rplD"
                     /locus_tag="PC592_002532"
     CDS             1428..2051
                     /gene="rplD"
                     /locus_tag="PC592_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDF4056485.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNIIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2051..2341
                     /gene="rplW"
                     /locus_tag="PC592_002533"
     CDS             2051..2341
                     /gene="rplW"
                     /locus_tag="PC592_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDF4056486.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTASFKKAVVKLTADSKEIEFFQGM"
     gene            2371..3201
                     /gene="rplB"
                     /locus_tag="PC592_002534"
     CDS             2371..3201
                     /gene="rplB"
                     /locus_tag="PC592_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDF4056487.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3236..3517
                     /gene="rpsS"
                     /locus_tag="PC592_002535"
     CDS             3236..3517
                     /gene="rpsS"
                     /locus_tag="PC592_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDF4056488.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3549..3884
                     /gene="rplV"
                     /locus_tag="PC592_002536"
     CDS             3549..3884
                     /gene="rplV"
                     /locus_tag="PC592_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDF4056489.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3908..4723
                     /gene="rpsC"
                     /locus_tag="PC592_002537"
     CDS             3908..4723
                     /gene="rpsC"
                     /locus_tag="PC592_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDF4056490.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4759..5190
                     /gene="rplP"
                     /locus_tag="PC592_002538"
     CDS             4759..5190
                     /gene="rplP"
                     /locus_tag="PC592_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDF4056491.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5192..5395
                     /gene="rpmC"
                     /locus_tag="PC592_002539"
     CDS             5192..5395
                     /gene="rpmC"
                     /locus_tag="PC592_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDF4056492.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5419..5673
                     /gene="rpsQ"
                     /locus_tag="PC592_002540"
     CDS             5419..5673
                     /gene="rpsQ"
                     /locus_tag="PC592_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDF4056493.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5699..6067
                     /gene="rplN"
                     /locus_tag="PC592_002541"
     CDS             5699..6067
                     /gene="rplN"
                     /locus_tag="PC592_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDF4056494.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6091..6396
                     /gene="rplX"
                     /locus_tag="PC592_002542"
     CDS             6091..6396
                     /gene="rplX"
                     /locus_tag="PC592_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDF4056495.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6426..6968
                     /gene="rplE"
                     /locus_tag="PC592_002543"
     CDS             6426..6968
                     /gene="rplE"
                     /locus_tag="PC592_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDF4056496.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEIISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6986..7171
                     /locus_tag="PC592_002544"
     CDS             6986..7171
                     /locus_tag="PC592_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDF4056497.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7204..7602
                     /gene="rpsH"
                     /locus_tag="PC592_002545"
     CDS             7204..7602
                     /gene="rpsH"
                     /locus_tag="PC592_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDF4056498.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7633..8175
                     /gene="rplF"
                     /locus_tag="PC592_002546"
     CDS             7633..8175
                     /gene="rplF"
                     /locus_tag="PC592_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDF4056499.1"
                     /translation="MSRIGVKPIIVPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8211..8579
                     /gene="rplR"
                     /locus_tag="PC592_002547"
     CDS             8211..8579
                     /gene="rplR"
                     /locus_tag="PC592_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDF4056500.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8600..9109
                     /gene="rpsE"
                     /locus_tag="PC592_002548"
     CDS             8600..9109
                     /gene="rpsE"
                     /locus_tag="PC592_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDF4056501.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9124..9309
                     /gene="rpmD"
                     /locus_tag="PC592_002549"
     CDS             9124..9309
                     /gene="rpmD"
                     /locus_tag="PC592_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDF4056502.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9342..9785
                     /gene="rplO"
                     /locus_tag="PC592_002550"
     CDS             9342..9785
                     /gene="rplO"
                     /locus_tag="PC592_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDF4056503.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9829..11097
                     /gene="secY"
                     /locus_tag="PC592_002551"
     CDS             9829..11097
                     /gene="secY"
                     /locus_tag="PC592_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDF4056504.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGQVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11114..11764
                     /locus_tag="PC592_002552"
     CDS             11114..11764
                     /locus_tag="PC592_002552"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDF4056505.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVNYYSKQGIIADIKGDQAIDKVFEDIVTALGSGK"
     gene            11765..12511
                     /gene="map"
                     /locus_tag="PC592_002553"
     CDS             11765..12511
                     /gene="map"
                     /locus_tag="PC592_002553"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDF4056506.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12533..12802
                     /locus_tag="PC592_002554"
     CDS             12533..12802
                     /locus_tag="PC592_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HDF4056507.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12840..13058
                     /gene="infA"
                     /locus_tag="PC592_002555"
     CDS             12840..13058
                     /gene="infA"
                     /locus_tag="PC592_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDF4056508.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13094..13207
                     /gene="rpmJ"
                     /locus_tag="PC592_002556"
     CDS             13094..13207
                     /gene="rpmJ"
                     /locus_tag="PC592_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDF4056509.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13360..13731
                     /gene="rpsM"
                     /locus_tag="PC592_002557"
     CDS             13360..13731
                     /gene="rpsM"
                     /locus_tag="PC592_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDF4056510.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13767..14165
                     /gene="rpsK"
                     /locus_tag="PC592_002558"
     CDS             13767..14165
                     /gene="rpsK"
                     /locus_tag="PC592_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDF4056511.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14197..14820
                     /gene="rpsD"
                     /locus_tag="PC592_002559"
     CDS             14197..14820
                     /gene="rpsD"
                     /locus_tag="PC592_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDF4056512.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14898..15845
                     /locus_tag="PC592_002560"
     CDS             14898..15845
                     /locus_tag="PC592_002560"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDF4056513.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICSPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15866..16207
                     /gene="rplQ"
                     /locus_tag="PC592_002561"
     CDS             15866..16207
                     /gene="rplQ"
                     /locus_tag="PC592_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDF4056514.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16327..17160
                     /locus_tag="PC592_002562"
     CDS             16327..17160
                     /locus_tag="PC592_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF4056515.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDGMNTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISGDILTVDEMVMELCR
                     L"
     gene            17148..18014
                     /locus_tag="PC592_002563"
     CDS             17148..18014
                     /locus_tag="PC592_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF4056516.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDISFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEEFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKSLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFIGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18008..18811
                     /locus_tag="PC592_002564"
     CDS             18008..18811
                     /locus_tag="PC592_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDF4056517.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMISIFVVNKFWP
                     YIVVLLCLLAMIKLANIPIKYIVKGVKPLKWIILFTFFINIFFLPGDEIWSFGFLTIT
                     SQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18844..19575
                     /gene="truA"
                     /locus_tag="PC592_002565"
     CDS             18844..19575
                     /gene="truA"
                     /locus_tag="PC592_002565"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF4056518.1"
                     /translation="MRNIKITIQYNGKNYCGWQKQLDSLGIQGTIERAIYDITKEKVS
                     LIGSGRTDSGVHAIGQIANFKTNSSISIESIPMALNAKLPKDISVIDACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKLLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDIIRKDDLITFEISGNGFLYNMVRIIVGTLVDIGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19695..20126
                     /gene="rplM"
                     /locus_tag="PC592_002566"
     CDS             19695..20126
                     /gene="rplM"
                     /locus_tag="PC592_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDF4056519.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20155..20547
                     /gene="rpsI"
                     /locus_tag="PC592_002567"
     CDS             20155..20547
                     /gene="rpsI"
                     /locus_tag="PC592_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDF4056520.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8263 a         2458 c         4315 g         5673 t
ORIGIN      
        1 ctttactagc taatggattc aatataaaaa agagggggta acacctctct tttttgtttt
       61 ttattgacaa gtagctctaa agcatatata ctaaactagt gccttgagat agattaacaa
      121 tcaatttaag gttatgatgt tgtaatagaa aataaaattg aaaaaaagat aaaaaaaact
      181 tgaaaaaatg taacagatga tataaaatat aatagtgtgc ttgagagatt aagaaaataa
      241 gaattaaatc ctagtgaaat acgaactgat atcgatttga aagttacaac acacccggag
      301 cagtgtatcg gtattggttg tacgcagctt gaaaattaaa cacgtgataa aggagggaaa
      361 acaaaatggc taagaatgaa aaaataagaa taagattaaa atcatatgat cacaaattat
      421 tagatttttc agcaggtaaa atagttgaaa ctgctaaaaa ggctggatca caagtttcag
      481 gacctgtgcc tctaccaaca gaaaaacaag ttgtaactat attaagagct gtacataagt
      541 acaaagactc tagagaacaa tttgaaataa gaactcataa aagactaatc gacatagcta
      601 atccaacacc taagacagtt gactcattaa tgagattaga cttaccagca ggtgtagata
      661 tagaaataaa attataagaa cccctaagat attatcctat agatgattat cttagaatga
      721 ttactctaaa agatgtaatc cgctgtaaga attataggag gtgctaatat gaaaggaata
      781 ttaggcaaaa aagttggtat gactcaaata ttcactgata aaggtgtagt tatacctgta
      841 acagctgttg aagcaggacc tatggtcgtt actcaaataa aaacagttga taaagatgga
      901 tacaatgcta tacaaatagg ttttgaagat gctaaagaaa aagctttaaa caaacctaaa
      961 aaaggacatt tagctgctgc taatgtttta aagaaacatt taaaagaatt tagagtagat
     1021 tctgtagaag gatacacagt aggacaagaa ataaaagctg atgtatttga agcaggtgca
     1081 aaaatagatg ttactggaat aagtaaaggt aagggattcc aaggtccaat aaaaagacat
     1141 ggacaaagta gaggtcctga aactcacggt tctagatacc acagaagacc aggttcaatg
     1201 ggagcttgtt cttacccagg tagagtattt aaaaacaaaa aattagctgg acacatggga
     1261 agcgtaaagg taacagttca aaacttagag gttgttaagg tagatgctga taagaacctt
     1321 atattagtta aaggagctat accaggagct aaaggttcag tagtaactat aaaagaagct
     1381 ataaaggttt ctaaataatg actaacctag agaaaggagg aataacaatg ccaaaattaa
     1441 atgtactaaa tgttagtgga caaaacgttg gagaaataga attatcagat tctatatttg
     1501 gcgtagaagt taatggacat gttttatatg aagttgtaaa aaatcaatta gcaaataaga
     1561 gacaaggaac tcaatctgct aaaactagag cagaagttag aggtggcgga agaaaacctt
     1621 ggaaacaaaa aggaacaggt agagcaagac aaggttctac aagatctgta caatgggtag
     1681 gtggaggagt tgcttttgca cctaaaccaa gaagttacaa atatacatta cctaagaaag
     1741 taagaagatt agctatgaag agtgctttat cttcaaaagt tcaaaatagt gaagttatag
     1801 tattagatgc attaaacatg gatgctccta agactaaaga atttgctcaa atattaaaca
     1861 atataaatgc tgctaaaaaa gctttagtag ttatagctga caaaaacgat aacataataa
     1921 aatcagctag aaatatagaa ggtgttcaaa ctgcattagt taatactatg aatgtatatg
     1981 atatattaaa atatgattca tttataataa ctacagatgc tgttaaaaaa gtggaggagg
     2041 tgtacgcata atgactaatc cacatgatgt aataataaga ccagttgtaa ctgagcacag
     2101 tatggctgaa atgggtgaaa aaaaatacac ttttgttgtg gctaaagatg cgaacaaaac
     2161 tgaaataaaa aaagcagtag aaaaagtatt cggagttagt gttgataaag taaatacttt
     2221 aaactacgat ggaaaagtta aaagaatggg tagaactcaa ggaagaacag caagctttaa
     2281 gaaagcagta gttaaattaa ctgctgatag taaagaaata gaattcttcc aaggaatgta
     2341 gtattataac aaacgaagga gggaaaacag atggctataa aaaagtttag accaacttct
     2401 cctgccttaa gacaaatgac agttttagtt tctgatgaaa taacatgcaa tcaaccagag
     2461 aaatctcttt tagttaactt aaagaaaaat gctggtagaa acgtacatgg tagaataact
     2521 gttcgtcata gaggtggagg acaaaaaaga aaatatagaa taatagattt taaaagagat
     2581 aaagatggta tacctgctaa ggttgctact atagaatatg atccaaacag aactgcaaat
     2641 atcgcattat taaactatgc tgatggagaa aaaagatata tattagctcc agttggaatt
     2701 aacgttggag atactatatt atcaggatta ggtgctgata taaaaccagg aaactgttta
     2761 gcattaaaag atatgccagt tggtactatc attcataata tagaattaaa gccaggaaaa
     2821 ggagctcaat tagttagatc tgctggagtt tctgcacaat taatggctaa agaaggaaaa
     2881 aatgctttat taagattacc atcaggtgag atgagattag taagcataaa ctgtaaagct
     2941 actataggtc aagttggaaa tatagagcat ggtaacgtag ttatcggtaa agcaggtaga
     3001 aaaagacata tgggaataag acctactgta agaggttctg taatgaaccc taatgaccat
     3061 ccacacggtg gaggggaagg tagatctcca ataggtagac catctcctgt tactccatgg
     3121 ggtaaaccag ctcttggata caaaactaga aagaaaaata aagcttcaaa taaactaata
     3181 gtatcaagaa gaactaagta gtaaatttat ttttgctcgg aaaggaggaa tataaatgtc
     3241 aagatcaact aaaaaagggc cttttgtcca tgcaagactt ttaaagaaga tagaagctat
     3301 gaatgctagt ggaaataaag aagttataaa aacttggtca agatcttcaa ctgtatttcc
     3361 acaaatggta gaaaatacta tagctgttca tgatggaaga aaacatgttc cagtatatat
     3421 aacagaagat atggttggac ataaattagg tgagttcgtt cctactagaa ctttcaaagg
     3481 acataaggat gacgaaaaat ctaataagag aaaataatta aattatgact aagaaaggag
     3541 gaataacaat ggaagcaaaa gctactgcta aatacgtacg tgtatcacca agaaaagcag
     3601 gccaaatatg tgaccttgtt agaggaaaga atgttgatga agcattagca atattaaagt
     3661 ttactccaag aggagcagct tcaataatag ctaaagttgt aaaatcagct aaagctaacg
     3721 cagaaaacaa tcacgaaatg gatactgaaa aattatatat agcatcaata gttgctaatc
     3781 aaggaccaac aatgaagaga tttatgccta gagctatggg tcgtgcaact acaataagaa
     3841 aaagaacttc tcatatagag gttgttgtta aagagaaaaa ataattaata gataggaggg
     3901 aaagttaatg ggtcaaaagg ttaatccaca cggcttaagg gtcggtgtta taaaagattg
     3961 ggactcaaga tggttcgcta ctgataaaaa agagttcgga aacttattat tagaagacca
     4021 taatatacgt aaattcttaa agaaaagatt atactcagct ggagttgcta agatagaaat
     4081 agaaagatca gctaacaaaa taaaaatgga cttacatgtt gctaagcctg gtgtagttat
     4141 aggaagagct ggtgcaggaa tcgaagcatt aaaagctgaa ttagaaaaaa tgacaaagaa
     4201 aactataata gttaatatag tagaagtaag aagtacagat aaaaatgctc aattagtagc
     4261 tgaaaatata gctttagcta tagagagaag ggttgctttc agaagagcaa tgaaacaagc
     4321 tatacaaaga gcaatgaaat ctggtgctaa agggataaaa gtttctgctt caggaagatt
     4381 aggtggagct gaaatggcta gaactgaagg ttatagtgaa ggaaatgtgc cactacaaac
     4441 tttaagagca gatatagatt atggtttcgc tgaagctgat acaacttatg gaaaaatcgg
     4501 tataaaagtt tggatatgta atggtgaagt tttaccaact agagacggtg taaatccaag
     4561 agaagaaagc agaaagagcg atagaagaga caacaagaga gataatagaa gaaacgatag
     4621 aagaggaaat gacagaagag gaaatgataa cagaggaaac tacagaggac aaagacctca
     4681 aggtggatca agacctcaaa gaactgaaaa caaaggaaat taataatagt taggttcaag
     4741 gaaggaggaa aaatactcat gttaatgcca aaaagagtaa agcgtcgtag agttcataga
     4801 ggaagcatgg ctgggcaagc tcataagggt aataaagtta cttatggtga gtttggatta
     4861 gtagcattag aagcttcttg gataacttct aatcaaatag aagctgccag aatcgcgatg
     4921 actagatata taaaaagagg gggaaaggtt tggataaaaa tattccctca taaaccagta
     4981 acaagaaaac cagcagagac tcgtatgggt gcagggaaag gttctccaga atattgggta
     5041 gctgtagtta aaccaggaag agttatgttt gaattagcag gtgtttctga agataaagca
     5101 agagaagcta tgagacttgc tgcacataaa ttaccaatca aatgtaaatt tgttaaaaaa
     5161 gaagatttag aagtaaaggg tggtgaatag gatgaaagct aaagaattaa gagatttaac
     5221 aagcgaagag ctaatgaaca aattaaacga cttcaaaagt gaattattta gcttaagatt
     5281 ccaattagct actggtcaat tagaaaatac agctagaata aagtttgtta agaaggatat
     5341 agcaaaagtt aaaactgttc ttgctgaaag aaagttatac gaaactagag cttaatttgg
     5401 aaaggaggct ttttaaacat ggaaagagga agaagaaaag ttagaatagg ccgtgttgtt
     5461 agtgataaga tggataaaac aatagtagta gctgttgaag aattcgtacg tcatccacta
     5521 tataataaac gtgttaagag aactaagaaa ttcaaggctc atgatgaaaa gaatatatgt
     5581 aacatcggag atagagttaa aataatggaa actagaccat tatctaaaga taagagattc
     5641 agactagttg aagttgttga gaaagttaag tagtttttga agaaggaggg attacgatat
     5701 gatacaacaa gaatcacgtc taagagttgc tgataactca ggagctaaag aacttttatg
     5761 tatacgtgtt ctaggcggaa gtaaaagaag atatggtaac ataggcgacg ttatagttgc
     5821 tactgttaaa agtgcaacac ctggtggagt tgtaaaaaaa ggtaaggttg ttaaagctgt
     5881 tatagtaaga agcaaacaag gcgtaagacg taatgacgga agctatatat cttttgatga
     5941 aaatgctgct gttataataa aggacgataa aactccagta ggaactcgta tattcgggcc
     6001 tgttgctaga gagttaagag acaatgaatt catgaaaata gtttctcttg ctccagaagt
     6061 actataatta aggaggtgca ataggacatg atgcgtgtta aaaaaggtga cactgttgta
     6121 gttatagcag gtaaagataa aggtaaaaaa ggttcagttt taaaggtata tcctaaaact
     6181 agcaaagtgt tagttgaagg tgtaaatgta ataactaaac atcaaaaacc aagtgctatg
     6241 aaccaacaag gtggaataat aaataaagaa gccccaatac acatatctaa tgtaatgcca
     6301 tttgatcctg aaacaggaaa aggcgttaga gtaagatatg aagtaaaaga tgggaacaaa
     6361 gtaagagtat cagcaaagag cggaaaagaa ttataataaa tattgcttga aaggagggac
     6421 cttaaatggc ttctagatta caagaaaaat acatgaaaga agttgctcct gctttaatgg
     6481 agaaatttgg atacaaaaac gtaatggaga tacctaagtt aaataaaata gttattaaca
     6541 tgggtatagg tgacgctaga gaaaatccaa aaggattaga aaaaggcgtt gaagaattag
     6601 aaataatatc aggacaaaag cctgttataa ctaaagctag aaaatctgtt gctaacttca
     6661 aattaagaga aggaatgcca ataggaacaa aagttacatt aagagctgat aaaatgttct
     6721 actttatgga caaattagtt tcagtttctt taccaagagt tagagacttt agaggagtta
     6781 accctaatgc ttttgatggt agaggaaatt atgctttagg agttaaagaa caattaatat
     6841 tccctgaaat agaatatgat aaaatagata aagtaagagg aatggatata atatttgtta
     6901 ctacagcaaa gactgacgaa gaagctcgtg aattattaaa attattagga atgccatttt
     6961 ctaagtaagc aaaggaggga ttcccgtggc tagaaaagcg atggttgtta aacaacaaag
     7021 aaagcaaaag tacgctacta gagaatacac tagatgtact atatgcggaa gaccgcattc
     7081 agttttgaaa aaatttggta tatgccgtat atgctttaga gaattagctt ataaaggtca
     7141 aatacctggt gttagaaaag caagctggta gaagcttgat tagaatggaa ggagggcaac
     7201 aaaatgacaa tgacagatcc aattgcagat atgcttactc gtataagaaa tgctaatgtt
     7261 gttaagcatg aaactgtaga tgttccagct tctaatatga agaaagaatt agctagaatc
     7321 ttattagaag aaggtttcat aagaggttat gatgttatag aagatggaaa acaaggtatc
     7381 ataagaatac aattaaagta cggacaagaa ggcgaaagag ttataacagg tcttaagaaa
     7441 atatctaagc ctggaatgag agtttacgct gctaaccatg agataccaaa agtattaaac
     7501 ggattaggaa tatcagttat atctacttca aaaggaatat taactgacaa gcaagctaga
     7561 aaagaaaatg ttggtggaga agtaatctgc tacgtttggt aatcaatatg aacaatgtaa
     7621 ggaggtgcga ccatgtcaag aataggtgtt aagccaataa tagtaccagc aggtgttgaa
     7681 gttactatag ctgaaggaaa tttagttaca gtaaaaggtc caaaaggaac tttaactaaa
     7741 caattaagtg ctgagttaaa cataaaaaaa gaagaaaata caataatggt tgaaagacca
     7801 actgataata aaaaacatag atctttacac ggactaacta gaactttatt agataatatg
     7861 gttgtaggtg taaatactgg tttcgaaaag aaattagaat taaaaggtgt tggatataga
     7921 gctcaaaaac aaggaaagaa attagttatg aacttaggtt tctctcatcc agttgagatg
     7981 gaagatccag aaggaataac tgttgaagct ccaaaccaaa cagagttaat agtaaaaggt
     8041 atagacaagc aattagtagg gaactatgct gctaagataa gagcttggag aaagccagag
     8101 ccatacaaag gtaaaggtat aaaatacgtt gatgaagtaa tcagacgtaa agaaggaaaa
     8161 actggtaaaa aataatacca aaacttaaac gctagaaagg agtgagctag gtgttaaaaa
     8221 aggctgataa aaatgctaat agacttcaaa gacataagag agttcgtaga aaaataagcg
     8281 gtacttctca aagaccaaga ttatgtgtat ttagaagtgc taacaatata tatgctcaaa
     8341 taatagatga cacaaaaaga gtaactctag ttgctgcatc ttctttagaa gcagaagtta
     8401 agagtgctgt caatcataca ggaaacaagg aagcagctaa aaaagttgga gaattagttg
     8461 ctaaaaaagc tgttgaaaaa ggaatcactg aagttgtatt tgacagaggt ggatacttat
     8521 atcatggaag aattcaagaa ttagctgaag gtgctagaga agctggtctt aagttctaat
     8581 acgaaggagg gaaaaataca tgctacgtcg taagccgata gatgcaggac aacttgactt
     8641 acaagaaaaa gttgttgaag taagacgtgt tactaaggtt gtaaaaggtg gtagaaactt
     8701 cagatttgca gcattagtag ttgttggaga tgaaaacgga cacgttggta taggtgctgg
     8761 gaaagcaatg gaagtaccag acgctataaa aaaagcagtt gaagatgcta agaaaaatct
     8821 aatagtagtg ccaatagttg ggactacaat tcctcacgaa gtacgcggac actttggtgc
     8881 tggaaatata ttaataatgc ctgctgtgga aggtacagga gtaatagctg ggggacctgc
     8941 tagagccgta cttgagctag ctggactaaa agacgttaga gctaaatctt tagggtctaa
     9001 caatccaaga aatatggtaa atgctacaat agaaggactt aattctctaa aaacagttga
     9061 agatatagct aaacttagag gtaaaaaagt tgaagaactt ctagggtaag gaggtagtgt
     9121 aaaatggcta aattacaaat aaagttagtt agaagtgtta taggaactac tcctaaccaa
     9181 aaaaagaatg ttgaagcgtt aggattaaga aaaagagaac aagttgttgt aaaagaagac
     9241 aatgctcaaa caagaggtat gataaataaa gtaagtcact tattagaagt aactgaaata
     9301 gctgaataat ttttataaag tagtgcaagg aggtgcaatc catgaagtta catgagttaa
     9361 aacctgctga aggtgcagta agagctaaga gaagattagg tagaggtact gcaactggac
     9421 aaggtaaaac tgcaggacgt ggacaaaaag gtcaatggtc tcgttctggt ggtggagtaa
     9481 gagtaggatt tgaaggtgga caaatgccac tagctagaag acttcctaag agaggtttca
     9541 ataacatatt taagaaagtt tacacagaag ttaatgttga agttttaaac agatttgaaa
     9601 atggaacaga aataactgca gaattattaa aatctactaa aactataagc aaaataggta
     9661 aagatggaat taaaatctta ggtgaaggta atttagagaa agctttaact gttaaagctg
     9721 ctaaatttac agcttcagct caagaaaaaa tagaaaaagc tggtggaaaa gcagagttag
     9781 tataataacc tgctaatctc ctagccagta caggcggggt gaattagcgt gctgtcaaaa
     9841 ttaaaacaag cttggaagat taaagcagta agaaaaaaag taatgtatac acttatgatg
     9901 atcgtgatat tcagaatagg tactactata ccagttccag gcatagacac tagtattata
     9961 caaaagatgg taggcggcaa tagtctactt tctctgtata atatgtttac tggtggagct
    10021 tttagtaatt tttcactatt tgctttaggt ataagtccat atatcactgc atcaatcata
    10081 atacaacttc taacagtagg ttttgaaagt ttagcagaac ttcaaaaatc tggtgaagaa
    10141 ggaaagaaaa aaatcaataa gtacactaaa tatacagcac tagctctagc agttgtacaa
    10201 gctttgggaa ttacattagg aattgtaaga agtgctttaa tatcaaatag tgtgtttttt
    10261 atcacaactg ttgtaataac attagtttca gcaagtatgt tagtaatgtg gattggggac
    10321 aaaattactg aaaaaggaat aggtaatggt agttcagtaa taatatttgc aggtataata
    10381 tcaagaatac ctacagacgt tattaaaatc tcgcaacaag ttaaatctgg ccaagttgca
    10441 ccttgggtta tagtaattct agccgtagtt atattactta cagtaacagg agttacattt
    10501 atacaagaag caactagaaa gatacctgta caatatgcta aaagagttgt tggaagaaaa
    10561 atgtatggcg gacagagttc tcatatacca atgaaagtta accagtcagg agttatgcct
    10621 ataatttttg ctagttcact tttagctttc cctcaaacaa tagctatgtt tatgggtcca
    10681 aatgctcagg cttttgttca aaaatactta agtatggcaa cagaacaagg attttggaca
    10741 tatagatcaa ttgagattct acttataatt ttcttctcat atttttatac gactgtatca
    10801 tttaatacag aagacatatc taaaaatatg aagaataatg gtggatttat accaggtata
    10861 agaccaggtg aacctactat ggattattta aatagaattt taactagatt aactttagct
    10921 ggagctactt tcttagcaat aattgctatg gtgccagctc ttacaacaca ttatatgaaa
    10981 gtaaatatga gtctagctgg gacttcattg ctaatcgttg ttggagttgc tttggagctt
    11041 aagagacagt tagagtcaaa cttagttatg agaagctatc aaggtttctt aaaataaaat
    11101 ggagatggat aatatgagaa taatattact tggacctcca ggtgctggta aaggtactca
    11161 ggcggcagga atagtagaaa aatacaatat acctcatata tcaacaggag atatattcag
    11221 aaagaatata aaagagggaa cagaacttgg aaaaaaagct aaagaataca tggaccaagg
    11281 tttattagta ccagatgagt taactgtagg tttagttact gatagaatat ctcaagaaga
    11341 ttgtaaaaat ggatttatgt tagatggatt tccaagaaat gtagcacaag gagaacattt
    11401 agatatcttc ttaaaaaatg ctggtatatc actagataaa gttgtcaata ttgaagttga
    11461 taagagtata ctagtgtcta gagcagttgg tagaagaata tgtaagtctt gtggagctac
    11521 ttaccatgtt gagtttaatc ctcctaaagt agaaggtgta tgtgatgtat gccaaggaga
    11581 attatatcaa agagctgatg ataatgaaga aactgtatct aagagaatac aagtttatct
    11641 agatgaaact aagcctctag taaactatta tagcaagcaa ggtataatag cagatataaa
    11701 aggtgatcaa gcaatagata aagtatttga agatattgtc acagccttag gaagtggaaa
    11761 ataaatgatt atcttgaaat caaaaaaaga aatagaactt ttaagagaag caggcaaaat
    11821 agttgctgac actcatgaag ttttaagaaa agctatttct ccgggaatat ctactttaga
    11881 attagataaa atagctgaag agaatataag aaaatacaat gcagaacctt cttttaaagg
    11941 atatggaggt tttccaggaa gtatatgtgc ttctatcaat agagaggtag tacatggtat
    12001 tccaggagaa actatattac aagaagggga cattgtaagt ttggatatag gagcctatta
    12061 taaaggatat catggtgatt ctgcgaaaac tcatggagta ggcatgatat ctgaagaaga
    12121 taggaaattg atagaagtaa ctagagaaag cttctatgaa ggaataaaat ttgctaaatt
    12181 aggatataga ctttcagata tctcacacgc agtacaaaca cacgttgaga aacatggttt
    12241 ctcggtagtt agagatttag tgggtcatgg agttggagca aatcttcatg aggacccaca
    12301 agtacctaac tatggactcc caggaaaagg accaagactt agagaaggaa tggttattgc
    12361 tatagagcca atggttaatg caggtcgtta tcatgtaaag actctatcag atgggtggac
    12421 gactgttaca atagatggaa aaaaatcagc tcattatgag catacgatag caattactga
    12481 acatgaacct ttgatattga caaagttgta atttaaaaag taggtgaaaa aagtgctatc
    12541 agataattta agtataggtc aagttgttaa agtttcatta ggacgagata aaggaaattt
    12601 attctttgta gtcaaaataa ttaataatga atatgtatta atagctgatg gaaaaaagag
    12661 aaaacttgac aaacctaagt taaagaaagt gaagcactta aaaaaatata attttattaa
    12721 tgatgaagtt agaaaaagag tagtatctgg acaagagatt acagattctt ttttaagagc
    12781 tgaacttact aagttaaatt agataattta acttattgaa atggagggct ggttagttaa
    12841 tggccaaaaa agatgttata gaattagaag gtacagtttc agaagcttta cctaatgcta
    12901 tgttcaaagt taaactagaa aatggacatg agatattatg ccacatttct ggaaagctaa
    12961 gaatgaactt cataagaatt cttgaaggtg ataaggtgaa tgttgaactt tctccgtatg
    13021 accttacaag aggaagaatt acttggcgta agaagtagac tatattaata tttagtctaa
    13081 ggagggatta ataatgaagg ttagaccatc agtaaaacca atatgtgaaa aatgtaaagt
    13141 aataaaaaga aaaggaaaag taatggttat ctgtgaaaat ccaaagcata agcaaaagca
    13201 aggataagaa attattacta gcattttgtt aaattttata gtataatact atattgtgat
    13261 gttaacaaaa gaacgttaaa atcgttgaac aatctggcgt aggattggca tatgatgtga
    13321 agttttaaac actaaaaact atgtgtagga ggtgcgatca tggcaagaat agctggggta
    13381 gatttaccta gagaaaaaag agcggagata ggcttaactt atatatatgg tataggtaaa
    13441 gcgactgcta acgaaatatt agctaaggct gagataaatc cagatactag aataaaagat
    13501 ttatcagaag atcaagttaa tgagttaaga aaagttatag atgacgattt cttagttgaa
    13561 ggtgacttaa gaagagaaat tgctttaaac ataaagagat taagagatat caaatgttat
    13621 agaggaataa gacacgctaa aggtcttcca ttaagaggac aaagaactaa gactaatgct
    13681 agaactagaa aaggtcctag aaaaacagta tctcgtaaaa agaaaaaata aataaataat
    13741 aactagatga aggagggaaa aggaaaatgg ctaaaccaaa aaagaaagtt acacgtatta
    13801 gaagaagaga acgtaaaaat atagaacgtg gtcatgctca tatacaatca actttcaata
    13861 atacaataat aactttaact gacgttcacg gaaatgctat atcttgggca agttctggac
    13921 aattaggatt caaaggatca agaaaatcaa ctccatttgc atctcaaatg gctgctgaaa
    13981 cagctgcaaa agctgcgatg gaacacggac taaaaagtgt tgaggtattc gtaaaggggc
    14041 caggttcagg aagagaagct gcaataagag ctttacaagc aactggacta gaagtaacta
    14101 tgataaaaga tgttactcca atcccacata acggatgcag accaccaaag agaagaagag
    14161 tgtaattaat aagagtacaa taggaggtgt agataaatgg caagatatac aggtgcatca
    14221 tgtagacaat gccgtagaga gggaatgaaa ttattcctta aaggtgatag atgttataca
    14281 gataaatgtg ctatagtaaa aagaaactat gctccaggtc aacatggcca aggaagaaag
    14341 aaagtttcta actatggatt acaattaaga gaaaaacaaa aagttaaaag aatatatgga
    14401 gttttagaga ctcaatttag aaatttatat gaacgtgctg aaaatatgcc tggtaaagca
    14461 ggtgagaact tattaagttt attagagaga agattagata atgtagttta cagaatggga
    14521 ctagcatctt ctagaaaaga agctagacaa ttagtgactc atggtcattt cactttaaat
    14581 ggaaataaag tagacatacc ttcattaata gttaaggttg gagatgttat agaagttaaa
    14641 gagaaatcaa gatcttctgc aaaattcaaa aatttagtag aagttaactc aagaatagct
    14701 cctaagtggt tagaagctaa tgtagaagga atgacagcaa aagtagttgg tgttccaaca
    14761 agagaagata tagatcttga gatagcagag cacttaatca tagaacttta ctctaaataa
    14821 taagcacact tttaaaaatt attttaaaat tttgtttacc ctcagtggat tactgaattt
    14881 taaggagggt tttgtccatg atagaaatag aaaagccaaa agtagatata gttgagctta
    14941 gcgaagacta tagatatggt aaatttgtta tagagcctct agaaagagga tatggaataa
    15001 ctataggtaa cgcattaaga agaatattat tatcatcact accaggtgta gcagtgaacg
    15061 ctataaaaat agatggagtt cttcatgaat tttcaacaat acctggtgtc aaagaagatg
    15121 ttactgagat aatattgact ttaaaagagc tttcagcaac tatagatggt gaaggaagta
    15181 gaacacttaa aatagaagct caaggaccat gctctatcac aggtgcagat ataatctgtt
    15241 ctccagatgt agaaatatta agtaaagatt tagcaatagc tacattagat gataatgcta
    15301 agcttaatat ggagatattt gtagataaag gtagaggtta tgtttctgct gaagaaaata
    15361 aaacagagaa tgttccaata ggtgttttac ctgtggattc aatatatact cctgttgaga
    15421 aggttagtta tcatgtggaa aacacaagag ttggtcaaaa aacagattat gataaattag
    15481 tactagaagt ttggactaat ggtagtataa atcctcaaga gggtatatca ctagctgcaa
    15541 aggtactagt tgagcattta aacttattta tagacttaac tgaacatgta agtagtgttg
    15601 aaatcatggt agaaaaagaa gaagatcaaa aagaaaaagt tcttgaaatg actatagaag
    15661 aattagattt atcagttaga tcatataact gtttaaagag agcgggaatt aatacagttg
    15721 aagaattagc taataaatct gaggatgata tgatgaaggt tagaaaccta ggtaagaagt
    15781 cattagaaga ggtaatacaa aaactagaag aacttggatt gggattaaaa ccaagtgaag
    15841 aatagcgagc aaaggaggga taagaatggc taagtaccgt aaattaggac gtgaaacagc
    15901 tcacagaaac cttatgttaa gaaacttagt aacttgttta ctaagaagtg gaagaataga
    15961 aactacagtg actagagcga aagaaactcg tagaatggct gaaaagatga taactcttgc
    16021 taagagagga gatcttcatg ctagaagaca agttttagct tatgttatgg atgaaacagt
    16081 agttaataac ttattcacag atttagctcc aaaatatgct gagagaaatg gtggatacac
    16141 tagaataata aaaatagggc caagaaaagg cgatgctgct gaaatggctt ttatagaatt
    16201 agtatagtaa ggaaaggatt aggcttgatg gcttaatctt ttttttattt ttttgactaa
    16261 ggtatgatat aataatgtgt aaaatgattt ttataagtta ttgcttacta aaaggagtat
    16321 gaattaatgg ataatatagt aaaggtaaat aatatttcgt ttgagtatat tacagatgaa
    16381 gcaaaactta aagcaataga taatttaagc ctagatgtta aaaagggaga atttgttgcg
    16441 ataataggac ataatggttc tggtaagtct actttatcta aaaacttaaa tgctattctt
    16501 atgcctactg aaggaaatat tcttattgat ggtatgaata ctaaagaaga agaaagatta
    16561 tgggatataa gacaaactgc aggcatggta tttcaaaatc cagacaatca aatagttgct
    16621 actatagtag aagaagatgt tgcatttgga cctgagaact taggtataga accaaaagaa
    16681 ataagacgaa ttgtagagga gtctttaaaa agtgtaggta tgtatgattt aagagataga
    16741 cagcctcact tgttatcagg aggtcaaaag caaagagttg caatagcagg aattattgct
    16801 atgaggccta aatgtataat atttgatgaa gcaacagcaa tgttagatcc atctggaaga
    16861 aaagaagtta tgaaaacaat aaaaagactt aataaggaag aaaatataac tgttatacat
    16921 ataacacact ttatggaaga agcagtagaa gctgatagag ttgtagttat ggaaaaaggt
    16981 aagaaaatct tagagggaac tcctagagaa gtatttagta aaataaagat gttaaaggaa
    17041 atcggtttag atgtcccttg tatgacagag ttatctagtt tattaataga agaaggtata
    17101 aatattagtg gtgatatatt aactgtggat gagatggtga tggaattatg tcgattatag
    17161 taaagaactt aacacatata tataatgaag ggatgccttt tgcaagtaag gcacttgatg
    17221 atatttcttt tgagattaaa gatagagatt ttgttggtct cataggtcat acaggctcag
    17281 gaaaatctac attaatacaa catttaaatg gattactaaa gccttcctca ggagaaatat
    17341 ttataaatga ttttaatata acagataaaa acttgaattt aactgagatt agaaaaagag
    17401 taggggtcgt atttcaatat ccagaatatc aattgtttga agaaacgatt gataaagata
    17461 tagcctttgg accctctaat ttgggcttag aggagtccga gatacataat agggtaaaag
    17521 catcgatgga agctgtagga cttgattatg aggaatttaa agataaatct ccttttgaat
    17581 tatctggagg acaaaagcgt agagtagcaa ttgctggagt tatagccatg aacccagaag
    17641 ttctcatatt ggatgaacca actgctggtc ttgaccctgg tggaagagat gaaattttta
    17701 acttaataaa aagcttacat gaaaaaaaga atatgactat aatactatca tcacatagta
    17761 tggatgatat ggcaaaatta gcaaaaactt taattgttat gaatcatggt agtgtagaat
    17821 ttataggaac tcctagagaa gtatttaaat caaacgctag taaattaaaa gatataggat
    17881 tagatattcc acaagtttta gagcttgcat tgaaattgag agaaaaaggc tttgacatca
    17941 gtgaggatat cttgacttta gaagaagcca aacaggaaat attaaaagtt gtgagaggac
    18001 gaggattatg ttaaaagata taactatagg gcaatactac ccaacaagtt ctgctattca
    18061 taaattagat ccaagaataa agcttgtagc aacaattgta tttatgatat ctatatttgt
    18121 agtaaataaa ttttggcctt atatagtagt tttattatgt ttattagcta tgataaaatt
    18181 ggctaatata ccaatcaaat atattgttaa gggtgttaaa cctcttaagt ggattatttt
    18241 gtttacattt tttataaata tttttttctt accaggtgat gaaatatggt catttggatt
    18301 tttaactatt acaagccagg gtctaagaca agcaattttt atggcaataa gattaatatt
    18361 tttagtagtt ggtacatcat tgcttacttt aacaacttca ccaatagaat taactgatgg
    18421 aatagagaga ttgttgaacc catttaagaa aattggtttg ccagttcatg aacttgcaat
    18481 gatgatgaca attgctttac gttttattcc tacgttatta gatgagacag ataaaataat
    18541 gaaagctcag atgtctagag gtgcagattt tgaaagtaag aatcttataa atagagcaaa
    18601 gaatttagta ccacttttgg tacctttatt tgtgagtgca tttagaaggg ctgatgaatt
    18661 ggctatggcc atggaggcca gatgttacag aggtggacat aatagaacta agatgagaga
    18721 gtctgttata tcaagaagag attatatggc atgtgtattt caggttgtct atctaggagc
    18781 aattatagct actagattta tagcaattta attaataagt tatagatata aatgaggtaa
    18841 aatatgagaa atataaaaat tacaatccaa tacaatggta agaattattg tggatggcaa
    18901 aaacaacttg attctttagg gatacagggt acaattgaaa gggctatata tgatataaca
    18961 aaagaaaaag taagtcttat agggtctggg agaactgatt caggggttca tgctattggt
    19021 cagattgcaa actttaaaac taattcaagt ataagtatag aaagtatacc aatggcacta
    19081 aatgccaagt taccaaaaga catatcagtt atagatgcat gtgaagtaaa tgatgatttt
    19141 cactcaagat atagtgcaaa aggtaaaaca tataaatatt tagtatataa tagcaagttt
    19201 agaaatccaa tacttagtga gatatcatat caagtaaaat atgaacttga ttttgataaa
    19261 atgtgttcag aagcaaaact tttattagga acacatgatt ttaaaggctt tatgagttct
    19321 ggctcgtctg taaaagatac agttagaacg atatatgata ttgatataat tagaaaagat
    19381 gacttgatta cttttgagat tagtggtaat ggttttttat ataacatggt gaggattatt
    19441 gttggaacac ttgttgatat aggtcgtggt agaattaacg aaccattttt agatataata
    19501 caatcaaaaa ctaggtcaag atgtggacat acagctccag cacaaggatt atttctcaaa
    19561 aaagttcatt attaacttga cacaccaggc tacatgtatt aaaatatatg agaatgtgtt
    19621 aataagtcca cttgccccgg acttgacata aacggtaaaa aaattttatg aaaagtagtt
    19681 aaggagggac agttatgaaa agttatatag ctaagccagc tgatgtacaa agaaaatggt
    19741 acttagttga tgctgaagga aaaacattag gtcgtttagc aacagaaatt gcgacagtat
    19801 tgagaggtaa acataaacca acatttactc ctcacgttga tggtggagat tttgttgttg
    19861 tagtaaatgc agaaaaaata gttttaagtg gtaagaaatt agatcaaaaa tactacagat
    19921 accatactgg ttatgtaggt ggattaaaag aaatatctta cagagatatg atggataaga
    19981 aaccagagga agttatatca catgctgtaa gcggtatgtt acctaaaaat aaattaagaa
    20041 gtagaatgat gactagatta agagtatttg caggtgctga gcacactcat gcagctcaaa
    20101 atccagaagt tttaaacttt aagtaagatt aataggtgaa aggaggagtt tataatggct
    20161 aacgttcaat attatggaac tggaagaaga aaaagttctg ttgctagagt aagactagtt
    20221 gcaggtgaag gaaatatatt agtaaatgga agagcattag aaaattattt taactatgag
    20281 acattaataa gagatgttaa acaaccatta gttttaactg gtaatgaaaa taaatatgat
    20341 gttatagtaa aagttgaagg tggaggattc actggacaag ctggagctat aagacatggt
    20401 atatctagag ctttattaaa agctgattta gatttaagac ctgctttaaa gaaagaaggt
    20461 ttcttaacta gagatgcaag aatgaaggaa agaaagaaat acggattaaa agcagcaaga
    20521 agagctccac aattctcaaa aagataatta cttatttttt tggaaaaaca aaatccttta
    20581 tttactgcta ttcagaaaat attggtattt taaaaatgtt gggttaagtt aattattaat
    20641 atataataaa ataataagat atcttattag gatgtttttc attaagaaaa gcatcctttt
    20701 tattttgac
//
LOCUS       DAMKOJ010000062        20458 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000062 DAMKOJ010000000
VERSION     DAMKOJ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.067"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            88..762
                     /locus_tag="PC592_002568"
     CDS             88..762
                     /locus_tag="PC592_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056521.1"
                     /translation="MFKIMVVEDDVSLKNIIAECLTKWGHNVHQIENLENIIEEFKNY
                     KPQLVLLDINLPFYDGFYWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSIDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIN"
     gene            786..1790
                     /locus_tag="PC592_002569"
     CDS             786..1790
                     /locus_tag="PC592_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4056522.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTIAVIIFSPVDVFLIDTILYI
                     LVINVVFLFLYLFISYIKKNKFLDKIKNDTFKININTTELAKCKNEEKIYLNIIKNHQ
                     YQCNNIINKNIKKFEENKEILNMWVHDVKIPIAIIKLTLEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILNLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRSKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIAVDSEYNQYTKFTITFKCDL
                     "
     gene            1901..3133
                     /locus_tag="PC592_002570"
     CDS             1901..3133
                     /locus_tag="PC592_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF4056523.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRSSSFGSSGFNSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTKLQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENRDAIASINAQITTLNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVSNSSFKIPASCVLKDKKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     NGDTTPNKKVEEVNMDVN"
     gene            3141..3815
                     /locus_tag="PC592_002571"
     CDS             3141..3815
                     /locus_tag="PC592_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056524.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKSLKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            3818..5050
                     /locus_tag="PC592_002572"
     CDS             3818..5050
                     /locus_tag="PC592_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056525.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLIPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVISKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIIATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(5335..6600)
                     /locus_tag="PC592_002573"
     CDS             complement(5335..6600)
                     /locus_tag="PC592_002573"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDF4056526.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMVKAKELDVPLSFHEEDPSLVGNPGVNAGKIASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSREEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSTNPAKLYNLNTGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKINYTICNGKIVYNA"
     gene            complement(6653..7801)
                     /locus_tag="PC592_002574"
     CDS             complement(6653..7801)
                     /locus_tag="PC592_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF4056527.1"
                     /translation="MKSVSVRSCKTYNYEEVRLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKVHSEKAHVLKYMDIIKPVVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLIPNRVATIRGAIKRGYIREDFSDIEILG
                     EDINDLIIKNYKVPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPAATIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(7892..8437)
                     /locus_tag="PC592_002575"
     CDS             complement(7892..8437)
                     /locus_tag="PC592_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF4056528.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(8660..9604)
                     /locus_tag="PC592_002576"
     CDS             complement(8660..9604)
                     /locus_tag="PC592_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF4056529.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVIVQAFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            9990..10871
                     /locus_tag="PC592_002577"
     CDS             9990..10871
                     /locus_tag="PC592_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF4056530.1"
                     /translation="MVKKRKKKTVALTIIVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAIKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPGRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(10932..12140)
                     /locus_tag="PC592_002578"
     CDS             complement(10932..12140)
                     /locus_tag="PC592_002578"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDF4056531.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKDGSVNPRDIKMNLAREIVTLYHGEESAREAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVVNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(12213..12465)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(12616..13605)
                     /locus_tag="PC592_002579"
     CDS             complement(12616..13605)
                     /locus_tag="PC592_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HDF4056532.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIISVSTGFGYAIYLDF
                     IVPIFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWATQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKLLIFKNFRTLNQFLCCSKKVFYICV
                     SYLTIFEVVKLLNVKVDFVYLKTVFISIAYLCVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RISFLIIILLLFFMFDVTVISLIIINAFLNKKINIRLSQNNIVNKQINLLIEK"
     gene            13757..14197
                     /locus_tag="PC592_002580"
     CDS             13757..14197
                     /locus_tag="PC592_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4056533.1"
                     /translation="MFKIKHFNDLNLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKN
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSRHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            14524..14751
                     /locus_tag="PC592_002581"
     CDS             14524..14751
                     /locus_tag="PC592_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF4056534.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            14777..16897
                     /gene="feoB"
                     /locus_tag="PC592_002582"
     CDS             14777..16897
                     /gene="feoB"
                     /locus_tag="PC592_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF4056535.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKHKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEAIKKGITIDKKLLEDSLC
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(17010..17828)
                     /locus_tag="PC592_002583"
     CDS             complement(17010..17828)
                     /locus_tag="PC592_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4056536.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKSEEYLVLSSDLSNMSNGDFMMELIDFTNYCK
                     AKNLYQGYELGVIVSNENLKNGDYLSISSFYLKIDKKIKDKRLYIKPEGMYACIKHIG
                     KYENSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            complement(18282..20375)
                     /locus_tag="PC592_002584"
     CDS             complement(18282..20375)
                     /locus_tag="PC592_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4056537.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIVFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVVELLKNDKKGVLIKWYEKCNKLNCVFENYDSLITWQD
                     GTVVHMHQSIDITNSTSLNKQIKPNEFHKISNTEEEKGVFNVSIDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLIYWEKIVHPEDWKRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGKPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGIIVDNVEEKEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKYASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTQSHKIIGVEVLLRWTNDKYKAISPLEFIPILEEHDMIN
                     TVGAWVLRMALRTFKGLIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDEKFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDVVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQMKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         7196 a         3128 c         2602 g         7532 t
ORIGIN      
        1 tattttagat aataaggtag aaatatttta gtttatcaag taaaatatag ttatgttaat
       61 ataactattt taaattggga ggtaagaatg tttaaaataa tggtagttga agatgatgtc
      121 tcattgaaaa atatcatagc agaatgtctt actaaatggg gacataatgt tcatcaaata
      181 gaaaatcttg aaaatataat agaagagttc aaaaactata aaccacagtt agttttattg
      241 gacataaacc ttccatttta tgatggtttt tattggtgta atgaaataag aaaaatttca
      301 aaagttccta taatctttat ttcttcaaga aattctaata tggatgtaat aatgggtgta
      361 aatctaggtg cagatgatta tatacaaaaa cctttttcta tagatgtctt agtggctaaa
      421 gttaatgccc ttttaagaag aacttataat tttgttgata ataactcaaa tcagattatt
      481 cacaatggtg ttactttaga tttatcaact gcaacaataa actatgaaga taataccatt
      541 gagctaacaa aaaatgaaat caaaattctc catgagctta tgaaatataa aggtcagata
      601 gtaagtagaa ataaactcat gaaaaagtta tgggataatg attggtttgt agatgataat
      661 acattaactg tcaacgtaaa tagaatacgc tcaaaattaa atgaaattgg tctagaagat
      721 tttatagaaa caaaaagagg attgggttat ataatcaatt aaaacgattc taagtaggtg
      781 aatttatgag ctttaaagat tttctcaaag ataagttagg ttttttagta tacaatttta
      841 ctttcttaat ttttacaata gcagttatta tattttctcc tgtagatgtt tttctgattg
      901 atactatttt atatatatta gttataaacg ttgtgttttt atttctctat ctatttatta
      961 gctacatcaa gaagaataaa tttttagata agataaaaaa tgatacattc aaaattaata
     1021 taaatactac agaattagct aaatgtaaaa atgaagaaaa aatatatttg aatattatta
     1081 aaaatcatca atatcaatgt aataacataa taaacaagaa tattaagaag tttgaagaaa
     1141 acaaagagat tttaaatatg tgggtacatg atgtaaaaat tcctatagct ataataaaac
     1201 tcaccctcga acaaaatgaa aatttaattg atgaaaaaat ttcagatgac atagatagtg
     1261 aaatatttag aattgaaaac tcagttgaaa aaattttata tttatcgaga cttgaagatt
     1321 ttcataagga ttttttaatt caagaggtaa atattgaaaa aataattaga aatattataa
     1381 aaaaatactc aaaatatttt atttcaaaaa aaattatttt aaacttaaat aatttgaatt
     1441 ttaaagtttt atctgacgaa aaatggctct acttcatatt cgagcaatta ttgagtaatt
     1501 ccctaaaata ctcctcatta ggagataata tatctatcta ttgcaaaaga agcaaaaatt
     1561 atttacaatt aagggtggaa gatactggct gtggtataaa aaaggaagat ttaaatcgaa
     1621 tattcaataa gggatttaca ggtaataatg gaagaaacaa ttctaaatct acaggacttg
     1681 ggctttattt agtaaaagaa ctttgtgata agcttggcca taaaattgct gtagattcag
     1741 agtacaacca atatacaaaa tttactatta cattcaaatg tgatttatag tatcttatta
     1801 ttgatagttt attttcatta acttatattc aacttcttat agtaattcta tatgtacatc
     1861 ccagtatata ataagtagtt tttataaaaa ggaggaagac atgtcttttc taaaaaaatt
     1921 taaaaataaa agatttagaa ataacagttt taaaagtaac aactttagaa gtagcagttt
     1981 tggaagtagt ggcttcaatt ctaagaataa gggttttaaa aacaatcctt ttaaaaataa
     2041 gagattcaaa atatatgcag gaatagctgt aatcatactt ctaattctag gagttcttgc
     2101 ttatgttgat tcaaaaaaca ctaaattaca agctaatgaa aactttatcg aaacatatac
     2161 tattcctgaa aatgaaaaaa tatttataaa tgggatggtc gttcctaagc aaactaagga
     2221 tttcaatata tctggagatt atgagttaag tgatgttaat gttacaaatg gtcaaaaagt
     2281 aaatcaagga gaccttcttt ttactgctaa aaatccaact ataatagcag aaatagatag
     2341 tttaaaatca caacttagtc aatacaaaaa acaaaaaata tcactttctg atattgctga
     2401 aaatagggat gctattgcct ctataaatgc acagataact actttaaact ctcagatagc
     2461 ttctctggat aaaaaagcgt atgacagagt tactgcacct tttgatggta cagtatactt
     2521 gaatgaccaa actggaaacc cagaccaacc agtctcattt atgactatcc aaggtctaga
     2581 gttttatatg aaaggacaag caagtgaaca agatttacct aaaatgaaga ttgaccaaat
     2641 ggtcaatata ttagtttttt caactgacca aaagcttact ggtagaataa gttttatatc
     2701 tgataaacca tctactccaa acactgaaat gggagctcag cagaatacac tgtcttatta
     2761 tgatataaac atagcatttg ataatcaaga aggattagta aatggattcc atcttcaagc
     2821 atcacttgaa gtatctaatt caagctttaa aataccagca tcttgtgtgc ttaaggacaa
     2881 aaaacactca tatgtattta aggatttaga tggtatattg aaaaagcaaa ttgtagatgt
     2941 agcaagtcaa aatgatgatt ttgctgtagt tagaggcggt cttgaacaag gcgatataat
     3001 aataaaacac cctactaaag aaatgaaaga aggagaccca gttcaaggtg atggcgtaac
     3061 tgctggttct aataataatg gagatactac tccaaacaaa aaagtagaag aagttaatat
     3121 ggatgtgaat taatttacat atgttaatta aattagaaaa tattcaaaaa tattacaaag
     3181 tagggaaaga tgaattacat gttttaaaat ccttaaattt agaaattgaa tctggagaat
     3241 ttgtcatgat aatgggtaaa tctggtagtg gtaaaactac tttacttaat atcttaggtt
     3301 ttctagatgt atttgatgaa ggaagatata tatttgatgg aacagatgta actaatttga
     3361 gtgaaaatga acgttctgtt tttagaaata ttaatattgg atttgttttc caacaattta
     3421 atttaataga aactctaaat gtatatcaaa atgtagagtt gcctctaatt tacaataaat
     3481 cgctaaaaaa atctaataga gaagaaattg ttaaagataa attaagttct gttggacttt
     3541 tggataagct taaacaaaaa ccgcttcaat tatctggtgg tcaacaacag cgtgtagcca
     3601 ttgcacgttg cttagcaaat gaccctcaaa ttatctttgc agatgaaccg actggggcat
     3661 tagatagtga aactagcaga gaaattatgg agcttttaac aaggctcaac aaacaaggta
     3721 agactataat aatggttaca catgatcaag atttaactaa gtatgcaact aaggttatac
     3781 gacttaaaga tggtgtgttt acttcggagg tgtaatcatg agtttattaa aaaattcttt
     3841 ggccaattta aaaggtcaca agcttcgtgt atttgtagct ttactctgga ttataatagg
     3901 aataacttca gtgatacttg ttagttctat aggtaatgga tttcaaaaag aaattaaaaa
     3961 atctgtaaac aatgtaaacc ctaataaaac tactatttca tttgagtcag ctgataacac
     4021 aggtcttact gatgatatga gtattttttt aaaaccattt aacgcgaaag acttagaaga
     4081 gttatcattt gttgaaggag tagaaagaat agctccttca agagatgggt ttaaccttga
     4141 ttcagtttac tcttcacaag catcttttga taaaaaaact acgtatgttg atgttggacc
     4201 agtaaaaaaa gattctaaaa taaatttaat ttgtggtaga gatttttctt tagatgatga
     4261 aaaaagaaaa gtaattttac ttacattaca aagtacaagt gaaatttttg aaaatccaga
     4321 agatgcctta ggtcatggta tcaacataaa tggaactata tttgagataa taggtgtatt
     4381 ggatgattct cagcaaaacc aagctggagg attctttgga ggttaccaag atatgcaatt
     4441 tactacttcc cttataccta aaaaagcttt tgacacttta atgagtcaaa attcttattc
     4501 aaatgaaatt taccaattag acttagtttc ctctaaaggc tataatgtaa atgaagttgc
     4561 aaacaatgtt atatctaagt tatatgaaat gcaccctggt atcaatggtt cttatactac
     4621 accagaccca actgaacaga cagcttatct tgaaagcatt aattccaatg taaacaaata
     4681 tgtatctata ataactgtag ttgcaatgtt tgttggtggt attggtgtaa tgaatataat
     4741 gtatgtatct gttatggaaa gacaaagaga aattggtata agacgtgcta ttggtgcaaa
     4801 gcctaggtct atattatttc aatttttagt tgaagctgtt tttataacag tatgtggtgg
     4861 aattttagga actatagttg gatttgctgc tacaaactat gtttctaaat atataggctt
     4921 tgaagcaata cctagcttaa atagcttgtt ttatgcaatt atagctacta tattgactgg
     4981 agttgtcttt ggtcttatac cagcctttaa agcctctaaa ctagacccta taaaggcaat
     5041 ttataagtag aaattgtata aagattttcg atttttaaat tagtttatat aaaacatact
     5101 taaatatata acgcactatt atatatgata gattaataat ttaatctttc caaatataat
     5161 agtgcgttct ttcataaaag ggattctctt ccttctatat ctaaattacc aatatgtcat
     5221 accctaactg ttcaagctaa tatttccaat ttggattaat caatctcctt ttcctaatat
     5281 acaatctttt gctctcaaca attgtatcac ccaccttaaa aaaataatct taaattaggc
     5341 gttatataca atcttcccat tacatattgt ataattaatc ttgccataca aagatttacc
     5401 tttaaacggt gaattatcag ctttagaaac aaaactttca actgtccatt cttcttcagg
     5461 gttgaatata acaatgtccg ctacagcccc ttcttctata aacccagtat ttaaattgta
     5521 caattttgca gggtttgtag acattttttc tattaactgc atcatactaa gatgattttt
     5581 atgcactaaa tttgttattc caagagctaa ggaagtctca agcccaataa ttccacttgg
     5641 agcttttata aattctctat ctttttcttc tctactatga ggcgcatggt ctgttgctat
     5701 tatttcaata gtaccatcat ttaatccctc tataatttta tctctatccc atttacttct
     5761 taggggtgga ttcatttttg catttgttcc aaactccaat acatcttcct ctgtcaatgt
     5821 aaaatgatgt ggtgaagctt ctgcaactac atttgcacct aagtattttg caaatctaac
     5881 catatcaaca gatacacctg aacttatatg ttgtatatca accttagcac cagtctttag
     5941 tgccaacata caatctctag ctaccataac atcttctgct acacttgatg caccttttaa
     6001 tcctagttct gaagctatct ttcctgcatt tacacctgga tttccaacta aagaagggtc
     6061 ttcttcatga aaactaagtg gtacatctaa ctcttttgcc ttaaccattg cctccataat
     6121 tagattacta tccattaaag gtaatccatc atcagtaaac cctggtacac cagctttttt
     6181 aagagcttcc atatcaacta actctttccc ttcaaaacct ttagttatag ctgctgcttg
     6241 taaaacattt atacatgcat tttttgattt ttctttaaca taattaaaag tatcctcatt
     6301 atctacaata ggattagtgt ttgccataca tataacagtt gtaaatccac ctctagcagc
     6361 agatttagct ccactttcta tatcttcttt atatgtaaac ccagggtctc taaagtgtac
     6421 atgtacatcc actaaacctg gagcaactac attaccacta gcatctatta ttttttcata
     6481 ttcatcactt tcatcaaatt tacctatttt ataaatttta ttttctttta taattaagtc
     6541 aatattctcg tctctttgac ttttagggtc tattactcta ccatttttaa ttaaaatcat
     6601 attatttctc ctttatattt ttaatttata tagactcata taatattata cattatttta
     6661 catacttaaa tacaaaatta cgtttgacat caatagcctt tttaggacaa agttcatggc
     6721 aacagtaaca tcttatacat ttgcttaagt ctataatagc acccttagtc cctatttcta
     6781 tagtagctgc aggacaagct tccttgcatt ttccacattt tatacaatct tgaaatctaa
     6841 ctacaggttt tggtgttata agctttgaaa taggctcatt taaaaatttt ggtagcttta
     6901 cggaaaacaa tcttaaatct ttacttacat ttggaacctt gtaatttttt ataattaaat
     6961 cgtttatatc ttcacctaga atttcaatat ctgaaaaatc ttctcgtata taacctctct
     7021 taatagcacc tctaattgta gcaactctgt tgggaattaa acttataatc ttacacgcaa
     7081 caacgtctat agcatatgga ttttgtgatg ctaataaaac tcctatttct ctagtagtgc
     7141 cagctgaggg tccatcacct tccataccta ctataccatc cataattgtc aatgtcggtt
     7201 ttatataatc acaaatatct aaaagtacat tttcacaaaa caactcttct gtaggaaatc
     7261 tataatgtat ttctgctttt tttaatccag ctatacatcc atataagttt tttgtaccac
     7321 cagtaaaagt tgccattata tgagtcttta atttacaaag atttattatg taatctgaat
     7381 ctactactgg tttaataata tccatatatt ttagaacatg tgctttttca ctatgtacct
     7441 taacatctga aacatcataa tttaacttaa tgcccaattc atttgctact tcttcaattc
     7501 cagatgcctt ataaatactc ttaagagaac tttgattata tggaccacca gggctatctg
     7561 ctattgtaat atcacaattc aactctaaaa gtttttcaca tacaactttt acaaccatag
     7621 gatgtgtagt tgtagcttct tcaggctttt ttttcatcaa taaatttggt tttataagta
     7681 ctttactccc ttttttaaca aacttgtcta taccaccaat atcctctaaa tttttttcaa
     7741 tagataacct tacttcttca taattgtaag ttttacaact cctaacagat actgacttca
     7801 tattatctcc atccttctat cacaacagtt tatttgtata atttaaaaaa ggagaaacca
     7861 aagtttctcc ttttaatcta tgttttaatt attattttcc aaaatatctg tttaataatc
     7921 ctaagaatgc tttaccatgt ctagcttcgt ctttacacat ttcatgtact gtatcatgta
     7981 tagcatctaa gcctaactct ttagctctct tagctaattt taattttcca tcagttgcac
     8041 catattcagc atcaactcta actcttaagt tttcttttgt atctgcaact acaacttctc
     8101 caagaagttc tgcaaattta gcagcatgtt cagcttcttc aaaagctatt ctcttataag
     8161 cttctgctac ttctggataa ccttctctat cagcttgtct actcattgct aaatacattc
     8221 ctacttctgt acattcacca gtaaagttcg ctcttaatcc ttcaattatt tctgcatcta
     8281 caccttgagc tactcctatt ctgtgttcat cagcccaaac catttcgcct ttcatttctt
     8341 caaatttatc agctccaact ttacatactg gacattgtgc tggtgcagca tctccttcat
     8401 gtatatatcc acatactgta caaacaaatt ttttcataat taacttcctc ccaattttat
     8461 ataattaaat ttttattttt aagtttaata acttgctaca agaatatata taccccagac
     8521 tttgtagctt aaacactaaa aataaaattt atttcctaat taattttatc actttgaaac
     8581 aacagtatca accaagtttt gatgtcaaat ttctacataa tacataattt atttaattaa
     8641 ttaggaaata attgtaatat taaatacttt ccaatgaaga ctcttctgaa tctttaagct
     8701 tcactttttt gctctttaaa aaagataatt tggtttctgc agttatgatt gcaacaaata
     8761 tcaagatact accaataacc aattttgctg taataagttc ctttagaatt attatagaaa
     8821 atattgtacc aaatacagct tctgtggata atattatagc agttctagtt ccatcaactc
     8881 ttttttgaca tatcgtttga aataaaaatc caattgtagt actaaataca gctaggtaca
     8941 tagttcccat atagccagat aactcagcct ccatctttaa ttgacctgca aatgcttgaa
     9001 ctatcacaga cattaaaaat gctactgtaa attgaatggc tgtcaatgcc attggattat
     9061 tatcttttgc aaactcactc gtaaagaata tatgaaatgc aaatccaaat gaacatataa
     9121 gtgttagaaa atctccaaaa ttaatagaga aatcagcttc taaagaaagt atcccaattc
     9181 ctataagagc taccaagcta cttattatcc ctatcttatc aagttttctt ctataaagta
     9241 taaatcctat gaatggaact attacaacat tagctgctgt tataaacgca ttcttagatg
     9301 gtgtagtgta cataagtcca atagtttgta cggtgaaggc tagaaataaa aatattccta
     9361 aaatccctcc tgcttttaat aattttttac ccatattggc acgaatctgt ttaaaaaaca
     9421 gtaaattcat aattatagct gccaagaaaa atcttaaagt tataatttgt agaggtgtaa
     9481 gcccaccgtc taatgcaaat tgggttgcta caaagccact tccccatata attgctataa
     9541 atattagtcc tatttctcca aagtattttt tcaataaagc cccctccttt ttattttttt
     9601 gcaaaattat aaacccccta aacagcaaga gagtttttct ataagcatta ctataaatta
     9661 atatagtaaa ttttttcagt attttaaatc taaatttaca tatattttga gctcaaattt
     9721 atatccacca tttaacagta atatattaat cattttttgt aaacaccttt ttgataaatt
     9781 tttttgtttt ttatattttt ttacctatac taaatttttt tatagataaa tttgatatat
     9841 gtgatacttt aatattatgc aaataatgtc atataagtta cactttagtt atcttagtta
     9901 caactttgtc ggtttacttt ttctactttc ttcgatataa ttataatata tttttgatac
     9961 aattcgacaa aagggggaat gctgtaatta tggtaaaaaa aagaaaaaag aaaactgttg
    10021 cacttactat aattgttgta atagttattg gtattttttc tatggcatgg gcggacatgt
    10081 ctagaaaaaa agaaatgaaa gaaactcaag aaagacttaa agctgaaaga ttagaaaaag
    10141 aaagaattga aaaagaaaaa aatgaaccta ttattggtgc aaaaaaagaa gctataaaag
    10201 aatatggata tgatgcaaaa atagtttggg acaaacttaa caaatacgac tattcaaaca
    10261 acggagaaaa gatagtcttt cttacatttg atgatggacc atctactact aatactccac
    10321 aagttctaga tatcttaaaa agacatggtg ttagaggaac tttctttatt aaaggtgatt
    10381 ctcttgaaag aaaaggcgct aatgaaattt taaaaagaac atttgacgag ggaaatgcaa
    10441 tagcccatca ctcttatact catgactata aaaaactata tcctggcaga agtctaaatc
    10501 tcgatacatt cgtaaatgaa cttaacaaaa ctgatgaagc tatgaaaaaa gtcttaggaa
    10561 agaatttttc ctcaaatgtg gttagatgcc caggtggtta tatgtcatgg aaaaatatgg
    10621 aacccctagg aaactactta aaagagaaaa acatggcatc aattgattgg aatgctttaa
    10681 atgctgatgc agaaggtaaa aagaaaaatg cacaagaatt atttgaacat gcaaagaaat
    10741 cttctgaagg caaagaaatg gttgttcttt taatgcatga tacttatgga aaacaagaaa
    10801 cagtaaatgc attggaccaa attataacgt attttaaaga caatggttat caatttaaaa
    10861 ttttaatata gtaaaaaagc aagtttattg agtatacatt ttatactcaa taaacttgct
    10921 tttactttac tctattttac tagctctatt tttacaaatt ttttctttcc tatttgaaca
    10981 actaattcac tttcttttac aatagtgctt aagtcctcta ctttttcacc atttaccttt
    11041 acgccacctt gagaagctaa tcttctaact tcactcttac tcttaacaat ttcattaaca
    11101 actagtactt cgattaagtc aaatccatct tccttaactt gaattgtttg tatatcttca
    11161 ggtatttgac ctttttggaa tacagattta aatctttctt cagcttctct agcagattct
    11221 tctccatgat ataatgttac tatttctctt gctaagttca tctttatatc tcttggattt
    11281 acagaaccat cttttaattg agattctatt ttgttaactt catcaggatg aacatctgtt
    11341 actaaattgt agtatttaat tataagttca tcaggaattt ccatagattt ttggtacatt
    11401 attcccgctt cttcatctat tccaatatag ttacctaaac tcttactcat tttttctttt
    11461 ccatctaatc cttctattaa aggcatcatt attactattt gagactccat accaaattct
    11521 ctttgtaacg atcttcccat taataagttg aatctttggt cagttccacc aagttctata
    11581 tccgcttcta atgctataga atcatatgct tgcattaatg gatagaaaaa ctcatgtact
    11641 gatattggca tttgtccttc atatctcttt ttaaaatctt ctctttctaa cattctcgca
    11701 acagtaatag ttgctgctaa ttttattaca tcttcaaaat ttaacttagc taaccactca
    11761 ctattaaatc ttacaatagt tttttcttta tctaaaactt tgaaaatttg ttcttcataa
    11821 gtttttgcat ttgcaagaac ttgctctgtt gttaaagctt ttctagcttt agactttcca
    11881 gttggatctc caatttttcc tgtaaagtct ccaattatta ttactatttg atgacctaaa
    11941 tcttgtaatt gtttcatctt tctaagaact actgtatgcc ctaaatgtat atctggagca
    12001 cttgggtcta gacccaattt tactatcata ggctttcctt ctttttctga tttaataagt
    12061 ttttccctta actctttctc atctattaaa tcatctacac ctttcataat tattcgcatt
    12121 tgctcgtcta tcgatttcat ttttcattcc tcctaaaata tttatataat ctataatttt
    12181 tatttttata ataaaaaaag ctttcatcct attaaaagga cgaaagcatt gcttacgtgt
    12241 taccacctta gttcatcaat atctcacgat attaatctct tagagtataa tggcatatac
    12301 tcgtgtacta taacgtgtac tactccgata tctcttaatg gttgttatct ttcagagata
    12361 gtgctctgag atgtattcaa actaaatcaa tttattccat ttcaccaaac tggaactctc
    12421 tgttaaataa aatctagctc tacttcttct cttcatagca tttatatatt cagattattt
    12481 catcaattac aagaaatttt tcttaactta ctcataatat attattattt ttctattttg
    12541 tcaacctttt tattattata tacatgtttt tttacattat actacttttt tatatttttt
    12601 accaatacct aaagtttatt tttcaatcaa aagatttatc tgtttattga ctatattgtt
    12661 ctgactcaat cttatattta ttttcttatt taaaaatgca tttataatta ttaaactaat
    12721 gactgttaca tcaaacataa aaaacaacaa taaaattatt attaaaaaag aaattctagc
    12781 atataataat tttctaaact tagctattat aaaattttgt aatgacatac atgagtctct
    12841 aataataaaa tagacacata aatacgctat tgatatgaag actgttttta aataaacaaa
    12901 atcaacttta acgttcaaca gctttacaac ttcaaaaatg gttagataag aaacacatat
    12961 gtaaaaaact ttctttgaac aacataaaaa ttgatttaaa gttctaaaat tcttaaatat
    13021 taaaagcttt tttaaagaat tagaatctaa aatatgcaat ttattcccta aaatcaaact
    13081 taataaatat atgcaaaaca ccataccaaa aggaaacaat gctatcatta aataataaat
    13141 aaaatttgta tacccattaa aataaatcca tttgctatat ccttgaaatt ctttcataaa
    13201 actataacct attaatgttg aagcatatat atcaataaaa accattacaa taactccaaa
    13261 cactgatcca tatactaaat catccataac cattgtaggc ttatttatta gatagccaca
    13321 cattatacca agtaatacac tctgagttgc ccaaatagca gttcctaaat ttccaagtac
    13381 cagagaaatt attaaaagtg aagttattcc agataaaatt gtatacttta aatcacattt
    13441 caagcaaatt atacaaaaaa atattggcac tataaaatct aaataaatag catatccaaa
    13501 tccagtactc acagatataa ttgttactac tatgaataaa gatgacaata aagctgcttc
    13561 agttaatttt ttagtagtat tcaaaacgct acctccataa atcataaatt ttctaactaa
    13621 agttttgttt ttaatatagt atatcacttt ttaaaaatat ttttaataaa tataaatttt
    13681 aataaaggta tttatgttaa aaatgatata atgtatctta atattcagtt ttttaagata
    13741 ctaggaggta attattatgt ttaaaattaa acactttaat gatttaaatt tagatgaatt
    13801 ttatgaaata gcaaaatcaa gatatgaagt atttgcttgt gaacagaaga tattttcgtt
    13861 aaacgattat gatgatatag ataaaaactc ttatcatata ttcttaaagg aaaatggatt
    13921 gatttgtgct tatgctagaa taattcctaa agaatacagc tcttataatg atgtttccat
    13981 tggtagagtt ttagttcttt ctcgtcatag aagaaaaggt ttagcaaaac aaatgatgga
    14041 ttgtgctata gattttataa aagttaactt acacgaaaac aatataacct tatcagcaca
    14101 aacttatata aagaaccttt acttatcttg tggttttaaa gaaatctcag aagtatacga
    14161 cgaagcaggt attgaacata ttaaaatgag attatagtgt tgacaagcta atattgttaa
    14221 tatataattt aattataaat taaatattga attgatattt aggtatttga aaatacctta
    14281 catagagtca ggaggctttt gctttctggc ttttttatta tcaaaattca ataattatat
    14341 ggattcaaag tgttaatttt tattctatat tctactttcc ccaaaagtaa gaattatacc
    14401 caactttgta tgataggcat cttgcctatc ttttttttgt aaaagtaaca aggtgataat
    14461 ataatgcata gtttagaata agaagattag cccaggctaa attccaagca tggaggtgct
    14521 actatgaaaa accttaacga tattcaagtg aaaaaaactg tcaaagttga agatatatta
    14581 tctagtggta atttaagaga aagaatgtta gcgcttggtc ttactagagg agctgttata
    14641 gatgtagtta gaaaaggtcc aaaaaataat ttaactgtct ataaaatcag aggtagtaag
    14701 atagctctac gacaagaaga aagtagctta atattagtct ctgacattta aaaatttcta
    14761 gcaggaggat attaatatgg ggttaacaca taactcaact aaaatgagtt ctttaaaaga
    14821 tatgtttgat atagacaaca aagaagacca gtttgtaatt gcattggctg gtaatccaaa
    14881 tacaggtaaa agtactgtat ttaatcatct tacaggactt agacagcata ctggaaactg
    14941 gccaggaaaa actgtagcta cagctcgtgg taattttaaa cataaaaata ccgaatatgc
    15001 attaatagat ttaccaggaa catattcttt atttgcctta tcacaggaag agattgtagc
    15061 tcgcgatttt atatgttttg gtaatccaga tgcagtaata gtagtatgtg atgctacatg
    15121 tcttgaaaga aatttaaatt tagtatttca agtgatggaa cttacagata aagttatttt
    15181 atgcattaat ttaatagatg aagctataaa aaaaggcatt actattgata aaaaacttct
    15241 agaggattct ctttgcattc cagttattct aactgctgca agaaacgggt ctggtatgga
    15301 tgagctattg gatactttaa atgatgtatc ttttgacaaa tacaaattaa ataataagcc
    15361 tgttagatac aatgaaaata tagagaatgt ggtaaaatca attcaaccag aattggataa
    15421 tattataccg ggtataaatt ctagatggtt gggacttaga cttattgatg gtgatgaaag
    15481 tatatttgaa tctatgagta attatataga caaagattcc atagatgcta ttaatgaagt
    15541 aaagaaaaag attccagata atataaataa acagaaaata agagatgagt ttaccaaaat
    15601 caactatgat tatgctaaaa aactgagtga tgagtgttgt tctaatgttg ctaaaaaatc
    15661 aactgataga gaagaaaaag tagataaaat attaacatct aaaatatttg gacttccaat
    15721 aatgctctta ttattaggaa ccatattgtg gattaccata gaaggtgcta actatccatc
    15781 cactttattg tctaatttgt tactcggatt tgagccaagt atttcgggta tattaaatag
    15841 tattaattgt ccatcatggt taaatgatat gttggtttta ggattataca gaacattagc
    15901 atgggtaatt tctgtaatgc tacctcctat ggcaatattt ttcccattat ttaccttact
    15961 cgaggatttt ggatatttgc caagagttgc atttaactta gaccacctat ttaaaaaagc
    16021 ttgtgcacat ggaaaacagt gcttgactat gtgtatggga tttggatgta atgcagctgg
    16081 agttattggt tgtaggataa ttgactctcc aagggaaaga cttatagcta tacttacaaa
    16141 caactttgtt ccttgtaatg gtcgttttcc tactttgata gctatatcta caatattttt
    16201 tagctcagtt ataaccaact ctttcgtatc aagcgtagca actgcacttt gcataacttt
    16261 actgataatt ctaggtgtta taataacatt attagtttct tatactcttt ctaagacact
    16321 attaaaagga gttccatcta cgtttacatt agaacttcca ccttatagag ttcctcaaat
    16381 aggaagaact ttatatactt ctataataga tagaacaata tttgttttag gaagagctgt
    16441 aatggtagcc atacctgctg gtgtcataac ttggatattt gcaaatatat atataggaga
    16501 tttaagcata ttatcacatg ttgcaaactt tttagaccct ttagctaagt taattggtct
    16561 tgatggtttt atattacttg cttttattct tggattccca gcaaatgaga tagttgtacc
    16621 tatactttta atggcttacc tagcaactgg ttctatgata gaattagata gctttagtgc
    16681 tttaggtcaa gttcttagag aacatggatg gacttatttg acagctttaa atgttatgct
    16741 gttcagttta ctacattggc cttgtgcaac aacactttta acaataaaaa aggaaactgg
    16801 tagtttaaaa tggactgcct taggattctt aatgcctact atacttgctt ttgttgtttg
    16861 ttttttaaca actacagttt acaatttatt tatataatta acattaactg acattagaca
    16921 tatattagaa tactttatta taaagcatag agatatattc aatgataagt aaaattactt
    16981 agtatttgga tatatctcta ttttaactct tatctggaca cttggattga aatttcagtc
    17041 atataattat cttcattact ttcacaaaaa aagtcaagta tactctcttc atatgaattt
    17101 ccaataattt tatattcatt ttcatatata tattttttca atttttcata agatttatat
    17161 gaattctcat actttccaat atgctttatg caagcataca ttccttctgg ctttatatat
    17221 aaccttttat cctttatttt tttatctatc ttcaaataaa aacttgatat acttaaatag
    17281 tccccatttt ttaggttttc attacttact attactccta actcatatcc ttgatataaa
    17341 ttcttcgctt tacaataatt ggtgaaatct attaattcca tcataaaatc accattactc
    17401 atattactca aatcacttga taaaactaaa tattcttcag actttttgga tatataaatt
    17461 tcttcactat tcattttaga aattccttcg actgttatat ttattctatt ttgcatctta
    17521 gaacttatct ttcgtaattt ttttattttt tctcttatct ttttttcttc ttctttaagc
    17581 attttcacac aaagctgagg agttctattt tgtatatact cttttatttc ctctaaactc
    17641 attcctattt ctcttaatga ttgtaatata tccaatgtat catattgata aactgagtaa
    17701 tatctataat tatttttatc tttatattca ggagaaaaaa tccctatttt atcatagaaa
    17761 attaatgtct gtttagatat accacacaat ttagcaaatt cacctgttgt aaaatactgt
    17821 ttttccaagg gttatgcact ccttttattt ttattatata tatagttact atatacttta
    17881 gtatttacta aatcaagtag ttattatttt agaaaatcaa tatgtttttg attttaaaga
    17941 ttaaatgtca gttaaatatt ttatccatcc cagtaataaa aaatatacac cctctgaact
    18001 tttagatatt atatttatgc ttgttagagc ggaaattgta aattgtatct acctcttact
    18061 attttattta tgatatatta ctttttaatc taaaaagaga tatctatttt tattctagtt
    18121 atctcttttt agattccttt aagcatatga atattccaat ttaacaccta ttgaagtgct
    18181 attttcttat atcacaattt ataattgata tatcttcaat ataataatct aatgtatttt
    18241 tgattttaaa gcttttcagt aatattattg ataaattaga attaattatc tagctttaaa
    18301 aggtcaaaaa tttcagttgc cgtctgtggt tttccaaata aatatccttg tatgtaatct
    18361 ggcttcattt gtttaactaa atcatactct tcttgtgttt ctacaccttc taaacatact
    18421 tttattccta catcatgaca aattgcaaca ataaaatgta taaatgtagc atcaaactta
    18481 ctctttaata tatctttaac aaatactcta tcaattttca ctacatctat tggagaaaat
    18541 tttaaaactt ctaaagacga atatccagta ccaaaatcat ccatagcaat ataaattccc
    18601 aaatcttgta aagccttaaa cttaaactgt aaaatactca tattttgtac tgtatgactt
    18661 tctgtcaatt ctaaaacaag attttgataa ggaaactttt catcatctat gatttttact
    18721 atatcttcaa taaatgtatc ttctaatatt tgaacagctg aaacgtttac actcacttta
    18781 aaaaaaggat aataatcaat taatccctta aaagtacgta acgccattct aagcacccat
    18841 gctcctacag tatttatcat atcatgttct tctaatattg gaataaattc taagggagaa
    18901 attgctttat atttatcatt agtccatctt aaaaggactt ctacacctat tattttatga
    18961 ctttgtgtat ctacttgtgg ctggaatcga agactaaatc ccctaaaatc atcattaatt
    19021 gatgctttta aatcccgcat catttctaat gaatacattt tattttttaa tatttcttgt
    19081 gagaaaaaaa caagcctgtt tttaccatgc tcttttgcat attgtaaaga gtaactagca
    19141 tatttataaa gttcttttac tgtatctccg tgctttggat atattacaca accagcagaa
    19201 attgttatat ttaatccata ttttctccat agttgaaggt gtataatcat attctgtatt
    19261 tgattgtata aagttagaat ttctttttct tcaacattat caacaataat tcccatttca
    19321 tctccatcaa gtttataaag ttcagcatta tctggtaata tagattgtat agactgtgct
    19381 agtgttttta ttatattatc tccaaaatct ctatcataca tctcattaac atttttaaaa
    19441 tcatcaatat ttaataatac tatgcataat ttttcaatca taggatttga aattttatct
    19501 tcaaatacac tcataaattc atgatagttc aataactgtg ttaatgaatc aatcttattt
    19561 tgtttaccta attgtgtcat tattcctgca aaaatacttg gttttccaaa ttcatcacgc
    19621 attagttgcc ctctacatct taaccatata tattctccac tgcgattttt agccctaaat
    19681 tccactgtat gatagtccat ctggttttta cctatttcag tatttgactt ataaaaacgt
    19741 ttccagtctt ctggatgtac aattttttcc cagtaaataa gaggattttc aacaatttct
    19801 cctggtaagt caaataattc aacttgtgat ggtgaatatc gaaatactcc tgttttcata
    19861 ttacaaatat atatatattc atctgtacct ctaatcaaag catcataaag caatgtagaa
    19921 ttataatcaa aattgtctat tgagacatta aaaactcctt tttcttcttc agtatttgat
    19981 attttatgaa attcattagg cttaatttgt ttatttaagc ttgttgagtt tgtaatatct
    20041 attgattggt gcatatgaac aactgtgcca tcttgccatg taattaaact atcataattt
    20101 tcaaaaacac aatttagctt attacatttt tcataccatt ttattaatac tcctttttta
    20161 tcattcttta acaattctac aactttacaa aaactacaag tagaattttt ttcaggatat
    20221 aatacttgcc aacaaacttt tccttctgga tctaaaatgt tatattcttc tttcattttt
    20281 ttattcataa aaacaatttc attagtatga atattcgtaa catatatgtt aatctgtagt
    20341 tgatttaata taacttcaaa attatgtttg ttcatatact tatctcctcc atagttattg
    20401 ctctttataa caacattgtt aaaattattc tttccagaag atttacttat aatttata
//
LOCUS       DAMKOJ010000063        19550 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.068, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000063 DAMKOJ010000000
VERSION     DAMKOJ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19550
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.068"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(73..639)
                     /locus_tag="PC592_002585"
                     /pseudo
     CDS             complement(73..639)
                     /locus_tag="PC592_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
     gene            complement(711..1700)
                     /locus_tag="PC592_002586"
     CDS             complement(711..1700)
                     /locus_tag="PC592_002586"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDF4056538.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDAFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDNKKAYNLVKDKKILLELCPTSNVQTKTVDSYETHPFYTFYKDNLHVSINT
                     DNRTVSDISLSSELNVIFDTFKLGIEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            1960..3213
                     /locus_tag="PC592_002587"
     CDS             1960..3213
                     /locus_tag="PC592_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HDF4056539.1"
                     /translation="MITLTFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYNLKPSSNIDLSVPTYNRNLNRFGSKFFRNK
                     NMVKNNNFSQTITPSVFLEQVLLIFICINTGEIISRCFYIMFNILLPSVVTCMFSAVL
                     FRNLNDKISILELNFKLIDFLKEISLGIFLTLSLMNIDLFELSTLLPPILLIVIFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGNSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            3310..3534
                     /locus_tag="PC592_002588"
     CDS             3310..3534
                     /locus_tag="PC592_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF4056540.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(3990..4232)
                     /locus_tag="PC592_002589"
     CDS             complement(3990..4232)
                     /locus_tag="PC592_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056541.1"
                     /translation="MYLNKESLIYRNEEVTKMKIGNINGQAPITNGLDSCQSEVQGLE
                     QKKKALQDEIEKVRSDKNIDSETAKLKIEDLRKQIE"
     gene            complement(4271..5629)
                     /locus_tag="PC592_002590"
     CDS             complement(4271..5629)
                     /locus_tag="PC592_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF4056542.1"
                     /translation="MINLFASDLFLKYSFLFSFTIYRILMVIVQYYFLINFTNVNSKF
                     WCFILYSIISIFLIIISTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSTVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMALSSLITIIIAGFVYWYSSKKFNI
                     KVMNFDKYLAILIIPLLLIILFMQSFKHSSNINIDTSLGTVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQSLEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKGQILKAQDYLNKLEKVTSDLSFSCNTRNVVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPKSTNMNDFDLCIVFANAIDNAIKACRVVDKQSRYLKISTKLEGGFF
                     MIEIKNSYNPINNYTSGSCIGLSNIKEIAKKYQGAISIDKTSDYFQINILLVISLHCA
                     GI"
     gene            complement(5631..6362)
                     /locus_tag="PC592_002591"
     CDS             complement(5631..6362)
                     /locus_tag="PC592_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056543.1"
                     /translation="MTRKKMYILISIAICDDESYMLNHLKENIELYMKQNNLSYNIEL
                     FDKAEDLLCNHEKFNIVFLDIQMEDINGMQTARELRVYGNDCFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLEDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETIDYYETIENLERSLPTNFFRCHRSYIINLKYVYGYESGNAVMESGD
                     RIPISRLRQQIFSKVMLEFMKNRRR"
     gene            complement(6651..7958)
                     /gene="grdB"
                     /locus_tag="PC592_002592"
     CDS             complement(6651..7958)
                     /gene="grdB"
                     /locus_tag="PC592_002592"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(6909..6911),aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF4056544.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEENPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVVTGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVNYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEAIEEQTVFE"
     gene            complement(8035..9321)
                     /locus_tag="PC592_002593"
     CDS             complement(8035..9321)
                     /locus_tag="PC592_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF4056545.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYINSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            complement(9600..10922)
                     /locus_tag="PC592_002594"
     CDS             complement(9600..10922)
                     /locus_tag="PC592_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF4056546.1"
                     /translation="MKILIVDDELEYGVVMKKILQKKGYLVDVTLSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKAINKDIEVILVTGYGSIENAVDAMKKGALSYFIK
                     SNPIENLLEEVEKVKTSKTSVSLQKNNLEFTLESKNRDFNDVIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLATLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIKP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKIAEYNIK"
     gene            complement(10922..12916)
                     /locus_tag="PC592_002595"
     CDS             complement(10922..12916)
                     /locus_tag="PC592_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF4056547.1"
                     /translation="MNKKRIVIIGIIYSFLVIFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIVVDLINSLSIQIGRDFYFKP
                     NNWWKESFINSIDDSIKFFDLIPSKERASKFIFTDPIYTLSANILKDKKSEDINSYMD
                     LKGKTVAIPEGDYSINFLKQKVQDINILLTPDIKTGVNHLISGKVDAVVGDEPVLRYY
                     INNYGISNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEEVMENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDVMGEMSYKIADLIDMIKGVIENTFSENTN
                     KTSEIEVHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKILQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALRDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNREVTI"
     gene            complement(13003..14250)
                     /locus_tag="PC592_002596"
     CDS             complement(13003..14250)
                     /locus_tag="PC592_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF4056548.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMATGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALLSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILFAMLGGGKAGNIISPNPNT
                     IAVSGNFSVNLSSVMIANIIPAIVGVIITVILASILINKGNKVQSYEILEKREDLPSL
                     FKSLCGPIIAIFLLFLGNVFPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIAALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIINSGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            14468..15013
                     /locus_tag="PC592_002597"
     CDS             14468..15013
                     /locus_tag="PC592_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056549.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHNNRKKVILPGSKNVVYEILIPDSS
                     GNLEFAIMNLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLFKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            15027..15713
                     /locus_tag="PC592_002598"
     CDS             15027..15713
                     /locus_tag="PC592_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDF4056550.1"
                     /translation="MKTYKFIFFDADDTLFDFRKSESHAFKKLLSEFNLELNFENYIK
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKINLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILPYLKEKYTIVIITNGIYEVQKKRLENSRIKGYIDGIVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMVGDSLTSDILGGINSGIDTCWLNSNNNINYTNHIPTYEI
                     NTLLELNKLL"
     gene            complement(15837..16457)
                     /locus_tag="PC592_002599"
     CDS             complement(15837..16457)
                     /locus_tag="PC592_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056551.1"
                     /translation="MNYNSNKDKFILADINLADIFIDKNIVLKFLGYGNRKAPDTISE
                     IVEREIRNINDILDIKIYISEVNIDKTPKECKKAFAVMYTIGDKIDIKMNDYMKNCNM
                     MAGLALDKIGIVCLDCINEKIKMYLKEKYDSLKISHEIYPGDKEFEVERQKDIYNYIK
                     NKYSSVEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(16447..17469)
                     /locus_tag="PC592_002600"
     CDS             complement(16447..17469)
                     /locus_tag="PC592_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDF4056552.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDREKLRKL
                     DVPDPYTSGRMPLNIESLSLISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEYIVKNLNKIYDEL
                     DCWKGMHICGDTRELLDNMLDCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDINEL"
     gene            complement(17470..18108)
                     /locus_tag="PC592_002601"
     CDS             complement(17470..18108)
                     /locus_tag="PC592_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF4056553.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINILKKTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNRIKVDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(18235..19386)
                     /locus_tag="PC592_002602"
     CDS             complement(18235..19386)
                     /locus_tag="PC592_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4056554.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIPYEIVEFDETNF
                     EKDDDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGTIAYNKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     IKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDSELLKYMEFKQVENKYIIKYKEEELV
                     IESLDKLNKLFFEKNEEQYNEFKHLKNIYKFATKAFPVDFPWTANLNYQ"
BASE COUNT         6441 a         3222 c         2010 g         7877 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaagtcac aagtgtgcgt
       61 agctattttt taatcaaaat cattgatgtc ttctggtaga ctacttacat attcatccca
      121 gttatttatc aatttaaaag ttttatttat atgctgttgg ctagaaaaag ccaactgtaa
      181 tatgtttaat atataaatcc tttctctata atctttaaca tcatatccat atattgaagc
      241 tacatcatat agaaatttta ctttaatacc taaaagtaaa ggaaaatcag ataaacctaa
      301 gaggattcct cctgcccctg ttcctgctcc ttcaatcatt gctgtggtct tgtatgtttt
      361 agctttttct aaaactaatt tttctctttc ttctaatgac atctttctaa gtggtggctt
      421 tgtggcatat ttatatccaa acaatacagt ttttgtcatt acttttatag aagaagtaat
      481 tatttcatga tatttatctg gcaatactcc attaaactta ttctgtatcc cctttgatgt
      541 tttgtcaaat atagaaggtt tctttaatat atttttcttc cattcttcaa gttctttttt
      601 gactagttta atataaacaa catctttata atctttcaca ttttttctcc taatacaatg
      661 tatttttgtc aatttaatag cttaatttaa agtttatata tttttatcta ttaaattaaa
      721 ctattcaaat actctttagt ttctttgtct gcaaaactag cttctactgc atttctataa
      781 attattttat agtcttctat tcctagttta aaagtatcaa atataacatt tagttctgaa
      841 cttaaactta tatctgatac agttctatta tcagtattta tacttacatg taaattatct
      901 ttataaaaag tataaaatgg atgtgtttca taagaatcta ctgtcttagt ttgtacatta
      961 ctagttggac ataattcaag caatattttt ttatctttaa ctaaattata agccttttta
     1021 ttgtctttaa tttttacccc atgaccaatc ctatccgcct ttaaaatatt tatagcatcc
     1081 aatacatttt ctccacttgc agcttctcct gcatgtattg taactttata accatattct
     1141 cttgctaatt tgaaagcatc tttatattcc ttacaaaatc cctctttctc tggaccacat
     1201 aagtctactg ctacaacacc tttatttaca aatgatttcc cttcttcaat tactaataat
     1261 gcctcttttg aggtcattgt tctcatacaa cctaatatta aattgccttt tatatcataa
     1321 atactttcag cttctctaat tccttcaatt ataccctcaa ttatattttt aacactcata
     1381 cctttttggg tgtgaagtaa tggtgcaaat ctaatctcaa tatattttac attttctcta
     1441 cttgcatctt ccaaaagttc aaaagtaatt ctttttaaat tttccttaga ttgcattact
     1501 tttaaaggta aatcaaattt ttctaaatat tcatcaagtg aagtacaatt aaaagaaacc
     1561 tttgctaatt tttttatttc atccatatta tttgaaggta aatctatttt ctctttaata
     1621 gctatatcaa gcatggtttc tactctaaca cttccatcta agtggcaatg taaatctatc
     1681 ttaggtaaat tttcaaacat tttatcctcc tactgtactt ataaataata ctatcaacag
     1741 atttttaagt cttatttcta ttatatcaat atactacgat ttttcattct aaaaaagtca
     1801 catctcatta aaatatttta atttaattta tgactatcta attatatcta ctgattcttt
     1861 ttaatataca tttattaata tacatttgat aataaaattt caatacataa aaatttaagt
     1921 tatataatta aaactttaaa ttacaaagga ggacttattt tgattacctt aacttttgat
     1981 atagtgcaaa ccttgacact atctatattc ttctttttaa ttggtaattt attgaagaat
     2041 aaagttaact ttttaaacaa tttctgtata cctgcaccag taataggagg tctattattt
     2101 tgttttctaa atttattttt taaatatttt aatatagcag atatatctat aagtggaaat
     2161 ttaatgccaa attttataac cttctttttt acaactatag gacttgaaat aagtataaat
     2221 cttataaaga aaggtggtag tgtattattt agatattgga ttttgtgtgg agtattggca
     2281 ttttgtcaaa atatcttagc tattacaata tcaaagatta taaaacttga acctctttta
     2341 gggcttatgt gtggaaatgt atctatggaa ggtggtcatg gttattctgc tgcatttgga
     2401 cttacaatag aaaatcttgg tatagaagga gcagttggag ttggcttatc tgctgcaaca
     2461 ataggactta ttatgggtgg tatattggga tgtcctgtag ctaaatttct aataaataaa
     2521 tataatttaa aaccatcatc aaatatagac ttatccgttc ctacatataa tagaaatcta
     2581 aatagatttg gaagtaaatt ttttagaaat aagaatatgg taaaaaataa taacttctct
     2641 caaacaataa caccatctgt gtttttggaa caggttcttc tcatatttat ttgcataaat
     2701 acaggagaaa ttataagtag atgcttctat ataatgttta atatcctatt accttctgtt
     2761 gtaacttgta tgttttcggc tgttcttttt agaaatttaa atgacaagat aagtatacta
     2821 gaattaaatt ttaagcttat agacttttta aaagaaattt cattaggaat ttttttaact
     2881 ttatcactta tgaatataga cttgtttgaa ctatctacat tattacctcc aattctctta
     2941 atagtaattt tccaggtaat ctttataatc ctattttcaa tatttatttg ctttagagta
     3001 cttggaaaag attttgattc tgccatcata ataagtggtt tgattggaca tggaatagga
     3061 gctactccaa acgctttggc aaatatgagt tctttgacac aaaaatatgg aaattcgcca
     3121 aaagcatttt tggttgtacc attggtaagt ggttttttgc tagatgctat tagtatccca
     3181 tgcatacttt tttttataaa catactaact tagtatgttt attttttgtt atatattgac
     3241 aatttgctct ttttgttata tattataaat ataaagtttg ataatgattt tcattaggag
     3301 gtgttaataa tgactgttta caacttgaaa cttggacaaa agggaattat agacaatata
     3361 gctggaaatg aaaaacttat gaagagactt ctagccttag gattaataga tggcactgaa
     3421 gttgaagtga aaaagatagc tcctcttaat gaccctatag tgattagatt tagagggttt
     3481 gacttagcta ttagaaaatc tgatgcaaaa aatataaatt taaaaaataa ttaataaata
     3541 aaaaagagat tttagaatct ctttttttgt ttatgtatag ataaatgtga ataaatattt
     3601 aagcattata taccatgtaa aagttatcaa gatagacttg taaataatag ttataaaacc
     3661 acctataaat gtactaactg taaataaatt gtgtattcta ctaaaaaatg ttgataatta
     3721 aaatatcaac tatttttata aataaactat ataggcctat taaattttac ttttaagttt
     3781 ttatcatctt gaacaacatg ataagtatta tcccattgtt cgtctgcatt gtttctttca
     3841 aaaacatcat ataattgttt tacattttca ttattagaag gttctttttt tctgtctaat
     3901 agattattat ttacttctga aacgttattt tcttctttat ttgtttcttg tgctttatct
     3961 ccttttaact cttgaatttt actttcaatc tattctatct gttttcttaa atcttctatt
     4021 tttaatttgg ccgtttcact atcaatattt ttatcacttc ttactttctc tatttcatcc
     4081 tgtaatgctt ttttcttttg ttctaagcct tgtacctcac tttgacaact atctaagcca
     4141 tttgtaattg gtgcttgacc atttatattt ccaattttca ttttagtaac ctcctcattt
     4201 ctatatatca aactttcttt attcaaatac ataatatagc ttataaacac tattttcaat
     4261 gaaattgttc tcaaatacct gcacaatgta atgaaataac taacaatata tttatttgaa
     4321 aataatctga tgtcttatct atacttatag ccccttgata tttcttagca atttctttta
     4381 tatttgaaag ccctatacat gaaccacttg tataattatt tattggatta tagctatttt
     4441 ttatttctat cataaaaaat ccaccctcta atttagtaga aatctttaaa tacctacttt
     4501 gtttatctac aactctgcaa gctttaattg cattgtcaat agcattagca aatactatac
     4561 ataggtcaaa atcgttcata ttagtgcttt tgggtataat tacttcacaa tccacctcta
     4621 tgcctaattg ttttgctata cttagtttat tgttaaaaag agcatcaata acaacattcc
     4681 gtgtattaca agaaaatgat aggtcacttg ttactttttc aagcttattt aaataatctt
     4741 gtgcttttaa aatttgacct tttttcaata atccattgac aatagctaaa tgattattaa
     4801 aatcatgcct aaaggatata gtttgtgata atcgtgattt cgcttcttca atatagtttt
     4861 tttgagcatg aatctgttga ttcataattg ccctctcctt gtcatcttcg agagattgaa
     4921 ttagtttctt aaaggtaaat aaagaaaaaa atacacatat agttccaatt atagaaaaaa
     4981 gaaaagcttg aatttcttca gttatagaag tatttaatag caactttaca gtaccaagac
     5041 ttgtatctat atttatattt gaactatgtt taaatgattg cataaataat attataagca
     5101 acaatggaat tatcaaaatt gctaggtatt tatcaaagtt cataacttta atattgaact
     5161 ttttagaact ataccaatat acaaatccag ctattataat ggtaattaaa gaagatagtg
     5221 ccatatttat atcaaattta taaatatctg tatttatatc actagtaaat atcaagtaat
     5281 ttaatggagc tgtaaatcca tatactaatt gttcaattaa atatactaat aaggttgata
     5341 ctgtagataa aacagtagat tgttttatta tgtactttac aaataaaaaa gtcataagaa
     5401 aaaatagaat ctgtgaagaa aataaattat ataaattaaa atatgtactt atgatgatta
     5461 aaaaaattga aattatcgaa tataaaataa aacaccaaaa ttttgaatta acatttgtaa
     5521 aattgattag aaaatagtat tgcacgatta ccatcaaaat tctatatata gtaaaagaaa
     5581 ataaaaaact gtactttaaa aataaatcag aagcaaataa attaatcatc ttatctcctc
     5641 ctatttttca tgaactcaag cataactttt gaaaatattt gttggcgtag tctagaaata
     5701 ggtattctat ctccactttc cataactgca ttaccacttt catatccata tacgtatttt
     5761 aaattgatta tataactacg atgacaccta aaaaaatttg ttggtaaact tctctctaaa
     5821 ttttcaatag tctcataata atctatagtc tctttcttta aatgaacata aatctttctt
     5881 tttataactt cacaatataa aatatcagca agttttaatt tccaatatga ataacctttt
     5941 tgtattgtga tataattact ttcattatcc tcaagttttg taactatttt atccaaagtt
     6001 ttatatagtt tctcattaga tagaggtttt atcaaataat ttatagcatc tacttcaaaa
     6061 gcatcaaata caaattcatt taaaactgta acgaaaatta taaaacaatc attaccatat
     6121 acccttaatt ctctagctgt ctgcattcca ttaatatctt ccatctgtat atctaaaaat
     6181 acaatattaa acttttcatg attgcatagt aaatcttctg ctttatcaaa aagctctata
     6241 ttatatgata agttattctg cttcatatat aattctatat tttcttttaa atgatttagc
     6301 atatacgatt cgtcatcaca aatagcaatt gaaatcaata tgtacatctt ctttcttgtc
     6361 attattctaa ttattatata aagttaattt tttctgttca attaatatgt tctagtatgt
     6421 tgaatatttg ttccaaaatg taataagctc acttttcata gtatatctaa tttaaattta
     6481 tgtatcaata ttataataaa ttaatttatt atttttataa atttaattta aaaatgtaca
     6541 aatagtattc aatatttcga atttatctaa caaaaaaagg tatcgtaaaa caattttaaa
     6601 aaactatttt tcgatacctt ttttaatttt aatgttgtgt tatattttta ttattcaaat
     6661 actgtttgct cttctatagc ttctgttagt gcatttaaag cttttaaaac tatattcttt
     6721 ctaatttttt tactttcctc ttctcctaac ataggatttc caagtggata tggtatccct
     6781 actgctggaa caattctatt agctcctatt gtaagtgata ttggtactac tgtacatata
     6841 tgaacaactg ctataccagc tctctcaatc tcttttacca tcgttgctcc acaacgagta
     6901 caagtacctc atgtagaagt taaaattaca gcatctacat catcttctaa caatttctta
     6961 gaaaactctt ctccaaatct tttagaatta ccaacactcg ttcctgttcc tgtagtagtt
     7021 ataaaataat ttactaattc tccaattaca ccttcttttt caagttctct aactacatct
     7081 agtggtacaa ctaaatttgg attttcaaga acatatgctc tatcataccc accatgtata
     7141 gttgtaaatt ctttatttga catagaatcc atatctgtta aatcataaat tccatattta
     7201 gtagcacttg aagattcaat tttatctgga ttatcaattg gaactatacc tccagaagtt
     7261 actagtgcaa gttttatctt agataaatct ttaacaggtt tcataggtgt aactctatca
     7321 aattcaggca ttggatactc agtttcaaag ctttcacctt tcattttctt aactaacata
     7381 tcaattgctc tttcagaccc tctaagctca tggaagaaat tctttcttat tcctctcatt
     7441 atatatcctt cttcttcagg aggtcctatt tcctcacctc taaccaattt aagacctagt
     7501 ttcgtcatta ttggaactac ctttctaaga cttgctgctg aatttcctgt agatactata
     7561 tgcaaatcta acttaaacat atctacacct ggattttctt tatacattcc tgtaactaca
     7621 ggaatattta gctcttcttc aactgcctta caaatagtcc cacaagctac tccatatcta
     7681 cctgcattaa atgctggacc tgcaataaat aaatcaggat tttcttcttt tatcattttt
     7741 aaaagttctt gagttgcact ctcaatattt tcaccaaaat acgtatctcc acaaattaca
     7801 gttgagatta tctctgcatc atcattaaat tgactctgaa atgctattcc aggtcctact
     7861 acaccagccc ttttttctgg cggaatatct gctttttcct ctccacctat accagcaaag
     7921 aaattgttta tataatgaac cactctgatt ttactcatct tttaaccctc caaatcactt
     7981 tatagttatt acatcaatga ttacaccaac agaactttat attcaaatgc ttatttaata
     8041 atatcttgct gtcaaatgat tatagccatt tgctatagtt gatgctatta taatttgtaa
     8101 ctctgcatcc atgcttccat cttcatttaa gcatccttta tacccaccta tcatcatttc
     8161 aacatagtct aaagttccta taattttttc cattgctggg aaatgaacca ctagatttcc
     8221 ttgaccacaa gaaacaactg catctgcttc cttagtagca tctgctatag attgactctt
     8281 gccatctttt ccaggaaatt catctgttat caaaactaca tttgctccaa cttcactaca
     8341 ttttctacaa ttcatcatta ggtcagtatc tggatttcca taaccttctt ctgtcactag
     8401 aactccatca actcctaaaa attctattaa tttagctacc atatcagagc ttctctcttt
     8461 atcaactaaa aatacattct cattagtcaa aataactcct ataaagttta aatcttttcc
     8521 atgtctttta tataagtcat gtataactgg attatttaaa tgatggaatg tcgtaacctt
     8581 atcacatggt gctacacagt ttccagatat tatagctcca tccattattt cagttggata
     8641 cataaatgta ggaactatct gtttagcatc caccccgtag taataagtat catgtaaaag
     8701 tccttgtgat tgtaacatat gaacatatgc tactgttggc aggtctggat attcttttac
     8761 ttgttttaat aatggctttg tctcatatac aatgacttca tctggctcaa cttctcttcc
     8821 tgcttcgcct acgtatgcac ctatttttaa tccagcaatt ctagctgctt cttcataatc
     8881 atgagtatct ataccatcct ttgcttttat aacaatacat atattatttg tttttgaaaa
     8941 aggtgtatat ttagcagtag gaccactcat atcaattacg ccttcttgaa atccaactat
     9001 atttccacaa gttacaacac aagctcctaa aagtacatgg gttcttccac ttcctacagt
     9061 cttcacttta tttataattc caggaaatat tttgctttca tctccaattt taactctagg
     9121 ttctattaca tctttaactg gagctattct tattgattcg ccaggtcttg caagttcaac
     9181 atttacactt acaatccttt catcttctaa tactattttt tctatttctt cgctattgat
     9241 atatagtacc ccatctttta cttctgtctt ttctccaaat tcaacatttt ttataaatat
     9301 attccctagc tctagcttca tatgaaaatc ccccttaaca tatttaatcg caattaaaag
     9361 tatttattac gtttattaat gtatgaagca ttttctatgc caactattta aaatatatat
     9421 tctatgtatt aatgtcatag aaatttgcat ttttaattta catcagtatt gaatttacca
     9481 ataatcattg taaatattaa tttttaaaat tataataaaa aaagataaac agattttttc
     9541 tgtttatctt ttagtacagt ttgagaaatt tttttctcac ttaatgagaa gtttttttct
     9601 cacttaatat tatactctgc tattttattg gttaactgtc ttctactaat ctccaatttt
     9661 ttagctgtat ttgaaatatt atttccacat aaagataaaa ctttttcaat atactcacat
     9721 tcaaactctt ttcttatttc tcttaaaggt ttaatactta ttttatcatc tatatacaca
     9781 ttatttgata ttaaatttaa attatctttt gatagattac cttcttcgct taaaactaca
     9841 agtctattta ttatattttt tagttctctt atatttcctg gataattgta atttaataaa
     9901 aagtctttta cttccttatc aattgagtgt atctttttat catgttctat ttgatactta
     9961 tttaagaaaa attctataag agtagctaag tcttctcttc tctttcttag tggtggtata
    10021 gttattgtta tcgtacttat tctataaaaa aaatcttctc ttatatttcc atttgatatt
    10081 tccacttttg gttccttatt catagcacaa attaatctaa agtcaacttt aatagattta
    10141 ttgcttccta tcctctctat agatttgtcc tcaagtgtcc ttaaaagttt tacctgaaca
    10201 tttaaaggta tatctcctat ttcatccaaa aataaagttc ctttattcga aagttcaaat
    10261 ctaccttttc tactatctac tgctcctgta aaagaacctt tttcatgacc aaataactca
    10321 gactccaata gattttctga aaaagagcaa caatttacag gtacaaatat ctcattcttt
    10381 cttggactta tgctatgtat atatctagct aatatatctt ttcctacacc agattcaccc
    10441 aagattaata tattaacatc tttacaagca gctttttttg ctatttttat gacatcatta
    10501 aaatctctat ttttagattc caaagtaaac tccaaattat ttttttgtaa agaaacagat
    10561 gttttacttg tctttacttt ttcaacttct tctaataaat tttcaatagg attacttttt
    10621 ataaaataag ataaagctcc ttttttcata gcatcaactg cattttcaat acttccatac
    10681 cctgtaacta atataacctc tatatcttta ttaatggctt taattctatc taatagctgt
    10741 actccatcca tatttttcat cataacatca gataaaacca aatcataatt tttatctttc
    10801 ttaattatat ttatagcttc ttcaccactt agtgttacat ctacaagata gcccttcttt
    10861 tgtagaattt ttttcattac tactccatac tctagctcat catcaactat tagtattttc
    10921 attatatagt cacctctcta tttaatggaa tttttatatg aaaacaagtt ccaaccccca
    10981 atttactttc aacacttata tcgccattat tctttttaat ctcattataa gtaatgtata
    11041 aacctaaacc agttccctca ccaattggtt ttgtagtata gaaaggatta aatatatccc
    11101 ttagagcatc ttcttttatt ccttccccat tatctttaaa gtctataaat aaacaatgat
    11161 ttttttcata gcaatatata ataatttttc catcttgatg tattgcatct attgaattag
    11221 aaattaaatt tataaataca tgttttaatg attctccatt tatatagcaa actaaattat
    11281 gttcacaatc aatttttatt tcaacattct ttaactgtaa tattttatat tgaagtttca
    11341 ctatattttc aataaaattt cttatattta tatgttctaa attatcatct gatattctcg
    11401 caaaatttaa caaattagtt attatgttac ttgccctatc tacattactt tctattgatt
    11461 taacacaatc atttacttct tccattgtaa cgttatcttt taagagatag caattatttc
    11521 ttattatacc taaaggattt cttatctcat gtgctacccc agaagctaat tgtcctatag
    11581 atatcatttt gttttctcta agtaatttcg cctctactat tttatcatta gttatatctt
    11641 taataagaac tactatgtac tcagtattat tttttttata ctctacagga aaagtattta
    11701 tctttaaaat cttattgtgt acttctattt cactagtttt attagtgttt tcagagaagg
    11761 tattttcaat aacacctttt atcatgtcaa tcaaatctgc tattttataa ctcatttcac
    11821 ccataacatc atatagtact ttgttcgatt ctactatatt gttattttca tctacaagca
    11881 ttattatatc tgtgatacta ttaaaagttg cctctaaagt ttttttattt tccattactt
    11941 cttctgtttt tctttttatt tctatcttta acaaatatgt atagctataa aaaacataaa
    12001 ttgatattaa aattatacct ataaaaagat aaatactagg tacaattcct cgctcataca
    12061 atatatcatc aacttcatta tatgtagaat accatttttt ctttaaatct ttatacactc
    12121 catttttctg aagtttaaaa atgcctttat ttaaaatact gaccagctct tcatattgtt
    12181 taggtacagc aagaactgcc tttttagtat atataggatt acttagaaca ctgtatttat
    12241 ttgaaattcc ataattattt atataatatc gcaatactgg ttcatcacca acaactgcgt
    12301 ctacttttcc cgatattaaa tggttgactc cagtctttat atctggagtc aataaaatgt
    12361 ttatatcttg aactttttgc tttaaaaaat ttatagaata atcaccttct ggaattgcta
    12421 ctgtttttcc ctttaaatcc atgtaactat ttatatcttc agatttttta tcttttaata
    12481 tatttgcact caaagtgtat attgggtcag taaatataaa tttacttgcc ctttcctttg
    12541 atggaatcaa gtcaaaaaac tttatactat catctattga atttatgaaa gattctttcc
    12601 accaattatt gggtttaaaa taaaaatctc taccaatttg aattgacaga gaatttatta
    12661 aatcaacaac aattccctta tattgtccat cttctttacc cttatatctc aaaggaggtg
    12721 aactttggtc agaactataa atcaaattct tgtgtttttc taaccacttt ttttcttctt
    12781 ctgtaaacgg aagtgatttc ttaatatatt caaatacatt tagattatac tccatattta
    12841 catacatatt tgtaagtgaa aatatcacta aaaaggaata aataatccct ataataacaa
    12901 tccttttttt attcacttta aaactccaat cttctttttt actataataa attcaatatt
    12961 taataacaaa atcctacttt tttcattgaa tatttatatt tattataaaa ctaattgaat
    13021 agatgttgaa attatagtca ttactattcc tatcagtgct tcatatggaa ttaatttaaa
    13081 tctttcacct atatccatat ttatactacc tgcactagta tgaaatagtg agccatgtgg
    13141 taattgttca aatacactag acccagaatt tattattgat gcacctgaaa ttggtgataa
    13201 tccaccattt attatagcat catgaaaagt agatgatgct atagtagcac cagctgttga
    13261 tgatgctgtt gctaacgaca taagtatacc cgaaactggt gccaataaaa attgtggcat
    13321 atttaaaaat tgtagagcag ctattgtgct ctgttgtaat tcagacatct gtataattcc
    13381 tgcaatagtc cctgttccaa gtaataatat acagacccct tgcatcttag ataatccaaa
    13441 agctaaatat tctcttgaat tgttcaaatt tcctgtgaca attagagtta ctattcctcc
    13501 tattggaaga gctatcatgg ggtctataac tataggaaat acatttccta aaaacaatag
    13561 aaatatagct atgattggac cacataatga tttaaataaa cttggtaagt cctctctttt
    13621 ctctaagatt tcatatgatt gtactttatt ccctttattt attaatatac ttgctaaaat
    13681 aactgtaata ataactccaa caattgctgg aattatattt gcaatcataa cactagagag
    13741 attgacagaa aaattacctg atactgctat agtatttggg tttggtgata ttatattacc
    13801 tgctttacct cctcccaaca tggcaaatag tattgacaat ttagaataat ttaattttct
    13861 acctatatat aatcctatag gtgctacagt tattatagat acatccaaat ttactcctac
    13921 tccagcaagt accatagttg aaatggcaat cgaaagtaaa gccctctttt caccaaatat
    13981 ttttacaatc tgttctgata ttttatctac tgcccctgtt tttattaaac ttccagctaa
    14041 tacacctgat gccaaagctc taagaattga tggtgatata ttcatagctc cagttgccat
    14101 aaaatctaca gtttgtgtta tgtttgctcc tccaactaat cctccaataa atgctcctaa
    14161 cattaaacta tatacagctt gaaatttttt tataattaaa ataattgcta ttaataaacc
    14221 aaatatagct ccaaaagtcg ttatttgcat aatatcccct cctatcataa attaattatc
    14281 ttttatttaa atatatttta agtattctgt atccactttg tcaattatat tttaatttgt
    14341 ttaattagat tgaacatagt tttttcaaaa cctcattcta tatgttataa taatttcata
    14401 ctatataatc tttttacttg attattttaa gttaatattt tttaaattaa aaagagagga
    14461 tatttatatg aatgatttaa atttaggtga aaaaatagct gaagttcgaa aaaaacaaaa
    14521 cttaagtatt cgagatttag caaaactagc tgatgttaca ccatcattat taagccaaat
    14581 agaacgaggt cttgctaatc catctgtaaa ttcattaaaa tccatagcct cttctctaaa
    14641 cgttccttta tttacatttt ttgtatctga ggtagataaa aaaaacttga tagtaagaca
    14701 taataataga aaaaaagtta ttttacctgg aagcaaaaac gttgtatatg agattttaat
    14761 tccagattct agtggcaatt tagagtttgc aattatgaat ttagctccaa atacttcttc
    14821 ttgtgttgat agaattactc ataatggaga tgaaattgca tatgttttgg agggagaggt
    14881 taaacttttc atggatgatg atgaatttac tttattcaaa ggagatagtg taaaagttcc
    14941 tttaggaaca aagcataaat ggcaaaatga ctcaaatagt gaaagtaaag taatttttgc
    15001 agttatcttg taaaggagta aaaaccatga agacatataa atttatattt tttgatgcag
    15061 atgatacttt atttgatttt aggaaaagtg aatcacatgc ttttaaaaaa cttctatctg
    15121 agtttaattt agaacttaat tttgagaatt atataaaatc atatagaaat ataagtgata
    15181 agctttggct tgaccttgaa aaaaatatta taactttgaa tgaacttaaa ttacttagat
    15241 ttgaactttt tgcaaataaa ataaatttgg atgttgattc tgaaaccctt agcaaaatgt
    15301 acttaaattt tttaggtgaa tgtacatttt taattccagg tgcaatcgat atattgccat
    15361 atcttaaaga aaaatatact atagttataa taacaaatgg aatttatgag gttcaaaaga
    15421 aaagacttga aaattcaaga ataaaaggat atattgatgg aatagttgta tctgaagaat
    15481 taaaaatatc aaaaccaaat cctgaaatat ttaaatacgc tctcaaaaag tttaattgcc
    15541 atgataaatc ttctgcttta atggttggtg atagcttaac ctcagacatc ttaggtggaa
    15601 taaattcagg aatagatact tgttggttaa attccaacaa caatataaat tatactaatc
    15661 atataccaac ttatgaaata aatacacttc ttgaattaaa taaactacta tagcttgtaa
    15721 atctgttcag attaaacaga atattatttt gcaataattt ttttagttta tatacaaaat
    15781 aactaaaaaa attattgcaa ttcatacaca gaacaaatct cagtcttgaa aactatctaa
    15841 aaacattttc taggacactt actacatctt gattctaaat tttcttcatc ccccattaaa
    15901 ataagcattg caacactttt tatgggcgat agttgatgat agtcattgat ttctatttct
    15961 acactactat atttattttt tatatagtta taaatatcct tttgtctctc tacttcaaat
    16021 tctttatctc ctggatatat ttcatgcgat attttgagac tatcatactt ttcttttaaa
    16081 tacattttta ttttctcatt aatgcaatct aaacatacta tacctatttt atccaatgct
    16141 agtcctgcca tcatgttgca atttttcata tagtcgttca tcttgatgtc aattttatcc
    16201 cctattgtat acattacagc aaatgccttt ttacattctt taggtgtttt atcaatatta
    16261 acttcactta tatatatctt aatatctaaa atatcattta tatttcttat ttctctttca
    16321 acgatttcac taattgtatc aggagctttt ctatttccat atcctaaaaa ctttagtaca
    16381 atattcttat ctataaaaat atccgctaaa tttatatctg ctaaaataaa tttatcttta
    16441 ttactattat aattcattaa tatcaatcct atctaattct ttataactaa ttcttcctgc
    16501 ctttatagct gcttgtaaat tttctactgg agtggtattt aaacagttac atccaaaatc
    16561 acataaaaaa ttatcatatc ctctcatctt ctttaacaat tttagtgtct ctcttctaat
    16621 tttatctggt ttagaacgtc caagaagttt tattgggtct aaattaccaa tcaacactat
    16681 atctctagga atcattggag caatttcttc atagtctaaa atttggtcta aacttactgc
    16741 atctatattg caatctaaca tattatctaa taattctctg gtatctccac atatatgcat
    16801 acctttccaa caatcaagtt catcatagat tttatttaaa ttttttacta tatattcatc
    16861 aaatctatct ttacttagag ttactgatgt tggctctgct attgaaatat actttgctcc
    16921 tgctttattt gcagccacag catatctcct taccaattca gttgtaaatt ccaacaattc
    16981 ttctacaaat tttttatcag ttattataca tcttaaaagt tgagtagctc cagctaattg
    17041 acctgcaagt gtaaatggac cttgtatcga ttcatatagt ggctttttaa tactttttga
    17101 tatcagtgat aagctttcta tattgagtgg catacgtcca ctcgtataag ggtctggaac
    17161 atctaatttt cttaatttct ctctgtcagt tatagtatgt gtcaatacac ttggaaaatc
    17221 ataatctggt cttaatgttt ctaaacccag agtttcacaa aatgtaatcc catcacagaa
    17281 tgagtatata aaatctgatt caaaatattt gtccatagtc tttgctaatt ctaattgcaa
    17341 atctacacta tcatatacct catatgcctt tttatttatt aagaacaatc catttgttcc
    17401 catatcaggt agaaaaaaac ctctgtcttc actatttata tactgaagta aagtcatatc
    17461 tgaaaacatt taaacttcac ctcctataag tttatttatt aatttgactg cttttggagc
    17521 atttgaacta tatccatctg ctcctatttc ttctgcaaac tccatactta caggacctcc
    17581 accaattatt acttttggtc ttttatctac cttaatccta ttaagttcat ctataacaga
    17641 tttcatattc tccatagtag ttgtcatcat tgaagataag cctattatat ccacattgtt
    17701 ttttatagct tcttctatta tgtcttcact ttttctattt acacctaagt caataacttt
    17761 atatccagtg gcttctacca ttacttttac aatatttttt cctatctcat gagtatctcc
    17821 ttctactaca gacattagaa ttactccctt tgattttttc tttacttttc cagttttttt
    17881 caaaatatta atgcctttat ttaatgcatc tgtgcatact ataacttctg aaagatagta
    17941 ttctttattt tcaaatttat ctaaagctcc tatcatacct ttgtttaaac catattcata
    18001 aatatcttcc acatcaatat ttttatctat agcaattttt actaaattct ctatattatc
    18061 tacacccata tttaatatac attctgctat atcatcaagt atgtccatat aatactcatc
    18121 ctttctaatt acttacaaaa ttaccttttc aatatccaat aatttctttt atttaacaag
    18181 gactagctct aggtatcaat caattttatt taatatcatc taaaagtaca acaactattg
    18241 ataatttaaa tttgcagtcc atgggaaatc tacaggaaat gcctttgtag caaatttata
    18301 tatatttttt agatgtttaa attcattgta ctgttcttca tttttttcaa aaaacagttt
    18361 attaagctta tccaaacttt ctattacaag ttcttcttct ttatatttaa taatatattt
    18421 attttcaact tgtttaaatt ccatgtattt taacaattca gaatctacat attgactaaa
    18481 ataacttctt aagctatcac acaacttagt aaaatttatt attttcatag ttccttgttg
    18541 atagtccaaa gattttatcc cattacattt caactggtct ttaagatttt tcacatgtac
    18601 tttataattt aaatattcta atccgaattt atttgcaaca tatttcaata tattttcaac
    18661 atttacagag tttaacccta tttcagcaac ttctcctaca gtagagtctt ctttttttat
    18721 tgttcttatt atcaaatatc ctattatatt attattttcc tttataaata ccttattgta
    18781 agcaatcgtt ccccaggcaa tagttgctgc atgcaatagt ttttgaaact catctctcgt
    18841 tcttataaat ctagtactat tttgattata tagttcaatc attttatcta aatcatcatc
    18901 tttttcaaaa ttagtttcat caaattcaac tatttcatat ggtattttta catcttcagg
    18961 ttttattgta tatttataga aactctttac caaactgcaa tttcttctac tgtatagact
    19021 tcttgttcct gatataatta caatatctac accatcataa aacatttttt cttctacctt
    19081 atccaatatc ttagatgaat agcctctctt ttcataatct ggatgagtac atactccacc
    19141 tatagctgca accttcaatc tatttccttg aatagataca tcttgaatta gatagtttac
    19201 atcagaaacc actttatcat cttctgatat tataatcata ttttctatat tatttttact
    19261 tagtaaaaga ggaaattctt ccatcatagt tggtttatga tttcttgata tcctaaatac
    19321 atagtttatt aattctatta ctttatcaaa ttcttctaat tttgcacttc ttggtcttaa
    19381 ttccattcat attcctccaa atattattta atatacttaa aactttatta tctataataa
    19441 aacatttatt actacagttc taattatatc ttttttcttt acaattttta attgtttttt
    19501 tcagcaaatt tttataaaat ataaacctaa tttctagtta aacttataaa
//
LOCUS       DAMKOJ010000064        19507 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000064 DAMKOJ010000000
VERSION     DAMKOJ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.069"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..955
                     /locus_tag="PC592_002603"
     CDS             <1..955
                     /locus_tag="PC592_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4056555.1"
                     /translation="KEINYFLLINFLLIAFTSIFLFLSISKPNNSELISSFSILFMYI
                     PAFSAIVVLKKVSNYKFDSTVDKFLKFFAITTIVRIVISIAETFLIYSSIISSTIDTL
                     TSVYLLAVVLYNEFQFEVLNLSLSKNFKKVLGILLIFLILIIVRNIIDKEGLSINVVN
                     KFVTVFINIIINLCFGFNLFFGEEFGWRYFLQPRLQKIYGKKFGVLILGFIWGIWHLP
                     LCVTLYSPETPFYCVISQISYCTFIGIFLGYTYMKTKNLWAPILIHLVNNTVSIILGG
                     SIESIFTLESLLWSILVNAILFLPFLFAKEYKANNYDESSN"
     gene            complement(1171..2046)
                     /locus_tag="PC592_002604"
     CDS             complement(1171..2046)
                     /locus_tag="PC592_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDF4056556.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLD
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTVKKMSNYLYNDCFKIHYAVVDALIENRITE
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(2228..2914)
                     /locus_tag="PC592_002605"
     CDS             complement(2228..2914)
                     /locus_tag="PC592_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDF4056557.1"
                     /translation="MFGVIANSLAIAGGCIVGLVIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(2963..3502)
                     /locus_tag="PC592_002606"
     CDS             complement(2963..3502)
                     /locus_tag="PC592_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF4056558.1"
                     /translation="MSDLNNKIIKERDENEASMNETKIYDILNKLNVEYDVVEHEAVY
                     TAEQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFA
                     SPERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVLKEDYLNFHPNINTKTVNISR
                     KGFEEFLEYLKYPIQSIDV"
     gene            complement(3548..4180)
                     /locus_tag="PC592_002607"
     CDS             complement(3548..4180)
                     /locus_tag="PC592_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDF4056559.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNKNIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(4267..5349)
                     /locus_tag="PC592_002608"
     CDS             complement(4267..5349)
                     /locus_tag="PC592_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF4056560.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLKNDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLKFIKNIY"
     gene            complement(5482..6828)
                     /locus_tag="PC592_002609"
     CDS             complement(5482..6828)
                     /locus_tag="PC592_002609"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF4056561.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGNGEKMIGILGHVDVVPEGDLESWNYPPF
                     EGIVEDGKLYGRGTQDDKGPTISAIYAVKVLMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDSEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTILVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKAAQIYALSIYELLKI"
     gene            complement(6897..8177)
                     /locus_tag="PC592_002610"
     CDS             complement(6897..8177)
                     /locus_tag="PC592_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HDF4056562.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEDIKGKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(8304..8561)
                     /gene="hfq"
                     /locus_tag="PC592_002611"
     CDS             complement(8304..8561)
                     /gene="hfq"
                     /locus_tag="PC592_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDF4056563.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNR"
     gene            complement(8675..9610)
                     /gene="miaA"
                     /locus_tag="PC592_002612"
     CDS             complement(8675..9610)
                     /gene="miaA"
                     /locus_tag="PC592_002612"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDF4056564.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEAEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIYEINEKGKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQNQLAEKGIDYMHNRLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSNDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLEQYENIDELKNEIILYIKDSIK"
     gene            complement(9631..11595)
                     /gene="mutL"
                     /locus_tag="PC592_002613"
     CDS             complement(9631..11595)
                     /gene="mutL"
                     /locus_tag="PC592_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDF4056565.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGMGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIRDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNDNLLESTPKNSNTTKSKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASEDEVNNINYLSEDSANDNIQEEFQVDGIRNEGNYYLGDSIKD
                     SEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKNDSMYLLDQHAAHERILYERYMEKF
                     YRQDINMQILLDPVIIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIFG
                     VPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLEK
                     CENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(11606..14449)
                     /gene="mutS"
                     /locus_tag="PC592_002614"
     CDS             complement(11606..14449)
                     /gene="mutS"
                     /locus_tag="PC592_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDF4056566.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSGMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAEYADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKVLNDEVALMKQNDDKEKTNQDDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(14612..15346)
                     /locus_tag="PC592_002615"
     CDS             complement(14612..15346)
                     /locus_tag="PC592_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056567.1"
                     /translation="MLTQMNFYQNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLVL
                     KKEKRNKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRNLNEDNLENIIKLKKEIISLL"
     gene            complement(15315..16328)
                     /locus_tag="PC592_002616"
     CDS             complement(15315..16328)
                     /locus_tag="PC592_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4056568.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKNASSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVAAVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEEASKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPK"
     gene            complement(16350..17120)
                     /locus_tag="PC592_002617"
     CDS             complement(16350..17120)
                     /locus_tag="PC592_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056569.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSVVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHSVVTIGEAVLGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MNSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQFVKKIVIRHRLTD"
     gene            complement(17095..17385)
                     /locus_tag="PC592_002618"
     CDS             complement(17095..17385)
                     /locus_tag="PC592_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDF4056570.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(17517..17616)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(17741..17875)
                     /locus_tag="PC592_002619"
     CDS             complement(17741..17875)
                     /locus_tag="PC592_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF4056571.1"
                     /translation="MNKNKNLAQCLDGIDIYPNMLEIVKQKLENYVNLVLGDTEKLSF
                     "
     gene            complement(17890..18063)
                     /locus_tag="PC592_002620"
     CDS             complement(17890..18063)
                     /locus_tag="PC592_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056572.1"
                     /translation="MIFLYYSGCEPQEEPCVVEINQESDYEITYLEYNFKEFIEGIFV
                     YKDECSIKTMLNQ"
     regulatory      18585..18674
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            18727..18903
                     /locus_tag="PC592_002621"
     CDS             18727..18903
                     /locus_tag="PC592_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056573.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(19018..19374)
                     /locus_tag="PC592_002622"
     CDS             complement(19018..19374)
                     /locus_tag="PC592_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4056574.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLESDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
BASE COUNT         6185 a         3308 c         2063 g         7951 t
ORIGIN      
        1 aaaagaaata aactatttct tattaataaa ttttttactg attgctttta catcaatatt
       61 tttatttttg tcaatatcaa aaccaaataa tagtgaactt atatcaagct tctctatatt
      121 atttatgtat attcctgcat tttcagcaat tgttgttcta aaaaaagttt ctaattacaa
      181 gtttgattca acagtggata aatttttaaa gttttttgct ataactacaa ttgtgagaat
      241 agtaatatct atagctgaaa catttttaat ctatagtagt attatttctt caacaataga
      301 tacattaaca tctgtttatc ttttagcagt tgttctttac aatgaatttc aatttgaagt
      361 tttaaattta tctttaagta aaaatttcaa aaaagtttta ggcattctat taatattctt
      421 gatattaatt atagttagaa atattattga taaagaaggt ttatcaatta atgttgtaaa
      481 taaatttgtc acagtattta taaatataat tataaattta tgttttggtt ttaatttatt
      541 ttttggagaa gaatttggat ggagatactt tcttcaacct agactacaaa agatttatgg
      601 caaaaaattt ggtgtattaa ttttaggttt tatatgggga atttggcatt tgcctctttg
      661 tgtcactttg tacagtcccg aaaccccatt ttattgtgtt atttctcaga tatcatattg
      721 tacctttata ggaatatttt taggctatac ctatatgaag accaaaaacc tttgggcgcc
      781 aatattaatc cacttagtaa ataacactgt ttctattata cttggaggaa gtattgagtc
      841 tatatttaca ttagaatcac tattatggag tattctagtt aatgctatat tatttttacc
      901 attcttattt gctaaagagt acaaagctaa taattatgat gaaagttcta actagtctac
      961 aaatacatga ttctttagac atagaagctt tttatatttc ataacaaaac cctcctagtt
     1021 ttagacagtt ttacacattt taactgtctc ctaagagggg tctagttcat tttgagaatg
     1081 gtttttaata taaacgattt attattaata aggatatttt tttatttaaa tttatataat
     1141 cgaacatcta atatttaatg tttaataaaa ttatgcattt gcaaaagtat atatggcatt
     1201 aacccttgct acatataaat tctcatcact acatccaata tatctagcat atttttcaat
     1261 cttttccttt gcattttcaa catcattttc gtcgctctcc attaactcat ttatataaat
     1321 atccattaat gatgctttat attctcttat atcataacct aaaaattcag tcaatctctc
     1381 aatttcctta ctaaaatctc catcttcttt taccaaaaat tcgtatacat cttccctata
     1441 tggatttaaa gttattattt gttttactac tttacattcg tcagccttcc caataaaacc
     1501 atctttataa ttattaaata aggcattaga tttttttata gattcttcat caatataaga
     1561 atgtacctca gttatacgat tttctataag agcatctaca acagcataat gaattttaaa
     1621 acaatcattg tataaataat tactcatttt ctttactgtc gattctattt ctaaaaaact
     1681 agcatgaccg ttttttttat ttttatttgg tataataaag gttttattta aattattaaa
     1741 aagtctctta aaatctaaat atttttcaca ataaacactt ttaaaggtat cgatatctat
     1801 agttataatt ccaaaactca ctatagtctc aatgcctttc ttaaaagact cttctatata
     1861 tttttctcct agacttaaac ctctatcaga tatttgcttt agattttgga aactatctaa
     1921 gcaatctctc tcaaagtttt tagatatttc taaagcatat aatttaaata ttttccttat
     1981 cttattataa ttattttttg tatcatcaaa cctgataata gctccattta catcaaaagt
     2041 aatcattgag ttttaacctc cccattagtt tcatcaataa aataaattta atataaactt
     2101 tataatcata atattaaact tatttatact ataattatta atttgatgat aaaagctatt
     2161 ttccttctaa ataaaaaatt tgtctaaagt ttctaaaaaa tttagacaaa tcttaggtta
     2221 ttacttttta aattattcca aatactccaa ataatattgg tataaatata gctggtaaca
     2281 aattggctac ttttatattc gtcaatttaa gtacatttag accaagacct ataattaata
     2341 aacttccagc tgctgtcatt tctgtaacta caggatcact taaaaatcca tttaaaaatg
     2401 atgctcccac acatataata ccttcgtaca aaaatacaga tattgcagaa aacattacac
     2461 ctatacctaa agaagcagta aatataattg aagctattcc atctataaca gattttacaa
     2521 ataaagtatc atgacttcct gtaagaccac tttctaatga gccaactact gccatagctc
     2581 ctatacagaa taataaacta gatgatataa aaccctctgc tatagaatct tttttatttc
     2641 ctttagaaaa tttactttgt aaaaaagcac ccaacttatt tacccattta tcaatatcta
     2701 ttaattctcc tatcaaagca cctacagcta cggatattat tgtcactaat gtgttttttc
     2761 cttctagtgc tcctgatata ccaatgtaca atacacatag ggcaattcca ttcattatag
     2821 tatcgctcac tctttgaggt aatcctcctt ttattacaag acctactata catccacctg
     2881 caattgctag actatttgct attactccaa acattttttc tcccctcgat tagctaattg
     2941 aaatttatcc tactattaaa acttaaacat caatactttg tattggatat tttaaatatt
     3001 ccaaaaattc ttcaaagcct tttctagata tattcacagt tttagtattt atattaggat
     3061 gaaaatttaa gtaatcttct ttaagtacat ctttatctat gtaaagctca acttttcttt
     3121 ctgtatcatt tattaatgaa aaaggattta cacttccagg aagaagttta agtacattgt
     3181 atagtctttc aggtgaagca aatgataatc tagagctccc tatcttatct ttaagtgaat
     3241 ttaaatcgac ttgtttttct cctttaacta caataagata atacttattt cccttagcat
     3301 ttcttaaaaa taaattttta cattggcatc cctttgttat tccatctaaa attactaatt
     3361 gctctgctgt atatacagct tcatgttcta ctacatcata ttcaacattt aatttattca
     3421 aaatatcata tattttagtt tcattcatgc tcgcttcgtt ttcatctcgt tctttaataa
     3481 tcttgttatt taaatcactc atactttctt ctccttaaac cctccatcat catatcattg
     3541 tgagatatta ttctactata gctattgctc ttactggagc tccgtcagca tcattatact
     3601 taaatggcgc tgctataaat agaaattttt ctggaacatt ttctaaattt gtaagatttt
     3661 ctatgattat ttttcctttc tcaaataaaa tatgatgcac ttcaaatact gatgtgtcat
     3721 atctatccac tgataacatg tctattccta tcccttttat attagtatta gctatataat
     3781 ttgcagcttc ttttgttaat gtaggatagc ctacatagta ctgcttttta tcccaaaact
     3841 ttgaccaacc tgatttaaat attataaaat cactattttt tatttcatct tcatattttt
     3901 ttagatattc taactctata ttcttatttc ccttttcaag ctccaataca taagctttcc
     3961 caacaaaatt ctctatatcc aacttatcta gggtctcacc tttagtgtac atatgtcttg
     4021 gtgaatccat atgagttccg ttgtgagaaa atacactaat taatgtttct tgataaccat
     4081 tttcttcaat aatagctact ttcttgatat ctggtctatt aggctctgca tatacaggca
     4141 tgtcattatg tgtcacgtga gttaaatcaa aaaccttcat ctttatatac cccctatgtt
     4201 tttattttct attatatacc taaattcatt ttatttctat cagattttat tccattatat
     4261 accatactag tatatatttt ttataaactt caaaggattt accgaaaaat cttggaaaga
     4321 attatcagta aatataacat cttcacccaa aaaacgttta taccttccct cttctttctt
     4381 taaagtaatt ctctgttttt gtgaatggtt attaaaaacc attatcttaa gtggaggttt
     4441 ttttctatta gtctgaactc tttttaacat gtattttatg tgcatgtcag cttcgggaaa
     4501 tgaatatcca caaaatatta aaaggtcagt atctcttaaa gttttttctg tctcattcca
     4561 aacattactt aagaatatat tggacatatt cttaaaatac gttggtggca ctataatagg
     4621 ttctgtcaat tcaccacact ctaaacattt tgtttcagaa ctattttcaa taagtttcat
     4681 aacaccacct tcatgtggtg taagagttac actattacaa ataggacaat aaagccaatt
     4741 caatgaccca tgtatcttat ataatttgat taatggctct ttcggttttc tccaatttaa
     4801 ttcttcttta aaatttgtaa actccacacc ataatcaagc ataattggca aatcattctt
     4861 atctcttaag ccagtaactg tattatctat atgtatatca taatttgcac tgataaaagt
     4921 agtatctaaa agcaaatcat ttttcaaaag attttcaact aaaagtttat gatatttatt
     4981 atctgttcta ggtgtattat gaattgcctc agccattagc agtattaaat attgtcttaa
     5041 aaaacgtata ctatcacttc tgttattaag attttctagt ccaaaatttc taaatgcttc
     5101 ttttctttgc tctgctaagt ctaaaagccc taaaacttct tcaaaggtag gaaaatttgc
     5161 attatctata ttatctttta ctatatcaat gttaaacatc tgtttaaaga aaatatacaa
     5221 ttctctattc attttggtat tataattggt aggatttagt tttttaaaat attcactaaa
     5281 cagttcattt tgaataggta gattctctgc tgctgaagct cctgctccta aaaatattgc
     5341 tattttcata tagttcctcc taatataaat attactccta tttttatatc cgttaaatat
     5401 ccatatcatt tgttttatga tacaataata aagctgtccc ttactagaaa aaatcctatt
     5461 acaagacagc cttatattat attaaatctt taataattca taaatagaaa gagcatatat
     5521 ctgagcagcc tttataatat cctctactat taagtattca ttagcttggt gttctgtttc
     5581 tggttttcct ggaaaaatag ctccaaatgc aacacaattg tctaaagctc ttgcataagt
     5641 tgctcctcca gatgaaagtg gtgttccatc aagaccagtt tcttcttcat atacttttct
     5701 aagtgtctta acaagaattg tatcttctgg aacatagatt gaatccaaga aatcatattc
     5761 ttcataattt aaattgtatt tatccgtcat tttctttaat tcttttacaa aatcatcttt
     5821 cttgtatgtt actggaatcc ttacatctat tcctgcaaat tctttttcgc tatcaatagt
     5881 tactctacct atatttactg ttagtttacc tgacacatca tccttgcaat taggaattat
     5941 attgtttcca ttagcatctt caccaataac ttctgctaaa aatttaatta tattagaatc
     6001 tatacctata ttattaagag ctatacaaag tctggccact gcatttatac cagtatcact
     6061 cgctgctgaa tggacacttt tccctattat acagatttta ttaccttcaa cagtatactc
     6121 aaaatttaat ttatcaagtt ctttttttaa tttatcagag tattttccaa tatagattgc
     6181 tttacctgga actgcattta gagcctttcc aactgataat tctatatcgc ttttgctatc
     6241 acaagtcaaa tgaacttgta aaagaccttt ttctgcattt gttattggga atctagaatc
     6301 tggagtaaat ccatagtttg gtatttcttc attattttct ttatatttat ttatacatct
     6361 ccaaagattt tcttcgtcag ccccaaaaat gaatcttatt ctcttattaa aatctacatt
     6421 taaatccata agaactttaa ctgcataaat tgctgatatt gtaggtcctt tatcatcttg
     6481 tgttcctctt ccatacaatt taccatcttc tacaatacct tcaaatggag gataattcca
     6541 actctctaaa tcaccttctg gaaccacatc aacatgacca agtataccta tcattttttc
     6601 accgtttcct atttctgcat atccataata tccatctttg tatactgtct taaaacctag
     6661 agatttacat aagtctaata tacctcttaa agctttatct acattttcac caaatggaca
     6721 attttcagtt gcttcagata taacactagg tatttttacg ctttcttgta ttgaagaaat
     6781 catttcatct tgtagagaat ttactttttc tttaatttgc tctttcatat tatcaccctt
     6841 caattttcat cataatatac taataaatat tttgaccttt ttaaaaaaaa atatgcttat
     6901 tttttcagtt tttttataaa ttcaattgct tttaaagtcc ccatttttga atggtcaaat
     6961 gtaagtcctc cttggaaata aacattataa ggaggtctta ttggagcatc ggcacttaat
     7021 tctatagaag aaccttgtat aaatgctcct gctgccatta ttacttcact ttcgtatcca
     7081 ggcatgtccc aaggaacagg tttcacataa gaatcaactg gtgcagcttc ttgtatacct
     7141 tcacaaaaac ttattacttc atcagcatta ttaagtctaa tacattgaat aatatcactt
     7201 cttaagtcat cgtattttgg taatacatca taacctaatt tttcaaaagc tcttgaacaa
     7261 aagatagctc ccattacagc ctgagatact atgtaaggtg ctaagaagaa accttgaagt
     7321 acatttctag tagttccaaa agtaaggcca cactcttttc ctattccagg agaagtcatt
     7381 ctataagata taagctcaat taaatctttt ctaccagcta tatatccacc tgtcaatgca
     7441 agaccaccac caggattttt tattaaagaa ccagccataa catctgctcc aacatcagta
     7501 ggctctttgg tatctaaaaa ctcaccataa caattatcaa ccattactat agcttctggt
     7561 ttaacggact ttattacctc tatagcttct tttatatcac taattgaaag cgattttctc
     7621 caagaatacc cttttgacct ttgtatcata acaagtttag ttctatcatt tattttgttt
     7681 ttaattcctt ctaaatctaa gtttccatct tctaaaaaat ctacatcatc atatgtaaca
     7741 ccatactctt tcaatgaacc tttttcttct cttataccta taactccctc taaagtatca
     7801 tatggtctac cagtaacaga taaaatttca tctcctggtc taactatacc ttgtatacat
     7861 aaagtaagtg catgtgtacc atttacaatt attggtctta caagagcatc ttctgtatta
     7921 aatactttag aataaatttc ctctattttt tcacgaccaa tatcattata tccatatcct
     7981 gtagtccagt taaagtgcat atcacttagt ttagattctt gcatagcttt taaaacttta
     8041 tattgattgt attctcttat ttcttttatt tcttcaaact ttccttttat atcttccatt
     8101 atttcttgag atagtttaaa agtatcatca tctatcccat agtagtcttt caataattct
     8161 tttgtctcat taagcatttt atcacctgtc tctttattgt tttatttaaa tatgtaaagg
     8221 agactatttt actaaaacaa ataaattata gtttatcagt tagtataagt ctcctctcaa
     8281 ttatcttaaa ttaaattagt tatctatctg ttgttattat tattattttg attttgattt
     8341 gttagattaa tatactttcc aggttgtata gttgatacag catgtttata aatcatgttt
     8401 tgttgtctat tatccccttc tattaatatt atataactat caaacccctt tacaagccct
     8461 ttaacttgca ctccattgac taagtatata gtaacgggta tcctttcttt ccttgcatta
     8521 tttaaaaaca aatcttgtaa atttaaaact gtatttttca ttagatttgt accctcccaa
     8581 gattaaattg aacttctaaa atattcctac cttatattct atataagtta tgacaaattt
     8641 tcaatattaa gttgtatact taaaaattta tatattattt tatagaatct ttaatatata
     8701 agattatttc attttttaat tcgtctatat tttcatattg ctctaaatca aaccactttg
     8761 ctgttttata tcttttaaac catgttatct gacgttttgc ataccttcta gaatctcttt
     8821 taattatttc aatagcttct tcatatgtat attctccatc cagatacttt aatatctcct
     8881 tatagcctat accttgcatt gatatcatat cttttttaaa tcccatactt aaaagttttt
     8941 ttacctcttc aaccaatcca tttttaagca taatatcaac tctcatattt attctttgat
     9001 ataaatgttc tctatctcta tttagaacta ttattatcgg ttgatattct tcattaaatt
     9061 ttaaatcatt ggaaaaatca ttcattttct tgccacttag gcaaacttca agagctctta
     9121 tgaccctttt agtattgttt ttatggattc tattagcaga ttcttcatca agttctttta
     9181 gcctattatg catgtaatct attccctttt cagcaagttg attttgaagt tcttctctta
     9241 attcattatt agcatcagac tgtgcaaaat ccatattata tattaaagag tttaaataaa
     9301 gtcctgtgcc tccagttact aaaacacatt ttcccttttc atttatttca tatatatatt
     9361 tttttgctct ttgttgaaac tctgaaactg aaaatggata gtccggttta acttcatcta
     9421 taaggtaatg ctttactcct tgcatctctg cctctgtaac ttttgcactt ccaatatcca
     9481 tatattcata tatttgcata gaatcagctg aaattatctc tgcattcata tcttttgcta
     9541 attttattga caaatctgtt tttccaacag cagttggacc tgtaagtatt ataagtggta
     9601 tttttttcat agcattcctt tccatatatt ttacataatt cttttaaaca ttttctctat
     9661 ttctgtctta gatatttcaa ccattatagg tcttccatga ggacatgtaa atggattctc
     9721 acacttttct agctgttcca ataaactttt tatttcaata tcatatattt tgtcatttgc
     9781 ttttatagca gacctacatg ccatagatgc aaacctctct ccttttaaat cataattact
     9841 tgtaatttct tctatattat caattatttg aagtataaat ttctcagttt caggcactcc
     9901 aaatatagta ggaacacatc ttaccattat atgattattt ccaaatatct ctaattcaaa
     9961 accaaatttc ataaataact ccaaattatt ttcaatttga agcatatcta catttgatac
    10021 ttcaataatc actgggtcta aaagtatttg catattaata tcttgtctat agaacttctc
    10081 catatacctt tcatacagta ttctttcatg tgcagcatgt tggtccaaca aatacataga
    10141 atcgtttttg ctcaaaatta tataggtatt aaatacaact ccaattacag aatatccata
    10201 taaggaaaac ttgcgttttg agctacacaa gtactcttct tcactatcct taatactatc
    10261 tcctaagtaa taatttcctt catttctaat tccatcaact tgaaattctt cttgtatatt
    10321 gtcatttgca ctgtcttcac ttaggtaatt aatgttattt acttcatctt cacttgcatt
    10381 taagacttca cttactgatt gaaattcatt tattggtttt tcactcgata aagttacaac
    10441 ttcaataact tcatccttac ttttagtggt attactattt ttaggagtag attctaataa
    10501 attatcattt cttaatttat aatctgtact tttttctcta ctgttaatag cgattctagg
    10561 ctgtgttttt ttatcactat aagtagcata ttttccaata agatttgagt gtattaactt
    10621 aacctttaaa aaatctctaa gttctatata cacttcttgt tctttttcaa atttaatttc
    10681 aagtttattg ggatgtatat ttacatctat acaagatgga tctacttcta tatttaagaa
    10741 acaaactgca tgttttccta ttggaataat agatttataa ctttctgtta ttgcatctat
    10801 tattatttta ctttttacaa accttttatt tatatagata tgttgtaggt ttttattaga
    10861 acggtatata ttattattac ctatgtatcc attcatttta aagtgattgc acttaaattc
    10921 tacatctatt atattctctg ttatttcttt tccatatata cttctaatcg tatttacaag
    10981 cttcccatct cctggagtat ttagcatctg cttattgtta tttgtatatt taaattgaat
    11041 gtttggatta cctattgcaa gtttatttat caaatcactt atgtttatag tttctgcatg
    11101 agtagatttt aaaaattttt gtcttgctgg tgtattaaag aaaatatctc ttataatgat
    11161 tgtagtccca ttagtagagc ctatgggttc ttttgatatt atttttccac cttcaacata
    11221 tattttagtt cctattattt catctttagt tttggttgtc atttctaatt ttgatacagc
    11281 tgaaatagat gccaatgctt cccctctaaa accaagagag tataaatcat acaaatcatc
    11341 aattttttta attttactag tagcatgtct taaaaacgat ttttcaactt cacttgaagg
    11401 tattcccatt ccattatctg taatcttaat tagacttttt cctccatcaa ttatatctat
    11461 agaaatttta tttgcacctg catcaatgga gttttcaata agttctttta ctacagaaga
    11521 aggtctttct acaacttcac ctgctgctat cttatttata gtcaaatcat ctaggatgtt
    11581 aattatattt ttcattttta cacctctaag attttatttc ttttgctttt ctttgaagat
    11641 tataaagaga gtttatagca tctaatggag tcatatttaa aatatccaga tttaaaattt
    11701 cttctgatag tatgtctcta tttacactat caaaagatat ttgagttaag gctacttcct
    11761 ttacagaatc atcttggtta gttttctctt tatcatcatt ttgcttcatt aaagcaactt
    11821 catcatttaa tactttaaat ttagaattta atttatcata atcctttttt atatgcttgt
    11881 agtcttttac gataagttca tgttctattt ttagagattc atatttattc ttaaaattac
    11941 tttgatttac cttaactaat tcttcgtcta aattactatt aattatatta ttattttctt
    12001 tatctccatt tattgcaaca ctgttgtaaa catgattttt ttccaagtct ttaagtatat
    12061 attttgctct ttctataact tcgtctggta atttagccaa tttagcaaca tatattccat
    12121 aactcttatc tgctccctga ggaattattt ttcttaaaaa tattattcct tccccatctt
    12181 ctttgactgc tattgaataa tttttgacct ctttaaactc ttcttctaaa tcagtaagtt
    12241 catgatagtg tgttgcaaat aatgtcttgc atctaatgtt tttttgaata tattctacta
    12301 ttgaccatgc taaacttatc ccatcatagg tactagtccc acgacctatt tcatctaata
    12361 taactaaact tctctctgtt gcatttttta atataaggga tacttcgttc atctctacca
    12421 taaatgtaga ttgaccttga gataaatcgt cactagctcc aactcttgta aatattctat
    12481 ctagtattgg aatatcagca tactctgctg gtacaaatga gcctatatgt gccataagag
    12541 ctattatagc agtttgtctc atatatgttg atttacccga catattagga ccagttatta
    12601 tgttaataat gttttctcca cgatttaaat aagtatcatt tggaacgaaa ttttcctcac
    12661 ctactatatt ttcgacaaca ggatgtctac catttcttat atcaagttta ttattttcat
    12721 ttatcgctgg tttaacatag ttatttatat gtgcaaccgt tgcaagagag acaaagacat
    12781 ctatattagc tatagtctta gctacttttt gtattctatc tatgttttta tatattgtat
    12841 ctcttatctc tacaaatatc tcatattcta aagatttaat cttttcctct gcatgtagta
    12901 tcttttcttc tatttccttt aattctggag ttatatatct ttctgcatta ctaagtgttt
    12961 gttttcttat atatgtctca tctagctttg cctgtttaaa gttagctttt gttatttcta
    13021 tataataccc aaaaacttta ttaaacccta tttttaatga tttaactcct gttttttctc
    13081 tttctctgtt ttctatctcc tttacaagaa aggctccatt cttagaaatc tctcttaatt
    13141 ccttaagttc atcactaaaa tctgatttaa ttatgtttcc atcttttatg gttattgtag
    13201 gttcttctaa aatagcttca tctattaaat tgtatatatc atctaattta tccattcctg
    13261 aaacatactc ttttaggatt tttgcatttg atagatttat agtatctttt aaattaggta
    13321 acttttctat cgaatttttt aagtgaatta actcttttgg tgttactctc tcaaatgcta
    13381 tctttccaca tattctttct atatcgtata tatttttaag tatatcattt aggtcttctc
    13441 ttaatataaa gtcatctttt atttcttcta ttacatccaa tctattttca attttagatt
    13501 tgtttatcaa aggttcttct acatattttc ttaaaagtct acctcccatt gctgtagaag
    13561 ttttatcaag tacatgtaat aatgaacctt ttttcttatt ccctcttata gtttgggtaa
    13621 gttctaaatt agtcctagta aacatatcta aaaccatata ttctgatgaa ttgtatatat
    13681 ttatattatt aatgttagat gttatttgtt tttgagtatt gtatatataa ttcagaagaa
    13741 ttgataagct tgactttatt agacctttgt catcaaactt tagtttttgt agataaacat
    13801 ctggaaaata ttcttttaat atatttatgt ccaaatagtt atcgctaaaa ctttcattta
    13861 tgtatatatt acttacagta gctatatctc taagcttttc tataaagtct aaatcattta
    13921 taattatttc agttggatgg atttttgcaa tttcctcaat taccttatct tcatttaaac
    13981 atgttgcatt agtttctcct gtacttatat caacataagt tagacctata ttagtaccat
    14041 ccttatacaa agataacaaa taattattct ttttattttc aagtaaattt ccatctaaaa
    14101 ctgttccagg agtgatgact cttataacct ctcttctaac aattcctttt gctgtagatg
    14161 ggtcttccat ttgttcacct attgctactt tatatccatt ttcaactaat tttgatatat
    14221 atgaattggc tgagtggaaa ggaacaccac acataggagc acgttcttct aaaccacaag
    14281 cttttcctgt caatgctatt tcaagagctt ttgaagctac taatgcatct tcaaaaaaca
    14341 tttcataaaa atctcccagt ctaaaaaaca gtatacagtc tttatatcta ttttttactt
    14401 caagatactg tttcatcata ggagtcaatt tattcatatc tatttgcatt atcaaacctc
    14461 cttcttttct aattaaatat tatatcatag tagatgatta ttattaacac aatatataaa
    14521 attttgacgt ataactaaaa acaatccaaa atgtatactc acattttgga ttgctaagtt
    14581 taatacttat taaataaaaa tatatataat tttacaataa agatattatt tcttttttaa
    14641 gtttaatgat gttttcaagg ttatcttcat ttaaatttct actatctata acaaattctt
    14701 tctttactat tgatggtttt tttgaaataa cataaattct gtttgatagc attatagctt
    14761 cgtcaatatc atgagttata agaagtattg ttgaatttac ttttttctta acatctaaaa
    14821 gccatttttg catagatgtt ttagttaatg aatcaagtgc gccaaaaggc tcgtctaaaa
    14881 gcattatgtc attagaattt ataaaagttc tcaagaaatt agctctctgt ctcattcctc
    14941 cagaaagttc tgaagggtat ttatcttcat atccacttaa tccaaatacc tcaaaataag
    15001 gttttaccat tgacctagct ttattccttt tttctttttt taaaactagt ggtagtgata
    15061 cattatctat tatagtttta tatggcaaga gtaaatcttt ttgatacata tagctatatt
    15121 taccatttat attcactttg ccactatcat aatctgtaag tttagttata atattaaaaa
    15181 tagtactttt tccacatcca cttggcccta atatagaaac aaattcacct tcataaacat
    15241 caatacttat atcttttaaa acttcaatat ctttataagt ttttgataca ttttctatag
    15301 atacttttac ttttttattt tggtaaaaat tcatttgtgt aagcatcact tgccttcata
    15361 tccttatcta ttaatttata ttcttttaag aatgatgtat agttgttcca tacactatct
    15421 ttcatttctc cccatcgtgg tgcatcatct ttgtatttgc ttgctaaata ttcttgactc
    15481 tttaaggcta gtttttcatc tacttcaggt gcatgtttta ctaaaatttt tgatgcttct
    15541 tctggatttt ttattgcata ttcataacct tttgttgtag cttttaagaa ttttttagca
    15601 agctctggat tatctttaag cacagtttca ttcgaaatta taagtggtgt ataataatcc
    15661 aatctctcat ccaaatcttt tactggtata aaatttaagt cgtatccaat taaatcagct
    15721 ttaactgcat cccaaccttc aaatatccat gcaaaatcta cagttttcat agctgcaaag
    15781 aaatcatctt gaccagtatt gactattttt aacttattaa aatcagctcc atttttcttc
    15841 ataactgctt taaaaacagc ttcttctgat ggagaacccc aaccaccata agtttttcct
    15901 tcaaaatctt tagctgttgt tatattcttt tcttttggtg atgcaaatcc agaagtatta
    15961 tgctgtataa cagctgctac agcttttatt ggaagtgggt cttcactagt ctttgcataa
    16021 gtaacctgct cttgataact tataccaaag tcagcttttc ctgttgctac taaagtctcg
    16081 gctccacttt caggtggttg tactatttca acatctaaac cttcttcttt ataataacct
    16141 ttatcaagtg ctacaaataa tccagtatga tttgtatttg gtgtccaatc aagtaccata
    16201 gttacttttt tggaagaagc atttttatca ttgtttttat ctttattatt atttgaagag
    16261 catccagtta ttgttgccaa tgtaaaaaca cttactaaac ctaatattcc taatttttta
    16321 aaattcataa ttgcctccct caaatacctt taatctgtta atctatgtct tataacaatt
    16381 ttttttacaa actgtacaat tcctacaaac attaaactaa atataactac taatatagta
    16441 gatgcaaata ctttatcaag tgcatatgca ctttttgacc taagcatata aacaccaagt
    16501 cctttcgttc cacctagcca ttctgcaaca gttgctgcca ttacagcata cgttgcagat
    16561 attttaagtc cagaaaaaaa cttatccatt gccataggaa acttaaggtg aatgaatgta
    16621 ttaactttat ttgagttcat agtcttaaat aaatttaaat aatctttatc aatattctca
    16681 ataccatcta caaaacttat taatatagga aaaaaacaag taagcattac catcaatact
    16741 tttggcattg ttccaaatcc aaaccatatc ataaaaagtg gtgctataat tattgtaggt
    16801 atcatctgag taaccaacat aataggataa agacattttt ttattattga tacaaaatcc
    16861 atcaatattc cgattaccaa tgatattata attgcgacta taaaaccaag tactgcttct
    16921 cctatagtaa ccacagaatg catggataaa ttttgataat ctttaaaaaa cacattaatt
    16981 atatctactg gtgttggtag tatatactga ggaacttcta aaactcctac cacagattgc
    17041 caaagaataa gtataaacaa aaatgttgct attggatata tactatcttt gactttatct
    17101 atgatttcta agtttttcat ctatagttag acctccagct ttttcatcta ctctagctac
    17161 tgttatgact ctttcacatc caagattaaa agggatttta tgtacctttt ttaataattc
    17221 aaaaacttca tcaaaatcac cttcaacagt agtgctcatt gctcctattt cacatttaag
    17281 accacttttt tcaatttcag caatacaagc atctactact ttatacattt cttcttcacc
    17341 tttatagggt cttagtggca ttactgctat gtctgcgatt accatttaaa tcactccttt
    17401 taaaataatt aatacctact aggtatattt tgttttttat taaaaaattt tttttactga
    17461 aaagatatta tatttaaata aaagaaaagt cttatccaaa ataggataag acttattttt
    17521 atcttaactg gtctccctac actggcatta tccaaacagg ttcaaagggt cgagataaaa
    17581 tctcctctca gcacattagc tccccgaaat atattatatc ttttctactt gattatacta
    17641 cacttatcat attttaacaa attttttatt tatattagat attttatctg tttaaaaata
    17701 tctaatataa attgcacatt attatatcaa ataaattatc ttaaaacgat aatttctcag
    17761 tatctcctaa aactagatta acgtaatttt ctaatttttg ttttactatt tcaagcatat
    17821 ttggatatat atcaattcca tccaaacatt gtgctaaatt tttatttttg ttcatttaag
    17881 ttacaatcat tactgattaa gcatagtttt tatactacac tcatctttat atacaaaaat
    17941 tccttcaata aattccttaa aattatattc taaataagtg atttcatagt cagattcttg
    18001 attaatctct actacacagg gttcttcttg tggttcacaa ccactatagt aaagaaatat
    18061 catttcgtgc ccaccagaaa tggtattata tatgaccata cctatatagg gttaacacat
    18121 tctactatcc aaaaacgact gccagcattg ctacataagg aatatgtttt ttctgcgtca
    18181 atgacatata gactctctaa gtagaaaatg ttagatgcca ttcgttttgt atggtattat
    18241 caaatttttt tttagatttt tatttcttct tatccttgtc cattattcct tttatgacat
    18301 agtatgcttc gtgagtgaat aattgtaaat aaataatatt cattaagcta aaaatagact
    18361 tctatctgga ttttcaatat ataaaccttt tagcagtatt ttctgtgata atataaatat
    18421 tactcgtcct tataatcaaa atcttcagca attggccttt tatataatat aattatttta
    18481 ttcaatttat ttttgaaaaa taaaatattt ttttaatttt taaaatcttt aatatgtagc
    18541 ttgaaaaaca aaacgttttc ctatatgatg gtaatagtag aataaaacta aataggcaaa
    18601 actagagaaa tttagtgacg caaagctata gggactaaga cttatgaaat gagttatgtc
    18661 agccagttgc caaagagata ttttcttttt gtttttatga aagtttttta gggggatata
    18721 tgatatatgt ttatggataa aatggataga tgtacacata tactaactgc atatatatgc
    18781 agttcacgcg attactgcaa ttttatagac acacaattaa atgattttat actagaatat
    18841 ggagagaatg tggtagaatc ttgtttgcat caggtgatgg tattggtaag cagatataat
    18901 taaagaaatt ttattttcta gaaaaccctt tttagtttta tctacgtttt ataattcatt
    18961 aaaaaactaa ttaaaataag cttcattatc tatttttcat gaagtaaaca gttgagttta
    19021 tctcatatac tgtttacccc aattacataa ttctaataat atagattcca atgatttacc
    19081 acgtttagta gacaaatatt caacttttgg aggaatagta ggataagaaa tcctcttaat
    19141 aagtccatcg ctttcaagat actttaattc ttgtgacagt atcttatgac ttatatgaac
    19201 aacttctttt tttaattgac tataacgtat tggctcttgt tttaaaatat gccataaaat
    19261 aattgccctc catttacttc ctatcacagt catggtaaaa ccaattgaac aattaaaatc
    19321 tttttgtctt tcttcaatat ttggaaattc ttcaaaatta ttatctatat ccatctcaat
    19381 cctctctttc aaaatagtaa gtatctaact aaaaagtgca ttctttttta atgtactaat
    19441 ttgtaatata atcttgattg tagcatagaa ccttacataa tactactttt ttagatgtat
    19501 atgttta
//
LOCUS       DAMKOJ010000065        18977 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000065 DAMKOJ010000000
VERSION     DAMKOJ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18977
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.070"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            167..1084
                     /locus_tag="PC592_002623"
     CDS             167..1084
                     /locus_tag="PC592_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF4056575.1"
                     /translation="MMILIQSRGKMKCKELAEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKTEFNSIVEKIKAVLN
                     TRVKSDTYMDYFTIQPQRNCDYKFEKNKCNEIIRAYTTKRKLWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKNYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVDPDSLRNDILSEIEKMKKIY"
     gene            1162..1899
                     /gene="cas6"
                     /locus_tag="PC592_002624"
     CDS             1162..1899
                     /gene="cas6"
                     /locus_tag="PC592_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF4056576.1"
                     /translation="MKMKIEFSTSCIPISYNSLFMSIIKEAIKKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYVKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGSGLKRKLEFENIDLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNIIYNLGLGFRRAQGFGDVDILEWR"
     gene            1905..3755
                     /gene="cas8a1"
                     /locus_tag="PC592_002625"
     CDS             1905..3755
                     /gene="cas8a1"
                     /locus_tag="PC592_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HDF4056577.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKSNKQAEIFIMEDYIEFDSS
                     FLENFHEYYFNYFMDEYDVSKRIKKSIDYSINFIKSKPDKVKDGIKKIKDTVKQQNDK
                     VKKFDEEKFNLIKEKLDSISKIKSYDEFDSLEILVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDISEKKVSKSSVNTIEKIMKEINKNFIKKNKSIENIKEYMDSLEICEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWKQEYVSSICDVCKLILFCTPAGATYTR
                     KDYLTNEENEFYLFVNMDTSINELFDRNNSLKAQKSESSNSKDENPFNQLIKSIVEEN
                     KLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSN
                     VLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVY
                     KMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFS
                     PSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLSNEKEEK"
     gene            3757..4671
                     /gene="cas7i"
                     /locus_tag="PC592_002626"
     CDS             3757..4671
                     /gene="cas7i"
                     /locus_tag="PC592_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF4056578.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRADGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREAAVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGEIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVVQGTFLGKYLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            4673..5374
                     /gene="cas5b"
                     /locus_tag="PC592_002627"
     CDS             4673..5374
                     /gene="cas5b"
                     /locus_tag="PC592_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF4056579.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LKEIYDSLLNYNEHLSLGRKEDLVRITDIRFVEVNKFEIDEDIQLDDYENYKLSECDI
                     RMPIYIPKTSLQDKDIDGISYRLNNYYDNNAVGDKKRVWNKVDSYYVEDGNTISVGDI
                     LLDNEGDLLYFNNIN"
     gene            5385..7706
                     /locus_tag="PC592_002628"
     CDS             5385..7706
                     /locus_tag="PC592_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF4056580.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGTNINSLNFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIISRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDKKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVMN
                     IGEHTENYLMKEFGSLRETQSFAQSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGKFMIMTATMPTIYIDELKKRGVVDSNLANLTCNTEKIRHCVSIVENSIDENLEQII
                     QSGINKKVLVIVNTVKSAIEKYELIEEIIKSKGIDINVNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKNCMNGKKCFKMKEKHKVQMVKILYSKESLKD
                     TDFEKKFTRALDILDTITPYSLGSNEAQNILRNIEGYTVIPEDIYRKIEKTLIRDYEE
                     LGQELTEAYSNDDRQLINEIKSKRKKARREIIKKTVNLPIYKAKQNIVDIQVKGLEDL
                     KILLYKYDIHEDVHTKHIFGKGVIIGKEIDQFI"
     gene            7721..8272
                     /gene="cas4"
                     /locus_tag="PC592_002629"
     CDS             7721..8272
                     /gene="cas4"
                     /locus_tag="PC592_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HDF4056581.1"
                     /translation="MWLKFTKEGEFVPIDLDLLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMKLSP
                     PKIEKKPYCTKCAYYEFCFVKEE"
     gene            8275..9255
                     /gene="cas1b"
                     /locus_tag="PC592_002630"
     CDS             8275..9255
                     /gene="cas1b"
                     /locus_tag="PC592_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF4056582.1"
                     /translation="MYKDYYIISNGNIKRKENTIYYYNLEGDKKILPVEQVDDIHIYG
                     EVDLNTKLINYISQYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDAIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            9258..9524
                     /gene="cas2"
                     /locus_tag="PC592_002631"
     CDS             9258..9524
                     /gene="cas2"
                     /locus_tag="PC592_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF4056583.1"
                     /translation="MFVIVTYDIVEAKSLNRIRKILRKYLTWTQNSVFEGNITDGKLH
                     KCISEIENIIDNREDSIYIYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   9708..11829
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=9708..9736
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            11890..12318
                     /locus_tag="PC592_002632"
     CDS             11890..12318
                     /locus_tag="PC592_002632"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF4056584.1"
                     /translation="MIRKLNNKDINKIMEIWEESTIKAHGFISKEYWQNNHNAVKNEY
                     IPISDTFVYDIGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATEKYKSLSL
                     AVYKDNKKAVIFYNKKGFNVVKGQLNEDSGFKEYIMEYSK"
     gene            12454..12621
                     /locus_tag="PC592_002633"
     CDS             12454..12621
                     /locus_tag="PC592_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056585.1"
                     /translation="MVTKEENKIVWCISNLTNLPFKNNKFDIILNVLSPVNYKRFERV
                     LNNYGMARKVC"
     gene            complement(12781..13551)
                     /locus_tag="PC592_002634"
     CDS             complement(12781..13551)
                     /locus_tag="PC592_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056586.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLNL
                     NKDNNLDERPILDELNYNTSSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEISNEVSSIRCCNCDELLEDVTLDKLSNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            13875..14420
                     /locus_tag="PC592_002635"
     CDS             13875..14420
                     /locus_tag="PC592_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDF4056587.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRKNL"
     gene            14441..15577
                     /locus_tag="PC592_002636"
     CDS             14441..15577
                     /locus_tag="PC592_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDF4056588.1"
                     /translation="MEEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKHLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKIKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNINNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIKKAELDFWVKESHKRAKEAREEKIFDDIIFPINNSTCDEGIRDKMSQRLLDRMP
                     SILGKESITNAANSCLINDGASFIILCSKKYLEHAKNKPIAKIVNTCTIGTDANLSPT
                     SAIKAMDKLLEIESLSYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALMIERV"
     gene            15581..16972
                     /locus_tag="PC592_002637"
     CDS             15581..16972
                     /locus_tag="PC592_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDF4056589.1"
                     /translation="MNYYELLRIKSDRHKNKNFLIIDGEKYTYENILSYSEEIGKQIY
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNLSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNAIFNISGESILFINGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPIKLQLLVKHLKESVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIERPLSVGRPFPGIDVYIREEKIFVNT
                     EYAVYNATKPYSVNDIGYFDNDGYLIFEGRSDDIVNIGGFKVSSTKIENEVKKIPQIE
                     DAVVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            17048..17923
                     /gene="dpsA"
                     /locus_tag="PC592_002638"
     CDS             17048..17923
                     /gene="dpsA"
                     /locus_tag="PC592_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HDF4056590.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDNCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAISEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTASAFGYSSISLNQLDEKLLQFDYIFNTI
                     PDCILTKERLEKVSQEVTIIDIASSPGGVDYSATKEVGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            17926..18516
                     /locus_tag="PC592_002639"
     CDS             17926..18516
                     /locus_tag="PC592_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HDF4056591.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEDAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(18723..18923)
                     /locus_tag="PC592_002640"
     CDS             complement(18723..18923)
                     /locus_tag="PC592_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056592.1"
                     /translation="MKKLKIISIFSLIISVILTIGGIGIVTYYVNNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT         7680 a         1789 c         3181 g         6327 t
ORIGIN      
        1 aacaaatata aagtataata tgataaatgt caaaattata aaaaagttct acttatataa
       61 aatataaaga ggttatatgt acatatgtgt agaaataaat aataaaaata tcgattaatg
      121 ttattagggg gtgttactca ttagtaaatt agctaataca cttagaatga tgatattaat
      181 tcaaagtaga ggcaaaatga aatgtaaaga gttggcagaa gagttagaag taagtgaaag
      241 gcaaataaaa agctataaaa tgtacttaga gcaagctggt atatttataa attcaacgcc
      301 tgggatttat ggtggttatg aaatagataa atgtaacagc atctcattaa ttaaattatt
      361 agatagtgaa gtttcaattc tagatatgat aaattcacag ttagagtaca ataatgatat
      421 ttacaaaact gaatttaata gtattgtaga aaaaataaaa gcagtattaa atacaagagt
      481 aaaaagcgat acatatatgg attatttcac aatacaacca caacgtaatt gtgattataa
      541 gtttgagaaa aataagtgta atgaaataat tagagcatat acaacaaagc gtaaactttg
      601 gatagagtat tattcattga actcaggcaa tagtgagaga attgttcatc catatggttt
      661 gtttaattat aagtcagata cttatatggt ggctttttgt gaaaaaagat ttaagtttat
      721 agactttaaa ttatgtagaa ttaaaaatta taaggtttta gaagaaaagt ataatgtaga
      781 caaaagtttt agttgggatg aatatagtaa aaatagtata ggaatttata agggagaaga
      841 aattaatgtt gttataaaaa ttagtcatcc attttcaaca attataaagg agaaagtttg
      901 ggttaataat caacaaatca tagaatatga tgataaatct ataatgttta aagctaaaat
      961 gagaggttat gaggagataa aaagttggat tttaagtatg ggagcttatg ttgaggttgt
     1021 agatccagat agccttagaa acgatatatt atcagagatt gaaaaaatga aaaaaattta
     1081 ctgatttttt caaataattt atacttggac caatatactt cacggtctag tgttaatata
     1141 ttaattaaga gaggtgatat tatgaaaatg aaaattgaat ttagtacaag ttgtatacca
     1201 atatcttata attcgctctt tatgagtatt ataaaagaag caataaaaaa atctaatgaa
     1261 gattactata aaaacatgta ctattataaa gaaaagaata ataaaaaaac taaaaatttt
     1321 acattttcgg tttatgtaaa aaagtatagt attgaaggcg acaattttat tatagaagat
     1381 aaagtaatat taaatataag tactccagat ttagaattgg gttttcatat atataatggg
     1441 ttaatgactt ctaaaaaatg cttatataaa gactatgaac ttacaagaat tagaatcgat
     1501 ttatcaagag aaaagaaggt aacagaagaa agggtactat ttaatgcatt gtctccaatc
     1561 tgtgtaaagt ctaaagaagg aaaattcttg gagataactg atgatagata catagaagaa
     1621 ctaaactata taactaatga agtggttaaa aattataggg gtagtggatt aaaaagaaag
     1681 ttagaatttg aaaatataga tctcaaaaag gtagtagtta aagagagttt aagagaattt
     1741 aaaaaaataa caggtaaaga gtatcaatat attaatggtt ataaaggtaa atttatattg
     1801 aaaggtgata ttgatgattt aaatattatc tacaatctag gacttggctt taggcgtgct
     1861 cagggatttg gagatgtaga tattttagaa tggaggtgag ataaatgaag ttaagagttt
     1921 atagaggaga ttggtttttt aatatgggta tagttggatt tttaaatata ataaagaaat
     1981 caaataaaca agcagaaata tttattatgg aagattatat cgaatttgat agttcatttc
     2041 ttgaaaattt tcatgaatat tattttaatt actttatgga tgaatatgat gtatcaaaaa
     2101 ggattaaaaa aagtattgat tacagtataa attttattaa atccaaacct gataaagtca
     2161 aagatggaat taaaaaaatt aaagacaccg taaaacaaca aaatgataag gttaaaaaat
     2221 ttgatgaaga aaaatttaac ttgataaaag agaagttaga tagcatttct aagataaaaa
     2281 gttatgatga atttgatagt ttagaaattt tagtggatga gactatagat atatttaaaa
     2341 taaaatcaat aaatgacagg cttacagcaa atctttataa atatgtagtt caagataatt
     2401 attttggaca agttagtttt tttaatgttg ctaaggctaa gttagatttg gatggattaa
     2461 aacaggtaat gtttaatgat tatttaagac aaattatata ttttggagag ttagaagatt
     2521 tattagaaga gaatgactat gacaagttga aaaactattt gaatgataga ttaaatagta
     2581 tagctaagga tataagtgaa aaaaaagtta gtaagtctag tgtaaatact atagaaaaaa
     2641 ttatgaagga aataaataaa aactttataa agaaaaataa aagcatagaa aatataaaag
     2701 agtatatgga tagtttagaa atatgtgaaa tgtgtggttt atataaagga atattagatg
     2761 aatactcaga aagtaatttt gctccacttg gagtaagtac caataatgct aggaatatgt
     2821 tttggaagca ggagtatgta tcatcaatat gtgatgtttg taagttaata ttgttctgta
     2881 ctccagcagg ggctacttat acaagaaagg attatttgac taatgaagaa aatgagtttt
     2941 atttatttgt taacatggat acttctataa atgagctttt tgatagaaac aatagcttga
     3001 aagctcaaaa aagtgagtct tcaaattcta aagatgaaaa tccttttaat caacttataa
     3061 aaagtatagt agaagaaaat aaattaaaaa gtgaatggca acttcgtaat atactttttg
     3121 ttgaatttaa agcaagtata gattctaaaa aatgtaaaat aaattatttt aatattccaa
     3181 cttatttagc aaagtttttt gtaaaagaaa ataaaaaaat acaaagtata tatgattata
     3241 aacttaaatc aaatgtatta gatttaattt taaaaagtaa agacttaaaa catttaatta
     3301 ataacacttt aaggaatata gttaagagta atttagaaag taataataaa tcaaacatat
     3361 cagggttatc ttgtttcaat gttgttcaat taagaacaat attaaataac tataagagag
     3421 gagtgtataa aatggactat aaaaagttga gaaagattta tgagtcaggt tgtgaaatac
     3481 atgattatta tattgataag aatgctaaaa ataaaataga aggaataaca tataaaattt
     3541 taaatttaat taaggttggt aataaaaatg attttatgca aacaatttta aggatttttt
     3601 caccaagtga aaaaacacca ccagaagaaa ttttacagat atttgttgaa gaagatttag
     3661 attttgaatc tgtagggtat gcatttgtaa caggattaat ttctggaaaa tatgaaggaa
     3721 aagataaact atcaaacgag aaggaggaaa aataagatga aaagaggatt aacatttaca
     3781 gtaatagcac aagctcaaag tttaaactat ggtgaaggga taggtaatat atcagaatta
     3841 aaaaaattaa gtagagctga tggaaatata tatacatttg catctcgcca gtgtttaaga
     3901 tatgacatag tacgattagc agcagaattg tttaattgga atttacaggt tgtcgataaa
     3961 gaaaaaggta ctattcaatt taaagataat ataagtataa gagaatcaga agaaatggat
     4021 ttatttggat atatgaaaac aaataaaaaa gatgagaaag ataaaaaagg aggttctttg
     4081 actagagaag ctgctgtaag attaagtaat gcgatttccc ttgagccata tagaagtgac
     4141 atggactttt taaataataa aggattagca gatagaatag gagaacatcc taatcttgct
     4201 aacatagagc aacatttaag ttattataca tatacagtga ctatagattt atctaaaata
     4261 gggaaggatg gagagataga acttgataat aaagagaaat gtagaagagt agtagaattt
     4321 ttagaaataa taaaagtatt gaatagaaat attagaggta gacaagaaaa tttatctcct
     4381 ctatttgtag taggtggagt atatgaaata gcaaatccat ttttcttggg tagaattaaa
     4441 ttaaaaggag ataaaaatgg atttaaaata aataaacaag ctatagaaga agtagtccaa
     4501 ggtacttttt taggaaaata tttaaaagaa tttacctatg ttggaatggt agatggggta
     4561 tttataaata aagaagaatt taagggattg tttgaagata attttttaag tgtagataaa
     4621 ttttttggac aactagttaa agaagtaaag gaatattatg gggtgaatta atatgaaggt
     4681 tttgaaatta gatttatttc aagaaactgc atgctataaa aaaccatttg ctatgaagat
     4741 tacagagaca tatccactgc ctccatattc tacaataaat ggattaattc acaaaatatt
     4801 aaatgctaca gaatatatac catttaatat aagtgtacag ggaacatatg aaagtatatt
     4861 taataattat cagacgacat atttttataa aaaagatagt attacatcta tgccaatgaa
     4921 tagtcatatg ctattgaatg taaatttgat aattcatata ggtggggatt ttgatttatt
     4981 gaaagaaata tatgatagtt tattaaatta taacgagcat ttatcattag gtagaaaaga
     5041 agatttagta agaattactg atattagatt tgtagaagtt aataaatttg agatagatga
     5101 ggacatacaa ttagatgatt atgaaaatta taagttatca gaatgtgata taagaatgcc
     5161 tatatatata ccaaaaacaa gtttacaaga taaagatata gatggtataa gttacaggct
     5221 caataattac tatgataata atgctgtggg agataaaaaa agagtttgga ataaggtgga
     5281 tagttattat gttgaggatg gaaatactat atcagttgga gatatattat tagataatga
     5341 aggagattta ttatatttta ataatataaa ttaggaggga gagtatgtta tatgctaaat
     5401 ctaatccagt ggaaactttg agagaacata ctgatgaact tttaaaacaa atgaatgtgt
     5461 taagagaaag ttatggaaca aatataaata gcttaaattt tctagaggag gagatatttt
     5521 ggcaattact tgactttgtt atagaatttc atgatattgg aaaagcattt tcaccatttc
     5581 aagagttaat aataagtaga atggatacta aaataaatga acctaaaata gtaactcatc
     5641 tagaaaataa tgtaggtcat aattatcttt ctcctgcatt tattgattat agttatatag
     5701 acaagaaaaa aaataaagaa cttagagcag tattaaatca agttattgta tatcatcatg
     5761 aaagagatat ctttatagat aaagatttta aaaatttaat acaaaaaata ttagatgaag
     5821 atttaataaa taaagtttat gaactacagc atgaatttaa agttagatat ccaataaaaa
     5881 cagaaaaatt gagtaaagta tatttacaaa gtgtagaaaa aagaatagat aaaaatcaca
     5941 agtactataa tttatatatt atgttaaaag gaatactaca taggctagac catagtgctt
     6001 ctgctcatga agttgtggaa tgcaataatg ttatgaatat aggagaacac acagaaaatt
     6061 atttaatgaa agaatttggt agtttgagag aaactcaatc atttgcccaa tctaatagaa
     6121 ataagaatat aatactgatt gcatctacag gaatgggaaa aacagaaact gccttaattt
     6181 ggatagataa agacaaggca ttttttacac ttccattaag agtaagtata aatgcattat
     6241 ttgatagagc aaaaaatata gttggagttg gagaatcaaa tgatacattc ttaggattgt
     6301 tacattcaac agcaatagat tatctggaag aaagtaatca agaaaattca agtgagattg
     6361 tagatttagc aaagttatta tcctgtaagc tgacattttc tacaatagac caaatattta
     6421 aatttccttt tttgtataga gggtatgaaa aagtgtactc aacattagca tattcaaaag
     6481 tagtaataga tgagatacaa gcatattcac cagaaatagc agctgtattg gtaaaaggta
     6541 tagaaatgat acataaaata ggcggaaaat ttatgataat gacagccact atgccaacta
     6601 tatatataga tgaactaaaa aaaagaggtg tagttgacag taacttagct aacttgacat
     6661 gtaacacaga aaaaataaga cattgtgtgt ctattgtgga aaattcaata gatgaaaatt
     6721 tagaacaaat aatacaaagt ggaataaata aaaaagttct tgtaatagta aacacagtta
     6781 aaagtgctat agaaaaatat gaattaatag aagagataat taagtcaaaa ggaatagata
     6841 ttaatgtaaa tcttttacat tctatgtata tacaagaaga tagagcaaag ctagaaaaat
     6901 atataaaaga atttgcagat agtgatagta atggtatttg gattactaca caattagtgg
     6961 aagcatccct tgatattgat tttgatgaac ttcatacaga aaattcaaca cttgacagct
     7021 tatttcaaag atttggcaga tgttatagaa gtcgtgagta tgaagaaaat agtccaaata
     7081 tatttatata tacagaaaaa gctacaggaa taggtagtat ttatgataaa gatattgtag
     7141 aaaaaggact tgagctattg aaaaactgta tgaatggaaa aaaatgtttt aaaatgaaag
     7201 aaaaacataa agtacaaatg gttaagatac tatattctaa agaaagttta aaagatacag
     7261 attttgaaaa aaaatttact cgtgctttag atatattaga tacgataaca ccatatagtt
     7321 taggctctaa cgaggcacaa aatatactta gaaatattga aggatataca gtaataccgg
     7381 aggatatata taggaaaatt gaaaaaactt taataagaga ttatgaagag ttgggacaag
     7441 aacttacaga ggcatatagc aatgatgata gacaattgat aaatgaaata aagtctaaga
     7501 gaaaaaaagc aagaagagag ataattaaaa aaactgtaaa tttaccaata tataaagcta
     7561 aacaaaatat agtagatata caggtgaaag gtctggaaga tttaaagata cttttatata
     7621 aatatgatat acatgaagat gtgcatacaa aacatatatt tggcaaaggt gtgattatag
     7681 gtaaggaaat agaccaattt atttgatttt tatattaaca atgtggctaa aatttactaa
     7741 agaaggtgag tttgtgccaa tagatttaga tttattgaaa gttcaaggtg taaagataaa
     7801 ttattattat gtatgtaaaa gaaaactatg gctattttct aaaggaataa ctatggaaca
     7861 aaatagtagt agagtattgt ctgggaagat agtacatgaa gattcatata aaagaatgaa
     7921 aaataaagaa atgttgattg atgatatctt gaagctagat ataataaagg acgagtatgt
     7981 aaaagaagta aaaataagtt caaagatgaa agaagcagat gaaatgcagt tatactatta
     8041 cttatactat ttaaagaata gtatgggtat agagaaaaaa ggaactataa attatgttaa
     8101 ggaaaagaaa caagaagaat tgatattgac agaagaaaaa gaaaggatta ttgaaaacac
     8161 acttataaat ataaatgaaa taaacatgaa attatctcct ccaaaaattg agaaaaaacc
     8221 ttattgtaca aaatgtgctt attatgaatt ttgttttgtg aaggaggagt aacaatgtat
     8281 aaagactatt atattataag taatggtaat ataaaaagaa aagaaaatac aatttactat
     8341 tataatttag aaggtgataa gaaaatatta ccagtagagc aagttgatga tattcatata
     8401 tatggtgaag ttgatttaaa cacaaaactt ataaattaca taagtcaata tggagttatg
     8461 cttcattttt ataattacta tggatattat tcaggtacat attatccaag gaagaaaaat
     8521 gtatcaggat tcagtttagt atgtcaatca gcctgctatt tagataaaaa tgaaagatta
     8581 tacttagcaa aatcctttgt ggaaagtgca tcataccata ttttaagaaa tatgagatat
     8641 tacaaagttg atgaaagttt aattgatgct ataaaggatg aactaaatga tttgaatgat
     8701 gtcaaagaaa tatctgaact tatgggtaaa gaaggtagaa taagaaaaac atactataaa
     8761 tcatttaatc aaatattaaa agatgacttt gaattttata aaagagaaaa aagacctccc
     8821 aaagacccag taaatgctct tatgtctttt ggaaatagca taatgtatac taatgtttta
     8881 agtgagatat ataagacaca acttgaccct acaataagct ttttacatga accatcaaca
     8941 aagagatttt ctttaagttt agatattgca gaaattttta agccaattat aattgacaca
     9001 ataattttta gcctgattaa taataaaaga attaataaga atgattttga atatcaagat
     9061 aaaatttgtt atttaagtga aaaaggaaag aagaaatttt tgcaagaatt tgaaaataag
     9121 atgcagacaa ccataaaaca tagaaatcta aatagaaaag tttcatatag aatgtttata
     9181 agattagagt gttacaaatt aattaaacat tttataaatg atgaaaggta caaagtttta
     9241 aaggtgtggt ggtaagtatg tttgttattg ttacttatga tattgttgaa gcaaagtcgt
     9301 taaatagaat tagaaagata cttagaaaat atttgacttg gacgcaaaat tctgtttttg
     9361 aaggcaatat tactgatgga aagttacata aatgtatttc tgaaatagaa aatattattg
     9421 ataatagaga ggattcaatc tatatttatg agataaaaaa tcctaattca attaaaaaga
     9481 aatgctatgg tattgataag tattctgatg aaatgtttat ataggtttgc agtgagcgac
     9541 atttatgcta aaataggtgt taacagttgg aatataaggg attgaaggtg tatgataact
     9601 gttatcaatt gcactactgt tcgctcactg caaattttga tgtttttatt gaattataat
     9661 tgcttgattg aagtattttc aatgtattca attacaccta ttttggggtt ttatattaac
     9721 taagtggtat gtaaagcaat atattctagc aggagcagat ttaggagctt tacaagtttt
     9781 atattaacta agtggtatgt aaagattctt tatacagaga aacacgatac tatttacagg
     9841 ttttatatta actaagtggt atgtaaagat atctttgtac tcttgatttt ccagctttga
     9901 tatagtttta tattaactaa gtggtatgta aagaattgca taatattaga gagtttaata
     9961 ccatcaagtg ttttatatta actaagtggt atgtaaagga tggtaaaatg ggagatactt
    10021 tctttggatt aacaggtttt atattaacta agtggtatgt aaagttgctt atacttacaa
    10081 ctttttctgc tgtagcatgt tttatattaa ctaagtggta tgtaaagaaa actgtttcta
    10141 cttttttagt cccaagtaat tccgttttat attaactaag tggtatgtaa agcgcatttt
    10201 tgcttttata ttgcttcttc tatcttctag ttttatatta actaagtggt atgtaaagtc
    10261 taaaatatcc tcacaactcc tgtaattgta ttttctgttt tatattaact aagtggtatg
    10321 taaagtggtt tactaagaaa ataacggatt tttaagagaa aagttttata ttaactaagt
    10381 ggtatgtaaa gtttgatgaa aaagaagaat ataagaggga tgtggcaagt tttatattaa
    10441 ctaagtggta tgtaaagtaa ctccaaactc cgtaagtctt gccatttctc caagttttat
    10501 attaactaag tggtatgtaa aggagtatca agagaccagg gaaaggcagg taaagcaggt
    10561 tttatattaa ctaagtggta tgtaaagaat ggtaaaatga aggcataata aatttcaata
    10621 taggttttat attaactaag tggtatgtaa agagagacag tttaaaacta aatcagaaga
    10681 aaagtcttat agttttatat taactaagtg gtatgtaaag tttaaagcac ccttaaaatc
    10741 tggttgggca tgttctcgtt ttatattaac taagtggtat gtaaagttgg tagacaacct
    10801 ggtacttggc ttaagattga taagttttat attaactaag tggtatgtaa agcatgtgat
    10861 agagataata tacaatatga tagagaaagt tttatattaa ctaagtggta tgtaaaggca
    10921 taaaatacct tcaaaaatag cttctactga cagttttata ttaactaagt ggtatgtaaa
    10981 gcgaaataat gttttgtttt cgatgggtat atatacgggt tttatattaa ctaagtggta
    11041 tgtaaagtag cttttgcgac tggaagatac gcagataatt tagttttata ttaactaagt
    11101 ggtatgtaaa gattgtaagc tctttaattt ctaaattagc tccgattgtt ttatattaac
    11161 taagtggtat gtaaagttaa gtagagcaat gtatcatggt tatgtgaaaa gtgttttata
    11221 ttaactaagt ggtatgtaaa gctagtaaat tttgctaaaa ggcactatta ttgtagtgtt
    11281 ttatattaac taagtggtat gtaaagcagt tgacacaatg agtaaaagcg aagcagagca
    11341 agattttata ttaactaagt ggtatgtaaa gttatgttat aggagcaggt tgcaagaagt
    11401 ataagcaagt tttatattaa ctaagtggta tgtaaagcat agattttgga gatttaaggg
    11461 aaggcaatat gtgtgtttta tattaactaa gtggtatgta aaggggtttg catctttatt
    11521 agataatttt attaatagag ttttatatta actaagtggt atgtaaagta aatatagaat
    11581 aaagcatttt agtttacaat gcaagtttta tattaactaa gtggtatgta aagacctaaa
    11641 aaatcaatgc agcttatctt atatgcaatg gttttatatt aactaagtgg tatgtaaaga
    11701 ttaaggaata gtaattacag tggactggag ttagtgtttt atattaacta agtggtatgt
    11761 aaagacgttt cgcaagggat tttttaaagc gaatggataa gttttatatt aactaaatca
    11821 tatctaaata aaatacactt acctataaac atgataaaat caatacaaaa atgaggtgaa
    11881 acaaaattta tgataaggaa attaaacaat aaagatataa ataaaatcat ggaaatatgg
    11941 gaagaaagca caatcaaagc acatggcttt ataagtaaag aatactggca aaataaccat
    12001 aatgctgtta aaaatgagta tatacctata tcagatacat ttgtatatga tattggagat
    12061 gaaataaaag gatttataag cataatagat aaaagtttta taggagcttt atttataaag
    12121 cccaaatacc aaaatctagg tatcggaggt aaacttttag attatgcaac tgaaaaatat
    12181 aaaagtctaa gtttagcagt atacaaagat aataaaaaag cagttatttt ttataataaa
    12241 aaaggtttta atgtagtaaa agggcaatta aatgaagact caggatttaa agagtacata
    12301 atggaatata gtaaataata tgagtgtatt ctattaaaaa gataattaat ctatttgata
    12361 tttgattaga ggcattttta taagagtaat ttttttaata gattatataa agataaatat
    12421 atttgttata tatgtaagtt aatcagaatt gctatggtta caaaagagga aaataaaatt
    12481 gtatggtgta tttcaaattt aacaaattta ccatttaaaa ataataagtt tgatataata
    12541 ttaaatgtac tttcacctgt aaactataaa agatttgaaa gagttttaaa taattatgga
    12601 atggcaagaa aggtttgtta aaatttaata attattagat tatagaaagt tgccataaaa
    12661 ttagttcagt aagaactagt ttcatggcaa ttttaattct tatgagagta tttattttta
    12721 catattttaa aaacttatac agtataataa tgtaatctta ctatatcagt ctatagatat
    12781 ttaaatctta aaatgttctc tttgagataa gtttatttca gagtcacaat ttccacaaca
    12841 gtaagatgtt gagacatctt taaatttctc agtattctca tcaaagttca tttttttctt
    12901 tgcaataatt cctaccttgg ttaaattaga gccacaatta ttacagtttt gaattttgca
    12961 taggttagat agtttatcaa gtgtaacatc ttctaataat tcatcacaat tacaacatct
    13021 gatagaagaa acttcattag atatttcaat aggttcagct tctttagaag aaaatttata
    13081 tgttatgtca tttgatactt tataacctgt gtcaaatata ttagaattac aacttggaca
    13141 taggtacttt ggaagatata tatctttttt ttcaaaagta tcactactag tattatagtt
    13201 taattcatct aaaattggtc tttcatctag gttattatct ttatttaagt ttagaagata
    13261 attataaatt tttttatctt cattctgttt tgatgtatcc aacaagtgtt ccattatatt
    13321 agtgtatttt ttattttttg aaggcatgtt taaatccaga taattgtttt caatagcaaa
    13381 gcacactata ttgaaatagt tatatttaac tgcaaaaaat aataacattt catcaaatac
    13441 tttatctatt attttgtcag aaatacttat ccaaaaatct ggtgactcta agtaaacttt
    13501 cctactaagt tcatctaact cttcatctat attattttca ttaactttca tattatcact
    13561 tccttttaaa tatcttgtgt ataaactatt tgttactgtt ttttatataa aataaaatct
    13621 tatataaaaa tatatcatat tataatttac aagtatagtc taaatagagc tgtttttaag
    13681 caaagtctta taaatgacta ttaaaacata aagtaacagt gtaaagttta cttataaatt
    13741 aaatgtaaac ctaaatactt ataagggttg acaaaaaaac gcctttattt tatactaaaa
    13801 caaagcttta atagaagctt tgtatatgta catataaact aaattgaata agacatatga
    13861 agggaattat aaaaatgaaa aatactaaag taaatattca agatttaact aaaatgtcaa
    13921 tatgtgtagc attattgtgt atatcatctt acatatatat accattgcca tttactccag
    13981 caggagtaac agcacaaaca ataatgataa atttgatagc tttgatttta acaccaagac
    14041 aagcatttag tacagttggt gtatacataa tgataggttt aattgggatt ccagtatttg
    14101 gtggaggtac atctggtatt ggaaagttgt taagcccaac aggtggtttt tattttgggt
    14161 ttttgtttgc agcactaatt attagtttat taaaaggacg aaataatgat attaagagat
    14221 atatactaat aacaattttt gttggaatgc ctattatata ttttatggga acagtgttta
    14281 tgtgctattt taatcaaatg acagtagaag cagcactttt tgcagcagta gtaccatttt
    14341 taattggaga tacaataaag tcagttattg cgtctttttt aggtactaaa ctgaacaatg
    14401 tactcagaaa aaatctataa tataaggaag ggtgtaatat atggaggagg tttttatatt
    14461 aggaggattg agaagtcata taggtctaaa aaatggaatt tttcaatttg ttcaacctga
    14521 attactagga gcaagtgttt taaaacattt aattaagaag tatgaaattg ataaaattga
    14581 tgagattata tgtggaaatg ctgttgggac aggagggaat atagctagat taatgacttt
    14641 aacagcagga gtgtcaaatg aagtgcctgc ttttactgtg gatatgcaat gtgcttctgc
    14701 tatgatgagt atagacatag ctttttcaaa gattaaatct gggcagtgtg atttaatcat
    14761 tgcaggtggt tttgaaagta gttctctaca accaatgcgt acatatcata agaatgataa
    14821 gcgatataat ataaataatc caaattatac agttgctcaa ttttctcctg atgataatag
    14881 ccaaaatagt atgctagaag gggcagaaag agtagcagag ttatatcaaa ttaagaaagc
    14941 agaattggat ttttgggtaa aggaaagtca taaaagagca aaagaagcaa gagaagaaaa
    15001 aatatttgat gatattatat ttcctataaa taatagtaca tgtgatgaag gtatacgtga
    15061 taagatgagt caaagattat tagatagaat gccatctatt ttaggaaaag aaagtattac
    15121 gaatgcagca aattcatgtc ttattaatga tggagcttca tttattatac tatgttctaa
    15181 gaagtatcta gaacatgcaa aaaataagcc tatagcaaaa attgttaata catgtacaat
    15241 agggacagat gcaaatttaa gcccaacatc agcgataaaa gcaatggata aacttttaga
    15301 aatagaaagc cttagttatt tagatgtatc tgctgttgaa tttaatgaag catttgcagt
    15361 tatagatgtg ctgtttcaaa gaaagtatcc agagttaata gatagatata atatatttgg
    15421 tggagcttta gcgtatggac atccttatgg tgcttcaggt gcaattattg cattacatct
    15481 tttaaaagca ttagaaaaga ctaagggtag atatggaatt tgctctatag ctgcagctgg
    15541 tggtctaggt tcagctttaa tgattgagag ggtttaaatt atgaactatt atgaactttt
    15601 aagaataaaa agcgataggc ataaaaataa aaatttttta attatagatg gagaaaaata
    15661 tacttatgaa aatatattga gttatagtga ggaaatagga aaacaaattt atttaggtga
    15721 aaatattcct attttaatat attctaaaaa tataatgttt cagttaatta gtttttttgc
    15781 tattaattat tcaaaaaata ttcctattat ttgtcattat aatctttcta aaaaagtatt
    15841 agatgatatt ttactaaaaa ataatatttc aatcattata tctgatgaat ctatggacgt
    15901 tattgattta tatgatgata acaataatga agtagcaaaa aaagttaatt tgtctatttt
    15961 taatcctaaa ttcaatatat atatgtatca atataagaaa cttataaatt atttagataa
    16021 aagcatttgt atgggagctt tatcttcagg ttctacaagt gttccaaaag tattatatag
    16081 aacgtatgag agttgggctg gattttttcc tatacaaaat gctattttta atatctctgg
    16141 ggaatcaatc ttgtttatta atggaacact tagttttaca gggaatctaa attctataat
    16201 gtcagtatta tatgaaggag gtagtattgt aataagttca ggtcttaatt gtaaatcatg
    16261 gattaggaca ataaaacaat ataatgtaac taacatatat cttataccta taaaacttca
    16321 acttttggtt aaacacttaa aagaatcagt actcaaagtt gtaagtattt ttacagggtc
    16381 tcaattatta tttgaagata ctgcaagaaa tctaaaaaaa tatatgccaa agtctgaaat
    16441 tattttatac tatggggcaa gtgaattaaa ttatattaca tatttatgct atgatgaact
    16501 aattgaaaga cctctaagtg taggcagacc atttccagga atagatgtat atattagaga
    16561 agaaaaaatt tttgtgaata cagaatatgc agtatataat gcaaccaaac cttattctgt
    16621 caatgatatt ggatattttg ataatgatgg atacttaata tttgaaggaa gaagtgatga
    16681 cattgtaaat attggaggat ttaaagttag ttctactaag attgaaaatg aagttaaaaa
    16741 aattcctcaa attgaagatg cagttgtatt gccgtattca gacactataa gaggaaatca
    16801 aattgtatta tttgtaataa ctatagacaa aattacgaag aaagatttgt tgattaaaat
    16861 gaaagataat ctaatgaaaa atgaaatccc aaagaaaatt atctttttaa attcatttcc
    16921 atatacctct tctgaaaaga tagatagatt agcattatta aaaatgttat aagtataata
    16981 tttagtaatt ttagtgaacc aatgtattga taaaaacata ttgtatatag taaaggaggc
    17041 ttacaatatg tcaaatcaat acgatataac tgttattggg ggagacctgc gacaagtgta
    17101 catggtaaaa aaactaatta ataaagggta ttctgtagtc acttatggga tatcaaatga
    17161 aattataaat ggaatcgttg gaaaatcaac ttcactagct gaagcactat ccaaaagttc
    17221 cattatttta tgtccgattc catttacaaa gaatcaagtt aacattgaaa atactgataa
    17281 ttgtcttgat gctactattg ataacttgct aattaattta tctcctaatc aaatcttatt
    17341 tggaggtaac ataccaacta aagtttgtaa attttgcgag caacactcta ttcagattta
    17401 tgattttatg aaaatgaatg atgttgctat tttaaatgca gttgctacag cggaaggggc
    17461 tatatcagaa gctattaaaa gaagcataat caatatacat caaagtaact gcttagtatt
    17521 aggttatgga agatgtgcac aaatacttgc aaaaaaatta tatgctttgg atgcaaatgt
    17581 atgtgttggt gcaagaaata atgatgcaag aagtacggct agtgcatttg gatattccag
    17641 tatttcttta aatcaacttg atgaaaaact tttacaattt gattatattt ttaacactat
    17701 accagattgt attttgacta aagaaagatt agaaaaagta tcacaagaag taactattat
    17761 agatatagct tcttctcccg gaggagtaga ttattctgct actaaagaag tagggattaa
    17821 tgcgactctt tgtcttgggc ttcctggtaa atattcacca aagacatctg gtgaaattct
    17881 tgttaacgct atagaaaata ttataaatga aagaagggat tagaaatgag acttgaagga
    17941 cttacaattg gagtaggatt tactggttcg ttttgtactt atgataaaat atttatagag
    18001 ttagagaatt tggttaaaga aggagctaat gtccacacta tattttcaga tgtatcacaa
    18061 aatatagatt gtagatttgg aaattctgaa gagtttatga aaaaagcata tgaacttaca
    18121 ggaaataaac ctatagttac gattgaagat gcagagccat ttggacctaa gggaattgct
    18181 gatattataa taatagctcc ttgtactgga aatactgctg caaaattagc aaatggtatt
    18241 acagattcac cagtattaat ggcagcaaaa ggtcatcttc gtaatgataa accactagta
    18301 atatcaatat caacgaatga tgctctaagc tttaatttca aaaatattgg tattctcctt
    18361 aattctaaaa atatatattt tgtacctttt ggtcaagata attgcaaagc aaagcctaat
    18421 tctatgattg cacatactga gctaataatt ccaactatag aacttgccct agagaataaa
    18481 cagctacagc ctgttataaa aagtccacat caatagaatt ggttctataa tattatgtat
    18541 tagatgcaag actagcaaag aggctgtctc aaaatagaga taagcctctt tttcattgtt
    18601 gaaatgatga aaatatattt aatttcatac aaaaaaatgc cttatggact aaaaagtcta
    18661 ttttgagcta atctccataa tttttggtat attaaaattg tttacttaat ctaattttta
    18721 aattagaatt tatatcgctt tgactcttca aatatcaatc taactgttgt tgatacaaaa
    18781 gaagaggaca taattaaaac aaatactgat agtcctctaa taaacaaatt atttacataa
    18841 taagttacta ttccaatacc tccaatcgtt aaaattacac ttataatcaa agaaaaaatg
    18901 ctaattattt ttaatttttt catgattatc ctccttctta taaatttcaa atttatctat
    18961 ataatattaa atatatt
//
LOCUS       DAMKOJ010000066        18697 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000066 DAMKOJ010000000
VERSION     DAMKOJ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18697
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.071"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            212..1813
                     /locus_tag="PC592_002641"
     CDS             212..1813
                     /locus_tag="PC592_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HDF4056593.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADRQTYETVILVNTEKSLADGLSASGLSGVTKAPILFTQKNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELNSKNIEVKRIGGEDRLKTSYLMAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKGIPFDVKNVQSYCIGSEEIMSNSLVKNTNSVR
                     IEGTDRFETNKNVIDYFFKNADGFYVSDGYQLVDAIAAAPLTKDSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVVQQCTNASKSNGQPPTITIGNIEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTEKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKETLLVSSKLEDMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKKVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            2031..3620
                     /locus_tag="PC592_002642"
     CDS             2031..3620
                     /locus_tag="PC592_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4056594.1"
                     /translation="MKVNKRILSIGLTISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGAVKAPILLSQRNNIPPDTEKMLKDVKKA
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGDDRIETSYLIAKEIASIKSINKVFITNGY
                     TGEADAMSASSVASRDGAPIILTDGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNILAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSINVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYNLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILSNGEVYATQEFLNK"
     gene            3833..6013
                     /gene="slpA"
                     /locus_tag="PC592_002643"
     CDS             3833..6013
                     /gene="slpA"
                     /locus_tag="PC592_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HDF4056595.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPVFAADEQVKYQNTYTVVQSKYEK
                     ALKDMQKGITDKKIKSIAISYEGKPVTTITVADMDTKGKTSTKEELASALLKTTVNDK
                     LDNLGDGDYVDFDITYVGDADRLTAGDLNTFAKGIADSTEKKIPAAKGSNYGVAKTNS
                     GTGKLTTDTEAVISTSIEGKVEGNNLTISLKDAPSKVGVIGANNDTLADVTFADDAKL
                     TVSVGDPKIDLAKSFIFDTKTGKLGGIVEKENDATEHAYVRVINAKEQTIDLDASSYK
                     SAEDLAKAYAFDVNELKTLYTEIEAYQKDSNNKTDKVQIVDGKYQTILYAEGKRLTTK
                     SATQASKLADENSPLKLVIKADKLKDLKDYVEDLRNANNGYSNTVTVAGDDRIETAIE
                     LSSKYYNNSDEDNAITEDAVNNVVLVGSQAIVDGLVASPLASEKKAPLLLTSKDKLDS
                     NVKSEIKRVMNLKTTTGINNSKKVYLAGGVNSISKEVENELKDMGLKVTRLSGDDRYA
                     TSLEIADEIGLDDDKAFVVGGTGLADAMSIAPVASQLNEKGDATPIVVVDGKAKELSS
                     AAEDFLDDSQVDIIGGKNSVSKDMEDAIDDATGKSPNRVSGDDRQETNAEVLKESDYF
                     PDGAVNYFVAKDGSTKEDQLVDALAAAPVAANFGRTYNIKDNDSSGTVSPAPIILATD
                     SLSSDQNVAISKALPSGKSGDNLVQVGKGIANSVITKIKDLLDM"
     gene            6213..8558
                     /gene="secA"
                     /locus_tag="PC592_002644"
     CDS             6213..8558
                     /gene="secA"
                     /locus_tag="PC592_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF4056596.1"
                     /translation="MSVLDTILDKADEQEIKKLNLIVDKIEALEEKIQNLSDDELKEM
                     TNVFRNRLNNGETLDDILMEAFAVVREVSKRKLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYESLGMTVGVIIANQD
                     QNIRKQQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGDGDEDLKLYELANSFIKTIKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEINNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPVIRADLHDKVFKTEEEKYNAVVEEIIRIHKTRQPILVGTVSVEKSEKLSRMLKK
                     QGIKHQVLNAKQHDKEAEIISKAGKLDAITIATNMAGRGTDISLGAGDREEEQQVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NNEDIQEDIQKMVKDIIQEAGENYLVGRKRDYYGYFKYLYSTFMPADTLLIPGVDKKS
                     VQEIVDSTYEISKRVYDLKKMMLGIDKVSELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
     gene            8972..10843
                     /locus_tag="PC592_002645"
     CDS             8972..10843
                     /locus_tag="PC592_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HDF4056597.1"
                     /translation="MNRKNLSVIMATAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGENLSKLKVITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEAIEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTGTVTSKTIEVGIGDEKVDLTANPIDSTGTNLDPSAEGFRVNKINK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVVNGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKAIELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNVVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGYDRHTTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSSDAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKSALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            10950..11657
                     /locus_tag="PC592_002646"
     CDS             10950..11657
                     /locus_tag="PC592_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF4056598.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGTCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELNKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKRWNPESGHYAIGYHSVK
                     SHFDELATNKIQYVHAP"
     gene            11690..13522
                     /locus_tag="PC592_002647"
     CDS             11690..13522
                     /locus_tag="PC592_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4056599.1"
                     /translation="MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWSKSDTAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENINFERISGNSRYDTSLKLAEKLNKEKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERNLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRNKNDLIDSLAVGV
                     LAAKNSSPIVLAGNKLDTTQKDVLNTKVIDKVTQIGGLGNEDAVKSIIDMQEKTKYTI
                     ETIDELNVAIKKADANDVIIFEPEKDTSISDSFKIETNKAITVEFDGVFKKSITIDMP
                     NGDVKNFGEISDDIRIDNIKKGTLINEGSIQGIDIYSKNGCKIENTSDGDIWIITIDA
                     DAKDVYIENDGDITKISNNAPGVIIKNSGKIDLVNGNEQPAISGKKPTTNDTEYNDER
                     ARGLSVSTKPCSIPEKDRVRVTISSEPKSSRYKIYYRVVEDKPSAMYVGEKISVRSWD
                     LASKSDGSFVEKAKNGSYIEVVEINTSTNKVSRWGRSNVTDDGF"
     gene            complement(13569..13970)
                     /locus_tag="PC592_002648"
     CDS             complement(13569..13970)
                     /locus_tag="PC592_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDF4056600.1"
                     /translation="MILKKHKETILYLFFGAFTTLVNIVSYLFFTRVISFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIELRFLFKEFFSFVSFRLLSGVIEMVIMYIMIDLLF
                     VNDIIVKVFTNIVVIVLNYLFSKMIIFKNKK"
     gene            14198..16609
                     /locus_tag="PC592_002649"
     CDS             14198..16609
                     /locus_tag="PC592_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HDF4056601.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENNKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRSKSRSSLPSSYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATRPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHSVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKSELQRLGTKKVYLIGGEDSLSKNVQAQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKRQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKTVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            16912..18489
                     /locus_tag="PC592_002650"
     CDS             16912..18489
                     /locus_tag="PC592_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HDF4056602.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLVGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERLSGKDRNETNAKVIEKFYSDTSLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLSTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKEDTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKIN
                     KIQDILDKLGFLKKFLS"
BASE COUNT         7774 a         2085 c         3445 g         5393 t
ORIGIN      
        1 atgaagcaga cacctttctt ttataagttc tattttgaac atatttaaaa tgaagtaaaa
       61 aataaatttt taaatttaat aaaataaaat attaatatat agactggata tattaatatc
      121 atatatactc tataatatgt ggaaaataaa gaaaaaataa atggaaaata atcgtaatgt
      181 aaatataaaa tataaaaatc atcaggggga tatgaaaatg aacaaaaaaa tattatcatt
      241 aggtctagca gtatcattaa tcttagtaaa cttcaaaagt gtaaatgcat catcagtagt
      301 agaaaaaata tatggtaaag atagatatga aacagcagca aagatagctg atagacagac
      361 ttatgaaaca gtaattttag taaatacaga aaaatcactt gcagatggat tgagtgcaag
      421 tggattatca ggtgtaacaa aagcgccaat actatttaca caaaaaaata agataccagc
      481 agacacaaat agatgtttaa aaaatatcaa aaaagcatac ataataggta cagaagatac
      541 tataagtaaa tcagtagaaa aggaactaaa ttctaaaaat atagaagtca aaagaattgg
      601 tggagaagat aggctaaaaa caagctattt aatggctaaa gaaatagcaa ctataaagaa
      661 agtggataaa gtactattaa ctaatgcata tagtggagaa gcagacgcaa tgagtgtatc
      721 atcagtagct actagagatg gagctccaat catacttaca gatggaaagg gtatcccttt
      781 tgatgtcaaa aatgttcagt catattgtat aggttcagag gagataatga gtaactcatt
      841 agttaaaaat acaaactcgg taagaataga aggaactgac agatttgaaa ccaataaaaa
      901 tgtaatagac tactttttta agaatgcaga tggattctat gtatcagatg gataccaatt
      961 agtagatgca atagcagctg caccacttac taaagactct ccaatggtgc tagtaaatga
     1021 tggaagtgat aagactgtat tagaaggagc taagaatata acttctgtag gtgaaataga
     1081 tgagaaggta gtacaacaat gtacaaatgc atcaaagtca aatggacaac ctccaacaat
     1141 tacaatagga aatatagaga tatataaggg tgaaaagttt gacactggca aattaaatat
     1201 agtggctaaa gataatactg gaaaggtatt accaatagaa gttgatgggt ttatagatac
     1261 aaatagggta ggtacataca tattgacatt aaaagctaca gatgaatggg gaaaaagtac
     1321 agaaaaaaga gtagaaataa aagtgttgga tgataaatct catgattaca acagcccaga
     1381 atttaaaaaa atggtatcta cagaaatgta taacttaatc aattcctata gaaaagaaaa
     1441 aggcaaagag actttgttag tgtctagtaa gttagaagac atggcaaatg catggtctaa
     1501 gtatatgatg gataaaaaag tatttgcaca ttatatagat ggtaaaaatg ctccacaagt
     1561 attttctgag tttggaatga gaagtgagga aaatatagca tatatttata tagattctaa
     1621 gaaggttcaa acaactcaag atgcaaaaga tttggcaaag gctatatttg aggtgtggaa
     1681 gaagtctcca gagtataatg caaatatgct tagtgatgag ttctatagta ctggatttgg
     1741 gctttatata ttatctgatg gtcaagtgca tgctactcaa gagtttttaa atggcaatga
     1801 aggtagcttg taaaaaattc cataaatgtt gtttttttgt taatttactg atattataaa
     1861 atcaaaatca catctaaagt actttttgta atctgttttg ttattgcttt ataggttatg
     1921 gtattttaga tgttttttgt tttagtagtt tgtaaatttt gagggaatca ctactgggga
     1981 tgtaatttat gattagctga attatataaa aaattagtag gaggagttcg atgaaggtaa
     2041 ataagagaat attatcgata ggattgacaa tatcattaat aatggcagga gcaccaaata
     2101 tcaatgcact ttcaagtata gaaaagatac aagggaaaga tagatatgag acggctgcca
     2161 aaattgcaca gaagcaaacg tatgaaaatg tagtattagt aaatacagat aatacactag
     2221 ctgacggact aagtgcaagt ggattagcag gagcagttaa agcacctata ttattatcac
     2281 aaagaaataa tataccacca gacacagaaa aaatgttaaa agatgtaaag aaggcttata
     2341 taataggaac tgaagattca ataggaaaat cagttgaaaa tgaattaaag caaaaaggga
     2401 tagaagttaa aagaataggt ggtgatgata gaatagaaac aagttatctt atagcaaaag
     2461 agatagcttc aataaagtct ataaataagg tttttataac taatggttat acaggtgaag
     2521 cagatgctat gagtgcgtca tcagtagcat caagagatgg tgcacctata attttaactg
     2581 atggtaaaaa tgttccattt gagaaaaaag aaggtgtgca atgttatgct ctgggttcag
     2641 aggagataat aagtaatgat ttagttaaaa aaactaatgc agttagatta gctggagaag
     2701 atagatttga gactaataaa aaagttataa aacattttta tagttcagca aaagaatttt
     2761 atctttctaa aggttaccaa ttagtagatg cagttgctgg ttcttctata gctaaaaatg
     2821 cacctattgt attggttgat ggaaatagtg ataagtctgt gcttagaagt gctgataaaa
     2881 tcacagcatt aggaggaata gatgaaaaga cactagaaca atgtttaagt gcatcatcac
     2941 tggatgcaag tgcaccaaca ataactgttg gaaatttaaa tatttatcaa ggggataagt
     3001 ttgatataag taaacttaat atattagcaa aggatagcaa tggtaacgat ttgacaccag
     3061 agcttatagg aaatattaat actgataagg ttggtaaata caaagttact ataaaagcta
     3121 ctgatattgg tggaaagact acatcaataa atgtagaagt aaatgtactt gaatataaga
     3181 ctaatgatat gaatagtagt gagtttaaaa gaatggtttc tagtgaaatg tataatttgg
     3241 taaattcata tagaaaagaa aaaggtaaag aaccattaca agtttctaaa aacttagaag
     3301 ggctttctaa ttcctggtct aagtacatgg cagataaagg ccagttttca catgtaatag
     3361 atggtaagaa atctgttgaa gtatttactg gatatgggtt gagaagtgaa gagaatatag
     3421 cttttgtacc acttgttaca aaaagtactt atacgacaaa ggatgctaga gaagtagcaa
     3481 atgtaatatt tacagtttgg aaaaagtcgg ataaatataa tgaaaatatg ctaaatagtg
     3541 attttgtata tactgggttt ggactgtata tattgtctaa tggagaagtg tatgctactc
     3601 aagaattttt aaataagtaa aattaaattt tttaagttat taaatattga aatttaaggg
     3661 tataaaaact catatacttg ggaaaaataa taatttcaaa aaaatgcctt gcaaaaagaa
     3721 ttaaaatgga ttattataga gatgtgagaa atattaggaa tatatggatg attattctat
     3781 gtacataata aagagatgta attttaatat aatgttggga ggaatttaag aaatgaataa
     3841 gaaaaattta gcaatggcta tggctgctgt tacagtagta ggttcggctg caccagtatt
     3901 tgcagcagat gaacaagtta aataccaaaa cacatatact gtagtgcaaa gtaaatatga
     3961 aaaagcttta aaagatatgc aaaaggggat tacagataaa aagataaaat caatagcaat
     4021 atcttatgaa ggtaagccag ttactactat tactgttgca gatatggata caaaaggaaa
     4081 aacttcaaca aaagaagaat tagcaagtgc tttattaaag actactgtta atgataagtt
     4141 agataatttg ggtgatggag attatgtaga ttttgatata acttatgttg gtgatgctga
     4201 tagacttact gcaggggatc ttaatacttt tgcaaaaggt atagcagata gtactgaaaa
     4261 gaaaattcct gctgctaaag gttctaacta tggagttgct aaaacaaatt ctggaactgg
     4321 aaaacttact acagatacag aggcagttat atctacttca atagaaggta aagttgaggg
     4381 aaataatctt acaataagtc ttaaggatgc tccaagtaaa gttggtgtaa taggtgctaa
     4441 taatgataca cttgcagatg ttacatttgc agatgatgca aaattaactg tatcagttgg
     4501 agatccaaaa atagatttag caaaatcatt tatttttgat actaaaactg gtaaattagg
     4561 tggaatagta gaaaaagaaa atgatgcaac tgaacatgca tatgtaagag taataaatgc
     4621 taaagaacaa acaatagatt tagatgctag ttcatataaa tcagctgaag atttagctaa
     4681 agcttatgca tttgatgtaa atgagcttaa gactctttac actgaaatag aagcatatca
     4741 aaaagatagt aataataaaa ctgataaagt tcaaatagtt gatggtaaat atcaaacaat
     4801 actttatgct gaaggaaaga gattaactac taaatcagca actcaagctt ctaaattagc
     4861 agatgaaaac tcaccactta agttagttat aaaagcagat aaattaaaag atttaaagga
     4921 ttatgttgaa gatttaagaa atgctaataa tggttactca aatactgtta ctgtagcagg
     4981 tgatgataga atagaaactg caatagaatt aagtagtaaa tactataata attcagatga
     5041 agacaatgct ataacagaag atgctgttaa taatgttgta ttagttggat ctcaagcaat
     5101 agttgatgga cttgttgcat cacctttagc ttcagagaag aaagctcctt tattattaac
     5161 ttcaaaagat aaattagatt caaatgtaaa atctgaaatt aaaagagtta tgaatttaaa
     5221 aactacaaca ggaataaaca attctaagaa agtttaccta gctggtggag ttaattctat
     5281 atctaaagaa gttgaaaatg aattaaaaga tatgggactt aaagtaacaa gattatcagg
     5341 agatgataga tatgctactt cattagaaat agctgatgaa ataggtttag atgatgataa
     5401 agcattcgta gtaggtggaa caggacttgc agatgctatg agtatagctc cagttgcttc
     5461 tcaattaaat gaaaaaggtg atgctacacc aatagttgta gttgatggaa aagctaaaga
     5521 attaagctca gcagctgaag atttcttaga tgattcacaa gttgatataa taggtggtaa
     5581 aaatagcgtt tctaaagaca tggaagatgc tatagatgat gctacaggaa aatctccaaa
     5641 tagagttagt ggagatgata gacaagaaac taatgcagaa gtattaaaag aatctgatta
     5701 tttcccagat ggtgcagtaa attactttgt tgctaaagat ggatctacaa aagaagacca
     5761 attagttgat gcattagcag cagcaccagt agcagccaac tttggaagaa cttataatat
     5821 aaaagataat gatagttctg gaacagtttc tccagcacca atcatattag caactgattc
     5881 attatcttca gatcaaaatg ttgcaataag taaagcatta ccttctggaa aatcaggaga
     5941 taatttagta caagttggta agggtatagc aaactcagta atcactaaga taaaagactt
     6001 attagatatg tagtataaat ttaaaataca aagtaaaaaa gattcctatt ttaggaatct
     6061 tttttacttt gtattttaaa aaatacctaa ctgattaaga gatgtaattc attcaagtat
     6121 gattattata ctataaataa aaaagttgtc tactattcca catttttaag gtataataat
     6181 agttgtatga taaaaaagga ggtaagaaac acatgtcagt tttagataca atacttgata
     6241 aagcagatga acaagaaatt aagaagttga atttaatagt agataaaata gaggctttgg
     6301 aagaaaaaat acaaaactta tctgatgatg aattgaaaga aatgactaat gtatttagga
     6361 atagattaaa taatggagaa actttagatg acatattaat ggaagctttt gcagttgtaa
     6421 gagaagtatc aaaaagaaaa ttaggaatgc gtcaatatag agtacagtta attggtggga
     6481 tagtaataca tcaaggtaaa atcgctgaga tgaaaacagg tgaaggtaaa acgttagttg
     6541 aagtagcacc agtatatcta aatgctctta caggtaaggg tgtacatgta atcacagtaa
     6601 atgattacct ggcagaacgt gataaagaac ttatgagacc agtttatgaa tctcttggta
     6661 tgacagtagg agtaattata gctaaccaag accaaaatat aagaaaacaa cagtataaat
     6721 gtgatataac ttatggtaca aatagtgaat ttggatttga ttatttaaga gataatatgg
     6781 ttccagattt atctcataag gtacaaagag aactaaactt tgccatagta gatgaggtag
     6841 actcaatatt aatagatgaa gctagaactc cgcttattat tgcaggagat ggagatgaag
     6901 atttaaaact ttatgaattg gcaaatagct ttataaaaac tattaaagaa gaagactttg
     6961 agatggatag aaaagataaa actatagcat taacagcaag tggtataagc aaagctgagt
     7021 cattttttgg tataacaaac cttactgata taaagaatat agaattatat catcacataa
     7081 atcaagcttt aagaggtcat aagcttatgg aaaaagatgt tgactatgtt atctcaaatg
     7141 gagaagtaat gatagttgac gaatttacag gaagagtaat ggatggtaga agatatacag
     7201 atggacttca ccaagctata gaagcaaaag aaggtgttga gataaataat gaatctaaaa
     7261 ctatggctac tgtgacttat caaaatttct tcagactata tgaaaaactt tctggtatga
     7321 ctggtactgc aaagacagaa gaaggggaat ttgagtcaat ctataaacta aatgttgttc
     7381 aaataccaac taataaacca gtgattagag ctgatttaca tgataaggta tttaagacag
     7441 aagaagaaaa gtataatgct gttgtagaag aaataataag gatacataag actagacaac
     7501 caatacttgt aggaacagtt tctgttgaaa aatctgaaaa attatctaga atgcttaaaa
     7561 aacaaggtat taagcatcaa gtcttaaatg caaaacaaca tgataaagag gcggagataa
     7621 tttctaaagc tggtaaatta gatgctataa cgattgctac aaatatggca ggtagaggaa
     7681 cggatatttc tctaggtgca ggagatagag aagaagaaca acaagttaaa aatttaggtg
     7741 ggctttatgt tataggaaca gaaagacacg aatcaagaag aattgataat cagcttagag
     7801 gacgttctgg tcgtcaagga gacccaggta catcaagatt ctttgtaagt cttgaagatg
     7861 atgtaataaa gctttatggt ggaaaaacta tagagaaact tatgaagaga acaagttcaa
     7921 aggaaaatac tgctattgaa agtaaagcac ttacaagagc tatagaaaga gctcaaaaag
     7981 gtgtagaagg taaaaatttt gaaataagaa aaaatgtcct taaatatgat gatactatta
     8041 atgaacaaag aaaagttata tataatgaaa gaaataaagt tttaaataat gaagacattc
     8101 aagaagatat tcaaaaaatg gttaaagata tcatacaaga agcaggagaa aattatttag
     8161 ttggaagaaa aagagattat tatggatatt ttaaatatct atatagtaca tttatgccag
     8221 cagatacact attaatacct ggagtagata aaaaaagtgt tcaagaaata gttgatagta
     8281 cttatgaaat ttcaaaaaga gtttatgatt taaaaaagat gatgcttggt attgataagg
     8341 tttcagagtt ggaaaagaca gtacttttaa aagtagttga ccaatactgg atagaccata
     8401 tagatgctat ggaacagtta agacagtata taggtcttaa atcttatgct caaaaagacc
     8461 cgtttaagga atatgcttta gaaggatatg acatgtttga agctttaaat aaaaatataa
     8521 gggaagcaac agtgcaatac ttatataaat ttaactaaaa aagtgcatat aatttttatt
     8581 aaatgaaaaa taaagtattt tgattcttta tattgtaatt acaattaaat aattaaatat
     8641 ataaatgaaa aagaagctga aaatcagctt ctttttctgt gtgagaaata cggaaaaaag
     8701 agatgcttga aatttctttc ttccatctaa tattatacta taaagaagat gaaaagtcta
     8761 ttagttataa actggattat taaaaaaaat tacagttttg ttactttttt gtatacataa
     8821 atattaaaaa tttaaagtat tagaaaaaat ttatatcttt tggttaatta ttacaataag
     8881 tctcatttat tgaaataata tcaaatatat attataattg gtaaataagg aaaaaatgat
     8941 aaaaaattga attttttagg gggaaaatac catgaataga aaaaatcttt ctgtaattat
     9001 ggctactgca atgataagta catcagtagc tccagttttt gctgcagaaa ctacacaggt
     9061 aaaaaaagaa acaataacta agaaagaagc tacagaacta gtttcaaaag ttagagattt
     9121 aatgtctcaa aagtatacag gaggttctca agttggacaa ccaatatatg aaataaaagt
     9181 tggtgagaat ttatcaaaat taaaagtaat aactaatata gacgaattag agaaattagt
     9241 aaatgctttg ggagaaaata aagaacttat tgtaactata acagataaag ggcatataac
     9301 aaatagtgca aatgaagtag ttgcagaagc aattgaaaaa tatgaaaatt cagcagacct
     9361 ttccgctgaa gctaattcta taacagaaaa agctaaaact gaaactaatg gaatttataa
     9421 agttgcagat gtaaaagctt catatgatag tgctaaagat aagttagtta taactttaag
     9481 agataaaaca ggaacagtaa cttctaaaac tatagaggta ggtattggtg atgaaaaagt
     9541 tgatttaaca gcaaatccaa ttgattcaac tggaacaaac ttagaccctt ctgcagaagg
     9601 atttagagta aataaaatca ataaactagg tgtagcagga gctaaaaata ttgatgatgt
     9661 tcaattagct gaaataacta taaaaaatag tgacctaaat acagtttcac cacaagattt
     9721 atatgatgga tatagattaa ctgttaaagg taatatggta gtaaatggta catcaaagtc
     9781 aattagtgat atttcagcaa aagattcaga aacaggaaaa tataaattta ctattaagta
     9841 tactgatgca tctggaaaag caatagagct tactgtagaa agcactaatg aaaaagattt
     9901 aaaagatgcc aaggctgcat tagaaggtaa ttcaaaggtt aaattgatag ctggagatga
     9961 tagatatgca actgcagtgg ctatagcaaa acaaacaaaa tatactgaca atgtagttat
    10021 agttaattca aataaactag ttgacggatt agcagctaca ccactcgctc aatctaaaaa
    10081 agcacctata ttgttagcat ctgataatga aataccaaaa gtaactttag attatataaa
    10141 agatataatt aagaaaagcc catcagctaa aatatatata gtaggtggag agtcagcagt
    10201 atcaaataca gctaaaaagc aattagaatc agtaactaag aatgttgaaa gactagctgg
    10261 atatgataga catacgactt ctgtagcagt agcaaaagct atggggtctt ttaaagatgc
    10321 atttgtagta ggtgcaaaag gggaggctga tgctatgagt atagctgcta aagctgctga
    10381 acttaaggct cctataatag taaatggctg gaatgatctt tcatcagatg ctatcaaact
    10441 gatggatgga aaagagattg gcatagttgg tggttctaac aatgtatcta gtcaaattga
    10501 aaatcaactt gctgatattg ataaagatag aaaagttcaa agagttgaag gagaaacaag
    10561 acacgatacc aatgctaaag ttatagaaac atattatgga aaattagata aactatatat
    10621 agcaaaagat ggatatggaa ataatggtat gctagtagat gcattggcag caggacctct
    10681 agcagcaggt aaaggtccaa tacttctagc taaaactgat ataacagact cacaaaagag
    10741 tgcacttagt aaaaaattaa atcttggtgc agaagtaact caaataggta atggagttga
    10801 attgacagta atacaaaaga tagctaaaat actaggttgg taataactta tactgtggag
    10861 aagattcctt aataaataca ggaatctttt tctataacta tgctatttat tgtaaattat
    10921 aacattttat gaagtaggag gatgtagtag tggtagatgc aactttattt tttacaccac
    10981 atcaagatga tgaaacttta agtatgggaa gtgctataat tgaacatgtt gaaaaaagtg
    11041 atacacatgt catattatgt acagatggta gtaaatctat aataagaaaa gttttggatg
    11101 atggaggcac atgttcttat catattaaag atgtacataa atattcttta tcagaaagtg
    11161 aattttcaaa agatagagat gaagaattta aggatagttg tgaagcaatg ggtgtaaaag
    11221 aaagtaatat acatatagaa gataatagag cccatgatgg cgagttaaat aaagaaaagg
    11281 caagggaaat aatacttaag tacttagaag aatatccaga tgcaaaagta aaaacggtta
    11341 ctccgtttaa agctagtgga atacatgaag accatagagc attaggagaa gctgcactag
    11401 agttatatag agaaggaaaa ataaaagatt taagatttta tgtagaacca tatgactata
    11461 aggattttaa aaaagttaat ccaaatgtag aggtatggaa ggtattacct agtcaagaag
    11521 agaagttatt aagtgcaatg aatgcatata agagatggaa tcctgaaagt ggacattatg
    11581 ctataggata ccattcagta aaatctcatt ttgatgagtt agctacaaat aaaatacagt
    11641 atgtacatgc tccataaaat attacgaaag aattaggagg taagaattaa tgaaaatatc
    11701 aaaaaagata gtgtctttgt taactatgac atttttaact gttacattat atggaaatac
    11761 atctaatgca tctacaaaag acacattaac aggttctgga agatgggaaa cagcaataaa
    11821 aataagtcaa gctgggtggt caaagtctga tacagctgta ttagtaaatg acaattccat
    11881 agcagatgct ttatcagcta ctccatttgc aaaagcaaaa gatgcaccaa tattattaac
    11941 tcaaagtaat aaattagata gtagaaccaa agcagaatta aaaagacttg gtgtaaaaaa
    12001 tgtatattta ataggaggtt caattgcatt aagttcagag attgaaaagc aattaaatgc
    12061 ggaaaatata aattttgaaa gaatatctgg aaatagtaga tatgatactt ctttaaaact
    12121 agctgaaaag ttaaataagg aaaaatctat ctctaaaata gtagtagtaa atggagaaaa
    12181 gggacttgct gatgcagtaa gtgttggagc tatagctgct caagaaaata tgccaataat
    12241 actttctgat tcagagaatg gaactgaagt agctgataat tttatagata gtaaagatat
    12301 agaaaaatcg tatgtaatag gtggtacata ttctatttct aattctgtag aaagaaattt
    12361 accaaatgca acaagaatag caggcagtag tagaagtgaa acaaatgcaa agattataga
    12421 agaattttat aaagatactg acataaaaaa tatttatgtt acaaaagatg gtacaagaaa
    12481 taagaatgat ttaatagatt ctttagcagt gggtgtatta gcagctaaaa atagttctcc
    12541 aatagtatta gcaggaaata agcttgatac tactcaaaaa gatgtgttaa atactaaggt
    12601 tatagataaa gttactcaaa ttggtggttt agggaatgaa gatgctgtaa aaagcataat
    12661 agatatgcaa gagaagacta aatatactat agaaactatt gatgagttaa atgttgctat
    12721 aaaaaaggca gatgcaaatg atgtaataat atttgaacca gagaaagata ctagtataag
    12781 tgattcattc aagatagaaa caaataaagc tataactgta gaatttgatg gagtatttaa
    12841 aaaatctata actatagaca tgcctaatgg agatgtaaag aattttggag aaatttcaga
    12901 tgacataaga atagataata taaagaaagg tactttgatt aatgaaggta gtatacaagg
    12961 tatagatatt tattctaaga atgggtgtaa gatagaaaat acaagtgatg gagatatatg
    13021 gattataact atagatgctg atgctaaaga tgtatatata gaaaatgatg gagacataac
    13081 aaaaatatca aataatgctc caggtgttat aataaaaaat tcaggaaaga ttgatttagt
    13141 aaatggtaat gagcaacctg caattagtgg aaagaaacca acaactaatg atactgaata
    13201 taatgatgaa agagcgcgtg gattgtctgt tagtacaaag ccttgctcaa tacctgaaaa
    13261 agatcgtgta agagtgacga tatctagtga acctaagagt tcaagatata aaatttatta
    13321 tagagttgta gaagataaac cttctgctat gtatgtagga gaaaaaatta gtgtaagaag
    13381 ttgggactta gcatcaaaat cagatggatc ttttgtagaa aaagctaaaa atggatcata
    13441 tatagaagtt gttgaaataa atacctcaac taataaagtt tctagatggg gaagatcaaa
    13501 tgtaactgat gatggatttt aaatcacctt aaataaagtt aaaaaagtag attactattt
    13561 ctagtagtct actttttatt tttaaaaatt atcatcttac taaacaaata atttaaaact
    13621 ataacaacta tattagtaaa tacttttaca ataatatcat ttacaaaaag taaatcaatc
    13681 attatataca taataaccat ttctataaca ccagaaagta gcctaaaact aacaaaagaa
    13741 aaaaattcct taaacaaaaa tcttagttcg attcttttac tttcaaacac aaaaaactta
    13801 ttagtaacat aagcaaataa aacagcaagt atccatgcca aagcatttgc aaccataaaa
    13861 ttaaatgaaa taactctagt aaaaaataaa tacgaaacta tatttacaag agtagtaaat
    13921 gctccaaaaa ataaatataa tattgtctcc ttatgctttt ttaaaatcaa atataatcct
    13981 cctaagctaa tttaatataa atatacttaa agatactaac aaacattagt atagcacatc
    14041 tatcaataaa tcaatatatc ttaaaatatt ataaaaaata aaactataat attctataat
    14101 taatacgtac tcataatcca tattttatca aaataaaata tgaccttaat ttagaaatct
    14161 gatataataa aaattaaata catataaggg ggtaaacatg agaaagtaca aatcaaaaaa
    14221 attgtcaaag ctactggcat tgttgacagt ttgcttttta atagtgtcaa caatacctgt
    14281 ctcagcagaa aacaataaaa ctctagatgg agtagaaact gcagagtatt ctgaaagcta
    14341 tcttcaatac ctagaagatg tcaaaaatgg agacacagca aaatataatg gagtaatacc
    14401 ttttccacat gaaatggaag gtacaacact tcgaagtaag agtagaagta gtcttccatc
    14461 atcatacaaa tcaagtgtag catacaaccc aatgaatctt ggtcttacta caccagcaaa
    14521 aaatcaagga agtcttaata catgctggtc tttttcaggt atgtcaactt tagaagcata
    14581 tcttaaatta aagggatatg gaacgtatga cttatcagaa gaacatttaa gatggtgggc
    14641 aactggtgga aaatatggat ggaacttaga tgatatgtca ggtagttcaa atgtaacagc
    14701 cataggatat ctgacagcat gggcaggtcc taagttagaa aaagatatac catataatct
    14761 taaatctgag gcgcaaggtg caactagacc ttcaaatatg gatactgcac ctacacaatt
    14821 taatgtaaca gatgttgttc gtcttaataa agataaggaa actgtaaaaa atgctataat
    14881 gcaatatggt tcagtgacat caggttatgc acattattca acatatttta ataaagatga
    14941 aacagcatat aactgtacaa ataagagagc tccattaaat cactctgtag cgatagtagg
    15001 atgggatgat aattattcaa aagataactt tgcatctgat gtaaaaccag aatcaaatgg
    15061 agcatggtta gtaaaaagca gttggggaga gtttaattct atgaaaggat tcttctggat
    15121 ttcttatgaa gataaaactc tactaacaga tacagataac tatgcaatga aatcagtatc
    15181 aaaaccagat agtgataaaa aaatgtacca acttgaatat gctggtctta gcaagataat
    15241 gtcaaataaa gtaacagcag caaatgtatt tgattttagc agagattctg aaaaacttga
    15301 ttctgttatg tttgaaacag actctgtagg agcaaaatat gaagtatatt atgcaccagt
    15361 agtaaatgga gttcctcaaa ataattcaat gacaaaactt gcaagtggaa cagtatcata
    15421 ttctggatac ataaatgtac ctactaattc ttacagctta ccaaaaggta aaggagcaat
    15481 agtagtagtt atagacaaca cagcaaatcc taatagagaa aaatcaactt tagcatatga
    15541 aactaatata gatgcatatt atttatatga agctaaagca aacttaggtg aaagttacat
    15601 acttcaaaac aataaatttg aagatataaa tacatatagt gaattttctc cttgtaactt
    15661 tgttataaaa gctataacaa aaacatcttc tggacaagct acttcaggag aatctttaac
    15721 tggagcagat agatatgaaa cagcagttaa agttagtcaa aaaggatgga cttcttcaca
    15781 aaatgcagta ttagtaaatg gagacgcaat agtggatgct ttaacagcta caccatttac
    15841 agcagcaatc gactctccaa ttcttttaac aggaaaagat aacttagatt caaaaactaa
    15901 gtcagagtta caaagattag gaactaaaaa agtttatcta ataggtggag aagattcttt
    15961 aagtaagaat gtacaagctc aacttagcaa tatgggtata tcagtagaaa gaatttcagg
    16021 tagtgataga tacaagacta gtatatctct agctcaaaag ctaaatagta taaaatctgt
    16081 ttcacaagtt gcagtggcaa atggtgtaaa tggacttgca gatgcaataa gtgttggtgc
    16141 agcagcagct gataacaata tgccaataat acttactaat gaaaagagtg agttgcaagg
    16201 tgctgatgag tttttaaatt catcaaaaat aactaagtct tatataattg gtggcacagc
    16261 tactttatca tcaaatttag aaagtaagct ttcaaatcca acaagacttg caggaagtaa
    16321 tagaaatgaa actaatgcta agataataga taaattctac cctagttcag atttaaaata
    16381 tgcttttgtt gttaaagatg gttcaaagcg tcaaggagat ttgatagatg gactagcagt
    16441 aggagcatta ggtgctaaaa ctgattcacc agtagttcta gttggaaata agttagatga
    16501 aagtcaaaaa actgtactta agtctaagaa aatagaaact cctattagag ttggtggaaa
    16561 tggaaatgaa agtgctttta atgaactaaa tactctttta ggaaaatagt gaatagaaag
    16621 atagtaagga tatacatttt attattaaaa aatattcaat agaagtttat aaatataaaa
    16681 taacaaaaag gggtgtctca aaatgaactt tttagtccat gaggcactct tttttgtatg
    16741 aattcaaata tattttcatc atttcaacaa tggaaaatag gattgtctat attttgagat
    16801 agcctcttta ttattgatga aaaatgtaat aattttaaac tgtaaaatag tgtaaagtta
    16861 ttttataata taaatatagt aagattttaa acaaaataag gaggaataat aatgaaagca
    16921 ccaaaaacta ttttaacaat actgacaata gcgcttactt taagtagcat ttctataata
    16981 ccatcatatg cacttacaga ggaaaaatta gtaggtaatg gtagatatga aactgctgta
    17041 aagataagtc aaaaggcata cagttctagt tctaatgtag tgttagttaa tgataattca
    17101 ttagctgatg cactttcagc tacaccattt gcaaaggcta aaggagcacc aatacttttg
    17161 acagaaagtg ataaactaga tgatagaact gaaaaagaga taaaacgtct aggagctaaa
    17221 gatatttatt taataggagg tactgctgta cttaataaag atatagagaa caaattaaaa
    17281 ggtaatggac ttaatgtaga aagaattaat ggtaaggata gatatgaaac ttcactaatt
    17341 ttggctaata agcttaagga tataaaagat attaaagaag ttgctgtagt aaatggtgaa
    17401 aaaggactga gtgatgctgt tagtgttgga gcaccagcag ctcaaaataa gatgcctata
    17461 attttgtcta gtcctaagga tggagtagaa gcatttgata aatttataag agatgagaaa
    17521 gttataaaag catatgtaat tggagggaca aattcagttt caagagctgt agaaaagagt
    17581 cttcctaatg cagaaagatt aagtggaaaa gatagaaatg agactaatgc taaagttata
    17641 gaaaagtttt attctgatac aagtttaagt aatctatatg taactaagga tggaagcaaa
    17701 aatgaaaatc aactgataga ctcattagca gttggagtgc tggctgcaaa aaatgaatct
    17761 cctgttgttt tggttggcaa taaattaaac acaaaacaaa gggatatact tagtactaaa
    17821 aaattaagta ctataacaca ggtaggtgga aatggaaatg aagaagcttt tgatgagatt
    17881 aaaagtttac aagaaaaaac tgtgtttgaa gcaaaaactg ttgaggaatt aactgatatg
    17941 ataaatatag caagtcctaa tgacattata aattttaaac caaaagaaga tactgtaaat
    18001 gaagctttta gaatggtgac aaataaacca ataactgtga atataaaagg agattgttca
    18061 aaaactctta cagtagatat gcctaatggt gaagtgaata actatgctac tttggtaaat
    18121 gttatagtta gaaatattgg agaaggtgga tttaataatc atgatacaat caccatattg
    18181 tcagttcgtg acaaaaatgg tagagttata gaaaatacta gaaattcaga tatagatacg
    18241 ttgatgatat tagcttctgc taatgataca aaattgatta atgatggata tataggaaag
    18301 cttatagata attcatctaa tagtgatata actaataatg gtactataga taaaaaagtt
    18361 aatcaggttg aggatttaga ggctaaggtt gattcaattg aaaaagctat agattctata
    18421 agtcagaaaa tcaataaaat acaagatata ctagataagc ttggatttct aaagaaattt
    18481 cttagctaaa aatatgtata tttaagtgaa ctgtgtgttg gaattatatc tgaagatata
    18541 tagttaaatg ggtttataga taaataggct tatagctaaa tatatagttc aatatatagt
    18601 taaataaatc ttggggaggt aacatgggga gcggaattga atgtaacaaa agaatacata
    18661 aaagtattga caaaactaga ataaagaaaa ataatct
//
LOCUS       DAMKOJ010000067        18566 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000067 DAMKOJ010000000
VERSION     DAMKOJ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18566
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.072"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            213..1430
                     /locus_tag="PC592_002651"
     CDS             213..1430
                     /locus_tag="PC592_002651"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HDF4056603.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKSYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDRYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKVVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1525..1905
                     /locus_tag="PC592_002652"
     CDS             1525..1905
                     /locus_tag="PC592_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF4056604.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2191..2673
                     /locus_tag="PC592_002653"
     CDS             2191..2673
                     /locus_tag="PC592_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF4056605.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNCINIEKVNDSVFSKRLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVNLQGDGFKNEVSQGD
                     NVKKGSPIISFEREKINSQGIDCTIIMVVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2694..3509
                     /locus_tag="PC592_002654"
     CDS             2694..3509
                     /locus_tag="PC592_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4056606.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKANEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEVIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSINLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNIYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3562..5112
                     /locus_tag="PC592_002655"
     CDS             3562..5112
                     /locus_tag="PC592_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF4056607.1"
                     /translation="MKDKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     FPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQIAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGVDTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEGQSKQLNLDTGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEIY"
     gene            5159..6511
                     /locus_tag="PC592_002656"
     CDS             5159..6511
                     /locus_tag="PC592_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF4056608.1"
                     /translation="MVITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKGYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLENFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6642..7400
                     /locus_tag="PC592_002657"
                     /pseudo
     CDS             6642..7400
                     /locus_tag="PC592_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7447..8166
                     /locus_tag="PC592_002658"
     CDS             7447..8166
                     /locus_tag="PC592_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF4056609.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKKWLELDDFYKIKSIYEFV
                     QNDILFGYNASDILSATQVLNDGMGQCNTKATLLMALLRAVNILCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFSNYGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8290..9690)
                     /locus_tag="PC592_002659"
     CDS             complement(8290..9690)
                     /locus_tag="PC592_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDF4056610.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLVARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLLLSPIAILDVILSFILLKNVGETQKLKLDIPSIILSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPIFIGIISLIFFTLRQLKSREPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPVAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLLHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINSTLRQISGAIGSAVLITIMTSATKKAHMSSAILSNIHGIDVAFSIAATLAFVG
                     LIVSICFIKRHQIIRS"
     gene            complement(9694..10602)
                     /locus_tag="PC592_002660"
     CDS             complement(9694..10602)
                     /locus_tag="PC592_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4056611.1"
                     /translation="MKEGNKVTEKQRLIITIAQKIFDQKGFQNTSISDIVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWENIFSRT
                     TINTYIRENFSEVQRKTTSKLQTKSRANLLNEYKLSLFDNYGDKIENIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFVAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEAYF
                     SLYNKSLFFKTIQDIEELIKTDTSLLENSKLLEATKKLYVEGKNQQYDSLIMDSMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10864..11511
                     /locus_tag="PC592_002661"
     CDS             10864..11511
                     /locus_tag="PC592_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF4056612.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARNAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGNDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKEHITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11836..14475
                     /locus_tag="PC592_002662"
     CDS             11836..14475
                     /locus_tag="PC592_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF4056613.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQTLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGSVVVYGRGSFIVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMVGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEDDFVPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     DGDLALTGKELDALSEEELYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSILFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLRAVAIRGCIIGIVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14533..15636)
                     /locus_tag="PC592_002663"
     CDS             complement(14533..15636)
                     /locus_tag="PC592_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDF4056614.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFLTLDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVNPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQVIDNIE"
     gene            15997..16818
                     /locus_tag="PC592_002664"
     CDS             15997..16818
                     /locus_tag="PC592_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF4056615.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKNGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTTTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIIRDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16898..17108
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17195..18511
                     /gene="argH"
                     /locus_tag="PC592_002665"
     CDS             17195..18511
                     /gene="argH"
                     /locus_tag="PC592_002665"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDF4056616.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCILYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLALDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELYKFSDAFKEDIYDFIDYESILNKGIKKNLK"
BASE COUNT         7108 a         2146 c         3279 g         6033 t
ORIGIN      
        1 gagaatgtaa aaaatatttt taaattatca tttaatgtaa cttaaatgaa ttgaagatat
       61 atgtttattg tattcaattg ttgtattttt aggttttttg tgattaatta aaaaattata
      121 aaaatcgttt acatgttgat ttttaaaaaa aaaagatata gaattatata gaaagtaata
      181 aacaaaaatt ggatttacgg gagtggaatg aaatgatgaa tgttacctta acagatgtga
      241 aagaagctag agagaccatt aagaacatag taaaaagaac tgacttactt gaaagtgtta
      301 aacttagcga aaaaacagga gcaaatgtgt tctataaatg tgagaatctt caaaaaacag
      361 gttctttcaa attaagagga gcttgtaaca aaatagcaag tttgacagat gaagaaaagg
      421 caaatggagt tatagcttcg agtgcaggga atcatgctca aggagttgca ttgggggcaa
      481 aaatgactgg tataaaatct acaatagtaa tgccagcaac tgcaccttta gcaaaagtta
      541 gtgcaactaa aagttatggg gcagaagtag ttttaaatgg tgcggtttat gatgatgcat
      601 atgcaaaagc tgttgaaata caaaaagaaa caggagcaac tttcttacat ccattcaatg
      661 atagatatgt tatagcagga caaggaacta tatctcttga aattttcgaa caattagaca
      721 ataaagttga tactatacta tgcccagttg gtggaggagg aatcatctct ggtgttgctg
      781 ttgcagcaaa agcattaaat cctaatgtaa aagtagttgg tgttcaaact gcaaatatac
      841 cttcaatgaa agagtcaata aaaaatggaa aagtaacaac agcatttaat gatactacaa
      901 tagctgatgg tatagctgtt aagactccag gagatttaac ttttgagata ataaatgaat
      961 tggttgatga aatagtagtg gttgaagaga cagaaattgc agaatcaata ttatttatga
     1021 tggaaagtca aaaaatagtt tcagaaggtg ctggggctgt atgtacagct gctatattaa
     1081 gtggtaagta tgtgccagca aaagatgaaa atgtggtttg tataatatct ggtggtaata
     1141 tagacataaa tactttatat agaataatag gtgttgcttt agctaaagaa ggaagaagat
     1201 attcatttag tacaattatg gaagataagc caggaaactt tgctgagtta actagaataa
     1261 taagtgagaa tggtggaaac attttaagtg ctaatcaagg taaattatca gcaggggaag
     1321 ctctaggaaa acaaagtgcg gaatttatat tagagacaat agattatgac catatagcta
     1381 gaataaagaa agctatagaa gaaaaaggtt ttaaaattat agaattataa taaaaggtgt
     1441 atataatata caagaaaaat agtataatag tgtatgaaga tacattttat atgtattaga
     1501 ttaacgaatt aggaggattt taaaatgaaa catgaagtaa tacatactaa tgatgcacca
     1561 gcagctttag gaccatactc tcaagctata aaagctggaa acttattatt tgtatctgga
     1621 caagttcctc ttgtaccaga gactatggaa gtagttgaag gagatgtaca agctcaaact
     1681 gctcaatctt taaaaaatct taaagctata ttagctgaaa gtggagctga tttttcaaat
     1741 gtagttaaaa ctacagtatt tataaaagat atgaatgaat ttggagctat aaacgaagtt
     1801 tatgctgaat attttggaga aaataaacca gcaagagctt gtgtagaagt tgctagatta
     1861 ccaaaagacg ttaaagttga aatagaagta atagctgtat tataaaaata caatattttt
     1921 aatttgaaaa ggctgaagaa ctatattcta gtgattcagc ctttttataa aaaataaatc
     1981 aaaagcttaa agagcttgat aaatattgtc gaattaaaaa ataaaattaa aataaatatt
     2041 gcaatatttt tgagaaggtt ttataatgag tatataattt gaaacgtgta actattaaat
     2101 taggcatgag ttcttggata tttttatcct gaggattcat gccttttttg tattgaaaat
     2161 caaaaatcta tttaataagg aggaagtact gtgttaaatt ttttcaagaa aaataaaagc
     2221 tataagttac atgcagtagt gagtggtaac tgtattaata ttgaaaaagt aaacgattct
     2281 gtgttttcaa aaaggttaat gggagatgga gttgcaatta ttcctaatag taatgttgtt
     2341 gtagctcctt gtaatggtaa agtaactgtg cttacagagt caaagcatgc atttggtatg
     2401 gtctcagatg agggtgttga aatattagtc cacataggaa ttgatacagt taatttacaa
     2461 ggtgatgggt ttaaaaatga agtgtctcaa ggagataatg ttaaaaaagg tagtccaata
     2521 ataagctttg aaagagaaaa aataaattct cagggaattg attgtacaat aataatggtt
     2581 gtattaaatc atagcgaatt ttcagaaata aattgcatgg tagaaaatga agttgttgca
     2641 gggcaagata ctgttattga aattatgaaa tgataggaag ggattaattc aatatgagag
     2701 tagtaaaaat ctttaataat aatgcattat ctacagtaac taatgatagg aaagaagcta
     2761 ttttactagg tcttggtata ggttttaata aacgtccagg agataaagct aatgaagata
     2821 aaatagaaaa gatttattat gttcaagacc acatgcaaac aaaattttta gaattgttaa
     2881 aaaatgttag tccagaagtg atggatgctt cacaacaaat tataagtctt ataccaggga
     2941 atgagggaaa atttaataat aaagggatat tatctttagt ggaacatatt agttttgcaa
     3001 tagatagaat gaaaaataat gtttttctac ctaatttaat gcttttggat ataaagatga
     3061 tgtattcaaa agagtttgag ttaggagtaa aagctttaga agttatatac agagtatgtc
     3121 atatccattt gcctgaagat gaagcaggtt acatagcttt acattttgtc aatttacaat
     3181 caaatgataa tttggcatat gatactttaa aatttgtaaa aggtagtatt aatttgatta
     3241 aagaatgtta tggattagaa ttagacgaat cgagtttgag tacattacgt tttaggactc
     3301 atcttaaatt tcttgctcaa agaattttta agaatgaaat ttgtcaggat gataaaatga
     3361 ttgaaatgta tgattattta attaacaatc atcctaaaaa taaagaatat ttagaaaagt
     3421 taaatatata tattgaaaag gagtttaggt ataaattaga taaacctgaa aaaatttatc
     3481 tactgctaca cttaacaaaa atcttataag aatgagatga attagtaata gaaatatata
     3541 taattttaag gggggataag attgaaagat aaactacttg gaggactgga aacatttgca
     3601 aaggcaatgg ttcagccatt aatgtattta tcaagtgcag ggatattaat ggtggtaggt
     3661 gtactactta caaatgatat gttactagga gtatttccat tttttaaatg ggagccaatt
     3721 caaatatttg gaagcctaat ttataactgt ataatggcta ttattaataa tcttgctgtt
     3781 atatttgcta taggtattcc tgctgcacta gcaaaaaaag agaaacacaa agcagcatta
     3841 ataggattta tgagttatat aatatacctt acagcttcta acactatgtt aacatcacta
     3901 ggtcaaatag caaaagaaag caagatgctt gggttgatag ggactggaca agctactatt
     3961 ttaggtattc aagttgtaga tacaagtgta tttggtggaa ttattttagg gtgtatagct
     4021 ggatatgtat ttaatcgtac aagtaacaaa acatttaaag gagctttaca gatatactca
     4081 ggagcaaatt ttagttttat atgtatgttc tttgtatcca ttttaattgg cgttgtgagt
     4141 aactttatat ggccattagc tcaacaagga atagcttctc ttgcaaatgt catcaaagat
     4201 acaggtacat ttggtttatt cttatatggt tttttagaga gaatattagt accaactgga
     4261 cttcatcatt taatctacac accatttcag ttttctgatt taggaggagt gcttaaagtt
     4321 ggtgtagata cagtttcagg agcttatgct atagttatga cagaaatgaa tttaccagtt
     4381 gagcgtttct cagatagtat atactacatg gcaactggat ttacaaagat gtttggttat
     4441 ataggtatag gagctgcctt tatttatact gcatataagc aaaataagaa gaaggttaag
     4501 gcaacgatta ttccactaat aattacggca gtattagcct ctgtaacaga accattagac
     4561 tttatgtttg tattctgtgc accactttta ttctttgtac atgcagttat agctggtcta
     4621 tttatagctt tattaaaaat atttgatgtt actgccttat gtggagggaa cttattagta
     4681 tcaattataa tgaatactac agtaggtgta gaaaaaacac actggccagt aatgatgata
     4741 ttaggacttg cacaaattat tgtatatttt gtagtattta gttttttaat taagaaattt
     4801 aattataaaa ctccaggtcg tgaagatgag agtacagcta caggcgaagg acaatcaaaa
     4861 caacttaatt tagatacagg tatagaaaat ataattgatg ggttaggtgg aaaggaaaat
     4921 attaatacag tagaaaattg catcactaga ttacgtgtta atgtaaaaga tgaaagtaag
     4981 attaatgaag atataattaa tttaacgcca aatagcggga ttgtaaggaa aggaaaagat
     5041 atacaaataa tttttggact tcatgtgcat gaggtaagac gtgcagtaga agatttttta
     5101 gaaatttatt aaagatacat ataatttata tagagtttat agaggaggaa taattattat
     5161 ggttattact attgttggag gaggaagcac atttactcca ggtattgtta agtcaattgc
     5221 attaagagaa aaagagttag agcttgaaga aattcgttta tttgatattg ataaagaacg
     5281 tcaagataaa gtagctgtag ttgtcaactg gatactaaaa gaagatgtta aaacagatgt
     5341 taaactaact gtaactaatt gtgaaaaaga agcttataca gatgctacat ttatatttgc
     5401 acaaatgcgt gttggtaaat atgaaatgcg tgagcaagat gaaaaaattc cattgaaata
     5461 tggttgtgta ggtcaagaaa cttgtggttg tggagggatg gcatacggat tgcgtacaat
     5521 acaaccaatg ataaaggtta ttgatgatgt agagaaatat gctaaaaaag gttattggat
     5581 attaaattac tctaatcctg ctgcaatcgt ttctgaagct tgtcgtaagt taagaccaaa
     5641 tgcaaggatt ataaatatct gtgatatgcc aatagctatt atagatatga tagcggggtc
     5701 attaaatatc aatgacgtcc ataatatacg ctatgattat tttggtctaa atcattttgg
     5761 ctggtttact tcaatagatt ataaacatag agacttaatg gaagagatta aggaatacat
     5821 aaaagaaaat aaaatattac taccaaaatc ttatatagaa aacttaaata aaagtcgtag
     5881 tacaggaaat cgtcatgctg taagtagctg gatacatgtt tgggaatctg tttatacaat
     5941 gttagaaaac ttcccaaaat atctaccaaa cacttattta acatactatc ttttaagtaa
     6001 agaaacagtg gaacattcaa acataaatcg tactcgtgca aatgaggtta tggaaagccg
     6061 tgaaaaagac ttatttgaag gtgtgagaca ttacttagaa actggagaaa tttctgaaaa
     6121 agcattttat gcaggctcac atggagattg gattagtgat ttggcagttt caattaaaaa
     6181 tgatacacgt agtcgttttt tagttataac tgaaaatcgt ggagctatcc caaacatgcc
     6241 atatgatgca atggtagaaa ttccagcata tattggtaaa gatggtccag aagttattgc
     6301 tcgaggtcca atacctctat tccaacaagg attaatgatg caacaactta acagtgaaaa
     6361 attgatagta gaagcttata tagaaaatag ttatgaaaaa gctttacaag cattcacatt
     6421 aaataaaact attccaagta tgaatgttgc taaagaaatt ttggatgaaa tgatagaagt
     6481 taataaggaa tactggccag agctaagata gtaggataga agaaaaggtt tttatttaat
     6541 aattaggtat gttttcagag tcttttatca aaatgtattc acaaacatat ggcaatatat
     6601 taaagtaaag agtgatattt ttagaagaat ggggtgatgc aatgaacatt ataaataaaa
     6661 ttttttggca agaagatagg attggcatga ttacaaataa tttagaggca gatacacata
     6721 gtcactgcat gttacaaatg ttcttaggga tagaagaaaa cattgaaata atagtcaatg
     6781 aaaaattagt taaatgtaat tgtatcgtag tagataaaaa tatctctcac tcattttcag
     6841 caagaaaaaa agtttattac tctgctatta ttgaacctac atctatatat gcagaacagc
     6901 ttacctcaaa aatgagtgat tttggctact ggatatgtga caatgatgga ttagagaaat
     6961 tacgtcaaca aggaactttt ttgatatata attctagtaa agaacaatat ttaagattta
     7021 tggaaatgct taataactat ttgaatatac ctataactct caaaaattat gatgacagaa
     7081 ttactgaatt gctcaattta ttacgtactt gcaattgtga taatcatact atttcaagtt
     7141 ttgcagataa agtgtcccta tcagcaagta ggctatcaca tctgtttaaa taacaaatag
     7201 ggataccttt aaaaagctat atcttatttc atcaaatgga gtgtgctttt agagaattac
     7261 tttctggaaa aaatgttacc gaaacttcta tgactgctgg attcgatact ccatcacact
     7321 ttgcagggac agttaagcga atgatgggaa tgcccgtttc tttatctttg aaagatagcg
     7381 agtttttgaa agtatattga atattctcgt tatataatga agttgtatta agaaaggggc
     7441 tttattatga ataaagaata tttagaagaa acaaaaatgt taaattataa tgaaccacaa
     7501 cttaagctct tggtatcatc aaagaagtgg ttggaattag atgattttta taaaataaaa
     7561 tctatttatg agtttgtaca gaatgatatt ttatttggat ataatgcttc tgatatatta
     7621 agcgcaacac aggtattaaa tgatggtatg ggacaatgca atacaaaagc tactctttta
     7681 atggcattat tacgtgcagt gaatatcctt tgtaggcttc atgcttttga tgtaacaaaa
     7741 gattttcaac gaggtgctac atccaaattg atttcactat tagcaccaaa atatattctt
     7801 catacttggg tagaggtatt ttatcaagat aggtggattg ctctggaggg tgtcataact
     7861 gataaaaaat atttagaagc aattcagaag aaattttcta attatggtgg aacgtttaaa
     7921 aagtatgcaa tagctacaaa tgatttgaaa aatacatcta ttgattggga tggtaaagat
     7981 acttttatcc aaaaagaagc tatcgtgtat gattatggta tttttccatc accagatgta
     8041 tttttttcta ctcattcaca acatatgtca aaattaaaga atttcatata tgtacatctt
     8101 atcagaaaaa taatgacaaa aaatgtatgt aaggctagaa ataattatat tgataaaaac
     8161 gaatgagtgt ttaagaagtg actatatagg aaatatatag aacaattaaa actgtattgg
     8221 ttaaaatgaa taaaaaggag ttatcaaaga gcaaacttaa attgttcata ggataactcc
     8281 ttttttatat taacttctaa taatttggtg tctttttata aaacatatag atacaattaa
     8341 accaacaaat gcaagagtag ctgctattga aaatgcaaca tctattccat ggatattaga
     8401 cagtatagca gaactcatgt gagctttttt agtagcactt gtcattatag taataagcac
     8461 agcagaacct atagcaccag atatctgacg aagtgtacta ttaatcgctg tggcatgaga
     8521 tatgagttct ctgtctagtg ttttaattcc ccatgtagtt aatggcatca aaaccattga
     8581 gataccaatc atacgaatac aatacatcaa tgatacatga agtaaagatg tatccctacc
     8641 taaaaaagca aaagatagag ttcctaaaaa taaacatcca gttcctaata tcgatagagc
     8701 atgaggacca tatttatcta aatgacgtcc tgcaactgga tttaatacaa ccattaatat
     8761 agcgccaggt aacattaatg aacccgaaga caatgcagaa aatcctctta cagactgaac
     8821 atatagagga atcattaatg tagcagacat cattgaagca tatacaatca taattaatat
     8881 tgtagaaatg agaaatggtt tatttttaaa aaccctcaat tctaaaaatg gttctctaga
     8941 ttttaattga cgtagtgtaa agaaaattaa tgatataatt cctatgaata ttggtaaata
     9001 tgtggcaata ttagtccacc cataattacc ttgattagta aatccaatta acaaaccacc
     9061 aaaacctaga gatgacagta ttattgaagg aatatctaat tttagttttt gcgtttctcc
     9121 aacatttttt agtagaataa atgaaagtat aacatctagt atagctatag gagaaagaag
     9181 caaaaataaa ctatgccagc caaatgaatc tactaaccat cctgataaag ttggtcctat
     9241 tgctggagca aatcctactg taataccaac taaactcata gctgcaccac gtttttcctc
     9301 agggcataaa tatagtataa taacttgtaa aagtggcatt agagaaccag aacccattgc
     9361 ctgcaacaca cgagcaacca acatagttga aaaattatta gaaaaaagtg caataataca
     9421 tcctatagaa aatatagaca ttgatgtaat gaataacttt ctagtactaa atctatttat
     9481 caaataggct gttgtgggca caataatacc tgcaataagt agatatattg tcgttaacca
     9541 ctgaccaaca tcagcagtaa ttttaaaatc tgacattata ttaggtaatg ctgtagataa
     9601 tagtgtttga ctaagagaac ttataaaagc accagtcatt acgattgcta ttattaaatt
     9661 tcctttttta ttgttacttt gggtttccat aatttacaac gtctcctttt ttaattgatt
     9721 tttaatgctg ttcaataaaa gtacctttgg tctcaaagtg tcttcttttt ccaaatatgc
     9781 aatcattgaa tccataatta aagaatcata ttgttgattt tttccctcga catataattt
     9841 ttttgttgct tctagtaatt tagaattttc aaggagagaa gtatctgttt tgattagttc
     9901 ttctatatct tgtatcgttt taaaaaatag cgatttatta taaagggaaa agtaagcttc
     9961 atcttcttgt ttatgtaaaa acattgattt ttcaattaaa ggatttagat tatccatatt
    10021 ttctacaact aaatctagaa tttgtatagt aaatttagca acaaagtata catttatttc
    10081 tcttttctgt acatgaataa tgtatataaa ctgatgaatt agagcatcca ataagaaaac
    10141 taaatcaaat atgatgtttt ctattttatc accatagtta tcaaataagc ttagcttgta
    10201 ttcattcaat aagttagctc ttgattttgt ttgcaattta cttgtagtct tacgttgcac
    10261 ttcagaaaaa ttttctctta tgtaggtatt tatggtagtt ctagaaaaaa tattttccca
    10321 tacagcaatt atctttctgt ttaacttttc agatgatgga atatcattat tttcattgat
    10381 agaatgtata atttctaaaa acttttcatc ataataattg attatttcgc agataaaact
    10441 ttccttagtt tcaaaatgct tgtaaaaagt agctttagac attttgcact cttttacaat
    10501 gtccgagatt gaagtatttt gaaaaccttt ttggtcaaaa attttttgtg caatagttat
    10561 aattagcctt tgtttttctg tcactttatt accttctttc atataaaaaa cgtttagtac
    10621 tatatagtac ctataagttt taataaatat attatacatc atttggaaaa aaaatcaata
    10681 tatacactgt aatatgaaat ttttgaaaaa tttattgtta tttttagtcg tataaaaaag
    10741 aaacttaaga gtttcttaag aattgtttaa ataaattgca ataaattagt ggtatgatta
    10801 tagtatgaaa gagaatgtct tgaaattttt ctgtatcaaa ttccaattat ggaggtgtag
    10861 tatatgaaaa agaaaatttg tgtagccata atttttgctc tatttatagt ttttgtagaa
    10921 atgtttattg atagttctag tgaaggaagt aaaattatga cagctgaatt aagtaaatac
    10981 aggaagggcg taaatgtatt atcaataaac aatattatag tagcgaataa aaaatatagt
    11041 ttacctaaag actattctcc tcaggaaagt agtgaagcga gaaatgcttt ttataaaatg
    11101 aataaagatg ctcaaaaatc aggattaaat ttaaaagctt ttagtacata tagaagttat
    11161 gaataccaag atagattatt taagtcatat gtaaaagaac atggagaaaa agaagcaaat
    11221 agattttcag ctaaacctgg agaaagtgag catcaaactg gacttgcttt tgatattggg
    11281 gggaatgacc agtcttgttg ggcaaataaa aagtttaaca atacaaaaga agctaaatgg
    11341 ttgtatgaaa atgcatataa atatggtttt atacttagat atccagaagg caaagagcat
    11401 ataacaggat atatgtatga atcttggcac tatagatatg ttggaactga acatagcaaa
    11461 aactttgcaa tgaataactt gactctagaa gaatatttac atataaatta agagatagtt
    11521 tgttaaaatt aggttaaaat aaaaaataaa ctagactatt aattgtgtaa agtgatataa
    11581 tgtaaatata atttaagata actactcgaa ggggagtagc ttacacgaaa gtggtaatta
    11641 atcgtcaaga cagtagaaat actcggttaa ttagcaaggg attccttgat agcaagacct
    11701 tcaaaataag cattaggtat gtttgttttg gggtcttttt ttattcaagg aatttttatt
    11761 taaaaaaatt taaatttcaa gtatacataa gagcccccaa acataaaata aatttattga
    11821 agaggagggc aacaaatgtc ttacaaaagt acttatcaag aagtaattaa aaatttagac
    11881 tcaagtttat ctggtttgag taaagaaaga gcagaagagt tgttagaaaa aaatggagct
    11941 aatgaattaa aagaagcaga taaggttcct acttataagc ttttcctaga aagttttaaa
    12001 gacccattag taataattct attgatagct gctttagtac aaatattttt aggtgaaaca
    12061 gtggagtcta taataatttt tgcagttatt attataaact ctgttctggg tgttgtacaa
    12121 acaaaaaaag cagaaagttc attagaaagt ttgaaaaatt tatctgcacc aaacgcaaag
    12181 gtaataagag acaataaaaa aatgacaatt ccagcaaaaa atctagtagt tggagatatt
    12241 gtattcttag aagctggcga ttacatacca gcagatggaa gacttataga agcacaaact
    12301 ctcaaggttg tagaaggtat gctaactgga gaatcagaac cagttttaaa gcatacagaa
    12361 aaaataagtg aagatgtaag tttaggtgac cagaaaaata tggtatttag tggctctgta
    12421 gttgtttatg gtagaggttc ttttatagtg accggaacag gtatggatac agaaatgggt
    12481 aaaatagctg ggcttttaga aagtgctgaa aataaactta caccattaca acaaaaaata
    12541 gaggatttta gtaaaaaact tggtgtaggc attgtaatac ttgctctttt aatatttata
    12601 attcaagtag caagaaatta ctttatggtt ggaaatggag aaatgacaca aattatttta
    12661 gattcattca tgttctctgt agcagtagca gtggcagcta taccagaagc tttatcgtca
    12721 atagtcacta tagtattggc tgttggaaca aatagtatgg caaaaaaaca agccataata
    12781 agaaaattac cagcagtaga aactttaggt tcaacaagtg taatatgtac tgataaaaca
    12841 ggtactctta cacaaaataa aatgacagta gttgattatt atatgtatgg aactaataat
    12901 gatgagttag ataaagaaaa agtaaactat tcttatcatg ctaaattatt gactatggtt
    12961 tctacattgt gtaatgactc tcatataact agtgatggta aagaagttgg cgacccaaca
    13021 gaagtagctt taataaatta ctcaagtaaa aatgatttag attatgataa attaagaagt
    13081 aagtatatta gaataaatga aataccattt gactcagata gaaagcttat gtctactgta
    13141 aatagtatat atggagacta tataatgttt acaaaaggtg ctccagatat tgtgtttagt
    13201 agatgtaaat atgctttgaa aaatggttca aaagtagata taacagatga gataatagaa
    13261 gaatataaac ataaaaatga agagttttca aatagagcac ttagagtatt agcttttgca
    13321 ataaaagatg ttccagaaga tgattttgta ccttcaattg atgatgaaca tgacatgaca
    13381 ttggttggaa taatggcaat gatagaccca ccaagagaag aagtaatgga tgcagtaaaa
    13441 gaggcaaaga gtgctggtat aaaaactgtt atgataactg gtgaccataa aacaacagca
    13501 gcagcaattg caaaagagat tggtataatg gaagatggag acctagctct tactggaaaa
    13561 gagcttgatg ctttgagtga agaagagcta tatgaaaaac tagaaaatat aagtgtatat
    13621 gccagagtct caccagaaaa taaaattcgt atagtaaaag catggcaaca taaaaataat
    13681 ataacagcaa tgactggtga tggtgttaat gatgcacctg ccttgaaaca agctgatata
    13741 ggaatcggta tgggaagtgg tactgatgta gcaaaagatg cttctgccat ggtattggtt
    13801 gatgataact ttgcaagtat agtaaatgct gttgaagttg gtagaacagt atacagtaat
    13861 ataataaaat caattactta tctatttgca ggaaacttag gagctatagt atccatatta
    13921 tttgcagtat ttgctggttg gtcaaatcca tttacagctt tacaactttt atttataaac
    13981 ttagtaaatg actctttacc agcaattgca ttagggtttg aaaagtcaga aaaaaatata
    14041 atgaataaac ctcctagaca tccggatgaa agtatactag caggaggaac attgagggca
    14101 gttgctataa gaggttgtat aataggtata gttacaataa ttgcacaata tataggattg
    14161 caagtatctc cagaacttgg agtagcaatg gcattttcaa cattgatatt agctagaata
    14221 atgcaaacat tacctgcacg ttctaataat caaacagtaa taaagttagg tttttttagt
    14281 aataaatacg ttataggagc agttctagtc tgtcttgggc tttattcttt aacactaata
    14341 ccagtgctaa gaggaatatt ctctatacca acaacatttg gattgtatca gttgggaatt
    14401 tgcttaggtt tagcattgat ttcatcaata ttaatggaac ttaacaaatt aataaacaga
    14461 agtgaagtaa aataaataaa aaattaaagg gcatattgat tttaacaata tgccttttat
    14521 aaatagtcta acttattcta tattatcaat tacttggaat gcctttataa cttcaggtaa
    14581 ttctttttct tcaggcattc taaatcttat gaaattttta tcaagtccag taaaatcact
    14641 tccagatata actcttattt ttaatttagc aaactcttgt tgcaaatcta tgtccttgtt
    14701 cttatgttca actgtcataa ttgatacagt atcactagtt tcagctatat taaggttttt
    14761 ccatggaatt aataattgat tttttatatc ttttgttttt tcttttaatt cttctataaa
    14821 ttggacatca tctaataaat tggctgcaat actacgagat atttcagata cttcgtaagg
    14881 agtagaaatc tttttaatag ggttaacaag ttgttctgga agaactgcat atcctgctct
    14941 tagtcctgct aaaccaaaac cttttgaaaa tgtttttaaa gcaattacat tatcataatt
    15001 atttaaaagc ttaacagctg aattttcttt tggcatgtat tcaccataag cttcatctac
    15061 cataactgct atatcatatt tagctgcttc ctttactata ttttcaattg atgataaagg
    15121 tataatttgt cctgtaggat tatttggatt gtctatataa attactttat attctggatt
    15181 tattttttca ataaattctt tttcattaaa cttgaaatta tcctctttct ttaaaagaac
    15241 atagtcataa gtagcaccat gcatttttat atctgtttca tattctgaaa actgaggtga
    15301 atatcctaaa actttatctc ccttttcaat aaataatcta tttaaaaggt aaataacatg
    15361 tatagaacca tctgccaaac aaattctgtc agtgtctaat gttaagaagt ctttccaata
    15421 atcgactata ttgtctttta aagcaattga atgaggatat cctcttatca tatcaaattt
    15481 taaagcatta aaagcttcta cagctttgtt tgagtaagat actgtattta taccttcacc
    15541 acagtctatc tcgaatacat cttctgaatg tccagattct attgcataac tttttttcaa
    15601 ctgcatttca atagctttgt taatttttaa tttcatagtt tatcactcct tatttagtca
    15661 ataataaatg ttataaaagt tgctagattt aaaatattat gaaaatatat aatagtaaaa
    15721 aatgaatata aatattataa tagctcactt tatttaatat gattatatat catatattgt
    15781 aaaatttcta gcattataag actataaatt gaaaatattc agaaaaatac tacaagaaac
    15841 gatttatttt gctcttaaaa taagttaaat gaatgttatt aattttgtaa attgaaatag
    15901 tttaagtata aagttatgat ataatctaat aagggtaatt ctttagatta tattaaggaa
    15961 atataagtat acaataaaaa gttatggagt tggattatgg gatataaatt aattgtaaca
    16021 gatatggatg gaactttatt aggaaataat cataaagtta cagatgaaaa taaaactgca
    16081 ctacaaaaag ttataaaaaa cggtattaat gtaactttag caacaggaag agccttcgat
    16141 tcagctaaat gcaatgtaga ttttcttaaa gaggacatgc caataatagc ttgtaatggt
    16201 tcattgataa gagagcaaaa cggaaacata atatattcaa ataagattga tacaacaact
    16261 tgtttaaata tcttagatgt attagataaa tacgatattt attatcaatg taatagtata
    16321 gattctatgc tttcaaaaaa aatagaagga cgagaagata gattaagtgt atttttaggc
    16381 tctgagacag aagtaattat aagagatgat ttgagagaag aaatttttaa aaaagatata
    16441 ctaaaatttg taatcataga agaaaagaat ccatctattt tggatgaaat aagaaaagaa
    16501 ttgagaaaag ttcaaggaat aaagataacc tcttcatggc caaacaatat tgaagtcatg
    16561 aatgaaggtg ttgataaagg taatgcagtt aaaattttag ctgaaaaaat gaatatagat
    16621 agagaagata taattgcatt tggagataat tacaatgaca tagaaatgat aaaatttgct
    16681 ggtcttggag tagctatggg aaatgcagaa gaattgatta aacaagaagc tgattatgtt
    16741 acagatacaa atcaagacag tggagttgca aaggcaattt ataaattcct agagttaaaa
    16801 gaatcactta gttcttaaaa tgatatataa ttaggaaaaa ataggttgac tattttgtag
    16861 atagtaatta taatacaaat agataaaaca taaaaattta gattcagtga aaaagagagt
    16921 agatatggag aaaatctcag cgaattgggg atggtgtgag cctaatgata acactttata
    16981 ttgaaaagaa ctttggagaa tactacttga aattcagtat ggtagtaggt aatctcgcct
    17041 taagagaata gagtgggtaa acattgtttg ccaactagag tggtaacacg gaatatttcg
    17101 tctcttggtc tttttgacca agagattttt tagtttcatt aagctataag aattataatt
    17161 aaaatacaaa aaaataaaat atgaggtgaa agttatgaaa ttatggggcg gacgctttag
    17221 aaaagcagaa aatcaactta tggaagaatt taataaatct tttggctatg attgtatact
    17281 gtacaaaaaa gatatcgaag gaagtgtagc acatgttcat atgcaagtaa aatgtggact
    17341 tttaacagaa gaagaaggaa agtctataac agaaggatta aaagggatac ttgaagatgt
    17401 agaaaatgga aagttagcat tagatggaga gtatgaagac atacatagtt ttactgagat
    17461 aaatttaatt caaagaatag gagatgttgg aaagaagctt catacagcac gtagtagaaa
    17521 tgaccaagtt gcagttgata tgagattgta tgccaaagaa aaagcaaatg atttggtaga
    17581 tttaatatct gaatttaaag cgactataaa agatgttgct gataaaaacc cggtgatgat
    17641 gccaggttat actcatcttc aaagagcaca agtagtgaca tttaagcatc acttaatggc
    17701 atattacagt atgtttgata gagatgagaa aagaataaaa aatgctatag aaatattaga
    17761 tgaatctcct ttaggttgtg gggctttagc aggaactaca catgatatag acagaagtat
    17821 aacttgtgaa caattaggct ttaaaaaagt agtagataat tttatggatg gagtaagtga
    17881 tagagattat ttattagaac taatgagtga cttttcaatt ataatgatgc acttaagtag
    17941 attaagtgaa gagttaatac tttggagttc acaagaattt ggatttgttg agatagatga
    18001 tttatataca actggaagta gtataatgcc tcagaagaaa aatccagatg gtgcagagct
    18061 tataagaggt aagactggca gagtatatgg aaatttattt ggtcttttta cagtaatgaa
    18121 aggaatacca ttagcatata ataaagacat gcaagaagat aaagaaggtt tcttcgatag
    18181 tgtacatact cttgaaatgt gtatacaaat aatggataga atgatagcta cactaaaggt
    18241 aaatgaggat aaaatgaaac aagcagtaaa gaatggtttt ttaaatgcaa ccgaagttgc
    18301 agattattta gttaaaaata atgttgcttt tagagatgca catggtatag taggaagtat
    18361 cgttatatat tgtgaagata ataaaaaagc aatagaagat ttaacattag aagaattata
    18421 taagttttca gatgctttta aggaagatat ttatgatttt atagactatg agagtatatt
    18481 aaataaggga ataaaaaaga atttaaaata atatacttat ttctaaaagc tgtagatttg
    18541 aatgttatca ttcaaatcta cagctt
//
LOCUS       DAMKOJ010000068        17989 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.074, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000068 DAMKOJ010000000
VERSION     DAMKOJ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17989
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.074"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            174..395
                     /locus_tag="PC592_002666"
     CDS             174..395
                     /locus_tag="PC592_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF4056617.1"
                     /translation="MGYLKEDRQDYCCEFARPYVNRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            395..658
                     /locus_tag="PC592_002667"
     CDS             395..658
                     /locus_tag="PC592_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF4056618.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESRYGALTNFGYESSEHPWSWISEPWPWDKSFYK"
     gene            722..1294
                     /locus_tag="PC592_002668"
     CDS             722..1294
                     /locus_tag="PC592_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF4056619.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGSCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            2086..2739
                     /locus_tag="PC592_002669"
     CDS             2086..2739
                     /locus_tag="PC592_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2 family
                     protein"
                     /protein_id="HDF4056620.1"
                     /translation="MNFIYSNAEIEYLKHKDKILSDIIDKIGHIEREIDTDLFSSVIH
                     HIIGQQISTKAQATIWKRMKEHLKEINASSILSAGTTGLQSFGMTYRKAEYLTDFATK
                     IQNGEFDLQSITYMSDKEAIDKLTSLKGIGVWTAEMILLFCLQRPNIFSFDDLAIQRG
                     LRMVYHHRKITRKMFEKYQKRFSPYCSVASLYLWAVAGGVIDGMRDYAPKGKVRKNG"
     gene            2901..3434
                     /locus_tag="PC592_002670"
     CDS             2901..3434
                     /locus_tag="PC592_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF4056621.1"
                     /translation="MQYINYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGEEPNFTPSLHMVGTPFQTAVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNRSLTGYAGGIDRKIKLLSL
                     EKVSMQHYFIPKKGSAL"
     gene            complement(3988..4773)
                     /locus_tag="PC592_002671"
     CDS             complement(3988..4773)
                     /locus_tag="PC592_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDF4056622.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQGNIGDMQGSI
                     SGIEGTISGMQGTISDMQGNIGDMQGSISGIEGTISDMQGNIGDMQGSISGIEGTISS
                     VQGTIIDMQGTISDMQGNIGDMQGSISGIEGTISGMQGNIGDMQGSISGIEVTISGMQ
                     GNIGDMQGEIKGVNSRLDNMEPNIKDLKTGQVETSSKLNTIQSDVTEIKSDVKINRNT
                     LDTIIKHTSSLVEDTSDIKNDLNNIEIVTSKNWNDIAKLKSVK"
     gene            5237..5650
                     /locus_tag="PC592_002672"
     CDS             5237..5650
                     /locus_tag="PC592_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF4056623.1"
                     /translation="MKMPKENVDMIMFAPCGMNCIVCYKHCYHKKPCAGCLNSNMGKP
                     EHCRKCKIKDCVCQKGLFYCFECFDFPCKLIKNLEKSYNKRYQVSLLENSKFVQKYGL
                     EKFMEKQRERYTCSKCGGIISIQDRECSECREKMK"
     gene            5724..6260
                     /locus_tag="PC592_002673"
     CDS             5724..6260
                     /locus_tag="PC592_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF4056624.1"
                     /translation="MIGLKCGMVKLLKHQIIWDKSAKDVIILLKSILDKTAIDIQHIG
                     SSSIPSVSAKPIIDIVVGVASLEEAKLYIKKLEQRKIIFRGQDIPEQLLFVMGDLKKN
                     IRTHHIHVVEWNSFAWNNYINFRDYLNTFTEKAKLYDSNKQKLALQFEDNRKIYTQRK
                     QELISTLLEEARLWRMNT"
     gene            6421..7995
                     /locus_tag="PC592_002674"
     CDS             6421..7995
                     /locus_tag="PC592_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HDF4056625.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     QFDIGNVLPQDYYGLIVILGVILGVMGAFYNWFTLYVQYLYKKIPKIGTFGKLLIPFI
                     MAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGSGAPGGIFF
                     PLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTGIILIFEMT
                     GSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGEKILDQFSV
                     MFGSPVANKAIQDIQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMTDERDSGAV
                     YDKMENLCKEHTSHIF"
     gene            complement(8684..9289)
                     /locus_tag="PC592_002675"
     CDS             complement(8684..9289)
                     /locus_tag="PC592_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea carboxylase-associated family protein"
                     /protein_id="HDF4056626.1"
                     /translation="MINWNLWRTLNMEYIINPCSGIKIKVTKGQKIEIVDIEGGQVVD
                     FFAEMQDDSAEFISPGVTIDCNESLRLQVGNLMYSNKYKPMFKILYDDVREHDLLHPC
                     CKLEMYDFFYNNGENHPNCFDNINQALGTSHQIIHPINLFMYTKLNTDGSIEVCEPLS
                     KANDKIVLEALENMTLGIAACSVSESSCNSRKCTSIKIVVD"
     gene            9660..10229
                     /locus_tag="PC592_002676"
     CDS             9660..10229
                     /locus_tag="PC592_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF4056627.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTEILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESSGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPSVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKMLYSNRYN"
     gene            complement(10566..11840)
                     /locus_tag="PC592_002677"
     CDS             complement(10566..11840)
                     /locus_tag="PC592_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF4056628.1"
                     /translation="MTFLLYKLTSYFIDFRNHWIFKIILIYGYSIISQMIIWISDPVN
                     ILFTLFGYFVLLIICSKSRLIPIVSVIMILYPIIVGINFLFINNPLYRELIISKEYIL
                     ILSIVQIVSALIKLLFWFLIHIFLKNRLVNIKQYLSNKIWIFIDMVCISSFLSILIAI
                     ILPPTNLIPMGSNKNIILGNLSYGTYLIILSAILANIGVILLLQPLIENVKMKIEKQA
                     NHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLEIEDIAGAKKYFNQLKIGIGTL
                     SGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDNHLGIEPIDLCTIFSNSLDNAI
                     EASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPINRKQELFISDKKDSNSHGYGI
                     ENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
     gene            complement(12134..12310)
                     /locus_tag="PC592_002678"
     CDS             complement(12134..12310)
                     /locus_tag="PC592_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056629.1"
                     /translation="MFFTFIGVISAILLLCTIIYGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(12414..13022)
                     /locus_tag="PC592_002679"
     CDS             complement(12414..13022)
                     /locus_tag="PC592_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4056630.1"
                     /translation="MEKFLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINTSIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENHNNKKTEAEYRTIAYQITSF
                     IQLIFLRSNAFLKYSGIDILNVEQRNGLIDFQLDLFLVDITK"
     gene            complement(13118..13942)
                     /locus_tag="PC592_002680"
     CDS             complement(13118..13942)
                     /locus_tag="PC592_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4056631.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISTLQRIVLLRDSKFSIAEIANIIHDWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISIREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQPNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHRGEHNEINCENYLTEIQIPLIQV"
     gene            complement(14108..15001)
                     /locus_tag="PC592_002681"
     CDS             complement(14108..15001)
                     /locus_tag="PC592_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4056632.1"
                     /translation="MQLYNTPFNTNKNLIYFFTLTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEMGIKWPLLTILFFALTFIT
                     SLTIGNYFNVKTSDIDWRQIVILRPSQIAYMLLVSFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFSVQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDL"
     gene            complement(15255..15692)
                     /locus_tag="PC592_002682"
     CDS             complement(15255..15692)
                     /locus_tag="PC592_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF4056633.1"
                     /translation="MKIHVEQGINCDDIEITIKCSTLDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLRNNEKVIINRCYIKNIKEKLNI"
     gene            complement(15949..16098)
                     /locus_tag="PC592_002683"
     CDS             complement(15949..16098)
                     /locus_tag="PC592_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HDF4056634.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LLFKK"
     gene            complement(16103..16342)
                     /locus_tag="PC592_002684"
     CDS             complement(16103..16342)
                     /locus_tag="PC592_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDF4056635.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIRIGG"
     gene            complement(16667..16888)
                     /locus_tag="PC592_002685"
     CDS             complement(16667..16888)
                     /locus_tag="PC592_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HDF4056636.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVIKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            17467..17724
                     /locus_tag="PC592_002686"
     CDS             17467..17724
                     /locus_tag="PC592_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF4056637.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVTKLYGGTNTYIPTYNGL
                     FRYARNREIVKQFNGVNYNELAIRYNMCVSNIKRILNENSV"
BASE COUNT         6466 a         2257 c         2744 g         6522 t
ORIGIN      
        1 atagatattt atgaaagatt aattagaaaa ttttagaggt aaaataagaa caaaaaaata
       61 cttatttaat cttattaaag acctattaaa actactgatt ataatataga acaagtatac
      121 aatttttaag aataatgcta ttttaaaatt ctaaaaatta aggaggataa ttaatgggat
      181 atttaaaaga ggatagacaa gattattgtt gtgagtttgc tagaccatat gtcaatcgtc
      241 aaatttatga tgacacatac aatccaaaaa cagcattaaa aagaggtact ttatttcctg
      301 aattagattt aatagagtca aataactata atgattggct atatgcaaat cctaaaaata
      361 gagttagagc taaaaaaggg ggtaacatgt actaatgtca ttaaatagaa gagaactttt
      421 agagagaatt tcagaatatc aatttgcttg tatagaatta aatttatatt tagataacaa
      481 cccaagggat aagaaagctc ttgattcata taacagatac tgcgataaat ttacacaagc
      541 tgtgtgtgat tatgaatcta gatatggagc attaactaat tttggatatg aatcaagtga
      601 acatccttgg tcatggatat ctgaaccttg gccatgggat aaatcatttt ataaataaaa
      661 ttattaagat ttaaaattag aatttattat taaataatat attaaggagg agtaagataa
      721 tatgtggatt tatcaaaaaa cactggaaca tccagttaac ataagacaag cagaccctag
      781 aatggcaaaa tatatcatga ctcagttggg agggcctaat ggtgagctgg cagctgcaac
      841 tagatatctt caacaaagat atactatgcc aactggaaaa tctcgcgcac ttttaactga
      901 tataggtaca gaggaaatgg ctcatgttga gataatttct tcagtgttat atcaattaat
      961 aggcagttgt actccagaag aacttaaggc tgctggactt ggcagtaatt atgctaattt
     1021 tggacatggt cttcagccag tagattctaa tggagtaaat tttactacaa gttatattaa
     1081 tgtctttggc gattcggtaa ctgatttaca tgaggatatg gctgctgaac aaaaagcatt
     1141 ggctacgtac tatcaattaa taaatttaac tgatgacccc gatttaaaag atatattgag
     1201 atttttgggt gaaagagaag tcgttcatta tcaaagattt ggtgaagcac taatggatgt
     1261 ttacgagttt acagagtgta agcatcaatt ctaatgaact attaaaagtt gacagagagt
     1321 aagccttagt tttaatgaac tattaaaagt gaaccagaga gtaagcatta attctaatga
     1381 actattaaaa ataagaggta aaggttttag ttgatttcct ttatctctta ttttttactg
     1441 attaaacaga ttactttgct atttaaacat attattttat caaagaaaag ctcaatcaaa
     1501 aattcaaagc atcaccatag ttcaaggtat taccgttgtt ggcaagtttt ctacaatatg
     1561 ttttctttaa aacatttact aaaataactt atttgatgaa aaacaatttt tatagcagta
     1621 ttacttatta gctcatttgt acattttaga aattgagttt cttttaataa gcgaaactga
     1681 gtaaaatact tatggggtgt aatatttaga cttagtttaa agcatatgga gtactatgat
     1741 ttacttatat taacactgtt tgataagcat ttcaaagtta agttttcaca atagtgtttc
     1801 taaatataac gtaaaatttt ttgcatacag atattaactg tattttgtat tttattagtg
     1861 gcaaaacaat attttttatc ataataagcc aaatggaaca aatagaaact gatgtttcat
     1921 acatataaag ttcatttttt ctttttcaca gcctattctt acttcctaca tttgagagta
     1981 ttataatatt atttgatgtt atatcgatat ttttttgacc tatttagtga taaaattata
     2041 atatgagctt atctaaaagt taatatagta ggagggctat gatatatgaa ttttatatat
     2101 agtaatgctg aaatagagta tttaaaacat aaggataaaa tcttgagtga tataatagat
     2161 aaaatcggtc atatagagcg tgaaatagat acagacttat tttcgtcagt aatacatcac
     2221 attattggac aacaaatatc aacaaaggca caggctacta tatggaaaag aatgaaagaa
     2281 catttaaaag agataaatgc aagctccatc ttatctgctg gtactacagg attgcagtct
     2341 tttggtatga catatcgtaa agccgaatat ttaacagatt ttgctactaa aatccaaaat
     2401 ggtgaatttg atttacaaag tatcacttac atgtctgata aagaagcaat tgataaattg
     2461 acctcattaa aaggtattgg ggtttggaca gcagaaatga ttttattgtt ctgcttacag
     2521 cgtccaaata ttttcagttt tgatgattta gcaattcaaa gaggattacg aatggtttat
     2581 catcacagaa aaattactag aaagatgttt gaaaagtacc aaaaaagatt tagcccttat
     2641 tgtagtgttg caagtttgta tctttgggca gttgcaggtg gggtgataga tggaatgaga
     2701 gattacgctc ccaaaggtaa agtgagaaaa aatggttgaa tatatgcagg taaagataaa
     2761 actagtatga tatgaggata gatattataa cgaaagtgca atcaggagga aattatacta
     2821 gtatgttttt acataatggc aggtagaaaa gaagtgtcta atgactcgaa tgaaattttc
     2881 agaatataag gaggcattgt atgcaatata ttaactatta ccatagtcca attggaaata
     2941 ttcttttagc atcagataat attggattaa ctggtctttg gtttgagaat caaaagtatt
     3001 atgcttataa tcttgaccaa gaacatcagg aaaaagaatt gcctattttc gagcagacaa
     3061 agaaatggct agatatttat ttttcaggag aagaacccaa ttttacacca tcactccata
     3121 tggtaggtac tccttttcag actgcagtgt ggaagatttt acaacaaata ccatatggta
     3181 aaacaatcac ttatggagaa atcgcatata aagttgctca acaaaaagga atatctaaaa
     3241 tgtcagcaca ggcaattggt ggtgcagtag ggcataatgg aatctctatt attgttccat
     3301 gtcatcgtgt tgtaggaaca aacaggagtt tgacaggata tgctggtgga atcgatagaa
     3361 aaataaaatt gttatcttta gaaaaagtgt ctatgcaaca ttattttatc ccaaagaaag
     3421 ggagtgcatt ataaagtcat caaatttaga aattcttaat cattcctttg atatacaagt
     3481 atctgatttt gaaagcaata acttgcaatt taaaaaaaga ttttttagac tatatgttat
     3541 acaatattat ccatagtaaa cattatacaa ttttagagat aggttttgga gtttttattt
     3601 tatcattgta caaatgttca aaatatgttt ttggaaatga taagagtgtt aaatccaaag
     3661 gaaaaaatga aaacaagatt ttatcctttt ataagtgata agggtatgtg ttttaatcaa
     3721 agatggactt ttactttaat gctaaaaatt atatagccat attataatat ataagggaga
     3781 ggcacacctt tttagtgttc aatctccctt gttttttatt attatatcaa gactcattca
     3841 gtcgtgttaa ttttatgata aaatgagtat tttttaataa attatttata agtaaagtgt
     3901 gttatcggat aatcagtatt tttgtataaa atttggtata aatttaaaga agtatgtgaa
     3961 attttcaggt gtttttacta tagtatatta ttttactgat tttaatttag caatatcatt
     4021 ccaattctta gatgtaacta tctctatatt gtttaaatca tttttaatat ctgatgtatc
     4081 ttctactaat gaagaggtat gtttaattat tgtatctaat gtatttctgt taatttttac
     4141 atctgactta atttctgtaa catcactctg aattgtatta agtttactac tagtttcaac
     4201 ttgtccagtt tttaagtctt taatattggg ttccatattg tctaatctac tattgactcc
     4261 tttaatttct ccttgcatat caccaatatt accttgcatg ccactaatag tgacttctat
     4321 accactgata ctgccttgca tatcgccaat attaccttgc atgccgctaa tagtgccttc
     4381 tataccactg atactgcctt gcatatcgcc aatattacct tgcatatcgc tgatagtacc
     4441 ttgcatatcg atgatagtac cttgcacgct gctaatagtg ccctctatac cactgatact
     4501 gccttgcata tcgccaatat taccttgcat atcgctaata gtgccctcta taccactgat
     4561 actgccttgc atatcgccaa tattaccttg catatcgctg atagtacctt gcatgccgct
     4621 aatagtgcct tctataccac tgatactgcc ttgcatatcg ccaatattac cttgcatatc
     4681 gctgatagtg ccttctatac cactgatact gccttgcata ttactaatat taccttgcat
     4741 ttcctgcaat aactctaata tcttttcatc catcactatc acactcctat tttattatta
     4801 taacataatt taggagttgt attccacaaa cgctatatca tatttaattt ttaatcatat
     4861 cattatctaa tactcaaaac atggttaaat atgtttatat tgaaaacttt tttattaatg
     4921 aaccttatat tgtctaagtg tctaatatac tatgataagt gcttttgagg tatgtgtggt
     4981 tacatctgta tttaaagttg ctggtactat catatacttt taaataccac ttaagctatt
     5041 tatattgatt acttgtgttt gaatattttg attagtagat ttacttttat ctttttttat
     5101 tcttagtttt aaactttcat atttccttga aaatttattg acaattaaag tgcatgaatt
     5161 ttttagttac tttttatgtt acaatatgaa tatataacaa ttcgacaaat tggatttttg
     5221 aaaggagtaa aatgttatga aaatgccaaa agagaatgtt gatatgatta tgtttgctcc
     5281 ttgtggaatg aattgtattg tttgttataa gcattgttat cacaaaaagc catgtgctgg
     5341 ttgtttgaac agcaatatgg gaaagccaga gcactgccgt aagtgtaaaa taaaggattg
     5401 tgtttgtcaa aaaggattgt tttattgttt tgaatgtttt gattttcctt gtaaactcat
     5461 aaaaaatctt gaaaaaagtt ataacaagag atatcaggta agccttttgg aaaatagtaa
     5521 atttgttcag aagtatggtt tagagaagtt tatggaaaag cagagggaga gatacacttg
     5581 ttctaaatgt ggaggaatta tatctattca agatagggaa tgtagcgagt gtcgagaaaa
     5641 aatgaaatag ctaaatacct gtttatcaaa atagaaaaaa ttgtagtatg tatataaagg
     5701 ttgattatgt tgaggtggtt atagtgatag gtttaaaatg tggtatggtt aaattattga
     5761 aacatcagat aatatgggat aagagtgcaa aagatgtaat tatattgttg aaaagtatat
     5821 tggataagac tgctattgat attcagcata ttggaagtag ctctattccc agtgttagtg
     5881 caaagcctat tattgatatt gttgtaggtg ttgcttcttt ggaagaagct aaattataca
     5941 tcaaaaagtt agagcaacgt aaaattattt ttcgaggtca ggatatacca gaacaattac
     6001 tttttgttat gggagattta aaaaaaaata ttcgtactca ccatattcat gttgttgaat
     6061 ggaatagttt tgcatggaat aattatatca attttcgaga ttatctaaac acttttacag
     6121 aaaaagcaaa actctatgat agtaataaac aaaaattagc attacaattt gaggataatc
     6181 gaaaaatcta tacacagaga aaacaagaac taataagtac tttgctggaa gaagcacgac
     6241 tgtggagaat gaatacttaa aaagaataaa ttccaattta ctgagaaatt taacgataat
     6301 tttcttatac ttagtaaata aaaatctatc tttggtgatt aaaaaatagc tgtaaacact
     6361 cgtgactttg gtcatgggaa atttagattg tttagaatta ttggatgaag gaggaaacgt
     6421 atgaaaaagg atacatctca tattataaaa cgggcagagc actttcaggt aattttgatt
     6481 ggagaaggac ttatggttgg tgctgtggct ggtttgattg tgcttttata caggatactt
     6541 ttagggcagg ctggtacttg gcttagccaa attttaaaat ttgtagaagg ttctacaata
     6601 aaaataatag cttggtttgc agtgcttgca gtacttgcat ggattgtatc aaagttggtg
     6661 gactgggaac caatgatttc tggaagtggt atacctcagc ttgagggtga aatgacaggg
     6721 aaaataaaac aagtatggtg gcgagtgttg ccaacaaaat ttattggggg attcttgtca
     6781 cttatgggtg gtcttgcttt gggaagggaa ggtccttcca ttcagcttgg tgctatggca
     6841 ggtaaaggta tttctagagc acttgaccga ggaaagaccg aggaaaaatt cctgttaacc
     6901 tgtggagcaa gtgctggatt atcagcagcc tttcatgcac cactggcagg tgttatgttt
     6961 tcacttgaag aagtccataa aaacttctca gtatctgttt taatttctgt aatgacagca
     7021 tctttgacag cagactatat ttcagccaat ttcctaggaa tggagtctgt attccaattt
     7081 gatattggaa atgtattgcc acaggattat tatggattaa tagtgatttt aggtgttatt
     7141 cttggagtta tgggagcatt ttataattgg tttactctat atgtgcagta tttatataag
     7201 aagattccta aaattggtac gtttggaaaa ctactgattc catttataat ggctggtatt
     7261 cttgggcttg ttatgcctga tgtgctgggt agtggacaca atttagttga agaacttaca
     7321 agtcatgaat atatttttgg aatggttgtt ttgatttttg tcatacgttt tatattttca
     7381 gctgtaagtt ttgggtcagg tgcaccaggg ggaatctttt ttccactact tgttttaggt
     7441 gcatttatag gtggaatatt tggtatggta ggtgttaaag tttttggaat gaatccagat
     7501 tatgtaaata actttgtgct tttggctatg gcaggatact ttacagctat tgtgcgtgct
     7561 cctctgactg gtatcatatt aatttttgaa atgacaggtt ctgttagcca aatgctttca
     7621 ctatcagtaa tttcaattgt ggcatatatt gtggctacac ttatgaagtc taaacctatt
     7681 tatgaaagcc ttcttgagag gttacttgaa aaaaatggag aacctgtaca taaagagagg
     7741 ggcgaaaaga tactagacca gttttctgtt atgtttggtt ctcctgttgc gaacaaggca
     7801 attcaggata tacagtggcc tgaaaattgt cttttggtag caattcaaag aggaggagaa
     7861 gaaattattc ctagaggtaa aacaattctt agaccaagtg atgtaattgt gactatgaca
     7921 gatgagagag atagtggtgc tgtgtatgat aagatggaaa atttatgtaa agaacataca
     7981 tcacatattt tttagggata atgatgaatg tttaataatg atagaatatt taatgaagat
     8041 ttgataatta aaaattggta atttgaaaga gaattaatga gttaatataa taaaatgaaa
     8101 atgtgatatt ttagatgtaa aagagtttga agaaaagagc tggatgtatt tgttaatgag
     8161 attatgtgga ttaatggtat atttatattg tgctaaaagt tagtctattg tatgagtaat
     8221 gggaacaaag ggcttgaaaa aaataggtag aagatttttt agatattctt attgggatat
     8281 tttaattaat atattttgat tgcgatattt tgggaagaat agaatttatt tataaatgaa
     8341 aataattaaa aggggttaag gttagatgaa tatcgataag gaagtattat tagataatta
     8401 acttaacatc taacagatag agtttttatg aaaacagtgt gtattgaaat aaaaaggtac
     8461 acgctgtttt ttcgttctgt tacgcaatag aatgctattt tttagagtac gagtataaaa
     8521 cccatattcc cttgtaattg tgtctgaaaa acatcataaa atcaagggat ttttacacat
     8581 aaatgtgtaa cataccataa ttaattgagg acgcaagtgc ttattctttt gcgcccttga
     8641 tggtattttc tgatttttat atttatttga taaatgaaat ttgtcaatca accacaatct
     8701 taatagaagt acattttctg ctattgcaag aactttctga aacactgcac gcagcaatcc
     8761 ctaaagtcat gttctccaat gcttcaagaa caattttatc attggctttt gataaaggtt
     8821 cacatacttc aatacttcca tctgtattga gttttgtata cataaataaa ttgatggggt
     8881 gaatgatttg atgggaagtt cccagagctt gattaatatt atcaaaacag tttggatgat
     8941 tttctccgtt gttataaaag aaatcgtaca tctcaagttt gcaacatgga tgcaataagt
     9001 catgttccct tacatcatca tataaaattt taaacatagg tttatactta ttagaataca
     9061 ttaaatttcc aacttgtaat cttaatgact cattacaatc aattgtaacc cctggagata
     9121 taaattcagc tgaatcatct tgcatttctg caaaaaaatc aacgacctgt cctccttcaa
     9181 tatccacaat ttcaattttt tgccctttag ttactttaat ttttatacca ctacaaggat
     9241 tgattatata ttccatattt aatgtcctcc ataaattcca atttatcatt ctgttctatg
     9301 ttctcatttt aacacatact ctgtctcttt tctatttgtt tcttgacgtt tataacatag
     9361 tctatcattt tttaattttc ataaaggtgt tgtagtcttt tttcaagatt acagcatttt
     9421 tttgcttaaa tttggcattt tcgtaatatt actgtattta gaagtaagaa aaaatattct
     9481 atatttaaat agatataaaa gtgtaagaaa ggtaaaaatc tgttataata cattaaaaac
     9541 taaatttaga aaaatttata taattagaaa aatgatttga taaaaaataa agttaaatac
     9601 taactaagta aatttgaaga agaaaaaata tgaaatacaa atttaaaagg aggtaactaa
     9661 tgaaaaagaa gttggaagat atgactttag aggaattatg gaacttgttt cctatatttt
     9721 tgactactca caaagaatgt tggaaaaatt ggtttaaaga agaacaatat agactaactg
     9781 aaatattgcc aatgcaaaaa attgttagaa taagtcatat tggaagtact tctgtgagta
     9841 cgatttatgc caagcctatt gttgacatac tgattgagat aattcctgat tataatatga
     9901 aagatattaa agatttgatt gagtccagtg gatatatttg tatgtctgag agcagtagta
     9961 ggctttcact taataaaggg tatacagtag atggatttga agaacgagtt tttcatttgc
    10021 atataaggta tgtaggtgat aatgatgagt tgttttttag agattactta attgaccacc
    10081 caagtgttgc aaaggagtat gaaaaactta agttggatct ttggaagaag tatgagcata
    10141 atcgtgatgc ttatacagat agtaaactag attttgttag ggagtttact gaaaaggcaa
    10201 agatgttgta ttctaataga tataattaga aatagatata attagagatt tatcttatat
    10261 atcgcattgt attttttaag aaagtaatta atagaaaaag ggattgtttc aaaatggaga
    10321 gataaatccc tttttcattg ttggaatggt aaaaatatat ttgatttcat ataaaaaaga
    10381 gtgcctcatc aactaaaaag tttattttga gacacataca tttttactaa ggtaaataaa
    10441 aatatcacat ttgattaaat tttaagttaa tgaatatatg tgcaaatatt taattataag
    10501 ttagtacaat tttaatcagt ataaaacaat ctaatttata ttatataaga taatctaatt
    10561 ttagactaaa ataatctaat ataaagaaat aaagaaaatt cattctcagt ataagagata
    10621 tccaattttc cattgtactt attaacaatt tctctaatat tctcaatacc atatccgtga
    10681 gaattactat cttttttatc cgaaataaat agttcctgtt ttctattgat aggatttacc
    10741 ttgttgtttg tcaataaata gctaaaatac tccttctcac aacgtgcctt taataccact
    10801 tttctatttg acaaatcagg aattttcaaa gatgcttcta tagcgttatc taaagaattt
    10861 gaaaaaatag tacataaatc tataggttct atacccaagt gattgtctat atctatatta
    10921 aagtgcacat caacaccatt ttcttccaaa cttgtatgac gaagatttaa aattgagtta
    10981 agagcttggt ttttgcaaaa ttgtttgcca ctaagagtac ctatacctat ttttaactga
    11041 ttaaaatact ttttagctcc agcaatatct tcaatttcta aatacgattc aatcatttga
    11101 aagtgattat tcatatcatg tcgcattttg cgtatttgaa tttgttgatt ttctagtaag
    11161 ttatagtatt tttcttttag gtgatttgct tgtttttcta tcttcatctt tacattttca
    11221 atcaatggct gtaaaagaag tataacacct atatttgcca gaattgctga caagatgatt
    11281 agataagtgc cataagataa gttgcctaag ataatattct tattactacc catagggatt
    11341 aaattagtag gtggcagaat aatagcaatt aatattgata aaaatgaaga tatacatacc
    11401 atatcaataa aaatccatat tttatttgat aagtattgct ttatattaac caatctattc
    11461 tttaggaaaa tatgtattaa aaaccaaaat agtaatttaa taagagcaga aactatctgg
    11521 actattgaaa gtattaaaat atactctttt gagattataa gttccctata caaagggttg
    11581 tttataaaaa gaaaattaat cccaactata atagggtaaa gtatcatgat aactgatact
    11641 atgggaatta atctgctttt gctacatatt ataagtagta caaaatatcc aaatagagta
    11701 aataaaatat ttacagggtc agaaatccat attatcattt gactaataat agagtaacca
    11761 taaatcaata tgattttaaa aatccaatga tttctaaaat ctataaaata ggaagtcaac
    11821 ttataaagta aaaaggtcat agagtaagga gtgttgtatt gtaaaaaata gtgtaaataa
    11881 tgtagagtaa atggaagaaa aggagttata gagcagtaag gttattaaga ctctgcaata
    11941 caacaaaata ctataataaa ataaataagc ctctgtaata taataaaaat tagtaataaa
    12001 taagattcta caatataata aaaatactat aataaaataa taagcctctg taatataata
    12061 aaaatactgt aataaataag actttgcaat ataataaaaa tctataataa taaaacccaa
    12121 cataataaag acattaattt cttactaaaa aagccactac aatcaacagt gaaaaagcga
    12181 ttgaaagtat tgaaaaagta aagtgagaat tagagtcatt attacgatta ttaagtttta
    12241 tccataaacc atatataatt gtacacaata ataaaattgc tgatattact cctataaatg
    12301 taaaaaacat caaaattcct cccccttatc taattcaagt atttttagtc tatgagaata
    12361 ttttcaagca ttaccataaa ataaaaaaat gtacataaaa aatcaatata gtattatttt
    12421 gtaatatcta ccaagaataa atctaattga aaatctatta aaccatttct ctgctcaaca
    12481 ttaagaatat caataccact atacttaaga aaagcattag aacgaagaaa aatcaactga
    12541 ataaatgaag ttatctgata cgcaatagtt ctgtattcag cttcagtttt tttgttatta
    12601 tgattttcat agtgagcctt aattaaaggt agtatctcaa atggataaac aatttcttct
    12661 tgtattaata tatagggcac agaaatcttt ataaattgac tatgctcacc tataaaatca
    12721 aaaaatgcaa ttagtatttc tcttaattgc tgtttaggtg ctaagttttt agtatcatgt
    12781 gtagccttat attcatccat gtgacgcttt aaaaattttt taatagaagt attaattaac
    12841 tcctctttag atttaaaata ataattaatc atagctaaat tgacatttgc tttagccaca
    12901 atttctctag ctgtaatact tgaaacatct ctatgtgaag atagtaactg gattgtagca
    12961 ttaattaatt gttcctttgt tgaatctgct ttcataattt ttccccttaa aaatttctcc
    13021 ataaaaaaat taaacatgtt taacacacgt ttagatacta tcatgaaaat tttgggatgt
    13081 caatgggtta ttagtactta tatacttaag tactaattta gacttgtata agagggattt
    13141 gaatttctgt aagataattt tcacaattta tttcattatg ttcaccccta tgaccgattt
    13201 gtctatttat acccgatatt tgataatcac tatttttatc taaccaataa cagaacgatt
    13261 catatgcacc agctatattt tcatatggac catacaccat ggtacatgcc atcatatcaa
    13321 tttcttctgt ctcacgatat ataaatccag atttgttttt tccaattttc tttacaacca
    13381 ttccaacttc aatatctaca ccattatctt tgacttcttc atcatggtaa aaagctatat
    13441 tattgttggg ttgacgtgat acttctatat gttcctcttt aataaattta gataactttt
    13501 cccagagtat accttcagat tggtagtctg ggattatctc tctaattgat atgattttat
    13561 aacttggaat tttcttaaat acaacattgt aatgaatttc atctttatca cagtttatag
    13621 cttctataaa tttatcaatt ttatttattc tctgttgttc ctgctttatt tccttttgta
    13681 tttcattctt ttttctattc aattccttaa ttacaaattc atcattccaa tcatgtataa
    13741 tatttgctat ttcagcaata ctaaattttg aatctctcaa taatacaatt ctttgtagtg
    13801 ttgaaatctg ttcaactgag tataatctat gacctgtata tttatctatt tctgccggtt
    13861 ttaaaatacc aagttcatca taataacgca acatacgaat agaaatttgt gttagttttg
    13921 aaacctctcc tattttaaac atgaaaatat gacctccttt tcacttataa tcagtatata
    13981 ttttgttttt atatacttca agagtttgtg gaggtacaat tattttccag atgtcgcaat
    14041 aaattatatt taagtagtaa tcgtatcaaa ttatagatta tcttaaattt tataattcat
    14101 attaaaatta caagtctaac tcaaattcaa aatcatccga ttttatctgt tcaatttcag
    14161 aatttacctt ttgtttaaat ttattagaag aaatcatata tacaagaaat attagaccaa
    14221 atattatttg tacatattga gctattacac acaatttaat agggtagtgt agaagtaatt
    14281 gaacgctgaa aaaatagtac atcatatgaa ccaacccagc cgataaaatg cttctactcg
    14341 tatttatata tacaaaatta attataaagt ttaaaagtac aatgtttggt ataaataaaa
    14401 aagcatcaaa tagggagtat tgtgccaaat tatatggtat ttgattaggt gtaaaatacg
    14461 accctagata ccagattcca caaacaagcc ctaaaataat tgaagagcct ataaatccaa
    14521 atctaactaa taatttgtca atggcgtatc ctctccatcc agcttcttga ctaagtatac
    14581 tcaatataaa acttactaat agcatataag ctatttgaga aggtctaagt attactattt
    14641 gtctccaatc tatatcagaa gtttttacat taaagtagtt tccgattgtt agagaagtaa
    14701 taaaggttaa agcaaaaaat aatattgtta ataatggcca ttttattccc atttctttaa
    14761 agcttaggta tctataaatg aagtcttgtt ttgcactttg tggatagatt gtagaaataa
    14821 aaaatagacc tacaatagct ggtgatgtat acgcaagata aaaaatgatt tctccaagta
    14881 tcgtatttgt aattccgagt aatgcaggtg taagactgaa tatccagttc aatactagag
    14941 taagtgtaaa gaaatagatt aaatttttgt ttgtattaaa tggggtgtta tatagttgca
    15001 ttttttcact atcctttcgt tttataatgg aatttgaatt tttattgatt gtttatttat
    15061 ttctatatgt attgagttat cgtttaatgt tagttattga ttataataat atcctattct
    15121 tattttgatt aattgttttt acactaaata taatcaatta atatttaata ttgaacatat
    15181 tatattattt ttaattatta aataggtcaa taaatttgca attagtgata ttaataaagt
    15241 actttacatt tttattaaat atttagcttt tctttaatat tttttatata acaacgattt
    15301 ataataactt tttcgttgtt tcttaaagta gcttgcatac gattatgtga tattactttt
    15361 atacttttta tgtagtccat atttaaaatc atggatttgg atattcgtga gaaggatgta
    15421 ttagctaata attttgataa tttatatatt tttaaatcaa tttcaaatac atcatcttca
    15481 taataagcaa atgttttatt tccaactgtc tcaaagtata aaatatcaca gacattgagc
    15541 ttataaatct ctcctgattt tttacccttt atatcaagta atggtgtact caataatgaa
    15601 attatttttt caatgttatt atctagagta gaacatttta tggttatttc aatatcatcg
    15661 caattaatgc cttgttcgac atgtattttc attaatcttc acctcatttt attactgtca
    15721 ttagaatagc attatatctt attgagtcca actagatgcg ttctaaattt caaattaagt
    15781 atagtgaaat tcaaaaatga aacggtgaaa ttcaaatttg aggtggtaaa attcaaaaaa
    15841 atactatgga tatttgggta aattatccaa atatcctagt atttttcata gaatatatct
    15901 aactatttta caaatagact tattttatga cttacatata ttgtcaaatt acttcttaaa
    15961 tagcaaaata tttttggata gtgtatcaat actgtttgat aaagtattta atttaccctc
    16021 aattctaacc aacaaataca tggacagagc tataggaaaa ccaacattgg ttattaacag
    16081 ctgtaaacta tcatccataa aattagcccc ctattcttat aactaaatca taaggagtgg
    16141 tatttgtttc cacaactttg gcttcaacaa cagaagctag gtcaaatcct ccaactgaaa
    16201 aaatattttt agatactatc aaatccatga cagattttat attttcttca gttaaatcat
    16261 cctttggatt ttctatagaa aaagaaactt gtttatcctt tacattttta aaactcatga
    16321 ctaatttttt cttaatttcc atataattac ctccgatata ataatttata ttttaattgt
    16381 ttgattgtta atattaattg tttatactag ttattgctga tatagaaaat gtttaattta
    16441 tttcaattaa ttagattgaa gtagggtagc atttaaaata gctaacatgt ttaagttgaa
    16501 atacgtttaa tatattaatt tttaaagtat caatatatta aagttataac tcaaattgaa
    16561 attataacct gccaaatcta cagcgtatta agtgcgttac ataactaaat cttttatata
    16621 aagagttaat tttttaattt gcaaatcaga ttatgtttaa aagacactat ttagatagtg
    16681 atgtgctatc taattttaaa atatctacaa tagggttctc ttgaagactt gctattgctt
    16741 ctgcaacagc ataaacatcc tcatttaatg cctctgcttt tacgtttgca aatgatttac
    16801 ttttaataac tgccttaccc ttatcgtcaa aaccagcatc caattttagt tttatactag
    16861 ataaattttt tgttgaaaca acttccataa aattacctcc taaaaattta atttcaaaga
    16921 tttgtcgact ttctttgtta gctataatac tatcatctaa gataatatcg gagttaaaca
    16981 gtaatttcta aagatttttt gtgtaaattt ttataggaaa aattttcctt atgaacaata
    17041 ataagtttac aaattattca tgaagatatg tttttagcgt tttgaaatag tatttgtata
    17101 tattcctaat ttagttggga tagttttgta tagaatttta tatgtataga gttaagtgtt
    17161 agaggttaaa gtttgtataa aattaaatgt taaagtctat gttaaaaatt ttattaaatt
    17221 taatctgtaa ataaaaaagt taaaagtcca atattaacat tttactttta aaccattaaa
    17281 atctttatta aagctaacaa agttataagt tataagaaat tttattaaag ttaatacaga
    17341 aattaatttt aaagctaaga aattttttgt taggtccaat aaaactaata aatatagttt
    17401 agtcaataat gtattaaaca aaaactttgt taagtctata aaaatatatt aaaggaggtg
    17461 taatttatga agataaaagt ggaagatata ccagttcaat ttcatgcaat ggtagaaata
    17521 atcggaattg ataagttcat agaggttacc aagttgtatg gaggaacaaa tacttatata
    17581 cctacgtata atggactttt tagatatgct agaaataggg aaatagtaaa acaatttaat
    17641 ggagtcaact acaatgaatt ggctattaga tataatatgt gtgtaagcaa tattaagcga
    17701 atactcaatg aaaatagtgt ttaagtataa tgaaaatagt tttattaaat gtaagtgtaa
    17761 tgataaagaa gatgttttat aaagtttttt tagacaaatt aactaaattt actacttatt
    17821 aatttaaata cattgtatat tctgtaaaaa aatttgttag atactgaaga tacattgaga
    17881 atacaaagaa aatagtcgaa aatatttgtt ggctaaaaaa tagataaaat gatacaattg
    17941 cttgtataaa agggaaaaat aaataaataa actatataaa taaagaaat
//
LOCUS       DAMKOJ010000069        17435 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.075, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000069 DAMKOJ010000000
VERSION     DAMKOJ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.075"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            241..1431
                     /locus_tag="PC592_002687"
     CDS             241..1431
                     /locus_tag="PC592_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056638.1"
                     /translation="MQKNVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNDCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGIVLLAFTIFGAMLVSKAATAMTIA
                     ILLCTLTIFIVGIKAKAPEITEILSNRTSFTPGYFKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMILSFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     IENL"
     gene            1607..1996
                     /locus_tag="PC592_002688"
     CDS             1607..1996
                     /locus_tag="PC592_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5071 domain-containing protein"
                     /protein_id="HDF4056639.1"
                     /translation="MENIEELLPKDKFDNSNIEKLKLLSDEEIRPICYRLLEWMQDYN
                     WPVAKEILPVLALHQELITPLIIDVLTEEDDDWKYWIISCLLPLFADKNLEPIVPFVK
                     RIAENPTKWECEAEVDEIAKVFLKRIL"
     gene            complement(2219..3328)
                     /locus_tag="PC592_002689"
     CDS             complement(2219..3328)
                     /locus_tag="PC592_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF4056640.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKINRRIIEL"
     gene            3791..4984
                     /gene="nifV"
                     /locus_tag="PC592_002690"
     CDS             3791..4984
                     /gene="nifV"
                     /locus_tag="PC592_002690"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF4056641.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            5009..6934
                     /locus_tag="PC592_002691"
     CDS             5009..6934
                     /locus_tag="PC592_002691"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF4056642.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIDGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKENNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLSNGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6956..7951
                     /locus_tag="PC592_002692"
     CDS             6956..7951
                     /locus_tag="PC592_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF4056643.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHDVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIL"
     gene            8280..8753
                     /locus_tag="PC592_002693"
     CDS             8280..8753
                     /locus_tag="PC592_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4056644.1"
                     /translation="MLGSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNILKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTNKSLEVYELIIEEENRSIEICFKNFTDEEKQVVTKLLEKMSKNAENEWFKVKR"
     gene            8787..9281
                     /locus_tag="PC592_002694"
     CDS             8787..9281
                     /locus_tag="PC592_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4056645.1"
                     /translation="MIRKANMNDLESIMKIIKSTVKEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKKGI
                     ASKLVDFAEKLARENNVLYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            9360..9899
                     /locus_tag="PC592_002695"
     CDS             9360..9899
                     /locus_tag="PC592_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4056646.1"
                     /translation="MKGMIYVIEFLKKRRSIRKYKDIEVEKEKLDKILKAALLAPSSK
                     GLRTWEFIVVDDKEKLIKLSQCRTKGGGFFLKNAPLAIAIIADKEKNDVWIEDASIAA
                     SYIQLQAHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPDKYSVECIISIGYPDEE
                     KKAYSDSDLDYEKVHFNNF"
     gene            10088..10399
                     /locus_tag="PC592_002696"
     CDS             10088..10399
                     /locus_tag="PC592_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056647.1"
                     /translation="MGIFKTKIDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKNLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            10427..11113
                     /locus_tag="PC592_002697"
     CDS             10427..11113
                     /locus_tag="PC592_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4056648.1"
                     /translation="MKYSYKKCIIDSILLMLIVQLLRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNSILIEKCKLILFVVVLSLA
                     IISTYCTKGYVFFNVTMMTLSVFIVPIFEELFFREYIWNYLSNFIKSKIKIICITSIL
                     SGIYNIGYIDIIRNYIALYNNSSYTFEVIISKIIIGTVFGIVLGLVRYRFRDVRLCIL
                     LRSLFAIFIR"
     gene            11345..12229
                     /locus_tag="PC592_002698"
     CDS             11345..12229
                     /locus_tag="PC592_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF4056649.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YDYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEQPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DVVECKVEGIGVLKNIVD"
     gene            12328..13503
                     /locus_tag="PC592_002699"
     CDS             12328..13503
                     /locus_tag="PC592_002699"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF4056650.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGIPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDNAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            13631..14485
                     /locus_tag="PC592_002700"
     CDS             13631..14485
                     /locus_tag="PC592_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056651.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWILDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINAGIIEVKKEYELRLNGIKVEKLDL
                     PSSSIAVVKFHENKVEYFLLGDCTLFIKNGESKVIKDRSICKFDNIVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKDGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKIPRFKVKDDSSC
                     LYLDIYND"
     gene            14528..15763
                     /locus_tag="PC592_002701"
     CDS             14528..15763
                     /locus_tag="PC592_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF4056652.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSDVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINKLKYQFKINI
                     DRAMNDFKPELIICHHLYLLTAFVRETVKDIKVMSICHGTCLRQLNTIDLEKEYIISN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSRDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELHDFENNLHNAIDSKIQSLLHNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            15865..16806
                     /locus_tag="PC592_002702"
     CDS             15865..16806
                     /locus_tag="PC592_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF4056653.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIKGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEEMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLING
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNIIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVA
                     LVSNKSDKSILSGASKVTAIGISDNSIIEQCLDAVKK"
     gene            complement(17023..17376)
                     /locus_tag="PC592_002703"
     CDS             complement(17023..17376)
                     /locus_tag="PC592_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF4056654.1"
                     /translation="MDRKRELKQLYKERKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SIKFQLGAGSCMIKELNNEWKKYGENAFTFEVLELIKHDDNKTKKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
BASE COUNT         6748 a         1851 c         3120 g         5716 t
ORIGIN      
        1 aaatctgtag aaattaacat taaaaaagat atttcataaa attaaaaaac gaagtagatt
       61 tgaacattct taaaaaataa aataaatata taaaaaatat ttaatataga tagggaaaaa
      121 agttgaaaat ataaaaatat tgggaaaata tagttgaatt taatgaacaa aaatgttatt
      181 gttttatcaa tgaagtgtta aaataaaaac atttaatatc attttaggga ggatgatttc
      241 atgcaaaaaa atgtaaagaa agcaaaagta acgggctcta tgttagccat ttttggcgtt
      301 gcaagcgttc tttttagttc acatgcagga ggaggatttg ctacagggaa tcaagaaact
      361 caatactatg tgcagtatgg atggacagca ccacttatgg caattttagc aatgattata
      421 cttactgcta ccatgagaga agttatcata atgtataata ataatgattg taggaattat
      481 aaggatttat tttgtgagct ttggagacca tatccaaaac ttgaaataat atgggagata
      541 tattactatc taatggtttt aatagctgta agtgctgtta tagcaggtgc agcagcagta
      601 tttcaaagta taggggtaaa ttattttgta gctgtattta ttattggaat tgtacttctt
      661 gcctttacta tatttggtgc tatgcttgta tctaaagcag ctacagcaat gacgatagct
      721 attctattat gtactcttac tatttttatt gttggtataa aagctaaagc accagaaata
      781 actgaaatat tatcaaatag aacgagtttt acacctggct atttcaagcc aatacttaat
      841 acttttattt atgcaggttt tcaatcagtt gttataccta cacttgcggg atgttcaaga
      901 ccacttctta agaactcaaa agaagctact aaggcaatga tactttcatt tgttatgaat
      961 gcaattgcat tagggcttgc tgtaactatg ctaatgggat ggtatagaga aattattgct
     1021 gctggtcaaa caacactacc tactctttat gttgcaggtc aatctggaaa tcatactata
     1081 tacataattt ataatgttgc attattcctt tgtttaatgt ctacaggagt aactactata
     1141 tttggtcttg taaatagatt tgaagaccat aaagcacttt ctttcctttc ttcaagaatg
     1201 aaaagaaggg tatttacagc ttgtgcaata atggtagtgt caatgcttat atcacttaca
     1261 ggattaagta atattgttaa atatggatat ggatattgtg gttatcttgg tttatttact
     1321 atagtaattc cattccttac attaggacat tataagaaca agaagtttgc aaaggaaaat
     1381 ccagaggcta aatggccagc ggaattaaac gaaaatattg aaaatttata aagtgagtag
     1441 tactttaaat aaaagatata atctaattaa taggtcgaaa atatagtcaa ataaaaatag
     1501 agtatattac tatttagata tgataaaata gggttgaaaa ataaattgat aaattaaaat
     1561 ttgaaagata taatgaacat aatgtattta ttaggagaat taagttatgg aaaatattga
     1621 agaattgctc cctaaagaca aatttgataa tagtaatata gaaaaattaa aattattatc
     1681 tgatgaagaa ataagaccga tttgctatag attattggaa tggatgcaag attataactg
     1741 gcctgttgca aaagaaattt tacctgtttt agctctacat caagagttaa ttactccatt
     1801 aataatagat gttcttacag aagaagatga tgactggaaa tattggataa tttcatgtct
     1861 tttgccactg tttgcagata aaaaccttga acctatagtt ccatttgtta aaagaatcgc
     1921 tgaaaatcca actaaatggg aatgtgaagc agaagtagat gaaatagcaa aagtattttt
     1981 aaagagaata ttataaataa tagttgaata tatttattga gattattttc aaaatttaat
     2041 attaaacaac ttggaaacag gtaatataaa actaacaata gatagaaaaa gctgtaatca
     2101 taaaggttac agctttttta tgcaatataa aatagtatta taataaagaa aaagttgata
     2161 cctgctttct gtatattata gtatttatat actattggca ttttaattag tccataaatt
     2221 ataattctat aattcttcta ttaattttag attctatagc tgtttctatt tcacttaaca
     2281 ttcgttcatt tttagggtca ataaaagcac atgtatagcc ttcttcacca gctctaccag
     2341 ttctaccaat acggtgtatg tagtcttctg gtgtttctgg taaatcgtaa ttatatatat
     2401 gacttactcc agatatatca agaccacgag aagctacatc tgtagctatt aagtattgta
     2461 tatctaaatt tctaaatgat ttcattattc tttctcgttt tgattgagca atatcactat
     2521 gaagtttttg acaattatat cctcttatag caagagcttc ttcaagatta tcaactcttc
     2581 tcttagtcct acaaaatatt attgccataa aaggattatc ttcatctagc accttacata
     2641 atgcatctaa tttttttcta tctgtagttt ctactacttc ttgttttata ttattaagag
     2701 ttatttcttc tttttgaatg gaaaccacaa caggattttt tgtgtaccta taagctaatt
     2761 tttttacttg agaatttata gttgcagaaa agcatagtgt ttgctttttg tttgaagttt
     2821 cttttaaaat ggcttccact tcatttttaa atcccataag caacatttgg tctgcctcat
     2881 ctaaaacaaa agtctttaac ttactaaggt ctattgtttt tctatttaga tggtctaaaa
     2941 gtctacctgg tgtagctata atcatatgaa tatttccctt tagtttcttt atttgagaac
     3001 caatatcttt tcctccatat gctgctagga tacttacatc tttagactct ttaagtttca
     3061 tagcttcttc tgttatttga atagctagtt ctcttgtagg agaaagtata agaacttgta
     3121 tatcatttat atctaatgat atattttcaa atatcggaag taaaaaagct agcgtttttc
     3181 ctgttccagt ttgagcttct gctattacat cttttccttc ttttattagt ttaatacttt
     3241 ctttttgtat aggtgtaggt gttgttattc ctgatttttt tagaatattt attgtatttt
     3301 cactaatccc taagcttttg aaatccattg ttatcttacc tttcatgaaa aattttcttt
     3361 tttattaatc aattaataat atcatattta taagtatttt tagtaaattt tttaattatt
     3421 atttatatgg cttaaaaata tataaagata ctttaaaatg aaatgtaact taaattaaat
     3481 tttagtagga attttatagg tttattttta aaggtttttt gaaaataaat ctatttaaaa
     3541 attaaattaa aatgcaagaa aaacataata actttcattt ttaagaagtt ttcacaaaaa
     3601 agaaaaaata tagtgcaata aatgatacaa agtaatataa tagattacaa gatatgaaaa
     3661 actaaaaaaa taaattgcaa atgaaattaa aatgaataaa aaataaaaaa ataatcataa
     3721 gttagaggta tcaatggaaa ataagaccta atgtttttaa aattaaaagt atactaaggg
     3781 gggcattaat atgtgcgtta tatcaaaaga tagagcaaag gaaataaaaa tagtagatac
     3841 tactttaaga gacggagagc aaacagctgg ggttgtattt gcaaatagag aaaaaataat
     3901 gattgctgaa atgttaagtg acctaggtgt tgaccaaatt gaagttggta tacctactat
     3961 gggtggagat gaaaaaaatg taataaagca catatgtagt agaaatttaa aatcagatat
     4021 aatggcttgg aatagagcag taataaaaga tgttgaagaa tctatttctt gtggtgttga
     4081 tgcagtagct atatcaatat cagtatctga tattcatata gaaaataaat tgagaacttc
     4141 tagaggctgg gttttagaaa atatggctaa aacagttgaa tttgcaaaga aaaatggact
     4201 atatgtttca gtaaatggag aagatgcttc aagagcagat atagacttct taactgaatt
     4261 tataaatgtt ggaaaacaag caggggcaga tagatttaga tattgtgata cagtaggagt
     4321 tatgaatcct ttttctataa agaatgcaat agaaactctt tatgaaagaa ctaattttga
     4381 tatagaaatg catacacata atgactttgg gatggcaact gcaaatgcac ttgcaggaat
     4441 agcagcagga gcaaattacg ttggtgttac agtaaatgga ttaggtgaaa gagcaggaaa
     4501 tgcagcatta gaagaagttt taatggcact taagtgtgtt tataaatgcg atttaaataa
     4561 tatagatact agaaaattta gaggaatatg tgagtatgta gcacaggcat caggaagaat
     4621 ccttcctaca tggaaaccag tagttgggga taatatgttt atacatgaat ctggtataca
     4681 tgcagatgga gctttaaaag acccacataa ctatgaacca tttgacccaa gtgaagtaaa
     4741 tcttgaaaga aaaatagtaa taggtaaaca ttcaggaaga gctgcagttg taaataagtt
     4801 gagtgaatat gaaatgtata tttctccaga aaacgctacc aaactattaa atgctataag
     4861 agctacatct ataagattaa aaagaagttt aatggataaa gaaattcttc aattatattg
     4921 tgatatacta gcacatgaga agggtacaac agaagaagaa gcagttagag gttcatatat
     4981 ttaagatata attgtttagg aggaaaatat gggagataat atagtttata aaataattaa
     5041 aaaacatata gtagatggag aagctgttgc tggaagttca attggtataa aaatagacca
     5101 aactttaaca caagattcca ctggaacaat gacgtatctt caactagaag ctatggggat
     5161 agacaaagta aagactaaaa gaagtgtggc gtttgtagac cataatatgt tacaacaagg
     5221 atttgaaaat gcagatgacc ataagtatat acaaacagtg gcagataaat atggagttta
     5281 tttctctaag ccaggaaatg gtatttgtca tcaagtattt ttagaaagat tttcaacacc
     5341 aggagataca cttttaggtt ctgatagcca cacacctact gctggaggtg tgggaatgat
     5401 ggctattgga gctggtgggt tagatgttgc tttagctatg gcaggaggag catactatat
     5461 aaaagcacca aaagtctgta aggtgaatct agttggaaaa ttaaataata tggtatcatc
     5521 aaaagacata atattagaag tattaagaaa acaaactgta aaaggtggag taggtaaagt
     5581 ttatgaatat ggcggagaag gtgttaaaag cctatctgtt ccacagagag ctacaataac
     5641 aaatatgggg gctgaacttg gagcaactac ttcaatcttc ccaagtgatg aaaaaacact
     5701 agaatttttt aagagccaag gaagagaaga tgcatggata gagttaaaac cagatgcaga
     5761 tgcagtttat gatgaagaga ttactataaa cctggatgaa ttaaaaccgt tagctgcaaa
     5821 acctcatagt ccagacaatg tagatgaagt tgaaaatata ggcaaaatta aaatagacca
     5881 agttgcaata ggaagttgta caaattcttc ttatgaagac ttaatgaaag tagcacaaat
     5941 cctaaaagga aataaagtac ataaggatgt gagtttggta atagcaccag gttcaagaca
     6001 agtgatggag atgattgcta gaaatggagc tttagcagat ataataagtg ctggagctag
     6061 aatactagaa aattcttgtg gtccatgtat cggtatgggt caatctccag gtactgactc
     6121 tgtgtcttta agaactttca atagaaattt ctatggtaga agtggtactc tatcagcgca
     6181 agtatactta gtaagtccag aagtagcagc agtaagtgca atcaagggag tgcttacaga
     6241 cccaagagaa tttgatatta aatttaccaa tttagatgta aatgaatttt tgatagatga
     6301 tagcatgata attaaacctg ctgatgtagg aagtgatgta gaagtagtta gaggacctaa
     6361 tataaaacct ttccctctta atacagagct aagtcagtct atagatggaa aagttatatt
     6421 aaagacagaa gataatataa ctactgacca tataatgcca tcaaatgcta agttacttcc
     6481 ttttagaagt aatataccgt atcttgcaaa ctattgtttc aacactgtag atacagaatt
     6541 tcctcagaga gcaaaagaga ataatggtgg atttatagtt ggtggagata attacggtca
     6601 aggttcaagt agagagcatg cagctttagc accattatat ctaggtgtta aaggagtaat
     6661 agttaagagc tttgcaagaa tccacaaggc taacttgata aatagtggaa taattccaat
     6721 ggagttttgt gatgagaaag actatgaaaa tatatctctt ttagacaatt tagagatacc
     6781 aaatatttta gacaatctaa gtaatggaat tttagaagtt aagaatacaa ctaaaggaac
     6841 ttcttttaag gttaaagtag aattatcagc aaaagaagtt gatgtattaa aagctggtgg
     6901 aaaattaaac tatactaaaa atcaagctaa ttaatatgaa aagagggaat attgaatgta
     6961 taaagtgaca cttataccag gagatggaat aggaccagaa gttgcgaaag ctatgaaaaa
     7021 ggtggtagaa gctactggag tagagataga atgggaagaa gttaatgcag gagaggcagt
     7081 tattgaagag tatggcactc cacttcctga atatattata gacagtataa aaaagaataa
     7141 aatagctata aaaggtccaa ttactactcc tgtaggtaaa ggatttagaa gtgtaaatgt
     7201 aactttaaga caggcattag atttatatgt caatttaaga cctattaaaa gttttaaggg
     7261 tataaaatca agatatgaag atgttgattt agtagtggta agagaaaata cagaagattt
     7321 atatgctgga atagaacata aaataggtga ttatgcagct gaaagtataa agataataac
     7381 aagaagtgca agtgaaagaa tcgttgattt tgcgtgtaac tatgttaaag ataacaagag
     7441 aaaaaaagtt acagctatac ataaagcaaa tataatgaaa atgtctgatg gattattttt
     7501 agatgtgttt agagaagtag catcaaaaca tgatgtagaa tatgatgatt tgattgtaga
     7561 tgcagcagct atgaacttag ttttaaatcc agaaaattat gatgtaatgg taatgccaaa
     7621 tctttatgga gatatactat cagatttagg tgctgggctt gttggaggtt taggtataat
     7681 tccaagtgca aatattggta aagattgtgc gatatttgaa gctgttcatg gaagtgctcc
     7741 acaaatagca ggtcaaaata aagctaatcc aacagcactt attcagtcat cagtaatgat
     7801 gcttagatac ttaggcgaat atgaaaatgc acaaaaaata gaaacagctt tagaaaaagt
     7861 atttcttgaa ggaagcaaat tgactgtaga tttaggtggc tcagcttcga ctacagagtt
     7921 tgcagatgag gtgtgtaagt atattttata gattttgttt atggaaaaag tagaatatag
     7981 attaaaagaa aggggctttc tcaaaataga gagaagcctc tttctttgtt aaaatgataa
     8041 aatgtatttg attctatgca aaagagagtt cctcataaac gaaaaagttc attttgggat
     8101 gctcacttta attttaaaat tatttgatta ataggcaaat aaaggttaaa taaatttagt
     8161 gtttttaatt gaactttcaa ccaatatatg gtaaaattta aaaaagttga actttcaact
     8221 aaaaacaaat atattgatta tgtgaaattc tatgaataag gaactctgtg actttagtca
     8281 tgttaggttc agtggaggtg tgtttgatta agaccttaga tagtaatata ttaagagaag
     8341 taggtacttt atctagagca gtaaattcaa taaatgatat taagtacaag gaattaaagt
     8401 tacaaaaagg acaatttaca ttcttgacaa gaatttgtga aaatcctggt ataaaccttg
     8461 tggaattatc aaacatttta aaggtagaca aggctacaac aaccaaagct atacaaaagt
     8521 taataaaagc tggatatgtg gataaaaagc aggatgagtt tgataaaaga gggtataatt
     8581 taactccaac taataaatct ttggaagttt atgagttgat aattgaagaa gagaatagaa
     8641 gtatagagat atgttttaag aattttacag atgaagaaaa acaagtggta actaaattat
     8701 tagaaaaaat gagcaaaaat gcagaaaatg aatggtttaa agtaaagaga tagtaaataa
     8761 atacattaac ctaaggagat agttttatga ttagaaaagc caatatgaat gatttagaaa
     8821 gtattatgaa aattataaaa tcgacagtga aagaaatgaa gacttataat aatacacaat
     8881 gggatgaaaa ctatccatta gaaaaagact ttgtttcaga tattaagaaa caggacttat
     8941 atatatatga agtggatgga gaagtagcag gatttatatg tctcaattat gaagagccag
     9001 aagaatatct aggcttaaat tggtcatcta ataaaaaagc aatggtaata catagaatgg
     9061 ctgtaaatcc aaattttaga aagaaaggaa tagcatctaa gttagttgat tttgctgaaa
     9121 aattagctag agaaaacaat gtattatact taaagagcga tacgtattca ataaattcaa
     9181 aaatgaattt attacttaca aagtgtggtt ttataaaaat cggagaaatg agttttttag
     9241 gaaaggagaa atctttctac tgttatgata aaatattata aaaagcattt ataatacaag
     9301 gggtaaataa taaatttttg gtattagtaa gggtataata taacctagtg tatgccatta
     9361 tgaaagggat gatttatgtg attgaatttt taaagaagag aagaagtatt agaaaataca
     9421 aggatattga agtagaaaaa gaaaaattag ataaaatatt aaaagctgct cttttagctc
     9481 catcatcaaa ggggcttaga acatgggaat ttatagtggt agatgataaa gaaaagttaa
     9541 ttaaattatc tcaatgtaga actaaaggtg gcggattttt cttaaaaaat gcacctttag
     9601 ctattgcaat tattgcagat aaagaaaaaa atgatgtttg gatagaggat gcaagtatag
     9661 ctgcttcata catacaactt caagctcatg aactaggatt aggttcttgt tggatacaag
     9721 taagaaatag aatgcatgat gataatatag aagctgacaa atatattaga gaagaattaa
     9781 aagtacctga caagtatagt gtagaatgta taatttctat aggatatccc gatgaagaaa
     9841 agaaagcata cagtgactct gatttagact atgaaaaagt tcattttaat aacttttagt
     9901 atataatatg ttgtattaag acattatatt tttttatatt gttaatatat acttaaaatt
     9961 gtaaaaatat atctgaattt tactaactta tctatgggtt atgtacaagg attttaaaga
    10021 taaatataga aattaatgtt tataatcgat acataacttg agtaacaaaa tttaaggagg
    10081 ttaaagtatg ggtatattta aaacaaaaat tgatgaggac tggaaagtaa actacattaa
    10141 agagtttaat gaaatgagag attcttatga gagtaaactt caaaaaaaac agtttgaagt
    10201 agatagtttg aaatcagaac tggatagact aagaagctat aaaaatagcc ttaagccaaa
    10261 agaaaaacaa attactgatg atgatataaa taatataaag aatttaagaa gagatggttt
    10321 aagttataaa gaaatttcaa atcaaacaag ttggagcaag gcaactgtaa gtagagtatt
    10381 aaatggactt tacgattagc atatacatgg ggtgatttaa attgggatga agtatagtta
    10441 caaaaaatgt ataatagatt ctattttatt gatgcttata gttcagctat taaggatgat
    10501 tttgaattat gtacttctaa gtcaatttga atttactctt gaaaatttta atattataaa
    10561 cttaatttct tttacactag ttggattatc attaattcta tttttaaaag ataattcttt
    10621 gtataacaag gtgagaaata gaaaaatcac agaagctttt gaagaaaata aaaacagtat
    10681 acttattgaa aagtgtaagc tgatactttt tgttgtggtt ttatctttag caataatttc
    10741 aacttattgt actaagggat atgtattttt taatgtaact atgatgactt tgtctgtatt
    10801 tatagttcca atatttgaag agttattttt tagagaatac atatggaatt atctaagtaa
    10861 ttttataaag tcaaagatta aaattatatg tataacatct atattatctg gaatttataa
    10921 tataggatat atagatatta taagaaatta tatagcattg tataataatt caagctacac
    10981 ctttgaagtt attatttcaa aaattattat aggtactgtt tttggtattg tacttggatt
    11041 agttagatat aggtttagag atgtaaggct ttgtatacta ttgaggagct tatttgctat
    11101 atttattagg tagataatat aattagttta taaggttgtt ttaaatgtaa ttttaaatca
    11161 accttatttt atttgtgttc tataaagtac ttatgtagta ataactaatg aatttaataa
    11221 aaattatttg aatattttta aaatatataa atatgtattg acatataaat attatcaatt
    11281 acaatttata taaactagta aaaattaaat aatattaatc aacttattga atggaggaat
    11341 aaaaatgaaa tttgtgactt tttgtagtag caatgaagaa aaaataggtg tatttaattc
    11401 agaaacaaat agtatatatg aaattaatag tttaggatta agtaaattat atacagatat
    11461 gaatgatttt attgaaaacg tatctacagg agatttagaa aaaataaaaa acaattcatt
    11521 tgaaaatgca aagtgttata agttagaaga agttaaatta tgttccccaa ttgtaagacc
    11581 taaaaaagat attatatgtt taggtctaaa ctataaagac catgtcaatg aaatcccaga
    11641 tggagttata aaaaacgtag ttatgccaga ttatccaatt tatttttcta agagagcaga
    11701 taaaataatt ggagtagatg ataagataag tttacatgga gacttagtag aaaagctgga
    11761 ttatgaatca gaacttgcag taatcatagg taaagaaggt ataaatatat caaaagaaga
    11821 tgcttatgac tatatatttg gatatacaat agtgaatgat ataagtgaaa gagcactcca
    11881 agataaacat gttcaatggt ttagaggaaa aagcttagac acacatacat ctatgggacc
    11941 ttgcatagta cataaagaag aatttgaaca gcctttaaaa ttagatataa gtagtgtagt
    12001 aaatggagaa gtaagacaaa attctaatac agaatacttt atatttgata tacctaccat
    12061 aataaatgat ttatcaagag gaatgacttt aaaaccagga gatataattt caactggaac
    12121 tccagcaggt gttgctatgg gtatgaatcc tcaagtatat ttaaagcatg gtgatgtagt
    12181 tgaatgtaaa gtcgaaggaa taggtgtttt aaaaaatata gttgattaat ggataaatat
    12241 gccatataat tttattagta cgaataattt aattaatata ggattaatca aacttatgat
    12301 taatttatta tagagaggga tgagtatatg gcaagagaac tagaattaaa gtatggctgt
    12361 aatccaaatc aaaaaccatc aaagatttat atgaagaatg gagagcttcc tatagaagta
    12421 ttaaatggaa aacctggata tataaacttt ttagatgcat ttaatagttg gcaacttgtg
    12481 aaagagttaa aagaagctac aggtcttcca gcagcaactt catttaagca tgtaagtcca
    12541 gcaggagccg cagtaggaat acctttatca gatactttaa agcaaatata ttttgttgat
    12601 gatttagagc tttctccatt agcttgtgct tatgcaatgg caagaggagc agatagaatg
    12661 tcttcttatg gtgattttat agcactttca gatgtatgtg ataaagagac tgcaactatt
    12721 atagcaagag aggtttctga tggtataata gctccaggat atacagatga agcccttgaa
    12781 atattaaaag gaaagcgtaa aggtaactac aatattgtaa aaatagatga aaactatact
    12841 cctgaaccta ttgaaacaaa ggatgtttat ggaattactt ttgaacaagg cagaaatgaa
    12901 atattaataa atgaagacct attaaaagat attccaactg ataataaaat ttttacagat
    12961 aatgcaaaac gtgatttaat tatagctctt attacattaa aatatacaca atcaaattct
    13021 gtttgttatg ctaaagatgg acaagtaata ggagtaggcg caggtcaaca atcacgtatt
    13081 cattgtacta gacttgcagg taataaagca gatacttggt atcttcgtca acatcctaaa
    13141 gtattaaact taaaattcaa aaaggatata ggtcgtccag atagagacaa cactattgat
    13201 gtatatcttt ctgatgatta tatggatgtg cttgctgatg gcatatggca aaactttttt
    13261 gaagaaaaac cagagcctct aactggagaa ggaaaaagag catggcttaa aactttaaca
    13321 ggagtagcac ttggttcaga tgcatttttc ccatttggtg ataatataga gcgtgcaaaa
    13381 aggagtgggg taagctttat agcacaacca ggtggttcta ttcgtgatga taatgttata
    13441 ttaacttgta ataagtataa catagtcatg gcatttacta aaaatagatt attccatcat
    13501 taaaatactg aaaatataaa gataatatag attaagtaaa aatctacaac aagttttgtt
    13561 gtagattttt ttatttgctg tataatttta aatagaactt tatttttaga tattcaattt
    13621 ggaggttgat atggctttaa atataagaaa ctatagccta ttatgtaatc aagggacagc
    13681 taaatttaat gaagatgtag tcggtataaa tccatttgga gcatggattt tagatggtgc
    13741 tacaggactt aatggaaaaa atttagtgtc aactgaaagc gatgcaaggt ggtatgttca
    13801 gtggtggaat aggtatttat ataaaaatat aaataaagaa gaatcattaa agagtattat
    13861 taatgctgga ataatagaag taaaaaaaga gtatgaacta agattaaatg gtattaaggt
    13921 tgaaaaatta gatttaccat ctagttctat agctgttgta aaatttcatg aaaacaaagt
    13981 agagtatttt ttattaggag attgtacttt gtttattaaa aatggagagt ccaaagttat
    14041 aaaagataga agtatttgca aatttgataa tattgtattt gatgaaatga gcaaactttc
    14101 taacttggaa gagatggcat ttgatgagat tagaactagt gttatggata caatagtaag
    14161 taataggttg aagaaaaata cgaaagatgg atattggata ttggattttg atgaggaagc
    14221 tgtggaaaat tctatatatg gatacattga aataaaaaaa gattttcaat tgatgctaac
    14281 aagtgatggt tttacaagtg catgtgatag atataatcta ataaaagaag aagaattgat
    14341 acgtatagca gaaaaatttg gtatagggta tatacacaat aaagtaagag attttgaaga
    14401 taatgactat aaagcggtta aaatcccaag gtttaaagta aaagatgatt catcttgttt
    14461 atacttagat atatataatg attagactgt gtaaaactat ttaattttag aagggaggta
    14521 agtgaaagtg aaaattcttc atataataac acaaaaacca aatagtacag gtagtggtat
    14581 atatttgtct ggtatgataa aaggattcga aaagataggt cataagcaag ctgtaattgc
    14641 aggtatagat gtaaatgatg atgtaaattg ttttccaagt gatgtaagtt tttatccagt
    14701 aaagtataat tgtggggagt taaattttcc tgttgtaggt atgagtgatt ctatgccata
    14761 tgaaagtaca agatataaag atttaaatat agacatgata aataaattga agtatcaatt
    14821 taaaataaat atagataggg ctatgaatga ttttaaacca gaacttataa tatgtcatca
    14881 tttgtaccta ttaactgcat ttgttagaga aacagtaaaa gacataaagg tcatgtctat
    14941 ttgtcatgga acttgtttaa gacagctaaa taccattgat ttggagaaag aatacataat
    15001 atcaaatata agaaaattag atttaatatt tgctcttcat gaaaatcaga aatatgatat
    15061 tataaagact tttggagtaa gtgaaagtaa agtagttgta attggtagtg gttataatga
    15121 tgatatattt tataataaaa attataaaat aaaggatgat aaaataaaaa tagtatttgc
    15181 aggtaagata tgtaaatcaa agggactaat tccatttata aaagctatat ctaaattaaa
    15241 atatagtaga gatttaatag aagtcaattt tgcaggtact ggaagtgata tagaatcata
    15301 taatgagata gttaaactcg caagtaagtc tccatttaaa atgaatttcc taggaaagtt
    15361 agagcagaga gatttagctg agctattcaa caggtcacaa atatttgtgt tgccatcatt
    15421 ttatgaggga ttaccagttg tagttttaga agccttatct tgtggaacag atgtaatcac
    15481 tactgatatt cttggtgtta aagagtggat tggtagtgag attaataatt ctggaaagat
    15541 agaatatgtt tctctacctt ttatggagaa agaaggtatt ccaaaggatg aagagttaca
    15601 tgactttgaa aataatttgc ataatgcaat agattctaag atacaatctt tattacataa
    15661 ctcaaataaa aaaacatctg tagatatgtc aaaaaaaacg tgggatggct tagcctatag
    15721 aataaatgaa gttattttaa tggatgagtt gtgtttggtt taaatttatt tagattataa
    15781 aaaagtgtaa ctatttttac acttttttta aatgatttta tattatacta atactaaata
    15841 tatttgtttt tagggaggta atttatgagg attagtaaaa aggtattggc gttaggtatt
    15901 tcagcattat tgttaagtgt tagttttcca acatcaataa atgcactaga taagattgaa
    15961 aatattaaag gagtagataa atatgagaca gctgggctta tttcagataa gcaagatttt
    16021 acaacagcag ttcttatcaa cgcggattct acaatggtag atggtatcgc tgccagtggt
    16081 cttgcaggag taaataatgc agctatttta ttaactaata aggatgatat accagaagca
    16141 acacttcaaa gactgaatag agttactaag atatatgtaa taggtggaga aaattctata
    16201 agtaaagatg tagaagaaat gttacttatg agaagaatgc aagttataag aattgatggt
    16261 gtagatagag tagatacaag ttataaaatt gcaggtgaaa tagaaaaaat taaaaacagc
    16321 gataagatgt ttttgataaa tggatttaag gatgaagctg atgcagtaag tgttgcatct
    16381 gttgcttata gagatggagc tcctataata ttgacaaaag atataccttc agcagaagaa
    16441 gatacagact tagacccatg gtttggagtt tctcctgttc cagtatatgc tattggagga
    16501 gagtctacac taagtgatta catagtgagt agatatagag caactagaat tggtggtgtt
    16561 gatagatatc aaactaataa aaatattatt gaaaagttct ataatggagc aaaagagttc
    16621 tatataacaa gtggagacga tttagtttat gctttggttg catcaccact tgcaaaaaat
    16681 gctcctgttg ctttagtttc aaataaaagt gataagagta tattaagtgg agctagtaaa
    16741 gtaacagcaa taggtataag tgataatagt attatagagc agtgtttgga tgctgtaaaa
    16801 aagtaataga gtgtcattag taaaatgaat atataccatt gaaaattagt agatagttca
    16861 ttttataatg gtataaaata tatgagaaga ggctatcaaa tagagataag cctctttttc
    16921 attgttaaaa ttatgaaaat atatttattt cataaaaaag tatcacatga actaaatgtc
    16981 tattttgaga cactatctta ttttcttaga ttagatgatt ttttatatgg aataaatttc
    17041 ataagtatta tcttccttca atttttccaa ccaaaccatc tctaaaatat ctagttcttc
    17101 taaatagtct ttctttgttt tgttatcatc atgttttata agttctaaaa cttcaaatgt
    17161 aaatgcattt tcaccatatt ttttccactc attatttaac tcttttatca tacatgaacc
    17221 agcaccaagc tgaaatttga tagagttaaa tttgcttttt atgtcattac tttttccaag
    17281 gtaaatcttt ttagtaatat cattttttat tatgaataca cctgtgtcaa atttcctttc
    17341 tttgtataat tgttttaatt cacgttttct atccatgatt ttatatacct ctctttataa
    17401 ttaatatgta atatgtaaat ataaaaatat attac
//
LOCUS       DAMKOJ010000070        17263 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000070 DAMKOJ010000000
VERSION     DAMKOJ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17263
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.076"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(383..760)
                     /locus_tag="PC592_002704"
     CDS             complement(383..760)
                     /locus_tag="PC592_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4056655.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMEQKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFENHFKNLEEE"
     gene            complement(947..1916)
                     /locus_tag="PC592_002705"
                     /pseudo
     CDS             complement(947..1916)
                     /locus_tag="PC592_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(1950..2147)
                     /locus_tag="PC592_002706"
     CDS             complement(1950..2147)
                     /locus_tag="PC592_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HDF4056656.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            2633..3235
                     /locus_tag="PC592_002707"
     CDS             2633..3235
                     /locus_tag="PC592_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4056657.1"
                     /translation="MEVCILMGSPKKKGNTATILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKVLMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWSGKPVALITTCGYKPENGADIWENGMRRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYSILDNSIKVDNY"
     gene            complement(3511..4482)
                     /locus_tag="PC592_002708"
     CDS             complement(3511..4482)
                     /locus_tag="PC592_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDF4056658.1"
                     /translation="MKKVISIGEALIDFIPNQNGCKLKNVSGFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHSLHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSDQSCKNAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGIKVNAIDTTGAGDSYIGSFLYTLLCKQITLN
                     DIKEIKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEISEFIKNL"
     gene            complement(4508..5989)
                     /locus_tag="PC592_002709"
     CDS             complement(4508..5989)
                     /locus_tag="PC592_002709"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDF4056659.1"
                     /translation="MYKEPKYRTILESTKEELNDLRNISLNDKYKPIFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDVTHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNSIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMDKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSNKKGAIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDGKDILIFSPQGLEPKGFNYQNIYNVVYAIGNMDLDNLTFEIDIMK
                     EMEKGFDFYAPQTFIKDSQTILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELVKLRYDEISGQNTIKKNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKVENTVTLDRSNFKKVFSVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NNGEAVFTSRIFAKENSNQIKIYSDKIVCYKYTKFKLKQGIEL"
     gene            complement(6081..7511)
                     /locus_tag="PC592_002710"
     CDS             complement(6081..7511)
                     /locus_tag="PC592_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF4056660.1"
                     /translation="MSAKTIDYNKVSKQLLEYIGNEQNIKGVAHCATRLRIVLDSNNK
                     ANIKAIEELEGVKGVFIASNQLQVVFGAGIVNNVYKEFSKLSGFENMSLSDVKSESTQ
                     KQNKFQQAIKSLSDVFVQIIPGLLAAALLMGITGLLGQRGIFGELSIIEMYPQLAGLN
                     RFISIASTGIFTILPLLVVYSSTMRFGGSPVLGLILGAIMLHPELTNAYSVGNGSVVP
                     EIIDLFGLKVELVGFQGGIIVALMMGFVVAKLDKFFNSKIHDMLKLFLAPICTVIVAS
                     FLLFVIVGPLGRGLANIVTSSLLWITENLGIFGYMIFAGVQQVIVITGLHHVIGAVEA
                     QLIADTGTNFIMPLMSVALIGQGGAILGYLVLNWKDIKARQIGISSFASVLFGISEPA
                     IFGVTLKYKYPLIAGCIGGAIGGAYIYMTKVTALAFGATAVPGLAIVSTQGGGHVQYI
                     LAHLVTIVVAMITTILLGKLQKKSVN"
     gene            complement(7680..8666)
                     /locus_tag="PC592_002711"
     CDS             complement(7680..8666)
                     /locus_tag="PC592_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF4056661.1"
                     /translation="MKKITINDIAGLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIIAPCLDSFVKSKIMMAIDEELKELKYTSLIINTSRKI
                     RSEIDSISKLARLKVDGIILVGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIATKGYKNIVYLGVDESDISVGSNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQKSGEMLENENPDMIICATDTIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENESAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            complement(9149..10042)
                     /locus_tag="PC592_002712"
     CDS             complement(9149..10042)
                     /locus_tag="PC592_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4056662.1"
                     /translation="MAKLTLEHIKGNTYYIQLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLIPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVKTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKNLI
                     DINKKKMEEIIDNIKKVCCEPVMIDKVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKVLQ"
     gene            10191..11051
                     /locus_tag="PC592_002713"
     CDS             10191..11051
                     /locus_tag="PC592_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF4056663.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPDAFIIITDIHE
                     ALGNGFKKIE"
     gene            11320..11886
                     /locus_tag="PC592_002714"
     CDS             11320..11886
                     /locus_tag="PC592_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF4056664.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLIVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNARGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLENIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            11925..12506
                     /locus_tag="PC592_002715"
     CDS             11925..12506
                     /locus_tag="PC592_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF4056665.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTNGKVTNDGDFIFYNNLKHVSGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(12568..13485)
                     /locus_tag="PC592_002716"
     CDS             complement(12568..13485)
                     /locus_tag="PC592_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4056666.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     LISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVKYGKKQARKKSRSVNSL"
     gene            13615..15243
                     /locus_tag="PC592_002717"
     CDS             13615..15243
                     /locus_tag="PC592_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF4056667.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKVIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENVKRAVVIGGGFI
                     GLEIAENLSAMGIRVSVIDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIEG
                     ENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNKTLIADEYMLTNDKDI
                     YVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPEL
                     NAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQVM
                     GPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGEL
                     DSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGKN
                     SYMAQNRLKRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            15246..16193
                     /locus_tag="PC592_002718"
     CDS             15246..16193
                     /locus_tag="PC592_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDF4056668.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTIELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHQEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEACPVKAAKLTDNGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQINRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGVDKFIEMLLSDEVLERKEDILDAPLHLTGGAVC"
     gene            complement(16470..16733)
                     /locus_tag="PC592_002719"
     CDS             complement(16470..16733)
                     /locus_tag="PC592_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDF4056669.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQKNYD
                     YYGGFAKKNPCRMRVPNTGTWYIVVNQDGNSGIVNFSINTIQN"
     gene            complement(16832..17077)
                     /locus_tag="PC592_002720"
     CDS             complement(16832..17077)
                     /locus_tag="PC592_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056670.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTIYKDESSDSG
                     YYALLENEEERVVWDGEVVANNIFNKLWIVVNKVKTG"
BASE COUNT         5913 a         2589 c         2205 g         6556 t
ORIGIN      
        1 tgacagctaa gttactaata ataaagctta aaaatataaa aatcatttct tacttttagt
       61 ttacctataa taacaaaaga tagatttatg ttgtaataat taaaaatagt caaatatatt
      121 ttgatatggt taagtagaaa taatacttta gattaatgaa tattgataag ttataaaatt
      181 attttaaatt ttaaaaatca ctacttacta agataagtgg tatcatttaa cttgatactc
      241 cctattccaa ttgttttagg tattttacta attagaacct atttaatatt actttatgaa
      301 tagtgagtag ctgattaaat aataccattt atggtttgca gccatagatt aattaaattc
      361 ttaaagttct atcctaatat aattactctt cttctaaatt tttaaaatga ttttcaaata
      421 aatccaacat atctttatca acaacttcat catcatgtag tgctgaaatc aaactctgta
      481 aagaattgtc gtgtatatta cttaaaaaat cttttgtttc aacacttaaa tactccttat
      541 gtccaacaac tattgtataa tgagtgtatc tatctatttt ttctgcactt aaaaaatgtt
      601 ttttaacaag tcttgataaa agtgtcaatg tagttgtttg tttccaacca tatttttgtt
      661 ccatagcttc aatagtttct tttgatgtta ctgtatcatt tttttcccaa atgaacttca
      721 taacttttaa ttctgcttgt ggtatttttg aaattgtcat aaccttacgc ccctctcaaa
      781 cttttattaa attaatacta tcgcaatata gtttttaagt caaagatttt gtcgataata
      841 atatattcca attttttcca aataaatatt tcttatataa ttctataata aattacataa
      901 gaaatattca ttttacatca taaaattaaa aatataaata gtataattat ttagtcttat
      961 ctttaataaa caatccagta aatttataca tccaaagtgc attcataaac aacaatagac
     1021 ttgttgaaaa aaatactgtt ctaatgccta aatgtgctga tatttgtccc cctaaaaatg
     1081 ctcctgatga acagcctata tactgggcag atgcattata tccaaatatt ttccccacat
     1141 attcttctgg tgcaattttt taagcaagct gttcacagaa ggattaagcc ctgcaaccga
     1201 caaccctaat aaaaatctta acaacatcag ttgccatgca gtttttacaa aagcttgtgg
     1261 tatgaatata atcccagccc ataaaagtga aattaacaat actttttgag gtcctatctt
     1321 atctgacatt tttccaagtt tttgggctgc taataaattt gctaatcctg atgcagaaaa
     1381 tgtcaatcca gctattaaag ctacatttga tgcaaaattt gtgagctgtg atatatatat
     1441 ggttacaatt ggttctatag agtataaagc taattgagta acaaatgtag ttacaaaaat
     1501 agatgcaatt aaaaacttat ttggcaatat atctaattgt tttttaggtg tagaaattga
     1561 ttcttttatt tctttaggct taaaattatc tactacaaat aaaatagaga tgataaatga
     1621 tacaaacaac aatcctcctg ttataataaa tgtactttta agacctaaga ttgattctat
     1681 atatcctcct actgttggcc caattaagaa ccagtagttg atgcagttgc aagagtacct
     1741 aaagcccatc ctgaatgatt tttatctgtc tgtgttgcaa taagagtagt acatgcagta
     1801 gcataacctg taaaaactcc ttgaagtatt cttaatccta ataactgata aacattttga
     1861 acaaacgcca tggtaaatat aactattccc atcccaatac ttgcacgcaa aagcattgat
     1921 tttctcccat atttatcagc agctttccct caaattggtg aaaaaaatgc tgctactaca
     1981 aaagtacatc caaaaattat acctgaatac tgttgtatta aactaacatc agttaccccc
     2041 aattgtttaa tatataatgg aagtataggt gctatttggc tcatccctat agaactaaaa
     2101 aacataccta tccaacatac aaataaattt ctcttccaca attccatata gaattacacc
     2161 ccctgtattt taattttttc aataatacta taagtttatt aatttatgct attgattact
     2221 caatatattc atctcttctt ttataatatt gtttaggaaa ttcataacta gaaaataatg
     2281 gtatcgataa aaaataggag taaacatggt gcattttctt ctataaattt atagtcctca
     2341 tttaagtaca tattttttta cctaaaatat ttttaatata atcataaatt aaacaattat
     2401 aattctataa gatgatttta caataaattg ccatagttaa ctacacacat gtatgtaaaa
     2461 acatacctaa aatattttta attataaata catacagact tttatgacta aaataatttg
     2521 tttcaatttt attacaaata tacaaagtat attgttgtta acgtattccc atagtatcct
     2581 aaaactatat taagcactaa aaactatttt aaaatactgt ggaggtatca atatggaagt
     2641 atgcattctt atgggaagtc ctaagaaaaa aggcaatact gctactattt taaaaccttt
     2701 tattgaggaa ttagaaaact ataattcaaa tattgaagta atctggttat atgattgtaa
     2761 gatagagcca tgtattgctt gtaaaaaatg tcaggataac ttatttgatt ttggatgtta
     2821 ttgtaaagat gatgttcaga aaattttcaa gaaagttctt atgtgtgatt taattgtttt
     2881 tgctactcca atttattctt ggtactgcac ttctccaatg aaagcactac ttgatagatt
     2941 ggtgtatgga atgaataaat actatggtaa tgaaaaaggg cctgctctat ggtcaggaaa
     3001 accagtagca cttattacaa catgtggata taaacctgaa aatggtgctg atatttggga
     3061 aaatggtatg aggcgctatt gtaagcattc acagttaaaa tacataggaa tgcttgttga
     3121 acgtgattta ggtaaaccta attttatgaa taaagaaaaa gaagaacatt ctcgtcaatt
     3181 tgcaaaacaa atttattcta ttttagataa ttcaattaaa gtagataatt actaaatgtg
     3241 taatgccata agtaaagcat tgataatata aataaatcct acataattta cttatttaaa
     3301 ataaaatatg aagtctttaa aataaagtgt gtgttttcta aaaagtgaca ataattaaca
     3361 tgttttttat catttcaaca atgataaaga ggcttacctc tattttgaga tagcctcttt
     3421 attacttttt atatatcaat tattttcata gtaaccatca tcaaaaactc cttacatatt
     3481 acttctttca aatcctatta cttgttctta ctataaattt tttataaatt cggatatttc
     3541 ttcctttgtt gcatatgaac ttatcgcacc cttaatagtt gtactacgag ctgcataata
     3601 attagaaaac tctaaatact catttaacgt ttcttgtttt atttctttta tatcattcaa
     3661 tgttatttgt ttacacaata atgtgtataa aaatgaacct atataagaat cccctgctcc
     3721 tgttgtatct attgcattta ctttaatacc tttgcacata ccttttactt ttttagtata
     3781 ggcgtctact ccatcttttc cttttgtata taatactagt tcaacattcc ctacaaagag
     3841 tttatgtagt gatttttcta tatcattttc tcctgttata aattctaatt cttcatcaga
     3901 tatcttaaca atatgagcaa aaggtaaaaa ttctgatatt gcatttttac aagattgatc
     3961 actatcccat aaaggtaatc taatattagg gtcaaaactt attatactat tactttcaag
     4021 tgcatattct attgcttttt tatgtgctaa tttcattgga ctatctatta aatctactga
     4081 acaaaaatgt aggctatgac aattattaaa ccattctttt ttaacttcat cagcttctaa
     4141 aagcatatct gcacttggat ttctataaaa tgagaaatca cgattaccat cttcttttaa
     4201 tgatacaaaa gcaagtcctg tatttgcttt acttgttctc aatacataat cagtatttac
     4261 atttacttca tttaatacat ctattatata atcaccaaat gcatctttcc ctaacttaga
     4321 tataaaactt gattttcctc caagctttgc tacaacagca ctaacatttg ctggagctcc
     4381 tcctgctact cttctaaatc ctgatacatt ttttaattta caaccatttt gattaggtat
     4441 aaagtctatt aaagcttctc ctatactaat tacttttttc atcttttcta ccccttataa
     4501 tatgttttta taattcaata ccttgcttta atttgaattt agtatactta tagcatacta
     4561 ttttatcact ataaatcttt atttgattgg aattttcttt agcaaatatt ctactagtaa
     4621 atactgcttc tccattattt ataaaaattt ctaaaatact tctatctgct aatactttga
     4681 tgttagtatt ttcatcaata tttatatatt cttttctatt tgttccatac tcaacactga
     4741 aaactttttt aaagttgctt ctgtctaaag ttacagtgtt ttctacctta ttaaattcta
     4801 attttacacc ttcatcttgt gacgaaaata attccaatcc aaatttattg ctgtcaatat
     4861 tttttatatt aatattaagt tcatatacat tttcatcatt ttcgataata ttaatattct
     4921 tttttatagt attttgtcca cttatttcat catatcttaa tttaactaat tcatctacag
     4981 gcatttgtaa tagtttatta ttttttatat ttaattttct tggaacagtt agacaatgtg
     5041 cccatttatt tttatctgta gggtataaaa cttctcccat tccagcccat gcaaatagta
     5101 tagtttgtga gtcttttata aatgtttgtg gtgcataaaa atcaaatcct ttttccattt
     5161 ctttcattat atctatttca aatgttaaat tatctaaatc catattgcca atagcatata
     5221 ctacattata tatattttga taattaaatc ctttaggttc taatccttgt ggtgaaaata
     5281 ttaatatatc ttttccatct atattaatat aatctggaca ttcccacatg taaccaaaat
     5341 cttcatctat attttttaca tttaattcac ctttaaaatt ccaatctata gagtttttag
     5401 attcatatac aattatagct ccttttttat tacttgtttg agctccaagt agcataaagt
     5461 atttatcctt tcttttaaat acttttgggt ctcttacatg tcctgtatat ccttttggta
     5521 tttcacttac tattggatta ttttcatatt tagttatttt accatccttg tccattatag
     5581 ctaaattttg atatgcatat ctatcttctg cactatattt tatatttcct gtataataca
     5641 tatgcaattt tccatctact tctatcgaat tacctgaata tgctccatga gattcataac
     5701 tttcaattgg tattaatgct acatcttctc tattccaatt tacaaaatca tctgaactta
     5761 cataagccca atgcttcatc ccatgagtta catcatatgg ataccattga taaaatacat
     5821 ggtacttacc attataatat gctaatccat ttgggtcatt aagtagccca tgttgtggat
     5881 gtatatgaaa tattggttta tatttatcat ttaaagatat atttcttaaa tcatttaatt
     5941 cttcttttgt cgattctaat attgttctat atttaggctc tttgtacata tttttattcc
     6001 ttttctttta tagttttata taatcttaga agtcattagt atatatcact ttttatagtt
     6061 atttgattat ttataattta ttaattaact gattttttct gtaattttcc aagtaatatt
     6121 gttgttatca tagctacaac tattgttact aaatgtgcta atatatattg aacatgtcct
     6181 ccaccttgag tagacactat tgctaaccct ggtaccgctg ttgctccaaa tgccaatgct
     6241 gttacttttg tcatatatat gtatgcacca cctattgctc cacctataca ccctgctatt
     6301 aatggatatt tgtactttaa agtaactcca aatatggctg gttctgatat tccaaataat
     6361 actgaagcaa atgaagatat tcctatttga cgagctttta tatctttcca atttaatact
     6421 aagtatccta atatagctcc accttgacct attaacgcta ctgacataag aggcattata
     6481 aagttagttc ctgtatctgc tataagttgt gcttcaacag ctcctataac atggtgaagt
     6541 cctgttataa ctataacttg ctgtactcca gcaaatatca tatatccaaa tattcctaag
     6601 ttttcagtta tccataataa agaggatgtt actatatttg ctaagcctct tcccaatggg
     6661 ccaactataa caaatagtaa aaatgatgct actataactg tacatattgg tgctaagaat
     6721 aacttaagca tatcatgtat ttttgagtta aagaatttat ctagtttagc tactacaaac
     6781 cccatcataa gagcaactat tattcctcct tggaatccca ccaactcaac tttcaatcca
     6841 aataaatcta ttatttctgg tactacacta ccatttccta ctgagtatgc atttgtaagt
     6901 tctggatgaa gcattatagc tcctagtatc aaacctaata ctggacttcc tccaaatctc
     6961 atagttgaag aatatactac taacagtggc aatatagtaa atattcctgt tgatgctata
     7021 cttataaatc tattaagccc tgctaattga ggatacattt ctattattga caactctcca
     7081 aatattcccc tttgacctaa aagccctgta atacccatta acaatgctgc tgctaatagt
     7141 cctggtatta tctgcacaaa tacatctgat aaagatttga tagcttgttg gaatttgttt
     7201 tgtttttgag ttgattcaga tttaacatca cttaatgaca tattttcaaa tcctgatagt
     7261 ttactaaatt ctttataaac attatttact attcctgctc caaatactac ttgaagttga
     7321 ttagatgcta taaatactcc ttttactccc tctaattctt ctattgcctt tatatttgct
     7381 ttattattac tatctaaaac aattcttaat ctcgttgcac agtgtgctac accttttata
     7441 ttttgttcat ttcctatgta ctctaataat tgctttgata ctttgttata atcaattgtt
     7501 tttgcactca tctttatctc ctctcgattt aattaaaccg gtttcgaaac cggtttaatt
     7561 aaagactatc ataaatttat tttagatgca atatttcttt cgaaaaagtt ttcctaattt
     7621 ttggaattat agtttttcta ataaaaaaat acacattact aatatatgta atgtgtatct
     7681 taatttttat ttattgtact ttcaccttct attaattcaa atttaatctc ctttaatagt
     7741 ggttcttttc tttcttgtat taagtttact atcgtatttg ctgctacttt acctgcactt
     7801 tcattttcaa attttattgt tgtaagttta gggcttataa tagacaatac atcatatccc
     7861 ccaaatccag ctacagatat gtcttgtggt atatttttac ctctcttatt gatttccttc
     7921 attgttgcta ttgctatagt atcagttgca catattatca tatctggatt ttcattttct
     7981 agcatttctc cacttttttg tatagacgtt tcttggtcaa aatcagtata aaatactttt
     8041 gcatcatatc ctttatcttt taacccatta agtactccat tttttctatt tgaaccaact
     8101 gatatatcac tttcatctac gcctaaatat acaatgtttt tgtaaccttt agttgcaata
     8161 tattgcccca ttttatatcc tgctccataa tcatcattca ctatgctatt gataccatca
     8221 actttttgtc caactacaac tattggtata tctaactttt caatttcatt cttatgttct
     8281 ttagttattt cggtaccaac taatattatt ccatcaactt tcagtctagc taattttgat
     8341 atactatcta tttctgacct tatttttcta ctagtattaa taattagtga tgtatatttt
     8401 aattctttga gttcttcatc tattgccatc ataattttag attttacaaa agaatctaaa
     8461 cacggtgcta taataccaat aaagtatgtt tttttagctc tcaaactttg agcaaatgca
     8521 ttcggctcat atccatattc atctattatt gtctttattt tctctttagt agaatcactt
     8581 atatctttat tatttagata tctcgataca gtacttttag atactcctgc taatccagca
     8641 atatcattta ttgttatttt tttcataggt tatcaccttc tacatttgat atattttatt
     8701 tcattatatt atatatttaa aataaaatat agttatttat ctcttcaatg ctttttatac
     8761 attacttgta ctatctatac aacacttaga aaagtgtttt tttcactaag ttataatttt
     8821 tatttttgtt gttatattta attatatcta ctataaattg ataaatatct taaattattt
     8881 atcacataaa aaacttgtaa aaaaaaaata tatgaaaata aggctatgat tttcactgcc
     8941 atagccttat caataaatgc ttaatctcca tttaaaaaat aaattcttaa attataacat
     9001 agtattgcgg tcaaatattt attattctag aattatcagt aactttatat taattatttt
     9061 gccttattta tataaaatct atttttatat tattttttaa ataatagcat aactaaaata
     9121 gttttatcat ataatttgaa aatttcgact attgcaaaac ttttatcatc atcttaccac
     9181 catcaaatat gtattcaacc atattatttt catataaata agttatataa gaacgtattg
     9241 tactcccaac taatacatat tgattagcat caagcttgac attgtacaaa tcacacatct
     9301 tttcaataac tttatcaatc ataactggct cacaacaaac ctttttaata ttatctatta
     9361 tttcttccat cttcttctta ttaatatcaa tcagattttt tatatctgta gttttgacag
     9421 agtgacttgg aacaaagaag tctgcctcta acattctcaa tttttctagt gtcttaaact
     9481 gtgaatctat atccaataga aagaaaaaat gatatttagt aattatattc tctggtgtaa
     9541 gactatctgc aacaaacaaa acattatctg gagttttaac accaatcatt tcaaaataat
     9601 gacctggaag agaaatcgct tcaagttctg tatctacaat tttgccattt gaaggtataa
     9661 tataatcaac ttcactttcc tttgctaata aaaatttatt cttcagtgct ttacttggat
     9721 aaccaccata taaaaatgct gattctaata ttggattttc tgtaaaatat ccttcaattt
     9781 tagttgtggc aatcttgcat tttgtttgat tcttcagata tgcatttcct cctatatggt
     9841 ctgcatttga atgagtgttt attattaatt taggaatcaa attatgttct tctaataatc
     9901 ttaaaacttg tctagctgta tccttattgt ttccactatc aattaaaatt gcatctttac
     9961 catctacata tacacctact attgtaggga gttgaatata atatgtattt ccttttatat
    10021 gttctagagt taatttagcc attttataac ctccctttaa atttactttt aattatagca
    10081 ttaattttct gaaaattcca atcaaattat ttttataata tatttttatt tcttttatta
    10141 aaaattggaa aaactatata atatatatta taatctatat ataaggagtg atgttattga
    10201 aaaaagatag aataactttt tcagaaattt taatattaat tgtaggctgt atattaatgg
    10261 caatttctct taacttattt tttaacccac atgcaatcgc tgctggtggt ataacagggc
    10321 ttggagttgt tttaaattca ctattcggtg tagaactttg gattgtcaat ttacttttaa
    10381 atgttccatt attcatattt gcttacaaaa tactttcaaa gaaagattgt tttaaaacag
    10441 ttttaggaat aatttttctt accatagcac ttaagcttac tgcgaatatg gctacattag
    10501 atataacaaa cgatatgtat cttgcaatta tatctggttc tattttaatg ggagttggtc
    10561 aaggtcttat ttttagaata aatggctcta caggtggaac tgatttaatg gcactcctac
    10621 taaataaata ttttcctaca tttagtatac ctgttttaat gggtattgtt gactgtgttg
    10681 tagttgtttt atcaggtata gtaaatagac aggttgaaat tgcactctat tcaactgtgg
    10741 ctttatatat tttagtaaaa gttagtgatt tacttattga aggatttaat tattccaaat
    10801 cattcactat tatatctgac ctttcaaaag atataagtaa aaaaataatg gaagatttag
    10861 atagaggtgc aactattcta aaaggtgaag gtgcatatac tggagaaaat aaaaatgtac
    10921 ttttagtagt agttgaaaag aaagaagttg tcgaattaaa aaaattagta aaaaatgtcg
    10981 accctgatgc attcattata attacagata tacatgaggc tttaggtaac ggatttaaaa
    11041 aaatagaata attaacagac aaatagcaag tataattaca tatataaatg caacttttta
    11101 tatgtcgtat tacacttgct atttatatat tataaaacta caaaacaatt taaaccatat
    11161 agtggcaata tgtttaaatt ataaaatatt catgtagtta tataataaat aatttataaa
    11221 tatagccaaa ttggtctaaa tacatatata atatagctaa tatacttctt atacttgata
    11281 ccatcaataa aactaaaaat ataaaaagga gaacttaaaa tgagtgttag tttacaaaaa
    11341 ggacaaagag ttagcttagt aaaagacaat aatcctgtaa aaaatctaat tgtaggatta
    11401 ggatgggata tgaataaatt gggcaaaaaa aattacgacc tagatgcatt tgcaatagca
    11461 ttgactaacc aagataaaat gaacgctaga ggtgacttag tttattttgg aaatcttaaa
    11521 cacccttcca aagctattat acacactgga gataacttaa ctggaaaagg cgaaggtgat
    11581 gatgaacaaa taattgttaa tttagaaaac atacctgaat atgtacataa aatagttttt
    11641 ggagtttcta tatacaaagc taaaaaaaga gaccaggatt ttggtcaaat gaacaactct
    11701 tttataagac taattgattc aaattcaaaa caagaattat ttaaatacaa tcttcaagaa
    11761 gacttttctg gtaaagtaac agttttggca ggagaaattt atcgtagaaa tgaagaatgg
    11821 aaatttaatg ctttaggaat tggtcaaaat gaagagcttc gtgaattaat taatacatat
    11881 aagtaataat tacaataaaa atttacaatg aggagttgat ttaaatgggt ataactttag
    11941 caaaaggaca aaaagtaagc ttaacaaaaa gtaaccctgg cctaaaaaaa gtaatagtag
    12001 gactaggatg ggatattaat aaatatgatg gtggttttga tttcgattta gatgcttctg
    12061 catttttaac tggaactaat ggaaaagtaa caaatgatgg agattttata ttctataata
    12121 atttaaaaca tgtttctgga gctgttgaat atatgggtga taatagaaca ggtgttggtg
    12181 atggtgatga tgaacaaata aatgtagact tatctaagat accccaaaat attgctaaaa
    12241 tatcatttag tgttactata aatgaagcaa ttacaagaag gcaaaatttc ggacaagttg
    12301 aaaattcata tataagaata tacaacgaag aaactaatga ggaacttatt aaatatgaat
    12361 tgggtgaaga ttttagcata gaaacagcaa tagttgtagc agaactttat agacataacg
    12421 gagagtggaa atttaatgct ttaggttctg gatttgaaga tgggcttgca ggattatgta
    12481 aaaattttgg agttaatata ggctaatgta atatatctaa ataaaaataa gagtatatta
    12541 atatactctt atttttattt agatatatta taaactgttt acactcctac tcttctttct
    12601 agcttgtttt tttccatatt ttactgaaat atcaaagaat gctgaaatat tttctgtaaa
    12661 aaacttactt ctatgatatg caatatcaaa tgttctatgt aaattaatac cttcaatatc
    12721 acaagcccac aaaagatgct tttttaaata atcctcaata agtaactcag atataactgc
    12781 aatgccaaaa ttatctacaa ctgctcttaa tatagcttca gagttataac atgaccatct
    12841 aatattcatt gggattttta attcttttaa ttgtttttct aattgtgctc ttgtaccact
    12901 tcctaattca cgcataatta gtggttgatt tgaaagttct gaaactttta tagagtctct
    12961 tttgtagaac tcatgcttat gtgaacatat aagtacgaga ttatcattaa taatgctttt
    13021 tgtaacaata tccgggtgct taatttttcc ttctacaatt gcaatatcta attcactatt
    13081 aagtaatttt tttgcaatca atcttgtatc ttctacaaat acttcaggtt ctataagagg
    13141 atttaccttg tataattcta acattattgg gcttattaga catgtaccaa cagttactgt
    13201 tgcccctact cttatacgga tattttttgc acaatgcttc atacaatcat tcatttcttc
    13261 atttacagct aaaagatgcc tcccatatcc tagaagtttt tttcctgcct cagttaaata
    13321 taattttttt gaaattctat caaataactt aacaccatac tccttttcta tttctgaaat
    13381 agcttggcta actgatgact gggtaatata catatttctt gctacttcac tcattttacc
    13441 acattcagca accttaacaa atatctcaag actacgaatt gtcatattat cacaacctta
    13501 gcaaacatta gtaaatgctt atgattttat taatatttta gtattttaca aatacattgt
    13561 caagaagtat aattttatta tagagttata aagtagattg gagtgtgata tattgtgaaa
    13621 gtattaatta taggtggagt tgctgctgga acaaaaactg ctgcaaaaat aaaacgtgaa
    13681 atgggtgata attgttctgt tacaatacta aataaaggtg atgatatttc ttatgcaggt
    13741 tgtggtcttc catattacgt tggtaaggtc attgaagata aatcatcttt aatcgtaaat
    13801 acgcctgaaa gtttttctaa actaacagga gcagaagttc gttgtggagt tgaagttaca
    13861 tctattgata gaaatgcaaa acaagtaact ttgaaaacgc tttcaacagg agaaaaagaa
    13921 aatctaagct atgataaact tgtaattgct acaggggcgg atccaataaa accaccaata
    13981 cctggaatag atttacctgg agtattcttt atgcgtactc caaatgatgc tataaaacta
    14041 agagattcta ttgaaaatgt taaaagagct gttgttattg gtggaggttt cattggtctt
    14101 gaaattgctg aaaacctttc tgcaatgggt atacgtgtaa gtgttattga tatggctgaa
    14161 catgttatgc ctggatttga tactgatttt gctgaatatg ttgaaaatca tatggctgat
    14221 aaaggcataa tgatttttac aggtgaccag gttgtgggta ttgaaggtga aaataaagtt
    14281 gaaaaacttc gtactaaaaa tagagctatt aaaacagatt tagtagttat gtcagttgga
    14341 atccgtccta acacaggttt tctaaaagac acaggtttag aatttgctcc taataagaca
    14401 cttattgcag atgaatatat gcttacaaat gataaagata tatacgtagt tggagattgt
    14461 gcttttgtaa aaaattcttt aacaaataaa cctacatggt cacctatggg gtcatctgca
    14521 aatcatgaag gtagaatttg cgcacaaaat atatctggaa aatctaaaac ttacaatggt
    14581 gttcttggaa caacagtagt aaaattacct gagctcaatg caggaaaaac aggtctaagt
    14641 aaagaaatag ctgaaaaaga gggttataat gtttgctctg taaccatagc tactgatgat
    14701 aaagctcact attatccagg tgcatctaat tttattataa gaatggttgc tgaaaaaaat
    14761 actagaaaat tattaggtgt tcaagttatg ggacctggag cggttgataa aatagtagat
    14821 atcgctgcta ctgcaataac tttgggagct gacctttatt cattagaaag tatggacctt
    14881 gcatacgcac cacctttttc aactgctatt cacccttttg tagtggcagt aaatgtttta
    14941 caaaataaac ttaatggaga acttgatagt gttttacttg acgaaattga agattttgac
    15001 agttggacta aacttgatgt ttcaaaagct ccttctattc ctagtttgcg ttatattcct
    15061 gttggtgaaa ttaacggaga aattgaaggt cttgctaagg atgaaaaaat tcttcttata
    15121 tgtgctaaag gtaaaaatag ctacatggcg caaaatcgct taaaacgctt tggctataca
    15181 aatacgaaag ttcttgaagg tggaatacta ttttatccaa atcttaaggt aatggaggag
    15241 taaatatgag taatgttaca gcagaacaaa aaaaggaagt aaaaggtaga ggttttctac
    15301 caagcagaga tggagaacat tttgcagcac gtataataac tgtaaatggt gtaataaatg
    15361 catcacaagc aaaaaaaatt gcagaagctg ctgaaaaatt cggaaatggt caattagcat
    15421 ttactactag actaacaata gaattgcctg gtgtaaaatt tgaagatatt gaagctttaa
    15481 gtgaatttat cgctagcgaa aatttaataa caggtggaac tggctcaagg gttcgtcctg
    15541 ttgtagcttg taaaggtact gtttgtgttc atggtctagc tgatacacag gcacttgctg
    15601 ctgaaataca ccaagaattt tacaaaaatt ggtacgatgt aaaactacct cataaattta
    15661 aaattggtgt tggtggatgc cctaataatt gcattaaacc tgatttaaac gatcttggaa
    15721 ttgttggtca acgtgtacct gattatgact cagaactttg tgttggttgt aaaaaatgtg
    15781 ctgttgtaga agcctgtcct gttaaagcag ctaaattaac agataatggt aaacttgaaa
    15841 tagatagtaa tctatgtaat aactgtggta agtgtataga aagttgtaat tttgatagta
    15901 ttgaagaaaa agaatctggt tataaagtct atataggagg gaaatgggga aaatcagttc
    15961 gtcctggaac acaaattaat agattatttt caaaagaaga acttatgact ttaattgaaa
    16021 aagcaattct tttatttaga gagcagggta acacaggtga acgttttgga ataactatcg
    16081 atagaatcgg tgttgataaa tttatagaaa tgcttttatc agatgaagtt ttggaaagaa
    16141 aagaagacat acttgatgct cctttacacc ttacaggtgg agctgtatgc taacaataaa
    16201 tattttagtt gtataaatat cattaacata ttgaaaaaat tttagttaag aataatcaaa
    16261 attcttatga taaatgaggc tatctcaaaa cacagataag cctctttttc attgttgaaa
    16321 tgataaagta tatttgagta taaaaaagag tgtctcataa actataaaat tcattttgag
    16381 gcacccaaat tattttataa taattgctta ttaattttat tttaaatata taaaatgcac
    16441 aaaaagtaag aatatcttat attctaaaat taattttgaa ttgtattgat tgaaaagttt
    16501 actattccac tatttccatc ttgatttact actatatacc atgttcctgt attaggaact
    16561 ctcattctac atggattttt ctttgcaaat ccaccatagt aatcataatt tttttgattt
    16621 ttaaatttca cataatttat atggtctaac aatattacat tggcttgttt ctctaaattt
    16681 acctctacaa tatccccttt ttttaggttc atcttactat aactatattc cattgaatta
    16741 ctcctccagt atcgaataat ctttgttatt tactcatctt aaatatgtaa aaattcattt
    16801 aaaatattac aaatactata caattggact attatccagt tttaacctta tttactacaa
    16861 tccaaagttt attaaaaata ttattagcaa cgacttcccc atcccataca actctttctt
    16921 cttcattttc taataaagca tagtacccag agtcagaact ttcatcttta tagattgtaa
    16981 cataaaactc ttcatcacta tattcaggta tatttttaaa gtcttcagat attttacatg
    17041 ttaatatata tccttctagt tcttcatcta taaacaaagc aattcctcca atctctatat
    17101 ttttactaat tataccatat tatgtcataa actttttatt tcgttgtaaa attctatttt
    17161 ttctttactt tataaacaat ttatatattt ttttagtttt ttactttaca ttacactaat
    17221 taattctttt gttttcttat atattccttt ataattcata aat
//
LOCUS       DAMKOJ010000071        17042 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.077, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000071 DAMKOJ010000000
VERSION     DAMKOJ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17042
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.077"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..860
                     /locus_tag="PC592_002721"
     CDS             <1..860
                     /locus_tag="PC592_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase dimerization domain-containing
                     protein"
                     /protein_id="HDF4056671.1"
                     /translation="NAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNV
                     GANYLREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVA
                     QGAAMMTETEMEYKVTDGIYDYIPNQCLTDLVYNNMVFVGCPKTTPEEEEFAKKLCDT
                     LTREERLGVATSFQNDKSIVESYIHKGIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMA
                     AWPVGIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSL
                     DGQKFKPLV"
     gene            895..1119
                     /locus_tag="PC592_002722"
     CDS             895..1119
                     /locus_tag="PC592_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF4056672.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(1442..1840)
                     /locus_tag="PC592_002723"
     CDS             complement(1442..1840)
                     /locus_tag="PC592_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF4056673.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKNDEE
                     KKKFFHKFSIVVWTIWLIPYFIGMFIGMAG"
     gene            complement(1843..2244)
                     /locus_tag="PC592_002724"
     CDS             complement(1843..2244)
                     /locus_tag="PC592_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF4056674.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDEKELSDLVKNLRTILAKVKER"
     gene            2605..3591
                     /locus_tag="PC592_002725"
     CDS             2605..3591
                     /locus_tag="PC592_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056675.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYNQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRVICKLGTITNCIPSFWVALVLILVFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLVLSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEAAI"
     gene            3575..4486
                     /locus_tag="PC592_002726"
     CDS             3575..4486
                     /locus_tag="PC592_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056676.1"
                     /translation="MKPQYSDFEIVGENYILVAKDEHVETKKNLFRKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASEFVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            4599..6167
                     /locus_tag="PC592_002727"
     CDS             4599..6167
                     /locus_tag="PC592_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4056677.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADKPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGILPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQVTPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNHTIDKI
                     LQKARETENKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            6242..7267
                     /locus_tag="PC592_002728"
     CDS             6242..7267
                     /locus_tag="PC592_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056678.1"
                     /translation="MEHLLEVNNLSVNFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSNLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLHPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPKIDVPVRVNC
                     GRVISNE"
     gene            7260..8204
                     /locus_tag="PC592_002729"
     CDS             7260..8204
                     /locus_tag="PC592_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056679.1"
                     /translation="MNREKMLEIKNLKQYFHLDKNTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIVRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGIYKNKTDRMNKVYEMLNLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRTRIEYNSN
                     VYDCSNEKSLSWIEVSDGHFVYSSKADINKYQQNLKVV"
     gene            8564..11221
                     /locus_tag="PC592_002730"
     CDS             8564..11221
                     /locus_tag="PC592_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4056680.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQNELLGIKKGTTVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAVLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERIELIKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLKYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHRIEYFVFTSLG
                     EEEVINYNDINIINAVNTNINKSVEMNITDASLFNNVKFKNMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGNCNAISFDL
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVMVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMNRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVALINEQRINIRGIDY
                     ISKKDIDKDKSINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKMLNYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            11435..12064
                     /locus_tag="PC592_002731"
     CDS             11435..12064
                     /locus_tag="PC592_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056681.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAIIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEIMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEQYNSEEVIDTAFRFNHWQY"
     gene            12182..12508
                     /locus_tag="PC592_002732"
     CDS             12182..12508
                     /locus_tag="PC592_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4056682.1"
                     /translation="MNILLVCANGASTGVLVEKMKNFCSEHEKLKTKTINIEATSFEN
                     LKSYIQANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            12524..13813
                     /locus_tag="PC592_002733"
     CDS             12524..13813
                     /locus_tag="PC592_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4056683.1"
                     /translation="MEALQNNLRKFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVIAQLVVCGQVIDGALDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVLGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSLNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATALDDDSFDF"
     gene            13837..14166
                     /locus_tag="PC592_002734"
     CDS             13837..14166
                     /locus_tag="PC592_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF4056684.1"
                     /translation="MVPEIEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            14314..15642
                     /locus_tag="PC592_002735"
     CDS             14314..15642
                     /locus_tag="PC592_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF4056685.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKNPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLESRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TKERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGEIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPELN"
     gene            16060..16920
                     /locus_tag="PC592_002736"
     CDS             16060..16920
                     /locus_tag="PC592_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF4056686.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCN
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
BASE COUNT         6777 a         1884 c         2988 g         5393 t
ORIGIN      
        1 taaatgcacc ttggagaggt ggaagtctag caaacttatc tgtaaaattt aaatttaaag
       61 gtataacagc ccatgcagct caagctcctc ataatggtag aagcgcactt gatgctgttg
      121 aaattatgaa tgttggagct aattatttga gagagcatgt tattgactct ataagaatgc
      181 actatgttat aactaatggt ggtggaagac ctaatgtagt tcctggcttt gctgaaagtt
      241 ggtactttat tagaggaaaa aaagcaaagg acgcagaaca cgttcttgat agattaataa
      301 aagtagctca aggagcagca atgatgacag aaactgaaat ggagtataag gttacagatg
      361 gaatatatga ttatatacca aaccaatgtt tgactgattt ggtttataat aatatggttt
      421 ttgttggatg tcctaaaact actcctgaag aagaagaatt tgcaaaaaaa ttatgtgata
      481 ctcttactag agaagaaaga ttaggtgtag caacatcatt ccaaaatgat aaatccattg
      541 tagaaagcta tatacacaaa ggtatagttg atggagacaa agataaagga ctagctggtt
      601 ctactgatgt tggagatgta agttatgtta taccagtggc tcaatttgca atggcagcat
      661 ggcctgttgg aattgcaagt catacatggc agtcatgttc atcagcaggt tcaaatatag
      721 gattttctgc tatgataaat tcagctaaag tattggcttg tagtgcctat gatgtattta
      781 tggatactaa aattattgat gaagcaaaaa tcgaatttga taaatcatta gatggacaaa
      841 aatttaaacc attggtataa ttttggtaat aaaatatttc tggggggaat agctatgaga
      901 gaaaaagttg aaaaagtgct tgaagaaaag ataaaaccag tattgcaaag agatggtgga
      961 gatgtagagc ttatagatgt aaatgaaaat ggtgtagttt tagttagact acaaggagca
     1021 tgtagtgggt gtccaggagc gactatgaca atcaaagcta ttattgaaaa tgttttggtg
     1081 agtgaagttc caggagtaac tcaagtatta ggtgtttaac agttagagtt tattaaatat
     1141 atgttataca taaatattta ataaagaagt atgaaaaaaa tagtgaaacg ttatatataa
     1201 aaatatgaaa aagataataa aacattatag aaacaattaa atattccata tagatatgaa
     1261 aaattgtgag aaaataataa aatattatag gaataattaa atattctata ttaggtatga
     1321 agaaatatga aagacataat gaagtattat agataaatat gtaaaagtgt gaaagaaagg
     1381 tgtagataaa tttgttttat acaaatttac ctaccatatt tcttacacac tttttatttt
     1441 gctatccagc cataccaatg aacataccta taaagtatgg aattaaccat atagtccata
     1501 caactatact aaacttatga aagaattttt tcttctcctc atcatttttg tataggacaa
     1561 aagtagccca acttgcatga aaaagcataa gcacaattgc aagaagacct gtaatactat
     1621 gaaggttttg tgataaagcg gattttactt caaaagtatg gctgttggct atgttactca
     1681 ttgtaaatgt tcctaaagtg tcaaatataa aaccaagcca aaatataatt acatgtttct
     1741 ttttcaaaat tttagccttt ctttctccaa atacacctat agtgtagaaa attaaagctg
     1801 atgttataaa tactattgca agtattaatt tataattcat aattatctct cctttacttt
     1861 tgccaatata gttctaagat tttttactaa gtcactcaat tctttttcat cacaattttt
     1921 aaaaatatca tcaaaacttt cttgcatctt aattttaaaa tttgttgcaa attcaaatcc
     1981 tgttgttgta aacttaacgt atgtatttct tttatcatta gatttcttga atttttctat
     2041 atatccaatc tgttctaatc tgctgattat gcctgaaacc gtacctttag ccaaagacat
     2101 ttcatcacaa agttgtgata ttgtaagttc ctgattatga gctattagct ttataactat
     2161 aatctgttgg tgtgttaatc cattttcttt aaaattttct tccactgtgt acatagtttt
     2221 agaataaagt tcttttaaga gcatggctat tctaaaacag tcataattag ttttcaataa
     2281 aatcacctct taaatggttt gcatacaaac taaatataat atacttttat tatatagtca
     2341 acctaaaatt ttataatttc atataaaata atgaagaata gaacataaaa attttatttt
     2401 agatataaat aaaataattt gatgaaattt taacaatttt taaaaagttt gtttacacag
     2461 ttaataaatg atgctaaaat taactcatag ataaatattg aaaatttaaa tttgtttaat
     2521 gataatagaa ccacgaaggt tttaacgtta ctttacgttt gcttttatgt ggtttttttt
     2581 attgcaacaa aggggggttg gggtttgtta aaggatatac tgaaaaagtt gttgcagttt
     2641 attttagtaa tgtttttatt atcttttatt gttttttaca tggcaagact tgctccagga
     2701 gacccattaa tctcttatta tggggatgga gtagaaagaa tgagtacaca agaaaaagaa
     2761 aatgctatga aaaaacttgg tttagatgaa ccaatataca atcagtatat aaagtggatt
     2821 tcgaatgcat caaaaggaga atttggaatt tcatttaaat ataaacaaaa tgttacttct
     2881 gttataaatg atgtctatat aaacactata atattaggtg gttcaggata tatacttacc
     2941 tttgtactag ccttattgtt aggaatattt tgtacactac atgaagataa gctcattgat
     3001 agagtcatat gtaaattagg aacaataacc aactgtattc catcattttg ggttgcttta
     3061 gtactcatac ttgtatttag tataaactta agtatacttc caagtagtgg cgcttattca
     3121 atgggagaag aatccagtat attaagtaga atatcacatt taattttacc tcttacagta
     3181 cttgtattga gccatttatg gtattacaca tatatgataa gaaataaatt actagaagaa
     3241 ataagagaag attatgtact tctatgtaaa gcaaaggggt taaataatag aactattgtt
     3301 tttaagcatt gcctgagaaa tataatgcca tcatatatca gtataatggc tatttcgata
     3361 cctcatatac taggcggaac ttatgtagtt gaaaaagttt tttcttatcc tgggctagga
     3421 acactttgtt ttgaaagtgc aaagtatcat gattataata tgttattagt tttatgctta
     3481 ataacagggg ctttagtagt atttgggaat atgttagctc aaattataaa caataaaata
     3541 gaccctagaa tgaaatatga tagaggtgat actaatgaag ccgcaatata gtgattttga
     3601 aattgtagga gaaaattata ttttagtagc aaaagatgaa cacgtagaaa caaaaaaaaa
     3661 cttatttaga aaaattaaag aattaccata tatatcaatt attattttat caattatagt
     3721 aattggaagt gtattctcat cttttataat gacacatgag ccgacatata tggatttagc
     3781 aagctctaat ttagctccaa ataaaacttt tttatttgga acagactcaa tgggtagaga
     3841 tatatattct atgatatggt atggaggaaa aatatcttta tttataggat tattttccac
     3901 tgtaatatca actgttatag gaattgttta tggtagtata agtggttcag catctgaatt
     3961 tgtagatgat gcaatgatga gatttacaga aatcatactt agtatacctt caatattaat
     4021 tataatattt gtacaagcta tacttggaaa ttcaaatcca gtatctatgt ctatagtaat
     4081 aggtataaca agttggatga atatatctaa gatagtgaga acagaggtta gacaaataag
     4141 aaatagtgaa tacatactag cagctaagag tatgggagga ggattcttct atgtattaaa
     4201 gcaacattta cttccaaatt ttgtggcatc aataatgttc atggttgtaa caaatatagg
     4261 tgcagctatt ggtactgaat caacacttag ttttttagga attggtttac caatagaaat
     4321 tgtttcttgg ggaagtatgt tatctttatc agaggaagca ttactttcaa acagatggtg
     4381 gattatactg attccgggta tatttttggt taccacattg gtgtgtataa caaatatagg
     4441 taattacata agaaagaata ataataaaaa atctagtaat ttataaatca gcatttgagt
     4501 ataaaataag caaatactga ggtatttgaa atatctattt aaataaatgg ggtcaaagct
     4561 ttgaaaaata ttttataaaa agcaaaaggg ggagcatcat gaaattaaag aagttaaaag
     4621 ttttaagttt agtaatgata cttagtctaa tggcaggttg ttctagtgga ggagacaaag
     4681 ataagaaagc agataagcct aaagatggaa aggtacttgt ttatggaagt aatgactata
     4741 caagtataaa tcctgcacta tatgaacatg gagaaataaa ttcattaata tttaatggat
     4801 tgacagctca tgatgaaaac aataaggtgg ttccttgtct agcaaaagat tggaaatttg
     4861 atgaggcaac aaatacatat acttttaatt taagagatga tgttaagtgg catgatggag
     4921 agaaatttac agcaaatgat gttaagttta caatagaaac tataatgaat ccagacaatg
     4981 cttctgagat agcatcaaat tatgaagata taacaaaaat tgatgtagtt aatgataaca
     5041 ctataaaaat tactttaaaa gctccaaata cagcaatgct tgattattta acagtaggaa
     5101 tattaccaaa acatgcttta gaagggaagg atatagctac tgatgaattt aatcaaaagc
     5161 caataggcac tggtccattt aaacttgaaa aatgggacaa aggtcaaagt ataacacttg
     5221 ttaagaatag tgattatttt gtaaaagaac caggattaga taaagtagtc tttaagattg
     5281 ttccagatga taaggctaag gcaatgcaat taaaatcagg ggaattagac ttagctcaag
     5341 taacacctaa agatatgtct aactttgaaa aagacgaaaa gaattttaaa gtaaatataa
     5401 tgaaaacagc cgattataga ggtatattat acaattttaa ttctaaattc tttaaagata
     5461 aaaaagctaa aggattgcca aatgctttaa gttatgcaat agatagaaaa gcaatcgttg
     5521 atagcgtatt attaggacat ggtgttccag catattcacc tttacaaatg ggaccatata
     5581 ataatcctga tatagaaaag tttgaatata atccagaaaa agctaaacaa gaaattgaaa
     5641 agctaggttg gaaattaggt tctgatggaa tatatgaaaa agaaggtact aagttagctt
     5701 ttgagataac agcaggtgag agtgaccaag ttagagttga tatggctaag atatgtgcac
     5761 aacagttaaa agaaattggt gttgatgcta aagctgtagt tgtaactgaa acagactggg
     5821 ctaatcaaga tgctcattta ataggttggg gaagtccatt tgacccagat gaccatacat
     5881 ataaagtatt tggaacagat aaaggtgcaa attacagtgc ttactctaat catactatag
     5941 ataaaattct tcaaaaagca agagaaacag aaaataaaga tgaaaagtta aagttatata
     6001 aacaattcca agtagaaatg actaaggata tgccttacac atttattgct tatatagatg
     6061 caatatatgt tggaaaacca aatatcaaag gattaacacc tgatacagtt ttaggtcatc
     6121 atggtgtagg tatattctgg aatatagctg actggacaat tgaatagtat tgaaattaat
     6181 tagaaacctt agggataaaa gtatatccct aaggtttgaa tagcataggg gttgatggtt
     6241 tttggaacat ttattggagg ttaataatct atctgtaaat tttaaagtag aagaaggaga
     6301 agttcaggct gtaagaaacg tgtcttttaa tctgaaaaag ggtgagacat tagctatagt
     6361 tggagaatct ggttgtggga aatctgtact atgcaagagt ttgatgagga tactcccata
     6421 caatggatat attaaaaatg gagaggtttt acttaaatca agtaatttgg ttaagaagtc
     6481 tgaaaaagag atggaagata taagagggaa aaatatatca atgatatttc aagaccctat
     6541 gacatctctc aatccaacta tatcaatagg aaagcaaatt gcagaagctg taatcattca
     6601 tcaaggtata agtaaaagtg aagcaaaaaa gagggccata gagcttattg aattggttgg
     6661 aatagataat cctgagaaaa gatttaaaca atttccacat catttttcag gtggaatgag
     6721 acaacgtata gtaatagcta tagcacttgc ttgtaatcca gatgtattga ttgctgatga
     6781 acctacaacc gctttagatg taactataca agctcaaata attgatttaa taaaggattt
     6841 acaacataaa ataggtttgt caataatatt tataactcat gatttaggag tagttgcaac
     6901 tattgctgat agaatagcag ttatgtatgc aggaaagatt gtggaaatag gaactgtgga
     6961 ggatatattt tatgacccta gacatccata tacttggggg ctgttaggtt cattacctac
     7021 tttagattcg caggatgact atttgtataa tatacctgga atgcctccaa acttattgca
     7081 ccctccaaaa ggagatgctt ttgcaataag gaataaaaat gcacttaaaa tagattatga
     7141 aaaagagccg ccaatgttta aaatcaatga tacacatagt gcagcaactt ggttattaca
     7201 tccagatgca cctaaaatag atgtaccagt tagagtaaat tgtggaaggg tgatttctaa
     7261 tgaatagaga aaaaatgctg gaaataaaaa acttaaagca atattttcat ttggataaaa
     7321 atactactgt aaaagcagtt gatgatataa gttttgatat atataagggt gaaatatttg
     7381 gattggtagg agagtcgggt tcaggcaaat ctacaactgg taagactata gtaagactac
     7441 atgaatctac tggtggagaa gtaatttaca aaggaaattg tatatccgat aagaagacat
     7501 acaaatttat aaaaaaagat gtaaacaaaa gtatgcagat tatttttcaa gattctactt
     7561 catcattaaa tccacgtatg acaattgcag atataatttc agagccacta aaaattcaag
     7621 gtatctataa aaataaaaca gatagaatga ataaagtata tgagatgcta aatctagtag
     7681 gacttgatag aagttatgca aataagtatc catctgattt ttcgggtgga caaagacagc
     7741 gtattggcat agcacgagct ctttcagtag acccagaatt tataatagct gatgaaccta
     7801 tagcttcttt ggatgtgtct atacaagcac aaatagtaaa tttatttaag aagttacaac
     7861 aagaaaagaa tttgacttgt ttatttatag cccatgattt atctatggtg agacatatta
     7921 gtgaccgtat aggagttatg tataatggaa aattagtaga actggcagat tcaaatgaat
     7981 tgtataataa tcccattcat ccatatacaa aatcactact ttctgcaatt cctgttcctg
     8041 accctagata tgctaagtca agaactagaa tagagtataa ttctaatgtg tatgattgct
     8101 caaatgaaaa gtcactaagt tggattgagg tttcagatgg acattttgta tattcttcta
     8161 aagctgacat aaataaatat caacaaaatt taaaagttgt ttagtataaa aaaacttgaa
     8221 catgtattta tttgaaatac aaactaaaac cctatttttg gataaatttt aaaactactc
     8281 caagataggg ttttttattt acacttttca aatataataa attcaaatat aataaaatta
     8341 aaaacaagta aagtatattg ttaagaaagt accataaaat taaaaaatag tattttagaa
     8401 aaaattatca ataaccttat tttttctaca ataattttat ataatttaaa ataagacaag
     8461 tttgataaat tataatctta gttaaagaat aagagtttat taaaaaacaa agtgagtata
     8521 aggattttag ttaacaaaat attataatgt aggggagctt gtaatgatat ataaaaaaga
     8581 taaagtaatg aaagttttag aatcatcata tagggaaaat gaaaaaggga ttacagctaa
     8641 ccaattatca gaaaagacag gaattgcaag aaacaatata agtacatatt taaaccagct
     8701 attcaatgag ggtatggtta caaagataaa aggaagacct gtgtattata tccctgcaaa
     8761 tcttaacctt aacaagaatg aattgcttga tacacaaaat gagttgcttg gcataaaaaa
     8821 aggaacaaca gtagaaaaca agataaaaaa agatagtttt gaaacactaa taggtaaaga
     8881 acatagttta agacctataa tagaaaaatg taaggttgca gtgctttatc ctacaaatgg
     8941 acttcatacc attatctatg gagaaacagg agtaggaaag agtatgattg ctagatatat
     9001 gtatgactat tctatagata gtggaattag gaaaaataaa gctcctttcg taacatttaa
     9061 ttgtgctgat tatgctaata atgcacaatt acttatggga catatctttg gagtagaaca
     9121 aggtgcttat acaggtgcag aatcttccag aaaaggactt ttggaaattg caaatggggg
     9181 tatattattt ttagatgaaa ttcatagatt accagcagaa ggtcaagaaa tgttgtttac
     9241 ttttatagat aaaggaacat ttaaaagact aggagatgca acgaaagaaa gagagtctaa
     9301 ggtattaata atatgtgcta ccacagaaaa tccgacatca acactattag atacattcaa
     9361 tagaagaata ccaatgaaaa tagaaatacc atcactgaga gataggacaa tgattgaaag
     9421 aatagagtta atcaaaaatt ttttcaaaga agaatcaaaa agcatttcta tttcaataaa
     9481 agtacataaa gaaataatta aatcactatt actttatgat tgtaaaaata atgtaggtca
     9541 acttcaaaat gatataaaat tagctgttgc aaatggatac ttaaagtata aaagagataa
     9601 taaagaacca gtttatatag agaaaaaata ttttgataaa tctataaatg aagtgagtga
     9661 tgattataga gagaagtcta ttaaagcaga tgaagttata acacatagaa tagaatattt
     9721 tgtgtttacg tcattaggag aagaagaagt tattaattac aatgatataa atattattaa
     9781 tgcagtaaat actaatatta ataagtctgt agaaatgaat ataacagatg cttctttatt
     9841 taataatgtt aagtttaaaa acatgtgtga atcaataaga caaattatta aagaagatga
     9901 agaaatagat ataagtgaat caatatttaa gtcaatggca atttatataa aaagcgtatt
     9961 ggataaaagt agctctacaa acaacataga tttgaatcaa attagaagaa ataatagaag
    10021 tgaatttaaa acagcattaa aaatagttgg aataattgaa aatgaatttg atttattttt
    10081 atctatagaa actgtagcat atattacatt attcatagta caagctaaac aagatgagca
    10141 aaataaaata gtgaataaca ttaatattat agttgctatg catggagaaa ctacagcaag
    10201 tagtatggtc aaagcagttg gtgatattat tggaaattgc aatgctattt cttttgattt
    10261 gaagttagat aaaagctatg atgaagttat tgtagatttt aaaaatttaa ttaataatat
    10321 agacaacaag gatgtactac tatttacaga tatggggtca ttaaactcct ttgatgaaat
    10381 tataaagaaa gaaaaaaagt gtggagtaat ggtaattcct atggttacaa cattaactgt
    10441 gttagaagca gttcagaaag ctaatatggg actaccttta aatgatgtat acaactctat
    10501 tactaacacg agaaagtact attttggaac taatgaaatt caaaataaag aaaatctgtc
    10561 taaaacaatt attatagcat cacacgtttc agaaggtgta gataataaaa caagaaaaat
    10621 attagaagaa aagatgaata ggtatttaga tggaatagat attatatctg tcccatataa
    10681 aacagaaaaa gacttaagtt taaatatcac aaaacttaaa gaaagtagta atattgtagc
    10741 attaatcaat gaacaaagaa ttaatattag aggaattgac tatattagca aaaaagatat
    10801 agataaggat aaaagtatca ataaattaaa aaatattata aagataagta taggttatga
    10861 tgatgtagtt gaaggtctaa agacatcctt aaaaagctct aattataata ggatatttaa
    10921 agatataaaa tatgtgtctg acgaattgtt tttagtattt aacatagaaa agaaatatga
    10981 taaagtaatt ggacttatga tgcatttagc ttttatggta gatggattga ttggaaatac
    11041 tagagaaatt gaaaagcttg ataaagaaaa aatgcttaat tatcacaaga gcttaagtaa
    11101 aataaaagat atagtatctc aattagataa aaaatataat atagaaatta atgaaaaaga
    11161 gtgttatcaa atattgttaa tattagaata tgcagaaata atcgaaaaag attaccaatg
    11221 agtataaaaa cttatttggt aattttttta gtctaaaata atattaatat tagacacata
    11281 tgaatatact tagacaaagt atctaagttt ttgtgctaaa aatgactgaa ataacaccgt
    11341 tttaaagtgt ctaaaaaaat tggcataata cttgcttata ttactaaatt agtaatataa
    11401 ataattaaaa tttaaataaa aaggagtaaa taatatgcaa gataaaatat taagagataa
    11461 aaaggcaaat gacccatggg caagaatgac tacaagaaac ggatttagtg cagacgaaat
    11521 aatatcatca tttcaaaaag ctataagaag aaatatggtg gaagaagctt gtgaatttgc
    11581 ttatgaacta tatatatcat caccagaatt agaagataag ctatggagaa gaatacttac
    11641 aatatcagtt gaagatatag gaatggggga cccatcagct ataataatca taaataattt
    11701 aaatcaagta agaaaggaat attcatatgc agatggagat agacctctat ttttcataca
    11761 tgcaataaga tatctttgtg catgtgagaa agatagatca agtgacttat taaaaaatat
    11821 aattataaaa ggatttgcaa tgggtaaagt tccagaaatt atggacgtgg cacttgataa
    11881 acatacatat agaggattag aaatgggaag ggattcattc cacttcttaa atgaagctag
    11941 catagtaata ccagaaaaag aagtagataa tgattataaa gaaagatact taaaaatatt
    12001 agaacaatat aattcagaag aagttataga tacagctttc agatttaatc attggcagta
    12061 ttaagaatta gagtaaatat taataagaat taaaataaaa attaataaga attagagtaa
    12121 taattaatta ataaaaaatt agaaaataaa agaggttaga tattgcagga gggtaattat
    12181 tatgaatatt ttattggtat gtgcaaatgg agcttcaaca ggggtgcttg tggaaaagat
    12241 gaaaaatttt tgtagtgagc atgaaaagtt aaaaactaaa actataaata tagaggcaac
    12301 atcatttgaa aatctaaaat catacattca agctaatgat acagatgtag tacttgtagc
    12361 accacaaatt aggttcaagg aagatgatgt agttgaagct tgtaaaaatt acaaaatagc
    12421 agttggttta atagatacta agcattatgg tcgtatggat gctccttctg ttatgaagtc
    12481 ggcaatcgaa ttatataaaa atagataatt ggggggaata aatatggaag cacttcaaaa
    12541 taatttaaga aaatttcttc ttccaatagc acaaaagatt gaaaaacaaa ggcatcttca
    12601 agctataaaa gaaggtatga taagtattac cccaataata attgttggtt ctttaagtat
    12661 gttatttatg gcattaaaca atatgttacc tgaaggaagt gcaaaaacat tattatctga
    12721 aaatatggat acattactta tccctaataa atttactatg agtttattat ccatatattc
    12781 agcatttttt atagctcagg cactagctaa aaaatataat cttaatcatg tagaaatagg
    12841 tatgacagca gttatagcac aacttgttgt atgtggacaa gtaatagatg gtgcattgga
    12901 tacaagttat ttagatgcac aaggtttatt tgtaagtata ttagtagcac ttttagtagt
    12961 tgatattact aaatttatga atgataaaaa tctcgtaatt agatttccaa aagaagtacc
    13021 tagtgtagta aataaaagct ttagaaactt aacaccaatg atagtatgta taatgttatt
    13081 tacagcaata gcagcaataa ctaaaaatgt cttaggtcaa ccgttaccag ctattataat
    13141 gaatttctta gcaccagcta taagcagtgt agataatgtt tttgcagtaa ctataatact
    13201 atttataact caattattat ggttctttgg acttcatgga gcagcaataa cttcaagtat
    13261 atggatgcca atagcagcta catatatggc agaaaatgca acactaatag ccgcaggagg
    13321 agacccaaaa tatgtattta caataggttt ttactatggt ttcttgcaag taactggttc
    13381 gggaataact ttagggttag tgtaccttat gtcaagaagc aagtgtaaga gtttaaatag
    13441 tatgggaaaa gttgtgattt taccatcatt atttggaata aatgagccag taatatttgg
    13501 aacaccaata gttatgaacc catatatgtt tgtaccattt gtatttggac ctgtattggt
    13561 tggagcactt aactttatgg cattaaaggt aggattagta ggattaccta ttgcagaacc
    13621 accaggcttt ttacctccag gggttgcagc atttttaatg acattagatt ggaaggcaat
    13681 tgtattagta tttgcaagta taatacttat gaccttgata tattatccat tctttaagat
    13741 aatggagaag gaagaattaa ataaaaatgc agaattagct acagcattag atgatgatag
    13801 ctttgatttt taacaagtca ttagaaggag aaggatatgg tacctgaaat agaagaaaaa
    13861 gtatttagta taatatcaga agcaggagat gctaaaagtg atgtaatgat gtctcttaaa
    13921 gaaataaaaa aaggtgacta caacaaagca aaacaccttt taaattcagc ttcagaaaaa
    13981 atacaaacgg catcaaaaca tcatttagaa ttactatcaa atgctatgaa tagtgaagat
    14041 agtggaactg attttttagt tgtgcattct gaagaccatt attcaaatgc attatttgct
    14101 cattctttag tatctgaact tgtagatata tttgagatga tggacccaag aattaataag
    14161 aattaaattt cttgtaaata gtgcttgaag tttggctata gtttattaaa ttagtagatt
    14221 taataaatga actccctttt actttaaagt actagtattt ataaatttat ttataaatac
    14281 agtaaatttt taaatagaaa aggagatatt attatggaaa aattttcagt agtaatagct
    14341 ggaggaggaa gtacatatac cccagaaatc atattaatgt tgctagataa cttagatagg
    14401 ttaccattaa gagcaattaa attatatgat aatgatgaag aaagacaaaa taaggtagct
    14461 aaagcttgtg aaatactaat aaaggaaaag aatcctaata tagagtattt agcaacaaca
    14521 tgccctaaag aagcttatac agatgtagat ttttgtttag ctcatataag agttggaaaa
    14581 cttgaaatga gagaattaga tgaaaaaata cctctaaaac atggggtagt tggtcaagaa
    14641 acttgtggac caggtggaat agcttatgga atgaggtcta tagaaggtgt tcttgaaaac
    14701 atagactata tggaaaagta ttctccaaat tgctggatgt taaattattc taatccagca
    14761 tcaataatag cagaagctgt tagaaggtta agacctaatt ctagggtgat aaatatttgt
    14821 gatatgccaa taggtatgga acacaatata gcaaggattg cagggcttga atctcgtaaa
    14881 catatggata taaggtactt tggattaaat cactttggtt ggtatacttc gattaaagat
    14941 aaaaaaggaa atgaactttt accaaaatta gtagagcata taaaagaata tggttttata
    15001 aatggtgaag aaggaatgaa aaatgacaag aaagatagtt ggtttgaaac taatttattt
    15061 accaaagaaa tagtaaagac agatttaacg acaataccaa gcagttactt aaaatactat
    15121 ttatttccag attatgttgt aaatcattct gatgtaaatt atactcgtgc caatgaagtt
    15181 attgatggaa gagaaaaaga agtttttggt tcatgtgcat tgatagaaaa gcaaggtcat
    15241 tctaaaggta gtgggcttaa gataggaata catgcagagt ttatagtgga tttagctaca
    15301 gctctagctt ttaatactaa agagcgtatg ttattgatag ttcaaaataa tggagctata
    15361 gaaaatatac aagatgatgc tatggttgag attccatgta tagtggggaa agatgggtat
    15421 gaaccattat caatagggga aatcccaaca ttccaaaaag gtctaataga gcaacaatta
    15481 gcagttgaaa aattagtggt tgatgcttgg attgagaagt cgtataataa gttgtggcaa
    15541 gcacttatgc tatctaagac agttccgagt gcaacagttg caaaagaatt actagatgat
    15601 ttaatagaag caaacaaaaa ttattggcca gaacttaatt aaaaataata tattttttaa
    15661 agttcctaca gtttagtaca tagcatagtt aatgtatttg taggaacttt atttatgatt
    15721 ttataagttt gtctatgaca atcttatttc ttcaagactt gtaaataatt tgttatttat
    15781 agtattaata aacttgctaa acaagtagta tccgtattta cagatgatat acaagtagca
    15841 aatatagtgt attttacagt taggatggta ggatttagtt acttgttagt tggattaaat
    15901 ttatgtacaa tagtttactt caatcactag aaatagtttg agaagttgta taataaaaaa
    15961 tttacacttt taacaggatt tatgtaggtg tttatagaaa taaataaata tgtacataat
    16021 acataattat ttttaatcct aaaatacaag aatggagaga tggctatgaa gtggagagat
    16081 tatgctgatg atgtaaattt atttgaggat tttgataaaa ctatcaagcc tctaactgac
    16141 gaacaaagaa gaaaaaatat aaacacttta attgcatatt tttcaaaaga agttccttct
    16201 aaaatataca atttatcaaa tgatgaaatt aagcctagag atatacttag aggacttttg
    16261 aatgtatatc caccaaaaga aattgctcca gagatactta atatgttaca taatttattg
    16321 ttgattgaat gtgaagaaag agagttagta gatgtaaatg atatagaaga agttgaggaa
    16381 gggattgcca tatggagagg taatataacg aatttaagag cagatgcaat agtgaatgct
    16441 gcaaataaca agttattagg gtgtttacaa ccattacatc tatgtgtaga taatgagata
    16501 cattcatgtg caggacctag acttagagaa gattgtaaca aaataataaa aaaacaagga
    16561 catttagaat atactgggga tgctaagata actagaggtt attgtttacc tgcaaaattt
    16621 gtagtacata ctgttggacc tattgtgtct ggtggtcagc caagtaaaga gcaagaaaag
    16681 caattacttc attgttataa atcatgttta aatacaataa aagaaattga tgaaataaaa
    16741 aatattgttt tttgtggaat ttctacaggt gtatttggtt atccaaaaaa agaggcagct
    16801 aatcttgctg taagtagggt tagattatgg ctaaaagaaa accctgaaaa aaatttaaaa
    16861 gttgtattta atgtttttac tgaagaggaa gaagagaaat atagaagaat atttaaataa
    16921 tattatataa caaatcctaa aaatacttat tatataatcc tataatacaa attcattgta
    16981 taagataata atttgcaagt agtaaaaatt aataaaatat aatttgtatt tttaataaat
    17041 aa
//
LOCUS       DAMKOJ010000072        16921 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000072 DAMKOJ010000000
VERSION     DAMKOJ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16921
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.078"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            285..743
                     /locus_tag="PC592_002737"
     CDS             285..743
                     /locus_tag="PC592_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4056687.1"
                     /translation="MEFINFVSDKVIELKMDCKTKENFFKEIHNKVFDLGFVKEEFGE
                     KILERENVFPTGLNLGDYGVAIPHTDAEYIKEQFIAVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            796..1071
                     /locus_tag="PC592_002738"
     CDS             796..1071
                     /locus_tag="PC592_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4056688.1"
                     /translation="MKKILVACGAGIATSTVVCDKVEKLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1130..2404
                     /locus_tag="PC592_002739"
     CDS             1130..2404
                     /locus_tag="PC592_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF4056689.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKLVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLLLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2535..3587
                     /locus_tag="PC592_002740"
     CDS             2535..3587
                     /locus_tag="PC592_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF4056690.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYANIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDVNPVEK
                     IKELTDGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3587..4618
                     /locus_tag="PC592_002741"
     CDS             3587..4618
                     /locus_tag="PC592_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDF4056691.1"
                     /translation="MKAVVKTKPGYDNVEVLDVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCQTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4709..5521
                     /locus_tag="PC592_002742"
     CDS             4709..5521
                     /locus_tag="PC592_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF4056692.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVMVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5524..6444
                     /locus_tag="PC592_002743"
     CDS             5524..6444
                     /locus_tag="PC592_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF4056693.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGVNVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6619..7065
                     /gene="rpiB"
                     /locus_tag="PC592_002744"
     CDS             6619..7065
                     /gene="rpiB"
                     /locus_tag="PC592_002744"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF4056694.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEIEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7095..7760
                     /locus_tag="PC592_002745"
     CDS             7095..7760
                     /locus_tag="PC592_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF4056695.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVRADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYIGLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIKELKE
                     SIK"
     gene            7870..9372
                     /locus_tag="PC592_002746"
     CDS             7870..9372
                     /locus_tag="PC592_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDF4056696.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVRKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSAVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGSIMITASHLPYYYNGLKFFTESGGLEKADIKEMLDIADKNDSVDYEKANKKGKV
                     ISKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRYKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAREEKEVRIGINKEDFRPYAEDILKDLDSHVRSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLRGL"
     gene            complement(9684..11276)
                     /locus_tag="PC592_002747"
     CDS             complement(9684..11276)
                     /locus_tag="PC592_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4056697.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLISILFEAVYDLNNNFFYN
                     INYYYKEFTIPYFYFFGTPLHLSKVELEFVCIGVILSSFLLIVLCFILYKKNKQTKVK
                     FLENVISLFSKVKIELTLILILILLILRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLSVYNRKTINKKLAIVFLISIVMQAIIQNMVLIFF
                     MYIYYAEAIAIVILFTLVNTVFHLYIYNFLSAKFNYINNISKNVKNIENGDLKYKLEV
                     IGNDEISDLSKSINNITDGLENAVDSSIKNERMKTELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDKETVNDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSNLDFIIETPEHAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELVERFRRGDVSRKTDGSGLGLSIAQNIIELEN
                     ADMEIIIDADLFKVMLTFRRVN"
     gene            complement(11245..11961)
                     /locus_tag="PC592_002748"
     CDS             complement(11245..11961)
                     /locus_tag="PC592_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056698.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLKPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKVIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSREIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(12504..13304)
                     /locus_tag="PC592_002749"
     CDS             complement(12504..13304)
                     /locus_tag="PC592_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF4056699.1"
                     /translation="MTFKNKKFTISKYRILSIILALCLILTAFSSYMNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTDIQK
                     SEYRNREFLASLNSLGVRRENIILLPETNTNGNTDFNYMEKIAINFEENFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEDREGIGYKSDHKSFDKLLRNKDVPAILHTPNL"
     gene            complement(13616..14347)
                     /locus_tag="PC592_002750"
     CDS             complement(13616..14347)
                     /locus_tag="PC592_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056700.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIIGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLYDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEICAKNFPKFIKREFDNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTVSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(14334..15029)
                     /locus_tag="PC592_002751"
     CDS             complement(14334..15029)
                     /locus_tag="PC592_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4056701.1"
                     /translation="MLKIRNLSLDLPNFKLQENSLNINNHEYFVLLGSSGSGKTLFLE
                     TLAGRYPSAKGSVSFKKNLISSLPPENRNIGFVYQNFELFPNMNVEDNISFPLKLRKI
                     PIDEQILKVNHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKHKGESFFYEYI"
     gene            complement(15031..15822)
                     /locus_tag="PC592_002752"
     CDS             complement(15031..15822)
                     /locus_tag="PC592_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056702.1"
                     /translation="MKNKFFTILLTGFFAVVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKILKLDFVFTKQGIILAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFKFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(15832..16644)
                     /gene="modA"
                     /locus_tag="PC592_002753"
     CDS             complement(15832..16644)
                     /gene="modA"
                     /locus_tag="PC592_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4056703.1"
                     /translation="MFKKFSVLILSMIISLSITACNSKENKANNESNAKVTTANDSKE
                     KETLFVYSGAGLKKPMDEIAQKFEKENNIKIEYSYAGSAQLIAQIETSHKGDAFIVGS
                     EPIYSKAFEKKLVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNRDGVKLIFGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIASDEAKQIFKKYGFEPVK"
BASE COUNT         6473 a         2076 c         2678 g         5694 t
ORIGIN      
        1 taaaaaacca tttataaaaa acaaaaaaat catttctcta acaaaaaaaa ccacaaaaaa
       61 tataaaaaag tatggctagt taagtgatta acaagtaaaa attaaaataa aaatcaaaaa
      121 aaatttatca atgaaagtca gctaaaatcc tagaagagag cattatttta aggaaaacat
      181 tttcttttgt ttgacaaaaa aagccacttt ttggcacaca acatgcttta tataaagtca
      241 agaaaaacta aggtacaaga caaaggcaat taggaggtgt aaatatggag tttataaatt
      301 ttgtaagtga taaagttata gaacttaaaa tggattgtaa aacgaaagaa aatttcttta
      361 aagaaataca taataaagtt tttgatttag gctttgtaaa agaagaattt ggagaaaaaa
      421 tattagaaag agaaaatgta tttccaacag gattaaattt aggtgattat ggagtagcca
      481 taccacatac agatgcagaa tatattaaag agcaatttat agcagtctgt acttttaatg
      541 aaccagtagt atttagttct atggaagacc aagatgaaaa agtacctgta aatttggctt
      601 tcgtattagg acttaatcaa ccacacagtc aattatctgt attaacagaa ttaatgggaa
      661 ttatgcaaaa taaagagtta gttgataagt tgatgagttc tactgataaa gaagaagttt
      721 taaagacact aaagtcttta taaaaataaa aaagtactaa aaataaaaaa taaaaattat
      781 taggaggaaa taaaaatgaa aaaaatatta gtagcatgtg gagcaggaat agcaacatca
      841 acagtagttt gtgacaaggt agagaaatta gttaaggaaa ataatataca agcagaagtt
      901 atacaatgca aaatagctga atgtgcaaca aagcaagaag gagcagattt aatagtatca
      961 acaactatat taccaacaac ttataatata ccagcaataa aagcaacagc atatataact
     1021 ggagtaaata cagcagcatt agataaaaaa atattagatg ctttaaaata atcctatcat
     1081 agatacattg aaataatatt ttataaaaca gaaaaaggag gatttataaa tggataaatt
     1141 attagcagta gtacaataca ttttaaatat gggaccgaca gtaatactac caataacaat
     1201 tgtagtacta ggaatgatat ttagaattaa gtttacaaaa gctttaaagt caggtcttac
     1261 aatcggtata ggatttgtgg gtataaactt agttgtaaac ctattaacat caacattagg
     1321 gccagcggct caaggaatgg ttgaaagatt cggacttaat ttaacagtaa tcgatgttgg
     1381 ttggccaaca acagcatcag caacatgggc ttcaccagtt gcaccaatat taataccagt
     1441 ttgtttatta gtaaacttac tattattata cttcaataaa acaaagatat taaacgttga
     1501 tatatggaat tattggcact ttatagtagc aggtgcggtt ggatatatag taacaggaag
     1561 ctatgtttgg gctatattct gtgcaatatt aatggaatta ttagtactat ttattgcaga
     1621 aaagacagca aaaaatgttc aggagtttta tgatttagaa ggtatagcat taccaactgg
     1681 ttcaacagct tcatttgctc cacttggata tttagtaggt aaacttgttg aaaaaatacc
     1741 aggaataaat aaaatacaag cagacccaga ctctatacaa aaaagatttg gtatatttgg
     1801 agaaccaatg atgatgggga ttatactagg tataatactt ggagcacttg ctggatatga
     1861 tgtagcagga atatttaatg taggtatatc aatgggtgca gtaatgttac ttatgcctag
     1921 aatggttaga atattaatgg aaggtttaat tccaatttca gaatcaataa gagatttctt
     1981 acaagcaaaa tatggagaca gagaacttta tataggacta gatgcagcag tagcaactgg
     2041 acatccagca gttatatcaa cagctcttat actagttcct ataactttac ttttagcagt
     2101 tatactacca ggaaacaaag tcttaccatt tggagactta gcaacaatac cattttatat
     2161 ggcatttata gtgtgtttta gaaaaggtaa tatagttcaa tcagttataa caggaacaat
     2221 agtaatagct atatcacttt atatggctac aaactttgca gatgttcata cacaattatt
     2281 acaacaagca aatatgatgc cagaaggaac aacaatggtt acaagtatag atacaggtgg
     2341 aaacttgcta aaatggggaa tattgaaatt atctcaatta gtttcttcat ttggaatatt
     2401 ctaatatgta gttaatatag attactcttt tttagtaaag tatgcgaaaa tttaatattt
     2461 agcaactact aaaaaagagt aatatttttt ataaattttt aaagaataca aaatacaaga
     2521 ggaggagatt tatcatgaaa gcagcagtat tacatggcac aaatgatatg agatttgaag
     2581 atatagaaat aaaaccatgt gaaagtgatg aagtaaaaat aaaagttatg gcagcaggaa
     2641 tatgtgggtc agatcctcca agagtattaa aacattggaa atatccagtt ccagctatac
     2701 caggacatga gttttctgga gtaattgctg aagttggtaa ggatgtaaaa aatgtaaagg
     2761 ttggagatag agtagttgca attcctttta taccttgcaa tgaatgtgaa tattgtaaaa
     2821 gaggattatt ttcattatgt gatgaccatg gaatgttagg agctaaaagt tttggagctt
     2881 ttgcagagta tgcaaatata aaggctacaa atgtacttcc aataggagac atggactttg
     2941 aagatgctgc catgatagag ccactagcag ttgctatgca tggagtactt aatataggtg
     3001 ttcaagttgg agacactgta gcagtaatgg gtagtggaac aatgggacag ttagtaatac
     3061 aaggacttaa aatagcagga gcaggaacaa ttatagcagt ggatatatct gataataaat
     3121 taagagaatc aaaggaatta ggtgctgata taataattaa tgctaaagat gttaacccag
     3181 tagaaaaaat aaaagaactt actgatggaa aaggtgttga tatagctctt gaatgtgcag
     3241 gttcaaaaat aactcaagaa caatgtttac ttataactaa aaagaaaagt aagataggat
     3301 ttttaggaat agcatattca gatataactt tatcagaaga agcatttgaa aatatattta
     3361 gaaaagaact agagttaaaa ggtttttgga actcttattc tgcaccattc ccaggacaag
     3421 aatggactaa gggaatcaat ctagttaatg aaggaaagat aaaattaaaa gaaatggtat
     3481 ctcatagatt ctcacttgaa gatacttaca aagcatttga aatgataaga gatagaaaag
     3541 aagaatttaa taaaatatta attttaccac aaggggttga aaaataatga aggcagtagt
     3601 taaaactaaa ccaggttatg ataatgtaga agttttagac gtagaagaac caaaagctac
     3661 aggagacaag gttaaaataa aagtagaata tagtggtata tgtggttcag atatacattc
     3721 atttaaaggt gaatatgcaa atataaaagc cccagtaaca ttaggccatg aattttctgg
     3781 aattgttgta gaagtaggag aagatgttaa aaatataaaa gtaggagata gagttacatc
     3841 agaaactact tttgcgactt gtgaaaaatg tatatactgt gaaactaaag attataactt
     3901 atgccaaact agaaaaggta ttggtactca agtaaatgga agttttgctg agtatgtact
     3961 atcaagagaa gaaagtatac atgtacttcc tgaaaatgta tctttattat cagcagccct
     4021 tacagagcca ctagcttgtt gtgttcatgc agctcttgaa aagactacta tagaaagctc
     4081 tgatacagtt ttaataatag gaccaggacc aattggttta ttattagctc aagttgttaa
     4141 atctcaagga gctacagtta taatgtctgg tgttacaaaa gacaaggaaa gattagaaat
     4201 agctaaaaat cttggagtag atagaactgt aaatgtaatg gaagaaagtt tggcagatgt
     4261 agtgaatgaa atgactgatg gaaatggagt aaacaaagga tttgattgtt ctggatttat
     4321 gccagcagtt aacgaagctt taagattgct tagaaaaaaa ggtactttcg tacaagttgg
     4381 aatctttgct aaaaaattaa atgaaatgga ccaagaagca ataatccaaa gagagttaca
     4441 atatatagga agtagatctc aaaagccaag ttcttggatt acagcattag atttaatggc
     4501 aagtggaaaa gtaaatacag aagctttagt tactagaact gttggtttag acgaatttaa
     4561 agaaggtatt acagctttaa tgaacgggga agaaataaag gtagcagtaa aatcttaaaa
     4621 aaacatttgt attattttaa aaaaaattgt aaaatctact gtaggataaa aaatgtaaga
     4681 tcttaaaaaa taacaggagg aagaaagtat gagcactctt agagatcatt ctaataatat
     4741 tagaaaaaac ataataaaaa tggttgcaga agctaaaagc ggacatccag gtggttcatt
     4801 atcaatagct gatatgttga cagtattata ttttgataag atgaacgtat gtgcagaaaa
     4861 tccaaaaatg gctgatagag atagatttgt tctatcaaaa ggtcatgcag caccagcact
     4921 atatgctaca ctagcagaaa aaggattttt cccagaagaa gaattaataa cactaagaaa
     4981 atttggttct aagttacaag gtcacccaga catgaaaaaa gtagcaggaa tcgatatgtc
     5041 tactggttct cttggacaag ggctatctgc agcaaatggt atggcacttg caggaaaatt
     5101 agacaacaaa gactatacag tatatactat attaggtgat ggagaaatcc aagaaggtca
     5161 aatatgggaa gctgcaatga cagcatcaca ttacaaatta gataatttaa ttgcatttgt
     5221 tgacttaaat ggattacaaa tagatggttc taatgaagaa gtaatgaatg taaatccagt
     5281 agatgacaaa ttcaaatctt ttggatggaa tgtaatggta ataaatggac attcttttga
     5341 agaaatagga aatgcagttg atgaagctaa aaaagttaca ggaaaaccaa ctgtaataat
     5401 agctaaaaca gtaaaaggta aaggtgtttc atttatggaa aataatgctg catggcatgg
     5461 aacagctcca aatgcagaac aagcagagca agcattgaaa gatttagaag gaggtctata
     5521 ggaatgggaa tagcaactag agaagcttac ggacaagtgt taaaagaact tgcagaaaat
     5581 aaagatatag tagtattaga tgcagattta ggaaaagcca caaaaagtat atcatttaaa
     5641 gaagttgccc cagatagatt ttttgatatg gggatagcag aaggtgatat gattggtaca
     5701 gcagcaggtc ttgctacttg tggaaaaata ccttttgcaa gtacgtttgc aatatttgca
     5761 gcaggaagag gctatgagca aataagaaac tctgtagcat atccaaattt aaatgttaaa
     5821 atagcagcta ctcatgcagg tgtaacagta ggtgaagatg gtggtagcca tcaagctata
     5881 gaagatatat ctctaatgag aggtatacca aatatggttg tattaaatcc agcagatgct
     5941 ttagaagcaa gacaagctat tcttgcatct attgattata atggacctgt ttatataaga
     6001 ttaggtagag ctgcaactcc tgatgtaaac agtgaaaatt ataaatttga aataggaaaa
     6061 ggaactgttt taagagaagg ttctgacata acagtgatag ctacaggaat aatggtagca
     6121 aaagctttag aagcagcaga agaacttgct aaggaaggtg taaatgtaga agttgttaat
     6181 atatctacaa taaaaccatt agatgaagca ttaataaaag aaactgctaa gaaaactgga
     6241 aaagtagtta cagcagaaga acacagtata ataggtggtt taggttcagc tgtatgtgaa
     6301 gctttagcag aaactaaaga tgtagtagtt agaagaattg gtgttaaaga tgtatttggt
     6361 caatcaggta caccagctga tttattaaaa cactatggct taactacaga agatatagta
     6421 aaaaatataa aagaattgtt atagatataa atatatctaa ataacaaatt gatttgacat
     6481 aaatcaatta aagctgtctt aaaaatagaa agaaatttct acaatgggac agctttattt
     6541 ttacaatact ttatttttat gataattgta aaatagtata aaaataatca aaaaaattat
     6601 agaaagaggt gctatttaat gaaaatatct attggatgtg accatggtgg ttatgaatta
     6661 aaggaatata taaaggaaaa cttaataaat aaaggtatag aaattgaaga tgtgggtaca
     6721 aattcaaaag aaagcgtaga tttcccaata tatgcaaaaa aggtaagtca aaatgttcaa
     6781 agtaaaaaat ctgatttagg tatactttgt tgtggaacag gaataggtat gtctattgca
     6841 gcaaataagt ttaaaggaat cagagcagct gttgtttctg actgtttttc agctaaggcc
     6901 actagagaac acaataatac aaatgtactt tgtttagggg aaagagttat tggaaaagga
     6961 ttagcaatga gaattgttga agaatggtta aattcaagtt ataatggaga aagacatgca
     7021 agaagattac aaatgattga tgatatagaa aaagaaaatt tataaatata taatttataa
     7081 taagggggaa cgttatgtct attatttgtg cttcaataat gtgtgcagac caaatgaagt
     7141 taaaagagga attagaagct cttgaagaag caggagtaaa attacttcat tgtgatgtta
     7201 tggatggaat atttgttaaa aacttggcta tggggccaga gttattaaaa tcaataagtg
     7261 aaaatacaac aataccttta gacatacact tagccacaga aactccagat aagtatattg
     7321 atatgatgtc ttatataaag ccaaaatata tttcttttca tgtagaatca agcacaaatg
     7381 taagagctga tatacaaaaa ttaagaaatt atggtatagg gccagtatta gcaataagcc
     7441 ctcaaacaag tgtggataaa atagaagaat atataggttt agttgagggt atcttagtaa
     7501 tgacagtaaa tccaggattt gcaggtcaaa agtttaatct ttctgtattg gataagttgg
     7561 ataaacttac agagatacta aaagattatg ataatcctcc atttatagag gttgatggaa
     7621 atataaataa ggatactatt aaacttatga atggtaaaaa agtagatata tatgttgttg
     7681 gtacttcagc tttatttaat gacaagcctc caatttcata taaagataaa ataaaagaac
     7741 taaaagaaag tataaagtaa ctatgtaata aaattataat atgtttctat ttaatggtaa
     7801 aattttaggt agaaacaaga aattttgtaa tatttaataa aaattttggt tggataagga
     7861 gagtttttta tgggagacct atataaactg caaaatggta ctgatattag aggaatagca
     7921 tatgaaaatg attctaaaga agttaaccta actgtagaag aagtaagaaa aatagctaaa
     7981 gcgtttcata tttggctgaa agaaaagact aagaaagata aagtaactgt tgctatagga
     8041 actgattcta ggataacagg aagccaattt agaagtgctg tcattgaaac tttaactaat
     8101 gatgattgta atgtaattga ttgtgagatt gcaacaactc cagctatgtt tatgacaact
     8161 attatggatg gatataattc tgatgggtcg attatgatta cagcaagcca cttaccttat
     8221 tactataatg gtttaaagtt ttttacagaa agtggaggct tagaaaaagc tgatataaaa
     8281 gaaatgttgg atatagctga taaaaatgat agtgtagact atgagaaagc aaataaaaaa
     8341 ggtaaagtta tatcaaaaaa cttaatagaa gattattcta atttattaat agataaaatt
     8401 agaaaaggtg taaattcaag taaaaattat gaaaagcctt tttctggact taagatattg
     8461 gttgatgcag gaaatggagc tggtggattc tttgctgaaa aagttttaca catactggga
     8521 gcagatacaa caggtagtca gtttttgaac ccagatggta tgtttccaaa tcatatacct
     8581 aatcctgaaa ataaagaagc aatggaaagc atatgtaaag ctgtgttgga caataagagc
     8641 gatttaggaa taatatttga tacagacgta gacagagctg ctattgtagg taaaaatgga
     8701 aaaccaataa ataaaaatgc tcttatagct gttatatcat caatagtatt agaagaacat
     8761 ccaaaaacag ctatagtaac agattcgatt acttctgagg gacttgctaa gtttataaat
     8821 gaattacaag gaagacatca tagatataaa agaggatata aaaatgtaat aaatgaagct
     8881 ataagattaa atagtgaagg tgaagagtgc catttagcta tagaaacatc tggacatgct
     8941 gctttaaaag aaaattattt cttagatgat ggggcatatt taatagctaa aattttaata
     9001 aaagtagcaa aactatcctt agaaggaaag actatagaag aattaataga aaaccttgaa
     9061 gaagctcgag aagaaaaaga agttagaata ggcattaata aagaagattt tagaccatat
     9121 gcagaagata tattaaaaga tttagattct catgttagga gtattgatgg atggtctgta
     9181 gcaccaaata attttgaagg tataagagtt aattgtgatg aatcaaatgg agatggatgg
     9241 tttttactta gaatatcact acatgaacca ttattagctt taaatattga atcaaataaa
     9301 attggtggag cagaacaaat ttattctaag ttaaaacttt tcttagaaaa atatgattta
     9361 agaggtcttt agggtaaata gaaagaatat atttatatcg aagaatatat gtaaatttgt
     9421 acctaagatt acaaatatta caaaattgta atcttaggta acagagatgt aactgattat
     9481 ggaaacacta tgtgatatta taaatacaga gagatgaaat acatgctgaa ttatagagaa
     9541 atataattta aaatgtatta atatcacacc aaaaaggtat aatcaaaaaa tatgtaaata
     9601 taaaccccaa catttagaaa aagacctcga aggaggtttt tttcttgttt aaataactta
     9661 aaatatattt ttatattaat gtatcaatta actcttctaa aagtaagcat taccttaaat
     9721 aaatcagcat ctataattat ttccatgtct gcattttcta attcaattat attttgagca
     9781 atggataaac caagaccaga gccatctgtt tttctagata catcacccct tctaaatctt
     9841 tctactaact cttctggctt taggtttagt ttatcatttg aaatattttt aaatgttaat
     9901 attatatttt cttcctttat aaacatatct atatagactc tagtattagg catagagtat
     9961 tttagtatat tgcaaattag attttcaaaa actctccaag ttttttttcc atctatcatg
    10021 gtaaaaacag catgctcagg tgtttctatt ataaaatcta aattgctatt ttgaattttg
    10081 tcttcaaact ctacaatact ttgaattaaa agttctctta tatctgtttt tgttatatta
    10141 aattctacat ctccactact tagcttagat gcttcaaata tgtcatctat taataatttt
    10201 aatctttgtg attttttatc taaaatattt atatagtcat ttacagtctc tttatcaaag
    10261 tcattatttt ttaacatatc aacatagctt aatatagatg taagtggagt ttttaagtca
    10321 tgagatacgt ttgtgataag ttctgtcttc atcctttcat tttttatact agaatctaca
    10381 gcattttcaa gaccatctgt tatattattt atacttttag ataagtcaga tatttcatca
    10441 tttcctatta cttctagctt atactttaaa tctccattct caatattttt tacattcttt
    10501 gatatattat ttatgtaatt aaacttagca gataaaaagt tgtatatata taaatgaaaa
    10561 actgtgttta caagtgtaaa taaaattact atagctattg cctcagcgta atatatatac
    10621 ataaagaata tcaaaaccat attttggata atagcttgca taactataga tattaaaaat
    10681 actatagcta attttttatt tatagttttt ctattataca cactaagtaa gtttgaaaag
    10741 aatacatatg ttatagacat atcttttaga ttatagttat tatatttaat attttcatat
    10801 attatgtaga ctatagatat aattataaaa ttgtagatta ttagattagt gttgtaaaac
    10861 attttattac ttgtaaaggc atgaaacctt aaaattaata gtatcaaaat taatataagt
    10921 gtaagttcta tttttacctt agaaaaaagg cttatgacat tctctaagaa tttgacttta
    10981 gtctgtttat tttttttata caatataaaa catagtacaa tcaataaaaa acttgataat
    11041 ataacaccta tacagacaaa ctctaattct acttttgaca aatgtaaagg agtgccaaaa
    11101 aaataaaaat aaggtatagt aaactcttta taataataat taatattata aaaaaagtta
    11161 ttattcaaat cataaactgc ttcaaataat atagaaatta atagaaacag tagtaataat
    11221 aaaataaatt ttgctttaga atcattaata attaagtttt tcaattttgt aaccaatgcc
    11281 ccacaccacc tttaaatatt ttggttcttt tggattaatt tcaatttttt ctctaattct
    11341 tctaatatga acagcaatag ttctctcaca actataagca tcctcattcc agacattttc
    11401 ataaatctca cgagaagaga aaattttacc ttttcgtgac ataagaagag taagtatttt
    11461 atattcaagt ggtgtcattt taatttcttc cccatctaaa gaaactattt ttgtatctgt
    11521 atttagctct agtccaccac tttttagaat ataattagta tcatttgagt tatttgtatt
    11581 actaaaatca cctaaattta tgtatcttct aagttgagat tttactctag cagtaagttc
    11641 taatggatta aatggtttag ttatatagtc atcagcaccc atattaagtc ctataacttt
    11701 gtccatatct tctgattttg cagataagag aatgattggt atatttcttt tttctcttat
    11761 tttaagtgta gttttaagcc catctaaatt gggcatcatt acatccatta ttattaattt
    11821 aatatcattt tcgattagta tatccaatgc ttcaagtcca tcatatgcct ttaaaacatt
    11881 aaagttatca ggttttaaat agaattctat agcatcaact atctctctat catcatctac
    11941 aaccaatata ttttgattca atttattaac ctccttgaaa ttttattttt aaccaatctt
    12001 tattttatac caaaaagaag tattagaaaa cagtaagcat atttgttatg aaataaaaac
    12061 taatactttt aatatattgt caatgcatat agtaattttt aaagcataga tgtatatatt
    12121 aatatgaagt taaaagttta tgaaaatatc taggataatt tatcacactc cttatgtcat
    12181 tttatgttta ttaatttttt aggtctaaac atatactaac aaatataaat aacaaatgag
    12241 tttcataatt attaagaatt tataacaaat atttattttg atgtatttta atataaatag
    12301 gtagtttaat gtagatatgc ataaaacctt taagaagaaa acttataggt ttcaataata
    12361 atatttttat atattttaag acatgatgaa tctagatatg gggaatagtt ggatgagaaa
    12421 aagtagtata gcacaaaaaa gtgctatatc acaatctcaa ataatttact ttttataatt
    12481 taagctaaaa gaataaatat ttcttataaa ttaggtgtat gaagtatggc aggaacatct
    12541 ttattcctta ataatttatc aaaagattta tgatcagatt tataaccaat accttctcta
    12601 tcttctaact catcaacaat tttgtattgt tgacaggcat tttttacctt ttcatagtct
    12661 tcagtagaat gagctttata aactatttta ttattaaaag ttattttatc agcaaatttt
    12721 ggttttacaa aatatttggc atcttttatt ttaccagcat tatataaatt ttgtataaca
    12781 gaaccatttt ttaaatgttg caaatggtcg tctaacttat aagtatgtgc tatatgagtt
    12841 acatttttaa aattttcttc aaagttaatg gcaatttttt ccatgtaatt gaagtcagta
    12901 ttaccatttg tatttgtttc tggtaataat attatattct ccctccttac accaaggcta
    12961 ttaagagaag ctaaaaattc tctgtttcta tattctgatt tttgtatatc tgttagattt
    13021 tcatactttt tatatttatc aaatacagat atgccacatc cagtagatac caaaaccaca
    13081 aatacatgat tttttcctct ttcttttata gcattaacaa tagcactccc agcccacaac
    13141 acttcatcat cttgatgttg aacatagaag acaacataat ctttaaattt tttatgacta
    13201 taattcatat agctgctaaa agcagttaaa atcaagcata aagctagaat gatagataaa
    13261 attctatatt tacttatagt aaatttttta ttcttaaatg tcatttaatc atctcctgaa
    13321 aagttgtctt agttatatta tcaaacaaag tgctaaaaat tatttcttaa atactgaaaa
    13381 atatagagta gattaatgga ataaaatttt tttattaatt taaaattaag aaaatattta
    13441 tgtataaaac caatcaaaat attaattagt gataggaatt gagatttaaa gggattgtac
    13501 atttatttga gattcattta tatagcatta ctttagtatt gagaataaaa gtaataacta
    13561 tttaaattta aagagtacac attgatattt gtgtactctt taatgatgtg attgcttatt
    13621 tactacaaaa acatagtctt tttaaaccta aaatatttga tgcaccagct atcgtagtgc
    13681 cataatagta aactggttta ttaagtgata gaaaatttat aattgagtta ttacataatg
    13741 tacttactgt gcaaatcact aaatcagccc aagatattac atcttcataa tctcgtatac
    13801 catcttcaat cttaacatta tactgaatag tatctacaaa ttcaggattt aaatctaata
    13861 ctcttgtttc gaaaaagtcc ttaatattat caattatggc tggttgatat cctataattg
    13921 ctacttttgg gttatcaaat tcccttttta taaacttagg gaagtttttt gcacatatct
    13981 ctggttcatt atttttacaa tgaatcgttc tatccgtctt acctaagtat ttcataacag
    14041 catttaatga tgctataaaa agacttctgt catgaggatt atcatataaa tctaatgata
    14101 atatatcttt taaagaacct tcaaacgtag atggagtaga agtaaatgct tgtcctttag
    14161 ctcctttaaa gtcagcttca agcattattt ctttaccaat tataattgga aaatctttac
    14221 gcttagtatt tccaattgct tcttttgaag atagcgattt ggatacaata cttatcatat
    14281 ccatatttaa attatattta tctacttgta ctaatagata atctctcaaa atatcaaata
    14341 tattcataga aaaaagattc tcctttatgt tttatttctt catttaaatc aaaaatatga
    14401 tttatttttc cattgttcat tattcctatc ttatgagcaa aaaacattgc ttcagaaata
    14461 tcatgagtaa catgaatcac cgttggtttg tattttatgt agacatcctt caaaattttg
    14521 cttatatgtt tttttgtaat ataatctaat gaactcatag gttcatctaa aagtaatata
    14581 tcaggttcag ctattaaagc acgtgcaaaa gcaactcgtt gcttttcccc tccacttaaa
    14641 tttttaggat atctattttt tatatcctct atctgcatta atttagacaa gtggttaact
    14701 ttaagaatct gttcatctat aggtattttt cttaatttaa gtggaaagct tatattatct
    14761 tcaacattca tatttggaaa taattcaaaa ttttgataca caaatcctat atttctattt
    14821 tctggaggta agcttgatat taaatttttt ttaaatgata cacttccttt agcagatgga
    14881 tatcttcctg ctaatgtttc tagaaataga gttttacctg agccactaga tcccaataaa
    14941 acaaagtatt catggttatt aatatttaaa ctattttctt gtaatttaaa attaggtaaa
    15001 tcaagagata aatttcttat ttttaacata ttaattttta tcaacctctc tattaaaaaa
    15061 tatctcaaaa agcatcaagc atgtaagtga gataaatatc aaaattacag ctattccaat
    15121 tgcaatatct atatcaccag tagacatatt taaatatata gatgtaggaa taatttcagt
    15181 tttcatacgt gtagaacctg ctatcatagc tactgcacca aattcaccaa gtgctcttga
    15241 ccaagtcatt acagttgcag atatgattcc agtttttaga tttggaagaa ttataaattt
    15301 aaatgcttcc caactattac atccaagagt acgtgcaaca aatatcatct tttcgttact
    15361 ttcatttagt gaagtgtgaa gtattttaat agtaagtgga agatttacaa atacttgtgc
    15421 caaaattata ccttgctttg taaatacaaa atcaagctta agaatcttgt aaatggaatc
    15481 tccaatcccc attcttccaa acaaaagcaa gagagcaatt cctgatacta ggtggggaag
    15541 agacataggg agatttatta tctgtataat cagtttttta aatggtaatt tagtaatatg
    15601 taaaaagtat gctactggaa tagctaacaa aaggcatact atagtagata ttaaagatgt
    15661 tttaatacta agtgttattg catactgtac ctccactgat tttaagcata taggaacata
    15721 acttatccct ttaatgatta acataagaag tggtgataca ataaataaaa agactacagc
    15781 aaaaaatcca gtaagtagta tagtaaaaaa tttatttttc aagtttaatc actacttaac
    15841 aggttcaaaa ccatattttt taaatatctg tttagcttca tctgatgcta tgtagtttat
    15901 aaatttatta gctaaatctt ttttatcact atagtttacg attcctgctg atatgagttg
    15961 gtctatgttt ttatcttgag caatttctat aacttctaca tcctcattgc caaagactga
    16021 atcttttgtg gctattgtag catctgcttt acttgatgtt aactgtacaa tcatttcatt
    16081 tacagttgca gctgtagaga caacattatc atttatagat tttaaattat ttttttcaag
    16141 tattttttgc gtagtcttac ctatggcatt agactctttg tctccaaaaa taagtttaac
    16201 tccatctcta tttaagtctt ccagtttttg aatattagct ggattccctt taggtacaac
    16261 tattgcagga gtatgatgtg caactgtttt atgttcacct acaagttttt tttcaaaggc
    16321 ctttgagtaa attggttcag aaccaacaat aaatgcatct cccttgtgac ttgtttcaat
    16381 ttgagctatt agctgtgcag agcctgcata gctatattca attttgatat tattttcttt
    16441 ctcaaatttt tgagctattt catccattgg tttctttaaa cctgcacctg aatatacaaa
    16501 aagagtttct ttttcttttg agtcattagc tgttgtcact ttagcattag attcattatt
    16561 cgctttgttt tctttagaat tacatgcagt aatacttaat gaaataatca tagataaaat
    16621 tagtactgaa aattttttaa acataatata ttcccccttg gtaaattagt gtaaattctt
    16681 tttttagtat atcatactaa gaaaacgatg tctaagcttt tgttatgttt tataatgttt
    16741 tgttatgttt tgtcatgtgt ggttaagaga aaatctatct ataatgtcat tttcatagag
    16801 agttatttca tttttaactt ttattaatac tttaaagtat tttaaattta aaaactattt
    16861 ttaaattaat cgattgtagt ctttttattt tttaaatgaa tttattttat atttatacat
    16921 a
//
LOCUS       DAMKOJ010000073        16845 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000073 DAMKOJ010000000
VERSION     DAMKOJ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16845
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.079"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            50..355
                     /locus_tag="PC592_002754"
     CDS             50..355
                     /locus_tag="PC592_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056704.1"
                     /translation="MPSMIMEIVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     IGIIAAGIALIFFRNGIDSIGSIATYGIFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            1051..1644
                     /locus_tag="PC592_002755"
     CDS             1051..1644
                     /locus_tag="PC592_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4056705.1"
                     /translation="MNYTIEPTQLNKMYKDKAVINNINIHVRKEVIYGFVVQNRAGKS
                     TVMKMLLNLTKSNSGEIIIFGKKLEETDFEMLKKISTIIENTYFYENLTDKQNLDLHC
                     EYMGYYNKEHISEILKCVGLSKQSSKKVSKYFLGIKQCLLIARAILTKPELLILDESI
                     NALDPEGIREMRELFNKLNTDYITTIFTSSHILSEVE"
     gene            2772..3422
                     /locus_tag="PC592_002756"
     CDS             2772..3422
                     /locus_tag="PC592_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4056706.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEKEDV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            3713..5779
                     /locus_tag="PC592_002757"
     CDS             3713..5779
                     /locus_tag="PC592_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF4056707.1"
                     /translation="MKEVVRSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENAYTSQVYILNNKSGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKDGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLSEEEQQKKINAYNNRHYEHFKEIPYAVNGEGYVSRKRKRLYLYDSNINELKAI
                     TAPMFNVVGMKISDGKILYVGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIVKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSEHQHHCIGNTVTSDVKMGV
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVAFL
                     GDRLPEVYTVENGTLCKKTHLNDHILEEYKISEPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLVIHGGPRLTYGPYFMHEMQVFASAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            5798..7753
                     /locus_tag="PC592_002758"
     CDS             5798..7753
                     /locus_tag="PC592_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF4056708.1"
                     /translation="MEKIKIENSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGIDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENTTKAITPKFCEVAGIDVSSDKKRILYVGQIYEDCATPFS
                     GLWEYHIESGETKELVPQGKYQISLAKYIGENKVMLQASTLDRSITQNHDIFILDLST
                     SEISMIASLDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFDEFDTNTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFIAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDICIEKYPGIDAERLGVA
                     GGSYGGYMTNWIIGHTDRFKAAASQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIVRVNAIVDWFERYL"
     gene            7769..8959
                     /locus_tag="PC592_002759"
     CDS             7769..8959
                     /locus_tag="PC592_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF4056709.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTSAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAESTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVLVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            9410..9784
                     /locus_tag="PC592_002760"
     CDS             9410..9784
                     /locus_tag="PC592_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4056710.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAS
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            9786..10643
                     /locus_tag="PC592_002761"
     CDS             9786..10643
                     /locus_tag="PC592_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056711.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVIKRDSGKIKIFGKDFNGNEKELKNRIGVVFDDSYFYDELSMAEMKSIIAP
                     SYDNWCEEDYQKNMKHFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     EEHRKVKGDIKFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            10646..11284
                     /locus_tag="PC592_002762"
     CDS             10646..11284
                     /locus_tag="PC592_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF4056712.1"
                     /translation="MLIHLVKKDVLIVKKYVLFILFLAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFIMVFIYCTLVY
                     WIENLLIPQMGTFDLTYILIVLLISSIIYGVYMPVQYKLGYETTKAFFVVIIMASSFV
                     LPLIIGHSNFEVPFIYQYSSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            12240..12974
                     /locus_tag="PC592_002763"
     CDS             12240..12974
                     /locus_tag="PC592_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4056713.1"
                     /translation="MNLTKGLDVLKISSNVFGEDKVMYIPVIYTEDEATLIDTGLPGQ
                     GDLIVDALNKSNTSFDKLKNIIITHHDIDHIGNVNYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIGDKMLSMLNVMGLGFKSSYTKVDVSLDNHEFLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQIDNGELKPVDVMHSNKQELKDAIKNISNYD
                     IEAIVFSHGGLYQENIIETLNNIIIE"
     gene            14006..15262
                     /locus_tag="PC592_002764"
     CDS             14006..15262
                     /locus_tag="PC592_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF4056714.1"
                     /translation="MITKFKTLIWIKILIRIKSVYKAYGGLFLLGIIGIPIGAIIGLI
                     DTVFGTVLLKITDIRETYPMYLIPFLSVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLIPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWIGKRLPIKNASSIFLV
                     TGMAAGFAGLFGTPIAAILFAMEVLVAGSLEYQSLFPAFIASFTASEVTKALGLEKFS
                     FALSSKVVFDLSIFWKFIALGIIFGMVGGAFAWCLKLSKRKICNRLKNPMIRIAIIGA
                     CISILFLLFDKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFVLTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYVFNMDKSIYSLQKISTKQ"
     gene            15305..15686
                     /locus_tag="PC592_002765"
                     /pseudo
     CDS             15305..15686
                     /locus_tag="PC592_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
     gene            15877..16257
                     /locus_tag="PC592_002766"
     CDS             15877..16257
                     /locus_tag="PC592_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4056715.1"
                     /translation="MYLKKLSKLELVIMKFIWNLDIKTNSCEIIDYMKEEHNLSEKVA
                     LKTLSKLSKKRFLYVQETDKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEDLTEEKIKSLENWVVNWEEACI"
BASE COUNT         6345 a         1815 c         2861 g         5824 t
ORIGIN      
        1 aataaatatt tttatagtag tagttaatta ttaataagga gtgttcaaaa tgcctagtat
       61 gattatggaa attgtaggag tactatttat agctattgga ttaatcttga cattcattga
      121 aataaaagga aatttccctt ctttttatgg ttttggtcaa aattctatag ggaaaaatgc
      181 tataggtatt atagcagcag gaattgcttt aattttcttt agaaatggca tagatagcat
      241 aggttctata gctacttatg gtatattttt agctatagaa cttgttgtaa tagttgcata
      301 tttcttaata agaaaaaaat ttactaaaga agataaacat ttaagaacta attaactaaa
      361 ttatctacta taaaattgga aaattaaaaa caaataaaag tttgttttta attatttaaa
      421 atccaaattt gattattttt gaagaaacta tgttctgtat aaaactggga tgtggtttct
      481 tttttatgta taaaataatt ttttagtaaa agttaaaaag tattttaaaa gatagatggt
      541 actattttga ttactatatt tgataattac atacaagata atatgaaaat tatgatgtct
      601 aaacccttta gagtcttgac aataaatttt agataataga taaagaattt tttaaaaatt
      661 taattatttg gagaaataat tctaatagta ttttgtattt agcttaacga ttcggagaaa
      721 taattctaat ggcattttgt atttaattta acgttttaga gtaaagttct aatggtattt
      781 tgtatttaac ctaataattc agagtaataa gtctaactgt attttgtatt taacttaatg
      841 atttggagta ataaggttaa ctatgttttt gtatctaatt taattattta catctatgag
      901 attgactagt ttttatatct atttaatata aatagtagac ctaatataaa aaccgttttt
      961 acagtaaaat tgaaaaatta gaaaaaagtt agatttgaaa gctaaaaaag ataactttat
     1021 tttgtatact atttttagaa aagaagtatt atgaattata ccatagagcc tactcaatta
     1081 aataaaatgt ataaagataa agctgttatt aataacatta atattcatgt aagaaaggaa
     1141 gtcatttacg gatttgtcgt acaaaataga gcaggtaaaa gtacagtgat gaaaatgttg
     1201 ttaaacctaa ctaagtcaaa ttctggagaa ataattatat tcggtaaaaa attagaagaa
     1261 actgattttg aaatgttaaa aaagattagt actattattg aaaatactta tttctatgag
     1321 aatttgactg ataaacagaa tcttgactta cattgtgaat atatgggcta ttataacaaa
     1381 gaacatatat cagagatatt gaaatgtgtc ggattgtcaa aacaatcaag caaaaaagtt
     1441 tcaaaatact ttttaggtat aaaacaatgt cttttaatag ctagagcaat tcttactaag
     1501 ccagaattat tgattcttga tgaatctata aatgcactcg acccagaggg aataagagaa
     1561 atgcgagaat tattcaataa gttaaataca gattatataa caactatatt tacttctagt
     1621 catattcttt cagaggtaga ataaattgcg gatactattg gcattattca agatggtaaa
     1681 cttattaaag aaatttctat gtcagatata cacaaatatc aaacagatta tgttgaagta
     1741 gatgtagata atgtggagct tgttggatac ttgttagaaa aataatcttc ctataaaaat
     1801 tgtaccttga ggtagtgagg acttgtatag aaactcctta aattcttata gtataggtaa
     1861 ttatgtccct ttaattgaat atttattaag tttagaagat tttagagaag tatataaaat
     1921 gttatggaaa taattgtttg tagcaaaaaa atatgttttt tatacaatta tgtttttact
     1981 tatagtattt aatgctaatt tcttaatcat tcttagtttg aactataccc actattttaa
     2041 ccatataaaa tagtgggtat agtttaacta gttatttata actattttta catatcttaa
     2101 ttgttcccta atagggggat agtccataaa actaaaagtg gtttttaatt ttatcattta
     2161 taacttgcta ttacctcaaa aaaatgctta tcattataat tttcataaaa gttacctatt
     2221 tttttcaact ttttttcaac tagctaaatc aattctatta gtgttaatct tttatgtttc
     2281 aaacttataa tacaagaaaa taaaaaataa aaaattttaa attttttatt tattgcgaaa
     2341 aaaataaaaa ggtgttatac tttttgtaac atattattcc aattattaag agatagtaag
     2401 catttatagt ttaatttgta gtacaatagc ttaattggca gtacaatgat ttaatccata
     2461 gtacaatagc atgacttgta gtacaatggt tcaaactata gtacaataac gtgatttgca
     2521 gtatgatggt ttaagctata gtacaatagc ttgttttgta gtacaatgat ttaatccata
     2581 gtacaatagc atgacttata gtacaatggt ttaaactgta gtacaataac ttgacttgca
     2641 gtacaataat ttaatctata gtccaaaagt actatcaaat aagaatttct actttaaaaa
     2701 cgttactaaa agtaattaag gtcaagtagt tcaatataat atggcaaaag aatagaaata
     2761 aggtgagagt agtgaaagta aagtcaaatt tagatgaaat tttatatcat aagattattg
     2821 aaagtcttat tcgtggtgaa tactctgtag gtcaaaaaat attactaaat gacctttgtg
     2881 aaaaatttga agtaagcaga acaccagttg tacaagcagt aaaaatgtta aataaagatg
     2941 gtgtgcttac tattatgaca aatggtaaag tgtacgtacc agagtatgaa tatgatatgg
     3001 taaaacaagt ttgtgaaacg agaacactga ttgaaacata cgctttagaa aaaatgatgc
     3061 aagaaaagga agacgttttt caacaaaagt tagatgtgat aaaaagatac tctgataaat
     3121 gtgaggagta ctatcgtcag gaaaaatctg tagaacttgc actagcagat ttggaattac
     3181 ataaagccat tgtagaaggg gcaaataatg agattttaaa tgatgtatat gttggtatac
     3241 aaggaagatt tatagtagtg aactatttaa ttcgaccatt aaaaaatcgt aattatgaag
     3301 gaacagtaca agaccatttt gaaatattaa aattcattga agacagagat acaaaaaaag
     3361 cagtagataa attaagaaat catattcaag gaactattaa aagattctgt gaagatgaat
     3421 aataagtttt gaagttacta tatatactta tctattaagt tgctaaatgt agtctaagta
     3481 taatctaaat gtagtttaaa cataatctaa atacagtgta aataagtcta agtataaatt
     3541 aaatatagat taagtatgga ttaagtatgg attaagtacc aattaagcat gaattaaata
     3601 tactttaaat tacaaatatt ataaggaagc cataaggctt cctaaaaaaa taacctttat
     3661 aaaatttttt attttaaatt taaaattttt tattttaaat ttaaaataaa aaatgaaaga
     3721 ggtggtaaga agtttgaaaa aaattactaa agaaaggata gaaaacacta tgaaaaagct
     3781 atttacaagt gaaacatttt tggaatatca atttataagt gattgccaga tatcaccaga
     3841 tggaggatat acagcattta ttgtaaaaaa agctgatatc aaagagaatg cttacacaag
     3901 ccaagtttat atactaaaca ataaaagtgg agaattaaaa caaataacgt ctataaactc
     3961 tgttggagca tatgcctggg aagatgaaaa tactatcttg ttccctgctt tacgaaatga
     4021 gaaagtaaaa gaagctgtca aagatggtaa acaatgtatg agctactatg ctttatcttt
     4081 aaatggtgga gaagcagaag aactttttag actccctatc aaaggtggta aattgaaccc
     4141 tataggaaaa ggtttgtatg cagttattga ttcttatgat aacgaccgac ctattgtaga
     4201 gggattgtca gaagaagaac aacagaaaaa aataaatgct tataacaaca gacactatga
     4261 acatttcaaa gaaattcctt atgctgttaa tggggaaggg tatgttagta gaaaaagaaa
     4321 acgcttatat ctatatgaca gtaatataaa tgagttgaag gcaattacag cacctatgtt
     4381 taatgttgta ggtatgaaaa taagtgatgg aaaaatctta tatgtagggc aagagtttaa
     4441 agatgtaaaa ggtttgaaaa atggagtcta tgtatttgat acaaacacaa acacaaatgt
     4501 ttgtatatta gaaaaagata agtatattgt aaaaggtttt gaattatatc aaaatcaagt
     4561 gatactaaac ctaactgatg ctttatctta tggaaatgga gaaaacggag atttttatac
     4621 tattgatatt gatacaaaag aaatgaaact tctttcagag catcaacatc attgtattgg
     4681 aaatacagta acatctgatg ttaaaatggg tgttggtcag acaacaaagg tagacggaga
     4741 atatatttat tacacttcta cagtagatat ggattgtatt attgaaagaa tacatattcc
     4801 aacaggaaaa caagaaaaag taacacagac aggttcagtt gattttatag atgtaaaaga
     4861 tggcaatatt gtatgtgtag cttttttagg agatagatta ccagaagttt atacggtaga
     4921 gaatggaaca ctgtgcaaga aaacacattt aaatgaccat attttagagg aatataaaat
     4981 ttctgaacca gaatacatag agtcaaaagg aagttctaaa tgggaaatac aaggctatgt
     5041 atataaacca gtagattatg aagttgggaa aaaatatcca gctgtattag tgattcatgg
     5101 aggaccgaga ttgacatatg gaccatattt tatgcatgag atgcaggtat ttgcaagtgc
     5161 aggttacttt gtattcttct gtaacccaag ggggtctgaa ggtcgtggca atgcctttgc
     5221 agatattagg aaacagtttg gagatattga ttatatagat tttatggaat ttacagatac
     5281 tgtacttgaa aaatatacag acattgataa aacaaaattg gccgtagaag gtggaagtta
     5341 tggtggattt atgacgaatt ggataattgg tcatacaaac cgttttgctg ttgcttgtgc
     5401 tcagcgctct attgcaaact ggagtggcat ggagggtaca acagacattg gttattattt
     5461 ctgcaaagga caaacaggtg cttcacatat ggaaaaccac gagcttcaat ggaaacagtc
     5521 acctcttgct tatgctgata aatgtgttac accgacttta tttttacatg gtgaaaaaga
     5581 ctatagatgc tatatgcaag aagcattcca gatgttttca gcattgaaaa ttcatggatg
     5641 tcctacaaaa ctttgtctat ttgaagggga aaaccatgaa ctgtctcgtt ctggtagacc
     5701 aaaacaaaag ctacaaagat tagttgaaat gctagattgg ttttctgtgt acataaaaaa
     5761 agataacata ggacagtaga gaaaggagaa tataaaaatg gaaaaaataa agattgaaaa
     5821 ttctgatatt tttgaatata tattccctca tgatatttct tgttcacctg atggaaagca
     5881 tattgcttat attatatcaa atatcaatga ggaaaaagac tgctatgaac atgacttata
     5941 tgtgatggac atcaaaacag aaaaacaaat acatatgact caaacaaaag atgtaacatc
     6001 atttagttgg atttctaata cagaactact ttttacatct aaaagaaata agccaaaagc
     6061 aggtacaaca gatttttaca ctatttctat agaaggagga gaagcaaaaa aagcattttc
     6121 tatcccaaaa gcttgtagcg tacctgtatc acttggaaat aaattgtggt tattgacaac
     6181 aaaaaatcca acagattcta aaaaatcaga gccagatagg gcagtagagg gtatagacta
     6241 ttggacattt acagataaac cttttataag agatggagaa aacttttctc aaagaagacg
     6301 tgtaacatta gaactatatc aagaaggtga aaatacaaca aaagccatta caccaaaatt
     6361 ttgtgaagtg gcgggtatag atgtttcttc tgataaaaaa agaattttat atgttggtca
     6421 gatttatgaa gattgtgcaa ctcctttttc tgggctttgg gagtaccata tagaaagtgg
     6481 tgaaacaaag gaacttgtac cacaaggaaa ataccaaata agtttggcaa aatatattgg
     6541 cgaaaataaa gtaatgttgc aagcttcaac attagaccgt tctattacac aaaatcatga
     6601 tatttttata cttgatttga gcactagtga aataagtatg attgctagtc tagatggtat
     6661 gtatgctaca ttactggatg tagatgcagt atatggtggt ggacgtagta ataaagttat
     6721 aggagataaa ttcattggtg caaggatttg cagaactatg acagagtttg atgagtttga
     6781 tacaaataca ggtaatatac gtattatcac aaaagtagat gcttttacat cttttgatat
     6841 ttatgataac actatgtata cagtaatgtt gaaagattat gagttggcag aaatatatag
     6901 cattgatatg actacaggta caatgaaaaa aatgactgct ttttctaaac cctatttaga
     6961 cactcataag gtttcattgc ctgaaaaatt gacgtttata gcaaaaaata aagaagaagt
     7021 tgatggtttt gttataccac ctatagatgc taaagaaggc gaaaaatatc ctgctgtatt
     7081 gttcattcat ggtggaccta aatgggcata tggctatatg tttacacacc taaagcagtg
     7141 tgtaacatca aagggaatgt atgtgattta ttgtaaccct catggcggtg atggctatgg
     7201 tgaaaaattc ctggaaatgg tagaaagatg gggatatgtt gattatgaac atcttatgga
     7261 gtttgtagat atttgtattg aaaaatatcc tggaattgat gcagaacgct taggtgttgc
     7321 aggaggaagt tatggcggtt atatgacaaa ctggataatt ggtcatacag accgtttcaa
     7381 ggcagctgct tctcaaagag gtattagtaa cttgattaca gcttctttaa ttattgactt
     7441 tggggataga attatgaagc agacttgtgg agataagaca ccttggaatc atgaggaggt
     7501 tctttggaat cattcaccta ttaagtatgt gaaaaatgtg aaaacaccaa cattgttctt
     7561 gcatagtgat agggattata gatgttttat gggggatact ttccaaatgt ttacagcatt
     7621 aaaacagctt ggtgtagata ccgaaatgta tttgttccac ggagatacac atggattgtc
     7681 tagaaatgga agaccatcta atagaatcgt acgtgtaaat gctattgtag attggtttga
     7741 aagatattta taataagggg gttattctat gagtgatatg ttattatggt ttagtgtagt
     7801 attagtttta tttgctattg gagatttgat tgcaagtaaa acaaaagcaa aagtatcagc
     7861 tgtatttgtt acattacttt tatttttaat tctctttgtc acaaaagcaa taccagctga
     7921 tattattgag aaagcaggta tgacctcagc agctagttgg agtgttccaa tgattatgtt
     7981 tagtatggga acaatgttga atgttaaaca atttatagac gaatggagaa ccgtattgac
     8041 agcatggctt ggaattgtag cagttattgt ttgtgtctca ttatgtattc ctttgtttgg
     8101 aaaatcaaca gtattaacaa gtataccagt tataaatgga gctttacctg ctactactat
     8161 tatgacacaa gcagcattag aaaaaggatt aacacttgca gcagctacag caacagttgt
     8221 atttgcaatt cagaagttta ttggtacacc aatagcttca agagcagcac tacaagaggc
     8281 aaaccgtctt ttagtagaat atcatgaagc aaaatcaaaa ggcattgatt tagcaaatgt
     8341 tgatactgat aagaaagaag cagagagtac agggacaaaa gtaaaacaag ctttctgtga
     8401 aaaatatgat aaatattact ctacaaatgt ctgtatattt tttatagcac tattctctta
     8461 tctaggatat gagctttcag agattattca tgtaaattat tctattgtat gtcttgttgt
     8521 tggtgttctt gtaacacgta ttggtattgt gccaaaagat attttggaaa aaggaaaaat
     8581 caagggattt atcaacatgg ttgtgtttgc agctgttatt ccttctttag caaaagtctc
     8641 tttgacagac ttaattagtc tttttgtacc aattgtaggt atgtttgcag cctctatcat
     8701 tggtatattc cttatgatga aggtattacc aggttggaaa attattggtt ctaaacctct
     8761 tgcttttgga gtaggcttct gtcagatgtt gggattccca actacatatt taatttcaaa
     8821 tgaagtatgt aatgctgttg gagaaactga agaagaaaga gcatatttga tgtctaaaat
     8881 tatgcctaag ctggtagttg gtggtatggc ttgtatgatt tctattgtag tagcaggtct
     8941 tatggtacca atgttgtaga tagattttat agttaaaaaa gtaaatttaa tttatagtag
     9001 aatataaaaa aagaagtgcc ttaaagtgaa ctcttagtcc ataaggcact tttttgtatg
     9061 aatttgaata tattttaatc attttaatat tgataaagag acttatatct agtttgagat
     9121 aagtcttttt aattattaaa gttatttttt atcttatttg cataatttta tacttttcaa
     9181 gtatacaatt ttatttttaa tataactttt ttaattaatt tccaaattat ataagcataa
     9241 catatgcttt taacagcttt actaatagat aaggtatagt taaatttagt aatgaaaagt
     9301 ttaacttata ttgagtgtaa atctttgtat tgacaaaaaa agtgtactaa gtgtatagtg
     9361 tgtatataat aacatcacat tgaaagtgat aaaaaggagg tgataaaaaa tgaaagtcct
     9421 aatttctaac acatcagata agccattata tcaacaaatt aaagagcaaa ttaaagaagc
     9481 catatttact gaagaactaa aagaagggga tgcaatgccc tccataagaa attttgctag
     9541 tgatttaaaa gttagcattt taactattag acgagtgtat gaagaacttg agaatgaagg
     9601 ctttcttaca cgtcaagttg gaatagggac ctttatttca actggaaatt tagaaatatt
     9661 aagagattcg aagagacgta tagttgaaca aaaaatggca gatatgataa aagatgcaaa
     9721 agcactaggg attacacaga tagagttaca agaaatgatg gatattctat atgaggagga
     9781 ttaatatgga aaatatttta gaagtttata acttaaataa gacttatacc gatttttcat
     9841 tatctaatat aagctttgcg ttaccagaag attgcataac tggatttata ggtgttaatg
     9901 gagcagggaa aacaacaaca atccgttcga tattggatgt tataaagcgc gatagtggaa
     9961 aaataaaaat ctttggtaaa gacttcaatg gaaacgagaa ggaattaaaa aatagaattg
    10021 gggttgtctt tgatgattca tatttttatg atgagttgtc aatggcagaa atgaagagta
    10081 ttattgcacc ttcatatgat aattggtgcg aagaagatta tcaaaaaaat atgaagcatt
    10141 ttaatcttaa tccaaaacaa aagattgata cactttcaaa aggaatgaaa atgaaatttg
    10201 ctttagcatt agcattatca cataaagctg aatttttaat tatggatgaa cctacaagtg
    10261 gcttagaccc attaatccga agtcagatac ttgacatact aacagaatac atgaagaaat
    10321 gtggtcgtgg tgttttcttt tccactcata taacatctga tttagacaaa atagcagata
    10381 tgattgttat gattgataat gggcgtatta tattagaacg tgaaaaagat actctcttgg
    10441 aagaacatag aaaagtaaaa ggggatatta agttcctaaa tgatgaaatc aaaaaattat
    10501 ttttaaattt ggaaattaca ggttatggtt ttatagggat tacctcaaaa attaatgaag
    10561 ttcaaaaaaa tatgccagat attttgatag agcgtcctac aattgaagat attatgcttg
    10621 cgtatattga aaggagagag taattatgtt gattcattta gttaaaaaag atgttctgat
    10681 tgtaaaaaaa tatgtattgt ttatattatt tcttgctata ggaataccat tatttatatt
    10741 atggcgttta cctccgtttg cacaaatatt gggatttgta ctgtcaatta tattttcaga
    10801 atttatgctg tgccagtatc tcttattaaa ggagagtcaa tattcaaaag catctgtatt
    10861 actttgttca actccttatc ctagacgtgg cttagttcaa tctaagtatg ttttatttat
    10921 aatggtattt atctattgta cattagttta ctggattgaa aatttactta ttccacaaat
    10981 gggaactttt gacttaacat atattttgat tgttttacta ataagttcta ttatttatgg
    11041 agtttatatg cctgttcaat ataaattagg atatgaaaca acaaaagcct tttttgtggt
    11101 gataatcatg gcttcatcat ttgtattacc attaattata ggtcacagca attttgaagt
    11161 tccatttata tatcagtatt catccatgat agtgaatatt gtattgttcc ttttaagctt
    11221 aattatactg ttagcttcaa tgtttatttc tattaaaatt tttagtaata aggaacttgt
    11281 ataaggtaag gggaaatttt atatgccaca tttgccagat tgggctgttt tactttgtat
    11341 cttacttcca atagtatata aagcttgtca gatatttaaa agtaaaaaat agagtacata
    11401 tgtatattga catttttatt gagtgaagtt agatgttatg aatttagaag gttacttgaa
    11461 aataaagtta cttggtgtgt gagagtaaca tcataatatt atagattata tgtttcttgt
    11521 gaatcaattt gtattctttg atagaggatg tcaagtaatt ttatttttca ttgattattt
    11581 gtcaattatg ggtataattg tgtattatct ttcaaggtgt ttttgaaaat ttatatcgtc
    11641 aaaatataaa tctaaggact cctttaaata aagtttgtta atcttagaaa actaataaaa
    11701 agtagaaaac taataaaaat aggaaatgaa taataagagg ctgtctaaaa atagagataa
    11761 gcttcttttt cattgttaaa ataatgaaaa tacagttgat ttcatataaa aagagtactt
    11821 tatgaactaa aagtttattt tgaacccaat ttttattaaa caatatttta ttcttctcaa
    11881 atagtcatct atatacagta ttgtattttt tacttattta taatttattt tcttattata
    11941 gtttttctat atttatattt tctatattac tttacgttta acaacgtaca aattattaaa
    12001 aataaaatag ttattagaaa aaaataaaag taattgcaaa gattgcaatt acttacttct
    12061 atattaatta ctataccata aaataacaaa aaaatcaagt cgagtaatcc ctcaacttaa
    12121 gtgatatact aggtattaat aatttttaat taaaaaaata taactagagg caaatctata
    12181 ttttctcaat ttctttaatt aaattgacct ctaattaagt aattataagg agaaaaatta
    12241 tgaacttaac aaagggatta gatgttttaa aaatttcatc aaatgtattt ggtgaagata
    12301 aagttatgta tattcctgta atctacacag aagatgaagc aacgcttatt gacacaggtc
    12361 ttccaggtca aggtgattta atagttgatg ctcttaataa aagtaacaca agctttgaca
    12421 agttaaaaaa tataataatc actcatcatg atatagacca tataggaaac gtaaattatc
    12481 taagagaaaa atctaagaat aatatcaaag tatacgcata caaaagtgaa gttagctata
    12541 taacaggaga agaaactcct tttaaacttt atatgttaga acaaatggta gataagattg
    12601 gtgataagat gcttagtatg ctaaatgtta tgggacttgg atttaaatca tcatatacca
    12661 aagtagatgt atcattagat aatcatgaat ttttgaatct aggtgaggaa atagaagtta
    12721 tacatacagg aggtcatact agaggtcata tatgtcttta tttaaaagag tctaaagtac
    12781 ttattgctgg agatttgcta cagatagata atggagaact taagcctgtt gatgtaatgc
    12841 acagcaacaa acaagagtta aaagatgcta ttaaaaatat aagtaattat gatatagaag
    12901 cgatagtttt tagtcatggt ggattatatc aagaaaatat aattgaaaca ttgaacaata
    12961 taattattga gtagtattta ttatatgatt ttaataatct acaataattt cttaaattac
    13021 ataacgttgt atttaggtgt gaaaaattaa aatcaaatat aaataataaa aattagattg
    13081 tatcaataaa aatatcctta taatttattt atttggattc taaggatatt aaatctatta
    13141 caagtatata tatagatgta gttaattaca ctacaagtta aagaatctaa accaacaatt
    13201 aaaagaaatc aaaatataaa tccaatcaat taaattcttg acatatataa attgttttta
    13261 tccttttttg ggtgtcgata ataattttta aaatttaatg tcaagtaaac acaataaaac
    13321 acagagctta ttctaaaatt atggttttta ttttatgtat acagttatag tattgcaagt
    13381 agtttacaaa atggtctata tgtgtcaaat tgaaagtctt gtaatactta agttgaaaaa
    13441 tatttaacat catagtataa tagggtagaa aatactttaa atcaacttta gaatacaata
    13501 ttataaataa tcactcagat agatattata aaaataaaat aaattctgga aaaggcataa
    13561 catggatgta ctggataatt tagatgataa attgtaaatt gtattattta caacataaag
    13621 aatataacat aagggataag attgacatat aaaaaatgat ataataatta tgggaatgag
    13681 gttctccctt ggatgataat atcctaaact gccaatgagc tgatgacttc tatgatatca
    13741 tagatgccac cagctttttt tgttgtttaa attgataaaa tggaggtgaa atagttacta
    13801 aattcttatt gtttgaattt gaataaatat ttaaaagata gaaaaaatgg cattttatat
    13861 gctaattact ttgttagtat agagattaag agtgtggcta tatgctatta attaaaaaaa
    13921 acaattatta tagaagccac attgcctata gttgatgcaa taatattttc aaaatatctt
    13981 ataaagcagg tagaaaggaa gtaaaatgat aacaaaattt aaaactttaa tatggattaa
    14041 aatattaata agaattaaaa gtgtttataa agcatatgga ggactatttt tgttaggaat
    14101 tataggtata ccaattggtg caattatagg tcttatagac actgtatttg gaacagttct
    14161 tctaaaaatt acagatatta gagaaacata tccaatgtat ttgataccat ttttatcagt
    14221 agtaggtgtt gttattgctt actgttattt taagtttgga ggaaagagta gtaaaggaat
    14281 gaatctaata tttgaggtag ggcatggaga agaagaaatt attcctttaa gattaattcc
    14341 atttatcata tcaggtacat ggttaaccca tttatttggt ggtagtgcag gacgagaagg
    14401 agttgctgtt cagattggtg ctactttttc acattggata ggcaagaggt tgcctataaa
    14461 aaatgcttct agtatttttc tagtaactgg tatggcagct ggttttgcag gattatttgg
    14521 gacaccaata gcagcaatcc tttttgctat ggaggttttg gtagctggtt cactggagta
    14581 tcaatcgctt tttcctgcat ttattgcttc ttttacagca agtgaagtaa caaaagcttt
    14641 aggattagag aaattttctt ttgcactttc ttctaaagtt gtatttgact tatcaatatt
    14701 ttggaagttt attgctttag gaattatttt tggaatggtt ggaggagcat ttgcatggtg
    14761 tcttaaattg tcaaaaagaa aaatatgtaa tagattaaaa aatcctatga taaggattgc
    14821 tattattgga gcatgtatta gcatattatt ccttttattt gataaaggga gatattctgg
    14881 tttagggacg aatctaattc aaaatagttt ttatggtgga gaaatttatt catttgactg
    14941 gctgttaaag tttgtactta caatactgac tttgtcggca ggttttcaag ggggagaggt
    15001 tacacctttg ttttctattg gagctagtct tggtgtatta ctagcaggat tttttaattt
    15061 accaattgaa ttagttgcag cacttggcta tgctagtgtc tttggtagtg ctacaaatac
    15121 tttttttgca cctgtattta taggagcaga agtttttgga tacagctatt tgccttattt
    15181 ctttgtagta tgcgctattt catacgtatt taatatggat aaatctattt attcgctaca
    15241 aaaaatttca acaaaacaat aaaaaaacaa cataatatgt taatggaatc tgtttagcag
    15301 tatttttaag aaagtccata tgagagattc tgctaaaagt gttttacttt tgggtatatt
    15361 atttttaatg ataagtttgg agaatgattt agatggaatt gtgtcatttt ccggattatt
    15421 agcagttatg agtattctta tgtcctatta agacaaaatt gatattaaaa gaaatattat
    15481 tctgtatgat gggatatatt ccaaaagcta aagtacagat agcaatagga agtgtaccac
    15541 ttgcaatgga gatggtatct gggcaattta ttttgacatt agcagttcta tctatactta
    15601 taactgtgcc tcttggaact tttggaattg atacaactta taaaaaatta ttaacatctg
    15661 taaaaggtga cagtaagcaa aaataaagat tattttaagt ggtcaatttt aaaaaaagaa
    15721 ccatattatg aatacaatgt cagaaaatca tttgagagat taaagaagat agaagttcag
    15781 tatggatttt aaggtatgtg atgattatta gaattgattt tgtgaaatta ttattgtaat
    15841 atttaactat atagataaag aagcggagtg ataactatgt atttaaaaaa attatcgaaa
    15901 ttagagttag ttattatgaa atttatttgg aatttagata taaaaaccaa ttcatgtgag
    15961 attattgatt atatgaaaga agagcataat ttatcagaaa aagtagcttt aaaaacttta
    16021 tcaaaattat caaagaaaag attcttatat gttcaagaaa cagacaaatg tatgtattat
    16081 acagttgcaa taaaagaaaa ggcatatctt gagtttatat cgagaaatgt gcaaaatctt
    16141 ttgaagaata attttataag gaatttatta gtgtcatttc atgaggagga tttaacagag
    16201 gaaaagataa aatcgttaga aaactgggta gtaaattggg aggaagcttg tatataatgt
    16261 tattattttt attacaattt agataatttt ggttttgtaa gctctgcaac tatttttaga
    16321 tggttgcaga gcttattttt atttttaatt tccttaagta atacttaaaa gtaaacgtat
    16381 ttatatttac taacttcaat cacttctaat acttacgtta ctttttaaaa gtattttgat
    16441 atgtcatctc tatagtaatc taaaacttgt ttctattatt tatatgaagt ttttaattat
    16501 tagagatgat tatatttaaa ataaattatc atataaatta tgctaactta ttagacttgt
    16561 atttaaaaca tatttggctt aaatttaaaa aattcaagtt ttgcatagac taaaaaaagt
    16621 ttttatgaat gatatatata atattcattc atttgattaa aaatagaaaa atattaaata
    16681 attctactgc ggtagtgtgt taaaaaaaag aataaaaaat gttaataaat aaacaagaat
    16741 tatattaaga gaagggaatt ttctaaaata caaaaaggta tctagatttc ataaaaaata
    16801 ttattttgct cttaaaaata tttagattgg aaaaatttta attta
//
LOCUS       DAMKOJ010000074        16686 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000074 DAMKOJ010000000
VERSION     DAMKOJ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.080"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            82..1035
                     /locus_tag="PC592_002767"
     CDS             82..1035
                     /locus_tag="PC592_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF4056716.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RVPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFMFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            1025..1981
                     /locus_tag="PC592_002768"
     CDS             1025..1981
                     /locus_tag="PC592_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF4056717.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFVIYGIDINHLEYALSQRIPKI
                     FAMILGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAIMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKVVKKMIILIAILVSISTALIGPMTFLGLLLANIAREIFKTYKHTYLILGSMLIGM
                     ITLITGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            1978..2733
                     /locus_tag="PC592_002769"
     CDS             1978..2733
                     /locus_tag="PC592_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4056718.1"
                     /translation="MIEIKNIFKKYKNKNVVDDVSFNIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMDFKIKNINGNRICIYF"
     gene            2825..3790
                     /locus_tag="PC592_002770"
     CDS             2825..3790
                     /locus_tag="PC592_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4056719.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKNNESKTSENSNNTIKIIH
                     NLGETDVKLNPKKVVVFDYSALDTMDTLGVAENLVGLPKASLPASLEKYKDEKYADLG
                     GLKEPDLEGIKSTNPDLIIINGRQEDFYEQLSKIAPTISTSKDDKEYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFKNKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDIKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            4244..6103
                     /locus_tag="PC592_002771"
     CDS             4244..6103
                     /locus_tag="PC592_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4056720.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHKPNDELIEYIDEILQELITGHGNYGLVLTDCNKYNEDLLLLEKKW
                     EDLNSEIKKVRMKEPNNQLLSISEEFFSLANDTVFEIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMIKLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICMHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YIDKEDLVVRQRIVDSELINTTNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHNQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQNHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDALKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIEYEEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS"
     gene            complement(6303..6902)
                     /locus_tag="PC592_002772"
     CDS             complement(6303..6902)
                     /locus_tag="PC592_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF4056721.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNAQGENLRIN
                     GNKIKEIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(7005..7802)
                     /locus_tag="PC592_002773"
     CDS             complement(7005..7802)
                     /locus_tag="PC592_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF4056722.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(7915..8020)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(8112..9098)
                     /locus_tag="PC592_002774"
     CDS             complement(8112..9098)
                     /locus_tag="PC592_002774"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF4056723.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMNYLSKTNTDNTNYCLSELD
                     IEQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVSFVENKLIGIRHEENALRNTLNSIEINDYFLGADTDILVSGILGVK"
     gene            9582..11312
                     /locus_tag="PC592_002775"
     CDS             9582..11312
                     /locus_tag="PC592_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF4056724.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIIISALLLKEFGPMRKAEIKSRSRKIDI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGEDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVIKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKR
                     VDEAEIELVE"
     gene            11422..11502
                     /locus_tag="PC592_002776"
     tRNA            11422..11502
                     /locus_tag="PC592_002776"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11456..11458,aa:Leu,seq:tag)
     regulatory      12281..12385
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12595..15069
                     /gene="gcvPA"
                     /locus_tag="PC592_002777"
     CDS             12595..15069
                     /gene="gcvPA"
                     /locus_tag="PC592_002777"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDF4056725.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHDMVRK
                     SAGIFDVSHMGEVQIKGVESEKFIQNLVTNDISTLNINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSERYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSVKVCGCPCLVSRTGYTGEDGFEIYCENKYAEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPVEGGLSIFVKTNKESFIGKSILSK
                     EKENGAKRKLVGFEMQGKGMPRNGYDIRIGDKIVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIAKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATSAIEACIMAMNQTRKNKIVVSKTTHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDTEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAIQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            15069..16526
                     /gene="gcvPB"
                     /locus_tag="PC592_002778"
     CDS             15069..16526
                     /gene="gcvPB"
                     /locus_tag="PC592_002778"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDF4056726.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQNMIRKSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLSEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGNMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVSFLPIPVIEKREDKYILNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIDAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         6418 a         1900 c         2725 g         5643 t
ORIGIN      
        1 ataattatta ttgataaact attgaagtga aaatgataat aattttcatt ttaattaata
       61 aaagattttt aaggagggag aatgaaaaaa aggtatttag tcataggaat aataatttta
      121 tcttattttt ctttatttat aggagctgaa gatataaata taatgcatat atttgcaaaa
      181 aatcaacata agcttatgat atttatcatg agtagagtac caagattaat aagtatattg
      241 attgctggtg taggaatgag catagcaggt cttataatgc aacagataag taaaaataaa
      301 tttgtatcac ctacaacagg agctacaata gacgcagctc aatttgggat agtgatatgt
      361 atgcttttag taccaactgc ctctattttt acaaagacaa taatagcatt tgtattttct
      421 cttgtaggga cttttatgtt tatgaaaata ataggtaagt tacaatttaa aaatataatc
      481 tttgtaccat tagtaggtat aatgtttgga aatataatag gttctatgac agattttata
      541 gcatataaat acgatttgag tcaaaatgtt agctcttgga tgcagggtga cttttctatg
      601 atacttaaag gaaattatga gatattatat ataacaatac cccttataat actagcatat
      661 atttatgcaa acaaatttac tgttgttggt atgggtatgg attttgcaac aaacttaggt
      721 cttagttaca aaagaattgt caatataggt ctgataatag tagcacttgt tacagtatgt
      781 gtagttgtta cagctggtaa tatacctttt ataggtctaa tagttccaaa tatcgtatcc
      841 ttatatatgg gcgataatat aagagcaagt atatggtata caggtttact tggagctata
      901 tttgtactta tatgtgatat ttttggaaga attattattt atccatatga aatatctata
      961 ggacttacag ttggagttat aggaagtata ctattccttt atttaatatt aaggaggaat
     1021 gtaaatgaag cttagtctca atcaaaaaat ttactttgta agtatattac tattcatatc
     1081 aatagcactt tttgtaattt atggaataga tataaatcat ttagaatatg cattatcaca
     1141 aagaatacca aaaatatttg ctatgatatt gggtggagga tgtatagcat ttactactgt
     1201 agtgtttcaa acaattacaa acaatcaaat attaacacca agtgtactag gtttagattc
     1261 attatatgta atgattcaaa ctataatagt atttatattt ggttcaagta gtagtctgat
     1321 tataaatgaa aattataatt ttattattaa tgtagctatt atgattggag cttcattatt
     1381 attatataag atgctatttg aaaaaaataa aaataatatt ttctttttaa tcctagtagg
     1441 aatgatattt ggaactttat ttaaaagtgc aacaacattt attcaagtaa tgatagaccc
     1501 aaatgaattt ttagctttgc aaactagcat aatggccagt ttaaacaata taaacactaa
     1561 tgtattgtta atagcattta taataattat tgccataata ccttttatat atgatgaaat
     1621 aaagtattta gatgtattgt cattaggtaa agagcaagca attaatttag gtgtagattt
     1681 tgataaagta gttaaaaaaa tgataatatt aatagcaatt ttagtctcaa tatcaacagc
     1741 acttattgga cctatgacat ttttaggact tttacttgcc aatatagcca gagaaatttt
     1801 taaaacatat aaacatacat acttgatttt gggctctatg ttgataggaa tgattacatt
     1861 gataacaggt caatttttta tacaacatgt atttaaattt gatacaactt taagtgtagt
     1921 aataaatttt ataggaggaa tttactttat tcaattacta ttaaaggggg caaatagatg
     1981 atagagataa aaaatatatt taaaaaatat aagaataaaa atgttgtaga tgatgtctct
     2041 tttaatatag aaaaaggaaa gataacatct tttataggac caaatggagc tgggaaaagc
     2101 acagtactat caatagttac aaggcttata ggaggtgatg gtggagaagt aataatagaa
     2161 ggaaaaagct tgactaatta tagcaataaa gaattggcaa aaaaaatagc tattcttaag
     2221 caatctaaca atataacttt aaagcttaca ataagagaat tagttggatt tggaagattt
     2281 ccatatagtg aaggtaatct aactaaagag gatgaaaatt atattgatga agcaatagaa
     2341 tatatgaaat tgactgatat acaacacaag tatttagatg aattaagtgg aggtcaaaga
     2401 caaagagctt atatagcaat ggtaatagct caagatacag agtacatatt gcttgatgaa
     2461 ccactcaaca atttggatat gaaccattca gtacagatga tgaaagtact tagaggtctt
     2521 tgtgatgagt tagataagac tatagtatta gtaatgcatg atataaattt tgcatcatgt
     2581 tattcagata atatagttgc attaaaaaat ggaaaagttg aaaaagtagg tcgtacagat
     2641 gagatagtaa atgaaaaagt tttagaagat atttatgaga tggattttaa aattaagaat
     2701 ataaatggaa atcgaatttg tatttatttt taaaatatta tatataaaaa taaacttgct
     2761 atattatttt ttataaaatt tttaaagtaa aataaagatt aatagaaaag aggaaaatat
     2821 tgatatgaat aaaaaagcag cgatagtagc agcagtagct attataggtt tagtgacagt
     2881 gtttgcatta ggtggaagta aaaataatga gtcgaaaaca tcagaaaatt caaataatac
     2941 tataaagata attcataact tgggagaaac agatgtaaaa ttaaatccta aaaaggtagt
     3001 agtatttgat tattcggctc tagatacaat ggatacatta ggtgtagctg agaatttagt
     3061 aggacttcca aaggcgagtt taccagcatc cttagaaaaa tataaggatg agaagtatgc
     3121 agatttagga ggtttaaaag aaccagattt agaaggtata aagtcaacaa atccagattt
     3181 aattataata aatggaagac aagaagattt ttatgagcaa ttgtcaaaaa tagcaccaac
     3241 aataagcaca agtaaagatg ataaggagta cttagaatct gttaaaaata atatagataa
     3301 aatagcaaaa atatttggag tagaagaaaa agcaaatcaa gaatttagta aaattgaaaa
     3361 gaaaatagaa actttgaata aaaaagtaac agataaaaat ttaaatgctt taactataat
     3421 ggtgaatgaa ggtaatttaa gtgtatttgg tgaagaatca agatttagta tattatacaa
     3481 tagttttgga tttaaaaata aagataaaaa tataaaagaa tcaagtcatg gacaaaatat
     3541 tacttttgag tatatagcta aacaaaatcc agaagttatg ttcgttatag atagaggaat
     3601 agctactggt agtgatataa aagagagctc aactgcaaaa tctgttttga acaatgatat
     3661 aataaaatct atggatgcat ataaaaatga taatataata tatttagatt caccaacatg
     3721 gtatgtaaat gatggtggtc taacatcttt aaataaaatg atagatgatg cttcaaaagc
     3781 ggtgaattaa taatctgata taatcaaaat gtgtttttta tgaaatgatt atcaaataaa
     3841 ctaggagttc ttaagaactc ctagtttatt ttttgcataa taaagatata gtttaaaaaa
     3901 taatattatt tacaataaga taaatttatt caaaatctaa taaaatatga agttatacta
     3961 gacaaaaaga ataattctta aatataatta aattatatgg aatatataat aatataattt
     4021 taataagttg tttataatat ataaattata ttaatagtaa taatttatat attatgagaa
     4081 atttttgtat atatagagca ctctaaagat gaactatgta aaacaaggtt tatatattct
     4141 aattgtgtag aaaattttat tggaaatgaa tgcatattat tagaaaaata gtttagagat
     4201 atccaataaa cataaaaaat aatatagggg ataagggtgt tttatgaaga gatttttgag
     4261 gagaattatc ttagttttat ttattttatt gatttttata agtttcattt ctattaaatt
     4321 aattcataat gttggagatt atgggaaact gattaattat gttggtattg ttcgtggagc
     4381 tagccaacgc ctaactaaac tagagatgaa tcataaacca aatgatgaat taatagaata
     4441 tattgatgaa attttacagg aactgattac aggtcatgga aattatggct tagtactcac
     4501 tgattgtaat aagtataatg aggacttgct tttattggaa aaaaagtggg aagatttaaa
     4561 tagtgaaatt aaaaaagtaa gaatgaaaga accaaataac cagttattaa gtataagtga
     4621 agagtttttt tctcttgcaa atgatacagt gtttgaaata gaaaactttt ctaaagaaaa
     4681 aagtaattac ttaatgactt taataataat tatatctatt ataggcatat tagcatgtat
     4741 catattgatt ttacagtata gtaaaaaaat gattaaatta gaaaaattaa atgtagattt
     4801 aaaaaatatt gcatataaag atgaactaac aggagtaaat actatagaaa aatttaaatt
     4861 ggatgcaaat caaaatattt gtatgcataa ggataagaaa tttgctgtgt tctatattga
     4921 ttttgaaaac tttaaataca ttaatgatat atttggatat gattatggtg acatgatact
     4981 gaaaagatat gctaatctta tgatgaatga tataggaaaa tatgaaatat ttgcaagaga
     5041 aatagcagat agatttgttg cattaagatg ctatatagat aaggaagatt tagtagtaag
     5101 acaacgaatt gtagatagtg aactgattaa tacaacaaat gagattaaaa ataaacatag
     5161 cattactgtt gttagtggaa tttgctgtat tgaagatgta aatgaaaaat taagtataga
     5221 tggcttaata aatagagcga actttgcaca aaaaactgtt aagaataaac caggtactaa
     5281 ttatgctttt tataatgata gtattcgtaa aaaaatgatt gaagaaaata ctatcaagag
     5341 tagaatacat gaagctattg aaaaaagaga atttatagtt tatttacagc ctaaagtcaa
     5401 tttacataat caaaaaataa attgtgcaga agccttagtt cgttggttga ctccagacaa
     5461 aggtattata tctccagcaa tatttattcc agtattagaa aagaattttt ttattgcttt
     5521 agtagataaa tatgtttttg aggaagtttg caaatggatt agaaagagat tagatgaaaa
     5581 taaacctttt gttcagatat cagttaatgt ttccagaata caattttata atactaagtt
     5641 cgtagaaact tattccaata tacaaaataa atacaggata cctaaaaata ctatagaaat
     5701 tgaatttaca gagagtgttg cttttgagaa tcaaaatcat cttttggaaa ttatacatga
     5761 cttgcacgaa aatggattta cttgttcttt agatgatttt ggaaaaggtt attcgtcttt
     5821 aagtgtttta aaagatttgc catttgatgc tttaaagctt gactctatgt ttttcaaggc
     5881 tagtttagat aaagataaag aaaaaatagt aataaaaaat attgtacata tgttaaagga
     5941 gcttaatatc acaactgttg ctgagggtat tgaatatgag gaacaagttg aatttcttag
     6001 ggatattggg tgtgatttag ttcagggatt tgtattttat aaaccaatgc cgatattaga
     6061 gtttgaagaa atattggata aagagtttgt ttataatagc taaaatgtac tttgtaaaat
     6121 acaaactaat taagtaaaat tattctacac tgaacaaatt ttcattttat ttaccatata
     6181 agaatgcgta atgatataag tatttgaaaa gccaccatta tatgaaaatt aaaaagaaaa
     6241 taaataattt ttcgataaaa aagagactat gagaaaagtc acccatagtc tcctaaatat
     6301 agttattttc ttcctgcaac ccattttaag ccccaatgaa attcagtatc catttctcta
     6361 tgacctttga agtatttaac tactttttca acactaaatg tctcatcatt tacattttct
     6421 atcaatgcta ttgaacacat attatagcca tttttatgtt catcaagttt gacaactaag
     6481 tctgaatctt gtttttgttt gattgttaca attccatcag cttcagacca gttagccaca
     6541 ccttcatata taaaagcata aataagtatt ctttttatct cttttatttt attaccattt
     6601 attcttaaat tttctccttg tgcattactt cctgttcggt catctccatc taattgagca
     6661 aaaggtggat tgtctaaact accaaaagca tttcctaatg cttgaacagc accttttaca
     6721 ccatttttca tctcaaatag gcaacccaaa tctaaatcta tattactgct tcttaaagag
     6781 ccaaaaaaac cctttttttg tactttttga ttccaattta aattaactaa gatttcacct
     6841 aaatcgctat tttccttttt tgtaaggttt attttttgtc ccttttttaa ttctatagcc
     6901 atagtaatct tcctccacaa acatagattt atttaaatgg tagcacttaa taagtcaata
     6961 ttcaacaaga ttagaataat aatattaaaa ttatactaaa tatactaaaa agtaggaatt
     7021 acaatacctt tgtatttttc ttcaattaag cttcttgctt tatctgatgt aagaacatct
     7081 tgtagaactt taatcttttc actatcttta tcttcagttc taaatgctaa aagatttgca
     7141 tactcatcat ttataggagc tgtataaatt ccgtttttct tggcatcaag accagcaggt
     7201 acagcataag tagtatctat aaatgcagca gttacatctg gaagagaaga tggaatttga
     7261 gcaatatcta actctttgaa ttgtattccc tttggatttt ctattatgtc cttagggcta
     7321 actaatccat cacctttagg caatgttaaa agtccaatac tttcaaggta tctaaggttc
     7381 ttagaacaag aagaaggatt attgcttatt gcaattgtat cacctttttt aaattcatca
     7441 acagatttta tcttataaga gtaaagtatt gctgggcata catatagttt tttaccagcc
     7501 attattttgt aacctttggc cttaacagct tcttttagat aaggttcatg ttgaaataga
     7561 tttgcatcaa tctcaccatt atttaaagct tcgtttggaa gtatgtaatc atcaaagttt
     7621 ttaacctcta aagtatatcc tttttcctta ataagtggtt ttaattcttc taataactct
     7681 ccacctggaa ctaaagtagc accaacaaca atttttttat catctttagc tttagaacat
     7741 ccaaccacag ctaaagttaa tactagacat aataataaac ataataattt tttgaatttc
     7801 atataaattc cctcctgaat ataattgatt agttaaaaat aaaatactat tctttatcag
     7861 actgcaaaat aaaaataagc ctgagtttaa actcaggctt taaaagctaa tttagactca
     7921 tctttcagta taatactgca ggatttagca ccaatgtata taaaaatata ctggttgctg
     7981 ggtttcatag ggccagtccc ttcaccactc tggataagaa gtatcaattt ttaattatgt
     8041 tataaatatt atcatgattt tttacgtctg taaatataat tttataaata ttttaaaatc
     8101 tttagtgtat tttatttaac acctaaaatt ccagaaacta gaatatcagt atcagcacct
     8161 aagaaatagt cgtttatttc aatagaattt agggtgtttc tcaaagcatt ttcttcatgt
     8221 cttatgccaa taagtttatt ttctacaaat gaaacatcac attttccaaa aaaatctcca
     8281 aaaaatttta tgctagttat tatgccttta tcaacattta aattaaactc aacatttcca
     8341 ccagaatatt ttaattcatt tgaaagagta tattttggtg aattaccaaa attccaatcc
     8401 caagtttcat attttgattt agtaagcttt tctatttgtt ctatatcaag ttcactcaaa
     8461 caataattag tattatcagt gtttgtttta gaaagatagt tcattatagc atctttaaat
     8521 tctaatatgt ccattttaga gtgtaaatgt tcacttatat tggttacacg agattttaca
     8581 gattttattc cttttccttc aaattttata ggtttaactt ttaatgcttt tgagaggtca
     8641 tttatttcag atgaaaataa aagtgtacca tgatgcatta ctttgttttt gtagttgtac
     8701 tgagcatttc cagaaaattt cttgccgtct ataagaaggt catttcttcc agaaaattca
     8761 gcattgacat ctaatgtttt aagtaagtct attattggtt gagtgaatct tctgaaatca
     8821 ctaaaattat tattgttaca agctataaat gtaaaattta tatttcctaa atcatgaaat
     8881 acagccccac caccagactg tctcctaacg acaggtatag aatattcttt tatatattct
     8941 aaatttattt cagaaagtgt gttttggttt tttccaacaa ttatagaagg ttcattcctc
     9001 cataaaatga ataggtcttc atcaaaattt tttagaagat attcttccat tgctaaatta
     9061 aaataagggt ttgttttttc attataaatt aataacatta aagtagttcc tccatataat
     9121 tgataaaatt tttattatga gtacaattaa ttttataatt cgacaataat gtaaaaactc
     9181 ctttaaatta gaaattttaa aaactacctt gcaaagttta aataaataat atatactcaa
     9241 aatatgttta ataaaagtga atagaagggt agaggcgcaa taatctatca gtactaataa
     9301 ggagttaagc acatagagtt attaggaaag gagatattgc cgaagtttta taatcgatgc
     9361 tttaagatta tattgctggg ggtacataga aaatatgtac aactgtcaca ggtttatttg
     9421 tggtgagcta tcatttaagg aattatatta tatttatttt tactattgtt gatatattgt
     9481 aatgtttaag ccttgagtgt ttaccactca aggctttttt agttttattg taacataata
     9541 ccctatacag ttcacaaaat taaaaggaga gggagattta tatgaggaac aaaaaaatta
     9601 atattatttt tctgacgaca atcatgttca taatgtcaac agtaatggtt tttgcagaag
     9661 aggatataga cactattgca ctagctaatg cagaaaaatt tggaatttta actttaatac
     9721 caccattagt tgctataata cttgcattta taactaaaaa cgtaataatt tctttactta
     9781 taggtattct ttctggtagt tttataatta aagctagtgg tattaatgtt tttgcgacat
     9841 ttatacaagc atttttagat ttagtagaca gagctttagt atctttagca gacccttgga
     9901 atgcaggaat aatactacag gttttggcaa ttggaggagt aataaatctt gttgctaaaa
     9961 tgggaggagc taaagctata gctgaagcac ttgctaaaag agcaaagtca gcaaaaggga
    10021 cacagcttat aacatggttt ttggggcttt tagtattctt tgatgattat gccaattcat
    10081 taatagtagg tcctatgatg agacctgttg cagataagat gaaaatatca agagaaaaac
    10141 tagcctttat aatagatgct acagcagcac cagtagctgg tttagctata atatctacat
    10201 ggataggtct tgaggttggt ttaatacatg atgcttttga aagtataagt atagatgtag
    10261 atgcatttgg tatattttta aatacaatac catttagatt ttacaatata ttaatattag
    10321 cattcattat aatatcagcc ttattattaa aagaatttgg accaatgaga aaagctgaaa
    10381 taaaatctag aagtagaaaa attgatatag accttgatga aggcgtagaa gagttggatg
    10441 atttggctcc aaaaaatgga gtgaaattga gtgtatggaa tgctataatc ccaataggaa
    10501 ctttgataat agttgcatta gcatcatttt attatagtgg atacacatct ataatgggag
    10561 gagaggataa ggctctgata caactattta caaattctcc atattctttt gaagcaataa
    10621 aagaagcatt tagtgcatct gatgcatcta gagcattatt ccagtctgca cttgttgcaa
    10681 gtttagttgc tattataatg gctgtaataa aaaagatttt tacaatatca gaagcaattg
    10741 atgtttggat agatggaatg aaaagtttag taatcactgg tgtaatatta atacttgcat
    10801 ggtcattaag ttcagtaata aaagagttag gtacagctaa atttttaata catttattgt
    10861 caggttcact accaccattc ttattaccaa gtttaatatt tggtttagga gcaataatat
    10921 cttttgctac tggaacagct tatggaacaa tgggtatact tatgccactt gcaataccat
    10981 tagcatactc attaaatcct gatatgtctt atgtaatagt aagtactagt gcagttttaa
    11041 caggtgcaat atttggagac cattgttctc caatttcaga tacaacaata ctttcttcaa
    11101 tgggagctgg gtgtaatcat atagaccatg tcaacactca aatgccatat gctatattta
    11161 cagcagtaat tactattgta tttgggtata taccagctgg acttggattg ccaatatata
    11221 tagtattacc agttgcaata gctgctatat ttgtaggtat tcaaataatt ggtaagagag
    11281 tagacgaagc ggaaatagaa cttgtagaat aaagatataa ataagtttca ccttttatta
    11341 tcattatttt gttagttttt agataatttt aaaaagttat tgaaaataat agcgaaatat
    11401 agtaaaataa aagagtgata agcggatgtg gcggaattgg cagacgcact agacttagga
    11461 tctagcgcca ttggcgtggg ggttcgactc ccttcatccg cactttacag tacttaattg
    11521 tgctgaaaaa aactggggtt gctggctttc ggagtgggct atcccgtttt tattttttgg
    11581 tatatatgaa agattggcac tttaatatga agtgcttttt ttataggcaa aaaacagtac
    11641 atttatttct gttttattgt cattaattta ttagaacatg ctttagttaa gaatatgtta
    11701 ataagcaatg ttcacattct tgataaaata tggaatatat gtatctttac taaggcagaa
    11761 atgaaataac taaactacta aatgatatta taagatgata aataagtttc agtttattgg
    11821 atggttgaag taatcagaaa ttggaatttt atagtcttaa tataatgtat gaaattttat
    11881 agcaatgtat ttcataagta taaagtgact aaaattttaa aaaatataca aattctatag
    11941 aagctaaata atttcaactc tattttaaaa atcttatttt tcacaagttt aaaattgtaa
    12001 acgatttcat caagtctatg aatatacttt taacatgtta tagtaaatct caatataaat
    12061 ttacatttgc ttccttgtat gttattttaa taataaatta agtgaaaatg ttattttaca
    12121 ttaatatata atatttttgc ataagaatga ataatataaa agcgaaataa ttgataataa
    12181 aaacttaaca aaaaaattaa tacataaaaa aaaataaata taatgtgttg acatttaatt
    12241 gaaatattca tacaataaaa ttgaaaataa atatttccaa atgagattag cgagagagtc
    12301 ctttatacga aaaggcgccg aagaagaaat ttaagaaatg ccaattttta gagaagcttt
    12361 caggcaaaaa tatcgctaat tgatgggact ctggagagac ttaagttaag atactataag
    12421 tcaccgaaga agcaaaataa tattaaatta ttaaatcttt caggtataca aacagggata
    12481 tataggctag gattattttc catgctgata tatctttttt ttatgaaaaa gtacaggaaa
    12541 taatatcaaa gttacttaaa tacagtaggt ctaattttat agggagggtt atatatgaat
    12601 gaattgaaaa gagtatcttt gtataacata cacaaagagc ttggagcaaa acttgttgaa
    12661 tttgctggct gggaaatgcc tttagaatat gaaggtataa ataaagagca tgatatggtc
    12721 agaaaaagtg caggtatatt tgatgtatct catatgggag aggtacagat aaagggagta
    12781 gagtcagaaa aatttataca aaacctagtt acaaatgata taagcacatt aaatataaat
    12841 gacattatat atacacctat gtgttatgaa aatggtggag tagttgatga tttattaata
    12901 tataaatttg gtgaagaaga ttatttattg gtaataaatg caggcaatat agataaagat
    12961 gtagcatgga taataaaaca aagtgaaaga tacaatgtag atataaaaaa tatatctagt
    13021 gaagtgagtc aattagcaat tcaaggacct aaagcagaag aaatccttca aaaaatcaca
    13081 gatatagact taaactcaat aaaattttat aagtcaattc catcagtaaa agtatgtggt
    13141 tgtccttgtt tagtttcaag aacaggatat actggggaag atgggtttga gatatactgt
    13201 gaaaataaat atgcagaaat aatttggaat gaagttctaa aggttggagg agaagatata
    13261 tgtccagctg gactaggttg tagggacact ttgagatttg aagcagctct acctctatat
    13321 ggacatgaaa taaatgaaca tatatctccg gttgaaggtg gtttatctat ctttgtgaaa
    13381 acaaataaag aatcatttat tggcaaatca attttatcaa aagaaaaaga aaatggagcc
    13441 aaaagaaagt tagtaggatt tgaaatgcaa ggtaaaggaa tgcctagaaa tggatatgat
    13501 ataaggattg gtgataaaat agttggattt gtaacaacag gatgtgcatc tccaacaaca
    13561 ggaaaaattt taggtatggg aattatagat tctgagtatg caaaagtagg aaatgaaata
    13621 ggtatagcaa tcaggaaaaa agttgttcct gctgtgatag ctaagaaacc tttttataaa
    13681 aaacaatata aaaaagataa tattatatta aacaaagaaa ataaattttc atatatacct
    13741 gctacaagtg aagataaatc aaaaatgtta aaagtagttg gattaaattc agttgatgaa
    13801 ttattttcag atataccaga agaagtaaaa ttaaaaagag atttaaattt ggaaattgga
    13861 aaatctgaat tagaggtaag taaaatagta aaaagattgt cagaagaaaa tctaagctta
    13921 gaagacctga cttgttttct tggtgctggt gcatatgacc attatatacc atcaattata
    13981 aaacatataa cgtcaagatc tgaattttat acagcataca ctccatacca agctgaaata
    14041 agtcaaggaa ctttacaagt agtttttgaa tttcaatcta tgattgcaga aattacaggt
    14101 atggaaattg caaatgcatc aatgtatgat ggagcaactt ctgcaataga agcatgtata
    14161 atggcaatga atcagactag aaaaaataaa atagtggtgt caaaaactac tcatcctgaa
    14221 actttgtcag tattaagaac ttatttacaa tataaagatt gtgagatagt agaaattgat
    14281 ttttgtaatg aatatgggac tacagatata gaaaaattaa aagcttctgt agataaagac
    14341 acagcatgtg ttcttataca gactcctaat ttctttggaa ttattgaaga aatggaagaa
    14401 atagaaaaga taactcatga aaacaaggct atgttaatta tgagtgtaga cccaatatca
    14461 ttaggagttt taaaaacacc aggtgagata ggtgcagata ttgttgttgg agaagcccaa
    14521 tcacttggaa atcctcttaa ttttggaggt ccttatgtag gatttttagc tagcaaatct
    14581 aaatatacga gaaaaatgcc aggaagaata gttgggcaaa gtttagatac agaaggtaag
    14641 attgcatatg tattaacttt acaaactaga gaacagcatg taagaagaga aaaagcaact
    14701 tctaatatat gttcaaatca agctttaaat gctcttgtgg cttcaatata tatggctact
    14761 atgggtaaag aaggatttaa agaggttggt atgcagtcta tgaaaaaagc acattatact
    14821 tataataagc ttgtacaaac tggaaaatat aagccaatat ttaaaggcaa gtttttcaaa
    14881 gaatttgcta tacaaggaaa tctcaatata gaaactataa atgataaact cctagaagaa
    14941 aatatattag gtggttataa tttagaatac aattatccag aattaaaaaa ttcaacttta
    15001 ctttgtgtga ctgagaaaag aagcaaagag gaaatagata agttagttgg aataatggag
    15061 gggttataat gaaagaatat aatagtttat tgatagatat atctaaaaaa ggtagaaaag
    15121 catactcact tccaaaacta gatatagatg atataaaaat agaagatatg attgaccaaa
    15181 atatgataag aaaaagtgaa ttgaatttgc cagaagtcgg tgaattagaa ttagttagac
    15241 attatacatt attatcaaat aaaaactttg gtgttgatac aggtttttat cctttgggtt
    15301 cttgtactat gaaatataat cctaaaataa atgaagatat ggcagcactt ccaaacttta
    15361 ctggaatgca tccatatcaa tcttcagata cagctcaagg ttctctttcc ttgatgtatg
    15421 atttatcaag aagactttca gaaattacag gtatggatga agttacacta caaccttcag
    15481 caggttcaca tggtgagttt acagggctta tgattataaa agcatatcat gaaaatagag
    15541 gtgaccataa gagaaccaaa gtgataattc cagattctgc acatggaaca aacccagcaa
    15601 gtgcagctat ggcaaacttt gatgtgattc aaatagcatc tgataaaaat ggagctgtag
    15661 acataaatgc attaaaagaa gttttaaatg atgaagtagc agctcttatg cttactaatc
    15721 caagtactct tggtttgttt gaaaaaaata taaaagaaat agctactctt gtacatgaag
    15781 caggagggct tttgtactat gatggtgcaa acatgaatgc tattatgggt ataacaagac
    15841 ctggaaacat ggggtttgat gtggttcatc ttaatcttca taagactttt tctactcctc
    15901 atggaggtgg gggaccagga gctggtcctg ttggagttaa aaaagagttg gtatcctttt
    15961 taccaatacc agtaattgaa aaaagagaag ataagtatat attaaattat gatagagaaa
    16021 agtctattgg aaaaattaaa aacttttatg gtaattttgg agtgcttgta agagcttaca
    16081 cttatatatt aactatggga agagatgggc ttaaagaagc tagtgaaatg gcagttttaa
    16141 atgctaatta tataaaggaa agtataaaag atgattatat tttgccaata gatactttat
    16201 gtaagcatga gtttgtatta ggtggattac caagaggaga ggcaaatata aaaactattg
    16261 atattgcaaa aagactacta gattatggat accatcctcc aacaatgtac tttcctctta
    16321 ttataaatga ggcacttatg atagagccca cagaaagtga gagtatagag acattagata
    16381 gctttataga cgctatgaaa agtgttgcta aagaagcaaa ggaagaacca gaactattga
    16441 aaactgctcc acataatact ttagtaaaaa gggtagatga tgcaagggca gtaaaaaaac
    16501 ctatactgac atggtcacaa agataaataa ttaaaaaata gagatttaaa gcataaataa
    16561 atttgaattt gcaaaaaaag ctatctaact taatctagtt taggtagttt ttttgtattg
    16621 gtagatataa gattttctat taaaaattta aattatatta ttactcatat aaaatattaa
    16681 tgtaat
//
LOCUS       DAMKOJ010000075        16058 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000075 DAMKOJ010000000
VERSION     DAMKOJ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16058
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.081"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            585..2015
                     /locus_tag="PC592_002779"
     CDS             585..2015
                     /locus_tag="PC592_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4056727.1"
                     /translation="MSSQESKPKGNFISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAIAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIGDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            2118..3221
                     /locus_tag="PC592_002780"
     CDS             2118..3221
                     /locus_tag="PC592_002780"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF4056728.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAMEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKEEPSIG"
     gene            3236..3472
                     /locus_tag="PC592_002781"
     CDS             3236..3472
                     /locus_tag="PC592_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4056729.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            3489..4538
                     /gene="vorB"
                     /locus_tag="PC592_002782"
     CDS             3489..4538
                     /gene="vorB"
                     /locus_tag="PC592_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF4056730.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREEDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RISENEQQWEDYQIEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4540..5280
                     /locus_tag="PC592_002783"
     CDS             4540..5280
                     /locus_tag="PC592_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF4056731.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSANGRDISTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWSV
                     SLEKSIKWMEEEIVPYYTLGEFKQRDGE"
     gene            5283..5822
                     /locus_tag="PC592_002784"
     CDS             5283..5822
                     /locus_tag="PC592_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF4056732.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENIA
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNIQNEAAFMEGYNNAI"
     gene            5946..8045
                     /locus_tag="PC592_002785"
     CDS             5946..8045
                     /locus_tag="PC592_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HDF4056733.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKDTDRVYYVN
                     PKREELFGRKCYKTIQEVPEIVDCVVVCTPRNVVPSVLKDSAELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDNYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPTNSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDSSVGFTMVGANIRDEE
                     NEMHETLCQAVSEAREQGLKKPVFAVPTLEGNRYLDYRNRLEYNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8312..8827)
                     /locus_tag="PC592_002786"
     CDS             complement(8312..8827)
                     /locus_tag="PC592_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HDF4056734.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YSAPTNPPVTI"
     gene            complement(8919..10130)
                     /locus_tag="PC592_002787"
     CDS             complement(8919..10130)
                     /locus_tag="PC592_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF4056735.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIKEIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVAFIKELSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTVSASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            10788..12230
                     /locus_tag="PC592_002788"
     CDS             10788..12230
                     /locus_tag="PC592_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4056736.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGSI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPSETKQRLKNVKKIY
                     IIGKELSISKSVENELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSVAQNNGDSSTKGDSPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            12272..12625
                     /locus_tag="PC592_002789"
     CDS             12272..12625
                     /locus_tag="PC592_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056737.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFVTDIFNLADVQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTSWILSLIVSLLTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HIAAKFYYKIKTFKN"
     gene            12815..13636
                     /locus_tag="PC592_002790"
     CDS             12815..13636
                     /locus_tag="PC592_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF4056738.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNIPVPSKAYFKGLSKEDAYYKYFNSILETNREFRDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDIIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFINIEKVKSNNIA"
     gene            13894..15777
                     /locus_tag="PC592_002791"
     CDS             13894..15777
                     /locus_tag="PC592_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDF4056739.1"
                     /translation="MSNKNKDNITLSNQIKRTTQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIIMNKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQKEKILFTEKRIIELGNENDEKELCEISNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDSSINPEGTDEWGATPTRENFTGGDLQGV
                     IEHLDYLSDLGISGLYFCPITIGKTNHRYDTIDYMEIDPALGDKRTLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKDWFYIKDMNKIDIPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIEYLLDVGKYWIHEFDIDAWRLDVSNEVDHAFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVNEVIFNLLGSHDTTRILTYANGNVDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNRDIFNFMKKIIRLRKENKELRSISNEWVLADKE
                     NGAIILKKESIFIIINNSSKDIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
BASE COUNT         6236 a         1803 c         2866 g         5153 t
ORIGIN      
        1 gtacgatatt tgttttattg gctttagatt aatatagcta taataattta tgatattaga
       61 tagaaattac ataaaaatag aaaattgaaa attctgaaat ttttgcatat tgatatttat
      121 cgcgtagatt ctttttttgt aattgtaaca tgcttttatt tttaaatcaa tagtacatgt
      181 ataaaaataa aaggaattta aataagaaaa agatattttt aatatctgga tgtagtataa
      241 aaatatcttg aataaattac tcttgaataa aattgaaaaa attaaaatca actagaaata
      301 cgataaaata atttaaaata tgtattttga tgacatttaa aaacaataaa ataataaaaa
      361 acaaatctaa attaagctta aatggctttt tagttaattt taatagtaaa aattaaactt
      421 aaaaaatatt tgacaattat gaattttgag aatataattg aattaaaatt agacacatat
      481 aaaaatatac tctgaatcaa gaaggatata tttaagattc aaaatatata ttattatacg
      541 tgaataataa aaaagtaagc aaattttata agggaggggt agatgtgagt agtcaagaaa
      601 gcaaaccaaa aggaaacttt atatcaaatt ttagagatga tatgagagac cctaagaaaa
      661 gagcaatata cacatattca agttctataa acctagcgta caattttata ggttactttg
      721 tatcaactgt tacaaatatc tttttaaccg atgtggcaaa acttggtgta attatggcag
      781 gtggtatgca aatcatacaa tctttcataa aaattgctat agctcctata acaggtacag
      841 tatttgacaa acaaccattc aaaaaaggaa aatattatcc atggcttaga tatgcaccag
      901 cagcactagc attaacgtat ggaatatttt tcatagttcc attaatgaaa ataagtccag
      961 cattactttt acctttgatg acagctttat tattaatagc atcttgtgct cagcaagtag
     1021 ttttcactat aatttatgct atttaccctg tagttgctaa gacacctaga gacagagtta
     1081 taggttcaac tactacgaat atattcaaag aagttggtaa attcttagta ggtttttcat
     1141 atccgttatt attagtttta tttgcagatg tattaggtgg agagggaatg ggttatttag
     1201 gtacctattt attctttgca gcaggatgtc ttttagtatt ttggttttct tcaacagaga
     1261 taataaaatc tggagcagaa gaagaagttc ttcaaaaaga agagaagcca aagattaaag
     1321 caagtgaaat ggcaaaagct ttattcacta atgtaccact tatgatggca ttttgtctag
     1381 aatttcttat atgtataaga tctataggat taggaccttt ggctccatat tattttaaat
     1441 atgtaatagg ggatgaacgt ggattagcag tatttttatc aatcatgcct ttggtaagtg
     1501 tagcgttcat gttttttgca ccagtattca taaaaatctg tagagagcaa aaactagctt
     1561 cgataatttc tttttctata tgtgcattat gccacttatt ggttgcatgg actccttggg
     1621 ggaaaactac tttaggagta actatgttgc tggcaattgg tggaggtttt tcaaatgtag
     1681 tatcaataat aaatcttaat ttttttgcag gttcttgtga ttatggtcac tggaaatcag
     1741 gaaaagactt acctggttta agtatgtcat tatatccagt tgcaatacaa gtaggagtat
     1801 tacttgcaac tactataaga acagttttaa tgaactcaat gggatatcaa gctgatatgg
     1861 tagtcacaga agcagttaaa tcaggtttta taaatatgat ttcttattct atggcaatac
     1921 ctttaataat agctgttgtt atagcaatac tatatccagt aagtgacaag aaattaaatc
     1981 aaataagaga agaactaaat caaagaaatg cttagttaaa agaaagttaa gtagatgact
     2041 aatttaagtt attaaagtaa gtagacgcaa tagcgtttat ataaatgaaa atacatatac
     2101 agagggggct tttaaaaatg atagaaaaat tattgagaaa tacagtaaaa gaattacatc
     2161 aatatgttcc aggtgagcca atagaaaaag ttaaggaaaa gtatggtgta aaagaaataa
     2221 taaaattagc ttcaaatgaa aatcctctag gtccatcacc aaaagcaatg gaagctatga
     2281 ttgaaatgtt aaaacaaggt caactttatc cagaaccaga agctaacgaa cttagaagaa
     2341 aattagctga aaagctagac ttaaaaccag aaaattttat tgttgctaat ggtgctgata
     2401 acgttatcac actaataggt gaggctttta taaatagagg agatgaagtt atatattgta
     2461 acccaacatt tccatcatat agaactgcaa ctataaaaaa tgaagggata ccagtagaag
     2521 tacctctaac agaagattat aagtatgatt tacaaggtat attggataaa attacagata
     2581 aaacaaaatt aatatgtgta tgcaacccta ataatccaac aggaacaatt gtagatgata
     2641 aagagttaga agaattttta aagaaagttc ctgaaaatat tataactata ttggatgaag
     2701 catatataga atttttaaca gttcctaatt atgtggatgg acttaagtat gtaagggaaa
     2761 attacaatgt tatagtaaca agaactttct ctaaaatata tggtcttgca gggcttagag
     2821 taggatatgg tattgctaaa gatgagataa taagaactct atttacagta aaagagcctt
     2881 tctctgcaaa ccgtgttgct ataagtggag caacagcagc acttgatgat gaagagttta
     2941 taaaagaaac ctatgaatta aatagagttg gtatggctta ctttaaagaa gagtttacaa
     3001 aaatgggatt tgatgttgta gattcacaat caaatttcct ttatgtagat atgaaaacag
     3061 atatacctaa gttatttgaa gacttgaaaa aaagagggtt tgtaataaga ccaagtgcta
     3121 cacatgcacg tgtaagtatt ggaactatgg aagaaaataa gaaatttgta gcagttttaa
     3181 aggaaatatt aaatattaaa gaggagccaa gtattggata atagatagaa atattatgaa
     3241 acggggtgta gatatgaact taaaaataaa cgcagagaga tgtaaaagtt gtgaatactg
     3301 cgttatatct tgtaaaaaag gagcattaaa aatatcaagt aagataaata aagaaggtta
     3361 tgctcatgta gaagttgatg agagtaaatg catactttgt ggaatttgct atcaagtgtg
     3421 tccagataat gtttttgaaa taattaaaga agaagcatgt caagaggctt agaaggagtt
     3481 gggataatat gaaaaaaatg tggaagggga accacgccat tgcagaagca gccctaagag
     3541 gtggttgtga attttatgca ggatatccaa ttacaccgca aacagaggta atggaatttt
     3601 tatcacatag aatgtctgaa cttggaagaa cttttataca atctgaaaat gagatggctg
     3661 ctatatatat ggtatatgga gcatatgcaa gtggaatgag gtctatgacg agttcttcag
     3721 gaccaggaat atctttaaaa caagaaggga tttcttactt atgtgcaaat cattaccctt
     3781 gtgtaatcgt aaatgtacag agatggggac ctggtcttgg ttcattggat tcagcacaga
     3841 cagactacct aagagatact agagggggag gaaatggaga ttatcatttg atagtttatg
     3901 caccaaacag tattcaagag actgtagatt tgatgtataa ctcatttgat gtagcggaaa
     3961 aatacagagt acctgttgaa attttgacgg aagcagcttt aggtcaaatg atggaaccag
     4021 tagaatttcc agagtttaag aagagagaag aagatttagg ttggacttac gatggaagta
     4081 atagagacca tgcaaaggtt gcagataacc aaaagccaac tttttgtatg gagaaacgta
     4141 tgagaataag tgaaaatgaa caacaatggg aagattatca aatagaagat gcagaatatg
     4201 tgtttgtagc gttcggtata ccatcaagaa caactatgaa tgctgttaga agacttagag
     4261 aacaaggtga aaaagttgga ataataagac caataacagt ttggcctttc ccatataaag
     4321 catttgaaaa ggtaagcaaa gatgtaaaag gatttatatc agtagaatca acagacacag
     4381 gtcaattagt agaagatgtt gctttagcat caaagaaagt atgcaaagaa aatgtacctg
     4441 tgtatggtct atttagtgga aatcatatac caaaaacatt gcaagtaatg gacacttata
     4501 gcaaaataaa atctggcgaa atcaaggagg tgttctaata tggctacaga aaaattaaca
     4561 cctagcgttg tttcaatacc aaacaagttt tgcccaggtt gtggtcatgg aatagtaaac
     4621 cgtataatag cagaggtaat agaagagcat ggatatgaaa aaaatcatgt gttgacatta
     4681 ggagttggtt gtgtttgtaa tatgaatttt agctggaatg gtgataagat gcaaactgca
     4741 catggtagag cttcatctac agctatagga gttaaagtag cacttccaga tacactagtg
     4801 atgacttatc aaggagatgg agatgcttat gtcataggtc tttctgaaac tttaaataca
     4861 gcatatagaa atcataatgt gactgtattt gtaataaata ataataattt tgcaatgact
     4921 ggtggacaaa tgtcatggac cactatgcca ggtcaagtta caacaacaag tgcaaatgga
     4981 agagatataa gtactactgg tagtccacta aaagttcctg agatggtggc aaacttcttt
     5041 gatgtagcgt atgtagcaag aggctcagtt catagcccaa aagaaataat taatctaaaa
     5101 aaatatataa aaaatgcaat agaagctcaa ttaaatggag agggatattc cttagttgaa
     5161 atattagcgc cttgtccaac taactggagt gtatcactag agaaatctat caaatggatg
     5221 gaagaagaaa tagtgccata ttatactctt ggcgaattta agcaaaggga tggtgaatag
     5281 ttatggaaaa agagttagta tttgcagggt ttggtggtca aggagtttta actcttggtt
     5341 tgattgtagc tgagtcagca cttgaattgg gtaaacaagt aacttggatg cctgcatatg
     5401 gtccaactat gagaggtgga aaagcctata gtgtagtaaa gttttctgat gagagtatag
     5461 gtggacctga tatggaagaa atagatgttt tagtagcaat gaataaacca tctttagatt
     5521 atataaattt agtcaaggaa ggtggaacag tagttattaa tacatctgca atagatgaga
     5581 atatagcatt aagagaagat ataagtgtag ttaaaataaa ttgtcaagaa ttagctcaaa
     5641 aagtaaataa tccaaaagca gcaaatatag tagtacttgg agcattaatt gctaagactg
     5701 gattgtttga aaaagaatta gctttaaaaa ctatgtgtga tttctttgag gaaaaaggaa
     5761 aaggaaagtt taatattcaa aatgaagcag cattcatgga aggctataat aacgccattt
     5821 gataaattac ccttatctta agtgatttat ctcgagattt aataatcttt agtgccaaga
     5881 gaaatttcat cttgagataa aattcactta aaatcacaac tataaacata taggagcgtg
     5941 aatttatgag tttggaaaaa cttatcagac caaaaagtat tgctatagta ggagtgactg
     6001 ataaacttgg ttttgggaga agtgcagcac ttagtatagt aaaaagtaag gacacagata
     6061 gagtatatta tgttaatcct aaaagagaag aattgtttgg gagaaaatgt tataaaacga
     6121 tacaagaagt tccagagata gtagactgtg tagtagtatg tacacctaga aatgtagttc
     6181 catctgtatt aaaagattct gcagagttag gaacaaaggc agcagtagta tatgccagtg
     6241 gatttgcaga ggaaggtaca gaggaaggta cagatttaga aaatcaactt atagaaatat
     6301 caaatacata cgatatgaaa atattgggtc caaactgcat gggattgcta aattgtatag
     6361 ataaagttaa tttgtgggca ggaggttcta aatgggattt agatactaaa aagcctggta
     6421 taggaattgt agggcagagt ggatttataa ctgctgagat tgtttcaagt gattatttta
     6481 atatatctta tggtttttca acaggaaatg gaaacatagt tacactagaa gatgcagtag
     6541 atttccttgt agatgataat tatgcatcag taatagcaat ctaccttgaa ggtttaaaaa
     6601 atcctcaaaa atttatagat gctttaaaaa gagcagcaca aaaaagaaag ccagtgataa
     6661 tcttgaaatc aggaaggtca gaaaaaggag ctatttctgc tgcttctcat acaggaaatt
     6721 tagctggttc aagtaaggct tttgaaagta tttttgaaaa atatggagta atttctgtag
     6781 aaaatttaga acaatttatg tgcttagcac aagcttttag tgttctagat ggcaatttac
     6841 ctacaaattc taattttgca gcaataaact tctcaggagg agaaaatacg atttgtgcgg
     6901 atttagcaga agaaaatggt gtagaacttg cagagatatc ttctgaaact aaagaagaaa
     6961 tgaaaaaata tcttccggga tttgcaacac ctaaaaatcc actagatgct acaacagcat
     7021 tattccacga aaaggatatg atagtaggtc tattacatac ctttgaaaag gacagtagtg
     7081 ttggatttac tatggtaggt gcaaatatac gagatgaaga aaatgaaatg cacgaaacac
     7141 tatgtcaagc tgtaagtgaa gctagagaac aaggattgaa aaagcctgtg tttgcagttc
     7201 ctacacttga aggaaataga tatttagatt ataggaatag attagaatac aatcaagtgc
     7261 ctataatgtc atcagttgga actacattta cttgttttaa taaaatggct aagtttatag
     7321 attatgatta ttcaaaaagg actttagaat ttaaagctgt taagaaaaga gagtcaaata
     7381 atgtagtagc attatcagaa ttagatagta agattgagat gaagaaatat ggagtaccag
     7441 ttccaggaca aggtaatgca aaaagtattg atgaattaga tgaaatctta aaatatatta
     7501 aatatcctgt tgttttaaaa ataaattctt ccgaaatctt gcacaaatct gatgttggag
     7561 gagtcaaaat aggaattaag aatagagatg aggcagtaga tgcatataat gagattttaa
     7621 ctaatgtaaa aaaagcaaaa ccggatgcta atattgatgg tatattagtt caagaaatgg
     7681 tagaaagtgg tatagaaatt attattggta taactaatga tgaccaattt ggaccaatgt
     7741 tgctagttgg gttaggagga gtctttgtag aagtatttaa agatactaca ttatatccat
     7801 tacctataaa tcacgatgaa gctattatga tgcttaaaaa actaaaatca tttaagcttt
     7861 taaatggtta tagaggaagt gagccttgcg atattgatgc tcttgcagat atgatggtca
     7921 aattaggaaa atatgcttac gaaaataagg atgaagtcaa ggaaatagac ttaaatccag
     7981 tgtttgtata tcctaaagga aaaggcgtat gtgcagtaga tgccttaata gttaaatata
     8041 aatagtttat aagttttggt acttaaccat aattaaagca ctgactgaaa atcacatttt
     8101 gtaagttaaa tagtgtgatt ttcggtcacc ccaaatttac tttaaaaaaa ttttaaagta
     8161 aaagtatagt tttaagtttc attgtgaaat agtactgtaa aaacaataaa atactacata
     8221 taaaacgaat aataaaaggt gttttaatga taagaatcaa ttttgacttt cactaaaaca
     8281 ccttctttat tatatgaaaa atttttaaat gttatattgt cacaggtggg tttgttggag
     8341 ctgaatatgt acgattagca aattcttggt caacaaagaa tagaccacct tctccagcaa
     8401 gtttaacacg ttttatattg tcttcacaat ttgtttcttc ttctgcttgt tcagatataa
     8461 accaaagtaa gaattgagaa gttctaaagt ctgactcaga gtttgctaca gctgctaaat
     8521 tgtttattaa agctgtaacc tttttttcat gagctaacgt acgctcaaga atatccattg
     8581 cagaagtaaa gtctgaatct ggcattggga tagcatcaag ctgaaccttt cctcctacat
     8641 tgtgtaagta tttgtaaaaa aacatagcgt ggtctgtctc ttctttatat tgaacataaa
     8701 accaattaga aaatccttta agtccttctg cttcaaggta agaagacata gaaagataaa
     8761 gatatgcaga atataattca tggttaatct gctcattaag taatttttcc attttagctg
     8821 aaatcatttt tatacctcca aattttaaat gctcttataa aatataataa tattaaatgg
     8881 aaaaatattc aataaaagtg tttaaatatt ttacatattt aataaaaatt tatactacca
     8941 ttaaaaaagt tataacttac aatggctata gagccgatta atggtgcatt tgctccaaaa
     9001 tttgaatgtc ttacacttat ttttttatat ttagaaaaac ttgctgaaac agtcaatttt
     9061 tttaataatg tattttctat aaatgtacca ggaatattaa agtcatagcc tattattata
     9121 gaactacaat caatcaacgt aagtgtatta accaatgcat atgatacgta tgtacaaaat
     9181 tcatcaagca aaaacatagc gagactatct ttattatttg cctcatctat taatttgact
     9241 aaagaaaaat ctttacagtt aattaacggg gaattaggat aaatatggct caatgattca
     9301 attcttttaa ttagattact gacacttgta taataatcta aacatccatt gttaccacaa
     9361 ctgcacaatg gtccactaaa attaattgat gtatgtccta tctctccact ttgccctaga
     9421 ttgccagtat gaagtttatt ttctagaact agaccagctc caataccatt cattatgtgt
     9481 aggtatatat aatttgatat atttttacct aagccataca ttttttctgc caatgcgccc
     9541 gaattagcat cgtttattaa aaatattggc aaatcagaca gttcttttat aaaagctact
     9601 atatttaggt ttgatacatt tccaaagtct gggggattta gtatggtacc atttatatca
     9661 tctactggac ctattgaaga aataccaatt ccaattatat ctctcttgtt gattttcatt
     9721 attttggtaa acattctttt tattatatct tttaagacat catttgatag acatttaggg
     9781 taagtttcag aaagttgttt tacaatatta ccttttaaat ctgaaataat taccttacat
     9841 atatttcttc ttattaggat tccacaaata caaggtgata tattagaaat atctaataaa
     9901 ataggtttac gacctgatga atgtgcattt aaagttgatg actctatttc cttaatcatg
     9961 ttttcattaa taagttcagt tactagattt gataaagtca ttttagtaag tcctgtagac
    10021 ttagctaaat caaccctgga cataggtgta tttgtagaaa gtaatttcaa tattattaac
    10081 ttatttttaa tttttacatc ttttatgtta gaaccttgtt tgttactcat cttaaatctc
    10141 cttaaataaa gttaagtgtt ttatttattt tcaagtatgc tatcacctta taatagagca
    10201 acattttttt acttgaaaat atcattaatt agaatatatc acattatata tcataaaaca
    10261 caaaaaaatg ttaggcttaa attaaaaatt aaaagttaaa agttaaaagt agattgagat
    10321 ataaatagta gatactcaat taaaaaagat aatgataaca atatctgctt ttataaagaa
    10381 accaccattt caagcattac tttaagtagt taagttgatg gtagttcata tataataact
    10441 tgataaaagg tttacttaat aataaataga ttatgcaaat ctacaatcta tttattgtat
    10501 acaataaaat ttcattttgt aaaacagtga attaaatatg aaatacagag atagattttt
    10561 attacaaatt gttaccaaat atagatatat tagaacagaa atctagtaaa ttgtaactaa
    10621 aatgtaaatt tttcctttaa tctatacaat attatggaaa ctttttgtaa tctatgatat
    10681 aataacaaat atataattat taaattataa taaatgacta tagcgtagat gtattactat
    10741 gctatagtca tttttgaatt aaacttgata tatcaagggg gaagaatatg agaacaatta
    10801 gaagagtttt agcattaggc ttaacattag ctatatttct aataaatgta cctaatgtag
    10861 atgcattaac atcagataca attaaaggta ataatatata tgagacggct ggatcaatag
    10921 cagataaaaa gagttatgat acagcaatta tggtaaatat ggataattct atagcagatg
    10981 gtctttcagc aagtggtctt gcaggtgctg ttgatgctcc aattttgctt gcacaaaaaa
    11041 ataagatacc tagtgaaaca aaacaaagac taaaaaatgt taaaaaaata tacataatag
    11101 gtaaagaatt atcaataagt aaatcagtag aaaacgaact gaaaaataca ggagcacagg
    11161 taactagatt gggtggagat gacagaataa agactagtta tagtgttgct aaagaggtaa
    11221 atggtatcaa aaaagttgat gaagtgatac taactaatgc atataaagga gaagcagata
    11281 caataagtgc tgcacctgta tcagtaagag atatagctcc tatagtactt acagatggaa
    11341 agagtgtacc tttttcaaca agtaatgtaa aaacatatgc agtaggtgga agtatatcca
    11401 tgagcactag tttagttaat aaaactaatg ctaaaagact tggcggttca gatagatatg
    11461 atacaaataa gaaagttata aaagagtttt atccagatgc atcagaattt tatttaagtg
    11521 atggatatga tttagtaaat gcacttacag gttcaacaat tgctaaggaa aatccaattg
    11581 tattggtgtc agaaagtagt gataagtcta tattagcagg agcagataag attactagat
    11641 taggttcaat aagtgatagt gtgtataata agtgcgtttc tgttgcacaa aataatggag
    11701 attcgtctac aaaaggtgat tcacctatga aaaatgagac aagcatatta ggtcagccaa
    11761 cagctagttt agaagcttgt ttaaaatggg ccaaatctaa aaaagctaat gatttattta
    11821 tagagttaat accaatatta tatgatactg ctgttcagga aggtgtaaat cctgttttgg
    11881 cagtagctca atctgcaaaa gaaactggtt tttgtaattt tggtggagtg ttagatgcat
    11941 catttaagaa tccttgtgga cttaaaactt ctgtaggagg ttctgatact gataagaatg
    12001 ctcattcaag atttgatact tgggaagaag gaatattagc tcaaattcaa catttatgct
    12061 tatatgcagg acaagatggt tatccacttt caaatccagt agaccctaga catgaaaagt
    12121 ctttatttgg taaagctaag acagttgaaa gtctatctaa taattgggct ggaggtcaat
    12181 atggacaaga tttagtaaga atgatgggag aaattgaggc aacaaaataa ttgaagatta
    12241 tcaaatatcc aataaataag gattgattat tatgaaaaag agtaatattt ttagtattat
    12301 atttcctaca gtcataatgg tgctaatgtt tttaactttt gttacagata tatttaatct
    12361 tgcagatgtt caatctaaaa gtatttttgt tgtaggaatg gttttgattt ttccaatttc
    12421 ttttttaata caaggaataa tttgtgtatt aaataagact agttggattt tatctcttat
    12481 tgtgtcttta ttaacttata tagtattaat gtatatattt ttaaatgatt ctgcatatat
    12541 atatgtttta ctttatacag ctttttatat gattggacat atagcagcca agttctatta
    12601 caaaattaag acttttaaaa attaaattta agtatataaa attaatatta agggaagtat
    12661 ctttaatgat tttctaaaat caaaaatagg tgcttctctt tttgtaaaaa taaagatatg
    12721 taaataaaat ttaaccatta taattttctt ttaacaaatg tatacaataa acttgttgta
    12781 taattaagat agataaaata aagggaggga taatatgaat ttaatagata atcatattca
    12841 tactaatttt tcaagtgatg gaaaggattc aatggaagat acaataaaaa aagctataag
    12901 tattggtgtt agatatttaa cttttacaga ccatttagaa catgacgaag atagaggatt
    12961 ttgcataaat tataatgact atgttccagt gtttaacaag tttaaagaaa aatataaaaa
    13021 agacatagag ttattattag gtgttgaagt aggttataga aaacatctaa aaaatgaaat
    13081 agaagaaata ataaattcta atccttttga ttttgtattg tgctcaactc atacaattga
    13141 caatatacct gttccatcaa aggcatattt taaaggactt agcaaagaag atgcgtatta
    13201 taaatatttt aatagcatac ttgaaactaa tcgtgaattt agagattata atatatatgg
    13261 tcatttagat tatatatcta ggtatggaat atattcagat aatagagtta tatacaatga
    13321 ctttaaagat attattgatg aggttttaaa atcaataatc aataatggta gtggtataga
    13381 gctaaataca tctggttata gatacggact gaatgctata catccaaatg aagatattct
    13441 aaaaagatat aaagaacttg gagggtttat agttactgta ggttctgatt ctcatagagt
    13501 agaagatata tgcaaagatt ttgatgtggc ctatgatatg cttaagtatc ttgactttaa
    13561 atatgtatct ttatttaaag aaagagaaac ttattttata aatatagaaa aagttaaatc
    13621 taacaatata gcttagagtt tattttgaag taaattaatg gatagttaaa aagtcaatag
    13681 ttataatatt gtatcctcta gaaaaatact agaggttttt attttgcaaa aataactaaa
    13741 tagaattaaa tttaaacaat atagtttatt ttaaattgaa tagtttattg ttgatatatt
    13801 ttactattat atatttttat tgtgatataa tagtaaaata tattaaccta tctttagatt
    13861 atataaatta ttataaagga gggaaatttc aaaatgtcta ataaaaataa agataatata
    13921 actttaagta atcaaatcaa aagaacaact caaaatagtt taacaaaaga agctatatta
    13981 catataccaa tgagtaatta tgcctatggt tatgatagag aaacactaca tataagactt
    14041 agaactaaaa aaaatgaagc taaaagagta attttacgaa taggagacca atatgtttgg
    14101 gataaaggtg gtgcaggagg aggaaattta aatgcatctg gagttggttg gtctggtgga
    14161 acaaatataa taatgaacaa agaagtagaa actgaattat ttgattattg gatagctaag
    14221 tgtaaacctt taaataagcg ttcacgatat ggctttataa tagaaggcca aaaagaaaag
    14281 attttattta cagaaaaaag aataatagaa ttagggaatg aaaatgatga aaaagaatta
    14341 tgtgaaataa gtaatttttt tggatatcca tatttaaatt atatagatat acctaaagtg
    14401 ccaaattggg tgaaagatac tgtttggtat cagatatttc cagatagatt tgcaaatgga
    14461 gattcatcta taaatccaga aggaacagat gaatggggag ctactccaac tagagaaaat
    14521 tttacaggtg gagatttaca aggtgtgata gagcacttag attatttgag tgatttgggg
    14581 ataagtggac tttacttttg ccctattaca attggaaaaa ccaatcatag atacgataca
    14641 atagattata tggagataga ccctgcctta ggggataaaa ggactttaaa aaaactaata
    14701 gaagaagcac ataagagaaa tataaaaata atgttggatg ctgtttttaa tcatatagga
    14761 tattattcta aacagtggca agatgtagtt caaaataagg aaaattctcg atataaagac
    14821 tggttttata taaaagatat gaataaaatt gatattccaa tagaacagat agatgaaaaa
    14881 aatatacctt atgaaacctt tgggtgtgaa aaatatatgc ctaaacttaa tacagaaaat
    14941 tcagaagtaa tagaatattt attggatgta ggtaagtact ggatacatga atttgatata
    15001 gatgcatgga gattagatgt ttcaaatgaa gtagaccatg ctttttggag aaagttcaga
    15061 gaagaagtta aaaaagtaaa accagacatc tatatattgg gagaaatttg gcatggtagt
    15121 ttaccatggc taatgggtga ccaatttgat tcagttatga attacttgat gtcagaagcc
    15181 atgaaaaaat tcttttgtac agatgagata aatgctgaag agtttaagta tatgataaat
    15241 gatgtaatgg taagttatcc aatacaagtt aatgaagtta tttttaattt acttggaagt
    15301 catgatacta caagaatatt gacttatgct aatggaaatg ttgatagatt taaacttgca
    15361 tatatgttta tgtttgtaca aacgggatgt ccttgtatat actatggtga tgaaattgga
    15421 atggaaggag aattaagttc aatatctgaa ggacaaagaa aatgtatgga atggaatgaa
    15481 gaaaaatgga atagagatat atttaatttt atgaagaaga ttattaggct tcgtaaagaa
    15541 aataaagagc ttaggtctat atcaaatgaa tgggtgttag cagataagga aaatggagca
    15601 attatattaa aaaaagagtc catttttata ataataaata attcatctaa agatataatt
    15661 ttgacattac cagattattt agcaaataaa aaagtaaaag atttatatga agaagaaata
    15721 gttgatttaa aagaagaact aatgttagag aaatacaagt tcattatttt aaaataatac
    15781 aaaagggtat ttattttaga ttttatgtta aattattata cagtttaaac aaatctttaa
    15841 gaagataaaa aaatatggtc tataagggaa tgaattagaa gtagatttta aattaaagac
    15901 tagattagaa tagataattt tataaataat atcttaaata caagaaagaa aataaattga
    15961 ttattagtct aaaaaattct tgtagaaaga gggaataaga atgattgaag catttatatt
    16021 tgattaaaaa atagctacac acacttgtga ctttagtc
//
LOCUS       DAMKOJ010000076        16057 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.082, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000076 DAMKOJ010000000
VERSION     DAMKOJ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16057
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.082"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            90..971
                     /locus_tag="PC592_002792"
     CDS             90..971
                     /locus_tag="PC592_002792"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF4056740.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENDTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPEDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VAKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKHKLTNFGFKF"
     gene            1401..2402
                     /locus_tag="PC592_002793"
     CDS             1401..2402
                     /locus_tag="PC592_002793"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDF4056741.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            2519..3406
                     /locus_tag="PC592_002794"
     CDS             2519..3406
                     /locus_tag="PC592_002794"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF4056742.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            3474..4223
                     /locus_tag="PC592_002795"
     CDS             3474..4223
                     /locus_tag="PC592_002795"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF4056743.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDSELELVCVAARGLDSYEDDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDEEMNKIHEAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            4405..5121
                     /gene="dapD"
                     /locus_tag="PC592_002796"
     CDS             4405..5121
                     /gene="dapD"
                     /locus_tag="PC592_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDF4056744.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     CNGSYIFVGDYEDIMEVLDKHGNDIIDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(5404..6393)
                     /locus_tag="PC592_002797"
     CDS             complement(5404..6393)
                     /locus_tag="PC592_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDF4056745.1"
                     /translation="MLKEEKTYQEKEAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLIFGLIFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAASRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            6836..7591
                     /locus_tag="PC592_002798"
     CDS             6836..7591
                     /locus_tag="PC592_002798"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF4056746.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELKLVCGVARSADEKSHHS
                     DTKLYKTMTDVTEKADVIIDFSHHETLEPILSYALKNNTPVVLATTGYDESDLSKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIKEVLPESTNTHGRYGRDCKRKANEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLVGKQSGLYKMSDILG"
     gene            complement(7865..9550)
                     /gene="bclA2"
                     /locus_tag="PC592_002799"
     CDS             complement(7865..9550)
                     /gene="bclA2"
                     /locus_tag="PC592_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HDF4056747.1"
                     /translation="MSDISGPNLYQDVGPTGPTGPTGATGPTGPTGPRGATGATGANG
                     ITGPTGNTGATGANGITGPTGNMGATGPNGATGSTGPTGATGATGANGITGPTGNTGA
                     TGANGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLT
                     GATGATGANGITGPTGNTGATGANGVTGSTGPTGSTGATGPTGAVGATGANGVTGATG
                     PIGATGPTGADGEVGPTGAVGATGPDGVIGPTGPTGATGATGANGLVGPTGPTGATGA
                     NGLVGPTGPTGATGVAGAIGPTGTVGATGPTGADGAVGPTGATGATGANGATGPTGAV
                     GATGATGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGPIG
                     PTGPTGANGVTGATGNTGATGANGATGPTGATGATGVLAANNAQFTVSSSSLGNNTLV
                     TFNSSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNF
                     IAKAVNTLTSSDVSVSLSFLVDTRAAAVTLSFTFGSGTTGTSPAGYVSVYRIE"
     gene            complement(9907..10446)
                     /gene="hpt"
                     /locus_tag="PC592_002800"
     CDS             complement(9907..10446)
                     /gene="hpt"
                     /locus_tag="PC592_002800"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF4056748.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLKELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(10775..12082)
                     /locus_tag="PC592_002801"
     CDS             complement(10775..12082)
                     /locus_tag="PC592_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF4056749.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDSAEKVESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(12506..14281)
                     /locus_tag="PC592_002802"
     CDS             complement(12506..14281)
                     /locus_tag="PC592_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4056750.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKDLFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDNITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLKERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVRSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(14278..14415)
                     /locus_tag="PC592_002803"
     CDS             complement(14278..14415)
                     /locus_tag="PC592_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056751.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(14493..15062)
                     /locus_tag="PC592_002804"
     CDS             complement(14493..15062)
                     /locus_tag="PC592_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF4056752.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(15246..15881)
                     /locus_tag="PC592_002805"
     CDS             complement(15246..15881)
                     /locus_tag="PC592_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF4056753.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
BASE COUNT         5220 a         2671 c         2237 g         5929 t
ORIGIN      
        1 aactatacct attaaaatta attaatttgt actataatta ttattgtact taaaaaatta
       61 aatttagata aaaaaggaga tttgattata tgttatttaa aggttctgct gttgctttag
      121 ttaccccatt tacagaggat aataatgtca actttgaaaa attaggtgaa ttaatcgaat
      181 accacattga gaatgacaca gatgcactag ttgtttgtgg aacaacaggt gaggcgacta
      241 ctatgagtga atctgaaatt tttgctgtaa taaaatatac agttgaaaaa gttaataaga
      301 gaatacctgt tatagcaggt actggttcaa acaatactat gttgtctgtt catatgagtc
      361 aagaagctga aaaattaggg gtggatggtc ttttaataat aactccttac tataataaga
      421 ctaatgaaaa aggtcttaaa cttcactttg aaacaatagc aaatagtgtt aagttgccaa
      481 ttattttata caacgtacca ggaagaacta aagtgaatat aaagccatct gttgtggctg
      541 aacttgctaa aatagataat atagttgctg tgaaggaagc aagtggagac ttagctcaag
      601 ttgcagaaat agctaaacta gtacctgaag actttgctat atactccggt aatgatgata
      661 ctatactacc actattatca ttaggcggaa gtggtgttat ctctgttctt gctaacatat
      721 gtcctaaaga aacacatgat ttagtagcta aattctttga aggtgatatt gaaggctcaa
      781 aaaaattaca acttgatatg gatgctttaa ttgctgcctt atttatagaa gtaaatccag
      841 ttccagttaa aactgccatg aacattttag gttttaatgt tggtgattta agacttcctc
      901 tagctgaaat ggaagaaact aatcttaatg tgttaaaaca caaattaaca aattttggat
      961 ttaaatttta gcaatattta tataaataag ttgatttttt cttaaatatg tattattatt
     1021 agaataatca aattttaata tcctattaac ctagggtaga ggtagctgta actaagagta
     1081 tccaatagta gctggcaggt gttaatgatt ggaaaaagga tttacagccg aagaaaatat
     1141 ttcttgcaat aatattttct gggattgcac ataacatgtg taatactgtc acttattttt
     1201 gtaggtgatg agctacaggg tttactttga gtgataaatt agacgtacaa agtatacctt
     1261 tgtacgtttt ttgtatataa ttaaaattgt taatataata ttaaagtttt tggatatata
     1321 aaaatattaa catatcttac ttgtattact aaaatcaaat aaaacaatgt ttttataatt
     1381 taaaattggg gtgaatttat atgaaaaaag taaatgtagc aatagttggt gctactggaa
     1441 tggtaggtag aacattttta aaagtattag aagaaagaaa ttttccaata gaaaatctat
     1501 ttttattctc ttcttctaaa tcagctggtt ctaaagtaat gttttgtggt aaagaatata
     1561 tagtagaaga attaaaggaa acttcattta ctgatagagg catacaaata gcattattct
     1621 ctgctggtgg aagtattagt gaaaagtatg ctccaatagc tgcttcgaat ggaatcttag
     1681 tggtagataa ctctagccaa tggagaatga atccagatgt acctttagta gttcctgaag
     1741 ttaatccaga agccataaaa aatcataagg gtataatagc taatcctaac tgctctacta
     1801 tacaagctat ggtccctctt aaagctcttg atgataagta caaaattaag agagttgttt
     1861 actctactta ccaagctgta tctggttctg gtgttaaagg ggttgaagat ttagagaaag
     1921 gaatgaacgg taatcctact ggattctacc ctcatcaaat ctcttacaac tgtcttcctc
     1981 atatagattc attcactgaa aatggataca ctaaagaaga gatgaaaatg gtaaatgaaa
     2041 ctatgaaaat acttgataac tatgatttaa aaataactgc aactactgta agagttccag
     2101 taaaaaatgg tcatagtgaa tctataaatg ttgagtttaa caatccattt gaattagatg
     2161 atttagtaaa aacacttgaa gaagctccag gtgttgtagt agttgataat cctgctaaaa
     2221 acgaatatcc aactgctgta gaatttgatg atagagatga agtatttgtt ggaagaataa
     2281 gaagagattt tagtgttgat aatggtgtaa acctttgggt tgttgctgac aatataagaa
     2341 aaggtgctgc aactaacgca attcaaatag ctgaaatggc tttatcatac gatttagtat
     2401 aatatacaaa cttgtataaa tatataattt tgtaaaatat taatagtaac tcaaaaacaa
     2461 gcattagaag taactgtaat ataaaacaca aaaataaaaa agaggggatt gattttatat
     2521 gatatttaaa ggttctgctg ttgctctagt tacaccattt acaaaggata acaaagttga
     2581 ttttgacaaa ttaggtgaat tagttgagta ccaaatagct aatggtactg atgctatagt
     2641 atcttgtggt actactggtg aagctaatac tatgactgat gaagaacaac ttgctactat
     2701 taagtatgtt gttgaaaaag ttaataaaag agttcctgtt atagctggaa gtggttctaa
     2761 tgatactatg cactcagtta acttaagtca agaagctgaa aaattaggag tagatgctct
     2821 attaataata actccttatt acaataaagc taataaagct ggacttaagc gtcattttga
     2881 aacaatagct aacagtgtta aacttccaat tatactttac aatgtccctg gaagaacttg
     2941 tgtaaatata agtcctagcc ttatagttga acttgctaaa attgataaca tagttgctgt
     3001 aaaagaagct agtggagacc taggacaggt tgcagaaata gctagtttag ttccagatga
     3061 ctttgctatc tactctggta atgatgatac tatacttcct ttattatctt taggaggtca
     3121 aggagttata tcagtacttg ctaatgtttg ccctcaagaa actcacgatt tggtagctaa
     3181 attctttgaa ggcgatatag aaggttctag aaaattacaa cttggtatgg atgctctaat
     3241 tgcagcttta tttatagaag taaatcctat accagttaag actgcaatga atttattggg
     3301 attcaatgtt ggagatttaa gattacctct agcagaaatg gacccagcaa atttagaagt
     3361 gttaaagaaa gaattagtta actttggact aaaagttaat gcatagtaaa gattaatgca
     3421 tggtaaaatg ataagtttgg tcaaaagtta gcccttaatc ataggaggaa attatgttaa
     3481 aagttatagc aactggttat gatggaaaaa tgggtaagat tttagccgat actataagag
     3541 aagatagtga attagaattg gtttgtgttg cagctagagg tctggatagt tatgaagacg
     3601 accttaaaat ctatgaagat atgagcacta tagttgaaga agcagatgta gttatagatt
     3661 tttctcatca ctctaattta gataatatct tatcttacgt tttaaagact aagacacctt
     3721 tagtaattgc tactactgga tataatgatg aagaaatgaa caaaatacat gaagcagcta
     3781 aagttattcc tgtattccaa tcatataata tgtctcttgg tgtaaatgta ttagtaaaat
     3841 tggttaaaga tgcagctaaa ttactagaag gatttgatat agaaataata gaaaaacatc
     3901 acaacagaaa agtagatgcc ccaagtggca cagctgttat gattgctaac gctataaaag
     3961 aagttttgcc aaacgttgaa aataattatg gtagatatgg ccgtagtgcg aaaagacaac
     4021 caaatgaagt tggtattcat gctataagag gtggaaatat cgttggcgaa catgatgctt
     4081 tatttgctgg agacaatgag gttcttacaa taagccatca agctcaatct cgtggtatct
     4141 tcgcaagtgg ttctatagct gctgccaaat atttagttaa acaaaaacca ggattttata
     4201 atatggacag catgttggga taataatata agtataataa tgcacaatat aaatcaaaca
     4261 tatataatag ataaatttac ttaatactat gtctatataa taaaaactaa ttaaaatata
     4321 aataataaga agtaaatata tactaaaatt gacaaacaag tatataataa aagaaatata
     4381 atgaaataca aggagaatta acaaatggta aatttaaacg atgcttatga aatagcaagg
     4441 tatataaaag aagttaaaaa gaaaacacct gttaaggtat atgtaaatac taactcttta
     4501 catttccaat caactgataa atttaaggta tttggatgca atggttctta tatatttgta
     4561 ggtgactatg aagatataat ggaagtatta gataaacatg ggaatgacat aatagatact
     4621 catgtagaat atgatagaag aaattctgct attcctctaa aaaatacttt aagtgaacat
     4681 gcaagaattg aaccaggtgc aataataaga gatatggtta ctatagaaaa aaatgctgtt
     4741 gtaatgatgg gagctgttat aaatatagga gctgttattg gtgaaggttc tatggtagat
     4801 atgaatgctg ttattggagc tagaggaact cttggtaaaa atgttcacct tggtgctggt
     4861 gctgttgttg ctggtgtttt agagccacct tctgctactc ctgttatagt tgaagatgat
     4921 gttttaatag gagctaatgc agttattctt gaaggtgtta gaatcggtaa aggtgctgtt
     4981 gttgcagctg gtgctgttgt aactactgat gtagaagctg gtgctgttgt tgctggttct
     5041 cctgctaaag ttataaaaat gaaagacgaa aaaacggctg acaagactaa acttatggaa
     5101 gaccttagaa atttagatta attaaatgac aatatattaa ttgaaaagat taattaaata
     5161 ataatatact aatttaaaaa ttaattaaaa ggtgtctcta tatgaattta attcattaga
     5221 gacacccttt tttataatat ttttatcttt tatttatttt tataattctc ttattcattc
     5281 tcatatcatt tttatttctt tctgataagt atttttattt ccttcaattt ttcaatatat
     5341 caatgaaaca aactagcgaa ctttatataa accaataaag taaactacta aactttatat
     5401 aatttaataa atagaactgc tgtttactac tggttgtgca tctttattgc cacaaagaac
     5461 aactaacaga ttacttacca tagctgcttt acgttcttca tccaaagtta caacattatt
     5521 ttcacttaaa ttagtcaatg ccatctctac catacttaca gccccttcaa caatcttttt
     5581 acgtgctgct attatagcct ctgcttgttg acgttgtaac attgctgctg caatctctgg
     5641 agcataagaa agatgagtaa ttctcacttc gcatacttca attcctgcaa tatcaaccct
     5701 tgattgtaat tcatctttta atctatctgc tatttcctga ctactaccac gaagagattt
     5761 ttcatctcca tcttcagaca catcatatgg ataaagtctt gaaacattac gaatagtaga
     5821 atcgcactga atagataaaa atgtgttata attatccaca ttaaatactg cctttgttgc
     5881 atctataacc ttccaaatta caacaactcc tattataatt ggatttccca ataaatcatt
     5941 aactttctgt ttttcattat taagagtcat tgtctttaaa gatactttct tacctcttga
     6001 attagttgat atatctactt tttcgtcaga tgaagatttt gatacattaa ttcttgatgc
     6061 tgctgggttt attgctgaac aaaatggatt cacccaatag tacccttctt tttttatagt
     6121 tccataataa ttaccaaaca aaactaaaac tatagcctct ttaggattaa tcattttcag
     6181 cccaaagaat agaataaaat ctactactat aaatataagc ccaaaaatta acataagtga
     6241 acctattcca gtaaatccac tatcaagttt tactatccca aaaaccataa tacctattga
     6301 aactactaaa aataacacaa tcattatcaa agctgctact ccattaaata cttttgcttc
     6361 tttctcttga taagtttttt cttcttttaa catatctatc actcccatct cagtatatta
     6421 agttaagatg tttctaattt aataataaca cttttaacac ttaaattgtt gaatttgaaa
     6481 ttaatactat aatgtattta tatatttttc atacatcttt atacatacat gtgcttagtt
     6541 attttaatgt attaatattg atttttaaat aaattatacg atatatgaat gtggtatctc
     6601 aaaatgaact tttttgattc atgaggttct cttttttgta tgaaaccaaa tatattttta
     6661 tcatttcaac agtgaaaaaa agcttatcta tactttgaca aagctacttc aattttttaa
     6721 tgtaagataa attgtaaacc tattatcact aatattattt tatatagata atattagtga
     6781 taaaataaac ttatagaaat acaacaaatt tttattaatt ttataggagg aatttatgtt
     6841 gaaagttata attagcggct ataatggaac aatgggaaga gtgttagcag aatgtgtaaa
     6901 aaaagataat gaattaaagt tggtttgtgg tgtagctagg tctgctgatg aaaaaagtca
     6961 tcatagtgat acaaagcttt acaaaacaat gactgatgta actgaaaaag ctgatgtcat
     7021 aatagacttt tcacatcatg agactttaga gccaatattg tcatacgctc taaaaaataa
     7081 tacgcctgta gtattagcta ctactggata tgatgaaagt gatttaagta aaatagagga
     7141 agcatcaaaa aatattccta tattattatc atcaaataca tctcttggag ttaatatatt
     7201 aataaaatta gttaaggacg cttcaaagat gttagaaggt tttgatattg aaatcataga
     7261 aaagcatcac aatagaaaag aagacgctcc tagtgggact gctactatga tagctaatgc
     7321 aattaaagaa gtcttgcctg aaagcacaaa tacacatggg agatatggta gggattgtaa
     7381 aagaaaagca aatgaaattg gaatacactc cataagagga ggcaatataa tcagtgacca
     7441 tgatgttata tttgcaggtg ataatgaagt tcttacttta agccatcatt ctcaatctga
     7501 tgaagtattt gcaaacggtt ctatagttgc agctaaattt ttagttggta agcaatctgg
     7561 actttataaa atgtcagata tattaggata aattttgtac ataataaatc tcaatctatt
     7621 tggatattca tattcatcaa tttgaatatc taattgattg agatttctac tctaaaagtt
     7681 tataaatttt atacctactt tttaatatag tcattctgct aaagattata ttattttagt
     7741 atatagaact atattgttca ttattttaca gtattttcac catatagact tattaaaaat
     7801 tatattattt attagtatat aaaatcatat tgtttattat tttatagtcc tttcattata
     7861 taaactattc tattctataa actgatacat atccagctgg agaagtgcct gtcgtgcctg
     7921 aaccaaatgt aaaacttaaa gtaacagctg ctgctctagt atcaactaaa aaacttaaac
     7981 ttacacttac atctgatgaa gtaagcgtat ttactgcttt tgcaataaaa ttattttgag
     8041 ctactccatt gaaattagta gtaattgaca taaatcctgc aagtgaaagt gtggcacgta
     8101 taccaaaaga tacattatat attcctccaa ctgcaagatt tatagtacta cttgttggaa
     8161 aagttatatt agttccattt ataaatgatg aattaaatgt cactaatgta ttattcccta
     8221 aacttgaaga agatactgta aattgtgcat tatttgctgc taacactcca gttgctccag
     8281 tagctcctgt tggaccagtt gctccgtttg ctcctgttgc tcctgtattt cctgttgctc
     8341 cagtcactcc atttgctcca gttggacctg ttggacctat tggacctgct actccatttg
     8401 ctccggttgc tcctactgct ccggttgggc ctgttgctcc atttgctccg gttgctcctg
     8461 tcgctccggt tgctcctgct actccatttg ctcccgttgg acctgttgga cctattggac
     8521 ctgctactcc cgttgctccg gttgctccta ctgctccggt tggacctgtt gctccatttg
     8581 cccctgtcgc tcctgtcgct ccggttggac ctactgctcc atctgctcca gttgggcctg
     8641 ttgctcctac tgttccggtt ggacctattg ccccagctac tccggttgct cccgttgggc
     8701 ctgttggacc taccaaacca tttgctccgg ttgctcccgt tgggcctgtt gggcctacca
     8761 aaccatttgc tccagttgct ccggttgctc ccgttgggcc tgttggacct attactccat
     8821 ctggacctgt tgctcctact gctcctgttg gacctacctc tccatctgct ccagttggac
     8881 ctgttgctcc tattggacct gttgcccctg tcactccatt tgctccggtt gctcctactg
     8941 ctccggttgg gcctgttgct cctgtacttc ctgttggacc tgtagaacct gttactccat
     9001 ttgctcccgt tgctcctgta tttcctgttg gacctgttat tccatttgct ccagttgccc
     9061 ctgttgctcc ggttagtcca gttggacctg ttgctccggt tgctcccgta tttcctgttg
     9121 gacctgttat tccatttgcc ccggttgctc ctgtatttcc tgttggacct gtagaacctg
     9181 ttattccatt tgctcccgtt gctcctttgt ttcctgttgg acctgttatt ccatttgctc
     9241 ccgttgctcc cgtatttcct gttggacctg ttattccatt tgctcccgtt gctcccgttg
     9301 ctccggttgg acctgtagaa cctgttgctc catttggtcc agtcgctccc atatttcctg
     9361 ttggacctgt tattccattc gctcctgttg ctcctgtgtt tcctgttgga cctgttattc
     9421 catttgctcc cgttgctccg gttgcacctc taggtccagt cggacccgtt ggaccagtag
     9481 cacctgttgg acctgttgga cctgttggac ctacatcttg atataaattt ggacctgaaa
     9541 tatcactcat ataattatcc tcccttttta aagttagagt aatactctat aaatattgag
     9601 tattactcta tataattata tgaatcgaca atttcttatg tgataatgta tctatttact
     9661 tatatcaaca tcaattcttt tattcttaga tgtcatcaca tttttataaa atattttaca
     9721 attataaata caattaaaaa attcatttcc caccaatcat ttgaaatttt tttattatgt
     9781 tataaaaaag atatagttga actgcacaag attaatttaa tgctacttta attgcttttt
     9841 aaataaaaaa acctcaacac gattaataaa aatcatatta aggcatccac aaaatcatat
     9901 aattgcttat ctatcttcat cagtgacatt gaatatataa ggaacatttc tataataatc
     9961 gccaaaatca aacccatatc caaccacaaa cttatcttct atttcaaatc cacaataatc
    10021 tggcactaaa tcgacttttc ttctacttgg tttatccaaa agaacacagc attttaaact
    10081 agcaggattt ttagctttta gatgttttaa cacaaaatcc atagtaagtg cagaatcagt
    10141 aatatcatct acaactaaaa catcatatcc tgctatatca gtagtaacat ctgaaactac
    10201 tttaaccttt ccagtacttt cttcattatt tccataacta gatgtagtca taaaattgac
    10261 tctaagtggt aaatttatat ttctaactaa gtctgcacaa aatataaaac taccttttaa
    10321 tagagaaact accataagat ttttatcttt ataatctttt tctataattg ctcctaattc
    10381 ttttaattta tctttaattt tttcttctga atacaacact tcccattttt ttgtttctat
    10441 atccataaaa agacctccaa ttgtaataat ccttcttaat tttataagag attgctcact
    10501 ttttcaatac tcttattcaa tattagccaa tattattgag tttttatgtt cattcaacaa
    10561 ttattaacaa ggtatcttat attttaagta gttcatatat ccatactaaa ttacatacta
    10621 tatattttag acaaaaaaag aaaaaacttg cactaacaag ttttttctat tatacataaa
    10681 tttatacata atcatatttt attagagggt actaattaaa tttatttatg ctgtttttgt
    10741 tattcttcat aatacaaaac catattataa agtactagtc aactttattc atatcattca
    10801 ttacatttaa gattatttca tctgttatag acataccttt gtcacttact ctacctaagt
    10861 tttgtatact ttgctcaaca cttgaaccaa ctataccatt tagtggtggt acaaaacaat
    10921 cttgcttggc tattatagca ctttgtatag ctgcagatgc agcagaagat aattttagtg
    10981 cacaaccagc tttcgcacca tcacatatca ttccacttaa gtcagctatc atattttcta
    11041 tagcaccttc tatttgcttt tcagtaccat tcataagcca agagatacca gcagttgctc
    11101 cagtagatgc agcaacacca catccacata cagcagataa tcttcctgta taattcttaa
    11161 tataaccagt tactaaatga gatatagcta aagcttttgc tagtctttca tcagattgtg
    11221 ggaatttttt attgtaagca acgattggaa gaattgctgt taatccgtgg tttccacttc
    11281 catttgaact cataacaggc atttttaccc ctgccattct tgcatctgaa gctccagcag
    11341 ttaacatcat tgcataattt ataacatcat tgcctaaaag accttcttct atagactttt
    11401 taattccata tccgacacca ataccagttt tttgttttaa tccatattca gccatttctt
    11461 cattcatttt tactccatct agtaaaaatt ctatatcttt aaaatcaatg ccttctacat
    11521 tttttattaa ttcttgtata gttactgtat ccattaaact ttcaactttt tctgctgaat
    11581 catttgaagc tgatactttt ggttcattgt ctaataatac ttctccatct ttttctaaga
    11641 acgtaaaatt atcatgttta gttcttattc taactttagc aatatgattt tttcctttta
    11701 atacaacttc tataaacact ttctctcttg tatcagcagg tgttattgat agaggagtat
    11761 tatccatata atcctcagct attttaactt cctcttttgt tagagtctct aacacactta
    11821 atccgttttc agaatgtcca cctactatac ctagagctgc tgcgattttt aaccctaatc
    11881 tttcagtacc tggtatacct acgcacatac catttttata gatactaggg ctaactaaca
    11941 ttcggttttc aactatttct tctcctaata attcctttgc ctttgcacat gctagagcta
    12001 aagctactgg ttcagtacat cctactgctg gcttaacttc tgcctttaac atttccacta
    12061 attcttttct tatatctctc attatatata aacctcccaa ttaagtttag atttagtact
    12121 caaataatta attaaataat ttcttatcta tatgtatagc aaaatacatg ccatattttt
    12181 tatatctgtt tatattttta attttatatt ctatagccat tggtatgact acttctattt
    12241 atgcattttt tttatttgca taggatattt atattcttta aaatggagaa acatatgaca
    12301 atttcgcaaa aagacaaaaa aaagtctcaa aatgagattc tatatcattt tgagacgact
    12361 caaacatatt attttttaac ttataaaaac tattttttaa ttcataaaaa agattatgca
    12421 aaacacttac aatagaaatt taaatccttc tttaaagtta tacatttaga aaaatttaaa
    12481 ttttatacag ttttttatta tattactatg aaattatatt atatttttca atttttctat
    12541 ataatgtagc tcttgatatt ccaagtgctt tagctgttaa ttctttatct tttttatagt
    12601 ctttgtattt atttaaagct tttattatct caattttctc tagttcatca agtggaatta
    12661 tcctatcgct tctaacttcc aactcttcta cagaggtatt cttaattttt tgaggaatta
    12721 cattcattgt gattattgaa gaggaggaca tattcacact atattcaata atattctgca
    12781 actctcttat attccctggc cacttatatt ccatcatagc atccacaact ctgctatcta
    12841 tgtcaataac atttttatct aatttttttg aatactcttt aaccatatgt ttgattataa
    12901 gtgggatatc ttcttttctc tcttttaaac ttggtaattt tataggtata acatttaatc
    12961 tataatataa gtcttctcta aaagttccat tttgaaccat tttttctaaa tctttatttg
    13021 ttgcagcgat aattcttaca tctattgaaa catttgattt acttccaatt ttattgagtt
    13081 ccttttcttg taatactctc aataactttg actgtaaatg caaactcata tctcctattt
    13141 catctaaaaa tatacttcct ttatgagcta cttcaaacat tccaagcttt ccaccttttt
    13201 tagctccagt aaaagctcct tcttcatatc caaataattc actctctaat aaattgtctg
    13261 gtatagcagc acaatttaca gctataaaag gattatctac cctattgcta tggttgtgta
    13321 tggctcttgc aaatagctcc ttacctgttc cactttcacc agtaataagc actgttgatg
    13381 ttgatttaga agctattaaa gcctcttttt tagaatttct tatagctaca ctttccccaa
    13441 ttatattttc caattttatc ctataatctt tattcatctt attgtagttt tttatagcat
    13501 ctcttttatc tataaaatca ataacatatc cctttaactc attttttaag actattttat
    13561 tgatgttata tattcccttt gaatcatatc cgtatctttt ataaaaaaaa ctacaggatt
    13621 tatccttctt aaagttattt atagaaggtt tctttataaa atctaattcg acaaatatgt
    13681 ttttaccagt tatattatct tttatattga aaagctcttt aaatttcgaa ttatatttat
    13741 caatctttcc gtctacatca atagacacaa cagctttgtc catattgttt aacagtgtct
    13801 ctaatttttt cttttctaat tcaagctcat acgttttaat ttgagctttt aatttattag
    13861 atattaagtc tgccattttg cctaaaaagt ttataagacc acttttatta ttttctataa
    13921 tctgtgcttg ttcctttgta aaggctataa ggcctataac accatgagag actccatcac
    13981 atataatggg acaacacacc tctgcaaact ctacacaagc cccactttta tagcattccc
    14041 tacatatatc actactcttt gggtcatcaa ttagtattgt aatctgctct gtaagtgatt
    14101 ttttaaaagc cgtatattta tctactttct cacctatttt gtctatatat actcctgtac
    14161 ctgcaatcct aaataagtcc ttatttacta tagttacatc tatattgagt actgatacta
    14221 tagcttcagc tatattttga atatcagatt ttatatattc taaacctatc ataatcatca
    14281 ttccttattt ttctttaaca taagtatttg tcttatttct ttaagaatca agtatatctt
    14341 atttaaagta aattggattg acattaggat tacaaagagc ataacaatta ttattaactc
    14401 ataatttatt tccatctaaa catctcctta taacaaaaga ctaggcttaa cctagtcttt
    14461 tatattatat ccatatttat attttaactc atttatcttc tttttcccac ataaatatat
    14521 tttaatttat ttgactcttt aatcatacca tcaaagttta atcttgaaaa tatattgaac
    14581 acttcatgtg gatagtgaat ctttgcaaca gaaccacaaa atttatgttt aagataattt
    14641 aacttaactt ttaaattctt taagtttaaa tcctctaata taacctctcc attgcccttt
    14701 agtactcttt gtatttcaga tgaagctttt tcacaatctg taataacatt aaattggtca
    14761 actattatta tcttgttgaa ctgattatca tcaaacggta gaaactctaa cttaccttta
    14821 actacattgc aattttcatt atacactaga gaataacata catcttcata gttactattc
    14881 tccagtatag ttacagaagt tccaagacct ctcaatctct tgcctaggtt tcctatatga
    14941 ccaacaagca atattttatc acctacatta tactcaattg tatccaaaaa acattctaat
    15001 tcatcagatg tatatttagc tttaactggc tgtttattta tctgacataa tatgcttttc
    15061 acaatgcttc acctcttcat ttcctcaatt ataaattatg tacagattac attataataa
    15121 atggcgagca actattcaag agatatttca ttagtatttt tttaaacaat ctttatatat
    15181 tttaatatga tattatacca aacttattag gattttattc ataaaagtca gtctactttt
    15241 tatgtttatt cattgttatt ttcatccaat ttttttattt tcgatataga tacttcatat
    15301 gccatttttt taaccacatt attttcatct atttttttct catattctct actttgaacc
    15361 ctaccccaaa gctgtatcct atcaccaacc tttagattct ttgcaaactt agcatttcgt
    15421 ccccaaacta ttgatggtat ataatcagat ttattataag gtctgtttat agcaactaat
    15481 aaatcggtta tttcccttcc taaaggtgtc ttcctatata caggttcctt acatacatat
    15541 ccatctaaaa atatactatt agggtcttta ttttcctcgt ctatgctttt tatttctctg
    15601 acaaacactg taagcactaa tctattttta ttatttaatg ttttattata tgatcttaat
    15661 tgacctacga cattgactaa attttgttta tcaaggtcaa tatcttggag aagtctttct
    15721 gatacagtca ttggaagtat atcaaaagaa tcgcttaatc tgtttatttt tattttcata
    15781 ttataaaatt tttctccaaa tatctcatgg ctaaattcta gcttattgtc taactcccct
    15841 cttaagttta ctacgttatt ctcatcttta acagctatca tattttatcc ctccacaatt
    15901 gttaattctt atatttctgg tatcagctta tataataaat atatttataa gggatgtatt
    15961 ttattacaaa tctttgattg ctgtttaaaa gtttttattt ggttataaat ttcatttaat
    16021 atttcacttt tataattata aaattactat ctttttg
//
LOCUS       DAMKOJ010000077        16009 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.083, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000077 DAMKOJ010000000
VERSION     DAMKOJ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16009
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.083"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            183..821
                     /locus_tag="PC592_002806"
     CDS             183..821
                     /locus_tag="PC592_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4056754.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            828..1670
                     /locus_tag="PC592_002807"
     CDS             828..1670
                     /locus_tag="PC592_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDF4056755.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGILQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            1731..4358
                     /locus_tag="PC592_002808"
     CDS             1731..4358
                     /locus_tag="PC592_002808"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF4056756.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRKEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDNALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGVEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            4572..4817
                     /locus_tag="PC592_002809"
     CDS             4572..4817
                     /locus_tag="PC592_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF4056757.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKR"
     gene            complement(5107..6417)
                     /locus_tag="PC592_002810"
     CDS             complement(5107..6417)
                     /locus_tag="PC592_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDF4056758.1"
                     /translation="MNKKVSKIVAIGCGVGIITANLIPVYADNSTSSINKVDNSIVSD
                     STKRTSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFP
                     YDQIGLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMK
                     LKKDLGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEY
                     RFESFRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVA
                     PTKPEQGNLTDDEYKVLMDKYGKDYDRYKKEVEEYNLERQTYAAGLTTYANYLQQKYN
                     TENGLVTLEDNKKALKKGLIDSYAQLLALEDTIQITKKQLELSEKQLKNTKLRYDLGL
                     ITLTDYKKQVVSNEDAKNNYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(6439..9573)
                     /locus_tag="PC592_002811"
     CDS             complement(6439..9573)
                     /locus_tag="PC592_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDF4056759.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQIGQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     NNLLISSVIAFIVIFAFLKSVRASLVVAIAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSIDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTDGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDTPLFDK
                     VSELYKRLLSVCLRHQRLVVISSLLIFIASLFGMSFIGMDFMPAADKGELAISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNNTANIAIELESQKNRKRSTDE
                     VEKEIIDRVATVPDCKINVSQNSSVMGGTSGADFTLEMKGPDLDVLKILGKEAEKQFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGINTAEIAGLLRTAINGDSVTTATIDD
                     YKVDVNLKFKADSIDNLEDIKQLKVNSTTGKEVPLGAFSDIKMADGLQSISRTDGNFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGQTEMMNESMASLGFSMLIAI
                     VLVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTISTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGDI
                     KRKIIKKPKLKAKV"
     gene            complement(9577..10800)
                     /locus_tag="PC592_002812"
     CDS             complement(9577..10800)
                     /locus_tag="PC592_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF4056760.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEEPEPEKPIAVSVQKAVGGEIE
                     NTNAFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPDLENSVKQSK
                     AALDLAKASYSSTTGGSLEAQVNQAKTALDNAKIQYDESQRNYDNNKILYEQEVISLD
                     QFKKIEFALEQSKQQLDSAQRSYDTVTSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTAPVDGTITAKNFDAKEMITQSQPAFIISNPNILEVNLNVAESDIDKFKKDGNVE
                     VIIEDQRILGKIDYVPSVVDPQTSLYPIKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEEKGKKYVYIANKDNIAKKKLVQTGIVTEDKIEIKSGVSEKDTVVIGGIS
                     LISDGTKIFPVEKEK"
     gene            11052..11537
                     /locus_tag="PC592_002813"
     CDS             11052..11537
                     /locus_tag="PC592_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4056761.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFRESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFELFGAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            complement(11648..13876)
                     /locus_tag="PC592_002814"
     CDS             complement(11648..13876)
                     /locus_tag="PC592_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HDF4056762.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFIPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAETGEYKGKYIKGKESKFDTLEDANKIIASIASKTGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKNLSKDEQLVYDA
                     IKDRFIANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKINQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEEYTFDSKTKKFTKTKEKKQKKDTTNA
                     EKEVAISKDSNNKKESKNGDENQPLGKCPVCQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDALLKYNKNPDTGYFNWKIEF
                     DN"
     gene            13989..14420
                     /gene="dut"
                     /locus_tag="PC592_002815"
     CDS             13989..14420
                     /gene="dut"
                     /locus_tag="PC592_002815"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDF4056763.1"
                     /translation="MYTLKVKKINDDAIIPNFAHKGDAGMDLYSIEEVVIPSGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIIKPIYDINIEEVEELSDSERGKGGFGSTGF"
     gene            14680..15870
                     /locus_tag="PC592_002816"
     CDS             14680..15870
                     /locus_tag="PC592_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF4056764.1"
                     /translation="MNFNQKRIAASVMATAIIIPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKDGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTSENTGNSSNDIVKGTKVVTAKSLNLRTGPGTSHSKIATL
                     SYGTEVGRISENGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGAESVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLIFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
BASE COUNT         5558 a         2276 c         2530 g         5645 t
ORIGIN      
        1 atatagttct attaattaaa gaaatatccc ccattaatat ataataaata tctttaagcg
       61 agagaactta gtaaaaaata tatcgtattc aataaaaaat ctgtttacag aatggtatat
      121 atagttatat aatatactat ataagatgcg aaaagataaa aagtatagca caatgaaaga
      181 aggtgattat tattcagctt aatgaaagac aactaaaaat tatagatata gttaaggaaa
      241 atgaaccaat aacgagtgaa agtattgcct ccagcttgaa tgtgactcgt gctacactta
      301 gatctgattt agctatatta acaatgacag gaatattaga cgcaagacca aaagttggat
      361 atttttattc aggagttagt gaaataaatt taattggtaa gagtgtaaaa gaaaaaacag
      421 tagaagatat aatgagcatg cctgtactag ctaagaaaga cgaaagtata tatgatgtaa
      481 tagtcactat gtttttatct gatgtaggga gtatagttat tatagatgag aatgaagagt
      541 tatgtggagt tgtttccaga aaagacttgt taaaagcaac tataggaggt tctgatataa
      601 ataagatgcc aataggtatg ataatgacaa gaactccaaa tgtagtaact ttaactaaag
      661 gagcaagtgt tttattagct tcaagaaaaa taatagaaca tgaagtagat tcgattccaa
      721 ttgttgaata taagggagaa gacaaaaatc atatgagagt tgttgggaga atatcaaaaa
      781 ccaacataac taagctattc ttagaaatag ttgacaatta aggaggtatg ctggtgaaaa
      841 acctaattat atatgcagtg tcagattcag taggggagac tgcacaacaa gttgcaaaag
      901 catgtatgtc tcagttttat gtgaatgaaa cttatgaaat aaaaagattt ccatacatga
      961 ttaataaagg agtactactt gaaactttgg agaatgcaaa agctgaaaac gctttgattg
     1021 tatatacatt agttgatgaa gaattatgca gtattgttga aagatattgc gaaagagaag
     1081 gacttagttg catagactta atgacagata tactaagaga aataagcaag agaacaggaa
     1141 gaaaacctaa aagagaagct ggtataatta gaaaattaga cgaatcttat tttaagagag
     1201 ttgaagccat agagtttgca gtaaaatatg atgatggaaa agaccctaga ggtattcttc
     1261 aagcagacat aattttagtt ggaatctcaa gaacgtctaa aactcctttg agtatgtatt
     1321 tagctaataa aaatataaaa gtagctaatg ttccattagt tccagaaata ccaattccta
     1381 aagaagtgtt tgagatagat actaagaaga taataggtct tactaattca cctgaaaagc
     1441 tgaatgagat aagaactcaa agattaaaag ccttaggttt atctagtaaa gcaaactatg
     1501 ctaatttaga aagaatactt caggaattag attattcaga agaaataatg aaaagaattg
     1561 gatgcccagt aataaatgtt tcaaataagg caatagaaga aacagcaggt ataattttag
     1621 acataatgaa agaaaatggt ctaaagatat acaaagaaat agaaatttaa taatgtctat
     1681 taataaaaat gatataaatt aaaataaaaa gattaatggg ggatttaaca atggaaacta
     1741 agtatgttta tagttttggt gaaggaagca aagacatgaa atctttacta ggaggtaaag
     1801 gtgccaattt agcagaaatg actaagatag gcttacctgt ccctcctgga ttcactataa
     1861 caacagaagc atgtaatgat tattatgtta acaatgaaag tataagaaaa gagataataa
     1921 aagaaataga ggagcattta gctactttag aaaaagattt aaataaaaca ttaggatgca
     1981 ataagaatcc attattagta tcagttcgtt ctggtgcagt attctctatg ccaggaatga
     2041 tggatacaat tcttaaccta ggtcttaatg acaacagtgt tgttggtcta gctgaggcta
     2101 cacaaaatga aagatttgca tatgatagtt acagaagatt catacaaatg ttttctgatg
     2161 ttgctatgga agttccaaaa tataaatttg aaaatgtatt agacagagta aaagaagcaa
     2221 aaggatatac agttgataca gagcttacaa ctgatgattt aaaagaaata gtaaaagaat
     2281 ttaaagcaat ttacaaaaaa gaaataaaaa atgatttccc acaagaccca aaagagcaat
     2341 taatgcttgc aatagaggct gtatttagat catggaataa tcctcgtgca atcgtatacc
     2401 gtaaattgaa tgatatagct cataacttag gaacagcagt aaacattcaa tcaatggtat
     2461 ttggaaatat gggagaaact agtggtacag gtgttgcatt tactagaaat ccagctacag
     2521 gagaaaataa attatttggt gaatttttaa tgaatgcaca aggtgaagac gttgttgcag
     2581 gtataagaac tcctcaaaat atatcaactc ttgcagacgt aatgccagct gtatttgatg
     2641 aatttgtaaa aattactcat atacttgaag gtcactataa agatatgcaa gatatagagt
     2701 ttactataga aaatgaaaga ttatatatat tacaaactag aaatggtaag agaacagcag
     2761 cagcagcaat aaatgtagca gttgatttag ttgaagctgg aataattgat gaaaaagaag
     2821 ctataatgag aattgaacct aatcaattag accaattatt acatccaaaa tttgaagata
     2881 atgcgttaaa agaagctaag gttatagcaa aaggtttacc agcatcacca ggtgcagcaa
     2941 gtggtaaagt ttatttcaat gctgatgatg tagtaaaagc aaatgaaaaa ggagaaaaag
     3001 tagttttagt tagactagag acatctccag aagatataga aggaatggtt aaagcagaag
     3061 gaatccttac agctagaggt ggaatgacat cacatgcagc agttgttgct agaggtatgg
     3121 gtaaatgttg tgttgctgga tgtggagaaa taaaagttga tgagtttaat aaagaaataa
     3181 gagcacttga tgatgtagtt ataaaagaag gagaatatat ttctatagat ggttctacag
     3241 gaaatgtgta cctaggagat gttaagaaaa cagaagtatc tttaactgga aactttgaaa
     3301 aattaatgaa ctgggtggat aaacacaagt gtatgatggt tagaactaat gcagataatc
     3361 ctagagatgc tcgtgcagct atagaatttg gtgctgaagg tataggttta tgtagaactg
     3421 agcatatgtt ctttgatgaa gctagattgc cagcagttag agaaatgata ttatctaaca
     3481 cagtagaaca aagagaaaaa gctcttgaaa aaatattacc aatgcaaaga gaggattttg
     3541 tagagttatt taaagttatg gatggaaagc cagttaatat aagattatta gacccaccac
     3601 tacatgagtt cttacctcat gatgatgaga ctatagaaga actttcaaaa tctatgggaa
     3661 taaaagtaag tgatattaag aagagaatag ttgatttaga tgagtttaac ccaatgcttg
     3721 gacacagagg ttgtagactt gcaataactt atcctgaaat atgtgtaatg caatctaaag
     3781 ctataataca aggtgctata gaagcaatca aagcaggggt taaagtttct ccagagataa
     3841 tggttccatt agttggagaa gtaaatgagt taaaaataat aagaaaaatg atagtagaaa
     3901 ctgttgatgc tataataaaa gaagaaggcg tagaagttcc ttatactgta ggtactatga
     3961 tagaaatacc tagagcttgt ttaactgctg atgagatagc acaagaagca gacttcttca
     4021 gttttggtac taatgactta actcaaatgg catttggata ttcaagagat gatgctggta
     4081 aattcttagg tcaatatgta gatgaagaga tattagaaaa agacccattc caagtactag
     4141 accaaaatgg tgttggtaag ttagttaaga tgggagctaa attaggtaga gaagttaaac
     4201 cagaattaaa attaggaata tgtggagagc atggaggaga accatcttca gtagagttct
     4261 gttatagtgt aggacttaac tatgtatctt gttcaccatt tagagtgcca attgctagac
     4321 ttgcagcggc tcaagcatct ataaaaaatc ctagataata atagaatgta aaatatgtaa
     4381 ctaaataaaa ataatatccc ctattgttca atgtatcaaa tctagtattt gtaagttgaa
     4441 tataggggat ttttattata aaaatttaac ttatatggtt gtaagtgaaa cgtatttaat
     4501 tatattgcat atattattgt agagagaaat tttaactatt aattaaattg agtttactgg
     4561 aggggataaa gttgacaaag tgtcctaaat gtggaaagga agtatcatca cgtccaggta
     4621 gtatatgccc acgatgtgga tttaaggtag cagatgagag tctaaaaata agatgtccag
     4681 aacctagttg tagggctttg gtatctagga aactggatta ttgtcctaaa tgtggatgca
     4741 aacttagagg atataatatt tctgaatttg ttaacatggt gagatgtaaa atagatgaga
     4801 catttgataa aagataatta aatttaaagt taaacttttg agggtgtctc aaaatgaact
     4861 ttttagttta tgagacactc ttttttgtat gaaatcaaat atatttttat catttaaata
     4921 gttaaaaaga ggcttatctc cattttgaga tagcctctat aaaagtatac agttttataa
     4981 gtaaatatat ttttgctaat ctatttctat tatttgcctt atgaatcttc catagctaaa
     5041 gtcataagtg tgcatagcta ttttttaatc aaatgtatgt taaagtaatc tttctattta
     5101 ccagaattac tttccagtat taagtatcca aggtttctct ataccatttt ttagtgagtt
     5161 ataattcaca ataagtgtgt catagttatt tttagcatct tcattgctta caacttgttt
     5221 tttataatca gttagagtaa ttaatcctaa atcatatctt aatttagtat tttttaattg
     5281 tttttctgat agttcaagtt gttttttagt aatctgaatt gtatcttcta aagcaagtaa
     5341 ttgagcataa ctgtcaatta atcctttttt aagagctttt ttattgtctt ctaacgttac
     5401 tagaccattt tcagtattgt atttttgttg aagataattc gcataagtag taagaccagc
     5461 agcataagtc tgtctttcaa gattgtattc ttcaacttct tttttatatc tatcataatc
     5521 ttttccatac ttatccataa gaaccttgta ttcatcatca gttagattac cttgttctgg
     5581 ttttgtagga gcaactggtc ttgtaagatt aggtctatct ggtaaatctg ctttgttctc
     5641 atctttatca ttaaaacttt cttctgtacg ttctaaaatc aattggtcgt attttaaata
     5701 ttcattaacc ttgccttcca tatatgaatc aactgagcca cctactctga aagattcaaa
     5761 tctatattct ttatctaatt gataattatt taaatctata ttagtcaata atttaaaata
     5821 gtcttgatta ttttttagtt cttgaagctt agctttttga gtattttgta gtgtttgaag
     5881 ttcaagttca gctgactcag tttctaaaga tgttactagc cctaaatctt tttttaattt
     5941 catatcttta atttctttag tttttatctc aagattattt tttatcttat ctaactcatt
     6001 ttctcttgaa actaaatcgt taaatttatt agtaatatca ttggctattt ggtcctccat
     6061 aaaaccttta gcctgttcac tttgattttt aagaagtcca atttggtcat atggaaatga
     6121 gttgtcactt ccagtaaaac tatcaaattc atcttgcact tctaactttt cttttaacat
     6181 ttttatttct tctgatttca tttttaattt ttcactattt ttaagtgcag cactaacagc
     6241 ttctctagca gttaaaattt ccttttcaga tgttctttta gttgagtcac tcacaatgga
     6301 attatcaact ttatttatag aagaagtact attatctgca taaacgggta ttagattagc
     6361 tgttattata ccaacgccac agccaattgc aactattttg ctaacttttt tattcaatac
     6421 aatcaccctc cattctattt aaactttagc ttttaatttt ggtttcttta ttatttttct
     6481 ttttatatca cctattttat ctgttatttt accaaatatc ttaggcattt tgtctgaaaa
     6541 cttattttcc catttatcaa atatcaagta tatagtaggt ataagtacca aagttataag
     6601 tgtagatata gtcagacctc ccattataac tattgccagt ggttgcattg tttctccacc
     6661 ttcaccaaga gatagtgccg ttggtaacat acctaaaatt gttgttgctg tagtcattag
     6721 gactggtctt aatcttgctg cacaaccaat tgaaaccaaa ccaattaaat cattattacg
     6781 atttgttttt ctaagttgct ctatgtagtc aataagaact ataccattgt taacaacaat
     6841 acctataagt aagattatac ctagcatacc tacagtactt aaactttgtc cactaactag
     6901 aagagaaagc acaactccaa cgaatgcaaa tgggacacag aacataatta taaatggttt
     6961 actaaatgat tcaaactgag ctaccattac catataaact aatactatag ctatgagcat
     7021 tgaaaatcca agactcgcca tagattcatt catcatctct gtttgaccac caacaccaat
     7081 agaataatct ttaggaatta ccattttatt cgttttttct agtgctagtt ttgtagcagt
     7141 accagcatct aaattgtcaa gtgtagcagt tatatttaca gagaaatttc catcagttct
     7201 agatatagac tgtaaaccat ctgccatttt tatatctgaa aaagcaccaa gaggaacttc
     7261 ttttccagtt gtagagttta cttttaattg ttttatgtct tctagattat caatactatc
     7321 tgctttaaat tttaaattta catcaacctt gtaatcatca atagtggcag tagtaactga
     7381 atcaccattt attgctgtac gcagtaatcc tgctatttca gcagtgttta taccatattc
     7441 ttgagctttg tgtttgtcta ttgtaaattg agcttcttgt gttgtatctg taagagaagt
     7501 ctcaacattt ctaaatcctt ttatagagct gaattgtttt tcagcttctt ttcctaatat
     7561 tttcaataca tccaaatcag ggcctttcat ttctaatgtg aaatctgctc ctgaagttcc
     7621 acccatgaca ctactatttt gactaacatt tattttacag tctgggacag tggcaactct
     7681 atcaattatt tctttttcta cctcatcagt acttctcttt ctattttttt gtgattctaa
     7741 ttcaattgct atatttgctg tattattatt tgaatctgat gtcaaagttg ttattaaagt
     7801 tttaatctct ggaatatctg aaactttttt ttcagtcata gatacatagt aatcattaga
     7861 ttctagacta agaccttttg gaagttctat agaaatagcc agttcacctt tatctgcggc
     7921 aggcataaag tccataccta taaagctcat tccaaataaa gaagctataa aaataagtaa
     7981 acttgatatt actactaagc gttgatgtct taagcataca cttagtaatc ttttatataa
     8041 ctcacttact ttatcaaata aaggagtatc tttttcttgc attttttgac tattcttgcc
     8101 tctacttaat tttgcaaata cactagggac aagagtaatt gcacctatga aagagaaggc
     8161 tagggaagct attagtgttt tacctaatgc accaaaggtt attttggcta taccatctgt
     8221 aaacataata ggtaaaaata ttgctatagt agtcaatgtt gatgcaagta ttgcatttgt
     8281 tacagttctt gttccttcaa tagcacaatc atcaatactc aatctaccgc ttttcctata
     8341 tttaaatata ttttcaatta caactgtggc attatcaaca accataccaa ccgaaattac
     8401 cagtgaactt gcagtaataa gatttaaact ttcaccagta aagtagagaa ttgctatagc
     8461 acctattata gaaattggta ttgcaatcgc aacaaccagt gaagctctta cacttttcaa
     8521 gaaagcaaag attacaataa atgcaataac agaacttata agcaagttgt tcattacact
     8581 gtttattgat tcacttatgt atgaacttgt gtcgttagca attttaattt taaattgggg
     8641 attttcttta tttaattcat ccacatattt gtatgcactt tgcataactt ttacagtatt
     8701 ggcatcttgt tgtttagaaa tatctattac caaactgtct tttccattgt atctgtaaat
     8761 actatctttg tctgcatatc cataatctac actacaaaga ttatctaatc taactgtatt
     8821 tccacctttt acaggaattt gaatctgttt tatatcatct agcgattcca acttatcaat
     8881 tgctcttaaa actattttat cttcaccttg agtaattgaa ccataaggga atgttttatt
     8941 actagaggat agtacacctt ttatagtgga taaactaact ccataatttg aaagaacagc
     9001 tgggtcagct attacattaa cctgtgcttt ttctccacct ttaaggtctg ctgatgtaac
     9061 accatctatg gattctattt taggttgaat cacatcttca gcatattttc ttaatgcttg
     9121 tgaactattt tcatttcctc cagatataac aagttgacct atagcttgtg cattcatatc
     9181 caactttaaa acagttggtt tagctgcatc atctggaaga ctagtttgta atgcatcaac
     9241 tttagaccta acatcattca ttatttcatc taaattagtt ccaaattcaa attgagccac
     9301 taccatagaa acactctctt gtgaacttga tatagtagat tttacatttg aaacagctga
     9361 taaactttca tcaacttttt gaccaatttg ttcatcaaca tcttgaggac cagcacctgt
     9421 ccaagtagtc atgaccatta caacgggtat ttctatatct ggcatcagat ttattgacat
     9481 tttcttatat ccaataccac caaaaactat taatactaaa aataccatta taattgtgag
     9541 aggacgttta acggaagttt gtgttaaatt catagcctat ttctcctttt ctacaggaaa
     9601 tatcttagtt ccatcagaaa taagacttat ccccccaata acaactgtat ctttttcact
     9661 tacaccactt ttaatttcta ttttgtcctc tgttacaatt ccagtttgaa ctaatttttt
     9721 ctttgctata ttatccttat ttgctatgta tacatatttc tttccttttt cttcaaatat
     9781 agccttttta ggtactgtaa cggcaccatt ttctttttca acacttaagt ttacttgggc
     9841 agacattcct gctttaaatt tgttgtttgt gttattaaca agcactttaa taggatataa
     9901 agatgtctgt gggtcaacta ctgaaggtac ataatctatt tttcctaaaa ttctttggtc
     9961 ttcaattata acttctacat ttccatcctt tttaaattta tctatatctg attctgctac
    10021 atttaaatta acttctaata tgttaggatt agaaataata aaagctggtt gtgattgtgt
    10081 tatcatttct tttgcatcaa aatttttggc tgttattgta ccatctactg gagctgttaa
    10141 tgttaattta tctaaattac tcatagctaa attatatgat acttgtgctt ggtcaagttg
    10201 ttttttagca agagctttag cttgtggtat actctttgaa gttactgtat cgtatgatct
    10261 ttgagcagaa tctagttgtt gctttgattg ttctaaagca aattctattt ttttaaattg
    10321 gtctaaacta attacttcct gctcataaag aatcttatta ttgtcataat tcctttgaga
    10381 ttcatcatat tgaatctttg cattatcaag tgctgttttt gcttgattta cttgtgcttc
    10441 taatgaacca cccgttgtac ttgaataact tgctttagcc aaatctagtg ctgctttact
    10501 ttgttttaca ctattttcta gatctggact gcttatactc aataattcat ctccctttct
    10561 tacattttgc ccaagtttta cataaacttc ttgaactgtg ccaacagtct gtgcagtaac
    10621 agctgtttca tctttaacct ttgtagttcc tgaaaaagca tttgtatttt caatctctcc
    10681 tcctactgct ttttgaacag aaactgctat tggtttctca ggctcaggtt cttctgtttt
    10741 tccacatcca actaaaaaca gtgaactaca cattaagaaa actattaaat atcttttcat
    10801 atctcctcct attatatatt gcacactaac ttgttgtaga atttaaagtg tctcataatt
    10861 caagtttatt tttaggctaa ttaaaaaact ttcttttatt ggcaatttat aattctctaa
    10921 tttgattata aatttataat tattatgagt caataacttt ttcttgtttt aaatttgtta
    10981 atagtttata atttatatta tataagtaac aaatgtttta ttacatcatt tattgaaggg
    11041 atgttacaaa tatggataat aacaatatac ttaaaatagc agactctttt ttagactttt
    11101 tatttgtgct tgaaaataat atatttagag aaagtgattt gttaaaaaaa tttcaaaata
    11161 actctgatat aatgaaagcg tattttgaag aatgtccaat ggctccatca catgctaagg
    11221 taattcttta tctcatgaca tcaaattcat catcaatatc tcaaatagct tctaatttag
    11281 gaattttaaa atcaaacatg acaccgatta ttgacagatt agtggaacat ggtttagtaa
    11341 ataaatttcc tgacccaaaa gatagaagga ttcttagggt tgaattaacg gataaagcat
    11401 ttgaattatt tggcgcagta aaagctattc tcaaagaatc tctagtaaaa aaattatcta
    11461 atctttctga ggaggaacta actttattag atgaacatac attaaagtta tcagaaatag
    11521 taaagaaatt aggttagcat gtggttgtaa aagtcattat taaaaaactt aaaacttcat
    11581 aagaaaagaa atagcagtag tataatatag aatattatac tactgctatt tcttttctta
    11641 tgaatattta gttatcaaac tctattttcc aattgaaata gccagtatct ggatttttat
    11701 tatactttaa taaagcatca aatttattac catttttagc agttaaagat tttactttag
    11761 tttcaccttt ttttaaaata tttttgacca ttgttttgtt aactttcttc ttataaaggc
    11821 ttaaatactt gtcatttttc caaataacaa atttacattc tttatgattt ttacaagcaa
    11881 agcctttgtc aaattccaat acatcacctt gacaaacagg gcatttacca agaggttggt
    11941 tttcatcacc atttttagat tcttttttgt tgttagaatc ttttgatata gcaacttctt
    12001 tttcagcatt agttgtatct tttttctgtt ttttctcttt tgttttagta aattttttag
    12061 tttttgaatc gaaggtatat tcttctgtgt ttatattttt tgaagcatct tgttttataa
    12121 tattgacatt ttgatatata aaactaatga tattagtaag gtattctttt cttgtatact
    12181 ttcctttttg aatatcactc aaactttttt caagtttccc ggtataatct acatcaaata
    12241 agtctttaac aggaaaaatt tcaactaaat ttttcccaag gtctgttata gaataagatt
    12301 ttcctttttt ctttacatag cctacttgat ttatcttctt taatacatca gcacgtgtag
    12361 ctgatgttcc aatcgaatat ccggacaaca ctgttgtgtc ttcttcaggc acatttttac
    12421 cacaattttt catagccttt aaaagagtgt cctcagtata cggtttaggt ggagtagttt
    12481 gcttagttaa tggttttatt tctaacacat ctacaacatc atctttattt acaagtggaa
    12541 gtaaatcgtt tttttcttcc ttattatata cttcaagata tccttttgat ttaagcacct
    12601 taccttttgt taagaaagta caattatcta cttcagtctt aatttctgta ttctcatatt
    12661 cagcaggagg cataaagttt gctatgaatc tatcttttat tgcatcataa actaattgtt
    12721 catccttaga taagtttttt ggaattatat aagttggaat tatagcacta tgagagtcta
    12781 ccttagaaga atcaaagact cttttagttt tagaaaattt aattttattt tcatattcaa
    12841 gaccaacctt taatttatct agagtttgag aagcttttga agccaaactt tcttctaaga
    12901 aaatagaatc agttctaggg taagttatgt atccaccctt accattaccc tcataaagag
    12961 attgacagac atttaaaacc ttatcagatg taaaattgga atacttagaa gttatatatc
    13021 cttgaagtga tgttaaacta aaaagttttg gtgcatattc ttttgacata gtaacttttt
    13081 tatctagtat tttaccagtt ttagatgcaa ttgaagctat aattttattt gcatcctcaa
    13141 gtgtatcaaa tttactttct ttgcccttaa tatatttacc tttgtattca ccagtttcgg
    13201 ctttaaaatg accctctatt tcataataag ttttaggaac aaagtttagt atttccatat
    13261 ccctatcata gactaattta actgttggaa gaattaccct acctatgttt aatagtttcc
    13321 catttccata tttcagtgta gcaacagaag tgaaatttat tccaatcaac caatcagtaa
    13381 taagtcttgt atatccagca gcttgaagat ttctcatctc atcttcgtcc tttaagtttt
    13441 ttatacctct tgtaatgtct tctggtgtcc attcatttac taagattctt tttactggtt
    13501 ttttattttt tgcaagtaaa aatattaaaa atgctataag ttctccttct cggtcattat
    13561 cagtagcatt tattacatat tccacatctt ttctattcaa aagctttttt acagtgttga
    13621 attgtttggt tttagaacta tcaattttaa atttaaattt atcctcagga ataaatggga
    13681 aattgttcat tttccaagag ccagagtatt tatctttatc ataatccttc atatcatata
    13741 atgatactaa gtgtccaact gcataagtaa ttatataatc atttccttca aagtaaccat
    13801 cttgtcttgt ctttgcacct aaaaatgatg ctatagtttt tgccacagat ggtttctcag
    13861 caagtacaag tttcataaaa aatcctcctt taaaacacta ataattatat taccacaaaa
    13921 aaataaaaaa cttcaagagg tcgaaattta agttataata tttatagaaa gttgaaagga
    13981 gaaataagat gtacacttta aaagtaaaaa aaataaatga tgatgctata atacctaatt
    14041 tcgctcataa aggtgatgcc ggtatggatt tgtattctat agaggaggtt gtaatacctt
    14101 ctggagagac taaacttatc aaaactggga tatgtataga acttcctact atgacagaag
    14161 cacaggtaag accgagaagt gggcttgcct taaagcattc tgttactgta ttaaatacac
    14221 caggaactat tgatgaagga tatagaggag agcttaaaat tatattaata aatcatggta
    14281 aaaatgattt taaggttgaa aaacatatga aaattgctca aatgataata aaacctatct
    14341 atgatattaa catagaagaa gtagaagaat taagtgactc tgaaagagga aaaggtgggt
    14401 ttggttcaac tggattttaa aaagttacaa aaaagttaaa aaatatagct attttaaaaa
    14461 aaagcaaaat atggctatat tgctaaatta caggctgtta aggattaaaa tttatacatg
    14521 gtaatttatg gtaaacaaat attactatag acaaatagtt acaaatttgt aataatatta
    14581 atataaaaga aataattgat attttaagag tgtcaattat ttcttttata ttttgaaatg
    14641 aaataaagct agtagaaaag aggagatgag tggaaagtta tgaattttaa tcaaaagaga
    14701 atagcagcta gtgtaatggc aactgcgata ataataccta ctatggggaa tttagcatat
    14761 gctaatgagt ctgaagtaga aagtgtgagt atagaaagca gaacaataac agggaatgca
    14821 gtaaatttta gaaaaggacc aggtacaaac catgaatcaa tggggaaact ttacaaaggt
    14881 gataaagttg agtatgtagg aaaagatggt tcttgggtaa aagttaaata taatggaaac
    14941 acaggttatg tgcatggaaa ttatgtagca ataaatagcc ttggaagtag taatgaaagt
    15001 agtgatactt cagttaagtc gacaaaagtt gtaacagcaa aaggcttaaa ttttagaact
    15061 ggaccaagca caagtagttc taaaatatca acactaggat acgggacgga agtaggatac
    15121 atatctgagt caaatggatg gtcaaaaata agttctaatg gtagagtggg ttatgtttca
    15181 agtaaatatt taggaactag tgtaaatgac tctacaagtg aaaatactgg aaacagctca
    15241 aatgacattg taaaaggtac aaaggtggta acagcaaagt cattgaacct tagaaccgga
    15301 ccaggtacaa gtcattctaa aatagctaca ttaagttatg gtactgaggt tggtcgtatt
    15361 tctgaaaatg gagggtggac aaaagtaagt tatggcaatc aaacaggata tgtatcaagt
    15421 caatatcttg ctgaaaaagg ttctgttgat acttcaattc catcttattc gactaattct
    15481 ccaagccaag gagctgaaag tgtaataagt tttgcaaaga cactacttgg aaaaccatat
    15541 gtgtggggag cagaaggtcc aaatagtttt gactgttctg gattcacaca atatgttatg
    15601 aaaaagtctg caggagttag tataccgaga gtatctagag accaaagcaa gtatggaaca
    15661 tatgtaaata gaggagacct tagaagtgga gatttaatat tctttgatac acaaggttca
    15721 aataatggtt ctgtaagtca tgttggaata tacataggaa atggagatat gatacatgca
    15781 tcttcaggtt catcaaaaaa ggtaacaata tctaatataa atagtagtta ctattcaagt
    15841 agatatgtaa atgcaagaag agttttataa ttatttttta ttacaaaacc taataaacag
    15901 atttttcttt attgcttata atatgaaagc aggtacaata ttgatagtaa tgtatgttat
    15961 aataaatatt actatttgat ttgtacctgc ttttttattt attttctct
//
LOCUS       DAMKOJ010000078        15965 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.084, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000078 DAMKOJ010000000
VERSION     DAMKOJ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15965
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.084"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="PC592_002817"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="PC592_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDF4056765.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="PC592_002818"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="PC592_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDF4056766.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTG
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="PC592_002819"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="PC592_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HDF4056767.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1254..1679
                     /gene="rplK"
                     /locus_tag="PC592_002820"
     CDS             1254..1679
                     /gene="rplK"
                     /locus_tag="PC592_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDF4056768.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1750..2448
                     /gene="rplA"
                     /locus_tag="PC592_002821"
     CDS             1750..2448
                     /gene="rplA"
                     /locus_tag="PC592_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDF4056769.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2500..2628
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2671..3177
                     /locus_tag="PC592_002822"
     CDS             2671..3177
                     /locus_tag="PC592_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDF4056770.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3235..3600
                     /gene="rplL"
                     /locus_tag="PC592_002823"
     CDS             3235..3600
                     /gene="rplL"
                     /locus_tag="PC592_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF4056771.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3969..4757
                     /locus_tag="PC592_002824"
     CDS             3969..4757
                     /locus_tag="PC592_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF4056772.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEDKIDILVNNFGSTNPSLDRDL
                     LTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPAFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5230..8946
                     /locus_tag="PC592_002825"
     CDS             5230..8946
                     /locus_tag="PC592_002825"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDF4056773.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIMKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            8988..12473
                     /gene="rpoC"
                     /locus_tag="PC592_002826"
     CDS             8988..12473
                     /gene="rpoC"
                     /locus_tag="PC592_002826"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDF4056774.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNEKIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKSLGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREVDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12763..13185
                     /gene="rpsL"
                     /locus_tag="PC592_002827"
     CDS             12763..13185
                     /gene="rpsL"
                     /locus_tag="PC592_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDF4056775.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13308..13778
                     /gene="rpsG"
                     /locus_tag="PC592_002828"
     CDS             13308..13778
                     /gene="rpsG"
                     /locus_tag="PC592_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDF4056776.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13827..15893
                     /gene="fusA"
                     /locus_tag="PC592_002829"
     CDS             13827..15893
                     /gene="fusA"
                     /locus_tag="PC592_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF4056777.1"
                     /translation="MARKFPLEKTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFINKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6254 a         1999 c         3239 g         4473 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa ataatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aggtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacttattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagctat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagatacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag agaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atatttataa tattatagaa aaatctgagg aggtgcgctc aaaatggcta
     1261 aaaaagttat aggtcaaata aaattacaaa tacctgcagg aaaggctact ccagcgccac
     1321 cagttggacc agcattagga caacatggtg ttaatataat gggattcaca aaagaattta
     1381 atgcaaaaac tgcagatcaa gctggaatga taataccagt tgttataact gtatatcaag
     1441 atagatcatt cagttttata acaaaaactc caccagctgc agttttaatt aaaaaagcat
     1501 taaacttaaa atcaggttct ggagaaccaa acaagaaaaa agttgctaaa atgacttcag
     1561 ctcaagtaag agaaatagct gaattaaaga tgcctgactt aaatgctgca tcagtagaag
     1621 ctgctatgag tatgatagct ggtactgcta gaagcatggg tgttgtaatc gaagactaat
     1681 taaaagatac actttttttt ataaagtggg aggcgagaag ccgaaattaa ccacaaggag
     1741 gaaaataaaa tggctaaaaa aggtaaaaga tatgcaggtg cattacaaaa agtagataga
     1801 actaaatttt atgatgcatc agaagcatta acattagttt cagatatagc tggagctaaa
     1861 tttgatgaga cagtagaagc acacattaaa ttaggtgttg actcaagaca tgctgaccaa
     1921 caagtaagag gtgcagttgt attacctcat ggaactggta aaactaaaag agttttagtt
     1981 tttgctaaag gtgaaaaagc taaagaagct gaacaagctg gtgctgactt tgtaggagct
     2041 gaagaattag ttcaaaaaat acaaggtgaa aactggtttg actttgatat agtagttgct
     2101 actccagaca tgatgggtgt agtaggtaga ttaggtagag tattaggacc taaaggttta
     2161 atgccaaacc ctaaatcagg aacagttaca tttgatgtag ctaaagctat agatgaaata
     2221 aaagctggta aagttgaata cagattagac aaaactaaca taatacacgt tccagtagga
     2281 aaagtatcat ttggtggaga aaaattaact gaaaacttta ctgcattaat ggatgctata
     2341 ataaaagcta aaccagctgc tgctaaaggg caatatttaa gaagtataac agtagcttct
     2401 tcaatgggac ctggagttaa aataaaccca gcaagaacag ctgaataata aaactgttga
     2461 cacaggttga caaaaatgtt atcatatcac ttgtcaatgt aaaaaagaat agatttgccg
     2521 tagatagtgg gtgcgaaagc ttaatatccc gccgaggttt tagataaatt gagattacta
     2581 aagcttttga tgtctacttt tggcaacaaa agctttttat aatgttgcgg taaatactaa
     2641 gcctatttgg tgaaggaggt gcacatctat atgagaaaag ctatagaaat taaatcagaa
     2701 gttgtttctg agatagttga aaagttacaa aaatcttctg ctgctgttgt tgtagattac
     2761 aaaggattaa cagttgaaga agtaactgag ttaagaaaac aaatgagaga agctggtgta
     2821 gattacaaag tatataaaaa tactttagtt agaagagcag ctaaagaagt tggtatagag
     2881 caatttaatg atgaattatt agttggaact aatgccatag catttggata tgatgatcca
     2941 gttgctccag ctagaatatt aaaaggattc atggattctc atccaaaaat gaaattaaag
     3001 atgggtattg tggaaggtgc attttatgat gagtctaaga ttgttgaaat ggctaacata
     3061 ccatcaagag aagttcttat cgctaaatta cttggtagct taaaagctcc agtatcaaac
     3121 ttcgcatact taatagatgc aatagcgaaa aaggcagaag gtcaagaaga agcttaattg
     3181 cttaactaaa aaattataaa tattaatttg aaataaaatt cggaggtgct aaaaatgaca
     3241 atagaacaaa tattagaagc tatagaaaat atgaaagttt tagaattaaa tgaattagtt
     3301 aaagctgctg aagaaaaatt cggtgtatca gcttcagctc cagtaatggt agctggtgca
     3361 gctgctggtg gaccagctgc tgaagaaaaa actgagtttg atgtagtatt aactgacgtt
     3421 ggttcttcaa aagttggagt tataaaagca gttagagaaa taacaggatt aggattaaaa
     3481 gaagctaaag aagtagttga caatgctcct aagacagtta aagaaggagc ttctaaagaa
     3541 gaagctgatc aaataaaaga aaaattagaa gctgctggag ctaaagtaga agttaagtag
     3601 tttctttaaa aagataccca ttgggtatct tttttattta taaaaaatta taaaggaagt
     3661 atttttataa aataaaaaaa aattatataa tagtactaaa ttaagggtat catatatgat
     3721 gtaatggtat tttaatttaa tattattata aaattaaaat ataaacaatt gttgtaatgt
     3781 atatatataa agtatataat taaattgaaa tgtaaaaaat tacatattat tttaaaaaaa
     3841 tacacgatag ttttataaat aaaatgtaat aaataattaa ttaacaaata tgaattttaa
     3901 aataagttaa acatttagaa aaatcgaaat ttgcaggatt taaagacata tttaaggagg
     3961 agttaataat ggaaaaatta caaggaaaaa ttgcagtagt tactgcggca acaaaaggta
     4021 ttggattagc atcagcagag atattagcaa aaaatggagc aactgtgtat ttagcagctc
     4081 gttcagaaga attagctaat gaagttataa ataaaataag tgcagaaggt ggctgtgcta
     4141 aatttgtcta ctttaatgca cgtgaagaag aaacttttac ctcaatgata gaagaggtag
     4201 ttaaaaaaga agacaagata gatatacttg taaataactt tggttcaaca aacccttctc
     4261 ttgatagaga ccttttgact ggtgatacag ataatttttt tgatacagta aatactaatt
     4321 taaagagtgt atatttacca tgtaaagcag caattcctca catgataaag aacgggaagg
     4381 gaagcatagt aaatatatcc agtataggct cagttttgcc tgatttatct agaatagctt
     4441 actgtgtatc aaaagcagca atcaattcat taactcaaaa tatagctaca caatatgcca
     4501 aagataatgt tagatgtaat gctgtacttc caggtcttat tgcaactaag gctgcattag
     4561 ataatatgtc tccagcattc ataaaagaat ttttaaaaca tgttccttta aatcgtatag
     4621 gagaaccaga tgatatagca aaagcagttt tattctatgc tagtgatgat tcatcattta
     4681 taacaggaga tttgcttgag gttgcaggtg gatttggttt acctactcca caatttgcag
     4741 ataatatatt aggataatta aattactaat atgtaatgaa ggctttatgt attagttata
     4801 gtatataagg atatttttat aaagaccata gatataattt atattggaaa agtttgcggt
     4861 tcaaaattcc aagttaaatt tatttatggt ttttattttg catattctaa taaattgtat
     4921 atatttgtat aaatgtaatt atttacaatc attttaatat agaattataa ttaaataggg
     4981 gggatggtat ttgtataaaa ttttatatag aaaattagtc ctataaatga aaaatatgga
     5041 ttttatattg ggaaattgta cataatacat aatatatgct taaaataatt tacaaaaaat
     5101 caaaaataat gcatagttta catataagat aaaaaatata ttgaaaaata cttgacatta
     5161 tgctaaaatt attagatgcg ttagaatgaa ctattgtttt atttttaatt attgagaggt
     5221 gaaaagtgaa tgccacatcc tgtcacgata ggtaaaagaa ctagaatgag cttttctaaa
     5281 attaaggaaa tagctgatgt gccaaatctt atagaaatcc aagtagattc ctatgagtgg
     5341 tttttaaaag aaggtttaaa agaagtgttt gatgatattt caccaataga agattatact
     5401 ggtaatctta tattggaatt tgtcgactat tctctagatg ataaaccaaa gtacgatata
     5461 gaagagtgta aagagagaga tgctacatat tgtgcacctc taaaggttaa ggtaagactt
     5521 ataaataaag aaacaggtga gataaaagaa caagaagtat ttatgggtga cttcccttta
     5581 atgacagaaa gaggaacttt cgttataaat ggagcagaaa gagttatagt aagtcaatta
     5641 gttagatctc ctggtgttta ctatgcggaa gaaagagata aaacaggtaa gagattgatt
     5701 tcatctactg taattcctaa tagaggagca tggttagaat atgaaacaga ttctaatgat
     5761 gtaatatctg taagagttga tagaacaaga aaacaaccag ttacagtttt acttagagct
     5821 ttaggaatag gaacggatgc agagataatt gaccttttag gagaagatga gagattatct
     5881 gctacattag aaaaagataa tactaagaca gtagaagaag gtcttgtaga gatatacaaa
     5941 aaattaagac caggtgaacc tcctactgta gaaagtgcat catctttact aaatgcttta
     6001 ttctttgacc caaaaagata tgacctagca aaagttggta gatataaatt caataagaaa
     6061 cttgctttat gttatagaat aatgaataaa atttcagcag aagacataat aaatccagaa
     6121 actggtgaag tatttgtaaa agctggagaa aaaataagct atgatttggc taaagccata
     6181 caaaatgcag gtataaatgt agtaaatcta ctaatggatg atgataagaa agttagagtt
     6241 ataggaaata attttgtgga tattaagtct cacattgatt ttgacataga tgatttaaac
     6301 ataaaagaaa aagtacatta tccaacttta aaagaaatat tagatggata tagtgatgaa
     6361 gaagaaataa aagaggctat aaaatcaaga attaaagaac ttataccaaa acatatatta
     6421 ttagacgata taatagcttc aataagttat gagttcaata tattctacaa tataggaaat
     6481 attgatgata tagatcacct aggaaacaga agaataagat ctgtaggtga attgttacaa
     6541 aatcaagtta gaattggtct ttcaagaatg gaaagagtta taaaagaaag aatgacagtt
     6601 caagatatgg aagctataac gcctcaagcg ttagttaaca taagaccagt ttcagctgca
     6661 ataaaagaat tttttggtag ttctcagtta tctcagttca tggatcaaac aaatcctcta
     6721 tctgagttaa cacataagag aagactatca gcccttggac ctgggggtct ttcaagagaa
     6781 agagctggat ttgaagtgcg tgacgttcac cattcacact atggtagaat gtgtccaata
     6841 gagactccag aaggaccaaa tatcggtctt ataaactctc taggaactta tgcaaagata
     6901 aatgaatttg gatttataga atcaccatat agaaaatttg ataaagaaac atcaacagtt
     6961 actgatgaaa tacattattt aactgctgac gaagaagatt tattcgtaag agctcaggca
     7021 aatgagccat taacagaaga tggtaaattc gtaaaccata gagttgtttg tagaactgta
     7081 aatggtgctg ttgaaatggt tcctgaaagt agagtagatt acatggatat atctcctaag
     7141 caagttgtat cagttgccac tgctatgata cctttcttag aaaatgatga tgctaaccgt
     7201 gcccttatgg gagcaaacat gcaacgtcag gcagtacctc tagttagaag agaagcacca
     7261 attataggaa ctggtataga atacagagca gcaaaagatt ctggagcagt tgttgttgct
     7321 agaaactctg gtatagcaga aagagtaaca gcagatgaaa taattataaa aagagaagat
     7381 ggaaatagag atagatataa tctacttaag tttaaacgtt caaactcagg tacttgtata
     7441 aatcaaacac ctataataaa taagggtgac cagataatga agggtgatgt tatagcagat
     7501 ggtccagcaa cagacttagg agaagttgca cttggaagaa actgccttat agcattcatg
     7561 acttgggaag gttataacta cgaggatgct atattaataa atgaaagatt agttaaagaa
     7621 gacagattat caacaattca tatagaagaa tatgaatgtg aagctagaga tacaaaacta
     7681 ggaccagagg aaataactag agatatacct aatgttggag atagtgcaat taagaactta
     7741 gatgacagag gtataataag aataggtgca gaagtagatt caggtgatat actagttggt
     7801 aaagtaactc caaaaggaga gactgaactt actgctgagg aaagattact tcgtgcaata
     7861 tttggagaaa aggctagaga agttagagat acttcactta aagtacctca tggtgaatct
     7921 ggtataatag tcgatgtaaa agtgtttact agagaaaatg gagatgattt atctccagga
     7981 gtaaatgaat tagtaagatg ttatatagct aaaaagagaa aaataaaagt tggagataaa
     8041 atggctggtc gtcatggtaa taaaggggtt atctcaagag tgttacctga agaagatatg
     8101 ccattcatgg aaaatggaac accactagat ataatactta acccacaagg tataccatca
     8161 cgtatgaaca ttggtcaggt tctagaagtc catttaggac ttgctgctaa aacattagga
     8221 tggtatgtag caacatcagt attcgatggt gctaatgagt atgatataat ggatgctctt
     8281 gaagaagctg ggtatcctag agatggtaaa ttaactttat atgatggtag aacaggtgag
     8341 tcttttgaca atagaataac tgttggatat atgtattact tgaaactaca tcacttggta
     8401 gatgaaaaac tacatgcaag aagtactgga ccatactcat tagttactca acagccacta
     8461 ggcggtaaag cacaatttgg tggacaaaga tttggagaga tggaggtttg ggctctagaa
     8521 gcatatgggg ctgctcacat acttcaagaa atacttactg ttaagtctga tgacgttgta
     8581 ggtcgtgtta gaacatatga agctatagtt aaaggtgaaa atatacctga accaggaatc
     8641 ccagaatcat ttaaggttct tataaaagaa cttcaaagtt tatgcttaga tgtaaaagta
     8701 ttgacagatg aagaccaaga aatagaagta agagaatctg tggatgaaga tgatacaata
     8761 ggtgaatttg agctagatgt tgtaaatcat atgggagaag ttgaagaaag taatataata
     8821 gaagaaattg aagatgattt tgcagaaaac gcagaagatg aggatataga gaatttagaa
     8881 gaattcactg aagatgattt atttgaagaa gaaatagatt ttgatagtga tgactttgat
     8941 atgtaaattt aattaatgta aatctcaaat agaagggaga gaactccttg tttgaattaa
     9001 acaatttcga gtcgataaaa atagcattgg cttctccaga aaaaataaga caatggtcta
     9061 ggggagaagt taaaaagcca gaaactataa attaccgtac tttaaaacca gaaaaagatg
     9121 gtcttttctg tgaaagaata tttggaccac aaaaagactg ggagtgccac tgtggtaaat
     9181 atagaagagt tagatataaa ggtgtagttt gtgatagatg tggagtagaa gtaactaaat
     9241 caaaagtaag aagagagaga atgggacata tagagctagc cgctcctatg tctcacatct
     9301 ggtacttcaa aggtatacca agtagaatgg gacttttact tgacatgtca ccaagatcat
     9361 tggaaaaaat attatacttt gcatcatatg tagtagttga tccaggagaa actggattaa
     9421 acgaaaaaca attgcttaca gaaaaagaat acagaactgc tcttgaaaag tatggatata
     9481 cttttactgt aggaatgggt gcagaagctg taaagacgtt actacaaaat atagatttag
     9541 aacaacaaag taaagaccta agagcggagt taaaagatag tacagggcaa aagaaagtta
     9601 gaacaataag aagattagaa gttgtagaag catttaaaaa gtctggaaat aaaccagaat
     9661 ggatgatttt agatgcgata ccagtaatac caccagattt aagaccaatg gtacaacttg
     9721 atggtggaag atttgcaact tcagacctaa atgatttata tagaagagtt ataaatagaa
     9781 acaatagact taaaagatta ttagagcttg gagctccaga tataattgta agaaatgaaa
     9841 aaagaatgct tcaagaagct gttgatgcac taatagataa tggtagaaga ggtagacctg
     9901 taacaggacc tggaaataga ccacttaaat ctttatcaga tatgttaaaa ggtaaacaag
     9961 gtcgtttccg tcaaaactta cttggtaagc gtgttgacta ttcaggacgt tctgttatag
    10021 ttgttggacc agagcttaag ttctatcaat gtggacttcc aaagaagatg gcattagagc
    10081 tattcaagcc atttgttatg gataaattag ttaaagaagg atatgcacat aatataaaaa
    10141 gtgccaaatc tatagtagaa aaagttaagc cagaagtttg ggatgtttta gaagatgtta
    10201 taaaaagcca tccagttctt cttaaccgtg cgccgactct gcatagatta ggtatacaag
    10261 catttgaacc tatcttagtt gaaggtaaag ctataaagct acatcctctt gtatgtacag
    10321 cttacaacgc agactttgat ggtgaccaaa tggcagtcca tgtaccttta tcagtagaag
    10381 cgcaagcaga agcaagattc ttaatgcttt ctgtaaataa tatacttgct cctaaagatg
    10441 gttcacctat aactactcca tctcaggata tggttttagg ctgttattat ctaacaatag
    10501 aagcacaaga cggagctaag ggaacaggta tggtatttaa agactttaat gaactattac
    10561 ttgcttatta caataagtca gttcatctac atgcattagt aaaactgaag gtaacacttg
    10621 aagatggaag aagttcatta gttgaaagta ctgttggaag atttatattt aatgaaaaaa
    10681 tacctcaaga cttaggtttt gtagatagaa aagaaaaccc atttgctctt gaagttgatt
    10741 tcttagcaga taaaaagtct cttggtaaaa taatagataa atgctttaga aaacatggta
    10801 atacagagac agctgaattg ctagattata taaaatcttt aggatttaaa tactctacat
    10861 taggtggtat aacagttgca gtagatgata tgagtgttcc agaagaaaag aaagtattta
    10921 tagctgaggc agaagctaaa gttgataaat atgaaaaagc atacagaaga ggtctaatat
    10981 ctgatgaaga aagatatgaa aaagttatag agacatggac agaaacaact gataaagtta
    11041 ctgacgctct tatgggtgga ctagatagac taaataatat atatataatg gcacattcag
    11101 gagccagagg ttctaaaaac caaattagac agctagcagg tatgcgtggt cttatggcga
    11161 atgcatctgg taaaacagtt gagataccag ttaaatctaa tttccgtgaa ggtttatcag
    11221 tattagaata ctttacatct tcacatggtg ccagaaaagg tcttgcagat acagctatac
    11281 gtacagctga atctggatac ttaacaagaa gacttgttga tgtaagtcaa gatgttattg
    11341 taagagaagt agattgtgga acagaagata ctacagaaat ttatgctata aaagaaggaa
    11401 atgaagttat agaagaaata tatgatagaa ttgtaggaag atatactata gaccctatat
    11461 taaatccgga aactggagaa gttatagttg aggctgattc aatgatacaa gaagatgaag
    11521 cagaaactat agtagcttta ggcattgaaa aaattaggat aagaacagtt cttaactgta
    11581 aaactaatca tggagtttgt tctaagtgtt atggtagaaa cttggctaca ggaaaagaag
    11641 ttaatatagg tgaagcagtt ggtataatag cagctcaatc tatcggtgaa ccgggtactc
    11701 agcttacaat gcgtacattc catactggag gagttgcagg agctgacata actcaaggtc
    11761 ttccaagggt tgaagaatta tttgaagcta gaaaaccaaa aggattagct gtaataactg
    11821 aagtatctgg tagagttgaa attgatgaaa caggaaagag aaaagaagta aatgtaatac
    11881 cagaagaagg cgagactcaa acatatgtaa ttccatatgg ttctagatta aaagttaagc
    11941 aaggtcaaat gctagaggct ggagaccctc taacacaagg atttataaat cctcatgata
    12001 tcgtaagagt aaatggtgtt aagggagttc aagaatatat agttaaagaa gttcaaagag
    12061 tgtatagact tcaaggggtt gatgttaatg ataagcatat agaagttata gtaagacaaa
    12121 tgctatctaa agtaaaagtt gaagacccag gagatacaga tttattgcca ggtggatatg
    12181 aagatgtatt aacattcaat gaatgtaata aagatgctat agataaaggt ctaagaccag
    12241 cagttgctaa aagagtttta cttggtataa ctaaagcatc tcttgcaact gattcattct
    12301 tatcagcagc ttctttccaa gaaacaacaa gagtattaac agaggcagca ataaaaggta
    12361 aagaagacca cttaatagga cttaaagaaa atgttatatt aggtaagtta ataccagcag
    12421 gaacaggaat gaagaaatat agaaatatag ctgttgaaaa aattgaagat taatagcata
    12481 tagagtaaag aaatcttgac aaccattatt tgtggtgtta aaatagtaaa gtgtgttgtt
    12541 taaaagtaca ctaagggctt gaacaagctc ttagtgactt ttagatggca ataaataaga
    12601 actaaaaagc atcaagctag aaaagtgcta atatcacata tttatgtgtt atagacatta
    12661 aattgtaagt aacgaatgtt acaatcagtc agtatgaata attcatattg atgtagttgg
    12721 cggtcactga taagatcgaa aatttggaag gaggtgcaga tgatgccaac aattaaccaa
    12781 ttagttcgta aaagtagaaa agcgctagag aagaaatcta ctgctccagc attacaaaaa
    12841 ggttacaact ctttaaataa gaaagtaact gacgctagtg ccccacaaaa aagaggggtt
    12901 tgtacttcag taaaaacagt tactcctaag aagcctaact cagctttaag aaaagttgcc
    12961 agagttagat taactaatgg tatagaagtt tctgcttata taccaggaga aggacacaac
    13021 ttacaagagc atagtgttgt tcttataaga ggaggaagag taaaagacct tccaggggtt
    13081 agataccata tactaagagg tactctagat acagcaggtg ttgataagag aagacaatca
    13141 agatctaaat acggtgcgaa gagacctaaa gaagctaaaa aataaaacaa ttaatgattg
    13201 attatagttc ggtgctttaa atatatatat atttacggca tcacggcatt aaatgattta
    13261 tgtcgagtac ctatgattta agttaaataa ttaaggaggg aagcgaaatg ccaagaaaag
    13321 gtaatattcc aaaaagagaa gttttaccag atcctatgta tgggagtaag gtagttacta
    13381 aattaataaa taatctaatg gtagacggaa aaaaaggaaa gtctcaaaga atagtttatg
    13441 atgctttcgc aattgttgct gaaaagacag gagaagaagc tttagaagta tttaataaag
    13501 caatggataa tataatgcct gttttagaag taaaagcaag aagagttggt ggagcaaact
    13561 accaagtgcc aatcgaagtt agacctgaaa gaagacaaac attaggttta agatggctag
    13621 taaaatatac tagagctcgt ggtgaaaaag gaatggttga aaagctagct aaagagataa
    13681 tggatgcagc taacaacact ggagcttcag ttaagaaaaa agaagatact cataaaatgg
    13741 cagaagctaa taaagcattt gctcattaca gatggtagga tatatagata tcttataaat
    13801 tcaaggatat cataaggagg ataaccatgg ctagaaagtt tcctttggaa aaaactagga
    13861 atataggaat catggctcat atagatgcag gaaagactac tactacagaa agaatcctgt
    13921 tttatactgg gcaaactcat aaaataggag aaactcatga aggagcttct caaatggact
    13981 ggatggagca agaaaaggaa agaggtataa caataacttc tgccgctact actgcttcat
    14041 ggaaagacca tagaataaac ataatagata ctcctggaca cgtggacttc acagttgagg
    14101 ttgaaagatc tctaagagtt cttgatggtt cagttgctgt attctgtgca aaaggtgggg
    14161 ttgagcctca atctgaaaat gtatggagac aagctgaaac ttatggagta cctagaatag
    14221 cttttataaa caaaatggat atattaggtg cagatttcta caatgttgta agcatgatga
    14281 aatctagatt aaattctaat gcagttccta tgcaattacc aataggtaaa gaagattcat
    14341 ttataggtat aatagactta ttaaaaatgg atgctgttat atacaaagac gacttagggg
    14401 ttgaaatgga agaaacagac ataccagaag atatgaaaga attagctgct gagtggagag
    14461 aaaaattagt tgagtcagta gctgaaactg atgaagaatt aatgatgaaa taccttgaag
    14521 gtgaagaact tactatagat gaattaaaag ttgctataag aaaagctact atagcttgtg
    14581 aaatgaaccc agttttctgt ggtacagctt atagaaacaa aggtgttcag ttagtaatag
    14641 atgcagtttt agattactta ccagcaccaa ctgatatacc agctataaaa ggtatattag
    14701 cagatggaga agaagctgaa agacattctt ctgatgaaga gccattctct gcattagcat
    14761 tcaaaataat gactgaccca ttcgttggaa aactagcgtt cttcagagtt tattctggaa
    14821 cattagaatc tggttcttat gttttaaatg caactaagaa taagagagaa agaattggtc
    14881 gtatattaca aatgcatgcc aatacaagag aagaaataac taaagtttat gctggagata
    14941 tagcagcagc ggtaggatta aaagatacta ctactggaga cacattatgt gaccctgcta
    15001 atccaataat acttgaatct atggaattcc ctgagccagt tatatctgtt gctatagagc
    15061 caagctctaa agcagcacaa gagaaaatgg gtatagctct tcaaaaacta gctgaagaag
    15121 acccaacttt cacagttaag actgaccaag aaacaggaca aactataata tctggtatgg
    15181 gtgaattaca cttagagata atagtagata gattattaag agaatttaaa gtagaagcta
    15241 aagttggtgc accacaagtt gcatatagag agactataac tcaaccagtt gatgttgaat
    15301 acaagtactc taagcaatca ggtggtagag gacaatacgg tcacgttaag attagagttg
    15361 ctcctcaaga gccaggtgaa ggatacaagt tcacaaacaa aactgttggt ggatctgtac
    15421 caaaagaata tgttggtcca gttgacatgg gtatacaagg agctatgcaa tctggtatag
    15481 ttgctggata tccagttgta gacgttgctg ttgagttata tgatggttct taccatgagg
    15541 ttgactcttc tgagatggcg ttcaagatgg ctggttcaat ggcattcaaa gatgctatga
    15601 agaaaggtaa tgcagttctt ttagagcctt acttcaaagt agaagttgtt actccagaag
    15661 attacatggg agatgttatg ggtgacttaa actcaagaag aggattaatc caaggtatgg
    15721 aagctagaag tggtgcacaa gttataaatg cattcgttcc actttcagaa atgtttggat
    15781 actcaacaga cctaagatct tcaactcaag gtcgtgcaac ttacacaatg atattcgatc
    15841 actatgagca agttccagct tcagttgcta agaaaatagc tgaaggaaaa taatttaaaa
    15901 ataattaata atataaatat aaaaaataat cagctagatg agatatatct catctagcac
    15961 aagat
//
LOCUS       DAMKOJ010000079        15831 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000079 DAMKOJ010000000
VERSION     DAMKOJ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15831
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.085"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..2558)
                     /gene="carB"
                     /locus_tag="PC592_002830"
     CDS             complement(<1..2558)
                     /gene="carB"
                     /locus_tag="PC592_002830"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF4056778.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIAENEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVAKELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGV"
     gene            complement(2611..3654)
                     /gene="carA"
                     /locus_tag="PC592_002831"
     CDS             complement(2611..3654)
                     /gene="carA"
                     /locus_tag="PC592_002831"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF4056779.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKETIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     TENIKGTGAKVTVIDFGVKNSVLESLKACNCDITIVPAMTTAEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(3680..4396)
                     /gene="pyrF"
                     /locus_tag="PC592_002832"
     CDS             complement(3680..4396)
                     /gene="pyrF"
                     /locus_tag="PC592_002832"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDF4056780.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDKLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     VAKEEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKRGAHYLVVGRPI
                     TKAKDPRESAINIVREIENA"
     gene            complement(4772..5407)
                     /locus_tag="PC592_002833"
     CDS             complement(4772..5407)
                     /locus_tag="PC592_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HDF4056781.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     KKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKVFEHH
                     GFEVFSVICKNGAIPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEARVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(5431..6345)
                     /locus_tag="PC592_002834"
     CDS             complement(5431..6345)
                     /locus_tag="PC592_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056782.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKSFEEDEEDDLDYLVGIKTEEEDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKKPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEEIQEENVSLEKEELQDE"
     gene            6947..8176
                     /locus_tag="PC592_002835"
     CDS             6947..8176
                     /locus_tag="PC592_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF4056783.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLSDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNKNLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPEGHVWLSGASKDPNGVSFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDKYGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGDWAF"
     gene            complement(8381..10762)
                     /locus_tag="PC592_002836"
     CDS             complement(8381..10762)
                     /locus_tag="PC592_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HDF4056784.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGIQNPEKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSEYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVESPTVVGERLNPTGRKALQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLKSILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVDRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAIAMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNECSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKLDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDKI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(10734..11459)
                     /locus_tag="PC592_002837"
     CDS             complement(10734..11459)
                     /locus_tag="PC592_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HDF4056785.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKDTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNIVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSDLTKGLIIDSCGTTAIEEVCDIVQDNVEKVFLKQNKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISDTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(11449..11904)
                     /locus_tag="PC592_002838"
     CDS             complement(11449..11904)
                     /locus_tag="PC592_002838"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDF4056786.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(12186..13367)
                     /locus_tag="PC592_002839"
     CDS             complement(12186..13367)
                     /locus_tag="PC592_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF4056787.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLIVTSMYIIKSLYFNGAI
                     SVINQLVYQLRDFRSLIGESLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDNEKDDIDELAYKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVISQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGLYVDIVTEKKGDIAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHGGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(13357..14049)
                     /locus_tag="PC592_002840"
     CDS             complement(13357..14049)
                     /locus_tag="PC592_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056788.1"
                     /translation="MKNTILVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMVLDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIEVGAVIIDKEKHSVTVAGNDIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(14183..14899)
                     /locus_tag="PC592_002841"
     CDS             complement(14183..14899)
                     /locus_tag="PC592_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF4056789.1"
                     /translation="MKKFKLIVAIILVVFISVFISKDRLLKKDKEPTVIAQHYSKQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            15025..15759
                     /locus_tag="PC592_002842"
     CDS             15025..15759
                     /locus_tag="PC592_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis protein TtcA"
                     /protein_id="HDF4056790.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRKEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
BASE COUNT         4850 a         2858 c         1755 g         6368 t
ORIGIN      
        1 actccactta ctttgcttat atatggaact gttctactag ctctaggatt aacttcaatt
       61 atatataatt cattttgaaa ttctataaac tgtatattaa ccataccaag cacattaagg
      121 tctaaagcta tttttttagt atattctact attttttctt ttatttcatc agatatattt
      181 tgacttggat acattgttgt actatctcca gagtgaactc cagctctttc taaatgctcc
      241 attataccag gtattaatat atcttcctta tcacatatag cgtctacttc tatttctcta
      301 ccagttagat atttatctat aagtactgga ttcttatggt ctctatcaaa tgcatcttgt
      361 aggtattgag ataatttttc ttcgttataa gttatttcca taccttgacc accaagtaca
      421 taagatggtc taactaatac tggataacct aattccttag caacttcaat accttcgtta
      481 agtgaccata caccttttcc ttttggtcta tttatatcta gtctctctag taaatcatca
      541 aacttctctc tatcctctgc tgcatctata tcatcaaaat ctgttcccag tataggtata
      601 tttttttcat gtaagaactt agccaatttt atagctgtct gtccaccaaa ctgtagtatt
      661 acaccttctg gtttttcttt ttctattata cttaaaactt cttcttctgt taatggttca
      721 aaatataact tatctgatgt atcaaaatct gtacttacag tttcagggtt attgtttatg
      781 attatggttt ctatgtccat ttttcttaaa gattttacac aatgaactga acaataatca
      841 aattctatac cttgacctat tcttattgga ccagagccta gtactatcac ctttttctta
      901 tcactaacaa ctacctcatc atattgctca taagttgaat aatagtaagg tgatatagcg
      961 tctatctcac ctgcacatgt atcaaccatt ttatatgctg gcttgatatt gtatagactt
     1021 ctcaattcat ataatttttc tgggcttatc ttcattaagt cagatatacc tttatccgag
     1081 aatccctttt tctttaattc aagaagatag tctttagtta aatcttcaat tttcataact
     1141 tttaattttt cttcttgctc tactatccat ttgaatttat ttataaacca tttatctata
     1201 cctgtaattt gttctatcat ttctacttta tagcctcttc ttatcatttc agctaagtca
     1261 aataatctct catcatcagg cactacaact cttttcttta attcctcaat acttctctcc
     1321 tcagatggtg tgtgaaccaa tgaatatttt cctgtttcaa gtgaccttat ccctttaaga
     1381 atagcagcct caaagttact tcctatactc atgatttcac cagttgccat catcttagtg
     1441 cctaattttc tatttgcttt tttaaattta tcaaaaggcc attttggtat ttttgctacc
     1501 acataatcta tagttggttc aaaacaagca taagtttttt tagttactgc attttctatc
     1561 tcatctaaag tataacctaa agctattttt gacgaaactt tagctattgg atatcctgta
     1621 gcttttgatg ctaaagctga tgatctactt actcttggat ttatctctat aactgcatat
     1681 tcaaaactat gtgggttaag tgcaaattga acgttacatc caccttgaac ttctactgca
     1741 tttaatatat ctaaagatgc ttttttaagc attgcacatt ctttgttact taaagtttga
     1801 gttggagcaa caactatact atctcctgta tgaactccga ctgggtctat gttttccata
     1861 ttacatacaa ctatacaatt tccctttgaa tctcttatta cctcatattc tatttccttc
     1921 cagcctttta tactcttttc tattaatact tgtccaacag ggcttaattg tagtccatgt
     1981 gaaagtattt ctcttaattc ttcctcattt tcagctatac ctccaccagt tccacctagt
     2041 gtgtatgctg gtcttacaac tactggataa ccaattgtaa gtgcatagtc aagacctgct
     2101 tgtaaatctg taactatatc actaactatt acaggctgat ttatttcttt cattacttct
     2161 ctaaatatat ctctatcttc accttttttt atagattcta ctgaagtacc tattattttt
     2221 actccatatt tgtctagtat acctttttca taaagttcaa ctgctaagtt taatcctgtc
     2281 tgaccaccca tacctgcaag taaactatct ggtctttctt tttctattat tttttctata
     2341 aattctattg ttaatggttc tatatatatt ttatctgcaa tctctttatc agtcattata
     2401 gtagctggat tactatttat taatacaact tcaattcctt cctctttcaa agattggcaa
     2461 gcttgtgttc ctgaatagtc aaactctgca gcttgaccta ttattattgg tcctgaccct
     2521 aatactaaag ttttctttat actatctaat ttaggcataa atttttctcc ttatctaaat
     2581 ggtttttact atctgaaaat aatactaaat ctatattaat gctaagaatt tattaaatat
     2641 acaatctaaa tcttcttttg ttgtgtattc tggaatgtac tgaacactat atattggtaa
     2701 ttccttatgt ctcattcctt ctatagtatt gtcatttaaa tttatgtgag ttacctctgt
     2761 attttctggc atttctgaaa cattatatcc atggttttga gaagttataa atacctttcc
     2821 agtttctaaa catttaactg ggtgattgcc tcctctatgt ccaaatacaa gttttgaagt
     2881 ctttcctcct aatgccagtg ctaaaatttg atgtcctaaa cctattcctg tcaatggctt
     2941 tttgcctatt aattttttta tattttcaac tatatcattt atatcctctg gatttcctgg
     3001 tccattagat aataaaatta agtcaggatt tatatttaaa atttcttctg ctgtagtcat
     3061 tgctggtact atagttatat cacagttaca agctttaaga gactctagta cactattttt
     3121 aacaccaaag tctataactg taaccttagc accagtacct tttatatttt cagtttcttt
     3181 tcttgtaaca ttttttactg aatctttgtt acaatgctct tctaacttag actgaacatc
     3241 ttgtaatgat acattttcta aagttataat tcctctctta gttccattgt ttctaataat
     3301 tttagttaat gctcttgtat ctattccttc aagtcctatt accttatttt gctttagata
     3361 tgtgtctata tccatttcac atctaaaatt atttgggtta tcacttttct ctcttacaat
     3421 aagtcctttt acttgcacct tatttgattc aacatcttct aaatttattc catagtttcc
     3481 tataagtgga taagtcatag taactatttg tccataataa gttgcatctg tcaatagttc
     3541 tccatatcca gccattgaag tattaaatac aacttctcca atagtttcct ttagatatcc
     3601 aaatgctttt ccttcaaata ctgttccatc ttctaaaatt aatttcccct tcatataagc
     3661 tacctcccaa atattttatc taagcatttt ctatttctct tacaatatta atagctgatt
     3721 ctcttggatc ttttgctttt gttataggtc ttccaacaac taaataatga gcacctcttt
     3781 ttattgcatc tgatggagtc acaactcttt tttggtcccc aacctctgct gatttaggtc
     3841 ttattcctgg gcaaactgtt ataaaatcag ttccacatgc ttctactatt ttatctactt
     3901 cttgcgctga acaaacaacc ccatctattc ctgattcttt tgccagttta gctctcttta
     3961 tagctagctc ttctgtcgtc atattacatc ctatgtcctg taaatcttgg ttgcttaatg
     4021 aagttagaac tgttactcca actactaatg gcttttctat atttaatctt tctgcttctt
     4081 ctttagcaac tagtgcacat tgtctcattc cttccatgtc tgatacatgt attgtcatta
     4141 accaaacatt atctctgact gcagctctca ctgcactttt catagtattt ggtatatcgt
     4201 ggaatttaag gtctaaaaat atttttttgc ctttttcttt aagataatct atcgttttac
     4261 cttttgtggc aacatattgc tctaacccta ctttaaatat atctacacta tcttctaatt
     4321 tgtctattag ttctttagct ttatcaaatt cgtcagtatc aattgcaact atcaactttt
     4381 ctttaccatt tatcattttt acatctcctt tttaataaag cctaaatctt cataaaaaaa
     4441 tcctcacacc aaaagaggca caaggatttt atctatacat aactctattc attagctatg
     4501 agatatcttt cccagtctct ctggactagt ttaaaagact ttattatatt taaattttta
     4561 ttttatactc atcaaaaacc tctagaagat ttactagagg ttatatgcta acactatcta
     4621 taacccttta gtctctctgg actactttaa ggaatttagc tgtaatattt ttctttattt
     4681 atataatttt atgtatctat aagataactt aaagttttat cttttttata attaaaccac
     4741 taattgcttt ttatgtcaat aagtctttga attattcttc atctttatca aacaattttt
     4801 tctcaaaata tgattctgca ttatatattg cagcaactgg attatgccca gttactctat
     4861 ctttgacaac taaagttgtt ataggagctt ccatatattt catggctaaa gtatcatgac
     4921 caacacataa tccaagaatt acattaaggt caaccctagc ttcatttaaa aataaagctt
     4981 gtcctattgg attgcacatt acctcatctg aacattttga tattgtttga gatgcttcta
     5041 gtccaattgt actcttaggt attgccccat ttttacatat aacagaaaat acttcaaacc
     5101 catgatgttc aaatactttt tgtactgttt gcatttctct ttttagccca atacaaaatg
     5161 ctataccaat ctttttataa ccacactttt tagcaaactc tataatctct tttagtctag
     5221 tatattgaca atacccctct gcttcaacta gtccagcatt ataagctatt tttttattct
     5281 cttcttcttc ataaagttgc tttgcttttt gttgtagctc aatttctcta gttggacata
     5341 tcttcattaa tttatccata tttccattag aacagcctct aagattacat tttccacact
     5401 tatacatatc caatatcccc ttccaaaatt ttattcatct tgtaattctt ctttttctag
     5461 acttacattt tcttcttgga tttcttcttc tggtttcaca tgctcaacta cagttataaa
     5521 atatgatttt cctattttat tccttatagg aagtttttca tatgaaacat ctattttatt
     5581 ttttatacaa gctatatcaa aatgtcttaa ggctacacct aagctaacct tattcatatc
     5641 ttcacagtgt ttcttaggtt tcttttcaaa taaatgaaga cctcgttcat ctttatggaa
     5701 ataccaaggt tgagaatttt ttacagatgg agctcttctt gtcaattcta aaatatcttt
     5761 ccactttcta ttcctattta tcttatttat catatctttt actggctttc tatctggtct
     5821 agcatatcta gtcctaaaca actcttcatt ttttgctgga tatccaaatg ctattattat
     5881 ataaggattt tctattttgt tttcatcttc ttcttctgtt tttattccaa ctaaataatc
     5941 taagtcatct tcctcatctt cttcaaagct cttattccca atatctacaa attccaagat
     6001 atcttctctc tttaagtttc cttcaagcca acaggtagct attcccaatg ttgtaagacg
     6061 taaaactaca ccttctgtag caaaccctat attctgtaaa tagtcctcac ctttatctga
     6121 tgtgactact atataatgag gtgcctttac cttacattcc ttacccatca aaaaatgtat
     6181 tatatgacct ctatcaacaa catgtgcttt aatatttaaa tcttcattta agtattctaa
     6241 atttttacaa cttcttttta tttcttccat taatggcttt tttatcttct tactggaaaa
     6301 atttcttaca gattttctat aaaaaatggc ttcataaagc tccatttatg ccctcctaac
     6361 tgaactcttc tgacctataa actctataaa tttatataaa tactttatat tttttatagt
     6421 tttatttcct ttttcctcct gctctatttt gaaattcata agaatatcta ctctagttta
     6481 atatagcagt ctaaaggctt aaattctatc ttgtcaatgt ctatatatta gcacaatttt
     6541 tttatttgat tctctatgct aatttaaata acaacactag ctattacttt tataattaag
     6601 ctttgccaga aaaatttttt ttcatttata aatatctatc tcattattat attataagtt
     6661 tttttcggta ttcttgtata gcttttcact aaaaaagtat ttttatttct actttaatac
     6721 tattatcaac aaaaaacata ctgcttaaat aggtttgcta tcttcacaat ctgttttaat
     6781 taaaatatat ttttttattt ctcaatctat aaagtataaa tattttgaat atgacctaaa
     6841 atctaagtaa agttataata ttttataagt tgttcaatat taaaaacata agtaatgtta
     6901 taatacttta taagttattc aatattaaaa atataggagg ataaatatga atttaaatag
     6961 aaatttagaa aaatacgctg aattagcaat aaaagttgga gttaacatac agccaggtca
     7021 aattctactt ataaaatcac caatagaatg tgctgatttt gcaagaaatg cacttaagga
     7081 agcctataaa tgtggtgcta aaaatgtgta tatagagtgg tctgacgaag aaagcactct
     7141 tattaagtac ttatatgctc cagatgaggc atttcatgag ttcccaaagt ggacagcaga
     7201 acaatatgta gatatagcaa aagaaggtgg agcattttta tcagtctatg cccaaaatcc
     7261 agatttatta aaagatgttg accctgaaag agttgcaaat tttcaaaagg catctggaaa
     7321 agctttaaaa gaatggcgtt cttacactct aagtgataaa tgtaaatgga gtatagtctc
     7381 tgtgccaaca aaagattggg caaaaaaagt gtttccaaat ttatcagaag ataaggcaat
     7441 agaaaaattg tgggatgcta tatttaaatg ttcaagagta gatggtcaag accctataaa
     7501 agcatgggaa gaacataata aaaaccttaa atctaaaatg gactttctaa ataaaaataa
     7561 ctttaaaact ttaaaatata aatcctcaaa aactgatttg actttagact taccagaggg
     7621 tcatgtctgg ctaagtggag catccaaaga ccctaatgga gtaagtttta atccgaatat
     7681 tccaactgaa gagatttttg gaatgccaca taagtttaaa gtaaatggaa ctgtttatag
     7741 tacaaaacct cttgtttatg gtggaaacat aattgataat ttcttcttaa catttaaaga
     7801 tggaaaaata atagattttt ctgctgaaaa gggactagat acactagaaa aacttattga
     7861 aacagatgaa ggttctcatt atttaggaga agttgctctt gttccataca actcaccaat
     7921 atccaatacg gatataattt tttataatac tctatatgat gaaaatgcat cttgtcactt
     7981 tgcaattggt tctgcttata aaacttgtct agaaggtgga aacaatttaa aagatgaaga
     8041 attagataaa tatggtgtaa atgacagttt aacacatgta gattttatga ttggttctgc
     8101 tgatatggat attattggtg aaacttatga tggaaagcaa atacagattt ttaaaaatgg
     8161 tgattgggct ttttaacata tgattttaac taaaaagggc tgttggaagt tataccagac
     8221 ttcccagccc tttttaatgt tgatgataaa tattttttat attaattaat ctcattatta
     8281 tagattaatt cctattgttt taaacataag tatctaaaac ttatatttat attatatata
     8341 aaatatccta tttagtaaaa cctttatttt aatttacatg ctaaaaattt aactttgcta
     8401 tttcaacagc agactttgca tcctttgaat aataatcagc gcccatttct tcagcgtatt
     8461 cttctgttaa aactgcaccg cctacaaata cctttgcatt tatctcatta tctctcagtg
     8521 cctgaattgt atctttcata ctttgaacag ttgtagtcat aagtgcactt aatcctacta
     8581 attttatatt tcttttttta gcaacttcca ctacttcttc aatagggaca tctttaccta
     8641 aatctataac ctcatatcca taattttcta gcattatttt tactatattt ttcccaatat
     8701 cgtggatgtc tccttttact gtagcaacta ttatttttcc tttagataca ttattgctac
     8761 ttttacttaa taaagtttcc tttattgtat ttaatgaaac ttttaccgtt tctgctgatt
     8821 gaatcaattg tggtaaaaat atatctccac tatcatatct ttttcctact ttatcaagag
     8881 caggaattaa aatcttatct aatatataat tttcatcctt ctcttttaaa agattcagtg
     8941 ttacattttt tgcttcatct tttaatcccc tttcaactaa aatatccaag ggcaaatctt
     9001 tgtcaatctt tgtagatgaa tccaattttt ttgaattatt tatattacta tattgattta
     9061 tatagtttat acatccttta tctgtgttat ttaatatttt aaaagaattg atagcttcca
     9121 tcatactaca ttcatttgga tttataattg ctaaatcaag ccctgctcct aaagctaatg
     9181 ttagaaaaga agcattaagt gcttttctat tcggaagacc aaatgaaata tttgaaacac
     9241 ctaatatagt ttttactcct aatgtcttta ccattgctat ggcttttata gtttctattg
     9301 cttcttcttg ttgtgctgaa acagttaatg ataaacagtc tataaatatg tcttttggtt
     9361 ttatgccata agaaactgct ctatcaacta tcctttttgc tatttcaaat ctttcttcag
     9421 cctttttagg tatccccttt tcatcaagtg taagtccaac tacacacgaa ccatactttt
     9481 taactatcgg taatatgctt tttaaagact cttctttgcc atttacagag tttactattg
     9541 ttctaccatt ataatatcta agaccttgtt ctaaagcctc tacattggaa gaatcaactt
     9601 gtaaaggtgt atctactact gcttgaatct ctcttattaa ttttggcatt aatttttttt
     9661 catcaatctc tggaagacca acattcactc caagtatttg tgctccagca tttacttgtt
     9721 ctaagcctaa atttatagca taatcaacat tttcattttt taatgcttct tgtagagctt
     9781 ttctacctgt aggatttaat ctttctccaa caactgtagg tgattctact tcaacaaatt
     9841 ttgatggtga acaaactaca catttatcaa ttttctcgat acatcccttt gtaacagaat
     9901 ttatattctc agatatttct tttataaaac ttggattcgt accacaacat ccgcctatta
     9961 tagtagcacc aacctcaacg aactttttaa ccccttcaaa aaattctttt gcatcaacat
    10021 catatatagc ctctccatca actatatttg gaagacctgc atttgcttga accataacag
    10081 gtactgtagc tcttgatgct attttttcaa ctattggtaa aagttgttta ggtcctaatg
    10141 aacaattaac tcctattgca tctacaccta acccttctat agtagccacc atacattctg
    10201 gcatacatcc agtaaaactt cttccacctt catcaaatgt catagtacag aaaataggta
    10261 aatcagaatt ttcttttgct gctaatacag ctactttagc ttcatataaa tccatcatag
    10321 tctctattac tatcacatct actccagatt taacgccttg cagtacttgc cttttaaata
    10381 tttcatatgc cttatcaaaa cttaaagtac ccataggctc tagcatctct cctataggac
    10441 caatatctaa agctacatat cttggtttag tattatctac attttctata gctttcctag
    10501 ccaccaaaac agcattatca atcacttctt ctacagtata ctcactatct aattttagtt
    10561 cattacatcc aaaagtattt gtaagaatta catttgaacc tgcctctaag tatgctgtgt
    10621 gtatttctat aagtttctct ggattttgaa taccaaatac ttctggattt tcacctagct
    10681 ttaacccttt ttgttgaagc attgttccca ttgcaccatc gaatattaat atattatttt
    10741 tcagatattg tcttatttcc acaagagttc gctccttttc tatatgtaca gtttctatag
    10801 tttttacaat tttcacacga cttttctttc ttagatttat ttattcttgt atcagaaata
    10861 cctataatag ccactaccga ctttcttggt atcataattc cattagaagt aattgttaga
    10921 cctatttgtt tttgagcatt taaaacgttt aatatatcta tatttttttc tattggtaaa
    10981 tctccatatc ctggactata tcgcatagtt ataaatttat tttgttttaa aaaaaccttt
    11041 tctacattat cttgaacaat gtcacacact tcttctattg ctgttgttcc acatgaatca
    11101 attattagtc cttttgttaa atctgaataa gagtgtcgcc ttatttcttt ttctatatct
    11161 atccctatag tagctgccat aattacacat tcattacatt cttttaaaag ttcatataca
    11221 tctttactct ctaaagttaa atttgttccc tctaattcta caatattatc tttatttatt
    11281 ctaataggat aaatcctaga taaatatcta ggatttattt tatttttagt tatagctaca
    11341 cattcatcaa tagtatcttt aaggtcttta tctatctctt gacctctgta ttgtaaatat
    11401 cttaaaactt cactttgatt tatgcttata tcttctcttc caattaaatt attctccata
    11461 tatatttaaa gaaaatcctt tatctaaaac atcttttgca tattcctttg ctccaaataa
    11521 agataagtct ctgtagtttc cacattctat agctgtagct gctggcattt tatctgattc
    11581 aagaactttt tttaatgctt cttctaaacc aatcttaact gttttggcat ctacatctcc
    11641 ccatagtatt aaataaaatc ctgttctaca tcccattgga gataaatcta ttacaccatc
    11701 taatgtatct cttaaatagg tagccaaaag atgctctaaa ccgtgcatag cagcagttcc
    11761 aaaactttct acatttggct gtaaaaatct caagtcaaat ttagttactt tatctccctt
    11821 tactccatca agtacactac actttcttac aaaaggagct tttacttttg tatggtctag
    11881 cttaaaactt tctacttttt ccattattta atcctccatt atactttaaa atttgttaca
    11941 ttaattctaa aaaaaactct tcctatctat tattgataag aagagtatat tatttcaagt
    12001 catctcatcg ttgttagcag gaccacctga taaaaggttg gtataggatc actgagctaa
    12061 ctctctcccc taactcttga taagtatctt attaaactga cttaaattat atattacttt
    12121 tttatttttg taaacacttt attgttataa tatttatatc acgtaatcgt acttttattt
    12181 tataactaag ctgattgtat tattggcagt tgtacctcaa atacagtttg atatttatca
    12241 cttgaaacag taatttctcc accatgtaaa tttacaatat tttttgtaat tgcaagaccc
    12301 aacccagaac ctccaacatt tctatttctc gatttttcaa ctctataaaa tctatcaaat
    12361 atatttggta aatctaacac aggaattggt tctccataat ttatcacttt tacaaccgct
    12421 atatctccct ttttctctgt aactatatct acataaagtc catcttttcc atattttaca
    12481 gcattagtta taaggttttc aaatgctctt actaatttat tcggatcagc ttttacaatt
    12541 aatttttctt cattaaaatt aattctacta accataaatt cttgtttaaa ataaatttca
    12601 aattgagata ttacctgact taacaattct actaaattta tttctatttt gtttaatttt
    12661 attgtattat tctgcatttt agtcaattca aacaaatcat ttataagaac gttcaaattt
    12721 ttcgattttt catatgcaat atcaacataa tacatcatct gaacttcatc tttatactta
    12781 ccttcttcta taactcctaa ataacccatt atggatgtca aaggtgtcct taagtcatgt
    12841 gacacatttg ttattaaatc tgtttttgtc tgctgagctt gtctctcttc aatagttata
    12901 tttctaagtt gatgaacgat attattgatt ttatatgcta gttcatcgat atcatccttt
    12961 tcgttatctt ttaatatatc taagtcatat tcaatatcta tacttttttc taaattacct
    13021 tcatccatta aatttacagc actcttaatg atttctaatt tttgattttt tctattagtc
    13081 tttcttataa aatctacaat ttgcttattt ctcttgtacg atattatgga ataaattgct
    13141 aatgatgtga ttgtaaataa aaatggataa aataaactct ctcctataag acttctgaaa
    13201 tctcttaact gatatacaag ttgattaatt acagatatcg caccattgaa atataatgat
    13261 tttattatat acatacttgt tacaataagc attgaagtta aagcacagct tattataaga
    13321 tctaatatag gtcgaaacat atgatttaat aagcttttat ttttcaattt tatatcctac
    13381 tccccataca gtatgaatta ttttttctcc atctgtatat ttttcaattt tatcccttat
    13441 tctgctcata tgaaccatta cagtattatt agattggtaa tatttctctt tccacacttt
    13501 ttcaaatatt tcttctgtac tatatactct acctttattg tttgctagta aatataatat
    13561 atcaaattct cttgatgtca ggattatgtc atttccagct actgttacac tatgtttttc
    13621 cttatctata attactgctc caacttctat gacatcttta tcttcattat tagcaccact
    13681 aaaatagtat gctcttctaa tcagtgactt cactctcaca gtaagttcaa gtgggttaaa
    13741 tggttttgtc aaataatcat ctgcaccagt cattatccct tgtattttat ccatgtcttc
    13801 tgattttgca cttaacataa gtattggtat attcaaactt tctctaactt ttctacaaac
    13861 ttctattcca tccattttag gcatcattat atccaatacc attaaatgaa tattttcctt
    13921 ttttaaaata tctagagcct cttttccatc ttcagcttta attacattat atccactatt
    13981 taaaagatat atctctataa ggtctcttat ttccttttca tcatccacaa caagaattgt
    14041 attcttcact tttacacatc ctaacttaat ctttgtatat agttttattc atataaaatt
    14101 atactatatt ttagttagtg taatctataa atttattcat ttctaaattt ccaatataat
    14161 acaacttatt tacatattta tattatttgt tttgtaaata ttcttctaaa gttaatcctt
    14221 ttgaataaat ttcctcggca gcatccttac caacatatct aatatgccat ggctcatatg
    14281 ctgtacctgt tatatcttct ttaccttcag gatatcttat tataaatcca aacttgtgag
    14341 cattttctgc caaccattta gcttcttttg tacttccaac aaaccatctt tctggatttg
    14401 ttaaatcaat acaaagtcca gtttggtgct cactgtaacc aggctttgct acatatgcat
    14461 ctgccttttc tcgcccctga gattttaccc ttcttgtata agtatccagt tgagtatcat
    14521 aagatctgta tgctgaagac cctaaaaact gtattccttc tgaattagct tgcttaacta
    14581 aatcttcaac tgcctttgca ggttctcctg ccatttgttt ttcttcctct gttgcttctt
    14641 caacaaaagg tatgtttacc ttagtaatat tttcaggagt atagttttta ctaattccat
    14701 ttgtcttgtt taccaataat atatttgata tactatttga gtgattttta ttttgagaat
    14761 ttgcctcaac atcttgtttt gaataatgtt gagcaattac tgttggttct ttatctttct
    14821 taagtaatct atctttagat ataaatacac ttataaatac taccaaaata atagctacta
    14881 ttaatttaaa ttttttcata attaaatatt ctccttttca ttatgtttgt ctataatgtt
    14941 gattttagag tataagactt aagtatttta taagtaaatc ttaaataaat cttaaattta
    15001 atattattaa aggatggtga taaaatgtct atacaaaaac ttctaagtaa agctcgtaag
    15061 gctatacaag attttgatat gatacaagaa aatgataaaa ttgcagttgg actttctggt
    15121 ggaaaagata gtttaactct acttcatata cttaaaagtt atcaaaggtt ttctccacaa
    15181 aactttgaat tgatagccat aacattaaat actggaggtg ttgataattc tccactagat
    15241 aaattgtgta aagagataaa tgttcctttt tatgaatttc aaactgacat aaaagaaatc
    15301 gtatttgata taagaaaaga aaagaatcct tgtgcattat gtgctaatct aagaagaggt
    15361 gctttgaatg ataatgctaa aaaacttgga tgtaataaag tagctcttgg gcatcataaa
    15421 gatgatgcaa ttgagacatt tttaatgtct atgttttatg aaggcagagt aaattgtttt
    15481 tccccaaaga catacctaga tagacaggat ttgacggtta taagacctat gatttacata
    15541 gaagagtata tgactaaaaa aatctcaaaa gattctaact atcctattat aacaaatcca
    15601 tgccctgcaa atggtcatac tagaagagag tacataaaaa atcttattgc taatttaaat
    15661 aaagaaatgc ctgattttaa aagaaatgta tttggtgctc taaataattc tgagaaatta
    15721 tttatatggg ataaagagaa gataaaaaat tttaaatagt aattaaaatt tttaaataaa
    15781 aaagaaagat tgtattaatt gtaaataatc tttatataat ctacacaatc t
//
LOCUS       DAMKOJ010000080        15791 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000080 DAMKOJ010000000
VERSION     DAMKOJ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.086"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            118..672
                     /gene="tcdR"
                     /locus_tag="PC592_002843"
     CDS             118..672
                     /gene="tcdR"
                     /locus_tag="PC592_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HDF4056791.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLNYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKTKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            990..8090
                     /gene="tcdB"
                     /locus_tag="PC592_002844"
                     /gene_synonym="toxB"
     CDS             990..8090
                     /gene="tcdB"
                     /locus_tag="PC592_002844"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HDF4056792.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIVESAINDTLESFREN
                     LNNPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKIYLSNEYSKEI
                     DELNTYIEESLNKIKQNSGNDVRNFEEFKNGESFKLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPGYTSEH
                     FDMLDEEVQSSFESALASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTVNLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWTFDDARAKVQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSILFQKNIENSEVAYYYNPG
                     DGEIQEIDKYRIPSIISDRPKIKLTFIGHGKDEFNTDIFAGLDVDSLSTEIETAIDLA
                     KEDISSKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINNEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNLSDIELEEKVMLAECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     NEFKLIESISDSLYDLKQQNELDDSHFISFEDISKTEDGFSIRFINKETGESIFVETE
                     KEIFSEYANHIEREISNIKDTIFDTVNGKLVKKVNLDAIHEVNTLNAAFFIQSLIGYS
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     VIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTAATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHISLVETEGAFTLLDDKIMIP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTNDIDHFFSSPTITYIKPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENEGTKLLDRIRDHYKGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNNRSFIVPIITTEHIREKLSYSFHGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIDSDKIKKGDLIEGILSTLSIE
                     DNKIILNHHEINFSGDVNGSNGFISLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSFTLQDEKTIKL
                     NGVHLDESGVAEILKFMNKKGSTNTSDSLMSFLESVNIKSIFVNFLQSKINFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETTYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNNYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIISAFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPTNGGAASIGETIINDKNYYFNQSGILQTGVFS
                     TEDGLKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFEDNYRGAVEWKELDGEMYYF
                     SPETGKAFKGLNQIGDDKYYFNSDGIMQKGFVSINDKKYYFDDSGVMKVGYIEIDGKY
                     FYFAENGEMQIGVFNTSDGFKYFAHHNEDLGNEEGEAISYSGILNFNNKIYYFDYSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYVGLSLINDGQYYFNDDGIMQVGFVTINNKVFYFS
                     DSGIIESGVQNIDDNYFYIDEKGIVQIGVFDTSDEYKYFAPANTVNDNIYGQAVDYSG
                     LVRVGEDIYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEN
                     GIMRTGLISFENNDYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTQDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8212..8712
                     /gene="tcdE"
                     /locus_tag="PC592_002845"
     CDS             8212..8712
                     /gene="tcdE"
                     /locus_tag="PC592_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HDF4056793.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAVLLDAMTDEM
                     NAKDEK"
     gene            8791..8952
                     /locus_tag="PC592_002846"
     CDS             8791..8952
                     /locus_tag="PC592_002846"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056794.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYMDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9041..9223
                     /locus_tag="PC592_002847"
     CDS             9041..9223
                     /locus_tag="PC592_002847"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056795.1"
                     /translation="MRDEGQNDRENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9440..>15791
                     /gene="tcdA"
                     /locus_tag="PC592_002848"
                     /gene_synonym="toxA"
     CDS             9440..>15791
                     /gene="tcdA"
                     /locus_tag="PC592_002848"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HDF4056796.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFVNYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     LLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNEVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKDSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDTSVSPDTKFILNNLKLNIESSVGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDLLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKEYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNAIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIKTENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENNGTKLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNGSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQAKV
                     NGLYLNESVYSSYLDFVKNADGHHNTSNFMNLFLDNISFWKLFGFENINFVVDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLVYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEASKLVKGLININNSLFY
                     FDPIESNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNNGVMQLGVFKGPD
                     RFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSGSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAE"
BASE COUNT         6386 a         1652 c         2467 g         5286 t
ORIGIN      
        1 attttcatat aaaacttaat ttattttcta atcatacaat tataatgact gatttaatgc
       61 atatgttgtc aatttttttt aaaaaatcat cattataaaa taagagagga tgattttatg
      121 caaaagtctt tttacgaatt aattgtttta gcaagaaata actcagtaga tgatttgcaa
      181 gaaattttat ttatgtttaa gccattagta aaaaaactta gtagggtttt aaattatgaa
      241 gagggagaaa cagatttaat aatatttttt attgaattaa taaaaaatat taaattaagt
      301 agcttttcag aaaaaagtga tgctattata gttaaatata ttcataaatc attattgaat
      361 aagacttttg agttatctag aagatattct aagactaagt ttaattttgt agaatttgac
      421 gaaaatatct taaatatgaa aaataattat caaagtaagt ctgtttttga ggaagatatt
      481 tgttttttcg aatatatttt gaaagaatta tctggtattc aaagaaaagt tattttttat
      541 aaatatttaa aaggatattc tgatagagaa atatcagtga aattaaaaat atctagacaa
      601 gctgttaata aggctaaaaa tagagcattt aaaaaaataa aaaaagacta tgaaaattat
      661 tttaacttgt aattaatgag tttaaagaaa tatttacaat agaaatcaaa ttttagaatt
      721 aactttattg taaaatcaat aacttaatct aagaatatct taatttttat attttatata
      781 gaacaaagtt tacatattta tttcagacaa cgtctttatt caattgaaga gcaaattaat
      841 caactgagtg tcttcgattt aaaatgttag gaagtgaatg tatatgaaaa cctaagtaga
      901 tattagtata ttttataaat agaaaggagg atatataaaa gagttttagc atttagatgt
      961 aaaaatatta tagtaaagga gaaaatttta tgagtttagt taatagaaaa cagttagaaa
     1021 aaatggcaaa tgtaagattt cgtactcaag aagatgaata cgttgcaata ttggatgctt
     1081 tagaagaata tcataatatg tcagagaata ctgtagtcga aaaatattta aaattaaaag
     1141 atataaatag tttaacagat atttatatag atacatataa aaaatctggt agaaataaag
     1201 ccttaaaaaa atttaaggaa tatctagtta cagaagtatt agagctaaag aataataatt
     1261 taactccagt tgagaaaaat ttacattttg tttggattgg aggtcaaata aatgacactg
     1321 ctattaatta tataaatcaa tggaaagatg taaatagtga ttataatgtt aatgtttttt
     1381 atgatagtaa tgcatttttg ataaacacat tgaaaaaaac tatagtagaa tcagcaataa
     1441 atgatacact tgaatcattt agagaaaact taaataaccc tagatttgac tataataaat
     1501 ttttcagaaa acgtatggaa ataatctatg ataaacagaa aaatttcata aactactata
     1561 aagctcaaag agaagaaaat cctgaactta taattgatga tattgtaaag atatatcttt
     1621 caaatgagta ttcaaaagag atagatgaac ttaataccta tattgaagaa tccttaaata
     1681 aaattaaaca gaatagtgga aatgatgtta gaaactttga agaatttaaa aatggagagt
     1741 cattcaaatt atatgaacaa gagttggtag aaagatggaa tttagctgct gcttctgaca
     1801 tattaagaat atctgcatta aaagaaattg gtggtatgta tttagatgtt gatatgttac
     1861 caggaataca accagactta tttgagtcta tagagaaacc tagttcagta acagtggatt
     1921 tttgggaaat gacaaagtta gaagctataa tgaaatacaa agaatatata ccaggatata
     1981 cttcagaaca ttttgacatg ttagatgaag aagttcaaag tagttttgaa tctgctctag
     2041 cttctaagtc agataaatca gaaatattct catcacttgg tgatatggag gcatcaccac
     2101 tagaagttaa aattgcattt aatagtaagg gtattataaa tcaagggcta atttctgtga
     2161 aagactcata ttgtagcaat ttaatagtaa aacaaatcga gaacaggtat aaaatattga
     2221 ataatagttt aaatccagct attagcgagg ataatgattt taatactaca acgaatacct
     2281 ttattgatag tataatggct gaagctaatg cagataatgg tagatttatg atggaactag
     2341 gaaagtattt aagagttggt ttcttcccag atgttaaaac tactgttaac ttaagtggcc
     2401 ctgaagcata tgcggcagct tatcaagatt tattaatgtt taaagaaggc agtatgaata
     2461 tccatttgat agaagctgat ttaagaaact ttgaaatctc taaaactaat atttctcaat
     2521 caactgaaca agaaatggct agcttatgga catttgacga tgcaagagct aaagttcaat
     2581 ttgaagaata taaaaggaat tattttgaag gttctcttgg tgaagatgat aatcttgatt
     2641 tttctcaaaa tatagtagtt gacaaggagt atcttttaga aaaaatatct tcattagcaa
     2701 gaagttcaga gagagggtat atacactata ttgttcagtt acaaggagat aaaattagtt
     2761 atgaagcagc atgtaactta tttgcaaaga ctccttatga tagtatactg tttcagaaaa
     2821 atatagaaaa ttcagaagtt gcatattatt ataatcctgg agatggtgaa atacaagaaa
     2881 tagacaagta tagaattcca agtataattt ctgatagacc taagattaaa ttaacattta
     2941 ttggtcatgg taaagatgaa tttaatactg atatatttgc aggtcttgat gtagattcat
     3001 tatctacaga aatagaaaca gcaatagatt tagccaaaga ggatatttct tctaagtcaa
     3061 tagaaataaa tttattagga tgtaatatgt ttagctactc tatcaacgta gaagagactt
     3121 atcctggaaa gttattactt aaagttaaag ataaaatatc agaattaatg ccatctataa
     3181 gtcaagactc tattatagta agtgcaaatc aatatgaagt tagaataaat aatgaaggaa
     3241 gaagagaatt attggatcat tctggtgaat ggataaataa agaagaaagt attataaagg
     3301 atatttcatc aaaagaatat atatcattta atcctaaaga aaataaaatt acagtaaaat
     3361 ctaaaaattt acctgagctg tctacattat tacaagaaat tagaaataat tctaatttaa
     3421 gtgatattga actagaagaa aaagtaatgt tagcagaatg tgaaataaat gttatttcaa
     3481 atatagatac acaaattgtt gaggaaagga ttgaagaagc taagaattta acttctgact
     3541 ctattaatta tataaaaaat gaatttaaac taatagaatc tatttctgat tccttatacg
     3601 atttaaaaca acaaaatgaa ttggatgatt ctcattttat atcttttgag gatatatcaa
     3661 agacagaaga tggatttagt ataagattta ttaataaaga aactggagaa tctatatttg
     3721 tagaaactga aaaagaaatt ttttctgaat atgctaatca tatagagaga gaaatttcta
     3781 atataaaaga tactatattt gatactgtaa atggtaagtt agtaaaaaaa gtgaatttag
     3841 atgctataca tgaagtaaat actttaaatg ctgcattttt tatacaatca ttaataggat
     3901 atagtagttc taaagaatct cttagtaatt taagtgtagc aatgaaagtt caagtttatg
     3961 ctcaattatt tagcactggt ttaaatacta ttacagatgc agccaaagtt gttgaattag
     4021 tatcaactgc attagatgaa actatagact tacttcctac attatctgaa ggattacctg
     4081 taattgcaac tatcatagat ggtgtaagtt taggtgcagc aatcaaagag ttaagtgaaa
     4141 ctagtgaccc attattaaga caagaaatag aagctaagat aggtataatg gcagtaaact
     4201 taacagcagc tacaactgca atcattactt catctttagg gatagctagt ggatttagta
     4261 tacttttagt tcctttagca ggtatttcag caggtatacc aagcttagta aataatgaac
     4321 ttgtacttag agataaggca acaaaggttg tagattattt taaacatatt tcattagttg
     4381 aaactgaagg agcatttact ttattagatg ataaaataat gataccacaa gacgatttag
     4441 tgatatcaga aatagatttt aataataatt caatagtttt aggtaaatgt gaaatctggc
     4501 gaatggaagg tggctcaggt catacagtaa caaatgatat agatcacttc ttttcatcac
     4561 caacaataac atatataaaa ccacacttat ctatctatga tgtattggaa gtacaaaaag
     4621 aagaacttga tttgtcaaaa gatttaatgg tattacctaa tgctccaaat agagtatttg
     4681 cttgggaaac aggatggaca ccaggtttaa gaagtttaga aaatgagggt acaaaactgt
     4741 tagaccgtat aagagatcac tacaaaggtg agttttattg gagatatttc gcttttatag
     4801 ctgatgcttt aataacaaca ttaaaaccac gatatgaaga tactaatata aggataaatt
     4861 tagatagtaa caatagaagt tttatagttc caataataac tacagaacat ataagagaaa
     4921 aattatcata ttctttccat ggctcaggag gaacatatgc attatctctt tctcaatata
     4981 atatgggtat aaatatagaa ttaagtgaaa gtgatgtttg gattatagat gttgataatg
     5041 ttgtgagaga tgtaactata gactctgata aaattaaaaa aggtgattta atagaaggta
     5101 ttctatctac actaagtatt gaagataata aaatcatctt aaatcatcat gagattaatt
     5161 tttctggaga tgtaaatgga agtaatggat ttatttcttt aacattttca attttagaag
     5221 gaataaatgc aattatagaa gttgatttat tatctaaatc atataaatta cttatttctg
     5281 gcgaattaaa aatattgatg ttaaattcaa atcatattca acagaaaata gattatatag
     5341 gattcaatag cgaattacag aaaaatatac catatagctt tgtagatagt gaaggaaaag
     5401 agaatggttt tattaatggt tcaacaaaag aaggtttatt tgtatctgaa ttacctgatg
     5461 tagttcttat aagtaaggtt tatatggatg atagtaagcc ttcatttgga tattatagta
     5521 ataatttgaa agatgtcaaa gttataacta aagataatgt taatatatta acaggttatt
     5581 atcttaagga tgatataaaa atctctcttt cttttactct acaagatgaa aaaactataa
     5641 aattaaatgg tgtgcattta gatgaaagtg gagtagctga gattttgaag ttcatgaata
     5701 aaaaaggtag tacaaatact tcagattctt taatgagttt tttagaaagt gtgaatataa
     5761 aaagtatttt cgttaatttc ttacaatcta aaattaactt tatattagat gctaatttta
     5821 taataagtgg tactacttct attggtcaat ttgagtttat ttgtgatgaa aatgataata
     5881 tacaaccata tttcattaag tttaatacac tagaaactac ttatacttta tatgtaggaa
     5941 atagacaaaa tatgatagta gaaccaaatt atgatttaga tgattctgga gatatatctt
     6001 caactgttat caatttctct caaaagtatc tttatggaat agacagttgt gttaataaag
     6061 ttgtaatttc accaaatatt tatacagatg aaataaatat aacgcctgta tatgaaacaa
     6121 ataataatta tccagaagtt attgtattag atgcaaatta tataaacgaa aaaataaatg
     6181 ttaatatcaa tgatctatct atacgatatg tatggagtaa tgatggtaat gattttattc
     6241 ttatgtcaac tagtgaagaa aataaggtgt cacaagttaa aataagattc gttaatgttt
     6301 ttaaagataa gactttggca aataagctat ctttcaactt tagtgataag caagatgtgc
     6361 ctgtgagtga aataatctca gcatttacac cttcatatta tgaggatgga ttgattggct
     6421 atgatttggg tctagtttct ttatataatg aaaaatttta tattaataac tttggaatga
     6481 tggtatctgg attaatatat attaatgatt cattatatta ctttaaacca ccagtaaata
     6541 atttgataac tggatttgtt actgtaggtg atgataagta ttactttaat ccaactaatg
     6601 gtggagctgc ctcaattgga gagacaataa ttaatgacaa aaattattat ttcaaccaaa
     6661 gtggaatctt acaaacaggt gtatttagta cagaagatgg acttaaatat tttgccccag
     6721 ctaatacact tgatgaaaac ctagaaggag aagcaattga ttttactgga aaattaatta
     6781 ttgacgaaaa tatttattat tttgaagata attatagagg agctgtagaa tggaaagaat
     6841 tagatggtga aatgtactat tttagcccag aaacaggcaa agcttttaaa ggtctaaatc
     6901 aaataggtga tgataaatac tattttaatt ctgatggaat tatgcaaaaa ggatttgtta
     6961 gtataaatga taagaaatat tattttgatg attctggtgt tatgaaagtg ggttatattg
     7021 aaatagatgg caagtatttc tactttgctg aaaatggaga aatgcaaata ggagtattta
     7081 atacatcaga tggatttaaa tattttgctc atcataatga agacctagga aatgaagaag
     7141 gtgaagcaat ttcatattct ggtatattaa atttcaataa taaaatttac tattttgatt
     7201 attcatttac agctgtagtt ggatggaaag atttagagga tggttcaaag tattattttg
     7261 atgaagatac agcagaagca tatgtaggtt tatcattaat caatgatggt caatattatt
     7321 ttaatgatga tggaattatg caagttggat ttgtcactat aaataataaa gttttctact
     7381 tctctgattc tggaattata gaatctggag tacaaaatat agatgataat tatttctata
     7441 tagatgagaa gggtatagtt caaattggcg tatttgatac ttcagatgaa tataaatact
     7501 ttgcacctgc taatactgta aatgataata tttacggaca agcagttgac tatagcggtt
     7561 tagttagagt tggtgaagat atatattatt ttggagaaac ctatacaatt gagactggat
     7621 ggatatatga tatggaaaat gaaagtgata aatattattt caatccagaa actaaaaaag
     7681 catgcaaagg tattaattta attgatgata taaaatatta ttttgatgag aatggcataa
     7741 tgagaacggg tcttatatca tttgaaaata atgattatta ctttaacgag aatggtgaaa
     7801 tgcaatttgg ttatataaat atagaagata agatgtttta ttttggtgaa gatggtgtca
     7861 tgcagattgg agtatttaat acgcaagatg gatttaaata ctttgcacat caaaatactt
     7921 tggatgagaa ttttgaggga gaatcaataa actatactgg ttggttagat ttagatgaaa
     7981 agagatatta ttttacagat gaatatattg cagcaactgg ttcagttatt attgatggtg
     8041 aggagtatta ttttgatcct gatacagctc aattagtgat tagtgaatag ataaaaatat
     8101 gttaaatata tcctcttata cttaaatata taaaaataaa caaaatgata cactacataa
     8161 agtgttctat ctaatatgaa gatttaccaa taaaaaggtg aactatgatg aattcacagt
     8221 agttcacctt tttatatttc taatggtaac aaaatatttt tttatataaa cctaggaggc
     8281 gttatgaata tgacaatatc ttttttatca gagcatatat ttataaagtt agtaatttta
     8341 actatatcat ttgatacatt attaggatgt ttaagtgcaa taaaaagtcg taaatttaat
     8401 tctagttttg gaatagatgg aggaatcaga aaagtagcaa tgatagcatg tatatttttt
     8461 ttatcagtag ttgacattct tacaaagttt aactttttat ttatgttacc acaagattgt
     8521 atcaattttt taagactaaa acatcttgga atatctgaat ttttctctat tttatttatt
     8581 ttatatgaaa gtgtaagtat attaaaaaat atgtgcttat gtggattacc agtacctaag
     8641 agattaaagg aaaaaatagc agttttacta gatgcaatga cagatgaaat gaatgctaag
     8701 gatgaaaagt aagtactggt agatataata aagatattaa caaataaaaa gtgttatcca
     8761 aataagaata gctgaaagtt atcataattc atgaaactga taatgaaaac gagggagcag
     8821 atgccaagag acacacaagt attaaataca tataatttcg aagcaagtgt tcattactat
     8881 atggatgaca aggtagtata tcaaacattg gttcacaaag atggtgcatg gtcagttggt
     8941 aaaatctatt aagctacatt agttacagat atcacaaact ataatagtta aacatagaaa
     9001 tatgtgtaaa ttgtgatgga aattattcaa aaacacaaaa atacgtgatg aaggacaaaa
     9061 tgatagagaa aataagtatc aaaccttaat aaatgattta attgatagtt taaaagttat
     9121 aggaaaaata tataaagaaa taaaaacatt aaaaaaatat aagatatgtt tacaaattac
     9181 tatcagacaa tctccttatc taatagaaga gtcaattaac taattgagta tctttaaatt
     9241 gaaatgttag gaagtgattt aaatatgaaa acttaaatta taaaaaatca atattaattt
     9301 atttttaaaa aatagaaagg agtgtataag atttattttc aaagtttaaa aaaaagaaaa
     9361 tcaatttaaa tttcagaagg aataaatgtg gttatagaag tggatttatt atcaaaaata
     9421 ataatactag gaggttttta tgtctttaat atctaaagaa gagttaataa aactcgcata
     9481 tagcattaga ccaagagaaa atgagtataa aactatacta actaatttag acgaatataa
     9541 taagttaact acaaacaata atgaaaataa atatttacaa ttaaaaaaac taaatgaatc
     9601 aattgatgtt tttatgaata aatataaaaa ttcaagcaga aatagagcac tctctaatct
     9661 aaaaaaagat atattaaaag aagtaattct tattaaaaat tccaatacaa gccctgtaga
     9721 aaaaaattta cattttgtat ggataggtgg agaagtcagt gatattgctc ttgaatacat
     9781 aaaacaatgg gctgatatta atgcagaata taatattaaa ctgtggtatg atagtgaagc
     9841 attcttagtc aatacactaa aaaaggctat agttgaatct tctaccactg aagcattaca
     9901 gctactagag gaagagattc aaaatcctca atttgataat atgaaatttt acaaaaaaag
     9961 gatggaattt atatatgata gacaaaaaag gtttgtaaat tattataaat ctcaaatcaa
    10021 taaacctaca gtacctacaa tagatgatat tataaagtct catctagtat ctgaatataa
    10081 tagagatgaa actttattag aatcatatag aacaaattct ttgagaaaaa taaatagtaa
    10141 tcatgggata gatatcagag ctaatagttt gtttacagaa caagagttac taaatattta
    10201 tagtcaggag ttgttaaatc gtggaaattt agctgcagca tctgacatag taagattatt
    10261 agccctaaaa aattttggcg gagtatattt agatgttgat atgcttccag gtattcactc
    10321 tgatttattt aaaacaatat ctagacctag ctctattgga ctagaccgtt gggaaatgat
    10381 aaaattagag gctattatga agtataaaaa atatataaat aattatacat cagaaaactt
    10441 tgataaactt gatcaacaat taaaagataa ttttaaactc attatagaaa gtaaaagtga
    10501 aaaatctgag atattttcta aattagaaaa tttaaatgta tctgatcttg aaattaaaat
    10561 agctttcgct ttaggcagtg ttataaatca agccttgata tcaaaacaag gttcatatct
    10621 tactaaccta gtaatagaac aagtaaaaaa tagatatcaa tttttaaacc aacaccttaa
    10681 cccagccata gagtctgata ataacttcac agatactact aaaatttttc acgattcatt
    10741 atttaattca gctaccgcag aaaactctat gtttttaaca aaaatagcac catacttaca
    10801 agtaggtttt atgccagaag ctcgctccac aataagttta agtggtccag gagcttatgc
    10861 atcagcttac tatgatttca taaatttaca agaaaatact atagaaaaaa ctttaaaagc
    10921 atcagattta atagaattta aattcccaga aaataatcta tctcaattga cagaacaaga
    10981 aataaatagt ctatggagct ttgatcaagc aagtgcaaaa tatcaatttg agaaatatgt
    11041 aagagattat actggtggat ctctttctga agacaatgag gtagacttta ataaaaatac
    11101 tgccctcgat aaaaactatt tattaaataa taaaattcca tcaaacaatg tagaagaagc
    11161 tggaagtaaa aattatgttc attatataat acagttacaa ggagatgata taagttatga
    11221 agcaacatgc aacctatttt ctaaaaatcc taaaaatagc attattatac aacgaaatat
    11281 gaatgaaagt gcaaaaagtt actttttaag tgatgatgga gaatctattt tagaattaaa
    11341 taaatatagg atacctgaaa gattaaaaaa taaggaaaaa gtaaaagtga cctttattgg
    11401 acatggtaaa gatgaattca acacaagcga atttgctaga ttaagtgtag attcactttc
    11461 caatgagata agttcatttt tagataccat aaaattagat atatcaccta aaaatgtaga
    11521 agtaaacttg cttggatgta atatgtttag ttatgatttt aatgttgaag aaacttatcc
    11581 tggtaagtta ctattaagta ttatggacaa aattacttcc actttacctg atgtaaataa
    11641 agattctatt actataggag caaatcaata tgaagtaaga attaatagtg agggaagaaa
    11701 agagcttcta gctcactcag gtaaatggat aaataaagag gaagctatta tgagcgattt
    11761 atctagtaaa gaatacattt tttttgactc tatagataat aagctaaaag caaagtccaa
    11821 gaatattcca ggattagcgt caatatcaga agatataaaa acattgttac ttgatacaag
    11881 tgttagtcct gatacaaaat ttattttaaa taatcttaag cttaatattg aatcttctgt
    11941 tggtgattac atttattatg aaaaattaga acctgttaaa aatataatcc acaattctat
    12001 agatgattta atagatgagt tcaatctact tgaaaatgta tctgatgaat tatatgaatt
    12061 aaaaaaatta aataatctag atgagaagta tttaatatct tttgaagata tctcaaaaaa
    12121 taattcaact tattctgtaa gatttattaa caaaagtaat ggtgaatcag tttatgtaga
    12181 gacagaaaaa gaaatttttt caaaatatag cgaacatatt acaaaagaaa taagtactat
    12241 aaaaaatagt ataattacag atgttaatgg taatttatta gataatatac agttagatca
    12301 tacatctcaa gttaatacat taaacgcagc attctttatt caatcattaa tagattatag
    12361 tagcaataaa gatctactga atgatttaag tacctcagtt aaggttcaac tttatgctca
    12421 actatttagt acaggtttaa atactatata tgactctatc caattagtaa acttaatatc
    12481 aaatgcagta aatgatacta taaatgtact acctacaata acagagggga tacctattgt
    12541 atctactata ttagacggaa taaacttagg tgcagcaatt aaggaattac tagacgaaca
    12601 tgacccatta ctaaaaaaag aactagaagc taaggtgggt gttttagcaa taaatatgtc
    12661 attatctata gctgcaacgg tagcttcaat tgttggaata ggtgctgaag ttactatttt
    12721 cttattacct atagctggta tatctgcagg aataccttca ttagttaata atgaattaat
    12781 attgcatgat aaggcaactt cagtggtaaa ttattttaat catttgtctg aatctaaaga
    12841 atatggccct cttaaaacag aagatgataa aattttagtt cctattgatg atttagtaat
    12901 atcagaaata gattttaata ataatgcgat aaaactagga acatgtaata tattagcaat
    12961 ggagggggga tcaggacaca cagtgactgg taatatagat cactttttct catctccatc
    13021 tataagttct catattcctt cattatcaat ttattctgca ataggtataa aaacagaaaa
    13081 tctagatttt tcaaaaaaaa taatgatgtt acctaatgct ccttcaagag tattttggtg
    13141 ggaaactgga gcagttccag gtttaaggtc attagaaaat aatggaacta aattacttga
    13201 ttcaataaga gatttatacc caggcaaatt ttactggaga ttctatgcct ttttcgatta
    13261 tgcaataact acattaaaac cagtgtatga agacactaat attaaaatta aactagataa
    13321 agatactaga aacttcataa tgccaactat aactactaac gaaattagaa acaaattatc
    13381 ttattcattt gatggagcag gaggaactta ctctttatta ttatcttcgt atccaatatc
    13441 aacaaatata aatttatcta aagatgattt atggatattt aatattgata atgaagtaag
    13501 agaaatatct atagaaaatg gtactattaa aaaaggaaag ttaataaaag atgttttaag
    13561 taaaattgat ataaataaaa ataaacttat tataggcaat caaacaatag atttttcagg
    13621 cgatatagat aataaagaca gatatatatt cttgacttgt gagttagatg ataaaattag
    13681 tttaataata gaaataaatc ttgttgcaaa gtcttatagt ttgttattgt ctggagataa
    13741 aaattatttg atatccaatt tatctaatac tattgagaaa atcaatactt taggtctaga
    13801 tagtaaaaat atagcgtaca attacactga tgaatctaat aataaatatt ttggagctat
    13861 atctaaaaca agtcaaaaaa gcataataca ttataaaaaa gacagtaaaa atatattaga
    13921 attttataat ggcagtacat tagaatttaa cagtaaagat tttattgctg aagatataaa
    13981 tgtatttatg aaagatgata ttaatactat aacaggaaaa tactatgttg ataataatac
    14041 tgataaaagt atagatttct ctatttcttt agttagtaaa aatcaagcaa aagtaaatgg
    14101 attatattta aatgaatccg tatactcatc ttatcttgat tttgtgaaaa atgcagatgg
    14161 acaccataat acttctaatt ttatgaattt atttttggac aatataagtt tctggaaatt
    14221 gtttgggttt gaaaatataa attttgtagt cgataaatac tttacccttg ttggtaaaac
    14281 taatcttgga tatgtagaat ttatttgtga caataataaa aatatagata tatattttgg
    14341 tgaatggaaa acatcgtcat ctaaaagcac tatatttagc ggaaatggta gaaatgttgt
    14401 agtagagcct atatataatc ctgatacggg tgaagatata tctacttcac tagatttttc
    14461 ttatgaacct ctctatggaa tagatagata tatcaataaa gtattgatag cacctgattt
    14521 atatacaagt ttaataaata ttaataccaa ttattattca aatgagtact accctgagat
    14581 tatagttctt aacccaaata cattccacaa aaaagtaaat ataaatttag atagttcttc
    14641 ttttgagtat aaatggtcta cagaaggaag tgactttatt ttagttagat acttagaaga
    14701 aagtaataaa aaaatattac aaaaaataag aatcaaaggt atcttatcta atactcaatc
    14761 atttaataaa atgagtatag attttaaaga tattaaaaaa ctatcattag tatatataat
    14821 gagtaatttt aaatcattta attctgaaaa tgaattagat agagatcatt taggatttaa
    14881 aataatagat aataaaactt attactatga tgaagctagt aaattagtta aaggattaat
    14941 caatataaac aattcattat tctattttga tcctatagaa tctaacttag taactggatg
    15001 gcaaactatc aatggtaaaa aatattattt tgatataaat actggagcag ctttaactag
    15061 ttataaaatt attaatggta aacactttta ttttaataat aatggtgtga tgcagttagg
    15121 agtatttaaa ggacctgata gatttgagta ttttgcacct gccaatactc agaataataa
    15181 catagaaggt caggctatag tttatcaaag taaattctta actttgaatg gcaaaaaata
    15241 ttattttgat aatgactcaa aagcagtcac tggatggaga attattaaca atgagaaata
    15301 ttactttaat cctaataatg ctattgctgc agtcggattg caagtaattg acaataataa
    15361 gtattatttc aatcctgaca ctgctatcat ctcaaaaggt tggcagactg ttaatggtag
    15421 tagatactac tttgatactg ataccgctat tgcctttaat ggttataaaa ctattgatgg
    15481 taaacacttt tattttgata gtgattgtgt agtgaaaata ggtgtgttta gtggctctaa
    15541 tggatttgaa tattttgcac ctgctaatac ttataataat aacatagaag gtcaggctat
    15601 agtttatcaa agtaaattct taactttgaa tggtaaaaaa tattactttg ataataactc
    15661 aaaagcagtt actggatggc aaactattga tagtaaaaaa tattacttta atactaacac
    15721 tgctgaagca gctactggat ggcaaactat tgatggtaaa aaatattact ttaatactaa
    15781 cactgctgaa g
//
LOCUS       DAMKOJ010000081        15612 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000081 DAMKOJ010000000
VERSION     DAMKOJ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15612
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.087"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(39..728)
                     /locus_tag="PC592_002849"
     CDS             complement(39..728)
                     /locus_tag="PC592_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDF4056797.1"
                     /translation="MYNVLHTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIIGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIAGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMIASTVFKLGNINHPVAKGIALGTSAHALGTTKAFEFGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            complement(721..1092)
                     /locus_tag="PC592_002850"
     CDS             complement(721..1092)
                     /locus_tag="PC592_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDF4056798.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            complement(1274..2620)
                     /locus_tag="PC592_002851"
     CDS             complement(1274..2620)
                     /locus_tag="PC592_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF4056799.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKAFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDISKNEETKKVKRKKNILPYIIVGCVLIGMGLYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPERKITVADEEDLYYQAL
                     DLKKKKEYEKAIENFKSIVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            complement(2802..3395)
                     /locus_tag="PC592_002852"
     CDS             complement(2802..3395)
                     /locus_tag="PC592_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HDF4056800.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            complement(3460..4914)
                     /locus_tag="PC592_002853"
     CDS             complement(3460..4914)
                     /locus_tag="PC592_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF4056801.1"
                     /translation="MSNMNKKLVIAIGAVALVAIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVEFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SGFFGNLSKTISANFGKKSNLVVVVNYDKNKLKAEMGKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDVSKSMETFDNQTKKGNYKNKLAVKATPAKVKKEQLANIDTNLGKY
                     STTFKTSQINRSINIKLATDSISNILLMPGETFSFNEHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIANVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPS
                     TDENKNNQNTNNQQKPETPPTDNKPNETPPQPQD"
     gene            complement(5029..6420)
                     /locus_tag="PC592_002854"
     CDS             complement(5029..6420)
                     /locus_tag="PC592_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDF4056802.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIVLMIVFFLSSNE
                     FSVGKEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELKKISIDVDDLLAQADRVREMYKEENTTYDIAINYIN
                     TVSLLNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKVYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKEDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNALDEKE
                     NKYKKIEILDIEKADRYSKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAVSENGLNEY"
     gene            complement(6586..6834)
                     /locus_tag="PC592_002855"
     CDS             complement(6586..6834)
                     /locus_tag="PC592_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056803.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTFGIVL
                     CNARKIFDSKTIHKTRMKNVSTNKKQKSHSRDIKRKIS"
     gene            7100..9229
                     /locus_tag="PC592_002856"
     CDS             7100..9229
                     /locus_tag="PC592_002856"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDF4056804.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGSIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNAEE
                     VNKKIDNTCSWKKEHTKNIENECNCEHEHHDYMNKALDCKQEHMTDIKDDCNQEKKHT
                     KNTNKTHSSKQNKFKDKSCDEMKFNYDKDESCDKINSSYDKDDSSYEYFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKAEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGIVSRPQDRENFTLLLTAIR
                     DVIGDEKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNARKHQSN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPFLVKDGEFAMAYDDSLSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            complement(9442..10041)
                     /locus_tag="PC592_002857"
     CDS             complement(9442..10041)
                     /locus_tag="PC592_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HDF4056805.1"
                     /translation="MAKQKFYAVKKGKNIGIYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIYGAEKFSFKEDKEFIEAYVDGSYEHSIKMYGSGVVILKNNEVIKTYSEKGKEE
                     TLVGMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10058..13177)
                     /locus_tag="PC592_002858"
     CDS             complement(10058..13177)
                     /locus_tag="PC592_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HDF4056806.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYYMPKLKNKFIDLIELAVILEPYYKDYSLEYLKNTLTNFNSKVENRALSDAIDII
                     NIVNCLLVRFNSYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINLKK
                     EYNIFDSKEEKKKERETLKILNEEENHYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLE
                     RLVEGGKYGDIEEINYSVFDNFKEISIHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIEREDKQKIARSINLIIEEIDSIL
                     NFGSCNEYDSVSNYNLRWELNLQIDEILGKLKKDGVDTEISYRAYSEKIKLGCEKIIK
                     NLVLIIITIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISQITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYNIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRQHLNKSRSLILKSVIFDTIKA
                     LNVDSKMNNNDVDKDIIKKDINENIRQRAVKGEVYHIDILKKDIKVKYFNKNYLINLD
                     IFMREENKN"
     gene            13400..14224
                     /gene="pdaA"
                     /locus_tag="PC592_002859"
     CDS             13400..14224
                     /gene="pdaA"
                     /locus_tag="PC592_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF4056807.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYDAYYVGNPKEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPDLIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEREGYKLKTLDYLSNKK"
     gene            complement(14320..15105)
                     /locus_tag="PC592_002860"
     CDS             complement(14320..15105)
                     /locus_tag="PC592_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4056808.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVKDGNITSIILKNKSTLIIYSFKNNFDIEEMKNHIKNLDVESISGKKCVIDRLISE
                     YKNFYEKLDNKFCVLKEMKEIDFSNMKGYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRKNDTMISTVSTGMETSFLAMVVSISTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDIAGKIYHNIGYKEVNEWTILFK"
BASE COUNT         5171 a         2531 c         1566 g         6344 t
ORIGIN      
        1 gttttaagta ttcaagatac ttatcttaat tttatttttt atataaaatt cattataatt
       61 ggaattagta ttactgtaat tgtaccagaa actccaatag aaacaccact catagctccc
      121 tctatttctc caaattcaaa agcttttgtg gttcctaaag catgtgcaga cgttccaaga
      181 gcaattcctt tagcaactgg atgatttata ttcccaagtt tgaatactgt agaagcaatc
      241 ataccgccaa aaatacctgt aaaaattatg gctacaactg ttattgattc tataccattt
      301 aaagaatttg ctaaagatat tcccattggt gttgttatag attttggaat cagtgaattt
      361 attatactta catctgaatt agctattttg ccaattatca atacagatac aaaagaaatc
      421 actataccac aacctattcc cgcaatgatc tcaaacatat gctttttaaa tagttcaaat
      481 tgtttataaa gcggaactgc aagcactact gtgacaggac ctaaaaagaa atttagacta
      541 tctgccccta tcttataatt ctcataagga attttagata tacttaaaaa taatattatt
      601 cctatgattg caattaatag aggattacat ataggattac ttgtttttct ttgaatatat
      661 cttcctaaat taaaaaatac tattgttact attataccaa atactggcgt gtgcaataca
      721 ttatacattt ttttgtcctt cttccttctt ttttatcatc ttttccacta taattccagt
      781 agtatacatt actattagtg tacttaaaca tatgactaat aaaagtacta atacattttc
      841 ccttattaaa tctaatgact ttataagtga tacacctgct ggaataaaaa atatagccat
      901 attatcgagg aaaaatccac ttacattttc tatactactc aaatctaaaa ctttaaattg
      961 taatagtaga aataatagca gcataccaac tatactccca ggaataagta taattccttg
     1021 tataaaggaa cttatatact ctcctattac ccagatagat aaaattatta ctaattgatt
     1081 gaaaactttc attttccacc tccaaaaact aaagagattg cttcaaatca tatatttgta
     1141 gttttatcaa caagcaaata tctttcttta aaatagaaag ttataatttg atacaatctc
     1201 tttttaaatt tatttttatt ttaatttaat aaaatacata cttggttgtt tcaaaaaact
     1261 taactatata aacctatttt tcacttaaaa tttcttttat ttttgaattg ttatacatac
     1321 tgtctggaac ttcacttctc aaactataaa aagtctgttg tgcatttttt aaatcgccat
     1381 tatcataata aagcataccc aactcgtaat atgaatcatc ataatactgg tcatttttag
     1441 tataagtatt tatatatttt ttgtaatatt ttatagcttc atccttattt cccaataact
     1501 tatttgttat tgctaattga tatattgatt cagaaatata ttttttagtt tttccagaag
     1561 aaactatact tttgaaattt tctatagctt tttcatattc tttctttttc tttaaatcta
     1621 gagcttgata atataaatct tcctcatcag ctacagttat ctttctttct ggttctttat
     1681 ttttaacctc atttaattcc ttattcgttt tttctaattt tttactcgtt tcccctaact
     1741 ttttatcagt ttcacttaac ttttcttctt tgctacttat ttgattattt aaattttcta
     1801 ttcttttttt gctttgaatt aaatataaac ccatgcctat taaaacacaa ccaactataa
     1861 tatatggtaa aatatttttc tttcttttta ctttttttgt ttcttcattt ttacttatgt
     1921 cttctttttc ttcttcattt ttttcaaaaa caggattatc tttatctaat tctttaagtt
     1981 tgtctaaata tccctctctc ttttttacat tacctagttt atcatatagc aaagataaaa
     2041 ttacatatgg ttctattagt tctggttctt cttcaattat gttctctaga atatgtattg
     2101 actcataatt taattcttca tttataaatc ttatagaatg attgtatctt cctaaaaaag
     2161 ttttaaaatc ttcagatgaa attagattta catactttct agatatatga ttattttcat
     2221 aacataaagc agtataaaaa ctctcaaatg ctttggcaaa atcacatttt aataacttta
     2281 aaagacctct aagatttaat atatcaatgt ctttaggatt tatctctaga gctttattta
     2341 ccatattaat ggcactagtt atataatttt tatatgctaa atccaatgca ttattatatc
     2401 ttttatatga ttctaatttt aactccttag atgttgtgtc tgactttgaa tttaaagctc
     2461 cttgcaagtt taataatgtt tcttctttat aattcgtagt tacataactc tgttttaatg
     2521 cttttaatgt ttcatcacca tcttcttctt ctatattaaa aaaagttaaa tcacttttat
     2581 tatcttctat caaagatata tctaaaattt ttctaggcat gctttctata tcttgtttta
     2641 tatctttaac taaaataata ctcacctcca ctctaaaata tatatttaag ataacatatt
     2701 taatatgtca agtcaaaact atacatattt ttccactatt ttcataataa aaaaggtaat
     2761 cctcttcttt tcataaaaag gttacctctt tttcaatact attaactttt aatgttgaat
     2821 ttttttactt ttctatagag tgtagctata cctatattca atgcctcagc tacttttttc
     2881 attccttctg tgttgcttcc atattttttt atagcatttt ctatagcttc cctctcaagg
     2941 tcatctatag ttttaacttc ttgtttataa agttcatcta gtttaaaaga tattaaatca
     3001 gacatactcc ttacaaaagc agttaactcc ttatcttttg aaagtatctt ttctttttgt
     3061 tcttcattaa acgcagctat acccaagatt ccaagtatat gctctcccat tttaacggga
     3121 gtacatatat cagctaactc tttacaattt tctctatttg cacatttatt acagttctct
     3181 tctatttcct tatttataac ataggatttt ccatctttta aaacaagaga gtacactgac
     3241 ttctctgata ttgtctctcc tattttaccc ctgaatattc ctgtacctgc tatcctagtt
     3301 aaatcttttg taaccaaagt aacatctaca tccaagacat tagaaatatt ctcgcaaata
     3361 ctttgaacgt aattcgttat attatttaaa ttcaaagtaa tccctcctat ttagatttat
     3421 attttttatt actctacata aatcctattc ttgagaactt taatcttgcg gttgtggtgg
     3481 tgtctcatta ggcttattat cagttggtgg tgtttctggt ttttgttgat tgtttgtatt
     3541 ttgattattc ttattttcgt ctgtacttgg tttttcctct ggttttggtt ccatagtacc
     3601 aactaatata ataccttcct ttttaggata atatgaatta gctatttttt cagttttaat
     3661 tttcttacca tttgcatcgt taaatgttct atatgttgat acagaatatg catttcttcc
     3721 acttttatct actttttctt tacctttagg cattgtaggg tcattaactc ttttcattgt
     3781 agtctgtgaa acaccatcta attttgttga tattgttata ttttgtttat cttctgcact
     3841 tccatatatg ttacaaacaa tttgatttcc tgaaacgtaa ttttttatgt aaaccggatg
     3901 ctttagatta tttttaaaca agaaatctat accactatct gcaacagttg catctcttcc
     3961 ttttggaaca tagcttgatg gtatagtatg attttttaca ttagcaattt ctagacctgc
     4021 atataacaca gaattgtata atgtagatga aacttgacaa actcctccac cataatcttc
     4081 ttccatctca ccttccatta ttacaggtgc actcttatac ccattttcct tacttctttt
     4141 ccctgtatgc tcgttaaatg agaaagtttc tcctggcata agtaatatat tacttatgct
     4201 atccgttgct aattttatgt ttatacttct atttatttgg gaagtcttaa atgttgttga
     4261 atacttacct aagtttgtat ctatgttagc aagttgctct ttttttactt ttgctggagt
     4321 agcttttact gctaacttat ttttatagtt acctttttta gtttgattat caaaagtctc
     4381 catactcttg gaaacatcca ttttaagacc atcagaatct ggtataacct taactttttc
     4441 accacttata tctaatgtag catcttttac atctacatct atttctttag ctatttttcc
     4501 catttctgct tttaatttat ttttatcata atttaccaca actactaagt tgctcttctt
     4561 gccaaaattt gctgaaatag tttttgatag attaccaaag aaaccactct ttctatttaa
     4621 attatatgcg ttttctactg ttttatccag gtcagtagat aaatttaaat ccttgctttt
     4681 tactttccag cttttatcat tgtaattaaa ctcaacattc tctaatttgt attttttagc
     4741 taattcctgt tttgcttgcg atttagttaa ttttccaata tttactccat taacatatgt
     4801 gttttttgct attttctccc ctttaaattg catgcacatt atgcctataa aaattattgc
     4861 tactaatgcc acagctccaa tagctataac tagctttttg ttcatattac tcatcccata
     4921 cttctcctta caataaaatt atttacatat ccctattatt atattactac ataatgcgcc
     4981 ttaaaacccc aaaaactttt taattatata ttaatttaat attattaatt aatattcgtt
     5041 tagtccattt tctgatacag catatatttt ttcattgtaa atattaatag cataaacttc
     5101 ttttcctcta aataagcctt tatttactac agcataataa taaatatttt tatattttcc
     5161 aaacaattct tctaagctct ttttactttt tgaatatcta tcagctttct ctatatctaa
     5221 tatctcaatc ttcttatact tattttcttt ttcatcaaga gcattagtta acacaaattt
     5281 agctttatct tttgtaatac caaattgata acttccatct tctaatattc taaagtatcc
     5341 atcaccataa tctactttgt aatctttttt cccatcttta tacgaatata aatctttagt
     5401 ttttgcactt accaaaactt catttattaa tttatcgtac tcatatactt cagcataata
     5461 gtatttattg ttttttatca tctgtggaag tgagtttata gataaatttg ccttgtcttt
     5521 accgcttttt ttagctatta catttataat gtcatcagat gttaaagtat acaatgataa
     5581 attcttttta tatttttttt ctaaactctg caccttttca tcatctgaat aatcttcttt
     5641 taaatattca atatattgta atgctctttc ataatctcca gaagtatttg cctcttcagc
     5701 tctgcttata tagtaatcat acatctcttc aatacattgt tctttcccat tttgagccat
     5761 actgtaatac ttctcatctt cttttaatac tttattatac ttttcaatag cttcataata
     5821 cttatatact ttttggtctt ttactgctga gtcataaaca tctctagact ctttaattgt
     5881 ttctatattc tgtttgtata catctaggtt actacccata ccatttaata gcgaaacagt
     5941 gtttatgtag ttaatggcaa tatcataagt ggtattttct tctttataca tttctctaac
     6001 tctatcagct tgagctaata agtcgtccac atctatactt atttttttta attctttcac
     6061 tgtatttatt agtccaataa agctttcttg acttatatct ccatctaaat atttatcacc
     6121 actatttaat agtaatttat ttattttttt agaaacagac ttattaaatc tttccatttt
     6181 tgaatcagaa aacttttttt ctatacttgt gtagtaatca acagctatag aatactgtct
     6241 tttttctata atctttaaca gctcattagc ttcttttcct acactaaact cgttactact
     6301 taagaaaaat actatcatca aaacaattac acctaatgtt gataatgaaa ttgcaactat
     6361 agatttcctt ttttcatcaa taaaatctac agccttctca aataaatctc taaaattcat
     6421 tatagttccc tctccattta ataatcttta tattttatgg taaactaaat ttcttattgg
     6481 ttattatatc ataattcttg aaaaaaaata aaaacacaag ttaaatcgtg tttttatttt
     6541 acctatcaat cattatttta tacataaata tttcctttac ataaattatg atatctttct
     6601 ttttatatct ctagaatgac tcttttgttt tttattagta ctgacatttt tcattcttgt
     6661 tttatgtata gttttgctat caaatatttt tctagcattg cataaaacaa ttccaaatgt
     6721 taaacaaact gtaagcacac ttcccatcaa aaagtaataa tccaatccta tatggactcc
     6781 cataactgaa tttattaata ctaatgcaaa agtcattgca aaacatatca tcatggagat
     6841 aactaaaatt cttagaattt ttttcaatcc actcacctcg tataatcact aaaattgaca
     6901 ctactcctta tccattacta taccaaatta gtaaaaaaat agcaattact attgtcattt
     6961 atattaggaa aatattaaat ctttttaata aatatctttt tttgacataa ggattactta
     7021 acttttaata aagtagtaac actaatatgt attaattaat agaataaaat aaatgataat
     7081 ttattgaggg gtgatttaca tgccaaattt gccaagttta gggtcaaagg ctcctgattt
     7141 taaagccaat acaacaaacg gatctattag actctctgat tataagggta attggattgt
     7201 tttattttca catcctggtg attttacacc agtttgtacc acagaatttt tatgttttgc
     7261 taaatattat gacgaattta aaaaaagaaa tacagaacta ataggtctaa gcgttgatag
     7321 taacagctca catttagctt ggatgtataa tatttcttta cttacaggtg tagaaattcc
     7381 atttcctatt atagaagata gagatatgag aattgccaag ttatatggca tgatatcaaa
     7441 accaatgagt gatacatcaa ctgttcgctc tgtatttatt atagataata atcaaattct
     7501 aagaacaatt ctttattatc cactaactac aggaagaaat attccagaaa tacttagaat
     7561 agtagatgca cttcagacta gtgatagaga taatatagtt actcctgcaa actggtttcc
     7621 tggaatgcca gtgattttac cttatcctaa aaactataag gaattgaaaa atagagttaa
     7681 cagttgtaat aagaaatatt catgtatgga ctggtactta tgttttgtac cagataatta
     7741 taatgctgaa gaagtgaaca agaaaattga taatacttgt agctggaaaa aagaacatac
     7801 taaaaacatt gaaaatgaat gtaattgtga acatgaacat catgattaca tgaacaaagc
     7861 tcttgactgt aaacaagaac acatgactga tattaaagat gattgcaacc aggagaaaaa
     7921 acatactaaa aatactaaca aaactcacag ttccaaacaa aataagttta aagataaatc
     7981 ttgtgatgaa atgaagttta actatgacaa agatgaatct tgcgataaaa taaattctag
     8041 ctatgacaaa gatgatagta gttatgaata tttctataaa cacaattata aaaactacga
     8101 ttatactagt gaaaaaaata ctaaaaaaat agctatgaaa actttaaaag attcaaaaaa
     8161 actagttaga ccacaaataa cagacccata caacccaata gttgaaaatg caaactgtcc
     8221 agatataaat ccaattgtag cagaatatgt tcttggaaat ccaactaatg tagatgctca
     8281 actgttggat gcggttatat ttgcctttgc tgaaatagac caatctggaa atttatttat
     8341 tccttatcct aggtttttaa accaactact tgctcttaaa gctgaaaaac ctagcttaaa
     8401 agtaattgta gctattggag gttggggagc tgaaggattc tctgatgcag cattaacacc
     8461 tacatctaga tataattttg caagacaggt taatcagatg ataaatgaat atgctttaga
     8521 tggaatagat atagactggg aatatcctgg aagtagtgca tctggaatag tatcaagacc
     8581 tcaagataga gaaaacttta cacttttatt aacagctata agagatgtta taggagatga
     8641 aaaatggctt agtgtagctg gaacaggaga tagaggatat ataaattcaa gtgctgaaat
     8701 agataaaata gctccaataa tagattattt taatcttatg agttatgatt ttacagcagg
     8761 tgaaacaggt ccaaatgcta gaaaacatca atcaaacctt tttgattctg atttatcctt
     8821 accaggatat agtgttgatg caatggtaag aaatcttgaa aatgctggaa tgccttctga
     8881 aaaaattctt cttggcatac cattttatgg aagattaggt gctactataa caagaactta
     8941 tgatgaactt agaagagatt atataaataa aaatggatat gagtatagat ttgacaatac
     9001 tgctcaagtc ccatttttag ttaaggatgg agagtttgca atggcctatg atgattcttt
     9061 atccatattc ttaaaaactc aatacgttct tagaaattgt ttaggtggtg tattctcatg
     9121 gacatcaact tatgaccaag caaatatatt ggctagaacc atgtctattg gtataaatga
     9181 ccctgaggta ttaaaagaag aacttgaagg tatttatggg caattctaat agaatgtagt
     9241 aagattttat agttatataa aaaagcagat tttattatat taaataagct gtgtctaatt
     9301 aacactgatg ttaattgttt ataaattaga tacttatttt ctcataatat aatctgcttt
     9361 ttaaatcaaa ttttatttaa ttataaatta ggggtttaga tatactcttg tagcatgtca
     9421 ttatgtataa atattttttt attatacacc aatagctttt ttagctaatt tatcagcttc
     9481 ttcattatac ttatttccag aatgagcttt aacctttgta aattttacat taagcttatt
     9541 cttaatgcta tcataaaaat ttttatatgc tatagttcct tctttatttg ttttccaaac
     9601 tccagtacac cacttttcaa taccttcata gtcaaaatat aaaatcaagt tttgaacatt
     9661 attgtcaata cagtactgca ttgcaatttt agaagcttct atctctccag ctacatttct
     9721 catacctact agagtttcct cttttccttt ttcactataa gtttttataa cttcattatt
     9781 ttttagaatc acaacacctg aaccatacat ctttattgaa tgttcataac ttccatctac
     9841 atatgcttct ataaattcct tatcttcttt aaaactaaat ttttctgccc cataaatata
     9901 ttctttagct tcttgaaaag tagaaaaact cttatattca gctcctgaga atccatttac
     9961 ttgctttttg cactcatccc atgtattata tatacctata tttttacctt ttttcacagc
    10021 ataaaacttt tgttttgcca aatatatcac tccactctta atttttattt tcttctctca
    10081 taaatatatc taaatttata agataatttt tattaaaata ttttacttta atatcttttt
    10141 tcaaaatatc aatatgatat acttctcctt ttacagctct ttgtcttata ttttcattaa
    10201 tatctttttt tataatatct ttatcaacat cattgttatt cattttagaa tcaacattca
    10261 acgcttttat agtatcaaat ataacagatt ttagtattaa gcttctagat ttatttaaat
    10321 gttgtcttat ataagtataa aactcattgc tattaacctt tgaaatttta caatcgtgta
    10381 aatctttctc taatctcttt aacacactta tattagttcc tacatcaaaa atgacaaaac
    10441 atccatagtc gtatttactt cttaaaattc tccccatagc ttgctttacc tttatggtca
    10501 tttgaggata atttatagta tagtagtcta tattatactt cttcattata gtaaaataca
    10561 aagggtcttt tggatttaga ttcggaagct tgtctaaagt tacacaaacc aaaccatccc
    10621 ctggaatatc tactccttca aaacatcctt ttgagccaag tactacacac tttctattta
    10681 aatcgttaag gtgcctaatt ccttttttat cagcataaat ttctaaatta aaactatgta
    10741 agtatttttt caatatttca taagtctttt cttgtctatc tttactatta aaaagagcta
    10801 atgtatgacc ttctgtaatc tgtgatatat tagatataat tttactcatt tcatttggaa
    10861 attcagaatt tctgtactca caaatatcag aaaacccaac tacagagact ctatttttat
    10921 aatcaaaaat tggttctata atcttttcca cattcttaac tctgtctatt cctaatgtat
    10981 ttttaaaata agacatactt tcagataaac tcaaagttgc agataaaaat attcctttct
    11041 ctaattgaga taaaatattt tcttcaaata aatctgctat ttttaatggc actactcgaa
    11101 attcaaagtc attataattc ttatcaattt caactatcct tgcataatca tctttttcat
    11161 catactctaa aaagatttca aatataatct ttatatcctc taaatctctt gtttttgcct
    11221 ttccaaattt atatatatct gcttctttat ctatactatc atcatcaata ttcctataaa
    11281 ttgttattat tattaaaact aaatttttta ttattttttc gcaacccaat tttatctttt
    11341 cactataagc tctataactt atctcagtat ctacaccatc tttttttagt tttcccaata
    11401 tttcatctat ttgcaaattc agttcccatc ttaaattata attgcttaca ctatcatatt
    11461 cattacaact accaaaattt aatattgaat ctatctcttc aataataaga tttatacttc
    11521 tagcaatttt ttgtttatct tccctttcaa tttttaatac attataaaat ttatcaaaag
    11581 cctttatttt cctcatattt ctgctatatt ttttatatat aaagctacta ttttgaataa
    11641 actcgtaagg ataaatttct tgtaataaat accttaagga ctttgagttt ataatgcttg
    11701 aaaagaaatc atatcctttt tcagtcaaat tatgtgcttc gtctactatt atattttcta
    11761 aaggtttttc atccttatac ggccatttag ctaatagtga atgatttact actgttatat
    11821 gttcttcttt caattcttct attctgtttt tatatagaca atcttttttg cattttttag
    11881 gtctacacat atttgggtca caacttacat ttcttaagtg aatacttatt tccttgaagt
    11941 tgtcaaacac cgaataattt atttcttcta tatctccata cttaccacct tcaactaatc
    12001 tctccaaaaa tattaaagat aaaatttctc ctttagtagg attttgagac tcataatcat
    12061 ctatatatgc ttccagtcta tctatacaaa tatagttatt ttttcccttt atatatccat
    12121 aacttacttt tccatttagc cctaaagaat ctaacacgtt tggaatatct ttatttatta
    12181 attgtatctg caattccttt gtatcagtag aaattaataa tcttttttta ttaattctag
    12241 cttctaatat tgcaggcagt aaatatccta cacttttacc tataccagtt ggcgcttcta
    12301 tacatgcaat tttttcttca tcttcgctat ttctaaacaa ctctcttatt gttttagtaa
    12361 gctcatattg accaggccta tattcatatg taaatccttc tttattctcc catatagttt
    12421 tgtattttaa taattcttca taatgatttt cttcttcatt taaaattttt aaggtttctc
    12481 tttccttctt tttttcttct ttcgagtcaa atatattata ttcttttttg aggtttatat
    12541 tatttgataa atcataattt gcctcttcta aaaatttgct ccattcccat gttgggagat
    12601 taaatttttt aagatatgag tttattttaa aactcaatgg ttccaaagta gttttttcat
    12661 agctattaaa tcttactaga aggcaattta caatatttat tatatcaata gcatctgaca
    12721 aagctctatt ttccacctta gaattaaaat ttgttaaagt attttttaag tattctaaac
    12781 tataatcttt ataatatggt tctaaaataa ctgctaattc aattaaatca ataaacttat
    12841 tttttaactt tggcatataa tactcaaaaa actttttttt cagacttaaa tcatgacata
    12901 taatgaaact atcttctaca aaatttacaa gtctatcttc caccagttct atttcattag
    12961 ctatttctaa atcattttta tctaaatttt tacatactga gaatacttct ataggtacct
    13021 caaatttgtt ttttattaat gattcatagg tatatatttt ccagtcttta accttgacag
    13081 ctccaacttc taaaatttct gaatttaaac aatctaatcc actaacttct atatctaaaa
    13141 aaacaacatc attcaataca cttattatat tatccatttt tatatccctt caagttaaac
    13201 ccgcctaact tatttacaat catttctctt tatattttat catttatata cactttattt
    13261 aagataatta atagtaactt tatatatctt acagtaaact tctttcattt attatttgta
    13321 tatatgaata tttttaacta taaatattca aactatatta taagaaatat actttaaatt
    13381 ttaaataaga ggtgaaattg tgaaaaaaga tagcctaaaa aaatacatta tgataggagc
    13441 atttgcccta atactttttg gaattgctag tataaatttt aaatcattag ataaaacaaa
    13501 aactcaaatt tctagtccaa cactcgacac acatgaatat gattggtatt ttaaccctag
    13561 agaggatggt aaacagccat cacctataaa agaagctgat ttttttaaaa aatatgatgc
    13621 ttattatgta ggaaatccca aagaaaaagt tatatatcta tcatttgatg ctggatatga
    13681 aagtggaaac actccaaaat tattagatac actaaaaaaa cacaatgcta aagcacaatt
    13741 tttcgtagtt gaaagttata taaaaagcaa tccagattta ataaagcgta tggaaaaaga
    13801 aggacattta gtttgtaatc attcaaaaag ccatccatca atggcaggta ttacagattt
    13861 tgaaaaattt aaagaagaaa ttacaagcgt agaaaaagca tacaaagatg ttactggaaa
    13921 agaaatgcct aagtatttta gacctccaat gggtaaattt agcgaacaat ctttaaaata
    13981 tacacaagat ttaggatata aatcaatatt ttggagtttt gcttatgtag attggtatga
    14041 aaagaaacaa cctactcatg aatttgccaa aaacaaaatt tattcaagaa ctcatcctgg
    14101 tgcaatagtt ttactgcatc caaattcatc aacaaatact gagatattag atgaggttct
    14161 tacacattgg gaaagagaag gttataaact taaaacactt gattatttaa gtaataaaaa
    14221 ataatatcat aaattaaaaa aaactccatc atgaattata gtaaaatata gctatttata
    14281 aatactttaa ttctcgatag agttttttat tttttatagt tatttaaaaa gaattgtcca
    14341 ttcatttacc tctttatatc ctatattatg atatatttta cctgctatat cattgttata
    14401 aaaaagacat ggaacttttc cttccagcaa taattcttta ctcaaattgt aaaccatgta
    14461 acttgcaagt ccttttcccc tatatctttt atctgtactt atagagacca ccattgccaa
    14521 aaaactagtt tccataccag ttgacacagt actaatcata gtatcattct ttctaataaa
    14581 atatgctctt acattcccct cttttaaatg ctcttttctt tcttctatat aatttttact
    14641 tactttataa tctgacctat ttaaaagttt tcctatttca tcaatatctt tttcctgagc
    14701 attttctatt ttatacccct tcatattgga aaaatctatt tctttcattt cttttaatac
    14761 acaaaattta ttatctagtt tttcataaaa atttttgtat tcacttatta gtctatctat
    14821 tacacacttt tttccactta tactttctac atctaaattt tttatatgat tcttcatttc
    14881 ttctatatca aaattatttt taaaactata aattataagt gtcgacttat tttttaatat
    14941 tatagaagtt atatttccat cttttacctg agaccatata tcttgatatt gagagctaaa
    15001 tccgtaattc tcaacgtatc caattatgaa taaatttaaa ctttcttcat gtgatacata
    15061 ttgccaaaat tctttttcta aagtattatc tatttttaca atcaagcaga tatcctcctt
    15121 ctatgttaat aatgatatac cttataattt atagtatcat ttaaaatcat tatattctac
    15181 caaatattct aaatttttaa atatttatgc aatatgttcg tatttatttt tatactctgt
    15241 tactgcttca ttccaagctt cttctactga tatacctctc ttatttgcaa ttttttgtgc
    15301 taattctatt attttcatag cttttcttga tatattcata tatattcctc ctctaaatta
    15361 tcataagtta ttttaaagtt aaatttctat agtcatgtta tatatttatt tacttatatc
    15421 ttactaatta tttatgtact aaatatgaac tacaatagaa gaaatttaga acttaataaa
    15481 acataaaatt tatatacaat tcatatatat ttgtcgtatt tatctagcta ttacaaataa
    15541 aaaacattca atatgttaaa aaagtaagtt tagtttactc tttaataatt taaaattaga
    15601 tactttttat at
//
LOCUS       DAMKOJ010000082        15565 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000082 DAMKOJ010000000
VERSION     DAMKOJ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15565
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.089"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            64..1125
                     /gene="ytvI"
                     /locus_tag="PC592_002861"
     CDS             64..1125
                     /gene="ytvI"
                     /locus_tag="PC592_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF4056809.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIKLITNNTNLNRTLISIVILLAFYGLCIFLLISFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALMLGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            complement(1280..2533)
                     /locus_tag="PC592_002862"
     CDS             complement(1280..2533)
                     /locus_tag="PC592_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF4056810.1"
                     /translation="MDLSSIFKHYCKECENTWNNSSVELFDNIETYSKDSQKKMEKEL
                     DKLINTISVHLERYPSDIVLRKMWVKKGEIFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDSDLPISDIMQAMRNVWISNALQVLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTSIDKNDKILFNNWLEKRLLGEHIKSNDYHESKVSQMIDYIESVYPREKFIEV
                     YESLLLIFKSQVKSLKQHGEENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEID
                     FCIGYGFLLQISDDLQDVKEDLKYNHKTIITEMAKEGNLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVERFIPYTIDYSLEIEEKMK
                     EKFKSIDVLNNENEYKEMIDIICAE"
     gene            complement(2634..4754)
                     /locus_tag="PC592_002863"
     CDS             complement(2634..4754)
                     /locus_tag="PC592_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDF4056811.1"
                     /translation="MGKVLVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVVTWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKEGFAKLKSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSRICNKLLKSNITANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKVTSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPIDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQKKNQETFNNPFAEALAKLKNK"
     regulatory      5181..5269
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            5459..6826
                     /locus_tag="PC592_002864"
     CDS             5459..6826
                     /locus_tag="PC592_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDF4056812.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILVSFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     gene            complement(6999..7646)
                     /locus_tag="PC592_002865"
     CDS             complement(6999..7646)
                     /locus_tag="PC592_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF4056813.1"
                     /translation="MLESLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKNTGYILITPS
                     GIGREELKVEHICVLDLDGNVIEFEKGIKPSSEVLMHIEIYKTRENVNAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKIVSKLLLDTDACLLERHGL
                     TTVGNDLAEALLKSRYVEDVAEIYYKSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(7664..8350)
                     /gene="araD"
                     /locus_tag="PC592_002866"
     CDS             complement(7664..8350)
                     /gene="araD"
                     /locus_tag="PC592_002866"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDF4056814.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNVVDGKLRPSSDTPTHLVLYREFEELGGIVHTHSSWATI
                     WAQIGKPIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNLMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            complement(8447..9505)
                     /locus_tag="PC592_002867"
     CDS             complement(8447..9505)
                     /locus_tag="PC592_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF4056815.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGECDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEKHVLKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIKAGDSVVVLGCGPIGQFSIQWARVFGASKVIAVDIFDEKLELSKFLGANYILNS
                     KEVNVIKEIKTITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATERILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            complement(9850..11256)
                     /locus_tag="PC592_002868"
     CDS             complement(9850..11256)
                     /locus_tag="PC592_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF4056816.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRITTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGIAVGIYFALWALFRKNKASIL
                     DYLEKQALKNVEEEPVAV"
     gene            complement(11435..11737)
                     /locus_tag="PC592_002869"
     CDS             complement(11435..11737)
                     /locus_tag="PC592_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF4056817.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            complement(11858..12304)
                     /locus_tag="PC592_002870"
     CDS             complement(11858..12304)
                     /locus_tag="PC592_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4056818.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKDTYINAVLERE
                     KTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLNVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNVKLLKNIKNASTKEEVAKLLDFIEI"
     gene            complement(12337..15240)
                     /locus_tag="PC592_002871"
     CDS             complement(12337..15240)
                     /locus_tag="PC592_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4056819.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISTILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     EVVEETEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIVGESGVGKSLFS
                     RHMYEFAKQKKIIKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDAPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     VEYTEIRKYLKNAIFIPFNLEEALVKGNLLSDKYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSSEDIFSMSDLNSFVNDSLVKLVKELMNDIVEKNI
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEAKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNINTKTID
                     RVDLLMALEAARKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENIKETSNILAIVGTINPKVPGINFI
                     PYNKEVFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGFIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDEEFMNNANKCFNKDAFKKIIFDKFKHL"
BASE COUNT         4930 a         2689 c         1774 g         6172 t
ORIGIN      
        1 gtatatttta tgtaaaaaag accatattta gaataatatt aaatacactg gaggttttat
       61 attatggaca ttcaaaagca aaagaatttt ataattaaat ttacatatgt agttttaata
      121 acaagtattg tatatattgt attaaaattc ttattgccat tactaatgcc ttttgtaata
      181 agttttatca ttgcatccat cctaagacct attataaaac ttattacaaa taatacaaat
      241 ttaaatcgta cacttatttc tatagtaata ctgttagctt tttatgggtt gtgtatattc
      301 ttattaatta gctttggtgt gaagatattt gcaagtgtaa gtgatgtatt ttttagactt
      361 cccgaaatat ataaatcaag tatacaacca acactaaata ctttattttc gaagatagat
      421 gctagtacac ctaatgttaa cctagcatta atgcttggtt gggataatat aagtcaatct
      481 atgatgtctt tagtagcttc tatttcaaca aatgcactta atgctattgc tagtattgca
      541 agtaaaacac ctgcatttat gttaaaactt attattactt taattgcttc ttttttcttt
      601 acttttgact atcaaaaaat agtaaacttt atcttaaaac aatttccaga aaaaagtcaa
      661 tttatgataa taaatataaa aaatagcagt attaatgctc ttttaaaact actaaaagct
      721 tacgcaatac tactatcagt gacattcata gaactactta ttggacttac tatcctaaaa
      781 gttgaaaatg catttactat atctgtcatc atagcacttg ttgatatttt gccagtcttg
      841 ggtacaggaa gtattctgac accttggatg attatatcac tcattaatgg aaatattaat
      901 ttagcaatag gacttttaat actatacata attataactg ttgttagaca aatattagaa
      961 ccaaaggtag tgggacacca aattggccta tatcctttaa taacattaat gtgtatgttt
     1021 gttggagctc aactatttgg aatagctgga ttatttggat tccctatcgc agctacaatc
     1081 ataaaaaact tacatgataa tgggattatt actgcattta aatagtttaa ccttgacatt
     1141 tttatttaaa ttaaaaaggg ctgtctcaaa tagagataag cctcttttta attgttagaa
     1201 tgatgaaaat acatttgatt ttatacaaaa agagtgcctt ataaactaaa aagtctattc
     1261 taagacactc cctttttttc tactctgcac aaataatatc aatcatttct ttatactcgt
     1321 tttcattatt taaaacatct atacttttaa atttttcttt cattttttct tcaatctcta
     1381 atgaatagtc tattgtatat ggaataaatc tctctacttc ttttatatat cctacagaaa
     1441 aaaattcagc attataaact acagaaaata aaattaacat taagcaatca ttctttatca
     1501 tagttattac agatttattt ttattgttaa ttttaaaact atctattaac tcaatagtaa
     1561 aatttattag tttatttaca actttatcta aattaccctc ttttgccatc tctgtaataa
     1621 tagttttatg gttgtatttt aaatcttctt ttacatcttg taaatcatca gatatttgta
     1681 ataaaaatcc atagccgata caaaaatcta tttcttcctt tgtcatcaat ccacttatta
     1741 aatatccatc tactaaaacg gatgaaccac ctttttcaat agaaatggat aataaatctt
     1801 ccttacacaa atgattttct tcgccatgtt gttttaaact ctttacttga cttttaaata
     1861 ttaataataa tgattcatat acttctataa acttttctct agggtataca ctttcaatat
     1921 aatctatcat ttgagatact ttgctctcat gatagtcatt agatttaatg tgttctccca
     1981 agagcctttt ttctaaccag ttattaaata aaatcttatc atttttatct atacttgtat
     2041 tgtctaaata attatcagta tatggatata acatactata tgcaaagtta gcttttgaat
     2101 aataaacttc tttaccaaat aatacttgta atgcatttga aatccataca ttcctcatag
     2161 cttgcataat atcacttata ggtaaatcac tatcaaattt tctagcatct ctaataaatt
     2221 gttttgttat atctaaaaat ttttttctat cctctacatc cattttttct aacttaaaaa
     2281 tattttcttt ttctaatgtc ttttgtaaga aaatctcgcc tttttttacc cacatttttc
     2341 tcaatacaat atcacttgga tacctctcta aatgaactga tattgtattt atcaatttat
     2401 ctaattcttt ttccatcttt ttttgtgaat ctttactata tgtttctata ttatcaaata
     2461 gttcaacact tgaattattc catgtatttt cacactcttt acaatagtgt ttaaatatac
     2521 tacttaaatc catttaacag ccctactttc atgcctaaac tatacactat attatatcag
     2581 tacatataac taatatacag ttaaagttat aattgtgtat aataacttta aaattatttg
     2641 ttttttagct tagctaatgc ttctgcaaat ggattattaa atgtttcttg atttttcttt
     2701 tgatttttta aatattgatt aacatctttt tttgatgcct tctgcttttc ttcttgcttt
     2761 ctcttgttaa aagaagatag cttttctctg tatccgcaac tacaagtgaa gattctccct
     2821 tctccttctc cacgaagttc taatttttta tgacaattag ggcatcttga attggttact
     2881 tgtgatatag tttttctagt attacactct ctgtcttcac aaatcaacat cttacctttt
     2941 ttaccattta cctctagcat aaatttacca cactctggac atctattttt agtcaagtta
     3001 tcatgtttaa atttattatc actatttttt acttctaata caatatcttt tgaataatct
     3061 ttcatatcat ttatgaatgt atttttacta agttttccct ttgaaatatc caataatttc
     3121 ttttcccatg aagctgtaag ttctggtgtc ttcaagtcta ttggaactaa atctaataat
     3181 tgtctccctt ttgatgttat atatatatct ttatttttct tttccattaa aaatgaattg
     3241 aataattttt ctattatatc tgctcttgta gcaactgtcc ctagaccgtt tttttccata
     3301 gcagtcagta atgttccctc atttaaatat ggtggtggat ttgtttttcc tgacgttacc
     3361 tttaatccct taaccttaag tacatctttt tctaaaacat ttggtatact ttcatactca
     3421 tcttcgtctt caatatcttt ataactttct ttccaaccta aatttattac tttgtttcct
     3481 ttagccttaa atatctctcc ttctacagtt gcacttatag ttgtctgctc atattcaaaa
     3541 ggaggagata gtactgctaa aaatcttttt actacaagat tatatatttt tcgctctttg
     3601 tcactaaaat cactcataaa taccttctgt tctgttggta ttattgcatg gtgatctgtt
     3661 acctttgaat tgtcaacaaa tgatttatta gctgtaatat tgctttttaa taatttatta
     3721 caaatccttg aataatcact aatatttaca gcttttattc tatcttttaa tgttccaaca
     3781 atatctgatg ttaaatatct agaatcagtt ctaggataag taagcacttt atgatgctca
     3841 tatagctttt gcattataga taaagtttct tttgctgaaa atccaaacat tttatttgca
     3901 tctctttgta attctgttaa atcatagagt gcaggtgaat attttttctt atatgatttg
     3961 tttacttcag atatttttat gtctacacct tttacttttt ttaatgtaga ttctatcttt
     4021 tctttactaa aagttgaaga gttattgttt ttatcattcc aaataaattt tatatctgaa
     4081 ttgccttttg tagcaattaa ttccaatcca tagtactcct tgggtttgaa atttcttatt
     4141 tcctcttctc ttttaagtaa cattgcaaga gtaggagttt gtactcttcc acaagaaagt
     4201 tgtgcattat actttgttgt caaagctctg gttgcattta ttccaataat ccaatcagct
     4261 tctgctcgcg ctattgccga ataatacaaa ttttcatatt cttttccact ttttaatttt
     4321 gcaaagcctt cttttattgc tttatctgta cttgaagaaa tccaaagacg ctttataggt
     4381 ttttttacct gtgatttttc tattatccat cttgctacaa gttctccttc acgacctgca
     4441 tctgttgcta taactatttc atctatatca tttctattca tttgcgattt gactgtatta
     4501 aactgctttc cactcttttt tatcacaaca gtcttaaggt gcttaggaag tattggcaag
     4561 tcttctaaac tccacgattt gtatctttct ccatagcttt cggggtcagc aagtgtaacc
     4621 aaatgaccta gtgcccaagt taccacatac tttggtccct ctatataacc atttttttca
     4681 ttttttgacc ctaaaacttt tgctatatct cttccaacag aaggtttttc tgctagtact
     4741 aatacttttc ccatctaaaa atacatcctt tctctataca taatctcata ttacgcttaa
     4801 aatctaagta aatagaactt ttcttaatat cgtaactata atattaccat aatttaatca
     4861 tatctaatta attatttaag attttattgt ttttttattt aaaacttatt ttacacctaa
     4921 tttgtatgtc tattacaaaa tttattttca cgtatattac tcatctttct aagtttataa
     4981 ttcgtaaata ggcttacatt tttatctttt ttctttgttt tttaattttt cagttgacaa
     5041 aacataaaaa cttatattaa tattattaat acaataagct atgacaaatc aatatccggt
     5101 taagatttta tagaagagtt gctatatggc acaccgaagg agtaacactc tcaggtactt
     5161 ttaaagtagg actgtaaaat ttacggaact ctggagagac ccattatggg cgccgaaggg
     5221 gcaaggcttt tatgctcaat ctctcaggca aaaggacagg gattatctac caaaaacagt
     5281 atttactaat acttttattt tggttgctaa ttagtgtaca tccagagctg aatctttttt
     5341 agatttagct ttttttatta cactagaaat tattaataaa ttatacttat ttcctgtcaa
     5401 ttacttcatt aaaaattcta ttgattatgt aaagcaaaaa aaatgaggga gtgtttttat
     5461 gaatctaatt gatattttaa acaaagttga tgcttttatt tggggaccac ccctactagt
     5521 actattagtt ggtactggta tactacttac tgttaaactt ggagttgttc aaataactaa
     5581 actaccaaga gctcttaagt taatattctc tgctgaaaac aaaggtagtg gtgatgtttc
     5641 aagttttgca gccttatgta ctgctttagc tgctacagtt ggtactggta atattgttgg
     5701 tgttgctaca gctatcaaag ctggtggacc tggtgcactt ttttggatgt ggatagcagc
     5761 attctttgga atggctacta agtattcaga aggtgttctt gcaataaaat acagaactaa
     5821 agataaaaat ggtcaagtgt ctggtggacc aatgtattac atagtaaatg gtatgggaga
     5881 aaaatggaga cctcttgcaa tatttttcgc tataagtggt atactagttg cacttttagg
     5941 aataggtact tttactcaag taaattcaat aacagacgca ataaataata gttttggtat
     6001 agaccctaga attacagggg ttgtattagc agtatttgta gctttggttg tatttggagg
     6061 tcttaaaagt atatctaacg tagctactaa aatagtacct tttatggcag ttatatacgt
     6121 tgtaatctgt ggaatcattt tagtatcttt ttggaataaa atccctgaaa cttttatgtt
     6181 aataattaaa agtgcattta cacctactgc tgctactggt ggttttctag gagcaactat
     6241 gtccttagca attagaaatg gtatcgctcg tggtgtattt tcaaatgagt ctggtctagg
     6301 tagtgctcca atagctgcag ctgctgctaa aactgaatgg ccagcggaac aaggtcttat
     6361 atctatgaca ggtactttta tagatactat tataatctgt actcttactg gattctctct
     6421 tgttatttca ggggtatggt gttcagacct aaatggagct gttatgacac aagcagcttt
     6481 taacggggct attcctacat ttggaccaat attacttaca gttagtttaa cattatttgc
     6541 atttactaca attttaggat ggagttatta tggagaaaga tgttttgaat ttctgtttgg
     6601 tgtaaaaggt atgaatgggt atagaactgt atttgtggct atggtgttat taggtgcatt
     6661 cttaaagtta gaagttgttt ggataattgc tgatatcgta aatggactta tggcaatacc
     6721 taacttgata gctttacttg cattatcacc tataatagta tctgaaacta aaaaatattt
     6781 tgaacatata aattcaccag aaaatcagat aaagaaaaat gcataaataa aaaatataga
     6841 atcccaagtc aattttatat ggctttcgga ttctatattt ttttgaaaaa atgtaataaa
     6901 tatatttaca aaagacgata attaacataa tacaatatag taattgatat aaataataca
     6961 tatattttaa ttaaccactt caataaaaat tacttagatt aaaactttat ttcttctggg
     7021 tatttccaag atttaaactc atcaacatct actacttcaa gttctttaaa ttgatttaat
     7081 actaaagact tatagtatat ttctgctaca tcttccacat atcttgattt taataatgct
     7141 tcggctaaat cattacctac agttgtcaac ccatgtcttt ctaataagca tgcatctgta
     7201 tctaacagta attttgaaac gatcttagct aattttaaag ttcctggtct ttcgtatgga
     7261 gcaatatcta cataaccgcc ataattaact gattcatata caattggtat aattggtttc
     7321 tttgccactg aaaatgctgt tgcatataaa gaatgagtat gcgatatagc atttacattt
     7381 tcccttgttt tatatatttc aatatgcatc aatacctcac tgcttggctt aatacctttc
     7441 tcaaattcta ttacatttcc atccaaatcc aatacacaaa tatgttcaac ttttaattct
     7501 tctcttccta tacctgatgg agttataagt atatatccag tattcttatc tctaatacta
     7561 aaattaccag tcttttcttt acataaacca taatgctctg ctttaattgc tatttccaca
     7621 actttacctt ttaaagactc tagcataact tacctccaga caatcatttt tgaccataat
     7681 atgcattttt tccatgtttt cttgaaaaat gcttattcat aagaacctta tccataagat
     7741 tatcaggact cattagctct gtataataag ccatctttgc gacttcttct aaaactactg
     7801 cattgtgtac agcctcattt gcatcttttc cccatgtaaa aggtccgtgg tcatttacaa
     7861 ttattcctgg acaatgaatt ggatttcttc ccataaattc ttcaataatt acatttccag
     7921 tttccttttc atattcattg caaatttctt ctctagtcat ttttctggta catggtatac
     7981 ttccataaaa ataatctgca tgagtagtac cacaagatgg tataggtttt cctatttgag
     8041 cccaaattgt tgcccaactt gaatgcgtat gtactattcc tcccaattct tcaaactctc
     8101 tatataaaac tagatgagtt ggagtatctg aagaaggtct tagtttgcca tcaactacat
     8161 ttccctctaa atcaactaca accatatctt ctacagtcat attactatac tctacaccac
     8221 ttggttttat cactaccaat cctttttctc tatctatgcc acttacattt ccccaagtat
     8281 aagtaattag ctttttttta ggtagttcta aatttgcttt taatacttct tcttttaaat
     8341 tttctaacac ttttcttcct cctatatttt attttaaaaa attatttcta ttttgtttaa
     8401 tgtcataatt atgaaattta attgttttag aatttttatt aaatttttat atttctacta
     8461 ggattttatt gaaattaatc tctctcttgc tcattttact taaaaagtca ccaacctcat
     8521 taagacctat tttatgtgaa atcataggtt taaaaataat atctcctttt cccataaaat
     8581 ccaatgttgc agtccatgct cttccaggat aagggcttgt atatgaattc caagagcctt
     8641 tcaaagtaag ttcaccacgt aatatacgct cagtagcgtc tgcactaagt ggtaattctg
     8701 tgtgtgatat acccacaaat actatatttc ctctcttttt tgctacaaat agagattgtt
     8761 cttgtgtaaa tcggctacca gcagtctcta ttacaacatc agcaccacca tttgttattg
     8821 tttttatttc tttaattaca tttacttctt ttgagttcag tatatagttt gctcctagaa
     8881 atttagaaag ttctaacttt tcatcaaaaa tatcaactgc tatgacctta gatgcaccaa
     8941 atacccttgc ccattgtata gaaaactgac ctattggacc acatcctaat acaaccacac
     9001 tatctccagc tttaatatta gactttgaaa tcccatgata agctatagtt gctggttcaa
     9061 ttccagcagc agtttcataa tccagtgtat ctggtagttt caagacatgt ttttctggaa
     9121 ctcttacata ctctgcaaat gctccattta ctcttgttcc aattatattg taatcatcac
     9181 acaagccaaa attaccttca ttacaataat cacattctcc acaaggtact aatggtgcaa
     9241 cggctactct atctcctaca ttaatatgct ttactttttc tccaattttg acaacttcac
     9301 cagaaaattc atgtcctaaa atcaatggat attttgtatt tccactcaaa ccacttacca
     9361 tagacctagg taaatctgaa ccacatattc caacatattt tacatttaca agcacttgtg
     9421 tatctgttat ttctggtata tctaccattt catatctaac atcacctaca ttatacaata
     9481 ctgatgctct cattttattt cccatataaa tatctccttt catgctatat atttctatat
     9541 agcaatatct atgccataca aaagataaat ggtttattca ggtaaatacc ttatatacaa
     9601 agtcttttgc caataggaat tacattttat aaaatcaaat tacattactg tataaatata
     9661 aaagagtatg ttttaaatga caggttatac agaaaactca actataaaaa tacaatgctt
     9721 tacaattaca aatattacct aaataaaaag aagtctatac ttcatttaaa tatttctcag
     9781 gtactatctg atacttatat aaaatcaatt ataaactcct ttaattattc ctatttcatt
     9841 tttataaact taaactgcta caggttcttc ttctacattt ttaagtgctt gtttttctag
     9901 ataatcaaga atacttgctt tgttctttct aaataatgcc cataaagcaa agtaaattcc
     9961 aactgcaata cctatataaa ttggatttgc acttagaaat gcaaagaaaa ctaatcccat
    10021 caaaggtttt cctagtatat taaaacttgt tattaacatt gctcctgcag gtatagctac
    10081 acctatattt gtagccatat ctgtaaataa tggtgctgta gatgtacaaa catataatcc
    10141 taatccaaac caaattatac ctgaaactag tacttttggt atattaccat tatgtatggc
    10201 aactaaacct tgaaccatat atggaattgc taataaatcc acaactggta atactttatt
    10261 gccaggaagt accatagcta ttacaagcat tattggaatt aatataagac ctgatattaa
    10321 agttgcaggt tcaccatacc caacagcatc atttactgct atgtaccact cacggtttcc
    10381 agctttttgc ataatctttc tagctgcttc tgttataggt gcaaatgctt gagcaaacat
    10441 gcttgctact tttgggaata ttgccataac tgcacttgta gatataccta ctttcattat
    10501 ttctccccaa gcttccatag tagttattct tgtcatatta cctaatatac ctataaacat
    10561 acctaaaaaa agacctaaag taattggttc acctaagaat cctaatttct tctctaattc
    10621 ttttggattt aattttattt tatttaatcc caatttatta tatatagggt ctgcaaatac
    10681 tgcaaacaca gaagcctcaa cattatgcat agctattatc gtacaattag gatatctata
    10741 gtaactagac catctctttg caactaactc tgatattaac aaactatata agtttaataa
    10801 aaccatacat gctataccta aaggaaaatt tcctgttact cctataacca ttgctcccca
    10861 taccatgtaa gaatagttat tccataaatc cgatggttga aacacgtctg tccattttat
    10921 caaaaataaa attgtttgta ataatatccc aagacccaaa tatatcatac ctgcacttgt
    10981 tgaaaatgca accaatgatg ttgcttgcca gccaacatca aaaactggta aatttactcc
    11041 tgtactctca accatcctgt tgataactgg tgttattatt ggtgtaaatg aatttaaaat
    11101 caatgtaaaa ccttgtaaag caactcctgc gtacacagca gaaagaaacg atttcttagt
    11161 agttacttta aatatctttg ctattatgaa tattataatt ggaactataa ttgcagaacc
    11221 aaatgtatcg attatagatt tcataaattc taacatcttt ttcctcctat ttataaatat
    11281 ttataagctt agtttaatat ctaaatgact atttttataa ttttttaatt tatgacaaca
    11341 tataaaatgt ttttttacaa atatttagtt aatattagct tattatagta tctaaatcat
    11401 tgatttaaat actataaatt cacatctcca aaacttactt atctatccct tcaataacag
    11461 tcaaaacttc ttcaaagaat gcctcttccc ctataccagt taggcaagca aatgcattta
    11521 tagttggtat tccataatcg cctgtttgaa gtggactagt aaatgttata aaatcaaatc
    11581 ttcctgattg cgctaaattt agtgcttctg ttggtctagc ttctgttgta gtaatagaaa
    11641 ttcccttatt ccctaatact tcttttaatt tacctgctac catagatgat gtaactgtcc
    11701 ctgaaccaca aactgataat acattaaatt gtttcataat aatttcctcc taatttttca
    11761 ctctaaattt ttattttata tatattaaac ctattaaaaa ataacactta ctttgattgt
    11821 ttaaatttta attttttatt tataaaattc tcatacatta tatttctata aagtccaata
    11881 atttagctac ttcttccttt gttgatgcgt tttttatatt ttttaataac tttacatttt
    11941 gaaaaactga cattaaatct tttaacagtt ttacttgtga atctgggttc tttactgcca
    12001 ataaaaatac aagttctaca ttaagcctat cttttgggtc tatcattgaa ttaaatttta
    12061 caggattttt caatatccct acagctacat tagattcatt tacatgcttt gaatctgtat
    12121 gtggaatagc aacacacatt tctccaatat cgagacctgt tggtaatgtc ttttctcttt
    12181 ccaagacagc atttatgtat gtgtctttta catattcttt tttacacatt atacttccta
    12241 attcttcaat aacactttca taatcattag attctaaacc taatgatatt aaatctacat
    12301 tcattactct gactcctctc aatttttttg ctatggctac agatgtttaa atttatcaaa
    12361 tataatcttt ttaaaagcat ctttattaaa gcacttattg gcattgttca taaattcttc
    12421 atcttttagt atctcaagaa cattcttaac aatctcttta tcattagcct gaaaaactgg
    12481 cataaatatg aaatttacat tgcctacacc ccaatcaata gggttcttta gtttgacaaa
    12541 aacaaacctg gtactattta cagtagaaga atctccatga ggcacaccta taaatccttt
    12601 agaatatgtt ggaagcatct cctctctatg taaaacagaa tctaaataat ctttttctac
    12661 atattcttta tttataagaa ttgaacatac atattctaat aaatcctttt taaaatatat
    12721 atctggttca aaaatcacta aatcctcatc aagcattctt tcatacgatt taattggtct
    12781 gtcatcttgt tgttttgatt ttgatagata tatatccaaa tttttgaaaa cttctttatt
    12841 gtagggtata aaatttatac ctggtacctt aggatttatt gtcccaacaa tagccaatat
    12901 attgcttgtc tcctttatat tttcaatttt acaaaataga ttttcatcca atgcactcat
    12961 ttgatagcat ttagtgttat catacttttc ttccaatgtt ttacttatat atttagcagt
    13021 tccttctcca gtaagacata atgttacaat tgcatttgat ttatctatgt gcttttctaa
    13081 ttcatagtta tatcccatcc tatcttttag taaagaaaaa aatatttcat caagttcttc
    13141 ctctcccata gaaacttttc tagctgcttc tagtgccatt aagaggtcta ctctatcaat
    13201 agttttagta tttatattgg ttctcttatt tactatttgc cctatgtttg taagtgagcc
    13261 aatatctacc aaaaacaata ttccttttcc ttggtctatt atttttgaca attctactgc
    13321 cttattgtat atatttattg gtttttcatc taaaggcata tctatagcca caggaaactt
    13381 tacacctaaa agttctttaa ctacatttac agtctctgta gctatacgtc catgagaaat
    13441 tattattaac cccactttgt cttttttcgc ttcatttttt agtgcagact ttatgtagag
    13501 cgttataaat ccaatttcat catctggaat cttaatacct attgattcct caatttttat
    13561 tgcaaaactt ttactaattt catattcttt tgaaaaatca atctttattt tttctaaatt
    13621 tacgtttatt atcttttgat ttagcttaat tctttttata gcttcttcta agtgtattgc
    13681 tagatatttg aacatatttt tatttacttc taaattaata tttttttcaa ctatatcatt
    13741 cataagttct tttaccagtt tgactaaact atcatttaca aaactattta aatcactcat
    13801 tgaaaaaata tcttcactac tatcgagatt aaactttaag tcagcaaatc tatttaaaat
    13861 aaaagtccat aaaatattct ctatatctat atcttcaata tctagggatt ttaggtcata
    13921 atatttcttt tcaattgttt tgtatatgtc ctctggtaat atatatttat cacttaaaag
    13981 atttcctttt actaatgctt cttctaagtt aaatggtata aatatagcat ttttcaagta
    14041 ttttcttatc tctgtatatt caacctcttg aaaggcagca tctttaaaag aatctttaag
    14101 ctttaaaact tcatttatat ctactaccac tatcgattca ctatcttcat ctttagaatt
    14161 tataaacttc ataaaagctc ttgcacaaag aacctgaatc atattttgta attgtcctat
    14221 atttccacta aactttttta gtgcaagtat ttcaatcaca tttttatcta caaatatttt
    14281 tgcgtttatt ctattacact cttgttgaaa gatattatat ataaggtcta ttttctcttt
    14341 tagtaatcta tcatgtaatg gtggcaaagt tattagcatt ggtattcttc ttctgaatgt
    14401 taataataag ttagtctcta cattctcagt agttgcccca atcaacataa tacttacttt
    14461 tctttcagca ttagtttcac ctaatctcct aaactttccc ctatctaaga tggaaaatag
    14521 tatttcttga ccttttggag gcaatctatg tatttcatcc aaaaataaaa ctccctcatc
    14581 agcttcttct acaagacctg gtgcatcata ttcagctcct gtaaatgcac cttttttata
    14641 tccaaataat aaagacaata ataattgtgg attatcacta tagtcagcac aattaaatac
    14701 aacaaaattg gaactttctt ttattatctt tttttgcttt gcaaactcat acatatgtct
    14761 agaaaataaa ctcttgccaa ctccactttc tccaacaatc aacgtcggta accctttagg
    14821 tgggtacaat atagcagatt tagcctgttc tacagcattt ctaagactcc ctttattacc
    14881 tatcagagtt tcaaatgggt cattcgattc ttcttcagtt tcctctacta cctccatttc
    14941 taaactttct ttaggtaaaa gttcctctac aactcttcta gatatattaa aaccttctgt
    15001 catcaattct cttgtaattt ctgatataga aatattctta ttcttttgta atattgtcga
    15061 aattgctgat tttagataag gatatcttct ttgccttgaa ttacttatat taagttcttt
    15121 tctcaaatta gttatattct ctctagttgt acttaaaaac tttgctattt gaacatctgt
    15181 taatggatct tttttatttt ctgtatttat gatgtttaca agtttatctc tcaactccat
    15241 gcttaataac tcctttcttg ttaaatatat aagcaactat catgccatac ttactttgat
    15301 atttttttct actcaaaccc tgtaagtaac tagatgccat aagtatttat acattttgat
    15361 aagcaattac attttgtata tttagtaatt tactaaatgt attagtcatt cataatctta
    15421 aatagtttaa ttctttgttt aaattgcaat gcaaaatact ttataaatat attattgaaa
    15481 aacttactca atcatatata atagtacgta tctactcaac aataaaaatt acaataaact
    15541 atgtttttaa ctctttctgt tttaa
//
LOCUS       DAMKOJ010000083        14978 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000083 DAMKOJ010000000
VERSION     DAMKOJ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14978
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.090"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            290..757
                     /locus_tag="PC592_002872"
     CDS             290..757
                     /locus_tag="PC592_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF4056820.1"
                     /translation="MKFGSVLIVVEDIEKSKRFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKGDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSMDEVAKRMDVTVEYIESVLD"
     gene            complement(849..1685)
                     /locus_tag="PC592_002873"
                     /pseudo
     CDS             complement(849..1685)
                     /locus_tag="PC592_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            2249..2902
                     /locus_tag="PC592_002874"
     CDS             2249..2902
                     /locus_tag="PC592_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDF4056821.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCILLNKQENNVCNIKA
                     IRNFSEIYSISRKSRYHSLLRLTEKGIIKKMGNTYEILNYDELHRLAFEVKEFLEDE"
     gene            complement(3042..4418)
                     /locus_tag="PC592_002875"
     CDS             complement(3042..4418)
                     /locus_tag="PC592_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4056822.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVGNIRKVTGLTCMLA
                     IILSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAISTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYFYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAVGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(4434..6347)
                     /locus_tag="PC592_002876"
     CDS             complement(4434..6347)
                     /locus_tag="PC592_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF4056823.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIDMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELKPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLELEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            6483..7115
                     /locus_tag="PC592_002877"
     CDS             6483..7115
                     /locus_tag="PC592_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDF4056824.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            7254..7793
                     /locus_tag="PC592_002878"
     CDS             7254..7793
                     /locus_tag="PC592_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF4056825.1"
                     /translation="MIFVEELWEKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGVDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(7959..8129)
                     /locus_tag="PC592_002879"
     CDS             complement(7959..8129)
                     /locus_tag="PC592_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4056826.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDASSCIDCGSC
                     AGACPVDAPQPE"
     gene            8414..9481
                     /locus_tag="PC592_002880"
     CDS             8414..9481
                     /locus_tag="PC592_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HDF4056827.1"
                     /translation="MKNKLIYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFKKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSVANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVVGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPHIIPTSITSSSSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNQ"
     gene            9651..11552
                     /gene="cooS"
                     /locus_tag="PC592_002881"
     CDS             9651..11552
                     /gene="cooS"
                     /locus_tag="PC592_002881"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF4056828.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVIKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFRLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            11545..12018
                     /locus_tag="PC592_002882"
     CDS             11545..12018
                     /locus_tag="PC592_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF4056829.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            11993..13219
                     /locus_tag="PC592_002883"
     CDS             11993..13219
                     /locus_tag="PC592_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF4056830.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENIYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVNWIAGKTVKGIDVNKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLREGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIILDDSKNVK
                     GVAFSNGEILDADMVIVATGVKPNADFLDETGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMAGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGLNDYKKFIFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFKIKENGEFCYSV"
     gene            complement(13372..14559)
                     /locus_tag="PC592_002884"
     CDS             complement(13372..14559)
                     /locus_tag="PC592_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF4056831.1"
                     /translation="MNITKNFLKDYLERFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            14832..14927
                     /locus_tag="PC592_002885"
                     /pseudo
     CDS             14832..14927
                     /locus_tag="PC592_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
BASE COUNT         5572 a         1818 c         2370 g         5218 t
ORIGIN      
        1 atatttcaat attctaaaat agtatttttg ttttagaagt tagataataa tataatctac
       61 aaaaacagga agttttttag ttaaatttat atgtatttta attttgaatc taaaagtgta
      121 gagatgtctg ttttttacaa gagtaaagca aatattatat gatataatca actcaactat
      181 ctaaataaga cttacaattt tcttgtttat atcatgtctt attgaaatat gtatagttta
      241 attttacttt tgtaatgaaa ataaaatatg tgtatatcaa ggaggaaata tgaagtttgg
      301 aagtgtttta atagtggttg aagatattga aaaatcaaaa aggttttatt atgatgtttt
      361 gggattaaag gtaatctgtg attttggaga aaatgttgta ttagaaggga atatatcatt
      421 acaagaaaaa aagctttggt tagagtttat taataagggt gacagtgaag ttaagttcaa
      481 tggaaatgat gctgagttat attttgagga agataatttt gatacttttg ttgaaagatt
      541 gagtacaatg aaagatatag attatgttca tctagctata gagcataggt ggggtcaaag
      601 agcaattaga ttttatgatt tagatgggca tattattgag gttggagaaa ctatgtcatc
      661 tgtgtgtaga cgttttttag atagtggtct ttcaatggat gaggtagcta aaagaatgga
      721 tgtaactgtt gaatatattg aatcagtttt agactagatg gattatgcta aaataaaact
      781 gaggtgaggg ctgtaagtaa acttgtgtga aaataaattt acttacagtt tttgtttttg
      841 taaaatatat cattcttact atattttaat tttaatgatg ggttttatta cttgaagacc
      901 ttaagtttgg aggtaagtct ttctctaata caatatcttc acacataata tttaaataag
      961 atgtaacatt ttgaagttct cttatattat ccttccacgt ataattttgt ataagttttt
     1021 ttgcttctgg tgtgattact aatttcttat taattaaatc ttccataata attaatatat
     1081 cttctttctc ttacaagagg tatatttatt ggaattgtat ttaaacgata atataaattc
     1141 tctctaaaat ggctattatc aataatttgt tccaaattct tatttgtagc agatataatt
     1201 ctaacaccta tattaattat attgtgagaa ccaacaggca ttatctgttt ttcttgaaga
     1261 actttaagta attttgtttg taattctaag ggcatatagc ctatttcatc taagaatatt
     1321 attccattat tagcaggcta aaataatcct tattttccat cttttagacc tccagtaaaa
     1381 gttcttttgt catatccgaa tatctcattt tctaataaat tttcaggaac agttgtacaa
     1441 tttactgcta taaagggttg attttttcta tttgagttgt tatgtataga ctgagctatg
     1501 agttttttac cggttctact ttcacctctg acaagtatgc ttaagtcaga tttagaaacc
     1561 ttcttagtta aatctatata ttcgagcatt ttggggctag ttgtttttat atccttaaat
     1621 gtatattttg ctatttgtcc tttttctttt aattttttag tgagattttg ttctaaattt
     1681 tttaatttat ataatctcca aaaactaatt taaaattatt ttctaaaaaa tctgttaaat
     1741 cttttctatt atcatttata agaagcactg atttttttat tgatttctcc ttatataata
     1801 aatagtttcc aacaaaatag ttgtataaag caatctaatt ttgataattt aaatttatca
     1861 aataaaaaag aaagtgtcta taatgacctt acaaaagttg cattaagaca ctttccttct
     1921 tataattaaa tcttgtcacc aaatccccct aattgttgcc taaaatctaa actgtatgta
     1981 tatttttcat ttctattcga ttaaattata atatacaccc aaaaaaattt attttaataa
     2041 attctattga taatataatt ttataaatat agaattgtat taaaataaat tatatatgaa
     2101 aatatatatg tataagttta ttctgcgtga gtagaatgaa tttgtcaagt ttaatttaac
     2161 tataatcata tcttttatta aaaataatat aaattaaaac atataaataa aatattttat
     2221 acaatatatt gtaaaggagg taactttgat gaaagcagaa aaaacaagta tatatccaat
     2281 tattaaaaat aatttaaaca aaatatcaat tgttgaatat aaaaagggtc aaagatttgt
     2341 agcatcagat aaagacttgc aagaagtatt ctttataata gagggagttg cattagtgga
     2401 gtgcactact agaggaggga ataaatttct tgttgacatt gtacctgaaa atgaatttat
     2461 aggcaaaatc agttatatat atgaacataa tttgaaatgt gatatatttg caaaaaccaa
     2521 tataaaatta tttcgatttg aaaaaaatgt atttgaagag ttttatctta aaccagattt
     2581 tattgcacta tttcacagaa aatgtacaag aagaatatat gaattatata aaactagaat
     2641 ggtaagagaa ctattttctt gtacagaggt tattgcctat tgtatattat taaataaaca
     2701 agaaaataat gtctgcaata taaaagccat tcgtaatttc agtgaaatct attcaattag
     2761 tagaaaaagt agataccatt ctctgttgag gttaactgaa aaaggtataa taaaaaaaat
     2821 gggtaataca tatgaaattt taaattatga tgaattacat agattggcat ttgaagtaaa
     2881 agagtttttg gaggatgaat aaagattatt acttaatcaa aataaggtat aataatttct
     2941 gtaaaaaata gaaatagtct cactgaaaat caaaaatact ttagttgttt tcaatgagac
     3001 tgtttagaaa tattgtatac ttacaatgta tagtatagtt attagtcaat ttcctttact
     3061 atgttaatag cccatttttt agataatgct ctaggaacac caaatataaa cttaacaact
     3121 tcttcactgt aagtgagtag aacaagtaca aatataggtg cacctttaaa tgcagctata
     3181 aaagttagag gaatagaagc tagccacata catcctaatt ctaaaaatag agcatattta
     3241 gtatctcctc cacttcttaa aataccaatt ataaccaatg tattaaaaga tttgagagcc
     3301 attagtattc ccattataaa gaatatctta gttatatcag aagctaagct atcagaaaca
     3361 ctaaacattt ttaataataa tggtatattt aaaattaaaa taattccaag tattaaacca
     3421 gctgaaaata caagtataga aaacttttta gcatattcaa tggctctttt aatatggtca
     3481 gctccaagtt catttccaag cataatagat gcaccagatg cgatacatac agcagtcatt
     3541 atgaagaaat tgcctgtact ggttgctatc tggctggctg ctatagcaga agtaccagct
     3601 cttgcatatg caacagaata cagcacagtt ccaactgccc atacagagtc atttacaaat
     3661 ataggaaagc tttttgatga aaaagatttt ataaaaattt tatcaatagc ttttagattt
     3721 ttcagaccaa attttaatat atagtctttt ttataaaagt aaacataagt aatcattaaa
     3781 attaattcac atattctagc aataacagta gctagagcag caccttttac acccagtgca
     3841 ggaagaccga agttaccaaa gataaatcca taatttaaaa taacatttgt tacaagtgca
     3901 aatgcactac aaatcatacc taacttagga tttctaacac ctcttgaacc agtactaaat
     3961 acagtactta tagcaattaa tggataacta aatactgcaa tactaaagta atctatacaa
     4021 agttttacaa cttcagaatc atacgaaaat atgtgtataa ttggctttgg tgttagtaaa
     4081 gcaggaataa caaatacaaa acttaaaata atggctaaca tacaagtaag acctgtaact
     4141 tttcttatat tgccaacatc cttctttcca taaaactgtg aaataaaaac tccagcacct
     4201 cctgtgatgc cagataagga catattaaaa agaaagaaaa attggtttgc aactccaact
     4261 gaagctacag atgtttctcc taaactactt atcataattg tatctattac atttacagaa
     4321 gtagaaatta aattctgtat aataataggt atacataaag atagaagtat tttataaaat
     4381 cttttatttt cgtcttttaa agaaaatagt tcttgcaaat aatcctctcc tttttacata
     4441 aattcttccc actcatcata tagagaggca aggttatttt ctaaattaat tttttcttga
     4501 ctaacttctt tagccttatc tggattagag tatacttctt cttgacataa aagtatatct
     4561 aatttttcaa tttcaagctc taacttttca atttcttttt ctatattttg tctttttatt
     4621 ctatttttct tttctatttc tctttgttct ctctcttttc ttttttcatc ttttatttga
     4681 gttctagttt tttcttcttt ttcttctata atactcattt cttggatttg ccttttttta
     4741 tctatataat aatcataatt tcctagatat tcagtaattc cattttcatc taaaactaaa
     4801 attttatcaa caacagtatt tagaaagtat ctatcatgtg atattgtaaa tatagttcca
     4861 tcataattag ttaatgcctc ttcaaggact tccttagaat caatatctag gtgattagta
     4921 ggctcatcta ataataataa gtttgcattt gatagtataa gtttaagtat tgcaactcta
     4981 gctctttctc caccgctcaa tgtagaaatt ttcttaaaaa cttcttcatc tacaaataaa
     5041 aatgctccta acatatttct caaagtagtt tgagtaagat gagtattatt ttcccaaatt
     5101 tcatcaatta ttgtattatc taaattaaga gttttttgtt cctgatggaa gtaggaaaca
     5161 tggacattag ttccaaattt aatattgcca ctaagaggtt tcagttcatt agttattatt
     5221 ttaaataatg tagatttacc aacaccattt gcacctataa gagcaacttt ttcccctcta
     5281 tatatatcta aatccaagtc tttaaaaagt attctttctc cataacccat agatacatct
     5341 ctaatttgaa gaacatcatt accactctgg acagaaggcg taaattgtat acgagctttt
     5401 tttctataag cttctggttt atctaaaacg tctaccttgt ctaatgcttt ttctttactt
     5461 cttgcacgct ttaggtgttt ttctctacca taagctttta gtctttcaat tgattcttct
     5521 tgctttttta tttctttttg ttggtcttca aatttcttaa gttctagttc tttttctatt
     5581 ttagataact caacaaattt agagtagtta ccattatata ctttaagttt tttgttatga
     5641 acttcaaaaa ttctatttac agattggtct aagaaatatc tatcatgaga tattaacatg
     5701 acagtccctt tatattgttt taaaaatact tctaaccatt ctattgcttc agagtctaag
     5761 tggttagtag gttcatcaag taacaataga gttggtttct taagaagtaa ttttcctaaa
     5821 agaactctag ttttttcacc accagaaagt atacttattg gcttatccat atcattgtca
     5881 ctaaatccta atccttttag aactcctttg gcttcagact tatatccata tccatttaaa
     5941 tctgaaaata attccagttt atgtgaatat tcatccataa ttttttctat aattggagaa
     6001 tttgtttttg tactttcttc agatatttta acctccaatt ctcttaaata ggactccata
     6061 tctatcaaat ttttaaaaac ttctagtact tcttctaaaa tagtattatc cgaataaaaa
     6121 ttggtatttt gttctaaata tccgatttca caatctttag aagtgtaaat atctccacta
     6181 tcatatccat aaattcctga aattatttta aataaagtgg tttttccagt accattaaca
     6241 ccgattatac caattttatc gccttcattt actgtaaaac taatattttc taatatagaa
     6301 tctataccaa aacttttatt taagttatta catgacaaaa caatcataaa tttctacctc
     6361 cttgaactat ctaaaattat aatgttttga tataatataa tcaaggttat atgtattagt
     6421 tttgaaaaag aaatatttta ttgtgaatca aacaaaaaag aggacacttt taggaggtga
     6481 agatgttggg aaataaaaat atatcaatgg cagttataag aaggctacca aaatatcata
     6541 gatatcttgg agacttatta gatagggata tacaaagaat atcttctaaa gaattgagtg
     6601 atataatagg gtttaccgct tctcaaataa gacaagattt aaacaacttt ggtggatttg
     6661 gacaacaagg gtatggttat aatgtagaag ctcttcatac tgagataggt aaaattcttg
     6721 ggttggatcg accatataac gcagttcttg taggagcagg taacttagga caagctatag
     6781 ccaattatgc aggatttaga aaagctggat tcgagataaa agctttattt gatgcaaatc
     6841 ctagaatgat aggtttaaag ataagagagt ttgaagtatt agattcagat actttagaag
     6901 actttataaa aaacaataat atagatattg ctgtattatg tatacctaaa aatggagcac
     6961 aagaagttat taatagagtt gtaaaagctg gaatcaaagg tgtatggaat tttgcacctt
     7021 tagatttaga agttccgaaa ggtgttatag ttgaaaatgt aaacttaaca gaaagtttat
     7081 ttactttatc gtatttaatg aaagaaggaa agtagacaac ttaaacatat taataatgag
     7141 tagttgtgaa gagtattgag aaagtcagaa gatttaatat taaatcatct ggctttttga
     7201 aatattagga taaaaattta aataatatat gtaaataaat agtattaagg agagtgattt
     7261 ttgtggagga attatgggaa aaagcaattg aatttcatgg tcatgaatgt ccaggtttag
     7321 ctataggatt taaagcagca cttgcagcaa gagaatattt aggatgtaaa caatcaggag
     7381 atgaggaaat tgtgtgtatt tctgaaaatg atgcttgtgg agtagatggc atacaagttg
     7441 tattaagttg cacaatgggt aaaggaaatt tactacttag gatgactgga aagtctgtat
     7501 atcatttctt taatagagaa aatgggaaat ctataagaat atatgtaaag tcaaaaccat
     7561 ttgagatgga tagagaagga tataagaaat atttattaga aagtgatttt gaagaaatat
     7621 ttgagattac agatactaag ttaagacttc ctgaaaaagc aagaatattt aaatctctta
     7681 aatgtgaggt gtgtggtgaa tttgcatctg aacaatatat aaggattgaa gaaggaaaga
     7741 aagtatgtct tgattgcttt aataaatatg aaagatttta tgaggagtat taaaattata
     7801 aattaaaagt attagatatg cgctaacaat attttaagat gaattaggta gtaactataa
     7861 taaaatatat aaataatatt acttgaatca tacataatta aaaagaggct gattagtatt
     7921 tagaaaataa aatcagtctc tttatgaata acgaattatt attctggttg aggtgcatct
     7981 acaggacaag ctcctgcaca agaaccacag tctatacaag aactagcatc tataacatat
     8041 gcgtcgtctc cagctgatat acagctaaca gggcattcag cctcacaagc accacagctt
     8101 atacaagcgt cagtaatttt atatgccatt ttgaaatcct cccttttata tgtattgtaa
     8161 ttcaataaca ttataacaaa tattgttgaa tataacaatt aaattaattc tacaacaaaa
     8221 actttattat gatattcttg ttttagagtt ttacaataaa gtttaatctg cttatatttt
     8281 tatttatttt aaagagattt attttaaaaa taaaattaaa tttaaaaagt tatgtattga
     8341 ttatatttga aaatgttata ctctaaaaaa gtatatttta ttttaaaatt tattaataca
     8401 aaggagattt actatgaaga ataaattaat ttacatatgt atcatgagtc tacttctatt
     8461 tgtagtagga tgttctaata atccaaacaa agaaagtact attaaaaaag actctaagaa
     8521 taaccaaagc caagttaaag aagaaaaaag agaacctgtg aaaaaagata taactataag
     8581 tttcgctggt gatgtaacta tgggaaacta taaaggctcg tcatattatg gtagttttga
     8641 ccatgaattt aaaagacaag gagaagatta taattatttt cttaaaaatg taaaacctgt
     8701 atttaaaaaa gacgacttaa cagtggttaa tttagaaggt ccacttacta cagcgtcaaa
     8761 tgcaaaagaa aaaaaatttg catttaaagg aaagcctgga tatgtaaata ttttaaaatc
     8821 tggaagtgta gaggcagtga gtgttgcaaa taatcattca gaagattatt ttgaagaagg
     8881 aatgaaagat acacagttta tattggatga gaataaaata aattattttg gattagggaa
     8941 agatgctgtt gtagatgtca aaggaattaa agtgggtcta ttagggtata atggcttatc
     9001 aactgagtat aatgaaaaaa acttaaaaca aatggaagat gatattaagt ccttaaaaaa
     9061 gaaatctgat gttgttgtag tgtactttca ttgggggata gaattagatt attatccaga
     9121 taaaaaacaa aaagattttg ctcattatgc aatagacaag ggagctgatt tagttgtggg
     9181 gtctcaccca catgtgattc aaggaataga aaagtacaaa aataagtata tagcttatag
     9241 tttagggaat ttttgttttg gagggaacaa gaatccttct gatacagata gttatatata
     9301 tcaacaaact tttacttttt cagataataa attaacttca atcaaagagc cacatataat
     9361 accaacatca ataacatcta gtagttctag aaataattat caaccaaaag tattggatgg
     9421 aagtgagaaa gatagagttt tgaataaact cgaaaaaata agtaaagatt taaatcaata
     9481 aaatataaaa aaaaataaat atatatattt attttaataa tttatattct gtttaggata
     9541 tgggaaatcg tggtattaaa taagtagatt ttaatagtta aattatagtc aattataata
     9601 aagctattta atctactttt ttaatataaa aatataaggg ggaatttgta atggcttgta
     9661 acacttgtaa aatgtgcgaa agtgcagaca agaaattaga aagttttgta gcttcaaagg
     9721 atgttgaaac agcatttcat agaacagaag atcagaaagt taagtgtggt tttggacttc
     9781 agggggtttg ttgtagactc tgttcaaatg gaccatgtag agtaactcct aaatcaccaa
     9841 gaggtatatg tggagcagat gcagatacta tagtagcaag aaacttttta agagcagtag
     9901 catcaggagc agcttgttat ttacatgtgg tagaaaatac agctaagaat ttaaaaaatg
     9961 ttggaataac taaaggtgtt attaaaggag aaaaaacatt aaatcaatta gcagagatgt
    10021 ttgggataga aagtgatgaa aagtatgata aatgtataaa ggttgcagac aaagttatca
    10081 acgatttgta taaatcgaga gatgataaaa tggaattagt agaaaaaata gcttatgcac
    10141 ctagagtgaa aaagtggaaa gagttaggta taatgcctgg tggtgcaaag tcagaagttt
    10201 ttgatgcaat agtaaaatca tcaacaaatt taaatagtga cccagtagac atgctagtta
    10261 attgtttgaa cttaggtata tcaacaggat tatatggtct tacactaact aatcttttaa
    10321 atgatgttat gttgggagaa ccagttataa gaatggctcc tgtaggattt aatgtaatag
    10381 acccagacta cataaatata atgataacag gtcatcaaca ttcaacattt gcaaatttcc
    10441 aagatagatt aaaagatgaa gatgttataa aattagctca atctgttggt gcaaaaggat
    10501 ttaggctagt aggatgtaca tgcgttggtc aagatttaca attaagagga gaacattatc
    10561 aagaagtatt tgctggacat gcaggtaaca attttacaag tgaggctgtt ttatcaactg
    10621 gagcaataga tatagttctt tcagaattta actgtactat accagggctt gaaccaatag
    10681 cagataaata taaagtaaaa atggtttgtt tagatgatgt tgctaaaaaa gcgaatgcag
    10741 aatacatagg tttagacaga agtaaattag atgaacttag taacacttta atagaaaaag
    10801 cattggagtc ttataaggag agaagaggaa gtattgaaat agatatacca aaagaccatg
    10861 gatttgaaca atctttgact ggtgtaagtg aaaagaactt gaaagcgttt ttaggagatt
    10921 catggaaacc tcttattaat ttaattgcag aaggaaaaat taaaggtgtt gcagctgttg
    10981 tgggatgttc aaatatgaca gcaggaggac atgatgtaaa tactgttgag cttactaaag
    11041 aattgattaa aaaagatata atagtactat ctgcaggatg ttctactgga ggattagaaa
    11101 atgttggtct tatgtcacct ggagcagaag aattggctgg ggaaaactta aaagaagtat
    11161 gtaagacttt aggaatacca ccagtattaa actttggacc atgtctagct ataggaagac
    11221 tagaaatagt agcaacagaa ttagcagctg agcttggaat tgacttacca caattaccac
    11281 tagtgctttc agctccacaa tggttggaag aacaagcatt agctgatgga gcttttggtc
    11341 ttgctcttgg tttacctctt catttagctt tacctccatt tataacagga ggaaaattag
    11401 taacagaagt attaacagaa aaattaaagg acttaacagg aggacatgtt atagtgaatc
    11461 cagaccctaa atcttcagct aatcaattag aagaaataat aatagacaga agaaaaaatt
    11521 tagggttaaa ggatgtggaa tgtaatgcat agaattttta taaataaaga tttatgtaca
    11581 ggatgtaaga gctgtgtact agcatgtatg ctaaaacaca ataaagatta tgacatgtac
    11641 actcttgatt tagaaaatat agataatgat agtagagggc atatagaatt agatagtaaa
    11701 cataataatc cagttccaat tctttgtaga cactgtgatg aacctgaatg tgtattagca
    11761 tgtatgagtg gtgcaatgca taaagatagt gaaagtggaa tcgtttcata tgatgaagag
    11821 aaatgtggtt catgttatat gtgtgtaatg tcttgtccat atggattatt aaagccagat
    11881 gatagaagca agcaaaacat acttaaatgt gatttatgta aagatgagga gtatcctaga
    11941 tgtgtagcta attgtccaag tggagcaatt gaattacaga aggaggaaaa tgatgaatta
    12001 tgtagtgtta ggggctagtg cggctggtat aaatgcagta aaaacattaa gagaattaga
    12061 taaagattca aatatagtag taatttctaa agatgaaaac atatactcaa gatgtatgtt
    12121 gcatcatgtt atatctgaac acagaacttt aaaacaaata aattttgttg atgaagattt
    12181 tatggagcaa aataatgtaa attggattgc aggcaagact gttaaaggta tagacgtaaa
    12241 taaaaaagta gttcagacag aagacattac tgtaaattat gataaacttt taatagctac
    12301 aggtgcatct tctgctattc ctcctataaa aaatttaaga gaaggaaatt ttgtatattc
    12361 tgtgagaaac atagatgaca tttataaaat aaaagaaaaa gcacaaaatt ctaaaaatgt
    12421 agttataata ggtgctggtc tagttggtat agatgcacta gtgggattat ttaaatatga
    12481 gcagttgaat atttctgtag cttttatgga aaagtacatt ttagatagac aattggatga
    12541 atatacagca tcagtgtatg aaaataagtt caaagaaaaa ggtgtaaaat tttatccaag
    12601 tgcatcaata caagaaatca tattggatga cagtaaaaat gttaaaggtg ttgcattttc
    12661 aaatggagaa attttagatg cagacatggt aattgtagct acaggggtta aaccaaatgc
    12721 tgacttttta gatgaaacag gaatagaata tgatagaggt ataataatag atgatatgtg
    12781 tcaaacaaca caaaaagaca tatatgcagc aggagatgtt gtaggtaaaa atgctatttg
    12841 gcctctagca gtaaagcaag gaattgtagc tgcatataat atggctggaa aagataagaa
    12901 gatagaagat gaatttgctt ttaaaaatag tatgaatttc atggatatac caactatttc
    12961 tataggaatg aatacacctg tagatgatag ctataaagta ttaaccagac atggacttaa
    13021 tgattataaa aagtttattt ttaaagataa tgtaatctat ggagcagtta tacaaggaga
    13081 tatttcatat gtaggtgtat taacttattt aataaaaaat aaagttgaaa tatatgattt
    13141 agaaaacagg atatttgatg tatgttatgc agactttttt aagataaaag aaaatggaga
    13201 attttgttat agcgtataat atatatggag taaggtttat aaatacagta aatcaataaa
    13261 tacagtaaat caataaatag agttattcta aaataagaaa aatgagaaat cttatttaga
    13321 aatagctcta tttttgtaat taagtttaaa ttatatttaa tttgtaaaat attattttga
    13381 acaattatac atatattctc tagttagagg taaatcattt tttatgcctt tagtgaaaag
    13441 tatttgatgt atatctataa taccagtatt gaaagcagcg gcacaagaac aaaggtataa
    13501 atcccacatt cttataaact tatcatcaaa catttcttta atctttggaa gattctcaga
    13561 gaagtttttt tgccagtata gtaaagtttt tacataatgt aatcttagac tttccacatc
    13621 tatagtatga tacttgtaat cactacaaat atgtatcatt tctcttagac taggaataac
    13681 tcctcctggg aaaatatatt tttttatcca agggtctcca taagattcct gcaacccact
    13741 tatatagtga agtaaaaata atccgccatc ttttaaaaca gcgtttacgt ttttaatgaa
    13801 aagttcatag ttttctctac caacatgttc aagcatccca acgcttacaa ccctatcaaa
    13861 cataaggtct gattttttta attctctgta gtccataagt cttacctcaa ggtagtcttg
    13921 aaggttctct tctttgattc ttgcgttaaa ttccttaaat tgctcttcgc taagtgtaat
    13981 tccaacacca tgaattttat atttttttgc agcttctatt agtaaaaatc cccaaccaca
    14041 accaatatcg agaagactca taccttcctc tagatttagc ttagttaata tgtggtgaac
    14101 tttattgact tgtgcatcat aaagagtatc attatcattt ctgaagtatg cacaagaata
    14161 actaagtgtc ttatctagcc ataagctata aaaatcgtta ccaatatcat agtgggcatg
    14221 tatttctttt ttctgatgtc tcattgaatt tgatgagtgt aatagatgtt ttacagctga
    14281 attatcaata ttgaatttgt ctatttgttt taaaagtaga tttaaagtta agaataaatc
    14341 tccctcaact tcaatatctc tatttatgta ggcttctcca agtgctaaag atgtactttt
    14401 taatagttca gacttgctaa tatcgttatt tactataact ttgaactgag gggagccttc
    14461 tccaattaga aattcttcct catctttaag cctaactaga aatggtgttt caccaaatct
    14521 ctctaaatag tcttttaaaa aattttttgt aatattcata ttaccagctc cttctaatgt
    14581 aaatccagta agtttccctg cttaaaatat attatagtcc tttttttaaa aaagtaaaat
    14641 tttttcaata aattttttat ttaaaggaaa tttatttttt ataaagaaat ttcatgttgt
    14701 agtatatttt ttgcctataa attttggtac tggatataat attaaactgt taatgatata
    14761 ataaatttaa tctataaagt aaataaaatt ttgtaataaa tagttaaaac tattttataa
    14821 ggagatatag gatggaagta tatgctttgg ttgggtcaag tggcacagga aagagcttta
    14881 aagctttaga gttcgcgtat gaaaatgata tagaatatat aattgattaa aaaatagcta
    14941 cgcacactcg tgactttagt catgaattag tagctaaa
//
LOCUS       DAMKOJ010000084        14581 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.091, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000084 DAMKOJ010000000
VERSION     DAMKOJ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14581
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.091"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(101..760)
                     /gene="deoC"
                     /locus_tag="PC592_002886"
     CDS             complement(101..760)
                     /gene="deoC"
                     /locus_tag="PC592_002886"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDF4056832.1"
                     /translation="MKHILQTVDHTMLKATTTLKDIKTLCDEAVRMNVASVCIPPSYV
                     KSATEYLNGRVNICTVIGFPLGYQTTKVKVFEAKDAIENGAVEIDMVVNISDIKNEEY
                     EKIENEIKEIKSVIGDKVLKVIIETCYLNEYEKIKMCEIVTNSGADFIKTSTGMGTNG
                     ATLEDIKLMKKHIGEGVKIKAAGGIKSISDAEKFIEAGAQRLGTSSICKILNGEKPME
                     Y"
     gene            complement(787..2331)
                     /gene="murJ"
                     /locus_tag="PC592_002887"
     CDS             complement(787..2331)
                     /gene="murJ"
                     /locus_tag="PC592_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF4056833.1"
                     /translation="MSRVARAAFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDINSKKGEKEALKFLNNVLNIIVGICIIVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTRILIIGIIFIGITSVMSAFLQIKENFIVVGF
                     GSIPYNIVIIISIVLSTVLGPYVLPVGAVVAMVVQLFFYLFFVNKTKYKYLFYLDFKD
                     ESLIKLLALLSPVFIGVAVNQVNSLVDTTLASTLIKGSIPALTYADRLNGFVTGTFTA
                     SIVSVMYPTLSKLSAENNQKKFTISVKSSVNMIIISMIPISVASIVFAKPVVRIIFER
                     GAFDSRATQMTATALVFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIVSVGVNILL
                     DLALIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIRAIFKSLVSSCVM
                     SFIAYFIYKFIFGILGLGTLNELISLTISVVIGFSVYTLLMILFKVEEVDMILNIAKR
                     KLHLKK"
     gene            complement(2626..3390)
                     /locus_tag="PC592_002888"
     CDS             complement(2626..3390)
                     /locus_tag="PC592_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056834.1"
                     /translation="MKNINKECLIKLLTVMVVLIQIIYLLWKKEIVYYIHPRMIPYLV
                     ISICILLFIALSYIMILTKPKHIYQYGSTKYIILSFLITTLLISYSGLNIDKEKTKVE
                     KYKGKEKYQDKIYEKEEFLDRTLEERIYDEKFDVFDTEIYDFLNLLYTKQSVLKGKEV
                     TYVVFVHYDDSLEKNQFIASRSIMVCCAADMISSGPIVNMNQPPKWKEGEWILLTGKI
                     EYKEQKNSSNKTAFLNYIDAKPIEKPLEEVVYPNFG"
     gene            complement(3531..5087)
                     /locus_tag="PC592_002889"
     CDS             complement(3531..5087)
                     /locus_tag="PC592_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF4056835.1"
                     /translation="MSTRIDIVAGFLESGKTKFINEYLRNKQYDDKDNILLIVLEEGF
                     TEYSIPFSSKNYIKIERFKDINCLTKEYLKKCSNLYNYILIEYNGTWNIEEFLDIKLP
                     YSCYLGKIYCLVNADTFDVYFRNIDSMVEQIINSDEFYISGSNSIEKTEKITSYIRAL
                     QPSADIFYIDESGNYKKIFPLSLKLKNLIYRIIKFVIVILFFLLLLGVKIQIIKVQDI
                     NDFNRMFFGIILQAIPFLLIGIVLSSCIQFLVSEEKFIYFASRHKVLSYPIFLFMGCI
                     LPLCDCAMVPITEKFIQKGLKVSHAMTFFCISSSINPIVILATIYAFPENNKVIWIRI
                     LVSIMLSALVGISFYFVEKNKNFSPYKKNKIPLFNNIEYEITKITKKGKKFRFLALGI
                     HIGNEFLRIMMFIIIGAFISTIAQILKMNPAFSGYFTNDYAFLYMFFASVFLSICASS
                     NAFIAKGFTNSLPLMSVIPFMVFGPLLDIKNLIVMSSRFSKKFMTIFIIILLVCYIMY
                     FVFFNMEIKL"
     gene            complement(5088..6017)
                     /locus_tag="PC592_002890"
     CDS             complement(5088..6017)
                     /locus_tag="PC592_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein P47K"
                     /protein_id="HDF4056836.1"
                     /translation="MIKIDIISGFLGSGKTTFIKKLLSAYYKDKKVVLIENEYGEVGV
                     DGLLFKNENIQVRELYSGCICCSLNTDFTKSLKEVIELFKPDTVIVEPSGVGKLSEVI
                     QNCIPLVKQNLVSINHKFTIVDVMKYSVYLKNFKEFYDDQIKYCDAVLLSRVDVCDEI
                     KVREVISSIQNKYHKKYIVSLEQNLLDETIVNYIMSTKSVVHSENDMHCNCHHNHVVH
                     NADDVFSSWGIKLEKSYKYEYIKEILEQFNSGSFGNIIRAKGIFKCEDGLFYEFSFVP
                     DEIKVIPCNYISSGCICVVGFKPNKEKLERAFV"
     gene            complement(6073..6861)
                     /locus_tag="PC592_002891"
     CDS             complement(6073..6861)
                     /locus_tag="PC592_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDF4056837.1"
                     /translation="MLSYGFMQRALFVGLCVSIAIPCVGLILVLRKFSMLGDALSHTA
                     LAGVCFGLVVGISPTIGAIMSCIIASFSVSIIGKRMKHNEEIAIAVILSLGVGISGIL
                     SNYIKSSVNINSFLFGSIISISGREFALVIALTILILIIFFKYYYEFMFYAFNEKEAQ
                     KHYVNTRKIDILFTILIGLTISISARVVGALIISSLLVLPVACGLILGKSYKSTLLIA
                     IFLSMLFVLSGLTISYYIGLSPGGAIVILGSITLMIILLYKKRV"
     gene            complement(6854..7498)
                     /locus_tag="PC592_002892"
     CDS             complement(6854..7498)
                     /locus_tag="PC592_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4056838.1"
                     /translation="MKNIVEIKDGAFSYTDCNVFKSVNVNINKNELVGVYGENGSGKS
                     TLFKIITKEVKLQSGEIFTFDSLTTSFLGQNDRVMAEGSPLTLMEFLLMYQHKEKSKL
                     FKNKKNVMMLLRKYNMEHYAKKQLKSLSGGQLQKSMILKSIMNHPDIILFDEPLNALD
                     EVNKISVMDMIMDLHNNGHTILLILHDYEQLKKIADKILICENHTIKCEVLNYA"
     gene            complement(7501..8403)
                     /locus_tag="PC592_002893"
     CDS             complement(7501..8403)
                     /locus_tag="PC592_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HDF4056839.1"
                     /translation="MKRFVLLFCCSLLLLTGCSFKDVKKTSSNKKLSVYTSFYPMYDF
                     AKKIGGTKVDVKNMTPAGIEPHDFEPTTNDIKGLSNADMFIYNGDNMEHWVNDVIQSL
                     DNRNILIVKASDGIDLMKGEKSSDSMDPHTWLSIRNAKKELEKIKNAFCKKDPDNATY
                     YEKNYYKYASEFDALDSQYKKELLPYKGRSIVVAHQAFGYLCKDYNLKQIAIEGLSPD
                     SEPSPARMAEIIKSAKKNKIKVIFYEELVNPKVAETIAKETGSETKVLNTLEELSDKK
                     IKEGEDYISVMKTNLQNLVYALSK"
     gene            8538..8969
                     /locus_tag="PC592_002894"
     CDS             8538..8969
                     /locus_tag="PC592_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF4056840.1"
                     /translation="MVVLYMNNYLKKHNLKSTEKREAVIKVLENSNVPMTIESIHEKA
                     NTIVEMNLSTIYRTITTLCEKNITVLVAIHDGKSYYQLNKHRHEHVLICKECKDIIII
                     DECPLHELEHKLEDETGFDIIEHKLEFIGICPKCKRTNSRT"
     gene            complement(9444..10328)
                     /locus_tag="PC592_002895"
     CDS             complement(9444..10328)
                     /locus_tag="PC592_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4056841.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVMHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGRVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(10619..11095)
                     /locus_tag="PC592_002896"
     CDS             complement(10619..11095)
                     /locus_tag="PC592_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDF4056842.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            11361..12536
                     /locus_tag="PC592_002897"
     CDS             11361..12536
                     /locus_tag="PC592_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HDF4056843.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQDYDYNSMKNTLDNVSDNVNEQLKKLGESVKSSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     SDSDTNNSKNNTSTNNENKDNSQTNENDTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(12617..13420)
                     /gene="proC"
                     /locus_tag="PC592_002898"
     CDS             complement(12617..13420)
                     /gene="proC"
                     /locus_tag="PC592_002898"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF4056844.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQETLDRI
                     YANFGINTTKDSKEVTRSSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIVGDDKKIVRTMPNTPALVNEAMSSLSINKNINDEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(13460..14044)
                     /locus_tag="PC592_002899"
     CDS             complement(13460..14044)
                     /locus_tag="PC592_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4056845.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVAKILVVSVPNPFEKSNEVKEA"
BASE COUNT         5047 a         2443 c         1560 g         5531 t
ORIGIN      
        1 atctataata ctctatttaa aaattcactt tttttattat atctatttat aatcttttaa
       61 gttactactt gttatacagc tactagtata tataaaatat ttaatattcc attggttttt
      121 cgccatttaa tattttacat attgaacttg tacctaatct ttgtgcacct gcttctatga
      181 atttttctgc atcagatatt gattttatcc ccccagcagc ctttatctta acaccttcac
      241 caatgtgctt tttcataagt tttatatctt ctagagttgc tccatttgtt cccataccag
      301 ttgatgtctt tataaagtct gcacctgaat ttgttacgat ttcacacatc tttatttttt
      361 catattcatt cagataacac gtctctataa ttacttttaa taccttatct ccaatgacac
      421 tttttatttc ctttatttca ttttctattt tttcatattc ctcatttttt atatcagaaa
      481 tgtttacaac catatcaatt tcaactgctc cattttcaat agcatctttt gcctcaaata
      541 cctttacttt agtagtttga taccctaaag gaaaacctat tactgtgcaa atatttactc
      601 ttccatttaa atactcagta gcacttttta catatgatgg tggtatacaa actgatgcta
      661 cattcattct tacagcttca tcacacaaag ttttaatgtc tttcaatgta gttgttgcct
      721 ttaacatagt atggtctact gtctgtaata tatgtttcat aaaaacctcc taagtgtata
      781 attaagttac ttttttaaat gcaatttcct tttggcaatg tttaatatca tgtcaacctc
      841 ttcaacttta aaaagaatca tcagtaatgt ataaactgag aatccaatta ctactgaaat
      901 cgtcagagat attaattcat taagtgtccc taaacccaat ataccaaaaa taaatttata
      961 aataaaatat gctatgaaac tcataacaca tgaagatact aatgatttaa aaattgctct
     1021 tattatttta tcttgcccaa aatatcctac ttttctcttt aagtttaaaa aaagtaacaa
     1081 tatacatgct attgatgatg agctagttgc caacgcaaga cctccatggg ccataggttt
     1141 tatcaaagct aaatccaata atatattaac tccaactgat acaataccat ttaccatagg
     1201 tgtttttgta tcctgtaaag aataaaaaac ttttcctaat atgtctctta atccaaaagc
     1261 tgtcatccca actgcataaa aaactaaagc agtagctgtc atttgagtag ctctagaatc
     1321 aaatgctcct ctttcaaata taattctaac aacaggctta gcaaatacaa tagatgcaac
     1381 agaaattgga atcatagaaa ttattatcat atttacacta gacttaaccg aaattgtaaa
     1441 ctttttttgg ttattttctg cacttaattt cgataacgta ggatacatta cagatactat
     1501 tgaagctgta aatgttcctg taacaaaccc atttaaccta tctgcataag taagtgctgg
     1561 aatactcccc ttaatcagtg tagatgctaa tgttgtatct accagcgaat ttacttgatt
     1621 tacagctacg cctataaata caggtgataa tagagccagt agctttatta aactttcatc
     1681 tttaaagtcc aaataaaata aatatttata ttttgtttta ttcacaaaaa acagataaaa
     1741 aaatagctga actaccatag ctactacagc cccaacagga agtacatatg gtcctaacac
     1801 agtacttaat actattgaaa taattattac aatattataa ggtatactac caaacccaac
     1861 tacaataaaa ttttctttta tttgtaaaaa agcagacata acactggtaa tccctataaa
     1921 tattatccca attataagta ttctagtgaa ttttacagta agtaaaaatc tttctccctc
     1981 aaatcctatg gcaaatatac ttacaagttg ttttgaaaaa ataactccta atattgctac
     2041 aattatgcat ataccaacta ttatatttaa aacattgttt aaaaacttta atgcctcttt
     2101 ttctcctttt ttactattta tatcttgata cataggaata aaggtagtaa ctatagcagt
     2161 tcctattgct gcaaatataa tatttggtat attcatagct gttaaataac tttctgtata
     2221 caagccagtc ccataaatcg aagataacac tagttctcta cccattccaa gaattttaga
     2281 tattatagtg actatcatta aataaaaagc tgctctagct actctgctca ttttatcact
     2341 ccactcttct cgcgtttctt cataattttt ttagaagaaa agtacttata tcagctatat
     2401 ttctaaatac cattttttat tttttatcaa tcaataattt taaaagtagt ggacacagaa
     2461 aatcactact tattttcaaa gtatattcta tcatatattg ttcattatga aaacttttta
     2521 tcttttgtct tatttcttta ggtattttaa atatataaag actagaaatt ttactccatg
     2581 tgaaacttat aagcaataac aatgtttaca tggagtaaat aaaaactacc caaaatttgg
     2641 ataaacaact tcttctaatg gtttttcaat aggttttgca tctatataat tgagaaatgc
     2701 agtcttatta ctagaatttt tttgttcctt atattcaatt ttacctgtta atagaatcca
     2761 ttctccctct ttccatttag gaggttgatt catattgaca attggaccac tcgaaatcat
     2821 gtcagctgca cagcatacca taattgaacg tgaagctata aactgatttt tttcaagaga
     2881 atcatcataa tgaacaaata ctacatatgt tacttctttt cccttaagaa ctgactgttt
     2941 tgtatatagt aaattgagaa aatcatatat ttctgtatca aatacgtcaa atttttcatc
     3001 atatatccgt tcttctaatg ttctatctag aaattcttct ttttcatata ttttatcttg
     3061 atatttttct tttcccttat acttttcaac tttcgttttt tctttatcta tattcaaacc
     3121 actatacgat attagtaatg ttgttattaa aaatgataaa ataatatatt tagtacttcc
     3181 atactgataa atatgcttag gttttgttag tatcatgatg taagaaagtg ctatgaatag
     3241 taatatacaa attgaaatta ctaaatatgg aatcatcctt gggtgtatat aatacacaat
     3301 ttcttttttc cataataaat atataatctg aattaatact accataactg ttaataattt
     3361 tatcaaacac tctttattta tatttttcat aatcaatctt accttttctg aaccctccct
     3421 tgactaaagt cgcaaggttc ctgcttcata aaattttaca taatcaaact ttaagataac
     3481 tgacgtaaat aataaaattt attctttact ataaaaagat aaatgctaaa ttataatttt
     3541 atttccatat tgaaaaaaac aaaatacata atgtagcaaa caagtagaat tataataaaa
     3601 atggtcataa attttttgct gaatcttgat gacattacaa ttaaattctt aatatccaac
     3661 aaaggaccaa ataccataaa tggtattacg ctcataagtg gtagagaatt agtaaatccc
     3721 ttagcaataa aagcattact tgaagcacat atagaaagaa aaacagatgc aaagaacata
     3781 tacaaaaatg catagtcatt agtgaaataa cctgaaaatg ctggattcat tttaagaatt
     3841 tgtgcaatag tagaaataaa tgcgccaata attataaaca tcattattct taaaaattca
     3901 tttcctatat gaataccaag tgcaaggaat ctaaacttct tacctttttt agtaattttt
     3961 gtaatttcat attcaatatt attaaataaa ggtattttat tttttttata tggagaaaag
     4021 tttttatttt tttcaacaaa ataaaaactt attcctacaa gagcagaaag cataatacta
     4081 actaatattc ttatccatat taccttatta ttttcaggaa aagcataaat tgttgccaat
     4141 ataacaatag gattaatact tgatgatata cagaaaaaag tcatagcatg tgatactttt
     4201 aaacctttct gtataaactt ttctgtaatt ggaaccattg cacaatcaca taatggtaaa
     4261 atacaaccca taaataaaaa aattggataa gataatactt tatgtctact agcaaaatat
     4321 ataaacttct cttccgaaac aagaaattgt atacaagaag aaaggacaat cccaattaaa
     4381 agaaatggta tagcctgaag tattatgcca aagaacattc tattaaaatc attgatatct
     4441 tgtactttaa taatttgtat tttgaccccc aataataata aaaaaaacag tataactata
     4501 acaaacttaa taattctata aataagattt ttaagtttta aacttagagg aaaaattttt
     4561 ttgtaattac cagattcatc aatataaaaa atatccgcag aaggttgtag tgctcttata
     4621 tacgatgtaa ttttttctgt tttttcaatt gaattacttc cactaatata aaattcatca
     4681 ctatttatta tctgctcaac catggaatct atatttctaa aatacacatc aaatgtatct
     4741 gcattgacta aacagtatat cttccctaaa taacatgaat atggaagctt tatatcaaga
     4801 aactcctcta tattccatgt cccattgtat tcaatcaaaa tgtaattata cagattacta
     4861 catttcttaa gatattcttt tgtcaaacaa ttaatatctt taaatcgctc tatctttata
     4921 tagtttttcg aagaaaatgg aattgaatat tcagtaaaac cttcctctaa tacaattaat
     4981 aaaatattat ctttatcatc atattgttta ttccttaaat attcattaat aaacttagtc
     5041 tttccagatt ctaagaatcc agctactata tcaattctag tactcattta aacaaaagct
     5101 ctttctaact tttctttatt tggtttaaag ccaactacac aaatacaacc actacttatg
     5161 taattacaag gtataacctt tatttcgtca ggcacaaagc taaactcgta aaacaaacca
     5221 tcttcacatt taaatatgcc ctttgctcta ataatatttc caaaactacc actattgaac
     5281 tgttctaaaa tctcttttat atattcatac ttatagcttt tttctagttt aataccccaa
     5341 ctactaaata catcatctgc attatgtact acatgattat ggtgacagtt acaatgcata
     5401 tcattctcac tatgtactac agattttgta ctcataatat aattaacaat agtctcatct
     5461 aataaattct gctctaaaga tacaatatat tttttatgat acttgttttg tatggaactt
     5521 ataacttccc ttacttttat ttcatcacat acatcaactc tagataacaa aacagcatca
     5581 caatatttaa tctggtcatc ataaaactct ttaaagtttt ttaaataaac actatatttc
     5641 attacatcaa ctattgtaaa cttgtgattt atactcacta aattttgttt aactaatgga
     5701 atacaatttt gtattacttc actcagtttt ccaactccag atggttctac aattactgtg
     5761 tctggcttaa ataattctat aacctctttt aatgatttcg taaaatccgt atttaaagaa
     5821 cagcaaatac aaccagaata gagttctctt acttgaatat tttcattttt aaacagtagt
     5881 ccatcaactc caacctctcc atattcattt tcaataagta ctactttttt atctttataa
     5941 taagcactta gtaacttttt aataaaagtt gtcttaccag agcctagaaa tcctgatata
     6001 atatcaattt ttatcatttg cacctctccc ttttattttt tatttgttct taccttagtc
     6061 taacgttttt atttagactc tctttttgta cagaagaata atcattaatg ttatgctacc
     6121 taaaataaca atagctcctc ctggactaag tcctatataa tatgaaatag tcaatcctga
     6181 taatacgaac aacattgata agaaaattgc aataagtaat gttgatttat aactttttcc
     6241 tagtattaat ccacatgcca ctgggagtac taataatgaa gaaataatca aagctccaac
     6301 aactcttgca gaaattgaaa tagtaagccc aattaaaatt gtgaataata tatctatttt
     6361 tctagtattt acataatgtt tttgtgcttc tttttcattg aaagcataaa acataaactc
     6421 ataataatac ttaaaaaata taatcaaaat caatatggtc aaggcaatta ctaaagcaaa
     6481 ctctctccca ctaattgata taatactccc aaataaaaaa ctatttatat ttacactaga
     6541 ttttatgtag tttgatagta ttccactaat tcctacacct aatgataaaa taacagcaat
     6601 agctatttct tcattatgtt tcattctttt acctataata gaaactgaaa aagaggctat
     6661 tatacaactc ataattgctc ctattgtagg actaatgcca accacaagac caaagcatac
     6721 acctgcaagt gctgtatgtg acaatgcatc tcccaacatt gaaaattttc ttaataccaa
     6781 aattaaacct acacagggaa ttgcaatgct cacacataga ccaacaaata aggctctttg
     6841 cataaatccg taactaagca tagtttaata cctcgcattt tattgtatga ttctcacata
     6901 ttaatatctt gtctgcaatt ttttttaatt gttcataatc atgtaatata agaagaattg
     6961 tatgtccatt attatgtaaa tccattatca tatccattac agatatttta tttacctcat
     7021 ctagtgcatt taaaggttca tcaaataata ttatatcggg atgattcata attgatttta
     7081 atatcattga tttttgtaat tgaccaccag atagagattt aagctgtttt tttgcataat
     7141 gttccatatt atactttctt agtagcatca ttacattttt cttattttta aacaactttg
     7201 acttttcttt atgttgatac attagtaaaa actccatcaa tgttaatggc gaaccttctg
     7261 ccatcactct atcattttga cctaaaaaac tcgtagttaa tgaatcaaaa gtaaaaatct
     7321 ctccactttg taacttaact tcctttgtaa taattttaaa tagtgttgat ttcccactac
     7381 cattttctcc ataaactcca accaactcat ttttatttat atttacattt acacttttaa
     7441 aaacattgca atctgtatac gaaaatgctc catcttttat ttccactata tttttcatac
     7501 ttattttgat aatgcatata ccaagttttg aagattagtt ttcataactg atatatagtc
     7561 ctccccctct tttatttttt tatcagataa ttcttctaat gtgtttaata cttttgtttc
     7621 tgaacctgtc tcttttgcta ttgtctcagc tacttttgga tttacaagtt cttcataaaa
     7681 tataaccttg attttattct ttttagcaga tttaataatt tctgccatac gtgcagggct
     7741 tggttctgaa tctggagaca atccttcaat tgcaatctgt tttaaattat agtctttgca
     7801 aagataacca aatgcttgat gagccacaac tatagaacgt cctttatatg gaagtagttc
     7861 ctttttgtat tgtgagtcta aagcatcaaa ttcacttgca tacttataat aattcttctc
     7921 ataatatgta gcattatctg ggtctttttt acaaaaagca ttttttattt tctctaactc
     7981 tttctttgca ttacgaatac taagccatgt atgagggtcc atactgtctg aacttttttc
     8041 tcctttcatc aaatcaattc catcacttgc tttgacaatc aaaatatttc tattatccaa
     8101 gctttgtata acatcattga cccaatgttc catattgtct ccattgtaga taaacatgtc
     8161 agcattgctc aatcctttta tatcattcgt tgttggctca aaatcatgag gctcaattcc
     8221 agcaggtgtc atgtttttaa catcaacctt agttccacca atttttttag caaaatcata
     8281 cattggataa aaactagtat atacactcaa ttttttgttt gagcttgtct ttttaacatc
     8341 tttgaaacta cacccagtca atagtaataa actacagcaa aataataata caaatctttt
     8401 cataatcgcc ctcctttttg caaatgcttt gcatttgcat ttttataagg attatctcat
     8461 ttttttctct atttgtcaac taattgtgtt gttaaattat atcttatgat atatgataat
     8521 aatagaatca taaaagaatg gtggttttat atatgaataa ttatttgaaa aaacacaact
     8581 taaagagtac agaaaaaaga gaggctgtaa ttaaagtatt agaaaatagc aatgtaccta
     8641 tgacaataga aagtattcac gaaaaagcaa atactatagt agaaatgaat ttaagtacta
     8701 tttacagaac aataacaact ttatgcgaaa agaatattac agttttagta gctatacatg
     8761 atggaaaatc ttattatcag cttaacaagc atagacatga gcatgtatta atttgtaaag
     8821 aatgtaaaga tattattatc attgacgaat gccccttaca tgagctagaa cataaacttg
     8881 aagatgaaac tggttttgat attatcgaac ataagttaga atttattggc atatgtccta
     8941 aatgtaaaag aacgaactct agaacataag ctcatctctc ttttttattt aacttgtttt
     9001 tcttattaaa tatataatta tagattatat aaagttaata aggaaagata attgcaaggc
     9061 ttaatgaaat tatttttaga aaaagtttct actaagtctt gaaatactta tatatattat
     9121 ttcaataaaa ttttatttct aagataataa ttaaatctct atttattaac ttaaatttaa
     9181 atttatttct tcaaaataaa cacttaaata agctataagg aataacccta tctgtaattt
     9241 tagctactag cgaatgataa aatatatcaa ttctgtagat acttttaatg tgtattgata
     9301 aagacttgtt tctgttaaac ataaaaagtg tgctccttcc tttatatgat gatatttgat
     9361 attttaatta tcaccacttt tggaagaata cacactttat tttaaatacc ttttgtactc
     9421 tattttatat aatttctaac aacttaataa aaatgcttta attgttttaa cttacttgga
     9481 tgtcttaact ttcttattgc tttagcttct atttgtctta ttcgttctct agtaactcca
     9541 aatacccttc caatctgttc taatgtctta gggtcatcat catcaattcc aaatctcatt
     9601 cttaaaactt gctgttcttg ctctccaaga cctgtaagca attcttctat tttttctttt
     9661 aaattatgtt gttcaacctc atgcatcaca acatccttaa aatcagcatc tgatggtata
     9721 aattcaacta aactactatc ctcatcttct tttaatggag tatccaaaga tacaacattt
     9781 ttatctcgtc ttaataattc caatacttta tcaacttcta atccacatgc atctgcaatc
     9841 tcatctatag ttggctctct taataataca ttcaaaagtt cttgtttctt tttctttaca
     9901 aaatttattc tctgatgaag atgtataggt atcctaatag tattttcgca atcgtcgata
     9961 tatcttgtta tactttgttt tatccaccaa gttgcataag tgctaaattt gtatcctttt
    10021 ttataatcgt acttttctac agcttttata agtcctatat ttcctgcttg aattaaatcc
    10081 aacatatcaa tactatctct tttatatctc tttgctatgc tcactaccaa cctataattt
    10141 gaatttataa atttttcttt tgctactgaa gatgagttga ttatttcctt agccagctct
    10201 acctcttctc ctgctgacaa cattttgtat tcctctattt cctttaaata cattttcatc
    10261 gcatttgata catttgatga acccacacaa atataatttt cataattatt ttctttttta
    10321 gtatccataa tcaaacccct tctattcata gaatttgcta aaacaaaaat aaataattta
    10381 aacctacata agctacaatt acataatatc ccattcttca aatgaattgt tttgtatatt
    10441 atgtatacaa atttataaaa actataccta taatattatt ctacttctaa cagcaatatc
    10501 ctccttatat atataattta ttttattata tgttgttata ttcttagtct ttagaatgat
    10561 atatgtctaa aaaaagactg tttactaaac agtctttttt tatatatatg ctcaatattt
    10621 aattttcatg atgatgatta catccacatc cacaattttc atcatggtga tgatgttctt
    10681 ctaaatcttt tacctgttgt tccatttcat gaaactcttt taccattata tcataagttg
    10741 gaagagctgc ctcagtatcg tattcttcac ctctccaatc agcgtacatc atagcatctc
    10801 cattagttaa aaccaatcta cctgacatag ttatattgtc cacttcttct aaaaattcta
    10861 tttgtttttg taaaacttct ccttctaact ccacatcttc atctaaacat tgtactatca
    10921 ttacaggtgc ataataatct tcttcatctt taacatttac aacaatatct aaaattcctt
    10981 ctgcaccttc ttcaaactct gccaactcaa catttgtatc aatcatatct tgaggtacta
    11041 ataagtcttc tattaaatat tttattactc tatcttttac taattctttt gacatttatt
    11101 tttctccttc cgattctata acattatcat aatcatttct atattatagt atactacatt
    11161 aattgttttt tcaatctctt acaaaaatta tttttttgtt atcttcctta tatttccttt
    11221 tttattacaa agttgtaatc gcattgattt aaaaaatagt ttatatttag tataatagaa
    11281 atgtaacaca tatttttatt caatatatta ataaaaaata gattgaaaat gtaatgtatg
    11341 ttaaatctag gaggaatatt atgaagttta aaaaacaaat tagttctatt gttgtgtcta
    11401 ctatgcttgt acttggaagt atgaatcttt cttatgcaga tggtacaaat gtagttacac
    11461 ttggagctaa cttatcagag tctcagaagc agcaaatgct taattacttt ggagtaaaaa
    11521 aagaccaagt cttagtttta gatgtaacaa atgcagaaga aagacaatat ttacaaggtg
    11581 ttgcaacaga gggtcaactt ggaaaagtta ctatatcttg ttcatatgtt gaaccaacta
    11641 aaaaaggaaa tggaattaat gttaaaacag caaacttaac ttgggtaact agctcaatga
    11701 ttgcttcaac acttacaaca gctggtcttg aagatgcaaa tgttattgct gctgctccat
    11761 atcctgtaag tggtactgga gcattgacag gaatcatgaa agcatttgag gatgcttcag
    11821 gaaagaagct tgatgagacg aagaaagaaa ttgcttctga agaattggtg gttacaggtg
    11881 atttaggaga cgatataggg caagaaaaag caacaggtgt aatgaatgat ataaaaacag
    11941 aaattgtaaa gaatggtaca aaagatacca atcaaatagc aaatacaata aataatgttg
    12001 taaataatta caatattact attacaccag aacaaaaaga acaaattaaa ggtgtaatga
    12061 aaaaaatagc tgaccaagat tacgattata atagcatgaa aaatacacta gataacgtat
    12121 cagataatgt aaatgaacaa ttaaagaaat taggtgaaag tgttaagagt tctggtatac
    12181 tagatactat tggtggatgg tttagtggaa taggagactg gttctctggt ttattctcag
    12241 gtggagataa aaaagattta ggaatcttaa ataacactaa tgatgagtct cttggctctg
    12301 atgctgtaat aaattctaca gaaggtgttc aaataaaccc acaaaataat actaattcta
    12361 acagtgacag tgatacaaat aactcaaaga ataatacttc aactaataat gaaaataaag
    12421 ataattctca aacaaatgaa aacgacacaa caaataattc agaaaatcaa tcaaataata
    12481 atgactcagt tggtttcttt gaaaaaataa aaaattggct ttcaggccta ttttaaaaat
    12541 taaacaaata aaaagaattg cctaaaatgg aaattttcta taaaaggcaa ttctctttat
    12601 ttacaataaa tttttattac tcactcattt ttttagattt ttctatacat gcacatatcg
    12661 cttttatcac agaagctcta aaaccttctt cttcaagtac tttaactgcc tctatagtag
    12721 ttccaccagg tgaacatacc atatctttta actcaccagg atgtttccct gtctcaagta
    12781 ccatttttgc agagcccata acagcctgtg atgcaaactt atatgcttgt ggtcttggca
    12841 ttcctgcaat tactgctgca tctgctatag cttctataaa taaaaacaca tatgctggtg
    12901 cagaaccact tgcaccaatt acagcttcta taagatactc tggaactacc tcagtatttc
    12961 caaaagaatt aaatacttct gtaactgctt ctaagtcttc atcgtttata tttttattta
    13021 tagaaagaga agacatggct tcatttacaa gagctggagt atttggcata gttctaacta
    13081 tttttttatc atctcctaca atagactcta tatcctttat agattttcct gctgctattg
    13141 taactataat tttattgtca tctataaaat cttttatctc ttccaaaata tcatcatata
    13201 tatctggttt aacagccaca attactatat cagagcttct agttacttcc tttgaatctt
    13261 ttgtagtgtt tattccaaaa tttgcatata ttctatcaag agtttcttga ctatatgctg
    13321 atgctataac catattaggt tcaactaatt ttgaatttac tattccccct atcatagcgc
    13381 ttgccatatt tcctgcacct atgaatccaa tttttttcac tttagtacct ccttattagc
    13441 taatagtagt tgctaaaatt taagcttctt ttacttcatt agatttttca aatggatttg
    13501 gtacacttac taccaaaatt ttagctacct tattagtata gttaacccaa ttatgattgt
    13561 tcttttcact attatagtgt attgtgtctc ctggatacat ttctatttgc tcatctccca
    13621 aaaacactgt aagagtgccc tctaatacat acacaaactc ctcaccttca tgtacataac
    13681 aacaaatttc ctcactactc ttacttggaa gaatttcaat taatctcggt aacattgttt
    13741 tttcctttaa actagatgat aaatgataat gtataaatgt tgagttttct acatcaaata
    13801 cttctttttc ataacttctt aatacagctc ttttatgctc ttttggcttc ataaaaaagt
    13861 aagttaattc tacatctagt acacttgcta tttttcctaa ggaatctgtt gccacacttg
    13921 ttaatcctct ttcaagttgt gataaaaaac caattgacaa gtttgttttt tcactcatat
    13981 ccttcagtgt catttgcttt tgagttctga gttgctttat ttttgctcct atgtccttat
    14041 tcaaaaccat cacccctaaa taattttaat tttttcataa tataaataca aaaatataaa
    14101 tataggtatt aaacctacct ttatttcatt tttaaaaaat tttataagta ttactataat
    14161 ttattaatct ttttttgtct acatttttac gattatttac gatttatttt tcacacatgt
    14221 atatttaatt tcgccaacta aatatacctt ttttataagc atctactctt tatatataaa
    14281 acttaagtta ttcatacaat tttctttagc tttagttatt aaaatttcaa attatattat
    14341 tatttctaca cattattaca tcctttagta caattataac ataattttac aatttaatga
    14401 tatctattca atgtcttttt ttactctaca acatatttta ttttagagtt tagcactata
    14461 tatatttttt atatacagtc ttgtcaattt ttagattgtc aagaattatt gaagtatttt
    14521 atgaccattt aaattttatt ttctaattcc ttacttaaca aaaattgctt atgataaaaa
    14581 a
//
LOCUS       DAMKOJ010000085        14108 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.092, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000085 DAMKOJ010000000
VERSION     DAMKOJ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14108
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.092"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            435..1328
                     /locus_tag="PC592_002900"
     CDS             435..1328
                     /locus_tag="PC592_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HDF4056846.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELKNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1328..2722
                     /gene="gltA"
                     /locus_tag="PC592_002901"
     CDS             1328..2722
                     /gene="gltA"
                     /locus_tag="PC592_002901"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HDF4056847.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3087..5306
                     /locus_tag="PC592_002902"
     CDS             3087..5306
                     /locus_tag="PC592_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4056848.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIETSKRELENYLEINISLLKALSKDDRFSDSETSLIEKGKLLRPYQKEYNLFMIGI
                     TDTKGNTSSTYREKVGSIKDRPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIIKN
                     NEMIGTIFASFYFQDVNNLISRSNLDDSIKFLMIDKNYTIISHPNKKYVNDKSKILDL
                     EGNIIGTTKSEILKNINEKCQGKFLYWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFQ
                     SLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACSTEDELLNRLSKINKEICNLSTTNSSKYKIVMSSGIYKINKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEETRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LNDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLREIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5459..6205
                     /locus_tag="PC592_002903"
     CDS             5459..6205
                     /locus_tag="PC592_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056849.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIDKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVILDGYDISKLEGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDINIQTRNISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTKINIEQNVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6205..8085
                     /locus_tag="PC592_002904"
     CDS             6205..8085
                     /locus_tag="PC592_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4056850.1"
                     /translation="MDFKKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     MKSGIQSGFTAFMALMTSELIILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTELYFPVKAILLTVVS
                     FMILFLITGPMSLKLLNKKSILELLLGTKKPKKEIKSSKLFGIAGIVCLILGYAMILF
                     GNKLKINGGMYTTTLLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLMYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGESSKNNFPMVYSYFSEHNNEKEYEE
                     LQKIRDTIKRYDYKELSFPILQYNREVLLNVKDYNKLSKELGLDKISSKLRKYEGIII
                     PSSNSQEHINSLKELRNYSIKNLNIKIKKSTNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKMNFHGFDYKNWQNSAKITENLKVKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEMEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFNLENLGILLLISSIYSLYFYLLKKFYTRKVWF
                     FD"
     gene            8204..9595
                     /locus_tag="PC592_002905"
     CDS             8204..9595
                     /locus_tag="PC592_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4056851.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAVLTIGYYIS
                     GKSNLRFSKSNLKLDTKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLAVATIILCMGMV
                     VIMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9702..10742
                     /locus_tag="PC592_002906"
     CDS             9702..10742
                     /locus_tag="PC592_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF4056852.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDESL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11234..11887
                     /locus_tag="PC592_002907"
     CDS             11234..11887
                     /locus_tag="PC592_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF4056853.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFIEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11963..12172
                     /locus_tag="PC592_002908"
     CDS             11963..12172
                     /locus_tag="PC592_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056854.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNVVMIDDGTGTLKQAIF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12312..12878)
                     /locus_tag="PC592_002909"
     CDS             complement(12312..12878)
                     /locus_tag="PC592_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDF4056855.1"
                     /translation="MMNNELSTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNMPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDIAKK"
     gene            13038..13691
                     /locus_tag="PC592_002910"
     CDS             13038..13691
                     /locus_tag="PC592_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDF4056856.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVSLHETSLL
                     MIISVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13849..14025)
                     /locus_tag="PC592_002911"
     CDS             complement(13849..14025)
                     /locus_tag="PC592_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056857.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5549 a         1412 c         2343 g         4804 t
ORIGIN      
        1 atataatatg aaagctggta ttgcaataga ttaaagtctt atacacgttt agtttttaaa
       61 gaaattagtg ttattatgaa aacctaagtt aacttattaa ataaataatt gaataaaaaa
      121 aatttattat gtatttataa aatttttgtt acaaatttgg cataatatag tatactttaa
      181 gtgtgtatta ggttaaatct ataacaaatt agacgtatga tatagactga gtgtttattg
      241 gcatttacaa gaaatttgtt aatatcaact atttgtagtt tgggcagtta taattactat
      301 aggggggatg tccaatacaa aacaatcaac caagaactaa tattatatta taaaaagtta
      361 tagttttgtg tgtttatttt tttaattaaa tttaaagtgg gaaaaatata tttgttagaa
      421 tggagaatag cgagatgagt aataaaatag ttagtaagag acaattaaca gatagtattt
      481 atttaatgga aatagaggca cctagagttg caaaatcttc tcaacctggt caatttataa
      541 taattaaaaa tgacgaaaaa ggagagagga ttcctcttac aatagctgac tatgatagag
      601 aaaaaggaac agtaactatt gtattccaaa cagttggtgc ttcaactaaa aagttagcaa
      661 tgtttgaaga aaacgatttt gtaatggact ttgtaggacc actaggacaa gcaagtgaat
      721 ttatacatga agatatagaa gaattaaaaa ataaaaagat attatttgta gctggtggag
      781 ttggttctgc tccagtttat ccacaagtta aatggtttaa agagcatggt ttagatgtag
      841 atgtaataat tggtgcaaga actaaagaat taattatatt agaagatgat atgaaaaaag
      901 tagctaaaaa tgtatatgta tcaacagatg atggtacata tggatttaat ggaagagtta
      961 cagacctatt aaaagattta gttgataatc aaggtaaaaa atacgaccaa gcaatagtaa
     1021 ttggaccaat gataatgatg aaatttatgt gccaattgac taaagaacta aatataccta
     1081 ctatagtaag tttaaataca ataatgatag atggaacagg tatgtgtggt ggttgtagag
     1141 ttagcgttgg aaatgaaact aagtttgcat gtgtagatgg tcctgaattt gatggtcatt
     1201 tagttgattt tgatcaagca atgagaagac aatctatgta caagactcaa gagggaagag
     1261 ctatgctaaa acttgaagaa ggcgatagtc atcatcatag taattgtgga tgtggaggta
     1321 acaaataatg gatgctaaaa aagtaaaagt accagttaga gagcaagaac ctgctgttag
     1381 agcaacaaat tttgatgaag tatgtttagg gtataataaa gaagaagcta tggcagaagc
     1441 taatagatgt ttagcttgta agaaacctaa atgtgtaggt ggatgtccag taggaatcga
     1501 cataccaggg tttataacaa aaattaaaga agacgatata gaaggtgctg ctaaagtaat
     1561 agctaagagt agctcattac cagccgtttg tggtagagtg tgtccacaag aaagccaatg
     1621 tgaaggtgta tgtatacttg gaataaaatc agatgctgta tcaataggta agttagaaag
     1681 atttgtagca gattggtcaa aagaaaatga cataaattta tctgatacag agcctaagaa
     1741 aaatcaaaag gtagcagtaa taggaagtgg tccagcaggt ctagcttgtg ctggtgactt
     1801 agctaaaaaa ggctatgatg taacaatctt tgaagcaatg catgagccag gtggagtttt
     1861 aacttatgga atacctgaat ttagacttcc aaaacaagct gttgttcaac ctgaaataga
     1921 taatataaga aaattaggtg taaaaataga gactaatgta attgttggta aaacaattac
     1981 agtagatgaa cttatagaag atgaaggatt tgaagctata ttcataggtt caggagctgg
     2041 tcttccaatg tttatgaata taccaggaga aaatgcaaat ggagtatttt ctgcaaatga
     2101 gtttttaact agagtaaact taatgaaggc ttatagagat gactatgata cacctattag
     2161 ttctggtaaa aaagttgctg tagtaggtgg tggaaatgtt gctatggacg ctgctagaac
     2221 tgcactaaga ttgggttcag aatcatatat agtttataga agaagtgaaa aagagctccc
     2281 agcaagagct gaagaagttc atcatgcaaa agaagaaggt attatattta atacactaac
     2341 aaatcctaag gaaattttag tggatgaaaa tggatatgtt aaaggtatgg tttgtataag
     2401 aatggaatta ggagagccag atgattctgg aagaagaaga cctatagaaa tagaaggttc
     2461 tgaatttgta cttgatgtag atacagttat aatgtcactt ggaacaagtc caaatccact
     2521 aatatcttct acaacaaaga gtcttgatat aaataagaag agatgtttaa taacagatga
     2581 aaacggtcaa acttctaaag aaggtgtgtt tgcaggtgga gatgctgtta ctggagcagc
     2641 aacagtaata tctgcaatgg gtgctggtaa aacagcagca gcatcaatag atgaatattt
     2701 aaaagcaaaa gttaatgctt aatttgtaaa ttaaagagag ggtgtctcaa aatgaacttt
     2761 gtagtccatg aggcactctt tttgtacaaa atcaaatata ttttaatcat ttcaacgatg
     2821 aaaatttcat tcctgtataa agtctaacct ttaggtctta gcacaatctc tattttgatg
     2881 tatccacttt ttcagattgt ttaataattt ataagttatt attgtaatat ttaatactaa
     2941 gtaacataac tctgtataac tatgataaaa tagttataca ataaaggtct ataaggagtg
     3001 aataatgtgt ggctaataaa atcagatttg tcaaatctag cattagataa tagaaaaata
     3061 aattgtataa ttaatggtat tttaatatga aaaaaagaga aaaagtattt gatggattag
     3121 tttttaagca tatattaatt ttactaatat tattagtttt gattgattta acaagcacca
     3181 tcatatatgc aagtaattct atggaaatta cttctagaaa tatgatagag acatcaaaaa
     3241 gagaacttga aaactattta gaaataaaca tatctttatt aaaagctctt agtaaagatg
     3301 atagattttc tgatagtgaa acatctctaa ttgaaaaggg aaaattatta agaccatatc
     3361 aaaaagaata taatcttttt atgattggta taacagatac aaaaggaaat acttcaagta
     3421 catataggga aaaggttggc tcaattaagg ataggcctag ttttgaaaaa gcaattaaaa
     3481 caaagcaagt agtagtctca gatattgaag ttagcaatgt gacaggtgat aaggtattta
     3541 ttatatatgt accaattata aaaaataatg agatgattgg aactattttt gcttcttttt
     3601 attttcaaga cgtaaataat ttaataagta gaagcaatct tgatgattct attaaatttc
     3661 taatgataga taaaaattat actattattt ctcatccaaa caaaaaatat gtaaatgata
     3721 aaagtaagat tcttgattta gaaggaaata ttatagggac tactaaaagt gaaattttaa
     3781 aaaatataaa tgagaagtgt caaggtaaat ttttatattg ggataattgg agattatata
     3841 atgtaaaata tacgaacata aagtggacca attggacttt agtatcaaaa tgtaatatat
     3901 ttaagaactt tcaaagtcta atagttaatt ttatgataaa gttgtatttt tatatagtaa
     3961 tatttatgat attgtggaaa ttaagtaacg ctaagttaat agaacaactt aaaaaattgg
     4021 cttattatga ttctttaagt ggaataaaaa ataaagaaaa gtttagaaaa gattctatgt
     4081 atattttaaa gaattattat caggataatt tttacttagt acaattagat gtcaataaat
     4141 ttaaatacat aaatgaaatg tttggctatg ctgaaggaaa taagatatta atacatatct
     4201 cacaggtttt aaataataat acaaataaat atgaaatttg tgctaggatg gataatgacc
     4261 attttatatt gttgattgct tgtagcactg aagatgaact tttaaataga ttatctaaaa
     4321 taaataaaga aatttgtaat ttaagtacta ctaactcatc taagtataaa attgttatgt
     4381 caagtggaat atataagatt aataaaaagg atgatattaa aaagattgac ctgttaattg
     4441 atagagcaaa tattgcagcc aaaagcaaaa aggaaaaata tgaacactca tattcatttt
     4501 ttaatgaaga aacaagaaat cgattgtata aggaaaaacg attggaagat aatatgaata
     4561 aagctttaga aaaaggtgaa tttatagtgt attaccaacc taagtatagt ttaaatgatg
     4621 taaatgaaat tgaaggagca gaagctttga taagatggaa tagtccagaa tttgggttta
     4681 tttcacctat agattttgta cctttatttg aaaagaatgg ttttattgta aatattgata
     4741 tgttcgtgtt tgaagaagta tgcaaaacat taaataagtg gataaataaa ggttatactc
     4801 ctgtaccaat ttctgtaaat atgtctagag ttcatttata tagggacaat tttatagaaa
     4861 atataactga tttgataagt aaatacaata tatctcctga gtttattgaa cttgaactaa
     4921 cagaaagcgt tgtgtttgat aatttaaata tattgattga tataatgaaa aagattaaag
     4981 aaataggatt tcttatatca atggatgatt ttggttcagg atattcatct ttaaatctgt
     5041 taaaagacct ttcttttgac attttaaaat tggatagagg atttttaatc gaaacaacag
     5101 atacaaaacg tggaaaaatt attatttcta agattgtgga gatggcaaaa gcgattgata
     5161 ttaaagtaat ctgtgaaggt gtagaaactt atgaacaagt agagttctta agagagatag
     5221 gttgtgataa ggttcaagga tacttatttg ctaagcctat ggtattagat gaatttgaaa
     5281 aacacttaaa ctttaaattt gattaatcat aatcattaat aattattata ctattagata
     5341 ctctaacaac ttacttacaa atatgtaagt taattgttag ggtattttta tggttaaaat
     5401 agtatattca cgatattatg gtattgtagt aaaaataaaa agttatggag aatataaaat
     5461 gaacatattg agtattagaa atatatcaaa aacatattgt ggaaatattc catttaaagc
     5521 attagataag gttagtttaa atatagataa aggagaattt gtgtctgtta tgggaccatc
     5581 tggaagtggc aaatctactc ttttaaatat aatatctaca gttgatagac agagtgaagg
     5641 tgaggttata ttagatggat atgatataag taaattagaa ggagaaaaac ttgctgaatt
     5701 tagaaggaaa caacttggtt ttgtatttca ggatttcaat ttgattgata ctttaactgt
     5761 tggcgaaaat attatgttgc cacttacact agaaggggca agtattaaag atattaatat
     5821 acaaactaga aatatctcta aatttttagg aatagataaa attttagata gaaaaaccta
     5881 tgaaatttca ggagggcaag ctcaaaggtg tgctattgct agagccatta taaataaacc
     5941 tgccatactt cttgcagatg aaccaactgg aaatcttgac tcaaaatcta ctgatgatgt
     6001 tctgaaatta tttactaaga taaacataga acaaaatgta acaacactta tggtaactca
     6061 tgaagcatat agtgcaagtt attcagatag agtgattttt ataaaagatg gttgtatata
     6121 tacagaaata aaaaaatctg aaagcagtaa ttctttctat tctgatatac tagctgtatt
     6181 gtctcaaata ggaggtgtaa gatagtggat tttaaaaaat ttgcttataa taatatagtt
     6241 agaaatttta gagcatattt agcatatttt ttaagttcgg ttttttctat aatgatattt
     6301 tttgtctttg cagtatctat gtttcatcca attataatga aatctggaat ccaaagtggc
     6361 tttactgcat ttatggctct tatgacttca gaattaataa tcttaggttt tagtctactt
     6421 tttatattgt attctttagg aaacttttta aaatatagat tgaaagattt tggagtattg
     6481 atgataattg gaatgagtaa cagacaactg aaaaaattga tattaattga aaatttgata
     6541 atagggtttt tagcagtgat gttaggaata ttacttggtt tatcaatttc caaattgttt
     6601 ttattgtatt taagcaaact gttttatatg aatttaactg aactttattt tccggtaaaa
     6661 gcaatactat tgactgttgt atcatttatg attttgtttt taataacagg accaatgagc
     6721 ttaaaattat taaataaaaa gagtatttta gagcttttac taggtacaaa aaagcctaaa
     6781 aaagagataa aatcttcaaa gttatttgga atagctggta tagtatgtct tatattagga
     6841 tatgctatga tactatttgg caataagtta aaaataaatg gaggtatgta tacaacaaca
     6901 ctgttaatta ctttggggat atttttattt ttttctcaat ttacgatttt gatattaaag
     6961 tatttaaaaa ataaggaaaa attttataag aacaaagtaa atatgttact tataagtaat
     7021 ttgatgtata aattaaagga taatacacga ttgttatttt taataacaat tcttttatca
     7081 gccactttag tagcatttac aacaacttca acacttgtaa gttctcaagg agaatcttct
     7141 aaaaataatt ttccaatggt ttactcatat ttttcagagc ataataatga aaaagaatat
     7201 gaagaactac aaaaaatcag agatacaatc aaaagatatg attataagga gttaagtttt
     7261 cctatacttc aatataatag ggaagtctta ctaaatgtaa aggattataa caaactatca
     7321 aaggaattgg gattagataa aattagttca aagttaagaa agtatgaagg tattataatt
     7381 cctagtagca attcacaaga acatataaac tctttaaaag aattaagaaa ttatagtata
     7441 aaaaatttaa atataaaaat aaaaaaatca acaaataaaa taatttttcc tacaggattg
     7501 ttcagtaaag tagtagttat aagtgacgat ttatacaatg aagtaaaggg tgaattttca
     7561 aaaatgaatt ttcatggatt cgattataaa aactggcaaa acagtgcaaa gataactgaa
     7621 aatttaaaag taaaacattt taatttggat agagaatata acaggtcata ttttttaaca
     7681 ttaccagata tgtatttagt agagttacaa caaagtaaaa ttcttcaatt tatgggtgtt
     7741 tttataggag tcatattatt tatagcagtt tttagttttt tatatttcag attatataca
     7801 gatgagatgg aagataatgt aaaatataaa aaactatcaa aaataggtct atcttttaaa
     7861 aatatgaata agattgttag tatagagata ggaacattat tttttatacc gtattttata
     7921 gcaattataa atagcataat ttctttattg tttttaaatc aagtattaaa taatagtttt
     7981 aacttagaaa atctgggtat attactacta atatcatcta tatattcact ttatttttat
     8041 ctattaaaaa aattttatac tagaaaagtt tggttttttg attaaagtgg tatataatag
     8101 atatataaat taatatttaa aaagtagtta atattagggg agggcatttg cacctccctt
     8161 gtaatatgtg gaaaattgaa tattagaaga aggaggagac ttgatggaaa atcaacaatt
     8221 attaggaaca gaacgaatta gtaaattact actaaaatat tctataccag ctataatagg
     8281 tatgttggta aatagtttat ataatgtagt agatagaatt tttattggaa atataccagg
     8341 agttggacca cttgcaataa caggtcttgg tgtgacaatg ccaataatga caataatact
     8401 tgcatttgga atgttgatag gtataggtac tactactacc atatcaataa aacttgggca
     8461 aggtaaagta gaagaggcaa gaaaacttat aggaaatgca atgacgttat ctgtaataac
     8521 aggaattatc ataatgatac ttggaatatt atttgcaaat aaaatactta cattgtttgg
     8581 agcaagtgaa aataccttaa tatatgcaaa atcatatata aatattatat tattaggtac
     8641 agtagtaaat cttctttcct tttctttaaa ccactcaata agagctgatg gtagtcctaa
     8701 aatttcagca ggaataatga tagtaggatg tttaactaat atagttttag actggatatt
     8761 aatatttgga ttcaatttgg gaatacaagg cgctgcaatt gctacagtaa cttctcaagc
     8821 tcttacagct gttttaacta tagggtatta tataagtgga aaatcaaact tacgattcag
     8881 taaatctaat ctaaaattag atacaaagct aataaaagca gtgtttgcaa taggaatgtc
     8941 gccatttgcg atgcaacttg cagcaagttt agttcaagta atatcaaata ttgcactaaa
     9001 aactcatggt ggagatttag ctataggggc tatggctact atttcttcta ttgcaatggt
     9061 atttttgatg cctatctttg gaataaatca aggagcgcaa cctattatag gtttcaatta
     9121 tggagctgaa aaatatgata gggttaaaaa agcatattta ggttcattag cagtagctac
     9181 tataatttta tgtatgggta tggtagtaat tatgcttttc ccagaagcta ttataggtat
     9241 atttaataaa gaccctgaac ttatgaatat atctgttaat ggattaagaa tatacttact
     9301 tatgttgcca attgtaggct tatcagttac aggaacaaat tttatacaat ctataggaaa
     9361 agcaaaaatg gctatgttat tgagcctttt aagacaagta attttattga taccagcagt
     9421 attaattctt cctacattct taggtttaca gggtgtatgg acagctcaac cagtgtctga
     9481 ttttatagct acagtaatta caggtatagt tgtatttaga gaattaaaaa gatatactcc
     9541 taaaactgaa aaattaaatg aaaatgaaag attaaatgag ataactactg agtaaaaata
     9601 taaattcaga taattgagca agaaattgca aaaaatacaa ttatatgata aaataaaacc
     9661 gctgtcaagg ataagagaaa ttctaattat ggagtgattt tatggaattt acaaagaaaa
     9721 gcaaattaaa aaatatgtat gtaaacatga atgtagctag aatgttgtct aagataaatg
     9781 agtataaggg tagacaactg ctttacaaaa aacaaccaaa agaaatttta gaaaacttag
     9841 aaaaaaaatc tttagtagat tgttctgaat ctacatacat tggaaatcaa agagatagta
     9901 gtaattttaa tctagaaaaa ttgataagta atgaagttac acctagaagt agagaggaat
     9961 tgagtattgt tgaatacaga gatgtagtaa aaactattaa cagtgcttat gagagtattc
    10021 caatcagttc acaaacaatt cttgagcttc atggatactt atataaattt tcatctacta
    10081 gaggaggaag ttataaatca gataatgatt ttattgaaca caatttaaaa cctagcgaat
    10141 ttataagtat tgattcaagt gtaaataaag ttgaaaaagc tgtagaagaa atatgtgaag
    10201 cttataatac attgatagag gaagatgaaa ttgatatatt aatattaatt tctgcatttg
    10261 tgctagattt catattgata catccattta aagaaggtaa tataaaaatg gcgagagtac
    10321 ttatcctatt gttactaaat aaaaatggat atgaagttgg aagatatata agtttaggaa
    10381 agatatttga tgatagttca tatgaatatt atagtaattt aaattatttg aaagcgtcta
    10441 taggtagtga aaaagcagat atgaatgcat ggattgagta ttttttagag actatattga
    10501 ctgcatatga gaagctagat gagagtttaa atatatctga taagaaaaga cagacaaaaa
    10561 ctagtagaat agagaaaata ataaattcta cccttggata ttttacaaaa gaagatataa
    10621 gagatttatg tcctgatatt ccagaaccta ctataaatag agtttttaac aatctaagaa
    10681 aacaagataa gatagaagtt gttgcaaggg gaagaagtgc aaaatggaag aaaaaatatt
    10741 aaaaaatatt taaataacta aaatggtata gtgttttgca ctataccatt tttagtatca
    10801 ctagcatggg caataattta atagcttaag caatatcaat tttatttatt gattattttt
    10861 gaactgaaaa aagggattat atggatacct caatggtaat taattttgga ggagaagata
    10921 taacattaca gaatatctta ggtgtatatg tagaaaaaat aaaatataat aaacgtgtga
    10981 ggtttagtaa ttaaaaaatt atgtagcttc gcactttttt ataaaataaa gatacttagc
    11041 agaataatat tttagttgat atatttataa agaggtgctt gtttgggtaa aagtataaat
    11101 aataaaaagt agaagtcatg tatataaaaa tataagctat attctataat aataattatt
    11161 ttataattca acaaaagaat agaatgggta tatttgtgaa ataataatat aaaataatct
    11221 taggagtgag cttatgaaga aaaaattatt atatataaat gtaaattcaa agcctgaaga
    11281 tttatcttca agtaaaactg tagcaagaaa atttataaat aaatttatag aaaaaaacaa
    11341 agattttgag gttgaagaga tagaccttta taaagaacat ataccaagac ttgagtatca
    11401 gtactttgaa aagagaaata gcattgttag cgaagaaaat gctaaaaatc tagacgacaa
    11461 agatagaaaa gaacttacaa agattagaaa tctttgtgac caatttgtga gtgcaagtgt
    11521 atatgtaata gcagcaccta tgtggagttt gtcttttcca gcaccactta aagaatatat
    11581 agattgtata attcaagatg gaaaaactat atcttttgaa ggaaatgata aaccacaagg
    11641 aattttaaat gatattgata gaagtatggt atatatacaa tcctctggtg gacacatacc
    11701 atgggtattg aagccagtta tgaataaagg gttaaattat gtggaaagta ttatgaaatt
    11761 tataggaatt aaaaagtttg atgaattgtt agtagatgga actggaacta gtgaagaaga
    11821 aagacaagct gcaatagaaa aagcatctga aaaaatagat ggtataatag atggtatgaa
    11881 gttttagata taatatttta ttaaaaatat aaaggaaaaa cctcttttaa tgtagaaact
    11941 tatattgaag gaggcgagaa tcatgcgaga agaaaaaagt aatgaaaagt atgattgtta
    12001 ttggtgtaat caagagaata atttctgtgt agaaataaaa gataatgtag ttatgataga
    12061 tgatggcact ggtacattaa aacaagccat tttcataggg tataaacaaa tccaaattaa
    12121 tttaaattgt tcacattgtc aaaacttaaa tagaataaaa ttaaatttgt agaattttaa
    12181 aatggaactt attgaaggaa ttaaaaatag aaagtgttaa tatttagact gaaaattata
    12241 ttttatacaa taagagttta tttaaataac attgtatctt aatatttatt ttcagtctta
    12301 ctttattaaa attatttttt agctatatct ggaaaatatc tatctactaa tttttctgaa
    12361 atgtttttta attggtcagc cattgaagtt aaacttaata aggctatcaa taaatcatct
    12421 ttattttctg gatttatact gatattttca aaattagact ctataaagtc tggcatattc
    12481 tttctttgat tttcttttat caacatgaat ttttcgtaac atgaaactaa atctttctca
    12541 ctgaaattat ccttttcata cacaccatgt aagattcttt taatttcttg tattgtaagt
    12601 gtatttttca tagaataaat aattatcatc tgtaaaattt gttctttagt atactttttt
    12661 cccttaactg gtttgattaa tccctctttg ctgtaattat ttatcatggt tttagtaaga
    12721 attttatcac tttcaaatct tttattagca gaaagcttat tgtcaattag agaaataatt
    12781 tgatccatat acaagtcaat agagggaata tcgtttgaag ttatatctgc attatttagt
    12841 gtttctagta ttatagtact aagttcatta ttcatcatat gttacctcca taatatatat
    12901 aatacactaa attagaaaat aaaacaatat taagacttgt aaaaaaaaca taaagtggta
    12961 taattaaata tataatatag taatgaaaac tatattaatg agtgtgattt ttaaatacat
    13021 aattgtagga ggatgaaatg tatcaatttt ttttaaaggg tagagaccca ataagcagtt
    13081 taactcattt tataggtgct tgtttatctc ttttagcaac tataatttta gtttttcaat
    13141 ctgtttcatt acatgaaact tctctcttga tgataatatc tgtatcagta tttggacttt
    13201 cactaattgc tttatacagt gcaagttcgt attatcattt tttaaagggt acaccagaac
    13261 aagaattgtt ttttagaaaa gtagaccatg caatgattta tgtattgatt gctggttctt
    13321 atacaccaat atgtctaaat tttatggaaa aaaaagaagg cataatattt gttacagcaa
    13381 tatggatagt tgcattcatt ggcataataa taaaaatatt ttggatggat gcacctaggt
    13441 ggttatctac gagtatatat ttacttatgg gttgggcaat tgtttttgat ataaatgcgt
    13501 tcaattcaat tcctaaggat tgccttagac tattaattat ggaaggtgta tcttattcta
    13561 taggtgcaat tatttatata attaaaaagc ctaatataag tcctgaattt ggatttcatg
    13621 aaatatttca tatttttatt atgataggtt ctttatttca ctttttagca gttttattgt
    13681 atgttttata gttttaaaag attcgattaa ttgatactaa aattctacaa tgaataaaat
    13741 ggaactgcct tatatagatt atatcttcga caataagaca gttccttatt ataaatatta
    13801 aattctactt ataataaaat tttgataaaa atagtccatt caaaatgcct attccataat
    13861 tcctttaatg tacttttcat ttacgacata tagtttgaat ttatgtacta taattatatc
    13921 ctctaaattc tctgaaacac taacaattct gacacatttg tttctaattt ctacaggcaa
    13981 atctaaatca tttgttaaat tcacatagtc atcatattta tacataaaat catcccttta
    14041 cattaagata tacttattat actatatttt aataagtttt tttaaattat tacaattttt
    14101 cccgaaat
//
LOCUS       DAMKOJ010000086        13569 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.093, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000086 DAMKOJ010000000
VERSION     DAMKOJ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13569
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.093"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            240..1178
                     /locus_tag="PC592_002912"
     CDS             240..1178
                     /locus_tag="PC592_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4056858.1"
                     /translation="MFRKVLYSLTLLSISIIFLVGCSNSQNKQNANENKEIQSQEDTK
                     KIDSSKDTSNVIVSDGIDKPSKNATNNDNNKLDVSSLDNTALDWFYIPNNKHKTPEVN
                     TDIGFKFSDYDAIYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTY
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKN
                     MVKFFRPPMGKYSEKSLAMTKNLRYKTVFWSFAYRDWDTKKQPPHEEATQKIMANLHD
                     GSILLLHAVSKTSTEILNDFITNARKLGYEFELLEY"
     gene            complement(1535..2908)
                     /locus_tag="PC592_002913"
     CDS             complement(1535..2908)
                     /locus_tag="PC592_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056859.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISVAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYMFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFIPVITGLIVTT
                     IVAMFII"
     gene            complement(3074..4396)
                     /locus_tag="PC592_002914"
     CDS             complement(3074..4396)
                     /locus_tag="PC592_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4056860.1"
                     /translation="MISKIKPSKLGVILLMYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNRLMDDFQTYVNNNGIRADDGDDIAKWNSDNWFVSIKIYKGNRVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIIVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSN
                     TLEKQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            complement(4389..5093)
                     /locus_tag="PC592_002915"
     CDS             complement(4389..5093)
                     /locus_tag="PC592_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4056861.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LADSTIDLIILDVVMPVKTGFVACSEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEKEPNILKTKELCVNLDTQDVTLNGQPVF
                     LTTIEYSILVLMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            complement(5276..6340)
                     /locus_tag="PC592_002916"
     CDS             complement(5276..6340)
                     /locus_tag="PC592_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF4056862.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFIMMFIYVACEGINIYLGMKALRQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGVMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVVGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVITSQI
                     EEYVKGAQYIKQNPKLVVQILVITIIQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     IVHVKSSEKVKSVKKVAYVR"
     gene            complement(6343..7041)
                     /locus_tag="PC592_002917"
     CDS             complement(6343..7041)
                     /locus_tag="PC592_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4056863.1"
                     /translation="MYVVGLIIIVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIIGLHSLEH
                     KNAWLYSYSYVKKDFIESTNIMKNLGVDVSYYRPPWGHTNIFSNLFVKKYNLKMTLWD
                     VMAEDWNKNSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKVAIPK
                     LKASGLKFVTPERM"
     gene            complement(7032..8129)
                     /locus_tag="PC592_002918"
     CDS             complement(7032..8129)
                     /locus_tag="PC592_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF4056864.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEITIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDELLNEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHINHSTKKNILIMGGGLGLLPKSEQFYRELNDL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKGADLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDVTLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGECRECM"
     gene            complement(8454..9698)
                     /locus_tag="PC592_002919"
     CDS             complement(8454..9698)
                     /locus_tag="PC592_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF4056865.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            10026..10814
                     /locus_tag="PC592_002920"
     CDS             10026..10814
                     /locus_tag="PC592_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF4056866.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            10814..11287
                     /locus_tag="PC592_002921"
     CDS             10814..11287
                     /locus_tag="PC592_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF4056867.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGITGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(11379..11819)
                     /locus_tag="PC592_002922"
     CDS             complement(11379..11819)
                     /locus_tag="PC592_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HDF4056868.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGLKTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(11834..12127)
                     /locus_tag="PC592_002923"
     CDS             complement(11834..12127)
                     /locus_tag="PC592_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDF4056869.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            complement(12170..12571)
                     /locus_tag="PC592_002924"
     CDS             complement(12170..12571)
                     /locus_tag="PC592_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056870.1"
                     /translation="MKKCLYCNRDIKSPNNNLSIKYDDNTNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILVFIVIITVLYFKQVGK"
     gene            12804..13448
                     /locus_tag="PC592_002925"
                     /pseudo
     CDS             12804..13448
                     /locus_tag="PC592_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
BASE COUNT         4677 a         2229 c         1606 g         5057 t
ORIGIN      
        1 actcattcaa tgtctttgtg cttgttattt tgttacttct tgttgagcac atttattata
       61 ataacacctt ctaacaatat ggtcaactac ttttttcatt ttttttaaac tttattgatt
      121 attcacccat tgtcatacta ttgtgacttt atttttaaga atgtaactat tattaataat
      181 agtttacaat tataataata ctatatgtag ttgttattaa ttcagaaagg agcttcaaga
      241 tgtttagaaa ggtattatat tctttaacac tactttctat atctattatt ttccttgttg
      301 gatgttcaaa ttcacaaaat aaacaaaatg caaatgaaaa taaggaaata cagtcacaag
      361 aagatacgaa aaaaatagat agtagtaagg atacttccaa tgtaatagtt tcagatggaa
      421 tagataaacc atcaaaaaat gctactaata atgataataa caaattagat gtatcctctt
      481 tagataacac tgctcttgat tggttttata taccaaacaa taagcataag acaccagaag
      541 taaatacaga tattggattt aaattttctg actatgatgc tatatacaat gggcctacaa
      601 aagatggtca gaaaacacta tatcttacat ttgatgaagg ctatgaaaat ggatacacca
      661 caaagatact cgacaccttg aaacaaaatc aggttaaagc agtttttttc gttacatatc
      721 catatataaa ggaaaacaaa gatttagtaa aaagaatggt ttctgagggg catatagttg
      781 gaaatcacag taaaactcat ccatctatgc caacaaaaac aagcaattta aaaaacttta
      841 atgacgaatt atatgatgtt gaaaagttat ataaagatgt aactggaaaa aatatggtta
      901 aattttttag acctcctatg ggaaaatatt cagaaaaaag tttagcaatg actaaaaatt
      961 taagatacaa gactgtattt tggagttttg catatagaga ctgggatact aaaaaacaac
     1021 cacctcatga agaggcaaca caaaaaataa tggctaatct acatgatggt tctatcttgt
     1081 tactacatgc agtttctaaa actagtacag aaattttaaa tgattttata acaaatgcaa
     1141 gaaaactcgg atatgaattt gaactacttg agtattaatg tttagaatta catctaaaat
     1201 ctacaaacta gtatagttaa tatagtatat gtgataaaat aataatttaa aattagaatt
     1261 tttgtttggt aatagtatag gtaaaaaact tgtgatgtct tacatatgtt ggtagtacaa
     1321 gcaataaaaa ctcaataaat ttggcaagat actaaaatag ataatagtat tttagatgtt
     1381 atattagtat aacaaaaaat attattctat caaagaatac tattaaaaat atcaataaaa
     1441 atagatgtat ggcttagaat tagtaaaact gttatgataa attatagcta cacatctatt
     1501 tttagtttgt ataattaaag ttttatttaa ttcattaaat aataaacatt gctactatag
     1561 tggttacaat caatccagtt ataactggta taaaatttcg ctttgccaat tctattggac
     1621 taactccaca aattgccgct gctgaaataa gcccccaagg aactaaacag cctccaccta
     1681 cccatatacc actgatttgt cctaatgcag ccaatgcacc aacacttgca tttatagcag
     1741 ttccaaacac agatgcaagt gaaccaacta atgaaattcc agaaaatcca gaaccatcaa
     1801 gtccagttat tgctcccact acagtttcta tacctgatac agcaaattta ttaagtggta
     1861 ttgtctgaga aagagctatt cctatatctg ataataaacc ttgtgaacct ggtgctaata
     1921 cctttccaaa tacacctgtc aaaggtgcaa cttcacccat atagaaaaaa gctgctattg
     1981 gtataattgc gccaaatatt tttatcccaa acacaaaacc atcaattata ttctcacata
     2041 cattttcaag actatctttg ccaaaattta taacatttat aattattatt aaaaatactg
     2101 ctgttccacc taaaagagct gatgcatctc ctccttttag gtcaaacata tacattgcaa
     2161 ttatatcagc aagaaatcct aaagctacta aaatagttgc tattttagat tttccattaa
     2221 actcttctac ttcttcactt tcaaaacctt ttagttcttc tctaaacatt cctttgttaa
     2281 tgtctctttt caatgtataa aatgccacag atatggttac gattcccatc acccaaaaca
     2341 aaatcatacc atcatttata acatatgata ctgcaactcc tgctgcacca gctgttatac
     2401 ttggagctcc ttgaatgaca aagtctgtag ataaggcaag accatgacca aacaaattta
     2461 atgctactgc aacaccaatt gctggtagtc cagctctcat agcaacaggt agaaatacag
     2521 ctccaactaa ggcaactgct ggagttggcc agaaaaacca agaaagaact aacataacaa
     2581 atccagttac aaaaaatgct gtattagaat tttttataac ccttgaaaac ggtcttacca
     2641 tatactgtat agcattattg gcttctaagg ctttagataa tgcaaccata atagctataa
     2701 ttaagataat tggtcccaac tcatttaaag atataataaa agagttaaac actgctgtta
     2761 tagcaccaaa aatatttttt tcaaagaaca gtcccataaa aaaaacacct aatatacatg
     2821 gtactattgt atcctttttc ataatcatag taattaatat aattaccata aatagaatgt
     2881 aaatataatg tgctcctgtc aaaaccatat tattatgtcc ccttttttta agataataat
     2941 attatatggt tttgtaagta aacttgttac ttgcctagag ttacacaata tcgaaccttc
     3001 cataactaaa gtcacagagt tcctgcttca tagaattttg cataatcaat tacacaatat
     3061 ataatttaaa tttttatgat tcttttgctg gaatagatat ttcaatagca aattctttat
     3121 catctgagtt tacatttata cttccattat gatatgcaac tattttctca caattcttta
     3181 taccaattcc aaaactttct acattcttag aaaaattgct tactctattt ttttgtataa
     3241 ttaataattt agaatcctct actttaatta aaaatactat aggtttatct ttcctagcat
     3301 attttattat attagaacat aaattatcaa atatccttct aaattgtgta acatctacat
     3361 aaatatgata ttggttataa agttcatttt ctattgttat atgaaatcct ttctcctcca
     3421 atgtatatga actatctaaa agtaattgaa aaataaattc attagcattt attttttcat
     3481 acccttttga aacttcctct ccagaattaa caaaatgggt aaaaaggtca tctgttaaat
     3541 cttttatttg atatgcttta gaccttacat tttttatata ctgttccaat tgctcaggac
     3601 tattatattt atggtcttta attaaatcta aataacaaat tactgatgtt aatggagttc
     3661 taacatcatg tgatatcgaa gttactatat ctttattttt attcttcatc tctcgttctt
     3721 ttataagttg cttctccaat gtattgctca tctcattaat actagatgca agtgatgata
     3781 attcatcatt accttttacc gggattctat attttaaact gccactctcc actattttta
     3841 tacccatttc tattttcctt aggtacttta tctttctact aaacaatagt aagaatgtta
     3901 taataaatgt aagtgccata aatgtaatag aaattgcttc tataaaattt tgaaacctaa
     3961 atctaaataa agctactaca attatattag ctttaatatc agaaaattgt atttcataat
     4021 ttctagccat tggactgcta taaaactcat tttcctcact cttatcaggt acttcattag
     4081 gatagtataa tgtatcataa aaaaccctat ttcctttata tatcttaata gaaacaaacc
     4141 aattatcact attccatttt gctatatcat ctccatcatc cgctctgata ccattgttat
     4201 tcacataagt ttgaaaatca tccataagtc gatttacttc tcttttaaaa tatactttcc
     4261 cttctgatac atcttttact atagattcaa cagcagagta aaatggtata tttaaaatga
     4321 aagccactgc agctgagatt actacataca tcaatagtat aactcccaac ttagatggct
     4381 taattttgct aatcaatata ataccccttt ccccatgcgg tttttatata ttgcggattt
     4441 ttttggtctt tttctaactt ttttcttaaa tttctaatat gaaccattat tgtattattt
     4501 gctgtataaa aatactgctc atcccaaata gtttcatata aattttcaga tgagaaaact
     4561 ttttttctat ttttcaacat aagaactaat atactatatt ctatagttgt caaaaacaca
     4621 ggttgtccat ttagtgtaac atcttgagta tctaaattga cacataactc ttttgttttt
     4681 aatatatttg gctctttttc cttttcctta ccctggtata tataataacg tctaagtaac
     4741 gacttaaccc ttgaaattaa ttcagaatat gaaaaaggct ttgataaata gtcatctcct
     4801 cctgctgaaa atccaataac tttatcagaa tcttgagttt ttgcagttaa aaataatatt
     4861 ggtgctgtcg ttttttctct aatttcacta catgcaacaa atcctgtttt tacaggcatt
     4921 acaacatcca aaataatcaa atcaatcgta ctatctgcta agtttacagc ttcttctcca
     4981 ttcgttgcca taataacttc ataaccttca ccagttaaaa gtatttctac gatttctcta
     5041 atttcaggat tatcatcagc tactaaaatt ttttttggaa tttctttatt catcaccaag
     5101 ctcctttttt tgctatattt cttaaatatt tcaaactata taaaatatta tactttatta
     5161 gcaaaagctt agcaatgtca cacgttttaa taccttctac tttggtaaac atgtttaaaa
     5221 cttaattaaa atgtatacac aaattgacat attaataaaa ataatctata taatattatc
     5281 ttacataagc aacttttttt actgatttta ctttttcaga agattttaca tgtactatta
     5341 tacatattaa tccacttata gctacaaatg cgtaaaaact tattcctcta ctaagtaaca
     5401 ttgccggaac taataagtga ccagggaaaa atatcttaaa taatgtcata aaactatttt
     5461 cagaagctcc aacagcccct ggcaatggta atgatgaaac agcaatatta agcaaggatt
     5521 gtatcgctaa tatctcaaac acagtatatg ttgatagatg aaaagctttg tatacaaaga
     5581 aaggaactaa aaacatagct gttatttgta taatagttat gactaaaatt tggactacaa
     5641 gctttggatt ctgctttata tattgcgcac ctttaacata ctcttcaatt tgagatgtta
     5701 taacttttct tgaactttca acatctttta ttattcttaa cttacctaat aagtttgtta
     5761 ttgatattat aaaattattt acaagttttt ttgaaaatat aattgcaatt actccaacaa
     5821 caagagcaac atttgttatt acaccatata ttagtaaaat gttcataccg cttacattat
     5881 ttaatataaa ctcacgttcc ataataaaca ttactccact atatgccaat atgactactt
     5941 gatgaataac aacaatgact aatagtataa gtgaagaata tgatatattt atatcatctt
     6001 ttttcatata ataaacttgt gctggttgac cacctgatgc tgaaggcgta atagaactaa
     6061 aataaaatcc aataaaagca tatcccatac attttaaaag agttgttttt tgtcttaaag
     6121 ctttcatacc taaatatata tttatacctt cacaagcaac atatataaac atcattataa
     6181 atccaattag tataaacata gggcttgcac cttttaatga ttttatcaat gattcaactg
     6241 actgccctct aaaaacaaaa tatcctgtta tgcccattag taaaactaaa aaagctacac
     6301 tacctaggca tttatttttc ttttcagttt tacttatcat aactacatcc tttctggtgt
     6361 tacgaacttt aaaccactgg ctttaagttt tggaatagct acctttaagg cttcaatagt
     6421 acgctcaggt gcacctactg caccacctga attttcacct gcatcatgta aacaaattat
     6481 agaattttct tttgttctac tcattaattt gtttataatg atgtctactg tactattttt
     6541 gttccaatct tctgccatta catcccataa ggtcattttt agattatatt ttttaacaaa
     6601 caaatttgaa aatatattag tatgacccca tggtggacga tagtagctta catctacacc
     6661 taaatttttc attatattcg tactttcaat aaaatctttt ttaacataac tataactata
     6721 aagccatgcg tttttgtgtt ccaatgaatg taaaccaatt atatgatttt ctctcaacat
     6781 tctttttata atttcaggct ctttttcagc attctttgct actacaaaaa acatagcttg
     6841 tatatcattt tcttttaata cgtctagtaa tttttctgta tatctcttat ctggaccatc
     6901 atcaaatgta agtgcaattt cattttctcc agccatattt tttaatacct ctttatttaa
     6961 tagtttattg tagtatgtag gtataattga atggactaaa aaaatcaatg caacaatgat
     7021 aattaaacct actacataca ttccctacac tctccttgtt catcaagtga aaataaaata
     7081 ttttctaagg tattattatc aaactgtttt tttaattctt tcatgttact actcatttct
     7141 ttaagagtaa catcatcata aattaaatct tttatctcat ctacatagta ttttttattt
     7201 ttaccaagta ttctcccaat ttcattattt aatataaaac tagcattatc tatctcttgt
     7261 tgtaaaaatg gattaaatgc caatattgga agttctgaat aaattgtttc gaatagtgtt
     7321 attccacctg gtttagaaat aataaggtca gcacctttca tatatttata tacttcattg
     7381 gtgtaaccta ctacctctat attttcatat ctaccatata gtttatagta cattttttta
     7441 ttattaccag ttattacagt agtctttact ccttctaaat catttaactc tctgtagaat
     7501 tgttctgatt taggtagtaa tcctaatcct ccacccatta taagaatatt ttttttagtt
     7561 gagtgattta tatgttctat tcttttaaat tcttttttta ctggaatacc attaacttta
     7621 atcttagatt catctattcc tttaaaaaca agttcttcct tagtggattt actagctact
     7681 aaataacaat ctgtattttt actaatccat tctgagtgac tacttatatc tgttatgcat
     7741 gtaattaaag gaaggtttga gttatacttt tccttatatc ttgatactaa ttgagaacaa
     7801 aatggaaaag ttgaaataac tactgttggt tgtacttcat taagcaattc atctaattta
     7861 tttaaaaaat aatctgaaaa agtaaatttt atatctttct ttccattttc agcacactta
     7921 taaaacaaat tataaagact acttccccga tttacaagaa tagaaaaagt cttgtacatt
     7981 ttatctgaat agttaggcat aatatattca aatatatctt taattgttat ttctgaatta
     8041 tcaaattttg cttttatatc ttcacttaaa gaatttgatg ctgaataatg acccatacca
     8101 aattttcctg taagaattaa taccttcata agattccctc ctaattaaag cttttctttt
     8161 catataatta ctatacttat aagtatagac tttaaatctt tagaaaaacc tagtataatt
     8221 cttaagaaat cttaaagttt taattaaaaa atacaaagag accatctaaa aatagagata
     8281 accgtatttt ttattattta aataacacaa atatgttcga ttccatacaa aaaagagtgt
     8341 ctcatgaact aaaaagttca ttttgagaca ccttttttat atctacatgt attcaaatac
     8401 atacacaatc attgtaatta tttaaatgta ttttatttag ttgttcttta taattaatcc
     8461 ataatattat attcttcata taaaggatat ttttcagtta aaccaacaac caatgttcta
     8521 gccttagatt cttcatcata agttaaacat aggtctatag cttcagctat tattgccata
     8581 tcttcttctt tcatgcctct agtagttaca gctggagtcc caagtcttat tccactcgta
     8641 acaagagcac catttggatc aaatggaatt gtattcttat tagctgttat gtaagcatca
     8701 tccaatcttt tttctgctgc tttaccagtt atatttttat tagttaaatc taatagtatt
     8761 aaatgattat ctgtacctcc agaaatcaat ttaaaatctc ttttaataag ttcttcagct
     8821 aaggcttttg catttttagc aacttgtact tgatattctt taaactcatc acttaaagct
     8881 tctttaaagc aaactgcctt agaagcaatt atatgttcaa gaggtccgcc ttgaatacca
     8941 gggaatattg ctttgtctat atctttagca tatttttctt tgcaaagaat aacaccccca
     9001 cgaggtcctc ttaaagtttt gtgagttgtt gttgtaacaa aatcagccac ttcacatgga
     9061 ttctggtgaa gacccgcagc aacaaggcct gctatatgag ccatatctac cataagcaat
     9121 gctccaactt catcagctat ctctctaaac tttttaaaat ctatttctct aggatatgca
     9181 cttgctcctg caactatcat tttaggtttt acttcatgtg ctatctttct aacttcatca
     9241 aaatctataa gtccactgtc tttatctata ccatattcat aaaatttata atactgacca
     9301 gaaatattaa ctggagcacc atgagttaaa tgtccacctt gagataaatt cattcccata
     9361 acaacatcac ctggttttaa catagcaaaa tatacaccaa tatttgcatt tgctccagag
     9421 tgaggttgaa cattagcatg ctctgctcca aatatttttt tgattctatc tattgcaaga
     9481 gtttcaactt catctatata ttcacaccca ccataatatc ttttgcctga gtaaccttct
     9541 gcatacttat ttgtaagatg acttcccata gtttccatta ctggaactga tactatattt
     9601 tcagatgcta ttaattcaat atttctttgt tgtcttttta actctctttt catactttca
     9661 taaatctcag gatccgcttt tttcaagttc tcaaacatat tactcctcct agttattatt
     9721 taaattttat ttttacagac atttcataat tttcgttttt atcaatatga taatttatta
     9781 ttatagtcct ttagcaatta atagtcaagt gttttgccat ttttccatat ttaacataat
     9841 tactttcttt atttttaagt taaaatataa taaataatat tgtctaattc ttttaattgg
     9901 atataattta aatgtgacta ttttgaaaca aaaaaaagat aatatattta tatagatatt
     9961 aaggaatatt acttaaaaat ttgatataat ttcaatatta cgttttttaa tttggaggtg
    10021 tatttatgaa tcaaaatgag gaacttgaat ataagaaaaa tattctaaaa ctagctctat
    10081 ttgtagggga acttatgata aaaaatggag ctgaaacatc tagggttgaa gacagtgtcc
    10141 ttagaatatg caggtcaaga gggttttatc atgtaaatat ttttacaact cctacagtaa
    10201 taattatttc agatgagaaa tttgatggct tttcgtttat gaaaacgatt caatcaagag
    10261 gtataaactt aaataagatt tctttattaa atagtttttc tcgagaattt gttagtgaca
    10321 aagagtatga tattgataat gctattgcac gtctttatga aatacaagat gtaaaacctt
    10381 atcctttatg gttattttac tcttgtacag gaattgcatc tgcttgtttt gcttgtttgc
    10441 ttggagggaa ttatgtatta aattttatac ttacgtttat aatagcaatc tttgctgcaa
    10501 ttacttatga taaaacgatg aagataagtg caatatctgc gttttcctgt ttagtatctt
    10561 cttttttaat tgcactttca ggagttctgc tagttgaaat aggcatttta gatgacccta
    10621 aaatgcttat agtcggcgcc ataatgccac tactcccagg agttgctttt ataaaagcta
    10681 ttagagattt aatatcaggt aatttaatat caggaatttc tcgtgctttt gacgctgcta
    10741 tgattattat tgcaattgct tctggagttg gttttgttct tgatacatgg tatagaatag
    10801 gaggtccttt ctaatgactg atatgtcaat gattttacat tttttatttt caggcgttgc
    10861 aactgctgga tttgctgttt tctttaatgc tccactctat ctacttcttc cagctggaat
    10921 aactggagga attggttgga ttgtatatgt ttatttattt aattttacta caaatgccgt
    10981 ttttgcaggt tttatagctg ctgctttggt ctcagcatgc agtgagactt tggcaagaaa
    11041 actaaagcaa ccagctattg tgttcgtaat tccagggatt cttcctctaa taccagggat
    11101 tgggctatat aatacaatgt tgtctttgat tcagaagaat tattctttgg ctatgtcaaa
    11161 aggtacagat gcgctatttc taagtgctgc aatagcactt ggtgtattag ttgtaacttc
    11221 ttttgtaagg acattgaatc ttttgaaaat cagaaaaaac tttattcctt acagaaaatc
    11281 aaaataaaaa tataaaaata gcaatgtact taaactttat aaatacacat tgagtattta
    11341 tttaaaaagc acattgctat tttttaatta taattatctt aaaggtcaat taatattcgt
    11401 gttattactg gtataaactc tctactgtct ctgaattttt tgtcattctt ctttaagtat
    11461 aaataacaaa ttattgtaag acaaattcca actagtccac ttatagcttc aactccagtt
    11521 ttcagtccaa ttgcccccaa tatataataa gtccctattg ttcctacaag aagtgctata
    11581 agaggtatta tataagccat tacagctgct tttaatacat tcatattatc catactcact
    11641 tctacatggt caccaacttt tgcaccaatt gtgttgtcta cttctactaa tatttctttt
    11701 gactctgctg aatttgtagt agcacatttt ccacaagcag cacaagctga atgtctttgc
    11761 atttttaact ttgcagttct atcatcaaca atttccataa taaatccttg ttgattcata
    11821 actaaccgcc tccttatttt gtaaatttat ttatagtatc cataagctct tttatcatct
    11881 cttcagtttt atcagcatca tcatgtttga tactttctgc tacacatcct tttatatgat
    11941 tctctaagat aattgtgcct actctattta tagcagacct tatagcagat atttgaacca
    12001 atatatcaac acaataacgt tcttgttcga ccattttttg tatcccctta acttgacctt
    12061 ctattctttt taatcttttt atgagagctt ccctctcatt gtttggtgct aattttctct
    12121 cttccataaa ttcacctcat actctaatga tgtcttatgc aattatgctc tacttaccaa
    12181 cttgtttaaa atataataca gttattatta ctataaatac caaaattgat attgcaatag
    12241 acctgctttg attcttagtt tgttccatac ttaactttcc attcatctta aatcctgcca
    12301 atgggaataa aaatataacc agtgcatcaa ttccaagtac aacttgggct gcaatagtcc
    12361 atttgctcaa aaagcagaat attccaccca cacctaaaag aacctctaat atatttataa
    12421 acttatatgt aggttttttt gctatatatt cttcaatttt ttccttacat tctgcacgac
    12481 atggatatat attcgtattg tcatcatatt ttatagataa attattattt ggtgacttta
    12541 tatccctatt acagtaaaga cattttttca ttttatattc tcctctagta ttccttaaaa
    12601 aattttgcct aaattattat acgctataat actattatac caaatagata caaaaaacaa
    12661 aaataaaagg aataatttta gctatttctt ttatttcaat gtgtagtcta taataaattt
    12721 ataataacaa ttaaataata ttatttagtc taatttaatt gttatgtaat ttaaaataag
    12781 tcaaatttgt atgagaggtt aaaatgaaac aaatagaatt agctattgta agtttaaaaa
    12841 aagacgctgg agaaatttat gaaaatcaaa taaggcaatt cttaggtgat aatctaaaga
    12901 taaatttata ctcatttgaa gagggaaatt taaagttttt taaagaaaaa cttatactcc
    12961 tatctgctta cttaaaatat gatgaaatag taaaattatc tcactatgat gctcaaatca
    13021 ttgttcccaa gctgacattt gaaaagaaca gtattgatat gatatccaaa ttagaaaaag
    13081 ataaaattat ttatgtatat aacttaagta aagatatggc aatagaaaca atttctttaa
    13141 tacatagact aggaatagac aatatcaata tcctgccctg ctatccagag attgagttta
    13201 ctccctcaga tgctataatc ctaactcctg gtgaaaaaat cttgcctaag tttaaaaatt
    13261 gtgaagttat agatttaaaa tacagaataa tagatttaag ttgtattgtt gaaattgcta
    13321 caaaaaccaa attaaaacac ctaataaaag atgagctaat aaaaaaatac gtagaaaaaa
    13381 taattcctac aagttatagt acaggtgaat tattattaga tgcaaataaa tttgaaagac
    13441 aatttgatta aaaaatagct acgaacactt gtgactttag tcatgagtta gtagctaaat
    13501 tagtcagcat ataggaaaac ctatatgtag agataggata gaacctatcc aatactactt
    13561 gaattgctg
//
LOCUS       DAMKOJ010000087        13297 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000087 DAMKOJ010000000
VERSION     DAMKOJ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13297
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.094"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(52..2052)
                     /locus_tag="PC592_002926"
     CDS             complement(52..2052)
                     /locus_tag="PC592_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4056871.1"
                     /translation="MKQSIAIVTDKLTKLSSFLEENIRLVLGNYIDINHYYLEVLKED
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKEKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGVINTFNKKALKILGINENPQGKKIEDIISKDLNILLGDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMIKCIELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLPKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYISVEFANNYEDGFGYTKKEFKEILRILYERRESSSGVGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            complement(2083..3801)
                     /locus_tag="PC592_002927"
     CDS             complement(2083..3801)
                     /locus_tag="PC592_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4056872.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIVLFIKYDQNGLKEREIISKG
                     KYMSESLVADKSYDEAKKVVKTSFESIPAKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDAKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASILLKVGSYKTGEKLIKDSFKIDIDEGEKNGMVRLYALINLAEIYVEVGEY
                     DKAIEISSRVKDYKKFVNTDNYNDFEIMASIMQANAYIEKNNIQEAKNLLEKADYIIK
                     SDRTVHILDKDMYYYMAMGNLEYKNENYDSAIDNYKKSLDISTKRKLTQEKIKNLNKI
                     LNIYEKQGNVESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESELFEKTKKEIK
                     YYKILFTVILIAVLGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYRAKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDVVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIVDNIRVAIANKKWNEDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            complement(4020..5258)
                     /gene="fabF"
                     /locus_tag="PC592_002928"
     CDS             complement(4020..5258)
                     /gene="fabF"
                     /locus_tag="PC592_002928"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDF4056873.1"
                     /translation="MNKRVVITGLGCVTPLGTGREEFWSNIKAGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAVVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            complement(5287..5511)
                     /gene="acpP"
                     /locus_tag="PC592_002929"
     CDS             complement(5287..5511)
                     /gene="acpP"
                     /locus_tag="PC592_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF4056874.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            complement(5574..6323)
                     /gene="fabG"
                     /locus_tag="PC592_002930"
     CDS             complement(5574..6323)
                     /gene="fabG"
                     /locus_tag="PC592_002930"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDF4056875.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIENMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMASYITGQVINVDGGMVMQ"
     gene            complement(6323..7273)
                     /gene="fabD"
                     /locus_tag="PC592_002931"
     CDS             complement(6323..7273)
                     /gene="fabD"
                     /locus_tag="PC592_002931"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDF4056876.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAEIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPTGVGAMAAILGLDRNALESVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAIVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NMTKPKVDVVANVNADYYKNEGKELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            complement(7289..8218)
                     /gene="fabK"
                     /locus_tag="PC592_002932"
     CDS             complement(7289..8218)
                     /gene="fabK"
                     /locus_tag="PC592_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HDF4056877.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            complement(8327..9313)
                     /locus_tag="PC592_002933"
     CDS             complement(8327..9313)
                     /locus_tag="PC592_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDF4056878.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVSEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            complement(9339..10361)
                     /gene="plsX"
                     /locus_tag="PC592_002934"
     CDS             complement(9339..10361)
                     /gene="plsX"
                     /locus_tag="PC592_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDF4056879.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVSLNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDIKQFISKYNKEN
                     KNNEDE"
     gene            complement(10372..10929)
                     /gene="fapR"
                     /locus_tag="PC592_002935"
     CDS             complement(10372..10929)
                     /gene="fapR"
                     /locus_tag="PC592_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDF4056880.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            complement(11136..11312)
                     /gene="rpmF"
                     /locus_tag="PC592_002936"
     CDS             complement(11136..11312)
                     /gene="rpmF"
                     /locus_tag="PC592_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDF4056881.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            complement(11337..11861)
                     /locus_tag="PC592_002937"
     CDS             complement(11337..11861)
                     /locus_tag="PC592_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDF4056882.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            complement(11954..13150)
                     /locus_tag="PC592_002938"
     CDS             complement(11954..13150)
                     /locus_tag="PC592_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDF4056883.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEDALKECIDLAPLHNPANIMGIDACKAILPDVPMVAVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
BASE COUNT         3940 a         2633 c         1357 g         5367 t
ORIGIN      
        1 atttaaatat ctaaattcaa aatatgtaat ttcaatatca atatacttaa cttaatttat
       61 attattataa agttttatac cctctgaggt tatttgactt ccacctctac cagatttaga
      121 tgatatatat ccacattcac ttaaataaga tagcaccttt ctaactttgc tttcagaaat
      181 ctcaatccct tcctgtataa gcttttcaat tataaaccct cttccaactc cagaagacga
      241 ctctcttctt tcatatagaa tccttagtat ttccttaaat tctttttttg tatagccaaa
      301 tccatcttca taattattag caaattctac acttatatat ggtggtaagt catccctaaa
      361 aaccatacta tcacacatta gacttacgta agaagcaaca ttttgtaact ctcttatatt
      421 tcctggccaa ttatattttt ctaaaatagt tataacttct ggtgaaagtc ttatattatt
      481 tttcaaaaag aagttcataa gtgttattat atcttctttt ctattcctca atgatggcac
      541 atctattggt aatacattta atctataata caagtcttct ctaaattttc cttctctaat
      601 catctttggt aagtttttgt ttgttgctgc tatgacccta acatctatat ttataacatt
      661 atgggaacct ataggcataa cctgcttttc ttgtaatacc cttagtaact ttgtctgtag
      721 caatggaggc atatctccaa tttcatccag aaatatagtt ccattattag caagttcaaa
      781 taaccccttt ttcccttctc ttaaagctcc tgtaaaagag cctttttcat atccaaacag
      841 ttgactttct aatagactat ctggaactgc tgcacaatta actgctataa acggttgatt
      901 actcctatta gaagcattat gaattgattg cgataataat tctttaccag taccactttc
      961 tcctattatt agcacagaaa ggtctgattt agatattttt ttagccaatt ctatacactt
     1021 tatcatattt ttatttttag tttttatatc tttaaacgta tatcttgcta tctgcccttg
     1081 ttctcttaat ttattagtaa ggttttgttc taattttttt atatacgtta tttcttgcaa
     1141 gttataatat ataccagctt tattccccat agaaaaaata ctttttttat ttacatttat
     1201 atatttttta tttgtaaata caacttcatc aattatttct ttgtctccaa gtaaaatatt
     1261 taaatcttta gaaatgatat cttctatttt tttaccttgc ggattttcat ttatacctaa
     1321 aatttttaaa gcttttttat taaatgtgtt tattacacca tctgctgaag taaatattat
     1381 accatctttt gatagattca atataacatc ttgttcttct atttttaaaa acagttgtct
     1441 ataattatct ttaactccat tatctaaact tattaaactc tcagaatatg ccattaaatt
     1501 tttacgtatt tctttaacat caattctaag accatttatt atttctataa aggtagatat
     1561 atcgatatat ctattaccaa ggtcgattac tttatttata taacttggta ctttttcctt
     1621 tactccaggc gttatagcta tgtctatatt tttataaatt tttccttcaa tatatggagt
     1681 aaactttaaa ttttttactc ctattttata aaataaactt attgtttcta aggtagtttc
     1741 ctttgtatca tttacaacca atacttcagt tccatttggt attgaaaata atccatatat
     1801 ttcattttct ttaagggttc tccttatcac tataatctta ctatcttgta ctaaatgttt
     1861 tctcatactg tttaatctat catcattcat tactagtaca aaatcacctt gtattttatc
     1921 atcctctttc aaaacttcta gataataatg gtttatgtca atataatttc ctaaaaccaa
     1981 acgtatattt tcttctaaga aagatgatag tttagttaat ttatcagtta ctatagctat
     2041 tgattgtttc atacttatac ctcttattta tatagtatac agttacttat atactacttt
     2101 attcctacca agttgttttg ctttatataa atttttatca gcttcttcta gtacatcttt
     2161 gctatccgaa atatgagcta cacctgcact tatagtcaca gttacatctt cattccattt
     2221 tttatttgca attgcaactc ttatattgtc aactatatct gctacttctt caccagattt
     2281 atttcttatc aatacagaaa attcttctcc tccataccta aaaactttat catcttgttc
     2341 caacataaca caaatagtat ttgttatccc ttttataaca acatcaccaa atttatgtcc
     2401 ataattatca tttatgagtt tgaaattatc aatatctatc attacaagtg caaaattatc
     2461 atctttagct ctatactttt catacataat atcaaagctt tttctattat aaacatttgt
     2521 aagcccatca tgtaaatttt gtgctttaaa atacttcaat ctgttgtata aaaaagtaga
     2581 ccctaataca gcaattaaaa ttactgtaaa taatatttta taatatttta tttctttttt
     2641 agttttttca aatagctcac tttcatttga tactttatca attatataga aactagtctc
     2701 tgaatctctt atacttttgt tctctttata ttcatttatt aacatctttt gatactcatt
     2761 taaagattct acatttcctt gtttttcata tatatttaat atcttattta aattttttat
     2821 tttttcttgt gttagctttc ttttggttga tatatctaaa ctttttttat aattatctat
     2881 tgcagaatca taattttcat ttttatattc taaatttccc attgccatat aatagtacat
     2941 atctttatct aatatatgaa ctgttctatc tgattttata atataatcag ctttttctaa
     3001 aagattcttt gcctcttgta tattattttt ttctatataa gcatttgcct gcattataga
     3061 agccattatc tcaaaatcat tgtaattatc tgtatttaca aattttttat aatcttttac
     3121 tctgctactt atttcaatag ccttatcata ttctcctacc tctacatata tttctgccag
     3181 atttataaga gcatataatc tgaccattcc atttttttca ccttcatcaa tatctatttt
     3241 aaaagaatcc tttattaatt tttctcctgt tttataacta cctaccttta aaagtatgct
     3301 cgccaaatca acatctagtc ttgctttttc ataattattc cccaatttct cagccaattt
     3361 tatagacttt acagttaaat ctactgcttt agaataatta ttatccatta tatacactga
     3421 tgctaatctt ttttctatat taaacctgca ctcatcagat aattttgcat ctgattctct
     3481 catcttttct aaagaatcaa tgactatctt cgttccatct ggaacatatg aaatagtctt
     3541 taacatatcc caaacttcat tatatacttt attgtatttt tttgctggaa tagactcaaa
     3601 agaagtctta accacttttt ttgcttcatc atatgactta tctgccacaa gactttcaga
     3661 catatatttt cccttactta taatttctct ttctttcaat ccattttggt catactttat
     3721 aaataaaaca atactaataa gtattataca tataaaaatt atctttttag gtaacctttt
     3781 ctttggtagt ctaaaattca aaattttagt cctccttttg tatattgtag aatgaaaact
     3841 tgcatatata aataacctct taataaataa taatacaata tatcaaaatg atttacaaca
     3901 tatgctagac ttaaatctta ataaaaaagt ctcctaaaat aatttaggag actttaaatt
     3961 taatccaata taaatttata cagttaaaat aagtacttgt ttttttattt aatatttatt
     4021 tatacatatt tttttagtac tattgtagca ttatgcccac caaatcctaa agaatttgaa
     4081 agtgcatatc tgatattttt ttctttacct tgatttggaa cataatctaa atccaaatct
     4141 tcgccaactt cttgtatgtt tatagttgga ggaacaaaac tatcttctat actcatagca
     4201 caaacaacag cttctattgc acctgatgct cctaataagt gacccgtcat agattttgtt
     4261 gatgacacac ataaatcata tgccttttcc ccaaatacag tttttatagc catagtttcg
     4321 tataaatcat tgtaataagt tgaagtccca tgagcattta tataatcgac ttcctctagt
     4381 ggaacatttc catctttcaa agccatattc atagacctag ctgctccctc tccattttca
     4441 gctggagttg tcatatggta tgcatcagca gttaatccat atccaactac ttctgcatat
     4501 attttagcac ctcttgctaa agcatgttct aagtcttcta aaataacaat acctgctcct
     4561 tctcccatta caaaaccatc tctgtcttta tcaaatggtc ttgatgcagt tttagggtca
     4621 tcatttctag ttgacatagc cttcatatta cagaatccag caaaagcaag acctgttaca
     4681 gcagcttcag aacctcctgc taccataatg tctgcatcac ctctttgaat taccttaaaa
     4741 gcatcaccta ttgaatgagt tcctgatgca caagctgtac atacattagt gttaggtcct
     4801 tttgctccta aaaatattga aacttgacca gctgccatat ttcctatcat cataggtaca
     4861 aaaagtgaac ttactctttt atttcctttt tccaaaagaa ttttatgttg agtttctata
     4921 gcttcaactc cacctattcc agaacctatt ataacaccaa aacgttctct atcaacttta
     4981 tctaaatcaa gatttgcatc ttcaactgct aattttgcag atactactgc aaattgagca
     5041 aatttatcta atctcttcaa ttctttttta cttatatatt cttctggatg aaaattctta
     5101 acttctcctg ctatctgagt ttgatacgta ctagcatcaa aattagttat tttatctata
     5161 ccagatactc cagcttttat attactccag aactcttctc ttcccgttcc caacggtgta
     5221 acacatccaa gccctgttat tactactctt ttattcatcg gatacctcca cttttttaaa
     5281 gctcgactat ttattagctt ctatatactt aactatatct cctatagatt taaagttttc
     5341 tgcttctgta tctggtattt ctataccaaa ttcatcttca agtgccatta ttatttctac
     5401 tgcatctaat gaatctgctt ctaaatcctt cattaatgat gtctccatag ttatttcttt
     5461 atcttctact cctaattgct ctatgattat ttctacaact ttattaaaca ttgtgtacct
     5521 cctaaaattt ttattttaat agatttctct actttttaaa ttattatttt ttattattgc
     5581 attaccattc caccatctac atttattact tgtcctgtta tataacttgc catgtcacta
     5641 actaaaaatg ctacagcatt ggctacatct tctggtttac cataagattt ttttggtatg
     5701 tttgctagtg ttgattcttt tacatcatca cttagtactt tagtcatatc tgtttctata
     5761 aacccaggtg ctactgcatt tatatttatg tttcttgatg ctaattctct tgcagaagct
     5821 tttgtaaatc caattacacc tgcttttgat gcacaataat tagtttgccc tgcattcccc
     5881 ataattccaa ctactgaagt catatttatt attcttccat acttcttttt catcataggt
     5941 ttagtaactg cttttgtaca attaaagaca ccttttaagt ttatatctat aactctatca
     6001 aaatcttctt ctttcattct cataagcaag ccatctttag ttatgcctgc attattaacc
     6061 aatatatcaa tttttccaaa ttcgcttaca acagaatcta tcatttggtt cacttcatca
     6121 aatttagaca catcacattt tatagaagta cactttaccc ccatattttc tatttcattt
     6181 ttagttttta gtgcctcatc ttctttagaa gtataattga ttactacatc agctccaaaa
     6241 gatgctagtt tttttgctat ttcttttcct atacccctag agccaccagt aacaactgct
     6301 acttgtcctg taagatttat cattatatct ctccatttct ataattttgt acaaattcat
     6361 taagagaatc tataccatct atattataaa tattgacatt tgctttttta tttgaagcta
     6421 tcttcttaat aaatgctttt aaagtttttc caggtcccat ttctataaaa gtatcatatc
     6481 cgtcatttaa aagcctttct atagaatctt cccaaagaac agatgagctt acttgtttta
     6541 taagcagttc tttaccttca tttttatagt aatctgcatt tacatttgcc accacatcaa
     6601 ctttaggttt agtcatgtta actttttcta attcactagc cagttttact ccagcttctt
     6661 ttaacattga tgagtgaaaa ggtccactta catttaattt aactgccctt tttgctcctg
     6721 cttctttaca tttcactatt gcttcttcta tcttctcatt ttcaccagat ataactattt
     6781 gtccaggaga attgtaattt gctacttcta caataccacc ctgtatatct ttaaccacac
     6841 tttcaagtgc atttctatct agacctaaaa ttgctgccat agctccaaca cctgttggaa
     6901 ctgtttcctg cataaacttc cctctttttt taactaaaca tacagcatct ttaaagtcaa
     6961 ttgcatctgc tgcaaccaaa gcactatact ctcctaaaga taatcctaag catgcattat
     7021 attttaaatc tatttcagct tgtactgctt ttaatactgc tacactatgt gtaaccatag
     7081 caggttgagt gttttcagtt ttagaaagct cttcttcatt tccattaaac ataaggtttt
     7141 ttaagtccat gtttaaagca tcactggcct catctattac acttttagca acagtattat
     7201 tttcatataa atccttggcc atacctacat attgagctcc ttgaccaggg aatactagtg
     7261 caacttttcc catcttgctc ctcctgattt acagttctat tgctggcata atctctcttg
     7321 cttgatttac catagcttct ataatttcct tacaaggtgt tatttctttt accatagcag
     7381 cactttgacc tgccataaat gaaccttttt ctatgtctcc atctactgtt gcaaatctta
     7441 aagctcctgt acctttttta tctaattctt caggagtagc tccattttgt tccatcttta
     7501 aaaattcttt tgataattta ttttttaatg ttcttactgg atgaccagta cttcttcctg
     7561 ttacaattgc atctctatct tttgctttta gtactaggtt tttatagttt gaatgtacag
     7621 aacactcttc actacaaata aatctagttc ctacttgaac tgcactagca cctaatgcaa
     7681 atgatgcagc aattcctcta ccatctacaa ttcctccagc agctattaca ggtatgttta
     7741 cagcatcagc aacttgtgga actaagacca tagtagtaag ttctcctata tgtcctccac
     7801 cttcagtacc ttctgctatt actgctgtag ctcctagttt ttccattctt tgcgccaaag
     7861 ctattgtagg tactacagga ataacctttg ttccagcttc ctttaatcta tccatatact
     7921 ttgcaggatt tccagcacca gtagtaataa cttgaacttt ttcttctata attaaatcaa
     7981 ttatatcatc aacaaatggt gacataagca ttacatttac tccaaaaggc ttatcagtta
     8041 attttttaca ctcaacaatt tctttcttta tagcttcttt tggtgcgttt cctgctgcta
     8101 ttatgccaag ccctcctgca ttagatacag cacttgctaa tgatgcagta gctacccatg
     8161 ccattccccc ttggataact gggtatttta tatttaatat tttgcaaatt ttattcatac
     8221 aattctcctt cacttgaaat cataaaagta aactttttat tattaatcaa ctttattttg
     8281 tgcataagtt taattttgtt aattaaagca ttttagatat tttatactat aaagtccact
     8341 tgacaactga agccccccaa gttagacctc caccaaagcc aactaaaact acattatcac
     8401 cctttttaat tttaccttct ctataagctt catctaacgc tactgggata gatgcagcag
     8461 acatatttcc atatttgtct atattcacat aaactttttt catatcaagc tctaatctct
     8521 tagaggaagc ttgtatgatt cttatattag cctgatgtgg cactaaatag tctatatcag
     8581 ttgtatttaa atttgctttt tcaagagctc ttaaagaagt ttctgccatc tttctaactg
     8641 caaatttaaa tacatcacta cctgccattt ctattgtatg tagattagct tctacagtct
     8701 ctttacttgc cttaagtctt gaacctccag caggtacttt taaacaatct tttcctttac
     8761 catcagagcc catatgtgta gacagtattc caccttcact tacaggacca ataacagctg
     8821 ctccagctcc atctccaaat aatactgctg ttgttctatc atcataattt aaaaacttag
     8881 aacaagtttc tgcccctatt acaagcacat ttttatagca acctgtttcc acaaattgct
     8941 ttgcaatagt tactccatat acaaatccag aacaagctgc tgatatatca aatgcagtag
     9001 catttactgc tcctattgca tcttgtacta tacatgcagt tgaaggcaaa gacatatcag
     9061 gagtaattgt tgctaatata attagctcta tatcctctac gtttaacttt gcacattcta
     9121 tagcttttaa ggcagcttta gatgctaagt cagaagttgc ttcagactct ttggcaaatc
     9181 ttctttcctt aataccagtc ctagtactta tccactcatc tgatgtatcc attattttct
     9241 cgaagtgaaa attatcatat gattgctcag gtagataact tcctactcct aatattccag
     9301 cctttgtatt cattatatat taaacctcca aaacgagttt attcatcttc gttattttta
     9361 ttttctttat tgtatttgct tataaattgc ttaatatctt caacgacttt tccctttgaa
     9421 aattttattc cttgatttat agcatttttt atagctttag catcagaact accatgagct
     9481 tttataacgc ctccatttag acctaaaagt ggagctcccc catactcaga ataatctata
     9541 aaacttttta attttcttaa atcatccttt ataagtaatg ctcctatttt actttttgta
     9601 ctggccataa aagtttcctt tataagactc ataactgaaa gagctactcc ttcagcagat
     9661 ttaagtaata tattacctgt aaatccatca catatgatta tatctgtgta tgcatttata
     9721 acttctctag cttctacatt acctataaaa tttaaatcta attttttaat ttcttcatat
     9781 gaccttttga ctaaatcatt gcctttacct tcttctagtc caacatttgc taatgctacc
     9841 ttaggatttt caagacctaa aacttttctt gaataaatat tactcatagc tgcaaattca
     9901 actagattct taggtttaca atctgcattt gcgccacagt ctgctataag tgtcattcct
     9961 cgctttacat ttggtattgc tgaacataag caaggtctat caattccttt tattctacca
    10021 acaacaaata atccaccagc aagtaaggct cctgtatttc cagctgatat tatagcatct
    10081 gcctttcctt cttttacaag atttaatgat actaccatag acgaatcttt tttacttctt
    10141 atagccttta ctggtttatc ttcattttct ataatctcag tagtatgaac tatctctaat
    10201 ttatttctat caaattcata atttgaaaat tccttttcaa gtaaatcttt atctcctgtg
    10261 attattaaat caacttgata ttcttttata gcatttactg cgccttctac attagattta
    10321 ggtgcattat ctccacccat tccatcaatt actattttca taatttccct cctaatctaa
    10381 ttcttcaaag ataaactttc ctctaaatat ttgctcttgg gctttattat tgataacaac
    10441 ttttacataa tgctttttat ctatatttct atacacttct gcttttgcta taagcctatc
    10501 ttgttgttct atcaacttaa aactctttac atttgcaact ctcataataa ccttaggtgc
    10561 atctattata gccattgcca atgaatctgc tagagaaaaa atatacgtat cttttaaagt
    10621 attagtctta gagtaaatca tgtcctgtgt aacttctaac atagatatac ctaatcgccc
    10681 tacagataaa tcaatgattt ctcctgtaat ttcctttact cctaaagtct ttacttttga
    10741 actctgagtt tctgctattg atttgactct ttctcttagc tctggtatgt ttagactcat
    10801 tctatctaat cttatggtct gtatacttac atcaaacaga cttgataatt cttcatcagt
    10861 ataaaaagga tctgtcttta gcatatctat aagctctttt tgtctttggg ctttactttt
    10921 ctttttcatg ttccctccaa attttatagc tgtaattagt accagctact aatagtagta
    10981 tatagtaaca cacaaaaatt ttcaatactt atattattat ttttctattt tttaatatgc
    11041 ataaaatcca cttattttct ctagtaaatc atcttctttt tttatatgta caaaaaaaac
    11101 atgtagagta tactctacat gctttttaga agctattact tagacacaac ttctttacct
    11161 ttataatatc cacagtctgg acacactcta tgtggtaatt ttggctcatg acattgtggg
    11221 caacttacaa atcctgttgc ttccatcttt gagttagctg ctcttctcat ttttgtgttt
    11281 gatttagacg ttttacgctt tggtactgcc atttacgcca cctccttagt caaaatttaa
    11341 ttaaataaat cttttaattt agcaaaacga ggatctatgt attcctcatc gtttgtaatt
    11401 tcactgcaag aacactcttc ttcatttaag tttgccccgc atacttgaca aagaccttta
    11461 cagttttcac tacaaagaac tttatgaggt acattaaaat ctaatgtctg ttctattata
    11521 tcaataaggt cgatttcttc accatcgaat ataaaaggat caaattcctc aaactcatct
    11581 tcatcataat cttcttcttt tactaaaaaa ccttgtatag aatactctag tggtatttct
    11641 acttctttaa gacatcttga acaattgtca acaattgtaa aattgacatc tatatctaga
    11701 tacaaacctt tattagtctt tgacactttc ccttttaaat ttacaggtga tactaatttg
    11761 taaatctcat cacaataact aatagtatca attttttcac aaaaattcaa gtctattttg
    11821 tcagtttctt ttctatttat tttttctatg ctaactttca ttaagttcac ctcaacatat
    11881 caccaaattt attatacaaa tctagcattt gtttgtcaag tatttttact tgataggcat
    11941 aggtttaatt taattatttt accaatctta atgtatctct agctatcatt aattcttcat
    12001 tagttggtat taaaagcatt tttactttag aatcagcagt agatattact gtttcctttc
    12061 ctctaacatc attagcttct ttatctaatt tcattcctaa aaactccatg ttagaagcaa
    12121 tatctgctct tatagctttt ccattttcac caacgcctgc agtaaatact acgacatcca
    12181 atccattcat ttcagcagca taagctccta tatatttttg tactttttta acataagctt
    12241 ctaatgtcgc ttgagctctt tcgtctccat ttttagctgc atcttctata tctctgaagt
    12301 cactagaaat tccagtcatt ccatatactc cagattcttt attcattaat ttatccaatc
    12361 catcagcatc taaaccttct tttctcatta agaaaggtaa tatagctggg tctatatctc
    12421 cacatctagt tcccattatt aacccttcta atggagtgaa tcccatagat gtatctacac
    12481 attttccacc atcaacagca gctatagaag caccatttcc taagtggcaa gttactattt
    12541 ttaaatcttt tatatctttt cctaatatct ctgctgctct ttgagataca taattgtgag
    12601 aagttccatg gaatccatat cttcttaccc catatttagt atataactca tgaggtaaac
    12661 catataagta tgaagattta ggcattgttt gatggaaagc agtatcaaat acagctacca
    12721 ttggtacatc tggaagtata gctttacaag catctattcc cattatgttt gctggattat
    12781 gaagtggagc taaatctata cattctttta aagcatcttc tacttctgga gttattacta
    12841 ctgaagttgc aaatttttct ccagcatgta caactctatg tcctactgca tctatttctt
    12901 tcatctcttt aactgcacca aattccggat gagcaacagc ctctaaaact aatgctattg
    12961 catctttgtg gtccttcatt ggctgttcaa caacgtattt atcatctcta cctgcttttt
    13021 catgttttaa tatagaacct tctattccta ttctctcaac caatcctata cataaaactt
    13081 cttcattatt catatctatt aattgatatt ttaatgaaga actcccacag tttaatacta
    13141 atattttcat tattatttcc tccttagatt tttttataaa taatatgtaa taaattttga
    13201 tttgtaataa atgtctaaat aaaactctat cttttattat tttgtcatag atatattatt
    13261 gtatacatta aacgattttc ataaataata tatcacc
//
LOCUS       DAMKOJ010000088        13105 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000088 DAMKOJ010000000
VERSION     DAMKOJ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.095"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            227..1645
                     /locus_tag="PC592_002939"
     CDS             227..1645
                     /locus_tag="PC592_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF4056884.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GIFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIVPMVIKQIVFGLAIGFVLAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYIGGNGYLSVYISGIIIGNSKIPHKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNIFGIAMVISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVIIENDIFHIIFFIALLSVGVQGTLIPAVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDDSSKWANKSIMDSNIPEDILIVMIKRKEQVLVPKGS
                     TVIKTGDTLVLSGDRIEELIQL"
     gene            1721..2533
                     /locus_tag="PC592_002940"
     CDS             1721..2533
                     /locus_tag="PC592_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4056885.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKEAIENPEEVENILKNKEKEMLDVIKSEEYKLIKLRN
                     YLVNLKGEVNMNDVIIKSLPKVKIASMRKVLKGYDELFNLFPNVMAEEMMKSECTCAV
                     PDYCFNIYHDGEYRETNMDVEMCQAINDLKEDTDILKFKELDEVESAVCILHNGSYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRIL"
     gene            2941..3558
                     /locus_tag="PC592_002941"
     CDS             2941..3558
                     /locus_tag="PC592_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDF4056886.1"
                     /translation="MEIFAIGHSNYPYDKLIDMIKKYDINCVVDIRETPYSKYNTQYN
                     KEAFNESLRNSGFVYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLKGIDRLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKILNKEGFDVKYIMHEGNLAYQQDIEESLLD
                     KYFADRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(3714..4166)
                     /locus_tag="PC592_002942"
     CDS             complement(3714..4166)
                     /locus_tag="PC592_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056887.1"
                     /translation="MVNLNENNLNVNMVYPISPTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTIGLGTMNIDKVYGQWAWFTDTIYDLNLFVFVGNYPYQIAKNRYDTFVNILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            4450..5808
                     /locus_tag="PC592_002943"
     CDS             4450..5808
                     /locus_tag="PC592_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4056888.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDNEKVNETIKQALVSGAILSFTITILM
                     WIFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIAIQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGVDLNPLGINLQTPSYGITGAAMSIAIARIIGCIVIVRAL
                     FKGNEFISIGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFVV
                     GAIFVPIAPWISSLYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     IA"
     gene            6081..6461
                     /locus_tag="PC592_002944"
     CDS             6081..6461
                     /locus_tag="PC592_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF4056889.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRIFSFKDQDGNDYLVREDK"
     gene            6586..6786
                     /locus_tag="PC592_002945"
     CDS             6586..6786
                     /locus_tag="PC592_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056890.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            6982..7710
                     /locus_tag="PC592_002946"
     CDS             6982..7710
                     /locus_tag="PC592_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4056891.1"
                     /translation="MLEIKNLSFNVESNSEELGIINDVSLSFEKGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESDQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            7732..8649
                     /locus_tag="PC592_002947"
     CDS             7732..8649
                     /locus_tag="PC592_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HDF4056892.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTDTGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGKGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVVLEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            8786..9970
                     /locus_tag="PC592_002948"
     CDS             8786..9970
                     /locus_tag="PC592_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF4056893.1"
                     /translation="MKNLLIRNGTIISPTDGIKFERRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPLNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNKNGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKKSGTLRKSVINAKDRGVLFDVCHGLDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHENKGRI
                     RIGGDGDFTIFTMEKSNDIIKDYNNNELILNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            10077..10265
                     /locus_tag="PC592_002949"
     CDS             10077..10265
                     /locus_tag="PC592_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF4056894.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            10415..11065
                     /locus_tag="PC592_002950"
     CDS             10415..11065
                     /locus_tag="PC592_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF4056895.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIEEDLENLE
                     QFIGPPLYDTFKEYYKFEDKKAKEAVEKYREYFTDKGIFENKIYENIKEILEMLYKKG
                     KILLVATSKPTVFAETILRYFDIDRYFKYVAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYLVENVESIKDILL"
     gene            11168..12106
                     /locus_tag="PC592_002951"
     CDS             11168..12106
                     /locus_tag="PC592_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF4056896.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYKGFK
                     KHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDSLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFVINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEVIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            12132..12983
                     /locus_tag="PC592_002952"
     CDS             12132..12983
                     /locus_tag="PC592_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF4056897.1"
                     /translation="MNSKIKYFLKFFILIFILIFVYSVAIEPSLLIVKKYNISENGTL
                     IKNDIIESKSESIKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPNVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSDFNLLVNENKKIK
                     LKDNKYINILGVDEILNGHPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKYTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
BASE COUNT         5241 a         1266 c         2313 g         4285 t
ORIGIN      
        1 aatgaaatat taataaaaaa aaattcaaat tataactatt aaatgaatat aattaaaata
       61 aatatataaa tttaagtata acactcatat tttaatgtat tgtgaaattt ttattgtact
      121 ttatacacta taacttataa aacctatgtc atattatatt tgaataagta ataaaattgt
      181 agatgtaaat taatctacaa aatttatatg aaatggagtt gatgctatga cagaattaat
      241 gattataagt gggttagtac tattgatttg tataacttct agcaaggtat tgtataaatt
      301 tggagtacca atattattga tttttatctt actagggatg ttatttgggt ctgatggaat
      361 ggtaggaatc tattttgata actatgaatt aacaaaacaa ttatgctcta ttggactaat
      421 attcataatg ttttttggag ggtttggaac aaactggaat atggctaaac ctgttgctat
      481 accttctata ttgatgtctt cactgggtgt aataattacg gctggggtta caggcatatt
      541 ttgccatatg gtaataggaa ctagtttact tgaaggttta ttaattgggg caattgcagc
      601 ttcaacagat gctgcatctg tgtttgctgt gttgcgttct caaaaattaa acttaaaggg
      661 ttcacttgcc tcattattag aagttgaaag tggaagtaat gacccaatag cgtatatgtt
      721 gacactaatt cttttgacat tgatgaacaa ttctggtgta gagcttattg taccaatggt
      781 aataaaacaa atagtttttg ggttagctat aggatttgta ctagcaaaat tatctgttta
      841 tattttaagg cattcaaact tcgagataga aggattttat actatattta taacagctat
      901 tgcaatactt tcgtatgcat ttagtgagta tatcggagga aatggatatt taagtgtgta
      961 tatttcaggt attattatag gaaatagcaa gatacctcat aaaaaaagtt tggttcattt
     1021 ctttgatgga atttcatgga ttatgcagat aatgttattc tttatgttag gattgttatc
     1081 tttcccttcc aagctaccaa atatatttgg tatagcaatg gtcatatcta tattcatgat
     1141 agttattgca agaccattag caacatttat agtactagca aaatttaaat tttcaaataa
     1201 agaaaaacta ttcatatcat gggtaggtct tagaggtgca gcctcagtag tttttgcaat
     1261 ttatgcagtt actcaaggtg taataataga gaatgatata ttccatataa tattttttat
     1321 agctttactt tcagtagggg tacaaggtac attgatacca gcagtagcta gaaagctaga
     1381 tttagttgat gataatacac ctgtattaaa aacatttaat gattatgatg gagaaattag
     1441 ctctaaactt atagaagtaa atgttgatga tagtagtaag tgggcaaata agagtataat
     1501 ggattctaat ataccagaag atatattaat agttatgata aaacgaaagg aacaggtttt
     1561 agtgcctaaa ggctcaactg ttataaaaac aggggatacg ttggtattaa gtggagatag
     1621 aattgaagaa ttaatacaat tataatttat ttcgtattga ctttaaccta aggggaaggt
     1681 ctaaacttaa attaatcaaa tctaatgcgc aggtgatgag atgttttcta taggaatgtt
     1741 ttctaaaata aataaaataa ctacaaagac attaaggtat tatgaagata tagggttgtt
     1801 aaaaccagag tatgtagatg agtttacaaa atataggtac tatacgacag agcaattacc
     1861 taaattacat cagataataa ctttaaaaca aatgggtttg tcattagctg agataaaaga
     1921 agctatagaa aatcctgaag aggttgaaaa tattttaaag aataaagaaa aagaaatgtt
     1981 agatgtaatt aaaagtgaag aatataaact cattaaactg cgtaattacc ttgtgaattt
     2041 gaaaggagaa gtcaatatga atgatgtaat tattaagtct ttaccaaaag ttaaaattgc
     2101 ctctatgaga aaggtattaa aggggtatga tgaacttttt aatctatttc caaatgtaat
     2161 ggctgaagaa atgatgaagt cagagtgtac atgtgcagtt ccagattatt gtttcaatat
     2221 atatcatgat ggtgaataca gagagaccaa tatggatgtt gagatgtgtc aagctataaa
     2281 tgatttaaaa gaagatacag atatattaaa atttaaagaa ctagatgaag ttgaaagtgc
     2341 tgtttgtata ttacacaatg gttcatattc aacattggga aaaacttacg cagatgcatt
     2401 taaatggata gaggataata aatataaagt ggttggaaat cccagagaat cttatataga
     2461 tggtatatgg aataaagaga gtgaagaaga ttggttgaca gaagttcaga taccagtgaa
     2521 acgcatatta taatatgtat acaaagtata aataagaata aaaaagtggt gtctcaaaat
     2581 gaatttttta gtttatgagg cacctttttt catatgaaat caagtatatt tttataattt
     2641 caatgatgaa aaaaagctta tctctatttt gagacagcct cttatttttt tattataata
     2701 gttttctaaa gatgttctat ttattaaatt tttataaata attatattta atatacaaaa
     2761 tatgcataaa tcttgatgtt ttatatataa agttgtatat tttttaagga tataaagtaa
     2821 aaagtgtaaa gtatcaagaa aaaatctatt gggtatttaa agtaatgctt tatttaattt
     2881 taaataaatc gggtatacat atatataaat actaatttta aagaatagga ggatatttat
     2941 atggaaatat tcgcaatagg acattcaaat tatccatatg ataagcttat tgatatgata
     3001 aaaaaatatg acataaattg tgtagttgac attagagaaa ctccatattc taaatataat
     3061 actcaataca ataaagaggc attcaacgaa tctcttagaa attcaggatt tgtatatata
     3121 tacatgggaa aagaatttgg agctaaaaga actaataaag atgtatatac acaagaaggt
     3181 tatgcagatt ttgagaaagt agcaaaagaa gatatttttt taaaaggaat agatagatta
     3241 aaaaaaggtt gtcaaatggg ttataggata gttttattag gagctatgca agaacctata
     3301 agatgccata gaagtatttt ggtaggaaaa atattaaata aagaaggttt tgatgtaaaa
     3361 tatataatgc atgaaggaaa tttggcatat cagcaagata tagaggaatc attattggat
     3421 aagtattttg ctgatagaaa gcaactgagt attgacaatt tattagggag tgcattaaca
     3481 agagaagaaa tgatacaaga aggctataaa ctggctaata aagaaatagg atatagaact
     3541 gagaaactag gtaaataaaa atagataagt agataaaaca cagtacttat cttaaaaaaa
     3601 taatattatg aatttataat agctaagcat gatgtgccaa ttaaaaatat tctagttatt
     3661 taatagtatc attaaattta ggatattttt taatagcaca tcatgttgta gtgttaaaaa
     3721 ataaaatctc taatattgcc ataatcaact gttctattaa gagtaggatg actagatata
     3781 aatctaactg taatttttga atttaacaga caaggatttg aaattaaaaa tactctatct
     3841 ccattgacaa tagaagtaat agccactggt aaaatattta caaatgtatc atatctgttt
     3901 ttggcaattt gataaggata atttcctaca aaaacaaata gattcaaatc atatatagta
     3961 tcagtaaacc aagcccactg accataaact ttgtcgatat tcattgtgcc taaaccaatc
     4021 gtatcaaagt atgttgctat agttaaataa atattttcca tgttttctaa atatgaaaca
     4081 gtatatcttc tgaaacgtat gggtgctgtg ggagaaatag gataaaccat atttacattt
     4141 agattatttt catttaaatt aaccaaagta tcacatccta aaattagttt ataaaataca
     4201 atatttaaat ggagacgatt ttgttacatc taaatgtaat attttaaatg tggtagccat
     4261 aaaaaataat aaacatagaa taattataaa gatatacggt gttcaaatta tattaaacaa
     4321 gatttatatt atttgaaagc aatatattat gatgctaata atacaatttt aaactttgta
     4381 ttatcaattt acagttcgat aaactaatta aaaattaaat ttatataaag agggaaaaga
     4441 ggaataggga tgtttataag gaaaaatgtt ataaagttag caattcctat aatgatagag
     4501 cagacgtttg tcatgctttt aggggtattt aatacaatga tggcaggtca tattggggaa
     4561 gaagctgtat ctgcagttgg aatggttgat tcaataaaca atatatttat atctgtattt
     4621 gctgcattat ctgttggagc tactgttgtt gtagctcaac aaatagggaa aaaagataat
     4681 gaaaaagtga atgaaactat taagcaggct ctagtgtctg gagcaatatt atcctttaca
     4741 ataacaatat taatgtggat ttttagaaca ggtgtaatta atttatttta tggttcagca
     4801 gaagaattgg taaaatcaaa tgcaaaatta tacatagagt ttacattgtt tacataccca
     4861 ttcattgcga tacaacaaat agcaaatggt attctaaggg gttgtggaga tgtaaagaaa
     4921 cctatgtatg tgactatgtt tatgaatata gtaaatgtaa cattaggata tatacttata
     4981 tatggtgttg atttaaatcc tctaggaata aatttacaaa caccatccta tgggataaca
     5041 ggtgcagcta tgtctattgc catagccaga ataattggat gtatagttat tgtaagagcc
     5101 ttatttaaag gaaatgaatt tatatctata ggtaaaatat ttccatttaa gattgatgtt
     5161 gaaactcaaa agtctatatt taatataggg ataccagctg gagttgaaca actacttttt
     5221 aatgcaggta aattgattgt tcaggtattt atagttacta tgggaacatc agcaattgca
     5281 tccaatgcaa taggaatgtc aattgcatcc ataataaatg taattgggaa tgctctagct
     5341 ttgtctgcca caactttggt gggacagtat ataggacgtg gagatattaa aggagctaag
     5401 agtactttat tatatttaac taaatttgca acaatttgtt tatttgtagt aggagctata
     5461 tttgtaccaa ttgcaccttg gatttcaagt ttgtatactc aaaatgctag tgtaattgac
     5521 atttcaacac aattaattcg aagtgattgt ttagctatgg taatatggcc tatatccttt
     5581 gtattatcag cagggctaaa gggggctggt gatactagat atacaatgat gactgcagta
     5641 ataggtatgt ggatttttag aatttttaca ggttacgtat tgggggttgt attagaattt
     5701 ggagtgttag gaatttggat aggtatgtat actgattggc ttgtaagagg aactttatat
     5761 tgtttaagat taagaggaac aaagtggcta aaacacaaaa ttgcatagaa tatatgaaat
     5821 cacttttaga tagaaaactc tatttaggag tgatttttta tgtaattatt atcataatta
     5881 taagtatgat atataaggtg attaaattgc ataaataaag cctataataa tatggatact
     5941 ataaattata tattgagcag aattacataa tttggtgata aatattagaa atatatatct
     6001 atagaaaata atatatatgg gtatattatt aaatataaaa aatattaggt atttatttaa
     6061 taataaaggt gggtattgtt atgataaata aaataggaaa aataactctc tatgtaaata
     6121 atcaagagga tgcaaagttg ttttggacag aaaaattgaa ctttgtggta acttatgaaa
     6181 aggaaatggg tccaaatatg aaatgggtag aagttgcacc aagtaaaaat gaatttacaa
     6241 catttgtgtt gtatgataaa aatctaatga tgaagcaaaa caaagagata aatgtatctc
     6301 atccatcaat aattttaagt acaagagaca ttaatggaac ttatgaacaa atggcaaata
     6361 acgaggttga ggttggagaa ttaatggaaa tgccatatgg aaggatattt tcttttaaag
     6421 accaagatgg aaatgactat ttggtcagag aggataaata attttacaaa gtattaaatt
     6481 tactcaatat ctgatataat tagagacaat aattattata aactagtcca gaattagagt
     6541 tatataatta aaaattaagt gtaaattttg agtagaggtg ataaaatgtt taagaaaatg
     6601 gcagtactaa aagatatagc aactaaaata ggtcgtaaaa aggcttatga actattagaa
     6661 atggttgaag gtaatgatgc ctttgtagct gaggtaaaga taaaaaagaa tggaatagaa
     6721 tctaaaaaag aagaaattat gttaaaagat aatcaaaaaa taatattaga gtatatagaa
     6781 ggttaatttt taaatatata taagatgata tactaaattt ctaagatgag tttgcataaa
     6841 actcatcttt tttacttttc aataaatttg ttttattatt taatacacat tttatctgct
     6901 tagagttgct gatatataaa aattactgat ataataaaag aatggatatt aatgtaatat
     6961 tttacagaaa agaggggtat tatgcttgaa ataaaaaatc tttcctttaa tgttgagtct
     7021 aacagtgagg aactaggaat aataaatgat gttagccttt catttgagaa gggaaaactt
     7081 attgttatca cagggccaaa tggtggagga aaatctacaa ttgctaagct tattatggga
     7141 attgaaaaag ctactagtgg tcagataatt ttagatggag aagatataac aaatcttagt
     7201 attacagaaa gagcaaaaaa aggaatagga tatgcatttc aacagccacc aagaataaaa
     7261 ggtatgacag ttgaaaattt acttacactt gctcatggaa aaccattgtc tactgatgta
     7321 tgttgccaat accttacaga tgttggattg tgttcaaaag actatttaaa tcgtgaagtt
     7381 gataactctc tttctggggg agaaatgaaa agaattgaga tagcaactct ttttgctaga
     7441 gatttaaagg tttctatatt tgatgaacct gaagcaggaa tagacctttg gagctttggc
     7501 aaactcaatg aaagctttaa gaaaatacat gaagagtctg accagactat aattataatt
     7561 tctcaccaag aaagaatatt agagttagct gatgaaataa ttgttctaca agatggttca
     7621 gtaaaaagcc atggaacaaa agaggctata ttacctgaaa tcatgtgtca agttaattca
     7681 agctgtgaat taatgaaaga tatgaattaa ttagaaagga aggcaaatta aatgaacaaa
     7741 atagatttaa atcttttaga aaaagttgct gaacttcgtg gaactccatt aggagcatac
     7801 aatatacgta aaaatgggca aggagtagag agacattcaa ctgaaaatgt aactataatt
     7861 cctaaaactg ataaacctgg aatagatatt atagtaaagc caaatacaaa aggagaaaat
     7921 gtacatatac cagtaatagt aacagatact ggtgtacagg atatggtata taatgacttt
     7981 gaaattggag aaaatgcaga tgttgttata attgctggat gtggtataca taactgtggt
     8041 tgtgacgata gtgaacataa tggtatacat agatttttct tacgtaaagg agctcgccta
     8101 aaatatgtag aaaaacatta tggtgaaggt gatggtaaag gaaagagaat tttaaatcca
     8161 gttactattg ttaatatgga tgaggattca tattgtgaga tggaaacaat tcaaattaag
     8221 ggtgtagatt caactaaaag agaaatggat gctaacctag gtaaaggagc taaaatagtt
     8281 gtatttgaga aattattaac tcatggtaat caagttgcag aatctaatat gaaggttgtc
     8341 ttagaggggg aaaactcttc tgctcaagta gtttctcgta cagttgggca agataattct
     8401 aagcaaaaat ttaatccttg tgttattggg gattctcttt gttctgcaca tgttcaatgt
     8461 gattcaataa ttatgggaaa ttctcaaatt agtgctatac ctgaaattgc tgcaaatcac
     8521 ccagatgctc ttttagtaca tgaagcagct attggaaaga ttgcaggaga ccaaatacta
     8581 aagatgatga cattaggtct tactgaagaa gaagccgagc aacaaatact taattgcttc
     8641 ttaaagtaaa ttaaagtttt tatttaattt aattaatata gtataatata gtgaataagt
     8701 ctaaaatatt tttattttta ggcttatttt atttatgtaa gaaaaactat tagataaatt
     8761 atattgtaat taggatgtgg aataaatgaa aaatttactt ataagaaatg ggacaataat
     8821 atctccaaca gatggtatca aatttgaaag aagagatatc ctggttttac atgggaaaat
     8881 atatgctatt ggattgaacc ttaaagaaaa aataagaaaa gaaaaattac ttacaaataa
     8941 agagttcgag ataataaatg ctgataatat gtatatttcc ccaggattta tagatgttca
     9001 cacccattgt tataagagaa aattacctac aggtatggat tctgattcaa ttggaattga
     9061 aaaaggttct acagttatat ttgatgcagg tacagctggt cctttaaact actatgattt
     9121 taaaaaaaag tatatggatg agtgtaaaac agaagtatat tcttttttaa atgttacaaa
     9181 tgagggacta aatatattga atgaatcaac ttctttagat gttataaatt ttgacaaggt
     9241 tgagtcagtt gtagaaaaaa atatagaaaa gataaagggg ataaaagtaa aagcgagtaa
     9301 atttcaatct aataaaaatg gtatagatat aattaagaaa tcaaagcaag ttgctaagaa
     9361 attaaactta cccttagtag tatatatagg tgagtatcca tcatatatag atgaagtaat
     9421 gaatattttg ggaaaaggag atgtggttac accagtatat gggaatagta caaatggaat
     9481 ccttaaaaaa tctggtacat taagaaaatc agtaataaac gcaaaggata gaggagtatt
     9541 gtttgatgta tgtcatggat tagaccaatt tgattttaaa gtatttaaaa aagcaataaa
     9601 gcaaggttta gagccagacc taataagtac tgatatgcat ataaaaaaca tgaaagacgt
     9661 aaattattct cttttaaatg ttataaataa aattatggaa cttggcatat ccttagaaaa
     9721 gtgcatagaa aaagtaactg aatatccaac aaaaattttc gatttacatg aaaataaagg
     9781 aagaataagg attggtggag acggtgattt tacaatattc acaatggaaa agagtaatga
     9841 tataataaaa gactataata ataatgaact cattttaaat aaaaaattaa gattacaata
     9901 tactgtaaaa tcatggatga aaagcagtga agtttataga catggatacg aaaatactat
     9961 aataaattaa acaatagtga taaaataata aatatatgtt taaattgtca tatattggat
    10021 aaatatctaa ggaaacaaca attaaaaaat aataatttta ggggaggtat tttagtatga
    10081 aagcatttgt tgataaggat gtatgtgtag cttgtggagc atgtatagga acatgtccag
    10141 acgtttttag tatgagtgat gaagggcatt cagtagcaat tgaaggagaa ataccagcag
    10201 acttacaaga tttatgtaaa gaagccgaag aaggatgtcc agtttcagct ataacagtta
    10261 aatagagttg tttaaattta ttttaaaaat aaatatataa gatttaattg agtacttaag
    10321 ctatagtatt agaaatttct attactatag ctttttaaaa tagataaact taaaatatag
    10381 ggtattattt tttataagta tggaggactg aaatatgaag aaaaattatg aaatagtatt
    10441 atttgattta gatggaacac ttacagaccc taaagaagga ataacaaagt ctattcagta
    10501 ttctttaaat agttttggta ttgaagaaga tttggaaaac ttagaacaat ttataggacc
    10561 accattatac gatactttta aagagtatta taaatttgaa gataaaaaag ctaaagaagc
    10621 tgttgaaaag tatagagaat attttactga taaagggata tttgaaaata aaatctatga
    10681 gaatataaaa gagatattag aaatgctcta taaaaaaggt aaaatattat tagtagcaac
    10741 ttctaagcca acggtttttg cagaaactat acttagatat tttgatatag atagatattt
    10801 taaatatgta gcaggtagca atcttgatgg tacaagagta aataaaaatg aagttataca
    10861 atatgtacta gacctatgta atgtaaaaga taaagataaa gttattatgg ttggagatag
    10921 aaagtatgac ataattggag ctaaaaaaat aggcatagat tctattggag tgttgtatgg
    10981 gtatggttct tttgaagagc ttagtgaaag tgaacctact tatcttgtcg aaaatgtaga
    11041 gtctataaaa gatattttgt tataaatatc ttttatagac aaaaatatta caaaatggtg
    11101 tcgcatattt aaaaatatga tattatagtt aaggaagtca tttaaaaaag aggaggatgc
    11161 acttaaaatg aaatctattt taattatggg tggaagcgac ttcataggtt ctgcacttgc
    11221 taagcgtttg attaaatgtg ggtatcaaat tgatatactt acaaatggta aaaaggaaat
    11281 agattataag ggttttaaaa aacatctaat ttgtgataga aaagttcgaa aagatatgga
    11341 aaacattatc acaggaagaa aatatgatta catatatgat atgacagcat atacaaaaga
    11401 agatgtaagt aatctgattg attttataag tatggatagc ttaaaaaagt atatagtatt
    11461 gtcagcagga gcagtatata aagatagtgg aagaaatata aaagaagaaa atgagaaagg
    11521 tgaaaatgaa aactggggaa aatatgggtt aaataaaaaa gaggctgaag attttgttat
    11581 aaatagccct ataccatata taattattag accaacttac atatatggtg aaaataataa
    11641 tttatataga gagtattatt tctttgaaaa aatagaaaaa aatgaaaaga taccagtacc
    11701 aaaaggaaaa caagttagta atcaatttat atatattgga gatttggtaa aggtattaga
    11761 aagtataatg aaaaatcctc atgtaagaga ggcatataat gtgacgaatc cacagttaat
    11821 ttcttgggat gaccttatat atacgtgtgg agaagttatt ggcaaagaac ctataataaa
    11881 atatgtagat atggaaaaag tagagtttag agaaagaacg tatttcccat ttagaaatat
    11941 agactttaat cttgatataa ataagcttat tgaacatggg ctttatatac caaatgtgtt
    12001 actaaaagaa ggtcttacag caacatataa gtggttttca gcaaataagc caaaaatgca
    12061 tgacagaaaa atgaacaaag ttgagtctgt aatgcaaata gtttaaaaaa ataaataagt
    12121 aggtagatat tttgaactca aaaattaagt attttttaaa attttttatc ttaatattta
    12181 ttttgatttt tgtatactca gttgcaatag agccgagtct attaattgtg aaaaaatata
    12241 atataagtga aaatggaaca ttgataaaaa atgatataat tgagagtaaa tctgaaagta
    12301 taaaagtagt tcaaatttca gatactcaaa taggaagttt ttactcaact aagaatctca
    12361 aaaaagtggc taataagatt aatactttga atccagatat aatagtattt actggtgatt
    12421 tgattgatta ctccaataaa aatccaaatg tagatgaaat tacaactatt ttatcaagta
    12481 tgaatgctag gttgggaaaa ttttcagtat tcggtaatca tgattatatg tataaacttc
    12541 ctaggtatta taggcagatt atgaaaaatt ccgactttaa tcttttagta aatgaaaata
    12601 aaaaaataaa attaaaagat aataagtata ttaatatatt aggtgttgat gaaatattaa
    12661 atggacatcc taatataaaa tatctggaga gtcaaataga taataagaat tttaatttat
    12721 tgttagcaca tgaaccagat ttagtagaca tgcttagtaa atatacaatg aatttagttt
    12781 tatctgggca tagtcatggt ggtcaaataa gactacctat taagggagca ttagttactc
    12841 ctccatatgg aagaaaatat actaaagggt tttatgatat aaatggaaat catttatatg
    12901 tgagttcagg tcttggaagc acaaagttac catttagatt ttttaatata ccagagataa
    12961 tagaatttaa tattataatc taacataaaa tatttagaaa atatcatttt gtttgttata
    13021 atatgtaaat gtatatactg taaaaataga ttaaactagt agattgaatg aattaataga
    13081 ttaaattaat atataaaata tttaa
//
LOCUS       DAMKOJ010000089        13040 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000089 DAMKOJ010000000
VERSION     DAMKOJ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.096"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            70..1863
                     /locus_tag="PC592_002953"
     CDS             70..1863
                     /locus_tag="PC592_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF4056898.1"
                     /translation="MTIKDRLSGLRKLMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDGIWTDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYSDVYEFVKNIDKAEKVLVDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEIELENIRNSHIKDGVAFTKFMYWLKQNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKVKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(1945..3327)
                     /locus_tag="PC592_002954"
     CDS             complement(1945..3327)
                     /locus_tag="PC592_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF4056899.1"
                     /translation="MSVLKTQEKLKQPKDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLSWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGASISMYGYRYVFLFSSITVLIGLFFFVFGNRKFYNSLN
                     NNHSNERESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVMQTGTDSNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISLLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSS"
     gene            3585..3932
                     /locus_tag="PC592_002955"
     CDS             3585..3932
                     /locus_tag="PC592_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF4056900.1"
                     /translation="MIRKKSELQVEVKENLNGGIGNVKLENIIQNEELKGKGRLFKRV
                     SLPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            3950..4984
                     /locus_tag="PC592_002956"
     CDS             3950..4984
                     /locus_tag="PC592_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056901.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKEINSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLNESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARGKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(5033..6082)
                     /locus_tag="PC592_002957"
     CDS             complement(5033..6082)
                     /locus_tag="PC592_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4056902.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEIGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MIGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSVGKGGTSMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            6357..7892
                     /locus_tag="PC592_002958"
     CDS             6357..7892
                     /locus_tag="PC592_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056903.1"
                     /translation="MRFIKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKDPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNRVSAVGVGKATIYAKCGNKEVERTFRIEARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPIERAISLSSNGNIVGL
                     REGKDRVRITCGDKSKIITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNVDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMKVESISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNNSQNSDVI
                     NVR"
     gene            complement(8039..8389)
                     /locus_tag="PC592_002959"
                     /pseudo
     CDS             complement(8039..8389)
                     /locus_tag="PC592_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
     gene            8391..9452
                     /locus_tag="PC592_002960"
                     /pseudo
     CDS             8391..9452
                     /locus_tag="PC592_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
     gene            9853..11121
                     /gene="eam"
                     /locus_tag="PC592_002961"
     CDS             9853..11121
                     /gene="eam"
                     /locus_tag="PC592_002961"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF4056904.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEHIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTYIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPIYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(11214..11570)
                     /locus_tag="PC592_002962"
     CDS             complement(11214..11570)
                     /locus_tag="PC592_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056905.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(11721..12815)
                     /locus_tag="PC592_002963"
     CDS             complement(11721..12815)
                     /locus_tag="PC592_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF4056906.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTIMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTTALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         5161 a         1612 c         2061 g         4206 t
ORIGIN      
        1 atttatgtaa taaactttac atacttatat atttagttat tcaaactatt atttttagga
       61 ggtcttgttg tgactataaa agatagatta agtggattaa gaaaacttat ggaagaaaaa
      121 aatatagacg cctatatgat tccatcttct gataatcacc aaagtgaata tgtaggagat
      181 tacttcaagt caagagaatt tatatcaggg tttaatggtt cagcggggac agttattgtg
      241 actaaagacg aagctggatt atggacagat ggaagatatt ttatacaggc agagtctcaa
      301 ttagaaggaa gtacaataaa attattcaaa atggggcaag aaggttgccc aactacagat
      361 gaatatttat acaaaaatat tcctgaagga ggaactttag gatttgatgg tagagttata
      421 tctgctagag aaggagctac attagctgaa aagttatcta aaaaaggtat aaagatagaa
      481 tatcaatatg atttaataga tggtatatgg acagatagac ctgctttatc agatagtaaa
      541 gcatttttat tggatgttaa atactgtgga gaaagtttta gctcaaaatt agctagacta
      601 agagaaaaaa tgagtgagaa aggtacttct actcatgtaa taactactct tgatgatata
      661 gcatggttat tcaatataag aggtggagat gttaaatata atccagttgt gctttcttat
      721 gcggtgataa ccttaaaaga agtttatcta tttgttgatg aaagtaagtt aaatgaagaa
      781 atattaaatg aactagctaa agaaaatgtt caaataaagc catatagtga tgtatatgaa
      841 tttgtaaaaa atatagacaa agctgaaaaa gttttagtag atggaactaa gcttagttat
      901 acaatttaca ataatatacc ttgtgaagtt gagaaagttg atgagtttaa tccagtaatg
      961 ttttttaaag ctcaaaaaaa tgagatagaa ttagaaaata taagaaattc acatataaaa
     1021 gatggtgtag ctttcactaa atttatgtac tggttaaagc aaaatgtagg aaagatggaa
     1081 atcactgaaa taagtgctac tcaaaaacta gaggacttaa gaagagagca agaaggtttc
     1141 tttgagccaa gtttcaatac aattgctgca tataaagaac atgctgcaat gatgcattat
     1201 agtgcaactc cagagtcaaa ttataaatta gaggcagaag gattattttt agtagattca
     1261 ggtgggcaat attatgatgg aactactgat ataactagga ctacagtttt aggacctata
     1321 agtgatgaat taaaactaca ctttacttct gtagcaagag gaatgataaa tctttctaaa
     1381 gttaaattct tgcatggttg tagaggatat aacttagata tattatctag aagttgcatg
     1441 tggaatatgg gaattgatta tcaatgtgga actggacatg gtataggatt tgtattaaat
     1501 gttcacgaag ctccaaatgg atttagatgg agagtagtac ctgaaagatt tgatagtgca
     1561 gttcttgaag aaggaatggt aactactaac gaaccaggta tatatataga aggttcccat
     1621 ggtataagaa cagagaatga aatcgtagtt agaaaagctg aaaaaaattt ctatggtcaa
     1681 tttatggaat ttgaggttgt tacattagct cctattgact tagatggtat agtaccagaa
     1741 ttaatgaata aggatgaaaa ggattattta aactggtatc ataagttagt ttatgataaa
     1801 atatcacctt tcttaactga tgaagaaaga gaatggttaa aagtttatac tagagctata
     1861 tagtttgtac tagatacaat aaaaaatcga ggtattataa tacctcgatt ttttattgta
     1921 tcttttatta attttgaaaa atttttaact tgataattct actaactttt tattcattat
     1981 aagtagtata attccaaata tcaataaaaa tgatggtatc actatgaata cttgtaacat
     2041 accaagttgg tctataatag cttgagtata accagataat ttatttgctg caaatttacc
     2101 taaaaaccaa acacccatta gtaatgaaat atacttttca ggcgaaagtt tatttaccat
     2161 accatatccg actggagaaa agcaaatttc tcctatactt tggaatgtta aaaacccaac
     2221 tacccaaaat acacttgctt tatgaattga attagagtcc gtacctgttt gcataactgc
     2281 tactatcata aataaaaatg ctatagctaa tagtataaaa cctaagctca tttttttggg
     2341 tacacttaaa tcgccttttt tagtttgaga taattttacc catactagag cagagatagg
     2401 tccaagaata acacaaagga gaccattata tgaatctatc catgaagtag gaatttgaaa
     2461 attgccaaca gtaagattta tatgctcttt tgtatagagt gcaatagaca tagaggcttg
     2521 gttatatgct atccaaaaaa atactgtgaa aaaagctaat accaatatta ctattattct
     2581 ttttttctca atcaaagtta atggtcttga agcgagcatt ttcttatatt ctagtgattt
     2641 tcttatagat tctctctcat tactatggtt attatttaaa gaattataaa actttctgtt
     2701 tccaaataca aagaagaata aacctattag aaccgtaatt gatgaaaata agaatacata
     2761 tctgtatcca tacatactta tagaggctcc acttttcata gcaaaccatt cattagcaac
     2821 taaaccacat attaaaggac caaataaagt acctagatta gtagccatat atgtaataga
     2881 gaaagctcca tcttttcttg ggtcatcatt ggtatataag tttccaacca tggtatgtaa
     2941 gtttccttta taaaaaccta ttcctaatcc agataaaaat atcatgatgt ttatatccat
     3001 cttactattt gctatgtatc ctagaaaata accaattgaa accattagca ttccaagtat
     3061 gatacagttt ttgggaccta gaaatctatc actgacccat ccaccgataa ctggagagaa
     3121 ataagtccat gataaaaaag atgcaagcat tgatgcggat tctgctggtg ttaaccctaa
     3181 accacctttg gagacttgtt cagctaaaaa taataataat accaatttca tgccatagta
     3241 tgcaagtcct acaaaggtaa atattgaaca gcagaaatat aaatctttag gttgtttaag
     3301 tttttcttgc gtttttaaaa ctgacatatg tcgagaacct ccagataaat agtttaacaa
     3361 aattttacca tactatatga gtatatgttt ttttcataga gacgtcaact tatgagataa
     3421 tttaattaag tcgaaatata tgtaaaaata gtatcatttt tgtgtattca ataatatttt
     3481 tttatgataa tatatgttat tattatatta aaatacaaac atatttatgg aaaggatatg
     3541 ccaatttagt agttagattg attgtttggc aggtgggatg agctatgata agaaagaaat
     3601 ctgaattaca agtagaagta aaagaaaatt taaatggtgg tataggaaat gttaagcttg
     3661 aaaacataat acaaaatgaa gagcttaaag gaaaaggaag actatttaaa agggtatctt
     3721 taccagtagg aagttcaatt ggtgtgcatg accacacaac agattttgaa gtatattata
     3781 tactaaaggg aaaaggcaaa gtatttgata atggggaatt tgtagaagta aatgagggtg
     3841 atgtagtgta tacagctgat ggcgaaaagc attctataga aaatatagga gaagaagatc
     3901 ttgagtttgt agcactagtt ttatatatgt aaaatatgga ggaggagtca tgacaggcaa
     3961 gatagaagaa attaaggaca agataaatag attttgcaac tccaatttaa atcaagaata
     4021 caaggatata agctttaaaa ttttgcaaaa ccttttagat aataataaag agataattca
     4081 ttcttctaga gctgatatat ggtcttcagc tatactaaat atagttttag aacaaaatct
     4141 tttatacaat aagaagcatc cactacatat aacaaaaaaa gagttttcaa aacaaatagg
     4201 tgtttcttta aatactataa ataataaatc atctttaata aaggatgttt gtagtattga
     4261 ctttttaaat caagatacta tagctatttc taatgtagaa ttttgggtaa aagagataaa
     4321 ttccaaatca aagtctgtag atttagattt agaaaagaag aaaatactat ataaaagata
     4381 tattaagcta tcacaagatg caaatagtga tattgaatca attagatata tggaggaagc
     4441 tgtaaatata ggtaaaagta tgattactaa agaagataaa gaacttggat tttggaaagg
     4501 tttatctacc agagcctata tgatagcact tgaatccctt gctaggaagt tagaaagtat
     4561 taataatcta aatgaatcca aaaaagtatt ggaatattta atagaaatta atcctagtga
     4621 tgagcaggga ataagatata aattattaaa tgtattaatt agattaaacg atagaacctc
     4681 aataaataaa ttatttgaac tttataaaga agaaaaatct gctacatgga tgtacagtaa
     4741 agctctttat tactttaaaa ataaaagtat gtttttggca aatgattcta ttaaggttgc
     4801 tagaggtaaa aataagtatg ttggattata tttgttagat tggcgaaatg cttttggtag
     4861 agaatttgtt acagaagaag aaaaggcaga agctgtatat tactatgatg aaaacatagt
     4921 gatttggaat gaagttaaag gttctatgga ttggctatta aaaaaaatgt tggaattttc
     4981 ataaaaaaaa ctactcctta cttttatata agtaaaagga gtagttttta atttacacat
     5041 ctagttttaa atcttcaggt tttattagac ctttttttct cataaattct gaaatcaaca
     5101 aagttacaat agcaggaagt ataaaattaa gtaaaagtat accaacccac atagatgtac
     5161 ctccctttcc aacactttgc atagcagtca ctgttccaaa ttgtccaacc aatccacaag
     5221 tacccatacc agagccgata ggaatattct ccattttgaa tattgttgta gataatggtc
     5281 caagtaatat tgaagctaca gtaggtggta tccaaatttt ccaatttttt attatattag
     5341 gtacttgtaa catagatgta ccaagacctt gtgccacaag gccaccaact ccattttctc
     5401 taaagctcat aacagcaaag cctatcattt gacaacaaca acctacagtt gctgccccac
     5461 cagcaagacc acccaaactt aacatcatac aaatagctgc actacttata ggtaatgtaa
     5521 gagctattcc gacaagtgca gagactaaag ctcccattat tataggttgc atagttgtag
     5581 cttgcattat tatatttcca aatgaagtca taaaagcaga aacagctgga ccaataagct
     5641 cagctacaag tactccaatt agtattgtta cagcaggtgt aaccagtata tctatttttg
     5701 tttcttttga aactaatttt ccaatctcta cagcaaaaag tgtagcaaca aatgctccaa
     5761 caggtcctcc taattcatta ccacaagctc caacaagtgc acaagaaaat agtacaagtg
     5821 ggggtgcttg aagtccatat gcaatagcca ctgctatagc tggaccggta acctgtttag
     5881 caagagggct tataacctca gtaaaaagag aaatattgaa attatctcct aatgtattaa
     5941 aaattgttcc aattaaaagg gaagaaaaaa gaccgagtgc catataactt agtgcatcaa
     6001 taagatacct ttgaacagaa atttcaatgt tttttctttt agcaaatgat ttgaaatttc
     6061 tttttttata attgatttcc aatttaaaat cctcctcata taatataagt ataatttctt
     6121 tttaattaat tatataactt ttcagctgac aagacaaatg ttatttcact aaaattagac
     6181 tattgcaata gtaagaaatt aacattaatt ttagttttaa attttaaatt tatggtttat
     6241 aattagtata gggatattct gaaatataat aattttccag tttatcccaa tatttaactt
     6301 aggtagattg cttacaaaac aaatgattat atattaagct aaaaggaagt ggatagatga
     6361 gatttataaa aaataagaaa tacagaaaaa ttgctataat tatatctatt cctatattgc
     6421 ttgttgcgca gtactacctt tttaaatttg gaatacttag accaatggta aagggagtag
     6481 aaattgaaat tgtagatggg gaatatgtta aagatataga taagtatgta gtaaaattaa
     6541 atgaaacagt tactttatcc actggtgaat atattaaggt tccttcgtat gctaaagatc
     6601 caaatatttg gtttaatgta ttggataatt caggaacttt aaaaatagat ggaaataaaa
     6661 tgacagcatt aaaggttggg tattcttctg tgggtatcat gaaaaattca agagtattaa
     6721 aaaaggctac tataaaagta gtagacccag aggtagagtc actagatatg gagattaatg
     6781 gagatttaaa acatgttggt gatagtgcta ctatagaaag cacaatagag gttgattatg
     6841 acaagtttaa aaaatcatat aagccagttt ataagagtag taatgaaaat attttaaaaa
     6901 tcaaaggaaa tagagtaagt gcagttggag ttggaaaggc tacaatatat gctaagtgtg
     6961 gaaataaaga agttgagaga acatttagga ttgaagctag agttgctgaa ataaatatgg
     7021 atgatataaa aatagaagtt gaccaaaatg aaaaattgaa accagatata ataacttctc
     7081 cacctggttt agaaccacca aaaatatatt atgagttagt agattcaaaa ttacctatag
     7141 aaagagcaat aagtttaagt agtaatggaa atattgtagg gcttagagaa ggcaaagata
     7201 gggtaagaat aacttgtgga gataaatcta aaataataac agtaacagta gtcaaagaaa
     7261 ctataacgaa tgactatata caaaatttgg ttggctcaca taaaatagta aataataaag
     7321 ttattattaa acttgaatgg gattatatga aagatgtctt tgattatgat atatatctta
     7381 aagataaatt gtcaggagaa tcatttaaga aaattaaatc tataactata aatgaaagtg
     7441 atttaggtaa gtctaacaaa gtatatgcaa ctatagaagt agatatgaag gggaatcaaa
     7501 acgtagattt tgatatctat gtcataggga aaaaggattc agatacaact aagccaagta
     7561 atgtaataaa tattactaat gggaatggaa attcaaataa tgataataac attaaagaca
     7621 tgaaagtaga aagtatatca gctaatgttg atagagataa taatgttatt agagtcaact
     7681 ggagtagtat atctcataag gattgtactt acagcatata tgtaaaaaat aatactaatg
     7741 gagatggaga atttactcta tatcaaagtg atatacaggg gaatgagcat actataagta
     7801 ttcctgaagg agacttaaat ctagatattt atgttgttgc aaattataat gggaataact
     7861 ctcaaaatag tgatgttata aatgtaagat agatttgtat acaaatgagt attaagttta
     7921 ttgaaaaatt aaattaagaa aaaggatagt gtgatagcaa tcatactatc cttttttgtt
     7981 aaaatataga ggtttcaaat ttttagttaa aaaaattttt ttattaattg atattgtatt
     8041 aaattgaact tagtgctgct tctattgcat gtattattgt tgtatcaaat agtggaatag
     8101 aagtatcatt ttgtttaatt aaaagacctg tttctgtaca acctaatata acaccctctg
     8161 caccttgctt gccaagctta tctataatag ataagaaagc tttctttgaa gattcagata
     8221 caattccaac acaaagttca ttaaatattg tattatttac tattatacgg tcttcttcat
     8281 ctggaattaa aacatcaatt ccattattaa taattatgtt tttataaaaa tcttgttcca
     8341 ttgtatattt agtacctaat aaagctactt tttttatttc tttttccttt gatgtaaatg
     8401 taagtaatac attattatat caaacagaat caaaagacat aattgaacta ggaacagttc
     8461 atcctccata tgagcaaaat acatatatta ttgattttat taaaagtata ctaaatcaac
     8521 cagaaataga taaattttta caatatatgt ctccatctgg tacgtacatg caaaaaaaat
     8581 caattgcaaa atggatagag agaaataata tatacactag tgaagaaaat atcttattat
     8641 ctacaggagg gcaaaatgct atatgtgcaa ccttactagg attatttaaa gcgggtgata
     8701 ggattgctac agattctttg agttttctgg aattaaatca atagctaaaa taataggtat
     8761 tcaattggtt ccaattcctc aagataataa tgaaatgtcg attgaacatc ttgaaagtta
     8821 ttgtaaaaat gaaaatataa aaggcatata tcttatacca gattatcata atccaacgac
     8881 acattctatg tctgatttat cttgtaaaaa gatagcaaaa caataaatat aataatcatt
     8941 gaagatgcca taaacagtat ttttagagat agtacacaaa ctcctatgtt ttctttggcc
     9001 agtgataata ctatatatat tttttgtaca tctaagtttt tatgtgctgg tcttagaata
     9061 gcatttgtag ttgccccaaa acgatatata gaaaacttag aagatgcact atataatatg
     9121 aatctaatgg tttctccatt tacggcagaa atagtacacc gtttactata ttctcctatt
     9181 ttagataaga ttataaaaga gaaaaaagat acaattatag aaggaaataa agttgctgat
     9241 aaagttttgt cagattataa tttgatgaat tggagggaaa gtcatttgaa atatctgcaa
     9301 aaaatctagg tgttcaagtg tattgtgcag aacgattttc agtaggcaac tctacagtac
     9361 caaaagcaat ccgtatttgc ataacagctc caaaagatgt agaagaatta gaaaaagggc
     9421 tcaatataat aaagtcactt cttaatagct aaatttattt tactatgatt taattaaata
     9481 aataaaaagg cggagaaatt tattataata aacctccgct tttattattt aatgaaatac
     9541 tttactttct attaaaaatt taattttaat aatcttgaaa aaataatcgt tttatgataa
     9601 aataattctt aaaaatagaa aaaattaatc atttgttaaa aaaaatgcat aatatgttgt
     9661 aatttattga cgaaagtaga aaaatattca taaatgtgca aaataataga aaaaatgcaa
     9721 aaataagttc aatttcattt gttataaaat ctatatggca aaatcaaatt tgcctatcag
     9781 aatgatataa acacatcaga aaggaggagg ctatcaaaca atataagtag ttaactttga
     9841 tagcaaaaaa ttatgaatga acaaactaga atatccttag agagagctgc tgaactaaaa
     9901 tcaaaaattg atgattatat tcaggctaga aaaacgatta acagaggtct tgaaaaagaa
     9961 gaagagataa ataaacgaaa acagaaaata ttgagtatat taaatggaac tgaagaggat
    10021 tggaacaact acaaatggca attatcaaat agaataacag atgtagatac tttatcaaag
    10081 attataactc taactaaaaa agaaaaagaa catataaaag aggttggtac tcaatttaga
    10141 tgggcaatat ctccatatta tttaagcctt atagacccag aagatatatg tgacccaata
    10201 aaattattgt ctataccaac atatatagag ttagaagatg agcaagaaga tttggaccca
    10261 atgggagaag agtatacaaa tccagcagga tgtataacta gaagataccc agatagatta
    10321 ataataaatg taacaaatga gtgtgctatg tattgtagac actgtcaaag aagaagaaat
    10381 attggacaac aagattctca taagtcaaaa gctattatcc aagaatctat agattatatc
    10441 agagaaaatg aagaaataag agatgtacta gtaactggag gagatgctct tacattaaaa
    10501 gatgattatt tagagtggat tcttagccaa cttaaagaga taccgcatgt tgattatgtt
    10561 agattaggta ctagaactct tgttacaatg ccacaaagaa ttacagatga attttgcaat
    10621 atgctaaaaa aatatcatcc tatatatata aacactcatt ttaatcatcc aatggaaata
    10681 actaaggagt ctaaagaagc ttgtgaaaag ttagcaaatg caggagttcc attaggaaat
    10741 caggcagtat tattaaatgg aataaataat gataaatttg taatgagatg tttaaatcaa
    10801 gaattactaa aaataagagt aaaaccttat tatatattcc aaagtaaaca tgtaaaggga
    10861 acaaaacatt tcaatacatc agtagatgat ggtcttgaaa tcatggagta tttaagagga
    10921 tatacatcag gaatggctat accaacatat atagtaaatg ctccaaaagg aggaggaaaa
    10981 actcctttgc ttccacaata ccttgtatca aaaggaacag attatgttat gcttagaaca
    11041 tgggaaggaa aagttataaa aatggaagat gaacctgctg tagatataaa gaaacttata
    11101 aaagaacaag cacaggatta aaacagtatt taaattctat aaaaagaaac aactttaaaa
    11161 taaaaagaaa atggatgcta aatttatatc aatttgcatc cattttttat tagttattta
    11221 ttattttgtt gttgattaac taattcaaga tatccacttg ggtggaagta atatatctca
    11281 gaagtatttt catttacaaa gtaaccaata tcgccatctg catctggtaa aaatacataa
    11341 ccattaagat ttttagcttt taatgcttca aaatcactag catttccttg atatatgtaa
    11401 tcaacttcat tgttgtattt tactaaaagt tctttagctt gctcttgagt caatttagta
    11461 ttttggctta caggaacatt cttttgagaa tctgcgtaag aagattcatt tactggtgca
    11521 gttaataaca aacaagataa aactaataaa gatataagtg cttttttcat actaaaaccc
    11581 tctttcatgt ttaattatat aagattcatt acttaataat attgtatgtt tcctataatt
    11641 aaatattacc attaaagaga ataatattac agttacacag ctgtaacttt tgattacaaa
    11701 atcgtaatta aattgtattt ttattccatt tgtattttat catgtctacg atttacaaac
    11761 tcacaaaaat atatttttat aacgcccata acaggagcag atagaatcat gcctggtata
    11821 ccaaagaatc ctccgccaac agtaacggct aagattgtaa agaatgggct aagacctagt
    11881 tgtccaccta cgatttttgg ctctataaat gtaacttcta cttgttgaat tattattaag
    11941 taaattaaag aagttaaagc agttgttgga ttggagaata aattaattat tacaactggt
    12001 gccataccta ttactggacc aaaatatgga accatattca tgacacccat aattgtacca
    12061 aataacagtg catattcaga ttttaaaaag taaagaccaa ttccagaaag tactccaact
    12121 ataaaagaat ctaaaatctt acctgtaaaa tatttaccaa tatttaaatt taagctttga
    12181 catagttcta ttataaagtc tccatatttt ttacctaaag aaatataaac tactttcttt
    12241 gtaaatagta agaatttttc tttttctaat aatatataga aacaaattat aaaacctaaa
    12301 agaaattgta ctataaactt tccaaccgag aatgtagtgc taaatattcc gccaagtgaa
    12361 ccaataagta agttactaaa tttaggcatt acactcataa ttttgtcacc atattctttt
    12421 aatgtattag ggtcaactga ttgtaaactc ttgcctaagt caaataaaaa ctgttctgtt
    12481 ttatctatgt atgtaggaat ttgagcaact aaatcagcta aactatttac tatggatgga
    12541 actgtaaata atataaagga aattagtata actatgagta caccataagt aagaagtaat
    12601 gaatatattc tcttaaaatt taatttactt tctaagaatt ttactagtgg gttgaatata
    12661 tatgctaata caaatgctat tataaatggt gttagtagtg acattaataa acttatcact
    12721 ccaaaaaaat atttgtaatt atcaataact ttaatcaaga tatatgaaac aactacagtg
    12781 agtacaatat ttagataaat ttttttatct tgcaaaataa cacaaccttt cttatattta
    12841 ttaaatttag atatacttaa atctaagtta aagttaatat ttatagctta ttatacaata
    12901 aaaagcagta ttaatatagt ctgattaata tgaaattata aatacgttaa aactttatgt
    12961 ttatggctaa aataataaaa attatttata ttatgttcat atataatcta aaataaaaaa
    13021 taatgccttt aattaaacta
//
LOCUS       DAMKOJ010000090        12683 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.098, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000090 DAMKOJ010000000
VERSION     DAMKOJ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12683
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.098"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(179..748)
                     /locus_tag="PC592_002964"
     CDS             complement(179..748)
                     /locus_tag="PC592_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF4056907.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(820..1428)
                     /locus_tag="PC592_002965"
     CDS             complement(820..1428)
                     /locus_tag="PC592_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF4056908.1"
                     /translation="MDSTDKKGLKSPEIMIINGSPRINKNCSFIANEVKAMLEEYGLS
                     CKIFNIYDMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYILNKPSIDRNKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNDTDNVSYMSNQEFKDIIYKNLKRYIDSI"
     gene            complement(1436..3199)
                     /locus_tag="PC592_002966"
     CDS             complement(1436..3199)
                     /locus_tag="PC592_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HDF4056909.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYLTEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDTFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYAIKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDASYE
                     NNTISMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(3242..3709)
                     /locus_tag="PC592_002967"
     CDS             complement(3242..3709)
                     /locus_tag="PC592_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056910.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSIFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            3892..4353
                     /locus_tag="PC592_002968"
     CDS             3892..4353
                     /locus_tag="PC592_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056911.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILDEKIVNETNFKISYRNYIETLINIQNENLSNFKKKSTKTAKCFNISQIT
                     QLKNLLNNTGYNLLIPYKYLTSRDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            complement(4446..4616)
                     /locus_tag="PC592_002969"
     CDS             complement(4446..4616)
                     /locus_tag="PC592_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056912.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(4805..5026)
                     /locus_tag="PC592_002970"
     CDS             complement(4805..5026)
                     /locus_tag="PC592_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF4056913.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(5110..6336)
                     /locus_tag="PC592_002971"
     CDS             complement(5110..6336)
                     /locus_tag="PC592_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF4056914.1"
                     /translation="MKKVVIIGGGPAGMIAASTACERGCDVTLVEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNEDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNNKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIMDTKPSLIGIEVQESFTRDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTIILDLKPALDEEKL
                     DKRIQKDFQKYTNKKFEKALDDLLPKKLIPVIVNLSEINPDTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIDEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            complement(6397..7329)
                     /locus_tag="PC592_002972"
     CDS             complement(6397..7329)
                     /locus_tag="PC592_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDF4056915.1"
                     /translation="MDIQLSILLFFQNLRNPILNFIFLVLTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYIHVIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVIF
                     IKIFDYIDDNKNYILLLVLLIPFIIVAIFLNSSEYFEKFGIIVGFVFGYIVEDRFVKF
                     NTDNNNKKINFSSKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSINFMNFIKNTVVVFYGVAGAPALFKVLKLN"
     gene            complement(7418..7945)
                     /gene="hpt"
                     /locus_tag="PC592_002973"
     CDS             complement(7418..7945)
                     /gene="hpt"
                     /locus_tag="PC592_002973"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF4056916.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            8174..9250
                     /locus_tag="PC592_002974"
     CDS             8174..9250
                     /locus_tag="PC592_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF4056917.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSMDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSMDKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTNTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGVISNTNVKNEINKNIDLWNINIIASKMGEIMFSDLDFISNTISLVSAERNY
                     LLKELKNIKNLNVYDTKGNFILCKIKTKELTAKSLREKLIPQKIIIRDCCSFEGLNEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(9358..10566)
                     /locus_tag="PC592_002975"
     CDS             complement(9358..10566)
                     /locus_tag="PC592_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF4056918.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFVVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGSKEKQSA"
     gene            10965..11147
                     /locus_tag="PC592_002976"
     CDS             10965..11147
                     /locus_tag="PC592_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056919.1"
                     /translation="MINIKPKENKHMTKTMICDYCNKVINNNSEYITFHKKNYVKTSV
                     CINCVLKLMDKTKENK"
     gene            complement(11469..11657)
                     /locus_tag="PC592_002977"
     CDS             complement(11469..11657)
                     /locus_tag="PC592_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4056920.1"
                     /translation="MIKMRLKGKVTVLILACLVSIGVVGCGDKENNDTTKNKAEKSIT
                     DGQENSTDTAPDVTSDSK"
     gene            12060..12377
                     /locus_tag="PC592_002978"
     CDS             12060..12377
                     /locus_tag="PC592_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056921.1"
                     /translation="MNFGNINLIIIGVGIIILTTIISLIKPKISFCSEKYFNKLESIY
                     GNIDRKRTVKLEVLSRYVMGLEYIVIGLFTRRLDITIIAMIIVAVITTVLYYLIRKKY
                     ITI"
     gene            complement(12438..>12683)
                     /locus_tag="PC592_002979"
     CDS             complement(12438..>12683)
                     /locus_tag="PC592_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4056922.1"
                     /translation="NNSVLDNLYVAKNGENKEDDLVDALSVGVLAGKTESPVIIVGDG
                     IKDVQKSLIKKKEFRYITQIGGNGNEKAFSEIENLVK"
BASE COUNT         4343 a         2047 c         1313 g         4980 t
ORIGIN      
        1 tatatatata attttaccat attacatcat atttttgtaa gtttttatta cattttttat
       61 aatacccctt tattttataa attaatctaa tcgattaaat ttatcctata gaaatttatt
      121 acatttaaaa atatgctagc aaataaaata tctactagca taaagtctat ttataatatt
      181 aatcaactat taattctact aagtctccat ttttaacgcc tgctgcattt ccctcttcca
      241 tatcaacatg catttctaga ttaaagctat cactagctct tactaataca ttttcaaata
      301 ctaatgctct tggtccagat gttttaactt ttactatttg tttatcagtt acaccaaatt
      361 tagcagcatc ttcattgctc atatgtatat gtctagaagc aactataact ccttctttca
      421 tttcaacttc tccagcagga cctactagtt taacacctgg agttccagct atatcaccag
      481 attcttttat tggtgctttc actcctaatg ggaaaccatc tgctaaagat atttcaactt
      541 gagtatgagc tctagctggt cctagtactc taactccttt taaagttcct tttggtccta
      601 ctaaatccac tttttcttca caggcatatt gccctggctg agataatggt ttaaatttag
      661 ttaactcatg acctgcacca aataatacgt ctatatcagc ttgactcaaa tgaacatgtt
      721 tattggataa tgctattggt aatttcattg aaatttcctc cttttaatta tttaaattat
      781 tgcaatacaa ttatacataa tattacctac aaaatcaaat tatattgaat caatatatct
      841 ctttaaattt ttatatatta tatctttaaa ttcttgattg ctcatataag atacattgtc
      901 tgtatcgttt aaatatatat tgtgtaaaag tttagtattt atactcttaa agaaaaaatc
      961 cataacaatc tgtccacctt taaactgtga atcatatgat ttactacccc ctactgcaat
     1021 atacattcct atccgtttct tgtttctatc aattgagggc ttatttaata tatatttact
     1081 tgcatatata gcttgtgttc tatcaacaac tgtctttaat ttagctgata ttgaatcaaa
     1141 atgtacagga cttattacta tagttccttt tgaatcatca aacattttat ataatggctt
     1201 catatcatca ttaaacttac aataccctgt tttttcacaa aatccacatg ctgtacaata
     1261 ttcaatatcc atatcgtata tattaaatat tttacagctt agtccatact cttctagcat
     1321 agcttttact tcatttgcta taaaactgca atttttatta attcttgggc ttccatttat
     1381 tatcataatc tctggacttt taagtccttt tttatcagtt gaatccataa tcaatctacc
     1441 tatcctttaa cataactatt aaaatatcat catcataatt atcttttgat gagaaattct
     1501 ttaaatccaa ctttagattc tctactatta actgttgatt taatctaaag ttttctttta
     1561 gaaagttttc taatctgttt ataccatact cttcttttga tgaatttttt atctctaaaa
     1621 ttccatcagt atacatacat accattgcat aatcttccat tgaaatagta ttattttcat
     1681 aactagcatc ttccattatt ccaataggta tacccttttt acaatttaaa ttattttcta
     1741 ttgtaccatc cttctttacg actacaggac tatagtgacc tgcattagac actgtaatca
     1801 tgttttcttt agtatctata atacctatca aacaagttgt aaatactccc atcttgtcaa
     1861 attcatcata taacatccta tttagatttg tcattatttc tcttggtgta ttgtattgat
     1921 tacataatac cttaaaagca ccttttatca ttgcaacaac ataatttgat accattccat
     1981 gtcccattac atcagcaaca atataaacta tatgttcgtc atctactttt atagcataat
     2041 aaaaatctcc acctactact cttgctggtt tatgataaaa ataaagttct ttctcatcat
     2101 tacaatccat tttaccttta tccataataa gctgttgctg tttatttaat atgttcagct
     2161 cattttcaag aactttgtgt tttacttcct tttcattatg ttcatataat tgcataccaa
     2221 cagaaacttg tttggacagt atactaagaa tattcaaatc atcactagta tagtttttac
     2281 tatttgcaca aactatacat cctatagtct catttttatc ctggagtttg taatatatat
     2341 aactttccaa atttattcct ttttttgagc atggttttaa attatttaga taccctccca
     2401 atgattcttt ctttaaaaac gtatcaatca taggatataa atttgttttc tttttttgct
     2461 caacattata acagctaact atagcatcct tattatgatg actatttata attattaaag
     2521 cttctttact attagtaata ttgcatgctt gtttacttaa attttctaaa aagccatcaa
     2581 tactcttatt aaggtatagt tttttagtag cttcatttat ggcacttatt gagcctctta
     2641 gtttatcaat taaaatttgt acattattat ttttattagt tatttctatt gataaactta
     2701 agagtgatgc aacagatgat ataaagtcta tatcttgttc tgttaaataa tcatcctctt
     2761 ttaaaaaaca agtcataaat ccaacaacta cattatttat tataaaagga aaaactattc
     2821 tcccaatata accttcagct tttgctaaat ctcgttcacc ttctgctctg gaatcttcaa
     2881 atacattttc cacatatatt atcttttttt catttacagc ctcatgtata tactctggat
     2941 acgtgtcaaa atcaattttt gcacctttaa gactatttat tggaaaaatt tgaggtacat
     3001 attctaaggt ttgtgaacat actaagtagg catatttaga atcattttta taaaatagat
     3061 tcacacatgc ctttgtaggg tgaacaactt ctaacatttt ttctattatg tcatctttta
     3121 tattaaaaaa atctgtagat tcagttacca tagcggatat ctccactaaa ttcttcattt
     3181 tataactgcc attagtcata ctcaatttct ccccctatat attaaactat ttattagtat
     3241 tttaacatac attctttata gtaaaaacaa aaacaacgac aaaactagca actaatatcc
     3301 agttaaatcc tgttaataat cctataagaa gtaatgtaat taatgcattt agacctgttc
     3361 tacctttttc atccataaaa gttattttag agatgtcgat attatttttc acattattta
     3421 tatgttcttt tacttgttct tccatatttc ttttatatag tatataaact acaccaacta
     3481 aaaatactcc tatacctaga accatgttta aattaaaagc taccataagc aatattgaac
     3541 caaaagccaa ctttaaaagc ttaaaaaata tactatctat ctttaaggtt atatttctga
     3601 tttctttaca ttcgtctctt aaagaatatc cacttgaatc taagttatta atctttgttt
     3661 ttacaatttc agaataaaaa agttttatta ttccatttaa cattttcatc actcctaaat
     3721 attttacata tatttgtaag ttttacaatt ataatatttt ttatacttgg taataataaa
     3781 aaataacaaa tattttatga tttagtattt attgtaaata aattattgaa gctttattag
     3841 ttaagtatag atttttaata actattttta taattagaag gaagtggttt tgtgcaaata
     3901 gaacaacttg atttagaaac gagaaataaa atatactgct atacaaaaaa aattcttaga
     3961 aagtatcaaa aaggtataac atctggaaaa ttaacagccg ataaatttgc agataatata
     4021 ttgtctcaag attttatcag tagtatactt gatgaaaaaa tagtcaatga gaccaacttt
     4081 aagatatctt atagaaacta tatagaaact ttgataaata ttcaaaatga aaatttatct
     4141 aactttaaaa aaaaatctac taaaactgca aagtgcttca atatctctca aataacccaa
     4201 ttaaaaaact tactaaacaa tactggttat aatttattaa ttccatataa atacttaact
     4261 tctcgtgata tagaaggaat cgttactctt attaatactg ggtctattga acttggaaat
     4321 gagagaatct ataattatat atccaaagca taataattta aacctattat aaaaaggcaa
     4381 tttatttaat aaaaaatatt tttaatatta aataaattgc ctttttaatt ttggactaaa
     4441 tactgctatc caagtgcttt ttctagttta gataaatgtt gtattggata atattttagt
     4501 agctctttaa actgttctac tgatagacct tctgttgttg tatatattct tattttttca
     4561 tctaagtcac tattaataaa tttgtttttt aaatcctcaa aatttacact actcatttta
     4621 catcactcct tatgtaacat attcatttgt attattttat ccaaatacat aaaatttatt
     4681 acataaaaat atatctattt aataatttaa taaaaaaaag ctatctcaat ttagaaatta
     4741 ctttctatat ttgagatagc tttagctaaa ctaatagcca atagttataa ataattattt
     4801 ataactatct gttgcttttt ccagccattt gttgttcagc catttcaact aattttttag
     4861 tcatgtatcc acctacataa ccattttctc ttgcagtaag gtttccttta tcaacttgtt
     4921 gataattact cataccaagt tcattagcta tttctaattt catttggttt aaagcctctt
     4981 ttgctcctgg tactactgtt ctgttgttgt tattgttact tgccatgttg attaccttcc
     5041 ttctgtttaa tttattttgt gttgctgata atattatgtg attttaaaca tttttaattc
     5101 aggtaatttt tagcaattaa aacctgctaa atatccagta gaaaaagcta tttgcaaatt
     5161 gaatccacct gtatatgcat ctatatctat tacttctcca gcaaaaaata aaccttctac
     5221 taattttgat tccattgtac ttgaatttat ttcatttact tttacaccac cagaagttat
     5281 tatagcttca tcaataggtc tgtatctctt tactgtaaac tttaaatttt ttaataaatg
     5341 gactaagttt tttctctgct ctctagaaat ttggtgaaca actgtatctg gattaatttc
     5401 actcaaattt actattacag gtattagttt tttaggaagt aaatcatcta atgctttttc
     5461 aaatttttta tttgtatact tctgaaaatc tttttgaatt cttttatcca gtttttcctc
     5521 atctaatgca ggttttaaat ctaatattat agtgtaattt tctttccttg tatctttcat
     5581 tctacaactt gcagacttga ttataggtcc atctaaacca aatttagtaa attcaagttc
     5641 tccaaaatca ctataaactt tcttttgttt gctattaaat actcttattt caacatttct
     5701 caatgataat ttttctaaat ctcttgtaaa actttcttgt acttctatac caattaaaga
     5761 tggttttgta tccataattg tatgtccttg tgaaattgca aatttatatc catcaccagt
     5821 agaaccagta agtggataac ttaatccacc agttgctact acaactgaat cacatttaat
     5881 ttctttctta ttgtttaaaa ttactttttc aattttatta ttcttagata ttattttttc
     5941 tactttcgaa tttaataata tatttacttt cttactttta agttgtcttt caagagcgtt
     6001 tacaatatca aatgctttat cgctctctgg aaaaaccctt tttcctcttt ctgttttagt
     6061 ttttactcca agattattaa acatacttat tacatcttca tttgtaaaag tataaaaagc
     6121 actataaaga aattttccat ttgtaggtac attttctatt agttcttcta tttcacaggc
     6181 gttggtaata ttacatctac cttttcctgt tattgcaagt ttttttccta atttatgatt
     6241 tttctcaact aacgttacat cacagcctct ctcacatgca gttgatgcgg ctatcattcc
     6301 tgctgggcca ccacctatta ttactacctt cttcaaataa tcactctttt ctacccttaa
     6361 tttttttaat ttaaactatt gattatatac ctcaaatcaa tttaatttta aaactttaaa
     6421 taatgctgga gctcctgcta ctccataaaa aacaactact gtattcttaa taaaattcat
     6481 aaaatttata ctcatagtag agtcacttat atttaaagta actattaaca ttgaaataaa
     6541 caacttaatg ccaatatata acattcctat tgttactatc ccaaccaaaa acctacatat
     6601 tcttgaaaaa attatatttt tactcccctt atttttactg ctaaaattta tttttttgtt
     6661 attattatct gtattaaatt taacaaatct atcctcaact atatatccaa atacaaaccc
     6721 tactataata ccaaattttt caaaatattc agagctattt agaaatatag ctactattat
     6781 aaacggtata agtaaaacta aaagtaaaat ataatttttg ttatcatcaa tatagtcaaa
     6841 tatttttata aatattactg taaaaaatat acctaatatc caaccagcta tcacatctat
     6901 tggccagtga acagctaaat acaacctaga caaccctact cctaaaacca tcactgcacc
     6961 tattacatgg atatatctct ttttaaatat agtcataata ctaacccaaa acgtggttgc
     7021 agtttgagta tgagcacttg gaaaagaata accgccagca gtagaaactc tcaatgactc
     7081 aagacctttt attcctattg gtctaggagc ttttacaaac tcttttatgc ctaaatttac
     7141 aacaaaattt ccaattatag caaacagtat tttctgtcca cattttttat ttatacacca
     7201 gtatataatt gttgtaatta atattaataa cggtgcttct gtgcttatcg taagtacaag
     7261 aaatataaag ttcaaaattg gatttcttaa attttggaaa aataataata tacttaattg
     7321 aatatccata tagatgtctc ctttactaaa attttatata attaactaaa aagcactaac
     7381 tcccttagaa attagtgctt ttgattcaca tttaaatcta ttctacgtcc tcaactatac
     7441 ctatgtaagg taaatttcta tacttttcag cataatctat tccataacca acaataaatt
     7501 tgtcttctat aacaaatcca acataatcta caggtatatt agcttttctt ctttgaggtt
     7561 tgtcaagtag agtacacagt tttaaagatt ttggatttct agtttttaaa gctgccacta
     7621 gattacttaa tgttaaacca gaatctatta tatcctctac aatcaacaca ttctttcctt
     7681 caatatctac atctaaatct tttaatattt taactgttcc agaagactct gttgaattgc
     7741 cataacttgt aacactcata aaatctatat ttacatccaa atctatacat cttattaaat
     7801 ctgatacaaa tacactagct cctttaagta tacctaccac tagtaaatct tcgcctttga
     7861 agtcttcttc tatcttcttt cctagttcat aaactttctc ttttatttgt tcttctgtca
     7921 acatttttcc tgtaactttg tacattttgt atcctcccgc tttccttcta ttaacttata
     7981 tattatagca taccaaaata tcaattaaaa tctttttcag catttttaaa cctaaattaa
     8041 cagtttatcc atactttttt gcttttttca ttaaaaattt ggaataacga ttcctttgta
     8101 ttataatcta tatgtacata tattaatcag ttatttttct cgattatata attttatttt
     8161 tggaggtact tttatgagca caaatcatgg agctaattta tatagtttat ctagtaagta
     8221 tggcttttca aaagaagaat ttatggactt tagctcaaat ataaatcctt ttggtacatc
     8281 aagtttagcc aaacaataca ttgtaaacaa tatagatatg gtatctatgt atcctgaccc
     8341 tgattacata gacttaaaaa cttctatatc caattattgc aaatgttcta tggataatat
     8401 agtacttggc agtggagcta cagaactaat ttcatcattt atacatacaa ttaatcctaa
     8461 acaagctctc ttactctccc cagcttattc agagtatgaa aaagagttat ctaaaattaa
     8521 ttgttctatg gacaaatact tcgccaaaga agaagataat tttcatataa atttagaaaa
     8581 tcttataaaa actatcaatg ctaaagatta tgatttggta gtgatttgta atcctagtaa
     8641 tccaactgga tttgcattta ctaaagtaga agtgagagaa attttaaaaa atacagactc
     8701 atttttaatg attgatgaga cttatgtaga gtttactgat acaaatacat actcttgcac
     8761 tcaattagtt gatgattatt ctaatttatt cgttataaga ggtacatcaa aatttttttc
     8821 aacgcctggc ataaggcttg gatatggtgt tatatctaac actaatgtta aaaatgaaat
     8881 aaataaaaat atagatttat ggaatataaa cataatagct tctaaaatgg gagaaatcat
     8941 gtttagtgat ttagatttta tatcaaatac tatttcttta gtaagtgctg aaagaaacta
     9001 tttacttaaa gagcttaaaa atataaaaaa tttaaatgtg tatgatacta aaggtaattt
     9061 catattgtgt aaaataaaga caaaggaatt gactgctaaa tctcttcgtg agaaactaat
     9121 tcctcaaaaa ataataataa gagattgttg ttcatttgaa ggtctaaatg aatatttctt
     9181 tagggtatgt atattaaaac ctaatgaaaa taaattatta atatcatctc ttaaagcaat
     9241 ttttaaataa aaaattactt tatcttataa tttgtacaat catactttta tcatttcaac
     9301 aatgtaaaag aggcttatct ctattttgag atagcctcat ttttatctat ttacaaacta
     9361 agcactttgc ttttctttgc ttcctttttt actcattcca tcatttattt tatctactac
     9421 tactgctatt gcattatctc ctgatacatt acatgctgta ccaaaactat cttgtgttaa
     9481 gtataaagct atcattaaac ttgcaagtcc accatctgat ggtattccaa ccattggtag
     9541 aaaaggaaga gcactcatta tagctccacc tggcgctcct ggtgctgcaa ccattgctat
     9601 acctaacatt gcaatataag ggaataatac acctattcca tgtggcatac cgttcatcat
     9661 taaaactgct gttgtaaatc ctgttattga tatcatacta cctgataaat gtattgttgc
     9721 acaaagaggt acaacaaatt ctcttatttg cttacttact ccattttttt ctgcacaacc
     9781 aacattaact ggtatagttg ctgctgaaga ttgagtccct atagctgtta aatatccagg
     9841 tacttgattt tttaacattc ttactggatt ttttcctgaa aatacgcctg ctgctgtgaa
     9901 ttgacatgcc atatatacaa aatgtaaagg gattactact aaatagactt tccaaaatac
     9961 tcctaatatt gtccatactt ctcctgctat agttatattt gcaaaagttc ctgctatgta
    10021 taaaggtaat aaaggtataa ttactgttga caacgttttc gttacaattc cttgaaattc
    10081 ttggaagaaa ttaaataaag tctctccttt tccgtgattt cttaaagctg atattccaag
    10141 tcccattaca aatgcaaata cgattgcagc tgttacatct accataggct ctaatggaat
    10201 tgtaaatatt ggagctaaca ttcctgcctc tgggtctcca atttgacttg caacactcgc
    10261 atcaataaaa tttgggaaga ttaatgtaga tactacaaat gataataatc ctgctattaa
    10321 agtagaacca tatgctattc ccgtagttat ccccaataac tttccggctc ctgttgctaa
    10381 atcagctata cctgctgtta caaaacctat aattataaat ggtataacaa attttaggaa
    10441 tgctgagaat aaagtactaa ctgttactaa tatttgtacg attatttctg gtgcataact
    10501 tccgattaaa ataccgacta tgataccgat gattagtttg ggcactaaac ctattttttt
    10561 cttcataata tttaccctcc ataacttttt taaattaagc attcttgtac attgaatact
    10621 tagttaaata ttggatatcc acttattatg ataatagagt tttacctctc cgtcaacaat
    10681 ttaaccattt tttgttaata aaaaaaagaa taacatatat aaagtgttcc ttttatttat
    10741 tttattttat atatatgtct attttcaata ttttataatg ttgatactct ttattttttt
    10801 aactttcgtc agttgaatgt cagtaaaata ttttatccac atatttcata tagttttccc
    10861 acaacttatc cccgatatta tttataaaca aaaagataga tactagtaac tctgttttaa
    10921 ctagtatcta ttaaggtata caccaaatat attagaactt aattatgata aatataaaac
    10981 caaaggagaa taaacatatg actaaaacta tgatatgtga ttattgcaat aaagtaataa
    11041 ataataatag tgaatacatt acttttcata agaaaaacta tgtaaaaact agtgtatgta
    11101 ttaattgtgt gttaaaatta atggacaaaa ctaaagaaaa taagtaataa acaatattat
    11161 ttgagaaagt gaagaaaaca ctctaccata aggaaaatgc tctatctaat ataaatatgg
    11221 taaaaaagta aagatgtatt gggcgtacat ctttactttt ttaccatatc acattactac
    11281 cctaataaaa acagctttat gtacaaaaac accatttaaa aaggatgttt tcttggataa
    11341 tattgtttta actagtaaag atatattgag gggttatctt tacctttttt attatattat
    11401 aaatttccta aaagtaaaat tataattaaa atatgtataa attacaataa ttagtaaact
    11461 atcttttatt atttagaatc acttgttaca tctggtgctg tatcagttga attttcctgt
    11521 ccatcagtaa tacttttttc tgctttattt ttagttgtat cattgttttc tttatcacca
    11581 caacctacaa ccccaataga tactaaacaa gcaagtatta ggacagtaac tttccctttt
    11641 aatctcatct ttatcatcct cctagataaa tattaattca ctatttaaaa ttatagcaaa
    11701 gtaatgttaa tcttatgttt attgtaaaaa atatgtaatt tatatgctta gaatattata
    11761 ttttctaaca aaatgtaata tagtagaaaa tacattaatg aatttcaaaa aataagcact
    11821 catataaaga gtactttagt gtatattaat gaatgtttat aatctaattt aacatgtctt
    11881 atgttttagt atgataattt tcgttcgctt tattattaca acttatgttc tagttttatg
    11941 tatcctgcta atatttgtaa tattttagat acgctttatg cttatgttgc tgatatactt
    12001 tgattaagaa aaaaaatcta atataaactg gtgattatat tataaaggag gtatctacta
    12061 tgaattttgg aaatattaat cttataatta ttggagtagg aattataata ttaactacaa
    12121 taatatcttt aattaaacct aaaattagct tttgtagtga aaaatatttt aataaattag
    12181 aatcaatata tggaaatata gatagaaaaa gaactgttaa actggaagtg ctttctcgat
    12241 atgtaatggg tcttgaatat atagtaatag gtttattcac aagaagatta gatattacaa
    12301 taatagcaat gataatagta gccgttataa caacagtatt atattatcta attagaaaga
    12361 aatatataac tatataaaat ctaataaaat taatactaga agaaggtagc aactagttac
    12421 ggttgctacc ttctaatcta ttttactaaa ttttctattt cactaaatgc tttttcattt
    12481 ccatttccac caatttgagt tatatatcta aattctttct tctttattaa acttttctga
    12541 acatctttta ttccatctcc aactattatt actggtgact ctgtcttacc tgcaagaaca
    12601 cctactgata atgcatctac taaatcatct tccttatttt ctccattttt cgcaacatat
    12661 aaattatcta aaacgctatt att
//
LOCUS       DAMKOJ010000091        12652 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000091 DAMKOJ010000000
VERSION     DAMKOJ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12652
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.099"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(265..789)
                     /locus_tag="PC592_002980"
     CDS             complement(265..789)
                     /locus_tag="PC592_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF4056923.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVKTDAADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(854..1606)
                     /locus_tag="PC592_002981"
     CDS             complement(854..1606)
                     /locus_tag="PC592_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF4056924.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPENIKKIYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1637..2935)
                     /locus_tag="PC592_002982"
     CDS             complement(1637..2935)
                     /locus_tag="PC592_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF4056925.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHTVESTKEILDKNRFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGLLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISIGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2952..5216)
                     /locus_tag="PC592_002983"
     CDS             complement(2952..5216)
                     /locus_tag="PC592_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF4056926.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5470..6288)
                     /locus_tag="PC592_002984"
     CDS             complement(5470..6288)
                     /locus_tag="PC592_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF4056927.1"
                     /translation="MFKINNLTYQYEKNANALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEIFFKEEKLKYDKKSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGIDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHKNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6281..6979)
                     /gene="cbiQ"
                     /locus_tag="PC592_002985"
     CDS             complement(6281..6979)
                     /gene="cbiQ"
                     /locus_tag="PC592_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF4056928.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLHSFEIFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6982..7266)
                     /locus_tag="PC592_002986"
     CDS             complement(6982..7266)
                     /locus_tag="PC592_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF4056929.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7256..8008)
                     /locus_tag="PC592_002987"
     CDS             complement(7256..8008)
                     /locus_tag="PC592_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF4056930.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAMPVFLAAALGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8195..8387)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8519..10291)
                     /locus_tag="PC592_002988"
     CDS             complement(8519..10291)
                     /locus_tag="PC592_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF4056931.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKAIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYAFVLYSMDKHPALDSMTRRIVNDIRNIDTK
                     QDIMEVLKELDVIYLTYFEYILNEEESSLIDENNVKNVEVDFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKSSNLADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRSVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKTRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSLKNSENIFEYFCAGNNRDGLAIKSICSGLINRYEENKILIVLSDGRPNDIKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10305..11234)
                     /locus_tag="PC592_002989"
     CDS             complement(10305..11234)
                     /locus_tag="PC592_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF4056932.1"
                     /translation="MNIIDNLRAQGVDEKLIEDVMYFRNYYGLEKDLEYRVTRSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIQFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            complement(11640..12248)
                     /locus_tag="PC592_002990"
     CDS             complement(11640..12248)
                     /locus_tag="PC592_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF4056933.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVVSSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(12425..12541)
                     /gene="rrf"
                     /locus_tag="PC592_002991"
     rRNA            complement(12425..12541)
                     /gene="rrf"
                     /locus_tag="PC592_002991"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         4015 a         2283 c         1316 g         5038 t
ORIGIN      
        1 aataagtgtt ttccacatat cttattatat ttatttaata cattattatt taaaaataaa
       61 gatataagca atcatagtaa aattttttta atagaggttt attttttagt taaaatccta
      121 caatatatag ttttctctaa tacaaaaaaa ttaaaaagtg aaatgtattt gtctaaaaac
      181 ataacaacat ttcactttat tctcattatt aagtaatata tttttaattt ttatttataa
      241 ctcaatctag tttttatata agttttagtt tttttctaca tctgaataat ctattccaaa
      301 agtttctaca gtaacagatt tcataatttg tggagtttgt ggcttatcag ctgcatctgt
      361 tttaactgat gctatttcat caactgtatc cataccttct atcactctac caaaacctgc
      421 atattgacca tctaagtgtg gtgagttttt atgcattatg aaaaattgag aaccagctga
      481 attaggtgcc atagttctag ccattgatat gactcctctt tcatgtttta aattgttagt
      541 aaatccatta ccactaaatt ccccttttat tgagtgacct ggaccgccca ttcctgtacc
      601 atttgggcac cctccttgta tcataaatcc tggtattact ctatgaaata ttattccatt
      661 gtaatatcct tcatttacta atgatacaaa gtttttaact gtatttggag ctatatttgg
      721 atataactca attttaattt cttttccatt ttccatttct atagttacta taggattttt
      781 attttccata atttattacc ttccttttca ttagttaaat tacataatta catttattat
      841 attatactct aaattaaagt ctatcaagta tattttttcc tatttcgtat ccttcctgat
      901 aaatagtttt acaaaactca tcatcaaagt taagtgtatc tttaggagca aattgagtgt
      961 taggtctaac tactattatt ttatcttcat cgtatatttt tttaatattc tctggcaact
     1021 cataattata ttttgtggat attaaaataa ttttatccac attatcccca attaatggtt
     1081 caattaatgc actcctaatt aaacctccat ctaatttgaa accatcataa attccttctt
     1141 gcacatcttt cacaaattgt tctttaaatc caagagttgc atttggattt gatggcaata
     1201 acccactgta tgaaatactg ataattgctt cattacgagg catttttgat acatcaacaa
     1261 tcttttctga tactacctta ttatcaactt caacataatt aacataaaag ttcatttctt
     1321 ctatattact atcatctagt tcccttaggt tgtctatagc aggagaatta tccacagtat
     1381 tatttactat tttcacattc ccattctgga tatcttttat atttgtccac attttctcca
     1441 agttatcaac attccctgtg tacaaataat atccatttat tgctcctatt gatgtccctg
     1501 aaatagaata aaatttattt attcctccat catacaaggc tttaactact cctgcttgat
     1561 aagccccttt tgctcctcca ccttctaagc ataatcctaa tttcatagtc tcatctccaa
     1621 attgtttttc ttatatttat atttcaaaaa acttactaaa tgttttatat atactatagt
     1681 ggtcctcgac atttcctaat tctcttatag agtgcattgc taaaattgga cttcccacat
     1741 ccacagatgg tatatctata tgagtagaag atattggacc tatagtactt ccacctcttt
     1801 catctgacct attaacaaat tcttgatatt caacattagc ttctctacat atatttttat
     1861 aaatagctat agaatatcca tcactagtat atgcctgact agcatttatc tttataactg
     1921 gaccttttcc cataattggt ttattagttg ggtcatgctt ttctggaatg tttggatgga
     1981 tagcatgagc taaatctgat gatatcataa aagatgaata aatagattca aagaatcctt
     2041 ctctatcctt acctattgat atgcaaatcc tctccaatat atttaacaac atgtttgaat
     2101 ctgcaccttg tttagtagag ctaccaactt cttcattatc aaatacagcc attacattta
     2161 caccatgttg acctttagta ttaacaagag catttaagct agcatgtacc attgcaagat
     2221 tatcttgtct cccaatagat ataaattcat cattagcacc tattaaactt cctttttcaa
     2281 attcatataa aaataaatca aaatctataa tatcttccat atttacatct aagttagatg
     2341 ctatttgctt tataagaaaa ttatcttttt ctaatgtatc atttaacagc ccaactaaag
     2401 gtaacatatc tttttgctta ttatatgaat gaccatcatt tatgcttcta tttaaatgta
     2461 tcgctagatt tggtattata caaattggct ttttaaagtc tataagcctt tcatttggtt
     2521 ttaatatact atcacctttt aaaactactc taccagctat cccaagaggt ctatccaacc
     2581 atgtacttaa tattgctcct ccatagcatt ctgtatttaa cttcaaataa gatttttcag
     2641 cttctatttc tgcatttggt ttaatactaa atgtaggaga atctgagtga gagcctatta
     2701 ttctaaatcc atctctttct atatcttctg aatttactac aaaagctact atagctgata
     2761 aattcttagt aacataatac tttccaccaa cccttagatt ccatctctga ttcaaaacta
     2821 attcttcaaa tctattttta tctaagattt ccttagtact ctcgactgta tgaaaagacg
     2881 acggactatc atatatgaag tctattaagt ttttagcaaa gtttatacta tccattcctc
     2941 atttacctcc attataaaat atttagtgtt gtatattctt tatttatttt tttaattccc
     3001 tgttggtcaa aagctatagt aacatctgtc ccaattatag aaactactgt cccaacccca
     3061 aatttaggat gatgtacttt agaaccaagt tttatatcat ctggattagt ttctttatta
     3121 gaatctttta ttgtagcatt aactttatct gcaactttag atttacttat agtactcata
     3181 tactttttag tatatttatc taacatatta taacttgctt tagaatagct tagttctttt
     3241 tttactttgt acaatctttc tatacattct tctggcagtt cttccataaa tctggaagct
     3301 attgcaacat ttgttttacc atataatgtt ctcttctccg tcaatgacat atatagctct
     3361 tctttagctc tagttatacc aacataacaa agtcttctct cttcttctat ttgtgaatca
     3421 ctcatagatt ttatagctct tgatatagga aataatcctt cttccatacc tgttaaaaac
     3481 acaacaggga actctaaacc tttggatgta tgaattgtca taagcgaaac cctatcattg
     3541 tcttcctcat catttgattc agatgtaagt gctatacttg ttaggaatgt ctctaagtct
     3601 ttattttcat aagtatcatc attactactt tcaaactcca aagctataga tataaattct
     3661 ctcaaattat caattctgtc ttgagcttct tcacctttac ctgttaaatc tttttcattt
     3721 ttatttctta tctctacaag ctcgtccata tatcctgtag tgtccaaaac tttttctata
     3781 agtttactaa caggataaac ttcttttata gttctaagag tccctataat atcaacaaat
     3841 ccacttatac ttgctcttgc cttggtagat atatctgaat ttgtttctat atcaattagt
     3901 actgagtata tgctctcttg ttttaaatta gctctatctt caattttttc tatagttcta
     3961 agccctatac ctcttctagg aacatttata atccttttta tagatatatc atcttgtgga
     4021 ttttgaataa ctcttaaata cgccaacaaa tcctttattt cttttctctc atagaatttt
     4081 gtaccaccat atatattgta tggaatttga cttctattta aagcgtcctc tacaggtctt
     4141 gcctgtgcat ttgctctata aagtactgca aaatccttat aaggtctatt ttcttttcta
     4201 gctatttgtg caattgaatc agcaatgaaa tcagcctctt ctatttcgct accagttaat
     4261 tgtatcttta taagttctcc ttcttttttt tcactccaaa gcttttttct ttttctttct
     4321 atattattag atataacttt attagctgca tctaatatca cttgtgtaga cctataattt
     4381 tgttctaatt ttacaacatg tacattgtca taatctttct caaattcaag tatgtttctt
     4441 atatctgcgc ctctccatcc ataaatactt tggtcatcat ctccaacaac acaaatattt
     4501 tgatgttctc ttgctaataa ttttatcaat tcatattgag ctttacttgt atcttggtac
     4561 tcatctacca ttatgtatct aaatctactt ctataatatg ctaacacttc atcattagct
     4621 ttaaaaagtt ctacagtttt aagtattaaa tcatcaaagt caagtgcact atttcttttt
     4681 aaacggtctt gatataacgc ataaatatct gcaatcttaa ccattctatt atctgccata
     4741 ttgatatctt taaactgctt tggagtataa agtttgtctt ttgctcctga aattgcactt
     4801 ataactgctt ttggttcaaa cactttatca cttaaattta attcttttag acagtcttta
     4861 accaatgtaa cttggtctgc tgaatcataa attacaaaac ttctattgta accaatctta
     4921 tttatatctt ttcttagtat acgaacacag caagaatgga atgtacttat ccacatatcc
     4981 ttagtttcag gacctatgtt ttgttcaact ctttctctca tttcatttgc agctttgttt
     5041 gtaaatgtta tagctaatat atttggtgct tgtacacctt tatcttctat aagatatgct
     5101 attcttgttg ttaatacctt agttttacct gaaccagcac cagccagtat aagtactgga
     5161 ccttcagtct tttctactgc ttctctttga gcaggattta atgtatctaa attcatattt
     5221 ctcctcctgt taacagccat aaatatattt taatctaaaa tatgaattac ttcaaattat
     5281 aattatgtat tatatcaata gattatttcc aatatattac aattaaataa catttttcca
     5341 tataatttat ttcattgttt aataaaaaaa ataaccttat gatttgggga atcataaggc
     5401 acctttaagg ggtctaggtt aagggttatt atatataaat ctattttttt aaaataggtt
     5461 tagggctaat tatttatttg tattaagttc tctttctttc caatacttat acaaatcttc
     5521 ttctttctta aataaaggta aattcatatt tttatgtact tttactaacc atggggattc
     5581 tagaccagct tgtataatat tattttcatt tataaataca ttttctgcct ttccttcatc
     5641 aatcaaaatc cccttatcca atacatatat gtaatcacat atttcataca ttaaattcat
     5701 atcatgactg gatattacta tttttatatt atttttattt aatcccttta ttatatctac
     5761 gatagaccta gtgcttactg ggtctagacc agctgtaggt tcatcaagta atacaatttc
     5821 attttccatt gctataactg atgctattgc cacccttttt ttctggccat aactaagaaa
     5881 atgtactggt ctgtctataa aatctattcc attaacagct actagagctt tgtttattct
     5941 ctctttaatt gttttttcat ctataccaat gtttctcatt gcaaatgcta tatcatcata
     6001 tacttttgaa taaaaaattt gtttttctgg gtcttgaaac acaataccta cattttttct
     6061 tagattgtat aaactttttt tatcatactt taacttctct tctttaaaaa aaatttctcc
     6121 agaggtaggc tttaatatcc ccattaagtt cataaataat gttgattttc ctgaaccatt
     6181 tgaacctatt atacctataa catttccctt tgaaaaatcc atattaatgt ttaataatgc
     6241 attggcattt ttttcatatt gatacgttaa attatttatt ttaaacatca ttatccccta
     6301 ctatgtgaaa tttaccatca tacaatttta tgtctaatga tatacacata tcatcatacc
     6361 ttgtcataag tcttttgtac agcatacttc caagaattcc taaggattta tatgaagttt
     6421 ttaaatttat ataaccaaat cttagctctt gtgacttgta tatttctgaa aattcttcta
     6481 aaaatatgaa tataaaccta tatattaaca ttgataactc aacgaaagtg tcaggtaaat
     6541 gaagtttttt aaaaaagaat attaattgat taaaaggtgt tgtaagtata caaaaataca
     6601 cacaagtcaa acaagacata gctctaaata acacgtgaat agacatgtca atagacgcct
     6661 ttgatattcc tacattaaaa ctaaaaattt caaaactatg taataaatct gctttattaa
     6721 aagatatatt tacaagagtt attcctatac taagaaataa aaagtacatt ggtatcctaa
     6781 gtaattttaa atagtttttt aaatctattc cagccacaca aacaaccaga atactcatta
     6841 aaatcataat tccacttaaa ataaatatat tttgtattac catagaagca atcagaaaga
     6901 ttactcctat ggctactttt ttgtttggat ttactttact taatctattt gtatatgcat
     6961 atttatcaat tataagcatg attaacttct ctttcctttt tgaagaccta atatgtatcc
     7021 tattacacca gcacctaaag ctgcttgtgc agagaataat aaactttcta tttctccact
     7081 tggtggctca tatggactgc taaaccatgg tttgtaattt ggatttatct tagtaatttc
     7141 actttcagct tgaccatctg ctcctccata ttcagcacct gagttgacaa gtaacgggaa
     7201 tataataaga gccactacta ataaaagtaa taatatgtta gtttttgttt ttgttttagc
     7261 actcattagc tttaactcct ttatcattat tttctagtat gcttttttct ccattttctg
     7321 taattaaatt atatacaatt acagtaagta taccctctgc tattgctatt ggtatttgag
     7381 tcataaagaa aattcctaaa aacttaattg ctgaagccat cactccacct gatggatctg
     7441 gaaaagctag tgctaactgt attgaagtaa ttgtatatgt agccaaatct cctagtgctg
     7501 ctgcaagaaa tactggcatt gcattatttc catctttttt ctttaatgct ttaaatatta
     7561 aaaatgatac aattggtcct ataatagcca ttgaaaaagc attagctcct aaagtagtta
     7621 tgcctccatg tgctaatagt aatgcttgga atattaaaac tatagttcca agaacaaaca
     7681 ttacgcttgg tccaaacatt atagctccaa gacctactcc agtaggatgt gagcaacttc
     7741 ctgttactga aggtattttt agtgctgaca atacaaacac aaatgctcca catagcgcta
     7801 ataatacttt ctttttaggg tcttgcttta ctatttttcc aattgatttt agtcctacta
     7861 agaaaaatgg tataaatata actccccatg ctatagacca ttttactggt aaataacctt
     7921 ccattatgtg cattgcattt gatgtaactg gagttaaaat gattaacata agtgcagcta
     7981 taacccctaa tttgatattt tgtttcattt ttagtatccc ctctctccct ttctaataat
     8041 caaaatataa gtgatacatg tctgatttat tttaaataaa ataaaaaaac ctaactcgat
     8101 ggttaggctt ctaattttcc acaatccaaa tacaaacaca taaaacaaac atatctgtat
     8161 aattattata agaaactttc tccatccccg aagaaattac tttaatattt taggcaggtc
     8221 tcctgactta gcttcttcct aatcctcttc cttcccatga gatataaaaa atatcatcat
     8281 agtggctaac aaaagtttcg tctgcatcac agtagcgggg gctgtaaagg aatttaacct
     8341 ttttccctat taatcttgct tgaagaacct ataatattat atatttaatt tttaaattat
     8401 tcttaaattg tattctatat aaatcattgt ataccttttc tgtgaaaatt tctacatttt
     8461 ttataaattt tattcatttt tatattttta tgtatataaa ttctttttta caaacttatt
     8521 agtttctaat tatcttcttt aaatacattg aaaccacatc agaaaatcta gttatatctc
     8581 ttgaatatat aaaatcattt ccatatatca atctttcagc ttcaagttct gattctttac
     8641 ctgtaaacac tcctaatact aatatatttt gctttctagc ttttctcact tcattggctg
     8701 tatctctcag tccaactata cctctataag ctttttctcc tctcaaagtc ctctcactac
     8761 tttttcctat ctttatatca tttggtcttc catcactaag aactatcaag attttatttt
     8821 cttcatatct atttattaga ccactacata tagattttat tgccaaacca tctctattgt
     8881 taccagcaca aaaatattca aatatatttt cactattttt tagactatca tcataatctt
     8941 taaatctttt taatatagta tagtctaaaa aactagaaaa tcccattact ctatttggta
     9001 tgccaacttc tgttagagca tttgcaatta tgtaagcttg aattgccaca tttccttgat
     9061 ttctactttg agagccactt gcatccaata atatatcaat aacgtatttc cctttttcat
     9121 tttctatatc tttataaaat attttattat tattacttct accaactctc caagctctat
     9181 ttgctaatat agtaccacaa tcagaatata ctctagtttt agcattttct tctattaaaa
     9241 ttcttgacag actttctttt aatctcttta tttgctgtct atacattcta gcatgttctc
     9301 taaattttcc taaattattt tctttttgtc ttgttacata ttttagttga aatacattat
     9361 tacactcact tctaagaact ccatctgtaa agtgtattct acaaccttca tgaacacttc
     9421 tacaattttg tgtctcaatt tttttaattt cacctttact caaataagtt tttccataat
     9481 aatgttctat ttttgaatat atcttatttg cagtgtcttc atcaacatat ataactcggt
     9541 ctgctaaatt gctagatttg gaatcatcaa aatcccctac accttctaca agcatggatg
     9601 aagatatcga atctatatca ctttcaataa tattttcttc ttcatcacta taaagttctt
     9661 catacatgaa atcagcaaat gtatcaaagt ctacctctac attttttaca ttattttcat
     9721 caataagact actttcttct tcatttaata tgtattcaaa ataagttaaa tatataacat
     9781 ctaattcttt taaaacttcc ataatatctt gtttggtatc tatatttctt atatcattaa
     9841 ctattcttct agtcatacta tctaatgctg gatgcttgtc catactataa agtacaaatg
     9901 catatttaat tttatccata atattatcat tgtgtatttt ggtaaaacgt gaaacaatat
     9961 ctttataagc atttctcctt atgtcttcta ttcctggtct atctttaata gccttttctt
    10021 caactattgt atttaatatt acttgaatta gacccagtat aatatctttg ttgtatcctt
    10081 ttcttattct atttgtaaga tattttttaa ctatatccca atcaacatac tttcttctag
    10141 cacctgcaat tattgcaaaa tacagaccta tttcctttga agaataatct ttttctgata
    10201 tatctatact ctcattgtag tcgccagcta ttgtccagga taagttattg gctctatttt
    10261 caaattcata atcatcatat atccatttca taatctcacc tatattaaat atgacttatt
    10321 ggaaacacat ctatactctc ccatttatta ggtattctag ttttaattac atctccaacc
    10381 atttctttct catacacatc aaaagtcttt cctgtaagcc ccatattaat tgcaagggtt
    10441 ggttttaagc ctcttcttat ggtcttaaga gatgccataa gaccacgtaa atcaatagct
    10501 ttactagata tctcgccatt ttgagacttc aattgtaaat ctaaaaatat tcctgcaaat
    10561 tgtattaatt tttcttcatc agcatctgaa aattcatttt ttaaaatcat cattaactta
    10621 tcttcttcta taggaggaat atctattacc ataaatctag ataccaatgc ctcattaagt
    10681 tcttttgttc ctgcatattc ataattcata gtcccaataa atcttgttgc aggatgtaga
    10741 tttactctct catacccagg tacatcaatt atccttctat agtctaaagc tgaatgtacc
    10801 acaactatag catcattttt tgccatatta atttcatcaa ataccccaaa acctccatta
    10861 atagcacact cataaactga acctcttcta agtttaactt cattgtctat aaacgtatct
    10921 gtacctataa gtgttgaact atctgtgttt atatgaaatg atgtattcca ctgaggtcta
    10981 ttaaatattt cccctaaatt atcagcaagt aggttttttc ctgttgcctt tggtcctgat
    11041 aataatatat tttcttcctc taaaatcgct gctatacaca tagataatat gtcttttcca
    11101 taaaaataag ttttagacct tgttactcta tattctaaat ctttttctag accataataa
    11161 tttctaaaat acattacatc ctcaataagt ttttcatcta ccccttgtgc ccttagatta
    11221 tctattatat tcattcttct tacccctttt atataaatag tatttgtttc atttcttaac
    11281 accattttag cataaaagga tataagctag aattgatttc ataaattaat gacaactctt
    11341 cctctctttt aaaaaaaact acctatatgt actttttatg tattattttt gttaaatgtc
    11401 tgaaagttat cagattacta ttcattacag gatttataag ttgaggcttg tgaatgtatt
    11461 tgattactat atattgttct agttttgaat ttattatctt gacaatattt catctgtttt
    11521 acatcaaaaa tccccgcttt catatagaac tagaaacggg gattttgatt attataaatt
    11581 ttctcaaaca tatgaacttt agaatagctg tagaaaaaga tacaaaactt tttcatttct
    11641 tataatctta tcttgtgatg ttttttatgt ataaatgact taataacaaa tccaataaaa
    11701 attatggata ttggtataat tagaactagg aatttataat cattataatg tgacattatt
    11761 cttacccaac tctcagaaaa aatataccct atactgatta atgaagtatt ccatatggtt
    11821 attcccacga tagatgatac tacaaaagtt ataatatttt gacctgctat acctgctata
    11881 aaagatatgt atgttctaca taaagggatt aatctacata cacaaacaga aatagaagag
    11941 tatttattaa aataatcttg agatgcaaat attcctttct ttgcctttgg acatatctct
    12001 attattttat ttataataga tttacctccc caatttccca ctgtataaca aaatatcgaa
    12061 ccaagtatac ctgcaattat acttaaaatt aaaattgtca aaaatccaaa atgatttctt
    12121 gcagcaattg ctccacataa aggtaaaaca acttcgctag gtaatggaaa acaagcatac
    12181 tcaatcataa ttaatacaaa tacagagatt aatccatatt gtaaaataaa actattgatt
    12241 acagacactt acttatctat ctcctttctt atttaaaggt tttaagggta catattctaa
    12301 ggattctcac cctatattta aagaatcaat ctctttaaac tattatatgt atttacagaa
    12361 agcatttata acatacttta aaaatagtac cttaaaataa gaaacttaat aaataaaaaa
    12421 aattacgtgg ctacgtccta ctctcccagg cagtttccca ccaagtacca tcagcgctag
    12481 agagcttaac ttctgtgttc ggaatgggaa caggtgtatc ctctctgcta ttgtaaccac
    12541 ataatcttta tgcttaatat ttctattaag tttttaataa gtttatagaa tctagtaata
    12601 ctagtccttt tagagttaac actctaaaaa ctacacatat atcttagtaa gt
//
LOCUS       DAMKOJ010000092        12561 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000092 DAMKOJ010000000
VERSION     DAMKOJ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12561
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.100"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            336..1271
                     /locus_tag="PC592_002992"
     CDS             336..1271
                     /locus_tag="PC592_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDF4056934.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSDDPNGFWIILLISAIICIVITFFMSRNKLL"
     gene            complement(1363..3234)
                     /locus_tag="PC592_002993"
     CDS             complement(1363..3234)
                     /locus_tag="PC592_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDF4056935.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKIESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFIRCEKWLKSAADNNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNVEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     AKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEDFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDN"
     gene            3427..4353
                     /locus_tag="PC592_002994"
     CDS             3427..4353
                     /locus_tag="PC592_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF4056936.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTNKSFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLLLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            4492..4638
                     /locus_tag="PC592_002995"
     CDS             4492..4638
                     /locus_tag="PC592_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056937.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(4743..5267)
                     /locus_tag="PC592_002996"
     CDS             complement(4743..5267)
                     /locus_tag="PC592_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4056938.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     ESMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLARVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(5320..5544)
                     /locus_tag="PC592_002997"
     CDS             complement(5320..5544)
                     /locus_tag="PC592_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056939.1"
                     /translation="MIIKLTKDDFNFRFKQYEGMFFHAEIIESMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQIEAYIDLKSIK"
     gene            5741..6865
                     /locus_tag="PC592_002998"
     CDS             5741..6865
                     /locus_tag="PC592_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HDF4056940.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     VLSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIFLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLENNTSIQSKQHSVKELTKLYKFLIIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESKFWQKYEGKID
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(7339..8163)
                     /locus_tag="PC592_002999"
     CDS             complement(7339..8163)
                     /locus_tag="PC592_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056941.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTSVYLASTVS
                     TITKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(8511..9566)
                     /gene="ispG"
                     /locus_tag="PC592_003000"
                     /gene_synonym="gcpE"
     CDS             complement(8511..9566)
                     /gene="ispG"
                     /locus_tag="PC592_003000"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDF4056942.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(9749..10753)
                     /gene="rseP"
                     /locus_tag="PC592_003001"
     CDS             complement(9749..10753)
                     /gene="rseP"
                     /locus_tag="PC592_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDF4056943.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFWGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(10766..11920)
                     /locus_tag="PC592_003002"
     CDS             complement(10766..11920)
                     /locus_tag="PC592_003002"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDF4056944.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELVNITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYADSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(12084..12287)
                     /locus_tag="PC592_003003"
     CDS             complement(12084..12287)
                     /locus_tag="PC592_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056945.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         4193 a         2107 c         1313 g         4948 t
ORIGIN      
        1 tattcaaatt aaatataacc tatatatttt atatgtaaat tatgataaaa aaattattta
       61 atcaaatcaa aacttgattt atatacctgg aaaaggtatt atattaaaga gtgcttaaaa
      121 tacgcatttc ataaataact atataaaaaa taataaataa ggagagtgat gggcaatgga
      181 tactagtccg ttgcggagag aattttttac attctcatca cttaataata tctaaaatca
      241 aaactaatac atatattcag ttatataaat tagttaatta atagatacta ttaaatgatg
      301 agatttatat aaaactgaat aaaggatgtg ttgccatgat aagatattac aaaactatag
      361 attcaaaatt agagaaactt agtttttttg aagatggctg ttggataaat cttgttgaac
      421 ctaatcatag tgaaatcaat gaaatttcta atttattaaa tatagatgta gaaagcatag
      481 aatctgcact agatgaagaa gaacgctcaa gaatagatgt tgaagacaat catactctta
      541 tacttataga tataccagta gacgaaagtg actctaattc ttctcattat actacaatac
      601 ccttaggtat tatactgact gaagaagcta ttgtaacagt ttgtgatgca caaactaaga
      661 ttttaaacga ctttatagtt ggtcatatta aagatttttt tacatttaaa aagactcgct
      721 ttttacttca aattcttcat aaaaacgcag cttattactt gcattactta agaaaaataa
      781 ataaaatgac aatcataata gagcgagaaa tttacaaatc aatgaaaaac aaagaattgg
      841 ttcaattatt agaattagaa aaatctttgg tatacttctc tacatcacta aaatctaatg
      901 aacttgtttt aaacaaaatg gttagaactg ctggtataaa gaaatatcca gatgatgaag
      961 acctattgga agatgttata gttgaaaata gacaggctct tgatatggct aaaatatacg
     1021 gagatatatt gagtagaatt atggatgctt tcagtgcaat tataagtaat aatcagaata
     1081 atgttatgca aattttaacg gtagttacac taattttctc aatacctaca ataatatcag
     1141 gattctttgg tatgaatgtc atcaacatgc cgttttctga tgacccaaat ggattttgga
     1201 taatacttct tatttccgct ataatatgta tagtaattac atttttcatg tcaagaaaca
     1261 agctattata aaatattaat aaaaaagcca ttagaactaa ttgattttca tttatcctaa
     1321 tggctttttt atatttaaat atatataacc ttataatact ttttaattat catgttcttc
     1381 atctataatc atttcagttt caagcccttc tagcattgaa tctaaacttt cttttatatt
     1441 tagtatataa attggtacat actcttcttc atctattacc tcttcttgca acttaaatgg
     1501 aggaattaat acttcatcaa agtctatatt taaattagga aagtcctcta ctatctcttc
     1561 acaattatcg tattcttcat ttgctaaaga aatgtacata tctaggctct ttttataata
     1621 aagacctgca agcatgtact cacacttctt acttccatat ttaatacctt ctttataata
     1681 tttctcagct tctgcgtcat catttaattt taaataaatt tgacctaaat tatatattga
     1741 ttcaacacaa ccttgtgccc tagccttttc ataccaaaat ttagaattta catagtcttt
     1801 ataaaacata tcataaatta atcccaccat atgttgagca tacacattat tttcattggc
     1861 aggagtatca aacatcattt tagcctcttc caatttacct tctctaaaat aaattctacc
     1921 tagatgtata cgagcattca tatggttttt gctacttgcc atttcaaaat actttctagc
     1981 attttttgta tttcctaaac tctcataaat acatcccaat ctataactag acctcgtatc
     2041 cccattttca gatgctttct tataccaact tatggcttct tcaacattat ttaaatcttc
     2101 atagatattt cctaatttga tttgacaaga tacattattt ggaatccttg aataatacga
     2161 aatcgctttt tctatatctt gattctgata atataaatcc cctagattct caagggaact
     2221 tttgcatcca acagctatag catcctcata atatttaata gcattttcat aatctttttc
     2281 ttcaaaatat atacctgcca gattattttt tgcttctgtt atatcatctt cagccgccat
     2341 tttataataa gtttttgctt tttctatctc attttctcta ttgtataaat tagcaagtct
     2401 atacttagaa agtgtatgat ttttttctat tgctttctca taataataaa ttgcatctcc
     2461 cagttcttct tttctatcat atacatatgc aagtctatac tcagacttca catcatctct
     2521 atcagcactc tttttataat atttttctgc atcttctaaa ttatcattta tctccataat
     2581 catacccaag ttaaagcaac ctttcatatg ccctgacttg tacaactgtt tatataaact
     2641 cactgttgat ttattatctt tcttttttcc atttaatatt gctaaattat atttcgcatc
     2701 atcatctaaa agcacagaac cttttttata atattcatat gcttcatcat ctttctccaa
     2761 aaaagtatat aataccccta aattaaaaca agctttacct aaattattgt ctgctgctga
     2821 ttttaaccat ttttcacatc ttataaaatc tttcatttta aaatggcata cacctaaatt
     2881 attttgtgct tgcaaataac ctaaatttgc tatcttttca taccaatata tagcatattc
     2941 ataaccatct aacttatagt acatattacc taaatcaaaa gcagcatctt cacttccact
     3001 tttatatgcc attgaatacc acttttctgc ttctttaaat tgttttttac tttcatatat
     3061 atttcctaaa gtatattgag attttacata attatccaat gcagcactct tatacaactc
     3121 tattgcgctt tctatcttac ccatcttttc aaggagggca cccttagtat gtacgacttt
     3181 cgggtcatta gatatatttt ttattttttt tatagaaaat tttgtatttt tcattattcg
     3241 ctacctaccc attttataaa atatattctc tcaaacatta ttatacatta taatctataa
     3301 ttaatgctat aatattgaat ttttaccttt tgtcactata ttgtaacatt aaattttaaa
     3361 ttttataatc attagatttt attatgtaat tggtatataa tgtatatata aggggaggga
     3421 cattttatga atttcagcaa tatttttatt caagttgcag ttttatttat aattatttta
     3481 gttgggtatt ttgtcagaaa attcaactta ttagatgacc actgcacatc taagctttca
     3541 actttgacaa tgacagtttt tttaccctca atgataatta gctccatgca aattaacttt
     3601 gatagtaaaa tgatacaaaa aatactattg ttattattta catctttgat tatgtatata
     3661 gtttcaatta taattgcatt tttgttaaaa tacattttaa aatgtaatga taaaaaagat
     3721 ttgggaatat atcagtatat agttgttttt tcaaatgttg cttttatggg ttatcctgta
     3781 attgaagcag ttctaggtca tgaagcaata ttctatactg caatattcaa tttgcctttt
     3841 aacttatttt ctttcacttt aggaatttat cttttatcta aaggcagtac aaataaaagt
     3901 ttttcaataa aatcacttat aagccccgct acaatagcta ttgttattgg acttttttta
     3961 tttgtaacag gacttaggtt accccaattt ataaacgagc cacttgagat gttgggaagt
     4021 ataactacac caatatccat gattattatt ggaagtttac ttgctaattc ttcagctctc
     4081 gattgttttg tcaacaaaaa attatatata gtcactttta taagattatt gctgcttcct
     4141 gtgattgtat attttattct aaaaggatgg ataaatgata agatgatttt ggctatacca
     4201 gtagtaattt cttcaatgcc tgctgctgca aatactgcta taatggctaa tcaatatgac
     4261 tccaatataa cactagcttc acaatgtgtg ttttttacaa cactattttc agttatatct
     4321 atacctttta taagtatttt actcttatct tgatttattt ttttatgtat tatataataa
     4381 catattcaat aaattacaaa tataaacatt ttattgtagt atattgatgg aattttttcc
     4441 tagatatttg tcaataatat ctatatgtat tatagaatag gaggcttaaa tatggatatg
     4501 gatttactct ttaaaatagt atttgctata gttgctatag gtgtttctgt aaaaatcatc
     4561 aaaactgttg ctagtttagc ttttaaaata gcgttgatat tgctaataat tttatttgta
     4621 tatagaatgt ttttgtaaac atttaaaaat aagtttttta ataaaataga gaagtaaaat
     4681 agattatctt taatgtaaat tttttattaa agacactcta ttttacttct ctattagttt
     4741 ttttaaatta aatttttatt atatcttccc ataatataaa catcttcaaa ttttccatct
     4801 ctgattacag catatttttt agttccctct atttcaaaac ctagtttttt atataaattt
     4861 aatccctttt cattatccac aattacttct aatcctactc tagctaacat aatccaatta
     4921 tctgctatgt ctaaaagttg ttccataagc tttttaccta ctcctcttcc ctgataattc
     4981 tctgcaacac ttattcctat ttctgcacta tgtctcaatc gtggagaaga atttacatgt
     5041 aacccagcaa agcctattac atctttttct ccattattat tagtttcagc tacaaacata
     5101 taatcatttt ctcccaaaga agctaacata gattcagttt tatcgactct gtcactcatt
     5161 aatgccaaag tatttctcat aacactgtat gttcttctaa tttcattaaa agcttgtgca
     5221 tcttctcttc ttataggtct tattgttata tctataggct tactcatatt ggattccccc
     5281 tcaaacataa tctttatttt taattaaaat tttacatctt tattttatac ttttcaaatc
     5341 tatgtatgct tctatctgag gtacatatat catattatct tttatatgtg tactcccaaa
     5401 ttcttttaat tctgtacctt ctttatcctt agttatttta tatctgatgg attccatact
     5461 ttcaattatt tcagcatgaa aaaacatacc ttcatattgt ttaaatctaa aattaaaatc
     5521 gtctttagta agttttatta tcatattttt atctactcct tatataatta atatttttct
     5581 tattattagt tgtatacata ttgcttattc atattaatat attataactt atcatttatt
     5641 tagtataaag ttataaatag atatatttat acttatttta caatctttct tcaattgata
     5701 tataatatgt ttatataaac taatgtatgt gaggtgaaat atgagcaaaa aaacaaaata
     5761 tttttcttta attctctttc ctattgcttt gcttttaaat tttatagcca gcaaagttcc
     5821 aaatattgtt gaaaaatatt actcccaatt tatagataaa ataattgtac aagtattgag
     5881 taaagtttca ggaatttttc cattttctct ctatgaaatt acaatgtaca taatagttat
     5941 atctatcttc ttatttttat gttgtacttt atctacaatt tttaataaga aaaaaaaatt
     6001 aaacatattt ttaaaaaatt ctattttaaa tatattatcc attgtatcaa tagtctactt
     6061 tctttttgta gtgctttggg gaataaacta taataggatt ccactagaaa ccacacttat
     6121 aaataactat aatttagaaa acaatacctc tatccaatca aaacaacata gtgttaaaga
     6181 gcttactaaa ttatataaat ttcttataat taaagcaaat gaaactagaa aactcacatt
     6241 acaagataaa aatggtattg taaaatctaa tacagattat aatggtgtta taaatagagc
     6301 tcaactagga tacgataata tcttggatat attacctagt gttagtggta gttattctaa
     6361 gcctaagtat attatttcat caaatctaat gtgctataca gggataactg gcatatactt
     6421 tccttttaca ggtgaggcaa atgtaaatat agcaatacct gacttgtata ttccttgtac
     6481 agttgaacat gaaatggcac atcaaagggg atttgctagt gaagatgagg ctaattttat
     6541 agcgtatctt acttctataa aacaccccaa tattgatttt aactattctg gatatatttt
     6601 agctttaaat tatactgctt ctgctttaag taaggttgat tataatgcat atgttgatat
     6661 ttctgctggt atttcagatt ctgtccgtag agatttaaaa aatgaaagta aattttggca
     6721 aaaatatgaa ggtaaaattg atgagatttc taatgagttt aacaattctt acttaaaagc
     6781 taatggcgtt actgaaggca ctcagagtta tggtaaaatg gttgatttat tgctaactta
     6841 ttatgaatta tatccatata actaaacact acaattcaaa actttattca tatacagctg
     6901 gtattaaatc agctgttttc tatttaaata aattatttag ctccaagcaa tcttatataa
     6961 tttgaaaata cttatactat ctgtataaca tttcaattct aactatttta gttaaaacat
     7021 ttctattatc ttttttaata aatattttaa ctaaaatttt taaaacataa aacttccaca
     7081 ttatttcact atctatataa aaagataaaa atttacatat aaaattacat aactaaaaaa
     7141 tcataaattt atagaaaaca tatattcaaa ataaaaaagc atgtatcaaa acttgacaca
     7201 tgcttataat cttatgtata tatgccattt tgtcacaata aaaatttcct tgtaacactg
     7261 acatttttaa acaaaatagt tcttatttaa ttaaattaac attagttaaa ttcgtactta
     7321 ttttactatc attaaacatt acttatagta attttctaat acactatttg aaacttcctt
     7381 cccttgaaaa cttttcaacc aattctcata tgctgaattt ttccatacac taccatcatt
     7441 aaatgttact tgttttacac aagatataat gtactttaca ccatgctctc cagttgattg
     7501 tttccattta tcaaacaata aaaaagcatc attttgattc ttacctggtg ctattgcatt
     7561 ttgctttgca tattctttct ccatttgttt ccattctttc aaccaatttt ctacccatgc
     7621 cttgccttgt tgtttttcaa acatacttat tatatcctgt ggtggtgatt gttgcatttt
     7681 tctataagta tgtgaatatg attttggaga cacaggagat atgcctgtaa caataccata
     7741 atctacacca gctgggctaa acccaacact tcctacttcg ccatctgctg ccacattttg
     7801 agcatcccag tatagctcaa gtggttttcc atttttatca tatgctaagc acgtaatttc
     7861 ataatccata attgcttttt cactgctatt tgttaagctt ataacattgc taggccaatg
     7921 atatggagta tcatcatact gtattttgct attatttata aataatggaa tattttcatt
     7981 gtaaacaaga cctttactac tttgaatatc tgatactttc tttgtgatag tacttactgt
     8041 acttgctaag tatacacttg ttttttctga attggtcgta ctaagagaaa atgttgttgt
     8101 cgttccagta atcagcaaag caacaactaa aataggtaag ctagatattt ttttatatct
     8161 cacagttctt caccccttct tctattaact tataataaaa caatttacca aaacattaaa
     8221 atctatgtta acataattta ccagatgttc tagtaactat atcctatcat agttactatc
     8281 aagtttcaat actattgatg gaaattttca ctatattaaa tcttttttta attttataaa
     8341 tttacaatat aatttaactc atacatatat agtcaaatta gagtataagt ttcttacatt
     8401 taatgaagtt tataaaataa aaaatgacta gataattaaa tactgtaaat aaaaactcat
     8461 tacaaaagta tttaaaaatc tagtcaatta atatatatct aaattgtata ctataatttc
     8521 tcaatctctt ctagcaactc atcaactaat ttgttaccat caatcattct cactatttca
     8581 ccctttttaa ataaaaggcc ttcaccttta cctccagcaa tacctatgtc tgcttctctg
     8641 gcttcaccag gtccatttac agcacagccc ataattgcaa cagtgatatt tttttccata
     8701 ctaccaatct tttcttcaac ctcatttaca acactaatta agtctatatt acatctacca
     8761 catgtaggac atgatataac tttaatctta tcatttaaaa gtcccaaact tcttaaaatt
     8821 tgtttaccaa caataacctc ttcaacaggg tcacctgtta aagatattct aacagtatct
     8881 ccaattcctt taagaagaag tgctcctacc cctatagaag actttattgt tcctttgtga
     8941 acacttccag attctgtaat tccaatatga agaggataat caactttttt tgatattaat
     9001 tcatatgcat caacagtttt ataaatatcg gatgatttta gagatataac tatattatga
     9061 aaatctaagt cttcaagaat cttaatatgt cccattgcac tttcaactaa tgcttcagca
     9121 gttgcagagc catacttttt taaaagttct ttctctaaag aacctccatt gactccaatt
     9181 ctaattttta aatttctttc cttgcatttc tcaactacca tcttaactct ctctatactt
     9241 ccgatattac caggatttat tcttattcca tccacacctt gttctatagc ttcaagggct
     9301 agcttataat cgaaatgtat atctgcaata attggtatat ttacactaga ctttatcttt
     9361 gctatattct tagcagcttt aatatcagga acagcaactc taactatatc acaaccagct
     9421 tcctctagtc tctttatttg agctattgta gcatctgcat ctcttgtatc agtatttgtc
     9481 atagattgta tacttatagg attttctcct cctattttta cagttcctac acttacttct
     9541 ctcgtctttc ttctctcgta actcatattc cacctctata tattatttta tattgaatct
     9601 ctttaaatat taaaatatta taacctacat gtatattata aattaaaaag ctatctagtt
     9661 aaataagaat aaatttcata cataaaaatt aatttattct tatttaaaac tacatagcct
     9721 attttcttaa aatctctaaa aaactaaatc attgaaataa tcttagtata tctttatatg
     9781 tgataaaaag cataaataac attaaagctc caaaaccaac aacatttatc atgccttctt
     9841 tatttgggtc aagtttttta ccacctctaa cagcttctag taatagcata agtattctcc
     9901 atccatcaag cgctggtatt ggtaatagat ttactatacc taaatttaag cttatgacag
     9961 ctgctaaata cactacattt atgatgcctg tacgagcagc atccgatacc ataccaataa
    10021 cacctactgg tcctgctaca gcattgccaa tccctcctgg tacacgtcct gtaatcattt
    10081 gacctagaaa tgttagcatc tgttttgtca tatctacagt agttttacat gcatttacta
    10141 ttgaccccca aaagtctttt tccctttgtg gttgaatccc tatttcatac tttccattgt
    10201 tatttttagg tgttacattt acaactttat cacttccatc tctagttata ctaagtttta
    10261 attctccacc agaagaagtg tttattatat ttgcaacttc atcccaagtc ttaacagaat
    10321 taccattaat tttatttatc ttatctccta cttgaagccc tacagcctgt gcaggagtat
    10381 ctggcattat ctttcctaat ttagtcgttg gagaacctat atacaaaaat actggtacta
    10441 aaagtattgc tgctaatatt atattgaata ttggacctgc tacaatagta ctaaatcttt
    10501 gtaatataga cttgtttcca aaagaatttg gacttatttg ctcttcatct tcaccttcca
    10561 tactgacata tccaccaatt ggaagtgctc ttatagaata ctctgtatct ttttttacac
    10621 tatatatctt aggccccata cctatagaaa actcatttac tttgatacca cttctttttg
    10681 caaatataaa atgtcctaac tcatgtatta atacaattat actaaatagt attaatgcgg
    10741 ctattatagt cataaattca ccttcctatt tttttatcag atttgcaaca taagctctac
    10801 tccatctatc tgtttctaag atttcttcta atgttggttc acttatgcta ctatgaactt
    10861 ctaaagtctt ctctatgtaa tatggtatgt catagaaacc aattttatcc tctaaaaatt
    10921 cacttactaa aacttcattt gctgaattta aaacagaaga ataagttcct cccattttta
    10981 aacactcata tgccaatttt aaacatggaa aagtttctaa atctggttct tcaaaagtta
    11041 aagtactaaa ttttgaaaaa ttcattcttt caaagctact ttccattcta tctggatatg
    11101 taagagcata ctgtattggt agtctcatat ctggacatcc taattgagca attattgagc
    11161 tatctgcata ctgcaccatt gaatgaatta tgctttgtgg gtgaactact acatcaatat
    11221 tttcttgttc taccccaaac aaccatctag cttctatcac ttcaagtcct ttattcataa
    11281 gcgttgaaga atcaatactt atttttcttc ccatactcca atttggatgc ttcaaagctt
    11341 catttttagt tatatttaca agttctccct ttttctttcc tctaaatgga ccaccagatg
    11401 ctgtaagtat tatcttttct atattttttt tattttctcc atttagacat tgaaatatag
    11461 cactatgttc actatcaaca ggaagaatat ttacattgta tttttctgct tctttcatta
    11521 caagttcacc agcggttacc aacgtttctt tattcgctaa tgctatgtct attcccttct
    11581 ttatagcaca aagagttggg actaatccta tcatacctac tacagcagtt aaaaggacat
    11641 ccacttcatc aagtgatgat attattttta atccttccat tcctgctaag acttctattt
    11701 ctatattttt aggcaacatt tcttttaatt tcaatgcttt attttcctca aaaactgtta
    11761 catatttagg tttaaactct actatttgtt ctagcaataa ttcaatatta ctgttagctg
    11821 atattgcaac tatctcaaac ttatctctat gttctctaac cacatccaaa gtttgtttac
    11881 ctatagagcc tgtagaacct aaaattgata tctttttcat ataataatcc tttctaataa
    11941 taaatatacc ctatcaaaac attataacac tactaaaaca attattttta ctattcatag
    12001 aaatttcata tattattcca cagattaaaa ttaatctatt attttttgta ttttgtggaa
    12061 tattataaaa tattctagta tcattaaatg ccctttttta tttccacaac atcttctatt
    12121 ttacagtcta gtgctaaaca tatcttctcc attgtatcca tagaaacaga tttatcattt
    12181 cctagtctgc ctaaaacaga aatacttata cctgatatat ttacaaattc cattttcttt
    12241 atttttctgt caattaacaa tttccataat ggagcgtatg aaatcatgtt atcacctcgc
    12301 aaaatatatt ctatcacatt ttatctattt tggaaaatat tcatctattt ggttaaataa
    12361 tcacctgatt aagtgtcaaa taattttatc cttctaatat gaaaaattaa tactatacta
    12421 aatgattggt ctataacaca tatgatgcat tattattaac atataaaaat ttttattggc
    12481 gctaaattaa agtaatatac tattattata tttgcagata tataagaaag attttattat
    12541 atatttaaag tacttgatta t
//
LOCUS       DAMKOJ010000093        12521 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000093 DAMKOJ010000000
VERSION     DAMKOJ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12521
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.101"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            208..897
                     /locus_tag="PC592_003004"
     CDS             208..897
                     /locus_tag="PC592_003004"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDF4056946.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            898..1470
                     /gene="yqeK"
                     /locus_tag="PC592_003005"
     CDS             898..1470
                     /gene="yqeK"
                     /locus_tag="PC592_003005"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDF4056947.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDALRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            1587..1937
                     /gene="rsfS"
                     /locus_tag="PC592_003006"
     CDS             1587..1937
                     /gene="rsfS"
                     /locus_tag="PC592_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDF4056948.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            2291..4711
                     /locus_tag="PC592_003007"
     CDS             2291..4711
                     /locus_tag="PC592_003007"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDF4056949.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            5052..6113
                     /locus_tag="PC592_003008"
     CDS             5052..6113
                     /locus_tag="PC592_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056950.1"
                     /translation="MYQRIIFPMLKREVNIPGNLNYQYKYNGVKESKSVKTSWEFKDE
                     DKRKFRLMCLPNSKTVSAIINDLIYFHSTEEYKLQFIGMRMNVLVDIWAHMYFIGKPE
                     WYINDIKEFIAEESKYIAENKWTKSEEYRNGWHAINVSGTLDACGYESISYLGYGRMG
                     NVPDYGYLNYRYVPNWSCTDDKVKIQKNNQDNFFKAFCQMFYALKCIKNGNDFNINQY
                     DNLTAQQKTEVTKVIATRKTDQSDAWEKVIKVLGYSSLEKFDKNKWKNEFEKFSNKKK
                     INYYYFNLVAKKHIDYVNNFLEENRLKLDGMCSEYCELKVFDDTQFAKNKNRVIKIVL
                     RGDFIVDAIQLVYDGKCKT"
     gene            complement(6842..7402)
                     /locus_tag="PC592_003009"
     CDS             complement(6842..7402)
                     /locus_tag="PC592_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056951.1"
                     /translation="MKLRNPKIKKLLSVALLAPLVGIPIGQTANAMEISNDIPSYIEN
                     NPITIEINDSQLPKPGTVTYIDMNKLIKNLKENGIDTTIIENELYYRKAGTNKIVWTK
                     MGFDLYLSKGVALTLAGAGTGVAGILAGAIPGIGQYLAAAIVGAITMHLGSNITSGKI
                     FKFKKMRYNKGGTYVTKYYLQSVRNQ"
     gene            7840..8511
                     /locus_tag="PC592_003010"
     CDS             7840..8511
                     /locus_tag="PC592_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056952.1"
                     /translation="MKKYIRYQSRSELKQLRKLFEYKIDDIVGYLFCSRRTFERIERD
                     NGTSNICLANRIAELYFQRFDELFIEVDLEVIKFINSIREYTLSIEDSYIIENEIYYC
                     IFLKKLDTCRDQIWGSTYWLEDYNKYKDIRKLREANVAYLLKNTNHKITIINTENQWY
                     RIYFGLCIGKFHEILISKSCAEKCVPYILKRHVVESSLLFNNSKISDLMLLGKYDDKR
                     NILID"
     gene            8706..8900
                     /locus_tag="PC592_003011"
     CDS             8706..8900
                     /locus_tag="PC592_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056953.1"
                     /translation="MKGGEYMKTLMFVFVIMYYITIVIKSITTIVKSITRLLDSISRL
                     KESLHKLRNRPDGNQDDFNK"
     gene            9403..9492
                     /locus_tag="PC592_003012"
     CDS             9403..9492
                     /locus_tag="PC592_003012"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4056954.1"
                     /translation="MPPMATMKKICLALDCNIEDIVEIKKDED"
     gene            complement(9679..10674)
                     /locus_tag="PC592_003013"
     CDS             complement(9679..10674)
                     /locus_tag="PC592_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDF4056955.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTNNLDEIKDFFEKGIYC"
     gene            complement(10795..12423)
                     /gene="aspD"
                     /locus_tag="PC592_003014"
     CDS             complement(10795..12423)
                     /gene="aspD"
                     /locus_tag="PC592_003014"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HDF4056956.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAINETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFIHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKNASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT         4858 a         1509 c         2034 g         4120 t
ORIGIN      
        1 tttgtatgtt atattttatc aaaattaaga caaaatagta aaaagttatt tttattaaaa
       61 agtaaagtgg aatcatgtta aataattatt ttttaaagcg ttttttagca tataaatata
      121 attatatacc aaaaaaaaca aattataagc tttaagaaat aaaaaataat ggtacaatag
      181 tattataaca ttaaaaggag acaaaatatg agaagcgaaa atctagttaa gatggcagag
      241 ttgaaaaata ctgaaaaact agagaaattt aatcgccata aaggcaaaat caaaataggt
      301 atattgggag gtacatttga ccctatacac tatgctcatt tagcaacagc agaatttatt
      361 agagacaagt atgacattga caaaataatc tttataccat caggaaatcc accacataaa
      421 ttatgtatca ctacagataa gtatgataga tataatatga cacttctagc aactgaaagc
      481 aacgaagatt ttttagtttc aaaagtagaa atcgaaagaa agaaaaggac ttatacaata
      541 gatacattaa aatacttaaa gaaaaaatac aaaaatgcag acatttattt tataacaggt
      601 gcagatgcga tttgtagtgt tgaagagtgg aaagatgtaa agaaaaactt tgagttagct
      661 acttttatag cagcaactag accaggaatt agtttgttaa ggtcacaaga gactatagaa
      721 aaactaacta aaaagtataa tgctgacatt ataacagttt atgttccatc actggatata
      781 tcgtccacat atataaggga acagctaaat gaaggcaagt caatacgtta cttagtaccc
      841 gaaaatgtag aaaattattt atatgaaaat aaactatatc aatatggaga tgattaaatg
      901 aacttagaaa atattaacca gaggctaaat caaatgctac cagtggggag gcttagccat
      961 tcaaaaaatg ttgcaaaatg tgctgaaaaa ttatgtgaga tttatggatg tgacaaagag
     1021 aaagcttact tagcaggaat gattcatgat tgtgcaaagt atttaagtga caaggaaata
     1081 gaggattatg taaataagta tgaaatatat ttagacccaa tagaggatgg aaaccgttcc
     1141 ttgtctcata gtgtaattgg ggcatacata tgcgagtatg agtttgaagt agaagatgaa
     1201 gatattataa atgcaatcaa atatcataca acagggagag aagatatgtc tcttttagaa
     1261 aaaataattt acatagctga tttgattgaa gaaggaagaa aattcccagt tgtagatgca
     1321 ttaagagaat tagcatatgg aggtaaactt gatgaagcac ttttaacttc ttttaataat
     1381 actttaatgt ttgtcatcaa taaaaaagaa gagatacatc caagaacagt tatggcaaga
     1441 aactatctaa ttaaagaaaa gttattataa aaaacctata taaaggtaaa catattaata
     1501 aatttaaagt tgactatgtt acaaaatcgt attaatatgt tacaataact aagtgtattt
     1561 taattaggaa agtgaggaat ttttatatga cagtggaaca aatgacaaaa atagcatatg
     1621 atgccataga agataaactt ggtcaagata cagttataat aaatatagga aaagtttcta
     1681 gtttgtgtga ttattttatt attactacag catcttctca aagacaggta aaagctattg
     1741 ctgacaatgt ggaagatgaa ttggcaaaac taggattaga gccaagaggt aaggaaggac
     1801 aagggactca aacttgggtg ctccttgatt atggagacat aatggttcat gtatttaatg
     1861 aggaaaatag agggttttat aatttagaaa aattatggaa agatgcacct tatatagata
     1921 ttgacacatt agcataaaca tgataatata tgttattata attagaaaat ttcaaaaatt
     1981 atattaaatt gaatagacta gagcagtaaa agattatatt ttttcagaga gttagtggaa
     2041 ggtgagaact aatattatat aactttgaac ttactagatt aaaatctatt ctccatggct
     2101 ggattaaaag ctatctaaga gggtctatgt atatagtaga ctaattaggg tggtaccgcg
     2161 aagatttatc ctcgtcccta aacgtaagtt tagtgacgag gattttttat tttcaaagaa
     2221 ttatttggaa attataagta aataatacta aacaaggtag ttatacacaa ctaaaaatag
     2281 gaggtaaaat atgagcgtat ataattttaa agaagtagaa tcgaaatggc aaaaaatttg
     2341 gaaagacaat aaccagtata aaatggatac tgcacaaact gaaaaaccta attattatac
     2401 attagaaatg ttcccttatc catctggaaa aatacacatg ggacatgtta gaaattattc
     2461 tataggtgat gttgtcgcaa gattcaaaaa aatggaaggt tataatgtac ttcatccaat
     2521 gggatgggat tcttttggat taccagctga aaatgcagct ataaaacatg gaatacatcc
     2581 acataaatgg acaatggaaa atatagaaga aatgaaagag caattaaatt tattaggtat
     2641 tagttacgat tgggacaaag aagttgcaac ttcaactcca gaatactata gatttacaca
     2701 agaaatattt ttgaagtttt tagagcatgg gcttgcatat aagaaaaaat catatgttaa
     2761 ctggtgtcct tcttgtgaga ctgttcttgc aaatgagcaa gttgttcaag gagcatgtga
     2821 gagatgtaaa gcaacagtat taaagaaaga cttagaacaa tggtatttta agactactga
     2881 atttgcagaa gaattgctta atgacttaga tacattagat ggatggccag aaaaggttaa
     2941 aacaatgcaa aaaaattgga taggtaaaag tacaggagca gatttagttt ttgatataga
     3001 tggaactgat aaatctatga cagtatttac aactagacca gatacaactt atggagttac
     3061 ttatatggta cttgctccag agcatgaatt agttaaagag ttggttgcag gtactgaata
     3121 tgaagcagat gttgaagctt ttgttcaaaa aatgcatact atgacagaaa tagaaagaac
     3181 agcagctgat gtagaaaaag aaggaatgtt tataggtaga tatgttataa atcctttaaa
     3241 tggtaagaaa gttcctttat ggatagctaa ttatgtatta gttgagtatg gaacaggtgc
     3301 cataatggca gttccagcgc atgatgaaag agatagagat tttgctgaaa aatacaattt
     3361 agatataatt gatgtaataa cagaagataa caaaatgata aattcggaag agtttaatgg
     3421 attagatgct tcagaaggat ttgaaggaat aatagataag ttagaaaaag aaggtagagg
     3481 aaagagaaca attaattata gattaagaga ctggttagtt tcaagacaaa gatactgggg
     3541 ttgtcctata cctgtagttt attgtgatga atgtggaata gttccagtta aaaaggaaga
     3601 tttgccagtt cttttaccaa cagatgttga atttactgga aaaggtgaat ctccacttac
     3661 tacttcaaag caatttatgt caacaacttg tcctcactgt ggaaaaccag ctagaagaga
     3721 agttgatact atggatacat ttgtagattc ttcttggtat ttcttaagat atgtggatag
     3781 taataatgaa aatgaaccat ttagcaaaga attagttaat agatggcatc cagtagacca
     3841 atatataggt ggagtagaac atgctataat gcacttactt tatgcaagat ggtttgtaaa
     3901 ggcatttaag agtatgggga tggtagactt caatgagcca tttaaaaact tacttactca
     3961 aggaatggtt cttatggatg gttctaaaat gagtaaatct aaagggaaca cagtatctcc
     4021 tatggatata atagatgagt atggggcaga tactgcaaga cttttcgtat tatttgcagc
     4081 accaccagaa agagatttag attggtcaga gcaaggtgtt gatggatgct ttagattctt
     4141 aaatagagtt tatagattgg ttgacgagtt ggcagacgtg gttaaaaaag atgtagaatt
     4201 tggagaatta aattctcaag ataaagatat gagatatact atacactcta cacttaaaaa
     4261 agttactgct gatttaagtg aaaaatttgg atttaatact gctatatcag ctcttatgga
     4321 attaataaat gatatgtata aatataaaga gttagataat ataaacgaag cagttataaa
     4381 agaaggtgta caaactatag taactataat tgcaccattt gcacctcatt taggtgaaga
     4441 actatggact atgataggta aagaaggaag tgtatttgac atagactggc ctaaatatga
     4501 cgaaaaagct ctagtaaaag atgaaataga ggttgttgta caagttaatg gaaaagttag
     4561 aggaaaatta actgttaact caaatatatc taaagatgag atggaaaagg tagctttaga
     4621 agatgaaaaa ataaaaggat tagttgaagg taaaactata gttaaagttg ttgctgtacc
     4681 taagaagtta gttaatatag ttgttaaata acttaaaaat ataaatttat aaaataaagg
     4741 aggctgtctc aaaatagaga taagcctttt ttcattgttg aaattataaa aatagatttg
     4801 atttcataca agaaaagttc ctaatgaact aaaaagttca ttctgagaca ccctcatttt
     4861 catcttgaaa attattacaa ttaatgttaa atatcgtgaa tacattgaga gagtatttgc
     4921 tgtgacttct gtagatatta aagtataaga agaaataaaa gaatattaaa gtaactagaa
     4981 gaatataaag cgtaggtaaa atatgtaaga attatatgct attgtaactt acaatttata
     5041 gagtggagtt tatgtatcaa agaattatct tcccaatgct aaaaagggag gtgaatatac
     5101 ctggaaattt aaactatcaa tataaatata atggagttaa agagagtaaa agtgtaaaaa
     5161 caagctggga atttaaagat gaagataaga gaaagtttag gttgatgtgt ttaccaaata
     5221 gtaaaactgt ttctgccatt ataaatgacc ttatttattt tcatagtact gaagaatata
     5281 agttacaatt tattggaatg agaatgaatg tacttgtaga tatctgggca cacatgtatt
     5341 ttattggaaa accagaatgg tatattaatg acattaaaga atttatagcg gaagaaagta
     5401 aatacatagc ggaaaataaa tggactaaat cagaagaata tcgtaatggt tggcatgcta
     5461 ttaatgtttc tggtactctc gatgcttgtg gatatgagag catctcatat cttggatatg
     5521 gaagaatggg gaatgtacca gactatggat atcttaatta cagatatgtt ccaaattgga
     5581 gttgtactga tgataaagtg aagatacaaa aaaataatca agataatttc tttaaagcat
     5641 tttgccaaat gttttatgca ttaaaatgta ttaaaaatgg aaatgatttt aatataaatc
     5701 aatatgataa tctaacagct caacaaaaaa cagaagttac aaaagtaata gcaacaagaa
     5761 aaactgacca atcagatgca tgggaaaaag taataaaagt tttaggatat agttctttag
     5821 aaaaatttga taaaaataaa tggaaaaatg aatttgaaaa attttctaat aagaaaaaaa
     5881 taaactatta ttattttaat ttagtagcca agaagcatat agattatgta aataattttt
     5941 tagaagaaaa tagattgaaa ctagatggaa tgtgtagtga atattgtgaa ttaaaggttt
     6001 ttgatgatac ccaatttgct aaaaataaaa atagagtaat aaaaattgta cttagaggag
     6061 attttatagt tgatgctata cagcttgtat atgatggaaa atgtaaaact taactacatg
     6121 gagaaccttt tggaggtatc atagtggata tggatttaga tgcggatgat tatataatta
     6181 aaataagtgg ctctataggg tggtttacct ataccagcta gaacaatagg taaaataact
     6241 tttttaacta aaaaaggaaa aactatagca acaggaaaag aacgagcatt taagaaatat
     6301 ggaaacttta ctctagagcc agaaccaggt aaacaaatat ttgcccttca gggttcctac
     6361 tcaatatata aatttagttc atagtatagc aaaagatatt tagattctct agggattgct
     6421 tgtatgaaat aattatataa aaaaatattt aaaattcaaa ttagaagttt ttgtttaata
     6481 gatatattag aaggtagcaa ctagttagtt gttactttcc tttttaattt aatcagtttt
     6541 tacagcgttt ataatataac aaccaattca tatattagat ttacttttcc gaataaaagt
     6601 atggcagtat aacaagtatc taaaatatta caaatattaa atgagaaaaa gatggtaagt
     6661 taactccacc atcttatttt ttatctatta atgaatgatg ctacaaaagt cagtataaaa
     6721 aatgaaacaa acaatataat gaacttgtgt aatttactta gttgaaacac tttattagaa
     6781 acgaataaaa ttaatgctga tacaattgca aaaagtagat attttataat cattttatca
     6841 cctattgatt tcttacagat tgtaagtagt atttggttac ataagtccca cctttattat
     6901 aacgcatttt tttaaattta aagatttttc cagatgttat atttgaccca agatgcattg
     6961 taattgctcc aactatagca gcggcaagat actgtcctat accaggaata gcaccagcca
     7021 aaatacctgc aacccctgta ccagcaccag ctaaagttaa tgcaactcct ttagaaagat
     7081 ataaatcaaa gcccatctta gtccaaacta ttttatttgt tccagctttt ctataatata
     7141 attcattttc aataatagta gtatcaatac cgttttcctt aaggttttta attagtttat
     7201 tcatatctat gtatgtaact gtgcctggtt taggtaattg agagtcattg atttctattg
     7261 ttattggatt attttctata taacttggga tgtcatttga aatttccatt gcattggctg
     7321 tttgcccgat aggtatacct acaagaggtg ctaataatgc tactgataac aatttcttaa
     7381 tctttggatt tcttagtttc ataaaatacc tccattttaa attagttata tatcaaagat
     7441 atatattatt attgtagaat atagttatta ataattaact atattaaata ttaataaaaa
     7501 atatagtaaa acttaagaat acatacaata aaacttaata taaattaagt ctatgatata
     7561 aagatggaag tgtactatca atatatcttt gctaaatcaa ctgttatcaa agagagtatt
     7621 cttcattttg aaaggtgatt ttcaaatata agaagtaata atatttatat tcttaaaaaa
     7681 gtaatatatt tttaaagttt ttagcaacag gggacctttt agaaaaaagc tgcaagagtt
     7741 gataatgcta atgttcatgt ataaaatcta caaaaataaa atgtcgtagt aaaaaaagaa
     7801 taaaactatt aaactaaaat caggaggtga taataaaata tgaaaaagta tataagatat
     7861 caaagtcgaa gtgaacttaa acaacttcgt aagttatttg aatataagat tgatgatatt
     7921 gtaggatatt tattttgtag tagaagaaca tttgaaagaa tcgagagaga taatggaact
     7981 agtaatatat gtttagccaa tagaattgct gaattgtatt ttcaaagatt tgatgaactg
     8041 tttattgagg ttgacttgga ggttattaaa tttattaatt ctattcgaga atatacttta
     8101 agtattgaag atagttatat tatagaaaat gaaatatact attgtatttt tctaaaaaaa
     8161 ttagatacat gtagagacca aatatgggga agtacatatt ggttagaaga ttataataaa
     8221 tacaaagata ttcgcaaatt aagagaagcg aatgtagctt atttacttaa aaatactaat
     8281 cacaaaataa caattataaa tacagaaaat cagtggtata gaatatattt tggcttatgt
     8341 attggtaaat ttcatgaaat tcttatttct aaaagttgtg cagagaaatg tgtgccgtat
     8401 atattaaaaa gacatgtagt tgaatcaagt ttattgttta ataactctaa aatatcagac
     8461 cttatgttat taggtaaata tgatgataaa cgaaatattt tgatagacta aacattacat
     8521 tttataaata aaacggtaat atttattttt tggaatcaag gatataaaaa atatataaat
     8581 taattaagaa taaacaagaa taaatatttg gtaattataa aattatgtta taattaaaat
     8641 tcaagaataa tcttgcaaga gactacaatc taagggcgaa agttttcagg tacaatcacc
     8701 ttcgtatgaa agggggtgag tatatgaaaa cacttatgtt tgtatttgtt ataatgtatt
     8761 atattactat tgtaataaaa tctattacaa caatagtaaa gtctataaca agattattgg
     8821 attctataag tagattaaaa gaatctttac ataaactaag aaatcgtcct gacggcaatc
     8881 aagacgattt caataaataa atcattactt aaattatttt gaatttgaaa cttcgctcta
     8941 ggctaataga ttgtagtttc tttttttgtt tttgatacta tttcatacct ttattgtata
     9001 tcaaatcgtc aatgatgaca atactgacaa cattgacaat tttatatagt tgtaaattat
     9061 ttttatatgg aataaattag gaaaatataa tttgaatatt ctaatttatt ataaaaaata
     9121 tttgttataa tattacatat gatttagtat gtaagaattt agaaaaaaag gtgcagacta
     9181 tgaaaattag taaattacca gaagcagaat taaaagttat aagatatatt taggaatcag
     9241 acaaggtatt aacatcaaga gagattgttg aaactatgga gcaggatgat aagaaagtag
     9301 attaaaaaaa ttaaatgaat tagaagcata ttttaagagt ttgggacaat atgattaata
     9361 aaaaatatag tactatttag taaaaaatgg agtatcaatt ttttgccacc tatggcaaca
     9421 atgaaaaaga tatgtttagc gttagactgt aacatagagg atattgttga gattaaaaaa
     9481 gatgaagatt aataagtaaa aggtagctac tagtataagt gctacctttt tttgtgggta
     9541 atattgtgga taagttgtgg gaaacttata taaaaattgt ggataaaata ttttactgac
     9601 ataaatattg gactttgatt tttaaatgtt gaaatatcaa tgaaaaaata cataaaatca
     9661 taaaagatat tattttaatt agcaatagat tcctttttca aagaagtctt tgatttcatc
     9721 aaggttatta gtttttccaa gtgctaagat aagttttatt ctagcttttt gacctggaag
     9781 gtctccacca aatatacagc caagattttt taaatctcta ccagaaccaa agtaaccata
     9841 actatcgaat actctacctg aatgacacct agaaactata acaacaggaa gccctttttc
     9901 tctagcatat tcaactccag aaagcatttg aggaggaata ttacctctac ccattgcctc
     9961 aataactata cctttatagc cactgtcaac agcaaatctt ataaagtcag cattttctcc
    10021 tacatatgct ttaaataaag caaccttaga ttctacctta tcagtatcta taattgttct
    10081 atttacaata tctcttgtaa ggacaagttc attgcaatca attattccca atggaccact
    10141 agttagagat ttaaatgtat ttagagaaag agtatttgtt ttagtagctt cagaagctaa
    10201 tagtacttca ttgtttaaaa ctacaaggac tccttttccc atagcatctt tggatactgc
    10261 agtacaaact gatgcagata aattacttga accatcatat ccaagttcag aactacttct
    10321 catagcacct gtgactatta caggtttgat gttatcaatt gtaaggtcta gaaaataagc
    10381 tgtttcctct aaactatctg taccatgcgt tattacaaca cctgtaatat cttttcttgc
    10441 taataaatca tttacataat ttttcaattc catcattcta taaggtgtta tatgaggtcc
    10501 tggaatttca tcaaagttaa aaacttcaac gtctgcaact ttatcaatgt tggtaaccat
    10561 tgataatatt tgttcccctg ataaagttgg tatagcagct ccgactttat cgtctactgt
    10621 catagatata gttccaccag taaaaactat ggcaactttt ttcttaatac tcatactatt
    10681 ctctgccttt cataaataaa atttataatt ccgataggat tatatcaaaa aaagtagtta
    10741 aggtctacat aaattctttt attcatataa tttagatatt tcagtgtaat ataattattt
    10801 cttaattttt tgccattcaa caatataacc atttagtatt tctcttatgg cttttcctat
    10861 cttagtataa gcttcatcat atagatttgc tagagatatt ctaattgacc attcaggacc
    10921 atagaatcca tttccactaa gtaaaactac tgaatagtca ttagctaatt tataaagtac
    10981 atctactgga gatgcatttt tacttataaa tttaaataag tcttctccat agtttaattt
    11041 agcccattct tcaatatcaa attgagtgta atatgcagca ttatttttat tttcattaat
    11101 tggaagctct aaagcttcaa ataatagttt ttgacgtcta tggcagatac tcatattaag
    11161 tttcttgtag gcatctactt tatcaatcaa tgcaaaagca gagaaaaatg ccatttgtac
    11221 ttgttgtgga gtagaaagac cagcagtatg gttaagagca acaagtctac tatcagcaac
    11281 aactctttcc ataaatgaaa gactagaagg gttaagactc atatcactgt aacgtttatc
    11341 tactgatttt tttagttccc cagttaaatc atttattttc ttatcaaaaa catttttctt
    11401 gtgaagagca aacgtaccaa gcctccatcc tgtaactcca aagtattttg aataagaata
    11461 aactccaaca gtgttgtaag gtagctttga catcaacgac gaaaaatcct ctacaaaagt
    11521 tccatataca tcatctgata ttatcatcaa atctttatta taattttcaa ttacatctat
    11581 tagattatta caagatgttt catccatagc tatagaagca ggattattag gattaacaac
    11641 gaataaagct ttaatggact tgtcacgaag tttctctaat tctttttttg tatactgcca
    11701 tgtgtgagca cctttttcgt caacttcatt agcatttata tttacaactt taaagtcata
    11761 acgaggaagg ttaggtattt caagataagg tgtaaatatt ggagtcatta aggctatggt
    11821 atctcctttt tttagaagtt catttgccat taatgaatca aaaatatagc acatagcagc
    11881 tgtagcacct tcaacagcaa aaatttctac atcaccatat ttacctgata tatcatattt
    11941 catttcttga actaggtaat cgtgtactat tttttccata tgaggtaaca ttctatctgg
    12001 aagtggatag ttatcaccaa taattccatc agctagttca tgaataaact catctccatc
    12061 aaatccaagt tcatttatac caaagtttat aatatctcta gctaaatatg ctccaggcat
    12121 atctatattt tcatttataa atttaaaaaa tctttcttta ataccctttt tttgaggcat
    12181 tccagctaaa tgacctaaat cccaattaga acgagtttca ttaatggcga aatgaccaaa
    12241 agtaaaaaag gcttctctgg cagttgaaca agtccagttt ggatttccac gacctgcatc
    12301 aagtaattcc ctgttatttt cctttgcagt atattttgca atatctatta atttgtcctt
    12361 aaattcaaaa gggcttattt ttccatatat gtttttgatt tctttataag tatgattttt
    12421 catgttaaat tcctccttat gtaataagtt tcacattttt ataataaaat aaacaagtta
    12481 caaaaatgat tatactttaa ttataatagg tttatagaaa a
//
LOCUS       DAMKOJ010000094        12176 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.102, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000094 DAMKOJ010000000
VERSION     DAMKOJ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12176
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.102"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            52..780
                     /locus_tag="PC592_003015"
                     /pseudo
     CDS             52..780
                     /locus_tag="PC592_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            908..2173
                     /gene="gluD"
                     /locus_tag="PC592_003016"
     CDS             908..2173
                     /gene="gluD"
                     /locus_tag="PC592_003016"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HDF4056957.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            2674..3813
                     /locus_tag="PC592_003017"
     CDS             2674..3813
                     /locus_tag="PC592_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF4056958.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKDININNINLEGFNNISTVISSILLYTWITSVVIY
                     LIYTIFKYIKLKNLISDLSYEVDDEEIINLYRSILKEFDITKDIKLKYSYEVETPAFF
                     NSCVLLPPHDYKLKELDWIFRHELMHFKSKDLYLKYVILFLKIVYWFNPFVYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTIINAMRKGTNTSNKFIAGLHKQSDIKKRVKN
                     MFNEKYKNGILMALTLCLLSSITFLKVNTTSVINFNVLPKGLEDAHVIGSITVTTIEF
                     TYADAPKNVREEHKRNCEELGVIPKDSDQIGVGVEYYNSLSKRSR"
     gene            4272..5294
                     /locus_tag="PC592_003018"
     CDS             4272..5294
                     /locus_tag="PC592_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF4056959.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEENGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQINPSVNQNVDSTNTNQQNNANTSQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVRVTSINSAYYTARFV
                     TAKRIL"
     gene            5589..6509
                     /gene="pyrB"
                     /locus_tag="PC592_003019"
     CDS             5589..6509
                     /gene="pyrB"
                     /locus_tag="PC592_003019"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDF4056960.1"
                     /translation="MLESRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMKIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLENHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDG
                     DDRAVYFKQAKYGMYVRMALIIKLLGISED"
     gene            6548..7240
                     /locus_tag="PC592_003020"
     CDS             6548..7240
                     /locus_tag="PC592_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDF4056961.1"
                     /translation="MYKILENIYIGEDMYRMKVKGTFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEEEYKQVCNEVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNEGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            7233..8135
                     /locus_tag="PC592_003021"
     CDS             7233..8135
                     /locus_tag="PC592_003021"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF4056962.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDNELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVEMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            8220..8804
                     /locus_tag="PC592_003022"
     CDS             8220..8804
                     /locus_tag="PC592_003022"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDF4056963.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            9021..9947
                     /locus_tag="PC592_003023"
     CDS             9021..9947
                     /locus_tag="PC592_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HDF4056964.1"
                     /translation="MKNQLNKSQKKVVFFGVGAVGATFAEQFLNSKYDFKILCNKERK
                     KRYLEDGFIINGKRYDFDYVTRDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYVLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKGISLTEDDVENSLHRILEHSKEGRTSMLQDVEAHRPTEVDMF
                     SKNICKLGKKYSIPTPINQTFFYMIKVIESRF"
     gene            complement(9998..10888)
                     /locus_tag="PC592_003024"
     CDS             complement(9998..10888)
                     /locus_tag="PC592_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF4056965.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSQKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQDQKWIVREDGSGTRDYLDMFLSVKEIIPRSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            11076..12107
                     /locus_tag="PC592_003025"
     CDS             11076..12107
                     /locus_tag="PC592_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDF4056966.1"
                     /translation="MLKKKSILTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKILRVIFLVVVVLVFGHMKNQSNKEILEEEKDEIKKKKVTIPWYVIGFFVTCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFIGIVQVVS
                     AVVLIKIFI"
BASE COUNT         4807 a         1276 c         2181 g         3912 t
ORIGIN      
        1 gcaaaattct atgaagcagg aaccctgtga ctttagtcat gggaggttca ggatggaatt
       61 ttaatataca aaaacaaggt tttagctgga gtatcagcaa aacaagcaaa tactactata
      121 gaagcagtta aaagggctat tttttataat ctggagcata gacaagaagt tagagaaatg
      181 attaaaaaag aaaatataag aaaaattctt attattggaa catcaaaaaa gatggttaat
      241 caaattgtag atagattgtc aattggaagg gtttgtaagt ttataaatat agaagatata
      301 agtactaaat atgaaataga agtagcaaaa caatctagaa aagaaggaaa tcatgtaatt
      361 cctgttccag cagttgagat aaaaagtatg gcaagtggtc ttagtataaa ttctttgaag
      421 agacttttta ggaaaggaaa taataggaat atggtagttt tagaaaaaac aattataaga
      481 ccaaccttta gttatatagg aaagttttat attagtgctg atgtaattaa acagattatt
      541 gaatatgaag tatacagctt tggtagcatt gatagaataa ataaaatcaa tatagagaat
      601 tgcaataatt ttatgaatat ttttgtaagt ataaatatca atgatttaga aactataaaa
      661 aaaattgaag atatacagca gataataaaa aagtctattg agaaaatgac tttagttaat
      721 gtacaaaaaa tagatattaa cattcataaa attaaaaaaa taaacttcct ccaatgttaa
      781 aaaataaact gagaaaatga tatactaatt tgcaataaag tgtgctataa ttaaactgta
      841 aatttaggaa atggtttttc taaatggagt atacataatt ataacgtatt tataaggggg
      901 ctttcaaatg tcaggaaaag atgtaaatgt cttcgagatg gcgcaatctc aagtaaaaaa
      961 tgcatgtgat aaattaggta tggaaccagc agtttatgaa ttattaaaag aacctatgag
     1021 agttatagag gtttcaattc cagtaaaaat ggatgatggt tctataaaaa cttttaaagg
     1081 atttagatca caacataatg atgcagtagg gccaacaaaa ggtggaataa gattccatca
     1141 aaatgtttca agagacgaag taaaagcttt atctatatgg atgactttca aatgttctgt
     1201 aacaggtata ccatatggtg gaggtaaagg tggaataata gtagatccat caactttatc
     1261 tcaaggtgaa ttagaaagat taagtagagg atatatagat ggaatatata aattaatagg
     1321 tgagaaagtt gacgttcctg caccagacgt aaatactaat ggacaaataa tgtcttggat
     1381 ggttgatgag tacaataaat taactggaca aagttctata ggtgttataa ctggtaagcc
     1441 agttgaattt ggtggttctt taggaagaac agctgctact ggatttgggg ttgctgttac
     1501 tgcaagagaa gctgctgcta aattaggaat agatatgaaa aaagctaaaa tagctgttca
     1561 aggtatagga aacgttggtt cttatacagt tcttaactgt gaaaaacttg gtggtactgt
     1621 tgtagctatg gctgaatggt gcaaatcaga aggttcttat gctatataca atgaaaatgg
     1681 tttagatggt caagctatgt tagattatat gaaagaacat ggtaacctat taaacttccc
     1741 aggagctaag agaatatctt tagaagagtt ctgggcttca gatgttgata tagtaatacc
     1801 agctgcatta gaaaactcta taactaaaga agttgctgaa tctataaaag ctaaattagt
     1861 ttgtgaggct gctaatggac caactactcc agaggctgat gaagtatttg ctgaaagagg
     1921 aatcgttctt actccagata tattaactaa tgctggtgga gttacagttt cttacttcga
     1981 gtgggtacaa aacttatatg gatactactg gtcagaagaa gaagtagagc aaaaagaaga
     2041 aatagctatg gttaaagcat ttgaatctat ttggaaaatc aaagaagagt acaatgttac
     2101 aatgagagaa gctgcttaca tgcattcaat taagaaagtt gctgaagcta tgaaattaag
     2161 aggatggtac taggatttac tcttaataaa taataggata taattattta agatataaag
     2221 gggctgtaca tagtacagcc cttaaattat gtggctcagg taatgtgagc cattttttat
     2281 tttaatttat aaattatata actcaaaatt taaaacgcta taagtaagac gagtgataat
     2341 ttatggttaa tttaatttta agtaggcttt ttagaactat tctagtgaat agtttatgta
     2401 ttcttttaat attagcattt aagaaaagta tttttgttct attttaactt tgcttttata
     2461 tatttataac tgtcaaagtt atatggagtt aaattaattg atgatgttta atgcacagta
     2521 atcattacta agctataatt aactataaga taataaaaca tagttattta ttacagaaaa
     2581 tatatatttt aattaataaa tatgatatga aagtgttaag agataactaa aattaactat
     2641 aaaacactat taaataagat aggggaaaaa catatgtcta attttattct aaatgggatt
     2701 tttagaactg ttatagtgag tagtttaagt attcttatga tattaatatt caagaaaaat
     2761 gtgtttaaaa gatttagtaa aaaatttaac tattatatat ggatgatagt tgttattaaa
     2821 ttatttctac catttacata ttatactttt acaataaata tattaagaag caaaaaagac
     2881 attaatatta ataacataaa cttagaggga tttaataata tctcaactgt aattagtagt
     2941 attttactgt acacttggat tacatctgta gtaatatatt taatttatac tatattcaaa
     3001 tatataaaac ttaaaaattt aataagtgat ttatcttatg aagttgatga tgaagaaata
     3061 ataaatcttt atagaagtat attaaaagaa tttgatataa caaaagatat aaaactaaaa
     3121 tactcatatg aagttgaaac accagcattt tttaattcat gtgtgctttt gcctccacat
     3181 gattataaat tgaaagaatt agattggatt tttaggcatg agctaatgca ttttaagagc
     3241 aaagatcttt atttaaaata tgtaatttta tttttaaaaa tagtatattg gtttaatcca
     3301 tttgtatata taatggataa acatatagat ttagattgtg agctttattg tgatgaacgc
     3361 gttttaaaaa atagaaactc agaggaaaaa aaagattacg ctttgacgat tataaatgcc
     3421 atgagaaaag gaacaaatac ttcaaataaa tttatagctg gtctacataa gcaatctgat
     3481 attaaaaaga gagtaaagaa tatgtttaat gaaaaatata agaatggtat attgatggca
     3541 ttaaccttat gtctgttatc ttctattact tttttgaaag ttaatacaac tagtgttatt
     3601 aattttaatg tattacctaa aggcttggaa gatgcacatg ttattggtag tataactgtt
     3661 acgacgatag aatttacata tgcagatgct cctaaaaatg tgagagaaga acataaaaga
     3721 aattgtgaag aactaggagt gattcctaaa gactctgacc aaataggtgt tggtgtagag
     3781 tattataaca gtttatcaaa acgatcaaga tagtaatatt ttaatagatt gtaatttata
     3841 atagttataa agttttaaac agttatttat taagaaaaaa tatattttta taaatgtata
     3901 tacaaaatca caaaatgact aactttatag ttattccctc aaaaaacata tgccacatag
     3961 aaacgcataa aaaaacacat aaaacaatat ttatgcgtac tttagcctct aaaggtacaa
     4021 aattctttac ttttacagac tcgtattata taattaagta aataatgtat atttaggtga
     4081 catattggat aaactaattt atttatttta ttaatattat aatactataa aagttatata
     4141 aagtggttta caaaaaagtt acagatagag cttttattaa tgtattgtgt attagtattt
     4201 tatccttagg tacacttcac ctacaaaata gaatcataag ataattatgg gaaaatttta
     4261 ggaggtttat cgtgaagaaa aagatattaa taccagtatt tgcatcagtt atggcattat
     4321 cagtaagttc aattgtaaat gcagatgaag taaatgattc atctcaaaat aaggatgata
     4381 aaacaaatac tgaattaaat ttaggtgaat ataaagaagt aaaatataaa gttgcaaaaa
     4441 taaaagatgg agtagctata aagataagag aagaaggtca agttcaaaat atagcttatt
     4501 ctggagatga gtttactgtt ctaggaactc aaggagaatg ggttaaggtt aaagttgaag
     4561 atggcgaagg ttggttagct actagatatg tagatatatc tgaaggtgta ggatatacta
     4621 acgctgataa agtaaattta agaaaagata agagtgaaag ttcagaagta attgaagagc
     4681 tagaaaaagg aagctcttta ttggtcttgg aagaaaatgg agattggtta aaagttaaag
     4741 atggggaaac cgaaggatat gtaaaatcat cttatatatc tgataaagct cctgtaatag
     4801 aagagccaca aataaaccca agtgttaatc aaaatgtaga ttctacaaat actaatcaac
     4861 aaaacaatgc aaatactagt caacaaaaca ataattcaaa tgtgccaaca gctaactcta
     4921 atgcagttca agctgtactt aatttggcat attctaagca aggttgccca tatgtttggg
     4981 gagcagaagg accaaacact tttgactgtt ctggatttac acaatatgtg tatagaaatg
     5041 cagtaggaaa gaatatacca agaacatcta aagcacagtc taaatatgga caaactgtaa
     5101 gtaaagcaaa tttacaacca ggagacttag tattcttcac aactaatggt tctggttctg
     5161 ttagtcatgt tggaatatat gtaggtgggg gtaatatgat acattcacca tcaacaggaa
     5221 aaacagttcg tgtaactagt ataaattcag catactatac agcaagattt gttacagcaa
     5281 aaagaatatt ataatcagtt tgtaatatga caaattgata aatacataaa tatatataaa
     5341 cgctctatat tatatttaat ttaatcatgg aaataaaaaa tgattatatt ttaaatgtac
     5401 tatagagcgt ttttgtatca ctttaaatct aatcaggatt cagggtgata ttactttaaa
     5461 taggagcatt ttcatatgat gattatttgc gcaatccctt gacaggatag ggcaaaggtg
     5521 gtaagctact aacagtacaa aaatactttt aattttagtt cagagaggct aaaaaaggag
     5581 gacgaaagat gttagaatca agaaatttaa tccaaccaga agacttttca atagaagaaa
     5641 tagatgaaat attagagtta gctcaaaaga taattgacaa tccgtcaaaa tattctcgta
     5701 tatgtgaagg aaaactatta gctacattat tttatgaacc atcaacaaga actagattaa
     5761 gctttgaatc tgctatgaac agactaggag gtcgtgtagt aggcttttca gagccaaatt
     5821 catcttctgc atcaaaaggt gaaaccctag gtgatacaat gaagatagta tctggttatg
     5881 ttgatataat agctatgaga catcctcaat caggtgcagc atcagaagca gctagatata
     5941 cagaagtgcc atttataaat gcaggagatg gcaaaaatca gcatccaact caaacactta
     6001 cagacttact tactataaaa tcattaaaag gaactttaga aaaccataca ataggattat
     6061 gtggtgattt aaaatatgga agaactgtgc attctttggt taaggctatg gcaagatata
     6121 aaaatacaaa gtttgtattt atagcaccag aagagttaaa aatgccagat tatataaaag
     6181 aagctataaa gggacatgca tattatgaaa ctaataattt ggatgatgtt ataggaagct
     6241 tggatgtttt atatatgact agagttcaac aagaaagatt tgaagataaa tcagaatatg
     6301 aaagacttaa aaactattat attttaaata aagccaaatt agaaaaagca tctaaagata
     6361 tgttagtaat gcatccatta ccaagagtaa atgaaataga catagacgta gatggtgatg
     6421 atagagctgt atattttaaa caagctaaat atggaatgta tgttagaatg gctttaataa
     6481 taaaactttt aggtataagt gaagactaat agttatcata taatagtaaa ataaaggaga
     6541 ttttgggatg tataaaattc tggaaaatat atatataggc gaagatatgt atagaatgaa
     6601 agtaaaaggg acttttgaag gtaaaatggg acaattctat atgctaaggg catgggacac
     6661 ttatccagta ctttcaagac ctataagtat acatgatata gatgaagaag ggataacttt
     6721 tctttataaa gtagtaggag aaggaactca aattttgagt aacctaaaag taaatgatac
     6781 tataaaatta gaaggccctt atggtaatgg atatgctaag gttgatggaa aggtagctct
     6841 agtaggagga ggaatcggtg tagctccact atatttggtt gctaaaaata taaaaaattg
     6901 tgacgcatat ctagggttta gagaagatgt tatattagaa gaggaatata agcaagtatg
     6961 taacgaagtc tatacaacag taggaaatac ttttgtaaca gatataattg atgtggagaa
     7021 atatgattat atattaacat gtggtccaac tccaatgatg gaaaaattag ttaagatggt
     7081 agaaggtact aaaacgagaa ttatggtatc tcttgaaaat catatggctt gtggagtagg
     7141 tgcttgttta gtgtgtacat gtaaaactaa tgaaggaaat aaaaagactt gtaaagatgg
     7201 tccagtgttc tggggagagg acgtgatttt taatgggtaa tttaagtgtg aaatttggaa
     7261 gtgtagaatt taaaaatcca gtaataatgg cgtctggaac ttttggattt ggaaaagaat
     7321 ataatgaaat ttatgatata caaaaacttg gtggtataag tagcaaaggt cttactttaa
     7381 ataaaaaacc tggtaacaat ggtatgagag ttcatgagac accgtctggt atgatgaata
     7441 gtgttggtct tgaaaaccct ggagttcaag gttttataga caatgaatta ccatttttca
     7501 gtaaactaga tttagtaaga atagctaatg ttggaggtgg gacattagaa gactacttat
     7561 taggggttca aatgttaaat gataaaccta tagacattat tgaattaaat atatcttgcc
     7621 caaatgtcaa agctggtgga atggcttttg gtataaaaaa tgaagtggca agagaagttg
     7681 ttcgtgaggt aagaaacata acgaaactgc ctttagtaat aaaattatca ccaaatgcag
     7741 aagacattgt agaaatggca aaagtttgtg aagaagaagg tgctgatgga gtttcgttag
     7801 ttaatacatt taaagcaatg gcaattgata taaaaaatag aagaccagta tttgaaaatg
     7861 tatatgctgg gttatctgga ccagctataa aacctatagc tttaagaatg gtacatgaag
     7921 tgtgtaaaaa tgtaaatata cctgtaatgg gaatgggcgg aataactaaa gcaacagatg
     7981 ctatagaatt tataatggca ggagccactt gtattcaagt tggaactgca aactttatga
     8041 atcctagaat cggtattgaa ataatagatg gaattaatga atttatggat agagaaggaa
     8101 taaaaagttt agacgaaata agaggaatta tataaggtag aataaatagt attttaaaga
     8161 taaaaaatat agattaaata aacaataatt ttataacatt aacatggagg aaaaataata
     8221 tgagtaaagt agatgtagta gatatattaa agaaaagtga tgcattgttg gagggacatt
     8281 ttttattatc ttcaggaaaa cacagtaata gatatgtaca atgtgcaaaa gtattaagat
     8341 tcccagaata tgctgctgag gtattaagta cagttgttga acaaataaaa gacttagata
     8401 tagacttagt agtagggcca gctatgggtg gagtaatagt ttcttatgaa ttgggaagac
     8461 aattaggaaa agaagctgta tttactgaga gaaaagacaa tacaatggag ttaagaagag
     8521 ggtttgaagt taaaaaagga gcaaagataa taattgctga agatgttgta actactggta
     8581 aatcaactat ggagacaaag agagtattag aagccttagg tggagaagtt gtaggtgttg
     8641 catgtatagc agatagaact aatcatgata taggtatgcc tatatatagt gctataaaac
     8701 ttgatattca agtttatgaa tctgatgagt gtcctttatg taaggaagga aaattaccag
     8761 ttgttaagcc tggaagtaga gagttcaagg aattaggaat gtaataaaaa cttaattatt
     8821 tatagtagta ttaaaaaaaa gtgaattttt cagaataaaa atttggaata taaaatataa
     8881 attaaaaata aagagcagtt agccttataa atgaaggtta gctgtttttt tgttaaaaat
     8941 atatttacaa aataagagat agtagcagta caatataagt ataaaataaa aaccattgta
     9001 tgcattaggg aggggtaagt atgaaaaatc aattaaataa aagtcagaaa aaggttgtat
     9061 tttttggagt aggagctgta ggagctactt ttgcagaaca atttttaaac tctaaatacg
     9121 attttaagat tctttgtaat aaggaaagaa aaaaacgata tttagaagat ggatttataa
     9181 taaatggaaa aaggtatgat tttgattatg taactagaga tgaatataaa caagaagctg
     9241 actttataat tataggttta aaatataata atttgaaaga aaatataaaa gaattagatg
     9301 gattagttgg aaaaaataca gtcataatgt ctctgctaaa tggagttgat agcgaagaga
     9361 taataggtga aagatttgga attgaaaaaa tggtatattc atatgttacc aatatagatg
     9421 caaagaaaat caataataat attatacaca ctactaatgg gataattgta tttggtaaca
     9481 aagataacag tgaagataga aaaactaata taataactga ggtttttgat gatgtaaata
     9541 tagaatatgt tttatcaaaa gatattcaac gagatatgtg gtggaagtac atggttaata
     9601 ttggtgtaaa tcaaacttca gctatacttg gtgcacctta tggagttttt cagagttctg
     9661 aacatttaag agaattagca aaatctgcaa tgagggaagt tgttgctata gcccaagcaa
     9721 aaggtatatc tcttacagaa gatgatgtgg aaaattcatt acatagaata ctagaacatt
     9781 caaaagaagg aagaacatca atgcttcaag atgtagaagc tcatagacct acagaagtag
     9841 atatgttttc taagaatatt tgcaaacttg ggaaaaaata tagcatacct actcctataa
     9901 atcagacctt tttttacatg ataaaagtaa ttgaaagtag attttaaggg tttttgtaag
     9961 aaactttgat aattattgat tttaaatttt attaatgtta tatactattt aagttactaa
    10021 atatttttaa ctcttcaatg aaaatagttg ctgcttttga taaagttata tcttttggaa
    10081 atatatatga gaaatgtctg ttgtagctgc ttccaagctc tatgacagac aactcattgt
    10141 ttaaaacagg taagcttgtc actagattag agactattgt aattcctaaa ttatttctaa
    10201 cagattcttt gacagcataa ttacttccaa aaaccatcat actccttgga ataatttctt
    10261 taacacttaa gaacatatct aaataatctc tagttccaga cccatcttct ctgactatcc
    10321 atttttggtc ttgaagttta tcaaaactaa aatcttttaa caaatgactt ttgtatggaa
    10381 gtgctagaac catcttatct tcaaaaaaat attcttgaat aaatgaaggg gaagagcaag
    10441 taccttcaat aagaccaatg tctaaaatat aatccttaac atgagaagat acgattgacg
    10501 tattttttat aaaaacttct acatctatgt caggatactt ttgagaaaat aacgctagaa
    10561 aatttggtag aatatactct ccaatagtta aacttgcgcc aatctttaag tgaccagtta
    10621 tagcatctga aacttggctt acatcatgat aagtaatatt taaaagattt aatatttctt
    10681 tagctctttt atacaatatt tgtccacttt ctgttataaa aatggttttt tgtttaatag
    10741 acctgtttat aagcacaact ttaaaataat tttctaaatt ttttatgtgt ttacttacac
    10801 ttggctgtga taggtttaag tattccccag ctttagtaaa atttttgtat tcaacaacag
    10861 ctacaaatgt ttttaattct tcaaacaatt ttttgtctcc tttacctaat taaattttac
    10921 attttttata tactttctac agataattat actatatata ataaccatta aaaacattaa
    10981 tcattacgat attatatatt tattttactt atggttatta caattatata ctattgctat
    11041 gaagaaaact atattaatta taaggtaggt atattatgtt aaagaaaaaa agcattttga
    11101 cattaaaaac tataagggaa atattaccag ggttgtttgt atcagtatta gtaggttata
    11161 ttagtatatt tatttctatt ttaattccta aggtaggagc agcatcaatt tctatatttt
    11221 taggtatgtt tgtaggaaac ctatttttaa atcaaaaagt gtttcaaaaa ggttataaat
    11281 tttcagagac agatttgtta tcatattcaa tagtactatt aggagcaaca ctcagtgtat
    11341 ctaccttaat agacttaaaa gtttcaggaa ttttatttat aatattgcaa atgacaataa
    11401 caataatagc tgcactttat ataggtaaaa aactaggatt tgaagaaaac tttagatttc
    11461 taatggcaag tggaaatgca gtatgtggtt cttctgctat aggagcaaca gttccagtgg
    11521 ttaatgcgac agataaagaa aagggaattg cagtaactat tgtaaatgtt actggtatat
    11581 tccttatgtt tttacttcca ataatatctc aatttttata tagccatgaa cttgtaaaaa
    11641 cgtcagcaat gataggtggg actttgcaat caattggtca ggttgtagca agtggagcaa
    11701 ttgttggaga aaatgtaaaa gatttggcta ctatttttaa gatattaaga gtaatatttc
    11761 tagttgttgt tgtattagta tttggacata tgaaaaatca gtctaataag gaaatccttg
    11821 aagaagaaaa ggatgagatc aaaaagaaaa aagtaactat accatggtat gtaattggat
    11881 tctttgtaac ttgtgcactt ttttcaatga acattatacc aaaagaagta tctgtgttgt
    11941 gcaaagaaat aagtaacaaa ctagaaataa tagctttagc agcaattggt ttaaaggtta
    12001 atgtaaaaga tttagtgaaa caaggaaaag aagtttcttt atatggttta tttataggta
    12061 tagtacaagt tgtatcagct gtagttttaa taaaaatatt tatatagcac aaaaatagta
    12121 tttgtaatat caatttcatt aattaaaata atatgatact aataatttat aatata
//
LOCUS       DAMKOJ010000095        11932 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000095 DAMKOJ010000000
VERSION     DAMKOJ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11932
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.103"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(210..362)
                     /locus_tag="PC592_003026"
     CDS             complement(210..362)
                     /locus_tag="PC592_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDF4056967.1"
                     /translation="MATFIIAAIVVVLMALAVMYMIKNLKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(388..2544)
                     /gene="feoB"
                     /locus_tag="PC592_003027"
     CDS             complement(388..2544)
                     /gene="feoB"
                     /locus_tag="PC592_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF4056968.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKEAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISNIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKVPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSIKGVLIHM
                     WDRGKAFIVKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVANAFAFMAF
                     NMLCAPCFAAIGSIKREMGSWKWTWITLGFQTLTAYIVALLINQVGSLVLGTGGSIAG
                     AIISVVIAVGVVFAVLTYSNRNMKKEKMGKLSYMKN"
     gene            complement(2647..2868)
                     /locus_tag="PC592_003028"
     CDS             complement(2647..2868)
                     /locus_tag="PC592_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF4056969.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEITVRDYELSIRKSDAEKIIVE"
     gene            complement(2881..3093)
                     /locus_tag="PC592_003029"
     CDS             complement(2881..3093)
                     /locus_tag="PC592_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF4056970.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(3414..6311)
                     /locus_tag="PC592_003030"
     CDS             complement(3414..6311)
                     /locus_tag="PC592_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4056971.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIKVGYCD
                     DYGIISSSKEHSYSGYGYDYLREISKYTRWEYEFIKGSWEECLDRLEKGEIDLLGPLQ
                     KDDERNKIFNFPKLSSGYEYSALYTDDSNNNMFYEDINSFNGMRVAVLRGNFHNIAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIIDAKGMKIVSKFSVEPFYFA
                     TAKDKPNLAKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEINFIKANPK
                     LTMVYDSEWSPVEYYDKKSNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMICGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYNSVESCLNAINEGKANLMVLSSYQFDELLRKGKSENLSVISVL
                     DTSYGMRIGVSNKTNPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLKRIAYTDSLTGVDSINKFKINSNKLFAK
                     NNPEEYALFYMDVDKFKYINDMFGYDMGNNTLIHISDTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNSIYNKVQIFSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFVVYFQPKYRLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQE
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTSLIELELTETAVLDNIEGLLDTMNN
                     LKENGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(6637..7245)
                     /locus_tag="PC592_003031"
     CDS             complement(6637..7245)
                     /locus_tag="PC592_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDF4056972.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFIAGYSVGA
                     TIAWRCSEDSLCDGIICCYGSRIRDYMDVIPKCPTLLVFAKYDSFDVNSISCQLSRKQ
                     NIQIEILDANHGFIDIYSKNYSDIQTKAFTVKEKSFLSKCLV"
     gene            complement(7505..8050)
                     /locus_tag="PC592_003032"
     CDS             complement(7505..8050)
                     /locus_tag="PC592_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF4056973.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(8168..9991)
                     /locus_tag="PC592_003033"
     CDS             complement(8168..9991)
                     /locus_tag="PC592_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056974.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKSLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPTVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYEIKSVNDFKEINDRLLKISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGVLASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEKEEQELDNMFKSELKDNKDGNSNSHFVKGEIELKNVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDSKDIYSIDRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANSHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(10004..11779)
                     /locus_tag="PC592_003034"
     CDS             complement(10004..11779)
                     /locus_tag="PC592_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4056975.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGVIMIGITFLGAIFAIIRSVISARVSQHFSYYLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKVGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENKSF
                     EELNYELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRYLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLIDEDEEVIERDKSSDIGEKDLKFA
                     NCDIIFENVDFAYNKNTGEKILKNISFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGHSIYSISEESLRERIGVVFQNSSVFGKSILENVVMGNRNIRKEDVIKSC
                     EIANANQFITKLENSYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKDHISNLRENEGKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFTLQNLVSEDVN"
BASE COUNT         3984 a         2149 c         1084 g         4715 t
ORIGIN      
        1 gtagctattt tttaatcaaa tttaaacata atatttactc atattgctta atttagcaat
       61 aatccctcct aatcatatat ttatttataa ttatacagta aaattacaac atagtctaac
      121 ttacttcaaa tatgaaattt gttatttata taaaaaataa gaacctgata ataaagtaat
      181 ctaaactttt tatcaggctc ttatcctatt tatctcttag cactatggca actcttacta
      241 cttgagcatc cagaacaacc acatccacaa ctgctaccat tcttttttaa atttttaatc
      301 atatacatta cagccaatgc cattaatact actacaatag ctgctattat aaatgtagcc
      361 atatttatca ctccttattt atatgaatta atttttcata taacttaatt tacccatttt
      421 ttcttttttc atatttctat ttgaataagt taaaactgca aataccactc ctactgctat
      481 aactacagat attattgccc cagcaatact tcctccagta cctaaaacta aacttccaac
      541 ttgattgata agaagagcaa ctatatatgc tgttaaagtc tgaaatccta atgtaatcca
      601 tgtccacttc catgaaccca tttctctttt tatagaccca atagctgcaa aacaaggtgc
      661 acaaagcata ttaaacgcca taaatgcaaa cgcattagct actgtaaaca tacttgcaac
      721 tgaagcaaga agtgttgggt cttgctctgt tgcatctgat attccaaata aaacaccaaa
      781 tgttccaact acattttctt tagctactag acctgtaact gttgctactg atgattgcca
      841 atttccaaat ccaagaggcg caaatattgg tgcaactata tttcctaagc tagctaatat
      901 actatctcca gcatctacca tttgtaatga ccaattaaat gattgtaaga accaaatcac
      961 tccacaagca acaaatataa ttgttcctgc tttgactata aatgcttttc ctctatccca
     1021 catatgtatt aaaacacctt ttatacttgg aatatgatat tgaggtaatt ccataacaaa
     1081 tggagatggt tctcctgcaa ataaactagt tttctttaat ataattccac aaatgattat
     1141 cattgcaata cctaagaaat acattgatgg agctacccat gaagcacctc caaataatgc
     1201 ccctgcaaat aatgctatta ttggaacctt agctccacat ggaatgaatg tagttaacat
     1261 aatagtcatt tttctatctc tatcattctc tatagtacga gttgacataa ctcctggaac
     1321 tccacaacct gaacttataa gcattggtat aaatgatttt cctgaaagac caaacttacg
     1381 gaaaattcta tccattataa aagctacacg tgacatatac ccacaatctt ctaatattga
     1441 taataataag aataaaagca tgatttgtgg tacaaatcct aatactgctc caactccacc
     1501 aattaaacca tcaactacaa gtccttgcaa ccactctgct acatttaaag aagctagaaa
     1561 attacttaca ttaccttgaa taatttctcc aaacagtaca tcatttgtcc aatcagttgc
     1621 tatagtaccc aatgaactta ctgctatata gtaaactccc cacattataa gtgcaaaaat
     1681 aggtaatgct agtatacgat ttgttacaat cttatctatc ttatctgata cagtttcctt
     1741 accttttcta ttcttcttta ttatatttga aattattgaa ctaataaact cataacgatt
     1801 ggctgttatt atactttcac tatcatcatc caattcatct tcacaatttc tagttatttc
     1861 ttcaatgcta ttcaatattg ttttagaaat atcaagtttt tgtataacat tttcatctct
     1921 ttcaaataac tttatagcta accagcgtgt ttctacatct atatatggag tcttttcttc
     1981 tattattttt tcaatttttt ctattgcttc cttactttca tcaacgaaag gtaatttgaa
     2041 atttaattta ttgttactac ttgcaagttc aactgccttt tcagcagcct ccataattcc
     2101 ttgaccttta actgctgtta cttctaccac tgggcaacct ataacttcag atagttcttt
     2161 aatatttatc ttatcaccat tcttattaac aatatccatc atattaagag ctataacggt
     2221 cggtataccc agctctaaaa cttgagttgt aagatataaa tttctctcta tatttgatgc
     2281 gtctacaata tttattactg catccggctt atcatctaac ataaaattac gtgtaactac
     2341 ttcttctaat gtatatggag ataaagaata aatacctggt aaatctacta tctccacatc
     2401 tttatttcct tttaactttc cacctttttt ttcaactgtt actcctggcc agttcccaac
     2461 atattgtgat gaacctgtaa gaccattgaa cattgttgtt ttaccacagt taggatttcc
     2521 tatgagacct atttttattg acatttccat tccctccatt attatttaag tacataacta
     2581 ttcatgatac agaaaatcat tctcattata taatcgcact aaacctattc taactaatta
     2641 attttattat tccacaataa tcttttctgc atctgattta cgaattgata gttcataatc
     2701 tctgactgtt atctcaattg ggtcaccaag aggagctact tttcttataa atatattaac
     2761 acctcttgta atccccatat ccattatacg tcttcgtgta gctccttcgc cttctaactt
     2821 tttgactttt acagtctctc cacacttaat atcctttagc ctgttcatat tattacctcc
     2881 ctatattatt attctacttg ccattttttt atctaatgca actctagtat cttttacatc
     2941 tattattaag ttaccatcta tcttagaaac tatcttaaca tttgtaccta ctacaaaacc
     3001 tatactattt aaaaaagtcc tcgtcttatc acttcctgaa attttcttta taactacttc
     3061 ttcacctgta tttgataata tcaatggcat catatagtaa ccctcctctt aaactgattt
     3121 aaatccacaa gcaatcatca tctaatatat aaattacaat atcttaaatc ttaatctatt
     3181 aaaataatcc tctatttttt tccttctttt tacaactcct aattttgatt taagtctacc
     3241 acaatagtat gttttttgca agtgattatt gtattctttt gatttttttt ctcatttgat
     3301 tcattatatt aataaaacag taaaaattaa tacaaaaata aagatgctct aaaatagtat
     3361 actcaactat attaaagcac ctttattata tatgtcatta cttaaacatt gctttattct
     3421 tttttaaagg caattttttc aaactctttt acaggcattg gcttagaaaa caaatatcct
     3481 tgtaccatat cacaaccaat ttgctttaga aattctactt gcgaaatagt ctctactccc
     3541 tctgatatta ctttcatttt cagttccttt gccattttaa tgacattaga tataacaatt
     3601 ttttcattat tactctcatc tttttctgta aaaaatgctc tatctagttt taatatatca
     3661 acaggcaact cttttaaaag attaagagag gaatatcctg taccaaaatc gtccatagaa
     3721 attacaaatc cattttcttt caaattgttc attgtatcaa gtaaaccttc tatattatct
     3781 aatactgctg tttctgttag ttctaattct ataaggcttg tcggaatttt gtatttatct
     3841 acaattaact taaacttctc tataaaatta ctatttacaa aatgcattcg ggacaagttt
     3901 acagatatag gtactacttc ttgaccttca tccatccatt ctctaatctt tttacacact
     3961 tcctcaaata catagaaatc aatatttaca ataaaaccat ttctctcaaa tacaggaata
     4021 aattctatag gtggtattag acctttttgt ggattatccc atctaacaag agcctctgct
     4081 cctataatct gataatctga aagcctatat ttaggttgaa aataaacaac aaattctcca
     4141 ttattaagag catctaccat tgagttttca atttctttct cttttaatat ttttttatgc
     4201 atttccttat cgtaaaaagc aaatgaattt ttatgaccac cttttatagt ttttcttgca
     4261 gtattagccc tatccatgat agtgtttata tcattatcac ttttacttat tttatatata
     4321 ccacaatcta aaattaattt ataatagttt attttaggat tactaaatat ttgaacctta
     4381 ttataaatac tgtttaacct tgttttaata tcatcatctg tcttatactt aataagaaga
     4441 acaaaatggt cagcagaaac tcttgcaaaa atttcatctt cctttaattc acttgcaata
     4501 gtatctgata tatgtatcaa agtattattt cccatatcat atccaaacat atcatttata
     4561 tatttaaatt tgtcaacatc catataaaac aacgcatatt cttctggatt attcttagca
     4621 aacagtttat tcgaatttat tttaaattta tttatactgt ctactcctgt caatgaatct
     4681 gtatatgcta tcctctttag atagtcctct ttcttctttt tattataaat tatatattta
     4741 atagcaatta agaataaaat acatacaaaa gaaataattt gtattgaata ttctttaaaa
     4801 atcacaccaa atggtacttt ataaggtttg tcaatagtat tagaatatat gcaatcactt
     4861 aattcttctt cagtaatttt atctattgac ttatttaaaa tagacactaa tataggatta
     4921 gttttatttg atacccctat acgcatccca taacttgtgt ctaaaacaga tataacagat
     4981 aaattctcac tctttccttt tcttaaaagt tcatcaaact gataagaact aagtaccatt
     5041 aaattagctt taccttcatt tatagcgttt aaacaacttt ctacactatt ataagatgtt
     5101 gtcttagcat tttcaaaact cttttctata taagaatcaa tagacttata gctactagtt
     5161 aaagcaatat ttaaatcatt attgagattg gtatccaatt ttcctaccat aatcattgga
     5221 atatttatgt atggatttgt caatttcata ttaaatcgct ttgccttatc attttcattg
     5281 attgaaccac atatcatagt tgcctttcca ctttttatgt aatcaaggct ctcgttataa
     5341 ttttttgttt taatatattc aaattttatg ccacattttt ttgatataat tgacattaaa
     5401 tctgaactta tgcctttaaa tgaattactt ttcttatcat aatactctac aggagaccac
     5461 tctgaatcat acaccatagt aagttttgga tttgctttaa taaaatttat ttcttgtcga
     5521 gtaaatgcta tggaattgtt aacctctctt ttgaaatatt ttttatataa ttccagctca
     5581 taatacatat catttatttt taattctttt aaagcataat ctaattcttt tgccaaatta
     5641 ggtttatctt ttgcagtagc aaaataaaaa ggttctactg aaaatttact aactattttc
     5701 attcctttag catctataat acttccacaa acaaatgcat ctgctttttt ttcattgaca
     5761 gactcaatca attcatcaat agaattacag tatatatatt caactgaaaa attattttct
     5821 tctctatact tctcaaatgc aatattatga aagtttcctc taagtacagc cactctcatt
     5881 ccattaaagg aatttatatc ttcataaaac atattattgt tactatcatc tgtatataat
     5941 gcactatatt catatcctga acttagttta ggaaaattaa atattttatt tctttcatca
     6001 tccttctgta aaggtccaag taaatctatt tcaccttttt ctaatctatc taaacattct
     6061 tcccaagacc cctttataaa ttcatactcc catcttgtat attttgagat ttctcttaga
     6121 taatcataac catatcccga ataagaatgc tcttttgatg aggatattat tccatagtca
     6181 tcacagtatc caacttttat tttttttgaa ttttcagact catcagcaaa gcatagtata
     6241 ttattaaaac atgatataat aagtaaaaat atcaaagaaa gtatcaagaa gtgcttttta
     6301 aatgctttca tatttaaaaa cctccaattt gccaacttac tttaacttat ttggttttct
     6361 agttgtaact acttttattg taatggtaaa tatatcaaat tgcaatattc tcatataata
     6421 ttcttattta actataatga atttatcatt atctatttaa ataccatgtc taataccaat
     6481 ttcttataaa tcataaaagt ataattaaca ccataattct agtgattaat tttatttcaa
     6541 aaaatgtaat aacactacca atattttaaa tatcaatagt gtcaaaaatt ttttcagatt
     6601 aattaaatct ttatatatat tttataataa tccaaatcat actaaacatt tagacagaaa
     6661 acttttttct ttaacagtaa atgcttttgt ttgaatatca gaataattct ttgaatatat
     6721 atctataaaa ccatgatttg catctaaaat ctcaatttgg atattttgtt ttctagaaag
     6781 ttggcaagaa atagaattaa catcaaatga atcgtacttt gcaaatacta acaaagtagg
     6841 acattttgga attacatcca tgtaatctct gatacgagaa ccataacaac agattatgcc
     6901 atcacaaaga gaatcttcac tacatctcca tgcaatagtt gctcccacgc tatacccagc
     6961 aataaataca tatttatact ctgattttaa atcatttata agcttttcaa cttttttata
     7021 aatatcaaaa ccaacattat ttataaaaaa atcatatgcc tcttgaactt ttgaatatgg
     7081 aaaaactctt ttttctccca gaagttcagg acaaaataca tcatatccat atttataata
     7141 cttttgacaa acatcttcta taaagctatt aatcccatag atttcatgca aaacaacaat
     7201 agctacatca cttttatgta tatactttat cagattatcc accaccttta caaaatagca
     7261 aattttttat acttagttta atatattatt ctttacatgt caattcactt ttttaaaacc
     7321 aaatttattt ttggattaat cacttgtttt taaaaattgt gtattattac tcttaaatta
     7381 ttccctattg ttaaaaacat aattgttaga aataaaaaat atagtataaa taataaaaaa
     7441 atatctcact cataacttta aaaattataa gtgagatact cttaaaatct actttatatt
     7501 aaatttattt tccaaaatat ctatttaata atcctaagaa tgctttacca tgtctagctt
     7561 cgtctttaca catttcatgt actgtatcat gtatagcatc taatcctaac tctttagctt
     7621 tcttagctaa ttttaatttt ccatcagttg caccatattc agcatcaact ctaactctta
     7681 agttttcttt tgtatctgca actacaactt ctccaagaag ttctgcaaat ttagcagcat
     7741 gctcagcttc ttcaagagct attctcttat aagcttctcc tacttctgga taaccttctc
     7801 tatcagcttg tctactcatt gctaaataca ttcccacttc tgtacactca ccaacaaagt
     7861 tagctcttaa tccttcgatt atttcttcat ctacaccttg agctactcct attctgtgct
     7921 catcagccca atttttttcg cctttcattt cttcaaattt atcagctcca actttacata
     7981 ctggacattg tgctggtgca gcatctcctt catgtatata tccacatact gtacaaacaa
     8041 atttcttcat aattaatttc ctcctaaatt ttatatatca aattaaattt tttatttatt
     8101 aagttagtct atatataccc gcaccatata cctttaaaca atttttttta aagttttttc
     8161 taagtactta ttttccctgt gtcaatagta tgtttctata ataatgtcct tttaatttta
     8221 tcaattcttt atgatttcca gattctacaa ttctaccatt ttctaaaact attatattat
     8281 cacaatttga tatagtactt aatctatgag ctataattat acttgttttt ccataagtta
     8341 aattatttat tgcctcttga attttagctt ctgttgctat atctatgttg cttgtagctt
     8401 catccaaaat aagtattgga gcatttttta ataccgctct agcaatactt attaattgtt
     8461 tttggccttc acttaaatct tcacccctat ctgataatac agtactatat ccttcacgca
     8521 ttttaactat aaatttatgt gaatttgcta ttttactagc atatataact tcttcatcag
     8581 tagcctccag atttccatac cttatatttt ccataactgt atcattgaat atataacctt
     8641 cttgtgggac tacaccaaaa cacgttctca aatagtttct gtcaatagaa taaatatcct
     8701 tactatctaa aaatatactt ccttcatcta tatgataaaa atttgtaatt agatttataa
     8761 ttgttgtttt tccacttcct gtctctccta taatggcatt tgatgtacca gctttaattt
     8821 ttaggtttat attatctaaa attttctttt ttgaatcata agaaaaactt acatttttaa
     8881 gttcaatttc tccctttaca aaatgagagt ttgaattacc atctttatta tccttaagtt
     8941 cacttttaaa catattatcc aattcttgtt cttctttttc atctataatt tcaaaaactc
     9001 tttcacatcc agctatggct gaaagtaatg tattaaatag atttgccaat tcatttaaag
     9061 gtcttgtaaa ttgtcttaca taacttaaaa aactagctat aacccctatg gttataatat
     9121 ctttagatgc aagaacacct cctataatac atatagttgc aaatcctata ttactaatca
     9181 cattcataat aggcattaaa agagaagtat aaatttgaga tttaagggaa atctttagaa
     9241 gtctatcatt gatttcttta aaatcgttta cagattttat ttcataatta aaagatttta
     9301 ctacatttat gtttgatatc atttcttcaa tatgagcatt tagttttccc aactcaactt
     9361 gttgttgttt aaaaaaaact ctagttctct ttgcaataaa attactcaca aacattactg
     9421 tcggtattaa tattacactg caaaaagtta aaattggact taatacaaac atcataataa
     9481 aagtcatcaa tatgtttaag attcctgtaa ttaattgtac tagtgaattt gatattcctg
     9541 tactgatatt atcaacatca tttgttactc tgctcataat atctccagta gaactcttat
     9601 caaaaaaggt tattggtaga cttttaaatt ttaaaaataa attactcctc atctctttaa
     9661 ctatactttg ggataatcta gctgtacata tccccttaga cagtttaact gaaaactcaa
     9721 ttatataaaa tgaaagtaaa ataattattc cttttaagaa aatggatttt gaataagtat
     9781 caatatctat tatgtcaact acctttccaa tagtgtatgg gattacagtt gatataattg
     9841 aatcaattat tactagcaaa aaaataaatc tagtaatctt cttatctttc ttaaagtaca
     9901 taaaaattct tttaaaagtt tttttaaaat ctttaggctt ttcttttttc tttaatctac
     9961 tgaccttttg atttccagta cttaaattca atatacttcc tccttaattt acatcttcac
    10021 ttactaaatt ctgcaacgta aaaatttttt tataaattgg agaactaacc agtaaatctt
    10081 catgtgtagc aaatccaacc acctctccct catccaagac taaaatctta tcacagtcaa
    10141 ttatagaact aatcttttgt gaaatagtta ttactgtaca tttcttacct tcattttctc
    10201 ttaaattgct tatatgatct tttatattct ttcttataat tgtctctgta ttaatatcca
    10261 ttgcactaaa acaatcatca agaattaata tttgtggttt ttttgctatg gctctagcta
    10321 tagtaattct ttgtctttgc cctcctgata gatttttacc cctttgaaat aaaacttcat
    10381 cataagaatt ttcgagtttt gttataaatt gatttgcatt tgctatttca catgatttta
    10441 taacatcctc tttgcgtata tttctatttc ccataactac attctccaat atactttttc
    10501 caaacacact actattttga aatactacac ctattctttc tcttaaactt tcttcagaaa
    10561 tactgtatat actatgtcct ccaatcttaa tatcgccttt atcaattata tataattttt
    10621 gaattaaatt tactaaagaa gtctttcctg aaccagtttg accaatcaca ccaatatttt
    10681 gaccttcttc tattttaaaa gatatgtttt ttaatatttt ttcacctgta tttttgttat
    10741 acgcaaaatc cacattttca aaaattatat cacaatttgc aaactttaaa tctttttctc
    10801 caatatctga acttttatct ctctcaatta cttcttcatc ctcatcaatc aaaacctcac
    10861 ttattctctc ataagacgct tttgctctaa caaaaacatt aaaaacatgt gaaatcatta
    10921 taagagatgt taatattcta gtcatatagt ttacataagc aactataatc ccaattttaa
    10981 tttctcctga ataaattaaa tatcttccaa tcagtaatat tattattatt gaaacattaa
    11041 tgattattgt aattgtaggt ctaaaaaatg acatcatagt tgtagctttt ctactatttt
    11101 taaaaagctc ataatttaac tcttcaaaac ttttgttctc ataatcgtat ctgcaaaata
    11161 gtttaactac ttttattcca cttaaaaact gtcttaattt tgaatttact ttatctgtac
    11221 tttcttgtac atttttaaat aatctatacc ctaccttcat attaagcaat attataataa
    11281 atataattaa aactgcaatt agaataatta ttgacatctt taagtttaat tttatggcta
    11341 taattaaact tcctatgcac attattggtg actttataaa aactctcatc atcccattaa
    11401 cgaattgttg catttgatta atatcattag taattctcgt tattaacgaa gctctaccaa
    11461 atttatctat ttgttttaac gagtatgtat ttatcttttc aaatacatcc tgtcttaaat
    11521 aataagaaaa atgctgagaa actcttgccg agattacact tcttattatt gcaaatattg
    11581 cacctaaaaa agttatacct atcattataa ctcctgttga tagaatgtaa tctaagttct
    11641 tatttgaaac tcctatatct attatttttg ccattatagt tggttgagct aaatcacaaa
    11701 aagcttccag tgtcaaaaaa aatactgctg ttagaaataa tactatatat ttttttatgt
    11761 attttttaaa atacctcatt caatcatccc ttcatagaat tttctcatta ccaaaagtat
    11821 atcataatgg ctaatttaat tgattatatc aattataaat atttgattta ttattaattt
    11881 ttataccata tattttataa attatttgtt tttatttcct atatttatat at
//
LOCUS       DAMKOJ010000096        11454 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.104, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000096 DAMKOJ010000000
VERSION     DAMKOJ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11454
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.104"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            172..1047
                     /locus_tag="PC592_003035"
     CDS             172..1047
                     /locus_tag="PC592_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HDF4056976.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGKEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDKVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            1065..2555
                     /gene="cls"
                     /locus_tag="PC592_003036"
     CDS             1065..2555
                     /gene="cls"
                     /locus_tag="PC592_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF4056977.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGIGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNIGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTEDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            2748..3032
                     /locus_tag="PC592_003037"
     CDS             2748..3032
                     /locus_tag="PC592_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDF4056978.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            3065..4693
                     /gene="groL"
                     /locus_tag="PC592_003038"
     CDS             3065..4693
                     /gene="groL"
                     /locus_tag="PC592_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDF4056979.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEERVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVIKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            4955..5695
                     /gene="larB"
                     /locus_tag="PC592_003039"
     CDS             4955..5695
                     /gene="larB"
                     /locus_tag="PC592_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HDF4056980.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYSHAEYEDLSK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLAAMINKL"
     gene            5779..6513
                     /gene="larC"
                     /locus_tag="PC592_003040"
     CDS             5779..6513
                     /gene="larC"
                     /locus_tag="PC592_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HDF4056981.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLKMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDESNLNENVKSKAKKIFMA
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATMEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDEFEFSPRQI
                     GYGIGHKKFEVPNMLRTVLGEKKKKN"
     gene            6543..6962
                     /locus_tag="PC592_003041"
     CDS             6543..6962
                     /locus_tag="PC592_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HDF4056982.1"
                     /translation="MSSEIYSYLYEKILGEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGELVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      7022..7123
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            7344..8879
                     /gene="guaA"
                     /locus_tag="PC592_003042"
     CDS             7344..8879
                     /gene="guaA"
                     /locus_tag="PC592_003042"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDF4056983.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIETVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            9225..9635
                     /locus_tag="PC592_003043"
     CDS             9225..9635
                     /locus_tag="PC592_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056984.1"
                     /translation="MGKINSYNKEMESILIFDIGGISVKNTFSEVKLFQVKPDRLDDF
                     EKLIVLVAEEQKQQTGCIDIKYLKRFYIFDNIKEQPRELTKIVKCVKYYSYWEFDTLE
                     NYSNATHWFFDTYSKEVFKLLIMPFDINCGNSIY"
     gene            9779..10060
                     /locus_tag="PC592_003044"
     CDS             9779..10060
                     /locus_tag="PC592_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056985.1"
                     /translation="MLFIVIYILILFTIYLVKKNEFIGYILARGMLKLCFIIGIMLSI
                     QTVFQLVNKIEIPVPALITKVLIFVVLAVFARYIERNLKGNFIYSNSDF"
     gene            complement(10099..10671)
                     /locus_tag="PC592_003045"
     CDS             complement(10099..10671)
                     /locus_tag="PC592_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4056986.1"
                     /translation="MINGDKISLIPATLDDRQKVYEWCFQSETTKSHSGLPNYPNIPI
                     ATYEEFCEEDYEEYFFTGAKPKDGRGFLIVSNTEPVGFISYSCFHLKQALAEIDIWMN
                     CEANCGKGFGVDAIISLGDFLNKTMDICELIIAPSRKNIRAVKAYKKAGFKPSTKPMS
                     DYLLDKYIPLYGTGDYGIDETVILVKQLDT"
     gene            11093..11335
                     /locus_tag="PC592_003046"
                     /pseudo
     CDS             11093..11335
                     /locus_tag="PC592_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
BASE COUNT         4514 a         1183 c         2132 g         3625 t
ORIGIN      
        1 ttttttattt aaggtaaaaa tttaaagtaa aatattattt tacataataa taaccttata
       61 aattttgaaa ttacttatct ttgtgttaaa ataagtaaaa tgcacatatt aaagctaagt
      121 ttttaagtaa ataaacaaaa tgaaaatata aatattaagg agatttagta tatgaatgtt
      181 tatgaaaaag gtaatggagt tatactagaa ggagtaacag attttgaccc agtacatata
      241 tttgagtgtg gtcaatgttt tagatggcac aaacaagaag atggctcata cactggtgtt
      301 gcaaagggaa gaatattaaa tgtcaaaaaa gagaatgata aaatatattt aaataatacg
      361 aatttaaagg agtttaatag tatctggtat aattactttg atttaggaac tgattataca
      421 gaaataaaga ataagctaaa aaatatggat gaatatttaa ataaggctac tgaatttgga
      481 tggggaataa gaatattaag acaagatgga tgggaaatgc tcatatcatt tataatttcc
      541 tctaataata ggattcctat gatacaaaga gctatagaaa atttatcaag aaaatttggt
      601 aagtatatag gtgaatatga aggtaaagaa tactatgcat tcccaacacc agaagagtta
      661 aataaggcct cacaagagga aataagagca tgtcaaacag gttttagaga taagtacata
      721 aaaagtacta cacaggcagt tatagagaat aatgataagg tatccgaata tacaaattta
      781 agtacagaag attgtagaaa agagctttta aaatttaatg gagtaggccc aaaagtatgt
      841 gactgtattg cattatttgg tatgcaaaaa tatgattctt ttccagttga tgtttgggtt
      901 aagagagtta tgcaagaatt ttatatagat gaagacatga gtttacctaa aatgagaact
      961 tatggaatcg ataaatttaa agaaatgtct ggatttgctc aacagtactt attttactat
     1021 gcaagagaac tcggtatagg aaaataaatt aagggggaga aattatggga gtaataggaa
     1081 caatatttct gttctattta attatatcat atctggctgg agccataatt tctgtgatta
     1141 tattacttga aaatagagat cctgcaaaaa caatgtcttg gctattaatg tttattatat
     1201 ttccaggtat aggtttaatg atatatgcta tttcaggtag aaatattaga aaaagaaaat
     1261 tatttaaaac tcaaaaacta gctaataata taaaagaaaa gaaacttttt gatacattag
     1321 aaaagataac agaaatagtt gaattagaaa aagaatctat aaaacaaaat aagcttttaa
     1381 gagacgaaga agatggtagt tatagaaaaa gggtaataaa tatgctatta aagactggta
     1441 tgtttccctt tactaaaaat aataaagtgg atgtgtttgt agatggaaat gaaaaattta
     1501 aaagacttat agaagatata agagaagcta aagaccatat tcatttagag tattttatca
     1561 tcaaagatag tgaaataggt agggtgttaa aagaggaact tataaaaaaa gctaaagaag
     1621 gtattaagat aagaatttta tatgatgatg taggatgctg gagattttgg tttaatagaa
     1681 agtttttccg agaaatgagg gaagtaggta tagaaattgc agcattttta cctacaaaat
     1741 ttcctataat aggaggaaaa ctaaactata gaaatcacag aaaaattgtt gttattgatg
     1801 gaataattgg atatacaggt ggaataaata taggagatga atatttagga aaaaatgata
     1861 agtttggata ttggagagat actcatatta ggattaaggg tatttctgta tacatgcttc
     1921 aaatgacatt tctgattgat tggtattata cgacaaaaga agtattagtg actaaaaatt
     1981 attttccaag tgtagggaat attggtgaaa gtatgataca ggttgttgcc agtggtccag
     2041 atagtgactg ggaagatatt cattatgctt atttttctgc aatatgtcaa gctagaaaaa
     2101 atgtttatat agaaactcca tatttcattc cagatgaaag tctattaaaa gctataaaaa
     2161 gtgctgctct tagtggagta gatgtgagaa taatatttcc taaaattgca gaccacaaga
     2221 tagtaaacat agcatcttat tcgtattttg aagaaatatt aagagcaggt ggtaaagttt
     2281 atttatataa taaaggattt atacactcta aagtcgtaat aatagatgat aaaattgctt
     2341 ctgcaggtac agccaatatg gacttaagaa gttttatgct taactttgaa gtaaatgcat
     2401 ttatctatga tgaagaagtt attagagtaa tgacagagga tttctttgag gatttaagcc
     2461 actgtgaaga acttaatttg gaggtattta agaatagaaa tatcatacaa aaaatcaaag
     2521 aatctgtagc aagattattt tcaccaatat tataaaaaat tattaaaaaa ggtattgaaa
     2581 attatgtgtg attggtatat tataataatt gttagcactc tattagatag agtgataata
     2641 aataaaaagt atatatataa atctacatat aaaagtagta ttaatttaaa aataactaaa
     2701 aacataggcg aactagtcta tacttaatat tttaggaggc gtaaataatg aaaataagac
     2761 cattagctga cagagtagta attaaaaaag tagaagcaga agaaaaaact gcaagtggaa
     2821 tagttttacc aggagcagct aaagagcaac ctcaaatagc tgaagttgta gaagttggac
     2881 caggtggaat agttgaaggg aaagaaataa aaatggaatt gacagtagga gataaggtta
     2941 tattccaaaa atattctgga acagaagtta agatagaagg acaagaatac acaatactaa
     3001 gacagagtga tgtattagct gttattgaat aaatatagaa taaatttatt aggaggagtt
     3061 taaaatggct aaagaaatta aattttcaga ggaaacaaga agagctttag aagctggtgt
     3121 aaataaatta gcagatacag taaaagtaac attaggacct aaaggaagaa atgttatatt
     3181 agataaaaaa tttggttctc cacttataac taatgatgga gtaactatag caaaagagat
     3241 agagttagaa gatagatttg aaaatatggg tgctcaatta gttaaagaag tagcaactaa
     3301 aactaacgat gtagctggag atggtactac aactgctaca gttttagcac aagctataat
     3361 aagagaaggt ttaaagaatg taacagcagg ggctaaccca atacttttaa gaaaaggaat
     3421 acaaaaggca gtaacagtag cagtagaaga attaaaaaat caatcaagaa tagtagaaac
     3481 acaagaggct atatctcaag ttgcttctat atctgctgga gatgaagagg ttggaaaatt
     3541 aatagcagaa gctatggaaa tagtaggtaa agatggagtt ataactgttg aagagtctca
     3601 aactatgaat actgaattag atgctgttga aggtatgcaa tttgatagag gatttgtttc
     3661 tgcatatatg gttacagatg tagataaaat ggaagcagtt ttaaatgatc catatatatt
     3721 aattactgat aaaaaaatat ctaacataca agagttatta ccagttcttg agcaaatagt
     3781 tcaacaaggt aaaaagttat taataatagc tgaagatgta gaaggtgaag cgttatctac
     3841 attagtagta aataaattaa gaggaacatt tgatgtagta gcagttaaag ctccaggatt
     3901 tggggataga agaaaagaaa tgcttcaaga tatagcaata cttacaggtg ctcaagtaat
     3961 atcagaagaa ttaggctatg atttaaaaga agctgattta tctatgttag gtagagcttc
     4021 atctgttaag gtaactaagg aaagtactac aatagtagat ggttctggag ataaaaaagc
     4081 tatagaagag agagtaactc aaattaaaca tcaagtagag caaactactt cagattttga
     4141 tagagaaaaa ttaatggaaa gattagctaa acttgctgga ggagtagctg taataaaagt
     4201 tggagctgct acagaagtag agttaaaaga aagaaagtta agaatagaag atgctcttaa
     4261 tgcaactaga gcagctgtag aagaaggaat agtagctggt ggaggaactg cttttgttag
     4321 tgttatacca gcaataggaa cgctaattga gagtttagaa ggagaagtta aactaggtgc
     4381 tcaaatagtt aaaaaagcgt tagaagaacc attaagacaa atagctataa atgctggtct
     4441 tgaaggtgct gtaattgtac aaaatgttgt taattctgaa gctgaaactg gatttgacgc
     4501 attaaatgaa aaatatgtaa atatgataga agctggtata gttgacccaa ctaaagttag
     4561 tagaagtgct ttacaaaatg ctgcatcaat agcaagtact ttcttaacta ctgaagcggc
     4621 tgttgctgac cttcctgaaa aagaagacgc aggaatgcca ggaatgggtg gcggaatgcc
     4681 aggtatgatg taatttaaaa aatttaaaat ataaatttta atataaagaa ctatttcgac
     4741 ttagatttta aactctaagt tgaaatagtt cttttgtata tatctagttt ttgtatattt
     4801 ataaattcaa tacacatatt tagataatca gtatctaggt tgtgataata tcttagagta
     4861 gtattgttat tttttaggtt atgattttag atatatatta attaaggtat aattgttgat
     4921 agagactaaa tcaaatttaa aaggatgcga taatatggac ttaagaaagt tgcttgaaga
     4981 agttaaaaat gaaaatattg atatagattt tgcgttagaa aaattaaaag atttacctta
     5041 tgaagacctt ggatatgcaa atatagacca tcatagagaa ttaagaaatg gttacccaga
     5101 agttatttat tgtgaaggta agagtgatga gcatatttta gggattattg ataaaatgaa
     5161 tcaaaaaagt tctaatatat tggggacaag gtgtagaaaa gaaacttttc taaaaattaa
     5221 agaaatctat agtcatgctg agtacgaaga tttgtctaaa attcttaaga ttcaaaatca
     5281 tgatatagag aatataggaa aaggtaaaat tgtgattgct acagggggaa cttctgatat
     5341 accagtagca gacgaagcct atcatacagc taagttttta gggaatgatg ttgatagaat
     5401 atatgatgtt ggagtggcag gtatacatag gcttttaaat aaaagacata aaatagatag
     5461 tgctagagta atagtagctg ttgcaggtat ggaaggtgct cttgcaagtg taattggtgg
     5521 actagttgat gttccagtaa tagctgttcc aacatctgtt ggatatggag caaattttgg
     5581 aggattagca gccttactag ctatgttaaa tagctgtgca tctggaatat ctgttgtaaa
     5641 tattgataat ggatttggag caggatattt agcagcaatg ataaataaac tataaataca
     5701 ttgatataaa ttaaacaaaa ctatataata aaatttaatt tctattatat ttttactatt
     5761 aaaattgagg agacatatat gagtgaaaaa atactttatt ttgatataat aagcggtata
     5821 tcaggggata tgacccttgc aagtttatta aatttaggtg tgcctaagga aatttttttg
     5881 gaggaaattc ataaactaaa aatgagcgat gaatttaata taaacatcag ctctaaaact
     5941 gaaaatggaa tagtaggtac aaaagtagaa gtaattacaa aagaaaaaca tacacataga
     6001 aatttagtgg atatatttga ggttatagat gaaagtaatc taaacgaaaa tgtgaaatct
     6061 aaagcaaaaa aaatatttat ggcaattgga gaagcagaag caaaagttca tggaactaca
     6121 atagacaaga tacattttca tgaggtaggg gctatagatt caattgtaga tatagtagga
     6181 gcttctatct tagttgattt actttgtgta gataaagttt gtgctagtac agtgtctgtt
     6241 ggctcaggat ttgtaaaatg tgaacatgga attataccta tacctgcacc tgcaactatg
     6301 gaaattttaa aaggtgtacc gattaaatta aataatgtaa atggagaatg tacaactcca
     6361 acaggagctg caatcataaa agtcttgtgt gatgagtttg tagacgagtt tgaattttct
     6421 ccaagacaaa ttggatatgg tataggtcat aagaagtttg aggtaccaaa tatgctcaga
     6481 actgtattag gtgaaaaaaa aaagaagaat taatttatga aattagtgca aacattgatg
     6541 atatgtcttc agaaatctat tcttatttgt atgaaaagat attaggtgaa aaagcattag
     6601 atatttatac agagagcatt tatatgaaga agaataggcc agcaacaaaa gtatcaattt
     6661 tatgcaatga atcagattta gaaaaattta ttaaaatatt acttttagaa actagtactt
     6721 ttggagtgag atataatgca tataatagag aaattctaga gagaaaattt gtgaaattag
     6781 atacaaaata tggagtggtt acagtaaaat tagggtatta taaaggagaa ctagtcaagg
     6841 cgactccaga atataatgaa tgtaaaacta tagcaaaaaa tgaagatatt cctataaaaa
     6901 aagtgtttgc tgatataaat tttagaataa aagaagaatt tagtgaaaac ttattgacat
     6961 aagtaataaa ttttgataaa ttaatattca gccttattaa ataaaagtaa aaagaaaaaa
     7021 atatataaaa tataaactca ctcgtatatg ctcagaaata tggtctgaga gtctctacca
     7081 agataccgta aatatcttga ctatgagtga aattattata ccaaaagacc tagttaagta
     7141 aatatgtagg ctgagttgta ctccctatgt gttggctata agataaaggt attttggaag
     7201 cctgtatagt aatttcactt ttgctagaaa ttatggaagt tactatacag gttttttgtg
     7261 taaaaagatt taatataatt tagactgtat tgtgttaaaa taaatatata aaaactatat
     7321 tatacaagga gagatgtgaa tttatgaaac atgaattagt acttgtaata gattttggag
     7381 ggcaatataa tcagttgata gctagaagag ttagagaaaa caacgtatat tgtgaaatac
     7441 ttccatgtac tgcaagcata gaaagaataa aagaaaaaaa tcctaaaggg ataatattta
     7501 caggtggtcc aaatagcgct tatttagaag attctccaac aatatcaaaa gaaatatttg
     7561 aactaggagt accaatactt ggaatatgct atggtattca aataatgtct catgtattgg
     7621 gtggagttgt aagaaaaggc aataaacaag aaaaagaata tggaaaaaca gctataactt
     7681 atggaaaatc atcattattt gaaggaataa ctacaaatag tgtatggatg agtcatacag
     7741 atttaataga aacagttcca gaaggattta ctatagttgc aaataccaat gattgtccag
     7801 tagcagctat ggaaaatgta gaacgaaacc tatatggagt tcaattccat ccagaggtag
     7861 aacactgttt ggaaggggac aagatactta caaacttctt atataatatt tgtaaagtaa
     7921 aaggtgactg gactacagat tcgtttatag aagataaaat aaaagaatta aaagaaaaaa
     7981 taggcgataa aaaagcttta tgtgctttaa gtggaggagt tgattcttct gttgctgcag
     8041 ttcttattca taaagcgatt ggggacaact taacttgtat atttgttgac catggtttac
     8101 ttagaaaaaa tgaaggaaat gatgtagaaa gaatatttag agagaaattt gatataaatt
     8161 taataagagt taatgcagaa gatagattct tatctaaatt aaaaggagtt tctgaaccag
     8221 aagctaagag aaaaataata ggtgaagaat ttataagagt atttgaagag gaatcaaata
     8281 aattaggaaa aatggatttc ttagtacaag gaacaatcta tccagatgtt atagaaagtg
     8341 gacatggaaa tgctgctact ataaagtctc atcataatgt tggtggaatc ccagaagatg
     8401 tagacttcca agaaattgta gaaccattaa gagagttatt taaggatgaa gttagaaaga
     8461 taggattaga gcttggtata gaagaaggat taatatttag acatcctttc ccaggaccag
     8521 gtctagggat aagagttata ggtgatgtaa ctaaagaaaa atgtgatata ttaagagaag
     8581 ctgatgctgt ttatatggat gagcttagaa aagcaggttt atatagagaa atatggcaag
     8641 cttttgcaac attaccagat gttaagactg ttggagttat gggtgatgaa agaacatatg
     8701 cttatctagt tggtttaaga gcggttactt cttctgatgg aatgacttct gactggtata
     8761 agatgcctta tgatgtatta gaaagaattt ctaatagaat aataaatgaa gttgatggag
     8821 taaatagagt agtttatgat ataacttcta aaccacctgg aactattgaa tgggaataaa
     8881 atatagaatg ataaaaatcc gtatgaacac aggatttgct ctatcttctt atcctatgct
     8941 atactagctt gatattattc atatttgcaa gtatcttgta gaataataag taaaaagagc
     9001 aaaaatgctc tgctgaacaa taaattcagc agagtatttt tttattttat tttgccgtgc
     9061 tcttgagctc caagcattag acatagatga ttttgttaga ttttggtttt attgtatcag
     9121 ctctgaaaag tgaattgata caataaaaag aggcatttat tgattattga tggagatata
     9181 tgttacgtta cttttgttgg aaatttgaga gatagcgtgg tataatgggt aaaataaatt
     9241 catataacaa agagatggag agtatactta tatttgatat aggaggtata tctgtgaaaa
     9301 atactttttc tgaggttaaa ttgtttcaag ttaagccaga caggctagat gattttgaaa
     9361 aattgatagt tcttgtagct gaagaacaaa aacagcaaac aggttgtatt gacattaaat
     9421 atttaaagag gttctatatt tttgacaata taaaggaaca gcctagggaa ctgactaaaa
     9481 ttgttaaatg tgtaaaatat tattcttact gggagtttga tactttagaa aactattcaa
     9541 atgcaacaca ttggtttttc gatacatatt caaaggaagt attcaagctt ttaattatgc
     9601 cttttgacat aaactgtgga aattcaattt attgaattga atagcaaatg agtagtatca
     9661 cctttggata atggaaagtc aaggtatttt cttatggatt ttgtggagtt aagacactcg
     9721 aagttatgta caggattctt tttttaaaaa acctattttt attggtttaa atttgacaat
     9781 gctatttatt gttatctata tattgatttt gtttacaata tatttagtca agaaaaatga
     9841 atttataggg tatattttag ctcgaggaat gttaaagttg tgttttatta taggtattat
     9901 gctttcaatt caaacggtat ttcaacttgt gaataagatt gaaataccag ttcctgcttt
     9961 aattactaaa gtgttaattt ttgttgtttt ggcggtattt gctagatata ttgaaagaaa
    10021 tctaaaagga aatttcattt atagcaacag tgatttttag atgtagtaat gaatgttgat
    10081 gttaaaaaca acctctgact aagtatccaa ctgttttact aaaataacag tttcatctat
    10141 tccataatct ccagtcccat agagaggtat gtatttatcc aataaataat cactcattgg
    10201 tttagtagat ggcttaaatc cagctttttt atatgccttg acagccctta tattttttct
    10261 tgatggtgca ataattagtt cgcaaatatc cattgtttta tttaaaaaat ctccaagtga
    10321 aataatggca tctactccaa aaccttttcc acaattagcc tcacagttca tccaaatgtc
    10381 aatttctgca agagcttgtt ttaaatgaaa acaagaatag ctaataaatc caactggttc
    10441 tgtattactt actatgagaa aacctctgcc atcttttggt ttagcaccag tgaaaaaata
    10501 ctcctcataa tcctcttcac aaaattcttc ataagttgca ataggtatat ttggataatt
    10561 aggtagccca gaatgagatt ttgtagtttc agactgaaaa caccattcgt atactttttg
    10621 tctatcatct aatgtggcag gaattaaact tattttatca ccatttatca taatttttct
    10681 ctccagtctt cacatagttt aatatttact tacagtataa gcttaaattg ataaattcta
    10741 acttacatat attgtaacat atccaaaata cataatcact gaatattgtt atgtcgtaat
    10801 agatttatgt aatacagtgt tagaaaatat cacatatcaa aaacatcaga attttactag
    10861 aaatagtata ttttatttat atttaatatt attcataatt ttttatattc ccctaattaa
    10921 aaactctttg gtatacttat aaataaactt aatgatagaa taaaaaagct ttataactat
    10981 tagatgcata gaaaagcatt ttatgtctat gaaatgtata tctataaaac atatagatga
    11041 cttttatata ttaatgtatt aatattgata ttatagaaga attgagttgt caataatact
    11101 aaatcaaata tctatagaat atggagggat tatgaaaaat aaaataatta taggaattac
    11161 tttttcactt gtattactaa tgtctggatg tgtttcaaaa caaacagcag aaataaacgt
    11221 attagcaact actgatttac atggagttat accttatgag ttaacttctt atgtaaaaga
    11281 agaaagaaaa aaagataaaa atctaacttt agtagatgca ggagattttt ttgattaaaa
    11341 aatagctaca tacactcgta actttagtta tgagttagta gctaaaatag tcagcatata
    11401 gggaaactta tatgtagaga taggataaca cctatccaat actacttgaa ttgc
//
LOCUS       DAMKOJ010000097        11059 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000097 DAMKOJ010000000
VERSION     DAMKOJ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11059
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.106"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            116..1147
                     /locus_tag="PC592_003047"
     CDS             116..1147
                     /locus_tag="PC592_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF4056987.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGLT
                     LDVDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLAIRNHWNSCDFDECSRIVNFKLDLYDKENDLLIKVADVVRDCL
                     NIEDNNEKLFKCSLFNKEIGLVYDNCFNLLKKLEYRFDVKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            1280..2578
                     /locus_tag="PC592_003048"
     CDS             1280..2578
                     /locus_tag="PC592_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF4056988.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVREGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVNFDDVNIKKSDINSQIYDCTVMKENYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLIKTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKD
                     RKLTLLIGMLEDKDIDSVLEVLLPHFNKVITTTPINPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(2698..2943)
                     /locus_tag="PC592_003049"
     CDS             complement(2698..2943)
                     /locus_tag="PC592_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF4056989.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            3091..3957
                     /locus_tag="PC592_003050"
     CDS             3091..3957
                     /locus_tag="PC592_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF4056990.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(3961..4497)
                     /locus_tag="PC592_003051"
     CDS             complement(3961..4497)
                     /locus_tag="PC592_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF4056991.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(4688..4891)
                     /locus_tag="PC592_003052"
     CDS             complement(4688..4891)
                     /locus_tag="PC592_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF4056992.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            5182..5946
                     /locus_tag="PC592_003053"
     CDS             5182..5946
                     /locus_tag="PC592_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4056993.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESRPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            6336..7649
                     /gene="prdC"
                     /locus_tag="PC592_003054"
     CDS             6336..7649
                     /gene="prdC"
                     /locus_tag="PC592_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF4056994.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQDDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      8052..8137
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            8668..10782
                     /locus_tag="PC592_003055"
     CDS             8668..10782
                     /locus_tag="PC592_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HDF4056995.1"
                     /translation="MNTIYVFSIRRILKTKIKKSSIISVVIAFSMVFTAFTPIVSYAD
                     EVIGNDTIINGEKPLEGQTPEGEKPLEGQIPEGEKPLEGQIPEGEKPLEGQTPEGEKP
                     LEGQTPEGEKPLEGQTPKGEKPLEGQTPEGEKPLEGQTPEGEKSLEEEIVIEEMSLKQ
                     DIDKILDMTLSQINKIVYNFWEDEENVKSDEQSEINQVFTSKDSFISLWYDKKAKVKN
                     TCLLKEIDGSDRPYHDLRFDDITKTLTFDYVIKGLVGASSKDNKYVIEGEDGEQTAFC
                     YNNHLRPPSSNGKSPYLPAEEFSGQENQNEDAVKSILYAGSEFDGFGYKQQFNLGGEE
                     NDIMTYSATQSAIWIILGQVDEQEKLKQYQGSINFCDFLIENAKNEEEKAEYQKKKEV
                     AINTKAYLEALLKAGREELKPNDTGKPSLSNGLTKINFEKNEDGTYETEAVALVGYSG
                     VVKLRLPDGVTAYDGDGNIIGTGEVEISTQQKFKLKSVGKPDAKANISAISYDYIFPK
                     AIQYYKAVIDLGQKDHSSSLPSSKQNLLSYTVEKKNGQEVNFNISLPTDDVVNPPVPP
                     TDDTVINPPVPPTDNTNGHKPKPSPPIDDTVINPPVPPTDDTVINPPVPPTDDVVLNP
                     PVPPTDDAVLNPPVPPTDDAVLNPPAPPVSDTVEKMPELSKYDTIVKSPKTGDETQLM
                     SYVFISIIAICGLAYQFKIKRN"
BASE COUNT         4490 a         1227 c         1896 g         3446 t
ORIGIN      
        1 tagtgtactt attttatgtt tttagcaaga aatatagcat ttaaaagata aattgtgcaa
       61 cttaaatcaa agtttaagat gaactattaa catagatata ttaaaaactt ttgtaatgga
      121 gaatatatgt gatatgaata ataaagttaa ggttgcagta ttagatacag gaatagacaa
      181 agaacatgat tacttaaaag ataatttagt tggaggaatt gcttttgaat gtatgcatga
      241 ttatatcttt atatcagata aatttgatga tgaagatggt catggaactg cttgtgcatc
      301 aataataaag aaagagtatg aagatgtaga gttatttgta ataaaaattt tgagaaaaga
      361 tggtattaca aatataaaag ttcttgaaga agcattaaga taccttttag acactaacat
      421 aagattaatt aatttaagtt tatcagtcat aggagtagaa agtgttaagg gtttgtttga
      481 agtttgctat gaattgttta gaaaaggaaa gataatagta tgttcactcg ctaatgattt
      541 tgacttaagt tatccagcta tgtttaacaa tgttataggt gtaaggggac ttactttaga
      601 tgtagatgat tcattttggt acaataaaaa atatgatgtt caatgtgtta tggatagcaa
      661 ttcatatata agttgtgaca taaataattc ctatagattg ccaccaaaat gtaatagtta
      721 tttgtcagca aagcttactg gtaaaatagc taagatatta tcagaaaaac caggcataac
      781 aatatctgat ttaaatgata agcttgaatc attagcaatt agaaatcatt ggaatagttg
      841 tgattttgat gagtgtagta gaattgtaaa ctttaaattg gatttgtatg acaaagaaaa
      901 tgatcttctt ataaaagttg ctgacgttgt tagagattgt ttaaatattg aagataataa
      961 tgaaaaacta tttaagtgta gcctttttaa taaggagata ggtttggttt atgataattg
     1021 ttttaattta ttgaaaaagc tagagtatag atttgatgta aagtttaatt atatggatat
     1081 ctcaaaatat gacttagttt caatatatac actgactgaa ttagtggaaa gatataaaaa
     1141 cttataaata aagatttgta gctaaattta atgtagaagg tattaaatta tatatatcct
     1201 ttgtcagtag attaaaagca aaaaatatac tataattaga tagcataaga gaaaatgcca
     1261 atacaggggg aattagataa tgaaatatga agaagcatta gagtatatat cacaaactaa
     1321 taaattcggt ataagattag gtctagaaaa tataggaaag ttattagaat tattaggaaa
     1381 tccacaagaa actttgaata taatacatgt agctggaact aatggaaaag gttctgtgtg
     1441 ttcttttgtt tctaatatac taagagagtg tggatataaa gtcggtttat atacatctcc
     1501 atatttagaa acttttactg agcgtataag ggtaaatgga cagaatatac cacaggatga
     1561 tgttgctaga ataattgaat taataaaaga aaaaatagag attatggtaa gagaaggcta
     1621 tgcatatcca acagagtttg aagtggttac tgcaatggca ttttattact attcagagca
     1681 aaaggtagac tttgtggcat tagaagttgg tttaggtggc agatatgatg ccacaaatat
     1741 aataacaaaa tcacttgtaa gtgtaatcgt atctataagt ttggaccata cagggatact
     1801 tggagataca atagaaaaaa tagcgtatga aaaggctgga ataataaagg aaaatggagt
     1861 agtactagta tatgaccaga ctgatgaagc aaaggatgtt ataaagtcag tttgtaagga
     1921 gaaaaaagct aaatatatag aagttaattt tgatgatgta aacataaaaa agtcagatat
     1981 aaattctcaa atatacgatt gtactgtaat gaaagaaaat tatagagacc ttgaaataaa
     2041 attaataggg gaacatcaaa taaacaattc tatattggca attagtgtaa taaaatatct
     2101 aaaagacata aataaattag caaatataaa tgaagaatct ataagaaaag gacttataaa
     2161 gactaaatgg ccaggaagaa tagaaaagat aaaagaaaat ccaattttta taatagatgg
     2221 tgcacataat gaagatggag caaaatcttt ggcaaaagca cttgataaga attttaaaga
     2281 tagaaaatta accttattaa taggtatgtt agaagataaa gatattgaca gtgttttaga
     2341 ggtattgtta ccacatttta ataaggtaat aacaacaaca ccaatcaatc caagggccat
     2401 aaattcagat atattaaggg aaaaagtatt aaaatatgta gatgatgtaa catcaaagca
     2461 tgagatagag gatgcagtaa attatacatt agaaacgtca agtgaagatg atattataat
     2521 aagtgcaggt tcattatata tgattggtac agtgagaact ttagtaaaga aattataatt
     2581 ttataaaata aatatacaaa tataaataaa agtataaaag agagttgtct aaaaaatgga
     2641 caactctttt tatataaagt aagtttttaa taattttatt gatatttata gaagcaatta
     2701 tatagattga cgtatagctt tagataattg gtctgggcaa gaagtacctt ttccaccaca
     2761 atcaataccg tttaatttat cagcaacttc aagagcattt tgaccaatta ttaagcttct
     2821 aagtcctgat aaattaccat tacatccccc tataaattca gcatcaacaa tcacattatt
     2881 ttcatcaact tcaaaaatca tttctctaca acagacacca cttggattaa atgttacttt
     2941 cattaaaaag acctccatta aattttattt ctttttttaa cattaataat aataccaaat
     3001 atatgagtaa taatgcaact ataaagcata atacaagcta atgaaataat atattattgt
     3061 agtatatgta ttgtagagag gaggggttat atgaaaatct atatttctaa ctatttatca
     3121 aagagcatta gcatagttga ttattctaca cttgaactag aaaaagaaat agtattagaa
     3181 gataatatat atccacacca tttttgcata gaaaaagaaa aaaatttaat atacatacct
     3241 agttcaagta atgggatact ctatgtctta gatttaagca atgataaaat aattgatact
     3301 gtttctatag gtggaagtct tagtcaagtt gtacttagcg ataatgaatt atttgtagca
     3361 aatgaagatt ctaatagtat atatgtacta gataaaaaca cattaaatcc aataggaatt
     3421 attggagttg ataatatgcc acatggattt gactttgata gagaaagtaa aaagttatat
     3481 gtaccgtgta taaactcgat agtatgtata gatacaatta ataaaaatat acaaaagaaa
     3541 ataaatatgg actttagagc ttggcatata gaacttgata aacaaaagaa agaaatgtat
     3601 atatcaacac ttgatggaaa gcttataata atagatgaag taagcatgga tataaaaaag
     3661 gtattatatg aatttttatt accagtagaa ataagattta attatagtgg caaaaaagtt
     3721 tatgttgctg atttgggata taataatgta agaattttag attatacaac gagtagatac
     3781 attggaaata ttgaaataaa tgggattcct cagggcttag aaatatctaa agatgaaaag
     3841 ttactatttg tatcagatac acaagaaaat tcagtaaaag tttatgaaac tgcaaataac
     3901 aaattaataa aagaaatcaa ggtaggaaaa gagcctacaa ctataatttg tttgtaggct
     3961 ttaatgtatg tctcttataa gtaagtcgat aacttcggca tacatataag atgcattatt
     4021 tttccagtta ttgcaaataa gttttgcttg tttctctgat gaaacattta gatttaaatc
     4081 tattaagtta gactgatttt ctatgactct aaggttaaca ataaattcat tatcactttg
     4141 ttttacaaaa ctagacttta cttgagtatc tgctagtaaa ttttctttgt tagaatctat
     4201 atacttgtct attttttcag taacactagt aggtattcga ttaaagaagt attccagact
     4261 ttctacgcct ctttgagtaa gagcataata ttctctgtca gagtctttat atgtagtcaa
     4321 aaacttagat tccataagct gagataaaag ctgttgtaat gaaaaataat tcatcatttc
     4381 agtctctaat actacttgag ttatttgaga attagttaaa tccattttaa ttttttctaa
     4441 tatatataaa attaaaagtt tgtgataggc taattcttca gacgagtttt caaacataaa
     4501 tatcatcctc cgtcaaacta tttctatata taatatatta aactaatttg tacaaaatta
     4561 aaagaacaat ttgtattgta ttattaatct ttaataattc atataaaaac aattttataa
     4621 ataaatatag agaaacaggg ctactaatta gcagccctgt tgatacccag gtgtcaaaat
     4681 ttactattta ttttccagcc atttgtcttt cagccatttc aactaatttc ttagtcatat
     4741 atccaccaac atatccattt tctctagctg ttaagttacc tttgtctatg ttttcatagt
     4801 tagataaacc tatttcatta gctatttcta atttcatttg gtttaaagca gcttttgctt
     4861 ctggaactac tgttctgttt gaatttgaca tagtaaattt cctcctcaaa taattagttt
     4921 atgatgtcta acaacacttt tatttatgtg atgttaatac taatttctcc aaaataaaaa
     4981 taatatatac agaaaaataa aggtaaaaat gtaaaaaata taaaaaaatt aaacaaacga
     5041 gtattttaga gagtttaatt aggtcaatat aggttttatt tttttagtta ttgtcttata
     5101 aattaaatat tacagtactt ttttgagctg aaaaaaaata aattttaaat atagaagaaa
     5161 ttatttaaaa gggggaatag tatgaaaaga gaagttaaaa ggactaaagc tttgatatat
     5221 agtgttttat ttttttcatt attattagtg ttaatatttg tttttgttta tggaataaaa
     5281 tacatatgtt ctaaatctga caattcaaaa atgcctatat ataaagttga tacaaatgag
     5341 aaaaaaatag ctttgagttt tgatgtagca tggggaactg ataatatgga tgatatttta
     5401 aaaattttag ataaacataa tgtaaaagct accttttttt tagttggtag ttgggtagat
     5461 gataatgaag aaattgtaaa agctatagat gaaaagggac atgaaattgg aaatcattca
     5521 aatactcatg ccaatttgaa ggaaatatca aaagaagaca taacaaaaga gatagaaact
     5581 acatcagaaa aaatatataa tataacagga aaaaagacta atttatttag acctcctttt
     5641 ggggatgtaa acaacaaagc tatggacatt tgtagtgatt taggttataa agtaattaag
     5701 tgggatgtag attcgataga ttggaaggag cttggaccaa atcacgtaat tgaaaaagta
     5761 ataaaagaat ctcgaccggg ttcaatagtt ttatttcatg cgaatataaa tgatgtagat
     5821 aactatttgg atactataat aagtcgacta aaaaaagatg gatacagtct agtcaaaata
     5881 tccgatttgt tgtataaaga taattatgta gttgattcca atggagtgca aaaaactaag
     5941 aattaataag taataaatgt atattttaag caaagttgtg gtaaattata tagtatatgt
     6001 tagaaaagtg tcgataaaaa gacggtgtct attttttgac actttttata catgtatgca
     6061 atatcaataa ttatagatta aattgattga aaaaagtgtc taataattga cttttttttg
     6121 acgggcttaa aaatttagaa gaattaataa atgctgtaag atagtatttc caaagggtat
     6181 aagtttattt gaaagttggc atagaaattg ctttgttaat aagcgatatg ttctatagaa
     6241 ataaacgata tgttaagacc ttataataga aaaatagcat taacattatt tgaacagctt
     6301 ataaaaaaat taatatactt aagggggcgt actagttgaa caaactatat tctattttat
     6361 taaaacaaca cgttggtggt ccagataagc cagtagtaag tgttggagat gtagtaaaaa
     6421 aaggaactct aatcgcagaa ccaactggat taggggcaaa tatttatgcc agtgttagtg
     6481 gaaaaataag tgaaataaat gaccaagcga tagtaattga agctgatgaa gtacaagatg
     6541 atacttttga accattaaaa ggagaaggta tacttgactt aattaaagaa gctggagtag
     6601 taggaatggg tggagcagga ttccctactc atgtaaaatt aaacatagat ttaaatggtg
     6661 gaacaatatt agcaaatgca gctgaatgtg aacctttatt agctcataat ataaaagaaa
     6721 tagaagaaag accagaaata gtttatcaag gtataaaata tgctatggaa gttactaatg
     6781 ctggaaaagg tatgctagca ataaaaagca aacatccaaa agcaatagaa gctttcaaaa
     6841 aagtaataaa gccaggagac aacatagaag ttgcagaact agttgatatg tacccaatgg
     6901 gagaagagag agcaatagta agagacgttt taggaaaatt acttgagcca actcaattac
     6961 cttcagaggc taatgcagta gtaataaacg tagaaacatt aactagaata gtagaggctg
     7021 ttgagcaaaa aagaccagtt atatctaaaa atataactgt agttggtcaa ttaaatagtg
     7081 gaaaagagtc tatagtattt gaagatgtgc caattggaac aactgttgga gaattaattg
     7141 aaagagctgg tggaataaaa ggtgaatatg gtgaaataat cttaggagga cctttcactg
     7201 gtaaagctac tactttagat gctccaataa ctaaaactag tggtggtata atagttacta
     7261 tgccatttgt taatgaaaag agaaaaatgg gtcttttagt ctgtgcatgt ggacctaatg
     7321 aagagagaat gagagatata gcaactaaaa tgggagttac tgatatagta tcagttcaaa
     7381 aatgtaaaca agctcaagaa attaaaggtg cattaaaatg cgaaaatcca ggacactgtc
     7441 caggacaagc tcaaaaatgt atagaattta agaaagctgg agcagaagtt atattaatag
     7501 gaaactgtac tgactgtagt aacacagtaa tgggttctgc accaaaatta aaattaggtg
     7561 tatatcatat tactgaccat gtaatgagaa cagttaatca cccattaata agaagaataa
     7621 aaggtgatgt aagattaaaa ataaaataat agataaatag aagctaaaca tccttagaag
     7681 taaaacttaa aagttacttc taaggatgtt ttttaatgta ctttgagggt aagatatatt
     7741 ttaaaataaa tggaaaaaat agacaaaata tactagatat tgtataatga taacaatagc
     7801 tattacaatt aatattggac aaaaataatg atactcaaat atgtgatttg tattgatatg
     7861 tatattatat taagtcaact atccaataga gtaaaaggtt tttgtgacat ttgaagatac
     7921 tctatagtat cttttttagt gtaaaaacta agttttgtct tttattagat aagtatcttg
     7981 gatactagtt tatattttat taagttgtta aaaaagtgca cttaaaaagt taaaaaagaa
     8041 aaattaaaaa acctatttat agaaactgtg aagtatatct taaacttggg cacttaaaag
     8101 atatatggag ttagtagtgc aacctgctat aaatataaat aggagtaact tttaattgtc
     8161 aaaaatatat aaaatacata aataagtaat tagtagaaga tagatataaa tatatttttg
     8221 aaatgctccc tacattcata acgagtgtag agtggcagat acctgcccaa aactccttta
     8281 attgctggaa gttcctaaag ctaactaaac cacaacataa tcatgaaata aggataagtg
     8341 tgatagagtg tgtatttaat aagcacttaa ggttacgaaa gtagaaaaaa ttagttagat
     8401 agcataaggt taaatcctaa gtgccttgaa aatggataat cagcaggtaa gcttcgaaaa
     8461 gaagaaactt caacgactag agagaaatct cgtacctaca agtgtgggga aatggggagt
     8521 acctaattta tggttaggta atgatatagt ctgtgcttaa tagaaatatt aagaagttca
     8581 taggagaact ggttaggagt aacgccccta attgaacaca ctaaagatat attgttgaat
     8641 aagattcata taatatttaa ttattaaatg aatacaatat atgtttttag tatcaggaga
     8701 attttgaaaa caaaaattaa aaaatcaagt ataatcagtg tggtgattgc ttttagtatg
     8761 gtatttactg catttacacc aatagtatct tatgctgatg aagtaatagg caatgataca
     8821 ataattaatg gagagaaacc attagaaggt cagactccag aaggagaaaa accattagaa
     8881 ggtcagattc cagaaggaga aaaaccatta gaaggtcaga ttccagaagg agaaaaaccg
     8941 ttagaaggtc agactccaga aggagaaaaa ccattagaag gtcagactcc agaaggagaa
     9001 aaaccattag agggtcagac tccaaaagga gaaaaaccat tagaaggtca gactccagaa
     9061 ggagaaaaac cattagaggg tcagactcca gagggagaaa aatcattaga agaagaaata
     9121 gttatagaag aaatgagtct aaagcaagat attgataaaa ttcttgatat gactttatct
     9181 caaataaata aaatagtata taacttttgg gaagatgaag aaaatgtaaa gtcagatgaa
     9241 caatcagaaa ttaaccaagt ctttacttca aaagactcat ttatcagctt atggtatgat
     9301 aaaaaagcaa aagtaaaaaa tacttgttta ctaaaagaaa tagatggttc agacagacct
     9361 tatcatgatt taagatttga tgatattaca aagactttaa cttttgacta tgtaataaaa
     9421 ggtcttgtag gagcaagctc aaaagataac aaatacgtaa tagaaggtga agatggagag
     9481 caaactgcat tttgctacaa taaccattta agaccaccaa gtagtaatgg aaagagtcca
     9541 tatttaccag cagaagaatt tagtggtcaa gaaaaccaga atgaagatgc agttaaatct
     9601 atactatatg caggttctga atttgatgga tttggatata agcaacaatt taatttaggc
     9661 ggagaagaaa atgacataat gacttactca gccactcaaa gtgcaatttg gattattctt
     9721 ggacaagtag atgaacaaga aaaacttaag cagtatcaag gctctataaa cttttgtgat
     9781 tttcttatag aaaatgcaaa aaatgaagaa gaaaaagctg agtatcaaaa gaagaaagaa
     9841 gttgcgataa atacaaaagc ttatttagaa gcattgttaa aagcaggtcg tgaagagtta
     9901 aagccgaatg atacaggaaa acctagttta agtaatggtt taactaagat taactttgaa
     9961 aaaaatgaag atggtactta tgaaacagaa gctgtagcct tagtaggtta tagtggtgta
    10021 gtaaagttaa gactaccaga tggagtaact gcttatgatg gagatggtaa tataataggt
    10081 acaggtgaag tagaaatttc aacacaacag aaatttaaac ttaagagtgt tggaaaacca
    10141 gatgccaaag ctaatatttc tgctatatct tatgattata tttttccaaa agctattcaa
    10201 tattataagg cagtaatcga tttaggacaa aaagaccact catcttcatt gccatctagt
    10261 aagcaaaatt tattaagtta tacagtagag aaaaagaatg gccaagaagt taactttaac
    10321 ataagtctac caacagatga tgttgtaaat ccaccagtgc caccaactga tgatacagta
    10381 ataaatccac cggtgccacc aacagataat acaaatggac ataagcctaa accttcacca
    10441 ccaatagatg atacagtaat aaatccacca gtaccaccaa ctgatgatac agtaataaat
    10501 ccaccagtgc caccaacgga tgatgtagtg ctaaatccac cagtaccacc aacagatgat
    10561 gcagtgctaa atccaccagt gccaccaaca gatgatgcag tgttaaatcc accagcacca
    10621 ccagtaagtg atacagtgga aaaaatgcca gaactatcaa aatatgacac aatagtaaaa
    10681 tcaccaaaaa caggtgatga aactcagcta atgtcatatg tatttattag tatcattgcc
    10741 atttgtggat tagcttatca atttaaaata aaaagaaatt aatctagatt attattaagt
    10801 ttaaaataaa aagtctcaaa ttgatttata agtcattttg ggactttttt atgtaaatat
    10861 aatatgtaaa tatagcttgt ttaaaagtat ctattttaat tatattctta aacttatgat
    10921 tagatatagg tattcattag ttgtttgatg aatagaaaaa tgttttgaag gtgaaaatag
    10981 tattgaaaaa ataatatact aagggtataa ttcatttgat ttcatttgta taaatttaat
    11041 tataaatttt aaattgatt
//
LOCUS       DAMKOJ010000098        10931 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000098 DAMKOJ010000000
VERSION     DAMKOJ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10931
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.107"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            309..1508
                     /locus_tag="PC592_003056"
     CDS             309..1508
                     /locus_tag="PC592_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HDF4056996.1"
                     /translation="MEKLYYTDQYIKDFTAEIVEIKEVENKFHVLLDKTAFFPGGGGQ
                     FADLGKIDNYDVISVYEEGKKVYHVLDKKPIKIHRVKCSIDWNRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGSEYSTVDIEGNLDEDKIREIELLSNEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVVKIGDLDTNACCGVHPKATGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDDILKRDIYLTKICRYLSCNEEDAINGIVNLNSKVEEVLIKKRRLE
                     EVVSTYQVKEMIEKANKIGNISVVKKIYEDEDLKYVNKIANKITEHENNIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKILAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            1560..2060
                     /locus_tag="PC592_003057"
     CDS             1560..2060
                     /locus_tag="PC592_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4056997.1"
                     /translation="MEQQKDYIELYENEELIEIREACMNDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENMSAKATYESLNMYECDYNMY
                     EYEVMR"
     gene            2162..2479
                     /locus_tag="PC592_003058"
     CDS             2162..2479
                     /locus_tag="PC592_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4056998.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASIFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     IIQ"
     gene            2637..3596
                     /locus_tag="PC592_003059"
     CDS             2637..3596
                     /locus_tag="PC592_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF4056999.1"
                     /translation="MGESKKSENLLLSIIYIIFFVYILMIIRIILFRDVPIYAISKGT
                     FRTVNLIPFYTIYQFIVDSNIDFMKATINIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     TIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGITIYINMNKLFPNDIKRFKVII
                     ATSLILGVIGLGVISKNYHNLLTFKFRPDKKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            3711..4496
                     /locus_tag="PC592_003060"
     CDS             3711..4496
                     /locus_tag="PC592_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF4057000.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGIMSVLIIRFIHPFIKDFVGIIPYRILISMSIITTLWAILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            4788..6107
                     /locus_tag="PC592_003061"
     CDS             4788..6107
                     /locus_tag="PC592_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF4057001.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(6181..6615)
                     /locus_tag="PC592_003062"
     CDS             complement(6181..6615)
                     /locus_tag="PC592_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057002.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RRKDDKKKGNKKRNTNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAIL
                     IITKLTDSTNKGTYSRNTVSNTHKNDIRNVVFNESNNFLICG"
     gene            complement(6706..8082)
                     /gene="hydG"
                     /locus_tag="PC592_003063"
     CDS             complement(6706..8082)
                     /gene="hydG"
                     /locus_tag="PC592_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HDF4057003.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLISEEIDKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(8083..9168)
                     /gene="hydE"
                     /locus_tag="PC592_003064"
     CDS             complement(8083..9168)
                     /gene="hydE"
                     /locus_tag="PC592_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HDF4057004.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDTYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(9204..10412)
                     /gene="hydF"
                     /locus_tag="PC592_003065"
     CDS             complement(9204..10412)
                     /gene="hydF"
                     /locus_tag="PC592_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HDF4057005.1"
                     /translation="MSLNSTPQSIRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGKLGELRISKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLAKNKVKCPVVSVSSTDKIG
                     IENLKNEIIRVLPKDGTEFRLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKENSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALETLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(10427..10678)
                     /locus_tag="PC592_003066"
     CDS             complement(10427..10678)
                     /locus_tag="PC592_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HDF4057006.1"
                     /translation="MKKVAVISAILEEPKECQLKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDIINSLTGKLGNIPHVSVKTSISKKEI"
BASE COUNT         4059 a         1322 c         1677 g         3873 t
ORIGIN      
        1 tatattgaaa attattaata atagatgaga ttagtaaaag tgattaaatt taatttgtag
       61 gtttaatata tttcggtaaa ttttttatat tgtaagaaga catggaagca tatacatttg
      121 taaaatatcg aaataatata cttataaatt tgttaacact aatatctatg tgttaaaata
      181 tagtataaga ttgttagcaa agaatgggat tagttctatc ctagtacaat taaattaaag
      241 ttatactaag atttgtatat ttaaaaacta aagtagttta gaactaagga aatggagata
      301 gaattataat ggaaaaatta tactatacag accagtatat aaaagatttt acagcagaaa
      361 tagttgaaat aaaagaagta gaaaataagt ttcatgtttt gttggataag acagcgtttt
      421 tccctggtgg tggaggtcag tttgcagact taggaaaaat agataactat gatgtaataa
      481 gtgtatatga agaggggaaa aaagtatatc atgtattaga taaaaaacca ataaagatac
      541 atagagtaaa atgcagtatt gattggaata gaagagaaga tggtatgcat caacactttg
      601 ggcaacatgt actgtcaggt tgttttttta agactttcaa tgcaaataca acaggttttc
      661 atctaggaag tgagtatagt acagtagata tagaagggaa tttagatgag gataaaatta
      721 gagagataga gttgctttct aatgaaatta ttcgtcaaaa tatacaagta gagacgctac
      781 ttccaacaaa aaaagaattg aaaaagattt ggttaagacg tgatttgcca aatactgatg
      841 aagaaataag agtagtaaaa ataggagatt tagatacgaa tgcatgttgt ggagtacatc
      901 caaaagcgac tggtgaattg agaatgataa aaataaagaa atgggaaaaa cataaatcta
      961 gtacaagaat agagtttttg gcaggtaaaa gggcagtaga tgatatatta aaaagagata
     1021 tatatttaac taaaatatgc agatacttaa gttgtaatga agaagatgct ataaatggta
     1081 ttgtaaatct aaatagtaaa gtggaagagg ttctaattaa aaaaagaaga cttgaagaag
     1141 tagtgtctac atatcaagtc aaagaaatga ttgaaaaagc aaataagatt ggcaatattt
     1201 cagtcgttaa aaaaatttat gaggatgaag atttgaaata tgtaaataag atagcaaata
     1261 aaattacaga acatgaaaat aatattgcat tattagctgt taaatttaat gataaaataa
     1321 atttagtttt tgcatgttct aaaaatttaa aagatattaa tatgggagtt ttattaaagg
     1381 atgcaataag ccttatagat ggtaaaggtg gtggaagtaa aatattagct caaggaggag
     1441 gtaagaataa tggaaattta gaagctacac ttgactatgc atttatgaag atagaaaaaa
     1501 ctctataaat atattatata aaaaatctta atagataaaa tagatatgga ggaataagta
     1561 tggagcagca aaaagattac atagagttat atgaaaatga agaattaata gagataagag
     1621 aagcctgtat gaatgatttg gatacaatag caaaatttaa ttataatttg gccaaagaaa
     1681 cagaaggaaa agaacttgac atggatgttt taactaaagg tgtaaaagca ttgttattag
     1741 atgagagaaa aggaaaatat catgtatata cagtatttga taaggttgtt gcacagatta
     1801 tgtatacata tgagtggagt gattggagaa atggaaattt cctttggatt caaagtgtat
     1861 atgtagataa ggaatataga agaaaaggta tctttaatta tttatttaat tatataaaaa
     1921 atatatgtga taaagatgaa aatattgttg gaatgagatt atatgtagaa aaagaaaaca
     1981 tgagtgcaaa agcaacatat gagtctttaa acatgtacga gtgtgattat aatatgtatg
     2041 aatacgaggt aatgcgttag taatataaat ttataatatt aatattataa agtattgatt
     2101 atattgacaa ttatgtggaa taaattggat attataatta ggaattttag ggggtaaaaa
     2161 aatgggcgtt ttaaaaggaa tgttttatgt atttttattt ttagacttag tatcaatatt
     2221 ttgtttcttt tttaataaag gaaaaatagc atctaataaa attgtgttta atgcaatagg
     2281 agtacttaca tttgtacttt gttttatgct ttttagttat tatcctaata ataatcttat
     2341 tggaaaattt attgcatcta tattttttat atttggagtt gcaggagtta tgttgaaaga
     2401 aaaaaatttt ttatatgcta gactcctttt aactgtagtt attgtttttt ctacactaag
     2461 attgttcatt attcaataaa atacatttgt atgaagtttt gttaaagtct gcacatttaa
     2521 gtgtaggctt ttttgtattt ttatttagaa gttaagggaa ttttaagaaa attttaaaat
     2581 cgtcttaaat atttattggt acacttgaaa tattaataga tagaggaggc ttatcagtgg
     2641 gagaaagtaa aaagtcagag aatttgttac tgtcaattat atacataata ttttttgtat
     2701 atattttaat gattataagg ataattttat ttagagatgt accaatttat gctatttcca
     2761 agggaacatt taggactgta aatttaattc cattttatac aatatatcaa tttatagtag
     2821 atagtaatat tgactttatg aaagctacta taaatattat agaaaatata ggtatattta
     2881 ttcctatggg aattttttta cctatagtat gtaaaaatct aaataaaaaa actataatta
     2941 taacaattat acttgttagc ttagcatttg aattaacaca atatattttt gctcttggaa
     3001 gtagtgatat agatgatgtt attttaaatt cattaggtgg cataattgga attactattt
     3061 acataaacat gaataaatta tttcctaatg atattaaaag atttaaggtt ataatagcta
     3121 ctagtttaat tttaggagtt ataggattag gagttatttc taaaaattat cataacttac
     3181 taacttttaa atttagacct gataaaaaaa tatcaaaaat attaattgaa gaaaataggg
     3241 aaataattaa ggatataaat aaagatacag tagacatagt tgggacattt gagagcttta
     3301 aaaaaggaat aataactatt aaagcaggct ctaataacaa agtaaagaga ccagagaatt
     3361 taattgattc tgatggaaat ataagaattt atttaaatga aaatacaaaa ttagtatctt
     3421 atataattac caaagaatca aaaatggata tagttaaata tgaagaattt gatgtgaaga
     3481 atttagattt attaaggaga tatgatacta ttaatgtttg gattgataaa gaaaatcagc
     3541 caaaggataa acatggtatt atggctagta aattattaat tggattgtat gaataaaata
     3601 ttaaacaaga ataaaagaat aacaaatata aaaaacgaaa aaactatttc tataattatt
     3661 tttacgttgt gcataaaata agaacactgg tgaaggagta gagataaatt atggagataa
     3721 taaaatatat cttgtacttt tttatatatt catttttagg atggacagta gaaagtatag
     3781 gatgttctat agcaagcaaa agaataatca acagaggttt tttaaatggt ccaatatgcc
     3841 ctgtttatgg ttttggagcg gtaattgtga tatcactatt gggaagattt aataatgtag
     3901 taatagtatt tctattagga atgattttaa ctacaatact agaatatttt acaggattta
     3961 ttttagaaac cttatttcat gctaaatggt gggattattc tgacagaaaa ttcaatataa
     4021 agggtagagt atgtttaaaa aatgcaatat actttggtat aatgtctgtt ttaataataa
     4081 gatttataca tccatttata aaggattttg taggtataat tccatataga atattaattt
     4141 caatgtctat aattacaaca ctttgggcta tacttgattt gattgttact attataacac
     4201 ttaaaaaatt agatataaaa ttaaacttac tagacgatat aattacagac cttaatgata
     4261 taaatgtgaa attggataag tttgatagag gagaaataca agctttattt aaaacaataa
     4321 ataacgacga attagaagtt agagaaaaaa taaacaaaat aaatagtaag ctggaccgta
     4381 tagagtctaa tattatttta caaaaaagag ttataaaagc ttttccacat ataaaacata
     4441 aaaaacaaca agaacaacta gaacatttta aaaaaattat taatgagaaa aggtaattat
     4501 acaatttaat gaaaaagaat agaataatgg tatttataag atgattttca gagggctcta
     4561 taaaaataga atagagtcct ttattttttg aaaaataatg tttatttgat aaaaataaaa
     4621 tatattgttt ctgaataaca aatattttga aaattataaa aacatatatt gacaatttgt
     4681 gtcaaaaata ctaacattaa gtatataaag aattttatat gagaatatct ttataaatcg
     4741 caataatttt aaaacataaa tttatttaaa gaggggatga tttgccaatg agcgagataa
     4801 ctagtcaaat gataagtaca gaagaaaaaa aatatgttgc taaaactcaa aagatacctt
     4861 attatccagt agcatttaaa tcaggtgatg gtgcaatgct atatgattat gaaggtaatg
     4921 aatatgtaga ttttttagca agtgcaggct ctgcaaatgt aggtcatggt aataaggaaa
     4981 tctcacaagc agttaaagaa caaatggatg atataacaca atatacactt gcatatttcc
     5041 atagtgatcc tcctgtaaaa ttagctgaga agcttgtgga aatagcccct ggagataatg
     5101 ataaaaaagt actatacagt gcaactggtt ctgcttgtat agatgctgct ataaaattag
     5161 caagagggta tactggaaga acaaagataa tatctatgtg tgaatcttat catggaagca
     5221 cttatggagc catatctata tctgctttaa gtacaaatat gagaagaaaa atgggtccat
     5281 tgttaccaga agtttatcac ttccattatc ctgataaaaa tagaacagct aaagaatgtt
     5341 tagatgagat agaatatgct tttgcacact atttaccagc agaagaagta gctgcaatat
     5401 ttatagaacc aattgctgga gatgcaggaa taatagtgcc tccagtagag tgggtacaag
     5461 gtttaagtaa aatatgtaaa gaaaatggga tattacttgt aagtgatgaa atacaacaag
     5521 gtatgggaag aacaggtaag tggtttggta tagaaaattt tggtgttgaa gcagacctta
     5581 tagttcttgg aaaatctgtt ggaggtggat tacctctagg agcagttgtt ggaagaacag
     5641 aaataatgca aagtcttgat gcaccagcac atttatttac tttagctgga aatacaacag
     5701 tatgtgtggc tgctttaaaa tctatagaga taattgaaaa agaaaactta cttcaaaaga
     5761 gtatagaaat gggagattat attaaagcag gatttgaaaa actaaaagaa aaatatgata
     5821 taattggaga aataagaggt ataggattat ctataggagt tgatatagtt aaaggaaaag
     5881 gttctaatga aaaacatcca gatgctacag ctaagatatg ttatagatgt atacaaactg
     5941 gattaataat gatattctta ggacaatcta ctttaagagt gcaacctcct ctagtaataa
     6001 ctaaggagca agtagataaa gcaatgaaca tcatagattc tgcaatagat gattatttaa
     6061 atggtagaat tggtgatgaa gtatatgaag taactcaagg ttggtaaaat aaatattaaa
     6121 taaaataaga gttatctcaa ttttagaaag taatttctga aatgagataa ctcttttaag
     6181 ttacccacaa ataagaaaat tgtttgattc attaaagact acatttcgga tatcgttttt
     6241 gtgagtatta gagacagtat tgcgagaata agtaccttta ttcgtactat ctgttaattt
     6301 agttataatt aagatagcta aaagaataag aattactgtg tataaagcaa taacgtatgg
     6361 ttttctttta tatttgtatt tattattaaa aaaagaatga ccataattat ttttatttac
     6421 tttagatgta tttgtatttg tattcctttt cttgttacct ttctttttat catcctttct
     6481 tctattttta gggtaaggaa tgactttgtg tgtattatca agtttgatat ttttattttt
     6541 ttgaatattg ttttccaggc tagccttttt ttctccaaat tgaatagttt tattggtatt
     6601 gttgttatct ttcaatgtta atctccctcc cttaaacttt ccctttagat aatattacta
     6661 ctaacctatg gaatatacaa taaataatat ataagtaata aaattttata ggtataaatc
     6721 tctttctcca cgctctaatg cagtcatatt gttagatact atgtttctta tatcttctct
     6781 ttctatctta tctatttctt ctgagataag ttttttaccc ataattttaa gttcttcatc
     6841 tccataatcg attagaaatt catttaatgt agtaagagca tttggtgtac atacattatg
     6901 aatttgtcga cttttagcta agctcataaa tctatcgcca gttctaccct tgcgataaca
     6961 agctgtacaa tagctaggta tatatccatc agtaattagt tctttaagaa cctctacagg
     7021 gcttctatgg tctccaactt cgaattgttc tgtattgtca ccatcttcat atgctttata
     7081 tcccccaact cctgttagag aacctgcact aatttgtgat acaccatatt ttagtaactc
     7141 atttctcatt tcagcagttt ctctagtgga cattatgatt ccagtaaaag gaacagctaa
     7201 tctagttata gctactattt ttttgaacat atcatcagaa actaagtgag gaaaatcttc
     7261 taagctcata ccttcagctt ttttcaatct aggaaaagat atagtatgga aacctacacc
     7321 aaatttttcc tctaagtgtt cgttatgcat cataagccct agaacttcaa atttagggtc
     7381 agataaacca aataaaactc ctgcaccaac atcatcaacg ccagcttcca tagctctatc
     7441 aaaagctgtt aaatggtaat aatagtcatt ttttatagat tgaccatgca tttttataaa
     7501 tgttggtttg tgataagttt cttggaataa tatataagtt cctattcctt tttcttttag
     7561 taatttatac tcatctacac ttgtagctgc tatgttaacg tttacccttc ttatatttcc
     7621 attttcgtta tatgttgaat aaattgcatc taaacaatct aagatataat ttatatcaca
     7681 atttttaggg tcttcaccag cttctagagc aagtctttta tgacccattt tttctaatat
     7741 tttaacctct tcctttatct cttccatggt aagttttttt cttttaaatt tgttgcattt
     7801 gctaaaaccg caataaacac attcatttac acagtagttt gatacataaa gaggggcaaa
     7861 taaaaccact ctattaccat atatttcatt ttttatttgc ccagctatac taaataatct
     7921 atctagttgt tttttatctt ctacttcaag aagtgtagct atatctttat aactaagttt
     7981 ttcccttcta tcagccttat caagtacctt ttcaatatca tcagaagttg aattttttgc
     8041 atcttctaat aaagaattaa taagttcatg gtttatgaac atttacaaac gcctccattc
     8101 aatattatca ccacgagaat agtcgacttc aagtcctaat gacttgatgt tttcttctaa
     8161 gctttggtga tattcacaag cttcttgacc agtaaaggct ttgttatcgt aaagagaata
     8221 ttgttttcta aattcttgag gagaaaggtt tggcataatt acattgcaac cagctaaaag
     8281 acctgcattt ctaccactag ggtttataga tgccaaggct gttgtagcag gtaataaaac
     8341 ttttggaagt agaagtcttg taattgaaag cataagtaat gtcttttcta aatctccatg
     8401 tttataatcc ttaaatattg tatcatggtg tggaataaaa ggtcctattc caaccatatg
     8461 aggatttaac tcttttaggt ataataaatc acgcacaagg tcctcattgt tctgaaatgg
     8521 tgactcaacc ataaatccag cacctacttg ataaccaatt tccttaaggt tttttaggca
     8581 ttcttttcta gttctaagct caatgtttgg tggatgtaat tttttataat gactgtctgt
     8641 agcagtttca tgtcttaaaa gatatctatc tgcaccacat aaaaagtatt ttttatacga
     8701 atcataactc ttttctccta gtgatagagt tatggcacaa tcctcatatt tattttttat
     8761 acttgaaaca atttcacata ttttatcatc agtaaaatat gtatcctcac caccttgcaa
     8821 aacaaatgtt ctatatccta ttttataacc tatatcacaa cattcaagta tttcatcaag
     8881 tgaaagtctg tatcttatga tatttttatt agaagattgt attccacaat agtagcaatt
     8941 atttttacaa tagtttgtaa gctctataag tcctctcaag tagactctat ttccgtaatg
     9001 tttatttctc atgtcgctag cttgtttata aagatagttt cttaaatttt gttcgaagtt
     9061 atattcttca ttatcgatat tttctattaa atatagtagt tcatcaaaac ttaatgaatt
     9121 aatgctgtaa agtttatcta taaagtattt aatcttattt ttagtcatat tcaaatatgt
     9181 aattattaaa tatagttaaa tttttaataa ttgaaaagtt caagtgatct ttctaaaata
     9241 ccttttacat atgctattaa aataccatag tttacaatcg gtacattgaa agattttgcc
     9301 ttttctattc tagataacat tccagctcta ttcatcatac aagctccaca gtggactaca
     9361 agggcatatt tatttatatc ttcagtgaag gatactccag aactaaattc aaaagtaata
     9421 tttttgccag ttttctttct aatcatatta ggaattttta ccgttccaat atcatcagtt
     9481 tgtctatgat gggtacatcc ttcggccatc aagattttat caccatcttt taaagtttct
     9541 aaagcataag ctccattaat caactcttta aggtctcctt tttgtctagc aaataatata
     9601 gaaaaagatg taagaggaat atcttttggt gtatctttat ctacttgtgg aaatacttga
     9661 gagtcagtaa taacaagttt cggttttttg cctaaattag atagagtttc ttttaaacta
     9721 ttttcttttg taactataga aattgcacca ttatccaaaa tatctcttat aacttgttgt
     9781 tgaggaagta taagtctacc ttttggagct gctttatcta ttggaacaac taaaacaact
     9841 aaatcatttg gttcaattaa atccgatacc aatctgaact cagtgccatc tttaggcaaa
     9901 acccttatta tttcattttt taaattttca atcccaattt tatctgttga tgagacagaa
     9961 acaactggac atttaacctt atttttagct aagtttaaaa tttctgattg attcttaata
    10021 gtatcaattt tgttaagaat taaaatatga ggtatattct tatcattaaa cttttcaatt
    10081 agtgataaat cttcttgtga tataccaatt tggcaatcca ctactagtaa agctatatct
    10141 gtcttttcta aaacatctag tgatttactt attctaagtt caccaagttt accaacatca
    10201 tcaagaccag cagtatctat aagaacacaa ggtcctatag gaaggatttc cattggtcta
    10261 aatactgggt ctgtagtagt tccagcaata tctgatacta ttgcagcgct ttgatttgtt
    10321 atagcattta ttatgctaga tttacctgca tttcttttac caaagagacc tatatgcact
    10381 cttattgatt gtggagtaga atttagactc atttgtactc accaccttaa atttcttttt
    10441 ttgatatact agtttttaca gatacatgag gtatgttgcc caatttacca gtcaaactat
    10501 taataatatc catttcgcca acaactgcta tacatacgat tgatacacct tcttcttcgc
    10561 aaggaatgcc cattcttccc ttaataatac ctttaaaacc tgatacaacc tcattgaatt
    10621 taagctgaca ttcttttggc tcttccaaaa tagcacttat aactgcaacc tttttcataa
    10681 atatcctcct aactcagaaa atatgtctta aacaaatcca aaatcaaaaa acttttcttt
    10741 gtaaagaaaa gtttctacaa aagaaaagtt attaattaca caagtataat gtgctatatt
    10801 aaactatttc cttacagatt agataactct tttctggtag ggttagcttg taaaaattta
    10861 atttaacaac aattaactga agaatatttt tatacaattt atataaatta taataaaaat
    10921 taactaaaga a
//
LOCUS       DAMKOJ010000099        10837 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.108, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000099 DAMKOJ010000000
VERSION     DAMKOJ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10837
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.108"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            304..2538
                     /locus_tag="PC592_003067"
     CDS             304..2538
                     /locus_tag="PC592_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF4057007.1"
                     /translation="MQNHDYIKMLNKKVKLLSKELDNRNFKLKSSNEIDFFSKMPNRE
                     FMYQYIDDCISKNVHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQKLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELSTMGTTIVESARELKIQLPNEKEIYSNITFSIGGAI
                     WNGESNMTTLMLFNQVYSALKKAKSEGKNRYTLFDFKDNTFYNKLENDKEFLSEISYA
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     YLFEENCRNIRKWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLTELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKQFEKLLSKGNNSEKMFIKYSDIGKALIEKIFDGFFIMQDMKKLEANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEAAEHQ
                     KYSNFYFSANCIISENKLLLSKLHLDLINTAGYINEFESYSIPKMANTHLDESDILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMLDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLEMIDTNKIEPFLYRFIKRDGQIATVMYTQCNLSAIDGRSIAQGMYVDINKIKN
                     LTKI"
     gene            2569..3414
                     /locus_tag="PC592_003068"
     CDS             2569..3414
                     /locus_tag="PC592_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4057008.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRITFINDNLKNLIKSYMQDNPLG
                     MTNVEIAKKLPDNIAKFFTDYHNIQLNWEKDYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKSYIITMANDITKLYEENKKNLHYSITDPLTGAYNRKYLNDRFDMFIGDYIVL
                     IDLDNFKMVNDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQIEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKKKKKF
                     NKNNY"
     gene            3654..5387
                     /locus_tag="PC592_003069"
     CDS             3654..5387
                     /locus_tag="PC592_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4057009.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQYEIPSCDINNDIFEIVSEYENRCMVLGKYTVRTKENAQMIL
                     EVNQRCTFEIIEDREKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYNEFMEMSGGSAVGAVYPPD
                     LPKALEDCEQCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDMENDNFIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLRGNLHETIEIREINSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIQEYLCSSDSKNND
                     ALLIIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTYDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSVYE"
     gene            5854..6198
                     /locus_tag="PC592_003070"
     CDS             5854..6198
                     /locus_tag="PC592_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4057010.1"
                     /translation="MKNELYLICLNKRFNLWVQPTFVAPFKELLIDNNLRDIKLHKLR
                     HANATLILLSSTNIKSISEILGHADIKITMNRCSHLLYEMDNEASENTIQIMFSFTSI
                     KCQLKHFFLLIS"
     gene            6389..7744
                     /locus_tag="PC592_003071"
     CDS             6389..7744
                     /locus_tag="PC592_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4057011.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISAITNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIIFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATVIASISVFAVCI
                     AFSEPIVSLFIHPEETILFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(7862..8530)
                     /locus_tag="PC592_003072"
     CDS             complement(7862..8530)
                     /locus_tag="PC592_003072"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HDF4057012.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKDAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLVKDGYGY
                     LEIK"
     gene            complement(8597..9025)
                     /locus_tag="PC592_003073"
     CDS             complement(8597..9025)
                     /locus_tag="PC592_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF4057013.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGIFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            9137..9730
                     /locus_tag="PC592_003074"
     CDS             9137..9730
                     /locus_tag="PC592_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDF4057014.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENATKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWIL
                     IIACILLFVFPQKIQSIFSLLLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            9850..10785
                     /locus_tag="PC592_003075"
     CDS             9850..10785
                     /locus_tag="PC592_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDF4057015.1"
                     /translation="MNKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SIGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVVGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMDVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKSRNSYQGCKFV"
BASE COUNT         4110 a         1351 c         1470 g         3906 t
ORIGIN      
        1 ataaaaaact ctacattact aactatgcat ctctcaatct atctatttat gaaaaaatat
       61 gatataattg cattcaaaaa ggaaagcttt caatatacta gaatttaagc attaactaat
      121 tttatctaat attattacta ggttaaaaaa catttgtaac atttgaacaa ataacttaat
      181 gtatattaat tttaaatacg tatttaaaat taattgttta aattatttat agattaaaat
      241 ttaaatactt ctagcataaa tacagttgtc gtcaaaattt aaagtatctt atggaggaat
      301 accatgcaaa atcatgatta tataaaaatg ttaaataaaa aggtaaaact attatctaag
      361 gaattagata atagaaattt taaattaaaa tcctcaaatg aaatagattt tttttctaaa
      421 atgccaaata gagaatttat gtatcaatat attgatgact gtatttcgaa aaatgtacat
      481 ataggaatca tgttgttaaa tattgataat tttaaattat ttaatgatat atatggatat
      541 ctagtgggag aaaatttatt aattacttta actcaaaaac tattacactt tattccagaa
      601 tcaaaaggga tagttgctta tttaaaagga gaagggtttt taattgtact tccaaatgta
      661 tcaaataaag aattaagtac tatgggtaca actattgtag agagtgctag agaattgaaa
      721 atacagcttc ctaatgaaaa agaaatttac tctaatatta catttagcat tggtggtgct
      781 atctggaatg gtgaatcaaa catgactact ttaatgcttt tcaatcaagt atatagtgct
      841 ttaaaaaagg ctaaaagtga aggtaaaaat agatatactc tatttgattt caaggataat
      901 accttttaca ataaattgga gaatgataaa gaatttttat ccgaaatatc atatgcttta
      961 caaactaaac aaattgaagt attttaccaa ccactttata atataaaaaa taatactata
     1021 gttggatgtg aggctctcgc acgatggaga caccctatta aaggacttct cactccagat
     1081 aagtttattc ctttatttga acagtttggt ttgataacag aactagattt atatttattt
     1141 gaagagaact gtagaaatat aagaaaatgg attgataaca atgatgtttt tgttccaatt
     1201 tgttgtaact tttctcgtct tcattttttt aatcctaatt ttccaagtat gctaaaaggt
     1261 attactgaaa agtacagcgt ctctacatca aatttcagca ttgaaataac agaaaatata
     1321 ttaatagaaa atacaaatac aattattcaa caactaactg aacttcgttc ctatggtttt
     1381 tctgtatcaa tggacgattt tggttctgga tattcatctt ttggtatgtt gcaaaatctg
     1441 ccttttgata taatcaaaat tgatagaata tttttatctc ataatttaaa tgattttaaa
     1501 aatacaacca ttttgtattc tataataaac attgcaagag ctcttgggat gcttacagta
     1561 tgtgaaggtg ttgaaacaga acaacatgta gaatttatta aaagtataaa ttgtgatata
     1621 gctcaaggtt attattatgc aaaacctatg gagtgcaaac aatttgaaaa gttactatct
     1681 aaaggtaata attcagagaa aatgtttata aaatattctg atataggaaa agctttaata
     1741 gagaagatat ttgatggatt ttttattatg caagatatga aaaaactaga agcaaatgtt
     1801 actgaagaca ttcaatggtt tgatttttac aacaaaactg aaattacatc ttttcctaaa
     1861 gtaatagaac attttgaaaa acacattaaa ggtaaaaaat tttctatcct ttacaaaagt
     1921 ataaccccac ataatactga atcagattca ttattgatta gtggagaagc tgttttatca
     1981 gacgaagctg ctgaacatca aaaatatagt aacttctact ttagtgcaaa ctgtataatt
     2041 tcagaaaata aattactctt atcaaaatta catctggatt taattaatac tgctggctat
     2101 ataaatgaat ttgaatcata ttcaatacct aaaatggcaa atacacatct tgatgaaagt
     2161 gatattttat cacaatttta ttcaatgttg cctgtaggta taattcgata cgatttattt
     2221 ggtgatatga ttattactta tatgaatgaa gaaatgcttg atattatagg ttatacaaaa
     2281 gaacagtttt ttggtgagat gggcggaaat ttaagagcaa ttgttcatcc agatgattta
     2341 gactttgttt ataaaaaaag tttggaaatg attgacacaa ataaaattga accattctta
     2401 tatagattca taaaacgaga tggtcaaatt gccacagtta tgtatacaca atgtaacctt
     2461 tctgcaattg atggaaggtc gattgctcaa ggtatgtatg tagatataaa taaaataaaa
     2521 aatttaacaa aaatctagta caaagtattt tattttggag aaattaatat gtttaaagaa
     2581 atttttttaa gaacttttcc aggatttcta attataagag attctaacta tagaattaca
     2641 tttataaatg ataatttaaa aaatttaatt aaaagttata tgcaagataa tccacttgga
     2701 atgactaatg tagaaatagc taaaaaactc cctgataata ttgccaaatt ttttacggat
     2761 tatcacaata ttcaattaaa ttgggaaaaa gattatcctt atgataaaat atcaaattgg
     2821 attttagaat ttaaaaaaga tactacaagt tattggaatg ttttagaata caaagtagat
     2881 gttgatgaaa aatcctacat aattactatg gccaatgata taacaaaact gtatgaagaa
     2941 aataagaaaa atcttcacta ctcaattact gacccattaa ctggagcata taatagaaaa
     3001 tatttaaatg atagatttga tatgtttata ggagattata ttgtactaat tgacttagat
     3061 aattttaaaa tggtaaatga ttatgaaggt cataatgtag gagacaagat tttatgtgat
     3121 tttgtttcac ttttaaataa agaattgata aattctactt ctattataag attaggagga
     3181 gatgaattta ttgttatatt ctctagtgat gttgacaaaa attatgttta ttcacagata
     3241 gaagccttaa gagaaaattt tttaaaagta ttctctaagt ataagtatct ttcatttagt
     3301 tatggtgttg atacagtaaa aagaaattta aaattgacaa tagttgaatt ggataaaaaa
     3361 atgtataaaa acaaggaaaa aaagaagaaa aaatttaata aaaataatta ttagcattgt
     3421 cattttaaaa taaattaaaa ttagctttct tttttaaaac ttttacctta gcttataaat
     3481 atgtatctat acaaggtatt aatattaaat actgaaacat atattgtttc agttcttttt
     3541 tgttaaaatt aacttattca ataaagatat catagttcaa caaagctttt aatttaaata
     3601 tattgatgta taatataatt aaaatataat agcaaaaaga aaggaggaat atcatgagca
     3661 tactcctaaa aaaagcaccc aaattagcaa aacatattat aacaagtttt tatataaatc
     3721 gagatattga tgaagtatta aaataccttt gtgaaaatgt tacatggatt ggaccaggag
     3781 aacaggaatt tctcacttct tttaatgaaa taaaaaatta tttttatgca ggtcaatatg
     3841 aaattccttc ttgcgatata aataatgata tatttgaaat tgtaagcgaa tatgaaaata
     3901 gatgtatggt attaggaaaa tatactgttc gaactaaaga aaatgctcaa atgattttag
     3961 aggtaaatca acgttgtaca tttgagataa ttgaggatag agaaaaatta ttagtaaaac
     4021 acatgcacat atcaaaccct tatggtgaaa tgcaacttga tgaatacttt cccactaaaa
     4081 ttggaactca aagttatgat tatttgcaaa gattactaaa ggaaaaaaca gaagttattg
     4141 aaatgattac aaataatatt aatggtggct taaaaggtag caatgatgat agtacatact
     4201 catttttcta tgtcaatgaa ggattgccca agatattagg atacacgtat aacgagttca
     4261 tggaaatgag tggtggttca gcggtaggtg ctgtatatcc accagactta cctaaagcac
     4321 tagaagattg cgaacaatgt tttgcaaaag gacctacata ttcatctgaa tatagaatac
     4381 gaaaaaaaga tggaacatta atgtgggtat tagattctgg aatgaaatca ttaaatagtg
     4441 atggcatagt aaaaattaat agtattatta ctgacataac ccaactaaaa aacatagaat
     4501 ctgaactaaa attagaaaga gaacgatatc gtattgcttt gcaaaatatt acagatatca
     4561 tgtttgagta tgacatggaa aacgataact ttataaaata tcaacgtgta gaaattgaca
     4621 aaaaaattga attggaaaat tttgaaacaa aaaattactc taagctatta gaatctggta
     4681 aaattattca ccttgatgat attggaaaac tactagaagt acttcgtgga aatcttcatg
     4741 aaacaattga gataagagaa ataaattcat taactaaaaa tgaatggaga tggattcgtg
     4801 ttcaatgttc agttatatat gatagtgacc ataaccccat caaaacaata ggcgttttaa
     4861 aagacataac tgaagataaa tctaaattag aaagcttaat taatcaggct caacgcgacc
     4921 cactaacaca attgtataat caaagagtat cacaaaatct tattcaagag tatctgtgta
     4981 gttctgattc caaaaataat gatgctctat taattattga tattgatgat tttaaaactg
     5041 ttaatgatac ttttggtcat ttagagggaa atgaagttct agttgctgta tcaaaaatac
     5101 tattacataa cacatatgat aaagacatag ttgctcgcat cggtggagat gagtttacaa
     5161 tatttataaa atcattaaca aaggatttaa taataaaaat tactaatgat attttaaatg
     5221 atgcaagtaa aataaaagta aaggacaatc ataaaataac attaagcatt ggtattgctt
     5281 ttactgatga ttcaactaaa ttatataaag atttattttc taaagctgat aaagctcttt
     5341 atttatcaaa agcagatggg aaaaattgtt atagtgtgta cgaataaagc catttatatg
     5401 gctaaaaatg aacctttaaa ttcaaattca tagtctaaca atcaaagagt caaagctaat
     5461 cttatagata gccaactagt tactagaaaa aatttaggca ctatatttat tgatactgct
     5521 catttttcca aagagcaaat ttatataaaa aattaaactt ttatgtatgc acaaatacta
     5581 atgataaaca ttttgttaca aacatttatc attagtatgt tctatcttaa aacaaaatga
     5641 taatttatct atataaaaaa gtgctttgtt gacagagttc acttttttat atagatagtt
     5701 taaatatgaa tacatgtttt atcccataca ttttggttaa tataaaacct tgtatcttat
     5761 tatattcatt catctgttct taaaatttac ataccacata gctaatataa aactaaaatc
     5821 acccctttaa ttaactcact ttctacatgt atattgaaaa atgaattata tttaatatgc
     5881 ttaaataaaa gattcaacct atgggttcaa ccaacttttg ttgctccttt taaggaacta
     5941 ttaatagata acaatcttag ggatataaaa ttacataaat taagacatgc aaatgcaact
     6001 ttaatattac tttcaagtac taacataaaa tctatttctg aaatattagg acatgcagat
     6061 ataaaaataa ctatgaatag atgttctcat ttattatatg aaatggataa tgaagcatct
     6121 gaaaatacta ttcaaataat gttcagtttt acatcaatta aatgtcagtt aaagcacttt
     6181 tttctactta tcagttaaat gtcagtaata tatatagtaa gatatactta taaaacgttt
     6241 gaaatcacta ttccttaata aatgttataa ttatttacta tttgctgttg acattggtat
     6301 tataccatag tttatcattt atattagaaa ttaaattatt aattaatagt ttcgtaattt
     6361 tacaacagat ttacagggag tgataataat ggatacaaaa atatctataa acgaaaacat
     6421 gagtctaggt aaaagatttt ttaaatacct agcaccatct gtagttgcaa tgtgggtttt
     6481 ctcactatat acaatggttg atggaatatt tgtaagtaaa ggagttggag aattagcttt
     6541 agctgctgtc aatatatcaa tgccttttat taattttata tttgcagttt ctctattatt
     6601 ttcaactgga gcatctacta taattgcaat ttatcttggg aaaaaagata ttaagtctgc
     6661 taacgaagtc ttttcattta acttagtatc aataattata ttatcaataa ttatattagc
     6721 tataactttt tttaatttag acagattagc actattttta ggtgctacag aatctacaat
     6781 tggtatggtt aaagattatt taggaataat aatatttttt aacggattct ttatagtgtc
     6841 ttattcttta gaagttataa taaaaactga tggctttcca atattagcta ctgttggtgt
     6901 aataatatct gctattacaa acatcatact tgattacttg tttgtaattg aatttggatg
     6961 gggtgtaaaa ggtgctggta ttgcaactgg tttgtctcaa gtcttttcta ctattttctt
     7021 cttaatacat tttttaagaa aaaactctac tttgaatttt tcaaaattta gaattgattt
     7081 taagacactt agaaaaatta tatttatagg ttttcctgat tcaactactg aattaagctg
     7141 tggtatagtt gtcttacttt ttaacttaag tcttactaaa tatattggag aaaatgctct
     7201 tatttattat agtgtcataa attatataaa tacattagta cttatgacta tgatgggtat
     7261 aactcaaggt atgcaaccac ttactagttt ttattatggt gcaggaaata tagataatgt
     7321 aaaaaaacta ttaaaaatgg ggataaaagc cacagtaata gcatcaattt ctgtatttgc
     7381 agtttgtatt gctttctcag aaccaatagt ctctttattt atacacccag aagaaacaat
     7441 tctattcaat gaaggagttc gtgtctttaa aatattctct atatctttct tattggtagg
     7501 aattaatgta ataatttctg gattctttgt atcagtagaa aaaccatcaa tttctactgt
     7561 tatatctctt ggtagagggc ttgtaatagt tgttttaagt ctaatttcaa tgatactaat
     7621 atttggtggt caaggaatat ggatgactac tattgtttct gagtttatat gtcttatttt
     7681 atcattagtt tttttaaaaa agaatttttc tacattagac tctaatctaa ataaggttgc
     7741 atagatgata agagtggcaa tatatgaaaa tatataaata aaaaatacct attatacaat
     7801 cttgcaaaca ttaaaccttt gcaaatatta ggattatata ataggtattt tatttatgta
     7861 attattttat ttctaaatat ccataaccat cttttactaa agttcctttt acttcatatt
     7921 ctacaggttt tttaaatatt ggaccgtcta cgacaaatgt atgatactct ccatgttctc
     7981 cacatgggtc tgcaccagca tcttttatct tctccacaag ttctctagtt aatttttttc
     8041 ctaaaaattc ttctcctaga tgctttaagt ttacttttgt tacaacacta caaaatccac
     8101 tgtctataaa ttcatatact aaatcctctc tactctcttg ccataatggt aaatctactt
     8161 tcataccaac tgcttcacat ctatcagtat cccattttct atggctttct atatctatat
     8221 ctccatatgc gcatattgtt gctcccatgt ttttagcttt tattaaagcc ctctcaaaac
     8281 tctcttcata tccttctact ccacactcag caactaataa aggtaatcct atattgctac
     8341 ttacttgttt aagcatatta tattctaaat tatgtgtcca tgattttcca tgttcttcac
     8401 ttatagttgt caagagtgcc acaggcttat atcctttttt caacattcta tttaatgcta
     8461 atatactatc tttaccacca ctaaatgaca ttacaaattt ttcatcagcc aattttaaca
     8521 cctctttcat ctaactttgt tttattaaca taattatacc aaatttttga gttgcatagc
     8581 aaattatatt aaattgttaa ttcactataa aaaatgttcc taatatcaaa agtataaccc
     8641 ctatgtattt gtataaatgc attgtttctt gtcccaaaat tacgctatca ataaaaaatc
     8701 caactaaaac ttgggacaca agtgttaata taagtgtatt tgatactcct aaatttggaa
     8761 ttgcctttac agtaaaatat attattagac ctccaaatat tcctcctaat aacaacttat
     8821 aattaaaacc atttatagat actaggcact ttaggtcacc tgtaactatt atacttgcca
     8881 aaaaaaatat tgctcctaca gttaaactta taaatgtggc cactaatgct gttgtacttt
     8941 ttcctagctc tccatttata aaagcttcaa gagctgtcga accacctgct aataatgcaa
     9001 atattattgc ccataatttt gtcatggaca aacctccttc tatataattc tattatatta
     9061 atagaagttt atgatacaac ctattaatta attactaagt atagtttaat ttttatacac
     9121 taggctttat ttggatatga atttctgtta taattgttct atcgattttg gaggtgattt
     9181 tatgtacaca aattttaata tcgattttaa taattttaat aaaaaagaaa atgctactaa
     9241 atttatgtta atgggagtat tactcattat attaggatta ttatgcctta catttaagac
     9301 attaggtata aaattaattt cttggacttt tggtattgca cttttattct ttgcatattt
     9361 aaatttaaaa aatattaatg aactaaaaag atatgctact aaagaagaaa ttaaaccctc
     9421 tattaatatt caatggattc taataattgc atgtatatta ctttttgtat ttcctcaaaa
     9481 aatacaaagc atattttcat tattattagg attttattta atctttaatc aactagtagc
     9541 acttgtaaat agcaagaata atccttattc taaatttaca acttggaata tagttaagat
     9601 tctatttggt atatgcctta tattatctcc acttttttta tctagattta tagtgtcgat
     9661 aatgtctttt ttcataatat tatttggact agttctattc ttctctggaa atactgcgag
     9721 aaaatattaa ttattttctc gcagtatttt tatattgctt aaaatagaat ttgtttaagt
     9781 tatttattta tggtaatatg ttttttgtac aatctcattg tacaatttta ttagaaatag
     9841 gtgatttttt tgaataaatt taaatatgct tttgataata aaaggtatca tacttggaat
     9901 tactatctta gaaatacttt tggagaaaaa gtttttaagg tatctataaa tgcaggattt
     9961 acttgcccaa acattgatgg aagtattggt tatggtggat gcacatattg tagcaaagaa
    10021 ggttcgggtg attttgctgg aaatcctaaa gataatctta tcagtcagtt ttataatata
    10081 aaagaaatga tgttaaaaaa atggcctcat gcaaaatata ttggctactt tcaagcctat
    10141 acaaatacgt atgctcctct tgaagtttta aaagaaaaat atgagactat attagaactt
    10201 gaagatgtag taggtctttc aatatctaca agacctgact gtttaccaga tgatgttgta
    10261 gaatacttat ctgaactaaa taaaagaaca aacttatggg ttgaacttgg acttcaaaca
    10321 attcatgatt ccacatctaa aattataaat agaggtcatg attataaaac atttgttgaa
    10381 ggtgttgaaa aattaaagtc taaaaatata aaggttgttg tacacattat aaatggtctc
    10441 cctggtgaag attataatat gatgatggaa acagcaaagg cagttggtaa aatggatgta
    10501 gacggcataa aaatccatct attacatgtt ataaaagata ctcctatgga aaagatgtta
    10561 caaaatggta tgttaactct tatggaacaa gatgaatata tcaatcttgt ctgcgaccaa
    10621 ttagaaatac ttcctgaaac tatgataatc catagactca ctggtgatgg taaaagggat
    10681 gaattagtag gtcctatatg gagcctaaaa aaatgggaaa ttttaaatca aattgatgac
    10741 accttaaaat ctagaaattc ttatcagggt tgtaagtttg tttaatacta aataattatt
    10801 acaaataaaa caatatctac aaaataataa ctataga
//
LOCUS       DAMKOJ010000100        10833 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.109, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000100 DAMKOJ010000000
VERSION     DAMKOJ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10833
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.109"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(197..1141)
                     /locus_tag="PC592_003076"
     CDS             complement(197..1141)
                     /locus_tag="PC592_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF4057016.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLASEQVAFTRLF
                     FGFIVLGIYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIVGVSIAAVL
                     LYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGI
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSKPWEILNYANNLDVLFC
                     MLMLGIVPAALAYIFYATGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSSKLKQIEKTESI"
     gene            1459..2901
                     /locus_tag="PC592_003077"
     CDS             1459..2901
                     /locus_tag="PC592_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4057017.1"
                     /translation="MNLNLELDLEFYKKILEASHDEICVSDDKGIIIYCNKAFEENYG
                     LKKEDILGKNVSFLEDSGYSTKSPIPVVLKTKSKFSLEQDTQTGKKLIITATPIFDEN
                     GNLEFTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVM
                     RPIINTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRANGPFITINCATISPQLL
                     ESELFGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFT
                     PVGSLKNKNVDIRIISATNADLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVE
                     IIKYYFNRYSSDFNLNKTISKEAMETIANYRFPGNIRELQNIIQKILLTCTDNHITIH
                     NLPNILTKNINITNNGNKTHISQINKVITPDSKSINYKNKNFDTLIKEYEKNIILDAY
                     EKFGSSYKVAKHLEISQSKANRLIRKYTNT"
     gene            3101..3685
                     /locus_tag="PC592_003078"
     CDS             3101..3685
                     /locus_tag="PC592_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HDF4057018.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(3779..4558)
                     /locus_tag="PC592_003079"
     CDS             complement(3779..4558)
                     /locus_tag="PC592_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF4057019.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDMVAIEEIEKKGVQFNVATGRI
                     FKQARNIIEESLDMNGYYICENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(4616..5872)
                     /locus_tag="PC592_003080"
     CDS             complement(4616..5872)
                     /locus_tag="PC592_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDF4057020.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFAESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILRKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEGEAFKLIKPVEEKIKSRVGKYVYTEGDISVSEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVAYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVRKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            6130..7029
                     /locus_tag="PC592_003081"
     CDS             6130..7029
                     /locus_tag="PC592_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF4057021.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVGEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            7053..8501
                     /gene="ddlR"
                     /locus_tag="PC592_003082"
     CDS             7053..8501
                     /gene="ddlR"
                     /locus_tag="PC592_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HDF4057022.1"
                     /translation="MIFSNLKLNDNEPIYIQIKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSDGLIYSISGKGTFVKSKNKSSNTTWSLNWDYLENTYSKK
                     ASELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLKYMTNKGVDISNKDILITNGFTEGFDIVMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFDMLEYNLIKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYECVKKHIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            8560..9366
                     /locus_tag="PC592_003083"
     CDS             8560..9366
                     /locus_tag="PC592_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF4057023.1"
                     /translation="MNLILGDNMSKKSKRKKINKLKLTIVITLLFLALLSIYEILFSN
                     PNKKDNVKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     INLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVISNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIRKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            9392..10576
                     /locus_tag="PC592_003084"
                     /pseudo
     CDS             9392..10576
                     /locus_tag="PC592_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
BASE COUNT         4149 a         1541 c         1467 g         3676 t
ORIGIN      
        1 aatattaatt tgtatattta cacaataata ataaaaaata gataatctaa actgtagata
       61 cttatatttt atttgtattg tccactttat tctataaact ttataaacag ttattttttt
      121 atactaaata taatttggta taatttttgt tagactctac agtgtatacc aataaataat
      181 ttttaagtat ctagttctaa atactttcag ttttttcaat ctgctttaac ttgctagact
      241 tataaaatat tcttatttca tcataagaaa gattaagtgc tactactgca gatatcaaca
      301 tcaacatcac tccaaataac tttcctaagg aaaaactttc tcctaatata gtgcaaccaa
      361 ttattactga accaaccaac tctactgatg ccacaacacc tgcaacggat aactctactc
      421 ctttagagat acctgttgcg taaaaaatat atgcaagtgc agctggaaca atacctaaca
      481 ttaacataca aaataaaaca tctaaattat tagcataatt caatatttcc caaggttttg
      541 aagaaggaat cataaatata gctccaaata agaaactgta tactaatatt gttgaacttg
      601 aaaattcctt taaagcattt ttactaatag tcggcataag tgcatatgct attgctgata
      661 atatcccaag taaaagtcca aaagcgttta aaccttgaaa atccaaacgt ccaccagtca
      721 ctgccataat ggcgccaata aaacaaagaa taagtgaaaa taatttactt ctagtaatat
      781 tttctttata acatactttt gagaatattg ctaaaaacaa tggtgatgta tatagtaaaa
      841 ctgctgcaat tgatacacct acaatgtcaa ttgctttaaa ataacataaa ttaaacattg
      901 cctgacatat aatacctatt attactgaat atataattcc ttttttgctt atttttaaga
      961 tttgtggtgt tcttatagat gaatatattc ctaaaactat aaatccaaaa aataatcttg
     1021 taaatgccac ttgttctgat gccaatccat ttcccattaa aaactttcca aataatccaa
     1081 gtgtagccca taataaccct gctattgcta taaatacata ccctttactt ttttctccca
     1141 ttttaagttc ccttctattt ttatttagtc aatttacact attcttttta agcaaaattt
     1201 atgccatctt aaaccaatat attccgactc taaaacccta gtctttccaa caatactaat
     1261 aaaacttcaa tttttttata tttatttttc acttacttta agttgattta gacttatttt
     1321 aattgtaaaa tgagttatat ataacttatt taaagttaaa atagactgaa atttatatat
     1381 aaatgtcaaa ttttaagtat attaatcaat taaacttatt ttaatatatc attaaaaggt
     1441 taggaggaaa atagaaaaat gaatttaaat ttagaattag atttggaatt ttacaaaaaa
     1501 atattagaag cttcccacga cgaaatatgt gtctctgatg ataaaggaat aataatatat
     1561 tgtaataaag catttgaaga aaattatggt ctgaaaaaag aagatatttt aggaaaaaat
     1621 gtttcttttt tagaagactc tggatattca acaaaaagcc ccataccagt tgtattaaaa
     1681 acaaaatcta aattttcact agaacaagat actcagacag gaaaaaagct catcataact
     1741 gctaccccta tatttgatga aaatggaaac ttagaattta ctgttgaaaa ttgtagagat
     1801 ataactgaac ttaataatat aaaaaataaa cttgaagaca caaaaaaaca agtaaaaaaa
     1861 tataaatctg aagtagaaac actatacaga actgctctta gaattgaaga tactgtaatt
     1921 atggatggaa tagttatgag accaatcata aacacagtaa atcatgtttc taaaacggat
     1981 gtaagtgtac ttttattggg tgaatctgga acaggaaaaa gctcacttgc tagatatata
     2041 caccacaaca gcaatagagc taatggacca tttataacaa taaattgtgc aactatatct
     2101 ccacaacttc ttgaatctga actttttgga tatacttcag gtgcttttac aggtgcaagt
     2161 actaaaggta aagttggtct cgtagaatta gctaatggag gaactctttt tttagatgaa
     2221 ataggagata taccacaaaa tctacaggca aaatttttgc aattaataca ggatagaact
     2281 tttactccag ttgggagttt aaaaaacaaa aatgtcgata taaggattat atctgctaca
     2341 aatgctgatt tagtttcaaa agtaaaagaa aaaaaattta gagaagattt atactataga
     2401 ttaaacgtta tagaaataaa attgcctcct cttagagaaa gaagagataa tctagtggaa
     2461 attataaaat attattttaa tagatactca agtgacttca acctaaataa aactatttcc
     2521 aaagaagcta tggagactat tgcaaattat agattcccag gtaatataag agaattacaa
     2581 aatataattc aaaaaatttt acttacttgt acagataatc atataacaat acataactta
     2641 ccaaacattc ttacaaaaaa tataaatatc accaataatg gaaataaaac acatatatca
     2701 caaattaata aagttattac acctgactca aaatctatta attataaaaa taaaaatttt
     2761 gataccttaa ttaaagagta cgaaaaaaat ataattttgg atgcttatga aaaatttggt
     2821 agttcttata aagtagccaa acaccttgaa atttcacaat ctaaagccaa taggttgatt
     2881 agaaagtata ctaatactta attttaaatt tgataaataa aaacttaaca ctatttacat
     2941 attgtaaatt tggctattta ttggtattat gaatatggtt gaaattattt aaataaatcc
     3001 tattgactta gtttcatata tttaccatta aacttttatc ataaatatca tatcataata
     3061 atatatttaa taagtctaat aaactatacg aggtgtaaat atgttaatga atacccattt
     3121 tattatggca aaatcaatac ttgataatat agatgaaaat aaaacattct ttataagcga
     3181 aaaaaatttt atatatggta atataaagcc tgatgctttt tctaaatata aattaaaaaa
     3241 acattattta gatgagtcat ttaatatgat tgtttctaaa ataaactatc tatgtagtct
     3301 taatatagat agtctttcta aatacttttc agtaagtaga cttagtcagg aactaggagt
     3361 catatgccat tttttatgtg attttttctg tgtagctcac agtgaacgtt gggaatttaa
     3421 acacagttta aataaacatg ttacttatga aagagaactt ggagcatttg caaaagatgt
     3481 tgatttatct aaaattaaat gtggtactat aaatagtagc tttgagaagt tttttactaa
     3541 actttatagt gactacaaaa agaaaactga ttatatgaat gatttaaaat tttcagctta
     3601 tacttgtaat agtgtcataa attatatact tgactctatc ttgtctaata caataaaatc
     3661 atatcatata gcaaattgtg gttaatttaa gaatttttaa acttacaatt gaatataatt
     3721 aaaatgactg ctctatagaa tataatttta taattctcta gaacagtcat tttttatatt
     3781 aactatttat ctccattata acatctatag cactttttac actatctact acataatttg
     3841 cactttgctt tacatcttcc cttgccttag acattgcaaa actatattta aatccttcta
     3901 acatacaaat atcatttgga gaatccccaa tagtagcaac ttcatctgga cttacattta
     3961 aagtttttat tacatgctct atacttcccc tttttgacac acttttagga actatattta
     4021 aagtatatgt tccagaaaaa tatatttcta atacttcact aaactcgctt tttagataaa
     4081 gttctattct ggataattcc tccaaatttt cagaacatac tcctatattt cctataaggt
     4141 tatcaaaact acttcttttt tcaaaatctg ggtcaactat aaaatcacta gaataatgtc
     4201 taaaagcagt ggtatcacta cccacaatta catcaccctt atatttaaaa taaagttgtg
     4261 catcacttga ctcaaatcta tcaatgactt ttttaactaa attatcatct atcgttcttt
     4321 taaaaataac attataatct ttatcatata taaatgaacc attttcacat atataatatc
     4381 cattcatatc taaactctct tcgataatat tacgagcttg tttaaaaatt ctacctgtag
     4441 caacattaaa ctgtactcct tttttttcta tttcttcaat tgctaccatg tcctcttttg
     4501 ttatagttcc attttcatat aaagttccat ctaaatcaca aaatatatgt tttatcataa
     4561 attaaaagcc tccaaaaaca attttatatt atactaatat tttaatcaaa ataacttaaa
     4621 gcttttctaa ttgtattctc aattcgttaa gtaaatctct agtagctctt aatcttatct
     4681 ttcttctatc tccattaaat atatttttcc ttactattgt ttttccattt atatatattg
     4741 cagtataaac tagtcctaca ggcttctctt tagttcctcc accaggtcca gctactccag
     4801 ttgtagatat acctatatta gctttaagtc ctttagcaac gccctcagcc atttctattg
     4861 ctgtttgctc acttactgct ccaaactctt ccaaagtttc tctttttact cctagtcttt
     4921 tcattttaga atcattagaa tatgctacac aaccttcaag aaatacagag gatatacctg
     4981 gatagtttat aagagatgaa gaaaccaaac ctccagtaca agattcagcc actgctattg
     5041 ttagattttt ttctacgagt aacttagaaa cagcatcttc taatgcagtc tccccttctg
     5101 atactgaaat atctccttca gtatatacat atttgccaac tctgcttttt attttttctt
     5161 ctactggttt tattaattta aaggcttctc cttcattttc agcctttgca gttattctta
     5221 ttgtaacttc taattctttt gcatataaag caactgttgg attagtctgc tcattaatta
     5281 tatcgagaat ttctaattct agatttgact cacctattcc atataatctt aaagtcttag
     5341 atactagcat ttcatttgta aattgttgta agtaaggttt gacactctca ttaaacatag
     5401 ctttcatttc tcttggaggt ccaggtaata ctattataaa tttgccatct tttcttaaaa
     5461 ttgcccctgg tgctgtacca ttattatttt ttagtactat agcatctttt ggaaagtaca
     5521 cttgtttcat attattttcg gccatttttt ttcctgtttt aacaaagaaa gattccaaaa
     5581 cctctagtga tggtttatgt agttctaatt tctgaccaaa gtattctgcc gcagtttctt
     5641 ttgtcatatc atctccagtt ggtccaagac cacctgtagt aattacaaaa tcacttctct
     5701 ttaggctttc agcaaaacat tctaaaagtc tttgtttatt atctccaaca gtactctgat
     5761 ggtatacttc tattcccaat gatgcaagtt ctttagctaa aaattgagaa tttgtattta
     5821 ctatatctcc taataatatt tctgttccta cacttattat ttcagccttc aaaatttatc
     5881 actccttgat ttatagccat taagactagt cttaagttca taacaataat tttagcaaaa
     5941 ataataacat aaataaagtt aaaaaatcat ttaaacatat ctttaaacta gagtactgct
     6001 ctaaaaccac acataataca aacttcgtat atagtggtac tttcatcgtc aactgttaat
     6061 tcatataatt aagtatgtaa ataaaaaatt tactttaaaa taataaaaat caaaatagga
     6121 gtgtataata tgaaaatagc agttataatg ggtggaatat catcagagag agaagtttct
     6181 ttaaattcag gaaaagagat atataataac cttgataaaa ataaatacga agttgtaaaa
     6241 gtaattatag atgataaaaa agatatattt acaaagatac cagaagatat agattttgca
     6301 atacttgctt tacatggaaa atttggtgaa gatggatgta tacaatcaat acttgaaact
     6361 atggatatac catattctgg atgtggacct ctttgcagtg ggatgtgcat ggataaaaac
     6421 ataactaaaa aaatgcttag agattcaaat ctacctactg ctccatgggt tctagtaaaa
     6481 tcagttgatg aaatagacta tgatgaaata gataatatag gctacccagt atttataaaa
     6541 ccaaactcag gaggttcaag tgtagccaca ttctttattc attctaagga tgaagttgga
     6601 gaagcagtta gaaaaggtct ggaagttgat gaatttgtaa tgattgaaaa atatatacca
     6661 ggtggagaat atacttcatt catattaaat ggagaagtat tccctacaat ctctataaaa
     6721 tctgattcag gattctttga ttatgaagct aaatactcag ttgaaaaagg tgcaaaagag
     6781 gaagttgttt acttagatga agaacttcaa aaaagagtaa acgaaatttc tgagacttgt
     6841 tggaaaattt ttaattgcaa agcatatgta agagttgata tgattataag tgaaggtatt
     6901 ccatatgttc ttgaactaaa tactcttcct ggaatgactc aaactagttt aattcctaga
     6961 agtgctgctg ctagaggtat taagtacagt gaactattag ataaacttat agaatactct
     7021 ttaaattaga tgaaataatt tgaggtggta atttgatatt ttcaaatcta aaattaaatg
     7081 ataatgaacc aatttatata caaattaaaa attatataag tgatatgata tcaaaaggac
     7141 taattccaga caatagtaag ctcccttcta caagggagct tagtcagctt ttacaagtta
     7201 gccgaaattc tgtagttttg acttatgaag aattaaaatc agacggatta atctactcta
     7261 tttcaggaaa aggtacattt gttaaatcaa agaataagtc ttcaaatact acatggtcat
     7321 taaactggga ttatttagag aatacatact ctaaaaaagc cagtgaattg gatattataa
     7381 aaagtgaaat tccttggagt tctgacctaa tttcctttaa aagtatttct ccagacggag
     7441 atttattcga catggaagaa ttaaaaaaat cctttttaaa tagaatttca ctagaaggac
     7501 ataaattact caactatgga tatgcacaag gttataagcc ccttattgac tatttactaa
     7561 agtatatgac aaacaagggt gttgatataa gtaataaaga tatattaata acaaatggat
     7621 tcacagaggg ttttgatatt gttatgtcat cttttaccca agaaaaagac tacataatat
     7681 gtgaaaatcc tactcataat acagctataa aaatcatgaa atctcataat ctcaatatct
     7741 taggtgtaga tataaatgaa gatggtttgg acttcgatat gctagaatac aacttaatta
     7801 agtacaaaaa taaaataaag tttgcataca ttacaccctc ttatcacaat cctacaggga
     7861 ttgtaatgac tcctgaaaat agatacaaat tttataatct tatgaaaaaa tacaatatag
     7921 caattataga ggatggattt aatgaagaat tactctacaa tagctctcat atatttccta
     7981 tctgttccct agataatatg aataatggcg ttgtatatat tggtagtttt tcaaaaattt
     8041 tatttcctgg aatgagaatt ggatggatat ttgcagataa aaaagtaatc aataagctag
     8101 aaagtgtaaa aaggtgtaga aacatacacg tatccttttt agaccaagga attttatttg
     8161 attacttaag taatggaggt tttgaaaaat acattaaaaa aatacgtaaa ttctatggag
     8221 acaaatttaa ctttgcatat gaatgtgtaa aaaaacatat aaaaacagaa tacatcttgg
     8281 gtgatggtgg tttgcatata tttataaaac taaaaaatat agatactaga gttctattag
     8341 aaaaatgtta tgaaaaaaat gttatattta tgcctggaga tttatttttt acagataact
     8401 ctggttttga tactttaaga cttggatttt ctaggttgtc tttcgaagac attgaaattg
     8461 gaataaaaat aattggagaa actataaatg aaatgttcta ggttaactaa atattgttag
     8521 cctagtttat ttttatgatg tataatatat atagtttata tgaatctaat actgggggat
     8581 aatatgagta aaaaatcaaa acgaaaaaaa attaataaat taaaattaac gattgtaata
     8641 actttattat ttcttgcttt attatctata tatgagatac tattctctaa tcccaacaaa
     8701 aaagataatg taaagagcca agaaactatg caaaataaaa ataatacaac agatgattct
     8761 aaaaataatc aaagctctac caaaaagcag gaagataaca atatcaagcc tactttttca
     8821 tattcttcaa taccagataa tataaaaaat aaaatgattg gtaaatctat gcctactgat
     8881 gagcctataa gctttgatag tctatcttat ttaaaactta catactatgg atttgatgaa
     8941 aaaactcatc aaggagaaat gatagtaaac agtgagctag ctccagaagt agtggatatt
     9001 tttaaggaat tatacgaaaa aaaatatcca attgaaaaaa tcaatctaat agatgactat
     9061 gatgctgtag atgagaaatc tatgtctgat aataatacct catcattttg ttatagaact
     9121 atagctggta caaatgtcat ttcaaatcat ggtaaaggtc gtgctataga tataaaccca
     9181 ttacagaatc cccaagtttc tggaaatgat gttactccta aagtaagtac agtttatgct
     9241 gataggtcta gcacaaaatt tggaatgata agaaaaggtg atgattgtta taatgctttt
     9301 gtaagcagag gttggagttg gggtggatat tggaaaaacc cagattatca acattttgaa
     9361 aaataataga ttagaaataa aggtgaatta tatgaattta atgacattgg aaaacataag
     9421 taaaagctat tctgaaaaaa aattacttga aaatatatct cttggaataa atgaaggaga
     9481 aaaaatagga cttattggtg taaatggtac tggtaaatct accttactca aaattattgc
     9541 aggagttgaa gaaagtgaaa ctggcaatat aacaaaagct aatggtattc ggatagaata
     9601 tctacctcaa aatccaactt acaatgagaa ttcaactgta cttgaacaag tatttaatgg
     9661 aacttctgaa gaattaaagc tacttggtga atatcaagaa attctagaag aacttaattc
     9721 aaactttaca gaggaattaa ataaaaaatt attatcggta cacgagaaaa tagatgcctt
     9781 aaatctttgg gatttagaaa gtgaagctaa atcagtactt acaaagcttg gtataaatga
     9841 ctttaatcaa aaaatagtag aactttctgg tggtcaaaga aagagagtct ctctggcatc
     9901 agcccttatt acaccttgcg agtttttgat actagatgag cctacaaacc acctagacaa
     9961 tgatactata gattggcttg aagaatatct taattcaaga aaaggttcat tgcttatgat
    10021 aactcatgat agatactttt tagatcgtgt tacaaataga attattgaac tagacaaggg
    10081 tagattattt agttatgatg ggaattattc aatatttttg gaaaagaaaa tggaaagact
    10141 tgcgttagaa gcaagtattg aagacaaaag acaaaattta ataagaacag aacttgcttg
    10201 ggtaagacga ggagctcagg ctcgtagcac taaacaaaaa gctcgtttac aaagatttga
    10261 cgaacttata aatagggact cttttaaacc tgatgaaaat ctcgatatat ctgttgcatc
    10321 aagtagactt ggaaataaaa taatagaaat acacaatata tctaaatcat ttgaaggaaa
    10381 tactgttata gataatttag aatatacttt aactcgtaca gatagaattg gcataatagg
    10441 aaaaaatggt atgggtaaat cgacccttat aaacatactt aatggagaaa tagaacctga
    10501 cagtggatat atttcaattg gagaaacagt taaaataggt tgtttttctc aagacgactc
    10561 tcatatgaat attgattaaa aaatagctac gcacactcgt gactttagtc atgaattagt
    10621 agctaaaata gtcagcatat agggaaactt atatgtagag ataggataac acctatccaa
    10681 tactacttga attgctggaa acccctaaag ctaaccaaac taaaacataa ggatgaaata
    10741 aacctaagtg tgaaagttgc gaaagtagaa aaaattggtt agatggtata aggttaaatc
    10801 ctaagtactt taaaatgggc aatcagcagg taa
//
LOCUS       DAMKOJ010000101        10752 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.110, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000101 DAMKOJ010000000
VERSION     DAMKOJ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.110"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            59..826
                     /locus_tag="PC592_003085"
     CDS             59..826
                     /locus_tag="PC592_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HDF4057024.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKLWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPIIADNYMFINCFWISGKFKGKGYSNLLLQECVDD
                     AKLKGKYGLVVLSSSKKMPFLSDAKYLKYKRFRLADTSVPNYELLYFPFTDNTPIPCF
                     KNCVKQRKLNENGIVLYYSNQCPHTEKYALILKKIANSRGIDANLIKFETANEAQNAP
                     APFTAYSLFFNGEFVTNEVLSEKKIEKFLENEVKKFN"
     misc_binding    1045..1258
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1504..2538
                     /locus_tag="PC592_003086"
     CDS             1504..2538
                     /locus_tag="PC592_003086"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDF4057025.1"
                     /translation="MSKIKVGIIGATGYVGAELIRLLINHDKAELTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDVCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKDDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKSNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCQEKVSVVFTPNLIPVNRGILSTIYCTKADNISINDIHRKLTDYYEFKEFIEVL
                     PLDKVASLKNVRFSNKCVISLHENVDTLIICSAIDNMIKGAAGQAIQNMNIMFGIEEN
                     TGLKNIVPSF"
     gene            2579..3796
                     /gene="argJ"
                     /locus_tag="PC592_003087"
     CDS             2579..3796
                     /gene="argJ"
                     /locus_tag="PC592_003087"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDF4057026.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     KIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3811..4671
                     /gene="argB"
                     /locus_tag="PC592_003088"
     CDS             3811..4671
                     /gene="argB"
                     /locus_tag="PC592_003088"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDF4057027.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFKEGIITGGMIPKIQGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            4701..5888
                     /locus_tag="PC592_003089"
     CDS             4701..5888
                     /locus_tag="PC592_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDF4057028.1"
                     /translation="MNNNSTISKWTEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYAGEKIINASGMDKIYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLELVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKIKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYEEIDEALEILKDILL
                     EIN"
     gene            5998..7020
                     /gene="argF"
                     /locus_tag="PC592_003090"
     CDS             5998..7020
                     /gene="argF"
                     /locus_tag="PC592_003090"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDF4057029.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVADTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGGIMLTE
                     NIADVKGADVIYTDVWVSMGEEEQYETRINQLKYYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTDEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7147..7764
                     /locus_tag="PC592_003091"
     CDS             7147..7764
                     /locus_tag="PC592_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF4057030.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTINSFFNSAKKFDFEGM
                     NKVMENNDEKYNDILKELDTKDPNEQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMLGMSFSGQDLTDEKTIEMLVSIMKEKQKSVKETYVTK
                     TVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSINALE"
     gene            complement(7958..8656)
                     /locus_tag="PC592_003092"
     CDS             complement(7958..8656)
                     /locus_tag="PC592_003092"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDF4057031.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSIPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKKSINI
                     PLLNIVEETVKKLPTLSQKVTLFSTSSTFESTIYQNGIIHNEHEFIFKDEWQIKLNNL
                     IQNIKIDKENPHNINIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(8818..10035)
                     /locus_tag="PC592_003093"
     CDS             complement(8818..10035)
                     /locus_tag="PC592_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HDF4057032.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWMK
                     DLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNKSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TNFGFNTKNLTNLHPRKDIDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPEKA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(10227..10640)
                     /locus_tag="PC592_003094"
     CDS             complement(10227..10640)
                     /locus_tag="PC592_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4057033.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
BASE COUNT         4192 a         1154 c         1819 g         3587 t
ORIGIN      
        1 aatgttaaaa taaagaatat atttaaaaat tatcatgtaa ttagaaaagg agataagtat
       61 gcagattatt gatataaata taaataatat tgacaatgaa catatatgtt gttcaatttc
      121 tgaaaaaaaa ggagaaaatt gtgttttttc taaaaaactt tggatgaaaa ataattttga
      181 taaaggtcta gtttttaaac gatttgatgt aagaggtaaa gcttttatag aatatattcc
      241 agcagaaaat gcatggtgtc ctattattgc agataattat atgtttatca actgtttttg
      301 gatatctggg aaatttaagg gaaaaggata ttctaatcta ttgctacaag agtgtgttga
      361 tgatgcaaaa ttaaaaggaa aatatggatt agttgtgctt tcgtctagta aaaaaatgcc
      421 ttttttatct gatgctaaat atctaaaata taagagattt cgtttagcag atacatcagt
      481 gccaaattat gagctattat attttccatt tactgataat actccaattc catgttttaa
      541 aaattgtgta aaacaaagaa aattaaatga gaatggtata gttttatatt atagtaatca
      601 atgtccacat acagaaaaat atgctcttat tttgaaaaaa attgcaaatt ctagaggtat
      661 tgatgcaaat cttataaaat ttgaaacagc aaacgaagca caaaatgctc ctgcaccatt
      721 tactgcatac agtctttttt ttaatggtga atttgtaact aatgaggtac tttctgagaa
      781 aaagattgag aaatttttag aaaatgaagt aaaaaaattt aactaaaagg agatataaat
      841 atactatttt gaaattatat tattttataa tttaatgtat tttgaaagtt tcttaagttg
      901 actaatgata atataaaact tatatcacaa tttgaatgca aaatggttaa agttaaccat
      961 atagaaaata tttccaaaaa tttataaatt atattgacaa acttaaaaat ataaactatt
     1021 atataaaaca ataagaaaat aaattgaaat cctgtgaaaa agagagtagc ataaaactaa
     1081 ttgatagaga gctgggaatg gtggaagcct agtaatgaat tttattgtga atagagcttt
     1141 ggaggagatt accagaagta atagtatggt aattggtggg tctcgcctta agagattaga
     1201 gtgggtaaga ttatcttatc aattagagtg gtaacgcggg tgtatattcg tctcttggtc
     1261 tttgaccaag aggctttttt aattttaagt atacatttgt agatactttt taatttgagt
     1321 tttaaagact attataattt tgccaataag agtggtaccg cggaaaatcg cctcttagta
     1381 tttataatac tgagaggttt tttgttttaa ttggaatatt ttaatctgtg tattatcaaa
     1441 tgattatcat ataataaaaa taaaattctg agactattta aatataaaaa tggaggtaat
     1501 caaatgagta aaataaaagt tggtattatt ggtgcaactg gatatgttgg ggcagaactg
     1561 attagattat taataaatca tgataaagcc gaattgacag caataggttc aaattcgtat
     1621 gttggaaaag atatagttga tatatatcca agtataggat ataaaaataa catgatatgt
     1681 atagaaaatg aaaaagttat agatgtgtgt gatgttgtgt ttacagctct tccacatgga
     1741 gttagtgaaa agtttgtaat aaaagcaatt aaatcgaaaa agaaggttat agatttaggt
     1801 gctgacttta gaataaaaga tgaagaagtg tatagtaaat ggtatggagt atcctttata
     1861 gataaaatct tacataaaaa agctgtatat ggattaagtg aaatatacaa agatgatata
     1921 aaagatgcag atataattgc aaatcctgga tgttatccaa ctagtatttc tttaccatta
     1981 atgccattgc taagttctaa attgataaaa agcaataata taataattga ttctaaatca
     2041 ggtcttacag gtgctggtag agaattatcg attagtagtc actttacgga ggttaatgaa
     2101 aatatcactg catataaaat agggaaacac agacatactc cagaaataga acaaaattta
     2161 agtgaatcct gccaagaaaa agtaagtgta gtttttacac caaatttaat accagtaaat
     2221 aggggaatat tatcaactat atattgcaca aaagcagata atatttctat aaatgatata
     2281 catagaaaat taactgacta ttatgaattt aaagaattta tagaagttct cccattagat
     2341 aaagtagctt ctttaaagaa tgttaggttc tcaaataaat gtgtaatatc attacatgaa
     2401 aatgtagata cattaataat ctgttcagcc atagataata tgattaaggg agcagcaggt
     2461 caagctatac aaaacatgaa tataatgttt ggtattgagg aaaatacagg tttaaaaaat
     2521 attgtaccat cattttagaa ataaaaagta ctaaactcat ataattagga ggataaatat
     2581 ggagattata aagggtggag ttacagtttc agaaggattt tttgcttcag ggattcactg
     2641 tggcttaaga aaaaataaag aaaaaagaga tttagctttg gtttattcag atgttttatg
     2701 tgatgcagca gcagtagtta ctcaaaataa agtaaaggga aatcctgttt atgttacaca
     2761 ggagcacatt aaaaatggaa aagcacaagc tatcatagta aatagtgcta atgctaatac
     2821 ctttaatgga aaagaaggac ttataaatgc ttataaaatg gccaaattta ccagtgataa
     2881 attaaagatt aaagaaagtg atgttttggt tgcatctaca ggtgttatag gaaagccatt
     2941 aaacatagat ttaatagaag aaaatatgga tgaattagtg aataatctaa gtaaacaagg
     3001 tcatattgga gcaagagaag ctattatgac aactgatatt ataaaaaaag aaatagcagt
     3061 agcaataatg tatggagata aaaaaataac tattggaggt atggcaaaag gttctggtat
     3121 gatacatcct aatatggcaa caacgttagg atttataact acagatgcaa atattgatgg
     3181 agttttacta aaagaagctt tgaaaattgc tgttgataaa agttttaata gagttagtgt
     3241 agatggagat acaagtacta atgatatggt aatgattcta gcaaatggaa aagcaaaaaa
     3301 tgatagaata aacaaaaaag atgaacatta tcaagtattt ttgagtgcac ttacatatgt
     3361 ttgtatagaa cttgctaaac ttgttgcaaa agatggagaa ggatgcacaa aactaattga
     3421 atgttatata aatggagcat taagtgaaga acatgcagta aaattagcaa aaacagttat
     3481 atcttcttca ttagtaaaga cagctgtatt tggagctgat gcaaattggg gtagaatatt
     3541 gtgtgcttta ggttatgcag gtgaagaaat agatatggaa aaagttgata ttatttttga
     3601 gagtatgaaa ggatatattg aagtatgtaa aaatggaaat ggactagatt ttaatgagga
     3661 aaaagcaaaa aaaattcttg aagatgacga aataagtata ttagtagatt taaatatggg
     3721 caatgccaga ggaaatgcat ggggatgtga tttaagctat gactatgtaa gaataaatgg
     3781 aagttataga aattaggagg gtatacttta atgattaata tagaaaaagc aaatacactt
     3841 atagaagctt taccatatat agaaaaacat cagggaaaga ctattgtagt taagtatggt
     3901 ggaagtgcaa tgaaaaaaga tggtctaaag gaatctgtta tggaagacct tgtgttaatg
     3961 agttatgttg gaatcaatat agttttagta catggtggag gggcagaaat caataagatg
     4021 ttagcaaaag tggatataga aagtaaattt gtaaatggtc ttagatatac agatgaagag
     4081 acaatggaaa ttgtaaaaat ggtacttgct ggaaaggtta ataaagatct agtaaataaa
     4141 atacatacaa aaggtggaaa agcagtaggg ctttgtggaa tagataataa tatgatttta
     4201 tgtgacccat ataaaaacta tgaacttgga tttgtaggag aaatcaaaaa agtaaatgtt
     4261 gagcttatag aatcttgtct aaagtcaggt tatatttcag taattgcaac tataggtgtt
     4321 ggagatgatg gagaaactta taatataaat ggtgacacag cagcttctgc tatagctaaa
     4381 gagttaaatg cagataaatt gatacttctt acagatgtac ctggcttgtt aagagagcca
     4441 gatgaagaaa aatcattaat aacagaagtt atattagagg atgtcgataa attatttaaa
     4501 gaaggtataa ttactggagg tatgatacct aaaatacagg gatgtgtaga tgccttaaat
     4561 aacggagtaa atagggtaca tattttggat ggaagagttc cccattctat aataacagag
     4621 ctatttactg atagtggaat aggtacatta ataagaaaag aaaatgaata aaattataag
     4681 tttaagaagg gagaataaga atgaataata acagtacaat ttcaaaatgg actgaatatt
     4741 ttatagatac atataaccaa cctaattttg ttatagatta tggggaagga agttgttttt
     4801 ttgatactaa tggcaataaa tatatagatt ttacaagtgg atatggagta tcttctcttg
     4861 ggtatagtaa cagtaattta aagaatgctc taaaagagca agtagataaa ttattacata
     4921 cttcaaattt atattttaat gagccagtgc tgtatgcagg ggagaaaata attaatgcaa
     4981 gtggaatgga taaaatatat ttttgtaatt ctggaacaga agcaaatgaa acagcattca
     5041 aaatagcaag aaagtatagt agtgataaat atggtaatgg tagaggaact attataagtt
     5101 taaaagactc ttttcatggt agaacgatga tgtctttaat ggcaactggt atggataaat
     5161 accataagta cttttatcca cttcccgaag gttttaaata tatagaaaga aataatattg
     5221 aagatttaaa aaataatctt gattcgacag tttgtgcaat aattcttgaa gcgattcaag
     5281 gtgaaggagg agttaatgtt cttgaaaaag attatgtttt ggaactagta aaaatatgtc
     5341 aagaaaagga tattgtagtg atttttgatg aagtacaatg tggtatagga agaactggca
     5401 aactttttgg atatgaatat tttgatgtaa aaccagatat agttactgta gctaaagggc
     5461 tgggagcagg gataccagta ggaggagtat tggtaaataa aaaactttca aaagtactag
     5521 gaaaaggaga ccaaggtaca acttttggag gtaatctatt agctatggtg gcagcttcag
     5581 ttgtattaga tgagatatct aaggatggtt tttataatga agtattagaa aaaggaaatt
     5641 atataagaaa atctattgaa agttttaata ataaagttgt attaaagata aaaggtattg
     5701 gtctaatgat aggaattgaa actaatattg aatctagtat tatagaagag aaagctagaa
     5761 aaaaaggatt gcttattttg actgctggaa aaaatgtatt gagattttta ccaccattaa
     5821 caatcagtta tgaagaaata gatgaggctc ttgaaatcct aaaagatata ttactagaaa
     5881 ttaactaaat attcaaaaaa tagtttgatt aaagataaaa attagaagta aataaaaaag
     5941 taaagtgcta acaagtttaa ttgaatttaa aaagtttata aaaaggggcg aattaatatg
     6001 aataatataa gtttaaaagg gaagagtttt ttgacattaa aggattttac aaaagaagag
     6061 attagatatt tattaacttt atcaagttat ttaaaaacta agaaaaaagt tggtataaaa
     6121 ggcgatttgc tacaaggaaa aaatatagct ttattatttg agaaaacatc aacaagaact
     6181 agatgttcat ttgaagtagc agctcatgat gaaggagcac atgtaactta tctaggtcca
     6241 aatgattgtc atatgggtaa aaaagagtct gtagcagata cagcaaaagt tctaggaaga
     6301 ttctatgatg ggatagaatt tagaggcttt aaacaagaaa cagttgaaag cctagcaaaa
     6361 tattctggtg tacctgtttg gaatggactt acggatgaat atcatccaac acaaatactt
     6421 gcagactttt taacagtaat tgaaaatgta gataaagatt tgaataaagt taaatttgta
     6481 tatgttggtg atgctagaaa taatatggga aactcactga tgataggatg tgctaaaatg
     6541 ggaatccatt tcgtagcact agcacctaag gagctttggc caaatgaaga gttggttaag
     6601 gaaatgaagg aaatagccaa gaaatctaag ggaggcataa tgttgactga aaatattgct
     6661 gatgttaaag gtgcagatgt tatatataca gatgtatggg tttctatggg agaagaggag
     6721 caatatgaaa caagaataaa tcaacttaag tattatcaag taaatatgga tatgataaag
     6781 aaaactgaaa atgaaaatgt tatattttta cactgtcttc cagcatttca tgatttagaa
     6841 actaaggttg ctcaggagat ttatgaaaag tttggattat cagaattaga ggttacagac
     6901 gaggtattta attcgaaata ttcaaaggta tttgaagaag ctgaaaatag aatgcataca
     6961 ataaaagctg ttatggtttc tactatgact gatgtaaata tgaacaataa tttaatatag
     7021 atattcctta atttagattt tgttttaata aaaatttata aaatatttta aatatattat
     7081 tcaaaaacta tcattatatg ttaaaatagc ttatgtatca acaaattaag agggaggatt
     7141 tgagatatga aaaaaatcat attagcttta acaacttttt tattagcaat atctttaaca
     7201 gcatgttcaa gtgcaaaacc agaagataca atcaatagtt tttttaacag tgcaaagaag
     7261 tttgactttg aaggcatgaa taaggtaatg gaaaataatg atgaaaaata taatgatata
     7321 ttaaaggaat tagatacgaa agacccaaat gaacaatatg ttttagatta tctaaaacag
     7381 aatgcgtcta aaatcacata tacaataaaa gacagtgaag ttaaaggtga taaggctaca
     7441 atcaaagtag aatgtaaatt tatagattca acaccgttgc ttcaagaaat agtagctgag
     7501 gcatttacaa agatgcttgg tatgagtttt tcaggacaag acttaactga tgagaaaaca
     7561 attgaaatgt tagtatcaat tatgaaagaa aaacaaaaaa gtgttaaaga aacttatgtg
     7621 acaaaaactg tagagtttga atgttctaaa aaggataata aatggataat aagttcagta
     7681 aatgatgcag tagctgatgt attgttatct aatcttgtta cagcaggaca agaattttct
     7741 aactctataa atgcacttga ataatattgt ttaggtgtag taaagtaata aacatatatt
     7801 tatttatgaa ggataccatt tttggtatcc tttttattaa tataatgaaa tacatggtta
     7861 atttctatat tgtcaagaaa ctatgatata tgttataagt ctatactatt taagataaac
     7921 ttataacata tattttttat aatatagtgc atgaaattta tttaactaat tttagatatt
     7981 tattgacaac tgattcagcc aagcattttg atgaatcaac aatatttatt gaaggatatg
     8041 atttttctaa aactacattt aaatcagtac aagcaattac tatattttct atagattcat
     8101 ttttaacatc ttcgataagt ttattccaaa tattaatatt gtgtggattt tctttatcta
     8161 tttttatatt ttgaataaga ttgtttaatt ttatttgcca ttcatcttta aatataaatt
     8221 catgttcatt atgtattata ccattctggt aaattgtaga ctcaaaagtt gaactagtcg
     8281 aaaaaagagt tactttttgt gagagagtag gtaatttttt aactgtttct tctacaatat
     8341 ttaatagtgg tatattaata gactttttta attctttaaa gtatatatgt gctgaattgc
     8401 atggcattgc aataaaattt acaccagttg actcaagttt ttgtaatcca tcaattatag
     8461 tttctttcat aagttcatga tttattggac ggtcaatata aaatggggta ggtattgaat
     8521 atatcatcat ctttggaaat tcatcatcat attttgctcc atattgagat tgacactcat
     8581 caataattaa atcaacaaaa ggggctgttg accttggacc cattccagcc aaaataccaa
     8641 ttaatttttc attcataaaa agtatctcct ttatacataa atatatttat gtataaaata
     8701 aaaatttata aaaacataaa attatatttt ataatagatt atattataca cttgtataat
     8761 ataagtataa agtgagtttt tagattatat attttaatat actttcttat ataaaaatta
     8821 ttttaaatca agattatcta gtatttttaa aaaaattttt acagcggtat ccaaatcatc
     8881 tacagaaaca ctttcattag gattatgact tacgccccca gcgcatctta taaataccat
     8941 accaatatca gttatattat ccatttcctg agcatcatga ccagcaccac tataaatata
     9001 aaaaggatta agatttaaat ctataaaact tttttctatg atttttgtta ttttattaga
     9061 acatggtaca ggaacatttt caaaagcaag ttcacttgta tagttaagtt ttctattttc
     9121 acatatatgt gatatttcat taaatatctt ttctacagaa ttatcaagaa tttcttgaga
     9181 acaagagcgt acatcaagag taaattcagc tttttcaggt accacatttg atgaagatgg
     9241 ataaaaattc atctttccta cagtagcaac caaatcagca gttgtcttag ctactttttc
     9301 gatagctaag acacattcac aggcacaaca tccagcatca agtctcatgt tcattgggag
     9361 tgtaccagca tgtccagatt taccatttac tgatatctta aaacttttga atcctgtaat
     9421 acttgataca attccagcag gaagagattc attttctaag acaggtcctt gctcgatatg
     9481 aaattctaaa tatgcatcta tatcttttct aggatgcaaa tttgttaagt tttttgtatt
     9541 aaatccaaaa tttgttacag cttcttcaag tgtaattcca ttttcatcaa cagatttaag
     9601 aagttcctct ttaaaagtac cagcaaaaac tttacttccc attaaagaag tttcaaatct
     9661 agttccttct tcttcagcga aagcaattag tttaatattg aaaggataag acttattatt
     9721 gtgttttgct tcttcaagac caactagagg cactattatg cctaacatac catcaaatat
     9781 acctccacac tttacactat cttgatgaga tgcaactact aatgtgggag catttggaaa
     9841 gcttgattta tatgtaccta taacatttcc aatgtcatca atttcaatat caagatttaa
     9901 atctttcatc catgaactga ttaaatcaat agatttttta tgttcttgag tcaagataag
     9961 tcttgtaaga ccatttgttg ttgaacttat ttttcctaat gtttgtagat aatccataca
    10021 tttttttcct aacatattta cctcctaaaa atataatttt tatttaagct aagattagct
    10081 tttatactta taatttttga actttcaaat aattttgtat gtatagtaaa atactatttt
    10141 agtattaata atgatataag aacataaagt ctgtagacga agagcagaag ttttaagtta
    10201 aaaaatatta aatgtgattt ttattattat agtatttttc taaaataata tctctttcca
    10261 gttagaggat aattttcaag tgaaaatact ttatggtatc caaatttctc ataaaattta
    10321 ggtgcttgaa aactgaatgt atctaaaaaa acatatttac aacctcgttc tttagcaatt
    10381 ttttcagcct tatataaaag ttgacttcca gtacctttat atctaagctt ctcactaacc
    10441 cataagtatt ttatagaaag ccaattacca tgagtaacac ctataaaacc tgcaacaatt
    10501 ttacctgctt tatctcgaat atatattcct aaatccactg gatttttatc ttcaagtcta
    10561 gcaagattat attttaataa tccttgaaaa atagtatctt catcttgttt ttctattttt
    10621 tctgtaattt ctaattccat atttgaactt tctccttgta taatcttttg catattggta
    10681 ttttttaata aaatcagtag aaagaaaata gtttaacatt attctaatag tcatttatgc
    10741 taatgtcaaa ct
//
LOCUS       DAMKOJ010000102        10737 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000102 DAMKOJ010000000
VERSION     DAMKOJ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.111"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            249..1409
                     /locus_tag="PC592_003095"
     CDS             249..1409
                     /locus_tag="PC592_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF4057034.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGIYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGTGSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPRFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISRLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLS"
     gene            1749..1910
                     /locus_tag="PC592_003096"
     CDS             1749..1910
                     /locus_tag="PC592_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057035.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2103..2732
                     /locus_tag="PC592_003097"
     CDS             2103..2732
                     /locus_tag="PC592_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDF4057036.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLNCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTFKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVVLCGDFNEKNVFLSMFNDMA
                     ISLNKSYLSTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2972..4231
                     /locus_tag="PC592_003098"
     CDS             2972..4231
                     /locus_tag="PC592_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF4057037.1"
                     /translation="MGRRATRVSRLGKEKKRNIVIVLVVLIIAMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKSEALRAITDKYTPEDLNLTYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLNYTDSVIGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLAGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4400..5395
                     /locus_tag="PC592_003099"
     CDS             4400..5395
                     /locus_tag="PC592_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HDF4057038.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNL
                     EEKMLQSIDRGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVVQVKKDYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5641..6708
                     /locus_tag="PC592_003100"
     CDS             5641..6708
                     /locus_tag="PC592_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDF4057039.1"
                     /translation="MSNIKIIASNKCWIEDIAKKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGILKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYAKDGLEVESEKAIDYIKNHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTKISLYSLSH
                     GAGRKWSRSVCKSRLKSKYNKDTIKQTKFKSQIICSDLNLLFQEAPEAYKNIEQIIES
                     LMEHKLIQVVATMKPLITYKG"
     gene            7222..9132
                     /locus_tag="PC592_003101"
     CDS             7222..9132
                     /locus_tag="PC592_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF4057040.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLNPSGNIGVVR
                     RKLAENKEARKIIENSNHVPLEGLFNAGSTIDKIEKGMVIEPIELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKNIEDEINYCIKSNKVDSNASKELKKVRRNIEIT
                     EAKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVDGTILDTSSKGNT
                     VFIEPISVSNLSTELIMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMNLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTTGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNVEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPIDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDTLFTNFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9195..9818)
                     /gene="ytaF"
                     /locus_tag="PC592_003102"
     CDS             complement(9195..9818)
                     /gene="ytaF"
                     /locus_tag="PC592_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HDF4057041.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFFLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLFGCLLGNMFVKNINLNLSWLSGLILLVIGFIKIC"
     gene            10006..10650
                     /locus_tag="PC592_003103"
     CDS             10006..10650
                     /locus_tag="PC592_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4057042.1"
                     /translation="MEQHSKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFKNNNNQIFNTDSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4417 a         1064 c         1737 g         3519 t
ORIGIN      
        1 ttatctttac aaataaaaat tttagtaata aaataattgt tgaaaaagat tttaaattca
       61 gattattcat ttctaaagta attaatatgc aaatctttat taatatgtgt caatagttag
      121 gtatatatgt atttaattag catgatatag ataagagtat ttattttaat tgtctattat
      181 ctgaaaaagt ctttacttaa aaatcataaa aaatcaaatt aattaggaaa agaaagggtg
      241 tgtataatgt gattgagact ggatttgtat attgtagttt cttggttgta ttcgtaggtg
      301 taattttctt tatggttgat aaattgaagt ggaaggtatt tgatgttatt aatccaatgc
      361 ttttaatata tttaggttca gctatacttg gatcatttgg tttatttgca cagaatgaag
      421 atgttggaat atatcaaaat ataataacag tgaacttcct tccattaatg ttagtgttct
      481 tgttaattca atgtgattta agaaaaatac taaagatggg acctaaaatg ttattatcat
      541 ttttctgtgc tacatttaca tttatgcttg ggtttgttat agcattcata atttttaaaa
      601 attcaatggg tacaggttca tggaaaattc ttggggcagc atctggttca tggataggtg
      661 gctcatcaaa tatgattgcc gcagctaatg ctctaggagt tgcagaagaa ggtcttagtt
      721 atgcaatact tatgggttct ataggctata cagtatggat gtctgtttgt ctaatgtctg
      781 tgaaatttgg acctagattt aacaaatgga caaagtgcga tacaagtttt atagatgagg
      841 ttacatcaaa acttgaaaaa gaaaataaag ataatacagc acctacgttt gtagaactta
      901 tgattttact ttctgttggg tttggtgttg cttcttttgc acaaattgta tctaagatac
      961 ttccaacttc agggatactt aatgaaacta tgtgggtagt acttgttgca tctacagtgt
     1021 caatattatt gggtatgaca aaaatatcaa ggcttaaggg gagcacattg gtaggaaatg
     1081 tgtttatgta tttactcctt gcagccacag gtagtaaggc aaatttcttt ggattgtcag
     1141 aagcacctgt ttacataatg tttggattgg tagtagtcct tgtacatgct atttcattta
     1201 tagggcttgc taaactattt aaacttgatt tatttacttg tgaggtagga agtatagcta
     1261 atatcggagg agtaactaca gctcctatga ttgctggggt tcacaatcct gtattaatac
     1321 cagtaggtgt acttatgggg cttctaggaa atattatagg tacttattgt gctcttatgg
     1381 taactcaaat actacatatg ttatcttaat aaaaatataa tataaaatta atcatttaaa
     1441 taagaaaaaa catttcaatt taagcataag cttttattga aatgtttttt atttgacaag
     1501 ataatttatt tcaagaagat attttgacat atttagcgta taatattgta aaatttacta
     1561 aaaatgagat atatttaatt tttatattga atcgaacgtc tgtatgatgt ataataaata
     1621 tatagaacga atgtttgcag aacggatgtt ttttgaattt attttaataa tttatgaata
     1681 tatatcagaa tgcataaata tatttaaata taaagattaa aaagaattta aaggagtgtt
     1741 gataacttat gataattcca tcaagaagaa tacaagatat aacattaaca aatttaaaaa
     1801 atggtgaagt aactttaatt gaattggatg aaatatacaa gaagatggga tttttatttg
     1861 ttgttagtga aggcaaatta aaaaagataa aaaaggagaa tcatcattag aaatgaatga
     1921 aataataaat attataatag tttataaaac ctaacttatg tagaatataa atacttaagt
     1981 taggtttttt tgtgataaag tttataagta ctcaatttta taagataggt aatagtctta
     2041 agtgaaaagt aaataagttt aaattttaat aagtattata ttacataaga ggtgatatta
     2101 ttatgaaaat agtaacctac aatattcata aagggatgga ttcaaataat agattaactc
     2161 taactaaaat ggggttatat ttaaaacaat tgaattgtga tgtaatttgt ttacaagaag
     2221 tattgtatcc tcagttttta gctttaaaag ctgttttaaa tatggatggt gtctttgcca
     2281 caaatgtaaa aaaagtaaat atgatatatg gtatttgtac atttacaaca tttaaaatgt
     2341 taaacagtaa tcattttttc ttaactagca aaaaagaaca acgaggagct ctttgtataa
     2401 ctatagatgc atatggaaga attataaatg taataaatac tcacttggga cttgatagac
     2461 aggagagagc aaaacaatta gacgaaataa tagactatag gaatagatta gtggggatag
     2521 ttgtcttatg tggtgatttt aatgagaaaa atgtcttttt aagtatgttc aatgatatgg
     2581 ctatttcact aaacaagtct tacttgtcaa cctttgaaaa atcaaactct agaatagatt
     2641 acatttttgt taataaaaat actgaactaa aaggatatac agtagaaaaa atttacctgt
     2701 cagaccatta tcctgtaata ggttatattt gaatttcaat ataaaaaaat taattattat
     2761 aagataaaca atttttttgt taagaaataa taaaaaaaat ataataaaaa aatatcaaaa
     2821 ataaaactaa ttataagaca taaatttaca ataaagttac atttgattaa attccttgtt
     2881 taacaaaagc tattcaaata taatctaagg tagttttgaa atgggaactc tattatgtaa
     2941 aattaagtta gtgttaaaat gaggtgaatt tatgggcaga agagctacaa gagtttcaag
     3001 attaggtaaa gaaaaaaaac gaaatattgt aattgtattg gtagttttaa tcatagcaat
     3061 gggtggattt acttattttt ttaacagtaa atttctgtac aatgggaaaa tcgctaaaaa
     3121 tgtatatata gaaggagtaa atgtatctga tatgactaaa tcagaagcat taagagctat
     3181 aacagataag tatactccag aagatttaaa tcttacttat gatgggaaaa aatatacaat
     3241 atcaccaaaa gatattgatt taaaatatga tacagaagat gttgtaaaag atgcttatga
     3301 aagtacaaaa aaagggtcct attttcaaaa cttaaaaaaa tatattgata taagagtgaa
     3361 taaggcaaat atgaagataa aagctgaata tgatgaggca aagcttagtt cgaaggtgtc
     3421 ttctatagca gatagtataa atgttaagat gaaaaatgct tctattagcg ttggaagtgg
     3481 tggactaaat tatacagact ctgttatagg tagagaattt gatttggcag caaataaaga
     3541 gtctatatat aatatgataa aaaataaaga gcataaaact ttagaactta aagtaaatct
     3601 tcaaaaacca gatataacaa ctgagcaagt aaaaactgta aattctgtta taggtcaata
     3661 ttcaaccact tattcacaag ctgtagaggg taggtcatat aatgtaggat tatcagcaag
     3721 aaaaactagt gatgtattac taatgccagg tgaagaattt tcatacaata aacttacagg
     3781 acctagtaat aaagcaaatg gttacaaaga tgcacctgtt atagtttatg gtaagctaga
     3841 acaatcagca ggaggaggtg tttgtcaaac atcttcaaca gtttataatg ctgctcttct
     3901 cgcaggtatg gagataactc aagttacaaa tcattcatct gcatccactt atgtacctaa
     3961 aggtagagat gctactgtta gtgatggggg attaaactta aagtttaaaa atccatataa
     4021 gcatcctgta tatattaaaa attatgcagg tggaggaagt gtatcatcag taatctatgg
     4081 taattctggt gacaaaccga atatatctat agaggtaaaa caaactggtc agaataaata
     4141 ttctacatat cgaatattta aagattcaag tggaaaggtc ataaaaaaag aacatatatc
     4201 aaatagttct tataaagaat taaaaaaata aataattttt tagaaaaata tttgtaatat
     4261 aaaaacaagg aagtttataa cttccttgtt tttttgtaaa aatcaacact attagttctt
     4321 gttttaatat tacaatcatt aatatataga aaatattcct atatattggt ataattgtaa
     4381 atagatttag ttatataaaa tgtatgagga ggtgacatgg ttgaatttta taggcaatag
     4441 atatgaggta gtaaattctg atgacgtttt agaaattaac aaaatctata aagctagaga
     4501 tgttttttac agaaaaaatg ttctaataaa agttataaag cacaataatt atatctgtga
     4561 agattttgtt tcaaatttaa ttgatgaaag tactgcttta gatgagataa actctcctta
     4621 tatactaaaa ataatagatg ttgggattca ttgtacagaa gaaacaacat tgtattatgt
     4681 tgtaagtgaa gactttaatg gtatcggact agatgaatta attctaggta attatcttca
     4741 tttagaagca attgtaaaca taatgataca agttttaaaa gctttagaaa tgatacatag
     4801 gaatcattca tatcatggta gtttaaaatc aagtagtata atagtagata cagaatacaa
     4861 tataaaaatt tgtgattttg gaattacaaa agcaaataat ggggttaata caagaagcta
     4921 tggaaacagg agatatttat gcccgcatca actatgtata aattataccg ataaagaaag
     4981 tgattttttt gcaacaggtc ttattctatt tgaatctata tttaaaaaat tgccatttgg
     5041 agaatcaaat ttagaagaaa aaatgttaca atctattgat aggggattag actggaatag
     5101 tataaaagca attaatggaa atacagaact tataaatgtt ataaaaaggc ttcttggaag
     5161 aaataacaag tatactagag ccaatgatat tattattgat ttaagtaaag taatgtatga
     5221 aaaagcatat atagaagttg aagatgagaa agaagaagaa cagaaacaag ataaagttgt
     5281 acaggttaaa aaagactata aaagtaaaat gagaaaaaaa ttacataaaa aacttgttgt
     5341 tgctggtcta gctatagtca tgatttcaat gattattatc agttccataa tataaaaatt
     5401 gtatattaag cattttaaaa tcaatatcta taaatgatat acatagaaat tttagtgtag
     5461 tcttaaatta tgaaaggaag tggttattat gttaacaaaa aataatgagg tattaaatgt
     5521 ttaggagtat tttaacaaat agccacctgc ttttacagtt tagaataaaa aagctgtggc
     5581 taaaggtcac agctttttgc tactttttaa aggcaggagc atattaaaaa ggagcaaatt
     5641 atgagtaata taaaaataat agcaagcaat aaatgttgga ttgaagatat agcaaagaaa
     5701 caacttgaag atatttcaaa gttaaatgga attttaagag tagtaggatt acctgactta
     5761 catgcaggta aaatacctgt aggtttagca gttgagacta aaaatattat ttatccacat
     5821 ataattggaa atgatatagg atgtggaatg actttattta aaactgggat tctaaaaaag
     5881 aaatttaaaa aagataaatg gattaagtca cttagcaaga ttaaagattt gtctgatata
     5941 gaaataaaaa acacatataa agaagaatgc ccaattttaa atttaggaac tatagggagt
     6001 ggaaatcatt ttgtagaaat tcaatgtata agtgaaattt ataataaaga acaatttgaa
     6061 caattaaaat tttcatctga tgatattatg atgttagttc actgtgggtc aagaaattat
     6121 ggagaagata ttttaaaaaa attttatgct aaagacggac ttgaagttga gagtgagaaa
     6181 gcgatagatt atattaaaaa ccatgataat gctttaatgt gggcagagcg taatcgtgaa
     6241 gctatcagta aaaaaattat gcagtcaata ggtacgtctg gagatgttga aacaatattc
     6301 tctataaatc ataactttat agagaaaagg gaagataaat ttatacatag aaaaggtgct
     6361 gtttcaagtg aaagaggagc tgtgattata ccaggctcaa gaggtagtct atcatatata
     6421 gttatgccta ctgaaaatac aaagatatct ttatattctc tatcacatgg agcaggtaga
     6481 aaatggtctc gctcagtttg taaatctcgc cttaaaagta agtataataa agatactata
     6541 aaacaaacta aatttaaaag tcagattata tgtagtgatt taaatttatt atttcaagaa
     6601 gctccagagg catataagaa tatagaacaa attattgaaa gcttgatgga gcacaaactt
     6661 attcaagtgg tggcaactat gaagccattg attacttata aaggataatt ttgaaagcaa
     6721 aaaaattaaa ataatattat agctagtcaa taataaaacc tataaaaatg ttttattatt
     6781 ggctattttt tctttgtaga aatgataatt ttgagagtta aattctctaa catatatatg
     6841 gttacaaagt aaggctatat taaaaattga atatacatga attgatgcca gcataaatga
     6901 tttcaaaata taaattaaat aataaatcta tttttaatat gtaaaaatgt caaataaatt
     6961 atttttattg acatgaatat ctagtttatg aaataatatt aggagcactt atataagtgt
     7021 ttaaataaga gtagaaaagg agcagtgttt tatgaaaaaa aatactaaca ttaatgagtc
     7081 cggagttaaa cttcttaata aataaggagt ttgatgtata gtaactcctt atttattaag
     7141 tcgtttacaa aataatcatt atcaaaataa atggtatggt gatttaaaaa ccaatgactt
     7201 ataaataaag gagaaaaaat aatgaatagt aatacatttg aaagattaca actaaatgaa
     7261 gttaaggaat taataaaaat acattgtgta agttcgcttg ggaaaaattt aatagataaa
     7321 ttaaatccta gtggcaatat tggagtagta agaagaaagt tagcagaaaa taaagaggct
     7381 agaaagataa ttgaaaatag caatcatgta ccacttgaag gattgtttaa tgcaggttct
     7441 actatagata aaattgaaaa aggaatggta atagaaccta ttgaacttgt aaacattgaa
     7501 gattttttaa gaggttgtag gaagatgaaa gcttttatgt tagaaaaaga attttattca
     7561 cctacattaa gttcttatgc tttaaatata acagaatgta aaaatataga agatgagata
     7621 aattactgta taaagtctaa taaagttgat tctaatgcaa gtaaagaatt aaaaaaagta
     7681 agacgaaata tagaaattac agaagcaaag ataaaagata gattaaataa atttataaca
     7741 tcaactgtaa ataaaaagta tatacaagag tttataataa gtaaaagaaa tgataggtat
     7801 gtaataccaa ttaaatcttc ttataaaaat gaagttgatg gtactatatt agatacatca
     7861 tcaaaaggaa atactgtatt tattgaacct attagtgttt caaatttaag tacagagtta
     7921 attatgctaa aagctgatga aactattgaa gaatacaaaa tattatctta tttaacagaa
     7981 cttatatttg agaagataag tcagataaaa ttaaatatag agatactttc agaatacgat
     8041 atggtatttg caaaagctaa atatagtcaa aaaataaaag gaattactcc aaaaataaat
     8101 aataatggct atataaaaat aattaaaggt aaacatccac ttctaacagg agatgcagta
     8161 cctttagatt ttgaaatagg caaaaattat agaagtctta taataacagg tcctaatgca
     8221 ggaggaaaaa ctgtaaccct taagactgtt ggtctgctaa ctttaatggt tcaatgtgga
     8281 tttgatattt ctgcaaaaga aggtagtgaa tttagtgtat ttgaaaaagt ttttgtagat
     8341 ataggggata atcaaagtat tgaaaatgcc ttaagtactt tttcatcaca tataaaaaac
     8401 attgcagaga ttatgaactt atcaaataat tctacccttg ttctgtttga tgaaatagga
     8461 agtggaactg aacctaatga aggagctgga ttagcaatat cattattaga agagttttac
     8521 aaaatgggat gtataactat agcatcaact cattatggag agataaaaaa gtttgctaca
     8581 ttgcatccag agtttgaaaa tgctggtatg atgtttgata aagaaacgtt agaaccatta
     8641 tataagttaa ctactggaaa atctgaagat agtaatgccc tttttatttc taaaaaaatg
     8701 ggaataaaaa atagagtttt agatagggct aaagaatatg taattgatag aaactacaat
     8761 ttagatttag ttaaaagaag taagctacaa tctaatgttg aagacaaaaa tagttctgaa
     8821 gtcattttaa actatacaga ttataatgta ggggataagg taaaattact agatgaagat
     8881 gattttggaa ttgtatataa gcctatagac aagtttaata atgtagaagt attgtttaat
     8941 gataatttta tttcagtaaa tataaaaaga ttacaactta gcataaaagc atcagaattg
     9001 tatccagaag ggtatgattt agatacatta tttactaatt ttaaagaaag aaaattggaa
     9061 aaagatattc aaagaggttc aaaaaaagct cttaaaaaga ttcagaaaga aattagagag
     9121 aatagaaaat aaatataaaa aacataaaag aaagcaatct aaagagcaaa ttttatcttt
     9181 agattgcttt cttattaaca tatcttaata aacccaatga ctaacaagat taagccactt
     9241 agccaagata agtttaaatt tatgttttta acaaacatat ttcctagtaa acaaccaaat
     9301 aatactgcaa ttatatttga tattaaagaa aatagaataa cctgtatata attcacacct
     9361 acaagaccac taccaaaacc aatagctaat ccatctaaac ttaaagcaag tgcaagtgta
     9421 aatgcttcag cagatttaag cactttagat ttgcttgtat ctaagacgtc aggttcaata
     9481 cttacattaa aatttaattt aaggtctaac atattaaaat tataattctt tgagtgtata
     9541 gattttttct taaaataaga tttaaaaaag ctttcaatta gtctagcgct tcctaaaaaa
     9601 aataagataa agaaacatat tagcattgtt atattttgag gtaaaaagtc tctaactatt
     9661 gtacctgcaa aaagcgatat tgccaaaata gctgaacaaa ctacgctgat aattatattt
     9721 gaatataagg gaactttaac tttatttacg ccatatccaa agcttgtcac aaaggcatct
     9781 atacaaagag aagtaactaa taaaattgat tcaatcacag tagattaaca tcctttctct
     9841 taaattttat acttatatta gttatagtat tgtaaaaatg gataaattgt tacagataat
     9901 ccaataaatt gttgataaaa tttcaacatc atacaacacc taaataaaaa aagaatcata
     9961 tcatataata atataaaacc aatcataata aagcaggtga aaataatgga acaacatagc
    10021 aaggttggga atttcggtga tttgttgaag attttattag atgaaaaaga attatcaatg
    10081 ggagaattaa gtaaaaaaag tggaattgat aaatctacta tatctcgtat agctaataat
    10141 aaacaaaagc caaatataaa tcatttagaa aagatggcaa tacatttaaa tattaaccta
    10201 gaagaactgt tgaaagcttc aggatatgaa tttaaaaaca ataataatca aatatttaat
    10261 acagatagtg attttagtaa ttttgatgat attcttggat ttgcaaattt aatcaatgat
    10321 aagaacttta atggaaatat tgaaaaagag ttaagtaagt gtaagttgta tgtccaaaca
    10381 gatgaaggta aaaaattact ttttgataat tttaataaaa aaatagattc tattgaaaaa
    10441 caagggcaat tcacagatag attaagacaa atgtatgctg atttttgtac agacggactt
    10501 acaataaaga aatatttatt gattggaagt atgctacttt actttgttat atcaacagat
    10561 gtaattccag atttcgtgtt cccaatagga tttatggatg atttagtggc attaaatata
    10621 gttacaaaat tacttaaaaa tgataagtaa gttttagaat catattaaat atataaataa
    10681 aaatatataa aagttattat tttttataag aaacaaatta aaagtacaag aaacaga
//
LOCUS       DAMKOJ010000103        10326 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000103 DAMKOJ010000000
VERSION     DAMKOJ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10326
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.112"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            141..395
                     /locus_tag="PC592_003104"
     CDS             141..395
                     /locus_tag="PC592_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057043.1"
                     /translation="MENNDFKLTICIFAFVTGVVVLFCCIGLGEFSVEHIIQQNGGTM
                     DTDQYNIYLDQSISQYRNFGSILALLGGLGILFDKYIRKY"
     gene            440..763
                     /locus_tag="PC592_003105"
     CDS             440..763
                     /locus_tag="PC592_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057044.1"
                     /translation="MATEIFTVKITPIEAQKIIKENLNADLVFSDSYNLGNDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKAISTGSAIGVLKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(1033..1227)
                     /locus_tag="PC592_003106"
     CDS             complement(1033..1227)
                     /locus_tag="PC592_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4057045.1"
                     /translation="MINYMIEIIYSEKISEVENILKIENIQYEFTSRDGFIFFGFYDM
                     TDAYKFETLCSDEKIQFKRI"
     gene            complement(1599..3218)
                     /locus_tag="PC592_003107"
     CDS             complement(1599..3218)
                     /locus_tag="PC592_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF4057046.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPILGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLILNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFKNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            complement(3527..4267)
                     /locus_tag="PC592_003108"
     CDS             complement(3527..4267)
                     /locus_tag="PC592_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057047.1"
                     /translation="MKDFKDDIELIINDFFDCCNIPTKVFSKDLKEICSIGYDPTLET
                     YFSSLNIFSNINSTDFISNKNLFYIMLSFCDDLHFLVMPIHKFDVSSGYFIVGPFKSC
                     INNDIEFSNIPFKPLSCLDYISNLLSEICLDKMKHRPALSFYVKKTIDYIHKNYSEDI
                     TVSDICNDLQLNKSYFCSLFKKESGYTFTNFLNKVRVEKSKKYLLEKDLSILDVAVLV
                     GFNSQNYYSMVFKKFNNLTPIEYKNIYN"
     gene            4416..5165
                     /locus_tag="PC592_003109"
     CDS             4416..5165
                     /locus_tag="PC592_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4057048.1"
                     /translation="MKKIAIYGKGGIGKSTTTSNLSASLSHLGYKVMQIGCDPKSDST
                     KNLMKGKFIPTVLDVLKEKKEELKLEDIVFEGYGGVLCIEAGGPTPGVGCAGRGIIAA
                     FEKLEELKAFEIYNPDVVIYDVLGDVVCGGFSMPIRNGFANEVYIVTSGEMMSMYAAS
                     NISLAVDQFKNRGYASLKGLILNAKNVENERELVEKLADEIKSEVFHYIPRNKIVQQS
                     ENNGRTVIEEDENNEMSEVYIELANKIMKSN"
     gene            5207..6097
                     /locus_tag="PC592_003110"
     CDS             5207..6097
                     /locus_tag="PC592_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4057049.1"
                     /translation="MKLKKLCSVFLLSSLILTGCSKASDGEAKEINNNVNVVSATVAA
                     TQVLDKLDATLVGIPTTKSDLPEKYKNLPEVGQAMNPDLEIVASLKPDVFIVDSMFKE
                     NVEKSMKEYNLDTFYFETGTYTQFLKSIEDLGEKINKQSEAKKLIDELEGVEQSVAEK
                     AKKQDKKPKVAILFGGGNNFMLATKSSYLGDLVKTVGAENITDNLTDNVESDYIQFSL
                     EQILKENPDYILRFAHGNIEETKKAFDDSFDKNPAWATLDAVKNGKVIDLDSSIFNVS
                     ANIHVKDSINKLGDILYGDK"
     gene            6114..7094
                     /locus_tag="PC592_003111"
     CDS             6114..7094
                     /locus_tag="PC592_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF4057050.1"
                     /translation="MDNKKILLIVTGLITIIVLLILFSTIGSVNLSLREIFDALINEN
                     NPMVTTIVYKMRLPRNILAALVGANLAVSGLLLQAVMKNPLADPGITGISTGASVAAI
                     IILLLFPQYTNILPIVAFIGGLISCAVVYLMAYKNGLRPERIILAGVAVNTILGGVIS
                     YLSTMYSERIQSAMLWLNGSLATKTWLDVNMLIWYSIVGLIGAIFLIRSANVLQLGDD
                     AATNLGFNVNKSRFIISLVAIFLAGVSTSIVGVISFVGLIVPHITRMLLGSDHKYTIP
                     FSIILGSIVLLIADTLARTIGGSIEIPVGVIMSIIGGPFFLYLLRKRGSY"
     gene            7094..7888
                     /locus_tag="PC592_003112"
     CDS             7094..7888
                     /locus_tag="PC592_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057051.1"
                     /translation="MFNVKNIKIGYEDKIIIDNLSVSIKKSEIVSILGPNGSGKSTLL
                     KSLSRILKIKQGDIYIGKKNMKVMSNKEISRQVALLAQHNVSLKDIKVKDLIYYGRMP
                     HKGFFEGKNRNDDEIVTWAMRNTGLESYKDKLVSNLSGGERQRVWLAMALCQKPDILL
                     LDEPTTYLDISHQLELMELVRDINKKFKMTIIMVLHDINQASKYSDRLIIMNNGSIVA
                     DGHPNKVISEKIIKEVYKVKCDIDIDPISKKPRIHPIMLCRRTSSI"
     gene            7987..9264
                     /locus_tag="PC592_003113"
     CDS             7987..9264
                     /locus_tag="PC592_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
                     /protein_id="HDF4057052.1"
                     /translation="MYTLDVLNRLKDIDCDKDIKSLSYAVFPGTHCPLFGVVLTASYI
                     RNMALVVVGTNECTYYSKNFAYHRQFGNDSVYSVVLKDKDIVFGAEKKVVEAVKYISE
                     IGEFDAIMIVTTCVPELIGEDYNALSSELEDMLRIPVLTVNTEHYTCNSHILGMTRAL
                     RSLSSVMESYKKKEGVNILGHRQENVEDTELVKLLVKKDIKINCVIPSKCTIKDIKNA
                     SSAKLNIVTDMIALDLAEDMKNKFGIEYVYFDKNMKESIIIENYNKLCKILDIDIQDE
                     VSKQRQRYNSLLNECRYLLDGKKLIYGNTPMMAFETVDFLTELGLVPEFIQVRELYEQ
                     DNLFKDNIIKKGYNPYVSRIANIAPLRSLYENINADIYIGHENPMLLREKGLMQITLD
                     EHAQKIGFELPIGIMKTLIKLFDVEKSTRREVI"
     gene            9266..10210
                     /locus_tag="PC592_003114"
     CDS             9266..10210
                     /locus_tag="PC592_003114"
                     /inference="COORDINATES: protein motif:HMM:NF012375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase component 1"
                     /protein_id="HDF4057053.1"
                     /translation="MEIYRYFPNPSDRMGIIFIVSSINEACVIEFGPSGTTHYAIEAI
                     GSLNGEDKAKIYSTHMSESDVTFGNYDRLEKAIIEVDSNIKPKYIFVMASSVSSIIGT
                     DIIGICNILKESVNCRLIPITTGGLRDDYNQGVEEFLYILAKEVVKESSEKFDSYNII
                     GCTIDQFNFLADCEEIKRMMKAFFKKEVNVTFTSYTSIDEIENASKSSLNIVLRKEGI
                     KAAIFMKEKYSIPYVYKKPYGIKNTEEFINEIQKVTEWDLDTNTYDDEISNIKRYIFN
                     VKRKLYFYEGSKKCAVFGDYDTALGFRDLLEELGLKID"
BASE COUNT         4073 a         1148 c         1653 g         3452 t
ORIGIN      
        1 tttgaaaaat ttaaatatat aaaactataa aggttacaat tttggaaata gatgtaaata
       61 tatgttttat agtataataa gaagtaatat accatctagt aaaaataatt aaataaattt
      121 aatttatgag agggataact atggaaaata atgattttaa attaacaata tgtatatttg
      181 cttttgtaac tggagtagta gtattattct gctgtatagg tttaggtgaa tttagtgtag
      241 agcatattat tcaacaaaat ggtggaacca tggatactga ccaatataat atttatctag
      301 accaatctat ttctcaatat agaaattttg gttctatatt agcgttgtta ggaggactag
      361 ggatattgtt tgataaatat atcagaaaat actaaagatt atgttttgtt taaaataaat
      421 ttttatgagg agataaaaaa tggcaacaga aatatttact gtaaaaatta cgcctataga
      481 agcacaaaaa ataataaaag aaaatcttaa tgcagattta gtttttagtg attcttataa
      541 tttaggaaat gataaattta tactgattac aacttttgag aagtattatg caagaaacaa
      601 tagtgatgca gggttaatcg tagtttatga aaatacaaca ggaaaaacag ttattaaagc
      661 tatttcaaca ggtagtgcaa ttggagtttt aaaaattgac tggggtgcag gtggaaattt
      721 acttaaaagg gtaaaaaata tacttgctga ttatattatt taattatttt atctaattga
      781 taacatgtca agaaaatctc gtaaaagagg ttaagaacat tcttataata tatagataaa
      841 caagaattta aaggtaaagc ttttaatcta taataaataa tattaatata gtatgaataa
      901 aaagtaggag catattaata taatgcccct acttttttat tattaaaatt gtttataata
      961 ttaaaactac attaaaatac agtctaaatt taacaaataa atggtgtaga aatatgtact
     1021 ttttttaatt tattatattc ttttaaattg aattttttca tctgaacata aagtctcaaa
     1081 tttgtatgcg tctgtcatat cataaaaacc aaaaaatata aagccatcac gagaagtaaa
     1141 ttcatattgt atattttcaa ttttcaatat attttctacc tcacttattt tttcactata
     1201 tataatttct atcatataat ttatcattgt agaatccctc ctattaatat gaaaatatcc
     1261 aaatatataa taacatattt agatgatata atagtatcca aataaaaaat aaagttattt
     1321 cattattgaa tgaagaatta aaatgaagat aaataaagta aatattggtt ataatagatt
     1381 aaaaaatggc tatgtacact tgtaatttta gtcataggag gttaaagttt tatgaaagaa
     1441 gtcgtatata tatggggtat tctagtcagg aattgtttaa taataagata atactataaa
     1501 aatttgagta ttatataaaa agtaagaagc cataaatgat ataagcatta tctatagctt
     1561 cttatttctc attgattaag attatataaa aacaataact atattttttg tttaagtttt
     1621 aatacttgtt ttactatatt tgttgagtgg tcagaaattc tttctagatt agtaagtaaa
     1681 tcaagataaa gtacaccagc atcaattgta caacttccgt tatttagtct aatcatatgt
     1741 gaatttttaa aagttttttc taaataattt acttcatttt caacttctaa aactttattt
     1801 gctaactcaa aatctttgac atctaaaact attaaggcat ccttgaaatt agtaattgtt
     1861 ttattatata tttcatatat ttctcttatt gcactatcag aaaaactaat attcatttcc
     1921 ttaacactca tggccaattc agctatattt tccgcatggt cagagactct ttcaatgtca
     1981 tttacagtat taaaaagtaa atctgttcta aaacgttcat catctctaag aggttcttta
     2041 gaaagtttta ataaatagtt taatatatct ttctgtaact tattgacaac tttttctgat
     2101 tcaaaagctt tattaatatc ctcattgctc ttatttaaaa atcctgcaat tgaatgttcc
     2161 aaagagtttg tagctttatg acccattctt acaacttctt gtacagtatt accaagtgct
     2221 atagatggag tactaaacat cctttcatct aagtatttag tgttatttac tatttctgat
     2281 tcagtttctt taataggtat aagtctattt gctaatttaa ctatgtattt agaaaatggt
     2341 aataatatta taacatttgt aagattaaat aaagtatgtg catttgctat ttgtctagct
     2401 gtatcagttg ggtcaaaatg agtaactata gctgatatag gtttatttaa aataagcata
     2461 aatattattg taccaatgac attaaaactt aagtgcatta cagctgcacg tcgagcattt
     2521 ctacttgcac caacacttga taaaagtgaa gtaacacaag tacctatgtt atctccataa
     2581 agaataggca aagcagatga tagaggaagt attccttgag aagctaatgc tattaacata
     2641 cccatagatg cacttgaact ttgaacaata ccagttatgg cgaatcctgc caatatacct
     2701 aatataggat ttttactaaa atataaaagt gcatcagtga atgctttata ttcagcaagt
     2761 ggagctactg catctttcat aaactccatt cctgtaaata atataccaaa acctataagt
     2821 atttcagata aatgctttgt tttttgattt gatgtaaata aatagaataa aatacctata
     2881 cctagagcaa ttggtgcaat tccttcaaga ttaaatgaaa ctaattgagc agtaactgta
     2941 gtacctatat ttgcccccat tattacacca atagcttgac ttagattcat tatacctgca
     3001 tttacaaatc ctacaaccat aacagtagta gcacttgagc tttgtataat acctgtaaca
     3061 actgtaccta ctagtacacc cataacaaca ttacttgtta agagttcaat aatttttttt
     3121 aatttgtctc ctgctgattt ttgtaaacct tctcccatta aactcattcc ataaagaaaa
     3181 agtccaagtc caccgataag gctaattact atattcacga tatttcctcc cttaagaaat
     3241 taatgatttt tttatctgaa ttataaactt tattaactaa aatttattgt ttccataata
     3301 tagaataaca aattttgtca ataagaatat taatgttttg ttaagtatac gttaagagaa
     3361 tgttaaattt ttaagttgtt gttaatttta gaaaatttat gatgtatagc aatttaaata
     3421 cttggactta gatttttagt attttatgta caaacaattt aacaaagaat taactataat
     3481 tgtaaaaaat atgtaaaaaa acagcatctt tttagaatga tattttttag ttataaatat
     3541 tcttatattc aattggtgta aggttattaa actttttaaa aaccatacta tagtaatttt
     3601 gactattgaa tccaactagt accgcaacat ctaaaataga caaatctttt tctaatagat
     3661 actttttgct tttttcaact ctaactttat ttaaaaaatt agtaaaagta tatccacttt
     3721 cttttttaaa caaagaacaa aaataacttt tattaagttg taagtcattg catatatcac
     3781 ttactgttat atcttctgag tagtttttgt gaatataatc tatagttttc tttacataaa
     3841 aactaagcgc tggtctatgc ttcattttat caaggcatat ttctgataaa agatttgata
     3901 tataatctaa acatgataaa ggtttaaatg ggatattaga aaactctata tcattattga
     3961 tgcatgattt aaaaggacct acaataaagt aaccacttga tacatcaaac ttatgtatag
     4021 gcataactaa aaaatgtaag tcatcacaaa aacttaacat tatatagaat agatttttat
     4081 tagatataaa atctgtacta tttatattgc taaatatatt taaacttgaa aaatatgttt
     4141 ctaaagtagg gtcatatcca atactacaaa tctcttttaa atccttacta aatacttttg
     4201 ttggaatatt acaacagtca aaaaaatcat tgatgatgag ttctatatca tctttaaaat
     4261 ctttcaaaaa atcacctcat ttaaatttat acaaatattt ttataaaaaa acaaatatag
     4321 ttaagaataa aaaaaatata tcaattaaaa tagttattgc gaatgataat taatttcgtt
     4381 aaataatatt atgatgtaag agaggtagaa agtcaatgaa aaaaatagct atctatggga
     4441 aaggaggaat tggaaaatca acaacaactt ccaatttatc ggcatcactt tctcatttag
     4501 gatataaggt aatgcagata gggtgtgacc caaaatctga ttccacaaaa aacttaatga
     4561 aaggaaaatt tataccaaca gttcttgatg tattgaaaga aaaaaaggaa gaattaaagc
     4621 ttgaagatat agtgtttgaa ggttatggag gagtattatg tattgaagct ggagggccaa
     4681 ctccaggtgt aggatgtgca ggaagaggta taatagcagc ttttgaaaaa ttggaagaat
     4741 taaaagcatt tgaaatatat aatccagatg tagtaattta tgatgtttta ggagatgttg
     4801 tttgtggggg cttctcaatg ccaataagaa atggatttgc aaatgaagtg tacatagtaa
     4861 cttctggaga aatgatgtca atgtacgcag caagtaatat atctttggct gtagaccaat
     4921 ttaaaaatag aggatatgcc tctttaaaag ggcttatatt aaatgcaaaa aacgttgaaa
     4981 atgaaaggga attagttgaa aaattggctg atgaaataaa aagtgaagtt tttcattaca
     5041 taccaagaaa taaaattgta cagcagtctg agaataatgg acgaactgtt atagaagaag
     5101 atgaaaacaa tgaaatgtca gaagtatata tagaacttgc aaataaaatt atgaaaagca
     5161 actaaaaaag tatatttaaa attaagttta ttatggagga aattttatga aattaaaaaa
     5221 attatgctcg gtatttttac ttagctcatt aatattaaca ggatgctcaa aagcatcaga
     5281 tggtgaggct aaggagataa ataataatgt aaatgttgtt tcagctacag tggcagctac
     5341 acaagtatta gataaattgg atgctacgtt ggtaggaata ccaactacta aatctgattt
     5401 accagaaaaa tataaaaact tgccagaagt aggacaggca atgaatccag acttagagat
     5461 tgtagcatct ctaaagccag atgtatttat agttgatagt atgtttaaag aaaatgttga
     5521 aaaaagcatg aaagaatata atttagatac tttttatttt gaaactggta catatacaca
     5581 atttcttaaa agtatagaag atttaggtga aaaaataaat aaacagagtg aagcaaaaaa
     5641 acttatagat gaattagaag gagtagaaca atctgtagca gaaaaagcaa aaaaacaaga
     5701 taaaaaacca aaagtagcaa tcttatttgg tggtggaaat aattttatgt tagctacaaa
     5761 aagttcatat cttggggatt tagtaaaaac agtaggtgct gaaaatataa ctgataacct
     5821 aacagataat gtggaatcag attatatcca atttagttta gaacaaattt taaaagaaaa
     5881 tccagattat atacttagat ttgcacatgg aaatattgag gagactaaaa aagcatttga
     5941 tgattctttt gataaaaatc ctgcatgggc tacattagat gcagtaaaaa atgggaaagt
     6001 tatagattta gattcaagta tatttaatgt atctgcaaat atacatgtta aagattcaat
     6061 aaataaattg ggagatatct tgtatggaga taaataaatt ttaggtgaat aatatggata
     6121 acaaaaaaat tttattgata gttacaggtt tgataactat aattgttttg ctaattcttt
     6181 tttctactat aggaagtgta aacttaagcc ttagagaaat atttgatgca ctgataaatg
     6241 aaaataatcc gatggttact acgattgtat ataagatgag attacctaga aatatattgg
     6301 cagcattggt tggagcaaac ttggctgttt ctggtctatt attacaagct gttatgaaaa
     6361 atccattagc agaccctgga ataacaggga tatcaactgg tgcaagtgta gctgctatta
     6421 taatattgct tctatttcca caatacacaa atatattacc aatagttgcc tttataggag
     6481 gtcttatatc ttgtgcagta gtatatttaa tggcatataa aaatggtcta agaccagaaa
     6541 ggattatatt agctggggta gctgtaaaca ctatattagg tggagtaata tcgtatttat
     6601 caactatgta tagcgaaaga attcaaagtg ccatgctgtg gttaaatggg agtttggcaa
     6661 caaaaacatg gttagatgta aatatgctta tatggtattc catagtaggt ttgataggag
     6721 cgattttcct tattaggagt gcaaatgtac tacaattggg agacgatgca gctacaaatc
     6781 taggtttcaa tgtaaataag agtagattca taatatcgtt agtggcaata tttttagctg
     6841 gagtttctac ttctatagta ggggttatta gttttgtagg tctaatcgta ccacatataa
     6901 cgcgtatgtt gcttggtagt gaccataaat ataccattcc atttagtata atactaggaa
     6961 gcatagtttt attaattgca gatacattag cgagaacaat aggaggttct atagagattc
     7021 cagtgggtgt tattatgtct ataataggag gtccattctt cttatattta ttaagaaaga
     7081 gaggaagtta ttaatgttca atgtaaaaaa tattaagata ggttatgaag ataagattat
     7141 catagacaac ctaagtgtaa gcattaaaaa aagtgaaata gtctctatat taggaccaaa
     7201 tggttcagga aaatctacac ttcttaaatc attgtctaga attctgaaaa tcaaacaagg
     7261 tgatatatac attggtaaaa aaaatatgaa agttatgagt aataaagaga tttcaagaca
     7321 agtggcatta ttggctcaac acaatgtatc attaaaagat ataaaggtaa aagacttaat
     7381 atattatggg agaatgccac ataaaggttt ttttgaaggt aaaaacagga atgatgatga
     7441 gatagtgact tgggcaatga gaaatacagg tcttgaatca tataaggata agttggttag
     7501 taatttatct ggaggtgaaa ggcaaagagt gtggttagca atggctcttt gccaaaaacc
     7561 agatatactt ttattggatg aaccaacgac atacttagat atatcacatc aattagaact
     7621 tatggagctt gtaagagata taaataaaaa atttaaaatg actataatta tggttttaca
     7681 tgatataaat caagctagta aatacagtga taggcttatc attatgaata atggttctat
     7741 agtagcagat ggacatccaa ataaggtaat aagtgaaaaa ataataaaag aagtatataa
     7801 agtaaaatgt gatatagata tagacccaat tagtaaaaag cctaggattc atccaataat
     7861 gctatgcaga agaactagta gtatatgaaa gtataatatt ataaataatt aaaaagcaaa
     7921 agttattatc tatgtaaatt tataagtttg aatttatata gataatagaa gtagaaagga
     7981 aaatatatgt atactttaga tgtattaaat agattaaaag atatagattg tgacaaagat
     8041 ataaagtctt tatcatatgc tgtattccca ggaacccatt gtccattgtt tggagttgta
     8101 ttgactgcat catatataag aaatatggct cttgtagtag taggaacaaa tgaatgtact
     8161 tactatagta aaaactttgc atatcatagg caatttggca atgatagtgt ttattcagta
     8221 gtactaaaag ataaggacat agtttttggt gcagaaaaaa aagtagtaga agctgtaaaa
     8281 tatatttcag aaattggtga atttgatgca ataatgatag taactacatg tgtaccagaa
     8341 ttaataggtg aagattataa tgctctgtct agtgaattag aagatatgct taggatacct
     8401 gttttgacag ttaacacaga gcattatact tgcaattctc atatacttgg gatgacgaga
     8461 gctttaagga gtctatcatc agttatggaa agttacaaaa agaaagaagg agttaatata
     8521 ttaggtcata gacaagaaaa tgtagaggat acagaacttg taaaattgct cgtaaaaaaa
     8581 gatataaaaa taaactgtgt aattccatct aagtgcacta taaaagacat taaaaatgca
     8641 tctagtgcta aattaaacat agtgacagat atgatagctt tggacttagc agaagatatg
     8701 aaaaataagt ttggtataga gtatgtatat tttgataaaa acatgaaaga gtcaattata
     8761 atagaaaatt ataataaact ttgtaaaatt ttagacatag atatacaaga tgaagtatca
     8821 aagcaaagac agagatacaa ttcattattg aatgaatgta gatatctgtt ggatggtaaa
     8881 aaattgattt atggaaatac accaatgatg gcatttgaaa cagtcgattt tttaactgaa
     8941 ttaggactgg ttccagagtt tatccaagtg agagaacttt atgaacaaga taatttattt
     9001 aaagataata taataaaaaa aggatataat ccatatgtaa gtagaattgc aaatatagct
     9061 ccacttagaa gtttgtatga aaatataaat gcagatattt atatagggca tgaaaatcca
     9121 atgttattaa gagagaaagg gcttatgcaa ataacattag atgaacatgc acaaaaaata
     9181 ggttttgagc ttccaatagg aataatgaaa acattaatta aattatttga tgtagagaaa
     9241 tctacaagaa gggaagtgat ttaatatgga aatatataga tattttccaa atccttctga
     9301 cagaatggga ataatattta tagtatcatc aataaatgaa gcatgtgtta tagaatttgg
     9361 accatcaggt acaactcatt atgctataga agcaattgga agtttaaatg gagaagataa
     9421 ggctaaaatt tattcaacac atatgagtga aagtgatgtt acttttggaa attatgatag
     9481 attggaaaaa gctataattg aagtagatag taatattaaa ccaaagtata tttttgtaat
     9541 ggcttcatct gtatcttcaa ttataggaac agatataatt gggatatgca acattttaaa
     9601 ggaatctgta aactgtagac taattccaat tacaacaggt gggttgagag atgattataa
     9661 ccaaggcgta gaagagttcc tttatatact tgcaaaggaa gtagtcaaag agagtagtga
     9721 aaaatttgat agttataata ttattggatg tactatagac cagtttaatt ttttagcaga
     9781 ttgcgaagaa attaaaagaa tgatgaaagc tttttttaaa aaagaagtaa atgtaacctt
     9841 tacatcatat acatcaatag atgaaataga aaatgcttct aaatcaagtc taaatatagt
     9901 acttagaaaa gaaggtataa aagcagcaat ttttatgaaa gaaaagtata gtatacctta
     9961 tgtatataag aaaccttatg gaataaaaaa tactgaagaa tttataaatg aaatacaaaa
    10021 agtaactgaa tgggatttag atacaaatac gtatgatgat gaaatatcaa atataaaaag
    10081 atatatattt aatgtaaaaa ggaagcttta tttttatgaa ggaagtaaaa aatgtgctgt
    10141 gtttggagat tatgataccg cattaggctt tagagactta ttagaggagt taggtcttaa
    10201 aattgattaa aaaatagcta cgcacactcg tgactttagt catgagttag tagctaaatt
    10261 agtcagcata tagggaaact tatatgtaga gataggataa cacctatcca atactacttg
    10321 aattgc
//
LOCUS       DAMKOJ010000104        10302 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000104 DAMKOJ010000000
VERSION     DAMKOJ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10302
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.113"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(156..299)
                     /gene="scfA"
                     /locus_tag="PC592_003115"
     CDS             complement(156..299)
                     /gene="scfA"
                     /locus_tag="PC592_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HDF4057054.1"
                     /translation="MKNKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(365..727)
                     /locus_tag="PC592_003116"
     CDS             complement(365..727)
                     /locus_tag="PC592_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HDF4057055.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(785..1078)
                     /gene="yajC"
                     /locus_tag="PC592_003117"
     CDS             complement(785..1078)
                     /gene="yajC"
                     /locus_tag="PC592_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDF4057056.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLGV
                     GDKVVTIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(1212..2333)
                     /gene="tgt"
                     /locus_tag="PC592_003118"
     CDS             complement(1212..2333)
                     /gene="tgt"
                     /locus_tag="PC592_003118"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDF4057057.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHNFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPADREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITSIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(2412..2897)
                     /locus_tag="PC592_003119"
     CDS             complement(2412..2897)
                     /locus_tag="PC592_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057058.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKAQQNKEDEDKS
                     I"
     gene            complement(2909..3934)
                     /gene="queA"
                     /locus_tag="PC592_003120"
     CDS             complement(2909..3934)
                     /gene="queA"
                     /locus_tag="PC592_003120"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDF4057059.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLMGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLSKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGNNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(4252..5271)
                     /gene="ruvB"
                     /locus_tag="PC592_003121"
     CDS             complement(4252..5271)
                     /gene="ruvB"
                     /locus_tag="PC592_003121"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDF4057060.1"
                     /translation="MQGFEDENRIITSTMKVEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSNILDAKIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(5378..5980)
                     /gene="ruvA"
                     /locus_tag="PC592_003122"
     CDS             complement(5378..5980)
                     /gene="ruvA"
                     /locus_tag="PC592_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDF4057061.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLAESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(5973..6482)
                     /gene="ruvC"
                     /locus_tag="PC592_003123"
     CDS             complement(5973..6482)
                     /gene="ruvC"
                     /locus_tag="PC592_003123"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDF4057062.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(6794..7423)
                     /locus_tag="PC592_003124"
     CDS             complement(6794..7423)
                     /locus_tag="PC592_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057063.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDTGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            7626..7949
                     /locus_tag="PC592_003125"
     CDS             7626..7949
                     /locus_tag="PC592_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF4057064.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            8213..9067
                     /locus_tag="PC592_003126"
     CDS             8213..9067
                     /locus_tag="PC592_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057065.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEVYFILDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKFITQETIENKLESLVENRLDTLEDRLE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(9253..10254)
                     /locus_tag="PC592_003127"
                     /pseudo
     CDS             complement(9253..10254)
                     /locus_tag="PC592_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
BASE COUNT         3296 a         1836 c         1161 g         4009 t
ORIGIN      
        1 atatttttgc ataattaaac attaagaaat caaatttaat tttatataaa tagtttaaat
       61 attttatata caaacaaaaa taaaagagga tacctcctaa tgataaaaga atcacattga
      121 gataccctct tacaaacaac taaatcaata attttctatc tttcacactc ttgatttgca
      181 actgtacaag aagttttaca agctgattga caagaagttt gacactctcc acatccacct
      241 tttgcagcac tttgctttaa agtagcttga gataaagttt ttacatgttt atttttcatt
      301 ttaaacgcct ccatttctaa ttgtttccta ttgattatat cataaaacta ccttaatata
      361 aactctattt aaagttgaca cccaatacgc ctccaatgcc tcctgctgct gatattagca
      421 ataacttata aatcattcct acttcgaata caaacttttc ttgtgctaaa aacacagtca
      481 aaaaaataca tactatgtac aaaagtccta ctaaaagccc atacataagt cctttttctt
      541 tcatgtgttt tgaagtataa aaccctccta tagctgcaga aatagtagtt ataaatgatg
      601 aaaccatagt tatattatcc ccaccaatat ctgtaaatgt caaaaataag ttatacacta
      661 ataaaacagc caaagttatt atatatgcat atcctagacc tttaaaaata taattagatt
      721 ttcccataaa aaaacctcct ctcaaattaa tatatattcg agaaaaggct tttaaattac
      781 taatttagtc ttcttctatt tcttcttttt tagatttaac agttcctata gcccattttt
      841 caaatggtac tttagttcta tttggtccta attctaatat tacaacatca tcttcaactt
      901 tagctacatt agctactatt ccacctattg taacgacctt gtctcctaca cctaggctac
      961 ttctcatttc ttttaattgt ttgtcttttt tcttttgagg tctaatcatt aggaaataaa
     1021 agattgcgat tactactacc catagaccta tactcataat tatttgttgc tgtggcatta
     1081 atttttcact cctttgtaaa ttatactctt ttgtaaatca taataaatgt ttatataaca
     1141 atttactttc tctatctttg agtactattg aatattatat attaaaatga ttataattaa
     1201 tagtgcaaaa tctatatttc atatccatat tttgcaaaaa attcatttct aaaatcaagt
     1261 aatctatctt ccattatcgc ctgtcttatt tgtttcatta aatttaataa gaagtgaagg
     1321 ttgtgagtag ttattagtct tgcacccagt atttcatttg cttttataag gtgtcttata
     1381 taagctcttg aatagttttt acaagcataa caatcacatt cagggtcaag tggagtaaag
     1441 tcttcagcat aagttgcatt tctaactact actttacctt ggctagtcat tgcagttcca
     1501 tttctagcga tacgagtagg taagacgcaa tcaaacatgt ctactcctct tataacacct
     1561 tccactaaat catctggact accaactccc attaggtacc ttggtttatc ctttggcata
     1621 agtggagttg tatgctccag cacatcatac ataagtggtt ttggctctcc aacactaagc
     1681 ccaccaatag catatcctgg taagtcaata ctagttatct cttttgctga ttgctctctt
     1741 aaatctttgt acatcccacc ttgtattata ccaaataaag cttgcttatc tgtattatta
     1801 tgggcatctt tacatctttt taaccatctt gttgttcttt ctaaagaatt ttttacatat
     1861 tctctatctg ctgggtatgg tgcacactca tcaaacgcca tcattatatc tgaacccaac
     1921 gcattttgta tttccatagc tttttctgga gttagaaaat gttttgaacc atctaagtgt
     1981 gacctaaatt ccacaccttc ttcttttatc tttcttaaag gacctaagct aaacacttgg
     2041 aatcctccac tatctgtaag tattggttta tcccaattca taaaattatg aagaccacca
     2101 gctcttttta taagttcatg acctggtctc atatataaat ggtatgtgtt actaagtatt
     2161 atttgtgaac caatctcttt taattcttct ggtgtcatag attttacagt tgcttgagtt
     2221 ccaactggca tgaatattgg cgtttcaata attccatgtg gagtgtgtaa tcttcctaac
     2281 cttgcgccac tctgcttaca agtctttatc aattcgtatc ttactgcgta cataaagttc
     2341 tccttaatca tatttatttc tcattatttc ttaagatata tttgtaataa gctattcata
     2401 taatttattg tctaaataga tttatcttca tcttctttgt tctgttgcgc cttaattgct
     2461 tcttcatcat gaatactcat tatattaaga gcactcttgt cttttgttac taaaaacttt
     2521 tttatagcaa acagccctgc aatagctata actcctatta aaacatctat cataccttca
     2581 tttttaggca gtaacaacat ttttctagct atagcgtaaa gtaatgcctc aataaatgct
     2641 cctggtatat gaagagataa cattactaca agttcaacac ctatcactaa gagtaatatt
     2701 tgtgctaaaa aatcattaag ctgactgtat tgtactggat tttgaaaatc aactatatac
     2761 gctccccaca taagtcttag aacatctata gttcctaaaa atactgctat tagaactact
     2821 actgctaaaa cacgttcaaa tataaaagca atctttaata tagggttatt ctttttttgt
     2881 ttttgtaaac tatgcatcaa ttacctccct actttataat catagcatct ccaaaactga
     2941 agaatctata tctttctttt actgcctcat tatatgcatt taaaacatta tcctttccac
     3001 aaatagcact tactaacatt attagtgtag actctggcaa atgaaaatta gtaataagtt
     3061 tatctaaaac tttaaattta taacctgggt atataaatat ttctgtccat ccactggttt
     3121 ctttcatttt tccatcctca ttacaagctg attctatagt tctacaacta gtagtaccaa
     3181 cacatattac attatttcca ttttcttttg ctctatttat tttgtcagct gcttcttggc
     3241 taaccatata atattctgaa tgcatcttgt gatttaaaac atcttctact tttactggtc
     3301 taaaagtgcc taaaccaaca tgtagagtta caaaagctat atctacacct ttttctttta
     3361 ttttacttaa caattcttct gtaaagtgta atcctgctgt aggtgctgct gctgaaccat
     3421 tatgctttga ataaacagtc tgatatcttt ctttttcatc taatctagca gtgatatatg
     3481 gaggtagtgg catatttcca agttcatcca agatttcttc aaaaattcca tcataatgaa
     3541 attttataat tcttgaacct tcatctgata aatctacaac ttctccaatt aactttccat
     3601 ttccaaaaga aaatttagtc cctacttttg ctctttttcc tggttttact aaagcctgcc
     3661 aagtatcttc ctctgttctt tttaataata aaaactcaat tttacctcca gtttcaagtt
     3721 tctctcccat caatctggct ggtataactc tagtattatt taatactaaa caatcccctg
     3781 gatttaaata ttctattata tctctaaata ctttatgctc aatattgcct gtctctttat
     3841 ctaataccat caatcttgaa ctagctctat cttctatagg aacttgagct ataagttcct
     3901 gtggtaagtc aaatttaaaa tcacttgttt tcaatgttaa acttcctctc ttaaaatttc
     3961 tccagctaca ataatatcaa aaaaataact tattttccac aatattacca taatctatca
     4021 agaaattgct atttttaaca gacatcatat ccacaatata tagatatttt tccacgatat
     4081 gcacgtatta tccacaatat atagatacaa tacgcacaaa ttttatcgta tttatccaca
     4141 gtatctacag atataattac cattttgtgg atatatttga atttttagcc attttagaaa
     4201 tattttaatt taatgactat tctattttat aaatacttgc ataatctatt tttatttttc
     4261 attaggatat ggaattttta agtgttcata tgctaatggc atggctaccc ttcctctagg
     4321 tcctctattt ataaatccta attgaagcaa atatggctca tatacatctt ctattgtatt
     4381 tctatcttct ccaatagaag ctgctaatgt atccagacct actggacctc ctctaaattt
     4441 ttctattata gtcataagaa gcttctcatc tacaaaatca agacccaaac tatcaactcc
     4501 taaaagttct aaagcatctt ttgccacctt atcagttatt tttccatcag ctctaacttg
     4561 tgcaaaatct ctaactcttt ttagtaatct atttgctatc cttggagtcc ctcttgaacg
     4621 tttagcaagt tctaacgctc cattagactg tatctttgca tctaaaatat ttgatgacct
     4681 aagtactatt tttgaaagct catcaactgt ataataatcc agtttacaaa taacaccaaa
     4741 tctatctcta agtggatttg taagcatacc agctcttgta gtagctccaa taagtgtaaa
     4801 tttaggaagg tcaagtctta tgcttcttgc agatggccct tttcctatta ttatatctag
     4861 gcaaaaatcc tccattgctg gatataaaac ttcttcaaca cttctattga ttctatgtat
     4921 ctcatctata aataaaacat cattttcatt taaatttgta agtatggctg ccaaatctcc
     4981 agctctttct attgcaggtc ctgacgtaat tcttaaattt acccccatct cattggctat
     5041 tatacttgct agtgtagttt ttccaagacc tggtggtcca tataaaagca catggtctaa
     5101 ttgctcattt ctcgatttag ctgcttctat aaatatacta agttgctctt tggatttttc
     5161 ttgccctaaa taatcttcta aagtttttgg tcttaaactg ttttctatat ctatatcttc
     5221 caccttcatt gtagaagtta ttatcctatt ttcatcttca aaaccttgca tttatacccc
     5281 tcctttcgta cttttgaaaa tctactttat atattttcaa atttacataa actccttaaa
     5341 tattgtttta aaatctaaat attataaaat ccaaatatta ttttaaggat ttactcatta
     5401 tatatgtaag tgctttcttt ataatagctt ctgtattcat accatctttt ttacattttt
     5461 gaactgcctc ttttgattcc gccaaagtat agcctagagc tacaagtgca tctacagact
     5521 catcttgaga tatcaaggta ggtttttgtg ataataatgt tggttcaaac tctatgttat
     5581 ttttatctac cttatcctta agttctaaga caattctttc tgctgtcttc ttaccaacac
     5641 caggagcttt ggataacttt ccaatatctt cacttaaaat atatgcgcct aattgtgctg
     5701 gtgatgcaaa tgatagtatt gaaagtgcta ccttaggtcc tatttttgac acagatgtaa
     5761 gtagttcaaa catcttaagt tcttctctac ttacaaaacc acaaagactc atatcatctt
     5821 ctcttacaat taatttagta tatatttttg tggcttctcc cacttgtaaa ttcattattg
     5881 tattggatga tacatttatt ttatatccta tcccattatt ttcaacaact atactgtcta
     5941 tataaatttc ttctactgta ccttttatat aactatacat atttaccacc tatattcttt
     6001 agagtttttt caagtttgtt tgagtgagca tggcaaatag ccacagctaa agcatctgca
     6061 acatcatctg gttttggaac tttttttaga cttaaaaatg aagttaccat ctgttgaact
     6121 tgtgctttat ctgctctccc atatccaact acaccttgtt ttacttgaag tggagtgtat
     6181 tcatatacag gcttcccatt atgagcacat gcaagcatag taacacctct agcttgtgca
     6241 actgttatag ctgtttttac attcttgtta aagaataatt cttccattcc aacttcatct
     6301 atattgtaat tctttactat tgtatcaatt cctttatata caagttctaa tcttctcgat
     6361 atattcatat gggcaggtgt tgtaactgct ccataatcga ttactttaaa cttgctattt
     6421 ttgtattcaa ttataccata tccaactata gctatacctg ggtcaatccc caatattatc
     6481 attttttaaa attcccccta aaaataaaag aaataccaaa atgtatttct cataaaaact
     6541 tatgttctaa atcattatat cataaataat attaacaaat cataaaatgc tctatgtaaa
     6601 atataaaatc aaataaaaaa gttatatcaa agcaagattt tacctcaata taacttttat
     6661 atttagtaca aataaattat tgcattttta tatgaattaa atgtgactac aattttaata
     6721 ctaatctatc taatattaaa ttatttatta ttaacttact tagtatttaa cttgaaatag
     6781 tattaattta ctattaactt gcaaagtctt ctaatcttga ataggcctct tcttcagtat
     6841 ccataactac accttttttg atttcatctt gaactgtttt aggaagtgaa tctactctta
     6901 tttttgtttt ttctactaat gttttacttc cagtatcatc atatttatat agtgctatat
     6961 ttccattatc attttcaata gtatatttac cttttatagt aacatccatt gcttgtacat
     7021 ctttattatc actatattta gattctacca atatgatttc atttttatcc atactcttta
     7081 tttttttagt tggatattct tttttaaaat atgatactat ttctgacttt gtcttatcta
     7141 ataatgactc tggaactatt cctgccattg taagtgttct cttatagttg gtttcatttt
     7201 cgccttcact ttgaagccaa acttcacaat ttttatttaa tccaaaagct tcttttgact
     7261 tttcattcat attcgcacta gtacttacaa cttcaccagt ttgaactcca ttgtgtttta
     7321 atcttgtccc tatataaact ccactactta atacaaatac tccaactagt attaaggcag
     7381 atattttcca aggaaataat tcttttttct tcttttcaaa cattgattac gcctcctttt
     7441 tctattattt tctccaagct gtaagttttt atacaattta ggtaaatttt agaagaaaat
     7501 atatttatat ttcaaattac tctaagaata gatattttct aaatggtagt tttctcttaa
     7561 tagttatatt cttgtaatta tatggacata atttataata aataatcgtt taggaggtaa
     7621 taactttgga aagaataaac tgtaatgtaa ttaactgttc acataacaac agtcatatat
     7681 gttatgcaga taaaattttt ataaatggtg aaaaagctca caatgacaga catacttgtt
     7741 gtagttcatt tttagatgaa tctatttata gcaatctatc tagcaatgtt aataatagaa
     7801 attgtgagga attagtttgt actgtaaaaa attgtaaata caataaagat ggtagtttat
     7861 gtacacttga taatatattg gttgctcctg aaactgatag agtgaacctt tatattgaaa
     7921 catgttgctc tagtttcgaa tgtaaatagt catagtataa atataagggt gtcaaattta
     7981 attaaactaa catagtgtag agtatctaca actattagtt tgattatact tgacaccctt
     8041 attttaaata aaattttatt attataaaca tgtttataat gttctaactg taattaaatt
     8101 tgataaattt ctataaattg atataatcaa tatgtaaatt gaatttagta aattaatcat
     8161 aaaaataaaa tatcgagtat atagtgttat actaactaga aatgaggtgc ttatgagtac
     8221 attttatatt caatttcttt attttgtaat ttatagtttt ataggatggt gttgtgaaac
     8281 tacatattgt tcagttttac aaaaacaatt tgtaaacaga ggttttttaa atggtccatt
     8341 ctgtcctata tatggatttg gagcattagc aatagttgct actttgactc cttttgtaca
     8401 caatattcct ttgttatttt tgtttagtat aattataact agcataatgg agtattgtac
     8461 gagctttatt ttagaaaaaa tatttaatat gacttggtgg gattattcta aacacaaatt
     8521 caatattcat ggaagagttt gtctggaaaa ctcacttatg tttggtgtat tatcactgat
     8581 tgtaatgctt atagtacatc ctattgtagt agattttata aactctatct ctaaaaatgt
     8641 gctatttata tttgctatat ctatagaagt ttattttatt ttagatttag taattacagt
     8701 ccatacaatt ttacaattaa atggtaagtt aaaacaaatc aatcttataa ttaaggaatt
     8761 aaaagataag aaagaatact acaaatttat tacacaagaa actattgaaa acaaacttga
     8821 atctttagtt gaaaatagac tggatacttt agaagatagg cttgaaatac ttaaggaaaa
     8881 agaaaattat cgctatgcta aaaatcgtat tgatgagcta aaaaataaac ttaatacttt
     8941 gctgtctaac cacaaattac ttcatagacg tataatcaaa gcattcccca atataagctc
     9001 taataaacat acagatattt taaataaaat taaagaaaat attaaatcaa taaaaaaaga
     9061 taaataatca aataaacaca taagttcaat aataaaaata ctaatacata agattaaggt
     9121 ttagaatatt ttttgtaaaa tactctaaac cttaattaat atactattat ttttaatctt
     9181 aatttttaat tttagtttat ttcactttta actcagtaaa tctgagtgtt taaacttcaa
     9241 tacactgata tgctatccca tcaatatctc aactgattcc ctaagtgtgc taatctctcc
     9301 cacatttcca gggaaaatta tatatggcat attaggaaat ttactttctt tgcctgtcat
     9361 ccatactggt ataccaggct ttatttgtcc cattactgta gcttttttta ctcttagtgc
     9421 tttagtgcca acatcactag aagtaattcc acctttagct ataataaagt tgggtcttac
     9481 attaagcata ccaattatac tggtaactgc atctgatatt tctacagaaa tcataagctg
     9541 tttatcttta tcattcgtat ccaggtcaaa acgctctcgt ctagtataaa cagcaacagt
     9601 tttaccactg cttatttttt tctctacaac ttttataact ctttttacct cattttttag
     9661 accattttcc tgaagaacta agtgttgatt aaattcaata aattctattg gatatttaca
     9721 atttttaagt tcttctaact gttgggtagt cttatttaca tgtgaaccaa caagtataat
     9781 tccaccatta gtattacctt ttgacactaa ctcatcctta gtaagcagtt ccttatcact
     9841 cactccacca agtacttttg ttatggcagc agcgcttcta aacataaatt ccttaccact
     9901 atttactgct cgtataaatg caattgtaaa tacctttaca tctacatagt cggttgcatt
     9961 tacaataatt ttattgaatc cttcagccat tttaagtttt tctgttatgg cttcaatatt
    10021 tagttctcta agttcttcag aagaaatata tatcatatca ctagatttgt actttccatt
    10081 tgtcttttct tcacaccact cacctatgtg ggatgatttg tatccaaaag atttatcctt
    10141 tgcaaattca gtcattcctg ctggtacaag tatttctcct tctttaacat aatgtacatt
    10201 atctatagta aacctaccac cttctttaaa aaatggcatt attatttcac cctgaacctc
    10261 ccatgactaa agtcacaggg ttcctgcttc acagaatttt gc
//
LOCUS       DAMKOJ010000105        10264 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000105 DAMKOJ010000000
VERSION     DAMKOJ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10264
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.114"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            163..1056
                     /locus_tag="PC592_003128"
     CDS             163..1056
                     /locus_tag="PC592_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF4057066.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREINKADINVSKYIKYAD
                     LASKNNVQVNWKYVASIVAVLNKNKLKNVKDSQIQEVSDLFVKNFSKNNKVNKLSYVL
                     DELKFNNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKSNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            1500..1991
                     /locus_tag="PC592_003129"
     CDS             1500..1991
                     /locus_tag="PC592_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF4057067.1"
                     /translation="MYENNKVIYNFERCEKLEKTLYLSQFNTYKNFKLTSKKTVINSF
                     ETYVCNMNIRSISLVDTIECISLEDEQLTGKKLILVGDIDTDVILDYVANKRNRNSSK
                     KNILKLKIPFSTFIQIPRKIENKDKINLKYLIQDISSSILDDNNLFISVTAIISYENS
                     SQI"
     gene            2022..2969
                     /locus_tag="PC592_003130"
     CDS             2022..2969
                     /locus_tag="PC592_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057068.1"
                     /translation="MRITKTTFNDVFSNDTNGSILKVEKYVDKKCASVFDILTYTIIV
                     TNVSRYKTGNIFFKDYISKYIEFVNNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNIDKFPTRISIESNRVYTNINKIVFKQLNISN
                     TLKAPKNLKDILKVNANSKILDVKPIKNPTNKGNNLKSCNLIVFGSVDVEVDYSCKNR
                     SKFKTVNKSSDIQKDKHYSNDIQNNNKTISDCKRQISIGNNKVKKITKTFGFSCFICS
                     PVGIVYEDMKNINIKIEHTSINELNPDELFINTSLLLYY"
     gene            3259..3801
                     /locus_tag="PC592_003131"
     CDS             3259..3801
                     /locus_tag="PC592_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4057069.1"
                     /translation="MKICITVGHSILKGGKSTGASGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDIIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGN
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            4130..5623
                     /locus_tag="PC592_003132"
     CDS             4130..5623
                     /locus_tag="PC592_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF4057070.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLEYNIPSRVQIEVIPKLLNGQNLV
                     VKSKTGSGKTASFAIPLCENINVEYNNIQALIVVPTRELALQVKDEISSIGRLRKVRC
                     SAIFGKQPIKEQIAELKQRVHIVVATPGRIIDHINKGTIKLEDIKYLIIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVGLFSATIDEEIKYICEKYIPDYSVINIEENKSDTNQRTR
                     QIDDKIIKTNEREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKKQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKRNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKE
                     ILKEVSKRKKADKNSYKGKDIKLNTESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKHKEIPIKKKMVKVKRDIR"
     gene            5862..6626
                     /locus_tag="PC592_003133"
     CDS             5862..6626
                     /locus_tag="PC592_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4057071.1"
                     /translation="MAYFNYNNKQCYYNEIGDGTPLLFLHGNTASSKMFNEIINFYKD
                     EYKVILIDFVGHGKSQMVDKFAADLWFDEAMQVICFLEVMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWER
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDDFVSLISNDFFENTFSSLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(6911..10090)
                     /locus_tag="PC592_003134"
     CDS             complement(6911..10090)
                     /locus_tag="PC592_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF4057072.1"
                     /translation="MKIDMIYKLIRRNTEPSRWARGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSNGKNIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSSTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINMDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYDPNIHYFADED
                     EKLVDIIEEYGTNLSYSFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPIRFDLKNIEDKIVLCSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQVLSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DSNICCDVKYIYDDEDKKFVLPNIQKETTIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSDKFKLKKIYNASSIKASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMGTSKNNKIHKNKALYIN
                     DMIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGSKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPLALV
                     TASVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKIKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSIDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIIDLFN"
BASE COUNT         4067 a         1053 c         1446 g         3698 t
ORIGIN      
        1 aactattttg tatgatagaa aactatatat tataacaata gtagtgcttt taattaaata
       61 tatttcataa atcttcataa aatcttcaaa atttcgtaaa gaatatgtca caaaagtaag
      121 gtatattata ttcagcagat aatataaggg aggacaatat ttatgaagaa taaaaaattc
      181 attgttataa tactgataat atcgatttta ataggtgtat tagtgaagga atattcatct
      241 agagagataa ataaggctga tataaatgtc agtaagtata taaaatatgc tgatttagca
      301 agtaaaaaca atgtacaagt caactggaag tatgtagctt ctattgttgc tgtgttaaat
      361 aaaaataaac taaaaaacgt taaggattca caaatacaag aagtatcaga tttatttgtt
      421 aagaattttt ctaaaaataa taaagtaaat aaattaagtt atgttttgga tgagttaaaa
      481 tttaataata gacaaaaaag attggttgat aattatatag acaaccttaa agattatggt
      541 ataaaaccag aaagattgaa atctgataca aaatatatga agtttattga cgaaattaag
      601 acagaagcaa tacaaaatta taaggattat aaaatacttc catctataac cattgcacaa
      661 gccataatag aatctagctg gggtaagtca actttggcaa aacaatataa taatctattt
      721 ggtataaagg ctgacgctta ttggaaaggt aagtcagtga ctttagaaac gaaagaacat
      781 ttagatacaa ttatagatga taaatttaga atatatgatg ataaaaatga atctataaaa
      841 gaccatgcaa aatttttagc cacaaataaa agatataaat cgaatggtgt atttgatgca
      901 aaaacatata tatatcaagc taaagcattg gaaaaggcag gttatagtac tgcaaaggat
      961 gaaaatggaa atagcatata tgcagctcgt ctaatagaat taattcaaca gtataatctt
     1021 caattaatag acagtgaaat tcaaagtgaa atgtaacttt gattaaactt ttattgataa
     1081 ggctatgatt tttaaaatca tagccttatt ttgatatgtt ttcacttgta attattaaag
     1141 cgatattatt atctttcaaa atttctttta cagtacaaat caaattatct aagttaaaac
     1201 ttggagttat ttataaaagg attatttatt ttatataaat tttgcattta aataactctt
     1261 atttctttaa ggttgacagt tagtctataa aaattataat tccttataaa aaagtcaata
     1321 gatatataca ataaaaaatt ctcaaaaaga cttttacttg caaattgaaa ttaatgaagt
     1381 aaaaaagtat tctttattaa aagtagatgg caactatata gtgaataata aaaaatggta
     1441 atttgaaata atttttatga atagtattaa tatatagata cagggagatt gatgcgatta
     1501 tgtatgaaaa taataaggta atatacaact ttgaaagatg tgaaaaacta gaaaagactc
     1561 tttatttatc tcaatttaat acatataaaa attttaaatt aacttctaaa aaaactgtaa
     1621 taaattcatt tgagacatat gtttgcaata tgaatattcg cagtataagt cttgttgata
     1681 ctatagaatg tatatcatta gaagatgaac aactgacagg aaaaaagtta attttagttg
     1741 gtgatataga tactgatgta atattagatt atgtagccaa taaaagaaat agaaattcta
     1801 gtaaaaaaaa tatacttaaa ttaaaaatac cctttagtac atttatacaa atacctagaa
     1861 agatagaaaa taaagataaa attaatttaa agtatcttat acaagatatt tcctcatcta
     1921 ttttagatga taataattta tttattagtg ttactgcaat tataagttat gaaaatagct
     1981 ctcaaatata gtaatattta aattatagaa aggtggatgc aatgagaata acgaaaacta
     2041 cttttaatga tgtattttca aatgatacaa atggaagtat tttaaaagta gaaaaatatg
     2101 ttgataaaaa atgtgcatct gtatttgata ttttgactta tactattatt gttacaaatg
     2161 taagtagata taaaactgga aatatatttt tcaaagatta tatttctaaa tatatagagt
     2221 ttgtaaataa tactgtaaaa gttaatggta ttataaagcg tggattagac ccacaacaag
     2281 gtttttatat agggagaata gatgcaagtt gtaaaaaaat aatatctttt aaaagtgtag
     2341 ttttaccaaa ttcggcacat aggattataa agaatagtgc caatatatac tattactaca
     2401 agtgtaatat agataaattc ccaacaagaa tatcaataga aagtaataga gtttacacta
     2461 atataaataa aattgtattt aaacagttga atataagtaa tactttaaaa gctcctaaaa
     2521 atctaaagga tatattaaaa gtaaatgcaa atagtaaaat acttgatgtt aaacctataa
     2581 aaaatcctac aaacaaaggt aataatttga aatcatgtaa ccttatagtt tttgggagtg
     2641 tagatgttga agtagactat agttgtaaaa atagaagtaa gtttaaaaca gtaaataaat
     2701 ctagtgatat tcagaaagat aagcattata gcaatgatat acaaaataat aataaaacta
     2761 taagcgattg taaaaggcaa ataagtattg gtaataataa agtaaaaaaa ataacaaaaa
     2821 cttttggatt ttcctgtttt atttgttcac cagttggaat tgtttatgaa gatatgaaaa
     2881 atataaatat aaaaattgag catacatcaa taaatgaatt aaatccagat gaattattta
     2941 taaacacatc gcttttatta tattattagg tattttaaat ctaaaactta aaattattaa
     3001 acgagcattt gattaaagag aagtatatat tgatatattt attttatgtg taaatgatta
     3061 attaaataat tataagtaat aagtatagta taatatttaa aaaatatgta tttatgataa
     3121 aataagacaa atatgttaaa aaaatgataa tcacggagaa cttttacctt ctccaattaa
     3181 tatattatta ttagtaataa ctttaagatt atattactat tatataaaaa ttggcttaaa
     3241 agaaggtgaa aaaagtaaat gaaaatatgc ataacagtag gtcatagtat actaaaaggt
     3301 ggtaaaagta caggtgcaag tggtatagtt gatgaataca attataacaa aaaattagct
     3361 cctatgttag ctgagatgct tataagtcaa ggtaatacag tagatataat aatttgtcca
     3421 gaaagacact ttatgtcaga aagagaagaa tttttctata gagttccaaa agtaaacagt
     3481 ggtaaatacg atttattagt agagctacat ttaaataaag ctgatggaac acaatgtggt
     3541 acagaagtgc tttactatgg taatgaagga ttagaatatg ctaaaagagt atctaataga
     3601 cttggagaat tatttgaaaa tagaggagct aaaaaaagag aaaatttata tatattgaga
     3661 aatacaaatc cagttgcaat acagattgaa agttttttct gtgataatgt gaatgattgt
     3721 aacaaagcaa atgaatcagg ttatgattat atagcacgat tgattacaga aggtatattg
     3781 aataaagata taaatatgtg agattatggt gatttaggta ttgattaata cctttaatat
     3841 tagatataaa taaaatacaa tatattagta taatttaaac ttgtaaaaga tatattagta
     3901 gtttagttgt tgacaaggga tacctccttg aaaatattga tttatcagta ttttcaagga
     3961 ggtatttaaa tataaaaatt taatttattt actactaaat tatagcttta catagtatat
     4021 atttttatct tcactctaat aaataatata aaaatagtag aaccttgtat tataataata
     4081 taatgtagaa aaatacatag ataagataaa tataataagg tggtaatata tgaaatatac
     4141 atttgaaaaa tttaagttaa atgaaaagat acttaagtca ttgaagagtt tagaatataa
     4201 tataccttct agagtacaaa tagaagttat tccaaaatta ttaaatggtc aaaacttagt
     4261 agtgaagtca aaaacaggaa gtggaaagac agcaagtttt gcaatacctt tatgcgagaa
     4321 tataaatgta gagtacaata atattcaagc acttatagta gttccaacaa gagaattggc
     4381 tttgcaagta aaagatgaga tatcgagtat aggaagacta aggaaagtga gatgtagtgc
     4441 tatatttggc aaacaaccta taaaagaaca aatagctgaa ttaaagcaaa gggttcatat
     4501 tgttgtagct actccaggta gaataattga ccatataaat aaaggtacta ttaagttgga
     4561 ggatataaag tatttaataa tagatgaggc cgataaaatg tttaataaag gttttgttga
     4621 acaaatggaa aaaatattat taaatttacc taaagagaaa atagtaggtc ttttttcagc
     4681 tacaatagat gaagagataa aatatatatg tgaaaaatat ataccagatt acagtgttat
     4741 aaatatagag gaaaataaga gtgatactaa tcaaagaaca agacaaatag atgacaaaat
     4801 aatcaagacg aatgaaagag agaagtatat ccttttaaaa gaattaatat acagcgaaaa
     4861 tccaaagagt gtgataatat tttgtaatac taaagagaaa gtatctaaat tatataataa
     4921 gatgagtaaa gaaggttttt taataagaga gttacatgca gatttatcgc aagaaagaag
     4981 aatttttgtg attaaggatt ttaaaaaaca aaagtttaat gtattagtta gtagtgatgt
     5041 agcgtctaga ggaatacata ttgatgatat ttctttagta ataaattatg atgtgccaca
     5101 agataaagaa aactatatac atagaatagg tagaactggt aggaagagaa atagtggaaa
     5161 ggcaattact atagtaactg aaaaggatga aaaatatata gagaatatag aaacgtatat
     5221 aggatacaaa ataaatgaat taaaagatat agaaaaaagc agaattacgc atggcaaaat
     5281 tttatttgaa gaatattcaa aagaaatcct aaaagaagtg tcaaagagaa agaaagccga
     5341 taaaaattct tacaaaggta aagatataaa actaaataca gaaagtgaag ttgttaaatt
     5401 atatttaaat gctggtaaga agaagaaaat aagagtctta gatatcgttg gtgcatttag
     5461 taatataaaa ggtattacta atgatgatat aggtgtaatt gaagttcaag atttatgttc
     5521 atatgtagat atattaaatt ataagggaga tttaatatta aaaaaacata aggagatacc
     5581 tataaagaaa aaaatggtta aggtgaaaag agatatacga taatttagtt attactgctc
     5641 tttctgatga agaaatcgta ggtttaagta aaagtatcaa tgttgatgaa ttgctctgtt
     5701 atctaaatga agttgcaaaa aaacaataga agttgttaag taaaagaatg ttgattttac
     5761 ctatattcta ggctatacta tttttaagtg attatgctaa tagtcatttt aaatataagt
     5821 aataaatata tgtttataga aacataaaag gagggaaata tatggcatat tttaactata
     5881 ataacaaaca atgctactat aatgaaattg gagatggtac accattactt tttttacatg
     5941 gaaatacagc ctcttctaag atgtttaatg agataatcaa tttttataaa gatgaatata
     6001 aagtaatatt aattgatttt gtaggtcatg gaaaatctca aatggtcgat aagtttgccg
     6061 ctgacttatg gtttgatgag gctatgcaag tgatatgttt tttagaagtg atgaactata
     6121 aaaaagtaaa cataattggt agtagtggag gagctcttgt tgcattaaat gttgcacttg
     6181 aaagacctga tttagtgaat aaggtaattg cggatagttt tgaaggagaa gttcctctag
     6241 agtcatttgt acaaaatgtg aaaatagagc gtgaagcatc aaagcaagat gatggtgcaa
     6301 aagcttttta tatttataat caaggagaaa attgggaaag agttgtagat aatgatacag
     6361 aagctatttt tgaacattat aaaactatag gaaaattttt tcataaacct ctagaaacta
     6421 tgcaaccaga ggtgctttta acaggaagta gagaagatga ttttgtatct ttaatatcta
     6481 atgatttttt tgaaaatact ttttcatcac ttcttgaaaa gattaaaaat ggtaaaatgt
     6541 atttgtttga taaaggtggt catcctgcaa ttttatcgaa tggattagat ttttcaaatg
     6601 tagcaaagaa atttttagaa gaatgattta acccaaattt ataataatga aaactataaa
     6661 atagattgta aaacttacaa aagtaagtgt acatatactt tattcttatg atgaaataga
     6721 attgttaaaa caaaatattc taatagttaa gttattacat ttgtatattc aataggtgta
     6781 gaaagagata ttattggatt ataaagttgg gattaaataa taatatgaag ttttatttat
     6841 tcaagtattg tagcttaact atataaatct tagaataaat ttatatagtt aagttgtagg
     6901 attaaataat ttagttaaat aagtctatta tctcctcatc agatagactt tttaatacac
     6961 cttcattaga aagttctcca tttataaatt gatttataag ttctttttta ctttcttgta
     7021 attttattat cttttcttct atagttcctt tagcaatcaa ttttataact tgtactgaat
     7081 ttttttgacc aaatctatga gctctatcac tagcttgatt ttctactgat ggattccacc
     7141 atgggtcaaa gtgaattacc atgtcagcag atgtaagatt taaacccgtt ccacctgctt
     7201 ttaaagatat taaaaaaact tttttatcta tactgttatt gaactcatct acaagttcaa
     7261 gtctttcttt agcattagtt ttaccatcta tataatggta tttaatttta tacttatcaa
     7321 gttccttact tatgttctta agcacagagg taaattgtga gaacaacaat attttgtggt
     7381 tttcgtttat actatctcta agtatttcta aacatgtttc aatttttgaa cttttcttat
     7441 tgtaatcttt tactactata cttgggtcta aacaaagttg tcttagttta gttaaataag
     7501 aaaatataac tattttatct ttctttagat ttttatcttt tattttatct tgtatatcct
     7561 ttgaatatac actatatatc tttttctgct ctttattcaa ttcaacaaaa aagtttttct
     7621 caatcttatc tggaagttct ttcataactt gttttttact tcttctaaga ataaaaggtt
     7681 ttatcaattt tttcagattt ttaacattat cttctttatt tataaataat tcctgaaact
     7741 ttgctttact atatagatag ccaggcatta taaaatcaaa tatagaccat aattctagga
     7801 gattattttc cataggtgta ccagtgagtg caaatttatt ttctgcattt atacttttta
     7861 cagaagcagt tactaaagct aatggatttt ttatattttg agcttcatct aatatgcaat
     7921 aatcaaattt tatttcacta tatttttcta aatcatttct aagagtacca tatgttgtaa
     7981 gtattacatc aaaattttct aattccataa aacatttttc tctatctctt ttacttccat
     8041 gtatcaataa aacttttata tctggagcaa atttttcaaa ttcattcttc caattataaa
     8101 tgagtgatgt tggtgtaaca ataagacttt ttttattgga taatgataat aaaaatgcaa
     8161 tagtctgtat tgttttacca agacccattt catcagctaa tataccacca aatttataat
     8221 aatctaaaac tttaaaccag ttgagaccat ttatttgata gtcacgaaga tttgcattta
     8281 aatttgcggg aatttctaaa tttatactat caaagtttct aaatttttca catatactgt
     8341 ctagttcttt tttaccatct ataaacttca aatttttact acgtatcata tcatttatat
     8401 atagagcttt atttttatga attttattat tttttgatgt acccattata tctagatttt
     8461 caactaattc aaaaaaatct tttgtttctc tttctgataa atctataaag tttccatctt
     8521 taagtttata aaaagtgcgt ttttcttgaa aagcttttaa aatgtctttg tactcttttg
     8581 gatttatatc agatatatta aaattaaatt ctagataatt ctggttagtc tgattgattg
     8641 aagctttaat tgatgaagcg ttatatattt ttttcaattt aaacttatca gaataatata
     8701 tatctccaaa ttcctttaga gattctaatt gtaaatctaa aaatgtaaat aggtcgtggt
     8761 cagttccttt aaacacataa tgattatttt cttttgtaaa ttgtgaagaa gtcagtttat
     8821 tttcaatggt agtttctttt tgtatgttgg gaagtacaaa ttttttatct tcatcatcat
     8881 atatatactt tacatcacaa catatattgc tatcaatcat atcaaaatag aactcagatt
     8941 taaaatcttt tgttatatta ttttttatgt tatcatctaa atgaacttct tgagatatag
     9001 attttaatct aggaactagt aatcctaaaa catccttaga atcctcttta tcaaatttta
     9061 gctctttagt ctttgataat acttgatata tttttgaata atcatgagct tttttatggg
     9121 ataacaaata gatattgcca tcatataaaa gtacatcatt ttttttagta agtggaacag
     9181 gtagtgaatc tttagaacat aagactattt tatcttctat attttttaag tcaaacctta
     9241 taggtagagt atcatttaat atttttgggt gatattcttc tttagaaaaa ataagggtaa
     9301 aatctttgta cttaatagca tttaaaaatt gttttaaaga gcttgcattt atctccataa
     9361 atttttttga gtgtgatgaa gaaaaactgt atgaaagatt tgtcccatat tcttctataa
     9421 tatctactaa cttttcatct tcatcagcaa aataatgaat gttgggatca taagtaaatt
     9481 ttttcccaaa atctaattca tatccattaa gttttgaata tgcaaattca gtaatgtttt
     9541 ttaaaatgta cattttatca attcctattt taaattcagc aattgcttta tttgaatcca
     9601 tatttatcaa tacatctaaa ttaacccttt ctcttttagt attatctaac aaagaaagta
     9661 attgcttgct taaatctaag ctggttttag aatttgtact agagagctta tccttatctg
     9721 cacctaatat atctattaga ataggaggaa catctttttt attttttatt tgttttaagc
     9781 tttttatcac aatagcaact atatgtttac atataaaaat gtttttacca tttgattgac
     9841 agtcagcaca actgcaatca ttttcaatta tcttaaagtg ctttatatct atagttattg
     9901 agttaaaata aaagctataa ttatcttcag aattgactcc accacgaaat gtcagcagat
     9961 tattttgtag gtcatcaata tctatgtcta tataatcaac tagttgattg gtgtaatatt
    10021 ttacacctct tgcccatctt gatggttctg tatttcttct tattaattta tatatcatat
    10081 ctattttcat attattcacc ttacctcact gtatatatta taatctaaat gcattcaatt
    10141 tacactctaa atttaagact aaaattaggg cagatattga tagcttttat ctattgcaag
    10201 atatgtataa ataacaattt actattagat ttttgttgaa ttatcttata aactatgagt
    10261 gaaa
//
LOCUS       DAMKOJ010000106        10217 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000106 DAMKOJ010000000
VERSION     DAMKOJ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10217
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.115"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            55..1293
                     /locus_tag="PC592_003135"
     CDS             55..1293
                     /locus_tag="PC592_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF4057073.1"
                     /translation="MNNGFYKLNSAVLNFDIKSDVNKIRFNHYIMRKENIQRLQGTLP
                     RGQFYMTVRRAATDLQLSISTISRLVREFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKHMELDCVCNDEFVDNSDIELDCNSKDNSFNGDINVETEYCSNEYLFNNDVE
                     HNYDNFYNKDTIKNKSIFNISTIKKYINESFDTNKSENSNLQQESINFNFNDTCNAID
                     KRTNNSIKSNQNKKAMKLSDINVLSDKDITNKKNYFNHTHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNIHPCKEGNSNDSSNYIHSNYTTYDD
                     SVRERKKYENVRYWNPICEI"
     gene            1762..3063
                     /locus_tag="PC592_003136"
     CDS             1762..3063
                     /locus_tag="PC592_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4057074.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDKKSLAIKTSDVTNIITWGQNFGLDGHIKILKENLA
                     RRSINQTCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKVD
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            3139..3414
                     /locus_tag="PC592_003137"
     CDS             3139..3414
                     /locus_tag="PC592_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF4057075.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELIIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            4472..4702
                     /locus_tag="PC592_003138"
     CDS             4472..4702
                     /locus_tag="PC592_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4057076.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            4695..5276
                     /locus_tag="PC592_003139"
     CDS             4695..5276
                     /locus_tag="PC592_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4057077.1"
                     /translation="MNNKKHWYDYLWIFSSVYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMMLFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(5850..6527)
                     /locus_tag="PC592_003140"
     CDS             complement(5850..6527)
                     /locus_tag="PC592_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF4057078.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTIRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            7058..7579
                     /locus_tag="PC592_003141"
     CDS             7058..7579
                     /locus_tag="PC592_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF4057079.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKEVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQSL
                     ETWINSLKDNMGN"
     gene            7962..8759
                     /locus_tag="PC592_003142"
     CDS             7962..8759
                     /locus_tag="PC592_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4057080.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKRVVLIGQSAGGF
                     VAQSFIVKYPNMVEGIMMIGTCPYGIDYYSKLDIFWLKQTEWMLKLFPDRLLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGLIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            9139..10029
                     /locus_tag="PC592_003143"
     CDS             9139..10029
                     /locus_tag="PC592_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4057081.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKKAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDGCEKLLREECARYGILTD
                     MKEIIKAYKRSESYTQIKFF"
BASE COUNT         4038 a         1013 c         1843 g         3323 t
ORIGIN      
        1 taaaaatact tatctagtta ctagcaatta ttagtagaaa tgggggaaat agagatgaat
       61 aatggatttt acaaattaaa ttcagcagta ttgaactttg atattaagag tgatgttaac
      121 aagataagat ttaatcatta tataatgaga aaagaaaaca tacaaagact tcaaggaact
      181 ctaccaagag gacaatttta tatgacagtg agaagagctg ctacagattt acaactttct
      241 atttctacta taagtaggct tgtaagagag tttttggatt tggggataat aagattagtg
      301 tctaagggtg taaaaggtaa tcgttctgta tatagttatg taagtataga gtttaatgga
      361 agtttatttg atgatagcaa acatatggaa cttgattgtg tatgtaatga tgaatttgtt
      421 gataatagtg acatagagct tgattgcaat agtaaagata attcttttaa tggagatata
      481 aatgtagaaa ctgagtattg tagtaatgag tatttgttta ataatgatgt agagcataat
      541 tatgacaatt tctataacaa agatactata aagaataaat ccatttttaa tattagcact
      601 atcaaaaaat atatcaatga atcttttgat acaaataaat cagaaaattc taacttacaa
      661 caagaatcaa taaattttaa ctttaatgat acatgtaatg caatagataa aagaacgaat
      721 aatagtataa aaagtaatca aaataaaaag gctatgaaat tgagtgacat caatgtttta
      781 agtgataaag atattacaaa taaaaagaat tactttaatc atactcatgg catacaaaaa
      841 ggcactaaat ctgtaacaaa gaaaaaagaa tccttaaata aatttaataa aaaaaatata
      901 cagcaaagca ttataaatat gctaaataaa aaatcaggta agaattttaa aatcgattct
      961 ccaataagca taaaacttat caatgaaagg ctaaaggagg gctatgtctt agaagatttc
     1021 tacaaagtta ttgaggtaaa agtggctaag tggaaaaaca ccataatgga aatgtatata
     1081 agaccagaaa ccttgtttag ctataagttt gagtcctatg taaatgaaaa catatctatg
     1141 aaaagtcaaa gtaatattca cccgtgtaaa gaaggcaata gtaatgatag cagtaattat
     1201 atacattcta attatacaac gtatgatgac agtgtgcgcg agagaaaaaa atatgaaaat
     1261 gtaagatact ggaatcctat atgtgaaatt taattagtct aagaatgtat ttatgataaa
     1321 taagatgtta atagcgaata gtgagctact gcaaatgata tatcaataac tagtagtgaa
     1381 ttatattgaa tgatatatca ataattggta gtaagttata tcaaataaga tattactatc
     1441 gagtagtgaa ttatattgaa caatatatca ataattggta gtaagttata tcaaataaga
     1501 tattactatt gagtagtgaa ttatattgaa caatatatca ataattggta gtaaagtata
     1561 tcaaataaga tattgctatt atgtagtaaa ttatataaaa caatgtatca gaataaagag
     1621 tatattaata atttgtagta tatcatgacg aataatatag tcataacaaa tagtgtgtca
     1681 taacaaataa tgtatttata attgataata tatttaaaaa tcaaaatata aaaacttatg
     1741 aggaaagtga gattaattta tatgggtaaa tcaaaagatg ttgaaataga gaagtctatt
     1801 ttaggcacaa ttcttttaga caataaatta agctataagc tagatgaatt aaatgaaaac
     1861 atgtttatga atgatatatg tcttgagata tttaaaatta tgaaagaact taaaaaagaa
     1921 aacatagtga ttgatgtggc cactgtgaaa tcaaagatag ataaaaaatc tctagcaata
     1981 aaaacgagtg atgtgactaa tataattact tggggtcaga attttgggct tgatggtcat
     2041 attaaaattt taaaagaaaa tttagctaga agaagcataa atcaaacctg ccaaaacctt
     2101 ttacacagcc taaatcttgg agaaaatatc gatacttgta tttacaaatt tgaaagtaat
     2161 ataaaggaga ttttggacaa ggatacttat gaaaatgatg atgtaaatag tatagcaggg
     2221 aaggtgcttg attttttaga aaacaaaaaa gatattggat ttaaatttgg tataaaatta
     2281 cttgatacca ctataggagg tctttttaaa ggagagttaa ctacaatagc agctaaatca
     2341 ggggttggta agactgcttt ggcacttcaa ataatgttaa attcatttaa gcaaggaaaa
     2401 aagactttat ttataagtag agaaatgacc agtgagcaag tatttatgag aaatatatgc
     2461 agagtaactg gtgtaagtac aaggaatatg aaatctaaag aaatagatga aaatgactgg
     2521 aaacttattg taaatgcgat aggtgattta agcgaaaata acttaattta tatcaatgat
     2581 aaggtagata caattagtgc aattagaaag aggataaggc aggtaaaacc agatttattg
     2641 atagtggatt atgtgcaact ccttacatct cagaaaagca tggataaaag agaaagggag
     2701 gtagctactt tttcgaggga actcaaaaat atgactttag attttaatat acctgtaatt
     2761 caattaagtc agttaaatga tgaaatgaaa gattcaagac cttatggaga tagacctatg
     2821 agggatagta aagccatcta ccacgatagc aacaatgtgg tttatataca tcaattaaag
     2881 gggagtgatt atgaagaagc agtgagagat attggagaaa gtgaggaggc agttagagca
     2941 tcagaataca ggggaattaa gatggttgat ttaatagttg cgaagtgtag agatggacag
     3001 actaggcata agcatttttg ttactttggg gataagttac attttcaaga gctaaattat
     3061 taggtcaata aagtagtaat aacaagctta ttaaaagtcg ggaaatagca aatagattat
     3121 aaaatatgag gtgaaaatat gttggaatta acaaaaatta tagaattact tgaagaacac
     3181 aagatagaag taagtattcc aaaggagtta cataagtata gtttattgga ataccttgaa
     3241 ttgtgtcaac aaagtggggg aacatatttt tatattaaga cactggaagg ggctttaaaa
     3301 gaggctagaa atgagcttat tattaaattg tttaatggga agaattatat ggaattagcg
     3361 aggatgtttg aaatgagtgt tattaatgtc aggcatattg ttagaaaaaa atagatattt
     3421 ttggagaata caagtgtgat atacttctga aatagaagtt attataattg aaataaaatt
     3481 ttggttaata gattaaagtt gtgtataagt ttaagattat agaggagtat aagtgtgatt
     3541 aacagcatga ttttgtgaat aaaattgagg atatatatga gctaaatgtg tgattaataa
     3601 ggtaaggttg tgtataagat tatgagtatg taaaaggata gtctataatt aatagttcag
     3661 agttgtgtgt ttggttaaga ttatataaga atttaataga ttaaactata ctaataaggt
     3721 aaaatcgtgt gtttagttaa agcttattat aaaatcttga tacatgatta atgatgtaat
     3781 atgtgaataa agttaagatt ataataggtt taaattgtga ctaatagaat aaaattgtga
     3841 ataaagttaa gattgtaata ggtttaaatt gtgactaata gagtaagagt gtaaacagag
     3901 aaaaacttca atatgagctt aacttgtgat taatagagta gggtgtaaca aaagaaaaat
     3961 ttcaatatga gcttaacttg tgattaatag agtagggtgt aacaaaagaa aaatttcaat
     4021 atgggcttaa cttgtgatta atagagtaag gtgtaactaa agaaaaactt caatatgagc
     4081 ttaatctgtg attaatagag taaggtgtaa atagaaataa acttcaatat gagcttaact
     4141 tgtgaataat agaataagat tgtgaataaa gttatagttt tagatgggta ttaacctgtg
     4201 actaatagaa tatgattagg tgtaaaatta tagagttgta taagaaaata ttatagatat
     4261 attaaatatt agataataaa tatttatata gatacacaaa agaaaaggcg atatgaagtt
     4321 aaacttaatg acttcatatc gttttttatt tgaaattcct ctgtatttag agtgtgattt
     4381 ttaatattga ggttttatgt gattaagtca cagataaaaa gtaagtatcc tgatataatt
     4441 cttatagatt aataatattg gggaggttat tatgtctaat aaaaaaaaga agtatgcaaa
     4501 tattttagca aatgagtgcg ttgcttgtgg tagctgtata aaagcatgtc caagaagtgc
     4561 tatctcagtt ccatgtggca ttagtgcaaa aattaataga gatttatgtg ttggatgtgg
     4621 gatttgtgaa aagatatgcc cagcatctgt aattgagatt ataacaatat taaaagagga
     4681 agaaggtaag tgtcatgaat aataaaaaac attggtatga ctatttatgg attttttctt
     4741 cagtatattt gatattggga tttgtaaata ttattttcgc ttggattgga ctaatttgtt
     4801 tctttgttcc actagctatt tctattgtta agggaaataa agcttattgt aataagtatt
     4861 gtggaagagg gcaactgttt aatttgcttg gaaataaatt gaagctgtca agaaatagag
     4921 atattcctaa atttattaga agtaagtggt ttagatatgg gtttttgaca ttttttatgg
     4981 taatgtttgc caatatgctt ttttcaactt atttagtatt tgaaggaagt agaaatttta
     5041 aagaagtagt gactttgttg tggactataa aaatgccttg gcaatgggcg tatcatggaa
     5101 ctttagtttc tccatgggtg gtacagtttg catttggttt ttatagtgtt atgctcacat
     5161 caactgttct tggtttgatt actatgatgt tgtttaagcc tcgttcatgg tgtgtttatt
     5221 gccctatggg tactatgact cagatgatat gtaaggcaaa gagtaagtct gtatagaaag
     5281 aatttatgtg atatttaaga gtttgttcaa gtagagatga gtagtaggtt tgaatatatg
     5341 acaaatatat gagtataggg gcatagattt agtttgtgta aggtaaactg atttatgctt
     5401 cttttttatg tcttagatta ttggctaagt ggaaataatt aatttagata ttaagaatta
     5461 ttcagttatt tgaagaaaat ataataatta acattatatg aatggatatt cattacatat
     5521 aagccagtta atagcaagat ttatttaata tgaagtaggt caagtattta aactaaataa
     5581 gatcatgaca attaatataa gtatagatat aaaaagatta aaagttataa cttataaaag
     5641 gtattctata taaatagtat gggaaaaata gtcaaattaa cttattagaa acaaaaaata
     5701 tacataaaaa ataaatgtaa atatcaaata aggtactata tcaaaataga tataagtatc
     5761 ttttttatta ttgaaattat gaaaatatat ttgattttac acaaaaaaga gtgcctcatg
     5821 aactaaaaag ttcattttga gacacacttt tacagtgtca aagaacgaag tttatcctta
     5881 tccaatactt ttataccacc acgagataaa gacacaatac cttctctagc aaaatatttc
     5941 aacattctcg atacaacttc tctggcacta cccatatact tagcaatttg ttcatgagtc
     6001 atatttatag tgctactacc atttttagct atctcatcaa ttaaaaaaga tgccaaacgc
     6061 ttatcaaaac tcataaaaag aatttgttgc atagcccaca taacatcaga aaaacgttca
     6121 gtagctaatt tatatgaaaa taactctgca tgaatatttt ctgtagataa ttttgcaaaa
     6181 acagaggaac taatctgtat aatatcgcag tccgtttcag catctacata gacatcaaaa
     6241 gttattgttt ttagaataca ggaagctgat aaaatacata catctccatc atcaagtcgg
     6301 aacagtgtaa cctctcgacc ttcatctgaa agtatgtatg tgcgtattgt tccagacttt
     6361 ataatcaaaa taccaataca gtcactatca ccacaatgta cgggattccc ttttttgtaa
     6421 tgcgaggtgt ttgctgaaga aattaataat tctttttgta agtcagtaag tttatcccaa
     6481 aaaggcaagc tatgtgtaag tatatcaatt tcattttgtg aaatcatacc atatctcctt
     6541 tcttaaattg ttataatccc atgatacaag tgaatagata aattgacaag tagtttgtta
     6601 agaggattat ttagtcagat agtaatagta tgatttatgt agaaaaaata tgataatata
     6661 tattcttgct attaatgaaa aagtgatata tttttgatga tagtagatgt gtacaactat
     6721 tgcatacagt ttatttttaa aagattaagt tccttatgta accttataga cataaaacct
     6781 gcaattatcg tagctatcaa atcagcgatt ggttgtgcat ataagatacc atttatccca
     6841 taaaataatg gtaggtaatc ccatagataa caatgctttt gggattgggg cagaccctaa
     6901 taattcaatt cttttgttac tttctttcat attcaacact tcccttctat tgacattaag
     6961 tctaaattat aatactataa attatagtga atatggaaaa tagtactata atttatagta
     7021 tttgtcaata gtaagaaaac taaaggagat gatttttatg gctacaatag acttaattgt
     7081 attgggaata gtaaagcaac aacccaagag tgcttatgat attcaaaagg aagtggaata
     7141 caggaatata tcacgttggg ttaaaataag tacaccatca atttataaaa aagtaattca
     7201 attagaacaa aagggatata ttgaaagtaa aactgtgaag aatggaaaaa tgccagaaaa
     7261 agcagtttat tcattaactg aattaggtga gacacatttc ttagacttaa tgtttgatac
     7321 atctagtaaa ccaataaata ttcttttaga ttttaatgct gttatagtaa atttaaatag
     7381 ccttacacca gaaaaacaga aattatgtct caataatatt gaagagaatg ttcaagagtt
     7441 aaagaaaact attgaggaaa atataagtat aaagacagaa gtaccagaga cagcaaaagc
     7501 agtgttggag caacagttgg tactagcaca atcattggaa acatggataa attctttaaa
     7561 agataatatg gggaattaga attagagaag ctaacttaat aatcattaaa caaaaaccag
     7621 catatttaat aatgagatat tagaaaaaat gaaacaaatg atataaactg aaaagtatat
     7681 ttaaaataaa gctcacttaa ttgagggtga atgttaaact ttctaagtgt aaggaggcat
     7741 tattcaggaa tctactcgac tactgttatt gttaatggtg tagaatcagg taaccttaat
     7801 tctggattag gcatatgatt tgattttgaa ttaggtgtat aattttgtta ataagtagaa
     7861 aaattggaat ctgtagtcgt ggttgtaaat ttcactttat cattgattaa catagctgtt
     7921 gatagaatat ttcaaaaatt agaatttgga gagtgagcac tatggaagaa aaatacatct
     7981 tatctgaccg agggaaagta tattattgga taaaagaaag taatagtgtg tttgcaaaga
     8041 acttaatttt tttgccagga ctaacagcaa atcatcatct ttttgatttc caaatacagt
     8101 acttttcaaa aaatcataat gtattggtat gggacgctcc tgctcatgga aaatcaagac
     8161 cttacttaga tttctcatat tctaacttgg tagaagaatt gaaagtaatt ttagataaac
     8221 aaaatatgaa aagggttgta cttatagggc aatcggcagg gggatttgtg gcacagtcct
     8281 ttattgtaaa atatccaaat atggtagaag ggataatgat gattggaact tgtccatatg
     8341 gaattgacta ttatagtaag ttagatattt tctggttaaa acagactgaa tggatgttaa
     8401 agttgttccc agatagattg ttgcgaaaca taatatctaa gatgtgtgga gctacgtctg
     8461 aaggcagaag gagtatgctg aaaatgttag aaggatacga aaaaaaagaa ctgtgtcatc
     8521 tcatgtatct gggatttgct gggcttatac cagaaattca agacttaaat atacattgtc
     8581 cagtttgttt agtagttgga gataaagaca agactggtaa agtaagaaaa tataatgagc
     8641 agtggcacaa taagactgga tatccattgc acattataaa aaatgcttca cataatgtaa
     8701 atgtcgataa acctaatgaa ctaaatcaga ttatggatat atttattaag caattataat
     8761 atataaaaat tacataccca ttaggtaaat tatgtagtat atgtgtttat agatggttat
     8821 agaaataaat atgtaataaa ctacttaaca cttaaaaagt agacttgtct agtgcataat
     8881 acaaagcatg atatatattt ttaagcgaaa tacattaaaa gaagaactag tggagataaa
     8941 acagatatta gatattataa atgattaact taaaagtact ataagtgtag agaaagatga
     9001 ctcatacgtt attaagggat tgtaaatgat tagtttaaaa gtactatcgt ataggattct
     9061 gcatatttag accctagtaa agatagttaa agtagtttaa aaactaaaaa attatataaa
     9121 ggaattaggt ataagaaaat gattgagagt ataccagcaa aacaaatttt acaaaaagtg
     9181 aaatttgaca atacaagatg gtttggaatt gactataata tgaacctcta tcgtggttgt
     9241 tctcatggat gtatatattg tgatagccgt agcacaatat acaacataga gaattttgac
     9301 aaagttagat ataaagaaaa tgtgatagaa attttaagta aagaattgcg ttcaaaaaga
     9361 aaaaaggggg tagtaggcat tggagctatg tctgacacat ataatccttt tgaaaagcaa
     9421 ctttgtatta caaagaaagc actagattta atttcggaaa atcattttgg agtgtctatt
     9481 gatactaaaa gtagtttggt ggttagagat ataccgattt tgcagaagat taaaaaaaat
     9541 aactctgcta ttgtaaagtt gactataacc actgcaaatg atgaattatc aaagaaaata
     9601 gaaccttatg taaatccaag ttctgtacga tttgaggcag tgaaagaact taatgattct
     9661 ggaatttttt gtggcatatt attgactcct atgcttccat ttttaactga taataaagat
     9721 gaaatacgag caattgtaga aaaagcacac aaggctaatg caaaatttat ttattgcatg
     9781 tatggtgtaa caatgcgtag tggtcagaga gagttttttt atgagcattt aagagatata
     9841 tcaccaaaat tggtacttaa atatcagaaa acatatggtt taaactatgt atgtactgta
     9901 caaaataaag atggttgtga gaagttgtta agagaagaat gtgcacgtta tggtattttg
     9961 acggatatga aagagattat aaaagcgtac aagaggtcgg agtcatatac tcaaataaaa
    10021 tttttttaag ataagctttg gataagatat aatagtgatg attgatgtgt tgatactcta
    10081 ggtaattact agagctgaca ttataattga atattagtat tgatattcta ggtaattgtt
    10141 agtgatgata ttatagatga atattaatat tgatactcta ggtaattgct agagctaata
    10201 ttatagatga atattag
//
LOCUS       DAMKOJ010000107        10160 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000107 DAMKOJ010000000
VERSION     DAMKOJ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.116"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(105..422)
                     /locus_tag="PC592_003144"
     CDS             complement(105..422)
                     /locus_tag="PC592_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057082.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLELLYRYVTGLEYIAIGLFTRRLDITIITIILVSTITTALYYLIRKKY
                     ITI"
     gene            complement(800..1000)
                     /locus_tag="PC592_003145"
     CDS             complement(800..1000)
                     /locus_tag="PC592_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057083.1"
                     /translation="MCFKTYILKRVLNNKHLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEKNNVVWRNEKSTPQQENA"
     gene            complement(1019..1432)
                     /locus_tag="PC592_003146"
     CDS             complement(1019..1432)
                     /locus_tag="PC592_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057084.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLIIYCILKEKRFLISSFLLIAI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLIVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(1416..1649)
                     /locus_tag="PC592_003147"
     CDS             complement(1416..1649)
                     /locus_tag="PC592_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057085.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            1761..1928
                     /locus_tag="PC592_003148"
                     /pseudo
     CDS             1761..1928
                     /locus_tag="PC592_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984867.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            2514..3206
                     /locus_tag="PC592_003149"
     CDS             2514..3206
                     /locus_tag="PC592_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4057086.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIMGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            3402..5474
                     /locus_tag="PC592_003150"
     CDS             3402..5474
                     /locus_tag="PC592_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4057087.1"
                     /translation="MEKYRALKLVSLIIISISFPLTILLATIGLAEPKYNIQKTSTKS
                     GIFNISNDFYDSNIFDEGTVASLLSNFKISVDSQLTSEEKSKFQTKSKSIDLSSNDSE
                     YDKIMINKQASEEYLGYLKNIKVYVINTYTGVFYTNTSYDNLNDFKQETKNYCNIEII
                     NNVGKSSYIKTINGEKFELNNLSMELNGVDEAFEAYVSFPEEPTMEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLFIILYSRIKCEVLKRHNVFLLIYSKIPMEFNIILVS
                     ISIAILTIYALAVSYHIDVIVLVSLSLLIVSNNIFFINVQLSYLENKMYIFKTSIIVR
                     VILWLIRTVREVSNAIKKVSLARKVIVIVIISLALIMVISARSISMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVDLQGGKFYIEIDGDLFKANLEFQKYEEEV
                     TNMEKDGI"
     gene            complement(5667..5990)
                     /locus_tag="PC592_003151"
     CDS             complement(5667..5990)
                     /locus_tag="PC592_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDF4057088.1"
                     /translation="MNSNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLDLSIANPKIISFMIVLLVAYKFKSIGISIITGVVSIYL
                     FGIIM"
     gene            complement(5983..6684)
                     /locus_tag="PC592_003152"
     CDS             complement(5983..6684)
                     /locus_tag="PC592_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDF4057089.1"
                     /translation="MERTQQLRESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEDSYE"
     gene            complement(6962..8347)
                     /locus_tag="PC592_003153"
     CDS             complement(6962..8347)
                     /locus_tag="PC592_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF4057090.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIVKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTADSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGVQLIPIK
                     QEHNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYRESLSDALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPEGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESIEELKAGL
                     SILKRLLEEKK"
     gene            complement(8451..9689)
                     /locus_tag="PC592_003154"
     CDS             complement(8451..9689)
                     /locus_tag="PC592_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF4057091.1"
                     /translation="MELFIQVIKFNIYISPLILFFILFTKKISKYTFKFNYFICLLII
                     VRMLFISKINLNILNINNSTINIYKHNINNYIPYSQDIILDIFMYIWILGIILISFHY
                     LRTNLKFYNYVENFKKEILEIDITSILDEQVKELNINKKLKIYKVKGVYSPAIIGLTC
                     CEIIIPEKKYNNKELRFIFKHELIHYKRKDNLFKLLISIICIIHWFNPILYLLKKYFN
                     ELCELSCDEIVIDKCSISEIKEYAYIILDTIKYQKTLKYSSFVSQFLNKKNITLKKRL
                     NYMFNQDKKKINLGFKLLLTFIIIGSIFTINSNFKQNEDIEDTTGKINYNKNGETYGT
                     DIIDSNGNSIEPELIQAIGRGKKVGYVKKRDLYDCDNQPNTPEEAVLYTRKRNFNIFK
                     ITIPLYDKEGVKIIGRFEIN"
     gene            complement(9702..10079)
                     /locus_tag="PC592_003155"
     CDS             complement(9702..10079)
                     /locus_tag="PC592_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4057092.1"
                     /translation="MIILKKIPKSELLVMNFIWDKGIDKIPAREVANYMENSHGWTKG
                     TTGKVLSRLSDKGFLEFEKDGRNTIYTIKVKHEEYLKFETKDFLELIHKNSIHSFISS
                     LGCENEMSDDDIKELEQWLKKMK"
BASE COUNT         3865 a         1216 c         1343 g         3736 t
ORIGIN      
        1 gaaatgaaaa agcttttagt gaaatagaaa atttagtaaa atagattaga aggtagcaac
       61 cgtaactagt tgctaccttc tcttagtatt aattttatta gattttatat agttatatat
      121 ttctttctaa ttagataata taatgctgtt gttatagtag atactaatat tattgttatt
      181 attgtaatat ctaatcttct tgtaaataag cctattgcta tatactcaag acctgttaca
      241 tagcgataaa gtaattctag tttaacagtt tttttcttat ctatatttcc atatattgat
      301 tctaatttat tgaaatattt tttactacaa aaagcagttt taggtttaat taaatatatt
      361 attgtagttc ctattataac tattattcca ataagtataa gattgatatt tccaaaatcc
      421 atagtagaaa cctcctgtta gatttgattt tcttaatcaa agtatatcag taacacaagt
      481 ataaagagta tctaaaatat tacaaatatt aacaggacgc ataaaactat atagtataag
      541 ttgcaataat aaaactaacg aaaattatca tactaaaaca taagacacgt tataatcatg
      601 ttagagaaat tcttgaatat acactaaaag tactctttct ataggagtgc ttcttttttt
      661 aaatttatta atgtataaac tatcaagact gttactcaaa accctttaaa attgatttaa
      721 atagctcttt ttaacaacat aatttatatg atataataaa aaatagaagt gtattcgcag
      781 tacacttcta tagttgtaat taagcattct cttgctgggg agtgcttttt tcatttctcc
      841 aaacaacatt atttttttca tctgtaatta ttaaatcaat ctcattatct ttcaaaatct
      901 ctgttgcagt acaaatgaga ttatctaagt cgaaacttcg agttatctct agatgtttgt
      961 tgtttagaac tcttttaagt atataagttt taaaacacat ttgtatcacc tcttgtattt
     1021 actctttttt ctctaaaaat atattgataa gtaaatatgc aacaaataaa aaaatctcaa
     1081 tgacacatag tgttatagct ataactataa gtgattgatt tttccatgca ctataagcta
     1141 tgatgaaaag aaatgtaaaa gtaaataatg tataattcat aattttaact aagatatgac
     1201 ttgttttcat tgttaagtac aagtctcttt catctgtact atcgtgtaat tcttcaacaa
     1261 taccttttct tgaaaaagca ttacaaaaat taaagattgc tattgcaatt aaaagaaatg
     1321 atgaaattag gaatcttttc tcttttaaaa tgcaataaat aattaaacta gcacaacata
     1381 acatacaaac tataataccc actataaaac ttcgtttact ctttactttc atgtttttta
     1441 tcctccattt ctttattttc ctttaaacaa catagttctt caatagttgt accaaacact
     1501 tgtgccatac gataggcaag cataagagaa gggctatatt gctctttttc aatagaaata
     1561 attgttctgt ttgatacatg gactaaatca gcgagttgtt gctgtgttag acccatattt
     1621 gttcgaaatt ctcgtacttt tgttttcatt ccataacctc tttctgtatg aagttaactt
     1681 catgtgaagt tagcttcata atatcctaaa atgagtaaaa tgtcaatctt attagataag
     1741 tattataaaa acctaaaaga aaaaaatatc taaggtttga aacgaaagaa tttttgaaga
     1801 acatacataa aaattcaatt tcaagtttaa tgtcagcgtt acatggtgaa tacgacgaag
     1861 tggatgaaga taaattaatt gaaatcgaag aacattttaa gagtttgaaa gaagaaaatg
     1921 acagctagat acataataaa taaaatgaag gtatgaaatt ataacttttt ctaccttcat
     1981 tttgtttatt attctgaaca tgttaagaaa atgaaataga tttgttttat atttatataa
     2041 attttaatag aatatgcata gtatatagta gatagtatgt ataaaaatag aatttaaata
     2101 agcagctatt attgcagcga aataaatgtt tctaagtata tttgggtgga agaaaattag
     2161 tgaaatgtaa ttcttccacc actcttccac ccaaaaaata aaaactgttc aataagaatt
     2221 aatatacatt aattcagctg aatccaatca aaatacttaa ataaaagtaa tctgaaaaca
     2281 acataattca aatcaattta ttcaaataaa cctcaatttc tcttaaatct taagaaatat
     2341 ttaagaatta ggataatatt ttcttaagat ttatatttta ttatagactt ataagagaaa
     2401 gttacaaaaa tgtaagtcaa agtaatataa caatttagtc attgttgaga aaggaagtga
     2461 aagatattgt ataatataga taagtattat tatacaatag aggaagtgaa aacatgtaca
     2521 atatattagt agtagacgat gataaagaaa ttgttgattc aatagaaata tatcttaaat
     2581 cagaaggatt taagatatat aaagcatatg atggaatgaa agctttggaa ataataacag
     2641 agaatgacat tcatctaata ctgatggata taatgatgcc taaattagat ggaataaaag
     2701 caactgtaaa aatacgagaa gaaagaaaca ttccaataat tttaatttca gcaaaaagtg
     2761 aagatacaga taaaataatg ggattaaata ttggagctga tgattatata acaaagccat
     2821 ttaatctatt agagcttata gctagagtta aatcaaactt aagacgatat gtaactttag
     2881 gtaattatga agatacatgt aaagaaattt taaaaagtgg agctttggag ttaaatacac
     2941 taacaaaaga agttaaaatt gatggtgaaa acataaaaat gactccaatt gagtataaaa
     3001 taattgaact tcttttagaa aataaaggac gagttttctc aatagatgag atatacgaaa
     3061 aagtatggaa tgaggaaagt tttaactcag aaaatacagt agcagtacat atcagacgaa
     3121 taagagaaaa gattgaaata aatccaaaag aaccaagatt tttaaaggtg gtgtggggag
     3181 ttggttataa gattgaaaaa ttttagtgga aaaattataa aagaaaagag tttaatattt
     3241 aattgcattt tgattttagt catttttaca tttacacaaa tgttaggaat tttaatatgt
     3301 tttaattttt tctctgagag tttaatttac tctatgggga ttatgctttt cttaaacttt
     3361 attttatata aaatactgac aatgtagatg aggtgaacaa cttggaaaaa tatagagcat
     3421 taaagttagt ttcattaatc ataatatcta tctcatttcc attgactata ttgttggcaa
     3481 caataggact tgctgagcct aaatacaata tacaaaaaac ttctacaaag agtgggattt
     3541 ttaatatatc taatgatttt tatgatagta atatatttga tgaaggaaca gtggcaagct
     3601 tattatccaa ttttaagata tctgtggata gtcagttaac tagtgaagaa aaaagtaaat
     3661 tccaaacaaa aagtaaaagt atagatttaa gtagtaatga ttctgagtat gataaaataa
     3721 tgataaataa acaagcttct gaagaatatt taggttatct aaaaaatata aaagtgtatg
     3781 ttattaatac atatacagga gtattttata caaatacatc atatgataat ttaaatgatt
     3841 ttaaacaaga aactaagaac tattgcaata tagagataat aaataatgta ggaaagagct
     3901 cgtatattaa aacaataaat ggagaaaaat ttgaactgaa taatctgagt atggaactaa
     3961 atggagtaga tgaagctttt gaggcatatg tatcttttcc agaagaacca actatggaag
     4021 atggaatagt atacactaat tttcaaatat ttaaacaagc tacagaaaaa gtaagattat
     4081 tttttgtagc tagtttaagt ttagcaatta tatgtttatt atttataatt ttatatagta
     4141 gaataaaatg cgaagtttta aaaagacata acgtattttt actaatatac agtaagatac
     4201 ctatggaatt taatataata ctagtatcta tttcaattgc aattttaact atatatgctc
     4261 ttgctgtatc ttatcatatt gatgtaattg tgttagtttc tttatcttta ctgatagtat
     4321 caaataatat attttttata aatgttcaac tgagttattt agaaaataaa atgtatatat
     4381 ttaagacaag tattatagta agagtgattt tatggttaat aagaactgta agggaggtca
     4441 gtaacgctat aaagaaagta tctttagcaa gaaaagttat tgttatagtg ataatatctt
     4501 tagctttaat catggtaatt agtgctcgaa gtataagtat gggattactg ttttctatat
     4561 gtattttttt aggatttaca atatatataa ctaaaagact ttcatatctt agttacgtaa
     4621 tagaaggtac agaaagaata aaaaagggag aattagatta taagataaaa attactggga
     4681 atgataattt tacgtcttta gctgaaaata taaataatat tggagaaggt cttgatagag
     4741 ctatagaaga gcaagtaaaa agtgaaagaa tgaagtctga ccttataaca aatgtatctc
     4801 atgatttgaa aactccactt acttctataa taaattatgt agatttaatt aaaaaagaag
     4861 aatcaataca accagagtat ataaatgatt atataaatgt gcttgagtca aagtcaaaaa
     4921 gactaaaatt attgatagaa gatttatttg aagcgagtag agtaagtagt ggcaatatag
     4981 aattacaaat tagcaagatt gatttagtgc aactattaag acaaagtata ggtgaacttg
     5041 aagaaaaatt atctaaaaat aatttatatt taaaattaaa tgttccaaac gataaggtgt
     5101 atatatgggc agatggaaga agaatgtaca gagtatttga aaatctttta tctaatatag
     5161 caaaatattc tttagaagaa actagagtct atattgatgt atatgactat ggtgaaaatg
     5221 taaaggtaac tatgaaaaat atatcttctt atgaattaaa ttttgaccct agtgagatta
     5281 tggaaagatt taaaagggct gatgaatcaa gaaatactga aggtagtgga ttaggacttg
     5341 ctattgcaag agacttagta gatttacaag gtggaaaatt ctatatagaa atagacggag
     5401 atttatttaa agcaaattta gagtttcaaa aatatgaaga agaagtaact aatatggaaa
     5461 aagatggtat ttaagtatac atacttttga ttgtaggaag ctcttattat aatatattag
     5521 aatatttata gtagaggatg aagagtaaaa acagagtaga tttaagccac tctgtttttt
     5581 tatttaaaat caataatata acaatttaga ttaaaattgt acatatgttt ataaaataac
     5641 ttataaaata aaacattatc taaatgttac attataattc caaataaata tatagatacc
     5701 actcctgtaa taatagaaat accaatagat ttaaacttat atgcgacaag aagtacaatc
     5761 ataaaagata taattttagg gttagctata gataaatcta ggctatctcc attaaaaaat
     5821 acatctttag cagttaatga agtaagtatt gctacaggta taaatttcat gatttttttc
     5881 aaaaaatcag gcatctcttt ttttgagaaa attaacatag gaagcactct tggtagatat
     5941 gtaacaatgt acattccaat tataataaaa aatatataat tactattcat aagagtcctc
     6001 ctttttacag taagattctt ctataaagaa accaattaaa gatgctaaaa ttgatgcaac
     6061 tattattact aaattgcttt tgaataatgc atataagata accgaaataa tgattgatga
     6121 tataaatacc acaatataaa tcttattttt tatttgagaa actattaaag ctataaacat
     6181 agaagtcaat ataaagccag aaatagaact gtctatagat atactttctc ctaaaaatgc
     6241 tccaataaaa ttagctaaaa ctgatgaaat taagcagaag aaattgagat aaatagcatt
     6301 tctatcagac caatttccag cagtaaattt ttcataatta actgcaaaag tttcgtctgt
     6361 tatagtatga caaaatggca atataaattt tggactttta ttttttatgt acatgttcaa
     6421 attagaactc attagaaaat gtcttaagtt aactataaat gtagtcaaaa caatagatgt
     6481 tacacttgca ccagtagaaa tcattgaagc tgcaatgaat tgagagcttc ctccaaatac
     6541 taaagttacc attagtgcta tttgaaaagg tgaaagacca gatttttgta atagtattcc
     6601 tcctactata cctataggta tataacctaa gaatatagga attgaagcaa taaagctttc
     6661 tcttaactgc tgagttcttt ccacaataaa tcactccttt tgtattaaat gtattaaagt
     6721 atttgtaaaa cataaaaata gattaatttt ataattgcaa ttataattaa aaataaattt
     6781 gaattaatat ataaattact gtataacaaa tagacagtct taaactatta ttaaatttta
     6841 tctatttgtt actattatgt aacaatacat attaatctct ataaattaat tactatctgt
     6901 tgtaatttta ttttaacaac aaaaaaaaat acacacaatt aaaatattgt gtgcaataca
     6961 attatttttt ttcttctaat agtcttttta atatgctcag accagcttta agctcttcta
     7021 tactttctgt agcacataca gctattctta ttgcagaaat tggtttttct tttccaacag
     7081 caaaacgttc agaagcataa acctgtacac cttctttaag tgcttgtatt tcaaattttt
     7141 ctgccattat tccctcagga agaatcaacc atctaaatat acattcttca tttcccaaaa
     7201 gattataccc agataaatat tgattaataa tcttgtttct tcttcttgca gatttacgac
     7261 gtgcattaat taatttatca gcttcacctg atgtaatcat acgataagca atttctgtta
     7321 aaaaataaga ttgagataaa ttaatgttgt ataatgcgtc tgataatgat tctcgatact
     7381 gtttaggtgt agagatatat gctagccgta aactaggtgc aataattttt gataaactcg
     7441 taatataaat tgtttggtta ggaagatagg aagctactgg atttaaatgt gtttcattaa
     7501 gtaaactatg aatagcatcc tcaataacaa ttaaattgta tttagatgca atatttgcaa
     7561 tcatttttcg tccattttgt gacattatat gtgtagttgg attttgataa tctggtatta
     7621 tgtatagacc tttaatattt tcatttttac aagcatacaa tagtccttct tcactaattt
     7681 cattatgttc ttgcttaatt ggaattagtt gtactccaag cattttagct gctgtcttta
     7741 ttcctggata agttaatggg tctacaccta ttctatctcc atgttgaaat aaacctgcca
     7801 aaatagcaac aattgcattt tgtccaccac ttgcaggaag taagctatct gctgtagttt
     7861 caagcccagc tttataaatt aatttggcaa tagcttcttt ttgccattta gcgccatctc
     7921 tttgtccata ttggaatata gttttaaaat cgatttcttt aactatgtgt ttaaataaag
     7981 tattcatttc ttctagtgta aaatctgggt tcattgtacc catttcaata aatgtaattt
     8041 tattattact ggacattaag aataggtttg aacgtgtatc ataagataca aaagttccac
     8101 ttcctgtaac tccacttatg agaccttttt tttcacaaat tttaaaagct ctagagatag
     8161 tactcacatt tacatctagg aaatctgcca attcacgttg gggtggcaat ttagtacctg
     8221 gcaataaaaa cccattgttg atatcttgtt ctagttgttc tgcaagggcc ttatataata
     8281 tctgaccttt tgaaggtctc tttggcttcc agttcatagg ataattttca aaagaattaa
     8341 ttggcataag ttttcacctc acgttattag tttaattttt ttctttatct aaaacaataa
     8401 attctaagga tacaaataaa aactgatagg taataattct atcagttctt ttaattgatt
     8461 tcaaatcttc ctataatttt tacaccttct ttgtcgtaaa gaggaattgt tattttaaat
     8521 atattaaaat ttctttttct tgtgtataaa acagcttctt ctggtgtatt tggttgatta
     8581 tcacaatcgt acaaatctct tttttttaca tagcctactt ttttacctct acctattgct
     8641 tgtataagtt ctggttcaat tgaatttcca tttgagtcta ttatatcagt accataggtt
     8701 tctccatttt tattataatt aattttacca gtagtatctt ctatatcttc gttttgttta
     8761 aaattagagt taatagtaaa tattgaccct attattataa aggttaacaa aagcttaaaa
     8821 cctaaattaa ttttcttttt atcttggtta aacatataat tcaacctctt ttttaaagta
     8881 atattttttt tatttagaaa ttgagataca aatgatgaat acttcaaagt tttttgatac
     8941 tttattgtat ctaatattat atatgcatac tctttaattt cactaatgct acatttgtca
     9001 atcacaattt catcacaaga taattcacat agttcattaa agtatttttt taataagtat
     9061 aaaattggat tgaaccaatg tattatacat attatactaa ttagaagttt aaataagtta
     9121 tcttttcttt tataatgaat taattcatgt ttaaagataa atcttaactc tttattattg
     9181 tacttttttt ctggaattat tatttcacag caggttaaac ctataatggc aggggaataa
     9241 acacctttaa ccttatatat tttgagtttt ttatttatat ttagttcttt tacttgttca
     9301 tctaagatac tagtaatatc tatttctaaa atttcttttt taaaattttc tacgtaattg
     9361 taaaatttaa ggtttgttct taaatagtga aaagagatta atataattcc taatatccag
     9421 atgtacataa atatatctaa aataatatcc tgactatatg gtatataatt attgatatta
     9481 tgtttataga tattaatagt gctattattg atatttaata tgtttaaatt tatttttgat
     9541 ataaatagca ttctgactat tattaaaaga catataaaat aattaaactt aaaagtatat
     9601 ttgcttatct ttttagtaaa taaaatgaaa aaaagaatta gtggacttat gtaaatatta
     9661 aatttaataa cctgtataaa taattccata aaatatgtct cctatttcat tttttttagc
     9721 cattgttcaa gttcttttat gtcatcatct gacatttcat tttcacaacc taatgatgat
     9781 ataaagctgt gaatagaatt tttatgtata agctctaaaa aatccttcgt ttcaaatttt
     9841 aaatattcct catgtttaac tttaatagta tatatagtat ttctaccatc tttttcaaat
     9901 tctaaaaaac ctttatcact taatctagaa agtactttac cagtagtgcc ttttgtccat
     9961 ccatgagaat tttccatgta attagcaact tctctagctg gtattttatc tatgccttta
    10021 tcccatatga aattcataac taacaactca gatttgggta tttttttcaa tataatcact
    10081 ccctttaact tgattatatt agacaaatgt ctaacagtca atataatata tcatcattta
    10141 taaagaatat ctatattatt
//
LOCUS       DAMKOJ010000108        10143 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000108 DAMKOJ010000000
VERSION     DAMKOJ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10143
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.117"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            171..866
                     /gene="cas6"
                     /locus_tag="PC592_003156"
     CDS             171..866
                     /gene="cas6"
                     /locus_tag="PC592_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF4057093.1"
                     /translation="MIKCLEMSVKVYLLENISLDNTSKEIRKLIDDTLIIEEKYKEFH
                     NKAGFKNYSFNLLYPLEKDKVYKKDCIYTFIIRTVDSELGMYFMNNLKNQYSDKIKVI
                     TMSKKVIPKKHIESIYSVTPIIAKFEDGYWRSNKTVEDLEKRIRENLIKKYNEFTNSK
                     IDEDFELFQVIKFINRKPISTKYKNISLLGDKISFKVSENDMAQEIANFALGVGVGEI
                     NSRGFGFVNYRWL"
     gene            857..2617
                     /locus_tag="PC592_003157"
     CDS             857..2617
                     /locus_tag="PC592_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cse4"
                     /protein_id="HDF4057094.1"
                     /translation="MVIGGENLLKDCLEIFEKEYKSLGNRLITDSYVLSYGTYILVKN
                     FSNIDILEVSKNNVDSTEDIYHKFCELDYLSKLVSIDKSVDSKKIIHSNNYLSFFVKK
                     ENLRPDKNNNVKLTEEIIDNYYDALLNPRIKYKSDKRKKEIYDSIENKYGKVDENKLN
                     KIRLWIKTNIFDLVESVKKDKNYLKIFFDEKIELYNDENQKYLYPNIYNKNDFNVIID
                     GKNYGLPNDNMQLNEKKPFLKLKTRIRNSTPYLISDDEVLLQKAFFDYLMNKAANGEE
                     VVYISSEKGIHRKTDIPNEFSGYILRIKKGKELEIHDFDTVVNLNTKIKRINVECIIP
                     IEYERHNLKPNLEIGYINNLIKLEKTIDTIFFNKFMCNSYFKEIKNINLSDLVLRDIL
                     IRHREGLYTWFYKGRDNIVKQTFSNYSMGIIENSIKNNNYIRAKEQYNLRIAIINYFH
                     GGSNMADKIKVISESLFEKINSIKTKCIQSDEEYYFAVGQLASYFISKNKSKNKNHSL
                     INPILNAQNRKKIMLEIEKLFKKYNYDISYDNNRRFKNLYSMIVGYEVEEKKVNRDLL
                     IGGYLYYSLIYTKSEENENE"
     gene            2604..3599
                     /locus_tag="PC592_003158"
     CDS             2604..3599
                     /locus_tag="PC592_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I CRISPR-associated protein Cas7"
                     /protein_id="HDF4057095.1"
                     /translation="MKMNRRVYGVLGIKSIMSNWNADFSGYPKTTSTGEVFGSDKALK
                     FPMKKMWENEGEKVLYVKSLKIDESKKGEIKIRPKSLKERYEELFDIEELKLEKNQQK
                     VLENLFKAIDVKNFGATFAEEGNNIGIMGAVQIGQGFNKYEDINVEEQQILSPFRDPR
                     AKDKKKSTNEEEKEDANSTTLGKKIVSDEAHYFYPFSINPKAYEVFVNMGVTDGYTKN
                     DYKKFKEAALVSATAFNTNSKLGCENEFALFVETDEELYLPDLAQYITFEKREKSKDL
                     ICINIIHLIAELKDDIKSVEIYYNPYKIEIKPFKDEILPKIDKVKFMNIFTRKEV"
     gene            3601..4341
                     /gene="cas5b"
                     /locus_tag="PC592_003159"
     CDS             3601..4341
                     /gene="cas5b"
                     /locus_tag="PC592_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF4057096.1"
                     /translation="MEVLKFNLSGKTAFFKKPDVNSIIYFTYGNIHKIALMGILGACL
                     GLGGYNQQSKEDEYPEFYSLLKDIKMSIVPKHEFGYINKKVHIFNNSVGYASKEEGGN
                     LIIKEQWLENVSWDIYIQLEDSTTSRELKRRFLSNKFVYIPYLGKNDHIANISEIEII
                     TDFYKTEDINRVDSFFIREDFEFEKSYFDDNDDYEEPFKYQEKLPYRLHRMTNQYILE
                     TIIFTNMSVKLINKKEVYQVKGLNLIFI"
     gene            4365..6923
                     /locus_tag="PC592_003160"
     CDS             4365..6923
                     /locus_tag="PC592_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF4057097.1"
                     /translation="MYFKKVELFDISNNINNCKNIYAHINKDRKPETLKEHSDLSYSY
                     LMKLCVKKDLSSCLERIENKFFKKDSFLSKNFYREIILNMVYMHDIGKINSSFQFVKM
                     QNKNFKKISLRYTKHSFISSMLYFDYYFEKLKKYDFEEKKILSLFLMINTYTISKHHG
                     VLKSFKEFLFLFKDEFINIKENFKDLFKNNYNLELKSVPKTIEKMVRGVEGYLDDSHI
                     KDNLAIDLYIYSKLMFSIVTSCDFYATSEYNSGNSIDGFGTIDNYNKYYDVLKKSEIY
                     KGMKKYREYLNNNSECPYKENDINRLRTEMSIEAEDAITHNTRKRIFYLEAPTGSGKT
                     VTSINLALKSIELNQSLKKIFYIFPFNTLVEQTKDVFINEIFNSVKDIQKDVVVINSI
                     TPIQTEDKEEDNKNVEYCVTKQEIDYDKSLLNRQFLHYPIVLTTNIGFFNYLFGVSRE
                     ECFPLIHMINSVIILDEIQNYKNEIWKEIILFLEKYADILNIKFIIMSATLPRLNKLG
                     CNDDNFAYLVKNREKFFKNHLFKDRVNISFEMLNSEINDIEEISEKVIEEAEIYNKIL
                     IEFIKKSSALEFYKNIKEKLKYKLEDVFLLTGDDNKLERKKIINKIKDMNSVILVATQ
                     VVEAGVDIDMDLGFKDISTIDSDEQFLGRINRSCKKLNSKVYFFNLDDASKIYKKDVR
                     KERHLTLNEESNRKIILDKDFEKYYDKIIARIEENKHKHNDKNIEVFIKDIVGNLNFT
                     EVKKWMALIPDLKEYTIFLNTIVKDESGNMIVGSDVWYEYISLLKNDNVEYSEKRVKM
                     SEIMEKLDYFTYKVQKFDNSFNDLVGDIFYIDDGSKYFTEGKFDRSKFNQNEFL"
     repeat_region   7113..7802
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7113..7142
                     /rpt_unit_seq="gttaaacagtaacatgagatgtatttaaat"
     gene            7887..8381
                     /locus_tag="PC592_003161"
     CDS             7887..8381
                     /locus_tag="PC592_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HDF4057098.1"
                     /translation="MKITGTLINYYFHCKRQCWLLGNRINLEENSEDVKIGRLLHELK
                     EEKSKYKEIAIENIKIDKLTREYLVEVKKSDADIEAVKWQVLLYLKKLKEKGIVRKGK
                     IEFIEKNKTNKKIVFVDLSEVSEEQLISIEREIVNLINSDKAPCPDLKKGCKKCAYYE
                     YCYI"
     gene            8416..9414
                     /gene="cas1b"
                     /locus_tag="PC592_003162"
     CDS             8416..9414
                     /gene="cas1b"
                     /locus_tag="PC592_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF4057099.1"
                     /translation="MGKTKYITSMGELTRKDNSICFRKNGRNVYIPVENTSEIFCLNE
                     VSLNSKLLDFLSRANIVVHFFNYYGGYSGTFYPKEYLISGKVTVAQVKTFEDRREEIA
                     KSIVNGIRINAINTLSHYYKHGNSEIQPLLSHLKKDSINKLEKSNNIKEILSVEGDIW
                     QTFYTSFKYILREEFIFNKRVKRPPDNPLNAMISFGNSILYSKTVTAIYNTHLNQSVS
                     FLHEPSESRFSLSLDLSENFKHVITFKTIFDLVNNRKINIEKHFDKNLNYCVLNDEGK
                     QIFINSLEERLESVKEHPKLKRKVSLKTCIKLDAYKMLKCIMEEKSFIPYNIKDGL"
     gene            9625..9915
                     /gene="cas2"
                     /locus_tag="PC592_003163"
     CDS             9625..9915
                     /gene="cas2"
                     /locus_tag="PC592_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF4057100.1"
                     /translation="MKKKNNLNYNYVFVVYDVGEKRVSKVFKVCKKYLSHFQKSVFRG
                     EITPSKIMSLKRDLENIIDKDNDFVCIIKLMNSNTFEEEILGNNSNCENMIL"
BASE COUNT         4404 a          813 c         1550 g         3376 t
ORIGIN      
        1 tttttttgaa actttgtgat tttatttgtc gaataaaaaa taaaaaaatt taaaggaaaa
       61 agttaaaaaa taaagaattt tataactata aattatattt tagagtttat tgttattaaa
      121 tagatgaaaa aatcctaatg tggattatca gaaaatgagg aggttgttaa ttgataaaat
      181 gtcttgaaat gtctgtaaaa gtgtatcttc ttgaaaatat ttctttagat aatacatcaa
      241 aagaaatacg taaattaata gatgatacat taattataga agaaaaatat aaggaatttc
      301 ataataaagc tggatttaag aattattctt ttaatttatt atatccatta gaaaaagata
      361 aggtttataa gaaggattgt atatatactt ttattattag aactgtagat agtgaattag
      421 gaatgtattt tatgaataat ttaaaaaatc agtattctga taaaataaag gttattacaa
      481 tgagtaaaaa agtgatccct aaaaaacata tagaaagtat ttactctgtc actccaataa
      541 tagctaaatt tgaggatggg tattggagaa gtaataaaac agtagaagat ttagaaaaaa
      601 gaatcagaga aaatttaata aaaaaatata atgaatttac taacagtaaa atagatgaag
      661 attttgaatt atttcaagtt attaaattta taaataggaa acctatttct actaaatata
      721 agaatatatc tttacttggt gataaaataa gttttaaagt atcagaaaat gatatggctc
      781 aggaaattgc aaattttgca cttggagttg gagtcggaga aattaattct cgtggatttg
      841 gttttgtaaa ctatagatgg ttataggagg tgaaaacttg ttaaaggatt gtttagagat
      901 ttttgaaaaa gaatacaaat ctttaggaaa tagattgata actgatagct atgtcctatc
      961 ctatggaaca tatatattgg tgaaaaattt ttcgaatata gatatattag aagtttctaa
     1021 aaataatgtg gatagtacag aagatatata ccataaattt tgtgaactgg attatttatc
     1081 aaaactggtg tctatagata aatcagttga ttccaaaaaa ataatacata gtaataatta
     1141 tctttcattt tttgtaaaaa aggaaaactt aagacctgat aaaaataata atgtaaaact
     1201 tacagaagaa attattgata attattatga tgctttgtta aacccaagaa ttaaatataa
     1261 gtctgataaa agaaaaaaag aaatctatga ttcaatagaa aataaatatg gtaaagtgga
     1321 tgaaaataaa ttaaataaaa taagactatg gataaaaaca aatatatttg atttagttga
     1381 atctgttaaa aaagataaaa attatttaaa aatatttttt gatgaaaaaa tagaattata
     1441 caatgatgaa aaccaaaaat atttatatcc aaatatatat aataaaaatg atttcaatgt
     1501 aattattgat ggtaaaaact atgggttacc aaacgataat atgcaattaa atgaaaaaaa
     1561 gccatttttg aaattaaaaa caaggattag aaattcaact ccttatttga ttagtgatga
     1621 tgaagttttg ttacagaaag ctttttttga ttatctaatg aataaagcag cgaatggaga
     1681 agaagtagta tatataagta gcgaaaaggg aattcataga aaaactgata taccaaatga
     1741 atttagtggt tatatactga gaataaaaaa gggtaaagaa ttagaaatac atgattttga
     1801 tactgtggta aatttaaaca ctaaaataaa aagaataaat gtagaatgta taataccaat
     1861 agaatatgaa agacataatt taaaaccaaa tttagagata ggatatatta ataatcttat
     1921 aaaattggaa aaaacgattg atactatatt ctttaataaa tttatgtgca atagttattt
     1981 taaagaaatt aaaaatataa acttaagtga tttagttcta agggatatac ttattagaca
     2041 tagagaaggt ttatatacct ggttttataa agggagagat aatatagtaa agcaaacttt
     2101 ttcaaactat tctatgggta taattgaaaa ttctataaaa aacaataact acataagagc
     2161 aaaggagcaa tataatttaa gaatagctat aataaattat tttcatggag gaagtaatat
     2221 ggcagataaa ataaaagtta ttagtgaatc tttatttgaa aaaataaatt ctataaaaac
     2281 gaaatgtata caaagtgatg aagaatatta ttttgcagtt gggcaattag catcatattt
     2341 tatatctaaa aataagtcaa aaaataaaaa ccattctctg attaatccta tactaaatgc
     2401 acaaaataga aaaaaaatca tgttagagat agaaaaatta tttaaaaaat ataattatga
     2461 tataagttat gacaacaata ggcgatttaa gaatctatat tctatgattg taggatatga
     2521 ggtagaagaa aaaaaagtta atagagattt attaattggt ggatatctat attacagttt
     2581 aatatacaca aaaagtgagg agaatgaaaa tgaatagaag agtatatgga gtattaggta
     2641 taaaatctat aatgtcaaac tggaatgctg atttttctgg atatccaaag acgacatcaa
     2701 caggagaagt ttttgggagt gataaagcac ttaagtttcc catgaaaaaa atgtgggaaa
     2761 atgaaggtga aaaagtttta tatgttaaat cattaaaaat agatgaatct aagaaaggag
     2821 aaataaaaat tagaccaaaa tcattaaaag agagatatga agaattgttt gatatagagg
     2881 aactaaaact agaaaagaat caacaaaaag tactggaaaa tctatttaag gctattgatg
     2941 ttaaaaattt tggtgcaaca tttgcagaag aaggaaataa tataggaatt atgggcgcag
     3001 tacaaattgg acaaggattt aataagtatg aagatattaa tgttgaagaa caacaaatat
     3061 tatccccatt tagggatcca agagcaaaag ataagaaaaa gtcaacaaat gaagaagaaa
     3121 aagaagatgc aaattcaact acattaggaa aaaaaatagt aagtgatgag gctcattact
     3181 tttatccatt ttcaataaat ccaaaagctt atgaagtttt tgttaatatg ggtgtgactg
     3241 atggatatac taaaaatgat tataaaaaat ttaaagaagc tgctttagta agtgcaactg
     3301 cattcaatac aaattcaaag cttggttgcg aaaatgaatt tgcattattt gttgaaactg
     3361 atgaagagtt atacctacca gatctggcac aatatataac ttttgaaaag agagaaaaat
     3421 caaaagattt aatttgtata aatataattc atcttatagc agaattaaaa gatgatataa
     3481 agagcgttga gatatattat aacccatata aaatagaaat aaagcctttt aaagatgaaa
     3541 tattacctaa gatagataaa gttaaattta tgaacatatt tacaagaaaa gaggtataat
     3601 atggaggttt tgaaatttaa cttaagtgga aaaactgctt tttttaaaaa accagatgta
     3661 aatagcataa tttattttac gtatggaaac atacataaaa ttgcacttat gggtatttta
     3721 ggagcttgtt taggacttgg tggatataat caacagagta aggaggatga gtatccagaa
     3781 ttctactctt tacttaagga tataaaaatg tcaatagttc caaagcatga atttggatat
     3841 ataaataaaa aagtccatat atttaataat tctgtaggat atgcatcaaa agaagaaggt
     3901 ggaaatttaa taataaaaga acagtggctt gaaaatgtta gttgggatat atatatacaa
     3961 ttagaagatt caactacaag tagagagctt aaaagaagat ttttatctaa taaatttgta
     4021 tatatacctt acttaggcaa aaatgatcat atagctaata taagtgaaat agagataatt
     4081 actgattttt acaaaacaga agatattaac agagtagaca gtttctttat aagagaggat
     4141 tttgagtttg aaaaatctta ttttgatgat aatgatgatt atgaagagcc atttaaatat
     4201 caggaaaaac ttccttatag actgcaccga atgactaatc aatatatttt ggaaactatc
     4261 atatttacta atatgtcagt taaattgatt aataaaaaag aggtatatca agtaaagggt
     4321 ttaaatttaa tctttattta aatttatagg tttaggagaa ttatatgtac tttaaaaaag
     4381 ttgagttgtt tgatataagt aataatataa ataattgcaa aaatatttat gctcatataa
     4441 ataaagacag gaagccagaa actttaaaag aacattcaga cttatcatac tcatatctta
     4501 tgaaattatg tgtaaaaaaa gatttaagct cttgcctaga gagaatagag aataaatttt
     4561 ttaaaaaaga ttctttttta agtaagaatt tttatagaga gattatcttg aatatggttt
     4621 atatgcatga tataggtaag attaattctt catttcagtt tgtaaaaatg caaaataaaa
     4681 attttaaaaa aatttcactt agatatacta aacattcttt tatctcttca atgctatatt
     4741 ttgattacta ttttgaaaag cttaaaaaat atgattttga agaaaaaaaa atattgagtt
     4801 tatttttgat gataaataca tatacaatat caaaacatca tggggttctg aagtcattta
     4861 aagaattttt atttttattt aaagatgagt ttataaacat taaagaaaat tttaaagatt
     4921 tatttaaaaa caattataat ttagagctta aatcagttcc caaaactata gaaaaaatgg
     4981 taagaggtgt agaagggtat ttagatgata gccatataaa ggataactta gctatagact
     5041 tatatatata ttcaaaattg atgttttcaa ttgttacatc ttgtgatttt tatgctacat
     5101 cagaatataa tagtggtaat tctatagatg gttttgggac aattgataat tataataagt
     5161 attatgatgt attaaaaaaa tctgaaatat ataaggggat gaaaaaatat agggaatact
     5221 taaataacaa tagtgaatgc ccatataaag agaatgatat aaacagattg agaacagaaa
     5281 tgagtataga agctgaagat gcaattacac ataatacgag aaaaagaata ttttatttag
     5341 aagcaccaac tggaagtgga aaaactgtta catctataaa tctagcactg aaatctatag
     5401 agttaaatca atctttaaaa aagatatttt atatatttcc atttaacaca ttagtagagc
     5461 aaacaaaaga tgtatttata aatgaaatat ttaattctgt taaagacata caaaaagatg
     5521 ttgtagttat aaattcaata acaccaatac aaacagaaga taaagaagaa gataataaaa
     5581 atgttgaata ttgtgttact aaacaagaaa ttgactatga taaatcattg ttaaatagac
     5641 aatttttaca ctatcctata gtacttacaa ctaatatagg tttttttaac tatttgtttg
     5701 gtgtatcaag agaagaatgt tttccattga tacatatgat aaatagtgta attatattag
     5761 atgaaataca aaattataaa aatgagatat ggaaagaaat tattttgttt ttagaaaaat
     5821 atgcagatat attaaatata aaatttatta taatgtctgc aactttacct agattaaata
     5881 aattaggatg taatgatgat aattttgcat atctagtaaa aaacagagaa aaatttttta
     5941 aaaatcacct ttttaaagat agagtaaaca taagttttga gatgttaaat tcagaaatta
     6001 atgatattga agaaatatca gaaaaggtta tagaagaagc agaaatatat aataagatac
     6061 tgatagagtt tataaagaaa tcatcagcac tagaatttta taaaaatatt aaagaaaaat
     6121 tgaagtataa gttagaagat gtttttttat taacaggtga tgataataaa ttagaaagaa
     6181 aaaaaataat aaataaaatt aaagatatga actctgtaat tttggttgct acacaagttg
     6241 tagaggctgg agtagatata gatatggatt tgggatttaa agatatatct acaattgatt
     6301 ctgatgaaca atttttggga agaataaata gatcttgtaa aaaattaaat tcaaaagtat
     6361 acttttttaa tttagatgat gcaagtaaga tatataagaa agatgttaga aaagagagac
     6421 atttaactct taatgaggaa agtaatagaa aaattatttt agataaagac tttgaaaagt
     6481 attatgataa aataatagcc agaatagaag aaaataagca taaacataat gacaagaata
     6541 tagaggtttt tataaaagat attgtgggaa atttgaattt tacagaggta aaaaaatgga
     6601 tggctttaat accagattta aaagagtata caatcttttt aaatactata gttaaagatg
     6661 aatctggaaa tatgattgta ggaagtgatg tatggtatga atatatatca ctactaaaaa
     6721 atgataatgt tgagtattct gaaaagaggg tgaaaatgtc tgaaattatg gaaaaactag
     6781 attattttac gtataaagtt cagaaatttg ataattcatt taatgattta gttggagata
     6841 ttttttatat tgatgatgga agtaagtatt ttacagaggg aaagtttgat agaagtaaat
     6901 ttaatcaaaa tgaatttcta taatgtattt agattatata gagaatattt atcccaagtt
     6961 aattaattag aattagttta aagctattga aatatagata ttttatatct tatatatatt
     7021 ttctaggatt agctgggata aaaaatctgt atattagtgt tttcagtgta tttaagggaa
     7081 ttatattttt aagaagtact gattttaaag tggttaaaca gtaacatgag atgtatttaa
     7141 atatgtttaa gtcagatggc tcaccaaatc aaatgtttgt taaacagtaa catgagatgt
     7201 atttaaattt tattgtagct gttataactt ctttatttgt attagttaaa cagtaacatg
     7261 agatgtattt aaattgattt attagaggaa aatagagaat taaatattaa gttaaacagt
     7321 aacatgagat gtatttaaat tattgctcta aatttagtag accaagttca atttctgtta
     7381 aacagtaaca tgagatgtat ttaaatttaa atgctttata aagtattaat tcattttgta
     7441 acgttaaaca gtaacatgag atgtatttaa attattaatc cttctattgg aaaatatcgt
     7501 cttcaagagt taaacagtaa catgagatgt atttaaatta tagttttgta gctctttcaa
     7561 gttcatctgc atttgttaaa cagtaacatg agatgtattt aaatgctaac ttaattactt
     7621 gttccacatt tgctaatacc gttaaacagt aacatgagat gtatttaaat aaatattcaa
     7681 tatagttttt aaatacactt tccattgtta aacagtaaca tgagatgtat ttaaattcat
     7741 tagtacttgt tattccagta aaagctactt tggttaaaca gtaacataag atgtatctaa
     7801 attactctat cataaaattt taatatatta aacaaactaa tatgtgatat acttatgtat
     7861 aaataacaaa ataaataggt gatgttatga aaattacagg aactttgata aattactatt
     7921 tccattgtaa aagacaatgc tggttgcttg gtaatagaat aaatttggaa gaaaatagtg
     7981 aagatgtaaa aataggtaga cttcttcatg aactaaaaga agaaaaatca aaatataaag
     8041 aaattgcaat tgaaaatata aaaatagaca aattaacaag agaatattta gtagaggtta
     8101 aaaagtctga tgctgatata gaagctgtta agtggcaagt tcttttatat ttaaaaaagt
     8161 taaaagaaaa gggaattgta agaaaaggga aaattgaatt tatagaaaaa aataaaacta
     8221 ataaaaaaat agtctttgta gatttgagtg aagtatctga agaacagctt atatctatag
     8281 aaagagaaat tgttaattta ataaatagtg ataaagcacc atgtcctgat ttaaaaaaag
     8341 gatgtaaaaa atgtgcctat tatgaatatt gttatatata aagaggtata agaaacatat
     8401 aaggaggtgt taatattggg aaagacaaaa tatattacct caatgggtga actcacaaga
     8461 aaagataatt ctatatgttt tagaaaaaat ggaaggaatg tatatatacc agtagaaaat
     8521 actagtgaaa tattctgtct aaatgaggta tctttaaatt caaaattact ggatttttta
     8581 tcaagagcaa atattgttgt tcattttttt aattactatg gtggatatag tggaactttt
     8641 tatcctaaag aatatttaat aagtggaaaa gtaacagtag cacaggtaaa aacctttgaa
     8701 gatagaagag aagaaatagc aaaatccata gtcaatggta taaggattaa tgcaataaat
     8761 acattatcgc attactataa gcatggaaat tcagaaatac aaccattatt atcacatcta
     8821 aaaaaagatt ctataaacaa gttagaaaaa tcaaataata taaaagaaat attatcagtt
     8881 gaaggagata tttggcaaac attttatact tcctttaagt atattttaag agaggaattt
     8941 atttttaata aaagagttaa gagaccacca gataatccct taaacgcaat gatatcattt
     9001 ggtaacagta ttttatattc taaaactgta actgctatat ataatacaca tctaaatcaa
     9061 agtgtaagtt ttttacatga accaagtgaa agtagatttt ctttaagtct agatttaagt
     9121 gaaaatttta aacatgttat aacttttaaa actatatttg atttagttaa taatagaaaa
     9181 ataaatattg aaaaacattt tgataaaaat ttgaactact gtgttctaaa tgatgaagga
     9241 aagcaaattt ttataaattc tttagaagaa agattagaat cagtcaaaga acatccaaaa
     9301 ttaaaacgaa aagtaagttt aaaaacctgt ataaaattag atgcttacaa aatgttaaag
     9361 tgtataatgg aagaaaaaag ttttattcca tataacataa aagacggatt ataatttaaa
     9421 cataaagtaa gtattttaat atagaacttt gatatatata agaatgataa ttatgctatt
     9481 ataagtatac ataatatatt attgaaataa tataagtttt tagaagtatt tcaagatgag
     9541 aaaggagaaa atactgaaaa ataattattc tattataatt tgccaaggtt ttgtctattt
     9601 ttcagtttaa atagtatatt acatatgaaa aagaaaaaca atttaaatta taattatgta
     9661 tttgtagtct atgatgtagg agaaaaaaga gtaagtaaag tttttaaagt gtgtaaaaaa
     9721 tatctctcgc attttcaaaa atcagttttt agaggtgaaa taactccatc taagattatg
     9781 agcttaaaac gtgatttaga aaatattata gataaagata atgattttgt atgtataata
     9841 aagttgatga attctaatac atttgaagaa gagatattag ggaataatag taattgtgaa
     9901 aatatgatat tataaatcta attactatat ttgtaaaaaa taatagctta ttaaagagta
     9961 gtaaaattgg gatataattt atgatagaga ctgcaagtag atttttgtaa aaaggattta
    10021 cttgcagtat ttttgttatg tataactgtt aacattagtg tacaaaacat tatcaatagc
    10081 atttttctat aatgaagaaa tactattata atgggaaaat tttattaata ctaggtaata
    10141 ata
//
LOCUS       DAMKOJ010000109         9802 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000109 DAMKOJ010000000
VERSION     DAMKOJ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9802
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.118"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            112..837
                     /locus_tag="PC592_003164"
     CDS             112..837
                     /locus_tag="PC592_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF4057101.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNTGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGANFRFCDLS
                     NSDIRGANLENSNLEYATLNGVISDKSTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAKDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            complement(1047..2243)
                     /locus_tag="PC592_003165"
     CDS             complement(1047..2243)
                     /locus_tag="PC592_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057102.1"
                     /translation="MLKTNNLSVGYNNKVVVSDINIEVKSGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINHISRKALSKKMALVLTNRLLADLMTVQDIVNIGRYP
                     YTGFFGNLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKNLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDENIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFESISDESFDLAIRNLNASKIIIDT
                     GFSVGETNKRNIDIVKEALKLDKKVYSFRNRDESKKYYDSLDNKIEHVDKVSQIVDSI
                     NMNNLL"
     gene            complement(2246..3271)
                     /locus_tag="PC592_003166"
     CDS             complement(2246..3271)
                     /locus_tag="PC592_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF4057103.1"
                     /translation="MDFINKMRIRNTTIFIVLIISIILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGSCLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVRNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILITVGVLGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIKFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQVS
                     KLIFKTSDNRILIPVVIFLGSIVTALCDLISRVVLSPVELPISTITSLLGAPIVVMLL
                     MKRKDRA"
     gene            complement(3343..4473)
                     /locus_tag="PC592_003167"
     CDS             complement(3343..4473)
                     /locus_tag="PC592_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4057104.1"
                     /translation="MKLKSNVLKQFFLIILAIVMVGGLIGCSKNDKENKQVSNGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDIA
                     TSELNKTVQKIEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     regulatory      complement(4703..4884)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(4937..5830)
                     /locus_tag="PC592_003168"
     CDS             complement(4937..5830)
                     /locus_tag="PC592_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDF4057105.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDREGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVDKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKAEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMDKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     gene            complement(5910..6812)
                     /locus_tag="PC592_003169"
     CDS             complement(5910..6812)
                     /locus_tag="PC592_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF4057106.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNISSEDIIKLKTIINESTFYNYDVFKRERCTIHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDNSFEDPQKTVYFTKRVIKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSSVPFPIK
                     LKVCSRVNGEERQSSNTRLFISDVSDIVSELSKGMTLESGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            complement(6862..8022)
                     /locus_tag="PC592_003170"
     CDS             complement(6862..8022)
                     /locus_tag="PC592_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF4057107.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQINKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            complement(8177..8482)
                     /locus_tag="PC592_003171"
     CDS             complement(8177..8482)
                     /locus_tag="PC592_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF4057108.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTIKTITALDDI
                     TIYHKLAIKDIAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            complement(8580..9554)
                     /locus_tag="PC592_003172"
     CDS             complement(8580..9554)
                     /locus_tag="PC592_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF4057109.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
BASE COUNT         3176 a         1795 c         1086 g         3745 t
ORIGIN      
        1 aagatgatat tttatatatt atttagaagt tttttactta ttgttatata attaaatata
       61 tgactatttt gctactacat atataaaaat aaatttgtga aggtgatttt aatgaaaact
      121 atttctaaac aagaattaga aaaaacactt gagaaacatt atttatggct taaaaacaat
      181 aatactggag aaaaggcaga tttaaaagaa ttaagattgg aaaacatgga tttaagagga
      241 tactgcttaa gtaatattga cttttcgtgg tctgacctta tcaatttaaa tttagaaaaa
      301 gcagatttag aaaactctat ttttaataat tcttatcttt cggattgttc attaaaaaat
      361 tctatattaa aaaatgcaga cttaagtggt gcaaatttta gattttgtga cttatctaat
      421 tcagatatta gaggagctaa tttagaaaat tctaatttag aatatgctac tttaaatgga
      481 gtaatatcag ataaaagtac tcgttttttt aaattgtact gtcctgaaac aggagcattt
      541 ataggctata aaaaatgttt taattttaga atggtacaat tattaatacc tagcgacgca
      601 aaaagagtat ctgctacatc aaatgcttgt agatgtgata aggcaaaagt actatcaatt
      661 actagtatag atggtaaaga atcttttaaa agcgctcgtg catatgctga tgaaaatttt
      721 atatatagag taggagaaac gattgtagct aaagatttta atgaaaatag atggaaagaa
      781 tcaaccacag ggattcactt ttttttaact agagaggaag ctattggtta tctgtaaagt
      841 aacttatttt tataacgaca catataaaat acataaatga taaaaaaagg tctgtctcaa
      901 aatagagata agcctttttt cattgttgaa ataatgaaaa tatatttaat ttcatacaaa
      961 aagagtgcct catgaactaa aaagtccatt ttgagccact catcttttta tattttgtaa
     1021 tttactggta tatttgattt taaaggttat agtaaattat tcatattaat actatctacg
     1081 atttgagaaa ctttatctac atgttctatc ttgttatcca agctgtcata atacttctta
     1141 ctctcatctc tatttctaaa agaataaact tttttatcca attttaaagc ctcttttaca
     1201 atgtctatat tcctcttgtt tgtttctcct acactaaatc ctgtatctat tataatctta
     1261 gaagcattta aatttctaat agccaaatcg aaactctcat cacttatcga ctcaaatgga
     1321 ttttctgtaa acatttttat ccccatagtt ctaccaattt cataatcaat atcattttca
     1381 tgtattattc cagaatatag acctatacct ttcttagtaa aagctctata aattggtgtc
     1441 gctttacctc caccaccaat tataaaaact tcatttttag atttattact aatttctact
     1501 gaacccaaaa gactattaaa atttttatca tctaattcat aaagtgaatt tataatattc
     1561 tcatcaacta catcttcagg ctgaccataa gctatgactt tattattttt tataagagca
     1621 accttatcac aactttttaa tgctatgtct atttcatgca atgaaagtat tactgatatt
     1681 gacttttctt tacttaaatt tttcagtata tttatgagtt ctaatctatg ttttatatcc
     1741 aagtgagttg taggctcatc caatatgatt atttctggtt cttgaacgag agctcttgca
     1801 accaatacct tttgtttttc tccatcactt agttcatcaa aatatctttt ctttaaatgt
     1861 aaggcatcta cagactccaa tgcttcatct accattatta aatctttctt agataaatta
     1921 ccaaaaaatc ctgtatatgg ataccttcct atattgacta tatcttgtac agtcattaaa
     1981 tcagctaata atctatttgt aagtactaaa gccatttttt ttgataatgc ttttcttgat
     2041 atatgattta tgtttacacc gttcaaatat atctcacctt ttattggtga tataagctta
     2101 gataaggacc tcaatagagt agtttttcca gctccattac ttcccaaaag acatagtatt
     2161 tctccacttt ttacttctat atttatatca cttactacta ccttattatt gtatcctaca
     2221 cttaaattat tagttttcaa catgtctaag ccctatcctt ccttttcatc aatagcatca
     2281 ctacaattgg agctcctaat aaagacgtta tcgtacttat tggtaattct actggcgata
     2341 aaactactct tgatattaaa tcacaaagag ctgtaactat actccctaaa aatattacta
     2401 ctggtatcaa aattctatta tctgatgttt taaatatcaa ttttgaaact tgtggcactg
     2461 caagtccaat aaatcctata ggccctgcaa atgctgatac tattgctgcc aatatgctag
     2521 atataaatac tattaaaact ctaaaaaatt ttatatttat accaatactt tttgcatact
     2581 cttctcctaa taagaaagca tttaaaggtt ttattatgaa tacagtcatc aaaagaccta
     2641 acacaccaac tgttataagt atttctacct tttcccatgt aaatccagaa aaacttccca
     2701 tagaccacat agtaaattcc tttaatttat cactatttgc aaatgattgc aacacatttg
     2761 ttataccact acacacatat ccagtcataa ttcctattat taaaagagtt gttatatttc
     2821 ttaccttatt tgcaaataga atgactatag acattacaat taaagctcct ataaatgctg
     2881 ctacaaatat actcattgaa tttacactct caaagcccaa tgtgtatcct cccaaaatca
     2941 tgagtgctac tgataaagta gagcctgaag atacccctaa tatatatggt tcaactattg
     3001 ggtttttgaa aaatatttgt aataaaatac ccgatactgc taaacatgac ccacctacca
     3061 tggttgcaag tactctaggg attcttatat tgtatattat tttataatgt tctgtattat
     3121 ccattcccct taatacaaca tctattactt ctttaaattc aatttttaca gaaccaaatg
     3181 ctacacacac taaaaaagta agtataatac ttataattag cactataaat attgtagtat
     3241 tccttattct cattttatta ataaaatcca tttgtatact cctcttagca aagctatatt
     3301 aactaaaatc tataaaacca atcttttttt gtcctttctg tactatttat cataatttat
     3361 ataatgtttg attttttcac ctgtagtacc tgggtgaaac atctcaacta aatctactat
     3421 taattcgtcc gtcttatcta ctgattgata ataatctgga gcaaacaccc ataagtttcc
     3481 attttttaca acatccaaat cagccaatac aggtgcacta gattttatag aatctaagtt
     3541 tggtgcataa tctgaacttg atgagtatac aaatatatct gcatcctttg caacttcatg
     3601 caattgttca atactcactc gtccttcatt tgaatctatt gaagcacatg catttattcc
     3661 accagccatt tttatcatat tatccacata tgaatcctta ggcgctatat aagcacttcc
     3721 ttcatataca gatgcccata caactttagg tttagctttg ttttttattt ttttacttac
     3781 ttcttctatc ttttgtacag ttttatttag ttcactagta gctatatctt ctttatcata
     3841 aaatgcagct attaaacttg tccactccat tcttccaaat ggattttgct ctttatactc
     3901 attgtctaca acataattaa gacctaattc ttttaatttg tcaataaatt ttgtatcagc
     3961 ctctgataag ccactactca ctatagttaa gtcaggattt aaatctacta ttttttcata
     4021 atctggtgct aaatttgaac caacataatg tattttccca tctttcatta aatctttaat
     4081 ttctttaata gtccaatact gctcttctgt tgttactgct tttatactat ctagttcatc
     4141 tattgttctc agagaacaag cctgtgttgt ggatgctatt aatacattat ccacaggcgt
     4201 tctaactata ttagcgtttt tatatttttc aggaatttta attttctttg gtattaaaat
     4261 cagttctcga ttgtctccat cagttacttt tttaattcca tcttctaaat cttcaacact
     4321 aaatccacta gcatatttta attctaattt cttaccatta ctaacttgtt tattttcttt
     4381 gtcattttta ctacatccta taagacctcc taccataaca attgccagaa taattaaaaa
     4441 gaactgcttt aaaacatttg atttaagttt catctctttc actccaatat cttatttttt
     4501 atgagtggct aaaaaactat aataagatat gctttttaaa gtatatctta ttatagtttt
     4561 cctaaagtca tctttaataa gtataacctt ttaataaaat aaaaaacttc tcctagttta
     4621 ataaggagaa gttcatatat caactttaca aaaaatgaat tgatacttca ttttattata
     4681 aattacaatc tccaccctaa attgaactta tataatactg ggcaggtctc ctgactcacg
     4741 gcttttcctc catcaccctt cccaaaattt ttataagttt cagtggattt tgatttcgta
     4801 tccgtataca gtagcggggg ctgtagtaaa ttttcatcac tttccctatt aaactaatat
     4861 agtaccctag tattatttta atttaatttt tattaagata attgtaattt attgttgacc
     4921 tctttgcaag gtcgatttaa catatattta attcattcat caatttttta atttcacata
     4981 cttgtttttc atttggtttt acaaacggag cagtcatata atcgcttatt tgtagccctc
     5041 taatattcat ggcttttttc attgctggta taaatggatt ggttattaag taaaaatcca
     5101 ttgctttgtt aatatatttt tgaatttcta taaccttatc catatctcta ttattgtaag
     5161 cttcagccca tttggaacaa acttctggaa ttagatttga tagtccccct atacaaccag
     5221 ctcctccaga cattagatta tgtataaagt tttcatcata accactataa accttaaatt
     5281 ctgggaactc tgctttcata gtatttatta aatctctggt atgtcccatc aaagttactg
     5341 tatccttata tccaactatg tttttatgtt ttcttgcaag tcttaatgta agttctgggc
     5401 ttaaatcata accagttcta tctggataat tgtataaata tatttcagct tctgtattct
     5461 tagctatttc gctataaaat aactcaatgc tatcatcatc aagagagaaa taataagggc
     5521 ttattatcat aactccatct gctccactat tatgtgcata gtttgaaagt tctatagatt
     5581 catttataca catacgactt gtacctataa atacttttac tcttttatct acatgactag
     5641 ttactaaatc tataagttct ttttgcatat ccatagacat attaaagaac tctccagtac
     5701 ttcccattat gactagtcca tctacacctc catctataag atggtcgtac acttttttat
     5761 taccttctct atctaaattt ccttcttcat caaatattgt aacaactggt gtcaaaaatt
     5821 ctgctttcat aatttaaact cctaaaattt attttaatat gttcattaat acatcagatt
     5881 tagctttaat attaattata ttaaaacatt tacttaatgt aattttttaa aattccaata
     5941 ctctcaatct cacattcaac cacatctcca ctactcatat atcgaggagg tgaaaatccc
     6001 atccctactc cagaaggtgt tccagtagct ataatgtctc cagactctaa agtcatacct
     6061 tttgaaagtt ctgaaactat atctgaaacg tctgatatga ataatcttgt attagaactt
     6121 tgtctttcct caccatttac cctactacat actttaagtt ttataggaaa aggaactgaa
     6181 cttttatgta aaatacatgg acctaaagag gtaaatgtat ctaatccttt tcctctaaac
     6241 cattgaacat gttctttttg caactttcta gcagaaatat catttataac agtgtaacca
     6301 aagatataat cttctacctc ttcttttcta atattaacac ctgttttacc tattactact
     6361 ccaagttcaa cttcatagtc tagttgatta tttatctcaa aatgaccatc tatctcatct
     6421 tctggaccta ttgcctttat cacacgtttt gtaaaataaa ctgttttttg tggatcttca
     6481 aaactattat caaagtgagt ttgtgtttct tcaagatggt ctttatagtt cactcccaca
     6541 cataaaatat catgtattgg tttttctata ggaacatgta tagtacatct ctctctttta
     6601 aaaacatcat aattatagaa tgtactttca tttataatag ttttcaactt aataatatct
     6661 tcactagata tattttgaat taattcattt aaatctttaa agtttctact aagatttaaa
     6721 gaattaacat ctataataaa taattcatct ttagaaaaaa ctccagttct tttacattca
     6781 ttttcccctt cagtaaaact gacaaacttc ataatctcac cctttatcaa aattctatgt
     6841 atttagtttc ttacttaaag attatacata gttacatact ctagctattg ccatttcagt
     6901 atatccaaga gattctgctt ttgattgttt tccatttgct acatctacaa ccatatttag
     6961 caaatcatct gttagttctt ccattgtttg tggaccgtat ataactggac tagcatcaaa
     7021 atccatatta tcttccatat ttgcaaaggt tattttattt ccagttattt ttattactgg
     7081 agctattgga tttcctgatg gtgttcctct tcctgtacta aacaccacta tttgtgctcc
     7141 tcctgctacc ataccagcaa cagatgaagc atcatttcca ggtgtatcca ttataacaag
     7201 acctttctta ttaatttgtt tagcataatc atatacttca cttatttgtc tatgaccacc
     7261 tttatgtata cagccaagtg atttttcttc caaacttgtt aaaccaccag ctatatttcc
     7321 aggagatgga ttaccttctc taacttcttc tcctaccaat tttaatgaat tttcatatct
     7381 atgtactata tgtaatattt tttcttttac ttcctcattt actgctcttc tagctaatat
     7441 atgctctgca cctataaatt cagtagtttc acttaaaatt gatgttgctc ctaaatcaac
     7501 aagtttatca cttaattcac ctatcaacgg atttgctgct aatccacttg ttgggtcaga
     7561 cccaccgcat tcagttccta gtataagttc agatattgga aattcttctt ttctaagcaa
     7621 agaagcttct tgtgccattt ctctagcata acgaacagcc ttttctatag tttttaaagt
     7681 tccatgttct tcttgtatta caagagtttt tattggctta tttgttctct cttttattgc
     7741 atcaactacc aaatcatttt ggcaattttc gcatcccaaa gatacaacta ttacaccata
     7801 tacatttgga tttgctgcat aaccagccat aacatccata gttaattgtt ggtctgaatg
     7861 tacttgtgaa catccattct gattattaaa ggtaactgcc ccttgaactt gtgatgctat
     7921 tattctagtt gtatctgatg cacacacact agtaggcaat attaatatgt ggtttcttat
     7981 accaactctt ccatctggtc ttttatatcc ataaaatttc atactgattt cctcctaaaa
     8041 tagtctatat actttttata attttcatat attataattt ttattacact caataatcaa
     8101 acaattaaaa tcctatttaa caaccattca acaccaaaag caatgaatac aacttttata
     8161 aatccataaa tattatttat atattagtca taacttgttt atccaagtcc tctctaacac
     8221 ttctaacatt atgaatatgc acatgttgac cactttttat ttcctgattt gcttctccta
     8281 tatgttcacc atatttagta actttatcac ctttggctat atcttttata gctaatttat
     8341 gataaatagt tatatcatcc agtgctgtaa tcgtttttat tgttttgtct tttaatttaa
     8401 aactaatttc actaccttta gctattgctt caatagctac tgcaacatta tctttttcat
     8461 caattataac tgcatttatc attattcttg ctctccttta taaataatat aattttatta
     8521 atatcctaaa acctaattaa agaatttact attttaccaa caactcactg taatataaat
     8581 taagctgtta ttgtaccatc ctcattttgt tttgggaact taggacatcc atacttctta
     8641 gcccaccaac tagttataag aggtaccaat attgcagtga caactactgc ggctgccacc
     8701 tgtgttgtag ctgttgcaac atatggttgc catgatgggt caactaatgc aacagcagca
     8761 ggtacagcaa ttgcatttcc agcagttgta gctacagccc atcctgcata tcctggacgt
     8821 tttcctataa atttatcaca aaatactata aatatacctc ctacaaatac agatattaat
     8881 ccaagtagta ctcctgataa acctcctttt aatatacttg caagatttat gctactacca
     8941 agtgcaaatc ctacaaaagg tacgagtaaa ttacaccctg gttctaaaaa ctctttcatt
     9001 tttttgtcaa aatttcctat tatcatacca acgagtattg gcactattgc agccaataat
     9061 gacaacaaag gtacatttgc aagacctgaa gtcccaagag ctatcagtgt aaaaaatgga
     9121 ccatcattta atgtaagtaa actcatagtt gcacaatctg tttcatctcc atatgaagtc
     9181 atcaatgaaa gatatatact accattacta tttgtaactg cgcttataac tgctaaagtt
     9241 gtaagaccaa gtactccatc cattccaaat aactttccta taagtatacc tatcaaagca
     9301 cctatagcaa atttagaacc aagaagtata ccaccccttt ttaaaacttt tggcatttct
     9361 ctaaattgaa gctgagttcc caagcatacc agttgaactc caattatggt tgcagaccca
     9421 acacttgaaa atactgctgt cgtaaacgaa cctatttgta caatatctgg gcaaaaggta
     9481 ttaatgaaag ccgctataaa cattggcact atcatcatac ctgcaggaat ttttttaata
     9541 aaatccatta tcataaagtt aatcctccta aaacatggta tttaattact cttattaagt
     9601 ttttagcttt aattctaacg gccgttttag ttcgtattta agaactacgt ttttaattac
     9661 gaatctttga attaatgata gcattttcct atttatgagt caataaaaaa aataaatttt
     9721 tgtcaaaatt ttttcaactt ttctgataag acattatgta ttatcaaatg acttccttat
     9781 atgcaaaaat acatagtatt ta
//
LOCUS       DAMKOJ010000110         9708 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000110 DAMKOJ010000000
VERSION     DAMKOJ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9708
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.119"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            256..1317
                     /locus_tag="PC592_003173"
     CDS             256..1317
                     /locus_tag="PC592_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF4057110.1"
                     /translation="MRDFLKNYKSSIILLACTIIGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKSTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKSLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     VGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIVMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAVMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1330..1527
                     /locus_tag="PC592_003174"
     CDS             1330..1527
                     /locus_tag="PC592_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF4057111.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(1677..2381)
                     /locus_tag="PC592_003175"
     CDS             complement(1677..2381)
                     /locus_tag="PC592_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF4057112.1"
                     /translation="MQQGSDYLKKILEKHIDLLKKIPLFEGIKSDELEAMLECLGVVD
                     KIYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEILFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSNKFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFYKNKFEIFCFQK"
     gene            2542..3267
                     /locus_tag="PC592_003176"
     CDS             2542..3267
                     /locus_tag="PC592_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4057113.1"
                     /translation="MMRKIIKIDEKKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKTQNKNLACGCPGSQSKSINRE
                     GSNNASISNDVVETKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEIDYTEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3326..4918
                     /gene="hcp"
                     /locus_tag="PC592_003177"
                     /gene_synonym="priS"
     CDS             3326..4918
                     /gene="hcp"
                     /locus_tag="PC592_003177"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDF4057114.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGDTANLQDELTGVLIGL
                     SRATIGNKNRPTSKTDKIMIEGLFTTITNVSFDDEAIKRQIEKTEIEKSKIVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYKEDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGDIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5296..6201
                     /locus_tag="PC592_003178"
     CDS             5296..6201
                     /locus_tag="PC592_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF4057115.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKHIFNKSYTEMLRPKYENKNLKEVLLRIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6325..7278
                     /gene="msrA"
                     /locus_tag="PC592_003179"
     CDS             6325..7278
                     /gene="msrA"
                     /locus_tag="PC592_003179"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDF4057116.1"
                     /translation="MVKLATFAGGCFWCMVKPFDKYDGVIKVISGYTGGHIENPTYQE
                     VCSGTTGHVEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESKEHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPKEDMETLGYGEYLKLFE"
     gene            7431..8561
                     /locus_tag="PC592_003180"
     CDS             7431..8561
                     /locus_tag="PC592_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4057117.1"
                     /translation="MNLKDFNGKKLKSARTFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINVVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPSRKVMSDININDIESLAYKTREFWDLNSTPIVNMVNLLES
                     KGIIISGMNVDRKWATIFTQKQRISKESKYIISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPNKQFSEDEYACAFLLPKDIFLEDLIHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LGKINYKKYNYLVNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLDEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDSKK"
     gene            complement(8678..9646)
                     /locus_tag="PC592_003181"
     CDS             complement(8678..9646)
                     /locus_tag="PC592_003181"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDF4057118.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFIVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRLLSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPNTYSNLDLP
                     SIVEKNKKTGINIINGKDCTEFGIGTALVEIVKAILHNEKKILPVSTLLENQYNERNV
                     FASVPCVIGKDGIEEIIEINMTEDEQNEFNKSCSVLREYIALSKTL"
BASE COUNT         3725 a         1126 c         1638 g         3219 t
ORIGIN      
        1 gtttgtttta ttaaaatcaa tctagaaaaa aagttttaaa agcagaattt tattaatatt
       61 tatatatagg tatgaactat taaaaaaaga ttaaagatac aaaaaaacta tagaaattga
      121 catatattcc agtatttgct aaagtagctg ttggggaaaa ttacaaaaac tattaatgcg
      181 cattagataa tttactttaa tttttttagg gtttggggta atttataata taaaatatta
      241 gaaaggaaaa tataaatgag ggacttttta aaaaattata agtcatcaat tatactttta
      301 gcatgtacta taataggggc gatagtagga ttagtacttg gtccaaaagc ttcaatacta
      361 aaaccatttg gagatttatt cataaatgct ctcttaatga tagtagtacc attagttttt
      421 cttagtgttt cttcaggtgt tgctagtata aaaaatatgg aacgctttgg aaaaataatg
      481 aagagtacag ctatagtatt tatgggaaca acacttgtaa ttgcattttt aggtattaca
      541 tctgcattat tatttaatcc atctaaagga ttagatgtat caagtgtaaa aagtttaatg
      601 gtggctcaag atgcagaaac tttagaatca aaaggaacat tattagacca agtagtatca
      661 agtattacag ttaaaaattt tggagattta ttttccagta gcaatttact acaattagtt
      721 atatttgcag ttttagttgg aacagcaata gctatgatgg gagatagggg aaatacaata
      781 agaaagcttt tatcagaagg aacggaagca atattaaaag tagtaagtat agtcatgctt
      841 tatgctccta tagggctagg atgttataca gctacaataa ttggggaact tggaagcaaa
      901 ataattcaag gatatgtaag ggtgtttgta atttattcgc taacagcagt catgtatttc
      961 ttattatttt acagtctata tgctttttta tctgcaggaa aacaagggtt tagacaattc
     1021 tggagaaatg ctataaaacc aatagcaacg gcactagcta cttcttcaag ttcagcatgt
     1081 ataccatcaa atttagaagc tagtaaaaat ataggagttc ctgatgatat atcagaaaca
     1141 gttatacctc ttggaataaa tatacataaa gatgggtcag ttttagcagt aataataaaa
     1201 gtggcatttt tatcaggtat tttaggtagt ggaatggcaa atccagcaac gataggtcaa
     1261 ttatttataa ctgtatttgt tgttggagta tttatggctc ctgtagcagg tggctgactt
     1321 attggtgaga tgctcgtggt tagcatcttc ggttttccag tggaggcaat tccattgtta
     1381 acagttataa ctactataac tgatattcct aatactatat taaatacaac tggaaataca
     1441 gtatcatcaa tgttagtttc aagattagta gaaggaaaag attggcttat agacaaaaca
     1501 gcaattacta caaagaaaat aagctaatta tatacttaat taataaagtt aatagatatc
     1561 ttaattttaa taaattagat atctattaac tttttaaata aaaatataaa tttaagattc
     1621 aaatatgata tttataattt gaattaacta atataatata tgtttaaata tctagtttat
     1681 ttttgaaagc aaaagatttc aaacttattt ttataaaaag ataacaagcc ttcatcccgc
     1741 atcttaccaa gttctcttga catagaactt ctgtcaacac acaaaaaatc agccatttca
     1801 tttcttgaaa aagggattgt aaacttgttg ctacctgttt gttctatctg ctttgaaaaa
     1861 tacataagca atttttcacg agttgtttta cgagaaagca attctatttt attgtggagt
     1921 aaaatatttt tttcggctat taattgtagc atgttttcaa caagtctatt atgaaataca
     1981 catgtagatg aacaaatacc agttacactt ttaaacttta taaataaaat ttcacaagaa
     2041 gatgttgtgg tcactgtgac attactttta tgtagtctag tacatgcaaa cacctctcca
     2101 aataaatctc caggtaagag ttcagctacg atatttctat taccttcaat atcttccttt
     2161 attatatgtg cacttccttt aagcataatt cctattgaag taacctcact tccaacagag
     2221 aatattatgc tatcttttgg ataaatcttg tctacaacac ctaaacattc taacattgct
     2281 tcaagttcat cacttttaat tccttcaaat agaggaattt tttttagtag gtctatgtgt
     2341 ttttctaaaa tttttttcaa ataatcactt ccttgttgca tatgcaaccg ataatttgtt
     2401 tttattgtac tatactaagt ttataaaagc aaggagataa aaatactact ataagaaatt
     2461 tgaaataaaa agatgtagtc ttaaaaataa atatataaga agtaaatatt taaaattaaa
     2521 aaaatttatg aggtgatata aatgatgaga aaaataatta aaattgatga gaaaaaatgt
     2581 aatggttgtg gactatgtgt tgaagcttgt catgaagaag ctataggaat ggtaaatgga
     2641 aaagcaaaac ttttaagaga tgactattgt gatgggctgg gagattgcct accaacttgt
     2701 ccaacgaatg caatttcatt tgagtataga gaagcagcag aatatgatga agcagcagta
     2761 aaagcgaata tggaagcaaa aaaaacacaa aataaaaatt tagcatgtgg atgtccaggt
     2821 tctcagtcta agtccataaa tagagagggt tcaaataatg catctataag caatgacgta
     2881 gtagagacaa aaggttctca acttaaccaa tggccagttc aaataaaatt agtaccaact
     2941 aatgcatctt atttaaagaa tgcaagcctt ttaatagcag cagattgtac agcatatgca
     3001 tatggaaact ttcataataa atttatgaaa aataaggtta cattaatcgg atgccctaaa
     3061 cttgatgaaa ttgactatac tgaaaaactt acagagattt taaaagaaaa tgatattaaa
     3121 aatatagtag taacacgtat ggaagttcct tgctgtggtg gtatagtaaa tgctgttaag
     3181 acagctctac aaaatagtgg aaaaatgata ccatggcaaa tagttactat atctgtagat
     3241 ggaaaaattg tggatggaga aatttaatta agtgaattac agaaaaattt aataaatttt
     3301 aataaacaaa agggaggaat aaaaaatgga aaaaatgttt tgttttcaat gtgaacaaac
     3361 agcaggaggt aaaggttgta ctataaatgg tgtttgtggt aaaaaggggg atacagctaa
     3421 cttacaagac gaacttacag gagtgttgat tggtctttca agagcaacta ttggaaataa
     3481 gaatagacca acaagtaaaa cagataaaat tatgatagag gggttattca ctactataac
     3541 aaatgtaagt tttgatgatg aggctataaa aagacaaatt gaaaaaacag agatagaaaa
     3601 aagtaaaatt gtacctagat gttcagattg ctcaacaact tgtaatagaa atgataacta
     3661 tgatatgaaa gatttatgga atgataatga agatatacgt tcattaaaat cattaatatt
     3721 atttggatta agaggtatgg ctgcctatgc atatcatgcc atggtactag gttatacgga
     3781 caaagacgta aatgagtttt tctatgaagg attaatagca gttggaggag acttgtctat
     3841 tgacgaactt ttaggtttag ttatgaaaac tggagaaata aacttaaaat gtatggaatt
     3901 gcttgataga gcaaatactg aaacttatgg aacgccagaa ccgactcagg tatctatgaa
     3961 aatcgagaaa ggaccattta ttgtagttac aggacatgac ctttatgatt tacacaaatt
     4021 attagaacaa acaaaagata agggtataaa tatatatact catggtgagt tattaccagc
     4081 acatgcatac ccaaaattaa aagaatataa acatctaaaa ggtaattttg gtacagcatg
     4141 gcaaaatcaa caaaaagaat ttgataatat tcctgctcca atactattta caacaaattg
     4201 tttaatgcct gttaaagata gttatagaga tagagtattt actacagaag tagttgctta
     4261 tccaggtatg gttcatattg atgaagacaa agatttttct agtgtaatag aaaaagccct
     4321 tgaacttgga ggatataaag aagatgttca tatgactggt attaatggag gagatacatt
     4381 aactactggt tttgcaagag gtacagtttc atctgtacaa gataaagtag tagatgctgt
     4441 aaagagtgga gatataagac actttttatt ggttggaggt tgtgatggtg caaaacctgg
     4501 aagaaattat tacactgaat ttgtaaaaca agctcctaaa gatactgtta tattgacact
     4561 tgcatgtgga aaatatagat ttaatgattt agaccttgga gatataggtg gcttacctcg
     4621 tttaatggat atggggcaat gtaacgatgc ttatagtgca attaaagtgg cagtttcatt
     4681 ggcaaatgct tttgaatgtg gagtaaatga tttacctctt agtatggtac tatcatggta
     4741 tgaacagaaa gctgtttgta tacttcttac attacttcac ttaggtatca aaaatatcta
     4801 tataggacct tctttaccag cattcttatc taagaatgta ttagatatat tggttgataa
     4861 atttgcattg acgcctatat ctactcctga agaagatatg aagaagattt taggataaaa
     4921 aaataaatat atctatactt aaatctattt atagttaaaa tatttttaag tatagatgca
     4981 attaagataa ggggttaaac ttaaaatttg attaaaaaaa tcaattttga gacaaccctt
     5041 tatttatttt ttgtaataat tgaaaattaa acctgctttt agtatattct ttttaggaat
     5101 ccttgtatta aacttataat gcttagatat ataatatctt atagatttta ttttaagtag
     5161 taaaattttt aatggaattt aaatattaaa aaaggaacat tgtaatatgt aacttgcata
     5221 aaatatatat actatagtga aattatttta attaaaattt aaaatagaaa gtgttttatg
     5281 tgggggtata tgtatatgaa aaattctaat ttcaatatat tggcatttga tggtggtgga
     5341 ttaaaaggag cattgagtat atccatactt gagaggatag taaaagagta tccaaatcta
     5401 ttaaataata taaatatgtt tggaggaaca tctacaggaa gtctaattgc attaggactt
     5461 gcatatggtg taagcccgaa agagataaaa gagctttact caatcgaaaa ttcaaaacat
     5521 atttttaata aaagttatac agaaatgctc agaccaaagt atgaaaataa aaatttaaaa
     5581 gaagttttat taaggatatt tccagaggaa ctagaattaa aagatttaaa taaattagta
     5641 atgataccaa gtttttatat aggaaatgaa gaaaatgcat ggaaaccagt gttttataac
     5701 aatatgccaa attcttttac aaagactagt aaagtagtag atgtagcaat ggcaagcagt
     5761 gctgcaccag tgttttttcc aacatataat cgccatgttg atggaggaat aatagcaact
     5821 gacccaagtc tagcgtgtat aattcatgcc attgacagtg gatttaagct taaaaataca
     5881 agactttttt cgataggaac tggatatgta tataatagta taaaggcaga cactactgaa
     5941 tggggagcta ttgactggat aattaataaa gaacctgatt taccaattat atctattaca
     6001 ttagaaggaa attctcaaat gagtcagtta ttttctcaaa aacttcttgg agataattac
     6061 tatagattaa atcctaagat ggaaaaagat gtagctatgg atgattgtga tgcgttagaa
     6121 tatttaatgt ctttaggaga aaattgtgat ataaaagatg cttttgggtg gataaagaaa
     6181 aagagctttt atagaaatta gattcaattt aaaattgtat ttttacacat gatttcattg
     6241 aatatgtaaa aataataaaa tgcagattat taagttactt cttagggaat aaataaaata
     6301 taatttattt aaggagtgat gaaaatggta aaacttgcta cttttgcagg tggatgtttt
     6361 tggtgtatgg taaaaccttt tgataagtat gatggagtta ttaaagtaat ttctggatat
     6421 acaggtggtc atattgaaaa tcctacatat caagaggtgt gttcgggaac aactggtcat
     6481 gttgaagcta ttcaaataac ttatgatgat gatataataa gttatgatga gctactgaat
     6541 atattttgga aacagattaa tcctactgat gatggtggac aatttggtga taggggaact
     6601 caatataaga ctgctatatt ttatcatgat gaagagcaaa aaaatatagc tttagagtca
     6661 aaagaacatc tagaaaatag taaaatattc gatagtaaaa tagtaactga tataattcca
     6721 gcaactaagt tctatgaagc agaagaaaat catcaggatt attataagaa aagaccatta
     6781 aactacaata tgtattataa agggtctggt agatataatt ttgtaaaaag tcattgggat
     6841 ggaaacaata taaatagaga agagttaaaa aagactttaa ctcctataca atttgaagtc
     6901 actcaaaatg atatgacaga ggtacctttt gaaaatgagt attatgataa taacaaagaa
     6961 ggaatttatg ttgatattgt aagtggagaa gtgctatttt cttcaaaaga taaatttgat
     7021 tctggatgtg ggtggccaag tttttcaaag ccagttatag ataaatctat tattgagaga
     7081 agtgattttt ctcaaggtat gtacagagtt gaggtaagaa gtgctaaagg aaattctcat
     7141 ttaggtcatg tatttgatga tggtccaaaa gagcttggag gtttaagata ttgtataaat
     7201 tctgcttctc ttaaatttat acctaaagaa gatatggaaa ctttggggta tggagaatat
     7261 ttaaaacttt ttgagtaatt ggaactattt attataaact tagctaaaag gtgaaaatat
     7321 aagaaaatat tttcaccttt tgtttttttg tcaataatat gataaattat taattgtaat
     7381 cttatttata ccagtagatt aagaatttaa ttttgaaaga gagaaaacaa atgaatttaa
     7441 aagactttaa tggaaagaaa ttgaaatcag ctagaacttt tagagcaaag acgatagaac
     7501 agttgtctaa agaaactaaa ataaacaaaa aagatttaaa agcttttgag gaaaataagt
     7561 atgtcccaaa tatagaaaat acattaaaat tatctaatat attaaatttt ccaaaagagt
     7621 atttttataa aaatgaaaat ataaatgtag ttgtagagga tagccacttt aatcctcaat
     7681 ctaaactacc tagagtagaa gaaatttctt atagagaaaa aataattata atacataaaa
     7741 tatattcttt tatggagaat tatattaagt ttccaaaaga aaacttacca agtagaaaag
     7801 taatgtcaga tattaatata aatgatatag aatctcttgc atataagact agagagtttt
     7861 gggatttaaa tagtactcca atagtaaata tggtaaattt gttagagtct aaagggatta
     7921 taatatcagg tatgaatgta gatagaaaat gggcaactat ttttactcaa aaacagagaa
     7981 ttagtaagga atctaaatat ataatatctc tcggtaatga taaaaagtca gcatcaatta
     8041 gaaattatac tttggcatgt gagcttgggt atataatatc aagtgaatta agaataccaa
     8101 ataagcaatt ttcagaagat gagtatgcat gtgcattttt attgccaaaa gatatttttt
     8161 tagaagattt gattcatcca gaagatttgg attattatgt agaactaaag aaaaaatgga
     8221 ttgtacctat atctgctatg atttttagag cgtataatct aggaaaaata aattacaaaa
     8281 aatataatta tcttgtgaat gaaatggata aaaaaggctg gttaatagaa gaaccactag
     8341 acaaaatgaa aggttcaagc ccaacgtatt taaaaagagc agttgaatta ttgatagaaa
     8401 ataaaataat gagcgtaaat agtatagtat caagtttaga tgaatttgga ataaatcttt
     8461 atccagaaga cttagaatta ttgatgggat taaaaaaagg actgttatcg caagaggtaa
     8521 ataaaaaaag taaagttata aaatttgata gtaaaaaata ggttgatatt ttagcattaa
     8581 aattaaaagc aggtataaat gatttaaaca ttaatttaat taaaagtctt ttcaatgagt
     8641 catttacctg cttttagtgt aaaaaagaat cttgaatcta aagtgttttt gaaagtgcaa
     8701 tatattctct taaaacagag caagatttat taaattcgtt ttgctcatct tcagtcatat
     8761 tgatttcaat aatttcttca ataccatctt ttcctataac acatggaaca cttgcaaata
     8821 catttctttc attatattga ttttctagta atgtagaaac tggaagaatt tttttctcat
     8881 tatgtagtat agcttttaca atttctacta aagcagtacc tataccaaat tctgtacaat
     8941 ctttaccatt tattatattt atccctgttt ttttattttt ttcaactatt gatggtaggt
     9001 ctaaattgct ataagtattt gggttatcct ttatcatgtc caagattggt ttaccaccaa
     9061 ttgaaacatg agaccaagga accatttgag aatctccatg ttcacccata gaataagctt
     9121 gaattgattg ttgagcgatt ccagtttctt cagataaaag ccttctaagt cttgttgaat
     9181 ctaaagctgt gccagttcca atgactttgt ttttaggaaa gccagatttt tcccaaatat
     9241 aatttgtaac tacatcaaca ggattagata tgactataaa tataccatca aagccagaat
     9301 caactatggg ttttactata gattttatca ttccaatagt tggtcttagt aaatctaatc
     9361 tagttgtatt ttgtctacgt aaaggacctt ctgaagagtc tgcaacactt atcactacta
     9421 tatcagaatc tttacagtca gaaaaagttc ctttttctat atgtactttg tgtggcagat
     9481 atgaaactgc atcagctaaa tctaaagctt gagcttttga tttagattca tctatatcaa
     9541 tcataaagag ttcatcacaa actccttgag ttattaaact gaatccacaa tgagagccaa
     9601 catgccctga acctacaata gatatttttc ttggctttat tgccatttta aatcactccc
     9661 cctaaaataa cgatacattt ataagaatat tatatattat aaagagat
//
LOCUS       DAMKOJ010000111         9704 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000111 DAMKOJ010000000
VERSION     DAMKOJ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9704
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.120"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            192..1082
                     /locus_tag="PC592_003182"
     CDS             192..1082
                     /locus_tag="PC592_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF4057119.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            1300..2586
                     /locus_tag="PC592_003183"
     CDS             1300..2586
                     /locus_tag="PC592_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF4057120.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKKDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHINDLCDKYKDRLFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTKENLLDILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKAFGKNEEIVINPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDNAKQMTKEIEETIF"
     gene            complement(2675..3118)
                     /locus_tag="PC592_003184"
     CDS             complement(2675..3118)
                     /locus_tag="PC592_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HDF4057121.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFSITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDKDKKKP"
     gene            complement(3142..3936)
                     /locus_tag="PC592_003185"
     CDS             complement(3142..3936)
                     /locus_tag="PC592_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HDF4057122.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEIAAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKRIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(4502..4978)
                     /locus_tag="PC592_003186"
     CDS             complement(4502..4978)
                     /locus_tag="PC592_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF4057123.1"
                     /translation="MKEILINPIGKIRIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTTVQIISIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSIDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(5079..6248)
                     /locus_tag="PC592_003187"
     CDS             complement(5079..6248)
                     /locus_tag="PC592_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4057124.1"
                     /translation="MLNIRTLCNEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVNPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLKNPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIKGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIKE
                     ICDFTCKTFGGSISVEIEEGYPALINSNYLVDYVKQNAVELFGKENIILKDAPTLGAE
                     DFSYFLKHCEGAFYHLGCANREKNIISPLHTSTFDIDEGCLITGVMLHVKNVLAF"
     gene            6411..7274
                     /locus_tag="PC592_003188"
     CDS             6411..7274
                     /locus_tag="PC592_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDF4057125.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLSYKGYL
                     AGNDDIRARDIEGMFLDKDVDMIMCLRGGYGTTRILDKINYEIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVAKWDEFTYKSLVNALEFKDDLYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEEKDLIELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            7345..7938
                     /locus_tag="PC592_003189"
     CDS             7345..7938
                     /locus_tag="PC592_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HDF4057126.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(8190..8825)
                     /locus_tag="PC592_003190"
     CDS             complement(8190..8825)
                     /locus_tag="PC592_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF4057127.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAK
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTSKSIELLSYPVHCLENDIES
                     ELVDELKSIENLKILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(8905..9636)
                     /locus_tag="PC592_003191"
     CDS             complement(8905..9636)
                     /locus_tag="PC592_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF4057128.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLEIDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLKKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTD
                     LILNIELKTDKVNYPNIEKDVLELILKYNIKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIEICHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLQSKQYR"
BASE COUNT         3662 a         1169 c         1439 g         3434 t
ORIGIN      
        1 atccataaaa acatataact ttttaactat aattattatt gttattaatt gaaaagattt
       61 attagttact tgacatagtt tacactttta attatagtat aaattggaat atttagataa
      121 ttattattta atgtacaagc taagttttta attaatacgg ctttatacat ttatatagaa
      181 aagaggtacg tatgagtagc acaatcaaat caaatcgaat aaaaggtata atgtttataa
      241 tagcatcagc tcttggcttt gcaatgatgt ctgcatttgt aaaactagct ggagatttac
      301 caagttttca aaaagtgttc tttagaaatc tggtatcagc tataatagct ttttggctta
      361 tcataaaaca taaaggtagt ctaactggga aaaaagaaaa tttaaaagta cttttatata
      421 ggtcaatatt tggaactcta ggagttatat ttaactacta tgcaattgac aagttgatgc
      481 tttcagacgc taatatgcta aataaaatga gtcctttcct tgtagttata ttttgtgcaa
      541 ttgctttaaa agaaaaaata aatgtaaagc agataggagc tattataatt gcatttatag
      601 gagctttatt cataataaaa ccaacattta gtgtagaagt aattccatat cttggaggaa
      661 ttgcaggagc tgtatttgca gcaatggcat atacttgttt aagagttctt ggagatagag
      721 aagattacta tacaatcgta tttttctttt cggttttttc attagttact gtagggccaa
      781 ttgcttttgc agtatatgaa ccaatgactc ttatgcaact tatatatcta ttactaggtg
      841 gagtatttgc aagcctaggt caatttggaa taactctagc atataaatat gcacctgcta
      901 aggaaatatc tatattcgac tacagtaata taatcttttc agcaatttta agtatattct
      961 tattcaatgt ttatccagat atgttaagtg ttgttggata tttaatagta ttttcagcag
     1021 cattttatat gtttttatat aataagaaat tagataaatt agacaaagaa aagaagaagt
     1081 aagctagata aaagtgtttt tataatttgt attgaatatt taagtctttg tattaaaatt
     1141 aaagaaaatt taattaaaaa tgtttggtat attaacttat aacagcagtt aaaattgaaa
     1201 aattataact gctgtttctt ttattaaaaa tatccaaata tccgtaaaaa tagactataa
     1261 tagagtagta taaataatat aaaggggata aattaaagta tggaaaaagt gaaagttgct
     1321 gtgattggag ctggtaatag aggaacgtat gcatatgctc catatattta tgaaaattct
     1381 gatgtatgtg aaatagttgc tgtagcagag cctaaaaaag gaagacgaga actatttaca
     1441 caaaaatata acctagatag taaaaatgta tttgaaactt tagaagactt ttttaaaaag
     1501 gacaagatgg cagatgcagt tataatagct acaaatgatg atagacatta tgatgtagca
     1561 aaactagctc ttgaaaaagg ttatcatgta ttattagaaa agccaatgtc taatagttta
     1621 gatggtttgg tacatataaa tgacctatgt gataagtata aagataggct ttttatgatt
     1681 tgtcatgtat tgaggtattc tccattttat aacaaattaa aagagattgt agaaagtaaa
     1741 aaattaggag aactagttag tatacaatat aatgaaaata taggatattg gcattttgca
     1801 catagcttta ctagggggaa ttggagaaat agcaatgaaa caagtccttt aattttagcc
     1861 aagagttgtc atgatatgga tattttatta tatttagtag gaagtagatg taaaaaaata
     1921 tctgcatttg ggagcttaaa gcatcttaat aaccaaaatg ctagtggaga gatggcacaa
     1981 aattgtcttc agtgtttagt agaaaaaaaa tgtccatatt cagcaaagag aatttattta
     2041 gaaaaagata gaagtataaa tagagctgtc catataaatc caactaaaga gaatttattg
     2101 gatatactta agacaagtcc atatggaaga tgtgtttata gatgcgacaa taatgttgta
     2161 gataatatgg taaatatatt acagtttgaa aatggagtga cggctacttt taatttatgt
     2221 gcatttacta aagaaaatgg aagaactata aagttaatgt ttagccatgg tgaagttggt
     2281 ggagatttaa ataaaaatga gataagaatt aaagcatttg gaaaaaatga agaaatagtt
     2341 ataaatccat caaatcaaca gaatatggta gaggaatacg atagaaatct tatagctgaa
     2401 tttattaaat tagtttcaaa taaagaacta gaaaagggta gagtagcagc aaaagaagct
     2461 atacaaagtc atgtaatggc atttgcagca gaatactcta gggttagtga tgaggtagtg
     2521 tatatagaag aattttttga taatgctaag caaatgacta aagagataga agaaactata
     2581 ttttaattaa taaaaattta ttaaataaaa taaagataga ttaagtaata gaaatacgaa
     2641 aatatgtatt ctattaagaa atctatcttt tttattaagg ttttttctta tctttatcaa
     2701 aaaaatccat acattcggac aaaagataag aaagtaaagc gaataagatt tctgtactta
     2761 aaggaatcgt tactgaatcc ataaaggtat caattatgtt catagctaga aaagttagta
     2821 taaaatcaat tataaattcg caaagtttat atattgaata tggtaatttg tttacatatc
     2881 tgaatatatc taaaatagta gtgcatagaa aatcaattgg agtggttata caaaaatata
     2941 ttaaaaagaa aattaataca gctccaagag acttatattc aaatcctaag aatgataaga
     3001 agccaattcc tataaccgtg aaaatacaaa aagttatact aaaaaaaaca gcaaaaaata
     3061 aaaatacaga aataaattcg cctaaaggaa tccttctttt attacttatc ttaatcaacc
     3121 ccttaattta tgacatgaaa cttatataaa taataacatt cttaaaaatt cataatagtc
     3181 ctctgtttca aatagtactg tctgagaatc tatttttttc atatttggat aaaaagaggc
     3241 cttaaaagct ttataatgtt ctctaaattt tatttctatc ttaaatttat ctggcaattt
     3301 tattaagtgt ctagataaat ctccagataa agcttttttg acaccttttt cgattctttt
     3361 tagtgcaagg tttggatgga ttgaaattga accatttcca attccttttg acacaggaac
     3421 agtgactata tttggattta gtttttttgc actctcacaa agcatttcat ctccacttaa
     3481 aaatgctaca ggaacattat aatatgcagc aatataagca tttatagtaa attcagatgc
     3541 tatttcatca tttattttaa aataatcata atcaatatcc atagtatgag aaagtggatt
     3601 accattacaa gtagctccag aatgatagcc agtgaatata catgcatcaa agctttcatc
     3661 aatcccagcc atcataacta gtgggtcttt ggtccatccc ctaagtattt tgacgttttc
     3721 aggtaaaata tttggattaa tatttctacc actatcatgt gcatctttaa caagtatctc
     3781 atgcacacca gattgagtag ctccatcaca tgctgctgct atctctttac tcatttgtgt
     3841 tctatagtgt tgtgaaaatt cacattcaag ttttgtctca tcccaattta caataccaca
     3901 agtaccttct atatcagcac ttaaatataa tttcataata tataccccct tatgtttatt
     3961 attaatgata ataacagata acagaaaata cataatcaat aaagggcata aaaacattat
     4021 gtcttactat taattattat taaatctgta actgaaaaat aactaaactg gtattaaaaa
     4081 atataacact atgtgtcatt tatttatata gttttttata tctgatgttt atataaaatt
     4141 gtaacatata agtggttaca tttactagtt taacatagtt aaaatagtta ggtattattt
     4201 ttaatttaaa ttgattatta taaaatcgtg gagtaaaaga aaaatttaat ttattaaaaa
     4261 tgcacgaaat gttttatcct taacacaatg ctaaattaaa ctcaaaacga aataatagaa
     4321 aaatcttatg ttcttagaaa gaatgtgaat gatttaaggg aaaaatagaa atttattata
     4381 taatattagg ctgtattata taatacagcc taatattata tgtatatgtg acataaaatc
     4441 ttggtaagtg taaataaaat aaatgtggaa aacaagttaa tgaaatcaag aaaaaagtaa
     4501 tttaaaattc aatttcatct tcccaattaa attctcctga tttttctaca ctcttaggcc
     4561 agtgactaca ccattttgga actgacggat tttcaaccct atcaatgctt ggagtatatg
     4621 gctttaagtc aataacagga ctattatcat tagcatcaat atatggtatt tttattatac
     4681 cattttcatg gtctatactg ataatttgta cagtagtcaa tgctattggg ttgggtctta
     4741 taggtgacct tgttgcaaat attcctataa catctggccc acttttataa ggtttaggag
     4801 tttctaaaat acttcttagt tcaggattat cgaacccatc agcccaccaa aatacattta
     4861 agtggctgaa gtcgtcgagt tcatttaatg caggtacata ctttttgtct aatttaataa
     4921 agacctcctc gccttgaata cgtattttac ctataggatt tattaatatt tctttcataa
     4981 tattacctcc aattaattaa tttatcattt gtaattttag ggtataacat gacatcatgt
     5041 gagggtcaat ataaaataat aaataaaaat attaatattt aaaatgctaa tacatttttt
     5101 acatgaagca tgacaccagt aataagacaa ccttcgtcaa tatcaaaagt agaggtatgc
     5161 agaggggaaa taatgttttt ttctcgattt gcacaaccaa ggtggtaaaa agctccttca
     5221 caatgtttta gaaaatacga aaagtcttca gccccaagag taggtgcgtc tttaaggata
     5281 atattttctt ttccaaacaa ttctacagca ttttgcttga cgtaatctac tagatagttt
     5341 gaattgataa gagctgggta accttcctca atttcaacgg aaatactgcc tccaaatgtt
     5401 ttacaagtaa aatcacaaat ttctttaatt cgtttttttg aaaattctct agtttcagga
     5461 gtcaaggttc tcaaagtacc ccttataact actttgtcac aaactatatt ttctttgatt
     5521 ccacctttaa tttttcctag agaaataact acagaatcag ttggatttgt gttacgacta
     5581 acgattgtct gtagagctgt aataatatga gcagatataa cgatagcatc aataccttga
     5641 tgtggataag ctccatgaca ttttgaacca tgtacagtta attgaagtgt atcggtagaa
     5701 gcatttagag tgttgtattt taattcaatc agatttttgt tgatattggg atttacatga
     5761 agtccaaata tatattttac atttgggttt ttaagacatc catcttctat cataagttga
     5821 gctccaccaa tagtttcttc agcaggttga aaaaagaatt ttacgtttac atttaagtaa
     5881 tcctttaatt taaatagtat attacaagta cctagtaaaa tagcagtgtg tgcatcatga
     5941 ccgcatgcat gcatttttcc aatattaata gatttataag aataattaag ttcctctgtt
     6001 ataggtaagg catctatatc agctcttatt gcaactgttt caaagtttgg atttacgttg
     6061 atgtatgcag ttatccctgt atgattctta tattcaatat aatttatacc tatttcattt
     6121 aagtacttaa taattttttt cttagtttga aattcttcta gtccaagttc tggagtttta
     6181 tgtaaatctc ttcttatatt tataacccaa tcatttatct cattacaaag agttcttata
     6241 ttaagcataa aacacatcct aaccatatta aaaatttatt tttccttatt aattatatta
     6301 ttttatgtaa atcattattc tgtatcaagt acaaataaaa tatcttataa ttatattaga
     6361 gatatttagt atggagaaga atatatcatt ttataagaag aggtgtttaa atgttaggaa
     6421 taattgcgcc atctgggcca ttaagaaata caagtttgga ggaaataaag tttaacttag
     6481 aaagttatgg ttacgaagtt aagttttctg aaagttgtag tttaagttat aaaggttatt
     6541 tagctggtaa tgatgatatt agagcaagag atatagaagg gatgttttta gataaagatg
     6601 tagatatgat tatgtgttta agaggaggtt atggaacaac aagaatattg gataaaataa
     6661 actatgagat aataaaacaa aatccaaaac catttatagg tttttctgat ataacaggtt
     6721 taaatttagc tttttataaa aattgtggtc ttttaccata tcatggaata atggctgcca
     6781 atgtagctaa atgggatgaa tttacctata aatcattggt aaatgcttta gaatttaaag
     6841 atgacttata tttagaaaat ccaaaagaag aaaaaattta tactgtatgt gaaggtaaag
     6901 cagagggaat aataatggga ggaaatttat ccttaataat tgctacaatg ggaacaaaat
     6961 atgaaataga tgcaaaagat aaaattttgt ttattgagga aattggagaa cctcaatata
     7021 aactggatag aatgttaaca caactatatt cctcaggaaa gcttgaggaa tgtaatggta
     7081 taatttttgg agattttaag gattgtattg aagaaaaaga tttaatagaa ttactaatag
     7141 aatttgcaaa taaagtcaat aaaccttcta tatataatct tcaatcagga cattgtatac
     7201 caatgataac tattccttta ggcagaatgt gcgaattaga tgctacagaa aaaatcgtta
     7261 aattaaaaaa atagtgtgta tataaatata atagaaatat ggtataatct tatacaagta
     7321 aaaatttagc taggaggatg aaaaatgtct gatgatagaa taatagactt taacgaacta
     7381 aagaacaaag ttaaagattc tgatgtagat aaatttgagc aatacatata taacttatat
     7441 ttttctgtta tggatggaaa gatgtctatg gctgagtttt caagaaaaat attcgattat
     7501 atgagagata acaacatatc tcaagaaaaa tttatgaaaa tacaaaagca atttatggag
     7561 agatatggta tggacactga agaagtagaa aaacaactta gaaactttgg aatcgaccct
     7621 tctacagcag gttttatgag taataatact tccagcaaag tatctacaga agatttagag
     7681 tcatttaaga agagtgcagg attttatgaa aaatatggag aaaaaatcca accaaagagt
     7741 tgtataacaa catttataaa aaatgactta aatgatatta atgtaataat cgaccaagaa
     7801 aagataatgc tttgtagtga tagaaaaata aatcttatgg attcagaact aaatgagttt
     7861 ttattagaat ataagaatat gtttaataag aaaataaagg tagtaatgtg cgaaactaca
     7921 aataagtatg actattaaaa agtgaattta aatactgaag tagtatagat taatggtatt
     7981 atttaaaaat aaaaatcgca atttattatt ccttataaat ttttataagg agtatctaaa
     8041 ctgcgatttt ttatattgtg aagattagtc atagtagata atatttttaa attgtaatct
     8101 tatcattaaa actgtgtttt tctattagag gttttattaa aaatagttat ctgataattg
     8161 tatcatatgt gatgcaaagt attagagtat taacgaatct cttttaatac attaactcca
     8221 ttttgaatca tactattaaa aaatactaag tttaaaatct cagcagggtg aacgttagga
     8281 atatcataag tatctactaa attcataggt acaactatat ttttttcaat attatgctga
     8341 ttaaaatatg attttagagt tattgcaaat tgatatatac atatatctgt acaatcgcca
     8401 actataatta tattgtctat attatcaaaa tccaaatttt ctaatgcaaa aaatccatta
     8461 gtagaatttt taggaagaat ttttaggttt tctatcgatt taagttcatc aaccaattca
     8521 ctttctatat cattttccaa acagtgaaca ggataactca aaagttctat tgacttagaa
     8581 gtatgagaat cagtaaatgc tattactcta tttaatttgt ttgatatttt ttttgtaaac
     8641 atttcgattg gctttattaa agactctact ctaggagagt ataatgcacc ttgttttgca
     8701 aagccattat taacatcaat tataaataaa gcggttttac tcaagtcata attttctatt
     8761 ttttctattg gtagattatc taaattactc tttaaagctt caagttcatt taataagtta
     8821 tccatagtta tacctccaag ataaatttaa taaaattgta catattaatt atataaaagt
     8881 caaggagtgc aaactattgt gtaattagcg atattgtttt gattgtaaaa gatttgaagc
     8941 aatgtctgga tagttagtaa aaataccatc tacattgagt tttagacagt gtagtatatc
     9001 atcctcttca tttacagtat atacattgac accaagtaaa tttttatgac aaatttcaat
     9061 tagagattca tttactaaaa ctagaggtgg atgaaggtaa ctattaccca gaaatttagc
     9121 aaaattgact acattgttta taggtaaata acacaataat cctgttttta cactagggtc
     9181 taatttatga aagtttttta aactattgct gttgaaacta gatataagaa ctctattttt
     9241 tatattatac tttaaaataa gttctaaaac atctttttct atattgggat agtttacctt
     9301 atcagttttt agctctatat ttaaaataag gtctgtaggt gaaattagaa ttaatacttc
     9361 ttctaaagtt ggaattttac attctttatt gttttgatat ccttcaaaag atgagtttag
     9421 agtctttaac ttttttaaag taaagtcttt tacaaaacca tgtccattaa aagttctatc
     9481 aaccttttca tcatgaataa ctacaatttt tccatcctta gttctgtgga catcaagttc
     9541 tattccatat atatctatct ctaaacattt tttaaaagct agaatagtat tttctggata
     9601 ctttccacta aaccctctat gagcataaat attcatttat gtggctcctt tcaataaata
     9661 taacttatct tataaaaatt taattaatat aatatatcat attc
//
LOCUS       DAMKOJ010000112         9662 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.121, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000112 DAMKOJ010000000
VERSION     DAMKOJ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.121"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            170..1573
                     /locus_tag="PC592_003192"
     CDS             170..1573
                     /locus_tag="PC592_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF4057129.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKINMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1664..1904
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1947..2645
                     /locus_tag="PC592_003193"
     CDS             1947..2645
                     /locus_tag="PC592_003193"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDF4057130.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2668..3669
                     /gene="trpS"
                     /locus_tag="PC592_003194"
     CDS             2668..3669
                     /gene="trpS"
                     /locus_tag="PC592_003194"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDF4057131.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4321..6951)
                     /gene="cdtB"
                     /locus_tag="PC592_003195"
     CDS             complement(4321..6951)
                     /gene="cdtB"
                     /locus_tag="PC592_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin binding subunit
                     CdtB"
                     /protein_id="HDF4057132.1"
                     /translation="MKVQMRNKKVLSFLTLTAIVSQALAYPVYAQTSTSSHSDNKKEI
                     INEDILTNNGLMGYYFTDEHFKDLKLMAPIKDGNLKFEEKKVDKLLNKDKSNVKSIRW
                     TGRIIPSKDGEYTLSTDRDDILMQVNNESTISNTLKVNMKKGKEYKFRIELQDKNLGS
                     IDNLSSPNLYWELDGIKKIIPAENLFLRDYSNIEKNDPFIPNNNFFDPRLMSDWEDED
                     LDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEK
                     ASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTES
                     NTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINAN
                     VRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALN
                     TMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYIS
                     QIDSISASIILDTENESYERRVTAKNLQNPEDKTPELTIGEAIEKAFGATKKDGLLYF
                     NDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDD
                     YNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSKLKPYKRYVFSGYSKDPLTSN
                     SIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITE
                     LNSTPEILNEPEVKIPTDQEIIDAHKIYSADLNFNPSTGNAYINGMYFTPTQTNKEAL
                     DYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYK
                     KLRIYAITPDDRELLVLSVD"
     gene            complement(7004..8395)
                     /gene="cdtA"
                     /locus_tag="PC592_003196"
     CDS             complement(7004..8395)
                     /gene="cdtA"
                     /locus_tag="PC592_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin enzymatic subunit
                     CdtA"
                     /protein_id="HDF4057133.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSEKV
                     CNTTYKAPIERPEDFLKDKERAKEWERKEAERIEQKLERSEKEALESYKKDSVEINKY
                     SQTRNYFYDYQIEANSREKEYRELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTEN
                     QNEISLEKFNEFKETIQNKLFKQDGFKEISLYEPGKGDEEPTPLLMHLKLPRNTGMLP
                     YTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKA
                     NYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKR
                     EPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKPENIDAFKSKWEGQTLSYPNFISTSIG
                     SVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKISKIDSYKDG
                     AITKLIVDATLIP"
     gene            complement(8785..9531)
                     /gene="cdtR"
                     /locus_tag="PC592_003197"
                     /pseudo
     CDS             complement(8785..9531)
                     /gene="cdtR"
                     /locus_tag="PC592_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906004.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
BASE COUNT         3307 a         1261 c         1407 g         3687 t
ORIGIN      
        1 tttatcattt ttaataagat ttgatttcaa agtatttaaa atttattatt aaaattgttt
       61 ttgaacatga aaatattttg aaaaatatca gtttaataat aatgaatcta ttttattagt
      121 tttgaaatta aatttaaaac aattaatgga gaggagaaat taaattagga tggaaaagaa
      181 aaaaataggc ctatggagtt tggtatttat gaatgtatca gctttgtatg gtataagatg
      241 gatagctaag tctacagcat caagctttgg tttaggatta ggtgcaatac ctatgtggtt
      301 attattctca tttatatact ttgtaccagg agctttaatt tgtgctgaat tagcttctac
      361 atatcaaaaa ggtgatggag gtctttacga ttgggttaaa gaagcctttg gagaaaagta
      421 tggattttta gtttcttggt taaactggac agctaaaata ttttggtatt cttcattttt
      481 aactttctta gcagtaaatg tttcttatac aataggaaat ccagctcttg ctgataacaa
      541 gatgtttgta cttatattat ctttaataat attctgggca ttatctctta tagcaactaa
      601 aggaataagt tttacaaaaa tatttactaa tacaggtgca ttaggttcaa caataccaag
      661 tgctatactt ataatatttt catttgtagc agtatttgta ttgaaaaaac atgatatagc
      721 ttctacatac acaatagctt caatgactcc aaaaattaat atggatgcct ttgttgctat
      781 atcagctata atgtttggtt tagcaggagc agagactgct gctaacttca taacagaaat
      841 agataaacct gaaaagaact tccctaaggc aatattaata tcagctggaa tagtagcttc
      901 attatatgta ttaggttcaa ttgcaataac aatgataata ccaccagacc aaattactgc
      961 ttctaaaggt gtattagatg cactttctgc tgtttgtgcg tctttaggaa ttggttcttg
     1021 gttggttcaa ttaatagctt ttggtatagc tttttcagta ttaggagcaa tagttcttta
     1081 catagcgtca ccaataaaaa tgttatttgg tagtgttaaa aaaggaatat ttccagatag
     1141 tttggtagag gtaaatgaac acaagatacc ttctaaagca gttatacttc aagcaataat
     1201 agttactata atactattgg tgactacatt aatgccttct gttgatgcta tatacaatgt
     1261 tcttgtaact atgacagcat taactgcatt attcccatat gtattattat atgcttctta
     1321 tattaaacta agaaaagaga gaccagatga aattagacct tatactatgg caaaatcaac
     1381 aagtacttgc ctaggtttag caaaaatggt tttagttgta actgtagttg gtatattatt
     1441 atctgcagca ccagttatgc ctacatttgc tgaaaatgtt atatatgaga tagagatgat
     1501 tggtggaggt cttctagtta tattatctgg tctatggtta tggaatagat atgaaaagaa
     1561 aacagctaaa taaaatgtat tttaaaaatt tcttttggat attataatat atagttgaca
     1621 atttatagtg taaggaatat tataaaataa agaaattaat aaattaaatc ctgagataag
     1681 aaatagtaaa taaatatatt tttgcacaga gaattaagga tgctgagaac ttaataaaaa
     1741 gtatttattg aatgggtctt tgaggagtaa aatgaaatgt aatttaagat tacagagtat
     1801 ttgatatcgt gtatgcacgt tatagcatat attaagatat atatattcaa ttttgagtgt
     1861 atataaattt aggtggtacc acggaaaata tatccgtcct attgatttag gacggatttt
     1921 ttaatataga aaatttagga ggaaaaatga acgtaatagg aattataggt gcaatggatg
     1981 aagaagttag tattttagtt gatttaatgg atattagaga gactataaaa aaagctagct
     2041 tagaatttta taagggaatt ttggaaggta agaatgtagt attagtaaag tgtggtatag
     2101 gtaaggttaa ttctgctctt tgtgcccaga tactaataag cgaatttaag gttgatgcta
     2161 ttgttaatac aggtgttgca ggagctttaa atgaaaaact tgatgttaat gatatagtaa
     2221 tatcaactga tgctatacag tatgatgtag acactacagc atttggagac cctaagggag
     2281 ttataccaag aatgaagact tctgtattta aagcagatga aagacttata gatgctgctt
     2341 acaaatcttc tgtggaagaa gtaaagactc ataaagtatt aaaaggaaga gtagttacag
     2401 gagataaatt tataaattct aaagaattaa aagaagaact cgtaaatgat tttggtggat
     2461 attgtggaga aatggaaggt ggagctatag ctcatgtatg ctatttaaat aatactccat
     2521 tcgtaataat aagagcaatg tctgataagg cagatggaag tgctgatgtt acttatgatg
     2581 tatttgtaca tgatgctgct aataattcta aagacatagt tttaaatatg ttaaaatcaa
     2641 tataaatata taaggaggta caaaaaaatg agtgaaaaaa aagttatatt tagtggagca
     2701 cagccatcag gcaaaatgac tttaggaaat tatttaggag ctataaaaaa ctggactgaa
     2761 cttcaagata attatgattg ctattatagt atagttgatt tgcatgcaat aacagtacct
     2821 caggacccta aagttttaag agctaatgct atagagttgc ttgctcaata tatagcttgt
     2881 ggattagatc cagaaaaaaa tactatattt atacaatcac atgtcaaaga gcatgttgaa
     2941 cttatgtggg tattaaatac tatgacttat atgggtgaat taagtagaat gactcaattc
     3001 aaggataaat cacaaaagag tgaagcaaat ctaaatgcag gtttattcac atatccagtg
     3061 cttatggctg ctgacatatt gttgtatcaa actgacctag ttccagttgg ggatgaccaa
     3121 aagcaacatt tagagttagc tcgtgattta gcaaataggt ttaataatag attttcacct
     3181 acttttgtag ttccagaagg atactaccca aaaggtggag caagagtgat gagtttgcaa
     3241 gagccaacta aaaaaatgag taaatctgat tcaaatgaaa atgcatttat attattagca
     3301 gatgattcag actctataaa gagaaagata aaaagaagtg ttactgattc tttaggtgtt
     3361 gtaaaataca atgatgaaca acctggtatt aaaaatctaa ttgatatata ttctaattta
     3421 agtaaaaaga gtgtagaaga gattgtaaac atgtatgaag gaaagggtta tggcatattt
     3481 aaagaagatg tggctgaagt agtatcagaa gctttaagac ctataagaga aaaatatgtt
     3541 gaccttctta ataataaaga ttatttagaa aaaatatata gtatgggagc agaaaaagct
     3601 gaaaaacaag ctagaaaaac tcttagaaaa gtttataaaa aagtgggatt tatagagaga
     3661 agatactaat tattagctat ccttacttga taaataaatt ttaaagttat taaaaaagta
     3721 tatgatatga aagagagagt ctcaaagtaa acttttgttc atgaggcact cttttttgta
     3781 tgaaataaaa tatattttaa tcatttcaac aatgaaaaag aggattattt ctattttgag
     3841 acagtacctt ttgataataa aaaaagatga gcttttgctc atctcaaagg ggttagatta
     3901 ttcttacttt ggggaaagta gaataaaggt aaaagttaac tgatgtcaac tttgtctttt
     3961 ttgcatatca ctactgagca taaaaaaatc agaaaaccat agccttctga aacaacttct
     4021 aacatacatt gtattttata cccaatatgt aatttatgag ttaattttaa ctcttataat
     4081 gaaaattgtc aataatatat caaaaaaaat tttttaaaat ttatataatt aaatgaattt
     4141 atgtttatat atggatgata tgatatagat aattatcttt ataatacaat atagttctaa
     4201 aaaagaatat attagaagaa gagaatattt aaataaaaaa taccttataa agttaatttt
     4261 ttagtacttt ataaggtaaa tatatattgt attgtgggga caaatttaaa tcatttgata
     4321 ctaatcaaca ctaagaacta ataactctct atcatctgga gtaattgcat atattcttaa
     4381 tttcttgtat gtcataatat tttctccacc tgtaaaataa ctcctaagat tgacataatt
     4441 agttttaggt tgatttggat ctcctaaata attacgcatt tctttatctt tagttccaat
     4501 atctttaaat ccagaatatt gtaaagtagc ttcaactcta tatttttgga tataatcgag
     4561 agcttcttta ttagtttgtg ttggtgtaaa atacatacca tttatataag catttcctgt
     4621 acttggatta aaatttaaat ctgcagaata tattttatgt gcatctatta tttcttggtc
     4681 agttggaatt ttaacttctg gttcattaag tatttcagga gtactattca gttctgtaat
     4741 agataagtta tctaagtatg ttgtaccact accaattaat gttatctcta tattagaaga
     4801 atctttttca gtagtttcaa attcataact aaactttgta tatccttgtt ctggtaccaa
     4861 ataatccgtt ttttcttctt ttgcttttat ctttacaatt attgaattag atgttaaagg
     4921 atcctttgaa tatccactaa aaacataacg tttataaggt tttagcttag acataggtat
     4981 tttaatcttt gtctcaccat ttaatttatt tgctgagcct tgtaaaccat cttgattcgt
     5041 agtattgaca ttactccatg tactagggta attattgtaa tcatcaaaat tagtaaagta
     5101 agttggtgtt tttataagta tattcattcc tctttcaagt ttaacattat atatcttttt
     5161 atcagacaaa gtttttaaac tatctttaat cttattggct gtattatcat caaatatgag
     5221 ttcaacacaa ctttcatcta ttggtatatc attaaaatat aacaaaccat cttttttagt
     5281 agcgccaaaa gctttttcaa ttgcttctcc aattgtaagt tcaggtgttt tatcttctgg
     5341 attctgtaaa tttttagcag taactcttct ttcgtaagat tcattctctg tatctaatat
     5401 aatagatgca gaaatactgt caatttgact tatatagtct gaccaactat ttccttctgt
     5461 tactatttgt ccagaactat tttttgtacc aaaatttcca cttacttgtg ttgtttctaa
     5521 tttaatttgc tttccagcat ctaatttttt taattgatca taatttatag gaatcagtct
     5581 agagctaaat tgatccattg tgttaagagc cagaggtgaa agcccttttt tgggataagt
     5641 atctccagga gatagattat tgccaatttg attttcttgt gctttgatag ttgataatgt
     5701 atctccatct aacactaaat ttgttgttgg tgtcactttg tacataggtg cagtacctgt
     5761 gttgtaatat ctaacatttg catttatata tgcagattct cctttgttta tacttaatcc
     5821 agtattccat gattctccat tactatcttg aacggcagtt gaattatctg ttgtatggga
     5881 ataatttgta gttacattag ctgtgaatcc attttgatat cctacattaa cagaaacacc
     5941 agctgtatta gattcagttt tactgttagt agtagctctg gaaacagttt taccttgatc
     6001 agtagaggca tgttcatttg tagatataat taatttttcc atacctactc caacaattgg
     6061 atacgctgca actaacggat ctcttgcttc ggtctttata gccttgtcaa aagaacctga
     6121 agctttttca taatctgtat atggatctcc agcagtattt gactctaaat aatttgatac
     6181 atatttctta tagccttgtt ctgcaaagct atcttcccac ttaactgcaa ttaagtcctt
     6241 aatagtatat ccatttcgtt catatgaatc tggtatatta tcattatctg tatccaaatc
     6301 ttcgtcttcc caatcagaca tcaaccttgg gtcaaagaaa ttgttatttg ggataaatgg
     6361 atcatttttt tctatattag aataatctct taagaataaa ttttctgctg gtataatttt
     6421 cttaatacca tctaattccc aataaagatt aggtgatgac aaattatcta ttgaacctaa
     6481 atttttatct tgtagctcta ttctaaattt atattcttta ccctttttca tattaacttt
     6541 aagtgtattt gatatagtac tctcattatt tacttgcatt aaaatatcat ctctatcagt
     6601 tgataatgta tattcaccat ccttagaagg aattattctt cctgtccatc gtatagattt
     6661 tacatttgat ttgtctttat ttagaagttt atctactttc ttttcttcaa attttaaatt
     6721 accatctttt atgggtgcca ttaattttaa atctttaaag tgttcgtctg tgaaataata
     6781 tcccattaat ccgttgtttg tgagtatgtc ttcatttata atttcttttt tattatcaga
     6841 atggctactt gtactagttt gagcatatac aggatatgct aatgcttgac taactatggc
     6901 tgtaagtgtt aaaaaactta ataccttttt attcctcatt tgtactttca ttatttctcc
     6961 tcctttaatt tgaaatatat taaattattt atgtgaaaaa atattaaggt atcaatgttg
     7021 catcaacaat taattttgtt atagcgccat ctttgtaaga atcaatttta ctgattttaa
     7081 atttgcttcc atgatttaaa agtacttcat attcacctgc ataacctgga atagctgata
     7141 gataggctcc aggagaacct ttaggtatag ttatacgtag tactattttt cttttagcaa
     7201 atgcactcat attcacacta ccaatactag tactaataaa gtttggataa gacagtgttt
     7261 gtccttccca ttttgattta aaagcatcta tattttctgg tttgttaaaa tcatattcag
     7321 gggaagtaag ggttaaacca aattcttgag gaccagatct tctatataca gttaaattag
     7381 ttggaatagg ttcacgtttt aatgcatttt caatgtttgt gattttagaa tctaattctg
     7441 ggttagggtt atttactgga ccatttgata ttaaataatt attaattgca gtatatcctc
     7501 cacgcatata atcatttaca tcagcaagtt cattaggtgt taatttatta ctccaatcat
     7561 tataatttgc tttaccccaa gagtccccct tacttacatc atccttaaaa tcaagactac
     7621 ttacaacaga tgcttctgct ttaatataat gtttcccatc tataactata cgaacaattt
     7681 tatctatttt tatactatat ccttgctcta ttaatgtact tacattgtta gtatttgtat
     7741 atggtaacat accagtattt ctaggtaatt ttaagtgcat aagtaatggt gtaggttctt
     7801 catcaccttt tccaggttca tataaagaaa tttctttaaa tccatcttgc ttaaataatt
     7861 tgttttgtat agtttcttta aactcattaa atttttctaa tgaaatttcg ttttgatttt
     7921 ctgttcttat tactttatta aatgcaaatt tttctggaga ttcaaaataa tagacataca
     7981 taggtttatc tattttattt tttgatatag catttcgaag ttctctatat tctttttctc
     8041 gagaatttgc ttctatttga taatcataaa aataatttct tgtctgagaa tatttattta
     8101 tttctacaga atctttttta tatgattcta atgcttcttt ttcagatctt tcaagttttt
     8161 gctctattct ttctgcttct tttctttccc attctttagc cctttcttta tctttaagaa
     8221 aatcttctgg tctttctata ggagccttgt aagtagtatt gcaaactttt tcactatagc
     8281 tttgtaagtc ttgtgcataa atgttattag gtaacaaact acctaaagtt agatataata
     8341 tcaacaatat agatatacaa ttactaatac ttttatgttt tctaaatttt ttcatttatt
     8401 ctccctccca atattagttt aattaacttt tgaattttaa tttatttaga ttatataatc
     8461 taaataagaa ttttttatat aaatttcata aaatatgtag ctatatatca taaaaatatg
     8521 tatttatatg atatgtcagt acaaaataac aactgaatgt tttaaagaga ctatttcata
     8581 cctttatgat ttaatgagct atcttgttga atcataatct aggaacaatt gttacaatgt
     8641 ctaatagcaa ttgtatatga tatagtcagt atgtgttttt tcacaaaacg attatcatat
     8701 agaggattct taggaactac tttttttgta taaaaaaaga gatggttcaa atttttatct
     8761 tgagacatcc cctttttcta tttattatct tttaataatg ttctttaaaa tatttctata
     8821 tgtattagat atacgacata tatggccgtt actcatttta acattatttt tctttaggtc
     8881 gatagaaaca atatgatatt tattaactac aaaagattta tgtacacgaa caaagcatgc
     8941 atctaaatct gataaagact ttaaactttt atagaattca aatattctag aagtagtcac
     9001 taattttatt ttatgtggaa tagtgcttgt ttcaaaatat ataacttcat caaatgaaat
     9061 tttccatagt gaggaatctg agtagatagt aaaaaaatta gagcgataat ttttttcttt
     9121 aatgtatctt ttatgagcaa ttttaataca agcttttatc ttactttcag caatttccat
     9181 atcatgtttt agtataaagt ccataactta taacctataa tcgaagatcc ctaaaatcat
     9241 ttctatatga tttgtaagaa atatgattgg actaatataa tctgattctc taattttttg
     9301 tgctatccat aatccatcac ataattcatt acttatctta tattttgcgt ctacaactat
     9361 aaaatatatt cttactttat ttttttcagt aagctctttt aataacaaat ttgcattata
     9421 atataatctt acaacatcgt tatcaaaacc ttcttttatt aaaatattat ttatcttttc
     9481 ttttagtttt attccaaaac aaacatcatt atcaaaaatt aatatatcca ctaaataccc
     9541 tcctataaaa aattcaaaag taaaaaacta aaagtatttt atagaaaaat acgtaaaata
     9601 acactaggag ataaataaaa ttaaggatag ttagaattaa ggtatattta tgcttgttta
     9661 ta
//
LOCUS       DAMKOJ010000113         9563 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000113 DAMKOJ010000000
VERSION     DAMKOJ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9563
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.122"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            306..935
                     /locus_tag="PC592_003198"
     CDS             306..935
                     /locus_tag="PC592_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057134.1"
                     /translation="MNKYLLINPVAGRMYGEKFHLVKENLMKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESINLLKRNNLINSFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLIVTCPCTQLRDFASEKFKDKSNAIFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGSEDKYDIVEMFYCKDGCNNGDGL"
     gene            936..1718
                     /locus_tag="PC592_003199"
     CDS             936..1718
                     /locus_tag="PC592_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057135.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGIPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVDAYE"
     gene            1711..2589
                     /locus_tag="PC592_003200"
     CDS             1711..2589
                     /locus_tag="PC592_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057136.1"
                     /translation="MNNLVCDSGYIIRNLSKSYEVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLENINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     TFHNQRKNTILNKMLRKFKHNKRVIGKIINDNFRSLETNENLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLFMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDDYNRDLTSEYYI
                     KLKKDILMTMKSNKGI"
     gene            2622..3581
                     /locus_tag="PC592_003201"
     CDS             2622..3581
                     /locus_tag="PC592_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF4057137.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSIDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYV
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3895..4587
                     /locus_tag="PC592_003202"
     CDS             3895..4587
                     /locus_tag="PC592_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4057138.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSNIRRVYGEYSTKIDERIVELDGLKFYPERLELELHSKNLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     IRGLGYKLNKNW"
     gene            4597..5601
                     /locus_tag="PC592_003203"
     CDS             4597..5601
                     /locus_tag="PC592_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4057139.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVLTIIYCNLMKFISFDESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGIHSLEESVLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHGEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIREEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQIDKFTYVYTDV
                     KWMKFIIGQLVTNGVKYSKDCSNYITIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSISFNKDVNSLIKM
                     "
     gene            5837..6688
                     /locus_tag="PC592_003204"
     CDS             5837..6688
                     /locus_tag="PC592_003204"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF4057140.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVREFLKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSVMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAIYRIIMGAVLAVLA
                     LTNIISI"
     gene            6822..7568
                     /locus_tag="PC592_003205"
     CDS             6822..7568
                     /locus_tag="PC592_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057141.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKDKNLLLLKGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDRRLNEVSEILGIKDLLGKRTFEVSGGQAQRTAIARALINR
                     PSILLADEPTGNLDSKSSKTVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     AIYNEIYKGSSREQFYQDIMDVLTLLGGDN"
     gene            7568..9484
                     /locus_tag="PC592_003206"
     CDS             7568..9484
                     /locus_tag="PC592_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057142.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASITISSSLLFSFVMFTSHPDL
                     DLSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISNRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSLFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAVTST
                     DQYTTYLRLVPVTSLTIAATYLFFSQFSVFFIKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVKRQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMRFIENNLKKEDIDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITEVIG
                     VKPISFEDNESISLLSSSLPGNKKIKENVTVGNRSLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFDNESGMQPYLFFSKELMIET
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLLPYVVAVIHSIFALTALKNSFDLEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIKLNLVNY"
BASE COUNT         3729 a          897 c         1674 g         3263 t
ORIGIN      
        1 catagcattt ttaaaacttt ctacttttat tagttcgaat aactgttact attaaatatt
       61 aatactaatt atatacatat cattatataa tatttataga ttattatata agtagattat
      121 tagtaaaatg tatgcattat taattaaaat aaattacata tgttatttaa tattttattt
      181 aaaatattaa aaaatataga taaaaattgt tttattaaga aaaaattaat atattgacaa
      241 aatttaagtg ctcatttaaa ctattaattg ataataatat tcaatattaa ataataggag
      301 gagttatgaa taaatatctt ctaataaatc cagtagcagg aagaatgtat ggagaaaagt
      361 ttcaccttgt caaagaaaat ttgatgaaaa aagggtacat aatagcagaa tgtgaaccac
      421 aattagaata tgtaaaaaag cagtacaaag agtatacaaa aaagactgag aatacaatgt
      481 tggattgtag atgtccagaa agtataaatc ttttaaaaag aaataatttg ataaatagtt
      541 ttgaagtacc tatgatagaa ccaatattag taaggacttg tagggtttta tatgataaat
      601 atataaaaag taaagatgat atgctgatag taacctgtcc atgtacacaa ttaagagact
      661 ttgcaagtga aaaatttaag gataagagta atgctatatt ttatacatgg aaagagtttg
      721 ctgagcagga aggtgtaaaa tcgcttggaa aaatagatga atcaccaatt ccattaggat
      781 atttcaaaga tacttttgaa aaagtgcttg aagtatcaag tgaagatgaa atcttaagtg
      841 aaatacaaaa aataagaaat ggctctgaag ataagtatga catagtagaa atgttttatt
      901 gtaaagatgg ttgtaataat ggagatggtt tgtaaatggt caataaattt aataataaat
      961 ttttaaggct agtaaagagt gttctgatat tttttataat tcttttatta tggaaaatta
     1021 caaattatct tggtatttgg agtgattaca tactgccatc acctgaaaag gtatatagta
     1081 catttttaaa tatgataagt gatggttcga tatttattaa tgtatatgca agtatgaaaa
     1141 gagttttgat aggttttgca ataagtactg ctataggtat tcctttagga atattctttg
     1201 gaatttatag tggagtatac gaatatttta aatctctaat aaatttttta aggaatacac
     1261 ctccccttgc tttaatacca atgcttatct tatggtttgg tataggagag gaatcaaaaa
     1321 ttataattat agttttagca tcctttttcc caatctttac aagcacattg aagggtatta
     1381 aaaattgtga ctcaaaactg attgaagtgg gtagggtatt tgagttttca aagcttcaga
     1441 taatatttaa aataataata ccaaatgcca ttcttgatat tgcagttggg ctaaagttag
     1501 ctcttggata tagttttaga gcaattattg gggcagaact tgtagcagcc tcatctggtc
     1561 ttggatactt gatatctgat ggaaaagaaa tgtctagaac agatgttgtt attgtaggta
     1621 taatcgtaat tggactttta ggaataatta cagattacat attttcgatt attgtgaaga
     1681 aggtaagtaa gggaaagatg gtggatgcat atgaataatt tagtatgtga ttctgggtat
     1741 ataattagaa atttatctaa aagttatgaa gttgacaatg aagaacatgt agttcttagt
     1801 gatatctctt taaacataga tagaaaccat ataacagtaa ttttaggtga aagtggttgt
     1861 ggaaagacta ccttgcttag agcaattgca tcacttgaaa atataaatag tggtgaaatt
     1921 aggtttatta atgataataa agagtataga cctaatgttg gttttgtctt tcaggagagt
     1981 cgattgatgc cttggctaaa cgtaagtgaa aatattactt ttcataatca aagaaaaaac
     2041 actattttaa acaagatgct tagaaaattt aaacacaata aaagagttat tggtaaaatt
     2101 ataaatgata attttagaag tttagaaaca aatgagaatt tgaacaaatc aaataaatat
     2161 aataggaaaa gtaatattga tgtagaaaaa tatcttaaga tgatgaactt gcagaaattt
     2221 aaaaactctt atccaaatga attgtcagga ggtatggcac agagagtaag tatagctaga
     2281 gctctttctt tcaatccaga tatgttgttt atggacgagc ctttttcggc attagattat
     2341 tttacaagga ttgatatgca aaatgaagtt ataagaatac ataagtcaac taataaaggc
     2401 gtaatatttg taactcatga tattgatgaa gcattaaaga taggcaagaa aatagttgtt
     2461 tttacagatg aaagaaaaat aaaagaattt aatatagaag atgattataa tagagattta
     2521 acttcagagt actatattaa attaaaaaaa gatattttaa tgacaatgaa atcaaataaa
     2581 ggcatttaaa gaaattaata atattttaag gagtagagta aatgaaatta aaaaagctat
     2641 tgataggtat aacaatatta acgcttgcaa cagcatcttt agctggatgt gctaaaaaaa
     2701 ataatggaga aaaactttca gaaataaatt taacttatgt aaaatcacca ttaaatgttc
     2761 cttctataat tcaaaaacag gatgatttat ttggaaagga atttaaaaag gataatataa
     2821 aagttaactt ccacgaaatt actacaggtc cagagcaaac acaagcttta gctgctggag
     2881 aaatagactt tttacatgca ctaggtggta cgtcagcttt aatagctgca tctaatggag
     2941 tagagttaaa gatattaaac acttatagca ggtcaccaaa aggatttatg attttgacta
     3001 ataataattc aataaaatca gcagcagatt tagtaggtaa gaaggtggca gggccaaaag
     3061 ggactatatt acatcaggta ttgatttcag cacttgataa agaaggatta agtatggatg
     3121 atgtggaatt tgttaatatg ggtattccag aggcatcagc agctctttct gatgggagta
     3181 tagatgctgc attgattgct ggtccagcag ctcttaaagc tatgaagtca gggagtaaac
     3241 ttgtagcaaa tggtgaaggt ttagtagatg gcataatagt aactgctgtt agcacagact
     3301 ttgcagagaa acatccagaa atagttgaaa gatttatgaa ggttgaaaag gaaactttag
     3361 aatatgtaaa taataatttt gatgaagcta tggaaaaagt agctaaagaa gttgatttaa
     3421 gtcttgaaga aactaaagaa ttatatgttt ggtatgattt tagtttagat ataacagata
     3481 aagacatatc ttcacttgaa gatacacaag acttcttaat aaaaaataag ttacaagaga
     3541 aaaaagtgaa cataaaagaa ttaatatata atgctaagta gaaactatgc taaaataata
     3601 ctaagtaaga aatataataa aagtttaagt taccttatta aggtaacttt ttctattttg
     3661 aattagtaat ttaaatttat tttagaatga ttaattgata atagtgatta attaatcata
     3721 aaaagatacc tttttataga gttttgttaa gatgtctaat aatatagttg tatctatgaa
     3781 gtcagtaatt gtgaagttag taatatgatt aaatttatat attgtaaaaa tatcataata
     3841 tattaaaatt gagctgttat atgatgagta aaaaggtata ttaggaggaa ttatatgagt
     3901 tataaagtat atattgtgga agatgatata tcaataagta cattacttaa agattatatt
     3961 gagaaatatg gatttgaagt gattgttgaa gaaaactttg atgatataat gattacattt
     4021 gaaagcttta agccacactt agttctgtta gatgtaaact tacctaaatt tgatggtttc
     4081 tactggtgta ggtgtattag gcaacagtcg aatttgccta taatttttat atcagctaga
     4141 gatggtaatg tagaccaaat tagagcttta gaaagtggag cagatgatta tataacgaag
     4201 cctttttact atgatgtagt aatggcaaag ataaagagta atataagaag ggtatatggt
     4261 gaatattcaa ctaaaataga tgaaagaata gtggagttag atggattaaa gttttatcca
     4321 gaaaggttgg aactagaatt acatagtaag aatctaatta taaccaaaaa agaaggtata
     4381 ttgattgaat gtcttatcaa aagataccca aaggtagtaa gtagagatta tcttttagaa
     4441 aagatatggg atgatattga gtttgtagaa gaaaatactt taaatgtaaa tgttagtagg
     4501 ataaggaaaa gatttgagga attaggcata gataatgctg ttcagactat acgaggatta
     4561 ggatataaat taaataaaaa ttggtaagga gaaagtatga agttattttt aaaagattat
     4621 aaaggttata tttttatata ttatataggc atagttctga caattattta ctgtaatctt
     4681 atgaagttta ttagttttga tgagagttta tatattcttt tatttagttc ttttatattg
     4741 ttatgttttt taatatataa gtactataaa aatagagaag tatataatct gtttgaaaaa
     4801 ggaatacatt ctttggagga gtcagttttg tatttaggaa gctctttctt ggggagaaat
     4861 atatcagtta ttttaaaaca acaacataaa ttgtatcaat caatgataca agagcataaa
     4921 aagatacatg gtgagcattt aactttcatt aatcaatgga ttcatcagat gaaaacgcca
     4981 atatcagtta taagccttca gcttcaagat tatgagggag aagaagtaac tgaaaatata
     5041 agagaagaaa tagatagatt aaataaaggg ttagatatgg ccatgcattt tgcaagggca
     5101 gataattttc agaaagactt tatagttgaa aaagccaaat taaatgaaat tgtatctagt
     5161 attgtaaatg aagaaaaaag gttatttata aaaagtggaa tgattcctaa gattcaaata
     5221 gacaagttta cttatgttta tacagatgta aaatggatga aatttataat aggtcaatta
     5281 gttacaaatg gggtgaaata ttctaaagat tgtagcaact acataactat aaaatctgaa
     5341 gaaaataata agtatgtaat tttaagtata atagatgaag gaattggaat tgtttctaaa
     5401 gatttaaaaa gggtatttga cccatttttt acaggagaaa atggtcgtaa gtttggagaa
     5461 tctacaggta tgggtcttta tctagtaaaa aaggtatgtg atgatttagg tcataaagta
     5521 agtataaaat cagaagtagg aaaaggtaca gaagtttcaa tctcctttaa taaagatgta
     5581 aatagtttga taaagatgta aattatctgt tacaataggg tttttagtta attgtacttt
     5641 tttattaaat gaaatattca tagttaaata atccaaattt aaaagaattt atttgcaaac
     5701 cttacataga tgtaaggttt gtgtaatgtt tgcagatagt taaattttct aatctaaatt
     5761 acaattaata taagaaataa cataagggaa ataacataaa aaaagaaatt ttgtaaaaaa
     5821 ggaaggatat ttattgatga gtttagatgt tatttttata ttgaaatcag tcataatagc
     5881 tatagtagag gggcttacag aatttattcc agtttcatct acaggtcata tgattttggt
     5941 tggtaattta atagatttta aggggcaatt tgctgaaatg tttgaggttg taatacaact
     6001 tggagccata ttagcagtag tagtactcta ctggaaaaag ataaaagata gtgttagaga
     6061 atttttaaaa tttatattta ctggcggaaa agaaggaaag attggtttta gatttggaat
     6121 gaatgtaatt ataggttgta taccatttgc gattatagga gttctatttt acgataatat
     6181 aaaatcattg tttaatttac aatctgtaat tataggattt atagtgggtg ggattttatt
     6241 attagtagta gaaactttgt ttagaaaaaa gaatcattcc acagataata tagataaaat
     6301 tactccaata caagctttaa aggttgggac attacaagtt ttgtctgcat ggcctggtat
     6361 gtcaagaagt gcatctacta ttatgggtgg atggatagca gggcttaatt ctcctacagc
     6421 agcagaattt tctttctttt tagctgtacc agctatggtg gcatcttcag gaaaagattt
     6481 atttgaattt gattattcag taatgacacc aacattgtgg attgctttgg tagttggatt
     6541 tatagtagct tttattgtat caataatagt tatggaaaaa ttcgtgaatt ttttaaagaa
     6601 aaaaccaatg agagtgtttg ctatatacag aataatcatg ggtgcagtac ttgcagtatt
     6661 agctttgact aacataatta gtatatagaa aaaatagatt tattatctat agaaattaaa
     6721 ctaagagaaa ttataattaa caattatata tatgttattt caaaaattaa attaggaagg
     6781 tatgttattt caaaaattaa attaggaagg atagttaaat aatgaaaatt ttaactgtaa
     6841 ataatttaag taaagtatat ggtaaaaaaa taattttcaa tgcattaaat gacataaatt
     6901 ttagtataga agatggagaa tttgtaggaa ttatggggcc atctggcagt ggaaaaacta
     6961 ctcttttaaa tatgatttct actattgaca agccaactac aggaactatg gagctaaagg
     7021 acaagaatct tttattgtta aaaggtgaag aacttgcatt atttagaaga agagaattag
     7081 gttttgtatt tcaggatttt aatttattgg atacattaac tataggagag aatatagtat
     7141 tgccattgac attagataag gtcagtgtaa aagagcaaga taggagattg aatgaagtat
     7201 ctgaaatttt aggaataaaa gatttattgg gaaaaagaac ttttgaagtt tcaggtggtc
     7261 aagcccagag aactgccatt gctagagcat taattaatag accatctata cttttagcag
     7321 atgaaccaac aggtaattta gattcaaagt cgtcaaagac tgtaatggag ctatttcaaa
     7381 agataaataa agaaaataaa gttactacta tgatggtaac tcatgaccca ttagcagcaa
     7441 gttattgtag tagaatttta ttcataaaag atggagctat atacaatgaa atatataagg
     7501 ggagtagtag agagcagttt tatcaagata taatggatgt acttacatta ttgggaggag
     7561 ataattaatg aacataaaac agtttgctat taataatatt tcaagaaata tcaaagcgta
     7621 tttaggatat ttagcaagta ttactatatc atcttctcta ctattttctt ttgttatgtt
     7681 tacgagtcat ccagatttag atttatctca atttcctgat tatttaaaag aaggtctcaa
     7741 gatgagtaag ataattgcat atttattttt attcttcttt gtattttatt cagttagtgt
     7801 atttcttaaa agtaggtata aagaatttgg tatactttat attacaggta tatcaaaccg
     7861 acaagtaatg aaattaatct ttatagaaaa tatgataata aatatagtat cttctgtaat
     7921 tggaataata ataggcttaa tctttgcaaa gatattttta gtggtgatgt ctaccttttt
     7981 agaattatca ccattaaaat tctatatacc atttaatgcg atattgtcta ctttaatcta
     8041 ttttatgatt ttagctgtat taacatcact atttacttct tttatagtta aagaaaatca
     8101 ggtgttgaag ttacttaaag gtacaaaaac tccaaaacca gagcctaaaa catcactaat
     8161 gcttgctata ttaagtattt gtttgtttat aatagcgtat tataatgctg ttacatcaac
     8221 tgaccaatat acaacatacc tgcgcttagt tccagttaca tctcttacta tagcagctac
     8281 ctacttattt ttttctcaat ttagtgtgtt ttttataaag aaactaaaat taaacaagag
     8341 attttataga aaaaatacaa atatgctttg gatttcaaat ttaatttata aggtaaagga
     8401 taatgctaga atatttttct tgataactat aacctctgca gtagcattta ctgctatagg
     8461 tacagtttat tcattttgga aagatgtaaa gcgtcaaatt aatttaatat atcctaatac
     8521 aatatattat tcaacaatga ccttgcataa tgaccctaaa aagcctgata gcaaagaaaa
     8581 agacaaggaa agaatgagat ttatagaaaa taatctaaaa aaagaggata tagactatac
     8641 aagaattaat ggcgagttta aaactgtatt tcccaagaaa agtgatttta atgtcagaat
     8701 tatgaaagaa tctaagtact tagaaataac agaagttata ggggttaagc ctataagttt
     8761 tgaagataat gaatctatat cattattatc atcaagttta ccaggaaata agaaaataaa
     8821 agaaaatgtt actgtaggaa atagaagctt aaaggtggca aaacaagtag aagaatgtgt
     8881 tatgccagca tattataaaa atatgtatgt ggtaaaggac aatttttatg atagtataga
     8941 atcaaaattt atagtggata gatttactgc atttgaagta gaggattcaa gtaaaactat
     9001 agagatatgc agagaatttg aaaataaatt tgataatgag tcgggaatgc aaccatattt
     9061 gtttttctct aaagaattaa tgatagaaac tggtaaatta atgtattcta catttatatt
     9121 tttagcaata tttataggtt taattttctt cgttactaca agtagcttct tatacaacaa
     9181 gttttatatg gattgccaag ttgacaagaa aaagtatgaa cagttaaata aattagggat
     9241 gacatataat gagattaaaa aagcttcaac tattgagatt ggcatagtat ttttgttgcc
     9301 ttatgtagtg gctgttatac attcgatatt tgcacttact gctctgaaaa attcttttga
     9361 tttagaagta gcatcatcag ctgttttggt aatgggaagc ttgttcttgg ttcaaatagt
     9421 ttatttttta attgtaagaa ataattattt gaaagagata aaattaaatt tagttaatta
     9481 ttagttacta ttattaaatg ataacaaaaa gggtttaaaa ttaattaata ttactggaat
     9541 tatagatgtt tattttttca gta
//
LOCUS       DAMKOJ010000114         9517 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000114 DAMKOJ010000000
VERSION     DAMKOJ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9517
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.123"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(137..790)
                     /locus_tag="PC592_003207"
     CDS             complement(137..790)
                     /locus_tag="PC592_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4057143.1"
                     /translation="MEERLMKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIG
                     VSRTPAREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQN
                     LTESDLVKMEELIEMMAVSIKYKNYSSYLKLSNEFHDIYITKSNNQVLVNLLNSLRYN
                     FMSKSYTSDNEDELYKMLTYSNNQHIEVVKFMRENDLENIERVLREHWKTIPIAEMK"
     gene            complement(1021..2886)
                     /locus_tag="PC592_003208"
     CDS             complement(1021..2886)
                     /locus_tag="PC592_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HDF4057144.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELNICVKVNEGYNVKSIFL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDIPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELINKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDK
                     DSVINKWINMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFKSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYKDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRILILVN
                     RSENVESISLCMDSSFIEEIPIKYSLKNVNSTIQIENNELKVDLESKSFRIFRVN"
     gene            complement(2891..5311)
                     /locus_tag="PC592_003209"
     CDS             complement(2891..5311)
                     /locus_tag="PC592_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HDF4057145.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLDIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFINGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRVKRMSIIDYDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKRDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNIDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5325..6767)
                     /gene="glgA"
                     /locus_tag="PC592_003210"
     CDS             complement(5325..6767)
                     /gene="glgA"
                     /locus_tag="PC592_003210"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDF4057146.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTNAVLESISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQTYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDASIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6796..7926)
                     /gene="glgD"
                     /locus_tag="PC592_003211"
     CDS             complement(6796..7926)
                     /gene="glgD"
                     /locus_tag="PC592_003211"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HDF4057147.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7928..9088)
                     /locus_tag="PC592_003212"
     CDS             complement(7928..9088)
                     /locus_tag="PC592_003212"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDF4057148.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         3007 a         1749 c          923 g         3838 t
ORIGIN      
        1 atatactaca tattgtagtg tcttagagct tttatttgta ttttaaatta aatttattct
       61 tgtttttcct ttaataatta atagtaaaac aaaaaaaata taaaaaaaat aaagagaaac
      121 tttataaaag cttctcttat ttcatctctg ctataggtat cgttttccaa tgttctctca
      181 aaactctttc aatattttct aagtcattct ctctcataaa ttttactact tcaatatgtt
      241 gattattgct gtatgtcaac attttatata actcatcttc attatcacta gtatatgact
      301 ttgacataaa attgtatctt aaagagttca atagatttac taacacctga ttatttgatt
      361 tagttatgta tatatcgtga aattcattgc ttaattttaa atagctactg taatttttat
      421 actttataga gaccgccatc atttctatta attcttccat tttcactagg tctgattcag
      481 ttaaattttg taatgctgaa gaaccggcta acgcatccaa tactccaatt acagaatagg
      541 tgtctaattt ctccttttct tgaaattctt ttactacaaa tcccttatta ggtatttttt
      601 ctagtaaatt ttcacctgct aacctagtta atgcttctct cgctggtgtt ctactaactc
      661 cgatagattt acaaatctca gattcagtaa ttctctgatt agcttcatac tctccatttt
      721 ggattttctt tgatatatag tcatatactt gagttgtaag tggatctacc ttcataagac
      781 gttcctccat attaagatta taaaagttaa atctccctac aactttggta gagagttcag
      841 ttttatctta ctaatttata taatatcaca attatgatat tttttatact tctttgtaat
      901 attttgaaat actaaaattc ttatgataat ttatacaaaa aaatgtagaa aaagttttga
      961 taaaacaaaa ctctttccac attcccctta ttttctattt atttttctaa acaaatatat
     1021 ttaatttact ctaaaaattc taaatgattt agactctaaa tccactttca actcattatt
     1081 ttcaatttgt atagtactat ttacattttt aagactatac tttataggta tttcctcaat
     1141 aaaactacta tccatacata atgatatact ttccacattt tcacttctat ttactaaaat
     1201 taatattcta tcattatttt cattaactct aataaaggaa aatacagaat cattattagt
     1261 atatataaat tctgtatttc cagaacttaa aagtttattc ttatttctaa tttttataac
     1321 atctttataa aaattaagca tatcttcatc ttcatttttc catggatatg ttcttctatt
     1381 atctgggtca acacctccac aaagacctgc ttcatctcca tagtatatat atggtactcc
     1441 ttcaaatgtc atctgtatag ctacagcaag cttcactaaa tctacatcat catttaattc
     1501 tgttttagct cttgtaacat catgtgttcc aattaaattt aaattagact taaatgattc
     1561 ctttggataa ttttctttaa tctgcatata tctattacaa agttcgtatg aattaatttc
     1621 tccttttaag aaagaaaaca tgttatttct aaaaggataa cccataacag aatctaattc
     1681 ttcacctaat aaataacttc ttctctgacc atagctaatc ttatttgatg catcttccca
     1741 tacttcacct ataagaattg agtcatcatc cgcctttttt aattcctttt ttagttctct
     1801 tataaactta gttggtagtt cgtctgcaac atctagtctc cagcccttaa tacccatatt
     1861 tatccattta tttataacgc tatccttatc atatattata taatccatgt agctatgttc
     1921 taattcattt atatttggca atgtcttaac atcccaccaa cttttatact tttggggaaa
     1981 ttcttcaaac atataccatg aataatatgg agattctttt gattgatatg ctcctaaact
     2041 attatagttt ccatacatat taaaatattt actatctgct ccagtatgac taaaaactcc
     2101 atctaatact attgatatac ctttttcttt tgctttatta ataagttctt taaatgtatc
     2161 ttcatcccca aacattgggt caattttttt ataatcacct gtgtcatact tatgattact
     2221 agaagcttca aatatagggc ttagatatag tatacttaca cctaattttt ttaaatatcc
     2281 aagtttattg attatccctc ttaaatttcc accatggaaa tcccacctta taacatcccc
     2341 ttgactatcc tttatgtaca taggtatatc ttcccaattt ccatatatga aactattttt
     2401 tttaggatta tcaaccttac cactacgatt cccattatta aatctatcta caaatatatg
     2461 ataaagtatt ccttctttgt accacgttgg tactttaaaa tctttgtaaa cagtgatttg
     2521 atatttatta atatcactat aattatattc acaagagtat ccgttatctc tgttttttcc
     2581 ataaaataaa gtctttatct gaccatccat ttcaacatca actttaaagt aataaaaata
     2641 aacacctgtc ccatcaaact tttcaatctt accacaaaag cactttccaa gtttatcatt
     2701 atctaattct tcatttaaag ttattgttct catttcttct tctctattta tttctaggaa
     2761 aatagacttg acattgtatc cctcatttac tttaacacaa atgttcaatt cctcatcaaa
     2821 ttttaaagct ccaaacggag ccttaaaatt tttatcccaa gaattatatt ctattacact
     2881 ttgcatttaa tcacaccctt ttaaaccaaa tgtcttttgc atactcagaa attgttctat
     2941 cagaagaaaa aaatccagag ttagctatgt taactaaaga cattttattc catttttctt
     3001 tatctctata taacctgttt atatctgctt gagcttgacc ataattttca aaatctctca
     3061 atacaaaata ctcatcattg taagtagtga gtgagttata aatacttctt ccttcttcgc
     3121 caagattagg aataaatcca tttattaaat catctactac cctttttata tccatattag
     3181 aatgatatag gtcaagtgaa gaatatccac catatttatt ataatttagt acttgttctg
     3241 cactaagtcc aaataaaaac atattttctt taccaacctg ttcacatatc tctacatttg
     3301 caccatcaag tgtagccaaa gttatagcac cattcatcat aaacttcata ttacttgttc
     3361 cagatgcttc ctttgttgta gttgaaattt gctcactaac atttgctgct ggtattatta
     3421 tttctgctaa tgatactcca taattctcta aaaatactac ttttaacttg tcctttactc
     3481 taacatcatt atttatagta cttgcaacag aatttataaa tttaattata catttagcca
     3541 aataatatcc tggtgctgct tttgcaccaa atataaaagt tcttgggtca agatttaaat
     3601 taggattatc aagcaattca tgatacatat gaagtacatt aaatatattc agtaactgtc
     3661 ttttatatgc atgcaatctc ttaacttgaa catcaaatat tgaacttggg tctatattta
     3721 aatcgtattt atcttttata aactttgcta gatttgcttt attattgtat tttatatcat
     3781 caagtctttg taagacagaa gaatcatttt taaatttttc aatatttttt aattgtaagg
     3841 tatccctctt ccatgaatca ccaattaaat ctgtaattaa attgctaagt tgaggatttg
     3901 aacttataag ccatcgtcta tgtgcaattc cattagtctt attattaaat ttatttggtt
     3961 catcttggta gaaatctttt aatacctctg tttcaagaat atgagtatga agcttagcaa
     4021 ctccatttac actatgactt gtcacaatac ataaatttgc catattgata ttgtcatagt
     4081 ctattatact cattcttttt actctatctt ggtcatatcc tttattattt aattcctcta
     4141 catatcttct atttatttct tctattatca tataaattct tggtaatagt tctttcatca
     4201 tacttacagg ccatttttcc attgcttctg acattatagt atgattagta taagacactg
     4261 tttttttagt tatttcccat gcttcatccc aagataaatt ttcttcatca agcaaaattc
     4321 tcataagttc tggtatgcat aaggtaggat gtgtatcatt tatatgaatt gctaccttat
     4381 cgaataaatt attgatattt aatttgttct ttttatattt tcttattata tcttgtatcc
     4441 ctgcacttac aaaaaagtat tcttgtttca acctcaacaa cttacctgca taatttgaat
     4501 catcaggata taacacctgt gatatttcct cagtatagta cttatgtttt aaagcctctt
     4561 catagctacc agagtaattt agagcatttg aggtaagctc accaaaatct ctctttggta
     4621 tttcactctt aaacaatctt aaagtattta tacattggtt ttggtatccg attattggta
     4681 tatcataagg cattgccatt acaggaaggt agtttttatg aattactttt aaatgactac
     4741 cttccttgat taattctacc tcaccaccaa acttcaccat tgttgcttca tttggtctta
     4801 cagtttccca tgcatatcgt ccttctgtaa gccagttatc aggcacttct acctgataac
     4861 catttataaa tttttgttca aacagaccgt atttatatct tattccatat ccttgaccac
     4921 ttatgttcaa agacgccata gaatctaaaa agcaagctgc taatctacca agcccaccat
     4981 ttcctaaggc tgggtctact tcagcttcta ttaaatcatc caagttgatt cctaactctg
     5041 acaaaccttc tctaacttct tcttcaatat ctaaatttaa taaattagat tttaattgtc
     5101 tccctattaa aaattctaaa ctaaaataat aaacctcttt tttcttgtct aactttgtag
     5161 caacccattt ttttgctatt tcatctttca atagactaca taatacattt aacaattgtt
     5221 catcagtagc ttccttgata gattgtgcat ataagctata catttttact tcaaattttt
     5281 gcttgaattt ctttttgctt attgttacca aaaaaaccac tcctttaatc acatatgtct
     5341 ctatatgttt ctatatactc cttagctgat tttttccaac tattatctgt tttcattgca
     5401 ttttcaacta atttaatcca tttttctttg tccttaaaca ctttgattgc atttttcaaa
     5461 cagaaaaaca tctcatgagc attgtaattt ttaaaactaa atccattgcc ttctccagta
     5521 aatttattat aaggtgttac tgtatcccta agccctccag tctccctaac tattggtaaa
     5581 gaaccatatc tcatagctaa catttgacct ataccacaag gctcaaataa tgatggcatt
     5641 aagaacatat cacttgcagc atatatctgt tgagccaatg atgcattgaa agtaattcta
     5701 gctgatactt tatctgaaaa attagaatcg taatagttga acattgattg atattgatgt
     5761 tctccagttc ctaaaacgac aatctgtaaa tcttctctca taagttctgg catcatgtat
     5821 gctattaaat caaatccttt ttgagaaact aatctcgaaa ctatacctat caacggaata
     5881 gatgcatctt ttttaagtcc caatatatct tgtaatctca atttattttc tacttttttg
     5941 tcaattgagt ctacatcata atgaacaaat atatctttat cttttgcagg gtcatttaag
     6001 tcataatcta taccatttaa tatacctttt aattttcctg actcttttct aagtaatcca
     6061 tctaattgtt caccataaaa agatgtttgt atttcatttg cataagtagg actaacagtt
     6121 ataattttat ctgcaaaatt tataccagct ttcataaaat ttattgagcc ataatactct
     6181 atatctccat tatcaaagta tgtttgtggt aagtccaata tatcatataa aacatgctta
     6241 tcaaatacac cttgatattg gagattatgt atagtataca tagtttttat atttttatac
     6301 ccctcaaggg ttgcatatct ttcttttaga attaatggta acatccctgt atgccaatca
     6361 tttatatgta ttacatctgg ataaaaatca attctactta tagattctaa aactgcattt
     6421 gtaaagaaag tatatctttc tgcatcatct ccatatccat agatgctctt tctttcatct
     6481 tctcttctaa aataaaactc attatctata aagtaaaatt ttacaccatc aagttccatt
     6541 tccaaaagac cacagtattg atttctccat ccaacacgta cactaaacac agctatttct
     6601 tttagttgat cttttaaata acttggtata gttgaatatt tgggcattat tacccttaca
     6661 tctacacctt ctttttttaa ttctttaggc aatgcataag aaacatctcc taatcctcca
     6721 gtttttgcaa agggccaaca ctctgctgtt acataaaaaa ctttcattag tcattccccc
     6781 ttctaaaaaa tttatttata tatttgtatt cttttccact acaagaggat atttttcatc
     6841 tcctcttaat tctttcccat ttgatacact cgtattttta tctaatattg cattatataa
     6901 ttttgcattt gactttatta cacaattttg cattactatt gagttctcta taactgttcc
     6961 tttttcaaca tttacctttc taaatatgat actatctttt acagtccctt caattaaaca
     7021 accagatgct ataaagctgt tttctacttt agcactatct gtataaattg taggtgattc
     7081 attcttttct tttgtaaata tctttctttc agaatataat aattcatcag caacttctaa
     7141 atttaataaa tctttgctca tttcaaaata tgattcaaca gaatttacac attttagata
     7201 tcctgtatat tcataagctc ctattttcat gttttctgct tcttcaataa taaattcttc
     7261 taaataacaa taattgcctt tatttacaat gttatatata cattcaacaa aatcttcacg
     7321 tttcataata tacgtttcca tacatatatt tgctctaggg aatttaccca aattatttcc
     7381 tacatttatc actctattgt tactatctaa atttagagtt aagttaccag caaaatcttt
     7441 atttgcatta tttacatttt tatatattat agttatatca ttatgagatt ttttgtggta
     7501 ttccaatgct tgagaataat ttaaattaca tagcatatag cttggagcta ttaaaatata
     7561 ttcttcttca ctcttttcta tataatctag attagctaag atagtatata tatcaccttc
     7621 tctatgtgag taagtatttc tatacttagt gttttctgga ctaaaaattg ataggccacc
     7681 tttctttcta cttaaatccc aatctttacc actacctata tggtctgtca atgatctgta
     7741 tttttccttt gcgaatattc caaccttagt gattcctgaa tttatcatat tagataaagc
     7801 gaagtctatt attctatatc ttccagctat tggtgtagat gctattggtc ttccatagtt
     7861 aagtttgttt attgctgggt ctcctttttt gtttaaattt attatcccta aacattcatt
     7921 tctcatctta aagacctcct tctattaata cgcatctagg ttctatattt tcatactcag
     7981 aaactacatt tatttcatta tttacattct ttatctgaac attatcattt atagttgcac
     8041 actcacctat catagctttt tctatagtta cattttcacc tattacaaca tttggcatta
     8101 ttactgagtc aattacttta cttcctttac caacaacaac tccatgtgat agtacagaat
     8161 tacctacttc acctaaaatt ctacaaccat cagctatcat tgatctatga acatttgcat
     8221 ttttacctat atattgtgga ggcattgcca tagtatttgt atatatcttc catttagggt
     8281 ctgctaaatc aagtgtttct ggagatttta ttatatccat attagcatcc cataagcttt
     8341 gtatagttcc tacatctctc cagtatcctt taaatggata ggcatacatt ccaacattat
     8401 cttctaacat tttaggtatt aaattttttc caaaatcatc ataatttatt tccggatttt
     8461 tttctgcttc cttaaaataa tttctcaaca ttttccaatc aaatatgtat actcccatag
     8521 atgccaaatt actcttaggt tcacttggtt tttcttcaaa ttcatagata cttgaatctt
     8581 catttgtatt cattatccca aatcttgaag cttcatccca aggaacttca attactgcta
     8641 ttgtagcttt agatcctttt tccttatgaa attttaacat tttactataa tccatcttat
     8701 atatgtggtc accagataat atcaatacat attctggatt ataggtatct acaaagtcca
     8761 tattttgata tatcgcatgt gctgtaccat tataccaatt tccttctttt tcattcataa
     8821 atggttgtaa aacatagacc ccaccattta ttctgtctaa atcccaatga cttcccatac
     8881 ctatatgtga atttaatatc aacggtctat attgagttaa aacacctaca gtatcaatac
     8941 cagagtttga acaattactt agcacaaaat ctataattct atacttacct ccaaatgata
     9001 cagctggttt agcaattctt tttgtaaaga cgcctaatct tgaaccttgc cctcctgcca
     9061 aaatcatagc taacatctct tttttcattt aatgacactc ccctcatcta gtaattagta
     9121 tttataattg catttttact tttataaact ttatcagtca ataaatgttg tgtataaatg
     9181 ttgcttaaat aataccttaa taaaaataaa ataatatcaa ctatacaatt gatacaatgt
     9241 ataccccata atgcacttgc cgacgtatac attattttcc ataatcacta tagtattaat
     9301 taatattcaa ttatcagtta aaaaataata caaattttat tttataaata taaaaacatt
     9361 ttttataaat ctcttgtgcc atacaaacat acttgttttt taatttgtta aattcataat
     9421 agcaaaatac aatctaacac ttgttaaata attatccaaa taaaatcaag taattattaa
     9481 tcaattttat ttttaattga tacttctttg tctatca
//
LOCUS       DAMKOJ010000115         9516 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.124, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000115 DAMKOJ010000000
VERSION     DAMKOJ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9516
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.124"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            87..1847
                     /locus_tag="PC592_003213"
     CDS             87..1847
                     /locus_tag="PC592_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF4057149.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSGQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISERVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKEVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKINVSKI"
     gene            2276..4156
                     /gene="prdA"
                     /locus_tag="PC592_003214"
     CDS             2276..4156
                     /gene="prdA"
                     /locus_tag="PC592_003214"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF4057150.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            4237..4521
                     /locus_tag="PC592_003215"
     CDS             4237..4521
                     /locus_tag="PC592_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057151.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            4559..5284
                     /gene="prdB"
                     /locus_tag="PC592_003216"
     CDS             4559..5284
                     /gene="prdB"
                     /locus_tag="PC592_003216"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5009..5011,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF4057152.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            5364..6122
                     /gene="prdD"
                     /locus_tag="PC592_003217"
     CDS             5364..6122
                     /gene="prdD"
                     /locus_tag="PC592_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF4057153.1"
                     /translation="MEEKIIRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKEQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            6137..6604
                     /locus_tag="PC592_003218"
     CDS             6137..6604
                     /locus_tag="PC592_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF4057154.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            6621..7103
                     /locus_tag="PC592_003219"
     CDS             6621..7103
                     /locus_tag="PC592_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF4057155.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GVDGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            7123..8130
                     /locus_tag="PC592_003220"
     CDS             7123..8130
                     /locus_tag="PC592_003220"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF4057156.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            8250..9131
                     /locus_tag="PC592_003221"
     CDS             8250..9131
                     /locus_tag="PC592_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF4057157.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWVNVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT         3741 a         1161 c         1881 g         2733 t
ORIGIN      
        1 ttatttaata aataattatt ataatatgct agaataaata tatataaata agttttgatg
       61 atgtactatt ataaaggggg gactttatgt tttcgatacc agaagtaaaa aaagtagaag
      121 aggtaatgga tacaaaattt acaactatag acgaagacac aagaattgaa gatgcaataa
      181 aagaaatgat aaaaagtaat acaaaaactc taatggtaat agattcatct ggtcaattaa
      241 aaggcattat atccatgacg gatatacaca atctttatga gatgcataaa aagtatgaag
      301 gccaaccagt aaaacttata atgaagaagg atgtaatata tgtcaatgaa ggtttaacct
      361 tagatgaatg tagagatata atgatattaa aaaatatagg gattcttcct gttcttagag
      421 ataataaaat tattggagtt ctaaaacaag agcatattag agactattta tatatgcatt
      481 tagaagatta tggattgact ttgaagtata ttataggtca aattaaagag ggaatttgtg
      541 ctataaataa tgaaggtgtt gttatcttgt ggaataagtt tatggaagaa aggtatgata
      601 taaagtctga agacatagtt ggtcgaccga tgaatgagtt tttggaaaat actatttcag
      661 aaagagtgct aaatagtaaa gttggaatga gtgacctgta ttttacggat aaaaaagaaa
      721 atatgtatgc attagtccat gcaaatccta tattttataa agaagaattt atcggtgttg
      781 tatgtacaga agttgatgtt acagaagcta agatattagc ccttgaactt gaaaaagtaa
      841 atgatacatt gaaatatcta aaaaacgaag tcaaaaattt atctaaaggt agttttgata
      901 agattttagg taaaagttat aaactggaaa aatcgaaagc gattgcaaaa caagtggcta
      961 gaacaaatag tagtatattt atttggggtg aaagtggtac aggtaaagaa gtatttgcaa
     1021 gagctattca tgattatagt gagagaaaag gtcaatttat acctgttaac tgtagtgcta
     1081 taccaaatga gttatttgaa agtgagtttt ttgggtatga atcaggtgca tttacaggag
     1141 caagtaaaaa aggtcgaata ggcatatttg aacttgcaaa ggatggaact gtatttttag
     1201 atgaaattgc cgatttacct cttagtatgc aggcaaagtt gcttagagtg ttacaggaaa
     1261 aagaaataag aagagttggt ggagatacta cgataaaaat aaatcctaga ataatatcag
     1321 ctaccaataa agatttgagt aaaatggtaa aggcagaaaa atttagagaa gatttatact
     1381 atagattaaa tgttgttgaa ataaagattc ctccacttag agagagaaaa gaagacatag
     1441 gattattggt tcatagtttt ttggaggaga tatgcaaaca aaataataag cctgtactta
     1501 caattagcaa agaggtaata gatatatttc agaattatag atggaaaggc aatatcagag
     1561 aattaaaaaa tacgattgaa aatattgttg tattgtcaca aaattctaaa atagatgtgg
     1621 atgatgtacc aagttatatg atggattcta caaataatag tactgaagaa gaagagtatc
     1681 ccttagattt aacgaaggcc actcaaaaaa ttgaaataaa gaatataacc aaggcactta
     1741 aaatgtctaa tggaaataaa gctaaagcag ctaagatatt aaatataccc agaacaacat
     1801 tgtattataa gatagaccaa tacaaaataa atgtgtctaa aatatgacac atgactaaat
     1861 tttgacaaaa tgataaactt taatttaaaa cctagtgaga ccaatgcttg tatgagtgtc
     1921 gtatatatag atgtgttaaa aaaaatgaaa aagtgttgat taattgacac tttttttatt
     1981 tgagaaaatg tttacaaata caaaaaataa catatttaaa ataaatattt atataatatt
     2041 tggctaaaaa tagcgataga tgaagaatct attatagaaa aaatcttttt gttaataagt
     2101 tggcatagga attgcttata atataaagtg actttaagtg agaaaaaaat aatattaatc
     2161 ataacaaatt atgtaggttt taatttactt aatttctcag ttaaggggtt acctgttgag
     2221 gaattgagat ttaaaataat aaataagaaa ataatgtaag gaggtatttt atactatgtc
     2281 aataacttta gaaacagctc aagcccatgc aaatgaccca gcagtttgtt gttgtagatt
     2341 tgaagcggga acaattatag cgccagaaaa cttagaagat ccagcaatat ttgcagactt
     2401 agaggattct ggattattaa caataccaga aaatggatta actataggtc aagtactagg
     2461 agctaagtta aaagaaactt tagatgctct ttctccaatg actacagata acgtagaagg
     2521 atacaaagca ggagaggcta aagaagaagt agtagaagaa acagtagaag aagcagctcc
     2581 agtatcagaa gcagctgtag ttccagtaag cacaggagtt gcaggtgaaa cagttaaaat
     2641 acacataggt gaaggtaaga acataagctt agagatacct ttatcagtag ctggtcaagc
     2701 aggagttgct gctccagtag caaacgttgc tgctccagtg gcaagtgcag cagcagaagt
     2761 agctccaaaa gttgaagaaa agaaactttt aagaagctta actaaaaaac actttaaaat
     2821 agataaagtt gaatttgctg atgaaactaa aatagaagga actactttat acatcagaaa
     2881 tgcagaagaa atatgtaaag aagctaatga aactcaagag ttagttgtag atatgaagtt
     2941 agaaataata actcctgata aatatgaaac ttacagtgaa gctgtattag atatacaacc
     3001 aatcgctact aaagaagaag gcgaattagg ttcaggtata actagagtta tagatggagc
     3061 tgtaatggta ttaactggta cagatgaaga tggagttcaa ataggtgaat ttggttcttc
     3121 agaaggtgag ttaaatacta ctataatgtg gggtagacca ggtgctgctg acaaaggtga
     3181 aatattcatc aaaggtcaag taacaataaa agcaggaact aacatggaaa gaccaggacc
     3241 tttagctgct caccgtgcat ttgactatgt aactcaagaa ataagagaag cattaaagaa
     3301 agttgacaac tctttagtag ttgatgaaga agtaatagag caatacagaa gagaaggcaa
     3361 aaagaaagtt gttgttataa aagaaataat gggacaaggt gcaatgcatg ataacctaat
     3421 attaccagtt gagccagttg gtacattagg agctcaacca aacgttgact taggaaatat
     3481 gccagttgta ttatctccac ttgaagtatt agatggtggt atccatgcat taacttgtat
     3541 aggacctgca tcaaaagaaa tgtcaagaca ttactggaga gagccattag taataagagc
     3601 tatggaagat gaagaaatag atttagtagg tgttgtattt gttggttctc cacaagtaaa
     3661 tgctgagaaa ttctatgtat ctaagagatt aggtatgtta gttgaagcta tggaagttga
     3721 tggagctgta gtaactactg aaggttttgg aaacaaccat atagatttcg catctcacat
     3781 agagcaaata ggtatgagag gtataccagt agttggtgta agtttctcag ctgttcaagg
     3841 tgctctagtt gttggtaata aatacatgac tcacatggta gacaacaata agtctaagca
     3901 aggtatagag aatgaaatat tatctaacaa tactttagct ccagaagatg ctgttagaat
     3961 aatggctatg cttaaaaatg ctatagaagg tgtagaagtt aaagctcctg aaagaaaatg
     4021 gaatccaaat gttaaattaa ataacataga agctatagaa aaagttacag gagaaaaaat
     4081 agtattagaa gaaaatgagc aatctttacc aatgagtaag aagagaagag aaatatacga
     4141 aaaagacgaa aactaaaatt tagatattaa ctaagattta gacaataaca taaatttaga
     4201 tccaagttta aaacagtata gagaggtaga attataatgg ataggttaaa atatatctca
     4261 tcagagactt tttatgaagg tattatagtt gacatcaaag gtggtggagt gactatagac
     4321 ctaaaaggta gacttggaca atttaaaata cctaatagaa tgcttataac tgactacgaa
     4381 cttaagatag gtcaagaagt tggattcatg ctaagctatc ctgaggtatt aagtccagag
     4441 cctaatcaag agtatgtaga aaatattagg agagaaaaag aaaaacaagc agaaatgcaa
     4501 tcaaaacaag aagaaaaata ataaataatc gtttgaaaat agaagggaga ggaaatatat
     4561 gagccttaca acagtacaag gacttcaatc tgaaatattc gttccaataa cacctcctcc
     4621 agtttggact cctgtaacta aagaattaaa agatatgact atagctttag ctacagcagc
     4681 tggtgttcat ttaaaatctg acaagagatt taatctagca ggagatacta catttagagc
     4741 tatacctaat acagctacag ttgatgaaat gatggtatca catggtggat atgacaatgg
     4801 agatgtaaat aaagatataa actgtatgtt ccctatagat agattacatg aattagctgc
     4861 agaaggattt atcaaaggag tagctcctat gcactatgca ttcatgggtg gtggaggaaa
     4921 ccaacatgtc ttcactgaag aaactggtcc tgctatcgct gctaaactta aggaagaggg
     4981 agtagacggt gtagttatga cagctggctg aggtacttgc catagaactg ccgtgatcgt
     5041 gcagagagca atagaggaag ctggaatacc tacaataata atcgcagctc ttcctccagt
     5101 agttagacaa aacggaactc ctagagcagt tgctccatta gttccaatgg gtgctaatgc
     5161 tggtgaacca cataacatag aaatgcaaac acatatatta agagatacat tagagcaatt
     5221 agttgcaata ccatctgctg gtaagatagt tccattacca tacgaatata aagctcacgt
     5281 ttaaaatgta atttatattt gaaaatatag aacccttctc ctacacagtt aggagagggg
     5341 ttttaagaac aaaggtggat attatggaag aaaaaataat aagaagactt gttataaaac
     5401 cgtttcatat gaatgaagtt aatttcggtt caaaaacttc tataaagaaa gatgtactta
     5461 caatagattt atcaagtata gatgaaataa aagaaagaga agagttaata acagacataa
     5521 aagtagacat tataaaacct ggagattatg acagagaaat taatactatt atggacatta
     5581 taccaatatc aacaaaagtt ttaggcagac tgggagaggg aattacacat actttaactg
     5641 gtgtatatgt aatgttaact ggtgcagatg aagatggaaa tcaaatgcat gaatttggtt
     5701 cttcagaagg aattttaaaa gaacaaatgg tatttgggag atatggaact ccatcagttg
     5761 aagattatat aatccatgta gatgtaactt taaagggtgg tttacctttt gaaagaacac
     5821 ttccacttgc agcattcaga gcatgtgatg attttataca agaaataaga gcgtctttga
     5881 aaatggaaga cggaagaaat gctactcaag ttcgtgaata ttttgacaaa attcgaccaa
     5941 atgcaaaaaa ggttgtcata gtaaaacaaa tagcaggtca aggtgctatg tatgacaatc
     6001 agttattctc aaaggaacct agtggatttg aaggaggaac atcaattata gatatgggaa
     6061 atgtacctat gattatatct cctaatgaat acagagatgg tgcccttaga gctatgactt
     6121 aagagaggtg gatattatgg gaataggacc ttcaacaaaa gaaacatctc ttcatcactt
     6181 tagagaccca cttttagaca tagttgaaag tgataaggat gtagatttac ttggagtaat
     6241 agtagtagga actccagatg gaaatgaaaa taaaaccttt gtgggacaaa gaacggccgc
     6301 ttggctggaa gccatgagag tggatggagc tatagtttca tcagatggtt ggggaaactc
     6361 acatgttgac tacgctaaca catttgaaga aataggaaaa agagatatac ctgtagttgg
     6421 agttacattt aatggtaccc aagctaagtt tgttgtaagc aatcaatata tggataccat
     6481 agttgatatg aacaaatcaa aagaaggtat tgagacagaa gttgttggag aaaacaacac
     6541 aaatgaaata gatgctaaaa aagctttggc atttttaaaa cttaaaatga gaaaacatgg
     6601 gtaaaaaatt taagtaagga atgagttttg tgggaatttc tacatcaatg aaaaacacat
     6661 cacttcatat atttagagac ccattactag atttgataga taatgattct gacatagact
     6721 tgttaggagt ggttgtagtt gggacatcag agcacaatga atggaaaaca tttttagcaa
     6781 ctagacttgg aagatggatt gaatcattgc gacctgatgg agtgattata actttagata
     6841 tggcaggaaa ccagcatatt gattttacaa atgctatagc agagtttgta aaatcagata
     6901 tacctacagt aggtcttact attatgggag tagatggatt agtaattacc aatccatatt
     6961 tagataaagc taccataatt gattataaaa agacaacagg ctacatagaa acagaagtag
     7021 ttggagacaa tcatatggac gaagttgatg ttaaaaaagc attggctttc ctaaaattaa
     7081 aaatgcgtaa agacgcaaaa taaacctaag ggggaatttg atatgaaatt tagcagaagt
     7141 atacaagcta tagactctca tacagcaggt gaagcaacta gaatagttgt aggtggaata
     7201 cctaacataa aaggaaattc tatgcctgag aaaaaagaat atttagaaga aaatctagat
     7261 tatttaagaa ctgctataat gttagagcca agaggacata atgatatgtt tggttctgta
     7321 atgactcaac cttgttgccc agatgctgac tttggaataa tcttcatgga cggtggcgga
     7381 taccttaaca tgtgtggcca tggtacaata ggagctatga cagcagctat agaaacaggt
     7441 gtagttccag cagtagagcc tgtaactcat gtagttatgg aagctccagc aggaataata
     7501 agaggagacg ttacagttgt agatggaaaa gctaaagaag tatcattctt aaacgtacca
     7561 gctttcttat ataaagaagg tgttgaagtt gacttaccag gtgttggaac tgttaaattt
     7621 gacatatcat ttggtggaag cttctttgct ataatacatg caagtcaatt aggtttaaaa
     7681 atcgaacctc aaaatgctgg taaattaact gaactagcta tgaaacttag agatataata
     7741 aatgagaaaa tagaaataca acatccaact ttagctcata taaaaactgt agacttagtt
     7801 gaaatatatg atgagccaac tcatccagaa gctacttaca aaaacgtagt tatatttggt
     7861 caaggtcaag ttgacagatc tccatgtgga actggaacaa gtgctaaatt agctacttta
     7921 catgctaaag gtgaattaaa agtaggagaa aaattcgtat atgaaagtat attaggaact
     7981 ttattcaaag gtgaaatagt tgaagaaact aaagttgcag atttcaatgc tgtagtacct
     8041 aaaataactg gttctgctta tataactgga tttaatcatt ttgtaataga tgaagaagat
     8101 ccacttaaac atggatttat tcttaaataa gtaataaata aattaggaaa ttaaaataga
     8161 atagtagcca cttatcggct actattctat agcttttagg ctataagatt cagaatatat
     8221 gaaaaaataa aaaaatagga ggatggatta tggtagcaat cttaaaggca ttatacgtag
     8281 tattcgcagc aatctttgca gttgtgtttg gtaaagacgt agctaaagca aacaaagagg
     8341 ggaaactaga agaacaaagt actccaaaag ttgctgtaac aggatttata acagacttct
     8401 ttgatacatt aggaataggg tcatttgctc caacaatagc aatgtcaaaa gctttaaagc
     8461 taaatatacc agataaaaaa atgcctggta cattaaacgt agcacatact attccagttg
     8521 ttacagaagc attcatattt acatcaatca taccagttga tggtgttact ttagtatcta
     8581 tggttgtggc agcagcagtt ggttcataca taggtgcagg aataatagct aagatggacg
     8641 agagaaaaat acaacttgtt atgggtgtaa ctttagcatt aacagcaata ttaatgttat
     8701 taggtcatcc ttgggttaac gtattaccag gtggaggaaa tgaattaggt cttactggtg
     8761 ttaaattagt aataggtgta ataggtaact ttatactagg agctttaatg acagctggta
     8821 taggtctata tgctccaggt atggcaatgg tttatttctt aggaatgtct gcaaaagttg
     8881 cattcccaat agttatgggt tcttgtgcat tattaatgcc agttgcaagt atgaaattca
     8941 taaaagaaga cgcatatact aaaaaagcat cagttataat agctatatgt ggtttaatag
     9001 gagttttcgt agctgcatat atagtaaaaa ctctaccaat ggatatatta aaagcattag
     9061 taatagtagt tatagcttat acttctgcta caatgataat ggctgcaaat aaaaacaaaa
     9121 agactgctta gttaaagact acttagtgtt tatcaaatat tacagctaat aataaagatt
     9181 ataaactgct ttaaaatatt gaattaatat tttagagcag tttttttatt tactaatata
     9241 taaagcaatt aacatgccaa ttatgtaata tatatagtaa tttagtagat ttaatgtaaa
     9301 aaacgttgta tttttaaata ataaagcata atttaaagct aaatatttaa attttataat
     9361 caataagttt aataaatgtt catatattaa tacagattaa taaaaatata agccgtaata
     9421 agtctaatat aacttatagt taagaaaaat aagtttataa tgacttaata cttatctgaa
     9481 ttatttaaat aagtttaatt ccttgaaatt gcttat
//
LOCUS       DAMKOJ010000116         9498 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000116 DAMKOJ010000000
VERSION     DAMKOJ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.125"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            161..661
                     /locus_tag="PC592_003222"
     CDS             161..661
                     /locus_tag="PC592_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4057158.1"
                     /translation="MIEGIKFIKAEKKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTITKNLPQLFVIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIINLSKEYGYEKIELDVLKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(902..1681)
                     /locus_tag="PC592_003223"
     CDS             complement(902..1681)
                     /locus_tag="PC592_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057159.1"
                     /translation="MNKNILNNSFPEVPESFHNSLNKTLNSLPEREENYKMINNKTHK
                     LPFGKGLVATLAITLILGTTALAVGQISSLVAKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNEEALDKEDNVLGELKALSFEYKNGNDEISLKTANNVLGNS
                     SDNLKVVDTYKDINISYKAFAQKFVPEGYKMTEQDKVDEKSGKYTFSVGPNNESGKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNELVKMVHEVIDAK"
     gene            complement(1678..2157)
                     /locus_tag="PC592_003224"
     CDS             complement(1678..2157)
                     /locus_tag="PC592_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDF4057160.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKFLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            complement(2686..4089)
                     /locus_tag="PC592_003225"
     CDS             complement(2686..4089)
                     /locus_tag="PC592_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4057161.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEVCYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     misc_feature    4794..4936
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            4958..5467
                     /locus_tag="PC592_003226"
     CDS             4958..5467
                     /locus_tag="PC592_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDF4057162.1"
                     /translation="MSKELAINEQIKDKEIRVLSQTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            5495..5689
                     /gene="rpmI"
                     /locus_tag="PC592_003227"
     CDS             5495..5689
                     /gene="rpmI"
                     /locus_tag="PC592_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDF4057163.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAYKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            5745..6101
                     /gene="rplT"
                     /locus_tag="PC592_003228"
     CDS             5745..6101
                     /gene="rplT"
                     /locus_tag="PC592_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDF4057164.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            6402..6947
                     /locus_tag="PC592_003229"
     CDS             6402..6947
                     /locus_tag="PC592_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057165.1"
                     /translation="MNDKLMDCFVNPIKCKLLLEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSVFSVCPVYASIDEIVEASKKIASILEPLKNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            7132..8049
                     /locus_tag="PC592_003230"
     CDS             7132..8049
                     /locus_tag="PC592_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HDF4057166.1"
                     /translation="MRLITRSDFDGLVCGALLKEAGIIDSWKFAHPKDLQDGLVEVTE
                     DDCLANVPFVEGCGLWFDHHSSEFERNKLEGRYKGESRIAPSCARIIYEYYGGNERFS
                     HFNEMLEAVDKVDSGNLTIEEVQNPSGWILIGYLMDPRTGLGRWRNFTISNYQLMEKL
                     IDACRTLSTKEILELPDVKERIEVYFEQTNKFKEMIAKYTRVEGDVIISDLRGVEPIY
                     TGNRFMIYSMYPEQNISAWIVNGKGGKGCSVAVGYSILNRTSSVDVGSLMLKYGGGGH
                     KAVGTCQFNDEQIDELLPKLLDELVNTKN"
     gene            8437..9465
                     /locus_tag="PC592_003231"
                     /pseudo
     CDS             8437..9465
                     /locus_tag="PC592_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
BASE COUNT         3578 a         1100 c         1548 g         3272 t
ORIGIN      
        1 ttttaataga gatacaaaag atagatatat tggttttaat tttatagaaa tatacaaaga
       61 tattttaagc taatatatag taatttatat agcattataa attagaatca tataaaataa
      121 gttaactaca atcataaatt aaaaaagggg aaatgttaag ttgatagaag gcataaaatt
      181 tataaaagca gaaaaaaagt atatttattc gtattggcaa acttttgata aaatagcaaa
      241 agagaggaaa tatctagcta tggatgaggc ctttcctttt gaagaaacag ttgaatttat
      301 aaaaaatact ataactaaaa acttaccaca actgtttgta attgatttag aatcagataa
      361 ctgtattggt tggtgcgacg ttttacctaa aactgaaaaa gttggttatt taggcatggg
      421 tattcttaaa gagtataggg aaaaaggcat tggaagtagt cttttaaaac aaattattaa
      481 tttatcaaaa gaatatggat atgaaaaaat tgagcttgat gtgttgaaaa gtaatagtag
      541 agctattcat gtttataaat ccttagggtt tgtagaggta aatacaatat ctagtggttt
      601 tacatggaat gatagacctg taaaagaaga ggtaattcaa atggagctta cacttatata
      661 aaataaagtt aaacccctta aaattccata tacacttata taaaataaaa ttaaagccct
      721 taaagttcca tataaattta agggcttttt aatagtgctt cttttgaaag tagttaaata
      781 tctaaaattt tatatattaa atttaaagaa aatataaaga tggaagatac aaccatgttt
      841 gctaataaaa aaattaaagt cgtaaataat aaactcataa acaacttatt attacttatg
      901 tttattttgc atctattact tcatgaacca ttttaactaa ttcattcata gataaatttg
      961 agtcttgaac tgtaaaagaa tagtaaactc catcttgttt ccatgtcaaa aacttaaatt
     1021 cattaacttc aactttacct gattcattat ttggacctac actaaatgtg tatttacctg
     1081 atttttcatc aactttatcc tgttctgtca ttttataacc ttctggtaca aacttttgtg
     1141 caaatgcttt ataagaaata ttaatatctt tgtaagtatc tacaactttt agattgtcag
     1201 aactatttcc aagtacatta tttgctgttt taagtgatat ttcatcatta ccatttttat
     1261 actcaaaact aagtgctttt aattctccta aaacattatc ttctttgtca agtgcttctt
     1321 catttacagt atatgcacct ttaaatttat atccattact aaattcagaa actatattag
     1381 gggtaaagtt aaagtctttt tttacttgtt ctgtagttgg gatagatgta taggtagctt
     1441 tagtacttga ttttgcaact agactagata tctgccctac tgcaagagct gttgtgccca
     1501 atattaaagt aatggccaaa gttgcaacta agccttttcc aaatggtaat ttatgtgttt
     1561 tattattaat cattttataa ttttcctccc tttctggtaa actatttagt gttttattta
     1621 aactattatg aaaactttct ggaacttctg gaaacgaatt atttaatata tttttattca
     1681 tatgattacc tccgtgtttt ctaatttagt ttttaataat cttcttcctc ttgataatct
     1741 actttttaca gttccttgag gtatatctaa tatttcctta acttcatcta ctgaataacc
     1801 ttcaatatag taaaggacta ttggaatttt aattttttta ggtagacttt gaatagcagt
     1861 atacaaatca ctataatcat ctttttcatc aatttttttg tttttgaaga cgtcttcaaa
     1921 tgatagaaat tttaatcgtt tacgtcttaa tgaattacat tcatttatga ctattctaat
     1981 caaccaggtt ttaaagtatt gttcttcttt aagagaatcc aacttttcat atgcttttaa
     2041 aatagcattg ttgacggcat cttcacagtc ttggtcgttt cctagaatag acttagatac
     2101 tcgatacaaa gtctgttctg attcaagtat attgtttgta aatgtagttt tatccaattg
     2161 agttcctacc tttctatgca aatcgtagcg ctactttttt gcctttcact tattagataa
     2221 aattttacta tagatggttc actttcttta taattatttg ataaatttaa gtttaaaagt
     2281 tttgtctatt ctatacaaat attctataat atattttttt acagtcatat ataaagccat
     2341 gtatatatga aactttagaa gctatttata tatttagttt tatagtaagt gtttatattg
     2401 agtaattaga aaataataag tatttatgtt gagtagttgg aaaataaata atatttttga
     2461 attatttaat tcatgtatag atttaaaata agttctttaa atagcgactt taaatagata
     2521 taagtcataa attaaataga caaaattaaa agatggaagt atatcaaaat gaatttttta
     2581 gttcataagg cgttttttgt atgaaatcaa ataagttttt ataattttaa caataaaaag
     2641 aggcttatct ctattttgag atagcctcat atttttaaaa ctatactagt ttacagcttc
     2701 ctttcctatc aaatctttta actcttcatg agtcatagtt tctttttcaa ataagaattt
     2761 agaaacagaa tgtaaatctt caagattatc ctttaacatc tctaaagtct ctttataaca
     2821 aacttcaact atacgatttg cttccttttg aactttatca cataagaaag tcttatcatt
     2881 tccatcaata gtcataaacc ctaaattact cataccgtat tcacaaacca tttgattagc
     2941 tatttcagtg actttcttta agtcgtcctt tgcaccagta gatttatgat taaatattaa
     3001 ttcttctgaa gcctttccag caagtaatat ttttattttt ccaatcaatt catccttagt
     3061 ataaatatat ctatcttcat caggtaattg aagaacataa cctaatgctt gtcctctagg
     3121 aactatagat attttttgta taggacaaat tcctactata tcacttacaa gagcatgtcc
     3181 agcttcatga tacgctacta tttttttctc tttttcaacc aatgcagagt ttttagattc
     3241 tagccctgca ataactcttt caagtgcctt gtcaaaatgt tctgatgtaa tacactcact
     3301 gtcatctcta actgcaaata tagctgcttc atttgctata tttgaaagat gagccccatt
     3361 aaaaccatga gtttttttag ctaaaagttc tagatttaca gatttgtcta taggtttgtc
     3421 atctgtatgt acctttagaa tttcaaatct agtgtgataa tttggtgcac ctatatgaat
     3481 gtgtctgtca aatcttcctg gtctaagtaa agcttcatct aataagtcaa gtctattggt
     3541 agcacctatt attaatacat tggaatcttt attaaatcca tccatttcaa ctaaaagttg
     3601 gtttagtgtt tggtcttttt cgttgttact ttcaagatgt ctttttgctc ccacagcatc
     3661 tatttcatct ataaatatta tacttggagc ttcttttcta gctttttcaa atagagttct
     3721 aactcttttt gctcctacac ctacatattt ttcaacgaac tctgaaccag taacattgaa
     3781 aaatgatgag tttgtttcac cggctacagc agatgcaagt agagttttac ctgttcctgg
     3841 aggaccataa aataatactc ctttaggtat ttttgcaccc attttttgat atttttgtgg
     3901 tgatttcata aaatcgacta tttcaaatag ttcttctttt acttcgtcta atccagcaac
     3961 gtctctaaat gtagtctttg gttttgtaga aagtgaatca tctgtttgat tgtctctttc
     4021 catttttgtt tgtgcaaaga caggagctgg attgttaatt ttcttaaaaa agttgtttag
     4081 cattttcata ttcacacctc aggtaattaa ttattgttaa tcaattttat attttccata
     4141 tttactattt tttattattt atttttcatg gaaaaaatat acatgttatc taaataaaaa
     4201 taaacttgta agatgtatga aaaagtgaat ttatgtatat agagatttct atttgtgtat
     4261 tgaataaagt aatacaaatt ataaattatg tattgattat atgttgagta aagtattata
     4321 aagcatgtat tgattaagta ttgaataaaa tattacaaat ttagatgaaa tgaaaatgat
     4381 aaaaaatgtt gtactatact ttacaaatca tataaatgga aaaattgtta tagcacaaaa
     4441 tagtgagtag catattagaa tataatatag aatttgttgt gcagtatagt agtatattag
     4501 aatataatgt agaatttgtt gtgtagtata gtagtatatt agaatataat atagaatttg
     4561 ttgtgtagta tagtggtata ttagaagaca atataggatt tgttatgtag aatatatgga
     4621 gtcatttaga atatacatat tataaaagga ttttgggtat aaatttaaaa attaatagca
     4681 aaatgagtag tatagacata taattagtag taggaagtaa ttaaattttt cctaaaccaa
     4741 aaaaaacagt tgcaaataat ttgattaagt gatatagtaa ataaggtaag aataaaacaa
     4801 agaagaagtc cgcttctcac cttacgccag aggttagtaa ggtaaatata agttaaagct
     4861 taatttcaat ttaagcttgt ttaaatttgg taacttatat tgcggatgat tacgtcatcc
     4921 gctttttatt ttataaaaat tttggaggtg tcctacaatt agcaaagaat tagcaatcaa
     4981 tgaacaaata aaagataagg aaataagagt cctttcacaa acaggtgaac aacttggagt
     5041 aatgcctact aaagaagctc aagcaatggc taatagcaaa aacttagatt tggttcaaat
     5101 ctcgccaaat gcaaatccac cagtatgtaa gataatggat tatggaaagt ttagatatga
     5161 gcaagcgaga aaagagaaag aagctaagaa aaaacaaaaa actatagttg taaaggaagt
     5221 aagacttaga ccaggtattg aacaaaatga tttaaatacg aaagctaata atgctataaa
     5281 gttccttaaa aaaggggata aagtcaaagt tgaacttaga tttagaggaa gagaattagg
     5341 acataaagac ataggtaaag aagttatgct taagttttta gatataataa aagagtttgg
     5401 agaaccaaca aaagcccctg catttgaggg taataatatg gttgtaatta tagatccaaa
     5461 aaaatagatg attaactgag aggaggaatt tgtcatgcct aaaatgaaaa ctcatagagg
     5521 tgcagcaaag agattaaaga aaacaggaac tggaaagtta aagagagcta aagcttataa
     5581 aaaacatata ttaactaaaa aatctgcaaa aactaaaatg aacttaagaa aatcaacttt
     5641 agtaagtgat ggagatgcta agagaatagc acaattatta ccatactagg atacagatta
     5701 taaataataa ctatagaaga gggatataaa aggaggtcat aacgatggca agagttaaaa
     5761 aagctatgaa cgctcgtaaa aagcataaga aaatattaaa acttgcaaaa ggattcagag
     5821 gatctagaag caaattatat agaccagcaa atacattcgt aatgaaagca ttaaaaaatg
     5881 cttatatagg aagaaagtta aagaagagag acttcagaaa actttggata caaagaataa
     5941 atgcagctgc tagaatgaat ggaatatctt attcaagatt aatgaatgga ttaaaattat
     6001 ctggtattga agttaacaga aagatgttat ctgaaatggc tatacaagac ccagaaggat
     6061 ttgcaaaatt agcagaagtt gctaaagcaa aattagctta gtattgaatc atgagatgta
     6121 aagtctttga gttatgtaaa taattcaagg gcttttttat tttttgaaaa atacttatta
     6181 gtgccatata cattcaattt tataatgata aataaaataa gagatacaat agagtttgct
     6241 cagatttaat ataaaaatta ttacaattat ctataataac tatagaaagt tattttaaaa
     6301 ataacattga tatatgtata aagtttccag ctaatcttga attaatatta tcaatatgat
     6361 aatattatct tgttaagaat atatgtagag ggagagataa tatgaatgat aaactgatgg
     6421 attgttttgt aaatccaatt aaatgcaagt tattacttga aattttttca aataatagaa
     6481 cgacagctaa acaattagga gaaaaatttc aagatatatc aaaggcaaca ctttatcgtt
     6541 accttaataa aatgttgaaa gatgatatta taaaagttgt tgaagaaaat aaaataaggg
     6601 gaactgttga aaaagtatat gctatgaagt tagatatagc tgatgatgtt aacaaaatta
     6661 tagatgagaa ctctggagaa gaatatgctc aactgttcac tcaatatatg atgggatttt
     6721 taagagaatt ttatgaatat gctgaaagaa aggaaaagga tatcctaaaa gatggttcag
     6781 ttttttctgt ctgtccagta tatgctagta ttgacgagat agttgaagcg agtaaaaaaa
     6841 ttgctagtat actagaacct ctgaaaaata attcacatga agaaggtaga agaatgcatt
     6901 ctataggagt gataattact ccacctaaag aagatgaagg taaataaatg ataaaagtaa
     6961 cagtttgatt tttatgacaa gctgttattt taatgtatag tattttattt ataatatttt
     7021 attttaatgt atgcaataaa atgtatatta agctggcata taaagtgata tgatatatct
     7081 aagggaaaat tgtatatata tgacatattt aaaacacagg ggatgaaaat tatgaggtta
     7141 attacacgtt ctgattttga cggattagta tgtggtgcat tattaaaaga agcggggatt
     7201 attgatagtt ggaagtttgc tcatcctaag gatttacaag atggattggt tgaggtaaca
     7261 gaagatgatt gccttgcaaa tgtaccattt gttgaggggt gtggtctttg gtttgaccat
     7321 cactctagtg aatttgagag aaataagctt gaaggaagat ataaaggtga aagtcgtatt
     7381 gctccttctt gtgcgagaat tatttatgaa tattacggtg gaaatgaaag attttctcac
     7441 tttaatgaaa tgttagaagc agtagacaaa gttgattctg gaaatctcac tatagaagag
     7501 gtacaaaatc catctggctg gattttaatt ggttatctta tggacccaag aacaggattg
     7561 ggacgttgga gaaattttac tatatctaac taccaattaa tggaaaagtt gattgatgca
     7621 tgtagaactt taagtacaaa agaaatttta gaacttccag atgtaaagga gcgtatagaa
     7681 gtttattttg agcaaacaaa taaatttaaa gagatgattg ctaaatatac acgtgtagaa
     7741 ggagatgtta ttatttctga tttacgtggg gtagagccaa tttacacagg gaatcgtttt
     7801 atgatttaca gtatgtatcc agagcaaaat atttctgctt ggattgtaaa tggtaagggc
     7861 ggaaaagggt gttctgtagc tgttggatac agtattttaa atagaacttc gagtgttgat
     7921 gttggtagcc tgatgcttaa atatggtggc ggtggacaca aagctgttgg aacttgccaa
     7981 tttaatgatg aacaaataga tgaattgctt ccaaagctac ttgatgagct tgtaaacact
     8041 aaaaactagt ggataaactt ataaatttta aaaactacta cgaataaaat agaacttcat
     8101 tgtaccattt catttaatga cttggagtga tacaatgaag ttttttaatt tttcatatca
     8161 ataactaaag aaataaactt tagaccacat atacaattag gttacattat accattagaa
     8221 cagatatata aaataaaaaa tcagtatttt tatagcagac aaattgactg ttattctttt
     8281 taaaagtcat atattagttg ttgttagatg gcgaaaaaaa ttataggaaa ctattgaata
     8341 aatgaatatt gcctataatc atataaactg ctatagttta aaataaagca gaacgttaaa
     8401 ttttattata atcttaaaat ttaagagggg gattttatga aaataaaatt tgttattatg
     8461 acattagtga tatttttaat agcattacta gtgggatgtc aaagtacaaa agatacagaa
     8521 gttaaagtaa aagatacaga aattaaaata ttagggacag gtgatttaca ttcaattttg
     8581 acagactcta tggtttcata tgtaaatgag gaaagggaaa agaataaaaa tctgattatg
     8641 gtagatgcag gagatttcta tggtacacaa agtagagaaa tgtgggagtg gtcttctgga
     8701 aaaaagttaa ttaatattag aagagatagt agggcagagt atgatgacat aattaagaat
     8761 agtaaagatg aagtacctat agttaaagag atggcaaagt tgaaatatga tgctgtagtt
     8821 ttgggagata atgaatttgt ttcaaatgat aagcaaagtc ttgataaact agtttctgat
     8881 tttaaaaata ataatatgcc attggtatca gcaaatatat atgaacaatc tggagaaaat
     8941 tatgtacaac catatgtaat gaaaaatatt aagacagatg agggcaatgt aaaagttgga
     9001 atactaggtc ttactataaa agaagtaggg gaaacccttg gtcttgaaga ttttgaaaag
     9061 gataaaaaag caagagcgtt aggagaacaa gctgattaca aaggaaaatt atatgcaaat
     9121 gatttaatag aggatgcaaa gaaatggata aaagttatga aaaaagaaag tccagacata
     9181 atagttgcag ttgtacactc aggggaagag cataaaatgg atagaaatcc aggaaataga
     9241 ataaaagagt tagcaactac agtggatgga atagatgtaa ttgtagctgg tcatactcat
     9301 gaaaaaatag atgaacataa atataaaaat aaatctggag atgaagtaat tgtcacacaa
     9361 ccaggttggc atggagatag agtgtcagag attaatttca aattaaataa agaaaatgac
     9421 aagtgggtta taaaggaaaa gtctagtaaa ttaaaaatga ttgattaaaa aatagctacg
     9481 cacacttgtg actttagt
//
LOCUS       DAMKOJ010000117         9388 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000117 DAMKOJ010000000
VERSION     DAMKOJ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.126"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            358..1563
                     /locus_tag="PC592_003232"
     CDS             358..1563
                     /locus_tag="PC592_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF4057167.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTDHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     TVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLISRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1634..1855)
                     /locus_tag="PC592_003233"
     CDS             complement(1634..1855)
                     /locus_tag="PC592_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057168.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(1997..2596)
                     /gene="recR"
                     /locus_tag="PC592_003234"
     CDS             complement(1997..2596)
                     /gene="recR"
                     /locus_tag="PC592_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDF4057169.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2609..2959)
                     /locus_tag="PC592_003235"
     CDS             complement(2609..2959)
                     /locus_tag="PC592_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDF4057170.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3018..4655)
                     /gene="dnaX"
                     /locus_tag="PC592_003236"
     CDS             complement(3018..4655)
                     /gene="dnaX"
                     /locus_tag="PC592_003236"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDF4057171.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4732..4996)
                     /gene="ffs"
                     /locus_tag="PC592_003237"
     ncRNA           complement(4732..4996)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PC592_003237"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5034..5125)
                     /locus_tag="PC592_003238"
     tRNA            complement(5034..5125)
                     /locus_tag="PC592_003238"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5089..5091),aa:Ser,seq:gga)
     gene            complement(5126..5581)
                     /locus_tag="PC592_003239"
     CDS             complement(5126..5581)
                     /locus_tag="PC592_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDF4057172.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5903..7174)
                     /gene="serS"
                     /locus_tag="PC592_003240"
     CDS             complement(5903..7174)
                     /gene="serS"
                     /locus_tag="PC592_003240"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF4057173.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEKEFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKNIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYALM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIR"
     misc_binding    complement(7299..7505)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7633..8514)
                     /locus_tag="PC592_003241"
     CDS             complement(7633..8514)
                     /locus_tag="PC592_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF4057174.1"
                     /translation="MNFLSLAKSASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDLVKSILNEIFINEKR
                     ILDDPRPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENNIKVPFVP
                     SSLLFNNMSNLNTMDKR"
     gene            complement(8526..9035)
                     /locus_tag="PC592_003242"
     CDS             complement(8526..9035)
                     /locus_tag="PC592_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDF4057175.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIAII
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9163..9279)
                     /gene="rrf"
                     /locus_tag="PC592_003243"
     rRNA            complement(9163..9279)
                     /gene="rrf"
                     /locus_tag="PC592_003243"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3010 a         1652 c         1003 g         3723 t
ORIGIN      
        1 catctttatc ctgtctagtc aatataattt tttaattttt ttatttatca tatattcttt
       61 atatttaatt tccaaaacct aatgctaaac aaatctgttt atttcataaa actaatatat
      121 attctatgct ctattttcct ttttattcta tatttaaatt ttttatttac aataatattt
      181 ttaacataac atatttgata aaattaaatt tcatttcttt cacttgtaat ttttgtaatc
      241 ttgtattaga ttaatattaa aaaatagttt atcaataacc ttatttacaa agacagtttt
      301 atatatcaaa acataataca atataaatac tatgctacat tttaggagga ttttattatg
      361 agcaaaaaag tattaataat gtctgcttcc actggtggtg gacacaatag agctgctcta
      421 gctattaaag aagaacttac ttcaaaaaca cttgatggag agccaattga atgcgaaata
      481 atagatagtt tgaaattagt taataataca atggacaaga taatttcaag aggatacgaa
      541 aaatctgcta tatatactcc caaagcctat ggaagtgtat atagattatc tgaaacaaat
      601 cttttatcaa aaaatgaatt taaagataat ctactaataa cattcatggc taaaaaattt
      661 aaaaagctta ttagaagcga aaaaccagat ttgattatag gaacgcatcc ttttccaatg
      721 attgctctta gtacattgaa aaaaaacttt aatttacata ataatgaatc aaatgcttat
      781 acagatcatt tttataaaca ttatacaaat accattaatg ttcctccgct tatttctgta
      841 ttaactgatt atactactca ctctacatgg atacaaaatg aaattgatta ctatattgtt
      901 ggtcatgaat atgtaaaaga actattggtg tttgatggag ttgaaccgag taaaattaga
      961 acatttggaa tccctgttga aaaatctttt ctctctcaca gagataaaga tactgttctt
     1021 tctgagttga atctatctcc tgataaatta actgttttac ttatgggggg gagctttggg
     1081 gctggaaata taaaagaaac tcttgatgaa ttattggata ctgatagaga ctttcaaata
     1141 cttgtaatta ctggtaagaa tgaaagccta aaagaaaaaa tcgaaaaaaa acttatatct
     1201 cgttatcatg ataaaaatgt atgtgttctt ggatatactg ataagatgaa tgatatttta
     1261 gcttctatag atgtattagt aagcaaacct ggtggactta ctacaactga ggctctttta
     1321 aaagatgtac ctatgatagt tccttattat ataccaggtc aggaagaaga aaatcttgat
     1381 ttcttatcta attgtggtgc agcgcttaga actacaaaaa aatataactt gtcaatatta
     1441 ctaaaagttt taatagatga ccctagcaga ttagaaatgc taaaaagaaa tattaaatca
     1501 ataagaaagt caaattcagc ccaaaatata gctaatttaa ttttaaatat aatttctggt
     1561 tgataaaata aataaaatcc ctatagtata tatattatct attagggatt ttttattttc
     1621 taattattta atattaaatt ggttcataaa agtcttcttc gtaatcatac tgataatttt
     1681 tataattatt tctaaattca gcatttttat ttcgtacatt ttttttagtt tttttcttat
     1741 tagaaaaact tatatcctca aaatcatcat atttaggttt atcttttgat ttcatttttt
     1801 taactctttt ttctttcatt gcattatgtt cttctaagtt cataattggt ttcatgttgc
     1861 acccctatca aaatttttaa atgatttata caacaaatta tacaatacag aagaaattta
     1921 ttcaataaat ctaaatcaaa attaatttga atttaaccca aaaaaattac aaaaatcgag
     1981 gtattaacct cgatttttat atttctcttc tgccttctag tgcttttgat attgtgacct
     2041 catctgcata ctctaaatcg cctccaacag gaagaccatg agctatccga gtgactttga
     2101 ttcccattgg ttttactaac ctagcaatat acatggctgt agcttcacct tcaatagtag
     2161 gatttgttgc cattattatt tctttgactt cctgattgcc aagtctttgg ataagttcct
     2221 ttatttttaa catatctggt ccaattccat ccattggaga aattactcca tttaatacat
     2281 gatactggcc tttaaactct ctcgttctct ccatagctgc tacatctctt ggatcttcca
     2341 caacacatat aacacttgaa tctctacttt tatttgaaca catgctacat gggtctgtat
     2401 ctgttatatt acaacaaatt gagcaatatc ttatttctct ttttgcatct ataatcgctt
     2461 tagataaagc ttccacatca ttagtattca tgttaataat atgaaaagcc aatctttgag
     2521 cagtctttct tcctactcca ggaagctttg aaaattcctc tataagtctc gttattggac
     2581 ctgtataaac ttgcataaat accacctact agaataaccc aggtatattc atacctccag
     2641 ttaccttact catttgactt gcttgtatat catcaatatt tctcaatgct tgatttactg
     2701 cacttaaaac taaatcttgt agcatttcta tatcatctgg atcaactact tctggtttga
     2761 tagttatatc tataacttct tttttaccat taacttttac agtaactgct cctccaccaa
     2821 ctgaagcttc tacttcttta ctttctaact cttgttgagc tttttgcatg ttttcttgca
     2881 ttttttgagc ctgctttaac aagttgttca tatttccacc accaggcatc attccgcctc
     2941 caaaaccttt tttagccata aacactattc ctcctaaact tattttcatt ttattattat
     3001 atcataatag tattttatta tttactctca ttttcatcaa tactatcttt tatttctaat
     3061 atctcttcac tcactatgtt ctttaatatc tcttcaccaa tgtccttttt ctctttaact
     3121 tcaagattta tatctttaac ttctgatgtc agtactattt ttacattaaa acttctattt
     3181 aaaacatctc ttattgtttt ttctaaataa tttattgtat cttgagagct cagtctagtt
     3241 tttgcaaaat caaatttatc atcaaatata acatacaaca tattagaata tacattaaaa
     3301 ctttttactt cacttaagag tgcgtatatt ggcatttttt tatctttttt aatttgttta
     3361 agtatattct tccaagatga ctctataagt ataacgtcct cattttttac atcttcataa
     3421 actacatttt cttgttttac atctatttct ctatcaacct catactcttt ttctttatta
     3481 ttcccaattt tttcagactt aaagttcccc agttcaatca ttttttctag gttctcaact
     3541 ctttttataa gagcttcttt actttcatca aacattggtt gagcaatttt cattatggtt
     3601 atttccacta aaacccttgg atttgaagat gactttatat catcctgagt tattgataat
     3661 atatttaaaa tccttattaa atcatttata tctatatttt tagattgaat tttaagttgt
     3721 tctatagttt cttctggtaa tgaaattatt tcatccaatt ctgatgaaac cttacatacc
     3781 attaaatttc taaaatgatc aattaaatca tttataagat ttcttatatc tttgccccat
     3841 aagacaaatt catttaatat ctcaagagac tttttagtgt cctgctctac aatacattga
     3901 gacaattcaa ataattgttc tatatttacg cttcccatta attcaacaac atctttataa
     3961 tctatcttac tttctccaaa agacatacat tggtctaata tactaagtgc atctctaaga
     4021 gctccttgag aatttctagc tattaaatta agagctttat catctatatc aattccttca
     4081 tcttcacaaa tctttttcat tctaagggtc atatctttaa ctgtaactct tttaaaatcg
     4141 tatctttggc atcttgataa aatggttgca ggtattttgt gaggctctgt agttgctaat
     4201 ataaaaatta catatgatgg aggttcctct aaggtcttta ataatgcatt aaaagctcct
     4261 tgagacaaca tatgaacttc atctattata tatactttat atttagcatt ggccggagaa
     4321 tatttcacac tttctctaag ctctcttata tcatctacac tgttatttga ggctgcatcg
     4381 atttctacaa catccattgt attatctttt aatacagatt cgcatatctc acactcatta
     4441 cacggttctt catttatttt attcaaacag tttactgctc tcgaaaaaat ctttgcagta
     4501 gatgttttac cagtacctct tgttccacaa aacaaataag catgtcctat attatcacta
     4561 tatatttggt tttttaaagt cttaataata tgatcttgac caataacatc ttcaaacttt
     4621 tgtggtctat atgctctata taatgcttta tgcatctttt tacctctctt tagcaaaatt
     4681 aataaaaaaa tccctcatta tctaagggat tagtctttta tatattaaat gctgtacacc
     4741 atctatcgac ttaattccat aggcgttacc aaaacagtta gctcaactta ggcaccccca
     4801 cggcacacaa aagtgatcac ttaccgctgc ttccttccgg atctgacggg gttcatgagc
     4861 tttcattgcg caggacctaa gcatcaacac cacttattta gggcggccct acagaaaata
     4921 agcctttaga tggaattcaa tcctgctata gcggattgca ggttacaggg caccgctacc
     4981 tccccatcta gtacagcaaa attacaacca tatttaatta ctttcattgt ttctggcgga
     5041 gagagtggga tttgaaccca cgatacagtt ttacccatat actcgctttc caggcgagcg
     5101 ccttcgacca ctcgaccatc tctccttaat ctctttttct caatgcctta aaaaattctt
     5161 gcaatatgat cgagcattct tcttgcaaaa catcaaaagc tacttttaca ttattattat
     5221 taaaataatc taatttaaac tcatgctgtt tctctatata tgaatttttt acatgtcttg
     5281 tccctattat aagctttttt attctagaat taactattgc accactacac attatgcaag
     5341 gttccattgt aacatataaa tcacaatcag tcaacctcca accacctaat ttttctgatg
     5401 cttgttttat cgctaaaatc tctgcatgag ctgtagagtc ttttaacgtt tctgtaaggt
     5461 tatgagctct agctattatt tgattatctt taactataat agcacctatt ggtgtttctt
     5521 ttttattata tgctttatat gcttctttta atgcttcttt catataaaat gaactttcca
     5581 taattcctcc caaaacttat aacaaactta tcttatcata attcatttta taattcaact
     5641 taattttatt ttgtttattt aattatcact atatatagct atattttttt aatattagtt
     5701 ctaaaataat ttttagatat ttatacaaga gtattttata aaaatattta gtgttttatg
     5761 atgaaaattc tgtcatataa attaacataa aaaaactatg aaatttaata tttacaacaa
     5821 tttcatagtc ttttaattta ttgtttactc ataacatctt ttcttcatta aagcatattc
     5881 tatacataca attaatataa aattatctta taacatcaac acccatataa ggtcttaatt
     5941 cttctggaac tactacagaa ccatctgcct gctgataatt ttctaatata gcagccaaac
     6001 atcttcctat cgctaatcca gaaccattca atgtatgaac atattctgct tttgattttt
     6061 tatctctttt aaatcttatt cctgctcttc ttgcttggaa atcttcaaaa tttgaacaag
     6121 aagatatttc tacatatcta ttgtaacttg gcatccaaac ttctaaatcg tatttaaatg
     6181 cagctgtaaa tcccaaatcc cctgtacata tttttacaac tctatatgga agacctaaca
     6241 tttgcaacat agtttcagca tcatgagtta atgattctaa ttcattataa gaatcttctg
     6301 gttttacaaa tttaactaat tcaactttat taaattgatg ttgtctaact aaacctcttg
     6361 tatctcttcc tgctgaacct gcttcagatc taaaacaagg agtatatgca caatatttaa
     6421 ttggaagttc tgcaacatct aatatctcat tagcatgtat attagtaaca ggtacttcag
     6481 ctgttggtat taagaaatac tctaatcctt ctatcttgaa catatcttct tcaaatttag
     6541 gaagttgacc tgtacctata aaactatttc tattagccat aaatggaggt aaaacttctg
     6601 tatatccatg tttagctgta tgagtattta aaaagaaatt cattaaagat ctttctaatc
     6661 tagcgcctaa acctctatat aaagtaaatc ttgaaccagt tatttttcca gctctttcaa
     6721 aatccaatat acctagacca gtaccaatat cccaatgtgc tttgtgttcg aaatcaaatt
     6781 tagtaggctc tccccaagtt cttatttgaa cattatcttc atctgtttca ccttgtggta
     6841 cctctggatg aggaacattt ggtattctca tcaatgcgta ttccattttt gcttctactt
     6901 cttttacttt ctcatcaata ccttttattt tatctgataa ctcttttaac cttgcctttt
     6961 cttctgttac atcctttcct tcttttatta attgtggtat atttttagaa tttacattta
     7021 attcattttt cataacctca acttcttgaa gtatctctct tcttttatta tctaattcaa
     7081 ccacagcatc aaggtcaaat tctttttcgc ctcttctttc catagctttc ttgatatcat
     7141 ctaaattttc tcttattctt ttaatatcta acatattaat tcctcctaat aattttgata
     7201 atataaatta taattccaat taatttacaa ttattctagt tgtaaacctt taatttaaac
     7261 aaatttgaaa aataaaaaaa gacctccgtt taccctataa aagggacgaa aatcttttat
     7321 ccgcgttgcc accctaattg attatactaa aatgtataat cctctcagac ctataacgta
     7381 ggtaaaccgt ctagctttaa ctagaagctc tagagtagat tcaaaaacca ttgtaatgag
     7441 ttctcaccat ccactcattc tctgaataca atctgttttt tactattttc cttcacagct
     7501 ttttaactaa ttgttttatt tgataatcat tatattatat atattaacat ctttcaatac
     7561 tattattcaa atttttttag aattttcttt aattttttat attaaattca ctttttttac
     7621 ttaattaaaa ttctatcttt tatccattgt atttaaattg ctcatattat taaataataa
     7681 tgaggaagga acaaatggaa cttttatatt attctcatca aatttatttt tgactttttc
     7741 cattacatca aaataaacat cccagtaatc atcagtttta acccatggtc tagcaactat
     7801 ttgcatggta ttatttccta tagagtttaa acctataatt ggtcttgggt catccaatat
     7861 ccttttttca tttataaaaa tttcattcaa tatagactta actaaatcga tatcactatc
     7921 atatgaaata ttatatgaaa aatctatcct tcttttattt tgatgtgtgt aattaattat
     7981 attgttactt gtcaattgaa agtttggtat aattatggtt ttattatctg gagtcttaag
     8041 aacagtacta aatatttgta tgtcagaaac tgtaccttct acacctgaac cttgaatata
     8101 atcacctata ttaaatggct taaaaaacaa aataatcatg cccgaaccta aatttgataa
     8161 tatttcttta aatgctaaac ctatactaaa tccagcagct cctaacacag ctacaactga
     8221 tgtagtttgt attcctataa tccctaaact tatcaatgat ataatagata acatagatat
     8281 atatattcca tatacaatga aattatttac acctttactc attccatatt tgattagaaa
     8341 ctttgaaacc atccttctta ctattttaga tatataaata cctatcacaa atacaattat
     8401 tgcatatata atatttggta tattatcact aaaattatcg agcatatttt ctaaagttct
     8461 cttagttatg ttactatttg ttgaggcaga cttagctaat gataaaaaat tcatttaact
     8521 cctccttacg ataagattcc gttgtccttt aactctttta ctatagcttc tatagtttcc
     8581 tcttttattg cctcaattgt atgaatatgg ctacattctg tcagaaccga taattgttta
     8641 aattcattag tctcaacttt cttcataaag ttgtctatat ccattttaga ataaatatta
     8701 agttctgctg ttatctgacc atatgttgga tgatttacga tgacatcttt tataatacca
     8761 cctaaatcta caattatctt taattcatca taaatttctt tagaatcttt atggttttta
     8821 cattttattt gttttgtaaa atacggttga ttatatatta tatatccttg aggtgtagct
     8881 attatttcaa atcctctagc tcttataatg gctatatctt gtactattac ttgtctactt
     8941 acatttaata gttcagctag tgttccacct tttacaggat gcttagattc tttcaaaata
     9001 tctattaatt tacttcttct ttcattagaa ttcatattac accttctttc caaatcaaaa
     9061 actttaccta tattatataa ttctatattt tatcttatta taaatcaata ttgactttat
     9121 attctattta atcttaattt ttataataaa tgaaaaaaga ctacgtggct acgtcctact
     9181 ctcccaggca gtttcccacc aagtaccatc agcgctagag agcttaactt ctgtgttcgg
     9241 aatgggaaca ggtgtatcct ctctgctatt gtaaccacat aatctttatg cttaatattt
     9301 ctattaagtt tttaataatt ttttagaatc tagtaatact agttctttta gagttaacac
     9361 tctaaaaact acacatatat cttagtaa
//
LOCUS       DAMKOJ010000118         9040 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000118 DAMKOJ010000000
VERSION     DAMKOJ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.127"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            209..1585
                     /locus_tag="PC592_003244"
     CDS             209..1585
                     /locus_tag="PC592_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDF4057176.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSRGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVGKRRFSKLNVHSKVVLFSTATLILVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPATIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            1885..2556
                     /locus_tag="PC592_003245"
     CDS             1885..2556
                     /locus_tag="PC592_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDF4057177.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            2743..3540
                     /locus_tag="PC592_003246"
     CDS             2743..3540
                     /locus_tag="PC592_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDF4057178.1"
                     /translation="MITNINSKDNEKLKYTKALLKSKNRNKESKFIIEGYRIVVLALE
                     CMANLDYVFINEDFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVEAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIINASQDETVDMLKSLDFNIVSSYLNTDNFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKSLI"
     misc_binding    3801..4035
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4085..5104
                     /gene="pheS"
                     /locus_tag="PC592_003247"
     CDS             4085..5104
                     /gene="pheS"
                     /locus_tag="PC592_003247"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDF4057179.1"
                     /translation="MQEKLLALREVALAEIKEAQSIESVESLRVKYLGKKGDITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            5121..7514
                     /locus_tag="PC592_003248"
     CDS             5121..7514
                     /locus_tag="PC592_003248"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDF4057180.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     NDALIDFELTSNRPDCKCMLGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRTAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITDD
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVADDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNVKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFVLKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEEVAKVHDKILSELSEKLNANLRSN"
     gene            7539..8129
                     /gene="zapA"
                     /locus_tag="PC592_003249"
     CDS             7539..8129
                     /gene="zapA"
                     /locus_tag="PC592_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDF4057181.1"
                     /translation="MNKVMVKIHGVEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAEAKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDVKNVE"
     gene            8328..9011
                     /locus_tag="PC592_003250"
     CDS             8328..9011
                     /locus_tag="PC592_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDF4057182.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKAKIHWRQVIIIIEMI
                     TILIVSFVPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFIFGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT         3486 a          988 c         1745 g         2821 t
ORIGIN      
        1 aaaaatatag atgtttttgg tgcaatttaa attaaaagat atatacaaaa atttaaaata
       61 ttccaaacag aaattataaa aattactatc attgtcttta tacaatattt atactataat
      121 agaataataa tttagaggaa agctctaaaa ataaacaaat taagggtctt aacagtagtg
      181 attttatgtt aaggaggtat aaagaaagtt gaaaacaata gttagaagac ttattctcta
      241 cgcagatgga atgcgtccta ctcaaataat ggtatctggg tttgctgcga ttattgtaat
      301 cggagcattg ttgttaacac tcccgatagc gtcgcagagt ggagagagta taggcttatt
      361 aaatgcttta tttacggcta cttcagcggt ttgtgttact ggtctagtta tggtagatac
      421 agcaacttat tggagtttat ttggacagat agttataata acattgatac aaattggtgg
      481 tcttggattt atgaccgtag ccacaatgtt ttcacttatg gcacgaaaaa aaatacaact
      541 aagagaaaga ttattaatac aggagtcatt aaatcaagct gatttatcgg ggcttgtaag
      601 acttacaaga tttgtattaa taataaccat aacaatagag ggaataggtg cactagtttt
      661 atcaactgtc tttattccac aatttggttt gtctagaggg atatggtata gtgtatttca
      721 cgcaatatca gcgttttgta atgccggatt tgacttgatg ggcagtgtaa gtggtccatt
      781 tacatcgtta aattcttatg taaacaactt tacagtatca atgactgttt gtgcacttat
      841 agtgcttgga gggctaggat tccctgttgt acttgatatt gtaggaaaaa gaagattttc
      901 aaaattaaat gtgcattcta aggttgtatt gttttcaact gcgacactta ttttagtggg
      961 tgcattattt atttttctta tagaatttaa tcaaaaagct actatggcgg acttgccttt
     1021 aaagggaaaa gtactatcag caatatttca atcagtaaca gcaagaactg ctggttttaa
     1081 tacgcttgat ttagccactt tacgagaaag tagtgtattt gtaatgataa ttttgatgtt
     1141 tattggagca tcacctgcat caactggtgg aggtataaaa acaactacac tagctgtttt
     1201 aatcattaca gttagaagtt ttctatcagg aaagtcagat atagaagctt ttgaaagaag
     1261 attagcacca gcaactataa aaaaatctct gggtatattt gtaattagta tatcagcagt
     1321 tatttttgga acattgatta tttcaataac tcaacctaat tttacattag ttcaatcggc
     1381 ttttgaggtt acatcagcac ttgctacagt tggttcaagt ttagctggaa ctccaaactt
     1441 aaatgcttta ggtaagatta taataataat ctttatgttt atgggtagag ttggttctct
     1501 tactttattt atggctatac tttctggtgg tagaagaaag agccaaccaa tcagatatgc
     1561 agaaggtaaa attatggttg gttaatttac caaggagtag tataaattta taatgggttt
     1621 agagtagtaa tgtaaatctg ttgataaaat aaatgagcct agatgtaatt atatgaagaa
     1681 ataaaatcga ctaatgagca aaattaatta atgaaataaa aaatagtgaa ataaaaaata
     1741 gtgaaataaa atacaaataa aagataaatc aaaattaaat taatctatgt atataaaatt
     1801 atagattgta tacaagtttt gtatgcataa ccgattaatt taatagatat tatataaatt
     1861 gtgtattagg gaggaagttt cgagatgaag caatatatag tcattgggtg tgggagattt
     1921 ggaagttcag ttgcgtctac tatgcatctt ttaggacatc aagtaatggc aatagacaaa
     1981 aatgaagatt cagttcaaag tatatctgac aaggtaaccc attcacttat agtggatgtt
     2041 actgatgagc aagcgttaag gtcattaggt ttaggtaact ttgatgtagc agtagttgca
     2101 ataggttctg atataagggc atctataatg gcgactctta tagccaaaga aatgggtgta
     2161 gagttgataa tatgtaaggc aaaggatgaa ttacaagcta aagtacttta taaaattggc
     2221 gcagatagag ttgtatttcc agaaagagat atgggagtaa gagttgcaca caatttagtt
     2281 tcagataata tattagacca tattgaactt gacccagagt attcaattgt tgaaatcgta
     2341 actccaaata gttgggttgg caagacactt atagagcttg aattaagagc tagatatgag
     2401 ataactgtac ttgctataaa aacaggtaaa aatataaatg ttacaccttc tccagatgag
     2461 gaacttacag ccggaagtat tctagttata attggtcaaa atactagtat aacagctata
     2521 acatctggaa ataaggggat aattagaaga agataattta ttatttaata tatatttaat
     2581 tgcaatgaaa gtagatagta tcatataatt atgaatagtt atatgatact atttttattt
     2641 aatcaaaagt aggatttaga tgtaagatta ggtaaagagt attttaagtt aaaaaaggag
     2701 taaggaggtt gtgctaatat agaaatttag catttagata aaatgattac gaatataaac
     2761 agtaaggata atgaaaaatt aaagtatacg aaagcactgt taaaatcaaa aaacaggaat
     2821 aaagaatcaa agttcataat agaaggttac agaatagtag tacttgcact tgaatgtatg
     2881 gcaaatcttg attatgtatt tatcaatgaa gattttgaaa ataagaaaga acatgtaaaa
     2941 ctattagaag atttagataa aaaaaacaca aagatatata agactactaa taaaaacttt
     3001 aaagaattag tggatacaga aaatactcaa ggtataatag gtgtagtttc atttaagaaa
     3061 aaaaaattaa gtgaaagtat aaataaaaaa gataaatttg tattgatttt agacagaata
     3121 caagacccag gaaatatggg gactataata aggactgctg attctgctgg ggtagaggcc
     3181 ataatagcac taaagggatg tgtcgatata tacaacccaa aagtaattag gtctactatg
     3241 ggttctattt ttgatatgaa tataattaat gcttcacaag atgaaactgt ggacatgctt
     3301 aaatcattgg attttaatat agtttcaagt tacttaaata cagataattt ttatgacaaa
     3361 atagattatg gttcaaaggt agcattggtg ataggaaatg aagcaaatgg aataaatgaa
     3421 gaacttgtat caaagtctga tattttggtt aagataccta tatatggtaa agctgagtca
     3481 ttaaatgctg cgataagctc tgctatactg atgtatgaaa taaaaaaatc cttaatttaa
     3541 tgtattgtaa taaatataat gtcatgttat aatcttgaat taaatagtag agtatcaaaa
     3601 atagtcaata tatattaaaa aaatagttca attaattata tattagatgt gtatcatata
     3661 aaaaatgatt gaatcaatta tatattagat gtatattata taaagaaata attgaattaa
     3721 ttatatatta gaggtatatt aaaaatagtc acataatttg aatggaaatg atataatact
     3781 aaaataaaca atatcatatt gtaaatgcaa tgaaagagga aagtattttg attaaactta
     3841 gtaaagagat aaacacctag gctgggagtg ttttctaaga ggtcacgaga agttccctct
     3901 ggagtaacag agctgaaatt ttatagtagg ctttgacgtc aaaaacgcgt taagtttgtt
     3961 agaggtggtt tgatgatttt taaattgtta aactactagg gtggtaccgc gaaactatag
     4021 cctttcgtcc ctagacaggg attgaagggc tttttttata caaaaaaacg aaagggtgat
     4081 atgtgtgcaa gaaaaattac ttgctttacg tgaagtagct ttggctgaaa taaaagaggc
     4141 acaaagcata gaaagtgtag aaagtttaag agttaagtac ttaggaaaaa aaggtgatat
     4201 aactgccata cttaaagaaa tgggtaaatt atcagccgag gaaagaccag tagttggtaa
     4261 ggttgccaat gaggtaagag aaaatattga acttagcata aattctaaaa aagaagaaat
     4321 aaatgctatt gaaaaagaaa gaaaattaaa agaagaagta atagatgtta ctcaaccagg
     4381 aaaagtttta aaggttggaa agaaacatcc aataactcaa attatagatg aagtaacaga
     4441 tatatttatc ggaatgggat tctctatagc agaaggtcca gaagttgaga ctgttgaaaa
     4501 caactttgat gctttaaatg ctcctaaaga ccatccatca agagatatga gcgacacatt
     4561 ctatatcaat gatggggtat tacttagaac tcaaacatct ccagttcaag taagaactat
     4621 gagaagtcaa gaattaccaa taaaagtaat tgcaccaggt agatgtttta ggtcagattc
     4681 accagatgcc acacactcac caatgttcca tcagatagaa gggcttgttg ttggaaaaga
     4741 tgttactatg gcagaattta aaggaactat ggatatcttc gttgaaaaat tgtttggttc
     4801 tgatatcaaa actaagttta gacctcataa cttcccattt acagagccaa gtgcagaggt
     4861 tgacgttact tgtttcaaat gtggtggtaa aggttgccca atgtgtaaat atgaaggttg
     4921 gatagaaata ttaggttcag gtatggttca tccaaacgtg cttagaaatt gtggaataga
     4981 cccagaagtt tatagcggat ttgcatttgg agttggggtt gaaagacttg caatgcttaa
     5041 atacgaaata gatgatatta gattattatt cgaaaatgat atgagattct taaatcaatt
     5101 ttaattagga gggtatgtag atgttagtat ctttaaaatg gcttagagac tatgttgata
     5161 tagacatgga tgtaaaagag ttcgctgata aaatgacaat gacaggaact aaagttgaga
     5221 caatagatta ttatggtgaa gaaatagaaa atatattggt tggaaagatt ttagaaataa
     5281 agcaacatcc aaatgctgat aagttggttg taactaaagt agatattgga gataaagttg
     5341 ttcaaatagt tacaggagct acaaatatat cagaaggaga ttatattcca gtagctgtaa
     5401 atggttctaa attacctgga ggagtggaaa tcaaacagac tgattttaga ggtgaattat
     5461 cagatggtat gatgtgttca gcagctgaac taggtataga tgaacattac attgaagagt
     5521 ataaaagagg tggtatatat attttagacc acgaagattc ttatgaatta ggaaaagata
     5581 taaaagatgt tttaggatta aatgacgctt taatagattt tgaattaact tcaaacagac
     5641 ctgattgtaa atgtatgctg ggtatagcta gagaagcagc tgcaactata ggaacaaaag
     5701 taaaatatcc tgaaattgaa gtaaaagaaa gtgatgaaga gatagacttc aaagttgaga
     5761 tagacaatcc agatttatgt agaagatatg ttgctagaat ggttacagat gtaaaaatag
     5821 aaccttctcc atattggatg caaagaagac ttacagaagc aggtgtaaga cctataagta
     5881 acatagtcga tataacaaac ttcgtaatgt tagagcttgg tcaaccactt catgcttttg
     5941 atataaatca agtagaaact ggaagaatag tagtaagaac tgctaaagat ggagaaaaac
     6001 ttgtaacatt agatgatgtt gagagaacat tagacaaaga tatgttagtt ataacaaatg
     6061 gagaaaaatc acttggttta gctggtgtaa tgggtggtgc taactcagaa ataactgatg
     6121 atacaaagac tgtacttttt gaaagtgcca atttcaaacc agaaaacata agaatgacag
     6181 ctaaaaaagt tggtattagg tcagaagcat cttcaagaaa tgaaaaagac ttagacccta
     6241 atcttgcaga gatagcagca aatagagctg cacaacttgt tgaaatgtta ggagcaggaa
     6301 aagttttaaa aggtgttgta gatgtatatc caaataaacc agaacctaaa aaattggtag
     6361 taaatcctca aagaattaac catttattag gtgtagatgt accaatggag cagtttgtag
     6421 gaatcttaga atcattagaa tttaaatgta atttagtagc tgatgataaa ttagaaatag
     6481 atgtaccaag ctttagaaca gatatggaac aagaagctga tgtatgggaa gaaatagcta
     6541 gaatttatgg atttgagaat ataccatctg tacaattaga aggaaatacg acagcaggaa
     6601 tcaaaacttc aaaacaaaag tttatggatg ctttaaaaga taattcaact gctgtaggac
     6661 taaatgaaat attaacatat tcatttgtaa gccctaaagg agtagataag ataagagtac
     6721 cagaaggtaa tgtgaagaga aattttgtta agctacttaa tccattagga gaagaaactt
     6781 ctgtaatgag aactacttta ataccaaata tgttagatgt tttatcaact aatgtatctc
     6841 ataaaataga agaagtatct gcatttgagt gtggacatat attcatccca caagattcag
     6901 aattacctaa ggaagaaaat agaatgtgtg taggtatgta cggtaaagat gttgatttct
     6961 ttgtactaaa aggaactata gaaactatac ttgtaaatgt aggatttaaa ggttatgaaa
     7021 ttgaacctca agataataat actaccttcc accctggtag atgtgctaaa atagtgtata
     7081 ataataaata tgtaggtaca ttaggtgaat tgcatccaga tgttatagaa aactacaatc
     7141 taggtcaaag agtttatgtc gctgaaatag atattgactt tgtatttgat aattctgata
     7201 gaacaaagaa ttatgtacca ttaccaaaat atccatctac atcaagagat atagctctta
     7261 ttgttaaaga tgatgtattt gtaaaacaga tagaagatat aataaaggaa aatggtcaag
     7321 gattagtaga aagctacaag ttatttgatg tttacaaagg ttctcaaata gaagctggat
     7381 acaagtcaat tgcatattca ataacttata gaagtaagga taaaactctg actgatgaag
     7441 aggtagctaa ggtgcatgat aagatattaa gtgaattaag cgaaaaattg aatgctaact
     7501 taagatcaaa ttaacaacta atgtcggggg aggttaggat gaacaaagta atggttaaaa
     7561 tccatggcgt tgaatatcca atggttggag acaaatcaga gaagtttatg attagtattg
     7621 ctgattttgt agacaaagaa atggataaaa taacacgtca aaacccgaaa ttgagcttat
     7681 cagttgctgc gatattgact gcattaaata tatcagacct tttatttgaa tgttcagatg
     7741 agaatgagaa gttgattaaa gctaatgaag aattgagtaa gaaggttgga gcatctaatg
     7801 aagagcttca attagaaatc aagtctttaa agcttacgat agcagaaaaa gaagcagaaa
     7861 atcgtgaagc tgaggctaag atgaaagagt taattgagat tatagaaaat aaaaagcaag
     7921 aaatattcga acttagtaat acgacagaag gttctagggc ggagttagat gcttataaaa
     7981 acaagattga ggagttaagt actcaacttg aagaagcaaa tgaaagagct accatagctg
     8041 aaaatttagc ttctgagttt caaaacaaag cttatgattt acagctaaaa tgtacagggt
     8101 taaataatga tgtaaaaaac gtggaataaa ttaaaagatt tgctgtctct tgttttttga
     8161 gacagcttct tttaatgtat aaatataaat gataaatata aataaatata aatgatgtat
     8221 aaatatagac aatatttaaa tataaatgat ttttttatat taatgaaaaa tagaatctaa
     8281 aatgattttg attttgtatc tatcattaga aagtgagagg tttatatatg acaagcaaga
     8341 gtcagatgtc cgaatcattc tttttatgtt ctttattggc aataacagga ggatttttag
     8401 atatttatac ttatgtggta agaggtaaag tatttgctaa tgcacaaact ggaaatatag
     8461 ttctatttgg gcttaatata gcagaaggta atgtaaagga atcattttat tatttgattc
     8521 ctattttggc atttatgtta ggcgtattta tagctgagaa gataagaaag tattttacaa
     8581 acaataaggc aaagattcat tggcgtcagg tcatcattat aattgaaatg attacaatac
     8641 ttattgtttc atttgttcct agaggaagat ttaatatgtt tgtaaatgtt gccatttctt
     8701 ttatttgttc aatgcaagtg gagagtttta gaaaggtaaa tgggaatagt tttgcaacga
     8761 caatgtgtac tggaaattta agaagtgcta cagaaacctt atttcattat atacatacta
     8821 agaatatttt tatgataaaa aagagtttac aatattatgc tattattata ttctttatat
     8881 ttggagctat tttaggaact ttttttacaa aaattttcgt ggaaaaatca atactaatat
     8941 gtttttttat tttggcagtg gtatttggaa ttatgtttat caataaagat gattcattta
     9001 atgaaaatta actttctgta aatttacaaa aaaatgaagc
//
LOCUS       DAMKOJ010000119         8952 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000119 DAMKOJ010000000
VERSION     DAMKOJ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8952
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.128"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(414..1310)
                     /locus_tag="PC592_003251"
     CDS             complement(414..1310)
                     /locus_tag="PC592_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057183.1"
                     /translation="MNDKNTYFDRKGKENFIDIFFKDDIKKGANFKRHWHEHLQVYYF
                     VDGIAYIECGLNNFKIVSGNIAIANSNELHYLESLSDNLKFYIIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSFILKCIKTILDEYHNKGIGYELSIKANIYQLIVL
                     LLRSHVDKIFSEDEFIERKYSLEKFEYIFDFIEEKYMDKITLKELASHVNLSVPHFCR
                     TFKKITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYDV
                     SPTKYRNEHREISNVILKEGIK"
     gene            1452..2879
                     /locus_tag="PC592_003252"
     CDS             1452..2879
                     /locus_tag="PC592_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4057184.1"
                     /translation="MTNSFKKDENKKRMIVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLSSIEWVIASYSIIICSTLLFFGRLGDIIDKSRVFQSGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKENRGKALGILVTAVAIGNMVGPSIGG
                     FILSIFDWNFIFFINIPIGIIVIFLNTKFLPNSKKSSENMNKTGAILQFLGTTLFFSA
                     LISAQQAGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQNTMKLAPIQAGSFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLFMSFGFFLMSRLKESSALILFVIYISIISMGQAIFQPANNALIMSSCYRSKL
                     GIVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYIINNDKIFVFGMRNVYT
                     IITLICLIGAILIGFYLFKYDKNKQ"
     gene            complement(3056..5650)
                     /gene="clpB"
                     /locus_tag="PC592_003253"
     CDS             complement(3056..5650)
                     /gene="clpB"
                     /locus_tag="PC592_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDF4057185.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSNRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETVIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5687..6283)
                     /locus_tag="PC592_003254"
     CDS             complement(5687..6283)
                     /locus_tag="PC592_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057186.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIVKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6300..6704)
                     /locus_tag="PC592_003255"
     CDS             complement(6300..6704)
                     /locus_tag="PC592_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HDF4057187.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            7071..7445
                     /locus_tag="PC592_003256"
     CDS             7071..7445
                     /locus_tag="PC592_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4057188.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7442..8305
                     /locus_tag="PC592_003257"
     CDS             7442..8305
                     /locus_tag="PC592_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057189.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWSDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHNPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8305..8943
                     /locus_tag="PC592_003258"
     CDS             8305..8943
                     /locus_tag="PC592_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF4057190.1"
                     /translation="MKGLILKDLLNLKGNVKFILLFIIMFGFMSSLGDGNINNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         3012 a         1327 c         1017 g         3596 t
ORIGIN      
        1 ggatgatttt tattataaaa ttttttataa acatataatt tttttatact catttgactt
       61 tcttttaatt ctttagagtg tatttaagtt ttctataaaa agcatactct tttagctgtt
      121 tacttactta tttgatagtt ttgtttcttt aattaaatat ctttcagaat ctaagctaga
      181 tgtctcaaaa aaaacagatt tgtaatataa ttattttttc tgctattcct atttttccaa
      241 ccttagtttc atagtaaagt acacttttca tatacactac attctttcat actcattttc
      301 aaatttaact acacaaatag tcttactcat ttatatccta tactttatta atgtttatta
      361 agaaaaactc aaagatttaa aaatatatat tttctataaa gtatatttat gaattattta
      421 ataccttctt ttaaaataac attactaatt tctctatgtt catttctata cttagttgga
      481 gatacatcat aattcctttt aaataagcga ctaaaataat ttatgctatc aaagccgcat
      541 ctcatagcaa tttctgtcat atttaaatct gtttccttta aataatatat agctttatca
      601 agtctgattc catttataaa atcgattgta gtcttacctg ttattttctt aaatgttcta
      661 caaaaatgag gcacactcaa gtttacatga ctagcaagtt cttttaatgt aattttatcc
      721 atatattttt cttctataaa atcaaatata tattcaaatt tttctaaaga atactttctc
      781 tctataaatt catcttcaga aaatatttta tcaacatgac ttcttagtaa taatactatc
      841 aattgataga tattagcttt tatagatagc tcatatccaa ttcctttatt gtgatattcg
      901 tcaagtatag ttttaataca ttttaaaata aaagaatcat tttgaattaa attattaaat
      961 acaatatgat ttaaagctaa tggtgctaag tacttagttt gtaacaaatc aacttgatta
     1021 ctaaaaagga atgtgggttc aattcgaata atatagaatt ttaaattatc tgataaactt
     1081 tctaaataat gcaattcatt actatttgct attgcaatat ttccagatac tatcttaaaa
     1141 ttattcaatc cacattcaat ataggctata ccatcaacaa aataatatac ttgtaaatgc
     1201 tcatgccaat gtcttttaaa atttgctccc tttttaatgt catccttaaa aaaaatatct
     1261 ataaagtttt ctttaccttt cctgtcaaaa tatgtgtttt tatcattcat tatttacctc
     1321 ttatcaaaat agtgctaatt atgagcaata tcgttattgt attcattatt tcataccgat
     1381 attatataag atgtgactat tattgtaaac attaacatga tgccagtcat tataataagg
     1441 aggtaataaa aatgacaaac tcttttaaaa aagatgaaaa taaaaaaaga atgatagttt
     1501 tatttgtagt cattgcaatg acctttatgg caacattaga ttctagtatt ataaatgttg
     1561 ctcttccagt tcttgcaagc aaactaaatg tatctctatc atctattgaa tgggtaatag
     1621 caagttactc gattattatt tgttcaacac tattattttt tggaagactt ggggatatta
     1681 ttgataaatc cagagtattt caatcaggta ctattctttt tacatcagct tcattattat
     1741 gtggattaag taattcttta actttactta tagtttgtcg ctttattcaa gggataggtg
     1801 cttctgccta catggcaaac aatcatggta ttatcacaga actgtttcca aaagaaaaca
     1861 gaggaaaggc actaggaatt ttagttactg cagttgctat tggaaatatg gttggaccat
     1921 ctataggagg atttattttg tcaatatttg attggaattt tatattcttt ataaatattc
     1981 caatcggtat tattgtaatc tttttaaata caaaatttct tcctaatagt aaaaaatctt
     2041 cagaaaatat gaataagact ggtgctatac ttcaattttt aggaacaaca ttatttttta
     2101 gtgctctaat tagtgctcaa caagcaggat tactaaatcc atatatatta attgcactat
     2161 tattatcaat tatttttatt atattatttt tgatattaga aaaaaaacat cctcaaccgc
     2221 ttcttgacct tgaaattttt agaaatttta aattttcatt gaatttaatt tgcgctctta
     2281 catcattcat ttgtattgca tcatctagta ttttaattcc attttattta caaaatacta
     2341 tgaaacttgc ccctattcaa gcaggttcat ttatgatatt atcacctttg attttagcca
     2401 ttttttcacc tatatttggg aatatatcag ataaaattaa gtcagaaaaa attattttaa
     2461 ttggtcttct ctttatgagt tttggatttt ttctaatgtc aagattaaaa gaaagttctg
     2521 cccttatttt atttgtaatt tatatatcga taatatcaat gggacaagct atatttcaac
     2581 ctgctaacaa tgctttgata atgtcaagct gttatagaag taagttagga attgtaggaa
     2641 gcataaattc ccttgtaaga aatttaggac aagttatagg tattactatt tctacaacac
     2701 ttttatataa ttttatgagt attaaagctg gatatagggt caatgattat ataattaata
     2761 atgataaaat atttgtattt ggaatgagaa atgtttatac tattattaca cttatttgcc
     2821 taataggtgc aatattaatt ggcttttatt tatttaaata tgataaaaat aaacaatagt
     2881 ttttttataa ttgtattcaa accattatta tattataaga aacttactaa aatactccct
     2941 ttgagttaaa tttaatttga acacattggc ttaaaaatat ttcttttcct atagtttata
     3001 aataaaaatc agctgagcaa aatatttcat atactatgct cagctgattc tcttattatt
     3061 taactaaaac ttcaatattt tcatcttttc catctataac tatagtacat ccattataca
     3121 catctccagc aataagtttc tttgcaatta cagtttctaa tgtatttcct atatatctct
     3181 taagaggtct tgctccgtat acagggtcat atccctctct caccataaca tcttttgctg
     3241 aatttgtaac ttcaatagta atatcttttt cttttaatct attttttaaa tctttcataa
     3301 atatatctat aattttcttg atattttctt ggtctaaagg cttaaacatt ataatatcat
     3361 ctactctatt taaaaactca ggtttaaatc tatgcttcat ttcattcatt actaaattat
     3421 tagtagtctc tgttatattc cctcctgctt ctaatagata attacttcct atattagaag
     3481 tcattattat aagagtattt ttaaagtcta ctgtcttacc cttattatca gtaagcctac
     3541 catcatctaa tatctgtaag aacatgttaa atacatcctc atgtgctttt tctatctcat
     3601 caaataatat tacagaataa ggagcacgtc taactgcttc tgtaagttga ccaccttctt
     3661 catatcccac ataccctgga ggaggcccaa ctagtcttga tacagcatgt ttttccatgt
     3721 actcagacat atcaattctg attatattat cttcactatc aaataaattt ctagcaagag
     3781 tttttgcaag ctcagtttta ccaacacctg taggacctaa gaaaataaat gaaccaattg
     3841 gttttctttc atcttttaat cccgctcttg cacgtattac tgcatttgaa actgctgtaa
     3901 ctgcttcatc ttgtccaata actcttttat gaagttcatc ttctagttta agtaattttt
     3961 ctctttctcc ttcaactagt ttagttactg gtatacctgt ccactttgat acaatgctag
     4021 atatttcctc ttcagtaact tcttctttta aaagagaatt ttcagaacca tcgttcatat
     4081 tttcttcgta ctgctttatt tgttcttcta acttaggtat ttcaccatat ttaacctctg
     4141 ctgctttatt aaaatcatat tctctctcat atttttcagc tttaccttta gcttcgtcta
     4201 attgagcctt taagttttta atatctaata tttgactctt ttccttttca tattttgctg
     4261 tcatttcatc atttttagat tttaactctg ctatttcttt ttgaatatca tccaatcttg
     4321 atttactttt atcatcattt tctttaagta atgcttccct ttcagtttcc aatgtaaata
     4381 attttcttct aacaacatct aactctgttg gtaatgaatc tatttcgcta cgaatcatag
     4441 ctccagcttc atcaattaag tcaattgctt tatctggtaa aaatctatct tgtatatatc
     4501 tattagaaag ttttgctgcc gctacaatag cattatcatg tattcttact ccatggtgta
     4561 tctcaaatct ttcttttaaa cctctaagta tagatattgt atcttcaaca gtaggttcct
     4621 ctgcaattac aggttgaaaa cgtctctcaa gagccttatc tttttctata tactttctat
     4681 attcatcaaa agtagttgca ccaatacagt ttaattcacc tcttgcaagc ataggcttaa
     4741 taagattgcc tgcatccatt gagccttctg ttttaccagc tccaactata gtatgaatct
     4801 catctataaa tagtataatt tttccatcag aactttgaac ttcttttaag actgccttta
     4861 atctttcttc aaattcacct ctatattttg caccagcaat taaagcaccc atatcaagtg
     4921 agaatacaat tttatctttt aaaccttctg ggacatctcc tcttacaatt ctctctgcta
     4981 aaccttctac aattgcagtt ttacctacac caggctcacc aattagcaca ggattatttt
     5041 tagttcttct tgataaaatt cttataattc ttcttatttc ttcatctctt ccaattacag
     5101 ggtctaattt atttttcttg gctaaatcta ctaagtttgt tccatatcta gcaagtgcat
     5161 catatgttcc ttctgggtct tgtgtttcta ctctttgact acctctcact tgtgataaaa
     5221 tgtttaaaaa gtcattctta tttatattat attgctttaa tattttacca acagctgatt
     5281 ttgattctgt ttccatcatt gcaagcataa catgttctac acttatatat gagtctttaa
     5341 attctttaga aatgctctct gcctttataa gcacctcatt tatttttcta gtggctgata
     5401 ctccttgtga gtcagctcct tctccatata cttttggaag cttatcaatt tcaaagttta
     5461 cagtatttct caaagaatca attgatatat tcattttttc gattatattt ggtattaatc
     5521 catcttcttg attaataagt gctgagaaaa gatgaattac atctacttgt tggttatgat
     5581 tttttactgc ttcattataa gcctcattta aacttttttg aactcttaaa gtcatttttt
     5641 ctacgtccat ataaatccct ccattttaat attatatcca aataaattaa attctctcat
     5701 ttataattat tgattttcta agctctaaaa gactatcaag taaattctca tttttttgta
     5761 tatcgaaact caaagttaaa ttaaatgttc catctgaatt aaaaaaatca aatacttctt
     5821 ttgattttac tattaaatac aaatcttcat ctataagtct tttttcacct attaataaat
     5881 actgacattt atctataaag ctctttttaa aatcaatagt gtatagattt tctaaaatat
     5941 tatattgata aatggcaata ttgttaaaca cttttaatat gtttgaattt acaaaattgt
     6001 aaatttgatt attgttatac agtgatattt gttcgtatat atattcccta aataaaggat
     6061 gaatgttttg cttaagtttt aaagtaactt cagctggtat ttcaaaataa agcttccagt
     6121 acttagagtt atttttttct aaaataaaag ctactttatt aagactggta gaactaatct
     6181 cctttagtgt acaattaaaa ttatagtgtc tcaaactagt tttttcattc tcaaatacat
     6241 aatcaaacca ctgtagaaca tttctatcaa gttttaaact catataaaaa ccttcttcct
     6301 tatttactaa ccttattagg tctttttatc tgattatatt ctgctaataa actttcttta
     6361 tcagctctac tacctttata tgctatatgt ggatttatca tatactcacc atttttcact
     6421 ctttgtaaaa aatccatttt tttcagctcc gtaaacaatg aagataaaga agtttttgga
     6481 tattcaaatt cacaagataa ttcatataat gtttttctaa tcttattatt tttatccata
     6541 gagtttatta attttaatgg aattaaatcc ctcttagtat acattccttc tactacttta
     6601 atataattct taaaacaaac attcatatac ttacttttat tcataactaa acttttactc
     6661 tctgtgtatt cctgatttaa atcctttttt aatgtcttat ccaaattaaa tatctcttct
     6721 cactctcctt atctctaatt gataatataa atatattaca aaaaaatatg tatgtcaaaa
     6781 ctgaaaacac aaaaagttta gcttataaat aaacttttat ttacctataa gctaaacttt
     6841 attatttttt taatttagta tttccaattt attggcagga tttttgaata atatttataa
     6901 attttttaaa aaaatttaaa tctatttaat atggtagcct ttcataaaat acattacatt
     6961 tattaaatgt ataatattgg caattagttt tttctaaaat cagttgacat attatatata
     7021 tatttatata atgtgtatat actatatata caatttaagg aggtgtctta ttgaatatag
     7081 ttattagtaa ttcgagtggg aagccaatat atgaacagat tactacacaa attaaaagta
     7141 tgattataag tggagaatta ccagaaggct cagctcttcc aagcatgaga ctattggcaa
     7201 aagaacttag aataagtgta attactacaa aacgagcata tagcgattta gaacgagacg
     7261 gatttattga gacagttact ggtaaaggca gttttgtatc tagtaaaaac atggattttg
     7321 tcaaagaaga acaatttcgt ttaattgaag aatacctaca gaaagcagtt gatacagcaa
     7381 aaagtagtga tattacatat gacgaattaa aagatatttt atttttatta tataaaggag
     7441 aatgataagt atggatgcaa taactataaa aaatttaaat aaaacttata aagattttag
     7501 cctacaagat atatcttttt cagtaccaaa agggagtgta atgggatttg taggtgaaaa
     7561 tggtgcagga aaaacaacta cattaaaagc aattttaaat ttaatatctt atgatagtgg
     7621 aaatatagaa atctttggtc ttgatagtaa aaaaaatgaa aaagaaatta aagagcaaat
     7681 tggggttgta tttgagggaa gcaactttca tgaaaattta aacactgacc atgtttcaaa
     7741 aatcatgagt aaaatctata aaaattggag tgacacatta tttaaagact acttaaaaaa
     7801 attgagagta ccagacaata aattaattaa ggagttttca aaggggaata agatgaaact
     7861 tagtattgct gtagccttat ctcataaccc aaaattatta atactagatg aggcaactag
     7921 ttcacttgac cctatcgttc gtgaagaaat actagatata tttttagatt ttatacaaga
     7981 tgaagaacac tctattatct tatcttcaca tattacaagt gatttagata agatagcaga
     8041 ctatattaca tttatacata aaggaaaaat tgtatttagt gaaaataagg atgaattaat
     8101 tgatactatg ggagttttaa aatgtaaacc tagtgatttt gataaccttt caagagagga
     8161 ttattcatat tatcgtaaaa gccaatttgg atatgaagta cttcttaaag ataagcatag
     8221 atttatctca agacatccaa actgtattgt tgataataca tctatagaag aaattatgtt
     8281 attttatgtg agaggtgata aataatgaaa ggtctaattt taaaagattt acttaatttg
     8341 aaaggaaatg taaagtttat acttttattc atcattatgt ttggttttat gtcttcttta
     8401 ggagatggaa atattaataa ctttataggt gttattatag ttttatgtac tacaatgatt
     8461 gtttcaacat tttcatatga tgatttaaat aaatgggata gttatgtact tacaatgcct
     8521 attaatcgca atgatattgt attaagtaaa tatttaacta tgttaatatt tagcttcata
     8581 ggtgttctcg tttcacttat tgttagtgta actattggtt attttaaaaa tacacttata
     8641 ttaaatgaaa cactacttat taatgcacta atcttatcaa tttcagtatg ttttggtagc
     8701 cttattttgc cacttattta taaatttggt acagaaagag ctcgtttatt aatgatttta
     8761 tgctttttag ttccaacact agctttatta gtttttaaaa gtattttaga aaatattagt
     8821 tcacctattt ctatagaaat tatacttaat acactagtat attctcttcc atttgttgct
     8881 attttactat ttgtgatttc atattttata tcatcaaaaa tctatagtaa aaaagaagta
     8941 taaaatatac ta
//
LOCUS       DAMKOJ010000120         8886 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000120 DAMKOJ010000000
VERSION     DAMKOJ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8886
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.129"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(62..586)
                     /locus_tag="PC592_003259"
     CDS             complement(62..586)
                     /locus_tag="PC592_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF4057191.1"
                     /translation="MKSIVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFFKKNYKELQKKNLVVFGVGAAPYDDEVIKRLREVNFKDE
                     LNKVPCFYCRGAWDETKMSFLDYTLCSFFKKSIAKKERQGLKPVEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            complement(635..1132)
                     /locus_tag="PC592_003260"
     CDS             complement(635..1132)
                     /locus_tag="PC592_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4057192.1"
                     /translation="MNVETLMKKFMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKGRVEEYSKKVRGIQEKVLQLLFKDFTEKEVEQLFFGIMKLSAGIENVKNYVEN
                     NDIEE"
     gene            complement(1365..2642)
                     /gene="hflX"
                     /locus_tag="PC592_003261"
     CDS             complement(1365..2642)
                     /gene="hflX"
                     /locus_tag="PC592_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF4057193.1"
                     /translation="MDMAKKGITAGLNINNKSEDFNELMIELGNLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEELLNLIKKESIEVVVFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLVGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITFLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIILANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKNHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DEILDSIDKEGLFVSVKKDINIDKMIKCICDSIFKDYVRCKLLIPYDKGHVVSYFNEN
                     ASVISTEYREDGVILDVECSNIEYNKYKKYVLE"
     gene            complement(3371..5203)
                     /locus_tag="PC592_003262"
     CDS             complement(3371..5203)
                     /locus_tag="PC592_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057194.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILMFLLCLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISEKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAILILPISMFVISRIVKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEDQIVENAVSIDGLKGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYNMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(5196..7442)
                     /locus_tag="PC592_003263"
     CDS             complement(5196..7442)
                     /locus_tag="PC592_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057195.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELDKITLFMDKSSKDKVLDNYTLLNEKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNIIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFEGMPESMITQSSVSYVKSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMVSMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEEQEFKVDKKGLVEFRNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKEATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(7510..7971)
                     /locus_tag="PC592_003264"
     CDS             complement(7510..7971)
                     /locus_tag="PC592_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF4057196.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNRVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEEEKYF"
     gene            complement(8276..8842)
                     /locus_tag="PC592_003265"
     CDS             complement(8276..8842)
                     /locus_tag="PC592_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HDF4057197.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT         2866 a         1617 c          881 g         3522 t
ORIGIN      
        1 tgtctaataa atttctatgg aatttaactt tagataataa ataattataa atatatacct
       61 cttaaagttc tcttatataa tcgagtattg gagttaaatt ttctttatta caccaatcaa
      121 atgcttctcc agacaataaa ggtgcttcta ctggtttaag accttgacgt tctttttttg
      181 ctatagattt tttaaaaaaa ctacaaagag tataatctag aaaagacatt tttgtctcat
      241 cccatgcccc acgacaataa aagcaaggaa ctttgtttaa ttcatcctta aagtttactt
      301 ctcttaatct ctttattact tcatcatcat atggagcagc tcctacacca aatactacta
      361 gatttttttt ctgtaattct ttataatttt ttttaaagaa agaaattcct gctatgttac
      421 aagcataaag acctcctcct aaaataatcg tatcatactt cataaccttt tctatattaa
      481 tattcttagt ttcaaaaata tcacaagaca ataattctga aagccactta gcatattttt
      541 ttgttgaacc atatttactc ttataaatca ctactatact tttcatataa attatctcct
      601 ttctgatgtc atacaaagtt gattcgacac ttgcttattc ttcaatgtca ttattttcta
      661 cataattttt cacattttca attcctgcac ttaatttcat aattccaaaa aataactgtt
      721 ccacttcttt ctctgtaaaa tctttaaata aaagctgtaa tactttttct tgaatacccc
      781 ttactttttt agaatactct tccactctac cttttgtcac aagacagata gctcgtgaat
      841 ctttttcatt ttgctcaatt tgtataaaac ccttcttttc taaagcaata gctagttttt
      901 ttacattttg tcttgagcac cccattaatt ctccaagttt agttaatgta agagtttcat
      961 ctacagagtc cgcaatagct aaaagtaacc attgtttcat agttaattct gggtctaatt
     1021 tatcacatgt agtttgaagt ttattttgca ttacaaatat acttgcaaat atagcttgtt
     1081 ttctactatc atcatctacc ataaattttt tcattaaagt ttctacattc attattatac
     1141 acttctcttt atcttagatt ttaatttttt gataacttta aatagtaact agttacttta
     1201 tattatagta attggttact attatgtcaa caaatttatt tttatcataa atggtaaaac
     1261 ggcatagctt gtggctatac cgtttcataa aatcatattt tacaatcaat ttataattaa
     1321 ttataaatta aatatatttt aagctataat aattttttca aaatttactc taaaacatac
     1381 tttttatact tattatattc tatattgcta cattctacat ctaaaataac tccatcttct
     1441 ctatattctg tacttataac gctcgcattt tcgttaaagt aagaaactac atgcccttta
     1501 tcatatggaa ttaaaagttt acatcttaca taatctttaa atatactatc acaaatacat
     1561 tttatcattt tatctatatt tatatctttt ttaactgaaa caaataaacc ttctttatcg
     1621 atactatcta aaatttcatc taatacttct acatctatta aatcaatttt attatacaca
     1681 tgtatcatag gtataccatc tgcaccgatt tgttttaaag tatcttctgt cactttaata
     1741 tgatttttat agcttggatt tgaaatatca ataacatgta gcagtacatc tgcctcacat
     1801 gcttcttcta atgttgacct aaatgctttt actaaatcat gtggtaaatt acttacaaac
     1861 ccaacagtat cagataataa aaattctttg ttatttgcaa gaattatatt tctaacagaa
     1921 gtttcaagtg tagcaaataa catgtttttc tcaaatactt tcttttcttc agagttttta
     1981 aatatatcta ctaatttgtt cattattgaa gatttaccag catttgtata cccaactaaa
     2041 gctacatttg gaagatttga ttttcttctc atacttcttt gagtttctct ttggaatttt
     2101 aagtcatcta actccctatt tagaaatgtt atcttttctt ctattcttct acggtcaagt
     2161 tctaattttt tctcaccaga gcctctattt ttagtaccaa ctccaccact ttgacgccct
     2221 aaattttcat ttgaacctac aagtctaggt aacatatatt ttaaacttgc tacttctact
     2281 tgaagtttag cttctctagt ttttgccctt tgtgcaaata tatcaagtat caatgctgtt
     2341 ctatctataa tttcacaatt gagcttttct tcaagatttt ttagttgtga tgtagaaagt
     2401 tcattgtaaa atacaactac ctctatgctt tctttcttta ttaagtttaa taattcctca
     2461 actttacctg tcccaatgta aaatgctcta ttaacctgct ttgcattttg agttatactc
     2521 ccaacaacat caatatcaca tgctgaacat aagtttccaa gttcaatcat tagttcatta
     2581 aagtcctcag atttattatt tatatttagt cctgctgtta ttcctttttt cgccatatcc
     2641 atattctcct tatctgctat tttttattta atctatagca caagattatg gctctataat
     2701 taaattcatc aagaatttta ttttttatct tatccttaaa tgacacttat taaattataa
     2761 attttaccat tataataacc ataatcgtgc attattttct caatcttata taaaaaatca
     2821 ctttcttaca cctcctccta aatatattat gcagtttttt caataaaaaa actccttaca
     2881 aatctaagta atacaaaaca agctacttat atcataagaa ggattaaagt tctaaatata
     2941 tattaaaaat acattagttt aattaacttg tatgtaatta tcattttata tttaacccta
     3001 ttcttaaatt taagtagtta tttacatgat taataaaagc aataaaaata tctacttcaa
     3061 tataatcatc aactattaaa attaaatttt atttataata aaatttaaag aatataatta
     3121 aatatacatt ttgataatca cctccaacat tttccttact acatattata ataaaattaa
     3181 aacgttgtaa agacataaaa ttgtgtagat gtctcaaaat aaatagaatc ctctttttta
     3241 ttgctaaaat gataaaaata cattttgttt catacataaa agagtgcctt atgaaccaaa
     3301 aagttcattt taagacactc tcatttattt tatcttatta attaaacttc tatgctaaga
     3361 tagttttttg ttacattgct tcatcttctt caaattgaga attgtaaaga ttagcataaa
     3421 atccaccttt ctttagaagt tcctcatgat ttccttgttc aactatatct ccttcattca
     3481 ttacaagaat catatcagca tcacgtatag ttgataatct gtgggctata acaaaacttg
     3541 ttctaccttc cataagatta tccatagcct tttgaatcaa tacttctgtt ctagtatcaa
     3601 cagaacttgt agcttcatct aatattaaaa ttttaggatc agctaaaata gcacgagcta
     3661 tagtcaataa ttgtttttga ccttgagaaa cattacttgc ttcttcattt aatttcatat
     3721 tatatccatc tggtaatgtc ttaataaatc tatgaacatg tgcagattta gcagcctcta
     3781 taacttcttc atctgtagca ttcaacttac catatcttat attttccata attgaaccac
     3841 taaataacca tgtatcttga agaaccatac caaacatttc tctaagctca ctacgattaa
     3901 aatctttaat attatgtcca tcaatcagta ttgaaccgct attaacatca taaaatctca
     3961 ttaaaagttt aactattgta gttttacctg ctcctgtagg tccaacaata gcaacttttt
     4021 gaccaggttt aacatttact gaaaaatcat ttattatagt cttgtttggg ttatatccaa
     4081 agttaacatt ttcaaaatca attttacctt ttaaaccatc tattgaaact gcattttcaa
     4141 caatttggtc ttcttcttcc tcttctaaaa actcaaatac tctttcagaa gctgctgctg
     4201 ttgattgcaa taaattggca acctgtgcaa tctgagtcat tggctgtgta aagtttctta
     4261 catattgtat aaatgattgt atgtcaccaa cctcaattgt tttcttaatt gcaagccaac
     4321 ctcctaagat tgataccatt acatatccca agtttccaat aaacatcata agtggttgca
     4381 ttatacctga taaaaattga gacttccatg ctgaattata caggctatca tttaatttat
     4441 caaactcttc aattacctca tcttcacgat taaatgcttt cactattgtt tgaccactat
     4501 aagtttcttc aacttgacca tttacatttc ctaaatattc ttgttgatat ctaaagtatt
     4561 tttgtgattt ctttactatt cttgaaatta caaacattga tattggtaat attaaaattg
     4621 ctaccaatgt cataattcca cttatagata acatcattat caaaacacct atcatagttg
     4681 ttactgatgt tataagctgt gtcatacttt gatttaaact ttgatttaaa gtatctatat
     4741 cattcgtaat tctcgataat atttcaccat gcgtcttagt atcaaaatac ttcattggca
     4801 atctatccaa tttttctgaa atctcttttc ttaaattata ggatactttt tgagaaattc
     4861 cactcattat aaatccttgt ataaaagaga acagtgcact tattaaataa aggcaaagta
     4921 aaaacattaa gatttttcca attgcattaa aatctatacc tacatttcct ccagaaactt
     4981 tactcactaa tccttcaaat atctttgtag ttgccttacc taaaattttt ggacctacta
     5041 tagaaaacga cgcactacca atagcaaata caattactaa aattattgat attttaaatt
     5101 tagataagta tgcaattagt tttctcatag tccctttaaa gtcatttgct ttttgtcctg
     5161 ctcccataga ttttcccata ggacctcttc ccattctact cattagctag ctcctccttt
     5221 gaaagttgtg ataaagctat ttgctcataa acttcgcaat tttttagaag ctctttatgt
     5281 gttcctattc caactatttc tccctcattt aaaacaatta tctgttctgc atttaagata
     5341 gtactaattc tttgtgcaac tattaaaact gtactttcag cagtttttga ttttaaagcc
     5401 ttacgaagag ctgcatcagt ttttaagtca agtgctgaaa aactatcatc aaatatataa
     5461 acttctggat tttttgctat tgcccttgca atagaaagtc tttgtttttg acctccagat
     5521 acatttgttc caccttgaga aatttcagtt ttaaaagctt ctggtttaga atctataaat
     5581 tctgtagctt gagctatttc agctgctgtt ctcatttctt catctgttgc ttcttttcta
     5641 ccatatttta aattggattc tatagtacca gaaaacaata ctcccttttg aggtacatat
     5701 ccaatttttt ctcttaaatc atgctgagaa acatttttta tattaactcc accaagtaag
     5761 atttctcctt cagtaacatc aaagaaacga ggaattaaat ttataagagt tgacttacca
     5821 ctaccagtac ttcctataaa agcagttgtt tctcctggct ttgctgtaaa agatatattt
     5881 gttaatatag gttcctctgc gtctggatac atgaatgaaa catttctaaa ttcaacaaga
     5941 ccctttttat ctaccttaaa ttcttgttcc tctgattttt ctgggtcttt tatgcttata
     6001 tctgacacta gtacttcatc tatacgtgta gctgaaacgg atgctcttgg aagcatgata
     6061 gataccattg atatcattaa gaatgacatt attatttgca ttgtatattg tataaatgcc
     6121 atcatatctc caacttgcat tgctccagaa tcaacactat atgcacctct ccaaactata
     6181 agaactgtga taaggttcat tataagcatc atagccggca tcatacatgt cataactcta
     6241 tttacaaaaa gatttgtttt agttaaattt ttatttgctt tatcaaatct ttcttcttca
     6301 tgtttttcag tactaaaagc tctgataact ggaataccag taattatttc acgacttact
     6361 aagtttaact tatctacaag cttttgaact agtttaaact taggcataac cactgagaat
     6421 aacactacaa ttaatgataa aatagcaact actgctactg ctataatcca tgccattgaa
     6481 gtatttgtgt ttaaaacttt tattactcca cctatagcca ttataggtgc atagaatact
     6541 attctaagca acataaccat caacatttgt atctgttgaa tatcatttgt actacgagta
     6601 attaatgaag ctgtagaaaa ttcattcatt tcagtatttg aaaatgacat aacttttcta
     6661 aagactccac ttcttaaatt tctacctaca cttgctgcta ctcttgctgc taaaaatcct
     6721 actgttattg tggctaccat actaaccatt gctataccaa gcattttagc cccagtaaat
     6781 aatatataat tattttgagt tttttctgta tcaataccta ttttctcata ttctgacttt
     6841 acatatgata ctgaactttg tgttatcata ctctctggca taccttcaaa gcctttgctc
     6901 atctctttag tcaatgtgtc taactgttcc tttggcattg ctgatagcaa tttaaatata
     6961 tcaacatctc cactttgagt agcttgtggt ggaagtttac tcattaactg agctttcata
     7021 gcttttacct ctttactatc gccctcaagc cctgatacta tcaaaatagc cttaccaaaa
     7081 ataatattta aatcatctat agtatctttg tctttagtat ttaactcata aagagattca
     7141 tcttttagac ctgggtactt atctttatac ttaacataat ccttttcatt caacaaagta
     7201 taattatcta gtactttgtc cttactgctt ttatccataa ataaagtaat tttatctaat
     7261 tcactctctc taatcacaga tggaacagag ttttctactc caccttgttg tatacctaca
     7321 tttactatat tggatgtgta ttctggtaaa gaaaggtcac ataccgcttg aattaccaat
     7381 aggcagacta ttattactat tgataatgcc gatttcttta aatatttaat taatttaaac
     7441 atacatttct tcccttctgt aatattaatt agtctaataa cattaaattg aaaaatatta
     7501 ttttaaactt taaaaatatt tttcttcttc atgcttatga catcctgctt ttaaattatc
     7561 tcgtacttgc attagaagtc ttctaagtac tattttttct tcttcactaa atcctaaaaa
     7621 aaactctctt tccaattcct tgttaaattc ttcaactcta ttacatattt ctaaaccttt
     7681 gtctgtcaaa aaaattctag atactctttg gtccttttca tcttgttttc tttccacaag
     7741 tccagctttt tccatcctct ttatcataac tgtagttgta gatgctttta ctttcctttt
     7801 atctgctaat tctttttgac tttgcccatc tttcatcttt aaagaaaaaa gtatttgagg
     7861 ttgaccatga tataagccta atttatcaaa ataaaaatga gttcttataa aatatattcg
     7921 cattaattgc aagaaaacat catttaattt ttcttcagaa ttgctattca tacttgccct
     7981 ccttattttt tatattactt agtcggctaa gcattatttt actatactgc atgcattttt
     8041 tcaatatatt tataaaaaat tcatataaat ttcatttatt aaatattttc acatcatata
     8101 gttatacttt taataaataa tagtaagatt tttaattagt cagctacgta tattttttat
     8161 tgcaaagctt aaaataaacc ttttcatata ttttcaaata aaaaagttgt cccaaaataa
     8221 attttgaaac aacatcttac tcaacagtat cttgattata taacactata atactctatt
     8281 tatcttcata tccatttaca acaacatcta attttccagt ttctggtgat ataattagac
     8341 catgtacaat aataccatct ggaattaaag gatgcccttt tattaaatca atactatctt
     8401 ttacagattc ttctgcagaa tcgaatccat gtaaccattg ttttgtatca attccagcac
     8461 tacgaagtgt aagtattaca tcattagata ttcctctatc taaaatttta ccaagtaact
     8521 tatccgtatc aacattacac ataccacatc catgatgccc tacaaccatg acctcatcta
     8581 catcaaattc gtaaattgca actaaaacac ttctcataat acttccaaaa ggatgcatta
     8641 tagtagctcc tgcatttttt attagtttca catctccatt ttttaaattc atagccttag
     8701 gcaaaagctc agttaatctt gtatccatac aagataagac tactattttt ttatttggat
     8761 gttttgatgt cacatattgt tcatattctt tgttctctac aaatgattta ttatactcta
     8821 atatctcctc aagttttctc atatgtaata tcaccctctt taaaaatttt tttattatta
     8881 tatcac
//
LOCUS       DAMKOJ010000121         8666 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000121 DAMKOJ010000000
VERSION     DAMKOJ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.130"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     misc_binding    109..320
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            483..1772
                     /locus_tag="PC592_003266"
     CDS             483..1772
                     /locus_tag="PC592_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF4057198.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGIPVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIVATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSMKNNQEIDKAV"
     gene            1826..2905
                     /locus_tag="PC592_003267"
     CDS             1826..2905
                     /locus_tag="PC592_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HDF4057199.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     SKSDSKGAVENILKELSGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2926..4470
                     /locus_tag="PC592_003268"
     CDS             2926..4470
                     /locus_tag="PC592_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDF4057200.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKDKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGNTLTLSDIVTKLDMAFEDRKSNVENLDKEYCDEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            4585..4776
                     /locus_tag="PC592_003269"
                     /pseudo
     CDS             4585..4776
                     /locus_tag="PC592_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5029..5571)
                     /locus_tag="PC592_003270"
     CDS             complement(5029..5571)
                     /locus_tag="PC592_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HDF4057201.1"
                     /translation="MKRYIALLRGINISGKNKIVMSELKAGFVELGYSAVSTYLNSGN
                     VVFLSNVDDSEVISNSIGLMIKKQFELEIPVFIISQEVLEDILNNAPSWWGDNNKEIY
                     DNLIFMFPDLSYDKFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYQKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(6020..6304)
                     /locus_tag="PC592_003271"
     CDS             complement(6020..6304)
                     /locus_tag="PC592_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF4057202.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYVL
                     VYRENEDKEKNEHDKNLNETINKFKREEEKRIQAKSAARAIAEAKKRVLY"
     gene            complement(6365..7129)
                     /locus_tag="PC592_003272"
     CDS             complement(6365..7129)
                     /locus_tag="PC592_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF4057203.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAEASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMIDTIENFRKSNKTFKEF"
     gene            complement(7411..7677)
                     /locus_tag="PC592_003273"
     CDS             complement(7411..7677)
                     /locus_tag="PC592_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF4057204.1"
                     /translation="MIESRCGILCYECEYKEKVNCKGCTDIKKPFWGEQCPVKSCCEN
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRIVQCKKWAVLAL"
     gene            complement(7719..8528)
                     /locus_tag="PC592_003274"
     CDS             complement(7719..8528)
                     /locus_tag="PC592_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057205.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLVPDASGCMIFKFDKKGIESSFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKANIVDMT
                     IPILENARKQNSIMSVKSISQISCYSERHLNRIFNNSLGMSLKSYLRLLRINLVLQEI
                     QNNKIPFVTLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         3056 a         1109 c         1380 g         3121 t
ORIGIN      
        1 gaaaatttac atataaaact aaaaaatgca agtaattgac tttttaagtt gacaaaatat
       61 tgcatatata ttatgatata aatcataaat taactacaaa tcaatattat atattcgtag
      121 aagaagaaag tagcataaag gaattttaca gagagttaga tttggctgag aactaatatt
      181 ggaatttatg cgaaaaggac tttggagaat actattgtaa ctatgttata atagtggttt
      241 aattcgcctt aagaaaatga gtgagtaaaa ttaattttta ctaataagag tggtaacacg
      301 gatttatatt cgtctcttgg atttttccaa gaggcgtttt ttattataaa cttatttcag
      361 aaaatttaaa actatatatt aaatgaaaag tataaaaata tgatagttaa taaatttata
      421 aattagaaaa ttgtaaaata tactaaagtt agtatcttta cgatttaaat ggagggatga
      481 aaatggaaga agaaaaaatt aactatgctc tggaacagat tccagagaat caaaaacgtg
      541 gttgggtagc tatgttttca gttttagtag caataggtgt ggatttatca tctgttattt
      601 taggagctga gttggcacag agtatgccaa tgaaacaagc aatattgtca gtaattgttg
      661 gttcattttt ttctgcaatt ttgtatacta catgctcttt ggttggttca tctacaagtc
      721 tatctacatc tatgataaca aagtatgtat ttggagaagc tggagcaaaa atattttctc
      781 tagttatagg agtttctcta ttaggatggt ttggagttca agtaggtttc tttgctcaaa
      841 atgcacagat aataataaaa gatatattta atttagatgt gagtatgcag attttaagcc
      901 taataggtgg tctcttgatg atgagtactg caatttatgg atataaggca atggaaaagt
      961 tgagtgtgta ttcagtaccg tttttattag ttcttatgat gttaactata ttcttagctt
     1021 ttagagcaaa tggaattcca gttgatgata atatgaaatc tactatgaca tttgcaggtg
     1081 gagtttctct gtcaatgagt ataataatcg ttggtgcaat tgtatctcct gatataagtc
     1141 gttgggctaa aagtagaaga gactgtgcgc tttcaagctt tttaggaata caatttggaa
     1201 atgcttttat gataatagtt tcgatagtat tagtaaaatg tatgggaact tcagatatta
     1261 tgagaatttt tattacatta gggattgcta taccaggtat aatagtactt acattagctc
     1321 aatggactac aaatacaagt aatgtatatt cagcatcatt aagtatagct cttgtactta
     1381 agaaggctcc tgagaaagta ttaactatag tccttggtat tgtagcaaca ttattggctg
     1441 tatttggaat atatgaaggt tttataggat ttttaaattt acttggaatt gtaattgcac
     1501 ctgttggtgg tgtatataca gcagaatatt atatagtaaa gcaagaactt aaaggctttg
     1561 ataaaggtgt attatataaa ccaatagtta aacgttcaat agtgtcttgg ataatcggta
     1621 tattaataac ttacctttca acatatggat ttataactct tactactata gcacctttag
     1681 atggttttat agcagggttt gtagtacaat ctattattgg aaaagtgctt tgctcaatga
     1741 aaaataatca agaaatagac aaagcagtat aaagaaattt gtttataaag tataaaataa
     1801 attagaaata tgaggagaaa gtaacatgag atttttaaca gaagaaagtg tagataaaat
     1861 agcagttggt gcagccgtgc ttggaactgg aggtggaggt gacccatatg taggtaagtt
     1921 ggttgcaaaa caagccatta aaaagtatgg tcctgtaaaa gtaataagct tagatgaact
     1981 tgatgatgat gctttggtag ttccagtatc tggtatgggt tctcctgtaa ttacaataga
     2041 aaaattactt tcagaagtag agttaactac acctttagaa ataatggaga aattattaaa
     2101 tagaaaagtg gatgttataa ttcctataga aataggagga ataaactctc ttatgccgat
     2161 agcagttgca gctaaaaaag gacttcctat tttagatgca gattctatgg gtagagcttt
     2221 tcctgaagct caaatggtga ctttttatct tgaaggatat gaggcatctc ctgctgtaat
     2281 gtctgatgaa aaaggaaatt ctgctattct ttatcctgta gatggtattt ggtcagaaag
     2341 attagctaga actttaactg tagaaatggg aggaagttct tctattagtg actataattt
     2401 aagtggagct caagttaaaa aagctgctat aggtaatact cttacaatag ctgaaactat
     2461 aggaggattt ttacttgaaa gtaaatctga ttcaaaaggt gctgttgaga atatactaaa
     2521 agaattgagt ggatacaaat tatttgaagg aaaagtaatt gatattaaga gagagttgaa
     2581 aggtggattt actagaggac atgctttttt tgctgggatt aatgaatatg atggagagta
     2641 ttctatatta ttccaaaatg agaacttaat tgccaaaaaa ggtgatacac cactttgtat
     2701 tacaccagat ttaatagcag tgttagattt agaaacagga tttccaataa ctacagagag
     2761 aataaaatat ggctctcgtg ttatggtagt agcttttcct tgtaatgaaa agtggagaac
     2821 agaaaaggga attgagacag ttggacctgg atactttgga tatgatgtgg aatataaaac
     2881 agtagaggaa ttacaaggaa aataaaagtt taggaggaaa ttttgatgta tcgtgtagga
     2941 attgacgttg gaggaacaaa tacagatgct tgtatactgg atggggaatt aaaagtaatt
     3001 cattcagtta aggtggcaac tacaaaggat gttgaaactg gtgtttacaa tgccttaaaa
     3061 aaagttatag atgaaagtaa aattgaccat tcattaataa aatatgctat gcttggtaca
     3121 actcattgta caaatgctat tgtagaaaga aaaagactta ataatgtggc tatgataaga
     3181 ataggaaagc cagcaactac tgccattctt ccttttatag attggccaga ggacttaaga
     3241 gaaaaaatag agttagattc aatattggta tctggtggat atgagtttga tggtagaaag
     3301 ataaatgaac tttgtaaaga tgaagttgta gaattttgca atagaataaa agacaaagtg
     3361 gaaagtgttg caataagtgg agtatttgct ccagtaaata aacaacaaga agaagaagtt
     3421 gcaaaatggg ttagagaaat tctaggggac attcccatat ctttatcaaa tgaaataggt
     3481 aatatcggta tattagaaag agaaaatggg gctattttaa attctgcatt gtctcaagta
     3541 ggtaaagctg tatctttagg atttgaaaaa gcacttaaag atttaggcat agacgctcaa
     3601 atatatttta gtcaaaatga tggaacatta atgaatttag agtatacaat gaaataccca
     3661 atttttacaa ttggatgtgg aataacaaac tctataagag gagcttcctt tttatcaaaa
     3721 gtaaaaaatg caatagtact agatgttgga ggaactacaa gcgacttggg tgtactatac
     3781 aatggattcc ctagagaatc atcaattcca gttacaattg gaggggtaca tacaaacttt
     3841 agaatgccag atgttctaac tattggtctt gctggtggga catgtgtaaa aggcgaaaag
     3901 gataatataa agataggtcc tgaaagtgtg ggatatagaa taactgaaga tgcaataata
     3961 tttggtggaa acactctaac tttatcagat attgttacaa aattagatat ggcatttgaa
     4021 gatagaaaaa gcaatgttga aaacttagat aaagagtatt gtgatgaggt atataagaag
     4081 gttattttaa aattagaaga tgctgtagac caaatgaaga ctagtcaaga tgatgttgaa
     4141 ttggttttaa ctggcggagg aagtataatt gttcctgaaa aactaaaagg cataagcaat
     4201 gttataagac ctcctcatta tactgctgca aatgctattg gtgcagcttt aggacaaata
     4261 agtggagatg tagaaaaagt atatagttta gataaaatgt cgagagaaga tgccatagaa
     4321 gatgcaaaaa aagaggctgt aaataaagct ctaaaagctg gtgctaaaga agatactata
     4381 gaagtattaa acatagaaga tgttccactt gcataccttc ctgggaatgc acttcttata
     4441 aaagtaaaag ttgttggtga tttaatttaa agaataaata taagtaattt cagggtcttt
     4501 aaaataaagt gtgtattctt ctaaaaagtg gtgataatta aaactattaa atatcactaa
     4561 tacaaaggaa ggtgcacact ttttatgttt aacaaaaacg aaatataaaa aaaacttatt
     4621 gaagaatatg atgtaaagac aactacagat attcaagata tgctaaaaga tttatttgca
     4681 agtacaattc atcaaatgtt agaagcagag cttgacaagc atttagatta tgacagatac
     4741 gataataaga acaaaaatac taaaaactct agaaatggat atgaacagcc gatatatacc
     4801 tattttttaa ggtttattgg ctgtttgctt ttgacaggta gaccatacaa tttatacaaa
     4861 ttcttatatt tatactctaa atcattatac attttattgc aaagcatata atcagactta
     4921 gcatttctat atttgctttt acatctggca tataagtgat tccatttgtc aactaactgg
     4981 attttgtact ttttataaaa aactatttta tatagagatt tctgtctttt atcgcattcc
     5041 aactattttt cttactgtat ttgctgtacg aattgtaatc ttatcactta catttgaact
     5101 agcagtcttt gaccaccaat ttgtcttttg ataatcttta cgactaaaag accaaaaaat
     5161 agcattttta tagtgataca ctttttcata ttcttcttta ggatttccaa cctcatcata
     5221 aaacttgtca taagataagt caggaaacat aaaaataaga ttatcatata tttctttgtt
     5281 gttatctccc caccaactag gagcattatt tagtatatcc tctaacacct cttgtgaaat
     5341 aataaaaact ggtatctcca attcaaactg tttttttatc attaatccta ttgaatttga
     5401 gataacctcg ctgtcatcta cattacttaa aaagacaaca ttgccactat taaggtatgt
     5461 agaaactgct gaataaccaa gttctacaaa ccctgctttt aattcagaca taactatttt
     5521 gttcttacca cttatattga tacctcttaa taatgcgata taccttttca tataataatt
     5581 tcacctctaa acatttacat ttttctatgt agcacaaact ggaatttgta tcttttataa
     5641 tttttttaaa gcttttttat atgtaatttc cccaagtata aactgttcta aagcatttat
     5701 ttttttcaga ttcagtattg tatttttcaa caattcttct aataaatcta tttcattcaa
     5761 aatcggttta taaatatgtt tacaacaatt aaattcttca aagtatcttg aaccaaatca
     5821 tatttgatat tctacattga tatggatttg aaaataaggt atctcctgtg ataaaataac
     5881 agtttttatg ttttttaaca tatttttgaa gttctttatt aatcaattta cattctgtac
     5941 atcctttatc aaatacaaat ttacatactt tttttaatat aaaaaatcgg tgcctaattt
     6001 gtaccgattt ttgtttttct tagtaaagaa ctcgcttttt tgcttctgct atagccctag
     6061 cagcactttt tgcttgtatt cttttttctt cttctctttt aaatttattt attgtttcat
     6121 ttagattctt atcatgttca tttttctctt tatcttcgtt ttctctgtat actaacacat
     6181 aatctattat tgattcgttt attatctggg atatactttt attttcatta attcctattc
     6241 tcttaacttc cttaagtaga gtctcatcaa tatgaaccgt tgtttgcttt gtattttttg
     6301 ccactttaat cacctcttaa aaaattctaa cattaaaatt ttttttggtc aataaatttt
     6361 aatattaaaa ttctttaaat gttttatttg attttctaaa attttctatt gtatctatca
     6421 tcttattttt tatattttca cctaatacag aagactttag tctaggattt tcgatatggt
     6481 cataaattgg ttctaaaaat tcgacttcta caggaacaga attaatttta ccaataggtt
     6541 ggtatccttc ataagtatct tttgaatttt ttattactag tggaacaata gggcattttg
     6601 ctttatatgc tatctttaaa gctccacttc taaactctga aaccaatgaa tttggttctt
     6661 taatccatgt taaatctcct tctggaaaca ctgccatact ttgacctgta agtatatttt
     6721 gagaggcttc ggctatactc tttataccct cacgattgtt ttttctgttt acatatacac
     6781 atcttagtaa ttttgcccat tctttaaata taggtatatt tctccaaact ggttcatctg
     6841 caattacaca tccaattggt ctttctacac ttgctgttag tatgaagcta tcaagcatac
     6901 tagaatgatt tacaacaaat agaagtggtt cttttggcaa tgtttcttta ccaataatat
     6961 taagttctat attcactata tctaaagatt ttttagcttg tttttgcata aattcaaatt
     7021 tttcttttaa gctaaattta tcaggattct ttttaatttt aatgagccta ggtatagaag
     7081 atgtaaaacc tataagttga tatgtagcaa attttaagta attattcata agattatctc
     7141 cttaaaataa aattatttat tactgtaaag attttaacat aaaataaaat ttaagtctat
     7201 tttaattcaa ttttctaaca gatatttcaa atacacagag attaagattt tatatttcaa
     7261 attttagtaa tcagatttta tcaataagtt actattctat taatgtaatt aaataacctt
     7321 taaatttaat tacaaaaact gttgcagatt tttctacaac agcttaaaag acttatctta
     7381 taaaaactta ttttataata agaaagtata ttataaggct aggacagccc attttttaca
     7441 ctgaacaatt cttttaccat catcaccttg ttctttgtca tatgcaaatt gattaagcat
     7501 ttcacatgga aatgtatcac atagaccaca atgtgtaagg tttttatttt cacaacaaga
     7561 ttttacagga cattgttcac cccaaaatgg tttcttaata tctgtacaac ctttacaatt
     7621 gactttttcc ttgtactcac attcataaca taaaattcca catcttgatt ctatcattct
     7681 aagtcactcc ttaaatataa attttatatg attgtatatc aaaatttata cttttcattg
     7741 taaaaatcgg acagattttt tatataggtt gttggattaa caccacaaat agatttaaaa
     7801 tcatttataa aatgggattg gtcgtaataa ccaatatctt gtgctaaagt tacaaatggt
     7861 attttattat tttgtatttc ttgcaacaca aggtttatac gaagcagtct aaggtatgat
     7921 ttaagactca taccaagaga attattaaaa attctattta aatgtcgttc actataacaa
     7981 ctaatttggg aaatgctttt aacagacata atagagtttt gttttctggc attttcaaga
     8041 attggtatag tcatatctac tatatttgct ttcaacaagt atgataaaaa taacatatct
     8101 aattgttcta ctaattcttt tatagtactt gttctttcaa aaatagaatt aacctctaag
     8161 ctaaataatg tgttaaaatc ttcaagtgaa atttttaaat ctgtagattc tctttgagaa
     8221 agacctgtca aataatatac tccacctggg cgaaattcaa caaatactct aaaaagtaca
     8281 ttttctatat catttttcac aatagtggtt tttgttgtag ctccccagaa tgaactttct
     8341 ataccttttt tatcaaattt aaatatcata catccactag catcaggtac taatgtaaga
     8401 ttttctttaa tacttgtgtc tggaatagat attgtatagt gtgctatata ctgtcttaac
     8461 aatttatgtg gcaaaatata tgtatactgt ttgcaggtat ttaaaatgtt attgattatt
     8521 ttattcataa gtatatcctc ctgagatata aaaaataagt atactaattt actttttata
     8581 taataaacca gttttgattt aattgaaata ttttaataag atattttgtt aaatttagat
     8641 acaataattg taaggtaaaa tctcaa
//
LOCUS       DAMKOJ010000122         8481 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000122 DAMKOJ010000000
VERSION     DAMKOJ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.131"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            80..1018
                     /locus_tag="PC592_003275"
     CDS             80..1018
                     /locus_tag="PC592_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF4057206.1"
                     /translation="MNKRMKLIPYEINENPRGAKNKFPYGIKQMNVRGMWDEGYTGKN
                     IVVGIIDTGCDVSHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVIQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMGNKLAIMSGTSMSAPYVSGSLALIKEWARDEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNTGKR"
     gene            1532..1960
                     /locus_tag="PC592_003276"
     CDS             1532..1960
                     /locus_tag="PC592_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF4057207.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFIAEGVKSKGKTPEVLDVSLLKPS
                     DLKEENKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMREW
                     EERMQNAGAVIIGGEGITAMEEPDEEAKDECIELGKMLAE"
     gene            complement(2113..2907)
                     /locus_tag="PC592_003277"
     CDS             complement(2113..2907)
                     /locus_tag="PC592_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase"
                     /protein_id="HDF4057208.1"
                     /translation="MEKYANMIKEKLNSGKVLCGVAVSLSDSVVSELIGISGYDFVWI
                     EGEHGALDRKDIQQHMIAAHAGGAASLVRLVNSDPDIVKPIMDMGTDIICFPFINTVQ
                     DAQKAVAACTYPPNGIRGYNPQRASYYGNMNYFDYVKNANNETLKMMLIEQKAGYDNL
                     EEIVKVKGVDIIALGPGDLSLDMGFSGYMDRIEIKDMISNATDICKKYKMPFVTFPSI
                     EKNSIETWVNIGSNMLCFAQDTTFITYVINQLLSFYNEIVPIKKQH"
     gene            3056..3424
                     /locus_tag="PC592_003278"
     CDS             3056..3424
                     /locus_tag="PC592_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4057209.1"
                     /translation="MKYSMTDVSKITEISSSAIRFYEKKGLLLPINRKPSGVRYFYEE
                     DINRLMFIKELKNAGLSIKDIHECFHFCDMGDDTIDKRIQLFQQHKQNIKNKIYELEN
                     CMDRIDEKIYYLKVKKMCKK"
     gene            3739..4101
                     /locus_tag="PC592_003279"
     CDS             3739..4101
                     /locus_tag="PC592_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013281026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDF4057210.1"
                     /translation="MYESRENYLETILILEKKNGIVKSIDIAKQLNYSKASVSRAIGI
                     LKEYGFIIMEVDGDIVLTEEGRKKAEEIYEKHILITKFLVNTLGVSFDIAEKDACRIE
                     HVISKETFEGIKKYLDKN"
     gene            4113..5768
                     /locus_tag="PC592_003280"
     CDS             4113..5768
                     /locus_tag="PC592_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PocR ligand-binding domain-containing protein"
                     /protein_id="HDF4057211.1"
                     /translation="MMDFSESNDEVQKFDWGEVTWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKISIKEKSIIYCPPYSEHEIINTGKVDLVI
                     LITYVPHKFSSLRQLPIVFSENTIQELINVNIIENLANQISNILKLRISVYDSKHKEI
                     FETKKETKFCDICKSIKECNRKLAKGMNNDNFEKMYHCRYGISSLEIPIVLEENIVGY
                     IECGNFIIYKSIDIDNNLSKLSSSSDVDIKYISKVYNELSLIPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKIRKENIRLEEALKKANSKLLEEDYIINPIDMFN
                     NNLKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLIYNDVRDIIKEMIFVLSRTALRD
                     LEDLKLISYLINKYNKKISLVDSDEDLWGVLFEFSNECIDKNRAFWRKDKGNLIENIN
                     KYIQKYYKENISLNSISEVFFISPNYLSSIFNERNKVSITEYINLLRVEESKKYLLDR
                     SFSISDICKKVGFNNSSYFSQIFKKFNNVTPNEYRKNILDNEH"
     gene            5829..6581
                     /locus_tag="PC592_003281"
     CDS             5829..6581
                     /locus_tag="PC592_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF4057212.1"
                     /translation="MFAIIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKVNNDLLKKLVPFTIVGSILGVRCVLSISEDILNVLV
                     VVMILIVAIYTFTSKNLGQEDNFESINNKNLRLGMLMAFIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYIGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(7097..7156)
                     /locus_tag="PC592_003282"
     CDS             complement(7097..7156)
                     /locus_tag="PC592_003282"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057213.1"
                     /translation="MVEYIYYYNNKRIKKIKLE"
     gene            7550..7843
                     /locus_tag="PC592_003283"
     CDS             7550..7843
                     /locus_tag="PC592_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF4057214.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            7824..8465
                     /locus_tag="PC592_003284"
     CDS             7824..8465
                     /locus_tag="PC592_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDF4057215.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVILQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKQNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
BASE COUNT         3352 a          821 c         1377 g         2931 t
ORIGIN      
        1 ttttaatttg atttataaac ctattataaa ataaaattta tgatttttat aagcaataaa
       61 atttttagga ggatatgtga tgaataaaag aatgaaacta attccatatg aaataaatga
      121 gaatccaaga ggtgcaaaaa ataagtttcc ctatggaata aagcaaatga atgttagggg
      181 aatgtgggat gaaggttata ctggtaaaaa tattgtagtt ggtataatag atacaggctg
      241 tgatgtatcc catcctcttt taaaaggaaa aataattggt ggggcaaatt ttagtgatga
      301 cagtaatgga aataaaaata tatatgaaga ttttaatggg catggaactc atgttgcagg
      361 cattatagct gcatctaatt ataataatga agttatggga gtagctccag attgtaaatt
      421 attaatagca aaagcattaa ataaagatgg tactggaaca tatcaaagta taattaatgc
      481 tattaacttt gctgtaaata acaaggttga tattatatct atgtctcttg gaggaaacaa
      541 agatgataag aatttaaaaa atgctgtcat acaagcagta aaaaataata tttctgtagt
      601 gtgtgcagca gggaataatg gagatggaga ctctagtaca agtgaatata gctatccagc
      661 aagttatgct gaggtgatag aagtaggtgc aataaatgag aactatttag ttgaaaagtt
      721 tagtaattca aatactacaa tagatttggt ggctccagga agaaatatta tatcaactta
      781 tatgggtaat aaacttgcta ttatgagtgg tactagtatg agtgcaccat acgtatcagg
      841 ctcattagca ctaattaaag aatgggcaag agatgagttt gaaagagatt tagatgaagc
      901 tgaattgtat gcacaattaa taaaatgtac gagggcactt ggaataccta gaacagaaca
      961 aggaaatgga tacttatatt taaatcttta taaatacaag aatactggta aaagataatt
     1021 tataatttta taataaaata aatagggtat atagttaacg caaatgataa aaattaacta
     1081 agtgtatatt ttgaaataga tatatgaaaa tatttaataa taaggtctat agacctgtta
     1141 tgcaattaga ataataaaaa atatacagta ttatagatag cacatctgaa gaaagatgtg
     1201 ttcttctata tgtctgtata gatgctgtat ataaaaggta aattctagat tgaagttaag
     1261 aaggtataag attatttata atacgaacaa gaatattaag cgtgagaaat attcttataa
     1321 aagatttaga aatataatgt gatattatag gtaaataaag agtatagaaa ataaatgata
     1381 tatattatca ataggtattg aatttcaaaa tcatttgtga taatatatat ttagaaaaat
     1441 aagagatttt agataaagga attttttatt tttagaattt agttagcgat tgctaacttt
     1501 cgattaatta aaaatactac aggaggtaag aatgagtaaa atatatattg tttattggag
     1561 tggaacagga aatactgaaa aaatggcaaa ttttatagct gaaggtgtga agtcaaaagg
     1621 caaaacacca gaggttttag atgtaagttt gttaaagcca agtgatttaa aagaagaaaa
     1681 taaatttgca ttgggttgcc catctatggg agcagagcaa ctagaagaag gatatatgga
     1741 accatttgtg tcagaattag aatctatggt atcaggtaaa caaattggat tatttggttc
     1801 atatggttgg ggaaattgcg aatggatgag agaatgggaa gaacgtatgc aaaatgctgg
     1861 tgcggtaatt ataggtggtg aaggaattac agcaatggaa gaaccagatg aagaagcgaa
     1921 agatgagtgt atagaattag gcaaaatgtt agctgaataa atttgtatac tataaaaata
     1981 gtataagtag taactaatga taatagcagt gtataatact aagagagact aatattatga
     2041 tacataagaa aacaccctta atagagatag ataaaatatt agtctctttt agtataaaat
     2101 tagatttata atttaatgtt gttttttaat tggtacaatc tcattataaa aagacaataa
     2161 ttgattgata acataagtaa taaaggtagt atcttgtgca aaacaaagca tatttgatcc
     2221 aatattaacc catgtttcaa tactgttctt ttctattgaa ggaaaagtaa caaatggcat
     2281 tttatatttt ttgcatatat cagtggcatt agaaatcata tcttttattt caattctatc
     2341 catgtatcca gaaaatccca tgtccaagga taagtcacca ggacctaatg ctataatatc
     2401 aacacccttg acttttacta tttcttcaag gttatcataa cctgccttct gttcaattaa
     2461 catcattttt aatgtttcat tgtttgcgtt tttgacatag tcaaaataat tcatattccc
     2521 ataataagag gctctttgag gattgtatcc tcttataccg tttggaggat aagtacaagc
     2581 tgctactgct ttttgtgcat cttgtactgt attaataaat gggaaacaaa taatatctgt
     2641 tcccatatcc attataggct taacaatgtc agggtcactg tttactaatc gtaccaaaga
     2701 agcagcacca ccagcatgtg cagctatcat atgttgctga atgtctttac gatctaaagc
     2761 accatgttct ccttcaatcc agacaaaatc atatccagat ataccgatta actcacttac
     2821 aactgaatca gacagtgaaa cagctactcc acataagacc tttcctgaat ttagtttttc
     2881 tttaatcata tttgcatatt tttccatata catcatcctt tcttttgtca gtttactttt
     2941 acacttcaaa gaatacaact tcaatctaac ttgaagtcaa tacttttttg ttgactacag
     3001 tataaggtat ttttataata ttcttattcc tataaaattt atggaggtaa agattatgaa
     3061 atattctatg actgatgtat ctaaaataac agaaatttct tcatctgcta ttcgatttta
     3121 tgaaaaaaaa ggtttattac ttcctatcaa tagaaaacca agtggtgttc gctatttcta
     3181 tgaagaagac ataaatcgtc ttatgtttat caaagaatta aaaaatgctg gtttatctat
     3241 taaagatatc catgaatgct ttcatttttg tgatatggga gatgacacaa tagataaaag
     3301 aatccaatta tttcaacaac ataaacaaaa cattaaaaat aaaatatatg aactagaaaa
     3361 ttgcatggat agaatagatg agaaaatata ttacttaaag gtaaaaaaga tgtgtaaaaa
     3421 ataatcctta tagaataagg aaataatttt ttgatttttc taatataagt agtaaattca
     3481 aatggcaaca tttgagaaaa gattttttac aatatatttc tacgaagaat tggacaatgt
     3541 tctatataac tatttatcta tacaatgaaa agaaaattat gatagtatat attaatgtaa
     3601 gtagtaaaaa tatttttgtt tgtaaatatg agtattttta aacactataa atatgaatgt
     3661 tataatatat acttatactt ttctaataat tattattaaa agaatataat agagttgtta
     3721 tatatggagg atgttaaaat gtatgaatca agagaaaatt atttggagac aatacttatt
     3781 ttagaaaaga aaaatggaat tgtaaaatca attgatatag ccaaacagtt aaattatagt
     3841 aaggcaagtg taagtagagc aataggaatt ttaaaagaat atggttttat tataatggaa
     3901 gtagatggtg acattgtttt aaccgaagaa ggaagaaaaa aagcagaaga aatttatgaa
     3961 aaacatattt taatcactaa atttttagta aatacattgg gtgtttcatt tgatatagct
     4021 gaaaaagatg catgtagaat agaacatgtt ataagtaaag agacatttga aggaataaaa
     4081 aaatatttag ataaaaacta agaggtgaat ttatgatgga ttttagtgag tcaaatgatg
     4141 aagtacaaaa atttgattgg ggagaggtta catggataca tgaaccatca aaaacacaat
     4201 ttaatagact tagtgctgga attgtaaggt tctttccagg caactgtcaa gaaaaacatt
     4261 ttcatttaag tgaagaacag cttttatatg tgattcaggg agaaggaata caaatcattg
     4321 atggcaaaaa gattagtata aaggaaaaat ccataattta ttgccctcca tattcggaac
     4381 atgagattat aaatactggt aaagttgatt tagtaatatt aatcacttat gttcctcata
     4441 aattttcaag tttaagacag ttacctatag tattttcaga aaatactatt caagagttaa
     4501 ttaatgtaaa tataattgaa aatcttgcaa atcaaatatc taatatattg aagcttagaa
     4561 tatctgtata tgactcaaaa cataaagaaa tatttgagac taaaaaagag actaaatttt
     4621 gtgatatttg taaaagtata aaagagtgta atagaaaact tgctaaaggt atgaataatg
     4681 acaattttga aaaaatgtat cattgtaggt atgggatttc tagtttggag atacccatag
     4741 tattagaaga aaatatagtt ggatatatag aatgtggaaa tttcataata tacaagtcta
     4801 ttgacataga taataattta tctaaattat caagcagttc agatgttgac ataaaataca
     4861 taagtaaagt ttataacgaa ctttcattaa ttccaaagag tagattatat gtgttaaaag
     4921 agaatttatt aatgatgtct gaatttattc aggaaatagc taagaggaat ttttttgaaa
     4981 atcaacttag tataaaagat gaggaaatat tgaagattag aaaagaaaat ataagacttg
     5041 aagaagcact taaaaaagca aatagtaaat tattagaaga ggattacatt attaatccaa
     5101 tagatatgtt caataataat ttaaaagaat atccctttga attagaactt tatattgaaa
     5161 aagaaattaa aaatatgaat ttagaaggag tttataatct aatagataca aataaattaa
     5221 tatataatga tgttagagat attattaagg aaatgatatt tgttttatcc agaacagcac
     5281 ttagagattt agaagattta aaacttatat cttatttaat aaataaatat aataaaaaaa
     5341 tatcacttgt agacagtgat gaagatttat ggggtgtatt atttgaattt tctaatgagt
     5401 gtattgataa gaatagagca ttttggagaa aagataaggg aaatctgatt gaaaatataa
     5461 acaaatatat acaaaaatat tataaagaaa atataagttt aaatagtata tctgaggtct
     5521 tttttataag tccaaactat ttgagttcta tttttaatga aagaaataag gtctcaataa
     5581 ctgagtatat aaatcttctt agggtagaag aatctaaaaa atatttgtta gatagaagtt
     5641 ttagtattag tgatatttgt aagaaagtag gttttaataa tagtagttac ttttcacaga
     5701 tatttaagaa gtttaataat gtaactccaa atgaatatag aaagaatata ctagataatg
     5761 aacattaaat aaaagtatat aacatatata ttgtaagaaa aattgaaaga gaatgatgga
     5821 ggatttttat gtttgcaatt atttttttat gtataggagg gtttttagca gcttttgtag
     5881 attctatagc aggaggtgga ggacttataa gtatgcctgt tcttatggca attggagtac
     5941 cagtacatct tgctattggt acaaataaat ttgcagcgtc agcaggatgt ataagtagcg
     6001 cttatagata tgcaaagtct ggaaaagtca ataatgacct tttaaaaaaa ttagtaccat
     6061 ttactattgt tggtagtatt ttaggtgtga gatgtgtatt atcaataagt gaagatatat
     6121 taaatgtttt ggttgtagtt atgattttaa tagtagctat ttacaccttt acttctaaaa
     6181 atttaggaca agaagataat tttgaatcta ttaataataa aaatttaaga ttaggtatgc
     6241 tcatggcttt tataatgggt ttttatgatg gtttttttgg tccaggtaca ggaacttttt
     6301 tgacttttgg atttataaaa atatatggat atgatttttt acatgcttct gcaaatacaa
     6361 aaatattaaa cttaacaagt aatataactt cattattatt attcatgata aatggtcaag
     6421 tcgattataa gattgctata gtgtttgcat tagtgatgat aatgggagct tatataggtg
     6481 ctaaagttgc tataaagaaa ggttcaaaga tgataaagcc aatattttta gtaatggcat
     6541 tgtttatggt cgtaaaattg gtatatcaaa cattagttta gtttatagaa cttttaaatt
     6601 tataagtaac tgcaaatctt ttagatttaa cctaatcata tagttttata aaaattctaa
     6661 ttatcttcta atatagttca tatataatac acatataaat tgtaatatta caatagaagg
     6721 attatatatc ataaaaatat aatcttgatt tatgtgtatg aaatatatgg taatttgtag
     6781 gaggaatgtt tatgaacata tcaagaagag ctatgaagat aattgaactg gcacaaaaaa
     6841 ttgctaataa aagaggtgta acagtacaag acgcttggaa tgatgctatg aaagaatata
     6901 aagaaaaata tgaatatgtt gcataaaata tgcgttatat tttaaatata agaaaatata
     6961 aaacaaaaga gcttatctta aaataggatt gtactgagac taaaaagtta gattttatac
     7021 aggaatggaa ttttcattcc tgtattttta attttatgca attttatatt catattcaaa
     7081 tatacgttta acaaggctat tctaatttaa tttttttaat tcttttgtta ttataatagt
     7141 aaatatattc tactatagtt gtatctaact aatagaagtt tttatgtatt tttctacagt
     7201 atgttttttg cttcattctt ctctatttaa atagaattta actacctttt aaattaggtt
     7261 caactaattt taatttgaaa tcaaaaatat acataatata tagaagtata cctgttgtta
     7321 gaattttgat ttaacaattg tgatgcagta cacttttgtt aaattaaaaa attagataaa
     7381 ataagaatta aataaaagcg acttaagtaa attgagaatc ttaatatgaa aattttcaat
     7441 aagtatttag aaataactat ttagaaattt ttctaaatag ttattgaaat aaaatggatg
     7501 ttatgttata ttctatttag atgaaattct aaatagtgag gtgatggtgt tggggtttcc
     7561 agaaacattc aaagctcttt cagaccctat aagaagagaa atattggtta tgttgaggga
     7621 gaataaaatg tcagcaggag aaattagtga aaaatttaat atgacgaatg ctacaatttc
     7681 ttatcatcta tctcaactaa aaaaagcagg actcatattt gaaacaaagt ataagaactt
     7741 tattttctac gaaataaata tttcagtttt cgaagaggtt atgctttggt tttcacaatt
     7801 tatggagaag ggagaaaaag ataatgaaaa aagcgataaa taaacaattt attttatcta
     7861 ctttaatatg ttttatacca tttattgtat caatatattt ttataataga ttaccaaatg
     7921 aagttgcaat tcattttgat aattatggaa atccagataa ttatgctcca aaggttatag
     7981 cagcttttgg tgtaccattg ttaatgctat gtatccattt gtatacatgg tttagacttg
     8041 agaatgagcc taagaaagct aatttttcaa atgttataca aaatttatca aaatggggag
     8101 ttgctatact ttcagtaatt ctacaaataa tgatggtttt atattcaaca ggagttagtt
     8161 tggaatctaa tttttatacg ggattaattt tagggataat agttatttta tttggaaact
     8221 atcttcctaa atgtaaacaa aattactcag taggaataat tttgccatgg actcttaatg
     8281 atgaagataa ttggaataag acacaccatt tagctggatg gatttggctt attggtggaa
     8341 tattattaat tattaatgca tttattaata ttccttttta taatatcttt gtaatctttg
     8401 taattgtaat actaccattt atatattctt atttgatgta taaaatttca ggtaaaaata
     8461 actaatataa aaaataacta a
//
LOCUS       DAMKOJ010000123         8442 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000123 DAMKOJ010000000
VERSION     DAMKOJ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8442
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.132"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            1..117
                     /locus_tag="PC592_003285"
                     /pseudo
     CDS             1..117
                     /locus_tag="PC592_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            118..873
                     /locus_tag="PC592_003286"
     CDS             118..873
                     /locus_tag="PC592_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4057216.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTSPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            1004..2026
                     /locus_tag="PC592_003287"
     CDS             1004..2026
                     /locus_tag="PC592_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4057217.1"
                     /translation="MINKKRLASLILAGALSVSMLTGCSQGGDSGNSKQESNSKSKEV
                     KKIGITQLVEHPALDATKAGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILMTAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNKNISY
                     VKTKQE"
     gene            complement(2188..2745)
                     /locus_tag="PC592_003288"
     CDS             complement(2188..2745)
                     /locus_tag="PC592_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF4057218.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEGEYGK
                     REAILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APSVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGVTIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2772..3827)
                     /locus_tag="PC592_003289"
     CDS             complement(2772..3827)
                     /locus_tag="PC592_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDF4057219.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISQLNRIDKNTIYAIDWGCELTLDREIVDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIIENPFTYTMYVRKTNLSNECVPIQIELEKSKMRFKK
                     GDSIYLDFPQEYLFCFK"
     gene            complement(3828..4511)
                     /gene="modB"
                     /locus_tag="PC592_003290"
     CDS             complement(3828..4511)
                     /gene="modB"
                     /locus_tag="PC592_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDF4057220.1"
                     /translation="MGTDWSPLWISLKTALLSTVITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLSFDKTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKVAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVVISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4660..5472)
                     /gene="modA"
                     /locus_tag="PC592_003291"
     CDS             complement(4660..5472)
                     /gene="modA"
                     /locus_tag="PC592_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4057221.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNESKKDDGKQEKTNKSSDSIE
                     LNVSAAASLKEAMAKIEEEYKKIDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSNVTGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSEEGQKIFEEFGYKKVE"
     gene            5665..6594
                     /locus_tag="PC592_003292"
     CDS             5665..6594
                     /locus_tag="PC592_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057222.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     IKDVEEYINIQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEIKTWDDLTKSNITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGIGGYDLTDTGKTIAKV"
     gene            complement(6756..7205)
                     /locus_tag="PC592_003293"
     CDS             complement(6756..7205)
                     /locus_tag="PC592_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057223.1"
                     /translation="MKNKNNKDKNMFNIKVLRVLGLLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGADCIVFLLFIVECVYLVGRYILKVKINWSDIIESEKDNFINNLLVEKI
                     QEESNIVYNLLNSYVLPYIYKKGKGLMSKTYHMLIYIKEKYYYVNIY"
     gene            complement(7407..8387)
                     /locus_tag="PC592_003294"
     CDS             complement(7407..8387)
                     /locus_tag="PC592_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4057224.1"
                     /translation="MKNSFKNYISLRNKFIIISIVFLLILLILSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLDKLKNYKTAELMIQSSNNYKLESLFITSNIKTRDTII
                     LVHGIGSSYYEMLKVAYGYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHTEINSKNEKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPGILIDYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKELWFIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         2943 a         1378 c         1013 g         3108 t
ORIGIN      
        1 taataactgc catagttata atagctttct tagctactgg taacttgaat atttcactaa
       61 aaaaaaacaa atgcaaagct agtaccaaaa ataaatcaga aaaaagaggt gttgtagatg
      121 ttacaaatta aaaatctttc aaagagtttc cccaatccat acggtgaacc taatactata
      181 tttgaaaatt tatcaattga tatagaagat ggtgaatttg taagtatcat aggtagtaat
      241 ggaactggta aatctacttt attaaatata atctctgggc ttataaagga atcttctggt
      301 caagtattat taaataaaca taacttgtct aatttagctg aacacagaag aactcaaata
      361 gtaagtagag tttttcaaga cccaagtctt ggaacttgtc cttctatgac tgttagggaa
      421 aacttgtctt tagctcttaa taaaggaaaa ctattaaacc taagaaaatg tcttcgttac
      481 aaaagagatt ttttagaaaa tttattggaa ggtgtatctc ttgatttaaa aaaatacctt
      541 gatgttcaag taaaattttt atcaggaggt caaagacaat cattatcact aattatgtcg
      601 tgcttaacaa gtccatcagt tttattactt gatgaacata cagcagcact tgacccaaaa
      661 acatcaaatg aagtaattga attgactaat aagattgtaa gggaaaaaaa tataactaca
      721 cttatggtta ctcacaactt aaaacacgct cttcagtatg gtgatagatt gataatgctt
      781 cataagggtg aagttgtatt agatgtaaaa ggtaaagaaa aagaacaatt aacagttgaa
      841 gaaatcttag aaaaatttga atatgcagtt taaaataata tatctattgt attaaactca
      901 gctttaaaat aaagttaaaa ctataataat tatggttact ttacaataat tcatatgaat
      961 atatgaacat atataataat aaatttttga gggggatata aaaatgatta ataaaaaaag
     1021 attagcaagt ttgattttag ctggtgctct tagtgtatct atgcttacag gttgttcaca
     1081 aggaggagac tctggtaatt caaaacaaga aagtaattct aaaagtaaag aagttaaaaa
     1141 aattggtata actcaactgg ttgaacatcc agcattagat gcaactaagg caggttttgt
     1201 aaaagcatta gaaaagaacg gatttaaaga tggagaaaat attgatatag acttccaaaa
     1261 tgctcaaaat gatatgccta ctacacaaag tattgcaagt aaatttgcat ctgacaagaa
     1321 agatttaata tttgctatat ctactccatc agctcaggca gcatttaatg ctactaaaga
     1381 tatacctata cttatgactg ctgtcagtga ccctgttgct gctggattag ttaaaactct
     1441 tgaaaagcca ggcacaaatg tatctggaac atcagatttt gtttctgtag ataaaggttt
     1501 agaacttctt aagatatttg ctcctaaggc aaaaactata ggagttatgt acaatactag
     1561 tgaagtaaat tccaaagttc aagttgatgc tttaaaagaa tatgcatcta aaaatggctt
     1621 taaagttgtt gaaaaaggta taactacttc aaatgaagtt aatcaaggta tttctagttt
     1681 agttggtaaa atagatgtat tatatgttcc tacagacaac ttagtggctt cttctatgcc
     1741 tatagtttct aaaatagcta ctgagaataa aatacctgtt atagcagctg aatctggtcc
     1801 agttgaaaaa ggtgctcttg cttgtcaagg tatcaactac gaaaaactag gttacaaaac
     1861 aggtgaaatg gcggttaaaa ttttaaatgg cgaatcagta tctgacatgc ctgtggctac
     1921 atcagatgat acagatatca ttgttaatga agatatatta aaagctttag gtatggaaaa
     1981 accttctaat aaaaatattt cttacgtaaa aactaaacaa gaatagaaag atattttcta
     2041 tatacgatta atatgtccgt ttctataaat taatttatag aaacaggcat atatttttgt
     2101 tttaatgtat tatttattta aagattatat aaacgctctt aatttatttt tataaatttt
     2161 acttgtataa actttgtaca atcatattca ttcttctatt ttctttatta ctctacatgg
     2221 atttccaaca gctacagtat ttggtggtat atcttttgta actacacttc ctgcacctat
     2281 tactacatta tcacctatag taactcctgg tgttatgatt acgcccccac ctatccatac
     2341 attatcacct atttttacag gagagccata ttctatacct gaatttctaa gttgtgcatc
     2401 aatcggatga taggctgtat agatttgaac gctcggagct aacattacat tatcacctat
     2461 ttcaatctta caaacatcca agaaaataca gtcataattt gcaaagaaat tttcacctac
     2521 atgtatgtta tatccataat cacacctaat gttttgttct acatttattt gctttccaac
     2581 tgaaccaaat agttgtctta aaatagcttc tctttttcca tattcaccct ctaaagtatt
     2641 attaaatagt ctagttaatt ttttacaata ctctctttct tttactagca attcatcatt
     2701 tgcatagtaa cctttcccag acaacatttt ttctttttcg gtcatataat ttactccttt
     2761 ttattgtaat tttacttaaa gcaaaataaa tattcctgtg gaaaatctaa ataaatgctg
     2821 tcacccttct taaatctcat tttacttttt tctaattcta tttgaatagg tacacattca
     2881 ttagataaat tagtttttct aacatacata gtataagtaa atggattttc tataatatta
     2941 atcaattcaa aacataactt ttcatttaaa tcttcattag aatccaagac cttaatgtga
     3001 tgctctctaa ttcccacata ttctatatta tcaactattt ctctgtctaa tgtcaactcg
     3061 catccccaat ctatagcata aatagtattt ttatctattc tatttaattg ggatatattt
     3121 ttgcaccctg ttatcttagc ttctataagg tactttggag attcaaagag ttctttttta
     3181 ggtctctttg gaagaccttc tcccttgtta tacactataa tgtcatcgca aactcggtag
     3241 gcttcttcaa tatcatgagt aacaaatagt atatctccct tataatcttt taacatattc
     3301 ataagttctt tttccatatt gcttcttaag tgatggtcca gtgctgagaa aggttcatct
     3361 aaaagtaata tatctggaga tgttgccaat gctctagcta gtgctaccct ttgttgttga
     3421 ccaccagata attgccaagg gtatctaccc tcaaacccat ttaatttaag tatatctaaa
     3481 taccttgcta ctatttcctt tttttcactc ttgcttagtt ttaaaagccc aagttctata
     3541 ttttgactta cagtcatatg tggaaacaaa gcatagtttt gaaataagaa acctaccttt
     3601 ctatcttgtg ttgataaatt tatcttcttt tcagaatcaa atagaactct atcatttaat
     3661 acaattttac ctcttgttgg cttctcaaga cctgctatac attttaatgt catacttttt
     3721 ccagaaccag attctcccaa aaaccccagc gtaccttttt cttgtttaat ttctaccttt
     3781 aatttaaaag aggataaatc tttttcaata tctacgtata agctcaacta tccacacctc
     3841 tttcctataa ttttctgctg aaattccgac caataattta gtaataaaat cattgctata
     3901 gatattacta caataatcat aacccacatc atagctttat tcatatctcc accttcaaca
     3961 gcaaaaaata tagctattgg catagtctga gtttttccag gtatatttcc agctatcata
     4021 agcgtagcac caaactcacc aagagctctg gcaaatgaca gcactaatcc accaattatt
     4081 ccaggccatg ctaatggaac tgcaacctta aaaaatactt tccattcatt aagacctaat
     4141 gtcctagcag ctgacaacat attattatca atctgttcaa aagctgacct tgaagttcta
     4201 tacatcatag gaaaagatac cactactgct gaaattacag ttgctgtcca actaaatatt
     4261 aaagtcttgt caaaacttaa taaaaacttc cctataaatc cattcttccc acataacaat
     4321 aataaaaaga atcctacaac tgttggtggc aaaattagtg gaagtgtaaa tagtccatct
     4381 ataagaccct tccacttacc tctatagtta gccataatat atgacacaaa tattcctatt
     4441 acaaaagtta ttactgttga caaaagagct gtcttaagtg atatccataa aggtgaccaa
     4501 tctgttccca tctttccctc cttaatttta aatggaaata gtgaaattaa taactctatt
     4561 aatttcacta tttccatttt attataatac acaattattt tcaattttca tttatttata
     4621 tataatttac actcaattat acataattta tttataagtt tattctactt ttttatatcc
     4681 aaattcttca aaaatctttt gcccttcctc acttagtaaa aattcttcaa atttcttagc
     4741 agcatctaca tttttactag ctttaattac cgaaactgga tatgtaatag gtgaatgagt
     4801 tttttcgtct gttttttcaa ctacttttat cttatcatta ttgacagtat cactgaagta
     4861 aacgaatcca acatcagcat ttcctgattg tacccatgct aaaacttctt ttacatcttt
     4921 tgcaaatact agcttatctt ttaacttatc ttttaaattt aaattagtta acacctcatc
     4981 tgcatactta ccagctggaa cactttcagc ttcaccaaca gcaattttct taactttatc
     5041 tgtagtcaaa tctttcatac cagttacatt actgtcagca gaagaaataa gaactaaatc
     5101 attttttact aaatctttca tagtatcaga aactaataac ttctcttcat ccaaagcttt
     5161 catttgtttt tgacctgctg aaataaataa atcacaaggt gctccttgct ctatttgttg
     5221 ttgtaatgag cctgatgctc catagttaac tgtaagcttt acatttgaat caattttttt
     5281 atattcttct tcaatctttg ccattgcttc ttttaaactt gcagccgccg atacatttaa
     5341 ctctattgaa tcactacttt tatttgtttt ttcttgtttt ccatcatcct ttttgctttc
     5401 attactattg catccaactg tccccaaagt taaacatgca actagtccta atattcccaa
     5461 tatttttttc ataccaatct ccctttttgt aaatttaata catattttaa catgttttat
     5521 tatgttttat catgttttgt catgtatagt ttaattatat atacctgata ataaattttc
     5581 aagtaattta tttacattac ttttaaatat tttgctacat tttccttttt ttaatgttaa
     5641 aataacctta tatggaggtg gattatggac tcattatcat ctttgacacc tgtcgaggta
     5701 gctgaattat taaaaataac aaaaaatact gtctatgaat taatcaaaag aggtgaactt
     5761 ccttcttata aagtagggaa aaaaataaga gttgatatta aagatgttga agaatatatc
     5821 aacatacaaa aaactggtaa agtaaaagat acacatttta acaataaaaa tatagatata
     5881 aataataatt ttaaaattat tatctctggt caagatgtaa tattagacat tttagctagg
     5941 tctgttgaaa aaaaattgga tggaataagt acatttcgct cttatatagg tagttataat
     6001 gctttgtatg agttatataa tggcagagtt tccatagcat catcccatct atgggatttc
     6061 gaaacggatg aatataatag cacttttgtt aaaaaactat tgccagggat accatgtgta
     6121 cttataaatc tagcttatcg aatgcaaggt ttctatgttg ctaaaggaaa tcctaaagaa
     6181 ataaaaacct gggatgattt aacaaaatca aacataacca ttgtaaatag agaaaaaggt
     6241 tctggaacta gggttctact agatggtaag cttaggcttc taaactttaa tggtaaacat
     6301 ataaaaggtt atgataatga agagttatca catcttggag ttgcaagtac tgtttctcgt
     6361 ggaatagctg atgttggttt gggaaatgaa aaagctgctt tacaagtaaa taatatcgac
     6421 tttattcctc ttcacaagga gcgttatgat ttagttatta aaaaagagga cttacaaaat
     6481 ccagtttacc aaactataat taacataata aactctcctg agtttaaagc tgaacttcaa
     6541 ggcattggtg gatatgattt aaccgatact ggaaaaacta tagcaaaagt ttaaaattaa
     6601 aatcgcaatc tattttataa gatttataat ttttcacaaa atttataact taaacacgaa
     6661 ataaattgcg atttttagta tctcaaaaaa tttatatctt tcattttatc atctaatata
     6721 aaatttaata taattaattg tgtaagtata ttatattaat atatatttac ataatagtat
     6781 ttttccttaa tatagattaa catatgatat gttttagaca tcaatccctt tcctttctta
     6841 tatatatatg gtaacacata tgagtttaat agattatata caatattgct ttcttcttgt
     6901 attttttcaa ctaacaagtt atttataaaa ttatcttttt cgctctcaat aatatcactc
     6961 caatttatct taacttttaa tatatatctt cccactaggt atacacactc tacaataaat
     7021 aataaaaata caatacagtc agcacctgtt gtcttatata aatttcccga tactaatggc
     7081 ttagcgaaga aattataaaa attcaaagta tctcctgtat aatcaaaaag tattagtagt
     7141 agtcctagga ctctcaatac cttaatatta aacatatttt tatctttatt atttttattt
     7201 ttcatatata ctacctctct tttctttaga ttttattgta atctaatact aactctttta
     7261 tttgaggtat aaatgaattt aattggtaat tattttcatt tttactagaa attaattcac
     7321 attaataaag aaaacttata tttaaacata aaaatagcct atctattttt aataaataca
     7381 aaaataaata agctactaat attcaactaa cttttatcac ttaaaacatt actatctata
     7441 aatttaaata ttttattgaa gtatactgta ctatcatgct caaatccatc aacatgacca
     7501 ataccttcta taaaccatag ttctttttta tcatgtttaa ctaaatcata cattttttta
     7561 ctattttgat aattacaaac agtatctttt gtcccatgta taaacagtat aggtacatta
     7621 gatttctcga ctgactcata tggctttaca tcactgtacc aaaatccaga tttaaactta
     7681 ttatataaat ctccacaagt tactacataa tcgattaata tacctggtat tcgtttttct
     7741 agtactccca ttctaattgc atctttcatt tcagaatacg gagaatccaa tatataaaaa
     7801 tcgaccttct cattttttga atttatctct gtatgcatag cagctgttcc tgcccccatg
     7861 gaaaatccat gcactcctaa tcttccttca ggaaatttat tttttacaaa tttaactaga
     7921 ctatctaaat catacctttc ataaagacca aatgtgtaat tatctccgcc actattacct
     7981 gtatttcttt gattataaac taatacatta taacctttat ctaaatatcc atatgctacc
     8041 tttaacattt catagtaact acttccaatt ccatgaacaa gtataatagt atctcttgtc
     8101 tttatatttg aagttatgaa aagactttca agcttgtaat tattagaact ttgtatcatt
     8161 aattcagctg tcttgtagtt ttttaattta tccagtggtt tatcttttct ctcagaaaat
     8221 atttttacta tatcttcgtt ttttattaat tgctctaagc caactgaact attgtacact
     8281 aatttgccaa atatataaga tagaattaat aggattaata gaaacacaat tgatataatt
     8341 ataaatttat ttcttaaact aatataattt ttaaaactat ttttcatatt tatttaccat
     8401 gcaattttcc tatattatat tttttaagta atagcataat tg
//
LOCUS       DAMKOJ010000124         8433 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.133, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000124 DAMKOJ010000000
VERSION     DAMKOJ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.133"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            33..2156
                     /locus_tag="PC592_003295"
     CDS             33..2156
                     /locus_tag="PC592_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF4057225.1"
                     /translation="MDSYRQLKAKIPCKETGIEIRRTLCDICSPGVHCGIDAYVKNGK
                     VIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKRIGKRGEGKFKTISWDEAY
                     REIAEKLNKVKSEYGAKHVAFFTGYGKWYRPFLQRFASSFGSPNYGTESSSCSTSAQM
                     AGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLTKLKEKGLKFIIVDPRITP
                     TTQKLADLHLRIKPGTDGALALGMANLFIQRDLIDKEYIEKHIHGFNEYKEYVKLFDL
                     DTVSRITRVSKDNIVKAVEMLSQGSFCINESAAPIVHHQNGFQNYRAMMSLSAITGNY
                     DRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERIGGERFPLWNEMVTQFQAM
                     DLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALDSVDFFVNIDLFMTDTSKYAD
                     ILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVEILSDLANVMNIDDDLLKA
                     GYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSYTREGYDTSTSRFELKSTI
                     IEKYKDFGLDALPTYRGFNDNIDDEYTYLLTSGARISNALHSRLHDIKLSRILKNEAS
                     CDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLYKNIHMYHGYREADINSII
                     CDNFDPYSGFPAYRSCKCKIEKTNR"
     gene            2170..2592
                     /locus_tag="PC592_003296"
     CDS             2170..2592
                     /locus_tag="PC592_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4057226.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GESIEYFSLACIHCDEPKCLDVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGMDGKANKCNGCVERYKCGMDSPCVMVCPTGALKFNK"
     gene            3000..3803
                     /locus_tag="PC592_003297"
     CDS             3000..3803
                     /locus_tag="PC592_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF4057227.1"
                     /translation="MKKIKLIIMLALVSAFLITGCSSENNKNKEEQKTIRVATSGTYY
                     PFAFKEKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYDFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKLVEPPIQFGAC
                     SFALQKNEKGERWTKEINKVIEDMHKDGTLTKISKAWLGKDITKEPINE"
     gene            3796..4464
                     /locus_tag="PC592_003298"
     CDS             3796..4464
                     /locus_tag="PC592_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF4057228.1"
                     /translation="MSSFNFEFCLNIFPFLIKALGITILISIIAFFISILLGVILAFF
                     TQTKSKILQYITRVYVSFFRGTPLLIQIFFFYFGFPMVFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMVTILIYWAVSIMLSNIQSKVEKRI
                     GKAY"
     gene            4699..5361
                     /locus_tag="PC592_003299"
     CDS             4699..5361
                     /locus_tag="PC592_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF4057229.1"
                     /translation="MIFNMKYFLELFPIIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDKGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            5421..6218
                     /locus_tag="PC592_003300"
     CDS             5421..6218
                     /locus_tag="PC592_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF4057230.1"
                     /translation="MIKRNIIKCLVAVLSLTVLVTGCSKKEEVKDEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVAASVNKD
                     NLFEEKVYGDGTNGLQDLDLGRVSAWIDAELTVIGDAKKANMKVRVLDEKLSVTNIAY
                     FFKKNDEKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            6351..7526
                     /locus_tag="PC592_003301"
     CDS             6351..7526
                     /locus_tag="PC592_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4057231.1"
                     /translation="MIETKIKSIALKNREKIIKIRRQIHSNPELAFKEFKTSKLIKEE
                     LNKLNIEYIDVAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSINDNMHA
                     CGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGVDALAT
                     GHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAVYSSIQ
                     QIVSRKINPVIPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISQEKVIEISKILENIV
                     RGVCKSNGADCKFEKSMGGDAVINDKDMIELGKKSACKILGYENVEMIDFPAMTGEDF
                     AIYMKERPGLFMYIGVGSEEKNINYRLHNNKFDIDEKCLSVASSLFSQLAVDYLCQL"
     gene            7635..8384
                     /locus_tag="PC592_003302"
     CDS             7635..8384
                     /locus_tag="PC592_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF4057232.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEINQSEVVAILGPSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVERTTKKDIANLRKHTSMVFQNYNLFKNKTALENIM
                     EALIVVHKKGKQEAREISLKLLDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDKGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIKKEEVFS"
BASE COUNT         3345 a          867 c         1569 g         2652 t
ORIGIN      
        1 tatatttatt attaggaaag gaaaatatta atatggatag ttatagacaa cttaaagcta
       61 aaataccatg taaggaaaca ggtatagaaa taaggagaac tttatgtgat atttgttccc
      121 caggagtaca ttgtggaatt gatgcatacg ttaaaaatgg taaagtaata aaaatagaag
      181 gtacaaaaga acatccaatg aataaaggat tgttatgtac aaaaggtctt tgcaatagag
      241 aatatatcta tagagaagat agaataaaaa cacctctaaa aagaattgga aaaagaggtg
      301 aaggaaaatt taagacaata tcatgggatg aagcttatag agaaatagca gaaaaattaa
      361 ataaagtaaa atctgagtat ggagcaaagc atgtagcttt ttttacaggt tatggaaagt
      421 ggtatagacc gtttttacaa aggtttgcat cttcatttgg ttctcctaat tatggtacag
      481 aatctagttc atgttcaaca tcagcacaga tggcgggaaa tgttgctact ggaagaaact
      541 ttacaatgca agatatggag aatgcaaaaa cttacttagg atggggattt aatccatact
      601 actctaaatt tttaaatagt gtaaatctaa caaaattaaa agaaaaaggt ctaaaattta
      661 taattgtaga ccctaggata acaccaacaa cccaaaaact agcggattta catttaagaa
      721 ttaaacctgg aactgatggg gctttagctc ttggaatggc gaatctattt atacaaagag
      781 atttaataga taaagaatac atagaaaagc atatacatgg atttaatgaa tataaagaat
      841 atgtaaaact atttgattta gatactgtaa gtagaattac aagagtttct aaagacaata
      901 tagtaaaagc tgtagaaatg ttgtcacaag gttcattttg tataaatgaa agtgcagctc
      961 caatagttca tcatcaaaat ggattccaaa actatagagc aatgatgtct ttatctgcta
     1021 taacaggcaa ttatgataga ataggtggaa acataccaaa acaagattac tttgctggta
     1081 agataggtgg attccaaaca ctagaaaaag agtttgtaaa agaagttcta cctaaaaata
     1141 taaatgaaag aattggtgga gaaagattcc ctctatggaa tgaaatggta actcaatttc
     1201 aagctatgga tttacctagg caaatagaag aaaagacacc atatgaaata agagctttgt
     1261 tttgtcatgg gataaatgct agaatgtttc ctaattcagg gagacttttt aaagcattgg
     1321 atagtgtaga tttttttgtg aatatagatt tatttatgac agatacatca aaatatgcag
     1381 atatactttt acctgcatgt acatcattcg agagagaaga atgtaagagc tatccaggag
     1441 ggtatattac atataccaaa aaagttattg ataaattata cgattcaaaa tcagatgtag
     1501 aaatactttc agatttagca aatgttatga atatagatga tgatttatta aaagcaggtt
     1561 atgaagcaag tataagacat atgtttaaaa atacgtgtgt agatgtagat aaacttaaag
     1621 aaagtgattt accattaaaa tgtaaagatt ttaagccata tatagtaggt tcatatacaa
     1681 gagaagggta tgatactagt acttctaggt ttgaattaaa atctacaatt attgaaaaat
     1741 ataaagattt tgggctggat gcactaccaa catatagagg atttaatgat aatatagatg
     1801 atgaatatac ttatttattg acatcaggag caagaatttc aaatgcacta cattcaagac
     1861 ttcatgacat caaactttca agaatattaa aaaatgaagc tagttgtgat atttctagct
     1921 tagatgcaaa agaattgggt gttatcagtg gagattatat aaaaataact actaagatag
     1981 gaagtttgga tgtaaaagtc aatgttactg atagagtctt atataagaat atacatatgt
     2041 atcatggata tagagaagct gatataaata gtattatttg tgataatttt gacccttata
     2101 gtggattccc tgcgtataga agttgcaagt gtaagattga aaaaacaaat agataaatgg
     2161 agagatataa tgaaaagttt atttaaattt aataaagaat tatgtacagc atgtggagca
     2221 tgtttgcttg catgtataga ccaaaatgat aataatatag ataatggtga actttttaga
     2281 catgtattta caatagagga aggtgaaagt atagaatatt tttcattagc atgtatacat
     2341 tgtgatgagc caaaatgttt agatgtatgt cctaaaaatt gttttaaaaa agaagaagga
     2401 ttcgttgtat tagataatca aaactgtata gggtgtaaac tttgtgaaaa agcttgtgaa
     2461 tatggagccc taatttatgg aatggatggt aaggcaaata agtgtaatgg ttgtgtcgag
     2521 agatataagt gtggtatgga ttcaccttgt gtaatggtat gtcctacagg agcattgaaa
     2581 tttaataaat agattaaata tatagagtga cttatactta gatataagat atttttacaa
     2641 aaagctatat tgagtttgtt ataataaaaa ctcaatatag ctttttgtat ggatatagtt
     2701 ggatactata atatgattct tagtaatagt tttttgctat tggacaaaga ctgtaaaaca
     2761 tattaaactt atgttgttca aagtcgaagt ataatataat aactagaaaa ttgatttata
     2821 gtgttataaa agcaaattta ggaaggtata aaatctgaag taattcttta ctacagtatc
     2881 aatacttgga gttctgttat ggcagagtca ttaaacaatt ataatggtac aagtgattca
     2941 attgctggaa atgtattata taaaaattta aaaaaagatt aaaaaggaga gaataaatta
     3001 tgaaaaaaat taaattaatt attatgcttg ccttggtatc agcattttta attacaggat
     3061 gctcatcaga aaataataaa aataaagaag aacaaaaaac tataagagtt gcaacatcag
     3121 gaacatatta cccttttgct tttaaagaga aagataaact taaaggattt gaagtagatt
     3181 tttgggatga atttgctaaa cgaactaatt gtaaagttga atgggtatta actgatttta
     3241 gtggattatt tggattatta gaagctgata aagcagatgt tgtatctgct caacttactg
     3301 caacacctga aagagagaag aaatatgatt tttcagatgc ttataactat agtggaacaa
     3361 atattattgt tagagaagat gatactagta taaaatcaat agatgattta gttggaaaga
     3421 aagtaggtgt gggtactgga gcagtagcaa atgaaatact aaaagaaaag tacccaaatg
     3481 atgaaataaa aatagtaaat tattcaagtg caactcttaa aggaaattat caagacctag
     3541 aaatgggaag attagatgca gtagttgcgc aggatgttga ggctttaata gctataaaag
     3601 aacaaaaatt aaatcttaaa ttggtagaac ctccaattca gttcggagcc tgttcctttg
     3661 cgcttcaaaa aaatgaaaag ggtgaaagat ggacaaaaga aataaacaaa gtaattgaag
     3721 atatgcataa agatgggact ttgactaaaa tatctaaagc ctggctagga aaagatatta
     3781 ctaaggagcc tattaatgag tagttttaat tttgaatttt gtctaaatat atttccattt
     3841 ttgattaaag cattgggaat aacaatacta atatctatta ttgcattttt tatatcaata
     3901 ttattaggtg taatacttgc atttttcaca cagacaaaat caaaaatttt gcaatacata
     3961 actagagtgt acgtttcatt ttttagagga acaccacttt taattcaaat atttttcttt
     4021 tactttggat ttccaatggt attttctttt atgaaagatt gttcccctta tttagcaata
     4081 gtaatttgtt taggtgtaaa ttcatctgca tatatggctg aaattatacg agcatctatt
     4141 gagagtgttg ataaaggaca acaggaagca tgttatgctt ttgggttaag taaatatcaa
     4201 tcaatggtta aaataattct acctcaagca gctacatctg cagtacctcc tattgtaagt
     4261 tgtacactag atataattaa aggttcttct ttaggtctaa ctataggaat acaagattta
     4321 atgggagtag ctcaagtaga ggctgcttca agttttaaat attttgagat atatatggta
     4381 acgatactaa tttactgggc agtatctata atgttgagta atatacaaag caaagttgaa
     4441 aaaagaatag gaaaagcata ttagatttca atatttaaaa atgggatgat atagatatat
     4501 tatcacttgt aaataaattt ttaattttag aaaaacaaat ttagtaattc taaatattga
     4561 gaaaatataa tacaaaatga actttataat caagttgaaa aatggttttt tctattgaaa
     4621 aataaataaa attctattgt aatttaatat gtgacaaaag tttgtaaaaa acaacattaa
     4681 gctgggggga cttattttat gatttttaat atgaaatatt ttttagaatt atttccaata
     4741 ataatgaaat cgttcaatgt aactgtgatt ttggcaataa gttcattagt attttcatta
     4801 attataggta caatagtagc attatcatct tattacaaag ttaaagtatt gaatcaaata
     4861 tgtaaagtat atgtatctat ctttagaggt acacctctta tgccacagtt attcttttta
     4921 tattttggat tagcatatat gagcgatttt gttaaaaata tggacccagt atttgcaaca
     4981 tctatagtgc ttagtttaaa tatgggagct tatatgtctg aaacgataag ggcttctata
     5041 ctttcaattg ataaaggtca gatagaagca gcatatgcaa tgggattaac aaatttacaa
     5101 acaatgaaaa ggatagtgat accacaggct gtaagagttg cactgccatc attattcaat
     5161 aattttatag atttaattaa agggtcttct gtagcttttg ttgttggagt aaatgacata
     5221 atgggtgctg ctaaatcaca aggagcgttg agttttaagt tctttgaagt gtatggagca
     5281 gttatggtaa tttactggtg tataataact cctttagggt gggggcaaaa aaaattagaa
     5341 aagaaaataa gcaattatta agttattaag aaaatacata aaagtatttt taaataaaaa
     5401 atggtgtgag gagaagagat atgataaaaa gaaatattat aaaatgttta gtggcagttt
     5461 tatcgttaac agttttagtt actggttgtt caaaaaaaga ggaagtaaag gatgaaaaag
     5521 ttataactgt agcttcatct aattcagctg acccatattc ttatgttgat aatggtgagc
     5581 ataagggttt tgaagttgac atgtggaaag agattggtaa aagaagtgga tataagataa
     5641 aaatggaacc aacaggtttt agttctatat ttgggatgtt agattctggt aaagttgatg
     5701 tggcagccaa cttctttgga atgtctaaag aaagattaga aaaatacgat gcttctatac
     5761 cttatggttc tgattctgta tgtatagctg taaaagatgg aaacaacgaa attaataaac
     5821 ttgaagattt aaaaggaaaa gttgtagcag tttcagaagg ttctcaaggg caacaggttg
     5881 cagctagtgt taataaagat aatttatttg aagaaaaggt ttacggtgat ggaactaatg
     5941 gtcttcaaga tttagattta ggaagagtta gtgcatggat tgacgcagag cttactgtta
     6001 taggagacgc taaaaaagct aatatgaagg taagagtatt agatgaaaaa ttatcagtta
     6061 ctaatatagc atacttcttt aagaaaaatg atgaaaaatc taaaactata aaagaagatg
     6121 taaacaaagc aatagaagaa atgcttgcag atggaacagt gaaaaaaata tctgaaaaat
     6181 ggtttggaat ggatgtaagt gctgatatac aaaaataaat actttaaaat taaaatataa
     6241 aactgtgata actatagata agtatactaa atttatctat agttatctgt gtattacaat
     6301 gtatttagat tagtctttat aaattaaaat gagttatgga ggtcttgcaa atgattgaaa
     6361 ctaaaataaa atccattgca ctaaaaaata gagaaaaaat tataaaaata agacgacaga
     6421 tacacagtaa tccagagtta gcatttaaag aatttaaaac atccaaactt ataaaagaag
     6481 agctaaataa acttaatata gaatacatag atgttgctgg cacaggagta ttagctacta
     6541 taaaaggaaa aaataatggt gggaaaacta tattactaag agcggatatg gatgcccttc
     6601 caatcaaaga ggaaaatgat ttagaattta aatcaataaa tgataatatg catgcttgtg
     6661 ggcatgatgc acatgtttca tggttgttag gaacagcaat gattttaaat gacataaaag
     6721 aagaattgaa tggaaatgta aaattactat ttcaacctgg cgaagaaaaa ggtggttctg
     6781 atattgtaat taaagaaaat gtacttgaag gtgtggatgc attagcgact ggtcattgtt
     6841 ggccaactat tgaatcagga aaaattggaa tcgctagaaa ttgtgctatg gcagcgacta
     6901 atacttttga aataacaata attggcaagg gtgggcatgg agcagagcct cataattgta
     6961 tagacccaat tgcagttgga aatgcagtat attcatccat tcaacagata gtttcaagaa
     7021 aaattaaccc agttatacct gtagtagtgt ctgtttgctc ttttaattct ggtgtttcta
     7081 aaaatataat accagatgta tgcacacttc aaggaaccat tagagcgata agtcaagaaa
     7141 aagtaattga aataagtaaa attctagaaa atatagtaag aggtgtctgt aaatcaaatg
     7201 gagcagattg taagtttgaa aagagcatgg gaggggatgc tgttataaat gataaagata
     7261 tgattgagtt gggaaaaaag agcgcttgta aaatacttgg atatgaaaat gttgaaatga
     7321 ttgattttcc tgcaatgacg ggtgaggact ttgctattta tatgaaagaa agacctggtt
     7381 tgtttatgta tataggcgta ggaagtgaag aaaaaaatat aaattacaga ttgcataata
     7441 acaagtttga tatagatgaa aaatgtctta gcgtagcatc ttctttattc tcacaacttg
     7501 cagtagatta tttatgtcaa ctatagagta cattcataaa aatatattta gcctattttt
     7561 aaatttaatg ctagtatatt aattttaatg tagaaaatat tatttattat atttatttaa
     7621 aaaggtggat aacaatgata aaagtagaaa atttacataa aagttttaaa gggacagaag
     7681 ttcttaaagg cataaatcta gaaataaatc aaagtgaagt agtagctata cttggcccat
     7741 ctggaacagg taaatctaca ttgcttagat gtttaaatta tctagttgaa cctacaaaag
     7801 gaaaaataat gattggggat gtaaaggtag atgtagaaag gacaacgaaa aaagatatag
     7861 ctaatttaag aaaacataca tctatggtgt ttcaaaatta taacttattt aaaaataaaa
     7921 cagctttaga aaatataatg gaagcattaa tagtagtaca taaaaagggt aagcaagaag
     7981 ctagagaaat atctttaaaa ctattagata aagtaggtat gttggatagg aaagattttt
     8041 atccatcaaa attgtctggt gggcagcaac aaaggatagg tatagcaaga gcgatggcag
     8101 taaatccaaa tgtaatatta tttgatgagc caacatctgc acttgaccca gaacttgttg
     8161 gagaagtttt aagcgttata aaatcgcttg caaaagaagg tataacgatg cttattgtaa
     8221 ctcatgaaat aaattttgca aaagaagttg ctgataaaat tatatttatg gataagggcg
     8281 taatagctga agaaggaact cctgatgaaa tatttaataa tcctaaaaat gaaagaactg
     8341 caaagttttt aaatatcatt aaaaaagaag aagtatttag ttaaaagtat ataaattaag
     8401 tattagaaga tatgtaagat atcctcatta aat
//
LOCUS       DAMKOJ010000125         8421 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.134, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000125 DAMKOJ010000000
VERSION     DAMKOJ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8421
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.134"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(79..687)
                     /locus_tag="PC592_003303"
     CDS             complement(79..687)
                     /locus_tag="PC592_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDF4057233.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISN
                     FYYDDKGKKVFSKDKLDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(796..3534)
                     /locus_tag="PC592_003304"
     CDS             complement(796..3534)
                     /locus_tag="PC592_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HDF4057234.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNISLYTVSINMYRIILLW
                     IFGYSIVYISNFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFRDINWNMIIVLINVCISLFNLLY
                     LLNKLDSNIEHYKLIKDLTYFIFFTTIIGFVAIYKINIVDSNRFIGVIYLLLCNHTYY
                     VYVYSLRNRVVYPYYELDSINKKLSKKSEQLGKINLVIEKDMIIQRKLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMDNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNGKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRHINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCTSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLVE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNSIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIEKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKIIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3682..4473)
                     /locus_tag="PC592_003305"
     CDS             complement(3682..4473)
                     /locus_tag="PC592_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF4057235.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKALDEIKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIQIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4510..5166)
                     /locus_tag="PC592_003306"
     CDS             complement(4510..5166)
                     /locus_tag="PC592_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057236.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSAINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALVILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5159..6124)
                     /locus_tag="PC592_003307"
     CDS             complement(5159..6124)
                     /locus_tag="PC592_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDF4057237.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGNVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERRTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6230..6336)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6502..7080)
                     /locus_tag="PC592_003308"
     CDS             complement(6502..7080)
                     /locus_tag="PC592_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF4057238.1"
                     /translation="MRRKFVFWTPDMHCSTPLLKELFNIVMNESTIKIEYSSKQKNSI
                     RTIVPIGLYAMNGLWYCPAYCIKSESIKEFRADRIVKILSIENLSNKKYNVLSSIHDY
                     FKNMEVGTDYRIKINLADEGVKHCETEFLLARGLKILSKGGYIDMYIPKSTLNWVAEY
                     FLTFGKNATIIEPIELKHLILFNIFLIMMFYS"
     gene            7236..7523
                     /locus_tag="PC592_003309"
     CDS             7236..7523
                     /locus_tag="PC592_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057239.1"
                     /translation="MNSCWERAVYCNPNGVLKRGVYVLTIKEKDSNNDKDSLVNRSNV
                     YRVNIRLKKETFTEMFGYIPKRPGVGQIVDMDFDFTKLDIVMPHPIYSWMG"
     gene            complement(7802..8401)
                     /locus_tag="PC592_003310"
     CDS             complement(7802..8401)
                     /locus_tag="PC592_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057240.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTRNNEKPNENAGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLITEGERLVKDIDKRIEKLDKVSDEDMKKSQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2714 a         1414 c          804 g         3489 t
ORIGIN      
        1 ctaaaaattc tataaaaaaa taagatacat atccataaaa taccttccta tagatacata
       61 tcttacctat ataaaaactt attctatata aaaacgccat aaaaaatctt ttgcttcttc
      121 tgcataatct atatttatac gtttactagt ttttatatct aatttatctt tactaaatac
      181 tttctttcct ttatcatcat aataaaaatt acttatatat aattcttcac ccattatact
      241 cttactattt agacttctat ctatttttaa tgctttgcaa agttttcctg gtccattagt
      301 aatatttttt acttgatatt tactcaactc agtgtaagct ttgttgtatc tattcataga
      361 tatctcatcc aaagaagtta taggctctac ccctcttatt aatacacact ctggaacatt
      421 ttctatattt gcagataaat ttaagcaatt atacatacca tagattaaat aaacatatat
      481 atgtccacca tctaaatata acggcttcgt tctatctgtt tttttattgc catatacatg
      541 tgctccttta tcatttacac ccatatatgc ttccgtctct atgattttgg taacaattac
      601 tttattttca tatttcctta ttaggtattt acctaatatt gattttgcta aatcaattcc
      661 atttttccta aaaaaatcct tttccaaaat ttcacctcat aaaatttatt tgcaacgcat
      721 caaatacaac taaagtaata aataaaatta actcttatta atgtgatata tataaacaat
      781 aaattccgac atttattatt tatatatatc aaaaaattct atctcaaact tttcaatatt
      841 atcattgtaa tttgaattat catatacttc ttcaacaacc tctttaattg ggaatataat
      901 ttttacatta gttccttctc ctaccttgct atctatataa atctttccat tttgaatttc
      961 aatcaacgat tttgtgaggc ataaccctat accacttcca aattcatttg atatgccact
     1021 gttttcaatt tgtttaaatc gattaaatat atcatttaat ttttctttct ctatacccac
     1081 tccagtatct tttataatta tctctactgt ttcgtctttt ttatatatac ctacaaggat
     1141 ttctcctcct tctaaagtaa attttataga atttgataat atatttagta ttattctttc
     1201 tatagattct gggtcaagcc ctaccataac agtttcttca tctgtatcaa aaattaaatc
     1261 tattccttta gacttagcat aactactaat agatgtaact attctttctg ttatgtcaat
     1321 aatatcaaaa ttaaccgctt taatcttata tatgtctgac ttaacttgag aaatatttat
     1381 tatattatct attaatctca ataatctaaa catattttgt tttgttattt ttatgtgttc
     1441 ttttaatata tcctgaaaat caattatttt tcctttttta taaagatttt caacaagttg
     1501 aactgaactg tatatattat ttaaaggtgt cttaagttca tgagatatat tagcataaaa
     1561 ctccatcttc atttggtcat actgtctttg ttttattaat gctttcttaa gtctttcaga
     1621 ctctctttgc acacttaaat ctttaataat tctcactcta cttctttttt gtccaaagta
     1681 taatgttctt gatatcattt ttacttcttt gatgtgatta ttttcattta ctatatggat
     1741 actcttctct ctttctccta tatttaaatt gtttatgtat ttttttacta atatatttct
     1801 atatttttgt gttgtaactc ctagtacatc actagaaatt ccaaacaact ctctgaaagc
     1861 tctatttgta tataatactc ttgatgtact taaatcttca agaaaaatag cctctggtat
     1921 aacatccagt aatttttcgt atattatttt ttgttcattt actgttctaa gaatatttat
     1981 ctctttagtt atatctctaa atgtaagcaa tttaaagagt ttattatctg accaatagtc
     2041 tccaactcta acttcttcaa catgctcttc accttctgaa tcagacatca caaaattaac
     2101 tatacagttt gctgtgtcat tgtaacttac tatttcagct ttcttttctt gtgttaaatt
     2161 taatctttta aattccctat tgtcaaagaa atctatgtta aaagtttcaa aatattgttc
     2221 taatgtcata tcgactaaat cacttgaagt acatttaaaa ctcttttcat attttttatt
     2281 tatacttatt accttattct tctttatacc gccttcagca cttcttacaa gtataggaga
     2341 tggaatattt agtataatgt tttcatagtc tttatttata tgtcttattt cttcatctat
     2401 tttgatttca tttgtaatat catttaaact tattaagtaa ttgctttcat ctttattatt
     2461 acttaaactt aacaaataaa ttttaccatt taactctact aatttatcaa ttatacttat
     2521 atcgttatca aatttcttca atttttcagc aaccttttca tcttccttta taaaagttaa
     2581 tattttataa taattatcca tatcctttga aaattcatct ttaaatttat tatttgtgta
     2641 acttatatta aagtcatagt ctgttactat ccatacattt ggtattgtgt ccagagcttg
     2701 tctaagtaat tcttttctct ggtctatata gttttttaat tttctttgta taatcatatc
     2761 cttttctatt actaaattta tctttcctaa ttgctctgac tttttactta attttttatt
     2821 tattgaatca agttcgtaat atggatacac taccctattt ctaagactat atacatatac
     2881 ataataagta tggttacata ataataaata tattactcct ataaatctat ttgaatctac
     2941 tatattaatc ttataaattg ctacaaagcc tataatagtt gtaaaaaaaa taaaatatgt
     3001 taaatctttt attaacttat agtgctcaat gttactatca agcttattca acaaatatag
     3061 taaattaaac aaagatatac aaacattaat taatacaata atcatattcc agttaatatc
     3121 tctaaaaata tttcttataa agtaatctaa tatcacaaaa gcactataaa aaattaatat
     3181 tgggcttatt cttagttttt ttactttaga aatagttaag tatataaaag tagacatatt
     3241 aattatgctt aaattgagca acacaatttg gaatttttga atttttaaat ttactactcc
     3301 taaaatactt acaaaaacta atacaagaca ccctactttc aatatattta taaattcatc
     3361 tgttttaaag ttacttatat aaactataga atacccaaat atccaaagta aaattattct
     3421 atacatattt atagaaactg tatacaaact tatatttaaa agtgcaataa ccaaaaataa
     3481 cccattagct agtatataga ccttattctt acttaaagtt cccttagatt ccatattccc
     3541 caccacttct tcatttttat atagttttac ctataaatat gttaccacaa ttcttccaaa
     3601 aaatttgtca ctttctagtt ataaaaaaaa atgagtaaat atttttaatt ttactcattt
     3661 tgtagatttt gtatattcaa tttaaaaagc tggaactata cttcctttgt attcgtcttg
     3721 tataaatttt ttaacttctt tactattcat agcctctgac aaagccttaa tcttatcact
     3781 atctttatta ttttctctac aagctattat atttacatat ggagaatcac ttgattctat
     3841 tactattgca tccttagtag gatttaaatt agctgttaaa gcataattag aatttattac
     3901 tgctccatca acatctttta atactgttgg taattgctct gcattcattt cttttatttg
     3961 tatattttta gggtttttag ttatatcttt tttagttata agctcgccat cttttacctc
     4021 tatcaattta ttttttgcta ataatttaag tgctctagct ccattagttg catcatttgg
     4081 cacagctata acagctccat cttttatttc atctaatgct ttaacttttt ctgaatagaa
     4141 tcccattggc tctatatgaa ctttagatgt ataagtaagt ttatatcctt tctccttcac
     4201 agtttcctct aaaaatggaa tatgttgaaa gaagttagca tctaaagacc cttcatctaa
     4261 agctgtattt ggaagtacat aatcatcaaa tatttttact tctaaatcgt atcctttttc
     4321 ttttaacaac ggttttgcta cttccaatat ctttgcatgt ggatttgatg aagctcctac
     4381 tagtattttt ttatcctctt tgtttgagca acctactgct gatattgcta ttgctgacac
     4441 caatgctact gataataatt tctttaattt cattttttac tccccctctt taaaatgttt
     4501 ataattaatt tattttagtt tcttataagc cagatttcct actccctgga ttatctgaac
     4561 taatattaca agtgctatta cagtatatac cattactgct gtatcaaatc tttgatatcc
     4621 ataaataagt gctatattac ctagtcctcc agcccctact gcacctgcca tagctgtata
     4681 accaagtata gatattattg ataatgtaat tccagatact attgaaggca tagcttcctt
     4741 tatcataact ttaaatacta tttgtctttt tgtagcacca aaagattttg ctgcttctat
     4801 caatccttta tcaacttcat ttaatgagct ttctataatc ctagcgataa atggtgctgc
     4861 cccaatagtt ataggcacta ttgcagcagt ttcccctatg cttgttccaa cgattaatct
     4921 agttattgga atcattgcaa ctataagtat cataaatggg aaacttctaa atatatttac
     4981 tataaatcct aatgcactat ttattgcgct atttggtttt aatccatctg gttttgtaac
     5041 tactaatatg attgccaata taaatcctaa tattgttgcc actatagttg gtactataac
     5101 catatacaaa gtttgtaaca atgcatttgg aaatagtgtt gttaaaaagt caattaaact
     5161 attcatttat catttcctcc catcttatgc ccttactagt cagatattgt tttacttgtt
     5221 cgccactttt atccgaaata tttataataa gtgaacctaa aatatcatct ttaaattgtt
     5281 ctaatttccc aaatattata gacacatcta tatttagttc tcttgccata gtcgtaataa
     5341 tagcttcatt agaaatatct ttagggaata gtatctttat atttgttcct tttggtaata
     5401 ttatactttc ttctcctatt aattttctaa gacctttagt atttcttaag aatatttctt
     5461 ctgtatctcc tacctctaat acttctccat tttccattat tgctactctt ccacaaatct
     5521 gctttatgac ctccatttga tgggttacaa ctattattgt tattcccaat tttttattta
     5581 tatcttcaag caatgaaaga attgattttg tagtatttgg gtctaatgct gaagttgctt
     5641 catcacaaag aagtacctgt ggatttagtg ctaaagctct agcaattgca actctttgtt
     5701 tttgaccacc acttagattt ctaggtttat catttttctt ttcagatatt ccaaccactt
     5761 ctaataactc taaaactctt tttttaattt ctgcctttga atatccaaaa cactctaatg
     5821 gcaatgctac attatcaaat acagttcttc tttcaagcaa tgaaaaatgt tgaaaaatca
     5881 ttcctaactc ttttcttaaa tctctcattt gcttttcatt caatgatttt acttctttgt
     5941 cagaaacaag tacattacct tcttggtatt cctctaatcc gtttatacat ctaagtagtg
     6001 ttgatttacc tgcaccacta tgacctatta ttccaaaaat ttctccagat tctatttcaa
     6061 tactcacatc tttaagcact tgaatctttc cataatactt attaacattt tttatgctaa
     6121 tcataaaatt tcctcccata tattctgctc agtttttatg tttatcctag cttatgtatt
     6181 acaacaaaat aaaagcccga gtataaactc aggcttagaa agctatttat actcatctat
     6241 caactatatt agttgcagga tttagcacca atgtatacaa aatatactgg ttgccgggtt
     6301 tcaaagggcc agtccctcca ccactcttga taagacgtta tttaatttaa ttctattatc
     6361 atttgttgct atgttatata taatatattc attaatagta tttgtcaata aatttattta
     6421 aattttttat tttttattat tgttaattaa ctatttttaa ttagttttct agctcctaac
     6481 actttatatt ttaatgtcta tctaactata gaacatcatt ataagaaata tgttaaatag
     6541 tatcaaatgt ttaagttcta taggctctat tattgtagca tttttcccaa aggttaaaaa
     6601 atattcagcc acccaattaa gtgtagattt tggtatatac atatctatgt atccaccttt
     6661 agacaaaatt ttcaatcctc ttgccaacaa aaattctgtt tcacaatgtt ttactccctc
     6721 atctgccaaa ttaattttaa tacgataatc tgtgcctact tccatattct taaaataatc
     6781 atgtatagaa gataaaacat tatatttctt atttgataag ttttctatac tcaaaatctt
     6841 cacaattctg tctgcacgaa attccttaat agattctgat tttatgcagt aagctggaca
     6901 ataccaaagt ccattcatgg catacaaacc aatagggaca atggtacgta tactattttt
     6961 ttgctttgat gaatattcaa ttttaattgt agattcattc attactatat taaacaattc
     7021 tttcaataat ggtgttgaac aatgcatatc tggtgtccaa aaaacaaatt tacgcctcat
     7081 attctcaata ttatattaaa tatcatttgg tatacaattt aatttttttt aaaacagaaa
     7141 tagtttcttg ctcaaacggc aaatcactat aagatactat taaggctgat gatattatca
     7201 aatattgtct atcaaactta gatgatgttg tactaatgaa tagttgttgg gaacgagcag
     7261 tttactgcaa tcctaatggt gttttaaaac gaggagtata tgttcttacc attaaagaaa
     7321 aagacagtaa taatgataaa gattcgttgg ttaatcgttc aaatgtatac cgtgtaaata
     7381 tacgattaaa aaaagaaact tttactgaaa tgtttggata cattccaaag cgtccaggtg
     7441 taggtcaaat agttgatatg gattttgatt ttacaaaatt ggatatagtc atgccacatc
     7501 ctatctactc atggatggga tgaatatgca tcctaagccc tactgaaaag acatttaaga
     7561 accttaaaac tttaatagga gaatcttaca attttgcaaa agaaaaattc aaaaagagaa
     7621 aaaacaagta aaaacatatg aaaataacct ctaaataaat tataataaaa atattaaggt
     7681 tacaagataa aaaattaata tcttaataat atacaaaaaa gcgaagccaa aaaatgtatt
     7741 atttataagg cttcgctata tctcaaataa tttatttcaa attttaaaac tatttattct
     7801 attatttctt attatttcct gttattccta atctatcatt catatctttt atcatttttc
     7861 taaaaccact acctatatca tttccaacat cttcagttcc atgaactaat tttataaagt
     7921 cattttgact ttttttcata tcttcatcag atactttatc taatttttct attctcttat
     7981 ctatatcttt tactaatctt tccccttcag tgattaggtc atcattcatt ttctttaact
     8041 ctgtatcttc tgttttacca tcttttttaa gagatgttac aaatgattgt attttatctc
     8101 tactatcttt atatgcagcc tttacatcac ttagatattt ttcatttcct ggatattctt
     8161 tgtctttaaa ctgattattt atactttctg gagtatcata aatagagtat ctatttagac
     8221 ctgctatata atcattatag cttgttgaat aataattcat atatccttca ttattattta
     8281 cagattcatt aggatttttt cctgcatttt catttggttt ttcattattt ctagtacatg
     8341 cagttatacc tatagctaat actaatgcta atcctacaaa taaagttctt tttaatttca
     8401 tttttattac cctcctagat g
//
LOCUS       DAMKOJ010000126         8256 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000126 DAMKOJ010000000
VERSION     DAMKOJ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8256
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.135"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..1579)
                     /locus_tag="PC592_003311"
     CDS             complement(<1..1579)
                     /locus_tag="PC592_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF4057241.1"
                     /translation="MMFKIFNKSLLKLVAILSIVLIISNFSLSSYASEITSRTDNVLI
                     VYDSKKETDYNRDILNIMRTLLGRFSSDIKLLKLSNYDGEINKNYYSHIFILGINENS
                     YDNDNKTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYIGKTNNIVSVNYRGKSY
                     NLEEHYIFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKRFDKGRIFVRIEDVHAFRDPKDLVNIADYLSSKDIPFTIALIPAYVNPK
                     NHKITTLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLSGLRVCIENGIYPLAFEAPHYAMESDGYKELKKYFSTYMGQHQNNN
                     KKFSTNTYPYIIRDTEEFNILIPENLGYIDPEDKFTFQHIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDRDLEE
                     NIKSDIRFKSISNISKIL"
     gene            complement(1569..2417)
                     /locus_tag="PC592_003312"
     CDS             complement(1569..2417)
                     /locus_tag="PC592_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4057242.1"
                     /translation="MNIVNKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSIVGLITSSIIIFMYTSYILYNNITYNMDVEFISYMWIIAIPISSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGESKTNKIVKYIGSNIIECTRNEDIIYSLQKDMLGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYRDSFGDSINFKNIVEE
                     ELQYDV"
     gene            complement(2676..3728)
                     /locus_tag="PC592_003313"
     CDS             complement(2676..3728)
                     /locus_tag="PC592_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF4057243.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPIDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITENPVAYPSKEVLNKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            complement(3728..4402)
                     /locus_tag="PC592_003314"
     CDS             complement(3728..4402)
                     /locus_tag="PC592_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057244.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGTK"
     gene            complement(4507..5343)
                     /locus_tag="PC592_003315"
     CDS             complement(4507..5343)
                     /locus_tag="PC592_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057245.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYIKVFGRSILLAGGATLICLVVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            complement(5345..6388)
                     /locus_tag="PC592_003316"
     CDS             complement(5345..6388)
                     /locus_tag="PC592_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057246.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKESN"
     gene            complement(6407..6946)
                     /locus_tag="PC592_003317"
     CDS             complement(6407..6946)
                     /locus_tag="PC592_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057247.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            complement(7382..8071)
                     /locus_tag="PC592_003318"
     CDS             complement(7382..8071)
                     /locus_tag="PC592_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057248.1"
                     /translation="MLQKVLWKFLKLVFGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLILLAVGMVFYMGSGLGSGPRDGLMVALQKKTGKSINLIRGIIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAATQNIVK"
BASE COUNT         2731 a         1464 c          813 g         3248 t
ORIGIN      
        1 ttaaaatttt actaatatta gatatagact taaatctaat atcactttta atattttctt
       61 ctaaatccct atcataattg actataatct catctccatt atttcttatt tgtatttcat
      121 caacttttac ccaattatta aaatctctta aattcataaa ttctatattc tgtttttcta
      181 aatattctat cgtgtttttt agatactcta tgttcaaata tgaatggaag aaaaaacctc
      241 cactaaaacc tcttacaata gataatttat ctaaattttc ttttatatgt tgaaaagtaa
      301 acttatcttc tgggtctata tatcctaaat tttcaggtat aagtatatta aactcttctg
      361 tatccctaat aatataagga tatgtatttg tactaaattt tttattgtta ttttgatgtt
      421 gccccatata agtagaaaaa tattttttta gttctttata tccatctgat tccattgcat
      481 aatgtggcgc ttcaaatgca agaggataaa ttccattctc tatacatact ctaagaccac
      541 ttaaaactct atctttgaca aatatcttca tattttcttt caaaggctca tcttttttac
      601 catcccaaaa ttcatatcct tctccagaaa cttcttcttt cttatattga tgagtatatc
      661 catgcaatat tacagttcca cctttatctt gcatatattt tattgctttg acaatttcag
      721 ggctttctga taaagttgtt attttatgat tttttggatt tacataagct ggtatcaatg
      781 caattgtaaa tggtatatcc ttactactta aataatcagc tatatttaca aggtcttttg
      841 ggtctctgaa agcatgtaca tcttctattc ttacaaatat acgtccttta tcaaatctct
      901 taatattaaa aatatcgtta agtgaatcgc aaaatatata aaataaaaca ccatctaaat
      961 ctaatttcga tacataaaaa aggtttttat catttattat atatggatac ttatttaagg
     1021 tatcattaat acttcctatt actttattac ttgtatcttt tgattctaca atgttaaaaa
     1081 tataatgttc ttctaaatta tatgatttac ccctataatt tacactaact atattatttg
     1141 tttttcctat atagtctaaa ttgtattttt tatgttccaa aagattctct ataccatatc
     1201 ctagccaaca tatagttcct ttatataaat ttaaagaact aatcaggttt ttagttttat
     1261 tatcattatc atatgaattt tcattgattc ctaaaataaa tatgtgactg taataatttt
     1321 tatttatctc accatcatag ttactcaatt ttaatagctt tatatccgaa ctaaatcttc
     1381 ccaatagagt cctcataata tttaaaatat ctctattata atctgtttct ttcttagaat
     1441 catatacgat taatacatta tctgttctag aagtaatttc tgatgcatat gaagatagac
     1501 taaaatttga tattatcagt actattgata atatagctac taactttaac agacttttat
     1561 tgaatatttt aaacatcata ttgaagttcc tcttcaacta tattcttaaa atttatacta
     1621 tctccaaaac tatccctata ttgtaaaaat gcaattttga catctatatt tacatatttt
     1681 cccctattgt ttaaatctaa atttagttct tttatccttt tctttattct gtctttaaca
     1741 acttttgaac cttccaaaga tgtatttggc attagtatcc ctagcatatc tttttgtaaa
     1801 ctatatatta tatcctcatt ccttgtacat tctataatat ttgaaccaat atattttact
     1861 attttattag ttttgctttc accaaatata gtctgtaggt ttccatagta tggtaatttt
     1921 actatcataa gagaaaaatc agtattatgt ctaatagatt tacttatctc catatttaca
     1981 tcattataaa aaatctttaa atttctaagt ccagtttcac tatcaatagt cactaattcc
     2041 ttatactgtt cagatagttt tttatttgtg ttttgcaatt catttatgct tttgttcaga
     2101 ttacccatta taattgaaga tattggtatt gctattatcc acatatatga tataaattca
     2161 acatccatat tgtaagtaat attgttatat aaaatatagg atgtatacat aaatataatt
     2221 attgaacttg ttattaatcc cacaattgag tttgacaaat aagttaacat tattataaaa
     2281 aaaattattg ctagcattat aaacacattc aatttatttt ctgtcctaat ggatagtatt
     2341 actattccaa caattaaaaa tataaaaacg agcaaagcca atattaataa atctattttt
     2401 ttatttacaa tattcatttt ttataaattt acacctccaa ttattctatt aagttgccca
     2461 ttctttctaa ttattattaa agtcattata caaataagtt ttcatttatt aacaaagtat
     2521 ttaaattgtg tatgaatata acttaataaa aaaatactgt ctcaaagtaa attttttaac
     2581 tcataaatca ctcttttttg tacgaaatcg aatatgtttt caacaataaa aaagaggctt
     2641 atctcaattt cgagacaacc tctttatagt tattattatt ttgattttaa ctctatccaa
     2701 gccttatcat ataattttat attttcacca atatcttcaa aagtttcaca tttattaagt
     2761 acttctttag atggatatgc aacaggattc tcagttattt ccgggtctaa taattttaga
     2821 gctcctgtat taggtgttga ataccctatg tactcagcat ttacttttgc attctctggg
     2881 tccaataaaa agtttataaa caactcagct tctttcttat tttgtgctgt tgtaggtaca
     2941 cacatagcat ctacccattt attagttccc tctttaggta tagcataatc aaggtcagga
     3001 ttttgttcca ttagtgtaac tgcatcccca gaatacagca tacccattgc cacttctcca
     3061 ccaagcaatc tatccttgcc ttcatcattt acataagcca atactaaatc cttttgtttc
     3121 attaaaagat ttttagcttc atttatttcc tttggattta cactgttcat gctatatcct
     3181 aattttttaa gagttattcc tatagtatct ctaacagagt caaacatcat tatatttccc
     3241 ttatactttg gattccaaag tatattccag ctatcaatag ggtctttaac ttctttctta
     3301 ttgtacaata ttccaagagt tccccacata tatgcaacac tatattcatt agttttgtcg
     3361 tatacaggat ttaaaaaact cttatctaaa tacttcatat taggtatatt cttaaaatct
     3421 aatttttcca aaagaccttc atttttcatt ttctctacca tatagtctga aggaaatact
     3481 aaatcatagt gtgtactacc actttttacc ttttgataca tcatttcatt agtatcataa
     3541 gttgaatatt gaacatctat tcctgtttct ttttcaaact tatctataag agactcatct
     3601 atataatctc caacattata tacatttaaa acttttgtag aatctgttgc tttattacat
     3661 cctgtaaata aagtaactgt catcatacct acagctataa gggatattgc ttttttaaac
     3721 ttaatcatta tttagtcccc cttactatag attctttttt attagccagt aaaagtaacc
     3781 ctagaacaac tgcaaacatt attgttgata atgcatttat ttcaggtttt atacctcttc
     3841 tagccattcc atagatttct atagaaagat tgcttacacc atttccagca ttaaagaaac
     3901 ttattataaa gtcatctatt gacatagtaa acgcaattaa aaatccagaa actatacctg
     3961 gttttatttg tggtaaaatt acttttctaa gagcgtatat aggtgttgct cctaaatcca
     4021 tagctgcatc ctctatatta tcaggtaatt gcttcatttt tggcaaaact gaaagtataa
     4081 cgtatggcaa acaaaacatt atatgtgcta ataacattgt tgtaaatcca aattccattt
     4141 ttacaaatac aaatagactc ataagagcta ctgctgtaac tatctctgta ttcaaaatag
     4201 gaagatagtt tacatttagt attaatttct tactcttacc tctcatctta tgtattccta
     4261 tagcacttat agtccctact attgtagata ttacagacgc caatatagct attacaatag
     4321 tataatataa agcactcatt atactctcat tttgaagtaa ttgaccatac catttccatg
     4381 taaatccatt ccatcttgcc attgattttg aatcattaaa agaaaatagt accaaagcaa
     4441 atatgggtgc atacaaaaat aagaatacta atgctaaata tatattagaa gttattttct
     4501 ttaattttaa aatagtaacc caccgccttc tttgtcagat tcatctccaa attttgacat
     4561 tatagacata gatattaata ttactatcat cataaatatt gatatagctg aaccaaagtt
     4621 ccaatctcca acgactgtaa actgttgctc aatcaagtct ccaaccagca tgattttacc
     4681 tccacctaac agtcttgata ttgcaaaagt agtgactgcc ggcataaata ccatagttat
     4741 tccagacatt acacctggca aactcaaagg aaatataatt tttctaaaca ctgtcatatt
     4801 atttgcaccc aagtcatgag cagcgtttat caaatcatta tccatctttg acagtgctgt
     4861 atatattgga agaaccataa atggtaaaaa gttatacacc atacccaaaa gtatagcaaa
     4921 gttagtatac aaaattgcta atggttgtat tccaaaccaa cctaaaaatg tatttaaaag
     4981 tccatttttt cctaatatag caacccatgc atatgttctt aaaagaaagt tcatccacat
     5041 aggaagaata aacaataata ttaatgaacc tcttctgctt acacgagcct ttgaaattat
     5101 atatgccaca ggataaccaa ctacaagaca tatcaatgtc gctcctcctg ctaaaagaat
     5161 agaacgccca aaaactttta tatatatagg gtcgattact tctttatagt tctcaagtgt
     5221 aaaagcataa cctccacctg attcttttgt aaaactaaaa aataccacta gtattaaagg
     5281 aattattaca aatatcgcac tccaaactac atatggatat gctaaaaaag attttctttt
     5341 catcttagtt actctctttt ctcattatat ggatatcttc tggatatata tccatgccta
     5401 gttcagtccc aacctcagca tttttagtat tatgaagtat ccacaatctt ccattttcat
     5461 tcaattctat ctcgtaatgc actcctttaa acactgtaga tgtaactttc ccctttaaca
     5521 ttccttcttc tggctttacc atttttatat cttctggtct tattactacc tctatatttt
     5581 cgtttttttc gaatccttta tcaacacact caaaatccct attacagaaa ttaactttat
     5641 aatcctctat cataattcca tcaaatatgt tactttcacc tataaactta gctacaaatg
     5701 aatttttagg ttcattgtat atatcttgtg gtgttcccat ttgttgaatt tttcccttat
     5761 acattacaac aatagtatct gacatagtaa gagcctcttc ttggtcatga gttacaaaca
     5821 caaatgttat tcctaatttt ttttggattc tctttaattc tatttgcatc tcttgtctta
     5881 attttaaatc aagtgctcca agtggttcat ctagtaacaa tacttttggt tcattgacta
     5941 gagctcttgc tattgcaatt ctctgttgtt gtcctccact caatgattca acttgtcgtc
     6001 tttcaaaacc ttctagtgca acaagtttca aaacctcttt tactttagca tctattacat
     6061 cttttggagt ctttttaatt tttagtccaa aagctacgtt ttcataaaca tccatgtgtg
     6121 gaaataaagc atatttttga aatactgtgt ttacttgtct ttcatatggt ggcaaattat
     6181 ttatctcctt accttcaaat aaaactttac catcatcagc atactcaaac cctgctatta
     6241 tttttaatgt tgtagttttt ccacatccac ttggtccaag taatgttaaa aactcatttt
     6301 tctttatatc taaattgaaa ttatctaaaa cagtaagttc ctcataatgt ttagatatat
     6361 cccttaattc tattatattt tctaccaatt attaaacacc tctattctaa aatgatggtg
     6421 gcgtacttac ccaaatcact tttgctgtag ttttgccttc gtttgatata tagtgatttg
     6481 ctttcggtct aaagtaaaaa ctctctcctt tttttacttt atttttcttt tcgcctatat
     6541 ggacgtatat tgaacctgct aatacatatc caaattcttc accttcgtgt ggcttttctt
     6601 ctttatactg tcctcctgga tacaatgtta ttattattgg ctccatttca tttttttgtg
     6661 aatttggaat taaccacttt aatttatatt ttaagtcttc atcttcagtt tcaaacatat
     6721 cttcttttgt aaaactgatt ctttcatcat ctatttcatt aaaaaattcc cttaaatttg
     6781 tacctagtat ttcaagtata tctataaggg tagctatgga tggtgatgtt aagttatttt
     6841 ctaattgaga aataaatccc tttgacaatt cacatctatt agctaactct tcctgggtca
     6901 gttgtttttc tgttcttaat ctttttatct tttcacctat atccatgttg cacctcctag
     6961 tttctgtttt attttactaa acattttgtt tactaaacat tgagtttaaa atttctaaac
     7021 aacataggta attatatata aaatttggat ataatacaag agtttttttg acattttttt
     7081 atttttttat ttagaataaa tacaagcatt ttaaaggctt tggaaaatac acagtttaaa
     7141 ggtgtttata ttaatatcta taaagtttag tatctctaat tataaattaa ttcattcatt
     7201 aaatagagaa taagacttct aatactaaaa aaacattgaa caaataaaaa attgctagaa
     7261 atctatattt tatagtgttc tagcaatcct tatattttaa tattctttta atatttagtt
     7321 tatatctcta aacaaaattt taatttaaaa tacctaacat ttcgttgaat ttatttttaa
     7381 attacttaac tatattttga gtagcagctt ttttctctcc actcatatac actttgataa
     7441 attttatatc atctactata aatctatgtt taatcttact acaatctaat ttaaataagc
     7501 caaataccat ttgtgtaaaa taccccaatc caaatgcact tattatagtt cctataccaa
     7561 cttttccacc taataaaaat cctactatta atgctccaac ttctataata cctcttatta
     7621 agttaattga ctttcctgtt ttcttttgaa gtgcaaccat caaaccatct ctaggtccac
     7681 ttcctaaacc acttcccata taaaagacca ttccaacagc caaaagaatt aatcctaata
     7741 tcaacataat tattcctaca aataaactat cagcctctgg aattaaattg ctatataaaa
     7801 gtaaatccat aaaaaatcca attagtagca tgttaaaaac agttccccat cctacatttt
     7861 ctccaagaac gacatcagca ataactacta tagaacccac aattatagag gcagttccta
     7921 tagttattcc tatatgattt gaaagtcctt gatgaaatac atcccaggga gataagccaa
     7981 ggttacaatt tatcgtcaat actataccaa ctgaacatat aaataaacca aacactagct
     8041 ttaaaaattt ccataatact ttttgcaaca aattctaccc ctcctaaaca taatttaact
     8101 actcactcta aatatcgaaa gccagcagtt ttctcttgaa ctactccaca ttaactatct
     8161 tatgtgatat ttaaatctgg agatttctat taaataatac acttctatga tacatcattt
     8221 tatgctaaat aactaccatt ttattacaat ttagtt
//
LOCUS       DAMKOJ010000127         7983 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000127 DAMKOJ010000000
VERSION     DAMKOJ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.136"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            203..1354
                     /locus_tag="PC592_003319"
     CDS             203..1354
                     /locus_tag="PC592_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDF4057249.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     GIKEVRQDVAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKSAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVNNLKNTLKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSHV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1400..2575
                     /gene="thiI"
                     /locus_tag="PC592_003320"
     CDS             1400..2575
                     /gene="thiI"
                     /locus_tag="PC592_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDF4057250.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGKFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIDA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDKINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2711..3514
                     /locus_tag="PC592_003321"
     CDS             2711..3514
                     /locus_tag="PC592_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF4057251.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEEPSKDKNKVIKDVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGGESIAKVYVTCTEHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKSNDDFRKY
                     LLDNKYKKGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKPDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3757..4398
                     /locus_tag="PC592_003322"
     CDS             3757..4398
                     /locus_tag="PC592_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF4057252.1"
                     /translation="MINNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKAISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDVGILTGNITTAAQALGLGSCIIGMIRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYREILDIPEGYSVPFGIAIGIPDGNLPNAREVVYKVSRV"
     gene            complement(4797..5531)
                     /gene="pflA"
                     /locus_tag="PC592_003323"
     CDS             complement(4797..5531)
                     /gene="pflA"
                     /locus_tag="PC592_003323"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDF4057253.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSDGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDVDNLEKLGKFVATLKNVERFELLPYHSMGIHKWENLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(5691..7922)
                     /gene="pflB"
                     /locus_tag="PC592_003324"
     CDS             complement(5691..7922)
                     /gene="pflB"
                     /locus_tag="PC592_003324"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDF4057254.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDKAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
BASE COUNT         2920 a         1067 c         1324 g         2672 t
ORIGIN      
        1 taatgtattt ttgtagggta tagtataagt atattatatt ttactataaa aatttgtaat
       61 aaagtgaaga aactagcttt tcatgaaata atattttata atttaagatt gtctttttaa
      121 taaagattaa caaaaaaaat actataatta atggtataat agttagagtt gaagatttta
      181 aataaaggta ggtgtaatta agttggaaat atacttagac aatagcgcaa ctacaaaacc
      241 ttatcaagaa gttatagata aaatggttta tgcacttaat acggaatatg gaaatccttc
      301 ttctgtccat agaaaaggtg tagaagttga aaagggtata aaggaagtaa gacaagatgt
      361 agctaaatct ctaggagcga aagaaaagga gatttatttt acatcaggtg gtacagagtg
      421 caataatact ataataagag gtatcactag tctaaataaa aaaagaaaaa atcacataat
      481 atctactaac atagaacatc cttctgtgtt aaatacatta aaagatttag aagaagatgg
      541 ttttgaagta acttatttag aggtcggaaa agatggaaaa ataaatatag aggatttaaa
      601 aagtgcgata aagtcaacta catgcttagt aagtatgatg catgttaaca atgaaatagg
      661 gactatacag ccaataggag aagtcggaaa gtatttgaaa ggtttaaaag aaaagattta
      721 tttccatgtt gatgctattc agtcatatgg aaaaattaac tttagaccat ctaaatataa
      781 tatagatttt atgagtgtaa gtgcacataa attccatggc ccaaaaggaa ttggatttat
      841 gtatataaaa gaaaataatc gccttaagcc tatgttaaca ggtggtggtc aggaaattgg
      901 aattaggtcg ggaacagaaa atgtacctgg gatatatggt cttggagaag ctgttagaat
      961 actgaataaa gatttagatg ctgtcatttc gaaagtaaat aacttaaaaa atacattaaa
     1021 aaatgaaata attgataata tagaagatat aaaaattaat tctcctgaag atggagtatg
     1081 tcatatatta aatgtatcat ttagagggac aaaaggagaa gttttacttc attacttaga
     1141 gcaaaaaggt atttatgtat caactggctc tgcatgctct tctaaaaaga agggtagtca
     1201 tgtattaaat gctataggtc taacaaatga agaaataaat ggaacaataa gatttagttt
     1261 atctgatatg aacacagaag aggaaatgtt agaagctgtg aaagttttga aagaatcaat
     1321 ttgtgactta aggtcaataa tgaaaagaaa ataaagaata ctgtataaat agtgagaata
     1381 aattagttta agaggtgaaa tggtgtataa tatattaata gtaaagtatg gagaaattgg
     1441 agtaaaagga aagaatagat atatatttga gaataggctt ataagaaata taagaaatat
     1501 gttaaagcca attggcaaat ttaatgtata taaagagtat ggaagaatat atgttgattt
     1561 agaagattat gattatgaag aagtaattga agaagttaga aaagtatttg ggatagttgg
     1621 tgtatgtcct ggagtaagag ctaaaaaaga ttatgataca ttaaaagaaa tagctttaaa
     1681 aatgttagaa gaaaaaatag atgctggata taaaactttt aaggtagagt caagaagagg
     1741 agataagtct tttgggttga cttctcaaga aatgagtatg gatataggtg gatacttatt
     1801 atcaaaggta ggagataaga ttaatgttga tgtaagaaat ccagaagtta aaataaaatg
     1861 tgaatacaga gaatttcata ctatggtcta tagtgatact atacctggat atggtggatt
     1921 gccacttgga acgaatggta gagctatgtc tcttttatca ggaggtatag atagtccagt
     1981 agctacatgg atggttgcaa aaagaggtat ggaggtagag gcagttcatt ttcatagtta
     2041 tccatttaca agtgaaaggt cacaggaaaa agttaaggat ttagctaaaa tactggcaaa
     2101 atactgtggt agagtaagac ttcataaagt taatatatta gaaatacaaa aagcaattgg
     2161 tgagaattgc aatgaagaag aagctactat tctttcaaga agatttatga tgagaatagc
     2221 acagagactt tctgaaaaaa gacattgtga tgctttaatt acaggtgaaa gcattgggca
     2281 ggttgcatct caaactatac aaggtcttac ttgtactaat gccgttgtag atttaccagt
     2341 gtttagacca cttatagcca tggataaatc agatatagtt gatatagcaa aaaaaatagg
     2401 aacttttgaa acatctatag tgcctgaaga agattgttgt agtgtatttt ctcctagaaa
     2461 gcctgttact aaacctagat tagagaaaat agaaaaatct gaaacagcac ttgatattga
     2521 aaaactagta caggatgcga ttgacaaaat agaggtagag gatattgagt tttagtacaa
     2581 aagttattta attattaaat tgaatattga gcatattggt agttctgttg aaaggactta
     2641 tatagacgat ttattaatat gtagtattta aaaataagta ctataatttt atttaatggg
     2701 aatgattatt atgaataaaa agggttttac actaattgaa ttgttggtag ttatatctat
     2761 aataggaatt ttagttatag tagctgttcc agcgttattt agaaatatag aaaaaagtaa
     2821 ggcggttaca tgcctttcta atagagaaaa tataaagact caaattgtta ttgcaatggc
     2881 tgaggaacca agtaaagata agaataaagt cataaaagat gtactagaaa ataaagatgg
     2941 taagtacttt gaaacagaac caaagtgtaa atcaggtgga atatattcag caacgtttga
     3001 tgatggttat gatggaataa ctggaggaga aagcattgca aaagtgtatg ttacttgtac
     3061 agaacatcca gacggtgttg aaatggctag ggatgtacat caaagtatga aagatttgat
     3121 tgcatcattt gcacaagacc cttctataat accaggagct tcaaagagta atgatgattt
     3181 tagaaaatat ttattagaca ataaatataa aaagggatgg cctacaattc cagatgaatt
     3241 taaagcaaaa tatggattaa gtaaggatac actatatata caaccatatg catataatcc
     3301 tactaaacct gatgccactg tagttgtatt tgcaaataat aagactggag gtaattggta
     3361 cacttcccta gtttacgatt atgatgaagg tagatggtat aaaggcaaaa atggtatttc
     3421 tgttgcaggt aggtcatggg atgttgatac agatagtgtt aagtctgtaa aaacagagat
     3481 tcattctaaa gagggatggg gtcctttaaa ttaatatata atgttttatt aatctggtat
     3541 tgattaaact atagaaaaga gcagtttcta tagatgacga ataccagatt tttatttata
     3601 tgtataatta atatatatta aaagtattta tatttttaag tcttcacatg taagctaaaa
     3661 ataattataa taatgttgta aagaagttta actacaagat taattttctg aagatttagt
     3721 atttatacta agaaatacac aaaaagggga atagatatga ttaataattt tcaagacaac
     3781 caaacaataa atttaataca aagtcgtaga agtatacgaa aatttacaac agaacaaatt
     3841 agtgatgagc aagtaaacac attattacac tgtgcatttg cagcaccttc aggatgtaat
     3901 aaacagcctt ggcacataac tgttgtgcaa gaccagaaac ttttaaaagc gattagtgat
     3961 gatactttat ctaggattca tgaggtgagt aatgttgaga taaataaaaa ctttaagtta
     4021 ttttatggtg ctccaactgt tttatttatt tcttatgatg aaagtagctc atgggctcca
     4081 tatgatgtag gaatacttac agggaatata acaacagcag cacaagcact agggcttgga
     4141 agttgtataa taggtatgat tagaggatta tttacacctg ttgaacaagg agatattgaa
     4201 ggtcttgtga gtgtattgga taaagaagat gtaaaagaat cagagtcaat aaagatgaag
     4261 tttgatacaa ataaaaaata cagagagata cttgatatac cagaagggta ttctgtacca
     4321 tttggtattg ctataggtat tccagatggg aatttaccaa atgctagaga ggtagtttat
     4381 aaagtttcta gagtttagga taaagtattg caacaatcaa tcggttattt gaagaattaa
     4441 atcggtaata tccaaataaa ctaatagaag agaaagctat ttaaaaagta gcttagattt
     4501 tttattgtaa aataattaaa taaagaatag ggtgataagt attttattta ttatcctatt
     4561 cttttttatt tgtagaatga taaaaaaatg ataaaaacaa gaattaagtg taatacaatg
     4621 taaataaagt gtgttaattt tgagtatatg ttgtaaagtt tatcaaaact gaaaaactca
     4681 agatatattt tcagtataat agtgtataaa aatagggtaa agtggaagtc tcgaagtctc
     4741 ttaaaaattt gcacttttcc ctattttatt atgttttcta taaaggttaa tatacactaa
     4801 ctattatata ctttcactcc aaatttagag attatttcac tagctttttg aacatcttcc
     4861 ttagtggcat caggaacatc ttttagttca taatcgatac ctaaattttc ccatttgtgt
     4921 attcccatag aatggtatgg tagcaattca aatctttcta catttttcaa tgtagctaca
     4981 aatttaccta gtttttctaa attatctaca tcatcagtaa taccaggaac taaaacatgt
     5041 cttatccata caggaatatt tcttgattct aagtgtctag caagttttaa tgccttatcc
     5101 ataccaacac cagtcaaatc aatagatttt tcctcaacca tatgttttaa atcaagtaaa
     5161 accaaatcag tattgtctaa aactgggtct atagtttcta tatctacgaa tccagatgta
     5221 tccaagcaag tgtgtatatc attttctttt gcttttttaa ataattcact taaaaactct
     5281 ggttgaagag tggattcacc accagaggca gttatacctc catcagaaaa tttcataaaa
     5341 gaagtatact taagagcatc cgttattatt tcatcaactg tatattcttt tcctgattta
     5401 atatcccatg tatccctgtt atgacagtat ttgcatctaa gaggacaccc ctgaaaaaat
     5461 aatatatatc ttattcctgg tccatctaca gtaccaaacg tttctataga atgtattttt
     5521 cccttaatca tagagttcac ctcacaatat attttaataa ccttatcaat agttataata
     5581 tttctctaaa aaaggccatc ttataccaga aataattcaa atataagata gccttttatt
     5641 tttattttct acacagtagt aatcttagtt aaagtataaa aatttaaaga ctaagccatt
     5701 ttaccgtgga atgttctgtt tataacatct aattgttgct ctttagttaa ttttatgaag
     5761 ttaacagcat atccagatac tcttatagtt aattgtggat attcttctgg atgttccata
     5821 gcatcttcta aagtagctct atcaaataca tttacattta ggtgatgagc attttgagcg
     5881 aagtatccat ccatcattgc agaaagattg tttattcttt cagtcatatc ttttcctaaa
     5941 gcagcaggta ctatagagaa agtattagat ataccatctt gagcgtgctc atatggtaat
     6001 ttagcaactg aagataatga agctaaagca ccattagtat ctctaccatg cattgggtta
     6061 gcaccaggag caaatggagc accagctctt ctaccatctg gtgtattacc agttttctta
     6121 ccataaacaa catttgaagt tattgtaagt atagattgag ttggataaga atttctataa
     6181 gttttatttt ttcttatttt attcataaag ctttcaacta actctacagc tatactatca
     6241 actctatcat cattgtttcc gtattttgga taatctcctt ctatttcaaa atcaacagct
     6301 attccttgtt catttctaat agttttaacc ttagcatgtt ttatagcaga taatgagtct
     6361 gcacaaactg ataatccagc cataccacaa gccatagttc taaatatatc tctatcatgt
     6421 aatgccattt ctaatgcttc ataagaatat ttatcatgca tataatgtat tacatttaaa
     6481 gtatttacat ataatgttgc taaccaatca gtgaatggtt caaatttact cataacttca
     6541 tcataatcta agtactcaga agttataggt tcaaatcttg gtccaacttg aacgccagat
     6601 ttctcatcta caccaccatt tatagcatat aataaagttt tagccaagtt aactctagct
     6661 ccaaagaact gcatttgttt accaattctc attgcagata cacaacaagc tataccataa
     6721 tcatctcccc agtatgctct cattaaatca tcattttcat actgtactga acttgtatct
     6781 atagatactt tagaacagaa atctttgaat ccttgaggta atttagttga ccatagaact
     6841 gttaagtttg gttctggaga aggtcctaat gtatatagag tatttaacat tctaaatgag
     6901 tttttagtaa ctaatgttct accatctatt cccatacctc ctatacactc agttacccaa
     6961 gttgggtctc cagagaatag gttattgtaa tcaggagttc ttaggaactt aaccattctt
     7021 aatttcataa caaaatggtc catatactct tgtaattctt cttctgttac gattccagct
     7081 tttaaatctc tttcaaagta tatatctaag aaagtagatg ttctacctaa agacattgca
     7141 gcaccatttt ggtctttaac agcacctaaa taaccaaagt ataaccattg tacagcttct
     7201 tttgagttag ttgctggttt tgatatatca aatccataag attcagccat ttttttaagt
     7261 tcatttaaag ctgatatttg ctcagttatt tcttctctta atctgataac ttcctcatcc
     7321 atacaagaaa cttctaatga tttcttttgc tcatttttat cttctattaa agcatcaaca
     7381 ccgtatagag caactcttct gtagtcacca attattctac ctctaccata agcatctgga
     7441 agacctgtta ttataccaga ttttctagca gctctcattt ctggagtata aacatcaaaa
     7501 actccttggt tgtgtgtttt tctgtattta gtaaatatat cttttatttc tgggtctaat
     7561 tcatatccaa aagcttcgca tgaattttca accatcttga taccaccata tggcatgaca
     7621 gctcttttta aaggggcatc cgtttgtaac ccaacgattg tttctaattc tttatctaaa
     7681 tatcctggag catatgcagc tattccagaa acagtttttg tatcaacatc taaagtacca
     7741 ccattttctc tttctttttt aaatagaacc attgctttgt cccataattt tttagtattt
     7801 tcagtagcac cagctaagaa agagtcattt ccctcatatg gagaatagtt caattgtata
     7861 aactctctaa catttatttc tttagtccat cttcctgttt taaatccttg ccatgcattc
     7921 attaagtatt tcctccttag atttaaatga taaataatac tattaaaatt aatttttata
     7981 tac
//
LOCUS       DAMKOJ010000128         7924 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000128 DAMKOJ010000000
VERSION     DAMKOJ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.137"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..619
                     /locus_tag="PC592_003325"
     CDS             <1..619
                     /locus_tag="PC592_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4057255.1"
                     /translation="LMYLMLILISSLCVIVYSYKITSLYIFKNFKIGILLVFYFLFSQ
                     IIFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSFLQSILFDRFGKKIG
                     IVMVGTCWSLWHLPLQFTLYSPQTPIIGAIAHLIYGIGLSIFLGYVYMKTKNIWFCSI
                     MHVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEYK"
     gene            999..2525
                     /locus_tag="PC592_003326"
     CDS             999..2525
                     /locus_tag="PC592_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF4057256.1"
                     /translation="MNESYWFLNSNPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYRETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMAAVLENKLADGMFISIDDPSITFRQY
                     NDGNENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKKVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            2553..3110
                     /locus_tag="PC592_003327"
     CDS             2553..3110
                     /locus_tag="PC592_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057257.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKLFLVIFLFMFSMGVASLWEIGEFLMDTFIGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSSI"
     gene            3632..4675
                     /locus_tag="PC592_003328"
     CDS             3632..4675
                     /locus_tag="PC592_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057258.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKSIDEEGVV
                     VNIDNEILTKVEVVNDDNEIQEKIIEEDWLISENTLKLDDKEAIINDKDIELCKKEVQ
                     VESEKIDLNKFEELDQNENYNLEKNVIEEKEVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHKQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKN
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYKFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDVLEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            4786..5928
                     /locus_tag="PC592_003329"
     CDS             4786..5928
                     /locus_tag="PC592_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF4057259.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKIKKREVK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKNNYLQVRASHILIKTVDDKGKQVSNSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEIKSDLVSSLTSEKQSLLIQNLKEKYNVKITDKYQMKAKE"
     gene            6386..7777
                     /locus_tag="PC592_003330"
     CDS             6386..7777
                     /locus_tag="PC592_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF4057260.1"
                     /translation="MSSTESVSKKGGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSITMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEE"
BASE COUNT         3184 a          706 c         1351 g         2683 t
ORIGIN      
        1 attaatgtat cttatgttaa ttttaataag tagtttatgt gttattgttt attcttataa
       61 aataacaagt ttatatattt ttaaaaattt taagataggt attttgctag ttttttactt
      121 tttattttct caaattattt ttggattaat aataagtgat aatcaatttg attataagaa
      181 tttcttgaat tatattcttc ttcctataat atcattagta tacatttatc cttttttatg
      241 tgaagagtat ggttggagat cttttttaca aagtatttta tttgatagat ttggcaaaaa
      301 aataggtatt gtaatggtag gcacttgttg gagtttatgg cacttacctt tacaatttac
      361 actatatagt cctcaaactc caataattgg agctatagcc catttgatat atggtattgg
      421 actttctata tttttaggtt atgtttatat gaaaactaag aacatatggt tttgctctat
      481 aatgcatgtt ctaattaata gcttaggatt aattttcaat gattctgaaa taattattaa
      541 ttaccatagt attatacaaa gattgatatt tatactatta ttttatactc cttttctatt
      601 tacaaaagaa tataagtaag aattacaatt aatttatata aaataaattt ttaagtaaat
      661 atttttatag agagattgtt atattacata tcagaaaaat attaaacgaa ctaaatcaat
      721 aaaaaagttg gtggctaaca atttataatt gttagcacaa catcatctta tgtattgaaa
      781 tctaaaatat tctcattttt acttagcata aatactatta attaagaaaa taatatagaa
      841 attataaata tatataagtt tagtctggtg tataaaacaa gaaaactaag tgatttttaa
      901 tttagctttt tattaagctt attttttata ctatttataa taaataaact ccatgatggg
      961 aaaactatta ctatttaata tgtaaaggag tattttaaat gaacgaatca tattggtttt
     1021 taaactcaaa tccaaaagaa tataacaaat taggtgaaaa tataaaaaca gattgtctta
     1081 tagtaggtgg tggaataact ggattgacaa ctgcatattt attagcaaaa gaaggtaaaa
     1141 aagtagtgct tgttgaggct gataaaatag gatatggaac ttctggaagg aatactggta
     1201 aggtaacttg tcagcatgac atattttact ctaagataga gaaaaaatat ggattagata
     1261 aagcaaaatc atattataat gcaaataatg aagctttaaa tttagttgaa caaataatag
     1321 aagaaaataa tataaaatgt gattttaaaa gggaaacttc ttttgtattt acagaaaaag
     1381 aggatactat aaagaatatt aaagatgaat atcgtacatg taaaaaaata ggaataaatt
     1441 gtgagtatcg tgaaactata gaaaatattc cattagatat aaagggggct attagtttta
     1501 ctaatcaagg tcaatttaat ccaaagaagt atattgatgg attggcaaaa gcagcagtaa
     1561 atttagggct aaaaatatat gaaaatacac cagtagtaga ccttgagaaa ggcaaaatat
     1621 gtagggttaa aacaagagag gataatataa tagaagctga gaatgttata atttcatccc
     1681 atagtccatg gtatgatgga ttgaattttt attttgcaaa agaatatgca gagcgtgctt
     1741 atttaatggc tgcagttttg gaaaataaat tagcagatgg tatgtttata agtatagatg
     1801 acccatcaat aacttttaga caatataatg atggaaatga aaatttactg atttttggag
     1861 gaggagacca taaagtcggt cagggaggaa ctgagaaaga aatatttgat gatttagagc
     1921 attatgggaa aaaagtcttt aaggtaaaag attttaaggg gaaatggtct gctcaagata
     1981 atatgagttt tgacaatgtt ccttatattg gttatatcaa caaaagagaa gacaatattt
     2041 atgtagctac agggttctct aaatggggga ttactaatgg aactgctgct ggaataataa
     2101 taaaagattt gataataaat aataattctg attataaaga tacttttaat ccatccagat
     2161 taggtagcta cttttcaaaa gattttataa aggaaaatgc aaacgtagca ataaattatg
     2221 taagtggaaa attaaaaata ggtagtggag atatgcctaa aaataatgga gaaggaaaga
     2281 ttgttaatat tgatggaaaa agatatggtg tatataagga tgataatgga gatttttata
     2341 ttgtagacac gacatgtact catttaggat gtgaacttaa ttttaacagt gaagaaaaaa
     2401 catgggactg tccatgtcat ggttctagat ttgactataa gggaaatata cttgaaggac
     2461 cagctcttaa gccattaaaa ctttatggac atggtgataa tgatgttaat cctaagttat
     2521 tataaaatta tttttaggaa ggtaaagtgt atatgaataa acttttaaag ccaataacta
     2581 tactattgta tatagtttat attttatctg ctgtattttt tgtagcaaac aaagaatatg
     2641 gaagtctagg tctagtagca attagtttag ttggtacttt cattttgagt tttataaata
     2701 agcaaactga aagattattg agtaaagaat tatatataat gcttgcttta tttataatgt
     2761 tttcatcatt attaggtact tgttttaatt tttatgatat aaattattat gatgattttt
     2821 tgcatttatg gtcaggtata atatcttgta ttgtggcttt ttctataatt aaatactttt
     2881 atacacaaag agagataagt aaaatgagta aattgttttt agttatattt ctatttatgt
     2941 ttagtatggg agtagcgagt ttatgggaaa taggtgaatt tttaatggac acttttattg
     3001 ggactactac acaggctgga ggattagaag atactatgat tgatatggta gatgctttaa
     3061 taggtacaat tataactatt ccttttatag taaaaaaatc tagtatatag ttttaaattt
     3121 tttatattag ttataatgga tttaattaat catgttgagt ttcaaggtct atatgattaa
     3181 ttaaatccat ttttgttatt tataattatt attgaatata tttttacata tgagatatac
     3241 ggtgatagat agaaattgtt ggattatgta aataattaat atataatacc attatgggca
     3301 ataaatacaa atcaaatgat aatatagtct atttatgtaa atgttatatt gtatcctaag
     3361 tataatagta agttttttga taatggtgta gaaagtaaaa atctactagt ctaaattgat
     3421 gtatggatta gtttaggaac agtaattgca tatcttaaat ttgatgtcat gttgagctac
     3481 tagaaatagg tcatcttttt cacttgaata tcttttcttt aaacatgggg agtatcatat
     3541 caaaaacata tgaaaattaa gtgatttata agaacagtaa tattttatat gatagtatag
     3601 aatagtaata aagtattagg aggaacattg agtgttaaaa aagtggtttg gtattgtgaa
     3661 aaaaagacaa aaaagtgagt cagtaaaaga agaaggtgaa gtaatattaa aaaatgaaaa
     3721 aatattatct gaagaaaagt cgatagatga agaaggagtt gtggttaata ttgataatga
     3781 aatattaact aaagtagaag tagtaaatga tgataatgaa atacaagaaa aaataataga
     3841 agaagattgg ttaattagtg agaatacctt aaaattagat gataaagaag caattattaa
     3901 tgataaagac atagaattat gtaaaaaaga agttcaagtt gaaagtgaaa aaatagattt
     3961 aaataagttt gaagaacttg accaaaatga aaattataat ctagaaaaaa atgttattga
     4021 agaaaaagaa gtaagtgaat gtttgacaga agaagattta gagtacataa aagaaattaa
     4081 aataaaaaga ggaaaaagta taaaagctat aaacttgtat actaaagaag agtgggtttt
     4141 tgacactcat aaacagtgta gtaaaaaact caaagttcca ttagggtata tacgagaaaa
     4201 tttaaaatat ggatatatgg attactttgg agatgcaata aattatttaa gtgaagtatt
     4261 aaatatagat gaatactgca aaaatgaatg gagctatctc gataatagca aatctccatc
     4321 tgagatattt aatattctaa acaataaaat atttagcata aggctttcta atgaaaaaag
     4381 aaatgaaatt ttgacaaatg ataaaattga agcattaaaa atgaattata aatttgaatg
     4441 tattgatgaa gaatatgatg aatattttaa aaaatataag tctataatca aaagaggtgg
     4501 aaagaaaaaa gttgaattag taaataaaaa aggtgacgtt ttagaaatat ttaagtcttt
     4561 agaagaatgt gccatttatt tgcaaaagga aaagaatgaa gttatacaaa tgttaaaata
     4621 tggagataca aaagtaggaa ggaactttat aaggtatagt ttgagaagta tttaatttca
     4681 ttttaaattc ataagagttt catttctgat tcacacattt aatattattt taatgtaaaa
     4741 taataaaggt gaagtattgc acaattaaaa ttaaggaggg tattaatgtc tgaagaaaaa
     4801 aatccaaaag aaaatacatt agatgaatct aaaaattcag ataacgtaaa ttctaaaaaa
     4861 gatgatgtgt cagatgaaaa aaatactgat aacaaaatta aaaaaaggga agtaaagcta
     4921 aacaacaaaa cacttaaagc tattgtagca attgttgcag taggagctat atgtttaggt
     4981 ggaggctatg tttttggcaa agaagctgga agaaaattgc ctgctacttc aaaacactat
     5041 aatagcagtg aggtagtagc tactattggg gataaaaaaa taacaggtga aatgttaaga
     5101 aagagaatgg agccattatt ttatttaaat gcaaaaacta ctatgactga tgatgaaata
     5161 cgttcatatg aatcaaatat gattgaaact atgattacat ctgatatatt atcctctgaa
     5221 gcagcaaaag agaaaataag tataactaat gaccaactag atgctcagta taataattta
     5281 atgagtagta tagaatcagc aatgggaatg actaaagaag agtttttaaa acagtttgat
     5341 ttgactgaaa aatatataaa agatgatatg aaaaaagaac tggtagcatc aaaatactta
     5401 aatgaaaaat caaaagttac tgataaagaa gcagagaact attacaataa aaacaagaac
     5461 aattatttac aagttagagc ttcacatatt ttaataaaaa ctgttgatga taaaggtaaa
     5521 caagttagta atagtaaaaa agctgaactt aagaaagaag ctgaagaaat acttaaaaaa
     5581 gcccaagctg gggaagattt tgctactcta gctaaaaaat actctgaaga tagtagtgca
     5641 gaatcaggcg gagatttagg tttctttggt aaaggtcaga tggtggaatc ttttgaaaaa
     5701 gcagcatttg cattgaagaa gggagaagta tctaacaaac ttgtagaaag tgattatgga
     5761 tatcatataa ttaagaaaac tgatgaaaaa tatcaaccat ttgaagagat aaaatcagat
     5821 ttagtaagca gtttaacatc agaaaaacaa agcctactta tacaaaatct aaaagaaaaa
     5881 tataatgtta aaatcacaga taaatatcaa atgaaagcta aagaatagat aaagtcaatt
     5941 tataaaaaaa aagaaaaatt tactgtatgg ataaaagcta tttttgctct caatatagag
     6001 agtctaaaat agcttttatt atttttgaat aaaatctatt tacatatatg aagtgacaaa
     6061 gaaataacat gcaaaaaaat attaacaaga aatatcctta atttgaatta ttttagataa
     6121 aacatttata aaaatgaaaa aataaacaaa aaataattga agatttgagc tgttgtttaa
     6181 atatatatat atattaagat tttctactga aaatactgaa aaaataatat ttttcataat
     6241 tttaaaaata ataataaaaa aatgaaaata caggcgataa tctattgagt aaagatagaa
     6301 aagatgatat tataagtatg tgctaaaatg gttaaagcaa tcttaatatt aaatttaact
     6361 ataaaacaaa agggggcgtt tttttatgtc aagtacagaa agcgtatcta aaaaaggtgg
     6421 tcatcctaag agtttttggc ttatttgcat gacaatttta tgggaaagat ttagttatta
     6481 tggtttaaca gctttattgg tattattttt tacagcaagt gtagctcaag gtggattagg
     6541 tctttctact caagaagcaa catctatgtt tggtttattt acaggtctta tatatcttac
     6601 accattagtc ggtggttggc tagcagataa agttttaggt caacaaaaat gtatttctat
     6661 aggtgcactt ttaatagcaa taggagattt cgtactattt gcttcatcta catctattac
     6721 catggtttgg gtaggtctat caataattat tttaggaaat ggttttttta aatcaagttg
     6781 ttcaaatata gttggggata tatatcctaa aactgatgtg tcaagaaaag atgcagcata
     6841 cagtttattc tatatggcag taaatgtagg agcatttata gctccaataa tatgtggatt
     6901 actttctgat aatgtgtttg cagtaagagg agcaagtgga gatatagtat cttatggata
     6961 taagatggcg tttttaattt gtggtatagg catgatgtta ggtatgatta tatttacact
     7021 tcttgcacca aaattattaa atgaagtggg aaaatatcct gtgactaaag gcaataaagg
     7081 tgaaaaaatt gagtatggac cacttactaa gttggagaaa aatagaataa tagcaatggt
     7141 tattttattt ttatttgtgg tcttattctg gacagcatac tatcaaacac aaagttcttt
     7201 tatgatttat gtaagagaca atgtaaatag aactctattt ggatttgaaa tgccagtagc
     7261 atggcttaca tcactaaatg ctatattatg tgtggcttta tgtccagtat tagctaccct
     7321 atgggttaaa ttatctcata ccaaaagagg tgatttctct attccagtta aaatgggatt
     7381 aggaatgata ataatgggtg ttgggtttat agttatggta tttgctacat tagctaatgg
     7441 tccagatgga atggtaaagg ctagtatatt gtttatagta ttgacttata tatttacaac
     7501 agtaggtgaa ttattcttat ctcctatagg acttgcaatg ttcaataaat tagctccagc
     7561 taagtatgct acgttatcta tgggagcatg gtatctaaca agtttttttg caagtttatt
     7621 atcaggaaag attgctggtt ttacagctac acttggtttt ttacagatat ttggaggaat
     7681 agcaacagtt ttaataatat ttggtttaat attattggga ataagaaatg tattaacgag
     7741 actaatggct atggatttac taacaaaaga agaataattc atgacgaatt attgtaaata
     7801 gatgaattac tttaagtaaa ggaaattaca tttaaatata aaattaaatg taatttcctc
     7861 tttgattatg aaaaaaagct ttacacaaat agatattata attaaaatta taattgtgat
     7921 aatt
//
LOCUS       DAMKOJ010000129         7698 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000129 DAMKOJ010000000
VERSION     DAMKOJ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7698
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.138"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            73..1131
                     /locus_tag="PC592_003331"
     CDS             73..1131
                     /locus_tag="PC592_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HDF4057261.1"
                     /translation="MNCKWISKIDERKKCDREADSSGYCIFHKENKSDEEIQLMVDTL
                     NKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FKDKVLFNGCVFLENCDFNRTIFSKDYINDRIFEKVKFKGSDLIVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIVIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFRMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1235..2419
                     /locus_tag="PC592_003332"
     CDS             1235..2419
                     /locus_tag="PC592_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF4057262.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDNYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTSSGDLLGSVDIVSNNSIDNVPLKTKLKMKF
                     AN"
     gene            2626..3339
                     /gene="rpsB"
                     /locus_tag="PC592_003333"
     CDS             2626..3339
                     /gene="rpsB"
                     /locus_tag="PC592_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDF4057263.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3418..4329
                     /locus_tag="PC592_003334"
     CDS             3418..4329
                     /locus_tag="PC592_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDF4057264.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4413..5117
                     /locus_tag="PC592_003335"
     CDS             4413..5117
                     /locus_tag="PC592_003335"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDF4057265.1"
                     /translation="MDKPMYKRVLLKLSGEALAGEKGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5143..5700
                     /gene="frr"
                     /locus_tag="PC592_003336"
     CDS             5143..5700
                     /gene="frr"
                     /locus_tag="PC592_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDF4057266.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEDFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5703..5906
                     /locus_tag="PC592_003337"
     CDS             5703..5906
                     /locus_tag="PC592_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057267.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQDINYTIKSIEGKKDKDKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5935..6669
                     /locus_tag="PC592_003338"
     CDS             5935..6669
                     /locus_tag="PC592_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDF4057268.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6682..7461
                     /locus_tag="PC592_003339"
     CDS             6682..7461
                     /locus_tag="PC592_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDF4057269.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVNPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINEFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3185 a          781 c         1455 g         2277 t
ORIGIN      
        1 taagtatata aaataaaata atatccaaac taatacaaaa tagtaataat tgttttgtac
       61 tggaggatat ttatgaattg taaatggata tctaaaatag atgagagaaa aaaatgtgat
      121 agagaagcag attcttctgg atattgtatc tttcataaag aaaataaatc tgatgaagag
      181 atacagttga tggtagatac tcttaataaa gaagaaataa gtgaatttaa tggatttgtg
      241 tttgaaaatg aatttaatgc tgaagaaata ttaacttaca attataaaat actggatttt
      301 tctgaatcca tatttaaaca aaaagcaaat tttaaaaaat atatttttaa aaagaacatt
      361 atttttaatt atacagaatt taaagataaa gtgttattta atggttgtgt attcttagaa
      421 aactgtgatt ttaatagaac catatttagt aaagactata taaatgaccg tatatttgaa
      481 aaagtgaaat ttaaaggttc tgatttgata gttaataaag tagaaaattt tccacgaatg
      541 gatggaataa tttttagtat gtgtacaaag tttgtgttaa agaatgttga atatggaaaa
      601 agtgagtatg agcatggcaa gataaattat agaatagcta gaaatcaagc aacaaaaatt
      661 ggagaatatg agatgatagg attttactat tataaggaaa gaatttatag tagtaaaata
      721 atgaaacgtt ctaattatcc tactttcagt gactatttgg ttgaaaaatt ttttgaccaa
      781 atagcacgct acacgacagg ttatggagaa aagccatgga atatattatt agtgattata
      841 gtgataataa gtgtttttgc cttattatac ttatttgtag gtatagaaag ttcaaatagt
      901 acacttgtag ctttagatat aaacaatata ggtgattact cactaagtga gattttcaga
      961 atgtatatgg atttatggta ttttagtatg gctacattta gtacagtagg atatggagat
     1021 atggttgcta caagtttaat tgggaaagca ttagcaggca tagaagtatt ttttggagtt
     1081 acaataggag caatttgggc atctgtgatt attaaaagaa tgataaggta atatctgttt
     1141 aaatatagat aggtattaat tactagatat aaattggact aaatagggaa aatttaaata
     1201 taaatatact taataatcca agaaggtgaa aaatttgaaa aatgcactaa aaaaaattat
     1261 atcattagcc atgattctag tttttataat accaaattat tcatatgcag atgataaatc
     1321 tgtagacaaa tattcaaaaa catctatact tatagaccaa gaaacaggta gagttttata
     1381 tagtaaagaa cctgatatga aagtaccact agctagttta agtaagatga tgactttttt
     1441 acttgcaata gaagctattg aaaataaaga agtaaaagaa actgataagg taaagataga
     1501 caaatctatt gcatcagtaa aagggtcaag ttataaactt aaagatggtg aagaagtgcc
     1561 acttatagaa cttatgagag gtcttatgat tgtatcagga aatgatgcag caattgctat
     1621 agccaaacat atttgtaaaa caaaggaagc atttgtggat agaatgaata aaaaagcaaa
     1681 agaaatagga atgagcaata cacattttct aaatccaaat ggtcttccaa tatacgattt
     1741 aagtaatccc aaaaaaccag caaaagaaaa tatatctact gcaaaagata tagctattct
     1801 tggaaaatac atgtttgaca attatgaaaa acaagtaaca gctataactg atatggagac
     1861 atatacaaat tcagatagaa gttttgaaaa aagcaataca aatgcattat tgagaattat
     1921 accagaagta gatggtataa aaactggata tactggcaat gctggatatt gcttatcatt
     1981 ttctatggtt gtaaataaaa atgataaaaa tgagaaaaaa cgtagagtaa taggagttgt
     2041 attaggtact aatcataaaa ataaaagaac atctgcttca ttagctctac taaaatatgg
     2101 aaaagaaaat ttcaatatga aaaaagtaat tgataaagat agctttattg gtaagaaata
     2161 tataaaagga atgaaagagc tagaggttac attaaaagca aaagatgaac tttatacaat
     2221 attaaaagat gatgaaagta taaaatcaga agttaagatt aaaaatatag agtaccctgt
     2281 taaaaaaggc gatactatgg gtattataaa atattatact agttcaggtg acttacttgg
     2341 aagtgtagat atagtaagta ataatagtat agataatgta ccgttaaaaa cgaaattaaa
     2401 aatgaaattt gcaaattaaa ttcaaaaaat ggtataaaat acacaaaaaa atataaaaat
     2461 agaaaatatg gaaaaaatat tgttatttct tcacctctgt gatatactac tagaggtgaa
     2521 aaaataaaat aaatcacaca cagcattggg atccttaaaa ggtgcctatt acatggtttt
     2581 ttagggagaa gatcaagctg gaggtataaa accaggaggt aagatatgtc agtaatatca
     2641 atgaaacaat tattagaagc aggtgttcac ttcggtcatc aaacaagaag atggaatcct
     2701 aaaatggcta agtatatatt cacagagaga aatggaatat atataatcga cttacaaaaa
     2761 acagttaaaa aagttgaaga agcttacaaa ttcactaaag aagtagctga aacaggaaag
     2821 ccaatcttat tcgtaggaac taaaaaacaa gctcaagatg cgataaaaga tgaagctgaa
     2881 agatgtggaa tgtactttgt taatgaaaga tggttaggtg gaatgttaac aaaccacaaa
     2941 actataaaaa caagaataaa caaattaaga gaattagaaa aaatggaaga agaaggcgta
     3001 tttaatgttc ttcctaaaaa agaagttata aaattaagag ctgaaaaaga aaaactagaa
     3061 aaatacttag gtggaataaa agacatgcct gaattaccag gtgcaatgtt cgtagttgac
     3121 ccaagaaaag aaaacatagc aattcaagaa gctcatagat taggtatacc agtagttggt
     3181 atagttgata ctaactgtga cccagaacaa ttagactttg ctataccagg aaatgatgac
     3241 gctataagag ccgtaaaatt aataactggt gctatggcaa cagctgtaat tgaaggtaga
     3301 caaggtgctg aagaagaagt agctgaagac caagaataat aatttgacaa ttaaatggta
     3361 agggtcgccc ttaccattta taatatggaa tagaataagt aggaggaaac ttaaaaaatg
     3421 gctaatataa ctgctcaaat ggtaaaagag ttaagagaaa gtacaggcgc aggaatgatg
     3481 gactgcaaga aagctttaca agaagctgaa ggaaacatgg aaaaagcagt agatttatta
     3541 agagaaaaag gattatcaaa agctgctaaa aaagctggta gagttgctgc tgaaggtcta
     3601 gttgcaatag aaatgaatga tgataataca gttgcttcta tggtagaagt taactcagaa
     3661 acagatttcg ttgctaaaaa cgaagacttc aaagtgttcg ttaaagatgc tgcttgtatg
     3721 gcattagcta ctgataaaga agatatagct tctttattag gtgaaactca taaagaggga
     3781 ataactttac aagaagtttt aaataatagg gttgcaaaaa taggtgaaaa attagacttt
     3841 agaagatttg ctaaagttgt aactaatgga caggttgctg gatacattca cggtggcgga
     3901 aaaataggtg ttcttgttga aatggaaaca gaagctagag atgctaaagt tttagaatta
     3961 ggtaaagatg tagctatgca agttgctgct atgaatccta agtatgtttc aagagatgaa
     4021 gtagatgctg aatacatagc acatgaaaca gaagtattaa ctcaacaagc tttaaatgaa
     4081 ggaaaaccag ctaatatagt tgaaaaaatg gttaaaggaa gattagaaaa agaattaaaa
     4141 gaggtttgtt tattagagca aactttcgtt aaaaatccag atataactgt taaacaatta
     4201 gttgctgatg ttgctaaggc agtaggttct gatataaaag ttgttaaagt tgtgagattc
     4261 gaagttggtg aaggtataca aaagagagaa gaaaactttg cagaagaagt tgctaagcaa
     4321 cttaagtaat aaccaaagag agaacacgca ggtgttctct tttttaaaaa atagaaaaaa
     4381 tggatatgaa ggattgaaat aggaggtttc tgatggataa accaatgtac aaaagggtat
     4441 tgttaaaatt aagtggagaa gcattagcag gagaaaaagg ttttggtata aacaatgatg
     4501 tagttaatga tattgctatt gctataaaaa aaatacaaga aataggtgtt gaagtagctg
     4561 tagtagtagg tggaggaaac ttctggagag gtagaactag tgaaggaatg gatagaacta
     4621 ctgctgacta tataggaatg ttagctacag ttatgaatgc aatggcgcta caggatgcac
     4681 tagaaaatat agatgttgct acaagagttc aaactgctat agacatgaga caaattgcag
     4741 aaccatatat aagaagaaga gcagttagac acttagaaaa ggaaagagtt gttatatttg
     4801 gtgcaggaac aggaaaccct tactttacaa cagatacaac tgctgcttta cgtgctgctg
     4861 aaatggaagc agaagttatc ttgttagcta aaaatgttga tgcagtatat gacaaggatc
     4921 caaaagtaca tgcagatgct aagaaattta cagaattaag ttacatggaa gtaatacaga
     4981 aagaattaaa agtaatggat tctacagcta catctttatg tatggataat aaaattccaa
     5041 taaaggtatt tgagcttaca acagagaata taataagagc agtaaaaggc gaaaatatag
     5101 gaactactgt aaaataatga agaatgaagg aggagtaaaa ttatgaaact agaaatacat
     5161 aagcaattag aagagaaaat gaatgggaca attgatgctt taaagtttga atttggaact
     5221 ataagagcag gaagagccaa tgcacaaatg ctagacaaaa taagagttga ttattatgga
     5281 actccaactc caataaatca aattggtgct atatctgtac cagagccaag aatattaatg
     5341 atatctcctt gggataaatc tgctatgcat gaaatagaaa aagctatagc taactcagac
     5401 ttaggattaa atccatcaaa tgatggtgaa gttataagac tttctgtacc tgctttaaca
     5461 gaagaaagaa gaaaagaatt agctaaaaaa gctagtaaag ctgcagaaga ctttaaagtt
     5521 agaataagaa atgaaagaag agacgccaac gagaaaatta aaaagatgga aaaaggcgga
     5581 gaattaactg aagatgaatt aaaaaaagca caagatgaag ttcaaaaaat gactgataaa
     5641 tttataaaag aaatagatac attattatct aaaaaagaaa aggacataat ggaggtataa
     5701 tattgaaaaa atattataac cttttaggtc ttcatgtaga tgaggtaaaa caatattttg
     5761 atgagcaaga tataaattat accataaaat ctattgaagg taaaaaggat aaagataaac
     5821 ttgtagttcc tagagttata aaaatatctg agataggtga tagtgtagaa ctgataatca
     5881 catacttttc tgactcctta gtttaaggag tcagaacaat attggaggca aaatatgaat
     5941 aacaacatta tatatgatat agacttaaat aacataccta ctcatattgc tattataatg
     6001 gatggaaatg gaagatgggc aaaggctaga tttcttccaa gaactgcagg acataaggct
     6061 ggagtagaaa ctataagaga tatagtaaaa gaatgctcaa aattaggtgt taagcactta
     6121 acattatatg cattttcaac agaaaactgg aaaagaccga aacttgaagt tgacacactt
     6181 atgaacttat tatctacata cttaagaaat gaaatagctg aacttcacca aaacaatgta
     6241 aaagtaactg ctataggaga tataagtgct ttaccaaaaa cttgtataag agaattaaac
     6301 tcagctaagg aactgacaaa aaacaataca ggagttaact taaatttagc attaaactat
     6361 ggaagtagag cagatataaa aaatgctctt atagatatag taaaaaattg tgaaagtggt
     6421 aaaatagata taaacaatat tgatgaagat attataaaaa actatttaag cacaaagtct
     6481 ataccagatc cagacttggt aataagaaca agtggtgaac aaagattgag taacttttta
     6541 ctttgggagg ttgcttattc tgagttttac tttactgata tacactggcc tgattttaaa
     6601 aaagaagaac tacagaaggc tatatacgta tatcaaagaa gggatagaag atttggagga
     6661 cttaagtaag gagattattt tatgcttaca agaattattg cttcactagc tctggttcca
     6721 ttatttctat ttgttgtata tggagggatt cctctatata tagctgagac agcaatagtt
     6781 tatattgcat tacatgagtt ttataaggca tttaaaataa aagatgtaaa tccaatattc
     6841 attataggat atttattttc tatttattta gctgtaaaaa atatttttaa tttaccattg
     6901 gaatatactt atgcagtaat ttttatttta tttttagcaa gtataattta tatgttgatg
     6961 ggcaaaaaca atgttataga tgtttcgatt acgtttctag gagtttttta tataggagta
     7021 tttttagatt ttataattat aactataaat gaatttgaaa aaggcagtat atatgtatgg
     7081 cttatatttg tgatatcttt tatgacagat atatttgcat attttagtgg ttatttactt
     7141 ggaaaacata agttaattcc taaagttagt cctaaaaaga ctatagaagg agctattgga
     7201 gggataatag gaagtacact ttgttgtatt ttatttggat atttatttgg tattgatttg
     7261 cttcaattag cgataatagg aagtatagga agtgtaatag ctcaattagg ggatttattt
     7321 gcatcttcta taaagagata tgtagggata aaggattatg gaaagataat acctggtcat
     7381 gggggtatat tagatagatt tgatagtgtt atattagttg caccttttgt atatagtgcg
     7441 attaaatttt ttattagata aagattggtt ggatataaaa gagcaatcta taattgctag
     7501 taatgaaaat agctatgtaa cttttaaaag tagagatatt ctgcagttat tagttacatg
     7561 gctattttca ttgtttgata atttagaaaa tattaaggaa attttataaa attatagagt
     7621 actttataga aatatactat atttgtagta tgaatatttt atataaaaga actgttttca
     7681 aaaagtattt ttttgttt
//
LOCUS       DAMKOJ010000130         7659 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000130 DAMKOJ010000000
VERSION     DAMKOJ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7659
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.139"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     repeat_region   66..2996
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=198..226
                     /rpt_unit_seq="ctttacataccacatagttaatataaaac"
     gene            complement(3275..3427)
                     /locus_tag="PC592_003340"
     CDS             complement(3275..3427)
                     /locus_tag="PC592_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057270.1"
                     /translation="MDNFLQGILASLVASLIVYLTSKLFKKVKSHSGRSDFSFELEIK
                     FKKNKH"
     gene            3947..4189
                     /locus_tag="PC592_003341"
     CDS             3947..4189
                     /locus_tag="PC592_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDF4057271.1"
                     /translation="MRNRQGIIKNQTFFEDVKLIDITPNLLKIYVNKIYKKYSLNSAK
                     NSIGFLNPLLHEAYILREIQEDVSKFVITSSKKIHL"
     gene            4255..4800
                     /locus_tag="PC592_003342"
     CDS             4255..4800
                     /locus_tag="PC592_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF4057272.1"
                     /translation="MPIYLMLTLGLHFGEAVSLRWCDVELDEGIINIKQTMIYVREKV
                     TFKSPKTEKSKRILTTPIELINLLKEEKIRQNKLKLQDILKNELDLICLNKYFRPWKQ
                     QMFFRLFNRLLEKNNLRYIKLHELRHTNATLMLLSGTNIKTISERLCHADIKITMNRY
                     SLVLEDIDREASDNLSKILFK"
     gene            5345..6190
                     /locus_tag="PC592_003343"
     CDS             5345..6190
                     /locus_tag="PC592_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF4057273.1"
                     /translation="MNITKRMTLLLTLLIVILITGCSPKESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISLENLEDFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSTLYYAQACNYMNFDGFPDYPDATYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQDLNKSLYFNKDNEDPKSNLNTI
                     KKHLK"
     gene            complement(6414..6578)
                     /locus_tag="PC592_003344"
     CDS             complement(6414..6578)
                     /locus_tag="PC592_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057274.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(7110..7441)
                     /locus_tag="PC592_003345"
                     /pseudo
     CDS             complement(7110..7441)
                     /locus_tag="PC592_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
BASE COUNT         3059 a         1134 c          792 g         2674 t
ORIGIN      
        1 aaatttaagt ttgtaataaa aaaagttaca ataaatagaa acattcttgt actcattgta
       61 acttcttaaa ttcaccactt agttaatata aagcgtaatt ttggaaaaaa taattacaga
      121 ggtaatacaa cctttacata ccacatagtt aatataaaat gaggcgtttt tttctgttcc
      181 gactcctgtt cctgtatctt tacataccac atagttaata taaaacaagg ctatacagga
      241 tgataattta aaagaaaact tcactttaca taccacatag ttaatataaa acagttcagt
      301 tggaaatata attgtagaac aatactctac tttacatacc acatagttaa tataaaactc
      361 attgatgcta acttaagtat tccttgtttt tgtgacttta cataccacat agttaatata
      421 aaacaaataa cttagtatgt ctaaatacaa attttagacc tctttacata ccacatagtt
      481 aatataaaac ttaatgatga aggaaaagaa tatgtagtat atgaatatct ttacatacca
      541 catagttaat ataaaacaag ttctatatac aactgtgcaa gttctgaatt aatctttaca
      601 taccacatag ttaatataaa acttaaccct cttgataaaa caaggaggta ttagatgaaa
      661 ctttacatac cacatagtta atataaaacg ataccgaagg taatttactt gcaatatcta
      721 aataccttta cataccacat agttaatata aaacgcggta aaatgttaga taaaactgtt
      781 acatttacaa actttacata ccacatagtt aatataaaac taagtttgaa cacacttatt
      841 ttcgacccct caatacactt tacataccac atagttaata taaaactttt tgagtatgga
      901 gataaagtaa aaattatact tccctttaca taccacatag ttaatataaa acttagcgtt
      961 gataaagatt ctatagtagt gagaggtgct ttacatacca catagttaat ataaaactaa
     1021 aaattgggat ataattcatc aacaaattta acatacttta cataccacat agttaatata
     1081 aaacattatc cttcatgtgc ttagctcttt tatatttttt ctttacatac cacatagtta
     1141 atataaaact ctagctatcc agaaacttat aaacctgctc cagattcctt tacataccac
     1201 atagttaata taaaacggat atgttgaagg aacacatatg ttgcaacaaa ccactttaca
     1261 taccacatag ttaatataaa actagcagga gatgatagag gggtatatca ccaggtgatc
     1321 tttacatacc acatagttaa tataaaacgt ttttctttat tagataaaag ttctccgtcg
     1381 aatctcttta cataccacat agttaatata aaacaatcat tccttttgtt tcatctttaa
     1441 gttttacgac ctttacatac cacatagtta atataaaact tagtaagcat aataattgct
     1501 tgtgtgatga tttgtttctt tacataccac atagttaata taaaacaaaa agaaactact
     1561 ttgtatcttt atgttggaat agactttaca taccacatag ttaatataaa actacttcgt
     1621 cttttttgat ttgaacgtct tattttcttc tttacatacc acatagttaa tataaaacga
     1681 gattttcata tagccataga ctgttttagt ttttctttac ataccacata gttaatataa
     1741 aactgcttgt gctgtaggtg ttccttgtgc tgtcatatct ttacatacca catagttaat
     1801 ataaaacttt aaataatacc ttagtagaat tatcagagaa aataacttta cataccacat
     1861 agttaatata aaactcctaa accttctatc ttctaaactc tcattacttt tctttacata
     1921 ccacatagtt aatataaaac atgataataa tgtagtgaaa cgaatagcaa aagagttctt
     1981 tacataccac atagttaata taaaacgagg cagaaataat taaatccaca atagatttag
     2041 ctatacttta cataccacat agttaatata aaacaaatcc ctgcaactgt agttggttgg
     2101 ggttataatg actttacata ccacatagtt aatataaaac taatgaaggt agcgttagta
     2161 ccaggacata cactaacctt tacataccac atagttaata taaaaccagt agctaattta
     2221 cttaatctat aagcatcaac ctcctttaca taccacatag ttaatataaa actatttaaa
     2281 tctgatgaat atactgctct tatttgccgc tttacatacc acatagttaa tataaaactg
     2341 tttgaacatg actttgaaca tgtttgtctt tcttctttac ataccacata gttaatataa
     2401 aacactaatt taaaaaacca cccacttgta gataatgcag ctttacatac cacatagtta
     2461 atataaaacc aaagtatagg tcagcatata aacctaaagt ggaagacttt acataccaca
     2521 tagttaatat aaaacgagag taaagattgt gatatagcat acaaaaattg gtctttacat
     2581 accacatagt taatataaaa cttaattgat tgttgagtaa atcctaattc ttttatttct
     2641 ttacatacca catagttaat ataaaactag tttattgtgt gtaaattctg cttcaaaact
     2701 tatttcttta cataccacat agttaatata aaactccact ccaagaatta ggaatagcct
     2761 tgctttcact ctttacatac cacatagtta atataaaact ctatgaccta ttggtgctaa
     2821 tccaagacct tctccacttt acataccaca tagttaatat aaaacgctcc tcacctctta
     2881 atacgccaga actcaaccct ctttacatac cacatagtta atataaaact tctttaggaa
     2941 tcatcagtat ggatgaatat cagtctactt tacataccac atagttaata taaaacccca
     3001 aaataaactt agcatttcca acacttacac atatgcaaca ctctaaaatt tgcagtgagc
     3061 gagcagtggt gcaaatgata acacttatca tacatcttca acgccttata tttcaatgct
     3121 taagccctat tttattcaaa aaatcgaaca ctgcaaaatt tctatatctt tattatatca
     3181 taaaaatatt atttttgaat atctgcacca atttgtggta taataaaaac aagaagaact
     3241 acaatctatt tagacgtaga gtgaagttca aatactaatg tttattcttt ttgaacttga
     3301 tttctagttc aaaactaaag tcactcctgc cagagtggct ttttactttt ttaaataact
     3361 tactagttaa gtaaactatt aaactggcaa ctaaacttgc taatatacct tgtaaaaaat
     3421 tatccataca tattcacctc ccttctatac gttgggagga ttatcttttg tatgaactcc
     3481 actctataaa ttgtagatta catcttcttg ctgaaaagat tataacatat atttttacat
     3541 attttcccta ctacattact ttttcaaaaa ttcatctata tatttatata caactaccct
     3601 atcatcaaat agtatttata acttagattt gatataataa aaccctattt atttaatgta
     3661 tcaagaatac ttataaatga agtgtacata tgaatatcaa atcagctttt ataagaaaaa
     3721 aaggtgggaa atttcatgta tatgtggaat atgtggaaga agaaaccgac aaaaagaaac
     3781 aaaaaagtta tggaagttat taaaagaaaa aggatgctga aaaacattta attgaaataa
     3841 aatcaactat agacaacaat aagtttgttg ctccaagtga tgtaacactt gtagaaaggt
     3901 gctatagata catagaggaa aaaaagataa tatttctctg tatactttga gaaatagaca
     3961 aggtataatt aaaaatcaaa ccttttttga agatgtaaag ttaattgata ttactccaaa
     4021 tcttctaaaa atatatgtta ataaaattta taaaaaatat tctttaaatt ctgcaaaaaa
     4081 ttcgattggt ttcttaaatc ctttattaca tgaagcttac atacttagag aaatacaaga
     4141 agatgtttct aagtttgtaa taacttcaag caaaaaaata catctgtaac taacttttat
     4201 actaaagaaa aagcacagtt tctattagaa aaatgtcttg aaactaactt agctatccct
     4261 atttatttaa tgttaacgct tggattacat tttggagaag ctgtatcgct taggtggtgt
     4321 gatgttgaac ttgatgaagg aattataaat ataaaacaaa caatgattta tgttcgtgaa
     4381 aaagtaactt ttaagtcacc taaaacagag aaatctaaaa gaatattaac aacaccaatt
     4441 gaattaataa atttattaaa agaagaaaaa ataagacaaa ataaactaaa attacaagat
     4501 atactaaaaa atgaattaga tttaatatgc ttaaataaat attttcgtcc ttggaaacaa
     4561 caaatgttct ttagactttt taacagatta ttagaaaaaa acaatcttag atatataaaa
     4621 ttacatgagc ttagacatac aaatgcaact ttaatgttgc tttctggaac taatataaaa
     4681 actatttcag aaagattatg tcatgcagat ataaaaataa ctatgaatag atactctctt
     4741 gttttagaag atatagacag agaagcatct gataatttaa gtaaaatact atttaaataa
     4801 tgctaagttc tatgtcagta agatgtcagt taatcacata tttttttaat tgtcagttaa
     4861 atatcaatca aatatttatt actagatagt agcaaaaact agtatttaac tgctatctag
     4921 tagtattata taatagctaa acataacata cctattaata ttactgcttt tagcaatttt
     4981 tttaataaac atcaatatgt aaaaattatc aataaatttt tacatcctca attaatataa
     5041 aaaattacta aagaatatat tctttttaaa aataaaatat gagaacatta ttcaggtttc
     5101 ttagatgcat ctgaagatgc ataaagagta tgtataattg gactattatt gaagaagtta
     5161 aattagacaa atttaatagt agcaatttaa aataacaaga aaataaactt ataaactagt
     5221 tatctaattt gtttttttaa ttttattaaa tactgttctt tatttatact ttaaagaaga
     5281 tgacttattc aatatttgat gctagaatat aattaataaa aatttaatta taggtgattg
     5341 tattatgaat attactaaaa gaatgacttt actcttaaca ttattaattg taatattaat
     5401 aacaggatgt tccccaaaag aaagtgctag tgaagttgca aaaaaataca ttgataagat
     5461 gaattctggt gactatgaaa cagcatatag tttattaagt aaagatagca aaaaaaaaat
     5521 tagtctagaa aatcttgaag attttcaaaa tattttagtt agtacaaaaa gaataattag
     5581 ttataaaata ggtaaagaaa aaatcataaa aaaatataag catgatggaa aagagtataa
     5641 aaatgttgtt aaattagaag aaacttttaa tataaaaaac cttctttata aaaaagatga
     5701 ttctctaaaa gtaaatagat attttgtggt tgaaaataat aaatataagc tattattgta
     5761 tgaaagtttc aaaaaagaat ttggcattaa tagtatggac cttgctcaac ttaagcttaa
     5821 tgattttgga ctaaaatact ttaaagaagt tgacctcata ctaaaaaaag ctattgctat
     5881 taatcctact gattcaactc tttattatgc acaagcatgt aattatatga attttgatgg
     5941 atttcctgat tatccagatg caacatacaa tgctttagat tcaattaata agtctttaaa
     6001 gtatttagat aaaaatgatt ctgactacaa aaaaaatgca agtaatatat ataacttaaa
     6061 aggagttata cttatgtttc acaaaagatt tgatgaagca caacaagatt taaataaatc
     6121 cttatacttt aataaagata atgaagaccc aaaatctaat ctaaatacaa taaaaaaaca
     6181 tctaaaatag atatttaatt tttgaaccta taaaatattt ttttatatat aattcagtac
     6241 tgaatcataa tctctactaa actaattaca agtttaaatt ataaagactt atttctatat
     6301 aaatgttact gtataacaat aagtttttta tttaaatttt aaaatattgc ctaaaaatca
     6361 taaaaaagaa ggtataaaga gctaccctca agctcaatat accttataaa tatctaaact
     6421 tcatttttta ctaatttttc tatatctttg ataatatgtt ctttagattt ttttccagct
     6481 atggcatcaa aaattgcaac agcctttttc tctccaaact tttctgctac atcattaaag
     6541 tctaaaaatc taacactttc ttttggttta ccaaacatat aacacctctc atacattttt
     6601 atatatctat tataacttct atagatttat ttttcaccaa taaacgttag acaaattagt
     6661 ccctttattt ttttagacta tctttacctt caaaattcct aacaaaacca gtttattcta
     6721 ctctataaat aaaaatagaa tatttaattt gtagaaaact gataatagaa tacaacaagt
     6781 aaaactttgt ttaatctatc tgcaaaagtc atctgttaaa actgctatga attataaaga
     6841 gtattctagt tcataaaaat acaaatatgc aaatataatt accttaatat tcaatttatt
     6901 taaaataaaa aatatacaaa agatttaata ataacaatat acaattctca atacaatcta
     6961 tgatgtaaat aattcaagac tactatatca ttttaaaatt tatatatgcg attctaaaaa
     7021 cttaataaga aatgaactta gaaaataaaa cttaatttca aatacttaaa tagactatta
     7081 ttatcctaaa taaactactt ctatcaaaat tatatattaa attcttctaa aatttttatt
     7141 gcaaatcttg cgtttggata tgtaatagac ccaccaccaa ttacacctat ttttatagct
     7201 tctataattt catctttact tgctccagaa ttaacacaac cctcaatatg ataacaaata
     7261 tactcatcac atcgacttaa aattgaaata gctagcctca ttaattcctt atttttttac
     7321 ttatagcccc ttctgaataa gtcttatcat caaggcttcc aaatactcta aaaaactcat
     7381 ttgtttcgct taatttttta ttgtaaaatc ccctatattc tttcatttct ctagtattca
     7441 tcttctacct actatgtttt tcttataaga aaatcacact gtgcttatat tttcaacact
     7501 aaatacaaat tttcaattta tgttcattag cctaacttat attatttttt gaaatctcaa
     7561 caagttatca tataagtaag attttttcag aactaaaata gaaatcttag taatttcttt
     7621 attatctatt ctagttctga aatagattat ttttatcca
//
LOCUS       DAMKOJ010000131         7641 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000131 DAMKOJ010000000
VERSION     DAMKOJ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7641
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.140"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            86..2314
                     /locus_tag="PC592_003346"
     CDS             86..2314
                     /locus_tag="PC592_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDF4057275.1"
                     /translation="MIHLKKTNSLKEILNWNNIKNLKPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITNDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVINNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSVSALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAESKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIETLNKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIILLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRIIKPFNDKFGDSNLT
                     GH"
     gene            complement(2550..2849)
                     /locus_tag="PC592_003347"
     CDS             complement(2550..2849)
                     /locus_tag="PC592_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDF4057276.1"
                     /translation="MYKNINKNQLKEMMKNEKDILLLDVRTKDEFREHKIENAINISL
                     QELINNIDEIYEYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMN"
     gene            3057..6098
                     /locus_tag="PC592_003348"
     CDS             3057..6098
                     /locus_tag="PC592_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HDF4057277.1"
                     /translation="MFKRKLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNSESYTKTKALAKEKIQTLLSKYGVVNAQYALIDNGKIEISGNGGVYSKQD
                     NKNLTKDNMYSIASISKMFTTTAVMKLVDDGKVNLDTPVVNYIPEFKMADNRYKEITP
                     RMLLNHSSGLMGSSFKNTLLLGDNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGNSQFDEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSHLKENSGLYASSNMVKVDVNDNG
                     TLTVSSPYIENGPEDKYIYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRNGKGYYLVDEKYTSQSYMFGSVKATPGLSD
                     ETPGYIVNTKIIDENNSNAFIEIPGVIGRDLSDIKLYKENGTEYLSFATQTYVSEDSI
                     TNLPAEKSFTCELASNGYAKWYKIGDDIANKKIEVNLPQNSSFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINENSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVI
                     LVGNSLDYNQKELFKTMRFKSITQIGGNGNENSFKQIKEIA"
     gene            complement(6260..7534)
                     /locus_tag="PC592_003349"
     CDS             complement(6260..7534)
                     /locus_tag="PC592_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF4057278.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKVECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHESCVKCGKCIAACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
BASE COUNT         2822 a         1066 c         1089 g         2664 t
ORIGIN      
        1 ttaactttac tatttgtgta aaaagtaata taatttaaaa ttgattataa atctaacttt
       61 tttctttatc aaaatatttt aggaggtgat acatttgaaa aaaactaata gtttaaaaga
      121 aattttaaac tggaataata tcaagaattt aaaaccttca aagggtttaa aaaatatatt
      181 agaaattttt aaaagtgacc taaaagatat acgtggtaat tatgcagtac ttgtaatagt
      241 tttaggtctt gcttttttac catctctgta tgcttggttc aatataaagg catcttggga
      301 cccttatgga agcactgcta atatgcttgt agcagtaaca aatgaagata aaggaaatga
      361 aatagcagga caaaagatta atgtaggaga ccaattaatt gaacaactta aggataacaa
      421 aagtttaggt tggcagtttg tagatgaaaa aactgctctt gaaggtgtta agaagggtac
      481 ttactatgca tcacttaaga ttccaaaaaa ttttactaaa gatttgacat ctttaattac
      541 aaatgatgtt aaaaaaggcg aaattatcta tactgttaat gaaaaaataa atgcagttgc
      601 accaaagatt acagataaag gtgcttctac aatacaatta caggttaatc agactatagt
      661 aaaaacagtt agtgaaatcg ttcttggtat atcaaacgga gttggtgcag gaatcgaaca
      721 cagtcttcca aagttaacaa aggttgaaaa ttcccttatt gaccttcaaa agagatttga
      781 ccatataaat aagactgttg atttagcttc tgatgctact tcaaaattat ctgatacagt
      841 taaagatatt aaatctgatt tgcctacaat taaaaagact ttgaatgata caaaactgtt
      901 atcaagtgac ttaaagaaat tcttagagga tacaaatgat aatttagatg aactttctcc
      961 tcttattaag tctgacttaa atttaatggt tgacctttcg tcttctgctt cttctcttac
     1021 attaaattta attgatgcag ttaatagtgg cagtgaagat gtacctaagt tgatagataa
     1081 tttatcagaa aaactttcta atttacaatc tttaaacgat actttggtgg attttttaac
     1141 taaattaaat caacttacat caaataatag attggatgat gtaataaata atcttgaaga
     1201 ctctagcaat aaaatagatt catctatatc aacattaaat gatattaaaa acaaagttat
     1261 atctggacaa caaccatctg taagtgcttt gaataatgtt ttaagtctat caaatggtat
     1321 tggaagaatt aatttaaata ttttaaataa ttttgactca aaaatatcaa aacctataaa
     1381 tagtatattt gcaaacagta taaaagtagc aaatgatata attactgttt tagataaagc
     1441 agaatcaaaa cttccaaagg ttgaagaaat acttactaca tctctaaaac tttcaggaaa
     1501 tgcacaggaa agtatatcat taataagaga aagacttcct ttagcaaaag ggatgttgga
     1561 tgatttgatt gaaactttaa acaaaattag taatggtgaa gatatgaaaa aattagtcag
     1621 cttgcttgaa agtgatatat tgacaaaatc taatttctta aaagaacctg ttgaagtgaa
     1681 aacagaaaaa ttatatccaa ttgaaaatta tggttctgca atgacaccat tttatagtgt
     1741 cctttctaca tgggttggta tattacttat ttcagcatta ctatctacat ctgtacatgg
     1801 aaactataaa ccttatgaaa tttactttgg aagaggtctt acttttttaa gtatagctct
     1861 tgttcaaggt tttataatcg gaactggaga tatattatta ttaggagtaa cagcaaaaca
     1921 tccaatttta ttgataattt tgcttatgtt tactagtatg gtatttaact ttatagtgta
     1981 ttctttagtt tctgtatttg gaaatgtagg aaaagcaatt gcaatagtac tattagtcgt
     2041 tcagattggt tcttctggtg gtacattccc tatacaagtt acacctacat tcttccaaag
     2101 aataaaccct atcatgccat ttacttatgc aataggtgct acaagggaag cagttggtgg
     2161 tatatatgct ccaaatctaa ctaaagatat actagttcta ttgctattta tgattctgtc
     2221 tatttgttta aatgtccttc ttaaaggacc tataaataga attataaaac catttaatga
     2281 taaatttggc gatagtaact taactggtca ttaaaaaatt aattctgtat ttaaatatat
     2341 tttttaacaa tactttaagt tcatattaaa aggtagtagc tttttagcta ctaccttttt
     2401 tcaacttaaa aactaatatt tactacagaa tatgcctcaa aaaaagtata aaaattcgtt
     2461 ctttcctaaa tctatcttat aaatatctaa agatattcct acttaataag cagaattata
     2521 tatagtattt aatgcataac ttatattatt taattcatgt aatcaattat tcctgagttt
     2581 aaattatata aatgttcaaa accttcttca gctaacaaat tacatgcagt aacacttcta
     2641 tgaccacttc tgcaataaac cactactttc ttatctttat actcgtaaat ttcatctata
     2701 ttattgatta actcttgtaa tgatatattt atagcatttt ctattttatg ttccctaaat
     2761 tcatctttag ttcttacatc caataataaa atatcctttt catttttcat catttcttta
     2821 agttgattct tatttatatt cttgtacata tatctaaaat tcctccattt ttatttatat
     2881 attacctata ccctttattc tttatacagc aacaaatatt atttttatat ttttctcagt
     2941 tatataaaaa gctatactta taaaagcttt ttttattgat aataatctgt tgattaaaat
     3001 aattaagaat gttatgctaa ttataaatta ttaaaaaggg aaagaggtaa tgtaatatgt
     3061 ttaagcgaaa gctctctaaa ttattatcta gtacattagt attgagtatg ttatttactg
     3121 ctgctccaaa tattactttt gctgataata caaaagataa ttccgaaaaa tatcaaagtt
     3181 ctgatataga attacatgat tatagtaaaa actcggaatc ttacacgaaa actaaagctc
     3241 ttgctaaaga gaaaatccaa actttgctat caaagtatgg tgttgtaaat gctcaatatg
     3301 ccttgattga taatggtaaa attgagattt ctggtaatgg tggagtttac agcaaacaag
     3361 ataacaaaaa tttaactaag gataatatgt atagtatcgc atctatcagt aaaatgttta
     3421 ctacaacagc tgtcatgaag ttggttgatg atggaaaagt aaatttagat actcctgttg
     3481 taaattatat acctgaattt aaaatggctg ataatagata caaggaaatc acaccaagaa
     3541 tgttattaaa tcattcatca ggattgatgg gaagcagctt taaaaatacg ctcttattag
     3601 gagacaatga ttcttatggt catgataact tcttaaaaga attacaaaaa caaagattaa
     3661 aagcaaaacc aggagctttt tctgtttatt gtaatgatgg atttacttta gctgaaattt
     3721 tagtagaaag agtatctggt atgtcattta ctaattttct tgacaaatac ataaataatc
     3781 cacttaactt acaaaataca aaaactacag aaaatagttt tgatagttca aaactagcaa
     3841 aagcatatgt accttattgg gaggatgcag ttccacaaga taaccttaat gctatagggg
     3901 caggtggttt atattcaagt gcagaaaatc tatgtacatt tgcacaaaca tttatgaaaa
     3961 actcaaatgg tattctttct cctgcttcag taaaagctat ggaaaacaaa gaatatttaa
     4021 atggtctatg gcctgaagga gaagattcta tacttggata tggtttagga tgggattgtg
     4081 tcaatactta tccatttaat cagtacaatt taaaagctct tacaaaaggt ggagattctt
     4141 tactattcca cagtaatctt atagttcttc cagatgaaaa tatggcagtt gcagttcttt
     4201 cttctggtgg aaatagccaa tttgatgaaa taattggaca agaaatctta ttgtctgcct
     4261 taaaagaaaa gggaaaaatt aaagaaataa aacctgataa aacatttagt aagccacaac
     4321 aagttaaaat gccaagtcat ttaaaagaaa atagtgggct ttatgcttct tcaaatatgg
     4381 taaaagttga tgttaatgat aatggtactt taacggtatc ttctccttat atagaaaatg
     4441 gacctgaaga taaatacata tacataggtc aagatagatt tgtatctgaa aaaggtaata
     4501 gttgtttaaa atttgtaaaa gaaaaaaata atattacata tctaaatatg agctcttatg
     4561 atgatgtccc tggattaggt caaacagcaa gtttatacta tgtagctcaa aaggtagatg
     4621 ataacaatat atcaaatagt gtaaaagaag tatggaaaaa aagaaatggt aaaggttact
     4681 atctagtaga tgaaaaatat acttctcaaa gctatatgtt tggttctgtg aaggcaactc
     4741 ctggcctttc tgatgaaact ccaggttata tagttaatac taagataata gatgagaata
     4801 attcaaatgc ttttatagaa atacctggtg taataggtcg tgatttatcc gatattaaac
     4861 tttataaaga aaatggtaca gagtatttat cttttgccac acaaacatat gttagtgaag
     4921 attctataac taatttgcca gcagaaaaat cttttacttg cgaactagca tctaatggtt
     4981 atgcaaaatg gtataagatt ggtgatgata tagcaaataa aaaaatagaa gttaatcttc
     5041 ctcaaaattc atcttttgcc gtttatgatg ataaaggagt tcctgtaaac tattctttag
     5101 ttacaaagaa caatagagtt agattgccaa aaggaggcgt aattgttttc ttaggaagtc
     5161 caaatgctag atttgaagtt acatatcaag acgaagtaaa tgcaagtgca cttacaggaa
     5221 ctgatagata tgaaacttct attaagataa gtcaagcagg ttgggaaaat gctgaaaatg
     5281 cagttttaat aaacgactca gcaattgcag atgctttggc tgcaacacca tttgcataca
     5341 agaaaaatgc tcctatatta ttaactggaa gctctcaaat aaatgaaaaa actttggctg
     5401 aattaaagag attaaaagtt aaaaatgtat atgtagttgg tggagaggct tctataaatg
     5461 aaaattctct agatactata aaatcaaata atatctctgt ctctagaatt tcaggaagtg
     5521 atagatatca aacttctatg aacattgcta aagaattgaa taatattagt aatatatcaa
     5581 aaatttcagt agttaatggt gaaaaaggat tagctgatgc agtaagcatt ggagctgtat
     5641 cagcccaaaa tgacatgcct ataatactta ctaatgaaaa tagtaatata actgaaataa
     5701 ataacttatt taaaaacaaa aaaattgata aatcttatgt aatcggtgga gaatatacag
     5761 tttctaaaaa tatagaaagc aaacttcaaa atccacagag aatatcaggt agcactagaa
     5821 atgaaactaa tgcaaaagta ataaaagaat tttacaagga ttctaagata gataacttat
     5881 atgttgctaa aaatggaatg aataaacaag atgatttaat agatggatta tctgttggag
     5941 ttttggctgg aaaaactaaa tctcctgtaa tactagtagg aaactcacta gattataacc
     6001 aaaaagaact atttaaaact atgagattta aatctataac acaaattggt ggaaatggaa
     6061 atgaaaactc atttaaacaa ataaaagaaa tagcttaaca taactaaaaa aggctatatt
     6121 caagtaatat taattgaata tagtcttttt ttatttcaat tataagtttt atatgtgtaa
     6181 aaattaaatt tagatattaa ataataagtt tattaagatg tagataagcc taaaaacctt
     6241 gtctttttta agttagtttc tatttatcat tcatacttaa caatttatct aaatatactg
     6301 actttaactg tttactagct aaaatctttt tagctggttc aagctttaat atagctgata
     6361 gtatagctcc catagctcta tgactagcta aagcattatt atcaaaaatt aaattttgta
     6421 actgaccctt ttcaattgcc atgagaactg ctctatgtac tgaatttgct ggagttatta
     6481 ttttttcatc tctctttaat aacataatgc tatttttatg gcaatttcta acacaaactc
     6541 cacaacctag acatctatcc tcatcaattt ttatatattc tttaccatct tccttaacct
     6601 tgcttattgc atctattgga catgcagcta tacatttacc acattttaca caactttcgt
     6661 ggtttatatt tggtataaaa cttgttgtct gtactggatg aagatttcca aatcttttag
     6721 ctgctaccat tgcttcacag caacatccac agcaattaca tataaacgta accccttttc
     6781 taacattttc tccacattga actaagttat gctcatatgc ttgatgaagt agttctttac
     6841 attctacttt atccacacgt cttgcaaatt tattgtttat caaagaattt gctacattgt
     6901 caaacgtcat acatatatcc ataggagcat cacaagcttt tccaacatgt tgcattctat
     6961 gtctacagta acacatactt atacctatat gagttgattc gtcaattatg tgagtagctc
     7021 tttcataatc taaaatacta acctcattat cattagttaa aacttcctct tgaacatata
     7081 ctcttccaag cttagtttct gttgaataaa ataaatcttt gataaaatct tcttctacat
     7141 tcatatattg atagtaaagt tctgctaaaa gtttttggtc tatatcgtgt ctcgttctca
     7201 tcatggcaaa ctcaaaaaaa ccagccattg gaggaggcat tatatatttc ttccctttat
     7261 tatcttctat atctagtatc agagccttgc tagcaagttt atctaatact ctatatgctt
     7321 cactttcact tacactccaa attttagctg ctgtttttac tctaaaaggc tttattggaa
     7381 gctgagccac taacttcgcc tcttgttctg tatataatac atttagtatc ttgtataatg
     7441 tatctgaggg tggagcacct tgtggaaact tgtttattct ttcttctaaa cttttataca
     7501 tattcttcgc agttatatga gaaatagtaa tcaccttctt tttctttgtt ttccaataaa
     7561 atcaaatatt ctttcttatt atatatcctc ttactttata taataccaat tctttctaaa
     7621 tagttaaata cctctagtaa t
//
LOCUS       DAMKOJ010000132         7557 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000132 DAMKOJ010000000
VERSION     DAMKOJ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7557
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.141"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(614..802)
                     /locus_tag="PC592_003350"
     CDS             complement(614..802)
                     /locus_tag="PC592_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057279.1"
                     /translation="MTLQDRIKEERLKLGLNQVELSKKFNMTKQTVSNWESENRIQDT
                     LMLTKLADFLCISRFSLG"
     gene            990..1223
                     /locus_tag="PC592_003351"
     CDS             990..1223
                     /locus_tag="PC592_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057280.1"
                     /translation="MNTKKTKGIYKNGGLKVSRTAICSVCGELLVDGYGDEFTNTKII
                     DLHGREFVIIIYKNCLEELLRKCANGGISNDNN"
     gene            1210..1467
                     /locus_tag="PC592_003352"
     CDS             1210..1467
                     /locus_tag="PC592_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057281.1"
                     /translation="MIIIRSQDRLDLMRVNRVEIDSKYVYAVFGEESNVREIGRYKSE
                     ERAIEVLSRIQDAIIAGTKFDIIKKDGVRYYKEKVFEMPVE"
     gene            1460..1840
                     /locus_tag="PC592_003353"
     CDS             1460..1840
                     /locus_tag="PC592_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057282.1"
                     /translation="MNKEGSEMLKVEKYFSGSLGINIIEDDPTCRNYLALYCCLVGIE
                     RKGKKVIPRIDSMLSEFGVKSRCKRPHNNKLIRLINVKTGEVKEFKSIDSTACFLGLK
                     QPAVSHILKRKTPSRSGWRAEYIK"
     gene            2377..2571
                     /locus_tag="PC592_003354"
     CDS             2377..2571
                     /locus_tag="PC592_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057283.1"
                     /translation="MNILIYKYIVNEHRDEADELDRDYGEFKIFNGGKCFSGCGRNFY
                     TLAKFKKMIITCPHYEKNIK"
     gene            3557..4129
                     /locus_tag="PC592_003355"
     CDS             3557..4129
                     /locus_tag="PC592_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057284.1"
                     /translation="MNENLSKEIKILGTIEVEEMKFHDIEGGFGVGKKSMSVKDIDEI
                     HNGKLKDINKNINNNRKRFKDMINTLDLKVSDLKSLSLEMGYSNQSYANANNIYLLPE
                     RDYSKRLKILEGKQYEKIVDGYFSMRKELNNPLLSASKELQAIFMLDKKQEFLETKIE
                     SVNEKLENFMDDAPLFNIEFESIVKIVLWK"
     gene            4572..4943
                     /locus_tag="PC592_003356"
     CDS             4572..4943
                     /locus_tag="PC592_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057285.1"
                     /translation="MKKQIMALGLTGLIGLGGLGLLANKSFADTPNKLKGDTTVAQGL
                     NKNATAKDVTEQVDTTIGKGLDKNAIVKDVVENNGEKSDTTVAPGLDKNATVKDTAEK
                     GNTTIAPGLDKNTIVKDIVVK"
     gene            5082..5339
                     /locus_tag="PC592_003357"
     CDS             5082..5339
                     /locus_tag="PC592_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057286.1"
                     /translation="MVKCTKLIGGVITMKKNILGVLLPLLTMIIIFVLSFENIITNSL
                     GLSDMDIKGILISGVVLYIPVSFLVNGIICAKKQIKWKISK"
     gene            5662..5946
                     /locus_tag="PC592_003358"
     CDS             5662..5946
                     /locus_tag="PC592_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057287.1"
                     /translation="MTFEVEFYTFEGINMEAEMYVQVAMMASKVVKITGVDEVIKKLV
                     KKFLNNKVEEALGKQRSKKELKLIENNFNEYMERSYKNYIYMNTIVFRNQ"
     gene            complement(6223..6459)
                     /locus_tag="PC592_003359"
     CDS             complement(6223..6459)
                     /locus_tag="PC592_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057288.1"
                     /translation="MAPNFNVENIVLEDKEIVSTPQKYVLISRYYDNGKTIAFIEMNS
                     TKYKTEYIRNFDQYVDEFSTLEETEECLQECLSA"
     gene            6796..7023
                     /locus_tag="PC592_003360"
     CDS             6796..7023
                     /locus_tag="PC592_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057289.1"
                     /translation="MAMVSISFGEKIKIILKRKNMTIGELAEKTGQTRQNLSNKFSRD
                     NFSEKEIRKFAKILECEFDFYFIIKDTNEKV"
     gene            7010..7348
                     /locus_tag="PC592_003361"
     CDS             7010..7348
                     /locus_tag="PC592_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057290.1"
                     /translation="MKKYKIGGNFYMEVTLHTGEINFFKEHEVAKNYIGELYNFIEEY
                     KLSMETVSILTNIDIKKLNDFYIGKGTLHYDELVLINSVIIMPFIDVFKTAKHNYEMI
                     IKSSKKYEED"
BASE COUNT         3133 a          690 c         1213 g         2521 t
ORIGIN      
        1 taataaaaaa atataattaa aaaaacgatt aataatctat aaaaatggaa aaaacatcca
       61 atatcctaca aaaatagatt tttttattac aattacaagt ttttattgca tctatttagc
      121 aaaagtatta ttatgcaagt aagataatta tcaaagacaa ttctgaatag tctgatttaa
      181 aagatacaat taaaggatat aaataggaat aatttataaa tattacagaa gatttataac
      241 taaaattacg aacgtaagtt tgttatatgg ggtagttgtg tggatgaatc aaataaatta
      301 atattagaat tgaataatat tttctgtgaa ttagagagta ttaataaata taagtttaat
      361 gaatataaag aaattgttaa aaacttacac aacaaaaaag aagaggaata atttctcttc
      421 ttttaaataa aattattttt gattatcaat ctttgatttt tcttcctcta taaagacatg
      481 agcaattttt aacatcttat ctttagtttt atcatctaaa tcaagaaata tctttattaa
      541 ttcttttaca tcgtcataac tatctagttc atcaatgaaa ttttcataat tatttatttg
      601 ctcattatta gctttacccc aaagagaatc tactgataca caaaaagtca gctaatttgg
      661 taagcattaa agtatcttga attctatttt cgctctccca attacttaca gtttgcttag
      721 tcatgttaaa ttttttagac aattcaactt gatttaagcc aagtttaagc ctttcttctt
      781 ttattctatc ttgaagagtc ataatattgc tccttttatt gatgtttata taagtaacta
      841 taaactattt gttatatttt ttataaaaca tataataaaa taaatacttt ttcgaaaaaa
      901 atgtaaaatt tgtgttgata gtaaactaaa agtagactga tatataaata taaagttaac
      961 ataaagttga ctagaaaaga ggtgttaagg tgaatactaa aaagactaaa ggcatatata
     1021 aaaatggagg tttaaaagtg agtagaacag ctatatgtag tgtttgtggg gaacttctag
     1081 ttgacggtta tggtgatgaa tttacaaata caaagatcat agatttacat ggtagagaat
     1141 ttgtaattat tatatataag aattgtttag aagaattatt aagaaaatgt gctaatgggg
     1201 ggattagtaa tgataataat tagaagtcaa gatagattag atttaatgag agttaataga
     1261 gttgaaatag atagtaaata tgtatatgca gtgtttggag aggaatcaaa tgttagagaa
     1321 ataggtaggt ataaatcaga agaaagagct attgaggtat taagtaggat acaggatgct
     1381 atcattgcag gaactaagtt tgacattata aaaaaagatg gggttagata ttacaaagaa
     1441 aaagtgtttg aaatgccagt tgaataagga ggggtctgaa atgttaaagg ttgaaaaata
     1501 ttttagtggt tctttaggaa taaatattat agaggatgac cctacatgta ggaactattt
     1561 agcattatat tgttgtttag ttggaattga aagaaaaggt aaaaaagtaa taccgagaat
     1621 tgatagcatg ttatctgaat ttggtgtgaa aagtaggtgt aaaagacctc ataataataa
     1681 gctaataagg ttaataaatg ttaaaactgg agaagtaaaa gagtttaaat ctattgatag
     1741 tactgcttgt tttttaggat taaaacaacc agcagttagt cacatattaa aaagaaaaac
     1801 tccaagcaga agtggctgga gggctgaata tattaagtag gaataatgga agtttcaagg
     1861 actgaataca caattaagag agcaaaagag ttgtatggca atggcaagga tatgtttatt
     1921 gctatagata attctagaga agaatatgag gagattgtta aaaatgaata ttttaactag
     1981 tattacatta ataatgacta gttttataat aggtagaatt tatgaatata gattgaattt
     2041 aaaagagtgt gaaaattgta atagtaaagg ctacgagaat atatgaaatt tatgtagata
     2101 aatagtaaag gcaattttat gaatgaaact aaaaacttta tagaattact ttaatttata
     2161 taaaggagta attattaata tgattacaac agaatttata gttacttggt agacaactag
     2221 aaaacgggaa aaaggaaaga catatagtca tgtatttaca gatttagaga aagcaagagc
     2281 atttaagaaa gaggaggaaa atataaaaaa attataatgt gaagctttta agtagagcta
     2341 tagtcgaaat cgaaatagat taggcaggtg tttttaatga atattttgat atataaatat
     2401 atagttaatg aacatagaga tgaagcagac gagttagata gagactatgg agaatttaaa
     2461 atatttaatg gaggtaaatg ttttagtgga tgtggtagga atttctatac attagctaag
     2521 tttaaaaaaa tgataattac ttgcccacat tatgagaaaa atatcaaata aaacttttta
     2581 aaaatggaaa agtgaatatg agagtaattg agtaaataaa ggaaagtgat tatatgaaaa
     2641 gaagaagatg cagttggtgt gggaaattat tttatcttaa ggaaaaatct aaggaggttt
     2701 attgttataa ggaatgtaaa aagaaggcta acagggtaaa gagctttaat gactaaggaa
     2761 tataatttaa aacaaaataa ttagaaggta aaaaatattt aattaattat actttttacc
     2821 ttcttaaaat agaaaaactt aactattaag atatttgtga gggttatgta tccaaaataa
     2881 taatattatt gcaaatagag gactgaacca aaatgccagt aaagtataaa gactactatt
     2941 taaagcattt ttagtcgaaa ctctattaca agcgattaat agtattatag ataaaatatt
     3001 agcaataatt tctaatatat ttgaattaaa gtcttgaaaa aagactaaaa aagaaaaaat
     3061 ataagagata ctcatacata taaaaaaaca ataattcagt attttaaatt ttaatagttg
     3121 ttttttatta tcattgattg ccataagtac tcctaaaatt atagatagta tgataaatgt
     3181 atttgatgct tgcaaataag aaaagatagt cataaattta ttctcctaat attaactata
     3241 aattgtaaaa aaataattta aataactaac aattgaataa ccaataaaaa atgtaaataa
     3301 ataaaaaaga aactttttaa atccatttaa tttaaatctt ttttctatct tttgacaaat
     3361 gaaatttatc ggaataaaaa caaaagtcgc aattaaaaaa gttattaaat actttgacat
     3421 aggataatag tccataaata atcacctcat aaattagtat aaccatagat taatatgagt
     3481 tgttaataat agcaatcaat ttttcagaac tgtaaataaa ttgaaataaa ttatccaaaa
     3541 aaaagagcaa tagactatga atgaaaattt aagtaaagaa attaaaatac taggaactat
     3601 agaagttgaa gaaatgaaat tccatgacat tgaaggtgga tttggagtag gtaagaaatc
     3661 gatgtcagta aaagatatag atgagataca taatggaaaa ctgaaggata taaataaaaa
     3721 tataaataat aatagaaaaa gatttaaaga tatgataaat acattagatt taaaagtgag
     3781 tgatttaaaa tcactgagtt tagaaatggg ttactctaat caatcttatg caaatgcaaa
     3841 taatatttac ttattacctg agagagatta ttcaaaacga ctaaagatat tagaaggtaa
     3901 acaatacgag aaaatagttg atgggtattt ctctatgaga aaagaattaa ataatcctct
     3961 tttaagtgca tcaaaggagt tacaggctat atttatgtta gataagaaac aagaattctt
     4021 agaaactaaa atagaaagtg ttaatgagaa attagagaat tttatggatg atgcaccact
     4081 attcaatatt gagttcgaga gtattgtaaa aatagtattg tggaaatgaa aatttcccta
     4141 tcaaaactaa ataattggct agggttaagg gattacccta gtcactatga acagactagg
     4201 cagggcgtga ggacgctatt agttcaattc taactatgtt caaaatcatt gatacactat
     4261 attaagtatc tgaattgaga ctaaaattca tacagttttg tatcttaatt cagaatctga
     4321 aaattgagtg gggtttggca acctcactaa ccatgcagat actggtattt aatctaagtt
     4381 cgattcttag gacctgctac ataatatgaa tctccctctt tataaaatga ctaagttcgg
     4441 gtaagcttag tcttttattt tttaaacaag aaaatgagaa tttggattaa ttagcattgt
     4501 aaacaatcag taaacattaa tatgatatta tttgtttaga aaataaaaca aagaaaaagg
     4561 agagaataat tatgaaaaaa caaattatgg ctttaggatt aacaggatta attggcttag
     4621 gaggtcttgg attacttgca aataaatcat ttgcagatac tcctaataaa cttaaaggag
     4681 atacaacagt agctcaagga ttaaataaaa atgcaactgc taaagatgtt acagaacaag
     4741 tagatacaac aataggtaaa gggttagata aaaatgcaat tgttaaagat gttgtagaaa
     4801 ataatggaga aaaaagtgat acaacagtag ctccaggttt ggataaaaac gcaactgtta
     4861 aagatactgc agaaaaaggc aatacaacaa tagctccagg attagataaa aacacaattg
     4921 ttaaagatat tgtagtaaaa taatttagtt tttatagctg gcaaaagggt ggaaatttat
     4981 tctgcccttt tgttttatta ataaaaattt acatatatta aatatggata gcaaagactt
     5041 agattaattt ctagctcttt tatattttaa aggttgtgtt tatggtaaaa tgtactaaac
     5101 taattggtgg ggtgataact atgaagaaaa atattttagg agtattgcta ccattactaa
     5161 caatgattat aatatttgtt ctatcatttg aaaatataat aactaatagt ttaggattaa
     5221 gtgatatgga tataaaagga atccttattt caggtgtagt attgtatata ccagtttcat
     5281 ttttagttaa tggtataata tgtgctaaaa agcaaataaa gtggaaaatt agcaaataaa
     5341 gtggaaattt ccagttttaa tatcattttt aggctcagtt gttattatga tgtatctaag
     5401 ttttgatagc attgaaatgg cattgtattt atcatattat tttatatcat attatattgg
     5461 atattggata actagtgcaa tgaagaaata aaattaaggt gtaaatataa aaaatagaat
     5521 aagttgagag actatcttta taaatggtct ttttttatac aatgaatcaa aaatgaaata
     5581 tatttatgca ttatggagag aaatatggta aaagtattat ttggaattat tttgtagtta
     5641 tagaatagtt tttgaaggat attgaccttt gaagttgaat tttatacttt tgaggggatt
     5701 aatatggaag cagaaatgta tgtgcaggta gctatgatgg caagcaaagt tgtaaaaata
     5761 actggtgtgg acgaagtgat aaaaaaatta gttaaaaaat ttttaaataa taaagtagaa
     5821 gaagcgcttg gaaaacaaag gagtaaaaaa gaattaaaat taatagaaaa taactttaat
     5881 gaatatatgg aaagaagtta taaaaattat atatacatga atactatagt atttagaaat
     5941 caataaaaac aattgatgat ttatatatac cattaacagt ttcaaagcgt aatatttttg
     6001 atgcttcttg tgaagaagat gtaactgata ttttaatcaa tagttataaa agatgacttt
     6061 ttaccaaagt acaaaaagtt tttgttgata gaccaagcag gtatgggaaa atccgactat
     6121 agctaaatga ttatctaagt caaaacttct atttatctct agttgtttgt tatttacaag
     6181 tcttttcagt atataagtct taaaacacat ttatatcacc ccttaagcac taagacattc
     6241 ttgcaagcat tcctctgttt cctctaatgt agaaaattca tcaacatatt ggtcgaagtt
     6301 tctaatatat tcagtcttat atttagtgct attcatttct ataaaagcaa tagttttacc
     6361 attatcataa tatctgctta ttaagacata tttttgtggg gtagatacaa tttccttatc
     6421 ttctaggact atgttttcaa cattgaaatt aggtgccatg ctatagttac ctactcttat
     6481 gtattcataa tcatcactga aacggatttt atcacgtcta acagagtcat cttctttata
     6541 agttataagt tttatcagtt cttttaataa cttctatcgt gtatatgcag tcaaggtcac
     6601 atatacttct tgttgcataa gttttaccta cttcaaattt tatcatttta aatacatcca
     6661 ataattaatt tgttaagttt attgtacact ataaagtgtt gtttataaat ataaaaatga
     6721 aattaaataa ttttttttgt aaattaaata cagataaaaa aaactatata gtgtataatt
     6781 atatagaaaa gcgaggtggc tatggtgtca atttcatttg gagaaaagat aaaaataata
     6841 ttaaaaagaa aaaatatgac tataggtgag ctagcagaaa aaacagggca aacaagacaa
     6901 aatctttcaa ataaattttc aagagataat ttttcagaaa aagaaattag aaaatttgca
     6961 aaaatacttg agtgtgaatt tgatttttat tttattatta aagatacaaa tgaaaaagta
     7021 taaaatagga ggaaattttt atatggaagt aactttgcat acaggagaga ttaatttttt
     7081 taaagaacat gaggttgcaa agaattatat aggagaatta tacaatttta tagaggaata
     7141 taagttatca atggaaacag tatctatttt gactaatata gatataaaga agttaaatga
     7201 cttttatata ggaaagggaa ctctacacta tgatgaatta gtacttataa acagcgttat
     7261 tataatgcct tttatagatg tatttaaaac tgctaaacat aactatgaaa tgataattaa
     7321 aagcagtaaa aaatatgaag aagattaata gaaaaaaggt agattctata taagtagtag
     7381 ctacctttta ttgttgttga taaagctggt gataagttat ggaaaactca tataaaaatt
     7441 gtggataaaa tattttactg acaaaagtta aaaaaataaa tgctgtaaat attataaaat
     7501 gttgaaaaat agccatatat atataatata agtaacacta taggtaaatt actgtat
//
LOCUS       DAMKOJ010000133         7437 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000133 DAMKOJ010000000
VERSION     DAMKOJ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7437
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.142"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            80..901
                     /locus_tag="PC592_003362"
     CDS             80..901
                     /locus_tag="PC592_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF4057291.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKNLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGIPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            922..2118
                     /locus_tag="PC592_003363"
     CDS             922..2118
                     /locus_tag="PC592_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF4057292.1"
                     /translation="MFIEFFYLLRSRGVNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDTVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWVLKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFRRKYSKTVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            2284..5682
                     /locus_tag="PC592_003364"
     CDS             2284..5682
                     /locus_tag="PC592_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF4057293.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNTLLTYPEIEFIEKPFVLQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSNGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELKMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLRNNITEEVEF
                     IVGEGERILNVNIWPDFVDDFSVHLVNPSNNQTQTISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWRIIFEPINIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKVARRLSNQSY
                     PNNSSGFGFLNLSDVDLYTLSSINQDLETEDIGYRSINKSFMDEANNYIPIDGYNVQI
                     HNGLEKEKYISKNISRQSGILSGIDVVHTPEFEEELAGLGQSQNFLKISDSLGVLSID
                     NTDYNSIQQVLQLPSIIRTIPTTKMTLLGEINRGTFGGVVATEEIGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHRDFIYPDGTSKIVYLWDQTKEGNPPDGFYIGTEYTREDIN
                     RAIAANDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGVAEDSELIVIKLGKIEGFYNS
                     AMLFAASQYAYNKAFELGRPLVINVSLGTSSLAGLTNRVNSEKAFFTRGLCVTAGAGN
                     EGNTQTHTSGIISHVGGSVEVELELNEEEEELSLELWLSRPDKADVIIVSPTGEESKT
                     VGVSNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRKLLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINSSLWQSSSRG
                     PTIENRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5692..7365
                     /locus_tag="PC592_003365"
     CDS             5692..7365
                     /locus_tag="PC592_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF4057294.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPIDFDET
                     ILNNIIQVAWWEESAPMSSLIEITNNVDNGETITTAAGTEYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILAGNGRVNSKYRGITTESDLIVVKLKSYIGTYYAGRINYSV
                     SDFLAAITYVTNIARTENRPLIINLTIGVKSGAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYAPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWTLRLTSELI
                     IGGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVAPGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQNNI
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
BASE COUNT         2842 a          859 c         1425 g         2311 t
ORIGIN      
        1 ttacattatt gttttatatc aaaaatagta ataaagtata tatacattta gaaaatactg
       61 tttaaaagga gtagaattta tgataaaaaa agagatatct aattttagag gaagtagtga
      121 ttatgttgta tcaccagaat tgatggcatc agttaatgtt gctattgcac ttgaaaaacc
      181 acttttgatt aagggagaac ccggaacagg taaaactatg ctagcacaag caatttcaaa
      241 tgaattaaaa aaaaatttag taatttggaa tataaaatca actacaaaag cacaagaggg
      301 gctttatgta tatgatactg ttcaaagact ttatgatagc caatttggag gagaaggtgt
      361 agatgatatt agcaagtaca taaaatatgg taaattagga gaggctttta gttcaaatca
      421 acaagtaatt cttttaatag atgaaataga taaggcggat ttagaatttc caaatgactt
      481 gctttgggaa ttggataaaa tggaatttta cataaatgag acaaaagaaa ctgtaagagc
      541 gaaacaaaga ccaatagtta ttataacttc aaatgcggaa aaagaacttc cagatgcttt
      601 tttaagaaga tgtatatttc attatataga atttcctgat agagatatga tggaggaaat
      661 agtcaaagtg cattttgata aagtagaaga acacctattg gaacaagtaa tgactacttt
      721 ttattggatt agaagtttaa aggatataca aaaaaagccg agtacatcag aattaattga
      781 ctggatacaa gcattaacat tgagtggaat acctattgaa aaaatagaaa aagaagttcc
      841 ttttgcagga atactactta aaaataatga ggatattgaa tctatgcaaa gacacttata
      901 gttaatagga gctggataat tatgtttatt gaattttttt atttattgag gtcaagagga
      961 gtaaatgtat ctttaaatga atggatgact ttaattgaag cattggataa aggactgtgc
     1021 tattcaaact tttcaaattt ttactatctt tgtaggatga ttctaataaa aagtgaaagt
     1081 gattttgata agtttgacac agtattttta gagtacttta aaggtataga acatcaagag
     1141 gaaattccag aagagattat gaattggctt aaaaaaccag atatagattt agaagagttt
     1201 gaaaggttag aacaaaatcc aaatataaat cttgacaaat taagagccaa attagaggaa
     1261 cgaataaaag agcaagattc tcctcataat ggtggtaatt attggatagg aacaggggga
     1321 acttctgagt taggacattc aggaaaaggg caaactggta tacgtatagg tggaaattct
     1381 acttatggta gagctgttct tgaagttgca ggagaaagaa aatacagaga ttttagagat
     1441 gatgaagttt taaatatgcg tcaatttcaa gttgcactaa agagactgcg tcaattttct
     1501 actagaatag atgctccaaa gacagagctt gatttggata agactattga agagacttgt
     1561 aataatgcag gttatttaaa actgtttttt gagaaaccaa gaaaaaatac agtaaaactt
     1621 ttattactta tggattcagg tggttcaatg agagggtata gcactttatg caatacatta
     1681 tttcagtctg taagtaaatc aaatcatttt aaagatgtaa agatatacta ttttcataac
     1741 tgtatttatg atagattatt tacaacacct gaatgttggt taagtaaatc tattaatact
     1801 gaatgggtat taaaaaatat agataaaaac tataaagtta taattgttgg agatgcttct
     1861 atgtcacctt ctgagttact tcatattggt ggtaactatc gtggtccata taattacaca
     1921 cctggtatag agtggcttaa aaggtttagg agaaagtaca gtaaaactgt atggatgaat
     1981 ccagaactga gagatggatg ggattcaatt aattattggt atcaaactca aagaatgata
     2041 caaagtgaat ttaatatgtt tccactgact gtaaaaggtc ttgagaaagc actgaaaaat
     2101 ttaatggttt caagataaag taaatataaa tgatggtatg atttattcaa aattgtacca
     2161 tcattattta tttttttagt atctctatta taaattatat aattgaaact taaaaattat
     2221 atagtctgat acattttaga cttacataga acatatacat taataataat tttagaagtc
     2281 gaggtgatta taataaatta tgaattaatt gtaaaataca atggagatat attgagatta
     2341 gaagaagaac taggtgtatc agtagagata cttaattcat catatgcaat aataacatca
     2401 agtaatgaag aagatgtaaa tacactttta acttatccag aaattgaatt tatagaaaag
     2461 ccttttgtat tacaaactca ggatgtacaa agtttttcaa gtacaggaat aacagggttt
     2521 aaaaatagaa ctggtttaac tgggaaagga actataattg gtataattga ttctggaata
     2581 gattatactt tacctgtgtt tagagatagt aatggtaggt ctaagatatt atattattgg
     2641 gaccagtcta ttcagggaaa tccaccagaa ggttttagag aaggaacatt atacactaat
     2701 gaagatataa ataatgcaat agatggaagt atgtatatac ctatttcaac aactagttta
     2761 catgggacac atgttgcagg tatttgtgca actattgcaa gtgatgccag aataatagtg
     2821 gtgagagttg gaaatataca aaccgatatt ttttcaagaa gtacagagtt tatgagggca
     2881 attaaattta ttttagatag agcattggag ttaaaaatgc ctgttacatt aaatataagt
     2941 tatggaagca atgaaggttc acatagagga acgtctttat ttgaacaata tatagatgat
     3001 atgtgtttat tttggaaaaa taatatagtt gtagcggctg gaaataatgc agataaaggt
     3061 ggtcataaaa ggattagact tagaaataat attacagaag aagttgagtt tatagttgga
     3121 gaaggagagc gtatactaaa tgtaaatata tggccagatt ttgttgatga ttttagtgtg
     3181 catttagtaa acccatcaaa taatcaaaca caaacaatat ctctaacttc aggtgaaata
     3241 aggaatacct tgggtgaaac tagaataact ggttattttt atcctatagc accatattct
     3301 cttacaagaa gagttacttt gcaattaagt tcaaatacac aaataactcc aggattatgg
     3361 agaatcatat ttgaaccaat aaatatagta acaggtaatg taaatatata tttaccaact
     3421 tctgaaggac taaatagaaa tactagattt ttgattccta ctcaagagct tactgtaaca
     3481 gttcctggaa cagcaagtag agttataaca gtaggcagtt tcaattcaag aacagacata
     3541 gtatctatat tttctggaga aggagataca caattaggcg tctttaaacc tgacctatta
     3601 gctccaggtg aagatatagt atctttttta ccaggaggta caagtggggc attaactgga
     3661 actagtatgg caactcctca tgttacaggg gtttgctcat tgtttatgga atggggaatt
     3721 gtaaatggaa atgatttatt tttgtattca cagaaattga gggcattact tttaaaagtt
     3781 gcaagaagat taagcaatca atcttaccca aataattcat caggatttgg ttttttaaat
     3841 ttatcagatg tagatttgta cactctatct agcataaatc aagatttaga aacagaggat
     3901 attggatata gaagtattaa taagtcattt atggatgagg caaataatta tatacccata
     3961 gatggttata atgtacaaat acataatggg ttagagaagg aaaagtatat aagtaaaaat
     4021 ataagtagac agtcaggaat actatcagga atagatgtag tccatactcc tgaatttgaa
     4081 gaagaattag ctgggttagg tcagagtcaa aattttttaa aaataagtga ttcattaggt
     4141 gtactatcta tagataatac agactataat agcatacaac aagttttaca acttccttca
     4201 atcataagaa ctataccaac tacaaagatg acattgcttg gagaaattaa tagaggtact
     4261 tttggaggag tagttgcaac agaagaaata ggcgtaaatt tctttaaaaa taatcctaat
     4321 attaatataa caggaagagg tactctaata tcaattgcag atacaggaat agactatcta
     4381 caccgagatt ttatttatcc agatggtacc tcaaaaatag tatatctatg ggaccaaaca
     4441 aaagaaggaa atccaccaga tggtttttat attggtacag aatatacacg agaggatata
     4501 aatcgagcta ttgcagcaaa tgaccctagt ttatctcagg acgaagttgg tcaaggaact
     4561 atgttgagtg gtatatgtgc agggcttgga aatgtgaata gtgagtatgc aggggtagca
     4621 gaagattctg aattaatagt aataaaactt ggtaagatag aaggttttta taatagtgca
     4681 atgttatttg ctgcatctca atatgcatat aataaagctt ttgaactggg aagaccgtta
     4741 gttataaatg tatctttagg taccagtagt ttagctggtt taaccaatag ggttaatagt
     4801 gaaaaagcat tttttactag aggtttatgt gtaacagcag gagcagggaa tgagggcaat
     4861 acacaaacac atacatctgg aataatatca catgttggag gctctgttga agttgagtta
     4921 gagttaaatg aagaagagga agaattatca ttagaacttt ggttaagtag gccagataaa
     4981 gctgacgtaa taatagtatc tcctactggt gaagaaagta aaactgttgg agtttcaaat
     5041 tataataaag taacaggttt atttgactta gaagggactg aatattctat aacgtatata
     5101 tatccaacta ctttttctgg acagcaattt actaatgtta ctttaaagaa tgcaaaaaga
     5161 ggtgtatgga agattcgatt agtaggggtt tatattataa cagggagata taacttatac
     5221 cttccaaata gaaaactttt aaaaagtgga actagattta gagaggtaga ccctttttat
     5281 actataaatt atcctgctat tcaagatgat ttaataacta taggagctta caatactatt
     5341 aacagtagtt tatggcaaag ttcatcaaga ggaccaacta ttgaaaacag attaaaacca
     5401 gatatagtag cacctggtgt taatataata gctgcttatc ctgggaatac ctatgcaact
     5461 ataactggta cagcagcagc aagtgcacat gcagctggtg ctgcagcaat gtattttcaa
     5521 tatacttttg ttgatggtag atatccaaat caagcctatg ttcaaaaaat aaaaacgttt
     5581 atgcaagctg gagctagaaa ggattcaaat acagtatatc caaatacaaa ttctggatat
     5641 gggcttttgg atgttagagg aatgtttgat gttttaagat aggagggatt tatggaaaaa
     5701 tcttattgta taatttatca aggtgatata gagtctgcac tacaagaaaa tggaataaat
     5761 aggtatatgg ttttaaatag tcaacttgca gtaatatatg tacctataga ttttgatgaa
     5821 actattctaa ataatataat acaggttgct tggtgggaag aatctgcacc aatgagcagt
     5881 ttaattgaaa taaccaataa tgtagataat ggagaaacca ttacaacggc tgctggaact
     5941 gagtatatct atgaaaatcc atataatgat ataaccggaa gaggaatttt attagcagtt
     6001 atagattctg gtatagatta tttgcatcct gattttataa atgatgacgg aaccagtaaa
     6061 gttttatatt tatgggacca agaagcaaat acaaatccac ctccagaagg ttttattttt
     6121 ggaagtgaat ttacaagaag tgagttaaat atagccataa atagaaatga tggaagtttg
     6181 agtcaagata atataggtac tggaacttta gtttctggta tattagctgg aaatggaagg
     6241 gtaaattcga agtatagagg tattactaca gaatcagact taatagtagt taaattaaaa
     6301 tcttatatag gtacttatta tgctggaagg ataaattaca gtgtttcaga ttttttagca
     6361 gctataacgt atgttactaa tatagcaaga acagaaaata gaccactaat aataaatctg
     6421 actattggag ttaagtcagg agctgtagca actacttcaa tactagatac ttttaatata
     6481 ttgagtagtg ctggtgtagt agtagtgagt ggcgcaggaa atcaaggtaa tacagatatt
     6541 cactattctg gaagatttag tagtgtaggt gaagttcaag atgtgataat acaggatgga
     6601 gatgactatg cactggatat aacactaaat actaatggtc cagataaagt aggtgcacag
     6661 ataatatctc cttcaggcga agttagtcat gacataaggt atgctccaga cttttatata
     6721 tatagaggaa aatttaactt agaaaatact acttatgcaa tgagatttat ttatccatat
     6781 attacttctg gaaaagaaaa tttggaaata agattaagag atataaaacc tggagtatgg
     6841 actttaagat tgacttcaga acttataata ggtggagaat atgatatata cttgccaaat
     6901 aaaaatttga tagctccaga tacaaggttt ttagaccctg attcagtagc tacaataact
     6961 atgtatgctg ctagtgatga tgtaattaca gttggtacgt tcaataataa gactgacagc
     7021 atgtggatag gttcttcaaa aggtccaatc cgaggaagag gaattaagcc agatatagta
     7081 gctccaggtg tagatataat atctacatat aaaaatggaa cgtataatac aggaacagga
     7141 accggtgtga gcagttctat agtcacaggt gttttagctt tactaatgga atatttggaa
     7201 aaacagaata atataccaag attatcattg tttacacaag ttttaaagac atatttgata
     7261 ttgggagcta caaagcttga gatatataca tatccaaatg tatcacaagg atatgggatt
     7321 ttaaacttaa aaaatacaat tcaacaaata gcaaatactc tatagataat aatctgcata
     7381 aatttatagt taattaatag ttcagataac aaaaaattga attagagtaa atataaa
//
LOCUS       DAMKOJ010000134         7433 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000134 DAMKOJ010000000
VERSION     DAMKOJ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.143"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            61..1038
                     /locus_tag="PC592_003366"
     CDS             61..1038
                     /locus_tag="PC592_003366"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDF4057295.1"
                     /translation="MRDKIVEIMLNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNICYKLDTEFIGKNIEHLETIDSTNEHAKRIAVN
                     SLDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNMGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IAEKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNKELVKCLDINEEGNLLVQRSDGNIKEIISGEVSIRGEKGYV"
     gene            1031..1990
                     /locus_tag="PC592_003367"
     CDS             1031..1990
                     /locus_tag="PC592_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HDF4057296.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMIQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGNFKCRPDLKMGYRACEVANIDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKAIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKK"
     gene            2184..2774
                     /locus_tag="PC592_003368"
     CDS             2184..2774
                     /locus_tag="PC592_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF4057297.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGGAIGFIFGISSLLNAIINPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            2793..3563
                     /locus_tag="PC592_003369"
     CDS             2793..3563
                     /locus_tag="PC592_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HDF4057298.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIINMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            3700..4668
                     /gene="dusB"
                     /locus_tag="PC592_003370"
     CDS             3700..4668
                     /gene="dusB"
                     /locus_tag="PC592_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDF4057299.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEDEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            4777..5256
                     /gene="greA"
                     /locus_tag="PC592_003371"
     CDS             4777..5256
                     /gene="greA"
                     /locus_tag="PC592_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDF4057300.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            5271..6800
                     /gene="lysS"
                     /locus_tag="PC592_003372"
     CDS             5271..6800
                     /gene="lysS"
                     /locus_tag="PC592_003372"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDF4057301.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMEIKDNFESLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNAEDPRRTDRFEVFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            7109..7303
                     /locus_tag="PC592_003373"
     CDS             7109..7303
                     /locus_tag="PC592_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057302.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFENTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
BASE COUNT         2965 a          749 c         1504 g         2215 t
ORIGIN      
        1 tgtataatta tttattagaa gaaaataagt catgaaatca tgtcatatta gaggtgaaat
       61 atgcgagata aaatagtaga gattatgtta aataataaat ctgaatttat ttcaggagaa
      121 gaattatcaa aacaattagg ggtgtcacgt gcagctatat ggaaacatat gaaagcctta
      181 aaggaagagg gatataatat agaatctgta aataaaaaag ggtatcgatt agcggaaaat
      241 ccaactgatt tattaagccc acagaatatt tgctataaat tagatacaga gtttattgga
      301 aaaaatattg aacatcttga aactatagat tcaacaaatg aacatgctaa aaggatagct
      361 gtaaatagtt tagatggaac tgtaatttta agcgaacatc aagatatggg gaagggacga
      421 ttgggaagaa gatgggattc aaaacctcat gaaggaatct ggatgagtat tatattaaaa
      481 ccagatatgg aaccattcaa agctccattt ataactttaa tagcaggagc aagtgtaacg
      541 aaggctttaa ataacatggg agcaaataca ttaataaaat ggccaaatga tgttatttta
      601 aatggaaaaa aaatatgtgg tatattaaca gagttatctg ctgaaattga aagaacaaac
      661 tacgttgttc ttggaattgg aataaatgtt aaaataatgg attttgaaca agaaatagct
      721 gaaaaagcta catcattgta taaagaagga tacatgttat ccagagtaga tattgttagg
      781 aatgtattga ctgaatttga aaaattatat ttagattata ctgtaaataa ttccaaagaa
      841 aaaaccttaa aaatatgtag agattattct gcaattatag acaaaaatat atatgtatta
      901 aaaggagata ataaagaact agtgaaatgt ttagatataa atgaagaggg aaatttatta
      961 gttcaaagaa gtgatggaaa tataaaagaa attatttcag gtgaagtttc tataagagga
     1021 gaaaagggat atgtataata atattttgga tatagaaggt ttaaaggttg ggcaagttga
     1081 ggatagaaat ggtcttactg ggtgtacagt agtaatatgt gaagaaggag ctacttgtgg
     1141 tgttgatgta agaggttctg ctccagggac tagagaaacc gatttattag accctgtaaa
     1201 tatgattcaa aaagttcatg cagtagtttt ggctggaggt tctgcatatg gtcttgaatc
     1261 tacttgtggt gtaagtagat acttagaaga aaaaggaatt ggctttgatg taggtgtagg
     1321 taaagtacca atagttgtag gagcagttct atttgattta ggagtaggta attttaaatg
     1381 tagaccagat ttaaagatgg gttatagagc atgtgaagtt gcaaatattg acattttaaa
     1441 tcaaggaaat tatggagctg gttgtggagc gactgttgga aagataagag gtcaagaata
     1501 tgctatgaaa ggtggcatag gtagttattc tataaaatta gataatggtc tagtcgtatc
     1561 tgcattaatt gctgtaaatg cccttggaga tgtttatgaa aatggtaagg ttatagcggg
     1621 tgctttaaat gataaaaaga cagaaacaat tgatacatat aaattaatga aacaaggtga
     1681 aagtaaaggt ggatttagtg tagataatac tactattggg ataattgcaa caaatgctaa
     1741 gttaactaaa gctggatgta aaaagatatc tcaaatggga catgatggat atgctaaagc
     1801 tatttttcct atccatacac ctcatgatgg ggatacaata ttcacaatat caacaggaga
     1861 aatagaagca gatataacat tagtaggttc attggctgta gaggttgtgg aaaaaagcat
     1921 aataaatgca gtaaaaaaag cggatagtgt agaaaatata atggcatata aagatatagt
     1981 aaaaaaatga gaaatatgat gaaattagca tatttttctt gtcaaattgt tgacaatggc
     2041 aactcatctt gataaaatta ttcttgttag agcgggcatc ctacaatggt agcttgactc
     2101 ataattataa gaaaaaaacg aaaaaaattt aaaaaattaa gtagtccggc atcgtaatga
     2161 gctggaacgg aggtgtattt tttatgatga acacaagtgc atcagtaaga aaagtaaatg
     2221 taagaaagat gactataata ggagtactat cagctatttc tattatgcta tctatgactc
     2281 cattgggatt tattccagtt ggacctacaa aagcaactat aatgcacata ccagttatta
     2341 ttggagctat tatggaagga ccaatagttg ggggagcaat aggatttata tttgggatat
     2401 caagtctctt aaatgctata ataaacccaa cagtgacatc ttttgttttt ataaatccat
     2461 tagtttcaat attaccaaga gttatgatag gtgtattggc ttattatgta tatcagttaa
     2521 taattaaggc tacaaacaag gtatacatat caggtttaat tacaggggct ataggttctc
     2581 tgttaaatac agctggagtt ttaggaatga tatatgtctt atatgctgac aagtatcttc
     2641 atgcaatggg taaaagtggt tcagcaggaa aagtaataat ggctcttgcc gcagcaaatg
     2701 gagtgccaga agcaatagta ggggctttag tagtagctgc tgttgccact gtacttaaga
     2761 aaagcaaaaa atagaaagaa ggttaatgac atatgcttct agtatttgat gttggaaata
     2821 ctaatatggt tttaggtata tataaaggtg acaaattagt taattactgg agaattaaaa
     2881 cagatagaga aaaaacttct gatgaatatg gaatcttgat aagtaatcta tttgattatg
     2941 ataatgtgaa tataagtgat attgatgatg ttataatatc atctgtagtt ccaaatgtta
     3001 tgcattctct tgaaaacttt tgtataaagt actgtaaaaa acagccatta atagtaggtc
     3061 caggcataaa aacaggtcta aatataaaat atgataatcc aaaacaagtt ggggcagaca
     3121 gaatagttaa tgctgtagca ggtatagaaa agtatggagc accaagtata cttgttgatt
     3181 ttggaacagc aactacattt tgtgctatct ctgaaaaagg tgaatattta ggtggaacaa
     3241 tagcaccagg aataaaaata tctagtgagg ctttatttca aagtgcgtct aaactaccta
     3301 gagtagaatt agctaagcca ggtatgacta tttgtaagag tactgtatca gctatgcaat
     3361 ctggaataat ttatggatat gttggtttag ttgataaaat aataaatatg atgaagaaag
     3421 aattgaattg tgatgatgtt aaggttatag ctacaggtgg attagctaaa ctgattgctt
     3481 cagagacgaa aagtatagat tatgtagatg gttttttaac actagaagga ttgagaataa
     3541 tatatgaaaa aaaccaagaa taattaatat acagggaatt gggttatata tccaattccc
     3601 tttttatgat agatttctac atatgtgtgg tatattataa tgaggaaata agaatttaaa
     3661 gttaaattac aaaataaagg aaaaaatagg agaaaaacaa tgaaaatagg aaatttagaa
     3721 ttgaaaaata aagtttttct atcacctatg gcaggtgtaa cagaccttcc atttagatta
     3781 atttgtaaag aacagggatg tgggctttta tatacagaaa tgataaatgg taaggcactt
     3841 tgctatgatg atgaaaatac taaaaaaatg cttaagatag aagatgaaga acatcctgta
     3901 gcagttcaga tattcggttc agagccagag tttatgggaa gagcagcaga gataatgaat
     3961 gattattcaa atgagattct cgatataaat atgggatgtc cagctccaaa agtagttaaa
     4021 aatggagatg gttcagcact tatgaaaaat cctaagcttg cagaagaggt attgagggca
     4081 gtagtgaaga actcaaaaaa gccagtgact ttaaagatac gaaaaggctg ggatgacaat
     4141 agtgtaaatg ctgttgaaat agcaaagata gcagaagatt gtggaataag tgctctagca
     4201 atacatggaa gaactagaga acagttttat acaggtaaag cagattggga tataattgca
     4261 gagattaaga aaaatttgag tatacctgtt ataggaaatg gtgatgtatt tacaatagaa
     4321 gattcaataa atatgttaga caaaactggt tgtgatgcta taatgatagg taggggtgct
     4381 caaggtaacc cttggatatt taaaagaata aaccattata tgaatacagg cgagattttg
     4441 ccagagccaa ctcttaacga aaaaataagt actgccatta agcatttaaa acttgcagta
     4501 gaagaacatg gagagtatgt agctgtaagg gaaatgagaa aacacatcgc ttggtattta
     4561 aaaggactta gaaactctgc aaaattaagg gatgaaatta acaaaataga agactatcaa
     4621 gaagttgtgt cgaaattgga gtactatatg gaagactcct tgacataaaa ataatagtga
     4681 cttataatat agcgcataaa ttaaaaaaag attataaaat ttttaaaata taattaggaa
     4741 aattcctaag gaatttgtga aggagttgta tttataatgg aagaaaataa agagttttta
     4801 ttgacacaag agggatatga taaattagaa gaagaattag aaaacttaaa ggttgtaaag
     4861 agaaaagaag ttgcagagag aataaaagtt gctatatctt ttggtgattt atctgaaaat
     4921 gctgagtatg atgaagctaa aaaggaacaa gcacaagttg aagaaagaat tttaaaatta
     4981 gaaaatatgg ttagaaaagc tgttatcata gatgaaagca aaatagacct taatgttgtt
     5041 acaataggat caatagttaa agttaaggat ttagaatttg atgaagaggt tgaatatact
     5101 atagttggtt cgacagaagc agacccatat gatggtaaaa tatcaaacga atctcctgta
     5161 ggaaaagcac ttttaggtag agctgcgaaa gaagttgtgg aagtgcaagt tcctgatgga
     5221 gttgctaagt ttgaaatatt agaaataaga agataatttg gaggaaaaaa atgaaaaata
     5281 atcaacaaag caatgaagaa gcgcaaattc aagaagacct tagtgaagta cttcaagtaa
     5341 gaagagataa actaaaaaaa ttacaagagt caggtagaga tccttttaaa gaaagtagat
     5401 atgatagaac tcattattct atggagataa aagataattt tgaatctctt gaaggcaaaa
     5461 ctacaaaaat agcaggacgt ataatgagca agagaataca agggaaagct ggctttatag
     5521 atattcaaga ccaagaggga agaattcaat cttatgtaag actagatgct ataggagagg
     5581 aagaatatag tgtattttca acatatgata ttggagatat agttggaatt gaaggggaaa
     5641 tctttaaaac taaaaaaggt gaaatctctg taaaggctaa atccgtagta ttactatgta
     5701 aatctttaca agttctacca gaaaaatatc atggattaaa agaccaagaa ctaagatata
     5761 gacaaagata tgttgactta atagtaaatc cagaagtaaa aaatgctttt ttaattagaa
     5821 caaaagcatt aaaagcatta agagcatact tagatgatag aggattttta gaagttgaga
     5881 ctccaatatt aaatactata gcaggtggag caaacgctag accatttata actaatcata
     5941 atactttaca tataccaatg tatttaagaa tagcaaatga attgtattta aaaagactta
     6001 ttgttggtgg atttgataaa gtttatgaaa tgggaagaat gtttagaaat gaaggtatgg
     6061 atttaaaaca taatcctgaa tatactgcaa tagaattata tcaagcatat gcagactata
     6121 ctgatatgat ggaaataaca gaaaatgtta ttgcgcatat ggctgaagtt gctacaggaa
     6181 gtatgatagt taactatcaa ggaacagaaa taaactttac accaccttgg aaaagaatga
     6241 gtatggaaga ttgtgttaaa gaatattctg gtgtagattt ttctactata aatacagatg
     6301 aagaggcatt agaagttgct agagaaaaag gtatagagat aaaacctgga atgagaagag
     6361 gagaagtaat aaatgctttc tttgaagaat ttggagaaga taaattaatc caaccaacat
     6421 ttataactca tcatccagtt gaagtatctc cattatctaa gagaaatgct gaagacccaa
     6481 ggagaactga tagatttgag gtatttgcta ataagtggga gttagctaat gcattttctg
     6541 aacttaatga ccctattgac caaaaaggaa gatttataga ccaattgaga aaaagagaat
     6601 taggtgatga tgaagctttt gaaatggatg aagatttctt aaaagcatta gaggtaggtc
     6661 tacctcctac aggaggacta ggaataggta tagatagagt aatcatgtta ttaactaact
     6721 ctccatctat aagagatgta ttattattcc ctactatgaa acctattgat aacaatccaa
     6781 ataaagaaga agagaactaa gaaatattag cattctacta agttttaaat aaagtttagc
     6841 tattaaatta gcaataaata gctaaacttt atttaaaatg tcagtgtaga atgcttttta
     6901 tatgtttcaa agattctttt agatatttaa tttataaatt accaacaaac gttagaaatt
     6961 gatattagtt tttgttgatt gagactttat atttagaaaa tatgattgaa agtaatttat
     7021 tatgaaaata tttagaataa tttttgagaa ggtaaaaaga ataatttctg agaatactat
     7081 atataaaaaa ttattggggg aatgtctgat gtttcaagtg attaattttt tatgtttatt
     7141 ctgtgttgga tttttagttc ttgatgttat gatatatttt tgtaaggatg caatggatat
     7201 ttttgagaac acaactaatg ttaataaagt taagagtata aatgtttggg ctgatagagt
     7261 cagagctaat tcatattctt atgaaaataa aattgcaaaa taggtaaaat tatatatgca
     7321 tgtattgttt gtaatatcaa gggttatatc tattggtttt aattaaaatt attaagaaaa
     7381 acaaaaagtt ataacctttt taaaataaaa aacaaaaaaa gtattgacga aat
//
LOCUS       DAMKOJ010000135         7184 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000135 DAMKOJ010000000
VERSION     DAMKOJ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7184
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.144"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            144..791
                     /locus_tag="PC592_003374"
     CDS             144..791
                     /locus_tag="PC592_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF4057303.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEIGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESVCAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(933..1502)
                     /locus_tag="PC592_003375"
     CDS             complement(933..1502)
                     /locus_tag="PC592_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057304.1"
                     /translation="MKKFTICIIMFAISALVLAGCTNDNKIKNEVDNMFNAIKTQDSD
                     AVDKYFPKLGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKVNNTDMVSIL
                     KKNPPKLGAMMPNPTMKDIDSANKKEFNLTLELVKSGDNYVCEVNQESAMKLLNVITG
                     GGTDYLADYNKDYYKQLDEEQKNYENQNN"
     gene            complement(1507..2406)
                     /locus_tag="PC592_003376"
     CDS             complement(1507..2406)
                     /locus_tag="PC592_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF4057305.1"
                     /translation="MKLLSNINNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKRLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLYKIPFPVKIKKVYGDKYLKYLKYLVLIIFVIILPVAIVNVAGGGDPWFCKW
                     ICPSGTFLGGIPLILGNENLRESIGFLFSWKLSILLLILLISIMIYRPFCRYICPLGA
                     IYSFFNPISIYRFKIDKDKCTNCTACQAKCKLDIPVYKDVNSLDCIRCGECIKACPHN
                     AITTTFSKDKKENKFCKKKYRGM"
     gene            complement(2559..3146)
                     /locus_tag="PC592_003377"
     CDS             complement(2559..3146)
                     /locus_tag="PC592_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF4057306.1"
                     /translation="MKRFFTLVLGCIFVLGVVSGCNKKTETNLVETNKNNSEWFNNLV
                     TEDVDGNKVTKDVFSSKELTLINTWTTWCGPCIGEMPELEALSKEYENNNSNVAIKGL
                     IVEVDGTDMKTGLSDKEKELVKDIMKKSGATYQQLTVSEGLKKTDFKRTIEFPTTYFV
                     DKKGNFVGEKVTGANSKEEWKKIIDERLKMVKDSE"
     gene            3569..4894
                     /gene="cdeA"
                     /locus_tag="PC592_003378"
     CDS             3569..4894
                     /gene="cdeA"
                     /locus_tag="PC592_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HDF4057307.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQNEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATNKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGILYFLSSKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGVTTFLFNIVALKLAGESGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIVALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNLTGLWLTVPFAEVLTIFISILFIKKYKGRYKY"
     gene            complement(4989..5783)
                     /locus_tag="PC592_003379"
     CDS             complement(4989..5783)
                     /locus_tag="PC592_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057308.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIMGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYNIELSVLLKRDMIWTSISALIEPSTSSISLTYLNYF
                     VQICLNEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(5784..6659)
                     /locus_tag="PC592_003380"
     CDS             complement(5784..6659)
                     /locus_tag="PC592_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057309.1"
                     /translation="MSSSIKIENLYHSFKKQNVFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQVFEFSSS
                     FYKNYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKSIKPKKAFGNTVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(6663..7031)
                     /locus_tag="PC592_003381"
     CDS             complement(6663..7031)
                     /locus_tag="PC592_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF4057310.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFIKNLLQEA
                     KKLEINREELVNIIINFKED"
BASE COUNT         2459 a         1106 c          816 g         2803 t
ORIGIN      
        1 tatgttataa ctatattgta actattttta taatcttagg aaaatattaa ttgtaaaatt
       61 aatgttatac aataatatat cgtataattt taattaacat aatagttaca acattaaaat
      121 ttaaatatgg gagtgatttt agtatgataa gacaaacacc attagaaaaa cgatatgaca
      181 agctaggtcc tcatattgta acagcactca aaaaacgtta ttttgatgct tattactgta
      241 aaactagaaa tgaagcttta caacaaattt tagatttaat tcctcaaaat catgttgtat
      301 catggggagg ctctgaaacg cttaaggaaa ttggtgtaca aactgctgtt agagagaagg
      361 gatttaaagt tattgataga gatttagcaa aaactccaga agaaagaaca gaaattatgc
      421 gtcaagcact tttatgtgat acttttttga tgagtagcaa tgcaattagt gaagatggac
      481 aactatttaa tattgatgga aatggtaatc gtgtagctgc aatgatattt ggtccaaaaa
      541 atgttatagt tgtagctggt atgaataaaa ttgtaaaaaa tattgatgat gcaatacaaa
      601 gaactagaac aattgcatct ccggcagttg ttcagcgttt tcaagatgtc aatacacctt
      661 gctatattaa tggaagttgt atagactgca caagtcctga aagcgtttgt gcatatatgg
      721 ttactacaag aatcagtcgt ccagcaaaaa aaataaaagt aatattggtg ggggaaaatc
      781 ttggtttata aaatatacat acatataaat agctctataa ataataaaat catatgaaat
      841 aacttattcc taaaagtggt agaatgaaag ccactctgca agactttcat tttaccactt
      901 ttacattctt ttaaatttat gcttctatat tattaattat tttgattttc ataatttttt
      961 tgttcttcat caagttgttt gtagtaatct ttattgtagt cagctaaata atctgtgcca
     1021 cctccagtaa ttacatttaa caatttcatt gcagattctt gattaacttc acaaacataa
     1081 ttatcaccag atttaacaag ctctaatgta agattaaatt cttttttatt tgcagaatca
     1141 atatctttca tagttggatt tggcatcata gctcctagtt taggaggatt cttttttaaa
     1201 attgaaacca tatcagtatt gttaactttt aaatctacag tcactttatc cttattattc
     1261 tttatatctg aaatttccca tgtcatattt ttagaataca ttttaaatcc ctctttatct
     1321 tcatatataa gattacctaa tcctaatttt gggaaatact tatctacagc gtctgaatct
     1381 tgtgttttta ttgcattaaa catattatcc acttcatttt ttatcttatt atcattggta
     1441 catccagcta ataccaatgc cgatattgca aacattataa tacatatagt aaatttcttc
     1501 attaaattac atccccctat actttttttt acaaaattta ttttcttttt tatcttttga
     1561 aaaagttgta gtaattgcgt tgtgtggaca agcttttata cattcgccac atcttataca
     1621 atctaaacta tttacgtctt tatatactgg tatatcaagc ttacattttg cttgacatgc
     1681 tgtgcaattc gtacatttat ctttatcgat tttaaatcta tatattgaaa taggattaaa
     1741 aaaactataa attgctccta aagggcatat atatctacaa aatggtctat aaatcatgat
     1801 tgatatcaat aatatcaata gaagaatgct taacttccaa ctgaataaaa atcctattga
     1861 ttcccttaaa ttctcatttc ctaaaataag tggtattcct cccaaaaagg tccctgatgg
     1921 gcaaatccac ttacaaaacc aaggatctcc acctcctgct acatttacaa tagcaactgg
     1981 cagaataatt acaaatatta ttaagaccag gtactttaaa tattttaaat atttatcacc
     2041 ataaactttt tttatcttta ctggaaatgg tattttatat agtaaatctt gcacaagtcc
     2101 aaatgggcaa agccaaccac aaacaaatct accaaaaaag gctccaaatg ccattaaaaa
     2161 accaacaaca taaaatgaga atttatactc tctgcttgat aaaactgctt gtaatgaacc
     2221 tattggacat gctccaagcg cgcctggaca tgaataacag ttcaatccag gtacacacaa
     2281 tcgtttactt tctcctccat atatagttcc ttctaaaaat ccatttacat atccatttgt
     2341 caatgctgta aatgcaactt gagtaataag ccttatatta ttgtttatat tagataataa
     2401 cttcatacct tttctcctaa ccaataccaa tacactctag acaaatcata attgctttag
     2461 ttaatactgt atttgattct ccacgatatg tacctaatac aataaatata aaactaatta
     2521 caataataga aatgcctgtt ttgttatctt taataaagtt actcactatc ttttaccatt
     2581 tttagccttt catcaataat ttttttccat tcttccttgc tatttgcacc tgttaccttt
     2641 tcacccacaa agtttccttt tttgtccaca aaatatgttg ttggaaactc tatagttctc
     2701 ttaaaatcag tttttttaag accttcagat acagtcaatt gttggtaagt agcacctgac
     2761 tttttcataa tatctttgac taattctttt tctttatctg aaagaccagt tttcatatca
     2821 gttccatcaa cttctacaat caatcccttt atagctacat ttgaattatt attttcatat
     2881 tcttttgata aagcttcaag ttctggcatt tcacctatac atggcccaca ccaagtagtc
     2941 caagtattaa taagggtaag ttctttactt gagaatacat cttttgttac cttatttcca
     3001 tcaacatcct ctgtcaccaa attattaaac cactcactat tattcttgtt tgtttctacc
     3061 agattggttt ctgttttttt gttacaacca gaaaccacac ctaaaacaaa gatacaccct
     3121 aaaactaacg taaaaaacct tttcatacct cacactccta taatttatat agtatataaa
     3181 atcgtcgttt gaaataaaaa taacttatct tctataatta aagtcatttt atttaataaa
     3241 taagagtcaa ttaaatcaaa ttgtataaaa gatatacagt taaaatatat ttcttttcag
     3301 acaaaatctt atatctaaat aatagattgt aattcttaag attatataca tatatttcta
     3361 aagattttct taagaaaaat ttagatttca ctaatacaat atacgtactt ttaataatat
     3421 aagcttatta attagcatta tactaattca tttcactatg attttttgtt gattttaagc
     3481 tgtttaccat atgaataaag tttttcttga ctatatagtt actatatagc ttattatata
     3541 tagagagtaa caaaaggagg taaaatttat ggaaaattta tttacaagaa aattcactac
     3601 ttttgaattt ctaaaatttg tttctcctgc aattatatcc atgatattta tatctttgta
     3661 cacaataata gatggcatct ttgtatcgac attagttggt tcagatgctc ttgctagtat
     3721 aaatattgta ctacctataa ttaatcttgt ttgtggattt ggaataatga tggcaactgg
     3781 tggaggtgct atcgtttcta tacgtatggg tgaaaataga cagaatgaag ccaattctac
     3841 attttctttt atagttttgt tttcattgat tgttgggatt ttattcacag taatctcata
     3901 tttctttatc aaagaaatat ctattttgct tggagcaaca aataagttac taccatattg
     3961 tataacttat ggaaaagtta tgattttatg tacaccattt tatattttaa aatttatatt
     4021 tgaatacttt gcaagaactg atggaaattc taaatttagt ttatttctat cagtcattgg
     4081 tggtgtaaca aatataatat tagattatgt atttattaaa tattttggaa tgggtctttt
     4141 aggagctgca gttgcaactg ctataggtat tattttaact tgtgttttag gcattcttta
     4201 cttcttatcg agtaaatcta cactaaaatt aagaaaacca aaaaccgatt ttagacttat
     4261 aagagatact atgataaacg gttcttctga gatggtcaca gaactgtcta caggagttac
     4321 aacattctta tttaacatag tagccttaaa attagcagga gaaagtgggc ttgctgctct
     4381 taccatagta ttgtatgctc attttttaat gacatcagtc tatctaggat ttgctgctgg
     4441 agtgtctcca ttaataagct ataattttgg tgctgaaaat agtgataaat taaaagagac
     4501 atttaaacat tctctaaaat ttatatttgt ttcttccctt ttagtgttta ttgttgcttt
     4561 agtatttgca ccatttattg ttagggtctt tgtaaatcca gataacacag tatttaagct
     4621 agccttgcaa ggattaaaaa tatttgcatt tgctttttta tttgttggta taaatatatt
     4681 tgcatcaggc ttttttacag catttcacaa tggaaaaatt tcagctatta tatcttttag
     4741 tcgtgccttt gtttttataa tcataggaat tataattctt cctcctatgt tgaacctgac
     4801 tggattatgg cttacagttc catttgctga agtcctaact atatttatat ctattctatt
     4861 tataaaaaaa tataaaggta gatataagta ctaaaaatta atatttaaaa tcaacattta
     4921 ttaaaactaa tgaacctgct ttaaaataca aatttataaa tttgattttt aagcaggttt
     4981 tattttagtt ataataagtc atttgcatac tctttaattg gtgcttttct aagtaataaa
     5041 attataaata ttatgcaaat aactataatt cctacttttg ttccaaataa aataaacgga
     5101 ttctgaaatg aataaataat tttttctaaa tacaatagca ttttatgcat atttttagtt
     5161 gcaaaattaa ctatataaat taccattaat atcggtaatc ctatcaatat agtaatacta
     5221 gtaacttttc taactctata tgtaaaagct ccaagtaata ctcctataaa gcctatacat
     5281 atttcattta aacatatttg tacaaaataa tttaaataag ttagtgatat acttgatgtt
     5341 gaaggctcta tcagtgctga tatagatgtc caaatcatat ctctctttag taaaactgac
     5401 agttctatat tgtaacctgt tataatttct ataaataact tcgataaaaa aatcaaaact
     5461 atacctaaaa tagaaatcac aaagcttaaa ataattaaat ctatgacaat agcttttata
     5521 caactttttc tatctgctct tatacttaaa gctcctgaaa agtctttatt tgctatattt
     5581 actccataca caaatagtag tatagttata tatgttaaaa taggattcac aatcgtggat
     5641 aaattagttt tagatgcttc tccaaaaatc ttgaggataa acactggtaa aatattcata
     5701 acaattccca taatcataaa tataattata tacaatttag tatttttatt aaaaaatttt
     5761 atatatggct ttaattcatt caattacaat tcctccttct tagtcatgtt aacaaacata
     5821 tcttgtagcc ctatgtatcc tacatcaata tttgaatttt taagtatttt ttcatcattt
     5881 tcactaaaat caccatagta aaaataagca actgtatttc caaatgcctt tttgggcttt
     5941 atacttttta tacattctaa tttttctaac tcttctttat ttccagtaat ataatgagct
     6001 ttttgtttta tgacatcaat ttcttcatct ataataattt ttccctcatt caatattatt
     6061 acatgctcca gtaaatcatc tatttcatca atcaaatgag ttgatattat tattgtcctt
     6121 ggatttttta tataactatc taaaattatg ttataaaact cttgtctatt tactgcatcc
     6181 aaaccaattg ttggctcatc aaatatagtg atagctgaat tagaacaaat acctattata
     6241 tttgaaagta tggttttcat acctcttgac agttgtttat actttttttt agtatttaag
     6301 tcaaaatatt tgcataattc ttcttctaag cctttatcat aatttttata aaaactagaa
     6361 gaaaattcaa atacctgacc tactttaaaa tctggactat aaaattcttt ttccctgaca
     6421 atacaaactt cttccaaaac ttttatatct tcttttgggt tctttcctaa tatttctatc
     6481 tcaccttcat tttgaattaa ctgatttacc attatattta ataatgtggt ttttccagct
     6541 ccattcttac ctaataaacc atatatctta tttttttcaa aatttagaga catattatta
     6601 aaaacatttt gtttcttaaa actgtgatat aaattttcta tcttaataga actactcata
     6661 tattaatcct ccttgaaatt aattataata ttaactaatt cttctctatt tatttctaat
     6721 tttttagctt cttgaagtag attttttata aaattatgtt taaaattttc ttttctggct
     6781 tcttttataa tagtttttgc cccatctgat acaaacatcc ctattcccct cttcttatat
     6841 aaaatattct tatcaaccaa tatatttata ccttttaata ctgtagctgg attaatttta
     6901 taaagctttg aaagctctgt tgttgatgga acctgttctt cttcttttat tccatttgat
     6961 agtatctcat cttcaattgc tcgtgctatc tgaatgaata taggttcttc attgtttaat
     7021 actaatttca taggcttctc ctttctaagt tagttaatta ctcaactaac taactgtaac
     7081 actatcttat agtataatat tacatctgtc aatacgaaat aaaaaaatat atgcaaactt
     7141 ttatcaaaaa tacgttttta tagatactaa aaaatattat attt
//
LOCUS       DAMKOJ010000136         6889 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000136 DAMKOJ010000000
VERSION     DAMKOJ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6889
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.145"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            44..682
                     /gene="recX"
                     /locus_tag="PC592_003382"
     CDS             44..682
                     /gene="recX"
                     /locus_tag="PC592_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDF4057311.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEDELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENTIDKVIDFLKS
                     YNLINDSILAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTIDEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            835..2838
                     /locus_tag="PC592_003383"
     CDS             835..2838
                     /locus_tag="PC592_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HDF4057312.1"
                     /translation="MKSQKRFKILDIDIYLQPFESDIKKRMKHYEYMKSKILKNCKDF
                     SSFANAHLYYGFHKTNDGWVYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTTNGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTSFIWTDN
                     DFDLKNIISPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSVNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLSMGVPDFWIKTISNLSDENWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNPVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYIKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDI
                     VEFGGNTKKENLRDYDVYFSSTPPSSKIPIASRTAIVLLDNGI"
     gene            3012..3653
                     /locus_tag="PC592_003384"
     CDS             3012..3653
                     /locus_tag="PC592_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4057313.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYDVKNDEGKTALEKLQYRLLHAYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMQVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMVERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            3746..4429
                     /locus_tag="PC592_003385"
     CDS             3746..4429
                     /locus_tag="PC592_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057314.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPILDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRVGYQKDFDVTVPLLSQEQRDWLVKALITAYPDGHA
                     WIDQLANQH"
     gene            complement(4606..4917)
                     /locus_tag="PC592_003386"
     CDS             complement(4606..4917)
                     /locus_tag="PC592_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDF4057315.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKSLKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(4995..5813)
                     /locus_tag="PC592_003387"
     CDS             complement(4995..5813)
                     /locus_tag="PC592_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4057316.1"
                     /translation="MLSVTRYSIKNIRLKPWVKFIWFLETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKFENQDYTASNMHFNGIRDKHGFIVQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLNPTKAIEKVVLCLEEVLLSILEEDLISNKSV
                     ELLNSFIYVNRYSNIKAFCDDTNINIKTLERTCLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            complement(5913..6437)
                     /locus_tag="PC592_003388"
     CDS             complement(5913..6437)
                     /locus_tag="PC592_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF4057317.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIV
                     WANGKNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFVVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            complement(6460..6849)
                     /locus_tag="PC592_003389"
                     /pseudo
     CDS             complement(6460..6849)
                     /locus_tag="PC592_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
BASE COUNT         2570 a          956 c          978 g         2385 t
ORIGIN      
        1 agttgctttt gttaatataa ttacatataa aaaaggagga tttatgggta taattacaaa
       61 aatagaacaa caaaaaagaa atgatgatag agttaatatt tatgtggatg ataaattttt
      121 tattgctata tttaaagaac ttgtttatac atttaattta aaaaaaggaa atgaaataaa
      181 tgaagatgaa ttaaaaccta ttttagatga tgaaatgtat ataaaagcta aaaataaagc
      241 actaaatatt ttatctcatg ctgaccagtc tgaaaaaaaa ttaaaagaaa aactgtcatc
      301 agaatttgat gaaaatacaa ttgataaggt catagatttt cttaaaagtt ataatctcat
      361 aaatgacagt atattagctc aaaaaatagt taacacaaat gttaatctaa ataaatgcgg
      421 aaaaaacaga attaagcaga atttatataa taaaggtatc aatagaagta caattgatga
      481 agcagtatct gaattagata aggacactga atttgaaaat gctatgtatc tagcaaaaaa
      541 aaggtatgaa agagtgaaga aggaagataa aaagaaaata tatcaaaaaa tttctcaaca
      601 tctttcctat aaaggctttg attatgatat tattaaaaga gttttaaaca aacttttaaa
      661 ttttgatgaa tacgatatat aagtatagat actagggagg taaattatga aattaatcat
      721 tggtggctta agctttttat tgggattata taatatatat caattatata gagaagatag
      781 tatgagataa atattatttt ttagatgtaa tatttactat ggaggagaaa tacaatgaaa
      841 agtcaaaaaa gatttaaaat tttagatatt gacatatacc tacaaccatt tgaatctgat
      901 ataaaaaagc gaatgaaaca ttatgaatat atgaaatcaa aaatattgaa aaactgtaaa
      961 gattttagtt cttttgcaaa tgctcatctt tactatggat ttcataagac aaatgatgga
     1021 tgggtctata gggaatgggc tccaaatgca gatagtttat cactaattgg tgactttaat
     1081 aattggaata gaaaatctca tcccctaaga aaaattggtt ctggtaattg ggaaatattt
     1141 attcctggtc aaaatagctt acctcacaaa tcagaggtaa aggtacaagt tactacaaat
     1201 ggaaaaacat ttgaccgtat accattatat ataaaaagag taattcaaaa agattttggt
     1261 ggatttaatg gacaaatatg gcaaccaaaa acttcattta tatggactga caatgatttt
     1321 gacttaaaaa acataatttc tccactaata tatgaatgtc atataggtat gtctactgaa
     1381 agcgaatcta ttggaactta taatgaattt actgaaaaaa tacttcctaa gataaaaaaa
     1441 gctggataca ataccattca gcttatggct attatggaac atccatatta tgcatctttt
     1501 ggataccaag tttcaaactt ttatgcaatc tcatctagat ttggtactcc tgaagactta
     1561 aaaaatctca taaatactgc tcattcaatg gggattgctg ttttattaga tttagttcat
     1621 tctcatgctg taaagaatac tttagaagga ataaatgagt ttgatggaag tgaacatcaa
     1681 tttttccact caggttcaaa gggaaatcat cctgcttggg gtacaaaact ttttaactat
     1741 ggtaaacctg aagtaataca ttttttgctt tcaaatataa aattttggtt aaatgagtac
     1801 cattttgatg gctttagatt tgatggtgta acttcaatgt tatatcataa ccatggtctt
     1861 ggagtttcat ttgatagtta tgaaaaatat tttagtgtga atacagatat tgaagctata
     1921 acatatctcc aatttgcaaa tgaattaata aaagaaatta aacctaattc gataagtatc
     1981 gcagaagata tgagtggaat gcctggtatg tgtatcccta taaaagatgg cggaattgga
     2041 tttgactata gactttcaat gggagtacct gatttttgga taaaaacaat ctctaactta
     2101 tctgatgaga actgggattt aggcaaaatg tggtatgaac ttactactag acgacctgga
     2161 gaaaaaaata taggatattg tgaatctcat gaccaggcat tagttggcga taaaacaatt
     2221 attttttggc tagctgacaa ggaaatgtac tggaatatgg aaataaactc aaataaccct
     2281 gttatcaata gagcaatatc tcttattaaa ttaattaaat taataacttt ttctctagca
     2341 ggtgaagggt atctaaattt tatgggaaat gaatttggac atcctgagtg gattgatttt
     2401 ccacgagaag gcaacaattg gagctataag tatgctagaa gacaatggag cctttcagaa
     2461 gataacaact taaagtataa acaattatta aattttgata aatctatgct tgaacttaca
     2521 aaatacagtg atatttttat ccaaaatagt catgaactta tacatatgga taatgataaa
     2581 aagattttgg tgtacattaa gggcaaatat ttatttatat ttaatttcca ccctaatcta
     2641 atacaatcag ttgatatttc aaagtttcaa aatacaaact acaaaacgat attaaatact
     2701 gatatagtag aatttggagg aaacacaaaa aaagaaaact taagagatta tgatgtgtac
     2761 tttagctcaa ctccaccttc ttctaaaata cctattgcct ctcgtacagc aatagtgctt
     2821 ttagataatg gtatttaaat atgagccaaa aatattagga aactgcaaat ataatccagt
     2881 ataaggcaaa aaaataaaat aatgaaagca tggcaatata cctgttcaac atgctaaaaa
     2941 tacacattga caaatcatta tgtatttgct aagataaaca taccaaatga ttgttttgag
     3001 gagtgagctt tttgggaaga aaaaaagaac ctgataatac tatacaaaaa atacttgata
     3061 tttcacataa gttgttctta gaaaaagggt atgagcagac aacgattcaa gatattgtag
     3121 acaatttaga tggcctttca agaggtgcta tttatcatca ctttaaatca aaagacgaaa
     3181 taattaaggc aatcacaagt cgtttgtata atgatggatt ttatggatat gatgtaaaaa
     3241 atgatgaagg aaagaccgca ttagaaaaat tacaatatag gttgcttcat gcttatgaac
     3301 aacacaataa acaagacatt tttttaatgt catcatcact attgcgtaat cctaagtatt
     3361 tagctacgca gtttgatgag attataaatg atattgtgcc ttggataaaa gcattgattg
     3421 aagaaggaaa tcaagataat tctatgcaag ttaaaaatcc agagattgct gctcaaatgt
     3481 ttggttttct tctaaacaca tggtgtattc caacagttta tccaggtaat ccacaacaga
     3541 tggtagaacg ttttactttg tttggtgagc aagctgcttt tatgggtatt tcttttatga
     3601 atgataagat aatgtgtgaa tatcaaaaat ttgttaataa attttctaaa tagtaaatat
     3661 aaaactgcct taatattggc agttttatat ttacacaaaa caaacattta gttggtattt
     3721 ttaaaaattt gatttatttc ggtacatgca aaaggaggtt gctatgaaca aactaattaa
     3781 agattgtgta aactttttta atgattgtgg cttttcatat tcaatatgtg gtggatatgc
     3841 cctagaatta tttgcgaata tgcatattcg cccacacagt gatattgaca tatggatttc
     3901 tgacacagat aaagaaaaga gcattcagta tatgcttaat caaggatggg atatatatga
     3961 gcccttgggt aattatttat tacgacctat tctcgacctt aacaagcaac atatagagca
     4021 aatttgtgtt ttcgcgatta agcctgattg ctcatttatt gaattaaaaa aagtcgagga
     4081 tgataactat aaaatgaata tacagtgtga cgaacagtta cagttcgatt ttattgaatt
     4141 gatatataat ccacagaaag atggaaaatt tcttttttcc caaaatcaaa gaattataag
     4201 agatatggat aaggccagac tgataacatc agataatatt ccatatatgg ctcccgaagt
     4261 ggttttgttt tgcaaatcaa tatacataga tagagttggt tatcaaaaag acttcgatgt
     4321 aacagtccca ctattatcac aagagcaaag ggattggctt gtaaaggctt taataacagc
     4381 atatccagat ggacatgcat ggattgacca attggcaaat caacattaag ccttttagct
     4441 cccgaatatg acattatgat aatccacact ctaacagttt gttggttttt ctagtatata
     4501 acactcatat taaaataaac actaaaagcc aaataacaat ttaaatacaa aatgttattt
     4561 ggctaattta gtttgatact atttaactat cttttacatt cagttctata atttccaact
     4621 tttaatttgt ggtattatat tcatcttaac agtttgattc tttaaagatt ttctaaattt
     4681 ctcagttgaa gaatctttaa acattttact agaagcactc ttgaggtctt ctatagattc
     4741 ccaatgttgt atcataatcc acttttgaga cttttcatca tataaaagct cagtatcaat
     4801 aaaaccggat tgaatagaat gaaattttaa ttctaagtca tttacaattt ctataaactc
     4861 ttcttttgac aaattttctt ccacattaaa ctcaactatt tctgtaataa ttttcatata
     4921 taaaacctcc aatttatttt cctatatcat atcaaaaaat aaattggagg tattgtaaaa
     4981 aatcgacagt ataattataa atagctgtac tttatatttt ctttaatcgt cttattctca
     5041 ccaataaatt taattggtga cgtccctgaa aattttttaa attcttttat aaagtgcgct
     5101 tggtcatagt actcattttc ataaataaaa tcaaaaagtt catcatcttt ataattataa
     5161 ataagttgat tacttgccat tttaaatctg taaattctct ttaaaatctt aggtgtatac
     5221 cctgtatatt ttaaacaggt tctttccaat gttttaatat ttatatttgt atcatcacaa
     5281 aatgctttta tattgctata tctattaaca tatataaatg aatttaaaag ctctacagat
     5341 ttatttgaaa ttaaatcttc ttctaatatg gataataata cttcttctaa acataaaaca
     5401 actttttcta ttgcttttgt tggatttaat gactcttcta atttctttgc aaatagtttt
     5461 gatactgctt ctaagtcaac aatttgtctg ttaaactctg aaatcggtat ctttaaaaat
     5521 ggatatagac caaatggata aaaagaaatc cctataacac gtatatttcc atgttgaaca
     5581 ataaatccat gtttatccct tattccatta aaatgcatat tactagcagt atagtcttga
     5641 ttttcaaatt tatattccat aacatcagaa agattaagaa taatatctat actgtctgtc
     5701 ggaagtaact tattatttaa cagtatattt gattttgtct caagaaacca aataaacttc
     5761 acccacggct ttaaacgaat atttttgatt gaatatcttg taactgataa cattgtgaac
     5821 taacctctat actaaaattt tttaattatg tactccatct taatattata cagtataatt
     5881 tatgctatcg taaattttag ttcactttat atttatttta tacatttttt taatacttta
     5941 gaaataggaa gcgctattat aagacctatc aatacttgca ttaagttacc cggtattgaa
     6001 gtaagaggta ctacaaaatt accataaagt ataacttctg ttacataata tccaaataac
     6061 atccaaattg atgaaacaca tattcctatt acattgatta aaaaattatt cccgttctta
     6121 ccatttgccc atacaatctt tccaagtaaa taacccataa cgcctctaac tataaaggta
     6181 aatggtgccc acaaagtcca cccagatatt aaatcaaaaa gtgacatacc aatagctcct
     6241 gataaagcac cttttttact tccaaatact attgctgata tgaacaacat tgcagttcct
     6301 aaatgtacaa gcccaccatt tatagatatt ggcaatctta tatttataaa tttagttgca
     6361 ataaatacta atgctattaa tagtgaggtt tccaccatgt ctttcgttgt aaatttttgc
     6421 ttagctgtaa cttccatact atctccccct gtttatttat taaaaataat acttattaaa
     6481 taagtttaac aaagttccat tttctttaaa tcctaatgca cttaaacttt tatccaaaac
     6541 atttagtacg tgctctattt tgtttagatt tgcgttttct cccatatgac ctattcttaa
     6601 aatagtatcc atatattgat ttagtgatgt cgcaacaagt gtattataat ttttaagcat
     6661 gtaatcagta agctttaaag ctcctatgct ttcaggaatt tttatagctg taactgtgtt
     6721 agaatatcct tcttctaaaa atagttctaa accatattcc tcaatagatt ttctaacact
     6781 ataagctatc ttttcatgtc tatttaatac attttctatt ccctcttcta atatattatc
     6841 aagtgctttc tgaacctccc atgactaaag tcacagggtt cctgcttca
//
LOCUS       DAMKOJ010000137         6393 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.146, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000137 DAMKOJ010000000
VERSION     DAMKOJ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6393
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.146"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            271..1215
                     /locus_tag="PC592_003390"
     CDS             271..1215
                     /locus_tag="PC592_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDF4057318.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFITINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGESSVEADREVVKLALKILEKYNNKFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNIHELKVYIEELKIKCEVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1237..1863
                     /locus_tag="PC592_003391"
     CDS             1237..1863
                     /locus_tag="PC592_003391"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDF4057319.1"
                     /translation="MDYLTIALAKGRIEGESFKKLKKMGLGNSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1897..2946
                     /gene="hisC"
                     /locus_tag="PC592_003392"
     CDS             1897..2946
                     /gene="hisC"
                     /locus_tag="PC592_003392"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF4057320.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEIADS
                     NIDLNLYPEDSYSDLKESIIDYINISGVSKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVIDIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKRKDIKKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEERKILYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     AMFIGAIRDILKKEK"
     gene            2949..3527
                     /gene="hisB"
                     /locus_tag="PC592_003393"
     CDS             2949..3527
                     /gene="hisB"
                     /locus_tag="PC592_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDF4057321.1"
                     /translation="MRIWNVERNTLETQISVELNIDGSGKAEIDTGIGFLDHMLTLMA
                     FHGKFDLKVICKGDTCVDDHHSVEDIGIAIGESFKNALGDKKGIRRYSNIYIPMDESL
                     SMVSIDISNRPYLVFNAKFDIQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3529..4134
                     /gene="hisH"
                     /locus_tag="PC592_003394"
     CDS             3529..4134
                     /gene="hisH"
                     /locus_tag="PC592_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDF4057322.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSNIDEIKQADSLILP
                     GVGAFRDSISALEKLGLIPIIKEHVSNGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELVAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4131..4853
                     /gene="hisA"
                     /locus_tag="PC592_003395"
     CDS             4131..4853
                     /gene="hisA"
                     /locus_tag="PC592_003395"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDF4057323.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKINVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIDEIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAVENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEIVSDVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFNIYEKIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4835..5593
                     /gene="hisF"
                     /locus_tag="PC592_003396"
     CDS             4835..5593
                     /gene="hisF"
                     /locus_tag="PC592_003396"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDF4057324.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERTTSLEFVTKVAENISIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKMEDFYQAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKNMGVEVRL"
     gene            5621..6289
                     /locus_tag="PC592_003397"
     CDS             5621..6289
                     /locus_tag="PC592_003397"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDF4057325.1"
                     /translation="MNNKCNDIYTDEVDEFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKEAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDTAKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2599 a          533 c         1267 g         1994 t
ORIGIN      
        1 aaattattta ggaggaaatt atcatggtga gattaaatat agtaaaatta aatacaaaat
       61 taaatcatca ccatcatcat agataaaagg gattgtaata tgaaattaat tcatagacac
      121 aagccctgtt tttagtgtaa ttggtcttgt atctatgatg ggaagtaatt ttaagagaaa
      181 attatagcca tataggtata aagcctatat ggctttttat tgttttaaat ttgcaaatat
      241 aagagtaaat ttaatgaaga gggtgagaat gtgaagtttt tgaggattga agatgaggtt
      301 atttattcta aaaaaagata taaattaaaa agagaaatag ataaactttt tttggatgaa
      361 gaatattttc aaatagaacc acaattattt gaagagtatg atgaatttat aactataaat
      421 aataaaattc cagaagaatc tatggtaaag gttgtaaatg gaaaagtaat ggtacttaga
      481 gctgatataa ctacaagtat aataaaaagt cttgtaccta gatgggaaga tggtttaaag
      541 cttaagcttt tttataattc atcaatatat aaaaataaaa atacagttgg aataaaagag
      601 ataagacaaa taggttgcga gtatttagga gaatcttctg tagaagcaga tagagaagta
      661 gtgaaattag ctcttaagat acttgaaaaa tacaataata aatttatttt agaggttggg
      721 agtagcaagt atattcatgg tttgttagaa gaattaaatt taaataagaa ttgtgaaaat
      781 caaattaaaa atttactata tactaagaac attcacgaat taaaagtata tattgaagag
      841 ctaaaaatta agtgtgaagt aaaagagtta ttatcaaata ttttaagttt acaaggaaat
      901 ttatacaacg ttattgaaaa atcaaacaag ttctattgta ataataagat gaagcaagct
      961 cttgaagaat taaagcaagt gaataattta attgaggaat gtaatttttt agataaggcc
     1021 agatttgact tatcaatgat tacgatgctt gactattatg aaggaattat gtttagagga
     1081 tactatccaa attcatataa agaaattctt agtggtggaa gatacgattc tttaactaaa
     1141 gaatatggaa aagaaattcc agccattgga tttacactaa gtgttgatga attaatgaag
     1201 tatgtatata agtaaagctg agaaggagga attgatttgg attatttgac tatagcacta
     1261 gcaaaaggac gaattgaagg ggaatcattt aaaaaattaa aaaaaatggg tttaggaaat
     1321 agtatagaca cagatacaag aaaactaatt tttaaagacg aagaaaataa aatcatatat
     1381 atacatgtaa agccatcaga tgtagttaca tatgttgaaa aaggagttgc tgaccttggt
     1441 atagcaggta aggatactat tttagagaat gagacggatg tatatgaaat atatgattta
     1501 ggttttggaa aatgtaaatt tgctgtggca ggattaaagg gagatagcat atatagagaa
     1561 gatgaatatc taaaagtggc aacaaagtat cccaatatag cgaaaaagta ttttaaagag
     1621 aaaggtcaaa aaatagaaat aataaaatta aatggttctg tagaactagc tccaatagta
     1681 gggttgtcag atgtaattgt agatattgtt gagactggca atacgcttaa agcaaatggt
     1741 cttgaaatat tagaagatat atgtaatata agcgctagaa ttatatcaaa tagagctagc
     1801 tatagattta aatacgaaca aattcagaat ataattcgtt tgtttgaaga acttgataat
     1861 taaaatataa tggaacttta caaggagggg tttaagttga gagaaaaaga aagtataaga
     1921 gagttaagag gatatgaacc aaatcacgta aactgtaaag taaaacttga tgcaaatgaa
     1981 ggaagtaaga ggttgtttaa ataccttatt aaagagattg cagatagtaa tatagattta
     2041 aatttatatc ctgaagattc ttatagtgat ttgaaagaat ctataataga ttacataaat
     2101 atttctggag taagtaagaa aaatcttcta gtaggaaacg gttcaagtga aataattgat
     2161 ttaataatac atacttttgt agataaagat gaagtaatac tgagtttctc tccaagtttt
     2221 agtatgtatt ctatatatag tcaaataaat ggttctaaat ttataggtgt tgaaagtgat
     2281 gaaaatttag ttatagatat agataatgta attgaaaaag taaaggaaaa taatcctaaa
     2341 atagtaattg tatgcaatcc taataatcca actggaacaa tactaaagag gaaagatata
     2401 aaaaagcttt tagattcaac taatagtcta gtggttttag atgaagcata tatggatttt
     2461 ggagaagaaa gtatgttaag tgatgttttt aagtacgata atctaatagt tcttagaact
     2521 ttatcaaagg cgtttggatt ggctggaata agaacaggat atatgttatc taatagcagt
     2581 ttaataaatt ctgttgaaaa agtaagacct ccatataatt taaattcatt gtcagacttt
     2641 attgctacaa gagcacttag aaataaagat gtggtaaagg cttatataaa ggaagtaaaa
     2701 gaggaaagaa aaattttata tgaagagatg attggtatgg gaattaaggc atataaatca
     2761 caagcgaatt ttatattgtt ttactctgaa atcgaaaatt tatcacaaaa acttattgat
     2821 agaggagttt taataagaaa atttggtgga aagttagaaa attattatag ggttacgatt
     2881 ggtgataaag aagaaaatgc tatgtttatt ggagctataa gagatatttt gaaaaaggag
     2941 aaataggtat gagaatttgg aatgtagaaa gaaatactct tgaaacacag atttcagtag
     3001 aattaaatat tgatggctct ggtaaagctg aaatagatac tggaatagga tttttagacc
     3061 atatgcttac cctaatggca tttcatggca agttcgattt aaaagtgatt tgtaagggtg
     3121 atacatgtgt agacgaccat catagtgtag aagatatagg tatagccata ggtgaatcat
     3181 ttaaaaatgc tctaggtgat aaaaaaggaa taagaagata ttctaatatc tatataccta
     3241 tggatgaatc tctatcaatg gtatcaatag atataagcaa cagaccttat cttgtattta
     3301 atgctaaatt tgatatacaa atgattggta gtatgagcac tcaatgcttt aaagaatttt
     3361 ttagagcttt tgtaaatgaa tctagagtaa cattgcatat caatctctta tatggggaaa
     3421 atgaccatca taagatagaa agtattttta aggcatttgc aagagcttta aaagaaggta
     3481 gtgaaatagt ttctaatgag atagcatctt caaagggggt tttgtagaat gaatataata
     3541 gtagattatg gtcttggaaa tatagattct gtgtctagag gtttcagaaa agctgggata
     3601 gaaactaaaa tttctagtaa tatagatgaa ataaaacagg ctgattcact tatacttcca
     3661 ggtgttggag cttttagaga ttctataagt gccttagaaa agctaggatt gataccaata
     3721 ataaaagagc atgtttctaa tgggaaattt atgataggta tatgtctagg aatgcaatta
     3781 ctttatgaaa aaagttatga gtatggagaa tatgaagggt taggacttat aaaaggaagt
     3841 attgataaac tggatataag tttaaaagta ccacatatgg gatggaataa tttaaaattt
     3901 aataaggcaa atgatgatat acttaaatat ataaacgaag atgattatgt atactttgtt
     3961 cactcatatt atgcaaattc atcaaatgaa gaactagttg cattttcaga atatgagaag
     4021 aaaattcctg ctattgttag aaaaggcaat gtatatggta tacagtttca ccctgaaaaa
     4081 agtggagaag taggtttaaa tatattaaga gcatatgggg agatgataaa atgataatat
     4141 ttccagcaat cgatataaaa gataataagt gtgtgagact cacacaagga gaatttgaca
     4201 aaataaatgt atattatgat aatccgttag aagtagcata taaatggaaa aatgaaggag
     4261 cagaatatat acatatagta gatttaaatg gtgctagaag tgaatttggt gtaaatacaa
     4321 aaataattga tgaaatagca aacaatatag atatacctat tcaagttggt ggtggagtta
     4381 gagataagga aaaagttaaa agtttaataa atgctggtgt tactagagta atattaggta
     4441 gtatagcggt tgaaaatttg aatttggttg aagaattggt caatgagtat aaagagaaaa
     4501 tagtggtttc tatagatgct aaagatggaa aggtagcagt tagagggtgg gaaattgtaa
     4561 gcgatgtaga ctcattaaca ttgtgtaaac aacttgaaaa gataggtgta caaactattg
     4621 tttatacaga tatatcaaaa gatggtatgt tgcaaggacc aaattttaat atatatgaaa
     4681 aaatagcaaa ggaaacatca ttaaatgtta ttgcttctgg aggcgtaact tctatagaag
     4741 acgtaaaaag actaaaagct atgaatttat atggtgcaat aataggtaaa gcgctttatg
     4801 ataaaaagat agactttaag gaggcacaac aattatgctt actaggagaa taataccttg
     4861 tctagatgtg agaaatggaa gagttgtaaa aggaaaaaaa tttaaagata tagtagatgt
     4921 tgatagtcca gaggtgcttg gaaaatttta tagtgattgt ggtgcagatg aactcgtatt
     4981 ctatgatata actgcatcaa atgaagagag aactacgtct ttagaatttg tgacaaaagt
     5041 tgcagaaaat ataagtatac cattttgtgt tggtggagga gtaaataaat tagaagattt
     5101 cactgatatt ttaagaaaag gtgctgataa agtttctata aattcatcag cagtcaaaaa
     5161 tcctgaatta ataagggaag cttcattaaa atttggagca caatgtgttg ttttatcgat
     5221 agatgcaaag aaaaatgaag agggttcatg gagcgtatat gtaaaaggtg gaagagaaaa
     5281 aactaatctg gatgcaattg aatgggctgt taaaggtgta gaacttggag caggagaaat
     5341 cgttgtaaat agtatggacg aagatggaat gaaaaatgga tatgatattg aattattatc
     5401 aaagataact tctttagtaa atgtacctgt tatagcatct ggaggtgctg gaaaaatgga
     5461 agatttctat caggcggtta ataaatctaa tgtagatgga attttagcag catctgtttt
     5521 tcattttggt gagataaaaa taaatgattt gaagaaatat ttaaaaaaca tgggtgtaga
     5581 agtaagatta taagttaaat attgaaagga gattagaaat atgaataata aatgtaacga
     5641 tatatacact gatgaagtag atgaatttat aagaagtata aagtttgatg ataaaggatt
     5701 agttcctgtt gttgttcaag aggtagtgag taaagatgta ctgatgttag catatatgaa
     5761 taaagaggct ataaagaaaa cattaaaaga taaagtggct tgctatttta gtagaagtag
     5821 acaagaactt tgggttaaag gtgagacatc tggtaatact caaaaagtag ttaagatgtc
     5881 ttatgattgt gatgtagata cgatactact ttttgttgaa caaactggtg tagcttgtca
     5941 tacaggaaat tattcttgtt tttacagaga cttgtttgat gatactgcta aaatggaact
     6001 tgaagtacaa acaaatatat tgaaagaatt atatgattta attaatgaaa gaaaaaataa
     6061 tccagttgaa ggttcttata ctaattatct ttttgaaaaa ggaatagata agattcttaa
     6121 aaaagtaggt gaagagagta gtgaagtaat tatagcgtca aaaaataccg ataaaagtga
     6181 acttatttac gagattagtg atttagtata tcatacattg gttttaatga tagaaaaagg
     6241 tgttgaaatt gatgaaataa aaaaagaatt acttaaaaga agaaaatagg atagaataga
     6301 ttaatgctaa taagaaaata taccgctttt aataaaaagt ggtatatttt tttattttat
     6361 attttcgatt tatagaataa tatttgaatt act
//
LOCUS       DAMKOJ010000138         6219 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000138 DAMKOJ010000000
VERSION     DAMKOJ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.147"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            217..1239
                     /locus_tag="PC592_003398"
     CDS             217..1239
                     /locus_tag="PC592_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF4057326.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSSL"
     gene            1299..2306
                     /gene="gap"
                     /locus_tag="PC592_003399"
     CDS             1299..2306
                     /gene="gap"
                     /locus_tag="PC592_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF4057327.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2528..3730
                     /locus_tag="PC592_003400"
     CDS             2528..3730
                     /locus_tag="PC592_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDF4057328.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEEMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEGYMGLDMGPKTIANFVKTIKESKTIVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3756..4499
                     /locus_tag="PC592_003401"
     CDS             3756..4499
                     /locus_tag="PC592_003401"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDF4057329.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCRVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4508..6040
                     /locus_tag="PC592_003402"
     CDS             4508..6040
                     /locus_tag="PC592_003402"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDF4057330.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKATSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAVKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYENAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         2475 a          731 c         1252 g         1761 t
ORIGIN      
        1 aataaaaaaa tatatataaa aagccttata taaaaagaaa aaatactgtg atttgaaaat
       61 ggtggagaaa tattttataa aataaaaaaa taaaaaagtt tttgaaaaac tattgaaatc
      121 tatacgcaaa tcctataaaa taaaaatatc ttgtgggact taaataaaca ctagggacga
      181 aaaaagtccc gaaaggaaag caataaggag tatgttatga agaacttatt agaaattcaa
      241 aagaaattga ttccacaggc aattgaactt atggaaagaa gatactctat tttaagacaa
      301 atatctttaa gtgaaccaat aggtaggaga acattatcaa atgtattaga gattagtgaa
      361 agaataatca ggtcagaaac agagttttta aaagaacaag gacttataga cgtagctgta
      421 tctgggatga ctatcactaa agaaggttct gatttgttag ataaacttaa ggacatcatg
      481 agtgacatca tgggattgtc taagttacaa gatagagtca gagaaaagct tggaataaaa
      541 agggtaatac tagttcctgg aagctgtgat gaaaatggaa gtttattaaa agatgtaact
      601 agatatggat gcgagtattt cttaggtatt ttaaaagatg gagatatcgt ttcaataaca
      661 ggaggaagca ctatgttgga gttttcaaac gttattaaaa ctgataagag atacccaaat
      721 tctacaatag ttccagctag aggaagcatg ggaactgatg tagagatgca atctaataac
      781 atagttgctt caataagtaa gaaattacat tctaattgca aacttttaca tataccagat
      841 gagttggatg aaagtgcaat gaaaactctt agccaagtgc cagagattaa gacaactttg
      901 gagtatatta aaagaacaga cattttagtt tttagtatag gtagagcaga tgtcatggca
      961 aagagaagaa aacttccaga agacaaagtt gatgagatat tatctaaaaa tgcagttgga
     1021 gaagcatttg gatattattt caacaaagat ggagaaatag tttacaaact gaatactgtt
     1081 ggaattgatt tagaaacagt caaacaagta aaagaaacta ttgcaatctt tgcaggtact
     1141 gaaaaagtag aagccttatt agccatatca aatatgcata aaaacatggt tcttgtaaca
     1201 gatgaagaaa gtgcttataa gatattgtca tcattataaa agtcaagacc tagcacagag
     1261 ctagaaaaca tacatttact ttataggagg tagcgaaaat ggttaaagta gctataaatg
     1321 gatttggaag aataggaaga ttagcattaa gaaaaatgat ggagcaacaa gataagtttg
     1381 aagttgttgc aataaacgac ttaacagacg ctaaaatgtt agctcattta tttaaatatg
     1441 atacagctca aggaagattt aacggagaaa tagaagttaa agaaggtgct tttgtagtaa
     1501 acggaaaaga aataaaagta acagcagaaa gaaatcctgc tgacctacca tgggctgaat
     1561 taggagtaga tatagtatta gaatgtacag gattctttac atctaaagat aaagctgaag
     1621 ctcatataca agcaggagct aagaaagttg ttatatctgc accagctact ggagatttaa
     1681 aaacaatagt attcaacaca aacagtgaca tattagatgg ttctgaaaca gttatatcag
     1741 gagcttcttg tactactaac tgtttagctc caatggctaa agtattaaac gataaatacg
     1801 gtatagaaaa aggattaatg actactatac atgcatacac taatgaccaa aatactttag
     1861 atggtcctca tccaaaaggt gatttaagaa gagctagagc tgctgctgga aacatagttc
     1921 caaacactac aggagctgca aaagcaatcg gtttagtaat accttcttta aaaggaaaat
     1981 tagatggggc agcacaaaga gtaccagttg taactggttc aataactgaa ttagtttgta
     2041 cattaggaaa aaatgttaca gttgaagaaa taaatgcagc tatgaaagaa gcttcaaacg
     2101 aatcttttgg atatactgaa gaaatgttag tatcttctga cataatcgga ataagctacg
     2161 gttcattatt tgacgctact caaacaaaag ttatggaagt agatggaaaa caattagtta
     2221 aagttgtttc ttggtatgat aatgaaatgt cttatacttc tcaattaata agaactttag
     2281 gatactttgc acaattagca aaatagtcag ttttgagaaa atagaaaagt agattgacaa
     2341 agtccgagtt tgtagtttaa tactacggac tcaggacttt ttttaagaaa aaatatataa
     2401 aatacaccta aataatgtta catactatat ataaaaatat gataatatga tatatttaat
     2461 agggtaaaag tatgtactat attatacttg gcaataaaaa attactttat taaaaggaga
     2521 gatatttatg tcaatgctta acaaaaaaac tatagaagat attgatgtgt gcggaaaaaa
     2581 agtattagta agatgtgact ttaatgtgcc attacaagat ggtgtaatta ctgatgaaaa
     2641 tagattgaac ggagctttac caactattca atatttaatt tctaaagggg caaaagttat
     2701 attatgctct cacttaggaa agccaaaagg agaagctaaa ccagaattat ctttagcacc
     2761 agtagcgaag agattatctg agatgttagg aaaagaagtt gtatttgcag cagacgataa
     2821 tgttgtagga gaaaatgcaa agaaagcaac tgaagaaatg gaaaacggag atgtagtatt
     2881 attagaaaat actagatata gaaaagaaga aactaaaaac gaagagaatt tctctaaaga
     2941 actagcatca cttgctgaaa tatttgtaaa tgatgcattt ggaactgctc atagagcaca
     3001 ttgctcaaca gttggtgcag gtgagttctt acaagagaga gtttgtggat atttaattca
     3061 aaaagaacta aaattcttag gagaagctgt tgcaaaccct gtaagaccat ttacagctat
     3121 acttggagga gctaaagttt ctgataaatt agccgttata aatgaattat tagaaaaagt
     3181 tgataatcta ataataggtg gaggaatggc ttatacattc ttaaaagctc agggttatga
     3241 agtaggtact tctttacttg aaatagacaa agttgaatat gctaaagaaa tgatggaaaa
     3301 agctaaaaat aagggtgtta acttattatt accagtagac gttgttatgg cagaccactt
     3361 tgcaccagat gctactccga tagtaacaga agatgctaat gtaaaagaag gttacatggg
     3421 actagatatg ggacctaaga ctatagcaaa ctttgtaaaa actataaaag aatcaaaaac
     3481 tatagtatgg aatggaccaa tgggagtatt tgaatttgaa aactttgcaa atggtacatt
     3541 atcagtagct agagctatgg cagagctaac tgatgcaact actgtaattg gtggtggaga
     3601 tagtgcagca gcagttaatc aattaggatt tggtgataag atgactcacg tatcaacagg
     3661 tggaggagca tcactagaat ttttagaagg taaagaatta ccaggtattg cagcattaga
     3721 taataaataa actaatatat agaggagatt gtaaaatgag aaaacctata attgcaggaa
     3781 actggaaaat gcataaaaca ataaaagaag ctttagaatt tgtaaatgaa gttaaagata
     3841 aagtaaattc tgataaagta gaagctgtta tatgtgcacc atttacttta ttaaaggatt
     3901 taaaagaagc tactaagggt acaaatataa agataggtgc tcaaaatatg cactttgaag
     3961 aaaaaggagc atttacagga gaagtttcac ctcttatgtt aaaagaaata gatatggact
     4021 atgttgtaat aggacattca gaaagaagac aatacttcaa tgaaactgat gaaactgtaa
     4081 ataagaaagt tttaaaagca ttagaagtag gaatagaccc aatattatgt gttggagaaa
     4141 ctttagagca aagagaagct ggaaaaacta aagacgtttg tagagttcaa gttgaaaaag
     4201 ctttagaaaa tgttcttaag gatgatttag caaaagtagt tgttgcatat gagccaatct
     4261 gggctattgg aactggtaaa actgcaactg ctgaagatgc taatgacgtt atatcttata
     4321 taagagaagt tataaaagga ttatatggag aattagctaa tgaggttaga atacaatacg
     4381 gtggaagtgt taaaccttca aatgtagccg aaataatggg tcaaagtgat atagatggag
     4441 ctttagtagg aggagctagc ctagctagta atgattacct agaccttgtt aatttctaag
     4501 gagtgaaatg atgaaaaaac cagttgcttt aattattatg gacgggtttg gatacaataa
     4561 ggatgttaaa ggaaatgcaa ttgctgagtc caaaactcct aatttagata gaataaaaaa
     4621 agagtatcca aacacattga taaatgctag tggtcttgat gttggtctac ctgatggtca
     4681 gatgggaaat tcagaagttg gtcacactaa tataggtgca ggtagaatag tatatcagga
     4741 tttaactaga ataacaaaat ctataaaaga tggtgacttt tttactaata aagttttatg
     4801 tgaagctatg gataatgcaa aagaaaattc tcttcatgta atgggacttt tgtctgatgg
     4861 aggagtacat tcacatatag accatcttaa ggctataatc aaaatggcaa aagataaagg
     4921 tgtacaaaag gtgtatgttc atgcatttac tgatggtaga gatactgacc ctcaaagtgc
     4981 attagaatac gccaaagaag tacaagctag tatggatgaa attggagtag gtgaatttgc
     5041 tacagtttct ggtagatact acgctatgga tagagataag agatgggaaa gagtagagct
     5101 tgcatacaat gctatggtta gaggtattgg tgaaaaagca acttctattg aagaagctat
     5161 tcaaaactct tatgatgatg gaaaaaatga tgagtttata atgccaacag ttattatgaa
     5221 agatgataaa ccagttggaa gtataaagga aaatgattca attatattct tcaactttag
     5281 accagataga gctagacaaa taactagagc tttagtttgt gaagagtttg atggatttaa
     5341 aagagaagat attaaaaact tctttgtatg cttaacagag tacgatataa ctatagagaa
     5401 tgtgcatata gcatttggac ctcaatcttt agccaacact ctaggtgagt atctagctaa
     5461 aaatggaaaa actcaactta gagctgctga aactgaaaag tatgcacatg taactttctt
     5521 cttcaatggt ggagtagaag agccaaataa aggtgaagaa agactattaa taccttctcc
     5581 aaaggttgca acttatgatt taaaaccaga aatgtcagca tatgaattga cagataaagc
     5641 tttagataaa ttaggagaag ataagtttga ctttatagta ttaaactttg ccaatcctga
     5701 tatggtaggt cacacaggaa gtatagaagc agctgtaaag gctgttgaaa ctgtagacac
     5761 ttgtgtagga aaattgatag ataaaatagt agagttaggt ggaagtgcaa taataactgc
     5821 tgaccacgga aatgctgaat atatgttaga cccagaaaca ggaaaaactg taacagctca
     5881 ctctattaat ccagtaccat ttattgtagt tggtcaagaa tatgaaaatg caaagttatt
     5941 ggatggagga agattatctg atatagcacc aactgtttta gatatgatga agttagaaaa
     6001 gccagaagaa atgactggtc attcacttat ttcaaaatag tcgattatga taagtataaa
     6061 ataagatata agctacaata taaatttaaa aataacacag tttaggttta ttttgtaagg
     6121 tctagatttt atgatataag atttagcttt tgtaaggtct ggatattgta aggtgtagat
     6181 gaaagtatat tttataatat ttacaatata gacaattta
//
LOCUS       DAMKOJ010000139         6139 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000139 DAMKOJ010000000
VERSION     DAMKOJ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.148"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            86..820
                     /locus_tag="PC592_003403"
                     /pseudo
     CDS             86..820
                     /locus_tag="PC592_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(1069..1416)
                     /locus_tag="PC592_003404"
     CDS             complement(1069..1416)
                     /locus_tag="PC592_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HDF4057331.1"
                     /translation="MSKSNDVLDIVFKITNGLEYEVDENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(1403..3334)
                     /locus_tag="PC592_003405"
     CDS             complement(1403..3334)
                     /locus_tag="PC592_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HDF4057332.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGVAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSTGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVS
                     GMTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGS
                     KNEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGS
                     LPWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEK
                     EKEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVL
                     VVLTALPIILSKVKNNEQE"
     gene            complement(3745..5934)
                     /locus_tag="PC592_003406"
     CDS             complement(3745..5934)
                     /locus_tag="PC592_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDF4057333.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDKDILIEDL
                     EFVCKEEEKVLLEDFNDNQYEVPHDKSYVDLFREQVKVTPSNIAARDENRNLTYKELD
                     EVTDKLAGYLNYIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLEYELTEKITPSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSINATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYKKRNYELYNEYGPTEFTVISTSFHVDREYGKIPIGKPISNTYAYVLDKKNKLCPI
                     GVPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDEGDMYICAYYVIGDED
                     SDKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE"
BASE COUNT         2131 a         1058 c          699 g         2251 t
ORIGIN      
        1 gcctgtggag aattagtaag acatatttta gtatgcaaaa ttctatgaag caggaaccct
       61 gtgactttag tcatgggagg ttcagatgag ggctatagac tatgtaaaag aagctagtga
      121 ctatatagaa acttcagatg gtactaggat tacagcttct caaatgtgtg aaagattcct
      181 ttttaatggt actatgcagt atactttgat aggtaaatta tctggtggtg aaagaagaag
      241 actacacctt cttaaaatcc ttatgacagc tcctaatgtg cttcttttag atgagcctac
      301 aaatgattta gacattgaaa ctcttaaaat attagaagaa tacttagacg aatttaaagg
      361 tgtagtagtt acagtatcac atgatagata tttcttagat agaatttgta ataaaatatt
      421 ttcatatgaa ggtaatggaa aaattcatat ctatacaggt aattacagtg attatcttat
      481 ttatagagag attcaaggaa ttgaatttga agaatctaaa aaagaatctg ttaaaaaaga
      541 tgactctatt accccaaaaa aagaaaaacc taaaaatgat aaaaagctta aattctcata
      601 taatgaacaa agggaatttg aaaatattga ctcagatata gaaaaacttg aatctaaaat
      661 tgcaacactt gatgaaagta cttccaaatt ttcaactgac tttactaagc ttcaagaaat
      721 tttaaatgag aagtctaagc ttgaaaaaga acttgaatat aaatatgaaa gatgggaata
      781 tttaaataat ctagctgatg aaatagctaa taataaatga tattaaaata atcttaagtt
      841 taataagttt tgctttaaat ctgtacttta taaatatttt aaagagtgtg tctcaaaatg
      901 aactttttag tttacgagac actcttttta tatgaaatca aatatatttt catcatttca
      961 acaatataaa agaggcttat ctctattttg agacagcctc tttcataatt tttataatta
     1021 ccttctaatt tatatgctct aatatatcta taataattct tattatatct atatatccag
     1081 tctttcaata tagtgacaat taacttcaat atgatttaaa aatactaaca acctttcata
     1141 aagtggatga gattcttctc catatttagc ttctaggttc ttgcctattt ctctaacagt
     1201 tctttgacca tcaatttgta aaaaaacaaa acttgaatat tcatctagtt ctattttttt
     1261 gtatttaggt attctagctt ttaatttcct aaaaaacttt tgaattttat ggtcctgttt
     1321 ttcaagtata gtaacaacac tattttcatc tacttcatat tcaagtccat tagtaatttt
     1381 aaatacaata tctaaaacat cattactctt gctcattatt ttttacttta gataaaataa
     1441 taggtaatgc tgtaagcaca actaaaacta ctaataaagc aattgccatt gaatttgttg
     1501 cagcaaatcc acttggtacc tttggagtta caactccagt tacttgtagt attataccta
     1561 ttaaaccaat gatagaacca ccagcaacaa gaccagaaga taaacttata ccattagaaa
     1621 ctttaacttc tttttctttt tcagttttag atactaattc aacaaataaa cgaatcaatg
     1681 ctccaactaa tattatagaa gttgttgcaa ttggtaaata gaatcctata gctatagtca
     1741 ttattggtaa atttaatgca tatagaacga ttgccataaa tactccaacg ataatcataa
     1801 cccaaggtaa actacctgac atgataccag aagttaatgt tgacattaag tttgcttgtg
     1861 gtaatgcaaa ttgtacatta tcaccagttg ctctaagttg gtcagaaagt aataaaatta
     1921 ctcctacaac aactataaca ccaactatac ttgcaattgt aaagtaacgt tgcatttcgt
     1981 ttttgctacc accaataata taagttactt tttgagattg agtataacct ccagctatcg
     2041 caatagcaac aactataaat gaaccaaata aaagtaatga tttattagct tctaaatcag
     2101 tccagcccat tataacaaac actaatgtta caataactag agaagctata gtcataccag
     2161 aaactggaag atttgatgtt ccgattgttc ctgttaaacg accagctact atgacaaata
     2221 ataaagataa taaaagagat atgatagctc caataattgc cataacaatg ttaccaccag
     2281 aaattaagaa tgctgctaaa aatccgataa ctactccacc taataaaagt atcatttgta
     2341 tagatgaacc ttcttctcct tctccagtac ttgacttagc tttaagtgtt tcttttatag
     2401 aagcgattat agttggtata agttttattg caccaataat acctccacaa agcatcatac
     2461 cagcacctat atattttaca taactactag atattgctcc aacatccatt tggttaagag
     2521 gcattgcagg attattccat accatagctc catctttagc catatctgta aagtatccta
     2581 ttaaaggtgc tataccaaag tttgataaaa tacttcctgc aaacattgtt aaagaaactt
     2641 caagccctac tataaatcca attcctaaaa gtagaggatt tacttcaata tcaaatttcc
     2701 atttgtagaa tttgcttcct acaagactca ttacattgtt tgctacattt aagaatgaac
     2761 cagttaatac agtaataaat ccacttatta caaatccaat tcccatgtat ttaattgaat
     2821 ctccaccagc ctctgaagca acaagtgtct cagatatggc cattgattct gggtacataa
     2881 gtttaccatg ttcttcaact attagatagt tgtgaactat agcagcaact cctatcccaa
     2941 ataaaactcc accaactcca acagctaaac cttctaggaa tgtaatttgg cttccaatta
     3001 atataactgc tggtagtacg aaaataaatc cacttgcaac agattctcca ccacttgaca
     3061 taccttggat taagttcttt ccaagaatac cctttgaacg agcaaatgct ccaacaaaag
     3121 cagaacctat tatagctcct ggaatacctg cggcaactgt aagaccagct ttcattccag
     3181 agtaagttgt agatgcggca aaaatggcag ctaaaataat accgataatc agtacagcta
     3241 catttccacc ggttctggac ttatctgtga tgtatggaac gtaatctttt ccactaacct
     3301 caccataagc acccttaggt aattttttgt tcataaaatt ttcacccctt ttcaatttgt
     3361 atatattata acatatatac atataaaact taacttttta ttattttaca aatagcgagc
     3421 caaaactact aaaatttaat actatattat taatttctac ttttagatat ttttatgcta
     3481 attttctttt tatttttcaa ttctactaaa aactattaag atataaaaca aaaaattttt
     3541 ttaatgtaaa attaattttg taaaaaaagt gctttaaaac acaaaaaagt ataaaaaata
     3601 caataatcat tcttataaat aaattttcac catagtaaat atatacagaa aattcttttt
     3661 tttacatcaa ttgattttct tataaaaata ggtgtcataa agaaatatat gaaatcactt
     3721 tacaacacct gtcataataa aaaatcactc tggtagtgct tttttattta cttttcctat
     3781 tggtgtaact ggtattttat ctatcctcat tattattgtt ggaatcatat atggaggtag
     3841 atgctcgttt aaatattctc taatagttct ttcatttatc ttatcactat cttcatcacc
     3901 aattacataa tatgcacata tatacatatc cccctcatca tttgttctcg atatacagac
     3961 aacactttta atttctgtaa tattatttat tatattttca atctcatata gctctatcct
     4021 aaactcatca atttttactt gattgtccat ccttccaata taatctaaat ttccatcatc
     4081 taaccacctt actaaatcac cagttctata cattaactta ttatgttcac aagttttgta
     4141 aggattctct acaaatactt gctctgttag tcctttttta tttaaatatc ctcttgatat
     4201 ttgaatgcct gataggcata actctcctgg aactccaatt ggacatagtt tgttcttttt
     4261 atctaataca tatgcataag tattagatat aggtttccct attggtattt ttccatattc
     4321 tctgtcaaca tgaaaagaag tcgatataac agtaaattct gttggtccat actcattata
     4381 cagctcataa ttacgctttt tatatccttt taatctttct cctccagtct gtacaactct
     4441 aagtgagtta ttattgcaat tttgtataaa taaccttgca aacgctgttg gcaacgctag
     4501 tatagttata tcattttcct cacaatattc atttactgta tattcatcaa atttagcttc
     4561 ttcaggcata atatctattg atgcacctac aagcaaataa gggaatagtt gtttcattac
     4621 agcatcaaaa ctgaaactta agtatatacc acatatatca ttttctgtag cgtttataga
     4681 ttttacacta tagtaacaca tatttactaa actcttatgc tctatagcta tggtctttgg
     4741 cctaccagtt gaacctgagg tagatatcgt atatgcacaa tttgatggtg ttattttttc
     4801 agttaattca tattcaagct taaacatttc ttcatcattt atatcgagta ctatggtatt
     4861 ctcatttaca accttacttt ttagttcgtc tgtagttatc actacttttg cattactatc
     4921 ttcaagaagg taattcaatc tttcttctgg attgcttgtg tctattggaa aaaatgctcc
     4981 acctgacttc ataatcccta tagctgtaat aattatgtta atatctcttg gtaacattac
     5041 agctactatg tcttcacttt ccactcctat ataatttaaa taacctgcaa gtttatcagt
     5101 tacctcatcc aattctttat atgttaaatt tctattttca tccctagcag ctatattact
     5161 aggtgttacc ttaacttgct ccctaaataa atcaacataa cttttatcat gtggtacttc
     5221 atattgatta tcattaaagt cttccaataa tactttttct tcttccttac atacaaattc
     5281 taaatcttct attaaaatat ctttgtcttc tattatttgc tctattatat aatcaaattg
     5341 atttaaaatt cttctaatag tctctctttt atatatagat ggtttatact ttatttttat
     5401 tttaagcgct ctcttagtat atactattac agataaatca tatccctttt tttctatgtc
     5461 ataatcatat gataaatcaa aacttttagc tataaatatt gtgtttataa gcttagtatt
     5521 tagatgattt ttattctcta tatctgataa taaatagtat ccatactcta aagacctgct
     5581 ccactgcctt tttagctttc ttacaacatc tataaatttt tcactttgtc taactcgtac
     5641 tcttattgga attatattca ttgttttacc aaaaactaca tcatcttcat atatatactt
     5701 ttgaagtata agaccatata tagtttctat gatagagtct atgctaatat tgttcacttt
     5761 agaatattga attaaccttt catgtttctc aatattcatc ttaaaaacct catctactac
     5821 ttcatcagaa caatctttat aaaaaaaatc atttggaatt tttgctatat tcgtataatc
     5881 atctaacaaa tccatccaat aattcatagc tcgttctaaa ttaacttcat acatatcaaa
     5941 attccccctt actactaagt ctatataaaa aattcttttg gaattttatt tttcacaata
     6001 tataatatat taataataca tatgcaagct ctaaaagcat gagcttgcat aaaattacac
     6061 ctattattat ggctactaaa ttcgtaatat ttacaatgtt taaaatatat tataacacat
     6121 atatgatttt atttttcta
//
LOCUS       DAMKOJ010000140         5981 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000140 DAMKOJ010000000
VERSION     DAMKOJ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.149"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            123..1490
                     /locus_tag="PC592_003407"
     CDS             123..1490
                     /locus_tag="PC592_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDF4057334.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILSYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIITFICREHECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            1515..2123
                     /locus_tag="PC592_003408"
     CDS             1515..2123
                     /locus_tag="PC592_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HDF4057335.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHEKLFIEIAIEAFKNFDELIIISNNEELYSKYDIRVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNSEVVERIANKMKDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            2171..2542
                     /locus_tag="PC592_003409"
     CDS             2171..2542
                     /locus_tag="PC592_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDF4057336.1"
                     /translation="MNLLKCDSWAVILNNSNKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            2700..3038
                     /locus_tag="PC592_003410"
     CDS             2700..3038
                     /locus_tag="PC592_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDF4057337.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            3505..4008
                     /locus_tag="PC592_003411"
     CDS             3505..4008
                     /locus_tag="PC592_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HDF4057338.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNRIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEILRGQVTE
                     CATKKSK"
     gene            4055..5014
                     /gene="moaA"
                     /locus_tag="PC592_003412"
     CDS             4055..5014
                     /gene="moaA"
                     /locus_tag="PC592_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDF4057339.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKVRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRILELEKCGLNKVNISLDSLKEYKYKSITRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            5018..5488
                     /gene="moaC"
                     /locus_tag="PC592_003413"
     CDS             5018..5488
                     /gene="moaC"
                     /locus_tag="PC592_003413"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDF4057340.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDIDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            5520..5951
                     /locus_tag="PC592_003414"
     CDS             5520..5951
                     /locus_tag="PC592_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDF4057341.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENITTEGIEVFSLPIGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVQVLKEGIINVNDSIDVI"
BASE COUNT         2516 a          486 c         1107 g         1872 t
ORIGIN      
        1 atatatgaag gtttttggag aatacttact tatgatagga aaaaatgtta aaataatagt
       61 gtaatcaaat ataaaggact gaaataatta acagttatta aatattagga gtgtaaaaat
      121 ttatgggatt aaaagaattt gattttattg aagagtctat cgatatgttg aggacaatgt
      181 caccaacatt agaaactata tcagatgaaa tagaagagta ttttgaaaat atcttggatg
      241 aaaagaatca agaatatata aatgtaacct ctagaataaa atcagaatca agtttaagag
      301 aaaagataat tagaaataga tatttaaaaa aatatggaga agcaagtaat cttattcata
      361 atgtatctga cttaataggt ttaagaatcg agtgcagatt tattgaggat gaaaacaaaa
      421 tatatagact tttgagaagg tattttaata aaacagatga caaaataaac tattataaca
      481 aagagaataa gaatattaaa ttaaaactat ctgagaggca acccaataag caaaaaaatg
      541 gatttgaaat atataaaata gatggagttt tcgcgtattt agatagagaa gtaaaatttg
      601 aacttcaaat taaatctctt gtaaatgtgt tttggagtga aatagaacat aaaataattt
      661 ataaaaacaa tacatattta cttgctgaca aatttataaa ggatatgatg gattctataa
      721 agaataatct tactatgata gataatcagc ttttaagtat ttataaaaac tttcattcag
      781 ggaagtcttt taatatgaaa gtgagtaaaa aagaaattga aaaattattt gcgaaactag
      841 tatatgacgc tttttctgaa aagatgaata aaagtatagg ttttgttgta gattttaaaa
      901 aaccatgtga gactatattg agctattctt ttaataagca agatataagt gatgaagttt
      961 taggtaattt tatgcttgat gagtttgcaa gattaaatga aattgtaaac aaggatatag
     1021 attttaatga gcaaatagaa tttgaaagag aaccgacatt tgatgataag ttttgtaaag
     1081 acctaggaaa tcattttaga agtagattaa acacagaatt tccatggaac ctgtttttta
     1141 gaatattatt tgaaatagag ccatataaca ataccaaaga ctttgaaaat tttgtagagt
     1201 ttataaaaga aaatgtgcta ctagaagaaa atagggaaca attattatgc caatttgaag
     1261 aagatagcaa acttataatt gaagatatat atgattgcat atttaatagt ataagtgaga
     1321 ttgatagtgt tgaaatttta tataattata atcttgaaaa aataaacttt acatcaagtg
     1381 aaattataac ttttatatgt agagaacatg agtgttatgg tgaatactta gaagaaaaag
     1441 aaaagcttat gaatacattt aaagaaaaga ttattcaaat ctttgaataa taagtcaatg
     1501 ctgaagtggc gctaatgcgc catttttcaa atatatatga attaagtaaa attattttgg
     1561 aggaggcgat ttgtatagag aaaacaggtg taattttggc agggggaaaa aattctagaa
     1621 tgggtagaga taaagccttt ctagagttac atgaaaagct ttttattgaa attgcaatag
     1681 aagcatttaa aaactttgat gagttgataa taatatctaa taatgaagaa ttatattcta
     1741 aatacgatat tagagtttat aatgatatag taaaagatgt tggtccaatt ggaggaatat
     1801 atactgctct tgaatatgca aagtatgata tagttacaat tgcatgtgat atgccatatc
     1861 taaatagtga agtagtcgaa agaatagcta ataaaatgaa ggataaaagt gtgatttcag
     1921 tgacaaatgg aaagttacaa ccattgtgtt ctggatataa aaagagtata ataaataaag
     1981 tatctttatg tataagggaa aatgatttaa agctcagaag ctttatagat aaaatagata
     2041 aaagctatat atactttgat gaagaagatt tatttttaaa tgtaaacact gttgatgagt
     2101 acaaaaaatt aactaaagtt taattagcta tggttgtaaa atagagtagg atttatatgg
     2161 aggagagttt atgaatttac ttaaatgcga ttcttgggca gtaatattaa ataatagcaa
     2221 taaagaaagt aaagcatata aaatattaga tgaacttaaa aggaatatgt acaaagttgt
     2281 tgctatagat gaagagaaga aacctattga aggtatagat gtgtatgaat gtttaaaaga
     2341 cgttccacac aatattgatg ttgtagctat tattgataaa caatctaaga tggatgtaat
     2401 tttagaagaa gtagagcttt tggatataca aaatatgtgg tttgaaaaag gaagctttag
     2461 tgaaatgatg attaaaaaga ctaaagattt aaaattaaac atagaatata atttaagttt
     2521 atatgatgag ttgactagat aaaattatgt actttaataa taaaaatata attagttagc
     2581 aaaacatatt atttcatagt atagattggt taatgaaaca ttaaattaca atatttgtta
     2641 aaaaattatg agttacatga tataatatat taaataggat actaaggagt tggtatatta
     2701 tgttaatagt aactacagaa aaagtagaag gcaaaaagat atcaaaagtt ttaggcttag
     2761 tgagaggaag tacaataaga gcaaaacatg ttggaaagga tataggagca agttttaaaa
     2821 atcttgttgg aggagaactt actggatata atgaaatgct tactgaagca agacaaattg
     2881 ccataggtag aatggttgaa gatgcagaag ctaaaggtgc aaacgcagta atagcattta
     2941 gattgtcttc agcatcagtt atgcaagggg cagcagaaat gcttgcttat ggaacagcag
     3001 ttgttttaga agatgataat agtattcttg aaaaataaaa tataaatagt taaaaagagg
     3061 catcttttaa aaattttatg gatgcctttt tttatttgaa aaaactaatt tcagaagaaa
     3121 ttttaattat tatgacaata aaattagggt gatattatat aaataagtaa aattatatta
     3181 tataatgtat ggtatagact ttaaaaattt tattggtaga gaaaaatatg gacaatgtta
     3241 taataattat agaaattaaa agtacttaca ttcattatat atgttacatg tataattagt
     3301 tttatattta atgcagtttt gaagtactat cttcattttg agaacgttgg aataataaaa
     3361 aatgtatgta ttataagtga tataaataaa aaataaatat aatatgttgt attgctgata
     3421 gaaaagggaa taaagtaaag taggttttat tgaaagagat ttttatttat aggacttaat
     3481 caatgtatag aggggggaga gcatatgttt aatgttgcaa ttataacact tagtgataaa
     3541 ggatatgaag gaaaaagaga agatataaca ggaaaaaaat taactgaatt tgttgaaaat
     3601 acaggagctt ataaagttac tgaatatgta cttataaaag atgataagga aatgttaaag
     3661 gaaaatatta taagactttg taatagtaat agaatagatt taattcttac aaatggaggt
     3721 actggttttt caaaaagaga tataactcca gaagcaacta aggaagtatt ggaaaaagaa
     3781 ataccaggtc tgagcgaata tatgagaatg aaatctacag aaattactaa aaaggctata
     3841 ctaagtaggg gtgtgagtgg aataagaaat aattctataa taataaattt acctggaagt
     3901 cctaaaggtg cagttgaaaa tttaagtttt ataattgatg ttttagatca tggcatagaa
     3961 attttaagag gacaagttac agaatgtgcc actaaaaaaa gtaaatagta tataatctag
     4021 atagataaaa aatagacaaa gaggtagata gagtatgatt gataagtatg gaagaaaaat
     4081 agactacctt cgtatttcac ttacagataa gtgtaattta aggtgtgtct attgtatgcc
     4141 accagatgta aaatttgata aaaattatat aaatgaaaat ctaagttttg aagattacaa
     4201 gttcattata aaggctatgg ctgaacaagg tataacaaaa gttagattta ctggaggaga
     4261 acctctttta tatcctaaat taaatgagct tataaaattt acaaaagaag aatgtggaat
     4321 aaataatata ggcatgacca ctaatgctat tgggctttct gatagaatac ttgagcttga
     4381 aaaatgtggc ttaaataaag ttaatataag tttagactct ttgaaggaat ataagtataa
     4441 atccataaca agaggaggaa acttaaaaga tgttttaaaa tcaattgaat cttgtttaaa
     4501 tttaggtata aaggtaaagt taaattgcgt tgctataagt gggtttaatg atgatgagct
     4561 taaagatttt atgtttttaa cagttaaatc accaattgat gtaagattta tagaacttat
     4621 gccattaggt gaggctaata gagtttataa gaaggggtat tttaatgtaa aagaaatgat
     4681 tgaaaaaata tatggtttat ataaagtcaa aaatgatgaa aagagtacag cagaatatta
     4741 tatgtttaaa ggagctaaag gaaggatagg aattataact ccattaagct gttcattttg
     4801 taacacttgt aatcgtatta gacttacttc tagtggtgca ataaaattat gtctacattc
     4861 aaaagaagaa atagatataa aaccattttt acataaacca ttgttattta gagaatctat
     4921 gaaagatata ataaaacaaa aaccagaaaa acatcattta atagaaaata aatgtagtga
     4981 tacaaatagg cgtatgtatg aaattggagg ataagtaatg ttaacacata taaatgaaaa
     5041 agggtatgcc aagatggtgg acataagtga aaaagatgat actaaaagaa cagctgtggc
     5101 tacagctaca attactctta gtaaggaagc tttagaaaaa gtaaaaaatg gtcagataaa
     5161 aaaaggagat gtattgtctg tggctcaagt tgcaggtata atgggagcta aaaatacatc
     5221 ttcaaacata ccaatgtgcc atcagattaa attagttgga tgtgatttag aatttgatat
     5281 agatgattct atgtctgcta ttaagatata tgcaacctgt aaatctcttg ggaaaactgg
     5341 agtagaaatg gaagctttaa atgcatgttc tttagcagca cttacaattt atgatatgtg
     5401 taaagcagtt gataaaaaaa tggttataag taatatccat cttgtggaga aaactggtgg
     5461 aaaatcagga gattttaagt tcgagtaaat taataatata ttgaaaattt ggaggaaata
     5521 tggctaaggt agtgtcaata aatataagtg agaaaaaggg tgtaattaaa gttcctgtac
     5581 aatgtgcaga gctaaaaata aatcatggga tagttggaga tgcacatgca ggaaactggc
     5641 atcgtcagat aagcttactt ggaaaagaaa gcatagataa aatgaaaatg aaaggctttg
     5701 accaattaaa atatggagat tttgctgaaa atataactac agaaggtata gaagtttttt
     5761 ccctgcctat tggtacaaag ctaagaatag ggcaatgtga agttgaagta actcaaatag
     5821 gaaaaaaatg tcacaatgga tgcgaaatta agaaattaac tggggattgt gtaatgccac
     5881 gagaaggaat ttttgtacag gttctgaaag aaggaattat aaatgtgaat gattcaatag
     5941 atgtaattta atgaagttag tattaaaata taattataag t
//
LOCUS       DAMKOJ010000141         5943 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.150, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000141 DAMKOJ010000000
VERSION     DAMKOJ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5943
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.150"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            152..892
                     /locus_tag="PC592_003415"
     CDS             152..892
                     /locus_tag="PC592_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDF4057342.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKDLN
                     IKYIFDYRSDQEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIDYKPKFKGIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YTSVEAYLYGEFNLNKEEIKKLRNQYLE"
     gene            904..2682
                     /locus_tag="PC592_003416"
     CDS             904..2682
                     /locus_tag="PC592_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4057343.1"
                     /translation="MSLNITARQVNIIKILLNSKDTISGLALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFEEINLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIREKKLLIKKLLLDILNENGLVLTDIEFKNVLNNILVMLS
                     RHKYNEKEFIENYVENYRRKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSDKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKVFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYELIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            2849..3766
                     /gene="pfkB"
                     /locus_tag="PC592_003417"
     CDS             2849..3766
                     /gene="pfkB"
                     /locus_tag="PC592_003417"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF4057344.1"
                     /translation="MIYTVTLNPSIDYIVKLNELKTGSTNRVNEEYVYPGGKGINVSR
                     ILKELGNDNISLGFISGFTGEYIIRTLEEKNLKTDFIKIKNGFSRINVKIKESEETEI
                     NGQGPNIDDEDIDILYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            3803..5722
                     /locus_tag="PC592_003418"
     CDS             3803..5722
                     /locus_tag="PC592_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4057345.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAIFAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSNSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIATKDNNTNKYPQVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YAINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         2440 a          555 c         1076 g         1872 t
ORIGIN      
        1 taggttaatt ttgtataaag atatactttt atattttaca attgctaacc aaatactaga
       61 aaatatttta aataaagaac ttaaaattgt gataaaatta atttattgat atttaaaaaa
      121 gtatataata tggtttttaa gaggtgttaa gatgaaaaat tttagagatt taggtggtaa
      181 caaaactgag gatggtagga ctgtaaagaa gggattgttt tataggtctg caaaattatc
      241 aaatttaagt gaaaatgata taaagatttt aaaagattta aatattaaat atatatttga
      301 ttatagaagt gaccaagaag ctcgtaaaca tccatcaaca ataatatcaa atataaaaaa
      361 tataagaata ccagcaatga gagagttaga agaatcagga ggaagttttg gttctattga
      421 agatatgatt gatggattgt ttgaaaaaga tggtgcattt aatatgttaa ataatagcta
      481 ctataatttg cctataaata atccttcata taaaaaacta gtagaactta taagagacta
      541 ttctaattta ccaatattaa atcattgtac agctggtaag gatagaactg gtgtagggag
      601 cgctataatt cttatgattt taggggtatc aagagagaat ataatgaaag attatctaaa
      661 aagtaatgat tttgcagata aagagataga aagatttata gattataaac ctaaatttaa
      721 ggggattcca aaagaaaatt taaaatatat atttggtgta aatgaagagt atatgaaaac
      781 tgcatttaga agaatagatg aagaatacac tagtgtagaa gcatatttat atggagaatt
      841 taatttaaat aaagaagaaa taaaaaaatt aagaaatcaa tatttagagt aaaaggtgat
      901 tttatgagtt taaatataac agcaagacaa gtaaatataa taaaaatatt gttaaattca
      961 aaagatacaa ttagtggtct tgccttaagt caagagatag gatgttcttc gaaaactata
     1021 caaaatgaaa taaaggatat taataaacaa cttagaaatg gtaaaatctt gtcaataaga
     1081 ggagttggtt ataaactaga aggaagtttt gaggagataa atctaaatag taatctctat
     1141 gatgatgtag atagagtaga atatataatt agaaaaatat taaccttaag taatgaagaa
     1201 aaaaatacta taaaacttga agatttagcc gattctatgt atgtaagtgt ttcgacagta
     1261 aaaaatgatt taaaagaagt aaaaagaata ttggaaaagt attcaatatc agttaaatct
     1321 aagcataaac aaggtatatg tgttttggag agtgaggata agatattaaa ctgtatagtt
     1381 gacttaagca ataagagaga taatcaattg agtttaaatg attttttaaa tgatgacata
     1441 agggaaaaaa aattactaat aaaaaaatta ctattagaca tattaaatga aaatggattg
     1501 gtattaactg atatagaatt taaaaacgtg ttaaataata tattagttat gttaagtaga
     1561 cataagtata atgaaaaaga atttatagag aattatgtag aaaattatag gcgcaaaaga
     1621 agctcaattt tagaaaatga acaaaacaaa gaaattataa taaattcaat aaaaacattt
     1681 tgtaaaaatt taaaattagc tacatcaata gatataagta atgataaggt atttgaagaa
     1741 tttttatata agcatattag tagtttatgt aaaaaaataa agctaggtat aaatcaatct
     1801 cctataatgg ctcaagatat aaaaataaaa tatccatttg cttttgaact agctaatata
     1861 gctaaaaaga caatagaaaa agatttgaag atagaaatta atgaagatga agttgcaaac
     1921 atagctctac atataggagg agcagttgaa agagcatctt ataataataa agataaggtt
     1981 ttcaaaacta taatagtctg tacttcaggt ataggtacat caatgttaat aaaagctaaa
     2041 ttagagaata tatttaagga aaaattagaa atattaaaga ttattccttc atacttagtt
     2101 gaatatataa aagttataga tgttgatttt gtaatatcta ctgttcctat tgaagtagga
     2161 gatgtaccag taataaatat atctccgatt ttaagtgata aagaaattag attaattgaa
     2221 aaatatatag aaacaggaaa tatatatcta gatttagata taaaaagcct gtttgatagt
     2281 gaattatttt ttactgattt ggtgtttaaa aggaaagaag aagttataga ttttatggca
     2341 agtaaacttg tacaaaaggg atatatagat gaggatatga aaaaatctta ctttgagaga
     2401 gaaaaaatag caacaacaga aatagggaat atggtaacca taccacatgg tgctattgga
     2461 aaagtttttg ataataaaat agcaattggt atattaaaga aacctatttc ttgggaaata
     2521 tcagatgttc gtttaataat aatgttagct cttgataaag acaaaatatt agattatgaa
     2581 ttaatctttt caaaaatata taaaagagta gattccatag caaaagttat aagtatatgc
     2641 gaaaatagca gttttgaaaa atttgtaaat ttatttaatt agatgggtgg tattgtatat
     2701 acatctgtaa atttggataa tataaaacta aataaaataa aaacgataaa tttctctttt
     2761 aattaagaga aattttttga ctttcaagga tattaatata aagttaagat ataaacataa
     2821 ggtaaataaa taaaaaagag gtggcaatat gatttataca gtgacattaa atccatcaat
     2881 agattatata gttaagctaa atgaactaaa gacaggaagt acaaatcgtg taaatgaaga
     2941 atacgtttat ccaggaggaa aaggtataaa tgtatctcgt atacttaaag aacttggaaa
     3001 tgataatata tctttaggtt ttataagtgg ttttactgga gaatatataa taagaacatt
     3061 ggaagaaaaa aatttgaaga cagattttat aaagataaaa aatggttttt caagaataaa
     3121 tgtaaaaata aaagagtcag aggaaactga gattaatgga caaggtccaa atatagatga
     3181 tgaagatatt gatattttat acaaaaaact tgataagcta aatcaagatg atattttaat
     3241 attggcagga agtataccat ctactttaga tgaaaaacta tacgaaaata taatggctag
     3301 attagaaaaa aagaatataa aagttgtagt agatgcaact aaaaatcttc ttcttaatgt
     3361 tttaaaatat aaaccttttc taattaagcc taataacgac gaattagaag aactatttgg
     3421 tgttaaatta aattcaattg aagacatggt aaaatatgct agaaggttaa aggaaatggg
     3481 ggctataaat gtcttggtat caatgggtaa agatggagca ttgttgatta cagaggaaga
     3541 tgaagtgctt ataagtgatg ttcctaaagg aaaagtaaaa aattctgtag gagcaggtga
     3601 ttcaatggta gcaggattta tatctgggta tttgaatact ggtaaatatg attatgccct
     3661 taaattggga gcagcttcag gtagcgcaac tgccttttca tatgacttag ccaaaagaga
     3721 atacattgat aaattggtaa atgaaatatc tgtaaagcag ttttaaaata ttaaaaaata
     3781 tatagaaagg taattaatat ttatgaaaat tatagattta ttagatgaaa agtcaattaa
     3841 gttaaattta aattcaaaaa ccaaatcaga agcaatagaa gaattagtag atttggtcgc
     3901 aaatagtgga aatttaaatg ataaagaaaa ctacaaaaaa gcaatttttg ctcgtgaaga
     3961 aatgagtaca acaggaattg gagaaggtgt agccatacct catgctaaaa attcttcagt
     4021 tactaaagct tgtatagcag cagcagtgtc aaaagaaggt atagattatg aatcgtttga
     4081 cggaagttta tcaaatctat tttttatgat agctgcacca gacggagcta acaatactca
     4141 tcttgaagta ttatcaagat tatctacaat acttatggat gaagacttta gaaataaact
     4201 tataaactca aactctgaaa aagaatttaa ggaaataata gataaaaagg aacgagaaaa
     4261 attcagtgaa gaatatcaag atgagaaagt tgctgaaaaa aatataatag ctactaaaga
     4321 taataatact aataagtatc ctcaggtatt agcagtaaca gcatgtccaa ctggaatagc
     4381 gcatacattt atggcagcag aaagtttaaa taaaatggcc gaaaataaag gtgtatcaat
     4441 aaaagtagaa actaatggtt cagcaggtgt taaaaataag cttacaaaag atgaaataga
     4501 gaatgcaaca tgtataatag tagcagcaga taaaaatgtt gagatggcta gatttaatgg
     4561 caaaaaagtc ataaaaacta aggtggctga tggcatacac aaagcggaag agcttataga
     4621 caaggctgta aatggagatg ctccaattta ccatggagga gatggaagtc acaacgaatc
     4681 aaatgaagaa agtgaaagtg gatttagaaa agtatacaaa cacttaatga atggtgtatc
     4741 taatatgtta ccatttgtta ttggtggagg tatacttata gcgatagcct ttttacttga
     4801 tgattatgct attaaccctt caaactttgg ttcaaataca ccgatagcag cattttttaa
     4861 aggaatagga gataaagctt ttggatttat gttacccgta cttgctggat atatagcata
     4921 ctctatatct gatagaccag cgtttgttgt aggatttgta ggaggtgctc tagcaggtga
     4981 tggtggttca ggctttttag gtgcactact tgcaggtttt atagcaggtt atttagtaga
     5041 agggcttaag aaaatattta gtgtactacc agcttcattg gaaggaataa aaccagtatt
     5101 gttataccct ttacttggaa cacttttgat gggaattata atgacatttt tagtaatacc
     5161 tccagttaca gcaattaata atgcaatggt tggattttta aatggtttag gtggaacttc
     5221 aaaaatagtt ttaggattag tattaggtgg aatgatggct gtggatatgg gtggacctgt
     5281 aaataaagca gcatatgtat ttggagttgc atcacttgaa tcagggcagt ttgaaataat
     5341 ggcagcagta atggctggtg gtatggttcc gccacttgct atagctcttg caactacatt
     5401 ttttaagaat agatttacta aagaagaaag agattctggt aaagttaatt atgtaatggg
     5461 attatcattt gttactgaag gagctatacc ttttgcagct ggagacccac ttcatgttat
     5521 accagcttgt gttggaggtt cagcagtggc aggagcactt agtatgttgt tcaacgcagc
     5581 tcttcgtgca cctcatggag gagtatttgt tataccagtg gttacccatc catttgcata
     5641 tatattagct atagctgtag gtgctttggt tggaatgatg cttttagcat tacttaaaaa
     5701 accattaaat caagaagtat agcaattaaa ggatattcaa gaacttaaaa tatgatgttt
     5761 tataaaaatt aatatattgc tgaattattt taaaataagg attttatgag gctgttatat
     5821 aacgatttgt aattgttatc ttgacagtct tttattttta tataagtaaa ataagtgtgt
     5881 tttgctttat ttgtatttaa attgttttta agttagaata taaagaaaat tatatattat
     5941 ttt
//
LOCUS       DAMKOJ010000142         5917 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000142 DAMKOJ010000000
VERSION     DAMKOJ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.151"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(173..1135)
                     /locus_tag="PC592_003419"
     CDS             complement(173..1135)
                     /locus_tag="PC592_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDF4057346.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIVDEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQRITKERNAFRADQFNLEA
                     CNHAHENYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKALKGHKSSIKCYVVEPKTA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQITDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSTERGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            1326..1877
                     /locus_tag="PC592_003420"
     CDS             1326..1877
                     /locus_tag="PC592_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057347.1"
                     /translation="MSINTIIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SMHTYHNQGEKTLKAVIINYYPV"
     gene            complement(2412..2699)
                     /locus_tag="PC592_003421"
     CDS             complement(2412..2699)
                     /locus_tag="PC592_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057348.1"
                     /translation="MKKFLYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFMTIKIFIFLSLPLCFNILFDYLTS"
     repeat_region   3270..4418
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3270..3298
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
     gene            5064..5888
                     /locus_tag="PC592_003422"
                     /pseudo
     CDS             5064..5888
                     /locus_tag="PC592_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
BASE COUNT         2197 a          896 c          630 g         2194 t
ORIGIN      
        1 attcattttt attttatgac taagcataat tatctatata aatttatgct tatagtcatg
       61 atactacatg tttattaaaa aaaaaagtat ctcattaatt tttaaaaatc attttgagat
      121 actttttaca atttaaatcc atatatttaa cttaagaaac actgtatcat tattataatt
      181 cttcatataa atcagtactc aagtatttca gaccactatc attaagagtc aaaactatat
      241 ttttacctct ttcagtactc tttaataact taattgctgc gcatacattt gctccagaag
      301 aaaaacctgc aaatacacct tctaatttag ctaattttct tgctacatca gttgcctcct
      361 catctgtgat ttggatataa ccatcaataa gtttcttgtc tactagtggc aagtccatag
      421 aatatcctcc accttggatt ttatgacctt ggtcagttat ttctttacct gagtaaattg
      481 ctgctgtttt aggttcaact acatagcatt ttatagaaga tttatgtcct ttaagcgctt
      541 ttgagcaacc agcaaaagta ctaccacttc caagaaaatc tacaaataca tcaatatttc
      601 catccaattg ttcccacatt tcttctgctg tataattttc atgtgcatga ttacaagctt
      661 ctagattgaa ttggtctgct ctaaatgcat ttctttcttt tgttattctt tgagcttcaa
      721 tttctacaag cgctaaatct tcaccagata cttgtccatg aactgagtta ggcatttggt
      781 ctacaagaac tacttctgca cctaaagctt tcatcattct tgctctttcc atagaatttc
      841 cttttgacat acatgctata aatttataac ctttacatgc acaagctatt gctaaccctg
      901 ttccagtatt accacttgtt aattccacaa ctgcttgacc tggaactaat aagcctgcgt
      961 tttctgcttc ggtaatcatt tgtaatgcta cacggtcctt tttgctaaat cccggattta
     1021 agtattccat ctttgcataa atattacctt gaactccaaa ttcatctact attttggata
     1081 aatgtaacat atgagtattg cctatagcct ctgtaacatt attaagtaca cgcattacaa
     1141 ttccccctta atctctcaac tatcatccgt tgaaaaacaa ttctttatgc agtataattt
     1201 atattacgga tgtacagtgt atttaacgtt cattatatta tacatttgta aattataaat
     1261 aacgttaaat aaattatata ttcgtaaatt atatttgtca ataatttaca ttttaaggag
     1321 ctaatatgag tattaatact attattgcta aaaacctaaa tagattacgt aatgaacgta
     1381 acttaagtct aggtcaactt gccgaattgt ctggcgtaag taaagtaatg ctttcgcaga
     1441 ttgaaaaggg agactcaaac cccacagtaa acacaatttg gaaaattgca agtggactaa
     1501 atgttccata tactgcaata ctggaacaac cccaaaatga aacttttatt gtatcaaaaa
     1561 ctgatataga tgtacaagtt tcagagaata aagattatcg tctttattgt tattatccta
     1621 atacaccaac tagaaacttc gaattatttc aaatggaatt agaagaaggt catagctata
     1681 catctgttgg tcattctgaa aaatcacagg aatatattat gattatagaa ggtcaattaa
     1741 aattagaagt aaatgactct atttatcaac ttagagaaaa tgactctatt tgtttttcag
     1801 ccgaatcaat gcatacatat cataatcaag gagaaaaaac attaaaggca gtaataataa
     1861 attattatcc agtttagcca tgtcatttaa tgatagaata attattttct atacaaaaag
     1921 ataaatcctt tgattaagat ttatcttttt cattttattt ttctttataa attcattata
     1981 tatctttaca cttttatcaa ttatgttata ataagcttat ataaaagttt tatatttttg
     2041 acaaatggag tacaaaatac tcctttttct tttttactat tgtgataatt atttagttag
     2101 tattaaaata ttatcactta aaacaaatac aaaacgtctc ttatatgtac atttttcatt
     2161 gttgtaataa tgatttgtgt atgtatttct cacaatcgga gtgcttatgc actcttttta
     2221 aataccttta ttaccacaat ctaaaagcta ttttattatc cattttaatt tatttttaag
     2281 taatcaaata aattatttta tattttttct tcatttatat gaaacttttt tatcactata
     2341 tgcactttat atttaatata aataacacat aagcttgctt ttatcataac actccaatat
     2401 ttaaatataa tttaagaagt taaatagtcg aatagtatat taaagcataa tggtaatgac
     2461 aaaaatataa aaatctttat agtcataaac tttatcttat catttttatc ttctccatta
     2521 aaataattat cttgataaaa tgtagctcta ttttgataac ctgtttttaa aactccattt
     2581 tgaattaata gcagtataaa aaagattgct aataaaataa agttataatt tttttctttt
     2641 aatctaaaat tcgctataat aacaatgaaa ctatataaag catataaaaa ttttttcata
     2701 aaaaacacct aaattctata tttgtatttt atattgagcc aaatctaatt tctgtatact
     2761 tattaagtgt agttctaatt tatattgtag ttggattaaa tatttcttaa tttttatttt
     2821 caattatttt tataatgttt atacctctat caatattaaa ttttgatatt tgtgttgttt
     2881 aacattgtat tactattaaa atctttttca acaaatacaa atggtatata tactttaata
     2941 ttatcaatac tgatagtaca agtagtacaa accctttaag tttataagag catctcctta
     3001 tatctaaatt atagtatgaa tattcacaaa tttcaatcta tttataaggt aattattttt
     3061 atatctagta tcttgtcatt aagttttatt ctatatattt ataaactttt caatactttt
     3121 tataattatt ctacttttat attttaatca ataagactaa agtcaatgtt atctggtaat
     3181 tacttactac aaatgataaa aaataattat attttaaagg agaaaatgct atataaatta
     3241 ttggagtatt ttacctatac ttgttgcaaa tttacatacc acatagttaa tataaaacat
     3301 tcgcaagttc ttaatcaaaa acccaatttt ctttatttac ataccacata gttaatataa
     3361 aacgctagtt gtacttaacc aatagccaaa ttgttgactt catttacata ccacatagtt
     3421 aatataaaac tattattatt tacacattta ctttcaaaac ttcttttatt tacataccac
     3481 atagttaata taaaactatc ctaagaattc tctcttagca tttggacatc ttaatttaca
     3541 taccacatag ttaatataaa acactcctgt agtattttca aaagttattg cgctaagcaa
     3601 atttacatac cacatagtta atataaaaca agaacgtgcg cttattcttg gatatcaata
     3661 taaagaattt acataccaca tagttaatat aaaacccatg ttcatttcgc ctttaaattc
     3721 aactttctca taatttacat accacatagt taatataaaa caagaaggtg aaataatatt
     3781 ctatgaaggg caattaaaat ttacatacca catagttaat ataaaacctt gatgtttagc
     3841 tttttgaaat aattcaagtt ttaaatttac ataccacata gttaatataa aacttttaaa
     3901 taacccccct ccccttctga ttttttcgtg atttacatac cacatagtta atataaaacc
     3961 gcccttttcg ctattatttt ttttataacc cttcaattta cataccacat agttaatata
     4021 aaactgaaaa attaaaagaa ttaatagata agcaattaat aatttacata ccacatagtt
     4081 aatataaaac cttctctgaa aatcgtatat tcttttttaa aagagttatt tacataccac
     4141 atagttaata taaaacgaac taacctcgtt tcctgtgtta ataaactatg atatttacat
     4201 accacatagt taatataaaa ccaggacaaa atagattatt tgactggtta agaaataaat
     4261 ttacatacca catagttaat ataaaacagt ttatttgggg attagataaa aataaggtag
     4321 catcatttac ataccacata gttaatataa aacaatctgt ttttcttctt cttctgcatt
     4381 atctacaaga tttacatacc acatagttaa tataaaaccc caaaataaac taagtatttt
     4441 cagtacttac acacatacaa ctttcttaaa tttgcagtga accatgagta gtgcaattga
     4501 taacatttat catacaccct caacgcctta cattgcaact gttaaaccct actttatcaa
     4561 aaatatcgct cactgcaaaa tttatatatt tttattatat cataaaattt aacctataaa
     4621 attaaaatgg agtaatttat caatttaaga atatctgcta gtgcttacta cattggatat
     4681 tctaataagt cttcttctaa ctggatttaa tataaaaatt ctctctaaaa aattaggtca
     4741 tactgatata aaaataacta tgaatagata ttctcatatt ttagataata tgcataaaaa
     4801 gcttctaaaa atataatcaa ggctctcttt aaataacatt cagttttata tcagtaaaat
     4861 atcagtaatc tcatattttt cttaaatgtc acttagatgt tagttatata ataatagtaa
     4921 acaactgtat ttcactaata tttgctatta tccaatagta tttatagttt agatttgata
     4981 taatacatgt ggtaaaattt tgatttgtaa cccaaaatat aacctacata tattaaaata
     5041 aatttaaaac taaggagacc tatatgttaa aagtactaaa aggaaatata attttcacaa
     5101 aaacttcaga aactttcaca gtatttgaaa atagctatat tatactagaa aaaggcaaag
     5161 taaaagaaat atttaaagaa atacctaagg aatacaaaaa tctagaaata atagattaca
     5221 ctgataaact tataatacct ggtatgaatg acctccatgc ccatgcctct caatttaaaa
     5281 atcttggaat ggctatggat aaagagcttt taccatggct tgaaacttat acatttccag
     5341 aagaatcaaa ttataaagat atcgaatatg caacgaaaat gtataaaaaa tttgtaaaag
     5401 aactttggaa atctggaact acaagaatag cagtgtttgc aacagtgcat aaagaagcct
     5461 ctatgaaact tatggatata ttcaaagaag ttggtcttgg agcatacgtt ggtaaagtaa
     5521 atatgaatat gaattgccct aatactttgt tagaaaacac tcatgattct attgctgata
     5581 cagaagaaat tataaataag tatagtgata cagattctat tgtaaaacca atagtaacac
     5641 ctagatttat acccagctgt acaagtgaac ttttaaaagg tttaggagat ttatgtttaa
     5701 aatataatac tcctatgcaa tcacacttat ctgaaaatta tgatgagatt gaatgggtta
     5761 gaaatctaga acctgaatct aaattctatg gagatgcata taatagatat aatttatttg
     5821 gtcaaactcc tactctaatg gctcattgtg ttcattgttc tcaggaagaa atagatttga
     5881 ttaaaaaata gctacgcaca cttgtgactt tagtcat
//
LOCUS       DAMKOJ010000143         5904 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000143 DAMKOJ010000000
VERSION     DAMKOJ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5904
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.152"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            130..1494
                     /locus_tag="PC592_003423"
     CDS             130..1494
                     /locus_tag="PC592_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDF4057349.1"
                     /translation="MDIKELVKIQRKYCNTGKTRDISFRIEQLKKLKSVVSQNEEKIL
                     LALKRDLDKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSIVKDIIENAFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIVMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDKKNELIEKIKYYTNKYFGDNPS
                     ANEQFPKIINQRHFSRILSLIDKDKVIYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKILEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKIL
                     KKIM"
     gene            1633..2799
                     /locus_tag="PC592_003424"
     CDS             1633..2799
                     /locus_tag="PC592_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF4057350.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAMF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGILLTYATAMLIL
                     YLFMYFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIVGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVLFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVEGKLDKKGLPTDTSDYM"
     gene            2916..3698
                     /locus_tag="PC592_003425"
     CDS             2916..3698
                     /locus_tag="PC592_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDF4057351.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQTSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMVYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYAESLHVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3817..4470)
                     /locus_tag="PC592_003426"
     CDS             complement(3817..4470)
                     /locus_tag="PC592_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4057352.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4494..5858)
                     /locus_tag="PC592_003427"
     CDS             complement(4494..5858)
                     /locus_tag="PC592_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF4057353.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSIFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLSAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKDATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         2211 a          744 c          913 g         2036 t
ORIGIN      
        1 ctttttttat tggaagattt atgttatatt gagataaatt tattatgata caaaaaataa
       61 tgttaggata aatttaaatc tttttctaaa aatgtataag tgtaattctt aaagaaagga
      121 tttttaacaa tggatataaa agagttagtt aaaatacaaa gaaaatattg taatacaggt
      181 aaaacaagag atatatcgtt tcgtatagaa cagttgaaga aacttaagtc agttgtatca
      241 caaaatgaag aaaaaatact tttagcgcta aagagagatt tagataaatc ggattttgaa
      301 ggttttatga cagaggtggg catgttttat agtgaattaa attttgctat aaagaatata
      361 agaaaatgga gcaaaataaa aagagttaaa tcaagtatgg ttaattttcc atctatatct
      421 aaagttgttc cacaacctta tggtgttact ctcataatgt cgccttggaa ttatccattc
      481 caattagcac ttataccatt agtttggtca ttagcagcag gaaattgtgt tatactaaag
      541 ccttctgaat attctgtatc aacatctagt atagttaaag atataattga aaatgctttt
      601 tcaaaagaat atgttgcagt tgttcaagga agtcaagaag aaagtgaaaa attactatta
      661 gaaagatttg attatatatt ttttacagga agcactaatg ttggcaaaat agtcatgaaa
      721 tcagcatcag agcatttgac tcctatcact ttagaacttg gagggaaaag cccttgtatc
      781 attttaaaag atgccaatat agaccttact gctaaaagac ttacttgggg aaaactaata
      841 aatgcaggac aaacttgtgt ggctccagat tatgttttag tgcatgaaga taaaaaaaat
      901 gagttaatag agaaaataaa atattatact aataagtatt ttggagataa tccgtctgct
      961 aatgagcaat ttcctaaaat cataaatcag agacatttta gtcgtatatt atctcttatt
     1021 gataaggata aggtaatcta tggtggaaat tataataagg agacattaaa gatagagcca
     1081 actatagtag acaatgttaa ttgggatgat aatataatga aggaagaaat atttgggcct
     1141 atatttccaa ttttaacata taaagatttg gatgaagtaa tacaaaaaat tatacaaatg
     1201 ccaaatccat tagcccttta tatttttaca aaaaataagt acctagaaaa taaaatttta
     1261 gaaatgattc cagcgggtgg atgttgtatc aatgacacag ttactcatat agctacgaat
     1321 tacttacctt ttggtggtat tggtgaaagt ggtatgggat catatcatgg aaaagctgga
     1381 ttcgatacat ttactcatta taagagtgtg ttaaaaaaat taaatttgga tgttcctatt
     1441 agatatgctc catatgataa taaattaatt aagattctta aaaagataat gtaggttata
     1501 ttgtagaaaa ataaatataa ataaaattga atatttgtat tctgaatata ttttattttt
     1561 aatttggcat atttgttata aaagtggtga ttttatgata aaatttaatt atatagaaat
     1621 aaggaggaaa aaatgaaaat taattggaat acaaaataca caacaatagc aatttatacc
     1681 tttataatag cggctagtag tattatattt tatctagtat catcacaaat tgatgtattt
     1741 tctaataatt tagacgctat gtttacaaca ttacaacctt ttataatagg atttgctatt
     1801 gcatatcttc ttaattttat tttaaagttt tatgaagaca gaatttttat aaaaagtgag
     1861 aaattgaaaa aactaaaaca aagttcaaaa agaggtttgg gtattttatt aacatatgca
     1921 acagccatgt tgatacttta cttatttatg tatttcgtat tgccacaagt aattgagagt
     1981 attgttggac tagcaaatga tatacctatg tatgtaaaca atgcaactaa gcttattgat
     2041 aaattaatga ctgatttaaa tcttgatgag caatacttta atttggcagt tgataaatgg
     2101 aatgagtttg ttacatatat tataaagttt gtaacagatt taatcccaat attaggaagt
     2161 atgttaaaga atgtagcctc tagtatatgg aatattgtat taggattaat tgtttcagta
     2221 tacctattaa ttgataaaga aaaattctat ggattaagta aaaaaataac ttatgcagtg
     2281 tttacagaaa aacaagctgc tagaatttta gaattaactc acagaagtaa ctatacattt
     2341 ggaagattct taggtgggaa aatattagat tcattcattg taggtattct aacatttgta
     2401 atacttacat tagttaaaat gccatataca ttactaatat cagttataat tggtattaca
     2461 aatattattc ctttctttgg acctttattt ggagcaatac catctacact aatagtattg
     2521 tttgtatctc ctataaaagc tttctggtta ttgttaatta tattaataat tcaacagata
     2581 gatggaaata ttatagggcc taaaatactt ggagattcaa ttgggatatc tgcattttgg
     2641 attttgttct ccttattggt tgcaggaaaa ttattaggtt ttattggaat ggttatagga
     2701 gttccaatgt ttgcagtaat ttattctata attaaggata ttgttgaagg taaattagac
     2761 aaaaagggat taccgacaga tacttccgat tatatgtaac taaaaaatgt tatgtataat
     2821 taaaaatata taaattaagt aatatttaaa gcactgagaa agtcaaactc ttggtgcttt
     2881 ttagatataa aattattata gaagaggtgt tttttgtggc atttatagaa tgtaaattta
     2941 aatctaagta tactggagga gaaactgata taattgtaat tttacctgta gcaaatggaa
     3001 aagaactttt tagtggtaaa gagatatatg attttgaagg taaatttaaa acattatact
     3061 tatttcatgg tttagaagat gaccaaacct catggattag atatactaat gtagagcatt
     3121 atgctaaaaa taaaaatata gctctagtga taccaagagt agaaactagt ttttacacag
     3181 atatggtata tggacaccaa tattttactt ttgtaagtga ggaattacct aaatttgtta
     3241 gagctatatt tcctttatca gataaaaggg aggacaactt tgtagctggc atgtctatgg
     3301 gaggatatgg agctttaaag ttagcacttt caaaaccaaa agagttttcg gcagttgcaa
     3361 gtttttctgg ttcacctgat atgattcatg agttagaaaa tcaacaaata gaaaccaatg
     3421 cagatattct atttcatgat tttggtagac cagaagatgc tagaaatagt gagaatgatt
     3481 tactttacat acttaagaac cttaaagaga gaaatgaaga cattcctaaa atttatcaat
     3541 tttgtggaga tagagatttt ttatataaaa ataatcagat gtttaaaaaa tatgcagagt
     3601 ctttacatgt agatgttgaa tatgaagagt gtgtaggagg gcatgaatgg cgtctttgga
     3661 atttatggat aaagaaattt atagatataa ttgggtagta tgcttatggt attaacagag
     3721 atactataaa atatctttaa atatgataaa gactgaaatc ataaaatcaa atcatgattt
     3781 taaaatttca gtctctaaga atttaataaa attttattaa gttcttacac gagttattat
     3841 tggagtaaaa ttgtcaacta tatctatata gtatttactc aattcttcta aaatctcttc
     3901 gcataaatca gtactatgac caagattaat aagaaactgt tttgtaaaat gctttattac
     3961 agcttgagaa gatatatcat acttgtgtga agtataaact ctaattattt caggtttcat
     4021 agcaagtata ccaatacaag aaagtattaa ctcatcatgt tctatagatt ctttatcatt
     4081 aacatatctt ttcatgacca tttcggttac acttctttga tagcttaaaa tggcttcttc
     4141 ataagctata tccaaataaa aatttctata tgcttcattt tttagaagga aacaaaggtc
     4201 agcattcata gcaagaaaga acatcatcat agtaccttct tcatggtagt tatagattaa
     4261 agattgcatt tcatttctta tatcttcata tattatagct cctatttcgc ttttacttga
     4321 aaagtaatag cttattagac ctaaatttat attagctctt tctgcaattt gcctagtcgt
     4381 tgtcttatga taaccttgct caaaaaataa ttctctagca gcacttataa tactagcttt
     4441 tgtttctttg cctttttctg attttgacat atttactgtg tatacctctc ttttcaatct
     4501 ttttttgaaa atttgctaac tataaatatt gtaatagaac cacctattat aggaaccaaa
     4561 attctatcaa atacagtaag aataccaatc atatttaata atgccagtat aacacttact
     4621 ataacagcat atatagctcc tttttttgta gcatctttcc agcaaagacc aattacaaat
     4681 ggtgcaaata ttacacctgt acatagtgga gctggccaaa acaataattc taataaacta
     4741 tcaaatttaa gtgctatgat tgcacctatt atagctgtta gagctgatgc aatttgagaa
     4801 tactttagag tattttttaa atcattaaat tctatattag ggtgtaacaa tttgttataa
     4861 atatctcttg atatgatagc actcattgag gtcattaatg aatcggcagt agacattatg
     4921 gcagccaata tagcagataa gaacaataca gagattaaag gtggcaaagt agtcgatatc
     4981 atttgaggta aaacctgaac agatgatatg tttggaaata aactaccacc aatagctcca
     5041 attattccta tagggaaagc aagaaataat agtataaatc ctgcaattac actactttta
     5101 actgcatttt tagcattatc agcacattga tatcttaaaa aactttcata agaaaatatt
     5161 gagcctaaaa ctaatggtaa aactgtatac ataaaatcac taatcgattt atttcctgga
     5221 aagaatggtt cttttaccat tgattgtaac ataagtaaag ggttgtcgcc aactaatttt
     5281 aagcttatat aagctactat tggcaaaaac actatacaaa tagcaagttg aataaatgct
     5341 gatactgcaa ctccccacat tcctgatgta taagtatata taatgatgac tataactcct
     5401 ataattacag ctatatcata aggaatgcca aatgcagtag acacagaacc aaaagagatt
     5461 aattgactac ccataatggc tagtatagat attggtgtta caagactttg ataagctctt
     5521 aaaaatatac tatgaccata tctagtttca atataatcag caggtgttat atcgcaagat
     5581 aagcttctta attttcctgc aaaaaatgcg tttataaagc aggctaaagc tgcacctata
     5641 gtagaataca ttccaaccca aagccctctt tcagctcccc attgaactcc accaactaag
     5701 caccctcctc caaaagatgt agcagcaatg gttgcagcta gtataggtaa aggaagattt
     5761 ctacctgcaa ttaggaaatc ggatgctgtt ttaacttttt ttgaaaaata aaaaccaatc
     5821 catatgtata ttgcacacgt aacaattaaa agtaacatag tctcttctcc tttataaaat
     5881 attttaataa aatatatttt aaat
//
LOCUS       DAMKOJ010000144         5654 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000144 DAMKOJ010000000
VERSION     DAMKOJ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.153"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            263..1114
                     /locus_tag="PC592_003428"
     CDS             263..1114
                     /locus_tag="PC592_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF4057354.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDISIAISYSGESKEVIKSIENAKLKGCKVICMTKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNIDNA"
     gene            1725..2759
                     /locus_tag="PC592_003429"
     CDS             1725..2759
                     /locus_tag="PC592_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF4057355.1"
                     /translation="MKKIRKLATKLLITTMVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDVIYKSLSHPLPFDKTAYPTVGAVAQTQKKPAPPGKHTMLPHQEGA
                     KVVGKFGDIKDKHVMYEGVRCVVINSSVNTVTFMGSESNLDPSELTIAVIGFMNTPYG
                     MFALAPESKPVEYPFEYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIEITDEKANTG
                     LGQIMYIRYE"
     gene            complement(2875..3894)
                     /locus_tag="PC592_003430"
     CDS             complement(2875..3894)
                     /locus_tag="PC592_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057356.1"
                     /translation="MLKLSLLYLFKGGLHLNNINSLKVIKLSLGCSLAIFIAWLLKLE
                     YSMVAGVIVLLTVKDTKRETLKGSIGKVYGFLLCTIFSYLCFNILGYNLISFSVFIFI
                     IIPLCFLLNIQDVIAMCVVIASHYFLQGETSIKWILNEAGIFAVGTGIGVLINMYIPT
                     NIHKIHEVQKKLQEEVSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNI
                     NNTLLSDTRFFLEHMDIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGHTEFE
                     AETGNLLLEELKRLMLSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKNAQMLRD
                     NNFYK"
     gene            4321..5202
                     /locus_tag="PC592_003431"
     CDS             4321..5202
                     /locus_tag="PC592_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HDF4057357.1"
                     /translation="MKITEGYMPFEGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIKELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSARLWEKEQKRRISYMSESDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGARDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIEVLTEWLDAND"
BASE COUNT         2190 a          700 c          950 g         1814 t
ORIGIN      
        1 gcaagtataa atatattaaa agaaggatta agactaataa caattcaaaa taaataactt
       61 atgtaagaac cgtaggaact acggggatag cctgtggaga attagtaaga catattttag
      121 tatgcaaaat tctatgaagc aggaaccctg tgactttagt catgggaggt tcagatggtg
      181 agaccagtgt tgactccaga tttaggagca tgtttacttg ctaagaagaa atattatagt
      241 aaataggtag aggtggtaga gtatgagttg cattttaaaa ttaaaacaga tatatgaaga
      301 tttaacagaa gtagataaaa aaatagctga ttacatactt aataatacag aggctataag
      361 taagctttct gtatcagaat tggcgtcaaa ctcaaaaacg agtacagcaa gtatagttag
      421 gttttctaga aaaatgggat attcgggttt tggagattta aaaattgaga tagctaaaga
      481 tttgatgggc aaagaaaatg aatacacata tgtagatgaa aactatgatt gtaatataga
      541 tagtgttata aacaaaatta caaacaaaaa catagagact atcaaccaaa caaggttgtt
      601 gaatgaaaaa gatataataa aagaagcagt tgaacagata ataaaggcta aaaatgtata
      661 catatttgga gtaggtggtt cggctttagt tgcactagat ttacagatga aacttttaag
      721 gataaataaa caggcattta cctctttaga tagtcataca caacttatgg tatcttcaaa
      781 tgtagataaa gaagatatat ctatagcaat atcttactct ggagaatcaa aagaagtaat
      841 aaagtctata gaaaatgcaa aattaaaagg atgtaaggtc atttgtatga ctaaatatag
      901 tgacaatcat cttagtaaga ttagtgattt aaagctagta gtaccaaata tagaaaaaag
      961 gcttagagaa ggagctattt cttcaagaat agcaatgctt acattgatag atataatata
     1021 tatttctata attcaagaaa acttaaatga ggcagaacag aaactacaag aaacaaaaag
     1081 gatacttgat tatttaaata ttgataatgc ttaaaactag gttatatatc aactaaacaa
     1141 ataagttaga ctataagcgt aagtcaataa gaaatatata aatatctaaa atattgactt
     1201 actcaataat aatatatagc attttataat acaaatgagt tgtcttaaaa tttatttttt
     1261 ttaatcaaat tttaagttca actccttttt tatattatta tagatatatc ctatattttc
     1321 ccaaaaaacg tattgaacat acaaattata ggaggtataa tgttatggag agagaatata
     1381 tgaaatgtat acaaaattga ttttaactgt attattgata attctcttta ctcttaccat
     1441 tactaatgat tgaagacagt agtatttatc ataggtcaaa gattccgaat atattaatca
     1501 tcatcatttt ctcaaattaa cagcaaacat actgatttgc gagttgtatt gtatacaaat
     1561 tatctagaaa atatctatta gattttccat gaaatttaaa tatttcgcga acgtatgaac
     1621 gtagaaacat acatgttgac aatccacatt tttaaatccc aaatgagctt tattaatggt
     1681 agagaatagg aagtaacaat attttataaa ggagaatact aagtatgaag aaaattagga
     1741 agttagctac caagttattg attacaacaa tggttttaat ctcaggtatg agtatgacag
     1801 tttatggtat gacagctaaa gaggtaacag caaagacgcc aaaaagctac gtcactggaa
     1861 ccaatagcgt atatggtccg aagttgtcac aagcccaact gaactcagta gcacaagcaa
     1921 cagcagattt tatgaacaag aaaatcacaa agaacatgac tacagatgct aagattttag
     1981 ttgcctacaa tcacattaaa aataacacaa catatgttga ctggaatgca gtagagggag
     2041 caaatactgc ctatacattg gttactaaaa aaggtgcatg ttcaggaatg gctaggagca
     2101 tgaaagcttt gtgtgatgct atgggaattg aatcttatta tgtacacagc acatcaaatg
     2161 accaccagtg gaatcttatc cgttttggtg atgggcgttt gtatcatgta gatattgatg
     2221 ctaataaatc agcaggaaag gatgtcatat acaagagtct tagccaccca ttaccatttg
     2281 ataagacagc atatccaaca gttggagcag tagcacaaac gcaaaaaaaa ccagcaccac
     2341 ctgggaagca cactatgtta ccacaccaag aaggggcaaa ggttgttgga aaatttggag
     2401 atataaagga taaacatgta atgtatgaag gtgttcgatg tgttgtaatt aattcatcag
     2461 taaatacagt tacatttatg ggtagtgaat caaatttaga cccatcagag cttacgattg
     2521 ctgtaatagg atttatgaac acaccatatg gaatgtttgc attagcgcca gaaagtaaac
     2581 ccgttgaata tccttttgaa tatgataagc cattttcttt agattttagt ggtaaaaatc
     2641 gttctggtgc agaattagcg aagtactgta aaaaaaatga tgtgactatt aaaatagaaa
     2701 tcactgatga aaaagctaat actggacttg gtcaaataat gtatattcga tatgaataat
     2761 gatttaatca tgacagtaga ataagttatg aacattgcgc cctcttacta ggggcgcatt
     2821 taatattata tctgatattt tgtagtcagg tcaactgctg gatttctccc ctttttattt
     2881 ataaaaatta ttatctctaa gcatctgagc atttttacga ttaactaaaa actgttttaa
     2941 ctcagtcaag cataggaata aaatagccct attttcaaat tctgttctgt caacaggtag
     3001 aggttggttt ttcatactaa gcattaatct cttcaattct tcaagaagaa gattgcctgt
     3061 ttcagcttca aattcagtat gacctatttt atgtatgaaa gcagagagga tatgagcttg
     3121 tggtggtgta gaatttagtt gagatacgta actatacaaa ttttctaaga tatcccgttg
     3181 actttttata atgtccatat gttctaagaa gaatctagta tcactcaata aagtattatt
     3241 aatattatcg taagtttcag aaatactgct gtcaataagt gaatttaatg tatataaatc
     3301 tctactatat ccattttctt ttttagggtt tacaataata tctgcaatgt ctataagtac
     3361 aatactcact tcttcctgta actttttttg aacttcatgg attttatgta tatttgttgg
     3421 aatatacata tttattaaga cacctattcc agttcctact gcaaatattc cagcttcgtt
     3481 taaaatccac ttaatagatg tttctccttg aagaaaataa tgggaggcaa tgactacaca
     3541 catggcaata acatcttgaa tatttaataa aaaacaaagt ggtataatta taaatataaa
     3601 tactgaaaat gaaatcaaat tatatcctaa aatattaaaa cataaatagg aaaaaatagt
     3661 acataaaaga aaaccataaa cctttccaat agagccttta agagtttctc ttttagtatc
     3721 ttttactgta agtagtacta taactccagc aaccattgaa tattctaatt ttaatagcca
     3781 agcaataaat atagcaagag aacatccaag agacaatttt attactttaa gtgaattaat
     3841 attattcaaa tgcaaacctc ctttaaacaa atatagtaaa gataatttta gcataaaact
     3901 aattttgttt aaaatatagt taaccatatt ttatttaaaa attattatac aaatcaataa
     3961 aaagataagt aagtgtggat acaaagatac ctttttaatg taaaatattg tagaatacaa
     4021 aatattataa tgaacacaaa ataattataa tctattaaat aaaaaatact ttaaattaca
     4081 attagagtag ttaataaaat aactgaaaat atatctatta ttattaacaa aaaataaaat
     4141 tatatagtta atgtaatttt ataattgatt tggtatggag atttttttct tttgtgttat
     4201 actatttatg aaagcaaata gaaacattaa aatacattat taaatatgta tgagaagttt
     4261 taagtagcct tattaatgaa cttgattatt gttcataata gcaaattgga ggagataaac
     4321 atgaaaatta ctgaaggata tatgcctttt gaaggtttta aaacttatta tcgtatagta
     4381 ggagaaaata cggaagggaa gaagccatta gtactacttc acggaggtcc aggttctaca
     4441 cacaactatt ttgaagtgtt agacaagata gctgaaagtg gtagacaagt tataatgtat
     4501 gaccaaattg gttgtggtaa ttcatttgta gaagggcatc ctgagttatt taatgcagat
     4561 acttggataa aagagcttat tgaactgaga aaacatctag ggcttgatga aattcatctg
     4621 ttaggtcaat cttggggagg gatgcaggct atttggtatg ctattgaata taaaccaaaa
     4681 ggtattaagt cttacatcct ttcatctact ctttcttctg caagactttg ggagaaagaa
     4741 caaaaaagaa gaatatcata tatgagtgag tctgaccaaa aagcattact tgatgcagta
     4801 aatactggag attactctag taaagaatac aatgatgcat tagaaagatt tatggaaatg
     4861 tattgtgcag gtgaagtgac agaagattct ccagagtgcc taagaagacc taaaaaatca
     4921 ggttctgaag catatattgt aggatgggga caaaatgaat tttctcctac aggaactctt
     4981 tctggatatg agtttacaga tagattacat gaaataaaag agccttgtct agtaactagt
     5041 ggagcaagag atttatgttc accatatatt gcaaagacta tgtatgatag aatacctaat
     5101 agtaagtggg agttattcga gtattcaaga catatgccat tcgttgaaga aaatgagaaa
     5161 tatatagaag tcttaactga gtggttagat gctaacgatt aaaaataata taaatttata
     5221 caaaagagag gctagacatg ttgtctagtc tttttggtat gataaaagtg taatagttta
     5281 tattataaac gatggtatat ttgtacttat tttaaaatct attgtgtcta agaaaaaatt
     5341 aatagttgta gtaatgagta taattgtaat taaatagtga gctttttata tgttcattca
     5401 agaataaatg attcatcatg aggaaatcat gataataaaa ataaatattg ttcaggaagt
     5461 tatcactatc cattgtggta gttatccagt tcatttacat gataatggag tatccttata
     5521 atggaggata gaagtatctg tagagcaaca acctttttta tatacaatat atatataaag
     5581 taatatatat tgtatataaa atttattatg atttactaag atttctaatt gacattatat
     5641 gtatttagag gtac
//
LOCUS       DAMKOJ010000145         5644 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000145 DAMKOJ010000000
VERSION     DAMKOJ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5644
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.154"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            34..885
                     /locus_tag="PC592_003432"
     CDS             34..885
                     /locus_tag="PC592_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HDF4057358.1"
                     /translation="MKNIISAKELISKLEQNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNNTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEKKVNVPSCTGKEIKPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1013..2626)
                     /gene="ggt"
                     /locus_tag="PC592_003433"
     CDS             complement(1013..2626)
                     /gene="ggt"
                     /locus_tag="PC592_003433"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDF4057359.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLIECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSRKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELKLEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPEHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVESEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2858..4795)
                     /locus_tag="PC592_003434"
     CDS             complement(2858..4795)
                     /locus_tag="PC592_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057360.1"
                     /translation="MTLFRIAMKNVKNSFFNYLMYFISIVFSVFIFFSFKSIEYNKAL
                     SSLGEKTRMSINTSSILIVAFVFLFIYYSNSFFFNRRSREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLT
                     IFIVIGIRNTIVIRNKRIIELFNKPPEKCRFKKFIKLKGALGVLLITISYLMSISYFI
                     AENIMFSVFILVTIIPGTFLFFSSVMYMIIDAVKKRKGFYYKGQNLIAFSELGFKLKS
                     NSSVLAIIAILIATSVTILGFTISLYYDIDRNISENYKYSYTINLGNSHVNNKIDKLL
                     DKYKKDNKIIFDKTIELIDKDINLEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELISKESVYYVSDSYKKILFKDFEIEKINLHFKDTSECDINLFTVQKTILEPEIN
                     SQATFDLIVVKDKVFNQLKLHGDSRLIRLIDIKNEKKELNLTLKLKNIVSENMEFTYP
                     FNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDRERYIMLT
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIVQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMITE"
     gene            complement(4782..5549)
                     /locus_tag="PC592_003435"
     CDS             complement(4782..5549)
                     /locus_tag="PC592_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057361.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRINEISRELNIESILDKYPSEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
BASE COUNT         1916 a          921 c          623 g         2184 t
ORIGIN      
        1 ataaaaataa tataaacata ggaggtacat tttttgaaaa acattatttc tgcaaaagaa
       61 cttatatcaa aactagagca aaatgataat ctagttgtaa tagattgtag atttgacctt
      121 attaatagaa cttatggtat tgattcttat aaaaaaggcc atataaaagg tagtttcatc
      181 ttagatatag acaaggattt atcatctcct acaaaagaac atggtggtaa aaatccttta
      241 caagaccctt taatactaaa agaaaaatta gaaaaaatgg gtgttgataa caacactacg
      301 attgtaactt atgatgatgg agatttaaat ggagcttgca gattattttt ccaattaaaa
      361 catttgggtc ttaaaaatgt ctatgtacta gacggaggaa taacatcttt cgtaaaagaa
      421 ggtggagaat tggaaaagaa agtaaatgta ccaagttgta caggtaagga aattaaacca
      481 aatataaata atgatttagt tgtcccaatg gagtatgtta aatctaaatt atacaaaaaa
      541 gatactgtaa taatagattg ccgtgctaat gaaagatacc aaggtttagt tgaacctgct
      601 tactcaaaag ctggtcatat accaagtgca aaaaattatt tttgtaagga tttaataaaa
      661 agtgactttg aaaatggctc acttaaagat atagaatttt taaaaaaatt ctttaaagat
      721 ttaaataatt atgatgaagt aattttatct tgtggttcag ggatatctgc ttgtgttaac
      781 agtcttgccc ttagagaact tgatatacct cataagattt atattggtag ctttagtgac
      841 tggattagtt atgatgacaa tgaaatcaaa actggccaag aataaggcta acaatatata
      901 aaatcatagg atagcttaaa ttttgtaaag gcgtcagtca ttgtagactt tcgcctttaa
      961 ttattatttc atatactctt taaatttatt atatatattt tagttgataa tattaataga
     1021 ctgcaatatg accatcacat cttgactctg tcccacagat ataactttcc tgttctgttt
     1081 taaatattat ttgacctcgt cccatgtcga cagtatcatg aatcactttt atttcatgac
     1141 ccttttcaat taatgaatct attatatgct ttggcatctc tgattcaact tctatttcct
     1201 ttccttttat ccactgccat cttggagcat ctaacgcttc ttgtggattt aatccaaaat
     1261 ctatcatatt tgttaatact tgaatatgac cttgtggttg cataaaagct cccattacac
     1321 caaatggtcc tattgcttta tcttctttac ctaaaaatcc aggtattata gtatgataag
     1381 gttttttaaa tggttttact acattatggt gttcagggtc taaattaaaa ttattacctc
     1441 tactatgtaa agcaatccca gttcttggta tcacaattcc tgaaccaaaa tttatgtaat
     1501 tactctgtat atatgaaacc atatttccat ccttatctgc agtgcaaagg tatactgtac
     1561 caccacaata tggctctcct gcagttggat acagagcctc tttattatca attaatagac
     1621 ttcttttttt ggcatactct tggcttagta attcctgaat ctttaccttc atgtgctcta
     1681 tatcagttac atatgtttta gaatctgcaa aagctagctt taaactttct ataatcttat
     1741 gtatgtcttc tacattttct atatttcctt ctagtttcag ttcttttaat atattaagtg
     1801 ccattaaaac tgttattcca tgcccatttg gtgggatttc aaatatttta tatcccttat
     1861 attctgtact tatcggttct acccatgttg gataaaaaca ctctaagtca ctctttctta
     1921 tagccccatt aaattttcta gaatattcat ctattttatc agcaagtctt cctctataaa
     1981 aactttcagc ttgagtattt gctatctctt ctaatgtact tgcctgttct tcacatataa
     2041 atatatctcc agcctctgga gctttaccat ctttagaaaa tgtatcaaac catggcttga
     2101 actcttctcc aataagttct ttctcatata gttcatatga ttttttccat actttagcta
     2161 cattaggaga tactacatag ccctctcttg catagtttat cgctggagat aaacattcta
     2221 ttaagctaag cttaccatat tttttattta attctgacca agctgcgggt ataccaggca
     2281 cagttactgc tccaaaccca tactttggca tttccttcat attattataa ttttttaatt
     2341 ccatattttc tggagcaaag ccactagaat ttaaaccata caatcgtttt tcttcctcta
     2401 tccaaacaag ggcatatgca tctcctccaa tcccattact tgtaggctct actactgcta
     2461 atgtagcagc tgttgcaact gctgcatcaa cagcatttcc accctttttt agtatttcaa
     2521 gtccagcttg agatgctaat ggtgttgatg ttgcaactgc tccattttta gcatacacga
     2581 catttcttat tgatgagtat ttatgttggt aggcattaaa cttcataaat ttcagctcct
     2641 cgtcattttt tatttgatat tctgcttaaa tttattatat aacatcaagt aatataactg
     2701 atacaaaatg atataaaata tagacttttt cctaacccta attttatcat taaataaata
     2761 tcttaagctc aattctagta ttttctattt gcacttaaat aaactatttt attcaaaaca
     2821 tacatctaat tattttaact taaaaataat ttattattta ttctgttatc atgtttagag
     2881 catattttaa agttaaaaaa taatatataa aatatcctat aaaataaatg actagagtta
     2941 tgataattgg tacaagtaat gaccttggta taaacttttg tactatagac atagcaaata
     3001 aattatgaac tgtacctaca actaatggca ttaaaaatat gacttttaac tgttttgata
     3061 ttattttctc aatatcttta ttatttgctc caagttttgt taacataata tatctttccc
     3121 tatcatcata tatatttgat aattgtttaa acaaaattat actacctgtg cataaaagaa
     3181 atactacaga taaaaatata cctataaaca gcattagacc acttaatttt atcagattgt
     3241 cataactttc aatactggat gtaaaattaa aaggataagt aaattccata ttttcactta
     3301 ctatattttt taattttaaa gtcaaattta gttctttttt ttcatttttt atatcaatta
     3361 atcttattaa cctagaatct ccatgtaatt ttaattgatt aaatacttta tcttttacta
     3421 caattaaatc aaacgtagct tgtgaattta tttctggctc taagatagtt ttttgtactg
     3481 taaacagatt tatatcacac tcacttgtat ctttaaaatg taagtttatt ttttcaatct
     3541 caaagtcttt aaaaagtatt tttttatatg aatcagaaac ataatacaca gattcctttg
     3601 aaattaattc ttcataattg ttattctgat attgtcttaa ttttttaaaa tcactttctc
     3661 tgataatatc tacagaagtt ctatcttcta tataactatt tccattttta tagtacattt
     3721 caagatttat atctttgtct ataagttcta ttgttttatc aaagattatc ttattgtctt
     3781 ttttatattt atctaataat ttgtcaattt tgttatttac atgagaattt cctaaattta
     3841 tagtataact gtatttataa ttttcactta tattcctatc tatgtcgtaa taaagcgata
     3901 tggtaaatcc taatatagtt acacttgtag ctattaatat tgctattata gccaacacac
     3961 tactattgct cttcaattta aatccaagtt cagaaaatgc aattaaattc tgtcctttat
     4021 aataaaaacc ttttctcttc ttaacagcat caataatcat atacatcact gacgaaaaaa
     4081 ataaaaaagt tccaggtatt attgtaacta atataaaaac tgaaaacata atattttcag
     4141 caataaaata actaattgac attagataag aaatagttat taataaaaca ccaagtgccc
     4201 cttttaactt tataaatttt ttaaacctac acttttctgg tggtttatta aataactcta
     4261 taatcctctt attcctgata actatagtat ttcttattcc aataactata aatattgtta
     4321 aaaacacagc tagtgtctga actaaagcct ttatacttaa gttcatattt actactatca
     4381 tttcattcat taattttaca agcatcatag tcataagctt tgaaaataac aatcctaaaa
     4441 atatacctat tagtattgca actatcccca tcaaaaaagt ttcatataaa aatatttttc
     4501 ctatctgatt ttttctcatt ccaagtaaac tataagtacc tacttctcga ctacgtctat
     4561 taaaaaaaaa tgagtttgaa taatatataa ataaaaatac aaatgccact attaaaatcg
     4621 aactggtatt aatgctcatc ctagttttct ctccaagtga actcaatgct ttgttatact
     4681 ctatagattt aaaactaaaa aatataaaca cactaaatac aattgaaata aagtacatta
     4741 aataattaaa aaaactattc ttcacatttt tcattgcaat tctaaataaa gtcatttttg
     4801 ttaactcctc caattaagga aactgtattt actattttat tatagaactc tctgttactt
     4861 tctcctttta caatttctgt aaatattatt ccatctttta taaatagtat cctattgcaa
     4921 aaactcgcac ttatagcatc atgagttacc atcaatattg ttttattact atctttgttt
     4981 aatttcaata gacagttcaa caaatctcta gcagatttag aatctaatgc tcctgtcggt
     5041 tcatctgcaa gtactaatga tggttttgtt gctatagctc tacatacagc tcctctttgc
     5101 ttttgtccac cagaaacttc actagggtat ttatctaata tagattctat atttaattct
     5161 cttgaaatct catttattct attttctatt actgatactc tttcattttt taaagaaaga
     5221 ggcaacatta tattttcttt tattgtaagt gtatccaaaa gattagaatc ttgaaataca
     5281 aatcctagat tatcacgtct aaaatccgcc aattcatttt gcttcatttt aatagtattc
     5341 tttccattta tataaatatc tcctgatgaa ggtaagtcta ttgtagaaat aatatttaaa
     5401 agtgttgatt taccagcgcc agatgacccc ataataccaa caaattctcc tttataaacc
     5461 ttgaaagtta ttcctcttag agcttcatgt tttgaacctt ttcttccata ctcctttttt
     5521 atattttcaa cagataatat ttcttccata attcataatc acctttcatc ataattagtt
     5581 atttgtcaat tctcacaaat atattatata tattaaaata gcttttaaac atttaattat
     5641 atta
//
LOCUS       DAMKOJ010000146         5414 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000146 DAMKOJ010000000
VERSION     DAMKOJ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5414
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.155"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(560..1966)
                     /locus_tag="PC592_003436"
     CDS             complement(560..1966)
                     /locus_tag="PC592_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4057362.1"
                     /translation="MDSVKYILKRFIGSSILISLLFIILNIAGFLLFSYMIFVSKYSV
                     DLDTSDSREIKSNLIMLEENLILKDGKFILNDSSKEVLHKNKIWAMLINNNGDRVWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEYPNGILVTGYPKDKYTKFNLTYTIKE
                     IKQFPMLIICMFLVNAIVIFLIALFIGLKMVKSIKPIINGIKLISNGEPVILKEKGIL
                     SDISKSINTVSKELQMKDEKLRNKDEARSNWIAGISHDIRTPLSMIIGYAGELEESRN
                     LSNKEQEQVSIICNQGVKIRELVNDLNLVSKLEYNMQVLNCDKIRVSTFLRELVSEFI
                     NDNLDNDFYIELDILNEDIIVDADKKLLKRAISNLIQNSITHNQQGCNIKVISKSDLD
                     FCYIIVEDDGKGMSQEKINSLLKSQNGLSEAYAKGQNHGLGILIVAGIINAHGGKLDI
                     TSIDGKGLKTILKLPIIK"
     gene            complement(2011..2718)
                     /locus_tag="PC592_003437"
     CDS             complement(2011..2718)
                     /locus_tag="PC592_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4057363.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRIFLASSCEEAV
                     RVFRNIKPDCAILDVVLPDGDGFSIMRKIRETSKMPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVSILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTSDSLCQAIWGDDMYGYENTLMVHIRRVREKIERTPST
                     PKYLLTVRGLGYKLMIN"
     gene            2879..3802
                     /locus_tag="PC592_003438"
     CDS             2879..3802
                     /locus_tag="PC592_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4057364.1"
                     /translation="MKHMEMIIRTQRLSKEYNKIFRVKDIDLRVPKGAVYGFLGPNGA
                     GKSTTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENM
                     IIMQRLLDLPKKNINEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKLPKLLILD
                     EPTNGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQD
                     IIKELHNRGQSQIAIKTNNIVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINNML
                     VHSNIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3802..4563
                     /locus_tag="PC592_003439"
     CDS             3802..4563
                     /locus_tag="PC592_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057365.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAISRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVASLNGIYL
                     SKFLCSAILVSVPVLIQVLSIVLFGYFRGVIESLSVFLLLKYILGTVFVNIAIIALHL
                     WIAIVIPNQMVAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDTNFSITILVFLIGILIYYIGRNHLLKKEV"
     gene            4575..5312
                     /locus_tag="PC592_003440"
     CDS             4575..5312
                     /locus_tag="PC592_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057366.1"
                     /translation="MLRKSVFGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSMLTAITQVFFVVFYIVAGNMFGFSGNIPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVANPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     AVCVSFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         1882 a          831 c          684 g         2017 t
ORIGIN      
        1 atttaaatat atatatatat atatgttatt tctaaaaata ctacacaaaa ctctacttta
       61 gtagaactta aagacgcaaa atacttcaat ttaaaacatt tatcgtactt taaataaata
      121 actataataa aatatacata cattagttac ataaaagcta ttataactac acgtaacagc
      181 gtacaattaa aactttttta gcatgtcatt atattttttc ttaaaattaa aaaacactat
      241 atcataattc tattttagta gaattttttt gtcaataata aaattaaata ttaattaaaa
      301 aataaaaaaa atggaattat ctaaagaatt taataacctt acaataattc caaaatatta
      361 tttctatgaa aattttgata ccatgagtaa cttagctata agcgcataaa gcacaagtta
      421 ctctttagtt taataaaact tgacaagaaa agaatttatc cttattctac tctaatagag
      481 ttactttgtc aataaagaat aaaattattt tcaaaatatt tccattcttc atttttatct
      541 gtcattattt tataaaatat cacttaatta taggtaattt tagtattgtt tttagtccct
      601 taccatcaat actcgtaata tccaatttgc ctccatgtgc attaataata ccagccacta
      661 tcaaaatacc tagaccatga ttttgacctt tagcatatgc ctcacttagt ccattttgac
      721 tctttaataa actattaatt ttttcttgac tcataccttt tccatcatct tcgacaatta
      781 tatagcaaaa atctaaatca gacttagata taacctttat gttacaccct tgttggttgt
      841 gagttatact attttgtatt aaattactaa tagccctttt taataatttt ttatctgcat
      901 ctacaataat atcttcattt agtatatcaa gttcaatata aaagtcatta tccagattat
      961 catttataaa ctcagaaaca agttctctca aaaacgtaga aactctaatc ttatcacaat
     1021 tcaatacttg catattatat tcaagtttag acactaaatt gaggtcattt actaattctc
     1081 taattttaac cccttgattg catataatag acacttgctc ttgctcttta tttgaaagat
     1141 tacggctttc ttcaagttct ccagcatatc caattatcat tgaaagtggt gttcttatat
     1201 catgagatat tcctgcaatc cagttggacc tagcttcatc tttgttccta agcttttcat
     1261 ctttcatttg caattcttta gatacagtat taatagattt tgaaatgtca ctcaatattc
     1321 ccttttcttt gagaattact ggttcgccat ttgatataag ctttatccca ttaataattg
     1381 gttttataga tttcaccatt tttaagccta tgaatagagc tattaaaaaa ataactatcg
     1441 cattaaccag aaacatacat attattaaca taggaaattg ctttatttcc ttaatcgtat
     1501 aagtaaggtt aaacttagtg tacttgtcct ttggataacc tgttactaat attccatttg
     1561 gatattccca tacatacaca ggataatcct ttaaaaagaa ccttgaaaac tttgctacat
     1621 ctgtcaaagt ataatgactt ggaatttctt ttggtaaatc aaatccccat actctatctc
     1681 cattgttatt aattaacatt gcccaaattt tatttttatg tagtacttcc ttactagaat
     1741 cgtttaaaat aaactttcca tcttttaaaa tcaaattttc ttcaagcata atcaagttgg
     1801 attttatttc cctactatca cttgtatcta aatcaacaga gtatttggat acaaatatca
     1861 tatatgaaaa cagaagaaaa cctgctatat ttaatataat aaaaagtaat gaaatcagga
     1921 tacttgaacc tataaatcgc ttcaatatat actttacact atccaaaatt aaatcactcc
     1981 tcttgatttc ttttatccta atagctaaaa ttaattaatc atcaacttat atccaagacc
     2041 tcttactgta agaagatatt taggtgtaga tggagttctt tctatcttct ctctaaccct
     2101 tctaatatga accataaggg tattttcata tccatacata tcatcccccc aaatagcttg
     2161 acatagtgaa tcactcgtaa caattctacc tttattttca tacaacttta aaagcagtga
     2221 atgctcttta gctgttagag aaatctcttg cccatctttc tcaacacatg cactatttaa
     2281 atttacaaca acagaatctc ccagtttaaa tactggtaac tcttcttctt ctataggcac
     2341 atatacacga tttaatatgc tcacaagtct taaagtaagt tcctttggta aaaatggctt
     2401 tactatataa tcatcagctc ctaagcccaa accaatcaat ctatcctcat cttcgcctct
     2461 tgcagaaaga aaaataactg gcattttaga tgtctctcta atttttctca taatagagaa
     2521 accatctcca tctggcaata caacatctaa aattgcacaa tctggcttta tatttctaaa
     2581 taccctaaca gcttcttcac aacttgatgc taaaaatatt ctactaaatc cctcttttct
     2641 taggatttca tctatcattt ttaataattc cttgtggtca tcaaccacaa gtattttttt
     2701 atcttttatt gactccacaa tcatcaccct cctttagtat accatatacc attttcacag
     2761 ctttgcctaa atagactatt taaggctatt gtaaggtaaa cttcagctaa ttgaaatgta
     2821 gttcatttat tatacttata taagctaaaa aaatcaataa acacagatta aaaaggggat
     2881 gaaacatatg gaaatgataa ttagaacaca aagactttca aaagagtaca ataaaatatt
     2941 tagagtaaag gatatagacc taagagttcc aaaaggagct gtatacggtt ttttaggtcc
     3001 taatggagcc ggaaaatcta ccactcttaa aatgcttctt ggacttgcta aacccacaca
     3061 aggaaatatt aatattttag gtaaagaatt aaatgaaaaa aatagaatat caattttaaa
     3121 agatataggt tctttaatag aatctccatc atactatggt cacctgacag ggcttgaaaa
     3181 catgattata atgcaaagac tcttagattt gcctaaaaaa aatataaatg aagcattaaa
     3241 aattgtaagg ttagaaaatc aaaaaaataa aaaagttagt caatattctt taggtatgaa
     3301 gcaacgtctt ggcattgcca tggctataat gaaacttcct aagttattaa tacttgatga
     3361 acctacaaat ggacttgacc cagcaggtat tgaggaaatt agagaattaa taaaatctct
     3421 accagaaaaa tacggtatga cagttctaat ctctagccat cttttaagtg aaattgacca
     3481 aattgccaca tcaataggaa taataaatca tggcgaactg gtttttcaag atatcataaa
     3541 agaacttcat aatagaggtc aaagtcagat tgctatcaaa actaataata ttgtatctgc
     3601 acaaaagcta ttgaatacta aaggatatat gtcacttata caagatggat atttaactat
     3661 tgaaaattta aaagactcag atgttgctaa aataaacaat atgcttgtcc attcaaatat
     3721 agatgtattc agaatagaag aacataaaaa gagcttggaa gatatcttcc tagaacttac
     3781 tggtaaggcg gtgactttat aatgaaatac cttggtctag aattttataa acttaaaaga
     3841 aagaagatta ttctgatgac ctttttattt gtagctgttg aaataatgtg gtgcatcata
     3901 aattcaaata gagctatttc acgtaatcca gatatgttag gtggatttga atattcatat
     3961 atgcttatga gttttgcaag tttaaatggt ctattctttc ctatcttaat atcaataatt
     4021 acatcacgta taagcgatat agaacataaa ggagatacat ggaagctttt aaaatcttct
     4081 gtggcatcct taaatggtat ttatttatct aaatttttat gctctgctat tttggtatct
     4141 gtacctgtat tgatacaagt gttgtctatt gtgctatttg gatattttag aggagtaatc
     4201 gagtcacttt ctgtcttttt acttttaaaa tatatattag gaacagtttt tgtaaatatt
     4261 gctatcattg cactgcacct atggattgca attgtaattc caaatcaaat ggttgcaatt
     4321 acatttggta tgattggcag ttttataggt ttgacatcag gattgtttta tcaaggtatt
     4381 cgtagattgt ttatatggtc ttattaccta gagttatcac ctttaagtta cgcttatgat
     4441 aatgttttag gttcatctgt ttatagaatt gatacgaatt tttctattac gattttagtt
     4501 ttcttaattg gaatattaat ttattatatt ggaagaaatc atttattaaa aaaagaagta
     4561 taggagggat ttaaatgtta aggaaatcag tttttggaga aattctaaag ttaaaaaatt
     4621 cttttatatg gtatgtatta ttagctttgc cacttataag tgtattgatt ggctctggta
     4681 atttttatct aaatcaaggc atactcaaaa aagaatggta cagcttatgg actcaagtta
     4741 gtctttttta tggggaattt ttctttccta tcttaatcgc aatcttttgt gcatatattt
     4801 gtaggcttga acatatgaat cataattgga ataatgtaat gacattgcca gttaatttaa
     4861 aaaatatctt tttatctaaa cttacagtag tttcaatgct tacagctatt acacaagttt
     4921 tctttgttgt cttttatatt gttgcaggaa atatgtttgg tttttctggt aatataccta
     4981 aagaattgac tggttggatt gctaaaggtt ggattatttc catttcaata gcttctatac
     5041 agttatacat gtctataaag attagaagtt ttgcaacacc tattggtatt agtctttgcc
     5101 tttctttatt tggtatggga ttaatagtag caaatcctgc tgttggtata tttttccctt
     5161 attctatgtt aggtagtgct atgggggtta taaagcaatc tgctttaaat gttaatgaca
     5221 ctatagttgc agtatgtgtt tcatttatta ctactatagt attttctgaa attgccaata
     5281 gaaattttag aaagaatgat gttatttctt aatggtaaac gttagatatt tttttgttta
     5341 aaatttatat tctttttagt tgaaatatat atccctttta gttaaaaatc tatatctttt
     5401 attttaattt tata
//
LOCUS       DAMKOJ010000147         5351 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000147 DAMKOJ010000000
VERSION     DAMKOJ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5351
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.156"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            106..1596
                     /locus_tag="PC592_003441"
     CDS             106..1596
                     /locus_tag="PC592_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF4057367.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEENEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEEKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMENGEDFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1876..3372
                     /locus_tag="PC592_003442"
     CDS             1876..3372
                     /locus_tag="PC592_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF4057368.1"
                     /translation="MFEFETQLKRLKHEVLTAVAKLSIEENLTKENIQKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVGLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFIDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKIFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKCLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSIQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEGVNLER"
     gene            3506..4420
                     /locus_tag="PC592_003443"
     CDS             3506..4420
                     /locus_tag="PC592_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4057369.1"
                     /translation="MKKIILKDILFLVTTLSLIVILLIVVNITANGKIKSTIKSYLKS
                     DKNSVSQNDIQSSTKNTEFKTTILNTGKSDCILVEIGDKVIMIDSGEDKNGKQIVDRL
                     KEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKA
                     DIEPVLLKENMNIVINSAEINIQSALKSKYESSNDYSIITSISYGAHKFLFAGDAEEK
                     RLSEFINGNTLKYDFVKIPHHGRYDKLTEAFLESISPKYAVITCSEKKEPDEEILKIL
                     EKLNIKTFLTSNGEVVINSDGKTLNVNQ"
     gene            4538..4729
                     /locus_tag="PC592_003444"
     CDS             4538..4729
                     /locus_tag="PC592_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057370.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            4951..5301
                     /locus_tag="PC592_003445"
     CDS             4951..5301
                     /locus_tag="PC592_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057371.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGKVNEAEEILFDKAKTVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
BASE COUNT         2125 a          545 c         1021 g         1660 t
ORIGIN      
        1 gataaaataa aatttaaaca tataatattt tatgtatata ttaataaaag gaaatattgt
       61 gttataatgg tatcgtataa aatcatttac gggggtggta ttaaaatgtt tcaatttgaa
      121 acacaaatac acaaattaag acatgatgtt ttaactgcaa tagctagact cggaaaagaa
      181 gataacctta ccagagaagc aatggataat attcagtatg aaataataaa aggtgagaaa
      241 cctacataca gatgctgtgt ttataaagaa agagctataa tatctgagag agtaaatgta
      301 agtatgggat tacaaccagg tcaagataag atagatttag atacaatgga tatagaagaa
      361 aatgaacaaa ttatatatat tttggaagct gcatgtgaca gttgtccaat aaatgaattt
      421 acagtaacag atatttgtag aggatgtcta gcacatagat gtaaagaagc ttgtaaattt
      481 ggagctataa cacatgtcgg aggaatggcc tatataaatc atgaattatg caaggcttgt
      541 ggaatgtgta aaaaagcttg tcaatatgat gccatctcag aggttgttag accatgtaag
      601 agtgtttgcc caactaacgc cttagggttt gatagagaaa atatgaaggc tatgatacat
      661 gaagagaaat gtttaaactg tggagcatgt atgtcagcat gtccatttgg agcaatatct
      721 gataagagtt tgatagctcc tgtagctaga aaattagttc aaaaagagaa aatgtatgca
      781 gtagtagctc cagctataac aggtcaagtt gaagcaaatg ttacatatgg tcaaataaaa
      841 aatgctataa aatcactagg atttgttgat gtattagaag cagcttgtgg agcagatgca
      901 gttacagttc acgaaagctt agaatttgct gaaagaatgg aaaatggaga agattttatg
      961 acaaattctt gttgtccagg atttgttggc tatatagaaa aaacataccc aaatcatgta
     1021 ggaaaaatat cttctacagt atctcctatg atagctagtg gtagatttat aaaaagtcat
     1081 gagccagatg ctaaagttgt attcatagga ccatgtacag ccaaaaagag tgaggcagct
     1141 aagaaagaat taaaaggagc tgttgattat gtacttactt ttgaagaaat aatggcatta
     1201 tttgaggcat ttgatataga cttggctaag tgttcaaatg aagatataga tgatgcatca
     1261 atttttggaa gaggttttgg agctgctggt ggtcttacaa aggctataga aaattatctt
     1321 gctgaaaaag gtattggtgt taattttgaa cctgtaaaga tttctggttc aagagaaatc
     1381 aagaaaacta tgactatggc taatttagga aagctagaag gtaattttat agaaggaatg
     1441 atgtgtgaag gtggttgtat aaatggttct ggtaaattct tatcaggtgc aaaggttaaa
     1501 gccacttttg atagaaaaaa ttctcaatca actaagaaga gtgtcttagc aaatacaaag
     1561 ataaaagatt ttagtaatat aaatttagaa aaatagagat aatacaaagc aacaaaaata
     1621 catattgtta atagagttgt tctaagttga agtttaactt taggacaact ctatttttat
     1681 ttatatattt aattattgaa caactaaaat aaaaattata tacgcttaaa ataaaaatta
     1741 catatataat attttgtata taacttaaca aagtatatgc ctatgttata ataatttatg
     1801 gaaataaata aaatatacaa tatacataac agtagaaata tagcaaaaag atgtgattta
     1861 tagggaggat tacttatgtt tgagtttgaa acgcaactaa aaagattgaa acatgaagtt
     1921 ttgacagcag tagcaaaact atctattgaa gaaaatttaa caaaagaaaa tatacaaaaa
     1981 attccatatg agataattaa aggagaaaag gcgagatata gatgctgtgt ttataaagag
     2041 agagaggtag ttcttgaaag ggcgcaactt gcattaagct taactccaaa tagtaaatat
     2101 ggagatataa atccagattc agttggtttg gacacagacg agcaaattat atatatagta
     2161 gaagcagcat gtgatagatg tccaataaat gaatttacag ttacagaact ttgtagagga
     2221 tgtttggctc atagatgtaa ggaggcatgt aaatttgggg caatttccta tataaatggg
     2281 agagcatata taaatcatga tttatgtaag gcttgtggaa tgtgcaaaag ttcatgccaa
     2341 tatgatgcta tatcagaagt tgtaagacct tgtaagagtg tttgcccaac aggagctttg
     2401 gattttaata gaaacactat gaaagccatg atacatgaag ataattgtat aaattgtgga
     2461 gcatgtatgt cagcatgtcc atttggagca atatctgata agagtttaat agcacctgtt
     2521 gcaaaaaaac ttgcaaaaaa ggaaaatatg tatgcaatag tagctccagc tataacaggt
     2581 caaatagata gtaatattac atatggtcag ttaaaaaatg ctataaaatc attgggattt
     2641 atagatatga tagaagcttc ttgtggagca gatgcagtta cagttcatga aagtaatgag
     2701 cttattgaaa gaataaaatc aggagataat tacatgacaa attcatgttg tccaggattt
     2761 tttaagtata tagagaagat attcccagat gaaaaagata gaatatcatc tacagtgtct
     2821 cctatggtag caacaggaag attagtaaaa aaaatagatt ctgatgccaa ggttgtattt
     2881 ataggaccat gtacagctaa aaagagtgag gcaacagaga aatgtttaaa agattcagta
     2941 gattatgtac ttacttttga agaactaatg gcattatttg aagcatttaa tatagattta
     3001 tcaaaatgtt caaatgaaga tataaatgat ggttcgattt ttggaagggg atttggagca
     3061 tctggtggac ttgctaaatc aatacagaac tatattgctg aaaaggggct tagttttgat
     3121 tttgaaccta taaaagtatc tggtccaaga caaattaaaa agacaatgac aatggctaaa
     3181 ttgggaagat tagaaggtaa ttttatagaa ggaatgatgt gtgaagaagg ttgtattaat
     3241 ggagcaggta agtttttatc aggtgtaaaa gctaaaaata cttttgatag aaaaaatgga
     3301 caatctacta aaaagagtgt tttatctaat gataagatta aagaatttga aggtgtaaat
     3361 ttagaaagat aatcattttg atacagtcat ttttttatca tgccacaaat atgcctaaaa
     3421 tttgcccctt ttatatgtgt attttaaaac attaagattg ctatactata aatatgtaat
     3481 aaataaaatt tataggagct tttggatgaa aaaaataata ttaaaagaca tcctgttttt
     3541 agttactaca ttatctctaa tagtaatatt attgattgta gtaaatataa ctgctaatgg
     3601 taagataaaa tcaacaataa aatcttattt aaaaagtgac aaaaatagtg tgagtcaaaa
     3661 tgatattcag agtagcacaa aaaatactga atttaagact actatactga acactggaaa
     3721 gtctgattgt atattagttg agataggtga caaagtcata atgattgata gtggagaaga
     3781 taaaaatgga aaacaaatag ttgatagatt aaaagaaaaa ggaataaata cacttgacta
     3841 tttgatttta actcatttag ataaagacca tataggtgga gtagatagtg tgttatctag
     3901 tgttaaagta aagaatatta tacaggcaaa ttataagaaa gatagtaagc aatatgatga
     3961 atatattgac tcgcttaaaa aggctgatat agaaccagta ctactaaaag agaatatgaa
     4021 tattgtaatt aatagtgcag aaataaacat acaatcagct ttaaaaagca agtacgaaag
     4081 ttcaaatgat tattcaataa ttactagtat aagctatgga gcacataagt ttttatttgc
     4141 aggagatgca gaggaaaaaa ggttgtcaga gtttataaat ggaaatactt taaaatatga
     4201 ttttgttaaa ataccccacc atggaagata tgacaaatta actgaagcat ttttagaatc
     4261 tatttcacct aaatatgctg ttattacctg ttcggagaaa aaagaaccag atgaagagat
     4321 tttaaaaata ctggaaaaat tgaatataaa aacatttttg acttctaatg gagaggtagt
     4381 tatcaacagt gatggtaaga cgttgaatgt gaatcaataa ttttttttaa aatatctaaa
     4441 aaaattttaa aaaatcatta gcaaatatta ccccttaaac atagtatatt ttaggagctg
     4501 aaactccaca tacaaaatgg ctaggaggta acatattatg ttggatagat tttttggtga
     4561 aggcggattt ggtggatgtg cttggtggat aataatatta ttcttcttat tcttagcatt
     4621 ccaagattgt tgggctgaaa tggacttatg tgcatggata cctttcttaa tattattgtt
     4681 aatactttgt gaatgtggtg acgtttttga tggaggatgt ggatgctaaa aaaatcaatt
     4741 tagatgattt aacaaagctt ttggtgggta taaacaaaat accaaaccaa tcacaatcta
     4801 gtgtttgaag gtagtcggaa atcccccgct accttctttt tttattgtta aaatttattt
     4861 ttgtattatt tcatttacat ataataattt ttactataaa gtctgatata attaaaaaga
     4921 aaataaattt tatttatagg agatgtaaac atggctatag tggataagat tttcaatgag
     4981 ataaaactta tggttgcaag acttttattg gggaaaaaat acagtgaata tgaagaaaaa
     5041 gatttagtgt ataatacaga agaagaagtt atacttataa ctttaaaaag attagttttt
     5101 cagggaaaag taaacgaagc agaagaaatt ttatttgata aagctaagac ggtaaatagt
     5161 gaaaatatgc aatatatagc aatagaattt tatactatgc ttatggagaa aactgatgaa
     5221 gaattagaag ctatgaattt ttctaaacaa gaagtttatc aagggataga agatattagg
     5281 aaagtgttga atttagagta aaagatatat gaaaatattg aaataaatta atactaaggt
     5341 gagaatatta t
//
LOCUS       DAMKOJ010000148         5067 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000148 DAMKOJ010000000
VERSION     DAMKOJ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5067
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.157"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(214..1398)
                     /locus_tag="PC592_003446"
     CDS             complement(214..1398)
                     /locus_tag="PC592_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF4057372.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMENNGIKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCKYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPIFIDTKKENDFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYSGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKAIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSTDIDNMVKTYKSRRDLIKSKLDSIENIGYVNPNGAFYAFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLNKLKEFVYKI
                     MA"
     gene            1771..4122
                     /locus_tag="PC592_003447"
     CDS             1771..4122
                     /locus_tag="PC592_003447"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HDF4057373.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDEELVNKMQNFAFEESYKETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDELGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRDKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4144..4683
                     /gene="nrdG"
                     /locus_tag="PC592_003448"
     CDS             4144..4683
                     /gene="nrdG"
                     /locus_tag="PC592_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDF4057374.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEVIAREAKTNGLDVWSYTGF
                     TFEQLLDKRNSAYFKNLNLLKQIDILVDGKFVAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         1958 a          576 c          810 g         1723 t
ORIGIN      
        1 taataaattt agaatttaac ctatatagtt taacttaata atttaatgaa aaaaataaaa
       61 gacttactga tttttaaatc tataagtctt ttatttttta tttaatattt aaattaagtt
      121 gttgaatata tcttatatta cttactttat atattgatta tcattaggtt aagacccata
      181 tattgtatca attactattt atttaaattg ttattatgcc attattttat atacaaattc
      241 ttttaattta tttaatccag ataagaatgt attttcactg caagcataag atatacgaat
      301 atatttatcc ataccaaatg ctataccagg aacaactgca acattatatt cttctaaaaa
      361 ttgattacaa aattctatag aaaaactatc tttatattca aatttctcag atactttaga
      421 aaggtctata aatgcataga atgcgccatt tggattcaca tatcctatat tttcgataga
      481 gtctagtttt gatttaatta aatctcttct agatttatac gttttaacca tattgtctat
      541 gtcagttgag caatctttca aggctccata agctatgtat tgtgctgtca aacttgggtg
      601 agatataaga tgtccttgta tagaactcat tgctttagca atcgctttat tagatgcagt
      661 ataccctaat cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt
      721 tatatcttta gcttcttcgc ttaatgatgc aattgatgta aattcgccac tgtagcatat
      781 tttttcatat atttcatctg ctaaaatata tattttattt tgtatacaca catctactat
      841 ttctattaat tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac
      901 aagaattttt gttttatctg ttatagattt ttcaagttct tcttttgtca gtttaaagtc
      961 attttctttt ttagtatcaa taaaaattgg aacagcatta actaacttaa ccatttcagg
     1021 ataactaacc caataaggtt ttggcaataa gacttcatct ccttcgtctg ttaaagctag
     1081 taaagtattt gttattgagt tttttgctcc gcttgataca actatttcgt ctattgaata
     1141 tttacagttg ttttcctcaa taagtttttt acatatttct tctctaagta tttttaatcc
     1201 tggaactaaa tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc
     1261 gttattaggt acattaaaat caggttctcc tatactaaga tttattactt taattccatt
     1321 gttttccatt tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt
     1381 tagtcttttt gataacataa aatgcctcct tttaaattat tatttatatt atacgacaat
     1441 tttaaagaat ttacataagg aaatttgtag atatatacat taatatatat aatagaatac
     1501 actttttgcc taaaattagt gtaaaaaaaa gagaaaaaaa ttttgacttt caaagttgtt
     1561 agaaacgcta ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact
     1621 attatgtaca aatttggtaa tcttaatata gtaattatta agatagtccc tttaacttag
     1681 ttgaagggga tttttttaga cttaatatac tacatatagt ggtatgtgga ttaacaaaat
     1741 acaatatata gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga
     1801 agagtaattc catttaatga agatagaata acaagagcta tatttttagc agcaacgaat
     1861 gttgcagaaa gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa
     1921 gtaataaagt ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa
     1981 gattctgtag ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata
     2041 atatacagaa ctgaaagaag tagaataaga aattcaaaaa caagattgat gaaggcaata
     2101 gaggaaatta cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt
     2161 aatggtaata cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt
     2221 tgtaaaactc atatattaaa accagaacat tcttttgctc atgataatgg agatatacac
     2281 atacatgata tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa
     2341 aaactattca atggtggatt ttcaacagga catggttttt taagagagcc acaagatata
     2401 ataagttatg gagcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga
     2461 ggtcaaagta taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag
     2521 aaattctaca taggaaattt agctaaagcg ttgaagttat ttaaaggaat tgaaaataat
     2581 gatgtgataa agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt
     2641 aagagagatg aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata
     2701 gatgaggaac ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta taaagaaact
     2761 gataaaaaaa catatcaatc tatggaagca tttatacaca atctaaacac aatgcactct
     2821 agagcaggtg cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa
     2881 ggaagaatgg taactaagaa tcttctatta tctcaggaaa gaggtttagg taatggagag
     2941 acaccaattt ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa
     3001 gaccctaatt atgatttatt taaattatca tgcagagtat cagctaaaag actattccct
     3061 aattttagtt ttttagatgc accttttaat gcaaaatatt ataaaaaagg tgaaccagat
     3121 acagaggcta catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa
     3181 accgttagtg gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata
     3241 aaacatggta ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat
     3301 gagaagataa acttaattat agaacaatta ttggaacgtc ttgaggttca aggaaataaa
     3361 aagatgaaga attttccatt cttaatgggg caaggtgtat ggaaaggttc tgatgaatta
     3421 ggtccagaag atacattaaa agaagtaata aaacaaggaa cattgacaat tggatttata
     3481 ggtttagcag aatgtcttat tgctcttata ggtaaacatc atggagaaag taaagaagct
     3541 caagaattag gcttaaagat agtgtcacat atgagagata aaatggatga agcaacagac
     3601 aaatataaat taaatttctc tttaatgggt actccggcag aaggtctttc aggtagattt
     3661 actaaaatag ataaaaaagt ttatggggaa attaaaggta ttacagataa agaatactat
     3721 actaattcat tccatgtacc agtttattac aatataagtg catatgataa aattgagata
     3781 gaagctccat accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga
     3841 gatccatctg ataatctaga agcttttgaa actgttataa aggctatgaa agatttaggt
     3901 ataggatatg gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt
     3961 gtaataacaa gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa
     4021 ttcgaaagaa taagaagaat aacaggatac ttagttggta cagttgatag atttaataat
     4081 gctaaaaaag cagaagtaag agatagagta aaacatagat agttttattt gggggaataa
     4141 gttatgaaaa taagaatgtc atctactata agttatgaca gcatagttga tggaccaggg
     4201 ttaagaatgg tgatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct
     4261 caaacgcatg atttatgtgg aggattttat atggatacag aagaaattat aaataaagta
     4321 aaatcattga aattacaaaa aggtattacg ctatcaggag gagaaccatt tttacaacca
     4381 gaaccattag aagtaatagc gagagaagct aaaacaaatg gactagatgt atggtcatat
     4441 actggattta cgtttgaaca actgttagat aaaagaaata gcgcatattt taaaaattta
     4501 aatttactaa aacaaattga tattttagtg gatggaaaat ttgtagctga aaaaaaagat
     4561 ataagcttaa aatttagagg ttcatcaaat caaagaataa ttgatgttca aaaaagtttg
     4621 aaatataaaa aagtgttttt ggttgaacaa tatatgaaag atgatttgtc tatagcagaa
     4681 taaaatataa ataaacagga gtaaatatat gcttatattt actcctgttt atttgcatat
     4741 aatatttcaa gcttgtatga tgtaacaatc aaaccaaaat acttattgta tatctgaaat
     4801 taagtttttt atagtttaga ggtgttttat gtatattaca aagggtatac catacattat
     4861 ttaatcgatt cttatgccaa gaaacaatta atttacagaa atttttaatt gttacaatat
     4921 aaatatttag ataagttata aaatgttgat aaataattta gaaagtttat taatccaata
     4981 ttatgtatgt ttatattaag taatcaagta gtctaaaaaa tgaaaaaggt ttaaaataag
     5041 tattttaact aaatgtataa gagttaa
//
LOCUS       DAMKOJ010000149         5030 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000149 DAMKOJ010000000
VERSION     DAMKOJ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.158"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     misc_binding    12..274
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            349..3015
                     /locus_tag="PC592_003449"
     CDS             349..3015
                     /locus_tag="PC592_003449"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF4057375.1"
                     /translation="MENTNLSKTYNPKEFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPEKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDTNAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            3439..4149
                     /gene="rgaR"
                     /locus_tag="PC592_003450"
     CDS             3439..4149
                     /gene="rgaR"
                     /locus_tag="PC592_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF4057376.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKKRYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         1988 a          492 c          892 g         1658 t
ORIGIN      
        1 aatatgtaat attaaagact gagaagaaga ggagtaagta aatactacta aaagagagga
       61 aaattcactg gctgtaagat tttctaagta taagatttac tgaatgtagc tttggagttt
      121 ctaaactgaa ctatgagtaa gtttagacgg ttagaaccgt taaattcttt gagagtcaaa
      181 gtttataaaa taatattaac aaataattta attatacgtt aatgtatttt aagctttgga
      241 attaaggtgg taacgcgagc ttttcgtcct ttttgaagag gatgaagagc tcttttttat
      301 ttctaaagat atttaaaaat ttatttataa aatacaggag gcaggacaat ggaaaatacg
      361 aatttatcaa aaacttataa cccaaaagaa tttgaggcta ggctatataa aaaatggatg
      421 gatgaagggt attttaaatc taaaccaaat ccagataaaa aaccatttac aataatgatg
      481 ccaccaccaa atataacagg gcaattgcat atgggacacg ctcttgacca tacacttcaa
      541 gatatattaa ttagatggaa acgtatggat ggatatgaag ctttttggct tccaggaact
      601 gaccatgctt ctatagcaac agaagttaaa gttgttgaaa gaataaaaaa acaagaaggt
      661 aagacaaagt atgaaatagg tagagaagaa tttttaaaga gagcctggga gtggaaagat
      721 gaatttggag gaaaaatatc taaccagctt aaacaattag gtgattcttg cgattgggat
      781 aaagaaagat ttactatgga tgaagggtgt aatgaagcag ttatagaatt ttttgtaagc
      841 ctatatgaaa aaggtcacat atacagagga aacagaataa taaactggtg tccagattgt
      901 aaaactactt tatcagatgc agaagttgaa catgaagaac atgacggaaa tttttatcat
      961 ataaagtatc cactaaaaga tagtgaagac ttcttagaaa tagctacaac tagacctgag
     1021 acaatgatag gtgatactgg tatagcagta aatccagagg atgatagata taaacattta
     1081 ataggaaaaa cagcaatact tccattggta ggaagagaac ttccaatagt tgcagatagt
     1141 tatgttgatt tagagtttgg aactggtgca gttaagatga ctccagcaca tgaccctaat
     1201 gattttgaag taggactaag acataatctt gagcagttaa atactatgaa tgaagatgga
     1261 actatgaatg aagtttgtgg aaaatatgaa ggtatggaca gatttgagtg tagaaaagct
     1321 atcgtagcag acttaaaaga acaaggttat ctaattaaga taaaagagca taatcataat
     1381 gtaggaactt gttatagatg ccatacagta gttgagccta gattatcaga gcaatggttt
     1441 gttaagatgg aagaacttgc aaaaccagct atagatattc ttaaaaaagg agaattagaa
     1501 tttgttccag aaaaatttga taaaacttat ttacaatggc tagaaaatat aagagattgg
     1561 tgtatatcaa gacaattatg gtggggtcat caaataccag cttattattg tcaagagtgt
     1621 ggagaaattg tagttgctag aaaaatgcca gataagtgtc ctaaatgtgg aagcactcat
     1681 tttaaacagg atgaagatgc actagatact tggttcagtt ctgcattatg gcctttctct
     1741 actctagggt ggccaaataa gactgaagct ttagattatt attatccaac aagtgtactt
     1801 gttacaggat acgatataat attcttctgg gtagttagaa tggcatttgc aggtatgttc
     1861 tgtatgaatg aaaagccatt tgaccatgtt ttggttcatg gattagtaag agattctcag
     1921 ggtagaaaaa tgagtaaatc tttaggaaat ggtatcgacc cattggagat aatcgagcaa
     1981 tatggagctg atgcactaag atttacatta acaactggaa attccccagg aaatgatatg
     2041 agattctata tggaaagagt agaatttgct agaaactttg cgaataagtt gtggaatgca
     2101 tcaagatttg tatttatgaa tattgatgaa gatataatta aaaacatgac tagagaaagt
     2161 gttaaagagg acttaactct agctgataaa tggataatat caagagcaaa taatattgta
     2221 aaagaagcaa ctaataacat ggataagttt gacttaggaa tagcacttca aaagatatac
     2281 gattttactt ggtcagaata ctgtgattgg tatatcgaaa tggttaaacc tagattgtac
     2341 ggggaagata caaacgctaa atctgcagca ttatatacat taacttatgt tcttgaaaag
     2401 atattaaaat tattacaccc atatatgcca tttataacag aggaaatata tactcatctt
     2461 cctactgttg aaggatgtat aatagtatct gaatggccaa aatataatga agaagataac
     2521 atggctgaag aagaagatat gatgaactta ttgatggaag gtataagaag tataagaaat
     2581 gtgagagcag aaatgaatgt accaccttct aaaaaagcta aattgataat aatcccaagt
     2641 gaagaaaaaa tagaagctat tgagcttggc aaagattatt ttataacttt agcatctgct
     2701 tcaaatgtag agatagcaaa agataaatct aatgttccag aagatgcagt tggagtagtt
     2761 attgatggag ttgaaatatt tatacctctt aatgaattag ttgattttga aaaagaaatt
     2821 gagagattat ctaaagaaaa gaaaaagtta gaaggagaaa taaagagagt taatggaaag
     2881 cttgcaaatc aaggtttctt agcaaaagct cctgaaagtt taattgaaga agaaaaagca
     2941 aaaaaagaaa agtttgaaga gatgattaaa tctgttgagg aaagattaac aaatttagaa
     3001 tctaaaataa aataaatata agaagaaata aaacatacaa aaagtatata ttctatactt
     3061 tttgtatgtt tttctttata tatatacaaa tatgatgtta taattcttta cagatgtgtt
     3121 atatttttat tttctgttat gaatatatga attttatatc ttaaaattta taagcaataa
     3181 aaatttgata tattatgatg tttaatatag ggtaataaat acatattata tttattttac
     3241 tgtatttttt tacataatat ctctagaaaa gtataggaat ttatcgtaat ttaagtttaa
     3301 atattaaaga gaatttctat aggtagttta atcgacaatt taaatttata aagaaattta
     3361 aatttgaaag ctagtaagta cagtttggaa attgaaataa agtaaactaa atgatatttt
     3421 agatttggag gtgatattat gttcagggta gttatatgtg atgacgaaaa aatacaaaga
     3481 agcatactaa aagagtttac agaaaaactt ttgtctgaaa gatgtctaaa ttatcaaata
     3541 ctggaatttt cctgtgggga agatttaata tccaaatacc cagaaaaaat tgatattata
     3601 tttttagata tccaaatgaa agatatcaat ggaattgagg tggctaaaaa aataagaaag
     3661 tttgatgaaa aagtagaaat tatatttaca acagcttttt cagagtatgc tccccagggt
     3721 tatgaggttc gtgcttatag atatttagta aagcctatag agtatagtaa ctttgcaatg
     3781 ggtgtaaatc tttgtattga taaccttcaa agaaagaaga agcgttatat agttttaaat
     3841 agtaaaaaag gatttaatag aatactgata gattctattt tatatgttga aactgtaaag
     3901 agagatttag ttgtacatac aataggtaga gattataaag ctaatatgag catgaaacaa
     3961 gcagagaaat tactgtgtga aaatggcttt tttagatgtc atacaagttt tattgttaat
     4021 ttaagaagaa tagaagatct tagggataat atgattacta ttaatgaaca atttatacct
     4081 ataagtaagt atagacttaa agatttaaaa gtagcattaa caagcttgtt atgtgatata
     4141 atgtattaat tttaaaaagg taagtgaaaa tatcgtaaaa aatatttaat gtcatcacag
     4201 ggctattgat taaaactgtc ttaatatata aaagattatt tatattaaga cagttttatt
     4261 atgtaaaata gtagtttata gacttttaat attgtttaat atgtatatgt agaaattaca
     4321 ttatagtagc ttgattatta atatgctatg attgattttt atttatagta tatgcctttt
     4381 tcgaatatgc ttactttttt aaatttatga ctatttataa agctatatag atatttgttt
     4441 cattttacta tgtatacttt aattaattat attaatattt aaggaagtac aatataaata
     4501 ttaaagtgat atcttatagt ttattaaact tatagtagtg gactaataaa tagtttaatt
     4561 ctatgaaaag atttcctttt atgcaattta tttattgaaa tatgatataa tatatgaagg
     4621 tataagtatt agttgttaag ataatattta tattagtttt tatgtatact tagtgcaagt
     4681 ttttcatata ttgattaaaa ttgatggtga tttattattt ttagtatttt ttcgcctttt
     4741 gattcatact ttgtagaatg gtgtattttg taaaactgat tataagacaa gtttattcaa
     4801 attagcattt ttatagcata taaatgattg ttccccctaa ataagactta gatatatagt
     4861 attaaaatca aaaagtataa aataaaattg atgcttaatc atagataaat attaataaaa
     4921 tatacaaggg gattgtctaa taaaaaagat aatctccttt tttacaaata attctaaatt
     4981 gtgatataaa tctaaaaatt ttatcttaac atttaaccat ttaatgataa
//
LOCUS       DAMKOJ010000150         5024 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000150 DAMKOJ010000000
VERSION     DAMKOJ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.159"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            283..3117
                     /locus_tag="PC592_003451"
     CDS             283..3117
                     /locus_tag="PC592_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF4057377.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKIGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKIPGKPILFLHASIIENLIGRTLNSNEFSINNCNELLKSSKN
                     DTEDIFSTLLGYDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIRVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSEIDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     STYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     AIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEISYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNNKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     LTIIELIDEELKSKFKLGYILHCSFMIERCFKNTTFPYNNITEIISKNHELYSLIREA
                     FKPTEAYFNIFIPDEEIAYIIDMINEYLNK"
     gene            3160..4404
                     /locus_tag="PC592_003452"
     CDS             3160..4404
                     /locus_tag="PC592_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF4057378.1"
                     /translation="MEDEILKGKIKQLTILTLIFIFITPGFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAIDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAALAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENISTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMIPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSASLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKIKVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVNVKSESNIGCIPLKDK
                     IKIRVAKINRKLDVKNSVCFKV"
     gene            complement(4861..>5024)
                     /locus_tag="PC592_003453"
     CDS             complement(4861..>5024)
                     /locus_tag="PC592_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057379.1"
                     /translation="NVSVLVKAGAVSETTATDSVANATFEVKKHVAAPISTIGKISSG
                     LSSLFNILR"
BASE COUNT         1954 a          653 c          750 g         1667 t
ORIGIN      
        1 aattatatca accatatatt aataaatgat attacataaa ttgaaatata ttgaaaaact
       61 taaatttagt tatgtaacaa cataatactc taatttaatc tataaaaatc tatacctaat
      121 ataatgcaac tcttatttta acaccatcta ttacacaaaa caacatatta aaaagtaaaa
      181 tacaaaatat ccactataaa ccttatttta atactaaata tatattataa tgtatttaat
      241 atagcttaaa tatattttaa acataaagaa aggagacgat atatgctaag aaaagataaa
      301 gttctattat cactacataa attatgtgaa aatatgactt taaaagacct tcagtcagat
      361 aaaataggat tcactacaat agaaattgct aaccattcat ctcttgatag aagtaatacc
      421 agtaaagaat taaataacct gtataatgaa aaaaaagttc tgaaaatacc tggtaagcca
      481 attttatttc tacatgctag tattatagaa aatttaattg gacgtacttt gaacagtaat
      541 gaattttcta taaataattg taatgaacta cttaaatcaa gtaaaaatga cacagaagat
      601 attttttcaa cattacttgg atatgattct agtcttaaac tacctataga aaaagctaaa
      661 tctgctatac tctatcctcc aaaaggtctt aatacattac tcatagggcc tactggtgtt
      721 ggaaaaagta catttgctga aacaatgtac aaatatgctg tagaaagtaa aatcttttct
      781 tctgaaagca aattcgtagt atttaactgt gctgaatatg cagaaaatgc taacttatta
      841 ttaagtaact tatttggtta tgtcaaaggt tcttttactg gtgctaataa ggataaattc
      901 ggcatagttg cacaggctga tggaggaata ttattcttag atgaaataca cagattacca
      961 ccagaaggtc aagagatgct ttttcttttg atggacaaag gcatatacag acgattagga
     1021 gaatctgaca ttgtacacaa agctaatgtc tttattgtgt gtgccacaac agaagatata
     1081 cattcttctc tccttgggac ttttctaaga agaatccctg ttacaattaa cctacccgct
     1141 ttacaggata ggtccttaaa agaaagatta tctcttatta aatacttctt tattatagag
     1201 tcaaaatata ccaacgcaac tataagagtt cacaaagatg taattaaatc attactcctt
     1261 tacgattgtt ttggtaatat aggtcagctt aaatctgaca tacagcttat gagtgcaaga
     1321 gcctttttaa attacaagac tggacttaag gataatatag aaatagattt atcccttgtt
     1381 cctgattaca tctatattgg tcttttaaaa ttgaatgaaa atcgtagtaa tttaaataaa
     1441 ttatcagaaa ttgattatat gcttttttat gaatttaatg gtaacaactt agaagttgaa
     1501 tatacaaaag aactatctaa atacaatata gatacatcaa acaatggatt taaatactct
     1561 acagagattc cttatctgga aaatgatata aggagcatgt ttataaatta catggaaaaa
     1621 tactctacaa aattactttc gatatcttca gtaactcatt ctgattatac aagtaatgaa
     1681 atttttaaag taatcaatcc aaagatttac tatgctgttg aacattcttt aaaagaggct
     1741 gaaaaaatat cgagaaacaa atatacaaaa caaacttata ttgctctttc aatgcatata
     1801 agtgcactta tagaaaatat aaatcaagac acatataatc ctaagtacaa tttatataat
     1861 gataaaattt tcttagataa agatttaaat atagctaaaa tagttttaag tataattgaa
     1921 aacgacttac aaacatcttt acctaaagat gaagtaaaat ttatatccat gtttctaaat
     1981 agcacgtatc ttgaaccaaa caatcaatct gaaagtatag gggtcataat actcgctcat
     2041 ggaaattcaa cagcaagcag tatgtgtgat gtagcaaatt cattgcttgg tacaaaccat
     2101 tgtaatgcaa ttgacatgcc tcttgatgta aaagtaagta ctatacttga taaagctata
     2161 gaattggtaa aagaatgtga cgaaggtaag ggtgtacttc ttttaacaga tatgggctct
     2221 cttatagctt ttggagaact tatttcagaa aaaacaaaaa tcaaaactcg ctcaattgaa
     2281 atggtatcta ctccaatagt tttagaagca gtaagaaaaa gtacactacc agaaatgact
     2341 ttggatgaat tagctaattc cttaagctct ttaaatccat atattggacg agcagcaatt
     2401 gattcaacag aaataagcta tcctgaaaag tcaagagagt atgtaataat aacgacttgt
     2461 ataacaggat atggttcagc tatgaaagta gcagacttta taaattcttc acttaagaat
     2521 attagtaaat acaatattaa tttagttcct cataatatag aaagttttaa aatgtataag
     2581 aacaaattta gtaataataa aattctggca gttgttggaa gtgtagattt taatgtagcc
     2641 aacacccctt ttatacacat agaagaacta ctaaatggat atggcctaga tatgctaaac
     2701 aaaataatag agggtacatt caatgccaat agtattacca atataaaaga aacaaatcta
     2761 tcatataaca gcttaataat aaactttatg acccaaaact tagagctttt ggactctgtt
     2821 aaattattca actatgtcaa ttcttcctta cttacaataa tagaattaat agatgaagaa
     2881 ttaaagagca aatttaagct aggatatata ctacattgct cttttatgat agaaagatgt
     2941 tttaaaaata caacttttcc atataataac attactgaaa taattagtaa aaatcatgaa
     3001 ctatatagtt taatacgtga agcctttaag ccaacagaag cttattttaa tatttttata
     3061 ccagacgaag aaattgctta tataatagac atgattaatg aatatctaaa taaataaaac
     3121 ttatagcact tattttgtgc atgttaatta atatatgaaa tggaggatga gattttgaaa
     3181 ggaaaaataa aacagttaac aatacttaca ttaattttta tatttataac tcctggattt
     3241 gcatttgcag atactccacc agtaccaaac tcttcaagag cagcactact tatagaccag
     3301 gaaactaaaa gaatattatt tgaaaaaaac attgatgaga aaatgccatt agcgagttta
     3361 agtaaaatga tgaccttttt attggcaata gaagcaattg ataagaatca agtaaaagag
     3421 actgatatgg tgaaaataga caagtctaca gcttcagtag gaggttctac ttgtaaactt
     3481 aaagatggtg atgaaatatc tctaggagaa cttatgcagg gtctcatgct agtatctgga
     3541 aatgatgctg ctctagccat agctaagcat attggtaaaa ctgaaaagaa ttttgtaaat
     3601 atgatgaaca agaaagcaga agaaatagga atgattgata cgtattattt taatccaaat
     3661 gggcttccta tatatactga cccagagcat aaagagcctc ctattgagaa tatatcaaca
     3721 gctcacgata tagttacact tggaaagtat atgtatgacc attatgaaaa ccaagttaca
     3781 agaataacca ctatgcaagt atataatgat actaaaaaag attttacaca ttataacaca
     3841 aatcctctac ttgtttcagt acctggtgtt gatggaataa agacaggcta cacagataat
     3901 gctggatatt gtcttgcatt ttctatgatg atacctaagg atgctaaaaa cgaaagaaat
     3961 catagattaa taggtgttgt acttggtgat ggtaacaaga aaaatagaat ttcttcttct
     4021 gctagtctat tgaagtatgg taaagataat ttccattcta aaaagatagc acataagggg
     4081 gatattatag agactccttg tgttgatggt attgatgatt ttaagataaa agttaaggtt
     4141 gataaagatt tgtatggtgt tgtttcagat aacgagaata tcaatccgaa ggtagtattt
     4201 aaaaatatga attatcctat ccataaagga gatattgttg gtgttgcaaa gtattataat
     4261 gattctggta aatttgttgg aagtgtcaat gtaaaaagtg aaagtaatat aggatgtatt
     4321 cctttgaaag ataagattaa gattagggtt gctaagataa atagaaagct tgatgttaaa
     4381 aattctgttt gttttaaagt atagtaaggc atactattaa aaaagtgtgt taaatttata
     4441 agactccact ttgtggagtt tttttgtttt ttacaaaaaa ttaaaatagt ggcaacaatt
     4501 gaggatgtga gggagagttg ccactatttt gtatagggta ttatattatg tttttaagct
     4561 agttttacta tcttctatgt ttatataata actcttgtgt gtgaatttaa tagataattc
     4621 atatgaaaat tatgtgaagt tttgggtttt taaataaatt tttatttaaa taatacacat
     4681 aaatatttca atactctaag ttttaaaata ctatagagta gcagatttta tttaaaaaat
     4741 ttgctactct tggatattaa aaagctgtag gaaaattatt ttaaaaatcc tacagctaat
     4801 attagtatat acaagaagat ttactttttt tgaaactagt ttttaattat gcttaattat
     4861 ttatctcaag atgttaaata aacttgatag tccagaagat atttttccta ttgttgatat
     4921 tggagctgcc acatgttttt taacttcaaa tgttgcattt gctactgaat ctgtagcagt
     4981 tgtttcagat actgctcctg ctttaactaa cacacttaca ttat
//
LOCUS       DAMKOJ010000151         5019 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000151 DAMKOJ010000000
VERSION     DAMKOJ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5019
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.160"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            36..932
                     /locus_tag="PC592_003454"
                     /pseudo
     CDS             36..932
                     /locus_tag="PC592_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
     gene            1334..3238
                     /locus_tag="PC592_003455"
     CDS             1334..3238
                     /locus_tag="PC592_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF4057380.1"
                     /translation="MKIKFIIVVSIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LVSYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLLRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNDIPLVSANVYEQSGEN
                     YVNPYVMKNINTDKGVVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKI
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNIKEMTKWAKEW
                     QYNENKGIHKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEENLSSSSLSKNSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
     gene            3603..4382
                     /locus_tag="PC592_003456"
     CDS             3603..4382
                     /locus_tag="PC592_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF4057381.1"
                     /translation="MSYKNIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKVFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIINISSQASFQPLPYQNIYSSTKAFVRNY
                     TRALNVELKSKGINAITVCPGWMSTNLFKRGIVVTEKGTKHFPGIVSPDVVAKKALKD
                     TKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         2056 a          518 c          880 g         1565 t
ORIGIN      
        1 caggaaccct gtgactttag tcatgggagg ttcagaagga agtaagtata gttgctactg
       61 cagatttaca ttcacatttt tctgataaat taacagtcga ccttgttaat gaacgaagca
      121 acccaattga acctgttgta gtagatgcag gtgatttctt agaccctcaa acagatgaaa
      181 tgactcaatg gtataaagag tggaaaaata taagagataa taatagtggt aaaacgatta
      241 gtagatgccc aatggtcatg gatatgaatc agggaatgta tgatgcagta gtacttggaa
      301 atcatgagtt tgtatctgaa aaagatgagt tttggtcaga tgagcgtctt ttagatgctg
      361 ttatagagga ttttgaacag gtgacaattt ctgtgttatc agcaaatata tataagcaat
      421 ctggtaaaaa ttatgttaaa ccatatatta taaaagatgt agagacgagt gaaggtaatg
      481 taaaagtagg aatattaggg cttactataa aagaagtagg taaaggtctt gaaaatgtaa
      541 atttacaaga gcaatttcaa tataagggga aattgtatgc aaatgattta gtagaagatg
      601 caaagaaatg ggtaaaaatt atgaaaaaga aaaaaccaga tataatagtt gcagttgtac
      661 attcaggaga agagcctaaa aatccaaaac atccaggaaa tagaataaag gagctagcaa
      721 ctacagtaga tggtattgat gcgattgttg ctagtcatac tcatgaaaaa atagatgaac
      781 atgaatataa aaataagtct ggagagaaag ttatagtgac acaaccaggt gagcatggta
      841 aatattattc taaaattact tttaaagtaa ataaagaaaa gggttcatgg attattaatg
      901 ataaattcag taaaacaatc gaggttgaat aactttataa aatctataga taaaataaat
      961 tatctgatat tgacataata tacaagataa agtttccaat attagtacag agcataaggt
     1021 aaaatattct aataataaga gaataaacaa gataaataaa aatatttcaa catataatat
     1081 atagtatgaa catattatac tactccttac tttataattt gaacatgtta gaataagtct
     1141 tacttgacaa ttttagtgta ttagagtaag tattattttg ccaataaaaa acattgagaa
     1201 ctatatgtag atttgcttaa aaaggaattt acatatagtt cttttcgtat aataaatagt
     1261 acaatcttat gtggtaaaga taacgcgtga tattaaattt tattatcatc caaaatctaa
     1321 ggaggagtct tttatgaaaa taaaatttat tatagtagta tcaataatat ttttaatagt
     1381 attacttgta gggtgtcaaa gtactaaaga tacagaaata aatgtactcg ctacaagtga
     1441 tttacattca attattccag ataatttagt ctcttatgta gaggaagaga gaaaatatga
     1501 tgagaatcta cttatggtag acgcaggaga tttttttgac atgcaaagtg gtgagatgaa
     1561 caagtggttt actggtcaaa aactattaag atttaaagat gggataccag agtacaaaaa
     1621 aatagccgaa ccacgtgaag gtgaagttcc attagctaaa aaaatggcaa agctgaaata
     1681 tgatgcagtt acatttggga atcatgaatt tgtatctaat gacaagcaga gccttgataa
     1741 attagtttct gattttaaaa ataacgatat accattagta tcagcaaacg tatatgaaca
     1801 atctggggaa aactatgtaa atccatatgt aatgaaaaat ataaatactg acaagggagt
     1861 tgtaaaggtt ggtatacttg gtttgactat aaaagaagta ggggaacgtt caaggtttaa
     1921 aagttttgaa caagataaaa aggctagaga acttggggag caacctcaat acaaagggaa
     1981 attatatgcg aatgatttgg tagaagatgc aaataagtgg gtaaaggtta tggaaaaaaa
     2041 agaaaagcca gatataatag ttgctattgt acattcaggt gaagagccaa aaaatcctaa
     2101 aaatccagga aatagaataa aagaacttgc aactactgta gaggggatag atgctattgt
     2161 agcaggtcat acacatgaaa aaatagaaca gcatacatat aaaaataatt ctggtgaaga
     2221 agtaatagta acacagcctg gagctcatgg taatagtata tcaaagatta attttaagtt
     2281 ggataagaag aatgataagt ggtttataaa agataaatat agtgaattaa aaatttttgg
     2341 aaaggaagta aatataatta caacctctgg tctgaatcca aaattttcag atgaaatggc
     2401 agttaatttg tttaatgaaa gagataggga tgttcaacct atatttatag atactggaga
     2461 ttttttaaat actaatataa aagaaatgac taaatgggct aaagagtggc aatacaatga
     2521 aaataaaggt atacataaaa aaataaatga atggccaatt gtatatcttg gttatgatgc
     2581 tgtagtactt ggtagtcatg aatttacaga agataaagag acttttgagg aaaaaaaatc
     2641 tactttggat tatattatag aaaactttga agaaatgaag ataccagtat tatcagctaa
     2701 tatatatgat gaatctggag aaaattatgt aaaaccttat ataattcata atgtagaaac
     2761 tagggaagga aatataaagg ttggagtatt aggtcttact actactgata aggatgaaga
     2821 aaacttaagt agctcaagct taagcaaaaa ctcaaagact tcgaaaattc ctgaagaaac
     2881 aggaaagtta tataccaaca atctagtaaa agatgcaagc gaatgggtaa aagttatgca
     2941 aaaggaaagt cctgatgtga ttgttgcagt tgtacattca gataataata gtactctaaa
     3001 aaatccaagt agtgaagtaa aaaaacttgc aatgtcagta gatggaatag atgctattgt
     3061 tgtaggtcat acgaaaaata aggtagaaga acatatttac aagaataagt ctggggatga
     3121 ggtcatagta acacaatctg gagaagattg ttattcaaaa ataagtcttg aactaagaaa
     3181 agaaaatggc aagtggaata tcataaacaa atatagtaaa gcaataaaaa tgaagtgaat
     3241 ttattgatat ataaaccatt attaacactg atttttataa tatttaacac tactttttat
     3301 actataatta acactgattc tataatatca ttaacattac ttttatacta taattaacac
     3361 tgattctata gtattattaa cactactttt tatactataa ttaacactga ttctataata
     3421 tcattaatat tacttttata ctataattaa cactgattct ataatattat taacattact
     3481 tcttatgcta tataacaatt attgaaaatg atatgaatat aacatctgaa tagagggtgt
     3541 tttatttgta aaaaataagt ttacagtttg agcgtataaa cttatggtaa aggagaataa
     3601 ttatgagtta taagaatatt gcaattataa caggtgctaa tagtggtttt ggtaaagagt
     3661 ttctaaaatt attaataaat gaagaagaaa taacagaaat atgggcagtt gcaagaaaca
     3721 aggcgagatt aaatcaatta gtagatgaat ttggaagtaa ggtaaaagtt ttttcaaaag
     3781 acttatcaaa gatagaagaa gtaaaagaaa ttggtacatt tttaagtaaa gaaaatgtat
     3841 gtataaaata ccttataaat aatgctggtt ttgcaaagtt ctgttcatac aatgatttaa
     3901 gtatagatga atctattaat atgattgatt taaatattag tgctgttgta gcattggggc
     3961 ttatatgtat tccatatatg caaaagggaa gtcatatcat aaatatttct tcacaagcat
     4021 cattccaacc attgccatac caaaatattt atagttcaac taaagcattt gtaagaaatt
     4081 atacaagagc attaaatgtt gagcttaaaa gtaaagggat aaatgcaatt actgtatgcc
     4141 caggttggat gagtacaaat ctatttaaga gaggtatagt tgtaactgaa aaaggaacaa
     4201 aacatttccc aggcatagtg tctccagacg ttgttgctaa aaaagcattg aaggacacaa
     4261 agaagaataa ggatatttct gtatatggta taaatacaaa atccagtcat ttactagcaa
     4321 aactattgcc acaaaagatg atgatgaagg tttggttaat gcaacaacat attaaggaat
     4381 aagagttttg gtaattaagt atcagttaga gattcaatct gttacaaatt atgagaattt
     4441 ttgttgagta aataataatt gtgacaaaac ggcttatcta gtgctgataa gccgtctaca
     4501 atgtatataa aatatatttt taatttcaaa gttattacac caccttctta aaatattaga
     4561 ttatataaat aatctacaat cacaactgat taacaaaatt atgagttaat aaattatatc
     4621 acatgcaaat atgaaagaat agtatgaaat ttttataaac atatattaaa tgtttctcaa
     4681 tgaaattgac tttgtatatg aactgaatga cttattcaat atggataaga catttttctt
     4741 gtaataagat atgattgtcc tataaggttt atgtaatttt gatataatat attgattaac
     4801 agcatacatg ttattggtga acatatttct atagaatgga atatataatt ttttatattt
     4861 atcattgtat cattgtctaa agaaagttaa aaagagtaga gcacaaagga attatttgta
     4921 ctttactctt ttattgtttt gttaaaaata ctaatttata ttagtgatta aaatatattt
     4981 aactagagta taaggatagt atataatctt ataattgat
//
LOCUS       DAMKOJ010000152         4971 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.161, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000152 DAMKOJ010000000
VERSION     DAMKOJ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4971
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.161"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(133..4299)
                     /locus_tag="PC592_003457"
     CDS             complement(133..4299)
                     /locus_tag="PC592_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF4057382.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANVPVVLQDIATGVRLTVL
                     TNASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFAAAIVGPVPIAEIPPISSVINPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIQNILDSCVSVSNINLIIDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNFLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEIGTVINSQNNNQLTVEFFS
                     EGESVIGNDYAIDDVSLREITVPTFTPIKTSNTETANIGDIVTYTVTLDNTCNSPLTN
                     VFFRDIIPNGLKFIPGTVTVDGISVPGVDPNIGFQLPDIGGGTRIEVTFNVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNNFSVDSNPVPVEVISADIEVTKLSEPSIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPDSIINSEYSLDGGVSFQPWNGSLNIGTLELGATR
                     VIIIRGIVNPTTVGIIRNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVANLGPANAENVILNDDIPDVILNPEYSLDGGVSFQPWNGSLNIGA
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVANEDVAVPGEEFVYTIEIFNEGPSNAMNVVLTDNIPDVILNPEYSLDGGASFQPWN
                     GSLNIGTVAPGQLIRIIIRGLVSSTATGNITNTAEVSAEVPEPVTDSSTVITPVVASA
                     DIEVIKTSNMDTAVPGEIFSYTITVTNLGPSAAQSIVLTDDIPDIILNPEYSLDGGVS
                     FQPWNGNLNIGTLDTGEIRSIIIRGTINQTSVGTIINTATVSSTTPDPNPDNNTSTVE
                     TDISPLADISVIKGNEPLAIQGERFIYGIEIVNAGPSFSENIVLTDNIPASILNPEYS
                     IDNGVTFQPWTGSLNIGTLDAGEIRNVIIRGTVSQTAVGTIINTATVSSTTPDPNLNN
                     NTSTSEAEVSSSADISVVKRSNQNVVVPGDVLNYTIEVRNAGPSTAQNVTLTDNISAS
                     ILSPEYSIDNGVTFQPWTGSLSIGTLYAGEIRNIIIRGIASETAIGTIINTATVSSTT
                     PDPNPNNNTSTSEIDISSSADISIIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKTVFSLDRGVSFQPWTGSINIGILPAGTLRVILLRGLIKSTCLDKLTNI
                     AEVTSTTPDSDLNNNISRVQVEIKQCCSNDCCCNCCCNNCCNCFFNDCCNDCGYKDCC
                     CNCCKNDFWC"
BASE COUNT         1509 a          825 c          724 g         1913 t
ORIGIN      
        1 ttttaataac tagtattacg aatgtggtcc atatcgaaaa tagaaaactt attaatattt
       61 aaaaaatatt ttactcatat atgaattttt tatttcagtt taatttaaga tatacaaaat
      121 tattgtataa aatcaacacc aaaagtcatt tttacaacaa ttacaacaac aatccttgta
      181 accacaatca ttacaacaat cattaaaaaa acaattacaa cagttattac aacaacaatt
      241 acaacagcaa tcgttagaac aacattgttt tatttctact tgcactcttg atatattatt
      301 gttaaggtct gaatctggtg ttgttgaagt aacttctgca atatttgtta atttatcaag
      361 acatgttgat tttataagtc ctcttaatag aataactctt aaagttccag ctggtagtat
      421 acctatatta atacttccag tccaaggttg gaaacttaca cctctatcaa gtgaaaatac
      481 tgttttctta agcttatctg aaacattgtc tattaaagta acattttgag cattttctgg
      541 tcctgcattt gatactacta ttacaaaatc tatttgttct cctacacatg cttctgtttt
      601 atttgctaat tttattatag aaatatctgc tgatgaactt atatctattt ctgatgttga
      661 agtgttatta tttggatttg ggtcaggtgt agttgaactt actgttgctg tatttataat
      721 tgtacctatt gctgtttcac ttgctattcc ccttattata atatttctta tctctccagc
      781 atacaaagtg cctatactaa gacttccagt ccatggttgg aaagtcactc cattatctat
      841 tgaatattct ggacttaaaa tagaagctga tatattatct gttaaagtta cattctgagc
      901 agtagatggt cctgcatttc tcacctcaat tgtatagttt agtacatctc ctggtacaac
      961 aacattctga ttgcttcgtt ttactacaga aatatctgct gatgaactta cctctgcttc
     1021 tgatgttgaa gtattgttat ttagatttgg gtcaggtgta gtcgaactta ctgttgctgt
     1081 atttataatt gttcctactg ctgtttgact tactgttccc cttattatga catttcttat
     1141 ctctccagca tctaaagtac ctatattaag gcttccagtc catggttgga aagtcactcc
     1201 attgtctatt gagtactctg gatttaaaat agaagctggt atattgtctg tcaagactat
     1261 attttctgaa aaagatggtc ctgcatttac aatttcaatt ccataaataa atctttcacc
     1321 ttgtatagca agtggttcgt tgccttttat cacagaaata tctgctaatg gacttatatc
     1381 tgtttccact gttgaagtat tattatctgg atttgggtca ggtgtagttg aacttactgt
     1441 tgctgtattt ataattgtgc ctactgatgt ttggtttatt gttcctctta ttataatact
     1501 tcttatttcc cctgtatcca aagtgcctat attaagattt ccattccatg gttgaaagct
     1561 tactcctcca tctaatgaat actctggatt taaaataata tctggtatat catctgtcaa
     1621 aacgatactc tgagcagcag atggacctaa atttgtaaca gttatagtat aactaaaaat
     1681 ttctcctgga actgctgtat ccatattgct agtttttatt acttctatat ctgctgatgc
     1741 aactacagga gttattactg ttgatgaatc agtaactggt tctggtacct ctgcacttac
     1801 ttctgctgta ttagtaatat tccctgtagc agttgaactt actaatcccc ttatgataat
     1861 tcttattaat tgccctggtg caactgtacc tatattaaga cttccattcc atggttggaa
     1921 acttgcgcct ccatccaatg aatattctgg atttaaaata acatctggta tattatctgt
     1981 taaaactaca ttcatagcat tagatggtcc ttcattaaaa atttcaattg tatatacaaa
     2041 ctcttctcct ggaacagcta catcctcatt agccactttt ataatagaaa tacctgcctg
     2101 tggattaact ggcgtgataa tagtagatat attgttgctt aaatctgggt caggtgtagt
     2161 tgaggaaact gttgctgtat ttactatata ttctgaagaa tttaaactaa ctgttccttg
     2221 tattaaaact gtcaatgaaa ttccagagtt taaagctcct atattaagac ttccattcca
     2281 tggttgaaaa cttactcctc catccagtga atattctgga tttaaaataa catctggtat
     2341 atcatcattt aatattacat tctcagcatt tgctggtcct aagtttgcta cttgaatagt
     2401 atatcttaat aaagtacctg gaacagctga attaggttct gctgttttca ttaccaaaat
     2461 atctgccaat aaattcactt ctgtctctat tgtagatgta ttattattaa gatttgggtc
     2521 tgctgtagtt gaagatacta cagctgtatt tcttataatt cctactgttg ttggatttac
     2581 aataccccta attataataa ctcttgtcgc tcctaattct aatgtcccta tatttaaact
     2641 tccattccat ggttgaaaac ttactcctcc atccaatgaa tattctgaat ttataataga
     2701 gtctggtaca tcatctgtta aaaccacatt ttcagatggg aatggtccgt tatttactac
     2761 ttttatagtg tatattaatt cctctcctgg attcactata gaaggttcag ataattttgt
     2821 aacttcaata tctgctgaga ttacttcaac aggaactgga ttagaatcta ctgaaaaatt
     2881 atttggtata ccaccttcta caggagtata ggagtaatct atagtagcta tattattagt
     2941 aggatttggg ttaggaatac tctcaactac aacattaaaa gttacttcaa tccttgttcc
     3001 tcctccgata tctggaagtt ggaaacctat attagggtct actcctggta cagatattcc
     3061 atcaaccgtt acagttccag gtataaattt taaaccgttt ggaattatgt ccctaaaaaa
     3121 tacgttagtt aaagggctat tacaagtatt atctagtgta actgtatatg tgactatatc
     3181 gcctatgtta gcagtttctg tgttacttgt ttttattgga gtaaaagttg gaacagtaat
     3241 ttctcttaag gaaacgtcat ctatagcgta gtcatttcca ataacacttt ctccctcgct
     3301 aaaaaattct actgtaagtt gattattatt ttgagaatta attacagtac ctatttcttt
     3361 ccactctggt gcatttgtat taactggaat ttgagctcct aatgttgctt gatatagtat
     3421 attattattt tggtcaaata ttcttacacc tagctgtggt ggtggatatc ctgttacctt
     3481 aaaaaggttt aaaatccaag tactaaataa aaaattagtg ttaggtgtaa cttgtactgt
     3541 tgatttaaaa aatacagctc caggattaaa accatttacc accatcattc ttcctgtttc
     3601 atttcctgta gtatggtcag caatacgcca ccaagctcct ataacattac tcattgcatt
     3661 tgtcataata ttttgtactg tatattctcc atctaaaggt gtaaacttag ttgggtctgg
     3721 tacaacatac gtaaaatctg gtgtcacatt tgggtaaggt tctatctcag gccctgtatt
     3781 acttggtgtg cctggtggga agaaaccgaa tgttccatta tctgcgtcta taataaggtt
     3841 tatattagat acagatacac aagaatccaa tatattctgt ataggtgtat aaatcacagg
     3901 accatttaat atattttgat ttgttatatc tgaacctgct actgttatta atagtgtgtt
     3961 gggtgttgta ccatctaagt ttgttgaacc aataggagga tttatcacag aactaatagg
     4021 tggtatttct gcaattggaa ctggacctac tatcgctgct gcaaaattcc ctggtgttgg
     4081 tactcctcct gtagttccaa aagcttctac aattctatag ttaccatttg gaacgttagt
     4141 aaaaacataa tttcctgatg catttgtgag aactgtgagt ctgactccag ttgctatgtc
     4201 ttgtaataca actgggacat tggctattcc agaatctcca gaatcaatgg tagcacttct
     4261 gtttctatca aaaactattt gtcctgatac tgttgccata ttatcactcc tttgagatta
     4321 taaaaatttg tgttcataat atattattct ttaaaattct tttatgtgac attttaagcc
     4381 tataagtgca ctttttttct ataatagcta acatctattt ttgctgtttg aaatatcgat
     4441 atcggttttt taatatttta ttatatatgt aaagaaagta tattgtatta taacttaaaa
     4501 attatcaaat aatagcaaat ggcataaaat gtattatttt atgccatttt ttaataatca
     4561 agtattttca ataaatacat aattataaaa ctgtattttg tcagtgaaat gtcagtgatt
     4621 tttttgttat tttttacttt tttattttga acaaatttaa aaaaggcttt tatattacaa
     4681 atcaccaaac aaaatatcat aaattttaga cttaattact taagacattc tgagatataa
     4741 ctttctgtat tttatttttg tctaattggg tttagagagt ttatttttct caaaaataac
     4801 aagcttttat attggttttt aaataggttt aaatttttac tacgatagtt tgtacctttc
     4861 taatcaaatc gagcttaaaa tctacttaaa tgcataattt ggtactttta cctaaaacta
     4921 ataattttaa ttaacattat ttttattatg taaactaaaa gaatttttct t
//
LOCUS       DAMKOJ010000153         4969 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.162, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000153 DAMKOJ010000000
VERSION     DAMKOJ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4969
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.162"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(486..2621)
                     /gene="rnr"
                     /locus_tag="PC592_003458"
     CDS             complement(486..2621)
                     /gene="rnr"
                     /locus_tag="PC592_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDF4057383.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIISPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLS
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEVLARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYVYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3222..3836
                     /locus_tag="PC592_003459"
     CDS             3222..3836
                     /locus_tag="PC592_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF4057384.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     LGNALRDISKKYPDLIKKELDSWDISNKKVEFVYKLASKRILAK"
     gene            3854..4216
                     /locus_tag="PC592_003460"
     CDS             3854..4216
                     /locus_tag="PC592_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057385.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYKGYPLKVEYSLTPIRGKQILDALAIMQDIGIN
                     FMLDNGMEDILKEKGVLK"
     gene            4322..4819
                     /locus_tag="PC592_003461"
     CDS             4322..4819
                     /locus_tag="PC592_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF4057386.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELKENESVTATDFVQGTTSWHGKLGG
                     LDRLDASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1610 a          768 c          609 g         1982 t
ORIGIN      
        1 cttatttttc agttatacat ttctattaaa tgcttcttaa tttcttattt ttcagctagc
       61 tatttctact aaatgtttct tagttgctta tttttcagtt atacatttct attaaatgct
      121 tcttaatttc ttatttttca gctagctatt tctactaaat gcttcttaat ttcttatttt
      181 tcagttagcc atttctatta aatatttctt aatttcttat ttctcagtta gctatttcta
      241 ttaaatgctt cttaatttct tatttttcag ctagctattt ctactaaatg cttcttagtt
      301 tcttatttct catttatcta tttctattaa atacctctta atttcttatc tttcagttgg
      361 ctacttccat gtaaacattt cttaattacc tgtttttata atttatttta tcgagtattg
      421 tgcactatat atttatccat atcacaaaca ccacaatttg ttatctctta ttttagctgt
      481 tttatctact cctctatctt ttcaactatc tcaaagtcaa tttccttaaa atctacattc
      541 acactctcaa cctttatctt aacaaggtca cctatcttat atgacttctt agttctttct
      601 cctaaaacac tataagaact ctcatcataa acatagtaat catcattcat atttgcaagt
      661 cttatcaagc cttctatagt attatctaac tcaacaaata ttccaaatga agttacacta
      721 gatacaacac cctcaaattc ttgaccaact ttatccttca tataaagagc cttatagaaa
      781 tcatgtacat ccctttcagc taactctgcc tttctttctt tctcagacga ttgaacagat
      841 gcataatcca ctatagtagt aagctgttct tgtctttttc cgcttatttt attatttaaa
      901 gattctttta ttattctatg aatttgaagg tcaggatatc ttcttattgg tgaagtaaag
      961 tgacagtaga atttagctgc taatccaaag tgcccactac attctggtga gtacttagct
     1021 tgttttaaag aacgaagcat tatagtactg atagctcctt cttctttttt gccctttatt
     1081 ttctctatta taccttgtaa tgcttttgga tgtacttcct ctttatcacc ttttattata
     1141 tatccaaatg tagatataaa cttactcaat tcttccattt tttccaaaga tggtgtctca
     1201 tgtattctat acacaaatgg tattcccatc caataaaaat gttcagcaat tgtctcatta
     1261 cttataagca taaattcttc tattatctta ttagatattc ttctttcata tggttttata
     1321 tctacaactt caccttttcc atttaaaatt atctttgcct cagggaaatt aaagtctata
     1381 gcccctctct tttcccttct tgacataaga atcctagcta aaacttcagc atttttaaaa
     1441 tcttcaacaa catgttcaaa agtcttttta agtttttcat catctttctc taatatatca
     1501 gatacttctg tataggtcat tctagctttt gaatttatta cagattcaca tatttcatgt
     1561 ttaaccacat ttcctttatg gtctatttcc ataaatatag aaagggtcaa cttatcttca
     1621 aatggattta aactacatac tccatttgaa agagtctttg gcaacattgg gattacttta
     1681 tctactaaat aaactgatgt agctcttttt aaagcttctt tgtcaagttt atttttctct
     1741 cttacatagt gtgtaacgtc agctatgtga actcctagtt tgaagtttcc attagataat
     1801 acttctattg atatagcatc atctaagtct tttgcgtcat ctccatctat agtaaatata
     1861 tttaaatctc ttaaatctct tcttcttttt atctcttctt gaggaatctc aacagctaca
     1921 gcttctgctt cttgcaatac tttctttgga aattcttctg gaagaccatg ttctcttatt
     1981 atagaatcta tttctacgcc tctttcacct ttttgaccta gtatctctat aattttacct
     2041 tctggttttc tatcctcttg tggccatact gtaatttcac atactacttt atcattatct
     2101 actgctccac taaaatgttt tttagggata tatatgtcct tagtaaattt cttgttgtct
     2161 ggtgttacaa atccaaaagt tttacttgat tggaaagtac ctactattct agttatttct
     2221 ctctttatta cttttactat tcttccttca gctctctttt cttcagttgc aggtactact
     2281 atttctgcca taactctatc gttatgcata gcaccattta tattgtcact tgaaataaat
     2341 aaatcctgtg tgtattcaac atcagattct acaaatccaa aacctttttt gtgcgataca
     2401 aattttccaa caaagtatcc catttgattt ggagatatta tttttccttt tttagtaaag
     2461 cagatataac catcttcttc taattcattt aaaaaattat aaaacattgg catttctgat
     2521 gaatgtatat caaatatttc tgctaattct tcttttttta gaggattata tgcactttca
     2581 tttattaatc ctagcaaact ttctttaagt cctggtatca tttttccctc ctattttact
     2641 tttcattata ttattattta gattgtcttt tatatttttc agacaaaaca tgttttactt
     2701 atcacatagc tttctatatt ttttattatt gttacaagtt aaaattacat atttatattt
     2761 ttgatttaat gtaagcttta tcatactaat ttcaaacaaa ttatgatgat ttgtaaatta
     2821 taaattattt gtaaatatca ttataattac ttaaattatt ctttatcata attgcttaag
     2881 ttactcttta tcacctaatt atacactatc aaataagatt ggtaaaatat tcatctcata
     2941 taagtattac tatataataa tttattctat tagtatactc aaatcatgta aaatttatat
     3001 aactcaatta attttttaaa tacaacttta taatataaaa cttataataa aagtaaattt
     3061 atatgttaaa tgaggttgat tttttattat tttttattta tgctagtact aaagacttgc
     3121 aaacgttttt tgacaagtct ttattttgtc taaattaaac aaaccttttt acaaataaat
     3181 acataaaatt taaactaatc tacttattgg aggagataaa attggaagaa gtaattgcaa
     3241 aaattattac tatagaaaat ggctttaaag aaattgaaaa tattgctaaa aaaattgtga
     3301 aaaataatga ctcaaaaaag tgttattatc tatcaatcta cttatatagg tcagaatatt
     3361 atcaagtaag agaattagct gtgtttatac ttggttttat atcagtaact atttctgaag
     3421 ctttgttatt tttaaaagac aatgtgagta aagacgaaaa ctggagagta caagaaatat
     3481 tagctaaatc atttgattat tattgcagtg aagtaggata tgaaaaggca cttcctgtta
     3541 taaaagaatg gcttaattct gatagtccaa acataaaaag agctgtgaca gaaggtctta
     3601 gaatttggac tagtagagac tattttaaat ctaatcctga tgtcgctata tcactactct
     3661 ctagtttaaa agaagatgat agcgaatact tgagaaagtc tttaggtaat gctcttagag
     3721 atataagtaa aaaatatcca gatttaataa aaaaagaatt agattcatgg gatatatcaa
     3781 ataaaaaagt tgagtttgta tataagcttg cttcaaaacg tatcttggca aagtaaaatg
     3841 ggggtgaact tatttgaaac ttcgtgatga gtatacttgc ccattagaac taacacatga
     3901 tatgataaaa ggcaaatgga aatctattat attatggaga ttacgcatag gaccaacttc
     3961 cttatcaaaa cttgaaaagg aaattaatgg tattaatcaa aagatgttac ttgaacaact
     4021 taaagaatta attgaatttg gtcttgtaga taaaaagaca tataaaggtt acccacttaa
     4081 agttgaatac tcacttacac ctattcgagg gaaacaaata ttggatgctt tggctataat
     4141 gcaagatata ggaattaact ttatgttgga taatggtatg gaagatattc ttaaggaaaa
     4201 aggtgtttta aagtaaatag atacccacaa aaaagtaagt aatttaccat tattttcaac
     4261 tggtatataa ttgaattata gagatattct attaatttat tatattggga ggtaaattat
     4321 tatgaaagta actagtacag gtatagtaaa tggtgttata gaagataaat atggtaaaag
     4381 aggaactcag ttcaatgaag gtggtatgcc tacatattca ctacctctaa agtttgaaga
     4441 tgctccaaaa aatacagtat cctttgctgt gtttttagaa gataaagatt ctgttcctgt
     4501 gtgtgggttt gcatggatac actggttagc tgtaaatata acaaaagatg agttaaagga
     4561 aaatgaaagt gtaacagcca ctgattttgt acaagggact actagctggc atggtaaact
     4621 aggaggtctt gatagattgg atgccagtgt atatggtgga atggcacctc cagacagacc
     4681 tcatgtctat gaaatacatg tatttgcact tgataccatc cttgaccttg aaaaaggatt
     4741 ctatatgaat gaatttttca aagctattga aggacatgtt ttagatacat ttacactaaa
     4801 aggaagttat tctaattaat tagattgact atagctaatc attaattaag tgcctacatt
     4861 taattgatga ttagcttaat tgttattaga atatttttta catattatat taatttatat
     4921 tttaatttat tggtatttta atttccatta gattattatc aatttatat
//
LOCUS       DAMKOJ010000154         4622 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000154 DAMKOJ010000000
VERSION     DAMKOJ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4622
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.163"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            160..1083
                     /locus_tag="PC592_003462"
     CDS             160..1083
                     /locus_tag="PC592_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDF4057387.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTDLKKMKDICFSIEGNNEQGDLVIQNFIDSLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAITPLVEKNIENILDNGFTK
                     ALTGPVSRGDITPIMKHLSVLDKKDEEIYKILSLNLLKITALGNDNLLKCTKNITIEN
                     AVENLISKSEKYKKIYKLLGGKNDEKYYTDF"
     gene            1058..1885
                     /gene="panB"
                     /locus_tag="PC592_003463"
     CDS             1058..1885
                     /gene="panB"
                     /locus_tag="PC592_003463"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDF4057388.1"
                     /translation="MKNTILTFKNAKYEGKKLSMLTAYDYSMAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDTVKNAGR
                     LVKEGGAHAVKLEGGSNIIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKIQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMRDSIKNYILEVKTGAFPQEKHSFSINESELEKLY"
     gene            1904..2752
                     /locus_tag="PC592_003464"
     CDS             1904..2752
                     /locus_tag="PC592_003464"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDF4057389.1"
                     /translation="MLVKEIKLLRNIIKDWRKDGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIERDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPIHFGGVCLVVSKLLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNRSLSLAKEELVKGNLN
                     PKNIKELITAKINSEHLAKIDYVEIVDSETLQPVGQIENSVLVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3115..3297
                     /locus_tag="PC592_003465"
     CDS             3115..3297
                     /locus_tag="PC592_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057390.1"
                     /translation="MFKDKIDECIHIMTAYIASLKEYYSFIETQIGDFIKKYGEDTVE
                     LCLHRIMILLCECGLA"
     gene            3602..4516
                     /locus_tag="PC592_003466"
     CDS             3602..4516
                     /locus_tag="PC592_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HDF4057391.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTSKDYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSAAEQKTEEFTGIEINKNITT
                     RELNLQSGVDPEVGQDLVNYVAQLNSDAIRLLDGLINLKERVLDGVLSCTLFTSNYPL
                     LLEHIIHEANLYRSYIVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFALKFNKLIEKANEMTDSNIKSITEETLNETVEFKDFKEEGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
BASE COUNT         1842 a          536 c          721 g         1523 t
ORIGIN      
        1 tgaaaatggt aatatattta tggatggtat cttgttataa gaactatact ttaaatgttt
       61 ttaattattt tgtcttatgt aactcatatc ctcaggaatg agattagaaa ttaagatgtt
      121 gtatcacaaa gtggaggtga tactattaaa ataggtttta ttggttctgg aaaagttgga
      181 acatctttag ctaattattt tttgtcaaaa ggttattgtg tatcaggctt ttatggaaga
      241 aatcaattat ctttactaga atcaacaaat ttaacaaaaa caaagattta cagcaatttg
      301 aaagatataa tttatgaaaa cgatatatta tttattacaa catcagatga ttctattgaa
      361 attatagaca aaaaactttc caaatttaat ttaaaacata aatatatttg tcacacaagt
      421 ggctctttaa aatctagtat attgttctgt tcaaaaaaag caggtgcatt aatttattct
      481 atccatccta tatttgcatt ttccaataaa aatactgact taaaaaaaat gaaagacatt
      541 tgtttttcca tagaaggtaa taatgaacaa ggtgatttag ttattcaaaa tttcatagat
      601 agtttgggaa accaattttt tataagagat aaggatactt catctactta tcatttagct
      661 aatgttttag tttcaaattt agtattatct ttactagata taggagtaag ttactttatc
      721 aaattaggtt tatctgaaga ggaatcttta aaagccatca ctcctttagt tgaaaaaaat
      781 atagaaaata tacttgataa tggctttact aaagctctta ctggtcctgt ttctcgtgga
      841 gatataacac caataatgaa acatctatct gtattggata aaaaagatga ggaaatttat
      901 aaaatactct ccttaaatct actaaaaata actgccttag gaaatgataa cttattaaaa
      961 tgtacaaaaa atattactat agaaaatgca gtagaaaatt taataagtaa atctgaaaaa
     1021 tacaagaaga tttacaaact tttaggagga aaaaatgatg aaaaatacta tactgacttt
     1081 taagaatgct aaatatgaag gaaaaaaact atctatgctt actgcttatg attattcaat
     1141 ggcaaaaata atggatgaat gtgatataaa tggcatttta ataggagatt cgttgggaat
     1201 ggtaataaag ggtgaagaaa acactctatc tgttactata gatgaaatta tatatcatac
     1261 aaaggctgta aaaaatggcg taaaaaatgc cttaatcgta agtgatatgc cttttttatc
     1321 ttaccatgtt tctatagaag atacagttaa aaatgctggt agacttgtaa aagaaggagg
     1381 agctcatgct gtaaagttag aaggtggctc aaacattata aagcaaatag aaagcattgt
     1441 aaatgcccag atacctgtaa tgggacattt aggattaact cctcaatcag taaattcatt
     1501 tggtggattt aagattcaag gaaatactag tgaaacagca agacaactta ttgaggatgc
     1561 taaattaata gaaaaagcag gtgcattctc tattgtcctt gaaggagtgc ctacgaaaat
     1621 agctgagatg gtaactaact ctatttcaat tcctacaata ggtataggag caggaattaa
     1681 ctgtgatgga caaattttag tttatcaaga tatgttggga atgtttggag attttgttcc
     1741 taagtttgta aagcagtatg caaatatagg agatataatg agggattcaa ttaaaaatta
     1801 catactagaa gttaagacag gtgcattccc acaagaaaaa cacagctttt caataaatga
     1861 atctgaatta gaaaaattat actaatatta aggatggtac aaaatgcttg taaaagaaat
     1921 aaaattacta agaaatataa tcaaagactg gagaaaagat ggctattcta tagggcttgt
     1981 tacaacaatg ggatttttac atgaaggaca ccaaagtctt ataaaaaaag ctgtaaaaga
     2041 aaatgataaa gtagtagtga gcgtatttgt aaatccaact caatttggac caaatgaaga
     2101 ttttaatagc tatccaagag atatagagag agattttaaa tactgtatgg atagcggtgc
     2161 aacagtagtc tttaacccat caccagaaga aatgtattta aaaggtaatt gtactaccat
     2221 caatgtttct ggacttacag attttctttg tggagctaaa agacctattc attttggagg
     2281 tgtctgccta gttgtttcaa agcttctaaa tatagtaaca cctgataaag cttattttgg
     2341 agagaaggat gcccaacaat tggcagtaat taaaaggatg gtcaaggatt taaatataga
     2401 tacagaaata ataggttgcc ctataattcg tgaaaatgat ggattagcaa aaagttcaag
     2461 aaatacatat ctctctgagg aagagcgaaa atctgctcta atcttaaata ggagcttaag
     2521 tttagcaaaa gaagagctag taaaaggtaa tctaaatcca aagaatataa aagaattaat
     2581 aacagctaaa ataaattctg agcacttagc aaaaatagac tatgttgaaa ttgtagatag
     2641 tgagacatta caacctgttg gacaaataga aaattctgta cttgtagcaa ttgctgtgtt
     2701 tataggaaaa accagactaa ttgataattt tacatttgag ttaaatatat agtctgcaat
     2761 tttatataat acatctaaaa aataataaat tgcttagaaa ataatagatt acaataacta
     2821 aaattttaaa actaaattcc ttaaaaatat gattaattgt aattatatat gtatactatt
     2881 attacactta tattaatcta tattaaacct ctactaattt aagtaaacct ttaactggat
     2941 aatttttcct ttaaaaatga aaatttatcc agttttgcga ttataataac cagttttaca
     3001 tatccacttg taaaatatat ctaagcaata tatcatacta tatagatttg tgagtgaaat
     3061 aatatctgct atttactgaa tatttttatt tttcgttttt tagggggatt agttgtgttt
     3121 aaagataaga ttgatgaatg tattcatata atgactgcat atattgctag tttaaaagaa
     3181 tactattcat ttatagaaac tcaaattggt gattttatta aaaaatatgg agaagatact
     3241 gtagagttat gtctccatag aataatgatt ctactatgtg aatgtggttt agcataaaat
     3301 taaatacatt aaagtgggta agaagagtcc tatgtaaaac tcctcttacc cactttaata
     3361 tgtagactta gtttaatcta aataactaag ttataaaatc atattataat ttataataag
     3421 aagcaggtta ataaatcaaa tttgttttat aatccaacat aaatattaag aaaaaggatg
     3481 taataagatt cttgttgata ttagtgtcaa ttgaatttag ttaatttatt tataatatac
     3541 ataaatttaa atattacgaa tagagtatta taaataggat actttctaaa gggaggaaat
     3601 tatgatagat aatcaaaaat atgttatttt atcactagaa ttacacttat ttttttcaag
     3661 aattatgaaa gagcatgctc tttttttaga agcaggattt acaagtaaag attataatct
     3721 tgctatggaa gctgaccact ataaaaagca atttgaagat ttattatcat acacggttag
     3781 tgctagtaat ggtataatta gacctgatat attatattca gaagaacttg taactactct
     3841 tacatcagct gcagaacaaa aaacagagga gtttacagga atagagataa acaaaaacat
     3901 aactacaaga gaattaaatc tacaaagtgg tgtagaccca gaagttggtc aagacttagt
     3961 taactatgta gctcagctta actctgatgc aataagatta cttgacggac ttattaattt
     4021 aaaggaaaga gtcttagatg gagtactatc atgtactcta tttacctcaa actatcctct
     4081 acttcttgaa catataatac atgaagcaaa tttatatcgt tcttatatag ttgacctcga
     4141 aaataaaata gacattgagt caaaaaacgc taaagaaata gaattattct gggaccatat
     4201 tatgatggaa cacgctctat ttatgagagg attattagac ccttctgaag gtgaactaat
     4261 aaatacttca aatgattttg ctttaaaatt taataaatta attgaaaaag caaatgaaat
     4321 gactgattct aatattaaga gtattacaga agaaactcta aatgaaactg ttgaatttaa
     4381 agattttaaa gaagaaggag catcaggaat agaacagtgt aagataaaat ctataatatt
     4441 accactttta gcagaccatg ttttaagaga ggctaatcat tatattagaa tattggagag
     4501 ttataaaaac atgtaattaa aaaatacttt taaaacaata tttagataaa ataaaggtac
     4561 ttcaactgta cctttatttt tttatacgct tatagaattt aaacaagtta tttataaaac
     4621 aa
//
LOCUS       DAMKOJ010000155         4617 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000155 DAMKOJ010000000
VERSION     DAMKOJ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4617
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.164"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            173..571
                     /locus_tag="PC592_003467"
     CDS             173..571
                     /locus_tag="PC592_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF4057392.1"
                     /translation="MTKKIKHVLITTNNIENYINFYKKFGFSFKETSEKYKFNAGNVK
                     INLNIKGHEFLPQGENVQTISTNLCFKIDTNIDEPKKYLEQNEIQIKRVIVECTEVFS
                     NMKSICFKKTDVNLIELSNHRILESKPWKI"
     gene            559..1497
                     /locus_tag="PC592_003468"
     CDS             559..1497
                     /locus_tag="PC592_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF4057393.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDVHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKNNKTRGALIQ
                     GIFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVIILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIIFGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMSQQ
                     MDSDSELAGQIVVFTSAFSIITVFLIIFILKQNNLI"
     gene            complement(1857..2081)
                     /gene="secG"
                     /locus_tag="PC592_003469"
     CDS             complement(1857..2081)
                     /gene="secG"
                     /locus_tag="PC592_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDF4057394.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2224..2445)
                     /locus_tag="PC592_003470"
     CDS             complement(2224..2445)
                     /locus_tag="PC592_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4057395.1"
                     /translation="MVFYEFRYFRPAFWGTPVAKKGLQFCIDGLRNLGYPYITIWVLK
                     DNIRVIKFYKKMVLLVMILRKIYVLEKNY"
     gene            2511..2941
                     /locus_tag="PC592_003471"
                     /pseudo
     CDS             2511..2941
                     /locus_tag="PC592_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429569.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(3042..4334)
                     /gene="eno"
                     /locus_tag="PC592_003472"
     CDS             complement(3042..4334)
                     /gene="eno"
                     /locus_tag="PC592_003472"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDF4057396.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1613 a          729 c          538 g         1737 t
ORIGIN      
        1 taaactcagt aactctacat aaagttttat aatctaaatg aaatgcaata acttatataa
       61 aatttatcaa tcgacataaa aattaataat ttttatagac attatcaatc tatataaaat
      121 ttaataaccc atataaattt aaataatttt tataaaatct taaggagttg ttatgacaaa
      181 aaaaattaaa catgtactca ttactactaa taatatagaa aattacataa atttttataa
      241 aaaatttggt ttttcattta aggaaacaag tgaaaaatat aaatttaatg ctggaaatgt
      301 taagataaat ctaaacataa aaggtcatga atttttacca caaggtgaaa atgtacaaac
      361 aatcagtact aatttatgct ttaaaataga tacaaatatt gatgagccaa aaaaatactt
      421 agaacaaaat gagattcaaa ttaagcgagt aattgtagag tgtacagagg tctttagtaa
      481 tatgaaatct atttgtttta aaaaaactga cgtaaattta attgaattat cgaatcatag
      541 aatcctggag agtaaacctt ggaaaattta atcctatcaa taaatgttgt tcttcctttg
      601 tttctcacaa tgtcacttgg atatgttcta aaaaaattag gtctatttga tgtccatact
      661 ttaaataaaa tgaataatgt ctgtttcaag tctttcttgc cattattatt attttttaat
      721 atatacaata cagatttaga tggttctctt aattttaaac ttatggctgt agctgttata
      781 attatttttt caatcttctt aatcttagtc tttattattc ctaaaattga aaaaaataat
      841 aagacaaggg gtgcattaat acaaggcata tttcgtagta atttcgttat atttggtatt
      901 cctgtgacaa tttcactatt tggtgataag agtattggtg tcacatcttt attgattgca
      961 gttattgtac ctatgtttaa tgtattatct gttataatac ttgaaatttt tagaggaggc
     1021 aaagtaaata taaaacatat gattaaaagt gttttaacaa atccactcat aatcgcctct
     1081 tttataggat tgacaatgct cattttaaat attaatatac ctacattttt acacaaaact
     1141 attggtgata tttctaagat agctactcct ttatcgctta taattctagg aggttctttt
     1201 agtttttctg ctataaaagg acatataaaa cctattatat ttggggtatg tggaaaactt
     1261 atacttgtac ctgctatatt tttgccaatt agtatttttc ttggatttag aaatgtagaa
     1321 ttagcttcac ttatgataat gttatctgct ccaactgcag tttcttcatt tacaatgtca
     1381 caacagatgg attctgatag tgaattagct ggacaaattg tagtatttac ttctgcattt
     1441 tctataatta cagtattttt aataatattt attttaaaac agaataatct tatttaatga
     1501 tatgcaatag gataaattag tattatgaga aacatatata aaattgattt agttacataa
     1561 aaacatatga ttatactatt tttactatat aactttatgt atattatctt gtgaaacatg
     1621 ttgaaagtac tgttgttatt tattgcttga tttaaaaaat atataaatac aaacaataga
     1681 tattaataga tagtcaatct ataaaataaa aactggacta atcatataaa atcattagtc
     1741 cagcttttat tttacgtatt ttttatgttg acttactttt attaaaaact aaatttaatt
     1801 tttaaatgtc tagcaaatgc actaattaaa taatggccag ttattcaaca atatcactac
     1861 ttcttaacta taagtaatgc caatgcattt ataaaaaata atactgctgt tatctttgta
     1921 actctagcaa gaaatgcttg tttccctttt ggtttaaagt aagcttgact tccctctcca
     1981 ccaaactctg aaggtaaagc attttttgaa tcttgaggca ttatgctaat tactagtaaa
     2041 atccctagca ctacttgcac acccattaaa atgttgctca ttcttgcccc tcctatctgt
     2101 ttattactta aatttcatta ctctttagtg tatcacaata atatagccat ttcaagacta
     2161 ttatgctata aatcacatac aaaaaaatat ataattactg tgtctttttt aggtaacata
     2221 tttctaataa tttttttcca atacatatat ctttctcaaa atcatcacaa gtaaaaccat
     2281 ttttttatag aattttataa ctctaatatt atcttttaga acccatattg ttatatatgg
     2341 atatcctaaa tttcttaatc catcaataca aaattgtaat cctttttttg caacaggcgt
     2401 tccccaaaac gctggacgga aatatctaaa ttcataaaaa accatcctat ttacaaatta
     2461 atacgactat catattatat tagtacgata atcgtattat atggaggtaa atgtcaatga
     2521 atgctataaa agaactaagc aacctatggc acaacgttgg tatacaaatg aaaacagaaa
     2581 tgtgtagtgg taaatatcct actatttctg gtatttcttt agtagaatta agtattttag
     2641 aaatagtcga gcaacatcca aatagtatga taaaagaaat tagttcaact ttagaatttc
     2701 caaaaagcac attaacaagt gatgtaaaac gtcttgagct aaaaaactta taaatagaaa
     2761 tccttgcttt aaggataaaa gggcgtataa tttagattta actgaattag gtttaaaagc
     2821 tcaaaaagaa catagagaaa tagaagcaac tgtatttaaa aatatcctac atcaattaga
     2881 taaaggtgag atagaaacat ttattcatat tttttctcaa gctgtgaata aaattaggta
     2941 ataatatata aaaaaggata agtgaattga aaaatcaact aacacttatc cttatataag
     3001 acaaacttaa acgttttata ctatttcttt aatcttaata actatttttt taagttatag
     3061 aaagatttta atccacagta tctagcttgc tctccaacca tttcttctat tcttaataat
     3121 tggttgtact tagcaactct atcagttctt gatggagcac cagtttttat ttgaccagca
     3181 tttactgcaa cagctaaatc tgctatagta gaatcttcag tttctcctga tctatgagat
     3241 ataacagcag tatatcctgc tctcttagcc atttctatag catctaaagt ttcagttatt
     3301 gtacctattt ggttaacttt aactaatata gagttagcta ctccattttc aattcctttt
     3361 tctagtctct ctgtgttagt aacaaataag tcgtcaccaa ctaattgtaa tttatttcct
     3421 aatttttcag ttaataactt ccatccatcc caatcttctt catctaaacc atcttctata
     3481 gttattattg ggaagttgtt tgaccaatct tcatataaag caaccatttc agcagcagtt
     3541 aactcttttc cttctcctgc taaaacgtat tttttagttt ctttgttgta catttctgta
     3601 gcagcaacgt caagacctaa cataacatct tcacctggct tatacccagc ttttgttata
     3661 gcttcaacta ttaattctaa agcttctctg tttgaaccta agtttggagc gaatccacct
     3721 tcgtcgccta caccacaagc taatcctttt tctcctaaaa ctttctttaa tgaatggaat
     3781 acttctgctc ccattcttaa accttctttg aaacaacaag ctcctactgg taatatcata
     3841 aattcttgaa catcaacgtt gttatcagca tgctctccac cgtttaatat gttcatcatt
     3901 ggaacaggta attgtttagc atttactcca cctaaatatt ggaataatgg taaacctatt
     3961 tcatcagcag ctgctctagc tactgccatt gaaacaccta atatagcatt agctcctaat
     4021 ttacctttgt ttggagttcc atctaattct atcatgattg catctatagc tggttggtca
     4081 aatgcatcca ttccttctat ttcaggtgct attatttcat ttacgttagc aacagctgtt
     4141 tctacacctt ttcctaagta tcttccctta tctccatctc ttaattcaac agcttcaaaa
     4201 gctcctgtag aagctcctga tggaactatt gctcttccca ttgctccatc ttctaatact
     4261 acttcaactt ctacagttgg atttcctctt gagtctaata cttctctagc atatactaat
     4321 tcaataactg acatttgtat atctcccttc gattttctat tagttaaaat ttcatttact
     4381 gtaaacatcc gtctactatt ttaatctact ttctatatta tagtacataa agttgctttt
     4441 gaaaattagg tacaaattta tttgatgggt aaatttgtaa aagttcctat ttttatttta
     4501 ttttttataa tattttaatt tatataatat aaaaaaactt gtctaaaatc caaaaccaat
     4561 cttaaataca cgaatattat aactagattt aaaacattaa acataaaatg tacaact
//
LOCUS       DAMKOJ010000156         4443 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000156 DAMKOJ010000000
VERSION     DAMKOJ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4443
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.165"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..2558)
                     /gene="carB"
                     /locus_tag="PC592_003473"
     CDS             complement(<1..2558)
                     /gene="carB"
                     /locus_tag="PC592_003473"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003467946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HDF4057397.1"
                     /translation="MPKLDNIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIAENEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHQLKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFSDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGV"
     gene            complement(2751..3800)
                     /gene="carA"
                     /locus_tag="PC592_003474"
     CDS             complement(2751..3800)
                     /gene="carA"
                     /locus_tag="PC592_003474"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF4057398.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESIGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITVFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(4057..>4443)
                     /locus_tag="PC592_003475"
     CDS             complement(4057..>4443)
                     /locus_tag="PC592_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF4057399.1"
                     /translation="VVLATVNNHDKDEFIEIAKDMKELGYTFVATEGTAKSLRENGIE
                     ADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRTAIEFSTEIMTSL
                     DTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT         1271 a          885 c          451 g         1836 t
ORIGIN      
        1 actccactta ctttgcttat atatggaact gttctactag ctctaggatt aacttcaatt
       61 atatataatt cattttgaaa ttctataaac tgtatattaa ccataccaag cacattaagg
      121 tctaaagcta tttttttagt atattctact atcttttctt ttatttcatc agatatattt
      181 tgacttggat acattgttgt actatctcca gagtgaactc cagctctttc taaatgttcc
      241 attataccag gtattaatat atcttcctta tcacatatag cgtctacttc tatttctcta
      301 ccagttagat atttatctat aagtactgga ttcttatggt ctctatcaaa tgcatcatcc
      361 aaatactgaa ttagtttttc ttcattataa gttatttcca taccttggcc accaagtaca
      421 taagatggtc taactagtac tggataacct aattcctttg caatttcaac accttcatta
      481 gttgtccata caccttttcc ttttggtcta tttatatcta gtctttctag taaatcatca
      541 aacttctctc tatcttctgc tgcatctata tcgctaaaat ctgttcccag tataggtata
      601 tttttttcat gtaagaactt agccagtttt atagctgtct gtccaccaaa ctgtaatatt
      661 acaccttctg gtttttcttt ttctattata tttaaaacct cttcttctgt taatggttca
      721 aaatataact tatctgatgt atcaaaatct gtacttactg tttcagggtt attgtttaca
      781 attatggttt ctatgtccat ttttcttaaa gattttacac aatgaactga acaataatca
      841 aattctatac cttgacctat tcttattgga ccagaaccca atactaccac ttttctctta
      901 tcactaacaa ctacctcatc atattgctca taagttgaat aatagtaagg tgataaagct
      961 tcaaattctc ctccacacgt atcaaccatt ttatatactg gttgtatatt atataaactt
     1021 ctcaattcat ataatttttc tggacttatc ttcattaagt cagatatacc tttatccgaa
     1081 aatccttttt tctttaattg atgtaaatat tctttatcta agtcttctat ttttaaaact
     1141 tttaattttt cttcttgctc tactatccat ttgaatttat ttataaacca cttatcaaca
     1201 ccagttattt ctgatatcat ttctacttta tagcctcttc ttatcatttc agctaagtca
     1261 aatagtctct catcatcagg cactactact ctagccttta attcctctaa tgttctacct
     1321 tctgatggtg catgaaccaa cgaatatttt cctgtttcaa gtgatcttat ccctttaaga
     1381 atagcagctt caaagttact acctatactc ataatttcac cagtcgccat catcttagtt
     1441 cctaattttc tattggcatg tctaaattta tcaaatggcc actttggtat ttttaccact
     1501 acataatcta atgttggctc aaaacaagca taagttttct tagttactgc attttctatc
     1561 tcatctaaag tgtagcctaa agctatctta gctgctactt ttgctattgg atatcctgta
     1621 gcttttgatg ctaaggctga tgacctactt actcttgggt ttatttctat tatcgcatat
     1681 tctaaactat gtggatttaa agctatttga acgttacatc caccttgaac ctctattgca
     1741 tttattatgt ctattgatgc ctttctaagt agttgatact cttcatcact tagggtttga
     1801 cttggagcaa caactatact atctcctgta tgaactccga ctgggtctac attttccata
     1861 ttacatacag ttatacagtt tccatttcca tctctcatta cttcatattc tatttctttc
     1921 caacctttta tactcttttc aagaagaact tgtccaacag ggcttaattg tagtccatgt
     1981 gaaagtattt ctcttaattc ttcctcattt tcagctatac ctccaccagt tccacctagt
     2041 gtgtatgctg gtcttacaac tactggatat cctattttat tggcaaactc aagacctgct
     2101 tctaaatttg taactatgtc actaactatt acaggttgat ttatttcttt cattacttct
     2161 ctaaataaat ctctatcttc tccctttttt atagactcta tagatgtccc tataactttt
     2221 acattatatt tatctaatat cccagcatca tgtaattcta cagctaaatt taatcctgtc
     2281 tgaccaccca tacctgcaag taaactatct ggtctttctt tttctattat tttttctata
     2341 aattctattg ttaatggttc tatatatatt ttatctgcaa tctctttgtc agtcattata
     2401 gtagctgggt tactatttac taatacaact tcaattccct cttcttttaa tgcttggcag
     2461 gcctgtgttc ctgaatagtc aaactctgca gcttgaccta ttattattgg tcctgaccct
     2521 aatactaaag ttttctttat attatctaat ttaggcataa ctctttctcc ttatctaaac
     2581 aatttttaca gctcttatct tcatcatcta tacaatcaat tttaattact ttatttcata
     2641 ttaagttcaa atttacgtat taatacatcc atttaataca tctatgttaa ttaaaccaaa
     2701 ctttttgatt taagttattc ttatctttta gttatctatt ctaatattat ttattttact
     2761 aactctaaaa atttatcaaa aatatagtca ttatcttttg gtcctgggca agcttcagga
     2821 tggtattgaa cactgtatac atctaacttc tcatgtctca ttccttcaac agtattatca
     2881 tttaaattta tatgtgtcac tttcatttgt tcaggaactt ctgaaacata ataaccatga
     2941 ttttgagaag ttataaatac ttttccctct tctaaatctt taactggatg atttccacct
     3001 ctatgtccaa atttaagttt agcagttttt cctccaagag ctaaagctaa aagttggtgt
     3061 cctaagcata ttccaactat aggtttttta ccaataagag cctttatatt ttctataaca
     3121 tcttctaggt cttctgggtc tccaggtcca tttgacaaga atattaaatc agggtttata
     3181 ctcaatacat cttctggaga tgttgtagct ggaaatactg ttatatcaca tccacgagct
     3241 ataaacgatc ttaatatatt tctttttacc ccaaaatcca taacagccac ttttggacca
     3301 tttcctttta tatgctctac ttcttttctt gtaacagttc taactgcttc tgtatttgaa
     3361 aacttatcca atttatgttt aacatcttct aatttactgt cttctaatgt aattatacct
     3421 ttcattgtcc cattatttct aagtatctta gtcaaagctc ttgtgtctat tccttcaagt
     3481 ccaataacct tattttgctt taaatattgg tctatatcaa tttcacatct aaaattactt
     3541 ggagaatcac ttttctccct tactatgaat ccctttactt gaactttttc agactctgct
     3601 gatgataaat ttataccata atttcctaca agaggataag tcatagtaac tatttgacca
     3661 tagtaagaag ggtctgttaa aacttcacca tatcctatca ttgaagtatt aaatactact
     3721 tctcctatac tttcttctaa atatccaaat gcctttccta taaaaactgt tccatcttct
     3781 aatattaacc ttgctttcat actacagtac ctcctataat tctctttaga taaactaaag
     3841 aacattaact aaatataagc ttttaaatat ctatatctat ttttcacttt tacattctag
     3901 ttttatactt atttgcattt attttttatc tttttctatt atactacaaa tttcttaaaa
     3961 aaaagaagtt atctcaaaag taaaaacccc tagaaaaaat aacctctttt tttaatttaa
     4021 taattaaatt cttaaactat acaatcaact taatttctat tcagctatat tgtaaacttt
     4081 taacttatct ttatttaaat gtttcttctt aacttctact aaagctttta gtgtatccag
     4141 agatgtcatt atttcagtag aaaactcaat agctgttctt cttatcttaa acccatctct
     4201 tgtggagtca tttcctttag ttggtgtatt tattactata tcaacttgtt tatttcttat
     4261 agcatctaat atgtttggtc tagactcttc tactctattt actatatcag cctctattcc
     4321 attttctctt aagctcttag ctgttccttc tgtagcaaca aaagtatatc ctaattcttt
     4381 catatctttt gctatttcta taaactcatc tttgtcatga ttgtttacag tagcaagtac
     4441 tac
//
LOCUS       DAMKOJ010000157         4437 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000157 DAMKOJ010000000
VERSION     DAMKOJ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4437
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.166"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            418..2313
                     /locus_tag="PC592_003476"
     CDS             418..2313
                     /locus_tag="PC592_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HDF4057400.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAQDSDNKLTATIKSTS
                     TVEVKRAKDSTNVITLNVGDQHLDFSKVITSEDGTFEGYEKSYSDIESKELHTITVKN
                     ADLQDITAEELFDGIRLTTLGRELVNKVKNGYTLTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKLETISVSSKNHKLVRELHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIESEILRV
                     LGSNLSSKKIYIVGGESKISKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            2776..4179
                     /locus_tag="PC592_003477"
     CDS             2776..4179
                     /locus_tag="PC592_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HDF4057401.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILVNSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKANTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGV
                     TGEADAISASPVAARDGVPIILTDGNSMGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFDTNKRVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     DNGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
BASE COUNT         1912 a          447 c          787 g         1291 t
ORIGIN      
        1 ttttatcaat tacatgtatt agaataattt ttaattttaa attctaattt atgatgattt
       61 ttgtaatatg ttatgcattt taatatatgg agatagatat taattcagtg atatatattt
      121 aagtaataag agaaagcaaa aattagtgca tagtagtata taaaagtgga gtttgaataa
      181 ttttgttagt atatgattgt ctaatataaa atcactataa aataagggtt tctatctttg
      241 gatataatca taaacagcta agtgggggaa ggggttcaag aagatattac tattgtttgt
      301 gttagtaaat tatgtaaaca tataaaatat attgaaaaat aatattatat ataatattat
      361 ttatatgtga gaaatacgaa tataaaaaat caaaaacaat attcggagga cataaatatg
      421 ttgagcaaca aaaaaagaag tatggcaata gtaatggcag gagctacagt tatgagtgca
      481 gctgcaccaa tattcgcaga taatactgtg acagaaaatg ttgataaaaa ttacacagta
      541 agtgcgaaag attctgctaa actaatcgaa gaggttagaa aagcattaga agttaagttt
      601 gaagatacaa aagcaggagc aaatgtaaat gatagagttt acgatataaa agtagacaat
      661 gtaaacttaa ctaatgcaac tcaattacaa aataaaataa actcattaac agaagggcaa
      721 agtttaaaag ttactattca agataaagga catcaagttt taggtggaaa agtagttgac
      781 tataaaattg aaaactacaa aactgctcaa gaaatagtag atgcagttaa tgcttacaat
      841 gcaactttag cacaagattc tgataacaag ttgacagcaa ctataaaatc tacaagtaca
      901 gttgaagtaa aaagagcaaa agattcaaca aatgttatta cattaaatgt aggagaccaa
      961 catttagatt tctcaaaagt aataacatca gaagatggta cttttgaagg ttatgaaaag
     1021 agttatagtg atatagaatc aaaagaatta catacaataa cagttaaaaa tgcagattta
     1081 caagacataa cagcagaaga attatttgat ggaattagat taactacatt aggaagagaa
     1141 ctagttaata aagttaaaaa tggatatact ttaacatttg aaaatgaagc aatccttact
     1201 caagaacaag aagatagtga tgataaagat aagccagaaa aatcaagctt tgatatagtt
     1261 ttaagtaaag caaatgaaaa gctagaaaca ataagcgttt caagtaaaaa ccataagtta
     1321 gttagagagt tacataaagt attgacagat gtaaaagacg gaaaagaatt aaaagtagaa
     1381 gttttatctg gtgattcaag atttacaaca gcagtagaag ttagtaaaga gagattcaaa
     1441 gatggagaag cagaagcaat aattttagtt ggagaagatg ctatagttga tggattagca
     1501 tcagcaccac ttgcatctca aaaaaatgca ccaatattat tatctaaaaa agattcatta
     1561 ccatcagaaa tagaatctga aatattaaga gtacttggaa gtaatctatc ttctaagaaa
     1621 atatatatag taggtggaga atctaaaata tcaaaagaaa ctgaagaaaa actttctaaa
     1681 ttaggtgtaa gcaaagttga gagagtttct ggagaagata gatttgaaac ttctttagaa
     1741 atagcaaaac aattaaaaga tacatttaag actgcttttg tagtaggtgg aaatggagaa
     1801 gcagatgcca tgagtatatc agctagagct gctcaatttg gtgctccaat aatagttaca
     1861 ggtaacgaat tagatgcaaa tgctgaaaaa ctattaaaag gaaaagaatt agaaatagta
     1921 ggtggagaaa attctgtatc aaaagaagtt gaagataaat tggttgatat agatttaaat
     1981 aataaagttg aaagacttgc tggagaaaat agaaaagata ctaatgctaa agtaattaat
     2041 aagtactacg caggtgcaac taaagcatat gttgcaaaag atggttatgt aggtggaaac
     2101 ggacaattag ttgatgcact tacagcagca ccacttgcag ctagttcaaa agctccaata
     2161 gtattaacta cagaagaact ttctaaatca caagaagaag tagttgagct aagacttaag
     2221 aatgctacca agttagtaca aataggtgaa ggaatagcta aaaacgcgat tgaaaaaata
     2281 gcagaaaaaa taaacttatt tactaagaac taataaaata taagaatgaa tattaaaagt
     2341 ttacttagat aatatgtggt tatacaatat gtcaatgtat aagacatagt gtagatatta
     2401 gaaaatatat aaataatgaa atcaaaataa taagaataag gtatctcatt tataaattag
     2461 attgagatgc cttattttat tttttgatta tagcattggg aaattcatac tataaaaaat
     2521 tattataaat gatactgttt acaaggatta aatgtcttat taacatatat tattttgaat
     2581 ttattactta attaaataaa taagttataa tgttttgaat ttatgaagaa taaaaacttt
     2641 aagtatattg tttgagttgt atggataact atggtatcat atataaaata tggtaacaaa
     2701 actgtaactt ttgattcaaa atgaacaaaa atactaataa aaaatgtgaa aagtatattg
     2761 ggggtagaga ataatatgaa gaatagtaaa aagatattgg ctataggact tacactattt
     2821 ttagtaatgg taaatactcc tatggtaaat gcgttgacat cagttgagca aataaaaggg
     2881 aatgacagat atgagacagc agcaaaaata gcagataagc aaaactataa tacagcaata
     2941 ctagtcaatt cagataacag cttggcagat ggattaagtg caagtggttt ggctggagct
     3001 ttaaatgcac ctattttaat gacaaaacaa aatcagattc caaatacaac tatggaaaga
     3061 ttaaacaaag caaatactgt atatataata ggctcagaat caacaataag taagaatgtt
     3121 gagaatcagt tactatccaa aaagaaggtt gtacaaagaa tatttggtga aaatagattt
     3181 gatacaagca taaaaatagc tgaaaaaatc aaagaaatta agccaataga taaagtaatt
     3241 atagcaaatg gagttacagg agaagcagat gcgataagtg catcaccagt agcagctaga
     3301 gatggagtac ctataatact tacagatggg aatagtatgg gatttgacac aacaggttta
     3361 aagagttatg cacttggttc tagtgaaata atcagtgacg aattggttaa gagtacaaac
     3421 tctattagat taggtggaac agatagattt gatactaata agagggttat acaagaattt
     3481 tataaaaata gtaaagaatt ttatttaagt aaagggttgc aattaacaga cgctttggct
     3541 gcttctacaa tagcaaaaaa tgctcctgtg gttttagttg aaaatggcag taacaagagt
     3601 attttaagtg gtgcagacaa attgactgta ctaggaggca taaatcagaa tgttatcaag
     3661 caatgtataa atcaagcttc accaaatcaa caaggcttat attacaatcc aaatgataga
     3721 gcatttaaag agcgaataaa gggtaaagta tatgctctta caaagcagta cagaaaagat
     3781 aatggagtaa gagccttatc tgtagcaagt agattagaag gattagcaaa tgattggtct
     3841 aatttaatgg caaataagaa gaccttatct catacgataa atggaaaaaa ttcatattct
     3901 acttttttga aatacctaga ttggagtgag attaaacctg gatatattgc agttcaaggt
     3961 gaaaatataa ttaaatataa aattccagat aaacctgtgt atacaaatag agatgcagat
     4021 gatataggaa actttatttt taatgagtgg aagacaaatc cagaagaagg tactaatatg
     4081 ttgcataaag ggtatgaaat aatgggattt ggtatagcta taacaggaga taagaatcta
     4141 tatgctacac atgaatttta tggaagatat aaagaataaa taaaaacaat ttgtaagtta
     4201 taattactac taatatgtca gataaatcac aaaaatatca ttaaaaaata aaaattcatt
     4261 tagattgttt aaaataggta gagaaatagc ttcatatata gtagataaaa ttaggagctt
     4321 aattgaaaaa taagtatata ttgaatgaac tgaaaataag aatgtattta gatataaata
     4381 atatgtctaa aaatacattc ttatttttat tttcattgtt ttaataatat tgaattt
//
LOCUS       DAMKOJ010000158         4433 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000158 DAMKOJ010000000
VERSION     DAMKOJ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.167"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            195..1670
                     /locus_tag="PC592_003478"
     CDS             195..1670
                     /locus_tag="PC592_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF4057402.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITFEKV
                     RKEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1757..2170
                     /gene="speD"
                     /locus_tag="PC592_003479"
     CDS             1757..2170
                     /gene="speD"
                     /locus_tag="PC592_003479"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDF4057403.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2200..3051
                     /gene="speE"
                     /locus_tag="PC592_003480"
     CDS             2200..3051
                     /gene="speE"
                     /locus_tag="PC592_003480"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDF4057404.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKKYMDICSCKLDDERVNLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3041..3919
                     /gene="speB"
                     /locus_tag="PC592_003481"
     CDS             3041..3919
                     /gene="speB"
                     /locus_tag="PC592_003481"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDF4057405.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVYEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFEKIVNMLNGKNIYITIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISEKIK"
     gene            complement(4099..4299)
                     /locus_tag="PC592_003482"
     CDS             complement(4099..4299)
                     /locus_tag="PC592_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF4057406.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1759 a          496 c          749 g         1429 t
ORIGIN      
        1 ataaaaaagt ttataaatat tgatataact gatatatgtg tttttgatta acttcaaaaa
       61 aacacttgta aaaatgctgg aatgttaata taataaatat catgagttta ataaaagtaa
      121 aaataaaaaa tagaaataat aaataataaa tattaaaaat gtttgaatat agagaggaga
      181 tgaatttaaa aatcatggat agcgagtttg caaatgcagt tgaattaagc tatgagtgtg
      241 ctccattatt agagtcgtta aaggaatact cagagaaaga catagcttgt tttgatgtac
      301 ctggacatgt aaaaaataga ggtgtagcta tattaaataa atatctaggt gaaagtctca
      361 tgaaaatgga tataaattca tcaccaacta tggataatgt atctgcccca aatgggatta
      421 taaaaaatgc acaggatttg ctagcacaag catatatggc tgatgaggca ttctttataa
      481 cgaatggcac aactcaagca atacatgcaa tgattttgag tgttataaaa ccaggtgaaa
      541 aagtattact tccaagaaat atacataaat cagtgataaa tgcattaata ctttgtggag
      601 gaatcccaat atttatacaa ccagaatttg atgaaaaatt aggtataagt ttaaatatta
      661 cttttgaaaa agttagaaaa gagatagaaa aagattgtaa tataaaagca ttatttttcc
      721 ttaatccaac ttactatgga gtttgtgcag accttgagag tattatagaa ctatgccata
      781 aaaataatgt tttagtgtta gttgatgaag ctcatggtgc acattttcca tttcatttag
      841 atttacctcc ttctgcaata agtttgggag ctgacatggt agctgtaagt atacataaaa
      901 ctggaggagc attgacacaa tcttcagcac tcttattgaa tagagataat gtaagctttg
      961 aaaaggttct tcaatcaatc aatatgctac aatcaacatc agcatcttat ttgcttatgg
     1021 caagtataga tggtgctaga gttaatctag ttgagaatgg tgaaaagcaa ctgtcaaaag
     1081 cattaaacct atctaggtat gcaaaatcta aattgaacaa aattgatgga ataaaagttt
     1141 tatctacaga aatattaaaa caaaaaggtg ttaaatttat agatgaaaca aaattgtgta
     1201 taaatgtaaa agaattaaat ttgactggat ttgaagtata cgatttatta tataaaaatt
     1261 tttcaattca agtagaatta ggagattcat ataatattct ggcacttgtg tctattggaa
     1321 caaataaatc agatatagat agattagtaa aagcactttc tataattgca aagatttata
     1381 gaaaagaatc aacattaaat gaatttaata tggttcaaat aaatccaatt attaaactta
     1441 atccaagaga agctttttat gcaccaaagg aaagtgtaga aattaattca tgtatagata
     1501 gaatttgtgg agaatcaata atggcatatc caccaggtat accgattatt gctccaggag
     1561 aattgataac agaagaaatt atggagtata ttattttctt aaaaaatagc aatgcatatc
     1621 ttacagatgt acaagataaa aacttagata gaatactagt aataaaataa attattttat
     1681 tttgcaaggg caagtgtttg ttaaatagat tttatcagat agaacttatt aaaagtataa
     1741 aggagttggg gttgaaatga aatttgaaac actaggaaga catatactag tagaatacta
     1801 taattgtgat gaaaacgtac ttaaagaccc acgtcttata gaaaatttta tgaatgattc
     1861 agcactaaat gcaaaggcga caattgttga ttctgtattc caccatttta atccttgggg
     1921 ggtttcagga gctgttataa ttgctgaatc tcatttgaca atacatacat ggcctgaata
     1981 tggttatgca gcagcagatt tttttacttg tggtgatata gacccatgga aaagttttga
     2041 attattagag caacttttaa aatctgaaag aagcgagtct acagaaattc caagaggttt
     2101 aactacaaaa atcaaaaaat attcaaaaaa agatttaggt aagattactc ataaaccaga
     2161 agcagtataa aacatacaag agaaagtgag gattattata tggaactttg gtatacagaa
     2221 gaatggacag aaaatgtaag attttctata aaagtaaata aacatctatt tgaaggaaaa
     2281 tctcaatttc agaggataga cgtatttgat agtgatgaat ttggaaaatt tctgacaata
     2341 gatgggttaa tgatggtaac atataaagat gaatttatat atcatgagat gataactcat
     2401 gttcctatgg ctacaaattt aaacataaag aaagtattag tcataggtgg aggtgatgga
     2461 ggtacagtaa gagaattaag ccgttatcct caaatagaaa agattgatat ggttgaaata
     2521 gataaaatgg ttgtagatgt atctaagaag tatatggata tatgctcatg taaattagat
     2581 gatgaaagag tgaatttata ttttgaagat ggcgttaatt ttgttaaatg tgcacatgat
     2641 aaatcatatg acttaataat agtagattca actgacccaa taggaccagg cgaaggactt
     2701 ttctcaactg atttttataa ggattgttat agaatactga ctgatgatgg aattttagta
     2761 aatcaaagtg aaagtccgta ttttgacttt aatgctaaag agatgaaaag agctaataaa
     2821 aagttaaaac aaatatttcc aatatcagaa gtctatcaag cacatatacc aacataccca
     2881 tctggtcact ggttgtttgg atttgcttca aaaaaactta atccagtaaa aaatcaagat
     2941 agaaatgggt gggagaaatt aagtttaaaa actaaatatt ataatagtga tatacattta
     3001 ggttcgttta tgttacctca atatgtaaag gagatgctag atgaagaata atttctatca
     3061 tatgaatacc tttatgagta tggacaaaaa ttatgaagaa tctaatctta tagtatttgg
     3121 tgttggattt gatggaacta cttctaatag acctggagct agatttgcaa gtagctctat
     3181 gagaaaagaa ttttacggtc ttgagacgta tagtcctttt ttagatttgg acttagagga
     3241 ttataatata tgtgattatg gagacttaga aattagtgtt ggaagtacag aacaagtctt
     3301 aaaggaaatc tatcaagaaa catataagat tgttagagat tcaaaagtgc catttatgat
     3361 tggaggagag catttagtca cattaccagc ctttaaagca gtatatgaaa agtacaatga
     3421 tatatatgta attcattttg atgcccatac ggatttgaga gaagaatata ataatagcaa
     3481 aaattctcat gcaacagtaa ttaaaagaat atgggatatt gtaggtgata ataaaatatt
     3541 tcaatttggt ataaggtctg ggacaaaaga agaatttaaa tttgctacag aagaaaaaca
     3601 cacatacatg gaaataggcg gaattgatac atttgaaaag atagttaata tgctaaatgg
     3661 aaagaatatt tatattacta tagatttaga tgtattggat gcatctgtat ttccaggaac
     3721 aggtacacca gaacctggtg gtgtaaacta tagagagttt caagagattt ttaagattat
     3781 aaaaaattct aatataaata tagttggttg tgatattgta gagttaagtc ctgattatga
     3841 tactacaggt gtatcgacag ttatagcctg taaaatctta agagagttat gcttgataat
     3901 atctgagaaa attaaataga gtattttata tgaataatat gtattataat ataagaagtt
     3961 attttaaaaa aattagttta agtttaacgt ttttctaaag taacttctta tttttgtaat
     4021 taaaaataaa tataataaac aacaaaaaag agccctcgat agctcctttt ctaaaatata
     4081 tatatttaaa ttaaataatt atattctatt tacgttttca gcttgaggtc ctctattacc
     4141 ttgagttata tcaaagctaa ccttttcgcc ttcttctaaa gttttgtatc catcattttg
     4201 tatagctgag aaatgtacga aaacatcatc ttctccctct acagatatga acccaaatcc
     4261 tttttcattg ttaaaccatt ttactattcc gtttttcatt ataagaaaac ctccgcatta
     4321 ttaaaaaata caaactaaaa aaataagtct gttctattaa tataacataa aatttaaata
     4381 aaagcaaata aaatttttaa aaaaattaat tacttttaga atttaataaa aat
//
LOCUS       DAMKOJ010000159         4417 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.168, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000159 DAMKOJ010000000
VERSION     DAMKOJ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.168"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            67..987
                     /locus_tag="PC592_003483"
     CDS             67..987
                     /locus_tag="PC592_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HDF4057407.1"
                     /translation="MNKKFRLYQVDSFTKEKFTGNPAGVITNADGLSESQMQKIAREL
                     NNSETAFIFNKLAKNHQENYDVHIRFFTPTNEVPICGHATIAAHYVRAVENQLNNKTV
                     FQKTGAGILPVDIIKKDNDYEIIMTQGKIEVSPPLQQTYQERLLNAFGILKEDIRTDC
                     PIAISSTGHSKVMIGIKELSTLNSLSPNLYELSKISQEIKCNGYYIFTLHDKETLQVH
                     GRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPIPNTEFIFEAVQGEAIKRKGKMLV
                     KVIISDNKPVEVKIIGKAVIAFSTNIEIEL"
     gene            1212..1823
                     /locus_tag="PC592_003484"
     CDS             1212..1823
                     /locus_tag="PC592_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDF4057408.1"
                     /translation="MINDIKNKFKDYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            2128..2466
                     /locus_tag="PC592_003485"
     CDS             2128..2466
                     /locus_tag="PC592_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF4057409.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVTFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(2874..4310)
                     /gene="miaB"
                     /locus_tag="PC592_003486"
     CDS             complement(2874..4310)
                     /gene="miaB"
                     /locus_tag="PC592_003486"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDF4057410.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPNMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESMNSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERIRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPE
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHERFNRVLEAVNRISAEINDGYKNRIVEVLVEGRSKNNENKLSGRTRQNKLVNFEGG
                     NDDLIGKLVMVEITEPRTFSLNGILVND"
BASE COUNT         1599 a          618 c          516 g         1684 t
ORIGIN      
        1 ataataattt atctcaagtt ttctatgtac ataaactaat ctaatgttta gaaaggatta
       61 tataatatga ataaaaaatt tcgtctttat caagttgact catttacaaa agaaaaattt
      121 acaggtaatc cagctggtgt aattacaaat gctgatggct tatctgaatc acaaatgcaa
      181 aaaatagcaa gagaattaaa taattcagaa actgctttta ttttcaataa attggctaaa
      241 aatcatcaag aaaattatga tgtacatatc agatttttta caccaactaa tgaggttcct
      301 atatgtggtc atgctactat tgctgcccat tatgttagag cagtagaaaa ccaactcaat
      361 aacaaaacag tatttcaaaa aactggtgct ggaatattac cagttgatat tataaaaaaa
      421 gataatgatt atgaaataat tatgacacaa ggaaaaattg aagtatctcc accattacaa
      481 caaacctatc aagaaagatt acttaatgca tttggtattt taaaggaaga tattcgtaca
      541 gattgtccta ttgccatatc atctacagga cattcaaaag ttatgattgg aataaaggaa
      601 ttatcaacat taaatagttt atctccaaat ttatatgaat tatcgaaaat aagtcaagaa
      661 ataaaatgta atggatatta tatttttaca ttacatgata aagaaactct acaagttcat
      721 ggaagaatgt ttgctcctgc aattggtatt tcagaagacc ctgttacagg aaatgctaat
      781 ggacctttag gtgcgtacct tgtacattat aaagtaatac ctatacccaa cacagagttt
      841 atatttgaag cagttcaagg agaagcaata aaacgtaaag gcaagatgtt agtaaaagta
      901 attatttcag ataataagcc agttgaagta aaaataattg gaaaagctgt aattgcattc
      961 tcaacaaaca tagaaattga attataggtt ccttctaagt aaatttttga actttttaat
     1021 actaatttaa taacaaacta atttatatac aatcaaatta atttttttat tatttgttaa
     1081 tatatattta tcattatatt atataataat atagatagtt actatatctt ataattagat
     1141 aaatcataat tatatattat tgttaaaact caattatata atttttaata atattatttt
     1201 aggaggtaaa aatgataaac gatattaaaa ataaattcaa agattacaaa ccatatataa
     1261 atggatacaa gaatatgaag agagcatctg ttttaattcc aatagtagaa ataaataaca
     1321 cacactatat attatttgaa gttcgctcaa aaaatttgaa gcatcaacct agcgaaattt
     1381 cttttccagg tggtaaaata gaatcaggtg agactccata tgaagctgtt attagagaaa
     1441 cttgtgagga acttggaact tttagtgaca atatagaagt aatatcaagt cttgacctcc
     1501 ttataacacc agtaaagttt atcatacatc catacttagg atatataaaa aatattaata
     1561 atttaaatat aaacaaggat gaagttgacc atactttttt ggttcctata aaatatcttt
     1621 tagagaatcc tccaaatact tatagtaata ctgtaaaagt ttttccagat gaaaatctac
     1681 catatggttc aattccaaac caaaaagatt ataaatttga aagtggaagt tatcctattc
     1741 tgttttataa atataaagat tatgtaattt ggggaatgac agcaaaaata ctagaaaact
     1801 ttttaaattt tttatcagaa taacacttat aataaatcat taaaactttt acataagaaa
     1861 ttcataaaag tttctaaatt taaaatttaa cagttctaaa atatcaagaa ctatattttg
     1921 tagcactttt ttattttatt attgtttgaa tatttgatag ttttcaatgc aatttcaaca
     1981 taaatactat gtattagtgt atactgttgc tgaattaaag tatgataatc tatttaataa
     2041 agtatgcagt aaatgatttt aatgtgtctt tatggtaaaa ttactaataa gtaataaaat
     2101 taattaaaat atatggaggt gcttgtaatg tttgctgtag gatttgttgt tataattgca
     2161 cttgcctttt tcatattaag tgtactatta tttaatggaa aagccagtat gctactagca
     2221 ggttataact ctatgagtaa gaaagaaaaa gcacgatacg ataaaaaaaa attatgtaga
     2281 agttctagca ttgttacttt tattgtctct ataatgctat ttattatggc atttttggga
     2341 tatagaatag agagtggtca aatggacgaa aaaaaaatgg ttaccttttc tataatattt
     2401 ataatagtca tactttccag tgtatttttt aatatcctct actctaacaa aaaatgtaaa
     2461 aaataaatag ttgtaagttg agcagttaat tataaaagat tgactgcttt ttcctgttta
     2521 ttgactactc ttattaaata ttttaacatt tgaaaatcta tatgaaaata atgtatatag
     2581 tataaacttc taataataat tttatctttg tgtttaaagt ctaccatatt ataatttaat
     2641 ataataacag aaaactacta atgacaatta agtaggcttt gataaaatat aataaaacaa
     2701 aaatagatgt acaatgaaat tatatcttat atcaagttta tttttattaa tagcaaaaac
     2761 ttaaattagc ataacatatg acaaactcgc ttaaaataaa aatttttaat ataatttgtt
     2821 ctatagtaca tctatttcga ttagtttaca taattttatt attttataca atattaatca
     2881 tttactagta tcccatttaa tgaaaaagtt ctaggttcag taatttcaac cataactaac
     2941 ttaccaatta aatcatcatt tccaccttcg aaatttacaa gtttattttg tctagttcta
     3001 ccagaaagct tattttcatt atttttactt cttccttcaa ctagaacttc aactattcta
     3061 tttttatatc catcatttat ttctgcagaa atcctattta cagcttctaa tactctatta
     3121 aatctctcat gctttatatc ttctggtatt tgattttcca ttttagcagc aggagttccc
     3181 tgtcttttag aataaataaa tgtaaaagct gaatcatatc taactttttc aactacatct
     3241 aaagtatcca ataaatcttc ttctgtttct cctgggaaac caatcattaa atctgtagaa
     3301 aaagcaatct ctggaacttc ttttttagct ttttctatta tttctaaata atattccttt
     3361 gtataatgtc tattcatttt tttcaaaaga ctactgcttc cacattgtat tggtaaatgt
     3421 aaaaactcac acaccttatc acaatctcta attgcatata ttacttcatc agatatatct
     3481 tttggatgag atgtcataaa tcgtatcctt tcaattcctt ctatatcatt cacttttctt
     3541 aaaagttctg agaatgaaac tggattttca agtgtcttac cataagaatc tacattttgt
     3601 ccaagtaaag ttatttcttt cgttccattt gcaacaagct cttttatctc gttaattata
     3661 tcttcaggag ttctacttct ttctcttcct cttgtgtatg gtactataca atacgtgcag
     3721 aaattattgc atccatacat tatatttaca aatgctttta attcaaattt tctattactt
     3781 ctaagacctt ctattacctc tccatccaca tcccatacat ctactaacat tttgtcagaa
     3841 ttcattgatt ctgtaagcaa ttgtggaaat ttatatagat tatgtgttcc aaatataagg
     3901 tctacatgtt tatatttttt tcttaattcc tctacaacat gtggttgttg catcatacat
     3961 ccacatacag ctattttcat atttggattt tttcctttta ggtgttttaa ttgtcctaaa
     4021 ttaccataca cttttaactc tgcattttct ctaactgcac atgtgttata tattattaaa
     4081 tcactttctt cgaccatcat tgacatttga tatcccatct cttctaacat tgaacataat
     4141 ttttctgaat catgttcatt catttggcat ccaaaggttt gagtaaacac gagttttctc
     4201 tttccagttc tgttgaagta ttcctcattt tgtctgtgta tttgttctat atatttatct
     4261 tgttcttgta ttttctctat aggtattgtt acttgttttc ttttgctcac ttctattcct
     4321 cctagttaat ttcttatatt acacataacc ttaattatat caaataagaa aaatctttta
     4381 aagatattat tatttttcta gtgtgtttta atagtaa
//
LOCUS       DAMKOJ010000160         4386 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000160 DAMKOJ010000000
VERSION     DAMKOJ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.169"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            394..885
                     /locus_tag="PC592_003487"
     CDS             394..885
                     /locus_tag="PC592_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDF4057411.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDSNENSTINIDKA
                     WHAIHFTLTGCPFGGDEDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQEFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKRFIQEASDDGQAVIF
                     FIM"
     gene            933..1085
                     /locus_tag="PC592_003488"
     CDS             933..1085
                     /locus_tag="PC592_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057412.1"
                     /translation="MKTIEKYIKEMIGESISEINSLWKTGESIKINYSKVSSERFEEI
                     IQRVTP"
     gene            1158..1569
                     /locus_tag="PC592_003489"
                     /pseudo
     CDS             1158..1569
                     /locus_tag="PC592_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(1844..2308)
                     /locus_tag="PC592_003490"
     CDS             complement(1844..2308)
                     /locus_tag="PC592_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4057413.1"
                     /translation="MNLNKVKFTEEHAIEVINWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDRRKNFISFINDNKELIGFINLLDEGSSVFFGIGIKPEYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKRQKTYLGDGEFFVMRYQ"
     gene            complement(3320..4147)
                     /locus_tag="PC592_003491"
     CDS             complement(3320..4147)
                     /locus_tag="PC592_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF4057414.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPMMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGTMPTNDNMNNKVSKQK"
BASE COUNT         1613 a          547 c          544 g         1682 t
ORIGIN      
        1 ttcttacata tataattatt ggtatgctta ttaacacttc agaaatcatt atagtttaaa
       61 ttttgagttt attgttatta cttatttaat ttgagcacat tatttatttt tatttgcaac
      121 taataaatag agtatgattt tataatacag tttcttaaat tttttttaaa agtaatagtt
      181 cttatttgta gccaatattg cttatagaac ttattgattc atttaatttt tagaaaaaat
      241 aataatactt acacaataaa cacagaattt tatatagata atataggtat ttaaatttaa
      301 ggtgaaatga tacttttctt aatatatttt attgtaaata agcttgatta taagttaaaa
      361 ttaaaaaaaa cactacttag gaggaatgta attatgggga tgataggatg ctatacaaaa
      421 ataagtgagg agaatgtttt taaattacag caagcagaag aaaatttaca agatttcgtt
      481 tttgaagatt ccaacgaaaa tagtactatt aatattgata aagcatggca tgccattcac
      541 tttactttga caggttgtcc ttttggtgga gatgaagata atatatttag caaactagtg
      601 ctgagtggaa atatacttat ggaaattgat ggagaatttc ctgtcatgtt aattacagct
      661 aatgatgtaa aaaaactatc aaaagcaatg aatagtttgg aagaacaaga gtttagaaaa
      721 agatttaata ttaatgagat gttagaaaac aatatttatc ctgttatgaa tgatgagagt
      781 gaagatgatt tttttgaata tgtatgggca aatctaattg agcttaaaag gtttatacaa
      841 gaagcatctg atgatggaca agctgtaata ttttttataa tgtgataatc actaaaaaat
      901 tgtgaatatt agtgtcatca catatcttag atatgaagac catagaaaaa tatataaaag
      961 aaatgattgg tgaaagtatt agcgaaataa attcactttg gaaaactggt gaaagtataa
     1021 aaataaatta ttctaaagta tcttctgaaa gatttgaaga aataattcaa agagtaacac
     1081 cttaggagga gtgtctacat attttttgac aagttacaaa tatttggagc agtttcagct
     1141 acctataatg aatctatgat gatatagtat cctcaaaatc attatctcaa gttattgtac
     1201 aattaattag gatactaatg tcaattataa gtatagcggt attaatcata ggttttgtaa
     1261 atattttaat atatcttgga ggcgattttt tagtagttga gtatatttgg aaatttcgca
     1321 ttggctatgt ctataggaag tttaggaatg tttttctcaa atttatttaa taatacaatc
     1381 ataggttata tggtatctat gggatattta attttaaata tgatgactaa aggcaagtat
     1441 gttggaaatt tttttataat gtctatgagt caaagtagtt ttgatgagaa atattagttg
     1501 atacttggaa gtattgtgtt gataattgaa tctatcttaa taaaaccaat aaaaaggaag
     1561 attagataat aaaatgaggc ttagataaaa taaaggtaat acaaacaaaa agtacattta
     1621 tgaaatatga atttattttt acatacacaa acctacttat aatctcttta tgcatgtaga
     1681 tagatttata tatcagtagt ataaaataca tatgtatacc gaattttatc aaaagttccc
     1741 aaatttatat ttcaaagacc ccaaagacac ttattgctat gacctacgta catgtatttt
     1801 ttcattttaa tttttatatt agcaatatga ctagtgtcgt aaactattga tacctcataa
     1861 caaaaaattc tccatcccct aaatatgttt tctgtctctt agtctcaact attttaaatc
     1921 cttgagactc ataacatttt acagctctca tgttccaggt tcttacattt aatacaattg
     1981 gtttagtact atatttattt ctacattctt gtaatcctag gctaattatt tctttaccaa
     2041 ttcccattcc gcaatactct ggttttatac caataccaaa gaatacagag cttccttcat
     2101 ctaataagtt tataaaacct atcaattctt tattgtcgtt tataaaactt ataaaatttt
     2161 ttcttctatc ttcttttgct agtgaaaaat tcttcttttt aatttcctcc catggaggta
     2221 gattgtatat tgaatattta ccttcatatt tccaattaat aacttcaata gcatgttctt
     2281 cagtaaattt aactttattt aaattcatat gtcctcctat taaaatattt aaggtaatta
     2341 atggtatttt aaaattttag aaaataagta aaactattta tatttatcca tgaaatcttt
     2401 aaaaatttta ctaacaattc ttgtaccctg tattttttat tggattcaca gaagactata
     2461 aactaatttt gaattacctt ctaattcaaa aacctcacaa tatatgtaac ttcttagctt
     2521 gattaaattc tgttaaatct gtttcttata gatttcttat agttgtataa tcaacatcaa
     2581 tatatttatg tgtattagtt aatttattga ctttaggaac ttattattaa tatgttatat
     2641 ttgcttcaat actccaatag tagggtaaat tgtaggcaaa ttatcaaatg tatatctatc
     2701 catgcttaaa ctttagagat acaataacta ctaaattagt attctagtag ttataaaaaa
     2761 gaatctttaa aaatattaat ttaacttata ttttttaata aattttctaa aatttaatca
     2821 gttaatttaa ttatagctct aaatgatatt ttctacagat agaatttcaa aaagatgtgt
     2881 ataagaacaa gttcacttaa atttttaaaa tcaaataaag ttgaatctct tgattacctt
     2941 gattatttta tgaacttaat atagatgtaa actttactat taaaaaaata cgagatttta
     3001 gataagttaa tgctaattta aataataaga taagaaatat aatatgacat aagagctagg
     3061 aataagataa atataatcaa agaataaggc atgagaataa ttaccaagag aaatcgttac
     3121 tttaatatgt ttatgaatgt tagactatgt tcctaaattg aattttatat atcaaatata
     3181 ataacttaca gaatgtggaa atttttattt aaagaataca cataaacatt tccacactct
     3241 gattttataa taataatcta ataaaattta tagtgacttt ataaactcaa taatgattta
     3301 ataaatattt ataaaacaac tatttttgct tagaaacttt attattcata ttatcattag
     3361 taggcattgt tccaaaactt agtttttcat acattacttg agttggagct agccaaactg
     3421 taccattacc agtaaatgta tttaagaaac cttcaccatt taaagcagaa ccaattaaag
     3481 atttatctga ctttgtaaca gaaaaattaa caccagatgt tcttgctatt gcaaagttac
     3541 catctacctt taattcttca ccatttttca attcatactc tacaatttca ctttgaggaa
     3601 caacacattc cagaacgatt acaccagtac cacttaattc tatttggaag aagccttcac
     3661 caccaagtaa agcagatgag aagttctttt gtgtaaatgc ttttacttct attgtatcag
     3721 agcaacaata gaataatcct ttatcaacaa ttatggaatc attgtcaaga ctcataaata
     3781 aatagtgcct aaaagaaggt tccaaataaa cttctccagt acccttgtat acaggtttca
     3841 tcattgattc attagtaagt gctcctgata ttcctttttt gaaaagacct ccaacaccac
     3901 caatcttagt ttcagaagat atatttcctt tataatagta taatgcacca gcttctgttt
     3961 ttattgatga attatttaat tttatcttaa tttgtctagc tttcaaacca gcttctctag
     4021 caaaatataa tcccattgcc atcattgggc tagaagctcc ctcaagtttt tcaaattcta
     4081 atatctcaaa ttcgcttttg ccatctgatg cattttctaa aatttttact tttttgctta
     4141 aatccataca aatttctccc gactatgtta agatttatct ctaaaatatt ataagatata
     4201 attatatatt acattttttt tgaaaaaatg gctactttat catcaaattt ttaaatattt
     4261 ttaataagtt tttgaaatgt ttagatttaa gttaaattgt ttaagaacat atacttgttt
     4321 caataggtat tttgagtatt atttattgct tttgggtatt atattttatg ggtatgttaa
     4381 aattat
//
LOCUS       DAMKOJ010000161         4374 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000161 DAMKOJ010000000
VERSION     DAMKOJ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.170"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(586..804)
                     /locus_tag="PC592_003492"
     CDS             complement(586..804)
                     /locus_tag="PC592_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057415.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENDI"
     gene            complement(805..1212)
                     /locus_tag="PC592_003493"
     CDS             complement(805..1212)
                     /locus_tag="PC592_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057416.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKLLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(1298..1786)
                     /locus_tag="PC592_003494"
     CDS             complement(1298..1786)
                     /locus_tag="PC592_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HDF4057417.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLYNVKLIKEFV
                     AK"
     gene            complement(1966..3063)
                     /locus_tag="PC592_003495"
     CDS             complement(1966..3063)
                     /locus_tag="PC592_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF4057418.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTVIEEKDREWTKKLNDILSRDDFS
                     NEKLDKIKNLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKPFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEESNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILSHVKYNHIEDYVNCLRLT
                     IDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RVLDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGVEKGIAKGKREERFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKIYNQN"
     gene            complement(3436..3606)
                     /locus_tag="PC592_003496"
     CDS             complement(3436..3606)
                     /locus_tag="PC592_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057419.1"
                     /translation="MDSNNDTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            complement(3778..4221)
                     /locus_tag="PC592_003497"
     CDS             complement(3778..4221)
                     /locus_tag="PC592_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4057420.1"
                     /translation="MIEIKTIEINKKGQIDLLMLADPCEEMIDKYLNKGTMYALYDNE
                     ELICIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMIVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
BASE COUNT         1492 a          700 c          381 g         1801 t
ORIGIN      
        1 ataaaatatt tctaattttc atatagatat tattataaat tttctagttt atggagctat
       61 tcattctata attcacaaat atatattttt taatctatta aactattcat tttctgctta
      121 taagcatgga cttattatct ataagcttgg tttttcatct ataagtcatt tattctttaa
      181 tctatgagct tgatttttca tctataagtc atttattttt taatctatga gcttggtttt
      241 tcatctataa gtcattcatt ttttaatcta tgagcttggt ttttcatcta taagtcattt
      301 attttttaat ctatgagctt gatttttcat ctataaatca ttcatttttt aatctataag
      361 cttggttttt atttataagt tatttattct ctaatctata aggttgcttc ttcatctata
      421 aatcattcat tctttaatcc attagcttgg tttttcatct attaatcatt tattctctaa
      481 tttataagct tggtttttta cctataatta attcattctc taatacataa acttgaattt
      541 tttatctatt aattcattct ctaatgcata agcaatacat gaaatttaaa tatcattttc
      601 ttcaataaat tcaaataact cttctacagt tgtatcaaat accttagcaa tatccattgc
      661 cagttttaaa gaaggattgt agcgaccatt ttctaaatgt acaatagttt cacgtcttac
      721 tcctactgac tttgcaagtt caccttgtgt cataaggttc ttttctctat aggatttaat
      781 ttttgtcttt agtaatactg acacctaatt gtatatcccc tttctgtcaa aatatataaa
      841 taaaattaac ttcaacaagg attgaataaa caaaatgact aataaagaca ttcctatatt
      901 taaatttgac acatttatgt ccaaagttac aagaaatata gatactatag ctacagaaaa
      961 aaacaataat tttattgcaa tatcattaac tcttgatagt atacattttg atgcctcatc
     1021 aattaaatca tcatactttt tattatagac ccactgagct cccatagcta atacccaaat
     1081 aattatagga agatattcaa tactacttcc tttaaaaaaa tacttattta ctaatgtagc
     1141 tccaatacaa taagaaattc ccaatatttc tgaaataagt gttgatttaa taccagtttg
     1201 ttgtttagac atataaaatc ccccttaaaa agttatatat ttataacacc tcttgttata
     1261 aatatataac ttttttgaat aaatttcaat aaaaatatta ttttgcaaca aattctttta
     1321 ttaattttac attatataga ggaactttag atgtcactcc ttgcaatgtc aaatcttcta
     1381 tattaacttc atttaatttt gaacacagtt ctaagtcaaa tattctttcc caacttacct
     1441 tcttttcaat ttgttcatct tcataaagct ctacagtaat atccattaaa ggtaaatgcc
     1501 ataaatcaaa ttctgataat aacacattat cttcacttat ttctatttca agtaaaacac
     1561 ctttttttcc tttttctaaa taaccactac atcttaaatc aggtctcttc gtccaaaccc
     1621 atatcatact atcatcaaat tcatatattc tatttgtcat ttgactatac atccatttgt
     1681 atggaatatc aaagtcttct aatataaaag aataatcatt tgatagatat ttattgtttt
     1741 tattgttgtt ccaaaattct aaagtctgta tagtataaaa tttcatatat aaatcaatcc
     1801 ctttgttttt ctataagaag gagatggttc aaacttttat tttaaatcat ctccttagct
     1861 tatatatctc tttgtatcta ctatagttaa ataacaaggt tttatattaa tttaaattta
     1921 aaagaggaag ctttgtattt atctagtgcc atctcaatta tagtattagt tttgattata
     1981 gattttttca acctctgatt tattcaaatc atctataata tcgcatattt cactcaaatt
     2041 gtatccttta ttttttaatt ttatgatgat attaaatctc tcttctcttt tcccttttgc
     2101 aatacctttt tcaacacctt cttgaaaaat ttcttcttta aaatttctac ttttattcat
     2161 aatatacgca cctctcttta aatttaataa atagtcctca ttactgccta attcttttaa
     2221 tctatcaagt actcttttaa taacataatc cgttttagat agtattctaa tatcgatatg
     2281 agaaggatta tcaataagtt taccccatat tagaactcta tttgctatac aactggattt
     2341 acgaattttt ggaagttcta taaaatataa tgcagtttta ctagagaaaa tatctggatg
     2401 cccatctatc gttaatctca ggcaatttac ataatcttct atatgattat attttacatg
     2461 acttagtata tgtattccaa cagtttttcc aatttcttta tattctttac cttcttctaa
     2521 ctttctacca tgtacacgac taagataata ttcagctctt tccaaataat cctcttcaag
     2581 agctctttgc atctcaatat ttatatgatt actttcttca tcttcagcca aaatatcaag
     2641 tctaggtctt ttctcaccaa tgtaattaat tgttgggtcg gtttcaacct taattattct
     2701 ttttatttga gtgaacggtt tgatattcct attagcatat ggagcatctt tgagaatatc
     2761 atttataaaa tttgcaagta aatcgtaatc attatttaaa gtaaataatg atttaaatac
     2821 ctcatcatac tcaggcttag catacccatc ttcagttaca acttctccaa cattttcact
     2881 agtcaatatt tcttttggaa ttaaattctt gattttatct aatttttcat tagaaaaatc
     2941 atctctacta agtatgtcat ttaatttttt agtccattct ctgtcctttt cttcaattac
     3001 agttctctta tactcttttg atgttttaat aatcttagat ttttcttcta atttttcttt
     3061 catatcaaca cctctttttt attattaccc atttcttcat accaaagtct gcacttctaa
     3121 gtaaaatttg cattattgaa ataagaacat gataaactca tatatcatta ctaaagttaa
     3181 gactttaaag agaatcactt agattacaat agattttaga taactttctt tttaaaacta
     3241 ttgttgataa atgaatgaat ataaaggtat gtattaaaat agagataata atctttttca
     3301 ttgtttaagt aatgaaaata tagtttattt aatacaaaaa agagtgcctt ataaactaaa
     3361 agttcacttc gagacactcc cttacatttt gtttcttaaa cttcacaata ttacacactt
     3421 atttattaat ttaatctatg catacttaac ccaataataa agtacatata tccaactcat
     3481 taagccatga aaaatagccc atggaataga tttccatgca gtataagaaa taatcattgc
     3541 taaacaagaa ccaaaagaaa tacccttttt aacagttgat tttatagtat cattatttga
     3601 atccataatt aatcctccaa aattcaaaat aaacaagtta ttatatatat tatttgaatc
     3661 taatacaata taacagcttc taaataaatt atactcttat tatacataat ttataaatta
     3721 tagttccaat aattatatga ataaattatt tatattaacc taaaaatatt atcctatcta
     3781 aaagttatat gatagataca acatgtcaac acattgtaat tctccctcaa agattggttc
     3841 tggataatta tctacaaaaa agtttttaat tttatgtgaa taaacaaatc caaacttctc
     3901 ataaaaagga actccgcttt cagatgtacc aacaatcatt gatgaatatt ttttactata
     3961 aacatctaaa agatgataaa tcatctttga ggcataaccc atattttgaa aatgctcata
     4021 tgtagcaatg ttttttaatt cacatatttc tttggaaatt tcatttacaa ctgctataca
     4081 aataagttct tcattatcat acaatgcgta catagttcct ttattaagat atttatcaat
     4141 catttcctca catgggtcgg ctaacattaa aaggtcaatt tgaccttttt tatttatttc
     4201 tatagttttt atttctatca taagttctcc accctcactt tattcaaacc ttaatttagc
     4261 aaacttctta cagtacttat ttaattcatt ttgatatata tttttacttt tttaaaatat
     4321 agtgataatt ccctagaata ttaatactaa taataaatta taatatcagc acta
//
LOCUS       DAMKOJ010000162         4362 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000162 DAMKOJ010000000
VERSION     DAMKOJ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4362
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.171"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            54..650
                     /locus_tag="PC592_003498"
     CDS             54..650
                     /locus_tag="PC592_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HDF4057421.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DINREEKINDIYKYLYKCKKIDFIVIDKKEKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKGDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(747..1706)
                     /locus_tag="PC592_003499"
     CDS             complement(747..1706)
                     /locus_tag="PC592_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF4057422.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNENIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDKVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(1740..2471)
                     /locus_tag="PC592_003500"
     CDS             complement(1740..2471)
                     /locus_tag="PC592_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057423.1"
                     /translation="MVRSGFLLENICKKYLVDNKEHLVLDNVSLNISSEEITVILGES
                     GCGKTTLLRILAGLENATTGNVYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVSIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(2464..3234)
                     /locus_tag="PC592_003501"
     CDS             complement(2464..3234)
                     /locus_tag="PC592_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057424.1"
                     /translation="MFEKIHKKFKGYYIFFIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVVFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SRKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(3319..3999)
                     /locus_tag="PC592_003502"
     CDS             complement(3319..3999)
                     /locus_tag="PC592_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014903004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF4057425.1"
                     /translation="MCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPSNGGGLGRALL
                     GHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESENLLAFSEQLN
                     YSVKLIGSGVISQKGLFTTHLANKTGQNQDVAIITDGNPLILEGPCCVDPDALVAWTG
                     REPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKTDSTPSDRMSS
                     GGLRIGID"
BASE COUNT         1466 a          768 c          492 g         1636 t
ORIGIN      
        1 tagtataatc taattacttg atattaattt tcatttgaag gaggttatct tttatgtctt
       61 gctgtaattc acaattttgt tgtaaaaaca aaattgaatc atcatatata aaatggcttt
      121 tagaagtttt aggtccagtt ttcttaggct ctaaacctgc tgaaataata aatatttcat
      181 ttactgatat aaatagagag gaaaaaatta atgatattta caaataccta tataaatgta
      241 agaaaataga ttttatagtt attgataaga aagaaaaagg attaaaaata ttatttgtaa
      301 acaaaaaggc attatcagaa aaattaaaat gtaaaaaaac agtaaacttt ttaaagtttt
      361 taggatacaa acaaaatacg aatgttaatg cttatttaga acatttagta gataaactta
      421 agggtgatgt ttttcctgat gaaataggta tttttttagg atatcctctt aaagatgtga
      481 ttggatttat gggatatagt aattatgaag tttctatgat taaatattgg aaagtttatg
      541 gtgacacaaa acaatcagag gacacatatt caaagttttt acttcaccgt aagaaaatga
      601 gaaaattact agactacata agtgtagata aaatagtaag ttgtttttaa tagtgttttg
      661 tatgataata aaaatacacc ctcttttaat atacagttta cataataagt aagggtgtat
      721 tttctacttt aatattttaa aatattctaa ttctgattgt acaacatatc tttaatattt
      781 attttctttt gttgcattcc attagacatc aaaaattcct gtgtatcttc taattctttt
      841 atatccttat ccgttatttt agaactaaag tcataccaag aatacatttc ttttgtttca
      901 tctaaagata aaccaacttc tttagataca acatccatca ctttgtcctt attttcattc
      961 atatatttta aagtttcttc atgaaccttc ataaatcttt ttactaattc aggatatttt
     1021 tcagcaaagt catcacttac agcagtaact attattccac ttactagacc ttctccattt
     1081 acaatcattt tggcacctga atttatcgtt ttcaatgcca ctggacctgc aagcattgct
     1141 acatcagcac ttttactttc taatgcagaa gcagcactag gaatatccat atttacatat
     1201 tcaacatcat ctatagtata gccttcttta gcaagtgcag caatcaacag ttgatgaagt
     1261 atagtccctt ttggccctac aattttctta ccttttaagt cttttataga ttttatattt
     1321 tcattattag ttataagcat atatcctttt ggtgaacgac tataaatatt cgtaatttta
     1381 agaccaacac catttgacgc agctattatt gcagatgttc ctcccaatgc atgtaaaaag
     1441 tctagctcac ctgctgctag tgcttgagtt tgctctggtc ctgttgtcaa ttcatggaag
     1501 ttgactttta tattgtcctt tttaaattcc tttccaaata aatcatcctt tttttctaat
     1561 atactaggaa cattaagtgg tgattttaca taagttaaat ttatttcctt aggtaaacta
     1621 gcctcttttt ttgcaggttc atctttctta tcatttgttg ttgagcatcc tacagtccca
     1681 accaacacca ttattaaaga tgtcattact gctaaaatct ttttgtttct tttaatcaat
     1741 taaaactccc ccaattccct taatatttct tttttcaagt ttatataata gtttttagtt
     1801 aaatctctat tatattcatc ttcgacacta aactgtttaa tccttttatt tttactaaaa
     1861 acaattattt tctttgctat ttccatagct tcttcaatat tgtgagttac aaatactaca
     1921 ccttttttag tatttttatg gatacttaca acttcttttt gcatttttct tcttgtgaag
     1981 taatctagtg ctgcaaatgg ttcgtccatc agcaaaatat ctggattgaa agaaagtgct
     2041 cttgctatac ttactctgtg agccattcct cctgataatt catttggata tgagttttta
     2101 aatttttcaa gcttcatcat ttttaaatac ttgtctaaat caactttatt tctattatcc
     2161 ttttcagtat gtaaaagtat attttcactt acattcagcc atggcataag tctactttct
     2221 tgaaatacca ttcctacttt tggagtacat tttttatcat tattaaaaaa atatacgttt
     2281 ccagtagtag cattttcaag ccctgctaaa attctaagta gtgtcgtctt cccacatcca
     2341 ctttcgccta atataacagt tatctcttca ctagatatat ttaaagacac attatcaaga
     2401 actaaatgct ctttattatc aaccaaatat ttcttacata tattctctag caaaaatcca
     2461 cttctaacca tttaaatcaa cctgcttccc tttgctaaat tttgttatta tctttgaaaa
     2521 cagataatct gaaagtatgc ctaaaaatcc aataacaaaa attcctacca agacaacatc
     2581 agttctagac atatcttttc catcagaaat caaatatcct aatcctgaag aagctgcaat
     2641 aagctctgct ccaattatag ccctgaaact atacccaagc cctaagctaa gtccaacaac
     2701 aatatccagc atagaattag gaattattat tttataaaaa attctcttcc tagataaatt
     2761 aaaagattta cctacttcta ttaatttatt gtcacaattt tttatgcctt tcaatgtatt
     2821 taaaaatatt ggaaaaaagg atgccaaaat aataattata attttagatt cttcacctat
     2881 accaaaccat aaaataagca ttggcaccaa agctagtgga ggtgtacttc gcataaactc
     2941 aaagagtggc ttgaaatatt catacatttt tttatttact ccaaatacaa ctccaagtgg
     3001 tatagccatc aatgaactta ttaaaaaacc tatcaatatt cttcttacac tggcataaac
     3061 atttaagaaa atagaaccat catatatcat tttaatgaaa gtatctaaaa ctatttcagg
     3121 aggaggcaga atatagctac tccatatacc cagaacgcat actatcttcc ataaaattaa
     3181 aattataaaa aaaatataat atcctttaaa ctttttatga attttctcaa acatataaaa
     3241 ctccttttaa catatctacc cctaataccc tttttatttt ttaatatcct aaataataac
     3301 taatctatat cataaaattt aatctatgcc aatccttaat ccacctgagc tcattctatc
     3361 agaaggagta gagtctgttt ttaaaccaga caatctttca gatggctgta taatgactat
     3421 ttgtccaggt tcaacaaatt ccatatgata agattctcct gaagtctgac cgataaaagt
     3481 cttccatgac aattttgaca ctttaggata tggttctctt ccagtccaag ctactaatgc
     3541 atctgggtca acacaacagg gtccttcaag tattaaaggg ttgccatctg ttattatagc
     3601 aacatcttga ttttgacctg ttttatttgc taaatgtgta gtaaaaagac ctttttgaga
     3661 tattacacct gaaccaatca attttacact gtaatttaat tgttcagaaa acgccaataa
     3721 gttttcactc tcaacataaa tggagtcacc tgggtcaatt gatattacat ctacatgata
     3781 agcattttga gctaggtaaa tttcaccttc accttcaaca accattattg gcatttgttc
     3841 tcctgtcaat gacctctgaa catgacctaa taatgctctt cccaagccac caccattact
     3901 tggacctaac agcaattttt caaaattaaa atttccttta aaagctacca tagcaccttt
     3961 ttttgcaaaa aatttaccac ttcctcttgc tatacacata agctcatttg tcacctgaac
     4021 ctcccatgaa taaagtcaca gagttcctgc ttcacagaat tttgcatact aaaatatgtc
     4081 ttactaattc tccacagtct atccccataa tttctacggt tcttacataa gctatttatt
     4141 ttgaattgtt attagtctta atccttcttt taatatattt agacttactt taatgatttt
     4201 atcatattta atatactata taatgctgtt gggaacaatt tattcatcat ctatcataat
     4261 attaacaaat gtaattattt aaaacaatta ttcgaaggtt ttatatttat ttttaaataa
     4321 catatttaag aaccgtaagt cttaactttt atcatttttg ag
//
LOCUS       DAMKOJ010000163         4273 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.172, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000163 DAMKOJ010000000
VERSION     DAMKOJ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.172"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            351..2450
                     /gene="nrdE"
                     /locus_tag="PC592_003503"
     CDS             351..2450
                     /gene="nrdE"
                     /locus_tag="PC592_003503"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDF4057426.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDREALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSMDFIKNIYEIIDKQKFEFQSYMSANKFYQNYALK
                     SNDGKKILETYNDKVLIVALTLGNGNKDLVLNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMNKWYDKLVNDNDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDIGIIKMSNLCCEIFQYQTHSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIEKNQT
                     FEGFDKSEYAKGRNSKVLSKYYEQSYLPKSEKVKALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAIAPTQSISYVQNSTSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNILYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            2463..3434
                     /gene="nrdF"
                     /locus_tag="PC592_003504"
     CDS             2463..3434
                     /gene="nrdF"
                     /locus_tag="PC592_003504"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDF4057427.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKIWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNSEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEILEEKMYSILYRLMENEIEYTNIIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            3511..4137
                     /locus_tag="PC592_003505"
     CDS             3511..4137
                     /locus_tag="PC592_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF4057428.1"
                     /translation="MKYEWRKRDKELYLPKKNPAIIEVPEQKFIMLKGNGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKCLDVLIKEDLIYT
                     LMIHQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYIHHEIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         1715 a          456 c          783 g         1319 t
ORIGIN      
        1 aatatagtat aatatatttt taggctattt agagatgatt tgaaaattta aatatatcat
       61 aataagctta tattgtttta tatttgagtt gataaaaatt tctttaaaca aaaataatgt
      121 caggtataca ataataaaag tttagatata aaaaaatttg tgtatatact atatgtagta
      181 tataatagat aaagcactga ctatatgtag tgcttttgtt tttgaaaaat acttattata
      241 tcctataatt atagattagt tttgggattt caactaataa gtacaaaaag aaataataag
      301 caaattaaat gaaattatag cacaagatta tgttaaaagg acggtaaata atgaattgga
      361 tagagcttaa caatcaagtg ataattaaaa atgaacaagg taagtatcag ttggaaaagg
      421 atagggaagc cttaagtagt tacatagaag aatttataca accaaagtta agaaaattta
      481 ataacctaga agaaagattg aagtatttaa tagatgaagg ttattattca aaagaagtaa
      541 taaatcagta tagcatggac tttattaaaa atatatatga gattattgat aaacagaagt
      601 ttgaatttca atcttatatg agtgcaaata agttttatca aaattatgca ttaaagagca
      661 atgatggaaa gaaaatatta gaaacatata atgataaagt gttaattgta gcattgacat
      721 tgggaaatgg caataaagac ttagttttaa acttggcaga taaaatagta aaacaagaat
      781 ttcaaccagc tacacctact tttttaaatg ctgggagaaa aagagctgga gaaatggtat
      841 catgtttttt actatctgta gaagatagta cagaaggtat atcgtatgct atatcttcat
      901 caaatcactt atcaaagatt ggtggaggag ttgcactgaa tttatctaaa cttagagcat
      961 ctggagaatc tatcaaagat atagaaggtg ctgctggagg tgttgttgga gtagctaaaa
     1021 tgttagaaca atcatttagt tatttcaatc aaatgggagc tagacaaggt tctggtgcag
     1081 tgtaccttac tgtattccat cctgattttg aattattgat ggatactaaa aagataaatg
     1141 cagatgaaaa aataaggctt gctacattat cattaggagc tataatccca gataaattta
     1201 tggagttggc agaaaaaaat gaagtagcat atgcatttta tcctcatact gtgtataaga
     1261 aatatggcgt ttctcttgat gagatagaaa tgaataagtg gtatgataaa ttggttaatg
     1321 ataatgatat aagaaaaaaa gaaataaatc ctaggcagat gttgacaaaa atagcacaga
     1381 tgcaacaaga aagtggatat ccatatgtag tgtacataga tacagctaat agagaacata
     1441 cattaaaaga tattggaatt atcaagatgt ctaacttatg ttgtgagata tttcaatatc
     1501 aaacacattc agaaatagag gggtatggag gcaaaaatga atggggacaa gatataagtt
     1561 gtaatctggg ttctttaaat atagccaatg tgatggataa taaaactata gaaagtacag
     1621 ttgaaacagc aataagagca ttgtcatttg tagcagatag cacagatata aaaccagtgc
     1681 caacagtaag caacagtaac agcaagtctc actccatagg actaggagct atgaatttac
     1741 atggatactt agtaagagaa aatattttat acacttcaga tgatgctata gatttttcta
     1801 atgtattttt tgcaatggtt agatactatt caattaaagc ttctatgaaa atagctatag
     1861 aaaaaaatca aacttttgaa gggtttgata aatcagaata tgctaaggga agaaatagca
     1921 aggttttatc aaaatactat gaacaatctt atctgcctaa gtcggaaaag gtaaaagcgt
     1981 tatttgaagg gatttatata ccaacaaaag aagactggac aaaattatta gatgaggtaa
     2041 aagaaaaagg gatatataat gcatatttaa tggctatagc accaacccaa agcattagtt
     2101 atgttcaaaa ttctacatca agtataatgc caattactga gccagtagaa gtaaggacat
     2161 atggagattc tactacaata tatccaatgc catttttaac aaatgataat atattgtatt
     2221 atcaatcagc atataggatg gatatgagaa aggttataga tttagtggca acagttcaaa
     2281 atcatgttga ccaaggtata tcaacaacac tatttgttac agatgaaaag acaactagag
     2341 atatagctag acattacata tatgcctata aaaaaggttt gaaaagttta tattacacaa
     2401 gaacaaagat gacaagagac actcatgagt gtctagtgtg ttcagtatag ggagagaaat
     2461 atatgacatt taatttacat aaaatacata atgcagttaa ctggaataga gaggaagatg
     2521 gatttacaca ggctttttgg gaacaaaatg taaaacaatt ttggcttcct gaagaaatat
     2581 ctgtttctaa agacataaag atatggaatg aactaagtaa taaagaaaag gaattatata
     2641 aaaaagtatt gggtggttta acattattag atacaaaaca ggggaataat ggaataccat
     2701 ctatgatgag tttaacagaa aacttacaaa gaaaagctgt cttgtctttt atggggacta
     2761 tggaagaaat acatgcaaaa agttattctt ctatatttat gactctactt tctaattcgg
     2821 aaatagatga actatttgaa tggatagaaa cagaaccaac attacaaaga aaggcagatt
     2881 tagttttagc tcaatacgaa aatactacaa atcaagaggg attatactta tcaatggtta
     2941 caagtgtatt tttagagagt ttcttgtttt attcaggatt cttttatcca ttgtatctat
     3001 ctggtcaagg aaagatggta gctagtggag aaataatatc gcttattctt agagatgagt
     3061 ctttacatgg taagtacata ggattgcttg cacaagaaat atacgattca tttgataaaa
     3121 tggataagga gatattagaa gagaagatgt attctatact ttatagactt atggagaatg
     3181 agatagagta tacaaatatt atatacagag aaagtggtct tgaaaaagag gttgtgaatt
     3241 ttttaaaata caatgcgaat agagccttag aaaatctagg gtttgagaag ttatatactg
     3301 tagatgctat aaatccaatt gtattaaatg gtcttagcac tgaaactaaa acacatgatt
     3361 tcttttcgac taagggtaat ggataccaaa aaggagtgta tgaggaatta gaggatgaag
     3421 attttataat ataatttata attatgacat aatgttgtca cttttagcat gataatatca
     3481 atgtatgaaa tatatgtgga ggtatttttt atgaaatatg aatggagaaa aagagataaa
     3541 gagctatatt tacctaaaaa gaatcctgca ataattgaag taccagaaca gaaatttatc
     3601 atgttaaaag ggaatggaga cccaaattct aaagaattta ctgaagcaat aggagtactt
     3661 tattctttgg catatgcaat aaaaaccatg cctaaaaagg gaattgtccc agaagggtat
     3721 tttgactata ctgtttttcc tttagaaggc atatgggata aaggagaaaa aagcaaatgt
     3781 ttagatgtac ttattaaaga agatttaatt tatactctaa tgatacatca gccagatttt
     3841 gttacacaag acctgttgga taaagctact gatatagtaa agaagaagaa acctcataat
     3901 cttcttgaaa aagttagatt tgggtctatt aatgaaggtc tatgtgttca aatgcttcat
     3961 ataggttcat atgataatga accagaaagc tttgatatta tgaacgaatt ttgtaaaaaa
     4021 aataaactta taagaaaatc ttacatacat catgagattt atataagtga tgctagaaaa
     4081 gtatcgcccg aatcattgaa gacggtttta cgttttgaag tagaaaggga agtataaata
     4141 ttttgaataa tttataagag ttataaaaag tgaagtctgt tgagacttca ttttttgatg
     4201 cagttttaaa attaaatttg attaaaaaat agctatgcac acttgtgact ttagtcatga
     4261 gttagtagct aaa
//
LOCUS       DAMKOJ010000164         4200 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000164 DAMKOJ010000000
VERSION     DAMKOJ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4200
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.173"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(811..1032)
                     /locus_tag="PC592_003506"
     CDS             complement(811..1032)
                     /locus_tag="PC592_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057429.1"
                     /translation="MILKKVIISGICIFTCLLASSIPTFANELQYENIEQYATIEYAN
                     DSMERMSYIKSGSCGLTISNGIATIRSSV"
     gene            complement(1103..1816)
                     /locus_tag="PC592_003507"
     CDS             complement(1103..1816)
                     /locus_tag="PC592_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HDF4057430.1"
                     /translation="MEILSNKKDNFDITDDMLQEIIPIATKIILDDLPSDDELNHIFS
                     KSFERKMKKLIKQQKRSSLTNKIIFYSKRTAIVFLIVLASLFTITMSSEALRTRLYEL
                     VIRVYEDLTSFVFSTNDGEESLNLKIIEPKYIPNDFKEVDRVDNFIINYKNKNNIEIN
                     YMFCEISSNSIILDTENAKVENISINGNRAKYIEKGTSIQLFWNDKNCIYLLSTDCYK
                     EDLLKKYKNELIKMGKSIK"
     gene            complement(1800..2342)
                     /locus_tag="PC592_003508"
     CDS             complement(1800..2342)
                     /locus_tag="PC592_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4057431.1"
                     /translation="MLIYLAMLELEEDKIKFEKIYEKYRQIMFYVANKILKDDHLSED
                     AVHNAFLRIIKNIDKIDEVDSPRTKAFIVIIVERIAIDFYRKRKREKVSDIEEEYKNR
                     EVNFSIEDKVCESNLTIALAKLNESYFQVLSLKFQYGFSNKEIANVLNLGEENVYKRI
                     QRARKKLKEILEEMEDGNIE"
     gene            complement(2589..2771)
                     /locus_tag="PC592_003509"
     CDS             complement(2589..2771)
                     /locus_tag="PC592_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057432.1"
                     /translation="MKKRFYKVFLKTIPNLIIVILSLALSFYTNTFDIYLKILLLIPL
                     AYVLLFIYYYIKTKKD"
     gene            complement(2799..3410)
                     /locus_tag="PC592_003510"
     CDS             complement(2799..3410)
                     /locus_tag="PC592_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057433.1"
                     /translation="MKNKRINSILSIIMTTVIISLSFVTTANSMEKTESDNNIKIELS
                     DKEVEELHNYWPEDKIFSDEKIDEILIKTGQFTQEELDKINQEVDDYAKKVNQNSRVK
                     YINGYNKYRTFVKNGKKYLYIYVSGKTLKKIKAGADLSSTFGGFLPKIWVGLAVVVIG
                     KIITTNMNGINTNYGIVLSYIEDKWNFQGATYTYRYDHWFYQT"
     gene            3546..3740
                     /locus_tag="PC592_003511"
     CDS             3546..3740
                     /locus_tag="PC592_003511"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF4057434.1"
                     /translation="MQDLCKYTQNLSLKTTNQFLAAFLALVFSNNKVTNKVRQFLDLT
                     LKLIPYALVSTEYSEEKMNL"
BASE COUNT         1490 a          606 c          381 g         1723 t
ORIGIN      
        1 attttataag ctttttaaga gactgtaagt aaatttatgt aaaaataaat ttacttacag
       61 tctcgttatt tattagtata aatatttaca tgaaataact taaaacctca aaatatgtcc
      121 accttatacg ctatacttaa tattaagatt tttatactct ttataaagta ctgaaattta
      181 tagataaagt tttaaattaa tattaaagaa aataataact tattttttag gtcctttgtt
      241 cttatttctt ttgatatact cttttgctac tttatcaaat cgcccaagat aatccataaa
      301 aacatcacca gaagttaatt ttcttgaagt ataagaattt attactattt tcatttcaat
      361 cctcccatga attttattga tatatagtat tatagcgtgc ttctgattgt attcggattt
      421 ttttgaaatt tattaataac ttataagtac tttattcctt tctaaaaata tcaatcacaa
      481 gtataagtat tattattatt aataataaat tagcagactg gattaatata attggccatt
      541 caaaatatat tatttatagt cacctcatct tatatgtaca atatattttt attatctttt
      601 tttactactt attatatttt tgatttcaga gttagctttt accatagcat gaactctgta
      661 atatccttta ctgatttttt gttttttaga aattgaacaa gattattttc ttgaagcatt
      721 ccatgtatta attgtttacc atgtctttct attattatca ctcttttgta gtcttacaac
      781 tattgatgta ctttttacat tcactcttcc ctatacagaa cttcttatgg ttgcaattcc
      841 attagaaata gttaagccac aactaccaga ttttatataa ctcattcttt ccatagaatc
      901 atttgcatat tctatagttg catattgttc aatattttca tattgtaatt cattggcaaa
      961 tgtgggtatt gaagatgcca acaaacatgt gaaaatacat ataccactta taattacttt
     1021 tttcagaatc ataaaaaaca cctcctcatt cttttgtata actataaaac gaataaagag
     1081 atgctttctg gacactagaa aattatttta tactttttcc catttttatt aattcatttt
     1141 tgtatttttt caaaagatct tctttatagc aatcagtact taataagtat atacaattct
     1201 tatcattcca aaataactga atagaagttc ctttttctat atattttgct ctattaccat
     1261 ttattgatat attttcgacc ttagcatttt ctgtatctaa tataatagaa tttgaactta
     1321 tttcacaaaa catatagttt atttcaatgt tatttttatt cttataatta ataataaagt
     1381 tatccaccct atctacttct ttaaaatcat ttggaatata tttaggttct ataatcttaa
     1441 gatttaaact ttcttctcca tcattagttg aaaaaacaaa agaagtcaaa tcttcatata
     1501 ctcttattac caattcatat aaacgtgtac gtaatgcttc gctactcata gtaatagtaa
     1561 ataaactagc taaaactatt aaaaatacaa tagctgttcg ctttgaataa aaaataatct
     1621 tatttgtaag actacttctt ttctgctgct taatgagctt tttcatcttt cgctcaaaac
     1681 tttttgaaaa aatatgattt aattcatcat ctgaaggaag gtcatcaaga ataatttttg
     1741 tcgcgattgg gataatttct tgaagcatat catccgtaat atcaaaatta tcttttttat
     1801 tactcaatat ttccatcctc catttcttct aatatttctt ttaatttttt tctagcacgc
     1861 tgaatccttt tatatacatt ctcctctcct aaatttaata catttgctat ttctttattt
     1921 gaaaaaccat actggaattt taaagaaagt acttgaaagt aactttcatt aagttttgca
     1981 agagctatag ttaaattact ttcacatacc ttatcttcta tagaaaaatt tacctctcta
     2041 tttttatatt cttcctcaat atcagatacc ttttcccttt ttctctttct gtaaaagtct
     2101 atagcaatcc tttctactat tataacgata aaagccttcg ttcttggact atctacctca
     2161 tcaattttat ctatattttt aattattctt aaaaaagcat tatgtactgc atcctctgat
     2221 aaatgatcat cctttaatat tttattggcc acataaaaca ttatttgtct atacttttca
     2281 tatatctttt caaactttat tttatcttct tcgagttcaa gcatagctaa ataaattaac
     2341 atttagaatt cctccaatat aaaaattctg aattaatatt ttaaagttca attataacat
     2401 aaatatataa ttaactctac ttaaatagaa tataattatg cttaacaagc tttttaaata
     2461 tacctagtaa aaaggccctt caaatccatt ttggggatta taagggcctt aactttacaa
     2521 ctaattctca aagttaaact tttaaattaa ttattttcgt atatatctaa ttccataaaa
     2581 aataaaaatt aatccttttt tgttttgatg taatagtata taaacaaaag tacatatgct
     2641 aaaggtatta aaagcaatat ttttaaataa atatcaaatg tattagtata aaatgataat
     2701 gcaagtgata atatcacaat tatcaggttt ggaattgttt ttaaaaaaac cttatagaat
     2761 ctttttttca tattattcct cctaaaaaag catgtctttt aagtttgata gaaccaatgg
     2821 tcatatctat aagtatatgt tgcaccttgg aaattccact tatcctctat gtatgataaa
     2881 acaatcccat aattagtatt tataccattc atattagttg ttattatctt tcctataact
     2941 actacagcaa gacctaccca aatttttggc aaaaaacctc caaaagtaga tgaaaggtct
     3001 gctccagctt ttattttctt taaagtctta ccacttacat aaatatataa atatttctta
     3061 ccatttttga caaaggttct gtacttgtta tatccattta tatactttac acgagaattt
     3121 tgattgactt tcttagcata atcatcaact tcttgattaa ttttatccaa ttcttcttga
     3181 gtaaattgac cagttttaat taatatttca tcaatttttt catctgaaaa aattttatct
     3241 tcaggccaat aattatgcaa ctcctctact tctttatcag acaactctat ttttatatta
     3301 ttatctgatt ctgttttttc cattgaattt gctgtagtaa caaatgataa agatattatc
     3361 acagttgtca ttattatgga taaaatgcta ttaattcttt tattcttcat ttaaatcctc
     3421 ctaactataa taaatttata aaccttgtac atatataacg tatctaaact cgattattgg
     3481 acaaaaattt taaaaatatt tatattttta aaattaaatc ttctagaaac tttaaatgta
     3541 aatggatgca agatttatgt aagtatacac aaaatttatc attaaaaact actaatcaat
     3601 ttctagctgc tttcttggca ttagtatttt ctaataataa agtaacaaat aaggttagac
     3661 aatttttaga cttaacatta aaactaatac cttatgccct tgtatctaca gaatatagcg
     3721 aagaaaaaat gaacttatag atagatttga taaaaagaaa atacatataa atatataact
     3781 tttagtgatg taaaaaaata tataataaaa atgcccttaa aatctatttt ttggatttta
     3841 agggcattaa ctttatctag aattagtaaa tttctatatc ataaaatttt tttaattaat
     3901 acattatttt gctataaaac attattcaac tatctatttt caataaaatc taaaattgat
     3961 gaggtgtgta gtaagtaaaa aaaatttata attattatta taaatttttt tgctctaatt
     4021 gaaagcaata attctgataa aaaatgtagt taatataaat aattgtgtaa accgtaagat
     4081 aatagataac gattaaattc aataatactt taaaacttaa tgtaattcta atcctattta
     4141 tgatatttgt ttgtatttat tctatttttc atgaaagtta taattatatc tactccaaca
//
LOCUS       DAMKOJ010000165         3918 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000165 DAMKOJ010000000
VERSION     DAMKOJ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3918
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.174"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            134..1789
                     /gene="ilvD"
                     /locus_tag="PC592_003512"
     CDS             134..1789
                     /gene="ilvD"
                     /locus_tag="PC592_003512"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDF4057435.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSTM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGNTIGENIRDCKIENEDVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFSKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIEKRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            2130..2756
                     /locus_tag="PC592_003513"
     CDS             2130..2756
                     /locus_tag="PC592_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4057436.1"
                     /translation="MNREEKSKNSKEKIIQSAFLLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLENLVADNTLTANEKIIKLVVHSANDYTRRK
                     MLHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPQELAGMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDECGIQKFKDLFK"
     gene            2785..3597
                     /locus_tag="PC592_003514"
     CDS             2785..3597
                     /locus_tag="PC592_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4057437.1"
                     /translation="MFYNAKSCQMMIDSNTVNYIEFGSGKKILIILPGLGDGLSPLHG
                     KIQAIAFAFRYKRFAKDYKVYMFSRKNQITEKYSTRDMAKDQADIIKKLGIMKAKVMG
                     VSQGGMIAQYLAIDYPDLVEKLVLTVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDV
                     ANKSYSEKYLKKYRLFIPLLGKVGKPKDFNRFIIQATSCIEHNSFSELNKITCPTLII
                     GGANDKIVGNKASFHLAEKIKRSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
BASE COUNT         1526 a          440 c          726 g         1226 t
ORIGIN      
        1 tattgataaa aaatcgtaat aaattttcat tagtatatgc taatattttt ttacaatttt
       61 cgtaattaat taatagaaaa atatattata ataatattat gaaaatttaa aaaagtaaga
      121 aagaggtaat attatgagaa gtgatataaa aaaaggaata gaaggagctc caaagagagc
      181 gttaatgtat ggaatgggtc ttactaaaga agaaattgaa agaccattaa taggtatagt
      241 aaatgcacaa aatgaggtga ttcctggtca cctacatctt gatgaaatag cagaagccgc
      301 aaaaaatgga gtaagaatga gtggtggttt gccattagaa tttcctgcta taggggtatg
      361 tgatggtata gctatggggc atgtcggaat gaattattcc cttgcttcaa gagaattaat
      421 agcagattca atagaagcta tggctatggc acatggtttt gatgctttgg tacttatacc
      481 taattgtgac aagatagtgc caggtatgtt aatggcagct gcaagactta atataccaag
      541 tattgttgtg agtggaggtc ctatgcttcc aggtaaaaaa aatggaaaag tatacgattt
      601 taactctaca atggagggtg ttggagcatg taaagatgga acagtaagtg aagaagaatt
      661 agaagagtta gctatgaact cttgtccggg atgtggttca tgttctggtc ttttcacagc
      721 aaatagcatg aattgtttaa cagaagcttt aggcatgggt ataccatata atggtactgc
      781 tgcgtcacat tctggagaaa gaaaaagaat agcaaaatat gcaggtatgt atgttatgga
      841 gttacttaag aatgacataa aacctagaga tattttaacg atagatgctt ttaaaaatgc
      901 tatagctgtg gatatggcaa tggctggttc tacaaataca gtacttcact tacctgcaat
      961 agcttatgaa tcaggaatag agcttaactt agattttttt gatgaaataa gtgaaaaaac
     1021 tccttgttta acaaaattaa gtccaagtgg aaaacatcat attgaagatt tacatatggc
     1081 aggaggaata ccagctataa tgaacgaact ttcaaaaata aatggaataa atttagattg
     1141 taaaactgta acgggcaata ctatagggga aaatataaga gattgtaaaa tagaaaatga
     1201 agatgtaata catacattaa agaatccata tagtaaccaa ggtgggcttg caatattgaa
     1261 aggaaatctt gctctaaatg gagctgttgt aaaaaagtca gcagttgcag aagaaatgtt
     1321 agttcatgaa ggaccagcaa gggtttttaa ttcagaagaa gaagctgtaa atgctatttt
     1381 tagtaaaaaa ataaacaaag gtgatgttat agttataaga tatgaaggtc caaagggcgg
     1441 tccaggaatg aaagaaatgt tgtctcctac atcagcagtt gcaggaatgg gacttgataa
     1501 acatgtggca cttcttactg atggtcgttt ttcaggagca actagaggag catctatagg
     1561 tcatatttct ccagaagcta tggaaggtgg cttaattgga ctagttgaag aaggagatat
     1621 aatttctata aacataccag acaaaaaatt agaattaaaa gtggatgaag ttgaaataga
     1681 aaagagaaaa ttaaaattta aacctttaga accgaaaata aagcatggat acttaagtag
     1741 atatgctaaa ttggtaacat cagcaaatac aggagcagtt ttaaaatagt aaactatatt
     1801 tatgcaaatt agaaaaaatt aagaaaatat taattggata tcttaggtgt tatagcacta
     1861 atgagatatc ctttttattt aaaataaaaa cacagcaaaa tcttgattat ttcttaaagt
     1921 aatgcatctc tattaaagga atatgagtat aacatatgga tatatcttgt caacattgtt
     1981 gaggtaatac aactttttaa agggctgatg cagactaatt ttcgttctcc ctaaactatg
     2041 aagaaattaa aactcagcta attcttgaca gaataaatat taaaatacat aatgaaaaac
     2101 aaacagacag tctgtttatg gaggatgata tgaatagaga agaaaaaagt aaaaatagta
     2161 aagaaaaaat tatccaatcg gcatttttgc tgttttcatc taaaggatat gattcaacat
     2221 ctacacaaga tattatcaat ttatctggtc tatccagagg tgcaatgtat catcacttta
     2281 aaactaaaga agatatactt agaagtgtca caaaagaact ttattcacaa atgaataatt
     2341 ttttagaaaa tcttgttgct gataataccc ttacagcaaa tgaaaaaata ataaaattgg
     2401 ttgttcatag tgcgaatgat tatacacgta gaaaaatgct acattgtagc tggttagaaa
     2461 aaataccatt tgctttaata gaggaagttc gtaatctcaa taatgtagtt gcacccaata
     2521 ttgctaagat aattaaacaa ggtgttgaaa ataaagaatt ttcttgtgaa tatccacaag
     2581 aattagctgg aatgctcgtt tttagtattg atattttact tgaccctgta ttatttaaac
     2641 gtgaatacag tgaagtatgt aataggttgg attttttatt gtttatgtta aaaaaaatgg
     2701 atattcctct aattgatgag tgtggtattc aaaaatttaa ggatttattt aaataatgat
     2761 agtaataaaa gtgaggaata gactatgttt tataatgcaa aaagttgtca aatgatgata
     2821 gacagtaata cagtgaacta tattgagttt ggtagtggta agaagattct aattatttta
     2881 ccaggattag gggatggttt atctccttta catggaaaaa tacaggcaat tgcttttgct
     2941 tttagatata agcgatttgc aaaagattat aaggtttata tgttcagtag aaaaaatcaa
     3001 attacagaaa aatattccac aagggatatg gctaaagatc aagcagatat aattaaaaaa
     3061 cttggaatta tgaaagcgaa agtaatgggt gtttctcaag gcggaatgat agctcaatat
     3121 ctggcaattg attatcctga tttagttgag aaacttgtgt taacagttac ttcttctaaa
     3181 caaaatgata ccatccaaaa cgttatttgt agttggattg atatggctaa gaaacagaat
     3241 tacaatgatt taatgattga cgtagcaaat aaatcttatt ctgaaaaata tttaaaaaaa
     3301 tatagattat ttattcctct tttaggaaaa gtaggtaaac caaaggattt caatagattt
     3361 attattcaag cgacttcttg catagaacat aattcctttt cagaattaaa taaaataacg
     3421 tgtccaaccc taatcatagg tggtgctaat gataaaattg ttggaaataa ggcttctttt
     3481 catttagcag aaaaaattaa aagaagcgaa atatttatct atgagggatt gggacacgct
     3541 acatatgaag aagcacagga tttcaacgaa agagttttag agtttttaaa taagtaaata
     3601 tatttgttaa aaatatctat gccaatgttg ggaatttaat atggaaaatg gaaacatgaa
     3661 aaggcactgg actggtactt tcaatatacc tagccaattt cttatgtatt atctactata
     3721 aatgtaaata taattttaat atgcttatgt gttggtgtat tagtaaaaca cttatacaaa
     3781 aagagaaatt ttgtaaatat agattatacc aacatttgtt aacttatgaa aagataatca
     3841 aaatttttat gagcttttta tataaaaaat agaatgttta tatacaaaaa tattaaagat
     3901 attatagtaa gttttgta
//
LOCUS       DAMKOJ010000166         3878 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000166 DAMKOJ010000000
VERSION     DAMKOJ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.175"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(94..912)
                     /locus_tag="PC592_003515"
     CDS             complement(94..912)
                     /locus_tag="PC592_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4057438.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IESTIKRIGGNDIMKNYDVTIKNFASKYMMTLRMVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPRHSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGTWISDNDYDVDGPMFNIYHVSPGNDNNPDNWVTEVCFPVKKK"
     gene            1080..1661
                     /locus_tag="PC592_003516"
     CDS             1080..1661
                     /locus_tag="PC592_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4057439.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCIANGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEGVDVR"
     gene            1658..1852
                     /locus_tag="PC592_003517"
     CDS             1658..1852
                     /locus_tag="PC592_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057440.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(2016..3758)
                     /locus_tag="PC592_003518"
     CDS             complement(2016..3758)
                     /locus_tag="PC592_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HDF4057441.1"
                     /translation="MVKSKKKIFVSLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSEEFYSNEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLSKSTVSIDGIEIDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDICEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLDDINKLFFDLEEEYGVSNNILKEKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQGDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
BASE COUNT         1371 a          515 c          511 g         1481 t
ORIGIN      
        1 atatcctaat taaattgtag gtatttatac ataacactaa aagtaatttg tctaacaaat
       61 taaaatatta tccaattaat atataagata aaattacttc tttttaactg ggaagcatac
      121 ctctgttacc caattatcag gattattatc attaccagga cttacatgat aaatattaaa
      181 cataggacca tccacatcgt agtcattatc tgatatccaa gtaccaatag cttcacaagc
      241 atctgcaact tgattgaaat ttccattaac aattgcagtt gcagcagtca cacttggaac
      301 agtcttaaat ttaacatgct cagtatcttt atactttcca gatacagcaa cttgtacttc
      361 aacatctaca taatcttctt tatatccagt atcataaaag actgccttag aatgtcttgg
      421 tggttcaatt tgaacattct ggtcttttgt ctctaaaaat gcttgatgcc ataacattcc
      481 ttcgtcttga taagttggta taaccattct aagtgtcatc atatattttg atgcaaaatt
      541 ctttatagtt acatcataat ttttcataat atcatttcct ccaattcttt taatagtact
      601 ttctattttt aatagttttt tctgtgtatc ttctaattgt tcttttactt gagaatggtg
      661 gatatttaga tattttataa gactttcttt atcgttatat tctgtcaaaa tttcttttat
      721 agaatacaag ccaaagccca tatcttttag tgcatggatt ctgtttgttg tagaaagttg
      781 gtctgcgcta tagtatctat atccattagt tttattcgta tgagaaggag ttaaaagccc
      841 tatttcgtca taatgacgta acatacgaat actaatttta cttagttttg aaaaatcgcc
      901 tatcttaaac atgtttttgt ctcctttata aaggtacttt tagcttaata ttaatataaa
      961 ccatatcata atgttagagt caactaaaat tataattaaa ttatattgac atatgatgaa
     1021 aaaaatatta tactgaacat gttcagaact aaaaatgtta attgttttgg aggtccatta
     1081 tgaaaagtaa tgataaagat gctagagaac gtataattga agttacattg aatcttttaa
     1141 atgaagtaga tgatattgaa gagattacag ttagaaaaat tgctgagcgt gcaaatgttg
     1201 gagttggttt aataaattat cattttaaaa caaaggataa tttgttgagt actgccatag
     1261 gagatgtgat gtcaaatata atagcagagc tatatgacga tagtgtatat actctaagac
     1321 ctattgaaga tttgaaaaat ttattaaaaa aattgtgtga tactggatta cattatgaaa
     1381 aagtgcttcc ttttgtgttg aatcaatgta tagccaatgg agatatgcaa gcagaacttg
     1441 atattgtccc tatgcttcgt aaaatttttg gaaataaaaa agatgaaatg agtctaagaa
     1501 ttattgccct gcaaattatt ttaccaatac agatttctgc tttatctaca gaatcatttc
     1561 agttatacag tggtataaat ataaagaata aatatgagcg agataaattt attgatattt
     1621 taatagaaaa tattattgga gagggtgttg atgtaagatg aaaattataa ctattggttc
     1681 aagtcttatc actgttttac tttttctttc aactatggtt tgtgggttct ggattaagaa
     1741 taataaggta acagatgcaa gttctattaa gttccatatg aatagtgcta tttttacagg
     1801 gatattttta ttgatttcca caatcctttt aattatatat ataaaaaaat aataatatta
     1861 ttaatagata aagtatcaga aattataaag acaagagtct taaaaatttc tgatacttta
     1921 ccatataatt ttattaaaca ttaattgtgt gtgaaaaaat atcacttatt tcaatctaat
     1981 gctaaatctt aagagtaagc ataaagtatt aaaaattaag aagcattttt tagttcaagt
     2041 ggattatcta taccaaaata atcatataaa gtagagctta tttcctctaa atttccatct
     2101 tggaaaggta attgtaaatt caccttttct accacatcct taaatccagc atcagtattt
     2161 tgatttaaaa aatccatata tacatcaaca gcttttctgt aatcaccttg tgataattgc
     2221 catatctgaa gtgatacatc agatgcaaga ccataactca agtaataaaa aggaacttgg
     2281 aagttatgag atacaagtat ccaaaaagga gcattttttt ctttaagtat attattggaa
     2341 actccatatt cttcttccaa atcaaaaaac aatttattga tatcatctag actcatatat
     2401 ggattcttat atataatttc ttgaaattca tcataaagac aagcatcaat aatagtgttt
     2461 aaaacaatcg ataagtgttc tttttttata gcttcagatt gtttcccaaa aaaatcatca
     2521 aaatatttgt aaaatagaat ttctaaagat gttgaatgaa cttcacatat atctatactt
     2581 ggttgcatct tattatttaa gttaatactg ttgtagtaat tataaaaatg accaaattca
     2641 tgggcaaaac tagtaacacc taaaaaagaa ttatcccatg tattaaataa gaaaggagct
     2701 ttatacttat ttatataagt ggtatatcct ccaggtgatt tgttctttcc agaagaataa
     2761 tcgtacaagt catatttttt catatagtca aagctctctt ttagttttgg agatatatct
     2821 tcaagcacct tatcaaactt tctaaatgag cgatttttat atactttaat ataaatagaa
     2881 gaatcagaag gtttagatga aatctctcta tataatggaa ctatgtaatc ttttacatct
     2941 tgtctaaatt ttttagcttc ctcttgagaa taatctttgt ttaggttcat ataggcataa
     3001 tctatataat ttttaaaacc ttgcttactt gctatttcag ttcttgtctg tataagttct
     3061 aagaatatgt taccaaatat agggttgtat ttttttaagt aatctgaata aattttaaca
     3121 tattcttcag ggctaagatt tggtcttgac aaggcttctt caaagtctat ttctatacca
     3181 tctattgata ctgtagattt agataacaag tcttcatatt ttacaactag gtcttgttct
     3241 ttcttaagta aaccttcaac ttctttagaa ttaagttttc caatgttctt tagataatta
     3301 aatgtatctt ttccaagttc tttttctaat tctttagaga atttagaagt tacaaatcta
     3361 tcttgaaagt ctttgtatga catgtcaaca tctactgatt tactcataag atacttgtat
     3421 tcattagagt aaaattcttc tgatgaatct atgttatttc taatttttgc tatagtaagt
     3481 gtactgtaaa aatcttgata aattttatca acttcattaa ataaatttaa ttgttcttta
     3541 gctgttttag ctgttaaaag tttgtcgtta catttgttaa tgttttcgca aattgactgt
     3601 atattaggac gcttatattc cattttttca aaaggaatag ttcctctaac agaatctttt
     3661 tttgtatcat tagtataatt tcttatgtat gatgcaaata taataaaaac tgcaattaaa
     3721 attagagaaa caaatatttt cttcttggat ttaaccataa aaatcctcca atcatggata
     3781 tagttattaa ttattttact atattaaata taaaaaatgc atgttaagaa aatttaacat
     3841 aaggatatgg ataagattat aaataatata aaaaattt
//
LOCUS       DAMKOJ010000167         3795 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000167 DAMKOJ010000000
VERSION     DAMKOJ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.176"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            27..695
                     /locus_tag="PC592_003519"
     CDS             27..695
                     /locus_tag="PC592_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057442.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     KGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYKDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGILYKNDGNKQAGIWEDDEQCKSLDFKDLSNNEISKVSQNRLNNN
                     KLRV"
     gene            854..1360
                     /locus_tag="PC592_003520"
     CDS             854..1360
                     /locus_tag="PC592_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF4057443.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLNLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1488..2504
                     /locus_tag="PC592_003521"
     CDS             1488..2504
                     /locus_tag="PC592_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF4057444.1"
                     /translation="MGYYNDNDNNKIRRKKISNSKDSNKKSKHSYTSANKKNKSSKTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPDDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGGSTIDMQVSKNLLTS
                     DDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVNE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQLIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2860..3564
                     /locus_tag="PC592_003522"
     CDS             2860..3564
                     /locus_tag="PC592_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HDF4057445.1"
                     /translation="MKKFVIEDTFWNLFPNAKIGVIICNDIDNSIKDEDYKKIILQGE
                     EEALKYLEDSEFSKNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENLFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALSELAKIVQEKLGGK
                     CKISILDIDNKEVSVD"
BASE COUNT         1617 a          317 c          668 g         1193 t
ORIGIN      
        1 ataaaatttt taaagggtga ttttttatgg aaaatataac tagttatttt acaacaatac
       61 tatgtgtatt tatatgttta tcatctgtat ttatatttac tcaactagct agagtattta
      121 ttaataagaa gaagattaat caaaaaatta aatcaagaaa aggatttagg tatgatagag
      181 attttattga agctagaaga gaagaaatac atataaagga taacaataat aataaaaata
      241 agagtaacaa taagaaatta aagggagaaa aagtatttaa atatgataat ggagatttat
      301 ataaaggtga gtttgttgat gggaagaaaa atggatttgg aatatatatt ttttcaagta
      361 aggaaaagta tgaagggtta tggaaagatg acaagatgca tggaatagga aaatatactt
      421 ataaagatgg ttcaatatat acaggtgaat ttaaatacgg attaaaaaat ggtttgggga
      481 aattaacata tcccaataat gatatttata agggatattt tttagataat aagaaaaatg
      541 gtaagggtat attatataaa aatgatggaa ataaacaagc aggaatatgg gaagatgatg
      601 aacaatgtaa aagtttagat tttaaagatt taagtaataa tgaaataagt aaggtttctc
      661 aaaacagatt aaataacaat aaattaagag tttagttatt ctaataaaaa aatctttatt
      721 tatgatggaa tatagaatat gtttatgctg taatttgtaa aatcttccta tatcatataa
      781 aattaagtat tgattagtct attacataaa tatagaatat aaatatatcc atttgataat
      841 aaggagaaga gatatgaaag agtatgtagt tgtggattta gaaactacag gattagatcc
      901 atataaaggt tgtgaaataa tagaaatagg aataacagaa ataaaaaatg aacaaattgt
      961 aaaaaactat tcaaggttga taaaacctaa ggggataatt tcttcattta taacagaatt
     1021 gacacatata agtaatgaaa tggtagaaaa tgaagaacct ctagaattag ttttacctag
     1081 atttagaaag tacataggtg atagaactat aattgcacac aatgcgaaat ttgatttaaa
     1141 atttttaaat tactatctta gaatgttaaa tttagaacca ataaacaatt atatatgtac
     1201 agtagaatta ttaaaaaaat gtaaaagtta taaaggaaaa aataagaaac ttgaaacagc
     1261 ttgtgcttat tacaacatag agaatataaa tgctcataga gctgatagtg atactttagc
     1321 aactgcaaaa ctatttttga aaataaaaga tgaatattaa tcataaatat agagaaaatt
     1381 agtgaaaata tcctttataa aattgaccct taaacttaca attttgttct ttgatttatt
     1441 ttgtagaaca atgtataatg taccttatat gaagaaggga gactaaaatg ggttattaca
     1501 atgataatga taataataaa ataagacgta aaaaaattag taacagcaaa gatagtaata
     1561 aaaaatctaa acattcttat acttcggcaa ataaaaaaaa taaaagttct aagacaagtt
     1621 ctagtaaaag aatgagcgaa aaagtagatt cacagaatct tataaaaaga gatagagata
     1681 gttttacaag agataatgta agacctttaa atacagatta taatcaaaga gaaagaagaa
     1741 gagtcgagta taaacaaaga gagaaaaaac taaaaagtaa aaaaagaaaa aaacaaaaaa
     1801 ggattagaat agttagggca ttgttatcta ttatgttagt tgcactaatt atattttcag
     1861 tggcaggtgc aatatttaca gtttcagcta taaaagggtc accagaagtc actaaaaagt
     1921 taattaggtc taaatatata agtagtgagg ttgtaagtat aaaacaaatg ccagatgatt
     1981 taaaacatgc aatagtttcc atagaagatg agagatttta taagcataaa ggagtagatg
     2041 ttatttcttt agttaggtca gtactaaaca atgtgtttac agatacaaca caaggtggaa
     2101 gtactataga tatgcaagtt tcaaaaaatc tgcttactag tgatgataaa actatgaaac
     2161 ggaaaataag ggatatgtat aatgctaagc aaatgaataa gattatgact aaggatgaaa
     2221 ttcttgaagc ttatttaaat aatatgtacc taggtaaaaa tgcatatgga gctgcaaagg
     2281 gagctgaagt ctactttggt aaaaaagtta atgaattaaa tttagctgag tgtgctatgt
     2341 tagctggtat gacaaataat cctgcaaggt atattgacca tggagaggct aagaagagac
     2401 aattgattgt attgtataag atgcatcagc ttggttatat aactgataag gagtatagaa
     2461 tagcaaaagc tgatgacact ccatttaaat ctgaaattga ttaaaattgt aaagatgtgg
     2521 tatttagaac agttcaaaca aatgaaaatg taataaaaaa ggtgatttgc cacccatctg
     2581 tcaccataat tataatctta tggcaaattg ttttaattca caaattagat aatagaatat
     2641 tgttttaagt gctatagtat gctaaaattt aaaattgtat tttataaatt aaaaaaagtt
     2701 ataacttagt tttctagggt tccgcatttt ataatggtca ggtccaagag aaaacgcaca
     2761 attattgtgt acacggaagg ataaaagcct gggagatatt taataatatt tctataggct
     2821 tttttatttt tatatatttt aaatttaagg aggtttttaa tgaaaaaatt tgttattgag
     2881 gatacatttt ggaatctatt tcctaatgcg aaaattggag ttattatttg taatgatata
     2941 gataactcta taaaagatga agactataag aaaatcattt tgcagggaga agaagaagca
     3001 ttaaaatact tggaggattc agaatttagc aaaaaccaag tgattaaagt atggagagaa
     3061 gcatttaaaa aatttaaaac gaaaaaagga gcaaggtctt ctattgaggc attattaaaa
     3121 agagttcata atggaaataa tataggaact attaaccctt tagtggatat ctacaatttt
     3181 atctcattaa aatatgcatt accttgtgga ggggaggata tagataaatt tataggagat
     3241 attaggctaa ctagagcaat tggtaatgag gagtttatcc cactagggac agatgaaaat
     3301 ttatttccat atgaaggaga aataatctat aaagatgatg gtggagcaat ttgtagatgt
     3361 tggaattggc gtgaagcagt gagaacaatg cttactgaag atactaataa cgccttttta
     3421 tgtattgaat tagtagatga aagtagattt aaagaatttg aaaatgcttt aagtgaatta
     3481 gctaaaatag ttcaagaaaa attgggtggg aagtgtaaaa tctcaatttt agatattgat
     3541 aataaagaag tatcagtaga ttaatctgga ggtgctgttg taatgggcta ttctagttat
     3601 aaagatactt atatttaggg taagaaggtc tattttagat gcaacgatta tcaaaggata
     3661 tgatatagaa aataaaaatg tggaatataa aaagccttta aaataagaaa aaattgtatt
     3721 ttaaaggctt ttattatact attttttatt tgcacaatta acaataaaaa tatattgtta
     3781 attataatat tttta
//
LOCUS       DAMKOJ010000168         3777 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.177, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000168 DAMKOJ010000000
VERSION     DAMKOJ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3777
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.177"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            286..1866
                     /locus_tag="PC592_003523"
     CDS             286..1866
                     /locus_tag="PC592_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDF4057446.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTCGKEVNVFLVGNIEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYETSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRREKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     SKLLSSSDAIGFGPGMGNNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNVVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDELSKTMYTVN
                     ATDLISNISLTMKELLDI"
     gene            2036..2482
                     /locus_tag="PC592_003524"
     CDS             2036..2482
                     /locus_tag="PC592_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDF4057447.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVVLIFLSSFIESI
                     FLQILIFAVISIAMLVIATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVNATTSVTNQ"
     gene            2503..3546
                     /locus_tag="PC592_003525"
     CDS             2503..3546
                     /locus_tag="PC592_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDF4057448.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHLLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQIATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEIFD
                     VKEALGDNESLKK"
BASE COUNT         1531 a          336 c          708 g         1202 t
ORIGIN      
        1 tttttataaa aatgaaaaat ataaataagt cataaaagat tatgaaaata aagaaatatt
       61 tagataatta gtgtaaatag gttttaaatc aacataatag cttaatttat atggtataat
      121 aaattaaata attactttaa ttcaaaattt tttgttattt taaattattt caaaaatatt
      181 agttttagtg attttattta tgatatttat gtgcttagaa agatttcaat agatattttt
      241 ttatgaatat ttaagaagtc tttaacttta taggagtgat aatttatgct aataggtaca
      301 tctaagttaa gtagaaatgt tgatactgca tgtgtagaag aagtaggtat tccaatgatt
      361 gtattgatgg aaaatgcagt tatatctgca atgaaaaata tggatataga catgtataat
      421 agttatacag ttgtatgtgg tgttggaaat aatggaggag atggtcttgg aatagcaaga
      481 catctaaata catgtggaaa agaagtaaac gtatttttag taggtaatat tgaaaaacta
      541 agtgaatgtt ctaaaataaa ttacaatgta cttttaaata tgggaattaa tattataaat
      601 attaataaaa atgatttaag tgaaaaaaat tatggagatg aaaatgaagt agataaaatt
      661 attaaagttg agaaacaaaa tattataaaa aataaaaatt taacaatttt taaagataga
      721 gtatctaaaa gtgatgttgt agtagatgct atatttggga ctggactaaa acgtgatata
      781 actggtattt ttaaagaagt tattgacata gtaaacgata atagcaaaaa tacatattct
      841 atagatattc cttcaggtat agatagcgat aatggaaatg tattaggaac ttgtattaga
      901 gcaaacaaaa cgattagctt tgagttttat aaaagaggtt ttctaaacta tgagactagc
      961 gcacttatag gtgatgtagt tgtagaaaag ataggtgttc cagattttat tacaagaaaa
     1021 taccatgatg aagagttcat aactgataag acttttgtaa aaaataatat tagaagaaga
     1081 gagaagcatg gttttaaaag tgattttgga aaagtatcta tagttgcagg ttcaaaagga
     1141 ttttatggtg caagtttcat agcaactgaa tctgctgtta agagtggaag tggacttgta
     1201 actttaatta gtagtgaaga tgtgcaagaa aaggtatcta ttagacttac agaagcaatg
     1261 actttaaatt ttgaagagga aagattaagt aaattactta gttctagtga tgcaattggt
     1321 tttggtccag gaatgggaaa caatagtcaa acatttgata aattacttaa gatagtcgaa
     1381 aattctaatt gcccgatagt attagatgct gatggattga acgttatgaa ggacagatgt
     1441 tataagtttt tagaatggaa aaatagattt gtaattacac ctcatttggg agaaatggcc
     1501 aggttgacag gagattcaat tgggtatata agagaacata gagtagatgt tgcaaaagaa
     1561 tttgctcaaa aatataatgt ggttgtgctt ttaaaaggtt atcaaactgt cataacagat
     1621 ggtaaaaaaa catatataaa tcctacagga aatagctgta tggcaactgg tggaatgggg
     1681 gattgtttgc ttggaatgat tacttcattt ataggtcaag gtatggatat attggaagct
     1741 acagttagtg gagcatatat acatggctat ataggagatg aattgagtaa aacaatgtat
     1801 acagtaaatg ctacggattt aataagtaac atttcattaa caatgaaaga gttgttggat
     1861 atataattaa tgatatttga tactactttg taacaacttt aacaaagtat gttgatataa
     1921 tactattaat taatttattt tattgttttg taatttaaat ttatattcaa aaacattgta
     1981 taaacatata atttatatag ggttttataa ttcatatgaa aagagggtag atagtatgaa
     2041 gttaatatgg ttgatagtag cagtcttatt tggaatagca gaaatgttga caccaagctt
     2101 aacattgata tggtttagtg taggagctgt agtacttata tttttaagta gttttataga
     2161 aagtattttc ttacaaattt taatatttgc agtaatttct atagcaatgt tggtcatagc
     2221 tactaaaaaa atagtaaaaa aagataaagg ctacaaatct aacactaatt tacaagcaat
     2281 gatgtctaaa aaaggtattg ttacagaaga gatttctcca aataatacag gtctagttgt
     2341 agttgaacat gaaacatgga cggctatttc tatagatggt gaaaagatag aaaaaggttc
     2401 tacagtagaa gtattaaaaa ttgaaggggt aaaactagtt gttaaaaaag taaacgctac
     2461 aactagtgtg acaaatcaat agaataaagg aggatttata gtatgggtac taaaattgtt
     2521 ttaagtattg tattaatagt agtagtcgta gcaataagtt taacctgtat aagagttata
     2581 aaacaatcta aagtaggtat aataatgaga cttggtaagt ttcaaaaagt ggctgaaaca
     2641 ggtgtacatt tattaatacc atttttagat aaaatggcat atgtaattga ccttagagaa
     2701 attgtaatag attttccacc tcaaccagtt ataactaaag ataatgtaac tatgcagatt
     2761 gatacagttg tatattataa agttacagac ccagttagat atgtgtttga gatagctaat
     2821 ccaatagctg ctattgaaaa tttaacagct acaacactaa gaaatataat tggtgaactt
     2881 gatttagatg aaacattaac atcaagagat ataataaatg taaaaatgag aactatcctt
     2941 gatgaagcaa cagataaatg gggtataaaa gtaaatagag tagagttaaa aaatataatg
     3001 cctcctcagg atattcaagt tgcgatggaa aaacaaatga gagcagaaag agaaagaaga
     3061 gaggcaatac ttcaagcaga aggtaataag tcagctgcaa tacttcaagc agaaggtgaa
     3121 aaacaatctg ctatattaac agcagaagct aaaaaagaag ctatggtacg tgtagcagaa
     3181 ggtgaaaaag agtctgctat attagtggca gaaggtgagg ctgaagctat aagacagaca
     3241 gctattgcta aggcacaagg tgaagctgaa atgataaaaa gaactcagat agcaacagca
     3301 gaaggtttaa aactagtctt ttcagcaatg aaagaggctg atatagataa taatattcta
     3361 gcattaaaat ctatggaagc tcttgaaaaa atggctgaag gtaagtcaac aaaactggtt
     3421 ttaccttcag aagcagttaa tttcttagga acattcaaag gaataaaaga agttatgagt
     3481 gatgataaca aagaaatatt tgacgtaaaa gaagctttag gtgataatga atcattaaaa
     3541 aaataaaaga gttttgttat cataggaagg atatggaaat taaaggtcga attaattaaa
     3601 tatagtaaaa aaatgcacgt tgaaaagaag aggacttata aatttttaag tcttcttctt
     3661 tgtttttatt ataaagatga aattataaag atgaattaac agaattttta tacaatttat
     3721 tctttactaa tgtaaaaagt gttatataat attatataaa acatatagca aataagc
//
LOCUS       DAMKOJ010000169         3405 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000169 DAMKOJ010000000
VERSION     DAMKOJ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.178"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            16..1005
                     /locus_tag="PC592_003526"
     CDS             16..1005
                     /locus_tag="PC592_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF4057449.1"
                     /translation="MELKDRSLVNNQYKGKIKSANLSVDYEISQVMKDIDKLGLNTVN
                     VPIIINVESINSDIMSIDNNSKEKAIKLIKKLNKKGISTILEAYPWIENGKLYETDWN
                     PINKKRFFYTWQNTILNEIIIDVANPLDVNVLNIGSNFVHLEGYQQNWSEIIDFVQSK
                     FDGLVTYRTNWWYTKKDDLNSKLSYEQKLNNNFFDKLDFISIAAYFELSNKRINTVDE
                     LISALYSSTVNNRRQNIKKEIYNLYKAHRKPIFFGELGFSNREYASSQPWNHATSKVV
                     NGEEQARCFEAYKKVFENEEWINGFSVFCIGKIDDEKNFYPSKESIKVIKSWY"
     gene            1062..2186
                     /gene="wecB"
                     /locus_tag="PC592_003527"
     CDS             1062..2186
                     /gene="wecB"
                     /locus_tag="PC592_003527"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDF4057450.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRANIKSIVCVTAQHRE
                     MLDQVIETFNINIDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIVLVHGDTTTT
                     LATSLTAFYNKIIVGHIEAGLRTYDKYSPFPEELNRQLTGVIADMHFAPTNLAKKNLL
                     SEGKPYNNIFVTGNTAIDALKMTIKENYSHPIIDDIGNDRMILLTSHRRENLGKPMKN
                     IFKAIKRIVDDFEDVQVVYPIHLNPKIRTIADEIFGKFPKKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLREKTERTEGIEANTLKLVGTNEDRIYNSVSNL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            2294..3268
                     /locus_tag="PC592_003528"
     CDS             2294..3268
                     /locus_tag="PC592_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF4057451.1"
                     /translation="MARKLIKNLGKSKSAKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLVDVIRSYNLQLIDNKVETK"
BASE COUNT         1420 a          334 c          596 g         1055 t
ORIGIN      
        1 atttactttg taagtattga gttaaaagat aggagtctag taaataatca atataaaggt
       61 aagattaaat cagccaattt atctgtagat tatgaaataa gtcaagttat gaaggatata
      121 gataaattag gattgaatac agtaaatgta cctataatta taaatgtaga gtccattaat
      181 tctgatatta tgtcaataga taataatagt aaagaaaagg caattaagct aataaaaaaa
      241 ttaaataaaa aaggtatttc aacaatatta gaggcatatc catggattga aaatggaaaa
      301 ttgtatgaaa ctgactggaa ccctataaat aaaaaaagat ttttttatac ttggcaaaat
      361 actatattaa atgaaattat aattgatgta gcaaatccac tggacgtaaa tgttttaaat
      421 attggttcta attttgtaca tttggaaggg tatcaacaaa attggagcga aataatagat
      481 tttgtacaat ccaaatttga tggtcttgta acgtacagaa ctaattggtg gtatacaaaa
      541 aaagatgatt taaatagtaa gctgtcttat gagcaaaaac tgaataataa tttttttgat
      601 aagttagatt ttatatctat agcagcatat tttgagttaa gcaataaacg tattaataca
      661 gtggatgaat taatttctgc cttgtactca tctactgtaa acaatagaag acaaaatata
      721 aaaaaagaaa tatataacct ttataaggct catagaaaac ccatattttt tggagaatta
      781 ggtttttcaa atagagaata tgcaagttct caaccgtgga atcatgctac ttcaaaagtt
      841 gtaaatggcg aagaacaagc aaggtgtttt gaggcatata agaaagtttt tgaaaatgaa
      901 gaatggataa atggtttttc tgtgttttgt ataggtaaaa tagatgacga aaaaaatttt
      961 tacccatcaa aagagagtat aaaagttatt aagtcttggt actaataatt ttgaaagttt
     1021 agaatttata gatgttaaat agatgattag gagagatata aatgaatgac atcaaggtta
     1081 tgactgtatt tggaactaga cctgaagcta tcaaagtagc acctttaata aaggaacttg
     1141 aaaaaagagc aaatataaaa agtattgtgt gtgttacagc tcaacataga gaaatgcttg
     1201 accaagttat agaaaccttt aatataaata tagattatga tttggatata atggaaaaag
     1261 gacaaagtct gaatgatata acatgtaaga ttttaaataa acttcccttg attttaaaca
     1321 aagaaaatcc aaatatagta ttagtgcatg gagacacaac cacaactctg gctacaagct
     1381 tgactgcatt ttataataaa attattgtcg gtcatataga agctggtctt agaacatatg
     1441 ataaatattc tccatttcca gaagagttaa ataggcaact tacaggtgtt attgctgata
     1501 tgcactttgc tcctactaat ttggctaaaa aaaacttgct ttctgaagga aagccctata
     1561 ataatatatt tgtaactggt aatactgcta ttgatgcttt aaagatgaca ataaaagaaa
     1621 attatagtca ccctataatt gatgatattg gcaatgatag gatgattttg ttaacctctc
     1681 acagaagaga aaatttgggt aagcctatga aaaatatatt caaagctata aagcgaatag
     1741 tagatgattt tgaagatgta caggtagtat atcccatcca tttaaatcct aaaatacgaa
     1801 ctatagctga tgagatattt gggaaatttc ctaaaaaaat tcatattatt gaacctttag
     1861 atgtagctga ctttcataac tttttaaata aatcttatat gataatgact gatagtggag
     1921 gaatacaaga agaagctccg tcattaggta agccagttct tgtgttgcgt gaaaaaacag
     1981 aaagaacaga aggaattgaa gcaaatacac ttaaattagt aggtactaat gaagatagaa
     2041 tatataattc agtgagtaat ttattaataa ataaagataa ctatgttcag atgagtaaag
     2101 catccaatcc atatggggat ggaaatgcaa gcaaatatat agttgacata ataattaaaa
     2161 aatttaattg taagtattta aattaggttt ttatgctcaa cttgaaattt atattagata
     2221 agaattaaaa cattaacgaa ttgatataag atttattata ctatgaggga tacaattttt
     2281 aagggggaat aatatggcta gaaaattaat aaaaaattta ggtaaaagta aaagtgcaaa
     2341 gagagtgaag cttttattta agaagatttt tattactgta ttcatagtag caagtatagt
     2401 tgctattttt aatataacga aatattttga ggaattatac aaagtaagag atttaaaaag
     2461 tactaaaatt gaatactata tggatgtagc tgatgaagca ggggatggaa aggttcagtt
     2521 aagttggaag gccttacttg ctatagacat ggtaatacat gatgaagatt taagtaatat
     2581 aaaaaagaaa gacacattgg atataggaga aaaatttata gtagaagata aaaatgataa
     2641 aggcgaaaag gtgtataagg taaaaaagtt taataaggta ttaagcgaat tgaaatttga
     2701 ctcttctcaa aaaagtagag caagaaaata catgaaggat ttggaataca cataccttgg
     2761 aaataaacaa ttagatagta gtgatgaaaa aattaaattt ataaagaaat tagaagattc
     2821 agctataaga gaatatattg attatggaat attgccttct ataacaattg gacaagctat
     2881 attagaatct ggctggggaa attctaaact tacaaaacag agtaataatt tatttggtat
     2941 aaaagcagat aaagcatgga aaggaaaaag tgtagaaatt tcaacttcag agcattataa
     3001 tgaaaaaatt gtagctagtt ttaggtctta taattcatta caagattctg tcaaagacca
     3061 cagtttattt ttaattaata ataaaagata tagaaaacat ggattgtttg aggcaaaaga
     3121 ttatattagt caagctcaag cattagaaaa tgcagggtat agtacagcag aagataaaaa
     3181 aggaaatcgt atatatgcag agctattagt agatgttatt aggagttata atttgcaact
     3241 gatagacaac aaagttgaga caaaataatt gttaactcta tatgaagaga tggcaagatg
     3301 agattatttt ctacaaaaga atagaaaaat tgtaaaaaaa actaaaaaaa tgtattgact
     3361 tgttatttaa aaggtgatat tattattact gtactcgaaa gagaa
//
LOCUS       DAMKOJ010000170         3403 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000170 DAMKOJ010000000
VERSION     DAMKOJ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3403
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.179"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..2059)
                     /locus_tag="PC592_003529"
     CDS             complement(<1..2059)
                     /locus_tag="PC592_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDF4057452.1"
                     /translation="MKKFIISIISLVLFFSNISLIDKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEDVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKVKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKMENSINEYPYPYAEIENNLKLDTTIVVPDNMTRGESTAVFNLASEFGKIIKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSTEEQTLLSSNCLIKQVDSPYNKN
                     KKMMVVIGSNEENLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIVLNLRYSDNLHFEKSLVTVSIN
                     DVLVGSKKLDRQHSNNDKLELKIPKDIDNKNYYQVKLVFNLNIKNSNCVTRESNNPWA
                     YVSNSSYLALSTKENEALSFESYPYPFVRNDEFNDLTVIMPDYSDSQAMTWMSKLGVT
                     LGANINSHNGNMNVIRGKEFSDKYKDTNIIVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FLSNDKLSFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKNSSWNMSINKTTKVFLMISFITIIVVIIL
                     SMLY"
     gene            complement(2082..3338)
                     /locus_tag="PC592_003530"
     CDS             complement(2082..3338)
                     /locus_tag="PC592_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4057453.1"
                     /translation="MRDLNVSECLFVFSLCSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMVSILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILED
                     IKNKYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDRNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIKNIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
BASE COUNT         1141 a          529 c          326 g         1407 t
ORIGIN      
        1 tatataacat tgataatatt atgactacaa ttatagtaat aaaagaaatc attaaaaata
       61 ctttggttgt cttatttata ctcatattcc aacttgaatt ttttacttct ttcttaggtt
      121 ttaaattata agctaaatct tctacctctc catattcatc aattatcaat gtatctcctt
      181 ttaaatcatt aactttactt ttattcaaca aataatccat tcctaaatat aagttttttt
      241 cattcattga actaattacc atgatatttt tttgattatt atatggtgat tttattaatt
      301 gaatggtaga aatatttttc ccataatcat caataaagct taacttatca tttgataaaa
      361 aattggagta atttttatcg aattttatat ttaaattatt atttaacatc tttataacag
      421 aattattatg cggtactcca aaaactataa tattggtgtc cttatacttg tcgctaaact
      481 cttttcctct aattacattc atatttccat tatgtgaatt tatatttgca cccaaagtaa
      541 cacctagttt agacatccat gtcatggctt gtgaatctga ataatctggc attatcacag
      601 ttaaatcatt aaactcatca tttctaacaa atggatacgg ataactttca aaagataaag
      661 cttcattttc ttttgtagat aacgccaaat aagaactatt tgatacatat gcccaaggat
      721 tattactctc tctagtaaca caattcgaat tttttatatt caaattaaat accaatttga
      781 cttgataata atttttatta tctatatctt taggtatttt taattctaac ttatcattat
      841 tagaatgttg cctatccaat tttttacttc ccacaagaac atcatttata gacactgtaa
      901 ctaaagattt ttcaaaatgt aaattgtcag agtatcttaa attcaagaca atctttgaac
      961 catcatctag taccttacct gtcggtattt tgacatcaaa caaagcttgt tgattaaatg
     1021 ctccttccaa caaaaagtca gaatatccta agtcttttaa agttaaatga cctaagttta
     1081 gtttttgttc tctattgatt tttatattag tctctttgtt tacaagtact gatgatgata
     1141 aaacttgatt agaaagtcta ttttctatta ataaatttga tgcctttatt aaattttctt
     1201 cattactacc aattacaacc atcattttct tattcttatt gtatggtgaa tctacttgct
     1261 tgattagaca gttcgaagat aatagtgttt gttcctctgt acttaaaatg tccaagattt
     1321 cttctgctgt attttcaggt ttaccaatat atataatatt atcatctgac caatttttca
     1381 tttctgaata taatttaaca tctaacttta aatcatcatt ttttattatt tttccaaatt
     1441 ctgatgccaa attaaataca gctgtagact ctcctctagt catattatct ggtactacta
     1501 ttgttgtatc taatttaaga ttattttcaa tttctgcata tggatacgga tattcattta
     1561 ttgaattttc catctttttt tgtttatatc taattgatat atatgattct ttgtgaataa
     1621 ccatccagtt cccagtattg gaatcatctt ggcaaatttt atcagatatt gttttatatg
     1681 tttttacctt tatttcgtta tagccttgaa ttatataatc ttttggaact aatacttcta
     1741 gtgtattttt ataatttgtc ttagcattta atttaataga ttttattggt acattattta
     1801 tcaaaacagt taaacttgaa acatctccat ttaatatttg gctcttacta aaattaagat
     1861 gtaataaaac gtcttcaata tcccaatttt tatttacttc aaaaaaagta ctattacttc
     1921 ctataacacc atcaatagtt atatctcttt caaacttata atttttaact ttagtctcgt
     1981 cagcatttac tttgtctata agtgatatat ttgaaaaaaa caatactaaa gatataattg
     2041 atataataaa ttttttcatg ttaattcctc ctgtacatga attaaaatct ttctgtttta
     2101 taccatttaa cttctctttt aaaaattata tcttttagat actctatcat tccttttata
     2161 gcgacaaaca accatagttg agagtatgta aaatacatta ttgcaactat gaatatattt
     2221 ttaattgttg cttcaccttt ttctatagta aggcttatac tcacttctat aataaataaa
     2281 agataagata gtatccatat tagaaaaaag ttaattggaa tagaaatttc tactagctta
     2341 gatatactta aaacaaataa aatatcggat ataatgacag atgttaaaaa tagaaaatat
     2401 acagaaaaaa agtaagctat atcaaataca atcttatttc ttccttgctt aaatatattt
     2461 tttatgtatt tcattaatac atatatattc ccttttgccc atctagtacg ttgttttatc
     2521 cataccttaa cagtttctgg ctcttgttcc catgttatag attgtggtac aagctttatc
     2581 ttgtatccca atttatatat cctaaaactt atttctgtat cttctgcaat tgctttacta
     2641 tcccatcctc caatttcctc tatgatactt ctcctcaata taaagttagt tcctggtatt
     2701 gtacatagat taaaaagttg ccatctacca gcttgtgaca tccattgaaa acttaatgtt
     2761 tctatgttta taaatttggt taataggttt ttatttttat ttcgagtcct aaatttccca
     2821 ataacagcac ctaattcatc attcattact atagtttgta ctaaatatct aagtgcattt
     2881 ctatctggtg tgttatctgc atcataaaca gctataaaat ctccttttga aatcgtatat
     2941 ccaatattta atgcattaga ttttcctttt ccacctgtta aactatctgt atttattatg
     3001 gtgaaattat agttattgta cttattcttt atatcttcta aaatttcttt actattatca
     3061 gaagaattgt catttataac aataagttcc attttactct taggataatt gagtaataat
     3121 aaagattcca cagttctacc tatcacttta gcttcattat gagcaggaac aagtattgat
     3181 accataggat attcatcaat ttcttttatt tctttatcaa agtttttaaa gtaaaatata
     3241 tatccaccca tagctaaaat aatatttata agcaataaag accatatact acacagacta
     3301 aatacaaaca gacactctga tacatttaaa tctctcataa atttctccta aaatatttta
     3361 aaatattaat tctaatataa aatcatttat tttaaaaatt tct
//
LOCUS       DAMKOJ010000171         3391 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000171 DAMKOJ010000000
VERSION     DAMKOJ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.180"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            237..461
                     /locus_tag="PC592_003531"
     CDS             237..461
                     /locus_tag="PC592_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057454.1"
                     /translation="MEYSKGFKVIYSLVEYSKRFKAIYSVMEYSKGFKAIYDVMEYSK
                     GFKAIYDVVKYIQGDLNQSIVLLNIQRDLK"
     gene            634..903
                     /locus_tag="PC592_003532"
     CDS             634..903
                     /locus_tag="PC592_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF4057455.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNTGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(1096..1341)
                     /locus_tag="PC592_003533"
     CDS             complement(1096..1341)
                     /locus_tag="PC592_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HDF4057456.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFVSTENPEPEKLKWWYWKD"
     gene            1759..1944
                     /locus_tag="PC592_003534"
     CDS             1759..1944
                     /locus_tag="PC592_003534"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057457.1"
                     /translation="MFSKKNEGNEFSNEGKGISKKIIKFFKSTKGIALLAFIFGVFFG
                     NISSPACSEDHEEVISN"
     gene            1996..2277
                     /locus_tag="PC592_003535"
     CDS             1996..2277
                     /locus_tag="PC592_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF4057458.1"
                     /translation="MSDAEPWFKMKDDEKKAIEAENQRKAEEAKKAEEEKKGYDTGIT
                     YDQLARTSDDYKYKKVKFEGKVIQVIEDGDEVQIRFAVSGNYDKVVLCS"
     gene            complement(2785..>3391)
                     /locus_tag="PC592_003536"
     CDS             complement(2785..>3391)
                     /locus_tag="PC592_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HDF4057459.1"
                     /translation="KHFYFNTDGIMQIGVFKGPDGFEYFAPANTDANNIEGQAIRYQN
                     RFLYLHDNIYYFGNNSKAATGWVTIDGRRYYFEPNTAIGANGYKIIDNKNFYFRNGLP
                     QIGVFKGPNGFEYFAPANTDANNIDGQAIRYQNRFLHLLGNIYYFGNNSKAVTGWQTI
                     NGNMYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
BASE COUNT         1229 a          407 c          491 g         1264 t
ORIGIN      
        1 tataactaaa aaatcattaa atatattaaa taaatattta actttaatga cctatattta
       61 attatggcta taacatagaa ttatcaaata tattgaataa atatttgacc cttgaaatgt
      121 gtaattaaat taagtttggt tatttgatgg aatgcaaatt tgatataaaa actccattta
      181 aagtgccaga taaaaacttt atggttatat aaaagctaaa agtaatttat agtgttatgg
      241 aatattcaaa gggatttaaa gtaatctata gtcttgtgga atattcaaag agatttaaag
      301 caatctatag tgttatggaa tattcaaagg gatttaaagc aatctatgat gttatggaat
      361 attcaaaggg atttaaagca atctatgatg ttgtgaaata tattcaaggg gatttaaatc
      421 aatctatagt tttactaaat attcaaaggg atttgaagta atttattgtg ttttgaaata
      481 ttcaaaaata tttttggaat agtttttata aatttaccag tactaataat tttatgttta
      541 acgtttagat gacttaaaat caattatttg cacttttgta gtcatctaaa gttattttat
      601 aatattttta aataatggaa aggatgtttg aatatgtttg aatcaagatg tggtgtctgt
      661 tgtgacagtt gtacaaaaaa agaacaagta aattgtactg gttgcccaac tatggaaaaa
      721 ccattttggg gtggagaatg taaggttaaa acttgctgtg aaagtaagga acttaatcat
      781 tgtggtgaat gtgatacttt cccttgtgat atgcttttaa atacgggaaa agaccaaggt
      841 tttgacccta tggtaaatat tgagcaatgc agaaaatggc ttgaagaaac agtttctaat
      901 taattgtttt agaatgtttt gttaagcaat ttatttaata ctttgttaga tagtatgttt
      961 agtcatttgt tgattggtat atttagccat acaaatagat ttacataaaa tttacgacta
     1021 aaaaagagtt gagtattagt ttttattatt aaaacagata ttcaactctt ttttatatct
     1081 aacttttttg attttttaat ctttccaata ccaccacttt aatttttctg gttctggatt
     1141 ttcagttgat acaaaatata ctgcacatct gtatacatat aactgacatc tgtctatgtg
     1201 ttgtccacgc attaaacatt ccttttcata catttgtgct gggtttgcat ctttaagtga
     1261 tttaatagtt gtatatccta acatgattaa agatttttct gttgctttcc ctacccctgg
     1321 aattttttgt agttctccca tacttcacct tctttctggt atattatttt tgtattatac
     1381 ttagtaccag atattttttt attatagtta atatttaatt ttttattata tcaatttatt
     1441 tatgctcttt catctatcta tattttacca cctctaaagt actgagtcat ttaattacat
     1501 cataatatag ttttatacaa ataaaatact ttatgtttca tttaatatat aaaattcacc
     1561 ttcaagaaaa ttatattata atctgacatt tttaccttat tttccaaaat atattgaatt
     1621 ttcttgcttt attttgtaaa attatgctta ggggaaatat attttaggaa aatatgaata
     1681 tataattttt agtcaactag ttattttaag tttttaaatt ttaaaataaa atatatctaa
     1741 taaaagggaa attgtattat gttttctaaa aaaaatgagg gtaacgaatt tagtaatgaa
     1801 ggaaaaggaa tctctaagaa aataattaaa ttctttaaga gcacaaaggg tattgctcta
     1861 ctggcattta tttttggtgt gttttttggc aatatatcct caccagcttg ttctgaagac
     1921 catgaggagg tcatttctaa ttaaacatca gttatagatt ctcaaaaaac agaaatagaa
     1981 actttaaata gcaaattgtc tgatgctgaa ccatggttca aaatgaaaga cgacgaaaag
     2041 aaagctattg aagctgaaaa tcaacgtaaa gctgaagaag ctaaaaaggc tgaagaagag
     2101 aagaaaggat atgatactgg tattacttat gaccaattag ctagaacatc tgatgattat
     2161 aagtacaaaa aggtaaaatt tgaaggtaag gttattcaag ttattgaaga tggtgatgag
     2221 gtgcaaataa gattcgctgt gtctggaaat tatgataagg ttgtactatg tagttaaaaa
     2281 aaatcaataa ctccttcaag agtgttagag gatgattaca taactataag aggtataagt
     2341 gctggaacta taacttatga atcaactatg ggtggaaaca taactatacc aggaatagct
     2401 gtagagaaaa ttaattaata ttgttttgta ttatagttaa tatttttgta ttatagtcaa
     2461 tatgtttaaa gatgttttta taattgcaaa taaacagtta caagactcta aattagtttt
     2521 tgcttttagc atattatcta tgttctagta actattaatt atttagtatt aatatttcca
     2581 tatatgaatt ttattataaa gtagtaaaat tatttgttta aaatttagat tatcgtcaag
     2641 aataatagat tattaaatga tagaaaaatt ttaactaaaa gtcatgtatt acaataacac
     2701 atgactttta attaaatatc aatatttatt atataaaaat aatttctgag tatcacatga
     2761 ataaattttt gtcaaacata tattctagcc atatattcca ggggctttta ctccatcaac
     2821 accaaagaaa tatataacac catcaatctc gaaaagtcca ccagctgcag ccatagcagt
     2881 atcaggcata aagtaataca tattaccatt aatagtttgc catccagtaa ctgcttttga
     2941 attattacca aagtaatata tattgccaag taaatgtagg aatctatttt gataacgtat
     3001 agcttgaccg tctatattgt tagcatccgt attagcaggt gcaaagtatt caaatccatt
     3061 aggtccttta aacactccta tctgaggtaa accatttcta aagtaaaagt ttttattatc
     3121 aataatttta taaccattcg cacctatagc tgtattaggc tcgaagtaat atctcctacc
     3181 atcaatagtt acccaaccag tagctgcttt tgaattatta ccaaagtaat atatattgtc
     3241 atgtaaatat aggaatctat tttgataacg tatagcttga ccttctatgt tgttagcatc
     3301 cgtattagca ggtgcaaagt attcaaatcc atcaggtcct ttaaacactc ctatctgcat
     3361 aataccatca gtattaaaat aaaaatgttt a
//
LOCUS       DAMKOJ010000172         3310 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000172 DAMKOJ010000000
VERSION     DAMKOJ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3310
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.181"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(57..629)
                     /locus_tag="PC592_003537"
     CDS             complement(57..629)
                     /locus_tag="PC592_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF4057460.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(658..924)
                     /locus_tag="PC592_003538"
     CDS             complement(658..924)
                     /locus_tag="PC592_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF4057461.1"
                     /translation="MKDSSRAELMRKIQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            complement(924..1133)
                     /locus_tag="PC592_003539"
     CDS             complement(924..1133)
                     /locus_tag="PC592_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF4057462.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            1402..2262
                     /locus_tag="PC592_003540"
     CDS             1402..2262
                     /locus_tag="PC592_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF4057463.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2310..>3310
                     /locus_tag="PC592_003541"
     CDS             2310..>3310
                     /locus_tag="PC592_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF4057464.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRNLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNIDIQNLLIIRDIIRAPFNDINSNLDNCFDKF
                     KESLYKKEENYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEVMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDILEDLMLYRMHEDEYKHEIENIIKMLDEDLDNEKIYINKC"
BASE COUNT         1281 a          372 c          544 g         1113 t
ORIGIN      
        1 gacacaacag taaattataa attatcaaat aatagtagtt tatataaata aaaattttag
       61 aacatttttt gagattcttc taactcgtaa gcgtccatta aagcttcgcc aaatctttga
      121 tagtgaatta tttctctttg acctaagaat tttagtacat ctataacatc aacatcatct
      181 gttaggttta taagttgata ataagttgca agtgcttttt gttcagctgc catatcctca
      241 tgtaaatcag ttacggggtt tgacataact gctataggtc ttacatcaaa tgggacacca
      301 tttgaatctg ttggataaat tccatatcca ttttgtgcat agtttgaacc aagacctgca
      361 gcttttaact cttctgggct tgcatcagaa gtcaactgat aaaccatagt acatataagc
      421 tcaacgtgag ctagctcttc tgtaccaata tctgttaaaa gtgcacgcat attaccagta
      481 ggcattgtgt atctttggct taaatatctt aaagatgcag caagttctcc atttggtcca
      541 ccaaattgag ttataagaaa tttagccatt ctagggtcac aagtttttat attaactggg
      601 tgttgtatag ttttctgata tatccacatg aattttcaat cctccaatac ttgatgtcta
      661 ataattaaat tctctgtccc aaggccaagg ttggtcagcc cattgccaag ggcatctact
      721 tggagcatac ccaaagttag ttaaaggacc atatttattt tcgtaagcat atctagcttg
      781 cgcaaattga ttacataatg aattataagt gttgatagca tttttatcat cagggtgatt
      841 gtctaaatat aagttcatat caacacatgc aaaagatgtt tcctgaattt ttctcataag
      901 ttcagctcta gatgagtctt tcattatctt ctacctcctc tatatttttt tggcttagca
      961 tataattctt tgttgtacat ttcagattct agtaagttta gttctggaaa tatagttcca
     1021 aattttaatg catcagaaag gcagtacatt tctgtaaaaa tttgattatt aatgtatggt
     1081 ctagccaaag atggaccaca attttttttg atatctctag tcttattttc caagatgaaa
     1141 acctccttgt tgtaaataga taggtaactc tatctagtgt ataatattca atcgtttaaa
     1201 aatcgttact aataataaaa tattaaatga gaaaaataaa aaagataata aaagaaagag
     1261 attatttatg ttattataag tttatgtgtt attgtaaact ataaattatt tagtaaaatt
     1321 aaagtaaaaa ttatggtatt ttgtggatga aggtagactt ttttgtaaaa tattattaac
     1381 ataaatatat gaggtgatta aatgagtgag ctatcaggaa aaggctgtga aattatagtt
     1441 ccttttgagg aaagacttcc agtaagagat atagaaaaaa gtataataaa aaaatataga
     1501 aaaaatttat ggtccaagtt tatgaaggca ataagagatt ataaattggt tgaagaaggg
     1561 gataagatag ctgtagcaat ttctggtgga aaagacagta ttcttatggc taaaatgttt
     1621 caagagttaa aaaaacatgg acaagttaat tttgatgttg aatttattgc tatggatcct
     1681 ggataccatg caaatataag acaattactt atagataatt gtgagtatct aaatatacca
     1741 atacatttat ttgattcaag aatatttgag atagcagatg aaatagcaaa agattatcca
     1801 tgctatatgt gtgcaagaat gaggagagga gcattatatt caaaagcaga agagttaggg
     1861 tgcaataaac ttgcattagg tcatcattat gatgatgtaa tagagacaac aatgcttaat
     1921 ttattgtgtg ctggaaactt taaaacaatg cttcctaaac tcaattctac taattttgaa
     1981 ggtataaaaa ttataagacc actttattat ataagagaag aacatattat aagatttatt
     2041 caaaatagtg ggatatggcc attaaattgt gcatgtatgg ttgctgctaa aaaaacaggc
     2101 aataagagat atgagataaa agatttaata aagagtttag aatcaaattt taaaaatgta
     2161 gaaaagtcta tatttaaggc agcagaaaat gtaaatcttg actcagtact tggttggcaa
     2221 aaagatgggg agaaacattc tttcttagaa aattttgaat aaaaataatt aaaaagaatc
     2281 actataaaca attagaaagg gtgtttatat tgaaaagagt atatatagat tttgaaatga
     2341 atatgccaaa ttctaaatca aaaagagcag tatttaattc tgatataatt gcaatcggag
     2401 cagttatgta tgatgaaaaa acaaaaaata ttgataaatt taaatcttta ataagaccag
     2461 taagtaatga ggaattgtat cctcatatac aagaattaac acatatatct tctgaagaat
     2521 tgaagagtgc accaagttat gaagaggtca tgagaaagtt taaaaaatgg ctgggcatat
     2581 tttctgatat taaaggaata tatacttttg gtaatttaga tttgacatgt ttcaataaca
     2641 cagatatgag aagtgctaaa aaaaataatc atccaaggtt tgtaaacaat attagaaatc
     2701 tatttgtaga tataaaagaa aaatatataa attgtggtat gagatgtatg aactatatat
     2761 cattgaaaaa tttacttgaa tttgttaatt tagagtttag tggagatgct catgacccac
     2821 taaatgatgc atataattta tttattttgg acgaggcaat tacaaataat atagacatac
     2881 aaaatctttt gataatacgt gatataataa gagcaccatt taatgacata aattctaatt
     2941 tagataattg ttttgataaa tttaaggaat cactatataa aaaagaagaa aattacaata
     3001 ttgtagattt ttcagttgaa ataataaaaa ctgtgagaat gtacttatta acaataatag
     3061 atgtaaatat acaaaattta gaagttatga aagatataag taaaaaaatg gatactatag
     3121 ataaattgaa agatatagag gaaggctatt tttatttatt agaagatgta tattttgata
     3181 tgaaagatat attagaagat ttaatgcttt ataggatgca tgaagatgag tataagcatg
     3241 agatagaaaa tataataaaa atgcttgatg aagacttaga taatgaaaaa atatatataa
     3301 ataaatgtaa
//
LOCUS       DAMKOJ010000173         3152 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000173 DAMKOJ010000000
VERSION     DAMKOJ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3152
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.182"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            155..301
                     /locus_tag="PC592_003542"
                     /pseudo
     CDS             155..301
                     /locus_tag="PC592_003542"
                     /inference="COORDINATES: protein motif:HMM:NF013180.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            391..489
                     /locus_tag="PC592_003543"
     CDS             391..489
                     /locus_tag="PC592_003543"
                     /inference="COORDINATES: protein motif:HMM:NF013180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4057465.1"
                     /translation="MSVSIGISLYSKYGEQFYKLYRHADSALYRVK"
     gene            687..2507
                     /locus_tag="PC592_003544"
     CDS             687..2507
                     /locus_tag="PC592_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF4057466.1"
                     /translation="MKKKYDFLIYAAIWLVAIIIFIFSLYHSIEHIKIINYTGIISSE
                     TQKVTKQELNNKRNDKLISQLDSILIELRTGNGKHRLQRCDNKEFQEKLIEMDAMWDS
                     MKKEIRKVRNGGSGDKLYKLSEKYSSLSNQVVFISEKHSDIKLHFFATVLFIYLIIST
                     ISLLIWEYYNKRKFDKIFYTDNLTKIKNQVAFENRAIEILSHAYNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLVIVANVLAKTFNTKETCARVGSDNFVILAKYRESLLYEISKT
                     LTDAIISELNMNVTQTISFCIGAYLVEIEKSNYKYINSIMDKANIAHKVSKMRGISST
                     VWYNENLLKQLQMENSIYNHMYKALENEEFQMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDQFIPLFEKSGFIIELDFYMLKKACSFIKKTFMKKNKYTYPIAVNFSRVTIY
                     QNDFYQRFLDTVREYEIPFKYIEIEVTESAFNEISEPVISILDKLEKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKEKFNRAKVYSIIKCIIEMSHSIDMSIVCEGIET
                     KKDLEFLKTVKCDLGQGFYFSKPIEEKEFFNKYVMDKQYN"
     gene            complement(2592..>3152)
                     /locus_tag="PC592_003545"
     CDS             complement(2592..>3152)
                     /locus_tag="PC592_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057467.1"
                     /translation="NQFERSYDIGIFKNEQSIHKFIEKIPFVKKDSSNFNYTNYYMEF
                     EDIPEYYEVNFNNYLYIITKFSFIPDGTEIFFTWDEIHCWDEKVATDKTFINGETLVD
                     SYSFPNNEVKNYIQKRESLYRETKKYYKEKGLKIKRHALGSEDGEYVELVDDSILYLL
                     DVHAVEIWEQSKNIEEFLYKYKKYFE"
BASE COUNT         1218 a          323 c          457 g         1154 t
ORIGIN      
        1 ataaacatag gcgtaattca agtaaaattt caaaaaaaag gaatatattt ccataatatg
       61 ataaaataaa ttcaaagagt taaattctag tcaaatatta ctttaattat ttattaaaat
      121 agattagata ttccatattc aataccattg agttgatgtg tataatttta aatatgtaaa
      181 ggattctatg gggtatgtat ttggagataa aatattaatt gatttagctg aatgtttaaa
      241 aagatatttt agagaaacgg acactgttgg tcgtgtagga ggtgatgagt ttataatata
      301 gtgaagaaag agaaagtgta aaaaataaag gctttgataa tattaaaaag gctggacaat
      361 aagtttacgt atgatgaatg atattttgag ataagcgtaa gtataggaat ttctttatat
      421 tcaaaatatg gagaacagtt ttataagtta tatcgtcatg cagatagtgc tctatataga
      481 gtaaaataag aaggaaaaaa cacgtattgt atgtttttct atctaaaaat aaaatctata
      541 ttataaagga ttgttctatc ttaggtatat aaatgattga gatatttaag ataaatacat
      601 attactgcaa agcattgata attatttttg atgagagatt gattatttgc aaattatata
      661 gatacattat aattgaggga ataataatga agaaaaaata tgatttttta atttatgctg
      721 ctatttggct agttgctatt attattttta tattttctct ataccatagt atagagcata
      781 ttaaaattat aaattatact ggtattatta gcagtgaaac tcaaaaagtt actaaacaag
      841 aattaaataa taaaagaaat gacaaattga taagtcaact agatagtatt ttaatagaac
      901 taaggacagg caatgggaaa cataggttgc aaagatgtga taataaagaa tttcaagaaa
      961 aattaattga aatggatgct atgtgggatt ctatgaaaaa agaaattaga aaagttagaa
     1021 atggtggttc aggtgataaa ttatacaaat tgagcgaaaa gtattcttcg ttgtctaatc
     1081 aagttgtttt tatatctgaa aaacattctg atataaaact gcattttttt gccactgtat
     1141 tatttattta tcttataatt tcaacaataa gtctcttgat ttgggaatat tacaataaaa
     1201 gaaaatttga caaaatattt tatactgata atttgacaaa aataaaaaac caagttgcat
     1261 ttgaaaatag agctattgaa attttatctc atgcgtataa taaggagtat gtgctactaa
     1321 acattgacat tgataatttt aaatatatta atgatacaca tggatatgaa tatggtgata
     1381 aagttttagt aatagttgca aatgtacttg ccaaaacttt taatactaaa gaaacttgtg
     1441 caagagttgg ttcagataat tttgtaatac ttgcaaaata tagagaatct ctcttatatg
     1501 agattagtaa aactctaact gatgcaataa tatccgaatt aaatatgaat gtgacacaaa
     1561 ctatatcttt ttgtatagga gcatatttag ttgaaattga aaaatcaaat tataaatata
     1621 taaattctat aatggataag gcaaatattg cacataaagt aagtaaaatg agaggaattt
     1681 catctacagt gtggtataat gaaaatctat taaagcaatt acaaatggaa aacagtatct
     1741 ataatcatat gtataaagca ctagagaatg aagaattcca gatgtatttg caaccaaaat
     1801 ttcaaatatc ttctttaaat gttgtaagtg cagaagctct tgtacgatgg ttttctccag
     1861 aacttggttt tttgtcacca gatcaattca ttccactatt tgaaaaaagc ggatttatta
     1921 ttgaattaga cttttatatg ttaaagaaag cttgttcatt cataaaaaaa acatttatga
     1981 aaaaaaataa atatacttat cccatagcag tcaatttttc aagagttact atttatcaaa
     2041 atgatttcta ccaaaggttt ttggatactg ttagagaata tgaaattcct tttaagtata
     2101 tagaaataga ggtaactgaa agtgctttta atgaaatatc tgagccagtt atttcaattt
     2161 tagataagct tgaaaagtta ggtttcttaa tttctatgga tgattttggc tcaggatact
     2221 cgtcattaag ccttttatgt tctttatcga ttaatggatt aaagttagat aaaagcttac
     2281 ttaaagagaa atttaataga gcgaaagtat atagtattat taagtgtatt atcgaaatgt
     2341 cacatagtat agatatgtct attgtatgtg aaggtattga aactaaaaaa gatttagagt
     2401 ttttaaagac agttaagtgt gatctagggc aaggatttta tttttctaaa cctatagaag
     2461 aaaaagaatt ttttaataaa tatgtaatgg acaaacaata taattagttt tattgttaat
     2521 cttatgcatt gagttatttt atatcttatt aaatagctca atgcatagtt atgcaggtca
     2581 aaaaacataa atcattcaaa atatttctta tatttatata aaaattcttc tatatttttt
     2641 gattgttccc atatttcaac tgcatgtaca tcaagtaaat aaagtatgga atcatccaca
     2701 agttcaacat attcgccatc ttctgaacca agtgcatgtc ttttgatttt caatcctttt
     2761 tctttatagt atttttttgt ttctctatat agtgattctc gtttttgtat atagtttttt
     2821 acttcattat ttggaaaact atatgaatct accaatgtct caccatttat aaaagtttta
     2881 tcagtagcaa ctttttcatc ccagcaatgt atttcatccc aagtaaaaaa tatctcagtt
     2941 ccatctggaa taaatgaaaa tttagtaata atatacaaat aattattgaa atttacttca
     3001 taatattcag gaatatcttc aaattccata tagtaatttg tataattaaa gttactacta
     3061 tcttttttta caaatggtat tttctcaata aatttatgta tagattgttc atttttaaaa
     3121 attcctatat catagcttct ttcaaattga tt
//
LOCUS       DAMKOJ010000174         3067 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000174 DAMKOJ010000000
VERSION     DAMKOJ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3067
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.183"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            185..562
                     /locus_tag="PC592_003546"
     CDS             185..562
                     /locus_tag="PC592_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4057468.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDTTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            555..1589
                     /locus_tag="PC592_003547"
     CDS             555..1589
                     /locus_tag="PC592_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF4057469.1"
                     /translation="MNNYMIYVFENLIKTTIVCSLGICLLLFLKRYVFKKFSKRFNYY
                     IWLVMVFRMLLFLFNYTVIYEVKEPKENTVGNNITQIDISTDNNLVLYLAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYSIEDNDVNCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSRDELSWILKHELMHFKNKDILIKFLVLSVKIIYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKSIKLSRNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKSGILVLLILFTLFSVTYFNFESISFDNSNSLRNIGILEKSGADLKE
                     ENDISMRIVN"
     gene            1655..2242
                     /locus_tag="PC592_003548"
     CDS             1655..2242
                     /locus_tag="PC592_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF4057470.1"
                     /translation="MKNLKKILIVTGCLTLISTSLVFANTTTDVDTSKDDDSVISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKDDIIFVNKDSIDVNDIENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLDVSDTVVGYNRVESGNPVHLVQLLCRTLDGSSIKDDSEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(2458..2810)
                     /locus_tag="PC592_003549"
                     /pseudo
     CDS             complement(2458..2810)
                     /locus_tag="PC592_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1175 a          288 c          471 g         1133 t
ORIGIN      
        1 gtaattaaat atgtaaaaag gaaaatattt aaatagatat attttaaaat ctaactttta
       61 atattgtaaa aaaattagaa aattaacaaa aaatacaaaa attcacattt ttttcataaa
      121 gtgtttgact aaaaaattca catgttgtag aattaaggta gcaagagttt tgagggaggt
      181 gtaaatgatg ataagaaaaa taccacaagc agaactaaaa gtaatgaaat tcatttggaa
      241 agtagatact acagtgacat caaaagatgt tattgaagct atggaacaaa aatatggctg
      301 gaaacaaact actacactga cgcttttatc taggctggta aaaagagggt tcttagatgc
      361 tcaaaaaata gacagatata cacattatac aataatagta aaacataaag attatttaag
      421 ctttgagaca aaggatttcc taagtaatat acatgatgac tctttgaaaa gtttaatttc
      481 agcattacat gatgatgaaa atataggtaa agataagcta gattttttag aaagttattt
      541 tgataattta aaagatgaat aattatatga tatatgtttt tgaaaatctt ataaagacaa
      601 ctattgtatg tagtcttggt atttgtctat tattattttt gaaaagatat gtgtttaaga
      661 agtttagtaa gagattcaat tattatattt ggttagtaat ggtctttaga atgttacttt
      721 ttctatttaa ttatacagta atatatgaag taaaagaacc caaagaaaat acagtaggaa
      781 ataatattac acaaattgat atttctacag ataataatct tgtgctgtat ttagcttatt
      841 tatggttatt tgtaactata gtcattgcag tttatacatt tataaagtat acaagattta
      901 aaaatcttgt tgttgatgta tcttatagta ttgaagataa tgatgtaaac tgtatctaca
      961 aaaacttgtt gaaagaatta aatataaaaa agaaaattga gttaagaggt tctgatgaat
     1021 tgataagtcc agcaggcatg ggattattta aatcttacat attcttacca gactatcctt
     1081 atagtagaga tgaactaagt tggattttga agcatgaatt aatgcatttt aaaaataaag
     1141 atattttaat aaagtttttg gttttgtctg ttaaaataat atattggttt aatccacttg
     1201 tttatataat gagcaataaa gtaaatctag attgtgaatt atgttgtgat gaaagtgttt
     1261 tgactgattg ttctttaaaa gataagaaag aatatgcatt agcacttata aagtcaatta
     1321 aacttagtag gaattataat agtggtattt taacaacaga gtttaataag acaagtttag
     1381 aaaagagact tgacagtatt gttaagaaaa aaggtaaaag tggaatattg gtgttattga
     1441 ttttgtttac attattttca gttacatatt ttaattttga aagtattagt tttgataatt
     1501 caaactcttt aaggaatata ggtattttag aaaaatcagg agccgatctt aaggaagaaa
     1561 atgatattag catgagaatt gtaaattaat agattaatat atgtaatgaa aaggtatatt
     1621 gtcatattat taataaatta ggaggaatta tgaaatgaaa aatttaaaaa aaattttaat
     1681 agttacaggc tgtctaactt taatatctac tagtttggta tttgcaaata ctactactga
     1741 tgtagataca tcaaaggatg atgattcagt aataagttca tgtactataa ctggttatga
     1801 atttacttat gaaaacgcac cacaatctgt aaaatttgat tatgaaaaaa aatgtgaagc
     1861 gctaaatata aaaccatcta aagatgatat aatttttgtt aataaagatt ctatagatgt
     1921 aaatgatata gaaaactatg ttgagccaaa agcatatatt attagatata aaaaaggtta
     1981 tgtttttgaa gttactggac ctaagagtta tacactagat gtaagtgata ctgtagtagg
     2041 atataatcgt gttgaatcag gtaatcctgt gcatttagtc caacttttat gtagaacttt
     2101 agatggttca agtattaagg atgatagtga atttggacct gctacatata atgcagttaa
     2161 gtcacttcaa ggaagacttg gattaacaag agatggaatt gttggaagaa gtacttggga
     2221 tgcagctgga agacgtcttt aaaaaagaga gctattgcac agataatttt aaattgttaa
     2281 atctgtaaac atttatgtgt attctttaaa taaaaatttg ttttttaagt gataattaaa
     2341 tttttactga tagggctatg gctttaaaaa tcatagcctt atttcgatgt tttttcgttt
     2401 ttgtaaaatt attgccattt taagaaaatt tattgatttt tttgaaatat ttctttatta
     2461 atttagagtt aaatttcttt ctttaaaata aatacttaaa tgagctaaaa cttgagtcca
     2521 atttctaatt ttatgagacc gtttttcaaa aatatccata gttgctaagt atagtgattt
     2581 gtgcaaagaa tcatctgaag gaaaaataga cttcgattta gtaacttttt ttaataatct
     2641 attgtaactt tccattgagt ttgtagtata tatcaatgtt cttatccatg aggatattta
     2701 aaatatgttg cgaactcatt ccaattgctt cgccaatttc ttaatgctac ctcttctgta
     2761 attgcatcat atactttctt taatgagttt ttttacattt cgtttttgtt aaacataaaa
     2821 agtgagcgcc ttcctttgta tagtgatatt tgatatttta attattatta ctttttagaa
     2881 taatacacac tttattttaa agaccctgaa aatgatattt ttatacatta tatttgttat
     2941 gcataatttt acttagaaca taaacttata taaaacaata aaaagtatat atattagata
     3001 agtaaaaaaa gcgttcttac agaacaaatt taatttgctc atgcaaaagc tcttttttta
     3061 taattta
//
LOCUS       DAMKOJ010000175         3031 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000175 DAMKOJ010000000
VERSION     DAMKOJ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.184"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            223..363
                     /locus_tag="PC592_003550"
     CDS             223..363
                     /locus_tag="PC592_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057471.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(360..731)
                     /locus_tag="PC592_003551"
     CDS             complement(360..731)
                     /locus_tag="PC592_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057472.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTNISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            1275..1532
                     /locus_tag="PC592_003552"
     CDS             1275..1532
                     /locus_tag="PC592_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057473.1"
                     /translation="MIIIRSQDKTNLMYINQIKIDGSQVYAVFESNLDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITFNKVRYNVNKIFQMPVK"
     gene            complement(1642..2322)
                     /locus_tag="PC592_003553"
     CDS             complement(1642..2322)
                     /locus_tag="PC592_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF4057474.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVVIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSDLFRVDEINLIPFDSVGILTYILNVIMFMPLGFLL
                     PLIWKNFRNIINVLLTGLGFSLAIEFCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            2579..2878
                     /locus_tag="PC592_003554"
     CDS             2579..2878
                     /locus_tag="PC592_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057475.1"
                     /translation="MKWIKWYSFTCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKNNPVDGTTTIYYSYDNSTHIVRLSHPEDSSREINWDKVSNISFD"
BASE COUNT         1216 a          328 c          352 g         1135 t
ORIGIN      
        1 caagattcta caataataga tttttttgtt attattacga gttttttatt gcaactgtag
       61 aataaaagta ttattatata attaagataa ttatctaggg aaattttgga taatcaaaat
      121 atattttata aaatcaaaat acaattacat aaactttatt aaaaatttgt tgggaatttc
      181 tgactaacat taagaacgta agtttgttgg gggatggtat atgtggaaaa gtcaaacact
      241 actgttacaa aaaaagaaaa aattgaagat ataggaatga aattagaaca tttattgagt
      301 gaagatatta ctttttatga attattactt gagattttgt ataaagaaaa agaagagaat
      361 taattctctt ctttaaggaa tctttttaaa taggcattat caatcatttt ttctatagct
      421 tctctatctt ctttttcaag agaatatatt ttttctaaaa gtttttttgt tttttcactc
      481 actgataagt tctctatgat taatttatct tctttgctta tgtttgtgtt atcatttacg
      541 cctaataaat aatctgttga tgtttctaat gcttttgcta atctcactat tatttcactt
      601 ttaggttctc ttaaattatt ttcataacgt gacaagctag cctcagttat accgacttta
      661 gtagcaagtt ctttttgatt tatatctaat tcttttcgta aatttgctat tctatctcct
      721 aaactttcca tatgtacatc actccttacc gaaattataa gttattttta taaaaagtaa
      781 aataaaatta ccaaaaatat aaaaaaaaag aattaaaata agaaaatata ttgaaaatta
      841 ccatttgtat atgtataata agaattatac aaatggtaat ttgatgagag gtggtatttt
      901 gaaataagaa accgaattaa ttagtaaaca tatagaaagt tttgaatact gttacttgag
      961 atataaacaa tatgcataaa aatttttgaa agtaaaatta ccaaatgtat aaaataaatc
     1021 agtagcatag atagtttgat gctttaatag attatgtaat ttagttataa tagccaaaaa
     1081 tgcaatttac caataaaaca aggtattata aaaaaagtat tctttaaggg aactttttat
     1141 tagatatgca attgatacaa ataatcgtat taaaaaataa aatactaagt ttaaaaattt
     1201 aaataatcta gaaatcaatt ataaaatatt atttcttaga aactaaaatt aattaagtaa
     1261 atggaggaat tgacatgata ataattagaa gtcaagataa aactaattta atgtacataa
     1321 accaaattaa aatagatggg agtcaagttt atgcagtatt tgaaagtaac cttgatactg
     1381 taaaaatagg agattatgaa aataatacaa gagctataca agtattggat aatatacaaa
     1441 acttcattga aaatggaaca aaatatgatt atataacatt caataaagtc agatacaatg
     1501 ttaataaaat atttcagatg ccagttaaat aatgagtgtg cattttagtt taataactaa
     1561 agcccgcttt cttttgaagt atgaaagagg gctttacaca tttgtaaata ttgaagtaca
     1621 cttgttttgt cagtaaatta tttaataagg tataatggac caattaaaca ataaaaattc
     1681 tcctaaaaca gcaagtatta aatatataat agcttcattt ttataaagag aggtaatttt
     1741 tttgcttata tcatcatcaa ttgtaatagc aatttcatct tgaataatat ttttatatat
     1801 agatggaaaa atatcttttt tctttataag attaaataaa ttatttacac ctacccatat
     1861 aaaatatcct aaaacagcac ctaatgtgtt catcattaaa tcatcaatat ctgtagctct
     1921 taagttaaac aattgacaaa attcaattgc taatgaaaaa cctaatccag ttaataaaac
     1981 attgataata tttctaaaat ttttccaaat taaaggtagt aaaaatccta aaggcataaa
     2041 cataattaca tttaaaatat atgttaaaat gccaactgag tcaaaaggta ttagatttat
     2101 ttcatcaact ctaaaaaggt cactatacct tcctatatcc catatgctac caataccagc
     2161 tttactaagt gctaggtata tatataataa aaaaatatat acccatacta aatgtatcac
     2221 tacatttttt tcaactttca aattttttct ttttataaca actatttggt atattaagca
     2281 tggtaatata acacaaataa atgaataaaa tgtccatatc attttatttt gtcccctttc
     2341 aaatttatgt ttttagtttt ataagtacta tctttatatt aagcggtaag ttttaaaaat
     2401 cttttaataa aatcttaaaa atttattaat ttataaaata tattatcaaa attaaaaagt
     2461 atatataatc aagttttcta caactatata tacatgtaga aaaattttat cgtatgtata
     2521 aatattataa atatatggaa ataataatag tatattttgg taaagtagga ggaattttat
     2581 gaaatggatt aaatggtata gttttacatg tatatgtatt tttatagtag tagcttttta
     2641 tatgtttata tttcctaata aaatagaaac tattgatact tcatctgcat atagttttgt
     2701 tgaaaagaaa gtaccaaata gtgctgtgta tcaaggatac aaaaataatc cagttgatgg
     2761 tactactaca atttattaca gctatgataa ttcaactcat atagttagat tatcacatcc
     2821 agaagactct tcaagggaga ttaattggga taaagtttca aacatcagct ttgattaatc
     2881 tttaatattt ataaaagtct atatgtataa ggtaaatata ttattaatct tattcatagt
     2941 tgagcacttt ctattataga agtgcttttt ctgatttata gcataaaata ttactcaaca
     3001 atttgtaaaa tatattagtt tataaaatat a
//
LOCUS       DAMKOJ010000176         2930 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000176 DAMKOJ010000000
VERSION     DAMKOJ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.185"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(311..511)
                     /locus_tag="PC592_003555"
     CDS             complement(311..511)
                     /locus_tag="PC592_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF4057476.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(736..912)
                     /locus_tag="PC592_003556"
     CDS             complement(736..912)
                     /locus_tag="PC592_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057477.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFIIEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(966..1055)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(1338..1538)
                     /locus_tag="PC592_003557"
     CDS             complement(1338..1538)
                     /locus_tag="PC592_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057478.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(1540..1890)
                     /locus_tag="PC592_003558"
     CDS             complement(1540..1890)
                     /locus_tag="PC592_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HDF4057479.1"
                     /translation="MIQKKFFMGFCGFIGFLSLRYFSSGNIADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKSAMAFTGQFAIIELFILWCITIVSRNVELMCVLLSIAYAIT
                     LNVYAIKLYILEEK"
     gene            2252..2473
                     /locus_tag="PC592_003559"
     CDS             2252..2473
                     /locus_tag="PC592_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057480.1"
                     /translation="MNKYNKTLKKNKIFQGISRKATFFDNSPMKNSFGVMKRECIIKK
                     YKQLFESFFVIIKRIMRGLRNLDMKVLLS"
     gene            2404..2781
                     /locus_tag="PC592_003560"
                     /pseudo
     CDS             2404..2781
                     /locus_tag="PC592_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427607.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
BASE COUNT         1121 a          351 c          363 g         1095 t
ORIGIN      
        1 aaatatataa atatgtttta attacttttt attgataatt tattagaatt gaatagaaga
       61 gaaagtatat gtgtttagga gttagttgaa agttttggta tgttacaatt aaattattct
      121 attatatagt ttaactaaaa aaatatttgt aagtttaagt atatacttta taaatatttt
      181 tttgtgagac ttattttata aaaagtgttt agactaagta ttctcttatt aagggatttt
      241 tttacttatt tacagaatat tatcaataaa aaaaagaccc tcaaaagagt ctttccgaaa
      301 aatctatata ttataatata gttatatttt ctgcttgagg acctctagcg cctttaacta
      361 tatcaaagct tactttttga ccttcttcta atgatttaaa tcctgaagtt tgtatagctg
      421 agaaatgagc aaatacatca tctccacttt ccattgatat aaatccaaat cctttttcat
      481 tattaaacca ttttactatt ccattattca ttaaaaatac tcctattaac ctatatcaag
      541 atatacttga tttacttgtg tattaccaca aatactattg tatcatagat taatagaaat
      601 gtctatttaa ttataatttt tagttaacat ttttatttat tcttaatatg aaaataaatt
      661 taaacatttt atattaccaa tatattaatg taaatgtaga taaaactaaa aagggttttc
      721 tagaaaaaaa tctgtctaat tatacttact taccaatacc atcacttgat gcaagcaaga
      781 ttctacaact ttttctccat actctattat aaaatcatct aactgtgtat ctataaaatc
      841 acaataatca tatgaactac caatataagc agttaacata tgtgtacatt tatccatttt
      901 atctctaaac ataatgtatt tatctcccta aaaaactttc atgaaaaaca aaaagaaaat
      961 atctttttgg caactggctg acataactta ttttataagc gttagtccct atagctttgc
     1021 gtcactaaat ttctctagtt ttgccgattt agttttattc tacaaactaa taatacaata
     1081 gaattagtta ttattcaaca tatctagctg aaaaattaat aaatttatat attaatgtta
     1141 aattattttt tcaatattaa aaagagaggt gaacacacat tgataatttt ttacaaggta
     1201 tactagtaaa ttcagttgcc agtttaatat tttacttaac taataaatta ttaaaaaaat
     1261 aaaaagcccc tctgggagga gtgactaaaa attgaattta agtttgaatt taaaacgtgt
     1321 ttttaataat gcaaaaacta atcaaaaata aacaattcat caataggagt atctactatt
     1381 tttgatatat ctatcgctaa ttttaaagaa ggattatact tacctgcttc caaacgcata
     1441 atggtttctc ttctaactcc tactttttct gctaattgtt cttgagttaa ttcttttaat
     1501 tgtctgtatt tttttagatt acaaatgaat ttgggcatgt tatttttcct ctaaaatata
     1561 aagttttata gcataaacat ttaaagtaat tgcatatgca attgatagta aaacacacat
     1621 taattctaca tttctagaca ctatagtaat gcaccataaa ataaataatt ctataatagc
     1681 aaactgtcct gtaaatgcca tagctgattt ttcatcttgt acataccttt catctgcttt
     1741 atcaccgttt atttttgcta taataaagtt tgagaaaaaa gcaaaaaagc caatatatgt
     1801 aaggtcagca atattaccag atgaaaaata tctaagactt aaaaatccaa tgaaaccaca
     1861 aaaacccata aaaaattttt tctgaatcat ttcttatcct ccttagtatt ttaaaaagag
     1921 atatatttgt atctttatga tataaatata tctctttttt atttttttgt caatataaaa
     1981 gcagtgttat acaatatttg taatgtacca taattactag accaaaaatc taatgattga
     2041 ggtgtttatg tatgactaaa tacgatttta aatttaaatt aaaagtagct aaattttatt
     2101 taaatagaga agaaggagaa gttatgtcat tcagtgtctg atatatggct aactttaaat
     2161 caatagtgat gttttaaata aagctatcaa tattacaaag gattgtcctt atagaaggac
     2221 ttttaactca aaccaaggtt ggccatataa aatgaataag tataacaaaa cacttaagaa
     2281 aaataaaata tttcaaggta tatctcgtaa ggctacattc tttgataact ctcctatgaa
     2341 aaattcattt ggagtaatga agcgagaatg tattataaaa aaatataaac aattatttga
     2401 aagttttttt gtaataataa agaggattat gagggggcta agaaacttag atatgaaggt
     2461 attgctaagt taattgtaga aggtgtatta aataaaaata taaataatga gggagttaaa
     2521 cagatgtaca aacatacaat agtttatgat ggtgaagttg ataaaatccc tgcaactgtg
     2581 cttggttggg gttatggttc aaataaaatt ttaatatgta atataaaaga ttatgtacca
     2641 ggaagaactg aaaatcttta tgttgttgtt ggtggagcat gtgagaagat aggttctata
     2701 actaaagaaa actataccat gataaagggt agtgatagat ttgatacact ttacaaagta
     2761 ttagatttta taaatagata gattaaaagg tagcaactag taggttgtta ccttcctttt
     2821 tctagctttt tatatctgac aatttttgtt atttgtataa ctataaagtt aatataagaa
     2881 gatatttgta agtaagagta tatgaaaata taataattta tgtttaataa
//
LOCUS       DAMKOJ010000177         2901 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000177 DAMKOJ010000000
VERSION     DAMKOJ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2901
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.186"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            27..2384
                     /locus_tag="PC592_003561"
     CDS             27..2384
                     /locus_tag="PC592_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDF4057481.1"
                     /translation="MGNLNLKRYNCDIKMGLSSEQIQSRIDNNLVNVFDNGKTKTYKQ
                     IFKDNVFTLFNLINIILVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIRDKEKKEIDVQELVLDDIMILKTGNQICADSKVLDGRLEVNESLITGE
                     SDIVIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKVVGIIIIPLGLILFAKQHFGNGDSIVTSIVGTVAAVNGMIPEGLTLLTSIALAL
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDVVMLEELDIDDIMG
                     NICNALKDDNATLNAIRDKYSILDTHKVKNLIPFSSERKYSGVIFEGEGTYLLGAFEF
                     IFKDKYKELKTEVEKYSKKGNRVIVLAHSNSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPMTVSEVARKAGLKTAGNFIDATTLKNDEDIYEAVDK
                     YNVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRTASLFLVKTIFSFFLSILTLFFFSRQYPF
                     VPIQLALIGAVTVGIPSFFLALEANRGRISGNFLLNILKNALPGALCVTINVIIVYNI
                     VEYLGYNSSVFSTMCAILTGVCGLLILRQQCLPFNKERIFLIVSMTIAFIVGILFLGG
                     LFSFVALSKQLILITVVLAVLMPIMIKVMRFVLDEILGAIVPNLN"
     gene            complement(2469..2786)
                     /locus_tag="PC592_003562"
     CDS             complement(2469..2786)
                     /locus_tag="PC592_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDF4057482.1"
                     /translation="MNEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEILAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1094 a          332 c          479 g          996 t
ORIGIN      
        1 aattgttaaa ttaaaaggag cagagtatgg gtaatcttaa tttaaaaagg tataattgtg
       61 atataaaaat gggattaagt agtgaacaaa ttcaaagtag aatagataat aatttagtta
      121 atgtatttga taacggaaaa actaaaacgt ataaacaaat ttttaaggat aatgtgttta
      181 cactttttaa tctaataaat attattttag tatgtttact agtttcagtt ggttctttta
      241 aaaatacctt atttatattt attgctgtaa ttaatactat tataggcgta attcaagaaa
      301 taagagctaa aagattgctc gacaatctat ctgttatagt ttcaaataag gtatctgtta
      361 taagagacaa agaaaaaaaa gagattgatg tacaggaatt ggtactagat gatattatga
      421 ttttaaaaac aggaaatcaa atttgtgcag attcaaaagt tctagatgga agattagaag
      481 taaatgagtc tttaattaca ggagaatctg atattgtcat aaaaaacaaa ggtgatttct
      541 tatattctgg tagctttgta gtttctggag aagcttttgt aagagttgaa aatataggaa
      601 aagataacta tgcgaataag atagctaatg atgccaagat ttctaaaaaa cataattctc
      661 agcttagaaa ttcattaaat gcaatattaa aagttgtagg tataataatt attcccctag
      721 ggcttatatt atttgcaaag caacattttg gaaatggaga ttctatagtt acctctatag
      781 taggaactgt ggcagctgta aatggaatga taccagaagg actgacacta cttacaagta
      841 ttgcactggc tttaggaact ataaagcttg caagtcataa aacgttagta caagaattat
      901 actgtgtaga aactcttgct agggttgaca cattatgcct tgataaaaca ggcactatta
      961 cagagggtaa aatgcaagtt gatgatgtag taatgttaga ggagttagat attgatgata
     1021 taatgggaaa tatatgtaat gctcttaagg atgataatgc aacactaaat gcgataagag
     1081 ataaatacag tattttagat acacataaag ttaaaaattt aattcctttt tcatcagaaa
     1141 gaaaatatag tggtgtcata tttgaaggtg aaggaacata tttactagga gcatttgagt
     1201 ttatttttaa ggataaatat aaagagctta aaacagaagt agaaaaatat tctaaaaaag
     1261 gcaatagggt aatagtttta gctcatagta attcttatat ggaagacaac aatattcctg
     1321 aagacataaa accactagca tttatattaa tattggataa aattagagat gaagctaagg
     1381 aaacattaga atttttttat aatgaaggtg tagatataaa aattatatct ggagacaatc
     1441 caatgacagt aagtgaagtg gctagaaaag caggtcttaa aacggctggt aattttattg
     1501 atgcaacaac acttaaaaat gatgaagata tatatgaagc agttgataaa tataatgttt
     1561 ttggaagggt aagcccacag cagaaaaaac aaatgatttt agcattgaaa aaacaaaatc
     1621 atacagtagc tatgactgga gatggtgtaa atgatgtgct agcacttaag gaagctgatt
     1681 gtagtatcgc tatggcttct ggaagtgatg ttactaaaaa tgtttctaat ttggtattgt
     1741 tggattcaaa ttttgcatca atgccaaagg ttgttatgga aggaagaaag gtaattaata
     1801 atattcaaag aacagcttct ttatttttag taaagacaat tttctcattt ttcttgtcga
     1861 tattaacatt atttttcttt agtagacaat atccatttgt gcctatacaa ctagctctaa
     1921 ttggcgctgt aacagtgggt ataccatcat tcttcttagc tcttgaagca aatagaggta
     1981 gaatttcagg taacttttta ctcaacatat taaaaaatgc tttaccagga gcactttgtg
     2041 tgacaataaa cgtaattatt gtttacaata tagttgaata cttaggttat aattcaagtg
     2101 tattttctac aatgtgtgct atattaactg gtgtgtgtgg acttttaata ttaagacaac
     2161 aatgtttacc atttaataaa gaaagaatat ttttaattgt aagtatgact attgcattta
     2221 ttgttgggat tttattttta ggtggattat tctcatttgt agcattgagt aaacaattaa
     2281 ttctcataac tgtggtacta gcagtattaa tgccaataat gataaaagta atgagattcg
     2341 tattagatga gatactaggt gcaatagttc caaatttaaa ttagatttaa taatatataa
     2401 aaagagcagt cttcattgaa ctgctctttt tagatgtgtt taattttatg taagaatatg
     2461 tagctttatt aatcagctat atatgagcaa cagtagtcaa cgacttcatt aacttttaaa
     2521 tcaaaacttg aatcactagg aacattaaat ttttgacctt ctttataagt tacaaactca
     2581 ttgcttccag gcaattttac atccatactt ccagcaagta tttccattat ttcttcttct
     2641 ctagtagaaa aagtatattc tcctggcaac attaatccta aagtttttct ctctccatta
     2701 ggtagtatta ttactctact gcttacttta ccatcaaaat aaacgtttgc cttttttact
     2761 gcagtaacat tcttaaattc attcattaga taaaacctcc aaaattattt gtatatatac
     2821 attatataaa aataatataa aaaatgctat atatttacaa ataaatttag tatttgttaa
     2881 aaaaattaat aaaaataaaa a
//
LOCUS       DAMKOJ010000178         2888 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000178 DAMKOJ010000000
VERSION     DAMKOJ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2888
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.187"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..655
                     /gene="pgmB"
                     /locus_tag="PC592_003563"
     CDS             <1..655
                     /gene="pgmB"
                     /locus_tag="PC592_003563"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF4057483.1"
                     /translation="DGVITDTAYYHYMAWKKLAHKIGINIDTKFNESLKGISRMESLD
                     RILEFGNKKDLFSKEEKLKMSEEKNNYYIALINDITSSDILPGIESLLIDVKSNNIKI
                     GLSSASKNAINVLNHLGISDKFDFIANAAKCKNNKPHPDIFLMSAKGLNVNPKNCIGI
                     EDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYNEYMVRRII"
     gene            652..>2888
                     /locus_tag="PC592_003564"
     CDS             652..>2888
                     /locus_tag="PC592_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF4057484.1"
                     /translation="MKCLFSKIDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGIRIFIDDIELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKRFEARVTRFLSISVKELAVIKYSIKALN
                     SNAKIKFVPYLDSNIKNEDSNYEEKFWNGISSNSLEYKGSILSQTKENAFNTPVFTVG
                     SMMYIKTNGEVGAISHESNYNYCENSITMDALKNEVASIEKYVSITSTRDYKENELLR
                     KCEDILNRELSKNYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     ENAKKLGLKGALYPMVTFDGAECHNEWEITFEEIHRNGSIIYAIYNYTNYTGDYKYIK
                     EKGIDVVIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNVNNNWYTNYIAKWCLDY
                     AVENILRLEKEYNECIDRNNVTREEIDFWKIISKKMYLPYDEELQIIIQNDNFLDKEF
                     IEVKDLPKENLPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWDETLSFAPKLPKEWKSYSFNINYRDNIINVDVCSDLIKIENLKGK
                     AIKIIV"
BASE COUNT         1190 a          273 c          541 g          884 t
ORIGIN      
        1 agatggtgta attacagaca ctgcatatta tcactatatg gcttggaaaa aactagcaca
       61 taagattggt ataaatatag atacaaaatt taatgaatct ttaaaaggca taagtaggat
      121 ggaatcatta gatagaatat tggaatttgg aaacaaaaaa gatttatttt caaaagaaga
      181 aaaattgaaa atgtcagaag aaaaaaataa ttattatata gcattaataa atgatataac
      241 ttcgagtgat attttgccag ggatagaaag cttgttaatt gatgtaaaat ctaataatat
      301 aaagatagga ctatcttctg caagtaagaa tgcaataaat gtattaaatc atttgggtat
      361 aagtgataaa tttgatttta tagctaatgc agcaaaatgt aaaaacaata aaccacatcc
      421 agatatattt cttatgtcag cgaaagggct taatgtaaat ccaaaaaatt gtataggtat
      481 agaggatgca agtgcaggta tagacgctat aaactcagct aatatgtttt ctgttggtgt
      541 tggaaattat gagaacttaa aaaaagcaaa tttagttgta gattcaacaa atcaattaaa
      601 gtttgaatat atacaagaaa agtataatga gtatatggtt aggagaatta tatgaaatgt
      661 ttatttagta agatagatga gtggaagatt atacaagata agattgaaat caaagaaaat
      721 agattagcag agtccataat gagtataggt aatggatata tgggtatgag aggaaactat
      781 gaggaaaatt atagtggaga tacacacaag gggtcttata tagctggagt atggtttcca
      841 gataaaactc gtgttggatg gtggaaaaat ggatatccag aatactttgg taaaattcct
      901 aattcagtca actatatagg tataagaatt ttcatagatg atatagaatt agatttagca
      961 aaatgcaaag tagaagattt tcatagagaa ttagatatga aaaatggtat tttaaatcgt
     1021 aggtttattg taaatataaa tgataaaaga tttgaagcta gagttactag gtttttaagt
     1081 atatctgtta aggaactcgc agtaattaaa tacagtataa aagcattaaa ttctaatgct
     1141 aaaataaaat ttgtaccata tttggattca aatataaaaa atgaagattc aaactatgag
     1201 gaaaaatttt ggaatggaat ttcttcaaat tctttagaat ataaaggaag tattctttca
     1261 caaacaaagg agaatgcatt taatacacca gtattcactg tgggctcaat gatgtatatt
     1321 aagacaaatg gtgaggtagg agctatatct catgagagta attataatta ctgtgaaaat
     1381 tcaataacaa tggatgcttt gaaaaatgag gttgcaagta tagaaaaata tgtatctata
     1441 acttcaacta gagactataa ggaaaatgag ttattaagaa aatgtgaaga tattttaaat
     1501 agagaactat ctaaaaacta tgatgatata ttaaatgaac atacaaagtt atggaataaa
     1561 agatgggaaa gtgcagatgt aaaaataaat ggagataaaa gtagccaaca aggtataagg
     1621 tataatttat tccaattatt ttcaacatat tatggagaag attcgcgatt aaatataggt
     1681 ccaaagggat ttactggcga aaagtatgga ggagctactt attgggatac agaagcattt
     1741 tgtgttccag tatatctagg tgtagcagat aaggaggtaa ctagaaatct tttagaatat
     1801 aggtacaatc agttagaaca ggcaaaggag aatgcaaaaa aactaggact taaaggtgct
     1861 ttatatccaa tggttacatt tgatggagca gaatgtcata atgaatggga gataacattt
     1921 gaagaaatac accgaaatgg aagtataata tatgcaatat ataactatac aaattataca
     1981 ggtgactata aatatataaa agaaaaggga atagatgtag taatagaaat agctagattt
     2041 tgggcaagta gagttcattt gtctacaaaa aaagatttgt atatgataca tggagttaca
     2101 ggcccgaatg agtatgaaaa caatgtcaat aataattggt atactaacta tatagctaaa
     2161 tggtgtttag attatgctgt agaaaatatc ttacgattag aaaaagagta taatgagtgt
     2221 attgacagaa acaatgtgac tagggaagaa attgattttt ggaaaataat atcaaagaaa
     2281 atgtatctgc catatgatga agaattacaa ataataattc aaaacgataa ttttttagat
     2341 aaagaattta tagaagtaaa ggatttacca aaagaaaatc ttccccttaa tcaaaattgg
     2401 tcttgggata agattcttag gtcgtgtttt ataaaacaag cagatgtatt acagggaatt
     2461 tactattttg gaaatagatt tactaaagaa gagaaaaaga gaaattttga cttctatgaa
     2521 aaatatactg ttcatgaatc ttctttatct tctagtatct attctattat tgcctctgaa
     2581 atagataact tagaaaaggc ttatgagtta tactcaagaa cagctaggct tgatttagat
     2641 aattacaata atgatacaaa tgatggactg cacataactt caatgtctgg ctcatggctt
     2701 tctattgtac atggatttgc aggtatgaga acgtgggatg aaacgctatc ttttgcccct
     2761 aagttgccaa aagagtggaa aagttattct ttcaatataa attatagaga taatattatt
     2821 aatgtagatg tatgtagtga tttaattaaa atagaaaatt taaaaggtaa agcaataaag
     2881 attattgt
//
LOCUS       DAMKOJ010000179         2801 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000179 DAMKOJ010000000
VERSION     DAMKOJ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.188"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            118..873
                     /locus_tag="PC592_003565"
     CDS             118..873
                     /locus_tag="PC592_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4057485.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDNTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKEDLTVEEILEKFEYAV"
     gene            969..2006
                     /locus_tag="PC592_003566"
     CDS             969..2006
                     /locus_tag="PC592_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4057486.1"
                     /translation="MIKSKKILSLIIAGVLGISMLTGCSKNDGSNASNENKKTDIKNQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     ITSDENAKSAK"
BASE COUNT         1108 a          361 c          411 g          921 t
ORIGIN      
        1 taataactgc catagttata atagctttct tagctactgg taacttaaat atttcactaa
       61 aaaaaaacaa atgcaaaact agtaccaaaa ataaatcaga aaaaagaggt gttatagatg
      121 ttacaaatta aaaatctttc aaagagtttc cctaatccat acggtgaacc taatactata
      181 tttgaaaatt tatcaatcga tatagaagat ggtgaatttg taagtatcat aggtagtaat
      241 ggaactggta aatctacttt attaaatata atctctggac ttataaaaga atcttctggt
      301 caaattactt tagataatac cactataaca aatttagctg agtataaaag aactcaaata
      361 gtaagtagag tttttcaaga cccaagcctt ggaacttgtc cttctatgac ggttagagaa
      421 aatctatctt tagcacttaa taaagggaaa ttattaaact taaagaaatg tcttcgtcat
      481 aaaacgaatg atttggaaca cttacttgaa ggaatttctt tggacttaaa aaaatactta
      541 gatattaaag tacaatatct ttcaggaggt caaaggcaat cactctcact aattatgtct
      601 agtttagcaa gtcctaaggt cttattgcta gatgaacata cagcagcact tgacccaaaa
      661 acatcaaatg aagtaataga gttaacagat aaaatcgtaa gagaaaaaaa tataactaca
      721 cttatggtta ctcacaactt aaaacatgct cttcaatatg gtgatagatt gataatgctt
      781 cataaaggtg aagttgtctt ggatgtaaaa gataaagaaa aagaagattt aacagttgaa
      841 gaaatcttag aaaagtttga atatgcagta taagaaatta aaatcttagt tttaatcagg
      901 aatatttata atctattata tgaatatatg aacaaatata attattaaat tttgagggag
      961 gaaataaaat gataaaaagt aaaaaaatat taagtttaat tatagcaggg gtacttggta
     1021 tatcaatgct tactggatgt tccaaaaatg atggctctaa tgcctcaaat gaaaataaaa
     1081 aaacagatat caagaatcaa aaaaatatag gtattagtca attggtagaa catccatctt
     1141 tagataaagc taaaaaagga ttcatcaaag cactcgaaga taaaggctat aaagacggag
     1201 ataatataaa aatagatttc caaaatgcac aaaatgatat gcctactaca caaagtattg
     1261 ctagtaagtt tgcatccgac aaaaaagatt tgatatatgc tatatctact ccatctgcac
     1321 aggcagctta taatgctact aaagatatcc cgataataat gactgctgtt acagaccctg
     1381 tagaagctgg acttgttaaa tctcttgaaa aaccaggtgg gaatgtttct gggacatctg
     1441 actatctttc aattgataaa acattagaat tagttaaaac attgactcca aaagcaaaga
     1501 aaataggagt tatatacaat actagtgaag ttaattcaaa aatccaagtt gattctctac
     1561 atgattatgc taagaaaaat aattatgaag tagttgaaaa aggaatcagt tcttcaagtg
     1621 aagttaacca agctatttct agtttagttg gcaagataga tgttttatat gtacctactg
     1681 acaatttaat agtttcttct atgccaatag tttctaaagt tgctaatgaa aacaagattc
     1741 ctataatagc ctctgaagaa ggttctgtat cttctggtgc tttagcttgt tgtggaatag
     1801 attatgaaaa actaggttat aaggctggag aacttgctat tgaagtatta gaaggaaaat
     1861 ctgttggcga tatacctgtt actacattag atgaaactga aataataatt aacgaagata
     1921 cactaaaagc acttgacatg caaaagttat cagcagataa tataaagtat ataacgtcag
     1981 atgaaaatgc aaaatctgca aaataaaact tattaatgtc aaaaaatatg taatatgaag
     2041 taggtaatat gaaaacttta tataataagt actcttatcc accctaaccc tttgaaaatt
     2101 gtgcttattt tagcaatttg aatattgcat ataaagttat tcattttcca taaaagtcgt
     2161 ctatattgac gactgattat gaaagttata taactttcta atcactactt gagctgtcca
     2221 aaagaatttt aatattctct agacagcttt tttttatgag atttgattga tatatatgtc
     2281 tagttattcc atacttagta aatattttga taaaatttcc acatccacca caacttagga
     2341 taacgttttt tccaaataat atattaattt aaaagtattc taagtatata ttatttagta
     2401 ttttaattaa atttagcagt tgacttttat tattgtataa tttataattt ataacaagtc
     2461 gaaaatacat ataattttct gactaattaa aatattaaaa gggagagata attatgaata
     2521 ctttattaaa caataaaaaa tattattatt attatagcca ctatttttag ggtttgtacc
     2581 tacgttttaa catagataca gaccccttaa gactactaaa attttgggat tgtatctatg
     2641 ttggctatat tgtttataaa gttttcatgt aactatataa gagccacata gattaaacta
     2701 tgtggcttat tcgtgttttt accacatagt tttgtacact atgtggtttt tttatacaca
     2761 aaattagcaa ataattaaaa ttataaaaat attttcaaag g
//
LOCUS       DAMKOJ010000180         2578 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000180 DAMKOJ010000000
VERSION     DAMKOJ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2578
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.190"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(225..1475)
                     /locus_tag="PC592_003567"
     CDS             complement(225..1475)
                     /locus_tag="PC592_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HDF4057487.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMNNNEPLYDFITDDKIEHTVWKIDNDDIICNLVDEFRKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLCDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1507..2448)
                     /locus_tag="PC592_003568"
     CDS             complement(1507..2448)
                     /locus_tag="PC592_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF4057488.1"
                     /translation="MYNILVTDGIEKEAAKKLRELNFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLEKADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
BASE COUNT          779 a          493 c          235 g         1071 t
ORIGIN      
        1 aatacacatt taaaaccttc caaatatata aatacaatta tataaatttt catcctcaat
       61 tataacatag aatatgacta tctatatgct aaaattatcc attttcaaat aaaggtaact
      121 attattaaaa atatcaactt ataggattta tatcccatat acgattttca atcaaaaaaa
      181 caagggctaa aaagtgaatt gtacactttt tagcccttta ttaattattc atttatttca
      241 tgtaagaata gcccacatct tactttaggt tcaaaccatg ttgatttagc tggcattatc
      301 ttatttgcat ctgctactct tattaaatct tcaatactag taggatacat tgcaaatgct
      361 actttcatat cttcattaac tcttttttct aattcttcaa gacctctaat cccaccaatg
      421 aaatcaattc ttttatctac tctaggattg tcaattccta aaatagcatc aataacatag
      481 tcttgtaata tagaaatatc taatgagtca acagggtctt ctatttctaa taaattttta
      541 tttgctttca ttttatacca cttatcacat aggtacattc cgaaagttcc ttttttgtca
      601 ggtttatatt tttcttttcc ttctatttct tctagttcaa aattttcttt tattttattt
      661 ataaattctt cctcgcttaa accatttaag tctttgataa ccctattata atccaaaacc
      721 attaaatttt catctggagc aatcattgct ataaagtaat taaattcttc ttttccagta
      781 taatttggat ttttagctct catttctttg gctacatttt ctgctgaagc tgtcctatga
      841 tgaccatctg caatgtatag ataatctaat tttctaaatt catctactag gttacatatt
      901 atatcatcat tatcaatctt ccatactgta tgctctatct tgtcatctgt tataaaatca
      961 tataaaggtt cattattatt cataaaatca ttgattatat catctatcac cctttgatgt
     1021 ttataagtta caagtatagt tcccgtatta gcatcacagt attttatgtg tttagttcta
     1081 tcaatttcct tttctggtcg agtgtactca tgttttttta ttgttccatt caagctttca
     1141 tcaactgata tacatgctac tataccaact tgagctctac catccatgat ttgtttatat
     1201 atatatatac actctttatc atcttttact agaatttctt gttttcgaaa ctcatctaaa
     1261 ttttctcgcg cttttaaata aactttttca tcatataaat ctatattttc atctaaatca
     1321 atctctgatt tatctatatg caaaaatgaa tatggattcc cttctgcaat tcttctagct
     1381 tctttactat tcataacatc gtaaggaagt gctgctactt tatctactat atatttattt
     1441 ggtctaatcg ccttaaatgg tttaatcgtt gccattacta atttcctcct aattatacaa
     1501 aatattttat aatgctaccc ctattagatt gttgaagtca agaaagaaat cttgaatcac
     1561 atttactatt tcgtctccta ttctttcttg agcttctact gtagatgccc caatatgagg
     1621 tgtaggagaa actcttggat gatttactaa gtctagattt aatgtaggtt cttgttcata
     1681 aacatctata gcagcagctg ataatttacc ttcatctaat gcttttagta aatctttttc
     1741 atcaactaaa ccacctcttg cacagtttat taaataagcc cctttcttca tcttatttat
     1801 ttctttttca gttattactg cccccttatt cttatcaaat ggtatgtgta aagataagaa
     1861 atctgccttt tctaaaactt cttccatatc acagaattta taattgttaa agccttgcgc
     1921 ttcacccatt atgtcagtat atataacatt catacctaat aattctgctc tctttgcaac
     1981 ttcttttgca atccttccaa aacctataag tccaagtgtc tttccattaa tttctgtacc
     2041 tttatatttt ttcttctccc attttccatc tctcatagtt acatttgcag tatttatgaa
     2101 tcttgcaaga acaaataatt gacctattgt aagctctgca acagatatac tgcttgcatt
     2161 tggagtattc ataactttta tgccattagc ttgagcatat ttaacgtcta tattatctag
     2221 tcctactcct cctcttacta tcaacttcaa ctttttaccc tctaatgctt tatctattac
     2281 atctttagta accttagtag ctgaacgtac tacaagtaca tcaacatctt taagtttatc
     2341 tcctaaaaca tctttttcat aaaactgctc tatcacatta aaatttaact ctctcaattt
     2401 tttcgctgct tctttctcta ttccatcagt aactaatata ttatacataa caaactcctc
     2461 caatttttat tcacttaatt tttccaattt ttattttttt aagtattttc atcaataaaa
     2521 cactttactt aatttaactt tctgtttata taattttcaa aatatttttt tattaaaa
//
LOCUS       DAMKOJ010000181         2514 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000181 DAMKOJ010000000
VERSION     DAMKOJ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2514
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.191"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(84..782)
                     /locus_tag="PC592_003569"
     CDS             complement(84..782)
                     /locus_tag="PC592_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4057489.1"
                     /translation="MEKKYFKIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPQECQVLSVDLPEHGERKGEKNSFDPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPIIQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIMEDGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            1040..1597
                     /locus_tag="PC592_003570"
     CDS             1040..1597
                     /locus_tag="PC592_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4057490.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAENLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNNQMTKAVIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLM
                     SKEEAIKGLTDSIDTVLLGIHKKYD"
     gene            complement(1978..2451)
                     /locus_tag="PC592_003571"
     CDS             complement(1978..2451)
                     /locus_tag="PC592_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4057491.1"
                     /translation="MFNEHLIRELKEDDIKDALELIWNVFEEFESPDYCDEGIMTFHQ
                     FIEYNSIIEKVKEKTLFFWGCFDCEKLIGVLAIRDLNHICMLFVDKNYHKRGVAKKLM
                     TIGIEYCICNKFSLTEITVNSSPYAVEVYHKLGFKDTAVEQISDGIRFTPMKLLI"
BASE COUNT          954 a          332 c          317 g          911 t
ORIGIN      
        1 actaatttgt tctttatgta gttattttaa taatactaaa ataaaattaa ttaaataaca
       61 tttataaata atttaattat tttttattta actaaagtat ttaaccattc atataatgaa
      121 tttaattctt ggggtgtgtt aaaccaatgt ttgccatctt ccataatagt aaggttgcaa
      181 ttaaactttt ctacaaattt ctctacaaca ccaatttcag taagctcatc atgtttacca
      241 tataatattt ttgttggtac attccattgg atgataggat gttgttttac atattgtaga
      301 tattcccatg aaagagtatg cccaaatgaa gttgggataa ttagttcatg tttaagctgt
      361 tcttctgata catttgccca aagcatcata tttgaaataa gctgttgcat atctagaatt
      421 ggagatacaa aaatacactc tcttaagttc tctttttcaa agcttaacat actaaaccat
      481 gctccaatgc tatttgcata taacgaaatt tgattccagt ggcactttgc atattccata
      541 atagatacta gttctggaac aacatgccat gggtcaaatg aatttttttc tcctttacgc
      601 tctccatgtt caggtaaatc aacacttaaa acttgacact cctgtgggac tgcaatatta
      661 gcaaaagctt cagcctcctc tttattgcca cattgtccat gtatgtaaat atataattta
      721 cttgaaggat ttccccaaag aattgaagga actccatgaa ttttgaaata ttttttttcc
      781 ataaaaatct cctctcagtt tgatatatta gtgattgtta aattaatcaa actataaaat
      841 aatgttgtaa tatataattt aatataatac taattatatt agtattaaag ctaatttaat
      901 tagtattata ttaaattata attaaactgt caagatttta taatagtata aagaatttta
      961 taaattacaa taattgacga aactaattag attagttaaa ctaataaagt aattaatttt
     1021 aaatgaaaga gggaaaatca tgcgtgttag tagagaaata gttatacaag ctacatcaga
     1081 tatagttaat aaagatgggc ttaacaaggt ttctttaaaa gttattgcag aaaatctagg
     1141 aatacgtaca ccatctttgt acaatcatat agaaagtcta gatgatttat tacttgaagt
     1201 agctcataaa ggaatgagag agatgaataa tcaaatgaca aaggcagtta ttggaaattt
     1261 tggagataca gctataaagt gtataagtat agcatatttt aattttataa tttctaatcc
     1321 tggtgtttat gaaacaattc agtgggctac ttggcatgga aataatgaaa cattagaaat
     1381 ctttgatgaa tataaatcct tattagaaaa acttattctt tcttgcaatc taaatacaaa
     1441 gaatacaggt gaagtattaa acttaataat gagtgtactt catggttatt cgactttgca
     1501 acttgggaaa tcacttatga gtaaagaaga agctataaaa ggtttaactg attctattga
     1561 tactgtatta ttaggtattc ataaaaaata cgattaagta ggtaaatcaa ctattttaac
     1621 acatttattg aacaaatttt catgaggcat ataaattata attccatgat aaaaaatttt
     1681 accatttgta acaaaggaaa agctacagga tagaagtata ttgcaataat gtttattttt
     1741 taatggacaa tcattcttac aaataggaga tatatatgga aacaacataa gttaagctta
     1801 ataattgaat tgatttatat attagtcaaa aaaatatcaa aaaataaatc agagttccat
     1861 attagtaagg cttttaaggt atgttataaa aaaaataaaa aagatagtgc tatttttaaa
     1921 atttaattta aaagcaaagt caccataaag cattcaagag actttgcttt ttatttacta
     1981 tattaacaat ttcataggtg taaaacgtat accatcagaa atttgctcaa ctgcagtatc
     2041 tttaaaccct aatttgtgat agacctcaac agcataaggt gatgaattta cagttatttc
     2101 agttaaacta aatttattac aaatacagta ttctatgcct atagtcatta atttttttgc
     2161 aacaccacgt ttatgatagt ttttatctac aaataacata catatatgat ttaaatctct
     2221 aatagctaag acaccaatca gtttttcaca gtcgaaacaa ccccaaaaga atagtgtttt
     2281 ttctttcact ttttcaataa tagaattata ttctataaat tgatgaaatg tcatgattcc
     2341 ttcatcacaa taatctggag attcaaattc ttcaaataca ttccagatta attctaatgc
     2401 atctttaata tcatcttctt ttaattctct tattaagtgt tcattgaaca ttataaacaa
     2461 cacctctatt attaaaaatt ttaattataa ttataattat ataccttaaa taaa
//
LOCUS       DAMKOJ010000182         2509 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000182 DAMKOJ010000000
VERSION     DAMKOJ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.192"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            144..953
                     /locus_tag="PC592_003572"
     CDS             144..953
                     /locus_tag="PC592_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF4057492.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELNLIDKKVAELISHKEN
                     IIKRLSSIESAVKNTKIDEIEVIYIKKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKVYMEKVFEFIEENNYKVIADPIEIYKIDIHETGIVEEFITEIQVPIIK"
     gene            complement(1062..1271)
                     /locus_tag="PC592_003573"
     CDS             complement(1062..1271)
                     /locus_tag="PC592_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057493.1"
                     /translation="MGNNDKEKSKNSKNIFHDIPVLVNNFFWSMIGFIVIKNFGNGNF
                     FTYLLGIGAGLLWGIFIQKFFTNNK"
     gene            complement(1757..2431)
                     /locus_tag="PC592_003574"
     CDS             complement(1757..2431)
                     /locus_tag="PC592_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF4057494.1"
                     /translation="MNHYILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     KADSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
BASE COUNT          968 a          292 c          342 g          907 t
ORIGIN      
        1 atattttaat aattaattgt aggatgttta ttttcctatc cttgttttag agattttttt
       61 agtatattct aatactatag tattatagag taataatgtt aatttaaaat aaaaataggg
      121 ttatggagga gtttattata taaatgaaag attactataa aataggagag atatctaaaa
      181 tatatggaat aggcagagat tcattaatgt attatgagga aatagggatt ctaagaccag
      241 ttagagatat aaatgggtat agaatgtata atatatcaga catatggaaa ctaaatttaa
      301 taaaagaatt tagaagtttg aactttccaa tgaaaaaaat aaaagaatat ttagatgata
      361 gaagtataga gtctacgaaa aacatcttaa atgaggagct taatttaatt gataaaaaag
      421 tagctgaact tataagtcat aaggaaaata ttataaaaag attaagttcg attgaaagtg
      481 cagttaaaaa tacaaaaata gatgagatag aggtcatata tataaaaaaa agaaaagctt
      541 tagaattaaa tgctgatata aagagagatg aagattttga ctttttaatt caaaagcttc
      601 agaaagaata tgaagataga tttaatatac ttggaaacaa caatattggt tctgcttttt
      661 ctactgaagc aattaataaa ggtatattta atgaatttaa atctgtgttt tgttttctgg
      721 aaagtaatga gaaagtatac aatatagttt ttgatgaagg gtattatgtg actttaaatt
      781 atactggaag taattctaac aataaggtat atatggagaa ggtatttgaa tttatagaag
      841 aaaataatta taaagtaatt gctgacccta tagaaatata caagatagat atacatgaaa
      901 ctggaattgt agaggagttt ataactgaaa ttcaagttcc tataattaaa tagctagatt
      961 tcaacaaatt agatgataaa tagtataaaa aaatgagttt accactatat tataaaagta
     1021 gtggtacatt ttttatttgg gattttttgt ttaagatgtg tttacttatt attagtaaaa
     1081 aatttttgta taaatattcc ccacaataaa cctgctccaa tacctaataa ataagtaaag
     1141 aagtttccat tcccaaaatt ttttataaca ataaatccta tcattgacca aaaaaaattg
     1201 tttaccaata ctgggatgtc atgaaatatg tttttactat tttttgattt ttctttgtca
     1261 ttattaccca taatgtcatc tccttaccat aagcattgaa cactgtgcat tacctagaaa
     1321 tcattgaaat atttaaacta attttttagc ataagattat ttataaatta gattaaaata
     1381 aaaaggatat acgtttttac aactagataa aataactcat aatatatttt ataaatatca
     1441 gtacatatag ctttatatca ttaaagttct ctagttttga tgatttagtt taattttata
     1501 gtttaatagt acaatagaat tatttattgt tcaacatatg tattttaaag ttgaaaaaat
     1561 ttatagatat gaagactatt gtacaactaa aaatgcacta gatgtctaga actatggcaa
     1621 ctatactgta gttttttaat aaaatatata tgtgaattga taaaaataag ggacgaactt
     1681 tatatagaat catcccttga tatctgcatt tttattttaa ttaaatatat tattatcttt
     1741 aaagttctat tttacattat atttctaatg tttctataag aggattatcg ctaaataatt
     1801 ttaataaatt tgtttttttg tatcctttag gtaacttagt atatataact acctctaacc
     1861 aatctccatc aagacgttta atattcatgt ttataatttc aatattagat tttttaaatt
     1921 taccttcaat atattctata gaatcagctt tattagaaat cttaagagaa acttgttctg
     1981 ctgtagggag tttcatccat ttcctatctc tatgaagtgt tatctgtaca ataacaataa
     2041 tgatacttga aacaatacca actaagtata atccagagcc aatggcaaga cctgtaccgg
     2101 ctgttgccca tataccagca gctgtagtaa gaccacttac tgattgattt ctaataaata
     2161 ttaatccagc acctaaaaaa cctatcccac tgacaacttg tgctgcaacg cgggctgggt
     2221 ctagaccaat acctggagta cccactatat cattaaatcc atacttggaa acaatgatta
     2281 taagtgctga agctaatgcc actataaaat gagtgcgtat tccagcttct tttagtctat
     2341 tctttctctc atatccaatt aaagctccac agaaaccagc agtaatgatt cttgctatgt
     2401 attcaaattg aatcaatata taatggttca tttgtctagc acccctttct atataatatt
     2461 atatatacta taatactaca ttttttatgt gaatatagta aagtttaaa
//
LOCUS       DAMKOJ010000183         2499 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000183 DAMKOJ010000000
VERSION     DAMKOJ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2499
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.193"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            79..1926
                     /locus_tag="PC592_003575"
     CDS             79..1926
                     /locus_tag="PC592_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF4057495.1"
                     /translation="MTKRVLSNFTLTGKNILSKFIFMIRYNFSTLILFELFYKGLALL
                     LILPSIKYIFDNLLKSLNIFYLNMDNIIKILSNPISIVLIILSVIILAFYAFFEFTSV
                     IICFNRSIKCEKIGLFELIKMSFKKSINLLYPKNILLFIFVLLIIPLVNTVLISGFIG
                     KIQIPDYILDYIKSNNILNIVYMISLFIIYILVIRWIFSVHEITLNTENFKIARKESV
                     NLIKGRIIRTVIYSLILSLVMAIIGYVIYHIGIISIGIWTKYYTNIGSLKELFINRCI
                     SFEDYFSLILSIFIFIVDIAFISATYYEYKGVNISRNNIIKEKKSIPKTIFKLSLIIL
                     IFCVESNAYSSHVNGLFNTSFSFNTTTIAHRAGAERAPENTLIALKEALNAKADYAEI
                     DVQETKDGELIILHDSNFKRTTRVDKNVWDVNYDEVRTYDAGSFYYDGKGYYDERFVG
                     EKIPTLDEMIKYSKGRIKLLIEIKLTGHEKGDVTKKVVQLIKENNFENQCIIASMDKT
                     VLQKVKKLDKNLMTCYFMAVAYGDFSKLNYIDVYGIESTFVNTTVVEKIHKMNKKIFV
                     WTVNSYSLIEKMLDLNVDSIITDNPYLVDGAIVWKKNGFINKVSDYLFS"
BASE COUNT         1001 a          225 c          326 g          947 t
ORIGIN      
        1 ggaataatat atactaatat tctatataca tttaaaatat tgtataaaaa tacaataaac
       61 agatacaagg aggtaaatat gacaaagaga gtattaagta atttcacact cacaggaaaa
      121 aatatcttaa gtaaattcat ttttatgata agatataatt ttagtacatt aattttattt
      181 gaattatttt ataaaggatt ggccttactt cttatactac catctattaa atatatattt
      241 gataatttac taaaaagttt aaatatattt tatctaaata tggacaatat tataaaaatt
      301 ttgagtaatc caatatctat agttctgatt atattatcag ttataatatt agctttttat
      361 gccttttttg aatttacttc tgtaattatt tgctttaata ggtcaataaa atgtgaaaaa
      421 ataggtttat ttgaacttat taaaatgtca tttaagaaat ctataaattt attatatcct
      481 aaaaatatac tattatttat atttgtgtta ttaataattc cattagtaaa tacagtttta
      541 atttcaggtt ttataggaaa aatacaaata ccagattaca tactagacta tataaagtct
      601 aataatattt taaatatagt ttatatgatt tctcttttta ttatatatat tttagttatc
      661 agatggattt ttagtgttca tgaaataact ttgaatacag aaaattttaa aatagcaaga
      721 aaagaaagtg ttaatcttat aaaaggaagg attataagaa cagttattta ttcattaata
      781 ttatctttag taatggctat tattgggtat gtgatttatc atattggaat tatatctata
      841 ggcatatgga ctaaatacta tactaatata ggatctttga aagaattgtt tataaataga
      901 tgtatttcat ttgaagacta ttttagtttg attttatcaa tatttatttt tatagtggat
      961 attgcattta tctcagcaac ttattatgaa tataaaggag taaatatttc taggaataat
     1021 attataaaag agaaaaaatc cataccaaaa actattttta aattatcact aataatatta
     1081 attttttgtg tagagtcaaa tgcatattct tcacatgtga atggtctgtt taatacatca
     1141 ttttccttta atacaacaac tattgctcat agagcaggag ctgaaagggc tccagagaat
     1201 actttaatag cactaaaaga agctttaaat gctaaagctg attatgcaga aatagatgtt
     1261 caagaaacta aagatggaga gcttattata cttcatgatt cgaattttaa gaggactaca
     1321 agagtagaca aaaatgtttg ggatgtaaat tatgatgaag taagaacata tgatgcagga
     1381 agtttttatt atgatggaaa aggatattat gatgaaagat ttgttggaga gaaaatacca
     1441 acccttgatg aaatgataaa atattctaag ggtaggataa aattactaat agaaataaaa
     1501 cttactggcc atgaaaaagg agatgtaaca aaaaaagttg tacaattaat taaagaaaac
     1561 aattttgaaa atcaatgtat aattgcatct atggataaaa ctgtattaca aaaagtaaaa
     1621 aaactagata aaaacttgat gacatgctat tttatggcag ttgcatatgg tgatttttca
     1681 aaattgaatt atattgatgt atatggaatt gaatcaactt ttgttaatac aacagtagta
     1741 gaaaagattc acaaaatgaa caaaaaaatc ttcgtttgga ctgtcaatag ttatagttta
     1801 attgagaaaa tgcttgacct aaatgtagat agtataatta cagataatcc atatcttgta
     1861 gatggtgcaa ttgtttggaa gaaaaatgga tttattaata aagtatcaga ttatttattt
     1921 tcttaatgtt taccatatct aataaaaaag agatattatt aaaagtacta atatctcttt
     1981 ttttattaaa aataaaagca attattaata taagtgtatt ttattctacg atagtgtgaa
     2041 agtatacaaa caataataat attattgtat tgatataaat aattgtaatt gcgttgtttt
     2101 atctaacaag tgtatattct atatagatag gatatttttc aaggtttcat atccatattt
     2161 atctactaag tctttatgaa atgtagtttt tattacttct atcttacatt ttttcatgaa
     2221 agctatctcc tcatatattt atataagtat atgttctatt ttaagtttaa acaagtacct
     2281 acttttaagt aaagtactaa catttaggaa agttatttcg ttataatata gagattaaat
     2341 aagaatgaaa aattataaca tagaaggttt taataaatat aatttttctc ctatttaaat
     2401 atgttgtttt gattataaac atcattgaga taatacactt aattaataat ataaaagagg
     2461 ataaaaattt taaaagttta atttttggct aaattaaca
//
LOCUS       DAMKOJ010000184         2328 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000184 DAMKOJ010000000
VERSION     DAMKOJ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2328
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.194"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            111..1709
                     /locus_tag="PC592_003576"
     CDS             111..1709
                     /locus_tag="PC592_003576"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF4057496.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDVKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VISVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEVMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLVLAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1800..2012)
                     /locus_tag="PC592_003577"
                     /pseudo
     CDS             complement(1800..2012)
                     /locus_tag="PC592_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888191.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
BASE COUNT          884 a          296 c          343 g          805 t
ORIGIN      
        1 ataatatttt ttcactaaat ttttttcttt ttacaacaaa tactcactac cttttgatat
       61 aatattttta tcaattatta ttatattcaa gttttgaaag gagtattaaa atgagtttat
      121 tagttttcgg acataaaaat ccagacacag attcaatatg ttctgcaatt tcattagcac
      181 atttaaagaa caaactagga ataaaagcaa cagcttatgc tttaggagat atcagaaaag
      241 aagctaaata tgccttggat tactttaagg tagatgcacc tgaaatttta gataatgtta
      301 ggatacaagt tagagattta aattatgaca aagtagtacc tttaacacca acttcatcta
      361 tattagaagc ctataacctt atggatgaaa aaaatgttaa aacactacct gtaacttatg
      421 atgatggaac ttttgctggt atcattacta tgaaagaaat agctaaaaac ctacttcatc
      481 aacactttac aactatacac acatcactat caaacatttg taaaaacctt aatggtacta
      541 ttcttgtgga ttgtggtgaa gatgtaaaag gtagagtagt tactttatca tttggaatgg
      601 agactctaat agagacttta aaagagggag atatagctat tgttggcgat agatatgata
      661 gtattgaata tgctattgat acaaaagtta aacttttaat acttactaat catacagaga
      721 tttcaaaaga cttgctagct cttgctaaga taaatggagt gtctgttatt tctgttgaaa
      781 gtgacaatta taaaacttct aatgtaataa atcaatgtag tttcttagac tctatagaag
      841 ctacagaaaa tttaattaca ttcaaagaag atgattatat ggatgaaata aaagaggtta
      901 tgctagagac aaacttcaga tcttatccaa tattagatga tgataataag tttttaggtt
      961 tagtttcaaa aggtcatcta ttaaacccat ctaaaaagaa tgttgtttta gttgaccata
     1021 acgaatatgc tcaaagtgct gatggaattg aacaagcaaa catagttgaa ataattgacc
     1081 atcataaact tggtggtatt tctactgatg ttcctatgtc atttagagtt atgcctgttg
     1141 gatgcaatag tactataatt tatcaaatgt acaaagaaaa taatgttgag ataccttatg
     1201 aaatagctgg gcttctttta tctgctatat tatcagatac attattattt aagtctccaa
     1261 caacaactga tatggataag aaggcttgtg aagaattaag taaaatagca aaagtagaca
     1321 tggaaaaata cgctatggat atgtttaaat gtggtacttc tttagatgaa tatactatag
     1381 aagaaatagt aaatatggat tttaaagagt ttaatatgag tggacataga gttggtattg
     1441 gacaggtatt tactttagat atagactcta tatttgctaa aaaagatgag tttttatctt
     1501 atataaattc gactgattat gataaattag ttcttgcagt tacagatata atcaaagaag
     1561 gttcttattt aatctataaa gcagaagata gcttaattgc taacgcattt ggtgttgaag
     1621 gggttcaagg tacatttgca ccaggtgttg tatcaagaaa aaaacaatta gttcctaatt
     1681 taactactgc aatcaaaaat tttaaataat ataaagtttt taaacaataa aaaagaaggt
     1741 gtctcaaagt gaattttata gtccatgagg cactcttttt tgtataaaat caaatatatt
     1801 attctaaata tcatcaaagt agccgtaatt accgctgatt gcccatttcg tattcctact
     1861 gctatagata aaaaattatt tatagtaaaa gtagttcctc caaataaaaa gccagcgaaa
     1921 tacccagaaa gtactcatca tcatgattca gtagtaagac ctgttaaatc tcttcctcct
     1981 agaattagaa ataaaatagc gaaagaatac atacttagtt gcaacataat taaaatttac
     2041 agtcttaaat ttttatatta ataatgctaa tttccacaaa aaaagaacat gtaattagaa
     2101 tcttctaaca gcatgttctt tttcattatt atatattaca ctttaaatta ttccttgact
     2161 ggcttagctg gtgtaaacta aaccagtctt tctaaaatat taagcacttt tttcttatta
     2221 tgttttttag gatttattgt ctatattatt gtaaaccaaa gttataaaat tgtaaataga
     2281 atatattacc atatcaatat ttttttataa gtaaaaatta taaaaaaa
//
LOCUS       DAMKOJ010000185         2270 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000185 DAMKOJ010000000
VERSION     DAMKOJ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.195"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(153..1445)
                     /gene="brnQ"
                     /locus_tag="PC592_003578"
     CDS             complement(153..1445)
                     /gene="brnQ"
                     /locus_tag="PC592_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF4057497.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFARAGKGLSVALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     DKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     VPLVNNLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          762 a          369 c          250 g          889 t
ORIGIN      
        1 aattgtacta ctccaaaact aaatttttca atttattaaa taggattaat aatagtcttt
       61 tatctacaat aatttaataa ttcttttaaa tataaaagga attgcctata taatttaaag
      121 gcaattccat aattatcaat tagtttttat aattatgcag ttttgctact tttagatgga
      181 ataaagtttc ctattattcc tgctattaca actggaacta tccagttaaa tcctaatgaa
      241 gcaaatggta agttattaac tagaggaact ttcacaccaa aacttgttgc aactgttaat
      301 acacttacta ataatgccat atatgcagca catttgaaca cgttatcatt tttaatttta
      361 ttactaaata atgctagtat aactagagtt atagttgctg gatataccat acttagtata
      421 ggagaagaga attgtattat tgtacttact ccaaagtttg atattattgc actaaataca
      481 caaactacta taactatatg ctcatatttt aattttccat ctgtaagtgt tgagaaatat
      541 tgaccagctg ctgaagaaag acctatagct gttgttaaac atgctaatgc aactataata
      601 gctaataaaa ttttacctgt agttccaagt aaagctgctg ttattgcaac tattaaagct
      661 gtttgttgaa catcttgtcc atattgttga gacacagttg ctccaagata acataatcca
      721 ccataaacta gtgccattcc tattactgca atcacacctg cacttattgt ggctttcatc
      781 ttttctttat cacctgtata acctttagct attactgaca tgattataat tgatgcaaat
      841 acactagctg ccaatgcatc cattgtttga taaccttgag ttataccttc tgcaaataca
      901 ttttgtatta aagaactgtc tcttatttct cctaatggag atacgatacc tttaactatt
      961 aatactgcta aagctataag taaagctgga gttaatattg acccaactat atctacaact
     1021 tttgatggtc ttattgttaa aaccaatact aaagcaaaga acactataga gaatatcact
     1081 ggacttattc cagaacctat tgtaggtaat atacccattt cataagttgt tgctgctgtt
     1141 ctaggtattg ctaaaagtgg ccctatacag attaccattg cacatcctaa tgcaacactt
     1201 aatcctttgc ctgctctggc gaacatcttt gatgtgtctc cattgaactt agttgctgct
     1261 ataactgcta ataatgccaa accaccatct gcaaaaagga atcctatgaa agctactagc
     1321 cagctacttc cagataaaac tcctaaatat ggagggaaga ttaagttccc tgcaccaaaa
     1381 aacattgcaa atagtgcaaa tccaattaca attacatctt taaaattgat ttgtttctca
     1441 cccatttaaa gcacccccat ttgaatttta ctacatttta ctaaaaaata agtccaatct
     1501 cttcttaaat gaaaaccttt tgacgagatt ttatttaatt atacattttt gacttaaatt
     1561 tgtcaattat gtttcataat ttataaaatc ttcacaatat ttaatacaac tttcttaatt
     1621 aaacaaaatc aacgtgtata ctttaaacat agttggtttt ttgtttttta tctaattttt
     1681 cttgataaaa ttaattattc tgaataatta aaatattagg attttttaga ttattcgttt
     1741 tattattaag ttgtattgct ttatgtatta tatatcactc tcctttttac atacatataa
     1801 tctttttaat tcaatttaaa ttttaaatat tttgtgttta ttatataatc tgaaaaaaaa
     1861 gcagtcaata gcatttttaa ttttttaaat tttcaaaatt atgatttttg aaaaatcgtt
     1921 ttccttttat catagcacct atttacgtta attcttgtag tattttgtat ttattttgct
     1981 aaatttatag ttaactttat ttaatttcta ttctacttat atagattcac ctcttgcttt
     2041 ttagttttga aatcgttttt tctgaaaatt ccttattatg atttatcaac ttatttttct
     2101 tcatagtaat tattttctaa cttccaactt acttaaactt tgcagttgct agtattcacg
     2161 tttacatact tatctgtcat aattaactaa aaattcttaa tatatctctc agtaaaaaca
     2221 attcaatcat ttacttaata catttatata atcatatgtc ttaaattttg
//
LOCUS       DAMKOJ010000186         2117 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000186 DAMKOJ010000000
VERSION     DAMKOJ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2117
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.196"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(755..1540)
                     /locus_tag="PC592_003579"
     CDS             complement(755..1540)
                     /locus_tag="PC592_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057498.1"
                     /translation="MKKQKIITSLLITGVLATNTYPVFASQAIQTQNLTSIEQRISSN
                     VLLKCDQSSINYTNFFKNGGGEQWVKLTLEGAKFNTNDPYEIKNAIKQNYDVQTTIAV
                     GTDGKSIEFGVYEPNAGIEYLPNWEININSSVLTSDTDATIKIPVNYDIHTSATPKII
                     TSKKSITLDELKNGFELDLEGIQGAQFNTDCVGNNVRLSLMHTANIPVMAMTYCDLDT
                     THIGFIIKALNDIPSTATEFTFRIEGNATTSQVPLLVKLPIVK"
     regulatory      complement(1895..1982)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT          729 a          235 c          309 g          844 t
ORIGIN      
        1 tttaataact attagaataa atatttattc cgaaaagatg ctttaaagta aattacattt
       61 ttatttataa taagagatgc aagtgtaatg ttttagatat aataattaca agtatatata
      121 aattatacta atggttttat agtagctaag tgtttatatg gtaataaaaa ttgtaattgt
      181 aatttatgat ggtgataata cataaatgag gttggcaatg ataagcttat gtagtttatt
      241 aaataaaaat tattaataat caattatcaa tgattatttt aacttatgct tttgcattat
      301 atgtgtaaat ataacaattg aagatatttg gtatttgaaa tttctagttt tatgagaaac
      361 ataatatcgc tcagataaat ttgttatgac attacaagaa tttttaaagg tatattgctt
      421 aaacttaaag gcaaagatat attgtcagat aaagcagtat ctattaaaga tgaaattttt
      481 attaaagagc aagtagaaac tgtcatatat cttcaaattt agtaagtatt attttgtgaa
      541 tatctttgcc tttattaatt tgtattgatt gtttttcaat taaatcttct attatagttg
      601 attatatgaa aaattctgta ttatttagta atcataatat agtttagttt ctctgcttat
      661 tgtataagtt tttaaagcag atgtaatgta gcttagttat agtcataggg ataacagtat
      721 tagcttttaa agtttatatt atatgtttaa agttttattt tacaatagga agcttcacta
      781 gtaatggtac ttgagaagtt gtagcatttc cttctattct gaatgtaaat tctgttgctg
      841 ttgaaggaat atcatttaaa gcttttatta tgaaaccaat gtgtgttgta tcaaggtcac
      901 agtatgtcat ggccattaca ggaatattag cagtatgcat taagctaagg cggacgttgt
      961 tacctacaca atctgtatta aattgagcac cttgtatacc ttcaagatct aattcgaagc
     1021 cattttttaa ttcatctaat gttatacttt ttttacttgt aataatttta ggtgtagctg
     1081 atgtatgaat atcatagttt acaggtattt taatagttgc atcagtatct gatgttagaa
     1141 cagaagaatt aatgttaatt tcccagtttg gtaagtattc aataccagca ttaggttcat
     1201 atactccaaa ttcaatggat tttccatctg tacctacagc tattgttgtt tgtacatcat
     1261 agttttgttt tattgcattt ttaatttcat atggatcatt tgtgttgaac tttgcacctt
     1321 caagggtaag ctttacccat tgttctccac caccattttt aaaaaagttc gtgtagttaa
     1381 ttgatgactg gtcgcattta agaagaacat ttgaagatat tcgttgttct attgaagtta
     1441 aattttgtgt ttggattgct tgagatgcaa acactgggta agtatttgta gctaatactc
     1501 ctgtaattag tagtgatgtg ataatttttt gctttttcat ttttgtttcc tcctataata
     1561 tgttatattt ttaacagtga aatgaaataa aatacaaggg caatataaaa tatatgtcgt
     1621 tttgaagtgt attaagattg tgtgaaatat tattagttat actgaaatat actagtctat
     1681 agatatacat agtttaaaat aagtaaagta gtattactgt cttacttaac actcgttttt
     1741 aatccataaa ataatgtttt cagagttaaa taattatctt tcaaatctaa tctcaattct
     1801 ttagcataga ggttatagat acaataataa gaatatggct agaacaaaaa aatacctcat
     1861 aaggaggtat tatctaacaa aaagtacact aacttttagt aactggcagg cataatcttt
     1921 ttaagacctt aacccctata gctttgcgtc cctagatttc tctaggtttg cctattaagt
     1981 tttgcgtttg catttttaat atcatatcaa tctgttttat agaatgataa cacaaataaa
     2041 acttataatc aacaattaca tgaaattttt ggaaaaaaat tatatattac aaaaataata
     2101 ttttcttcat gaataat
//
LOCUS       DAMKOJ010000187         2030 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000187 DAMKOJ010000000
VERSION     DAMKOJ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.197"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..240)
                     /locus_tag="PC592_003580"
     CDS             complement(<1..240)
                     /locus_tag="PC592_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057499.1"
                     /translation="MSNNLSNININENNLIKNQYSISLIKECFDCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYA"
     gene            complement(263..697)
                     /locus_tag="PC592_003581"
     CDS             complement(263..697)
                     /locus_tag="PC592_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057500.1"
                     /translation="MISPIILSSINRNLKEIERNKLFETNIESRDYGLTLSESDVKDI
                     INFRDNTLKGYGRIELDIKVTKQLIENIYISQYTNMDNYLETINDMQEIFYYLKNETD
                     DKICDDEIIEILDELYEKFSGNINNVRGEADEFVKKFKFGEV"
     gene            complement(957..1868)
                     /locus_tag="PC592_003582"
     CDS             complement(957..1868)
                     /locus_tag="PC592_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF4057501.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYRITEEDELYIVPTEDAVFSMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLDFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSADEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLIFSKFYTEQLDWIVSFAKDMYKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
BASE COUNT          657 a          337 c          162 g          874 t
ORIGIN      
        1 agcataccat atcgaaatca acaatttttc agcaacttct gtttttactg atgtgctttg
       61 accatttgta tattttttaa tcaaatccat aagtattagg gatatttctt gttgtatatt
      121 atatacttct ctttcatcta taactttaca atcaaaacat tccttaatta aagatatgga
      181 atactgattc tttattaaat tattttcgtt tatattaata ttacttagat tatttgacat
      241 atcaaatctc tcccatcata cattaaactt ctccaaattt aaatttcttt acaaattcat
      301 ctgcttctcc tcttacattg tttatattgc ctgaaaactt ttcataaagt tcatccagta
      361 tttctataat ctcatcatca catatcttat catcagtttc attttttaaa taataaaaaa
      421 tttcttgcat atcattaata gtctctaaat aattgtccat atttgtatac tgtgatatat
      481 atatattttc tattaactgt tttgtaactt ttatatctaa ttctattctt ccatacccct
      541 ttaaagtatt atctctaaaa tttattatat cttttacatc agattcagaa agagttagac
      601 cataatctct agattctata ttagtctcaa acagtttatt tctttctatt tcctttaaat
      661 tccgatttat agaactcaaa ataataggtg atatcatttt taaactctcc ttttttattt
      721 tttctattga ctttttttat tttttatgtt atatttaaat taatatacat tcttttagca
      781 actacttata atagtattat tgtaagtagt ttttgtcaac tcaaaattac tatctcaatt
      841 aaacttttcc attttctcaa taaaaaaata ccattattta gatatataat tttctataac
      901 aacttttaat tcagcagtta tttactaaaa tctaaacaat gatatattta ttaattttat
      961 ttatcttttt tagctctact tctacttttc tttacatttg aacaatttct acaagaaggt
     1021 gaacagtatt gagatttaga atttgtagga atataaattt taccacagta cttacattta
     1081 tttaaagaag aaggttcact tgtaattgca aaagcataga tagtctcaat cgctgttttc
     1141 aaagaatcaa actcccatgc aataattggt ttatctaatt gacttataga aaatcctatc
     1201 ttttggggat taaaccctcc agacataata gtaacacttt cagttaacag attagaggta
     1261 tttttatata cacaaatttg attaaagtgc ttatacatat ctttagcaaa gcttacaatc
     1321 caatctagtt gttcagtgta gaactttgaa aatattaaat ctaaaatcaa tggtctcttt
     1381 ccaaaaaact ttggagattc ttctctcttt gatacatcta tacctcttct atacttttta
     1441 aaatacacgt cttcatcact tgcaaatggt ataaacatgt ttacatattc atcagcactc
     1501 aatatatttt cttttgtaat ataattcttt tcaatcatca gtactctttc ttctccaact
     1561 atatctctat tatatacact tgagtatatt aaacccaata atccatattt ttttacaaag
     1621 tcaagtactt ctttctttaa tttcatttct ttcgtctctt ttgatatatc ttgtagtgcc
     1681 tcttgtccta tacgaattat atctactatt atatcatctg ctacatcaaa tgggttgtac
     1741 atgctaaaca cagcatcttc tgttggaact atatatagtt catcttcttc agtaattcta
     1801 tattcataat cactatacct aatccaatca cttgcaaaat tccctattaa ttctattttt
     1861 ttattcatga taatcattta cccctttcaa tgtaatatat aattttatat tactattaca
     1921 tttttagttt attccatatt ttctatactg tcaactattc ttttatattt ctgtaatatc
     1981 aaaatttata acaaccttta taatgaactt actaagctaa atttcttgtt
//
LOCUS       DAMKOJ010000188         1991 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000188 DAMKOJ010000000
VERSION     DAMKOJ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1991
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.198"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(451..1779)
                     /locus_tag="PC592_003583"
     CDS             complement(451..1779)
                     /locus_tag="PC592_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF4057502.1"
                     /translation="MESNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMIVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPASELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYSIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGIKR"
BASE COUNT          730 a          353 c          210 g          698 t
ORIGIN      
        1 tttgccacat ttttaataca tatattatat attcatattg tttaattttt gttatcaagt
       61 aaaattttct aatcttcctc ataaatcact atattaacca ggtaatattt tctatataat
      121 acaatattct attatataca acagaaagat ttaattttca taaaacctat atataatatt
      181 tgttatatag atatcattta gtttgataaa aaaatacttt aaaataaagt attttaaagc
      241 aaataatttt ttagatgttt aattttgtaa tccaaaaact aaaaataaaa taaatacctt
      301 aagataagct ttttagttca tgaaacactc tttttttata aaatcaaacc tatctttgtc
      361 attttaacaa taaaaaagag acttctctct attttgagac agtctctttt attttttaaa
      421 taattataaa gcatttgtaa actacttaat ttatcttttt attcctctag tcatataagc
      481 atacactggt aaacctatag ctgttattac aagtcctcct atagatatca tagtagtttt
      541 catacctgca aaacacaatt gattaactac aacaaatata ccacttgcta tagctattat
      601 cggaacaata ggatataatg gcactttata ctctcttggt atatttggat gagtctttct
      661 aagtttcatt acccctataa aagttaatac atagaatatc caagtagcaa atacagctaa
      721 gtcagttaat aaattaaatt gacctgacaa agcatatata gatgcaataa cagatactaa
      781 tgctattgca tttgctggaa cttgagcaga atttaattta gagaatatac tatattttgg
      841 taaagtctta tctgtagcta aagtgtatgc cacccttgaa ccagttagta aaaatccatt
      901 taatgctcca aacactgaaa ttaatatacc tacagatatt attttcccac ccattgaacc
      961 aaatataact tcagcaactg ctgatgcagg agaagcataa tttgctaatt cactagccgg
     1021 taatacccaa agatatgcta aatttattat aaagtaaaca gccataacaa ctgataatcc
     1081 acctattata gcttttggaa ggtcttttcc aggattcttc atttctccag ccaaagtacc
     1141 aacattcatc catccatcaa atgcaaataa tatagcaatt aaaacttgac ctaatacact
     1201 acctagactt aatccctcac caaccatagg cgtaagtatt ggattatttc caccaccttt
     1261 aataaatcca acaatcatta ttaaaataag tggtattaat ttacaaattg tagaaacagt
     1321 ttgtataact cctccagttt ttgaacccag catattaagc cctgcaacta ttactataat
     1381 tccaattgct attggaagta agagtgatgg actaccaatt agtgctgatg cttgttctcc
     1441 gaatataaca cctaatgctg ccatcatccc tggataaaat aatacaattt gcatccatcc
     1501 agttaaaaaa cctaattttt ctccataaat ttcttttata tataccatca ttccaccagt
     1561 ttttggtatc gcaactgata cctctgcagc tgtaagacca gctgttatag ttatgattcc
     1621 agctattaac catgccaata taccaagacc tggagctcct ccagttaatg tataaactgc
     1681 ttgtggttta aaaaatacac ccgctcctat aacagaacca acaacagttg ataatgccgc
     1741 tgatacgcca agagtctttt tcagttcatt actttccatt ttcttcctcc tcattaatcc
     1801 tatttaattt taatttcata gttaaataag catatattat gccaatacta tagaaaaata
     1861 gctttattat ttattaaaat aaaataaact ctacttagct tttgtaattt tttgctttta
     1921 atcaagttca aatataaaaa aattataaaa aacaaaaatc taaattaatg atacttatta
     1981 aaagtaaaaa t
//
LOCUS       DAMKOJ010000189         1975 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000189 DAMKOJ010000000
VERSION     DAMKOJ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1975
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.199"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            497..886
                     /locus_tag="PC592_003584"
     CDS             497..886
                     /locus_tag="PC592_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF4057503.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYKWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEEDV"
     gene            1380..1850
                     /locus_tag="PC592_003585"
     CDS             1380..1850
                     /locus_tag="PC592_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF4057504.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYQELFEQEIELDLGKNVTFRGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDNFDKFIEKLNSYKEVEFVHKPLKYEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLAEGYSAEETSKIIQHPIEFVKQCENSKQ"
BASE COUNT          875 a          161 c          319 g          620 t
ORIGIN      
        1 attaatgaaa aaatttaaac tttgtaagat ataaataaaa aaactctaaa atagaaggat
       61 ataactatat agaatgtttc aattaaacaa ggcaaaaatt ataatcttaa aattacaatt
      121 aacactattc ttaagaagta agaaatttag gaagtaggaa gtttagtaat aagttgtatt
      181 aagtaagaaa tttaggaagt aggattcact ggaatacaaa tatttaaaat caaataattt
      241 aaaagaaagg agagctactg gacaagtatc caaaatagat agctgagtac aaaatatttc
      301 ataaaattaa gcaatataat acgaaaattt tgacattatt tatatatatt taccatgtac
      361 aaatagctaa atttaggatt aagattgaaa aatatcttat aaatctgagc ttatataaat
      421 ccgtataaga tgtatttaat cgaagaattt tattatggat attgcttgtc tatattctga
      481 gtagcaaggt tttatcatga ctataaaaaa gttgccacaa tcagaattaa agataatgaa
      541 atttatatgg aaatcagatt ccaaagtaac atctagagat attgttttag gaatggagca
      601 aaaatataaa tggaaacaaa cgacaacttt gactctttta tctagattag tagtaaaaag
      661 atttctaaat tctcaaaaga tagataaata tacacattat gaagttttaa ttaaagaaaa
      721 ggaatacata ggagttgaaa ctagagattt ttttagaaat attcatgatt cttctataaa
      781 aagtttatta ttatcattac atgaaaatat taatctgagc aaagatgata tcttacttat
      841 tgaagagtgg ataaaaaatc taaaagaaga ggaggaagat gtataggcaa acgtattttt
      901 gtatagcatc aatataaatc gtgtgtagat atatttatat aattagtcta cttaagtaat
      961 ataataactt attataagtg agttataaca ttataatgtg aatctaaaac aggttaaatg
     1021 taaacataaa ttagtaatgg atattctatt taattaaatt taaaaaagct acctataatt
     1081 atataagtac taggtagctt ttttaatgaa gacaatgaga tttaaataga agtttaaaaa
     1141 taaactgtaa aagcttaaga tgataaaata aatagctatt aatgaagata ttgaagagac
     1201 agaagtgaag tgttaatata agatgttgaa aaagtaaaaa taagggctta ataaaagata
     1261 ctgaaaagta aaaatgaagg attaatagaa gggattgagg ttacataggt aaaagtgtta
     1321 atagaagata ttgaaaaaaa tagaaataaa gaacaaataa acaattagga ggaaaattta
     1381 tgaaatatca ggtttcatta ttagcagtga aggatatcga agtatcaaaa aaattttacc
     1441 aagaattatt tgagcaagag attgagttgg acttaggtaa aaatgtaaca tttagaggag
     1501 gatttgccat acaagaagac ttcgcatggc ttacagggat taatccagat acaattatac
     1561 aaaaatcaaa taatatggaa ctttattttg aggttgataa ttttgacaaa tttattgaaa
     1621 aactcaattc ttacaaagaa gtagagtttg ttcataagcc actaaaatat gaatggcaac
     1681 aaagggtagt gcgtatttat gacccagata aacatattat tgagatagga gagtctatgg
     1741 aagttatagc tagaaggtat ttagctgagg gatactctgc agaagaaact tctaaaataa
     1801 ttcaacatcc aattgaattt gtaaagcagt gtgaaaatag taagcaatga ttgtttaaat
     1861 tataattatt tagtagaaat taattgtagt ggaactaatt taagataata tataggatta
     1921 gtatttgact aatgttataa attaaattaa aatagagaaa agattaataa aggaa
//
LOCUS       DAMKOJ010000190         1970 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000190 DAMKOJ010000000
VERSION     DAMKOJ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1970
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.200"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            274..834
                     /locus_tag="PC592_003586"
     CDS             274..834
                     /locus_tag="PC592_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4057505.1"
                     /translation="MTNILKFKLLSFSKEKKEHSLEKKAIYGDKKAFENLIENNEEYL
                     YKMAFLYTKNEHDALDIFQDTVYKAFLNIDKLKEPSYFKTWITKILINTFNTKYKKTV
                     NYLNIRDYEHKIEEVNYQQIEDKIDLYDAIDRLDEKYKTPIILQYFQDMTIGEIAEIL
                     DINENTIKTYLRRGKASLYELLKEEK"
     gene            836..1870
                     /locus_tag="PC592_003587"
     CDS             836..1870
                     /locus_tag="PC592_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4179 domain-containing protein"
                     /protein_id="HDF4057506.1"
                     /translation="MSKYDDIKIPESLKRVRNSAIEKAYKDKKFKRDKKRFTMTVSIA
                     IIGLGLLGIGVSNPTFAQKILRVNEMIQAIQGIFTNNELSDSITTIGESSTRDGLTIT
                     VQNAYYSQNEITLEIELKTDKPFKNTKYSKVIVKDNKDESIDDFALMTKDFNTWINGE
                     ETKGIVYESPRFKYIDEYTLKGYWQINFKSPIENHKNYDTIKMSFGLNETNYDKKSNN
                     YKYTNSINGPWILEFPVKSNMDKVKIIKPDIRQDIITVKQVALSQTSLNLKLELEKQG
                     VIEYVEVKDDNGETLGGGMESSNPNKIDLDFGLKNVNQSPKYITIFAYGNIDNGKDES
                     KAIKIKINLE"
BASE COUNT          892 a          195 c          284 g          599 t
ORIGIN      
        1 atgtgaaatc gttaataaaa cttgtgggat ttgtatgatt attatcaaaa acatacctat
       61 aatcaaagag actatatgaa aactctcttt tttttataaa aacttatata taaataatgc
      121 aaatattaaa aagtaaataa atgttggaaa gattatgttt ctataagcta gtttctaaag
      181 agttattctg aaattagtta taaaatttat atttttgaaa ctttatatac aaaataatag
      241 tctaactaat gtgacaatat aaaggaggct gagatgacta atatattaaa atttaaatta
      301 ttatcctttt ctaaagaaaa aaaagaacat agcctagaaa aaaaagctat ttatggagat
      361 aaaaaagcat ttgaaaattt aatagaaaat aatgaagaat atttatataa aatggcattt
      421 ttatacacta aaaatgaaca cgatgcactt gatatatttc aagatacagt atataaagca
      481 tttttaaata tagacaagtt aaaagaacct agttatttta aaacatggat aactaaaata
      541 ttaataaata cattcaatac aaaatataaa aaaacagtta attatttaaa tattagggat
      601 tatgaacata agattgaaga ggtaaattat caacaaattg aagataaaat cgatttatac
      661 gatgcaattg ataggttaga tgaaaaatac aaaacaccta taatacttca atattttcaa
      721 gacatgacaa ttggtgaaat cgcagagata cttgatatta atgaaaatac gataaaaacg
      781 tacttaaggc gaggtaaagc aagtctttat gaactattaa aggaggaaaa gtgatatgag
      841 taaatacgat gatataaaaa tacctgaaag tcttaagaga gtaagaaatt cagcaataga
      901 aaaagcatat aaagataaaa agtttaaaag agataaaaaa agatttacta tgactgtaag
      961 tattgcaatt attggattag gattgcttgg aataggtgta tcaaatccga catttgctca
     1021 aaaaatactg agagtaaatg aaatgattca agcaattcaa ggtatattta ctaataatga
     1081 actgtcagat agtattacaa ctattggaga atcaagtaca agagatggac ttactataac
     1141 tgtccaaaat gcatattata gtcaaaatga aattacctta gaaatagaac taaaaacaga
     1201 taaaccattt aaaaacacta aatattctaa agtcatagta aaagacaata aagatgaaag
     1261 catagatgat tttgctctta tgactaagga ttttaatacc tggataaatg gagaggaaac
     1321 taaaggcatt gtatatgaat cacctaggtt taaatatata gatgaatata ctctgaaagg
     1381 atactggcaa ataaatttta aatcgccaat tgaaaatcat aaaaattatg atactatcaa
     1441 gatgtctttt gggcttaatg aaacaaatta tgataaaaaa tcaaataatt ataaatatac
     1501 aaattctata aatggacctt ggatattaga attccctgta aaatcaaata tggataaggt
     1561 taaaataata aaaccagata ttagacaaga tatcataact gttaagcagg tagctttaag
     1621 tcaaacatca ttaaacttaa agttagaatt agaaaaacaa ggagttatag aatatgtaga
     1681 agttaaagat gataatggag aaactttagg tggtggaatg gagagttcta accccaataa
     1741 aatagactta gattttggat taaaaaatgt aaatcaatct ccaaaatata taacaatatt
     1801 tgcctatggc aatattgata atggcaagga tgaaagtaaa gctataaaaa ttaaaattaa
     1861 tttagaataa tcaattatcc cttaaaagtt atttagaaat ttactaatta tagataaagt
     1921 taatgccctt gaaatccaaa taaatagatt ttaagggcat ttttattata
//
LOCUS       DAMKOJ010000191         1963 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000191 DAMKOJ010000000
VERSION     DAMKOJ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1963
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.201"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            25..1680
                     /locus_tag="PC592_003588"
     CDS             25..1680
                     /locus_tag="PC592_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057507.1"
                     /translation="MNLDFHYYGTYLAAKVAGYNDTDAKTIAYAAQYVDESDKSMILD
                     DVNFTLPTIQTNLEFKKYYADLASWGYKWDFESLNEIKKVWIPFHFLPGNLNNQYKYN
                     GVKESKCLTTSWKFKDGDDQKFRLMCLPNSETVSAIINDLIYFHSTEEYKLQFIGMRM
                     HVLADTWAHMYFIGKPEWYINDVKEFIAEESKYIEETKWTKAEEYRNNGWHSINFTGT
                     PDIGGYESISYLGHGRMGHIPDYGYLNYRYIPNWSSTDDKVKIEKNNQDNFFKAFCQM
                     VYALKCIKNGNDFNINQYDNLTAQQKTEVSKVIATRKNDQSEAWKKAIQALGYNPLEK
                     FDKNKWKNEFIKSSNKEKTDYYYFNLVAKKHVDYVTDFLEEKRLSLEEMFNGYCKFKN
                     FDDTQFAKNRNRVTKIILRGAYIVDAIQLVYDGKYKTPMHGEPFGGTMVSLDLDTDDY
                     IVKISGSIGLYEGGEPYPNSPTRTIGKITFLTKKGKTITAGHETMFKLYRNFTLEAPA
                     GKQIFALKGSYLIRKLREETSKRYLDCLEIANTKDCSVATSTK"
BASE COUNT          801 a          218 c          326 g          618 t
ORIGIN      
        1 aaaataaaat taagaggtga ttttatgaat ttagattttc actattatgg cacatatctt
       61 gcagctaaag tagctggtta taacgacact gatgcaaaga caattgctta tgctgctcag
      121 tatgtagatg aatcagataa aagtatgatt cttgatgatg taaactttac acttccgaca
      181 atacagacta atttagaatt taaaaaatat tatgcagatt tggcttcatg gggttataaa
      241 tgggatttcg agagtttaaa tgaaataaag aaagtatgga taccatttca ttttttacct
      301 gggaatttaa acaaccaata taaatataat ggagttaaag agagtaaatg tttaacgaca
      361 agttggaaat ttaaagatgg agatgaccaa aaatttaggt tgatgtgttt accaaatagc
      421 gaaactgttt ctgccattat aaatgacctt atttattttc atagtaccga agaatataag
      481 ttacaattta ttggaatgag aatgcatgta cttgcagaca cgtgggcaca tatgtatttt
      541 attggaaaac cagaatggta tattaatgat gttaaagaat ttatagcaga agaaagtaag
      601 tacatagaag aaactaaatg gactaaagca gaagaatatc gtaataacgg ttggcattct
      661 attaacttta ctggtactcc tgatattggt ggatatgaga gcatatcata tcttggacat
      721 ggtagaatgg ggcatatacc agactatgga tatctaaatt atagatatat tccaaactgg
      781 agtagtactg atgataaagt gaagatagaa aaaaataacc aagataattt ctttaaggca
      841 ttttgccaaa tggtttatgc attaaaatgt attaaaaatg gaaatgactt taatataaat
      901 caatatgata acctaacagc tcaacaaaaa acagaagttt caaaagtaat agcaacaaga
      961 aaaaatgacc aatcagaagc atggaaaaaa gcaatacagg cattaggata taacccttta
     1021 gaaaaatttg ataaaaataa gtggaaaaat gaatttataa aatcttctaa taaagagaaa
     1081 acagattact attattttaa tctagtagct aagaaacatg tagattatgt aactgatttt
     1141 ttagaggaaa aaagattgtc tttagaagaa atgttcaatg gatattgtaa atttaaaaat
     1201 tttgatgata cccaatttgc taaaaataga aatagagtga caaagattat acttagagga
     1261 gcttatatag ttgatgctat acaacttgta tatgatggaa aatataaaac tccaatgcat
     1321 ggtgaaccat ttggaggaac aatggtatct cttgatttag atactgacga ttacatagtt
     1381 aagataagtg ggtctatagg tttatatgaa ggtggagaac catatcctaa ttctccaact
     1441 agaacaatag gaaaaataac ttttttaact aaaaaaggaa aaacaataac agcaggtcat
     1501 gaaactatgt ttaaattata tagaaatttc actttagaag cacctgcagg aaaacaaatt
     1561 tttgcactta aaggttcata tttaatacgt aaattaagag aagagactag caaacgatat
     1621 ttggattgtt tagaaattgc aaatacaaaa gattgttcgg tagctacaag tacgaaataa
     1681 ctacatattg gatagctagt gttataatat atttaagaaa atagtataat atttatattt
     1741 acaatgaaag cactctttat tataaagagt gctttcattg taaatcatca agaacattac
     1801 taaatatacc ttaaaattga tttaaatagg tctttttatt tagaaataac agtcatataa
     1861 gttaaatatt aatatctaaa caatttaata atgaatatag aaagattaaa aggtagcaac
     1921 tagaactagt tattacctta cttttttctg attttttata tct
//
LOCUS       DAMKOJ010000192         1843 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000192 DAMKOJ010000000
VERSION     DAMKOJ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.202"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..1259
                     /locus_tag="PC592_003589"
     CDS             <1..1259
                     /locus_tag="PC592_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057508.1"
                     /translation="YINKLGDIEKRVVELTAKNVKKVYLRGIEILEEELVRLKNFYEL
                     MMSRKLDTNSIAYNDTLMELSSFFKSYIIKFEAQDIPVSIDYPLALDDMDIQGIYYVK
                     NYIESIDIENRFCNLFKKKDREKLFYDYGVTYKIDCDVILVNLFELIINNCIFSTILG
                     NEVTNLEISEYEYEFLEKQFKNICNNIAEDKVIVSEESNIIELIEVDDSFNTEADSNL
                     DYNDFEKITLILMEAIEVLVKRLRIEDEVVIRYIKKYEKRFIESVLSSIKSNTFKSMV
                     TVSKNKNEQLESYIVDDESKLDDESFRKIFNEILDSTSIIEKIRIIKENINAKKDFID
                     ILESECLFGEEYLMLFASLSELELAILGSVVFYEDIRMREINILEFLLNKKTETTLWK
                     IEYLKFMKRQSEDKIRSIEEHMNKIN"
     gene            1343..>1843
                     /locus_tag="PC592_003590"
     CDS             1343..>1843
                     /locus_tag="PC592_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF4057509.1"
                     /translation="MKEHIINNIEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGESGH
                     GCGHNLLGVAGVGAVVSTKKLIEENKFSGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHP"
BASE COUNT          769 a          130 c          353 g          591 t
ORIGIN      
        1 cctatataaa taagcttgga gatatagaaa aaagagttgt ggagttgact gctaagaatg
       61 ttaaaaaagt gtatcttaga ggtattgaaa tcttagagga agaattagtt agactaaaaa
      121 atttttatga actaatgatg agtagaaaat tggatactaa ttcaatagcg tataatgata
      181 ccttgatgga gctatcaagt ttctttaaaa gttatattat aaaatttgaa gctcaggata
      241 ttccagtaag tatagattat ccattggcat tagatgatat ggatattcaa ggaatttatt
      301 atgtaaagaa ttatattgag agtatagata tagaaaatag attttgcaac ttatttaaga
      361 aaaaagatag agaaaaatta ttttatgatt atggggtgac ttataaaata gattgtgatg
      421 ttatacttgt aaatttattt gaacttatta taaataattg tattttttct acgattttag
      481 gaaatgaagt gactaattta gaaatttcag aatatgagta tgaattttta gaaaagcaat
      541 ttaaaaatat atgcaataat attgctgaag ataaagttat agtatctgaa gaaagtaata
      601 taattgaatt gattgaagta gatgatagtt ttaatactga agcagatagt aatttggatt
      661 ataatgattt tgaaaaaata accttaatac ttatggaagc aattgaagtt ttggtaaaaa
      721 gattaagaat agaagatgaa gttgtaataa gatatattaa aaaatatgaa aaaagattta
      781 ttgaatctgt gctaagttca ataaaaagta atacttttaa aagtatggta actgtaagta
      841 aaaataaaaa tgaacaatta gaaagttata ttgtcgatga tgaaagtaaa ttggatgatg
      901 agtcgtttag aaagatattc aatgagatat tagacagtac gtctataatt gaaaaaataa
      961 gaataataaa ggaaaatatc aatgctaaaa aagattttat cgatatcctc gaatctgaat
     1021 gtttatttgg agaagagtat ttaatgttgt ttgcttcatt aagtgaatta gaattagcaa
     1081 tattgggtag tgtagtgttt tatgaagata ttagaatgag agaaattaat atattagaat
     1141 ttctattaaa taagaaaact gaaactactt tatggaaaat agagtacctt aaatttatga
     1201 agagacaaag tgaagataag atacgctcca tagaagaaca tatgaataaa attaattaac
     1261 aaaaaattgt gaataaatag aatgttagta tataatataa tttatgaagc atatcaaaaa
     1321 tacatatatt tggaggaaaa ttatgaaaga gcatatcata aataatattg aagaaataag
     1381 agaagaatta atagatttat ctaagaaaat atgggaaaat ccagaattag cttttgaaga
     1441 aaagtatgca agtagcatcc aaaaagaata cttaaagtca aaaggattta aaattgaaga
     1501 agtagaaaat ttacctactg gatttatagc aagttttgga gagggtaaac ctgtgattgg
     1561 catacttgga gaatatgatg ctttaccaga gctatcacaa tgtgtgagtg cagaaagaaa
     1621 gccattggta gaaggagaat ctggacatgg atgtgggcat aacctattgg gtgtagcggg
     1681 tgtaggagct gttgtttcta caaaaaaatt aatagaagaa aataaattta gtggaacaat
     1741 aaaatatttt ggttgtcctg ctgaagaaga aggtggagga aagacagtta tgtgtataaa
     1801 tggatgtttt gatgatgtgg attgtgcatt tacatggcat cct
//
LOCUS       DAMKOJ010000193         1839 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000193 DAMKOJ010000000
VERSION     DAMKOJ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.203"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            67..324
                     /locus_tag="PC592_003591"
     CDS             67..324
                     /locus_tag="PC592_003591"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057510.1"
                     /translation="MHNVDCNDKSVYIGNNELDRSKYLKENELLALFGDGASIDMKHN
                     SKLDMQISNPNLKSVNIYPYTPFVGLRGTLYIIEKILNIQY"
     gene            556..747
                     /locus_tag="PC592_003592"
     CDS             556..747
                     /locus_tag="PC592_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057511.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTKPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(835..1647)
                     /locus_tag="PC592_003593"
     CDS             complement(835..1647)
                     /locus_tag="PC592_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HDF4057512.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNRVTEISDDLDSILTNVVEKIK"
BASE COUNT          717 a          240 c          237 g          645 t
ORIGIN      
        1 tatgcaaaat tctatgaagc aggaaccctg tgactttagt catgggaggt tcagagagtt
       61 aatgtattgc ataatgtaga ttgtaatgat aaatctgtgt atattgggaa caatgaactg
      121 gatagaagta aatatttaaa agaaaatgag ttattagcat tatttggaga tggtgctagt
      181 atcgatatga aacataattc aaagttggat atgcagataa gtaatccaaa cctaaaaagt
      241 gtaaatatat atccatacac tccttttgta ggattaagag gaactcttta tataattgaa
      301 aaaatactaa atatacagta ctaaatatat aaaaaatatt atttaaatac atatacaata
      361 cataaaaaag tttttattaa gaaaatgttg ataaaaaaaa ggtacattta ttaaaaaatc
      421 aatctctact tgctaaaata attatgaatt atgttagaaa ctgtaatata ttggatataa
      481 tataataaac gggtaaactt tggattaaga ggattatata gtttatctta attatagggg
      541 aagtgaggat atattatgga aagattaatg gaactcatag aaagaaaatt tttaaaggat
      601 gtagaacttt tagaattaga agacatagaa aatgtaatag aatgcaaaat gactaagcca
      661 tataatgctc attataatga atacttagta aaagtaaaaa atggagatga agtagaagaa
      721 tattttgtgt atttaaaaca tagataaaca taaaagaggt ttatatttat ttgtatgatt
      781 ataaaataaa tataagcctc ttttttgata aatataaaat tataaaattt ttatttattt
      841 aattttttca acaacattag tcaatattga atctaaatca tcactaattt ctgtaactct
      901 attatgagta atatctataa tttctttagt cataggaagt tctcctaaaa gctctaagtc
      961 taaatcatct aaaaactttt cagtagattc tccttcaaat aacttgattt ttttagaaca
     1021 atcagggcat tggatataac tcatattttc aataactcca aggacattta tgttcatttt
     1081 tttagccata ttaacagctt ttgatacaat catagatacc aaatcttgag gtactgaaac
     1141 cataactatt ccacttatag gaatagattg cataactgtt aaggcaacat ctccagtacc
     1201 aggaggcata tctattaata aatagtctaa ttcttcccaa agtacatcag tataaaattg
     1261 ctttacaact cctccaagta aaggtcctct ccaaacaaca ggttcattct catcatctat
     1321 cataagattt atagacatta cttttatgtt atttgagttt tctacagggt aaatataaga
     1381 gccatcagaa taagctttta cattttttac acccataagt ctaggaatac ttggtccagt
     1441 tatatctgaa tctaatatac caaccttata tcccattttg tttagcttat tagcaagtaa
     1501 agcagttaca gttgattttc caactccacc cttcccactc ataacaccaa ttatttttcc
     1561 aaatttattg ttagggttat tttcaataga acaatttgat tgactattac aatttccctt
     1621 tgatggacat gaattacaat ctgccatatc tattacctcc aaactttaat atttattaga
     1681 ttatttgtaa cctacatata ctattttagt acaattgaac cataaagtca ttatttaaaa
     1741 gtaacttaga agattttcta ttaatttatt catagactat agcaaaaaga atacaataaa
     1801 aaaattataa cattcttgaa aaagtgatta tttcaattt
//
LOCUS       DAMKOJ010000194         1835 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000194 DAMKOJ010000000
VERSION     DAMKOJ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1835
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.204"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..332)
                     /locus_tag="PC592_003594"
     CDS             complement(<1..332)
                     /locus_tag="PC592_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4057513.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMGFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDANSIILKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQG"
     gene            complement(818..1780)
                     /locus_tag="PC592_003595"
     CDS             complement(818..1780)
                     /locus_tag="PC592_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4057514.1"
                     /translation="MISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYTDDE
                     LEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVYKIGG
                     GLTSKVMSSIASSLSKHNTTPTDPGTSGGKTVMIDPGHGGSDTGTTGKPLGGIKEKDY
                     TLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNASDTTG
                     NGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLYVLRN
                     NDMPAVLVECAFLDNEKDMSLLNTSDKVKEMGTQIGKGIEDSLK"
BASE COUNT          573 a          306 c          215 g          741 t
ORIGIN      
        1 ccttgtagtt cccaaacatt tagatattct gggtctttat tataattaat agttccctca
       61 tacgactcag ttgattgatt gtagtttaga gttgtgtcta atggcatatc ataacattta
      121 tattttaata taatgctatt tgcatctggt ttttctttaa atttgacgct aacttttgat
      181 ttactaccta aaacgatact ttttttctct aagtttatat ttaaatcagc attattttcc
      241 atagcattag attcagtagc aaatcccatt gtaggtgcaa cgattgccat tgaaagaatc
      301 cctgttgtta ataattttgt atttcttctc atattaatct ccttatttaa cataaatttc
      361 tactttgttt tttaaccttt taacttttga aaatatggca aagtgtatct atctaaaaat
      421 ataaataagt acataaagat aaacttataa aactcaaaaa ataaaaaaat taaatatatt
      481 taatacattt aattatttat actatagcat ttattaccat aaaaatccac aaaaaaacac
      541 aataaagtat agtaattgaa cttttactgt gtatcacaaa tgaatacgcc aactcttgac
      601 gattagctat aaccttaaaa tatgtaaatt ctttatataa cataaattct tttacaatta
      661 actacaaaaa gactatatat acatcactta gcacttatat gcacaatgta tatatagtct
      721 ttattactat tgtaattaca ttcttatctt atagctttag ttaaaattta aaattgcaaa
      781 ttaatttatt ttaaattttc tatgctctca ttgttggcta ttttaatgaa tcttctattc
      841 ctttacctat ttgtgtaccc atttctttta ctttatctga tgtattaagt aaactcatat
      901 ctttctcatt atctaaaaat gcacattcta caagtacagc tggcatatca ttatttctta
      961 aaacatataa ataatctttt gtagggtcag ttgatagtgt tcttgttttt gcacctctat
     1021 tttttagatt aaatttctct aaaattctat ttaatatatt tgtagctaca gtcttagtag
     1081 ttcctccatc tttgtcctta agcttataaa atacttctac accattccca gttgtatcag
     1141 atgcattata gtgtatactt gtaaataaat ctggtctcaa agagttagat agagcagttc
     1201 tatttccaag agataaagtt ttatctgtgt ctcttgtcat tattacattg aacccctttg
     1261 aacgtaaata ttcagttgtc gcaagtgaag tatttaaggt atagtctttt tctttaatac
     1321 ctcctaatgg tttacctgtt gttccagtat ccgaaccgcc atgccctggg tcaatcataa
     1381 ctgtcttccc accactagtt cctgggtctg ttggagttgt attgtgttta gataatgatg
     1441 atgctataga actcattacc ttagaagtca atcctcctcc tattttatat actttattgg
     1501 ctgatttagc ttctaagttt tctttatggt atgcagatac atacgtcttt ggtgttataa
     1561 gtattggaga ttttaagtta gcagccaatg gacctgctgc taaagcatca acaagtacat
     1621 ctgatttagc tactaaaaca gcttccaact catcatctgt atagaatttt tttattacat
     1681 ttgcatttgt ttcgtgtcta tctgctccgt atactctatt attagtaaca ctatccttag
     1741 ttattccatt taccttattt ataacatttg ttgatatcat ttgaggacca cctataaaat
     1801 aagcactttg taaatcctca ctctttaacc attta
//
LOCUS       DAMKOJ010000195         1832 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000195 DAMKOJ010000000
VERSION     DAMKOJ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.205"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            81..548
                     /locus_tag="PC592_003596"
     CDS             81..548
                     /locus_tag="PC592_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF4057515.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALITRILYFSDYFVVILFLIFIINSTKYSPFILENVKRFKMMGCCLLVNTIIECVVG
                     YKSNTSLIMIFGDNSGGISPLMVISFIFALMCFVIAETFDKAIKIKKDNDLTI"
     gene            559..774
                     /locus_tag="PC592_003597"
     CDS             559..774
                     /locus_tag="PC592_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057516.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDENE"
     gene            917..1090
                     /locus_tag="PC592_003598"
     CDS             917..1090
                     /locus_tag="PC592_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HDF4057517.1"
                     /translation="MKRKLSTYFKGYVLGLCIAFLLFSFILKKLMISNIIGIVIGTGI
                     AFLLICLFNKKRK"
BASE COUNT          668 a          168 c          228 g          768 t
ORIGIN      
        1 tatcaataat ttattattgt aattcaataa attatatatt ataatcaata atatacttta
       61 tataaaggag atgaaatttt atgattacaa aattttttag taatatatta tcagtatttc
      121 tatattttct attatcactt ttaggtgttg ctggtataat attcttatgt atgataccta
      181 tgtttttata tgattttagt tctgacaaag taattgcttt aattacaaga atactatatt
      241 tttctgacta ctttgtagtc atcttattct tgatatttat aattaatagc actaaatact
      301 ccccttttat acttgaaaat gtaaaaagat ttaaaatgat gggatgttgt ttattagtaa
      361 atactataat tgaatgtgta gttggttata aatcaaatac tagtcttata atgatatttg
      421 gagacaatag tggtggtatt tcaccactta tggttatttc ttttatattt gcattaatgt
      481 gttttgtaat tgctgaaacg tttgataaag ctataaaaat aaaaaaagat aatgacttga
      541 cgatatagag gtgatgttat ggcaattgta gttaatctag atgtaatgat ggcaaaaagg
      601 aaaatctcac ttaaagattt ggcagaaaaa atagatatta caaatgcaaa tttatcgatt
      661 ttaaaaactg gaaaagcaaa agctattcga tttactactc taaatgaaat ttgcaaagct
      721 ttagattgtc agccaggcga tatacttgaa tatgtagaag atgaaaatga ataaaaaaga
      781 gtgtttaaaa acactctttt ttattacaat atttacttac tctatctaat agttgtaatc
      841 ttttagatac tctttggagt tacaacactg ctatactcta attaaataag tcaaatctat
      901 acaagttggt gattatatga aaagaaaact ttcaacatat tttaaaggtt atgttttagg
      961 tttatgcata gcatttttat tattttcttt tatattaaaa aaattaatga tatcaaatat
     1021 cattggaata gttattggaa ctggaattgc atttttattg atttgcctat ttaataaaaa
     1081 aagaaaataa cattctataa gaaggttttt agtaagttta caagagaaat atattaattt
     1141 attaaactta gtaaatatca aatataaatc aaaaaaataa aattcaaact ataatatgtt
     1201 tctataaaat ttggtataac ttatttactt ggtttattat tgtatttgaa aaaatttatt
     1261 aaacctaaaa gtttttcaaa atttatgatg gttttatcac tatcttcagt tgctattgca
     1321 aagttttata tgttgagaaa aactaatgaa aattataaat tttatcgatt agtaatattg
     1381 ttttttattg attgttgttt actttttatt tttcaatcat ttaagctaat aaatcttact
     1441 ataagtatca ttagtttata tttattcttt tttatctgag gaatatggtt agagatgttt
     1501 cttacaaaat gttttatttg ataaattcgt taaaaaaata ggtattatag tggtagatat
     1561 ttgttgaagt ttatgtattt acccttacaa ttcacattgt ataatctaga cactcaaaca
     1621 atttaaagtt taattcattt gatatatgga atcggacttt atatattttt aggttatgtt
     1681 tatataaaag ccaaaaatat tctgttttgt tctataattc ataatttggt taatagttta
     1741 gatattattt gtaacttttc taaaataacg cttagttatt atattatttt agaaatactt
     1801 atatttatat cattgttttt tcttcatctt ct
//
LOCUS       DAMKOJ010000196         1797 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000196 DAMKOJ010000000
VERSION     DAMKOJ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1797
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.206"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            161..1210
                     /locus_tag="PC592_003599"
     CDS             161..1210
                     /locus_tag="PC592_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF4057518.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWVQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1359..1706)
                     /locus_tag="PC592_003600"
     CDS             complement(1359..1706)
                     /locus_tag="PC592_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF4057519.1"
                     /translation="MHENKKNLLDGSLAQYNDVAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          666 a          251 c          278 g          602 t
ORIGIN      
        1 tttatccaat attacgcatt attaaaaaga ctaaacataa aactgaaact tattattaag
       61 tttttgtaga aatattataa gtatagatac atttttgtaa caactacaat gaatatttaa
      121 tactatatac tattcgtatg tcttatggga ggtatttatt atgtttaaaa aaatagtcgc
      181 aatagcaagc tctatcattg taagtacaat atgtctaact ggatgtgatt ttaactctaa
      241 tgacaaaaaa gatgaatctt cttcgtctaa aaatctggat aaagtaacta tagcagaagt
      301 tactcactct gttttttatg ctccacagta tgctgctatt acgaaaggat tctttgaaga
      361 tgaaggtata aagattgacc ttataaatac ccaaggtgca gataaaacta tggcagcttt
      421 aatttcaggt gaagcaaacg taggtttaat gggccctgaa gcatctatat atgtatataa
      481 tcaaaacaaa aacgattatg cagtgaactt tgctcaattg acaaaaagag atggtagttt
      541 tctagttgct aggaaaaaaa tgcctaattt ctcttataat gatttaaaag gaacagaaat
      601 attaggtggt agaaaaggtg gagttccact aatgactttt gaatatgttc taaaagaaaa
      661 aggtcttact attggagaaa acctaaaggc aggcaatgtt aatgtaagaa ctgatgtaca
      721 atttggtgta atggctggag cttttgcagg tggagagggg gactttacaa cagcatttga
      781 acctactgca acagcaatgg aaaaagaagg tagtggatat atagttacat ctataggaaa
      841 agattctgga gaaatacctt ttacagcata ctctactaca agatcataca tgaaaaacaa
      901 taaagattta attcaaagat ttacaaatgc tgtttataaa ggtcaattat gggttcaaca
      961 agcatctagc aaagaagtag ctaaggctat gcaacctttc tttgaagata tatctttaga
     1021 agatttaaca acagttgtag atagatataa atcaatagat gcatggtctc aaaaccctgt
     1081 attaaaagaa gaaggtctga agaaattaat gactgttatg aaggaagcta aagaattaga
     1141 taaggaagca ccttataaag atatcgtaaa cactgagttt gcaaacaatg ctataaagaa
     1201 tattaaataa aatatattac ttttgcctag atattttctc gattttatga ttaaaattaa
     1261 caaaaatata aaaagagcct tttaaaagac tctttttata tttgagatta aagtttatat
     1321 aataaaatag aatcaaagta ctaattgtac ttatatatct atcctctata ttctgctcca
     1381 gcattaattt ttgtaatttg aacagctacc atttcttcat tgcttccatt agtaatttca
     1441 tgccattctc ctgttggtac aaatacagta tcgccgtttt ttacatcaca ttcatgctca
     1501 ccaagtttca ttttaccttc tccttttagg aacacaaata tttgttctcc attaggatgt
     1561 ctatgagcat taagaacttg attaggttta aaataataaa cttctgaagt tatatcgtta
     1621 ccagcaaata ctggtatttt tggaactgct acatcattat attgagctaa gcttccatct
     1681 aatagattct ttttattttc atgcatacta gaaatacctc ttttctatat tatatattta
     1741 ctattattat tccaatataa gaaaatagta ttctcatctt gcataatagg aataaaa
//
LOCUS       DAMKOJ010000197         1777 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.207, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000197 DAMKOJ010000000
VERSION     DAMKOJ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1777
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.207"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>1777
                     /locus_tag="PC592_003601"
     rRNA            <1..>1777
                     /locus_tag="PC592_003601"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          520 a          366 c          519 g          372 t
ORIGIN      
        1 ggacatatca taacgaagag gtatcgtaat tgaagaggtt tggaaagacc caccacagaa
       61 ggtaatagtc ctgtatgtta aacgagaaga cttcagatat gatccagagt accacgggac
      121 acgtgaaacc ctgtgggaag caggagggac caccctccaa ggctaaatac tacctagtga
      181 ccgatagcgt atagtaccgt gagggaaagg tgaaaagaac cccgggaggg gagtgaaata
      241 gaacctgaaa ccctgcactt acaagctgtg gaagcacatt tcttgtgtga ccgcgtactt
      301 tttgtagaac gggccaacga gttacgttaa gtagcaaggt taagcactta aggtgtggag
      361 ccgtagcgaa agcgagtttt aactgagcgt tcagttactt gacgtagacc cgaaaccggg
      421 cgacctaccc atgagcagga tgaagcgaaa gtaaaatttc gtggaggtcc gaacccacga
      481 gcgttgaaaa gctcggggat gacttgtggg tagcggtgaa attccaatcg agcccggaga
      541 tagctggttc tccccgaaat agctttaggg ctagcctcaa ggtgagagat acggaggtag
      601 agcactgaat gtcctagggg gtattgcacc taccgaagac tatcaaactc cgaatgccgt
      661 catcttatac ttgggagtca gactgtgggt gataagattc atagtcgaaa gggcaacagc
      721 ccagatcgtc agctaaggtc cctaaatgta agttaagtgg taaaggatgt gggattgcac
      781 agacaaccag gatgttggct tagaagcagc cactcattca aagagtgcgt aatagctcac
      841 tggtcgagtg atcctgcgcc gaagatttcc ggggctaaaa cttactaccg aagctacggc
      901 atcagtaatg atgggtaggg gagcttccca tacgggttga agcatgaccg taaggacatg
      961 tggacagtat gggagtgaga atgttggcat gagtagcgag atgtgggtga gaatcccaca
     1021 ggccgtaaac ccaaggtttc caggggaagg ttcgtccgcc ctgggttagt cgggacctaa
     1081 gctgaggccg aaaggcgtag gtgatggaca acaggttgat attcctgtac taccgataac
     1141 cgtttgagag aagggatgac acagtaggat aagctaagca cactgttggt tatgtgtgcc
     1201 caagcattga ggcagtcaaa gtaggcaaat ccgctttgat aatgctggga tgtgatgggg
     1261 agcgaaattt agtagcgaag tagctgattt cacactgtca agaaaagtct ctatcgaggt
     1321 taaaggtacc cgtaccgcaa accgacacag gtgggtgagg agagtatcct aaggccagcg
     1381 agagaactgt tgttaaggaa ctcggcaaaa tgaccccgta acttagggat aaggggtgcc
     1441 accatcaggt ggccgcagag aataggccca agcgactgtt taccaaaaac ataggtttct
     1501 gctaagtcgc aagacgatgt ataggagctg acgcctgccc ggtgctggaa ggttaagggg
     1561 atctgttaga gcaatcgaag cagtgaactt aagccccagt aaacggcggc cgtaactata
     1621 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
     1681 cgatttgggc actgtctcaa caacagactc ggtgaaattg taattccggt gaagatgccg
     1741 gatacctgcg acaggacgga aagaccccat ggagctt
//
LOCUS       DAMKOJ010000198         1689 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.208, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000198 DAMKOJ010000000
VERSION     DAMKOJ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1689
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.208"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(370..1077)
                     /locus_tag="PC592_003602"
     CDS             complement(370..1077)
                     /locus_tag="PC592_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF4057520.1"
                     /translation="MIFTKSNKYDKEFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLANEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISVDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSIKWWNELWSDSESVTVEKCEALNCHDEAWQDWLNCDNSYARNDKKMME
                     VENGKYFNTISLVARVK"
BASE COUNT          539 a          291 c          149 g          710 t
ORIGIN      
        1 tacttaatca ttttgaaatt taatttaaag tataataaaa tatataaaaa aacatctaaa
       61 atggtactat aaaatcttta atcttcatca atatcttttt tgccttttat tgttataact
      121 gcttttttat taattttttc tcataaaata aacatttagt attaaaatat atatagcgca
      181 atagtatttg acatctaacc ttagaaaaaa taaaaatgcc caattgcact aaaaaattcg
      241 attgggcata aataatataa aaaatcattt tttatataaa ctcttctttt aacttacgtt
      301 tttatttaac ttctgctttc attcaactta tatttctatt cgtttaatac tctcacttat
      361 cttatacttt tatttaactc ttgctaccaa ggaaattgta ttaaaatact ttccattctc
      421 tacttccatc atttttttgt catttctagc gtacgaatta tcgcagttta gccaatcctg
      481 ccaagcttca tcatgacaat ttaaagcttc acatttctct accgtcacag actcagagtc
      541 agaccaaagc tcattccacc atttaattga atggaagttc atgttgtctt gccaaaatgg
      601 aatgagttca tctggtatac aatccacaaa gtcttctttt aatccaggca ttgccatagc
      661 aagtattccc ccctctttta caagaggtga tatatgatta tccaaaaaac cttctttgtt
      721 tccaaaatag tgataagaat ctacacttat cactgcatca aagaaacctt ctgcataagg
      781 taattcatgt gcctctgcct gtattggaaa tattttgtca tccaatttaa actctttaaa
      841 tcttttatag ttttcagttg gttctatcca taaatctgtt gcaaatacag tagcatcaaa
      901 ttcatttgct agaaatatcg aggatatacc tttcccacat cctaaatcta aaatacgcat
      961 ccccttttct agttttatct tacttgttaa ttcttccaat atctttatac aattaggtcc
     1021 catcatattt ttcataagaa attccttatc gtatttatta ctttttgtaa atatcattct
     1081 atctttcctt tccctatcaa ttattattta ttaaatttta tacgtttgat tttttatttt
     1141 ttatatgctt cttataatga gcaatctctt ttttattcat tctttaacag gtaattttaa
     1201 tgagtaattt tatccactct acaataatca ctttaatgag taattttatc cactctatta
     1261 tagttatttt aatgggtaat tttatccact ctacaataat tactttaatg agtaatttta
     1321 tccactctat tatagttatt ttaatgggta attttatcta ctctacaata atcaccttaa
     1381 tgagtaattt tatccactct attatagtta ttttaatggg taattttatc tactctacaa
     1441 taatcacctt aatgagtaat cttatccact ctattatagt tattttaatg ggtaatttta
     1501 tctactctat aatagtcact ttaataagta atcataattt ttatatcatt ttagatactt
     1561 actctaataa gaagtcgttt tctgatactt gataagtttt aattacttcc actttaacct
     1621 atatactaat taacttattt aatttagtgt atatttgaca ctttaccttt tattatacca
     1681 tttattctc
//
LOCUS       DAMKOJ010000199         1556 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.209, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000199 DAMKOJ010000000
VERSION     DAMKOJ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.209"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            110..1546
                     /locus_tag="PC592_003603"
     CDS             110..1546
                     /locus_tag="PC592_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HDF4057521.1"
                     /translation="MKFYKRILTLILSISFVFANIQLANAISSVEKIQGKNKYEIAGK
                     IADKTAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKSPIILTNGQSIPFSTSGLKSYAIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHEPMVLVNDGSNKSV
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGIVKNIKPTTRTIKDGMYKVGKDIS
                     AGEYLITSNSGSYDSYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMI
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNNSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          638 a          167 c          263 g          488 t
ORIGIN      
        1 aacatggtct aatataattt gtaattttac ataagtttgt taagtacata actaacctaa
       61 gagtatgtat ttatatatta aaattttatt ctggggggac aattttatta tgaaattcta
      121 taaaagaata ttaacattga ttttaagtat ttcttttgta tttgcaaata ttcaactagc
      181 aaatgcaata tcatctgtag aaaaaataca aggaaaaaat aagtatgaaa tcgcaggtaa
      241 gatagcagac aaaactgcat ataaaactgc tatattaatt aatactagta actctatcgc
      301 agatgggtta agtgcaagtg gactagcagg agctttaaat gcccctatac tattaactga
      361 aaaaaatact ataccaactg aaacgtctgc aagattaaaa aatgtatcaa aagtttatat
      421 aattggagga acatattcta ttagtacatc tgtcgaaaat tcattaaaat ctaagaaaat
      481 gaaagttgta agaattaagg gaaacgatag aataaaaaca agttataatg ttgcaaaaga
      541 aataaattcg ataaaaaaag ttaatactgt tatgttaacc aatgcatata aaggagaagc
      601 agatgctata agtattgcat ctgtagcagc aagagataaa tcaccaataa ttcttactaa
      661 tggacaaagt ataccttttt caactagtgg tttaaagtct tatgcgatag gaggaacagc
      721 ttcaatgagt actactttag taaacaatac taaatctacc agactaggag ggagtactcg
      781 ttttgaaact aataaagcaa taataaataa gttttataaa gatgcgagag agttttatat
      841 agctggagct tatgaattaa caaatgcact tgtaggttct tctttatcaa aacatgagcc
      901 aatggtttta gttaacgatg gtagcaataa aagtgtttta aaaaatgcta agaaaataac
      961 ttccatagga tatatagatt caaatatagt acaacaatgt ttaaatatta caaatggaat
     1021 tggagatatt aatactggaa ttgtaaaaaa tattaagcct actacaagga ctataaaaga
     1081 tggaatgtat aaggttggaa aagatatttc agcaggtgaa tacttaataa cttcaaattc
     1141 aggaagttat gattcttatt atgaagttac aagtgatagt acaggtaatg ctgatagtat
     1201 actttcaaat gatattttta gtgggactag atatatcact ttaaagaatg gtcaatatat
     1261 taaaattgag gattcaacaa tgatattagc aaaatatgct aaagcccaga aagccaagaa
     1321 tggtaagttt ggaaatggta tgtataaaat tggattagaa attcctgctg gagaatatat
     1381 tataatgtca aattcttctg atgcatatta tgaagttaga aataatagct taggtaatgc
     1441 agaaggaata gttactaatg acactttttc aggaagaaga tatataacag ttgaagaagg
     1501 tcaatattta atattaaatg attgttattt aattgaaaat gaatagatgt aattgt
//
LOCUS       DAMKOJ010000200         1514 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.210, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000200 DAMKOJ010000000
VERSION     DAMKOJ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1514
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.210"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(95..646)
                     /locus_tag="PC592_003604"
     CDS             complement(95..646)
                     /locus_tag="PC592_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HDF4057522.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNREDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMHISYKMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
     misc_binding    complement(798..1061)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT          517 a          234 c          151 g          612 t
ORIGIN      
        1 ttgaacaaca taagaataaa atatttataa tctactttat tcttacgttg ttcagttatt
       61 ataatagttt ataaagtaaa atattatttc gtatttaagc ttgataacta actcttctta
      121 ttgatagact aacaatcttg aataaaaata ttcctgcaac tagatttatt aaaacagctg
      181 gtaatactac tgctaagaat aaagctgtga atgaagcccc tggaagacca actatagctt
      241 gagctgctaa taaaaagata gttccactta caagagttcc tattggcatt attattgcaa
      301 ctactacagt atcttgtgtt ttcttagcta atttttttat gaaaggcatc ttataactaa
      361 tgtgcattaa taaaaatact atatttgctg taagagtttt atctattaca ttaggaattt
      421 gacctcccgg aaaacttgat gtaagtgctg taaatattcc tgttactata cctgctatta
      481 aacaagtttt ataatcctct ctatttaaaa ccaatattac aaataacatt gctagtggta
      541 catctggttt cattggtaat cctatagctg gtgtgatttg atgtatcaat aatcccatcg
      601 ctaaaagtat tgcatttaaa gttaattttt ttgtatttgt tttcattttt tgtacttcct
      661 cctatttttt taattttcaa tttatttttt tgccaaccta ctatatcatc atctttagct
      721 ttggaaattc ataacatctt tttcaccacc ttctatcttt taaattttca gtaaaataaa
      781 aaaactccgt cctaaactaa taggacggag attatccgcg ttgccaccta aattatataa
      841 aaattaatat aaaattcaat tttcatatat ctcattatca ggtacttaca taccttattc
      901 gctataacgt gcgactgacg ataaagtcta ctctcaaaac tatgatttca atttattcct
      961 ctaagggcca ttcatcaaat tttttctcgc taagattcca ccatcctcag ctctctatac
     1021 tgaacctaaa tttaactact cttccttgtc ataggattta atttattgta ttaaattttg
     1081 ttgttaaaat aatgatattc ttttttctaa aaaatgtcaa cactttttat aaaaaatata
     1141 ttttgtaatc tattttttta taaaaaaagt aaattacact atacatttct ttccacatac
     1201 aaaattctat gaataattac tttaatagtc taataatctg atttttagct ctaattctgc
     1261 ctttattaat tttatgaata attattgatg taattttata ttttgatgca tgaggaacta
     1321 aattcttcaa agttaattaa gtacatttat caaaaattca tctcatttac catcatttaa
     1381 tactcatttc tgtattattt atatacctac tttgaaacag aatactactc tgttttaatt
     1441 acataatgtt attaacaaaa ataataataa ttagaaaaat gatattcttt taattatttt
     1501 tagtaaaact tttt
//
LOCUS       DAMKOJ010000201         1267 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.211, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000201 DAMKOJ010000000
VERSION     DAMKOJ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.211"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            159..1235
                     /locus_tag="PC592_003605"
     CDS             159..1235
                     /locus_tag="PC592_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF4057523.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASVLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYKDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT          500 a          176 c          219 g          372 t
ORIGIN      
        1 ggtgcgaaat atatgttttc ataaaatata taaaataaat tatatataaa aaataaattt
       61 tatgttgaca tagttaattc agcttgatat tatagttatt aaaaataagg acagtaaaaa
      121 cgctatccat attacaaact aaaaaggggg gaattataat gagtaagaaa ttatttattc
      181 ctggtcctat tgatgttaaa gaagaagtct tgcaaaagat ggctacacca atgataggac
      241 atagaggaaa agatgcatct gtactccaaa agagtataag tgaaaaaatg caaaaactat
      301 tctatacgaa caacacgata cttttatcca cgtcatccgg aactggttta atggaaggct
      361 ccattcgttc ctgtacatcc aaaaaggcag cagtattttc ctgtggatcc tttggtgata
      421 gatggtacaa aatggcagtg gctaataatg tcccagcgga tatatttaaa gttgaattag
      481 gagaggcaac aacgccagaa atggttgata aggtgctttc taccggagaa tacgatttaa
      541 taactgtaac tcacaatgaa acttcaactg gaataagaaa tccaatagaa gaaattggag
      601 aagttgttaa aaagtataaa gatgtaatct actgtgtaga tactgtaagt tcagccggtg
      661 gaataaaagt cgaggttgat aagattggaa tagatatttg tataacatca gtacaaaaag
      721 cactgggatt accaccagga atgtctattt gcacattttc tcaaaaagca atcgatagag
      781 ctaagcaagt accttttaga ggagtatatc ttgatttgtt agcaatgtat gaatacttaa
      841 tcaagaaaaa ctaccaatac ccttcaacac catctctttc tcacatgttc gctttagatt
      901 tccaattaga taatatatta gatgaaggcc tagataacag attcaacaga catgaagaca
      961 tggcaaactt agttagaaac tgggctaaaa aacacttcca aatttttacc aatgaaaatc
     1021 acttatccaa tacacttact gttatagaaa atactcaagg tattagtgta tcaaatttaa
     1081 attcaaaatt acaagaacga ggattccaaa tagcaaatgg ctatggagat ttaaaagaaa
     1141 aaacttttag aatttcacac atgggtgact atactgtcga agatgtacaa gaattattag
     1201 ataatattga tgatatatta ggttttaata aataatattg taaaaatatg tatattttaa
     1261 gataaat
//
LOCUS       DAMKOJ010000202         1248 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.212, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000202 DAMKOJ010000000
VERSION     DAMKOJ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.212"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(178..420)
                     /locus_tag="PC592_003606"
     CDS             complement(178..420)
                     /locus_tag="PC592_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057524.1"
                     /translation="MNRIAYQTLTVSNSLSFLRPATPVSILKSSGVATHTLISTDKHS
                     NGYNFSYAAHSDEGVRTNLLSKLKGKKISYYKVYWE"
     gene            561..1103
                     /locus_tag="PC592_003607"
                     /pseudo
     CDS             561..1103
                     /locus_tag="PC592_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
BASE COUNT          467 a          140 c          187 g          454 t
ORIGIN      
        1 ataaaaaggg actaaattct attagtcctc tttttatact tatatagctt ttttacaaat
       61 aaattttatt attatgtaat aaaatttagt agttgtttct gctaaatttt tattgatttt
      121 ttgaaataga tatttattct tttcaatttt catttgatta aagtcataaa cttttcttta
      181 ttcccaataa actttgtaat aagaaatttt ctttccttta agtttactta acaagtttgt
      241 tcttacgcct tcatctgaat gtgcagcgta tgaaaaatta tatccatttg aatgtttatc
      301 tgtagatatt agtgtatgag ttgctactcc actacttttt aatatactta caggtgttgc
      361 tggtcttaaa aaacttaaag agtttgatac agtaagtgtt tgatatgcaa ttcgattcac
      421 ccaatgtatt ttaaactctc ttgctccagc ccaagaaggt gatctattac tagtagaata
      481 ataataccat ggattattat tagtccagaa tgttactcca gcctcatata agcattgtga
      541 aacaaagtta gcataatctc catatccatc cttttagtga tggtaatgga agaacatcaa
      601 gagcattatc atatctatat ctgattgata aaggatatga tacttttaaa gagttttcaa
      661 tatcatatat gatatctaaa aacagaacta agtattataa ggctatactt gatgtagaga
      721 ataagggata taatttaact gtatttatag agttcatgct aaagtccata atgcaatcta
      781 taaatgaaat gagagacatg catgatagga attctttaga gagtgtgttg aaagaagagt
      841 tatttgaaaa tgacattact ctatcagcaa cagaagaaca tatattaaaa tatatctgta
      901 gtaaagataa ctattctatg acattggaaa actatattaa aaggaataaa agtagatact
      961 taaaggctgg aataaaagaa atagacttaa ttgaccagtt gatggaagtg tttaataatc
     1021 ttgaagaaat agagctttta tcaagggaaa aggatgtata taaagttaat gagaagtact
     1081 taaaaatgct tgatatagac taatttagat aatctagaga gggaatatat gaataataag
     1141 aaaaaggcat tcttaatttc tggtgctata aatgtaattt tattaataat tgtttttacg
     1201 ttatttcgtt ataatattat agaaaatagt acaaaaaata tgataata
//
LOCUS       DAMKOJ010000203         1227 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.213, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000203 DAMKOJ010000000
VERSION     DAMKOJ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1227
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.213"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(274..1143)
                     /locus_tag="PC592_003608"
     CDS             complement(274..1143)
                     /locus_tag="PC592_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF4057525.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITTEFKEKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKSRRISFYVLHSPLDNYSYYSTSVSFAKALGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMSMVNYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT          463 a          189 c          119 g          456 t
ORIGIN      
        1 ataaatattt ataataatct aaaataaata tttataaatt ctaatcaatc ataaataata
       61 atctaaaata tatcaaaaaa taaacttaaa aacctcgaaa aagaacttaa aagacatcaa
      121 aactaaagct tctaatcagc aattaaaagt ctattttctt agttaaaaaa ataaagatag
      181 attttttcaa aacattggat aaatgggtaa aaaaaataaa cagtcagtaa aacaaatttt
      241 taccaactgt ttctctttat tatttaatat atcctataaa tcctccaagt aatactttcc
      301 ttgtaaaaat tctgactcta aacctagatt tttaaaataa ttgaccatgc tcatacatgc
      361 aaatttttct gtagaatagt gagttgcacc tataacatta attaaattat cttttgctat
      421 ttgatgaaac tctaacactg gttcaaaatg ttttaaaggt ttagtaaatc cagtaatata
      481 taggtttata ccaagttcag caacttctct tgctacaaat ggataacttc ctccccctgc
      541 tgcaatagca actaaaccat cttttaatac agaatctcca taatcataca atttaacatc
      601 atgaccaaca gattttttaa ttaattcctt aatctcttct attgatttta gtgatgtctt
      661 acatataact cctacctcaa ttttatcgtc atatttgcaa aatggtttga ctatttctaa
      721 acctagggct tttgcaaaac taacagaagt tgaatagtaa ctatagttgt ctagtggaga
      781 atgtaataca taaaaagaaa ttctacgact tttcatctct tccatataag atagtggtat
      841 gtcgtgaaat ggaaaacctt catctgatgc tatgtatccc attgcatgat gtgaaaaaat
      901 taaaatatct ttttcatctt tatctataac ctgtttaatt atctctttat caggaaaagt
      961 cgttgtgtat actttattaa tattttgagc attatctaat actaatccta tgtacttttc
     1021 tttaaattct gtagtgataa aatcattttc gaaattcata aaactccaat catcattaat
     1081 atttttaata ttaaattcta agtctaattt tttataaagt tctattgcct tgataataac
     1141 cactccttta taacaacaat tgattaatac attactaata taggaatttc aggataataa
     1201 actttatata tttaagtatt tctactt
//
LOCUS       DAMKOJ010000204         1200 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.214, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000204 DAMKOJ010000000
VERSION     DAMKOJ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1200
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.214"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            66..1106
                     /locus_tag="PC592_003609"
     CDS             66..1106
                     /locus_tag="PC592_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDF4057526.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLECKKDFEDLGLDTL
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAMVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVVTRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFETTESGFIKSRYIDNKSAVAMVLEICRYFKENNLAPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VNVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT          457 a          148 c          204 g          391 t
ORIGIN      
        1 agttttcaga acatttgtat ttatgttata atttgtataa atatatttat ttaggaggaa
       61 acaatatgaa tttaaattta actaatacta taaatttaat gaaaaaatat ttggacattc
      121 caagcccagc tggatatact gaaaatgcag ttttagaatg caaaaaagat tttgaagatt
      181 taggtcttga cactcttctt acaaaaaaag gtgcacttat agccactctt cctggtgaag
      241 atgattcaaa tcaaataaca atatctgcac atatggatac acttggagct atggtaaaag
      301 aaatatcctc tgatggtact cttaaatacc ataaagttgg tggtggatgt tgggctgcta
      361 tagaaggaga aaactgtacg gttgtaacta gaaaaggtaa aaaaatcaga ggaagtgttg
      421 tatttaagta tgcttctact catatatatg gtcaaaccaa agccgctact gaaagaaatg
      481 aagaaacaat gattattaga cttgatgaaa aagtatttac aaagcaagat gtattagact
      541 taggaataag tgttggggat tttgtatgtc tagaccatcg atttgagact acagaatctg
      601 gttttataaa atctagatat atagataata aatcagctgt agcaatggtt cttgaaatat
      661 gtagatattt taaagaaaat aatttagcac ctaagcatac tactaacttt tatataagca
      721 attatgaaga aattggacat ggtgtttcta aatgtttacc tgaaaaaaca aaagaatttg
      781 tagcaataga tatagcacct actggaccaa gtcagacatc tagtgaacat ggtgtaacta
      841 tagttgcaaa ggataattta tcattatatg attttaactt aagaaacaag cttgtgaatg
      901 ttgcagagga caataattta gactacgctg tcgatgtatt tactttctat ggttcagatg
      961 cttcagaagc tattcgttgg ggagaagatg ttcaaatagc atgtgttggt cctggaacaa
     1021 acaatagtca ccattatgaa agaacacata tagaagctat tgaaaataca ctaaaattac
     1081 ttataaatta tatgcttaaa gaataattaa atatatattt taccaaagtc aattcttaac
     1141 aaataactag ctttaatttt tatttttata caaaaattgg tttttctata gacttaattt
//
LOCUS       DAMKOJ010000205         1049 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.216, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000205 DAMKOJ010000000
VERSION     DAMKOJ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.216"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            163..867
                     /gene="cwlD"
                     /locus_tag="PC592_003610"
     CDS             163..867
                     /gene="cwlD"
                     /locus_tag="PC592_003610"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HDF4057527.1"
                     /translation="MRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTII
                     LDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEEN
                     NKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKELS
                     KCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKESKLLTDETYQ
                     EKIAWAIYIGIQKYLS"
BASE COUNT          456 a          101 c          173 g          319 t
ORIGIN      
        1 atatagtgag ttaaagaggg gtagggacat agtatcatta cataataatg tattaatact
       61 aataaataga tatatataaa tattaaaaga aaatttaaat gtttgtacta atatttggaa
      121 tattatagtg tttttataag tatacatata cagggtgatg ttgtgagaaa gtacataaaa
      181 catataattt ttagttttgc aatgatatgt ctagtagtag tatccatatt tgaaattaaa
      241 aatatttctg aagatgttat caagtatatg ccagtaacaa acaaaactat aattctcgat
      301 gctggtcatg gaggtattga tccaggcgca ttaaataagg ataagagtac atctgaaaag
      361 gatatcaacc tagcaataac acttaagctt agagagctta tagaatcaag tggtggtctt
      421 gtaatattaa ctcgagagga tgacagtagc ctttataaag aagaaaataa taaaactaca
      481 agacaaaaat ataatgagaa tttgaagaat agaaaagaaa taatatctaa ttctaatgca
      541 aatatgtttg tctctataca tcttaatgca tttgagcaat caaaatacta tggagctcaa
      601 actttttatc ctaaagataa gcaagatagt aaagaattat cgaagtgtat tcaagaagaa
      661 cttaaaagag tggtagataa aacaaacaat agagaagtca aaccgaggga tgatatatat
      721 cttttgaaag aaaataatat tccatcagta ttgatagaat gtggtttttt atcaaatgaa
      781 aaagagagta aacttttaac tgatgaaaca tatcaagaaa aaatagcatg ggcaatttac
      841 ataggaatac aaaaatattt aagttgaaat aactataaaa ataggtctaa atatgtaaat
      901 agcttgtatt aaagcagtta aaatgcatta atataggcta tttttatttt gacaaaaaaa
      961 tatttaaaat aaaagttaaa aaatagttga cttagaatgg tatagatgat attatatatg
     1021 agtgcccaaa aggagcacca aaataagac
//
LOCUS       DAMKOJ010000206          981 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.217, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000206 DAMKOJ010000000
VERSION     DAMKOJ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.217"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            145..486
                     /locus_tag="PC592_003611"
     CDS             145..486
                     /locus_tag="PC592_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057528.1"
                     /translation="MLNKKNVSLIALVIILSLFTVIFVFNNRNTNDKLKEVTKNNEEI
                     VPKNLEDLSIKQLTEIRDKAIDKNLEGLREFGEDIVKKRKDLILNFEFGLVAFVNKNY
                     SNLTEKEKLIR"
     gene            526..870
                     /locus_tag="PC592_003612"
     CDS             526..870
                     /locus_tag="PC592_003612"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057529.1"
                     /translation="MDPSGSFFELANQSYEINEFMLKNKKNYKEWSYEYIEFLIDHLE
                     ELCKFVDFDVKDVIDIIDPTIKTDLSDEQQKSLNDKLKKMSSSETLNEKIKKEIKNWE
                     NNLNSLNMNKNW"
BASE COUNT          444 a           76 c          134 g          327 t
ORIGIN      
        1 attagtttat cattcgttat aattatataa actatatcaa aaaagtgtta tattgtagtc
       61 tttataataa gcagtaataa aggttactct aataaactga attatttttt acaaacaaaa
      121 tgcttattaa aaaggaggtt taatatgtta aataaaaaaa atgtaagttt aattgcttta
      181 gtaataattt taagtctatt tactgttata tttgttttca ataatagaaa tacaaatgat
      241 aaattaaaag aagttactaa gaataatgaa gaaatagttc ctaaaaactt agaagattta
      301 agcataaaac aattaacaga aattagggat aaggctattg ataaaaactt agaaggactt
      361 agagagtttg gagaagatat agtaaaaaaa cgtaaagatt taattttaaa ttttgaattt
      421 ggattagttg cttttgttaa caagaattat agtaacttaa cagaaaaaga gaaattaata
      481 agataaatta atattgttaa ctatgaaagc tctataaatg aaataatgga tccttcaggt
      541 tcattctttg aattagcaaa tcaaagttat gaaattaatg agttcatgtt aaaaaacaaa
      601 aaaaattata aagaatggtc atatgaatat atagaattcc taattgatca tttagaagaa
      661 ttgtgcaaat ttgttgattt cgatgtaaaa gatgtaatag atattattga tcctacaata
      721 aaaacagatc tttcagatga acaacagaaa tccttgaatg ataaattaaa gaaaatgtct
      781 tcaagtgaaa ctttaaatga aaaaattaaa aaggagataa aaaattggga aaacaattta
      841 aatagtttaa atatgaacaa aaattggtaa tatctcaaaa taagtctgga aatatttatg
      901 tgtattcttt aactaaaaat ttatttttta atagaaataa agcaagatta aaagttgcaa
      961 gacttcaaga acatatagct a
//
LOCUS       DAMKOJ010000207          915 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.218, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000207 DAMKOJ010000000
VERSION     DAMKOJ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.218"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(521..697)
                     /locus_tag="PC592_003613"
     CDS             complement(521..697)
                     /locus_tag="PC592_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057530.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     ICLYQVLLLVSRYN"
BASE COUNT          372 a           89 c          100 g          354 t
ORIGIN      
        1 aaataaaata aattaatcaa tatagttttg taatataaac aaaacataaa aaatatatat
       61 aaataaaatg attgtttttc ttgcaatatt tatataaata ttgaaatttg tctagttata
      121 cgtttttatt gaccagttac gcagttgata ttgaatattc taaatattga tgttatttta
      181 tagatggttt aaacatacta gggggatttt ataaatgtta tttgtatgct ttatagaaaa
      241 tgtataaaat ggtaaaaatt tagagatata tttgatgaaa ttacagaata tgtgtataga
      301 atgatgctca tacattaatt tagatataag gaatgtataa tttgtattga atgatttatt
      361 tttatgtgta tatttttgac tgttttaatg aaaaagtaaa gatgtactcc caatacatct
      421 ttactttagc agaagttata gttacttata aagtacaaaa aaattatata tttattaagg
      481 taggtaaatc taaaagggtt ttcctaggaa aaacttaatt ttaattatat cgactcacta
      541 ataataaaac ttgatacaag catatttcaa ctacagtttc tccgtattct gatataaaat
      601 catctaactg tgtatctaaa aaattacaat aatcatatga actgcttata taagcagtta
      661 atatatgtgt acatttgtct atttctccaa taaacatatt attcatcccc ctaaaaaatt
      721 tagtaaaagt aaaaattata ttttaaaaac aaaataacaa aacttataaa attttttagt
      781 actagttact ataactctat aaaactaaat attcctagtt ttaccaattt agttttattc
      841 tacaaatata taatactaga agatgcttca ttattcaaca tgcttgtttg aaaatgaaaa
      901 atattatgaa attat
//
LOCUS       DAMKOJ010000208          910 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.219, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000208 DAMKOJ010000000
VERSION     DAMKOJ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.219"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            163..669
                     /locus_tag="PC592_003614"
     CDS             163..669
                     /locus_tag="PC592_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HDF4057531.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          369 a           82 c          146 g          313 t
ORIGIN      
        1 tataaaatat aaaaactact tattgcgaaa gtaattgatt tgttgtatta taatttacat
       61 gaattatgta agacaatcaa aattcagtat tataagagta catatattca aatttttaac
      121 aattaattta tataattaaa aaatgaaggg taggatgaag tcatgggttt tagagaagta
      181 aaaattgagg aactacagtt taatccattt actaagattg gcaaagaatg gttacttata
      241 acagctggtg attcagaaaa gtttaacaca atgactgcta gctggggtgg tgttggagta
      301 tattggggta aaaatgttgt tacaacttac ataagaccac agagatatac aaaagaattt
      361 gtagatagta atgatacatt tacagttgcc ttctttgatg aaacgtatag agaagcttta
      421 aatatttgtg gtactatttc tggtagagat ataaataaaa tagaaaaagc aggacttaca
      481 ccatattttg tggatgacac agtagctttt gaagaagcta atatgattat agtatgtaaa
      541 aagttatatc atggtaatat gccaccagaa aactttgatg ctaaagaaaa tgataaaaaa
      601 tggtatccag agaaagacta tcatactatg tacatttcag aaattataaa agttcttgta
      661 aaagaataat tataataaaa agtatctaaa aagaacttat tataagtaaa tgattgtact
      721 ttcttatctt atatttaagt agatgctaat aagtaaataa atattaattt taaataaata
      781 ctattataaa aaagatgaac tatatttgct agagttcatc tttttattta tgtaagcact
      841 tatataagta gagatttact tgagtaaaag tatttatttg agatatttga gtacacttta
      901 taagtatttt
//
LOCUS       DAMKOJ010000209          877 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.220, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000209 DAMKOJ010000000
VERSION     DAMKOJ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.220"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(184..>877)
                     /locus_tag="PC592_003615"
     CDS             complement(184..>877)
                     /locus_tag="PC592_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4057532.1"
                     /translation="GYSDVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYD
                     LSTVELISHPNCFIPKKHGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIP
                     SINNFEKRAKIGKCKIGDLWEDDYVLDDSAIICKTGKGIFIVTGCSHSGICNIVEYAK
                     KVCGDDRVIGILGGFHLFELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILN
                     VNEVGVGLTISI"
BASE COUNT          324 a          158 c           70 g          325 t
ORIGIN      
        1 acattattaa tacataataa aattgtttat tgatgaaaat atattcttat taaaaataaa
       61 ttttttcaca atatttcata taaaagtaca ttgatttctc ttaaaataaa cataataaaa
      121 aagatacttt ctatagaaaa tatcttttta accttcaact taaatcttat atactttcaa
      181 atactatatg cttatagtca atcctacccc tacttcattt acattcaata tttcattcat
      241 cttagctttt accttaaaag aaacacaatg acaagggtac aacattctta tttcttcttt
      301 atccaaatat tgtattgtgc tatccagcct attattcaat tcaaaaagat gaaaaccacc
      361 cagtatacca ataactctat catctccaca taccttttta gcatactcta ctatattaca
      421 aattccacta tgagaacatc ctgtaacaat aaaaatacct ttaccagttt tacaaattat
      481 agcagagtca tctaaaacat aatcatcttc ccacaaatct cctattttac atttaccaat
      541 tttagctctt ttttcaaaat tatttataga aggtatttca cctaaaaaca cacaattctt
      601 acttagatta aatggcttat ccttaggatt atacataaaa atatttttaa tttcctcagc
      661 agaaaatgga gctcctatgc ttttctctcc atgtttttta ggtataaaac agttaggatg
      721 tgaaataagt tcaactgtag acaaatcata tctattttct aaaaactgta tacctcttgt
      781 atggtcatta tgaccatgag aaaaaacaac atgtgttaaa tttcctaaat ctatatttaa
      841 tttttcagcg tttgatatga atacatctga atatccc
//
LOCUS       DAMKOJ010000210          867 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.221, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000210 DAMKOJ010000000
VERSION     DAMKOJ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.221"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..332)
                     /locus_tag="PC592_003616"
     CDS             complement(<1..332)
                     /locus_tag="PC592_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4057533.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKERPDADSITLKYKCYDMPLDTTLNYNQSTDSYEGTINYNKDPE
                     YLNVWELQG"
     gene            complement(611..727)
                     /gene="rrf"
                     /locus_tag="PC592_003617"
     rRNA            complement(611..727)
                     /gene="rrf"
                     /locus_tag="PC592_003617"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(736..809)
                     /locus_tag="PC592_003618"
     tRNA            complement(736..809)
                     /locus_tag="PC592_003618"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(775..777),aa:Gly,seq:tcc)
BASE COUNT          307 a          148 c          110 g          302 t
ORIGIN      
        1 ccttgtagtt cccaaacatt tagatattct gggtctttat tataattaat agttccctca
       61 tacgaatcag ttgattgatt gtagtttaga gttgtatcca atggcatatc atagcattta
      121 tattttaatg taatgctatc tgcatcaggc ctttctttaa acttaacact gacttttgaa
      181 gtactaccta aaacgatact ttttttctct aagtttatat ttaaatcagc attattctcc
      241 atagcattag attcagtagc aaatgccatt gtaggtgcga cgattgccat tgaaagaatc
      301 cctgttgtta ataattttgt atttcttctc atattaatct ccttatttaa cataaatttc
      361 tactttattt tttaaccttt taacttttga aaatatatca aagtgtattt acccaaaatt
      421 gtaaataagt acataaaata aaaaataaac ttctaaaaaa attataaaaa caaaaaataa
      481 aaaaattaaa tatattgaat atatttaatt atcttcacta tatcatttat tgccaaaaaa
      541 atctataaaa gacaaataaa aacatataat aattgtaggt ttattaaatt taatacaaca
      601 aaaaaagatt acgtggctac gtcctactct cccaggcagt ttcccaccaa gtaccatcag
      661 cgctagagag cttaacttct gtgttcggaa tgggaacagg tgtatcctct ctgctattgt
      721 aaccacataa tcttttggag cgggtgaagg ggatcgaacc ctcacagctg gcttggaagg
      781 ccagaactct accattgagc tacacccgca ttaaattttt ataattagca aaactaattt
      841 tttagaatta gcactctaaa aactaca
//
LOCUS       DAMKOJ010000211          853 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.222, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000211 DAMKOJ010000000
VERSION     DAMKOJ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..853
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.222"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(349..>853)
                     /locus_tag="PC592_003619"
     CDS             complement(349..>853)
                     /locus_tag="PC592_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF4057534.1"
                     /translation="QNSMKQEPCDFSHGRFRRENNVMAVHCPASNFNVGSGAMPIRKL
                     IDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKLYWVNSGKKYNFLSLSEAFYIATKS
                     GGSFFGKVGSFEEGYDFDALIIDDSDLNHDNYSILERLERFIYVGDDRNIIHRYVCGK
                     LIEEPNI"
BASE COUNT          324 a          127 c           99 g          303 t
ORIGIN      
        1 tatggcacat atgttttgat gatatttatt atttattaaa agaaacaatg aggttaaaat
       61 taatatcata taataaaatt gtattacttt aaaacgattt atcaataggt aaaatttatg
      121 aggtatgaat acaataacaa tatagtttta cgattgtaga tatcaaaaaa tgtatgttac
      181 tagaaaggcg ttttgtagat ttatatatga tgtaatcatt aaagctataa ataaactaaa
      241 taaaaagagt atgttttaac ctacgctttt agatttgaaa tatactcttt tattaattat
      301 agttatacaa attaaccaga ttatatataa ttaaaatttt tataataatt atatattagg
      361 ttcttcaatt agttttccac atacatatct atgaatgata tttctatcat caccaacata
      421 gataaatctt tcaagtcttt caagtataga ataattgtca tgatttaaat ctgaatcatc
      481 aataatcaat gcatcaaaat cataaccttc ctcaaagcta ccaacttttc caaagaaact
      541 tccaccactt ttggttgcaa tataaaaagc ttcagataaa gacaagaaat tgtacttctt
      601 accagagtta acccaatata atttagataa ttgtattgca gataccattg ctttaaatat
      661 tgacaatgta tgcccaccac ttatatctga accaagtgct aatctaatat tattatcgat
      721 taattttctg ataggcatag caccactacc aacattaaag ttagaagctg gacagtgaac
      781 tgccataaca ttgttttctc tcctgaacct cccatgacta aagtcacagg gttcctgctt
      841 catagaattt tgc
//
LOCUS       DAMKOJ010000212          832 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.223, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000212 DAMKOJ010000000
VERSION     DAMKOJ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.223"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            14..104
                     /locus_tag="PC592_003620"
     tRNA            14..104
                     /locus_tag="PC592_003620"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Ser,seq:gct)
     gene            113..189
                     /locus_tag="PC592_003621"
     tRNA            113..189
                     /locus_tag="PC592_003621"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:147..149,aa:Pro,seq:tgg)
     gene            274..349
                     /locus_tag="PC592_003622"
     tRNA            274..349
                     /locus_tag="PC592_003622"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:307..309,aa:Trp,seq:cca)
     gene            410..486
                     /locus_tag="PC592_003623"
     tRNA            410..486
                     /locus_tag="PC592_003623"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Pro,seq:tgg)
     gene            493..569
                     /locus_tag="PC592_003624"
     tRNA            493..569
                     /locus_tag="PC592_003624"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:527..529,aa:Ile,seq:gat)
     gene            573..648
                     /locus_tag="PC592_003625"
     tRNA            573..648
                     /locus_tag="PC592_003625"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:606..608,aa:Phe,seq:gaa)
     gene            656..732
                     /locus_tag="PC592_003626"
     tRNA            656..732
                     /locus_tag="PC592_003626"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:690..692,aa:Met,seq:cat)
BASE COUNT          219 a          182 c          225 g          206 t
ORIGIN      
        1 aataactgaa tttggagaag tactcaagtg gctcaagagg atcccctgct aagggattag
       61 gctgggtaac cggtgcgagg gttcgaatcc ctccttctcc gccattcaaa aacgaggtgt
      121 agcgcagttt ggtagcgcac atggtttggg accatggggc cgggggttcg agtcccttca
      181 cctcgaccaa cttagctttt agttcggttg gttagagtgc ccaactcata accagagatt
      241 ctggggattg agtccatgaa ggttattctt cataggggtg tagctcagtt ggtagagcgt
      301 cggtctccaa aaccgtgcgc cgggggttcg agtccctcca cccctgccaa ataaaaagga
      361 cttgaaaaaa gttgggtttt agagtagtat aagatagtaa ataagatttc gaggtgtagc
      421 gcagtttggt agcgcacatg gtttgggacc atggggccgg gggttcgagt cccttcacct
      481 cgaccaagaa aagggcctat agctcaggtg gttagagcgc acgcctgata agcgtgaggt
      541 cgctggttcg agtccagcta ggcccaccat ttgcccagat agctcagtcg gtagagcagg
      601 ggactgaaaa tccccgtgtc ggtggttcga ttccgcctct gggcaccaga aatacggcgg
      661 tatagcttag ttggctagag cgttcggttc atacccgaaa ggtcataggt tcgactccta
      721 ttaccgctac catctaacta tatcaataaa gaactttgaa aattaaacag taggttaatt
      781 tataaacaag aaacaaacca taaagccaga tattttgata acaatagtat ct
//
LOCUS       DAMKOJ010000213          814 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.224, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000213 DAMKOJ010000000
VERSION     DAMKOJ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.224"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            61..483
                     /locus_tag="PC592_003627"
     CDS             61..483
                     /locus_tag="PC592_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDF4057535.1"
                     /translation="MNTFKIEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESIITRYELIHIDLENTKLIFTENMSERNVF
                     GKINSVLVRILFGKRQPEEFNKFIKNLEMELENNSVNL"
BASE COUNT          363 a           76 c           94 g          281 t
ORIGIN      
        1 actattttaa cttaaaaatt aacttataaa attaaattta tatacaggag gaaaaacgat
       61 atgaatacat ttaaaattga agttttatta aaatattctg caaaagacat atttaatata
      121 tttacaaaat ctgcaagact aaattttcct aattttaatg agaaaaaagc agtgggcaca
      181 tttgtacaac aaaaaaataa taaaagattt aaggttgaaa taactaattt cgaaaaaaat
      241 agagtatatg agataaaaac aagcaataaa agagaaagta ttattactag gtatgaattg
      301 atacatattg atttagaaaa tacaaaactt atttttactg aaaatatgag cgagagaaat
      361 gtatttggaa aaatcaattc agttcttgta agaatattgt ttggaaaaag gcaaccagaa
      421 gaatttaata aatttataaa aaacctagaa atggagttgg aaaataatag tgttaattta
      481 tagatataag ttacattata ttatatttaa aaactgtcta gaaacatatt tttaagtatt
      541 tttgggatac tgctatttgt tacaataatt acttaaaaaa ctattgatag tcatataaca
      601 ccatgactat ataccacatt aggagtttca ttagtaataa taattttatg tattattgct
      661 tttagttaaa aaaagaaaaa aattaataat ctccaataca tcttaaactt ccaataaata
      721 ggataatctt tatctaataa gattatccta ttctaactta gaacagatat taatttattc
      781 actaaaaaat atatgttata ttcttatatc tagt
//
LOCUS       DAMKOJ010000214          813 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.225, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000214 DAMKOJ010000000
VERSION     DAMKOJ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.225"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            100..216
                     /gene="rrf"
                     /locus_tag="PC592_003628"
     rRNA            100..216
                     /gene="rrf"
                     /locus_tag="PC592_003628"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            223..297
                     /locus_tag="PC592_003629"
     tRNA            223..297
                     /locus_tag="PC592_003629"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:255..257,aa:Asn,seq:gtt)
     gene            302..376
                     /locus_tag="PC592_003630"
     tRNA            302..376
                     /locus_tag="PC592_003630"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:335..337,aa:Glu,seq:ttc)
     gene            382..457
                     /locus_tag="PC592_003631"
     tRNA            382..457
                     /locus_tag="PC592_003631"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:415..417,aa:Val,seq:tac)
     gene            463..539
                     /locus_tag="PC592_003632"
     tRNA            463..539
                     /locus_tag="PC592_003632"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:497..499,aa:Asp,seq:gtc)
     gene            551..625
                     /locus_tag="PC592_003633"
     tRNA            551..625
                     /locus_tag="PC592_003633"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:583..585,aa:Thr,seq:tgt)
     gene            639..723
                     /locus_tag="PC592_003634"
     tRNA            639..723
                     /locus_tag="PC592_003634"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:673..675,aa:Tyr,seq:gta)
     gene            733..806
                     /locus_tag="PC592_003635"
     tRNA            733..806
                     /locus_tag="PC592_003635"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:765..767,aa:Gly,seq:tcc)
BASE COUNT          220 a          186 c          208 g          199 t
ORIGIN      
        1 tgtagttttt agagtgttaa ctctaaaaaa ttaaaaaaag tattgacaaa aaaagtaaaa
       61 aatgttaata ttatacttgt cctagcaaca agacaaaaat gtggttataa tagcagagaa
      121 gatacacctg ttcccattcc gaacacagaa gttaagttct ctagcgctga tggtacttgg
      181 tgggaaactg cctgggagag taggacatag ccacgtaaat gttccaaggt agctcaacgg
      241 tggagcaacc ggctgttaac cggtaggctg tgggttcgag ccccaccctt ggagccatta
      301 aggctcgttg gtcaagaggt taagacaccg ccctttcacg gcggtaacag gggttcaatt
      361 cccctacgag tcaccatttg tgggatcata gctcagctgg gagagcacct gccttacaag
      421 cagggggtca caggttcgag ccctgttggt cccaccattt gcggcctggt agttcagttg
      481 gttagaatgc cagcctgtca cgctggaggt cgagggttcg aaccccttcc aggtcgccaa
      541 aataaaaaat gctggtgtgg ctcaacggta gagcagctga cttgtaatca gcaggttgta
      601 ggttcgattc ctatcaccag ctccatgtaa attaatacgg aggatttccc gagcggccaa
      661 agggggcaga ctgtaaatct gttgtcatcg acttcggtgg ttcgaatcca ccatcctcca
      721 ccaattaaat atgcgggtgt agctcaatgg tagagttctg gccttccaag ccagctgtga
      781 gggttcgatc cccttcaccc gctccaaaga aag
//
LOCUS       DAMKOJ010000215          797 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.226, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000215 DAMKOJ010000000
VERSION     DAMKOJ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.226"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
BASE COUNT          306 a           73 c           94 g          324 t
ORIGIN      
        1 gaaatataat ttttataact ctactaattt taaacatttt taaataaata tttgtatata
       61 ccttatataa tattatagta attagtttta aatcaataga atagtatgta tttatctaat
      121 gcggcaatat aatttaaagc tggtgttgta gaaaaactaa gagtgaatat agcaaagaga
      181 agcaatagta ttttaaactt tgtctctctt attttttgaa aactaacatt aaaacataag
      241 gtataaataa tattatcata taaatgaaaa caaatttgaa tttttctctg gtcgatgtat
      301 atagtaagtt tgttgatagg agaaaaatta ttattgataa tatacatgca tagaaaggaa
      361 atggtatata atattttctt aagtttcttt tttaggcatt tctattggca ttttaggcta
      421 tagtactaaa tacattaacc aacaaaataa tgaaataaat atatatatag aaaacttaat
      481 tttcgtggga agaaaaaaag caataatagc aagtattatt agagaataac gaataatacg
      541 agtaacattt ctttcttttt ctatgatagt taaatcccag tgatttttta taaattcaag
      601 gtctttttct tgactctgat tcatttaatc atttcctgtt aatagtataa ttttaaagct
      661 attactttgt tttattttaa catatttata cactaaagtg aattttatga ttagatttat
      721 ttaattattt ctgaattaaa acttattaga attctctatt ttgataattt caaactctat
      781 tgattgtatg ataattg
//
LOCUS       DAMKOJ010000216          736 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.227, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000216 DAMKOJ010000000
VERSION     DAMKOJ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.227"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>736
                     /locus_tag="PC592_003636"
     CDS             <1..>736
                     /locus_tag="PC592_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4057536.1"
                     /translation="LSLSMITILASVGEVNALEVKNNSNLEKQTIKETVVPELVGLKM
                     QEAFPDENFRKYIFGILVTLDISDIRDDTTINSEIKQKIEGIKDLSLEYESIKDLTGI
                     NYFTGLEKLYCSSNELKKLDLSKNTKLEELNASSNKLKTINLNGSEKLKTLLCNDNEL
                     SNLDVSKNTKLKYLYCDNNRLEKLDITNNKNLVGYSWGNQKEPEKPSEPEKPSGGGSY
                     TPAPIVTKINSLVGSDRYATSIKISKQ"
BASE COUNT          325 a           79 c          113 g          219 t
ORIGIN      
        1 tttatcatta tctatgataa caattttggc ttcagtagga gaagtaaatg cactagaagt
       61 caaaaataat agcaatttag aaaaacaaac aataaaggag actgttgtac ctgagttagt
      121 aggattaaaa atgcaagaag cttttccaga tgaaaatttt agaaaataca tttttggtat
      181 tttagtaact ttggatattt cagatattag agatgatact actataaata gcgaaataaa
      241 acagaaaatt gaaggaataa aagacttaag tttagagtat gaatctataa aagatttaac
      301 aggaattaat tattttactg gattagaaaa attatattgt tcttctaatg aactaaagaa
      361 attagattta agtaaaaata ctaaattaga agagttaaac gctagttcta ataaattaaa
      421 aacaataaat ttaaatggaa gtgaaaaact taaaacttta ttgtgtaacg ataatgaact
      481 aagcaatcta gatgtaagta aaaatacaaa acttaaatat ttatattgtg ataacaatag
      541 actagaaaaa ttagatatta ctaacaataa aaatcttgta ggttactctt ggggaaacca
      601 gaaagagcca gaaaaaccat ctgagccaga gaaaccgtct ggaggaggtt cttatactcc
      661 agctccaata gttacaaaaa taaattcttt agtaggttct gatagatatg ctacctcaat
      721 aaaaataagt aaacaa
//
LOCUS       DAMKOJ010000217          734 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.228, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000217 DAMKOJ010000000
VERSION     DAMKOJ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.228"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(75..560)
                     /locus_tag="PC592_003637"
     CDS             complement(75..560)
                     /locus_tag="PC592_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF4057537.1"
                     /translation="MISELMLKNFGESSINFKTKIKLNLREKPDLNSLKLKSIPGGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNDSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKIITTIPDGFKVEVCYNVGKWARVNIDKNEKRYSGYVYNQYIEEYLG
                     L"
     regulatory      complement(643..734)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT          236 a          123 c           57 g          318 t
ORIGIN      
        1 gacaaaaaaa gaaccccttt aaagggattc ttttttgtaa tttattaata tatttaaagc
       61 tcactagtat catattataa acctaaatat tcttctatgt attgattata tacatatcca
      121 gaatatcgtt tttcattttt atcaatatta actcttgccc atttcccaac gttataacat
      181 acttcaactt taaaaccatc aggaattgta gttataattt tagattctaa tgttctatca
      241 tttctaagtt ctaaacttaa tccatttgtt cttatatttc ctatataatt cttttttcta
      301 ttttttattg tatcattact atcattttta gcattactta atctttctaa atatttataa
      361 agtaaccagc ctttgtcata attactctca acttctgccc atattccatc tacacatttt
      421 aacttaacaa ttttaccccc tggtatactt tttaatttta aactatttag gtctggtttt
      481 tctcttaaat tcaatttaat tttagtctta aaattgatgc tagattctcc aaaatttttt
      541 aacattaatt cagatatcat cttaagccct cctcttgcca aatattaagt tattaaaata
      601 tataactcta aaaatatttt taacaaaaag aatcattatc tttttggcaa ctggctgaca
      661 tgacctttat tatataaaga ttttagtccc tatagttttg cgtcattaga tttatctaat
      721 attgcctata tatg
//
LOCUS       DAMKOJ010000218          676 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.229, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000218 DAMKOJ010000000
VERSION     DAMKOJ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..676
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.229"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            13..672
                     /locus_tag="PC592_003638"
     CDS             13..672
                     /locus_tag="PC592_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF4057538.1"
                     /translation="MLDTFITIVSSIIEIWSCKKVFDYTSQTKTDLKKLNMYFFFSVF
                     LIISFLYINIGANSRILICIFVMFIFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKLILGILLYIYKISFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYILNLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
BASE COUNT          249 a           57 c           85 g          285 t
ORIGIN      
        1 gaggatatta ttatgctaga cacatttata acaattgttt cttctattat agaaatatgg
       61 tcatgtaaaa aagtttttga ttatacgagt cagacaaaga ctgacttaaa aaaactaaat
      121 atgtatttct tcttttctgt ttttcttatt atttcttttt tatatataaa tataggagct
      181 aatagtagaa tcttgatatg tatatttgta atgttcattt tctataagtc taactataaa
      241 gttaatatat ataaatgtct agtgatatca tttttttatt ggttaatatt aataggtata
      301 aatggattaa gtatgttatt agtagcaaca gtaagtaatt tggataatat gaatgtttta
      361 cttagtggaa gtttatatag atatgaagca atattcttgg gaaagttaat attaggtatc
      421 ttgctgtata tttataaaat ttcttttaaa aattttaaaa taagtaaaaa agagatatac
      481 atatgtattc ctatgatagc aaatctattg tcattttttg tactttatga ttatattctt
      541 aatctcgtaa aaatttctcc tgaaagaaga actgcttttt tagtaatagt tttactatta
      601 atattatcta acatttcaat ctttgtatta atacatataa tacttaagat taaaattagg
      661 aaaataagat aaatct
//
LOCUS       DAMKOJ010000219          655 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.230, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000219 DAMKOJ010000000
VERSION     DAMKOJ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.230"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..>655)
                     /locus_tag="PC592_003639"
     rRNA            complement(<1..>655)
                     /locus_tag="PC592_003639"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          143 a          205 c          149 g          158 t
ORIGIN      
        1 agttggcttc gcgcttagat gctttcagcg cttatccatt ccgtacatag ctacccagcc
       61 atgcccttgg cagaacaact ggtacaccag aggtacgtcc atcccggtcc tctcgtacta
      121 aggacaggtc ttctcaaatt tcctacgcct gcgacggata gggaccgaac tgtctcacga
      181 cgttctgaac ccagctcgcg taccacttta atgggcgaac agcccaaccc ttgggaccta
      241 ctacagcccc aggatgtgat gagccgacat cgaggtgcca aacctccccg tcgatgtgga
      301 ctcttggggg agataagcct gttatcccca gggtagcttt tatccgttga gcgatggccc
      361 ttccacgcag aaccaccgga tcactaagtc cgattttcat ccttgctcga cctgtatgtc
      421 ttgcaatcaa gctctctttt gcctttacac tctacgtacg atttccgacc gtactgagag
      481 aacctttgag cgcctccgtt accttttggg aggcgaccgc cccagtcaaa ctgcccacct
      541 gacagtgtcc caagaccaga ttcatggcct atggttagag tcccagtact acaagggtgg
      601 tatcccaagg atggctccgc caaaactggc gtcctggttt caaagcctcc cacct
//
LOCUS       DAMKOJ010000220          621 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.231, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000220 DAMKOJ010000000
VERSION     DAMKOJ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.231"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(115..594)
                     /locus_tag="PC592_003640"
     CDS             complement(115..594)
                     /locus_tag="PC592_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF4057539.1"
                     /translation="MSNKIIKNLLSGILQILFFLLGLVIVVGGFKSFIYLCFSGEATL
                     QGTISGILMFILGVSYFIIIKLLIEVLGSSEYSLFVKENVKRFRVIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVLVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT          244 a          103 c           44 g          230 t
ORIGIN      
        1 ctttttcatt ttagcattat agtttatgca ttatacttta atatatttta ttttaaatta
       61 ctagttaacc tctcttttca agttatctat cttctatata ttaaagtata gttcctaaat
      121 agttaaatca ttatcctctt ttatctttat tgcctttaca aatccatctg caattacaaa
      181 actcataaga gaagttataa aatatacaag tactggaaca gtaaaataaa atccaaatcc
      241 taaatctagg aatctcattc cttttccagt agtaccaaaa gttgaaataa actcaattag
      301 agagtttaaa agcaaaagat atccaataac cctaaatctt tttacattct cttttacaaa
      361 taggctatat tcagaactac ctaatacttc tatcaataat tttataataa taaaatatga
      421 tacacctaaa ataaacatta atattccaga aatagtgcct tgtagagttg cttctccact
      481 aaaacatagg tatataaaac ttttaaatcc tcccacaact attactaatc ctaaaagaaa
      541 aaataaaatt tgtaatatac cacttaataa attttttata attttattag acatcatacc
      601 aactccttta aaatatttta t
//
LOCUS       DAMKOJ010000221          594 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.232, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000221 DAMKOJ010000000
VERSION     DAMKOJ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..594
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.232"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
BASE COUNT          239 a           43 c           76 g          236 t
ORIGIN      
        1 cgctaaagat aagaatgtat aaggtggtaa atttgtataa aaaagaatat gagttgtaaa
       61 atattaaatg atattatact aattggaata attttaactt tattatatat tattttaata
      121 ccattagtac tgatgatgta ttttaagagt ggtataagca ttacaaatac gaatatgcca
      181 actgtaatat aaataatata agtagctata tacatatgtg ctgtcccata tattgtatca
      241 ttgtttatat taaaaagctt atgtaattgg tagcaatcaa taaataattt tcaaaagaaa
      301 tacctaaaaa cttaaaaaat acatatatgt acatttagtt agatttgaga tttttatata
      361 taattttgta gtgacaatat tatatattgt tattatgtct atttatatgc aattactata
      421 atatcagaag ttatagtatt atttgtttca ttatcaatag gattttttac tttagttttg
      481 tcaattttat ttaaaaaaat tattgatata aaagatgaga aggataaaac tacatgatag
      541 atttcaaaca taagagtgga tatttatata atagatattt tattgagtac tgta
//
LOCUS       DAMKOJ010000222          577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.233, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000222 DAMKOJ010000000
VERSION     DAMKOJ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.233"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>577
                     /locus_tag="PC592_003641"
     rRNA            <1..>577
                     /locus_tag="PC592_003641"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAMKOJ010000223          542 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.234, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000223 DAMKOJ010000000
VERSION     DAMKOJ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.234"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            135..416
                     /locus_tag="PC592_003642"
     CDS             135..416
                     /locus_tag="PC592_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057540.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT          248 a           33 c           78 g          183 t
ORIGIN      
        1 atatattaaa gaaaagtaga tataaaacaa aattagaaaa taatagtgtt actttcataa
       61 taaatacata taaagatatt tttaagaata aaatttacta ttaaataaaa aataaaggag
      121 agtgatttaa tagtatggca tcaaaacaaa caccaagaaa caatttggaa aagtttttaa
      181 gaataagagt cttatcacat acaggagata aaatacatat aaagttacct gtaaattttg
      241 caaagagaat gattgagaat aatgctttgg atttatttaa tggaaaagat gatgtagtag
      301 atggtaaaaa agttactgaa atattagtca aagcatttga ctatgattta actggagaag
      361 tagttcactt agagagaaaa aatggagata ttattaaagt ttcaatcgta caatagaatt
      421 attttatatg aattttattt ttaaatagtt ataaataatt agaaatttgt aaaaaagtat
      481 aatatattat tagtaatgat gtagaataca catttataat ttatagatgt gtatttttta
      541 aa
//
LOCUS       DAMKOJ010000224          529 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.235, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000224 DAMKOJ010000000
VERSION     DAMKOJ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.235"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(60..428)
                     /locus_tag="PC592_003643"
     CDS             complement(60..428)
                     /locus_tag="PC592_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF4057541.1"
                     /translation="MTRPSIYNSQGYTCAEALIKSYNEEHNTDIPISIGSGMGFGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELMNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT          158 a           90 c           49 g          232 t
ORIGIN      
        1 ttaaaatatc ataaaaaaaa caagtatttt atcgaatgca aaatacttgt ttcttagaat
       61 tatttttgat tttttagcat atcatttaga gcatcatatg tgaaatttat tatttcttca
      121 caagttactt tatttttttt aagagataca catatttctg agctgtattt atttcttact
      181 ctattcatta attctcttga atacttcctt gctatgtttt catctaaatt actatttcgt
      241 ccatttaaat accctattat aacaactgca gcatttacag ctccacaaac acttccaaca
      301 ttcattccaa accccatgcc acttcctatt gagattggta tatctgtgtt gtgttcctca
      361 ttataagact ttattaatgc ctctgcacaa gtgtatcctt ggctattata tattgatggt
      421 cttgtcattt ttatacttcc tttcaaattt tattttatat gttttactat tttaaatatg
      481 ctaatggtct ctatattata tatactattt ttgtatctat aaaatccaa
//
LOCUS       DAMKOJ010000225          519 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.236, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000225 DAMKOJ010000000
VERSION     DAMKOJ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.236"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            183..>519
                     /locus_tag="PC592_003644"
     CDS             183..>519
                     /locus_tag="PC592_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF4057542.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIY"
BASE COUNT          211 a           42 c           61 g          205 t
ORIGIN      
        1 ataaaaatga tttttatata aattttaaac agaagaataa atttctaacg aaattggata
       61 tttcttctgt aaatacatat tcaaaaaaag aattataaga atttagtcag cagtcgttta
      121 agtaataagg actttataaa tatatagaaa tataatgata tgagtataag tagaaaaatt
      181 ttatgatttt tacaattatt ttttataaaa aagggaggtt atgtttgttg aatttacaat
      241 caaaatgggt aaacttttta aagccaacat atgtcagtga tgaaataaaa agaaaaaaac
      301 tacaagttat aatatttttt tctataactt atggtttatc ttattcacta ggtttattag
      361 caatatgttt taatcattta atagattcag aaattttagc tcaatttatg atgatattac
      421 cattatcttc agtttctatt gcaaaatttt acacagaggg aagaaataat gataaatata
      481 atttttattc atcagtaata ttatttttta ttatttact
//
LOCUS       DAMKOJ010000226          475 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.237, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000226 DAMKOJ010000000
VERSION     DAMKOJ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.237"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>475
                     /locus_tag="PC592_003645"
     CDS             <1..>475
                     /locus_tag="PC592_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4057543.1"
                     /translation="VPELVGLKMQEAFPDENFRKCISDILNIKDSGDTVITDEMKKTI
                     ESTTILYITTESIKDLTGINYFTGLKELHCSSNELKELDVSKNTKLRNLYCDNNRLEK
                     LDITNNKNLVHYSWGNQKEPEKPSGGGSYTPTPIVTKINSLVGSDRYATSIKISKQ"
BASE COUNT          203 a           58 c           72 g          142 t
ORIGIN      
        1 tgtacctgag ttagtaggat taaaaatgca agaagctttt ccagatgaaa attttagaaa
       61 atgtatttct gatattttga atattaaaga tagtggtgat actgttataa ccgacgaaat
      121 gaaaaaaact attgaaagca ctacaatatt atacataacg actgaatcta taaaagattt
      181 aacaggaatt aattatttta ctggactaaa agaattacat tgttcttcta atgaactaaa
      241 ggaattagat gtaagtaaaa atacaaaact tagaaattta tattgtgata acaatagact
      301 agaaaaatta gatattacta acaataaaaa tcttgtacat tactcttggg gaaaccagaa
      361 agagccagag aaaccgtctg gaggaggttc ttatactcca actccaatag ttacaaaaat
      421 aaattcttta gtaggttctg atagatatgc tacctcaata aaaataagta aacaa
//
LOCUS       DAMKOJ010000227          469 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.238, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000227 DAMKOJ010000000
VERSION     DAMKOJ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.238"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
BASE COUNT          194 a           63 c           45 g          167 t
ORIGIN      
        1 cctttgaaaa tattttaaat aaatttttga atttaatttg aaaactcaat tttgatataa
       61 aaaaaccaca cagtatatac aactgtatgg caaaaatacg aataagccac acagtataat
      121 ccatgtggct ctatattatg atgataaaat aaaaacttta acaacaatta ctatagccaa
      181 catagataca atccttaaaa atcataatcc taaggggctt gtatctatgt tatgacaatt
      241 cgtcttaact taggtacaaa ccctaactaa attggctact aaaaaatcgt acttgtttgt
      301 ttaataaagt cttcatattt acctctcctt ttaatttaat aattttgaaa attttgtttt
      361 ccgttttgta tagtaattag tttaatacag taaaaaataa aagtcaacta taaattttga
      421 aaaattatca aattatcaga aaattaagtt taaacaaaaa aatttttat
//
LOCUS       DAMKOJ010000228          455 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.239, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000228 DAMKOJ010000000
VERSION     DAMKOJ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.239"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            150..266
                     /gene="rrf"
                     /locus_tag="PC592_003646"
     rRNA            150..266
                     /gene="rrf"
                     /locus_tag="PC592_003646"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            272..360
                     /locus_tag="PC592_003647"
     tRNA            272..360
                     /locus_tag="PC592_003647"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:306..308,aa:Leu,seq:taa)
     gene            372..448
                     /locus_tag="PC592_003648"
     tRNA            372..448
                     /locus_tag="PC592_003648"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:406..408,aa:Ile,seq:cat)
BASE COUNT          142 a           85 c          104 g          124 t
ORIGIN      
        1 tctatattgt taaacttgtc aaaatttata gatttttaat agttttataa ggcaaaaaat
       61 cgaataaaaa aagtattgac atattaagac aaagatgtta ttataatact tgtcttagaa
      121 aaaaagttaa atgaaaattt agacaataat ctggttataa tagcagagag gatacacctg
      181 ttcccattcc gaacacagaa gttaagctct ctagcgctga tggtacttgg tgggaagctg
      241 cctgggagag taggacatag ccaggtgatg tgccgaagtg gcggaactgg cagacgcaca
      301 ggacttaaaa tcctgcggga cttacctctc gtaccggttc gattccggtc ttcggcacca
      361 caaattattg tgggccatta gctcagttgg ttagagcgcc cggctcataa ccggtaggtc
      421 tggggttcga gtccctgatg gcccaccaca ataat
//
LOCUS       DAMKOJ010000229          412 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.240, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000229 DAMKOJ010000000
VERSION     DAMKOJ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.240"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>412
                     /locus_tag="PC592_003649"
     CDS             <1..>412
                     /locus_tag="PC592_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HDF4057544.1"
                     /translation="GWRIINNKKYYFNPNNAIAATHLYTINNDKYYFSYDGILQNGYI
                     TIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQNKFLTLNGK
                     KYYFDNDSKAVTGWQTIDGKKYYFNLNTAVAVTGW"
BASE COUNT          155 a           53 c           66 g          138 t
ORIGIN      
        1 ggatggagaa ttattaacaa taagaaatat tactttaatc ctaataatgc tattgctgcg
       61 actcatctat acactataaa taacgacaag tattacttta gttatgatgg gattcttcaa
      121 aatggatata ttactattga aagaaataat ttctattttg atgctaataa tgaatctaaa
      181 atggtaacag gagtatttaa aggacctaat ggatttgagt attttgcacc tgctaatact
      241 cataataata acatagaagg tcaggctata gtttaccaga acaaattctt aactttgaat
      301 ggcaaaaaat attattttga taatgactca aaagcagtta ctggatggca aactattgat
      361 ggtaaaaaat attactttaa tcttaacact gctgttgcag ttactggatg gc
//
LOCUS       DAMKOJ010000230          375 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.241, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000230 DAMKOJ010000000
VERSION     DAMKOJ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.241"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>375
                     /locus_tag="PC592_003650"
     CDS             <1..>375
                     /locus_tag="PC592_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057545.1"
                     /translation="VLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQMIKSLGINIG
                     SIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKKFTFIK
                     DTTAIIVGSFIYQFTIYFAMSLG"
BASE COUNT          112 a           54 c           62 g          147 t
ORIGIN      
        1 gttttagcct tagcttttgt attcatctgt aaagtccttt tagacttatt cctaaaaaca
       61 ggtcttggat acactttaaa gggtgttggt gataactctc aaatgattaa gtctctaggt
      121 ataaatatcg gttctataaa aatactagga cttatgattt caaatggact tatagcttta
      181 tctggtagtc ttatggctca gttcttagga ttttcagatg taaatatggg tataggaact
      241 ttagttcttg gaattgcctc tatcataatt ggtattacac tatttaagaa attcactttt
      301 atcaaagata ctactgcaat aattgttggc tcttttatat accaattcac tatatacttt
      361 gcaatgagtt tagga
//
LOCUS       DAMKOJ010000231          365 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.242, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000231 DAMKOJ010000000
VERSION     DAMKOJ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.242"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(86..161)
                     /locus_tag="PC592_003651"
     tRNA            complement(86..161)
                     /locus_tag="PC592_003651"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(126..128),aa:Gln,seq:ttg)
     gene            complement(169..245)
                     /locus_tag="PC592_003652"
     tRNA            complement(169..245)
                     /locus_tag="PC592_003652"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(209..211),aa:Arg,seq:tct)
     gene            complement(274..357)
                     /locus_tag="PC592_003653"
     tRNA            complement(274..357)
                     /locus_tag="PC592_003653"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(321..323),aa:Leu,seq:tag)
BASE COUNT          111 a           87 c           73 g           94 t
ORIGIN      
        1 ttcggatact taaacttatt ctaaaattga atctaactac cttaaaataa aaatagctca
       61 aatatagttt agtaaataca tcatttggct ggggatgcag gactcgaacc tacgcataca
      121 tgagtcaaag tcatgtgcct taccgacttg gctaatcccc aatatatgtg gtgagcgcac
      181 agggattcga accccggaca cacgccttag aagggcgttg ctctatccag ctgagctatg
      241 cacccacaat tatatatgta tatcaaataa aaatggtgcg gatgaaggga gtcgaacccc
      301 cacgccaatg gcgctagatc ctaagtctag tgcgtctgcc aattccgcca catccgcgca
      361 ttttt
//
LOCUS       DAMKOJ010000232          361 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.243, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000232 DAMKOJ010000000
VERSION     DAMKOJ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.243"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>361
                     /locus_tag="PC592_003654"
     CDS             <1..>361
                     /locus_tag="PC592_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4057546.1"
                     /translation="NPKTLNKQDLENMGLNLKDYNVTQECIIEDITSRKDVNKYLRKT
                     SAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILL
                     VEKNNVPNSVKSELKRLN"
BASE COUNT          160 a           43 c           62 g           96 t
ORIGIN      
        1 aatcctaaaa ctttaaataa acaagaccta gaaaacatgg gattaaattt aaaagactat
       61 aatgtaacac aggaatgtat aattgaagat ataacttcta gaaaagatgt aaataaatat
      121 ttgagaaaaa cttctgcgcc tattacagaa cttacaggaa gcgatagata tgaaacagca
      181 gttaaaataa gtaaagaggg ttggaaaaat ggttcagata aggtagttat aataaatgga
      241 gatgtaagta tagatggtat tatatcaact ccactggcaa ctacatataa tgcgccaata
      301 cttttggttg aaaaaaataa tgtgcctaat agtgtaaaat cagaattaaa acgtctaaac
      361 c
//
LOCUS       DAMKOJ010000233          357 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.244, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000233 DAMKOJ010000000
VERSION     DAMKOJ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.244"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            87..>357
                     /locus_tag="PC592_003655"
     CDS             87..>357
                     /locus_tag="PC592_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057547.1"
                     /translation="MNKKKNLIGMAISFLLIISIINPLQVEAETIIESSVYISSIQEN
                     CTYNNTKFKTIKSRSRHKISKSNKSKVKLKKRSIRTKKYGYQTINK"
BASE COUNT          166 a           28 c           48 g          115 t
ORIGIN      
        1 taagaaattt gaaaaaattt atgattttta gttatatatg tatatattat aatgaagtag
       61 ataaaaattt ttataagggg gaaaatatga ataagaagaa aaacttgatt gggatggcta
      121 tatctttttt acttataatc agcatcataa atccattaca agtagaagcg gaaactatta
      181 ttgagtctag tgtctacatt tcttcaatac aagaaaattg tacatataat aatactaaat
      241 ttaaaactat taaatctaga agtagacata aaattagtaa gtctaataaa agtaaagtaa
      301 agttgaaaaa acgaagtata agaactaaaa aatatggata tcaaactata aataaat
//
LOCUS       DAMKOJ010000234          325 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.245, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000234 DAMKOJ010000000
VERSION     DAMKOJ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.245"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..278)
                     /locus_tag="PC592_003656"
     rRNA            complement(<1..278)
                     /locus_tag="PC592_003656"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           78 a           82 c           56 g          109 t
ORIGIN      
        1 tattggtttg ggctaatccg cgttcgctcg ccgctactta cggaatcgaa tttctttctc
       61 ttccttcagg tacttagatg tttcagttcc ctgagttccc ctcattaagc tatgtattca
      121 cttaatgata cttagacatt actctaagtg agtttcctca ttcggaaatc ttcggatcaa
      181 agtttacgtg caactccccg aagcttatcg cagcttatca cgtccttcat cggctcctag
      241 tgccaaggca tccgccctgc acccttaata acttgaccag ttaaaaaggt ttgatagatt
      301 agaagctatc aacttcgata atttt
//
LOCUS       DAMKOJ010000235          322 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.246, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000235 DAMKOJ010000000
VERSION     DAMKOJ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.246"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..320)
                     /locus_tag="PC592_003657"
     CDS             complement(<1..320)
                     /locus_tag="PC592_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057548.1"
                     /translation="MSVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGASIVAF
                     SLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLRIMGK
                     SNIPL"
BASE COUNT          125 a           58 c           52 g           87 t
ORIGIN      
        1 agaggaatat ttgattttcc cattattctt aagttgatag agtataacat tcccatgact
       61 aaaataccag aaagtaagtt agatatctta aacttaatgt gaagaatccc tgtaacaaga
      121 ccagcagtac aaccacataa gatagccatt aaagttgcta ccacaggaga aataccatta
      181 gtaagagaaa atgctacgat agaagcaccc attgtgtagc taccatcagc agacatatct
      241 gggaaatcta ggattttgta agttatataa acccccagtg ccataatcga taaaattaaa
      301 ctttgcgtca ttacagatat aa
//
LOCUS       DAMKOJ010000236          308 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.247, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000236 DAMKOJ010000000
VERSION     DAMKOJ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.247"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            132..239
                     /locus_tag="PC592_003658"
     CDS             132..239
                     /locus_tag="PC592_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF4057549.1"
                     /translation="MRRHLWNPSYFIATVSENTEEQIRKYINNQKKQVK"
     gene            241..>308
                     /locus_tag="PC592_003659"
     CDS             241..>308
                     /locus_tag="PC592_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4057550.1"
                     /translation="MVVVKKAYKFRMYPNKKQQELI"
BASE COUNT          133 a           29 c           55 g           91 t
ORIGIN      
        1 taaatataaa accttcaaaa tacttgtttt aagtaattgc gtattttaat attatgatag
       61 gtgatgaaaa aaggaagtta ctcatggtag gggatatgca tatagtatgt caaatataaa
      121 catccagtat tatgaggaga catctttgga atcctagtta tttcattgct actgtatcag
      181 aaaatacaga ggagcagata agaaaatata ttaataatca gaaaaaacaa gtaaagtgag
      241 gtggtagtag tgaaaaaagc ttataagttt agaatgtatc caaataaaaa acaacaagag
      301 ttaattaa
//
LOCUS       DAMKOJ010000237          295 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.248, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000237 DAMKOJ010000000
VERSION     DAMKOJ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.248"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
BASE COUNT           73 a           68 c           64 g           90 t
ORIGIN      
        1 catataaagc gccgtgttgt aaatcgtagt attgtaaggt tgtttcaccg ttaaaaatcc
       61 tccttctaaa gaaacaaccc acgcttacaa tacttttgct ctatggcaat tatatcataa
      121 gcgtgggcgt gttatcaatg atgggctatc aggttgaagc ggctttttct gcggtatgcc
      181 gcaccacatc tacaatcaga tcaccgaggg gcttcccgcc tgcggcgaag tgttcggaga
      241 tttttatacg gttgttccca catacaaaat actgcgtgcc gttctctgct tgtat
//
LOCUS       DAMKOJ010000238          267 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.249, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000238 DAMKOJ010000000
VERSION     DAMKOJ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.249"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            151..267
                     /gene="rrf"
                     /locus_tag="PC592_003660"
     rRNA            151..267
                     /gene="rrf"
                     /locus_tag="PC592_003660"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT           93 a           38 c           50 g           86 t
ORIGIN      
        1 tgcagctttt agagtgttaa ctctatgtaa ggtactaact tcaattaatg tagtatatat
       61 cataaaaaca attattattt agtactttaa aactattgac atttaaaaat aaagatgtta
      121 atataatact tgtcttataa ataggcaata tgtggttata atagcaaaga ggatacacct
      181 gttcccattc cgaacacaga agttaagctc tttagcgctg atggtacttg gtgggaaact
      241 gcctgggaga gtaggacgta gccacgt
//
LOCUS       DAMKOJ010000239          259 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.250, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000239 DAMKOJ010000000
VERSION     DAMKOJ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.250"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>259
                     /gene="tuf"
                     /locus_tag="PC592_003661"
     CDS             <1..>259
                     /gene="tuf"
                     /locus_tag="PC592_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005791980.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF4057551.1"
                     /translation="TKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGACKLPE
                     GIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGV"
BASE COUNT          105 a           33 c           61 g           60 t
ORIGIN      
        1 acaaagttta cagcagaagt atatgtactt aaaaaagaag aaggtggaag acatacacca
       61 ttctttgatg gatatagacc acaattttac ttcagaacaa cagacgtaac aggagcttgt
      121 aagttaccag aaggaataga gatggtaatg cctggagata acgtaacaat ggaagtagac
      181 ttaataaact caatagttgt agaagaggga ttaagattct caataagaga aggtggaaga
      241 acagtagctt caggagttg
//
LOCUS       DAMKOJ010000240          249 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.251, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000240 DAMKOJ010000000
VERSION     DAMKOJ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..249
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.251"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(<1..>249)
                     /locus_tag="PC592_003662"
     rRNA            complement(<1..>249)
                     /locus_tag="PC592_003662"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           57 a           72 c           56 g           64 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaa
//
LOCUS       DAMKOJ010000241          241 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.252, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000241 DAMKOJ010000000
VERSION     DAMKOJ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.252"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..>241
                     /locus_tag="PC592_003663"
     CDS             <1..>241
                     /locus_tag="PC592_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF4057552.1"
                     /translation="VLINNSSIADALSATPFAKVKNAPILLTQNNSLNQLTENEISRL
                     GAKNIYIIGGFNSIDESIENYLKDKGLNTIRISGN"
BASE COUNT          108 a           25 c           34 g           74 t
ORIGIN      
        1 tagtacttat aaataattct agtatagcag atgcattatc agctacacca tttgctaaag
       61 ttaaaaatgc accaatatta cttactcaaa ataatagttt gaatcaattg acagaaaatg
      121 aaataagtag attaggtgca aaaaacatat acataattgg tggatttaat tctatagatg
      181 aaagtattga aaattatcta aaagataaag gtttaaatac aataagaata tctggaaatg
      241 a
//
LOCUS       DAMKOJ010000242          223 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.denovo.253, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000242 DAMKOJ010000000
VERSION     DAMKOJ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..223
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.denovo.253"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..146
                     /locus_tag="PC592_003664"
     CDS             <1..146
                     /locus_tag="PC592_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDF4057553.1"
                     /translation="EKGKMKDTMERAKLKSELDNLQRLVDRIPPDILAELKRQQRHTV
                     KER"
BASE COUNT           74 a           42 c           66 g           41 t
ORIGIN      
        1 gcgaaaaagg aaagatgaaa gatacgatgg aacgggcaaa gctgaaaagc gaactggaca
       61 atttacagcg gctggttgac cgtatcccgc cggatatact ggcggaactg aaacgtcagc
      121 agcggcacac ggtaaaggaa aggtgataga tataagcaga aattttcgcc gcctttgtgc
      181 ggcattgtac cttgaaaact gaatatggag gacactggat ggc
//
LOCUS       DAMKOJ010000243        61384 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.012, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000243 DAMKOJ010000000
VERSION     DAMKOJ010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61384
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.012"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            203..586
                     /locus_tag="PC592_003665"
     CDS             203..586
                     /locus_tag="PC592_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF4057554.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLENKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            588..938
                     /locus_tag="PC592_003666"
     CDS             588..938
                     /locus_tag="PC592_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057555.1"
                     /translation="MNNTITINISIIYLLLAILACIALVYLIIVLVKLHKILNTVGTM
                     LNENTQNINTTLNNLPSVVENFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(1038..1496)
                     /locus_tag="PC592_003667"
     CDS             complement(1038..1496)
                     /locus_tag="PC592_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057556.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSNGKADLLYSCRLQKILKEIYINQSRASYMSGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1544..2332)
                     /locus_tag="PC592_003668"
     CDS             complement(1544..2332)
                     /locus_tag="PC592_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF4057557.1"
                     /translation="MKVVIIPGHTLTGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNVTTSTPGGTETIYKTNNEKTY
                     AERVNTRLATVFKNRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGVNKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALKQIDKL"
     gene            complement(2471..2908)
                     /locus_tag="PC592_003669"
     CDS             complement(2471..2908)
                     /locus_tag="PC592_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HDF4057558.1"
                     /translation="MDKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQSGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3788..3874
                     /locus_tag="PC592_003670"
                     /pseudo
     CDS             3788..3874
                     /locus_tag="PC592_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606463.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3895..4044
                     /locus_tag="PC592_003671"
     CDS             3895..4044
                     /locus_tag="PC592_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057559.1"
                     /translation="MNVNDNLKSINRELCVKTYDNFKILHDKEINRLKELKLNGYKLI
                     SSMKI"
     gene            4321..4830
                     /locus_tag="PC592_003672"
     CDS             4321..4830
                     /locus_tag="PC592_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057560.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVELEVDNLKVISEKLEIINLQLVQRKNMRRKMFHWLF
                     ILLCSVIVIVFMVLGGLNSPYLNWNYTNPETAVFGVAFHAFECLFVRLTPIVLIGAII
                     GSFLTRKKI"
     gene            5221..5757
                     /locus_tag="PC592_003673"
     CDS             5221..5757
                     /locus_tag="PC592_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF4057561.1"
                     /translation="MQGGVDIRQVKSFVFPVISLIFLDQISKVLIGLFLMGFEIDITG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVIIGILHS
                     REISMKEYIYFCYRQFKR"
     gene            6515..7135
                     /locus_tag="PC592_003674"
     CDS             6515..7135
                     /locus_tag="PC592_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF4057562.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNAKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     KGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLKCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            7291..8073
                     /locus_tag="PC592_003675"
     CDS             7291..8073
                     /locus_tag="PC592_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF4057563.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVATHEYRSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            8198..9124
                     /locus_tag="PC592_003676"
     CDS             8198..9124
                     /locus_tag="PC592_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057564.1"
                     /translation="MSDILSRISNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSSIDPEEIHTLESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARAIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNDTVEMVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            9138..9644
                     /locus_tag="PC592_003677"
     CDS             9138..9644
                     /locus_tag="PC592_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF4057565.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPNPYTEQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAVLGYWLARNYWGKGITTN
                     AVKEICKIAFEKYNLNKIHANVYSYNRRSSKVLEKCGFKIEEYCHNSIIKNRNMIDCH
                     VYSLIRTQ"
     gene            9713..10374
                     /locus_tag="PC592_003678"
                     /pseudo
     CDS             9713..10374
                     /locus_tag="PC592_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            10665..11450
                     /locus_tag="PC592_003679"
     CDS             10665..11450
                     /locus_tag="PC592_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF4057566.1"
                     /translation="MAKIISVVNQKGGTGKSACAANLGVGLALMNKKVLVVDADPQSD
                     VSAGFGFRDCDNSNETLTTLMEMVLNDEDIPEDCFIQHTEEGIDIICSNIGLAGTEVQ
                     LVNAMSREFVLKQILNRVKDRYDTVLIDCMPSLGMITINALAASDEVLIPVEASYLPI
                     KGLQQLLKTIGKVRRQINPKLQIAGILFSMVDAHTNDARNNMELLHNAYGNQIHVFDN
                     YIPFSVRMKEAVREGQSIFKYEPKGKVAKAYMNFTEEVLEHGR"
     gene            11440..12369
                     /locus_tag="PC592_003680"
     CDS             11440..12369
                     /locus_tag="PC592_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF4057567.1"
                     /translation="MAGKKKSTPIPLQSLDALFGTTSEEQAGIQQIALDNLHSFSNHP
                     FKVLDDDKMIELSESVRTHGVLVPGIVRIKDTGGYEIIAGHRRKRACEIAGLKTMPVI
                     IKDLTDDESTVIMVDSNIQREELLISEKAFAYKMKYDALKRQGKRSDLTSCQVGKKLA
                     AEDISQNSEDSTRQILRYIHLTELLPVLLDMADHKQLPFNTAVELSYLKKEEQDILLQ
                     YMGNHEMVPSMKQAQEMKKCSKEHLLTYSEIDCICCQGKTEKLQVKLPEKKLRMFFPE
                     SYTKEQIEDVIFKLLEEWADNKERVQNDNHGCD"
     gene            12347..12658
                     /locus_tag="PC592_003681"
     CDS             12347..12658
                     /locus_tag="PC592_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF4057568.1"
                     /translation="MTIMDVIKKALLPLAAMAFWLWMVKTIMGVTGNTDLFMFLFLAG
                     LPFGIHKMCIILIPRGYDVGGTVGMIALSVIVGGLLGSLMIPYYIVRAIYVTIRYIVK
                     R"
     gene            12874..13272
                     /locus_tag="PC592_003682"
     CDS             12874..13272
                     /locus_tag="PC592_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057569.1"
                     /translation="MRERIKNKQITKEIRGQLPVIAPAMFRERGCSYCPYYAGSYEKF
                     PRCMMASCAWDDEEEHFHPVLRQMLPEFKRKMEKAEEKYLELKTAYELLMSMFEAEMA
                     QEELEKDECYDCCYAKCGPCIGLCYKTLKE"
     gene            13287..13685
                     /locus_tag="PC592_003683"
     CDS             13287..13685
                     /locus_tag="PC592_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF4057570.1"
                     /translation="MNTAIISGRLVRDPGYNETQNEKGLHKIAKFVLAVRRNYSDDVS
                     FIPVKAFAKKAEFVRDYLVQGTKVMVEGEIVTGSYDNKETGKKVYTTELFADRIEFAG
                     AKVQEKMPEPMEGDGFLNIPESMEEEMPFR"
     gene            13698..14090
                     /locus_tag="PC592_003684"
     CDS             13698..14090
                     /locus_tag="PC592_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057571.1"
                     /translation="MVMLNKEYMINHMRNENGSINIKNVVLAAACEATELFQCLIVMD
                     SNFTDWSRFVDRLEKNVERQDYEKVHELCQTMYAMRHLSEELEGLYLVRDDAELCSLY
                     YQIFVGMLDLTVFSTEAMVDLNGGKHDE"
     gene            14083..15006
                     /locus_tag="PC592_003685"
     CDS             14083..15006
                     /locus_tag="PC592_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF4057572.1"
                     /translation="MSNQDYMPVECLLVPKALFKDARYCSLSTTAKVLYSLMLDRLRY
                     AAQNKWIDQKGRPYVIYPKSEMIRDLNSTRYRMDYAVSELESMGNMVRVVKDNGRPNR
                     FYINDISKMNEEEKTMMTINDLMTMVGPEEAEEIMDKMVTAAREIVDDLMKKGYIEII
                     REGCPEGGPLEDGVPPIDLGEDEFNPEDLSPMEFRCYCDENGNLDDEAIEDDASEFGM
                     DLAFGVIELLENDPDRIEAIRQYFNHVYKMESMKRFMAVVETTAVICGNSPEWIEDMH
                     ACNKGARRIYLKELVSVFNMYLNMFKNKEME"
     gene            15020..15832
                     /locus_tag="PC592_003686"
     CDS             15020..15832
                     /locus_tag="PC592_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF4057573.1"
                     /translation="MDYEYFRVEESEQFSFFRIPKALFTEKEFEGLSTDAKLLYGILL
                     DRINLSKKNGWVDADGYVYIIYTVAELQEVLHMSHTTVTKLLRELDSVHGIGLIERYR
                     QGCNRPSVIYVKNFVKRIRAKPAVYYPSGTQEICCPERKNLEVRSAKKLQSGTQKIGS
                     PERKNFATNNTDINKTDKNDTDRSKSRSSEKESTCLYGRFGNVRLSVEENRELRKLYP
                     YDFQRMIDQLSAYMKSTGKTYQDHFATILLWAGREELKTGSGRYDFEEGESL"
     gene            15829..16626
                     /locus_tag="PC592_003687"
     CDS             15829..16626
                     /locus_tag="PC592_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4057574.1"
                     /translation="MTDSRNVADFLGEDGCLRCGVCGKRKQLRINFMGRDRVVGCLCD
                     CEAQARKEKEEQLRREEAQRELYQRKSVGLRDRRFWEWRFENDNGSNDKMLIARQYTK
                     NWEKMKKENVGLLLMGPVGTGKSFFAGCIANALLEQGERVMMTNFSRILNEMTNYQAD
                     KNQIVQNLVDYPLLIIDDLGIERNSEFALEQIYNVIDSRYCKMKPLIITTNLGLNDMK
                     DEALDVAHKRIYSRILEMCVPVYCGGADKRREEGTEKLGRMQSLISG"
     gene            16709..17200
                     /locus_tag="PC592_003688"
     CDS             16709..17200
                     /locus_tag="PC592_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDF4057575.1"
                     /translation="MQEEVTQKTVTFCVRTTKMTADVLKKVIAAYLRHQKQKSAEKKA
                     QKNQPKQGKITVKELAKQNAGMTNIEITPKNIKSFERYARKYGINYALKKDKTKDPPV
                     YMVFFKGRDQDAITAAFREFSQKEIQKANRPSIHKRLAAYRSIVAGKTKGKARNKHQE
                     VSR"
     gene            17221..19122
                     /locus_tag="PC592_003689"
     CDS             17221..19122
                     /locus_tag="PC592_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDF4057576.1"
                     /translation="MTNKLKAKARVTLSALDMKKLILTNLPYLFIFLLADRASCLYRA
                     SPGADMGNKLLYAMEHADRILTGFLPSLYYMDVLVGAGIAAVVKILVWQKQADAKKLR
                     KGVEYGSARWGTAEDIKPFMADDFWMNIPLTATESITMESRPKNPKFARNKNICVIGG
                     SGSGKTRFFVKVSIMMMNCSMVITDPKGTLIEECGKMLAKGPPKRDKHGNVVKDKSGK
                     VVHEPYVIKVLNTINFSKSLHYNPFAYLKSEKDILKLVTVIIANTKGEGEKATEDFWV
                     KAEKLLYTALIALIWYEGDEDEKNMNTLIDLLNESETREDDENYKNPVDMLFEDLEKR
                     NPEHFAVRQYKKYKLAAGKTAKSILISCGARLAPFDIAELREIMSYDEMELDKVGDRK
                     TALFLIMSDTDTTFNFVIAMLQSQLFNLLCDKADDQYGGRLPVHVRVICDEFANIGQI
                     PQFDKLIATIRSREISASIILQSQSQLKAMYKDSADTILGNCDTMLFLGGKEKTTLKE
                     MSELLGKETIDLYNTSETRSNQKSFGLNYQKTGKQLMTEDEIAVMDGGKCILQIRGVR
                     PFYSDKYDITKHPNYRLLADYSEKNRFKVEKELDPKYSPKPDDEVEVMEMDLSEDGNE
                     QENNEERNN"
     gene            19197..19412
                     /locus_tag="PC592_003690"
     CDS             19197..19412
                     /locus_tag="PC592_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HDF4057577.1"
                     /translation="MAFFTSAITTLKTLVVAIGAGLGVWGVINLLEGYGNDNPGAKSQ
                     GIKQLMAGAGIMLLGTTLIPQLATLFG"
     gene            19424..20293
                     /locus_tag="PC592_003691"
     CDS             19424..20293
                     /locus_tag="PC592_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057578.1"
                     /translation="MNTIIERITEAIKEILIGMIQNGLEGMFVEVNDKVGTIASQVGQ
                     TPQGWNTGVFNLIQNLSQTVIVPIAGLIITFVLCYELITMVTQKNNFHEFETYNIFLW
                     IFKAYVAIYLVTNTFNITMAVFDVGQHIVNGAAGVISGSTAVDASAAIATLTESLEEM
                     EIGELFLLAMETLLISLTMSILSVIITVIMYGRMIEIYLYTSVAPIPFATMTNKEWGN
                     IGNNYLKGLFALAFQGFFMLVCVGIYSVLVNAMTISTNLHGAMFSVAAYTVVLAFSLF
                     KTGSLSKSIFNAH"
     gene            20322..20783
                     /locus_tag="PC592_003692"
     CDS             20322..20783
                     /locus_tag="PC592_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF4057579.1"
                     /translation="MAYVPVPKDLTKVKTKVALNLTKRQLIFFSLAAVVGVPLYLLAK
                     KPLGSSVSAILMVTVMLPFFFMAMYEKDGLPFEKVMGNIIRQKFICPAKRPYKTENFY
                     QAVDSLVKKEGVPDGKKEETGTAAVPGSGGKKKPSGKKKKKRQKGKGKGKA"
     gene            20668..22905
                     /locus_tag="PC592_003693"
     CDS             20668..22905
                     /locus_tag="PC592_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4057580.1"
                     /translation="MAKKKKQAQQQCLEAAARKNRQERRKRNDKKEREKEKLRKKQEK
                     ERKRQKNIPHTAQQSIPYQRMFADGICQVSKNFFSKTVQFYDINYQLALNEDKTTIFE
                     NYCDFLNYFDSSISVQLSFINQQVDVAEFEKSIDIPDQNDDFNEIREEYRTMLKNQLS
                     KGNNGLVKSKYITFGIEAESLKVARPRLERIEADILNNFKVLGAQAHPLNGVERLEIM
                     YHVFNQDRIEPFRFNYKMLPQTGLKTKDFIAPTSFNFSKNSSFMMGKTLGSVSYLQIL
                     APELTDRMLADFLDVDESINVNIHIQSIDQTSAIKMIKSKISDLDKMKIEEQKRAVRS
                     GYDMDVLPSDLVTYGEEAKNLLEDLQSRNERMFLVTVLVMNTAKKRQKLDNNIFQVQG
                     IAQKYNCSLRPLDYQQEAGLMSCIPLGVNRIEIQRGLTTSATAIFVPFTTQELFQEGE
                     ALYYGLNALSNNMIMVDRKRLKNPNGLILGTPGSGKSFSAKREITNCFLITEDDIIIC
                     DPEAEYYPLVQALHGQVVRISPVSTQYINPMDLNLNYSEEDNPLSLKSDFILSLCELI
                     VGGKNGLEPVEKTIIDRCVRLVYQEYLSDPVPEKMPILQDLYDLLRGQDEPEAQRLAT
                     ALEIYVTGSLNVFNHRTNVDINSRIICFDIKELGKQLKKIGMLIVQDQVWNRVTVNRS
                     AHKSTRYYVDEFHLLLKEEQTAAYSVEIWKRFRKWGGIPTGITQNIKDLLASREIENI
                     FGATR"
     gene            23638..25521
                     /gene="ltrA"
                     /locus_tag="PC592_003694"
     CDS             23638..25521
                     /gene="ltrA"
                     /locus_tag="PC592_003694"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF4057581.1"
                     /translation="MTMKKKKQLLCEDNLRHNEYYGMQNTIDNLYQASLNGEVFTDLM
                     SVILQRENILLAYRNIKKNTGSKTNGTDNLTIEDIGRCSPDEVVEKVRFIINGSEHGY
                     RPKPVRRKEIPKPYDPSKTRPLGIPCIWDRLVQQCIKQVMEPVCEAKFSKNSYGFRPN
                     HSVENAIARSYQLLQHANLHYVIEFDIKGFFDNVNHAKLIRQIWAMGIHDKKLIFVIR
                     RILKAPIKLEDGTFITPDKGTPQGGIISPLLANIVLNELDHWVESQWQWCPICKRNTR
                     PDNGYRQAKKSNLKEMFIVRYADDFRIFCRTKDSAERTKCAVTLWLKERLKLEISEKK
                     TRIVNVRNHYSDFLGFKMKVHRKGNKLVVISHIADKNLEHKREKLKEQAKRIAHPRKI
                     YGEQGEIRLYNSMVTGMQNYYCIATHVNHDCASLNRTVMTLLTNRLSTRTGNRLVKTG
                     RELTEFEKARFGKSKMMRYVAGTNEPVYPIGYTQHKNPLFRKKSWNYYTPEGREGIHN
                     CLRINIPMMLALMRQPVYSNSAEYADNRISLFSAQWGKCAITGVEFSSVGEIHCHHKL
                     PRHLGGTDAYENLILIKNSVHKLIHASKAETIYKYMDLLQLDNKQLIKVNHLRELASM
                     QPI"
     gene            25683..25910
                     /locus_tag="PC592_003695"
                     /pseudo
     CDS             25683..25910
                     /locus_tag="PC592_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
     gene            26024..28804
                     /locus_tag="PC592_003696"
     CDS             26024..28804
                     /locus_tag="PC592_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDF4057582.1"
                     /translation="MAEQRMKAREKTVQKMTKDGLVEENLADKSTVRVSSRTRDVQMS
                     KKDTGKGMDLSNRRGTREDSTDPVRHSVQNSRDAPAKAQTVDKAKSRKMIREQAEGSS
                     KLSLEEKKNGSGKLQEKHTDLAQSRGDARKKQNGGSKKPGQKQRLKFAYEETAEAVRD
                     GNSSAKLNRMDADGVNFRHDAQKKRNQKMAHTEAERKNAPKKHSMKEKVYQENAESAG
                     AKKKSRLKFEGESPKDTSLVKKAGTAAAVSVHRQVRKNDDGNAAVEGANSLAEGSEGL
                     YHLEQRSARRRNRRKSRSSAYQAKKTAQAAAESSINQERSYLKKLIQKQRIKKEYSKA
                     KQSEQAMGTAAVGTIDYIKKIGGKVTNFFKEHRKVYISIAALIGMMFLIMTSVTSCSS
                     AFMQSLINYTGTSYISSDEAIRQADLYYTQLETNLQERINQMESEEPGHDEYRYNIGP
                     IEHDPFVLISYLSAKYEEFTFEQVKPELDRLFALQYQLETEVVNETVTETTTVRVGES
                     LGNVVTSGYCNCPICCGIWSGGPTASGVYPTANHTLAVDASNPFVPMGTKVVMNGVEY
                     TVEDTGAFARYGVQFDVYYDSHSAASAHGHQTWECFLADDNGSREVEVTRTRDVDVLN
                     VTLNSGSLTGICQSRLGIFQRELFAAYNETKGNLQMFGTPFDFNWYYNVSSYYGYRIH
                     PISGANQLHNGVDIGVPEGTEVLAGLTGTVTTSAYNDSYGNYVVIKDSKGYELRYAHL
                     KSRSVFAGAAITKGDVIGLAGNTGNSTGSHLHMELLKNGERMNPIFYLETGEGTIFGG
                     NEYTSEAAQRLLQEAARYLGTPYVWGGYSPSGFDCSGFVSYCLTNSGVRNTGRLTAQG
                     LYDICTPVSESDVQPGDLIFFTGTYNAGVPVTHIGIYVGGGQMIHCGHPVQYTSIYSS
                     YWQSHFYGFGRW"
     gene            28842..29162
                     /locus_tag="PC592_003697"
     CDS             28842..29162
                     /locus_tag="PC592_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HDF4057583.1"
                     /translation="MKSLEKAVADYEKAKEKMEASRARYEADLKRFKAAEAAKTEAEN
                     LEIVRIIRGMDMTIPELNAFRERMKTELPTLAGFQKEETRADDEFRENERTEGTGQAQ
                     EMGQ"
     gene            29101..30480
                     /locus_tag="PC592_003698"
     CDS             29101..30480
                     /locus_tag="PC592_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF4057584.1"
                     /translation="MNLEKMKEQRAPGRHRKWGSNVKRGVFAVTTFLCMATPFFSARS
                     IYAAESTNPAIAIEKPDGWKQGDTSVSITVDASQMGEGFKVAKIEAKTGKDGSWQDVT
                     ESRSITINGNQTIYVRVTDAEGTVYEQNRSIRCYDTEKPTLSASLTDGVLTIQGNDAV
                     SGISAVTVNGTTYTELSDGKLKVQLTQKDFTTKQIEITVTDGAGNTSDKYTLQNPYYE
                     WAVRQAQQQSTANSDMSTTGSAATTEETATSPLPQDAQASEPTEARGTVDDRTVTGIE
                     EELAASGEDAENITQTATEGTKEFYTISTKSGKVFYLVIDNSRSQDNVYFLTEVSEKD
                     LMNFTLSDTVTLPEVDTVYAEPETEEPEPTQEPEEEEQETEEVQMPEDKSPVGSYLLI
                     GLAAAGALGAGYYFKVYKPKHEYDDEDEYEDDESEEAEEPAEPDDAEEETLPDEEDPE
                     EVLEDEEES"
     gene            30499..31059
                     /locus_tag="PC592_003699"
     CDS             30499..31059
                     /locus_tag="PC592_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007593032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine methyltransferase"
                     /protein_id="HDF4057585.1"
                     /translation="MKKYPVIYADPPWQYRVYSKKGLGRSAESHYPTMGIDEIRALPV
                     AELAEKDCALFLWVTIPCLLEGLSVLQAWGFQYKTIAFVWIKQNKKADSLFWGMGYWT
                     RSNAEFCILATRGSPKRQSAGVHQVIVSHIEEHSKKPQEARERIVQLMGDVPRIELFA
                     RQKTPGWDVWGNEVESDIDMESRKDE"
     gene            31061..33133
                     /locus_tag="PC592_003700"
     CDS             31061..33133
                     /locus_tag="PC592_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005344197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF4057586.1"
                     /translation="MKLVIAEKPSVAMALAKVVGARERKDGYVEGKEYLVSWCVGHLV
                     AFCDASEYDERYKKWRYEDLPIIPEEWKRKVLDGTKKQFQILKKLMNSKEVDEVICAT
                     DAGREGELIFRFVYEQAGCKKPVKRLWISSMEERAIKEGFASLKDGSCYEDLYQSALC
                     RAKADWLVGINASRLFSVLYNQNLKVGRVQTPTLAMIVDRNQKVKEFVKEKYYVAHLT
                     FGEFDAVSEHFQKKEEADQVAADCSERMCQVEKEDVQTKTVRAPKLYDLTSLQRDANR
                     IFGYTAQQTLDSVQEMYEKKLVTYPRTDSQYLTDEMGNSTKQLIQLLLSRMPFAEGIA
                     YEPDISKVLNSKKVSDHHAIIPTSEVEKADLQKLKEKERNILYLISARVLTATADPYI
                     YETHKCQLTCNFHTFYFNARKTKQEGFQAIEKKLKQFLGVREPEQEAEFDLYLGRNIG
                     PCSTSVSENFTQPPRQYTEDTLLAAMERAGNEELTEDTEKKGLGTPATRAGIIEKLIQ
                     SGFVKREKKNLVPTDAGNVLVTVLPDEIKSPKMTAEWEMALNHIAQGTETAEHFLNGI
                     TDMLGELISRYHSISEEESSRFPGTAMGEVIGKCPVCGSDVREGKKNYYCTGQECRFS
                     LWKDDHFLASQGKKMDKATAKKFLKKGKVHYKDLVSKRTGKSYEATVEMVADSEGKAQ
                     FNLHFPQR"
     gene            33199..39567
                     /locus_tag="PC592_003701"
     CDS             33199..39567
                     /locus_tag="PC592_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDF4057587.1"
                     /translation="MRRTGHLRRLVSGFLAGLTMLSTVLSPMTAYAAEPKAEEKPPLY
                     EEVKDLLDEDEVVKAKDFEITVGSEFDVTCDFTGLEIKDDKKVKVTFEEAKNEEGKDF
                     ALDHADSYKAVYYVEPVNEAHPKYQISRNLIVKEAETEVQAASEGGGEDAGSGGTEEA
                     ADDGEADSQTFSAEESETTETSMETEAATEPVTEAEPETETVESTEVLPEEELDAALE
                     ESEGQETVDSETGLSVSDVLEQGEEQGIDMLSLEEGETVQFQAQALFASARSTTSVSV
                     TRGAYYYYADYGLGSYLTAPYTVKFGDVTATAYCVQPSKPGPGDGTYTITKLSDGKTL
                     AKVCYYGTKASGDEGFFAEKHPDFSTGKRFIITHLAAAYANGSSDAFSGTNSTGQALA
                     MELYNYCVSQPEIPDVAMSFSNAKVKAYIDGNSQRTEEITFKADALQTITMKLPSGVK
                     FHNVSTGKTSAAGASVEVSGGTKFYLSAPLTQAEDVSGSWAVTMKGSITKDYSAYKIT
                     TGSSTQDLALVFGEGVTDEKYVDFSVEWVKMAKIEIVKKDAGSNAKVAGAVYGIYSDE
                     AGKNLIAKMPATDANGASSITIEKTQNTVYLKEISVPNGYVLDTKAYGINLVIGGTTK
                     KDVTDKEQFADLTVYKEGEVLTGASVTDSGVVFQYTKQRLKGAVYNVYAGADIKAADG
                     RVIFQKGALVKEGLTTGEDGSATLKNLHLGTYVVTETKAPADYVCKGESKTVTLSYAG
                     QNVEVAVGNVTFANDRQKASVSVVKQDDTTKNPLSGGIYGLYAAENIADVSGNVVVGK
                     DTLIEKATTGTDGNAVYQADLPINHSYYVKELQAPANYFRNSEDVFSFRFQYTNDKQA
                     SVAFTHTFENERVNATIHLVKKDKETGRNTQGDAAFEGAVYGVYARENIIHPDGKTGI
                     LYKAGSQVATMTVDKKGDASVVDLYLGKYYVKEITPPIGYLIDEGEYDLECSYEGDLV
                     KTVERSTESSEQVMKQPFQVIKAANNGKTDADLLKGAGFTAYLKSSLKTNPDGSYDFA
                     SAKPVVLTADGKTEMFTDAKGYACSIPLPYGTYLVKETTTPHNYKPVDDFLVTISENH
                     PDEPQIWRILLDDEFKAKLKIVKKDDETKRPVLVAGTEFKIYDLDHKKYVEQVTTYPT
                     TVTHKSYFTDSQGYLILPNNLSIGHYRIEEVTAPDGYTLNQNYVEIAVDSNTAYQMDS
                     VSGDVVIEVDYENHPVKGKLTVYKKGEMLAGFNKDFIYEEQFLKDAVFEVYAAEDIYS
                     TDYQKDADGKRIVVYAKNTLVTTITTGDDGMAVAENLPLGAYRVVEKTAPDGFVLNPE
                     AAEVVFVYEGQDTPVVEQEVTVGDERQKVAITVEKQDAENGAVVAGAVFGIYNKEDIT
                     ADGKVIVEADTLLQEMTSDEKGQAGCTLDLPLGSYYVKELKAPAGYVSSNEVLNFDAS
                     YQGQDVETVVLKAVKKNQPTTVEITKSDITTGTELDGASLKVLDKDGNVVDEWTSVKD
                     APHVIKRLVVGETYTLREEFAPYGYLKATDITFTVEDNGDVQKVEMKDEVPTGLLIIN
                     KKGEFLDKVTLLDNAKGTVEHLFEYITGSLTEVTFHVYAAEDIKAADGVSEDYFKADE
                     LVGTITTDTNGIAQLGDLPVGKYYVKEAETAHGYVLDGEPRYVDLSYRDQDTPVVTYD
                     EAWQNNRQKVKVTVLKKEKDTERVLAGGIFGLFTREDIKNASGDVLLEADTLIELKTT
                     DENGQITFTADLPVDGNYYVKELYAPDGFVTTNEEQDFIFEYAGADQAEVSYDFTFEN
                     EATTVELTKSVLTTGDELPGAHLKVTDEDGNVVDEWVSTEEAHVIKELVVGKTYTMTE
                     TKPADGYVTAESIEFTIENTAEIQKHEMKDDVTKVQISKTDITGDQEIPGAKLTILDE
                     NDQVVESWTSTEEPHYVEKLPIGRYTLREEQAPKGFILTADVSFEVKDTGEIQTVVMK
                     DDTAKGKVILNKTDKETGEPLKGVEFELRDSKGKVLETLKTDAAGHAESSLYEIAEYK
                     DGKFAGEKKYYLVETKTLDGYTLDETEHEVVFAYKDDSTPIVEVTFDLTNDKPEVPQT
                     TEGTPGTPSADNPKTGDETNLWIPVVLLAVSVSGIAGLLADRRKRKRK"
     gene            39646..39786
                     /locus_tag="PC592_003702"
     CDS             39646..39786
                     /locus_tag="PC592_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057588.1"
                     /translation="MKKTMNTVQAGREMQERSFKRMMAYQKKAEQAVNKKRMNQHMIR
                     RG"
     gene            39793..40881
                     /locus_tag="PC592_003703"
     CDS             39793..40881
                     /locus_tag="PC592_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057589.1"
                     /translation="MMNRKDFFEYVKDNVKDYLPEKYADANIHLQEVVKKNGLTLTAV
                     VIPAKDTNITPNVYLDSFYQEYRNGKSPDACVGDVADLWIEKMDTDLDVDVNGMMDYG
                     NVKDKLQVRMCDPEKNREWLEDKAVTMHGDFAAYYTVNLSENKDGIASVSVTKALLEA
                     WKIDVQTLHQDAMASDKNRGPALYAINDLMESSIMGEKPQNLLNGERRAEEFFMPMFC
                     LTNETKMNAASLILHEDIRKQIGEFMKGDFYILPSSIHETLLLPDNGDFDVKALNAMV
                     KEVNATEVALEDILSDKVQFCDGRTAVMENAEKREARLEKEKAAAAEKPAEKTGIHGK
                     LEKAKEEMKAGDVLVKPQGKTRDTAMVM"
     gene            40942..41259
                     /locus_tag="PC592_003704"
     CDS             40942..41259
                     /locus_tag="PC592_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HrcA family transcriptional regulator"
                     /protein_id="HDF4057590.1"
                     /translation="MYMSEWCLYGDDIREKFERRLEPDSLEGELIRYKEVLGEEFGLK
                     ELLTIQDLRVKVLIAQAINNVPEFLLDQIGKARNSYEFPSLVRELERIADVMEEVVEG
                     EGE"
     gene            41256..41402
                     /locus_tag="PC592_003705"
     CDS             41256..41402
                     /locus_tag="PC592_003705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057591.1"
                     /translation="MSSKMKKEERKRLSGYLRKCLESQKDQEFILQIPLKRGASESEK
                     KIRN"
     gene            41380..42021
                     /locus_tag="PC592_003706"
     CDS             41380..42021
                     /locus_tag="PC592_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HDF4057592.1"
                     /translation="MRRKYGIDQVSVRLVKEAPILSEKEISTPEDAIRVLGDTFKDYD
                     REVVGVVHLRSDNVPINMTIISMGTLNQSLVHPREVLKAAFLSNAASILLFHNHPSGS
                     LKPSKEDIALTGRMQQLCMLAGIPVIDHVILGNDQSYFSFREKQILPMEQIQYSVDLN
                     DINLKVAEKEAENYGYEKPHKKSIKESLEENRKKITSGQKTSGVKKKRETTIE"
     gene            42039..49718
                     /locus_tag="PC592_003707"
     CDS             42039..49718
                     /locus_tag="PC592_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012744286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF4057593.1"
                     /translation="MANKLYAMEQLTEEVAKDIAAKPEEWMRFLDTASRLYKYTFDEQ
                     LLIFAQRPEATAVASMEVWNKRMYRWIRKGSKGIALIDYTSSPKNRLRYVFDISDTYK
                     VRNLGKDPALWVLPQDDRFLAADYLQRAYGLDEGDGGLAGTLHQAAQESVREWLPDAF
                     DELKQDVQGTFLEELDEQNQEVEFRDLMTDSVWYVLLKRCGMDTEEYLSVDSLRHITD
                     FNDLRVLGHLGTAVNEICRPILMQLGRYVLMDLENDRKTVAKESEVVYNEFNTLIRES
                     GEITPEPEIEENKEVTEHERDHLQQERGLSDPGYQTGGDQGNHREIRDDAEGISEEPQ
                     ESQIQHTGTAEQAGQPSDESGQRSQTESGRPDHAASGESPGTGEISRQHGMDPSHEPD
                     PRTGRGDGGSGDYIQLSLFPTEEEQFGEIRKAAAALTQPAAFFVSDEIVDDVLRTGSG
                     RKNTLFHITAKLVEGIDHEKLRSFLIQEYGTGGKGFEFSGQKFSVWYDGDGMRFRRGE
                     SARHNYDRMLTWEEAANRIQDMYDAGTYVSNVIMQNSIKVECDELSSQLALHFRDTGA
                     IRGIYSHTETTERFRAGLDDPKQTREYYQMLEELERDMERHPENYMRYQIRNNPIYKQ
                     RVYDLGRTLDWSRQEEIIIPPEMAFITQDEIDSVLRRGGNVAGGRSRIYEFFMEHHDE
                     KEAADFLKHEYGDGGCTPGIQGSDLSDEWHDAKGIRLSKGQISNPSLTTLVKWKQAAS
                     RTRQLIRMDDFLSPEELEKYEERQEAQRLADMEEVKQSLGTEEVSEEVEEVHAEENVE
                     DKPEESGQPLRAEDVQNLVLVNRQYSSVSRTTEYDFTCEIRGEQDILHYMVEYHDDGE
                     GFTIHTEKDDIWERMSEPELERLERVLEREALYFQYHEDIENAANLEELREVQYSIME
                     NESIYFRQISERVWSEYGQRERELSVEIPPVNFHITDDQLGYGTAKEKFRANVMAIRV
                     LKKCESENRYASPEEQEILSNYVGWGGLPDAFDESKASWSEEYQELKDLLTKEEYAAA
                     RESTLNAHYTQPVIIESMYQLLQNLGFEKGNILEPSMGVGNFFGMLPDKLQQSRLYGV
                     ELDSISGRIAKLLYPNADIQIKGFEKTDYPNDFFDVAIGNVPFGSYKVNDRQYDKYHF
                     MVHDYFLAKTIDQLRPGGVAALITTKGTMDKASPEVRKYLAERAELLGAIRLPNNAFK
                     ANAGTEVSADILFFQKRESISMEEPEWVTLGEDVNGISINRYFITHPEMVLGTMAEVS
                     GPYGMETACLPLEGADLAEQLEDAVAKIHGTMVPAVTAETELDEIMESIPADPSVRNY
                     SFTVVDDQIYYRVNSLMNPVKLPATTAERVKGMVEIREVVRELIALQMEENATNEAIQ
                     ELQVKLNQVYDAYTEKYGVIGSNANKRAFSDDSSYCLLCSLEELNEDGTLKRKADMFT
                     KRTIKKAVAVTSVETAAEALTISLNEKARVDLPYMAGLTGKTEEKVAEELTGVIFRDP
                     VNGQWETADEYLSGNVREKLKMARIFAENHPEFTSNVNALKQVQPVDLDASEIEVRIG
                     ATWIAPEIYRDFMVELFDTPGYLVGRVIDIRYSEASGAWNISGKNADSDRNVLTTATY
                     GTSRINAYKILEETLNLKDVRIYDTKLDAEGNEIRVLNKKETMLATQKQDAIKEAFKD
                     WIFRDQEQREKLCRIYNERFNSIRPREYDGSHLTFPGMNPEIELRPHQKNAVAHQLYG
                     DNVLLAHVVGSGKTYEMVAAAMESKRLGIAQKSLFVVPNHLTEQWGAEFLQLYPGANI
                     LVATKKDFEPSNRKKFCARIAMGSYDAVIIGHSQFERIPLSEERQKKIIEEQIEELEE
                     GIQQAKLESDGSRFTVKQLEKTKKSLRRRLEKLENKEKKDDVVTFEELGVDRLYVDEA
                     HYYKNAFLYTKMRNVAGIAQNEAQKSADMFNKCQYLDEITGRKGITFATGTPVSNSMT
                     ELYTMQRYLQYGKLNRMGLGHFDSWASTFGEVVTSIELAPEGTGYRAKSRFARFYNIP
                     ELMSMFKEIADIKTADQLELPVPEAEYETVVLKPSEHQKEIVESLGERAEVIRDGGVD
                     SSVDNMLKVTNDGRKLALDQRLVNPLLPDDGDSKICACVEKSFAIWKETASKRSAQLI
                     FCDLSTPKGDGTFNVYDDLKKKLMAKGVPEAEIAFIHDANTEVKKTDLFSKVKSGQVR
                     FLLGSTAKMGAGTNVQDRLIALHHLDVGWKPSDLEQREGRIIRQGNRNKKVHIYRYVT
                     EGTFDSYMWQLIESKQKFISQIMTSKSPVRSCEDVDDTALSYAEVKALATGNPAIKEK
                     MALDVEVSKLKLLKANFVSNHYRLEDDIAKNFPQQIAVLRESIEGFKADMEQYQANKT
                     TDPEKFVMEVGGTVFYEKKEAGAALLAVCQSMKQADAMINVGQYQGFSIRLKFDSWNK
                     EFILSLKNENVYRVSLGSDENGNIIRINNALEAIPQKLAEAERKLETVQGQLKNAMEE
                     VKKPFPKEEELNQKLERLSELNALLNMDEKETVVEGEEEQGEEKEEHQSLHNRITAIK
                     QNSQRQDGKEPAMRTSEVCIG"
     gene            complement(50110..51261)
                     /locus_tag="PC592_003708"
     CDS             complement(50110..51261)
                     /locus_tag="PC592_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005343049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HDF4057594.1"
                     /translation="MKHPTVQDIFLRFYPEYLDKYKPSSQQFKVANCIINCKTGAYGA
                     NVSMCEDCGHLQIHYNSCRNRCCPMCQALPKEMWIDKRREDVLDAPYFHVVFTVPQEL
                     NSLIYSNQQLLYDAMYHSVSATINELTEDTKYLGAKIGYICVLHTWGSEMNYHPHIHV
                     ILLGGGLTSNNQWRDKGEEFFLPVKVLSKLFRGKYLDELKNLWEERKLQFHGSSEKYR
                     NHYAFKELLNTCYEKDWVPHCKKTFNGAQSVINYLGKYTHRIAISNHRIIRMDEDTVT
                     YYVKDYREEGKWKEFTISGVEFIRRFLMHVPPKRFVRIRHYGLLCTRTKTRHLTLCRN
                     LLGCKQYLSRLKDLDTPQILETLYGIKVTVCKRCGGHLRKPQQRIPLRI"
     gene            complement(51261..52103)
                     /locus_tag="PC592_003709"
     CDS             complement(51261..52103)
                     /locus_tag="PC592_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013976755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4057595.1"
                     /translation="MYEDIFELVTIAAQKKNLKESTTKAYCHALSPFLNATGKPWQEL
                     TVADADDYLTTKRRMGILPETYNHYYGALRFMYKRVLKLNWDEDEIPRMKRDRSLPTV
                     LSREEVNAILDVTTNLKYKAIFAVMYSGGLRVSEATHLHYDDISRSNHSIHIRNTKNR
                     MDRYTILADRTLDILTQYWFQCQRPRNILFPSQTTGEYLDISAVNQVLRRSSERAGIP
                     KHVTSHAFRHSFASHLLEDGCDIKYIQALLGHLDPKSTEIYLHVSNKTLLGIKSPFDI
                     QEDS"
     gene            52246..52392
                     /locus_tag="PC592_003710"
     CDS             52246..52392
                     /locus_tag="PC592_003710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057596.1"
                     /translation="MKFVIGGALTILFWDDPVTAFFGKSKKLRHSLGRPSRSDFVHFE
                     FYGQ"
     gene            52843..54303
                     /locus_tag="PC592_003711"
     CDS             52843..54303
                     /locus_tag="PC592_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011133547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HDF4057597.1"
                     /translation="MSMIKIENLTFSYPTSYDNVFENVSFQVDTDWKLGFVGRNGRGK
                     TTFLNLLLGKYEYSGKILSSVQFDYFPYPVSDKNRITEDILQEVCPLAEEWELMRELS
                     YLDVDVDVLWRPFETLSNGEQTKVLLAALFLNEGHFLLIDEPTNHLDAKARKSVATYL
                     KKKKGFILVSHDRRFLDDCVDHILSINRANIEVQRGNFSSWMSNFEQQQEFELAQNER
                     LQKDIRRLQQSAKRSAVWSERVEASKIGAADKGYVGHKAAKMMKRSKSIEARQQQTIE
                     QKSALLKNVETAEALKIQPLNYHTDLIASLSNVVVCYDGISVCEPVSFEIRQGERIVL
                     DGKNGSGKSSLLKLVVGQSIDYTGTVTLGSGLVISYVPQDTSYLCGTLSEFAEENNLD
                     ESLFKAILRKMDFERIQFEKDIKDFSGGQKKKVLIAKSLCEKAHLYVWDEPLNFIDVY
                     SRMQIEQLITEFAPTMLLVEHDNVFRDTVASNIVNI"
     gene            54485..55249
                     /gene="srtB"
                     /locus_tag="PC592_003712"
     CDS             54485..55249
                     /gene="srtB"
                     /locus_tag="PC592_003712"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HDF4057598.1"
                     /translation="MKRTEKVLLIVFLVVTLICGKYLLDYWQDSYDNRQNYRQVEEIA
                     FPEKDTEEDGTGSNADNPMTEIDDFDYQALLDENADCIGWLKIDGTDISYPVVQGEDN
                     EFYLRHDFQKNYAICGTLMLDCRNDIDAGQEHLIIYGHQMKDGSMFKQLNGYKKEEFY
                     HEHKEITLYLENQKYQYEVAAVYVTNVAQSGGYYDFLHKETRKQQMDYLQKMAAYQLY
                     PLGVTVREDDELLSLSTCEYSSTNGRLIVLARRIGA"
     gene            55263..58364
                     /locus_tag="PC592_003713"
     CDS             55263..58364
                     /locus_tag="PC592_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HDF4057599.1"
                     /translation="MAMNRNMTMAEKEVRDYAQKQMERAEQWENILFTEEQKEQVLEY
                     AAMTGDDYDIRKMIRDLADAVRSSDEEKVDEILRDAREEIDEFPDRSVGMAELKGYGY
                     TADDMFPLRQEMALELHRVGEKVYCLQSEGTHGDYASREMILEHEGLYGIEKEAWQRM
                     QEQEDEIDFEEAGLYQPPMIDLDRNEALRMFDAGETVYLITTYPRPIAVRKRMEIERG
                     PERYQMEREDVERIRTLEKRMQEYPQITSLKEAKLLLGTENRYGIYQIIDGSPGRKYE
                     FMDLNFIERHGYQVKKEDYELIYSDEMHYGDTLDSLYEKFNIAHPEDYTGHSLSVSDI
                     VVLNENGNVKAYFVDSISFRELPDFLQLEPELNQEEVAYRIGDQYFAIQVATEGYDYS
                     FYDKEYKLMDGGILENPDISMRQAIQDILEDEGLEQLERIPVDYDELQEKAEEVEAEI
                     LQEVRSQRKRVPVISDYIKAEAGLNGMSRSEIEETIWAIAQAEIIENDLDARIQAVRV
                     YGSRTRDGLYKQDSDVDVVIAYEGTVREDDLFSALNEAGYKVGNMRVDMNPIRPDKTG
                     TLEDFLEKSERYLDEKTEQMKARGEYKPLAKVEELEEANYNMIDNVLNNMPPKKEPYL
                     EYYAAECDEYHSLGKIYKSTNLDEIFAKYREIIDDPTLSYYGNGMGIIYRDPNDTFYD
                     EAEVSLVSRKSIRGDSLDDVAFLAALPMVHEALEKIVEAFPDFRYYPPKELDVHYYPE
                     KMNADELAAALDQLAEDFDHYDYHDNFSPEEDMVETVALELRCGYAHRYIPFLKDIID
                     EECEESPRAEELLEKLKAYQPEIPETAVPVVRINFCEDKEMDISGYQKLGSLDEITAK
                     MDAELASQADSKTGMPEKTVQMYFTIYYPDHDQMQELKGKINIGDGNGGIVSQLKNQN
                     EMKMHDESWLNYQKGKGEESFQAYIADLTDMQEHVLPYLQSFCSLEERAPERSVESTT
                     VSKSEMEAGKTITSGKNEKAKPVEPVKKSIHERLKINKEIIAKQQGKDEPERGVGKDL
                     RTV"
     gene            58505..59332
                     /locus_tag="PC592_003714"
     CDS             58505..59332
                     /locus_tag="PC592_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF4057600.1"
                     /translation="MPKGSNQKFKLYRLAEIMLEKTDDEHYITMSEIKESLEEYGITA
                     DRKSLYADLKDLEILGIEVEGEPVKNKYHYHVINRPFELPELKLLVDAIQSSKFITEK
                     KSNTLIRKLEKLVSKYDAQKLQRQVYVSGRIKTMNESIYYSVDAIHNAITENKKIKFQ
                     YFQWNVKKEMELRHGGAYYYISPWGLSWDDENYYLIGYDSEASMIKHFRVDKMLHIAL
                     LDENREGKEHLKKMDMADYAKKSFGMFGGKEQTVKLLVDNTLSGVIIDRFGKNVIFY"
     gene            59505..59867
                     /locus_tag="PC592_003715"
     CDS             59505..59867
                     /locus_tag="PC592_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005422970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057601.1"
                     /translation="MKNVLLDKGIILPSGEISKDKVNLVTGAITQPFAEMVWVTTGGD
                     METVNRLTDVLVTMNTPADRGKLFKIIKMLYGLMGLPFSEEAEPMDADPAVLEYFIFS
                     FTADFGEVIQDLIAEEAE"
     gene            60078..60998
                     /locus_tag="PC592_003716"
     CDS             60078..60998
                     /locus_tag="PC592_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4057602.1"
                     /translation="MAVFRVERNKGYTVMSNHHLRNKELSLKAKGLLSQMLSLPEDWD
                     YTLAGLSFINREKIDAIREAVKELERAGYIVRSRERDEKGRLRGADYVIFEQPQTPPV
                     SDLPTLENPTLDNPTLEKPTQKKPTLENPTQLNKDIQKTNLPKKEKSNIDLSSTDSIP
                     IHSLNPLPYDGEAAEPPERKRKEATDAYSVYEEIIKDNIEYDHFVRYGQVDKDRLDEI
                     VSIILETVCSKRKTIRIAGDDYPAELVKAKFMKLNSSHIEFVFDCMKENTTKIRNIKQ
                     YLKAVLFNAPNTIDSYYTALVAHDMATGKI"
     gene            61013..61237
                     /locus_tag="PC592_003717"
     CDS             61013..61237
                     /locus_tag="PC592_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDF4057603.1"
                     /translation="MAQKTGALIFDEQTDRYDIRFDIADYYGGLHCGECFDVFTGGKW
                     KPTRIEMSAAQEWYLVGIRAEDLNGLRVRI"
BASE COUNT        19576 a        11173 c        15169 g        15466 t
ORIGIN      
        1 tttataatct atatgtgata catattatat actaataaaa taaaaatata tagaaaatcc
       61 ttataaaaat ttaaattgta atggatagta agtaattaaa aagaattttt attgattttt
      121 aagaatttag ttagaaacta tatcattatg gtaaaaaatg tattataatg tttagaaata
      181 ttataataag gggcgattaa acatgaatct atcaaagaaa atagaagata aaagaaaagc
      241 taaacagaga gctgaaaaag ttaagaaagc taaaattgct acagctggtg tagtattagg
      301 agctgttact ggtgcagtga gtggagtact tttggctcct aaatctggaa aagagacaag
      361 agaagatata aaagatgctt cacaacaaat tgctgaaaag ataaatatga aaactgtaga
      421 tgtaaaaggc aaagtatctg agaagctaga gaataaaaaa ggaaacttta tagaatcaaa
      481 gaaaaaaata aaaaaatata tagataacaa aaaaagtgtt gaaaattcta gtgaggaaga
      541 taaaataata gatattgttg aaccagttag tgttactgag gaataatatg aacaatacaa
      601 taacgattaa tataagtata atatatttat tattagctat actcgcttgt attgctttag
      661 tttatttaat tattgtactt gttaaactac ataagatttt aaatactgtt ggaactatgt
      721 taaatgaaaa tactcaaaat ataaatacaa ctttaaataa tcttccgagt gttgtagaaa
      781 attttggcga agtaggagaa aatatgaaag atgtaacaga ggtagttact gaagttacag
      841 cagattttct tgttactaaa gacagtgtta aatcaaatat ggatgttata gttgatatat
      901 tgactataat taaaaatatt tttctagata aaaaataata agtttaatat aaaagaagtc
      961 taagagatat aatttaaacg accttaaaat agtatttata aggtcgtttt attagcttaa
     1021 tttgacacta tgtgttttta ataattggta atattcctct ttatcatttg aacatatata
     1081 tctatgcttg ttgtttcaat tacatccata agaacatctt tacattcaag ctcaaaatct
     1141 tccattcctt ctaaatattc atcatcttca tcaaaaaaga tataagaatt atataaccat
     1201 tcttcaaatt tttcttcaag tatatcccaa tacgaactcc aaaataatcc acaacctgac
     1261 atataagatg ctctactttg atttatataa atctctttta gaattttttg taatctacaa
     1321 ctataaagta aatctgcttt tccattgctt gatattaact catttaaatc ttctattgac
     1381 attaattcaa ctttaccact tttatcataa ggagtataat tttcatcaac ccatttatgt
     1441 ggtttgtttt ctctgcatac tgttgctatt aactctacaa cttttgttct tatcattttt
     1501 tctttatcct gacttattta ttttttataa aataatcata attttataat ttatctattt
     1561 gttttaatgc taatttaaca gtttcatatc tatcagcacc atttattact acatcacctt
     1621 ttacaagttt attagcttct ccgcctacaa cataaacttt tttacctaaa ccttgcttat
     1681 agctagacgc ctcaattatt aaagaatcct tcaattgcca atgtaaaatc tgagcagcca
     1741 ctttatcagc gtcacctgta taaacgatta cattttcata cactttattt acacctcccc
     1801 cttgagaatt tgatatagat ttgtttagta taccttctgc tatcaattta gcaactttat
     1861 ctttattatt aacataataa tctgtatctg ctttactatc tacaaaacat acttctatta
     1921 atattgctgg tgcaatagta tgattaagcc aataaaggcc tctaacatca gactttgcgc
     1981 ccctattttt aaatactgta gccagcctag tgttcactct ttctgcatat gttttttcat
     2041 tattagtctt atatattgtt tctgttcctc ctggagttga agttgtgaca tttgaattaa
     2101 aatgaatctg aacagccaaa tcagtttcct gtttatttgc tatagcacac tgatctgcta
     2161 aatgattact tgattcatca actcttcctg tataaacagt agctccacct attttaagcc
     2221 atttaacaat taagtcattc agtattcttg tttctttact ttcatttata tacccaacag
     2281 ctcctgtacc ttttccagtt aaagtgtgcc ctggtattat tactactttc aaattagcat
     2341 ctcctttaca attaaattta acttctattt aatatatgca taacttagaa ttttgtttct
     2401 ttttatatct tacactttta ttataattta ttttgtaaaa atatagaata ttatttaaat
     2461 agtgttaaag ttataatttt gtatataaga cattactcga ttgcaataat tttatagcat
     2521 actcatctat tctatatcca gttctataat atatatgttt aattccagat tgaattatag
     2581 ccttagtaca gtttaaacaa ggaaagtgag ttacataaat agaacaatct ttaaccgaaa
     2641 taccttcttt tgcacaataa taaagagcat tttgttcagc atgaatagtt ctaatacaat
     2701 gtccatctct catttcatga ccaacttcac tacaatgctt atccccagaa atactaccat
     2761 tatatccagt agacactatt ctgttttctg aattgacaat tatagctcct acataagctc
     2821 tatcacaagt tcctctttca gctactgttt cacacagtct cataaaatat tcttgccatg
     2881 agcatctatt ttcaagtttt ttatccaaat catatacctc caaaatttat atctaatata
     2941 taggatttat accttaaaaa ataatattaa aaacaaattt atatgacaaa taaaatttat
     3001 taatactgtt tttattctaa attattttac tttaagttaa agttacaagg aatctaaaat
     3061 tatatatatt attcttcata atatgaatgt tataatataa aaaactgtct caataaaata
     3121 gagacagttt tacagtcaaa gtttataata caagttcata tttttcttta aattctttta
     3181 ccgcttcagg ccatgccttt tgttctgtaa tacctttttc tttagctatt ttaattgcaa
     3241 tctctcttat cattgcagcg ccttctaata ttcccatttt taatctccct tcaaatatct
     3301 ttttgtatag aatataaata gtgctaagat ttattacatg ctgcatatac agtatctata
     3361 caacacataa cttataaatt ccttttattt tcatacgtct ttaaccgaca tataattata
     3421 ttcaataagt tttaaaatta tgaactcaat tataattatt tttatttttt agaatctaaa
     3481 cactaaaaat tgtaggtaaa tttgtcttat gcctttataa atatttctac agttttaatt
     3541 actggacata tctattttta ttacaaaaag cgcttaaaaa tcgagaatat ccgtataaac
     3601 actgtatata taagcaaagc ggttaaagga aaaataagaa atttacagaa tagttcggaa
     3661 agcccactcc tttagatgtg gtatggatat cataaatagt gtataaaaag tattgataca
     3721 tacacatata atgttaatat aagtatatgg agaataaata tagaaaactc aaacaactgt
     3781 cagtttaatt aattatcact ttgtattctg tcccagatat agaagaaaaa tatttaatat
     3841 agaaggctta gaagatatgt tattcaaaga gattgctatt atgcattttt aataatgaat
     3901 gttaatgata atttaaagtc aatcaacaga gaattgtgtg ttaaaacata tgataacttt
     3961 aaaatattac atgataaaga aataaatagg ttaaaagaat taaaattaaa tggttataaa
     4021 ttaatatcta gtatgaagat ataaaaacta tataggttga gaaacgagcc taatattaat
     4081 gttaatggtg tcgacagata ttttgttaat aaaagtctta ggtaatatga ttagtgagaa
     4141 tatgttgtag gttatgattt attataatta agagtattgt agaacttcat gtagtatcta
     4201 aaaaaaccac acacctttag gcgtgggagt ttcagttgaa tgttaaaatg cgttgcttga
     4261 agcaacaagc agttttgcct ataatatcgg taacaactga aagaaaggtg gttagcccta
     4321 atgttaagcg aaaacattaa aacaatcaga aagtcaaaag gactttcgca acaagaactt
     4381 gctataaaat tgaatgtagt gcgacaaaca atatctaaat gggagcaagg attgtcagtt
     4441 cctgattctg atatgttgat ttctatatca gaggtacttg aaacgccggt aagcacttta
     4501 cttggagaaa ctattgttga gttggaagtt gataacttaa aagtgatttc tgaaaaatta
     4561 gagattataa acttgcaact tgtacaaaga aaaaatatga gaagaaaaat gtttcattgg
     4621 ttatttattt tattatgttc agtcatagta atagttttta tggtcttagg aggactaaat
     4681 agtccttact tgaattggaa ttataccaac cctgaaaccg ctgtttttgg agtagctttt
     4741 catgcgtttg agtgtctatt tgtcagatta acaccgattg tccttatagg ggcgattatt
     4801 ggaagctttt tgacacgtaa gaaaatatga agcaactctg ctttttataa tacagcaagt
     4861 gttccttaaa agcgtcattc tacatgacaa tcgaggacga ctatgtaagg aagaatcttt
     4921 ttgatttcca actaagcgaa gtcattgagg acgacagaag cccaaaaccg tattaagtga
     4981 aagcaagact gctggactta tacgcccatg cgtcagaggc agaagcaaac aaagaaatgc
     5041 taagtctgat agcatgattt gcaacaattt gtacaacgat tacgagtaga aatatattac
     5101 gaaatcagaa aagaaatgac ttgataattt acccatgtta taattattga tgtgaaatta
     5161 ataaattgaa attccttttt ggggtttaac gatactgagt aaggaaaaag tgaatgactt
     5221 ttgcaaggag gtgttgatat cagacaagta aagtcttttg tttttccagt tatatcctta
     5281 atattcttag accaaattag caaagttctt ataggattat tcttaatggg ctttgaaatt
     5341 gatataactg gaaaattttt aagattcaat cctgttcaaa atacaaatct ctcttatgga
     5401 ggaaatttta ttggtattct atctaattta tgggtattgg tattgtttaa cattttagtt
     5461 atcctagtta ttatatctgg atatgctttt tacaaatcaa aaaatgaaca aacgagctat
     5521 tcagtaaaag taattatgtc ttgtggactt gctggtacaa tatgtagctt gatagataaa
     5581 ttattttggg gaggaagttt agattttttg cagataccaa gcttttttat tttcgactta
     5641 aaagactgct atcttactgt tgcagaaata atatttgtta tcataggaat tttacatagt
     5701 agagaaatat caatgaaaga atacatatat ttttgctatc gtcagtttaa aagataattt
     5761 tagaagataa atttaagttt caaggtaaac tatttaatca cagcaaatag ttggctcact
     5821 tcagattttg ggctaaactg tgagcactca ttaggtctct gctatctaac aaacggagca
     5881 caaaacggag tacaaaaatg aaaattaaat attgaatata aaacacagtt aattttgatt
     5941 aaaaagttgg ctgttttttc ttttatagaa atttaagcat aggtaataaa aaaataactg
     6001 tatttatgta taattggagg caataaaaag ccagtaaaac ccataaaata gggtcatact
     6061 ggcaacatgg taagtttata agaagataat caaaaattta cgctttattt taatttaaaa
     6121 aacatactaa aaatctgatt atcccctaga acacagtacc tatccgcata tacacaggac
     6181 taacaaagcc attttactac taatttacta ctaccgaatg agccttgata cgttgataag
     6241 tcctagaaat gcaaaaatac ggtataaaca cctcagtatt gtatcaaata aaactaaata
     6301 tttaatagaa catggaacac gaaaaaaggt gttccttttc tatgataagg aaaccaaagt
     6361 tacacagctt tcccagtttg agcttacttt gcagaaaaat gacaactgga aaataataat
     6421 ggaatagttt ctatgtaaat atatttttac tatcttacct aactaattga aagatgatat
     6481 aatttaatca aatatttggt aaggagggat gaatatgcat ttaattgatt ttatgaatga
     6541 agatattaaa aagaagcttg ttaaaaaaac gtataaaaag aaagagacta ttctttttgc
     6601 tgagcaagaa aatgaatatg taattcttat gattgacggt attgcagaag cattcatctt
     6661 aaatgcgaaa ggaaacatct caactattca tctttataga agtggtagtt tttttggaga
     6721 aatggaacaa tttaatgatg ggaaaaaacc cgttgaaatt gtcgctttca cagattgtaa
     6781 tgtatataaa cttcatagag atgatttttt aaactggcta aagggagatt ttgaagctac
     6841 aaaatttctg attcgagaaa tatctagtaa attagttgta aatgctgaat taattgaaga
     6901 attatcatct ttaagtgtta aagaacgact tctgaagtgt atatccttac actattatag
     6961 aagtgaatta aatctgctta ccaaaaaaca gcttgctagc gaagtaaacg ctccaattag
     7021 aagcattaat cgtgctataa atgaatgtgt acaagaacat ctaattgctt atgaaaacaa
     7081 aagatttagt gtaattaatc agcgagaggt attaaagaat cttcctacaa cataagtata
     7141 atttcaaaaa agcattggat aataattatt caatactttt ttatttcggg tcaagtgacc
     7201 tatttttttt tatttcttca ttatataata ctcctatgca taattatgtt ggattgatag
     7261 ctaataaaag aaagtgagag gtgttatatt atgactaaaa cacaacagga aatgatacaa
     7321 aacgtattag aattttccaa aagagatagt aggataatag gacttgcaat tagcggttct
     7381 tatatcacaa aatcgttaga tgaatattct gatttggatt ttctgattgt agcagatgat
     7441 aaatcctatg aagaagttat cgaagagaga ttacttattg tggaacagtt tggaacatta
     7501 gtttctgctt ttactggcga acacgttgga gaacctcgat tgataatttc cctctatgat
     7561 tcccctgttc ttcatgttga ttttaagttt acaaccttag atggtttact agatagggtt
     7621 gaagattcag ctattctcta tgaagaaaac aactgcataa cagaaattta ttctaaaaaa
     7681 gaagcatact tcccaactcc agacttacag tggattgaag atagattttg gatttgggtt
     7741 cattacgctt gcactaagat tggacgtaga gaactatttg aaacaattga ttttttatct
     7801 tttttaagac aatcagtact tgccccattg atacagcttc tcttaggtaa attacctcgt
     7861 ggagttagaa aaatcgaatt ggatgcaccc caatatattg aagcattaga aaagacggtt
     7921 gctacccatg aatatagaag ctgtgttaat gcattgcagg ctactatcaa cctgtatctt
     7981 gagttaagag aggaattatc acaaagtcct attgtccgaa aggttgaagc tgaaagggtt
     8041 gcattacagt attttcaaga tttaatcaaa taaacccaaa gtaaaaaaac attgaatggt
     8101 aaatattcag tgttttttca tttttggtca aacgacctag attagttgtt gtaaccattc
     8161 tataattatt ttgaaagtaa cagtaaggag gataactatg agtgatattt taagtagaat
     8221 ttcaaataaa attggggata agaatatagt tgataagtta tcagctctat caaaatcaga
     8281 tttgaactca cttctattag aagtgtttga tagacaagca aatactttaa ctgcaactga
     8341 tattctaaag tcataccaac taaatagatt tactatccct agcagtatag atccagaaga
     8401 aattcatact ttggaatcaa aattattgag aaaagcattc aatatggata tcaagacgat
     8461 tatgctttct ccatctgctc cattaggtag ttgtagcgtt tttggctccg tagatcaata
     8521 taacgtagta agtgctctac gagggacaga aacacttgca gacccctcaa atatgttggc
     8581 aataattatt gctgataaat taaaaagaaa agaagaaaat aataccatac ctatccacat
     8641 ggctactact gctagggcaa taagagcaca aaattttgta ggtaaaggtt tatattcaca
     8701 ttttggctta tattgtatgg tttcatctgg tatagataca gggtcttaca cttgtgaaaa
     8761 aatgttgtta gaaaagcact taaactatta taaagatata ttaagtgaaa tagaaaatgt
     8821 tcgtttctct attattctac gcaaaagaaa cggatacaaa gataatgacg gatttttcga
     8881 cagaatggtt gaaactatca aacttatttt tcctaatata gagttatcaa ttcataatga
     8941 tgatgttgat aataattatt ataaaggtat caatttcaaa ttatcggtca aacaaggaaa
     9001 tgataccgtt gaaatggttg atggtggatt tgttgactgg acttatcaaa tgcttggaaa
     9061 taaaaaagaa cgctgtttga taagtggtat tggcttagaa agatttcttg tagctgtttc
     9121 ataaaaggag aagaaaaatg gaacttatag agtggaatta tgcttatatt accgatttag
     9181 ttgagtttgc gaatgataaa gaaattgcaa agaatcttcg tgacaacttc cccaaccctt
     9241 atacggagca aaacgctaga gattttatta gtttttgttt ggcaactcca gatgttaaac
     9301 aacttagcta tgctattttt tatcaagaaa gggctattgg aagtatcagc ctaacatttg
     9361 aagaagatac ctctattaat aaaaatgctg tattaggtta ctggcttgct aggaactatt
     9421 ggggtaaagg gataacaaca aatgcagtaa aagaaatatg caaaattgcc tttgaaaaat
     9481 acaaccttaa caaaattcat gctaatgtat attcctacaa tagaaggtca agtaaagtat
     9541 tggaaaaatg tggttttaag attgaagaat actgtcacaa ttccataata aagaatagaa
     9601 acatgattga ttgccatgta tatagtttaa ttcgaacgca atagcattta aaggacgcca
     9661 ttatcttatg aatattctga acaataagcc actaggtgcg aaaagcattg atatggttaa
     9721 attatcagac gctaaaagct gggctatccg aatgagtgaa gatgggtgtg cttataaatc
     9781 cattgacaat tataagcgtt cactgaaagc gtcgtttttc atggcaattc aagacgacta
     9841 tattagaaaa aatccatttg attttcagtt aagtgatgtt ttggaagata caacagaacc
     9901 aaaaatcgct ctaacaacag aacaggaaat ggacttatta tcctttatgg agagcgataa
     9961 tacttattgt aaatattatg atgatgttgt tatcctctta gaaataggac tactcatttc
    10021 tgaattatgc ggtttgactt tagaattgga tatgaaaaat aaagccatta tggtagacca
    10081 tcaattgttg agtgatacca agattggcta ttatgtagaa gttccaaaga ccacacaggg
    10141 taagcgagaa attccaatga ctgagaaaga gcttatcaat catttgaacg tatcgtggaa
    10201 cggcgtaaga acgctaaagc aaaaccaatc attgttgatg tttatcaaaa cttcttattc
    10261 cttaaacgtg atgggttacc aaagtaagca accaattatc aaagcatgtt aagagcgtta
    10321 gtcaagaagt ataataagac tcatgaggac aagctaccaa agattacgcc acatgattga
    10381 gttataataa ggacaagtta gaaaacccta ggaaatacag ggggttgcac taatttagtc
    10441 cttattttta attccctgaa aaggggataa atgaggcagc gctgtcattc cagaatacga
    10501 attattgtaa gtccagaaca ctggatatgg atttgcatac cacgaaagcg gtgataactg
    10561 aatatactta tttttaggac tgaattagct cgcacggaca ttagttctgg ccgtctggtt
    10621 cagtcctctt ttttatttga gatcaaagaa aggtgataaa gaatatggca aaaattatat
    10681 cagtagtaaa ccagaaaggc ggaactggaa aatccgcatg tgcggcaaat cttggtgtag
    10741 ggttggctct tatgaataag aaggtgttag tcgtggatgc tgatcctcag tcagatgtgt
    10801 ctgctggatt tggattccgt gactgcgata atagtaatga aacattaaca acgctgatgg
    10861 aaatggtgtt gaatgatgaa gatattccgg aagactgctt tatccagcat acagaggaag
    10921 gtattgatat tatctgttcc aatattggat tggcaggaac agaagtacag cttgtgaatg
    10981 caatgagccg tgagtttgtc ctgaaacaga tattaaacag ggtaaaagac aggtacgata
    11041 cagttttgat agattgtatg ccatctctgg gtatgatcac catcaatgcc ctggcagcat
    11101 cggatgaagt attgattccg gtagaagcat cttatcttcc aatcaaagga ctgcagcagc
    11161 tcttgaagac aatcggcaaa gtaagaagac agattaaccc gaaactacag attgccggta
    11221 tccttttcag tatggtggat gcccatacaa atgatgcaag aaacaatatg gagctgcttc
    11281 ataatgcata tggaaatcaa attcatgtgt ttgacaatta tattccattt tctgtcagga
    11341 tgaaagaagc ggtcagagag ggacagagta tttttaaata cgaaccaaaa ggtaaagttg
    11401 cgaaagcata tatgaatttt acggaggagg ttcttgaaca tggcaggtaa aaagaaatca
    11461 acgccaattc cattacagtc attagatgcc ctattcggaa caacaagtga ggaacaggca
    11521 ggcatccaac agattgctct ggataatctg cattccttct ctaatcatcc gtttaaggtt
    11581 ctggatgatg acaagatgat tgagttgtct gaaagcgtga ggacgcatgg agttttggtg
    11641 cctggtattg tgagaataaa ggacaccggc ggttatgaaa ttatagcagg gcaccgccgt
    11701 aagagggcgt gtgagattgc tggtttgaaa accatgccag tcattattaa agacttgaca
    11761 gatgatgaat cgactgtgat tatggttgat tcaaacattc agcgtgaaga actgttgatc
    11821 agtgaaaagg catttgccta taaaatgaaa tatgatgcat tgaaacgcca gggcaaacga
    11881 agtgatttaa cttcttgcca agttggcaag aagttggcgg cagaggatat cagccaaaat
    11941 tcagaggata gcacacggca gattctcagg tatatccatc tgacggaatt acttccggtt
    12001 cttctggata tggctgacca taaacagctc ccgtttaata ctgctgtcga attatcatat
    12061 ttgaaaaaag aggagcagga tatattgctt cagtatatgg gtaaccatga aatggttccg
    12121 tccatgaagc aggcacagga aatgaagaag tgttctaagg aacatttact gacatattcg
    12181 gaaattgatt gtatctgttg ccagggtaaa acagagaaat tacaggtgaa gctgccggaa
    12241 aagaagctcc ggatgttttt tccggagagt tatacaaaag agcagataga agatgtgatt
    12301 tttaaattgt tagaggaatg ggcagacaat aaggagcgtg ttcaaaatga caatcatgga
    12361 tgtgattaag aaggcattgt taccactggc agctatggca ttctggctct ggatggtaaa
    12421 aacgattatg ggagtgaccg ggaatacaga tttatttatg ttcctattcc ttgcagggct
    12481 tccgtttgga atacataaaa tgtgtatcat tttaatcccc agaggctatg atgttggggg
    12541 tactgttgga atgatcgcat tgagtgttat tgtgggtggt ttattgggaa gccttatgat
    12601 cccatattat attgtgaggg caatctatgt gaccatccgg tatatagtaa aaagataatg
    12661 agtagcagat ttgaggcagg cttgcgaaaa aacaaattcg taagcctgcc tttttttgtg
    12721 cgataaagct ggaaagtaca aagccaaaaa tgttttggat ttgtatttga cagctaacgg
    12781 tcattgagca gcaaagctgc gaaatgtgcg ataaagcagg caattcaggg ggaatcccct
    12841 tttgcataaa gaaaaagacg gaggagaacg aacatgagag agcgaatcaa gaacaaacag
    12901 attacgaaag aaatcagagg gcagcttccg gttattgcac cggctatgtt ccgggaaagg
    12961 ggctgttctt attgccctta ttatgcagga agttatgaaa aatttccaag atgcatgatg
    13021 gcatcctgtg cctgggatga tgaagaagaa catttccatc cagttcttcg ccagatgctt
    13081 ccggaattta aaaggaagat ggaaaaagca gaagagaaat atctggaatt aaaaactgcg
    13141 tatgaactgc ttatgagtat gtttgaggct gaaatggcac aggaggaact ggaaaaggat
    13201 gaatgttacg actgttgtta tgccaagtgt ggtccatgta tcgggctgtg ctataaaaca
    13261 ttgaaagaat aggaggatgc gaggtaatga atacagcaat tatttccgga agactggttc
    13321 gtgatccggg ctataacgag acacagaatg agaaaggtct tcataagatt gccaagtttg
    13381 tactggcagt cagaaggaat tactcagacg atgtcagttt cattccggtg aaagcctttg
    13441 caaaaaaagc ggagtttgtc cgtgattatc tggtgcaggg gacaaaggta atggtagagg
    13501 gtgaaatcgt aaccggcagt tacgataata aagagaccgg caaaaaggta tatacgacag
    13561 agctttttgc agaccgtatc gagtttgccg gtgcaaaagt gcaggagaaa atgccggagc
    13621 ctatggaagg ggatggtttt ctgaacatcc cggaatctat ggaagaagaa atgccatttc
    13681 gataggagga taagccaatg gtaatgttaa ataaagagta catgatcaac cacatgagaa
    13741 atgaaaatgg ttccatcaat atcaaaaatg tagtattggc ggctgcctgt gaagcaaccg
    13801 agctgttcca gtgcctgatt gtaatggaca gcaactttac agattggagc cgttttgttg
    13861 accgtctgga gaagaacgtg gaaagacagg actatgaaaa agtccatgaa ctctgccaga
    13921 ccatgtatgc catgaggcat ctgtcagaag aactggaagg tttgtatctg gtaagggatg
    13981 atgcagagct ttgttccctg tattatcaga tttttgtggg aatgctggat ttgactgttt
    14041 tctcaacaga ggcaatggtc gatctgaatg gagggaagca tgatgagtaa tcaggattat
    14101 atgccggtag agtgcctgct ggtgccaaag gcattgttta aggatgcgag atattgctct
    14161 ttatccacta cggcaaaggt attatacagc cttatgcttg accggctgag atatgcagca
    14221 caaaacaaat ggattgacca gaaagggaga ccgtatgtga tctatcccaa aagtgaaatg
    14281 atcagggatc tgaatagcac caggtaccgg atggattatg ctgtttcgga actggaaagt
    14341 atgggaaaca tggttcgggt tgttaaagac aatggcagac cgaaccgttt ctatataaat
    14401 gatatttcaa agatgaatga ggaggaaaag actatgatga caatcaatga tttaatgaca
    14461 atggtaggcc cggaggaggc agaagaaatc atggacaaga tggtgacagc tgccagggaa
    14521 attgtggatg accttatgaa aaaaggctac atcgagatta taagggaagg ctgtccggag
    14581 ggagggcctc tggaggatgg tgtaccgcca attgatctgg gagaggacga gtttaatccg
    14641 gaagatttaa gtccgatgga attcagatgc tactgtgatg agaacggtaa cctggatgat
    14701 gaggcaatcg aagatgatgc cagtgaattt ggtatggacc tggctttcgg tgtcattgaa
    14761 ttactggaaa atgatccgga tagaattgag gcaatccgcc agtatttcaa ccatgtttac
    14821 aagatggaat ccatgaagag atttatggct gtcgtagaga caacggctgt gatctgcgga
    14881 aattccccgg aatggatcga agatatgcac gcctgcaaca aaggtgccag acgaatctat
    14941 ctgaaggaac tggtgagtgt gttcaacatg tacctgaata tgttcaagaa caaagagatg
    15001 gaataatgag gatgaaaaaa tggattatga atacttccgg gtagaagaat ccgagcagtt
    15061 ttcatttttc cgtattccca aggcactgtt tacagaaaag gaatttgaag ggctgtccac
    15121 ggatgcaaag cttctgtatg gcatcctgct ggacaggatc aacctttcaa agaaaaatgg
    15181 ctgggtggat gctgacggtt atgtgtatat catctacacg gtagctgaac ttcaggaagt
    15241 gctgcacatg tcacacacaa cggtcacaaa gcttctcagg gagcttgaca gtgtacatgg
    15301 catcggtctg atcgaacggt accgacaggg ctgcaaccgt ccatcggtga tatatgtgaa
    15361 gaacttcgta aaacgcatcc gggcaaaacc ggcagtttat tatccttctg gaacgcaaga
    15421 aatttgctgt ccggagcgca agaatctgga agtccggagt gcaaaaaaat tgcagtccgg
    15481 aacgcaaaaa attggaagtc cggaacgcaa aaattttgcc acaaataata ctgatataaa
    15541 taagactgat aagaatgata ctgacaggag taagagccgc tcttcggaaa aggaaagcac
    15601 atgtctgtac ggacggtttg gaaatgtccg gctttccgtg gaagaaaacc gggagttgcg
    15661 gaaactgtat ccgtatgact tccagaggat gattgaccag ctttcagctt atatgaaatc
    15721 cactggaaaa acctatcagg atcatttcgc aacgattctt ctctgggcag gaagggaaga
    15781 actgaaaacc ggttctggaa gatatgactt tgaggaagga gagagtctat gacagatagc
    15841 aggaatgtgg ctgattttct tggggaagac ggatgcctcc ggtgtggtgt atgcgggaaa
    15901 cggaaacagc tgaggattaa ttttatggga agggaccgtg tagtgggctg cctgtgtgac
    15961 tgcgaggctc aggcaagaaa agaaaaagaa gagcagctcc gcagggaaga agcccagagg
    16021 gagctttacc agagaaaatc ggtaggactt agagaccgga ggttctggga atggcgattt
    16081 gaaaatgata atgggtcaaa tgataagatg ctcattgcca ggcagtatac aaaaaactgg
    16141 gagaagatga aaaaagaaaa tgtaggcctt ctcctgatgg gtccggtggg gactgggaag
    16201 agtttttttg ccgggtgtat tgccaatgcc cttctggaac agggggagcg ggtgatgatg
    16261 acgaacttct cacgtatcct gaatgaaatg acaaactatc aggcagataa aaaccagatt
    16321 gtgcagaatc tggtggatta cccgcttctg attattgatg atctggggat agaacgtaat
    16381 tcagagtttg ccctggagca gatctataac gtgattgaca gcaggtactg taaaatgaag
    16441 cctctcatca tcacaacaaa tctcgggttg aatgatatga aagatgaagc gctggatgta
    16501 gcccataagc ggatttacag cagaatattg gagatgtgtg tacctgtcta ttgtggcggg
    16561 gcagacaaaa gaagggaaga aggaacggaa aagctcggtc ggatgcagag tctgatcagt
    16621 ggttgatcgg ttcttttttt gatgaaaggg gtgataccaa tggtcttagg ttgggacagc
    16681 aagtaatacg ctgaaaggag ggaaattcat gcaggaagaa gtaacacaga aaacggtgac
    16741 tttttgtgtg cgtaccacaa aaatgacggc agatgtgctg aaaaaagtga ttgccgcata
    16801 cctgcggcat cagaaacaga aaagtgctga gaagaaagca cagaaaaatc agccgaaaca
    16861 ggggaaaatc acggtgaaag agctggcaaa gcagaatgcc gggatgacga atattgagat
    16921 cacacccaag aacatcaagt cttttgaacg gtatgccaga aaatacggga tcaattatgc
    16981 cctgaaaaag gataagacca aagatcctcc ggtttatatg gtgttcttta agggacgtga
    17041 ccaggatgcg atcaccgcag ctttccgtga attttcccag aaagagatcc aaaaggcgaa
    17101 ccgcccttcc atacacaaac gtctggcagc atacaggagt attgttgcag ggaagacgaa
    17161 gggcaaagcc aggaataagc atcaggaggt atcccggtga gaaagcttac tgccggtggt
    17221 atgactaaca agctgaaagc aaaagccaga gttacgctgt ccgctttgga tatgaaaaag
    17281 cttattctca ccaatcttcc gtacctgttc atctttttgc ttgcagacag ggcatcctgt
    17341 ctgtaccggg caagtcccgg ggcagatatg ggaaacaaac tattatatgc catggaacat
    17401 gctgaccgga ttttgaccgg gttcctgcca agtctttact acatggatgt tctggtgggt
    17461 gccgggattg cggcagttgt gaagatactg gtctggcaga aacaggcaga tgcaaaaaag
    17521 ctccgcaaag gcgtggagta tggctctgcc aggtggggaa cagcggaaga catcaaacca
    17581 tttatggcag atgatttctg gatgaacatt ccgctgacgg caacggaatc cattaccatg
    17641 gagagccgtc cgaagaaccc aaagtttgcc agaaataaaa acatctgcgt catcggcggt
    17701 tccggcagtg gaaaaacaag gtttttcgta aaggtctcta ttatgatgat gaactgttcc
    17761 atggtcatca cggatccgaa gggaacactt atcgaagaat gcgggaagat gttagccaaa
    17821 ggaccgccaa agagagacaa gcatggaaat gttgtgaaag ataaatccgg gaaggtggtg
    17881 catgagcctt atgtgatcaa ggtcctaaat accattaact tctctaaatc gcttcattac
    17941 aatccgtttg cctatttaaa atccgaaaag gatatcctga aactggtgac ggttatcatc
    18001 gccaacacca aaggggaagg ggaaaaggca accgaggatt tctgggtcaa agcagaaaaa
    18061 ctgctgtaca cggcactgat tgccctgatc tggtatgaag gggacgagga cgagaagaac
    18121 atgaacaccc tgatcgacct tctgaatgaa agcgagacca gggaggatga cgagaattac
    18181 aaaaatccag tggatatgct gtttgaggat ctggaaaaaa ggaatccgga acactttgcg
    18241 gtacgccagt ataagaaata caagctggcg gctggtaaga cagcaaaatc aatcctgatc
    18301 agctgtggtg ccagactggc tccgtttgat attgccgagc ttcgggagat catgagctat
    18361 gatgagatgg aactggataa ggtgggagac cggaagacgg cgctgtttct gattatgtca
    18421 gatacagata ccacctttaa ctttgtgatc gccatgctgc agtcccagct tttcaacctg
    18481 ctctgtgata aggcagatga tcaatatggc ggcaggctgc cggtccatgt acgggttatc
    18541 tgcgatgagt ttgccaacat cgggcagatt ccacagtttg ataagctgat tgccactatc
    18601 cgaagcaggg aaatctctgc ttctattatt ttgcagtcgc agagccagct gaaggcaatg
    18661 tacaaggata gtgcggatac aattctgggg aattgtgaca cgatgttgtt ccttgggggc
    18721 aaggaaaaga ccaccctgaa agagatgagt gagcttctgg ggaaggagac gattgacctt
    18781 tataacacct cggaaacacg cagcaaccag aagtcattcg ggctgaatta ccagaaaacc
    18841 gggaaacagc tgatgacgga ggatgagatc gcagtcatgg acggcgggaa atgcatcctg
    18901 cagatacgtg gtgtccgtcc gttctattcg gacaaatacg atataaccaa acaccccaat
    18961 taccggctcc ttgcggatta cagtgagaag aaccggttta aggtggaaaa ggaactggat
    19021 ccgaagtact caccgaaacc tgatgatgag gtggaagtga tggaaatgga tctttcagaa
    19081 gacgggaatg agcaggaaaa taatgaggaa aggaataact aacagggtgc gccggtattg
    19141 ttaccggcgt ttttcattcc cggttacacc cggcaaagtt agttttggtg atttatatgg
    19201 cattttttac cagtgcaatt actactctga agaccctggt cgtagcaatc ggggcgggcc
    19261 ttggcgtatg gggtgtcatc aaccttctgg aaggttatgg gaatgacaac cccggcgcaa
    19321 agagccaggg aatcaaacag ctcatggcag gagctggaat catgctgctg ggaactaccc
    19381 tgattcccca gctggcaacg ctgttcggtt aatggggtaa tggatgaaca ccattatcga
    19441 acgaatcacg gaagccatca aggagatcct catcgggatg atccagaatg gtctggaagg
    19501 gatgttcgtg gaggtcaatg ataaggtggg aacgattgcc agtcaggtag ggcagacacc
    19561 gcagggatgg aacacagggg tttttaacct cattcaaaac ctgtctcaga cggtgatcgt
    19621 gcccatcgcc ggtctgatca ttacgttcgt gctttgttat gagctgatca cgatggtcac
    19681 acagaagaat aacttccatg agttcgaaac ttacaacatt tttctctgga tctttaaggc
    19741 atatgtggcg atttaccttg tgacgaacac atttaatatc acaatggcgg tattcgatgt
    19801 ggggcagcac atcgtaaacg gtgcagccgg tgtgatctcc ggaagtacgg cggtggatgc
    19861 ttctgccgcc attgctaccc tgacggaatc tttggaagaa atggagatcg gggaactgtt
    19921 tttgctggca atggaaacac ttctcatcag ccttaccatg agcatcctct ccgtgattat
    19981 cacggtgatc atgtatggca ggatgattga gatctacctt tatacttccg tggcaccgat
    20041 cccgtttgcc accatgacca ataaggaatg gggcaatatc gggaacaact atctgaaagg
    20101 cttgttcgcc ctggcatttc agggattctt catgctggtc tgtgtcggta tttattccgt
    20161 attggtcaat gcgatgacca tatccacgaa cctgcatggg gcaatgtttt cagtggcggc
    20221 atatacggtc gtactggcat tttcactgtt taagaccgga agcctcagta aatcaatatt
    20281 caatgcccac tgatgggcag gaaaagaaag gagtactacc tatggcgtat gtaccagtac
    20341 caaaagacct taccaaggtc aagacaaaag tagcattgaa cctgacaaag cggcagctga
    20401 tctttttttc gcttgccgca gtagtgggag tcccgttata cctgctggca aagaaacccc
    20461 ttggttccag tgtgtcagcg atccttatgg taactgtcat gctgccattt ttctttatgg
    20521 caatgtatga aaaagacggt ctcccttttg aaaaagtgat gggaaatatc atccgccaga
    20581 aattcatctg tccggcgaaa cgtccgtaca agacggagaa cttctatcag gcggtggatt
    20641 ccctcgtaaa gaaggagggc gtgccggatg gcaaaaaaga agaaacaggc acagcagcag
    20701 tgcctggaag cggcggcaag aaaaaaccgt caggaaagaa gaaaaagaaa cgacaaaaag
    20761 gaaagggaaa aggaaaagct taggaaaaaa caggagaaag aaaggaaacg gcagaagaac
    20821 attccccata ctgcccagca gagcatccct tatcagcgga tgtttgcgga tggcatctgc
    20881 caggtatcga aaaacttttt ttccaaaacc gtacagtttt acgatatcaa ttaccagctt
    20941 gccctgaatg aggataagac cacgatcttt gaaaactact gtgatttcct gaattacttt
    21001 gactcgtcca tcagtgtgca gctgtctttt atcaaccagc aggtggatgt ggcagagttt
    21061 gaaaagagca ttgatatccc ggaccagaat gatgatttca acgagatccg ggaagaatac
    21121 cggacgatgt taaagaacca gctttccaaa gggaataacg gtctggtgaa atcaaagtat
    21181 attacgttcg ggattgaagc ggagagttta aaggtggcaa gaccgaggct tgagcggatt
    21241 gaggcggata tcctcaacaa ctttaaagtg cttggggcac aggctcatcc attgaacggg
    21301 gtggagcgtc ttgagatcat gtaccatgtg ttcaatcagg accggatcga gccgttccgg
    21361 ttcaattaca agatgcttcc acagacggga cttaagacaa aggattttat cgcaccgaca
    21421 tcctttaatt tctcaaagaa ttcctctttt atgatgggaa aaacactggg aagcgtcagc
    21481 tacctgcaga tcctcgcacc ggaactgact gaccgtatgc tggcagattt tctggatgtg
    21541 gatgagagca tcaatgtgaa tatccatatc cagtctattg accagacctc tgccatcaag
    21601 atgatcaaga gtaaaatctc tgacctggac aagatgaaga ttgaagagca gaagcgggcg
    21661 gtgcgttccg gctatgacat ggatgtgctg ccatctgacc ttgtgaccta tggggaagaa
    21721 gcgaagaacc ttctggaaga cctgcagtcc aggaatgaga ggatgttcct tgtcactgtc
    21781 cttgtgatga atacggcaaa gaaaaggcag aaactggaca acaacatttt ccaggtgcag
    21841 ggcatcgcac agaagtataa ctgttccctg cgtcctttgg attaccagca ggaagcgggg
    21901 ctgatgtcct gtatcccact gggagtaaac agaatcgaga tccagcgtgg gcttaccacc
    21961 tcggcaacag cgatctttgt gccatttacg acacaggaac tgttccagga aggggaagcc
    22021 ctttattatg gtctgaatgc gttgtccaac aacatgatca tggtggaccg gaagcggctt
    22081 aaaaacccaa acgggctgat cttaggtaca ccgggttccg gtaaatcctt ctcagcaaaa
    22141 agggagatta ccaactgctt cctcattacg gaagatgaca ttatcatctg cgacccggaa
    22201 gcagagtatt acccgctggt gcaggcactg catgggcagg tagtccgtat ctcaccggta
    22261 tcgacccagt atatcaaccc gatggactta aaccttaact attccgagga ggataatcct
    22321 ttatctctga aatcggattt tattttgtct ctttgtgagc tgatcgtggg aggaaagaac
    22381 ggtctggaac cggtggaaaa gaccatcatt gaccggtgtg tgcgtcttgt gtatcaggaa
    22441 tatctttccg atccggtgcc ggagaagatg ccgatccttc aggatctgta tgacctgctc
    22501 cgggggcagg atgaaccgga ggcacagcgg ctggcaaccg cactggaaat ttacgttacc
    22561 ggttcattga atgtgttcaa ccaccggaca aacgtggata tcaatagccg gatcatctgc
    22621 tttgacatta aggagttggg aaaacagctg aaaaagatcg ggatgctcat cgtccaggac
    22681 caggtttgga acagggtaac ggtcaaccgt tccgcccata aatcgacccg gtactatgtt
    22741 gatgaattcc atctgctttt aaaggaagag cagacggcag cctacagtgt ggagatctgg
    22801 aagaggttcc gtaaatgggg aggtatcccg accggtatca cccagaatat caaggatctt
    22861 ctggcaagcc gtgagattga gaacattttt ggtgcgacac gttgacgcac aaacatcgct
    22921 ctatgagggt aaaacttcat agacttatgg ccatgcgatg ctaaaatcgt cgggcttact
    22981 tccatacgag gtaagcaaca actgataatt cgaaaggtag aatgatgggg taacgccctg
    23041 aaatgccttc tctgatactt cgaccggctc tgactgtaat ggttggggtc tggagctcga
    23101 taaagtcggc ggaagtctgc cgaaacagtg tagaaataca gctgtcgaaa gtgcggtaga
    23161 ggtaccgtat gcagatgaca cgtcgggagt ctataaaata tctatggtga gaatgtccac
    23221 gacggactga cgaaaaccgc gaatgtacgg gtctagatgt ttaccatata gaaatgtatg
    23281 gacacttaat tgtgggtcag tgcggtggag taagaatcga aaatatgaaa ctccgtattg
    23341 tgttataggc acaatcaagc tgacaggact atagcggaca cctaaggata tatgcacaga
    23401 tagaattatc ggaacgtgga aaggtacaga gttgctcata agcaatctgc ggacgaatca
    23461 tataagccgc ttaatctgtg ctgaaaagcg aagctcgaac ctatgacagc cctacgaaaa
    23521 aggcgggctc gaggaatggg ctttagtcgg ttagaaacaa ttattgtcat tcaatcttat
    23581 aaggattacg agtatgacaa aaagggacac tttcccaaga aaggagagtg atgccttatg
    23641 accatgaaaa agaaaaagca actgctatgt gaagataatc tgcgtcacaa cgagtattac
    23701 ggaatgcaga atacgattga taatctatac caggcaagtt tgaacggaga agttttcaca
    23761 gatttaatgt ctgtcatcct tcaaagggaa aacattcttc tagcgtacag aaatatcaag
    23821 aaaaatacag gaagtaaaac aaatggcaca gacaatctca caatcgagga catcggaaga
    23881 tgctcccccg atgaagttgt tgaaaaagtt agatttatta ttaatggaag tgaacatggg
    23941 tatcgcccaa aacctgtaag gcgtaaggag ataccaaaac catacgaccc aagtaagaca
    24001 agacccctag ggatcccatg tatttgggac aggcttgttc aacaatgtat caaacaggta
    24061 atggaacccg tttgtgaagc taagttcagc aagaacagct atggattcag accgaaccat
    24121 tcggtagaga atgccatagc aagaagttat cagctgcttc aacatgccaa tcttcactat
    24181 gtcattgaat tcgatataaa aggattcttt gataatgtga atcacgccaa gctgatacga
    24241 cagatatggg ctatgggtat tcatgacaag aagttgattt ttgtcataag acgaattctc
    24301 aaagcaccta tcaaactgga ggacgggact tttatcacgc ccgacaaagg aaccccacag
    24361 ggaggtatca tatcgccact cctggctaat atcgtgctta acgaattaga ccactgggtg
    24421 gaaagtcaat ggcaatggtg tccgatttgc aaacggaata ccagacccga caatggctat
    24481 cgacaggcta agaaatctaa cctgaaggaa atgttcattg tccgctatgc agatgatttt
    24541 cgaatctttt gcaggactaa ggactctgct gaacgcacca aatgtgcagt cactctgtgg
    24601 ctgaaagaaa ggctcaaact ggaaatttct gaaaagaaaa cgaggattgt aaatgtaaga
    24661 aatcattatt ctgattttct cggattcaaa atgaaagtgc acaggaaggg caacaaactc
    24721 gtggttatat ctcatatcgc agataaaaat ctggagcaca aaagggagaa gctaaaagaa
    24781 caggcaaaga gaattgctca ccctcgcaaa atatatggcg aacagggtga aatcagactc
    24841 tataacagta tggtcactgg catgcagaat tactactgta ttgccacaca tgttaatcat
    24901 gattgtgctt cccttaaccg cacagtcatg accttgctga caaacaggct tagcactcgc
    24961 acaggcaacc gccttgtgaa aacagggcga gagcttacgg agtttgaaaa agcccgtttt
    25021 ggtaaatcca aaatgatgcg atatgtcgct ggtacgaatg agcccgtgta tccaatagga
    25081 tacacacagc acaaaaatcc gcttttccgt aagaagagct ggaattatta cactcccgaa
    25141 ggacgtgaag gtattcacaa ctgtctgaga atcaacatcc ctatgatgtt ggctctcatg
    25201 cgtcaaccag tctattccaa tagtgcggaa tacgcagaca atcgaatatc tctcttttca
    25261 gcccaatggg gaaaatgtgc tataaccggt gttgaattct cctctgttgg ggaaattcat
    25321 tgccatcata agttacctcg acatttaggc ggtacggatg cctatgagaa tcttattctc
    25381 ataaagaatt ccgtccataa actcattcat gcttcaaaag cggaaactat ttacaaatat
    25441 atggatttac tacagctaga taacaaacag cttataaagg ttaaccacct tcgtgagttg
    25501 gcttccatgc aacctattta atcttatttc aactactaca gtttttattc tattcaaagg
    25561 ttgattgttt agacaatgaa aaatactaac cgatggaacg ccgtgtgcgg tgaaagtcgc
    25621 atgcacggtg tggagtgggg gaaaagcccg agatgatatc agaggcttac ctatcactat
    25681 agaactcgga tttcatttac atgctcaacc aggcatccgg tgaccggcag atcctggcaa
    25741 agcagctgaa catttcaccg acccagctgt cctatgtgac gaacagcaat gaaggtgagg
    25801 ggcttttgtt ctatggaaat gtcatcatcc cgtttgtgga caggttcccg aagaacaaac
    25861 tgtatcagct attaaccacc cgtccggaag agacgggaga tcaggcatag gaggaaaaac
    25921 gatgcatgta ttagcatatt ttctgacatt tacagcaggt atggtatgtg gtctggttct
    25981 tacctgtatc gtgcatgcag gaaaaaaatg aaggaggtaa cagatggcag aacagagaat
    26041 gaaagccagg gagaaaactg tccagaagat gacaaaggac ggtttagtgg aagaaaacct
    26101 ggcagataaa tccactgttc gtgtcagcag ccgtacccgg gatgtgcaga tgtcaaaaaa
    26161 ggataccgga aaagggatgg atctttccaa ccggagaggg acgagagagg acagtacgga
    26221 tccggtcagg cattctgtgc agaactccag ggatgcaccg gcaaaggcac agacagtaga
    26281 caaagcaaaa tcccggaaaa tgatccggga acaggcagag ggcagttcca aactgtcact
    26341 ggaagagaag aaaaacggca gtgggaaact tcaggagaag catacagacc ttgcccagtc
    26401 aaggggagat gcgaggaaga aacagaacgg aggaagtaaa aagccggggc agaagcagag
    26461 gctgaagttt gcctatgagg agacggcgga ggcagtcagg gatggtaatt cttcagctaa
    26521 actgaaccgg atggatgcgg acggggtaaa tttccgccat gatgcccaga agaaacggaa
    26581 ccagaagatg gctcacacgg aggcagaaag gaagaacgca ccaaagaagc attccatgaa
    26641 agaaaaggtc tatcaggaaa atgcagaaag tgcaggggcg aaaaagaaaa gccggctgaa
    26701 atttgaaggg gaaagcccga aagatacttc ccttgtcaaa aaggcaggca ccgctgcggc
    26761 agtatctgtc catcgccagg tcagaaaaaa tgatgatggc aatgcggcgg tggaaggcgc
    26821 aaacagttta gcagaaggtt cagaggggct ttaccatctg gaacagagaa gtgccagaag
    26881 gcggaaccgg agaaaaagcc ggtcaagtgc ttatcaggca aagaaaacag cgcaggctgc
    26941 ggcagaatct tccataaacc aggaacggtc ttatttgaag aagctgatcc agaaacaacg
    27001 gatcaaaaag gaatattcca aagcaaaaca gagtgagcag gcaatgggga ctgcagcggt
    27061 cggcacgatt gactatatca agaagatcgg cggcaaagtt accaactttt tcaaggaaca
    27121 ccggaaggta tatatcagca tcgctgccct gatcgggatg atgttcctca tcatgaccag
    27181 tgtaacgtcc tgttcctcgg catttatgca gagcctgatc aattacaccg gaaccagtta
    27241 tatctcttcg gatgaggcaa tccggcaggc agatctttac tacacacagc tggaaacaaa
    27301 cctccaggag aggatcaacc agatggaatc ggaagagccg ggacatgacg aataccggta
    27361 caatatcgga ccgattgagc atgacccgtt tgttttgatc agctacctgt ctgccaagta
    27421 tgaagaattt acctttgagc aggtcaagcc ggaactggac aggctgtttg cactccagta
    27481 ccagctggag acagaagttg tgaatgagac tgtgacagag acaacgacgg tccgggtagg
    27541 ggaatccctt ggaaatgttg tgacgagcgg ttactgcaac tgcccgatct gctgtggcat
    27601 atggtcagga ggaccgacgg catccggggt gtacccgaca gcgaaccata cccttgcggt
    27661 agatgcgtcc aacccgtttg ttccaatggg gacaaaggtg gtcatgaatg gtgtggaata
    27721 cacggtagaa gataccgggg catttgcccg ttacggtgtc cagtttgatg tgtattatga
    27781 cagccattcg gcggcatccg cacatgggca tcagacctgg gagtgtttcc ttgcggatga
    27841 taacggaagc cgggaggtgg aagtgacacg taccagggat gtggatgttt tgaatgtgac
    27901 gttaaattcc ggcagcctga caggcatctg ccagagccgt ctggggattt tccagaggga
    27961 actgtttgcc gcctataacg aaacaaaggg caacctgcag atgttcggga caccatttga
    28021 tttcaactgg tattacaacg taagcagcta ttacggatac cggatccatc caatctccgg
    28081 tgcaaaccag ctccacaatg gagtggatat cggagtgccg gaaggtacgg aggtactggc
    28141 agggctgacc ggtacggtaa caacttctgc ctataatgac agctatggca attatgtggt
    28201 gatcaaagac agcaaaggct atgaactgcg gtatgcacat ctgaaaagca gaagtgtttt
    28261 tgcaggggct gccattacca agggggatgt gatagggctt gcaggaaata ccggcaattc
    28321 cacaggaagc catctccaca tggaacttct caaaaacggg gaacgcatga acccgatctt
    28381 ctatctggaa acaggggaag gaaccatttt tggtggaaat gagtacacca gtgaagcagc
    28441 acagaggcta ctgcaggaag cagccagata tctgggaacc ccgtatgtat ggggcggata
    28501 ttccccaagc gggtttgact gttccggttt tgtaagctac tgcctgacca attcaggggt
    28561 aaggaatacc ggaaggctga ctgcccaggg gctttatgat atctgtacac cggtatcaga
    28621 gtccgatgtc cagccgggag atttgatctt ctttaccgga acctataatg caggtgtgcc
    28681 ggtaacgcat atcggtatct atgtaggcgg cgggcagatg atccactgcg ggcatccggt
    28741 acagtacaca tccatttatt catcctactg gcagagccat ttttatggat ttggaagatg
    28801 gtaaaaaagg gcggtggtca tgccgcccgg aaaggagcag tatgaagagc cttgaaaaag
    28861 cagttgccga ttatgaaaag gcaaaggaaa aaatggaggc atccagggca cggtatgaag
    28921 cagacctgaa gcggtttaag gctgcggaag cggcaaagac agaagcggag aacttggaaa
    28981 tcgtgcggat catccgtggc atggatatga ccataccgga actgaatgcg ttccgggaga
    29041 gaatgaaaac ggaactgccg acactggcag gattccagaa ggaggaaaca agagctgatg
    29101 atgaatttag agaaaatgaa agaacagagg gcaccgggca ggcacaggaa atggggcagt
    29161 aacgtaaaaa gaggcgtttt tgcagttacc acatttttat gtatggcaac cccgtttttt
    29221 tctgcccgga gcatttatgc ggcggagagc acaaaccctg ccatcgccat tgaaaagccg
    29281 gacgggtgga aacagggaga tacttctgtt tccattactg tagatgccag ccagatgggg
    29341 gaaggcttta aagtcgcaaa aatcgaagca aagactggga aagatgggag ctggcaggac
    29401 gttacggagt ccagaagcat taccatcaac ggaaaccaga caatctatgt gcgggtgacg
    29461 gatgcagaag ggacggtgta tgaacagaac cgttccatcc gctgttatga tacggaaaaa
    29521 ccaacgcttt ctgcctccct tacggatggt gtgctgacca tccagggaaa tgatgcggta
    29581 tccgggatct ctgcggtaac tgtcaacggt actacctata cggaactttc ggatggaaaa
    29641 ctgaaggtcc agcttacaca gaaagatttt accacaaagc agatcgagat cacagtgacg
    29701 gatggtgccg ggaatacttc cgataagtac actctccaga acccgtatta tgaatgggcg
    29761 gtacgtcagg cacaacagca aagtacagcg aacagcgata tgagtaccac tggcagtgct
    29821 gccacaacgg aagaaacggc cacatccccg cttccgcagg acgcacaggc atcggaaccg
    29881 acggaggcaa ggggaaccgt ggatgaccgt actgtgacgg ggattgaaga agaactggca
    29941 gcatccgggg aagatgcaga aaacattaca cagacagcaa cggaagggac gaaagagttt
    30001 tacaccattt ccaccaaaag cggcaaggtg ttttatctgg tcattgataa ttccaggtcg
    30061 caggacaatg tgtatttcct gacggaagtc agtgaaaaag acctgatgaa cttcacactt
    30121 tccgatacgg taacgcttcc ggaggtagat actgtgtatg cagaaccgga aacagaggaa
    30181 ccggagccga cgcaggagcc ggaagaggaa gagcaggaaa cagaggaagt gcagatgccg
    30241 gaggataaat ccccggttgg ttcctatctt ttgatcgggc tggcagctgc cggtgcgttg
    30301 ggtgccggat attacttcaa ggtctataag ccgaagcatg aatacgatga tgaggatgaa
    30361 tatgaggatg atgagtccga agaagcggaa gaacctgcgg aaccggatga tgcggaagaa
    30421 gagacacttc cggatgaaga ggatccagag gaagtcctgg aagatgagga ggaatcataa
    30481 tggggtgttt tgatgcagat gaaaaaatat ccggttatct atgcagatcc gccgtggcag
    30541 taccgtgtgt attccaaaaa aggattaggg cggagtgcag agagccatta ccccacaatg
    30601 gggattgatg agatccgtgc cctgccggtg gcggagctgg cagaaaagga ttgtgccctg
    30661 tttttgtggg tgacgatccc gtgcctgctg gaagggcttt ccgtcctgca ggcctgggga
    30721 ttccagtata agaccattgc ttttgtctgg atcaagcaga ataagaaagc ggacagcctg
    30781 ttctggggaa tgggttactg gacaaggagc aatgccgaat tctgtatcct ggcaaccaga
    30841 ggttcaccga aacggcagtc tgccggagtc catcaggtga ttgtatccca catcgaggaa
    30901 cacagcaaaa agccgcagga agcaagggag aggatcgtgc agctgatggg tgatgtgccc
    30961 cgcattgagc tgtttgccag gcagaagacg cccggatggg atgtctgggg gaatgaagta
    31021 gaatccgata ttgatatgga aagcagaaag gatgagtgag atgaagttag taatagcaga
    31081 aaagccgtct gttgcgatgg ctctggcaaa ggtggtcgga gcaagggaac ggaaagatgg
    31141 atatgtggag ggaaaggagt atctggtttc gtggtgtgtc gggcatctgg tagcattctg
    31201 tgacgcatcg gaatatgatg aacgttataa aaaatggaga tatgaagacc tcccgatcat
    31261 accggaagaa tggaaaagga aagtccttga cgggacaaag aagcagttcc agattttaaa
    31321 gaaactgatg aacagcaaag aagtggatga ggtcatctgt gccacagatg ccggaaggga
    31381 aggggaactg atcttccgtt ttgtctatga gcaggcagga tgcaaaaagc cggtcaaaag
    31441 gctctggatc tcatccatgg aagaacgtgc aattaaagaa gggtttgcat cgttgaaaga
    31501 cggttcgtgt tatgaagacc tttatcagtc agccttatgc agggcaaaag cagactggct
    31561 ggtgggaatc aatgcgagcc gtcttttttc cgtcctttac aaccagaacc tgaaagtggg
    31621 cagggtgcag accccgactc ttgccatgat cgtggacagg aaccagaagg tgaaggagtt
    31681 tgtaaaagaa aaatactatg tagcccactt aacattcggg gagtttgatg ctgtctctga
    31741 gcatttccag aaaaaggaag aagcggatca ggtggctgcc gactgcagcg aacgcatgtg
    31801 ccaggtggag aaagaagatg tgcagacgaa aaccgtgcgg gcaccgaaac tgtatgacct
    31861 gacttctctc cagagggatg ccaaccgtat ctttggttac acggcacagc agacgttgga
    31921 ttctgttcag gagatgtatg aaaagaagct ggtgacgtat cccaggacag acagccagta
    31981 tctgacggat gagatgggga acagtacgaa acagcttatt cagttgctgt tatccaggat
    32041 gcctttcgca gaggggattg cgtatgaacc ggatatttct aaagtactga actctaaaaa
    32101 ggtatcagac catcatgcaa ttatccccac ttcggaagtg gagaaagcag accttcagaa
    32161 gctgaaagaa aaggagagga acattctgta tctgatcagt gccagggtac tcaccgcaac
    32221 ggcggatccc tatatttatg agacccataa gtgccagctg acctgcaact tccatacgtt
    32281 ttatttcaat gcaaggaaga caaaacagga agggttccag gcgatagaga agaaactgaa
    32341 acagttttta ggtgtcaggg aaccggaaca ggaagcggaa tttgaccttt accttggaag
    32401 gaatatcggt ccgtgcagca cttctgtttc agaaaacttt acccagccgc cccgccagta
    32461 tacggaagac acgcttctgg cggcgatgga gcgggcaggc aatgaagaac tgacagagga
    32521 tacggaaaag aaggggcttg gtacaccggc aacgagagcc gggatcattg aaaaactcat
    32581 ccagtccggc tttgtaaaaa gggaaaagaa gaatctggtg ccgacagatg cggggaatgt
    32641 actggtcaca gtccttccgg atgagatcaa gtccccgaag atgacagcag agtgggagat
    32701 ggcattaaac catatcgcac aggggacaga gacggcagag catttcttaa atgggatcac
    32761 ggatatgctg ggagaactga tttcccgtta ccattcgatt tctgaggagg aaagcagccg
    32821 ttttccggga acagcaatgg gagaagtgat cgggaaatgt ccggtctgcg gcagtgatgt
    32881 gagggaaggt aaaaagaatt attactgtac cgggcaggaa tgccgctttt ctttgtggaa
    32941 ggatgaccat ttccttgcaa gccaggggaa gaagatggat aaagcaacgg caaaaaaatt
    33001 cctgaagaaa ggcaaagtcc attacaaaga cctggtatcg aaaagaaccg ggaaaagtta
    33061 tgaagctacc gtagaaatgg tagctgacag tgagggaaaa gcacagttta acctgcattt
    33121 cccccagcgg tagttaggaa ccaggcagct aaaaggctgt ctgttttcat ataaaaaatg
    33181 aaagagagga catgatctat gagaagaaca ggacatttaa ggagactcgt atccggattt
    33241 ctggcagggc tgacgatgtt atccacggtg ttatcgccca tgacagccta tgcggcagaa
    33301 cccaaagcgg aagaaaagcc gcccctttat gaagaggtca aggatctgct ggacgaagat
    33361 gaagtggtaa aagccaagga ttttgaaatt actgttggaa gtgaatttga cgtcacctgt
    33421 gattttaccg ggctggagat caaagatgac aaaaaagtaa aagtcacttt tgaggaagct
    33481 aagaatgaag agggaaagga ttttgcttta gaccacgcag acagttataa agccgtctac
    33541 tatgtggagc cggtcaatga agcacatccg aagtaccaga tcagcagaaa cctgatcgta
    33601 aaagaggcgg aaactgaagt gcaggctgct tcagaaggag gcggcgaaga tgccggttcc
    33661 ggcggtacag aggaagcggc agatgatggg gaggcagact cgcagacgtt ttctgcagaa
    33721 gagagtgaaa caacagaaac gtccatggag acggaagctg ccacagaacc agtcacagag
    33781 gctgaaccag aaacggaaac agtagaaagc accgaagttc ttccggaaga ggaactggat
    33841 gcagcactgg aggaaagcga agggcaggaa accgttgact cggagaccgg gctttccgta
    33901 tctgatgtac tggaacaggg cgaagaacag ggaattgata tgctgagcct ggaagaaggc
    33961 gagacggtac agtttcaggc acaggcactg tttgcaagtg ccagatccac gacctccgtc
    34021 agtgtaacca gaggggcata ttattattat gcagattatg gtctgggttc ttacctgacc
    34081 gcaccttata ccgtaaagtt tggtgatgtt actgctactg cctattgcgt acagccatcc
    34141 aagccggggc caggggatgg aacttatacg atcacaaagc tcagtgacgg aaagacttta
    34201 gcgaaagtct gctactacgg tacaaaagcc agcggggatg aaggattttt cgcagaaaag
    34261 catccggatt tttctaccgg aaagcgtttt atcattaccc atctggcagc cgcttatgca
    34321 aatggaagca gtgatgcctt ttccggcacc aactccaccg gacaggcgct ggccatggaa
    34381 ctctataact actgtgtgag ccagccggag atcccggacg tggcgatgtc attttccaat
    34441 gcgaaggtaa aagcctatat tgacggcaat tcccagagaa cggaagagat cacttttaag
    34501 gcagatgcgc ttcagaccat tacgatgaag cttccatccg gcgtgaaatt ccacaacgtt
    34561 tcaaccggaa agaccagtgc ggcaggggca agcgtagaag tatccggcgg cacaaagttt
    34621 tatctttccg cacctctgac acaggcggaa gatgtcagcg gttcctgggc agtgaccatg
    34681 aaaggaagca ttaccaagga ttattccgct tataagatca ccacagggtc atctacacag
    34741 gacctggcac tggtatttgg agaaggtgtc acagatgaga agtatgtaga tttcagtgtg
    34801 gaatgggtca agatggcaaa gattgagatc gtaaagaagg atgccggaag caatgcgaag
    34861 gtagccggtg cagtctatgg catttacagt gatgaagcag ggaaaaacct gatcgcaaag
    34921 atgcctgcaa ccgatgccaa tggtgcatcc agtatcacga ttgaaaagac acagaatacc
    34981 gtgtacctga aagagatttc cgtaccgaat ggctatgtgc tggataccaa agcctatggg
    35041 atcaacctgg tcatcggcgg gactacaaag aaagacgtaa ctgataagga acagtttgca
    35101 gacctgaccg tttataagga aggggaagtg ctgaccggtg cttctgtcac agattccggc
    35161 gtggtgttcc agtacacaaa acagagattg aaaggcgctg tttataacgt gtatgccgga
    35221 gcggatatca aagcggcaga tggaagggtt attttccaaa agggtgccct ggtaaaagag
    35281 gggctgacca ccggtgagga tggcagtgca acccttaaga acctgcatct tggcacttac
    35341 gttgtaacag aaacgaaagc cccggcagat tatgtgtgca aaggggaatc caaaaccgtc
    35401 accttaagct atgcagggca gaacgtggaa gtggcagtag gaaatgtgac ctttgccaat
    35461 gaccgccaga aggcaagcgt atctgtggtg aaacaggatg ataccacaaa gaacccgctg
    35521 tccggaggaa tttacggact gtatgcggca gagaatatcg ctgacgtatc cgggaatgtt
    35581 gtggtgggaa aagataccct gattgaaaaa gcaacaaccg gaaccgatgg caatgccgta
    35641 taccaggcag acctgccgat caaccacagc tattatgtga aagagctgca ggcaccggca
    35701 aattatttcc gaaatagtga ggatgtattc tctttcagat ttcagtacac caatgataaa
    35761 caggcatccg tcgcatttac ccatacgttt gaaaatgaac gtgtcaatgc gacgatccat
    35821 ctggtcaaga aagataaaga gaccggaaga aacacccagg gagacgccgc ctttgaaggc
    35881 gctgtttatg gagtgtatgc cagagaaaac atcatccatc cggatggaaa aaccggcatc
    35941 ctctataaag caggaagcca ggtggcaacc atgacggttg ataaaaaggg tgatgcttct
    36001 gtagtagacc tgtaccttgg aaaatactat gtgaaagaga tcacaccgcc gattggatac
    36061 ctgatcgacg agggtgagta tgacctggaa tgcagttatg agggagacct tgtaaaaact
    36121 gtggagcgca gtacggaatc ttcggaacag gtcatgaaac agccgttcca ggtgattaaa
    36181 gcggcgaaca atggaaagac agacgcagac ctgttaaaag gtgccggatt tactgcttac
    36241 ttaaagagca gccttaagac caatccggac ggcagttacg attttgcatc tgccaagccg
    36301 gtagtactga ccgcagatgg aaagacagag atgtttaccg atgccaaagg ttatgcctgc
    36361 agcatcccgc ttccgtatgg tacttacctt gtaaaggaaa caacaacccc gcacaattat
    36421 aagccggtgg atgatttcct tgttaccatc agtgaaaacc atccggatga gccgcagatc
    36481 tggcggatcc ttctggatga tgaatttaaa gcaaagttaa agatcgtgaa gaaagacgat
    36541 gaaacaaaga gaccggtgct ggtggcaggt acagaattta agatttatga cctggaccat
    36601 aagaaatatg tggaacaggt tacgacttac ccgaccactg ttacccacaa atcctacttc
    36661 acggacagcc agggttatct gattcttccg aacaatttaa gcatcggaca ttaccggatc
    36721 gaggaagtga cagccccgga tggctatacc ttaaaccaga attacgtgga gatcgcagtg
    36781 gattccaata cggcatacca gatggattct gtcagcgggg atgtggtgat tgaagtagat
    36841 tacgaaaacc atccggtcaa aggaaagctg actgtttaca aaaaaggtga gatgcttgct
    36901 ggatttaaca aggattttat ttacgaagag cagttcctga aagatgccgt ctttgaggtg
    36961 tatgcagcgg aggatattta ctccacggac taccagaaag acgcagatgg aaaacggatt
    37021 gtagtctatg caaagaatac actggtgact acgatcacaa ccggtgatga tggaatggca
    37081 gtggcagaaa accttccgct tggtgcttac cgggtagtgg aaaaaacagc ccctgacgga
    37141 tttgtgttaa atccggaggc tgcagaagtt gtctttgtct atgaaggtca ggatactccg
    37201 gtggtagaac aggaagtgac ggtcggtgat gaaagacaga aggtagcgat tacggttgaa
    37261 aaacaggatg cggaaaatgg tgctgttgtg gcaggtgccg tatttggtat ctacaacaaa
    37321 gaggatatta ccgcagacgg caaagtaatt gttgaggcag atacccttct tcaggaaatg
    37381 acttcggatg agaagggaca ggcaggctgt acactggatc ttccgcttgg aagctactat
    37441 gtgaaagaac tgaaagcccc ggcaggttat gtatcttcca atgaggttct gaactttgat
    37501 gcttcctatc aaggacagga tgtggaaacg gttgttttga aagccgtgaa gaaaaaccag
    37561 ccgaccacag tggaaatcac aaaatctgac attactactg gaacagaact ggatggtgca
    37621 agcctgaaag tgctggataa agatgggaat gttgtggatg aatggacttc tgttaaggat
    37681 gccccacatg tgatcaaacg tctggtagtc ggggagactt acacactccg ggaagaattt
    37741 gccccgtatg gatacctgaa agcaacggat atcacgttta ctgttgagga taacggtgat
    37801 gtccagaagg ttgaaatgaa ggatgaagtg ccgaccgggc ttctgatcat caacaaaaag
    37861 ggtgaattcc tggataaagt aacgcttctg gataatgcaa aaggcacggt ggagcatctg
    37921 tttgagtata tcaccggaag ccttaccgaa gttacttttc acgtttatgc cgctgaagat
    37981 atcaaagcgg cagatggtgt cagcgaggat tattttaaag cagatgaact ggtgggaacc
    38041 attaccaccg ataccaatgg tattgcacag cttggggatc ttccggttgg aaaatactat
    38101 gtgaaagagg cagaaactgc ccatggttat gtgctggatg gggagccaag atatgtggat
    38161 ttaagttacc gtgaccagga taccccggtg gtaacgtatg atgaagcatg gcagaacaac
    38221 cgccagaaag tcaaagtgac cgtcctgaaa aaggaaaaag acacggagcg tgtactggca
    38281 ggcggtatct tcggattgtt tacaagggag gatatcaaaa atgccagcgg tgatgtcctg
    38341 ctggaagcag atacgctcat tgagcttaag accacggatg aaaacggtca gattaccttt
    38401 acggcagacc tgccggtaga cggaaactat tatgtgaaag agctgtatgc tccggatggt
    38461 tttgtgacca ccaatgagga acaggatttc atctttgaat atgctggtgc ggatcaggca
    38521 gaggtaagct atgattttac ctttgaaaat gaggctacaa ccgtggaact gacaaaatct
    38581 gtcctgacaa caggggatga gcttcccggt gcccacctga aagtgaccga tgaggacggc
    38641 aatgtggtgg atgaatgggt atccacagaa gaagcccatg tgatcaaaga gctggtagtc
    38701 ggcaaaacct acacaatgac agaaaccaaa cctgcagatg gatatgtaac cgcagaaagc
    38761 atcgaattta ccatcgagaa tactgcggaa atccagaagc atgaaatgaa ggacgatgtg
    38821 acaaaggtac agatcagcaa gacagatatc accggagacc aggagattcc gggtgctaag
    38881 cttacgatcc tggatgaaaa tgaccaggta gtggaaagct ggacttccac agaggagccg
    38941 cattatgtgg agaagctgcc gattggcaga tacacactca gggaggaaca ggcaccgaaa
    39001 ggatttatcc tgacagcaga tgtctccttt gaagtgaaag ataccggtga gatccagacg
    39061 gttgttatga aggatgatac cgcaaagggt aaagtgatcc tgaataaaac agataaggaa
    39121 accggcgagc cgttaaaagg cgtggaattt gaactccgtg acagcaaggg aaaggtgctg
    39181 gagaccttaa agacggatgc tgccggtcat gcggagagca gcctttatga gatcgctgag
    39241 tacaaagacg gtaaatttgc cggtgagaag aaatattatc tggtagaaac caagacactg
    39301 gatggataca cactggatga gaccgagcat gaggtggtat ttgcctacaa agatgacagc
    39361 acaccgattg tggaagtgac ctttgacctg acaaatgaca agccggaagt gccacagaca
    39421 acggaaggta cgccgggaac accgtcagca gataatccga agaccggtga tgagacgaat
    39481 ctctggattc cggtggtact gctggcagta tctgtaagcg gcattgccgg acttctggca
    39541 gacagaagaa agagaaaaag aaaatagaaa ccttatatga gcagggagtc ttgatttgag
    39601 gctccctttt atcatagcaa aatcaagaaa ggacaggtaa agaatatgaa gaaaacaatg
    39661 aacacagtgc aggcagggag agaaatgcag gagagatcat tcaagagaat gatggcatac
    39721 cagaaaaaag cagagcaggc agtcaacaaa aagagaatga accagcacat gatcagaagg
    39781 gggtaattgc gtatgatgaa cagaaaagat ttttttgaat atgtgaagga caatgtgaag
    39841 gactatcttc cggaaaaata tgcggatgcc aatatccatc tgcaggaagt agtaaagaag
    39901 aacgggctga cactgacggc ggtggtcatt cccgcaaagg acaccaatat cacaccgaat
    39961 gtatatctgg attcctttta ccaggaatac cggaacggga aaagtccgga tgcctgtgta
    40021 ggggatgtgg cagacctttg gattgaaaaa atggatacgg acctggacgt tgatgtaaat
    40081 ggcatgatgg attacgggaa tgtcaaggat aagctgcagg tcaggatgtg tgacccggaa
    40141 aagaacaggg aatggctgga agataaagct gtgaccatgc atggggattt cgcagcttat
    40201 tatacggtca acctgtcgga aaataaagac ggcattgctt ctgtttccgt gaccaaagca
    40261 cttttagagg cgtggaagat tgatgtccag acgctccatc aggatgcgat ggcatcagat
    40321 aagaaccgtg gaccggcttt atacgcaata aatgatctga tggaatcctc gattatggga
    40381 gaaaaacccc agaacctgtt gaacggagaa agaagggcag aggaattttt catgcctatg
    40441 ttttgcctga cgaacgaaac aaaaatgaat gcggcatccc tgatcctgca tgaggatatc
    40501 cgaaaacaga tcggggagtt tatgaagggt gatttttata tcctgccttc ttccatccat
    40561 gaaacacttc ttttgccgga taatggagat ttcgatgtga aagccctgaa tgccatggta
    40621 aaagaagtca atgcaacaga agtagcactg gaagatattc tttcggataa agtgcagttt
    40681 tgtgatggca gaacagccgt gatggaaaat gcggagaaac gggaagcacg tctggaaaaa
    40741 gaaaaagcgg ctgcggcaga aaagccggca gagaaaaccg ggattcatgg gaagctggaa
    40801 aaggcgaagg aagagatgaa agccggggat gtcctggtaa agccacaggg taaaacgaga
    40861 gatacggcta tggtaatgta acaataataa gcagagttat aaggggactt ccattgtgga
    40921 ggttccctta tatgaaggag gatgtatatg tcagagtggt gcttatatgg tgatgatata
    40981 agagaaaagt ttgaaagacg gttagaaccg gatagccttg aaggcgagtt aatcaggtat
    41041 aaggaagttt tgggtgaaga atttggactc aaagaacttc tgactattca ggatttaagg
    41101 gtaaaagtat tgatagcgca ggcaatcaac aatgtaccgg aatttttact ggatcagatt
    41161 ggaaaagcca ggaacagtta tgagttccct tcccttgtaa gggaattgga acggattgca
    41221 gatgttatgg aagaggtcgt ggagggagaa ggggaatgag cagcaaaatg aaaaaggaag
    41281 aaagaaaaag gttatccgga tatctccgga aatgcctgga gtcacaaaaa gaccaggagt
    41341 tcattcttca aattccctta aagaggggag catcagaaag tgagaagaaa atacggaatt
    41401 gaccaggtat cggttcggct tgtaaaagaa gcaccgatcc tgagtgagaa agagatctct
    41461 acaccggaag atgcgatccg ggtattggga gataccttta aagactatga ccgggaggtg
    41521 gtaggagtgg ttcatcttcg gagtgacaat gttcccatta acatgaccat catcagtatg
    41581 gggacactga accagtcact ggtgcatccg agggaagtat taaaagcggc gttcttatcg
    41641 aatgccgctt ccattctttt gttccacaac catccaagcg gcagcctgaa accctcgaag
    41701 gaggacattg cacttacagg caggatgcag cagctttgta tgctggctgg gattcctgtg
    41761 attgaccatg tgattcttgg aaatgaccag tcctattttt ctttccggga aaaacagatc
    41821 cttcctatgg agcagattca atactctgtg gatttgaatg atatcaatct gaaagtagca
    41881 gaaaaggaag cagagaatta tggatatgag aaaccacata aaaaatcaat caaggaatcc
    41941 ctggaggaaa accggaaaaa gatcacatcc ggtcagaaaa catccggtgt gaagaaaaaa
    42001 cgggaaacga caatagaatg agaggaggat gaacagatat ggcaaataaa ttgtatgcca
    42061 tggaacagct gacggaagaa gtcgcaaagg acatcgcagc aaagccggaa gagtggatgc
    42121 gttttctgga taccgcatcc cggttatata aatacacctt tgatgaacag ctcctgatct
    42181 ttgcccagag accggaagca accgctgtgg catccatgga ggtatggaat aagcggatgt
    42241 accgatggat caggaaaggc tcgaaaggca ttgccctgat tgattataca tccagcccga
    42301 aaaaccgcct gcggtatgtg tttgatattt cggatactta taaggttcgg aatctgggga
    42361 aagacccggc tttgtgggtg ctgccacagg atgaccgttt tcttgcggca gattatctgc
    42421 agagagcgta tggattggac gaaggagatg gcgggcttgc cggaaccctg catcaggcag
    42481 cacaggaaag tgtgcgggag tggcttccgg atgcgtttga tgaactgaaa caggatgtgc
    42541 aggggacatt tctggaagaa ctggatgagc agaaccagga agtggagttc cgggacctta
    42601 tgacggacag tgtatggtat gtcctgttaa agcggtgtgg gatggatacg gaagagtatc
    42661 tgtctgtgga cagcctgcgg cacatcacag attttaatga tctccgtgtg cttgggcacc
    42721 ttggcacagc ggttaatgag atctgcagac cgattctgat gcagcttgga cggtatgtcc
    42781 ttatggatct ggaaaatgac aggaaaacgg ttgcaaaaga atcggaagtg gtctataatg
    42841 aatttaacac gttaattcgt gaaagtggag aaattacacc agaaccagag atagaagaaa
    42901 acaaggaggt aacagagcat gagagagatc acttacagca ggaacgggga ttatctgatc
    42961 ccggatatca aactggagga gaccagggga accatcggga aatacgggat gatgcggaag
    43021 gaatatctga ggaaccacaa gaaagccaga ttcagcatac tggcactgca gaacaggctg
    43081 gacagccatc tgatgaaagt ggacagcgaa gccagacaga aagtggaaga cctgaccatg
    43141 cagcttctgg agaaagcccc ggcaccggag aaatcagccg acagcatggc atggacccgt
    43201 cacatgaacc agatccgcgc acaggcagag gagatggtgg ttcaggagat tatatacaat
    43261 taagcctgtt ccccacagag gaagaacagt ttggagagat caggaaagcg gcagctgcac
    43321 tcacacagcc agccgctttt tttgtttcgg atgagatcgt ggatgatgtg cttcgtaccg
    43381 gaagcggacg gaagaataca ttattccata tcactgcaaa acttgtggaa ggaattgacc
    43441 atgagaaact gagaagtttt ctcatccagg aatatggtac cggcgggaaa gggtttgagt
    43501 tttccggaca gaaattcagc gtctggtatg acggggacgg tatgcgtttc cgacgtgggg
    43561 aatccgcaag acacaattat gaccgtatgc ttacctggga agaagcggca aaccgtattc
    43621 aggatatgta tgatgcgggg acttatgttt ccaacgtgat tatgcaaaat tccattaaag
    43681 tggaatgtga tgagctttcc agccagctgg cactgcattt ccgggatacc ggggctatca
    43741 ggggaatata cagccataca gaaacgactg aaaggttccg tgcaggtctg gatgatccga
    43801 agcagacaag ggagtattac cagatgcttg aggaactgga gcgggatatg gaacgtcatc
    43861 cggaaaacta tatgaggtac cagatccgga ataatccgat atacaagcag agggtttatg
    43921 accttggaag gacgcttgat tggagtcggc aggaagaaat cataataccg ccggaaatgg
    43981 cttttattac gcaggatgag attgactctg ttttacggag gggtggaaat gtagctggcg
    44041 gtaggagccg tatctatgag tttttcatgg aacaccacga tgaaaaagaa gcagccgact
    44101 tcttaaaaca tgagtatgga gacggaggat gcacaccggg aatccaggga agcgaccttt
    44161 ccgatgagtg gcatgacgca aaagggattc gtttaagcaa aggacagata tccaacccaa
    44221 gcctgacaac actggtcaag tggaaacagg cagcttccag gacgaggcag ctgatccgga
    44281 tggatgattt tttgtcaccg gaagaactgg aaaagtatga agaacggcag gaagcccagc
    44341 ggcttgctga tatggaagag gtaaagcagt cactgggaac agaggaagtt tcggaagagg
    44401 ttgaggaagt tcatgcggaa gaaaatgtgg aagataagcc ggaagaaagc gggcagccat
    44461 taagggcaga agatgtgcag aacctggtct tagtaaaccg ccagtattcc tctgtgagca
    44521 ggacgacgga gtatgacttt acctgtgaga tccgtgggga gcaggatatc ctgcattata
    44581 tggtggaata ccacgatgac ggggaagggt ttaccatcca tacggaaaaa gatgatatct
    44641 gggaaagaat gtctgagccg gaactggaac ggctggagag ggtactggaa cgggaagcac
    44701 tatattttca gtatcatgag gatattgaaa atgcggcgaa cctggaagaa cttcgggaag
    44761 tccaatacag tatcatggaa aatgaatcca tctatttccg gcaaatatcg gaacgtgtct
    44821 ggagtgagta tgggcaaaga gaacgggaat tgtctgttga gataccgcct gtcaattttc
    44881 atatcacgga tgaccagctg ggctatggaa cagcaaagga aaaattcaga gccaatgtga
    44941 tggcaatccg tgttttgaaa aaatgtgaaa gcgagaaccg ttatgcatca ccagaggaac
    45001 aggaaatcct gtcaaactat gttggctggg gaggcttgcc ggatgctttt gatgaaagca
    45061 aagcctcctg gagtgaggag tatcaggaac tgaaagatct gcttaccaaa gaggagtatg
    45121 cggcggcaag ggaatccacg ttgaatgccc attatacaca gcctgttatc atcgagagca
    45181 tgtatcagtt gcttcagaat ctgggatttg aaaagggaaa catcctggaa ccatccatgg
    45241 gtgtaggaaa cttttttgga atgcttccgg acaagttaca gcagtcccgg ctttatggag
    45301 tggaactgga cagcatcagc ggcaggatcg caaaactgct ttatccgaac gctgatatcc
    45361 agatcaaagg atttgaaaag accgattatc ccaatgattt ttttgatgtg gcaatcggga
    45421 atgtcccttt tggttcctat aaagtgaatg accgccagta tgacaagtat cattttatgg
    45481 tccatgatta tttccttgca aaaaccattg accagttacg accgggtggc gtggctgccc
    45541 tgatcacaac caagggaacc atggataaag catcgccgga agtaaggaag tatcttgcag
    45601 agagggcaga gcttctcggt gcgatccgtc ttccgaacaa tgcttttaag gcgaatgcag
    45661 gaaccgaagt cagtgccgac attctgtttt tccagaagag ggagagcatt tccatggaag
    45721 agccggaatg ggttactctt ggagaggatg taaatggaat tagcataaac cggtatttta
    45781 ttacccaccc ggaaatggta cttggaacga tggcagaggt gtccggacct tatggcatgg
    45841 agactgcctg tcttccgctg gaaggggcag acctggcaga acagctggaa gatgctgttg
    45901 caaaaatcca tggaacgatg gttcctgcag taacggcaga aacagaactg gatgagatca
    45961 tggagagcat tccggcagat ccgtctgtcc ggaactacag ttttaccgtg gtggatgacc
    46021 agatctatta ccgggtaaat tccctgatga atccggtgaa gctgccggca accacggcgg
    46081 aacgtgtaaa gggtatggta gagatccgtg aggtggtccg ggagttgatc gccctgcaga
    46141 tggaggaaaa tgcaacaaat gaggcgatac aggagcttca ggtcaaactg aatcaggtct
    46201 atgacgccta cacggaaaaa tacggggtca tcggaagcaa tgcaaacaaa cgggcattct
    46261 ccgatgactc ttcttattgt ctgctctgtt cgttggagga acttaacgaa gatggtacgt
    46321 taaagcggaa agcggatatg tttaccaagc ggacgatcaa gaaagcagtg gctgtgacca
    46381 gtgtggaaac tgcggcggaa gccctgacga tttccctgaa tgaaaaagca agggttgatc
    46441 ttccttatat ggcagggctg acaggtaaga cggaagagaa agttgcagaa gaactgacag
    46501 gagtaatctt tcgggatccg gtcaatggac agtgggagac tgcggatgaa tatctatccg
    46561 ggaatgtccg ggagaagctg aaaatggcaa gaatctttgc agaaaaccac ccggaattta
    46621 ccagcaatgt aaatgccctt aagcaggtgc agccggtaga cctggatgca tcagagattg
    46681 aagtccggat cggtgccaca tggatcgccc cggaaatata ccgggatttt atggtagaac
    46741 tatttgatac cccggggtat ctggttggaa gggtaattga tatccggtat tcggaagcca
    46801 gtggtgcatg gaatatcagc ggtaaaaatg cggacagtga ccggaatgtg ctgaccacag
    46861 caacgtatgg taccagccgg atcaatgcct ataagattct ggaagaaacc ctgaatttaa
    46921 aagacgtacg gatttatgac acaaagctgg atgcagaggg aaatgaaatc cgtgtgttga
    46981 ataaaaaaga aacgatgctg gcaacccaga aacaggatgc gatcaaggaa gcatttaagg
    47041 actggatctt cagggatcag gaacagaggg aaaagctgtg ccggatttat aatgaacgtt
    47101 tcaattccat ccgtcccagg gaatacgatg gaagccatct gacctttccg ggaatgaatc
    47161 cggaaataga gcttcgtccg caccagaaaa atgccgttgc ccatcagctt tatggggata
    47221 atgtcctgct tgcccatgtc gtgggaagcg gaaagaccta tgagatggta gctgcagcta
    47281 tggagagcaa acgtcttggt attgcccaga aaagcctttt tgtagttccc aaccacctga
    47341 cggagcagtg gggcgcagag tttctacagc tttatccggg agccaatatc ctggtggcaa
    47401 cgaaaaaaga ttttgaaccg tcaaaccgta aaaagttctg tgccagaatc gcaatgggca
    47461 gctatgacgc agtgatcatc gggcattccc agtttgagag gatcccctta tcggaagaac
    47521 gccagaaaaa gatcatcgaa gagcagatcg aagaactgga agaaggaatt cagcaggcaa
    47581 agctggaaag tgatggcagc cgttttacgg taaaacagtt ggaaaagacc aaaaagagtc
    47641 tcaggaggcg tctggaaaag ctggagaaca aagagaaaaa ggatgatgtg gtaacgtttg
    47701 aagaactggg ggtagaccgt ctgtatgtgg atgaagctca ttattacaaa aatgcattcc
    47761 tttacacaaa aatgaggaat gtggcaggca ttgcccagaa tgaagcacag aaatcggcag
    47821 atatgtttaa caaatgccag tatctggatg aaatcaccgg caggaaaggc attacatttg
    47881 caacgggcac gccggtcagc aacagcatga cggaacttta taccatgcag cgttacctgc
    47941 agtatggcaa actgaaccgg atgggactgg gacattttga ttcctgggca tccacctttg
    48001 gtgaggttgt gaccagtatc gaactggctc cggagggtac tggataccgg gcaaaatcca
    48061 gatttgccag gttttacaat atcccggaac ttatgagtat gtttaaggag attgccgata
    48121 ttaagacggc agaccagctg gaacttccgg tgccggaagc ggaatatgaa acggtggttt
    48181 taaaaccatc cgagcaccag aaagagatcg tggaaagcct tggagaacgt gcagaagtaa
    48241 tccgggacgg cggtgtggat tcttctgttg acaatatgct gaaagtgacc aatgatggaa
    48301 ggaagctggc actggatcag cgtcttgtga atccattgct tccggatgat ggggacagta
    48361 aaatctgtgc ctgtgtggag aagagctttg ctatctggaa agagacggca tcaaaacgat
    48421 ctgcccagct cattttttgc gacctcagca caccgaaagg ggatggaaca ttcaatgttt
    48481 atgatgacct gaaaaagaaa ctcatggcaa aaggagtgcc ggaagcagag atcgcattta
    48541 ttcatgatgc caatacggaa gtgaagaaaa cggatctgtt cagtaaagta aaatccggac
    48601 aggttcgttt tttactgggt tctaccgcta aaatgggtgc cggtaccaac gtgcaggacc
    48661 gtctgattgc cctgcatcat ctggacgtag gatggaagcc ttctgatctg gaacaaaggg
    48721 aagggcgtat catccgtcag ggcaatagga acaagaaagt gcatatctat cggtatgtga
    48781 cggaaggaac cttcgacagt tacatgtggc agctgatcga aagcaagcag aaattcattt
    48841 cccagatcat gaccagcaaa tccccggtac gaagctgcga ggatgtagac gatacggcat
    48901 tgtcctatgc ggaagtaaaa gccctggcaa cggggaatcc ggcgattaag gaaaaaatgg
    48961 cactagatgt ggaagtatcg aagctgaaac tgctgaaagc gaattttgtg agcaaccatt
    49021 accggctgga agatgatatc gcaaagaatt tcccacagca gatagcagta cttagggaaa
    49081 gcatcgaggg attcaaagcg gatatggaac agtatcaggc aaataagacc acggatccgg
    49141 agaaatttgt gatggaagtt ggtgggacag tattctatga gaaaaaagaa gcaggagcag
    49201 cccttcttgc tgtctgccag tccatgaaac aggcggatgc catgatcaat gtcggacagt
    49261 atcagggatt ttccatccgc ttaaagtttg attcctggaa taaggaattt atcctttccc
    49321 tgaaaaatga aaacgtatat cgtgtcagcc ttggttccga tgaaaacggt aatatcatca
    49381 ggatcaataa tgcattggag gcaatcccgc aaaaactggc ggaagcagag cgtaagcttg
    49441 agacggtgca gggacagctg aaaaatgcga tggaagaggt gaaaaaacca ttcccgaaag
    49501 aggaagaact gaaccagaaa ctggaacgtc tctcggaact gaatgccttg ctgaacatgg
    49561 atgaaaagga aactgtggtg gagggggaag aagagcaggg cgaggagaaa gaagaacatc
    49621 agtctcttca taacagaatt actgctatca aacagaacag ccagagacag gatgggaaag
    49681 agcctgcaat gagaacatca gaagtgtgta tcggataatc tttcggatat acaacaggag
    49741 aaaaatgttg tagaataggg gcatggggtt atgccccttt aaatgaacaa atcgttgttt
    49801 ggcgatttgg taaatcccga taaatttatt ttatagggaa cagaaacttg attagaaacc
    49861 aatcgaagtt ggtgtaaacg ataaagcagc ttacaatatt tgataaactg ccctatcgtt
    49921 tacatcaatt tcgatttttc tatagtgaac aaagtcgcgt caccggagcc gctatgtatg
    49981 gactttcaat ctttacactt tactataaga taaaggttgt gccattgtgg cagatagctc
    50041 gtttctgaat ctaagcacga caaataaacc tcatttctga ggcttttcaa aaaatatgaa
    50101 tactaagctt taaatacgta gtggtatccg ctgttgtggt tttcgaaggt gtccgccaca
    50161 gcgtttacag acagtaacct ttataccgta gagggtttcg agtatctgtg gagtatccag
    50221 gtctttcagc cgggaaagat actgtttgca gccaaggaga ttccgacata atgtcagatg
    50281 tctggttttg gttctggtgc atagtaatcc ataatgcctg attctgacaa agcgtttcgg
    50341 tggcacatgc ataagaaacc ggcgaataaa ttcaacaccg gaaatggtaa attccttcca
    50401 tttgccttct tctcggtagt ctttgacata gtaagtaact gtatcttcat ccatgcggat
    50461 gatacgatgg ttgctgatgg caatccggtg ggtgtatttc ccaaggtagt taataacgga
    50521 ctgtgcacca ttaaaggttt tcttgcagtg gggaacccaa tccttttcat agcaagtatt
    50581 taggagttcc ttgaaagcat aatggttgcg gtacttttca ctgcttccgt gaaactgaag
    50641 ttttctctct tcccagaggt ttttcagttc atccagatat ttaccccgaa acagttttga
    50701 taacactttt accggaagaa agaattcttc tcctttatca cgccattgat tgttggaagt
    50761 cagaccacca ccgagtagaa tgacatgaat atggggatgg taattcattt cagagcccca
    50821 ggtatgtaac acgcaaatat atccaatctt tgctccgaga tattttgtat cttcggtcag
    50881 ctcatttata gttgcggaaa cagaatgata cattgcatca tatagaagct gctggttgct
    50941 gtagattaaa gaattgagtt cttgtggaac agtaaatacc acatgaaagt aaggagcatc
    51001 cagaacatcc tcacggcgtt tgtcaatcca catttctttt ggcagtgcct gacacatggg
    51061 acagcatctg ttacggcagg aattataatg gatttgcaag tggccacagt cctcacacat
    51121 gcttacgttg gcaccataag caccggtttt gcagttgatg atgcagtttg caactttgaa
    51181 ttgctgggaa gaaggtttgt atttatcaag gtattcagga taaaaccgta gaaatatatc
    51241 ctgtacagta ggatgcttca ttatgaatcc tcctgtatat caaaaggact tttaatgcca
    51301 agtaaagttt tgttactgac atgaagataa atctcggtag acttaggatc caagtgacct
    51361 aacaatgcct gaatatattt aatatcacat ccgtcttcca gaagatgact ggcgaagctg
    51421 tgcctgaatg cgtgggaagt gacatgctta gggattccgg ctcgttcaga gcttcttctt
    51481 aatacttggt ttaccgcaga gatatccaga tattctccgg ttgtctgact tggaaagagg
    51541 atatttctgg gtctttggca ctgaaaccag tactgagtca gaatgtcgag agtgcggtca
    51601 gccagaatgg tgtatcggtc cattctgttt ttggtattgc ggatgtgaat ggaatgattg
    51661 cttcgagata tatcatcata atgcaagtgg gttgcttcag atacccgaag accgcctgag
    51721 tacataacag caaagatggc cttgtacttc aggtttgtgg tgacatcaag aatggcattc
    51781 acttcttccc ttgatagaac cgtaggcagg gaacgatcac gtttcattct gggaatttca
    51841 tcttcgtccc agttgagttt gagtacccgc ttgtacatga agcgtaaagc accatagtaa
    51901 tggttgtagg tttcaggtaa aatgcccatc cgtcttttgg tggtcaggta atcatccgca
    51961 tcagctacag taagttcctg ccagggttta ccggtagcat tcaggaaagg gctaagggcg
    52021 tgacaatacg cctttgtagt ggattcctta agattctttt tctgtgcagc aatagttact
    52081 aattcaaaaa tatcttcgta cataaaataa cctccatgaa ataaaagtag taataacaac
    52141 agtaactacc catcatggag gagcatttgc aaaataaaac tgcttgtgaa agcagcctga
    52201 aggtggtatc attttcatag gcagttgttg ggactaagcc cgtgtttgaa gtttgttatt
    52261 ggtggtgctt taacaatact attttgggac gatcctgtca ctgccttttt tggaaaaagt
    52321 aaaaagctgc gccacagcct tggcaggcca tcgcgcagcg attttgttca ctttgaattt
    52381 tacggtcagt aaggaatgag taaagttata tgattgtatt ataagcgatt tgttaaattc
    52441 ttgtaaccac ttgtatttgc ctgcgattta tggtataatg ttttgaaatt tagaaagagg
    52501 tggaaagatg attaactttt cttgcaaata aaatcaaaat atgcggtagt gctatacttt
    52561 ggcattattg tgtctattgc aagaaagtta tatgtctatc ttactcaata tagtgctgtt
    52621 gccacttttg cttagtggtg ttattatgct atgacgagct gcaaggataa actttcttgc
    52681 ggctcttatt ttgttttgga ggtgctttat gaatagtgca gaacagatag ttacacatga
    52741 ttcactccgt atagtgtcgg ttccttttgg tgaaatctat acggagtaaa cattcaccga
    52801 accgactttg tatcgtatga cacgcaaagg aggataatat ttatgtcaat gattaaaatt
    52861 gaaaacctta cgttttcata tccgacaagt tatgataatg tttttgaaaa tgtcagtttc
    52921 caggttgata ccgattggaa gcttggtttt gtgggcagaa acggacgagg taaaacaacc
    52981 tttctgaatc ttctgcttgg gaaatatgag tatagcggaa aaatcctatc atccgtacag
    53041 tttgattatt ttccttatcc cgtttcagat aagaatcgta ttacagagga tatattgcag
    53101 gaggtttgcc cacttgcgga agaatgggaa cttatgcgag aactttctta tcttgatgtt
    53161 gatgtcgatg tgctttggcg accttttgaa acactttcca acggagagca gacaaaggtt
    53221 ttgcttgccg ctctttttct taatgaaggg catttcctac tgattgatga acctaccaac
    53281 catttggatg ccaaagcgag aaaaagtgtg gcgacatatc tgaaaaagaa aaagggattc
    53341 atcttagttt ctcacgatcg tcgctttctt gacgattgtg ttgaccatat tctatcgatt
    53401 aaccgagcga atatcgaagt gcaaagagga aacttttcat catggatgtc aaattttgag
    53461 caacagcaag aatttgaact ggctcagaac gaacgtttgc aaaaggacat cagacgatta
    53521 cagcagtcgg caaaacgctc tgcagtatgg tctgaacgtg tagaagcttc caaaattggg
    53581 gcagcagata aaggttatgt cggtcataaa gccgccaaaa tgatgaagcg ttcaaaatct
    53641 atagaagcga gacaacaaca gacaatcgaa caaaaatcag cattgctgaa aaatgtggaa
    53701 accgcagaag cactcaagat acaaccgctt aattaccata cagatttgat tgcatcatta
    53761 tcgaatgtag tagtttgtta tgatggcatt tcagtttgtg aacccgtttc gtttgaaata
    53821 agacagggag aacgcattgt gcttgacggg aagaacggca gtggcaaaag tagcctatta
    53881 aagttggtag tcgggcagtc catagattat acgggtacag taacacttgg ctctgggctt
    53941 gtaatttctt atgtgccaca ggatacatcg tatttatgtg gaaccctttc cgagtttgca
    54001 gaagaaaaca accttgatga aagtctgttc aaggcaattc ttaggaaaat ggactttgag
    54061 cgtatacagt ttgaaaagga tattaaagac ttttctggcg ggcaaaagaa gaaagtccta
    54121 attgcgaaaa gcctttgtga aaaggcacac ttgtatgtat gggatgaacc gctcaacttt
    54181 attgatgtgt actcacgtat gcagattgaa cagctcataa cggagtttgc cccgaccatg
    54241 ctcctggtag aacatgataa tgtttttcga gatactgtgg caagtaatat tgtgaatatc
    54301 taaattaaaa taattgtatg ggttaattcc agttttacag agactcaaat ttcagttttt
    54361 agagctgaat caacatttaa tgacgatgga actaaaagta aaaaaattca attatgtttt
    54421 ataaccgata tacaccggca gtgaaatacc tgccggtttt ttcatgcccg gaaggaggtg
    54481 ctatgtgaag agaacagaga aagtattgtt gattgtgttt ctggttgtta cgttgatatg
    54541 tgggaaatac ctcttggatt actggcagga ttcttatgac aacaggcaga attaccgtca
    54601 ggtggaggag atagcattcc cggaaaagga tacagaggaa gacgggactg gttccaatgc
    54661 ggataatcca atgacagaga tagatgattt tgattatcag gctttgctgg atgaaaatgc
    54721 agactgcatc gggtggctga agattgatgg aaccgatatc agttatccgg tcgtgcaggg
    54781 agaagacaat gagttttatc ttcgccatga ttttcaaaag aattatgcca tctgtggaac
    54841 cttaatgctg gactgccgga atgatataga tgccgggcag gaacatttga ttatttatgg
    54901 tcaccaaatg aaagatggca gtatgttcaa gcaattgaat ggatataaaa aagaagagtt
    54961 ttatcatgag cataaggaga tcacactata tctggaaaac cagaaatacc agtatgaagt
    55021 ggctgctgtg tatgtgacta atgtggcaca aagcggtggt tattatgatt ttttacacaa
    55081 agaaacacga aaacaacaga tggattattt acagaaaatg gcagcttatc agctttatcc
    55141 gctgggggtt accgtcaggg aggatgatga gctgctttct ttatctacct gtgaatattc
    55201 cagcaccaac ggcaggctga ttgtacttgc cagaagaatt ggagcatagg gaggaaaggc
    55261 atatggcaat gaacaggaat atgacaatgg cagaaaaaga agttcgggat tatgcccaga
    55321 aacagatgga acgggcagaa cagtgggaaa acattttatt tacagaggaa cagaaagaac
    55381 aggttctgga atatgcggct atgactgggg atgattatga tatcaggaaa atgatcagag
    55441 accttgcaga tgctgttcgt tcctcggatg aagagaaggt ggatgaaatt ctgagggatg
    55501 caagagagga aattgacgaa ttcccggatc gttccgttgg tatggcagaa ctaaagggat
    55561 atggttatac cgcagatgat atgtttcccc ttcgtcagga gatggcactg gagcttcatc
    55621 gtgtcgggga aaaggtgtac tgcctgcagt cagaaggcac tcatggggac tatgccagca
    55681 gggagatgat attggaacat gaaggtctct atggaattga aaaagaggca tggcagcgta
    55741 tgcaggagca ggaggacgaa atagattttg aggaagctgg attatatcag cccccaatga
    55801 tagatctgga tagaaacgaa gcattaagga tgttcgatgc aggggagacc gtatatttga
    55861 ttaccactta tccaaggccg attgcagtgc ggaaacggat ggagattgaa agaggaccgg
    55921 agcgttatca gatggagaga gaagatgtgg aacggatcag gacgttggag aaacggatgc
    55981 aggagtatcc gcagataacg tcactaaaag aggcgaaact tcttctgggg acagaaaaca
    56041 gatatggaat ataccagatc atagacggca gtcccggcag aaaatatgaa tttatggatc
    56101 tgaatttcat tgaaagacat ggatatcagg taaaaaaaga ggactatgag ttaatctact
    56161 ccgatgaaat gcattatggc gatacattgg attccctgta tgaaaagttc aatattgccc
    56221 atccggaaga ttataccggg cattctttat cggtcagtga tattgttgtc ctcaatgaaa
    56281 atgggaatgt aaaagcctat tttgtagaca gtatcagttt ccgtgaattg ccggatttct
    56341 tgcaattgga gccggaactg aaccaggagg aagtggctta ccggatcggg gatcaatact
    56401 ttgctattca agtggcaacg gagggatatg attattcctt ttatgataag gagtataagc
    56461 tcatggacgg aggcattttg gagaatccgg atatttctat gagacaggct attcaggata
    56521 ttttagagga cgagggactg gaacagttag aacggatacc tgtagattat gatgaattgc
    56581 aggaaaaagc ggaagaagtg gaggcagaga ttcttcagga agtaagaagc cagagaaagc
    56641 gtgtgccggt tatttcagat tatatcaaag cggaagctgg attaaatgga atgagccggt
    56701 cagaaatcga agagaccata tgggcgattg cacaggcaga gattattgaa aatgacctgg
    56761 atgccaggat acaggctgtg cgtgtgtacg gaagccgtac aagggatggg ctatataaac
    56821 aggattctga tgtggatgtg gtaattgctt atgagggaac tgtacgtgag gatgatttgt
    56881 tttctgcatt gaatgaagca gggtataagg tcggaaatat gagagtagat atgaacccga
    56941 tcagaccgga taagactggt acgttagaag attttcttga aaaatccgaa cggtatctgg
    57001 atgaaaaaac ggagcagatg aaagccagag gggagtacaa gccattggcg aaagtagaag
    57061 agttggaaga ggcaaactac aatatgatcg ataacgtcct gaacaatatg cctccgaaga
    57121 aagagccgta tctggaatac tatgctgcgg aatgtgatga ataccatagt cttggcaaaa
    57181 tatataagag tacaaatctg gatgagatat ttgcaaaata ccgggaaatc attgatgacc
    57241 caacgttaag ctactatgga aatggcatgg gcattattta ccgtgacccg aatgatactt
    57301 tttatgatga agctgaggta tctttggtca gccggaaatc gatccgggga gacagtctgg
    57361 atgatgtggc attcctggca gcccttccaa tggtacatga agcactggaa aagattgtag
    57421 aagcatttcc ggattttcgg tattatcctc caaaggaatt ggatgttcat tattatccgg
    57481 agaaaatgaa tgcggatgaa ctggctgcag cactggatca attagcggaa gactttgacc
    57541 attatgatta tcatgataac tttagcccgg aggaagatat ggtggaaact gtcgcattag
    57601 aattaagatg cggctatgcc cataggtaca ttccgttttt gaaagatatt atagatgagg
    57661 aatgcgaaga gtctccccgg gcagaagaac ttctggagaa actgaaagcc tatcagcctg
    57721 agataccgga aacagcagta ccggttgtcc gcatcaattt ctgtgaggat aaggaaatgg
    57781 atatttcggg ttatcagaag ctgggaagtc tggatgaaat aacagccaaa atggatgcag
    57841 aactggcttc acaagcagat tcaaagactg gaatgccgga gaaaactgta cagatgtact
    57901 ttacaattta ctacccagat catgaccaga tgcaggaact aaaagggaaa atcaatatcg
    57961 gagatggaaa cggcggtatt gtgagccagt tgaagaacca gaatgaaatg aagatgcatg
    58021 atgagagctg gctgaattac caaaaaggta agggtgaaga atcctttcag gcatatatag
    58081 ctgatcttac agatatgcag gagcatgtgc tgccgtattt gcagagtttc tgcagtttgg
    58141 aagaaagagc accagagaga tcagtagaat cgaccacggt atcaaaatct gaaatggaag
    58201 cagggaagac aataacatct ggtaagaatg aaaaggcgaa accggtggag ccggtgaaaa
    58261 agtctattca tgagcgattg aaaatcaata aggagattat tgctaaacaa cagggaaaag
    58321 atgaaccgga gagaggagtt ggtaaagatc tgagaacagt gtaacagggg gctggaagta
    58381 ctataattat atagctactt ccggcttttt tgcatataga attggaaatg tgtgcttgaa
    58441 taacatgtac aataaaattc ccaggtgtga tatactattg ctatatgcga aggagaggta
    58501 tgctatgccc aaaggatcaa atcaaaaatt taaattatat cggctggcag aaataatgct
    58561 ggaaaagact gatgatgaac actatataac tatgtcagaa ataaaagaat cgcttgagga
    58621 atatggaata acagctgaca gaaaaagctt gtatgcggac ttgaaagatt tagaaattct
    58681 tggcattgaa gttgaaggtg aacctgttaa aaataaatat cattaccatg tcataaaccg
    58741 gccttttgaa ctcccagaat taaaattact ggttgatgca attcagtcat caaaattcat
    58801 tacggagaaa aaatcaaata cgctgattcg taaattggaa aaactggtaa gtaaatatga
    58861 tgctcaaaaa ttgcagagac aggtgtatgt ttccggaaga ataaaaacaa tgaatgagag
    58921 tatttattat tcagtagatg caattcataa tgctattaca gagaacaaaa agattaaatt
    58981 tcagtatttc caatggaatg taaaaaaaga aatggaattg cggcatggtg gcgcatatta
    59041 ctatattagc ccttggggat tatcctggga tgatgaaaac tattatttga taggatatga
    59101 ttctgaggca agtatgatta agcattttcg tgtggacaag atgctacata ttgctttgtt
    59161 agatgaaaat agagaaggaa aagagcattt aaaaaaaatg gatatggctg attatgcgaa
    59221 aaagagcttt ggaatgttcg gtgggaaaga acagacagtt aaattactgg ttgataatac
    59281 attgtcgggg gttattatag acagatttgg taaaaatgta attttttatt gatttgatag
    59341 acggaaatct tcttataagc ccgcgcaagt gtttataaaa cctcgcgaaa atggcttaaa
    59401 atcaaggttt tctgcatatc gtcatttatc ttgccatatc tccgtataag atgattttgt
    59461 aagaccgggc accattttgg caccacaaat tataggagga cgacatgaaa aacgtacttt
    59521 tagacaaggg tattatactc ccgtccggcg aaatcagcaa ggataaggta aaccttgtaa
    59581 ccggagcaat cacgcagcca ttcgcagaaa tggtatgggt aacgacaggc ggcgacatgg
    59641 aaaccgtaaa ccgcttgacc gacgtacttg ttaccatgaa cacccccgcc gaccggggga
    59701 agctgttcaa aatcataaaa atgctctatg ggcttatggg cttgcccttt tccgaggaag
    59761 ccgagcctat ggacgcagac cccgccgttt tggaatactt cattttttcc tttacggcag
    59821 actttggcga agtcatacaa gacctcatag ccgaagaagc agaataacgc accgcacagg
    59881 cggcgtttct cacttcccac aaggaagaac aggaacgccg cttttttcat gccctttgtt
    59941 acgcagtagg catgaaaaag cccttgattt acgcggcttt gcggacgcgg ttttcagcgg
    60001 ataagggatt gatacctaaa ccctcaaaat cgcgtttcta ttgcgtaaca ggtatgcagc
    60061 aaaggagtga tgaagctatg gcagttttca gagtggagcg caacaagggc tatacggtta
    60121 tgagcaacca ccacttacgc aataaggagc tatccctaaa ggcaaaaggg ctgttatcgc
    60181 aaatgctgtc cttgccagag gattgggact acacccttgc ggggctgtcc tttatcaacc
    60241 gggagaaaat cgacgctatc cgggaagccg ttaaggaact ggaacgcgcc gggtatatcg
    60301 tgcgttcaag ggaacgcgac gagaaaggac gcttgcgcgg cgcagattat gtgatttttg
    60361 agcagccgca gaccccgcct gtatcggatt tacctacatt ggaaaatcca acattggata
    60421 atccaacgtt ggaaaaacct acgcagaaaa aacctacgtt ggaaaatcca acgcaattaa
    60481 ataaagatat acaaaagact aacttaccca aaaaagaaaa atcaaatata gatttatcaa
    60541 gtaccgattc cattcctatc cattccctaa atcccttgcc ttacgacggg gaagcggcag
    60601 agccgccgga acggaaacga aaggaagcga cagacgcata cagcgtttat gaggaaatca
    60661 tcaaggacaa tatcgagtac gaccattttg tacgctacgg gcaggtagac aaagaccgtc
    60721 tggacgaaat tgtttcgatt atccttgaaa cggtatgcag caagagaaag acaatccgta
    60781 tcgccgggga cgattacccg gcagagcttg tcaaggcaaa gtttatgaag ctcaacagca
    60841 gtcacattga atttgtcttt gactgcatga aagagaatac caccaaaatc cgcaacatca
    60901 aacagtacct taaagcggtg ctgttcaatg cgccgaatac cattgacagc tactataccg
    60961 cccttgtcgc tcacgacatg gcgacaggca aaatctaaag gaggattacc acatggcaca
    61021 gaaaacagga gctttgattt ttgacgaaca gaccgaccgc tacgacattc gctttgacat
    61081 tgccgactat tacggcggct tgcattgcgg agagtgtttc gacgtattca caggcggcaa
    61141 atggaagccg acccgcattg aaatgagcgc ggcgcaggaa tggtaccttg tgggtatccg
    61201 cgccgaggat ttgaacggct tgcgcgtccg tatctaaagc ttatgggcgg ctaccgcagc
    61261 ggcgtaccac cctaacacta tcagactacc gcgaaaggag gacggtaaat gcaagatgaa
    61321 atcaacgaaa agaccatagc cctttagtgt gttatacgct ctgtcggcgt tgccgtgaaa
    61381 atgc
//
LOCUS       DAMKOJ010000244        45173 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.028, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000244 DAMKOJ010000000
VERSION     DAMKOJ010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.028"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            285..623
                     /locus_tag="PC592_003718"
     CDS             285..623
                     /locus_tag="PC592_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057604.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            645..962
                     /locus_tag="PC592_003719"
     CDS             645..962
                     /locus_tag="PC592_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057605.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVSILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLILQIIDIIKK
                     NKI"
     gene            1112..1792
                     /locus_tag="PC592_003720"
                     /pseudo
     CDS             1112..1792
                     /locus_tag="PC592_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905814.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2133..2900)
                     /locus_tag="PC592_003721"
     CDS             complement(2133..2900)
                     /locus_tag="PC592_003721"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF4057606.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKEDIIKEAKELKGVCLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYISDIPLLFTFRSLAEGGEKVISKDYYTTLN
                     KEISSTGLVDLIDVELFMGDEVIDEVINFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQDEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELSSVLNLLHKSIN"
     gene            3661..4293
                     /locus_tag="PC592_003722"
     CDS             3661..4293
                     /locus_tag="PC592_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF4057607.1"
                     /translation="MTIPNSTKVYPRNNDYQTVYLKNVITRENIEVGDYTIYNDFCND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHTLKSKSTYTFPIFYEEW
                     GLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVHIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNNTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDELV"
     gene            complement(4666..5535)
                     /locus_tag="PC592_003723"
     CDS             complement(4666..5535)
                     /locus_tag="PC592_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF4057608.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELIELRKLGVKMIYLGLESGSNEVLEDIKKGFNSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGKISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(5631..6488)
                     /locus_tag="PC592_003724"
     CDS             complement(5631..6488)
                     /locus_tag="PC592_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF4057609.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKKNNRKFN
                     IKNKIFKGIGILFVLILLSFFIWINKTYEPQKLAKEALISNSKVEVTVKENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVVASNFARDNKLIDGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNLS"
     gene            complement(6703..8721)
                     /locus_tag="PC592_003725"
     CDS             complement(6703..8721)
                     /locus_tag="PC592_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF4057610.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYIFSYDLK
                     RAVYVPFGLMYIFMVSIPVGISEFPMRLSALAAGAVIIMIAQFVMNRNRMKNIGDKEL
                     ISICDELLEKISLLKNIINDDSSISKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERINLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEVNYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKI
                     KSRDEKKAERKSNIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIDMYKGIVKNIIDEVNKSIENVADVYYIKNLLLVPSLIEDRIMLINAI
                     YKDKYQEDFLENQKLLISNMYNLYINVNKNKIQDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKTLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEVA"
     gene            complement(8993..9769)
                     /locus_tag="PC592_003726"
     CDS             complement(8993..9769)
                     /locus_tag="PC592_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF4057611.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALILGLIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     VLCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSIANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(9826..10797)
                     /gene="asrC"
                     /locus_tag="PC592_003727"
     CDS             complement(9826..10797)
                     /gene="asrC"
                     /locus_tag="PC592_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF4057612.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLTIVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTKFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDGDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDENSIIKIILNTYKYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGVKYL"
     gene            complement(10810..11601)
                     /gene="asrB"
                     /locus_tag="PC592_003728"
     CDS             complement(10810..11601)
                     /gene="asrB"
                     /locus_tag="PC592_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF4057613.1"
                     /translation="MNPYIPVNAKILDIVKHTDKEWTFRVNCDTKGVLPGKFYEISIP
                     KYGESPISVSGYGENYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIAGFKSPKDVLFADDLKRWSKKLDI
                     LVTVDGADEGYSGNIGLVTKYIPELDIKNINNTSIVVVGPPMMMKFTVGEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDNTYICLDGPVFDYSYAKNLID"
     gene            complement(11602..12609)
                     /gene="asrA"
                     /locus_tag="PC592_003729"
     CDS             complement(11602..12609)
                     /gene="asrA"
                     /locus_tag="PC592_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF4057614.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVSIPFKGTFSDTDVIRYK
                     EVNSFEEMEFTKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIREKVKFVLVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEIFNGETTEFNIDYVTDNLISVDVPENIDSNEMIRNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVTSKEE
                     I"
     gene            complement(13000..13689)
                     /locus_tag="PC592_003730"
     CDS             complement(13000..13689)
                     /locus_tag="PC592_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF4057615.1"
                     /translation="MSKLKDYNIDKVMIFNKLSTKTKNQLKEKAKLKRLQKKEILFYE
                     KDSLDSVYMLLEGKVSIFKISENGERKVIFILNSGEVINDITFDSSKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQSDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(13752..14600)
                     /locus_tag="PC592_003731"
     CDS             complement(13752..14600)
                     /locus_tag="PC592_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF4057616.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(14619..15506)
                     /locus_tag="PC592_003732"
     CDS             complement(14619..15506)
                     /locus_tag="PC592_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF4057617.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGLIIDKSSLDTEAKEKGGEGIL
                     SKIKGIVKKYIKENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEIEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNINGSSFQELASTSSLIKKVAKIKNLNENELNGKIIFDLAKNNDEGCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(15564..16367)
                     /locus_tag="PC592_003733"
     CDS             complement(15564..16367)
                     /locus_tag="PC592_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057618.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESVIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NAGCATLSKHYNIENKYVIWIQGESDAKYGSDALYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACNECDILCVGSKIAMQFHDKGLTIDDVHYTQE
                     GLNILGKDLCKNIYKYHTTKEKELLSDTIDLSEARRYIYELEKISKKFV"
     gene            complement(16527..16979)
                     /locus_tag="PC592_003734"
     CDS             complement(16527..16979)
                     /locus_tag="PC592_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF4057619.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEEGDFL
                     PLDGKNNGYVELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(17109..18611)
                     /locus_tag="PC592_003735"
     CDS             complement(17109..18611)
                     /locus_tag="PC592_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF4057620.1"
                     /translation="MVGFTWIDFTILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIVVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YCMPEVTSWAYSLITITTSVVVGTIFSAIEAKVKAKVSLPRAETTVYYEK"
     gene            complement(18644..19510)
                     /locus_tag="PC592_003736"
     CDS             complement(18644..19510)
                     /locus_tag="PC592_003736"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF4057621.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            complement(19595..20266)
                     /locus_tag="PC592_003737"
     CDS             complement(19595..20266)
                     /locus_tag="PC592_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF4057622.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCISTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKRVFELGVYSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(20542..21033)
                     /locus_tag="PC592_003738"
     CDS             complement(20542..21033)
                     /locus_tag="PC592_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF4057623.1"
                     /translation="MEGNINNKVDDKFSKVKKKFGNGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSIDDNSFDKFCDELLELDKLIYEKNMEINEMEMVESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIVCGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            complement(21055..22419)
                     /locus_tag="PC592_003739"
     CDS             complement(21055..22419)
                     /locus_tag="PC592_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF4057624.1"
                     /translation="MGEKKINNMNYSHNNYSKTTGEPTRKIKNSHITLKNKEEKICSS
                     CNKENNTKDNYCKFCGNELYEITSLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKSVLANSIGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIKTFIL
                     GYVLVLIILFVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIKPIVVFSIYY
                     AFLMGMLALFSTFILDSNINFFNTTSYGATLIMQFKVLQAIVISFIYSFVISLIGYKL
                     NSAD"
     gene            22838..24013
                     /locus_tag="PC592_003740"
     CDS             22838..24013
                     /locus_tag="PC592_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF4057625.1"
                     /translation="MNLEKIKKFWGFPLDKKHKENVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFATPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKLGESVIVFGGCFLF
                     LNFFLPGIQTIPGNEFSNIVNTFFITSLAVFVSTMLYRSRVFTYYDKLLISQQYEEIY
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCDEEDAKLKSECLRKII
                     ETCNFERDDIPLKCVTVSIGVYTNKIERTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(24186..25583)
                     /gene="asnS"
                     /locus_tag="PC592_003741"
     CDS             complement(24186..25583)
                     /gene="asnS"
                     /locus_tag="PC592_003741"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF4057626.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFVRITYTKAVELLIESGHDFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(25660..25893)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(26051..26245)
                     /locus_tag="PC592_003742"
     CDS             complement(26051..26245)
                     /locus_tag="PC592_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF4057627.1"
                     /translation="MENKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVTEAKDWVDNGSKL"
     gene            complement(26497..28170)
                     /locus_tag="PC592_003743"
     CDS             complement(26497..28170)
                     /locus_tag="PC592_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF4057628.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPIDFDET
                     ILNNIIQVAWWEESAPMSSLIEITNNVDNGETITTAAGTEYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILAGNGRVNSKYRGITTESDLIVVKLKSYIGTYYAGRINYSV
                     SDFLAAITYVTNIARTENRPLIINLTIGVKSGAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYAPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWTLRLTSELI
                     IGGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVAPGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQNNI
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            complement(28180..31578)
                     /locus_tag="PC592_003744"
     CDS             complement(28180..31578)
                     /locus_tag="PC592_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF4057629.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNTLLTYPEIEFIEKPFVLQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSNGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELKMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLRNNITEEVEF
                     IVGEGERILNVNIWPDFVDDFSVHLVNPSNNQTQTISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWRIIFEPINIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKVARRLSNQSY
                     PNNSSGFGFLNLSDVDLYTLSSINQDLETEDIGYRSINKSFMDEANNYIPIDGYNVQI
                     HNGLEKEKYISKNISRQSGILSGIDVVHTPEFEEELAGLGQSQNFLKISDSLGVLSID
                     NTDYNSIQQVLQLPSIIRTIPTTKMTLLGEINRGTFGGVVATEEIGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHRDFIYPDGTSKIVYLWDQTKEGNPPDGFYIGTEYTREDIN
                     RAIAANDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGVAEDSELIVIKLGKIEGFYNS
                     AMLFAASQYAYNKAFELGRPLVINVSLGTSSLAGLTNRVNSEKAFFTRGLCVTAGAGN
                     EGNTQTHTSGIISHVGGSVEVELELNEEEEELSLELWLSRPDKADVIIVSPTGEESKT
                     VGVSNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRKLLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINSSLWQSSSRG
                     PTIENRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            complement(31744..32940)
                     /locus_tag="PC592_003745"
     CDS             complement(31744..32940)
                     /locus_tag="PC592_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF4057630.1"
                     /translation="MFIEFFYLLRSRGVNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDTVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWVLKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFRRKYSKTVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            complement(32961..33782)
                     /locus_tag="PC592_003746"
     CDS             complement(32961..33782)
                     /locus_tag="PC592_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF4057631.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKNLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGIPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            34242..35336
                     /locus_tag="PC592_003747"
     CDS             34242..35336
                     /locus_tag="PC592_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF4057632.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTIMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTTALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            35487..35843
                     /locus_tag="PC592_003748"
     CDS             35487..35843
                     /locus_tag="PC592_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057633.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(35936..37204)
                     /gene="eam"
                     /locus_tag="PC592_003749"
     CDS             complement(35936..37204)
                     /gene="eam"
                     /locus_tag="PC592_003749"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF4057634.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEHIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTYIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPIYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(37605..38666)
                     /locus_tag="PC592_003750"
                     /pseudo
     CDS             complement(37605..38666)
                     /locus_tag="PC592_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
     gene            38668..39018
                     /locus_tag="PC592_003751"
                     /pseudo
     CDS             38668..39018
                     /locus_tag="PC592_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
     gene            complement(39165..40700)
                     /locus_tag="PC592_003752"
     CDS             complement(39165..40700)
                     /locus_tag="PC592_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057635.1"
                     /translation="MRFIKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKDPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNRVSAVGVGKATIYAKCGNKEVERTFRIEARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPIERAISLSSNGNIVGL
                     REGKDRVRITCGDKSKIITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNVDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMKVESISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNNSQNSDVI
                     NVR"
     gene            40975..42024
                     /locus_tag="PC592_003753"
     CDS             40975..42024
                     /locus_tag="PC592_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF4057636.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEIGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MIGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSVGKGGTSMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            complement(42073..43107)
                     /locus_tag="PC592_003754"
     CDS             complement(42073..43107)
                     /locus_tag="PC592_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057637.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKEINSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLNESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARGKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(43125..43472)
                     /locus_tag="PC592_003755"
     CDS             complement(43125..43472)
                     /locus_tag="PC592_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF4057638.1"
                     /translation="MIRKKSELQVEVKENLNGGIGNVKLENIIQNEELKGKGRLFKRV
                     SLPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            43730..45112
                     /locus_tag="PC592_003756"
     CDS             43730..45112
                     /locus_tag="PC592_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF4057639.1"
                     /translation="MSVLKTQEKLKQPKDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLSWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGASISMYGYRYVFLFSSITVLIGLFFFVFGNRKFYNSLN
                     NNHSNERESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVMQTGTDSNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISLLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSS"
BASE COUNT        15011 a         7481 c         4924 g        17757 t
ORIGIN      
        1 atattctaca tatctaatat gtaattccaa taaaaaatgc tataattaac atattatcaa
       61 ttcgttttat tattgtagta cggctatgaa attataaaaa tatttgtcta attaaaaata
      121 tgatttatcc atatttgttt attgtagata cagactatac aaaaataaat agcacttatt
      181 tcagtataaa aacatatata gtctatattt aaactaaaaa agtataaata gtctatataa
      241 aacaacttaa actatgaata taatctaagg tggagggata ataattggca aatataggaa
      301 aaataatagg agatagaata aaagtctata gaacaaaatt gggatatagt caagagtttc
      361 tagcagaaaa ggcaggttta catccaacat atattggtca gattgaaaga gctgagacaa
      421 atacatctat caatattata atgaaaattg ctactgcttt agacatacca cttgaattgt
      481 tatttgcaaa tattattaca acagaaggcg ttgataactc tgtaccttta gaatgttatg
      541 aaatgattaa taaactaact gaaaaagaac aaattgcaat gctagagtta ataaagtgca
      601 tcattaaata caaagaaata taagcgaggg aaatagtaac aataatgaat tatataggta
      661 aaagacttaa agaagaacgg aaaaaagcaa atttaacttc aaaagaattt gcaaatatgg
      721 ttggagtatc gccttggtat ataactcaaa tcgaaagtgg taaaaagaat ccaagtctta
      781 aaacattcat aaaatttgta agtatattaa atatctctgc agatgttctt ataaaagata
      841 ttacttccac tggaaagaca tatttagaaa atgatataaa tgaagagtta aaagacttaa
      901 attcaagaga actaaatctg atattacaga ttatagacat cataaaaaag aataaaatat
      961 aattctttat attttatata aaaaaaaagg ttatttgaaa taaataacct ttttttgtct
     1021 ttttgtgtta acattgtctt atagtgctaa tgagtactat tagaccatgt tctatggcct
     1081 tattttaata taaaacgatt ggagataggc tatgattgtg attgaaggta gcgataaatt
     1141 taaaattgca aaagaatata ttgatgtaga atatactctt tttagcaaag taacttttaa
     1201 gtatgaaaag ttaaaattta aagataatgc tgaattagaa aaaattaaaa tgtttaaata
     1261 taaaaatggc tacatcccta ataaattaaa cctttcttta ggatatggat tctcttctta
     1321 taaaaaacaa ataattagag aaactgtaga tactttaaga ttgacagaaa ttttttcaag
     1381 cgagaacata gaagatatta aatttataaa agatggtaca aaaaaattag aaattagcat
     1441 agagaaagtt gtgaaattta aacgttgaaa aaaaagaaat tatgtttgtt gctattgccc
     1501 tgatatgtat agagacataa aactcgacaa agaatctatc gataaaatat acaacagaag
     1561 aaaaataaaa atagaaagag aagttaatat ttttgaagat gaggatgtta taataaacaa
     1621 aaaagtattg aaatttccaa aatcttggac aaagaatatg caaaaatatt ggctaagtga
     1681 aaataagtat cccatacatt ctactgtaat tgatgatgat agatataaat gttgtaatgt
     1741 acaatataca aagaatagag tgataatatt atattacata tataaccttt aatatacata
     1801 attacaaaaa agtaattaca aatacacata atacaaatat atcttctact ttagataaaa
     1861 cagttattat aaaaacttac tatctataaa taatagaaat gctagtatac catctataat
     1921 ccaatgtcta gtaggtttta atggcatatt ttaaatatgc catagttgat ttataagatt
     1981 tttataccac tttcaaaata cacactaaat agttgctttt cagatattac acttaattaa
     2041 ccaatttaaa ttttactatc tgaaaagttt tttatattta atttatatat cttcaaaaat
     2101 aactcctaat atttctatat aattatatta aattaattaa tactcttatg taataaatta
     2161 agtactgagc ttaactcttt aaatgatatt tgacctggtg ctgaaacact ttttgcagct
     2221 ccaaaagtta atgcagaacc aaatatttcc ccacacaatc tgcttataac tcccattccc
     2281 gacattgaca ttgttattat tggtctatct gcataaattt taaacatttc atttgtagct
     2341 tcaagtagaa ctaacacatc tttttcatct tgtggcataa cagctatttt gggtaaatct
     2401 gcgcctaatt cctgcattct acataaacga gatacaattt cttctttttt tggagtttta
     2461 ttaaagtcat gattagatat aattactttc acttcttttt tatgagcaaa attaattact
     2521 tcatctataa cctcatctcc cataaataac tctacatcta ttaaatctac taaacctgta
     2581 ctagaaattt ctttatttaa agtagtataa taatcttttg atattacttt ttctccccct
     2641 tctgctaaac ttctaaatgt gaataataaa gggatatcag atatataact tcttaattca
     2701 tagagaactt ccttaacttc tttaatattt tctacattct caaaaaaatc aactcgccac
     2761 tctataatat ccaaacatac tccttttaat tctttagcct cttttataat atcttcttta
     2821 tttttaccga taatcggtac acaaatttta ggtctacctt ctccaatagt aatatttttt
     2881 acttgaactt ttcttttcat attctcctcc ataatcagaa attctatatg attttaaatt
     2941 ctattttctg cataatttaa ttatacatta taaatgctac acattataaa aatactaatt
     3001 taaaaataat ttttattcta attcttaaaa caatcccaca tattttagaa aagatactct
     3061 ataatataaa aacacttctt tcttatctaa atttatttta acattctata attttcataa
     3121 cattacttaa gttttatcta tataatcaat attattctgg atgataatag aattaatata
     3181 taaattatag tataattata tagaaataac tcgaatttta ctacttatga agaaatttga
     3241 tatcaataaa ttcaaatcat ttgcattact tcagagtttt ggctaaagtt aaacaccata
     3301 ctaaacccaa aatagatttt acagctatac ttcaagagta attgattgta atagtaccat
     3361 ataatcatcc tttagcatta agtgacagtg tagattaaaa ggataacaat gttaatgttc
     3421 tttaaattaa aaattatttt gtatataaaa tatattaaat tattgcaagc tttattgttt
     3481 tgatatacaa tcaactaagc atatagcctt tataaaatac taaatagtta aaagtctgtt
     3541 tttaaaaaca aaatgtataa attaaaatat agatactatc aaggagtgat tctgtgaaga
     3601 gatgtattgt aatagtggaa tagtcaaaaa cataatatat atcaaaggag agatttaaat
     3661 atgactattc caaattcaac taaggtatat ccaagaaata atgattatca aactgtatat
     3721 cttaaaaatg taataacaag agaaaatata gaagttggag attacacaat atataatgac
     3781 ttttgtaatg acccaagaga ttttgagaaa aacaacgtat tatatcatta ccctattaac
     3841 aatgataaat taataattgg taagttttgc tcaatagcat gcaatgcaaa atttctaatg
     3901 actagtggaa atcacacact gaaatcaaaa tccacatata cctttcctat cttttatgaa
     3961 gaatggggac tcgatatcaa tcatataacg gatgcttggg acaataaagg taatattata
     4021 attggaaatg atgtgtggat aggctatgat tctataatta tgtcaggtgt acatattggc
     4081 gatggtgcaa ttattggaac aagagcagtt gttactaatg atgtcccacc atattctatt
     4141 gttggaggag tacctgcaaa gattataaaa aaaagattta ataataatac aatttcaaaa
     4201 ttattggaaa ttaaatggtg ggattggcca tataaaaaaa tccaatcaaa cattaagcat
     4261 attcaatcag gaaatataga tgaattagtt taatctttta taatttatat atattaaatt
     4321 ttactttaat aatccttttt ataagaattt tttcaagatt tgtatatcat tttaatatat
     4381 ataaatttaa tacaatacta aacaaaaata aaaagtaaag ttgcttaata taaagttact
     4441 ttacttttta ttatttaaat tcatgggtcc attataatat gtaaaattct attaaaccag
     4501 ttcacatttt catcattatt gatagcctat atatgaacat accattttgt tttttaacaa
     4561 aaaaatcatg ctatattaat agtaaaaaac tattaatata gcatgatttt ttgtatctaa
     4621 acaatctcag tatttatcta taaatataga ttgatatatc aaaaactaca gtcttctata
     4681 ttcttctctt tttaactttt ggttacttag atagtaatca atttcatcaa ttagacgttg
     4741 tttgtcatca ggtaatacac cttttaaatt agcataattt gatgcatgat tacttctaaa
     4801 tacaattttt tcattggcat ctatattctt tatcatctct ttaatttctt gtaacacagc
     4861 cttatcctct agtattgtaa actctcctgc cttaagtaaa tcgtaaagtt cagtattagg
     4921 ttctaccatt aaactaagta cacctacata atctggtgaa atttttccta acatttttcc
     4981 tgtatcaacg gcatgctgat gtgttttttt agttcctcca agacctgcta ttacagtggc
     5041 tgataattta atcccacttt ttttaacttt tctaccaact tttattaatt gttcactatt
     5101 aaaacctttc ttaatatctt ccaatacttc attgcttcca ctttcaagcc ctaaataaat
     5161 cattttaaca ccaagttttc ttaactctat aagctcatca tcagattttt tctctataga
     5221 tttaggagaa ccatacatag taattctttc acactctgga aaaacttctt ttatatataa
     5281 aattatgtct cttaatttct ccattggtat tatcaatgca tctccatctg ctaagaatat
     5341 tctttctaca tgtttataat atcttctaaa tatatcaatt tcatttttta ttacttctag
     5401 tggctttatt ttaaattttt tagatttgta catactacaa aacgtacatt tgttgtgaga
     5461 acatcctagt gtgacttgta ttataagact ataagcctca cttggcggtc tgtaaagtgg
     5521 catatcgtat tccatattaa aatccccctt gtaataaaat atttattcta ttatattatt
     5581 aatatttact ttaaataata acttataaaa ttatattttt taattttagt ttaagataaa
     5641 ttctttaaaa atttaatgat actattggca gtaatattaa gttgtttttc ttgacttata
     5701 atagcatcat tatctccctt ttgttttcca tagtctccaa attgtgcatg atttcctcct
     5761 tcaatttcaa cataagttgt atcatcagga agtttttgtt ttgattctac aagactttta
     5821 aaattgacta caccatcttt gctcccccat atagatataa ctttttttcc taattctttc
     5881 aactcatctc ccattggata agaagctaaa aatacaactc catcaattaa tttattatca
     5941 cgtgcaaaat ttgatgctac aactcctcct aatgaatgac ctcctattac ccaatgttct
     6001 atgttgttgt aagaatccat aactttctgc gccttattag ttccaagtat agctagatta
     6061 agtggcatct ttacaattac aacctcatat ccactttctg ctatttttct tgcaagtggt
     6121 gcataagatt ctatttctac tttagctcct ggatacaaaa ttaaaccttt agaaactttt
     6181 cttccttttg gtgtaaatga aatgttttct tttacagtta cttcaacttt actattgctg
     6241 attagagctt cttttgccag tttttgaggt tcatatgttt tatttatcca tatgaaaaaa
     6301 ctaagcaaaa tcaatacaaa tagtatacct attcccttaa atatcttatt ctttatgtta
     6361 aattttctat tattcttttt atcatctttg ttttcaacct catcataaag taaaggtctt
     6421 tcgagttcca tagttatact aaatgtatca tatttcttat tgcgttttac ctttacatct
     6481 ttactcataa atctaacccc cataatattt gaatactatt atagtttatc ctaagtaaat
     6541 tgttttttca accaatgaaa aaaatcaata ttttaactat tttcatataa aattcataaa
     6601 tatatgtttt ttgtttttta tatattattt tcttttaata ttttataaaa caaatagcca
     6661 tatactttat tttaaatata tggctattct ataatttaat atctaagcta cttcttttat
     6721 tgaaacttta gttatattac ttattctata catttctttg acaccattta gagtttgcag
     6781 taagtttaga catattatct tgtctcctag agttttagta tttacaatac tctctaaaat
     6841 tacgcttctt ccctcatcat acttatctac attgtaattt gaaatataat tagtatctct
     6901 caatattttt tcaacatctt catcttgtat tttattttta ttaacattta tatatagatt
     6961 atacatatta cttattagta atttctgatt ttctaaaaaa tcttcttgat atttatcttt
     7021 atatatagca tttatcaaca taattctatc ttcaataagt gatggtacca ataataaatt
     7081 ctttatatag taaacatcag ctacattttc tatagactta ttgacttcat caattatatt
     7141 tttaacgatt cctttataca tgtctatcac atgttgatag cctgttttag catcatatgg
     7201 taatataaac ttatttacta ttaatgcaat aattgctcct aatgctacat atgaaatcct
     7261 gcttattgtt aaaacatttg ggtctcccat aactacagct gaaccaagag ctgaaacagt
     7321 tacacatacc attaattttc tataatcaac tacataagag tttatatatc ctgctaaaag
     7381 aactattaac gaccttaatg tactatcttt tattattgaa aataatacaa taaatattac
     7441 agctcctata aatgtacctt ctattctttt tctagacctt tgtatacaat tttctgcgta
     7501 aggttgtgtt aatgaaaaaa cagttaacat tatccatctt ccatccctta aatggaaata
     7561 atccataata aaacccgcta cagctgtagc taaagcaatc tttactgcat aagaaaatct
     7621 tatagaattt aaattaaagt ttttcttata tattgatagt cgtttaaatt catgaggtat
     7681 atttgatttt ctttcagctt tcttttcgtc tcttgatttt atttttttat aatctactaa
     7741 aaactcatat aaattttcta aaacactata aatttctttt aaatttatat ttttagtatc
     7801 ctgagcaata acataatctc taaatcctaa tatctcttta tcagttatgg tatctttatt
     7861 ttctaaacac atcttaatat agtttacttc ttttgttgct acaactagaa catctgattt
     7921 actatttatg ctactttctt ctaaaatatt ttttatatct tcatcttcaa attctttact
     7981 atcctttttg tatctttcta ggattaaatt tattctttct aatgaaaata aaatattcat
     8041 tatgtctata cctctaatac ttatataaaa gtcatctttt ctattatcaa aaataaccat
     8101 tttcaaattt ttagatatag aatttattct ataattacag ctatctattt ttctcatact
     8161 agatttactt atagaactat catcattaat aatatttttt aaaagactaa ttttttctaa
     8221 taattcatca catatagata tcagttcttt atctccaata tttttcatcc tatttctgtt
     8281 cataacaaat tgagcaatca ttattataac tgctccagca gctaaagccg acaatctcat
     8341 aggaaattca cttattccta caggtatact taccataaat atatacatta ggccaaaagg
     8401 tacatatact gctcttttta agtcataact aaatatatac cctattataa ataatgctat
     8461 aaaatttaat aaaacgccta aatacatatt ttgtactgca aaaaatgata gtattcctag
     8521 gattatattt attgctaaat actttagtaa atttttaatt ggagaaatag ttaaatctct
     8581 ttccaatagt gttagcatag ctgttactat accaacacct ataagtgtgt ttttacttcc
     8641 aaataaatat atgaatatag aaataaatgc tattataaaa ataaacaatt ttgtttttga
     8701 tattactagt ttctttgtca ttatatcccc cctaaaaatt tcaacaagac caattttatc
     8761 atatttgtta tcttattcaa aatactcttt tttacggtag gactttaact ttttttacat
     8821 tttgaactat ataatctata tttaaacgta ttttattgca tatatagttt atatattttc
     8881 gtatgctccc atatattttt tctttcaaat attttttcaa aaatataaaa ataactctct
     8941 caacaatact aaaactgtat ttattaagag agttataatt tatacaataa atttaattaa
     9001 gcttttcttt acccaatata taagttccaa gacccataaa taaagctcct ccaacaatat
     9061 ttccaagtgt cacagctact aaattataaa tagctcctcc aatagtaact gtacttattg
     9121 ttggtgaaaa taatgaaaca ctataaattg tcatatttgc tatactatgc tcaaaacctg
     9181 atgttataaa ggcaaataaa cataagaata tcataattat ttttgcagta tcactattag
     9241 ttctaaacga acacaatact gatacacata ccagaatatt acataaaacc cctctaaaga
     9301 aaagagctgt aaatggcatg gatgctttac tagctgctgt atttgcaaaa aattcagcta
     9361 caggtccttt atctactaga ccagttccta caaatataag acctaaaatt aaagctccaa
     9421 ttaaattacc tacccaactg tatgcccata ttttagaagt atcttttata cttacacctt
     9481 tatttaacat accagcagac ataaccatat tgtttccagt aaataactct gttcctgtca
     9541 ttataactaa acttagtgct attgcaaagg ataaccccat tactatctta gtcataggtg
     9601 aacctgcatc agtcaaaagt cctccaatag taaatatcaa aagtatacct attcctacat
     9661 aaagtcctgc aaacgcagaa gataccaaat attttacttt acttgtgttt aataaattta
     9721 tcttatttat agctgcatta gttaatttat ccaaagtttc tttatgcata attccctctt
     9781 ccttctatta aattttaatt tattcaaata tatgttttac tcaatttata gatatttaac
     9841 tccactccag tatatgtttt catacatttt agttatttct ggaagttcta caccttcaag
     9901 cgcccatttt ttaaactcca taaatcctgt tctatcaatt atatatccta tatgttcttt
     9961 tcctcctggt gcatctttat ctatatactt ttctacatat ttgtaagtat taagtattat
    10021 ctttattatg ctattctcat ctacccataa aagaaaatct tctgctagtc tagggttttt
    10081 ctttcctgtt ctacccatta tagctaatct atagtatttt ttctcatctc tagtccatgc
    10141 atttgttggg caatttagta cacattctcc acatcctata catttatctc catctcttac
    10201 caccttatta ttttctgttt ttaatgctcc aacagatatt ttagaacatt tttttacaca
    10261 cgctccacaa tttacacatc tatctttttc atatatgggt aaagccatac caataattcc
    10321 aaaatcattc attctagctt ttatacaatc atttggacag ccagttaaag ccactttaaa
    10381 atgtaaatca tttggaaata tagctttttc tattctttta gcaaatttag ttgtattata
    10441 ttgagccttt ggacagactt tatttcctat acatgctgct atatttcttg tacccgctgc
    10501 tggataacct gcatttttct cactttgatt tatattcatt ttttcaataa caggttgtat
    10561 aattttattt atttcttcca tatcttccat atttattcct aatatttcaa agccctgtct
    10621 tgtagttatg tgtacctgtc cattaccata ctcacttgca attttagaaa ctatagttaa
    10681 actctcaggg tcaataagcc caccaggtac tctaaccctt aaagaagtct catattttgt
    10741 ttttgtaatc ctataagcat ttttcattac ttttttggta tttaaatctc ttatcacaaa
    10801 cttcgccccc taatcaataa gatttttagc atatgaataa tcaaatactg gtccatctaa
    10861 acatatataa gtgttatcca ttttacagtg tccacattta cctataccac aacacatttt
    10921 tctttcataa gaaacccaaa tattcttttc atctaaatct ctttttaaaa attctcctac
    10981 tgtaaacttc atcatcattg gaggtccaac tacaactata gaagtattat ttatattttt
    11041 tatatccaat tctggtatgt attttgtcac taatcctata tttccactat atccttcgtc
    11101 tgctccatct acagtaacta aaatatcaag ttttttactc catctcttca aatcatctgc
    11161 aaataaaaca tcttttggtg atttaaatcc tgctattaat ttaaactttt cgcatttttc
    11221 tttattgttg taaaaatatt caactattcc tcttacaggg gctaatgcac ttcctcctgc
    11281 cactactaca atttctcttc cttcgtaaag agatacatca aatccatttc cataaggccc
    11341 tcttataaaa aaagaatctc cttctttata attaaacaac tcactagtta cttttcctac
    11401 atttcttatt gtaaagtcaa tatagttctc tccatatcct gatactgata ttgggctttc
    11461 accgtattta ggtatagata tctcataaaa ttttccaggc aatacacctt ttgtatcgca
    11521 atttactcta aaagtccatt ctttatcagt atgcttaact atatctaata tttttgcgtt
    11581 tactggtata tatgggttca tttatatttc ctccttacta gttactaaat catttatttt
    11641 ttctatacat tttgaaaatg atatgtattg tggacaggca tcatcacatc ttccacaacc
    11701 aacacacata tgatatccga atcttttttt aaaatcatgt attttatgca tagttttaaa
    11761 tctcattctt tcaccttgtt tttttctaaa agaatttcca cctgctatat ctgtatatcc
    11821 atctacttga caagaagccc aaactcttct tctctcacct acattctcat tttccttata
    11881 gaaaatatcc tgcattgtaa aacatgaaca tgttggacat acaaaattac atctaccaca
    11941 tcctatacat cttgtatcat attcatccca tatagaattt cttatcattt catttgaatc
    12001 aatattttct ggcacatcta cagatattaa attatcagtt acataatcaa tattaaattc
    12061 agtcgtttct ccattaaata tttcaaattc actatccttt atgtctaaat acagtgtatc
    12121 tccttctata tttaatccaa ttgaataatt atcagttttg ttagaatcca tactcacaca
    12181 aaaacagttt ctaaaacttt ccttacaccc tacaagtaca aactttactt tctctctgat
    12241 atttttataa aaataatctt tttcttcgcc attatttaga tatatttcat caagtctttt
    12301 tatcccattt atgtcacaag ctctcaagaa aattaaaatt ttcttgttgt ctaaatcgct
    12361 ttccttaaac tctttttcag taaaataaaa taatacttga tttataggaa gtacaacttc
    12421 ttttggtgag aaatttgctt tcttggtaaa ttccatttct tcaaaagagt ttacctcctt
    12481 gtatcttata acatcagtat ctgaaaaagt acctttaaat ggtattgaaa ctggtgcaaa
    12541 tatcttgtag tcttttttta gataattcag accttcattg aatttagatg aatctaattt
    12601 taatttcatt cttatcacct ttcttatatt ttagttttac ttacttctta tcttgtttaa
    12661 atcttaacat tttattttct atgcttctgt gataattatc acagtttcaa aaataataaa
    12721 aaaatattaa tagagtttat taagctctat taatattttt ttattatcta tattattcga
    12781 ttacaaatct agtcacttaa atacaatcat taaatacaat aaatctatta tctactcaac
    12841 tttttgaata atagagagtc ttatttgctt ttttatacaa tttaggaaag gtaaaataag
    12901 gattaataaa ttagacaata aaaaagaatc tataaataga ttctcccaat aatattttta
    12961 attaattaaa atcctaataa tacccttatt taatcataac taattatttt taaaatacct
    13021 tgataattca gtttctttaa cgtaaaaacc tttattatca atcttaataa gttcttcttt
    13081 ttgtaatacc tttatcattc tagaaacagt ctctctttta cagccaagca tatcagctaa
    13141 atatgtaact gtaatattta catttagtaa agtccattct ccacagcaaa ctccaaattc
    13201 tctacttaac ctatataatt ttgctgcgag ttttttatct acttttatag atatagaatt
    13261 tttcaactgt ctatataaac gtcttattct tctttccata taagaaataa tatcttttgt
    13321 aagttgaaaa tcactttgca taatttctaa aaactcttca atactataat aagctacaat
    13381 tgagttttca aatgcttcac agccaacagt ggagttttta gaagagtcaa atgtaatatc
    13441 atttatgact tctccactat ttaatatgaa aattactttt ctctcaccat tttcacttat
    13501 cttaaaaata gatacctttc cttctaaaag catataaaca ctgtctaagc tatctttttc
    13561 ataaaataaa atttcttttt tttgtaatct ttttagttta gctttttctt taagttgatt
    13621 cttcgttttg gtacttaact tattaaaaat cattacttta tcaatattat aatcttttaa
    13681 tttagacatg taatatctct ccattcctaa gtttttaaga gagctctata aaacattaca
    13741 aatttcttat tttattcatt tttaaacaat tttatagcat ttgtagtttt aatttttctt
    13801 tcaatagctt cattagaaag ttcttttact acttgtgtat atactaaatc aataatgaag
    13861 aattgtgcta atttagaaga tattgaaccg gtttccagta ctgtttctcc tgatacataa
    13921 gataagtgta catctgaaat atcctttaat tcagaatttt tattttcagt aattgatata
    13981 attttagcat tattggctct tgcaagcttt acagttttta taatctcctc tgtttcacca
    14041 gaatgtgaaa ttgcaattat taaatctcct tcttccatta tggaagacat cattatcatg
    14101 gtatgactac tgtcaaaact tacacaatta agacctattc tcataaattt atagtttgaa
    14161 tcctgtgcta ttataccaga atatccaata cctatgaagt aaactttctt tgcatttatt
    14221 ataagccttg cacagtcatg tacatcctta ctattgatta tctccactgt gttctctaaa
    14281 gtggttacat ttgaacttaa aagttttttt gctgtatcta aagctggctc atcattttgt
    14341 atatttttat ttataatatt ttttttattg atagttgata tttcttgtgc taaagtaact
    14401 ttaaaatcct gtaatccatt aaaattcatt ttttttacaa atctagttat ggttgcttca
    14461 ccaatattgc tttctttagc tatttgtgat attggtttat aaaacacatc atctatattt
    14521 tcttttatat aagctattaa taatttatct gactttgtga ctttaaaagt tggtgattcc
    14581 aattgttcta aaatactcat taaaaaccct tctattcttt atattttgtt taaaaaatta
    14641 tataatgccc caagcattcc cgcatcattt tgtctctttg caaattctat attagtgttt
    14701 ttgtaaactc tctctataag aacctccttt aatgctttgt ctatttttgg ttttaggaac
    14761 ttttcttgtg ccataatccc accacctaaa attactacct ctggatttat tacataacat
    14821 atatttgcga ttccaactgc taatgatttt atcatattat cgagttcttt taaacaacct
    14881 tcgtcattat tctttgctaa atcaaaaatt atttttccat ttaattcatt ttcattcaaa
    14941 ttttttattt ttgctacttt tttaattaga ctgctagtag atgccaattc ttgaaaagaa
    15001 cttccattta tattcatata tcctacttcg ccagcactat tactaaaccc atttatcagt
    15061 ttattgttta ttataataca tccaccaatt ccagtaccta ttgttaaaca tatagaagat
    15121 gttgcacctc tacctgctcc aagccacatt tcaccaagtc cagcacaatt aacatcattt
    15181 tcaacttcac attttatatt aaactctttt tctatttctt tttttaattg cataccctta
    15241 tagtttggaa ttaattcttc taatgcaaat agtattttac cttcaactgg gtcaaccata
    15301 cctgcagttg atatgcatat accacttatt tcattttctt ttatatactt ttttactata
    15361 ccttttattt tagataatat tccttctcca cctttttctt ttgcttcagt atcaagactt
    15421 gatttatcaa ttattaatcc atcttctcta ataaatccat attttattga agtacctcca
    15481 acatctatac aaacgtaatt tttcataaca tatctccata taaattattt ttataaattg
    15541 ataacactac ttaaactctt atattaaaca aattttttac ttatcttttc caattcatat
    15601 atataccttc ttgcttctga taaatctatt gtatcgctta ataattcttt ttccttagtt
    15661 gtatgatatt tataaatatt tttacacaag tcttttccta atatattaag accttcttga
    15721 gtgtaatgta catcatcaat agttaaccct ttatcatgaa attgcatagc aattttgctt
    15781 cctacacata atatatcaca ttcattacaa gcagactcct gtgctgctgc aattcgtctt
    15841 gttctaataa aatattcatc ttctccaagc caataaccag ttaaacttac aaacatttta
    15901 tcaatcatac attcttcttt aagtctataa gcaatctttt ttagactttc tttatagtac
    15961 aatgcatcac taccatattt cgcatcactt tcaccttgaa tccaaataac atatttattt
    16021 tctatattat aatgtttact taaggtagca cagcctgcat taaatttttc tatagtgtca
    16081 tttaggaacc agttattatc atgattccag ttttttattc ttgaaccatc ttttgcattg
    16141 tgaataaaac aaactttatt tccagtaagc ttattccatt catttgaaaa tgcaggtgct
    16201 atagtaccat caccttctga agtttctagc tcacatctca tatttataat ttcatcagta
    16261 cttaaatatt caaaacaatt ttcatttgga atgacactct ctttgggatt ccctaatcct
    16321 ctagcattgc tttgtcctat taataagaat acatctatat tttccataag ttaactcctt
    16381 tacaaaattt taaactttta attattttca atttccttat aaaaaactaa ggctgaaaat
    16441 agtaatctaa ctaaaattta cgaagtctca ctaatcgctg aaagttaaat cactattttc
    16501 agccctagtg gttatataaa ttataattat ctaaccaaaa ccttaaaaat agcttttttg
    16561 atattttctt tttctaaaac ttttattcct gtcatatgag catcttctgg ataacaaact
    16621 aaaaaatcgc cttttctaag ttctacatat ccattatttt taccatcaag aggtaaaaaa
    16681 tctccctctt cttcatatat tttttgttct aaattttcta taaaatttat atctattcgt
    16741 tcacatccat caagcatcaa atgaacatct atatacttct tatgagcttc ccagaatcta
    16801 tcttcttttt cacaagtttt atactctaca atattcacaa aaatatcatc accatctatt
    16861 gtataagtac ctttttcata atctattaat gaattatctt tagcatattc aaaacatcta
    16921 agtaaatctt catgcaatgt tgaatatgtc ttactatgat ttatatttcc aaatatcata
    16981 agcactatct ccctatataa ttataaagtc tatttttata cttttatata taaagtatat
    17041 tatacaatct tatagagtaa ctaaattatt tatctaatca ctctataaga caatttatca
    17101 tttaaatatt atttttcata ataaacagta gtctcagctc ttggtaaaga tacttttgct
    17161 ttaactttag cttctattgc actaaatatt gtacctacca ctacagaagt agttattgtt
    17221 attaaagaat atgcccaaga agttacttct ggcatacagt attttaaata aacaaccaaa
    17281 attgctgata ctataaaccc aacatatgct cccatcttag ttgctttttt acaaaatgca
    17341 ccaagtacaa atattcctgc taagacacct agtactagac ccataaaact attgaaccat
    17401 tcatatgctg actttatttc tccatttgct aatactattg caacaactat agaaagtata
    17461 cctacaccta atgatatata ttgtgctatc ttagtttgtt tttccatact tatatctttt
    17521 gttatgatag tttgtatatc taaagtccaa cttgtagcaa ctgagttaag ccctgttgat
    17581 aaagttgatt gagaagctgc atatattgct gcaagtagta ttcctgttat acctactggt
    17641 aactcataag ctatatatga tgcaaatact tggtcttgtt gaactgtttg agctaaatct
    17701 ggattttgag tatagtatat aaataaacaa gttccaatta aataaaatac tgttgcaagt
    17761 cccattgata aaacaccatt tccatatgtc attttattaa gttgctttat atcagttgtt
    17821 gtagtaaacc tttgaactat atcttgactc gatacatatg atgaaaaagt attaagtcca
    17881 gctccaacaa atattataaa tgcacttgta gatagtatat ttttatcaaa cataacttca
    17941 ttacttgcta agaacttgtg tccagttgta agagtatcca ttactgttcc aaaaccacca
    18001 tttatacttg ctattaaata gaataatgtt cctgtaacac ctactattag taccattcct
    18061 tgtataaaat cggtccataa aacagctttt aatccacctg tatatgagta aattattgct
    18121 attacaccca taactattat cagtacattt acaggtattc ctgtaagacc agccagaact
    18181 attgatggaa gatacattat aatagacata cgtcctattt gatatattat aaacattaaa
    18241 gctccaagca ctctaagacc tttgctttcg tacctcattt ctaagtactc ataagctgta
    18301 tcaatttcta acctactata tagaggtaag aaaaatttta ttgttaaagg tatagctata
    18361 aacataccta attgtgcaaa ccacaaaatc caagtcccac cataagaatt tcctgctaat
    18421 gataaaaacg atattggact taataatgtg gcaaatattg atactgatgt aacccaccac
    18481 ggaatagttc catcaccttt gaagaactct tttcccttca tttccttttt tgaaaataac
    18541 aatcctgcaa ataaaactgc caataagtaa accactagta ttgtaaaatc tatccaagta
    18601 aatcctacca tttgactaat cctcccatac taaaagtatt ttattaaaaa tactttctgt
    18661 atatttcttt tgctcttgat ttcatttcat cagttgcttc tttcataggt tgtctacagt
    18721 atccagcctc aacaccttgt tcttcaagta gcaatttaat tgtttgatat aatccatttc
    18781 ctaatatatc tgttattaaa tcattagtca catgttgtac ttcaagtgct tctgatattt
    18841 tttcattctt agttaattca aatatttgtc tagctctgac accgtttaca ttaaatgtag
    18901 aaccaattgc cccatctaca cctaaaactg tagctggtaa catcatttca tcaaatcctg
    18961 caaatattaa tttatttggg aatgtttttc tcattctctc taataagtag aaatctgctg
    19021 ctgtaaactt aacacctatt attttttcat tttcaaataa ttctccaaac tggtctaaac
    19081 tcatatcaac tccagttaaa aatggtatag agtatattat taatctatta tctacagaat
    19141 ttattattgt attataatag tgttttattt cttcaaaatc aaacttatag taaaaaggtg
    19201 taacagcact tattgcatca tatcctaaat cagttgtaaa tttagcaagc tctacagctt
    19261 cttttaaatt gactgaacca acttgagcta ttaattttat ttcttccttc acttcatctt
    19321 tagctatttc aaatattctt ttcttttcat cagttgaaag cataaagttt tcccctgtac
    19381 ttcctcctac ataaagacca tctactttac aaacatctat attatgtcta attatttgtc
    19441 ttaacccttt ttcatttata tttccttcct tatcaaatga aactaataat gctgaataaa
    19501 ttcccttcat atctgttgtt ctcatatctt tacctccaat tttaattttc aagtatagtt
    19561 aaatataata gttttttaat ttataaatta atttttaatt aatttcaatt gctttaacaa
    19621 atttttctgt tattaattgt ggtcttgtta ttgctgaacc tacaactgat gaatagactc
    19681 ctagttcaaa aacccttttt aaatcttgag gagtatttac ctttccttct gctattacag
    19741 gtatttctaa atctttaact agtctttcca ttaatacaaa atctggacct tctaacgttt
    19801 tagtatatgg agtatatcca gatagtgtag ttgaaataca atctacacca tattcttgtg
    19861 ctttgatagc ctcatcataa tttgaaatat ctgccattac cagaacacca ttttctttta
    19921 tatactttat aagttctttt aagtcttcat tatttggtct aactctatta gtagcatcta
    19981 aagctatcat ttcacaccct gttgtcaaaa gttcatcaac ttctttttta gttggtgtta
    20041 tatatatatc tgaatcttca taatttctct ttataatacc tataacagga agtccagtaa
    20101 ctttttttat ctcaataata tcttcaactc cttgagccct aattccaaca gctccacctt
    20161 ccatagcagc cttagccatt ctccccatta taaaaggact atgaagaggt tcattttcta
    20221 aagcttggca tgatactatt aatcttccct ttaccttatc tagcattttt tcaattacct
    20281 catttctgaa atttattttc ttgatttatg tattaataat aacatgaaaa ctttttcttt
    20341 gcaatatttt ttcatatttt tttcttaact ctatattttt actgatttat tctatatatt
    20401 agtctgtttt ttatacttaa aagaaatttt atttcatttt tttggtgttt attttcattt
    20461 tgtataacca ctattatatg tattctatat aaataatttc aataaaaaaa cccatgtata
    20521 ctatacatag gtttcccaat attattctaa atccattata atttttcttc cacaacatgg
    20581 acaaaattca gcctctgtat ctatctcact ttcacaataa ccacaaacta taaaatcatc
    20641 acattcattt tccaattcaa attttttgcc acattcagca caatatttat catttacatt
    20701 tccaacatag ccacattcac aagttacatt actttctacc atttccattt cattaatttc
    20761 catatttttt tcataaatta acttatcaag ttctagtaac tcatcacaga atttatcaaa
    20821 actattatca tcaatagaat cttctctaat tttttgatat gtcaatattc ccatttccaa
    20881 gaatatcttt gctttctttt cttggatatc atcaatctct ctatttaact ttgatttttc
    20941 tttatataat tcaactttaa attttccatt accaaacttc ttcttaacct tagaaaattt
    21001 atcatctact ttattattaa tatttccttc cacagatgtt ccctccaatc atatttaatc
    21061 agctgagttt agcttataac ctattaaaga tatcacaaaa ctatatataa atgaaattac
    21121 aatagcttgt aagactttaa attgcattat taaagttgct ccataactag ttgtattaaa
    21181 gaaattaata ttactatcta gtataaatgt actaaataaa gccaacatcc ccattaaaaa
    21241 agcataatat atactaaata ctactatagg ttttatacta tccgtattat acttaaatct
    21301 tagcttgtat ccatttaata ataatattaa catagataat gctcccattg cataaaacat
    21361 taatttagta tctccaaata aagatgaaga actcaaagta aacattgata ctgttgaatt
    21421 tattatggtt actgaaattc catttgcaaa agcccacata tagctagcta tttgtggcag
    21481 tatagtaaat aaatttaatc catttgagta actactcata tctagttcat ttaagtaact
    21541 actatcagat atagttagta caaatagtat tattaatact aaaacataac ctaatataaa
    21601 tgtttttata gaatttgaaa agagagataa atacatattt tccttttcat aacttttttt
    21661 ataagtagtt atgtatgtac atataaaccc taatacaaat ccatttaaaa ggacactaaa
    21721 aaattcataa ctatattcta atgcatatcc atattctaac atactatgtg aactagtttt
    21781 tacattagta aaaatagata aaatagctaa aactaatcca taaaaaattc caacacctat
    21841 agaatttgct aatacagatt ttgaatctct acatcttttt ctcataaaaa ttaagtttga
    21901 tattaataat accaaaatag gaattataag taatattaac aaacctatat tggcatttat
    21961 aaacccagaa cccatcatgg tagacataga tacactaatt tgacctaagt tgagagctag
    22021 gattatatgt gctggattta ttaaataact aatatcatta aattgaatag ttataatagc
    22081 tttaaatatc aatgcaataa taaataatat aaatatggtt gtaaatgttg ttaaaaatac
    22141 tcctctttta tttgcatgat atgaaagctc ttttatttta gattttaagt ctagttttgt
    22201 ttcaagtggt cttaatgatg ttatttcata aagttcattt ccacaaaatt tacagtaatt
    22261 atccttagta ttattttctt tattgcaact agaacaaatt ttttcttctt tatttttaag
    22321 agtgatatgg ctatttttta tttttctagt tggttcacct gtcgttttgg aataattatt
    22381 atgtgaataa ttcatgttat ttattttctt ttcacccatt tttcccctcc aagttttact
    22441 attgtaaatt attaaataca actatatcat ataaaactta attatacctt aattggatat
    22501 atttatctat tttatttgtt tattgctgtt gttttttaac aggtcttgat atttaaatat
    22561 cttgttaatg ctaactttat tatttacatt ttattatgct taatttaaat ttattttatt
    22621 ctttattttc agtagcaaac tatctttaaa tcttaattat aataaagtat taaccaataa
    22681 agttattcaa cattagctaa taaattttat ccattacaat tttagattgt tacacacaat
    22741 atattttgat ataatcaaat tataaacaaa gtattccaag tatctaaaga cataaaggaa
    22801 tacttatttt tatgctttat ttttaatgga ggcttatatg aacttagaaa aaattaaaaa
    22861 attttgggga tttcctctag ataaaaaaca taaagaaaat gttgaaaaag aactttgcaa
    22921 ttatctttac catactggta aaatcatttg cataataata gtaatatctc aaataattat
    22981 gatgatatca atctccgcta gagagggagg tccttttgcc acaccaagac gccaatggta
    23041 tttttatatg tatgtaacac tattttgtgt atcttctgtc tttatgtttg tattttctta
    23101 tctttggaat aaaaaaaagg attgttgtac tttttatata aatttatgga taatttatgt
    23161 aacttttttc tgcctatggg gttgtgtaat tactctactt gaccagttag gtggaaatga
    23221 cctaagtgta tttagttaca ttatgctagc agctgcagct ttctcagtat taaaattagg
    23281 agaatcagta atagtttttg gaggatgttt tttgtttctt aattttttct tacctggtat
    23341 tcaaactata ccaggcaatg agtttagtaa tatcgtcaac acatttttta taacatccct
    23401 tgccgttttt gtttctacaa tgctatatag aagtcgtgta tttacttact atgacaaact
    23461 tttaattagt caacaatatg aagaaatata tcatataaat aatttactta acgacaaagt
    23521 catgacagat gaccttacta aaatgaataa tcgtagatac cttgaagata ttctacaaaa
    23581 aaaattaatc agccatgcaa atcaagaacc tataactgga atgatgatag atatagatta
    23641 tttcaaacaa tttaatgaca attatggaca tcaaaaggga gactattgtt tacaaaatat
    23701 tgccaaagta attttggatt ttacaagttc tgaaaatgaa catgctatac gatatggtgg
    23761 tgaggaattt tttatatgta tttttaactg tgatgaggaa gatgctaaac ttaaatcaga
    23821 atgtttacga aaaattatag agacctgtaa ttttgagcgt gacgatatcc ctttaaaatg
    23881 tgtaactgtt agtatcggag tctacacaaa taaaattgaa aggacaataa cgctaaatga
    23941 gtttataagt aattgtgata aggctctata tactgcaaaa gaacagggac gtaattgtgt
    24001 tgcattttat taaaaagtta catactatta cataaaccta taagtattat attgcaaaat
    24061 aaaagtaacc aaattatata tttatagtac aataaaaata acttgcatat ctctaaaata
    24121 gataaatatg caagtcattt tagtgtttac acttaaaatt atataagttt tattatatat
    24181 aattattaaa attcagcatt tttaggagtt cttgggaaag gtataacgtc tcttatgtta
    24241 gacatacctg tcatatacat aattattctt tcaaatccaa gaccaaatcc agagtgggta
    24301 gcagtaccaa attttctaag ttctaaatac caccaataat cttcttctct taatcccatt
    24361 tcattgattc tatctagtaa tacatcttct ctttcttctc tttgagaacc tcctacgatt
    24421 tctccaactc caggaactaa taagtccatt gctctaacag ttttaccatc ttcattcatt
    24481 ctcatataga aagcttttat atcttttgga taatctgtaa caaacactgg acaattatat
    24541 atttgctccg ttatatatct ttcatgttca gtttgaaggt cacatcccca ctcaacagga
    24601 tactcaaagt catgaccaga ttcaattaat aattccactg ctttagtgta tgttattcta
    24661 acaaactcag agtttactat cttatttaat ctttctaaca atcctttatc tataaaacta
    24721 ttaaaaaatt ccatttcttc aggagcattt tctaaaacat agcttataac atattttatc
    24781 atatcttctg caagttccat gttatcttca aggtctgcaa aaactatttc tggctctatc
    24841 atccaaaatt ctgaagcatg tcttcctgta taagagtttt cagctctaaa tgtaggtcca
    24901 aaagtataaa catttctaaa agaaagtgcc attatttcgg catttaattg accactaact
    24961 gttaaattag cctcttttcc aaagaaatct tgagtatagt ctattttgcc atcttctgtt
    25021 tttggaatat catttaaatc catagttgtt attctaaaca tttctcctgc accttcacag
    25081 tcactacctg ttatgattgg agaatgtgca tatacaaagt ttctctcttg gaaaaatttg
    25141 tgtattgcat atgcagctat tgatcttact ctaaatacag ctgaaaaagt attacttctt
    25201 ggtcttaaat gtgctatcgt tcttaaatat tcaagtgtat gtctcttctt ttgtagcgga
    25261 tatgaactat ctgattcgcc ttctacaact atgctttttg catgtatttc tactggctgt
    25321 ttagctcctt ctgtagatac taattctccc tctacaagta tagatgagct tattgctaat
    25381 tttcctacct ctttaaaatt ttctactttc tcatcaaata ctatctgcat atttttaaag
    25441 aagcttccat catttagctc tataaatcca aaatttttag atactctaga cgttcttatc
    25501 catccagcta cttttacagt cttccctatg tactgttctt tttctctata caattctttt
    25561 actgttataa attccttttg cattttaaat cctcctagta taattgttat taatttcttt
    25621 taaatatagt ttcaataaaa aaagcccttc atccctatat aaagggacga aagactatta
    25681 ctctcgcggt accaccctag ttgtcataat gacctcttag ttaagcaatg cttaaagcct
    25741 ataacggtgc cttccgtcta agtctactta ctaaataagc tttcgattag aaactccaag
    25801 atgttcttca atataaacct cgtattgagc tttcaccatc ctcaactcgc tagaactaca
    25861 ttttatatct actcttctct tcatagtatt tatcttttat tatttctgct aattaacaaa
    25921 attataccaa tttataaatt tttagtcaat aaatttatat aattgatact gattgctatt
    25981 taaaatataa taactctacc ttgcaaaatg acaataaaca cttatcttta ctacttcagt
    26041 ttcaaaactt ttataattta cttccattat caacccagtc ttttgcttct gtaacaccct
    26101 taattgaagg tattgaaact ttactatgag gttttaattt ttcaacatca gcccatgctg
    26161 ctgtcgactc atttccaact aaaagtgaac ttttaagtct tttattatct ttacctttta
    26221 atgctcttgc ttttttattt tccaaaacta tcacctctat tatttatttt gtaatagttt
    26281 tagcaatttt tcaaataaaa ttcataagtt aaaattataa tgatttttaa gtcaataaca
    26341 tatctttttt atactaaatc tataattatt tttatataaa aatagttatt ttatatatac
    26401 aacatataaa actatttttt aatttttata tttactctaa ttcaattttt tgttatctga
    26461 actattaatt aactataaat ttatgcagat tattatctat agagtatttg ctatttgttg
    26521 aattgtattt tttaagttta aaatcccata tccttgtgat acatttggat atgtatatat
    26581 ctcaagcttt gtagctccca atatcaaata tgtctttaaa acttgtgtaa acaatgataa
    26641 tcttggtata ttattctgtt tttccaaata ttccattagt aaagctaaaa cacctgtgac
    26701 tatagaactg ctcacaccgg ttcctgttcc tgtattatac gttccatttt tatatgtaga
    26761 tattatatct acacctggag ctactatatc tggcttaatt cctcttcctc ggattggacc
    26821 ttttgaagaa cctatccaca tgctgtcagt cttattattg aacgtaccaa ctgtaattac
    26881 atcatcacta gcagcataca tagttattgt agctactgaa tcagggtcta aaaaccttgt
    26941 atctggagct atcaaatttt tatttggcaa gtatatatca tattctccac ctattataag
    27001 ttctgaagtc aatcttaaag tccatactcc aggttttata tctcttaatc ttatttccaa
    27061 attttctttt ccagaagtaa tatatggata aataaatctc attgcataag tagtattttc
    27121 taagttaaat tttcctctat atatataaaa gtctggagca taccttatgt catgactaac
    27181 ttcgcctgaa ggagatatta tctgtgcacc tactttatct ggaccattag tatttagtgt
    27241 tatatccagt gcatagtcat ctccatcctg tattatcaca tcttgaactt cacctacact
    27301 actaaatctt ccagaatagt gaatatctgt attaccttga tttcctgcgc cactcactac
    27361 tactacacca gcactactca atatattaaa agtatctagt attgaagtag ttgctacagc
    27421 tcctgactta actccaatag tcagatttat tattagtggt ctattttctg ttcttgctat
    27481 attagtaaca tacgttatag ctgctaaaaa atctgaaaca ctgtaattta tccttccagc
    27541 ataataagta cctatataag attttaattt aactactatt aagtctgatt ctgtagtaat
    27601 acctctatac ttcgaattta cccttccatt tccagctaat ataccagaaa ctaaagttcc
    27661 agtacctata ttatcttgac tcaaacttcc atcatttcta tttatggcta tatttaactc
    27721 acttcttgta aattcacttc caaaaataaa accttctgga ggtggatttg tatttgcttc
    27781 ttggtcccat aaatataaaa ctttactggt tccgtcatca tttataaaat caggatgcaa
    27841 ataatctata ccagaatcta taactgctaa taaaattcct cttccggtta tatcattata
    27901 tggattttca tagatatact cagttccagc agccgttgta atggtttctc cattatctac
    27961 attattggtt atttcaatta aactgctcat tggtgcagat tcttcccacc aagcaacctg
    28021 tattatatta tttagaatag tttcatcaaa atctataggt acatatatta ctgcaagttg
    28081 actatttaaa accatatacc tatttattcc attttcttgt agtgcagact ctatatcacc
    28141 ttgataaatt atacaataag atttttccat aaatccctcc tatcttaaaa catcaaacat
    28201 tcctctaaca tccaaaagcc catatccaga atttgtattt ggatatactg tatttgaatc
    28261 ctttctagct ccagcttgca taaacgtttt tattttttga acataggctt gatttggata
    28321 tctaccatca acaaaagtat attgaaaata cattgctgca gcaccagctg catgtgcact
    28381 tgctgctgct gtaccagtta tagttgcata ggtattccca ggataagcag ctattatatt
    28441 aacaccaggt gctactatat ctggttttaa tctgttttca atagttggtc ctcttgatga
    28501 actttgccat aaactactgt taatagtatt gtaagctcct atagttatta aatcatcttg
    28561 aatagcagga taatttatag tataaaaagg gtctacctct ctaaatctag ttccactttt
    28621 taaaagtttt ctatttggaa ggtataagtt atatctccct gttataatat aaacccctac
    28681 taatcgaatc ttccatacac ctctttttgc attctttaaa gtaacattag taaattgctg
    28741 tccagaaaaa gtagttggat atatatacgt tatagaatat tcagtccctt ctaagtcaaa
    28801 taaacctgtt actttattat aatttgaaac tccaacagtt ttactttctt caccagtagg
    28861 agatactatt attacgtcag ctttatctgg cctacttaac caaagttcta atgataattc
    28921 ttcctcttct tcatttaact ctaactcaac ttcaacagag cctccaacat gtgatattat
    28981 tccagatgta tgtgtttgtg tattgccctc attccctgct cctgctgtta cacataaacc
    29041 tctagtaaaa aatgcttttt cactattaac cctattggtt aaaccagcta aactactggt
    29101 acctaaagat acatttataa ctaacggtct tcccagttca aaagctttat tatatgcata
    29161 ttgagatgca gcaaataaca ttgcactatt ataaaaacct tctatcttac caagttttat
    29221 tactattaat tcagaatctt ctgctacccc tgcatactca ctattcacat ttccaagccc
    29281 tgcacatata ccactcaaca tagttccttg accaacttcg tcctgagata aactagggtc
    29341 atttgctgca atagctcgat ttatatcctc tcgtgtatat tctgtaccaa tataaaaacc
    29401 atctggtgga tttccttctt ttgtttggtc ccatagatat actatttttg aggtaccatc
    29461 tggataaata aaatctcggt gtagatagtc tattcctgta tctgcaattg atattagagt
    29521 acctcttcct gttatattaa tattaggatt atttttaaag aaatttacgc ctatttcttc
    29581 tgttgcaact actcctccaa aagtacctct attaatttct ccaagcaatg tcatctttgt
    29641 agttggtata gttcttatga ttgaaggaag ttgtaaaact tgttgtatgc tattatagtc
    29701 tgtattatct atagatagta cacctaatga atcacttatt tttaaaaaat tttgactctg
    29761 acctaaccca gctaattctt cttcaaattc aggagtatgg actacatcta ttcctgatag
    29821 tattcctgac tgtctactta tatttttact tatatacttt tccttctcta acccattatg
    29881 tatttgtaca ttataaccat ctatgggtat ataattattt gcctcatcca taaatgactt
    29941 attaatactt ctatatccaa tatcctctgt ttctaaatct tgatttatgc tagatagagt
    30001 gtacaaatct acatctgata aatttaaaaa accaaatcct gatgaattat ttgggtaaga
    30061 ttgattgctt aatcttcttg caacttttaa aagtaatgcc ctcaatttct gtgaatacaa
    30121 aaataaatca tttccattta caattcccca ttccataaac aatgagcaaa cccctgtaac
    30181 atgaggagtt gccatactag ttccagttaa tgccccactt gtacctcctg gtaaaaaaga
    30241 tactatatct tcacctggag ctaataggtc aggtttaaag acgcctaatt gtgtatctcc
    30301 ttctccagaa aatatagata ctatgtctgt tcttgaattg aaactgccta ctgttataac
    30361 tctacttgct gttccaggaa ctgttacagt aagctcttga gtaggaatca aaaatctagt
    30421 atttctattt agtccttcag aagttggtaa atatatattt acattacctg ttactatatt
    30481 tattggttca aatatgattc tccataatcc tggagttatt tgtgtatttg aacttaattg
    30541 caaagtaact cttcttgtaa gagaatatgg tgctatagga taaaaataac cagttattct
    30601 agtttcaccc aaggtattcc ttatttcacc tgaagttaga gatattgttt gtgtttgatt
    30661 atttgatggg tttactaaat gcacactaaa atcatcaaca aaatctggcc atatatttac
    30721 atttagtata cgctctcctt ctccaactat aaactcaact tcttctgtaa tattatttct
    30781 aagtctaatc cttttatgac cacctttatc tgcattattt ccagccgcta caactatatt
    30841 atttttccaa aataaacaca tatcatctat atattgttca aataaagacg ttcctctatg
    30901 tgaaccttca ttgcttccat aacttatatt taatgtaaca ggcattttta actccaatgc
    30961 tctatctaaa ataaatttaa ttgccctcat aaactctgta cttcttgaaa aaatatcggt
    31021 ttgtatattt ccaactctca ccactattat tctggcatca cttgcaatag ttgcacaaat
    31081 acctgcaaca tgtgtcccat gtaaactagt tgttgaaata ggtatataca tacttccatc
    31141 tattgcatta tttatatctt cattagtgta taatgttcct tctctaaaac cttctggtgg
    31201 atttccctga atagactggt cccaataata taatatctta gacctaccat tactatctct
    31261 aaacacaggt aaagtataat ctattccaga atcaattata ccaattatag ttcctttccc
    31321 agttaaacca gttctatttt taaaccctgt tattcctgta cttgaaaaac tttgtacatc
    31381 ctgagtttgt aatacaaaag gcttttctat aaattcaatt tctggataag ttaaaagtgt
    31441 atttacatct tcttcattac ttgatgttat tattgcatat gatgaattaa gtatctctac
    31501 tgatacacct agttcttctt ctaatctcaa tatatctcca ttgtatttta caattaattc
    31561 ataatttatt ataatcacct cgacttctaa aattattatt aatgtatatg ttctatgtaa
    31621 gtctaaaatg tatcagacta tataattttt aagtttcaat tatataattt ataatagaga
    31681 tactaaaaaa ataaataatg atggtacaat tttgaataaa tcataccatc atttatattt
    31741 actttatctt gaaaccatta aatttttcag tgctttctca agacctttta cagtcagtgg
    31801 aaacatatta aattcacttt gtatcattct ttgagtttga taccaataat taattgaatc
    31861 ccatccatct ctcagttctg gattcatcca tacagtttta ctgtactttc tcctaaacct
    31921 tttaagccac tctataccag gtgtgtaatt atatggacca cgatagttac caccaatatg
    31981 aagtaactca gaaggtgaca tagaagcatc tccaacaatt ataactttat agtttttatc
    32041 tatatttttt aatacccatt cagtattaat agatttactt aaccaacatt caggtgttgt
    32101 aaataatcta tcataaatac agttatgaaa atagtatatc tttacatctt taaaatgatt
    32161 tgatttactt acagactgaa ataatgtatt gcataaagtg ctataccctc tcattgaacc
    32221 acctgaatcc ataagtaata aaagttttac tgtatttttt cttggtttct caaaaaacag
    32281 ttttaaataa cctgcattat tacaagtctc ttcaatagtc ttatccaaat caagctctgt
    32341 ctttggagca tctattctag tagaaaattg acgcagtctc tttagtgcaa cttgaaattg
    32401 acgcatattt aaaacttcat catctctaaa atctctgtat tttctttctc ctgcaacttc
    32461 aagaacagct ctaccataag tagaatttcc acctatacgt ataccagttt gcccttttcc
    32521 tgaatgtcct aactcagaag ttccccctgt tcctatccaa taattaccac cattatgagg
    32581 agaatcttgc tcttttattc gttcctctaa tttggctctt aatttgtcaa gatttatatt
    32641 tggattttgt tctaaccttt caaactcttc taaatctata tctggttttt taagccaatt
    32701 cataatctct tctggaattt cctcttgatg ttctatacct ttaaagtact ctaaaaatac
    32761 tgtgtcaaac ttatcaaaat cactttcact ttttattaga atcatcctac aaagatagta
    32821 aaaatttgaa aagtttgaat agcacagtcc tttatccaat gcttcaatta aagtcatcca
    32881 ttcatttaaa gatacattta ctcctcttga cctcaataaa taaaaaaatt caataaacat
    32941 aattatccag ctcctattaa ctataagtgt ctttgcatag attcaatatc ctcattattt
    33001 ttaagtagta ttcctgcaaa aggaacttct ttttctattt tttcaatagg tattccactc
    33061 aatgttaatg cttgtatcca gtcaattaat tctgatgtac tcggcttttt ttgtatatcc
    33121 tttaaacttc taatccaata aaaagtagtc attacttgtt ccaataggtg ttcttctact
    33181 ttatcaaaat gcactttgac tatttcctcc atcatatctc tatcaggaaa ttctatataa
    33241 tgaaatatac atcttcttaa aaaagcatct ggaagttctt tttccgcatt tgaagttata
    33301 ataactattg gtctttgttt cgctcttaca gtttcttttg tctcatttat gtaaaattcc
    33361 attttatcca attcccaaag caagtcattt ggaaattcta aatccgcctt atctatttca
    33421 tctattaaaa gaattacttg ttgatttgaa ctaaaagcct ctcctaattt accatatttt
    33481 atgtacttgc taatatcatc tacaccttct cctccaaatt ggctatcata aagtctttga
    33541 acagtatcat atacataaag cccctcttgt gcttttgtag ttgattttat attccaaatt
    33601 actaaatttt tttttaattc atttgaaatt gcttgtgcta gcatagtttt acctgttccg
    33661 ggttctccct taatcaaaag tggtttttca agtgcaatag caacattaac tgatgccatc
    33721 aattctggtg atacaacata atcactactt cctctaaaat tagatatctc tttttttatc
    33781 ataaattcta ctccttttaa acagtatttt ctaaatgtat atatacttta ttactatttt
    33841 tgatataaaa caataatgta atacatttgt atagtattat tctaaaattc tatatctaaa
    33901 taaaattacc tctaaaatat ttaattttta tctttatttg tcataattaa atgaaatata
    33961 tattttaaag aataataaaa gatagcttat tacacaaaat ttaaattata aaaacttagt
    34021 ttaattaaag gcattatttt ttattttaga ttatatatga acataatata aataattttt
    34081 attattttag ccataaacat aaagttttaa cgtatttata atttcatatt aatcagacta
    34141 tattaatact gctttttatt gtataataag ctataaatat taactttaac ttagatttaa
    34201 gtatatctaa atttaataaa tataagaaag gttgtgttat tttgcaagat aaaaaaattt
    34261 atctaaatat tgtactcact gtagttgttt catatatctt gattaaagtt attgataatt
    34321 acaaatattt ttttggagtg ataagtttat taatgtcact actaacacca tttataatag
    34381 catttgtatt agcatatata ttcaacccac tagtaaaatt cttagaaagt aaattaaatt
    34441 ttaagagaat atattcatta cttcttactt atggtgtact catagttata ctaatttcct
    34501 ttatattatt tacagttcca tccatagtaa atagtttagc tgatttagtt gctcaaattc
    34561 ctacatacat agataaaaca gaacagtttt tatttgactt aggcaagagt ttacaatcag
    34621 ttgaccctaa tacattaaaa gaatatggtg acaaaattat gagtgtaatg cctaaattta
    34681 gtaacttact tattggttca cttggcggaa tatttagcac tacattctcg gttggaaagt
    34741 ttatagtaca atttctttta ggttttataa tttgtttcta tatattatta gaaaaagaaa
    34801 aattcttact atttacaaag aaagtagttt atatttcttt aggtaaaaaa tatggagact
    34861 ttataataga actatgtcaa agcttaaatt taaatattgg taaatatttt acaggtaaga
    34921 ttttagattc ttttatagtt ggagtacttt ctggaattgg tctttacttt ttaaaatctg
    34981 aatatgcact gttatttggt acaattatgg gtgtcatgaa tatggttcca tattttggtc
    35041 cagtaatagg tatggcacca gttgtaataa ttaatttatt ctccaatcca acaactgctt
    35101 taacttcttt aatttactta ataataattc aacaagtaga agttacattt atagagccaa
    35161 aaatcgtagg tggacaacta ggtcttagcc cattctttac aatcttagcc gttactgttg
    35221 gcggaggatt ctttggtata ccaggcatga ttctatctgc tcctgttatg ggcgttataa
    35281 aaatatattt ttgtgagttt gtaaatcgta gacatgataa aatacaaatg gaataaaaat
    35341 acaatttaat tacgattttg taatcaaaag ttacagctgt gtaactgtaa tattattctc
    35401 tttaatggta atatttaatt ataggaaaca tacaatatta ttaagtaatg aatcttatat
    35461 aattaaacat gaaagagggt tttagtatga aaaaagcact tatatcttta ttagttttat
    35521 cttgtttgtt attaactgca ccagtaaatg aatcttctta cgcagattct caaaagaatg
    35581 ttcctgtaag ccaaaatact aaattgactc aagagcaagc taaagaactt ttagtaaaat
    35641 acaacaatga agttgattac atatatcaag gaaatgctag tgattttgaa gcattaaaag
    35701 ctaaaaatct taatggttat gtatttttac cagatgcaga tggcgatatt ggttactttg
    35761 taaatgaaaa tacttctgag atatattact tccacccaag tggatatctt gaattagtta
    35821 atcaacaaca aaataataaa taactaataa aaaatggatg caaattgata taaatttagc
    35881 atccattttc tttttatttt aaagttgttt ctttttatag aatttaaata ctgttttaat
    35941 cctgtgcttg ttcttttata agtttcttta tatctacagc aggttcatct tccattttta
    36001 taacttttcc ttcccatgtt ctaagcataa cataatctgt tccttttgat acaaggtatt
    36061 gtggaagcaa aggagttttt cctcctcctt ttggagcatt tactatatat gttggtatag
    36121 ccattcctga tgtatatcct cttaaatact ccatgatttc aagaccatca tctactgatg
    36181 tattgaaatg ttttgttccc tttacatgtt tactttggaa tatataataa ggttttactc
    36241 ttatttttag taattcttga tttaaacatc tcattacaaa tttatcatta tttattccat
    36301 ttaataatac tgcctgattt cctaatggaa ctcctgcatt tgctaacttt tcacaagctt
    36361 ctttagactc cttagttatt tccattggat gattaaaatg agtgtttata tatataggat
    36421 gatatttttt tagcatattg caaaattcat ctgtaattct ttgtggcatt gtaacaagag
    36481 ttctagtacc taatctaaca taatcaacat gcggtatctc tttaagttgg ctaagaatcc
    36541 actctaaata atcatctttt aatgtaagag catctcctcc agttactagt acatctctta
    36601 tttcttcatt ttctctgata taatctatag attcttggat aatagctttt gacttatgag
    36661 aatcttgttg tccaatattt cttcttcttt gacagtgtct acaatacata gcacactcat
    36721 ttgttacatt tattattaat ctatctgggt atcttctagt tatacatcct gctggatttg
    36781 tatactcttc tcccattggg tccaaatctt cttgctcatc ttctaactct atatatgttg
    36841 gtatagacaa taattttatt gggtcacata tatcttctgg gtctataagg cttaaataat
    36901 atggagatat tgcccatcta aattgagtac caacctcttt tatatgttct ttttcttttt
    36961 tagttagagt tataatcttt gataaagtat ctacatctgt tattctattt gataattgcc
    37021 atttgtagtt gttccaatcc tcttcagttc catttaatat actcaatatt ttctgttttc
    37081 gtttatttat ctcttcttct ttttcaagac ctctgttaat cgtttttcta gcctgaatat
    37141 aatcatcaat ttttgatttt agttcagcag ctctctctaa ggatattcta gtttgttcat
    37201 tcataatttt ttgctatcaa agttaactac ttatattgtt tgatagcctc ctcctttctg
    37261 atgtgtttat atcattctga taggcaaatt tgattttgcc atatagattt tataacaaat
    37321 gaaattgaac ttatttttgc attttttcta ttattttgca catttatgaa tatttttcta
    37381 ctttcgtcaa taaattacaa catattatgc atttttttta acaaatgatt aattttttct
    37441 atttttaaga attattttat cataaaacga ttattttttc aagattatta aaattaaatt
    37501 tttaatagaa agtaaagtat ttcattaaat aataaaagcg gaggtttatt ataataaatt
    37561 tctccgcctt tttatttatt taattaaatc atagtaaaat aaatttagct attaagaagt
    37621 gactttatta tattgagccc tttttctaat tcttctacat cttttggagc tgttatgcaa
    37681 atacggattg cttttggtac tgtagagttg cctactgaaa atcgttctgc acaatacact
    37741 tgaacaccta gattttttgc agatatttca aatgactttc cctccaattc atcaaattat
    37801 aatctgacaa aactttatca gcaactttat ttccttctat aattgtatct tttttctctt
    37861 ttataatctt atctaaaata ggagaatata gtaaacggtg tactatttct gccgtaaatg
    37921 gagaaaccat tagattcata ttatatagtg catcttctaa gttttctata tatcgttttg
    37981 gggcaactac aaatgctatt ctaagaccag cacataaaaa cttagatgta caaaaaatat
    38041 atatagtatt atcactggcc aaagaaaaca taggagtttg tgtactatct ctaaaaatac
    38101 tgtttatggc atcttcaatg attattatat ttattgtttt gctatctttt tacaagataa
    38161 atcagacata gaatgtgtcg ttggattatg ataatctggt ataagatata tgccttttat
    38221 attttcattt ttacaataac tttcaagatg ttcaatcgac atttcattat tatcttgagg
    38281 aattggaacc aattgaatac ctattatttt agctattgat ttaattccag aaaactcaaa
    38341 gaatctgtag caatcctatc acccgcttta aataatccta gtaaggttgc acatatagca
    38401 ttttgccctc ctgtagataa taagatattt tcttcactag tgtatatatt atttctctct
    38461 atccattttg caattgattt tttttgcatg tacgtaccag atggagacat atattgtaaa
    38521 aatttatcta tttctggttg atttagtata cttttaataa aatcaataat atatgtattt
    38581 tgctcatatg gaggatgaac tgttcctagt tcaattatgt cttttgattc tgtttgatat
    38641 aataatgtat tacttacatt tacatcaaag gaaaaagaaa taaaaaaagt agctttatta
    38701 ggtactaaat atacaatgga acaagatttt tataaaaaca taattattaa taatggaatt
    38761 gatgttttaa ttccagatga agaagaccgt ataatagtaa ataatacaat atttaatgaa
    38821 ctttgtgttg gaattgtatc tgaatcttca aagaaagctt tcttatctat tatagataag
    38881 cttggcaagc aaggtgcaga gggtgttata ttaggttgta cagaaacagg tcttttaatt
    38941 aaacaaaatg atacttctat tccactattt gatacaacaa taatacatgc aatagaagca
    39001 gcactaagtt caatttaata caatatcaat taataaaaaa atttttttaa ctaaaaattt
    39061 gaaacctcta tattttaaca aaaaaggata gtatgattgc tatcacacta tcctttttct
    39121 taatttaatt tttcaataaa cttaatactc atttgtatac aaatctatct tacatttata
    39181 acatcactat tttgagagtt attcccatta taatttgcaa caacataaat atctagattt
    39241 aagtctcctt caggaatact tatagtatgc tcattcccct gtatatcact ttgatataga
    39301 gtaaattctc catctccatt agtattattt tttacatata tgctgtaagt acaatcctta
    39361 tgagatatac tactccagtt gactctaata acattattat ctctatcaac attagctgat
    39421 atactttcta ctttcatgtc tttaatgtta ttatcattat ttgaatttcc attcccatta
    39481 gtaatattta ttacattact tggcttagtt gtatctgaat cctttttccc tatgacatag
    39541 atatcaaaat ctacgttttg attccccttc atatctactt ctatagttgc atatactttg
    39601 ttagacttac ctaaatcact ttcatttata gttatagatt taattttctt aaatgattct
    39661 cctgacaatt tatctttaag atatatatca taatcaaaga catctttcat ataatcccat
    39721 tcaagtttaa taataacttt attatttact attttatgtg agccaaccaa attttgtata
    39781 tagtcattcg ttatagtttc tttgactact gttactgtta ttattttaga tttatctcca
    39841 caagttattc ttaccctatc tttgccttct ctaagcccta caatatttcc attactactt
    39901 aaacttattg ctctttctat aggtaatttt gaatctacta actcataata tatttttggt
    39961 ggttctaaac caggtggaga agttattata tctggtttca atttttcatt ttggtcaact
    40021 tctattttta tatcatccat atttatttca gcaactctag cttcaatcct aaatgttctc
    40081 tcaacttctt tatttccaca cttagcatat attgtagcct ttccaactcc aactgcactt
    40141 actctatttc ctttgatttt taaaatattt tcattactac tcttataaac tggcttatat
    40201 gattttttaa acttgtcata atcaacctct attgtgcttt ctatagtagc actatcacca
    40261 acatgtttta aatctccatt aatctccata tctagtgact ctacctctgg gtctactact
    40321 tttatagtag ccttttttaa tactcttgaa tttttcatga tacccacaga agaataccca
    40381 acctttaatg ctgtcatttt atttccatct atttttaaag ttcctgaatt atccaataca
    40441 ttaaaccaaa tatttggatc tttagcatac gaaggaacct taatatattc accagtggat
    40501 aaagtaactg tttcatttaa ttttactaca tacttatcta tatctttaac atattcccca
    40561 tctacaattt caatttctac tccctttacc attggtctaa gtattccaaa tttaaaaagg
    40621 tagtactgcg caacaagcaa tataggaata gatataatta tagcaatttt tctgtatttc
    40681 ttatttttta taaatctcat ctatccactt ccttttagct taatatataa tcatttgttt
    40741 tgtaagcaat ctacctaagt taaatattgg gataaactgg aaaattatta tatttcagaa
    40801 tatccctata ctaattataa accataaatt taaaatttaa aactaaaatt aatgttaatt
    40861 tcttactatt gcaatagtct aattttagtg aaataacatt tgtcttgtca gctgaaaagt
    40921 tatataatta attaaaaaga aattatactt atattatatg aggaggattt taaattggaa
    40981 atcaattata aaaaaagaaa tttcaaatca tttgctaaaa gaaaaaacat tgaaatttct
    41041 gttcaaaggt atcttattga tgcactaagt tatatggcac tcggtctttt ttcttccctt
    41101 ttaattggaa caatttttaa tacattagga gataatttca atatttctct ttttactgag
    41161 gttataagcc ctcttgctaa acaggttacc ggtccagcta tagcagtggc tattgcatat
    41221 ggacttcaag cacccccact tgtactattt tcttgtgcac ttgttggagc ttgtggtaat
    41281 gaattaggag gacctgttgg agcatttgtt gctacacttt ttgctgtaga gattggaaaa
    41341 ttagtttcaa aagaaacaaa aatagatata ctggttacac ctgctgtaac aatactaatt
    41401 ggagtacttg tagctgagct tattggtcca gctgtttctg cttttatgac ttcatttgga
    41461 aatataataa tgcaagctac aactatgcaa cctataataa tgggagcttt agtctctgca
    41521 cttgtcggaa tagctcttac attacctata agtagtgcag ctatttgtat gatgttaagt
    41581 ttgggtggtc ttgctggtgg ggcagcaact gtaggttgtt gttgtcaaat gataggcttt
    41641 gctgttatga gctttagaga aaatggagtt ggtggccttg tggcacaagg tcttggtaca
    41701 tctatgttac aagtacctaa tataataaaa aattggaaaa tttggatacc acctactgta
    41761 gcttcaatat tacttggacc attatctaca acaatattca aaatggagaa tattcctatc
    41821 ggctctggta tgggtacttg tggattggtt ggacaatttg gaacagtgac tgctatgcaa
    41881 agtgttggaa agggaggtac atctatgtgg gttggtatac ttttacttaa ttttatactt
    41941 cctgctattg taactttgtt gatttcagaa tttatgagaa aaaaaggtct aataaaacct
    42001 gaagatttaa aactagatgt gtaaattaaa aactactcct tttacttata taaaagtaag
    42061 gagtagtttt ttttatgaaa attccaacat tttttttaat agccaatcca tagaaccttt
    42121 aacttcattc caaatcacta tgttttcatc atagtaatat acagcttctg ccttttcttc
    42181 ttctgtaaca aattctctac caaaagcatt tcgccaatct aacaaatata atccaacata
    42241 cttattttta cctctagcaa ccttaataga atcatttgcc aaaaacatac ttttattttt
    42301 aaagtaataa agagctttac tgtacatcca tgtagcagat ttttcttctt tataaagttc
    42361 aaataattta tttattgagg ttctatcgtt taatctaatt aatacattta ataatttata
    42421 tcttattccc tgctcatcac taggattaat ttctattaaa tattccaata cttttttgga
    42481 ttcatttaga ttattaatac tttctaactt cctagcaagg gattcaagtg ctatcatata
    42541 ggctctggta gataaacctt tccaaaatcc aagttcttta tcttctttag taatcatact
    42601 tttacctata tttacagctt cctccatata tctaattgat tcaatatcac tatttgcatc
    42661 ttgtgatagc ttaatatatc ttttatatag tattttcttc ttttctaaat ctaaatctac
    42721 agactttgat ttggaattta tctcttttac ccaaaattct acattagaaa tagctatagt
    42781 atcttgattt aaaaagtcaa tactacaaac atcctttatt aaagatgatt tattatttat
    42841 agtatttaaa gaaacaccta tttgttttga aaactctttt tttgttatat gtagtggatg
    42901 cttcttattg tataaaagat tttgttctaa aactatattt agtatagctg aagaccatat
    42961 atcagctcta gaagaatgaa ttatctcttt attattatct aaaaggtttt gcaaaatttt
    43021 aaagcttata tccttgtatt cttgatttaa attggagttg caaaatctat ttatcttgtc
    43081 cttaatttct tctatcttgc ctgtcatgac tcctcctcca tattttacat atataaaact
    43141 agtgctacaa actcaagatc ttcttctcct atattttcta tagaatgctt ttcgccatca
    43201 gctgtataca ctacatcacc ctcatttact tctacaaatt ccccattatc aaatactttg
    43261 ccttttccct ttagtatata atatacttca aaatctgttg tgtggtcatg cacaccaatt
    43321 gaacttccta ctggtaaaga taccctttta aatagtcttc cttttccttt aagctcttca
    43381 ttttgtatta tgttttcaag cttaacattt cctataccac catttaaatt ttcttttact
    43441 tctacttgta attcagattt ctttcttatc atagctcatc ccacctgcca aacaatcaat
    43501 ctaactacta aattggcata tcctttccat aaatatgttt gtattttaat ataataataa
    43561 catatattat cataaaaaaa tattattgaa tacacaaaaa tgatactatt tttacatata
    43621 tttcgactta attaaattat ctcataagtt gacgtctcta tgaaaaaaac atatactcat
    43681 atagtatggt aaaattttgt taaactattt atctggaggt tctcgacata tgtcagtttt
    43741 aaaaacgcaa gaaaaactta aacaacctaa agatttatat ttctgctgtt caatatttac
    43801 ctttgtagga cttgcatact atggcatgaa attggtatta ttattatttt tagctgaaca
    43861 agtctccaaa ggtggtttag ggttaacacc agcagaatcc gcatcaatgc ttgcatcttt
    43921 tttatcatgg acttatttct ctccagttat cggtggatgg gtcagtgata gatttctagg
    43981 tcccaaaaac tgtatcatac ttggaatgct aatggtttca attggttatt ttctaggata
    44041 catagcaaat agtaagatgg atataaacat catgatattt ttatctggat taggaatagg
    44101 tttttataaa ggaaacttac ataccatggt tggaaactta tataccaatg atgacccaag
    44161 aaaagatgga gctttctcta ttacatatat ggctactaat ctaggtactt tatttggtcc
    44221 tttaatatgt ggtttagttg ctaatgaatg gtttgctatg aaaagtggag cctctataag
    44281 tatgtatgga tacagatatg tattcttatt ttcatcaatt acggttctaa taggtttatt
    44341 cttctttgta tttggaaaca gaaagtttta taattcttta aataataacc atagtaatga
    44401 gagagaatct ataagaaaat cactagaata taagaaaatg ctcgcttcaa gaccattaac
    44461 tttgattgag aaaaaaagaa taatagtaat attggtatta gcttttttca cagtattttt
    44521 ttggatagca tataaccaag cctctatgtc tattgcactc tatacaaaag agcatataaa
    44581 tcttactgtt ggcaattttc aaattcctac ttcatggata gattcatata atggtctcct
    44641 ttgtgttatt cttggaccta tctctgctct agtatgggta aaattatctc aaactaaaaa
    44701 aggcgattta agtgtaccca aaaaaatgag cttaggtttt atactattag ctatagcatt
    44761 tttatttatg atagtagcag ttatgcaaac aggtacggac tctaattcaa ttcataaagc
    44821 aagtgtattt tgggtagttg ggtttttaac attccaaagt ataggagaaa tttgcttttc
    44881 tccagtcgga tatggtatgg taaataaact ttcgcctgaa aagtatattt cattactaat
    44941 gggtgtttgg tttttaggta aatttgcagc aaataaatta tctggttata ctcaagctat
    45001 tatagaccaa cttggtatgt tacaagtatt catagtgata ccatcatttt tattgatatt
    45061 tggaattata ctacttataa tgaataaaaa gttagtagaa ttatcaagtt aaaaattttt
    45121 caaaattaat aaaagataca ataaaaaatc gaggtattat aatacctcga ttt
//
LOCUS       DAMKOJ010000245        22568 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.059, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000245 DAMKOJ010000000
VERSION     DAMKOJ010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22568
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.059"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            278..1210
                     /gene="blaCDD"
                     /locus_tag="PC592_003757"
     CDS             278..1210
                     /gene="blaCDD"
                     /locus_tag="PC592_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF4057640.1"
                     /translation="MKRKKNFIWTTILLVGIVMVMYYAGKKHNDINQKTDKNYIKSDL
                     NKSEINNDNNKKERVNIVNYSDCFEGISGGAIFYNSRNQEYNIYNKDLIETRASPCST
                     FKIISTLIGLEKGVITSKKSVIGYDGTNYPNKNWNKNLSLEEAFKESCVWYYKKLINK
                     VDAKSVQSILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMVKIF
                     EGDTNFKKEHINILKDIMKIDVSDKNINVYGKTGTGFNGKNKRVDAWFVGMLESKDDT
                     YYFAIKSDDSNKEIAGPKVKEIAINIIKKYYSVM"
     gene            1559..2242
                     /locus_tag="PC592_003758"
     CDS             1559..2242
                     /locus_tag="PC592_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057641.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHMLGGVDRPTSGKIYVEDTEISSLNEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     TILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2239..4899
                     /locus_tag="PC592_003759"
     CDS             2239..4899
                     /locus_tag="PC592_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057642.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDDTYGKDLSLIENFSSVDDVMVKGQWYVGKINNDKRDYI
                     VYRNATSEYWNHMPEKDSIIEGRRPSNTNEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPVAPKSKGESFKKISKTTLTIVGKVDVATSSVVPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SNISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNKLIVYINSVNYHTDAPEVVFTYGIPAFLPAVLL
                     TIVTVWISTLIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTGFLHIIANQEGAEAVYGSDNYKDQRDIEVYLENSEPVE
                     SDFIEKLDNTEGVKNSLYYQKMSATTWLTEKDASKELSKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDESFAEYCRQISVDPKLFYDTKNPTSIVYNKEEDVNRSTRRNKVY
                     IDYLNLSIGDNIKLNEKIYDEDKGDYTYNMKVGAITSTLPKIIDTSSRYTLMQIVPIS
                     MVQEISKNYAEVGRSRSNRLIGLFKVDNREDIPRVRGKLESICNKDYGSGDYSIEDVV
                     ENEKQNGSGRKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPD
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYTFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYNQLKNENIVESIKSETI"
     gene            complement(5076..6257)
                     /locus_tag="PC592_003760"
     CDS             complement(5076..6257)
                     /locus_tag="PC592_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4057643.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKVL
                     DASYEYNPKSTESILKSLKNSSDEDFKTGNEILSKHGYSKGTFWSKNFFYFLVVSFGI
                     ISTMAIVVYIIKYRTNKQKLSRINMLTRYLEEVNLGKESVLLRYEDEFSYLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TKQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     KGSPSIEFEIDINWTLEALLNILKNCSEHIEAGGHIIAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6257..6919)
                     /locus_tag="PC592_003761"
     CDS             complement(6257..6919)
                     /locus_tag="PC592_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4057644.1"
                     /translation="MAKILLLEDDDTITFGIKTSLENKNHIVCCYNTIAEAKKNFDKT
                     TDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRAHSNTNNTITCGNISLNKVEVKAYLDSVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7035..7673)
                     /locus_tag="PC592_003762"
     CDS             complement(7035..7673)
                     /locus_tag="PC592_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF4057645.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFSLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSKKSDTEMLFKEKFFSFNKFMFDEIQEMFEIGKNDGSIRYDI
                     EISTLMYSSIFTLTGFFNLLSVTRKSYLNNFNIDEEKFIETTLAILIDSIKA"
     gene            7853..8458
                     /locus_tag="PC592_003763"
     CDS             7853..8458
                     /locus_tag="PC592_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF4057646.1"
                     /translation="MKIKENVLRLDSTRGSNCFIVFDKEITLIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHMSNIKLLKEKTGAKVWAHTEDIPFIIGEKDRPGFKK
                     FIGKTISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVSYPNPWNWDSKKMMKSIRELDNLEYEWICMSHGTPCIK"
     gene            8559..9281
                     /locus_tag="PC592_003764"
     CDS             8559..9281
                     /locus_tag="PC592_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF4057647.1"
                     /translation="MIRTLILYYLNIKPTHGYEIQKFLQVSGADRWTKIQSGSIYYAL
                     AKLEKDGGVRVLKEEKTGARIRKIYEITQSGKLELREEIQKELQMPIVPTGSNKFLLH
                     NILDVLPKDTLQKNLEKHIKYLIEQKKYWENWKEIKKIDKKSLATEKIAFDMTIDNLN
                     YQILWHEEILNDIDKYISVGCETQNIIKSIDFSNIEEDFLFTSDTTNELLEVQRLRDE
                     IINNPDKAIENIDKIILKLQNK"
     gene            9383..10141
                     /locus_tag="PC592_003765"
     CDS             9383..10141
                     /locus_tag="PC592_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057648.1"
                     /translation="MSNILLEIKNLSKKYNNKEVVSIESFKLLEGDILGFIGANGAGK
                     STSINMLTTIVSPDSGSIYYKGKDIKNQQNIFKSSLGVVPQELAIYEDLSAYDNVKFF
                     CSLYGFKGNELKERTKDALEFVGLWESHKEFPSKFSGGMKRRLNIACAIAHSPKILIM
                     DEPTVGIDPQSRNKILEAIKCINTNGTTVIYTSHYMEEIETLCNRIALIDKGIIIEDL
                     DKSLYKNKYLEFGCKTLEDIFLYLTGTDLRDLEE"
     gene            10146..10886
                     /locus_tag="PC592_003766"
     CDS             10146..10886
                     /locus_tag="PC592_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057649.1"
                     /translation="MRCFLPLFKLGIKRRSKDFFILFYNIVFPVIIIMLLGYLTSKSY
                     GEEFTSYNYYTIVTIPFCVLMGIISVSYAGQDEKISNTSYRYMISPISIVDLVISKLF
                     SCTAVLSICNLVTLVVLKCIFRMSFGGKFLAVLFFLMCESIVVVSMGLFLGLVCKNLD
                     MLRNIINIPIVIFGFLGGVFFPVSSLNPVISLIINISPLTWINRGIVACIYDNNLQLL
                     FNISCIFVVVSIFMTILTIKFFKKGVFI"
     gene            10886..11938
                     /locus_tag="PC592_003767"
     CDS             10886..11938
                     /locus_tag="PC592_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057650.1"
                     /translation="MNVINVFNINLKRNINKRIVFLVTLLFPIIIVILGVLANYISKP
                     FFNIGILDEYKNERVLKESEKRTYENTIMALENTQGINTKIADFKTIKTDIITGKYSA
                     VIYFNKNGFKLYSIKNKNTNDTLKYLIETYKKDPVPVDISKLQENTLGVLQRIIAFIV
                     LFLMITSTVTASMIIKDKNSGTFTRVLYSPQNVRGYVLGNMLYNFTITYFQYIVSISI
                     IKLFNIDIGMDYIDLILMGIWVVALATSFGTFVSSLFNREMHANLFSTCISLVLSLIG
                     GSFISVEKMPEMLQKISIISPVRWFISFVTYIEERDGSFFNMNYICILTSIIIVLALL
                     AMKFTQRSKYSSNSNY"
     gene            12340..12906
                     /locus_tag="PC592_003768"
     CDS             12340..12906
                     /locus_tag="PC592_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057651.1"
                     /translation="MNNLFYDKLNFDDKLIIKNNGVIRNNDLYFLKYKNDTAGILIYN
                     IINDKFSFKQNKNYKGMNPFPITNIFKNLDSDKWDEFIRIWIEERVIQECRPEVPFIL
                     KEFKLGYYDVWDICRSNLAMSVEDFFWITKDNTLRYEDFNIRYCTLNNITPIYKPPFP
                     IVIYPNYFEREKIKSGETWKYELKNTNS"
     gene            13402..15615
                     /locus_tag="PC592_003769"
     CDS             13402..15615
                     /locus_tag="PC592_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF4057652.1"
                     /translation="MNQSYHNIKNELLSKQLAYIDRLTGYLVDRDNYLSGYVKEKLKI
                     AKEASIKDNTFLVNVKALEANQPKYETDVFFSIDSTWISSSIKSDFIEKTLELKENSI
                     QLLYSTQLGYSVKCSDIIPISKNEFTWGTKRRKSLYIVEAELNMKTITVTDKEYQNGK
                     EVSVKNLEETQLAMNILNKWLIAFHNYVTSNSYIHKELLDRYNEMFIDYKEKEYKNIL
                     NDVRINPNIKLREHQLKAASRIITSDRNTLLCHSVGSGKTYTMITAAQELNRISKIDS
                     KKGNKNLFVIPNSLCESGQFAKEYFNLYPQANILATTSKDFSKSNRRKIIAKIVTCNW
                     DSIIIPHSVLGLIPLEADTELKLLDLYLKELNDTLKYYKKECPDLSTKRLETMKENYL
                     NRIKELNDMHKDDALLSFEKLGITNLFIDEAHNFKNLYFNTTMQVPGISTLKTKKTQD
                     LYNKLRYFKSIHGNKGVTFATATPISNSICEMYTLLTYLNKDTLKYYKVDTFNAWASK
                     FGSIISSMEVDPTGQGFRFQQRFAKFCNVPELVNIFRQIADVVNICDINDLDIPQIKG
                     GKPIIEIIKPTNQMKEYIDSLVKRAEKIHEGPYDPIIDNMLNVTTDGRLMAVSPALVG
                     IDGILPKIIKVGENIASLYHEDKISTHLVFCDLGTPNGNSHNVYNDIKNELLKNNVLE
                     KDIAYIHDANTPEKRKKLIDDFNNGIIRILIGSTSKITSSCRCSLETFINFTKRR"
     gene            15788..16018
                     /locus_tag="PC592_003770"
     CDS             15788..16018
                     /locus_tag="PC592_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF4057653.1"
                     /translation="MSYAETKACACSDDSILKLCEINREIQIIEINKKAFLNQNLLTL
                     NDIKSTENSIDALKISISKLEEDIKTYFSNFF"
     gene            16134..16490
                     /locus_tag="PC592_003771"
     CDS             16134..16490
                     /locus_tag="PC592_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HDF4057654.1"
                     /translation="MNIIYEKEFTFDNKVREFISLGNNYKFEFSTSKSPKTLIKYFMD
                     YNKISSNKLESFKEKYSFKKNELLSLQEILKNKFTEDDKLESLKLSKANLENELKLGN
                     SIIKKSNSNHNMVEKK"
     gene            complement(17435..18247)
                     /locus_tag="PC592_003772"
     CDS             complement(17435..18247)
                     /locus_tag="PC592_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8/S53 family peptidase"
                     /protein_id="HDF4057655.1"
                     /translation="MNYSDMHEISSGKSQKIALIDSGISKFQKVYKNINLTNSNNDYD
                     TNGHGTMMYSIIKGYNKNNQTIEGISPDSRIILIKVMNDDESINPNVIEDAIDYALNE
                     KVDIISLSLGSTKTDINIKQKIDKANLKNITVVSSAGDYKQGFLLFPASLNNVISVGS
                     IDDRRDISTLTNAPQKTLINAPGEKIKVIDNNNNVFYGKGTSEATAIITGYIALMRDT
                     NISSTQILTNEKIMNLLSQINKNEKTYLGALKEIRKKVSVSTGAFFSFDLSY"
     gene            complement(18395..19081)
                     /locus_tag="PC592_003773"
     CDS             complement(18395..19081)
                     /locus_tag="PC592_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057656.1"
                     /translation="MKYFKKVIALGLSIALLIPVISINALEKKDTNVNNQIINVIESN
                     VSYTKEGIEVSSDLKNDLKEINLEDIKEQMIEQGIDSKFINNFNSDVIYSLVKENIDD
                     INEGVKNKTLKITPEEDIINNTDNSFYVQGGSTYTQKFSWGVRQNKSTAAANRWVYDL
                     NKSSQGFVATGAVSVLLGSMGAPIGFVSGLSAAYMGGLANKVSYVNSRNNRGITVDIN
                     WWLTYAVKNQ"
     gene            complement(19111..19533)
                     /locus_tag="PC592_003774"
     CDS             complement(19111..19533)
                     /locus_tag="PC592_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057657.1"
                     /translation="MYLKKVIVAGLCTLTCLLPLNVQAFEDTSLNTNDYNQTNDNDLF
                     MIYIKGAGSNLSIRSGKAHISCYVDGKIGSLTSITARLQQKKSGKWVTISTWSSSGKT
                     SSTLSREYRVSKGYSYRILTTIKAGNESRNITSNVTNY"
     gene            complement(19608..20066)
                     /locus_tag="PC592_003775"
     CDS             complement(19608..20066)
                     /locus_tag="PC592_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HDF4057658.1"
                     /translation="MSVDTLRNQFIKIVIEIYEDLTEFIFSKDIQTDKNLDFILKEPK
                     YIPNGFKEVEKENTLQGIFIRYENKNGSEIRYRSNQIDSNTVILDTENAKVTDIMVND
                     YEAKYIVKDNSITIFWNDEENVYTIYFDYDNKNDLNKYKDNLIDIAENIK"
     gene            20259..20909
                     /locus_tag="PC592_003776"
     CDS             20259..20909
                     /locus_tag="PC592_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057659.1"
                     /translation="MEVIRNMTNVSSLEKEDEIVEILSSKENIRVAIEIERGLKLCKT
                     QMIKKVLEEIEKRMDKKFEDKYKLPYYSYKENNYALVNNYYNKKSSTYPAINYFIKSL
                     DKEDVDLLLRIEIDHHIFVGFCTLYKEKPSGKILSDDEIKELINDDGSRTNGWWICWE
                     YIYNNTMECPNFKNFNDAYFDLFDDNKFDEFMDLCEKRILSILGKLKDKQCINTFI"
     gene            21060..22091
                     /locus_tag="PC592_003777"
     CDS             21060..22091
                     /locus_tag="PC592_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057660.1"
                     /translation="MKIEMGESLLYSWLRHVKECQIVQTNWKVSSKWDLKNADKILEI
                     MEKTKQYFEQKYGYPIYKNNSLEQLIMQAEVDVLGISIDNGRNHIYAIDVAFHEAGLN
                     YGSKNETVTRVIKKCIRTAMCIYGYMDLDEAEIIFASPKINPAIITELEPKMAEVNDL
                     FKSLGLRFKTRLIANEEFNGKILEPILIASDGISDTSELFLRSYQMYSMFSYSRDVVK
                     QQRIKKSNSLKDAVELNLSDETLKELKIGKLVQVTMKHLFEEEKISPEEIDKMTQSSY
                     SKQVFNENKPVLKEVPKDGNINELKKDEKNYNRYYAYTISIYGKQYLLVSQWIEDLHR
                     SYYESWVIK"
BASE COUNT         8682 a         2677 c         3222 g         7987 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaaagt agaatcaaat actatatcac
       61 aaattaaaag gaggacaaaa tgctattaat agttacctaa ttattttcgt aataggttta
      121 atcgacatag ttgtgctagg tgaagaaaat ataagatata tagttattcc tttagtctta
      181 ttttttataa gtagcaccta gattgaagta tattacaaat aatgtctact attttaaaag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggacaact atcttgttgg ttggtatagt tatggtaatg tattatgcag gtaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttacataaaa tctgatttaa ataaatctga
      421 aattaataat gataacaata aaaaagaaag agttaatata gttaactata gtgattgttt
      481 tgaaggtatt agtggaggag ctatttttta taatagcaga aatcaagaat ataatatata
      541 taacaaagat ttaattgaaa caagagcttc accttgttct acttttaaaa taatttcaac
      601 attaattggt ttagaaaaag gggtaataac gtcaaaaaaa tcagttattg ggtatgatgg
      661 tacaaattat ccaaataaaa attggaataa aaatcttagt ttagaagagg catttaagga
      721 gtcttgtgtt tggtactaca aaaaattgat aaataaggtt gatgctaaat ctgtccaaag
      781 tattttagat gatttaaagt atgggaactg tgatattagt gaatgggaag gagatttaaa
      841 aaatggaaag gggcatttaa atggattttg gttagaatct tcattacaaa tatctccaaa
      901 agaacaagtg caaacaatgg tgaaaatatt tgagggagat acaaacttta aaaaagaaca
      961 tattaatatt ttaaaagata ttatgaaaat agatgtaagt gataaaaata taaatgtata
     1021 tggaaaaact ggaacaggat ttaatggaaa aaataaacgt gtagatgcat ggtttgttgg
     1081 tatgctagag agtaaagatg acacttatta ttttgctatt aaatcagatg attccaataa
     1141 agaaattgca ggaccaaagg taaaggaaat tgcaattaat ataattaaga aatattatag
     1201 tgtaatgtaa taaacttaat tttatttgta aatattggtt acctatagtc tgtaaatatt
     1261 tattaaataa ttttactaaa ttgagtttac atagagcaaa actcctctag tatataaaat
     1321 acttgctatt gattattaaa ttgaatactt atagatatta aagttaatat cttttaaagg
     1381 ctatgcaata tattaaaagt ataaataaaa tatattgcat agtttttgtt ttgtattata
     1441 attttaaata atgttcaaaa actaaacaat atttttaata gtaatcgata tttgtattca
     1501 tgtcactata atgtcatttt aggttgctaa aatttaacca taaaggagat gagtgtatat
     1561 ggaaatatta aaatgtgaaa atctcacaaa aatatatggt tcaaatcaaa ccagagtgac
     1621 agctcttaat aatgtaaatt tatcagttca aaaaggtgat tttgtatcca ttgtaggagc
     1681 atctggttct ggcaaatcta cattgctaca tatgcttggg ggagtagata gacctacatc
     1741 tggaaagatt tatgttgaag atacagaaat atcaagctta aatgaagaag ctcttgcagt
     1801 ttttagacgt agaaaagtag gtcttattta tcaattttat aatcttatac ctactcttga
     1861 tgttagaaaa aatatattat tacccatgtt acttgataaa agaaaggtgg atgaagatag
     1921 attctctgag attgtatcta tattaggatt atctgataga ttgaatcatc ttccaagtca
     1981 actttcaggt gggcaacaac aaagggtatc tatagctaga agtttaatct atagaccaac
     2041 tattttatta gcagatgagc caactggtaa tctcgataga aaaaattcag aagaaattgt
     2101 agatttgtta aacttatcaa ataaacgatt taatcagaca atacttctta ttactcatga
     2161 tgagaaaata gcactagagg caaatcgtat tgtaactatg gaagatggag tgattgtctc
     2221 tgaaaaggtg gtgaagaaat gaatattctt caagaatata ccttagactt tgtacgacgc
     2281 aataaacgta gtagtatagc tataatgtta gccatattac ttaccacaac catgatgtct
     2341 tccttgtgtg gattgttgta taccatgtgg acagatttta taagactttc aattgagaaa
     2401 gagggtaact ggcatggtga attgtttgac gatacttatg gaaaagactt atcgttaatt
     2461 gaaaattttt cttcagttga tgatgtaatg gtaaaaggac aatggtatgt aggcaaaatt
     2521 aataatgaca aaagagatta tatagtttat agaaatgcta catcagagta ttggaatcat
     2581 atgccagaaa aagattctat aatagagggg cgtcgaccaa gtaatactaa tgaaattgca
     2641 ctatcaaaac aatattttga gaataatcca agtgtaaaaa ttggtgataa aattactctc
     2701 ccaataggag atagaatcct aaatggaaag cctcttgaac ctgtagcccc aaaatcgaaa
     2761 ggggaaagtt ttaaaaaaat ttcaaagact acattgacaa tagtaggaaa ggtagatgtt
     2821 gctacttcat cagttgtacc tgcatataca gctcttggat atcttgataa aacaagtata
     2881 aaacctaatg acagtataac tgtgtacttg cgatttaaaa atataagaga cacatataag
     2941 gaacttccaa aacttgctaa atcattggga tggaagacta atgaatatgg aaaatacaat
     3001 cttaaataca atagtaatta tcttttaaaa atgttagtct tttctccaga acagaaagca
     3061 tctatgagca atatatcaaa attttcaact cctattatgt atcttacaat agcaattttt
     3121 acagtagccg tgtttgtaat ggtaatttac aacgcatttt cactatctgc aaatgctaga
     3181 cttacacaat taggaatatt atctagtgtt ggagcatcac caaaacagat taaaaggtct
     3241 gtagtgtttg aaggtttttt attgactatt ataccattac caataggttt atttttaggg
     3301 tggttattgt gtaataagct tatagtctat attaattcag ttaattatca tactgatgct
     3361 ccagaagtag tattcactta tggtattcct gcttttctgc cagcagtttt acttacaata
     3421 gtaacagtct ggatttctac actcatacca gcacgaaaag tatcaaaaat atctcctata
     3481 gaagcaatac gacaaggaga tagtgttaaa attaaaaagt cacataaata ttcattagga
     3541 aagatatttg gaatagaagg agaacttgca tcaaatgcac tacgtgctcg taaaaaatct
     3601 tatcgtactg caacaatatc tttaacatta tcttttttat tactgacagg ttttttgcat
     3661 ataattgcaa atcaagaagg agcagaagct gtttatggaa gtgataatta taaagaccaa
     3721 agagatatag aagtttattt ggaaaatagt gaacctgtag agtctgattt cattgaaaaa
     3781 ttagataata cagaaggtgt aaagaactca ctatattatc aaaagatgtc tgctaccact
     3841 tggctgactg aaaaagatgc ttcaaaagaa ctttcgaaaa atggaggatt taaaagtata
     3901 gtttcatcta aaaagtactc tcctatagag cgtgatggca agtttcgtat aatttcaaat
     3961 ataattgggc ttgatgatga gagtttcgca gaatattgca gacaaatctc tgtagaccca
     4021 aaattatttt atgatacaaa aaatccaact tcaattgtat ataataagga ggaagatgtt
     4081 aatcgtagca cacgtagaaa taaagtatat atagattatt taaatctttc aataggagat
     4141 aacattaaat taaatgaaaa aatatatgat gaagataaag gggattatac ttacaacatg
     4201 aaagtgggag ctattacaag cacacttcct aaaataatag atactagttc aagatataca
     4261 ttaatgcaaa tagtaccaat atctatggtg caagaaatat ctaaaaatta tgctgaagta
     4321 ggtaggtcac gttcaaatag actgatagga ttgtttaaag tagataatcg tgaggatatt
     4381 cctagagtaa gaggaaaatt agagtctatt tgtaataaag attatggttc aggagactat
     4441 agtattgagg atgttgtaga aaatgaaaaa caaaatggta gtggaagaaa gactatgaat
     4501 ttgatagtag gttttattac aggtttattg gctatgattg gattatcaaa tgtacttgct
     4561 acagtgtcag gaaatattag aagtagacga caagagtttg ctatgttgcg ttctgttgga
     4621 ttatctccag atggcataaa aaagatgctt gttttggaag gtttattctt aggaattaca
     4681 ccattactac ttagtattcc tgtgcaaata ggaatagtat atacttttct acgtataaat
     4741 gaaatatatt ttatagagta tttaccattt gcacctatat ctacaataat aggttttact
     4801 atattgatac tttttattgt aatagcatca tatatgacag gatacaatca gttgaagaat
     4861 gaaaatatag tagaatctat aaaaagtgaa acaatataaa taaaagttat ctgaacttat
     4921 ttatggtttc aattcaagaa tacttacgag tatagagata gttaaattgt ttatttaata
     4981 aaatcttaga tataaatagc ggattactaa aataataaat aacataggat atagatatga
     5041 ctggattatg ggtattttac ctataatcca gtattttatg tgtaaaactt aattatgaat
     5101 cttgcaccac cattatggca attttctgca tgtagagtac cattttgacg ttctataata
     5161 gactttgata gagcaagccc tataccaata ctgtccttac tagcgttttt accacgataa
     5221 aatctattaa aaatatatgg gagctcttcc tgagcaaacc ccttaccatt atcttctatg
     5281 ataatctcaa catatagagg gttttgacta taataagcaa tgatatgtcc accagcttct
     5341 atatgctcac tacaattttt aagaatattt aaaagagctt ctaaagtcca attaatatca
     5401 atttcaaatt ctattgaagg agaacctttg atagtaaatg tctgatgttt ttctcttaaa
     5461 gaaccttcta taggctcaat tgcataagta agaagagaat gtacatctat aagtttgctt
     5521 tcaaatatta aagtactcgc atccaatttt gataaggtaa gtaaagatga aactagtctc
     5581 tcaagtcttg atatttgctt tgtaagcctg ttaatataat ctatttcttc atctggacaa
     5641 ttttctgaaa gtaattgtgc cataagtgac atagaagtaa ttggagtctt aagctgatga
     5701 gcaatatctg caaggttatc tgaaagagtt tgtctttctt ttagagcaaa ttcttttgaa
     5761 caacgaagtt ccccaactgt tttatatatc tcatcttcaa gataagaaaa ttcatcttca
     5821 tatcttaaaa gtacagactc ttttcctaaa tttacttctt ctaagtatcg agtaagcatg
     5881 tttattctac tcaatttttg cttatttgtt ctatacttga ttatatatac aactatagcc
     5941 attgttgaaa ttataccaaa cgataccact agaaaataaa aaaagttttt actccaaaat
     6001 gtacctttag aatatccatg ttttgataaa atttcatttc ctgttttaaa atcctcatca
     6061 ctagaatttt tcagtgattt tagtatactt tctgtagatt taggattgta ctcatatgat
     6121 gcatcaagaa ccttagacag cacattgtat tcattaaaag aagtgatagt tgttagaatt
     6181 acactcaata aaaaagttac aattaagcag aatattataa aaacaactgt actgttgata
     6241 tttcttggag ttttcactag ctgtcctcca ttctatatcc tatacctctt aatgttttta
     6301 tacaaggtgg attttttaat ttttctctaa gacgctttat tgtaacagta agagtgttgt
     6361 catttacgaa attaccatct acatcccaga gcatttctag taattttgta cgagtcatag
     6421 ctctattttt attttccata agacttagaa gaagcttata ttctcctgct gtcagaggta
     6481 cttcaacact atctaaatat gccttgactt caactttatt caaacttata tttccacaag
     6541 taatagtatt attagtatta gaatgagctc ttctaagaac tgcattaatt ctagattgaa
     6601 gtactgaaag caaaaatggt ttaaccacat agtcatctgc acccatatct aatccacgta
     6661 taatgtcttt ttcatcatca cggactgtta aaaatatcac tggagtatct tctatacttt
     6721 taacgtattg gcaaaattcg tatccaatac catcaggtag atttaagtca agcagaatta
     6781 aatcagtagt tttatcaaaa ttttttttag cttcagcaat cgtattataa caacatacaa
     6841 tgtgattttt attttccagg gaagtcttta tcccaaacgt aattgtatca tcatcttcta
     6901 agagaagtat tttagccatt tacttttagt cctttcatta atttaaatta ttagttttat
     6961 gcttaatatt ttttatatta tatatagtaa agattaccat ttaagtatat aaattttaat
     7021 ttatatactt aggtctatgc tttaatcgag tctattaaaa tggcaagggt tgtttcaata
     7081 aatttttcct catctatatt aaaattgttc aggtatgatt ttcttgttac agacaataaa
     7141 ttaaaaaatc ctgtaagtgt aaatattgat gaatacataa gagtagatat ttcaatatca
     7201 tacctaatac ttccatcatt ttttccaatt tcaaacattt cttgtatttc atcaaacata
     7261 aatttattaa aagaaaaaaa cttttcttta aacagcatct cagtatccga ttttttagag
     7321 tttacaatac caatcattcc cataaggcat aatagagaag gttctacaga gtaaaattta
     7381 tgaaaagcaa agtatgaaag ttttattttt tcaaaccctg ttttaccttt tgcactttct
     7441 attttaacat tatcccaaag tcttttatat ccccttaaga caacagcaaa gaataaatct
     7501 tctttacatg aaaagtactt gtatatggtg cgtttagtat attcgacttc ctttgccaac
     7561 tcattcatag ttgtattatc aaatccatta agagaaaata atttttctgc tttatcaata
     7621 atttcatttt ctctttgtat tttttcttta tctctttttg ataattctga catataaatt
     7681 attcctttct attgataata aagtatactg gtggtatact tgtgtaaata taatatattt
     7741 gtatactatt agtatacttt aatgaaaata aaattaatat caagtattat agctatttat
     7801 aacttcatta attaattata taggcaaaat accaaatagg gggaatttat ttatgaaaat
     7861 aaaagaaaat gtattaaggt tagatagtac tcgtggctca aattgtttta ttgtgtttga
     7921 taaagagatt actcttatag acacaggtct tccttttatg gggaaaaata taattaaaga
     7981 attaaaaaca cttggtatca aacttacaga tattaagcat attttattaa ctcatcatga
     8041 tgttgaccat atgtctaata ttaaattatt aaaagagaaa acaggagcaa aggtatgggc
     8101 tcatacagaa gatatacctt ttattatagg agagaaagat agacctgggt ttaagaagtt
     8161 tattggaaag acaatttcaa gaaggctcat taaggatgtt gaaccttatg gagagaatat
     8221 gcagattggg aatataaaaa ttatccatac tcctggtcat actccagggc atgtctgcat
     8281 gatttttgaa gatgtattat ttgcaggtga tttagtcaaa aacaagaatg gaaatatagt
     8341 ttcttaccct aatccctgga attgggattc taaaaagatg atgaaatcta taagagaatt
     8401 ggataattta gaatatgaat ggatatgtat gtctcatgga actccttgta ttaaataata
     8461 aaaataataa gttgtaatat atcctatgtt atctattgac tatatccaag attggtgata
     8521 atataatatc caagatagag tataggtggt ggatttttat gatacgcact ttaattttat
     8581 attatctaaa tattaagcca acacatgggt atgagattca aaagttttta caagtatctg
     8641 gtgcagatag atggactaaa atacaatctg ggtcaatata ttatgcattg gcaaaattag
     8701 aaaaagatgg aggcgttaga gttttaaaag aagaaaaaac aggagctagg attcgtaaaa
     8761 tctatgagat tactcaaagt ggtaaattag aattaaggga agaaatacaa aaagagcttc
     8821 agatgccaat agttccaacc ggttcaaata aattcctatt acataatatt ttggatgtat
     8881 tacctaagga tactttgcaa aaaaatcttg aaaaacatat aaaatatctt atagagcaga
     8941 agaagtattg ggaaaattgg aaagagatta aaaaaattga taaaaagagt cttgcaacag
     9001 aaaaaattgc atttgatatg actatagata atctgaatta tcaaatttta tggcatgaag
     9061 aaatattaaa tgatattgat aagtatatat ccgttggttg cgagacacag aatataatta
     9121 aatctataga tttttcaaat atagaagaag attttttatt tacatctgat acgacaaatg
     9181 agttattaga agttcagaga cttagagatg aaataattaa taacccagat aaagctatag
     9241 aaaacataga taagataata ctaaaattac aaaataagta ataaatttta ttacaataac
     9301 acgggtaaaa tactcgtgtt ttaaaaaaat tatatataca atattggata tataatgttg
     9361 gttaaatatt ggggggttat aaatgagtaa tatattgtta gagattaaaa atttatctaa
     9421 gaagtataac aataaggaag ttgtgtcaat agaaagtttt aagttattgg aaggcgatat
     9481 tttaggtttc attggagcaa atggagcagg gaaaagtaca tctatcaata tgcttactac
     9541 gattgtgtct ccagatagtg gaagcatata ctataaagga aaagatatta agaatcaaca
     9601 aaatattttt aaaagttcac ttggagttgt accacaagaa ttagcaatat atgaagattt
     9661 aagtgcatat gataatgtta aatttttttg ctcattatat ggatttaaag ggaatgaact
     9721 taaagagaga actaaagatg ctttggaatt tgttggtctt tgggaaagcc ataaggagtt
     9781 tccatcaaaa ttttctggtg gaatgaaacg tagactaaac atagcttgtg caattgcaca
     9841 tagtccaaag attctcatca tggatgagcc aacagtaggt atcgaccctc aatcaagaaa
     9901 taaaattttg gaggcaatca aatgcattaa tactaatggt acgacagtta tatatactag
     9961 ccattatatg gaagaaattg aaaccttatg taatagaatt gctttaatag ataaaggaat
    10021 aattatagaa gatttagaca agagtttata taaaaataaa tatttagaat ttggttgtaa
    10081 gacattagaa gatatttttt tatatcttac aggtacagat ttgagagact tggaggaata
    10141 aatagatgag atgtttttta ccattgttta aattaggaat aaaacgaaga agtaaagatt
    10201 tttttattct gttttacaat attgtttttc cagtaataat cataatgtta ttaggatatt
    10261 tgacatcaaa gtcctatggt gaggaattta catcatataa ttattatact attgttacaa
    10321 taccattttg tgttcttatg ggaattatta gtgtttcata tgcgggacaa gatgaaaaaa
    10381 tttctaacac atcatatcgt tatatgattt ctcctatttc aatagtagat ttagttattt
    10441 caaaactttt ttcttgtaca gcagtacttt cgatatgcaa tttggtaact ttagtggtgt
    10501 taaaatgtat ttttcgtatg agttttggtg gaaaattttt agctgttctt ttctttttaa
    10561 tgtgtgaatc tattgtggta gtatctatgg ggttgttttt gggtcttgtt tgtaaaaatt
    10621 tagatatgtt acgtaatatt attaatatac cgatagttat ttttggattc ttaggaggag
    10681 tgttctttcc agttagttca ttgaatccag ttatttcatt aatcattaat atatcaccat
    10741 taacatggat taatagaggc atagttgctt gtatctatga taataattta caactccttt
    10801 ttaatatatc atgcatattt gtagttgtaa gcatatttat gacaatactt acaatcaagt
    10861 tttttaaaaa gggggtcttt atatagtgaa tgtaataaat gtttttaata ttaacttaaa
    10921 aagaaatata aataagagaa tagtattttt agttacactt ttatttccta taattatagt
    10981 aattttggga gtattggcaa attacataag taaaccattt tttaatattg gtattttaga
    11041 tgagtacaaa aacgaacgag ttctaaagga atctgaaaaa agaacctatg aaaatacaat
    11101 aatggcttta gaaaatactc aagggattaa tacaaagatt gcagatttta aaacaattaa
    11161 aactgatatt ataacaggca agtattcagc tgtcatatat tttaataaga atggttttaa
    11221 gttatattct ataaaaaata aaaatacgaa tgatacatta aagtatttaa tagaaacata
    11281 taaaaaagac ccagttcctg tagatataag taaattacaa gaaaatactt taggagtttt
    11341 acaaagaata attgcattta tcgtattatt tttaatgata acatctactg taacagcatc
    11401 aatgattatt aaagataaaa actcaggtac atttacaaga gtgctgtatt ctccacaaaa
    11461 tgtaagagga tatgtgctag ggaatatgtt atacaacttt acaataacgt attttcagta
    11521 catagtttca atatctataa ttaagttatt taatattgat attggtatgg attatataga
    11581 tttaatttta atgggaatat gggtagtagc tttggcaact tcttttggaa catttgtatc
    11641 ttctttattc aatagagaga tgcatgcaaa tttattttct acatgtatat cacttgtatt
    11701 atcacttatt ggaggttcat tcatctcagt tgaaaaaatg ccagaaatgt tgcaaaaaat
    11761 tagtattata agccctgtaa ggtggtttat tagttttgtg acttatatag aagaaagaga
    11821 tggaagcttt tttaatatga attatatttg tattttgacc tctataataa tagttttagc
    11881 tttgttagct atgaaattta ctcaaagaag taaatattca agtaatagta attattaaat
    11941 aagataaaaa ataaatatat gtaattaaaa caaatcaaga gataaaaata taaatatggt
    12001 tctatatctt ataaattggg tttaattata aaaatagaaa ttatatagtg taaaaaatag
    12061 tgtgaaaatt tttttatttt ataatatagt gtcacatgag caaattaaat ttgttctgag
    12121 atagctcttt tttatttatc ttaatagaaa tatttttaat tgttttatat aaagtttatc
    12181 ttctaaataa aattatgtat aacaaataag ggtataaaaa tactattttc tagggacaat
    12241 ttgatagata taaagatctt ttgagacaac atagattaaa atgtattaaa cacttgttaa
    12301 aagtaagaat tgaatattta aaagagaggg gagttttata tgaataattt attttatgat
    12361 aagctaaatt ttgatgataa actaatcatc aaaaataatg gagtaatcag aaataacgac
    12421 ttatattttt taaaatataa aaacgatacg gcaggaatct taatatataa tataataaat
    12481 gataaattct catttaagca aaataaaaat tacaagggaa tgaacccatt tccaatcaca
    12541 aatattttca agaatttaga tagtgataaa tgggatgaat ttataagaat ttggattgag
    12601 gaaagagtta ttcaagaatg cagaccagag gttcctttta tactaaaaga atttaaacta
    12661 ggatattatg acgtttggga tatttgtaga agtaatcttg ctatgagtgt agaagatttt
    12721 ttctggatta caaaagataa cactctaaga tatgaagatt ttaacatccg ttattgtact
    12781 ttaaataata ttactcctat ttataagcct ccttttccta ttgttatata tccaaattat
    12841 tttgagagag aaaaaataaa aagtggtgaa acctggaaat atgaactaaa aaatactaat
    12901 tcttaaacgt ttttagatta tacattctta tttgtactat aaaaaataat gttaataatt
    12961 aaaactgtta ttaagtgatt ataaatcatt ttaataacag tttttttgat tttttataaa
    13021 aattttcaaa aaagacttct aaatgcccca tattatatac aaattaaatt aaagctatac
    13081 tttagcaaat aaaaataagc tgtaactatt agcataaaaa ataaaaggag gtttttatga
    13141 aatcaaaaac tttatcttta ctctatcaaa aaaattaggt gaaacattta aaaactttaa
    13201 cgaaattaac aaacaaaata ttcttaaaac aaggagattt ttattcaatc taggatttga
    13261 agtaaaatat ccagctggaa caaacactgt tttaaaaaaa tttaaatcta aggaaaataa
    13321 tgaagaaaaa gaagttacat tattttactc aaaattagat agtacaaagg atatttaaat
    13381 attgattata tctgtagcat catgaatcaa tcatatcata atatcaaaaa tgaattatta
    13441 tctaaacaac ttgcttatat tgaccgtttg acaggatatt tagtagatag agataattat
    13501 ttgagtggat atgttaaaga aaaattaaaa atagccaaag aagcatcaat aaaagataat
    13561 actttcctgg ttaatgttaa agctttagaa gctaatcaac ctaaatatga aacagatgtg
    13621 ttctttagca ttgattctac ttggatatct tcaagtataa aatctgattt tattgaaaaa
    13681 acattagaac tcaaagaaaa ttcaattcaa ttattgtatt caacacaact tggttattca
    13741 gtaaaatgtt ctgacattat acctataagt aaaaatgaat ttacatgggg tacaaaaagg
    13801 agaaaatctt tgtatattgt tgaagcagaa ttaaatatga aaactataac tgtcactgat
    13861 aaagaatatc aaaatggtaa agaagtttct gttaaaaatt tggaagaaac tcaacttgct
    13921 atgaacatat taaataaatg gcttatagct tttcataact atgtaacaag taatagttat
    13981 attcataaag aattacttga tagatacaat gaaatgttta tagattataa ggaaaaggaa
    14041 tataaaaata tattaaatga tgttagaata aatcctaata taaaattacg agaacatcaa
    14101 ttaaaagcgg ctagtagaat aattacttct gatcgtaata ctcttctatg tcatagtgtt
    14161 ggttctggaa aaacttatac aatgataaca gctgcacaag aattaaatag aatttctaaa
    14221 atagattcaa agaaaggtaa taagaattta tttgttatac caaattcact ttgtgaatct
    14281 ggacaatttg ctaaagagta ttttaattta tatcctcaag cgaatatatt agctacaact
    14341 tcaaaggatt tctctaaatc caatagaaga aaaattatag ctaaaattgt gacatgcaac
    14401 tgggatagta taataattcc acattcggta ttaggattaa tccctttaga agctgataca
    14461 gaattaaaat tattagactt atacttaaaa gaattaaatg atactcttaa atattacaaa
    14521 aaagaatgcc ctgatctttc tacaaaacga cttgaaacaa tgaaagaaaa ttatctaaat
    14581 agaatcaaag agctaaatga tatgcataaa gacgatgctc ttctttcatt tgaaaagctt
    14641 ggaataacaa acttattcat agatgaagct cacaacttca aaaatttata ttttaataca
    14701 actatgcaag tccctggtat atcaacttta aaaactaaaa aaacacagga tttatacaac
    14761 aaactaagat attttaaatc tattcatgga aataaaggtg ttacatttgc cacagctaca
    14821 cctatttcta atagtatatg tgaaatgtat actttactca cttatttaaa taaagataca
    14881 ttaaagtatt acaaagtaga tactttcaat gcttgggcaa gtaaatttgg ttcaattata
    14941 tcctcaatgg aagtagatcc tactggtcaa gggtttagat ttcagcaaag atttgctaaa
    15001 ttctgtaatg ttccagaatt agttaatata ttcagacaaa ttgctgatgt agttaacatc
    15061 tgtgacataa atgatttaga tattcctcag ataaaaggtg gaaaacctat aatagaaatt
    15121 ataaaaccta caaaccaaat gaaagaatat atagattctc ttgtaaaacg tgcagaaaaa
    15181 attcatgaag gcccatatga tccaataata gataacatgt taaatgtaac tacagatggt
    15241 cgtttgatgg ctgtaagccc tgcattagtt ggaattgatg gtatattacc aaagataata
    15301 aaagttggag aaaatatagc ttctttatat catgaggata aaataagtac acatctagta
    15361 ttctgtgatc taggaactcc taatggaaat tcacataatg tttataatga tataaaaaat
    15421 gaacttctaa aaaataatgt tttagaaaaa gatatagcat acatacatga cgctaatact
    15481 ccagaaaaaa gaaagaaact tattgatgat ttcaataatg gtattattag aatattaatt
    15541 ggttctacct ctaaaatcac ttcatcatgt agatgttcct tggaaacctt catcaatttc
    15601 acaaagagaa ggtagaatat taaggcaagg aaatttgaat aaagaggtct atatttttag
    15661 gtatgtagtt gaaggttctt ttgatgcata ttcgtgacag acaatagaaa taaaggcaaa
    15721 atatatagct caaattctta ataattcttc atcttctagg actgctgaag acataggtaa
    15781 tcagcttatg agttatgctg aaacaaaggc atgtgcctgt tctgatgata gcatattaaa
    15841 attatgtgag ataaatagag aaattcagat aattgaaata aataaaaaag cctttttaaa
    15901 tcaaaattta cttactttaa atgacataaa atcaaccgaa aattcaatag atgctttaaa
    15961 gatatcaatt tctaaattag aagaagatat taaaacgtat ttttctaatt ttttttaatg
    16021 aatttaagat aacattagat aatgaaactt atattgatat taaagatgct atagaagctc
    16081 tgtcagatat aataaataat ggaaaagtag gaattttagg tgaaatatat ggcttgaaca
    16141 taatttatga aaaagaattt acatttgaca ataaagttag agaattcatt tctctaggta
    16201 ataactataa atttgaattt tctacatcaa aaagtcctaa aacactaatt aaatatttca
    16261 tggattataa taaaattagt tcaaataaat tagaaagttt taaagaaaaa tattcattta
    16321 agaaaaatga actcttatct ctccaagaaa ttttaaagaa taagtttaca gaagatgata
    16381 aattagaatc tcttaaactt tcaaaagcaa atcttgagaa tgaattaaaa ttaggaaatt
    16441 ctataattaa aaaaagcaac tcaaatcata atatggtaga aaaaaaatga attaatattg
    16501 caattgtttt aaaattgttt tatgcatgtg tagtataaaa ttccaaaata aattgagtat
    16561 tttcaatact tttagataca gaaagtattg aaatttgtaa tgagcacaaa gtggtgtttt
    16621 ttatattaca aaaaagacct tgtaactcaa tatctgcaac ccttttaatt aaaactttaa
    16681 aatatatgaa atcagaaaaa tgattttagt ctatttatta gatattcttc tctctcaatg
    16741 cttaaagctt ttagatatat aagactatcc tgtttatttg cacctgttat atctttaaat
    16801 ttaatatagt ttttaatatt cttgcctcta aaaatatatt tattatcaat caaaatatca
    16861 tcatctgtaa ttgaaatata aagtttattt ttatatttta ttaaaattta tacgtttgtt
    16921 caagataaaa acctgcaagt aacaaaaata gaaaagttac tttgaatata catattattg
    16981 aaaatcactc ctacaattta tattgaccta tgttattcaa aatactttac tctacttgca
    17041 ttaaagatgt aatattagtg aactaaatta atataatttt ccattcaaaa cgtgttattt
    17101 atattcacat aattacaata gaaataccta taaggattat tccaataata cataataaaa
    17161 gtgtctccat tagattttta ttaagcttat aagaattata agctagtaaa atttgttcca
    17221 ctccaaataa tattaaacaa aattttaata aattaaaatt tttaataata ttagtacaag
    17281 aaagtgctga tattaaaact attaagatag aaattaataa agttaatatt ttaatttgct
    17341 tgttatagaa catactattt tccccctcat tttaaatgca tactataatt ataaacaaat
    17401 agaatttatt caagtaaaat atttctcact atttttaata tgataaatca aaagagaaaa
    17461 aagcacctgt acttacagat actttttttc tgatttcttt taatgctcct aaatatgttt
    17521 tttcgttttt gtttatctgg gataataaat tcataatttt ttcattagtt aaaatttgag
    17581 tactagaaat atttgtgtct ctcatcaacg ctatgtaacc tgtaataata gctgttgctt
    17641 ctgatgttcc ctttccatag aaaacattat tgttattatc tatcaccttt attttttctc
    17701 caggtgcatt tattaatgtc ttttgaggtg catttgtcaa tgttgaaata tctcttctat
    17761 catctatgct accaacagaa ataacattat ttaaagatgc tggaaatagc aaaaatcctt
    17821 gtttataatc acctgctgaa cttacaactg ttatattttt aagattagct ttatctattt
    17881 tttgttttat attaatatct gtttttgtgg atcctaaact taaactaata atatctactt
    17941 tttcatttaa tgcatagtct atagcatctt ctattacatt aggattaata ctttcatcat
    18001 cattcattac tttaattaat attattctag aatctggaga tattccttca atcgtttgat
    18061 tatttttatt ataacctttt atgattgaat acatcatcgt tccatgacca tttgtatcat
    18121 aatcattatt gctattagtt aaatttatat ttttataaac cttttgaaat tttgaaatac
    18181 cagaatctat caatgctatt ttttgacttt tcccactaga tatttcatgc atatcactat
    18241 aattcatata attaacatac caacagtcag attttatatt attaaaaact ataaatatag
    18301 ataaaattat taaacaagat ataaatatta ttgttttaag attttttttt tataatttaa
    18361 gttttgtttt tcactcatta atttcaccta atttttactg attttttact gcataagtta
    18421 accaccagtt tatatccaca gttattcctc tattatttcg tgaatttaca taagatactt
    18481 tatttgcaag acctcccata tatgcagctg ataaaccaga tacaaatcct attggtgctc
    18541 ccatagaacc taaaagaaca cttactgctc ctgttgctac aaatccttgt gaagacttat
    18601 tcaaatcata aacccatcta tttgctgctg cagtactttt attttgtctt actccccatg
    18661 aaaatttttg agtatatgta gaacctcctt gtacataaaa tgagttgtct gtattgttta
    18721 taatatcttc ctcaggtgta attttaagag ttttattttt tactccttca tttatatcat
    18781 ctatattttc tttaactaaa ctatatatta cgtcactatt aaaattattt atgaattttg
    18841 aatcaattcc ttgctctatc atttgttctt taatatcttc taagttaatt tctttcaaat
    18901 catttttcaa gtcagaagaa acttcaatac cctctttggt ataagataca tttgattcta
    18961 taacatttat tatttggtta tttacatttg tgtctttttt ttctaatgca ttgattgaaa
    19021 ttactggaat aagcaatgca attgatagtc ctaatgcaat tactttttta aaatatttca
    19081 taataatatt cctcctaaat tttaattaaa ttaataattt gttacattac ttgttatatt
    19141 cctactttca tttccagctt ttattgttgt taatattcta taagaatacc cctttgatac
    19201 tctatattct ctagataaag tacttgaagt ttttcctgag cttgaccatg ttgatatagt
    19261 tacccactta ccagattttt tttgctgtag tcttgctgta attgatgtta aactcccaat
    19321 tttaccatca acataacaag atatatgagc ctttccagaa cgaatactca aattactacc
    19381 agcaccttta atataaatca taaataaatc attatcattt gtttgattat aatcattagt
    19441 atttaatgaa gtatcttcaa aagcttgaac atttaaaggt aataggcaag ttaatgtaca
    19501 taatcctgct acaatcactt tttttaaata cacaaatatc acctcctttt ttcttatata
    19561 ctcatataac gaaaaaaaag gtgatttgtg acactttttg aaaaaaatta ttttatattt
    19621 tcagcaatat ctataagatt atctttatac ttatttaaat catttttatt atcataatca
    19681 aaatatattg tatatacatt ttcttcatca ttccaaaaaa ttgtaatact attgtcttta
    19741 acaatatatt tagcttcata atcatttacc ataatatctg tgacttttgc attctctgta
    19801 tctaatatta ctgtatttga atcaatttga ttggaacgat atcttatttc agagccattc
    19861 ttgttttcat agcgaataaa gataccttgt aatgtgtttt ctttttcaac ctctttgaaa
    19921 ccatttggta tatatttggg ttcttttaat ataaaatcaa gattcttatc agtttgaata
    19981 tctttagaaa aaataaattc tgttaaatct tcataaattt ctattacaat tttgataaat
    20041 tgatttctaa gggtatcaac actcatagtt attgtgaata atccagttat aattattaaa
    20101 aacacaactg caactcgttt taaataaata atagtatatt taataaagaa gttactcaaa
    20161 tatcttttga aatagatata ttaaattggc taaataaatg tgtctcacat catgaaacta
    20221 taaaaatagc tccaataaga gaaattatac tgcaatttat ggaggtaata agaaatatga
    20281 caaatgtatc atcactagaa aaagaggatg agatagtaga aattttatca tctaaagaaa
    20341 atataagagt agcaatagaa attgaaagag gattaaagtt atgtaaaaca caaatgataa
    20401 aaaaggtttt agaagaaatt gaaaaacgta tggataagaa atttgaagat aaatataaat
    20461 taccatatta ctcatacaaa gaaaataatt atgctttagt gaataattat tataataaga
    20521 aaagctctac atatccagca attaattatt ttataaaaag tctagataaa gaagatgttg
    20581 atcttttact aagaattgaa atagatcatc atatatttgt aggtttttgt acgttatata
    20641 aagaaaaacc tagcggaaag attctaagtg atgatgaaat aaaagaatta ataaatgatg
    20701 atggttcacg tactaatgga tggtggattt gttgggaata catttataat aatactatgg
    20761 aatgtcctaa tttcaaaaat tttaatgatg cttattttga tttatttgat gataataaat
    20821 ttgatgaatt tatggattta tgtgaaaaaa gaattttgtc aatattaggt aaactaaaag
    20881 ataagcaatg cataaatact tttatctaaa atagaatatt acctaacaag gtatgtaaat
    20941 gtataagact caaggatttt gataacaaat aagagattac atgatttgaa gatatgatgg
    21001 aagaatttag atatagttta acaattaata gataatagac tgaaaaggat ggtaattcta
    21061 tgaagattga aatgggagaa tcactgttgt attcttggct acgtcatgtt aaagaatgcc
    21121 aaatagtgca aacaaactgg aaagtgtcat ctaaatggga tttaaagaat gctgataaaa
    21181 tactagaaat tatggaaaaa actaaacaat attttgagca gaaatatgga tatcctatat
    21241 ataaaaataa ttcattggag caattaatta tgcaagctga agttgatgta ttaggtattt
    21301 caatagataa tggaagaaat catatttatg ctatagatgt agcttttcat gaagcaggac
    21361 ttaattatgg atctaaaaat gaaactgtta caagggttat aaagaaatgt atccgtacag
    21421 caatgtgtat ttatggttat atggacttag atgaagcaga aattatattt gcatctccaa
    21481 agattaatcc agctattata actgaattag aacctaagat ggcagaagtc aatgacctat
    21541 ttaagtcttt aggattgaga tttaaaacta gattaattgc gaatgaagaa tttaatggta
    21601 aaatcctaga accaatctta attgctagtg atggaatctc tgacacatca gaacttttcc
    21661 taagaagtta tcaaatgtac agtatgtttt catatagtcg agatgttgta aaacaacaaa
    21721 gaataaaaaa atctaattct ttaaaagatg cagttgaatt aaatttgtca gatgaaacat
    21781 taaaggaatt aaagattggg aaattagttc aagtaactat gaaacatctt tttgaagaag
    21841 aaaaaattag ccctgaagaa attgataaga tgacacaatc cagttattca aagcaagtgt
    21901 ttaatgaaaa taaacctgta ctaaaagaag ttcctaaaga tggtaatatt aatgaattga
    21961 aaaaagatga aaaaaactac aatagatatt atgcttacac tatttccatt tatggaaagc
    22021 aatatttatt agtatcacaa tggatagaag atttacatcg ttcatattat gaaagttggg
    22081 ttatcaaata aattataatg ctcttgctaa atctaagaaa aatgcaataa cataaaagtt
    22141 aaatttaata aaatagttag ttgtacatta aacattttta acttaatgta ttcatcttct
    22201 attacacaca tttttatatt aaaagaatac aaaatataac ttattaagta aattatttag
    22261 gcatttaaaa agccactccg gcaagagtgg ctaggaattc gatttaaaaa tcaagttcaa
    22321 aaaatttaaa taatttttta ttttaaatta cgaactcaat tctgtcacta aatagaatat
    22381 agttctcttt cttttactgt tataacacaa aaccttaatt ttgatacaat tttatattgg
    22441 attgccaaaa ctccctattc cagggttatt aaatataaaa gttttttata taaactttaa
    22501 gatagtataa aaaataagag gtattaatct cttgtttttt tatgattttc tttataatac
    22561 ataataat
//
LOCUS       DAMKOJ010000246        21213 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.063, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000246 DAMKOJ010000000
VERSION     DAMKOJ010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.063"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            824..1225
                     /locus_tag="PC592_003778"
     CDS             824..1225
                     /locus_tag="PC592_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF4057661.1"
                     /translation="MNYKNRKRAYYQENSCLDNFICKNCGCIVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNP
                     VKLMSIALKPLAQPPFPLERITEKMEKEETE"
     gene            1222..2289
                     /gene="rsgA"
                     /locus_tag="PC592_003779"
     CDS             1222..2289
                     /gene="rsgA"
                     /locus_tag="PC592_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF4057662.1"
                     /translation="MNGMKEIDLQDYGLNSNFITQSMKYHDLYIARIISQEKNLYQAV
                     CTGGIVFAEVSGKLRFEATIPSDFPTVGDFVILDRCNDKNGNAIIHHVLHRKSLFVRK
                     AAGKANEEQVVAANIDIVFLCMSLNKDFNTHRLERYLSLTWESGAVPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSAKESDGCQQISKYIKPGYTIALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIADDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGVDKS
                     FADIEAYFGKCHFRNCSHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
     gene            2832..3530
                     /locus_tag="PC592_003780"
     CDS             2832..3530
                     /locus_tag="PC592_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057663.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESIVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKDRQEVYTKKINEAIKNLYKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLYENSTYLNTSDEKESLITKEFNEKVEEEMLNDEKLEELEQKKDYKEDSNKK
                     EKISEDLSLAGKTREELENMLKNFTNLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLL"
     gene            complement(4109..5065)
                     /locus_tag="PC592_003781"
     CDS             complement(4109..5065)
                     /locus_tag="PC592_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF4057664.1"
                     /translation="MKNNTTQKRLRDLSKKIWNIYILNPEEEGIKFIISLLDDNLTLI
                     GTGKHEFYETLEEFIIGLEKDQVESNQIDFEIIDEWYSCTKVTDETFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVKDDIIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHI
                     RGDEILIHFSNILTKVFISDAIIGRLGGDEFAVFEYSNQSKEDVENKAKKVLELCLEN
                     NSCSIGISRLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            5768..6763
                     /locus_tag="PC592_003782"
     CDS             5768..6763
                     /locus_tag="PC592_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF4057665.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFIGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAIV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSEYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAVAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEELFNHFQKYKKITVSFSNETNIVFSKDCKVVEQT
                     NHKTSVVVPKERGNETIKWIFDRYDVKDVMIEEEDIVNIVERIYKKGSDEYYEQL"
     gene            6741..7604
                     /locus_tag="PC592_003783"
     CDS             6741..7604
                     /locus_tag="PC592_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF4057666.1"
                     /translation="MSIMSNYNEASSNSSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMMFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLSGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKINFAFT
                     SNPIQILISIFMIFLGLIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVKVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            7601..8395
                     /locus_tag="PC592_003784"
     CDS             7601..8395
                     /locus_tag="PC592_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF4057667.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPIDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVIIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFSFTLFMWRFWKLGLRHYKSASS"
     gene            8678..10057
                     /locus_tag="PC592_003785"
     CDS             8678..10057
                     /locus_tag="PC592_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF4057668.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCHSYIFIILIFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGVLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLISEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNMLNINGIWLAVPSAEILTLFLTVFCIC
                     KHKNRYKYM"
     gene            10507..11220
                     /locus_tag="PC592_003786"
     CDS             10507..11220
                     /locus_tag="PC592_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4057669.1"
                     /translation="MDTYFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIVFRVKAQLRRQQYQSIVPSDSSVIKIGDITIDIEGNRVYKDRKEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(11497..13035)
                     /locus_tag="PC592_003787"
     CDS             complement(11497..13035)
                     /locus_tag="PC592_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF4057670.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVIPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQESAISGNEQHLIKASDYQEQLIANNFYSIDNEVNKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHEVLLLDEPTNFLDKEHVEWLSNYLNTFSGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKLHLREDYIRRYQSQQKKIEKEEAFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPGFTGKPNIKFSEIEISAQNALTVTNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPCISGDFQFSEQVKLAYYEQDL
                     KWENPTKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLFPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            14043..14329
                     /locus_tag="PC592_003788"
                     /pseudo
     CDS             14043..14329
                     /locus_tag="PC592_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            14317..14643
                     /locus_tag="PC592_003789"
     CDS             14317..14643
                     /locus_tag="PC592_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF4057671.1"
                     /translation="MSSYLNLIREFNLKEKIIAFICVSALLIGKSCVLKNRKATTYHL
                     KNSKRQRQLSEFDVNVVNEPTVVNQNIITSYYTETAPHVAFKLLEMLISKKQLDEVKL
                     AMGFKL"
     gene            complement(14648..14971)
                     /locus_tag="PC592_003790"
     CDS             complement(14648..14971)
                     /locus_tag="PC592_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057672.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLEKL"
     gene            15123..15641
                     /locus_tag="PC592_003791"
     CDS             15123..15641
                     /locus_tag="PC592_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4057673.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLDKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGLNKLSKAANIYDAPLAILVCGDKEKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKVADSPDRHEKTR
                     VPLSEIVSYEIL"
     gene            complement(15832..16500)
                     /locus_tag="PC592_003792"
     CDS             complement(15832..16500)
                     /locus_tag="PC592_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057674.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLILKNSTIKN
                     IIEKHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKIELPLKIDLANGSEHFYGIGAKEQILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKYYISSAFPDLKINS
                     IDIF"
     gene            16615..18030
                     /locus_tag="PC592_003793"
     CDS             16615..18030
                     /locus_tag="PC592_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF4057675.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILNGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNYIFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRAEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGVKVDDKGINTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKYATENGYYII
                     EDDYDSEFRYEGQPISSLYELNPNKVIYIGSFSKILSPAIRVGFILLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIEKILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHINQGT"
     gene            18253..18711
                     /locus_tag="PC592_003794"
     CDS             18253..18711
                     /locus_tag="PC592_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF4057676.1"
                     /translation="MEIIDYIEENLTENLNLDKIADIANYSKYHLHRMFTNIVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITAGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKYISYANMNCKQRIDEINSYLNFNINCEVKVA"
     gene            18708..19292
                     /gene="clpP"
                     /locus_tag="PC592_003795"
     CDS             18708..19292
                     /gene="clpP"
                     /locus_tag="PC592_003795"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF4057677.1"
                     /translation="MSLVPHVIEQTSQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSVTAGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRYALPNAEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDRIFSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            19595..20671
                     /locus_tag="PC592_003796"
     CDS             19595..20671
                     /locus_tag="PC592_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF4057678.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGSPTLSYYRERLFKRSSNHKWVDPIHEVVPLSGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKVLEPRHQFYYSRELYYNAKYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPYIQLSVCYDRLGESNKAIYYHEK
                     TKEIKPNDSAVLHNENYFNKFKNS"
     gene            20738..>21213
                     /locus_tag="PC592_003797"
     CDS             20738..>21213
                     /locus_tag="PC592_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore surface glycoprotein BclB"
                     /protein_id="HDF4057679.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNSGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGGTGRGGPT
                     GPTGPTGPTGPTGPIGFGITGPTGATGATGATGADGVTGPTGPTGATGANGITGPTG"
BASE COUNT         7846 a         2463 c         3337 g         7567 t
ORIGIN      
        1 taaatttctc tagttttgcc gatttagttt tattctacaa ttacaataat acaatagaat
       61 tgattattat tcaatatact tgtttgaaaa ttaaataaat ttataaatat gaacgttatt
      121 ttatataaaa aaatatacta ttcatgtaag aatatatgga agagcttgat tatacgtttt
      181 gtttaaaaga cctttgttat taacttaaat tagataaatt gagggagaga tataagatga
      241 taaaagaaat aatagcggtt aatttttatg attaatattg aatgaatatt gaatttcaaa
      301 agattactag attctataga ataaaaaaat aagataaaca taaatatatg aatatgttaa
      361 attatacttg aacatactca tattttatga taaaatttca ataataatta ttagtaaagg
      421 agtgtcttgc ctggtgtcag agttgtatat aatggtaacc aacaaataaa tagttggagg
      481 cgcatatggg ttctgtttaa tcagaatttt taagtgtatt tttgatacat ttaattgttg
      541 tgtcttactc tgcctttata gataactaac attcgacaac aaataataat attacatatt
      601 actttgttaa attgtggtgt agtgggcttt aatctgctac acttttatta attttacata
      661 gtattatttt gaatatagtt atgttgaaat agaagatatt aaattttcta gtccacagga
      721 gttttctgtt tttgtgtagg caaatatata taccacacaa aaaggcagat ataaatacct
      781 gtggattttt ttgtataaaa cacaagatat ggaggcgata aaaatgaatt ataaaaatag
      841 aaaacgagct tattatcagg aaaattcctg tttggataac tttatttgca aaaactgtgg
      901 ttgcattgta gtacctgaag gagctggtac acaacatagg aatcattgtc cacattgctt
      961 acatagtctt catgtggata tcattcctgg tgaccgtgct gcagattgtg atgctaatat
     1021 ggaacctatt ggagtgtggg tgagaaaaaa tggcgaatgg gcaattattc atcgttgtac
     1081 acgatgtgga catcttagtt ctaaccgtat tgcagctgat gataatccag tgaaattaat
     1141 gtcaattgca ttaaaaccac tggcacaacc acctttccca ctagagagaa tcactgaaaa
     1201 gatggagaag gaggaaacag aatgaatggt atgaaagaga ttgatttaca agattatggt
     1261 ctaaatagta attttattac tcagagtatg aaatatcatg atttgtacat tgctcgcatt
     1321 atatcacagg aaaagaacct ttatcaagct gtatgtacag gtggtatagt ttttgcagag
     1381 gtttcaggaa aactacgttt tgaagctact ataccatctg attttccaac agttggtgat
     1441 tttgttatac ttgaccgttg taatgataaa aatggtaatg ctattattca tcatgtgctt
     1501 catagaaaaa gcttgtttgt gcgtaaggct gctggaaagg caaatgagga acaggtagtt
     1561 gcagctaaca ttgacattgt ttttttgtgt atgtcactga ataaagattt taacactcat
     1621 cgattagaga gatatttgtc tttaacatgg gaaagtggag ctgtcccggt agtagtactt
     1681 accaaatcgg acttatgtga caatgtacat cgtaaattac aagtagttaa ttctatagcc
     1741 ttgggtgtag atgtagttgt tacatcagct aaagagtcag atggttgtca acaaatttct
     1801 aagtatatca aaccaggtta tactattgct ctgcttggtt cttcaggagt tggaaaatct
     1861 tcattaatta attgtctgct gggtggagaa tttttaaata caaaggaaat tcgcatagct
     1921 gatgataaag gaagacatgc cacaactaga cgagagttat ttttaatttc aggtggtggt
     1981 attgttattg acacaccagg tatgagagag ttgggaatgt gggatgtttc ggaaggtgta
     2041 gataaaagtt ttgcagatat agaagcttat ttcggaaaat gtcattttcg taattgttct
     2101 catacttcag aaccaggctg tgctatttgg gaagctattg ctcatcaaga actttcgcct
     2161 aaaagatggg aatcctatcg taggcttaaa actgaggcag tatttgcaga caataaaagc
     2221 gaatacttag caaaaaaaga aaagaaattt aaaaatatct caaaaataaa taagacgatt
     2281 agaagatgag tgtagttttt ttgttctgtt cgttctatga ctctatatat tattaatata
     2341 ttagatttgc catcaattta ttactttaat gtgattttga tggcaaattt gatttatggt
     2401 attatttaag gcaatttatt aattttttta ataaagtttg actttttata taatgatata
     2461 tacatatgat aatgtataca tgtttgttat gataggttct tttataaaga gttcttatgt
     2521 gagataagaa gaggcatatt tatactaata cataatagag tatatgctta tgtatgatag
     2581 agatgtttct taaaagcaaa actgtaatat tgataatttc taaagtaaaa atatataaat
     2641 tataaaatat aaataagata tttataaaaa ttattgtttt aatttataat aaaaattttt
     2701 tgttgaaaat aatgctcgaa cctatagaac tattaactaa tatttgtaaa tgtatacttt
     2761 tgatgataaa atataattaa gttaagttgg ctttttataa aacataaatt tgttttagag
     2821 aggtgaaata aatgaaaata tctagtcaat atagaagtca atattcattt agacatgaaa
     2881 gtaatataaa taatacaaga ataaatgaaa gtatagttaa gaaaaatgaa actgtaggaa
     2941 aagacactta tttatctaat attatgaaac aaaagcaaga acttaatgat agaattagag
     3001 atttaaaaga tagacaagag gtttatacta aaaaaataaa cgaagcaatt aagaacttat
     3061 ataaatcaga aataagagaa acaactaata acttttctaa tatagaaata ggtattaaaa
     3121 atagcattat agaagataaa aataaaagta caatgttata tgaaaattca acttatctaa
     3181 atacaagtga tgaaaaagaa tctttaatca ctaaagagtt taatgaaaaa gttgaagaag
     3241 aaatgttaaa tgatgaaaaa ttagaagagt tagaacaaaa aaaggattat aaagaggatt
     3301 ctaataaaaa agagaagata tctgaggact tatccttagc aggtaaaact cgtgaagagc
     3361 ttgaaaatat gcttaaaaat tttacaaatt taacacaaga agaaataatg aaacttgagt
     3421 cgagaataga aaagttagat aaagatgctg aagaatacaa acaaaattca aagactaata
     3481 tatttgataa aacagatgaa caaaaaaaac atataaatgt actgctttaa acaatatgtt
     3541 ttaataaata agtttattat attatgaaaa cataaaggta caatttcaat acacttctat
     3601 ttttggtgga acattagatt ttgattacct taagttaaag gatgcgacga gagagatgac
     3661 tacttactat gatgctaagg cattgtctat attaggattt aatcaataaa aatatggaag
     3721 gcttcttgtg gaatcttttt tttattaatt tgaaatttaa taaggaattt tatattaaat
     3781 ttaatcaata aaagtaaaaa aggctattta tagagccttt ttaagtattt ttttagtaga
     3841 attttttata tcagcatcag ttttaatcaa aaaatataat attttggtgt tatttttaaa
     3901 aataaaatta ttaaaatata atattaatca tgttaataat atttttagtt tataatattc
     3961 tataatagtg ggtatgatga ctattgtagc tctattaata atagttggtt tatataaata
     4021 tatgcaaaga taggttgttg tttaccttac ctattagtac gtaaaacaag atactctgag
     4081 aaatttgcct attttaatat cttttgcact aaaaccaact aaagtttcct ttattatttc
     4141 gttttgaata atataaagca taatccgatt gtttgtataa agattggaaa gtatcagagt
     4201 tattttctaa tctagatata cctatagaac aagaattatt ctctaagcac aattctaaaa
     4261 ctttttttgc tttattttca acatcctctt ttgattgatt actatattca aaaacagcaa
     4321 attcatctcc accaagtctt ccaataatag catcacttat gaagacttta gtcaaaatat
     4381 ttgaaaagtg tattagtatt tcatctcctc gaatatgacc aaagatatca tttacctgtt
     4441 taaaattatc taaatcaaag atataaaagt atccgtgtga aacggtttta agcatttctt
     4501 ttatgtgtac ttcaaaaaaa tgtctgttgt atagtccagt cataaggtct ttttctgatt
     4561 ttagtttaaa ttcatttgcc attgctagtg cttcttgtgc tttttcagtt attgttttag
     4621 ggtaatactc atctttcatt tggtcaaagt ttggaataga atggtgaaca tggataagtt
     4681 taattatatc atctttaact ctgtatacca tagtaaagcg agtatccatt tctacataga
     4741 tatctttttc taggtaatct ttttctatta cccaaagagt accatatact ataaaagttt
     4801 catctgtgac tttggtacat gaataccact catctataat ttcaaagtct atttgatttg
     4861 attctacttg gtctttttca agacctataa taaattcttc taatgtttcg taaaattcat
     4921 gttttcctgt tccaattaat gtaaggttgt catctaacaa agaaataata aatttaatgc
     4981 cttcttcttc tggatttaaa atataaatat tccaaatttt ttttgataaa tctcttaatc
     5041 ttttttgtgt tgtattattt ttcatagatt acccccttaa gatttacagt ttatatatta
     5101 atgtattata agttgaaccc ttattacaat cttattataa tatagaactg aagaaattac
     5161 atcctgtata ggtaaaaagt atatctttta tgataaaaag attaaagaaa aataacaagt
     5221 tttaatatgc atattatatt cttaatttat aaatgaatat tataaatgaa atttaaattc
     5281 aaccctgagg aaataaacta aatatattag tatatgaatc tatacttgaa cataaataac
     5341 ctttatgata tgatgttgat aataatatta tgagaggagt gccttgatgt cggagttgta
     5401 taatggtaac caacaattaa atagttggag acacatatat tctgtataat cagaaatttt
     5461 aagtgtattt ttaatacatt taatttgtgt gtcttattct gcctttatag ataactgaca
     5521 tatgacaaca aatagtattt aaaatatata ttactttgtt aaattatggt gtagtaggtt
     5581 ttaatctgct acacttttat taattttgta tagtattatt ttgataacta tgttgaaata
     5641 gagagcatta acttttctag tccacaggag ttttctgttt ttgtgctgtt aaatataagc
     5701 atagaaaaag gcagatatat acctgtggat ttttttatat aaattatgaa atatggaggc
     5761 gattaaaatg agcataattg aacttaatga actgactaaa tcttatagaa gatttgagaa
     5821 aaaggcagga tttataggga gtgtaaagtc tttatttaat aggaaatata cagaaaaaac
     5881 agctatatca tcatttgatt taaagataga agaaggagaa tttgttggat taataggtca
     5941 aaatggagct ggaaaaacta ctcttattaa gatgttaact ggtattattg caccatcttc
     6001 tggagaaata tctgttatgg gttattaccc taataaatta gaaaataatt ttaaaaaaca
     6061 atatgctatt gttatgggtc aaaaaagtca actattcttt gaattgacac cagcagatac
     6121 gtttctttta tttaaagaat tatatgatat atctaatgaa gaatataaaa aaaatttgga
     6181 ttactttatc gaattatttg aggtatctga atatttaaat gttcaagtta ggacactttc
     6241 cctaggagaa agaatgaaaa tggaactaat agtagccctt ctacataatc ccaaaatatt
     6301 atttttggat gaaccaacta taggtttaga tgctgtagcc caaaaacaaa ttaggtattt
     6361 tctaaaagag gtaaatgaaa caaaaggaac tactattatt cttacttctc attatatgga
     6421 agatattaag agtctctgta gtagaagtat tgttgtagaa aatagccgta aaatatatga
     6481 tggctctaca gaggaactat ttaatcattt tcaaaaatat aaaaaaataa cagttagttt
     6541 ttccaatgaa actaacattg tattttcaaa agattgtaaa gttgttgaac aaacaaatca
     6601 taagacctca gtagttgtgc caaaagaaag aggaaatgaa acgattaaat ggatttttga
     6661 tagatatgat gttaaagatg taatgattga agaagaagat atagttaata ttgtagagag
     6721 aatatataag aaaggaagtg atgagtatta tgagcaacta taatgaagca agttcaaatt
     6781 cttcaatgtt ttataaattt aaacagagta ttagaaggta ttatgaagta gccaaaatta
     6841 actttaaagt gcaacttatc tggagatttg atgtggtagt taatatgatg tttacgattg
     6901 taaaaatttt atttgcttat attttatgga aagcaatttt tggcgaaaat aaaatagtct
     6961 ctggttttac atttaactct atgttgtctt actatataat aagctcattt ttatcaggta
     7021 ttgatatgtc gaagagtacc agtgaagaga tatgtaatcg agtaaaatta ggcacatttt
     7081 caaagtacat gattattcca attaatgttc aaaattattt tattgctaaa aattttggaa
     7141 tgacatgttt ttattttgta tttaatatga tttctgcatt tgtatggatt tttatattta
     7201 aaataaattt tgcctttaca tcaaatccaa ttcaaatatt aatttcaatt tttatgattt
     7261 ttctaggact tatttttatg atgaaactcc acttctttat tgggattttg tcatttaaat
     7321 ttcttgagat tagttttttt agaatgataa tagaaaatat tgttgaattt attacaggaa
     7381 caatgatacc acttgtgctt ttaccagaaa ctatagtaaa agttatgaag gtatttccat
     7441 tttattatac aacatatttg ccatctatgt tactaatagg tagaaacagc aatgaagcaa
     7501 tacaaggatt aattatttta gcattatggg ttttattctt ttctgtagta aataaagtta
     7561 tgtataaaag aatgagaaca ttatttgatg gggtgggtat atgatgaaaa aaaatttgaa
     7621 aataatattt atgttattaa aaatgaaatt atcaaagatg atggtattta gatttgattt
     7681 ttttggagca ttttttgtag atagttcatt atttatatta caacttctaa tgtttaatag
     7741 tatatattct catgtagact caataggggg atggcaacaa ggagagatgt taatatttat
     7801 aggaactttc tcattaataa atgcgataaa tatgacgatt ttcttttttg gtatttatga
     7861 tattccacga aaaattcagg aaggagaatt agactactat attacaaaac caatagaccc
     7921 actatttagg ttaacatttg aaaatattaa tattggttca tcaccattaa ttttagcaag
     7981 tatacttatt gttttatatg gaatctctga attaaactca gagataactt tagtcataat
     8041 aataatatat attttcatgg tgctattgat gacattactt ttttatgatg tatgtattat
     8101 acttagaaca gtttcatttt ttgttatatc atcttctgcg ataatgagat tagaagataa
     8161 tttattgcca atgaatatga aaattcctgg tgtaatatat gaaggtgttt ttaaagtatt
     8221 attctattta atcttaccat atggaattat gtccacaatt ccaactcaaa ttttggctgg
     8281 aacaataact attaatggat taatatattc aattttaatt gtattttcgt ttacattgtt
     8341 tatgtggaga ttttggaagt taggtctgag acattataaa agtgcaagta gttaataaat
     8401 tggcgaaaat agacaatata attatatata aatacgtttc acatgacact agactatgta
     8461 aacgagtatt tacactaaag gcattgaaag ctataaaatg attaaagtaa ggatttaaaa
     8521 gttactttag tataaatata attgtgtaaa aaagcaagat taattaaaac tatatccaaa
     8581 taattagata taatttttat gcagaaagga ggtctgtaaa tgtctaattg tttggaatat
     8641 attttaaaaa taattaatgt acagaaaaat aaacaaaatg agtgatgtat attattcaga
     8701 aaatcatgaa caagataatc tttatgagca agataattta ctggcacaaa gatttaattt
     8761 atttactcta ttgaagtttg catttcctac tatttttatg atgattttta tgggattgta
     8821 tacaatcgtc gatactatat ttgtatcaag atttattaat acaaatgctc tatcagcaat
     8881 taatattgta tgtccaatta ttaatcttat agttggaatt ggaactatgc ttgccactgg
     8941 aggaagtgct attgtagcac gtaagatggg aaatggtgat attgagggag caaataaagc
     9001 tttctcttta atcgtattat caggagttgt aattggggta ataattactg gtataggtat
     9061 tgtatttatg gattatatca ttatatggtt aggagcaagt gaagttttaa ttaaatattg
     9121 tcattcatat atttttatta tcttgatttt tgcttctgcg aatatactac aagtattatt
     9181 tcaatgttta tttgtaacag ctggaaagcc tcaatttgga ttatggctag tgttaggtgc
     9241 agggtgtgct aatataattc ttgactatgt gtttattgtt ctgttacaaa tgggtattag
     9301 tggagcagca cttgcaactg gagtaggata cctaattcct accatttcag gtatggtttt
     9361 cttttcaaaa aataaagggg tacttaaatt ttgtataccc agactagata aaagaatatt
     9421 atttgaagct tgttttaatg gttcatctga aatggtgggt caactatcaa cagcagttac
     9481 tactttttta tttaatgcta tgatgatgaa attaattagt gaagatggag ttgcagctat
     9541 tacaataatt atttattctc aatttctttt aacttcgctt tatataggtt tctcaatggg
     9601 tgttgcacca ataataagtt ataattatgg aagtgaaaat aatacacagt taaatcatgt
     9661 ttttaagatt tgtatattat ttatttcagt ggcatcttta ttggtattta tcttttctat
     9721 atcatgttca ccaatcattg tagagatttt ttctcaaaga ggaagccgag tttatgaaat
     9781 tgcaaggtct ggattttata tattttcttt tagttttatt ttttgtggat ataatatttt
     9841 tacctcatct atgtttacag cattgtcaaa tggcaaggtg tctgcaatat tatcttttct
     9901 acgtacattt ggatttataa ctataggttt attgatattg ccaaatatgt taaatataaa
     9961 tgggatatgg ttagcagtac caagtgctga aattttaact ttatttttaa ccgttttttg
    10021 tatatgtaag cataagaata gatataaata tatgtagata ttaaataaat agtttaggta
    10081 gatattttat gttttaataa gtaattcaat tagtggtaga tagatactat tgaaaattaa
    10141 agttataatt gatataaaga attaataaaa ataacatata aaagtttaaa aggggagttg
    10201 aacttaaagt ttgattagaa aaagtcgatt ttaagacaac tccttttatt ttactattgt
    10261 attaatctgt atctgtaagt gtattagtct aatattataa actttggatg aaattaattt
    10321 tctataggtt ttaatgtatc atatacttta ttttaaggaa acgtatctta attttcatag
    10381 tgattgaatt tgtatattag agatgttact attagtaatg taaaagcaag agtagtgaat
    10441 ataaaaaaac aagatagtga tactgcaaga ttagaatata ataaattttt atggagagat
    10501 ttcaatatgg atacatattt taataaaaaa atattacttg ttgatgatga aaaagatata
    10561 gtagatttaa ttgaagaagt acttataaat gatggtttta aaaacattat taaagcttat
    10621 aatggtttag atgctatttc gctgtgtaag atagcatgtc cagatgttgt cattcttgat
    10681 ataatgttac cagatataga tggcatagaa gtgtgtaaaa aaattcgaga gttttcatac
    10741 tgttctattc tttttctctc atcaaaaaat gatgatattg acaaaatact aggtcttagt
    10801 agtgggggag atgactatat aacaaagcca ttcagtccaa gagaaattgt ttttcgagtt
    10861 aaagcgcaat tacgtagaca acagtatcaa agtattgtac catcagatag ttcagttatt
    10921 aagataggag atattactat tgatatagaa ggaaaccgtg tatataaaga tagaaaagag
    10981 attgagttaa ctggaaggga gtatcatctt ttaagctaca tggctcaaaa tgtaaataaa
    11041 attataggaa aagaaagact ctatgaacaa gtatggggag tatacagtag tatttgtgac
    11101 aatacaatta tggtgcatat acgacatata agagaaaaaa ttgaagataa cccctcaaat
    11161 cctaaaatac ttataacagt taaaggtcta ggatataaac ttgtgaatag aatcgattag
    11221 aatagatctt agtatcaatg aaggtgtctc aaattcaatt tgttagttaa tgagacattc
    11281 ttttttgtgt gaaatcaaat gtatttttgt tatatcaata atgaagaaga ggcttatctc
    11341 tattttgaga tagcctcatt aaatttatac cgtggtaatg cactttatgc tctaataaat
    11401 atttattttt tagtttactt gcagtgaaac attaactagg agattaaaat ttgcattgaa
    11461 atgctaatta aacaatatcg catattgtat ataaacctac actaattgtt tttctatatt
    11521 aaatactttg tcaatccagc ctttataaaa tttttcttca tgggaaacta gaattatact
    11581 tcctctaaac tgtttcaaag cattttgtaa agcatccttt gtttctgcat caaagtggtt
    11641 agttggctca tctaaaatca aaaaattaca agggaataac atcatacaac ataattttac
    11701 cttagattgt tcaccaccac ttaatgtaga tacactcctt gaaacatgtt cttcctttac
    11761 gccacatctg gctagatgac gtctaatctc ttttgtattc aatttcggat atttatctgc
    11821 tactatttga agcggtgttt tagtaggatt ttcccatttt aaatcttgct cataataagc
    11881 aagtttcact tgttcagaaa actggaaatc tccagaaata caaggaatat ctttaactaa
    11941 tgtttttaac aaagtagatt taccaattcc attaaaaccc gttataacta ttttttgacc
    12001 cccatcaaca gagaaattta attttggaag caaagaatag tagtagccaa cttcaagatt
    12061 tgttactgta agagcatttt gagcagatat ttcaatttct gaaaatttta tatttggttt
    12121 tcctgtaaaa ccaggaggag ctattctttc tattttatcc aattgttttt gtcttcctct
    12181 tgcaattttt gaatttactc cagctttgtt tttacgtata aatgcctctt ctttttctat
    12241 tttcttttgt tgtgattgat atcttctaat ataatcctct cttaaatgta atttttgttt
    12301 aaggaactct gaatattttc catgatattt cttaatcata ccaaattcta tatcaagaat
    12361 acctgtagaa attttctcta aaaagtcaaa atcgtgagaa actacaataa atgctccact
    12421 aaatgtattt aaataatttg agagccattc aacgtgttct ttatctaaaa agtttgttgg
    12481 ttcgtctaat aataaaacct catggttaga aagtagcaat tttgctaaaa ttacctttgc
    12541 cctttgccca ccgctaagct ccccaacaac acgattcatt cctattgaat ctaatccaag
    12601 accatttgct attttattta cttcattatc tatagaatag aaattatttg ctattaattg
    12661 ttcctgataa tctgatgctt tgattagatg ttgctcattt ccagatatag cactttcttg
    12721 atagagtaaa ttcatctcct tttctatttt ataaagttct tcaaatgcag tgtgtaaata
    12781 gagtgatatt gttgtatctc tattgatttc tgcatattgg tctaaatggc ctatattgat
    12841 attaggttgc cacttgattt ctcctgaatc tggaataact tctcccaata aaattttaat
    12901 taatgtactt ttgcctgtac cattttggcc aactacacct atatgttcac ctttgaataa
    12961 atcaaagtta gctttctcat acagtgattt atccataaaa cattgtgata aattagttac
    13021 ttttaataaa ctcataattc aaactccttt tcttttatta aaaaatttat ggaaataaaa
    13081 aaagcagagg aatgacatta taaaatgccg acctctgctt ttggaaaaac aaaaggtcat
    13141 agacaagcat tgttgtctat gaccagaaaa tctatattat ctatcggcaa ataggtaatt
    13201 ttaaataagc atagcccaaa aactacacta aacctatatt tgccgatgaa gatagaaagc
    13261 tttaagcttt cagattaacc tctacacaac gcttcatcgt atacatttgt gtagagttaa
    13321 gttttctaac aagtttaact aattctatat aaatcataat tattcacatc ctaatcttag
    13381 tattaattct agtttatcta tatttaaatt gtacttttgt actttgtata ttgccttatt
    13441 tacttaaaat atattttatt aattatagct taaatcatgt tatcataata cttagttata
    13501 gtcaataaga aagttatatt tgctacataa cctattaatt tagtaaatct atcattacaa
    13561 agttatttga agactcacca ccaataaaat tttataatct attaaaaaat taagattacg
    13621 agatttataa ttttgataca ggtatactat ctttattaaa tattgcaaca tgtagaagta
    13681 gatggataat attattaaat tttcaatgat atgctaatgt acatatataa ttattagaaa
    13741 taaaaatata atagtatgaa agtaactgat ataataacta aatgattaaa catatagtaa
    13801 aagtacttca taaattatgg agtatctttt attgtcgcaa aaataagcaa tatattatac
    13861 aaaataaaaa cattaattca acttaaataa ttttaagtgt aatatgtatt ttgattaaat
    13921 aagctaaaat tctaagaaaa aataatatat ttgtattaag ttttattgaa ataattaaaa
    13981 ttatttactt aatgtaaatt gttagcttaa attatattaa ataattaagg cggtgagtgg
    14041 gtctggatga gatagattta aaaataatta attctctaag aaagaatggt aggtttcaac
    14101 ttctgaaata agcagaaaaa ttaatttatc aataccagca gtctcagagc atataaggaa
    14161 aattgagcaa ttaaatttaa ttcaaaagta cactattcaa attaatcagg aaaaaataaa
    14221 atataagctt ttggcttttg tatttatcaa tacggattta tctaaaagta tggaagaatt
    14281 taagaaaact atattggaat atgatactgc attagaatgt catcatattt aaatctaata
    14341 agggagttta atttaaaaga aaaaataatc gcttttattt gtgtgtcagc attgctgatt
    14401 ggaaaaagtt gtgttttaaa aaatcgtaaa gctactacat atcatttgaa aaatagtaaa
    14461 agacaaagac agttaagtga gtttgatgta aatgtagtta atgaaccaac tgttgtaaat
    14521 caaaacatta taacctcata ttatacagaa acagctccac atgtagcttt taagctttta
    14581 gaaatgttga tatctaaaaa acaactggat gaagttaaat tagctatggg atttaaactg
    14641 taatagttta gagcttttcc aagtaatcag aaccccagtc gcacatggaa tctaaaattg
    14701 gaataatact ctttccaaaa tcagatagtg agtattctac ttttggagga acaacaggat
    14761 aaaccactct tatgattaaa ccatctgatt ctaattcacg taattgttga gttaacattt
    14821 taggtgttgc cttagggatt aattttttta attcattgaa cctcaatata gtgtctttaa
    14881 gatgccaaag tataagtgtc ttatatttac caccaatcaa tgcaagtgtt gcttctattg
    14941 ggcaactgta attatctaaa cattttttca tttttggact cctttattta ttttaaagta
    15001 tctttttagg tactatatta caaaaaagtg cattattgta atatattacc atagtgctaa
    15061 aattatagca taggttaaat aaatcatcaa cttagtctaa taaaacaata ggaggtaaat
    15121 aaatgaattt cgttgaactt gcaaaaaaaa gatattcttg ccgtaattat caagatagaa
    15181 aggttgaaaa agaaaaactt gataaggttt tagatgttgc aagaatagct ccaactggtg
    15241 gtaatcgtca acctcaaaga ttgattgtta ttcaggaaaa agagggtcta aataaacttt
    15301 ccaaggctgc caatatatat gatgctccat tagcaattct tgtgtgtgga gataaagaga
    15361 aggtttggac aagacctttt gatgggaagc aacttacaga tattgataca agtatagtta
    15421 cagaccatat gatgctacaa gcaactgaac ttggattggc aagtgtttgg gtatgctatt
    15481 ttaatccaga tataattaga gaagagttta gtttgccaga taatctagaa ccaataaata
    15541 ttttattgat gggatatgaa tctaaggtag cagatagccc agatagacat gaaaaaactc
    15601 gtgttccttt aagtgaaatt gtttcttatg aaattcttta attataaaat taagttattc
    15661 ataggttaaa tgtaacaaag tgtttattat aaataaaact caaaataaat aatatcctta
    15721 gataaataat atctatataa ttaattttag tgaagtatat ctagtttaac tagaatatat
    15781 acttcactaa tttatttgtt caaaatattt gtgaggattt taatatatta actaaaatat
    15841 atcaattgaa ttaattttta aatctggaaa agcacttgaa atatagtatt ttatgtcatt
    15901 taaatggtct tgaatttgtt tttctgatat tttatcaggt ccatatacaa aatacataat
    15961 atttttagta tcttttgtta tagctgttcg attatcaggt ccattaagaa tgctagataa
    16021 tataccaata ttatccgata aaaataaatc atcttttgtc aaaatctgtt ctttagcacc
    16081 tataccataa aaatgttcac ttccatttgc taagtctatt ttcaaaggta attctatttt
    16141 atcaaggtca tgacctgctg ttagaagaag atttttcaat tctgctaaaa acattgactc
    16201 aattgttaca cctacatctg ggataccttt tgattttaat agaatagatt ctaattgaag
    16261 caatacaggg taagttttct tgaatttttt gtaatacttt atataacttg aaacaggctc
    16321 tgttttaatt ttttctttac gattgtattc tggatgtttt tctataatat ttttaattgt
    16381 agagttttta agaattaaaa aattttcttt attaggtttt gaatgtgtaa tatttataac
    16441 cataactcca aatttaatat tgggataaat ttctttcact ttatgtgata tttctaacat
    16501 aatatagact cctttttatt ttttgtttta tgatataatc ttagcaagtt aaaagtagat
    16561 tttgtagttc catttttata gtaattttat agaaccactt ttggaggtat tagaatgtgg
    16621 attacgatta atagaaatag taatatatca ttatcaagac aaatttattg tgagataaaa
    16681 gatatgattc tgaatggaag cttaaagttt gagcaaaaat tgccatcatc taggacttta
    16741 tcaaaagaac tatctgtatc tcgtaataca gttttagatg catataatca attaattgca
    16801 gaaggatatt tggaaacaag gaatggatat ggaacaattg tagctaaagg aatatcaggg
    16861 cataaagttg attttaagtt aaattatatt tttagagatg aaaaagattt acatactaat
    16921 aaacaaaaaa attatataga ttttcgttca ggagttccag aattaaaact atttccacgc
    16981 aaagaacttt caaagctata taaacaaata ctgtatgatt tatctgattc ggatttcaga
    17041 tatggaagta cagctggtgt atgggtttta agagcggaaa tatctaagta tttatttcgt
    17101 actagaggaa ttagatgtaa tcccaaaaac attatgattg tttctggttc aacacaaggt
    17161 ttatctttaa tttcacagct tttatacaaa agtaataaaa aggttgctgt agaagaccct
    17221 attcataaag gcttattaaa ggttatttca tctattggat attcagttgt tggagttaaa
    17281 gtagatgata agggaataaa taccaactta ataaaatcaa taaaggggat ttcttttgtt
    17341 tatactacac cttctcatca atacccatta ggagggattt tacctattca aagaagactg
    17401 gagcttatta aatatgcaac ggagaatggt tactatataa ttgaagatga ttatgatagt
    17461 gaatttagat atgagggtca accaattagt tctctttatg aacttaaccc aaataaagta
    17521 atttacatag gttcttttag taaaatatta tctccagcca ttcgtgttgg atttatatta
    17581 ttaccagaca atattttaga aagctataaa accttaaaaa tgtactctga tgttcataca
    17641 gaaacaatat tacaacatgt attagctgaa tttattggaa atggaggttt agagaagtac
    17701 atatttagaa tgaagaagtt gtataataga aaacgtaagt acctcataaa agttttaaac
    17761 acggaattta aaaatgaatt taaaataaaa ggtgaagcag cagggcttca tatagttgct
    17821 catttctata atgttaaatt tacggaaagt ttaattcata aaatttttga agcaggcata
    17881 aaagtttatc ctatacaaca atatgcaatt gagaaaatat tagaatatga ccatgaaatt
    17941 atactaggtt atgctcatct tagttttgat gaaattgaaa aaggtgtaaa aatactcagc
    18001 aaaataatac atataaatca aggtacatag ataaaacata tagcaatcta catataatag
    18061 atgcaatgaa gtttaaactt taaaagaaat atatattaat atttttgtat aaaaatacct
    18121 gatattgtgt tatcgatact ttgttgctat acactaaatt aagatagcaa tttatattaa
    18181 gaaaaaactt tttgcatagg ttataatact taaaaggaga ggatagagtt gaaaacaaat
    18241 acagatgtta ttatggagat aattgattat atagaagaaa atcttacaga aaatctaaat
    18301 ttagataaaa tagctgatat tgctaattat tcaaaatacc atttacacag aatgtttaca
    18361 aacattgtag gatgtactat tcatcaatac atccagagga ggagactcac tgaagcagct
    18421 agacagctta tatttacaga caaatatatt atagacatag ctattacagc aggatattct
    18481 acacatcaat cttttacact agcatttaga aatttatata aagaatctcc acaagtatat
    18541 agaaataaag atgaatttta tcctattcaa cagagatttg ttttaaatct aaatcatcag
    18601 attcaaagcg aaaaatatat ttcttatgca aatatgaatt gtaaacaaag aatagatgaa
    18661 attaattctt atcttaactt taatattaat tgtgaggtga aagtagcatg agtttagtac
    18721 cacatgtaat tgaacaaaca agtcaagggg aaaggtctta tgatatatat tcaaaattat
    18781 taaaagatag aattatattt ataggagaag aaattaatga tgctattgca agtttagtag
    18841 tagctcaatt actgttttta gaatcagaag acccagattc agatataatt atatatataa
    18901 atagccctgg tggctctgtt acagcagggt ttgctatata tgatactatg aattatgtca
    18961 gatgtgatgt atcgactatt tgtattggta tggctgcaag tatgagtgct tttttacttg
    19021 caggaggaac acatggaaaa agatatgctt tacctaatgc agagattatg attcaccagc
    19081 caatgggagg agctaaaggt caagcaacag atgtaaaaat agctgtagat aatatattga
    19141 aaataaaaga acgattagat agaatttttt ctgaaaatac aggtaaatca atagaagata
    19201 ttagaagaga tacagataga gataatttta tgactgcact agaagctaaa gagtatggac
    19261 tgattgatta tataatgaat aggaatgaat aaagtatcat attaaaatat ctgttttata
    19321 aatatatata gaatattaaa taagagtgtc tcaaagtgaa ctttttagtt tatgggatgc
    19381 tcttttttgt atgaaattaa atatagtttt attatttcaa taactagtat caaatttcaa
    19441 gtttaataaa ttctaccata aaaatacata aaagataagg ttttttagta actttctgtc
    19501 gtcaaaagtt tttataaatt taataacaaa acaagagaaa ataccatata ttacttatgt
    19561 ctgcaatata tagaagacaa aggagttgta cattatgatt acaataagtt tgtgcatgat
    19621 tgttaaaaat gaggaagaag ttataggcag atgcttagaa tgtgtaaagg atatagtaga
    19681 cgaaattata attgtagata ctggttctac agattccaca aaagaaatag tctcaaaata
    19741 tacagacatg gtgtacgatt tcgaatggat agatgatttc tctgctgcaa gaaatttttc
    19801 attttctaaa gcttctaaag actatacgat gtggcttgat gcagatgaca taattttaga
    19861 agctgataga gaaaaattat taaagattaa agaaagcttg gatacttcca ttgatattgt
    19921 tatggcaaaa tacaatgtat cctttgatga aaatggtagc ccaactctct cgtattatag
    19981 agaacgattg tttaaaagaa gttctaatca taaatgggtt gaccctattc atgaagtagt
    20041 acctctttct ggagaggtat tttattctga cattgcaata tctcataaaa agcttcatag
    20101 acaagaccct ctaagaaatc ttagaatttt tgaaaaaatg atttcagaag gaaaagtatt
    20161 ggagccaaga caccaatttt attactctag agagttgtac tataatgcta agtataaaga
    20221 agcaatagaa ggttttacta agtttttaga ctcatcaaga ggatggattg aggattgtat
    20281 cagtgcttgc agagatttag ccacatgtta ttacttaatt aatgatgaaa agagtgcctt
    20341 atattctttg tttagaagtt ttgaatttga tgagccaaga gcagaaattt gttgtgacat
    20401 aggaaagcat atgtttgata gacaaaaata taaagaagct attttttggt ataaggtagc
    20461 actaacaaga gataagaatg atactaatgg aggttttaag tcaaatgatt gttatggata
    20521 tataccatat atacaattaa gtgtctgtta tgacaggcta ggagaatcaa ataaagctat
    20581 ttattatcat gaaaaaacaa aagaaatcaa acctaatgat agtgctgttt tgcacaatga
    20641 aaattatttt aataaattta aaaatagttg ataggtcaca ataatactaa atttgacata
    20701 ttatatatag agcttagaag ctcaaatata tcaggaggtg cttttaataa tgagtagaaa
    20761 taaatatttt ggaccatttg atgataatga ttacaacaat ggctatgata aatacgatga
    20821 ttgtaacagt ggtcgtgatg attataatag ctgtgattgt catcattgct gtccgccatc
    20881 atgtgtaggt ccaacaggtc caatgggtcc aagaggtaga acaggcccaa caggcccaac
    20941 gggtccaaca ggaccaggag taggtgcaac gggtccaaca ggtccaacag gcccaacagg
    21001 tccaacagga aatacaggag gaactggaag aggaggccca acaggtccaa caggtccgac
    21061 gggtccaaca ggtccaacag gcccaatagg atttggaata acaggtccaa caggcgcaac
    21121 tggagcaaca ggtgcaaccg gagcagatgg agtaacaggc ccaacaggcc caaccggagc
    21181 aaccggagca aatggaataa caggtccaac agg
//
LOCUS       DAMKOJ010000247        20866 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.065, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000247 DAMKOJ010000000
VERSION     DAMKOJ010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20866
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.065"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            complement(90..839)
                     /locus_tag="PC592_003798"
     CDS             complement(90..839)
                     /locus_tag="PC592_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF4057680.1"
                     /translation="MKNKKIIRKFTVLLAALVIMCGFSVTAYAGGGDESDDTPTPVTE
                     ETPAPETEPEETTGGYEPQPLTPDGNMSLVDDITGEASGDKQFITVVTKSGNYFYIII
                     DRAEDGENTVHFLNQVDEADLTALMEDGQTEAPVCSCTDKCVAGSVNTACPVCSVNMS
                     ECAGVEAEPEPEETEQPPEEEKGGGMGILLVVLLVAAAGGGAFYYFKILKPKKDAAKG
                     SSSLDDLDFDEDDEETEVVETEQTEQEDDNL"
     gene            complement(829..1095)
                     /locus_tag="PC592_003799"
     CDS             complement(829..1095)
                     /locus_tag="PC592_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HDF4057681.1"
                     /translation="MANTKLDRIERDIEKTRAKILEQQKKLKDLEAQKVEEENAQIVQ
                     MVKAVHLDGTQLAAFLSAYASGEITLPQPEATYPAEQEDNDNEE"
     gene            complement(1102..1362)
                     /locus_tag="PC592_003800"
                     /pseudo
     CDS             complement(1102..1362)
                     /locus_tag="PC592_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604475.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
     gene            complement(1485..3386)
                     /locus_tag="PC592_003801"
     CDS             complement(1485..3386)
                     /locus_tag="PC592_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4057682.1"
                     /translation="MYYTQEQIDRANQADLVLFLQSQGEPLERAGQEYRWKRHDSLTV
                     RGNKWYRHSQSKGGGPIDFVMEFFGKSFTEAVELLTGEKGAAPPPDRPSSAPLSDFRL
                     PPRSPDNRTARNYLTAARRIDEDVTGFFFASGDIYEDAAHHNAVFVGRDEDGIPRYAH
                     SKGTAGNFRLDVKGSDKAFNFCYRGEGERVFVFEAPVDLLSFLCLFKKDWQKQSYLSL
                     GGVGEKALLRFLSDRPNIKTVYLCLDSDEAGNDACSRLVKLMPEGYTVHRLIPLFKDW
                     NEVLQHRAEITDGKYLREAVYGLKEPPQEETVEIIRMSEVDTQTVEWLWEPYIPFGKV
                     TIVQGNPGEGKTTFALRLAAACTNRKPFPHMAVHEPFNVIYQTAEDGLGDTIKPRLME
                     AEADLDRILVIDESKQGLSLSDERIERAIRQTGARLIILDPIQAYVGEKTDMNKANEI
                     RPMFRRLAEIAERTGCAVILIGHLNKAAGGQSAYRGLGSIDFRAAARSVLLIGRVKRE
                     PNVRVIVHDKSSLAPEGKPIAFCLDPETGFSWIGEYDITADELLSGAGGNTATKTEQA
                     ERLILDLLADGKELASEDLVKAAAEAGISERTVQNAKRNMGGVLGARRVGGQWYNFIK
                     KKQPPEPAS"
     gene            complement(3401..4915)
                     /locus_tag="PC592_003802"
     CDS             complement(3401..4915)
                     /locus_tag="PC592_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005922895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HDF4057683.1"
                     /translation="MIPIAIYHCNISIVSRGKGKSAVAAAAYRSGEKLTNEWDGMTHD
                     YTRKGGVVHTEIMLPPHAPPSFSDRSTLWNSVELYEKAGNAQLAREIDAALPIELSRE
                     EQIRLVREYCSSQFVSRGMCVDYAIHDTGKGNPHCHIMLTMRPLDERGAWAAKSQKEY
                     DLDENGERIRLPSGRYKTHKVDLTGWNDKGNALLWRKAWADISNAYLERAGSPERIDH
                     RSNAERGIGEIPTVHMGVAACQMEKKGIATEKGELNRNIQKANRLIREIRAQIGKLKE
                     WIADLFKAWETAPEQPQQSPGLANLLMKYLSVQREKSRKYSQRWQQQHTADELKTIAA
                     AVNYLTEHGISTLDELDAALSSVSEQADTIRAGMKTAEERMKKLQKLIEYGKNYTEYK
                     PVHDELKKLQNGWTNKRDKYEEAHRAELTLWNAASRYLHANLPKGTKTLPIAEWEQEY
                     ADLKTQRDSDYAKLKDTRADVSELQKIRKCVDIALRADQPEQTQTRTKRHDIDR"
     gene            complement(5155..5460)
                     /locus_tag="PC592_003803"
     CDS             complement(5155..5460)
                     /locus_tag="PC592_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HDF4057684.1"
                     /translation="MTTHDETERKKREELQAEIEDGKKKIRQLENREKVLRQKLSQEE
                     RRTRSHRLIVRGAVFESIVPEAKTMTDEEAAAFLRLALTSEEARGYLKKRTEGGKSE"
     gene            complement(5582..6415)
                     /locus_tag="PC592_003804"
     CDS             complement(5582..6415)
                     /locus_tag="PC592_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF4057685.1"
                     /translation="MNNNLSRFADSKVYFQCPICTKSMDIQGNSLICRHGHCFDISRY
                     GYVNLLLKSSPKTNYSKRSFDNRHQILEYGMYDVVLEKIIQFISDTPSIRNILDVGCG
                     EGFYARQIQQRTERNIFAFDLSREAIQIASKKDKRKAVKWFVTDLSKIPLKDGSMDCI
                     LDIFSPAHYKEFQRLLSPNGYVVKVIPTKNHLREIRTKVQAHLKNPDYSNESVVEYFE
                     KYLKTISRETVSATVQLSSEQRMSFIEMTPLLFCVEKDCVDWRTLTHLTIEADVLIGM
                     Y"
     gene            complement(6584..6886)
                     /locus_tag="PC592_003805"
     CDS             complement(6584..6886)
                     /locus_tag="PC592_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057686.1"
                     /translation="MRTGLTKQEKTTDIWFDEKDPLIHIRTHNTALKKRLLAYSRRYP
                     AICQQTDADPETGCMEFDIEKGRFSFRLTAPYSEERRAVCQREQRRRQAEIELKCS"
     gene            complement(7021..7236)
                     /locus_tag="PC592_003806"
     CDS             complement(7021..7236)
                     /locus_tag="PC592_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF4057687.1"
                     /translation="MTEQNGTPTAPRNPDSIITTQRNGQTIVAELFFNHSSTETFRDK
                     LLKTILADSSCLSASDGQEPEKSEILR"
     gene            complement(7315..8703)
                     /locus_tag="PC592_003807"
                     /pseudo
     CDS             complement(7315..8703)
                     /locus_tag="PC592_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147943.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(8703..9119)
                     /locus_tag="PC592_003808"
                     /pseudo
     CDS             complement(8703..9119)
                     /locus_tag="PC592_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605636.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
     gene            complement(9232..9618)
                     /locus_tag="PC592_003809"
     CDS             complement(9232..9618)
                     /locus_tag="PC592_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009259636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP protein"
                     /protein_id="HDF4057688.1"
                     /translation="MSDNLPRMDYRQHRRARRLVHECCNYDEGNCLLLDDGEPCVCVQ
                     SISLSLMCRWFRVAVLPLDGELSAALLYRGSRKRCAVCGAAFVPKSNRGKYCPDCAGR
                     MKKIRAAERKRKQRQRCHALEPFKPA"
     gene            complement(9608..11233)
                     /locus_tag="PC592_003810"
     CDS             complement(9608..11233)
                     /locus_tag="PC592_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF4057689.1"
                     /translation="MATLKHINSKNADYGAAEQYLLFEHDEFTMKPVLDETGRLIPRE
                     DYRLSTLNCGGEDFAVACMRANLRYEKNQRREDVKSHHYIISFDPRDGPDNGLTVDRA
                     QALGEQFCKEHFPGHQALVCTHPDGHNHSGNIHVHIVINSLRIEEVPFLPYMDRPADT
                     KAGCKHRCTDAALRYFKSEVMEMCHREGLYQIDLLNGSKNRITDREYWAQKKGQAALD
                     KQNAPMIADGITPRQTKFETNKEKLRQTIRKALATAASFDEFSSLLLREGVTVKESRG
                     RLSYLTPDRTKPITARKLGDDFDRTAVLAVLEQNAARAIEKAAAIPEYPWQEKRGIQP
                     AKAPQTAPKQDGVQRLVDIEQKMAEGKGRGYERWAKIHNLKQAAKTLSVYQQYGFTSP
                     EQLEAAVDTAYAEMRQTSGELKALETKLQGKKELQRQVLAYAQTKPARDGLKAQKSEK
                     ARAAYRQAHESDFIIADAAARYFKAHGITKLPARKALQAEIEQLISEKDGLYNTYHEQ
                     KQRFKELQTVKRNINQILRRDEPHRRKEQSHER"
     gene            complement(11205..11603)
                     /gene="mobC"
                     /locus_tag="PC592_003811"
     CDS             complement(11205..11603)
                     /gene="mobC"
                     /locus_tag="PC592_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF4057690.1"
                     /translation="MRKKYNTPHRSRVVKTRLTEDEYADFTARLAPYGISQSEFLRQA
                     IRRTTIRPVLHVSSVNDELLSAVGKLAAEYGRIGGNLNQIARYLNEYGAPYHALSGEV
                     RAAIADLAALKYEVLKKVGDAVGNTQTYQL"
     gene            12024..13244
                     /gene="tet(40)"
                     /locus_tag="PC592_003812"
     CDS             12024..13244
                     /gene="tet(40)"
                     /locus_tag="PC592_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009247026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(40)"
                     /protein_id="HDF4057691.1"
                     /translation="MFAKNSKAYSVYLLFRFVFSLAVSMSTVLSIVYHLEVVQLDAFQ
                     LVLVGTVLETSCFLFEIPTGVVADLYSRRRSVLIGMFLYGLGFLMEGALPWFAPVLLA
                     QVVWGCGDTFITGALEAWIASEEEDKPIDKVFLRGSQMGQIGGVLGVVLGTLLGNINL
                     QMPVILGGSLCLLLGLVLVRIMPETNFSPAIEERQGLLKDFVCLFKLNLGFVKGAPVL
                     LALLAITLCGGLASEGFDRLSTAHFLDDTVIPVIGPLNSVTWFGVISLIGSGLGILAS
                     QLLIARMEKKGTVSRTSVVMSTSAGYILCLVLFAVGRSFWFMLLVFLLAGLMRTIKEP
                     VLAAWMNDHVDEKMRATVFSTSGQLDSFGQIIGGPIVGLVAQQVSIPWGLVCTAFLLL
                     PALFLVPVAGKKRD"
     gene            complement(13387..13527)
                     /locus_tag="PC592_003813"
     CDS             complement(13387..13527)
                     /locus_tag="PC592_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057692.1"
                     /translation="MAFFNSAVNVLQTLVIALGAGLGIWGVINLLEGYGNDNPGANAH
                     VR"
     gene            complement(13769..14599)
                     /locus_tag="PC592_003814"
                     /pseudo
     CDS             complement(13769..14599)
                     /locus_tag="PC592_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037036.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            complement(14638..14805)
                     /locus_tag="PC592_003815"
     CDS             complement(14638..14805)
                     /locus_tag="PC592_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF4057693.1"
                     /translation="MNTNTIQTTAQHTQPCYRKTIDKTTYVVRVHFSENAKETMEDKI
                     KRLLREEVAKM"
     gene            complement(15059..16408)
                     /locus_tag="PC592_003816"
     CDS             complement(15059..16408)
                     /locus_tag="PC592_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006573536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HDF4057694.1"
                     /translation="MNNELQNTVDEVRNSLEQSQKGKVYNTAANYKRVLQCDPLLKGA
                     IRKNLLTERIDIVKPLGWYRDSTTLTDVDIKYLVLYFEENYGLTVEKKIVDAITVIAN
                     ENRYHPVCDFLNSLKWDGQERIRHCLHHFLGSEENEYTYEALKLFMLGAISRVFKPGC
                     KFEVMLCLVGGQGAGKSTFFRLLAVNDDWFSDDLKKLDDDNVYRKMQGHWIIEMSEMI
                     ATANAKSIEEIKSFLSRQKETYKIPYETHPADRKRQCVFGGSSNTLDFLPLDRTGNRR
                     FLPVMVCPEQAEVHILEDEATSREYIIQMWAEAMEIYRSGNFKLKLSRSTDEFLKAHQ
                     KEFMPEDTKAGQIIDYLERYSGNTVCSKQLYREALGHDYDEPKQWELREINDIMNNAV
                     TGWKAFANPRYFPEPYRRQRGWERIPIDNEPDNNTGKFHELTEAEMQQLELPKEWLE"
     gene            complement(16341..16958)
                     /locus_tag="PC592_003817"
     CDS             complement(16341..16958)
                     /locus_tag="PC592_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009259716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF4057695.1"
                     /translation="MNVFEAVKPNISTRQAAEMYGIKVNRNGMAVCPFHNDKNPSMKV
                     DKRFHCFACQADGDVIDFVSRLCGLPCKEAAMKLADDFGISYDSRHKPTVRPHIREPT
                     AEQLYQKEEARCYRVLTDYFHLLRRWETQHAPKQPDDVWHPLFVEALQRKSHIEYLID
                     TLIDGTKEEKQALVAEQRKEVMKLEQRIAEYRGRSPKQFGAEPER"
     gene            complement(17027..18622)
                     /locus_tag="PC592_003818"
     CDS             complement(17027..18622)
                     /locus_tag="PC592_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006859284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HDF4057696.1"
                     /translation="MPIPHLNIRIVQRSKGSSAVAGAAYQAGEKLFSEYDQKNKDHRR
                     KQKEVVYTEIMLPANAPPEYADRETLWNSAEEVEKQWNSQLARRFVVALPREVPLEMC
                     PQMLQEYCEEYFVSKGMCCDIAIHDPDPPGHNPHCHIMLTMRAIDENGKWMPKSRKVY
                     DLDENGERIKLPSGRWKSHKEDTVDWNEQYHAEEWRHGWEVIQNKYLELAGSPERVDM
                     RSYARQGIDVIPTVHMGAAVSAMERKGIETNIGNLNRDIKSANSLMAAIRKTIKSLLE
                     WIADVSEATKEALAEMKEQNASPTLAGLLNEYLNVRKEERRDWSRYGQNKGSLADVQA
                     VSKAVAYLRDHNLYTLKDLDEALQEVNGRAASIRSAIKTAETRMKTITQIQKAVSVCK
                     EHKAVKDKYLKIGWKAAQAVYAETHKDALSAFDKSFRYLKKQGLDLRVDLTALQSEFD
                     TLEKSVAENNAKLSEVKAELQPLKDVRYWISKVIEPEQGEVEKKPEPKHSVTEKMKYL
                     QEQKKQLEPKSPQHKQKKQNMEL"
     gene            complement(18738..19187)
                     /locus_tag="PC592_003819"
     CDS             complement(18738..19187)
                     /locus_tag="PC592_003819"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF4057697.1"
                     /translation="MTIDELLSGEKLLSIAEKENKANLQRMCSLLFGIVDLFSFMLIV
                     LPLYPNPINGYIYSVNLFSYTDTAFFNIILYWVSYLALIVMGITKIALTQLKTERGQS
                     IITSLSLGLSILTVLYLGMAREAYAITVAFMLLLIKGILLLKYTQNS"
     gene            complement(19273..20850)
                     /locus_tag="PC592_003820"
     CDS             complement(19273..20850)
                     /locus_tag="PC592_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015520053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4057698.1"
                     /translation="MRLSRDDENYGDSVSIETQRTILQQYAKEQGLHVVGEYVDDGWS
                     GTNFERPDFQRMMDDMEAGKVNCIVTKDLSRFGREHVMMDYYLEFLFPEKRVRYIAVA
                     ENEDTEKGLSDFVPFKNLFNEWFAKDTSRKVKAAFKAKFATGQRIGAYAPIGYRKHPE
                     IKNKLIIDEETRWIVEKIFDLAIHGRGAASITRILIAEKVPTPGFINFQRDGTFANIY
                     AGAPEEKSYAWTIAQVKSIMKDETYIGHTIHYRETNISFKNKRRVRKPQSEWVRVENT
                     QEPIISEQVFRQVQEQIANRRRKCKDGTTQIFSGLVKCADCGWSLSYGENRQNSKPYG
                     HYHCSKYGQGTRQCSMHYIRYDVLYAYVLSRLQYWSGLVQHDEERLLKQLLNATDKGQ
                     AAARKKQAAELKKAEKRKAEVDTLFARTYEDWAAGRITEYNFSMLSGKYQSEQAELDE
                     KIEQLQSAIATESQNAVDAEKWIALMKECVNPTELTAELLNMLIEKIVVHEAVKGEDG
                     SREQEVEIFYRFIGKID"
BASE COUNT         4210 a         5408 c         5268 g         5980 t
ORIGIN      
        1 gccctcaaaa tatccgctgc gcttttcatt cgcgcccata acggcggcaa tcgccgcccc
       61 gacgctcggt ttttctgcaa ttacaagttt catagattat cgtcctcctg ctcggtctgt
      121 tcggtttcga ctacttccgt ttcctcgtcg tcctcgtcaa aatcaaggtc gtcaaggctg
      181 ctgctgcctt tcgccgcgtc ctttttgggc ttcaaaatct taaagtagta gaacgcgccg
      241 ccgcccgctg cggcaacaag cagcacgaca agcagaatac ccatgccgcc gcctttttct
      301 tcttccggcg gctgctcggt ttcttccggc tccggctcgg cttccacacc cgcgcactcg
      361 ctcatgttga cgctgcaaac cgggcaagcg gtgttgacgc ttccggcaac gcatttatcg
      421 gtgcagctac aaacgggggc ttcggtctgc ccgtcctcca taagggcggt taaatccgct
      481 tcgtccactt ggttaaggaa atggacggta ttttccccgt cctcggcgcg gtcaatgatg
      541 atgtaaaaat agttgccact tttggtaacg acggtgataa actgcttgtc gccggacgct
      601 tcacccgtta tatcgtccac aagggacata ttcccgtccg gggtaagggg ctgcggctca
      661 tagccgcccg tcgtttcttc cggctcggtt tccggcgcgg gggtttcctc ggttacgggg
      721 gtaggcgtgt cgtcgctttc atcgccaccg cccgcataag cggtaacaga aaagccgcac
      781 atgataacca gtgcggcaag caatacggta aactttcgga ttatcttttt attcttcatt
      841 gtcgttgtcc tcctgttcgg cggggtaagt ggcttccggc tgcggcaagg tgatttcgcc
      901 gctggcgtaa gcggagagga acgcggcaag ctgcgtcccg tcaaggtgta ccgcctttac
      961 catttgcacg atctgcgcgt tttcttcctc gactttctgc gcttcaaggt ctttcagctt
     1021 cttttgctgt tcaaggattt ttgccctcgt tttctcaata tccctttcga tacggtcaag
     1081 tttcgtgttc gccatagtca tttactcctt tccaaactgt tctttccatg aatagctgcg
     1141 ccccaatccc ttaacggttt taagataggg catagcgttt tcttccaaag tcgccgcccg
     1201 gttaaataga tcgggatagt gttctttgag atataaaatc tcttgtttct tcatgctcgg
     1261 acaaaagaaa caggacgatt tacccggctg cggcaatcct gccgctttga tttcccggat
     1321 acaatcgtcc ctgttccagc cccattcttc aatgaggggg tagggcttta tatcttcggc
     1381 gtttccccat gaagcgtttt gtcaagtgtt atttggagtt attgacgcac aatcaaggcg
     1441 aaagcgcgaa agtgcaaagc gcaaagggtc tgcactttgc gttttcagct tgcgggttcg
     1501 ggcggctgct tcttcttgat gaagttgtac cattgaccgc cgacgcgcct tgcgcccaaa
     1561 acaccgccca tgttgcgctt ggcgttctgt accgtcctct cggatattcc ggcttcggct
     1621 gcggccttta caaggtcctc gctggcaagc tctttcccgt ctgcaagcag gtcaagtatc
     1681 agccgttccg cctgttcggt cttggtggcg gtgttgccgc ccgcgccgga cagcagctcg
     1741 tcggcggtaa tgtcatactc gcctatccac gaaaagcccg tttccgggtc aaggcaaaag
     1801 gctatgggct taccctccgg cgcaagagaa gatttgtcat ggacgataac gcgcacattc
     1861 ggttcccgtt tcacgcgccc gatcagcagg acgctccttg ctgcggcgcg gaagtcgatg
     1921 gagcctaaac cccggtaggc gctctgtcct ccggcggctt tgttgaggtg tccgattagg
     1981 ataacggcgc acccggtacg ctcggcaatc tcggcaaggc ggcggaacat ggggcgtatc
     2041 tcgttggcct tgttcatgtc ggttttctcg cccacatacg cctgtatggg gtcaaggata
     2101 atcagccgcg ccccggtctg tcggatagct ctctctatgc gctcatcgga cagggaaagc
     2161 ccctgcttgc tctcgtcaat gacaagaatg cggtcaaggt ctgcttcggc ttccataagg
     2221 cggggcttga tggtgtcgcc caaaccgtcc tcggcagtct ggtaaatcac attgaacggc
     2281 tcatgcactg ccatgtgggg gaacggcttg cggttggtac aagcggcggc aaggcgtagg
     2341 gcaaaggtgg tcttgccctc gccggggttg ccctgcacaa tggttacttt cccaaagggg
     2401 atatacggct cccataacca ttcgacggtc tgcgtgtcca cctcgctcat gcggataatc
     2461 tcaacggttt cttcctgcgg cggctctttc aagccgtaga ccgcttctcg caaatacttc
     2521 ccgtctgtga tttctgcccg gtgctgcaat acctcgttcc aatccttgaa aagagggata
     2581 agccggtgga cggtgtagcc ctccggcatg agcttcacaa ggcggctgca agcgtcgttt
     2641 ccggcttcgt cgctgtcaag gcagagataa acggtcttga tgttcggacg gtcagagaga
     2701 aagcggagca gggctttttc tcccacgccg cccaatgaca ggtagctttg cttctgccaa
     2761 tcctttttga acaggcagag gaaagaaagc aggtcaacgg gggcttcaaa gacaaacact
     2821 ctttcgccct cgccccggta gcagaagtta aaggctttgt cgctgccttt cacatcaagg
     2881 cggaagtttc ccgccgttcc cttgctgtgg gcgtagcgcg gtattccgtc ctcgtcccgc
     2941 cccacaaata cggcgttgtg gtgggctgcg tcctcgtaaa tatcgccgct ggcaaagaaa
     3001 aagcccgtca catcttcatc aatgcggcgg gcggctgtga ggtagttcct cgctgttcgg
     3061 ttgtcggggc tgcggggcgg tagccggaag tcggagaggg gcgcggagct tggtctatcc
     3121 ggcggcggtg cggctccctt ttctcctgtg agaagttcaa cggcttcggt aaaactcttg
     3181 ccaaaaaact ccatgacaaa atcaatgggg ccgccgccct tgctctggct gtggcgatac
     3241 cacttgttgc cccggacggt caagctgtcg tgccgtttcc atcggtattc ctgtccggcg
     3301 cgttccagcg gttccccctg cgattgcagg aacaaaacaa ggtcggcttg gttcgcccgg
     3361 tctatctgtt cttgggtgta gtacaaaaaa ctcactcctt tcatcggtct atgtcgtgcc
     3421 gctttgtgcg ggtctgtgtc tgctccggct ggtcggcgcg gagtgcaata tccacgcatt
     3481 tgcggatttt ttgaagttcg gaaacatcgg cgcgggtatc tttcagtttg gcataatcgc
     3541 tgtccctctg tgttttgagg tcggcatatt cctgttccca ttccgcaata ggcaaggtct
     3601 ttgttccttt cggcagattt gcatggagat agcggcttgc tgcgttccat agggtcaact
     3661 cggcgcggtg ggcttcctcg tacttgtcgc gcttgtttgt ccagccgttt tgcagctttt
     3721 tcagctcatc gtgaacgggc ttgtactcgg tgtagttctt cccgtattca atcagctttt
     3781 gcagcttctt catgcgttcc tcggcggttt tcattcctgc ccggatagtg tcggcctgtt
     3841 cgctgacaga ggaaagggct gcgtccagct catcaagggt agagatacca tgctcggtca
     3901 gatagttgac cgctgccgct atggttttca gttcatcggc tgtgtgctgt tgttgccaac
     3961 gctgcgaata cttccggctc ttttctctct gaacgctcaa atacttcatc agcagatttg
     4021 caaggccggg ggattgttgc ggctgttccg gggcggtttc ccacgctttg aacaggtcgg
     4081 caatccattc tttgagcttt ccaatctgcg ctcggatttc ccgtataagg cggtttgcct
     4141 tttggatatt ccggttcagt tcgcctttct cggtggcaat acctttcttc tccatctggc
     4201 aagccgccac gcccatgtgg acggtgggta tctcgccaat gccgcgctcg gcgttgctgc
     4261 ggtggtcgat acgctccggg cttccggctc gttcaaggta ggcgtttgaa atatccgccc
     4321 atgccttacg ccacaagagg gcgttgccct tgtcgttcca gccggtcagg tcaactttgt
     4381 gcgtcttgta tctgccgctt ggcaagcgga tacgctcgcc gttttcatca aggtcatatt
     4441 ccttttggga ctttgccgcc catgcgccgc gctcgtcaag ggggcgcatg gtaagcatga
     4501 tgtgacaatg gggattgccc ttgccggtgt cgtgaatggc ataatcaacg cacattcctc
     4561 tggaaacaaa ttgagaggaa cagtattccc ggacaagtcg gatttgttcc tctctggata
     4621 actctatggg gagcgccgcg tcaatctctc tggcaagctg ggcgttcccg gctttctcgt
     4681 aaagctccac gctgttccac aaggttgaac ggtcagagaa agagggcggg gcgtggggtg
     4741 gcagcataat ttccgtatgg acaacaccgc ctttgcgggt gtagtcgtgt gtcattccgt
     4801 cccactcatt tgtcagcttt tcgccgcttc ggtaggcggc tgcggcaacg gctgatttgc
     4861 ccttgccccg gctgacaatg ctgatattac aatgatagat ggctatgggt atcacctccc
     4921 ggataaaatg aaaacccgca aaaatggtac agacgccaaa ggcgggtata ctgtttttgt
     4981 gggtgtgcag ggatagccgc gtaagcggcg caaggggtgc agccccttgt tgcggcaaag
     5041 ccgccaatgt cggtcagaga gggaagcaag cggctttctc tctgtgccga caagccctcg
     5101 gcagagcgca cgcacccgta agggtgtata agtgcgccct ttgtaccaaa gggattattc
     5161 gcttttcccg ccctcggtgc gttttttcag atagccccgc gcttcctcgc tcgtcagggc
     5221 aagccggaga aaggcggcgg cttcttcgtc ggtcatggtc tttgcttctg gcacaatgct
     5281 ctcaaagacc gcaccccgga cgatcagccg atggctgcgc gtcctgcgtt cctcttggga
     5341 taacttttgc cgcaacacct tttcccgatt ttcaagctgc cggattttct tcttcccgtc
     5401 ctcaatctcg gcttgcaatt cctcgcgttt ttttctctcg gtttcgtcat gggtggtcac
     5461 tcctttctac ctgtcggcat agaaaaagga cagtcgattt cctcggctgt ccttttgatt
     5521 agggtgtttg gtttactccg ttctgctcaa taaatgggaa tattaaatat caatacgccc
     5581 tttaatacat tcctattaaa acatcagctt cgattgtcaa atgtgtgaga gtacgccaat
     5641 caacgcaatc tttttcaacg caaaagagaa gcggcgtcat ttcaataaac gacattcttt
     5701 gttctgatga caactgtacg gtggctgaaa ccgtttctct tgaaatggtt ttaagatatt
     5761 tctcaaaata ttcaacgaca gactcatttg aataatctgg atttttcaag tgtgcttgca
     5821 ctttagtcct gatttccctc aaatgatttt tcgtaggaat tactttcaca acatatccgt
     5881 taggagatag caatcgctga aattctttgt agtgtgcagg cgaaaatatg tctaaaatac
     5941 aatccatact tccgtctttc aaagggattt ttgataagtc agtaacaaac cacttcactg
     6001 ctttgcgctt gtcttttttt gatgcaatct gtattgcctc ccttgacaag tcaaaggcaa
     6061 agatgtttcg ttctgttctt tgctgtatct gccttgcata gaaaccctcg ccgcaaccaa
     6121 catctaaaat gtttcttata gatggcgtat cagaaataaa ctgtatgatt ttctccaaca
     6181 caacatcata catgccatac tccaaaattt ggtgccggtt gtcaaaagac cgcttgctgt
     6241 agttggtttt gggcgatgat tttaacaaca aatttacata cccatatctt gaaatatcaa
     6301 agcaatgtcc atgtctacaa attaggctat tgccttgtat atccattgat tttgtgcaaa
     6361 ttgggcattg aaaataaacc ttgctgtctg caaagcgtga taaattatta ttcatttgtt
     6421 tttcctccgt aattacatct ctgtttcaat aagcgagtta tgcaatacgg ataaccgcaa
     6481 cataactcgc ggttttatct taatctcata aatgtaacca ttgtgttgtc ctccaatcaa
     6541 ttccgcagta ttactctgct tttagaaaaa gtatagcaca aaactatgaa catttcaact
     6601 ctatttcagc ctgtcggcga cgttgctctc tctggcatac cgcccgccgt tcctcgctgt
     6661 atggggcggt cagacggaaa gagaagcggc ctttctcaat gtcaaactcc atgcagcccg
     6721 tttccgggtc tgcgtcagtc tgctggcaga tcgccggata acggcggctg tatgcaagca
     6781 gacgcttttt caaggcggtg ttgtgggtgc ggatatggat aagggggtct ttctcgtcaa
     6841 accaaatatc ggtggtcttt tcctgcttgg taagccctgt tctcatgcaa actcctttct
     6901 gtgcccctgt tacgcaatag gggcattttt cgggtgtttt ctccggctct tgacttggag
     6961 aaaacggcgt ttttgacgat aaaaaccgcc cggacgtgga atgtatcgtc ggggcggctg
     7021 ttatcgcaag atttccgatt tttccggctc ttgaccgtca gacgcagata aacacgaact
     7081 gtcggcaagt atcgtcttga gcagcttgtc gcggaatgtt tctgtgctgc tgtgattgaa
     7141 aaataactcc gcaacaatag tctgcccgtt tctctgcgtc gtgataatac tgtcggggtt
     7201 ccggggcgcg gtgggcgtcc cgttctgttc tgtcataggc ggctcctttc tccgggcgca
     7261 aaagagggac ttcccgtagc cggaaaatcc ctcttggttg tcggttattc tgttttactg
     7321 tgcgggctgt gcggcggcgg tctgcgcctt tctccttgcc cggtattccc gcgccttgat
     7381 acggtcatac tcccgctgct tttcaaggtt tcgcgcccgg tactcccttg aatactgccg
     7441 gtgataggcg cggctctttt cctttttggc ttcttcgatt tcctcccgca tttgccggat
     7501 ttcctgctcc gttggctctg taagctgtgt cacttcgttc tcaaatttgc cgatatagtt
     7561 gaaatatatc ccgatgtgct gaatggcttg ttttgccctt ttcttgtcgc gctcatgcac
     7621 ttcaatccgg ctgataaact cgttgagaat ggcgggggtc aggtcggtaa aggcagcgta
     7681 gcgttccgtc agcttcaaaa acttctgcgc ccgtccgccc gcgttctcaa aagcggatag
     7741 ctgctcttgc agctcggcaa gctccgcttt cagcgcatag tattcttctg aatacttctg
     7801 cgacatttgc tcatagcggt cttgcgggat cgtgccgagg gcgttgtcct catagagctt
     7861 gttcagcacc ttgtcaatct gttcaaggcg cgtcgtgatt tgcgggatac gcttctgctg
     7921 tttcttggtc ttgtcggtct gctgcatggc aaggttcttt ttcactaagg cttcaaattc
     7981 cgcccagttg ctgatagaat agtcctcgat tttcttcagc acttccgcga tggtctgcat
     8041 gagcaaatcc gcgtcaatga tgtgcgggga attgcatttg gggtttttgg cttttccctt
     8101 gtggtactcg ctgcaatagg caacatgacg cttgccgcca ttccgataat ctatgcgaat
     8161 gtgcattttc gcaccgcaat ccttacagaa aagcaagccc gacaaagggt ggatttcccc
     8221 gtccccgttg gggcgtttga cgggcgcatt ttccaaaatc cgctgtacgg tttcaaagtc
     8281 ggtgcggtca ataatcggct catgcacatt ttcggttatc tgccattggc tccggtctac
     8341 atagtggttc cgcttgtcgc ggaagtgctt tgtggtcttg aagttgacaa catcaccgca
     8401 atactcctgc cgtgtgagga tatgggtcag ggtggctttg ttccacttat agcggttggc
     8461 ctcattgagc gccctgtttt tacaggttcc ccgcccgcgc tctttcatgt agaatgtggg
     8521 cgttgggatt tgcgcctgcg tgagatatac ggcaatttgg tttcggtttt ttccgtccag
     8581 aaacaggcga aaaatcaaac gaacaactcc ggcggcttcc tcgtcgataa tccaaaaatc
     8641 cttgttgtcc ggggatttga catagccata gggggcttcg gtggcaatcg gctttccact
     8701 catggtggac atttgtccgc cccggccttt ggcaaggctt tctgctcctg caaagccagc
     8761 cttgcccgcc gttttcgctc cccctcggta gaggattggc cgatcagtag ttcaatgttg
     8821 ctcatataca gtgcgccgtt ctgtaacggc tccacaagcc ccagcttcat aaaaatctgc
     8881 aaggcccgtt ctacggtgcc gacttgctga cgggtaatgg tggcaatcat ctgcgcggtg
     8941 taggggatat tttcatcaag ctgcaacttc ccgccgtttt tcagcgattt caggtacagt
     9001 ttcaagagga tgttggaata gaggataccg tcctgcatac tttccagcag cacaatggcg
     9061 tcctcgtcaa agtaattctc tttcagcttg aggtagtagt attttcggtt gtctgacatg
     9121 gttcctcctt tgggtggatt tggggtgttt gtacgcattt agaacgccgt ttccggggga
     9181 aaaggataaa tgtatcgcgt accctttgac acccacgaaa aaagccttga tttatgcggg
     9241 tttgaaaggc tctaaagcgt gacatctctg cctttgtttc cgctttctct cggcggcgcg
     9301 gattttcttc atgcgcccgg cgcagtcggg gcagtatttc ccccggttgg atttggggac
     9361 aaaggccgct ccgcagacgg cacaccgttt ccggctcccc cggtataaga gggctgcgga
     9421 cagctccccg tcaaggggca ggacagccac acggaaccag cggcacatga gggaaaggga
     9481 aatgctctgg acgcacacgc aaggctcccc gtcgtctaac agcaggcagt tcccctcgtc
     9541 gtagttacag cactcatgta ccagccgccg cgcccgccgg tgctggcggt agtccatgcg
     9601 gggcaggtta tcgctcatgg ctctgctcct ttctgcggtg cggctcgtcc cggcgcaaaa
     9661 tctggttgat attccgcttg acggtctgca actccttgaa ccgctgcttc tgttcgtgat
     9721 aggtgttata caggccgtct ttctcggaga taagctgctc gatctcggcc tgcaacgctt
     9781 tccgggcggg cagcttggta atgccatgcg ccttgaaata ccgggcggct gcgtcggcta
     9841 tgataaaatc gctctcatgg gcctgccggt atgcggcgcg ggctttctcg gatttctgcg
     9901 ctttcaaccc gtcgcgggcg ggcttggtct gggcgtaggc caacacctgc cgctgcaact
     9961 cctttttccc ttgcagcttg gtttccagtg ctttcagttc gccgctggtc tggcgcattt
    10021 ccgcataggc ggtatcaacg gcggcttcta actgctccgg ggaagtaaag ccgtactgct
    10081 ggtagacgga cagcgttttg gcggcctgct tcagattgtg tatcttcgcc cagcgttcat
    10141 agccccggcc tttgccctcg gccattttct gctcaatgtc cacaagccgc tgcactccgt
    10201 cctgtttggg ggcggtttga ggggcttttg cgggctgtat gccgcgtttc tcctgccagg
    10261 ggtattcagg tatggctgcg gccttttcta tggctctggc ggcattctgc tccaaaacgg
    10321 caaggacggc ggtgcggtca aaatcgtcgc ccagcttccg ggcggtgatg ggctttgtcc
    10381 tgtccggcgt gagataggac agccgccccc ggctctcctt gacggtcaca ccctcccgca
    10441 gcagcagaga ggaaaactcg tcaaagctgg cggcggtggc aagggctttc cgtatggtct
    10501 gccgcagctt ttccttgttc gtttcaaact tggtctgccg gggcgtgata ccatcggcaa
    10561 tcatgggggc gttctgcttg tccagcgcgg cttgtccctt tttctgcgcc caatactccc
    10621 ggtcggtgat gcggttcttg ctgccgttca agaggtcgat ttggtaaagc ccctcccggt
    10681 ggcacatctc catgacttcg gatttgaagt agcgcagggc agcgtcggta catcggtgct
    10741 tgcagccggc tttcgtgtcg gctggcctgt ccatgtaggg caggaacggc acttcctcaa
    10801 tccgcaggct gtttatgacg atatgcacat gaatgttgcc gctgtggtta tgcccgtccg
    10861 ggtgggtgca gacaagggct tggtggccgg ggaaatgttc tttacagaat tgctccccca
    10921 acgcctgcgc ccggtctacg gtcaggccgt tgtccggccc gtcccgcggg tcaaagctga
    10981 tgatgtagtg gtggcttttc acatcttccc gccgctggtt tttctcatag cggagattgg
    11041 cccgcataca cgcaacggca aaatcctccc cgccgcagtt cagcgtagac agccggtagt
    11101 cctcgcgggg gataagcctg ccggtttcat caaggacggg cttcatggta aattcgtcat
    11161 gctcaaagag caggtattgt tcggcggctc cgtagtcggc gtttttagag ttgatatgtt
    11221 tgagtgttgc caaccgcgtc acctactttc tttaagactt catacttgag ggcggcaagg
    11281 tcggctatgg cggcgcgtac ctcgccggac aacgcatgat agggcgcgcc gtactcgttc
    11341 agataccggg caatctggtt gaggttgccg ccgatcctgc cgtactcggc tgcgagcttc
    11401 ccgacagcgg agagcagttc gtcattgacc gacgacacat ggagtacggg gcgtatggtg
    11461 gtacgccgga tcgcctgccg gagaaattcc gactggctga taccataggg cgcaagccgc
    11521 gctgtgaagt cggcgtattc atcttcggtc agccgggttt tcacaacgcg gctgcggtgg
    11581 ggtgtgttgt atttttttcg catggtcgtg acctcctttc ttgccgcatg agcgcggcgg
    11641 ggataagcgg cgcaagccgc atagcagggt ttggggaagg cactccccaa caagtttccc
    11701 gcgaggggca aaaccgcaga attgcggatt ttggcaccgt ggtagaaact tgctctcgct
    11761 ctcgctctcg cttctcttta cattgacaac acaaagccca tttgctataa tatcgcgaag
    11821 aagaacagcc atgttgttct aatttcagta tcggaggtat aactgcaaaa acagaaacaa
    11881 gtcttttaac ggcgctttgg gcactttagg aggccttttc taaaatcact gttagaaagg
    11941 gctgagaagt ttgcccttcc tgcgcggcag tcgggcttgt ttcacaaaac aacccactga
    12001 ttcgtaaagg agaatgtaac ttcatgtttg ctaaaaattc aaaggcatat tctgtctacc
    12061 tgctgttccg atttgtcttt tccctggcgg tttctatgtc cacagtgctt tccatcgtgt
    12121 accacctgga ggtggtgcag ctggatgctt tccagcttgt cctggtaggg acggttctgg
    12181 agacctcctg ctttctgttc gagataccca ccggtgtggt ggcggatttg tatagccgtc
    12241 ggcgctcggt gctgattgga atgttcctct acggcctggg ctttctgatg gagggtgcgc
    12301 taccgtggtt cgcgccggtt ctgctggccc aggttgtctg gggttgcggt gataccttca
    12361 tcaccggcgc tctggaggcg tggattgcct cggaggaaga ggacaaaccc atagacaagg
    12421 tgttcctgcg gggcagtcaa atggggcaaa tcggcggcgt tctgggcgtg gtgctgggca
    12481 cactgctggg aaacataaac ctgcaaatgc ctgtcatctt ggggggcagt ttgtgcttgt
    12541 tgttggggct ggtgttggtt cgcatcatgc cagaaaccaa cttctcccct gctattgagg
    12601 aacggcaggg cttgcttaaa gactttgtct gcctgttcaa gctcaacctg ggctttgtga
    12661 aaggcgcacc tgtgttgctg gcgctcttag caatcacact atgcggggga cttgccagtg
    12721 aaggctttga ccggctctcc accgctcatt ttctggatga cacggtaata cccgttatcg
    12781 ggccgctgaa cagcgtcact tggttcggtg ttatcagtct tatcggcagc ggcttaggta
    12841 ttctggcttc tcagttgctc atcgcccgca tggagaaaaa agggactgtc agccgaacca
    12901 gtgtggtcat gtccaccagc gccgggtata tcctgtgcct ggttctcttc gcggtggggc
    12961 ggagcttttg gttcatgttg ttggtgttcc tgctggcggg gcttatgcgc accatcaagg
    13021 agcctgtgct ggccgcctgg atgaacgacc atgtggatga gaaaatgcgc gccacagtct
    13081 tttccaccag cggacagctg gactctttcg ggcagatcat cggcgggcct attgtggggc
    13141 tggtagccca gcaggtgtcc ataccctggg ggctggtctg taccgctttc ctgctgttgc
    13201 ccgcgctgtt cttagtgccg gtggcgggaa agaagcggga ttgatatggc atagttaagt
    13261 ttactgacga gcgggagatt acttccgctc gtcttcattt agtagcgcaa aatttgagga
    13321 ctctttattt ccttattcgg tatagcggag gcggctgtca attcgacata attttcttgt
    13381 gatactttac cgtacatgag cattcgcacc cggattgtcg ttaccatatc cctccagaag
    13441 attgataacg ccccaaatgc ctaagcctgc tccaagagcg ataacaaggg tctgcaatac
    13501 gtttactgcg ctgttgaaaa atgccatata atatcctcac tttctgccgc tttgcggcga
    13561 taaaaattgt ttgtttttgg ttttgggtat gaaaaaagcc gcctgtgttc ggcggctgcg
    13621 tcctcgcgct gcttaaactg ctgcggcgcg gcggtattca gttgtcattt ttgtaagggt
    13681 tgatacgctg cggcttcctg ccacgctcca agtaggggcg cgtaccatat agcccgtgtt
    13741 tacagttcgg atagattacc acctcccttt acggtgctgc gtcctcctgt acgtcgattt
    13801 cgtagtagtc aaatacttcg tccggcttta cgatagcggg gcggcgtttg atatgctttt
    13861 ccatgtcaaa ggcgtttttc gggtctgcgt cggacaggta cttgtatttc gggtgcttcg
    13921 tgatgtcgta cttatcagag aagaacgggc gcacacctct aagctgcaag atacatttcc
    13981 cgccgtccat gaccgcgatt tcgtcctgcg tcataagctc tttgcctaac ttctgatagt
    14041 tcagcccatg cgaaagctcc cgccctctgg tttcggaagt gttgaagctg tcaatcgttt
    14101 ctttgcctaa gatttccgat atttctttga gcgtcgtttt ttccttgccg cccaagaaaa
    14161 gggtcgtgtc gcagttgccg actatggtat cggcgttgtc cttgtagatt gcctttagct
    14221 gcgactgtga ttgcaaaata atagaagccg atatttcgcg gcttcgtatg gtcgctatga
    14281 gcttttcaaa cttcgggatt tgaccgatat tcgcaaattc atctaacagg cagcgcacat
    14341 gaacaggcag ccgcccgccg taaacatcgt cggctttgtc gcataacaag ttgaaaagct
    14401 gcgtgtagag aatggaaaca acaaaattga aagtgtcgtc ggtgtcggag atgataacga
    14461 acaatgccgt ttttctatct cccaaagtgt caagctccat ttcgtcggtt tccatgagtt
    14521 cgcgcagttc ccgtatgtca aagggggcta accttgcgcc gcaggaaata aggattgact
    14581 ttgccgtttt gcctgatgca aattgtcaag gactttttaa tcatgtttac aaaaaagtca
    14641 cattttcgcc acctcctcac gaagcagacg cttgattttg tcctccatcg tctcttttgc
    14701 gttttcgctg aaatggacac gaaccacata ggtggtcttg tcgatggtct tgcggtagca
    14761 aggctgtgtg tgctgtgcgg tggtctggat tgtgtttgtg ttcattgaat acctcctcga
    14821 aatgagaaaa gcccgacaag gaaaggtctg acaacgaagt accgacaacg gacttctgaa
    14881 aacctttttt cttaatcggg cttatctatc tttttactat ttactttttc ttttatattt
    14941 ctgttgtcat tgttgtcaga gaaagaaaag ccccacaaaa tcaaggaatt ttcgctttct
    15001 gcccgacaac cagaccgaca accggcttga caatctgccc gacaacgaac agcaattttt
    15061 attccaacca ttctttcgga agttcaagct gttgcatttc tgcttccgtc agttcgtgaa
    15121 attttcctgt gttgttgtca ggctcgttgt cgatggggat gcgttcccaa cctctctgtc
    15181 tgcggtatgg ctctggaaaa tagcgagggt tagcaaatgc cttccaacct gtgacggcat
    15241 tattcataat atcgttgatt tctcgcagtt cccattgctt cggctcgtca tagtcgtgtc
    15301 ccaacgcttc acgataaagc tgcttggagc agactgtatt gccggaatag cgttccagat
    15361 aatcaataat ctgtccggct ttggtgtcct ccggcatgaa ctctttctga tgggctttca
    15421 gaaattcatc tgttgaacgg ctgagtttca gcttgaaatt gccgcttcgg taaatctcca
    15481 tcgcttctgc ccacatctga atgatatatt ctctggatgt agcttcatct tccagaatgt
    15541 gaacctctgc ctgttccggg cagaccatga caggaagaaa gcggcggttg cctgtacggt
    15601 caagcggaag aaaatcaagt gtattggaag aacctccaaa cacgcattgt ctctttctgt
    15661 ctgccggatg ggtctcatac ggtatcttgt atgtttcctt ttgtcggctc agaaaggact
    15721 tgatttcttc aatgctcttg gcgtttgctg tggcaatcat ttcagacatt tcgattatcc
    15781 aatgcccttg catcttgcga tagacattat catcgtccag tttcttcaaa tcatcagaga
    15841 accagtcatc attgacggca agcagacgga agaatgtgga ctttcctgca ccttgaccac
    15901 ctaccagaca gagcatgact tcaaatttgc atcccggctt gaatactcgt gagattgcac
    15961 cgagcataaa cagcttcaat gcttcataag tgtactcgtt ttcttctgaa ccgaggaaat
    16021 gatgcagaca atggcggatg cgttcctgtc cgtcccattt cagagaatta agaaaatcgc
    16081 agactggatg ataacggttt tcgttggcga tcaccgttat cgcatccacg attttctttt
    16141 caacagtcag tccgtagttt tcttcaaaat acagaaccag atactttata tccacatcgg
    16201 ttagggtggt actgtcacga taccagccga ggggctttac aatatcaatt cgctccgtca
    16261 gcagattttt tcggatagca ccttttagca gagggtcgca ttgcagaacc ctcttgtaat
    16321 tggcggctgt gttatagacc ttacctttct ggctctgctc caaactgttt cggacttcgt
    16381 ccacggtatt ctgcaattcg ttgttcaagt ttcatcacct cttttctttg ctccgctaca
    16441 agagcctgtt tttcttcttt cgtgccgtca atcaaagtat caatgagata ttcgatatgg
    16501 ctttttcttt gcagggcttc cacgaacagc ggatgccaca catcatccgg ctgtttcggt
    16561 gcgtgttggg tctcccatct tcgcagaaga tgaaaataat ctgtcagcac tctgtaacat
    16621 cgtgcttctt ctttttgata aagttgctcg gcagtaggtt ctcggatatg gggtctgact
    16681 gtcggcttgt gtctgctgtc atagctgata ccaaaatcgt cagccagttt catagctgct
    16741 tctttgcagg gcagaccgca cagacgggaa acgaagtcaa ttacatctcc gtcagcttgg
    16801 caagcaaagc aatgaaaacg cttatcgact ttcatgcttg ggttcttatc attgtgaaat
    16861 gggcagactg ccatgccgtt gcggttgacc ttgatgccgt acatctcagc cgcctgtcgg
    16921 gtgcttatat tgggttttac tgcttcaaat acattcaaat catcacttcc tctctgaaac
    16981 gaaaaaaggc actcgacttt tcacaatgaa aaaggcaagt gccgtgttag agttccatat
    17041 tctgtttttt ctgtttgtgc tgcggagatt tcggctccag ctgttttttc tgctcttgca
    17101 gatacttcat cttttccgtg acggagtgct tcggctccgg cttcttttca acctcgccct
    17161 gttccggctc gatgactttg cttatccagt agcggacatc tttcagtggc tgaagctcgg
    17221 ctttgacctc ggacagcttc gcattgtttt ctgcaacgga cttttccaga gtgtcaaatt
    17281 ctgattgcaa cgcagtcaga tctacacgaa ggtcaagtcc ttgctttttg aggtaacgga
    17341 acgatttgtc aaaagcagaa agagcgtcct tgtgagtctc agcgtaaact gcctgtgccg
    17401 ctttccatcc gattttcaga tacttgtctt tgactgcttt gtgctctttg cagacggaga
    17461 ccgctttctg aatctgcgtg atggttttca ttcgggtctc ggctgtctta atcgcacttc
    17521 ggattgatgc ggctctgcca ttcacttctt gcagagcttc atctaaatct ttcagcgtgt
    17581 agagattgtg gtctctcaaa tatgcgacag ctttggaaac tgcctgcaca tcagcaagac
    17641 tgcctttgtt ctgtccgtag cgagaccagt cccggcgttc ctcttttctg acattaagat
    17701 actcattgag caatccggca agtgtcgggg atgcgttctg ttctttcatt tcagcaagag
    17761 cttctttcgt ggcttcgctt acatcagcaa tccattcaag cagagacttg atggttttgc
    17821 ggatggctgc catcagactg ttggcagatt tgatgtcacg gttgagatta ccgatattgg
    17881 tttcaatgcc tttgcgttcc atagcagaga cagcggctcc catgtggact gtcgggataa
    17941 catcaatccc ttgtctggca taagaacgca tatccactcg ttcgggactt ccggcaagct
    18001 ccagatattt attctggata acttcccatc cgtgtctcca ttcctcggcg tgatactgtt
    18061 cgttccaatc aacagtatct tccttatggc ttttccatct gccggaggga agtttgatac
    18121 gctcgccgtt ctcgtcaagg tcataaacct ttcggctctt tggcatccac tttccatttt
    18181 catcaatggc tcgcatagtc agcatgatgt gacaatgggg attgtgtccc ggtgggtcgg
    18241 ggtcatggat tgcaatatca caacacattc ctttggagac aaagtactcc tcgcagtatt
    18301 cctgtaacat ctgcggacac atttcaaggg gaacttctct cggcagggca acaacgaaac
    18361 gccttgcaag ctgtgagttc cattgcttct ccacctcctc ggctgagttc cagagcgttt
    18421 ctctgtcggc atattcgggt ggagcatttg ccggaagcat gatttccgtg taaacaactt
    18481 ccttttgttt tctgcggtgg tctttgtttt tctgatcgta ctcggaaaac aatttttctc
    18541 cggcttgata ggcagctccg gcaacagcag aactgccttt gcttctctga acaattcgta
    18601 tgttcagatg tggtatgggc attttcatca actcctttct cgataatgga taaaataaaa
    18661 gcgaccaact ttttacggtt gatcgccttt ggcttagtca ttattaaatt gtcattatga
    18721 tgcgtggaac tggaaattta cgaattttgg gtatatttta gaagcagtat gccttttatt
    18781 agcaacaaca taaatgcgac tgtaattgca tacgcttctc ttgccatgcc taaatacaat
    18841 acagttaaaa tactcaatcc cagtgaaagg ctcgttataa tgctttgtcc cctttctgtt
    18901 ttgagctgtg tcaaagcaat ttttgtgatt cccataacaa tcagagcaag gtaagagacc
    18961 caatacagta ttatattaaa gaatgctgtg tcagtatatg aaaataggtt caccgaataa
    19021 atatatccgt taattgggtt cggataaaga ggcaatacaa tcagcataaa agaaaacaaa
    19081 tccacaattc caaaaagcaa actgcacatt ctttgaaggt tcgctttatt ctctttttct
    19141 gcaatggaaa gcagcttttc tccagacaat aactcatcaa tagtcaccga aaagaactta
    19201 gatatttcct ttagtgagtc aatgttcgga tatcctctgc cggtatcaca tagttaaaga
    19261 tattggtatc attcaatcaa ttttgccgat aaagcggtag aagatttcta cctcctgttc
    19321 ccggcttccg tcctcacctt tgaccgcttc atggacaacg attttttcaa tcagcatatt
    19381 caaaagttcg gcggtcagtt ctgttggatt gacgcactct ttcatcaagg caatccattt
    19441 ttctgcgtct acggcgttct ggctttcagt ggcgatagcg gattgaagct gttcaatctt
    19501 ttcgtccagt tcagcctgtt cgctttggta cttcccggac agcatagaga agttgtattc
    19561 cgtgatacgc cccgccgccc agtcctcata cgtccgggca aacaaagtat cgacttcggc
    19621 ttttcgcttc tctgcctttt tcagttctgc ggcctgcttc tttcttgcgg cagcctgtcc
    19681 cttatcagtg gcatttaaca gctgcttcaa gagccgttct tcatcatgct gtaccagccc
    19741 cgaccagtat tgcagacggg agaggacata ggcataaagc acatcataac ggatatagtg
    19801 catggagcat tggcgtgtgc cctgcccgta cttgctacaa tgataatggc cgtaaggctt
    19861 gctgttctgc ctgttctccc cataggacag cgaccagccg caatccgcac attttaccaa
    19921 tccggaaaaa atctgcgttg taccatcctt gcacttcctg cggcggtttg ctatctgctc
    19981 ctgtacctgc cggaaaacct gctcgctgat aatcggctcc tgcgtgttct ccacccgcac
    20041 ccattcactt tggggcttgc gtaccctccg cttgttctta aaggaaatgt tcgtttcccg
    20101 gtaatgaatg gtatggccga tataggtttc gtctttcata atgctcttga cctgggctat
    20161 cgtccatgcg tagctttttt cctccggcgc acccgcatag atgtttgcaa aagtcccgtc
    20221 acgctggaag ttgataaatc ccggtgtggg aaccttttcc gcaatcagta ttcttgtgat
    20281 actggccgcc cctctgccat gaatagcaag gtcaaaaatc ttctccacta tccagcgggt
    20341 ttcctcgtcg attatcagct tgtttttgat ttccgggtgt ttcctgtacc cgatgggagc
    20401 ataggcgccg atacgctgtc ctgtggcaaa ctttgctttg aaagcggcct ttaccttgcg
    20461 gcttgtatct ttcgcaaacc attcattgaa caggtttttg aacgggacaa aatcggaaag
    20521 ccctttctct gtgtcctcat tctccgcaac ggcgatgtag cgaacccgtt tctccgggaa
    20581 cagaaattcc agatagtagt ccatcatcac atgttcccgc ccgaaacggg acaggtcttt
    20641 cgtgacaatg cagtttactt ttccggcttc catatcgtcc atcatgcgct gaaaatccgg
    20701 ccgttcaaag ttcgtccccg accagccatc gtccacatac tcaccgacta catgaagccc
    20761 ctgttccttt gcgtactgtt gcaggattgt ccgctgtgtt tcaatgctta cgctgtcacc
    20821 atagttttca tcgtcccggc tcaatctcat ataaagcgcc gtgttg
//
LOCUS       DAMKOJ010000248        18034 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.073, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000248 DAMKOJ010000000
VERSION     DAMKOJ010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18034
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.073"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            337..651
                     /locus_tag="PC592_003821"
     CDS             337..651
                     /locus_tag="PC592_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF4057699.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            667..1053
                     /locus_tag="PC592_003822"
     CDS             667..1053
                     /locus_tag="PC592_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF4057700.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1082..2467
                     /locus_tag="PC592_003823"
     CDS             1082..2467
                     /locus_tag="PC592_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF4057701.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2470..2622
                     /locus_tag="PC592_003824"
     CDS             2470..2622
                     /locus_tag="PC592_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4057702.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2645..3850
                     /locus_tag="PC592_003825"
     CDS             2645..3850
                     /locus_tag="PC592_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF4057703.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            3893..4114
                     /locus_tag="PC592_003826"
     CDS             3893..4114
                     /locus_tag="PC592_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057704.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4231..4728
                     /locus_tag="PC592_003827"
     CDS             4231..4728
                     /locus_tag="PC592_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF4057705.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            4703..5209
                     /locus_tag="PC592_003828"
     CDS             4703..5209
                     /locus_tag="PC592_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4057706.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5193..7640
                     /locus_tag="PC592_003829"
     CDS             5193..7640
                     /locus_tag="PC592_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF4057707.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7643..9820
                     /locus_tag="PC592_003830"
     CDS             7643..9820
                     /locus_tag="PC592_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF4057708.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            9817..10818
                     /locus_tag="PC592_003831"
     CDS             9817..10818
                     /locus_tag="PC592_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF4057709.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            10815..11747
                     /locus_tag="PC592_003832"
     CDS             10815..11747
                     /locus_tag="PC592_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF4057710.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            11992..12108
                     /locus_tag="PC592_003833"
     CDS             11992..12108
                     /locus_tag="PC592_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDF4057711.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12124..14043
                     /gene="tet(M)"
                     /locus_tag="PC592_003834"
     CDS             12124..14043
                     /gene="tet(M)"
                     /locus_tag="PC592_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDF4057712.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14162..14329
                     /locus_tag="PC592_003835"
     CDS             14162..14329
                     /locus_tag="PC592_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDF4057713.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14389..14742)
                     /locus_tag="PC592_003836"
     CDS             complement(14389..14742)
                     /locus_tag="PC592_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4057714.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15247..15669
                     /locus_tag="PC592_003837"
     CDS             15247..15669
                     /locus_tag="PC592_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF4057715.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15666..15896
                     /locus_tag="PC592_003838"
     CDS             15666..15896
                     /locus_tag="PC592_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF4057716.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16357..16560
                     /locus_tag="PC592_003839"
     CDS             16357..16560
                     /locus_tag="PC592_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF4057717.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16642..17859
                     /locus_tag="PC592_003840"
     CDS             16642..17859
                     /locus_tag="PC592_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF4057718.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         5922 a         3233 c         3746 g         5133 t
ORIGIN      
        1 aaaaatagca taaaaatcta gttatccgca taaaaactgg acttatcaca ctttatcaag
       61 gtcaaaacca ctcaatttac tactaattta ctacttatga atgagctttg atacgacgat
      121 ttatccttga aaagtgaaga tataaagata cttccaataa aatttgaata tttaataggt
      181 agacacttca aaaaatgagg tgtctatttt tttacccgat tttgaaagga agtgaactta
      241 tgaaaacaaa aaatcaagaa tcaaaaggtc gttccccact ctttaagacc atcaaacatt
      301 cattcagcca ataaaaaaga aaggataggt aaaaatatgg aacttaaatt tgtgattccc
      361 aacatggaaa aaacattcgg caatttagaa tttgctggcg aggataaagt cgttcagcga
      421 agaatcaacg gacggctaac tgtcttatca agaagctata atctctattc tgatgttcaa
      481 agagcagatg atattgtggt ggtgcttcct gctgaagctg gcgaaaaaca tttcggcttt
      541 gaggaacgtg tgaagttagt caatccacgt attaccgcag agggctacaa aatcggcact
      601 cgtggtttta caaattacct tttacatgct gacgacatga taaaagaata aagaaagaga
      661 ggaaaaatga tgagattagc aaatggcatt gtattagata aagacacgac ttttggagaa
      721 ttgaaattct ctgctctacg tcgtgaagtg agaatccaaa atgaagacgg gtcggtttca
      781 gatgaaatca aggaacgtac ctatgactta aaatccaaag gacaaggacg catgattcaa
      841 gtaagtattc ctgccagcgt gcctttgaaa gagtttgatt ataacgcacg ggtggaactt
      901 atcaatccca ttgcggacac cgttgctact gccacctatc aaggagcaga tgttgactgg
      961 tatatcaagg cagacgatat tgtgctgaca aaggattcta gttcattcaa agctcaacca
     1021 caagcaaaga aagaaccgac acaagacaaa tagtcgctag gtagaaagga gactttttcg
     1081 catgaaacag cgtggtaaaa ggattcgccc atctggtaaa gatttagtct ttcattttac
     1141 gatagcgtca ctcctgcctg ttttcctgct ggttgtcgga ctgtttcatg tgaagacaat
     1201 ccagcagatc aactggcagg attttaacct atcacaagca gataagattg acattcccta
     1261 tttaattatc agtttcagtg tcgcaattct tatctgcttg ctggtagcgt ttgtattcaa
     1321 acgggttcgc tatgatacgg ttaaacaact ttaccaccgt caaaaactgg caaagatgat
     1381 acttgaaaac aagtggtatg aatctgaaca ggtcaaaaca gagggtttct ttaaagatag
     1441 tgctggtcgt acaaaggaaa agataaccta cttccctaaa atgtattatc gacttaaaaa
     1501 tggcttgata cagatacggg tggaaatcac gctgggaaaa tatcaagacc aactcttaca
     1561 cttggaaaag aaattagaga gtggcttgta ctgtgagctg acggataaag agttaaagga
     1621 ttcctatgtg gaatatactt tgctctatga caccatagcc agtcgtattt ctattgatga
     1681 agtagaagct aaagatggta aacttcgctt aatgaaaaac gtatggtggg aatatgataa
     1741 gctccctcat atgttgattg ctggtggtac aggtggcggt aaaacttact ttatactgac
     1801 actgattgaa gccttgcttc atacagattc aaaactgtat attcttgacc cgaaaaatgc
     1861 tgatcttgcg gacttaggtt ctgtgatggc aaatgtctac tatagaaaag aagacttgct
     1921 ttcttgcatt gaaacattct atgaagaaat gatgaaacgt agtgaggaaa tgaagcagat
     1981 gaagaactat aagactggca aaaattatgc ttacttaggt ctcccggcac acttcttaat
     2041 ctttgatgaa tacgtcgctt tcatggaaat gctgggaaca aaagaaaaca ccgcagttat
     2101 gaataagctg aaacagattg tcatgttagg tcgtcaagct ggcttctttc taatactggc
     2161 ttgtcaacgt ccagacgcaa aatatttagg cgacggaatc cgtgatcagt ttaatttcag
     2221 agtggcttta ggtcgtatgt ctgaaatggg ctatggcatg atgtttggca gtgacgtaca
     2281 aaaggatttc ttcttaaagc gaatcaaagg tcgtggctat gttgatgtag gaacaagtgt
     2341 catatcagag ttttatactc cccttgtacc aaaaggatat gatttcttgg aggaaattaa
     2401 aaagttatcc aacagcagac agtccacgca ggcgacgtgc gaagcggaag tcgcaggtgt
     2461 ggactgatct tgctggctgg tgtggcaata gccacgccag cacttaaccc cccgtatcta
     2521 acaggggggt acaaatcgac aggaaacagt caaaaaaaca ttagaaaatc ctttggttac
     2581 aagggattta caaaatttca gcgtatgtca aatgggcttt aaaagttgac atacgccttt
     2641 ttgattggag ggatttttac tgaatgaaca aacttggtta cagcatttaa aagaaaaacg
     2701 cttggcttat ggactatctc aaaaccgttt agctgttgcg actggtatta caaggcagta
     2761 tctaagcgat attgaaacag gaaaagtcaa gccatcagag gatttacagc agtccctttg
     2821 ggaagctctg gaacgcttca atcccgacgc tccccttgaa atgctgtttg attatgtaag
     2881 aattcgcttt ccgacaacag acgtacagca ggtggtcgaa aacatcttac aactgaaact
     2941 gtcctatttt cttcatgagg actatggttt ctattcttat tcagagcatt atgctttagg
     3001 cgacatattc gtcctttgct cccatgaact ggacaaagga gttctggtgg aattgaaagg
     3061 tcgtgggtgc agacaatttg aaagctatct tctggcacaa caaagaagct ggtatgagtt
     3121 ctttatggac gttttggtgg ctggcggtgt gatgaaacgc cttgaccttg ccattaacga
     3181 taagacaggg attttaaata tccctgtact cactgaaaag tgccaacagg aagaatgtat
     3241 ctccgtcttc cgcagtttta aaagctatcg cagtggcgaa ctggtacgca aagaggaaaa
     3301 ggaatgtatg ggaaacaccc tctatatcgg ttcattacaa agtgaagttt atttctgtat
     3361 ctatgaaaag gactacgagc agtacaagaa aaatgatatt cccattgaag acgcagaagt
     3421 aaaaaaccgt tttgagattc gattgaaaaa tgagcgtgcc tattatgcag tccgtgattt
     3481 actcgtctat gacaatccag agcataccgc ctttaaaatt atcaatcggt atatccgttt
     3541 tgtagataaa gacgattcca aacctcgttc tgattggaaa ctgaatgaag aatgggcttg
     3601 gtttattggg aacaatcgtg aacgattaaa actaaccaca aaaccagagc cttactcctt
     3661 ccaaaggacg ctgaactggc tatctcatca agttgccccg accttaaagg ttgcgattaa
     3721 acttgatgaa atcaaccaga cgcaggttgt aaaagacatt ctcgaccatg cgaaactgac
     3781 agaccgacac aagcagattt tgaagcaaca gtcagtaaaa gaacaggacg tgataacaac
     3841 aaaaaaataa ctcaaataca aattcattga atatagagag gagaacattt ttatgaattt
     3901 tggacaaaac ctttataact ggtttctatc aaacgctcaa tcactggtgc ttttagcaat
     3961 cgttgtgatt ggcttgtatc ttggcttcaa gcgtgagttt agcaaactga ttggcttttt
     4021 aattattgcg attattgcgg ttggcttagt cttcaacgct gctggagtaa aagacatttt
     4081 actagagcta ttcaatcgca ttattggtgc ttaaataaaa ccgttctttt gtggaatata
     4141 agtggttttc ttatgttccg caaaggaatg gtacaccaaa cgaagtgcgg tagggatttt
     4201 tgaatctcta caaagaaagg acgtgaatat atggacgata tgcaagtcta tattgcgaat
     4261 ttaggcaaat acaatgaggg cgaattggtc ggtgcgtggt ttacctttcc cattgacttt
     4321 gaggaagtca aagagaaaat cggcttgaat gatgaatatg aggaatacgc cattcatgac
     4381 tacgagttac cctttacggt tgacgaatac acttccattg gcgaactcaa tcgactatgg
     4441 gaaatggtat cggaattacc cgaagaatta caatcggagc tatctgctct gctcactcat
     4501 ttttcaagca ttgaagaact aagcgaacat caagaggata ttatcattca ttccgattgt
     4561 gatgatatgt atgacgtggc acgctactac attgaagaaa cgggtgcttt aggcgaagta
     4621 ccagctagtc ttcaaaacta tattgattat caagcctatg gtcgggattt agacctttca
     4681 ggaacgttta tctcaaccaa tcatgggatt tttgaaatcg tctattaaat ctgtcggtac
     4741 attactactg gcagattttc tattttacgg ggtggctcaa tcagctaccc ctatttttta
     4801 tgaaaggatt gattacatga agaaaatacg aagctatacc agtatctggt ctgtggaaaa
     4861 ggtactgtat tctatcaatg attttagact tccgtttccc ataaccttta cgcaaatgac
     4921 atggtttgtc gtgtcactct ttgcagtgat gatacttggc aacttgcccc ctctttccat
     4981 gatagaggga gcatttctca aatactttgg gattcctgtg gctttcacat ggtttatgtc
     5041 tacaaaaact tttgatggta aaaagcctta tggatttttg aagtctgtca ttgcttatgc
     5101 actgcgacca aagctgacct atgcaggaaa aaaagtaacg cttggcagaa accagccaca
     5161 agaagccatt acagcagtta ggagtgaatt ttatggcata tccaattaaa tacattgaaa
     5221 acaatctcgt ctggaataaa gacggggaat gttatgctta ctatgagctt gttccttaca
     5281 attactcatt tctaagtcca gaacagaaaa tacaagtgca tgattctttc agacagctta
     5341 tcgcacaaaa tcgtgatggc aaaattcatg ctttacaaat cagtacagaa tccagcatac
     5401 gttctgcaca agagcgttcc aaaaatgaag tcactggcaa gctcaaagcg gttgcctatg
     5461 acaaaatcga ccaacagaca gacgctttaa tatccatgat tggcgaaaat caagtgaact
     5521 accgtttctt tatcggcttt aagttgcttc tcaacgatca ggagttttct atgaaaagtc
     5581 ttaccgttga agcaaaaaat gctttgtctg attttgtcta tgatgtgaac cataagctga
     5641 tgggcgattt tgttagtatg agtaatgatg aaatcctgcg ttttcagaag atggaaaagc
     5701 tcttagaaaa taaaatctct cgtcgtttca aaatccgcag gttagataag gacgacttcg
     5761 gctatctgat tgaacacctt tacggacaga caggcactgc ctatgaagag tatgagtacc
     5821 atctatcaaa gaaaaagctg gataatgaaa cgctgattaa atactatgac ttgattaagc
     5881 ctactcgctg tttggtggaa gaaaaacagc gatatttgaa aatccagcag gaagatgaaa
     5941 ccgtctatgt agcttacttt accattaaca gcattgtcgg agaactggac ttcccgtcct
     6001 ctgaaatctt ctactaccag caacagcaat ttacattccc gattgatacg tcaatgaatg
     6061 tggaaattgt agcgaatcgt aaagccctat ctactgtccg caataaaaag aaagaactga
     6121 aagacttgga taaccacgct tggcaaagtg ataatgaaac cagctccaat gtggcggaag
     6181 ctctggaaag tgtgaatgag ctggaaacca atttagacca aagcaaggaa tctatgtaca
     6241 agctgtctta tgtggtaagg gtatcagcaa atgatcttga cgaactcaaa cgtcgttgta
     6301 atgaagtgaa agatttttat gacgatttaa gcgtaaaact ggtacgacca tttggggata
     6361 tgctcggctt acatgaagaa tttttacctg ccagcaagcg ttatatgaat gattatattc
     6421 aatacgtgac ctctgatttc ctcgctggtt taggttttgg tgctactcaa atgctggggg
     6481 aaaatgaggg gatttatgtt ggctacagct tagatactgg acgcaatgtc tatctgaaac
     6541 ctgctcttgc cagtcaaggg gttaagggtt cagtaaccaa tgcgttagcg tcggcttttg
     6601 ttggttcgct gggtggtggt aaatcctttg cgaataacct tatcgtctat tatgcggtgc
     6661 tttatggggc acaagcagtg attgtagacc caaaagcaga acgtggcaga tggaaagaaa
     6721 ccttgccaga gatttcccat gaaatcaata tcgtcactct gacttctgat gagaaaaaca
     6781 aaggcttact tgacccttat gtgattatga aaaatcccaa agattctgaa tcactggcta
     6841 ttgatattct gacattcctt acggggattt cctctcgtga tggggaacgc ttcccaatcc
     6901 ttagaaaagc cattcgtgca gtaaccaata gtgaagtacg agggttgatg aaagtgattg
     6961 aggaattacg ggttgagaat acgccactaa gtaccagtat agccgaccat atcgaaagtt
     7021 ttacagacta tgactttgca catttattat tcagtaatgg ttatgtggag cagtctatca
     7081 gcttagaaaa acaactgaac attatacagg ttgcggactt ggtacttccc gacaaggaaa
     7141 cttcctttga ggaatatacc actatggagc ttttatccgt tgctatgctg attgtcatta
     7201 gtacctttgc tttagacttt atccatacag accgaagcat tttcaagatt gtagatttag
     7261 acgaagcatg gagcttttta caggtagcac aaggaaaaac actatctatg aagctggttc
     7321 gggctggtcg tgctatgaac gctggggtat atttcgtgac ccaaaataca gacgacctct
     7381 tagatgaaaa actgaaaaat aacctcggct taaaatttgc atttcgttcc actgacctta
     7441 acgagattaa aaagacctta gccttttttg gtgtagaccc agaggacgaa aacaatcaga
     7501 agcgattgcg tgatttggaa aacgggcaat gccttatcag tgatttatat ggtcgtgtcg
     7561 gtgtgataca gttccaccct gtatttgaag aactgctcca tgcctttgat accagaccac
     7621 ctgtgcgaaa agaggtgtaa atgtgaaacc atcaatagta aacagaataa aatcaaactg
     7681 gacgctgaaa cgtctaggta aagtggcaat gacagtggct ttcacacttg tgattgccat
     7741 ttttctttta gccatgctgg gaacggtggt tcaagctgcg ggcttggtag atgatacggt
     7801 caatgtggca aatgaataca gccgataccc acttgaaaac tatcaactgg atttttatgt
     7861 ggataatagc tggggctggc ttccgtggaa ctggtcggac gggattggaa aacaggtcat
     7921 gtatggacta tatgccatta ccaattttat ttggacaatc agtttgtatg tttccaatgc
     7981 gacaggttac ttagtacagg aagcctattc cttagacttc atttccgcta cagcagattc
     8041 cattggtaag aatatgcaga ccttagctgg tgtgagtgca aacggatttt caacagaggg
     8101 tttctatgtt ggattcctct tactcttgat tttggttctt ggggtttatg ttgcctatac
     8161 gggactgata aagagagaaa ccacaaaggc aattcatgcc attatgaatt ttgtgctggt
     8221 gtttatccta tcggcttcct ttattgccta cgctcccgac tacattaaaa aaatcaatga
     8281 cttttcatca gacatcagta atgccagttt atcacttggc acgaagattg tcatgcccca
     8341 ttccgatagt caaggcaagg acagcgtgga cttaatcaga gatagcctgt tttccataca
     8401 ggttcagcaa ccgtggctac tgcttcaata caacagttca gacattgaaa gtatcggtat
     8461 tgaccgtgtg gaaagcctgc tctccaccag cccagattcc aacaatggcg aagacagaga
     8521 aaaaattgtt gcggaagaaa ttgaagacag aagcaatacc aatctaacca ttacaaagac
     8581 cattaaccgt ttaggtacag tcttcttcct atttgtcttc aatattggga tttccatatt
     8641 tgtattccta ttaacaggaa tcatgatttt ctcgcaggta ctttttatca tctatgctat
     8701 gtttctgcct gtgagcttta ttttaagcat gattccatca tttgatggta tgtcaaaacg
     8761 agccataaca aagctcttta ataccatttt gacacgagct ggaatcacat tgattattac
     8821 gacagcattt agtatttcaa ccatgctcta taccttatcg gctggttatc cgttcttttt
     8881 gattgctttt ctacagattg tgacctttgc aggaatctac ttcaagctgg gcgatttaat
     8941 gagtatgttt tctctacaga gtaacgattc tcaaagtgtg ggaagtcgtg tgatgagaaa
     9001 acctcgtatg cttatgcacg ctcacatgca ccgtctacag cggaaacttg gacgttccat
     9061 gactactcta ggggctgggt ctgccattgt tacaggtaaa aaaggacagt cgggttcggg
     9121 gagttctgca aggacacaag cagatcactc ccgaccagac ggaaaggaaa aatcaacact
     9181 tggaaaacgt atcggtcaaa ccatcggtac agtagctgat accaaagaca gaatggtaga
     9241 cactgctagt ggtttgaaag aacaggttaa agatttgccg accaatgcaa gatatgcagt
     9301 atatcaagga aaatccaaag taaaagagaa tgtccgtgat ttaaccagta gtatttctca
     9361 aaccaaagcg gacagagcca gtggacgcaa ggaacagcag gaacaaaggc gaaaaaccat
     9421 tgcgaagcgt cgctctgaaa tggaacaggt caaacagaaa aaacagcctg cttcttctgt
     9481 tcatgaaaga ccgactacaa gacaagaaca atatcatgat gaacagacct caaaacagtc
     9541 taatattcag acttcatata aggaatctca acaagccaaa caagagcgtc cagcagttaa
     9601 gtccgatttt tcaagtccaa aagtggaacg ccaaggcaat accgttcaag aaaaaaccgt
     9661 tcaaaagcca gcaacttcaa ccactacagc agatagaact tcacaacgtc caatcacaaa
     9721 agaacgtccg tctactgttc aaagagtacc actacaaaat acaagaagta gaccaccaat
     9781 caaaaccgcc accattaaga aagtcggtaa gaaaccatga agttgaaaac tttagtgatt
     9841 ggtggttctg gattattctt gatggtcttc tcactgcttc tgtttgttgc cattttattt
     9901 tcagatgaac aggacagcgg aatttccaat attcattatg gaggtgtgaa tgtttccgca
     9961 gaagtgctgg ctcataagcc tatggtagaa aaatatgcca aagaatatgg cgttgaagaa
    10021 tatgtcaaca tacttcttgc gattatacag gtggaatcgg gcggtactgc ggaagatgtt
    10081 atgcagtcct cggaatccct cggtcttcca cctaattcat tgagtacaga agaatccatt
    10141 aagcaaggtg tgaagtattt cagtgaatta ttagccagta gcgaaaggct cagtgtagat
    10201 ttagaatcgg ttatccagtc ctacaattat ggtggtggtt tcttagggta tgtggctaat
    10261 cgtggaaata aatatacctt tgaactggct caaagtttct caaaagagta ttcaggtggc
    10321 gaaaaagtgt cttaccccaa tcccatagcc atacctatca atgggggctg gcgatacaac
    10381 tatggcaata tgttttatgt gcaactggta acgcagtatc ttgtcacaac agagtttgat
    10441 gatgatacgg tacaagccat catggacgaa gcactgaaat atgagggctg gcgatacgtt
    10501 tacggtggag cttccccgac tacttctttt gattgtagcg gactgacaca atggacgtat
    10561 ggaaaagctg gaattaactt accacgaacc gcacaacagc aatatgatgt gacccagcat
    10621 atcccactat cggaagcaca agctggcgat ttggttttct ttcattctac ctataacgct
    10681 ggctcttata ttactcatgt tgggatatac cttggcaata accgtatgtt tcatgcaggc
    10741 gacccaatcg gttatgccga cttaacaagc ccctactggc aacagcattt agtgggagca
    10801 ggacgaatca aacaatgaga aaggaagatt taatgatgaa atttagaaaa aatcagaata
    10861 aagaaaaaca gataccaaag gaaaagaaac ctcgtgtcta taaggtcaat cctcataaaa
    10921 aggttgtgat tgccttgtgg gtacttttag ggcttagttt cagctttgcg atattcaagc
    10981 actttacagc tatagatact catactattc acgaaacaac tatcatagaa aaggaatacg
    11041 ttgatactca tcatgtagaa aattttgtag agaactttgc gaaagtctac tattcatggg
    11101 agcaatccga taagtccatt gataatcgaa tggaaagtct aaaaggctat ctgacagatg
    11161 aacttcaagc tctcaatgtt gatacagtac gcaaagatat tcctgtatcg tcttctgtaa
    11221 gaggatttca gatatggacg gtagagccaa ctggcgacaa tgagtttaat gtaacctaca
    11281 gtgtagacca gctcattaca gagggagaaa atacaaagac cgtccactct gcttatatag
    11341 tgagtgtcta tgtagatggt tctggaaata tggtactggt taagaatccg accattacca
    11401 acatacctaa gaaatcaagt tataaaccaa aagccattga aagtgagggg acggttgatt
    11461 ccattacaac caatgaaatc aatgagtttt taacgacgtt cttcaagctc tatcctacag
    11521 cgacagccag tgaactttcc tactatgtga atgacgggat attaaaacca atcggaaaag
    11581 agtacatctt tcaagaactg gtaaatccta ttcacaatcg taaggataat caagtcacgg
    11641 tatcgctgac agtggagtat atcgaccagc agaccaaagc aacgcaggta tctcaatttg
    11701 atttggtact tgaaaagaac gggagtaatt ggaagattgt aaaataacaa atattggtac
    11761 atgattacag atactttgta atcatgtact ctttttgata aaaaattgga gattccttta
    11821 caaatatgct cttacgtgct attatttaag tgactattta aaaggagtta ataaatatgc
    11881 ggcaaggtat tcttaaataa actgtcaatt tgatagcggg aacaaataat tagatgtcct
    11941 tttttaggag ggcttagttt tttgtaccca gtttaagaat acctttatca tgtgattcta
    12001 aagtatccag agaatatctg tatgctttgt atacctatgg ttatgcataa aaatcccagt
    12061 gataaaagta tttatcactg ggatttttat gcccttttgg gtttttgaat ggaggaaaat
    12121 caaatgaaaa ttattaatat tggagtttta gctcatgttg atgcaggaaa aactacctta
    12181 acagaaagct tattatataa cagtggagcg attacagaat taggaagcgt ggacaaaggt
    12241 acaacgagga cggataatac gcttttagaa cgtcagagag gaattacaat tcagacagga
    12301 ataacctctt ttcagtggga aaatacgaag gtgaacatca tagacacgcc aggacatatg
    12361 gatttcttag cagaagtata tcgttcatta tcagttttag atggggcaat tctactgatt
    12421 tctgcaaaag atggcgtaca agcacaaact cgtatattat ttcatgcact taggaaaatg
    12481 gggattccca caatcttttt tatcaataag attgaccaaa atggaattga tttatcaacg
    12541 gtttatcagg atattaaaga gaaactttct gccgaaattg taatcaaaca gaaggtagaa
    12601 ctgtatccta atatgtgtgt gacgaacttt accgaatctg aacaatggga tacggtaata
    12661 gagggaaacg atgacctttt agagaaatat atgtccggta aatcattaga agcattggaa
    12721 ctcgaacaag aggaaagcat aagatttcat aattgttccc tgttccctgt ttatcacgga
    12781 agtgcaaaaa acaatatagg gattgataac cttatagaag tgattacgaa taaattttat
    12841 tcatcaacac atcgaggtcc gtctgaactt tgcggaaatg ttttcaaaat tgaatataca
    12901 aaaaaaagac aacgtcttgc atatatacgc ctttatagtg gagtactaca tttacgagat
    12961 tcggttagag tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat
    13021 ggtgaattat gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag
    13081 tttttgaagt taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt
    13141 gaaaatccgc accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa
    13201 atgttgcttg atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg
    13261 gattctacga cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt
    13321 agtgcactgt tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt
    13381 tatatggaga gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat
    13441 cctttctggg cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag
    13501 tatgagagct cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa
    13561 gggatacgct atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc
    13621 tgttttaagt atggcttata ctatagccct gttagtaccc cagcagattt tcggatgctt
    13681 gctcctattg tattggaaca agtcttaaaa aaagctggaa cagaattgtt agagccatat
    13741 cttagtttta aaatttatgc gccacaggaa tatctttcac gagcatacaa cgatgctcct
    13801 aaatattgtg cgaacatcgt agacactcaa ttgaaaaata atgaggtcat tcttagtgga
    13861 gaaatccctg ctcggtgtat tcaagaatat cgtagtgatt taactttctt tacaaatgga
    13921 cgtagtgttt gtttaacaga gttaaaaggg taccatgtta ctaccggtga acctgtttgc
    13981 cagccccgtc gtccaaatag tcggatagat aaagtacgat atatgttcaa taaaataact
    14041 tagtgtattt tatgttgtta tataaatatg gtttcttgtt aaataagatg aaatattttt
    14101 taataaagat ttgaattaaa gtgtaaagga ggagatagtt attataaact acaagtggat
    14161 attgtgtcct gtatgtggaa ataaaacacg attaaagata agggaagata ctgaattaaa
    14221 aaaattcccc ctctattgtc cgaaatgcag acaagaaaat ttaattgaaa taaagcagtt
    14281 caaagtaact gtgattacag agccagacgc aaagacgcag agccgataaa atgagattaa
    14341 tacaatctca ttttatcggc tctttccgtt atgtatggat tcttttaatt agtcttcgat
    14401 gtttcttgct tcgttgatac cgctggctaa agattccatt aaggatagtt ctttgtctgt
    14461 aaagctatcc atgtatttct ctatctgtaa tcgtcgggtg ctttttacca agttattagc
    14521 aggtaagaaa aattcatcaa cggaaacatg aagtaacgat acaaggtcat aaagaacttg
    14581 tatgctgggg tgttgccctt tattttcaat attagttaag taccgtgggt caatttcaat
    14641 caatgctccc acttgttcac gagttaaacc tcgtttcaat cgagcttctt taatggctaa
    14701 accaaaggct ctaaaatcat atttatcttc ttttttacgc atagtagacc acctctatac
    14761 attttattgt tcctactgaa ttaaaaacag gtatagaaaa acgtgttata tggtttatag
    14821 gtttatattt aataaaaagc actactaaac gccaataaaa aaaaccgtta tatggtagtg
    14881 ctatttacgc tgttaaaata ttgtatatta cttccaaatg gcggtttgtt ggaggtcaac
    14941 gtcgccatga agtacatcat atacaataaa tttccttaca ttgggttctt gtcaaaaaaa
    15001 gtcgtctatc tgcaatagat aagtacgtcc accaatgtgg ttttataaat catatagata
    15061 gaataacaga agcatgtaaa cagagaaata aatctgttta tatgcttttt tggctattca
    15121 gaactttttt acaaagttta tttatcagta atgcaacaaa tccccctttc acattgggac
    15181 taagagtgaa aggagataaa cgagcaaggc tcacttcctt tcctagacag aaagggggtg
    15241 agaaacatga aaccatcttc ttttcagacc acaatagaaa atcagtttga ctatatctgt
    15301 aaacgtgcta tggaagacga gcgaaagaat tatatgcttt atctttcaag gattgcaaag
    15361 cgtgaggtgt ccttttcgga tgttggcgat tatcttgtta gccagtttgc gacaacagat
    15421 aactattcaa ctgactttca gatttttaca ctcaatgggt tatcagtagg cgttgaaaat
    15481 gatttgttga gtgaagcatt acgtgagttg ccagacaaga aacgtgaaat tctactgctg
    15541 ttttacttta tggacatgag cgattcagaa attgcagacc tgttgaaatt gaaccgttct
    15601 actgtctatc ggcatagaac cagtggacta gccttaatta aaaagtttat ggaggaattt
    15661 gaagaatgaa aacacaatat cctatgattc cctttcctct cattgtaaag gcaacagatg
    15721 gcgataccga agcgattaac cagattctac atcattacag agggtacata acgaagcgtt
    15781 ccctacgact tatgaaagat gaatatggca atcaaagtat ggtcgttgat gaagtcttac
    15841 gtggaagaat ggaaaccaga ctgattacaa agattttgtc atttgaaatt aagtaatatc
    15901 ctctctcctt tcgtggaagc gtgctaaacc attccacgct tcccgaacag ggaggtttgt
    15961 tattccacca aagcatattg agctttcaat gtgttttgat aggctaacga gccattgttc
    16021 tttgaaaact gaataaaagt aatcgaatac gtttcgataa gaaaagagcc aacggaacta
    16081 accgccatga cctatcttat aaagatagcg agcgattcat gttagtgatc cgagaagcaa
    16141 tctttagcag gattgcctgc aacgacattc ttatcgtgat aatgatactc ccatacagtc
    16201 aatagtccga gcgtgataaa accgtcgcag gcaatgagta tggctacatg agaaccatgc
    16261 aggggtggaa ctcccgtgag ctttgctaaa gctgttcgat tgctggtaaa acaactttta
    16321 tgaaatccaa ataagtgatt tggaaaggag gattttatga agcagactga cattcctatt
    16381 tgggaacgtt ataccctaac cattgaagaa gcgtcaaaat attttcgtat tggcgaaaac
    16441 aagctacgac gcttggcaga ggaaaataaa aatgcaaatt ggctgattat gaatggcaat
    16501 cgtattcaga ttaaacgaaa acaatttgaa aaaattatag atacattgga cgcaatctag
    16561 cgtcgccaaa gggtcttgta tatgataaaa tagtattaag tcgtatcaag gctctttcca
    16621 taaaggaaag gagcaaatgc catgtcagaa aaaagacgtg acaataaagg tcgaatctta
    16681 aagactggag agagccaacg aaaagacgga agatacttat acaaatatat agattcattt
    16741 ggagaaccgc aatttgttta ctcgtggaaa cttgtggcta cagaccgagt accagcagga
    16801 aagcgtgatt gtatctcact tagagagaaa atcgcagagt tacagaaaga cattcatgat
    16861 ggtattgatg ttgtaggaaa gaaaatgaca ctctgccagc tttacgcaaa acagaacgct
    16921 caaagaccaa aggttagaaa aaacactgaa actggacgca aatatcttat ggatattttg
    16981 aagaaagaca agttaggtgt aagaagtatt gacagtatta agccatcaga cgctaaagaa
    17041 tgggctatta gaatgagtga aaatggttat gcttatcaaa ccatcaataa ctacaaacgt
    17101 tctttaaagg cttcattcta tattgctata caagatgatt gtgttcggaa gaatccattt
    17161 gactttcaac tgaaagcagt tcttgatgat gatactgtcc ctaagaccgt actaacagaa
    17221 gaacaggaag aaaaactgtt agcctttgca aaagctgata aaacctacag caaaaattat
    17281 gatgaaattc tgatactctt aaaaacaggt cttcgtattt cagagtttgg tggtttgaca
    17341 cttccagatt tagattttga gaatcgtctt gtcaatatag accatcagct attgagagat
    17401 actgaaattg ggtactacat tgaaacacca aagaccaaaa gtggcgaacg tcaagttcct
    17461 atggttgaag aagcctatca agcatttaag cgagtgttag cgaatcgaaa gaatgataag
    17521 cgtgttgaga ttgatggata tagtgatttc ctctttctta atagaaagaa ctatccaaaa
    17581 gtggcaagtg attacaacgg catgatgaaa ggtcttgtta agaaatacaa taagtataac
    17641 gaggataaat tgccacacat cactccacat agtttgcgac atacattctg taccaactat
    17701 gcaaatgcag gaatgaatcc aaaggcatta cagtacatta tgggacatgc taatatagcc
    17761 atgacgctga actattacgc acatgcaaca ttcgattctg caatggcaga aatgaaacgc
    17821 ttgaataaag agaagcaaca ggagcgtctt gttgcttagt agtacaaatg aatttactac
    17881 ttatttacca cttctgacag ctaagacatg aggaaatatg caaagaaacg tgaagtatct
    17941 tcctacagta aaaatactcg aaagcacata gaataaggct ttacgagcat ttaagaaaat
    18001 ataaaaagat aattagaaat ttatactttg ttta
//
LOCUS       DAMKOJ010000249        15611 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.088, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000249 DAMKOJ010000000
VERSION     DAMKOJ010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.088"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..153
                     /locus_tag="PC592_003841"
     CDS             <1..153
                     /locus_tag="PC592_003841"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057719.1"
                     /translation="GNSGGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGA
                     NIGKTE"
     gene            261..998
                     /locus_tag="PC592_003842"
     CDS             261..998
                     /locus_tag="PC592_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF4057720.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTRLNEENFSIKLFKADVSNREDVENMVDYCIKEFGGLDVLVNNAGISQDKLFTDITD
                     VDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDILVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            1096..1980
                     /gene="rsgA"
                     /locus_tag="PC592_003843"
     CDS             1096..1980
                     /gene="rsgA"
                     /locus_tag="PC592_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF4057721.1"
                     /translation="MLEGKIIKGISGFYYVDTHNGIYECKARGIFRKHKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKKIYELSGYKVIPVSNITKLNIEKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVANGEISKERY
                     ESYIQLLNEIRQNNSRRY"
     gene            1985..2656
                     /locus_tag="PC592_003844"
     CDS             1985..2656
                     /locus_tag="PC592_003844"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF4057722.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPIDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVDKVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            2665..3306
                     /locus_tag="PC592_003845"
     CDS             2665..3306
                     /locus_tag="PC592_003845"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF4057723.1"
                     /translation="MKICIVLNGEIEDYEVTRGIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     KGDAKGVTLTGLEYPLDNYYMRYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            3437..4066
                     /locus_tag="PC592_003846"
     CDS             3437..4066
                     /locus_tag="PC592_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF4057724.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIDLSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERNNLLNECSLKECEYLSENGAKLFDDIENTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFVDFECPGNTGLHKGENNKLIIERNKLKNPI
                     YIGDTQGDANSAKFAGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            4121..4777
                     /locus_tag="PC592_003847"
     CDS             4121..4777
                     /locus_tag="PC592_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF4057725.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVIIKRRDLMEKIADVITKKQQEILVEMEKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            5172..5894
                     /locus_tag="PC592_003848"
     CDS             5172..5894
                     /locus_tag="PC592_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012422616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4057726.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIIDIMMPKMDGITLTMKLRENHNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVENKEQKVDDDDGVFAIGGLELNENTKEVSVDG
                     KHIKATPIEFKILSLLMRNAGRVFSADEIYERVWNDNAVNTDTVMVHVRNIREKIEVD
                     PKNPKYLKVVWGVGYKIEKIQR"
     gene            5863..8196
                     /locus_tag="PC592_003849"
     CDS             5863..8196
                     /locus_tag="PC592_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF4057727.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVDNMYKGSYVLYHNMKEEQEGKMIQPSKLFISKETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNQNFENWESFIKESGKNLKYYLVDKESNFEFFNDNKELGALD
                     TTKNYASKEDSDENKSKNTEMSDEERQKQIKDIKENYRFYIVMNFDKDGKVNVLDSYG
                     VNQKVISQMLLSKAREDLMNTTLGGNPISYKLSPIKNVTLVYAVPKVISKGDGGEYSY
                     GNIYNNDSISSYINNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIILAILQGIVDLYPTSIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIKEYFIKNTVTGMFFVWLIKSGKVVINQIRITDLK
                     EKPNKTIAIILGINLLIIVIMCSFWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLEVNMERDLGFFNPIKDELGNIQAGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKVNSGD
                     VHLNIMNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVSIMLKNMSATEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(8475..11153)
                     /gene="mngB"
                     /locus_tag="PC592_003850"
     CDS             complement(8475..11153)
                     /gene="mngB"
                     /locus_tag="PC592_003850"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF4057728.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRKKLAIGPWYTQTDQLVISGESIVR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDTIGKLKVKSSTNNVYFPNG
                     FDQAPIRKNLPDILKKANKIDTENEYEISDIENYVDSVRNERNEFTELKGEFVNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLILKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDFHMRLISTQIKNNNEEITLTVFNGL
                     PEARNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITDYILTQTIKLNPSKKIYI
                     PKTVYRAKIALSVKNIPPMGYTQLIVELDTKNKCEIKTSSCKKIENKYYKITANKNGS
                     VEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNVQEE
                     MTLKYSLTIPASLEERTIGKVSVKMPVTMKITLEPKEQIIKFNINIKNDQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTALEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQKGVALITGCVREYQIVGANLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFNFGLYIYNNKFDKSNIANTAKRFLTPIQIYEYADFLNGRLIFVFNDEKQ
                     IYENEYSFMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDSKGSLNINKNINAAYN
                     AMLDEIYDNTNKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(11227..12333)
                     /locus_tag="PC592_003851"
     CDS             complement(11227..12333)
                     /locus_tag="PC592_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF4057729.1"
                     /translation="MSKKNNSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPSMGAGFIGGL
                     IASNTNAGFLGAVTAGFFAGYICKFLKKKIKISGSAAGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGSMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSRFSKTLSETGKGNIVMGIIGITEGAI
                     PFTLKNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISVGSGWAYLVGAIF
                     GALVIAILSTILVDFNEDETAENTEFDEIELDIM"
     gene            complement(12448..12756)
                     /locus_tag="PC592_003852"
     CDS             complement(12448..12756)
                     /locus_tag="PC592_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF4057730.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHKIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGVALKKPEAVLTKCIETIS
                     "
     gene            complement(12759..13211)
                     /locus_tag="PC592_003853"
     CDS             complement(12759..13211)
                     /locus_tag="PC592_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF4057731.1"
                     /translation="MVLQEKNIFIDKDLKSKEEVLNFIADSAYILGITTNKDALLKDL
                     LKRESEFPTGIRDGFAIPHTKSANVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HENEGNIHLKTLSKLATCLMEDDFISEVKNASDASHLVKYITNKMKEE"
     gene            13446..15374
                     /locus_tag="PC592_003854"
     CDS             13446..15374
                     /locus_tag="PC592_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF4057732.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSINE
                     TLEKNGAIIKIKKGEGYYIDILNLALYQHYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQKIVLSEINKFNINFLDFNLK
                     NFIIHLSITISRILGGYCLDNVLDVVLTDFQSNTAVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRADTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEISLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSRIYSNLLDNFFDKNLF
                     IVNPKIKEKDELIKLMCNKLTQSEIVIPSFTESVFYRESLSSTNIDDFLAIPHPMELS
                     SIKTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDSFLSIIKSII"
BASE COUNT         5797 a         1837 c         2429 g         5548 t
ORIGIN      
        1 gggaactcag gaggctcaaa ttcaggagac aatggaggga gctcaggcgg ttcaaactca
       61 ggagacaatg gagatagttc aggaggctca aactcaggag ataatggagg aacttcatca
      121 ggcactggtg caaatattgg taaaacagaa taaatattaa taaaataaga gctgtccttt
      181 tatagaaaat attttcttta aagggcagtt tgttttgtat aaaatattga attggttata
      241 atataaggag aaaagcattt atgaaaaaga aaacagtttt aattacagga ggagctagag
      301 gaattggcaa agctatgtct aaagcttttg caaaagaagg ttataatgta ttagtaaatt
      361 ttaataagtc agaaaatgaa gctaaagagt tgtatactag attaaatgaa gaaaattttt
      421 ctataaaact ttttaaggct gatgtttcaa atagagaaga tgtagagaat atggtagatt
      481 attgtataaa agaatttgga ggattggatg tacttgtaaa caatgctggt ataagtcaag
      541 acaagttgtt tacagatata actgatgtag actgggataa tatgatgaat attaatttaa
      601 aaggaagttt ttattgttca caagttgctt taaaatacat gatatcagaa aaaaaaggaa
      661 atataattaa tatatcttca atctggggta tatcaggtgc ttcttgtgaa gtgcattatt
      721 ctataacaaa agcaggtata ataggaatga caaaagcatt agctaaagaa gtaggaccat
      781 caaatattag agtaaatagc atagctccag gtgtcattaa tactgatatg ttatctggat
      841 ataatgagga agatatagat attcttgtgg aagaaactcc tctaatgagg ctaggaactc
      901 cagaagatat agcaaattgt gctattttct tggcatcaga caaatcaaat tttataactg
      961 gtcaagtaat tagtccaaac ggaggatttg ttatttaaaa aaaatgtggt attatataaa
     1021 aataggaaag aataacacga tatactactc ataaacagta tgtgtttata taaattttat
     1081 aaagggaggc atttgatgct agaaggaaaa attataaagg ggattagtgg attttattat
     1141 gtagatacgc ataatggtat ttatgaatgt aaggctagag gaatatttag aaaacataaa
     1201 ataacacctc tggttggtga tagagtcaaa ataagcattg ttgatgagga tgaaaaaaaa
     1261 ggtatcttag aagaaataga cagtagagat acagaactta taagacctcc tatagcaaat
     1321 gtagataagg cactaatagt attcgcaata aaaaatccta aaccaaactt atctctttta
     1381 gatagattta tagttttggc agaaaaagaa aatttagaaa ctgtaataat ccttacaaaa
     1441 gcagatttag atgataatga tacactagaa actgttaaaa aaatatatga acttagtgga
     1501 tacaaagtta ttcctgtaag caatattact aaattaaata tagagaaagt aaaagaagag
     1561 ttaaaagaaa atgtagtagt gtttgcagga ccatctggag ttggaaaatc aagtttacta
     1621 aatgaaatag atgaaaactt taaacttcaa acaggagtgg taagtgataa aataaaaagg
     1681 ggaaaacata ctactcgtca tgctgaactt ttaaaattgg aatttggtgg aatggttgca
     1741 gatacaccag gctttagttc tcttgcactt gaagatatag aggaagttga acttaaagat
     1801 tattttatag aatttgataa atttaatgat tgtaagtttg gttcaaaatg tattcatgaa
     1861 aatgaaccta attgtgctat aaaagaagct gttgcaaatg gagaaatatc taaagaaaga
     1921 tatgagagtt atatacagct actaaatgaa ataagacaaa ataatagtag gaggtattag
     1981 aaacatgatt aaattagcac catcaatatt atcagcagat tttgcaaaat tattagagga
     2041 tgtaagaaag gtagagagtg caggatgtga atatcttcat atcgatgtaa tggatggaca
     2101 ctttgtacca aacattacat taggaccact tgtagtcaaa agtttgaaga aagaaaatat
     2161 aaatatggta tttgatgctc atcttatgat agaaaatcca gaccagtata ttgaagagtt
     2221 tgtaaaagca ggatgtgata taataactgt tcatcaagag gcttgtgttc atctacatag
     2281 aactatacaa aatataaaat cacatggaat aaaagcaggt gtagtgctta atccagctac
     2341 accaatagat actattaaac atgtactacc tgatttagat atggtattat taatgtctgt
     2401 taatcctgga tttggaggac aatcatttat accttgtgtt ttagataaga ttaaagagtt
     2461 aaaagctatt atagatagtc aaggattaaa tattgatata gaagttgatg gtggtataag
     2521 ccctaaaaat gtggataaag ttgtacaagc aggagctaat gtaatagtag caggttctgc
     2581 aatatttgga agtgatgaca ttcaagaaac agttaattta tttagaaaga atgcttctct
     2641 tgaagaatta gtttaaattt aagaatgaaa atctgtattg ttttaaatgg tgaaatagaa
     2701 gattacgaag ttacaagagg tattataatt aaagaatgtt atgactgcat aatatgtgca
     2761 gatggaggag caaatcacac ttataaaatg gaaataatgc cagattatat attaggagac
     2821 ttagattcag tagaagaaga aaagataaac ttctataaaa ataaaggtgt taaatttgaa
     2881 aaatttccat ctaaaaaaga tgagactgat acagagcttt gtcttttttt agctaagaca
     2941 cttaaagcaa atcatattga tttttttggt gctttaggag gtaggattga ccacactctt
     3001 gcaaatataa agctattata ttatttaaaa gaagatggta tatattctag gatactttct
     3061 gataaagaag agatgtatat agttgaaaat gaagaaattt cactgtatgg aaatccagga
     3121 gacactattt ctgtaatagc tataaaaggt gatgctaagg gtgtaacact taccggatta
     3181 gaatatcctc tcgataatta ttatatgaga tactctgtac ctattggaat atcaaatgtt
     3241 atgttgagta attcttgtaa gattaaagta gagcaaggat gtgtacttgt agttagaaat
     3301 ttataaaatt tggttttgac aattgatttt atattgtaga gcagatacaa tcaagtaaaa
     3361 tatatttatg attgtatctg ctttttagta tataattata aatagataat aaactttgac
     3421 ataaggggga ttttttgtgg tagatagtat tatttttgat ttagatggaa cgttgtggga
     3481 ttcaactgaa gaagtatgca aagtttggca ggatgtttta agtaaacata aagaaataga
     3541 tttaagtgtc acaaaagatt tatttagaag tcttatgggg ctttcttttg aggaaatagc
     3601 aaatcgttta tttccaaatt taagtgaaga agaaagaaat aatttattaa atgaatgttc
     3661 tttgaaagaa tgtgaatatt tatctgaaaa tggagctaaa ttatttgatg atatagaaaa
     3721 tactcttaaa ttactatcta aaaaatataa attatttata gtaagtaatt gtcaagctgg
     3781 atatatagaa tcttttttaa aagcacataa actagaacag tattttgtag attttgaatg
     3841 tccaggtaat actggtttgc ataaagggga aaataataaa cttataattg aaagaaataa
     3901 attaaaaaac ccaatctata ttggagatac tcaaggtgat gcaaatagtg ctaagtttgc
     3961 aggtatccct tttatatatg ctaaatatgg atttgggaat gtagatgtat atgattattt
     4021 tatagactca tttaaagatt tgttagaaca tgatatatta aaataggatg agtttaaaaa
     4081 ttatattaaa ataataaaaa agttatgggg ggatttaaaa atggaattac aggatactat
     4141 ttttaaaaga caaagtgtaa gaaagtttaa aaatcaagat gtgtcagatg aagatatttt
     4201 aaaaatgata aaagcagcag gtgcagctcc atcaggaaag aatattcaaa actggcattt
     4261 tgtcattata aaacgtcgtg acttaatgga aaagatagca gatgtgataa ctaaaaagca
     4321 acaagaaata cttgtagaaa tggaaaaagt atcagtagat aaggctaata gatttagaaa
     4381 atttgttaaa aactttacac tattttactt aaaagctcca gttttagtat tagtttttac
     4441 aaaggtatat aatccatcag gatattatga attagagctt atagatgcac ctaaggaaac
     4501 tatagataaa ttattcataa gaaatccagg tatgcagagt ttaggtgctg cgattgaaaa
     4561 ctttacatta tcagcaattg aacttgggta tggttcttgt tggttgacaa gtcaaaacta
     4621 cgcagcagat gaaatagaag ctgttttaga agcagaaact ggatttgaaa aaggagagta
     4681 ttttttaggt gcaatgttgg ctcttggagt gccagaggat aatttgaaga gcccatctaa
     4741 aaaaccagta gaagaaatat gtacatttat aaaataaaag acaataattt ttaagattca
     4801 aaatgagtta aaaataaata gttaaaaata aaaaggtagg ttttattgat attaagttta
     4861 tgtttcaaat cattgattta attaatgcaa taaaaactac cttttttgtg catattaatt
     4921 ttgaataact ccaaatcttt agaaaatctt tagaaaagta tatgtaatat cttaagtttt
     4981 taactttaat attaagtata taaaatgaaa aaactaaatt tatactagag ggaggtctct
     5041 aaggtgtaca ttaaataaaa ataactatta gaaagatata aatatataaa aaaatggaaa
     5101 aacttctatc atattgtata atcatatatg taaagaaaat ttataaatta attggtataa
     5161 aggagattaa aatgaattca tataatattt tggtggtaga agatgaaaag gaaatagcag
     5221 atgctataga gatataccta ttaaatcaag gatataatgt ttttaaagga tacaatggat
     5281 tagaaggact taaggttata gaaaatcaag aaatacattt agcaataatt gatataatga
     5341 tgcctaaaat ggatggaata acacttacaa tgaagcttag agaaaatcat aatttcccag
     5401 taataatgct atctgcaaaa tcagaagaag ttgataaaat aatggggctt aatatagggg
     5461 cagacgatta tgtaacaaaa ccttttaagc ctttagagct attggctaga gtaaactcac
     5521 aacttagaag atacactaag tatttaaata tggttgaaaa taaagagcaa aaagtagatg
     5581 atgatgatgg cgtgtttgca ataggtggat tagaattaaa tgaaaataca aaagaagtta
     5641 gtgttgatgg gaagcatata aaagcaactc ccatagaatt taaaatacta agcttactta
     5701 tgagaaatgc aggaagagtt ttttctgctg atgaaatata tgaaagagtt tggaatgata
     5761 atgctgtaaa tacagataca gttatggtac atgttaggaa tataagggag aaaatagaag
     5821 tagacccaaa aaatcctaaa tatttaaagg tggtgtgggg tgttggatac aaaattgaaa
     5881 aaattcaaag ataaatatat agttactatt atagttttta tacttatgtt atcagcatca
     5941 ttaggtatga ttagtcaata ttctactatt caagcagggg ctaaaggtgg agcaaagaat
     6001 ccatttgaac aggaaagttt tgtagataat atgtataaag gaagttatgt tttatatcat
     6061 aacatgaaag aagaacaaga aggtaagatg atacaaccct caaaactttt tataagtaaa
     6121 gaaactatga actatataaa aaatgtaagt aaagaaaaag atacttatga tggctcagag
     6181 acttattata cagatgatag tattaatgca gattttaatc aaaactttga aaattgggag
     6241 tcttttatta aagaatcagg aaaaaattta aaatattatt tagttgataa agaaagtaac
     6301 tttgaatttt ttaacgataa taaagaatta ggagcacttg atacaacaaa gaattatgct
     6361 tcaaaagaag attctgatga aaataaatca aaaaatacag aaatgagtga tgaggaaaga
     6421 caaaagcaga ttaaagatat aaaggaaaac tatagattct acattgtaat gaattttgat
     6481 aaagatggaa aagtaaatgt tttggattct tatggagtaa atcaaaaagt tattagtcaa
     6541 atgttattgt ctaaagcaag agaagattta atgaatacaa ctttaggtgg aaatccaatt
     6601 tcatataagc tatctccaat aaaaaacgtg acattagtat atgcagtacc taaggtaata
     6661 agtaaagggg atggtggaga gtatagttat ggaaatattt ataataatga tagtataagt
     6721 tcatatataa ataatgtaga aaataattct tactataaga tttctggaat gattttaaaa
     6781 attatattag ctatagttgt gattgtagct ttagcattcc catatagaaa atctaaagaa
     6841 ttactaggat ttgatacatt atcaagaata ccattagaga tattatttat tattcttgct
     6901 attttacaag gaattgtaga tttatatcct actagtataa taagtaatac tttgagtgga
     6961 aattatgtag aatatctgat aaacaatgac ataagtgcta aaatggctag tatattggta
     7021 agtttaatga atctaactta ttggtttgta atattctcaa taatatttgt atttataata
     7081 cttttaaaac atattttaaa tgttggaata aaagagtatt ttataaagaa tactgtcaca
     7141 ggaatgtttt ttgtatggtt gataaaatca ggaaaagtag ttattaatca aattagaata
     7201 acagatttaa aagaaaagcc taataaaact atagctataa ttttgggaat aaacttatta
     7261 attatagtta taatgtgtag tttttggttc tttggaataa tacttgcatt gatatattca
     7321 gtagtattat ttaagatatt gtcagattac tctaaaaaga caatatatga atataatcaa
     7381 cttttagatg ttacaaagaa aatttcagat ggaaacttag aagtaaatat ggaaagagat
     7441 ttaggatttt ttaatcctat aaaagatgaa ttaggaaata ttcaagctgg atttaaaaaa
     7501 gctgttgatg aagaggttaa gagtcaaaag atgaaaacgg agcttatatc aaacgtatca
     7561 catgacctaa aaacacctct gacatctata atcacttata tagatttatt aaaagatgaa
     7621 agtataacag atgaaaatcg taagttgtat attgatacat tagatagaaa gtcacaaaga
     7681 ttgcaacatc taatagaaga cttattcgaa gtaagtaagg taaatagtgg agatgttcat
     7741 ttgaacataa tgaatgtgga tattgtgtct ctaatgaaac aaacactttt agaattagat
     7801 gacaaacttg cagattcatc tctaatagta aagaataact tttctaatga aaaaataata
     7861 ttaccattag atagtcagcg tacatttaga gtatttgaaa atcttataat aaatataagc
     7921 aaatatgcaa tgccaaattc aagagtgtat attgatattt tagaaacaga caataaagta
     7981 agtattatgc ttaaaaacat gtctgcaact gagattgatt ttagtgtaga tgatataatg
     8041 gaaagatttg taagaggaga taagtcacgc aacacagaag gttctggtct tggtttagca
     8101 atagcaaaaa gttttataga attacagggt ggtaagatga atataagtgt ggatggtgat
     8161 ttatttaaag ttacaattac ttttaataaa aattagaata gacttcttta ataattataa
     8221 aatccataaa ataatatttt ataggtattg ttttaaagta gtttttaaac attatttcaa
     8281 aacaacttgt aaatcttatt ttaaaataga atgttgattt atttaaaaaa ggtgaatcct
     8341 aatatataag attcaccttt ttattttata aaatgttact tagtgttata gatattttaa
     8401 atagtgtaaa tttggattta ccattaacat aaggttagta atttcttttg aaatcttgta
     8461 taagctattt tatattattt aattactatt gtttgtactt tacaatgtga caaagaattt
     8521 acttctacag ttttagtatt taccttaagc ttgttagtat tatcatagat ttcgtcaagc
     8581 attgcattat aagcagcatt gatattttta ttgatgttaa gacttccttt agaatcctca
     8641 tttttcatac cattgaagat tctaactaca attccgtctc ctttttcttc tttctttatt
     8701 gcacttactg tgaaatttga attatttaca ttcataaaac tatattcatt ttcatatatt
     8761 tgtttttcat cattaaatac aaatataagt ctaccattta aaaaatcagc atattcatat
     8821 atttgtatag gtgttaagaa tctcttagca gtattagcta tatttgattt atcaaattta
     8881 ttgttgtaga tgtaaagacc aaagttaaag tttaactctt tgagtaattg tgcatctggt
     8941 gttgctatta ttttttctcc agaagctctt cctggtctat aaagtaaatt ttctcttccc
     9001 atatatccaa atgacctaaa tagtgttaat gctattgtat ctaaattagc accaactatt
     9061 tgatattctc tcacacaacc agttattaat gctactcctt tttgtccatc ttctaaagta
     9121 acaaaacttt gcattggttc aatagttata ggcttttctt gccatgagta attgtctctt
     9181 ttccataatg caaggtcttt ttctaatgct gttggtcttt gtattattcc aaattgttga
     9241 tctgctatag aaaacttaga tgctatttcc gtattaaata aaactcttac tctatgagat
     9301 aatgcttggt cattttttat attaatatta aacttaatta tttgctcttt aggttctaag
     9361 gtgattttca ttgttactgg cattttcaca gaaactttac ctatagtcct ttcttctagt
     9421 gaagctggta tggtcaatga atatttaagt gtcatttctt cttgaacatt tgattttagc
     9481 acttctactg aagatacaga atctaaagat gaaacataaa tatcttttct tggaggcgaa
     9541 tagttgtatg aatctccatc atctccatta tcttcaatta cagcttggtt tttataagtc
     9601 ttattagact ctttatctaa tatttctact gaaccatttt tattggctgt tattttatag
     9661 tatttgtttt ctattttttt acaactactt gtttttattt cacatttatt tttagtatct
     9721 aattcaacaa ttagctgagt atatcccatg ggtggtatat tttttactga aagtgcaatt
     9781 tttgccctat atacagtttt tggtatatat atttttttac ttgggtttaa ttttattgtt
     9841 tgagttaata tataatctgt aatatcttct ttttctttta ttatataatt aagaatttct
     9901 ccatttttgt tctttatcac aaaatcttga cctggaatat aagtatcaaa ttctacaact
     9961 tcatttctag cttctggtaa tccattgaat actgttaatg ttatttcttc attattattt
    10021 ttgatttgag tacttataag tctcatatga aaatctaaca aatttatact caaatctctg
    10081 gcttgtttgt atcttgtgta tacatcttca tttgttgtgt cactattaca agaacctatg
    10141 ctgtcatgag ctgcattttc gaacataagt ttccatatat cttttaaaat taggtgaggg
    10201 tattcatttc caagtgaata acttaatgtt aataatggtt caagtacatt tgtaatataa
    10261 ttttctaatt tattattcat tatcttaagg tctgaccttg aggagaatat tgatttgtgt
    10321 attctcatat gtttagcatt tacaaattca cctttaagct ctgtaaattc atttctttca
    10381 tttcttactg aatctacata gttttctata tcacttattt cgtattcatt ttcagtatct
    10441 attttattag ctttttttaa tatgtcagga aggttttttc ttattggtgc ttggtcaaat
    10501 ccatttggga aatatacgtt attagtagag gatttaacct taagttttcc aattgtatct
    10561 tttaaatatt cttttaaatc tgaatcatct tctggtatat tacctccata gtaataacca
    10621 aatggtattt gaactgctaa tacctttgag ccatcagaac ctttccatat aaattctgtt
    10681 gtatctacca tatcatcaga aactccacgc caaaataatg aactatctat tccaaaacct
    10741 ctatatattt gtggcatttg agctgattgt ccaaaagaat ctggtacata tccaaccctc
    10801 ataggttcgc caaattcatt gcatctatct attccatagt aaaggtttct aactatagat
    10861 tctcctgata taaccaattg gtctgtttga gtataccaag gtcctatagc taactttttt
    10921 ctttgaacta aatctcttat tctatattca tcctgaggtc tccattttaa ataatcatct
    10981 aagagagaag cttgtgcatc catagtaaag tatttaaagt cttctttttc ttctaatatg
    11041 tctaatatat cttgaaaatc tttcattaga tatatttttg accttgatgt tgtaaaatac
    11101 cattctctat cccaatgact atgtggaact acatgtactt ttgtcttctt cataaaatcc
    11161 tccctaaatt taattgagaa ttgagagtac gctcaattct caactagcta aaattaaatc
    11221 tttaatttac attatatcta actctatttc atcaaattct gtattttccg cagtttcatc
    11281 ttcattaaag tctactaaaa ttgttgataa tattgctatt actaaagctc caaatatcgc
    11341 acctactaag taagcccatc cagaacctac tgatataaat ccatataatc caccaactgg
    11401 aggcattata gcatgtacac ctaataaagc tgataatcct acacccaaag cacatcctat
    11461 catattgaca ggaactaatt ttaatggatt ttttaaagtg aaaggaattg caccttctgt
    11521 tattccaatt atacccataa ctatgttgcc ttttcctgtt tcagataatg tcttagagaa
    11581 tcttgatttt ctaatgaatg tagctaaacc atatcctagt ggagggataa ctattgcgca
    11641 gtttaccaat attgctggta gatagatgcc ctctaacaat aatgcatttc ctgccatcca
    11701 agctgcttta tttaccggtc ctcctaaatc aaatcctatc attgaaccta aaattaaagc
    11761 caataccacc gaatttgttc cattttgaca catttcagct acccaagcat ttaatgaagt
    11821 atttatgttt cctaaaggcc ctgctaatac aacactcatt aaaaaccccg ttaatccaac
    11881 tgttataagt ggcattatta taagtggcat cattcctgct gccgacccag atattttaat
    11941 ttttttcttt aaaaatttgc aaatatatcc agcaaaaaaa cctgctgtta ctgctcctaa
    12001 gaatcctgca ttagtattac ttgctatgag tccaccaata aaacctgcac ccatagatgg
    12061 tttttcacct attgaaaatg ctataaatcc tgctaataca gtatttaata gacctatgcc
    12121 agtccaacca acttgttcca ttaagtaaag aatatgataa aaaccggata catttttgta
    12181 agcatctaaa cttgttatac ccattgctaa agctgtaagt tttggtatag ctacaactag
    12241 agatgagcct attacaagtg gcaacatata tgaaatacct gtcattaagt gtcctttaag
    12301 ttcacttaaa agagagttat tttttttact catttttaat cctcctatat aagtttgtta
    12361 tattttttga taatatgtta taattacatt agataatttt ttaatttttg atttttctca
    12421 ttctagatta gagtgagatt ctttttatta agaaatagtt tctatacact ttgttaagac
    12481 agcttctggt ttttttaatg ctacacctat tttaactttt attacttttt taccatcaaa
    12541 tctttccatt ccagatatag tttggtcaga tgctataagt ataaagtctg catcttgtgc
    12601 ttcttctttt gttatagtat ttactcgtcc catagcacct tgttgttcta ctttgatttt
    12661 atgccccatt tttgatgcag cttgttccaa agcttttgct gccataggtg tgtgtgccaa
    12721 tcctgctata catgatgtta ttgctactat tttcataatt attcctcctt cattttatta
    12781 gttatatatt ttactaaatg acttgcatca ctagcatttt taacttcact tataaaatca
    12841 tcttccatta agcatgtggc taatttagat agagttttca aatgtatatt tccttcattt
    12901 tcatgtggag ctaacaaact aaatacatat ctaaccttac tatcatctaa agttttccac
    12961 tctaactcgt tagttgtttt aatatagagt atagaagctt cttttacatt tgcacttttt
    13021 gtatgaggta tcgcaaatcc atctcttatt cctgttggaa attcgctttc tctttttaga
    13081 aggtctttta aaagagcatc tttattagtt gtaataccta gtatataagc actgtctgca
    13141 ataaaattta atacttcctc tttgcttttt aagtctttat ctataaatat attcttttct
    13201 tgtagtacca tatatttttt ccactccatt cgtaatgtct taacttatat ttatattgta
    13261 atcgttatcc taattaaatt aaatataact aatttccact tcgacatgga aatttatatt
    13321 atgataataa ctaatttcca tgtcgaagtg gaaataaatt atgataatac aattttatta
    13381 gagtaattgt attatatgag tgtaaatagt ataatttaga agaaattcta taagggggga
    13441 tatttatgca caagagattg ctcacgttat ttaaactatt aaatgaaagt gatgataaaa
    13501 ttacttgtaa aactttaagt aatcatttaa aagtgagtga gagaactata agaaatgata
    13561 ttacttctat aaatgaaact ttagagaaaa atggtgctat tattaaaata aaaaaaggag
    13621 aaggatatta tatagatatt cttaatttag cattatacca acattatcta gcattaatat
    13681 ctgatgatat tatggattca agtgaaatac cagattctcc tatagaaaga aatcaatata
    13741 ttttaaaata tattctttat aacaatacat atataaaact agaagattta gctaatagct
    13801 tgtatgtgag taaatttaca atactaaatg atataaaaag aataaagcct attttgtcaa
    13861 agtataattt aatattagtt tctaagccat attatggagt taaggttgaa gggaaggaaa
    13921 tagatattcg aagatgtatt tctaataata tgataaatag gaattttgaa aattatataa
    13981 ttggaattac agatagagaa atagaattat ttaataatgt agatttaata gagcttcaga
    14041 agatagtgct aagtgaaatt aataaattta atatcaattt cttagatttt aatctaaaaa
    14101 attttattat tcatttatct attactataa gcagaatact aggtggttac tgcttagata
    14161 atgttttaga tgtggtttta acagattttc aatcgaatac ggctgttgaa aatatattta
    14221 attatattga gagtaaatat actataatta tttcaaaggc agacagagtt tatttatata
    14281 atcattttat aactaaaagt tctcttttgg ataacgtttc caatagggca gataccaaaa
    14341 ttatagagta tgttgaggaa attttagaag taatcaacaa tcaatatact tttgacctta
    14401 gaaatgatag tgtattattt gatgatttag tactgcactt taaatcaatt cttaattcta
    14461 aatcttataa tttaaataag gtgaatcccc ttataaatac aataaaaagt aattatcctt
    14521 tagcatttga aataagttta aatgctatag aaaaagtttt taaaaatagt atttactctt
    14581 taacagaaga tgaaattgga tatgtatccc tacatatagg tgctggaata gagagatttt
    14641 ttcaaaacaa tattaagtgt aaaaacgtag tattagtatg tggttcaggg tatggttcaa
    14701 gtaggttatt agaggttcaa ttaaacaaag tttttcatga taaaataaat atacttcaat
    14761 gtctatcatt taatcaattt ttagctagtg aattgtcaga tgtagatata ataatatcga
    14821 caattccttt aaatcatgat agtattccta ttgtattagt agatttaaaa ctattaaaaa
    14881 aagatataga gaatatatct aagtcaatca ctaataattc tcgtatttat agtaatcttt
    14941 tggacaattt ctttgataaa aatttattta ttgttaatcc taaaatcaaa gagaaggatg
    15001 agcttataaa gttgatgtgc aacaaattaa ctcaaagtga aattgtaatt ccatcattta
    15061 ctgaatctgt attctacaga gaaagtttat cttctaccaa tatagatgat tttttagcta
    15121 tacctcatcc tatggaatta agctctataa aaactaagat ttgtatttcc atattgaatg
    15181 aaccaatata ttggagtgaa gattctactg ttaaattaat catgatgttg gctataaata
    15241 aagatgatta tataaaaata aactccattt atgatatcct tttaaagata attcatgaca
    15301 atgatattag agatagtata tctaattgta atgattttga tagttttctt tccataatca
    15361 agtctataat ataaaatttt atattacata agttttataa aaaataaata gaacaatttt
    15421 ttgttgataa tataaatagt aatgagtaat ttttatatta ttttctatta ctttatactg
    15481 attgtaatta gatacaatag agggtctgtc tcaaaataga gataatcctt tttttattgt
    15541 tgaaatgata aaaacatatt tgatttcata taaaaaagag tgtctcatga actaaaaagt
    15601 tcattttgag a
//
LOCUS       DAMKOJ010000250        12684 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.097, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000250 DAMKOJ010000000
VERSION     DAMKOJ010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.097"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            8..1558
                     /locus_tag="PC592_003855"
     CDS             8..1558
                     /locus_tag="PC592_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015926181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4057733.1"
                     /translation="MFPHFSITSIFLKKTRVVAYCRVSTGSDEQLVSLQAQKAHYESY
                     IKANPEWEYAGLYYDEGISGTKKENRSDLLRMLSDCETGRIDLIITKSISRFARNTTD
                     CLEMVRKLIDLGVHIYFEKENINTSSMESELMLSILSGLAESESISISENTKWAIQRR
                     FQNGTFKISYPPYGYQNIDGQMIINPKQAEIVKYIFAEVLSGKGTQKVANDLNQKGIP
                     SKRGGRWTATTIRGILTNEKYTGDVILQKTYTDSHFNRHTNYGEKNMYLVENHHEAII
                     SPEDFEAVDAILNQRAKEKGIEKRNSKYLNRYSFSSKIICSECGSTFKRRIHSSGTRK
                     YIAWCCSKHISNITECSMQFIRDEDIKTAFVTMMNKLIFGQKFILRPLFHGLRNQNNA
                     ASFRRIEELETKIENNMEQSQVLTGLMAKGYLEPALFNKEKNALEAERERLLAEKDQL
                     TRSVNGNFAKVDEVDRLLKFATKSKMLTAYEDELFEDYVERIIVFSREEVGFELKCGI
                     TLKERLVN"
     gene            1559..1972
                     /locus_tag="PC592_003856"
     CDS             1559..1972
                     /locus_tag="PC592_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4057734.1"
                     /translation="MGHTPYGYRIEDGKAVVDEKTSEQVKELFSGYLAGLSLKEAAKK
                     AGIDCYHATAGKMLQNKHYLGDEFYPPIIDEETFEKAREEKRKRAEKLGRIREPKDEP
                     KTDYPVKFKAKPLVQKYEDPYKQAEYAYSLIESEV"
     gene            1976..3547
                     /locus_tag="PC592_003857"
     CDS             1976..3547
                     /locus_tag="PC592_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF4057735.1"
                     /translation="MAVSRNVTVIPAIKRVGNNKTSESKPKIRVAAYCRVSTDSEEQA
                     SSYEIQIEHYTNYIKKNKEWELAGIFADDGITGTNTKKREEFNRMIEECMAGKIDMII
                     TKSISRFARNTLDCLKYIRQLKDKNIAVFFEKENINTMDSKGEIMLTIMASLAQQESQ
                     SLSQNVKLGIQYRYQQGEVQVNHKRFLGYTKDENKQLVIDPEGAEVVKRIYREYLEGA
                     SLLQISRGLEADGILTAAGKAKWRPETLKKILQNEKYIGDALLQKTYTVDFLSKKRVK
                     NNGIVPQYYVENSHEPIIPRELFMQVQEEMVRRANLRGRKGGKKRVYSSKYALSSIVY
                     CGHCGDIYRRVHWNNRGYKSIVWRCVSRLEEKGSECTAPTINEETLQTAVVKAINELL
                     ANKEPFLSTLQKNIATVFNEENDNATDDIEGKLEELQQQLLIQAKSKNDYEDVADEIY
                     RLRELKQNALAENAEREGKRQRIAEMTDFLNEQSCELEEYDEQLVRRLIEKVTVFDDK
                     LTVEFKSGVEIDIEI"
     gene            3902..4771
                     /locus_tag="PC592_003858"
     CDS             3902..4771
                     /locus_tag="PC592_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF4057736.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            4752..5486
                     /locus_tag="PC592_003859"
     CDS             4752..5486
                     /locus_tag="PC592_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF4057737.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            5519..6427
                     /locus_tag="PC592_003860"
     CDS             5519..6427
                     /locus_tag="PC592_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HDF4057738.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPAEEKGYSYIILFDDYNKIDLT
                     LLPLEELGNYLNDDKLIKIILDKDGRIQQAVVPTDMDYHIRKPSAREYDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            6424..6966
                     /gene="sat4"
                     /locus_tag="PC592_003861"
     CDS             6424..6966
                     /gene="sat4"
                     /locus_tag="PC592_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HDF4057739.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            7059..7853
                     /locus_tag="PC592_003862"
                     /note="aph(3')-IIIa"
     CDS             7059..7853
                     /locus_tag="PC592_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HDF4057740.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            8129..8701
                     /locus_tag="PC592_003863"
     CDS             8129..8701
                     /locus_tag="PC592_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDF4057741.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            8674..9081
                     /locus_tag="PC592_003864"
     CDS             8674..9081
                     /locus_tag="PC592_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF4057742.1"
                     /translation="MVLNRFCRLRNEYRNFRVDRIKSICIEEELCQSHDGSLEQILKQ
                     MLSYKKLYNVILRAEKGETYNSIKNRYSLGFLEETDLGSKMEIEFQTDSFEILSKQLI
                     EYGSGIEIVQPDELKCITRKHLAQITNHCLNLI"
     gene            9192..9851
                     /locus_tag="PC592_003865"
     CDS             9192..9851
                     /locus_tag="PC592_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RibD family protein"
                     /protein_id="HDF4057743.1"
                     /translation="MKPKIIMHTQISLDGRIKGFDNPEVYYQVAGGIHSDAVLFGSNT
                     VFTAFEKYPAETEADFEKIITSPEDPRPIGVIPDSRGILRSLHCLRNLGYLKEIVILV
                     STATPKEYLNYLEERHYPYIVSGNDHVDYEKAFQILHEQYGCKYMRTDSGGGLTNKLL
                     ENGLIDEISLVISPCFVGNKEKQLFDNLLLSEKVNLELQGTENAEHGCLSLRYAVKNK
                     D"
     gene            10513..10764
                     /locus_tag="PC592_003866"
     CDS             10513..10764
                     /locus_tag="PC592_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057744.1"
                     /translation="MIHVVKIPVKNKTKEVVRITVYCRVSKNIEEQRSGLNSQIAYFK
                     ELSNKVIEIDLAEVYHDVGRSGLIKNGRTSYKKMIVDGL"
     gene            10883..11254
                     /locus_tag="PC592_003867"
     CDS             10883..11254
                     /locus_tag="PC592_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008818840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF4057745.1"
                     /translation="MSCHSIGHGLNSVSKKVLELYDEGKIEFSVAKDLLYTTRNAVHY
                     CDGNTYEAIACFDGCRCARCLKKTNELYGLYDALDECREYYDIFSNKEDGVLSGDLCK
                     DCFDEICEKHHSIIIEDEVVY"
     gene            11573..11973
                     /locus_tag="PC592_003868"
                     /pseudo
     CDS             11573..11973
                     /locus_tag="PC592_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566808.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4420 a         1901 c         2789 g         3574 t
ORIGIN      
        1 ctgtataatg tttccacatt tcagcataac gtccattttt ttaaaaaaaa cacgagtagt
       61 tgcctactgt cgagtttcta caggcagtga tgaacaactt gtcagcttgc aagcacaaaa
      121 ggcccattat gagagctata taaaggctaa tccagaatgg gaatacgcag gcttatatta
      181 tgacgagggt atcagcggca cgaaaaagga aaaccgctct gacctactta gaatgttatc
      241 agactgtgaa actgggagaa ttgacttaat tattacaaag tcaattagcc gatttgccag
      301 aaatactaca gattgcttgg agatggttcg aaaactgatc gaccttgggg ttcatatcta
      361 ttttgagaag gaaaacatca atacgagttc aatggagagc gaattgatgc tctccatttt
      421 aagtgggctt gcagaaagtg agtcaatttc catttccgaa aatacgaagt gggccattca
      481 aagacgattc caaaacggaa cctttaaaat ttcctaccca ccatatgggt atcaaaacat
      541 tgacggtcag atgataataa accccaagca agctgaaatt gtgaagtata tttttgcaga
      601 ggtattatcg ggcaaaggca cacagaaagt tgcaaatgat cttaatcaaa agggtatccc
      661 ttcaaaaaga ggtggtcgtt ggacagctac tacgattaga gggattctga ccaatgaaaa
      721 atatactggc gatgttattt tgcaaaagac ttatactgat agccatttta acaggcacac
      781 caattatggt gaaaaaaata tgtatctagt agaaaaccac catgaggcaa ttatcagccc
      841 tgaagatttt gaagctgtag atgccattct caatcagaga gccaaggaaa aaggaatcga
      901 aaaacgcaac agtaaatatc taaaccgata ttccttttct agcaaaatta tctgctcgga
      961 atgtggcagt acctttaaaa gacggattca ttcatctggt acaagaaaat acattgcttg
     1021 gtgctgcagt aagcatatca gcaatataac ggaatgttcc atgcagttca ttcgagatga
     1081 agatataaag actgcatttg ttacgatgat gaataaactc atattcggtc agaagtttat
     1141 attaagacca ctttttcatg ggttacgtaa ccaaaacaat gcagcgagtt ttcgtagaat
     1201 tgaagagttg gaaactaaaa ttgaaaacaa catggagcag agccaagtac tgacaggttt
     1261 aatggccaaa gggtatctgg aacctgctct gtttaataaa gaaaagaatg cactggaggc
     1321 agaaagagaa aggcttcttg ccgaaaagga tcaacttact cgttccgtca atggcaattt
     1381 tgctaaagta gatgaagttg accgtctgct taagtttgcc actaagtcca aaatgctcac
     1441 agcttatgag gatgagttgt ttgaagatta cgtagagagg attattgtct tttcacggga
     1501 ggaagtaggt tttgaattaa aatgtggaat cacattgaag gaaaggttgg tgaattagat
     1561 gggtcacaca ccctatggat atagaattga agatggaaaa gctgttgtgg atgaaaagac
     1621 ttctgagcag gtaaaagaat tattttccgg atacttggca ggcctttctt tgaaggaagc
     1681 tgctaaaaaa gctgggatag attgttatca tgccacagca ggtaagatgt tgcagaacaa
     1741 gcactaccta ggcgatgaat tttaccctcc cattattgat gaggagacat ttgaaaaagc
     1801 cagagaagaa aaacgaaaac gagcagaaaa gctcgggagg ataagggaac ctaaagatga
     1861 accgaaaacg gattaccctg taaagttcaa agcaaaacct ctggtgcaaa aatatgaaga
     1921 cccatacaag caggcggaat atgcctacag tttgatagaa agtgaggtgt aacaagtggc
     1981 agtgagtaga aatgtcacag tgattccggc aattaaacga gtcggaaata ataaaactag
     2041 tgagagcaaa cccaaaatac gagtggctgc ttactgtcgt gtttcaacgg atagtgagga
     2101 gcaggcttca agttatgaaa ttcagattga acattataca aactatatta agaaaaacaa
     2161 ggaatgggaa ttggcaggga tttttgcgga tgatggtatc acaggtacaa ataccaaaaa
     2221 gcgtgaagag ttcaaccgca tgattgagga atgtatggca ggaaaaatag acatgatcat
     2281 tacaaaatcc atcagccgat ttgccagaaa cacgttagac tgccttaaat acatccgtca
     2341 gttaaaagat aaaaacatcg ctgtattctt tgaaaaagaa aatatcaaca ccatggattc
     2401 caagggtgaa attatgctga ctattatggc ttcccttgcc caacaggaaa gccaatcctt
     2461 aagtcagaac gttaagctgg gcattcagta tcgatatcaa caaggtgaag tccaggtcaa
     2521 ccataagcgt ttccttggat acaccaagga tgaaaacaag caactagtca tcgaccccga
     2581 gggtgcagag gttgttaaac ggatttatag agagtacctt gaaggagcta gtcttttaca
     2641 aatatcaaga ggactagaag cagacggtat tcttacagcg gcaggcaaag ccaaatggag
     2701 accagaaaca ctaaaaaaga tattgcagaa tgaaaagtac atcggtgatg cccttctaca
     2761 aaagacatat acggttgatt tcctttctaa aaagcgggtc aagaataacg gcatcgttcc
     2821 ccagtattat gtagaaaaca gccatgagcc gattattcca agggagcttt ttatgcaagt
     2881 tcaagaagag atggttcgaa gagcaaatct tcgtggccgc aaaggcggta aaaagcgagt
     2941 ctatagcagc aagtatgctt tatcgagtat tgtttactgc ggacactgcg gcgatattta
     3001 ccgacgggta cattggaata acagaggcta caagtctatt gtttggagat gtgttagccg
     3061 attggaggaa aaagggtctg aatgcactgc tcctaccata aacgaggaaa cattgcagac
     3121 agcagtggtc aaggctatta acgagctttt ggctaacaaa gaacccttcc tctcaacctt
     3181 gcagaaaaac atagctactg tatttaatga agaaaatgat aatgccaccg atgatattga
     3241 aggcaaattg gaagaattac aacaacagct tcttatacaa gcaaagtcca agaatgacta
     3301 tgaagatgtg gctgatgaaa tttaccgcct tcgagaattg aagcaaaatg cacttgcaga
     3361 gaatgcagag cgtgaaggaa aaaggcaacg aatcgctgaa atgactgatt tcttaaatga
     3421 acaatcctgc gagttggagg aatatgatga gcaattagta aggcggctta ttgaaaaagt
     3481 tacggtattt gatgataagc tcactgttga atttaaatca ggtgttgaaa tagatattga
     3541 gatataggat atcagaaatg gcgaccaatt gagaggtgtt acttccttga ttggtggctt
     3601 ttcttattta cggattgact ttgactgtga atatacgtat aataatatca acaatgttgt
     3661 tgatattatt attaataagg agtggacaac atgattgatg taaatgagct attttagcaa
     3721 aatgaatggt aatttaaagg ctattgaaaa gacttcatct aatcagcaga ggtataaaaa
     3781 gacaattgat aagttttaac tatcttttgt gaaattaaaa aaattataaa tatgttgagt
     3841 agaagcaaaa gatttggctt ggaattttta cagcagtgaa tcgataaaag gagcatgctt
     3901 gatggtagat aatattatta aatcagtagc agagaaatta tcctctctgt cttatataga
     3961 aggtattgtt ttaggtggtt cacgtgcaag gggcacccat acagaggatt cggatataga
     4021 tatcggcatc tattacaatt cagaatcatt tgacataaat actattaatc aattcgctac
     4081 aaagctggat gatgagcata gaaataacct tgttgtacct cccggagcat ggggtgattg
     4141 gattaatggc ggcggatggt tagtcataaa cgggtatcat gtggatttaa ttttacgtga
     4201 tattaaacgt gtggaacaaa taatgaaaga tacagagcac ggaattgtta ctgccaatta
     4261 tcagactggg catccccatg gttatattag tgcaatgtat cgaggagaat tagcgattag
     4321 caaaatacta tatgctaaga atgaaagctt atgcgaatta aaaaaacagg cagaaactta
     4381 tcccaatgct ttgcagaaaa gtttagttaa cttttttatg tttgaagcag ggttctcttt
     4441 aatgtttgta aaagcaaatt cgggaacaga cgataaatat tatattgcgg gtcatgtttt
     4501 tcgtatagtt tcatgtttaa atcaagtgtt atttgcatgt aataatgctt attgtatcaa
     4561 cgaaaagaaa gctataaaac tgcttgaaac ttttgaacat aaacctgaaa aatataccga
     4621 gaaggtaaat catatttttg aagtactcgg tatctcactt tttgaatgct acgacatgac
     4681 cgagaagctt tataatgaag tgaatgaaat tgtatcggag ataaataact ttttaaacga
     4741 ggagagttca gatgaaagaa aacaaatatg atgataatat attttttcaa aaatacagtc
     4801 aaatgagtcg ctcgcagaaa ggactggctg gtgcgggaga atgggagact ttgaaaaaga
     4861 tgctacctga ttttaagggt aagcgtgtgc ttgatttagg atgcggctat ggatggcact
     4921 gtatatatgc gatggaaaac ggtgcttcct ctgtagtagg tgttgatatt tctcataaaa
     4981 tgctcgaagt agcaaaagga aaaacccatt ttccacagat tgaatatgaa tgctgtgcca
     5041 tagaagatgt ggatttccca gaggagagct ttgatgtaat actaagttcg cttgcgtttc
     5101 attatgtagc agactatgag aatttaataa aaaagatata taggatgctg aaggctggtg
     5161 gcaatttagt ttttacagtt gaacatcctg tttttactgc tcatggaaca caagactggt
     5221 attataacga aaaaggagaa atactgcatt tcccggtgga caattattat tatgagggca
     5281 aacggacagc tatgtttttg gaagaaaagg ttacaaaata tcatagaaca ctgaccacat
     5341 atctaaatac actgctttca aatagtttta taataaatca gattgtggag ccacagccgc
     5401 cagagaacat gatggatatt ccggggatgg cggatgaaat gcgacgccca atgatgctga
     5461 ttgtatcggc aaaaaagaag atgtaataat atagaaaaaa taaacgagga gtatgtaaat
     5521 gagatcagaa aaagaaatga tggatttagt actttcttta gcagaacagg atgaacgtat
     5581 tcgaattgtg acccttgagg ggtcacgcgc aaatattaat atacctaaag atgaatttca
     5641 ggattatgat attacatatt ttgtaagtga tatagaaccg tttatatcta atgatgactg
     5701 gcttaatcaa tttgggaata ttataatgat gcaaaaaccg gaggatatgg aactattccc
     5761 ggctgaagag aaaggctact cctatataat actttttgat gattataata aaatagacct
     5821 taccttattg cccctggaag agttgggaaa ctacctgaat gacgataaat tgataaagat
     5881 tattctggat aaggatggaa ggattcagca agctgtagtt ccgaccgaca tggattatca
     5941 tataagaaaa cccagtgccc gggaatacga tgactgctgc aatgaattct ggaacaccac
     6001 tacctatgtg gttaagggac tgtgccgtaa ggaaatttta tttgctattg atcattttaa
     6061 tcagattgtt cgccatgagc tgctgagaat gatatcatgg aaggtcggca tcgaaacagg
     6121 ctttaaatta agtgtaggca agaactataa gtttattgaa aggtatatat ccgaggattt
     6181 gtgggagaaa cttttgtcca cctaccggat ggattcctat gaaaacatat gggaagcatt
     6241 atttctatgc catcaattgt tcagggcggt atccggtgag gtggcggaaa ggcttcatta
     6301 tgcctatccg gagtatgata ggaatataac aaaatatacc agggacatgt ataaaaaata
     6361 cactggtaaa accggctgcc tggatagcac atatgccgct gatatagaag agaggcggga
     6421 acagtgatta cagaaatgaa agcagggcac ctgaaagata tcgataaacc cagcgaacca
     6481 tttgaggtga taggtaagat tataccgagg tatgaaaacg agaattggac ctttacagaa
     6541 ttactctatg aagcgccata tttaaaaagc taccaagacg aagaggatga agaggatgag
     6601 gaggcagatt gccttgaata tattgacaat actgataaga taatatatct ttactaccaa
     6661 gacgataaat gcgtcggaaa agttaaactg cgaaaaaatt ggaaccggta cgcttatata
     6721 gaagatatcg ccgtatgtaa ggatttcagg gggcaaggca taggcagcgc gcttatcaat
     6781 atatctatag aatgggcaaa gcataaaaac ttgcatggac taatgcttga aacccaggac
     6841 aataacctta tagcttgtaa attctatcat aattgtggtt tcaaaatcgg ctccgtcgat
     6901 actatgttat acgccaactt tgaaaacaac tttgaaaaag ctgttttctg gtatttaagg
     6961 ttttagaatg caaggaacag tgaattggag ttcgtcttgt tataattagc ttcttggggt
     7021 atctttaaat actgtagaaa agaggaagga aataataaat ggctaaaatg agaatatcac
     7081 cggaattgaa aaaactgatc gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc
     7141 ctgctaaggt atataagctg gtgggagaaa atgaaaacct atatttaaaa atgacggaca
     7201 gccggtataa agggaccacc tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg
     7261 aaggaaagct gcctgttcca aaggtcctgc actttgaacg gcatgatggc tggagcaatc
     7321 tgctcatgag tgaggccgat ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc
     7381 ctgaaaagat tatcgagctg tatgcggagt gcatcaggct ctttcactcc atcgacatat
     7441 cggattgtcc ctatacgaat agcttagaca gccgcttagc cgaattggat tacttactga
     7501 ataacgatct ggccgatgtg gattgcgaaa actgggaaga agacactcca tttaaagatc
     7561 cgcgcgagct gtatgatttt ttaaagacgg aaaagcccga agaggaactt gtcttttccc
     7621 acggcgacct gggagacagc aacatctttg tgaaagatgg caaagtaagt ggctttattg
     7681 atcttgggag aagcggcagg gcggacaagt ggtatgacat tgccttctgc gtccggtcga
     7741 tcagggagga tatcggggaa gaacagtatg tcgagctatt ttttgactta ctggggatca
     7801 agcctgattg ggagaaaata aaatattata ttttactgga tgaattgttt tagtacctag
     7861 atttagatgt ctaaaaagct ttaactacaa gctttttaga catctaatct tttctgaagt
     7921 acatccgcaa ctgtccatac tctgatgttt tatatctttt ctaaaagttc gctagataga
     7981 gttctatatt agagatgtaa agagttttgg tgaagaggtt tgtgagtatg gcttttataa
     8041 ccagggtgca atgagaagca ctaacagcag ctagcttaag aacgcatagg atatactttt
     8101 tatggaagtc acagaggagg aataaaattt gaacaggatt aacagagtaa cctctattct
     8161 tattcagctg caatcaaaaa aaataattcc tgccaaagaa attgcacagc gatttaatat
     8221 aagcttaagg acagtttaca gagatatccg gacacttgaa gaagccggaa taccaattgg
     8281 atctgaggcc ggaaaaggat attttcttgt agagggcttc ctacttccgc cggtaatgtt
     8341 tacagcggcg gaagtgggtg cattgattac agcagggaaa tttttaaatt gccatggaga
     8401 tgaatcattt ataaaggatt ttgattcagc tatgtataaa atcaaatcta ttttgaagca
     8461 tggtgaaaaa aactatgcac aggagttgga gaacagtatt aacgtgtaca gcacatctgg
     8521 acagaaaaat acattggcgg ataacgttat tgcagcaatt cagactgcaa tctgcaataa
     8581 aagggtaata tcaattcaat atcctgcatc aggagggcaa gaaccggaaa gcagaatgat
     8641 agagcctata tcactggggt tttatgaaca gaactggtac ttaatcggtt ttgcaggcta
     8701 agaaatgaat ataggaattt tcgtgtggat cggattaaaa gcatttgcat agaagaagag
     8761 ctctgtcaaa gccatgatgg ctctttggaa caaatattaa aacaaatgct ttcatataaa
     8821 aaactatata atgtaattct tagagctgaa aaaggggaga catacaattc tatcaagaac
     8881 aggtattctc tcggcttcct tgaagaaacc gatttgggaa gtaaaatgga aatcgaattc
     8941 cagacagatt cctttgagat attgagcaag cagctgattg aatatggatc aggcattgaa
     9001 atagtccaac ctgatgaatt aaaatgcata acccgtaaac acctggcaca aattacgaat
     9061 cactgcctaa acttgattta gagaaagcga ttggtctgtt atgtattttt tgtaaggttt
     9121 catatcccct gctgacatac agctgtcagt gtattatgat attctactat caaaaaggag
     9181 gattgaaaaa tatgaaacca aagataatta tgcacacaca aattagcctt gatggccgca
     9241 ttaaaggctt tgataatccg gaagtttact accaggttgc cgggggaatt cattcggatg
     9301 cggtgctgtt tgggtccaat actgttttta ctgcatttga aaaatatcct gctgaaacag
     9361 aggctgattt tgagaaaatc ataacaagcc cggaggaccc cagaccaata ggagtcatac
     9421 ctgacagcag aggtatcttg agaagtcttc attgcttaag aaatcttgga tatctgaagg
     9481 aaattgtcat tctggtatca actgccactc cgaaggaata tttgaattat ttggaggaaa
     9541 ggcattaccc atatattgtg tcaggaaatg atcatgtgga ctatgaaaaa gcctttcaga
     9601 tcctgcatga gcaatatggg tgtaaataca tgcggacaga cagtggcggt ggattaacca
     9661 acaaattatt agaaaacgga cttattgatg aaatcagtct tgtgatatca ccatgttttg
     9721 taggtaataa agaaaaacaa ctatttgata accttctgtt atctgaaaaa gttaatttgg
     9781 aattgcaggg aacagagaat gcagaacatg gctgtctgtc attgcgctat gctgtgaaaa
     9841 ataaggatta gtgcagcata ctttaaaaag tgtctgttgg gacagtgtcc taaaggaagc
     9901 ataagctcat ggctagcggc ggtgttaaag taacggcact cggccccaat atatagttga
     9961 tatgccccta agcctttgag ggcaaggcgg tcaaccgcgc cttttccggt ccgcatacag
    10021 tcgttcaatg agggtatcaa gctcggcaat gcggcggtgc ttctcggtgg ttcgtttctt
    10081 cgccgccgtt ttcggctaat tctaattgat ccgaactgta aggataagca attatccggg
    10141 gctagttaag tatcttagag aggaagataa agataagtaa accaatttta aagttgtacc
    10201 gaataaagcc ttcaagagga caacatgctt ttgaaggctt tattgcttac aattacttgg
    10261 attgtaacgc aaaagcaggc accaaatcaa tgaaaaatag cctatccagg cgactgtttc
    10321 agaaatatgg gcttccgcca aggggatacc agtggggtgc gacatctttt ttgcccactc
    10381 aaggcatgta gagtccattg ttctgttgcg aaaaagataa aaaatcaaat cagttttata
    10441 gagatgtaag ttgttgatga taacttgcat ctttttcata tgttaagatt ggagtgataa
    10501 ggatgataaa aaatgataca tgtagtgaag ataccagtta aaaataaaac gaaagaagta
    10561 gtaagaatta cagtatattg tagagtaagt aaaaatatag aagaacaacg ttcaggttta
    10621 aatagtcaaa ttgcatattt taaagaactt tctaacaaag taatagaaat cgatttagct
    10681 gaagtgtatc acgatgttgg aagaagtggg ttaataaaga atggaagaac aagctataaa
    10741 aaaatgattg tagatggatt ataaggcaaa tttgattaca ttattacaaa atcagttagt
    10801 aggtttataa taaagcattg tagtaaaata aaaaaatatg atatatttag attagtgata
    10861 ataaaaaaaa ggagctaaaa atatgagttg tcatagtatt gggcatggat taaattcagt
    10921 gtctaaaaag gtattagagt tgtatgatga agggaaaatt gaatttagtg ttgcgaaaga
    10981 tttattatac accacaagaa atgctgtaca ttattgtgat ggaaatacgt atgaagcgat
    11041 tgcatgtttt gatggatgta gatgtgctag atgtttaaag aaaacaaatg agttatatgg
    11101 tctttatgat gcattagatg agtgtagaga gtattatgat atttttagca ataaagaaga
    11161 tggagtatta tctggtgatc tttgtaagga ttgttttgat gaaatttgtg aaaaacacca
    11221 ttcgattatc atagaagacg aagttgtata ttaaaaaagt tttactcgat aatgggtaaa
    11281 tcttcaactt ttagcggaat tattagcaga tagtaataat atacctatga tatttgtgaa
    11341 gtttaatctt atattttcaa taagggatta ctatacacat tgcttatctc ttttaatctt
    11401 tgattcacgt tgagagtgtt gtcttgatgt caagggttca gaagtaacat gtgaaaaagg
    11461 cttgaaaata ggtcatttta aaaatagatt gtaattttta agtacattga aatcacgaaa
    11521 atgcttgtaa atcagggcat ggaaacatat caatacggac agtggagttg acagagtagt
    11581 aaccaaaatt gaaggtgtga actggtcttt tagcgataaa atgtttgtct actttataaa
    11641 tgatttagag atgtatagta agtgggaata ttcaggtgaa agtgagttgc ttatgttgga
    11701 atataaagag ggcatactat cttttgataa tataatgcaa ttctatttag ataaaatgat
    11761 gcgggataag gttattgatt caattccttc attttttcag cagttactta gaatctgtaa
    11821 aaagtttaaa gcattaaaag acattagtaa cgcatttgga agggataaat taatccaagt
    11881 aactaaagaa aatattttaa taatattcca tcaagtctgg caaaggtatt tatacaggga
    11941 aaatatttct gtattcaaaa ctatggaaaa tgagctgtat acaattttca aaggaatgaa
    12001 atggaacagt tttatgaata aaataaaagt attcgttcag aagccggaag taaaatatat
    12061 caatctgtaa cctttgcaat ggtggaagca tattggaata aggataaaag tattatagat
    12121 aagcagggtt gagaggaaga gtctgagtat ggaccagatt aatagttgaa ctatctaaac
    12181 ataaattggc agatttcgga atagaattta ctattgtaaa tctttaaaat atgcgtcagt
    12241 tttatcttgc ttttccaaaa actacgtatt gtgtcgcgaa ttgagttgga cacattatcg
    12301 cttgcctatg cgagtggaga aaccccgtga attttaacga ataaatttac tccaccatta
    12361 tgtaatgaaa atacttttgt catggtgtat aaggccttta ttttactgta tgtggagtca
    12421 tagcattgct atgtagagtt gaaaagcctg ataaacaaag gctttctttt atttatgtct
    12481 actcaaaaat actgctttca tttgtatttt aataaaaaat tatgttatgc tcgatatgga
    12541 ataaaaaaca catttaaaat ggaataggag aatgtcaaga tgaagattaa tataagtacc
    12601 attatagagg cgattgaaat ggcagatgat aattttacat tttttttatc tgataaaaat
    12661 aatatttctt ttaatttttt catt
//
LOCUS       DAMKOJ010000251        11087 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.105, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000251 DAMKOJ010000000
VERSION     DAMKOJ010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11087
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.105"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            125..1531
                     /locus_tag="PC592_003869"
     CDS             125..1531
                     /locus_tag="PC592_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF4057746.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYNNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGIDFYNKII
                     DKLIECDIEPFVTLYHFDLPFTLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMRYLEKRNIVPHM
                     EDGDKEVLKKAKMDFIAVNYYRTNCAGAFPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACRLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            1559..2407
                     /locus_tag="PC592_003870"
     CDS             1559..2407
                     /locus_tag="PC592_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF4057747.1"
                     /translation="MYITKVLNNSLLLARDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLELPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSKEKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            3067..3759
                     /locus_tag="PC592_003871"
     CDS             3067..3759
                     /locus_tag="PC592_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF4057748.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEHIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKNDNYSKVHGLRAGADDYLTKP
                     FEIAEFTARVLSLIRRYTRFNPKNEESQQLSFKGLLIDLDQHTVTTNGETMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            3756..4691
                     /locus_tag="PC592_003872"
     CDS             3756..4691
                     /locus_tag="PC592_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF4057749.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYIEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLDFEIDIPENRLMVNLDSDGYSRVVNNLVQN
                     VLAHSKARRIKITMSEDSKMVLLRVEDNGVGIAKENLQHIFERLYKCDKGRSKKGSGL
                     GLSIVSQMVERMGGKISVESEIGKYTVFIVSLPLI"
     gene            4841..5764
                     /locus_tag="PC592_003873"
     CDS             4841..5764
                     /locus_tag="PC592_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF4057750.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGSGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRNLCTERGKTILISSHILSEIALLADDIGIIDRGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLEIQLNLKNFKVADNHNIMLYDTDVSVAEINRAF
                     IQNNIDVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            5748..6518
                     /locus_tag="PC592_003874"
     CDS             5748..6518
                     /locus_tag="PC592_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057751.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIVFGIMFFVTALPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICIIYKKQEN"
     gene            6528..7310
                     /locus_tag="PC592_003875"
     CDS             6528..7310
                     /locus_tag="PC592_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF4057752.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQIVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFVITLIGGYLINREYTDQTLKNILTIPISLRKLLVGKL
                     IAVGGITVLLSIFSFLCTFILGLLFCNINISVILVAKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNSFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLAGYNNDDGSVYQPLI
                     GVMTLVVILILTAILLTFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            7688..8224
                     /locus_tag="PC592_003876"
     CDS             7688..8224
                     /locus_tag="PC592_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF4057753.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            8256..8645
                     /locus_tag="PC592_003877"
     CDS             8256..8645
                     /locus_tag="PC592_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF4057754.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLSQLTEHGFIKKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLKELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            8682..9068
                     /locus_tag="PC592_003878"
     CDS             8682..9068
                     /locus_tag="PC592_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF4057755.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNSVTVKVSSAIHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            9195..10637
                     /locus_tag="PC592_003879"
     CDS             9195..10637
                     /locus_tag="PC592_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF4057756.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDENIAEDIVEDEPKLNTEKDGDLNYVSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAKSKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGKDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            10934..11053
                     /locus_tag="PC592_003880"
                     /pseudo
     CDS             10934..11053
                     /locus_tag="PC592_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574155.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
BASE COUNT         4001 a         1393 c         2092 g         3601 t
ORIGIN      
        1 aaagaaaata gttaatataa agtgaactta ttgtaatgaa ttattaaaga aaataattaa
       61 tatagattaa acttatttta atgaagtaca aagaaaataa tcaatataaa aaggagaaat
      121 atttatgaat acaggatttc caaaagattt tttatgggga gcatcatctt ctgcatttca
      181 agtggaagga gcttgggata aagataataa aggaaaaacc gtagctgact ataattcttt
      241 taaaaagtct catttacagg cagatactaa agtggcatca gacttttaca ataattatga
      301 agaagatatt gaattaatga aagaattagg gatgaaaaca tatcgttttt caatttcatg
      361 ggcaagaata ataccagatg gtgaaggaga gataaaccag aaaggtatag atttttataa
      421 taagataata gacaaactaa tagagtgtga tattgaacca ttcgtaactt tataccattt
      481 tgaccttcca tttacattag tagagaaata taatggctgg gaaagtagag aaactgtcta
      541 tgcttttgaa agatttgcta aaatatgctt taagcatttt ggagatagag taaagtattg
      601 gcaacctcat aatgaacaga atttaattgt tagagtggaa gagagaatta atatatatga
      661 tgaaacagat tcatggaaaa tagataaaat gcgtgctcaa atggactata atctttgttt
      721 agcacatgca ttagcagtca atgcatgcca tgagatgata aaagaaagta aaattggagc
      781 agcagtatca tcatctgtaa catatcctct tacttccaag ccagaagatg tatatgcagc
      841 tagaatgaat gataatttta aagtgtacta tatgcttgat atgcatcact atggagaata
      901 tccagggtat tatatgaggt atcttgaaaa aagaaatata gtccctcata tggaagatgg
      961 ggataaagaa gtacttaaaa aggctaaaat ggattttata gctgtaaatt attatagaac
     1021 aaattgtgca ggagccttcc cagaggattc acaacatcca tttgggttaa gagaaggaac
     1081 tgttgatttt agtatgtatg gattatttaa aatgtcaatg aatcctaacc tagaagcttc
     1141 tgagtatgga gcagcaatag acccatcagg tcttagagtt gccttaaatg aatattggca
     1201 aagatatcac ttacctgtta taataacaga aaatggtctt ggagctaaag acatattaga
     1261 agatggaaaa attcatgatg actatcgtat agattattta aggagtcata taaatgcatg
     1321 tagactagct attgaagatg gtgtagagat gattggatat tgtccatggt catttacaga
     1381 ccttttaagc tcttctcaag gttttaataa gcgttatgga cttgtttata taaatagaac
     1441 tgaccatgaa gttttagatt tgaaaagaat caagaaagat agtttttact ggtacaaaga
     1501 agttatagag aacaatggaa tagtaaaata aacataaata tatattgagg gttttagtat
     1561 gtacattaca aaggtattaa ataattcgtt gctacttgca agggatgata atgatgaaga
     1621 aataatattg atgggaaaag ggattggcca taattataag gctgggtctg agttaaataa
     1681 aaaagatata gaaaagattt ttgttcttca tgatgaaaat ataaaaaaga gtattataca
     1741 actggcaaca gaaatagatg cagaatattt tggtatagct caaatgataa ttgcatatgg
     1801 aatagaaaaa tataacttaa aacttatgaa ccatatatat ttggccttaa ctgaccacat
     1861 tgcctttgca gtgagacgct ttaaagaagg tataatgatt gaaaatcact atttgtttga
     1921 aatcaaggag tttaatccaa aagagtatga tataggaaaa tatgcaatta ctgtttttaa
     1981 ggaggttctt ggtttagaac taccagaaga agagattggt aatatagcag gccattttat
     2041 aaatgcacaa caagataatc cttatagtga tagaaataag agaagtgcta aaattgtaaa
     2101 tgctattttg caaatagttc attatcactt ttctattgta tataataaag agtcatttta
     2161 ctataggaga tttgtaatgc atctaaaggc cttttcacaa agatttctgg ctaacgaacc
     2221 gtcaaaagaa aaaatagatt ttatatatga gcaagttcaa aaaaattgta aggaagagta
     2281 tgaatgtgtg aaaaaggtag gagcttatat gtataaggaa tactccagag aattaccaag
     2341 acaagaggag ttatatttga tgattcatat tcataagatt ttaggagaat tatgcgaaaa
     2401 tagttagaat atcttaatat gctagtaata ttataaaaaa ttaaaaatta attacacttt
     2461 aaatatgaat aattgcatta cttaaggggg ttgtcttaaa attgattttt ttaattaaat
     2521 tttaagttca actccttttt aaacctttat atcattacaa ctttaatgtt tatacgcctg
     2581 tacttcagat gtgtatctat tttttacatt tctcaacatg aaaatttatc attttttgta
     2641 gtgtgttaat tgaaataaac ctttgagtta accctaaatt tattctggac ctacaggaat
     2701 agttccaaag atactttaaa atattttctg gaatgattgc ttatttcata tatattttat
     2761 tgtgatgttt tgatttaata aattcttcaa ctccgtatat agtaaatgta ttatcatgtt
     2821 tgttttattt aagcacactt ataatatgct tgattttttc aaaatgatga aatatactaa
     2881 tgggtgttgg atgtataaga atcacattat acttgaaaaa gtaagtgaga aatgaggtat
     2941 aattcctcat atgataaact actattgtat tgtggaacat attctcagtg atgtcaagat
     3001 attacaatat gactaaattc ctaatgataa aaaagtctac gaatgagtgt agaaagggga
     3061 actaagatga ataaagtttt aattatagat gatgataaag atctttgtat tttgttaaaa
     3121 aagagtatct caattgaaca tattgaagca aactattgcc attctgggag agatggattg
     3181 gttgaacttt caaaacaaga ttatcagtta gtagttctag acgtgatgat gccaggtatg
     3241 gatggttttg aaactatgga acaaatacga aaatatagca gtattcccat cttaatgctg
     3301 acatcgaaaa atgataatta cagcaaagtt catggattgc gagctggtgc ggatgactat
     3361 ctaaccaaac catttgaaat tgcagaattt actgctcgtg tactgtcttt aatccgacgt
     3421 tacacccgtt ttaatccaaa gaatgaggag tcacagcaac tttctttcaa aggtctgttg
     3481 attgaccttg accagcatac agtgactacc aatggcgaaa ctatgttgct tccacccaag
     3541 gaatttggtg tgcttcttta ctgtgcaagg catcagggta agattttgac aaaacagcag
     3601 atttatgaag ctgtgtgggg tgagccatat gtatatgatg acagcaatat catggctatt
     3661 atcagtcgcc taagaaaaaa aattgaacta gacccatcat ctcccatcta tttgcaaacg
     3721 ataaaaggaa tcgggtatca attcaacacg gaggtatgaa aatggatgaa caaacgataa
     3781 ttcttttttt gtttttgctg tcgattggtc tacttttcct ttccatattt gctttttcca
     3841 agcttggtca tattcacaaa cgtctaaaag atatagaaga aatacttgct gatgtacaaa
     3901 ttggaaacga aaatcgaaaa atactaatta agccatgtga tgttatggct ccattggttt
     3961 atcagcttaa tgagattgtc tacgattatg aaaataagtt actttctctg aaaaagtcgg
     4021 ataaagctag caaacaactt atgacaagtt tatctcatga tgttcgtaca ccattaacga
     4081 ctctgattgg ttatctggat gctgtacaca gtggtatagt tatcggacaa gaacgggagg
     4141 aatacattga aatcgctcgg cgtagagcct acgaccttaa ggattatatc gatgttcttt
     4201 ttgactggtt tcgattgaac tctgatgaat ttacgttgtc aatagaatct gtggaaattg
     4261 cagagttgtc acgtaatatt cttaaagatt ggattcctat cttccatgaa aagaaattgg
     4321 attttgaaat tgatattcca gaaaatcgac taatggtaaa ccttgattca gatggatatt
     4381 ctcgtgtagt caataatcta gttcaaaacg ttcttgccca tagcaaggct cgccgaatca
     4441 aaattaccat gagtgaggat tctaagatgg tattacttcg tgttgaggat aatggtgttg
     4501 ggattgccaa agaaaattta cagcatattt ttgagcgact gtacaagtgt gataaaggac
     4561 gttcaaaaaa aggaagtggt cttggtttat ccattgtcag tcagatggtg gagcgaatgg
     4621 gcggtaagat ttctgtagaa agtgaaattg gaaagtatac cgtatttata gtgagcttac
     4681 cattaatata aaaattgttt ttcccccatg tgatatatat acacaggggg gattttttat
     4741 aagctataaa gttgcaaggt taatacaagg ttgttgcaag gttaatgtaa gattgaggtg
     4801 gtatgataaa tttaataaac aaaggaggat tttactattt atgaataatt taattattga
     4861 aacaaaaaat ctcactaaac aatatggtgc tcaaaagagc gtttctaatt tgaatattca
     4921 tgttcagaaa ggtcgtattt atggattgct gggaagaaat ggttcgggta agacgacaac
     4981 tatgaaaatg ttattgggtc taacaaaacc aactactgga gaaattaaaa tatttggtca
     5041 ggatattcat aataacgaga aaaagcttct tcctagaatt ggatgtttga ttgaatcacc
     5101 aggtttttat cctaatctga caggaacaga aaatctcaaa atctttgcga ggcttagagg
     5161 aataccaaaa aaaaatgcag tagaatcagc actggatgta gtcggtttgc caaacaatga
     5221 caaaaagtta ttttctcaat actctcttgg tatgaaacag aggttggcaa ttgctcttgc
     5281 cattatgcat gacccacaat tgttgatttt ggacgagcct atcaatggac ttgatcctat
     5341 tggtattgca gaagtaagaa agtttattcg taatctctgc acagaacgag gtaaaactat
     5401 tttgatttcc agtcacattc tttctgaaat tgctttgttg gcagatgaca ttggcattat
     5461 tgaccgtggc attttgttgg aggaagaaag ccttgcacaa ctggaagaaa aaaacagtaa
     5521 atacatacat tttgctgtat ctgatgcagc acaagcagca agacttctgg aaatccagct
     5581 taacctgaaa aatttcaaag tggcagacaa tcacaatatt atgctttatg atacagatgt
     5641 ctctgttgca gaaataaatc gtgctttcat tcaaaacaat attgatgtat cagaatctca
     5701 tttgtgcgaa gatactcttg aagattactt caagaaagta acagggggtg aaggaattgc
     5761 ttgatataat ttcatgcgaa ttttcaaaac tcaagcggtt aaaatttata ctgatttcta
     5821 ttttaggtgc ttgtttattt ccaattcccg caacaatttt gattgcaaag gacaacttgc
     5881 cttttgagca attgttcaaa ttagttgtca attttggata ttttttgcta ttaccaattg
     5941 tattgagtat tgttgctagc caactctttt tcatagaaag agataacgat gtattaaaaa
     6001 atctagcaac agtgccagtg ccaaaaggaa aactggctct ggcaaaatta gctgtgttgc
     6061 tgtttatatc attgttctac tccgttgcag ggttaggagc tactatcata ggaggtttca
     6121 ttgttggaat agtagagggg gttgctgtaa aattaggaat gagtattgtt tttggaatta
     6181 tgttttttgt tactgcactt cctgttgtgg tactcattgt atatttcaat cgcagctata
     6241 ttttttctat tatactttct tttgtatatg ctattttcaa ttttagtata tccttaaata
     6301 ttatcaactt tgaaccaaat aacccactgt taagcgtatt acctgctcct gttataatgc
     6361 gttggtggat ggcattttgg ggagatccca ctggcgaata cacggcactt agacagccat
     6421 atttactctc aactcctgct tgtgtaggta ttttatgttt gataacaatt attgcagtcc
     6481 tgttgatttg tataatctac aagaagcagg agaattagga ggtatctatg cttgatataa
     6541 ttactacaga atttcaaaaa ataaaaagat ataatattct atggattggt gttgttgctg
     6601 ttctgttttc agcactattg gcggtttttc agattgtaag ttcacacggc agtgaccctc
     6661 taacgtatga gagctttgca aatggagtta tatggaataa tttcagtctt agttttccat
     6721 ttgtgattac gctcattgga ggatatctta ttaaccgtga atatacagac caaaccttaa
     6781 aaaacatcct aactattcct atttcattac gcaaattgct agtgggaaaa ttaattgcgg
     6841 ttggaggaat tactgtattg ttaagtattt tcagcttctt atgcacattt attttagggt
     6901 tactattttg caatatcaat atatctgtta tactcgttgc aaaatcctta gttcagattt
     6961 tgtctgttaa tctgtattgt tatgttgctg ttttgccgat tattgcttat tttggtcgta
     7021 aacaaaattc ctttttgaca ggcgtaggga ttgcatttgt atatggcttc tgtggtgtat
     7081 ttgttgctgg aagaaatcta acagactttt atccaatcac agcaggtctt ggtctagctg
     7141 gatacaacaa tgatgatggt agtgtttatc agccacttat aggtgttatg actttggttg
     7201 taattctaat cctgacagct attctactta catttacacc taattacgat aaagttatga
     7261 ccatatctaa gaaaaaaggg ataaagcata aaaagtattc tcataaataa cataaatatt
     7321 gtttctatta tttaagttgt caggcagtga aaagaaaaaa tctgtcgtac agtggctata
     7381 tgctcatgta tttaagaagc tacagttttg atttttcata ggtgtggctt ctttttgtat
     7441 ttattaaatc aacaactatc ataatatttg caataggtat agtaacaaga gataatactg
     7501 tcatatgtgt tttatatatt acattaagta tattctaaaa tatatgtttt aaataatata
     7561 tttgaaaata agaatacttg aataaaaaaa ataatattat atatagttga caaaaagtgg
     7621 aaattaatat actatataaa tatagaaata gtaatcatta ctaatattaa aaaaggagga
     7681 attaattatg aacttaaaag gaactaaaac agaaaagaat ttaatggcag gatttgcagg
     7741 agagtcagaa gcaagaaata aatatacata ctacgcttca aaagctagaa aagaaggtta
     7801 taatcaaata gctgctatat ttgaagaaac tgctaacaat gaaaaggaac atgctaaatt
     7861 atggtttaaa cttttacatg atggtatgcc ttcaacagag gaaaatttaa aggatgcagc
     7921 agcaggcgaa aactatgagt ggactgacat gtatgcgaaa tttgctaaag aagctagaga
     7981 agaaggattt gacaagatag cttatttatt tgaggctgtt ggaaaaatag agaaagagca
     8041 tgaagaaaga tacttaaagc ttttagaaaa cttaaatgaa ggaaaaatat ttaaaagaga
     8101 tgaagaagtt gtttggcaat gtcaaaactg tggtcatgtg tatgtaggta ctgaagcacc
     8161 agaaaaatgt ccagtatgtg accatccaaa agcatatttc aatataaaag ctgaaaatta
     8221 ttaaaaatta tcattattaa aaaggaatgt taactatgaa attttctaaa caacgagaac
     8281 tgattttgaa tgaaatatta aataatccgg ttcatcctac tgcggattac ctatatgaaa
     8341 acttaaaaaa agataatcca aatctaagct taggaactgt gtatagaaat ttatctcaac
     8401 taacggaaca tggctttata aaaaaggtta gtattccagg gtatccagat agatttgatg
     8461 gtagaataga taatcactat catatcatat gtgaagtatg tggagaggta tacgatttag
     8521 aatctgaagt tcttaataat ttaaaagaat taatatctga ggagacagac ataaaaataa
     8581 catcttataa cataagtttt aaagggattt gtaataattg taaaagatgt agccaagtag
     8641 gttagctttt aaattctaaa aataattaat gaggtgagtt tatgtgtagc gaacaaaaat
     8701 tttttatatg tgagacttgt ggaaatcttg taggaatgat acaaagtggt ggtgtaccta
     8761 ttttctgttg tggaaaacct atgaaggagc ttgttcctaa tacaacagat gcagcagttg
     8821 aaaaacatgt acctgtgatt gaagtggatg gaaatagtgt tactgttaaa gtaagtagtg
     8881 caattcatcc aatgactaaa gaacatcata tagcatgggt gtatcttatg actgaacaag
     8941 gtggtcaacg caaatgtcta gcagtagatg gagaacctgt agttaaattt gctctgaatg
     9001 atgatgataa agtgatttct gcatatgctt attgtaattt acatggttta tggaaggctg
     9061 aactgtaata tttaaataaa ttgagtcaaa aaggaggcta taaatgtatt ttcatacaaa
     9121 tagcctccta taaatttata taaattcgag ttttaatttt atttaatgtc aatataatat
     9181 aaggagaaaa taatatgtca atttacaaat gtagcgtttg cggatatatt tatgatgaat
     9241 ctaagaatga taaaacatgg gatgaattaa gtgaagactg ggaatgccct gtatgtacaa
     9301 aaggtcgtag ttattttgga aagataagta ctgtttacta tgaagaagat gaaaatatag
     9361 cagaagacat agttgaagat gaacctaaat taaatactga aaaagatgga gatttaaatt
     9421 acgtaagtac atatttaaga agagatgatg aagttgagaa acatatggat ataattcacg
     9481 aaatggctgt tacaggaaaa tctataatag aaccgatgag aactaaacta ccagtaattt
     9541 cttgggatga tattttaatt atgggtgctc aattaaatcc attaccttta aacgaacatg
     9601 atgaagtaaa tacaacaaca ataataggga aaaaagcaaa gaagcctatg attatagaaa
     9661 atccagttta tatttcccac atgtcatttg gagctttatc taaagaacta aaaatagctt
     9721 tagcaaaggg tgccgctaaa agtaagacag ctatgtgtag tggagaaggt ggtatattac
     9781 cagaagaaaa agaagcttca tataagtata tttttgaata tgtaccaaat aaatatagtg
     9841 taactgaaga aaatcttaaa aattctgatg ctatagaaat aaaaattggt caaggaacaa
     9901 aacctggtat gggaggtcat cttcctggtg aaaaagtaac tgaagaaata gcaaaggtaa
     9961 gaaataagcc tgtaggtaaa gatgtaataa gtccatcttg ttttgaggaa atacaatcca
    10021 aagaagattt aaagaaactt gtagatgaac ttagagaagt ttcagaaggt cgtccaatag
    10081 gtgttaaaat ttcagctggt catattgaaa aagatatgga atttatagct tatgctaaac
    10141 ctgattttgt gactattgat ggtcgtggtg gagctactgg agcaagccca aagttgctta
    10201 aagatgcaac ttcaatccca acaatatttg cactttatcg tgctagaaaa tacatagata
    10261 cacatggatt agatatagat ttggttataa caggtgggct tcgtatatct actgattttg
    10321 ccaaggcaat tgctatgggt gctgatgcag ttgctattgc aagttctgct cttatggcag
    10381 cagcatgtca acaatatcgt atatgtggtt ctggtaagtg ccctgtagga gtagctactc
    10441 aggatgagga attgagaaaa agattacata tagaaaatag tgctaataga gtggcaaact
    10501 ttttaaatgt aagtttagaa gaacttaaga cttttgctag aatttctggt cataaagata
    10561 tacatgattt aagtgttgat gatttatata ctgttaactc tgaaatatca aattacacaa
    10621 acatacaaca tgtataagtt gaagtttgag actattagat tgtagatagt tataaaagta
    10681 aatgataaat atattttata aaaaggagtg tcttaaaatg aactttttag tttataagtc
    10741 actctttttt gtatgaagcc aaatatattt atcattttaa caatgaaaaa gaatcttata
    10801 tctttacttt gagatagatt ccttctattt atgaaaatta aagatattaa attgtaaaac
    10861 attctgtgat gtcgtactat taaactaaag atgctgtact ttaaagtaaa taaaaattta
    10921 aggagtgatt attatggaaa aattgaagat tcaagttcta gttgacaata atacatatat
    10981 tgataggtac tttgttggag aaccagcagt aagctattac attgagattg atggaaatag
    11041 gattttgttt gattaaaaaa tagctacgaa cacttgtgac tttagtc
//
LOCUS       DAMKOJ010000252         2787 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.189, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000252 DAMKOJ010000000
VERSION     DAMKOJ010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.189"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            <1..335
                     /locus_tag="PC592_003881"
     CDS             <1..335
                     /locus_tag="PC592_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF4057757.1"
                     /translation="RAEAKQDLQLLNAQKMGEHEAEIEKIKNVFLAILRDIKKDIYNG
                     EQPGEAVTAAMFQAMRDALAEQKQNPLSIDDVAAMVAGQIGQLTPMDEETADLFKQLA
                     KKMMKGIE"
     gene            360..1130
                     /locus_tag="PC592_003882"
     CDS             360..1130
                     /locus_tag="PC592_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HDF4057758.1"
                     /translation="MPLVKHDYPVLEYDTASKAVFQPGNGKKCFPAKAVFAFLGDEVE
                     NYAHTHDGIQIDEFESATRRYPIYECLYNQEKICLCPAPVGSAAAVQVLEYLIAGGVT
                     KIISVGSCGVLEDIPENRFLIPVSALRDEGTSYHYLPPSREVEISKAGINAIESALSQ
                     KNIPYWEVKTWTTDGFYRETVEMVQYRKEEGCQVVEMECSALAACAKFRKVTWAMLLF
                     SADTLADPHKYQEREWGKTSISIALELALDAVLSVVEE"
     gene            1155..1931
                     /locus_tag="PC592_003883"
     CDS             1155..1931
                     /locus_tag="PC592_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(9) family aminoglycoside
                     nucleotidyltransferase"
                     /protein_id="HDF4057759.1"
                     /translation="MNINEFPQQVNQVISIAETILQGQILGIYLYGSATMNGLRPDSD
                     IDILIITKQELSNSIRADLTKQLLKISGSVGCIEKRPLEVTIINQSDIVPLQFPPKCQ
                     YMYGEWLRGEMEAGEYPQACNDPDIMILLWQARKNSITLKGAESKELIPAIPFHEIKK
                     AIRFSLPGLISSFKGDERNVLLTLSRMWFTLVTEEITTKDVAAKWVILKLPERFPPLL
                     TTAKEAYLGNLSDEWETVEKEAMALVEYMKKQIEELLRTE"
     gene            2131..2676
                     /locus_tag="PC592_003884"
     CDS             2131..2676
                     /locus_tag="PC592_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF4057760.1"
                     /translation="MNQGRIIVITGSPGTGKTTTASIVAKESNMDKSVHMHTDDFFHY
                     LSKGAIPPHLPESNEQNLVVIEAFLEAAKRYARGGYDVIVDGIVGPWFLEPWRALVRE
                     DYEVHYIVLRASKEETMKRAVERSKLDRKTNVELVETMWEQFCNLGIYESNVIETTTY
                     SIQEAVFAVKEKISSGAALLS"
BASE COUNT          949 a          480 c          650 g          708 t
ORIGIN      
        1 accgggcgga agcaaagcag gatttacagc ttttgaacgc ccagaagatg ggggaacatg
       61 aggcggagat tgagaaaatc aaaaatgtgt tccttgctat cctgcgggat attaagaaag
      121 acatttacaa cggggaacag ccgggagaag ctgtgaccgc cgcgatgttc caagccatgc
      181 gggacgcatt ggcggaacag aagcaaaacc cgctttccat tgacgatgta gcggcgatgg
      241 ttgccggaca gatcggacag cttacgccga tggatgaaga aactgccgac ctgttcaagc
      301 agttggcaaa aaagatgatg aaaggaatag aataatagcc tgttattcga gataataata
      361 tgccattagt aaagcatgac taccctgttt tagagtacga taccgcatca aaagctgttt
      421 ttcagccggg aaatgggaaa aaatgttttc ctgcaaaagc agtgtttgct tttttaggag
      481 acgaggttga aaattatgca catacccatg atggaataca gatagatgaa tttgaaagtg
      541 caacaagacg atatcctatt tatgaatgtc tttataatca ggagaaaata tgtctatgtc
      601 cggctcctgt gggaagtgct gctgccgtcc aagttttaga atatttaatt gcagggggtg
      661 taacaaagat tatttccgtc ggctcctgcg gcgtattgga agacatcccg gaaaatagat
      721 ttttgatacc tgtttctgca ttgagagatg agggaacatc ttaccattat cttcctccct
      781 cccgagaagt agagatttca aaggctggta taaatgcgat tgaatctgct ttaagccaaa
      841 agaatatacc atattgggaa gttaaaacat ggacaacaga cggtttttat cgagaaacag
      901 tagaaatggt tcagtatcgg aaagaagagg gatgtcaagt agtagaaatg gaatgttccg
      961 cattggcggc gtgtgcaaaa tttagaaaag ttacatgggc tatgctgctt ttttcagccg
     1021 atactcttgc agaccctcat aaataccaag aaagagaatg gggaaaaaca agtatatcca
     1081 tagccttaga attagcctta gacgctgttt tatcagttgt tgaggagtaa aaataaatac
     1141 atataggagt tacaatgaat ataaatgaat ttccacaaca agtaaatcaa gttatttcaa
     1201 tagcagaaac catattacaa ggtcaaatat tggggatata tttatatggt tcagcaacaa
     1261 tgaatgggct gcgtccagat agtgatatag atatactgat aattactaaa caagaattga
     1321 gtaattcaat cagagcagat ctaacaaagc aattattgaa aatttctggc tccgtaggct
     1381 gtattgaaaa aagaccttta gaggtaacta ttatcaatca atctgatatt gttccgttgc
     1441 aatttccgcc aaaatgtcag tatatgtatg gtgaatggct aaggggagag atggaagcag
     1501 gagaatatcc gcaagcctgc aatgacccag atataatgat tttattatgg caagcaagaa
     1561 aaaatagcat aactttgaag ggggcggaaa gcaaagagct tattcccgct atcccatttc
     1621 acgaaattaa aaaagcaatt cggttttctt tacctggttt gatttccagc tttaagggtg
     1681 atgaaagaaa tgtgttatta accttatcac gaatgtggtt tactttagta acagaagaaa
     1741 tcacgacaaa agatgttgcc gcaaaatggg taattttaaa attgccggag agattccccc
     1801 ccctgctaac aacggcaaag gaagcttatt tgggaaattt gtctgatgaa tgggagacag
     1861 tagaaaagga agcgatggca cttgtagaat atatgaaaaa acaaattgag gaattactta
     1921 gaacagagta gcaaagttag cggggccaat caacggtcaa gatgaacggc gcataaatgc
     1981 gccgccgttg acagtcccgc ccgtctttgc tgatgggcaa tcaaggcggg aaagccctaa
     2041 aatggcttcc cgcccatttc aatcttgaga gaagaaacgc tccaaaacca gaaagagagc
     2101 ggtaaatctg aattgcgagg gagaatgtag atgaatcaag gaagaattat tgtgattaca
     2161 ggttcgccgg gaacaggaaa gacaacaact gcgtcgattg tcgcaaaaga atcgaacatg
     2221 gataaatctg tgcatatgca cacagacgac ttttttcatt atttaagcaa aggagcaata
     2281 ccgccgcatt taccagagtc caacgaacaa aatttagttg tcattgaagc ctttttagaa
     2341 gctgcaaagc gctatgcccg cggcggatat gatgtaattg tagatggaat tgtcgggccg
     2401 tggtttttag aaccatggag agcccttgtt cgagaagatt atgaagtaca ctatattgtt
     2461 ttaagagcca gtaaagaaga aactatgaaa cgagctgtgg aacgctcaaa attagacaga
     2521 aaaacaaatg ttgaattagt agaaacaatg tgggagcaat tttgtaattt ggggatatat
     2581 gaatcgaatg ttatagaaac gacaacctat tctatccaag aggctgtttt tgcagtaaaa
     2641 gaaaaaattt caagtggagc cgcattgcta tcttaaacga tttctaaaaa tcgaaatttc
     2701 atttatcaga gaaatagcaa aggcagccaa gccagtcaac ggtcaaaatg aacggcgcat
     2761 ttcatgcgcc gccgttgaca gtcccgc
//
LOCUS       DAMKOJ010000253         1096 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104057 isolate JH525
            SAMN32366334-rid16591873.guided.215, whole genome shotgun sequence.
ACCESSION   DAMKOJ010000253 DAMKOJ010000000
VERSION     DAMKOJ010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366334
            Sequence Read Archive: SRR22862783
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560639.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,885
            CDSs (total)                      :: 3,830
            Genes (coding)                    :: 3,728
            CDSs (with protein)               :: 3,728
            Genes (RNA)                       :: 55
            rRNAs                             :: 7, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 34 of 102
            Pseudo Genes (incomplete)         :: 79 of 102
            Pseudo Genes (internal stop)      :: 26 of 102
            Pseudo Genes (multiple problems)  :: 30 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1096
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366334-rid16591873.guided.215"
                     /strain="L,15.7104057"
                     /isolate="JH525"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2014"
     gene            111..977
                     /locus_tag="PC592_003885"
     CDS             111..977
                     /locus_tag="PC592_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase AadE"
                     /protein_id="HDF4057761.1"
                     /translation="MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFD
                     ITFFVTDMDSFTSDDKWLDIFGERLILQKPEDMELFPAVEKGFSYLMLFTDDVKIDLT
                     LLPLELIDEYFTWDKLVKLLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHMNDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYVP
                     EELWERLMSTYNMDSYPHMWESFEQCMALFREVSSEVACQLDYQYPLYDEKISNYVIR
                     QKKKYGIEDDNK"
BASE COUNT          364 a          174 c          227 g          331 t
ORIGIN      
        1 catttcatgc gccgccgttg acagtcccgc ccgtctttgc taaagggtaa tcaaggcggg
       61 aaagccctaa aatggtttca cacctatttc aataattgga ggagataaaa atgagatcag
      121 aaaaggaagt ttatgatatt gttttgaatt ttgcaaaaac agacaaacgc attcgcatgg
      181 ttactttgga aggatctaga acaaatacaa atattccgcc tgatgatttt caggattttg
      241 atattacttt ttttgttacg gatatggaca gcttcacaag tgatgataaa tggctagata
      301 tatttggtga aaggttgatt ctgcaaaagc cggaagatat ggaattattt ccagctgtag
      361 aaaagggatt ttcatattta atgctgttta ctgatgatgt taagatagat ttaactttgc
      421 tgccgctgga actgatagac gagtatttta catgggataa actggtaaag ttactgttgg
      481 ataaagacaa ccgtatcgta aagccgccaa taccaacgga tatagactac cacttgcaga
      541 agcctactca aagaatgttt gacgattgct gtaatgaatt ttggaatact acaacatatg
      601 tagtaaaggg cttatgccgc aaagaaattc tttttgctat tgaccatatg aatgatatag
      661 tacgaaaaga attgcttcgc atgatttcct ggctgattgg tatcaaacag ggatttcatt
      721 tcagtttggg aaaaaactat aaatttatga agcaatatgt cccagaggaa ttgtgggaac
      781 gacttatgtc cacttataat atggattcct atccccatat gtgggaatcc tttgaacaat
      841 gtatggcatt gttccgggag gtttcgtcag aagtggcatg ccagttggat taccagtatc
      901 cactatatga tgaaaaaatc agtaattatg tgattcggca aaagaaaaaa tatggcattg
      961 aagatgataa caaataaaat tttttcaatc gaaaaaattt attttgatta ttcaattttg
     1021 aaaaactgaa tacctcaaaa tcagaaagag cgcggacaag cactttgagg gattggccgc
     1081 cttgtccacc cattca
//
